title: [Perioperative blood gas analysis in 100 patients in spontaneous respiration treated with ND-YAG laser for endoluminal tracheo-bronchial neoplasms].
abstract: OBJECTIVE
  To determine the reliability on spontaneous ventilation of small continuously associated doses of ketamine and propofol during yag-laser therapy for upper airways neoplastic obstructions.
  
  
  METHODS
  Prospective description of blood gas analysis variation throughout the intervention and in the early postoperative period.
  
  
  METHODS
  Operating theatre and postoperative Intensive Care Unit of the National Institute for Cancer Research.
  
  
  METHODS
  A hundred consecutive cancer patients referred to our Institution for upper airways tumoral progressive obstruction.
  
  
  METHODS
  Yag-laser firing.
  
  
  RESULTS
  Pre-intra and postoperative blood gas analysis, BP, HR, Sat O2 have been registered every 10'. Mean intraoperative pCO2 rose to 47.3 mmHg (30-60), but within 2 to 3.20 hrs returned close to preoperative value (38.3 mmHg) allowing early patient discharge.
  
  
  CONCLUSIONS
  The i.v. association of 0.7-1.0 mg/kg Ketamine and 1 mg/kg propofol, followed by 5 micrograms/kg/h and 3 mg/kg/h respectively, turned out to be satisfactory for both patients and anaesthetists in terms of anaesthesia and spontaneous breathing maintenance during yag-laser firing for obstructive upper airways cancer patients.
authors.affiliation: Servizio di Anestesia e Rianimazione, Istituto Nazionale per la Ricerca sul Cancro, Genova.
authors.forename: L
authors.initials: L
authors.lastname: Mignone
authors.forename: F
authors.initials: F
authors.lastname: Nicosia
authors.forename: L
authors.initials: L
authors.lastname: Zappi
authors.forename: L
authors.initials: L
authors.lastname: Villani
authors.forename: C
authors.initials: C
authors.lastname: Russo
authors.forename: D
authors.initials: D
authors.lastname: Carrossino
authors.forename: A
authors.initials: A
authors.lastname: Verna
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001784:Blood Gas Analysis; D001984:Bronchial Neoplasms / Q000601:surgery*; D020680:Bronchoscopes; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D007649:Ketamine; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D015742:Propofol; D011446:Prospective Studies; D012119:Respiration; D014134:Tracheal Neoplasms / Q000601:surgery*
chemical_list: D007649:Ketamine; D015742:Propofol
vernacular_title: Valutazioni emogasanalitiche perioperatorie in 100 pazienti in ventilazione spontanea trattati con ND-YAG laser per neoplasie tracheo-bronchiali endoluminali.