title: Outcome of renal transplant recipients in the ICU.
abstract: OBJECTIVE
  To determine the outcome of renal transplant recipients in an intensive care unit (ICU).
  
  
  METHODS
  Prospective, cohort study.
  
  
  METHODS
  Surgical ICU in a tertiary care hospital.
  
  
  METHODS
  Consecutive adult renal transplant recipients admitted to an ICU.
  
  
  RESULTS
  Demographic data, underlying diseases, indications for admission to the ICU, number of prior kidney transplantations, duration of immunosuppression, duration of mechanical ventilation, length of stay in ICU and hospital, and ICU and hospital mortality were recorded. Seventy-one patients were included in the study. Twenty-seven patients were admitted to the surgical ICU immediately after renal transplantation surgery for postoperative monitoring (group 1). One patient died in this group. The remaining 44 patients were renal transplant recipients admitted to the surgical ICU with various complications (group 2). The mean posttransplant time in group 2 was 23 +/- 30 months. Seven patients died in group 2. The overall ICU mortality in this study was 11% and hospital mortality was 14%. The hospital mortality for postoperative patients (3.7% in group 1) was below the rate predicted based on the acute physiology and chronic health evaluation (APACHE II) score (15%). APACHE II score, duration of mechanical ventilation, and ICU length of stay were significantly higher among nonsurvivors. The ICU mortality among renal transplant recipients was higher than that of other patients (6%) admitted to the surgical ICU during the study period.
  
  
  CONCLUSIONS
  The ICU mortality of renal transplant recipients was twice that of general surgical ICU patients. The hospital mortality rate for recipients admitted immediately postoperatively to the ICU (group 1) was less than predicted by APACHE II.
authors.affiliation: Department of Anesthesiology/Critical Care, University of Pittsburgh Medical Center, Presbyterian-University Hospital, USA.
authors.forename: H
authors.initials: H
authors.lastname: Sadaghdar
authors.forename: L
authors.initials: L
authors.lastname: Chelluri
authors.forename: S A
authors.initials: SA
authors.lastname: Bowles
authors.forename: R
authors.initials: R
authors.lastname: Shapiro
mesh_terms: D018806:APACHE; D003422:Critical Care; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D016030:Kidney Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies