[The immunosuppressive activity of Streptococcus aureus peptidoglycan].
The immunosuppressive activity of peptidoglycan, obtained from S. aureus was studied in mouse experiments on the model of delayed hypersensitivity (DH) to guinea pig antigens. The study revealed that PG suppressed DH, this action being linked with its insoluble fraction. The soluble part of PG did not suppress DH. Experiments with the use of immunosorbent demonstrated the existence of serological similarity between the active factor of the soluble part of PG and its insoluble part.
Posur
V K
VK
Borisova
E V
EV
Furtat
I M
IM
Lolo
A A
AA
Borisov
V A
VA
D000818:Animals; D004926:Escherichia coli / Q000276:immunology; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007111:Immunity, Cellular / Q000187:drug effects; D007166:Immunosuppressive Agents / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*; D051379:Mice; D008808:Mice, Inbred CBA; D010457:Peptidoglycan / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*; D012475:Salmonella / Q000276:immunology; D012764:Shigella sonnei / Q000276:immunology; D012995:Solubility; D013154:Spleen / Q000276:immunology; D013211:Staphylococcus aureus; D013997:Time Factors
D007166:Immunosuppressive Agents; D010457:Peptidoglycan
Immunosupressivnaia aktivnost' peptidoglikana Staphylococcus aureus.