title: Hematuria home screening: repeat testing results.
abstract: To determine at what interval screening should be repeated to detect bladder cancer before it becomes muscle invasive 856 men who had 14 negative daily home tests for hematuria with a chemical reagent strip 9 months previously performed repeat tests. Of these men 50 (5.8%) had at least 1 positive test during the second 14-day screening period and 38 were evaluated, 15 of whom (39.5%) had significant urological pathological conditions, including 8 with malignancies. Bladder cancer was noted in 7 men, with no tumor invading the muscularis propria. The finding of 7 bladder cancers in 856 men (0.82%) who had a negative test 9 months previously indicates that bladder cancer has a brief preclinical duration and that testing must be repeated at least annually for screening to detect bladder cancer consistently before invasion occurs.
authors.affiliation: Department of Surgery, University of Wisconsin, Madison, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: Messing
authors.forename: T B
authors.initials: TB
authors.lastname: Young
authors.forename: V B
authors.initials: VB
authors.lastname: Hunt
authors.forename: M A
authors.initials: MA
authors.lastname: Newton
authors.forename: L L
authors.initials: LL
authors.lastname: Bram
authors.forename: A
authors.initials: A
authors.lastname: Vaillancourt
authors.forename: W J
authors.initials: WJ
authors.lastname: Hisgen
authors.forename: E B
authors.initials: EB
authors.lastname: Greenberg
authors.forename: M E
authors.initials: ME
authors.lastname: Kuglitsch
authors.forename: J D
authors.initials: JD
authors.lastname: Wegenke
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000473:pathology; D003365:Costs and Cost Analysis; D005500:Follow-Up Studies; D006417:Hematuria / Q000175:diagnosis*; D006801:Humans; D007669:Kidney Calculi / Q000175:diagnosis; D008297:Male; D008403:Mass Screening / Q000191:economics; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology; D011934:Reagent Strips / Q000191:economics; D015203:Reproducibility of Results; D012648:Self Care; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000517:prevention & control*; D014552:Urinary Tract Infections / Q000175:diagnosis
chemical_list: D011934:Reagent Strips