title: Measurements of the growth and distribution of mammalian cells in a hollow-fiber bioreactor using nuclear magnetic resonance imaging.
abstract: We have used diffusion-weighted 1H NMR micro-imaging and localized spectroscopy techniques to monitor the growth and distribution of mammalian cells in a hollow-fiber bioreactor. Non-invasive NMR measurements of this type should also allow investigation of metabolic heterogeneity and assist in future designs of hollow-fiber systems.
authors.affiliation: Department of Biological Sciences, University of Manchester, UK.
authors.forename: R
authors.initials: R
authors.lastname: Callies
authors.forename: M E
authors.initials: ME
authors.lastname: Jackson
authors.forename: K M
authors.initials: KM
authors.lastname: Brindle
mesh_terms: D002455:Cell Division; D002477:Cells / Q000166:cytology*; D003584:Cytological Techniques; D004058:Diffusion; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D013057:Spectrum Analysis; D014867:Water
chemical_list: D014867:Water