Increases in synaptic activation of calcium current as a mechanism for generation of ethanol withdrawal seizures.
Whittington
M A
MA
Dept of Pharmacology, University of Bristol Medical School, U.K.
Lambert
J D
JD
Little
H J
HJ
D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology; D015220:Calcium Channels / Q000187:drug effects / Q000378:metabolism*; D004095:Dihydropyridines / Q000378:metabolism / Q000494:pharmacology; D000431:Ethanol / Q000633:toxicity*; D006624:Hippocampus / Q000187:drug effects / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D017966:Pyramidal Cells / Q000187:drug effects / Q000378:metabolism; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects / Q000378:metabolism; D013375:Substance Withdrawal Syndrome / Q000378:metabolism*; D013569:Synapses / Q000187:drug effects / Q000378:metabolism*; D009435:Synaptic Transmission / Q000187:drug effects
D002121:Calcium Channel Blockers; D015220:Calcium Channels; D004095:Dihydropyridines; D016194:Receptors, N-Methyl-D-Aspartate; D000431:Ethanol