title: Fibrotic-haemorrhagic reaction to synthetic dural substitute.
abstract: A case is presented in which a patient developed a complication related to the use of Silastic dural substitute. Ten years after the initial surgery, a fibrotic-haemorrhagic reaction around the graft material was found, mimicking a recurrent meningioma clinically and radiologically. A review of the literature and suggested mechanisms of these complications are reported.
authors.affiliation: Department of Neurosurgery, University of Genoa, Medical School, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Siccardi
authors.forename: A
authors.initials: A
authors.lastname: Ventimiglia
mesh_terms: D002543:Cerebral Hemorrhage / Q000473:pathology / Q000601:surgery*; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000473:pathology / Q000601:surgery*; D005355:Fibrosis; D005549:Foreign-Body Reaction / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery*; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000473:pathology / Q000601:surgery*; D019736:Prostheses and Implants; D012826:Silicone Elastomers
chemical_list: D012826:Silicone Elastomers