title: [Second tumors in childhood].
abstract: More aggressiveness in treatment of childhood malignancies has had an evident impact on survival and rate of cure but, it has also allowed us to discover long-term effects of these treatments, and second malignant tumors of them. Between 1970 and 1993, 472 cases of malignant tumors in childhood were diagnosed in our department. Six of them (1.27%) developed a second tumor (five malignant and one benign). Relationship between first and second tumors are: seven years old boy, cervical lymphosarcoma-thyroid carcinoma; eleven years old boy, osteogenic sarcoma-vesical carcinoma: two years and six months old boy, cerebellar astrocytoma-soft tissue osteogenic sarcoma; five years old girl. Wilm's tumor-scapular osteogenic chondroma; one year and a half old girl, abdominal neuroblastoma-granulocytic sarcoma (chloroma); twelve years old boy. Hodgkin's disease-acute myeloblastic leukemia. All of them were clearly related to concogenic effect of radiation or chemotherapy.
authors.affiliation: Servicio de Cirugía Pediátrica, Hospital General Universitario Gregorio Marañón, Madrid.
authors.forename: J A
authors.initials: JA
authors.lastname: Navascués
authors.forename: C
authors.initials: C
authors.lastname: Estellés
authors.forename: E
authors.initials: E
authors.lastname: Molina
authors.forename: R
authors.initials: R
authors.lastname: Martín Crespo
authors.forename: J
authors.initials: J
authors.lastname: Cerdá
authors.forename: F
authors.initials: F
authors.lastname: Aguilar
authors.forename: A
authors.initials: A
authors.lastname: Cantalejo
mesh_terms: D000008:Abdominal Neoplasms; D001254:Astrocytoma; D001859:Bone Neoplasms; D002277:Carcinoma; D002528:Cerebellar Neoplasms; D002648:Child; D002675:Child, Preschool; D002812:Chondroma; D005260:Female; D006258:Head and Neck Neoplasms; D006689:Hodgkin Disease; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms; D007951:Leukemia, Myeloid; D015470:Leukemia, Myeloid, Acute; D008228:Lymphoma, Non-Hodgkin; D008297:Male; D016609:Neoplasms, Second Primary; D009447:Neuroblastoma; D012516:Osteosarcoma; D012540:Scapula; D012983:Soft Tissue Neoplasms; D013964:Thyroid Neoplasms; D013997:Time Factors; D001749:Urinary Bladder Neoplasms; D009396:Wilms Tumor
vernacular_title: Segundos tumores en la infancia.