title: [Neuroimmune interactions in the gastrointestinal tract].
abstract: The enteric nervous system and immune system are integrated systems that play an important role in the regulation of gastrointestinal functions. Recent studies suggest a bidirectional interaction between both systems. The relationship is based on the synthesis and release of neuropeptides from immune cells and the receptor-mediated alteration of nervous and immune functions by neurotransmitters and inflammatory mediators. The activity of the enteric nervous and immune system can be modulated by the central nervous system. These psycho-neuro-immuno-interactions are involved in gut inflammation, in functional bowel diseases and in the physiological control of gastrointestinal functions.
authors.affiliation: Abteilung für Gastroenterologie, Heinrich-Heine-Universität Düsseldorf.
authors.forename: T
authors.initials: T
authors.lastname: Frieling
authors.forename: G
authors.initials: G
authors.lastname: Strohmeyer
mesh_terms: D000818:Animals; D003109:Colonic Diseases, Functional / Q000276:immunology; D017615:Enteric Nervous System / Q000503:physiopathology*; D005759:Gastroenteritis / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D018836:Inflammation Mediators / Q000378:metabolism*; D018377:Neurotransmitter Agents / Q000502:physiology*; D011598:Psychoneuroimmunology
chemical_list: D018836:Inflammation Mediators; D018377:Neurotransmitter Agents
vernacular_title: Neuroimmune Interaktionen im Gastrointestinaltrakt.