title: Isolation and structural elucidation of pentacyclic triterpenoids from Maprounea africana.
abstract: Pentacyclic triterpenoids based on the taraxer-14-ene skeleton with a C-28 attached carboxylic acid group have been isolated from the roots of Maprounea africana. These compounds were identified as 1 beta,2 alpha-dihydroxyaleuritolic acid 2,3-bis-p-hydroxybenzoate [1], 2 alpha-hydroxyaleuritolic acid 3-p-hydroxybenzoate [2], 2 alpha-hydroxyaleuritolic acid 2,3-bis-p-hydroxybenzoate [4], aleuritolic acid 3-p-hydroxybenzoate [5], aleuritolic acid [6], and aleuritolic acid 3-acetate [7]. Compounds 1 and 2 are new triterpene esters. Compound 3 was previously reported as 7 beta-hydroxymaprounic acid 3-p-hydroxybenzoate [13]. However, based on detailed nmr studies, its structure has been revised.
authors.affiliation: Chemistry and Life Sciences Group, Research Triangle Institute, Research Triangle Park, North Carolina 27709.
authors.forename: S K
authors.initials: SK
authors.lastname: Chaudhuri
authors.forename: F
authors.initials: F
authors.lastname: Fullas
authors.forename: D M
authors.initials: DM
authors.lastname: Brown
authors.forename: M C
authors.initials: MC
authors.lastname: Wani
authors.forename: M E
authors.initials: ME
authors.lastname: Wall
authors.forename: L
authors.initials: L
authors.lastname: Cai
authors.forename: W
authors.initials: W
authors.lastname: Mar
authors.forename: S K
authors.initials: SK
authors.lastname: Lee
authors.forename: Y
authors.initials: Y
authors.lastname: Luo
authors.forename: K
authors.initials: K
authors.lastname: Zaw
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010947:Plants, Toxic / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D014315:Triterpenes