Pharmacology of current and future antithrombotic therapies.
This article reviews the mode of action of pharmacologic agents for anti-thrombotic therapy. It refers to both clinically established drugs and new approaches currently under preclinical or clinical development. Advantages and limitations of the different pharmacologic strategies are discussed with special attention to their effects on local interaction between the blood and the vessel wall.
Müller
T H
TH
German Red Cross Blood Transfusion Center, Odenburg.
Binder
K
K
Guth
B D
BD
D000818:Animals; D000925:Anticoagulants / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D013923:Thromboembolism / Q000628:therapy*; D015912:Thrombolytic Therapy
D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors