title: Two macroprolactinomas presenting with neurological signs.
abstract: Macroprolactinomas commonly cause pressure effects on immediate parasellar structures, in particular on the optic chiasm to cause visual field defects. Pressure on more distant brain structures is rarely reported. We describe two massive prolactinomas presenting with neurological signs, including signs of hemiparesis which, to our knowledge, has not been reported previously.
authors.affiliation: Department of Endocrinology, Leicester Royal Infirmary, UK.
authors.forename: E G
authors.initials: EG
authors.lastname: Khan
authors.forename: T A
authors.initials: TA
authors.lastname: Howlett
mesh_terms: D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use; D005260:Female; D006429:Hemiplegia / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications* / Q000188:drug therapy; D015175:Prolactinoma / Q000150:complications* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000209:etiology; D014794:Visual Fields
chemical_list: D001971:Bromocriptine