title: [Detection of nicotine in eccrine sweat after stimulation of sweat glands during nicotine withdrawal].
abstract: The presence of nicotine in sweat obtained from smokers and one non-smoker exposed to tobacco smoke after 4 h to 8 days of nicotine-free time was investigated. Following stimulation of the eccrine glands, sweat samples were taken every hour for 6 h. The total nicotine concentrations, i.e. the sum of nicotine and its metabolites, were determined by radioimmunoassay. The presence of unchanged nicotine was revealed by gas chromatography/mass spectrometry.
authors.affiliation: Institut für Rechtsmedizin, Universität, Ulm.
authors.forename: S
authors.initials: S
authors.lastname: Balabanova
authors.forename: M
authors.initials: M
authors.lastname: Krupienski
mesh_terms: D000293:Adolescent; D000328:Adult; D003367:Cotinine / Q000493:pharmacokinetics; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate / Q000502:physiology; D008875:Middle Aged; D009538:Nicotine / Q000009:adverse effects* / Q000493:pharmacokinetics*; D010862:Pilocarpine; D016540:Smoking Cessation; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000378:metabolism*; D014028:Tobacco Smoke Pollution
chemical_list: D014028:Tobacco Smoke Pollution; D010862:Pilocarpine; D009538:Nicotine; D003367:Cotinine
vernacular_title: Untersuchungen zum Nachweis von Nikotin im ekkrinen Schweiss nach Stimulation der Schweissdrüsen während einer Nikotinkarenz.