Chemical regulation of pulmonary airway tone.
Over the past three years, substantial progress has been made in dissecting out the role of each of these individual effector systems, namely, the leukotrienes, neuropeptides, and nitrogen oxides. The next major challenge is to understand how they function in an integrated fashion.
Drazen
J M
JM
Pulmonary and Critical Care Division, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Gaston
B
B
Shore
S A
SA
D000403:Airway Resistance / Q000502:physiology*; D001249:Asthma / Q000503:physiopathology; D001980:Bronchi / Q000502:physiology; D016084:Bronchoconstriction; D006801:Humans; D015289:Leukotrienes / Q000502:physiology*; D008168:Lung / Q000502:physiology; D008297:Male; D008407:Mast Cells / Q000378:metabolism; D009130:Muscle, Smooth / Q000502:physiology; D009479:Neuropeptides / Q000502:physiology*; D009589:Nitrogen Oxides / Q000378:metabolism*; D012143:Respiratory Physiological Phenomena
D015289:Leukotrienes; D009479:Neuropeptides; D009589:Nitrogen Oxides