title: Incidence, species distribution and antifungal sensitivity pattern of vaginal yeasts in Sri Lankan women.
abstract: A total of 432 high vaginal swabs from patients with vulvovaginitis were processed for the presence of yeasts. Candida species were isolated from 40 (32.4%). In comparison, vaginal swabs from 107 normal asymptomatic women yielded only eight (7.3%) isolates (P < 0.001). Candida albicans was the commonest species isolated (76%). Other species included C. tropicalis, C. krusei, C. kefyr, C. glabrata and C. guilliermondii. Of the C. albicans isolates, 42.8% showed in vitro resistance to miconazole and 6.6% to econazole. Ninety-two percent of the isolates were sensitive to the polyenes (nystatin and amphotericin B) and 87% and 74% to clotrimazole and ketaconazole respectively.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Colombo, Sri Lanka.
authors.forename: J
authors.initials: J
authors.lastname: Perera
authors.forename: Y
authors.initials: Y
authors.lastname: Clayton
mesh_terms: D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D015994:Incidence; D008826:Microbial Sensitivity Tests; D011446:Prospective Studies; D013188:Sri Lanka / Q000453:epidemiology; D014627:Vaginitis / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents