Demonstration of antibodies against foot and mouth disease virus (FMDV) type O and Asia-1 in non-descriptive crossbred calves.
Sera from non-descriptive crossbred calves were screened for the presence of neutralizing antibodies against FMDV type O and Asia-1 for a period up to 215 days. The antibody titer of 16 remained constant up to 215 days against type O and up to 190 days against type Asia-1 virus in some animals. In majority of the animals the antibody titers remained constant up to three months. The possible reason for a frequent breakdown of immunity in the vaccinated animals even 3-4 months after vaccination could be the fact that the calves were vaccinated repeatedly at their very early age with an ill effect of immunization in the presence of persisting antibodies.
Sen
A K
AK
Indian Veterinary Research Institute, Hebbal, Bangalore.
Nair
S P
SP
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D005537:Aphthovirus / Q000276:immunology* / Q000302:isolation & purification*; D002417:Cattle / Q000821:virology; D002478:Cells, Cultured; D006224:Cricetinae; D004848:Epithelium; D009500:Neutralization Tests; D014059:Tongue
D000914:Antibodies, Viral