title: [Primary seminoma. A rare mediastinal tumor].
abstract: This is a report on three patients with primary mediastinal seminoma. Two patients had no symptoms, and one had had thoracic pain for the last few years. The preoperative diagnosis was thymoma in all cases, and in one patient the radiologist had suspected a seminoma. We removed the tumor after performing median sternotomy (n = 2) and anterolateral left thoracotomy (n = 1). The presence of a primary gonadal seminoma was excluded with a urological and ultrasound examination. All patients are still alive following adjuvant chemotherapy (n = 2; 120 and 8 months) and radiotherapy (n = 1; 84 months). Chemotherapy consisted of four cycles of cisplatin, etoposide and ifosfamide or combination therapy with cisplatin, bleomycin and velbe.
authors.affiliation: Klinik für Thorax- und Kardiovaskuläre Chirurgie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: A
authors.initials: A
authors.lastname: Granetzny
authors.forename: J
authors.initials: J
authors.lastname: Winter
authors.forename: M
authors.initials: M
authors.lastname: Kantartzis
authors.forename: M
authors.initials: M
authors.lastname: Steinbach
authors.forename: F
authors.initials: F
authors.lastname: Borchard
authors.forename: M R
authors.initials: MR
authors.lastname: Jungblut
authors.forename: H D
authors.initials: HD
authors.lastname: Schulte
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D008875:Middle Aged; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D018239:Seminoma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D013908:Thoracotomy
vernacular_title: Das primäre Seminom. Ein seltener mediastinaler Tumor.