Influence of vagal afferents in the sneeze reflex in cats.
We studied the effects of bilateral vagotomy and step pulmonary inflations (5, 10, 15 mmHg, i.e., 0.66, 1.33, 2 kKPa) on sneeze reflex in ketamine-anaesthetized cats. Bilateral vagotomy lengthens the duration of preparatory inspiration and diminishes the amplitude of expiratory activities in sneeze. In contrast, 5 mmHg pulmonary inflation facilitates the sneeze. It shortens the inspiratory preparation and increases the frequency of sneeze attacks. At 10 mmHg pulmonary inflations, inspiration is inhibited and only expiratory thrust occurs. At 15 mmHg pulmonary inflations, vagal afferent stimulations inhibit the sneeze.
Macron
J M
JM
Laboratoire de Neurophysiologie, CNRS URA 1331, Faculté de Médecine, Université de Picardie, Amiens, France.
Wallois
F
F
Duron
B
B
D000344:Afferent Pathways; D000818:Animals; D002415:Cats; D008176:Lung Volume Measurements; D009297:Nasal Mucosa / Q000502:physiology; D009475:Neurons, Afferent / Q000502:physiology*; D010812:Physical Stimulation; D011312:Pressure; D012018:Reflex / Q000502:physiology*; D015656:Respiratory Mechanics; D012912:Sneezing / Q000502:physiology*; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology*