Rhabdomyosarcoma and other soft tissue sarcomas of childhood.
The past year has seen the publication of several important findings regarding the epidemiology, molecular biology, and treatment of pediatric rhabdomyosarcoma and other childhood soft tissue sarcomas. These research advances will help us better understand the mechanisms involved in tumor development and progression, tailor therapy according to specific pretreatment tumor biologic characteristics, and develop novel treatments for rhabdomyosarcoma.
Pappo
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Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN 38101-0318.
D000293:Adolescent; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003952:Diagnostic Imaging; D004354:Drug Screening Assays, Antitumor; D005260:Female; D016161:Genes, Retinoblastoma; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D009381:Neoplasms, Radiation-Induced; D016609:Neoplasms, Second Primary; D015514:Oncogene Proteins, Fusion / Q000235:genetics; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000628:therapy; D014157:Transcription Factors / Q000235:genetics; D016896:Treatment Outcome; D014916:Whole-Body Irradiation
D015514:Oncogene Proteins, Fusion; D014157:Transcription Factors