A study of histology and enzymatic histochemistry on rabbit's retina in acute ocular hypertension.
The changes of activities of enzymes relating to energy metabolism in rabbit's retina in acute ocular hypertension were observed. The activities of succinate dehydrogenase and adenosine triphosphatase were found to be reduced, while the activities of the lactatic dehydrogenase and glucose-6-phosphatase increased. The results revealed the metabolic disturbance of energy in retina after acute ocular hypertension might be the underlying factors relating to the defects of the functions and structures of the retina.
Sun
W
W
Department of Ophthalmology, Affilliated Hospital of Qingdao Medical College, China.
Wang
S
S
Zhao
G
G
Gao
J
J
Liu
F
F
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009798:Ocular Hypertension / Q000201:enzymology* / Q000473:pathology; D011817:Rabbits; D012160:Retina / Q000201:enzymology* / Q000473:pathology; D013385:Succinate Dehydrogenase / Q000378:metabolism
D000255:Adenosine Triphosphate; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D005952:Glucose-6-Phosphatase