Bloodstream infection due to Trichosporon beigelii in a burn patient: case report and review of therapy.
Trichosporon beigelii is a yeast that has recently been increasingly associated with systemic infections in immunocompromised patients. Few cases have been reported in nonleukopenic patients. We describe what we believe to be the first report of a bloodstream infection due to T. beigelii in a burn patient. Our patient was successfully treated with a combination of amphotericin B and flucytosine. Antifungal susceptibility testing of the T. beigelii isolate showed that the organism was inhibited but not killed by amphotericin B. Burn patients are known to have a transient defect in neutrophil function that can predispose them to some infections. We review the English-language literature of recently reported cases of trichosporonosis and review the various therapies for T. beigelii infection.
Hajjeh
R A
RA
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Blumberg
H M
HM
D000328:Adult; D002058:Burns, Electric / Q000150:complications*; D016469:Fungemia / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology*; D014250:Trichosporon