title: KR-25003, a potent analgesic capsaicinoid.
abstract: The crystal structure of N-[3-(3,4-dimethylphenyl)propyl] (4-hydroxy-3-methoxyphenyl)acetamide, C20H25NO3, was determined to a final R value of 0.047. The vanilloid, amide and dimethylphenyl groups of the compound are nearly perpendicular with respect to one another. The overall conformation in the crystalline state is somewhat different from that of other capsaicinoids. The molecules are stabilized by intermolecular hydrogen bonds.
authors.affiliation: Korea Research Institute of Chemical Technology, Taejon.
authors.forename: N S
authors.initials: NS
authors.lastname: Park
authors.forename: I Y
authors.initials: IY
authors.lastname: Park
authors.forename: J C
authors.initials: JC
authors.lastname: Lee
authors.forename: Y B
authors.initials: YB
authors.lastname: Kim
mesh_terms: D000700:Analgesics / Q000737:chemistry*; D002211:Capsaicin / Q000031:analogs & derivatives* / Q000737:chemistry; D003460:Crystallization; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008968:Molecular Conformation; D015394:Molecular Structure
chemical_list: D000700:Analgesics; C094051:KR 25003; D002211:Capsaicin