Hemodynamic study of different angled end-to-side anastomoses.
This study assessed the postoperative microvascular hemodynamics in end-to-side arterial anastomoses of varied angles in order to determine whether the angle of the anastomosis affects arterial flow. Thirty male rats were divided into three groups of ten. Carotid to carotid end-to-side anastomoses were performed with anastomotic angles of 45, 90, and 135 degrees. Postoperative flow was assessed using high frequency pulsed Doppler ultrasound (HFPDU) at 30 and 120 min postoperatively. Measurements at 30 min demonstrated significant differences in flow, with the 45 degrees grafted vessels utilizing 56.5% of total carotid flow, and the 90 degrees and 135 degrees anastomoses appropriating 46.5% and 43.2% of flow, respectively (comparing 45 degrees to both 90 degrees, P < 0.05, and 135 degrees, P < 0.002). The change from baseline in 45 degrees and 90 degrees groups dissipated over a 2 hr postoperative period, but flow in the grafted vessels in the 135 degrees group continued well below 50% at 39.9% (comparing to both 45 degrees and 90 degrees, P < 0.001), thereby displaying a significant difference in the postoperative arterial flow of varied angled microanastomoses.
Zhang
L
L
Institute of Reconstructive Plastic Surgery, New York University Medical Center, NY 10016, USA.
Moskovitz
M
M
Piscatelli
S
S
Longaker
M T
MT
Siebert
J W
JW
D000714:Anastomosis, Surgical / Q000379:methods*; D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000502:physiology* / Q000601:surgery*; D017536:Carotid Artery, Common / Q000601:surgery; D006439:Hemodynamics; D018056:Hemorheology; D008297:Male; D008833:Microcirculation; D008866:Microsurgery / Q000379:methods*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012039:Regional Blood Flow / Q000502:physiology; D013536:Suture Techniques; D013997:Time Factors; D018617:Ultrasonography, Doppler, Pulsed