[Fulminating malignant hyperthermia in swine--an alternative therapy concept].
An inexpensive therapeutic concept compared to the dantrolene-therapy to counter the malignant hyperthermia (MH) is to be discussed, using a case-study from swine-anaesthesia. Hyperventilating the animals (with O2), administering metamizol, beta-blocker, bicarbonate and sufficiently cooling the patient can, if the symptoms are recognized early enough, arrest the hypermetabolic cascade in its track. All the animals that were treated according to this scheme survived the (MH) crisis without any lasting post operative damage.
Henke
V J
VJ
Institut für Experimentelle Chirurgie, Klinikums rechts der Isar der TU München.
Köhle
M
M
Matiasek
K
K
Beckurts
T E
TE
Sarmiento
A M
AM
Blümel
G
G
Erhardt
W
W
D000818:Animals; D004177:Dipyrone / Q000627:therapeutic use; D005260:Female; D007036:Hypothermia, Induced / Q000662:veterinary; D008305:Malignant Hyperthermia / Q000628:therapy / Q000662:veterinary*; D010102:Oxygen Inhalation Therapy / Q000662:veterinary; D010869:Pindolol / Q000627:therapeutic use; D017693:Sodium Bicarbonate / Q000627:therapeutic use; D013552:Swine; D013553:Swine Diseases / Q000628:therapy*
D004177:Dipyrone; D017693:Sodium Bicarbonate; D010869:Pindolol
Die fulminante maligne Hyperthermie beim Schwein--Ein alternatives Therapiekonzept.