[Positive tuberculin reaction in sarcoidosis].
Scar sarcoidosis is one of the rare cutaneous manifestations of sarcoidosis. Apart from the clinical picture, suppression of the cell-mediated immunity can often be determined when tuberculin tests and testing for recall antigens are carried out. In the present case of a 68-year-old woman patient scar sarcoidosis and pulmonary sarcoidosis were detected. Remarkably, a strongly positive tuberculin reaction was found, while acute tuberculosis and former BCG vaccination were excluded. Both references in the literature and the case presented demonstrate that a positive tuberculin test, while very unusual in sarcoidosis, does not however, preclude the diagnosis. On the basis of some case reports in the literature, our patient was treated with allopurinol; impressive improvement of both the skin and the pulmonary manifestations was noted. Despite the well-known phenomenon of spontaneous regression in sarcoidosis, we recommend a clinical trial with allopurinol as this substance is well tolerated.
Pfau
A
A
Dermatologische Klinik und Poliklinik, Universität, Regensburg.
Abd-el-Raheem
T
T
Landthaler
M
M
D000493:Allopurinol / Q000008:administration & dosage; D002921:Cicatrix / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000276:immunology / Q000473:pathology; D014374:Tuberculin Test
D000493:Allopurinol
Positive Tuberkulinreaktion bei Sarkoidose.