[A case of primary orbital lymphoma with macroglobulinemia].
A rare case of primary orbital lymphoma with macroglobulinemia was reported. The patient was a 74-year-old male with bilateral orbital tumor. Exophthalmos and eye movement disturbance appeared in his left eye. Blood analysis showed a marked increase of serum immunoglobulin M. Immunochemical study showed 7,097 (mg/dl). The left tumor was partially removed and examined histopathologically and immunohistochemically. H.E. staining revealed the proliferation of lymphoplasmacytoid cells. Immunocytochemical staining showed these cells to be immunoglobulin G (-), immunoglobulin A (-), immunoglobulin M (+), immunoglobulin light chi-chain (-), immunoglobulin light lambda-chain (+), LCA (+), L-26(PAN-B)(+), MT-1(-), and UCHL(-). Based on these results, our diagnosis was non-Hodgkin's lymphoma of the diffuse small, lymphoplasmacytoid type.
Idei
N
N
Department of Ophthalmology, Kobe West City Hospital, Japan.
Hoshida
Y
Y
Ohshima
K
K
Mori
S
S
Fujimoto
S
S
Matsuo
N
N
D000368:Aged; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D008297:Male; D009918:Orbital Neoplasms / Q000150:complications*; D008258:Waldenstrom Macroglobulinemia / Q000209:etiology*