In vitro susceptibility of Campylobacter and Salmonella isolates from broilers to quinolones, ampicillin, tetracycline, and erythromycin.
Recently, an increased resistance of Campylobacter to fluoroquinolones, a newer class of antimicrobial agents in both human and veterinary medicine, has been reported. Campylobacter isolates (617) from 150 broiler flocks were tested for their susceptibility to cephalothin (control), ampicillin, tetracycline, erythromycin, and the quinolones nalidixic acid, flumequine, enrofloxacin, and ciprofloxacin by a disc diffusion method. Almost complete cross-resistance was found between the quinolones tested. Campylobacter isolates (181, 29%), originating from 55 flocks (37%), were quinolone resistant. Salmonella isolates (94) from 40 flocks were also tested for their antimicrobial susceptibility. Eight isolates (8.5%), from three broiler flocks (7.5%), showed resistance to nalidixic acid and flumequine (and tetracycline), but not to ciprofloxacin or enrofloxacin.
Jacobs-Reitsma
W F
WF
Institute for Animal Science and Health (ID-DLO), Branch Beekbergen, The Netherlands.
Koenraad
P M
PM
Bolder
N M
NM
Mulder
R W
RW
D042462:4-Quinolones; D000667:Ampicillin / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002167:Campylobacter / Q000187:drug effects* / Q000302:isolation & purification; D002169:Campylobacter Infections / Q000382:microbiology / Q000662:veterinary; D002645:Chickens / Q000382:microbiology*; D004917:Erythromycin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D009426:Netherlands; D011201:Poultry Diseases / Q000382:microbiology; D012475:Salmonella / Q000187:drug effects* / Q000302:isolation & purification; D012481:Salmonella Infections, Animal / Q000382:microbiology; D013752:Tetracycline / Q000494:pharmacology
D042462:4-Quinolones; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D004917:Erythromycin; D000667:Ampicillin; D013752:Tetracycline