title: Analgesia following day-case knee arthroscopy--the effect of piroxicam with or without bupivacaine infiltration.
abstract: Sixty patients presenting for day-case arthroscopy of the knee under general anaesthesia were studied. Patients were randomly allocated to receive, in addition to intramuscular piroxicam 20 mg, either bupivacaine 0.25% 20 ml applied locally to the knee at the end of the procedure (n = 30) or no further intra-operative analgesia (n = 30). Visual analogue pain scores were significantly lower at 1, 2 and 4 h postoperatively in the bupivacaine group (p < 0.05). A higher proportion of patients in the piroxicam-only group required supplemental analgesia before discharge from hospital. The combination of piroxicam and bupivacaine provided superior analgesia to piroxicam alone.
authors.affiliation: Department of Anaesthetics, Queen's University, Belfast, Northern Ireland.
authors.forename: B C
authors.initials: BC
authors.lastname: Morrow
authors.forename: K R
authors.initials: KR
authors.lastname: Milligan
authors.forename: B V
authors.initials: BV
authors.lastname: Murthy
mesh_terms: D000328:Adult; D000698:Analgesia / Q000379:methods; D001182:Arthroscopy; D002045:Bupivacaine / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D010894:Piroxicam / Q000627:therapeutic use*; D011182:Postoperative Care / Q000379:methods
chemical_list: D010894:Piroxicam; D002045:Bupivacaine