[The level of sex steroids in the blood of inbred-strain mice during a normal pregnancy and after zygote retransplantation].
The effect of genotypes on the blood content of progesterone and estradiol was studied in female CBA, C57BL and BALB mice. We also studied progesterone content at the early stages of pregnancy after the effect of stress factors, such as narcosis and surgery, involved in the retransplantation of the embryo from the donor to the recipient. The levels of sex hormones increased during pregnancy with two peaks on the 6-8th and 14-18th days. The pattern of changes in the level of both hormones depends on the female genotype: at some stages, reliable interstrain changes in the blood content of both progesterone and estradiol were found. At the same time, narcosis and bilateral laparotomy did not affect the blood level of progesterone within 12 h after mating, despite marked activation of the adrenocortical system. The data obtained should be taken into account when selecting mother-fetus pairs for retransplantation of embryos in experimental and farm animals.
Serova
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Serova
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Andreeva
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D000818:Animals; D004958:Estradiol / Q000097:blood*; D005260:Female; D005838:Genotype; D051379:Mice; D008815:Mice, Inbred Strains / Q000097:blood*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D011374:Progesterone / Q000097:blood*; D012016:Reference Values; D013997:Time Factors; D015053:Zygote / Q000637:transplantation*
D011374:Progesterone; D004958:Estradiol
Uroven' polovykh steroidov v krovi mysheĭ inbrednykh liniĭ vo vremia normal'noĭ beremennosti i posle retransplantatsii zigot.