title: Upper airway carriage by Haemophilus influenzae and Streptococcus pneumoniae in Australian aboriginal children hospitalised with acute lower respiratory infection.
abstract: When nasopharyngeal secretions from 171 Australian Aboriginal children hospitalized with acute lower respiratory tract infections (ALRI) were cultured selectively for Streptococcus pneumoniae and Haemophilus influenzae, 136 (79.5%) and 151 (88.3%) children yielded 166 and 254 isolates of S. pneumoniae and H. influenzae, respectively. In colonized subjects multiple populations of S. pneumoniae (20% of carriage-positive patients) and H. influenzae (55%) were common. Pneumococci belonging to 27 types or groups were identified. H. influenzae serotype b colonized 16.4% of all children studied. More than one half of 152 children tested were excreting antibiotics at the time of admission to hospital. Significantly fewer children with serum antibiotic residues were colonized with S. pneumoniae than were antibiotic free children. Antibiotic usage had no measurable impact on the isolation rate of H. influenzae.
authors: Acute Respiratory Infections Research Laboratory, Queensland Institute of Medical Research, Herston, Brisbane.
authors: M
authors: M
authors: Gratten
authors: K
authors: K
authors: Manning
authors: J
authors: J
authors: Dixon
authors: F
authors: F
authors: Morey
authors: P
authors: P
authors: Torzillo
authors: J
authors: J
authors: Hanna
authors: J
authors: J
authors: Erlich
authors: V
authors: V
authors: Asche
authors: I
authors: I
authors: Riley
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000097:blood / Q000627:therapeutic use; D002353:Carrier State / Q000097:blood / Q000188:drug therapy / Q000208:ethnology* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D016903:Drug Monitoring; D004350:Drug Residues; D004363:Drug Utilization; D005260:Female; D006192:Haemophilus Infections / Q000097:blood / Q000188:drug therapy / Q000208:ethnology* / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017053:Infection Control; D008297:Male; D009305:Nasopharynx / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000097:blood / Q000188:drug therapy / Q000208:ethnology* / Q000382:microbiology*; D044469:Racial Groups; D012141:Respiratory Tract Infections / Q000097:blood / Q000188:drug therapy / Q000208:ethnology* / Q000382:microbiology*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification
chemical_list: D000900:Anti-Bacterial Agents