Ornithine decarboxylase, fatty acid synthetase, and lipid levels in selected organs of the postnatal developing male miniature pig.
Ornithine decarboxylase (ODC) and fatty acid synthetase (FAS) activities were determined in tissues from male neonate and juvenile miniature swine (Hormel-Hanford strain) at various ages. ODC activity was measured in liver, brain, kidney, pancreas, and spleen at one day and at 1, 4, 8, 12 and between 24 and 32 weeks. Hepatic FAS activity, total lipid, triglyceride, and total cholesterol were measured at 2, 8, 16, and 32 weeks. Generally, tissue ODC activity was highest in the spleen at all ages. Three postnatal patterns of ODC activity were observed for the different organs. The mean values of FAS activity, total lipid, and cholesterol were highest at 8 weeks compared to other sampling periods.
Gaines
D W
DW
Food and Drug Administration, Center for Food Safety and Applied Nutrition, Laurel, Maryland 20708.
Friedman
L
L
Newell
R F
RF
Matthews
R N
RN
Sager
A O
AO
Braunberg
R C
RC
Henderson
G R
GR
D000818:Animals; D001835:Body Weight; D001921:Brain / Q000378:metabolism; D064429:Fatty Acid Synthases / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009929:Organ Size; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D010179:Pancreas / Q000378:metabolism; D013154:Spleen / Q000378:metabolism; D013552:Swine; D013556:Swine, Miniature / Q000254:growth & development* / Q000378:metabolism*
D064429:Fatty Acid Synthases; D009955:Ornithine Decarboxylase