title: Blood pressure as a risk factor for depression in elderly people: a prospective study.
abstract: A total of 1070 men and women aged 65 years and over living in the community in Liverpool were interviewed using the Geriatric Mental State. Diagnoses of depression at case and subcase level were made using the GMS-AGECAT package from an initial interview and at follow-up three years later. Data relating to blood pressure at year 0 was available on 748 subjects. Men not taking anti-hypertensives or antidepressants with diastolic blood pressure greater than 85 mmHg were significantly less likely to be subcases than men with low or normal diastolic pressure. People in this group were also significantly less likely to be cases 3 years later. There were no other significant findings. These results do not support an association between low blood pressure and coincidental or future subcase- or case-level depressive illness.
authors.affiliation: University of Liverpool Department of Psychiatry, Royal Liverpool University Hospital, United Kingdom.
authors.forename: C
authors.initials: C
authors.lastname: Gilmore
authors.forename: B H
authors.initials: BH
authors.lastname: Green
authors.forename: J R
authors.initials: JR
authors.lastname: Copeland
authors.forename: M E
authors.initials: ME
authors.lastname: Dewey
authors.forename: I A
authors.initials: IA
authors.lastname: Davidson
authors.forename: P A
authors.initials: PA
authors.lastname: Saunders
authors.forename: V
authors.initials: V
authors.lastname: Sharma
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003866:Depressive Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D007022:Hypotension / Q000150:complications* / Q000453:epidemiology / Q000523:psychology; D008137:Longitudinal Studies; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D006113:United Kingdom / Q000453:epidemiology