Quantitation of alpha-1 proteinase inhibitor in the pulmonary epithelial lining fluid of horses with chronic obstructive pulmonary disease.
The concentration of alpha-1 proteinase inhibitor (API) was measured in the pulmonary epithelial lining fluid (PELF) of horses with chronic obstructive pulmonary disease (COPD) while they had clinical signs and while they had none. The concentrations of total protein, albumin and API were significantly higher in the PELF of animals with clinical signs of COPD. The correlation between albumin and API in the PELF suggested that most of the API was derived from the serum.
Milne
E M
EM
Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, Roslin, Midlothian.
Pemberton
A D
AD
McGorum
B C
BC
Dixon
P M
PM
Scudamore
C L
CL
Miller
H R
HR
D000818:Animals; D001992:Bronchoalveolar Lavage Fluid; D006734:Horse Diseases; D006736:Horses; D008173:Lung Diseases, Obstructive / Q000473:pathology / Q000662:veterinary*; D012016:Reference Values; D012709:Serum Albumin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis*
D012709:Serum Albumin; D000515:alpha 1-Antitrypsin