Cytogenetics of the tissue involved in neural tube defects.
Cytogenetic techniques were used to study the tissue involved in neural tube defects. Eighteen patients have been evaluated and no specific alterations have been detected. We conclude that, whatever are the mechanisms that lead to neural tube defect, their origins must be searched for at the molecular level.
Haupt
R
R
Department of Hematology/Oncology, G. Gaslini, Children's Hospital, Genoa, Italy.
Byrne
J
J
Defferrari
R
R
Cama
A
A
Levato
L
L
Lavia
N
N
Vigliarolo
M A
MA
Capra
V
V
Andreussi
L
L
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D002882:Chromosomes, Human, Pair 13; D002883:Chromosomes, Human, Pair 14; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009417:Nerve Tissue / Q000648:ultrastructure*; D009432:Neural Crest / Q000473:pathology; D009436:Neural Tube Defects / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic