title: Epilepsy and associated effects on adaptive behaviour in adults with Down syndrome.
abstract: A total of 201 adults with Down syndrome were investigated, of whom 32 (15.9%) had epilepsy. A bimodal age distribution for seizure onset in childhood and later in middle-age was found. Good seizure control was associated with early onset epilepsy. Down syndrome adults with epilepsy scored significantly higher overall on the adaptive behaviour profile but did not have significantly greater maladaptive behaviours.
authors.affiliation: Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Edgbaston, UK.
authors.forename: V P
authors.initials: VP
authors.lastname: Prasher
mesh_terms: D000203:Activities of Daily Living / Q000145:classification*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002540:Cerebral Cortex / Q000503:physiopathology; D015331:Cohort Studies; D004314:Down Syndrome / Q000503:physiopathology* / Q000534:rehabilitation; D004569:Electroencephalography; D004739:England; D004827:Epilepsy / Q000503:physiopathology* / Q000534:rehabilitation; D005260:Female; D006801:Humans; D007859:Learning Disabilities / Q000503:physiopathology / Q000534:rehabilitation; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged