Adie's tonic pupil secondary to migraine.
A 46-year-old woman observed transient unilateral mydriasis during a classic migraine attack. One week later she experienced a similar episode after which anisocoria was persistent. Subsequent examination showed the clinical and pharmacologic features of a postganglionic parasympathetic paresis (Adie's tonic pupil). This case confirms the hypothesis that transient mydriasis accompanying migraine is due to interruption of parasympathetic innervation rather than sympathetic overactivity.
Purvin
V A
VA
Midwest Eye Institute, Methodist Hospital of Indiana, Indianapolis 46202, USA.
D000270:Adie Syndrome / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications* / Q000503:physiopathology; D015878:Mydriasis / Q000209:etiology / Q000503:physiopathology; D010275:Parasympathetic Nervous System / Q000502:physiology; D011680:Pupil