Scope and limitations of gene therapy.
Although there are still many technical difficulties to be overcome, recent advances in the molecular and cellular biology of gene transfer have made it likely that gene therapy will soon start to play an increasing role in clinical practice. It will not be restricted to the management of monogenic disorders, but will have applications across many other fields of medicine, particularly the treatment of cancer and infectious disease.
Weatherall
D J
DJ
Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, UK.
D004992:Ethics, Medical; D005786:Gene Expression Regulation; D018014:Gene Transfer Techniques; D030342:Genetic Diseases, Inborn / Q000628:therapy; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000628:therapy; D012190:Retroviridae / Q000235:genetics; D014777:Virus Diseases / Q000628:therapy