title: [Diphosphonates in the treatment of osteoporosis and in the prevention of associated fractures].
abstract: Diphosphonates are capable to increase vertebral bone mineral mass in postmenopausal osteoporosis. Because the risk of fractures is related to the reduction of bone mass, the positive effect of diphosphonates most probably produced a decrease in fracture rate. At present these drugs represent a rational option for the treatment of postmenopausal osteoporosis.
authors.affiliation: Clinica Ortopedica, Università degli Studi di Messina.
authors.forename: M
authors.initials: M
authors.lastname: De Gregorio
authors.forename: G
authors.initials: G
authors.lastname: De Gregorio
mesh_terms: D016723:Bone Remodeling / Q000187:drug effects; D004164:Diphosphonates / Q000627:therapeutic use*; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy*
chemical_list: D004164:Diphosphonates
vernacular_title: I bifosfonati nel trattamento dell'osteoporosi e nella prevenzione delle fratture correlate.