Expression of messenger RNA for somatostatin receptor subtype 4 in adult rat brain.
The distribution and cellular localisation of somatostatin receptor subtype 4 (SSTR4) was investigated in the adult rat brain using the technique of in situ hybridisation with subtype specific oligonucleotide probes. Somatostatin receptor subtype 4 was found mainly in the hippocampus CA1 > CA2 > CA3 pyramidal cells and in the pyramidal cells in layers (IV-VI) of the cerebral cortex. Reverse transcription-PCR with SSTR4 specific primers confirmed the tissue distribution revealed by in situ hybridisation.
Harrington
K A
KA
Department of Neurobiology, Babraham Institute, Cambridge, UK.
Schindler
M
M
Humphrey
P P
PP
Emson
P C
PC
D000818:Animals; D002529:Cerebellar Nuclei / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism*; D015870:Gene Expression; D006624:Hippocampus / Q000378:metabolism; D017403:In Situ Hybridization; D016133:Polymerase Chain Reaction; D017966:Pyramidal Cells / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D051381:Rats; D017481:Receptors, Somatostatin / Q000235:genetics / Q000378:metabolism*
D012333:RNA, Messenger; D017481:Receptors, Somatostatin