Pigmentary retinopathy with nephrotic syndrome, Ménétrier's disease, and diabetes mellitus.
A patient with pigmentary retinopathy, nephrotic syndrome, Ménétrier's disease, and diabetes mellitus is presented. Other complications were congestive heart failure, hypothyroidism, hypertension, and hypertriglyceridemia. Hypogenitalism was also suspected. Pigmentary retinopathy is known to associate with many systemic diseases, which are classified into several syndromes. This case superficially resembles Alström's disease due to the common characteristics of pigmentary retinopathy, diabetes mellitus, renal disease, and hypogenitalism. But clinically and histologically, there are distinct differences. To our knowledge, this association has never been reported.
Masugi
J
J
Second Department of Medicine, Kobe University School of Medicine.
Fukunaga
H
H
Ochi
F
F
Kimura
S
S
Akamatsu
T
T
Nakano
O
O
Sakamoto
T
T
Iwai
M
M
Amano
M
M
Fukuda
T
T
D003241:Consanguinity; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D005758:Gastritis, Hypertrophic / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000235:genetics* / Q000473:pathology; D012174:Retinitis Pigmentosa / Q000235:genetics*; D013270:Stomach / Q000473:pathology