[The role of the sex hormones in regulating the spermatogenesis process in different strains of mice irradiated at low doses of gamma quanta].
Intact BALB/c and CBA mice distinct in the total number of germ cells and testosterone level in blood plasma were exposed to doses of 0.1 and 0.25 Gy. Being tested 4-8 days after irradiation the BALB/c mice display compensatory-protective reaction which promote the maintenance of the germ cell number by active division of all spermatogonia types including the reserve ones. The CBA mice use the reserve later and only when the cells have reduced their proliferation activity or died. Testosterone plays a significant role in the process as the increase in its concentration stimulates proliferation activity and promotes mitosis block.
Mamina
V P
VP
D000818:Animals; D000242:Cyclic AMP / Q000097:blood / Q000528:radiation effects; D006152:Cyclic GMP / Q000097:blood / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C / Q000502:physiology*; D008808:Mice, Inbred CBA / Q000502:physiology*; D011836:Radiation Tolerance / Q000502:physiology; D013091:Spermatogenesis / Q000502:physiology / Q000528:radiation effects*; D013739:Testosterone / Q000097:blood / Q000528:radiation effects*; D013997:Time Factors
D013739:Testosterone; D000242:Cyclic AMP; D006152:Cyclic GMP
Rol' polovykh gormonov v reguliatsii protsessa spermatogeneza u mysheĭ raznykh liniĭ, obluchennykh v malykh dozakh gamma-kvantami.