title: Intermittent subobstruction and cholestasis as complications of duodenal amyloid tumours.
abstract: Amyloidosis confined to the duodenum is uncommon. In the present report the history of an 83-year old patient, admitted for vomiting and heavy epigastric pain, is described. Radiographic and endoscopic investigation revealed two polypoid lesions in the duodenum (D2). Biopsies showed diffuse amyloid deposition in the lamina propria, muscularis mucosae and submucosa of the duodenum as well as vascular deposits. No other localisations were documented. Amyloid tumours of the gastrointestinal tract are rare but may lead to serious symptoms.
authors.affiliation: Department of Pathology II, UZ St Rafaël, Catholic University Leuven, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Baldewijns
authors.forename: N
authors.initials: N
authors.lastname: Ectors
authors.forename: G
authors.initials: G
authors.lastname: Verbeeck
authors.forename: J
authors.initials: J
authors.lastname: Janssens
authors.forename: J
authors.initials: J
authors.lastname: De Schepper
authors.forename: E
authors.initials: E
authors.lastname: Ponette
authors.forename: K
authors.initials: K
authors.lastname: Geboes
authors.forename: V
authors.initials: V
authors.lastname: Desmet
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000686:Amyloidosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002779:Cholestasis / Q000209:etiology*; D004378:Duodenal Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D004379:Duodenal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D004380:Duodenal Obstruction / Q000150:complications / Q000209:etiology*; D006801:Humans; D008297:Male; D011127:Polyps / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed