title: Secretory endometrial adenocarcinoma in a patient on tamoxifen for breast cancer: a report of a case.
abstract: Well-differentiated endometrial adenocarcinoma of the secretory type (FIGO Grade 1) with minimal myometrial invasion occurred in a postmenopausal patient on tamoxifen therapy 5 years after mastectomy for breast carcinoma. We believe that this is the first report of secretory carcinoma of the endometrium associated with tamoxifen use. This unusual pattern of low-grade endometrial carcinoma adds to the spectrum of uterine neoplasia associated with tamoxifen therapy.
authors.affiliation: Department of Obstetrics and Gynecology, State University of New York, Health Science Center, Syracuse 13210, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Folk
authors.forename: M T
authors.initials: MT
authors.lastname: Mazur
authors.forename: G L
authors.initials: GL
authors.lastname: Eddy
authors.forename: A G
authors.initials: AG
authors.lastname: Musa
mesh_terms: D000230:Adenocarcinoma / Q000139:chemically induced* / Q000378:metabolism; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy*; D016889:Endometrial Neoplasms / Q000139:chemically induced* / Q000378:metabolism; D005260:Female; D006801:Humans; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D013629:Tamoxifen