Paroxysmal nocturnal haemoglobinuria and Budd-Chiari syndrome.
An 11 year old boy developed pancytopenia, haemolysis, and Budd-Chiari syndrome. The venous thrombosis extended to involve other intra-abdominal vessels before paroxysmal nocturnal haemoglobinuria was recognised as the underlying haematological abnormality. Earlier diagnosis would have made curative bone marrow transplantation a possibility.
Wyatt
H A
HA
Department of Child Health, King's College Hospital, Denmark Hill, London.
Mowat
A P
AP
Layton
M
M
D016026:Bone Marrow Transplantation; D006502:Budd-Chiari Syndrome / Q000209:etiology*; D002648:Child; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications* / Q000628:therapy; D006801:Humans; D008297:Male