Malignant melanotic neuroectodermal tumor of infancy.
A 2-month-old boy underwent surgery for removal of a right temporal melanotic neuroectodermal tumor of infancy (MNTI). Histologically the tumor tissue showed signs of malignancy. The child was reexamined several times up to the age of 5 years. Neuroradiological evaluation showed no evidence of tumor recurrence or metastases. No resulting handicap was observed during neurological and psychological follow-up examination at the age of 5 years. Our findings confirm that surgical removal as the therapy of choice provides an excellent prognosis for this kind of tumor in spite of its histologically malignant appearance.
Dammann
O
O
Kinderklinik und Poliklinik, Universitäts-Krankenhaus Eppendorf, Hamburg, Germany.
Hagel
C
C
Allers
B
B
Grubel
G
G
Schulte
F J
FJ
D001921:Brain / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009336:Necrosis / Q000473:pathology; D017600:Neuroectodermal Tumor, Melanotic / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D011379:Prognosis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome