Endometrial polyps with predominant stromal component are characterized by a t(6;14)(p21;q24) translocation.
Cytogenetic investigation of endometrial polyps revealed the presence of a t(6;14)(p21;q24) as the sole abnormality in three cases. All tumors showed a histopathological pattern of predominant stromal hyperplasia with scarce representation of glandular elements, suggesting that a cytogenetic subgroup characterized by the t(6;14) translocation can be associated with endometrial polyps with a preponderant component of mesenchymal origin.
Vanni
R
R
Istituto di Biologia Generale, Cagliari (Sardinia), Italy.
Marras
S
S
Andria
M
M
Faa
G
G
D000328:Adult; D002883:Chromosomes, Human, Pair 14; D002896:Chromosomes, Human, Pair 6; D016889:Endometrial Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D011127:Polyps / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic