title: Neuropsychological investigations of multiple sclerosis: a clinical perspective.
abstract: Numerous research studies indicate that a subgroup of patients with multiple sclerosis (MS) experience cognitive and emotional deficits that correspond to degenerative brain changes. In some instances, neuropsychological impairment may be the initial and/or predominant symptom of MS. These observations underscore the need for neuropsychological evaluation as a critical component in the diagnostic evaluation and treatment of MS patients. In the current paper clinical issues relevant to the neuropsychological assessment of MS patients are reviewed and a proposal for comprehensive testing is presented.
authors.affiliation: Division of Behavioral Neurology, Beth Israel Hospital, Boston, MA 02215, USA.
authors.forename: M G
authors.initials: MG
authors.lastname: O'Connor
mesh_terms: D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000523:psychology; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests