title: [Acute necrotizing enterocolitis during a prolonged treatment with neuroleptics].
abstract: A 32-year old man treated for several years with phenothiazine for chronic psychosis developed acute necrotizing colitis. The causal relationship with neuroleptics was reinforced by the absence of any other treatment and by histological findings including extensive mucosal necrosis without stenotic lesion and without mesenteric vessels alteration. The patient required emergency total colectomy and was discharged after 7 weeks of hospitalisation in the intensive care unit.
authors.affiliation: Service de Réanimation médicale et Maladies infectieuses, Centre Hospitalier de Tourcoing.
authors.forename: A
authors.initials: A
authors.lastname: Ausseur
authors.forename: C
authors.initials: C
authors.lastname: Leroy
authors.forename: B
authors.initials: B
authors.lastname: Bazin
authors.forename: B
authors.initials: B
authors.lastname: Sarraz-Bournet
authors.forename: J
authors.initials: J
authors.lastname: Oureib
authors.forename: H
authors.initials: H
authors.lastname: Georges
mesh_terms: D000208:Acute Disease; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D010640:Phenothiazines; D011618:Psychotic Disorders / Q000188:drug therapy; D013997:Time Factors
chemical_list: D014150:Antipsychotic Agents; D010640:Phenothiazines
vernacular_title: Entérocolite aiguë nécrosante au cours d'un traitement prolongé par neuroleptiques.