title: [The liver transplant program of the Hospital General Universitario Gregorio Marañón: an analysis of the first 100 patients].
abstract: During a 3-year period between 1990 and 1993, 100 patients received orthotopic liver transplantation at the "Gregorio Marañón" University General Hospital. The mean age of the patients was relatively high (46.9 +/- 10 years), with an important number of cirrhotic patients (91%). The rate of primary liver failure was relatively low (4.5% of transplantations) although 12 cases with more than 55 years were included in the present series. Eleven retransplantations were performed, 8 for early failure of the graft and 3 for chronic failure. Postoperative complications of the graft were vascular in 9 cases, biliary in 17 cases, and acute rejection (cellular) in 70 patients, although only 50 of these patients required treatment with steroid boluses. Infections were diagnosed in 60 cases with 80% of major infections, 6 of them caused by Aspergillus fumigatus that were lethal in all the cases. Postoperative survival was 82%, 72%, 69% and 69% at 1 month, 6 months, 1 year and 2 years respectively.
authors.affiliation: Cirugía General y Aparato Digestivo, Hospital General Universitario Giregorio Marañón.
authors.forename: J
authors.initials: J
authors.lastname: Calleja Kempin
authors.forename: G
authors.initials: G
authors.lastname: Clemente Ricote
authors.forename: J
authors.initials: J
authors.lastname: Pérez Ferreiroa
authors.forename: R
authors.initials: R
authors.lastname: Bañares Cañizares
authors.forename: J R
authors.initials: JR
authors.lastname: Polo Melero
authors.forename: J L
authors.initials: JL
authors.lastname: García Sabrido
authors.forename: E
authors.initials: E
authors.lastname: Valdecantos Montes
authors.forename: L
authors.initials: L
authors.lastname: Olmedilla
authors.forename: L
authors.initials: L
authors.lastname: Santos
authors.forename: J
authors.initials: J
authors.lastname: Pérez Peña
mesh_terms: D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006769:Hospitals, General / Q000706:statistics & numerical data*; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D007165:Immunosuppression Therapy; D008107:Liver Diseases / Q000175:diagnosis / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D013030:Spain / Q000453:epidemiology; D014019:Tissue Donors
vernacular_title: Programa de trasplante hepático del Hospital General Universitario Gregorio Marañón: análisis de los 100 primeros pacientes.