title: Characterization of an antithrombotic peptide from kappa-casein in newborn plasma after milk ingestion.
abstract: Bovine and human kappa-caseinoglycopeptides, two antithrombotic peptides derived from the corresponding kappa-caseins, were detected in physiologically active concentrations in the plasma of 5-d-old newborn infants after ingestion of cow's-milk-based formula or human milk respectively. It is suggested that these two bioactive peptides are released from milk proteins during digestion.
authors.affiliation: CNRS URA 1188, Laboratoire des Protéines, Université de Paris V, France.
authors.forename: B
authors.initials: B
authors.lastname: Chabance
authors.forename: P
authors.initials: P
authors.lastname: Jollès
authors.forename: C
authors.initials: C
authors.lastname: Izquierdo
authors.forename: E
authors.initials: E
authors.lastname: Mazoyer
authors.forename: C
authors.initials: C
authors.lastname: Francoual
authors.forename: L
authors.initials: L
authors.lastname: Drouet
authors.forename: A M
authors.initials: AM
authors.lastname: Fiat
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002364:Caseins / Q000097:blood* / Q000378:metabolism*; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D004797:Enzyme-Linked Immunosorbent Assay; D005343:Fibrinolytic Agents / Q000097:blood*; D006020:Glycopeptides / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D008892:Milk / Q000737:chemistry / Q000378:metabolism*; D008894:Milk Proteins / Q000032:analysis; D008895:Milk, Human / Q000737:chemistry / Q000378:metabolism*; D008969:Molecular Sequence Data
chemical_list: D002364:Caseins; D005343:Fibrinolytic Agents; D006020:Glycopeptides; D008894:Milk Proteins; C094310:kappa-caseinoglycopeptide