[The host-opportunistic protozoa system. The dissemination of Pneumocystis infection in white rats under the influence of drug-induced and biological immunosuppression].
The main purpose of the present study is the investigation of relationships of Pneumocystis carinii with the organism of white rat Wistar, which is natural carrier of this parasite. The series of experiments has shown that the immunosuppressor Tricort-40 (corticosteroid of prolonged activity) in a short time reactivates the Pneumocystis infection. The parasites have been observed in a great number in the lungs and rarely in the liver. The reactivation and dissemination of the Pneumocystis infection have been achieved constantly and with great expression by the combined immunosuppression of rats, by the medicamentous immunosuppression (injection of T-40) and biological one (infection with amastigotes Leishmania infantum). The developing mixed-infection (with pneumocysts and leishmania) could be the basis for the parasitocenological relationships.
Lysenko
A Ia
AIa
Lavdovskaia
M V
MV
Kovalenko
F P
FP
Chernov
Iu V
IuV
Strelkova
M V
MV
D017088:AIDS-Related Opportunistic Infections / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D000818:Animals; D003692:Delayed-Action Preparations; D004195:Disease Models, Animal; D005260:Female; D015497:HIV-1; D007108:Immune Tolerance / Q000187:drug effects*; D007165:Immunosuppression Therapy / Q000379:methods*; D018314:Leishmania infantum / Q000276:immunology; D008297:Male; D011010:Pneumocystis / Q000302:isolation & purification*; D016720:Pneumocystis Infections / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014222:Triamcinolone Acetonide / Q000494:pharmacology
D003692:Delayed-Action Preparations; D014222:Triamcinolone Acetonide
Sistema "khoziain--uslovno-patogennye prosteĭshie". Disseminatsiia pnevmotsistnoĭ infektsii u belykh krys pod vliianiem medikamentoznoĭ i biologicheskoĭ immunosupressii.