Behavior of beta 2-microglobulin (B2-m) serum levels in uremic patients.
This study was performed in 97 hemodialysis patients (85 on HD and 12 on CAPD) to investigate the possible correlation between B2-m and hemodialysis-related amyloidosis syndromes (HRA-S); differences in B2-m and HRA behavior between patients hemodialysed with cellulose and synthetic membranes were also included in the present study. Data indicate that B2-m levels are not correlated with dialysis length or with the type of membrane used for the dialysis. On the contrary, in 16 patients with the Carpal Tunnel Syndrome, a significant correlation was found between the CTS, the dialysis length and the type of membrane (greater incidence with cellulosic membranes).
Mioli
V A
VA
Nephrological and Dialysis Department, Umberto 1st University Hospital, Torrette di Ancona, Italy.
Balestra
E
E
Bibiano
L
L
Dellabella
S
S
Fanciulli
E
E
Gaffi
G
G
Perilli
A
A
Petroselli
F
F
Ricciatti
A M
AM
Carletti
P
P
D000328:Adult; D000368:Aged; D000686:Amyloidosis / Q000097:blood / Q000209:etiology*; D001798:Blood Proteins / Q000378:metabolism; D002349:Carpal Tunnel Syndrome / Q000097:blood / Q000209:etiology; D002482:Cellulose / Q000737:chemistry; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D006435:Renal Dialysis / Q000009:adverse effects*; D014511:Uremia / Q000097:blood* / Q000628:therapy; D001613:beta 2-Microglobulin / Q000378:metabolism*
D001798:Blood Proteins; D008567:Membranes, Artificial; D001613:beta 2-Microglobulin; D002482:Cellulose