title: A prospective evaluation of sensitivity and specificity of the ankle/brachial index in the follow-up of superficial femoral artery occlusions treated by angioplasty.
abstract: The aim of this study was to provide estimates of sensitivity and specificity of clinical history, pulses, and ankle/brachial index (ABI) in the follow-up of atherosclerotic occlusions of the superficial femoral artery treated by peripheral transluminal angioplasty (PTA). A total of 116 patients were followed prospectively for 1 year after angioplasty with follow-up visits immediately after angioplasty, and at 3, 6, and 12 months. All patients underwent digital subtraction angiography after 1 year of if they reported a deterioration of their symptoms. Reobstruction was defined as reocclusion or as restenosis exceeding 70%. Patency rates were calculated separately by clinical and ankle/brachial criteria; sensitivity and specificity were derived using angiography as standard. The presence or absence of pulses distal to the treated vessel segment had a sensitivity of 78% and a specificity of 66% for a reocclusion or significant restenosis; subjective complaints evaluated by history had a sensitivity of 83% and a specificity of 51%. The sensitivity of the ABI was 72% and 66%, with a specificity of 82% and 100% for cutoff values of 0.10 and 0.15, respectively. One year after PTA the angiographic patency rate was 39% +/- 5%; the patency rate based on ABI criteria 34% +/- 5%. A deterioration in the ABI by 0.15 indicated with reasonable certainty a reocclusion or significant restenosis whereas the sensitivity of the ABI was poor in detecting significant restenosis after PTA of occlusions of the superficial femoral artery. When only clinical criteria were used, the true patency rate was significantly overestimated as more than half of all reobstructions remained asymptomatic.
authors: Medizinische Universitätsklinik Graz, Abteilung für Angiologie, Karl-Franzens Universität Graz, Austria.
authors: M
authors: M
authors: Decrinis
authors: S
authors: S
authors: Doder
authors: G
authors: G
authors: Stark
authors: E
authors: E
authors: Pilger
mesh_terms: D015901:Angiography, Digital Subtraction; D000800:Angioplasty, Balloon; D000842:Ankle / Q000098:blood supply* / Q000000981:diagnostic imaging; D001132:Arm / Q000098:blood supply* / Q000000981:diagnostic imaging; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*; D001795:Blood Pressure Determination; D005069:Evaluation Studies as Topic; D005263:Femoral Artery / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D011150:Popliteal Artery / Q000000981:diagnostic imaging; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011674:Pulse; D012008:Recurrence; D012039:Regional Blood Flow; D012680:Sensitivity and Specificity; D014463:Ultrasonography