title: Acute lymphoblastic transformation of essential thrombocythaemia.
abstract: Essential thrombocythaemia is a myeloproliferative disorder which may transform to acute myeloid leukaemia, especially following therapy with alkylating agents or radioactive phosphorus. We describe the rare occurrence of acute lymphoblastic leukaemia transformation in a patient with known essential thrombocythaemia.
authors.affiliation: Haematology Department, Leicester Royal Infirmary.
authors.forename: P T
authors.initials: PT
authors.lastname: Murphy
authors.forename: M
authors.initials: M
authors.lastname: Sivakumaran
authors.forename: F
authors.initials: F
authors.lastname: van Rhee
authors.forename: A E
authors.initials: AE
authors.lastname: Watmore
authors.forename: V E
authors.initials: VE
authors.lastname: Mitchell
mesh_terms: D006801:Humans; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000209:etiology*; D013920:Thrombocythemia, Essential / Q000150:complications*