Hemolytic uremic syndrome with particular involvement of basal ganglia and favorable outcome.
Two children with hemolytic uremic syndrome and extrapyramidal complications are presented. Neuroimaging studies demonstrated bilateral basal ganglia (striatal) involvement with favorable recovery in both patients. The pathophysiology of the neurologic complications in hemolytic uremic syndrome are probably multifactorial. Our patients suggest a reversible process because both patients recovered clinically and radiographically. Neurologic complications do not always portend a poor prognosis and, in general, involvement of the basal ganglia is associated with favorable outcome.
Barnett
N D
ND
Division of Pediatrics, Phoenix Children's Hospital, AZ 85006, USA.
Kaplan
A M
AM
Bernes
S M
SM
Cohen
M L
ML
D001479:Basal Ganglia / Q000473:pathology / Q000503:physiopathology; D001480:Basal Ganglia Diseases / Q000175:diagnosis* / Q000503:physiopathology; D002648:Child; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D016896:Treatment Outcome