title: Lactose malabsorption in Khants in western Siberia.
abstract: BACKGROUND
  We wanted to estimate the prevalence of selective lactose malabsorption (SLM) in Khants, a small Finno-Ugric population living in Western Siberia who have traditionally consumed no milk in adulthood.
  
  
  METHODS
  A total of 80 Khants, aged 8-57 years and living on the middle reaches of the River Ob, were studied. The diagnosis was based on a lactose tolerance test; general malabsorption was excluded by a glucose-galactose tolerance test whenever possible. In six subjects electronmicroscopic examination of the duodenal mucosa was performed.
  
  
  RESULTS
  The prevalence of SLM in the Khants was 94%.
  
  
  CONCLUSIONS
  This is the highest prevalence found in the previous Soviet Union.
authors.affiliation: University of Tartu, Estonia.
authors.forename: M
authors.initials: M
authors.lastname: Lember
authors.forename: A
authors.initials: A
authors.lastname: Tamm
authors.forename: A
authors.initials: A
authors.lastname: Piirsoo
authors.forename: K
authors.initials: K
authors.lastname: Suurmaa
authors.forename: K
authors.initials: K
authors.lastname: Kermes
authors.forename: R
authors.initials: R
authors.lastname: Kermes
authors.forename: T
authors.initials: T
authors.lastname: Sahi
authors.forename: M
authors.initials: M
authors.lastname: Isokoski
mesh_terms: D000328:Adult; D001706:Biopsy; D002648:Child; D004386:Duodenum / Q000473:pathology; D005006:Ethnicity; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007787:Lactose Intolerance / Q000175:diagnosis / Q000208:ethnology*; D007789:Lactose Tolerance Test; D008297:Male; D008854:Microscopy, Electron; D015995:Prevalence; D012800:Siberia / Q000453:epidemiology