[The effect of reaferon and alpha-tocopherol on lipid peroxidation in experimental influenza].
Reaferon administered to outbred young mice with experimental influenza had a positive effect on morphologic changes in pulmonary tissues and on lipid peroxidation in the blood plasma and pulmonary tissues. Combined use of reaferon and alpha-tocopherol in mice infected with influenza A virus reduced the mortality rate, boosted the antiviral effect of reaferon proper, and led to virtually complete normalization of lipid peroxidation processes in the blood plasma and pulmonary tissues.
Pertseva
N G
NG
Ananenko
A A
AA
Malinovskaia
V V
VV
Klembovskiĭ
A I
AI
Burova
V Ia
VIa
Meshkova
E N
EN
Kleĭmenova
N V
NV
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology; D009980:Influenza A virus / Q000187:drug effects*; D007370:Interferon Type I / Q000494:pharmacology*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D015227:Lipid Peroxidation / Q000187:drug effects*; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000378:metabolism* / Q000821:virology; D011994:Recombinant Proteins; D014810:Vitamin E / Q000494:pharmacology*
D000998:Antiviral Agents; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D014810:Vitamin E
Vliianie reaferona i alpha-tokoferola na protsessy perekisnogo okisleniia lipidov pri éksperimental'noĭ grippoznoĭ infektsii.