Two components of GABA-induced currents in catfish retinal horizontal cells.
In cone-driven horizontal cells dissociated from the catfish retina, we recorded GABA-induced currents by using a whole-cell voltage-clamp technique. The current consisted of two components. The major component was blocked by picrotoxin, but not by bicuculline, and was identified as a current flowing through the GABAC receptor channel. The second minor component was identified as a current carried by an electrogenic GABA transporter.
Takahashi
K
K
Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
Miyoshi
S
S
Kaneko
A
A
D000818:Animals; D002352:Carrier Proteins / Q000502:physiology*; D002397:Catfishes; D018408:Patch-Clamp Techniques; D018079:Receptors, GABA; D012160:Retina / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D002352:Carrier Proteins; D018079:Receptors, GABA; D005680:gamma-Aminobutyric Acid