The African AIDS case definition and HIV serology in medical in-patients at Komfo Anokye Teaching Hospital, Kumasi, Ghana.
In 914 consecutive medical admissions to Komfo Anokye Teaching Hospital, the prevalence of infection with Human Immunodeficiency Virus type I (HIV-I) and Human Immunodeficiency Virus type 2 (HIV-2) was 12.6%. The prevalence in females was twice that found in males. The infection rate was maximum in the age group 25-29 years for females (45%) and 30-34 years for males (29%). There were 7 cases infected with HIV-2 alone, 55 cases infected with HIV-I alone and 53 cases with dual infection. The cases with HIV-2 infection tended to be older than those with HIV-I infection. For detecting HIV seropositivity in our patients the World Health Organization recommended case definition for AIDS in Africa gave a sensitivity of 32%, a specificity of 93% and a positive predictive value of 42%. The case definition gave the highest specificity and positive predictive values when cases of tuberculosis were not included in the analysis.
Ankrah
T C
TC
Department of Medicine, University of Science and Technology, Kumasi, Ghana.
Roberts
M A
MA
Antwi
P
P
Atubrah
M P
MP
Bawuah
P P
PP
Kotoh
S
S
Acheampong
J W
JW
Wood
J G
JG
Boateng
K A
KA
Mingle
J A
JA
D000293:Adolescent; D000328:Adult; D000368:Aged; D015897:Comorbidity; D005260:Female; D005869:Ghana / Q000453:epidemiology; D006679:HIV Seropositivity / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D015528:HIV Seroprevalence; D015497:HIV-1; D015498:HIV-2; D006784:Hospitals, Teaching; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D011159:Population Surveillance; D012680:Sensitivity and Specificity; D012737:Sex Factors; D014944:World Health Organization