title: [Levels of endothelin-1 in bronchoalveolar lavage fluid of patients with bronchial asthma].
abstract: To evaluate the role of endothelin in the pathogenesis of bronchial asthma endothelin-1 levels were studied in the bronchoalveolar lavage fluid of symptomatic (n = 7) and asymptomatic (n = 10) asthmatic patients and healthy volunteers (n = 6). In all patients BAL fluid levels of endothelin-1 was assessed by RIA, total protein concentration by Lowry method. Patients with symptomatic asthma had increased amount of ET-1 in BAL fluid than asymptomatic asthmatics and control group.
  
  
  CONCLUSIONS
  1. Presence of endothelin in BAL fluid indicate that this peptide is involved in the pathogenesis of bronchial asthma. 2. Endothelin-1 BAL fluid levels may correlate with the severity of bronchial asthma.
authors.affiliation: Katedry i Kliniki Chorób Wewnetrznych i Alergologii, Akademii Medycznej w Katowicach.
authors.forename: R
authors.initials: R
authors.lastname: Gawlik
authors.forename: W
authors.initials: W
authors.lastname: Pluskiewicz
authors.forename: D
authors.initials: D
authors.lastname: Ziora
mesh_terms: D000328:Adult; D001249:Asthma / Q000209:etiology / Q000503:physiopathology*; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D016232:Endothelins / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay
chemical_list: D016232:Endothelins
vernacular_title: Zawartość endoteliny-1 w popłuczynach pecherzykowo-oskrzelikowych chorych na astme oskrzelowa.