[Interaction between 4-hydroxynonenane with membrane system. 1H, 31P, 2H NMR study].
The interactions between membranes and 4-hydroxynonenane (HNE)-a natural product of polyinsatured fatty acids peroxidation-were investigated by NMR spectroscopies. This molecule is located in the intermediate part of the bilayer. The presence of the HNE induces an increase of the fluidity in the deep part of the membrane, while a rigidification of the superficial part is found.
Heintz
O
O
CRSSA, unité de Biophysique, La Tronche.
Bossanne
P
P
Fauvelle
F
F
Debouzy
J C
JC
D000447:Aldehydes / Q000494:pharmacology*; D003903:Deuterium; D006859:Hydrogen; D008051:Lipid Bilayers / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008566:Membranes / Q000737:chemistry / Q000187:drug effects; D008567:Membranes, Artificial; D010758:Phosphorus
D000447:Aldehydes; D008051:Lipid Bilayers; D008567:Membranes, Artificial; D010758:Phosphorus; D006859:Hydrogen; D003903:Deuterium; C027576:4-hydroxy-2-nonenal
Interaction du 4-hydroxynonénane avec les systèmes membranaires. Etude RMN du 1H, 31P et 2H.