title: [Clinical bacteriological analysis of Vibrio vulnificus infection--a report of five case].
abstract: Clinical features in Vibrio infection are generally represented by gastrointestinal involvements such as food poisoning, and its prognosis is usually good. However, Vibrio vulnificus infection not uncommonly causes serious problems including sepsis, necrotizing fasciitis of the extremities, and other conditions, sometimes resulting in fatal outcome. In the present study, we analyzed clinical microbiological aspects of five cases with V. vulnificus infection. All the strains of V. vulnificus isolated in five patients are oxidase-positive Gram negative rods presenting comma-like configuration, which were yielded on TCBS agar forming green colonies; they were grayish-white in color and viscous in texture on 5% sheep blood agar, identification of bacteria were done using VITEK AMS (BioMérieux). Piperacillin and third-generation cephalosporins were found to have bactericidal activities against these strains. All five cases we experienced have primary ailments, and three cases out of the five had taken perishable sea-food before showing disease symptoms. V. vulnificus has two infection channels; one is external wound and the other is oral intake. The latter is said that it may become serious. This has a rather short period from the starting the symptoms to death, and there is high death rate. For life-saving, it is inevitably necessary to dose an effective antibacterial medicine in the early stage. If we suspect this bacteria in the test laboratory, it is important to report this to the clinical doctor. In other words, this is one of the bacteria that needs prompt treatment and further microbiology testing.
authors.affiliation: Department of Laboratory Medicine, Saga Medical School Hospital.
authors.forename: I
authors.initials: I
authors.lastname: Tanabe
authors.forename: K
authors.initials: K
authors.lastname: Kusaba
authors.forename: Z
authors.initials: Z
authors.lastname: Nagasawa
authors.forename: Y
authors.initials: Y
authors.lastname: Tajima
authors.forename: J
authors.initials: J
authors.lastname: Tadano
authors.forename: N
authors.initials: N
authors.lastname: Fujisawa
authors.forename: H
authors.initials: H
authors.lastname: Yamada
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D014733:Vibrio / Q000187:drug effects / Q000302:isolation & purification; D014735:Vibrio Infections / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents