The inhibitory activity of an HIV type 1 peptide correlates with its ability to interact with a leucine zipper structure.
Wild
C
C
Greenwell
T
T
Shugars
D
D
Rimsky-Clarke
L
L
Matthews
T
T
D000595:Amino Acid Sequence; D000998:Antiviral Agents / Q000494:pharmacology*; D002942:Circular Dichroism; D000077560:Enfuvirtide; D015700:HIV Envelope Protein gp41 / Q000737:chemistry* / Q000494:pharmacology; D015497:HIV-1 / Q000187:drug effects / Q000502:physiology*; D016350:Leucine Zippers / Q000187:drug effects / Q000502:physiology*; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D000998:Antiviral Agents; D015700:HIV Envelope Protein gp41; D010446:Peptide Fragments; D000077560:Enfuvirtide