Corn oil, palm oil and butterfat fractions affect postprandial lipemia and lipoprotein lipase in meal-fed rats.
Our objective was to investigate the time course of postprandial lipemia and lipolytic activity in male Sprague-Dawley rats trained to eat meals containing butterfat fractions, palm oil or corn oil. Baseline and postprandial blood samples were obtained via a carotid cannula in rats fed the experimental diets for 4 wk. Rats fed saturated fats compared with corn oil showed a significantly greater peak increase in postprandial triacylglycerol concentrations. Corn oil ingestion resulted in significantly lower concentrations of cholesterol and triacylglycerol in plasma and significantly less triacylglycerol accumulation (millimoles per liter per 24 h) compared with ingestion of saturated fats. Postheparin plasma lipoprotein lipase activity and plasma insulin concentration were generally greater with ingestion of corn oil compared with palm oil or butterfat. Palm oil ingestion resulted in a biphasic plasma triacylglycerol response curve and greater postheparin plasma lipoprotein lipase activity compared with butterfat ingestion, suggesting differential effects of saturated fats on postprandial lipemia. Our results indicate that greater postprandial lipemia with ingestion of saturated fats compared with corn oil may be due in part to slower plasma triacylglycerol clearance.
Lai
H C
HC
Department of Nutritional Sciences, University of Wisconsin-Madison 53706, USA.
Ney
D M
DM
D000818:Animals; D002079:Butter; D002784:Cholesterol / Q000097:blood; D003314:Corn Oil / Q000494:pharmacology; D004032:Diet / Q000592:standards*; D004041:Dietary Fats / Q000032:analysis / Q000494:pharmacology*; D004435:Eating / Q000502:physiology*; D005990:Glycerol / Q000097:blood; D006128:Growth / Q000187:drug effects / Q000502:physiology; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood*; D008071:Lipoprotein Lipase / Q000097:blood*; D008099:Liver / Q000033:anatomy & histology / Q000737:chemistry; D008297:Male; D019301:Oleic Acid; D009829:Oleic Acids / Q000032:analysis / Q000494:pharmacology; D009929:Organ Size; D000073878:Palm Oil; D019308:Palmitic Acid; D010169:Palmitic Acids / Q000032:analysis / Q000494:pharmacology; D010938:Plant Oils / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013229:Stearic Acids / Q000032:analysis / Q000494:pharmacology; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D004041:Dietary Fats; D007328:Insulin; D008055:Lipids; D009829:Oleic Acids; D010169:Palmitic Acids; D010938:Plant Oils; D013229:Stearic Acids; D014280:Triglycerides; D019301:Oleic Acid; D019308:Palmitic Acid; C031183:stearic acid; D000073878:Palm Oil; D003314:Corn Oil; D002079:Butter; D002784:Cholesterol; D008071:Lipoprotein Lipase; D005990:Glycerol