[Relation between the heart and lungs in children and adolescents with ventricular septal defects].
Lung function tests were performed in 39 patients with haemodynamically significant ventricular septal defect (age 3-20 years, median 10 years). We found pulmonary restriction in 47% of patients, pulmonary hyperinflation in 50% of patients, obstruction of smaller airways in 20% of patients preoperatively. Observed lung function disorders were not related to the volume of the left to right shunt and the mean pulmonary arterial pressure. The surgical correction of VSD lead only to significant improvement of hyperinflation. The rest abnormal findings persisted for several years postoperatively. We conclude that the surgical repair of significant ventricular septal defect beyond 9.5 years of age does not prevent chronic lungs changes. The clinical implications of these findings yet remain to be established.
Havelová
L
L
Kardiocentrum Detskej fakultnej nemocnice v Bratislave.
D000293:Adolescent; D000328:Adult; D002648:Child; D006345:Heart Septal Defects, Ventricular / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D011652:Pulmonary Circulation; D015656:Respiratory Mechanics
Vzt'ah srdce-pl'úca u detí a mladistvých s defektom komorového septa.