Genotoxic effects of deltamethrin in the mouse bone marrow micronucleus assay.
The genotoxicity of deltamethrin was studied in Swiss albino male mice (five animals/group) using the bone marrow micronucleus assay. Deltamethrin (two i.p. injections, 30 h and 6 h before sample collection) was found to induce micronuclei at 162.5 and 300.0 mg/kg body weight. A lower dose (32.5 mg/kg body weight) failed to induce a significant increase in micronuclei over the control level.
Gandhi
G
G
Department of Human Genetics, Guru Nanak Dev University, Amritsar, India.
Chowdhury
J B
JB
Sareen
P K
PK
Dhillon
V P
VP
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D051379:Mice; D015162:Micronucleus Tests; D009570:Nitriles; D011722:Pyrethrins / Q000633:toxicity*
D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin