title: [Exudative pericarditis with pleural plaques caused by exposure to asbestos, resolved with steroidal treatment].
abstract: We report a case of a 73-year old railwayman with an asymptomatic large pericardial effusion diagnosed by a routine echocardiogram. By clinical and laboratory tests we excluded an immune, infectious, tuberculous and neoplastic origin of the pericardial effusion. A computed tomography scan of the thorax showed left pleural plaques. Pleural and pericardial biopsies showed fibrohyaline plaques and diffuse aspecific, chronic inflammation consistent with asbestos exposure. By using steroid treatment there was no further evidence of pericardial inflammation or pericardial effusion at 8 month follow-up. Steroid drugs are therefore suggested as a first choice treatment in patients with pleuropericardial effusion as well as chronic asbestos exposure.
authors.affiliation: Istituto di Patologia Speciale Medica, Università degli Studi di Bologna.
authors.forename: E
authors.initials: E
authors.lastname: Cordioli
authors.forename: C
authors.initials: C
authors.lastname: Tondini
authors.forename: C
authors.initials: C
authors.lastname: Pizzi
authors.forename: R
authors.initials: R
authors.lastname: Bugiardini
mesh_terms: D000368:Aged; D001194:Asbestos / Q000009:adverse effects*; D001195:Asbestosis / Q000150:complications*; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D010490:Pericardial Effusion / Q000188:drug therapy* / Q000209:etiology*; D010493:Pericarditis / Q000188:drug therapy* / Q000209:etiology*
chemical_list: D001194:Asbestos; D008775:Methylprednisolone
vernacular_title: Pericardite essudativa associata a placche pleuriche da esposizione all'asbesto, risolta da trattamento steroideo.