title: Video-assisted thoracoscopic pleurectomy in the management of malignant pleural effusion.
abstract: OBJECTIVE
  To evaluate the outcome of pleurectomy using video-assisted thoracic surgery (VATS) for pleurodesis in patients with malignant pleural effusion.
  
  
  METHODS
  Cohort prospective study. Follow-up of patients from referral for thoracoscopy to death.
  
  
  METHODS
  Regional Cardiothoracic Surgical Centre.
  
  
  METHODS
  Nineteen patients (median age 63 years, range 51 to 84 years) with malignant pleural effusion, secondary to mesothelioma in 13 and metastatic adenocarcinoma in 6.
  
  
  METHODS
  Video-assisted parietal pleurectomy.
  
  
  RESULTS
  Median operating time was 35 min (range 15 to 60 min). The median fall in hemoglobin concentration in the first 24 h postsurgery was 1.1 g/dL (0.3-2.5 g/dL). The median postoperative morphine requirement was 1.25 mg/h (0-6.2 mg/h) in the first 12 h postoperatively. All patients were successfully extubated in the operating room, without the need for reventilation, and all patients were successfully discharged from the hospital with a median postoperative stay of 5 days (range 2 to 20 days). At current median follow-up of 12 months (range 4 to 17 mon) 6 patients died of their underlying disease. In the remaining 13 patients, two have developed recurrent effusions.
  
  
  CONCLUSIONS
  Using VATS to perform parietal pleurectomy is a safe, effective method of obtaining palliative pleurodesis in patients with malignant effusions.
authors.affiliation: Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle Upon Tyne, England.
authors.forename: D A
authors.initials: DA
authors.lastname: Waller
authors.forename: G N
authors.initials: GN
authors.lastname: Morritt
authors.forename: J
authors.initials: J
authors.lastname: Forty
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010994:Pleura / Q000601:surgery*; D016066:Pleural Effusion, Malignant / Q000601:surgery*; D011446:Prospective Studies; D013514:Surgical Procedures, Operative / Q000379:methods; D013690:Television; D020708:Thoracoscopes; D016896:Treatment Outcome; D014741:Video Recording