title: Photomedicine of the endometrium: experimental concepts.
abstract: Gynaecological photomedicine offers new diagnostic and therapeutic methods based on the interaction of light with the reproductive organs. One example is photodynamic therapy (PDT) in which photosensitizers are applied systemically or topically for selective endometrial ablation. Several studies describing the potential use of PDT for this application are reviewed. Basic experimental and clinical aspects of PDT, such as photosensitizer types, application modes, irradiation parameters, optical properties of tissues and photodegradation of photosensitizers are discussed.
authors.affiliation: Beckman Laser Institute and Medical Clinic, University of California, Irvine 92715, USA.
authors.forename: P
authors.initials: P
authors.lastname: Wyss
authors.forename: L O
authors.initials: LO
authors.lastname: Svaasand
authors.forename: Y
authors.initials: Y
authors.lastname: Tadir
authors.forename: U
authors.initials: U
authors.lastname: Haller
authors.forename: M W
authors.initials: MW
authors.lastname: Berns
authors.forename: M T
authors.initials: MT
authors.lastname: Wyss
authors.forename: B J
authors.initials: BJ
authors.lastname: Tromberg
mesh_terms: D000818:Animals; D004717:Endometrium / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D005260:Female; D006801:Humans; D008027:Light; D055095:Optics and Photonics; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000493:pharmacokinetics; D012099:Reproductive Techniques
chemical_list: D017319:Photosensitizing Agents