title: The influence of arterial insufficiency and venous congestion on composite graft survival.
abstract: A rabbit auricular amputation model was used to study the relative effects of arterial insufficiency (AI) and venous congestion (VC) on composite graft survival. The percentage of graft survival was significantly greater for the AI group (45.8%) than for the VC group (15.9%) 2 weeks postoperatively. The percentage of graft survival at 3 weeks for the VC, AI, and noligation groups were not statistically different. All three groups were statistically different from the control group, which had both the central artery and vein ligated. The VC group also exhibited significantly more graft edema, as measured by maximal graft thickness, than the other three groups. The impact of AI and VC on composite graft survival is investigated and discussed. These results suggest that venous congestion is more detrimental to early graft survival than arterial insufficiency.
authors.affiliation: Division of Otolaryngology/Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill 27599-7070, USA.
authors.forename: D E
authors.initials: DE
authors.lastname: Henrich
authors.forename: R S
authors.initials: RS
authors.lastname: Lewis
authors.forename: T C
authors.initials: TC
authors.lastname: Logan
authors.forename: W W
authors.initials: WW
authors.lastname: Shockley
mesh_terms: D000818:Animals; D004425:Ear Cartilage / Q000637:transplantation; D004431:Ear, External / Q000098:blood supply* / Q000601:surgery*; D004487:Edema / Q000503:physiopathology; D006085:Graft Survival / Q000502:physiology*; D007511:Ischemia / Q000503:physiopathology*; D011817:Rabbits; D016038:Skin Transplantation / Q000502:physiology