title: Endemic goiter in the Lemanak and Ai river villages of Sarawak.
abstract: In a survey of 974 villagers (408 males, 566 females; ages = 11-82 years) of the Ai (n = 496; 212 males, 284 females) and Lemanak (n = 478; 196 males, 282 females) rivers in the district of Lubuk Antu in Sarawak's Sri Aman Division during July 1993, goiter was found in 31.8% of the subjects. The goiter prevalence was higher in the more interior Ai river area than in the Lemanak river area (36.9% vs 26.5%). In females aged 15 years and above, the goiter prevalence was 75.4% and 49.1%, respectively, in the Ai and Lemanak river areas. The difference in goiter prevalence between the two areas was related to the degree of iodine deficiency in the two areas. The median urinary iodine excretion in the Ai river villagers was 22.1 micrograms/l compared to 72.9 micrograms/l in the Lemanak river villagers (p < 0.0001). Goitrous subjects tended to have lower urinary iodine concentration than non-goitrous subjects. In the males, smoking of tobacco was associated with a two-fold increase in goiter frequency. Despite on-going distribution of iodized salt by the medical and health services in the State, only 23% of the 135 salt samples obtained from the households in the areas contained detectable iodine.
authors.affiliation: Institute for Medical Research, Kuala Lumpur, Malaysia.
authors.forename: L C
authors.initials: LC
authors.lastname: Foo
authors.forename: T
authors.initials: T
authors.lastname: Zainab
authors.forename: G R
authors.initials: GR
authors.lastname: Letchuman
authors.forename: M
authors.initials: M
authors.lastname: Nafikudin
authors.forename: R
authors.initials: R
authors.lastname: Azriman
authors.forename: P
authors.initials: P
authors.lastname: Doraisingam
authors.forename: A K
authors.initials: AK
authors.lastname: Khalid
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006043:Goiter, Endemic / Q000453:epidemiology*; D006801:Humans; D007455:Iodine; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012423:Rural Health; D012907:Smoking; D017673:Sodium Chloride, Dietary
chemical_list: D017673:Sodium Chloride, Dietary; D007455:Iodine