Alkylation of purine bases with 3,4-epoxy-1-butene, a reactive metabolite of 1,3-butadiene.
Neagu
I
I
Institute of Occupational Health, Finland.
Koivisto
P
P
Neagu
C
C
Kaltia
S
S
Kostiainen
R
R
Peltonen
K
K
D000225:Adenine / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D000478:Alkylation; D002070:Butadienes / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000032:analysis / Q000737:chemistry / Q000187:drug effects; D018736:DNA Adducts / Q000096:biosynthesis / Q000138:chemical synthesis; D004563:Electrochemistry; D004852:Epoxy Compounds / Q000737:chemistry / Q000378:metabolism*; D006147:Guanine / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D006361:Heating; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D009153:Mutagens / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism*; D011687:Purines / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism*; D012680:Sensitivity and Specificity
D002070:Butadienes; D018736:DNA Adducts; D004852:Epoxy Compounds; D009153:Mutagens; D011687:Purines; C024370:3,4-epoxy-1-butene; D006147:Guanine; D004247:DNA; D000225:Adenine; C031763:1,3-butadiene