Antivenom activity of opossum (Didelphis marsupialis) serum fraction.
We have found an opossum serum fraction of approximately 97,000 mol. wt to be highly proficient in inactivating the haemorrhagic and proteolytic fractions of Bothrops lanceolatus venom. This antivenom substance, isolated from opossum serum or a synthetic peptide based on the aforementioned protein, would probably be useful in the medical management of Bothrops accidents.
Rodriguez-Acosta
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A
Univerisdad Central de Venezuela, Instituto de Medicina Tropical, Caracas, Venezuela.
Aguilar
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I
Giron
M E
ME
D000818:Animals; D000997:Antivenins / Q000494:pharmacology*; D017837:Bothrops; D003435:Crotalid Venoms / Q000037:antagonists & inhibitors*; D006801:Humans; D008970:Molecular Weight; D009893:Opossums / Q000097:blood*
D000997:Antivenins; D003435:Crotalid Venoms