title: Calcium and phosphate solubility curves for parenteral nutrient solutions containing aminoplasmal-paed, Aminovenos-N-pad or Moripron-F.
abstract: We investigated the calcium and phosphate compatibility in three amino acid products: Aminoplasmal-paed, Aminovenos-N-pad, Moripron-F. The final TPN sample solution contained 10 per cent dextrose, 1-3 per cent amino acids, 4 mmol/L magnesium sulphate and various combinations of calcium gluconate and dipotassium phosphate. Precipitates and crystallization were inspected visually and microscopically after 24 hrs standing at room temperature. Calcium-phosphate solubility curve were drawn. Among the three amino acid products, Moripron-F gave the highest buffer capacity. These curves are extremely helpful to predict the compatibility of a calcium-phosphate dose in the TPN solution using these three amino acid products.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Thailand.
authors.forename: L
authors.initials: L
authors.lastname: Mo-Suwan
authors.forename: B
authors.initials: B
authors.lastname: Apiromrak
authors.forename: A
authors.initials: A
authors.lastname: Puetpaiboon
mesh_terms: D002118:Calcium / Q000737:chemistry*; D002648:Child; D005217:Fat Emulsions, Intravenous / Q000737:chemistry*; D006801:Humans; D010289:Parenteral Nutrition, Total; D010710:Phosphates / Q000737:chemistry*; D012995:Solubility; D012996:Solutions
chemical_list: D005217:Fat Emulsions, Intravenous; D010710:Phosphates; D012996:Solutions; D002118:Calcium