Phase-contrast pulsatility measurements: preliminary results in normal and arteriosclerotic iliofemoral arteries. Work in progress.
Magnetic resonance (MR) flow measurements were obtained in six healthy volunteers and 30 patients with arteriosclerotic disease with a 1.5-T imager and a pulse sequence for flow quantification based on flow-induced phase shifts. The iliac arteries were investigated in eight and the femoral arteries in 28 subjects. A trigger pulse, followed by the acquisition of 30 evenly distributed data sets, was applied every second heartbeat, thus eliminating any acquisition gap in a full heart cycle. For quantitative analysis, flow velocity was plotted as a function of time. Systolic acceleration, postsystolic deceleration, and pulsatility of flow were calculated and compared with stenosis grades determined from recent intraarterial digital subtraction angiograms. The flattening of the temporal flow patterns correlated with local severity of vascular occlusive disease.
Krug
B
B
Department of Radiology, University of Cologne, Köln-Lindenthal, Germany.
Kugel
H
H
Harnischmacher
U
U
Heindel
W
W
Schmidt
R
R
Krings
F
F
D000328:Adult; D001161:Arteriosclerosis / Q000175:diagnosis* / Q000503:physiopathology; D001783:Blood Flow Velocity; D005263:Femoral Artery / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D007083:Iliac Artery / Q000502:physiology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged