title: The prognostic value of the EEG in asphyxiated newborns.
abstract: Peripartal asphyxia is still one of the most important factors of neonatal morbidity and mortality and accounts for the majority of non-progressive neurological deficits seen in children. A set of evaluations that may consistently predict outcome in this patient population would be valuable. The purpose of the present retrospective study was to investigate the prognostic value of the early neonatal EEG and Sarnat scoring obtained in 23 asphyxiated term newborns. All infants met strict entrance criteria, regarding asphyxia, and received standard treatment. The relationship between the Sarnat scoring, the early EEG findings, and the clinical follow up examination (at 1,5-7 years) were studied using the Pearson Correlation test and multiple regression. Our study clearly demonstrates a strong correlation between the early neonatal EEG and outcome, even regarding the prediction of minor sequelae (r = 0.79, p < 0.0001). The early neonatal EEG is more accurate in predicting the ultimate clinical outcome than the Sarnat scoring.
authors.affiliation: Department of Clinical Neurophysiology, Academic Hospital Nijmegen, The Netherlands.
authors.forename: H B
authors.initials: HB
authors.lastname: van Lieshout
authors.forename: J W
authors.initials: JW
authors.lastname: Jacobs
authors.forename: J J
authors.initials: JJ
authors.lastname: Rotteveel
authors.forename: W
authors.initials: W
authors.lastname: Geven
authors.forename: M
authors.initials: M
authors.lastname: v't Hof
mesh_terms: D001238:Asphyxia Neonatorum / Q000175:diagnosis*; D001921:Brain / Q000503:physiopathology; D003700:Delta Rhythm; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index