A combined immunocytochemical and retrograde tracing study of noradrenergic connections between the caudal medulla and bed nuclei of the stria terminalis.
Region-specific noradrenergic inputs to the bed nuclei of the stria terminalis (BST) from the caudal medulla were studied using combined Fast Blue injections and tyrosine hydroxylase immunoreactivity (TH-ir). Injections into the rostral, dorsal, ventral and lateral BST resulted in predominantly ipsilateral retrograde labelling restricted to the mediodorsal and ventrolateral caudal medulla. Mediodorsal projecting neurones comprised the A2 TH-ir and a second non-aminergic group medial to A2. All ventrolateral retrogradely labelled neurons showed TH-ir and corresponded to A1. Injections into the caudal BST did not label the A2 and very few A1 neurones, indicating a paucity of noradrenergic inputs from this area of the medulla.
Terenzi
M G
MG
Department of Anatomy, University of Bristol, UK.
Ingram
C D
CD
D000578:Amidines; D000818:Animals; D005260:Female; D005456:Fluorescent Dyes; D007150:Immunohistochemistry; D008526:Medulla Oblongata / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D009638:Norepinephrine / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013788:Thalamus / Q000502:physiology*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
D000578:Amidines; D005456:Fluorescent Dyes; C031455:diamidino compound 253-50; D014446:Tyrosine 3-Monooxygenase; D009638:Norepinephrine