An automated [15Q]H2O production and injection system for PET imaging.
A computer controlled [15O]H2O injection system has been designed for multiple bolus injections during PET cerebral blood flow studies. The system is housed in a lead safe, and radiation exposure to nearby personnel is low; we have measured rates of approx. 100 microSv/h (10 mR/h) during 2 min of [15O]H2O production and < 50 microSv/h (< 5 mR/h) after 3.7 GBq (100 mCi) has been produced. Reproducibility studies show that the injected activity varies with a coefficient of variation of 2-3%.
Palmer
B M
BM
PET Imaging Service, VA Medical Center, Minneapolis, MN 55417, USA.
Sajjad
M
M
Rottenberg
D A
DA
D001331:Automation / Q000295:instrumentation / Q000379:methods; D002560:Cerebrovascular Circulation; D017357:Cyclotrons; D006801:Humans; D007553:Isotope Labeling / Q000295:instrumentation / Q000379:methods; D008838:Microcomputers; D010104:Oxygen Radioisotopes; D012984:Software; D013997:Time Factors; D014055:Tomography, Emission-Computed; D014867:Water
D010104:Oxygen Radioisotopes; D014867:Water