Effects of lamprey gonadotropin-releasing hormone-III on steroidogenesis and spermiation in male sea lampreys.
The biological activities of lamprey gonadotropin-releasing hormone-III (GnRH-III) were determined in the adult male sea lamprey, Petromyzon marinus. One injection of lamprey GnRH-III at 0.1 or 0.2 microgram/g body wt stimulated plasma estradiol and progesterone levels in adult male sea lampreys undergoing final maturation. Four successive injections of lamprey GnRH-III at 0.1 microgram/g of lamprey GnRH-1 at 0.2 microgram/g induced spermiation in 78 or 30% of the lampreys, respectively, compared to 0% in controls by Day 16. In summary, lamprey GnRH-III is biologically active in stimulating the pituitary-gonadal axis in adult male lampreys.
Deragon
K L
KL
Department of Biochemistry and Molecular Biology, University of New Hampshire, Durham 03824.
Sower
S A
SA
D000818:Animals; D004958:Estradiol / Q000097:blood / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007798:Lampreys / Q000378:metabolism*; D008297:Male; D010902:Pituitary Gland / Q000502:physiology; D011374:Progesterone / Q000097:blood / Q000378:metabolism*; D013083:Sperm Transport / Q000187:drug effects*; D013737:Testis / Q000502:physiology
D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone; D004958:Estradiol