Effect of potential interference factors on performance of enzyme immunoassay and latex agglutination assay for cryptococcal antigen.
The PREMIER Cryptococcal Antigen Enzyme Immunoassay (Meridian Diagnostics) did not give discrepant results with rheumatoid factor, syneresis fluid, or serum macroglobulins from systemic lupus erythematosis patients. The Cryptococcal Antigen Latex Agglutination System (Meridian Diagnostics) did cross-react with syneresis fluid but not with the other serum factors tested.
Engler
H D
HD
Clinical Pathology Department, Warren Grant Magnuson Clinical Center, Bethesda, Maryland 20892.
Shea
Y R
YR
D000908:Antibodies, Fungal / Q000276:immunology; D000946:Antigens, Fungal / Q000032:analysis* / Q000097:blood / Q000134:cerebrospinal fluid; D003429:Cross Reactions; D003453:Cryptococcosis / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000276:immunology; D003455:Cryptococcus neoformans / Q000276:immunology* / Q000302:isolation & purification; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D006801:Humans; D007124:Immunoenzyme Techniques; D007841:Latex Fixation Tests; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology; D011933:Reagent Kits, Diagnostic; D012217:Rheumatoid Factor / Q000097:blood; D013587:Syphilis / Q000175:diagnosis
D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D011933:Reagent Kits, Diagnostic; D012217:Rheumatoid Factor