Lateral plate mesoderm and guidance cues for cutaneous nerve growth in the avian body wall.
Transplantation of the somatic layer of the lateral plate mesoderm (somatic mesoderm) was performed using the quail-chick chimera system in order to evaluate whether the connective tissue acts as guidance cues for the developing cutaneous nerve in the body wall. When quail somatic mesoderm at the sacro-coccygeal (pudendal) level was transplanted into the chick somatic mesodermal region at the thoracic level, the ventral nerve exhibited the pudendal type of branching pattern in the thoracic region. However, the cutaneous nerve course remained the thoracic type. These results suggest that the connective tissue derived from the somatic mesoderm provides cues for the determination of the nerve branching pattern. In contrast, the pathway selection might require other guidance cues than the somatic mesoderm in the ventral cutaneous nerve growth in the body wall.
Murakami
G
G
Department of Anatomy, Nihon University School of Medicine, Tokyo, Japan.
Kato
Y
Y
Akita
K
K
Sato
T
T
Hoshi
H
H
D000818:Animals; D002642:Chick Embryo; D002678:Chimera; D008648:Mesoderm / Q000502:physiology* / Q000637:transplantation; D017933:Peripheral Nervous System / Q000254:growth & development*; D011784:Quail; D012867:Skin / Q000294:innervation*