Clinical evaluation of gastric fundic gland polyps without familial polyposis coli.
BACKGROUND
Assessments were made of 63 cases of fundic gland polyposis (FGP) unassociated with adenomatosis coli. These cases were evaluated by radiological examination over 2 years follow-up. All polyps were pathologically confirmed by endoscopic biopsies.


METHODS
Most cases were asymptomatic when diagnosed during mass radiological surveys of the upper gastrointestinal tract. The majority of patients ranged in age from 40-60 years, and the polyps numbered fewer than 20 in 55 cases (87.3%). Polyps were detected in the fundic glands using the congo red test and by biopsies.


RESULTS
All serum gastrin values were within the normal range. During the course of this study, the polyps of 13 cases (20.6%) increased and those of three cases (4.8%) decreased or resolved completely.


CONCLUSIONS
From these findings it is considered that FGP are observed in stomachs with less atrophy, and that polyps follow courses in which they increase, decrease, disappear, along with atrophy.
Tsuchigame
T
T
Department of Radiology, Kumamoto University Medical School, Japan.
Saito
R
R
Ogata
Y
Y
Ueno
S
S
Arakawa
A
A
Matsukawa
T
T
Furusawa
M
M
Urata
J
J
Takahashi
M
M
D011125:Adenomatous Polyposis Coli / Q000175:diagnosis; D000293:Adolescent; D000328:Adult; D000368:Aged; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005748:Gastric Fundus / Q000000981:diagnostic imaging / Q000473:pathology*; D005753:Gastric Mucosa / Q000000981:diagnostic imaging / Q000473:pathology*; D005755:Gastrins / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography; D013274:Stomach Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging
D005755:Gastrins