[Pharmacological studies on the effects of huanglian decoction on experimental gastric lesions in rats and antiemetic in pigeons].
The results showed that Huanglion decoction has protective effect on ethanol-,HCl- and aspirin-induced gastric hemorrhagic lesions in rats and antemetic effect on CuSO4-induced vomiting in pigeons. A dose of 27g/(kg.d) po applied in mice showed no toxic action. This dose is 400 times that of clinical application.
Qin
C L
CL
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.
Liu
J Y
JY
Cheng
Z M
ZM
D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use* / Q000633:toxicity; D000932:Antiemetics / Q000633:toxicity; D001241:Aspirin; D010856:Columbidae; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use* / Q000633:toxicity; D000431:Ethanol; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006851:Hydrochloric Acid; D008297:Male; D051379:Mice; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000139:chemically induced / Q000517:prevention & control*; D014839:Vomiting / Q000139:chemically induced / Q000517:prevention & control
D000897:Anti-Ulcer Agents; D000932:Antiemetics; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D000431:Ethanol; D006851:Hydrochloric Acid; D001241:Aspirin