Pneumonia complicating adult respiratory distress syndrome.
Aspiration bronchopneumonia occurs in most patients undergoing prolonged mechanical ventilation. These pneumonias adversely affect lung function and release bacteria into the systemic circulation via the lungs' lymphatics. Through this mechanism, clinically occult pneumonias may initiate activation of systemic inflammation, leading to the syndrome of multiple organ failure.
Dever
L L
LL
University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, USA.
Johanson
W G
WG
D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D010215:Papio; D018410:Pneumonia, Bacterial / Q000150:complications* / Q000276:immunology / Q000382:microbiology; D012128:Respiratory Distress Syndrome / Q000150:complications* / Q000276:immunology / Q000503:physiopathology