title: Management of meconium aspiration syndrome by tracheobronchial lavage and replacement of Surfactant-TA.
abstract: Meconium aspiration syndrome creates mechanical airway obstruction with air trapping and atelectasis. Tracheobronchial saline lavage to dislodge meconium may precipitate respiratory distress, a wet lung appearance and respiratory failure. Two case studies are reported in which meconium aspiration resulted in mechanical obstruction and displacement of surfactant and in whom tracheobronchial saline lavage and artificial surfactant replacement reversed respiratory failure.
authors.affiliation: Perinatal Medical Center, Kagoshima Municipal Hospital, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ibara
authors.forename: T
authors.initials: T
authors.lastname: Ikenoue
authors.forename: Y
authors.initials: Y
authors.lastname: Murata
authors.forename: H
authors.initials: H
authors.lastname: Sakamoto
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamura
authors.forename: H
authors.initials: H
authors.lastname: Asano
authors.forename: T
authors.initials: T
authors.lastname: Hirano
authors.forename: K
authors.initials: K
authors.lastname: Kuraya
authors.forename: H
authors.initials: H
authors.lastname: Maruyama
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007442:Intubation, Intratracheal; D008297:Male; D008471:Meconium Aspiration Syndrome / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D011663:Pulmonary Surfactants / Q000008:administration & dosage* / Q000172:deficiency; D012123:Pulmonary Ventilation; D011859:Radiography; D012131:Respiratory Insufficiency / Q000628:therapy*; D007507:Therapeutic Irrigation
chemical_list: D011663:Pulmonary Surfactants