The effect of obesity on postmenopausal bone loss and the risk of osteoporosis.
There are many data indicating that osteoporotic fractures, and particularly hip fractures, are less frequent in obese subjects. Overweight and obese women have a higher bone mass after menopause than women of the same age who are not overweight, and thus in all probability have a slower bone loss. This protective effect appears to be related both to mechanical factors and to estrogen synthesis in adipose tissue.
Ribot
C
C
Endocrinology Department, C.H.U. Purpan, Toulouse, France.
Trémollières
F
F
Pouillès
J M
JM
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D015519:Bone Density / Q000502:physiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology*; D015663:Osteoporosis, Postmenopausal / Q000453:epidemiology* / Q000503:physiopathology*; D012307:Risk Factors