title: Assessment of inhomogeneities in elastic properties of in situ and reversed saphenous vein grafts in humans.
abstract: The elastic properties of newly implanted in situ (IS, n = 11) and reversed (RV, n = 21) saphenous grafts were studied with the use of Vessel Wall Doppler Tracking. From diameter, diameter change and simultaneously recorded pulse pressure, distensibility coefficient (DC) representing the intrinsic elastic properties and compliance coefficient (CC), a parameter of haemodynamic capacity, were calculated. In order to obtain a mechanical profile, the parameters were assessed at defined sites down the graft and native arterial system. In the RV group the reversal of the grafts resulted in a difference in diameter around the proximal anastomoses (7.4 vs. 4.3 mm, p < 0.01) and from proximal to distal (4.3 vs. 5.9 mm, p < 0.01) in the grafts; around the distal anastomoses no differences in diameter were observed. Due to the natural taper of the in situ grafts, diameter decreased from proximal to distal in the grafts (4.5 vs. 3.2 mm, p < 0.05) and no size differences were found around the anastomoses. In the RV group a decrease in DC was observed from proximal to distal in the grafts; whereas in the IS group no change in DC was found from proximal to distal in the grafts but a decrease in DC was observed around the distal anastomoses. In the RV group, a decrease in CC at the proximal anastomoses was observed (0.25 vs. 0.09 mm2/kPa, p < 0.01). In the IS group no change in CC was observed around the proximal anastomoses and distal anastomoses.(ABSTRACT TRUNCATED AT 250 WORDS)
authors: Department of Surgery, Univeristy Hospital of Maastricht, The Netherlands.
authors: L
authors: L
authors: Hofstra
authors: D C
authors: DC
authors: Bergmans
authors: A P
authors: AP
authors: Hoeks
authors: J H
authors: JH
authors: Tordoir
authors: P J
authors: PJ
authors: Kitslaar
mesh_terms: D000368:Aged; D001166:Arteriovenous Shunt, Surgical; D004548:Elasticity; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D007383:Intermittent Claudication / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D011150:Popliteal Artery / Q000601:surgery*; D012501:Saphenous Vein / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000637:transplantation*; D014182:Transplantation, Autologous; D018608:Ultrasonography, Doppler; D014654:Vascular Patency / Q000502:physiology