title: [Examination by image analysis for determining quantitative DNA parameters of serous papillary adenocarcinoma of the endometrium--a single case analysis].
abstract: Serous-papillary adenocarcinoma of the endometrium are rare tumors. We describe DNA-parameters of such a tumor. Imprint-cytologies were taken from 6 different tumor sites (myometrial invasion and 5 additional tumor localizations) and subjected to image-cytophotometry in order to determine their DNA-parameters. All histograms showed an aneuploid DNA-pattern. The DNA-malignancy grade (DNA-MG) was 2.21 +/- 0.11 on median and the 5c exceeding rate (5c ER) was 15.37 +/- 4.17 on median. These results and the slight variability of DNA-pattern at the reported serous-papillary adenocarcinoma support the hypothesis of an own entity of this tumor. Additionally, the high values of DNA-MG and 5c ER confirm the well known aggressive behavior of this tumor entity.
authors.affiliation: Universitätsfrauenklinik, Universität Leipzig.
authors.forename: U
authors.initials: U
authors.lastname: Köhler
authors.forename: L G
authors.initials: LG
authors.lastname: Horn
authors.forename: G
authors.initials: G
authors.lastname: Naumann
authors.forename: H
authors.initials: H
authors.lastname: Nenning
authors.forename: K
authors.initials: K
authors.lastname: Bilek
mesh_terms: D000368:Aged; D018283:Cystadenocarcinoma, Papillary / Q000473:pathology* / Q000601:surgery; D004273:DNA, Neoplasm / Q000032:analysis*; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Bildanalytische Untersuchungen zur Bestimmung quantitativer DNA-Parameter eines serös-papillären Adenokarzinoms des Endometrium--eine Einzelfallanalyse.