title: Steroid injection versus conservative treatment of anisometropia amblyopia in juvenile adnexal hemangioma.
abstract: Because of serious side effects, the indications for intralesional steroid injection of adnexal hemangiomas are unclear. Of 23 children with such lesions who were examined over a period of 9 years, 9 had no evidence of amblyopia and needed no intervention. Five required steroids intralesionally and/or systemically because of threatened occlusion of the pupillary axis. The remaining 9 were considered at risk of anisometropic amblyopia because of induced astigmatism: 5 received injections and 4 were treated with glasses and/or patching alone. The visual, refractive, and cosmetic results of the injected and conservatively managed anisometropes were similar. We recommend that steroid injection be reserved for patients with threatened occlusion of the visual axis and for those with severe astigmatism or amblyopia refractory to conservative management.
authors.affiliation: Lion's Eye Institute, Albany Medical College, NY, USA.
authors.forename: M V
authors.initials: MV
authors.lastname: Motwani
authors.forename: J W
authors.initials: JW
authors.lastname: Simon
authors.forename: J D
authors.initials: JD
authors.lastname: Pickering
authors.forename: R A
authors.initials: RA
authors.lastname: Catalano
authors.forename: P L
authors.initials: PL
authors.lastname: Jenkins
mesh_terms: D000550:Amblyopia / Q000209:etiology / Q000628:therapy*; D015858:Anisometropia / Q000209:etiology / Q000628:therapy*; D001623:Betamethasone / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005139:Eyeglasses; D005142:Eyelid Neoplasms / Q000150:complications / Q000188:drug therapy*; D018324:Hemangioma, Capillary / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional; D012029:Refraction, Ocular; D012683:Sensory Deprivation; D014221:Triamcinolone / Q000627:therapeutic use*; D014792:Visual Acuity
chemical_list: D014221:Triamcinolone; D001623:Betamethasone