title: Beneficial effect of growth hormone on atherogenic risk in children with growth hormone deficiency.
abstract: We studied changes in the atherogenic index (total cholesterol divided by high-density lipoprotein cholesterol) in 12 prepubertal boys with growth hormone (GH) deficiency during 9 months of GH treatment. High-density lipoprotein cholesterol level increased until 5 months without significant changes in total cholesterol level; thus GH therapy may be beneficial in reducing the atherogenic index in boys with GH deficiency.
authors.affiliation: Department of Endocrinology and Metabolism, Fukuoka Children's Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kohno
authors.forename: N
authors.initials: N
authors.lastname: Ueyama
authors.forename: S
authors.initials: S
authors.lastname: Yanai
authors.forename: K
authors.initials: K
authors.lastname: Ukaji
authors.forename: S
authors.initials: S
authors.lastname: Honda
mesh_terms: D000293:Adolescent; D001161:Arteriosclerosis / Q000517:prevention & control*; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D013006:Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D008076:Cholesterol, HDL; D011994:Recombinant Proteins; D013006:Growth Hormone; D002784:Cholesterol