Antibacterial trichorabdal diterpenes from Rabdosia trichocarpa.
Four antibacterial diterpenes, trichorabdals A, B, C and H were isolated from the leaves of Rabdosia trichocarpa and the relationship between their conformations analysed by spectroscopic and computational methods. Their antibacterial activity is discussed.
Osawa
K
K
Department of Basic Research, Lotte Central Laboratory Co., Ltd., Saitama, Japan.
Yasuda
H
H
Maruyama
T
T
Morita
H
H
Takeya
K
K
Itokawa
H
H
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D003460:Crystallization; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D009904:Optical Rotation; D018515:Plant Leaves / Q000737:chemistry; D010944:Plants / Q000737:chemistry*; D013053:Spectrophotometry
D000900:Anti-Bacterial Agents; D004224:Diterpenes; C090071:trichorabdal H; C090068:trichorabdal B; C090066:trichorabdal A; C090069:trichorabdal C