title: [An evaluation of the efficacy of chronotheray with heparin and kurantil in patients with chronic pyelonephritis].
abstract: The effectiveness of traditional therapy (TT) and chronotherapy (CT) with heparin and curantyl was comparatively studied in 80 patients suffering from chronic pyelonephritis. The blood clotting variables were determined every 4 hours before and 2.5-3 weeks after TT and CT in combination with antibacterial therapy. The findings suggest that CT is more effective than TT with heparin and curantyl. With CT, steady-state clinical effects, positive dynamics of laboratory findings and a greater trend to normalization of the circadian organization of hemocoagulation were achieved in earlier periods when lower daily and course doses of the agents were used.
authors.forename: R M
authors.initials: RM
authors.lastname: Zaslavskaia
authors.forename: R T
authors.initials: RT
authors.lastname: Agzamova
authors.forename: T M
authors.initials: TM
authors.lastname: Teĭblium
mesh_terms: D001780:Blood Coagulation Tests; D002908:Chronic Disease; D002940:Circadian Rhythm / Q000187:drug effects*; D004176:Dipyridamole / Q000008:administration & dosage*; D004341:Drug Evaluation; D005260:Female; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D011704:Pyelonephritis / Q000097:blood / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D004176:Dipyridamole; D006493:Heparin
vernacular_title: Otsenka éffektivnosti khronoterapii geparinom i kurantilom bol'nykh khronicheskim pielonefritom.