Positron emission tomography in the diagnosis and management of coronary artery disease.
Positron emission tomography has grown rapidly from a little-understood research tool into an exciting noninvasive method for the clinician to evaluate myocardial perfusion, metabolism, and cell-membrane function. There are three radionuclides that are currently being used widely in cardiac positron emission tomography. These are nitrogen-13 ammonia, rubidium-82, and fluorine-18 fluordeoxyglucose. Nitrogen-13 ammonia and rubidium-82 are used to assess the severity and location of coronary artery disease, while fluorine-18 fluordeoxyglucose can identify impaired but viable myocardium, thus aiding in the subsequent management of these patients.
Bratton
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Dept of Medicine, LSU Medical Center, Shreveport 71130, USA.
D000641:Ammonia; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D003847:Deoxyglucose / Q000031:analogs & derivatives; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D009206:Myocardium / Q000378:metabolism; D009590:Nitrogen Radioisotopes; D012414:Rubidium Radioisotopes; D014055:Tomography, Emission-Computed
D005462:Fluorine Radioisotopes; D009590:Nitrogen Radioisotopes; D012414:Rubidium Radioisotopes; D019788:Fluorodeoxyglucose F18; D000641:Ammonia; D003847:Deoxyglucose