Highly polymorphic dinucleotide repeat at the NF2 gene.
A highly polymorphic CA repeat was identified in a cosmid containing the 5' end of the NF2 tumour suppressor gene. This marker has proved useful in presymptomatic diagnosis in affected families.
Bourn
D
D
Department of Human Genetics, University of Newcastle upon Tyne, UK.
Strachan
T
T
D000483:Alleles; D001483:Base Sequence; D016515:Genes, Neurofibromatosis 2 / Q000235:genetics*; D005819:Genetic Markers; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D009363:Neoplasm Proteins / Q000235:genetics*; D016518:Neurofibromatosis 2 / Q000175:diagnosis / Q000235:genetics*; D025581:Neurofibromin 2; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid
D005819:Genetic Markers; D008565:Membrane Proteins; D009363:Neoplasm Proteins; D025581:Neurofibromin 2