title: [Estimation of respiratory functions by analysis of expired gas and blood gas during artificial ventilation and general anesthesia].
abstract: One-hundred and seven patients undergoing elective surgery were studied to analyze the correlations between preoperative spirometric values and respiratory parameters during general anesthesia. They were grouped according to 3 criterions; preoperative %VC of less than 80%, FEV1.0% of less than 70%, V50/V25 exceeding 4.0. Following the induction of general anesthesia and of mechanical ventilation, expiratory flow (VE), FECO2, PaCO2 and PaO2 were measured to calculate respiratory parameters including VCO2-SR, VD/VT-Bohr, VD/VT-physiological (phys), a-ETDCO2, Volume Pressure Index (VPI) and A-aDO2. Six respiratory parameters were compared between the groups, and correlations between preoperative spirometric values were studied. Those with lower %VC had higher values in VCO2-SR and in VPI, and those with lower FEV1.0% had higher values in VCO2-SR, in VD/VT-phys and in a-ETDCO2. Significant correlations were also observed between these parameters. Preoperative V50/V25 and A-aDO2 during general anesthesia did not correlate with any of the parameters studied. We conclude that VCO2-SR, VD/VT-phys, a-ETDCO2 and VPI during general anesthesia are useful to detect the patients with restrictive and/or obstructive lung dysfunction, although they are not sensitive enough to detect those with small airway disease.
authors.affiliation: Emergency Clinic, Ehime University School of Medicine.
authors.forename: G
authors.initials: G
authors.lastname: Ochi
authors.forename: Y
authors.initials: Y
authors.lastname: Takasaki
authors.forename: T
authors.initials: T
authors.lastname: Fujitani
authors.forename: Y
authors.initials: Y
authors.lastname: Nakashita
authors.forename: K
authors.initials: K
authors.lastname: Dote
authors.forename: T
authors.initials: T
authors.lastname: Nagaro
authors.forename: T
authors.initials: T
authors.lastname: Arai
mesh_terms: D000368:Aged; D000768:Anesthesia, General; D001784:Blood Gas Analysis; D001944:Breath Tests; D002245:Carbon Dioxide / Q000032:analysis; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D008173:Lung Diseases, Obstructive / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D012121:Respiration, Artificial; D012129:Respiratory Function Tests
chemical_list: D002245:Carbon Dioxide