title: Production of the staurosporine aglycon K-252c with a blocked mutant of the staurosporine producer strain Streptomyces longisporoflavus and by biotransformation of staurosporine with Streptomyces mediocidicus ATCC 13279.
authors.affiliation: Ciba-Geigy AG, Pharmaceutical Division, Basel, Switzerland.
authors.forename: K
authors.initials: K
authors.lastname: Goeke
authors.forename: P
authors.initials: P
authors.lastname: Hoehn
authors.forename: O
authors.initials: O
authors.lastname: Ghisalba
mesh_terms: D000470:Alkaloids / Q000378:metabolism*; D002227:Carbazoles / Q000378:metabolism*; D026121:Indole Alkaloids; D009154:Mutation; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*; D019311:Staurosporine; D013302:Streptomyces / Q000378:metabolism
chemical_list: D000470:Alkaloids; D002227:Carbazoles; D026121:Indole Alkaloids; C049985:staurosporine aglycone; D011493:Protein Kinase C; D019311:Staurosporine