title: [Clinical studies on SY5555 in pediatrics].
abstract: SY5555 in dry syrup (powder which is dissolved before use) or tablet form was given orally to 21 children with acute bacterial infections including 4 with acute pharyngitis, 5 with acute tonsillitis, 7 with acute bronchitis, 2 with acute gastroenteritis, 1 each with scarlet fever, acute lymphadenitis and urinary tract infection. Good to excellent clinical responses were obtained in all of the 21 patients and 8 of 11 strains found as causative organisms in these cases were eradicated and 3 strains were decreased. Loose stools were observed in 3 cases and eosinophilia was observed in 1 case. From the above clinical results, it appears that SY5555 is a useful antibiotic for the treatment of pediatric patients with various bacterial infections.
authors.affiliation: Department of Pediatrics, Takamatsu Red Cross Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Sekiguchi
authors.forename: T
authors.initials: T
authors.lastname: Okamoto
mesh_terms: D000284:Administration, Oral; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D015780:Carbapenems / Q000008:administration & dosage* / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011208:Powders; D013607:Tablets
chemical_list: D015780:Carbapenems; D011208:Powders; D013607:Tablets; C060114:SUN 5555