A novel sequence polymorphism in exon 8 of the human vitamin D-binding protein (GC) gene in an African population.
A novel sequence polymorphism due to a T to C transition at the third nucleotide of the codon for Cys283 of the vitamin D-binding protein (GC) gene assigned to chromosome 4q13-4q21.1 was revealed by sequence analysis. Population studies by single strand conformation polymorphism (SSCP) analysis showed this GC-283.3 site was polymorphic in a Black African population but monomorphic in a European population.
Yuasa
I
I
Department of Legal Medicine, Tottori University School of Medicine, Yonago, Japan.
Kofler
A
A
Braun
A
A
Bichlmaier
R
R
Kammerer
S
S
Cleve
H
H
D001483:Base Sequence; D044383:Black People / Q000235:genetics*; D002894:Chromosomes, Human, Pair 4; D005091:Exons; D005787:Gene Frequency; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D014809:Vitamin D-Binding Protein / Q000235:genetics*
D014809:Vitamin D-Binding Protein