title: Total antioxidant activity of low density lipoproteins and the relationship with alpha-tocopherol status.
abstract: A rapid method is described for measuring the antioxidant activity of low density lipoproteins. Studies were undertaken on individuals attending a hyperlipidaemia clinic, an unsupplemented group and a group after supplementation with 300 mg dl-alpha-tocopherol acetate for nine weeks. The results show a positive correlation between the antioxidant activity and alpha-tocopherol content of LDL in the supplemented group.
authors.affiliation: Free Radical Research Group, UMDS-Guy's Hospital, London, UK.
authors.forename: N J
authors.initials: NJ
authors.lastname: Miller
authors.forename: G
authors.initials: G
authors.lastname: Paganga
authors.forename: S
authors.initials: S
authors.lastname: Wiseman
authors.forename: W
authors.initials: W
authors.lastname: Van Nielen
authors.forename: L
authors.initials: L
authors.lastname: Tijburg
authors.forename: P
authors.initials: P
authors.lastname: Chowienczyk
authors.forename: C A
authors.initials: CA
authors.lastname: Rice-Evans
mesh_terms: D000975:Antioxidants; D002784:Cholesterol / Q000097:blood; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood*; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000097:blood / Q000494:pharmacology; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
chemical_list: D000975:Antioxidants; D008077:Lipoproteins, LDL; D014810:Vitamin E; D002784:Cholesterol; D024502:alpha-Tocopherol; D024505:Tocopherols