title: Use of antigenic markers and genomic fingerprinting to study epidemiology of meningococcal disease.
abstract: The usefulness of the restriction enzyme fingerprinting was investigated for epidemiological studies of meningococci isolated from three patients who fell ill in meningococcal disease within a short period of time. The strains belonged to serogroup B and had similar serotype patterns. Epidemiological connections could not be excluded but genomic fingerprinting showed that the strains were probably of different origin. It is concluded that genomic fingerprinting is a potential and sensitive tool for epidemiological studies.
authors.affiliation: Department of Dermatology, University Hospital, Tromsø, Norway.
authors.forename: E S
authors.initials: ES
authors.lastname: Falk
mesh_terms: D000328:Adult; D000942:Antigens, Bacterial / Q000032:analysis*; D016172:DNA Fingerprinting; D004262:DNA Restriction Enzymes; D005260:Female; D016678:Genome; D006801:Humans; D008297:Male; D008585:Meningitis, Meningococcal / Q000453:epidemiology* / Q000235:genetics*; D012703:Serotyping
chemical_list: D000942:Antigens, Bacterial; D004262:DNA Restriction Enzymes