title: Monostotic Paget's disease involving the calcaneus. Diagnostic and therapeutic problems. Two case-reports.
abstract: The authors report the cases of two patients who had chronic incapacitating heel pain unresponsive to standard therapy. They were both found to have Paget's disease of the calcaneus. The diagnosis was difficult because the typical roentgenological changes required time to develop and because no other sites were involved. Local corticosteroid injections, elimination of weight-bearing, and standard analgesic therapy were ineffective. Bisphosphonate therapy (pamidronate) given as intravenous infusions ensured prompt lasting pain relief, making ambulation possible.
authors.affiliation: Rheumatology Department A, Cochin Teaching Hospital, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Perrot
authors.forename: E
authors.initials: E
authors.lastname: Mortier
authors.forename: M
authors.initials: M
authors.lastname: Renoux
authors.forename: C
authors.initials: C
authors.lastname: Job-Deslandre
authors.forename: C J
authors.initials: CJ
authors.lastname: Menkès
mesh_terms: D002111:Calcaneus / Q000000981:diagnostic imaging; D004164:Diphosphonates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010001:Osteitis Deformans / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000077268:Pamidronate; D014057:Tomography, X-Ray Computed
chemical_list: D004164:Diphosphonates; D000077268:Pamidronate