title: Quality of Life assessments in the evaluation of gastroesophageal reflux and peptic ulcer disease before, during and after treatment.
abstract: BACKGROUND
  It has recently been suggested that Quality of Life (QOL) be used in the evaluation of new medical treatment regimens together with cost-benefit, efficacy and safety. In this overview we point out some aspects of use of the Psychological General Well-Being Index (PGWB) in patients with peptic ulcer and reflux disease gained from our own investigations in later years.
  
  
  METHODS
  QOL was assessed using questionnaires before diagnosis, during medical healing treatment and at a 1-year follow-up in peptic ulcer disease or before and after surgery in reflux disease.
  
  
  RESULTS
  Untreated patients with unknown diagnosis had low QOL scores. With treatment, scores increased rapidly to supernormal values and fell off to normal values during the follow-up year.
  
  
  CONCLUSIONS
  QOL evaluations seem sensitive and reflect the patient's subjective feeling of disease. They add another new aspect of treatment effect not earlier included in treatment evaluations.
authors.affiliation: Dept. of Surgery, NAL., Trollhättan, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Glise
authors.forename: B
authors.initials: B
authors.lastname: Hallerbäck
authors.forename: B
authors.initials: B
authors.lastname: Johansson
mesh_terms: D005260:Female; D005764:Gastroesophageal Reflux / Q000523:psychology / Q000628:therapy*; D006801:Humans; D008297:Male; D010437:Peptic Ulcer / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D011795:Surveys and Questionnaires