[Human bone marrow cell culture--a sensitive method for the evaluation of the biocompatibility of materials used in orthopedics].
The objective of the study was to develop a test system to determine the cytotoxicity and biocompatibility of different biomaterials used in orthopedic surgery. This system was based on the use of a human bone marrow cell culture and the purpose was to find a screening method as a alternative to early animal experimental methods. The established human bone marrow cell culture has certain advantages when compared with other cell culture models. The result demonstrated a high conformity with animal experimental results.
Wilke
A
A
Orthopädische Klinik, Philipps-Universität Marburg.
von Hirschheydt
S
S
Orth
J
J
Kienapfel
H
H
Griss
P
P
Franke
R P
RP
D001672:Biocompatible Materials / Q000032:analysis*; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D006801:Humans; D008855:Microscopy, Electron, Scanning; D008856:Microscopy, Fluorescence
D001672:Biocompatible Materials
Die humane Knochenmarkszellkultur--Eine sensitive Methode zur Beurteilung der Biokompatibilität von Materialien, die in der Orthopädie verwendet werden.