Cytokines, inflammation, and autoimmune diseases.
The understanding of cytokines is in its infancy, but it appears that overproduction or deficiency of these intracellular mediators may contribute to inflammatory and autoimmune diseases such as insulin-dependent diabetes mellitus and rheumatoid arthritis. As the complexities of cytokine actions and interactions are unraveled, therapeutic blockade or upregulation may be possible.
Ward
P A
PA
Department of Pathology, University of Michigan Medical School, Ann Arbor, USA.
D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000276:immunology / Q000628:therapy; D001327:Autoimmune Diseases / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D016207:Cytokines / Q000276:immunology*; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology / Q000276:immunology / Q000628:therapy; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000276:immunology* / Q000628:therapy
D016207:Cytokines