Genetic modulation in the pathogenesis and treatment of cancer.
Recent advances in molecular biology have improved our understanding of the pathogenesis of cancer. Molecular genetic alterations have been characterized in lung and esophageal tumors, and have potential clinical application in tumor diagnosis, staging, prevention, and therapy.
Casson
A G
AG
Department of Surgery, University of Toronto Faculty of Medicine, Ontario, Canada.
McCart
J A
JA
D004273:DNA, Neoplasm / Q000032:analysis; D004938:Esophageal Neoplasms / Q000209:etiology / Q000235:genetics* / Q000628:therapy; D016147:Genes, Tumor Suppressor / Q000235:genetics; D005815:Genetic Code; D005819:Genetic Markers; D005821:Genetic Techniques; D015316:Genetic Therapy; D006801:Humans; D009369:Neoplasms / Q000209:etiology / Q000235:genetics* / Q000628:therapy; D009857:Oncogenes / Q000235:genetics
D004273:DNA, Neoplasm; D005819:Genetic Markers