Structure-activity relationships of synthetic tigogenyl glycosides.
Haemolytic activities of the five tigogenyl diglycosides and a maltotrioside were much stronger than those of nine monoglycosides. Among these glycosides, the glucoside, galactoside, maltoside, lactoside, gentiobioside, melibioside and maltotrioside had strong antifungal activity. By contrast, none of these glycosides showed any antibacterial activity.
Takechi
M
M
Faculty of Pharmaceutical Sciences, Kinki University, Higashiosaka, Japan.
Tanaka
Y
Y
D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D002240:Carbohydrate Sequence; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology; D006460:Hemolysin Proteins / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D013150:Spirostans / Q000737:chemistry*; D013329:Structure-Activity Relationship
D000890:Anti-Infective Agents; D000935:Antifungal Agents; D006027:Glycosides; D006460:Hemolysin Proteins; D013150:Spirostans; C046297:sarsasapogenin