Protracted febrile myalgia in patients with familial Mediterranean fever.
OBJECTIVE
We describe a newly defined syndrome of protracted febrile myalgia in patients with familial Mediterranean fever (FMF).


METHODS
Fourteen patients with FMF were admitted with an attack of severe disabling myalgia accompanied by fever, high erythrocyte sedimentation rate, and hyperglobulinemia, lasting up to 6 weeks.


RESULTS
Unlike in the classical manifestations of FMF response to corticosteroids therapy was prompt.


CONCLUSIONS
Protracted febrile myalgia is an uncommon dramatic manifestation of FMF that may occur despite colchicine therapy and requires treatment with corticosteroids.
Langevitz
P
P
Heller Institute of Medical Research, Sheba Medical Center, Tel-Aviv University Medical School, Tel-Hashomer, Israel.
Zemer
D
D
Livneh
A
A
Shemer
J
J
Pras
M
M
D000293:Adolescent; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003078:Colchicine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000188:drug therapy / Q000209:etiology*; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D003078:Colchicine; D011241:Prednisone