Determination and confirmation of methyl p-hydroxybenzoate in royal jelly and other foods produced by the honey bee.
Methyl p-hydroxybenzoate (methyl paraben) in foods produced by the Honey Bee was determined by HPLC and confirmed by GC-MS. The compound was detected at a mean concentration of 22.3 +/- 6.8 mg/kg (between 14.2 and 31.9 mg/kg) in commercial royal jelly, but was not detected in honey, propolis or pollen lumps at the detection limit of 1 mg/kg. Fresh royal jelly collected from apiaries contained methyl p-hydroxybenzoate at a concentration of 20.3 +/- 4.7 mg/kg (between 12.5 and 31.7 mg/kg). These results indicate that the methyl p-hydroxybenzoate in royal jelly is not added but is a natural component.
Ishiwata
H
H
National Institute of Health Sciences, Tokyo, Japan.
Takeda
Y
Y
Yamada
T
T
Watanabe
Y
Y
Hosagai
T
T
Ito
S
S
Sakurai
H
H
Aoki
G
G
Ushiama
N
N
D000818:Animals; D001516:Bees / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D008401:Gas Chromatography-Mass Spectrometry; D006722:Honey / Q000032:analysis*; D010226:Parabens / Q000032:analysis*
D010226:Parabens; C015358:methylparaben