title: Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines.
abstract: Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is distinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutralizing antibody response and was retained when the challenge virus was propagated in an unrelated cell line.
authors: Department of Veterinary Pathology, University of Glasgow, Bearsden, Scotland.
authors: M J
authors: MJ
authors: Hosie
authors: R
authors: R
authors: Osborne
authors: J K
authors: JK
authors: Yamamoto
authors: J C
authors: JC
authors: Neil
authors: O
authors: O
authors: Jarrett
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D002415:Cats; D016181:Feline Acquired Immunodeficiency Syndrome / Q000517:prevention & control*; D007114:Immunization; D016089:Immunodeficiency Virus, Feline / Q000276:immunology*; D015164:Vaccines, Inactivated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D015164:Vaccines, Inactivated; D014765:Viral Vaccines