Neuromuscular development in Drosophila: insights from embryos and pupae.
During embryogenesis, Drosophila melanogaster generates a set of muscles and motoneurons that are restructured during pupal metamorphosis to give rise to an adult motor system. The study of neuromuscular development in embryos and pupae has recently revealed important insights into the cellular and molecular mechanisms controlling both muscle patterning and the establishment of synaptic connections.
Fernandes
J
J
Biology Department, Yale University, New Haven, Connecticut 06520-8103, USA.
Keshishian
H
H
D000818:Animals; D001369:Axons / Q000502:physiology; D004331:Drosophila melanogaster / Q000196:embryology / Q000254:growth & development*; D047108:Embryonic Development; D009046:Motor Neurons / Q000502:physiology; D024510:Muscle Development; D009469:Neuromuscular Junction / Q000254:growth & development*; D011679:Pupa / Q000254:growth & development*; D013569:Synapses / Q000502:physiology