title: Chlamydial envelope components and pathogen-host cell interactions.
abstract: Few bacterial pathogens are as widespread in nature or as capable of eliciting such a diversity of disease syndromes as are the chlamydiae. As obligate intracellular organisms, they pose a special research challenge in defining the molecular components and mechanisms for productive growth within host cells and the overall progress of infection throughout host tissue. Although a comprehensive view of chlamydial envelope composition and respective functions in pathogenesis is far from complete, ongoing investigations continue to expose new and intriguing avenues for exploration.
authors.affiliation: UNC School of Medicine, Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27599-7290, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Raulston
mesh_terms: D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry* / Q000502:physiology; D002453:Cell Cycle; D002473:Cell Wall / Q000737:chemistry; D002689:Chlamydia / Q000737:chemistry* / Q000472:pathogenicity; D002690:Chlamydia Infections / Q000382:microbiology; D006790:Host-Parasite Interactions; D006801:Humans; D008070:Lipopolysaccharides / Q000378:metabolism; D051379:Mice; D008954:Models, Biological; D018272:Porins; D014774:Virulence
chemical_list: D001425:Bacterial Outer Membrane Proteins; D008070:Lipopolysaccharides; D018272:Porins; C071677:omp1 protein, Chlamydia trachomatis