Correlation of DNA flow cytometry and hormone receptors with axillary lymph node status in patients with carcinoma of the breast.
Axillary lymph node dissection (ALND) remains a standard staging procedure for patients with primary carcinoma of the breast. In a retrospective review of 63 patients with primary breast cancer who underwent ALND, statistical analysis showed that only tumor size was correlated with axillary lymph node involvement. Neither hormone receptor status, ploidy, nor percent S-phase contributed more to prediction of nodal size. Statistical analysis also indicated a significant correlation between receptor-negative status and the presence of positive axillary lymph nodes.
Friedman
N S
NS
Sinai Hospital of Baltimore, MD.
Freedman
M D
MD
D001365:Axilla; D001943:Breast Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011003:Ploidies; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D012307:Risk Factors
D004273:DNA, Neoplasm; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone