Acute lymphoblastic transformation of essential thrombocythaemia.
Essential thrombocythaemia is a myeloproliferative disorder which may transform to acute myeloid leukaemia, especially following therapy with alkylating agents or radioactive phosphorus. We describe the rare occurrence of acute lymphoblastic leukaemia transformation in a patient with known essential thrombocythaemia.
Murphy
P T
PT
Haematology Department, Leicester Royal Infirmary.
Sivakumaran
M
M
van Rhee
F
F
Watmore
A E
AE
Mitchell
V E
VE
D006801:Humans; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000209:etiology*; D013920:Thrombocythemia, Essential / Q000150:complications*