title: [Severe toxic optic neuropathies caused by isoniazid. Apropos of 3 cases].
abstract: Three cases of isoniazid-induced toxic optic neuropathy are reported. These severe forms of the disease lead in all cases to bilateral blindness despite drug withdrawal. The epidemiological, clinical and therapeutic aspects of the disease are discussed. Further emphasis is placed on the importance of systematic screening of patients at risk using regular ophthalmological examinations before and after treatment.
authors.affiliation: Clinique Ophtalmologique B, Hôpital des Spécialités, CHU, Ibn Sina, Rabat, Maroc.
authors.forename: A
authors.initials: A
authors.lastname: Boulanouar
authors.forename: E
authors.initials: E
authors.lastname: Abdallah
authors.forename: M
authors.initials: M
authors.lastname: el Bakkali
authors.forename: F
authors.initials: F
authors.lastname: Benchrifa
authors.forename: A
authors.initials: A
authors.lastname: Berraho-Hamani
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000139:chemically induced*; D012307:Risk Factors
chemical_list: D007538:Isoniazid
vernacular_title: Neuropathies optiques toxiques graves induites par l'isoniazide. A propos de trois cas.