title: Ex vivo and in vitro models in acetaminophen hepatotoxicity studies. Relationship between glutathione depletion, oxidative stress and disturbances in calcium homeostasis and energy metabolism.
authors.affiliation: Université René-Descartes, Faculté de Pharmacie, Laboratoire de Toxicologie, France.
authors.forename: S
authors.initials: S
authors.lastname: Ellouk-Achard
authors.forename: V
authors.initials: V
authors.lastname: Levresse
authors.forename: C
authors.initials: C
authors.lastname: Martin
authors.forename: C
authors.initials: C
authors.lastname: Pham-Huy
authors.forename: H
authors.initials: H
authors.lastname: Dutertre-Catella
authors.forename: M
authors.initials: M
authors.lastname: Thevenin
authors.forename: J M
authors.initials: JM
authors.lastname: Warnet
authors.forename: J R
authors.initials: JR
authors.lastname: Claude
mesh_terms: D000082:Acetaminophen / Q000633:toxicity*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002330:Carmustine / Q000494:pharmacology; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000378:metabolism*; D003600:Cytosol / Q000201:enzymology; D004734:Energy Metabolism / Q000187:drug effects*; D005978:Glutathione / Q000378:metabolism*; D005980:Glutathione Reductase / Q000037:antagonists & inhibitors; D006706:Homeostasis / Q000187:drug effects; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000082:Acetaminophen; D008748:Methylcholanthrene; D005980:Glutathione Reductase; D005978:Glutathione; D002118:Calcium; D002330:Carmustine