title: Aspergillus discitis with acute disc abscess.
abstract: METHODS
  Aspergillus osteomyelitis of the vertebral body and disc space is rare. This report discusses a case that occurred in an immunosuppressed 29-year-old man and reviews the pertinent medical literature.
  
  
  OBJECTIVE
  To review the management and treatment of Aspergillus osteomyelitis of the vertebral body and disc space.
  
  
  BACKGROUND
  The patient presented with acute neurologic compromise resulting from L5-S1 discitis and a large epidural soft tissue component secondary to the Aspergillus infection.
  
  
  RESULTS
  The patient underwent aggressive surgical debridement along with treatment with amphotericin B and had a complete clinical recovery.
  
  
  CONCLUSIONS
  The authors recommend a combined medical-surgical approach in most cases of vertebral Aspergillus osteomyelitis. Early surgery with vigorous surgical debridement along with antifungal treatment seems to yield a good outcome.
authors: Department of Internal Medicine, Northeastern Ohio Universities College of Medicine, Canton.
authors: W
authors: W
authors: Assaad
authors: P S
authors: PS
authors: Nuchikat
authors: L
authors: L
authors: Cohen
authors: J V
authors: JV
authors: Esguerra
authors: F C
authors: FC
authors: Whittier
mesh_terms: D000038:Abscess / Q000382:microbiology* / Q000628:therapy; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D003646:Debridement; D015299:Discitis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D010019:Osteomyelitis / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D012447:Sacrum
chemical_list: D000666:Amphotericin B