Toward reducing risks and costs of egg donation: a preliminary report.
OBJECTIVE
To use clomiphene citrate for ovarian stimulation of egg donors as a means of reducing the risk, discomfort, and inconvenience for egg donors and reducing costs for recipients.


METHODS
Prospective nonrandomized clinical study.


METHODS
Private reproductive center.


METHODS
Egg donation recipients and their anonymous donors.


METHODS
Clomiphene citrate was administered to egg donors rather than a GnRH agonist and gonadotropins before oocyte retrieval.


METHODS
Pregnancy.


RESULTS
Eleven oocyte retrievals were performed and conception occurred in four cycles, three of which delivered.


CONCLUSIONS
Clomiphene citrate appears to be a reasonable less expensive method of ovarian stimulation for egg donation in normospermic males and appears more acceptable to potential donors.
Seibel
M M
MM
Faulkner Centre for Reproductive Medicine, Boston, Massachusetts 02130, USA.
D000328:Adult; D002996:Clomiphene / Q000494:pharmacology*; D003365:Costs and Cost Analysis; D005260:Female; D005306:Fertilization; D006801:Humans; D018587:Oocyte Donation / Q000009:adverse effects* / Q000191:economics*; D010053:Ovary / Q000187:drug effects*; D011446:Prospective Studies; D012307:Risk Factors
D002996:Clomiphene