title: Simulation of marker assisted selection for non-additive traits.
abstract: Marker Assisted Selection (MAS) based on additive effects associated with alleles at marker loci, estimated by linear regression of individual phenotype on the markers, was applied to characters with non-additive gene action and non-additive environment. The base population was the F2 generation of a cross between two inbred lines. Computer simulations of MAS were conducted for characters with dominance, epistasis and genotype-environment interaction approximated by the 'additive-multiplicative' model. MAS was more effective than purely phenotypic selection in all cases. The efficiency of MAS for characters with non-additive gene action is comparable to (and for negative dominance even higher than) the efficiency of MAS for strictly additive characters. Environmental non-additivity, however, lowers the efficiency of MAS. Almost all results concerning the efficiency of MAS in our previous simulations of purely additive traits are applicable to non-additive traits.
authors: Department of Biology, University of Oregon, Eugene 97403.
authors: A
authors: A
authors: Gimelfarb
authors: R
authors: R
authors: Lande
mesh_terms: D000818:Animals; D003198:Computer Simulation; D004843:Epistasis, Genetic; D005260:Female; D005799:Genes, Dominant; D008040:Genetic Linkage; D005819:Genetic Markers; D016014:Linear Models; D008297:Male; D008957:Models, Genetic; D010641:Phenotype; D012641:Selection, Genetic
chemical_list: D005819:Genetic Markers