[Flow cytometry used to distinguish between complete and partial hydatidiform moles].
The nuclear ploidy of 14 placentas was determined by flow cytometry. All histologically classified complete moles (4 cases), hydropic villi (4 cases) and control placentas (3 cases) were diploid; whereas two of three histologically classified partial moles were triploid. The remaining case classified as partial mole was diploid, most likely a complete mole. It was concluded that DNA flow cytometric analysis offers an informative supplement to the histological interpretation of hydropic placentas.
Guo
L
L
PUMC Hospital, CAMS, Beijing.
Tang
M
M
Ye
S
S
Zhu
L
L
D004273:DNA, Neoplasm / Q000235:genetics; D003937:Diagnosis, Differential; D004171:Diploidy; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000235:genetics; D010920:Placenta / Q000473:pathology; D011123:Polyploidy; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000235:genetics
D004273:DNA, Neoplasm