CT-guided pleural needle biopsy in the diagnosis of malignant mesothelioma.
OBJECTIVE
Our goal was to determine the sensitivity of CT-guided closed pleural needle biopsy (CPNB) for the histopathologic diagnosis of diffuse malignant pleural mesothelioma (DMPM).


METHODS
Thirty patients with DMPM were studied with CT-guided CPNB. Tumor specimens were classified according to their cell types.


RESULTS
In 25 (83.3%) patients, the diagnosis was made by CT-guided CPNB. The remaining five patients were diagnosed by thoracoscopy, thoracotomy, or excisional biopsy of the chest wall mass. Pneumothorax was observed in 9.5% of patients and local seeding of tumor in 21.7% of patients who underwent CPNB.


CONCLUSIONS
Properly performed CPNB under CT guidance may yield an increased sensitivity for the diagnosis of diffuse malignant pleural mesothelioma.
Metintaş
M
M
Department of Chest Diseases, Osmangazi University Medical Faculty, Eskişehir, Turkey.
Ozdemir
N
N
Işiksoy
S
S
Kaya
T
T
Ekici
M
M
Erginel
S
S
Harmanci
E
E
Erdinç
P
P
Ulgey
N
N
Alataş
F
F
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*