Study on preventive and curative effects of liu wei di huang tang on tumors.
Liu Wei Di Huang Tang (LWDHT), a Chinese prescription for strengthening the body resistance, restoring the normal functions of the body to consolidate the constitution, and nourishing and invigorating the kidney yin, has been used to prevent and treat severe hyperplasia of esophageal epithelium for many years. The results of this experiment show that LWDHT can increase markedly the number of lymphocytes, mainly T lymphocytes, in tumor-bearing mice. Free-flow electrophoresis shows that in tumor-bearing mice the electrophoretic characteristics of T lymphocytes are changed, i.e., reduction of the number of T lymphocytes with a higher electrophoretic rate, but LWDHT can alleviate this disorder. Study on the cell membrane fluidity of carcinoma cells in EAC mice demonstrates that LWDHT can decrease the cell membrane fluidity, suggesting that it can inhibit division of carcinoma cells.
Cai
B
B
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine.
Jiang
T
T
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy* / Q000276:immunology; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D008297:Male; D051379:Mice; D013601:T-Lymphocytes / Q000187:drug effects*
D004365:Drugs, Chinese Herbal