Use of low-osmolar agents and premedication to reduce the frequency of adverse reactions to radiographic contrast media: a survey of the Society of Uroradiology.
OBJECTIVE
To assess the decisions made by uroradiologists regarding choice of type of intravenous contrast material (low-osmolar contrast media [LOCM] vs conventional ionic agents) and frequency of use of corticosteroid prophylaxis.


METHODS
A questionnaire was mailed to 158 members of the Society of Uroradiology. There were 108 responses received, yielding a response rate of 68%. Results from 76 represented institutions were tabulated.


RESULTS
Most respondents practice at institutions in which LOCM are used selectively rather than universally. Corticosteroid prophylaxis in patients at risk is used with similar frequency at both types of institutions. There is considerable diversity in pretreatment regimens (ie, type and dose of corticosteroid used). Although antihistamines are used by many uroradiologists (almost always in conjunction with corticosteroids), H2 receptor antagonists are used at only a few institutions.


CONCLUSIONS
At institutions in which LOCM are used selectively, the majority of respondents use LOCM quite liberally, with most choosing these agents in patients at risk. Corticosteroid prophylaxis is widely used by respondents. There is much variation in the type of pretreatment regimen and its use in specific clinical settings.
Cohan
R H
RH
Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109-0030.
Ellis
J H
JH
Dunnick
N R
NR
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D003625:Data Collection; D004155:Diphenhydramine; D006634:Histamine H1 Antagonists / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D009994:Osmolar Concentration; D011292:Premedication; D014567:Urography
D000305:Adrenal Cortex Hormones; D003287:Contrast Media; D006634:Histamine H1 Antagonists; D004155:Diphenhydramine