Renal dysfunction in patients of kala azar treated with sodium antimony gluconate.
We studied 27 patients presenting with renal dysfunction after Stibamate therapy. Eighteen patients were proved cases of Kala Azar, others of PUO. Out of 10 cases in whom Kidney biopsy was done, 6 had tubular necrosis, one had mild mesangial proliferation and 3 had normal picture.
Rai
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Dept. of Biochemistry, I.G.I.M.S., Sheikhpura, Patna, India.
Kumar
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Kumar
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D000293:Adolescent; D000328:Adult; D000967:Antimony Sodium Gluconate / Q000009:adverse effects* / Q000627:therapeutic use; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D005260:Female; D005335:Fever of Unknown Origin / Q000188:drug therapy; D005920:Glomerular Mesangium / Q000187:drug effects / Q000473:pathology; D005921:Glomerulonephritis / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000473:pathology / Q000652:urine; D007683:Kidney Tubular Necrosis, Acute / Q000139:chemically induced / Q000473:pathology; D007898:Leishmaniasis, Visceral / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000652:urine; D012964:Sodium / Q000652:urine
D012964:Sodium; D003404:Creatinine; D000967:Antimony Sodium Gluconate