title: Hb Lepore (Pylos)/Hb S compounds heterozygosity in two Greek families.
abstract: We have studied three compound heterozygotes for Hb Lepore ("Pylos")/HbS hemoglobin, a combination quite uncommon in the literature. It is of interest that while two of these cases are clinically similar to those thus far reported, the third one is free of symptoms and the diagnosis was put incidentally. This mild condition may be due to the high level of fetal hemoglobin produced.
authors.affiliation: Thalassaemia Unit, Laikon Hospital, Athens, Greece.
authors.forename: E
authors.initials: E
authors.lastname: Voskaridou
authors.forename: K
authors.initials: K
authors.lastname: Konstantopoulos
authors.forename: P
authors.initials: P
authors.lastname: Kollia
authors.forename: M
authors.initials: M
authors.lastname: Papadakis
authors.forename: D
authors.initials: D
authors.lastname: Loukopoulos
mesh_terms: D000328:Adult; D006115:Greece / Q000453:epidemiology; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged; D010375:Pedigree
chemical_list: D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal; C083746:hemoglobin sickle-Lepore