title: Nuclear DNA polymorphism in a Mandenka population from Senegal: comparison with eight other human populations.
abstract: A large and ethnically well defined Mandenka sample from Senegal is analysed for 80 nuclear DNA RFLPs, and compared with eight previously studied human populations. A high level of genetic diversity is found in this sample, comparable to that observed in two African Pygmy samples, but lower than that of a European sample. High population variation is observed for most markers. A neutrality test reveals that the markers used in this study can be considered as neutral. A high correlation is found between genetic and geographic distances (r = 0.62), suggesting that geography does also affect long range population genetic relationships and is an important factor behind differentiation among human populations.
authors.affiliation: Département d'Anthropologie et d'Ecologie, Université de Genève, Switzerland.
authors.forename: E S
authors.initials: ES
authors.lastname: Poloni
authors.forename: L
authors.initials: L
authors.lastname: Excoffier
authors.forename: J L
authors.initials: JL
authors.lastname: Mountain
authors.forename: A
authors.initials: A
authors.lastname: Langaney
authors.forename: L L
authors.initials: LL
authors.lastname: Cavalli-Sforza
mesh_terms: D000483:Alleles; D002467:Cell Nucleus / Q000737:chemistry; D004247:DNA / Q000235:genetics; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005819:Genetic Markers; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length; D044469:Racial Groups / Q000235:genetics; D012675:Senegal
chemical_list: D005819:Genetic Markers; D004247:DNA