Islet cell transplantation for insulin-dependent diabetes.
About 20 years after investigators began work on the isolation of animal islets, we are now poised to use such cells to control blood sugar levels in humans. Studies in various laboratories have led to development of transplantation techniques that obviate the need for chronic immunosuppression; equally important, the techniques also appear to avoid the problem of graft rejection.
Lacy
P E
PE
Washington University School of Medicine, St. Louis, USA.
D000818:Animals; D002469:Cell Separation / Q000379:methods; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology / Q000601:surgery*; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007165:Immunosuppression Therapy; D007515:Islets of Langerhans / Q000166:cytology / Q000276:immunology; D016381:Islets of Langerhans Transplantation / Q000276:immunology / Q000379:methods