title: Lack of relationship between hair lead levels and some usual markers (blood lead levels, ZPP, urinary ALA-D) in occupationally exposed workers.
abstract: Blood and hair samples collected from 54 male workers occupationally exposed to lead were assayed for this metal by graphite furnace atomic absorption spectrophotometry. Blood ZPP and urinary ALA-D were also determined for most subjects tested. Blood and hair lead concentrations (PbB and PbH) ranged from 100 to 770 ng/ml (10 to 77 micrograms/100 ml) (mean +/- SD: 384.6 +/- 143.4 ng/ml (38.46 +/- 14.34 micrograms/100 ml)), and from 3 to 243 ng/mg (mean +/- SD: 102.4 +/- 72.6 ng/mg), respectively. No correlation was observed between the PbH and PbB values, nor between PbH and ZPP or ALA-D values. Neither hair coloration nor subjects' age were related to PbH levels. Results are discussed in the light of the existing literature.
authors.affiliation: Institut de médecine légale, Strasbourg, France.
authors.forename: A
authors.initials: A
authors.lastname: Tracqui
authors.forename: M A
authors.initials: MA
authors.lastname: Bosque
authors.forename: V
authors.initials: V
authors.lastname: Costa
authors.forename: P
authors.initials: P
authors.lastname: Kintz
authors.forename: F
authors.initials: F
authors.lastname: Siegel
authors.forename: P
authors.initials: P
authors.lastname: Mangin
mesh_terms: D000328:Adult; D000367:Age Factors; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007854:Lead / Q000032:analysis* / Q000097:blood; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D000623:Porphobilinogen Synthase / Q000652:urine*; D011524:Protoporphyrins / Q000097:blood*; D013054:Spectrophotometry, Atomic; D014838:Volunteers
chemical_list: D011524:Protoporphyrins; C017803:zinc protoporphyrin; D007854:Lead; D000623:Porphobilinogen Synthase