title: Yunnanxane and its homologous esters from cell cultures of Taxus chinensis var. mairei.
abstract: From cell cultures of Taxus chinensis var. mairei, yunnanxane [2 alpha, 5 alpha, 10-beta triacetoxy-14 beta-(2'-methyl-3'-hydroxyl)-butyryloxy-4(20),11-taxadiene, [1], and four new homologous esters, 2 alpha, 5 alpha, 10 beta, 14 beta- tetra-acetoxy-4(20),11-taxadiene [2], 2 alpha, 5 alpha, 10 beta- triacetoxy-14 beta-propionyloxy-4(20),11-taxadiene [3], 2 alpha, 5 alpha, 10 beta- triacetoxy-14 beta-isobutyryloxy-4(20),11- taxadiene [4], and 2 alpha, 5 alpha, 10 beta- triacetoxy-14 beta-(2'-methyl)-butyryloxy-4(20),11- taxadiene [5] have been isolated. Their structures were determined by spectroscopic methods.
authors.affiliation: PHYTOpharmaceuticals, Inc., San Carlos, California 94070-3312.
authors.forename: W
authors.initials: W
authors.lastname: Ma
authors.forename: R W
authors.initials: RW
authors.lastname: Stahlhut
authors.forename: T L
authors.initials: TL
authors.lastname: Adams
authors.forename: G L
authors.initials: GL
authors.lastname: Park
authors.forename: W A
authors.initials: WA
authors.lastname: Evans
authors.forename: S G
authors.initials: SG
authors.lastname: Blumenthal
authors.forename: G A
authors.initials: GA
authors.lastname: Gomez
authors.forename: M H
authors.initials: MH
authors.lastname: Nieder
authors.forename: P J
authors.initials: PJ
authors.lastname: Hylands
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000096:biosynthesis / Q000737:chemistry*; D002478:Cells, Cultured; D004224:Diterpenes / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D004952:Esters; D009682:Magnetic Resonance Spectroscopy; D018547:Plant Stems / Q000166:cytology / Q000378:metabolism
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D004952:Esters; C076298:yunnanxane