Five years survival result of twenty-two breast cancers treated by breast conserving therapy at NCI Bangkok.
From November 1984 to July 1992 Breast Conserving Therapy (BCT) has been offered to clinical stage 1 & 2 breast cancers. Twenty two breast cancers were treated and passed the five year period. Only one patient was lost in follow-up. The treatment consisted of tumorectomy, full axillary nodal dissection and total breast irradiation with a booster dose at the biopsy site. Adjuvant chemotherapy is administered in cases of positive axillary nodes. There are seventeen living and four deaths. The 5 year survival was 80.95 per cent. The four deaths were node negative and in the young age group (under 36 years of age). Three out of four who died of distant metastasis showed precedent local recurrence. Local recurrence was noted in four patients (19.04%). Second primary breast cancers were found in four patients and two of them died of distant metastasis and one of these two had local recurrence in the first breast carcinoma. There were two survivors from distant metastasis, one with single pulmonary metastasis and another with spine and pelvic bony metastases. Slight to moderate arm edema was found in 5 patients. (22.73%). From our study we have been convinced that BCT seems to give poorer results in terms of survival in the young age group (especially under 36 years of age). Those who are under 36 years of age and have T2 lesion with negative node or local recurrence as well as second primary breast carcinoma should receive adjuvant chemotherapy.
Chindavijak
K
K
National Cancer Institute, Bangkok, Thailand.
Puribhat
S
S
Chiersilpa
A
A
D000328:Adult; D001943:Breast Neoplasms / Q000401:mortality / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D015412:Mastectomy, Segmental; D008875:Middle Aged; D015996:Survival Rate