title: Gourami lenses convert tryptophan into 3-hydroxykynurenine.
abstract: Although free tryptophan was found in the lens of both the kissing gourami (Helostoma temmincki) and the 3-spot gourami (Trichogaster trichopterus), only the lens of the latter species contained 3-hydroxykynurenine. Radiolabel experiments carried out on 3-spot gourami lenses in culture demonstrated that, as in humans, lenticular tryptophan is converted to 3-hydroxykynurenine probably via the intermediate kynurenine.
authors: Australian Cataract Research Foundation, University of Wollongong, NSW.
authors: R J
authors: RJ
authors: Truscott
authors: A M
authors: AM
authors: Wood
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005399:Fishes; D007737:Kynurenine / Q000031:analogs & derivatives* / Q000378:metabolism; D007908:Lens, Crystalline / Q000378:metabolism*; D009924:Organ Culture Techniques; D014364:Tryptophan / Q000378:metabolism*
chemical_list: C005045:3-hydroxykynurenine; D007737:Kynurenine; D014364:Tryptophan