[The effect of antidepressants on the indices of the cardiointervalogram in intact rats and during the deprivation of paradoxical sleep].
The acute and chronic administration of antidepressants (amitriptyline, imipramine, befol) to rats led to the sympathetic influences of a cardiointervalogram as reduced cardiointervals and its increased amplitude and tension index. Imipramine was found to be effective in eliminating disadaptational abnormalities in cardiac performance, which promoted REM-sleep deprivation.
Arushenian
A E
AE
Semenova
F O
FO
Fedulova
I V
IV
D000222:Adaptation, Physiological / Q000187:drug effects; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D012892:Sleep Deprivation / Q000502:physiology*; D012895:Sleep, REM / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors
D000928:Antidepressive Agents
Vliianie antidepressantov na pokazateli kardiointervalogrammy u intaktnykh krys i pri lishenii paradoksal'nogo sna.