Anaplastic renal cell carcinoma following neuroblastoma.
Renal cell carcinoma is unusual in children. We report a case of anaplastic renal cell carcinoma arising in a 7-year-old girl following treatment for Stage III neuroblastoma. The renal cell carcinoma has unusual histologic and ultrastructural features, which are discussed. The case is further unusual in that few children with advanced stage neuroblastoma survive long enough to develop second malignant neoplasms.
Krigman
H R
HR
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Bentley
R C
RC
Strickland
D K
DK
Miller
C R
CR
Dehner
L P
LP
Washington
K
K
D000708:Anaplasia; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000648:ultrastructure; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007680:Kidney Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D016609:Neoplasms, Second Primary / Q000473:pathology*; D009447:Neuroblastoma / Q000628:therapy*