title: Structure-activity relationships of synthetic tigogenyl glycosides.
abstract: Haemolytic activities of the five tigogenyl diglycosides and a maltotrioside were much stronger than those of nine monoglycosides. Among these glycosides, the glucoside, galactoside, maltoside, lactoside, gentiobioside, melibioside and maltotrioside had strong antifungal activity. By contrast, none of these glycosides showed any antibacterial activity.
authors.affiliation: Faculty of Pharmaceutical Sciences, Kinki University, Higashiosaka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Takechi
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D002240:Carbohydrate Sequence; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology; D006460:Hemolysin Proteins / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D013150:Spirostans / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D006027:Glycosides; D006460:Hemolysin Proteins; D013150:Spirostans; C046297:sarsasapogenin