title: Paraneoplastic cerebellar disorders.
abstract: Paraneoplastic cerebellar degeneration typically begins with rapidly progressive ataxia of the trunk and extremities. Antineuronal antibodies are found in about half the patients. The most specific autoantibody is an anti-Purkinje cell antibody found in women with gynecologic tumors. Even after the tumor is removed, the cerebellar deficit persists in most patients.
authors: Department of Neurology, University of California, Los Angeles School of Medicine.
authors: R W
authors: RW
authors: Baloh
mesh_terms: D001323:Autoantibodies / Q000032:analysis; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009474:Neurons / Q000276:immunology; D015835:Ocular Motility Disorders / Q000209:etiology; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology* / Q000628:therapy; D015837:Vestibular Diseases / Q000209:etiology
chemical_list: D001323:Autoantibodies