title: Evaluation of large-needle biopsy for the diagnosis of cancer.
abstract: The arguments for a choice between a large or fine needle in the diagnosis of tumors are still unclear. This paper reviews the advantages and disadvantages of large-needle biopsy and fine needle aspiration. Reports indicate that although the procedures have the same diagnostic efficacy, the risk of tumor seeding is far higher following large-needle biopsy. For this reason it should be avoided for the diagnosis of cancer. The risk of tumor seeding after fine needle aspiration may be reduced by performance through a cover of normal parenchyma, by maintaining suction during withdrawal of the needle and by examining samples for quality during the procedure.
authors.affiliation: Laboratoire d'Histologie, Centre Hospitalier et Universitaire de Rouen, Hôpital Charles Nicolle, France.
authors.forename: F
authors.initials: F
authors.lastname: Roussel
authors.forename: G
authors.initials: G
authors.lastname: Nouvet
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis; D001707:Biopsy, Needle / Q000009:adverse effects / Q000379:methods*; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis; D005069:Evaluation Studies as Topic; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis; D009366:Neoplasm Seeding; D009369:Neoplasms / Q000175:diagnosis*; D010997:Pleural Neoplasms / Q000175:diagnosis; D011471:Prostatic Neoplasms / Q000175:diagnosis; D012307:Risk Factors