The clinical use of desflurane.
Desflurane, a newly introduced potent, inhaled anesthetic, differs from its predecessors in having a lower solubility in blood and tissues. The lower solubility imparts a greater control to the maintenance of anesthesia and a more rapid elimination and recovery from anesthesia. In other respects, the pharmacological properties of desflurane resemble those of its sister anesthetic, isoflurane, currently the most widely-used potent anesthetic in this and other countries. The qualitative exceptions to this resemblence are that desflurane is more pungent and produces a greater increase in heart rate, particularly at deeper levels of anesthesia.
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Department of Anesthesia, University of California, San Francisco 94143-0464.
D000769:Anesthesia, Inhalation; D000777:Anesthetics / Q000493:pharmacokinetics / Q000592:standards*; D000077335:Desflurane; D006801:Humans; D007530:Isoflurane / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000592:standards
D000777:Anesthetics; D000077335:Desflurane; D007530:Isoflurane