title: [Mechanism of disorders of the cerebral blood supply during stress in spontaneously hypertensive rats].
abstract: The immobilization- and sound stimulus-induced changes in cerebral circulation were studied in spontaneously hypertensive rats. It was found that there was a stress-induced increase in the levels of epinephrine and norepinephrine in brain tissue, which was associated with lower levels of vasoactive prostaglandins E and F2 and with their imbalance with vasodilator prostaglandins E being prevalent. The change in the cerebral ratio of biologically active substances results in cerebral blood flow autoregulation failure and development of large cerebral hemorrhages.
authors: T P
authors: TP
authors: Romanova
authors: G G
authors: GG
authors: Karpel'
authors: G E
authors: GE
authors: Brill'
authors: Kh M
authors: KhM
authors: Markov
mesh_terms: D000818:Animals; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000503:physiopathology*; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008297:Male; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D013312:Stress, Physiological / Q000150:complications / Q000503:physiopathology*
vernacular_title: K mekhanizmu narusheniia krovosnabzheniia golovnogo mozga pri stresse u spontanno gipertenzivnykh krys.