Specific sorbent to remove solvent-detergent mixtures from virus-inactivated biological fluids.
A method involving a sorbent designed to capture specifically virus-inactivating solvent-detergent mixtures is described. Its specificity allows the adsorption of these undesirable chemicals with a high capacity in order to treat large amounts of inactivated biological fluids in small-sized columns. Typically, the volume of sorbent that can be used repeatedly is between one quarter and one tenth of the sample volume to be treated. Cleaning and sanitization can be done by classical methods while strong oxidizing agents can also be used to sterilize the sorbent.
Guerrier
L
L
BioSepra SA, Villeneuve la Garenne, France.
Flayeux
I
I
Boschetti
E
E
Radosevich
M B
MB
D001826:Body Fluids / Q000821:virology; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D003902:Detergents / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D012997:Solvents / Q000302:isolation & purification / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D014780:Viruses / Q000187:drug effects*
D003902:Detergents; D012997:Solvents