Improved strategy for screening prospective blood donors for anaemia.
Women (568) and men (531) attending blood donation sessions in Wessex in September, 1992, were assessed for anaemia by the standard CuSO4 method on finger-prick (FP) blood samples. The haemoglobin (Hb) concentration on FP samples and on venous blood was also checked using the HemoCue. Different FP samples from the same donors revealed a wide variation on HemoCue. We recommend retaining the CuSO4 method on FP samples as the initial screen, and follow-up of apparent failures by determining the Hb concentration on venous sampling with the HemoCue. As 54% of females were found on venous samples to be below the current recommended threshold (125 g/L) for Hb concentration, we also recommend lowering the threshold to 115 g/L for women, and to 130 g/L for men. We further recommend a close re-examination of normal haematology values for adults.
Boulton
F E
FE
Wessex Regional Transfusion Centre, Southampton, U.K.
Nightingale
M J
MJ
Reynolds
W
W
D000740:Anemia / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D001782:Blood Donors; D001800:Blood Specimen Collection; D001815:Bloodletting; D011232:Chemical Precipitation; D003300:Copper; D019327:Copper Sulfate; D005069:Evaluation Studies as Topic; D005260:Female; D006452:Hemoglobinometry / Q000191:economics / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000191:economics / Q000295:instrumentation / Q000379:methods*; D010342:Patient Acceptance of Health Care; D010783:Photometry / Q000191:economics / Q000295:instrumentation; D015995:Prevalence; D012680:Sensitivity and Specificity
D003300:Copper; D019327:Copper Sulfate