Preparation of organic solvent-tolerant mutants from Pseudomonas aeruginosa strain PAO1161.
Most organic solvents (OSs) are toxic and inhibit growth of microorganisms even at low concentrations. Therefore, they are used to sterilize microbial cultures and to maintain solutions in a sterile condition. However, the physiological basis of such phenomenon is poorly understood. Although there are some microorganisms that can utilize a number of OSs as their sole carbon and energy sources, OSs must be provided as a vapor or at a very low concentration to avoid growth inhibition.
Komatsu
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T
Deep Star Group, Japan Marine Science and Technology Center, Yokosuka, Japan.
Moriya
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Horikoshi
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K
D004361:Drug Tolerance; D006586:Hexanes / Q000633:toxicity*; D009154:Mutation; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000235:genetics*; D012997:Solvents; D014992:Xylenes / Q000633:toxicity*
D006586:Hexanes; D012997:Solvents; D014992:Xylenes; C026385:n-hexane; C031286:4-xylene