The Microspheres based Detoxification System (MDS). A new extracorporeal blood purification technology based on recirculated microspherical adsorbent particles.
Plasma sorption processes have so far been performed with filters and appropriate adsorption columns. In this paper, we introduce a newly developed plasma sorption system, which is based on the high adsorption capacity of microspheres in a recirculation system. The technology has been applied successfully in vitro to eliminate endotoxins, low density lipoproteins (LDL) and barbiturates from human plasma.
Weber
C
C
Interdisciplinary Institute of Bioengineering, Science Academy of Lower Austria, Krems.
Rajnoch
C
C
Loth
F
F
Schima
H
H
Falkenhagen
D
D
D000818:Animals; D001463:Barbiturates / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D004731:Endotoxins / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification; D008863:Microspheres; D011312:Pressure; D012015:Reference Standards; D016060:Sorption Detoxification / Q000592:standards* / Q000639:trends; D013552:Swine
D001463:Barbiturates; D004731:Endotoxins; D008077:Lipoproteins, LDL