Nuclear disintegration in chicken peritoneal macrophages exposed to fumonisin B1 from Indian maize.
The effects of fumonisin B1 (FB1) on the morphology of chicken peritoneal macrophages were studied. It was found that FB1-exposure caused nuclear disintegrations in peritoneal macrophages. The number of macrophages experiencing nuclear disintegration increased with the rise in the dose of FB1 from 6 to 18 micrograms ml-1. The finding implies that dietary intake of FB1 may damage the macrophages in consumers rendering the latter susceptible to infection.
Chatterjee
D
D
Department of Food Technology and Biochemical Engineering, Jadavpur University, Calcutta, India.
Mukherjee
S K
SK
Dey
A
A
D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects*; D002645:Chickens; D005260:Female; D037341:Fumonisins; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000648:ultrastructure*; D009183:Mycotoxins / Q000494:pharmacology*; D003313:Zea mays / Q000382:microbiology
D037341:Fumonisins; D009183:Mycotoxins; C056933:fumonisin B1