title: [The COMOD system. A preservative-free multidose container for eyedrops].
abstract: BACKGROUND
  The newly developed COMOD -system is a multi-dose-container for eye drops which makes the addition of preservatives unnecessary. In this study we investigated the microbiological safety of the COMOD -system which was used in action for the first time.
  
  
  METHODS
  After cataract surgery 97 patients only used unpreserved, dexamethason-containing eye drops in COMOD -bottles for two days in hospital and for five more days at home. The used bottle were examined microbiologically afterwards.
  
  
  RESULTS
  No COMOD -bottle showed a microbiologically serious contamination; no patient showed an unusual healing process which would have been typical for any infection. Concerning the handling it turned out during use in hospital that the hand-made prototypes have to be improves. The vast majority of patients managed the handling at home well, independent of sex or age.
  
  
  CONCLUSIONS
  The COMOD -system is a suitable microbiologically safe container for unpreserved eye drops.
authors: Augenklinik, Saarbrücker Winterbergkliniken.
authors: C
authors: C
authors: Teping
authors: B
authors: B
authors: Wiedemann
mesh_terms: D002387:Cataract Extraction; D003907:Dexamethasone / Q000008:administration & dosage*; D004340:Drug Contamination; D004349:Drug Packaging; D004867:Equipment Design; D006801:Humans; D009883:Ophthalmic Solutions; D011182:Postoperative Care; D014945:Wound Healing / Q000187:drug effects
chemical_list: D009883:Ophthalmic Solutions; D003907:Dexamethasone
vernacular_title: Das COMOD-System. Ein konservierungsmittelfreies Mehrdosenbehältnis für Augentropfen.