title: Dioxides of bicyclic thiadiazines: a new family of smooth muscle relaxants.
abstract: The synthesis of dioxides of bicyclic thiadiazine related to diazoxide has been achieved. In a preliminary test, some of these compounds show smooth muscle relaxation similar to that obtained with the reference standard diazoxide.
authors.affiliation: Instituto de Química Médica (C.S.I.C.), Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Castro
authors.forename: A
authors.initials: A
authors.lastname: Martínez
authors.forename: I
authors.initials: I
authors.lastname: Cardelús
authors.forename: J
authors.initials: J
authors.lastname: Llenas
mesh_terms: D000818:Animals; D003981:Diazoxide / Q000494:pharmacology; D006168:Guinea Pigs; D009682:Magnetic Resonance Spectroscopy; D009126:Muscle Relaxation / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects*; D051381:Rats; D013829:Thiadiazines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D013829:Thiadiazines; D003981:Diazoxide