title: End-tidal carbon dioxide during out-of-hospital cardiac arrest resuscitation: comparison of active compression-decompression and standard CPR.
abstract: OBJECTIVE
  To compare the maximal end-tidal carbon dioxide pressure (ETCO2 peak) values obtained during standard (S-CPR) and active compression-decompression CPR (ACD-CPR) during prolonged resuscitation in out-of-hospital cardiac arrest.
  
  
  METHODS
  Prospective, randomized crossover study.
  
  
  METHODS
  City with a population of 3.5 million, served by an emergency medical service system providing advanced cardiac life support.
  
  
  METHODS
  Patients with nontraumatic out-of-hospital cardiac arrest.
  
  
  METHODS
  Patients were randomly assigned to receive first, for a period of 3 minutes, either ACD-CPR or S-CPR; then the two methods were alternated. ETCO2 was continuously monitored and computed.
  
  
  RESULTS
  Sixteen patients (48 +/- 20 years old) were included; in 12, return of spontaneous circulation was achieved, and 5 were admitted alive to the hospital. A statistically significant increase in ETCO2 peak was obtained with ACD-CPR (27.6 +/- 3 mm Hg) compared with S-CPR (15.6 +/- 2.2 mm Hg). No major adverse effect possibly related to ACD-CPR was observed.
  
  
  CONCLUSIONS
  This prospective study suggests that ACD-CPR may improve cardiac output compared with S-CPR.
authors: Service d'Aide Médicale Urgente (SAMU) de Paris, Department of Anesthesiology, Hôpital Necker.
authors: G A
authors: GA
authors: Orliaguet
authors: P A
authors: PA
authors: Carli
authors: A
authors: A
authors: Rozenberg
authors: D
authors: D
authors: Janniere
authors: P
authors: P
authors: Sauval
authors: P
authors: P
authors: Delpech
mesh_terms: D000328:Adult; D000368:Aged; D002245:Carbon Dioxide; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D018592:Cross-Over Studies; D004632:Emergency Medical Services; D005260:Female; D006323:Heart Arrest / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012119:Respiration; D013990:Tidal Volume
chemical_list: D002245:Carbon Dioxide