title: Renal biopsy in children: indications, technique and efficacy in 119 consecutive cases.
abstract: Consecutive renal biopsies were performed on native kidneys in 109 children and adolescents, aged 0.1-19.8 (mean 9.9) years (119 biopsies). Bleeding diatheses were excluded or treated pre-operatively with intravenous desmopressin acetate. Biopsies were performed by a radiologist under ultrasound imaging, using an automated spring-loaded device allowing selection of the length of the needle movement and score size. Diagnostically adequate tissue was retrieved in 118 of 119 (99.2%) biopsy procedures; 24-h post-biopsy ultrasonography disclosed a small haematoma of the biopsied kidney in 26% of the cases. No correlation was seen between the occurrence of haematoma and (treated) prolonged bleeding time or a decrease in the haemoglobin level. No major complications occurred. Newly developed macroscopic haematuria was reported by 7% and micturition pain by 7% of patients. Painful body movements were reported by 37%. We conclude that the use of ultrasound imaging and an automated gunshot technique is a safe and efficient method for performing renal biopsies in paediatric patients.
authors.affiliation: Department of Paediatrics, Karolinska Institute, Huddinge Hospital, Sweden.
authors.forename: A B
authors.initials: AB
authors.lastname: Bohlin
authors.forename: S
authors.initials: S
authors.lastname: Edström
authors.forename: B
authors.initials: B
authors.lastname: Almgren
authors.forename: G
authors.initials: G
authors.lastname: Jaremko
authors.forename: H
authors.initials: H
authors.lastname: Jorulf
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy / Q000009:adverse effects* / Q000379:methods; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology*; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D008297:Male; D014463:Ultrasonography