title: Anaesthesia for caesarean section in a patient with Watson's syndrome.
abstract: Watson's syndrome is an uncommon genetic disorder whose features include mental retardation and pulmonary valvular stenosis. The purpose of this report is to describe one management strategy used successfully to anaesthetize a woman with this disorder who presented for Caesarean section. Epidural anaesthesia using 0.5% bupivacaine without epinephrine in 2-3 ml boluses to a total dose of 15 ml was administered over 30 min. Invasive haemodynamic monitoring in the form of arterial and central venous catheters were used to guide therapy and help ensure maternal and fetal well-being. Intravenous ketamine in doses of 10-20 mg every five minutes to a total dose of 245 mg (4.5 mg.kg-1) was used to overcome the patient's uncooperative nature and facilitate invasive procedures. Postoperative analgesia was provided using 3 mg epidural morphine. The patient was observed in the intensive care unit for the first postoperative day and experienced an uncomplicated intra- and postoperative course. We conclude that this technique represents a safe and effective method for anaesthetizing patients with this complicated problem for Caesarean section.
authors: Department of Anaesthesia, University of Ottawa, Ottawa Civic Hospital, Ontario.
authors: J B
authors: JB
authors: Conway
authors: M
authors: M
authors: Posner
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D002045:Bupivacaine / Q000008:administration & dosage; D002585:Cesarean Section; D016292:Procedural Sedation; D005260:Female; D005323:Fetal Monitoring; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D007649:Ketamine / Q000008:administration & dosage; D016343:Monitoring, Intraoperative; D009020:Morphine / Q000008:administration & dosage; D011247:Pregnancy; D011666:Pulmonary Valve Stenosis / Q000235:genetics*; D013577:Syndrome
chemical_list: D007649:Ketamine; D009020:Morphine; D002045:Bupivacaine