title: Invasive Haemophilus influenzae type b infections in children hospitalized in Hong Kong, 1986-1990. Hong Kong Hib Study Group.
abstract: A 5-year territory-wide retrospective survey of invasive Haemophilus influenzae type b diseases was conducted in Hong Kong. Between 1986 and 1990, 57 cases (28 male) were recorded in children less than 12 years old (37 cases of meningitis, 9 of septicaemia and 11 of bacteraemic pneumonia). The annual incidence for children less than 5 years old was 2.7 per 10(5) (95% confidence interval (CI) 2.0-3.5). Of the 57 cases, 39 were Chinese and 18 non-Chinese (7 Vietnamese refugees, 6 Caucasians, 5 others). The annual incidence in Vietnamese refugees less than 5 years old was 42.7 per 10(5) (95% CI 17.2-87.9), giving a relative risk of 18.5 (95% CI 8.3-41.0). Chinese patients (68%) were under-represented as Chinese accounted for at least 94% of the population. Moreover, 14 of the 39 Chinese patients had pre-existing medical problems, compared with only 1 of the 18 non-Chinese patients patients had pre-existing medical problems, compared with only 1 of the 18 non-Chinese patients (p = 0.022).
authors.affiliation: Department of Paediatrics, Queen Mary Hospital, University of Hong Kong.
authors.forename: Y L
authors.initials: YL
authors.lastname: Lau
authors.forename: L C
authors.initials: LC
authors.lastname: Low
authors.forename: R
authors.initials: R
authors.lastname: Yung
authors.forename: K W
authors.initials: KW
authors.lastname: Ng
authors.forename: C W
authors.initials: CW
authors.lastname: Leung
authors.forename: W H
authors.initials: WH
authors.lastname: Lee
authors.forename: A
authors.initials: A
authors.lastname: Ho
authors.forename: S J
authors.initials: SJ
authors.lastname: Oppenheimer
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China / Q000208:ethnology; D005260:Female; D006192:Haemophilus Infections / Q000453:epidemiology*; D006193:Haemophilus influenzae; D006723:Hong Kong / Q000453:epidemiology; D006760:Hospitalization / Q000639:trends; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011159:Population Surveillance; D012189:Retrospective Studies; D014744:Vietnam / Q000208:ethnology; D044465:White People