title: A simultaneous evaluation of three multiparametric coagulation instruments: BFA, HEMOLAB and STA.
abstract: In the present paper, three multiparametric coagulation instruments were evaluated with regard to chronometric tests for aPTT (CK-Prest and automated APTT), PT (Recombiplastin and Thromborel), fibrinogen and factors of the prothrombin complex. Analysis of within-run precision and linearity and comparative studies showed the analytical performances of the instruments to differ according to the reagents used and emphasized the difficulty of finding the best compromise between instrument and reagent. On the basis of this study, the mechanical instrument appeared to be more versatile than the optical machines. This conclusion could however be modified after further evaluation of the recent new generation coagulation instruments.
authors.affiliation: Laboratoire d'Hématologie, CHU de Grenoble, France.
authors.forename: G
authors.initials: G
authors.lastname: Pernod
authors.forename: B
authors.initials: B
authors.lastname: Bouabana
authors.forename: B
authors.initials: B
authors.lastname: Desrousseau
authors.forename: P
authors.initials: P
authors.lastname: Mossuz
authors.forename: J M
authors.initials: JM
authors.lastname: Drevait
authors.forename: B
authors.initials: B
authors.lastname: Maljournal
authors.forename: D
authors.initials: D
authors.lastname: Rouhan
authors.forename: L
authors.initials: L
authors.lastname: Kolodié
authors.forename: B
authors.initials: B
authors.lastname: Polack
mesh_terms: D001780:Blood Coagulation Tests / Q000295:instrumentation*; D005069:Evaluation Studies as Topic; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D016014:Linear Models; D010314:Partial Thromboplastin Time; D011517:Prothrombin Time; D015203:Reproducibility of Results
chemical_list: D005340:Fibrinogen