Biotransformation of alpha- and beta-ionones by immobilized cells of Nicotiana tabacum.
Immobilized cells of Nicotiana tabacum reduced the carbon-carbon double bond adjacent to the carbonyl group and then the carbonyl group itself of the dienone compounds, alpha-ionone and beta-ionone. In addition, the selectivity for the reduction of the double bond adjacent to the carbonyl group could be enhanced by performing the biotransformation in medium with a pH near the optimal pH of the enone reductase which specifically catalyses the reduction of the alpha, beta-unsaturated double bond of s-trans-enones.
Tang
Y X
YX
Department of Chemistry, Faculty of Science, Hiroshima University, Japan.
Suga
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D001711:Biotransformation; D002384:Catalysis; D002478:Cells, Cultured; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D045792:Norisoprenoids; D010084:Oxidation-Reduction; D010947:Plants, Toxic; D013729:Terpenes / Q000378:metabolism* / Q000493:pharmacokinetics; D014026:Nicotiana / Q000378:metabolism*
D045792:Norisoprenoids; D013729:Terpenes; C008157:beta-ionone; C011879:alpha-ionone