[Analysis of stationary kinetics of translation elongation within the framework of the stereospecific stabilization hypothesis of codon- anticodon complexes in a ribosome. II. Kinetic schemes in the presence of protein elongation factors and GTP].
Kinetics of the factor-dependent polypeptide elongation is theoretically studied in context of stereospecific stabilization of the codon-anticodon complexes at a ribosome. Kinetic schemes for the different ribosome isomerization stages are examined. The dependence of steady-state elongation rate on elongation factor concentration for each of the schemes is unique, allowing to identify isomerization stages experimentally.
Saĭfullin
S R
SR
Potapov
A P
AP
D000926:Anticodon; D003062:Codon; D006160:Guanosine Triphosphate / Q000737:chemistry*; D007536:Isomerism; D007700:Kinetics; D010445:Peptide Elongation Factors / Q000737:chemistry*; D014176:Protein Biosynthesis; D012346:RNA, Transfer, Amino Acyl / Q000737:chemistry; D012270:Ribosomes / Q000737:chemistry*
D000926:Anticodon; D003062:Codon; D010445:Peptide Elongation Factors; D012346:RNA, Transfer, Amino Acyl; D006160:Guanosine Triphosphate
Analiz statsionarnoĭ kinetiki élongatsii transliatsii v ramkakh gipotezy o stereospetsificheskoĭ stabilizatsii kodon-antikodonovykh kompleksov na ribosome. II. Kineticheskie skhemy v prisutstvii belkovykh faktorov élongatsii i GTP.