Aminoacyl-tRNA synthetases.
Detailed mechanisms for each step of the reaction catalyzed by both class I and class II aminoacyl-tRNA synthetases have been proposed on the basis of crystallographic data of aminoacyl-tRNA synthetases in complex with their different substrates. Despite the very different topologies of the two classes, there are striking and unanticipated chemical similarities between their active sites and proposed mechanisms.
Delarue
M
M
Unité d'Immunologie Structurale, Institut Pasteur, Paris, France.
D000595:Amino Acid Sequence; D000604:Amino Acyl-tRNA Synthetases / Q000737:chemistry* / Q000378:metabolism*; D008969:Molecular Sequence Data
D000604:Amino Acyl-tRNA Synthetases