[Development and characterization of an absorbable temporary wound dressing].
Most of the temporary dressings used in the treatment of burns do not meet the objectives of a skin substitute concerning application, safety and comfort. Removal is often painful and traumatic and increases the risk of infection. Biodegradable polymers of lactic and caproic acid were developed as part of a research programme (BMFT/FRG 01 KG 8809/7), and chemical and physical properties were investigated. Films made of the copolymer material were characterized by structure, transparency, permeability, tensile strength, flexibility and degradation. The transparent films appeared increasingly opaque during hydrolysis. The water vapour permeance could be varied between 40 and 250 (40-136) ml/m2 per h (according to the method of measurement). The mechanical properties are characterized by a maximum elongation of > 2000% at 37 degrees C and a very low elastically modulus. When the results were compared with those of three established film dressings, no restriction was found in the aptitude of the material as a wound dressing.
Jürgens
C
C
Abteilung für Unfall- und Wiederherstellungschirurgie, Berufsgenossenschaftliches Unfallkrankenhaus Hamburg.
Porte
T
T
Wolter
D
D
Schmidt
H G
HG
Kricheldorf
H R
HR
Kreiser-Saunders
I
I
D000818:Animals; D001458:Bandages; D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D002056:Burns / Q000628:therapy*; D006801:Humans; D007773:Lactates / Q000737:chemistry; D019344:Lactic Acid; D008855:Microscopy, Electron, Scanning; D008859:Microscopy, Polarization; D011091:Polyesters / Q000737:chemistry; D011108:Polymers / Q000737:chemistry
D001672:Biocompatible Materials; D007773:Lactates; D011091:Polyesters; D011108:Polymers; C016240:polycaprolactone; D019344:Lactic Acid; C033616:poly(lactide)
Entwicklung und charakterisierung einer absorbierbaren temporären Wundabdeckung.