General strategies and selection of derivatization reactions for liquid chromatography and capillary electrophoresis.
The general strategies, reasons and the different possibilities for the derivatization of biomedically important compounds are reviewed. Different approaches apply for small versus large analyte molecules, different advantages and disadvantages are visualized with pre- and post-column arrangements. Particular interest is focused upon solid-phase derivatization reagents.
Krull
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Department of Chemistry, Northeastern University, Boston, MA 02115.
Deyl
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Z
Lingeman
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D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004586:Electrophoresis / Q000379:methods*; D007202:Indicators and Reagents
D007202:Indicators and Reagents