title: [A case of pulmonary metastasis from colon cancer successfully treated with high-dose 5'-DFUR].
abstract: We report a case, showing a complete response to high-dose 5'-DFUR, with pulmonary metastasis from colon cancer. A 52-year-old male patient underwent right hemicolectomy for ascending colon cancer in August, 1991. A recurrence of colon cancer developed in the left lower lung 16 months after surgery, and 5'-DFUR was administered at a dose of 1,600 mg/body/day. The pulmonary metastatic lesion was undetectable on chest X-ray film 9 weeks after the start of this therapy. The dose of 5'-DFUR was then reduced to 600 mg/body/day. Although this condition was maintained for 22 weeks, chest X-ray film again showed the metastatic lesion at the same site in the lung as before. The pulmonary metastasis was resected completely in April, 1994. This is suggested to be an effective therapy for pulmonary metastasis from colon cancer.
authors: Dept. of Surgery, Toyonaka Municipal Hospital.
authors: T
authors: T
authors: Fujimoto
authors: M
authors: M
authors: Takami
authors: Y
authors: Y
authors: Okumura
authors: T
authors: T
authors: Takada
authors: M
authors: M
authors: Kitada
authors: Y
authors: Y
authors: Tsukahara
authors: T
authors: T
authors: Shibata
authors: M
authors: M
authors: Murotani
authors: K
authors: K
authors: Iihara
authors: T
authors: T
authors: Watanabe
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D003082:Colectomy; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005467:Floxuridine / Q000008:administration & dosage*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D012074:Remission Induction
chemical_list: D000970:Antineoplastic Agents; D005467:Floxuridine; C025034:doxifluridine