Clinical aspects of cardiovascular effects of H2-receptor antagonists.
In vitro studies and animal experiments as well as clinical observations in humans concerning cardiovascular effects of H2-receptor antagonists have been published shortly after the development. Thus, clinical studies were performed to investigate these effects. The following review summarizes the results from in vitro studies up to the clinical investigations performed.
Hinrichsen
H
H
Medical Department, Christian-Albrechts-University, Kiel, Germany.
Halabi
A
A
Kirch
W
W
D000818:Animals; D001283:Atrioventricular Node / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D001919:Bradycardia / Q000139:chemically induced; D002319:Cardiovascular System / Q000187:drug effects*; D002927:Cimetidine / Q000009:adverse effects / Q000494:pharmacology; D004562:Electrocardiography / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006635:Histamine H2 Antagonists / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D011899:Ranitidine / Q000009:adverse effects / Q000494:pharmacology
D006635:Histamine H2 Antagonists; D002927:Cimetidine; D011899:Ranitidine