title: Metachronous ovarian dysgerminoma after a suprasellar germ-cell tumor treated by radiation therapy. Case report.
abstract: A case of suprasellar germ-cell tumor in a 9-year-old girl who later developed ovarian dysgerminoma is reported. The clinical course of the case is described and a double-primary tumor, rather than metastasis from either tumor to the other, is suggested by the authors to explain the oncogenesis in this patient. The authors strongly encourage that patients with intracranial germinoma be examined for associated extraneural lesions before, as well as after, the completion of the initial therapy.
authors.affiliation: Division of Neurological Surgery, Saitama Children's Medical Center, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Makiyama
authors.forename: H
authors.initials: H
authors.lastname: Nishimoto
authors.forename: M
authors.initials: M
authors.lastname: Matsumoto
authors.forename: A
authors.initials: A
authors.lastname: Kikuchi
authors.forename: T
authors.initials: T
authors.lastname: Tsubokawa
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy*; D002648:Child; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D018237:Germinoma / Q000532:radiotherapy*; D006801:Humans; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000628:therapy; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000628:therapy; D012658:Sella Turcica