title: Otolaryngology-head and neck surgery.
abstract: Molecular analysis of surgical margins may provide greater accuracy in predicting local recurrence. The high frequency of associated p53 mutations implicates tobacco in the molecular progression that eventuates in head and neck squamous cell carcinoma.
authors.affiliation: Johns Hopkins University School of Medicine, Baltimore, Md, USA.
authors.forename: J K
authors.initials: JK
authors.lastname: Niparko
authors.forename: M E
authors.initials: ME
authors.lastname: Johns
mesh_terms: D006801:Humans; D010036:Otolaryngology / Q000639:trends*; D014481:United States