title: Alcohol and drug abuse in burn injuries.
abstract: Two studies are described in this paper. In the first study 225 acutely, severely burned patients were retrospectively investigated as to admission blood alcohol level and history of chronic alcohol abuse. The influence of further risk factors, circumstances and therapeutic data was studied, in particular the influence of gender, full-thickness burns, smoke inhalation injury, smoking, length of total and ICU stay, and suicide attempt. The 70 patients with positive blood alcohol levels on admission had a significantly higher fatality rate (31.5 per cent) in comparison with the 18.1 per cent fatality rate of patients with a negative blood alcohol level. Both groups had nearly identical mean TBSA and mean age. Chronic alcohol abuse was noted in 59 patients. These patients were found to have a higher fatality rate (31.4 per cent, 22/70) compared with that of patients without a history of chronic alcohol abuse who had an overall fatality rate of 18.1 per cent (28/155). No significant difference was found between non-intoxicated and acutely intoxicated alcoholics (31.4 vs 29.3 per cent). Our conclusion is that intake of alcohol before burn injury represents an independent risk factor. The second study was a prospective study of 16 consecutively admitted burn patients, who were evaluated for both drug and alcohol intake. Five patients had positive drug levels and five had positive alcohol levels. Five patients had a history of chronic drug and/or alcohol abuse. This incidence of alcohol and drug abuse supports the findings of our retrospective study.
authors.affiliation: Department of Plastic and Reconstructive Surgery with Burn Unit, City Hospital Cologne-Merheim, Koeln, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Haum
authors.forename: W
authors.initials: W
authors.lastname: Perbix
authors.forename: H J
authors.initials: HJ
authors.lastname: Häck
authors.forename: G B
authors.initials: GB
authors.lastname: Stark
authors.forename: G
authors.initials: G
authors.lastname: Spilker
authors.forename: M
authors.initials: M
authors.lastname: Doehn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications* / Q000453:epidemiology; D002056:Burns / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D015208:Smoke Inhalation Injury; D012907:Smoking; D019966:Substance-Related Disorders / Q000150:complications* / Q000453:epidemiology; D013406:Suicide, Attempted; D015996:Survival Rate