title: Thallium-201 uptake in eosinophilic granuloma of the frontal bone: comparison with technetium-99m-MDP imaging.
abstract: An 11-yr-old female presented with a 6-wk history of left upper lid tenderness and left eye lacrimation. Left lateral supraorbital mass and left preauricular lymph node were the only significant physical examination findings. On skull x-ray, a left frontal bone defect was noted. CT and MRI showed a soft-tissue mass in the area of the bone defect. Bone scintigraphy exhibited peripheral uptake within the central photon deficient area. With 201TI SPECT, high uptake was noted on early and delayed images. Diagnosis of eosinophilic granuloma was performed by biopsy. Since thallium uptake was seen in the area where photon deficiency was exhibited by 99mTc-MDP scintigraphy, we speculate that thallium SPECT could detect eosinophilic granuloma when radiographic skeletal survey or radionuclide bone scan are equivocal. It could also rule out multiple bone involvement and recurrence or regrowth after therapy.
authors.affiliation: Department of Radiology and Ophthalmology, Miyazaki Medical College, Japan.
authors.forename: L G
authors.initials: LG
authors.lastname: Flores
authors.forename: H
authors.initials: H
authors.lastname: Hoshi
authors.forename: S
authors.initials: S
authors.lastname: Nagamachi
authors.forename: T
authors.initials: T
authors.lastname: Ohnishi
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: J
authors.initials: J
authors.lastname: Fukiyama
authors.forename: N
authors.initials: N
authors.lastname: Nao-i
authors.forename: A
authors.initials: A
authors.lastname: Sawada
mesh_terms: D002648:Child; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005624:Frontal Bone / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate; D013794:Thallium Radioisotopes; D014057:Tomography, X-Ray Computed
chemical_list: D013794:Thallium Radioisotopes; D013669:Technetium Tc 99m Medronate