title: [Results of neutron therapy in recurrent malignant salivary gland tumors in the head and neck area].
abstract: OBJECTIVE
  The records of 33 patients of recurrent salivary gland tumors of the head and neck regions were analysed.
  
  
  METHODS
  33 patients with recurrent salivary gland tumors were treated with fast neutrons of a 14 MeV DT generator. All patients had been operated several times. 10 patients had been irradiated before with photons or electrons. 24 patients had macroscopic tumor. In many cases advanced tumors were treated.
  
  
  RESULTS
  The median follow-up of our patients is 33 months. 6 patients are still alive without disease. 5 patients are alive with local recurrence or tumor progression. The calculated survival rate for all patients is 45% at 5 years. The calculated control rate for all patients is 43% at 5 years. Most of the late side effects according to the RTOG/EORTC-score were moderate. Only in one case severe late side effects could be observed.
  
  
  CONCLUSIONS
  According to the literature advanced recurrences of salivary gland tumors should be treated with fast neutrons.
authors.affiliation: Abteilung für Strahlentherapie, Universitätskrankenhaus Hamburg-Eppendorf.
authors.forename: A
authors.initials: A
authors.lastname: Krüll
authors.forename: R
authors.initials: R
authors.lastname: Schwarz
authors.forename: D
authors.initials: D
authors.lastname: Heyer
authors.forename: H
authors.initials: H
authors.lastname: Timm
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018267:Carcinoma, Acinar Cell / Q000532:radiotherapy*; D003528:Carcinoma, Adenoid Cystic / Q000532:radiotherapy*; D018277:Carcinoma, Mucoepidermoid / Q000532:radiotherapy*; D005214:Fast Neutrons / Q000627:therapeutic use*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000532:radiotherapy; D009364:Neoplasm Recurrence, Local; D010307:Parotid Neoplasms / Q000532:radiotherapy; D011379:Prognosis; D011879:Radiotherapy Dosage; D012468:Salivary Gland Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D013365:Submandibular Gland Neoplasms / Q000532:radiotherapy; D016019:Survival Analysis; D013997:Time Factors
vernacular_title: Ergebnisse der Neutronentherapie bei rezidivierenden malignen Speicheldrüsentumoren im Kopf-Hals-Bereich.