title: The role of mast cells and diet in the onset and maintenance of multiple sclerosis: a hypothesis.
abstract: Mast cells may invade the brain as a consequence of a childhood infection or predisposition, and it is proposed that multiple sclerosis arises due to the effect of various mediators (histamine and protease) released from the perivascular mast cells after stimulation by some diet factor.
authors.affiliation: Institute of Anatomy and Cell Biology, Bergen, Norway.
authors.forename: P G
authors.initials: PG
authors.lastname: Krüger
authors.forename: H I
authors.initials: HI
authors.lastname: Nyland
mesh_terms: D000818:Animals; D002980:Climate; D004032:Diet; D010450:Endopeptidases / Q000378:metabolism; D006632:Histamine / Q000378:metabolism; D006801:Humans; D008407:Mast Cells / Q000502:physiology*; D009103:Multiple Sclerosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D010684:Philosophy; D012307:Risk Factors
chemical_list: D006632:Histamine; D010450:Endopeptidases