title: Immunohistochemical characterisation of probable intravascular haematopoiesis in the vasa rectae of the renal medulla in acute tubular necrosis.
abstract: Immunohistochemistry was applied to identify the nature of the nucleated cells that accumulate in the vasa rectae of the corticomedullary junction in acute tubular necrosis. In all 6 cases studied, there were intravascular cells that reacted with monoclonal antibodies to erythroblast, macrophages, myeloid cells, T and B lymphocytes and rare megakaryocytes. The findings are consistent with the occurrence of intravascular haematopoiesis in the renal medulla in acute tubular necrosis.
authors.affiliation: Department of Pathology, School of Medicine, UNESP, Brazil.
authors.forename: C E
authors.initials: CE
authors.lastname: Bacchi
authors.forename: N
authors.initials: N
authors.lastname: Rocha
authors.forename: M
authors.initials: M
authors.lastname: Carvalho
authors.forename: D
authors.initials: D
authors.lastname: Schmitt
authors.forename: F
authors.initials: F
authors.lastname: Schmitt
authors.forename: M
authors.initials: M
authors.lastname: Franco
mesh_terms: D000328:Adult; D000368:Aged; D001160:Arterioles / Q000473:pathology; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D007124:Immunoenzyme Techniques; D007679:Kidney Medulla / Q000098:blood supply* / Q000473:pathology; D007683:Kidney Tubular Necrosis, Acute / Q000473:pathology* / Q000503:physiopathology*; D008875:Middle Aged