[Ca2+ metabolism in the sarcoplasmic reticulum of skeletal muscle after surgical denervation].
The ability of sarcoplasmic reticulum to regulate Ca(2+)-metabolism was studied at different terms after surgical denervation. The increase of Ca(2+)-ATP-ase activity, intensification of active Ca(2+)-accumulation under insignificant change of passive Ca(2+)-outflow from sarcoplasmic reticulum vesicles were observed 3-days after denervation. At more remote terms 14 days and 28 days after denervation all these parameters decreased except for Km: Ca(2+)-ATP activity and active Ca2+ accumulation decreased below normal level.
Brazaluk
A Z
AZ
Kurskiĭ
M D
MD
Fedorov
A N
AN
Deforova
L K
LK
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D009121:Muscle Denervation; D018482:Muscle, Skeletal / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D012519:Sarcoplasmic Reticulum / Q000378:metabolism*
D000252:Calcium-Transporting ATPases; D002118:Calcium
Obmen Ca2+ v sarkoplazmaticheskom retikulume skeletnykh myshts pri khirurgicheskoĭ denervatsii.