title: Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe.
authors.affiliation: Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey 17033, USA.
authors.forename: E S
authors.initials: ES
authors.lastname: Vesell
authors.forename: T D
authors.initials: TD
authors.lastname: Seaton
authors.forename: Y I
authors.initials: YI
authors.lastname: A-Rahim
mesh_terms: D000328:Adult; D002753:Chlorzoxazone / Q000031:analogs & derivatives / Q000097:blood / Q000378:metabolism* / Q000493:pharmacokinetics / Q000652:urine; D019392:Cytochrome P-450 CYP2E1; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D015335:Molecular Probes; D010089:Oxidoreductases, N-Demethylating / Q000235:genetics* / Q000378:metabolism*
chemical_list: D015335:Molecular Probes; C039289:6-hydroxychlorzoxazone; D003577:Cytochrome P-450 Enzyme System; D019392:Cytochrome P-450 CYP2E1; D010089:Oxidoreductases, N-Demethylating; D002753:Chlorzoxazone