title: Recovery of nocturnal melatonin concentration takes place within one week following cessation of 50 Hz circularly polarized magnetic field exposure for six weeks.
abstract: In our earlier paper [Kato et al. (1993): Bioelectromagnetics 14:97-106], melatonin concentration in pineal gland and blood was reported to be suppressed after exposure to a circularly polarized 50 Hz magnetic field for 6 weeks. In the present series of experiments, we investigated the time course of recovery after cessation of the exposure. Rats were exposed to a circularly polarized 50 Hz magnetic field at 1 microT for 6 weeks, and the melatonin concentration of blood of separate groups was determined at the end of the exposure and at 1 week and 4 weeks following cessation of exposure. Nocturnal melatonin concentration was reduced (P < 0.05) after 6 weeks of exposure. Melatonin concentration at 1 week following cessation of exposure was normal, and no further change was observed 4 weeks later.
authors: Department of Physiology, Hokkaido University School of Medicine, Sapporo, Japan.
authors: M
authors: M
authors: Kato
authors: K
authors: K
authors: Honma
authors: T
authors: T
authors: Shigemitsu
authors: Y
authors: Y
authors: Shiga
mesh_terms: D000818:Animals; D002940:Circadian Rhythm; D003624:Darkness; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure; D008297:Male; D008550:Melatonin / Q000032:analysis / Q000097:blood* / Q000528:radiation effects*; D010870:Pineal Gland / Q000737:chemistry / Q000528:radiation effects*; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D008550:Melatonin