title: [The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome].
abstract: The drug encorat, an analogue of valproic acid (Sun, India) was given to 16 children aged from 4 month to 5 years suffering from resistant forms of early infantile epilepsy. Twelve of them had infantile spasms, four Lennox-Gastaut syndrome. The treatment produced good results in 75% of the patients. Encorat mono- or polychemotherapy is able to discontinue or decrease the frequency of the epileptic fits, improve the patients' condition in resistant early childhood epilepsy.
authors.forename: L O
authors.initials: LO
authors.lastname: Badalian
authors.forename: P A
authors.initials: PA
authors.lastname: Temin
authors.forename: M I
authors.initials: MI
authors.lastname: Medvedev
authors.forename: K Iu
authors.initials: KIu
authors.lastname: Mukhin
authors.forename: M B
authors.initials: MB
authors.lastname: Iskander
authors.forename: D A
authors.initials: DA
authors.lastname: Kharlamov
authors.forename: N K
authors.initials: NK
authors.lastname: Veselov
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D002220:Carbamazepine / Q000627:therapeutic use; D002675:Child, Preschool; D002998:Clonazepam / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000175:diagnosis / Q000188:drug therapy*; D005013:Ethosuximide / Q000627:therapeutic use; D005260:Female; D006429:Hemiplegia / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D012074:Remission Induction; D013036:Spasms, Infantile / Q000175:diagnosis / Q000188:drug therapy*; D013577:Syndrome; D013997:Time Factors; D014635:Valproic Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*
chemical_list: D000927:Anticonvulsants; C093456:encorat; D002220:Carbamazepine; D002998:Clonazepam; D005013:Ethosuximide; D014635:Valproic Acid
vernacular_title: Lechenie énkoratom infantil'nykh spazmov i sindroma Lennoksa--Gasto.