[The assessment of left ventricular diastolic function in patients with systemic scleroderma by radionuclide ventriculography].
To assess left ventricular (LV) diastolic function in scleroderma systematica (SS) with regard to SS course and skin lesion degree, a total of 24 SS patients were examined versus control subjects. Though cardiac symptoms manifested clinically only in 8 patients, parameters of LV diastolic function underwent changes in the majority of the examinees: the time to attaining maximal filling velocity increased, contribution of the first diastolic third to LV filling diminished, hemodynamic significance of the left atrial systole grew. More pronounced dysfunction of the myocardium occurred in patients with diffuse skin lesions, acute and subacute disease who also appeared to have reduced LV ejection fraction. The conclusion is made on frequent subclinical pattern of myocardial involvement in SS patients which runs primarily as LV diastolic dysfunction. Systolic disturbance emerge later or in more active forms.
Bogdanov
A P
AP
Malov
A G
AG
Moiseev
S V
SV
Guseva
N G
NG
D000208:Acute Disease; D000328:Adult; D002908:Chronic Disease; D003971:Diastole; D005260:Female; D015637:Gated Blood-Pool Imaging / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D013670:Sodium Pertechnetate Tc 99m; D016277:Ventricular Function, Left
D013670:Sodium Pertechnetate Tc 99m
Otsenka diastolicheskoĭ funktsii levogo zheludochka serdtsa u bol'nykh sistemnoĭ sklerodermieĭ metodom radionuklidnoĭ ventrikulografii.