[A case of mitral valve replacement with chronic idiopathic thrombocytopenic purpura after high-dose immunoglobulin infusion].
A 60-year-old female patient diagnosed as having mitral stenosis with chronic idiopathic thrombocytopenic purpura (ITP), with a platelet count of 6.8 x 10(4)/mm3, was scheduled to undergo mitral valve replacement. High-dose immunoglobulin infusion (400 mg/kg/day for five days) was begun four days before the operation and increased the platelet count to 9.1 x 10(4)/mm3 just before the operation. Intraoperative hemostasis was excellent, and the postoperative course was uneventful. High-dose immunoglobulin therapy appears to be a first choice for controlling hemorrhagic tendency in ITP patients undergoing heart surgery.
Sato
M
M
Department of Cardiovascular Surgery, Hiroo Cosmopolitan Hospital, Tokyo, Japan.
Konno
S
S
Maemura
T
T
Goto
K
K
Hayashibe
Y
Y
Ito
J
J
D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000601:surgery*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000628:therapy*
D016756:Immunoglobulins, Intravenous