Consumption of soft drinks with phosphoric acid as a risk factor for the development of hypocalcemia in children: a case-control study.
A comparison of 57 cases (in children with serum calcium concentration < 2.2 mmol/L) and 171 controls (in children with serum calcium level > or = 2.2 mmol/L) was carried out to assess whether the intake of at least 1.5 L/wk of soft drinks containing phosphoric acid is a risk factor for the development of hypocalcemia. A significant association was found: odds ratio = 5.27; 95% confidence interval, 3.17 to 8.75; p < 0.001. The hypothesis of a causal relationship between intake of phosphoric acid-containing soft drinks and hypocalcemia warrants further investigation.
Mazariegos-Ramos
E
E
Hospital General de Zona No. 1 Durango, Mexico, Mexico City.
Guerrero-Romero
F
F
Rodríguez-Morán
M
M
Lazcano-Burciaga
G
G
Paniagua
R
R
Amato
D
D
D002253:Carbonated Beverages / Q000009:adverse effects*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology*; D008297:Male; D016017:Odds Ratio; D010756:Phosphoric Acids / Q000009:adverse effects*; D012307:Risk Factors; D012737:Sex Factors
D010756:Phosphoric Acids; C030242:phosphoric acid