[Acute kidney failure in the patient with multiple myeloma. An analysis of the authors' personal cases].
The renal involvement in a multiple myeloma case (MM) has a frequency of 50% and causes a worsening of the disease with a survival average of about 12 months. Myeloma cast nephropathy (MCN) represents the more frequent clinic, histological form of nephropathy in course of MM and it evolves when monoclonal light free chain deposit in the renal tubules together with some other worse cases like dehydration and/or hypercalcaemia. We analyze here the clinical and renal histological features of eight patients treated for acute renal failure found in MCN in course of MM grade B. This was discovered through renal bioptic check-up. We have evaluated the Bence-Jones proteinuria, the recurrence of the condition of risk and the course of the renal failure of these patients also in order to treat the hematological illness.
Vivaldi
P
P
UO Medicina 2a, Ospedale S. Chiara, Trento.
Comotti
C
C
Prevedello
C
C
Rovati
C
C
D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology*; D000368:Aged; D000369:Aged, 80 and over; D001536:Bence Jones Protein / Q000032:analysis; D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis
D001536:Bence Jones Protein; D003404:Creatinine
L'insufficienza renale acuta del paziente con mieloma multiplo. Analisi di una casistica personale.