title: Successful term pregnancy after Mustard operation for transposition of the great arteries.
abstract: Transposition of the great arteries is a complex cardiac malformation with poor prognosis without surgical correction. Since the introduction of surgical procedures such as the intra-auricular reorientation of the venous return (Mustard procedure), an increasing number of patients may reach adulthood and experience pregnancy. Because long-term complications after the Mustard operation include systemic heart failure, arrhythmias, venous return stenosis and pulmonary edema, hemodynamic changes during pregnancy and delivery may potentially engender life-threatening complications in these patients. We report the case of a 24-year-old primigravida who underwent a Mustard procedure at the age of 2 years for transposition of the great vessels, and who carried out a full-term pregnancy. The pregnancy was uneventful until the 34th week, when the woman developed signs of moderate right ventricular failure and frequent episodes of accelerated junctional rhythm. Digitalisation improved symptoms and elicited return to normal sinus rhythm. The patient delivered at term by elective cesarean section, under close hemodynamic monitoring.
authors.affiliation: Department of Obstetrics and Gynecology, Hôpital Cantonal Universitaire, Geneve, Switzerland.
authors.forename: M P
authors.initials: MP
authors.lastname: Rousseil
authors.forename: O
authors.initials: O
authors.lastname: Irion
authors.forename: F
authors.initials: F
authors.lastname: Béguin
authors.forename: O
authors.initials: O
authors.lastname: Jaques
authors.forename: R
authors.initials: R
authors.lastname: Adamec
authors.forename: R
authors.initials: R
authors.lastname: Lerch
authors.forename: B
authors.initials: B
authors.lastname: Friedli
authors.forename: K
authors.initials: K
authors.lastname: Rifat
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac; D002585:Cesarean Section; D005260:Female; D006439:Hemodynamics; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D014188:Transposition of Great Vessels / Q000503:physiopathology* / Q000601:surgery*; D014656:Vascular Surgical Procedures / Q000379:methods; D018497:Ventricular Dysfunction, Right