title: Antimicrobial sesquiterpenes from Prostanthera aff. melissifolia and P. rotundifolia.
abstract: Aerial material of Prostanthera aff. melissifolia and P. rotundifolia yielded three sesquiterpenes, two known compounds and a novel sesquiterpene, prostantherol. Prostantherol was identified as (rel)-1a alpha,3a beta,7a alpha,7b alpha-decahydro-4 beta-hydroxy- 1,1,4 alpha,7 alpha-tetramethylcyclopropa[a]-naphthalene on the basis of a comprehensive spectroscopic analysis. All three compounds were investigated for antimicrobial activity against phytopathogens.
authors.affiliation: Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, U.K.
authors.forename: J E
authors.initials: JE
authors.lastname: Dellar
authors.forename: M D
authors.initials: MD
authors.lastname: Cole
authors.forename: A I
authors.initials: AI
authors.lastname: Gray
authors.forename: S
authors.initials: S
authors.lastname: Gibbons
authors.forename: P G
authors.initials: PG
authors.lastname: Waterman
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010944:Plants / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D012717:Sesquiterpenes