Transcription factor based therapeutics: drugs of the future?
During the past decade there has been an explosion of information relating to our understanding of eukaryotic gene expression. The identification of transcription factors as the key regulatory molecules in this process, and the analysis of their structure and function have revealed that these proteins are potential targets for therapeutic intervention.
Peterson
M G
MG
Tularik, Inc., South San Francisco, CA 94080.
Baichwal
V R
VR
D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D015195:Drug Design; D004358:Drug Therapy; D005786:Gene Expression Regulation / Q000187:drug effects*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics; D014157:Transcription Factors / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D014158:Transcription, Genetic / Q000187:drug effects
D004268:DNA-Binding Proteins; D014157:Transcription Factors