Anti-neutrophil cytoplasmic antibody associated glomerulonephritis in a patient with Down's syndrome.
A 9-year-old boy with Down's syndrome developed a glomerulonephritis associated with crescents and anti-neutrophil cytoplasmic antibodies (ANCA). The patient also had type 1 diabetes mellitus, chronic lymphocytic thyroiditis, and bronchial asthma. Prednisone therapy resulted in an improvement in renal function and a reduction in ANCA titers.
Robson
W L
WL
Division of Pediatric Nephrology, Children's Hospital, Greenville Hospital System, South Carolina 29605-4253, USA.
Leung
A K
AK
Woodman
R C
RC
Trevenen
C L
CL
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood*; D002648:Child; D004314:Down Syndrome / Q000097:blood / Q000150:complications*; D005921:Glomerulonephritis / Q000097:blood / Q000150:complications*; D006801:Humans; D008297:Male
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D015415:Biomarkers