title: The fibulin-1 gene (FBLN1) is located on human chromosome 22 and on mouse chromosome 15.
abstract: Fibulin-1 is a calcium-binding glycoprotein present in the extracellular matrix and in the serum. The gene coding for fibulin-1 (FBLN1) was located by in situ hybridization of 3H-labeled cDNA probes to human and mouse metaphase chromosomes. The gene was assigned to the q13.2-q13.3 region of human chromosome 22 and to the E-F band of mouse chromosome 15. This finding extends the evolutionary conservation between human chromosome 22 and mouse chromosome 15.
authors: U-242 INSERM, Hôpital d'Enfants de la Timone, Marseille, France.
authors: M G
authors: MG
authors: Mattei
authors: T C
authors: TC
authors: Pan
authors: R Z
authors: RZ
authors: Zhang
authors: R
authors: R
authors: Timpl
authors: M L
authors: ML
authors: Chu
mesh_terms: D000818:Animals; D002135:Calcium-Binding Proteins / Q000235:genetics*; D002478:Cells, Cultured; D002874:Chromosome Mapping; D002892:Chromosomes, Human, Pair 22; D005796:Genes; D006801:Humans; D017403:In Situ Hybridization; D008214:Lymphocytes / Q000648:ultrastructure; D051379:Mice / Q000235:genetics*; D009363:Neoplasm Proteins / Q000235:genetics*
chemical_list: D002135:Calcium-Binding Proteins; D009363:Neoplasm Proteins; C060820:fibulin