title: [Follow-up study of pulmonary function in individuals subjected to lobectomy in infancy and childhood].
abstract: Experimental research in animals have demonstrated that pulmonary development continues after birth. This happens in man as well: alveolar proliferation and enlargement go on until the eighth year of age, furthermore complete pulmonary development is achieved until the 20-22 years of age. It is therefore possible to hypothesise that respiratory deficit following pulmonary exeresis in children would regress with time. In the Pediatric Surgery of IRCCS Policlinico S. Matteo of Pavia eight children, 4 days to 8 years of age, underwent lobectomy for pulmonary hypertensive emphysema (3), lung abscess (2), bronchogenic cysts (2) and hystiocytoma (1). One of them was lost to follow-up; the remainders were controlled from 3 to 25 years after surgery: all of them enjoy a normal active life. Respiratory function was evaluated through blood chemistry, blood gas analysis, basal and after strain ECG, chest X-ray, spirometry, basal and after strain pulmonary scintigraphy. Basal and after strain ECG, chest X-ray, and arterial blood gas were normal in every examined subjects; spirometry, although results are quite variable, did not show serious respiratory deficits; basal after strain pulmonary scintigraphies weren't homogeneous. These results, although they aren't univocally interpretable, positively confirmed that the residual lung after lobectomy has a satisfactory possibility of functional recovery.
authors.affiliation: Università degli Studi, IRCCS Policlinico S. Matteo, Pavia.
authors.forename: G
authors.initials: G
authors.lastname: Verga
authors.forename: S
authors.initials: S
authors.lastname: Minniti
authors.forename: P
authors.initials: P
authors.lastname: Donati
authors.forename: P
authors.initials: P
authors.lastname: Spina
authors.forename: L
authors.initials: L
authors.lastname: Verga
mesh_terms: D001784:Blood Gas Analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D011656:Pulmonary Emphysema / Q000503:physiopathology* / Q000601:surgery*; D011877:Radionuclide Imaging; D012129:Respiratory Function Tests; D013147:Spirometry; D016896:Treatment Outcome
vernacular_title: Valutazione a distanza della funzionalità respiratoria in individui sottoposti a lobectomia polmonare in età pediatrica.