Some evidence in favour of the partnership between rabbit muscle aldolase and glyceraldehyde 3-phosphate dehydrogenase in the consecutive reactions.
An additional indication in favour of interaction between sequential glycolytic enzymes is provided by the mutual enhancement of aldolase and glyceraldehyde 3-phosphate dehydrogenase activities. The efficiency of aldolase as the activator is progressively affected by the presence of its substrate, fructose-1,6-diphosphate, and its structural analogue, hexitol-1,6-diphosphate. Such interrelation of two sequential glycolytic enzymes can originate from their conformational interadjustment for the subsequent metabolic channeling between them.
Chumachenko
Y V
YV
Palladin Institute of Biochemistry, Kyĩv.
D000818:Animals; D004795:Enzyme Stability; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism*; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000378:metabolism*; D006019:Glycolysis / Q000502:physiology*; D007700:Kinetics; D009132:Muscles / Q000201:enzymology*; D011817:Rabbits
D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D005634:Fructose-Bisphosphate Aldolase