title: Maxillary sinus aspergillosis: diagnosis and differentiation of the pathogenesis based on computed tomography densitometry of sinus concretions.
abstract: OBJECTIVE
  The efficacy of preoperative computed tomography (CT) densitometry in evaluating the origin of sinus concretions (SC) in sinus aspergillosis (SA) and its value for differentiation between a dental (endodontic) and an aerogenic pathogenesis were examined.
  
  
  METHODS
  Thirty-two patients who demonstrated radiodense maxillary sinus concretions in standard radiography underwent an additional preoperative CT examination of the maxillary sinus and the SC. The density of the SC and the root canal filling materials was assessed. The SC were subdivided into organic (< 1,500 HU) and inorganic (> 1,500 HU) masses; this classification was useful in the differentiation between a dental and an aerogenic pathogenesis of SA.
  
  
  RESULTS
  SA was diagnosed in 22 patients (68.8%). The SC of SA patients had a density of 2,566.5 +/- 713.6 HU, whereas those of patients without SA had a density of 1,159.9 +/- 1,008.4 HU (P < .01). A correlation between the density of inorganic SC and that of root filling materials was found (r = .78, P < .01).
  
  
  CONCLUSIONS
  CT densitometry allows a classification of SC into two subgroups. The correlation between the density of root filling materials and that of radiodense sinus concretions seems to point to a "dental" origin of some concretions in SA. However, "organic" masses found in CT densitomentric examinations represent endogenous fungal products, which indicate an aerogenic pathogenesis of SA. Additional CT examinations of radiodense sinus concretions may thus be of some value for diagnosing SA and differentiating their pathogenesis.
authors.affiliation: General Medical Hospital, Wels, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Krennmair
authors.forename: F
authors.initials: F
authors.lastname: Lenglinger
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents; D001228:Aspergillosis / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D002130:Calcium Phosphates; D003907:Dexamethasone; D003937:Diagnosis, Differential; D004338:Drug Combinations; D005260:Female; D005557:Formaldehyde; D006801:Humans; D006854:Hydrocortisone; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D008875:Middle Aged; D010254:Paranasal Sinus Diseases / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D012387:Root Canal Filling Materials; D013943:Thymol / Q000031:analogs & derivatives; D014057:Tomography, X-Ray Computed; D015036:Zinc Phosphate Cement
chemical_list: D000893:Anti-Inflammatory Agents; D002130:Calcium Phosphates; D004338:Drug Combinations; D012387:Root Canal Filling Materials; C485828:alpha-tricalcium phosphate; C011244:corticosteroid methanetriol mixture; C485830:tetracalcium phosphate; D005557:Formaldehyde; D013943:Thymol; C485838:calcium phosphate, monobasic, anhydrous; D015036:Zinc Phosphate Cement; D003907:Dexamethasone; C074226:Harvard Cement; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous; D006854:Hydrocortisone