Fine needle aspiration biopsy for diagnosis and follow-up of prostate cancer. Consensus Conference on Diagnosis and Prognostic Parameters in Localized Prostate Cancer. Stockholm, Sweden, May 12-13, 1993.
Fine needle aspiration biopsy (FNAB) and ultrasound-guided core biopsy using biopty gun both have a high, and approximately equal, accuracy in diagnosing and grading prostate cancer. The TRUS-guided technique provides a better estimation of the tumor extent and to some degree even of capsular involvement. It is therefore a recommendable part of the preoperative evaluation when radical prostatectomy is contemplated. On the other hand, the aspiration technique usually provides more epithelial cells. It entails a significantly lower risk of septic complications and of seeding tumor cells. It has also a lower cost than the core biopsies. The aspiration biopsy can easily be performed repeatedly in the follow-up procedure, which is of particular importance in cases managed with watchful waiting. We recommend the aspiration biopsy for routine use in the diagnostic work-up and follow-up. It is essential that not only the cytologic evaluation but as well the sampling from the prostate is performed with adequate expertise.
Andersson
L
L
WHO Collaborating Centre for Urological Tumors, Karolinska Hospital, Stockholm, Sweden.
Hagmar
B
B
Ljung
B M
BM
Skoog
L
L
D001707:Biopsy, Needle / Q000009:adverse effects / Q000191:economics; D003365:Costs and Cost Analysis; D005500:Follow-Up Studies; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D007239:Infections / Q000209:etiology; D008297:Male; D009366:Neoplasm Seeding; D011379:Prognosis; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D012017:Referral and Consultation; D013997:Time Factors