Tissue- and development-specific expression of goat insulin-like growth factor-I (IGF-I) mRNAs.
We cloned four kinds of goat insulin-like growth factor-I (IGF-I) cDNAs. Each of them encodes the same mature IGF-I and different signal peptides. In this study, we analyzed expression of the four kinds of mRNAs in tissues in various developmental stages by a reverse transcriptase-polymerase chain reaction assay. The results suggest that their expression may be controlled by different promoters, the activities of which are tissue- and development-specific.
Mikawa
S
S
Department of Agricultural Chemistry, Kyoto University, Japan.
Yoshikawa
G
G
Yamano
Y
Y
Sakai
H
H
Komano
T
T
Hosoi
Y
Y
Utsumi
K
K
D000818:Animals; D001483:Base Sequence; D017931:DNA Primers; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006041:Goats; D007334:Insulin-Like Growth Factor I / Q000235:genetics*; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000235:genetics*
D017931:DNA Primers; D012333:RNA, Messenger; D007334:Insulin-Like Growth Factor I