[Lymphohistiocytic infiltration of endometrial adenocarcinoma].
Mononuclear cells adjacent to endometrial adenocarcinoma were evaluated in 8 biopsies by the immunoperoxidase technique. Between benign and malignant tissue a remarkable infiltration of CD45+, CD3+, CD4+, CD8+, and CD14+ cells could be observed. B cells (CD19) and NK cells (CD57) were rare. Tumor-infiltrating lymphocytes were only sparsely distributed. The findings suggest a cellular, yet ineffective, immune reaction of the host against the tumor at the borderline between benign and malignant tissue.
Böhme
M
M
Hauptabteilung für Gynäkologie der Klinik St. Marienstift.
Löttge
M
M
Schmidt
D
D
Röse
I
I
Weise
W
W
Morenz
J
J
D000230:Adenocarcinoma / Q000276:immunology / Q000473:pathology*; D000231:Adenocarcinoma, Papillary / Q000276:immunology / Q000473:pathology; D015703:Antigens, CD / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology*; D001706:Biopsy; D018196:Carcinoma, Adenosquamous / Q000276:immunology / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000276:immunology / Q000473:pathology; D016889:Endometrial Neoplasms / Q000276:immunology / Q000473:pathology*; D004717:Endometrium / Q000276:immunology / Q000473:pathology; D005260:Female; D006644:Histiocytes / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D018655:Lymphocyte Count; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology*
D015703:Antigens, CD
Lymphohistiozytäre Infiltration des endometrialen Adenokarzinoms.