title: Antiplatelet aggregation principles of Dendrobium loddigesii.
abstract: The MeOH extract of the stem of Dendrobium loddigesii was found to inhibit the aggregation of rabbit platelets induced by arachidonic acid and collagen. Two active compounds, moscatilin [1] and moscatin [2], were isolated. Moscatilin diacetate [3] also exhibited antiplatelet aggregation activity.
authors.affiliation: National Research Institute of Chinese Medicine, Taipei Hsien, Taiwan.
authors.forename: C C
authors.initials: CC
authors.lastname: Chen
authors.forename: L G
authors.initials: LG
authors.lastname: Wu
authors.forename: F N
authors.initials: FN
authors.lastname: Ko
authors.forename: C M
authors.initials: CM
authors.lastname: Teng
mesh_terms: D000818:Animals; D016718:Arachidonic Acid / Q000037:antagonists & inhibitors / Q000494:pharmacology; D001593:Benzyl Compounds / Q000302:isolation & purification* / Q000494:pharmacology; D003094:Collagen / Q000037:antagonists & inhibitors / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D066298:In Vitro Techniques; D010616:Phenanthrenes / Q000302:isolation & purification* / Q000494:pharmacology; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D011817:Rabbits
chemical_list: D001593:Benzyl Compounds; D004365:Drugs, Chinese Herbal; D010616:Phenanthrenes; D010975:Platelet Aggregation Inhibitors; C091085:moscatin; C071845:dendrophenol; D016718:Arachidonic Acid; D003094:Collagen