title: Structure of malformin B, a phytotoxic metabolite produced by Aspergillus niger.
abstract: Malformin B, produced by Aspergillus niger, was separated into six compounds by HPLC. Their structures were determined by amino acid analyses, and by mass spectral and two-dimensional NMR experiments to be cyclic pentapeptides structurally related to malformin A1. Both the NMR and MS/MS experiments suggest cyclo-D-cysteinyl-D-cysteinyl-L-amino acid-D-amino acid-L-amino acid as the essential structure of malformins.
authors.affiliation: Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.
authors.forename: K W
authors.initials: KW
authors.lastname: Kim
authors.forename: F
authors.initials: F
authors.lastname: Sugawara
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
authors.forename: N
authors.initials: N
authors.lastname: Murofushi
authors.forename: N
authors.initials: N
authors.lastname: Takahashi
authors.forename: R W
authors.initials: RW
authors.lastname: Curtis
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001234:Aspergillus niger / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000096:biosynthesis / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000596:Amino Acids; D010456:Peptides, Cyclic; C001675:malformins