Hereditary gingival fibromatosis. Report of an extensive four-generation pedigree.
A Brazilian family with hereditary gingival fibromatosis is described with multiple affected subjects in four generations. A total of 50 (48%), of 105 at-risk offspring in a family of 132 members were affected, consistent with an autosomal dominant mode of inheritance. This family appears to represent the largest pedigree with this condition reported in the literature.
Bozzo
L
L
Department of Oral Pathology, Faculty of Odontology at Piracicaba, University of Campinas, Piracicaba, Brazil.
de Almedia
O P
OP
Scully
C
C
Aldred
M J
MJ
D000328:Adult; D000368:Aged; D001938:Brazil; D002648:Child; D005260:Female; D005351:Fibromatosis, Gingival / Q000235:genetics*; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree