title: Lung function after open versus laparoscopic cholecystectomy.
abstract: Postoperative lung function and gas exchange were studied in 36 patients after cholecystectomy. Twenty-four of the patients underwent laparoscopic cholecystectomy while the remaining twelve were operated with open technique. Before surgery all patients had normal ventilatory volumes (forced vital capacity, FVC and forced expired volume in 1 s, FEV1) and normal gas exchange. Two hours postoperatively FVC was reduced to 64 +/- 16% (P < 0.05) of the preoperative level in the laparoscopic group and to 45 +/- 23% (P < 0.05) after open cholecystectomy. On the first postoperative day FVC was virtually normal in the laparoscopic patients (77 +/- 17% of preoperative level, NS), whereas the open surgery patients still had a decreased FVC (56 +/- 13% of preoperative, P < 0.05). FEV1 in the postoperative period followed the same course as FVC. Gas exchange was significantly impaired in the early postoperative period in all patients but no difference between the two groups was found. Two hours postoperatively PaO2 was reduced to 85% (P < 0.05) of preoperative value and PaCO2 had increased by 0.5 kPa (P < 0.05). The alveolo-arterial oxygen tension difference (PA-aO2) had increased by approximately 45% to a mean of 3.7 kPa (P < 0.05). On the first postoperative day gas exchange was still significantly impaired in the open surgery patients. Atelectasis detected by computed X-ray tomography of the lungs were found in both groups. However, the amount of atelectasis tended to be smaller in the laparoscopic group than in the open surgery patients.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Anaesthesiology, Huddinge University Hospital, Karolinska Institute, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Gunnarsson
authors.forename: P
authors.initials: P
authors.lastname: Lindberg
authors.forename: L
authors.initials: L
authors.lastname: Tokics
authors.forename: O
authors.initials: O
authors.lastname: Thorstensson
authors.forename: A
authors.initials: A
authors.lastname: Thörne
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002763:Cholecystectomy; D017081:Cholecystectomy, Laparoscopic; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008875:Middle Aged; D001261:Pulmonary Atelectasis / Q000209:etiology; D011659:Pulmonary Gas Exchange; D014797:Vital Capacity