title: [Cytokines in immunopathogenesis of pulmonary tuberculosis].
abstract: Production of IL-1, IL-2, gamma-interferon and PNO was measured in 46 patients with various forms of pulmonary tuberculosis. Cytokins quantitation was conducted biologically, using radioimmunoassay and enzyme immunoassay in supernatants of cellular structures (blood lymphocytes). There were high levels of IL-1 and PNO, reduced production of IL-2 and gamma-IFN by stimulated blood mononuclears. In effective chemotherapy (3-4 months) production of IL-1 tented to a decline, while that of IL-2 and gamma-IFN went up.
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Gergert
authors.forename: G A
authors.initials: GA
authors.lastname: Kosmiadi
authors.forename: Z P
authors.initials: ZP
authors.lastname: Abramova
mesh_terms: D000328:Adult; D000818:Animals; D002478:Cells, Cultured; D016207:Cytokines / Q000097:blood*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007371:Interferon-gamma / Q000097:blood; D007375:Interleukin-1 / Q000097:blood; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology; D011863:Radioimmunoassay; D014397:Tuberculosis, Pulmonary / Q000209:etiology / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
chemical_list: D016207:Cytokines; D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma
vernacular_title: Tsitokiny v immunopatogeneze tuberkuleza legkikh.