Catheter-related infections by Hansenula anomala in children.
During August and September, 1992, we experienced 4 cases of Hansenula anomala (H. anomala, synonym Pichia anomala) fungemia in immunocompromised patients. Two patients had been suffering from a malignant disease, 3 of them had received broad-spectrum antibiotics and a central venous catheter (CVC) had been inserted in all of them. H. anomala was isolated as the sole pathogen from all 4 patients. Three of them responded favorably to fluconazole after withdrawal of the catheter, but one failed. H. anomala should be considered as a possible cause of catheter-related infections.
Yamada
S
S
Department of Pediatrics, Kurume University School of Medicine, Japan.
Maruoka
T
T
Nagai
K
K
Tsumura
N
N
Yamada
T
T
Sakata
Y
Y
Tominaga
K
K
Motohiro
T
T
Kato
H
H
Makimura
K
K
D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D016469:Fungemia / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010843:Pichia / Q000187:drug effects / Q000302:isolation & purification
D015725:Fluconazole