title: The VEP thresholds for full-field stimuli in dark-adapted infants.
abstract: Dark-adapted adults' electroretinographic b-wave thresholds are approximately 2 log units below a-wave thresholds and approximately 3 log units above the perceptual threshold, and their perceptual and the visually evoked cortical potential (VEP) thresholds are similar. Dark-adapted infants' scotopic a- and b-wave thresholds for full-field stimuli are both about 0.5 log units above those of adults, but their scotopic VEP thresholds for such stimuli have not been studied. We obtained scotopic VEP thresholds for brief, full-field stimuli from dark-adapted, infants and adults to consider the relationships of the cortical responses to the responses of more distal structures, namely the rod photoreceptors (scotopic a-wave) and ON-bipolars (scotopic b-wave). The median VEP threshold of infants is 0.5 log unit above that of adults. Thus, the relationships of a- and b-wave and VEP thresholds in infants are similar to those in adults. These results are consistent with rod cell immaturities being the primary determinant of the difference between infants' and adults' thresholds.
authors.affiliation: Department of Ophthalmology, Children's Hospital, Boston, MA 02115, USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Hansen
authors.forename: A B
authors.initials: AB
authors.lastname: Fulton
mesh_terms: D000293:Adolescent; D000328:Adult; D003623:Dark Adaptation; D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D007223:Infant; D017948:Retinal Rod Photoreceptor Cells / Q000502:physiology; D012684:Sensory Thresholds / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology; D014794:Visual Fields / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*