title: [Allogenic bone marrow transplantation in Wiskott-Aldrich syndrome].
abstract: Two males of 3 and 3 1/2 years of age with the Wiskott-Aldrich syndrome who underwent bone marrow transplantation from an HLA compatible brother following conditioning treatment with busulphan and cyclophosphamide are described. In both patients the taking of the graft was proven by study of blood subgroups and correction of the immunodeficiency, normalization of platelet number and function and disappearance of cutaneous eczema were seen. At 3 and 1 year respectively of the transplantation the patients showed no evidence of graft versus host disease and no severe infections or hemorrhagic episodes have seen.
authors.affiliation: Servicio de Pediatría, Hospital Ramón y Cajal, Madrid.
authors.forename: M S
authors.initials: MS
authors.lastname: Maldonado
authors.forename: A
authors.initials: A
authors.lastname: Muñoz
authors.forename: E
authors.initials: E
authors.lastname: Otheo de Tejada
authors.forename: E
authors.initials: E
authors.lastname: Roldán
authors.forename: L
authors.initials: L
authors.lastname: Aymerich
authors.forename: J A
authors.initials: JA
authors.lastname: Brieva
mesh_terms: D016026:Bone Marrow Transplantation; D002675:Child, Preschool; D006801:Humans; D008297:Male; D014923:Wiskott-Aldrich Syndrome / Q000601:surgery*
vernacular_title: Trasplante de medula ósea alogénico en el síndrome de Wiskott-Aldrich.