title: [Is there a connection between intramedullary pressure increase, bone marrow intravasation and deep venous thrombosis of the leg in endoprosthetics?].
abstract: Deep vein thrombosis still is a severe problem in hip replacement. Based on pathophysiological considerations, it is postulated that there is a connection between intramedullary pressure peaks, resulting intravasation of bone marrow, and the induction of deep vein thrombosis. The content of the bone marrow cavity can be considered active where coagulation is concerned. Intravasation may contribute to the development of deep vein thrombosis. In addition to medicamentous prophylaxis and early mobilization, a surgical technique also helps in the prophylaxis thrombosis. In this technique, intramedullary pressure increases are avoided as far as possible, which consequently minimizes intravasation of the content of the bone marrow cavity.
authors.affiliation: Klinik für Unfallchirurgie, Universitätsklinikum Mainz.
authors.forename: K
authors.initials: K
authors.lastname: Wenda
authors.forename: K
authors.initials: K
authors.lastname: Lauer
authors.forename: S
authors.initials: S
authors.lastname: Boor
authors.forename: M
authors.initials: M
authors.lastname: Runkel
authors.forename: K F
authors.initials: KF
authors.lastname: Kreitner
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001178:Arthroplasty / Q000379:methods; D001777:Blood Coagulation; D001853:Bone Marrow / Q000503:physiopathology*; D006493:Heparin / Q000627:therapeutic use; D006622:Hip Prosthesis; D006801:Humans; D008875:Middle Aged; D010690:Phlebography; D011312:Pressure; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000517:prevention & control
chemical_list: D006493:Heparin
vernacular_title: Gibt es in der Endoprothetik einen Zusammenhang zwischen intramedullärer Druckerhöhung, Knochenmarkeinschwemmungen und tiefen Beinvenenthrombosen?