title: Hepatitis C virus infection in patients with non-Hodgkin's lymphoma.
abstract: Hepatitis C virus (HCV), which is both a hepatotropic and a lymphotropic virus, has been proposed as a possible causative agent of mixed cryoglobulinaemia. This 'benign' lymphoproliferative disorder can switch over to a malignant B-cell non-Hodgkin's lymphoma (NHL). Therefore HCV infection has been investigated in a series of 50 unselected Italian patients with B-cell NHL. Antibodies against HCV were found in 30% of NHL and HCV viraemia in 32% of cases. HCV-related markers were detected in 34% (17/50) of our NHL patients; this prevalence is particularly significant when compared with HCV seropositivity in Hodgkin's lymphoma (3%) and healthy controls (1.3%).
authors: Istituto Patologia Medica I, University of Pisa, Italy.
authors: C
authors: C
authors: Ferri
authors: F
authors: F
authors: Caracciolo
authors: A L
authors: AL
authors: Zignego
authors: L
authors: L
authors: La Civita
authors: M
authors: M
authors: Monti
authors: G
authors: G
authors: Longombardo
authors: F
authors: F
authors: Lombardini
authors: F
authors: F
authors: Greco
authors: E
authors: E
authors: Capochiani
authors: A
authors: A
authors: Mazzoni
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D016174:Hepacivirus / Q000302:isolation & purification; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000821:virology*; D008228:Lymphoma, Non-Hodgkin / Q000821:virology; D008297:Male; D008875:Middle Aged