[Quantitative analysis of synephrine in zhishi injection by RP-HPLC].
A reversed phase HPLC method was developed for the determination of synephrine in Zhishi Injection using methanol-water (1:1) containing sodium 1-pentane sulfonate (3.5%, G/V) and acetic acid (0.1%, V/V) as the mobile phase with UV detoction at 275nm. Linear response was obtained in the range of 8-64 micrograms/ml (r = 0.9998), the absolute recovery was 96.2-103.4%, and RSD 2.7%-6.0% (n = 7).
Xiang
D X
DX
Second Affiliated Hospital of Hunan Medical University, Zhangsha.
Zhao
X Y
XY
Chen
X Z
XZ
Tan
Z R
ZR
Xie
W B
WB
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000592:standards; D011786:Quality Control; D013578:Synephrine / Q000032:analysis*
D004365:Drugs, Chinese Herbal; D013578:Synephrine