title: [Antimutagenic properties of Angelica archangelica L].
abstract: The antimutagenic activity of Angelica archangelica L. aqueous and alcohol extracts of thio-TEPA against mutagenicity was examined by the micronucleus test in murine bone marrow cells. The reduction of Thio-TEPA's mutagenic activity was more profound when the extracts were injected 2 hours before thio-TEPA treatment, as seen during simultaneous treatment. The observed reduction of micronuclear frequencies was as high as 77%.
authors.forename: R A
authors.initials: RA
authors.lastname: Salikhova
authors.forename: G G
authors.initials: GG
authors.lastname: Poroshenko
mesh_terms: D000818:Animals; D016587:Antimutagenic Agents; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D051379:Mice; D015162:Micronucleus Tests; D016296:Mutagenesis / Q000187:drug effects; D010946:Plants, Medicinal; D013852:Thiotepa / Q000633:toxicity
chemical_list: D016587:Antimutagenic Agents; D013852:Thiotepa
vernacular_title: Antimutagennye svoĭstva dudnika lekarstvennogo.