title: [Results of proton therapy in the treatment of pituitary prolactin-secreting adenomas].
abstract: The paper presents follow-up results of narrow-beam proton therapy (1000 MeV) in 75 female patients suffering from prolactin-secreting pituitary adenomas. Prolactin concentrations reduced both in macro- and microprolactinomas patients. The response was achieved in 96% of the cases in adenoma stages I-IIIa. Such results are superior to those reached with other treatment modalities. The efficacy of the above proton treatment can be raised by adjuvant use of chemotherapy.
authors: B A
authors: BA
authors: Konnov
authors: N A
authors: NA
authors: Lebedeva
authors: T V
authors: TV
authors: Pushkareva
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009367:Neoplasm Staging; D010911:Pituitary Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D015175:Prolactinoma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D061766:Proton Therapy; D011879:Radiotherapy Dosage; D012074:Remission Induction; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Rezultaty protonnoĭ terapii prolaktinsekretiruiushchikh adenom gipofiza.