title: Colposcopically directed biopsy and loop excision of the transformation zone. Comparison of histologic findings.
abstract: We performed a retrospective comparison between the findings from colposcopically directed biopsies and those from loop excision of the transformation zone (LETZ) specimens. The correlation was satisfactory. When a low grade squamous intraepithelial lesion (SIL) was predicted on a cytologic smear and biopsy specimen, no cases of invasive carcinoma were found. In two (0.8%) cases in which a high grade SIL was predicted on the cervical smear and biopsy, microinvasive carcinoma was found in the LETZ specimen.
authors.affiliation: Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Ang
authors.forename: R H
authors.initials: RH
authors.lastname: Kaufman
authors.forename: E
authors.initials: E
authors.lastname: Adam
authors.forename: G
authors.initials: G
authors.lastname: Riddle
authors.forename: J F
authors.initials: JF
authors.lastname: Irwin
authors.forename: K O
authors.initials: KO
authors.lastname: Reeves
authors.forename: T L
authors.initials: TL
authors.lastname: Simon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D003127:Colposcopy / Q000379:methods; D004564:Electrocoagulation / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery; D014626:Vaginal Smears / Q000379:methods; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000601:surgery