title: 111In-octreotide uptake in granulomatous and tumor lesions in a patient with small-cell lung cancer.
abstract: A case of a patient with small cell lung cancer and right submandibular node enlargement due to granulomatous lymphadenitis is presented. Diagnostic procedures included: biopsy of the cervical node, transmission computed tomography of the chest, bronchoscopic examination and biopsy of the pulmonary lesion. The patient underwent 111In-octreotide scintigraphy (whole body and single photon emission tomography) which revealed both lesions. We conclude that granulomatous lesions are to be considered as a possible cause of false positive results, when octreotide scintigraphy is used to evaluate distant metastases in patients with known cancer.
authors.affiliation: Nuclear Medicine Division, National Cancer Institute, Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Crippa
authors.forename: E
authors.initials: E
authors.lastname: Bombardieri
authors.forename: A
authors.initials: A
authors.lastname: Chiti
authors.forename: E
authors.initials: E
authors.lastname: Soresi
authors.forename: R
authors.initials: R
authors.lastname: Boffi
authors.forename: G L
authors.initials: GL
authors.lastname: Buraggi
mesh_terms: D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging*; D006801:Humans; D007205:Indium Radioisotopes; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008230:Lymphomatoid Granulomatosis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000031:analogs & derivatives*; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D015899:Tomography, Emission-Computed, Single-Photon; D014388:Tuberculosis, Lymph Node / Q000000981:diagnostic imaging*
chemical_list: D007205:Indium Radioisotopes; C094279:indium-111-octreotide; C071632:SDZ 215-811; D004369:Pentetic Acid; D015282:Octreotide