Prevalence of HIV infections among patients attending a Parisian anonymous testing center between 1988 and 1993.
The prevalence of HIV infection was assessed among 15,611 consecutive patients attending a Parisian anonymous testing center from April 1988 to June 1993. Sera (17,910) were tested for the presence of anti-HIV antibodies using two different enzyme-linked immunosorbent assays. Seropositivity was verified by Western blotting. The sera were also assayed for HIV antigenemia detection in 2,493 cases. Six hundred and seventy-seven patients were found to be anti-HIV antibody positive: among them 666 were infected by HIV-1 and only 11 by HIV-2. Antigenemia was detected in 108 samples (4.3%). In all cases but 5, antigenemia was associated with the presence of specific antibodies. Risk factors for HIV infection could be determined for 5,735 patients. The HIV prevalence rates were 5.2% in 1988-89, 4.9% in 1990, 3.4% in 1991, 2.8% in 1992 and 1.8% for the 6 first months of 1993 (p < 0.01). Only one patient was coinfected with HTLV-1. This study shows a trend of decreasing seropositivity rates among the patients attending the anonymous testing center since 1990. By contrast, the percentage of seropositive patients with antigenemia was stable between 1988 and 1993.
Mazeron
M C
MC
Service de Bactériologie-Virologie, Hôpital Lariboisière, Université Paris VII, France.
Cervoni
J
J
Alain
S
S
Honderlick
P
P
Raskine
L
L
Chassany
O
O
Caulin
C
C
Sanson-Le Pors
M J
MJ
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology* / Q000276:immunology; D005602:France / Q000453:epidemiology; D015483:HIV Antibodies / Q000032:analysis*; D015481:HTLV-I Antibodies / Q000032:analysis*; D015482:HTLV-II Antibodies / Q000032:analysis*; D006801:Humans; D015995:Prevalence
D015483:HIV Antibodies; D015481:HTLV-I Antibodies; D015482:HTLV-II Antibodies