The ventilation, lactate and electromyographic thresholds during incremental exercise tests in normoxia, hypoxia and hyperoxia.
These experiments examined the effect of hypoxia and hyperoxia on ventilation, lactate concentration and electromyographic activity during an incremental exercise test in order to determine if coincident chances in ventilation and electromyographic activity occur during an incremental exercise test, despite an enhancement or reduction of peripheral chemoreceptor activity. In addition, these experiments were completed to determine if electromyographic activity and ventilation are enhanced or reduced in response to the inspiration of oxygen-depleted and oxygen-enriched air, respectively. Seven subjects performed three incremental exercise tests, until volitional exhaustion was achieved, while inspiring air with a fractional concentration of oxygen of either 66%, 21% or 17%. In addition, another single subject completed two tests while inspiring air with a fractional concentration of either 17% or 21%. During the tests, ventilation, mixed expired oxygen and carbon dioxide, arterialized venous blood and the electromyographic activity from the vastus lateralis were sampled. From these values ventilation, electromyographic and lactate thresholds were detected during normoxia, hypoxia and hyperoxia. The results showed that although ventilation and lactate concentration were significantly less during hyperoxia as compared to normoxia or hypoxia, the carbon dioxide production values were not significantly different between the normoxic, hypoxic and hyperoxic conditions. For a particular condition, the time, carbon dioxide production and oxygen consumption values that corresponded to the ventilation and electromyographic thresholds were not significantly different, but the values corresponding to the lactate threshold were significantly less than those for the electromyographic and ventilation thresholds. Comparisons between the three conditions showed that the time, carbon dioxide production and oxygen consumption values corresponding to each of these thresholds were not significantly difficult.(ABSTRACT TRUNCATED AT 250 WORDS)
Mateika
J H
JH
Department of Anesthesia, University of Toronto, Ontario, Canada.
Duffin
J
J
D000328:Adult; D015308:Anaerobic Threshold / Q000502:physiology; D001784:Blood Gas Analysis; D002245:Carbon Dioxide / Q000378:metabolism; D002628:Chemoreceptor Cells / Q000502:physiology; D004576:Electromyography; D005080:Exercise Test; D006801:Humans; D018496:Hyperoxia / Q000097:blood / Q000503:physiopathology*; D000860:Hypoxia / Q000097:blood / Q000503:physiopathology*; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D008297:Male; D009584:Nitrogen / Q000494:pharmacology; D010101:Oxygen Consumption / Q000502:physiology; D012119:Respiration / Q000502:physiology*
D007773:Lactates; D002245:Carbon Dioxide; D019344:Lactic Acid; D009584:Nitrogen