title: Language-activated single-photon emission tomography imaging in the evaluation of language lateralization--evidence from a case of crossed aphasia: case report.
abstract: We report a right-handed patient who developed a nonfluent aphasia after surgery for a right parietal arteriovenous malformation. Resting brain single-photon emission tomography displayed decreased regional cerebral blood flow only in the right hemisphere, with spared regional cerebral blood flow in the left hemisphere. Single-photon emission tomography performed after a language activation task (Boston Naming Task) showed a consistent area of increased regional cerebral blood flow in the right inferior and posterior frontal lobe, supporting a right hemisphere dominance for language. These results suggest a potential role for this noninvasive study in the evaluation of language lateralization.
authors.affiliation: Department of Neurosurgery, University of Illinois at Chicago.
authors.forename: E
authors.initials: E
authors.lastname: Gomez-Tortosa
authors.forename: E M
authors.initials: EM
authors.lastname: Martin
authors.forename: J J
authors.initials: JJ
authors.lastname: Sychra
authors.forename: M
authors.initials: M
authors.lastname: Dujovny
mesh_terms: D000328:Adult; D000849:Anomia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001039:Aphasia, Broca / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000098:blood supply; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000000981:diagnostic imaging / Q000601:surgery*; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000000981:diagnostic imaging / Q000601:surgery; D011183:Postoperative Complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012039:Regional Blood Flow / Q000502:physiology; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014705:Verbal Behavior / Q000502:physiology