Engineering proteins for environmental applications.
Recently, significant new insight has been obtained into the structure and catalytic mechanism of enzymes that convert environmental pollutants. Recent advances in protein engineering make it possible to use this information for improving the catalytic performance of such enzymes to achieve increased stability and expanded substrate range.
Janssen
D B
DB
Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology, University of Groningen, The Netherlands.
Schanstra
J P
JP
D001419:Bacteria / Q000201:enzymology / Q000235:genetics; D001673:Biodegradation, Environmental; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004777:Environment; D004785:Environmental Pollutants; D004798:Enzymes / Q000096:biosynthesis / Q000378:metabolism*; D006867:Hydrolases / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism; D010105:Oxygenases / Q000378:metabolism; D015202:Protein Engineering; D014366:Tryptophan Oxygenase / Q000378:metabolism
D004785:Environmental Pollutants; D004798:Enzymes; D003577:Cytochrome P-450 Enzyme System; D010088:Oxidoreductases; D010105:Oxygenases; D014366:Tryptophan Oxygenase; C044391:ligninase; D006867:Hydrolases