[Alanine aminotransferase--a surrogate marker of viral hepatitis].
Examinations of 4457 blood donors (about 80% were men aged 18 to 30) revealed an increased level of serum glutamic-pyruvic transaminase (SGPT) in 82 (1.8%). Specific markers of viral hepatitis C were detected in 15.9%, of hepatitis B in 12.0%, of hepatitis D in 2.0%, of hepatitis E in 8.0%, of hepatitis A in 2.0% of sera with high SGPT levels. Mandatory screening of blood donors revealed specific markers of viral hepatitis in 15.9% of cases, additional testing detected these markers in 10.9% cases more. A conclusion is made that an increase of SGPT activity is an independent surrogate marker of viral hepatitis.
Zhiburt
E B
EB
Bel'gesov
N V
NV
Vashchenko
T N
TN
Bondarenko
I G
IG
Tokmakov
V S
VS
Vasiliuk
V B
VB
D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000032:analysis*; D015415:Biomarkers / Q000032:analysis*; D006505:Hepatitis / Q000201:enzymology*; D006801:Humans; D008297:Male
D015415:Biomarkers; D000410:Alanine Transaminase
Alaninaminotransferaza--surrogatnyĭ marker virusnogo gepatita.