[Further study on the essence of acupoint specialty in mice].
Trace element, Cr+3 or V+5 are injected into acupoint of mice for pretreatment and then pentobarbital sodium injected into the same points, it is found that the element Cr+3 may shorten time of onset sleeping and prolong time of maintenance sleeping of injecting pentobarbital sodium at "Zusanli" point, while the element V+5 may shorten time of onset sleeping and prolong time of maintenance sleeping of injecting pentobarbital sodium at "Neigran" point. It indicates different trace elements can produce different influence on acupoint drug effect entering "Zusanli" or "Neiguan" point. The results mentioned above suggest that the different responses of different acupoints to same drug may be related to the different ion structures or different semi-conductive properties of the different acupoints.
Zhou
A
A
Dept. of Pharmacology, Nantong Medical College, Jiangsu Province, China.
Shao
Z
Z
Liu
Z
Z
D015669:Acupuncture Points; D000818:Animals; D002857:Chromium / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D010424:Pentobarbital / Q000494:pharmacology*; D014639:Vanadium / Q000494:pharmacology*
D014639:Vanadium; D002857:Chromium; D010424:Pentobarbital