title: Subcutaneous infusion ports in the pediatric patient with hemophilia.
abstract: Central venous access devices have become important tools in the management of pediatric patients with malnutrition, malignancy, and infections requiring long-term antibiotic treatment. Hemophilia presents a lifetime challenge for venous access and at times can be an urgent or life-threatening situation. Since 1986, the authors have implanted 11 subcutaneous infusion ports in nine patients with hemophilia. The systems have remained in place for up to 7 years, without major complications or problems. Two catheters were replaced, after 4 and 6 years, because of skin erosion and blockage, respectively. One catheter was removed after 7 years because of blockage following local trauma and was not replaced. A recent survey through the Canadian Hemophilia Centre Directors Group obtained a further 45 subcutaneous infusion ports in other centers across Canada. The benefits of this system are overwhelming enthusiasm by the parents and children and no major complications. Some of the patients are now HIV-positive and are able to use their system for ongoing drug therapy.
authors: Children's Hospital of Western Ontario, Canada.
authors: D P
authors: DP
authors: Girvan
authors: L L
authors: LL
authors: deVeber
authors: M J
authors: MJ
authors: Inwood
authors: E A
authors: EA
authors: Clegg
mesh_terms: D002405:Catheterization, Central Venous / Q000295:instrumentation*; D002408:Catheters, Indwelling; D002648:Child; D004868:Equipment Failure; D005164:Factor IX / Q000378:metabolism; D005169:Factor VIII / Q000378:metabolism; D005500:Follow-Up Studies; D006467:Hemophilia A / Q000097:blood / Q000628:therapy*; D002836:Hemophilia B / Q000097:blood / Q000628:therapy*; D006801:Humans; D007601:Jugular Veins; D008297:Male
chemical_list: D005169:Factor VIII; D005164:Factor IX