Superantigens. Gazing into the crystal ball.
The recently determined crystal structures of complexes between bacterial toxin 'superantigens' and MHC class II molecules shed light on the nature of the interactions between these two molecules.
Hsu
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Sackler School of Graduate Biomedical Sciences, Department of Pathology, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
Huber
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D001427:Bacterial Toxins; D018360:Crystallography, X-Ray / Q000379:methods; D004768:Enterotoxins / Q000737:chemistry / Q000378:metabolism; D015798:HLA-DR1 Antigen / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D046911:Macromolecular Substances; D008961:Models, Structural; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D013211:Staphylococcus aureus; D018089:Superantigens / Q000737:chemistry* / Q000378:metabolism
D001427:Bacterial Toxins; D004768:Enterotoxins; D015798:HLA-DR1 Antigen; D046911:Macromolecular Substances; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; C031818:enterotoxin B, staphylococcal