Preliminary microwave irradiation of water solutions changes their channel-modifying activity.
Earlier we have shown that millimetre microwaves (42.25 GHz) of non-thermal power, upon direct admittance into an experiment bath, greatly influence activation characteristics of single Ca(2+)-dependent K+ channels (in particular, the channel open state probability, Po). Here we present new data showing that similar changes in Po arise due to the substitution of a control bath solution for a preliminary microwave irradiated one of the same composition (100 mmol/l KCl with Ca2+ added), with irradiation time being 20-30 min. Therefore, due to the exposure to the field the solution acquires some new properties that are important for the channel activity. The irradiation terminated, the solution retains a new state for at least 10-20 min (solution memory). The data suggest that the effects of the field on the channels are mediated, at least partially, by changes in the solution properties.
Fesenko
E E
EE
Laboratory of Reception Biophysics, Institute of Cell Biophysics of Russian Academy of Sciences, Pushchino, Moscow Region.
Geletyuk
V I
VI
Kazachenko
V N
VN
Chemeris
N K
NK
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002522:Chlorocebus aethiops; D004574:Electromagnetic Fields; D007700:Kinetics; D008872:Microwaves; D015221:Potassium Channels / Q000378:metabolism / Q000528:radiation effects*; D012996:Solutions; D014709:Vero Cells; D014867:Water / Q000737:chemistry*
D015221:Potassium Channels; D012996:Solutions; D014867:Water; D002118:Calcium