[Role of S'2-stimulation of serine proteases in regulation of proteolysis].
Data about ligand specificity and functionality of the nearest surrounding of hydrolytic centre of serine proteases are presented. A regulatory role of S'2-site predetermining highly-specific activation of proenzymes into the enzymes and formation of stable enzyme-serine complexes is discussed.
Verevka
S V
SV
Sytnik
A I
AI
Kolodzeĭskaia
M V
MV
D000818:Animals; D001665:Binding Sites; D004789:Enzyme Activation; D006801:Humans; D006868:Hydrolysis; D015394:Molecular Structure; D012697:Serine Endopeptidases / Q000187:drug effects*; D013268:Stimulation, Chemical
D012697:Serine Endopeptidases
O roli S'2-stimululiatsii serinovykh proteaz v reguliatsii proteoliza.