title: Intracerebral haemorrhage due to amphetamine abuse: report of two cases with underlying arteriovenous malformations.
abstract: Amphetamine abuse may be complicated by intracerebral, subdural or subarachnoid haemorrhage. The causative mechanism is probably a combination of vasculitis and induced hypertension. Most cases of intracerebral haemorrhage are subcortical. Only one case of amphetamine-induced intracerebral haematoma where there was also an underlying arteriovenous malformation has been previously reported. We report two cases of intracerebral haematoma due to amphetamine abuse whether an underlying AVM was found at the time of surgery. This possibility should be considered in cases of amphetamine-induced intracerebral haemorrhage.
authors.affiliation: Department of Neurosurgery, University Hospital of Wales, Cardiff, UK.
authors.forename: F
authors.initials: F
authors.lastname: Selmi
authors.forename: K G
authors.initials: KG
authors.lastname: Davies
authors.forename: R R
authors.initials: RR
authors.lastname: Sharma
authors.forename: J W
authors.initials: JW
authors.lastname: Neal
mesh_terms: D000328:Adult; D000661:Amphetamine / Q000009:adverse effects*; D002540:Cerebral Cortex / Q000098:blood supply / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000601:surgery; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000601:surgery; D008694:Methamphetamine / Q000009:adverse effects; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D008694:Methamphetamine; D000661:Amphetamine; D018817:N-Methyl-3,4-methylenedioxyamphetamine