Cardioactive steroid saponins and other constituents from the aerial parts of Tribulus cistoides.
From the petrol extract of the aerial parts of Tribulus cistoides three steroid sapogenins and two N-acyltyramines were isolated, whereas the methanolic extract gave nine steroid saponins, among them the cardioactive cistocardin, saponin-3, saponin-4 and saponin-7. Furthermore, a furostanol diglycoside was isolated besides 5'-(hydroxysulphonyloxy) jasmonic acid, D-(+)-pinitol and sucrose. The structures were established by spectroscopic investigations of the isolated compounds and their hydrolysis products. 5'-(Hydroxysulphonyloxy) jasmonic acid has been prepared by partial synthesis.
Achenbach
H
H
Department of Pharmaceutical Chemistry, University of Erlangen, Germany.
Hübner
H
H
Brandt
W
W
Reiter
M
M
D000818:Animals; D002240:Carbohydrate Sequence; D002317:Cardiovascular Agents / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008515:Medicine, Ayurvedic; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009132:Muscles / Q000187:drug effects; D010840:Phytosterols / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*
D002317:Cardiovascular Agents; D010840:Phytosterols; D012503:Saponins