title: Assignment of the gene (GLCLC) that encodes the heavy subunit of gamma-glutamylcysteine synthetase to human chromosome 6.
abstract: Assignment of the human gene (GLCLC) that encodes the heavy or catalytic subunit of gamma-glutamylcysteine synthetase (glutamate-cysteine ligase; EC 6.3.2.2) to human chromosome 6 was accomplished by hybridization to Southern blotted somatic cell hybrid DNA. This assignment was confirmed by PCR from somatic cell hybrid DNAs.
authors.affiliation: Center for Radiation Oncology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
authors.forename: E
authors.initials: E
authors.lastname: Sierra-Rivera
authors.forename: M L
authors.initials: ML
authors.lastname: Summar
authors.forename: M
authors.initials: M
authors.lastname: Dasouki
authors.forename: M R
authors.initials: MR
authors.lastname: Krishnamani
authors.forename: J A
authors.initials: JA
authors.lastname: Phillips
authors.forename: M L
authors.initials: ML
authors.lastname: Freeman
mesh_terms: D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002896:Chromosomes, Human, Pair 6; D004247:DNA / Q000032:analysis; D017931:DNA Primers; D018076:DNA, Complementary; D005721:Glutamate-Cysteine Ligase / Q000235:genetics*; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D046911:Macromolecular Substances; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
chemical_list: D017931:DNA Primers; D018076:DNA, Complementary; D046911:Macromolecular Substances; D004247:DNA; D005721:Glutamate-Cysteine Ligase