Clinical use of homograft stored by vitrification.
Using 20% DMSO and 6% propylene glycol in Kreb' Ringer phosphate solution as cryopotective agent for homograft vitrification storage, the viability of stored homograft (79.2%) was higher than that of slow cooling storage (59.7%). About 540000 cm2 of vitrified homograft were used to cover the wounds after excision of burn eschar in 135 patients with major burns. The take-rate was over 94%. The cryopreservation of skin by vitrification can improve the viability and quality of skin and save time and cost.
Zhu
Z M
ZM
Burn Unit, 304th Hospital, Beijing.
Jia
X M
XM
Chai
J K
JK
Gao
W Y
WY
Kong
Q H
QH
D000328:Adult; D002056:Burns / Q000601:surgery*; D015925:Cryopreservation / Q000379:methods*; D003451:Cryoprotective Agents; D004121:Dimethyl Sulfoxide; D006085:Graft Survival; D006801:Humans; D008297:Male; D019946:Propylene Glycol; D011409:Propylene Glycols; D012867:Skin; D016038:Skin Transplantation
D003451:Cryoprotective Agents; D011409:Propylene Glycols; D019946:Propylene Glycol; D004121:Dimethyl Sulfoxide