[Exclusion of alpha-linolenic acid from diets for rats during several generations. I. Effect on reproduction and postnatal growth].
The effects of a dietary alphalinolenic acid (18: 3w3) deficiency on reproduction and post natal growth in rats during 3 successive generations were studied. Female rats received respectively a diet with sunflower oil at 10% (deficient diet) or a diet with soya oil at 10% (control diet). The results showed that in our experimental conditions deficient diet affects: fecundity, fertility, post natal growth and cause a high rates of perinatal mortality from birth to post partum day 3: Perinatal mortality increased with successive gestation from 14.6% to 18.6% compared with the survival of control. The fatty acid composition of placenta phospholipids and milk lipids reflected the nature of the dietary oil. The possibility that 18: 3w3 might function in a way different from the EFA role of 18: 2w6 in reproduction at least in rats has been discussed.
Araya
J
J
Departamento de Nutrición, Facultad de Medicina, Universidad de Chile.
Cagalj
A
A
D000818:Animals; D004032:Diet; D005260:Female; D006128:Growth; D008297:Male; D008892:Milk / Q000737:chemistry; D010920:Placenta / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D012098:Reproduction; D017962:alpha-Linolenic Acid / Q000008:administration & dosage* / Q000032:analysis; D017965:gamma-Linolenic Acid / Q000008:administration & dosage / Q000032:analysis
D017962:alpha-Linolenic Acid; D017965:gamma-Linolenic Acid
Exclusión del ácido alfalinolénico de la dieta de la rata durante varias generaciones. I. Efecto en la reproducción y crecimiento postnatal.