Endocrine malignancies that may mimic benign lesions.
A variety of malignant tumors that occur in endocrine organs may mimic benign lesions histologically. In this article, a number of such tumors are selected for discussion, including several variants of papillary thyroid carcinoma (encapsulated follicular, diffuse sclerosing, diffuse follicular, macrofollicular, cystic, and stroma-rich), paucicellular anaplastic thyroid carcinoma, primary thyroid low grade B-cell lymphoma of mucosa-associated lymphoid tissue type, adrenocortical carcinoma, and parathyroid carcinoma. Emphasis is placed on the histological clues that are helpful for recognizing the malignant nature of these lesions.
Chan
J K
JK
Department of Pathology, Queen Elizabeth Hospital, Hong Kong.
Tsang
W Y
WY
D000236:Adenoma / Q000473:pathology; D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis / Q000473:pathology*; D018246:Adrenocortical Adenoma / Q000473:pathology; D018268:Adrenocortical Carcinoma / Q000473:pathology; D002291:Carcinoma, Papillary / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000473:pathology; D010282:Parathyroid Neoplasms / Q000175:diagnosis / Q000473:pathology*; D013959:Thyroid Diseases / Q000473:pathology; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000473:pathology*