Polymyositis associated with Ki-1 lymphoma.
We report here a case of acute polymyositis associated with a Ki-1 non-Hodgkin's lymphoma (NHL). This anaplastic large cell malignant lymphoma was a primary T-cell NHL lymphoma of the bone marrow. The malignant cells expressed the CD30 (Ki-1), CD3, and CD4 antigens, the beta chain of the interleukin 2 receptor (CD25), and the betaF1 antigen (alpha/beta T-cell receptor). Chemotherapy and high dose methylprednisolone pulse therapy were initiated. However, no clinical improvement was noticed, because the patient rapidly died of an acute respiratory distress syndrome. To our best knowledge, this represents the first case of Ki-1 lymphoma associated with Polymyositis.
Bouscary
D
D
Department of Hematology Internal Medicine, Hospital Cochin, Paris, France.
Tulliez
M
M
Dreyfus
F
F
Raphael
M
M
Hermine
O
O
Picard
F
F
Delsol
G
G
Sicard
D
D
D000208:Acute Disease; D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D016130:Immunophenotyping; D017728:Lymphoma, Large-Cell, Anaplastic / Q000150:complications* / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000150:complications* / Q000473:pathology; D008297:Male; D017285:Polymyositis / Q000150:complications* / Q000473:pathology