title: Quantitative and qualitative fluctuation of water in the mouse submandibular gland under secretagogue effect.
abstract: The short-term effects of two different secretagogues on the water contained in the mouse submandibular gland were studied using the thermal analysis as investigation method. Isoproterenol induced a retention while pilocarpine promoted a release of weakly and strongly bound water. In addition, submandibular glands of subjects administered with isoproterenol were characterized by a thermal behaviour different in males and females above all as concerns the time of reaction to the secretagogue; the reaction delay observed in females was correlated with the effects of this pharmacological substance on the convoluted granular tubules that are responsible for the sexual dimorphism in mice.
authors: Dipartimento di Scienze Chimiche, Università La Sapienza, Roma, Italy.
authors: S
authors: S
authors: Materazzi
authors: R
authors: R
authors: Curini
authors: M G
authors: MG
authors: Gabrielli
authors: L
authors: L
authors: Fava
authors: G
authors: G
authors: Menghi
mesh_terms: D000818:Animals; D001834:Body Water / Q000378:metabolism*; D005260:Female; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010862:Pilocarpine / Q000494:pharmacology*; D012737:Sex Factors; D013363:Submandibular Gland / Q000187:drug effects / Q000502:physiology*; D013696:Temperature
chemical_list: D010862:Pilocarpine; D007545:Isoproterenol