The in-vitro effect of temperature on MICs, bactericidal rates and postantibiotic effects in Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa.
Varying temperatures (35.5 degrees C, 38.5 degrees C, 41 degrees C) only minimally affected growth rates in vitro of Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa, as well as bactericidal rates and postantibiotic effects of several antibiotics. However, MICs were reduced at least four-fold by increasing temperature in 25% of the drug-organism combinations tested.
Magnusson
V
V
Department of Clinical Microbiology, Borgarspitalinn (Reykjavik City Hospital), Iceland.
Jonsdottir
T
T
Gudmundsdottir
H
H
Erlendsdottir
H
H
Gudmundsson
S
S
D001431:Bacteriological Techniques; D004352:Drug Resistance, Microbial; D006358:Hot Temperature; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000502:physiology; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000502:physiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000502:physiology