title: [Nootropic substances enhance the N-methyl-D-aspartate-induced short-term potentiation of synaptic transmission in rat hippocampal slices].
abstract: The nootropic agents pyracetam, ethymisole, N-5-oxynicotinoyl glutamate and beta-carboline derivative--ambocarb--enhance short-term potentiation of populational EPSP's amplitude of area CA1 pyramidal neurons in the slices of the rat hippocampus, which is evoked by NMDA. The inhibitors of protein kinases diminish the effect of pyracetam and ethymisole (tolbutamide), as well as all the studied nootropic drugs (polymyxin B and trifluoroperazine).
authors.forename: I I
authors.initials: II
authors.lastname: Abramets
authors.forename: P V
authors.initials: PV
authors.lastname: Andreev
authors.forename: I M
authors.initials: IM
authors.lastname: Samoĭlovich
mesh_terms: D000818:Animals; D004357:Drug Synergism; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D006624:Hippocampus / Q000187:drug effects* / Q000502:physiology; D066298:In Vitro Techniques; D016202:N-Methylaspartate / Q000494:pharmacology*; D018697:Nootropic Agents / Q000494:pharmacology*; D017966:Pyramidal Cells / Q000187:drug effects / Q000502:physiology; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors
chemical_list: D018697:Nootropic Agents; D016194:Receptors, N-Methyl-D-Aspartate; D016202:N-Methylaspartate
vernacular_title: Nootropnye veshchestva usilivaiut vyzyvaemuiu N-metil-D-aspartatom kratkosrochnuiu potentsiatsiiu sinapticheskoĭ peredachi v srezakh gippokampa krys.