title: Occupational allergic contact dermatitis from ethyl cyanoacrylate.
abstract: Glues based on cyanoacrylates are widely used as contact adhesives for metal, glass, rubber, plastics and textiles, as well for biological materials, including binding tissues and sealing wounds in surgery. In this paper, an apprentice cobbler with an occupational allergic contact dermatitis from an ethyl cyanoacrylate glue, in which the major monomer was shown to be the sensitizer, is reported. Initial patch testing with the cyanoacrylate glue dissolved in acetone with the Finn Chamber (aluminium) technique yielded false-negative reactions. Positive test reactions were obtained with the same preparations using Van der Bend chambers. With petrolatum as vehicle for the glue, there was no difference between Finn Chamber technique and Van der Bend chamber technique. The role of aluminium in the false-negative reactions is discussed.
authors.affiliation: Department of Occupational Dermatology, General Hospital Malmö, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Bruze
authors.forename: B
authors.initials: B
authors.lastname: Björkner
authors.forename: J P
authors.initials: JP
authors.lastname: Lepoittevin
mesh_terms: D000005:Abdomen; D000269:Adhesives / Q000009:adverse effects*; D000328:Adult; D003487:Cyanoacrylates / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology*; D005542:Forearm; D006229:Hand Dermatoses / Q000139:chemically induced; D006801:Humans; D008297:Male; D010328:Patch Tests / Q000379:methods; D012775:Shoes
chemical_list: D000269:Adhesives; D003487:Cyanoacrylates; C029054:ethyl 2-cyanoacrylate