Immunohistochemical characterisation of probable intravascular haematopoiesis in the vasa rectae of the renal medulla in acute tubular necrosis.
Immunohistochemistry was applied to identify the nature of the nucleated cells that accumulate in the vasa rectae of the corticomedullary junction in acute tubular necrosis. In all 6 cases studied, there were intravascular cells that reacted with monoclonal antibodies to erythroblast, macrophages, myeloid cells, T and B lymphocytes and rare megakaryocytes. The findings are consistent with the occurrence of intravascular haematopoiesis in the renal medulla in acute tubular necrosis.
Bacchi
C E
CE
Department of Pathology, School of Medicine, UNESP, Brazil.
Rocha
N
N
Carvalho
M
M
Schmitt
D
D
Schmitt
F
F
Franco
M
M
D000328:Adult; D000368:Aged; D001160:Arterioles / Q000473:pathology; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D007124:Immunoenzyme Techniques; D007679:Kidney Medulla / Q000098:blood supply* / Q000473:pathology; D007683:Kidney Tubular Necrosis, Acute / Q000473:pathology* / Q000503:physiopathology*; D008875:Middle Aged