title: Persisting changes in the 24-hour profile of locomotor activity by daily activity restriction in rats.
abstract: Male Wistar rats were acclimated to cages with running wheels. Then, the running time of rats were limited to the last 3 (WR3) or 6 (WR6) h of the dark phase. After a 2-week activity restriction, the rats were again allowed access to the wheel freely. In the WR3 or WR6, wheel revolutions for the last 3 or 6 h of the dark phase was significantly greater after the activity restriction than before. The results suggest that, in rats, voluntary running limited to a fixed time daily alters the distributions of locomotor activity in a day, i.e., running activity increases during the period when the rats had been previously allowed to exercise.
authors.affiliation: Department of Physiology, School of Medicine, Kanazawa University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Sugimoto
authors.forename: O
authors.initials: O
authors.lastname: Shido
authors.forename: S
authors.initials: S
authors.lastname: Sakurada
authors.forename: T
authors.initials: T
authors.lastname: Nagasaka
mesh_terms: D000204:Activity Cycles; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D001835:Body Weight; D002940:Circadian Rhythm / Q000502:physiology*; D004435:Eating; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors