Diagnosis of American trypanosomiasis (Chagas' disease) by the new complement fixation test.
A new immunodiagnostic method of complement fixation was used for serodiagnosis of American trypanosomiasis; 92% sensitivity and 99% specificity were obtained, for an overall accuracy of 97%. This test can be used in field studies, obviating the use of most laboratory equipment and imported reagents; places where economic limitations hinder the use of other immunodiagnostic procedures; and in association with other tests for confirmation of the diagnosis.
Garcia
E
E
National Institute of Neurology and Neurosurgery of Mexico, Mexico City.
Ramirez
L E
LE
Monteon
V
V
Sotelo
J
J
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000953:Antigens, Protozoan; D014355:Chagas Disease / Q000175:diagnosis* / Q000276:immunology; D003168:Complement Fixation Tests / Q000379:methods* / Q000706:statistics & numerical data; D005069:Evaluation Studies as Topic; D006801:Humans; D012680:Sensitivity and Specificity; D014349:Trypanosoma cruzi / Q000276:immunology
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan