title: Is laparoscopy associated with a lower rate of postoperative adhesions than laparotomy? A comparative study in the rabbit.
abstract: This trial set out to test the hypothesis that there is no difference in the incidence of intra-abdominal adhesions after a stereotyped intraperitoneal injury created via laparoscopy or laparotomy. Twenty New Zealand White rabbits had a 2 x 2 cm area of peritoneum stripped off their caecum and adjacent parietal peritoneum, either by laparotomy or laparoscopy. Outcome was assessed by the incidence of adhesions to the test site and the wound. There was no difference in the rate of adhesions at the test site in the two groups. The rate of adhesions to the wound was different in the two groups (70% laparotomy, 0% laparoscopy; P = 0.003). In a rabbit model, comparing laparoscopy and laparotomy in a strictly controlled operative environment, a stereotyped intraperitoneal injury results in similar rates of postoperative adhesions. Laparoscopy is, however, associated with a much lower incidence of wound adhesion. The potential for postoperative adhesions is real after laparoscopic surgery.
authors.affiliation: Laparoscopic Research Unit, St George Hospital, Sydney, New South Wales, Australia.
authors.forename: J O
authors.initials: JO
authors.lastname: Jorgensen
authors.forename: N J
authors.initials: NJ
authors.lastname: Lalak
authors.forename: D R
authors.initials: DR
authors.lastname: Hunt
mesh_terms: D000818:Animals; D015994:Incidence; D007410:Intestinal Diseases / Q000453:epidemiology / Q000209:etiology*; D010535:Laparoscopy / Q000009:adverse effects*; D007813:Laparotomy / Q000009:adverse effects*; D010537:Peritoneum / Q000293:injuries; D011183:Postoperative Complications; D011817:Rabbits; D011897:Random Allocation; D000267:Tissue Adhesions / Q000453:epidemiology / Q000209:etiology