Exotoxin profiles of Campylobacters isolated in Malaysia.
Approximately 57% of clinical and 33% of poultry isolates examined produced a cytotoxin. Cytotoxic activity was detected in 25 (50%) isolates of Campylobacter of which 12 were isolated from bloody diarrhea and 9 from watery stools. The cytotoxin titers were low, ranging from 2 to 16. The crude filtrates from 50 Campylobacter isolates showed no cytotoxic effect in Vero cells, no fluid accumulation in suckling mice and no hemolytic activity.
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Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Devi
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Puthucheary
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Kautner
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D000818:Animals; D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000633:toxicity; D002167:Campylobacter / Q000378:metabolism* / Q000472:pathogenicity; D002478:Cells, Cultured; D002522:Chlorocebus aethiops; D003603:Cytotoxins / Q000096:biosynthesis* / Q000633:toxicity; D003967:Diarrhea / Q000382:microbiology; D006461:Hemolysis; D006801:Humans; D008296:Malaysia; D051379:Mice; D014709:Vero Cells
D001427:Bacterial Toxins; D003603:Cytotoxins