Development, critical period plasticity, and adult reorganizations of mammalian somatosensory systems.
This review covers recent progress in three major areas of investigation in somatosensory systems: development, developmental plasticity and functional reorganization. Important findings relate to the development of periphery-related patterning in thalamic afferents to somatosensory cortex, the controversial role of neural activity in the development and plasticity of periphery-related afferent patterning in the brainstem and cortex, experience-dependent reorganizations in adult somatosensory cortex, and the locus of these changes.
O'Leary
D D
DD
Molecular Neurobiology Laboratory, Salk Institute, La Jolla, California 92037.
Ruff
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NL
Dyck
R H
RH
D000818:Animals; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology*; D013003:Somatosensory Cortex / Q000254:growth & development* / Q000502:physiology; D013788:Thalamus / Q000254:growth & development / Q000502:physiology; D014276:Trigeminal Nerve / Q000254:growth & development / Q000502:physiology