Reversible cyclosporine-induced cortical blindness in allogeneic bone marrow transplant recipients.
We report the occurrence of reversible cyclosporine-induced cortical blindness in three allogeneic bone marrow transplant recipients. Possible mechanisms involved in this rare complication, as well as the associated radiographic and pathologic findings, are discussed.
Memon
M
M
Division of Hematology/Bone Marrow Transplantation, Pittsburgh Cancer Institute, University of Pittsburgh Medical Center, PA 15213-2582, USA.
deMagalhaes-Silverman
M
M
Bloom
E J
EJ
Lister
J
J
Myers
D J
DJ
Pincus
S M
SM
Rybka
W B
WB
Ball
E D
ED
D000328:Adult; D001766:Blindness / Q000139:chemically induced* / Q000473:pathology; D016026:Bone Marrow Transplantation; D016572:Cyclosporine / Q000009:adverse effects*; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control*; D006801:Humans; D008279:Magnetic Resonance Imaging; D014184:Transplantation, Homologous; D014793:Visual Cortex / Q000187:drug effects / Q000473:pathology
D016572:Cyclosporine