title: Histoplasma capsulatum infection in three AIDS patients living in Africa.
abstract: Three AIDS patients are reported, 2 European and 1 African. All 3 developed Histoplasma capsulatum infection while living in Africa. Two developed a pulmonary infiltrate, and 2 had skin lesions. One patient was successfully treated with itraconazole, 400 mg daily; in a second patient, itraconazole was partially successful; the third patient was lost to follow-up before adequate treatment could be started. Histoplasma infection is probably an often undiagnosed complication in African AIDS patients.
authors.affiliation: Institute of Tropical Medicine, Edegem, Antwerp, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Colebunders
authors.forename: K
authors.initials: K
authors.lastname: van den Abbeele
authors.forename: E
authors.initials: E
authors.lastname: Hauben
authors.forename: T
authors.initials: T
authors.lastname: Verstraeten
authors.forename: T
authors.initials: T
authors.lastname: Heremans
authors.forename: J
authors.initials: J
authors.lastname: van den Ende
authors.forename: E
authors.initials: E
authors.lastname: van Marck
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology* / Q000473:pathology; D000328:Adult; D000349:Africa; D003881:Dermatomycoses / Q000150:complications* / Q000473:pathology; D006660:Histoplasmosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000473:pathology; D008297:Male
chemical_list: D017964:Itraconazole