[The epidermal growth factor induces specific changes in the expression of small RNA and of the set of small RNP in A-431 cells].
Specific small ribonucleoprotein (alpha-RNP) complexes have been identified and characterized in the human epidermal carcinoma A-431 cells. The alpha-RNP complexes contain Alu-homologous small RNA, along with other small antisense RNA species. The epidermal growth factor (EGF) has been shown to induce selective specific changes in the expression of the small alpha-RNAs, the expression of the Alu-like RNA being repressed. Specific changes in the protein composition of the alpha-RNP complexes have been detected under the influence of EGF.
Konstantinova
I M
IM
Kulichkova
V A
VA
Turoverova
L V
LV
Petukhova
O A
OA
Kozhukharova
I V
IV
Teslenko
L A
LA
D002294:Carcinoma, Squamous Cell / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D006801:Humans; D009693:Nucleic Acid Hybridization; D012334:RNA, Neoplasm / Q000235:genetics; D012342:RNA, Small Nuclear / Q000032:analysis / Q000187:drug effects* / Q000302:isolation & purification; D017411:Ribonucleoproteins, Small Nuclear / Q000032:analysis / Q000187:drug effects* / Q000302:isolation & purification; D014407:Tumor Cells, Cultured
D004273:DNA, Neoplasm; D012334:RNA, Neoplasm; D012342:RNA, Small Nuclear; D017411:Ribonucleoproteins, Small Nuclear; D004815:Epidermal Growth Factor
Epidermal'nyĭ faktor rosta vyzyvaet spetsificheskie izmeneniia ékspressii malykh RNK i nabora belkov malykh RNP v kletkakh A-431.