Carbohydrate metabolism in hepatic tissue of freshwater catfish Clarias batrachus L. during dimethoate exposure.
Clarias batrachus L., a freshwater catfish of commercial importance, was exposed to a sublethal concentration of dimethoate (Rogor). The acute effect of dimethoate on some aspects of carbohydrate metabolism of hepatic tissue was studied after 1, 2, 4 and 8 days. The glycogen content was depleted, whereas the lactate level was elevated throughout the experimental period and an increase in lactate dehydrogenase was observed. The activity levels of glycogen phosphorylase a and ab in the hepatic tissue were increased during dimethoate stress. The results suggest that carbohydrate metabolism was adversely affected in the hepatic tissue by the organophosphate insecticide dimethoate.
Begum
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Department of Zoology, Osmania University, Hyderabad, India.
Vijayaraghavan
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D000818:Animals; D050260:Carbohydrate Metabolism; D002397:Catfishes / Q000378:metabolism*; D004117:Dimethoate / Q000633:toxicity*; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D014874:Water Pollutants, Chemical; D004117:Dimethoate