[Polyneuropathies and dysglobulinemias].
We review the concept fo Monoclonal Gammopathy emphasizing that the so called benign forms, with or without polyneuropathy can have an unpredictable evolution. Polyneuropathies associated to monoclonal gammopathy-IgM, IgG, IgA, Waldestrom's disease, Multiple myeloma, Osteosclerotic myeloma (POEMS), Amyloidosis and Cryoglobulinemias are reviewed. They generally are solely sensory, sensorimotor or rarely, solely motor. The importance of neuro-physiological studies and nerve biopsy is emphasized. For progressive forms, treatment with plasmapheresis, immunotherapy, corticoids or intravenous gammaglobulin is suggested.
Ferrer
S
S
Servicio de Neurología, Hospital Militar, Santiago de Chile.
Jiménez
C
C
D000368:Aged; D003449:Cryoglobulinemia / Q000150:complications / Q000276:immunology; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications* / Q000276:immunology; D011115:Polyneuropathies / Q000150:complications* / Q000276:immunology / Q000628:therapy; D011379:Prognosis
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Polineuropatiás y disglobulinemias.