[Value of immunodiagnosis by ELISA and Western blotting for the diagnostic and therapeutic management of neurocysticercosis].
The humoral immune response in neurocysticercosis was studied in seventy patients from the Reunion Island (Indian Ocean). In the serum and the cerebrospinal fluid, specific antibodies were quantified using an enzyme-linked (ELISA) and Western-blot (EITB) technique. It was found that two antigenic fractions, of 13 and 14kd molecular weight, are highly specific of an active disease, for which the treatment is recommended. This new result, established in the quite simple epidemiologic environment of the Reunion island, is under validation in Madagascar.
Simac
C
C
Laboratoire de Parasitologie, C.H. Saint-Pierre, La Réunion.
Michel
P
P
Andriantsimahavandy
A
A
Esterre
P
P
Michault
A
A
D000328:Adult; D000917:Antibody Formation; D015153:Blotting, Western; D002493:Central Nervous System Diseases / Q000097:blood / Q000134:cerebrospinal fluid / Q000276:immunology*; D003551:Cysticercosis / Q000097:blood / Q000134:cerebrospinal fluid / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008270:Madagascar; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed
Intérêt du diagnostic immunologique par ELISA et EITB pour la conduite diagnostique et therapeutique d'une neurocysticercose.