[Screening for deletion in patients with Duchenne's myodystrophy by multiplex amplification].
Patients with Duchenne muscular dystrophy were analyzed using the method of polymerase chain reaction in order to reveal deletions in the dystrophin gene. Deletions of different lengths and locations were detected in 28 of 78 ill boys. The highest number of deletions was detected in the 3'-end of the gene (the 45-50th exons).
Chukhrova
A L
AL
Malygina
N A
NA
Poliakov
A V
AV
Zaĭtseva
S P
SP
Sitnikov
V F
VF
Dadali
E L
EL
Kamennykh
L N
LN
Khrennikov
V Iu
VIu
Badalian
L O
LO
Evgrafov
O V
OV
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002872:Chromosome Deletion; D017931:DNA Primers; D016189:Dystrophin / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel; D005091:Exons / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009136:Muscular Dystrophies / Q000175:diagnosis / Q000235:genetics*; D016133:Polymerase Chain Reaction / Q000379:methods
D017931:DNA Primers; D016189:Dystrophin
Skrining deletsii u bol'nykh miodistrofieĭ Diushenna metodom mul'tipleksnoĭ amplifikatsii.