title: Trigeminal neuralgia in multiple sclerosis relieved by a prostaglandin E analogue.
abstract: Trigeminal neuralgia is an uncommon but troublesome symptom of multiple sclerosis that can be refractory to conventional treatments. Misoprostol, a long-acting prostaglandin E1 analogue, relieved pain in six of seven patients who had failed to respond to conventional pharmacologic therapy.
authors.affiliation: Department of Neurology, University of Chicago, IL 60637, USA.
authors.forename: A T
authors.initials: AT
authors.lastname: Reder
authors.forename: B G
authors.initials: BG
authors.lastname: Arnason
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016595:Misoprostol / Q000627:therapeutic use*; D009103:Multiple Sclerosis / Q000150:complications*; D011459:Prostaglandins E, Synthetic; D014277:Trigeminal Neuralgia / Q000150:complications / Q000188:drug therapy*
chemical_list: D011459:Prostaglandins E, Synthetic; D016595:Misoprostol