title: Genotoxic effects of deltamethrin in the mouse bone marrow micronucleus assay.
abstract: The genotoxicity of deltamethrin was studied in Swiss albino male mice (five animals/group) using the bone marrow micronucleus assay. Deltamethrin (two i.p. injections, 30 h and 6 h before sample collection) was found to induce micronuclei at 162.5 and 300.0 mg/kg body weight. A lower dose (32.5 mg/kg body weight) failed to induce a significant increase in micronuclei over the control level.
authors.affiliation: Department of Human Genetics, Guru Nanak Dev University, Amritsar, India.
authors.forename: G
authors.initials: G
authors.lastname: Gandhi
authors.forename: J B
authors.initials: JB
authors.lastname: Chowdhury
authors.forename: P K
authors.initials: PK
authors.lastname: Sareen
authors.forename: V P
authors.initials: VP
authors.lastname: Dhillon
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D051379:Mice; D015162:Micronucleus Tests; D009570:Nitriles; D011722:Pyrethrins / Q000633:toxicity*
chemical_list: D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin