title: [A case of beneficial effect of ulinastatin on postoperative renal function in a patient with acute renal failure].
abstract: We experienced a case in which ulinastatin may have been beneficial to improve postoperative renal function in a patient with acute renal failure. The patient had acute renal failure with serum Cr of 9.3 mg.dl-1 after nephrectomy. On the 14th postoperative day, he underwent laparotomy under diagnosis of ileus. Administration of ulinastatin, 300,000 units.day-1 for 4 days, increased urine volume and creatine clearance and improved serum Cr level. This case suggests that ulinastatin might exert a beneficial effect on the recovery from renal tubular damage and on the glomerular filtration ratio, with resultant improvement of acute renal failure.
authors.affiliation: Department of Anesthesiology and Emergency Medicine, Kagawa Medical School.
authors.forename: M
authors.initials: M
authors.lastname: Ueki
authors.forename: S
authors.initials: S
authors.lastname: Yokono
authors.forename: J
authors.initials: J
authors.lastname: Nogaya
authors.forename: S
authors.initials: S
authors.lastname: Taie
authors.forename: H
authors.initials: H
authors.lastname: Komatsu
authors.forename: K
authors.initials: K
authors.lastname: Ogli
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000503:physiopathology; D000368:Aged; D006023:Glycoproteins / Q000627:therapeutic use*; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000503:physiopathology; D007680:Kidney Neoplasms / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D011183:Postoperative Complications / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D006023:Glycoproteins; C028665:urinastatin