Distribution of HLA antigens in Indian Gurkha population.
Fifty unrelated Indian Gurkha of Nepalese origin were studied to analyse the HLA antigen profile and their relation with other populations. Haplotype B35-Cw4 occurred with highest incidence and significant positive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs with the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas. HLA profile of Gurkhas thus may be the result of long-term isolation and genetic drift.
Chaudhuri
T K
TK
Department of Zoology, University of North Bengal, Siliguri.
Mandal
T K
TK
Sen
T K
TK
Taneja
V
V
D006680:HLA Antigens / Q000235:genetics*; D006239:Haplotypes; D007194:India; D015810:Linkage Disequilibrium; D010641:Phenotype
D006680:HLA Antigens