title: Absolute glutathione requirement for sporulation of a yeast Saccharomyces cerevisiae.
abstract: The glutathione (GSH)-deficient yeast cells of Saccharomyces cerevisiae completely failed to sporulate in nutrition-deprived medium containing potassium acetate (SPO medium). The sporulation defect of the yeast was restored only when the yeast cells were incubated in SPO medium in the presence of GSH or its derivative such as oxidized GSH and gamma-L-glutamyl-L-cysteine. It was concluded that GSH was indispensably required to enter into meiosis and/or sporulation processes of the yeast Saccharomyces cerevisiae.
authors: Gekkeikan Institute, Gekkeikan Co., Ltd., Kyoto, Japan.
authors: T
authors: T
authors: Suizu
authors: H
authors: H
authors: Tsutsumi
authors: Y
authors: Y
authors: Ohtake
authors: A
authors: A
authors: Kawado
authors: S
authors: S
authors: Imayasu
authors: A
authors: A
authors: Kimura
authors: K
authors: K
authors: Murata
mesh_terms: D000085:Acetates / Q000494:pharmacology; D019342:Acetic Acid; D003470:Culture Media; D005978:Glutathione / Q000031:analogs & derivatives / Q000494:pharmacology* / Q000502:physiology; D019803:Glutathione Disulfide; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D013172:Spores, Fungal / Q000187:drug effects / Q000502:physiology
chemical_list: D000085:Acetates; D003470:Culture Media; D005978:Glutathione; D019342:Acetic Acid; D019803:Glutathione Disulfide