title: Subperiosteal behaviour of alginate and cellulose wound dressing materials.
abstract: A histological comparison was undertaken of the tissue response to a new sodium calcium alginate material (Kaltostat) and an oxidized regenerated cellulose wound dressing (Surgicel) when implanted between bone and periosteum in the jaws at intervals of up to 24 wk. Both biomaterials caused a foreign body reaction, persisting up to 12 wk after surgery. New bone formation occurred along the surface of the mandible in some specimens, but was not apparently related to the implants. It was concluded that the implantation of Kaltostat or Surgicel between bone and periosteum in the jaws caused a delay in wound healing, and had no effect on bone induction.
authors.affiliation: Units of Oral Surgery, University of Birmingham, School of Dentistry, St. Chad's Queensway, UK.
authors.forename: I R
authors.initials: IR
authors.lastname: Matthew
authors.forename: R M
authors.initials: RM
authors.lastname: Browne
authors.forename: J W
authors.initials: JW
authors.lastname: Frame
authors.forename: B G
authors.initials: BG
authors.lastname: Millar
mesh_terms: D000464:Alginates / Q000009:adverse effects*; D000818:Animals; D001458:Bandages / Q000009:adverse effects / Q000592:standards; D001846:Bone Development / Q000187:drug effects; D002482:Cellulose / Q000737:chemistry; D002483:Cellulose, Oxidized / Q000009:adverse effects*; D003760:Dental Impression Materials / Q000009:adverse effects; D004285:Dogs; D005549:Foreign-Body Reaction / Q000139:chemically induced*; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D008297:Male; D008334:Mandible; D009061:Mouth Mucosa / Q000187:drug effects / Q000473:pathology / Q000648:ultrastructure; D010521:Periosteum / Q000187:drug effects*; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology
chemical_list: D000464:Alginates; D002483:Cellulose, Oxidized; D003760:Dental Impression Materials; D006603:Hexuronic Acids; C013695:Surgicel; D020723:Glucuronic Acid; D002482:Cellulose