Two antitumour bicyclic hexapeptides from Rubia cordifolia.
Two novel antitumour bicyclic hexapeptides, named RA-XV and -XVI, were isolated from Rubia cordifolia and their structures were characterized by spectroscopic and chemical means.
Takeya
K
K
Department of Pharmacognosy, Tokyo College of Pharmacy, Japan.
Yamamiya
T
T
Morita
H
H
Itokawa
H
H
D000595:Amino Acid Sequence; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010940:Plant Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D009842:Oligopeptides; D010456:Peptides, Cyclic; D010940:Plant Proteins