title: [Interspecific differences in kemantan pharmacokinetics].
abstract: The pharmacokinetics of the new immunostimulant kemantane, adamantane derivative, used in two species of animals (rats and rabbits) and man was studied. There were significant differences in the pharmacokinetics of kemantane and its active metabolite--adamantane-1,4-diol between the species.
authors.forename: S S
authors.initials: SS
authors.lastname: Boĭko
authors.forename: V P
authors.initials: VP
authors.lastname: Zherdev
authors.forename: N A
authors.initials: NA
authors.lastname: Kisliak
authors.forename: B M
authors.initials: BM
authors.lastname: Piatin
authors.forename: N V
authors.initials: NV
authors.lastname: Klimova
authors.forename: P V
authors.initials: PV
authors.lastname: Glan
authors.forename: A A
authors.initials: AA
authors.lastname: Dvorianinov
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives* / Q000097:blood / Q000493:pharmacokinetics; D000276:Adjuvants, Immunologic / Q000097:blood / Q000493:pharmacokinetics*; D000818:Animals; D001991:Bronchitis / Q000097:blood / Q000188:drug therapy; D002849:Chromatography, Gas; D002908:Chronic Disease; D006801:Humans; D008297:Male; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; C068220:kemantane; D000218:Adamantane
vernacular_title: Mezhvidovye razlichiia farmakokinetiki kemantana.