Stereoselective synthesis of regioisomers of aldobiouronic acid.
alpha-Glucuronidase is a very important enzyme for the complete hydrolysis of plant hemicellulose, but the substrate specificity of the enzyme has not previously been reported. In this connection, the three regioisomers of O-(alpha-D-glucopyranosyluronic acid)-D-xylose (aldobiouronic acid), 2-O-(alpha-D-glucopyranosyluronic acid)-D-xylose (13), 3-O-(alpha-D-glucopyranosyluronic acid)-D-xylose (14), and 4-O-(alpha-D-glucopyranosyluronic acid)-D-xylose (15), were stereoselectively synthesized to clarify the substrate specificity.
Kawabata
Y
Y
Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan.
Gama
Y
Y
Kusakabe
I
I
D002240:Carbohydrate Sequence; D004187:Disaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D006031:Glycosylation; D008969:Molecular Sequence Data; D013237:Stereoisomerism; D013400:Sugar Acids / Q000138:chemical synthesis* / Q000737:chemistry
C089477:3-O-(glucopyranosyluronic acid)xylose; D004187:Disaccharides; D013400:Sugar Acids; C089476:2-O-(glucopyranosyluronic acid)xylose; C089480:4-O-(glucopyranosyluronic acid)xylose