title: Anti-oral microbial activity of isoflavonoids in root bark of Ormosia monosperma.
abstract: From the root bark of Ormosia monosperma, 10 isoflavonoids including two new compounds 7,4'-dihydroxy-6",6"-dimethylpyrano-(2",3":5,6)-8-(3-methyl-1,3- butadienyl)isoflavone, named ormosidin, and dalbergion 4'-O-beta-D-glucopyranoside, were isolated. These structures were confirmed by spectroscopic analysis. 2,3-Dihydroauriculatin, one of the compounds isolated, showed moderate activities against oral-microbial organisms (Streptococcus mutans, Prophyromonas gingivalis and Actinomyces actinomycetemcomitans).
authors.affiliation: Department of Pharmacognosy, Gifu Pharmaceutical University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Iinuma
authors.forename: Y
authors.initials: Y
authors.lastname: Okawa
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: F C
authors.initials: FC
authors.lastname: Ho
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: K I
authors.initials: KI
authors.lastname: Miyauchi
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D008826:Microbial Sensitivity Tests; D010944:Plants / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000890:Anti-Infective Agents; D005960:Glucosides; D007529:Isoflavones; C091400:ormosidin; C091401:dalbergion 4'-O-glucopyranoside