title: Intracellular transduction in the regulation of pheromone biosynthesis of the silkworm, Bombyx mori: suggested involvement of calmodulin and phosphoprotein phosphatase.
abstract: We have tested the effects of chemicals on bombykol production in vitro in the silkworm, Bombyx mori, to probe the biochemical steps as well as underlying mechanisms regulated by PBAN. These results suggest the involvement of calmodulin and phosphoprotein phosphatase in the intracellular signal transduction of PBAN action.
authors.affiliation: Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Matsumoto
authors.forename: R
authors.initials: R
authors.lastname: Ozawa
authors.forename: T
authors.initials: T
authors.lastname: Nagamine
authors.forename: G H
authors.initials: GH
authors.lastname: Kim
authors.forename: K
authors.initials: K
authors.lastname: Uchiumi
authors.forename: T
authors.initials: T
authors.lastname: Shono
authors.forename: T
authors.initials: T
authors.lastname: Mitsui
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D012831:Bombyx / Q000378:metabolism*; D002147:Calmodulin / Q000378:metabolism*; D005233:Fatty Alcohols / Q000378:metabolism*; D005260:Female; D008969:Molecular Sequence Data; D010675:Pheromones / Q000096:biosynthesis*; D010749:Phosphoprotein Phosphatases / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology*; D014268:Trifluoperazine / Q000494:pharmacology
chemical_list: D002147:Calmodulin; D005233:Fatty Alcohols; D010675:Pheromones; D014268:Trifluoperazine; C006787:bombykol; D010749:Phosphoprotein Phosphatases