title: Control of melanosome movements in isolated skin melanophores of a catfish Clarias batrachus (Linn.).
abstract: Adrenergic and cholinergic receptors have been studied in isolated skin melanophores of a catfish Clarias batrachus. Catecholamines induced a strong aggregatory effect on the melanophores. Melanosome aggregation induced by adrenaline and noradrenaline was partially blocked by alpha adrenergic receptor blockers and a beta receptor blocker. Cholinomimetic drugs aroused a significant dispersion of melanophroes. Atropine effectively blocked the dispersal, responses of melanophores to acetylcholine and carbachol, while, hexamethonium blocked the nocotine induced dispersal responses of the melanophores.
authors: Department of Biosciences, Barkatullah University, Bhopal.
authors: M
authors: M
authors: Ovais
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002217:Carbachol / Q000494:pharmacology; D002395:Catecholamines / Q000494:pharmacology*; D002397:Catfishes; D004347:Drug Interactions; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D018738:Hexamethonium / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008544:Melanocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008547:Melanophores / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D009538:Nicotine / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000502:physiology; D011950:Receptors, Cholinergic / Q000502:physiology; D012867:Skin / Q000166:cytology / Q000378:metabolism
chemical_list: D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D002395:Catecholamines; D011941:Receptors, Adrenergic; D011950:Receptors, Cholinergic; D018738:Hexamethonium; D009538:Nicotine; D001285:Atropine; D002217:Carbachol; D000109:Acetylcholine; D009638:Norepinephrine; D004837:Epinephrine