title: Nuclear disintegration in chicken peritoneal macrophages exposed to fumonisin B1 from Indian maize.
abstract: The effects of fumonisin B1 (FB1) on the morphology of chicken peritoneal macrophages were studied. It was found that FB1-exposure caused nuclear disintegrations in peritoneal macrophages. The number of macrophages experiencing nuclear disintegration increased with the rise in the dose of FB1 from 6 to 18 micrograms ml-1. The finding implies that dietary intake of FB1 may damage the macrophages in consumers rendering the latter susceptible to infection.
authors.affiliation: Department of Food Technology and Biochemical Engineering, Jadavpur University, Calcutta, India.
authors.forename: D
authors.initials: D
authors.lastname: Chatterjee
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherjee
authors.forename: A
authors.initials: A
authors.lastname: Dey
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects*; D002645:Chickens; D005260:Female; D037341:Fumonisins; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000648:ultrastructure*; D009183:Mycotoxins / Q000494:pharmacology*; D003313:Zea mays / Q000382:microbiology
chemical_list: D037341:Fumonisins; D009183:Mycotoxins; C056933:fumonisin B1