Peripheral blood progenitor cell transplantation for hematological malignancies.
It has been demonstrated that it is possible to mobilize hematopoietic progenitor cells from the bone marrow into the peripheral blood, from which they can be collected by apheresis and used for transplantation. Although the clinical results obtained using this approach have not been compared in a randomized trial to those obtained using bone marrow, it appears that this method has certain advantages. These, together with future developments, are discussed in this review.
Reiffers
J
J
Bone Marrow Transplant Unit, Hôpital Haut-Levêque, Pessac, France.
D015316:Genetic Therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000592:standards* / Q000639:trends*; D006801:Humans; D007938:Leukemia / Q000628:therapy*; D008228:Lymphoma, Non-Hodgkin / Q000628:therapy*; D009101:Multiple Myeloma / Q000628:therapy*