title: Group A beta-hemolytic streptococcal bacteremia in a patient with sickle cell anemia on penicillin prophylaxis.
abstract: Serious invasive bacterial infections, particularly those due to Streptococcus pneumoniae and Hemophilus influenzae, are a well-known complication in patients with sickle cell disease. Early penicillin prophylaxis has been shown to prevent these infections and also to improve survival. This article describes a child with sickle cell anemia who, while on penicillin prophylaxis, developed a group A streptococcal bacteremia, a pathogen not commonly associated with bacteremia in sickle cell disease.
authors.affiliation: Department of Pediatrics, College of Physicians and Surgeons of Columbia University-Harlem Hospital Center, New York, New York 10037, USA.
authors.forename: W
authors.initials: W
authors.lastname: LeBlanc
authors.forename: H
authors.initials: H
authors.lastname: Salah
authors.forename: Y
authors.initials: Y
authors.lastname: Khakoo
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications*; D016470:Bacteremia / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D007223:Infant; D008297:Male; D010406:Penicillins / Q000627:therapeutic use*; D013290:Streptococcal Infections / Q000209:etiology*; D013297:Streptococcus pyogenes
chemical_list: D010406:Penicillins