title: Intrauterine diagnosis and management of transient myeloproliferative disorder.
abstract: Transient myeloproliferative disorders can be associated with hydrops in Down syndrome fetuses. No cases of prenatal management of such a condition have been reported in the literature. We report a case of myeloproliferative disorder diagnosed by cordocentesis at 31 weeks in a Down syndrome fetus with pericardial effusion. A pericardiocentesis was performed at the first signs of hydrops and successfully improved fetal cardiac function, allowing for continuation of pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Ospedale S. Gerardo, Monza, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Strobelt
authors.forename: A
authors.initials: A
authors.lastname: Ghidini
authors.forename: A
authors.initials: A
authors.lastname: Locatelli
authors.forename: P
authors.initials: P
authors.lastname: Vergani
authors.forename: S
authors.initials: S
authors.lastname: Mariani
authors.forename: A
authors.initials: A
authors.lastname: Biondi
mesh_terms: D000328:Adult; D004314:Down Syndrome / Q000150:complications; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D015160:Hydrops Fetalis / Q000150:complications / Q000628:therapy; D007231:Infant, Newborn; D009196:Myeloproliferative Disorders / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D010490:Pericardial Effusion / Q000150:complications / Q000628:therapy; D011247:Pregnancy; D011296:Prenatal Diagnosis