title: Hyperthermia in the treatment of brain metastases from lung cancer. Experience on 17 cases.
abstract: Medium or long-term survival in metastatic "non oat cell" lung tumors is seldom possible only if surgery can eradicate the lesion. Out of 17 patients treated with hyperthermia plus nitrosoureas 16 (94%) responded, with clinical improvement, radiological regression or disease stabilization. The survival time of the improved patients was 12.7 months. Hyperthermia in combination with nitrosoureas seems to allow clinically and radiologically satisfactory responses in lung tumors metastatic to the brain.
authors.affiliation: Service of Oncologic Hyperthermia, Casa di Cura Città di Pavia, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Pontiggia
authors.forename: F
authors.initials: F
authors.lastname: Duppone Curto
authors.forename: G
authors.initials: G
authors.lastname: Rotella
authors.forename: A
authors.initials: A
authors.lastname: Sabato
authors.forename: S
authors.initials: S
authors.lastname: Rizzo
authors.forename: G
authors.initials: G
authors.lastname: Butti
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009607:Nitrosourea Compounds / Q000627:therapeutic use; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D009607:Nitrosourea Compounds