Antibiotic-associated hemorrhagic colitis without Clostridium difficile toxin in children.
We describe nine children with antibiotic-associated hemorrhagic colitis without Clostridium difficile toxin. The onset was usually sudden, with severe hematochezia and abdominal cramps. The illness quickly resolved and required no specific treatment except discontinuation of the implicated antibiotic. Early proctosigmoidoscopy was a useful diagnostic adjunct. It appears that antibiotic-associated hemorrhagic colitis is a distinct entity rather than a variant of antibiotic-associated colitis in children.
Kato
S
S
Department of Pediatrics and Pathology, Sendai City Hospital, Japan.
Ebina
K
K
Ozawa
A
A
Naganuma
H
H
Nakagawa
H
H
D000293:Adolescent; D000658:Amoxicillin / Q000009:adverse effects; D000667:Ampicillin / Q000009:adverse effects / Q000031:analogs & derivatives; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000077525:Cefdinir; D002511:Cephalosporins / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003092:Colitis / Q000139:chemically induced*; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013407:Sulbactam / Q000009:adverse effects
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; C035444:sultamicillin; D000667:Ampicillin; D000658:Amoxicillin; C045384:lenampicillin; D000077525:Cefdinir; D013407:Sulbactam