[The effect of ketalar on fatty acid metabolism in the myocardium].
The intraperitoneal administration of ketalar in a dose of 50 mg/kg elevated the myocardial levels of triglycerides, reduced non-esterified fatty acids and enhanced uncontrolled mitochondrial respiration during oxidation of caprylate and palmitoylcarnitine. The efficiency of phosphorylation remained unchanged.
Abidova
S S
SS
Ovchinnikov
I V
IV
Gimmel'farb
G N
GN
D000818:Animals; D002855:Chromatography, Thin Layer; D004734:Energy Metabolism / Q000187:drug effects; D005227:Fatty Acids / Q000032:analysis / Q000378:metabolism*; D007649:Ketamine / Q000494:pharmacology*; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis; D008297:Male; D008929:Mitochondria, Heart / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
D005227:Fatty Acids; D008055:Lipids; D007649:Ketamine
Vliianie ketalara na metabolizm zhirnykh kislot v miokarde.