title: GABAergic neuronal circuits in the cerebellum of the dogfish Scyliorhinus canicula (Elasmobranchs): an immunocytochemical study.
abstract: The presence of GABAergic cells and fibres in the corpus cerebelli and auricles of a dogfish, Scyliorhinus canicula, was studied with immunocytochemistry. In both locations, two types of GABA-immunoreactive (GABA-ir) neurons were observed: stellate cells in the molecular layer and Golgi cells in the granular layer. Stellate cell axons gave rise to numerous GABA-ir boutons distributed throughout the molecular layer and a smaller number of boutons which contacted Purkinje cell perikarya. No GABA-ir baskets around Purkinje cells were observed. Golgi cells of the granular layer gave rise to numerous GABA-ir boutons which were located around cerebellar glomeruli. Purkinje cell perikarya and their axon terminals in the cerebellar nucleus were not GABA-immunoreactive. These findings are discussed in terms of the phylogeny of cerebellar circuits.
authors.affiliation: Departamento de Biología Fundamental, Universidad de Vigo, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Alvarez-Otero
authors.forename: S E
authors.initials: SE
authors.lastname: Pérez
authors.forename: M A
authors.initials: MA
authors.lastname: Rodríguez
authors.forename: F
authors.initials: F
authors.lastname: Adrio
authors.forename: R
authors.initials: R
authors.lastname: Anadón
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D004284:Dogfish / Q000502:physiology*; D007150:Immunohistochemistry; D009434:Neural Pathways / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
chemical_list: D005680:gamma-Aminobutyric Acid