title: Supraglottic laryngectomy with or without postoperative radiotherapy in supraglottic carcinomas.
abstract: A retrospective review of 193 previously untreated patients with primary supraglottic carcinoma was undertaken to ascertain the efficacy of postoperative radiotherapy. All the patients received a supraglottic laryngectomy, and patients received a total of 284 elective or therapeutic neck dissections. Ninety-four (48.7%) of the patients received postoperative radiotherapy. The incidence of local recurrence was 8.2% but the recurrence rate was unrelated to the use of postoperative radiotherapy. Neck recurrence was observed in 12.9% of patients, with no influence of postoperative radiotherapy in the dissected neck. The incidence of locoregional recurrences by stage in irradiated and nonirradiated patients did not reach significant difference. The 3-year survival was 74.3%. The overall survival of the whole series and by stage was not statistically altered in combined therapy compared to surgery.
authors.affiliation: Department of Otolaryngology, Hospital Central de Asturias, University of Oviedo, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Suárez
authors.forename: J P
authors.initials: JP
authors.lastname: Rodrigo
authors.forename: J
authors.initials: J
authors.lastname: Herranz
authors.forename: J L
authors.initials: JL
authors.lastname: Llorente
authors.forename: J A
authors.initials: JA
authors.lastname: Martínez
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D005931:Glottis / Q000473:pathology / Q000528:radiation effects* / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D015996:Survival Rate