title: Antioxidative activity of hop bitter acids and their analogues.
abstract: Hop bitter acids, humulones (1) and lupulones (2), were shown to have potent DPPH radical scavenging activity (RSA) and lipid peroxidation inhibitory activity (LIA). Furthermore, 5-acetyl lupulones (3) and 4-methyl lupulones (4) had more potent LIA than native lupulones but no RSA. This result indicates that the beta, beta'-triketone moiety of the lupulones has LIA.
authors.affiliation: Central Research Laboratories, Asahi Breweries Ltd., Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tagashira
authors.forename: M
authors.initials: M
authors.lastname: Watanabe
authors.forename: N
authors.initials: N
authors.lastname: Uemitsu
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D053138:Cyclohexenes; D016166:Free Radical Scavengers; D010944:Plants / Q000737:chemistry*; D013729:Terpenes / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D053138:Cyclohexenes; D016166:Free Radical Scavengers; D013729:Terpenes; C008299:lupulon; C007966:humulon