[Home infusion chemotherapy in patients with relapsed or recurred stomach and colorectal cancer].
Five patients with distant metastasis from colorectal cancer who had good nutrition were treated with continuous intravenous administration of 5-FU infusion (400-450 mg/body/day) by infusor. The other five patients with advanced stomach cancer who could not have so good nutrition were receiving home parental nutrition (HPN, 1,200 kcal/day) and continuous or intermittent 5-FU infusion (250-500 mg/body/day) using Lentinan at the same time. In colorectal cancer, one partial response (PR) and one complete response (CR) were obtained. And in stomach cancer, only one NC were obtained but we could perform these HPN and chemotherapy for 13 months at home. According to our trial, we thought these chemotherapy and nutrition at home were useful to improve the quality of life of patients with GI tract cancer.
Sakuyama
T
T
Dept. of Surgery, Aoto Hospital, Jikei University, School of Medicine.
Takahashi
N
N
Nakamura
Y
Y
Shimono
S
S
Yamada
T
T
Takamura
S
S
Inomata
Y
Y
Isshi
K
K
Chibai
M
M
Tadaoka
N
N
D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D018575:Home Care Services, Hospital-Based; D018718:Home Infusion Therapy; D006801:Humans; D007262:Infusions, Intravenous; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D016331:Parenteral Nutrition, Home; D013274:Stomach Neoplasms / Q000473:pathology*
D005472:Fluorouracil