title: [Sudanophilic cavitating leukodystrophy: adult familial form].
abstract: Sudanophilic cavitating leukodystrophy is an unusual disorder of the cerebral white matter, clinically characterized by deafness, mental retardation, behavioural alterations and lesions of the descending long tracts. Neuropathological features include: extensive subcortical and deep central demyelination, conspicuous astrocytosis and macro and micro cavitation. We describe a 34 year-old male with personal and family history, clinical features and neuropathological changes consistent with Sudanophilic cavitating leukodystrophy. As far as our knowledge is concerned this constitutes the first report of this entity in Venezuela.
authors.affiliation: Cátedra de Neuroanatomia, Facultad de Medicina, Universidad del Zulia, Venezuela.
authors.forename: G
authors.initials: G
authors.lastname: Luzardo-Small
authors.forename: O
authors.initials: O
authors.lastname: Méndez-Martínez
authors.forename: O
authors.initials: O
authors.lastname: Molina-Viloria
authors.forename: J
authors.initials: J
authors.lastname: Cardozo-Durán
mesh_terms: D000328:Adult; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000473:pathology*; D006801:Humans; D008297:Male
vernacular_title: Leucodistrofia cavitaria sudanofílica: forma familiar adulta.