Cutaneous Rosai-Dorfman disease presenting as a suspicious breast mass.
Cutaneous Rosai-Dorfman disease in a male patient presented as a clinically malignant left breast mass. The intra-operative frozen section indicated a benign inflammatory lesion and a simple excision was performed. The disease was apparently limited to the skin and subcutis of the left breast with no lymph nodes or other organs involvement. While the lesion demonstrated the characteristic morphology of Rosai-Dorfman disease, the diagnosis of granulomatous mastitis, epithelioid sarcoma and other cutaneous xanthohistiocytic proliferations were considered. In the absence of lymphadenopathy, a high index of diagnostic awareness is required to recognize the uncommon, solitary cutaneous Rosai-Dorfman disease.
Mac-Moune Lai
F
F
Department of Anatomical & Cellular Pathology, Chinese University of Hong Kong, Shatir.
Lam
W Y
WY
Chin
C W
CW
Ng
W L
WL
D000328:Adult; D001940:Breast / Q000473:pathology; D018567:Breast Neoplasms, Male / Q000473:pathology*; D003937:Diagnosis, Differential; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male