title: [Total thyroidectomy in a young girl presenting C cell hyperplasia at the time of a family screening for medullary carcinoma of the thyroid gland].
abstract: The authors report on the case of a 5,8 year-old girl whose father died of medullary thyroid carcinoma. When she was 4,5 year-old, her physical examination was normal but plasma calcitonin and katacalcin (PDN-21) levels were abnormally high in response to pentagastrin infusion. Total thyroidectomy was performed and immunohistochemical staining showed confluent C-cell hyperplasia. No recurrence occurred in this patient over four years on follow-up.
authors.affiliation: Unité d'endocrinologie, Cliniques Universitaires Saint-Luc, Brussels, Belgique.
authors.forename: B
authors.initials: B
authors.lastname: Brichard
authors.forename: B
authors.initials: B
authors.lastname: Henrot
authors.forename: M
authors.initials: M
authors.lastname: Maes
authors.forename: J
authors.initials: J
authors.lastname: Rahier
authors.forename: C
authors.initials: C
authors.lastname: Jonard
authors.forename: P
authors.initials: P
authors.lastname: Malvaux
mesh_terms: D018276:Carcinoma, Medullary / Q000175:diagnosis / Q000235:genetics; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006965:Hyperplasia; D013961:Thyroid Gland / Q000473:pathology* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000235:genetics; D013965:Thyroidectomy
vernacular_title: Thyroïdectomie totale chez une fillette présentant une hyperplasie des cellules C dans le cadre d'un dépistage familial de carcinome médullaire de la thyroïde.