title: The effect of L-carnitine, administered through intravenous infusion of glucose, on both glucose and insulin levels in healthy subjects.
abstract: The goal of the present study was to evaluate the effect of L-carnitine on plasma glucose and insulin levels. Two parallel studies were set-up, of 40 and 20 healthy volunteers, respectively. Each group received 500 cc of 10% glucose or 5% glucose, to which were randomly added 4 g or 2 g of L-carnitine and administered a week apart. Results showed that L-carnitine was able to reduce the increase in glucose plasma levels induced by infusion of the glucose solution. This finding was not dependent on an insulin-dependent mechanism.
authors.affiliation: Polyclinic Umberto I, University La Sapienza, Rome, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Negro
authors.forename: F
authors.initials: F
authors.lastname: Gossetti
authors.forename: M
authors.initials: M
authors.lastname: La Pinta
authors.forename: P
authors.initials: P
authors.lastname: Mariani
authors.forename: M
authors.initials: M
authors.lastname: Carboni
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D002331:Carnitine / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007262:Infusions, Intravenous; D007328:Insulin / Q000097:blood*; D008297:Male
chemical_list: D001786:Blood Glucose; D007328:Insulin; D005947:Glucose; D002331:Carnitine