title: [Vogt-Koyanagi-Harada disease complicated by subretinal neovessels].
abstract: A 22 year-old woman with bilateral retinal detachment in Vogt-Koyanagi-Harada syndrome was observed 9 months after the onset of symptoms with subretinal neovascularization in both eyes. The new vessels were located in the peripapillary and extrafoveal regions; they were elevated, grey-white. The new vessels occurred in areas of pigmentary disturbances (hyperpigmentation) and damages of the Bruch's membrane. We discuss chronic recurrent phase of inflammation, marked of predominantly anterior chamber, and fundus hyperpiomentary disturbances as risk factors associated with the development of subretinal neovascular membranes in Vogt-Koyanagi-Harada disease.
authors.affiliation: Service d'Ophthalmologie, Hôpital Bichat-Claude-Bernard, Paris.
authors.forename: N
authors.initials: N
authors.lastname: Lepvrier-Guibal
authors.forename: J F
authors.initials: JF
authors.lastname: Korobelnik
authors.forename: T H
authors.initials: TH
authors.lastname: Xuan
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D012163:Retinal Detachment / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D015861:Retinal Neovascularization / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D011241:Prednisone
vernacular_title: Maladie de Vogt-Koyanagi-Harada compliquée de néovaisseaux sous-rétiniens.