[Effects of propofol in patients in status epilepticus of various origins. Electroencephalographic analysis].
The authors discuss the effect of propofol administered to epileptic patients in intensive care. Several reports have attributed and antiepileptic effect to this drug, whereas a similar number have correlated it to epileptogenic manifestations of various types. Three "typical" cases of epilepsy were studied: chronic postoperative, chronic and acute post-traumatic. EEG patterns were analysed following continuous administration, using a bolus and using varying doses of the drug itself. Propofol appears to modify EEG patterns in a positive manner and is therefore confirmed as being useful in the sedation of epileptic patients in intensive care.
Mazzarino
A
A
Cattedra di Anestesia e Rianimazione, Università degli Studi, Brescia.
De Maria
G
G
Candiani
A
A
D000328:Adult; D004569:Electroencephalography / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015742:Propofol / Q000494:pharmacology*; D013226:Status Epilepticus / Q000209:etiology / Q000503:physiopathology*
D015742:Propofol
Effetti del propofol in pazienti in stato di male epilettico di varia origine. Analisi elettroencefalografica.