title: DNA topoisomerases.
abstract: In the past year, the atomic structures of three fragments of type I DNA topoisomerases were elucidated. Together with the atomic structure of a fragment of bacterial gyrase, this wealth of structural information is helping to further our understanding of the mechanism of action of topoisomerases.
authors.affiliation: Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, IL 60208-3500, USA.
authors.forename: A
authors.initials: A
authors.lastname: Sharma
authors.forename: A
authors.initials: A
authors.lastname: Mondragón
mesh_terms: D000818:Animals; D004264:DNA Topoisomerases, Type I / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D007527:Isoenzymes / Q000737:chemistry / Q000378:metabolism; D011487:Protein Conformation
chemical_list: D007527:Isoenzymes; D004264:DNA Topoisomerases, Type I