Antioxidant activity of nitecapone and its analog OR-1246: effect of structural modification on antioxidant action.
Marcocci
L
L
Department of Molecular and Cell Biology, University of California at Berkeley 94720.
Suzuki
Y J
YJ
Tsuchiya
M
M
Packer
L
L
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002396:Catechols / Q000737:chemistry / Q000494:pharmacology*; D003574:Cytochrome c Group / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D016166:Free Radical Scavengers / Q000494:pharmacology*; D005609:Free Radicals; D007202:Indicators and Reagents; D007700:Kinetics; D008081:Liposomes; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction; D010422:Pentanones / Q000737:chemistry / Q000494:pharmacology*; D010545:Peroxides; D010713:Phosphatidylcholines; D051381:Rats; D012996:Solutions; D013050:Spectrometry, Fluorescence / Q000379:methods; D013053:Spectrophotometry / Q000379:methods; D013329:Structure-Activity Relationship; D013481:Superoxides; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis
D000975:Antioxidants; D002396:Catechols; D003574:Cytochrome c Group; D016166:Free Radical Scavengers; D005609:Free Radicals; D007202:Indicators and Reagents; D008081:Liposomes; D010422:Pentanones; D010545:Peroxides; D010713:Phosphatidylcholines; D012996:Solutions; D017392:Thiobarbituric Acid Reactive Substances; D013481:Superoxides; C088170:OR 1246; C049375:perhydroxyl radical; C057364:nitecapone; C017251:1,2-oleoylphosphatidylcholine