title: [Oligodeoxyribonucleotides containing 1-(beta-D-3'-deoxy-threo-pentofuranosyl)pyrimidine chains].
abstract: Effective methods of multiple incorporations of nucleotides with the inverted configuration of C2' hydroxyl group have been developed. The presence of tU and tC as 3'-terminal oligonucleotide modifications is shown to increase their resistance to snake venom phosphodiesterase. The obtained compounds are promising for the use in antisense biotechnology.
authors: T S
authors: TS
authors: Oretskaia
authors: Kh K
authors: KhK
authors: Ibragim
authors: E M
authors: EM
authors: Volkov
authors: E A
authors: EA
authors: Romanova
authors: V N
authors: VN
authors: Tashlitskiĭ
authors: Z A
authors: ZA
authors: Shabarova
mesh_terms: D001483:Base Sequence; D002851:Chromatography, High Pressure Liquid; D006868:Hydrolysis; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D011743:Pyrimidines / Q000032:analysis*
chemical_list: D009838:Oligodeoxyribonucleotides; D011743:Pyrimidines
vernacular_title: Oligodezoksiribonukleotidy, soderzhashchie 1-(beta-D-3'-dezoksi- treo-pentofuranozil)pirimidinovye zven'ia.