[The coupling of the contrariwise changes in the steroid-secreting activity of the adrenals and the steroid-metabolizing activity of the liver in rats after x-ray irradiation].
The rat adrenal cortex activation is accompanied by inhibition of steroid metabolism in liver and vice versa at acute radiation disease caused by X-ray irradiation. A coupling of contrary changes of corticosteroid secretion and metabolism evidences that there is common regulation of these functions. The possible ACTH participation in coupling of adrenals and liver functions and the liver role in radiation hypercorticism genesis are discussed.
Litskevich
L A
LA
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000208:Acute Disease; D000302:Adrenal Cortex / Q000378:metabolism / Q000528:radiation effects*; D000305:Adrenal Cortex Hormones / Q000378:metabolism / Q000528:radiation effects*; D000308:Adrenocortical Hyperfunction / Q000209:etiology / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000502:physiology / Q000528:radiation effects; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D008099:Liver / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D011833:Radiation Injuries, Experimental / Q000209:etiology / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D015062:11-Hydroxycorticosteroids; D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone
Sopriazhennost' protivonapravlennykh izmeneniĭ steroidsekretiruiushcheĭ aktivnosti nadpochechnikov i steroidmetaboliziruiushcheĭ aktivnosti pecheni krys pri rentgenovskom obluchenii.