[The determination of specific Pseudomonas aeruginosa antitoxins in commercial preparations of human immunoglobulin].
The comparative study of the activity of P. aeruginosa specific antitoxins in 134 lots of commercial preparations of human immunoglobulin in parallel mouse experiments on the neutralization of the lethal effect of exotoxin and in ELISA made it possible to establish a high degree of correlation between their results and the possibility of using immunochemical assays instead of biological tests in the large-scale production of anti-P. aeruginosa immunoglobulin.
Vaneeva
N P
NP
Ianishevskaia
M N
MN
Aleksandrova
T N
TN
Ianshina
N L
NL
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D000918:Antibody Specificity; D000992:Antitoxins / Q000032:analysis*; D001427:Bacterial Toxins / Q000037:antagonists & inhibitors*; D001681:Biological Assay / Q000379:methods; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005069:Evaluation Studies as Topic; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D051379:Mice; D011550:Pseudomonas aeruginosa / Q000276:immunology
D000907:Antibodies, Bacterial; D000992:Antitoxins; D001427:Bacterial Toxins; D007136:Immunoglobulins
Opredelenie spetsificheskikh antitoksionv Pseudomonas aeruginosa v kommercheskikh preparatakh immunoglobulina cheloveka.