[Expression of proliferating cell nuclear antigen (PCNA) in squamous cell carcinoma of the oral cavity].
Proliferating cell nuclear antigen (PCNA) was identified by immunohistochemistry in 52 cases. PCNA-positive cells had been detected in the basal cells of normal epithelium known to contain proliferating cells. PCNA scores of normal epithelium was 1 as "low", and carcinomas were 3 or 4 as "high". The PCNA scores of high-grade carcinoma was significantly higher than the low-grade carcinoma. The study shows that expression of PCNA correlated with carcinoma grade.
Qiao
B
B
School of Stomatology, Beijing Medical University.
Wu
Q
Q
Wu
D
D
D002294:Carcinoma, Squamous Cell / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D009062:Mouth Neoplasms / Q000276:immunology* / Q000473:pathology; D009367:Neoplasm Staging; D018809:Proliferating Cell Nuclear Antigen / Q000378:metabolism*
D018809:Proliferating Cell Nuclear Antigen