Ogilvie's syndrome from disseminated varicella-zoster infection and infarcted celiac ganglia.
We report a patient who had refractory Hodgkin's disease and who received an autologous bone marrow transplantation and 8 months later developed abdominal pain associated with acute colonic dilation. The course of the patient was rapidly fatal due to a lobar pneumonia. Autopsy revealed signs of disseminated herpesvirus infection with marked hemorrhagic infarction of celiac sympathetic ganglia. This finding supports the hypothesis that denervation caused by virus reactivation and secondary hemorrhage is a main mechanism of acute colonic pseudoobstruction.
Nomdedéu
J F
JF
Department of Hematology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Nomdedéu
J
J
Martino
R
R
Bordes
R
R
Portorreal
R
R
Sureda
A
A
Domingo-Albós
A
A
Rutllant
M
M
Soler
J
J
D000328:Adult; D016026:Bone Marrow Transplantation; D003112:Colonic Pseudo-Obstruction / Q000209:etiology* / Q000276:immunology; D005728:Ganglia, Sympathetic / Q000098:blood supply*; D006562:Herpes Zoster / Q000150:complications* / Q000276:immunology; D014645:Herpesvirus 3, Human / Q000302:isolation & purification*; D006689:Hodgkin Disease / Q000276:immunology / Q000628:therapy; D006801:Humans; D016867:Immunocompromised Host; D007238:Infarction / Q000150:complications*; D008297:Male; D014182:Transplantation, Autologous