title: Preliminary results of HIV screening in sentinel facilities in Romania.
abstract: In the first months of 1994, 393 patients (random consecutive clinic attenders) from three sentinel clinics were tested for anti-V3 loop antibodies in ELISA with a branched synthetic peptide reproducing eight copies of full V3 sequence. Compared with a commercial HIV 1/2 ELISA kit the sensitivity of anti-V3 assay was 97.6% and the specificity 89.7%. The seroprevalence in women attending prenatal clinic was 7.54% and in children with multiple hospitalization record, 3.82%. Both heterosexual and parenteral transmission through unsafe medical practices fuel actual AIDS epidemic in Romania.
authors: Stefan S. Nicolau Institute of Virology, Bucharest, Romania.
authors: C
authors: C
authors: Cernescu
authors: A
authors: A
authors: Popescu
authors: G
authors: G
authors: Tîrdei
authors: R
authors: R
authors: Alexandrescu
authors: S M
authors: SM
authors: Ruţă
mesh_terms: D000328:Adult; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015699:HIV Envelope Protein gp120 / Q000235:genetics; D006679:HIV Seropositivity / Q000175:diagnosis* / Q000453:epidemiology; D015528:HIV Seroprevalence; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D008969:Molecular Sequence Data; D012383:Romania / Q000453:epidemiology; D012680:Sensitivity and Specificity
chemical_list: D015483:HIV Antibodies; D015699:HIV Envelope Protein gp120