Cogan's syndrome: a new possible complication of antiphospholipid antibodies?
A 55-year-old woman with a six-year history of Sjögren's syndrome (SS) and the positivity of IgG and IgM antiphospholipid antibodies (aPL) developed a sudden onset of sensorineural hearing loss associated with vertigo. This suggested the presence of an atypical Cogan's syndrome (CS), which might be a focal, neurological complication of aPL.
Casoli
P
P
2nd Department of Medicine, Santa Maria Nuova Hospital, Reggio Emilia, Italy.
Tumiati
B
B
D017153:Antibodies, Anticardiolipin / Q000032:analysis*; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D004359:Drug Therapy, Combination; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D015423:Scleritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000276:immunology; D013577:Syndrome; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D014717:Vertigo / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology
D017153:Antibodies, Anticardiolipin; D017152:Antibodies, Antiphospholipid; D011241:Prednisone; D008727:Methotrexate