Congenital marked hypertrichosis and Laband syndrome in a child: overlap between the gingival fibromatosis-hypertrichosis and Laband syndromes.
Gingival fibromatosis may be reported as an isolated finding or associated with a number of distinct and frequently inherited group of disorders. The characteristics of the Laband syndrome include gingival hyperplasia, dysplasia of the terminal phalanges and nails of extremities, hepatosplenomegaly and facial dysmorphism. Another well-known syndrome with gingival fibromatosis associates generalized hypertrichosis and inconstant mental retardation and epilepsy. We report a case with features of Laband syndrome and congenital marked hypertrichosis, suggesting overlap between these two genetic disorders.
Lacombe
D
D
Department of Pediatric Genetics, Pellegrin-Children's Hospital, Bordeaux, France.
Bioulac-Sage
P
P
Sibout
M
M
Daussac
E
E
Lesure
F
F
Manchart
J P
JP
Battin
J
J
D000015:Abnormalities, Multiple / Q000235:genetics*; D001706:Biopsy; D005147:Facial Bones / Q000002:abnormalities; D005260:Female; D005351:Fibromatosis, Gingival / Q000235:genetics*; D005885:Gingival Hyperplasia / Q000235:genetics*; D006228:Hand Deformities, Congenital / Q000235:genetics*; D006529:Hepatomegaly / Q000235:genetics*; D006801:Humans; D006983:Hypertrichosis / Q000235:genetics*; D007194:India; D007231:Infant, Newborn; D012867:Skin / Q000473:pathology; D013163:Splenomegaly / Q000235:genetics*; D013577:Syndrome