Successful treatment of epidermolysis bullosa acquisita using intravenous immunoglobulins.
We report a 55-year-old man with severe inflammatory epidermolysis bullosa acquisita. The skin lesions did not respond to various immunosuppressive treatments. The combined administration of prednisone, azathioprine, dapsone and colchicine resulted only in a transient and incomplete resolution of the lesions. The bullae and increased skin fragility were successfully controlled by the addition of high-dose intravenous immunoglobulin therapy.
Mohr
C
C
Department of Dermatology, Westfälische-Wilhelms-Universität, Münster, Germany.
Sunderkötter
C
C
Hildebrand
A
A
Biel
K
K
Rütter
A
A
Rütter
G H
GH
Luger
T A
TA
Kolde
G
G
D001379:Azathioprine / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D016107:Epidermolysis Bullosa Acquisita / Q000628:therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use
D016756:Immunoglobulins, Intravenous; D003622:Dapsone; D001379:Azathioprine; D003078:Colchicine; D011241:Prednisone