title: [Alanine aminotransferase--a surrogate marker of viral hepatitis].
abstract: Examinations of 4457 blood donors (about 80% were men aged 18 to 30) revealed an increased level of serum glutamic-pyruvic transaminase (SGPT) in 82 (1.8%). Specific markers of viral hepatitis C were detected in 15.9%, of hepatitis B in 12.0%, of hepatitis D in 2.0%, of hepatitis E in 8.0%, of hepatitis A in 2.0% of sera with high SGPT levels. Mandatory screening of blood donors revealed specific markers of viral hepatitis in 15.9% of cases, additional testing detected these markers in 10.9% cases more. A conclusion is made that an increase of SGPT activity is an independent surrogate marker of viral hepatitis.
authors.forename: E B
authors.initials: EB
authors.lastname: Zhiburt
authors.forename: N V
authors.initials: NV
authors.lastname: Bel'gesov
authors.forename: T N
authors.initials: TN
authors.lastname: Vashchenko
authors.forename: I G
authors.initials: IG
authors.lastname: Bondarenko
authors.forename: V S
authors.initials: VS
authors.lastname: Tokmakov
authors.forename: V B
authors.initials: VB
authors.lastname: Vasiliuk
mesh_terms: D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000032:analysis*; D015415:Biomarkers / Q000032:analysis*; D006505:Hepatitis / Q000201:enzymology*; D006801:Humans; D008297:Male
chemical_list: D015415:Biomarkers; D000410:Alanine Transaminase
vernacular_title: Alaninaminotransferaza--surrogatnyĭ marker virusnogo gepatita.