Measurements of the growth and distribution of mammalian cells in a hollow-fiber bioreactor using nuclear magnetic resonance imaging.
We have used diffusion-weighted 1H NMR micro-imaging and localized spectroscopy techniques to monitor the growth and distribution of mammalian cells in a hollow-fiber bioreactor. Non-invasive NMR measurements of this type should also allow investigation of metabolic heterogeneity and assist in future designs of hollow-fiber systems.
Callies
R
R
Department of Biological Sciences, University of Manchester, UK.
Jackson
M E
ME
Brindle
K M
KM
D002455:Cell Division; D002477:Cells / Q000166:cytology*; D003584:Cytological Techniques; D004058:Diffusion; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D013057:Spectrum Analysis; D014867:Water
D014867:Water