title: Hypothyroxinemia in acquired immune deficiency syndrome (AIDS).
abstract: Serum thyroxine (T4) and thyroid stimulating hormone (TSH) were studied in 38 patients confirmed to be infected with HIV-1 virus and the results compared with values observed in age matched healthy subjects. The mean serum total T4 in the majority of the patients, 103 +/- 32 nmol/L, was similar to values observed in the controls, 102 +/- 21 nmol/L, p > 0.05. However, 22.2 pc of the HIV-1 infected patients had total serum T4 values that were significantly lower than values in the controls, 36 +/- 12 nmol/L, p < 0.001. Since hypothyroxinemia has been associated with increased mortality in critical illness, we suggest that assessment of thyroid function may be helpful in the management of some patients with AIDS.
authors: Department of Radiation Medicine, University of Nigeria Teaching Hospital, Enugu.
authors: C C
authors: CC
authors: Ezeala
authors: E
authors: E
authors: Chukwurah
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006679:HIV Seropositivity / Q000150:complications*; D015497:HIV-1; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D008297:Male; D016555:Matched-Pair Analysis; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013972:Thyrotropin; D013974:Thyroxine