title: Pharmacotherapy of depression in children.
abstract: Depression can interfere with the overall functioning of children and adolescents. It can impair normal cognitive and social development. The use of antidepressant medications in children and adolescents has grown in the past decade. Newer antidepressant agents, the selective serotonin reuptake inhibitors, appear very promising, but their safety and efficacy have not been established for children. This review focuses on depression and the design of studies for its treatment with newer antidepressant drugs in children.
authors.affiliation: LSU Medical Center, Department of Pediatrics, Shreveport 71130-3932, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Wilson
authors.forename: R C
authors.initials: RC
authors.lastname: Parish
authors.forename: A
authors.initials: A
authors.lastname: del Mundo
authors.forename: J R
authors.initials: JR
authors.lastname: Donaldson
authors.forename: V
authors.initials: V
authors.lastname: Johnson
mesh_terms: D000293:Adolescent; D000328:Adult; D000928:Antidepressive Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002648:Child; D003863:Depression / Q000188:drug therapy*; D006801:Humans; D012107:Research Design
chemical_list: D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic