[Stewart-Treves syndrome. Immunohistochemical study apropos of 2 cases].
Two women (63 and 68 years) presented with primary angiosarcomas of the skin which had developed on an area of chronic lymphoedema after radiosurgical treatment for breast cancer 4 and 13 years earlier. Immunohistochemistry tests formally eliminated epithelial metastasis and produced evidence in favour of lymphatic or capillary vascular proliferation. Endothelial affinity for anti-factor VIII and positive tests for certain markers of intermediary filaments (actin, vimentin) confirmed the vascular and conjunctive tissue origin of the tumours.
Le Bouëdec
G
G
Centre Jean Perrin, Clermont-Ferrand.
Buono
J P
JP
De Latour
M
M
Toledano
E
E
Vergote
T
T
Dauplat
J
J
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000601:surgery; D005260:Female; D006394:Hemangiosarcoma / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision / Q000009:adverse effects; D008209:Lymphedema / Q000209:etiology*; D015409:Mastectomy, Radical / Q000009:adverse effects*; D008875:Middle Aged; D011183:Postoperative Complications; D012878:Skin Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013577:Syndrome
Syndrome de Stewart-Treves. Etude immunohistochimique de 2 cas.