Familial thrombocytosis.
Four cases of thrombocytosis in three successive generations of a family are described. High peripheral platelet count was found incidentally in the proband with cutaneous malignant lymphoma. Bone marrow examination showed megakaryocytic hyperplasia. Neither Philadelphia chromosome nor chimaeric bcr/abl junction was detected in marrow cells. In this family, thrombocytosis was thought to be transmitted by an autosomal dominant mode of inheritance.
Kikuchi
M
M
Department of Paediatrics, Hitachi General Hospital, Ibaraki, Japan.
Tayama
T
T
Hayakawa
H
H
Takahashi
I
I
Hoshino
H
H
Ohsaka
A
A
D002675:Child, Preschool; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D010375:Pedigree; D013922:Thrombocytosis / Q000235:genetics*