[Evaluation of the redox tolerance index on hepatic energy charge of hepatitis B patients].
To evaluate hepatic energy charge, we detected the redox tolerance index (RTI) in 27 patients with chronic hepatitis B (CH) and 34 patients with post-hepatitis B liver cirrhosis (LC). The results demonstrated that RTI was significantly lower in CH and LC than that in the normal controls (P < 0.01). There was no difference between CH and LC. The active LC showed RTI significantly lower than that of the inactive LC (P < 0.05). The results also indicated that there was no correlation between the RTI and routine liver function. Our findings suggest that RTI based on redox theory is of value in predicting hepatic energy charge accurately.
Liu
Z J
ZJ
Department of Medicine, Second Affiliated Hospital, Henan University, Zhengzhou.
Xu
Z L
ZL
D000328:Adult; D000368:Aged; D004734:Energy Metabolism; D006509:Hepatitis B / Q000150:complications / Q000378:metabolism*; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology / Q000378:metabolism; D008875:Middle Aged; D008930:Mitochondria, Liver / Q000378:metabolism*; D010084:Oxidation-Reduction