title: [Stress reduction through listening to music: effects on stress hormones, hemodynamics and mental state in patients with arterial hypertension and in healthy persons].
abstract: Stress hormones, tissue-plasminogen activator (t-PA) antigen, left-ventricular diastolic function and mood immediately before and after listening to three different kinds of music (a waltz by J. Strauss, a piece of modern classic by H. W. Henze, and meditative music by R. Shankar) were measured in 20 healthy persons (10 women, 10 men; mean age 25 [20-33] years) and 20 hypertensives (8 women, 12 men; mean age 57.5 [25-72] years). To recognise haemodynamic effects, mitral flow by Doppler ultrasound was used as a measure of left-ventricular diastolic function. Atrial filling pressure (AFF) was calculated from the flow integral (VTI) of the early E and the late A waves. The Zerssen scale was used to estimate the immediate mood of the subjects. In hypertensives the levels of cortisol (74 vs 78 ng/ml; P < 0.05) and t-PA antigen (4.3 vs 4.5 ng/ml; P < 0.05) were lower after than before the Strauss waltz. The muscle by Henze lowered the concentrations of cortisol (70 vs 84 ng/ml; P < 0.05), noradrenaline (203 vs 224 ng/l; P < 0.05) and t-PA antigen (4.1 vs 4.6 ng/ml; P < 0.05). After listening to the piece by Shankar the concentrations of cortisol (71 vs 78 ng/ml; P < 0.05), adrenaline 14.5 vs 24.5 ng/ml; P < 0.05) and t-PA antigen (4.2 vs 4.3 ng/ml; P < 0.05) were lower. In healthy subjects AFF (29 vs 26%; P < 0.05) rose after the Strauss music, VTI-E fell (69 vs 73 mm; P < 0.05, while natriuretic peptide rose (63 vs 60 pg/ml; P < 0.05.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Medizinische Klinik und Poliklinik mit Schwerpunkt Nephrologie und Internistische Intensivmedizin, Humboldt-Universität, Berlin.
authors.forename: M
authors.initials: M
authors.lastname: Möckel
authors.forename: T
authors.initials: T
authors.lastname: Störk
authors.forename: J
authors.initials: J
authors.lastname: Vollert
authors.forename: L
authors.initials: L
authors.lastname: Röcker
authors.forename: O
authors.initials: O
authors.lastname: Danne
authors.forename: H
authors.initials: H
authors.lastname: Hochrein
authors.forename: H
authors.initials: H
authors.lastname: Eichstädt
authors.forename: U
authors.initials: U
authors.lastname: Frei
mesh_terms: D000328:Adult; D000339:Affect; D000368:Aged; D009320:Atrial Natriuretic Factor / Q000097:blood; D015150:Echocardiography, Doppler; D004837:Epinephrine / Q000097:blood*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D006973:Hypertension / Q000503:physiopathology; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009146:Music; D009638:Norepinephrine / Q000097:blood; D011581:Psychological Tests; D013312:Stress, Physiological; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000097:blood*
chemical_list: D009320:Atrial Natriuretic Factor; D010959:Tissue Plasminogen Activator; D006854:Hydrocortisone; D009638:Norepinephrine; D004837:Epinephrine
vernacular_title: Stressreduktion durch Musikhören. Einfluss auf Stresshormone, Hämodynamik und psychisches Befinden bei Patienten mit arterieller Hypertonie und bei Gesunden.