Intrauterine diagnosis and management of transient myeloproliferative disorder.
Transient myeloproliferative disorders can be associated with hydrops in Down syndrome fetuses. No cases of prenatal management of such a condition have been reported in the literature. We report a case of myeloproliferative disorder diagnosed by cordocentesis at 31 weeks in a Down syndrome fetus with pericardial effusion. A pericardiocentesis was performed at the first signs of hydrops and successfully improved fetal cardiac function, allowing for continuation of pregnancy.
Strobelt
N
N
Department of Obstetrics and Gynecology, Ospedale S. Gerardo, Monza, Italy.
Ghidini
A
A
Locatelli
A
A
Vergani
P
P
Mariani
S
S
Biondi
A
A
D000328:Adult; D004314:Down Syndrome / Q000150:complications; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D015160:Hydrops Fetalis / Q000150:complications / Q000628:therapy; D007231:Infant, Newborn; D009196:Myeloproliferative Disorders / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D010490:Pericardial Effusion / Q000150:complications / Q000628:therapy; D011247:Pregnancy; D011296:Prenatal Diagnosis