Expression of somatostatin receptor 3 mRNA in the motorneurones of the rat spinal cord, and the sensory neurones of the spinal ganglia.
At least five different types of somatostatin receptors (SSTRs): SSTR1-5 have been recently cloned. Here, we report the distribution of somatostatin receptor 3 (SSTR3) mRNA in spinal cord and spinal ganglia by in situ hybridization. We demonstrate the presence of this transcript in motorneurones of the spinal cord and other motor nuclei of the brain stem, and in the sensory neurones of the spinal ganglia. These data suggest a role for SSTR3 in motor and sensory functions.
Señaris
R M
RM
Department of Neurobiology, Babraham Institute, Cambridge, UK.
Schindler
M
M
Humphrey
P P
PP
Emson
P C
PC
D000818:Animals; D001933:Brain Stem / Q000378:metabolism; D005727:Ganglia, Spinal / Q000166:cytology / Q000378:metabolism*; D017403:In Situ Hybridization; D009046:Motor Neurons / Q000378:metabolism*; D009475:Neurons, Afferent / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000378:metabolism*; D051381:Rats; D017481:Receptors, Somatostatin / Q000235:genetics*; D013116:Spinal Cord / Q000166:cytology / Q000378:metabolism*; D014158:Transcription, Genetic
D012333:RNA, Messenger; D017481:Receptors, Somatostatin