Efficacy of Cymelarsan in the treatment of natural chronic Trypanosoma evansi infection in camels in the Sudan.
The efficacy of Cymelarsan, administered by intramuscular (i/m) injection in the treatment of chronic cases of camel trypanosomosis due to Trypanosoma evansi, was tested under controlled laboratory conditions. It was confirmed that Cymelarsan is a safe drug for use in dromedary camels when administered i/m at dose rates of 0.25 or 0.50 mg/kg body weight. During the 90 days post-treatment no relapses occurred at either dose rate. Hence, the drug was found to be fully effective against the chronic form of the natural disease. A dose of 0.25 mg/kg body weight of Cymelarsan given i/m is recommended.
Musa
M M
MM
Tsetse and Trypanosomiasis Control Department, Central Veterinary Research Administration, Khartoum, Soudan.
Abdoon
A M
AM
Nasir
B T
BT
Salim
Y I
YI
Abdel-Rahman
A Y
AY
Shommein
A M
AM
D000818:Animals; D001152:Arsenicals / Q000627:therapeutic use*; D002162:Camelus / Q000469:parasitology*; D013397:Sudan; D014344:Trypanocidal Agents / Q000627:therapeutic use*; D014353:Trypanosomiasis, African / Q000188:drug therapy / Q000662:veterinary*
D001152:Arsenicals; D014344:Trypanocidal Agents; C062789:melaminylthioarsenate