title: Gastric adenocarcinoma in a cougar (Felis concolor).
abstract: Diffusely invasive tumors occurred in the stomach of a 9-year-old female cougar (Felis concolor) from a zoo in Japan. The tumors consisted of tubular adenocarcinoma cells, and had infiltrative growth to the submucosa and muscularis propria. Tumor cells were positive for carcinoembryonic antigen (CEA), lysozyme, epithelial membrane antigen (EMA), gastrin, alpha-1-fetoprotein (AFP), keratin, and B72.3. Mucin-like materials occurred within cytoplasmic vacuoles.
authors.affiliation: Department of Veterinary Pathology, Faculty of Agriculture, Gifu University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yanai
authors.forename: T
authors.initials: T
authors.lastname: Masegi
authors.forename: M
authors.initials: M
authors.lastname: Hosoi
authors.forename: K
authors.initials: K
authors.lastname: Yamazoe
authors.forename: T
authors.initials: T
authors.lastname: Iwasaki
authors.forename: T
authors.initials: T
authors.lastname: Yagi
authors.forename: K
authors.initials: K
authors.lastname: Ueda
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D000818:Animals; D000836:Animals, Zoo; D002335:Carnivora; D005260:Female; D008854:Microscopy, Electron; D013274:Stomach Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*