title: Efficacy of Cymelarsan in the treatment of natural chronic Trypanosoma evansi infection in camels in the Sudan.
abstract: The efficacy of Cymelarsan, administered by intramuscular (i/m) injection in the treatment of chronic cases of camel trypanosomosis due to Trypanosoma evansi, was tested under controlled laboratory conditions. It was confirmed that Cymelarsan is a safe drug for use in dromedary camels when administered i/m at dose rates of 0.25 or 0.50 mg/kg body weight. During the 90 days post-treatment no relapses occurred at either dose rate. Hence, the drug was found to be fully effective against the chronic form of the natural disease. A dose of 0.25 mg/kg body weight of Cymelarsan given i/m is recommended.
authors.affiliation: Tsetse and Trypanosomiasis Control Department, Central Veterinary Research Administration, Khartoum, Soudan.
authors.forename: M M
authors.initials: MM
authors.lastname: Musa
authors.forename: A M
authors.initials: AM
authors.lastname: Abdoon
authors.forename: B T
authors.initials: BT
authors.lastname: Nasir
authors.forename: Y I
authors.initials: YI
authors.lastname: Salim
authors.forename: A Y
authors.initials: AY
authors.lastname: Abdel-Rahman
authors.forename: A M
authors.initials: AM
authors.lastname: Shommein
mesh_terms: D000818:Animals; D001152:Arsenicals / Q000627:therapeutic use*; D002162:Camelus / Q000469:parasitology*; D013397:Sudan; D014344:Trypanocidal Agents / Q000627:therapeutic use*; D014353:Trypanosomiasis, African / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D001152:Arsenicals; D014344:Trypanocidal Agents; C062789:melaminylthioarsenate