title: Benefits and complications of laparoscopic pelvic lymphadenectomy for detection of stage D1 prostate cancer: a multicenter experience.
abstract: One hundred fifty-eight consecutive patients with clinically localized prostate cancer were submitted to staging laparoscopic pelvic lymphadenectomy (LPL) at 5 cooperative centers with one or more of the following conditions which were considered as risk factors for nodal disease: clinical stage C (or T3) disease, serum prostate-specific antigen > 20 ng/ml, Gleason sum > 6. The mean number of lymph nodes removed was 11 (range 2-29). Metastases from prostate cancer were found in 41 patients (25.9%). The proportion of lymph node-positive patients increases significantly with the presence of one, two or three of the conditions considered as risk factors (p < 0.00005). The benefit of LPL is limited to the lymph node-positive patients who can be spared a second operation.
authors.affiliation: Institute of Urology, University of Trieste, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Maffezzini
authors.forename: G
authors.initials: G
authors.lastname: Carmignani
authors.forename: M
authors.initials: M
authors.lastname: Perachino
authors.forename: P
authors.initials: P
authors.lastname: Puppo
authors.forename: F
authors.initials: F
authors.lastname: Montorsi
authors.forename: G
authors.initials: G
authors.lastname: Guazzoni
authors.forename: M
authors.initials: M
authors.lastname: Gallucci
authors.forename: F
authors.initials: F
authors.lastname: Di Silverio
authors.forename: M
authors.initials: M
authors.lastname: Morelli
authors.forename: G
authors.initials: G
authors.lastname: Muto
mesh_terms: D006801:Humans; D007558:Italy; D010535:Laparoscopy / Q000009:adverse effects; D008197:Lymph Node Excision / Q000009:adverse effects / Q000379:methods; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging / Q000009:adverse effects / Q000379:methods; D010388:Pelvis; D011471:Prostatic Neoplasms / Q000473:pathology / Q000601:surgery*; D012307:Risk Factors