Pseudomyxoma peritonei: a report of eight cases.
OBJECTIVE
To assess the effectiveness of surgical treatment for pseudomyxoma peritonei.


METHODS
Retrospective analysis.


METHODS
Referral center.


METHODS
Eight patients with pseudomyxoma peritonei, five with mucinous tumors of the ovary and three with mucoceles of the appendix.


METHODS
All patients underwent cytoreductive surgery with removal of source i.e. panhysterectomy with appendicectomy in 5 and appendicectomy in 3. Systemic chemotherapy was used in 6 and systemic plus intraperitoneal chemotherapy in one case.


RESULTS
Over 18 to 86 months' follow up, two patients died (at 18 and 24 mo) and 2 are alive with recurrence. Recurrence occurred only in those with inadequate clearance of mucinous material at the initial operation. The remaining 4 patients are free of disease.


CONCLUSIONS
Aggressive surgical therapy with-chemotherapy is effective in providing long-term relief or cure in pseudomyxoma peritonei.
Sudhindran
S
S
Department of Gastroenterology, Deva Matha Hospital, Koothattukulam, Kerala.
Varghese
C J
CJ
Ramesh
H
H
D000328:Adult; D000368:Aged; D001062:Appendectomy; D001063:Appendiceal Neoplasms / Q000601:surgery*; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000601:surgery*; D011553:Pseudomyxoma Peritonei / Q000601:surgery*; D012189:Retrospective Studies