[Phenomenon of tumor growth stability in the host's body. New approach to growth and treatment of tumors].
The impact of surgical treatment of Ehrlich's carcinoma on animals' survival was studied. Tumour removal on posttransplantation day 30 was shown to cause no increases in the longevity of the animals operated on as compared with those non-operated on (mean longevity was 59.9 and 62.2 days, respectively). The death causes of the animals operated on were metastases and relapses. On day 7 after transplantation, cyclophosphanum therapy of Ehrlich's carcinoma failed to prolong the animals' life. While 24 hours after tumour transplantation the longevity increased from 61.8 to 93.4 days. No therapeutical effects were shown to be associated with the influence of humoral factors of the host body on tumor growth. It was shown that the lack of these humoral factors resulted in interrupting tumor growth.
Donenko
F V
FV
Moroz
L V
LV
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D003520:Cyclophosphamide / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D012008:Recurrence; D013997:Time Factors
D003520:Cyclophosphamide
Fenomen stabili'nosti rosta opukholi v organizme khoziaina. Novyĭ podkhod v kontsentratsii rosta i lecheniia opukholi.