title: Progress in Drosophila genome manipulation.
abstract: The introduction of cloned and manipulated genetic material into the germline of an experimental organism is one of the most powerful tools of modern biology. In the case of the fruit fly, Drosophila melanogaster, there is also an unparalleled range of sophisticated genetic tools to facilitate subsequent analysis. In consequence, Drosophila remains a most favourable model organism for the dissection of gene structure and function in vivo. In this review we look at some of the achievements to date in Drosophila genome manipulation, and at what may be possible in the near future.
authors.affiliation: Department of Genetics, University of Glasgow, UK.
authors.forename: L W
authors.initials: LW
authors.lastname: Sentry
authors.forename: K
authors.initials: K
authors.lastname: Kaiser
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000235:genetics*; D004742:Enhancer Elements, Genetic; D016678:Genome; D018095:Germ-Line Mutation; D011995:Recombination, Genetic; D014170:Transformation, Genetic
chemical_list: D004251:DNA Transposable Elements