title: Identification of a novel amide peptide, GLTPNMNSLFF-NH2, involved in the control of vas deferens motility in lymnaea stagnalis.
abstract: Peptide messengers are crucial for the execution of male copulatory processes in the snail Lymnaea stagnalis. In this study, we report the purification of a novel peptide from the penis complex of L. stagnalis. This peptide enhances the contraction frequency and contraction amplitude of the vas deferens. Amino acid sequencing and mass spectrometry indicate that the primary structure is GLTPNMNSLFF-NH2. We propose that this amide peptide modulates the transfer rate of semen in the vas deferens.
authors.affiliation: Graduate School Neurosciences Amsterdam, Research Institute Neurosciences, Vrije Universiteit, The Netherlands.
authors.forename: K W
authors.initials: KW
authors.lastname: Li
authors.forename: Z
authors.initials: Z
authors.lastname: el Filali
authors.forename: F A
authors.initials: FA
authors.lastname: Van Golen
authors.forename: W P
authors.initials: WP
authors.lastname: Geraerts
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D008195:Lymnaea / Q000502:physiology*; D008297:Male; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000302:isolation & purification* / Q000378:metabolism; D010455:Peptides / Q000302:isolation & purification* / Q000378:metabolism; D014649:Vas Deferens / Q000502:physiology*
chemical_list: D009479:Neuropeptides; D010455:Peptides; C093545:GLTPNMNSLFFamide