title: [Alteration of the taste for sugar in renal insufficiency: study in the child].
abstract: Children with chronic renal failure (CRF) show a reduced appetite for sweet foods. Sensory responses to sweet stimuli were investigated in 45 children with CRF, 39 dialyzed patients (HD) and 25 controls(C). Two familiar foods were prepared in 5 sucrose concentrations: 1, 5, 10, 15, 20% for soft white cheese (SWC): 10, 20, 30, 40, 60% for apple sauce (AS). When identifying the sweeter of two SWC samples, CRF(15%) and HD (18%) made more mistakes than C (5%). When testing AS, mistakes were comparable between groups (25, 21, 19%). Preferences differed according to diagnosis group. The sweetest SWC was preferred by 40% of CRF and C and by only 22% HD; the least sweet SWC was preferred by 5% of C, 10% of CRF and 16% of HD. In AS, the highest concentrations were preferred by CRF and C, median concentration by HD. Plasma zinc had no clear effect on taste. Altered preferences for sweet foods in patients suggest post-ingestive adverse effects of sucrose resulting from an altered sucrose metabolism.
authors.affiliation: INSERM U341, Hôtel-Dieu, Paris.
authors.forename: F
authors.initials: F
authors.lastname: Bellisle
authors.forename: A M
authors.initials: AM
authors.lastname: Dartois
authors.forename: C
authors.initials: C
authors.lastname: Kleinknecht
authors.forename: M
authors.initials: M
authors.lastname: Broyer
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005518:Food Preferences; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology*; D008297:Male; D006435:Renal Dialysis; D013395:Sucrose; D013649:Taste; D015032:Zinc / Q000097:blood
chemical_list: D013395:Sucrose; D015032:Zinc
vernacular_title: Altération du goût pour le sucre dans l'insuffisance rénale: étude chez l'enfant.