title: Purification and some properties of a hydrophilic prokallikrein and a hydrophobic prokallikrein from sheep kidney cortex.
abstract: 1. A hydrophilic and a hydrophobic prokallikrein were purified from sheep kidney cortex and some of their biochemical properties were compared. 2. The effects of several inhibitors on the activity of the hydrophilic and hydrophobic kallikreins were investigated. 3. The thermal stability and response of the hydrophobic kallikrein towards various detergents were also studied.
authors.affiliation: Department of Chemistry and Biological Chemistry, University of Essex, Colchester, UK.
authors.forename: L S
authors.initials: LS
authors.lastname: Bilbis
authors.forename: R A
authors.initials: RA
authors.lastname: Shehu
authors.forename: M A
authors.initials: MA
authors.lastname: al-Tufail
authors.forename: A M
authors.initials: AM
authors.lastname: al-Joufi
authors.forename: G S
authors.initials: GS
authors.lastname: Bailey
mesh_terms: D000818:Animals; D002845:Chromatography; D003902:Detergents / Q000494:pharmacology; D004792:Enzyme Precursors / Q000302:isolation & purification* / Q000378:metabolism; D007610:Kallikreins / Q000302:isolation & purification* / Q000378:metabolism; D007672:Kidney Cortex / Q000201:enzymology*; D007705:Kinins / Q000494:pharmacology; D012756:Sheep; D013997:Time Factors
chemical_list: D003902:Detergents; D004792:Enzyme Precursors; D007705:Kinins; D007610:Kallikreins; C052910:prokallikrein, tissue