Plasma levels of retinol, ascorbic acid and alpha-tocopherol in sickle cell anaemia.
The plasma concentrations of the antioxidant vitamins A (retinol), C (ascorbic acid) and E (alpha-tocopherol) were determined in sickle cell anaemia (SCA). It was found that the concentrations of ascorbic acid and alpha-tocopherol were significantly depressed while that of retinol was only slightly reduced. The depletion in the levels of these antioxidant vitamins may account for some of the observed manifestations of SCA such as increased susceptibility to infection and haemolysis.
Essien
E U
EU
Department of Biochemistry, College of Medical Sciences, University of Calabar, Nigeria.
D000328:Adult; D000755:Anemia, Sickle Cell / Q000097:blood* / Q000150:complications; D001205:Ascorbic Acid / Q000097:blood*; D016022:Case-Control Studies; D006801:Humans; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
D014801:Vitamin A; D014810:Vitamin E; D001205:Ascorbic Acid