Enzyme-labelled oligonucleotides for the detection of alpha 1-antitrypsin deficiency: optimization of enzyme activity for single point mutation detection.
Cook
D
D
Department of Clinical Chemistry, University Hospital, Queen's Medical Centre, Nottingham, UK.
Morgan
K
K
Kalsheker
N
N
D000469:Alkaline Phosphatase; D000483:Alleles; D001483:Base Sequence; D002384:Catalysis; D003124:Colorimetry; D006801:Humans; D008163:Luminescent Measurements; D008969:Molecular Sequence Data; D009841:Oligonucleotides; D017354:Point Mutation; D000515:alpha 1-Antitrypsin / Q000235:genetics; D019896:alpha 1-Antitrypsin Deficiency
D009841:Oligonucleotides; D000515:alpha 1-Antitrypsin; D000469:Alkaline Phosphatase