Eosinophilic gastroenteritis in a patient with large-cell anaplastic lung carcinoma: a paraneoplastic syndrome?
A 39-year-old man was hospitalized with abdominal pain and diarrhoea. The total eosinophil count was 11,800/dL; the jejunal biopsy showed diffuse and patchy eosinophils and plasma cell infiltration of the lamina propria; symptoms and hypereosinophilia disappeared after steroid therapy. Two months later the symptoms reappeared together with left supraclavicular lymphnode enlargement. The chest X-ray showed a mass within the left lung apex. Lymph node biopsy showed metastases from large-cell anaplastic carcinoma. The possibility of eosinophilic gastroenteritis as a paraneoplastic manifestation is discussed.
Stefanini
G F
GF
Istituto di Patologia Speciale Medica, Università degli Studi di Bologna, Italy.
Addolorato
G
G
Marsigli
L
L
Foschi
F G
FG
D'Errico
A
A
Scarani
P
P
Bonvicini
F
F
Bernardi
M
M
Gasbarrini
G
G
D000328:Adult; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications*; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications* / Q000188:drug therapy; D005759:Gastroenteritis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000188:drug therapy
D008775:Methylprednisolone