title: Prevention of hepatitis C infection in haemodialysis units. A prospective study.
abstract: A prospective study was begun in our haemodialysis unit after four previously negative patients were found to be anti-HCV positive. A dedicated area and dedicated dialysis equipment (but not a separate room) were assigned to anti-HCV-positive patients and testing for HCV antibodies was performed every 3 months. A total of 131 patients were treated during the study period of 18 months. Of these, 50 patients were dialysed during the entire 18 months, and 21 were available to be tested six or more months after having left the centre. During the first 6 weeks after implementing the precautions two more anti-HCV-positive patients were detected. However, during the rest of the study period no further newly infected patients were found. It is concluded that the spread of HCV infection in a haemodialysis environment can be prevented by limited isolation procedures.
authors.affiliation: Department of Medicine, Kantonsspital Aarau, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Blumberg
authors.forename: C
authors.initials: C
authors.lastname: Zehnder
authors.forename: J J
authors.initials: JJ
authors.lastname: Burckhardt
mesh_terms: D058186:Acute Kidney Injury / Q000150:complications / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000517:prevention & control*; D005260:Female; D006436:Hemodialysis Units, Hospital; D006526:Hepatitis C / Q000175:diagnosis / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010356:Patient Isolation / Q000379:methods; D011446:Prospective Studies; D006435:Renal Dialysis