[The action of high-molecular linear polymers on the circulatory system].
An analysis of the hemodynamic consequences of the injections of long linear polymers with high molecular weight is introduced. These injections lead to an increase of the cardiac output, to a decrease of the blood pressure, and hence cause a reduction of the resistance to blood flow. It follows that such kind of polymers is able to normalize hemodynamics under some pathophysiological conditions, e.g., during experimental atherosclerosis, ischemic state, hemorrhagic shock. An addition of drag-reducing polymers into the blood system is associated with a modification of the blood flow microstructure itself.
Grigorian
S S
SS
Sokolova
I A
IA
Shakhnazarov
A A
AA
D000818:Animals; D001775:Blood Circulation / Q000187:drug effects* / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D008970:Molecular Weight; D011108:Polymers / Q000494:pharmacology* / Q000627:therapeutic use
D011108:Polymers
Vozdeĭstvie vysokomolekuliarnykh lineĭnykh polimerov na sistemu krovoobrashcheniia.