Visual processing, lateralization and syndromes of schizotypy.
There is an association between positive features of schizotypy and dyslexia, largely involving distortions of visual and auditory perception and associated cognitive anomalies. In dyslexia, there is strong evidence for a disorder of subcortical magnocellular pathways, which may underlie these perceptual aberrations. Here we investigated visual processing in relation to three syndromes of schizotypy-Active, Withdrawn and Unreality-in normal adults, using a "dot localization" test of visual direction sense on which dyslexics perform poorly, and which should be sensitive to magnocellular dysfunction. Results showed that increased error scores were associated with both the positive syndromes, Active and Unreality, which in this study were highly correlated. There were also interactions between each syndrome and the direction of errors, such that high scorers on the Unreality and Active syndromes made more errors on leftward trials, while high Withdrawn subjects made fewer left and more right errors. Mixed handers also showed poorer performance than consistent handers. The evidence of poor visual direction sense in relation to positive syndromes of schizotypy and mixed handedness is consistent with the previous results for dyslexics, who also show these features. The opposite lateralization of errors in the positive v negative syndromes of schizotypy is in keeping with the model of hemisphere imbalance and patterns of cognitive asymmetry which distinguish Active from Withdrawn syndromes. These results are considered in relation to the proposal that a disorder of magnocellular function may underlie the perceptual distortions which are common to dyslexia and positive syndromes of schizotypy.
Richardson
A J
AJ
Department of Psychiatry, Charing Cross and Westminister Medical School, London, UK.
Gruzelier
J
J
D000293:Adolescent; D000328:Adult; D004410:Dyslexia / Q000523:psychology; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D010556:Personality Tests; D012569:Schizotypal Personality Disorder / Q000503:physiopathology* / Q000523:psychology*; D013028:Space Perception / Q000502:physiology; D013647:Task Performance and Analysis; D014796:Visual Perception / Q000502:physiology*