Comparative antilipoperoxidant, antinecrotic and scavenging properties of terpenes and biflavones from Ginkgo and some flavonoids.
Ginkgo biloba extract is known to be efficient in diseases associated with free radical generation. This study compares the in vitro effect of some constituents of Ginkgo against lipid peroxidation and cell necrosis of isolated rat hepatocytes, and against superoxide anion which is generally implicated in cell damages.
Joyeux
M
M
CEREPHA, Metz, France.
Lobstein
A
A
Anton
R
R
Mortier
F
F
D000818:Animals; D002478:Cells, Cultured; D005419:Flavonoids / Q000494:pharmacology* / Q000627:therapeutic use; D005609:Free Radicals; D015227:Lipid Peroxidation / Q000187:drug effects*; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D008297:Male; D009336:Necrosis / Q000188:drug therapy; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013729:Terpenes / Q000494:pharmacology* / Q000627:therapeutic use
D005419:Flavonoids; D005609:Free Radicals; D013729:Terpenes