Oral manifestations of alpha-mannosidosis: report of a case with ultrastructural findings.
Alpha-mannosidosis is a rare storage disease with distinct biochemical, clinical, histological and ultrastructural features. The oro-facial findings in a 26-year-old man are described. Gingival and oral mucosal hyperplasias were studied using histology and transmission electron microscopy (TEM). The TEM findings were comparable to those of other tissues examined in previous reports, consisting of histiocytic cells containing storage vacuoles with fine reticulo-granular material.
Ishigami
T
T
First Department of Oral and Maxillofacial Surgery, Kagoshima, University Dental School, Japan.
Schmidt-Westhausen
A
A
Philipsen
H P
HP
Baiborodin
S I
SI
Gelderblom
H
H
Reichart
P A
PA
D000328:Adult; D002508:Cephalometry; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005145:Face / Q000002:abnormalities; D015726:Giant Cells / Q000648:ultrastructure; D005885:Gingival Hyperplasia / Q000209:etiology* / Q000473:pathology; D006644:Histiocytes / Q000648:ultrastructure; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000209:etiology* / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology / Q000648:ultrastructure; D008363:alpha-Mannosidosis / Q000150:complications / Q000473:pathology*