[Richter syndrome: morphologic transformation with persistence of the same phenotype].
Richter's syndrome is termed as the occurrence of a high-grade lymphoma along with a chronic lymphocytic leukaemia. We report a patient diagnosed as having a CLL evolving into an immunoblastic lymphoma. In spite of this morphologic change, the same identical immunophenotype remained in both types of cells assessed, that is, CLL-type lymphocytes and immunoblastic and lymphoplasmocytoid cells. This event appears to favour the common clonal origin of these two entities.
Medina Pérez
A
A
Servicio de Hematología y Hemoterapia, Hospital Universitario Virgen del Rocío, Sevilla.
Ríos Herranz
E
E
Martín Noya
A
A
Prieto Fernández
J
J
Bodineau
C
C
de Blas
J
J
Rodríguez Fernández
J M
JM
D000368:Aged; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000276:immunology / Q000473:pathology; D008297:Male; D013577:Syndrome
Síndrome de Richter: transformación morfológica con persistencia del mismo fenotipo.