title: Deep dermatophyte infection with chronic draining nodules in an immunocompromised patient.
abstract: Chronic superficial dermatophyte infection may predispose the immunocompromised patient to invasive or disseminated involvement. We report a case of deep dermatophyte infection in a patient treated with long-term corticosteroid therapy for lung disease. The patient responded well to oral griseofulvin. Previously reported cases are reviewed along with recent investigative findings in the pathogenesis of chronic dermatophyte infections. Recommendations are made for diagnosis and therapy.
authors.affiliation: Department of the Army, Fitzsimons Army Medical Center, Aurora, Colorado 80045-5001, USA.
authors.forename: C W
authors.initials: CW
authors.lastname: Demidovich
authors.forename: B W
authors.initials: BW
authors.lastname: Kornfeld
authors.forename: R H
authors.initials: RH
authors.lastname: Gentry
authors.forename: J E
authors.initials: JE
authors.lastname: Fitzpatrick
mesh_terms: D003881:Dermatomycoses / Q000188:drug therapy / Q000473:pathology*; D006118:Griseofulvin / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D007868:Leg Dermatoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology*; D017563:Lung Diseases, Interstitial / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D006118:Griseofulvin; D011241:Prednisone