[Effects of interferon on infant with CMV hepatitis].
Fifty-seven patients with CMV hepatitis, who were within 3 months of age, were treated with interferon from August 1992 to April 1993. They were randomized to be assigned to two groups. There were 30 patients in the therapeutic group, who were given daily interferon 1,000,000 u intramuscularly for 10 days and 27 patients in the control group, who were put on daily vitamin C and inosine therapy intravenously for 10 days. The results showed that there was a significant difference in the aspects of jaundice disappearance, liver and serum SGPT recovery time between the two groups. In the therapeutic group, the average alleviating time of jaundice, hepatomegaly and serum SGPT level after treatment with interferon were 15.26, 29.89 and 14.26 days ahead of those in the control group, respectively. The cure rate at one month and two months after treatment was 43.0% and 90.0% in the therapeutic group, respectively; 18.5% and 48.0% in the control group, respectively.
Chen
Y
Y
Yao
Y
Y
Tang
S
S
Chen
J
J
Yuan
L
L
D003586:Cytomegalovirus Infections / Q000628:therapy*; D005260:Female; D006525:Hepatitis, Viral, Human / Q000628:therapy* / Q000821:virology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007371:Interferon-gamma / Q000627:therapeutic use*; D008297:Male
D007371:Interferon-gamma