Squamous cell carcinoma arising in Hashimoto's thyroiditis.
The case of a 76-year-old white woman with squamous cell carcinoma of the thyroid gland arising in a background of Hashimoto's thyroiditis is presented. Squamous cell carcinoma of the thyroid gland is a very rare and aggressive tumor, and only a few cases are reported as arising in Hashimoto's thyroiditis. Although Hashimoto's thyroiditis alone does not necessarily predispose patients to malignancy, the finding of a prominent nodule in such a patient should suggest the possibility of malignancy, and an aggressive search and treatment regimen, including surgical intervention, should be pursued.
Chaudhary
R K
RK
Department of Surgery, University of Pittsburgh, Pennsylvania 15213.
Barnes
E L
EL
Myers
E N
EN
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D013967:Thyroiditis, Autoimmune / Q000150:complications*