Differential expression of Xenopus BMPs in early embryos and tissues.
Expression levels of mRNA for Xenopus bone morphogenetic proteins (BMPs) in early embryos and adult organs were examined. Reverse transcription-polymerase chain reaction (RT-PCR) that used specific primers for each BMP subtype revealed that mRNAs for BMP-2 and BMP-4 are distributed in a wide variety of adult tissues including lung, heart, and kidney. Unexpectedly, distribution of mRNA for BMP-7 was found to be limited to ovary and early embryos. The result suggests that Xenopus BMP-7 may have a specific role in ovary and early embryos.
Suzuki
A
A
Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan.
Nishimatsu
S
S
Murakami
K
K
Ueno
N
N
D000818:Animals; D001483:Base Sequence; D019485:Bone Morphogenetic Proteins; D004625:Embryo, Nonmammalian / Q000378:metabolism; D005786:Gene Expression Regulation; D006133:Growth Substances / Q000096:biosynthesis* / Q000235:genetics; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D011506:Proteins / Q000235:genetics; D014982:Xenopus laevis / Q000196:embryology* / Q000235:genetics
D019485:Bone Morphogenetic Proteins; D006133:Growth Substances; D011506:Proteins