Obesity-related hypertension: mechanisms, cardiovascular risks, and heredity.
Recent investigations cast some doubts on the status of insulin resistance as a trigger in hyperinsulinemia-associated hypertension or obesity-related hypertension, or both. Major epidemiological studies have shown that central adiposity is a powerful risk factor for stroke or coronary artery disease when accompanied by hypertension or hypertriglyceridemia. New heredity studies have failed to identify a common gene that may explain obesity-related hypertension.
Reisin
E
E
Department of Medicine, Louisiana State University Medical Center, New Orleans, USA.
Messerli
F H
FH
D000818:Animals; D002319:Cardiovascular System / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology; D009765:Obesity / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D012307:Risk Factors