title: Pseudoporphyria due to naproxen. A cluster of 3 cases.
abstract: Pseudoporphyria is a photo-induced blistering disorder with increased skin fragility, caused among others by nonsteroidal antiinflammatory drugs. Lesions heal with scarring and milia. Porphyrin screen studies are normal in this disease. Histology and immunofluorescence resembles porphyria cutanea tarda. In this report we describe a cluster of three cases of naproxen-induced pseudoporphyria, and review briefly previously reported cases induced by naproxen. The majority of reported cases involve children. Physicians should be aware of this reversible skin disorder.
authors.affiliation: Dept rheumatology, University Hospital Nijmegen, The Netherlands.
authors.forename: M C
authors.initials: MC
authors.lastname: Creemers
authors.forename: A
authors.initials: A
authors.lastname: Chang
authors.forename: M J
authors.initials: MJ
authors.lastname: Franssen
authors.forename: T J
authors.initials: TJ
authors.lastname: Fiselier
authors.forename: P L
authors.initials: PL
authors.lastname: van Riel
mesh_terms: D000328:Adult; D001168:Arthritis / Q000188:drug therapy; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009288:Naproxen / Q000009:adverse effects*; D011164:Porphyrias / Q000139:chemically induced*
chemical_list: D009288:Naproxen