title: Quantitation, mobilization, and clinical use of long-term culture-initiating cells in blood cell autografts.
abstract: Mobilized peripheral blood is increasingly used as a source of cells to provide hematopoietic reconstitution in marrow ablated patients. There is controversy as to how the engraftment potential of these preparations should be evaluated. The long-term culture-initiating cell is a very primitive hematopoietic with unique phenotypic feature. The potential role and significance of these cells in peripheral blood cell autografts is discussed.
authors.affiliation: Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, Canada.
authors.forename: H J
authors.initials: HJ
authors.lastname: Sutherland
authors.forename: D E
authors.initials: DE
authors.lastname: Hogge
authors.forename: P M
authors.initials: PM
authors.lastname: Lansdorp
authors.forename: G L
authors.initials: GL
authors.lastname: Phillips
authors.forename: A C
authors.initials: AC
authors.lastname: Eaves
authors.forename: C J
authors.initials: CJ
authors.lastname: Eaves
mesh_terms: D000818:Animals; D001773:Blood Cells / Q000637:transplantation*; D002454:Cell Differentiation; D002478:Cells, Cultured; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D014182:Transplantation, Autologous