[Erythrokeratolysis hiemalis. Erythematosquamous genetic dermatosis with seasonal manifestation].
Erythrokeratolysis hiemalis, keratolytic winter erythema or Oudtshoorn skin has been reported from the South African district of Oudtshoorn as a dominantly inherited dermatosis beginning in early childhood, in some cases with circinar scaling erythemas. Seasonal manifestation in winter-time and a characteristic multi-form histology distinguish this dermatosis from other childhood scaling erythemas. We present clinical, histological and preliminary immunohistological data of a 4-year-old girl with the attributes of erythrokeratolysis hiemalis. No ancestors from the endemic region were traced. The lack of further cases in the family is interpreted as indicative of a spontaneous dominant new mutation.
Krahl
D
D
Universitäts-Hautklinik, Heidelberg.
Sigwart
A
A
Hartschuh
W
W
Anton-Lamprecht
I
I
Petzoldt
D
D
D002675:Child, Preschool; D003873:Dermatitis, Exfoliative / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007150:Immunohistochemistry; D017493:Leukocyte Common Antigens / Q000235:genetics; D008854:Microscopy, Electron; D010507:Periodicity; D012621:Seasons; D012867:Skin / Q000473:pathology
D017493:Leukocyte Common Antigens
Erythrokeratolysis hiemalis. Erythematosquamöse Genodermatose mit saisonaler Manifestation.