title: [Something more about adverse reactions to medications].
abstract: OBJECTIVE
  To describe adverse drug effects (ADE) and their frequency in primary care patients.
  
  
  METHODS
  Descriptive and longitudinal study during 1 year (1990).
  
  
  METHODS
  Urban Health Center. Primary Care. Madrid (Spain).
  
  
  METHODS
  15,483 persons, nine general practitioner and one pharmacist.
  
  
  METHODS
  Doctors were invited to register any adverse drug effects they had notice in their patients. Doctors registered information and gave notice to the pharmacist about medicines, dosage and period of administration, clinical manifestations, and improving or not if drug was withdrawal.
  
  
  RESULTS
  326 adverse drugs effects were notified, 30.9 ADE per thousand attended patients. 117 principles actives were involved, and 415 clinical manifestations were registered. The more affected patients were women (2/1). The age groups with higher ADE relative frequencies were children under one year and older people.
  
  
  CONCLUSIONS
  The absolute frequency of medicines involved in ADE are different to relative frequencies when ADE per thousand prescription units are used. Some of the ADE notified were not referred before in the bibliography, so primary care is a good place to research on pharmacosurveillance.
authors.affiliation: Centro de Salud Gómes, Acebo, INSALUD, Area/Sector xi di Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Sáenz Calvo
authors.forename: M
authors.initials: M
authors.lastname: Ausejo Segura
authors.forename: I
authors.initials: I
authors.lastname: Bórdas Rodríguez
authors.forename: R
authors.initials: R
authors.lastname: Acuña Aller
authors.forename: A
authors.initials: A
authors.lastname: Gónzalez Alvaro
authors.forename: B
authors.initials: B
authors.lastname: Bellas Beceiro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged
vernacular_title: Algo más sobre reacciones adversas a medicamentos.