Amino acid sequence of natural tumor necrosis factor alpha inhibitor purified from human urine.
Tumor necrosis factor alpha inhibitor (TNF-INH) was purified from human urine and it was composed of 161 amino acid residues. The complete amino acid sequence of TNF-INH found by sequence analysis agreed with that predicted from the cDNA structure for the extracellular domain (1-161 portion) of 55-kDa TNF receptor and its processing site at the C-terminal was Asn-161.
Kajihara
J
J
Biochemistry Research Laboratories, JCR Pharmaceuticals Co., Ltd., Kobe, Japan.
Asada
A
A
Kirihara
S
S
Kato
K
K
D000595:Amino Acid Sequence; D002852:Chromatography, Ion Exchange; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D008969:Molecular Sequence Data; D014409:Tumor Necrosis Factor-alpha / Q000737:chemistry* / Q000652:urine
D014409:Tumor Necrosis Factor-alpha