[The human genome--chromosome 10 and the collagen genes].
In relation to locuses of the 10th chromosome at present the following are in the focus of interest: tumours of endocrine glands, medullary carcinoma of the thyroid gland (MTC) and multiple endocrine neoplasias (MEN). It seems that the unifying basis is the oncogene RET, responsible for the development of Hirschsprung's disease HSCR. The authors mentions also metabolically important locuses for choline acetyltransferase (CHAT), uriporphyrinogen synthase (UROS) and methyl guanine methyltransferase (MGMT). A special paragraph is devoted to a list of collagenous genes COL1-COL18 and diseases associated with them.
Brdicka
R
R
Ustav hematologie a krevní transfuze, Praha.
D002874:Chromosome Mapping; D002879:Chromosomes, Human, Pair 10; D003094:Collagen / Q000235:genetics*; D005826:Genetics, Medical; D006801:Humans
D003094:Collagen
Lidský genom--chromozom c. 10 a kolagenní geny jako prívazek.