Histocompatibility leukocyte antigens in Rokitansky-Küster-Hauser syndrome.
Histocompatibility leukocyte antigens of 32 patients with Rokitansky-Küster-Hauser syndrome were compared with a control healthy population of 100. For analysis chi 2 with Yates' correction and Bonferroni criterion for multiple comparisons were used. Seven antigens were significant in the chi 2 test, but only three were confirmed in the Bonferroni criterion (Aw19, DRw52, and DQw1) (p < 0.001). The study showed certain associations between Rokitansky-Küster-Hauser syndrome and the major histocompatibility complex.
Dabirashrafi
H
H
Endoscopy and Fertility Research Center, Mirza Kouchek Khan Hospital, Tehran, Iran.
Mohammad
K
K
Nikbin
B
B
Tabrizi
N M
NM
Azari
A
A
D000015:Abnormalities, Multiple / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D016009:Chi-Square Distribution; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens / Q000032:analysis; D006683:HLA-DQ Antigens / Q000032:analysis; D006684:HLA-DR Antigens / Q000032:analysis; D059810:HLA-DR Serological Subtypes; D006801:Humans; D009095:Mullerian Ducts / Q000002:abnormalities; D013577:Syndrome; D014599:Uterus / Q000002:abnormalities*; D014621:Vagina / Q000002:abnormalities*
D006680:HLA Antigens; D015234:HLA-A Antigens; C043205:HLA-A19 antigen; D006683:HLA-DQ Antigens; C051568:HLA-DQ1 antigen; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C051104:HLA-DR52 antigen