title: Structure and function of titin and nebulin.
abstract: Recent investigations of titin anchorage and elasticity have been supplemented with in vitro expression studies on isolated domains of titin and nebulin. These have yielded new insights into the molecular basis of the functions of these proteins in muscle. The characterization of a cellular (non-muscle) isoform of titin has extended the functional relevance of this family of proteins beyond the realm of muscle.
authors.affiliation: Department of Biological Science, Florida State University, Tallahassee 32306-3050, USA.
authors.forename: T C
authors.initials: TC
authors.lastname: Keller
mesh_terms: D000818:Animals; D064211:Connectin; D009124:Muscle Proteins / Q000737:chemistry* / Q000502:physiology; D009210:Myofibrils / Q000502:physiology; D009218:Myosins / Q000032:analysis; D011494:Protein Kinases; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship
chemical_list: D064211:Connectin; D009124:Muscle Proteins; C035620:nebulin; D011494:Protein Kinases; D009218:Myosins