title: Prolonged brainstem auditory evoked potential latencies in tropical pancreatic diabetics with normal hearing.
abstract: Twenty patients with Tropical Pancreatic Diabetes (TPD) were evaluated by Brainstem Auditory Evoked Potentials (BAEP) in order to detect any possible subclinical involvement of auditory pathways. The latencies of BAEP Wave III (p < 0.009) and V (p < 0.47) as well as the Interpeak Latencies I-III (p < 0.002), and I-V (p < 0.019) were significantly prolonged in patients with TPD when compared to age and sex matched healthy volunteers. There was correlation between the abnormalities of BAEP and duration of diabetes (p < 0.006), male sex of patients (p < 0.05), and the presence of retinopathy (p < 0.003) and nephropathy (p < 0.38). There was no significant correlation with the age of the patients, type of treatment, blood sugar levels and presence of peripheral neuropathy. These changes suggest a subclinical involvement of the auditory pathways in TDP patients.
authors.affiliation: Department of Neurology, Sree Chitra Tirunal Institute for Medical Science and Technology, Thiruvananthapuram, India.
authors.forename: M
authors.initials: M
authors.lastname: Alexander
authors.forename: S V
authors.initials: SV
authors.lastname: Thomas
authors.forename: P K
authors.initials: PK
authors.lastname: Mohan
authors.forename: M
authors.initials: M
authors.lastname: Narendranathan
mesh_terms: D000328:Adult; D001933:Brain Stem / Q000503:physiopathology; D003906:Developing Countries; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000503:physiopathology*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D002365:Manihot / Q000009:adverse effects*; D010182:Pancreatic Diseases / Q000503:physiopathology*; D011502:Protein-Energy Malnutrition / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology