title: [Consequences of laser CO2 treatment of cervical intraepithelial neoplasias on the anatomic and functional integrity of the cervix].
abstract: OBJECTIVE
  Retrospective study to analyse objectively the effectiveness and anatomic and functional consequences for the cervix of conservative CO2 laser treatment for cervical intraepithelial neoplasia.
  
  
  METHODS
  Analysis of therapeutic effectiveness and anatomic consequences of 1,114 treated patients followed at our colpolaparotomy surgery clinic for cervical dysplasia since 1987. Evaluation of function consequences by comparison with a group of patients who delivered after laser CO2 therapy for dysplasia (n = 56) and a group of control patients (n = 95) with a similar type of dysplasia after delivery and no treatment. The clinical course of the pregnancy and delivery were compared between the groups in search for risk of prematurity.
  
  
  RESULTS
  Good preservation of cervical anatomy was achieved after a rigorous treatment protocol only applicable with CO2 laser. The preservation of the junctional zone facilitated diagnosis of recurrence. The risk of prematurity was low. Therapy was successful in 93.4% of the cases.
  
  
  CONCLUSIONS
  The choice of conservative therapy is essential, not only when the patient desires a pregnancy but also in others since preserved anatomy facilitates diagnosis of recurrence. This findings implicate the need for an unagressive energy source and also accepting the early diagnosis and treatment.
authors.affiliation: Département de Gynécologie-Obstétrique, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Suisse.
authors.forename: S
authors.initials: S
authors.lastname: Spuhler
authors.forename: E
authors.initials: E
authors.lastname: Outcha Adjahoto
authors.forename: K
authors.initials: K
authors.lastname: Raszka
authors.forename: P
authors.initials: P
authors.lastname: De Grandi
mesh_terms: D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000601:surgery*; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000601:surgery*
vernacular_title: Conséquences du traitement des néoplasies intraépithéliales cervicales par laser CO2 sur l'intégrité anatomique et fonctionnelle du col utérin.