title: [Lymphohistiocytic infiltration of endometrial adenocarcinoma].
abstract: Mononuclear cells adjacent to endometrial adenocarcinoma were evaluated in 8 biopsies by the immunoperoxidase technique. Between benign and malignant tissue a remarkable infiltration of CD45+, CD3+, CD4+, CD8+, and CD14+ cells could be observed. B cells (CD19) and NK cells (CD57) were rare. Tumor-infiltrating lymphocytes were only sparsely distributed. The findings suggest a cellular, yet ineffective, immune reaction of the host against the tumor at the borderline between benign and malignant tissue.
authors.affiliation: Hauptabteilung für Gynäkologie der Klinik St. Marienstift.
authors.forename: M
authors.initials: M
authors.lastname: Böhme
authors.forename: M
authors.initials: M
authors.lastname: Löttge
authors.forename: D
authors.initials: D
authors.lastname: Schmidt
authors.forename: I
authors.initials: I
authors.lastname: Röse
authors.forename: W
authors.initials: W
authors.lastname: Weise
authors.forename: J
authors.initials: J
authors.lastname: Morenz
mesh_terms: D000230:Adenocarcinoma / Q000276:immunology / Q000473:pathology*; D000231:Adenocarcinoma, Papillary / Q000276:immunology / Q000473:pathology; D015703:Antigens, CD / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology*; D001706:Biopsy; D018196:Carcinoma, Adenosquamous / Q000276:immunology / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000276:immunology / Q000473:pathology; D016889:Endometrial Neoplasms / Q000276:immunology / Q000473:pathology*; D004717:Endometrium / Q000276:immunology / Q000473:pathology; D005260:Female; D006644:Histiocytes / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D018655:Lymphocyte Count; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology*
chemical_list: D015703:Antigens, CD
vernacular_title: Lymphohistiozytäre Infiltration des endometrialen Adenokarzinoms.