[Preliminary study on pathophysiology of liver-qi deficiency syndrome].
The authors advocate a program for diagnosing Liver-Qi Deficiency Syndrome (LQDS) based on the TCM theory and clinical practice. Through investigation, LQDS was found to be widely existed as latent period or as external manifestation, which occupied 18.85% in Qi Deficiency Syndrome. The subjects were divided into four groups including normal group, Spleen-Qi Deficiency Syndrome (SQDS) group, LQDS with Liver diseases (LD) and LQDS with non-Liver diseases (NLD) group. In order to explore the essence, the simultaneous determinations were done on lactate dehydrogenase (LDH) and its isoenzyme, dopamine beta-hydroxylase (D beta H), trace element Zn and Cu, and other serological indexes such as GPT, TP, Alb, A/G, etc. The results were, the content of LDH and trace element Zn in both LQDS-NLD and SQDS were significantly lower than that of normal group. D beta H reflecting sympathetic nerve function in LQDS-NLD was significantly higher than that of both normal and SQDS group; comparing LQDS-LD and LQDS-NLD group, the content of GPT, LDH, LDH5 and trace element Cu in former was significantly higher than that of the latter, but the content of TP, Alb, A/G, D beta H and Zn in former was remarkably lower than that of the latter. In order to avoid confusion, in studying this syndrome, one should distinguish LD and NLD.
Chen
J X
JX
Beijing University of TCM.
Yang
W Y
WY
Liang
R
R
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D004299:Dopamine beta-Hydroxylase / Q000097:blood*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008107:Liver Diseases / Q000097:blood / Q000201:enzymology*; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D013158:Splenic Diseases / Q000097:blood / Q000201:enzymology; D016711:Yang Deficiency / Q000097:blood / Q000201:enzymology; D015032:Zinc / Q000097:blood
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D004299:Dopamine beta-Hydroxylase; D000410:Alanine Transaminase; D015032:Zinc