title: Evaluation of volume selection methods in in vivo MRS. Design of a new test phantom.
abstract: In vivo MR spectroscopy (MRS) requires some kind of volume selection method to be able to measure the signal from a selected part of the body. To be able to interpret the spectra correctly, the quality of the volume selection must be investigated for each new MRS application using phantom measurements. A new phantom, especially suitable for precision measurements of the volume selection performance, is presented. It contains a small, remotely controlled signal source placed inside a larger vessel. This principle can be applied to various body regions, coil types and nuclei. The measurement conditions are close to the clinical situation. The phantom does not have to be repositioned during a signal profile measurement and the signal contribution from each point along the profile is determined regarding sign and amplitude.
authors.affiliation: Department of Radiation Physics, Sahlgren's Hospital, University of Gothenburg, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Starck
authors.forename: R
authors.initials: R
authors.lastname: Lundin
authors.forename: E
authors.initials: E
authors.lastname: Forssell-Aronsson
authors.forename: M
authors.initials: M
authors.lastname: Arvidsson
authors.forename: M
authors.initials: M
authors.lastname: Alpsten
authors.forename: S
authors.initials: S
authors.lastname: Ekholm
mesh_terms: D001921:Brain / Q000378:metabolism; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D005583:Fourier Analysis; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation* / Q000379:methods*; D008961:Models, Structural; D010756:Phosphoric Acids / Q000737:chemistry; D010758:Phosphorus / Q000378:metabolism; D010759:Phosphorus Isotopes; D011786:Quality Control; D012965:Sodium Chloride; D014018:Tissue Distribution; D014867:Water
chemical_list: D010756:Phosphoric Acids; D010759:Phosphorus Isotopes; D014867:Water; D010758:Phosphorus; D012965:Sodium Chloride; C030242:phosphoric acid