[Renal transplantation in Bourneville tuberous sclerosis].
A 37 year-old patient with tuberous sclerosis and renal failure had renal transplantation performed, after 21 months of hemodialysis treatment and cerebral glioma removal, with good results 7 years later. In order to assess renal transplantation as a treatment for end-stage renal failure of tuberous sclerosis, we have reviewed the literature. 14 observations could be analysed: the patients were young with a mean age of 29.2 years, women in majority, with minor neurologic involvement. Because of the risks of neoplastic transformation and angiomyolipoma bleeding, bilateral nephrectomy is cautious, before or during the renal transplantation. Otherwise a close monitoring of the native kidneys by CT-scan is necessary. So the patients with tuberous sclerosis are good candidates for renal transplantation, with the same results as other patients of the same age, with no aggravation of the neurologic disorders, even when a cerebral tumor has been removed, as in our case.
Schillinger
F
F
Service de néphrologie hémodialyse, CH de Troyes.
Montagnac
R
R
D000328:Adult; D001932:Brain Neoplasms / Q000601:surgery; D005910:Glioma / Q000601:surgery; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D014402:Tuberous Sclerosis / Q000601:surgery*
Transplantation rénale dans la sclérose tubéreuse de Bourneville (STB).