Malignant lymphoma of the esophagus associated with macroglobulinemia: report of a case.
A case of non-Hodgkin's lymphoma of the esophagus in a 74 year old man is presented. Grossly, the surgically removed esophagus had a fusiform submucosal mass covered with smooth surfaced mucosa. Microscopic examination revealed that the mass consisted of a dense infiltrate of small to medium-sized lymphoid cells with plasmacytoid differentiation, leading to a diagnosis of diffuse small cell lymphoma with lymphoplasmacytic subtype. Laboratory data as well as immunohistochemical studies proved that the lymphoma produced monoclonal immunoglobulin M, giving rise to macroglobulinemia.
Kurihara
K
K
Department of Pathology, Uwajima City Hospital, Japan.
Fukui
A
A
Kumano
S
S
D000368:Aged; D004938:Esophageal Neoplasms / Q000276:immunology* / Q000473:pathology; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology* / Q000473:pathology; D008297:Male; D008258:Waldenstrom Macroglobulinemia / Q000209:etiology*