Von Hippel-Lindau disease with multiple spinal cord hemangioblastomas, syringomyelia and pheochromocytoma.
A 31-year-old blind man presented with numbness and weakness in the left hand, and elevated blood pressure. Multiple hemangioblastomas in the spinal cord associated with syringomyelia were well demonstrated by gadolinium-enhanced magnetic resonance imaging (MRI). He also had pheochromocytoma in the right adrenal gland, which was disclosed by abdominal computed tomography, MRI and 131I-metaiodobenzylguanidine scintigraphy. MRI screening should be considered for patients with von Hippel-Lindau gene to detect the multiple lesions in this disease.
Furusu
H
H
Department of Internal Medicine, Japanese Red Cross Nagasaki Atomic Bomb Hospital, Nagasaki.
Matsuo
H
H
Nakao
K
K
Ueda
Y
Y
Aoi
W
W
D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D000328:Adult; D018325:Hemangioblastoma / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D010673:Pheochromocytoma / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013120:Spinal Cord Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013595:Syringomyelia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D014057:Tomography, X-Ray Computed; D006623:von Hippel-Lindau Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy