title: [Clinico-pathological aspect of HIV-sero positive inpatients].
abstract: To describe the clinico-pathological aspect of HIV/AIDS inpatients, we reviewed HIV/AIDS inpatients in our hospital since 1988. We evaluated risk factors, CD4 counts, CD4/8 ratio, cause of death and the survival time after diagnosis of AIDS. A total of 13 HIV sero-positive subjects were admitted to our hospital, including 11 cases (85%) with AIDS. One patient was a foreigner. All cases were male; age range 18-70 years. Hemophiliacs and sexually transmitted patients account for 62% and 38% of cases, respectively. There were no cases of intravenous drug users. In all cases with AIDS, CD4+ cells and CD4/8 ratio significantly decreased with median value of 73/microns and 0.18, respectively. Six cases (54%) were decreased and autopsy were done in four cases. Findings of autopsy revealed HIV encephalopathy and systemic various infection, including Pneumocystis carinii, cytomegalovirus, papilloma virus and pox virus. Cytomegalovirus infection was found in all cases; one had innumerable inclusion bodies in lung, adrenal gland and intestines. The median survival time after diagnosis of AIDS were 26 months.
authors.affiliation: First Department of Internal Medicine, Yokohama City University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Fujita
authors.forename: T
authors.initials: T
authors.lastname: Soga
authors.forename: J
authors.initials: J
authors.lastname: Suzuki
authors.forename: Y
authors.initials: Y
authors.lastname: Ishigatsubo
authors.forename: H
authors.initials: H
authors.lastname: Mohri
authors.forename: T
authors.initials: T
authors.lastname: Okubo
authors.forename: Y
authors.initials: Y
authors.lastname: Nagashima
authors.forename: K
authors.initials: K
authors.lastname: Misugi
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000209:etiology / Q000473:pathology; D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D015704:CD4 Antigens / Q000032:analysis; D016516:CD4-CD8 Ratio; D006679:HIV Seropositivity / Q000276:immunology / Q000473:pathology*; D006467:Hemophilia A / Q000150:complications; D006760:Hospitalization; D006801:Humans; D008297:Male
chemical_list: D015704:CD4 Antigens