Improvement of the DNA repair capacity of human fibroblasts by autolysates of Lactobacillus gasseri.
Autolysates of Lactobacillus gasseri were tested for their ability to improve repair capacity in cultured human fibroblasts. In the course of this research on molecular mechanisms of hereditary DNA repair deficiencies and presenility syndromes, a significant and reproducible effect on repair capacity in these cells by an autolysate of the gram-positive bacterium Lactobacillus gasseri was found.
Weirich-Schwaiger
H
H
Institut für Medizinische Biologie und Genetik der Universität Innsbruck, Austria.
Weirich
H G
HG
Kludas
M
M
Hirsch-Kauffmann
M
M
D000293:Adolescent; D000328:Adult; D001329:Autolysis; D002467:Cell Nucleus / Q000737:chemistry / Q000528:radiation effects; D002478:Cells, Cultured; D003057:Cockayne Syndrome / Q000378:metabolism; D004260:DNA Repair; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D006801:Humans; D007778:Lactobacillus / Q000378:metabolism*; D008297:Male; D014466:Ultraviolet Rays