Potentiometric determination of ephedrine hydrochloride using plastic membrane ion-selective electrode.
A plastic membrane electrode based on phenylephrine-tetraphenylborate ion association shows a Nernstian response to both ephedrinium (Ep+) and silver (Ag+) cations over the concentration ranges 2 x 10(-5)-10(-1) M and 10(-5)-10(-1) M for Ep+ and Ag+, respectively. The performance characteristics of the electrode were investigated. The electrode proved to be an excellent potentiometric sensor for the determination of Ep-hydrochloride in its pure solutions and pharmaceutical preparations using the extrapolation method and potentiometric titration using a standard solution of AgNO3.
Zareh
M M
MM
Chemistry Department, Faculty of Science, Zagazig University, Egypt.
Issa
Y M
YM
Shoukry
A F
AF
Shohaib
R E
RE
D004563:Electrochemistry / Q000379:methods; D004809:Ephedrine / Q000032:analysis* / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D017736:Ion-Selective Electrodes; D008567:Membranes, Artificial; D010969:Plastics; D011143:Polyvinyl Chloride; D011199:Potentiometry; D013775:Tetraphenylborate / Q000737:chemistry
D008567:Membranes, Artificial; D010969:Plastics; D013775:Tetraphenylborate; D011143:Polyvinyl Chloride; D004809:Ephedrine