Cytotoxic metabolites from a fungal adherent of a marine alga.
Leptosins G, G1, G2 and H, belonging to a series of dimeric epipolythiodioxopiperazines, were isolated from the mycelium of a strain of Leptosphaeria sp. stuck on the marine alga Sargassum tortile. Their stereostructures were elucidated by chemical and spectral evidence.
Takahashi
C
C
Osaka University of Pharmaceutical Sciences, Japan.
Takai
Y
Y
Kimura
Y
Y
Numata
A
A
Shigematsu
N
N
Tanaka
H
H
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification; D056890:Eukaryota / Q000382:microbiology*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010879:Piperazines / Q000737:chemistry* / Q000302:isolation & purification; D012623:Seawater; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013053:Spectrophotometry; D013098:Xylariales / Q000737:chemistry*
D000970:Antineoplastic Agents; D007202:Indicators and Reagents; D010879:Piperazines