title: Hepatocyte proliferation in silicotic rat liver after partial hepatectomy.
abstract: Liver silicosis was induced in rats by an intravenous injection of silica particles. The presence of silicotic granulomas in the liver lowered the initial response of hepatocytes to partial (37%) hepatectomy and slowed down the decline in the number of dividing cells 6 days after the stimulus, but did not affect significantly the total number of mitotic cells.
authors.affiliation: Department of Physiology, Faculty of Medicine, Charles University, Hradec Králové, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Kanta
mesh_terms: D000818:Animals; D002455:Cell Division; D004247:DNA / Q000096:biosynthesis; D005260:Female; D006498:Hepatectomy; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D008115:Liver Regeneration / Q000502:physiology; D008938:Mitosis / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D012829:Silicosis / Q000378:metabolism / Q000473:pathology*; D013936:Thymidine / Q000378:metabolism
chemical_list: D004247:DNA; D013936:Thymidine