title: [Treatment of swine with chronic pneumonia with chlortetracycline-medicated feed].
abstract: 26 fattening pigs with spontaneous severe chronic bronchopneumonitis were orally treated with feed containing 800 ppm chlortetracycline (CTC) over 3 weeks. With the help of clinical investigation, transcutaneous measurement of the oxygen-saturation of the blood, X-ray of the thorax and bronchoalveolar lavage significant effects could be measured during and after finishing the treatment. In 19 spontaneous fallen ill untreated control animals recovery could not be detected by the used methods. After the end of the 3 weeks interval there were significant differences between treated and untreated animals detectable. By this investigations practical observations that oral treatment with 800 ppm in fattening pigs is effective was verified. But because of pharmacokinetic data higher concentrations would be recommendable. In the treated pigs a significant increase of the oxygen saturation of the blood occurred not before the 8th day of treatment. This underlines the importance of sufficient length of the treatment interval.
authors.affiliation: Klinik für kleine Klauentiere, Tierärztlichen Hochschule Hannover.
authors.forename: M
authors.initials: M
authors.lastname: Ganter
authors.forename: D
authors.initials: D
authors.lastname: Dudziak
authors.forename: F
authors.initials: F
authors.lastname: Delbeck
mesh_terms: D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D002751:Chlortetracycline / Q000008:administration & dosage / Q000627:therapeutic use*; D002908:Chronic Disease; D018410:Pneumonia, Bacterial / Q000188:drug therapy / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy*
chemical_list: D002751:Chlortetracycline
vernacular_title: Behandlungsergebnisse mit der Chlortetracyclin-Futtermedikation bei chronisch Pneumonie-kranken Schweinen.