Childhood acquired epidermolysis bullosa.
We present the ninth case of epidermolysis bullosa acquisita (EBA) reported in children. As in most of the other childhood cases, the 7-year-old boy described herein had an acute, widespread, inflammatory vesiculobullous eruption with oral involvement. Indirect immunofluorescence on salt-split skin as well as Western immunoblot confirmed the diagnosis of EBA. The patient responded to combined prednisone and dapsone, and was maintained with dapsone alone.
Lacour
J P
JP
Department of Dermatology, Hôpital Pasteur, Nice, France.
Bernard
P
P
Rostain
G
G
Baechler-Sadoul
E
E
Pisani
A
A
Ortonne
J P
JP
D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000974:Antibodies, Antinuclear; D000962:Antimalarials / Q000627:therapeutic use; D015153:Blotting, Western; D002648:Child; D002675:Child, Preschool; D003622:Dapsone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D016107:Epidermolysis Bullosa Acquisita / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000302:isolation & purification; D007075:Immunoglobulin M / Q000302:isolation & purification; D007223:Infant; D008297:Male; D012867:Skin / Q000737:chemistry
D000305:Adrenal Cortex Hormones; D000974:Antibodies, Antinuclear; D000962:Antimalarials; D007070:Immunoglobulin A; D007075:Immunoglobulin M; D003622:Dapsone