Polyserositis in adult Still's disease with onset during pregnancy [corrected].
We report about a 25-year-old female patient, who met all the criteria of adult-onset Still's disease except for the typical nonpruric rash. The disease exacerbated during pregnancy. Polyserositis was the predominant clinical manifestation. The histological examination of the bone marrow biopsy revealed changes similar to those seen in a myelodysplastic syndrome. The clinical condition improved after therapy with high-dose steroids and cyclophosphamide.
Falkenbach
A
A
Johann Wolfgang Goethe-University Hospital, Frankfurt am Main, FRG.
Lembcke
B
B
Schneider
M
M
Wigand
R
R
Mulert-Ernst
R
R
Caspary
W
W
D000032:Abortion, Therapeutic; D000328:Adult; D001856:Bone Marrow Examination; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D011261:Pregnancy Trimester, First; D012700:Serositis / Q000150:complications*; D016706:Still's Disease, Adult-Onset / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy
D003520:Cyclophosphamide; D011241:Prednisone