Gestational trophoblastic tumors of the uterus: MR imaging--pathologic correlation.
The purpose of this study is to evaluate the MR findings of gestational trophoblastic tumors (GTTs). Ten patients who confirmed the diagnosis (4 choriocarcinomas and 6 invasive moles) constituted the basis of our study. The MR findings from these patients were prospectively correlated with the histopathology of resected tumor specimens. MR findings of 4 patients with choriocarcinomas were well-defined, hemorrhagic masses with central necrosis. In contrast, 6 patients with invasive moles showed ill-defined, permeative masses with densely enhanced solid components and tiny cystic lesions. The trophoblastic proliferation, coagulation necrosis, and molar villi had varying signal intensities on T1- and T2-weighted images. Our results suggest that MR imaging is a promising tool for noninvasive morphologic analysis of GTTs.
Ha
H K
HK
Department of Radiology, Catholic University Medical College, Seoul, Korea.
Jung
J K
JK
Jee
M K
MK
Kim
H H
HH
Lee
J M
JM
Nam-Koong
S E
SE
Kim
S J
SJ
D000328:Adult; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011247:Pregnancy; D011446:Prospective Studies; D014328:Trophoblastic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery