Prokaryotic translation: the interactive pathway leading to initiation.
Finding answers to the many open questions concerning the mechanism and control of prokaryotic translation remains one of the central challenges of molecular biology. In fact, recent experimental data even force us to reconsider aspects that were previously thought to be established fact. Here, we attempt a synthesis of new and not-so-new information, which leads to a revised and testable working hypothesis for translational initiation.
McCarthy
J E
JE
Department of Gene Expression, Gesellschaft Für Biotechnologische Forschung, Braunschweig, Germany.
Brimacombe
R
R
D001483:Base Sequence; D001665:Binding Sites; D004742:Enhancer Elements, Genetic; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D011387:Prokaryotic Cells; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000737:chemistry / Q000378:metabolism*; D012336:RNA, Ribosomal, 16S / Q000737:chemistry / Q000378:metabolism*
D012333:RNA, Messenger; D012336:RNA, Ribosomal, 16S