[Total thyroidectomy in a young girl presenting C cell hyperplasia at the time of a family screening for medullary carcinoma of the thyroid gland].
The authors report on the case of a 5,8 year-old girl whose father died of medullary thyroid carcinoma. When she was 4,5 year-old, her physical examination was normal but plasma calcitonin and katacalcin (PDN-21) levels were abnormally high in response to pentagastrin infusion. Total thyroidectomy was performed and immunohistochemical staining showed confluent C-cell hyperplasia. No recurrence occurred in this patient over four years on follow-up.
Brichard
B
B
Unité d'endocrinologie, Cliniques Universitaires Saint-Luc, Brussels, Belgique.
Henrot
B
B
Maes
M
M
Rahier
J
J
Jonard
C
C
Malvaux
P
P
D018276:Carcinoma, Medullary / Q000175:diagnosis / Q000235:genetics; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006965:Hyperplasia; D013961:Thyroid Gland / Q000473:pathology* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000235:genetics; D013965:Thyroidectomy
Thyroïdectomie totale chez une fillette présentant une hyperplasie des cellules C dans le cadre d'un dépistage familial de carcinome médullaire de la thyroïde.