[Bacterial vaginosis during chemotherapy for gynecological neoplasms. A therapeutic proposal].
Bacterial vaginosis (BV) is a well characterized disease, defined Amsel's criteria, whose incidence is significantly increased during chemotherapy for gynecologic malignancies, as previously reported by the authors. Nine patients out of 14 (64%) who were receiving adjuvant chemotherapy for gynecologic tumors showed a clinical and laboratory evidence of bacterial vaginosis and were treated with cetyltrimethilammonium naproxenate vaginal douches. Results were analyzed up to the completion of oncologic chemotherapy: a high efficacy and tolerability for the topical treatment was demonstrated in all cases.
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Clinica Ostetrica e Ginecologica, Università degli Studi, L'Aquila.
Di Stefano
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Mascaretti
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D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002593:Cetrimonium Compounds / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D004341:Drug Evaluation; D005260:Female; D006194:Gardnerella vaginalis / Q000302:isolation & purification; D005833:Genital Neoplasms, Female / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008875:Middle Aged; D009288:Naproxen / Q000031:analogs & derivatives / Q000627:therapeutic use; D016585:Vaginosis, Bacterial / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology
D002593:Cetrimonium Compounds; C093881:cetyltrimethylammonium naproxenate; D009288:Naproxen
La vaginosi batterica in corso di chemioterapia per tumori ginecologici. Proposta terapeutica.