Gas chromatographic/mass spectrometric confirmation of ten N-methylcarbamate insecticides in liver.
A gas chromatographic/mass spectrometric (GC/MS) confirmation procedure for 10 phenyl-N-methyl-carbamate insecticides in liver tissue was developed. The extract from liquid chromatography (LC) is purified with a C18 solid-phase extraction cartridge and then derivatized with heptafluorobutyric anhydride; the derivative is injected for analysis by GC/MS with electron ionization and multiple ion monitoring. The identity of the derivative is confirmed by comparison of its retention time and relative intensity data with those of a standard. Liver extracts from the LC procedure containing carbamates at 10 ppb levels were successfully confirmed by this procedure.
Bakowski
R S
RS
U.S. Department of Agriculture, Eastern Laboratory, Athens, GA 30604.
Ali
M S
MS
White
J D
JD
Phillippo
E T
ET
Ellis
R L
RL
D000818:Animals; D002219:Carbamates; D005506:Food Contamination / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D007306:Insecticides / Q000032:analysis*; D008099:Liver / Q000737:chemistry*
D002219:Carbamates; D007306:Insecticides