Tumor suppressor gene alterations in bladder carcinoma. Translational correlates to clinical practice.
The most common tumor suppressor genes involved in the prediction of bladder tumor progression are the Rb and the p53 genes. This article summarizes current data on the use of these markers in prognostic evaluation.
Dalbagni
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Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Cordon-Cardo
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C
Reuter
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Fair
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WR
D002277:Carcinoma / Q000235:genetics* / Q000473:pathology*; D015972:Gene Expression Regulation, Neoplastic; D016161:Genes, Retinoblastoma / Q000235:genetics; D016147:Genes, Tumor Suppressor / Q000235:genetics*; D016158:Genes, p53 / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000473:pathology*
D005819:Genetic Markers