Antimicrobial sesquiterpenes from Prostanthera aff. melissifolia and P. rotundifolia.
Aerial material of Prostanthera aff. melissifolia and P. rotundifolia yielded three sesquiterpenes, two known compounds and a novel sesquiterpene, prostantherol. Prostantherol was identified as (rel)-1a alpha,3a beta,7a alpha,7b alpha-decahydro-4 beta-hydroxy- 1,1,4 alpha,7 alpha-tetramethylcyclopropa[a]-naphthalene on the basis of a comprehensive spectroscopic analysis. All three compounds were investigated for antimicrobial activity against phytopathogens.
Dellar
J E
JE
Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, U.K.
Cole
M D
MD
Gray
A I
AI
Gibbons
S
S
Waterman
P G
PG
D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010944:Plants / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000890:Anti-Infective Agents; D000935:Antifungal Agents; D012717:Sesquiterpenes