title: Levonorgestrel intrauterine device in the treatment of menorrhagia in Chinese women: efficacy versus acceptability.
abstract: Ten Chinese women who had menorrhagia without organic cause and suffered from anaemia were treated with levonorgestrel intrauterine device for a total of 129 woman-months. There was a 54%, 87% and 95% reduction in menstrual blood loss at the first, third and sixth month of treatment when compared with the pretreatment cycle. These percentages of reduction were statistically significant, with p values of 0.004, 0.03 and 0.008, respectively. There was a median increase in menstrual cycle length of 12 days in nine months. Fifteen percent of the menstrual cycles were longer than 60 days. The total bleeding days increased by 4 days at the third menstrual cycles, but reduced to a median of 6 days at 6 months. Seventy-six percent of the menstrual bleeding was in the form of spotting. These Chinese women accepted such menstrual alterations. There was no hormonal side effects. All women preferred the device to hysterectomy. Levonorgestrel intrauterine device appeared to be an effective and acceptable treatment for menorrhagia in perimenopausal Chinese women.
authors.affiliation: Department of Obstetrics and Gynaecology, Queen Mary Hospital, University of Hong Kong.
authors.forename: G W
authors.initials: GW
authors.lastname: Tang
authors.forename: S S
authors.initials: SS
authors.lastname: Lo
mesh_terms: D000328:Adult; D000740:Anemia / Q000209:etiology; D002681:China; D005260:Female; D006801:Humans; D007434:Intrauterine Devices; D016912:Levonorgestrel / Q000008:administration & dosage* / Q000627:therapeutic use; D008595:Menorrhagia / Q000150:complications / Q000188:drug therapy*; D008875:Middle Aged; D013997:Time Factors
chemical_list: D016912:Levonorgestrel