title: Pleomorphic rhabdomyosarcoma of the heart metastatic to bone. Report of a case with fine needle aspiration biopsy findings.
abstract: Pleomorphic rhabdomyosarcoma is an extremely rare and highly malignant neoplasm. We report an unusual case of a 14-year-old boy with skeletal metastases from a primary cardiac tumor. Fine needle aspiration biopsy of a lytic lesion in the right iliac wing showed a pleomorphic population of clusters and single cells with hyperchromatic nuclei; granular, pink cytoplasm; and isolated, large cells with whiplike or globoid cytoplasmic processes and occasional striations. Histologic, ultrastructural and radiologic features are also presented.
authors.affiliation: Department of Laboratories, North Shore University Hospital-Cornell University Medical College, Manhasset, New York 11030, USA.
authors.forename: S Z
authors.initials: SZ
authors.lastname: Ali
authors.forename: T F
authors.initials: TF
authors.lastname: Smilari
authors.forename: S
authors.initials: S
authors.lastname: Teichberg
authors.forename: S I
authors.initials: SI
authors.lastname: Hajdu
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D002454:Cell Differentiation; D003937:Diagnosis, Differential; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D012208:Rhabdomyosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D014057:Tomography, X-Ray Computed