[Clinical significance of c-myc gene in esophageal squamous cell carcinoma].
Using polymerase chain reaction, we analysed 41 samples of esophageal squamous cell cancer at molecular level. Amplification of c-myc gene was found in 16 (39%). C-myc gene amplification was found to be related to lymph node metastasis, TNM staging (P < 0.01) and also prognosis (P < 0.05). We thought that c-myc gene was the prognosis factor for the patients with esophageal squamous cell carcinoma.
He
J
J
Department of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhang
R G
RG
Zhu
D
D
D000328:Adult; D000368:Aged; D001483:Base Sequence; D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000556:secondary; D004938:Esophageal Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D016259:Genes, myc; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011379:Prognosis