title: Changes of gastric acid secretion and somatostatin after Roux-en-Y cholangiojejunostomy.
abstract: The authors studied the changes of gastric acid secretion and determined the levels of somatostatin (SS) and gastrin (Gn) in blood, gastric juice and pyloric antrum in 28 patients Roux-en-Y with cholangiojejunostomy (CJR-Y). Gastric acid hypersecretion was identified, and the level of SS was found dropped while the content of Gn increased in these specimens. It was considered that the reduction of SS synthesis and secretion might have a key effect on the mechanism of secondary gastric acid hypersecretion in patients after CJR-Y.
authors.affiliation: Department of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical College, Chongqing.
authors.forename: K
authors.initials: K
authors.lastname: Ma
authors.forename: G
authors.initials: G
authors.lastname: Qian
authors.forename: Z
authors.initials: Z
authors.lastname: He
authors.forename: A
authors.initials: A
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000713:Anastomosis, Roux-en-Y / Q000379:methods; D001652:Bile Ducts / Q000601:surgery*; D001660:Biliary Tract Diseases / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005755:Gastrins / Q000097:blood*; D006801:Humans; D007583:Jejunum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013004:Somatostatin / Q000097:blood*
chemical_list: D005755:Gastrins; D013004:Somatostatin