[The epithelium-dependent mechanism of the bronchodilating action of adrenaline].
The involvement of the epithelium in the adrenergic reactions of airways smooth muscles was studied. The epithelium-dependent pathway of the bronchodilating action of catecholamines, which played a minor role was found to become decisive in some cases. In that case the epithelial inflammatory lesion could be a cause of reducing the response of the bronchi to catecholamines.
Kapilevich
L V
LV
Baskakov
M B
MB
Kuskov
M V
MV
Petrov
E Iu
EIu
Kovalev
I V
IV
Medvedev
M A
MA
D000818:Animals; D001980:Bronchi / Q000187:drug effects* / Q000502:physiology; D001993:Bronchodilator Agents / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000494:pharmacology*; D004848:Epithelium / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D011817:Rabbits; D051381:Rats; D014132:Trachea / Q000187:drug effects / Q000502:physiology
D001993:Bronchodilator Agents; D004837:Epinephrine
Epiteliĭzavisimyĭ mekhanizm bronkhorasshiriaiushchego deĭstviia adrenalina.