[The isolation of the Vibrio cholerae dermotoxin and the characterization of its biological properties].
The dermonecrotic factor (dermotoxin) inducing skin necrosis in rabbits has been isolated from V. cholerae strain B-53-2-38 and partially purified. Dermotoxin has a molecular weight of about 110 kD and possesses pronounced cytotoxic and general toxic action, differing from that of enterotoxin. The introduction of this factor into the blood and peritoneum of laboratory animals causes their death.
Atarova
G T
GT
Pomukhina
O I
OI
Mishan'kin
B N
BN
Uraleva
V S
VS
Cherepakhina
I Ia
IIa
Sal'nikova
O I
OI
Kozyreva
L A
LA
Gorina
O M
OM
D000818:Animals; D000833:Animals, Suckling; D001431:Bacteriological Techniques; D002772:Cholera Toxin / Q000302:isolation & purification* / Q000633:toxicity; D003885:Dermotoxins / Q000302:isolation & purification* / Q000633:toxicity; D006168:Guinea Pigs; D051379:Mice; D008970:Molecular Weight; D011817:Rabbits; D012867:Skin / Q000187:drug effects; D014734:Vibrio cholerae / Q000472:pathogenicity*
D003885:Dermotoxins; D002772:Cholera Toxin
Vydelenie dermotoksina Vibrio cholerae i kharakteristika ego biologicheskikh svoĭstv.