Living-related liver transplantation in adult recipients: a hypothesis.
Living-related liver transplantation (LRLT) in pediatric recipients has been successful with 90% 1-year survival (1, 2). LRLT in adults is yet to succeed. We hypothesize a management strategy based on the donor graft weight-to-recipient body weight ratio (GRBWR) and the Redox Tolerance Index (RTI) (3). Favorable recipients (GRBWR above 0.7%) are candidates for left liver orthotopic transplantation. Unfavorable recipients (GRBWR 0.5-0.7% and RTI above 0.5%) are suitable for left liver auxiliary-orthotopic transplantation. Compromized recipients (GRBWR below 0.5% or RTI below 0.5%) might be suitable for a left liver auxiliary-heterotopic transplantation. The above hypothesis remains to be validated.
Habib
N
N
Department of Surgery, Hammersmith Hospital, Royal Postgraduate Medical School, London, UK.
Tanaka
K
K
D000328:Adult; D001835:Body Weight; D002648:Child; D006085:Graft Survival; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008099:Liver / Q000033:anatomy & histology; D016031:Liver Transplantation / Q000379:methods* / Q000401:mortality; D009929:Organ Size; D010084:Oxidation-Reduction; D015996:Survival Rate; D014019:Tissue Donors; D016042:Transplantation, Heterotopic