title: Lumbosacral skin markers and identification of occult spinal dysraphism in neonates.
abstract: Some skin lesions over the spine are known to be associated with occult spinal dysraphism, but the significance of common skin lesions, such as sacral pits and dimples, is uncertain. In this prospective study, 95 neonates (1.9% of 4989 live births) were referred with possible markers of occult spinal dysraphism. Seven of 94 babies examined had abnormalities demonstrated by spinal ultrasound, compared with 5 of 105 controls. In 2 of 94 and 3 of 105 of these, the conus medullaris was located at L3 but no other abnormalities were found. Of the 75 babies with a sacral dimple or pit alone, none had an abnormality, suggesting that these skin lesions do not indicate a high risk of occult spinal dysraphism.
authors.affiliation: Department of Child Health, St. George's Hospital Medical School, London, UK.
authors.forename: P J
authors.initials: PJ
authors.lastname: Gibson
authors.forename: J
authors.initials: J
authors.lastname: Britton
authors.forename: D M
authors.initials: DM
authors.lastname: Hall
authors.forename: C R
authors.initials: CR
authors.lastname: Hill
mesh_terms: D015415:Biomarkers; D016022:Case-Control Studies; D006801:Humans; D007231:Infant, Newborn; D008161:Lumbosacral Region; D011446:Prospective Studies; D012307:Risk Factors; D012867:Skin / Q000473:pathology*; D016136:Spina Bifida Occulta / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D015415:Biomarkers