The present and future of bradykinin antagonists.
It is now just a decade since the first evidence was obtained for bradykinin antagonists effective on most systems (B2 antagonists). During that decade antagonists have been used to elucidate roles for kinins in physiology and pathophysiology, and are now in clinical trials. Some of these developments, as well as prospects for future developments, are reviewed.
Stewart
J M
JM
Department of Biochemistry, University of Colorado School of Medicine, Denver 80262, USA.
D001920:Bradykinin / Q000037:antagonists & inhibitors*; D065168:Bradykinin Receptor Antagonists; D005544:Forecasting; D006801:Humans
D065168:Bradykinin Receptor Antagonists; D001920:Bradykinin