[Morphologic changes following experimental influenza virus infection and the therapeutic administration of flavonoids in aqueous extract].
Influenza virus strain A/PR8/34(H1N1) and flavonoid aqueous extract with therapeutical function were administered by intranasal route. Pathological examinations were done three and ten days after administration to evaluate the morphological modifications established in the lung parenchyma. Results showed that therapeutical administration of flavonoids had good effects on interstitial bronchopneumonia evolution till complete recovery. Flavonoid aqueous extract administered by intranasal route was well tolerated by the organism.
Petica
M
M
Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.
Crişan
I
I
Eşanu
V
V
Petrescu
A
A
D000818:Animals; D005419:Flavonoids / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000473:pathology*; D012996:Solutions
D005419:Flavonoids; D012996:Solutions
Modifications morphologiques consécutives à l'infection expérimentale à virus de la grippe et à l'administration thérapeutique de flavonoïdes en extrait aqueux.