title: [Richter syndrome: morphologic transformation with persistence of the same phenotype].
abstract: Richter's syndrome is termed as the occurrence of a high-grade lymphoma along with a chronic lymphocytic leukaemia. We report a patient diagnosed as having a CLL evolving into an immunoblastic lymphoma. In spite of this morphologic change, the same identical immunophenotype remained in both types of cells assessed, that is, CLL-type lymphocytes and immunoblastic and lymphoplasmocytoid cells. This event appears to favour the common clonal origin of these two entities.
authors.affiliation: Servicio de Hematología y Hemoterapia, Hospital Universitario Virgen del Rocío, Sevilla.
authors.forename: A
authors.initials: A
authors.lastname: Medina Pérez
authors.forename: E
authors.initials: E
authors.lastname: Ríos Herranz
authors.forename: A
authors.initials: A
authors.lastname: Martín Noya
authors.forename: J
authors.initials: J
authors.lastname: Prieto Fernández
authors.forename: C
authors.initials: C
authors.lastname: Bodineau
authors.forename: J
authors.initials: J
authors.lastname: de Blas
authors.forename: J M
authors.initials: JM
authors.lastname: Rodríguez Fernández
mesh_terms: D000368:Aged; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000276:immunology / Q000473:pathology; D008297:Male; D013577:Syndrome
vernacular_title: Síndrome de Richter: transformación morfológica con persistencia del mismo fenotipo.