title: Metachronous small-bowel adenocarcinoma in celiac sprue.
abstract: Celiac sprue, or nontropical sprue, is associated with an increased incidence of digestive tract malignancy. We report a patient with celiac sprue who developed two primary adenocarcinomas of the jejunum > 2 years apart. The second cancer was asymptomatic and detected by surveillance computed tomography. Small-bowel cancers are unusual, and frequency of follow-up has not been established, so that it is important to have a high index of suspicion for these malignancies in celiac patients with vague gastrointestinal symptoms.
authors.affiliation: Department of General Surgery, Yale University of School of Medicine, New Haven, CT 06510, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Begos
authors.forename: S
authors.initials: S
authors.lastname: Kuan
authors.forename: J
authors.initials: J
authors.lastname: Dobbins
authors.forename: T S
authors.initials: TS
authors.lastname: Ravikumar
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D002446:Celiac Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D007580:Jejunal Neoplasms / Q000150:complications* / Q000473:pathology; D007583:Jejunum / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology