title: Congenital diaphragmatic hernia: survival treated with very delayed surgery, spontaneous respiration, and no chest tube.
abstract: This report suggests that stabilization of the intrauterine to extrauterine transitional circulation combined with a respiratory care strategy that avoids pulmonary overdistension, takes advantage of inherent biological cardiorespiratory mechanics, and very delayed surgery for congenital diaphragmatic hernia results in improved survival and decreases the need for extracorporeal membrane oxygenation (ECMO). This retrospective review of a 10-year experience in which the respiratory care strategy, ECMO availability, and technique of surgical repair remained essentially constant describes the evolution of this method of management of congenital diaphragmatic hernia.
authors.affiliation: Division of Pediatric Surgery, Columbia University, College of Physicians and Surgeons, New York, NY, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Wung
authors.forename: R
authors.initials: R
authors.lastname: Sahni
authors.forename: S T
authors.initials: ST
authors.lastname: Moffitt
authors.forename: E
authors.initials: E
authors.lastname: Lipsitz
authors.forename: C J
authors.initials: CJ
authors.lastname: Stolar
mesh_terms: D015505:Chest Tubes; D004630:Emergencies; D015199:Extracorporeal Membrane Oxygenation; D006548:Hernia, Diaphragmatic / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D012121:Respiration, Artificial; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome; D015300:Ventilator Weaning