title: [Nitrogen oxide inhalation in acute pulmonary failure].
abstract: Two cases of adult respiratory distress syndrome (ARDS) treated successfully with nitric oxide (NO) inhalation are described. One patient had severe sepsis and the other had trauma induced ARDS. The slow entry criteria for extracorporeal membrane oxygenation (ECMO) was fulfilled in both cases. NO inhalation substantially improved oxygenation, reduced pulmonary arterial pressure and peak inspiratory pressure. Treatment with NO inhalation was without side effects and easy to administer through the ventilator. Both patients survived without sequelae. We suggest that inhalation with NO should be tried before ECMO treatment is considered in severe ARDS.
authors.affiliation: Intensiv Afdeling, Rigshospitalet, København.
authors.forename: T H
authors.initials: TH
authors.lastname: Jensen
authors.forename: S W
authors.initials: SW
authors.lastname: Henneberg
authors.forename: L
authors.initials: L
authors.lastname: Heslet
authors.forename: P K
authors.initials: PK
authors.lastname: Andersen
mesh_terms: D000293:Adolescent; D000328:Adult; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006801:Humans; D008297:Male; D009569:Nitric Oxide / Q000008:administration & dosage*; D012128:Respiratory Distress Syndrome / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D009569:Nitric Oxide
vernacular_title: Nitrogenoxidinhalation ved akut lungesvigt.