title: Early recurrence of gastric cancer in a patient with chronic renal failure.
abstract: We report here a rare, rapid peritoneal recurrence after curative gastrectomy for gastric cancer occurred in a 51 year old woman who had been treated with hemodialysis due to chronic renal failure for 8 years. Preoperatively, her immune status was very low, as indicated by decreased natural killer cell activity and photohemagglutinin reaction and by increased immunosuppressive acidic protein. The density of S-100 positive intratumoral dendritic cells in the resected stomach was low, which also suggested a lower level of loco-regional immunity. Rapid progress of the recurrent disease and the poor prognosis might be related to the suppressed immune activity induced by a long-term chronic renal failure and hemodialysis. Thus, for patients with chronic renal failure who require resection of a gastric cancer, close follow-up is important.
authors.affiliation: Cancer Center of Kyushu University Hospital, Higashi-Ku Fukuoka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Endo
authors.forename: H
authors.initials: H
authors.lastname: Baba
authors.forename: S
authors.initials: S
authors.lastname: Ohno
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Maehara
authors.forename: K
authors.initials: K
authors.lastname: Sugimachi
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000276:immunology; D007694:Killer Cells, Natural / Q000276:immunology; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000150:complications / Q000276:immunology / Q000556:secondary*; D006435:Renal Dialysis; D013274:Stomach Neoplasms / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D013997:Time Factors