title: Peptidergic innervation of the human prostate, seminal vesicle and vas deferens.
abstract: Neuropeptidergic innervation of the human prostate, seminal vesicle and vas deferens was investigated by immunohistochemical methods. The innervation pattern of all organs was very dense. Neuropeptide Y- and tyrosine hydroxylase-positive nerve fibers were most abundant and localized mainly in the smooth muscle layer. On the contrary, vasoactive intestinal polypeptide-positive nerve fibers were mainly found beneath the epithelium. Also leu-enkephaline-, peptide histidine isoleusine- and calcitonin gene-related peptide-positive nerve fibers could be observed in all organs, but somatostatin-positive nerves only in the prostate and seminal vesicle and met-enkephalin- and substance P-positive nerves only in the prostate.
authors.affiliation: Clinic of Surgery, Tampere University Hospital, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Tainio
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000294:innervation / Q000378:metabolism; D009412:Nerve Fibers / Q000502:physiology; D009479:Neuropeptides / Q000502:physiology*; D011467:Prostate / Q000294:innervation* / Q000378:metabolism; D012669:Seminal Vesicles / Q000294:innervation* / Q000378:metabolism; D014649:Vas Deferens / Q000294:innervation* / Q000378:metabolism
chemical_list: D009479:Neuropeptides