title: Biochemical analysis of tunica vaginalis fluid in patients with or without idiopathic hydroceles.
abstract: OBJECTIVE
  To establish the differences, if any, between the biochemical composition of idiopathic hydrocele fluid and the fluid normally present in the tunica vaginalis.
  
  
  METHODS
  Aspiration and sclerotherapy of 37 idiopathic hydroceles from patients who presented to this urology clinic were performed. The biochemical content of the fluid was compared with that of the tunica vaginalis fluid from a small group of controls (n = 8), taken from patients undergoing orchidectomy for carcinoma of the prostate.
  
  
  RESULTS
  Differences in several measurements were recorded; in particular, there were significantly higher concentrations of calcium, albumin, total protein and creatine-kinase in the hydrocele group. The levels of potassium, aspartate transaminase, alanine transaminase and alkaline phosphatase were significantly lower in the hydrocele group.
  
  
  CONCLUSIONS
  Whether these differences have a role in the causation of an idiopathic hydrocele is, at this stage, speculative. A similar study on a larger scale would probably be more conclusive.
authors: Department of Urology, Medical University of Southern Africa, Medunsa.
authors: T S
authors: TS
authors: Madlala
authors: R K
authors: RK
authors: Rencken
authors: M S
authors: MS
authors: Bornman
authors: S
authors: S
authors: Reif
authors: H F
authors: HF
authors: Joubert
authors: C A
authors: CA
authors: Van der Merwe
mesh_terms: D000418:Albumins / Q000032:analysis; D000469:Alkaline Phosphatase / Q000032:analysis; D002118:Calcium / Q000032:analysis; D002784:Cholesterol / Q000032:analysis; D003402:Creatine Kinase / Q000032:analysis; D005122:Exudates and Transudates / Q000378:metabolism; D006801:Humans; D008297:Male; D011188:Potassium / Q000032:analysis; D011506:Proteins / Q000032:analysis; D006848:Testicular Hydrocele / Q000378:metabolism*; D013737:Testis / Q000737:chemistry*; D000637:Transaminases / Q000032:analysis
chemical_list: D000418:Albumins; D011506:Proteins; D002784:Cholesterol; D000637:Transaminases; D003402:Creatine Kinase; D000469:Alkaline Phosphatase; D011188:Potassium; D002118:Calcium