Further studies on new furostanol saponins from the bulbs of Allium macrostemon.
Further studies by means of preparative HPLC led to the isolation of two new furostanol saponins, macrostemonoside J (1) and L (3), along with an artifact, macrostemonoside K (2) from the bulbs of Allium macrostemon. On the basis of chemical evidence and spectral analysis (1H-, 13C-NMR and FAB-MS), the structure of 1 was elucidated to be 26-O-beta-D-glucopyranosyl 2 beta,3 beta,22,26-tetrahydroxy-25(R)-5 beta-furostan 3-O-beta-D-glucopyranosyl (1-->2)-beta-D-galactopyranoside. 3 was deduced to be 26-O-beta-D-glucopyranosyl 2 beta,3 beta,26-trihydroxy-25(R)-5 beta-furostan- 20(22)-ene 3-O-beta-D-glucopyranosyl (1-->2)-beta-D-galactopyranoside.
Peng
J
J
Department of Pharmacology of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang.
Yao
X
X
Okada
Y
Y
Okuyama
T
T
D000490:Allium / Q000737:chemistry*; D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013329:Structure-Activity Relationship
D010936:Plant Extracts; D012503:Saponins