title: International Federation of Clinical Chemistry (IFCC): systematic top-down approach to clinical chemistry.
abstract: This paper introduces a systematic approach to organizing the discipline of clinical chemistry. The approach is called a top-down, systems approach because it starts at the top with the most general concepts and works down through less general concepts to the most specific details and techniques. The hypothesis is that the discipline can be organized into hierarchical levels of functional processes and operational approaches to those processes. The functional processes represent what clinical scientists do; the operational approaches represent how they do it. Because functional processes change little, if at all, with time, they are use to develop a stable infrastructure or framework for the discipline. That infrastructure is then used to organize and understand operational approaches that tend to change rapidly with time in response to technological advances. This paper begins with the most general functional processes and then uses selected examples of the more general functions to illustrate lower hierarchical levels of functional processes and operational approaches.
authors: Department of Chemistry, Purdue University, West Lafayette, IN 47907-1393.
authors: H L
authors: HL
authors: Pardue
authors: A
authors: A
authors: Truchaud
authors: K
authors: K
authors: Osawa
authors: J
authors: J
authors: Place
authors: P
authors: P
authors: Schnipelsky
mesh_terms: D000818:Animals; D002624:Chemistry, Clinical / Q000379:methods* / Q000458:organization & administration; D006801:Humans