Ca2+ ion transport through patch-clamped cells exposed to magnetic fields.
The total current of Ca2+ ions through patch-clamped cell membranes was measured while exposing clonal insulin-producing beta-cells (RINm5F) to a combination of DC and AC magnetic fields at so-called cyclotron resonance conditions. Previous experimental evidence supports the theory that a resonant interaction between magnetic fields and organisms can exist. This experiment was designed to test one possible site of interaction: channels in the cell membrane. The transport of Ca2+ ions through the protein channels of the plasma membrane did not show any resonant behavior in the frequency range studied.
Höjevik
P
P
Department of Microwave Technology, Chalmers University of Technology, Göteborg, Sweden.
Sandblom
J
J
Galt
S
S
Hamnerius
Y
Y
D007516:Adenoma, Islet Cell / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000493:pharmacokinetics; D015220:Calcium Channels / Q000528:radiation effects*; D002462:Cell Membrane / Q000378:metabolism / Q000528:radiation effects; D004574:Electromagnetic Fields; D017136:Ion Transport / Q000528:radiation effects*; D007515:Islets of Langerhans / Q000378:metabolism / Q000528:radiation effects; D008564:Membrane Potentials; D018408:Patch-Clamp Techniques; D051381:Rats; D014407:Tumor Cells, Cultured
D015220:Calcium Channels; D002118:Calcium