title: Localization of the 9p melanoma susceptibility locus (MLM) to a 2-cM region between D9S736 and D9S171.
abstract: A familial melanoma susceptibility locus (MLM) was identified on the short arm of chromosome 9 in a set of Utah and Texas kindreds. Subsequent confirmation was reported for a set of 26 Australian kindreds, a set of 7 Dutch kindreds, and a set of 13 NIH melanoma kindreds. The original localization report placed the locus near the IFNA-D9S126 interval on chromosome 9p. We report further localization using D9S171 and a newly developed marker, D9S736, both of which lie in the IFNA-D9S126 interval. Analysis of this set of kindreds places the melanoma susceptibility locus in a 2-cM region that is proximal to D9S736 and distal to D9S171.
authors: Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City 84108.
authors: L A
authors: LA
authors: Cannon-Albright
authors: D E
authors: DE
authors: Goldgar
authors: S
authors: S
authors: Neuhausen
authors: N A
authors: NA
authors: Gruis
authors: D E
authors: DE
authors: Anderson
authors: C M
authors: CM
authors: Lewis
authors: M
authors: M
authors: Jost
authors: T D
authors: TD
authors: Tran
authors: K
authors: K
authors: Nyguen
authors: A
authors: A
authors: Kamb
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001315:Australia / Q000453:epidemiology; D002874:Chromosome Mapping; D002899:Chromosomes, Human, Pair 9; D005060:Europe / Q000208:ethnology; D005260:Female; D020022:Genetic Predisposition to Disease; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008126:Lod Score; D008297:Male; D008545:Melanoma / Q000453:epidemiology / Q000235:genetics*; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D010375:Pedigree; D013781:Texas / Q000453:epidemiology; D014589:Utah / Q000453:epidemiology