Home-cage ethanol consumption and motor activity: lack of relation to either initial activity or amphetamine-induced locomotion.
In two separate studies, the relationship between home-cage, two bottle ethanol/water consumption and both initial motor reactivity to a novel environment and amphetamine induced motor activity was determined in nonselected Wistar rats. In neither study was any correlation found. While home-cage ethanol consumption may not be an accurate measure of ethanol self-administration, the studies suggest that unlike reports for other drugs of abuse, there does not appear to be a simple relationship between alcohol preference and motor activity.
Samson
H H
HH
Department of Physiology and Pharmacology, Bowman Gray School of Medicine, Winston-Salem, NC 27157-1083, USA.
Chappelle
A M
AM
D000428:Alcohol Drinking / Q000523:psychology*; D000818:Animals; D003913:Dextroamphetamine / Q000494:pharmacology*; D004298:Dopamine / Q000502:physiology; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar
D003913:Dextroamphetamine; D004298:Dopamine