The effect of intradermal corticosteroids on skin flap edema.
OBJECTIVE
To validate a model for skin flap edema in the piglet and determine whether intraoperative and postoperative intradermal corticosteroids reduce the edema created.


METHODS
Prospective, randomized, matched-control animal model.


METHODS
Animal laboratory.


METHODS
Twenty-five weight-matched purebred Yorkshire piglets.


METHODS
Intraoperative and postoperative injections of intradermal triamcinolone.


METHODS
Flap edema.


RESULTS
A reproducible skin flap edema model was validated in the piglet. Intraoperative intradermal corticosteroids decreased flap edema but postoperative corticosteroids did not.


CONCLUSIONS
Clinical improvement in skin flap and supratip fullness may result from mechanisms other than edema.
Funcik
T
T
Department of Otolaryngology and Communicative Sciences, Medical University of South Carolina, Charleston, USA.
Hochman
M
M
D000818:Animals; D004195:Disease Models, Animal; D004487:Edema / Q000188:drug therapy*; D007271:Injections, Intradermal; D007432:Intraoperative Period; D011182:Postoperative Care; D011446:Prospective Studies; D011897:Random Allocation; D013524:Surgical Flaps; D013552:Swine; D014221:Triamcinolone / Q000008:administration & dosage*
D014221:Triamcinolone