title: Experimental dental caries on gnotobiotic inbred mice.
abstract: The purpose of this study in mono-infected gnotobiotic BALB/cA and C3H/HeN mice was to evaluate the cariogenicity of Enterococcus faecalis. The caries incidence and mean caries score in the BALB/cA mice were significantly higher than those in the C3H/HeN. In both of the mouse strains, the mean number of E. faecalis isolated from the cecum content was almost the same, however, the mean number of E. faecalis from the maxilla of BALB/cA was significantly higher than that of C3H/HeN. These results indicate that C3H/HeN has some factors that prevent E. faecalis from attaching to the tooth surfaces.
authors.affiliation: Department of Bacteriology, School of Dental Medicine, Tsurumi University, Kanagawa, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Maeda
authors.forename: S
authors.initials: S
authors.lastname: Arai
authors.forename: A
authors.initials: A
authors.lastname: Ozaki
authors.forename: T
authors.initials: T
authors.lastname: Oowada
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Fujita
authors.forename: T
authors.initials: T
authors.lastname: Mizutani
mesh_terms: D000818:Animals; D002432:Cecum / Q000382:microbiology; D003731:Dental Caries / Q000382:microbiology*; D004195:Disease Models, Animal; D013293:Enterococcus faecalis / Q000472:pathogenicity*; D005856:Germ-Free Life; D051379:Mice; D008807:Mice, Inbred BALB C / Q000382:microbiology; D008809:Mice, Inbred C3H / Q000382:microbiology; D008963:Molar / Q000382:microbiology; D009055:Mouth / Q000382:microbiology; D013045:Species Specificity