Oral contraceptive-dependent growth of focal nodular hyperplasia.
A 22 year old woman was incidentally found to have a hepatic small haemangioma-like mass, measuring 1.4 cm in diameter, by an ultrasonographic examination. The mass demonstrated no change in size or appearance for 6 months until the patient began to take oral contraceptives. Eventually, the mass increased to 2.0 cm in diameter after using oral contraceptives for 6 months. A histological examination suggested the mass to be typical focal nodular hyperplasia, and not hepatic adenoma. There was no further change in either size or appearance in the ensuing 1 year after the discontinuation of oral contraceptives.
Nakamuta
M
M
Department of Internal Medicine, Fukuoka City Hospital, Japan.
Ohashi
M
M
Fukutomi
T
T
Tanabe
Y
Y
Hiroshige
K
K
Nakashima
O
O
Nawata
H
H
D000328:Adult; D003276:Contraceptives, Oral / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology; D008099:Liver / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology*; D014463:Ultrasonography
D003276:Contraceptives, Oral