Analysis of homozygous TGF beta 1 null mouse embryos demonstrates defects in yolk sac vasculogenesis and hematopoiesis.
Martin
J S
JS
Department of Medical Genetics, University of Glasgow, Duncan Guthrie Institute of Medical Genetics, Yorkhill, United Kingdom.
Dickson
M C
MC
Cousins
F M
FM
Kulkarni
A B
AB
Karlsson
S
S
Akhurst
R J
RJ
D000818:Animals; D004622:Embryo, Mammalian / Q000502:physiology*; D005314:Embryonic and Fetal Development; D005260:Female; D005786:Gene Expression Regulation; D005804:Genes, Lethal; D006410:Hematopoiesis; D006720:Homozygote; D008648:Mesoderm / Q000166:cytology / Q000502:physiology; D051379:Mice; D018345:Mice, Knockout; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D010641:Phenotype; D011247:Pregnancy; D016212:Transforming Growth Factor beta / Q000096:biosynthesis* / Q000235:genetics; D015017:Yolk Sac / Q000098:blood supply / Q000502:physiology*
D016212:Transforming Growth Factor beta