title: Acute neutrophilic myositis in Sweet's syndrome: late phase transformation into fibrosing myositis and panniculitis.
abstract: Early in the course of myeloblastic leukemia a patient concurrently developed febrile neutrophilic dermatosis and sterile acute myositis. The dermatitis and myositis were unresponsive to antibiotic therapy but remitted within a few days of institution of steroid treatment. The patient died of myocardial infarction. At autopsy the dermis was normal. Previously effected muscles were scarred. The overlying fascia and subcutaneous septa were fibrotically thickened. In addition, segmental acute aortitis was detected. Acute myositis and aortitis may reflect further organ manifestations of the Sweet's reactivity pattern. It is proposed that Sweet's myositis and dermatitis may evolve into a fibrosing myositis and panniculitis.
authors.affiliation: Department of Haematology, Bnai-Zion Medical Center, Haifa, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Attias
authors.forename: R
authors.initials: R
authors.lastname: Laor
authors.forename: E
authors.initials: E
authors.lastname: Zuckermann
authors.forename: J E
authors.initials: JE
authors.lastname: Naschitz
authors.forename: M
authors.initials: M
authors.lastname: Luria
authors.forename: I
authors.initials: I
authors.lastname: Misselevitch
authors.forename: J H
authors.initials: JH
authors.lastname: Boss
mesh_terms: D000208:Acute Disease; D005260:Female; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008875:Middle Aged; D009220:Myositis / Q000209:etiology / Q000473:pathology*; D015434:Panniculitis / Q000473:pathology; D016463:Sweet Syndrome / Q000209:etiology / Q000473:pathology*