title: [Immune system in pregnant women exposed to extreme climate conditions of the Aral coast line].
abstract: Fifty-eight women aged 18 to 38 with preserved reproductive function were examined, 42 of them with a normal course of gestation and 16 nonpregnant ones. Cellular and humoral immunity parameters were studied: absolute and relative counts of T-lymphocytes and levels of serum IgA, IgG, and IgM. The immunity status of women living near the Aral sea was changed: the absolute and relative counts of T-lymphocytes were reduced in both groups. Pregnant women had a trend to reduction of T-lymphocyte count in the first gestation trimester and a reliable increase of the levels of T-lymphocytes and theophyllin-sensitive cells in the third trimester (p < 0.001). The lowest counts of T-lymphocytes and theophyllin-sensitive cells were observed in primigravidas vs. multigravidas and multiparas.
authors.forename: O A
authors.initials: OA
authors.lastname: Atanizova
authors.forename: N K
authors.initials: NK
authors.lastname: Matveeva
authors.forename: A B
authors.initials: AB
authors.lastname: Kurbanov
authors.forename: Ch A
authors.initials: ChA
authors.lastname: Abdirov
authors.forename: I V
authors.initials: IV
authors.lastname: Ponomareva
mesh_terms: D000293:Adolescent; D000328:Adult; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D007074:Immunoglobulin G / Q000276:immunology*; D007075:Immunoglobulin M / Q000276:immunology*; D018655:Lymphocyte Count; D011247:Pregnancy / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D014610:Uzbekistan
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Kharakteristika immunnoĭ sistemy u beremennykh zhenshchin, prozhivaiushchikh v ékstremalńykh usloviiakh Priaralía.