title: Childhood acquired epidermolysis bullosa.
abstract: We present the ninth case of epidermolysis bullosa acquisita (EBA) reported in children. As in most of the other childhood cases, the 7-year-old boy described herein had an acute, widespread, inflammatory vesiculobullous eruption with oral involvement. Indirect immunofluorescence on salt-split skin as well as Western immunoblot confirmed the diagnosis of EBA. The patient responded to combined prednisone and dapsone, and was maintained with dapsone alone.
authors.affiliation: Department of Dermatology, Hôpital Pasteur, Nice, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Lacour
authors.forename: P
authors.initials: P
authors.lastname: Bernard
authors.forename: G
authors.initials: G
authors.lastname: Rostain
authors.forename: E
authors.initials: E
authors.lastname: Baechler-Sadoul
authors.forename: A
authors.initials: A
authors.lastname: Pisani
authors.forename: J P
authors.initials: JP
authors.lastname: Ortonne
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000974:Antibodies, Antinuclear; D000962:Antimalarials / Q000627:therapeutic use; D015153:Blotting, Western; D002648:Child; D002675:Child, Preschool; D003622:Dapsone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D016107:Epidermolysis Bullosa Acquisita / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000302:isolation & purification; D007075:Immunoglobulin M / Q000302:isolation & purification; D007223:Infant; D008297:Male; D012867:Skin / Q000737:chemistry
chemical_list: D000305:Adrenal Cortex Hormones; D000974:Antibodies, Antinuclear; D000962:Antimalarials; D007070:Immunoglobulin A; D007075:Immunoglobulin M; D003622:Dapsone