Bipolar affective disorder associated with beta-thalassemia minor.
A family suggesting cosegregation of beta-thalassemia minor and bipolar affective disorder was reported. The monogenic hereditary anemia was surveyed over three generations in this family, and three patients with the beta-thalassemia and the bipolar affective disorder were observed over two generations. The localization of a gene responsible for bipolar affective disorder was discussed on the basis of previous reports.
Harada
H
H
Department of Neuropsychiatry, Kyoto Prefectural University of Medicine, Japan.
Nakajima
T
T
Inazawa
J
J
Abe
T
T
D001714:Bipolar Disorder / Q000235:genetics*; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D004827:Epilepsy / Q000235:genetics; D005260:Female; D008040:Genetic Linkage / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D010552:Personality Assessment; D017086:beta-Thalassemia / Q000235:genetics*