title: [Bilateral breast carcinoma after recurrent myxoid liposarcoma of the breast].
abstract: The case is presented of a 26-year-old woman with myxoid liposarcoma of the right breast who developed a relapse with anaplastic spindle-cell mesenchymal tumor 7 months after primary therapy. Additionally, 13 months later a bilateral adeno-carcinoma of differing histological grade occurred in the breasts. To the best of our knowledge, no comparable sarcoma-carcinoma sequence in the mammary gland has been reported. For this reason this case is discussed, with special emphasis on possible causative factors and the relationship to the Li-Fraumeni syndrome.
authors.affiliation: Institut für Pathologie, Universität zu Köln.
authors.forename: B R
authors.initials: BR
authors.lastname: Titius
authors.forename: U J
authors.initials: UJ
authors.lastname: Göhring
authors.forename: A
authors.initials: A
authors.lastname: Scharl
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005260:Female; D006801:Humans; D016864:Li-Fraumeni Syndrome / Q000473:pathology / Q000601:surgery; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D015409:Mastectomy, Radical; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D012086:Reoperation; D012509:Sarcoma / Q000473:pathology* / Q000601:surgery
vernacular_title: Bilaterales Mammakarzinom nach rezidivierendem myxoiden Liposarkom der Mamma.