[Role of immunological factors in peripheral vitreo-chorioretinal dystrophies and macular ruptures of the retina].
The authors analyze the results of clinical and immunological examinations of patients with peripheral vitreo-chorioretinal dystrophies (PVCRD) and macular ruptures of the retina. No antibodies to S-AG were detected in the lacrimal fluid in 87.5% of patients with PVCRD without retinal defects. In patients with PVCRD with retinal defects antibodies to S-AG were detected in 70% of cases. These antibodies were absent in the patients with macular ruptures of the retina. In none of the patients were these antibodies detected in the blood serum. The levels of circulating immune complexes were normal in the patients PVCRD and increased in those with macular ruptures of the retina. These data permit a hypothesis on the development of local autoimmune reactions in PVCRD patients in response to the appearance of AG of the injured tissues.
Balashova
L M
LM
Saksonova
E O
EO
Zaĭtseva
N S
NS
Slepova
O S
OS
Teplinskaia
L E
LE
Il'nitskiĭ
V V
VV
Grishin
V L
VL
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D015862:Choroid Diseases / Q000276:immunology; D005128:Eye Diseases / Q000276:immunology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D012162:Retinal Degeneration / Q000276:immunology*; D012167:Retinal Perforations / Q000276:immunology*; D013666:Tears / Q000276:immunology; D014822:Vitreous Body
D000936:Antigen-Antibody Complex
Izuchenie roli immunologicheskikh faktorov pri perifericheskikh vitreokhorioretinal'nykh distrofiiakh i makuliarnykh razryvakh setchatki.