title: Primary malignant lymphoma of the liver associated with cirrhosis induced by hepatitis C viral infection.
abstract: We present a case of primary malignant lymphoma of the liver of B cell origin with cirrhosis induced by hepatitis C viral infection. A 75-year-old Japanese woman with chronic liver dysfunction was admitted for hepatic tumors. The tumors were hypoechoic on ultrasonography and hypodense on computed tomography. Antibody to hepatitis C virus was positive. Ultrasonically guided biopsy was performed, and we diagnosed hepatic lymphoma with cirrhosis induced by hepatitis C virus clinically and immunohistochemically. This case may be the first report of the association of these two diseases, and may provide additional evidence of a predisposition to malignancy in cirrhosis.
authors.affiliation: Department of Internal Medicine, Koseiren Kamo Hospital, Aichi.
authors.forename: K
authors.initials: K
authors.lastname: Morita
authors.forename: H
authors.initials: H
authors.lastname: Hoshino
authors.forename: J
authors.initials: J
authors.lastname: Imada
authors.forename: N
authors.initials: N
authors.lastname: Yoshida
authors.forename: D
authors.initials: D
authors.lastname: Nishimura
authors.forename: N
authors.initials: N
authors.lastname: Katada
authors.forename: H
authors.initials: H
authors.lastname: Sano
authors.forename: K
authors.initials: K
authors.lastname: Kato
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D016174:Hepacivirus; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000628:therapy / Q000821:virology; D008113:Liver Neoplasms / Q000150:complications* / Q000628:therapy / Q000821:virology; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000628:therapy / Q000821:virology