title: [The effect of neuroleptics on blood proteins during development of toxic cerebral edema-brain swelling].
abstract: Simulation of toxic brain edema-swelling allowed one to analyze the dynamics of blood protein alteration in presence of various neuroleptics. Alterations in blood protein fractions correlated with dynamics of nervous tissue impairments. All the drugs studied exhibited similar antiswelling action involving the gamma-globulin sub-system activation. At the same time, the neuroleptics with activating and depriving effects demonstrated an oppositely directed influence on blood albumins.
authors.forename: I A
authors.initials: IA
authors.lastname: Platonov
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000187:drug effects*; D001929:Brain Edema / Q000139:chemically induced / Q000503:physiopathology*; D005042:Etimizol / Q000494:pharmacology*; D008728:Methotrimeprazine / Q000494:pharmacology*; D011395:Promazine / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001798:Blood Proteins; D008728:Methotrimeprazine; D005042:Etimizol; D011395:Promazine
vernacular_title: Vliianie neĭroleptikov na sistemu belkov krovi pri formirovanii toksicheskogo oteka-nabukhaniia golovnogo mozga.