title: Split skin grafting on severely damaged skin. A technique using absorbable tissue adhesive.
abstract: BACKGROUND
  Patients with severely damaged skin are more likely to develop skin malignancies. However, suturing following excision of tumors is difficult due to their fragile skin.
  
  
  OBJECTIVE
  To evaluate the effectiveness of a technique using butyl-2-cyanoacrylate tissue adhesive in split skin grafts in patients with severely damaged skin.
  
  
  METHODS
  The technique was used in 19 patients with 24 skin tumors. Two patients also had multiple skin biopsies to assess the biodegradability of the adhesive.
  
  
  RESULTS
  Split skin grafts were applied successfully in all patients. The adhesive was completely absorbed without a foreign body reaction within 6 months.
  
  
  CONCLUSIONS
  We recommend the use of butyl-2-cyanoacrylate in split skin grafting patients with severely damaged skin.
authors.affiliation: Department of Dermatology, University Hospital, Queen's Medical Centre, Nottingham, United Kingdom.
authors.forename: I
authors.initials: I
authors.lastname: Zaki
authors.forename: L
authors.initials: L
authors.lastname: Scerri
authors.forename: L
authors.initials: L
authors.lastname: Millard
mesh_terms: D000042:Absorption; D000368:Aged; D001458:Bandages; D001673:Biodegradation, Environmental; D001706:Biopsy; D002280:Basal Cell Carcinoma / Q000532:radiotherapy / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000601:surgery; D004659:Enbucrilate / Q000737:chemistry / Q000493:pharmacokinetics / Q000627:therapeutic use*; D005260:Female; D005549:Foreign-Body Reaction / Q000517:prevention & control; D006488:Hemostasis, Surgical; D006801:Humans; D008297:Male; D011832:Radiation Injuries / Q000473:pathology; D011878:Radiotherapy / Q000009:adverse effects; D012867:Skin / Q000473:pathology* / Q000528:radiation effects; D012878:Skin Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods*; D013472:Sunlight / Q000009:adverse effects
chemical_list: D004659:Enbucrilate