Spatial and temporal distribution of 7B2 in the pulmonary diffuse neuroendocrine system of the cat.
The postnatal developmental profile of the presence of 7B2 was studied immunocytochemically in the pulmonary diffuse neuroendocrine system of the cat. Labelling was found in neuroepithelial bodies (NEB) but not in solitary neuroendocrine cells. The identity of NEB was confirmed on adjacent serial sections by the immunostaining for protein gene product 9.5, a pan-neuroendocrine marker. The first 3 weeks after birth 7B2 stained NEB were most abundant with a subsequent decline thereafter. The positive correlation between the variation of 7B2 immunoreactivity and number of NEB suggests an important role for 7B2 in NEB.
Seldeslagh
K A
KA
Catholic University of Louvain, Faculty of Medicine, Laboratory for Histopathology, Belgium.
Lauweryns
J M
JM
D000818:Animals; D000831:Animals, Newborn; D002415:Cats; D007150:Immunohistochemistry; D008168:Lung / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D051859:Neuroendocrine Secretory Protein 7B2; D009490:Neurosecretory Systems / Q000166:cytology / Q000378:metabolism*; D010907:Pituitary Hormones / Q000378:metabolism*; D013869:Thiolester Hydrolases / Q000378:metabolism; D013997:Time Factors; D014018:Tissue Distribution; D043222:Ubiquitin Thiolesterase
D009419:Nerve Tissue Proteins; D051859:Neuroendocrine Secretory Protein 7B2; D010907:Pituitary Hormones; D013869:Thiolester Hydrolases; D043222:Ubiquitin Thiolesterase