[The prediction of the individual chemosensitivity of human malignant tumors: the biological patterns and clinical results].
Individual laboratory prediction of the sensitivity of human neoplasms to chemicals is justified on the basis of the authors' own data and those available in the literature. The potentialities and limitations of methods for individual prediction, as well as clinical results are discussed. Data are given on some biological mechanisms responsible for tumor growth which have been obtained in in vitro and in vivo tests with human tumor tissue and carcinoma cells. Further perspectives of this line of studies are discussed.
Chissov
V I
VI
Sergeeva
N S
NS
Borisov
V I
VI
Skotnikova
O I
OI
Sviridova
I K
IK
D000970:Antineoplastic Agents / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004351:Drug Resistance; D004354:Drug Screening Assays, Antitumor / Q000379:methods; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D011379:Prognosis
D000970:Antineoplastic Agents
Prognozirovanie individual'noĭ khimiochuvstvitel'nosti zlokachestvennykh opukholeĭ cheloveka: biologicheskie zakonomernosti i klinicheskie rezul'taty.