title: Cytokines, inflammation, and autoimmune diseases.
abstract: The understanding of cytokines is in its infancy, but it appears that overproduction or deficiency of these intracellular mediators may contribute to inflammatory and autoimmune diseases such as insulin-dependent diabetes mellitus and rheumatoid arthritis. As the complexities of cytokine actions and interactions are unraveled, therapeutic blockade or upregulation may be possible.
authors.affiliation: Department of Pathology, University of Michigan Medical School, Ann Arbor, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Ward
mesh_terms: D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000276:immunology / Q000628:therapy; D001327:Autoimmune Diseases / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D016207:Cytokines / Q000276:immunology*; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology / Q000276:immunology / Q000628:therapy; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000276:immunology* / Q000628:therapy
chemical_list: D016207:Cytokines