title: Post-implantation fasting does not induce pregnancy failure in newly inseminated mice.
abstract: The effect of food deprivation on the rate of pregnancy failure in newly inseminated mice was evaluated. The pre-implantation fasting for 48 h beginning on day 4 or 5 postcoitum induced a high rate of pregnancy failure in newly inseminated females. However, fasting for 48 h on day 6 had a moderate effect in inducing pregnancy failure. By contrast, females which were deprived of food on day 7 postcoitum exhibited a significant reduction in the rate of pregnancy failure. Pre-implantation fasting was highly effective in inducing pregnancy failure compared to that of post-implantation fasting. The results suggest that fasting (i.e. day 4 or 5 postcoitum)--induced depression in prolactin has resulted in failure of pregnancy and fasting at post-implantation period (i.e. day 6 or after postcoitum) has not been interfered with progesterone production by placenta.
authors.affiliation: Department of Endocrinology, University of Madras, Taramani, India.
authors.forename: G
authors.initials: G
authors.lastname: Archunan
authors.forename: M M
authors.initials: MM
authors.lastname: Aruldhas
authors.forename: P
authors.initials: P
authors.lastname: Govindarajulu
mesh_terms: D000818:Animals; D010064:Embryo Implantation / Q000502:physiology; D047108:Embryonic Development / Q000502:physiology*; D005215:Fasting / Q000009:adverse effects*; D005260:Female; D007314:Insemination / Q000502:physiology; D051379:Mice; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D013997:Time Factors