title: Expression and selective inhibition of constitutive and inducible forms of cyclooxygenase.
authors.affiliation: G.D. Searle, Monsanto Company, St. Louis, Missouri 63167, USA.
authors.forename: K
authors.initials: K
authors.lastname: Seibert
authors.forename: J
authors.initials: J
authors.lastname: Masferrer
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: K
authors.initials: K
authors.lastname: Leahy
authors.forename: S
authors.initials: S
authors.lastname: Hauser
authors.forename: J
authors.initials: J
authors.lastname: Gierse
authors.forename: C
authors.initials: C
authors.lastname: Koboldt
authors.forename: G
authors.initials: G
authors.lastname: Anderson
authors.forename: M
authors.initials: M
authors.lastname: Bremer
authors.forename: S
authors.initials: S
authors.lastname: Gregory
mesh_terms: D000698:Analgesia; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001169:Arthritis, Experimental / Q000188:drug therapy; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D015870:Gene Expression; D007213:Indomethacin / Q000494:pharmacology / Q000633:toxicity; D007249:Inflammation / Q000201:enzymology; D007527:Isoenzymes / Q000096:biosynthesis* / Q000378:metabolism; D009928:Organ Specificity; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis* / Q000378:metabolism; D011720:Pyrazoles / Q000494:pharmacology / Q000633:toxicity; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis; D012377:Rodentia
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D011720:Pyrazoles; D012333:RNA, Messenger; C090859:1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole; D011451:Prostaglandin-Endoperoxide Synthases; D007213:Indomethacin