Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe.
Vesell
E S
ES
Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey 17033, USA.
Seaton
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TD
A-Rahim
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YI
D000328:Adult; D002753:Chlorzoxazone / Q000031:analogs & derivatives / Q000097:blood / Q000378:metabolism* / Q000493:pharmacokinetics / Q000652:urine; D019392:Cytochrome P-450 CYP2E1; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D015335:Molecular Probes; D010089:Oxidoreductases, N-Demethylating / Q000235:genetics* / Q000378:metabolism*
D015335:Molecular Probes; C039289:6-hydroxychlorzoxazone; D003577:Cytochrome P-450 Enzyme System; D019392:Cytochrome P-450 CYP2E1; D010089:Oxidoreductases, N-Demethylating; D002753:Chlorzoxazone