title: The Microspheres based Detoxification System (MDS). A new extracorporeal blood purification technology based on recirculated microspherical adsorbent particles.
abstract: Plasma sorption processes have so far been performed with filters and appropriate adsorption columns. In this paper, we introduce a newly developed plasma sorption system, which is based on the high adsorption capacity of microspheres in a recirculation system. The technology has been applied successfully in vitro to eliminate endotoxins, low density lipoproteins (LDL) and barbiturates from human plasma.
authors.affiliation: Interdisciplinary Institute of Bioengineering, Science Academy of Lower Austria, Krems.
authors.forename: C
authors.initials: C
authors.lastname: Weber
authors.forename: C
authors.initials: C
authors.lastname: Rajnoch
authors.forename: F
authors.initials: F
authors.lastname: Loth
authors.forename: H
authors.initials: H
authors.lastname: Schima
authors.forename: D
authors.initials: D
authors.lastname: Falkenhagen
mesh_terms: D000818:Animals; D001463:Barbiturates / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D004731:Endotoxins / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification; D008863:Microspheres; D011312:Pressure; D012015:Reference Standards; D016060:Sorption Detoxification / Q000592:standards* / Q000639:trends; D013552:Swine
chemical_list: D001463:Barbiturates; D004731:Endotoxins; D008077:Lipoproteins, LDL