[Genetic control of cellular differentiation and proliferation during gametogenesis in mammals].
Understanding the genetic program that controls the regulation of cells progressing through the mitotic and meiotic cell cycles, whether in response to growth factors, other extracellular signals, or intrinsic programs, is critical to problems in infertility and in gonadal neoplasias. In this study, we present a consideration of important stages of cell cycle control in mammalian germ cells and data illustrating the experimental approaches that can be used to determine the pattern of such genes which may be involved in these events.
Wolgemuth
D J
DJ
Department of Genetics and Development, Columbia University College of Physicians and Surgeons, NY, NY 10032.
Rhee
K
K
Ravnik
S E
SE
D000818:Animals; D002454:Cell Differentiation / Q000235:genetics*; D002455:Cell Division / Q000235:genetics*; D016213:Cyclins / Q000502:physiology; D005718:Gametogenesis / Q000235:genetics*; D015870:Gene Expression / Q000235:genetics; D005854:Germ Cells / Q000254:growth & development*; D006133:Growth Substances / Q000502:physiology; D051379:Mice; D008815:Mice, Inbred Strains
D016213:Cyclins; D006133:Growth Substances
Contrôle génétique de la différenciation et de la prolifération cellulaire pendant la gamétogénèse chez les mammifères.