title: [Role of outdoor and indoor air pollution in the etiology of lung cancer].
abstract: The results of a case-control study of lung cancer risk in female non-smokers in Moscow are presented in the paper. The increase in a risk of lung cancer was found to be associated with outdoor pollution, the closure of the residence to chemical industry and ferrous and non-ferrous smelters, environmental tobacco smoke from husbands and exposure to radon (Rn) at home. The relative risk of lung cancer (RR) for those living in high air polluted versus relatively pure areas was 2.6 (95% CI = 1.2-5.6). RR of lung cancer related to the closure of the residence to chemical industry and ferrous and non-ferrous smelters were 2.0 (95% CI = 1.0-3.9) and 1.75 (95% CI = 1.0-3.1). The analysis has shown that there is an increase in lung cancer risk in women whose husbands smoke, which is as high as 1.9 (95% CI = 1.3-2.9). Lung cancer risk is associated with levels of exposure to Rn in the dwellings: RR was 2.48 (95% CI = 1.4-4.3) for the Rn concentration of > 24.3 Bq/m3 versus < 13 Bq/m3.
authors.forename: D G
authors.initials: DG
authors.lastname: Zaridze
authors.forename: G M
authors.initials: GM
authors.lastname: Zemlianaia
authors.forename: Z N
authors.initials: ZN
authors.lastname: Aĭtakov
mesh_terms: D000230:Adenocarcinoma / Q000139:chemically induced / Q000209:etiology*; D000328:Adult; D000397:Air Pollution / Q000009:adverse effects*; D016902:Air Pollution, Indoor / Q000009:adverse effects*; D002274:Carcinogens, Environmental / Q000009:adverse effects; D018288:Carcinoma, Small Cell / Q000139:chemically induced / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced / Q000209:etiology*; D002617:Chemical Industry; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced / Q000209:etiology*; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D008962:Models, Theoretical; D011886:Radon / Q000009:adverse effects; D014028:Tobacco Smoke Pollution / Q000009:adverse effects
chemical_list: D002274:Carcinogens, Environmental; D014028:Tobacco Smoke Pollution; D011886:Radon
vernacular_title: Rol' zagriazneniia atmosfernogo vozdukha i vozdukha pomeshcheniĭ v étiologii raka legkogo.