Translocation t(5;12)(q31-q33;p12-p13): a non-random translocation associated with a myeloid disorder with eosinophilia.
A t(5;12)(q33;p13) translocation has been detected in two patients with myeloid disorder and eosinophilia. Six other patients with haematological disease with eosinophilia with similar translocation have been published previously. The existence of a new entity, a myeloproliferative disorder with eosinophilia and t(5;12) (q31-q33;p12-p13), is suggested by the results of the present study.
Baranger
L
L
Laboratoire de Génétique, CHU Angers, France.
Szapiro
N
N
Gardais
J
J
Hillion
J
J
Derre
J
J
Francois
S
S
Blanchet
O
O
Boasson
M
M
Berger
R
R
D000368:Aged; D000369:Aged, 80 and over; D002881:Chromosomes, Human, Pair 12; D002895:Chromosomes, Human, Pair 5; D004802:Eosinophilia / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes; D009196:Myeloproliferative Disorders / Q000235:genetics*; D014178:Translocation, Genetic