title: Lead foreign body arthropathy in a horse.
abstract: A diagnosis of degenerative joint disease secondary to an intra-articular metallic foreign body in the right metacarpophalangeal joint was made in a Quarter Horse gelding. Arthroscopy, performed to evaluate the joint and remove the foreign body, revealed yellow discoloration of the articular cartilage and synovium, and blunting and proliferation of the synovium. The foreign body was identified as a lead sphere. Microscopic examination of synovium revealed chronic synovitis, with accumulation of hemosiderin and multifocal, mild mineralization. Another pigment was evident extracellularly in the synovium. Lead arthropathy was diagnosed. Lead arthropathy results from the dissolution of intra-articular lead, causing signs of chronic pain, restricted motion, joint effusion, and synovial proliferation.
authors: Texas Veterinary Medical Center, Department of Large Animal Medicine and Surgery, College Station.
authors: M R
authors: MR
authors: Crabill
authors: J P
authors: JP
authors: Watkins
authors: E L
authors: EL
authors: Morris
authors: R G
authors: RG
authors: Helman
authors: D G
authors: DG
authors: Schmitz
mesh_terms: D000818:Animals; D001182:Arthroscopy / Q000662:veterinary; D005547:Foreign Bodies / Q000150:complications / Q000601:surgery / Q000662:veterinary*; D006485:Hemosiderin / Q000032:analysis; D006734:Horse Diseases / Q000139:chemically induced / Q000209:etiology* / Q000601:surgery; D006736:Horses; D007794:Lameness, Animal / Q000139:chemically induced / Q000209:etiology; D007854:Lead; D007855:Lead Poisoning / Q000150:complications / Q000209:etiology / Q000662:veterinary; D008297:Male; D008663:Metacarpus; D010003:Osteoarthritis / Q000139:chemically induced / Q000209:etiology / Q000662:veterinary*; D013583:Synovial Membrane / Q000737:chemistry / Q000187:drug effects / Q000473:pathology
chemical_list: D007854:Lead; D006485:Hemosiderin