[Effect of natural complexes of biologically active substances on liver regeneration in alcohol poisoning].
Hepatoprotective effect of natural substances obtained from extracts of grape combs, leaves of green and black tea were studied in liver tissue of ethanol-consuming rats by means of evaluation of the neutral lipid fractions and phospholipids as well as by measurement of glucose and nicotinamide coenzymes NAD+ and NADP in blood. In all the animal groups treated with these vegetable extracts content of total phospholipids, decreased after the ethanol treatment, was increased, while fraction composition of phospholipids and of neutral lipids was normalized; in blood content of glucose, NAD+ and NADP approached to control values. These results suggest that the vegetable extracts studied exhibited the hepatoprotective effect in alcohol intoxication.
Kushnerova
N F
NF
Fomenko
S E
SE
Polozhentseva
M I
MI
Bulanov
A E
AE
D000428:Alcohol Drinking / Q000009:adverse effects* / Q000503:physiopathology; D000818:Animals; D005638:Fruit / Q000737:chemistry; D008055:Lipids / Q000097:blood; D008099:Liver / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D018515:Plant Leaves / Q000737:chemistry; D051381:Rats; D013662:Tea / Q000737:chemistry
D008055:Lipids; D010936:Plant Extracts; D013662:Tea; D009243:NAD; D009249:NADP
Vliianie prirodnykh kompleksov biologicheski aktivnykh veshchestv na protsessy vosstanovleniia funktsiĭ pecheni pri alkogol'noĭ intoksikatsii.