title: Supratentorial haemangioblastoma not associated with Von Hippel Lindau complex or polycythaemia: case report and literature review.
abstract: Solitary or multiple supratentorial haemangioblastomas are rare and may be associated with Von Hippel Lindau complex (VHLC), polycythaemia or a family history of VHLC. An extensive review of the literature (1902-1992) has revealed 112 cases. They account for 2-8% of all haemangioblastomas and are commonly intraparenchymatous (86.8%) and infrequently intraventricular (6.6%). However, a meningeal location 5.6%) is extremely rare. Only one case of a solitary leptomeningeal haemangioblastoma has previously been reported and this was associated with a family and personal history of VHLC, cerebellar haemangioblastoma and renal carcinoma. We report a solitary solid left parietal leptomeningeal haemangioblastoma mimicking a meningioma or a secondary deposit on computed tomography in a 72-year-old male. There were no manifestations of or a family history of VHLC or polycythaemia.
authors.affiliation: Department of Surgery Neurology, Morriston Hospital, Swansea, Wales.
authors.forename: R R
authors.initials: RR
authors.lastname: Sharma
authors.forename: I P
authors.initials: IP
authors.lastname: Cast
authors.forename: C
authors.initials: C
authors.lastname: O'Brien
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D018325:Hemangioblastoma / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D008578:Meninges / Q000473:pathology; D011086:Polycythemia / Q000235:genetics; D015173:Supratentorial Neoplasms / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D006623:von Hippel-Lindau Disease / Q000235:genetics