A bioimaging integration system implemented for neurological applications.
A system aimed at the management and fusion of multimodal biomedical images, including X-ray computed tomography, magnetic resonance imaging, positron emission tomography, and single photon emission computed tomography, has been implemented for neurological applications. This bioimaging integration system (BIS) consists of a network for image transmission from acquisition machines to dedicated image processing workstations, a software library for image standardization, and an image registration technique to project multimodal volumetric images into a common reference space. The registration procedure was evaluated in MRI/PET correlation studies, in which misalignment errors of 2.6 mm in the xy transaxial plane and 3.4 mm along the z axis were found. BIS has been validated for the anatomical-functional correlation analysis of MRI and PET images in neurological research protocols and clinical studies.
Rizzo
G
G
INB-CNR, University of Milan, Italy.
Gilardi
M C
MC
Prinster
A
A
Lucignani
G
G
Bettinardi
V
V
Triulzi
F
F
Cardaioli
A
A
Cerutti
S
S
Fazio
F
F
D001927:Brain Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003195:Computer Communication Networks; D003952:Diagnostic Imaging; D006801:Humans; D007256:Information Systems; D008279:Magnetic Resonance Imaging; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed