Ciprofloxacin-induced renal dysfunction in patients with mycobacterial lung infections.
3 patients with mycobacterial lung infections, one due to Mycobacterium avium-intracellulare and 2 due to M. tuberculosis, developed ciprofloxacin-induced acute renal dysfunction while receiving the drug together with other antimycobacterial agents. These episodes took place 8-10 days after commencement of therapy and recovered spontaneously after cessation of all antimycobacterial drugs for 2-8 weeks. No recurrence was noted when patients were restarted on regimens that did not contain ciprofloxacin.
Yew
W W
WW
Tuberculosis and Chest Unit, Grantham Hospital, Hong Kong.
Chau
C H
CH
Wong
P C
PC
Choi
H Y
HY
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D002939:Ciprofloxacin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D002939:Ciprofloxacin