Congenital limb reduction defects: report of two cases.
We describe two Malay male term neonates with congenital limb reduction defects. The first neonate had hypodactyly of limbs associated with micrognathia, microstomia, glossopalatine ankylosis and congenital mitral stenosis. He developed gram-negative septicaemia and died on day 14 of life. The second neonate had tetraperomelia without any other associated congenital abnormality. He developed staphylococcal skin infection which was treated conservatively. Very few cases of congenital limb reduction defects have been reported in the Asian population and we are not aware of any other reports describing Malay infants with the congenital abnormalities described in this report.
Malik
A S
AS
Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kelantan.
Ram
S P
SP
Seng
Q B
QB
Noor
A R
AR
D000015:Abnormalities, Multiple / Q000208:ethnology*; D006801:Humans; D007231:Infant, Newborn; D017880:Limb Deformities, Congenital; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D008946:Mitral Valve Stenosis / Q000151:congenital; D013577:Syndrome; D014059:Tongue / Q000002:abnormalities