title: A prospective, controlled evaluation of home chemotherapy for children with cancer.
abstract: OBJECTIVE
  Infusion of chemotherapy at home provides an alternative to hospitalization for children with cancer. Few programs of pediatric home chemotherapy have been described or evaluated. The purpose of this work was to compare prospectively chemotherapy in the hospital to chemotherapy at home with respect to billed medical charges, out-of-pocket expenses, and quality of life.
  
  
  METHODS
  Eligibility criteria for home therapy were defined. Parents and nurses were trained. Billed charges, loss of wages, out-of-pocket expenses, medical outcome, and quality of life of 14 patients for one course of chemotherapy in the hospital were compared with those for an identical course at home.
  
  
  RESULTS
  Daily charges for chemotherapy were $2329 +/- 627 in the hospital and $1865 +/- 833 at home; out-of-pocket costs, $68 +/- 31 and $11 +/- 6, respectively; and loss of income, $265 +/- 233 and $67 +/- 107, respectively. Patients' independence, well-being, appetite, mood, and school work were significantly better at home, and parental time at work and with the family was greater.
  
  
  CONCLUSIONS
  Administration of selected chemotherapy at home results in lower billed charges, reduced expenses, reduced loss of income for parents, and a more satisfying lifestyle for patients and parents.
authors.affiliation: Department of Pediatrics, Hershey Medical Center, PA 17033, USA.
authors.forename: P
authors.initials: P
authors.lastname: Close
authors.forename: E
authors.initials: E
authors.lastname: Burkey
authors.forename: A
authors.initials: A
authors.lastname: Kazak
authors.forename: P
authors.initials: P
authors.lastname: Danz
authors.forename: B
authors.initials: B
authors.lastname: Lange
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000191:economics*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000191:economics; D002648:Child; D002675:Child, Preschool; D017281:Cost of Illness; D004608:Eligibility Determination; D005249:Fees and Charges; D005260:Female; D018718:Home Infusion Therapy / Q000191:economics*; D017722:Hospital Charges; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D015143:Philadelphia; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy; D011446:Prospective Studies; D011788:Quality of Life
chemical_list: D000970:Antineoplastic Agents