title: Arf proteins: the membrane traffic police?
abstract: Cofactor for cholera toxin; activator of phospholipase D; regulator of coat-protein assembly; inhibitor of membrane traffic; ability to cause expansion of the endoplasmic reticulum and vesiculation of the Golgi; sensitivity to membrane phospholipids--each of these activities has been attributed to Arf proteins. Can a single molecular mechanism link them all?
authors.affiliation: Laboratory of Biological Chemistry, Developmental Therapeutics Program, DCT, NCI, Bethesda, MD 20892, USA.
authors.forename: A L
authors.initials: AL
authors.lastname: Boman
authors.forename: R A
authors.initials: RA
authors.lastname: Kahn
mesh_terms: D020727:ADP-Ribosylation Factors; D000818:Animals; D019204:GTP-Binding Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008563:Membrane Lipids / Q000378:metabolism; D008954:Models, Biological; D008958:Models, Molecular; D010743:Phospholipids / Q000378:metabolism
chemical_list: D008563:Membrane Lipids; D010743:Phospholipids; D019204:GTP-Binding Proteins; D020727:ADP-Ribosylation Factors