title: [Familial pituitary tumor with somatotropic compromise].
abstract: Pituitary adenoma, familiar type, with apparent affection over the involved somatomammotropin of secretion of growth hormone and prolactin, with dominant autosomic transmission, is described for the first time. It was seen that a couple of members without demonstrable tumour, showed clinical data (phenotype) of acromegaly. On investigation of histocompatibility antigens it was observed that the patients with tumour and other symptomatic ones, but without tumour, shared the same haplotypes, and so is very possible that investigation of HLA antigens in patients with pituitary tumour, contributes to better identify its nature and frequency.
authors.affiliation: Dirección de Investigación y Enseñanza, Hospital Juárez de Méxco, SSA. México, D.F.
authors.forename: A R
authors.initials: AR
authors.lastname: Ayala Ruiz
authors.forename: D
authors.initials: D
authors.lastname: Delgado Ochoa
authors.forename: M D
authors.initials: MD
authors.lastname: Vergara
authors.forename: M
authors.initials: M
authors.lastname: Loyo
authors.forename: A
authors.initials: A
authors.lastname: Matute Labrador
authors.forename: L
authors.initials: L
authors.lastname: Rosas
authors.forename: I
authors.initials: I
authors.lastname: Hernández Marín
authors.forename: R
authors.initials: R
authors.lastname: Cervera Aguilar
mesh_terms: D000172:Acromegaly / Q000150:complications / Q000235:genetics*; D000236:Adenoma / Q000150:complications / Q000235:genetics*; D000328:Adult; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006239:Haplotypes; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010911:Pituitary Neoplasms / Q000150:complications / Q000235:genetics*
chemical_list: D006680:HLA Antigens
vernacular_title: Tumor hipofisario familiar de compromiso somatomamotrópico.