title: Induction of c-fos-like protein in the spinoparabrachial tract-neurons locating within the sacral parasympathetic nucleus in the rat.
abstract: Immunoreactivity against c-fos-like protein (FOS) was induced in many neuronal cell bodies within the sacral parasympathetic nucleus (SPN) in urethane-anesthetized rats by chemical irritation of the urinary bladder with formalin. More than half of these FOS-immunoreactive neurons were retrogradely labeled with Fluoro-Gold injected into the lateral parabrachial nucleus (PBN1). The results indicate that some neurons within the SPN may transmit noxious information from the urinary bladder to the PBN1.
authors: Department of Anatomy, Fourth Military Medical University, Xi'an, People's Republic of China.
authors: Y Q
authors: YQ
authors: Ding
authors: B Z
authors: BZ
authors: Qin
authors: J S
authors: JS
authors: Li
authors: N
authors: N
authors: Mizuno
mesh_terms: D000818:Animals; D005260:Female; D005456:Fluorescent Dyes; D005557:Formaldehyde / Q000494:pharmacology; D007150:Immunohistochemistry; D008161:Lumbosacral Region; D009474:Neurons / Q000378:metabolism*; D010275:Parasympathetic Nervous System / Q000166:cytology / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism*; D011712:Pyramidal Tracts / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000166:cytology / Q000378:metabolism*; D013266:Stilbamidines; D001743:Urinary Bladder / Q000187:drug effects / Q000502:physiology
chemical_list: C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D005456:Fluorescent Dyes; D016760:Proto-Oncogene Proteins c-fos; D013266:Stilbamidines; D005557:Formaldehyde