title: Phenotype analysis of mononuclear cells in endomyocardial biopsy specimens from patients with viral myocarditis and dilated cardiomyopathy.
abstract: This study investigated the distribution and phenotype of mononuclear cells in endomyocardial biopsy (EMB) specimens from patients with viral myocarditis (VMC, 25 cases) and dilated cardiomyopathy (DCM, 10 cases). T lymphocytes, including Th/i cells in VMC and Tc/s cells in DCM, predominated in the infiltrating mononuclear cells in these specimens. The morphological relationship between infiltration of T lymphocytes and pathological changes of myocardia was also observed and neither macrophages nor B lymphocytes were found.
authors.affiliation: Department of Internal Medicine, Tongji Hospital, Tongji Medical University, Wuhan.
authors.forename: W
authors.initials: W
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Yu
authors.forename: D W
authors.initials: DW
authors.lastname: Wang
mesh_terms: D000328:Adult; D001706:Biopsy; D002311:Cardiomyopathy, Dilated / Q000235:genetics* / Q000473:pathology; D004699:Endocardium / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000235:genetics* / Q000473:pathology / Q000821:virology; D009206:Myocardium / Q000473:pathology*; D010641:Phenotype; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D014777:Virus Diseases / Q000235:genetics / Q000473:pathology