Beneficial effect of growth hormone on atherogenic risk in children with growth hormone deficiency.
We studied changes in the atherogenic index (total cholesterol divided by high-density lipoprotein cholesterol) in 12 prepubertal boys with growth hormone (GH) deficiency during 9 months of GH treatment. High-density lipoprotein cholesterol level increased until 5 months without significant changes in total cholesterol level; thus GH therapy may be beneficial in reducing the atherogenic index in boys with GH deficiency.
Kohno
H
H
Department of Endocrinology and Metabolism, Fukuoka Children's Hospital, Japan.
Ueyama
N
N
Yanai
S
S
Ukaji
K
K
Honda
S
S
D000293:Adolescent; D001161:Arteriosclerosis / Q000517:prevention & control*; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D013006:Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use; D012307:Risk Factors
D008076:Cholesterol, HDL; D011994:Recombinant Proteins; D013006:Growth Hormone; D002784:Cholesterol