title: Gestational trophoblastic tumors of the uterus: MR imaging--pathologic correlation.
abstract: The purpose of this study is to evaluate the MR findings of gestational trophoblastic tumors (GTTs). Ten patients who confirmed the diagnosis (4 choriocarcinomas and 6 invasive moles) constituted the basis of our study. The MR findings from these patients were prospectively correlated with the histopathology of resected tumor specimens. MR findings of 4 patients with choriocarcinomas were well-defined, hemorrhagic masses with central necrosis. In contrast, 6 patients with invasive moles showed ill-defined, permeative masses with densely enhanced solid components and tiny cystic lesions. The trophoblastic proliferation, coagulation necrosis, and molar villi had varying signal intensities on T1- and T2-weighted images. Our results suggest that MR imaging is a promising tool for noninvasive morphologic analysis of GTTs.
authors.affiliation: Department of Radiology, Catholic University Medical College, Seoul, Korea.
authors.forename: H K
authors.initials: HK
authors.lastname: Ha
authors.forename: J K
authors.initials: JK
authors.lastname: Jung
authors.forename: M K
authors.initials: MK
authors.lastname: Jee
authors.forename: H H
authors.initials: HH
authors.lastname: Kim
authors.forename: J M
authors.initials: JM
authors.lastname: Lee
authors.forename: S E
authors.initials: SE
authors.lastname: Nam-Koong
authors.forename: S J
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D000328:Adult; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011247:Pregnancy; D011446:Prospective Studies; D014328:Trophoblastic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery