Stereoselective microbial reduction of 2-keto-3-(N-benzoylamino)-3-phenyl propionic acid ethyl ester. Synthesis of taxol side-chain synthon.
Patel
R N
RN
Department of Microbial Technology, Bristol-Myers Squibb Pharmaceutical Research Institute, New Brunswick, New Jersey 08903, USA.
Banerjee
A
A
Howell
J M
JM
McNamee
C G
CG
Brzozowski
D
D
Nanduri
V
V
Thottathil
J K
JK
Szarka
L J
LJ
D001698:Biomedical Engineering; D010084:Oxidation-Reduction; D017239:Paclitaxel / Q000138:chemical synthesis*; D010666:Phenylpropionates / Q000737:chemistry*; D010843:Pichia / Q000378:metabolism; D011422:Propionates / Q000737:chemistry; D013237:Stereoisomerism
C094187:2-keto-3-(N-benzoylamino)-3-phenylpropionic acid ethyl ester; D010666:Phenylpropionates; D011422:Propionates; D017239:Paclitaxel