Exanthem subitum (roseola infantum) with vesicular lesions.
We report a 7-month-old boy who developed vesicular lesions during the course of exanthem subitum. Human herpesvirus-6 (HHV-6) DNA was detected both in the skin lesions and in the throat, by polymerase chain reaction. IgG and IgM antibodies against HHV-6 were 1:10 and < 1:10, respectively on the tenth day of the illness, and > 1:640 and 1:10 on the twenty-second day, respectively. These results suggest that this was primary HHV-6 infection.
Yoshida
M
M
Department of Dermatology, School of Medicine, Kinki University, Osaka, Japan.
Fukui
K
K
Orita
T
T
Kusuda
S
S
Tezuka
T
T
Hiruma
M
M
D000914:Antibodies, Viral / Q000032:analysis; D001768:Blister / Q000473:pathology*; D004279:DNA, Viral / Q000032:analysis; D005077:Exanthema Subitum / Q000382:microbiology / Q000473:pathology*; D015654:Herpesvirus 6, Human / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D004279:DNA, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M