title: Sclerosing osteomyelitis and Actinomyces naeslundii infection of surrounding tissues.
abstract: We present the case of a young man with chronic Actinomyces naeslundii infection in the lower leg who underwent a below-the-knee amputation after unsuccessful attempts at diagnosing and eradicating the infection. Actinomycetic organisms from environmental sources can engender a dense fibrotic tissue response without fistulae. Such a response led to a painful, sclerosing, nonsuppurative infection of the bone and surrounding tissues in our patient. This clinical picture, at least the bony and periosteal reaction, was compatible with Garrè's osteomyelitis.
authors.affiliation: Division of Infectious Diseases, Baptist Medical Center, Jacksonville, Florida, USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Vandevelde
authors.forename: S G
authors.initials: SG
authors.lastname: Jenkins
authors.forename: P R
authors.initials: PR
authors.lastname: Hardy
mesh_terms: D000190:Actinomyces / Q000302:isolation & purification; D000196:Actinomycosis / Q000150:complications*; D000328:Adult; D002908:Chronic Disease; D005528:Foot / Q000473:pathology*; D005534:Foot Diseases / Q000382:microbiology*; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000382:microbiology*; D012598:Sclerosis