Formation of thymidine, cyclic deoxyguanosine and cyclic deoxycytidine adducts of the mutagen 2-bromoacrolein and their role in mutagenicity and clastogenicity.
Meerman
J H
JH
University of Leiden, Division of Toxicology, The Netherlands.
van Beerendonk
G J
GJ
Nelson
S D
SD
D000171:Acrolein / Q000031:analogs & derivatives* / Q000378:metabolism / Q000633:toxicity; D000818:Animals; D018736:DNA Adducts / Q000096:biosynthesis*; D004277:DNA, Single-Stranded / Q000187:drug effects / Q000378:metabolism; D003841:Deoxycytidine / Q000378:metabolism*; D003849:Deoxyguanosine / Q000378:metabolism*; D009153:Mutagens / Q000378:metabolism* / Q000633:toxicity*; D051381:Rats; D013936:Thymidine / Q000378:metabolism*
D018736:DNA Adducts; D004277:DNA, Single-Stranded; D009153:Mutagens; D003841:Deoxycytidine; C041548:2-bromoacrolein; D000171:Acrolein; D003849:Deoxyguanosine; D013936:Thymidine