[Immunoscintigraphy of bone marrow in plasmacytoma].
In 26 patients with plasmocytoma and 4 patients with benign monoclonal gammopathy bone marrow scintigraphy using 99mTc-labelled monoclonal antigranulocyte-antibodies was performed. Focal marrow defects were found in 18/26 patients with plasmocytoma but in none with benign monoclonal gammopathy. The results in plasmocytoma patients correlated well with the clinical staging system of Durie and Salmon. Quantification showed a suppressed bone marrow uptake ratio in 8/26 patients. A marked bone marrow expansion was present in only 2/26 patients. Bone marrow scintigraphy seems to be a valuable diagnostic tool in patients with plasmocytoma, especially as it is able to visualize the degree of bone marrow infiltration in a single protocol and so allows to follow up patients in a simple noninvasive manner.
Bathmann
J
J
Radiologischen Universitätsklinik, Abteilung Nuklearmedizin, Klinikums der Albert-Ludwigs-Universität, Freiburg/Br., FRG.
Brugger
W
W
Ullrich
C
C
Mertelsmann
R
R
Moser
E
E
D000911:Antibodies, Monoclonal; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D006801:Humans; D009367:Neoplasm Staging; D010265:Paraproteinemias / Q000000981:diagnostic imaging*; D010954:Plasmacytoma / Q000000981:diagnostic imaging* / Q000473:pathology; D016719:Radioimmunodetection / Q000379:methods*; D013667:Technetium
D000911:Antibodies, Monoclonal; D013667:Technetium
Immunszintigraphie des Knochenmarks beim Plasmozytom.