A physical map encompassing GP2B, EPB3, D17S183, D17S78, D17S1183, and D17S1184.
The q21 region of chromosome 17 contains the gene BRCA1, which is involved in familial early-onset breast and ovarian cancers. A physical map of a region that extends from a distal boundary of the BRCA1 region, D17S78, to GP2B has been constructed. The map consists of 30 STSs, including 2 new short tandem repeat polymorphic markers. The contig is composed of a mixture of 7 YACs, 5 P1 plasmids, and 14 cosmids and was ordered by STS-content mapping.
Miki
Y
Y
Department of Medical Informatics, University of Utah Medical School, Salt Lake City 84108, USA.
Swensen
J J
JJ
Hobbs
M R
MR
DeHoff
B S
BS
Rosteck
P R
PR
Skolnick
M H
MH
Neuhausen
S L
SL
D019313:BRCA1 Protein; D001483:Base Sequence; D001943:Breast Neoplasms / Q000235:genetics; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D002886:Chromosomes, Human, Pair 17; D003001:Cloning, Molecular; D003360:Cosmids; D017931:DNA Primers; D005819:Genetic Markers; D006801:Humans; D008969:Molecular Sequence Data; D009363:Neoplasm Proteins / Q000235:genetics*; D010957:Plasmids; D016133:Polymerase Chain Reaction; D014157:Transcription Factors / Q000235:genetics*
D019313:BRCA1 Protein; D017931:DNA Primers; D005819:Genetic Markers; D009363:Neoplasm Proteins; D014157:Transcription Factors