[Individual arterial pressure variability in newborn infants, adults, and the elderly].
The complexity of the cardiovascular function is related to a wide interindividual variability (VA) that changes with age. The aim of our study was to investigate the spontaneous blood pressure (BP) VA in 3 groups of 20 healthy subjects (S) each, 10 M and 10 F: Group I newborns 24 hours old; Group II 30-40 yrs; Group III 70-80 yrs. Each S underwent BP monitoring in a comfortable condition for 15'. Our data show an increase, with age, of both the average systolic and diastolic BP, paralleled by a simultaneous decrease of their standard deviations. Furthermore, the three distributions show a reasonably gaussian behaviour (maximum absolute value of the skewness was 0.21). These results emphasize the age-dependent reduction in functional flexibility of the cardiovascular system. A major pool of subjects is required to confirm our preliminary data.
Colosimo
A
A
Facoltà di Medicina e Chirurgia, Cattedra di Medicina Interna, Università degli Studi di Roma, La Sapienza.
Guarini
G
G
Menghetti
E
E
Tedeschi
D
D
Tilia
P
P
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D012016:Reference Values
Osservazioni sulla variabilità individuale della pressione arteriosa in neonati, adulti e anziani.