title: Detection by immunoblot assay of antibodies to Taenia solium cysticerci in sera from residents of rural communities and from epileptic patients in Bali, Indonesia.
abstract: Several studies from Bali have indicated the presence of Taenia solium. Relatively little has been reported, however, implicating human exposure to this parasite on Bali based upon the prevalence of anti-T. solium antibodies in asymptomatic and epileptic individuals. This study was conducted to determine by immunoblot assay and ELISA the frequency of anti-cysticercus antibodies in two groups of Balinese. Among 746 residents of four ecologic zones, 94 (13%) were positive by immunoblot. Of 74 epileptic patients from throughout the island, 10 (14%) were positive by immunoblot and 8 (11%) by ELISA; however, only 4 (22%) of the 18 sera positive in either test were positive in both assays. The previously defined high specificity and sensitivity of immunoblot indicates that T. solium cysticercosis is well established in Bali and that a significant amount of epilepsy may be due to neurocysticercosis.
authors.affiliation: Department of Medical Microbiology School of Medicine, University of California, Davis 95616, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Theis
authors.forename: R S
authors.initials: RS
authors.lastname: Goldsmith
authors.forename: A
authors.initials: A
authors.lastname: Flisser
authors.forename: J
authors.initials: J
authors.lastname: Koss
authors.forename: C
authors.initials: C
authors.lastname: Chioino
authors.forename: A
authors.initials: A
authors.lastname: Plancarte
authors.forename: A
authors.initials: A
authors.lastname: Segura
authors.forename: D
authors.initials: D
authors.lastname: Widjana
authors.forename: P
authors.initials: P
authors.lastname: Sutisna
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis*; D002648:Child; D003551:Cysticercosis / Q000150:complications* / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D004827:Epilepsy / Q000209:etiology*; D005260:Female; D006801:Humans; D015151:Immunoblotting; D007214:Indonesia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012423:Rural Health; D012680:Sensitivity and Specificity; D016036:Seroepidemiologic Studies; D013621:Taenia / Q000276:immunology*
chemical_list: D000909:Antibodies, Helminth