Preliminary results of HIV screening in sentinel facilities in Romania.
In the first months of 1994, 393 patients (random consecutive clinic attenders) from three sentinel clinics were tested for anti-V3 loop antibodies in ELISA with a branched synthetic peptide reproducing eight copies of full V3 sequence. Compared with a commercial HIV 1/2 ELISA kit the sensitivity of anti-V3 assay was 97.6% and the specificity 89.7%. The seroprevalence in women attending prenatal clinic was 7.54% and in children with multiple hospitalization record, 3.82%. Both heterosexual and parenteral transmission through unsafe medical practices fuel actual AIDS epidemic in Romania.
Cernescu
C
C
Stefan S. Nicolau Institute of Virology, Bucharest, Romania.
Popescu
A
A
Tîrdei
G
G
Alexandrescu
R
R
Ruţă
S M
SM
D000328:Adult; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015699:HIV Envelope Protein gp120 / Q000235:genetics; D006679:HIV Seropositivity / Q000175:diagnosis* / Q000453:epidemiology; D015528:HIV Seroprevalence; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D008969:Molecular Sequence Data; D012383:Romania / Q000453:epidemiology; D012680:Sensitivity and Specificity
D015483:HIV Antibodies; D015699:HIV Envelope Protein gp120