Carbazole alkaloid with antimicrobial activity from Clausena heptaphylla.
A new carbazole alkaloid designated as clausenal was isolated from the leaves of Clausena heptaphylla and its structure established as 1,8-dimethoxy-3-formylcarbazole from physical, chemical and synthetic evidence. The alkaloid was found to be active against both Gram-positive and Gram-negative bacteria, and fungi.
Chakraborty
A
A
Department of Chemistry, School of Tropical Medicine, Calcutta, India.
Saha
C
C
Podder
G
G
Chowdhury
B K
BK
Bhattacharyya
P
P
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002227:Carbazoles / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D018515:Plant Leaves
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002227:Carbazoles; C093425:clausenal