title: [Lung function in chronic persistent pulmonary embolism].
abstract: Chronic thromboembolic pulmonary hypertension is characterized by widespread obstruction of the pulmonary arteries with organized thrombus. Typically, the afflicted patients present with complaints of progressive dyspnea and exercise intolerance. The typical functional picture of the 22 patients in this series revealed normal lung volumes. Only about 10% of the subjects had mild restrictive defects. The universal findings were mild to moderate hypoxemia, chronic respiratory alkalosis, high pulmonary vascular resistance and low cardiac output. Pathophysiological mechanisms responsible for dyspnea in chronic thromboembolic pulmonary hypertension are discussed.
authors.affiliation: III. Medizinische Klinik, Johannes-Gutenberg-Universität, Mainz.
authors.forename: B M
authors.initials: BM
authors.lastname: Fischer
authors.forename: M
authors.initials: M
authors.lastname: Kreiselmeyer
authors.forename: J
authors.initials: J
authors.lastname: Schlegel
authors.forename: S
authors.initials: S
authors.lastname: Schadmand
authors.forename: S
authors.initials: S
authors.lastname: Iversen
authors.forename: H J
authors.initials: HJ
authors.lastname: Rupprecht
authors.forename: J
authors.initials: J
authors.lastname: Lorenz
authors.forename: R
authors.initials: R
authors.lastname: Ferlinz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000503:physiopathology*; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011652:Pulmonary Circulation / Q000502:physiology; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000503:physiopathology*; D012129:Respiratory Function Tests
vernacular_title: Lungenfunktion bei chronisch persistierender Lungenembolie.