title: Alcohol intoxication in childhood and adolescence.
abstract: Coma and vomiting are the commonest symptoms in young teenagers intoxicated by alcohol. Severe toxicity, manifested as coma, occurs at lower blood alcohol concentrations in young teenagers than in adults. The effect of ethanol on the state of consciousness is directly proportional to blood alcohol concentration. Among children under 5 years of age the risk of hypoglycaemia is increased. A significant risk in acute alcohol intoxication is the rapid development of coma, which in cold environments could lead to fatal hypothermia. Preschool-age children are reported to eliminate ethanol twice as fast as adults, whereas young teenagers eliminate it at the adult rate. The biochemical disturbances in children 11 to 16 years of age with alcohol intoxication resemble those of adults. Mild acidosis of a respiratory or metabolic origin and mild hypokalaemia are common findings in young teenagers. Fluid replacement with glucose-containing fluids and follow-up are generally the only treatments needed for complete recovery. Motives leading to alcohol intoxication are a wish to get drunk, experimenting, problems in human relations, and attempted suicide. The underlying problems are often family-related, such as divorce, an alcoholic parent and a lower socioeconomic group.
authors.affiliation: Department of Clinical Pharmacology, University of Helsinki, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Lamminpää
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000428:Alcohol Drinking; D000437:Alcoholism / Q000150:complications* / Q000378:metabolism; D002648:Child; D002652:Child Behavior; D002675:Child, Preschool; D003244:Consciousness Disorders / Q000209:etiology; D000431:Ethanol / Q000097:blood / Q000378:metabolism; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology; D007035:Hypothermia / Q000209:etiology; D007223:Infant; D008107:Liver Diseases / Q000209:etiology / Q000378:metabolism; D008297:Male; D012737:Sex Factors; D014882:Water-Electrolyte Balance
chemical_list: D000431:Ethanol