title: [Vulvar involvement in Crohn disease].
abstract: BACKGROUND
  There are many skin manifestations of Crohn's disease including specific lesions occurring late after digestive signs. These manifestations are also termed metastatic and are rarely located on the vulva.
  
  
  METHODS
  We observed a metastatic localization in the vulva of Crohn's disease in a 34-year-old woman with predominantly rectosigmoid disease. The right labia major was greatly enlarged with oedema involving the inguinal cural area. Pustulization and erosive lesions were seen. The course of these lesions was independent of the colonic disease and responded temporarily only to a triple drug combination of metronidazol, prednisolone and minocyclin.
  
  
  CONCLUSIONS
  This case emphasizes the frequency of colonic or rectal manifestations associated with vulval involvement in Crohn's disease. The metastatic lesions follow a course independent of the digestive disease raising therapeutic problems in this localization.
authors.affiliation: Service de Dermatologie, CHU de Nîmes.
authors.forename: S
authors.initials: S
authors.lastname: Doassans
authors.forename: H
authors.initials: H
authors.lastname: Osman
authors.forename: J M
authors.initials: JM
authors.lastname: Joujoux
authors.forename: B
authors.initials: B
authors.lastname: Guillot
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000150:complications*; D004487:Edema / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D014845:Vulvar Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
chemical_list: D008795:Metronidazole
vernacular_title: Atteinte vulvaire au cours d'une maladie de Crohn.