Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization.
The developmentally regulated mouse gene Nedd 1 encodes a protein showing similarities with the beta-subunit of heterotrimeric GTP-binding proteins and has growth suppressing activity when overexpressed in various cultured cell types. We have mapped the human homolog (NEDD1) of the mouse gene to chromosome 12q22 by fluorescence in situ hybridization using R-banded human (pro)metaphase chromosomes.
Takai
S
S
Department of Genetics, International Medical Center of Japan, Tokyo.
Yoshida
Y
Y
Noda
M
M
Yamada
K
K
Kumar
S
S
D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D004249:DNA Damage; D044387:GTP-Binding Protein beta Subunits; D019204:GTP-Binding Proteins / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D020962:Heterotrimeric GTP-Binding Proteins; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D051379:Mice; D008869:Microtubule-Associated Proteins; D009419:Nerve Tissue Proteins / Q000235:genetics*
D044387:GTP-Binding Protein beta Subunits; D008869:Microtubule-Associated Proteins; D009419:Nerve Tissue Proteins; C086844:Nedd1 protein, mouse; D019204:GTP-Binding Proteins; D020962:Heterotrimeric GTP-Binding Proteins