title: Late onset absence seizures in multiple sclerosis: a case report.
abstract: A 38-year-old woman was admitted to hospital because of generalized tonic-clonic attacks and late onset absence seizures. EEG and Video-EEG showed 3-4 hz generalized spike and wave discharges lasting 1-8 seconds, which were associated with impairment of consciousness and unresponsiveness. MR scan revealed multiple demyelinating lesions, including the most prominent one in the mesial frontal region that we suppose might be responsible for electroclinical absence seizures. After investigation the diagnosis of multiple sclerosis was made. Possible pathophysiological mechanisms and differential diagnosis of tonic-clonic and absence seizures in MS are discussed.
authors.affiliation: Department of Neurology, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Bolay
authors.forename: H
authors.initials: H
authors.lastname: Ay
authors.forename: S
authors.initials: S
authors.lastname: Saygi
authors.forename: A
authors.initials: A
authors.lastname: Ciğer
authors.forename: O
authors.initials: O
authors.lastname: Saribas
mesh_terms: D000328:Adult; D004569:Electroencephalography; D004832:Epilepsy, Absence / Q000175:diagnosis / Q000209:etiology*; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000150:complications* / Q000175:diagnosis