Delayed radioiodine organification in Plummer's disease.
Hyperfunctioning thyroid adenomas causing thyrotoxicosis (Plummer's disease) is not an uncommon cause of hyperthyroidism in the elderly. Most commonly, the adenoma appears as a so-called "hot" nodule on thyroid scintigraphy causing suppression (i.e., nonvisualization) of the remainder of the gland. This report describes a case of Plummer's disease in an elderly patient in whom the toxic nodule primarily responsible for causing the hyperthyroidism became scintigraphically apparent at 96 hours after I-131 therapeutic ablation.
Intenzo
C M
CM
Department of Radiation Oncology and Nuclear Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA.
Park
C H
CH
Kim
S M
SM
D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D000368:Aged; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D013961:Thyroid Gland / Q000000981:diagnostic imaging*; D013964:Thyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D013971:Thyrotoxicosis / Q000000981:diagnostic imaging* / Q000209:etiology; D013997:Time Factors
D007457:Iodine Radioisotopes; D013670:Sodium Pertechnetate Tc 99m