Toxicity of new spinal agents.
The clinical success of perispinal administration of opiates for pain relief has demonstrated the power of manipulating the neurochemistry of the spinal cord. This article briefly discussed reasons for increased interest in new spinal agents and some of the issues associated with determining their clinical safety.
Collins
J G
JG
Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut.
D000701:Analgesics, Opioid / Q000633:toxicity*; D000775:Anesthesia, Spinal / Q000009:adverse effects*; D000818:Animals; D006801:Humans
D000701:Analgesics, Opioid