title: The effect of intradermal corticosteroids on skin flap edema.
abstract: OBJECTIVE
  To validate a model for skin flap edema in the piglet and determine whether intraoperative and postoperative intradermal corticosteroids reduce the edema created.
  
  
  METHODS
  Prospective, randomized, matched-control animal model.
  
  
  METHODS
  Animal laboratory.
  
  
  METHODS
  Twenty-five weight-matched purebred Yorkshire piglets.
  
  
  METHODS
  Intraoperative and postoperative injections of intradermal triamcinolone.
  
  
  METHODS
  Flap edema.
  
  
  RESULTS
  A reproducible skin flap edema model was validated in the piglet. Intraoperative intradermal corticosteroids decreased flap edema but postoperative corticosteroids did not.
  
  
  CONCLUSIONS
  Clinical improvement in skin flap and supratip fullness may result from mechanisms other than edema.
authors.affiliation: Department of Otolaryngology and Communicative Sciences, Medical University of South Carolina, Charleston, USA.
authors.forename: T
authors.initials: T
authors.lastname: Funcik
authors.forename: M
authors.initials: M
authors.lastname: Hochman
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004487:Edema / Q000188:drug therapy*; D007271:Injections, Intradermal; D007432:Intraoperative Period; D011182:Postoperative Care; D011446:Prospective Studies; D011897:Random Allocation; D013524:Surgical Flaps; D013552:Swine; D014221:Triamcinolone / Q000008:administration & dosage*
chemical_list: D014221:Triamcinolone