title: Central precocious puberty: evaluation by neuroimaging.
abstract: To evaluate the incidence of abnormal intracranial findings in children with central precocious puberty, 62 children (51 girls, 11 boys) were examined by computerized tomography and/or magnetic resonance imaging (MRI) of the brain. Forty-four had normal examinations; 18 (11 girls, 7 boys) showed intracranial pathologies, including hamartoma of the tuber cinereum (8 cases), parenchymal loss (3 cases), hypothalamic-chiasmatic lesions (2 cases), lesions of the corpus callosum (2 cases), suprasellar cyst (1 case), and pineal cyst and mesiotemporal sclerosis (1 case each). Based on the correlation between the clinical and the imaging results of this series, the authors recommend MRI as the imaging method of choice in the investigation of precocious puberty.
authors.affiliation: Department of Pediatric Imaging, Children's Medical Center of Israel, Beilinson Medical Campus, Petah Tiqva.
authors.forename: L
authors.initials: L
authors.lastname: Kornreich
authors.forename: G
authors.initials: G
authors.lastname: Horev
authors.forename: S
authors.initials: S
authors.lastname: Blaser
authors.forename: D
authors.initials: D
authors.lastname: Daneman
authors.forename: R
authors.initials: R
authors.lastname: Kauli
authors.forename: M
authors.initials: M
authors.lastname: Grunebaum
mesh_terms: D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006222:Hamartoma / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D011629:Puberty, Precocious / Q000150:complications* / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014371:Tuber Cinereum / Q000000981:diagnostic imaging / Q000473:pathology