[Tuberculous lymphadenitis: a sarcoidosis-like variation].
By means of polymerase chain reaction technique to amplify DNA sequence specific for mycobacterium tuberculosis (M. TB-PCR), BCG immunohistochemistry (BCG-IHC) as well as acid fast stain (AF), mycobacterium other than tuberculosis (MOTT) and mycobacterium tuberculosis (M. TB) were detected in paraffin blocks from 12 cases diagnosed by consultant pathologists as lymph node "sarcoidosis". Of the 5 cases which consulting pathologists unanimously agreed to the lymph node "sarcoidosis" diagnosis, 1 case showed BCG-IHC (+) and M. TB-PCR (+); Of the 7 cases which most of the consulting pathologists agreed to be "sarcoidosis", 1 case showed AF (+), BCG-IHC (+) and M. TB-PCR (+). The results suggest: (1) some tuberculous lymphadenitis cases may present as "sarcoidosis"-like lesions; (2) lymph node sarcoidosis may be related to MOTT and M. TB infection.
Ding
S
S
Department of Pathology, Tianjin Medical University.
Zhang
N
N
Bu
H
H
D000328:Adult; D004269:DNA, Bacterial / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D012507:Sarcoidosis / Q000382:microbiology* / Q000473:pathology; D014388:Tuberculosis, Lymph Node / Q000382:microbiology* / Q000473:pathology
D004269:DNA, Bacterial