Hemodynamic variations between end-to-side and end-organ flap systems.
This study aimed to evaluate microcirculatory differences between anatomic arrangements of the intact side flow and the end flow systems. The cremaster muscle tube-flap model was employed. Fifty male Sprague-Dawley rats were studied in two experimental groups of 25 animals each. The end-to-side vascular system was compared with end-organ flaps during acute (6 hours) and chronic (1, 3, 7, and 14 days) observation periods. Standard microcirculatory measurements were taken in all groups including vessel diameters, red blood cell velocities, and capillary densities. End-to-side flaps presented with stable flow hemodynamics over a 14-day period. In end-organ flaps we found acute venous congestion, alterations in arterial and venous flow velocities, and a significant decline in capillary perfusion.
Siemionow
M
M
University of Utah, Division of Plastic & Reconstructive Surgery, Salt Lake City 84123, USA.
Andreasen
T
T
Lister
G
G
D000009:Abdominal Muscles / Q000098:blood supply* / Q000601:surgery*; D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001783:Blood Flow Velocity; D006439:Hemodynamics; D008297:Male; D008833:Microcirculation / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013524:Surgical Flaps / Q000379:methods*; D013997:Time Factors