Current therapies in motor neurone disease.
Motor neurone disease (MND) is a fatal neurological disorder, characterised by progressive weakness and wasting of muscles. The variety of hypotheses for its aetiopathogenesis are reflected in the large number of drugs tried in an attempt to modify disease progression. Although MND was first described by Charcot in the 1870s, there is as yet no known cure for the disease.
Goonetilleke
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Department of Neurology, North Manchester General Hospital.
D000597:Amino Acids, Branched-Chain / Q000627:therapeutic use*; D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy; D002986:Clinical Trials as Topic; D005732:Gangliosides / Q000627:therapeutic use; D006801:Humans; D016472:Motor Neuron Disease / Q000139:chemically induced / Q000188:drug therapy*; D009498:Neurotoxins / Q000633:toxicity; D013973:Thyrotropin-Releasing Hormone / Q000627:therapeutic use
D000597:Amino Acids, Branched-Chain; D005732:Gangliosides; D009498:Neurotoxins; D013973:Thyrotropin-Releasing Hormone