[Variation of cholostase enzymes (5'-nucleotidase and alkaline phosphatase) during a specific treatment for malaria in the Gabonese child].
Biological variations of 5'nucleotidase (5'NU) and alkaline phosphatase (AP) in 102 Gabonese children with malaria features (MF) and malaria infection (MI) receiving treatment are reported. [formula: see text] During the therapeutic assay, 5'NU rate decreases faster than AP'S; Fourteen days after the beginning of treatment, difference between AP MF and AP M1 is still significant. Enzymes decrease is an indication of the malaria drugs tolerance (MSP (*)).
Ngou-Milama
E
E
Duong
T H
TH
Ozouaki
P
P
Igwangou
P
P
Kombila
M
M
D015720:5'-Nucleotidase / Q000097:blood*; D000469:Alkaline Phosphatase / Q000097:blood*; D000962:Antimalarials / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D005681:Gabon; D006801:Humans; D007223:Infant; D008288:Malaria / Q000188:drug therapy* / Q000201:enzymology*; D015767:Mefloquine / Q000031:analogs & derivatives / Q000627:therapeutic use; D010616:Phenanthrenes / Q000627:therapeutic use; D011739:Pyrimethamine / Q000627:therapeutic use; D012016:Reference Values; D013413:Sulfadoxine / Q000627:therapeutic use; D000096926:Benzenesulfonamides
D015720:5'-Nucleotidase; D000469:Alkaline Phosphatase; D000962:Antimalarials; D004338:Drug Combinations; D015767:Mefloquine; D010616:Phenanthrenes; D011739:Pyrimethamine; D013413:Sulfadoxine; C046846:mefloquine-sulfadoxine-pyrimethamine; D000096926:Benzenesulfonamides; C023768:halofantrine
Variation des enzymes de la cholostase (5'nucléotidase et phosphatase alcaline) au cours d'une thérapeutique curative spécifique du paludisme infection et maladie chez l'enfant Gabonais.