Comparison of single- and dual-energy quantitative computed tomography for therapy control under antiosteoporotic treatment.
Lumbar spine bone mineral density was determined in 50 female patients (mean age: 55.4 +/- 12.3 years), who were treated because of osteoporosis or osteopenia. Bone mineral density was assessed using single-energy QCT with 80 and 120 kV tube voltage and with dual-energy QCT. Compared to single-energy QCT, dual-energy QCT showed much higher variability of the bone density values obtained. Therefore we conclude that single energy QCT is a method that allows precise and reproducible determination of spinal bone mineral content under clinical conditions which cannot be further improved by the use of dual-energy QCT.
Pfeifer
T
T
Department of Diagnostic Radiology, University of Ulm, Germany.
Ulrich
U
U
Knöferl
M W
MW
D000328:Adult; D000368:Aged; D015519:Bone Density / Q000502:physiology*; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging / Q000628:therapy; D002138:Calibration; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D008875:Middle Aged; D010024:Osteoporosis / Q000000981:diagnostic imaging* / Q000628:therapy; D014057:Tomography, X-Ray Computed / Q000379:methods*