epsilon-Aminocaproic acid-associated myopathy in a child.
OBJECTIVE
A 12-year-old girl developed severe autoimmune thrombocytopenia after a bone marrow transplant for acute lymphoblastic leukemia.


RESULTS
Although epsilon-aminocaproic acid helped to control her bleeding, it eventually caused a rare myopathy previously undescribed in a pediatric patient.


CONCLUSIONS
The myopathy resolved when the drug was discontinued and a different antifibrinolytic agent was used.
Winter
S S
SS
Division of Hematology-Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Chaffee
S
S
Kahler
S G
SG
Graham
M L
ML
D015119:Aminocaproic Acid / Q000009:adverse effects*; D016026:Bone Marrow Transplantation; D002648:Child; D005260:Female; D006801:Humans; D009135:Muscular Diseases / Q000139:chemically induced*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*; D012008:Recurrence
D015119:Aminocaproic Acid