Involuntary movement disorders associated with felbamate.
Two children developed involuntary movements while taking felbamate as an adjunct to their antiepileptic regimen. One exhibited choreoathetosis and the other an acute dystonic reaction. In both children the symptoms resolved with no recurrence after felbamate discontinuance.
Kerrick
J M
JM
Department of Pharmacy Practice, University of Minnesota, Minneapolis.
Kelley
B J
BJ
Maister
B H
BH
Graves
N M
NM
Leppik
I E
IE
D000293:Adolescent; D017668:Age of Onset; D017109:Akathisia, Drug-Induced / Q000503:physiopathology*; D000927:Anticonvulsants / Q000009:adverse effects* / Q000097:blood / Q000627:therapeutic use; D004569:Electroencephalography; D000078328:Felbamate; D006801:Humans; D007223:Infant; D008297:Male; D048448:Phenylcarbamates; D011409:Propylene Glycols / Q000009:adverse effects* / Q000097:blood / Q000493:pharmacokinetics; D012640:Seizures / Q000188:drug therapy* / Q000503:physiopathology
D000927:Anticonvulsants; D048448:Phenylcarbamates; D011409:Propylene Glycols; D000078328:Felbamate