title: Isolation of antifungal and larvicidal constituents of Diplolophium buchanani by centrifugal partition chromatography.
abstract: Three phenylpropanoids, myristicin [1], elemicin [2], and trans-isoelemicin [3], together with two furanocoumarins, oxypeucedanin [4] and oxypeucedanin hydrate [5], have been isolated from the leaves of Diplolophium buchanani by a separation strategy involving the almost exclusive use of centrifugal partition chromatography. All five compounds were antifungal in a tlc bioautography test using Cladosporium cucumerinum. Compounds 1-4 exhibited larvicidal activity against Aedes aegypti.
authors.affiliation: Institut de Pharmacognoise et Phytochimie, Université de Lausanne, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Marston
authors.forename: K
authors.initials: K
authors.lastname: Hostettmann
authors.forename: J D
authors.initials: JD
authors.lastname: Msonthi
mesh_terms: D000330:Aedes; D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002845:Chromatography / Q000379:methods; D002850:Chromatography, Gel; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification*; D007814:Larva; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry*
chemical_list: D000935:Antifungal Agents; D007306:Insecticides