title: [Management of laryngeal cancers].
abstract: With 5,000 cases yearly, laryngeal carcinomas account in France for the third of squamous cell cancers of the upper digestive and respiratory tract. The crude survival rate is 50% at 5 years. Carcinomas of vocal cords are often diagnosed as early stages if dysphonia leads the patients to the ENT specialist within 2 weeks. Cure of the primary is achieved in 90% of the early stages by radiotherapy with narrow fields or partial surgery, with a 80% 5 years survival rate. Advanced tumors are often treated by total laryngectomy and postoperative radiotherapy. Supra-glottic cancers (epiglottis) are more serious. Unilateral dysphagia or upper cervical neck node often delay early diagnosis. A total laryngectomy is the commonest treatment. The 5 years survival rate of 40% is due to local and/or regional failures and metachronous cancers in head and neck, and radiotherapy remains the two major treatments. Primary prevention is based upon suppression of tobacco and reduction of alcoholic consumption, secondary prevention on resection of leucoplakia and close follow-up of patients with chronic laryngitis.
authors.affiliation: Service d'oncologie radiothérapique, Institut Curie, Paris.
authors.forename: F
authors.initials: F
authors.lastname: Brunin
authors.forename: J
authors.initials: J
authors.lastname: Rodriguez
authors.forename: S
authors.initials: S
authors.lastname: Cougniot-Lescure
authors.forename: D
authors.initials: D
authors.lastname: Point
authors.forename: C
authors.initials: C
authors.lastname: Jaulerry
authors.forename: J
authors.initials: J
authors.lastname: Brugère
mesh_terms: D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000534:rehabilitation / Q000628:therapy; D012307:Risk Factors
vernacular_title: Particularités des cancers du larynx.