Gene probe assays and their detection.
The detection of specific nucleic acid sequences plays a major role in modern biology and in medicine it is involved in analyzing basic genome structure and function, identifying mutated oncogenes, infectious or genetic diseases, typing tissues before transplantation, and comparing DNA sequences in forensic situations. This review explores recent developments relating to gene probe assays and their reporter systems.
Nickerson
D A
DA
Department of Molecular Biotechnology, University of Washington School of Medicine, Seattle 98195.
D006801:Humans; D015341:Nucleic Acid Probes / Q000032:analysis; D012680:Sensitivity and Specificity
D015341:Nucleic Acid Probes