title: Indomethacin in controlling "normal perfusion pressure breakthrough" in a case of large cerebral arteriovenous malformation.
abstract: Control of "normal perfusion pressure breakthrough" is difficult and controversial. We describe a case in which indomethacin was used with success. We recommend extensive cerebral monitoring including regional cerebral oximetry when using indomethacin to detect impending cerebral ischemia.
authors.affiliation: Department of Anesthesia, Aalborg Hospital, Denmark.
authors.forename: P A
authors.initials: PA
authors.lastname: Hansen
authors.forename: F
authors.initials: F
authors.lastname: Knudsen
authors.forename: M
authors.initials: M
authors.lastname: Jacobsen
authors.forename: J
authors.initials: J
authors.lastname: Haase
authors.forename: N
authors.initials: N
authors.lastname: Bartholdy
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000517:prevention & control; D002560:Cerebrovascular Circulation / Q000187:drug effects; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000601:surgery / Q000628:therapy; D007427:Intracranial Pressure / Q000187:drug effects*; D016343:Monitoring, Intraoperative; D010100:Oxygen / Q000097:blood; D011559:Pseudotumor Cerebri / Q000188:drug therapy*
chemical_list: D010100:Oxygen; D007213:Indomethacin