Taste evaluations of angiotensin I converting enzyme inhibitors, Leu-Lys-Tyr analogues.
Tastes of Leu-Lys-Tyr (LKY) analogues, a series of potent angiotensin I converting enzyme (ACE) inhibitory peptides were evaluated. Some of these analogues were found to be sweet, such as Val-Lys-Tyr and Ala-Orn-Tyr. Furthermore, the structural requirements for sweetness or decreasing the bitterness were investigated by considerations of the structure-taste relationship with LKY analogues.
Kawakami
A
A
United Graduate School of Agricultural Science, Gifu University, Japan.
Kayahara
H
H
Tadasa
K
K
D000595:Amino Acid Sequence; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013649:Taste
D000806:Angiotensin-Converting Enzyme Inhibitors; D009842:Oligopeptides