title: Crystal structure of C-T-C-T-C-G-A-G-A-G. Implications for the structure of the Holliday junction.
abstract: The structure of the B-DNA decamer of sequence C-T-C-T-C-G-A-G-A-G shows a crossed arrangement of helices in the C2 crystal lattice. This is the fourth example of a crossed arrangement of B-DNA oligomers in a crystal, and in spite of the fact that each of these four crystallizes in a different lattice, all have nearly identical structures at the crossing contact. This ubiquitous crossing arrangement may be used to generate a structure for the Holliday junction that is fully consistent with the available physical data.
authors: Department of Chemistry and Biochemistry, University of California, Los Angeles 90024.
authors: D S
authors: DS
authors: Goodsell
authors: K
authors: K
authors: Grzeskowiak
authors: R E
authors: RE
authors: Dickerson
mesh_terms: D001483:Base Sequence; D002118:Calcium / Q000737:chemistry; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D011995:Recombination, Genetic
chemical_list: D009838:Oligodeoxyribonucleotides; D004247:DNA; D002118:Calcium