title: [Protective properties of M. lufu in experimental leprosy].
abstract: A protective potential of M. lufu against experimental lepra was studied in mice infected with M. leprae according to Shepard. 5 and 9 months after the inoculation quantitation of the causative agent in the animals' paws indicated a protective action of M. lufu which exceeded that of BCG, M. vaccae and M. leprae. High protective activity of M. lufu is due both to its antigenic composition similarity with M. leprae and influence on immune response regulation. It is suggested to use M. lufu for design of highly effective antilepra vaccine.
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Iushin
authors.forename: O V
authors.initials: OV
authors.lastname: Kalianina
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis / Q000276:immunology; D001500:BCG Vaccine / Q000276:immunology; D001428:Bacterial Vaccines / Q000276:immunology; D007918:Leprosy / Q000276:immunology* / Q000517:prevention & control; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009161:Mycobacterium / Q000276:immunology*; D009166:Mycobacterium leprae / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D001500:BCG Vaccine; D001428:Bacterial Vaccines
vernacular_title: Protektivnye svoĭstva M. lufu pri éksperimental'noĭ leproznoĭ infektsii.