Robb-Smith type malignant histiocytosis associated with a mediastinal germ cell tumor.
A 22-year-old Japanese man with a mediastinal germ cell tumor with mixed teratoma and hepatoid alpha-fetoprotein positive, and glandular yolk sac components, also demonstrated widely disseminated malignant histiocytosis involving the lungs, liver, pancreas, spleen, bone marrow and lymph nodes. Sensitivity to chemotherapy was acute and the patient died of disseminated intravascular coagulation syndrome within four months of his initial presentation.
Takahashi
S
S
First Department of Pathology, Nagoya City University Medical School.
Asamoto
M
M
Nakazawa
T
T
Kosaki
T
T
Katsumi
K
K
Shirai
T
T
D000328:Adult; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D018240:Endodermal Sinus Tumor / Q000473:pathology; D018237:Germinoma / Q000473:pathology*; D054747:Histiocytic Sarcoma / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology*; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology*