Cytogenetic analysis of children suspected of chromosomal abnormalities.
Karyotypes were examined in 122 Omani children suspected of having chromosomal abnormalities. A total of 50 (41 per cent) had an abnormal karyotype: 38 (31 per cent) were Down's syndrome whilst a further 12 (10 per cent) had other types of chromosomal abnormalities. These findings suggest that cytogenetic analysis is useful in the investigations of children with congenital anomalies of unknown origin; to confirm clinical diagnosis in children with known cytogenetic syndromes and for genetic counselling.
Kenue
R K
RK
Department of Human & Clinical Anatomy, College of Medicine, Sultan Qaboos University, Sultanate of Oman.
Raj
A K
AK
Harris
P F
PF
el-Bualy
M S
MS
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000453:epidemiology / Q000235:genetics*; D002871:Chromosome Banding; D025063:Chromosome Disorders; D004314:Down Syndrome / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007621:Karyotyping; D009850:Oman / Q000453:epidemiology