title: Clinical effects of longitudinal division of the corpus callosum in normal dogs.
abstract: Longitudinal division of the corpus callosum was performed in six normal beagles to determine surgical morbidity. The corpus callosum was divided sagittally on the midline and the effect on neurological function was determined. Five of six dogs were clinically normal within 14 days or less after surgery. One dog had persistent but improving clinical signs consistent with a forebrain disturbance at 30 days after surgery. Overall, minimal morbidity and no mortality was associated with this surgical procedure. Further study is indicated to determine the efficacy of this surgical treatment for seizure control in dogs with idiopathic epilepsy.
authors.affiliation: Department of Veterinary Clinical Sciences, Washington State University, College of Veterinary Medicine, Pullman, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Bagley
authors.forename: T V
authors.initials: TV
authors.lastname: Baszler
authors.forename: M L
authors.initials: ML
authors.lastname: Harrington
authors.forename: G E
authors.initials: GE
authors.lastname: Pluhar
authors.forename: M P
authors.initials: MP
authors.lastname: Moore
authors.forename: R D
authors.initials: RD
authors.lastname: Keegan
authors.forename: S A
authors.initials: SA
authors.lastname: Greene
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D003337:Corpus Callosum / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D004283:Dog Diseases / Q000209:etiology / Q000601:surgery; D004285:Dogs / Q000502:physiology / Q000601:surgery*; D004827:Epilepsy / Q000150:complications / Q000601:surgery / Q000662:veterinary; D005240:Feasibility Studies; D009017:Morbidity; D011183:Postoperative Complications / Q000662:veterinary; D012640:Seizures / Q000209:etiology / Q000601:surgery / Q000662:veterinary