[The effect of thyroid and gonadal hormones on the chromosomal integrity of liver cells].
The materials presented as well as the data of the author's previous investigations indicate different cytogenetic importance of the basic hormones of the thyroid and sexual glands (thyroxine, testosterone, and estradiol) when they are used in physiologic doses. Thyroxine possesses mutagenic and antimutagenic properties, testosterone possesses only mutagenic ones, while estradiol has no effect on chromosome integrity.
Timchenko
O I
OI
D000818:Animals; D002869:Chromosome Aberrations; D004305:Dose-Response Relationship, Drug; D004958:Estradiol / Q000031:analogs & derivatives* / Q000494:pharmacology; D006498:Hepatectomy; D008099:Liver / Q000187:drug effects* / Q000528:radiation effects / Q000648:ultrastructure; D008297:Male; D051381:Rats; D013739:Testosterone / Q000494:pharmacology*; D013974:Thyroxine / Q000494:pharmacology*; D013997:Time Factors; D014916:Whole-Body Irradiation
D013739:Testosterone; D004958:Estradiol; C023482:estradiol dipropionate; D013974:Thyroxine
Vliianie nekotorykh gormonov shchitovidnoĭ zhelezy i gonad na tselostnost' khromosom kletok pecheni.