title: [Treatment results of conformation radiotherapy for stage I and II cervical cancer].
abstract: From 1977 to 1989, 214 patients with stage I and II cervical cancer were treated with two-axial conformational irradiation to the whole pelvis and Ra-intracavitary irradiation at the Department of Radiotherapy, Aichi Cancer Center Hospital. We evaluated the treatment results in comparison with the results of patients treated by conventional methods in our affiliated hospitals. Furthermore, we analyzed the factors that influenced primary and distant failures. The total dose for the whole pelvis was 4000-4560 cGy/5 weeks, and the brachytherapy dose was 2000-2800 cGy at point A. The cumulative 5-year survival, recurrence-free survival and regional control rates were 82.8%, 91.7% and 93.0% for stage I B, and 70.7%, 79.9% and 90.7% for stage II. These results were almost the same as those of the conventional group. Grade 3 recto-sigmoidal complications were observed in three of 94 patients in the conventional group and none of 214 in the conformational group. This difference was statistically significant. From these results, we conclude that two-axial conformational whole-pelvis irradiation is useful for the reduction of late complications.
authors.affiliation: Department of Radiotherapy, Aichi Cancer Center.
authors.forename: E
authors.initials: E
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Morita
mesh_terms: D000368:Aged; D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*