Development of the zebrafish nervous system: genetic analysis and manipulation.
The accessibility and simplicity of the zebrafish embryo have led to fruitful examinations of how vertebrate embryos develop, at the cellular level. Recently, several groups have initiated large-scale mutagenesis in zebrafish and begun to generate transgenic zebrafish. The goals of these endeavors are to identify developmentally important genes and to delineate their in vivo function. If successful, the two approaches should significantly enhance our understanding of how genes control development in a vertebrate embryo.
Kuwada
J Y
JY
Department of Biology, University of Michigan, Ann Arbor 48109-1048, USA.
D000818:Animals; D005796:Genes; D009154:Mutation / Q000235:genetics*; D009420:Nervous System / Q000196:embryology*; D018377:Neurotransmitter Agents / Q000235:genetics*; D010641:Phenotype; D015027:Zebrafish / Q000196:embryology*
D018377:Neurotransmitter Agents