title: [Renal manifestation in POEMS syndrome].
abstract: The authors report four cases of POEMS Syndrome with renal involvement. Two had renal failure and mild proteinuria. The two others had hyporeninemic hypoaldosteronism with type IV renal tubular acidosis in the first and hyperkalemia alone in the second. In the two cases, renal biopsy showed mesangial proliferation. Evolution was favourable when the plasma cell proliferation could be checked. In POEMS pathophysiology of renal involvement remains unknown. Soluble factor(s) produced by plasma cells may be responsible for most signs and symptoms perhaps as a result of increased vascular permeability.
authors: Service de rhumatologie, Hôpital G. Montpied, Clermont-Ferrand.
authors: M
authors: M
authors: Soubrier
authors: P
authors: P
authors: Deteix
authors: G
authors: G
authors: Derray
authors: J J
authors: JJ
authors: Dubost
authors: B
authors: B
authors: Sauvezie
authors: A
authors: A
authors: Chapman
authors: J L
authors: JL
authors: Bussière
mesh_terms: D000141:Acidosis, Renal Tubular / Q000209:etiology; D000368:Aged; D005260:Female; D006801:Humans; D006994:Hypoaldosteronism / Q000209:etiology; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D016878:POEMS Syndrome / Q000150:complications*; D011507:Proteinuria / Q000209:etiology; D051437:Renal Insufficiency / Q000209:etiology
vernacular_title: Manifestations rénales du syndrome POEMS.