Alternatives to ECMO.
The past decade has witnessed technological advancements which are unparalleled in neonatology. ECMO has been demonstrated to be a powerful rescue treatment, but has perhaps been overutilised and is not universally available. Alternative treatments have been shown to be both safe and efficacious in the management of infants with respiratory failure. Direct head to head clinical trials will probably be necessary to establish appropriate criteria and indications for use, given the wide diversity of pathophysiology these unique patients present.
Donn
S M
SM
Holden Neonatal Intensive Care Unit, University of Michigan Medical Center, Ann Arbor 48109-0254.
D015199:Extracorporeal Membrane Oxygenation; D006611:High-Frequency Jet Ventilation; D006801:Humans; D007231:Infant, Newborn; D008278:Magnesium Sulfate / Q000627:therapeutic use; D009569:Nitric Oxide / Q000627:therapeutic use; D010547:Persistent Fetal Circulation Syndrome / Q000628:therapy; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000628:therapy*
D009569:Nitric Oxide; D008278:Magnesium Sulfate