Multiple metastases of mammary carcinoma cell lines isolated from feral mouse.
Two established cell lines (JYG-A and B) isolated from mammary carcinoma tissues of M. m. musculus Sub-Jyg (a chinese wild mouse) showed multiple metastasis in the lung (100%), liver (40-60%), kidney (40-80%), lymph node (20-60%) and other organs of the nude mice inoculated with these cells subcutaneously or intravenously. In addition, 100% brain metastasis or infiltration was observed only when inoculated with JYG-B cells intravenously.
Hiroishi
S
S
Faculty of Biotechnology, Fukui Prefectural University, Obama City, Japan.
Morimoto
J
J
Taniguchi
Y
Y
Mori
H
H
D000818:Animals; D005260:Female; D007680:Kidney Neoplasms / Q000556:secondary; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008325:Mammary Neoplasms, Experimental / Q000473:pathology*; D008324:Mammary Tumor Virus, Mouse; D051379:Mice; D008807:Mice, Inbred BALB C; D008815:Mice, Inbred Strains; D008819:Mice, Nude; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation