title: [Langerhans-cell histiocytosis in an adult with initial vulvar involvement: 2 cases].
abstract: Langerhans' histiocytosis is a proliferation of atypical Langerhans cells which may affect several different organs. Two women had lesions of the vulva which led to the diagnosis. Vulvular involvement is the most frequent in gynaecological localization of Langerhans' histiocytosis. Pathological and immunohistochemical tests confirm the diagnosis.
authors: Service de Dermatologie, Hôpital Trousseau, CHU, Tours.
authors: E
authors: E
authors: Estève
authors: F
authors: F
authors: Pruvost
authors: P
authors: P
authors: Bensaïd
authors: M C
authors: MC
authors: Machet
authors: A
authors: A
authors: de Muret
authors: L
authors: L
authors: Vaillant
authors: G
authors: G
authors: Lorette
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008466:Mechlorethamine / Q000627:therapeutic use; D008875:Middle Aged; D014456:Ulcer / Q000473:pathology; D014845:Vulvar Diseases / Q000188:drug therapy / Q000473:pathology*
chemical_list: D008466:Mechlorethamine
vernacular_title: Histiocytose langerhansienne de l'adulte avec atteinte vulvaire initiale: 2 cas.