Case report: inhalation therapy of paromomycin is effective for respiratory infection and hypoxia by cryptosporidium with AIDS.
A 24-year-old man with AIDS and hemophilia A had intractable diarrhea and fever. Upon examination of stool and of a sigmoidal biopsy specimen, cryptosporidium was revealed. Approximately 2 months after admission, respiratory infection with hypoxia due to cryptosporidium developed. Paromomycin inhalation was effective therapy. To the authors' knowledge, this is the first case of respiratory cryptosporidiosis treated successfully by paromomycin inhalation.
Mohri
H
H
First Department of Internal Medicine, Yokohama City University School of Medicine, Japan.
Fujita
H
H
Asakura
Y
Y
Katoh
K
K
Okamoto
R
R
Tanabe
J
J
Harano
H
H
Noguchi
T
T
Inayama
Y
Y
Amano
T
T
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000280:Administration, Inhalation; D000328:Adult; D000818:Animals; D003457:Cryptosporidiosis / Q000188:drug therapy* / Q000209:etiology; D003458:Cryptosporidium; D006801:Humans; D000860:Hypoxia / Q000188:drug therapy / Q000209:etiology; D008174:Lung Diseases, Parasitic / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D010303:Paromomycin / Q000008:administration & dosage / Q000627:therapeutic use*
D010303:Paromomycin