title: [MR imaging-evaluation of therapeutic effect of radiotherapy for uterine cervix cancer].
abstract: The purpose of this study was to assess the diagnostic efficacy of MR imaging in evaluating the therapeutic effect of radiotherapy for carcinoma of the uterine cervix. Twenty patients with advanced carcinoma of the cervix who underwent radiotherapy were examined. Based on the comparison between tumor size on the T2-weighted image before and after treatment, the response rate was as follows: CR 11, PR8 and NC 1. The response rate of the cases with a maximum tumor size less than 5 cm on MR images was superior to that of those with one larger than 6 cm. There was no correlation between clinical stage (FIGO) and response rate. To evaluate accurately whether or not there was residual tumor at the end of treatment, we assessed the clinical findings in regard to recurrent tumor during 6 months after treatment that was used as the standard of reference. The findings of MR imaging and biopsy at the end of treatment were compared with the clinical findings. The accuracy of MR imaging was 90% (18/20) and that of biopsy was 80% (16/20). The accuracy in 14 cases that showed diagnostic accordance between MR imaging and histological findings of biopsy was 100% (14/14). Therefore, it was concluded that MR imaging is very useful to elevate diagnostic accuracy for evaluation of the therapeutic effect of cervical carcinoma.
authors.affiliation: Department of Radiology, Kobe University, School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Kitagaki
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy*