title: Evaluation of optimal stent size after endourologic incision of ureteral strictures.
abstract: The stent size necessary to promote optimal ureteral healing after an endoureterotomy is not known. We compared healing of an endoureterotomy over a 7F indwelling ureteral stent with healing over a 14F endopyelotomy stent. A midureteral stricture was created in each of 25 anesthetized female minipigs using an electrified stone basket passed retrograde. Six weeks later, the stricture was incised with a 24F cutting balloon device. Twenty pigs were randomized to receive a 7F or a 14F stent; four control pigs received neither incisions nor stents. At 1 week, a radiograph was performed to confirm proper stent position, and the stents were removed. At 3 months, a retrograde ureterogram was performed, and the ureters were examined grossly and harvested for histologic studies. Two of the ten pigs in each study group developed a recurrent stricture. The use of a 14F stent provided no advantage over the use of a smaller, more easily positioned 7F stent.
authors.affiliation: Department of Surgery (Division of Urology), Washington University School of Medicine, St. Louis, MO, USA.
authors.forename: Y T
authors.initials: YT
authors.lastname: Moon
authors.forename: K
authors.initials: K
authors.lastname: Kerbl
authors.forename: M S
authors.initials: MS
authors.lastname: Pearle
authors.forename: S M
authors.initials: SM
authors.lastname: Gardner
authors.forename: E M
authors.initials: EM
authors.lastname: McDougall
authors.forename: P
authors.initials: P
authors.lastname: Humphrey
authors.forename: R V
authors.initials: RV
authors.lastname: Clayman
mesh_terms: D000818:Animals; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D005260:Female; D012008:Recurrence; D015607:Stents; D013552:Swine; D013556:Swine, Miniature; D016896:Treatment Outcome; D014517:Ureteral Obstruction / Q000150:complications / Q000473:pathology / Q000601:surgery*; D014552:Urinary Tract Infections / Q000150:complications / Q000382:microbiology; D014556:Urine / Q000382:microbiology