title: [Antibiotic prophylaxis and appendectomy].
abstract: Analysis of clinical studies shows that a single preoperative systematic administration of antibiotics may reduce postoperative sepsis rate after appendicectomy. If the appendix is gangrenous or perforated, this therapy must last for a longer time and is not considered as a prophylaxis. In clinical practice, there are obvious advantages in the use of a single agent efficient against both aerobes and anaerobes. According to the literature, cefotetan or cefoxitin (2 g in adults, 40 mg.kg-1 in children) can be proposed.
authors.affiliation: Service d'Anesthésie-Réanimation Chirurgicale, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg.
authors.forename: T
authors.initials: T
authors.lastname: Pottecher
authors.forename: E
authors.initials: E
authors.lastname: Gogny
authors.forename: L
authors.initials: L
authors.lastname: Pain
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001062:Appendectomy / Q000009:adverse effects; D001064:Appendicitis / Q000601:surgery; D005734:Gangrene / Q000601:surgery; D006801:Humans; D007416:Intestinal Perforation / Q000601:surgery; D011292:Premedication; D012422:Rupture, Spontaneous; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Antibioprophylaxie et appendicectomie.