title: Late thalamic atrophy in infarction of the middle cerebral artery territory in neonates. A prospective clinical and radiological study in four children.
abstract: We report four cases of progressive thalamic atrophy following ipsilateral cerebral infarction in the territory of the middle cerebral artery in neonates, with prospective radiological and clinical follow-up. This type of atrophy appears within 6 months after the onset of cerebral infarction. In the short term, this atrophy has no action on sensory and memory function and/or on sensory evoked potentials. This atrophy is not the result of secondary ischemic neuronal damage. Judging from several other experimental studies, thalamic atrophy may primarily result from retrograde degeneration. It would be interesting to observe the consequences of this atrophy on sensory and memory function over a long period.
authors.affiliation: Service de Neurologie, Centre Hospitalo-Universitaire, Dijon, France.
authors.forename: M
authors.initials: M
authors.lastname: Giroud
authors.forename: H
authors.initials: H
authors.lastname: Fayolle
authors.forename: D
authors.initials: D
authors.lastname: Martin
authors.forename: N
authors.initials: N
authors.lastname: Baudoin
authors.forename: N
authors.initials: N
authors.lastname: André
authors.forename: J B
authors.initials: JB
authors.lastname: Gouyon
authors.forename: J L
authors.initials: JL
authors.lastname: Nivelon
authors.forename: R
authors.initials: R
authors.lastname: Dumas
mesh_terms: D002536:Cerebral Arteries / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D011446:Prospective Studies; D013788:Thalamus / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed