title: Pulmonary damage due to paraquat poisoning through skin absorption.
abstract: A case of recovery from acute respiratory insufficiency due to paraquat is described. A 57-year-old farmer developed breathlessness, high fever and interstitial infiltrates in the upper and middle lung fields few days after percutaneous paraquat poisoning with rapid evolution to pulmonary fibrosis. Anti-inflammatory drugs and antioxidants, were administered to the patient, though with a delay, with some improvement; the patient survived despite residual lung fibrosis. Paraquat lung, as confirmed by this paper, is not invariably fatal.
authors.affiliation: Department of Internal Medicine, University of Ioannina, Greece.
authors.forename: S A
authors.initials: SA
authors.lastname: Papiris
authors.forename: M A
authors.initials: MA
authors.lastname: Maniati
authors.forename: V
authors.initials: V
authors.lastname: Kyriakidis
authors.forename: S H
authors.initials: SH
authors.lastname: Constantopoulos
mesh_terms: D000208:Acute Disease; D000382:Agricultural Workers' Diseases / Q000139:chemically induced*; D001205:Ascorbic Acid / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D010269:Paraquat / Q000493:pharmacokinetics* / Q000506:poisoning*; D011041:Poisoning / Q000188:drug therapy; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000188:drug therapy; D012869:Skin Absorption; D014810:Vitamin E / Q000627:therapeutic use
chemical_list: D014810:Vitamin E; D010269:Paraquat; D001205:Ascorbic Acid; D008775:Methylprednisolone