title: [Status of the antioxidant enzyme system in benign symmetrical lipomatosis and changes in it from the use of antioxidant therapy].
abstract: Activity of the antioxidation enzymatic system, involving evaluation of glutathione-reductase, -peroxidase and -S-transferase as well as glucose-6-phosphate dehydrogenase activities, was studied in blood plasma, leukocytes, lymphocytes and erythrocytes of patients with benign symmetric lipomatosis. Elevation in the rate of lipid peroxidation induced the antioxidation enzymatic system and caused a imbalance of its individual units. Intensive antioxidation therapy using "Aevit" allowed correction of the imbalance observed in the enzymatic activity.
authors.forename: L A
authors.initials: LA
authors.lastname: Gavriliuk
authors.forename: A P
authors.initials: AP
authors.lastname: Chebanu
authors.forename: V M
authors.initials: VM
authors.lastname: Topalo
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use; D004338:Drug Combinations; D005954:Glucosephosphate Dehydrogenase / Q000097:blood; D005979:Glutathione Peroxidase / Q000097:blood; D005980:Glutathione Reductase / Q000097:blood; D005982:Glutathione Transferase / Q000097:blood; D006801:Humans; D008068:Lipomatosis / Q000201:enzymology*; D014801:Vitamin A / Q000627:therapeutic use*; D014810:Vitamin E / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D004338:Drug Combinations; D014801:Vitamin A; D014810:Vitamin E; C048974:vitamin A, vitamin E drug combination; D005954:Glucosephosphate Dehydrogenase; D005979:Glutathione Peroxidase; D005980:Glutathione Reductase; D005982:Glutathione Transferase
vernacular_title: Sostoianie antiokislitel'noĭ fermentnoĭ sistemy pri dobrokachestvennom simmetrichnom lipomatoze i ee izmeneniia pod vliianiem antioksidantnoĭ terapii.