title: Sudden death in elderly women with Fabry's disease.
abstract: We report two cases of elderly women who died unexpectedly. In both cases, light- and electron-microscopical examination proved a diagnosis of Fabry's disease. The major pathological changes were myocardial mottling, foamy vacuolation of myocytes and glomerular endothelial cells, and characteristic lamellar inclusions. Neither woman had either a personal or family history of Fabry's disease. Fabry's disease presenting as sudden death is very rare. We present the findings in two cases together with a review of literature particularly relevant to the cardiovascular system.
authors.affiliation: Department of Forensic Pathology, University of Sheffield, England.
authors.forename: N
authors.initials: N
authors.lastname: Carter
authors.forename: C M
authors.initials: CM
authors.lastname: Milroy
authors.forename: R T
authors.initials: RT
authors.lastname: Shepherd
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003645:Death, Sudden / Q000209:etiology*; D000795:Fabry Disease; D005260:Female; D006801:Humans; D008875:Middle Aged