title: Diagnostic and prognostic significance of serum and tissue trace elements in breast malignancy.
abstract: 50 cases of breast malignancy constituted the study group. 26 age and sex matched formed the control group. Serum and tissue trace element viz copper, zinc, selenium and molybdenum levels were estimated by atomic absorption photometry. The study group showed significant hypercupremia and molybdenemia, hypozincaemia and hyposeleniamia. The reversal of trend was documented after therapy. The tissue level of copper and molybdenum was high and zinc and selenium was low. An association between serum and tissue level of trace element, stage, histological differentiation was observed. It was postulated that levels of trace elements may help in diagnosis and prognosis of disease.
authors: Dept of Surgery, MLN Med College, Alahabad.
authors: K
authors: K
authors: Sharma
authors: D K
authors: DK
authors: Mittal
authors: R C
authors: RC
authors: Kesarwani
authors: V P
authors: VP
authors: Kamboj
authors: Chowdhery
mesh_terms: D001940:Breast / Q000737:chemistry; D001943:Breast Neoplasms / Q000737:chemistry* / Q000175:diagnosis / Q000628:therapy; D018567:Breast Neoplasms, Male / Q000737:chemistry / Q000175:diagnosis / Q000628:therapy; D003300:Copper / Q000032:analysis / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008982:Molybdenum / Q000032:analysis / Q000097:blood; D012643:Selenium / Q000032:analysis / Q000097:blood; D014131:Trace Elements / Q000032:analysis* / Q000097:blood; D015032:Zinc / Q000032:analysis / Q000097:blood
chemical_list: D014131:Trace Elements; D003300:Copper; D008982:Molybdenum; D012643:Selenium; D015032:Zinc