Trigeminal neuralgia in multiple sclerosis relieved by a prostaglandin E analogue.
Trigeminal neuralgia is an uncommon but troublesome symptom of multiple sclerosis that can be refractory to conventional treatments. Misoprostol, a long-acting prostaglandin E1 analogue, relieved pain in six of seven patients who had failed to respond to conventional pharmacologic therapy.
Reder
A T
AT
Department of Neurology, University of Chicago, IL 60637, USA.
Arnason
B G
BG
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016595:Misoprostol / Q000627:therapeutic use*; D009103:Multiple Sclerosis / Q000150:complications*; D011459:Prostaglandins E, Synthetic; D014277:Trigeminal Neuralgia / Q000150:complications / Q000188:drug therapy*
D011459:Prostaglandins E, Synthetic; D016595:Misoprostol