title: Tissue- and development-specific expression of goat insulin-like growth factor-I (IGF-I) mRNAs.
abstract: We cloned four kinds of goat insulin-like growth factor-I (IGF-I) cDNAs. Each of them encodes the same mature IGF-I and different signal peptides. In this study, we analyzed expression of the four kinds of mRNAs in tissues in various developmental stages by a reverse transcriptase-polymerase chain reaction assay. The results suggest that their expression may be controlled by different promoters, the activities of which are tissue- and development-specific.
authors.affiliation: Department of Agricultural Chemistry, Kyoto University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Mikawa
authors.forename: G
authors.initials: G
authors.lastname: Yoshikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yamano
authors.forename: H
authors.initials: H
authors.lastname: Sakai
authors.forename: T
authors.initials: T
authors.lastname: Komano
authors.forename: Y
authors.initials: Y
authors.lastname: Hosoi
authors.forename: K
authors.initials: K
authors.lastname: Utsumi
mesh_terms: D000818:Animals; D001483:Base Sequence; D017931:DNA Primers; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006041:Goats; D007334:Insulin-Like Growth Factor I / Q000235:genetics*; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000235:genetics*
chemical_list: D017931:DNA Primers; D012333:RNA, Messenger; D007334:Insulin-Like Growth Factor I