[Radical or conservative surgery in craniopharyngioma? Importance of individualized treatment!].
In a retrospective study of 36 children aged 3-16 years, undergoing 'radical' surgery for craniopharyngioma, postoperative radiography showed tumour excision to have been complete in 25 cases and partial in 11 cases. The recurrence rate was 40% among those treated with surgery alone (N = 27), whereas there were no recurrences among those given adjunctive radiotherapy (RT) (N = 9). Although surgery in the hypothalamic region carries a high risk of severe lasting sequelae, long-term follow-up (mean duration 15 years) showed no difference in this respect between the RT and non-RT subgroups. Until large, preferably international, prospective studies may resolve the lack of consensus regarding the optimal treatment of craniopharyngioma, the authors advocate a more individualised approach, the choice between different treatment modalities and combinations being based on tumour size, location and structure.
Lannering
B
B
Barnoch ungdomsmedicinska kliniken, Ostra sjukhuset, Göteborg.
Westgren
U
U
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003397:Craniopharyngioma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local; D010347:Patient Care Planning; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D012189:Retrospective Studies
Radikal eller konservativ kirurgi vid kraniofaryngiom? Individualiserad behandling viktig!