title: The morphological properties of the blood thrombocytes in bronchial asthma patients before and after thrombocytapheresis.
abstract: Morphological characteristics of platelets were assessed electron microscopically in 15 patients with atopic and aspirin bronchial asthma (BA) before and after thrombocytapheresis (TA). All the patients had a definite shift of platelet subpopulations to greater percentage of spherical forms as well as defects in cell ultrastructure. This makes evident platelet activation in patients with BA aggravation. TA entails a positive trend to normalization of platelet subpopulations and cytoskeleton. The ability to normalize platelet morphofunctional status determines its clinical effectiveness in bronchial asthma.
authors.forename: A R
authors.initials: AR
authors.lastname: Tatarskiĭ
authors.forename: K M
authors.initials: KM
authors.lastname: Alieva
authors.forename: L I
authors.initials: LI
authors.lastname: Buriachkovskaia
authors.forename: L E
authors.initials: LE
authors.lastname: Petrova
authors.forename: E V
authors.initials: EV
authors.lastname: Bobkov
authors.forename: A G
authors.initials: AG
authors.lastname: Chuchalin
mesh_terms: D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000097:blood* / Q000628:therapy; D001792:Blood Platelets / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010976:Platelet Count; D010983:Plateletpheresis
vernacular_title: Morfologicheskie svoĭstva trombotsitov krovi u bol'nykh bronkhial'noĭ astmoĭ do i posle trombotsitafereza.