201T1-chloride uptake ratios in differentiating benign from malignant lesions: recommendations for ratio calculations and interpretation.
Thallium-201 (201T1) chloride ratios have been used to differentiate benign from malignant lesions in bones and soft tissues, brain, breast, lungs and thyroid. Different values of these ratios have been reported by various authors. The need to standardize the methods for calculating thallium ratios is discussed in this paper. The difference between calculating the ratios using planar and single photon emission tomography (SPET) images is presented in two patients who had metastatic bone lesions to the lower femoral condyle from non-Hodgkin's lymphoma and to the iliac bone from breast carcinoma. In our experience, it is more reliable to calculate the thallium ratios from SPET images whenever possible.
Abdel-Dayem
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Department of Radiology, St Vincent's Hospital and Medical Center, New York, New York 10011, USA.
D000368:Aged; D001847:Bone Diseases / Q000000981:diagnostic imaging; D001859:Bone Neoplasms / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D001941:Breast Diseases / Q000000981:diagnostic imaging; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D009369:Neoplasms / Q000000981:diagnostic imaging*; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging; D013793:Thallium / Q000493:pharmacokinetics*; D013794:Thallium Radioisotopes / Q000493:pharmacokinetics*; D013959:Thyroid Diseases / Q000000981:diagnostic imaging; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging; D015899:Tomography, Emission-Computed, Single-Photon
D013794:Thallium Radioisotopes; C027549:thallium chloride; D013793:Thallium