title: Antitumor and cardiotonic activity of imidazo[2,1-b]thiazole guanylhydrazones.
abstract: A number of imidazo[2,1-b]thiazole guanylhydrazones, whose antitumor activity has already been described, were tested as potential cardiotonic agents. The guanylhydrazone of 2,3-dihydro-6-chloroimidazo[2,1-b]thiazole-5-carboxaldehyde (2a) was the most interesting compound showing both antitumor and cardiotonic activity.
authors.affiliation: Dipartimento di Scienze Farmaceutiche dell'Universita, Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Andreani
authors.forename: M
authors.initials: M
authors.lastname: Rambaldi
authors.forename: A
authors.initials: A
authors.lastname: Locatelli
authors.forename: R
authors.initials: R
authors.lastname: Bossa
authors.forename: I
authors.initials: I
authors.lastname: Galatulas
authors.forename: G
authors.initials: G
authors.lastname: Salvatore
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002316:Cardiotonic Agents / Q000494:pharmacology*; D006168:Guinea Pigs; D006835:Hydrazones / Q000494:pharmacology; D007093:Imidazoles / Q000494:pharmacology; D066298:In Vitro Techniques; D015394:Molecular Structure
chemical_list: D000970:Antineoplastic Agents; D002316:Cardiotonic Agents; D006835:Hydrazones; D007093:Imidazoles