title: Molecular recognition in DNA-binding proteins and enzymes.
abstract: The molecular basis for the specificity and activity of protein-DNA interactions is currently being established from the combination of results on the structure and biochemistry of DNA-binding proteins and enzymes. Data detailed in the 12 most recent studies on DNA-binding protein and enzyme structures, including the major advances in the elucidation of enzyme-mediated DNA-repair processes, have both increased understanding of DNA recognition and enhanced prospects for the design of novel DNA-binding proteins in the future.
authors.affiliation: Department of Molecular Biology, Scripps Research Institute, La Jolla, California 92037.
authors.forename: J A
authors.initials: JA
authors.lastname: Tainer
authors.forename: R P
authors.initials: RP
authors.lastname: Cunningham
mesh_terms: D001709:Biotechnology; D004268:DNA-Binding Proteins / Q000737:chemistry*; D004798:Enzymes / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D011485:Protein Binding; D011487:Protein Conformation
chemical_list: D004268:DNA-Binding Proteins; D004798:Enzymes