title: Short latency median nerve somatosensory evoked potential (SEP): increase in stimulation frequency from 3 to 30 Hz.
abstract: Somatosensory evoked potentials were obtained by electrical stimulation of the median nerve in 10 normal subjects at 3 and 30 Hz. At the higher rate of stimulation, a reduction was observed in amplitudes and prolongation of latencies of the N9, N/P13 and N20 components as well as increase of the interpeak latency N9-N/P13. A significant increase between the onsets of the N11 and N20 components was also seen; however, no significant increase of the N/P13-N20 interpeak latency was observed. Analysis suggested that an important reason for this last finding was related to the fact that in some cases different fast frequency components (FFC) determined the N20 peak in the different situations. It was further observed that, in those cases in which at least 3 peaks in the fast frequency components were detected (7/10), a significantly different increase in latency between the first and the third peaks was noted. A possible thalamo-cortical generation of the FFC is discussed.
authors.affiliation: Clinical Neurophysiology Laboratory, Escola Paulista de Medicina, São Paulo, Brazil.
authors.forename: G M
authors.initials: GM
authors.lastname: Manzano
authors.forename: J M
authors.initials: JM
authors.lastname: De Navarro
authors.forename: J A
authors.initials: JA
authors.lastname: Nóbrega
authors.forename: N F
authors.initials: NF
authors.lastname: Novo
authors.forename: Y
authors.initials: Y
authors.lastname: Juliano
mesh_terms: D000293:Adolescent; D000328:Adult; D004558:Electric Stimulation; D004569:Electroencephalography; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology