Infrequent detection of Chlamydia trachomatis in a longitudinal study of women with treated cervical infection.
OBJECTIVE
To determine how often Chlamydia trachomatis cervical infections are detected in women following completion of a currently recommended treatment regimen and the reason for recurrence.


METHODS
A longitudinal follow-up study of 43 initially C trachomatis-positive women for periods of up to two years.


RESULTS
C trachomatis was detected in three women, 19, 16 and about four months, respectively after completion of treatment. All specimens from the other 40 women which were taken during visits two to seven, that is periods of three to 700 days after treatment, were chlamydia-negative.


CONCLUSIONS
Although C trachomatis is usually eradicated from the genital tract by conventional treatment, occasionally it may be found again. It is difficult to determine whether detection after treatment is due to persistence or reinfection and further studies are required.
Munday
P E
PE
Department of Genitourinary Medicine, Watford General Hospital, Herts, UK.
Thomas
B J
BJ
Gilroy
C B
CB
Gilchrist
C
C
Taylor-Robinson
D
D
D000328:Adult; D002584:Cervix Uteri / Q000821:virology; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D005260:Female; D005455:Fluorescent Antibody Technique; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D016133:Polymerase Chain Reaction; D012008:Recurrence; D002577:Uterine Cervical Diseases / Q000175:diagnosis / Q000821:virology*