title: Endometrial squamous cell carcinoma following whole pelvic radiation therapy: response to carboplatin.
abstract: A case of Stage IV endometrial squamous cell carcinoma occurring 8 years after a low anterior resection and whole pelvic radiation therapy for a Dukes D colon carcinoma is presented. Koilocytosis was present in the tumor. There was no evidence of human papillomavirus antigen or DNA in the tumor. The patient was treated with surgery followed by six cycles of carboplatin chemotherapy. At the completion of chemotherapy there was no clinical or radiological evidence of disease. The tumor recurred 9 months postchemotherapy and the patient died of disease 17 months postdiagnosis.
authors.affiliation: Department of Obstetrics and Gynecology, Pennsylvania State University Hospital, Hershey 17033, USA.
authors.forename: J I
authors.initials: JI
authors.lastname: Sorosky
authors.forename: P F
authors.initials: PF
authors.lastname: Kaminski
authors.forename: J
authors.initials: J
authors.lastname: Kreider
authors.forename: E S
authors.initials: ES
authors.lastname: Podczaski
authors.forename: G J
authors.initials: GJ
authors.lastname: Olt
authors.forename: R
authors.initials: R
authors.lastname: Zaino
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy / Q000601:surgery; D000368:Aged; D016190:Carboplatin / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D003110:Colonic Neoplasms / Q000532:radiotherapy / Q000601:surgery; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000235:genetics* / Q000382:microbiology; D027383:Papillomaviridae; D011878:Radiotherapy / Q000009:adverse effects
chemical_list: D016190:Carboplatin