title: [Benign cutaneous lymphocytoma of the breast areola and Erythema chronicum migrans: a pathognomonic association of Lyme disease].
abstract: BACKGROUND
  Clinical manifestations of Lyme disease are mainly cutaneous, neurologic, cardiac and/or located joints. Some dermatologic manifestations are more specific.
  
  
  METHODS
  An eight year-old-girl was examined because she suffered from a nodular lesion located on the left breast areola which appeared 3 months earlier. This lesion was associated with an expanding erythematous annular lesion located on the anterior face of thorax and left axillary area, without any lymphadenopathy. The association of this cutaneous lymphocytoma and erythema chronicum migrans was suggestive of Borellia infection despite absence of previous tick bite. Serologic tests (indirect immunofluorescence) were negative, but both lesions disappeared within 2 weeks with ceftriaxone, 50 mg/kg/day.
  
  
  CONCLUSIONS
  This association is pathognomonic of Lyme disease; serologic tests may be found negative in the early stages of disease.
authors.affiliation: Unité de dermatologie pédiatrique, hôpital Pellegrin-Enfants, Bordeaux, France.
authors.forename: C
authors.initials: C
authors.lastname: Gautier
authors.forename: B
authors.initials: B
authors.lastname: Vignolly
authors.forename: A
authors.initials: A
authors.lastname: Taïeb
mesh_terms: D001940:Breast; D001943:Breast Neoplasms / Q000150:complications* / Q000188:drug therapy; D002443:Ceftriaxone / Q000627:therapeutic use; D002648:Child; D015787:Erythema Chronicum Migrans / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy; D008193:Lyme Disease / Q000175:diagnosis*; D009558:Nipples; D012878:Skin Neoplasms / Q000150:complications* / Q000188:drug therapy
chemical_list: D002443:Ceftriaxone
vernacular_title: Lymphocytome cutané bénin de l'aréole mamelonnaire et Erythema chronicum migrans: une association pathognomonique de borréliose.