Selenium deficiency and decreased coenzyme Q levels.
The effect of long-term (18 months) selenium deficiency on the levels of liver coenzyme Q was studied in the rat. Levels of coenzyme Q9 and coenzyme Q10 in the liver of selenium-deficient rats were 40 and 67% of the levels in selenium-adequate animals, respectively. The results are similar to the findings using a shorter feeding period.
Vadhanavikit
S
S
Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston 77555, USA.
Ganther
H E
HE
D000818:Animals; D003067:Coenzymes; D005982:Glutathione Transferase / Q000378:metabolism; D007453:Iodide Peroxidase / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012643:Selenium / Q000172:deficiency* / Q000502:physiology; D013963:Thyroid Hormones / Q000097:blood; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000378:metabolism*
D003067:Coenzymes; D013963:Thyroid Hormones; D014451:Ubiquinone; D007453:Iodide Peroxidase; D005982:Glutathione Transferase; C024989:coenzyme Q10; D012643:Selenium; C030571:ubiquinone 9