title: A transcript family from a long-range repeat cluster of the house mouse.
abstract: A family of closely related genes is a component of the polymorphic long-range repeat cluster D1Lub1 of the house mouse. Members of the gene family have diverged from one another by rearrangements and point mutations. D1Lub1 cluster have low (approximately 50) or high (> or = 500) copy numbers. In mice with high-copy clusters five or six poly(A)+ RNAs are found, while in mice with low-copy clusters only a single member of the RNA family is detected. The RNA family is synthesized in a tissue-independent manner. Each member of the RNA family is defined by a set of DNA probes. Cross hybridization with the probes reveals common 5' regions and variable remaining parts. The RNA variants are probably transcribed from different gene copies.
authors.affiliation: Institut für Biologie, Medizinische Universität zu Lübeck, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Weichenhan
authors.forename: B
authors.initials: B
authors.lastname: Kunze
authors.forename: C
authors.initials: C
authors.lastname: Plass
authors.forename: T
authors.initials: T
authors.lastname: Hellwig
authors.forename: H
authors.initials: H
authors.lastname: Winking
authors.forename: W
authors.initials: W
authors.lastname: Traut
mesh_terms: D000818:Animals; D000835:Animals, Wild / Q000235:genetics; D001923:Brain Chemistry; D015342:DNA Probes; D005858:Germany; D008297:Male; D051379:Mice / Q000235:genetics*; D008810:Mice, Inbred C57BL; D005810:Multigene Family; D009132:Muscles / Q000737:chemistry; D010802:Phylogeny; D012333:RNA, Messenger / Q000235:genetics* / Q000302:isolation & purification; D012091:Repetitive Sequences, Nucleic Acid; D013548:Sweden; D013737:Testis / Q000737:chemistry; D014781:Viscera / Q000737:chemistry
chemical_list: D015342:DNA Probes; D012333:RNA, Messenger