title: [Large nodular, multicenter, juvenile xanthogranuloma with ulceration].
abstract: We report on a patient with multicentric juvenile xanthogranuloma, whose unusual clinical and histological pattern initially obscured the diagnosis. Spontaneous remission of the tumour, which has now been maintained for over 2 years, the change from the primary monomorphological fibrocytic appearance to a polymorphological histiocytic picture with multiple fat-storing giant cells, and the lacking dermonstration of specific cell organelles finally allowed the nature of the disease to the definitely diagnosed.
authors.affiliation: Dermatologische Klinik, Ruhr-Universität Bochum.
authors.forename: P
authors.initials: P
authors.lastname: Altmeyer
authors.forename: T
authors.initials: T
authors.lastname: Kemper
authors.forename: R
authors.initials: R
authors.lastname: Hartwig
authors.forename: M
authors.initials: M
authors.lastname: Bacharach-Buhles
authors.forename: K
authors.initials: K
authors.lastname: Donhuijsen
mesh_terms: D003937:Diagnosis, Differential; D005455:Fluorescent Antibody Technique; D006229:Hand Dermatoses / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000473:pathology; D012883:Skin Ulcer / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology; D013933:Thumb / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000151:congenital* / Q000175:diagnosis* / Q000473:pathology
vernacular_title: Grossknotiges, multizentrisches, juveniles Xanthogranulom mit Ulzeration.