Effects of a modified-live virus canine distemper vaccine on captive badgers (Taxidea taxus).
We vaccinated six captive badgers housed with five controls, and monitored blood antibody titers and white cell counts of both groups for 63 days postvaccination between 29 August and 3 December 1992. Five vaccinated badgers responded with antibody titers ranging from 1:64 to 1:1024 by 63 days postvaccination, whereas the sixth badger did not respond. Treatment badgers also had significant (P < 0.05) decreases in lymphocytes on days 16, 29, and 63. No badgers developed clinical signs of distemper. Control badgers did not produce antibodies against CD virus; thus, the vaccine virus probably was not transmitted between treatment and control animals. The vaccine appears safe for use in healthy badgers, but additional safety and efficacy study is needed.
Goodrich
J M
JM
Department of Zoology and Physiology University of Wyoming, Laramie 82071.
Williams
E S
ES
Buskirk
S W
SW
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002335:Carnivora; D004216:Distemper / Q000517:prevention & control*; D004217:Distemper Virus, Canine / Q000276:immunology*; D005260:Female; D008297:Male; D009500:Neutralization Tests / Q000662:veterinary; D014611:Vaccination / Q000662:veterinary; D014765:Viral Vaccines / Q000276:immunology
D000914:Antibodies, Viral; D014765:Viral Vaccines