title: [Discriminant analytic model for prognostic assessment of pregnancies at risk for premature labor].
abstract: We examined 114 women with preterm labor using discriminance analysis to assess predictive values in terms of prolongation of gestational age and gestational age at the time of delivery. We used parameters like medical history, clinical features, infections, Doppler sonography and cardiotocography. Maternal temperature, cardiotocographic findings, premature rupture of membranes, number of abortions and pregnancy terminations and cervical dilatation at the time of admission contribute significantly to predict prolongation of pregnancy (< or = as well as > 7 days). Our results from this analysis showed sensitivity and specificity of 0.70 and 0.97 and positive and negative predictive values of 0.89 and 0.91, respectively. We observed significant differences concerning parameters like preterm rupture of membranes, cervical dilatation, pathological bacteria in the vagina and pathological Doppler values between subsequent preterm and term deliveries in pregnancies with a prolongation of > 7 days was. Upon reclassifying our results, we obtained sensitivity and specificity of 0.69 and 0.89 and positive and negative predictive values of 0.78 and 0.84, respectively. Early prognostic assessment of preterm labor can be made with discriminance analysis. The results inspire us to perform a prospective examination of the therapy plan that we have obtained.
authors.affiliation: Universitäts-Frauenklinik Leipzig.
authors.forename: R
authors.initials: R
authors.lastname: Faber
authors.forename: B
authors.initials: B
authors.lastname: Viehweg
authors.forename: K
authors.initials: K
authors.lastname: Hiller
mesh_terms: D015148:Cardiotocography / Q000706:statistics & numerical data*; D002821:Chorioamnionitis / Q000150:complications; D016002:Discriminant Analysis; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage; D005322:Premature Rupture of Fetal Membranes / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000502:physiology; D015233:Models, Statistical; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D011237:Predictive Value of Tests; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011446:Prospective Studies; D011673:Pulsatile Flow / Q000502:physiology; D015145:Tocolysis / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal / Q000706:statistics & numerical data*
chemical_list: D005280:Fenoterol
vernacular_title: Diskriminanzanalytisches Modell zur Prognoseeinschätzung bei Schwangerschaften mit drohender Frühgeburt.