title: Discrimination between panic disorder and generalized anxiety disorder by 35% carbon dioxide challenge.
abstract: OBJECTIVE
  The authors' goal was to determine whether 35% carbon dioxide (CO2) challenge would discriminate between patients with panic disorder and patients with other anxiety disorders.
  
  
  METHODS
  Nine patients with panic disorder and nine with generalized anxiety disorder underwent the 35% CO2 challenge.
  
  
  RESULTS
  Patients with panic disorder experienced a significantly stronger increase in subjective anxiety than patients with generalized anxiety disorder. However, increases in panic symptom scores were high in both groups.
  
  
  CONCLUSIONS
  These results suggest that a large increase in subjective anxiety due to the CO2 challenge is specific for patients with panic disorder but that an increase in panic symptoms is not.
authors.affiliation: Department of Psychiatry and Neuropsychology, State University of Limburg, Maastricht, The Netherlands.
authors.forename: K
authors.initials: K
authors.lastname: Verburg
authors.forename: E
authors.initials: E
authors.lastname: Griez
authors.forename: J
authors.initials: J
authors.lastname: Meijer
authors.forename: H
authors.initials: H
authors.lastname: Pols
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000139:chemically induced / Q000175:diagnosis* / Q000523:psychology; D002245:Carbon Dioxide / Q000494:pharmacology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D016584:Panic Disorder / Q000139:chemically induced / Q000175:diagnosis* / Q000523:psychology; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index
chemical_list: D002245:Carbon Dioxide