Colposcopically directed biopsy and loop excision of the transformation zone. Comparison of histologic findings.
We performed a retrospective comparison between the findings from colposcopically directed biopsies and those from loop excision of the transformation zone (LETZ) specimens. The correlation was satisfactory. When a low grade squamous intraepithelial lesion (SIL) was predicted on a cytologic smear and biopsy specimen, no cases of invasive carcinoma were found. In two (0.8%) cases in which a high grade SIL was predicted on the cervical smear and biopsy, microinvasive carcinoma was found in the LETZ specimen.
Ang
M S
MS
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA.
Kaufman
R H
RH
Adam
E
E
Riddle
G
G
Irwin
J F
JF
Reeves
K O
KO
Simon
T L
TL
D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D003127:Colposcopy / Q000379:methods; D004564:Electrocoagulation / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery; D014626:Vaginal Smears / Q000379:methods; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000601:surgery