Absence of human papillomavirus sequences in ovarian pathologies.
The role of human papillomaviruses (HPVs) in ovarian epithelium (either normal or neoplastic) remains controversial. We have investigated by PCR the presence of HPV DNA in fresh tissue from ovarian neoplasms and in primary cell cultures established from either normal, benign or malignant ovarian surface epithelia. None of the fresh samples and primary ovarian cultures contained HPV DNA sequences.
Trottier
A M
AM
Centre de Recherche Louis-Charles Simard/Institut du Cancer de Montréal, Quebec, Canada.
Provencher
D
D
Mes-Masson
A M
AM
Vauclair
R
R
Coutlée
F
F
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002478:Cells, Cultured; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification; D004848:Epithelium / Q000821:virology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000209:etiology / Q000821:virology; D010053:Ovary / Q000821:virology*; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D030361:Papillomavirus Infections / Q000150:complications; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000150:complications
D004279:DNA, Viral