Small-signal sensitivity of muscle spindles reinnervated after long-term denervation.
After long periods of denervation regenerated muscle spindle afferents show functional recovery despite gross histological abnormalities in their ending structure. This study prevents results examining the responses of such afferents to small amplitude stimuli, within the linear range of the spindle. The majority of regenerated afferents responded to the stimuli with a sensitivity similar to that of normal afferents.
Scott
J J
JJ
Department of Cell Physiology and Pharmacology, University of Leicester, UK.
Panesar
G
G
D000818:Animals; D002415:Cats; D009121:Muscle Denervation; D009470:Muscle Spindles / Q000502:physiology*; D018482:Muscle, Skeletal / Q000294:innervation; D009416:Nerve Regeneration / Q000187:drug effects / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*