Antioxidative activity of hop bitter acids and their analogues.
Hop bitter acids, humulones (1) and lupulones (2), were shown to have potent DPPH radical scavenging activity (RSA) and lipid peroxidation inhibitory activity (LIA). Furthermore, 5-acetyl lupulones (3) and 4-methyl lupulones (4) had more potent LIA than native lupulones but no RSA. This result indicates that the beta, beta'-triketone moiety of the lupulones has LIA.
Tagashira
M
M
Central Research Laboratories, Asahi Breweries Ltd., Tokyo, Japan.
Watanabe
M
M
Uemitsu
N
N
D000975:Antioxidants / Q000494:pharmacology*; D053138:Cyclohexenes; D016166:Free Radical Scavengers; D010944:Plants / Q000737:chemistry*; D013729:Terpenes / Q000494:pharmacology
D000975:Antioxidants; D053138:Cyclohexenes; D016166:Free Radical Scavengers; D013729:Terpenes; C008299:lupulon; C007966:humulon