title: Colonic dilatation due to dialysis-related amyloidosis.
abstract: A 66-year-old woman with chronic renal failure who had undergone hemodialysis for 15 years developed severe dilatation of the ascending and transverse colon. She had received right carpal tunnel release 5 years before this episode. The follow-up study of upper gastrointestinal series disclosed marked dilatation of the ascending and transverse colon with the retention of gastrografin persisted for 5 days, whereas colonic fiberscope showed no obstructive lesion. Pathologic study of biopsy specimens obtained from the colon demonstrated amyloid deposition. Avidin-biotin peroxidase complex method showed that these deposits strongly reacted with the antibody to human beta 2-microglobulin, but did not react with AA, lambda, and kappa antibodies. This case suggests that dialysis-related amyloidosis can cause intestinal pseudo-obstruction.
authors.affiliation: Shinpukai Maruyama Hospital, Hamamatsu, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Ikegaya
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: A
authors.initials: A
authors.lastname: Hishida
authors.forename: E
authors.initials: E
authors.lastname: Kaneko
authors.forename: M
authors.initials: M
authors.lastname: Furuhashi
authors.forename: Y
authors.initials: Y
authors.lastname: Maruyama
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications / Q000209:etiology*; D002349:Carpal Tunnel Syndrome / Q000209:etiology; D003108:Colonic Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology; D005260:Female; D006801:Humans; D011859:Radiography; D006435:Renal Dialysis / Q000009:adverse effects*