Primary malignant lymphoma of the liver associated with cirrhosis induced by hepatitis C viral infection.
We present a case of primary malignant lymphoma of the liver of B cell origin with cirrhosis induced by hepatitis C viral infection. A 75-year-old Japanese woman with chronic liver dysfunction was admitted for hepatic tumors. The tumors were hypoechoic on ultrasonography and hypodense on computed tomography. Antibody to hepatitis C virus was positive. Ultrasonically guided biopsy was performed, and we diagnosed hepatic lymphoma with cirrhosis induced by hepatitis C virus clinically and immunohistochemically. This case may be the first report of the association of these two diseases, and may provide additional evidence of a predisposition to malignancy in cirrhosis.
Morita
K
K
Department of Internal Medicine, Koseiren Kamo Hospital, Aichi.
Hoshino
H
H
Imada
J
J
Yoshida
N
N
Nishimura
D
D
Katada
N
N
Sano
H
H
Kato
K
K
D000368:Aged; D017809:Fatal Outcome; D005260:Female; D016174:Hepacivirus; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000628:therapy / Q000821:virology; D008113:Liver Neoplasms / Q000150:complications* / Q000628:therapy / Q000821:virology; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000628:therapy / Q000821:virology