Mechanisms of formation of 1,N6-ethenoadenine, 3,N4-ethenocytosine, 1,N2-ethenoguanine and N2,3-ethenoguanine DNA adducts from substituted oxiranes.
Persmark
M
M
Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN.
Humphreys
W G
WG
Okazaki
O
O
Raney
V M
VM
Guengerich
F P
FP
D000225:Adenine / Q000031:analogs & derivatives* / Q000737:chemistry; D003596:Cytosine / Q000031:analogs & derivatives* / Q000737:chemistry; D018736:DNA Adducts / Q000138:chemical synthesis*; D005027:Ethylene Oxide / Q000737:chemistry*; D006147:Guanine / Q000031:analogs & derivatives* / Q000737:chemistry; D006151:Guanosine / Q000031:analogs & derivatives* / Q000737:chemistry; D009153:Mutagens / Q000737:chemistry*
C018289:3,N(4)-ethenocytosine; D018736:DNA Adducts; D009153:Mutagens; C015196:N(2),3-ethenoguanine; D006151:Guanosine; C004981:1,N(6)-ethenoadenine; D006147:Guanine; C079488:1,N(2)-ethenoguanosine; D003596:Cytosine; D000225:Adenine; D005027:Ethylene Oxide