Identification of mast cells in buffy coat preparations from dogs with inflammatory skin diseases.
In 100 dogs with 4 inflammatory dermatologic diseases, buffy coat preparations from EDTA-treated blood samples were examined cytologically. Fifty-four dogs had atopy, 26 had flea-bite hypersensitivity, 17 had sarcoptic mange, and 3 had food allergy. Twenty-eight dogs had 2 or more concurrent skin diseases; most of these had secondary pyoderma. Dogs did not have mast cell tumors. Thirteen samples contained 1 or more mast cells/4 slides reviewed. This study revealed that dogs with inflammatory skin diseases can have a few to many mast cells evident on cytologic examination of buffy coat preparations.
Cayatte
S M
SM
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
McManus
P M
PM
Miller
W H
WH
Scott
D W
DW
D000818:Animals; D003872:Dermatitis / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D003876:Dermatitis, Atopic / Q000097:blood / Q000473:pathology / Q000662:veterinary; D004283:Dog Diseases / Q000097:blood* / Q000473:pathology; D004285:Dogs; D005512:Food Hypersensitivity / Q000097:blood / Q000473:pathology / Q000662:veterinary; D007299:Insect Bites and Stings / Q000276:immunology / Q000662:veterinary; D008407:Mast Cells / Q000473:pathology*; D012532:Scabies / Q000097:blood / Q000473:pathology / Q000662:veterinary