title: Phylogenetic analysis of the rpoB gene from the plastid-like DNA of Plasmodium falciparum.
abstract: Malaria and other Apicomplexan parasites harbour two extrachromosomal DNAs. One is mitochondrial and the other is a 35-kb circle with some plastid-like features but whose provenance and function is unknown. In addition to genes for rRNAs, tRNAs and ribosomal proteins, the 35-kb circular DNA of Plasmodium falciparum carries an rpoBC operon which encodes subunits of a eubacteria-like RNA polymerase. The phylogenetic analysis of the complete rpoB sequence presented here supports our inference that the 35-kb circle is the remnant of a plastid genome.
authors: Parasitology Division, National Institute for Medical Research, Mill Hill, London, UK.
authors: M J
authors: MJ
authors: Gardner
authors: N
authors: N
authors: Goldman
authors: P
authors: P
authors: Barnett
authors: P W
authors: PW
authors: Moore
authors: K
authors: K
authors: Rangachari
authors: M
authors: M
authors: Strath
authors: A
authors: A
authors: Whyte
authors: D H
authors: DH
authors: Williamson
authors: R J
authors: RJ
authors: Wilson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003062:Codon / Q000235:genetics; D017931:DNA Primers / Q000235:genetics; D004270:DNA, Circular / Q000235:genetics; D016054:DNA, Protozoan / Q000235:genetics*; D012321:DNA-Directed RNA Polymerases / Q000235:genetics; D005111:Extrachromosomal Inheritance; D017125:Genes, Protozoan; D008969:Molecular Sequence Data; D010802:Phylogeny; D010963:Plasmodium falciparum / Q000201:enzymology / Q000235:genetics*; D018087:Plastids / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity
chemical_list: D003062:Codon; D017931:DNA Primers; D004270:DNA, Circular; D016054:DNA, Protozoan; D012321:DNA-Directed RNA Polymerases