title: Pattern of malignant bone tumour in northern areas of Pakistan.
abstract: A review of 280 primary malignant bone tumours diagnosed during 1984-1988 is presented. These constituted 3.14% of all malignant tumours. Male to female ratio was 2.3:1. Majority of these patients presented with rapidly growing mass, pain and deformity. Histologically, osteosarcoma was the most frequent (36.4%) primary malignant tumour. Male to female ratio was 3.31:1. More than 49% of these cases were in their second decade of life. In females the greatest frequency was in 10-15 years and in males 16-20 years age groups. Femur was the most frequent site. Other common malignant bone tumours included chondrosarcoma (22.1%), plasma cell myeloma (15.0%) and Ewings's sarcoma (8.6%). Miscellaneous cases of fibrosarcoma, chrodoma, adamentinoma and ameloblastoma were also seen. This study outlines the frequency, symptomatology and histological pattern of various malignant bone tumours in northern areas of Pakistan.
authors.affiliation: Armed Forces Institute of Pathology, Rawalpindi.
authors.forename: M
authors.initials: M
authors.lastname: Ahmad
authors.forename: A
authors.initials: A
authors.lastname: Ghani
authors.forename: A
authors.initials: A
authors.lastname: Mansoor
authors.forename: A H
authors.initials: AH
authors.lastname: Khan
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000453:epidemiology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000453:epidemiology; D010154:Pakistan / Q000453:epidemiology; D017678:Sex Distribution