title: [Cardiovascular toxicity of anticancer chemotherapy: 5 cases treated in intensive care].
abstract: During a five-months period, 5 cases of cardiovascular toxicity related to chemotherapy were observed. Various hypotheses are discussed to explain the pathogenicity of this type of toxicity. Cardiovascular risk factors may favor this toxicity. In the presence of known cardiovascular risk factors, the choice of a less toxic regimen is desirable and, if this is not possible, the patient should be treated with continuous monitoring of the vital parameters.
authors.affiliation: Service de Médecine et Laboratoire d'Investigation Clinique H. J. Tagnon, Institut Bordet, Bruxelles.
authors.forename: C
authors.initials: C
authors.lastname: Sotiriou
authors.forename: J P
authors.initials: JP
authors.lastname: Sculier
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002561:Cerebrovascular Disorders / Q000139:chemically induced*; D002945:Cisplatin / Q000009:adverse effects; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000139:chemically induced*; D012307:Risk Factors; D012770:Shock, Cardiogenic / Q000139:chemically induced
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin; D005472:Fluorouracil; D007069:Ifosfamide
vernacular_title: Toxicité cardiovasculaire de la chimiothérapie anticancéreuse: cinq observations réalisées en soins intensifs.