title: Genetic modulation in the pathogenesis and treatment of cancer.
abstract: Recent advances in molecular biology have improved our understanding of the pathogenesis of cancer. Molecular genetic alterations have been characterized in lung and esophageal tumors, and have potential clinical application in tumor diagnosis, staging, prevention, and therapy.
authors.affiliation: Department of Surgery, University of Toronto Faculty of Medicine, Ontario, Canada.
authors.forename: A G
authors.initials: AG
authors.lastname: Casson
authors.forename: J A
authors.initials: JA
authors.lastname: McCart
mesh_terms: D004273:DNA, Neoplasm / Q000032:analysis; D004938:Esophageal Neoplasms / Q000209:etiology / Q000235:genetics* / Q000628:therapy; D016147:Genes, Tumor Suppressor / Q000235:genetics; D005815:Genetic Code; D005819:Genetic Markers; D005821:Genetic Techniques; D015316:Genetic Therapy; D006801:Humans; D009369:Neoplasms / Q000209:etiology / Q000235:genetics* / Q000628:therapy; D009857:Oncogenes / Q000235:genetics
chemical_list: D004273:DNA, Neoplasm; D005819:Genetic Markers