title: Evaluation of a cytological scoring system for predicting histological grade and disease-free survival in primary breast cancer.
abstract: A simple cytological scoring system was evaluated as a method of predicting histological grade and disease-free survival in 79 patients with primary breast cancer. The mitotic activity index and oestrogen receptor status were also assessed for their predictive value. The concordance between cytological scores and histological grades was good (80%) for low-grade lesions, but poor (45%) for high-grade lesions. Similar results were found using the mitotic activity index as a prognostic indicator. Cytological grading was not found to be an independent prognostic indicator after a median follow up of 8 years.
authors: Department of Histopathology, Sophia Hospital, Zwolle, The Netherlands.
authors: H
authors: H
authors: de Graaf
authors: P
authors: P
authors: Willemse
authors: B E
authors: BE
authors: Laddé
authors: H A
authors: HA
authors: Van den Bergen
authors: M
authors: M
authors: Krebber
authors: T
authors: T
authors: Tjabbes
authors: W J
authors: WJ
authors: Sluiter
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D008938:Mitosis; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*; D012189:Retrospective Studies
chemical_list: D011960:Receptors, Estrogen