The antimicrobial activity of phenoxyethanol in vaccines.
The activity of the antimicrobial preservatives, phenoxyethanol and thiomersal, were compared in diphtheria, tetanus and pertussis (adsorbed) vaccine. Both chemicals were equally effective in inactivating challenge doses of Gram-negative and Gram-positive micro-organisms, as well as a yeast.
Lowe
I
I
South African Institute for Medical Research (SAIMR), Serum and Vaccine Department, Sandringham.
Southern
J
J
D001419:Bacteria / Q000187:drug effects*; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D005026:Ethylene Glycols / Q000494:pharmacology*; D011310:Preservatives, Pharmaceutical / Q000494:pharmacology*; D013849:Thimerosal / Q000494:pharmacology*
D015721:Diphtheria-Tetanus-Pertussis Vaccine; D005026:Ethylene Glycols; D011310:Preservatives, Pharmaceutical; D013849:Thimerosal; C005398:phenoxyethanol