title: Bioactive terpenoids from Octocorallia, I. Bioactive diterpenoids: litophynols A and B from the mucus of the soft coral Litophyton sp.
abstract: Two new eunicellin-type diterpenoids, litophynols A [1] and B [2], and the known diterpenoids litophynins E [3], H [11], and I monoacetate [12], were isolated from the mucus secreted by the soft coral Litophyton sp. Their structures have been elucidated on the basis of spectral and single crystal X-ray analyses. These compounds have hemolytic activity.
authors.affiliation: Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyamoto
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: N
authors.initials: N
authors.lastname: Ikeda
authors.forename: T
authors.initials: T
authors.lastname: Komori
authors.forename: R
authors.initials: R
authors.lastname: Higuchi
mesh_terms: D000818:Animals; D003063:Cnidaria / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D006461:Hemolysis / Q000187:drug effects*; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009093:Mucus / Q000737:chemistry; D009990:Oryzias; D011817:Rabbits
chemical_list: D004224:Diterpenes; C091075:litophynol A; C091076:litophynol B