title: [Type II Charcot-Marie-Tooth and dopa-sensitive Parkinson disease].
abstract: The occurrence of a dopa-sensitive parkinsonian syndrome 25 years after a neuropathy suggestive of Charcot-Marie-Tooth disease type II raised the possibility of a relationship between these two diseases. Apart from Machado-Joseph-Azorean disease, an association of this kind seems to be exceptional and it can not be excluded that it was fortuitous. However, the recent description of 7 familial and sporadic cases of a syndrome characterized by a peripheral neuropathy, familial in 5 of the 7 cases, followed, a few years later, by a dopa-sensitive parkinsonian syndrome, makes it possible to consider that this association might have a common genetic origin.
authors: Service de Neurologie II, Hôpitaux Universitaires de Strasbourg.
authors: C
authors: C
authors: Tranchant
authors: D
authors: D
authors: Ruh
authors: J M
authors: JM
authors: Warter
mesh_terms: D002607:Charcot-Marie-Tooth Disease / Q000150:complications*; D004295:Dihydroxyphenylalanine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010302:Parkinson Disease, Secondary / Q000150:complications* / Q000188:drug therapy
chemical_list: D004295:Dihydroxyphenylalanine
vernacular_title: Maladie de Charcot-Marie-Tooth type II et syndrome parkinsonien dopasensible.