[Panarteritis nodosa with kidney and spleen rupture: diagnostic and therapeutic possibilities].
Classic polyarteritis nodosa is a necrotizing vasculitis affecting medium- and small-sized arteries. Renal involvement from aneurysm formation is common and can result in perirenal or intrarenal bleeding. The gold standard of diagnostic procedures is the arteriography. Treatment of choice is a combination of steroids and cyclophosphamide, but in the case of severe hemorrhage surgery is mandatory. Patients with PAN need at least 2 years of long-term therapy; repeated arteriography will establish the efficacy of therapy.
Siebels
M
M
Medizinische Klinik, Universität Heidelberg.
Nöldge
G
G
Sanwald
R
R
Andrassy
K
K
D000328:Adult; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D008297:Male; D010488:Polyarteritis Nodosa / Q000175:diagnosis* / Q000628:therapy*; D012421:Rupture; D013158:Splenic Diseases / Q000150:complications
Panarteriitis nodosa mit Nieren- und Milzruptur: diagnostische und therapeutische Möglichkeiten.