Intracranial gangliocytoma in a dog.
The clinical, pathologic, immunohistochemical, and electron microscopic characteristics of a pure intracranial gangliocytoma in a 6-year-old spayed female dog are presented. The tumor is very rare in humans, and has not been previously reported in the dog. The most remarkable feature of this tumor was that it was composed of a single neuronal cell type without the presence of glial elements, as demonstrated by the negative immunohistochemical reaction to glial fibrillary acidic protein.
Nyska
A
A
Department of Pathology, Kimron Veterinary Institute, Beit Dagan, Israel.
Shamir
M H
MH
Harmelin
A
A
Sandbank
J
J
Waner
T
T
D000818:Animals; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D005729:Ganglioneuroma / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D008854:Microscopy, Electron / Q000662:veterinary