title: Role of routine lumbar puncture in neonatal sepsis.
abstract: OBJECTIVE
  To evaluate the utility of lumbar puncture done routinely as part of complete workup in neonatal sepsis.
  
  
  METHODS
  Two hundred and nine consecutive lumbar punctures performed in 169 neonates were prospectively evaluated for the diagnosis of meningitis over a 6 month period in a tertiary care referral neonatal unit.
  
  
  RESULTS
  Among babies with 'suspected clinical sepsis', five (3.3%) were diagnosed to have meningitis. None of the clinically normal babies with high risk obstetric factors alone had meningitis. The lumbar puncture was traumatic in 22.9%, and in 26.3% the fluid obtained was inadequate for complete analysis. The results were inconclusive in 37% of the cases.
  
  
  CONCLUSIONS
  Based on this study, routine lumbar puncture may not be required in clinically normal newborns with adverse obstetric factors. In babies with clinical sepsis, though the yield is not very high; there are no reliable clinical or laboratory markers to predict which babies will have meningitis and hence these babies would warrant a lumbar puncture.
authors.affiliation: Department of Pediatrics, PGIMER, Chandigarh, India.
authors.forename: P
authors.initials: P
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Sarkar
authors.forename: A
authors.initials: A
authors.lastname: Narang
mesh_terms: D001724:Birth Weight; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008581:Meningitis / Q000175:diagnosis*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D011446:Prospective Studies; D012307:Risk Factors; D018805:Sepsis / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D013129:Spinal Puncture / Q000009:adverse effects