Solitary eosinophilic granuloma of cerebral lobes. Value of immunohistochemistry for a diagnostic interpretation.
Primary cerebral eosinophilic granuloma is a very rare lesion. In this study we report a further observation of solitary fronto-parietal eosinophilic granuloma in a child of three years. The immunohistochemical pattern, with the strong positivity of the histiocytic cells for PG-M1, an antibody which does not stain the Langerhans cells, suggests the reactive nature of the granulomatous lesion.
Marafioti
T
T
Department of Human Pathology, University of Messina, Italy.
Cardia
E
E
D015703:Antigens, CD / Q000032:analysis; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D009419:Nerve Tissue Proteins / Q000032:analysis; D012640:Seizures / Q000209:etiology; D014057:Tomography, X-Ray Computed
D015703:Antigens, CD; D005904:Glial Fibrillary Acidic Protein; D009419:Nerve Tissue Proteins