Early inflammatory response to gelatin- and collagen-sealed Dacron prostheses.
The immediate inflammatory response following aortic reconstruction with two types of sealed Dacron grafts was studied in a prospective, randomized manner. C-reactive protein (CRP) levels were measured before surgery and on days 2 and 8 postoperatively. In the collagen-sealed group (n = 10) CRP levels were 10 +/- 9.6, 180.2 +/- 48.3, and 54.3 +/- 34.3 mg/L, respectively. In the gelatin-impregnated group (n = 10) the values were 10.5 +/- 8.7, 200.7 +/- 27.3, and 80.3 +/- 30.2 mg/L, respectively. The slight differences were not significant according to the analysis of variance test for repeated measurements. These findings suggest that implantation of a knitted Dacron graft sealed with collagen does not lead to a higher inflammatory reaction compared with a gelatin-sealed graft.
Lacroix
H
H
Department of Vascular Surgery, Universitaire Ziekenhuizen KUL, Katholieke Universiteit, Leuven, Belgium.
Boel
K
K
Nevelsteen
A
A
Suy
R
R
D000368:Aged; D000704:Analysis of Variance; D001012:Aorta, Abdominal / Q000601:surgery; D001025:Aortitis / Q000097:blood / Q000209:etiology*; D001672:Biocompatible Materials; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D001831:Body Temperature; D002097:C-Reactive Protein / Q000378:metabolism; D003094:Collagen / Q000009:adverse effects*; D005780:Gelatin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D011446:Prospective Studies
D001672:Biocompatible Materials; D011093:Polyethylene Terephthalates; D005780:Gelatin; D003094:Collagen; D002097:C-Reactive Protein