Genetic and physical mapping of five novel microsatellite markers on human Xp21.1-p11.22.
Five polymorphic CA-dinucleotide repeats, identified in cosmids from the short arm of the human X chromosome, have been characterized and localized to Xp21.1 (DXS572), Xp11.4 (DXS556, DXS574), and Xp11.22-p11.23 (DXS722, DXS573). Genetic mapping with respect to five reference markers that include the gene for CGD (CYBB in Xp21.1), complemented by physical mapping information, has indicated the order tel-DXS572-CYBB-DXS1110-DXS556-DXS574-D XS7-DXS426-DXS722-DXS573-DXS255-cen.
Thiselton
D L
DL
Department of Molecular Genetics, Institute of Ophthalmology, London, United Kingdom.
Lindsay
S
S
Kamakari
S
S
Hardcastle
A J
AJ
Roustan
P
P
Bhattacharya
S S
SS
D000818:Animals; D001483:Base Sequence; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D017931:DNA Primers; D004276:DNA, Satellite / Q000235:genetics*; D006580:Genetic Carrier Screening; D005819:Genetic Markers; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D008540:Meiosis; D051379:Mice; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D014960:X Chromosome
D017931:DNA Primers; D004276:DNA, Satellite; D005819:Genetic Markers