title: Laparoscopy in the management of patients with cancer of the gastric cardia and oesophagus.
abstract: The role of laparoscopy in determining suitability for resection was prospectively evaluated in 244 patients with cancer of the gastric cardia and oesophagus. Laparoscopy enabled detection of inoperable disease in 92 patients (38 per cent), several of whom had more than one contraindication to surgery. Hepatic metastases (n = 75, 31 per cent), extensive peritoneal (n = 25, 10 per cent) or lymph node involvement (n = 5, 2 per cent) and direct invasion of the liver or colon (n = 5, 2 per cent) were considered contraindications to surgery. Laparoscopy was poorly tolerated in a further 11 (5 per cent) patients, who were not considered suitable for resection. Extra-abdominal metastatic disease was detected in 17 patients who appeared normal at laparoscopy, and a further six patients refused surgery. The remaining 118 patients underwent laparotomy with a view to resection which was successful in 85 (72 per cent). Laparoscopy thus prevented ill-advised laparotomy in 103 patients (42 per cent), either because of extensive intra-abdominal disease or poor tolerance to anaesthesia. Laparoscopy may be a valuable investigation when used to assess the feasibility of resection.
authors.affiliation: University Department of Surgery, Royal Infirmary, Glasgow, UK.
authors.forename: R G
authors.initials: RG
authors.lastname: Molloy
authors.forename: J S
authors.initials: JS
authors.lastname: McCourtney
authors.forename: J R
authors.initials: JR
authors.lastname: Anderson
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D002299:Cardia; D004938:Esophageal Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000601:surgery*; D016896:Treatment Outcome