title: Pathways of cysteine metabolism in MND/ALS.
abstract: Analysis of plasma from MND/ALS patients has shown no significant differences in metabolism of cysteine derivatives, although a sub-set of the population has raised glutamate values. Cysteine dioxygenase was found to have reduced activity in vitro, consistent with previous findings of a high plasma cysteine/sulphate ratio.
authors: School of Biochemistry, University of Birmingham, Edgbaston, UK.
authors: A
authors: A
authors: Pean
authors: G B
authors: GB
authors: Steventon
authors: R H
authors: RH
authors: Waring
authors: H
authors: H
authors: Foster
authors: S
authors: S
authors: Sturman
authors: A C
authors: AC
authors: Williams
mesh_terms: D000328:Adult; D000596:Amino Acids / Q000097:blood; D000690:Amyotrophic Lateral Sclerosis / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D003543:Cysteamine / Q000097:blood; D003545:Cysteine / Q000378:metabolism*; D050558:Cysteine Dioxygenase; D049308:Dioxygenases; D006801:Humans; D016472:Motor Neuron Disease / Q000378:metabolism*; D010105:Oxygenases / Q000378:metabolism; D011899:Ranitidine / Q000097:blood
chemical_list: D000596:Amino Acids; D003543:Cysteamine; D011899:Ranitidine; D010105:Oxygenases; D049308:Dioxygenases; D050558:Cysteine Dioxygenase; D003545:Cysteine