title: Pulmonary consequences of carbon dioxide insufflation for laparoscopic cholecystectomies.
abstract: Twenty patients having laparoscopic cholecystectomies were studied for changes in thoracic and lung compliance at 5, 10 and 15 mmHg of intra-abdominal pressure. Fifteen mmHg of intra-abdominal pressure decreased the thoracic and the lung static compliance by 49 and 39% respectively. This was unaffected by the degree of head elevation. During the procedure the end-tidal carbon dioxide increased by a mean of 1.6 kPa at 1 h and 2.0 kPa at 2 h. This did not appear to be related to either the mean intra-abdominal pressure or the total volume of carbon dioxide insufflated. The physiological changes and implications for anaesthetic practice are considered.
authors.affiliation: Department of Anaesthesia and Intensive Care, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Sha Tin, New Territories.
authors.forename: A P
authors.initials: AP
authors.lastname: Kendall
authors.forename: S
authors.initials: S
authors.lastname: Bhatt
authors.forename: T E
authors.initials: TE
authors.lastname: Oh
mesh_terms: D000005:Abdomen / Q000502:physiology; D000328:Adult; D002245:Carbon Dioxide / Q000008:administration & dosage* / Q000378:metabolism; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D006801:Humans; D007327:Insufflation; D008168:Lung / Q000502:physiology; D008170:Lung Compliance / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010313:Partial Pressure; D011312:Pressure; D013909:Thorax / Q000502:physiology
chemical_list: D002245:Carbon Dioxide