Inclusion body myositis presenting with isolated erector spinae paresis.
We report a 70-year-old patient who presented with a 4-year history of weakness of paravertebral muscles. Electrodiagnostic studies revealed a mixed neurogenic-myopathic pattern. Light microscopic examination revealed atrophic fibers with rimmed vacuoles; electron microscopy demonstrated cytoplasmic and intranuclear filaments measuring about 16 nm in width, consistent with the diagnosis of inclusion body myositis. Therapy with corticosteroids provided only a mild and transient benefit. Ten months after the initial evaluation, clinical and electrodiagnostic examination demonstrated mild progression of the disease.
Hund
E
E
Department of Neurology, University of Heidelberg, Germany.
Heckl
R
R
Goebel
H H
HH
Meinck
H M
HM
D000368:Aged; D006801:Humans; D002479:Inclusion Bodies; D008297:Male; D009132:Muscles / Q000648:ultrastructure; D009220:Myositis / Q000473:pathology*; D010291:Paresis / Q000473:pathology*; D013131:Spine