title: Simultaneous aortic and renal artery reconstruction: evolution of an eighteen-year experience.
abstract: OBJECTIVE
  We reviewed an 18-year experience with combined abdominal aortic and renal artery reconstruction (AOR) with a particular focus on patients' clinical risk profile and surgical results in contemporary practice as compared with earlier experience.
  
  
  METHODS
  One hundred seventy patients underwent AOR during the interval January 1, 1976 to June 30, 1994. To examine parameters representative of current practice, the cohort was divided into group I patients (n = 110) treated before 1990 and group II (n = 60) treated between 1990 and 1994. Median follow-up duration for the entire cohort was 8.4 +/- 0.6 years. Renal artery reconstruction patency and patient survival rates were calculated by life-table methods. Logistic and Cox regression analysis were used to determine predictors of perioperative and long-term morbidity/mortality rates.
  
  
  RESULTS
  Although demographic features changed little over the review period, the detection (56% vs 73%, p = 0.03) and treatment with percutaneous transluminal coronary angioplasty/coronary artery bypass grafting (11% vs 40%, p = 0.0001) of associated coronary artery disease were more frequent in group I patients. The operative mortality rate for the entire cohort was 6.5% (group I = 9% vs group II = 2%, p = 0.06). Changing trends of surgical techniques over the review period included (group I vs II, respectively) increased use of bilateral simultaneous renal artery repair (12% vs 25%, p < 0.005) and transaortic endarterectomy as the renal artery reconstruction technique (3% vs 25%, p < 0.0001). Favorable response in blood pressure control was noted in 68% of group II patients. The cumulative 5-year survival rate for all patients was 75% with an initial serum creatinine of 2.0 mg/dl or greater being the only negative predictor of late survival after regression analysis.
  
  
  CONCLUSIONS
  The current operative mortality rate for AOR is in the range anticipated for aortic surgery alone, and this appears to be related to improved detection and treatment of associated coronary artery disease and intervention before major deterioration in renal function. These findings coupled with currently available natural history data relative to renovascular disease justify an aggressive approach with AOR when significant renal artery stenosis is detected during evaluation of aortic disease.
authors.affiliation: Division of Vascular Surgery, Massachusetts General Hospital, Boston 02114, USA.
authors.forename: R P
authors.initials: RP
authors.lastname: Cambria
authors.forename: D C
authors.initials: DC
authors.lastname: Brewster
authors.forename: G
authors.initials: G
authors.lastname: L'Italien
authors.forename: G
authors.initials: G
authors.lastname: Koustas
authors.forename: S
authors.initials: S
authors.lastname: Atamian
authors.forename: G M
authors.initials: GM
authors.lastname: LaMuraglia
authors.forename: J P
authors.initials: JP
authors.lastname: Gertler
authors.forename: W M
authors.initials: WM
authors.lastname: Abbott
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000601:surgery*; D001018:Aortic Diseases / Q000150:complications / Q000401:mortality / Q000601:surgery; D001161:Arteriosclerosis / Q000401:mortality / Q000601:surgery; D001807:Blood Vessel Prosthesis; D015331:Cohort Studies; D003327:Coronary Disease / Q000150:complications / Q000628:therapy; D004691:Endarterectomy; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D011183:Postoperative Complications; D012044:Regression Analysis; D012077:Renal Artery / Q000601:surgery*; D012078:Renal Artery Obstruction / Q000150:complications / Q000401:mortality / Q000601:surgery; D015996:Survival Rate