title: [Correlation between the gradient constant of the theoretical pressure volume diagram (PVD) and the pressure volume index (PVI) in relation to brain pulse amplitude-mean pressure function].
abstract: In 54 neurosurgical patients--suffering from intracranial tumors, hydrocephalus or different kinds of brain injury--a catheter was implanted in the lateral ventricle for continuously monitoring of the intracranial pressure (ICP). The intraventricular injection of defined amounts of sodium clearance (1-2 cm3) was followed by increased values of intracranial mean pressure--(pm) and pulse-amplitude- (PA). The recorded data showed a high significant correlation after regression analysis. After determination of the pressure-volume-index (PVI) and the theoretical pressure-volume-diagram it was examined whether there is a linear correlation between the parameters of the craniospinal space (id) reserves (constant of gradient, (PVI, K of PVD)) and the gradients (CA) of the linear PA-PM-function. A significant linear relationship, however of weak degree, could be found between these two parameters. The linear PA-PM-function, therefore, can only be understood in restricted circumstances as a direct parameter of the intracranial spacial reserves. The underlying facts of these problems are dealt within this paper.
authors.affiliation: Neurochirurgische Klinik Halle, Martin-Luther-Universität.
authors.forename: A
authors.initials: A
authors.lastname: Rieger
authors.forename: H
authors.initials: H
authors.lastname: Ebel
authors.forename: A
authors.initials: A
authors.lastname: Laun
mesh_terms: D001930:Brain Injuries / Q000503:physiopathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000503:physiopathology* / Q000601:surgery; D002552:Cerebral Ventricles / Q000503:physiopathology; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology*; D003187:Compliance; D006801:Humans; D006849:Hydrocephalus / Q000503:physiopathology* / Q000601:surgery; D007427:Intracranial Pressure / Q000502:physiology*; D008991:Monitoring, Physiologic / Q000295:instrumentation; D011674:Pulse / Q000502:physiology; D012016:Reference Values; D012044:Regression Analysis; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D014696:Ventriculostomy / Q000295:instrumentation
vernacular_title: Korrelation zwischen der Steigungskonstanten des theoretischen Druckvolumendiagramms (PVD) und des Druckvolumenindex (PVI) in Relation zur Hirnpulsamplituden-Mitteldruckfunktion.