title: The evaluation of a biexponential model for description of intercompartmental fluid shifts in compressed oedematous tissue.
abstract: A parametric model was fitted to force curve data gained by a non-invasive impression method that measures force and fluid translocation during mechanical compression of the skin. The ability of the model parameters to estimate high- and low-viscosity fluid flow in compressed areas were evaluated in a silicone rubber model and in six patients with chronic pitting oedema. Different softnesses of silicone rubber gave significantly different parameter values. The flow properties of the silicone model could be analysed in detail with the suggested model. Parameter analysis showed a higher fraction of low-viscosity fluid for oedema than for reference sites. The model parameters could be interpreted in softness value according to an international standard for consistency (ISO 2137). The suggested parametric model gave reliable and detailed information about high- and low-viscosity fluid flow and can be used to estimate intercompartmental fluid shifts in oedematous tissue.
authors.affiliation: Department of Biomedical Engineering, University Hospital of Northern Sweden, Umeå.
authors.forename: O A
authors.initials: OA
authors.lastname: Lindahl
mesh_terms: D000368:Aged; D002908:Chronic Disease; D004487:Edema / Q000503:physiopathology*; D005069:Evaluation Studies as Topic; D005260:Female; D018495:Fluid Shifts / Q000502:physiology*; D006801:Humans; D008433:Mathematics; D008875:Middle Aged; D008954:Models, Biological; D012828:Silicones
chemical_list: D012828:Silicones