title: Cervical intraepithelial neoplasia (CIN): management by a general (non-oncological) gynaecological unit.
abstract: The purpose of this study is to assess how well Cervical Intraephithelial Neoplasia (CIN) was managed by a general gynaecological unit. Treatment consisted of laser ablation, conization (laser, knife, loop diathermy) and hysterectomy. Recurrence occurred in 8 (18.2%) out of 44 conizations and 2 (25.0%) out of 8 ablative procedures. While the cure rate after the first treatment was 81.1%, after subsequent treatment it became 96.2%. This study showed that it was possible for a general gynaecological unit to cure patients of their disease. The Pap smear tests were not very accurate--the sensitivity and specificity were 75.5% and 50.0% respectively while the positive predictive value and negative predictive value were 94.9% and 14.3% respectively. Similarly, colposcopically directed punch biopsy was also found to be misleading.
authors.affiliation: Department of Reproductive Medicine, Kandang Kerbau Hospital, Singapore.
authors.forename: M S
authors.initials: MS
authors.lastname: Goon
authors.forename: B L
authors.initials: BL
authors.lastname: Tay
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D006176:Gynecology; D006757:Hospital Units; D006801:Humans; D007044:Hysterectomy; D053685:Laser Therapy; D008875:Middle Aged; D065006:Papanicolaou Test; D012008:Recurrence; D012680:Sensitivity and Specificity; D013997:Time Factors; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000473:pathology / Q000601:surgery*