Intrathymic injection of donor splenocytes plus systemic antilymphocyte serum or antilymphocyte serum alone prolongs cardiac allograft survival and inhibits graft arteriosclerosis in the Lewis-to-F344 chronic rejection model.
Shin
Y T
YT
Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Adams
D H
DH
Wyner
L R
LR
Akalin
E
E
Sayegh
M H
MH
Karnovsky
M J
MJ
D000818:Animals; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D002908:Chronic Disease; D003324:Coronary Artery Disease / Q000517:prevention & control; D006083:Graft Occlusion, Vascular / Q000517:prevention & control*; D006084:Graft Rejection / Q000517:prevention & control; D006085:Graft Survival; D016027:Heart Transplantation / Q000276:immunology*; D007165:Immunosuppression Therapy / Q000379:methods*; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344; D011917:Rats, Inbred Lew; D013154:Spleen / Q000276:immunology; D013950:Thymus Gland / Q000276:immunology; D014019:Tissue Donors
D000961:Antilymphocyte Serum