Nephroblastoma and end-stage renal failure with bilateral cystic kidneys.
A child of 10 years 5 months presenting with chronic renal failure had bilateral cystic kidneys. Biopsy of a right lower-pole solid mass revealed nephroblastoma. At bilateral nephrectomy, both kidneys were both replaced by variable-sized cysts with a unifocal nephroblastoma on the right. Renal failure with nephroblastoma is uncommon and is usually either a manifestation of the Drash syndrome or a complication of chemotherapy. The need to assess both kidneys in a child with any other renal abnormality in addition to a renal mass should always be considered.
Craver
R D
RD
Department of Pathology, Louisiana State University School of Medicine, New Orleans 70112-1393, USA.
Correa
H
H
Hollowell
J G
JG
Warrier
R P
RP
D002648:Child; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D007680:Kidney Neoplasms / Q000150:complications*; D008297:Male; D007690:Polycystic Kidney Diseases / Q000150:complications*; D009396:Wilms Tumor / Q000150:complications*