title: Neosiphoniamolide A, a novel cyclodepsipeptide, with antifungal activity from the marine sponge Neosiphonia superstes.
abstract: A novel cyclodepsipeptide, neosiphoniamolide A [1], has been isolated from the sponge Neosiphonia superstes. The structure of 1, which contains a 12-carbon hydroxy acid, glycine, valine, and a halogenated tyrosine residue in an 18-membered ring, is related to jaspamide and the geodiamolides, previously isolated from sponges. The structure was solved by spectroscopic analysis.
authors.affiliation: Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Italy.
authors.forename: M V
authors.initials: MV
authors.lastname: D'Auria
authors.forename: L
authors.initials: L
authors.lastname: Gomez Paloma
authors.forename: L
authors.initials: L
authors.lastname: Minale
authors.forename: A
authors.initials: A
authors.lastname: Zampella
authors.forename: C
authors.initials: C
authors.lastname: Debitus
authors.forename: J
authors.initials: J
authors.lastname: Perez
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011161:Porifera / Q000737:chemistry*
chemical_list: D000935:Antifungal Agents; D010456:Peptides, Cyclic; C093764:neosiphoniamolide A