title: The effect of osteoporosis on the mechanical properties of bone structures.
abstract: Since experimental data on the mode of failure of the lumbar vertebral body and the femoral neck scarce, a model predicting their fracture mechanisms under a representative loading is needed. This model should be ask to describe the inference of osteoporosis on the mechanical strength, and should use BMC-measurement date as an input. A simple mechanical model for both structures, composed of a thin-walled cylindrical cortual shell, filled with a trabecular bone core is used. We find that the BMC evaluated as the mineral content in a 1 cm thick section (expressed in g/cm) is a good predictor for the strength of the vertebral body, while for the femoral neck, additional information on the cortical wall thickness is needed.
authors.affiliation: Department of Mechanical Engineering, K.U.-Leuven, Celestijnenlaan 200A, Heverlee, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Van Audekercke
authors.forename: G
authors.initials: G
authors.lastname: Van der Perre
mesh_terms: D015502:Absorptiometry, Photon; D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density; D005272:Femur Neck / Q000503:physiopathology*; D006801:Humans; D008159:Lumbar Vertebrae / Q000503:physiopathology*; D008954:Models, Biological; D010024:Osteoporosis / Q000503:physiopathology*; D013314:Stress, Mechanical