[Postoperative lavage. Experimental study of the use of antiseptic solutions].
The authors report their experience of surgical infections and particularly peritoneal intraoperative lavage. In a previous study they have standardized the technique. In this study they report on the lavage adding antiseptic substances in the solution. The experimental, controlled study, was carried out on Wistar rat stock, which were submitted to median laparotomy through which was injected a standard bacterial dose composed of 5 bn E. Coli. The peritoneal cavity was washed out after a few minutes with physiological solution with clorhexidine or PVPI dissolved. The main results were an increase of aderential syndrome and a less survival percent age (physiological solution = 100%, clorhexidine = 60%, iodophors = 23%). The authors concluded by pointing out that the use of antiseptic peritoneal lavage solution is a method that should be proscribed from operating rooms because it is unnecessary and detrimental to health.
Sortini
A
A
Istituto di Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi di Ferrara.
Sartori
A
A
Fabbri
N
N
Santini
M
M
Occhionorelli
S
S
Di Marco
L
L
Donini
I
I
D000818:Animals; D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D002710:Chlorhexidine / Q000009:adverse effects; D005260:Female; D007430:Intraoperative Care; D008297:Male; D010533:Peritoneal Lavage / Q000009:adverse effects*; D011205:Povidone / Q000009:adverse effects; D051381:Rats; D017208:Rats, Wistar; D012996:Solutions
D000891:Anti-Infective Agents, Local; D012996:Solutions; D011205:Povidone; D002710:Chlorhexidine
Il lavaggio postoperatorio. Studio sperimentale sull'uso di soluzioni antisettiche.