[Treatment of orthostatic hypotension with metoclopramide].
A 38 year-old woman, with orthostatic hypotension secondary to autonomic dysfunction accompanied by sympathetic hyperactivity and excess of dopamine, was treated with an antagonistic dopaminergic drug, metoclopramide, 30 mg/day, with good tolerance. Support intervention as well as the use of various drugs (beta-blockers, caffeine, fludrocortisone, haloperidol) showed no effect. The answer to metoclopramide both subjective and objective were remarkable. The way in which metoclopramide acts has not yet been fully clarified. Being a widely used drug, well tolerated, its use must be considered in cases of severe orthostatic hypotension, especially those with an excess of dopamine.
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Instituto de Previdência dos Servidores do Estado de Minas Gerais, Belo Horizonte.
de Albuquerque
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D000328:Adult; D005260:Female; D006801:Humans; D007024:Hypotension, Orthostatic / Q000188:drug therapy*; D008787:Metoclopramide / Q000627:therapeutic use*
D008787:Metoclopramide
Tratamento da hipotensão ortostática com metoclopramida.