[The age-related characteristics of the immune reaction of the mucosa of the gastric antrum in chronic gastritis].
Stomach biopsies from 16 adult patients at the age from 18 to 55 years, 16 adults of 56-68 years and 23 children were studied histologically, immunohistochemically and morphometrically. The frequency of Helicobacter pylori findings was dependent on the age. Local production of IgM and IgG was higher in the adults of young and mature age. Number of IgA producing cells decreased and that of IgG producing cells sharply increased in the aged persons; in this category also was increased the number of intraepithelial lymphocytes and of T-lymphocytes relating to the subpopulation of suppressor cytotoxic cells.
Novikova
A V
AV
Gazizova
R R
RR
Shershevskaia
A Ia
AIa
Vinogradova
M A
MA
Lobanov
Iu F
IuF
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000276:immunology* / Q000473:pathology; D000937:Antigen-Antibody Reactions / Q000276:immunology*; D001706:Biopsy; D002648:Child; D002908:Chronic Disease; D005455:Fluorescent Antibody Technique; D005753:Gastric Mucosa / Q000276:immunology* / Q000473:pathology; D005756:Gastritis / Q000276:immunology* / Q000473:pathology; D016481:Helicobacter Infections / Q000276:immunology / Q000473:pathology; D016480:Helicobacter pylori; D006801:Humans; D008875:Middle Aged; D011706:Pyloric Antrum
Vozrastnye osobennosti immunnoĭ reaktsii slizistoĭ obolochki antral'nogo otdela zheludka pri khronicheskom gastrite.