title: Genetic hypertension. A direct link to salt.
abstract: The basis of one type of inherited hypertension has been discovered-it is caused by mutations in the gene for the beta subunit of a renal sodium channel.
authors.affiliation: Department of Medicine and Therapeutics, University of Leicester School of Medicine, UK.
authors.forename: B
authors.initials: B
authors.lastname: Leckie
authors.forename: R
authors.initials: R
authors.lastname: Norman
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D016368:Frameshift Mutation; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology; D007668:Kidney / Q000378:metabolism* / Q000502:physiology / Q000503:physiopathology; D046911:Macromolecular Substances; D008961:Models, Structural; D008969:Molecular Sequence Data; D017354:Point Mutation; D012016:Reference Values; D015222:Sodium Channels / Q000737:chemistry / Q000235:genetics*; D013577:Syndrome
chemical_list: D046911:Macromolecular Substances; D015222:Sodium Channels