Sepsis and septic shock. II. Treatment.
Mortality from septic shock is considerable despite the advantages of cardiovascular support and antibiotic therapy. This article reviews current therapy of septic shock including immunotherapy and further possibilities of septic shock treatment. The role of cytokines, their inhibitors and antibodies to endotoxin is mentioned. Although these treatments hold much promise for the future, careful evaluation of both the benefits and complications of therapy is needed before widespread clinical use can be recommended.
Mayer
J
J
Department of Internal Medicine, Masaryk University Hospital, Brno Bohunice, Czech Republic.
Hajek
R
R
Vorlicek
J
J
Tomiska
M
M
D002986:Clinical Trials as Topic; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000502:physiology; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D007167:Immunotherapy; D018805:Sepsis / Q000628:therapy*; D012772:Shock, Septic / Q000628:therapy*
D016207:Cytokines; D007136:Immunoglobulins; C042866:antilipopolysaccharide antibodies