Hematuria home screening: repeat testing results.
To determine at what interval screening should be repeated to detect bladder cancer before it becomes muscle invasive 856 men who had 14 negative daily home tests for hematuria with a chemical reagent strip 9 months previously performed repeat tests. Of these men 50 (5.8%) had at least 1 positive test during the second 14-day screening period and 38 were evaluated, 15 of whom (39.5%) had significant urological pathological conditions, including 8 with malignancies. Bladder cancer was noted in 7 men, with no tumor invading the muscularis propria. The finding of 7 bladder cancers in 856 men (0.82%) who had a negative test 9 months previously indicates that bladder cancer has a brief preclinical duration and that testing must be repeated at least annually for screening to detect bladder cancer consistently before invasion occurs.
Messing
E M
EM
Department of Surgery, University of Wisconsin, Madison, USA.
Young
T B
TB
Hunt
V B
VB
Newton
M A
MA
Bram
L L
LL
Vaillancourt
A
A
Hisgen
W J
WJ
Greenberg
E B
EB
Kuglitsch
M E
ME
Wegenke
J D
JD
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000473:pathology; D003365:Costs and Cost Analysis; D005500:Follow-Up Studies; D006417:Hematuria / Q000175:diagnosis*; D006801:Humans; D007669:Kidney Calculi / Q000175:diagnosis; D008297:Male; D008403:Mass Screening / Q000191:economics; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology; D011934:Reagent Strips / Q000191:economics; D015203:Reproducibility of Results; D012648:Self Care; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000517:prevention & control*; D014552:Urinary Tract Infections / Q000175:diagnosis
D011934:Reagent Strips