title: Endoscopic and Caldwell-Luc approaches in chronic maxillary sinusitis: a comparative histopathologic study on preoperative and postoperative mucosal morphology.
abstract: The aim of the present investigation was to study the histopathologic mucosal changes occurring in chronic maxillary sinusitis both preoperative and postoperative to functional endoscopic sinus (FES) surgery and the Caldwell-Luc (C-L) operation. Correlations were also sought between the histopathologic parameters and endoscopic findings, as well as patient symptoms. Sixty sinuses with the FES surgery and 55 sinuses with the C-L procedure were studied. The histologic parameters were graded semiquantitatively and compared preoperatively and postoperatively. The C-L operation reduced almost all parameters, whereas after the FES operation only edema and inflammatory cells were significantly reduced. Fibrosis increased postoperatively with both methods. The number of inflammatory cells was closely correlated to a thickened antral mucosa and to purulent secretion. No valid correlations were found when comparing histology with patient symptoms. All in all, histologic considerations suggest that asthmatic patients with severe sinonasal polyposis might benefit from the C-L procedure.
authors.affiliation: Department of Otorhinolaryngology, Huddinge University Hospital, Karolinska Institute, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Forsgren
authors.forename: M
authors.initials: M
authors.lastname: Fukami
authors.forename: M
authors.initials: M
authors.lastname: Penttilä
authors.forename: J
authors.initials: J
authors.lastname: Kumlien
authors.forename: P
authors.initials: P
authors.lastname: Stierna
mesh_terms: D001249:Asthma; D001706:Biopsy; D002908:Chronic Disease; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D015523:Maxillary Sinusitis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D009297:Nasal Mucosa / Q000473:pathology* / Q000648:ultrastructure