title: Therapeutic approaches for memory impairments.
abstract: Pharmacological treatment strategies for the treatment in dementia disorders were described. A selection of the 15 different classes described by Fröstl and Maitre was made. In the paper there were included and described in detail the following classes: piracetam-type compounds, co-dergocrine-type compounds, vasodilators and haemorheological agents, cholinesterase inhibitors, ACTH and vasopressin analogs and angiotensin II and angiotensin converting enzyme inhibitors. Some compounds e.g. propentofylline, vincamine, THA and RA-octil were described in more detail.
authors.affiliation: HOECHST AG, General Pharmacology Research, Pharmacological Screening, Frankfurt/M., Germany.
authors.forename: F J
authors.initials: FJ
authors.lastname: Hock
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000503:physiopathology; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D002491:Central Nervous System Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003704:Dementia / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D011939:Mental Recall / Q000187:drug effects* / Q000502:physiology; D012153:Retention, Psychology / Q000187:drug effects* / Q000502:physiology
chemical_list: D002491:Central Nervous System Agents