An important role for intestinally derived T cells in respiratory defence.
Margaret Dunkley, Reinhard Pabst and Allan Cripps discuss the role of intestinally derived T cells in protecting the lung against Gram-negative bacterial infection. They describe the factors directing T-cell migration from gut-associated lymphoid tissue to lung, and focus on the role of T cells and T-cell-derived cytokines in bacterial clearance from the lung.
Dunkley
M
M
Faculty of Medicine and Health Science, University of Newcastle, Australia.
Pabst
R
R
Cripps
A
A
D006090:Gram-Negative Bacteria / Q000276:immunology* / Q000472:pathogenicity; D016905:Gram-Negative Bacterial Infections / Q000276:immunology*; D007109:Immunity; D007422:Intestines / Q000276:immunology*; D008168:Lung / Q000276:immunology* / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*