title: TLC of p-nitroanilines and their analogues with cyclodextrins in the mobile phase.
abstract: The addition of alpha-, beta-, gamma-, and hydroxypropyl-beta-cyclodextrins to aqueous mobile phases can be used to enhance the migration of p-nitroanilines and their analogues on thin-layer chromatography. Urea, which is used to solubilize the cyclodextrins in aqueous solutions, is also found to increase the migration of these compounds. The equilibrium binding constants for the solute-cyclodextrin complexes formed in the mobile phase are determined. The results obtained using either silica gel or polyamide plates are similar.
authors.affiliation: Department of Chemistry, Xavier University of Louisiana, New Orleans 70125, USA.
authors.forename: I R
authors.initials: IR
authors.lastname: Politzer
authors.forename: K T
authors.initials: KT
authors.lastname: Crago
authors.forename: T
authors.initials: T
authors.lastname: Hollin
authors.forename: M
authors.initials: M
authors.lastname: Young
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry / Q000302:isolation & purification*; D002855:Chromatography, Thin Layer; D003505:Cyclodextrins / Q000737:chemistry; D015394:Molecular Structure; D014508:Urea
chemical_list: D000814:Aniline Compounds; D003505:Cyclodextrins; C019498:4-nitroaniline; D014508:Urea