title: [Hyperuricemia and cardiac risK factors: epidemiologic study in the aged].
abstract: The aim of our study is to evaluate whether hyperuricemia may be considered a cardiovascular risk factor also in the elderly. 370 subjects over 60-years-old of both sexes were examined of which 148 presented an ischemic heart disease and 222, age and sex homogeneous, were considered as control group. Serum uric acid was determined. A strong difference among the two groups (p < 0.001) was statistically demonstrated. Such modifications were sex independent. A strict correlation of hyperuricemia and hyper trygliceridemia was present; in fact high uric acid levels were mostly found in the group with triglycerides > 200 mg/dl (p < 0.02). In the whole group and in males a stability of uric acid was noted. In females a significant increase among the first (60-69 years) and the second (70-79 years) age class was present. In conclusion, a positive role of hyperuricemia in the ischemic heart disease pathogenesis is possible.
authors.affiliation: Divisione di Medicina Geriatrica, INRCA, Ancona.
authors.forename: G
authors.initials: G
authors.lastname: Cadeddu
authors.forename: P
authors.initials: P
authors.lastname: Fioravanti
authors.forename: R
authors.initials: R
authors.lastname: Antonicelli
authors.forename: P M
authors.initials: PM
authors.lastname: Gasparrini
authors.forename: R
authors.initials: R
authors.lastname: Gaetti
mesh_terms: D000367:Age Factors; D000368:Aged; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood*
chemical_list: D014280:Triglycerides; D014527:Uric Acid
vernacular_title: Iperuricemia e rischio cardiovascolare: studio epidemiologico nell'anziano.