[Adrenergic and cholinergic regulation of respiratory efficiency of secretory cells].
The influence of sympathetic and parasympathetic systems on the secretory cell respiration is mediated at the subcellular level by adreno- and cholinoreceptors of plasmatic membranes and is related to selective oxidation of two different substrates of the Krebs cycle: succinate and alpha-ketoglutarate, both being involved into two reciprocal mediator-hormonal-substrate-nucleotide systems: catecholamines-succinate-cAMP-ATP and acetylcholint-alpha-ketoglutarate-cGMP-GTP. The reciprocation of these systems is necessary for regulation of cell oxygen demand and effective oxygen utilization for ATP-synthesis and synthesis of other macroergical compounds depending on the functional state of a cell.
Hordiĭ
S K
SK
Shostakovska
I V
IV
Doliba
M M
MM
Babskyĭ
A M
AM
Muzyka
F V
FV
Kondrashova
M M
MM
Stefankiv
Iu S
IuS
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D002952:Citric Acid Cycle; D000242:Cyclic AMP / Q000378:metabolism; D006801:Humans; D007413:Intestinal Mucosa / Q000166:cytology / Q000378:metabolism*; D007421:Intestine, Small / Q000166:cytology / Q000378:metabolism*; D007656:Ketoglutaric Acids / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D010101:Oxygen Consumption; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011950:Receptors, Cholinergic / Q000378:metabolism*; D013386:Succinates / Q000378:metabolism; D019802:Succinic Acid
D007656:Ketoglutaric Acids; D011941:Receptors, Adrenergic; D011950:Receptors, Cholinergic; D013386:Succinates; D000255:Adenosine Triphosphate; D019802:Succinic Acid; D000242:Cyclic AMP
Adrenerhichni ta kholinerhichni mekhanizmy rehuliatsiĭ efektyvnosti dykhannia sekretornykh klityn.