Flow cytometric DNA analysis of classic and steroid-induced Kaposi's sarcoma.
Flow cytometric DNA analysis of various tumours has indicated a correlation between the degree of malignancy and ploidy; results which could have clinical significance. We analysed the ploidy of Kaposi's sarcoma (KS) tumours, and classified the results according to clinical history and histological findings. We found that patients on steroid treatment had an aneuploid pattern, and most of the patients with classic-type KS had a diploid pattern on flow cytometry.
Reizis
Z
Z
Department of Dermatology, Beilinson Medical Center, Petah Tiqva, Israel.
Trattner
A
A
Katzenelson
V
V
David
M
M
Rotem
A
A
Nativ
O
O
Mor
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000032:analysis*; D004171:Diploidy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000009:adverse effects; D012514:Sarcoma, Kaposi / Q000139:chemically induced / Q000235:genetics*
D004273:DNA, Neoplasm; D011241:Prednisone