Population based survival rates for childhood cancer in Britain, 1980-91.
OBJECTIVE
To investigate the survival of children with cancer diagnosed during 1980-91 in order to assess the impact of developments in medical care on a population basis.


METHODS
Retrospective cohort study.


METHODS
Great Britain.


METHODS
14973 children with cancer diagnosed during 1980-91 and included in the population based National Registry of Childhood Tumours.


METHODS
Actuarial survival rates.


RESULTS
For all cancers combined, two year survival increased from 66% to 76% between 1980-2 and 1989-91, and five year survival increased from 57% to 65% between 1980-2 and 1986-8. Significant increases in survival rates occurred among children with acute lymphoblastic leukaemia, acute nonlymphocytic leukaemia, retinoblastoma, osteosarcoma, Ewing's sarcoma, rhabdomyosarcoma, and malignant gonadal germ cell tumours. No trend in survival was seen for children with Hodgkin's disease, central nervous system tumours, neuroblastoma, or Wilms's tumour.


CONCLUSIONS
Nearly two thirds of children who have cancer diagnosed can now expect to survive at least 10 years.
Stiller
C A
CA
Department of Paediatrics, University of Oxford.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007938:Leukemia / Q000401:mortality; D008223:Lymphoma / Q000401:mortality; D008297:Male; D009026:Mortality / Q000639:trends; D009369:Neoplasms / Q000401:mortality*; D009373:Neoplasms, Germ Cell and Embryonal / Q000401:mortality; D009423:Nervous System Neoplasms / Q000401:mortality; D012042:Registries; D012189:Retrospective Studies; D012509:Sarcoma / Q000401:mortality; D015996:Survival Rate; D006113:United Kingdom / Q000453:epidemiology