Medulloblastoma in pediatric age: a single-institution review of prognostic factors.
We report a retrospective study of 35 cases of medulloblastoma in pediatric patients treated at our institution during an 18-year period. Ten of the patients were infants (age < 2 years) and 25 were children (age > 2 years). The main factors affecting prognosis were total removal of the tumor (P < 0.01) and tumor stage (P < 0.01). There were no differences between the survival rate of infants and children, infants had a worse prognosis in regard to quality of life than children.
Cervoni
L
L
Department of Neurological Sciences, La Sapienza University of Rome, Italy.
Cantore
G
G
D000293:Adolescent; D001925:Brain Damage, Chronic / Q000209:etiology / Q000401:mortality; D002528:Cerebellar Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007360:Intelligence / Q000502:physiology; D008297:Male; D008527:Medulloblastoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D011788:Quality of Life; D012189:Retrospective Studies; D015996:Survival Rate