Bioactive terpenoids from Octocorallia, I. Bioactive diterpenoids: litophynols A and B from the mucus of the soft coral Litophyton sp.
Two new eunicellin-type diterpenoids, litophynols A [1] and B [2], and the known diterpenoids litophynins E [3], H [11], and I monoacetate [12], were isolated from the mucus secreted by the soft coral Litophyton sp. Their structures have been elucidated on the basis of spectral and single crystal X-ray analyses. These compounds have hemolytic activity.
Miyamoto
T
T
Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Yamada
K
K
Ikeda
N
N
Komori
T
T
Higuchi
R
R
D000818:Animals; D003063:Cnidaria / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D006461:Hemolysis / Q000187:drug effects*; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009093:Mucus / Q000737:chemistry; D009990:Oryzias; D011817:Rabbits
D004224:Diterpenes; C091075:litophynol A; C091076:litophynol B