Rabbit renal proximal tubule suspensions as a model for nephrotoxicity evaluation of native or in situ metabolized beta-lactam antibiotics.
Dutertre-Catella
H
H
Laboratoire de Toxicologie (EA 207), Faculté de Pharmacie, Paris, France.
Martin
C
C
Debray
M
M
Pham-Huy
C
C
Thevenin
M
M
Warnet
J M
JM
Podevin
R A
RA
Claude
J R
JR
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D002509:Cephaloridine / Q000633:toxicity; D015377:Cilastatin / Q000494:pharmacology; D004734:Energy Metabolism / Q000187:drug effects; D005260:Female; D005978:Glutathione / Q000378:metabolism; D015378:Imipenem / Q000633:toxicity; D066298:In Vitro Techniques; D007674:Kidney Diseases / Q000139:chemically induced / Q000201:enzymology / Q000378:metabolism*; D007687:Kidney Tubules, Proximal / Q000201:enzymology / Q000378:metabolism*; D011817:Rabbits
D000900:Anti-Bacterial Agents; D015377:Cilastatin; D015378:Imipenem; D000251:Adenosine Triphosphatases; D005978:Glutathione; D002509:Cephaloridine