Eleven novel mutations in the NF2 tumour suppressor gene.
Eleven novel mutations were identified in the NF2 tumour suppressor gene in a panel of British NF2 patients. Screening was performed using a combination of heteroduplex and single-strand conformation polymorphism analysis on polymerase chain reaction amplified material.
Bourn
D
D
Department of Human Genetics, University of Newcastle upon Tyne, UK.
Evans
G
G
Mason
S
S
Tekes
S
S
Trueman
L
L
Strachan
T
T
D001483:Base Sequence; D004247:DNA / Q000032:analysis / Q000737:chemistry; D016515:Genes, Neurofibromatosis 2 / Q000235:genetics*; D018095:Germ-Line Mutation; D006801:Humans; D008969:Molecular Sequence Data; D016518:Neurofibromatosis 2 / Q000235:genetics*; D009692:Nucleic Acid Heteroduplexes / Q000032:analysis; D016133:Polymerase Chain Reaction; D018807:Polymorphism, Single-Stranded Conformational; D012091:Repetitive Sequences, Nucleic Acid
D009692:Nucleic Acid Heteroduplexes; D004247:DNA