Steatocrit: a reliable semiquantitative method for detection of steatorrhea.
Steatocrit is a semiquantitative method for determination of fat content in fecal samples. Previous studies, mostly performed in children, reported controversial results. The aim of our study was to compare the determination of fat content in 148 fecal samples by two methods: the conventional van de Kamer and the steatocrit. Seventy-seven fecal samples had steatorrhea (> 7 g/day). The upper normal limit for the steatocrit (determined by the mean +/- 2 SD of samples without steatorrhea) was 2.1%. The steatocrit showed a sensitivity of 87%, specificity of 97%, and positive and negative predictive values of 97 and 87%, respectively. When fecal fat excretion > 20 g/day was evaluated, sensitivity increased to 98%. A significant linear correlation was found between steatocrit and the quantitative chemical method (r = 0.80; p < 0.0001). In conclusion, the steatocrit is satisfactory in the discrimination of patients with and without fat malabsorption. It is a simple, rapid, inexpensive, and reliable semiquantitative test that can be used when other methods are impractical.
Sugai
E
E
Hospital de Gastroenterologia, Universidad del Salvador, Buenos Aires, Argentina.
Srur
G
G
Vazquez
H
H
Benito
F
F
Mauriño
E
E
Boerr
L A
LA
Bai
J C
JC
D000328:Adult; D002446:Celiac Disease / Q000175:diagnosis*; D002624:Chemistry, Clinical / Q000379:methods; D002648:Child; D005243:Feces / Q000737:chemistry*; D005260:Female; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008297:Male; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D008055:Lipids