Marine algae that display anti-tumorigenic activity against Agrobacterium tumefaciens.
Thirty-five extracts representing different seasonal growths of 17 marine algal species collected from the Alexandria coast were tested for anti-tumorigenic activity against Agrobacterium tumefaciens galls on potato discs. Eleven extracts (nine species) displayed > 20% inhibition of tumor initiation, with three of these (Codium tomentosum, winter; Jania rubens, summer; Padina pavonia, winter) displaying relatively high activity. Bacterial viability tests showed that the inhibitory effects were directly due to anti-tumorigenesis rather than an indirect result of anti-bacterial activity.
el-Masry
M H
MH
Department of Bioscience and Technology, University of Alexandria, Egypt.
Mostafa
M H
MH
Ibrahim
A M
AM
el-Naggar
M M
MM
D016960:Agrobacterium tumefaciens / Q000187:drug effects*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D056890:Eukaryota / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology; D010941:Plant Tumors / Q000382:microbiology*; D012623:Seawater; D011198:Solanum tuberosum
D000970:Antineoplastic Agents; D010936:Plant Extracts