title: [Primary malignant tumours in submandibular region].
abstract: From 1959 and 1989, 65 patients with primary malignant tumour of submandibular region, including 18 cases of adenoid cystic carcinoma, 16 cases of malignant mixed tumour, 14 cases of adenoid carcinoma, 10 cases of undiferentiated carcinoma and 7 cases of squamous cell carcinoma, were treated at this hospital by surgery or combined therapy. The 3- and 5-year survivals were 60% and 42.9%, respectively. Those of malignant mixed tumours were somewhat better, being 75% and 61.5%. Submandibular gland excision or regional/elective dissection was used if the tumours were local and no capsule invasion. Particular attention was given to the identification of perineural invasion, softtisure extension, bone invasion and lymph node metastasis. Wide excision and neck dissection were necessary for above mentioned pathological changes. Combined therapy was important for those patients with positive margin, recurrence, low- or un-differentiation and advanced stage. The main factors affecting survival were local-regional failure.
authors.affiliation: Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
authors.forename: C
authors.initials: C
authors.lastname: Jia
authors.forename: G
authors.initials: G
authors.lastname: Tu
mesh_terms: D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D018198:Mixed Tumor, Malignant / Q000401:mortality / Q000473:pathology / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D013365:Submandibular Gland Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate