title: [Use of GDC coils in treatment of inoperable aneurysms: report of initial experiences].
abstract: The authors report on the endovascular occlusion of intracranial aneurysms with GDC coils in 8 patients. In 2 cases, the diagnosis was made because of subarachnoidal hemorrhage. Three patients complained about headache, and one patient had an oculomotor palsy. The findings were incidental in 2 cases. Angiography demonstrated an aneurysm of the internal carotid artery in 4 of the 6 females and in the 2 males (mean age 50 years) and a basilar artery aneurysm in 4 cases. The indication for endovascular treatment was established after carefully weighing the risks against those of a neurosurgical intervention. It was possible to occlude completely the aneurysm by induced electrothrombosis and to preserve the patency of the main vessel in all cases. One female (case 6) developed a hemiparesis due to embolism of a medial branch six hours after treatment. This receded completely after thrombolysis with urokinase. A second patient showed further growth of the internal carotid aneurysm on the control angiogram obtained after six months. Our initial results are encouraging. With increasing experience, endovascular treatment is expected to become the method of choice for the treatment of most inoperable cerebral aneurysms.
authors.affiliation: Neurochirurgische Klinik, Universitätsklinikum Steglitz.
authors.forename: H J
authors.initials: HJ
authors.lastname: Meisel
authors.forename: G
authors.initials: G
authors.lastname: Rodesch
authors.forename: H
authors.initials: H
authors.lastname: Alvarez
authors.forename: P
authors.initials: P
authors.lastname: Lasjaunias
authors.forename: M
authors.initials: M
authors.lastname: Brock
mesh_terms: D000328:Adult; D000368:Aged; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000628:therapy; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D002542:Intracranial Embolism and Thrombosis / Q000000981:diagnostic imaging / Q000628:therapy; D008297:Male; D008875:Middle Aged; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000628:therapy; D015912:Thrombolytic Therapy; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging / Q000628:therapy
chemical_list: D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Der Einsatz von GDC coils zur Behandlung inoperabler Aneurysmen: Erster Erfahrungsbericht.