A new cytotoxic dihydroxy sterol from the soft coral Alcyonium patagonicum.
A new sterol, 24-methylenecholest-4-ene-3 beta,6 beta-diol [1] was isolated from the soft coral Alcyonium patagonicum collected from the South China Sea. Its structure was determined by spectral analysis. Compound 1 was cytotoxic against the P-388 cell line with an IC50 value of 1 microgram/ml.
Zeng
L
L
Department of Chemistry, Zhongshan University, Guangzhou, People's Republic of China.
Li
X
X
Su
J
J
Fu
X
X
Schmitz
F J
FJ
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002776:Cholestanes / Q000302:isolation & purification* / Q000494:pharmacology; D003063:Cnidaria / Q000737:chemistry*; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice; D014407:Tumor Cells, Cultured
C093891:24-methylenecholest-4-ene-3,6-diol; D000970:Antineoplastic Agents; D002776:Cholestanes