A clinically significant interaction between clozapine and valproate.
Costello
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D000328:Adult; D001143:Arousal / Q000187:drug effects*; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D003024:Clozapine / Q000009:adverse effects* / Q000627:therapeutic use; D003221:Confusion / Q000139:chemically induced*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D006801:Humans; D008094:Lithium / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D009949:Orientation / Q000187:drug effects; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology; D013064:Speech Disorders / Q000139:chemically induced*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D014635:Valproic Acid; D008094:Lithium; D003024:Clozapine