title: Remodeling mechanisms of transseptal fibers during and after tooth movement.
abstract: The remodeling mechanisms of transseptal fibers during and after tooth movement were investigated histologically. An autoradiographic study was conducted to assess the synthetic response. One hundred fifty male Wistar strain growing rats were divided into three groups--one control and two experimental groups. Animals in the experimental groups were subjected to tooth movement with 25 g and 150 g of force. Maxillary first and second molars were separated and retained mechanically. Transseptal fibers were stretched in proportion to the amount of force applied for up to 2 days. Dynamic remodeling with proliferation of fibroblasts during tooth movement and slow rearrangement during retention periods occurred in both experimental groups. Collagen phagocytosis within the fibroblasts was observed ultrastructurally during the experimental periods. The number of silver grains in fibroblasts in the collagen fibers increased 160% the first day and 206% during the first 3 days. Proliferating fibroblasts remodeled the transseptal fibers through the synthesization and degradation of collagen fibers.
authors.affiliation: Department of Orthodontics, School of Dentistry, University of Tokushima, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Tenshin
authors.forename: M
authors.initials: M
authors.lastname: Tuchihashi
authors.forename: K
authors.initials: K
authors.lastname: Sou
authors.forename: H S
authors.initials: HS
authors.lastname: Lew
authors.forename: H
authors.initials: H
authors.lastname: Hayashi
authors.forename: I
authors.initials: I
authors.lastname: Tanimura
authors.forename: T
authors.initials: T
authors.lastname: Kawata
mesh_terms: D000539:Alveolar Process / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D016723:Bone Remodeling; D003094:Collagen / Q000096:biosynthesis; D003799:Dental Stress Analysis; D005347:Fibroblasts / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D010513:Periodontal Ligament / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D014087:Tooth Movement Techniques
chemical_list: D003094:Collagen