[Effects of repeated sevoflurane anesthesia on hepatic and renal function in a pediatric patient].
A 10-yr-old boy with an injured lower extremity received sevoflurane anesthesia 5 times within 40 days. Laboratory tests for hepatic and renal function i.e., serum transaminase (glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, gamma-glutamyl transpeptidase), serum cholinesterase, plasma protein, serum cholinesterase, serum bilirubine, serum lactic dehydrogenase, serum prothrombin time, blood urea nitrogen, serum creatinine, beta 2-microglobulin, N-acetyl-D-glucosamidase and 24 hr-creatinine clearance remained within normal ranges throughout his perioperative period. Repeated sevoflurane anesthesia did not exert any adverse effect on hepatic and renal function in this patient.
Tanikawa
M
M
Department of Anesthesiology, Jichi Medical School, Tochigi.
Mitsuhata
H
H
Shimizu
R
R
Akazawa
S
S
Fukuda
H
H
Saitoh
K
K
Hirabayashi
Y
Y
Togashi
H
H
D000769:Anesthesia, Inhalation; D002648:Child; D004987:Ethers; D018409:Foot Injuries / Q000601:surgery; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007677:Kidney Function Tests; D008099:Liver / Q000503:physiopathology*; D008111:Liver Function Tests; D008297:Male; D008738:Methyl Ethers; D011184:Postoperative Period; D012086:Reoperation; D000077149:Sevoflurane
D004987:Ethers; D008738:Methyl Ethers; D000077149:Sevoflurane