title: Extensive wound excision in the acute shock stage in patients with major burns.
abstract: In order to reduce excessive plasma loss, to alleviate the effects of devitalized tissues on the body, and to shorten the time in hospital, we attempted to perform extensive escharectomy during the shock period in extensively burned patients. Group A consisted of 21 patients, aged 9-45 years, with a mean total burn area of 63.2 +/- 18.1 per cent TBSA, and full-thickness injury involving 35.9 +/- 19.6 per cent TBSA. The first escharectomy was performed at 24.1 +/- 13.9 h postburn. The excision area averaged 32.3 +/- 6.7 per cent TBSA (range 24-96 per cent). In 15 patients a Swan-Ganz catheter was introduced to monitor haemodynamic changes. It was found that RAP, PAP, PAWP, ABP, HR, CO and CI were all stable during and after the operation. Group B consisted of 29 patients, and escharectomy was begun 4-5 days postburn. The mean healing time of the patients in group A was 33.1 days, which was shorter than that in group B (40.1 days). The period of haemoconcentration was shorter in group A and the amount of blood required during the first 2 weeks was almost 700 ml less in group A. There were fewer visceral complications in group A and smaller amounts of antibiotics were required in this group. The authors believe that escharectomy during the shock stage is feasible.
authors.affiliation: Trauma Center, 304th Hospital, Postgraduate Medical College of PLA, China.
authors.forename: Z R
authors.initials: ZR
authors.lastname: Guo
authors.forename: C Y
authors.initials: CY
authors.lastname: Sheng
authors.forename: L
authors.initials: L
authors.lastname: Diao
authors.forename: W Y
authors.initials: WY
authors.lastname: Gao
authors.forename: H M
authors.initials: HM
authors.lastname: Yang
authors.forename: H Y
authors.initials: HY
authors.lastname: Lin
authors.forename: J L
authors.initials: JL
authors.lastname: Han
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001803:Blood Transfusion; D002056:Burns / Q000097:blood / Q000150:complications / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006439:Hemodynamics; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D011182:Postoperative Care; D012774:Shock, Traumatic / Q000097:blood / Q000209:etiology / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy; D016038:Skin Transplantation; D013514:Surgical Procedures, Operative / Q000379:methods; D013997:Time Factors; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents