title: The effect of irrigation with chlorhexidine or saline on plaque vitality.
abstract: 24 adult patients suffering from Adult periodontitis were assigned to 4 groups: the 1st rinsed for 1 min with 0.2% chlorhexidine gluconate (CHX); the 2nd group were irrigated for 15 s with 0.2% CHX in a pulsed oral irrigator; the 3rd group rinsed for 1 min with saline and the 4th group were irrigated for 15 s with saline. Plaque vitality was measured after the 4 experimental procedures, using the method described by Netuschil et al. and scored using the method described by Rundegren et al. The results showed that a single rinse or irrigation with 0.2% CHX solution decreased the % of viable micro-organisms, but the vitality of the bacteria remained unchanged in saline groups. Statistical analysis indicated that irrigation with CHX was more effective at reducing plaque vitality than rinsing with CHX.
authors.affiliation: Department of Restorative Dentistry, School of Clinical Dentistry, University of Sheffield, UK.
authors.forename: T F
authors.initials: TF
authors.lastname: Walsh
authors.forename: E
authors.initials: E
authors.lastname: Unsal
authors.forename: L G
authors.initials: LG
authors.lastname: Davis
authors.forename: O
authors.initials: O
authors.lastname: Yilmaz
mesh_terms: D000328:Adult; D001419:Bacteria / Q000187:drug effects*; D018407:Bacterial Physiological Phenomena; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000382:microbiology*; D004996:Ethidium; D005260:Female; D005452:Fluoresceins; D006801:Humans; D008297:Male; D008856:Microscopy, Fluorescence; D008875:Middle Aged; D009067:Mouthwashes; D010518:Periodontitis / Q000188:drug therapy / Q000382:microbiology; D012965:Sodium Chloride; D007507:Therapeutic Irrigation
chemical_list: D005452:Fluoresceins; D009067:Mouthwashes; D012965:Sodium Chloride; D004996:Ethidium; C010882:chlorhexidine gluconate; D002710:Chlorhexidine; C018506:diacetylfluorescein