Evaluation of CMV-vue antigenemia assay for rapid detection of cytomegalovirus in mixed-leukocyte blood fractions.
The CMV-vue antigenemia assay was evaluated by using mixed-leukocyte (ML) blood fractions. Of 234 ML fractions studied, 32 (14%), 23 (10%), and 20 (8.5%) were positive in the CMV-vue assay and conventional and shell vial cultures, respectively. The CMV-vue assay was more sensitive than shell vial cultures for rapid detection of cytomegalovirus. ML fractions are appropriate specimens for the cytomegalovirus antigenemia assay.
Erice
A
A
Department of Laboratory Medicine, University of Minnesota Medical School, Minneapolis 55455, USA.
Holm
M A
MA
Sanjuan
M V
MV
Dunn
D L
DL
Gill
P C
PC
Balfour
H H
HH
D000956:Antigens, Viral / Q000097:blood*; D003587:Cytomegalovirus / Q000276:immunology* / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000821:virology; D005069:Evaluation Studies as Topic; D006801:Humans; D007962:Leukocytes / Q000821:virology; D012680:Sensitivity and Specificity; D014766:Viremia / Q000175:diagnosis* / Q000821:virology; D014773:Virology / Q000379:methods* / Q000706:statistics & numerical data
D000956:Antigens, Viral