Selenium and magnesium status in fibromyalgia.
Muscle pain has been associated with magnesium (Mg) and selenium (Se) deficiency: magnesium and selenium status were investigated in fibromyalgia (FM). Erythrocyte (E), leucocyte (L) and serum (S) magnesium, serum selenium and zinc, and vitamin B1, B2, A or E status were assessed in 22 patients with fibromyalgia and in 23 age-matched healthy controls. LMg is significantly increased (P < 0.05) and EMg slightly decreased in fibromyalgia. These magnesium abnormalities are associated with previously-reported impairment of thiamin metabolism. Antioxidant status (as well as plasma malondialdehyde) is unchanged in fibromyalgia and serum selenium levels, slightly but not significantly correlated with serum magnesium, is normal.
Eisinger
J
J
Centre Hospitalier de Toulon, France.
Plantamura
A
A
Marie
P A
PA
Ayavou
T
T
D000328:Adult; D004912:Erythrocytes / Q000737:chemistry; D005260:Female; D005356:Fibromyalgia / Q000097:blood*; D005980:Glutathione Reductase / Q000097:blood; D006801:Humans; D007962:Leukocytes / Q000737:chemistry; D008274:Magnesium / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D012189:Retrospective Studies; D012643:Selenium / Q000097:blood*; D014815:Vitamins / Q000097:blood; D015032:Zinc / Q000097:blood
D014815:Vitamins; D008315:Malondialdehyde; D005980:Glutathione Reductase; D012643:Selenium; D008274:Magnesium; D015032:Zinc