title: Recrudescence and relapse of meningococcal meningitis and septicaemia.
abstract: Three cases of recrudescence and relapse of Neisseria meningitidis group B meningitis and septicaemia are reported. The recrudescence and relapses could not be explained by infectious foci, increased bacterial penicillin resistance or immunological defects. As a supplement to antibiotic treatment, all three patients received corticosteroids for the initial 2 days of treatment, and this may have contributed to the unusual course of the disease in our patient.
authors.affiliation: Department of Paediatrics, Viborg County Hospital, Denmark.
authors.forename: P E
authors.initials: PE
authors.lastname: Nielsen
authors.forename: T
authors.initials: T
authors.lastname: Thelle
authors.forename: M
authors.initials: M
authors.lastname: Tvede
mesh_terms: D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy*; D002675:Child, Preschool; D002701:Chloramphenicol / Q000008:administration & dosage / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage / Q000627:therapeutic use; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D008585:Meningitis, Meningococcal / Q000188:drug therapy*; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D010400:Penicillin G / Q000008:administration & dosage / Q000627:therapeutic use; D010404:Penicillin V / Q000008:administration & dosage / Q000627:therapeutic use; D012008:Recurrence; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D002701:Chloramphenicol; D010400:Penicillin G; D012293:Rifampin; D006854:Hydrocortisone; D008775:Methylprednisolone; D010404:Penicillin V