title: [Feasibility study: concurrent 13-cis-retinoic acid, alfa-2a interferon and radiotherapy in the treatment of 23 patients with advanced cervix uteri epidermoid carcinoma].
abstract: The important therapeutic activity of 13-cRA and IFN-alpha-2a in carcinoma of squamous cells, cervical, without previous treatment, is confirmed. An unexpected result was the early toxicity of the biologic agents on the colon mucosa when they are combined with radiotherapy.
authors.affiliation: Servicio de Medicina Interna del Hospital Civil de Guadalajara y Torre de Especialidades.
authors.forename: M
authors.initials: M
authors.lastname: Paredes Espinoza
authors.forename: F
authors.initials: F
authors.lastname: Delgadillo Madrueño
authors.forename: P
authors.initials: P
authors.lastname: Paredes Casillas
authors.forename: J J
authors.initials: JJ
authors.lastname: Delgadillo Hernández
authors.forename: M M
authors.initials: MM
authors.lastname: Ayala Castellanos
authors.forename: V
authors.initials: V
authors.lastname: Alvarez Márquez
authors.forename: M A
authors.initials: MA
authors.lastname: Buenrostro Ahued
authors.forename: G
authors.initials: G
authors.lastname: Arias Castro
mesh_terms: D000328:Adult; D000368:Aged; D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy*; D002588:Cesium Radioisotopes / Q000008:administration & dosage; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003106:Colon / Q000187:drug effects / Q000528:radiation effects; D003131:Combined Modality Therapy; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use* / Q000633:toxicity; D007413:Intestinal Mucosa / Q000187:drug effects / Q000528:radiation effects; D015474:Isotretinoin / Q000627:therapeutic use* / Q000633:toxicity; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D011994:Recombinant Proteins; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*
chemical_list: D002588:Cesium Radioisotopes; D003037:Cobalt Radioisotopes; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D015474:Isotretinoin
vernacular_title: Estudio de factibilidad: ácido 13-cisretinoico, interferón alpha-2a y radioterapia concurrentes en el tratamiento de 23 pacientes con carcinoma epidermoide cervicouterino avanzado.