Hepatitis B reactivation following allogeneic bone marrow transplantation: case report and review of the literature.
A case of hepatitis B reactivation following allogeneic bone marrow transplantation for acute myelogenous leukemia is reported. The presence of hepatitis B surface antibody prior to transplantation indicated previous infection with hepatitis B. The presence of hepatitis B surface antigen was first detected 21 months after transplantation. Testing for hepatitis B reactivation was prompted by the development of acute hepatitis B in the patient's spouse. Screening for hepatitis B infection may be helpful when abnormal liver function tests develop after bone marrow transplantation.
Martin
B A
BA
Department of Medicine, University of Rochester School of Medicine.
Rowe
J M
JM
Kouides
P A
PA
DiPersio
J F
JF
D000208:Acute Disease; D000328:Adult; D016026:Bone Marrow Transplantation; D006509:Hepatitis B / Q000175:diagnosis* / Q000635:transmission; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D006801:Humans; D007951:Leukemia, Myeloid / Q000628:therapy; D008297:Male; D012008:Recurrence
D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens