Serum lipid, apolipoprotein and lipoparticle levels in the human fetus.
Blood collected from 62 fetuses aged 20-38 weeks of gestation was studied. The values of ten lipid parameters were determined: cholesterol (TC), triglycerides (TGs), apolipoprotein A1 (apo A1), apolipoprotein B (apo B), apolipoprotein E (apo E), total apolipoprotein CIII (apo CIII), apolipoprotein CIII present in particles containing apo B (apo CIII LpB) or not (apo CIII Lp non-B), lipoparticles A1 (LpA1), and lipoprotein a (Lp(a)). The results show that, except for apo E, all the studied parameters were present in lower concentrations than in adults and newborns, and that Lp(a) is not detectable at that stage in life.
Legras
B
B
Biochemistry Laboratory, Hôpital Sud, Rennes, France.
Durou
M R
MR
Ruelland
A
A
Gallou
G
G
Jezequel
C
C
Cloarec
L
L
D000293:Adolescent; D000328:Adult; D001053:Apolipoproteins / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn / Q000097:blood; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D011247:Pregnancy; D012016:Reference Values
D001053:Apolipoproteins; D008055:Lipids; D008074:Lipoproteins