title: Effect of procainamide on platelet adhesion in rats.
abstract: Effect of procainamide on platelet adhesion in rats was studied with the improved rotating glass sphere method. Procainamide of 136.0, 34.0, 8.5 mumol.L-1 in vitro and 10 mg.kg-1 in vivo inhibited significantly the platelet adhesion with the inhibitory rates of 56%, 28%, 8%, and 24%, respectively. It showed that procainamide given in vitro or in vivo produced an inhibition on platelet adhesion.
authors: Department of Physics, First Military Medical University, Guangzhou, China.
authors: Y S
authors: YS
authors: Yang
authors: Y X
authors: YX
authors: Zhou
authors: F B
authors: FB
authors: Ma
authors: C W
authors: CW
authors: Shan
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D010973:Platelet Adhesiveness / Q000187:drug effects*; D011342:Procainamide / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D011342:Procainamide