title: Familial thrombocytosis.
abstract: Four cases of thrombocytosis in three successive generations of a family are described. High peripheral platelet count was found incidentally in the proband with cutaneous malignant lymphoma. Bone marrow examination showed megakaryocytic hyperplasia. Neither Philadelphia chromosome nor chimaeric bcr/abl junction was detected in marrow cells. In this family, thrombocytosis was thought to be transmitted by an autosomal dominant mode of inheritance.
authors.affiliation: Department of Paediatrics, Hitachi General Hospital, Ibaraki, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kikuchi
authors.forename: T
authors.initials: T
authors.lastname: Tayama
authors.forename: H
authors.initials: H
authors.lastname: Hayakawa
authors.forename: I
authors.initials: I
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Hoshino
authors.forename: A
authors.initials: A
authors.lastname: Ohsaka
mesh_terms: D002675:Child, Preschool; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D010375:Pedigree; D013922:Thrombocytosis / Q000235:genetics*