Envelope V3 region sequences of Cuban HIV-1 isolates.
The origin of HIV-1 species, responsible for the AIDS epidemic in Cuba, is a subject that has been intensely debated. This study represents an initial attempt to shed light on this issue, through sequence analysis of the V3 regions of viruses isolated from 15 Cuban subjects. We now report that these viruses fall within three distinct, well-recognized groupings. These findings suggest that viruses of different sources are responsible for the HIV/AIDS epidemic in Cuba.
Rolo
F M
FM
National AIDS Research Laboratory, Havana, Cuba.
Miranda
L
L
Wainberg
M A
MA
Gu
Z
Z
Lobaina
L
L
Noa
E
E
Mato
J
J
Machado
F
F
Martin
Z
Z
D000163:Acquired Immunodeficiency Syndrome / Q000635:transmission / Q000821:virology*; D000595:Amino Acid Sequence; D001483:Base Sequence; D002460:Cell Line; D002478:Cells, Cultured; D003462:Cuba; D018562:Disease Transmission, Infectious; D005260:Female; D015752:Genes, env; D015699:HIV Envelope Protein gp120 / Q000235:genetics*; D015658:HIV Infections / Q000635:transmission / Q000821:virology*; D015497:HIV-1 / Q000235:genetics* / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000235:genetics*; D016133:Polymerase Chain Reaction; D013601:T-Lymphocytes / Q000821:virology
D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments