title: Effect of Escherichia coli enterotoxins on macromolecular absorption.
abstract: Macromolecular absorption of gliadin, a wheat protein and alpha lactalbumin, a milk protein was evaluated in control and Escherichia coli enterotoxin (heat-stable, heat-labile, and both heat-stable and heat-labile enterotoxin) treated mice. The peak concentration of gliadin and lactalbumin was two hours and three hours after their ingestion, respectively. There was also a significant increase (p < 0.01) in the absorption of both the proteins in all the three toxin treated groups compared with the control group. These results suggest that intestinal permeability and macromolecular absorption changes after E coli infection.
authors: Department of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors: M
authors: M
authors: Verma
authors: S
authors: S
authors: Majumdar
authors: N K
authors: NK
authors: Ganguly
authors: B N
authors: BN
authors: Walia
mesh_terms: D000818:Animals; D001427:Bacterial Toxins / Q000494:pharmacology*; D004768:Enterotoxins / Q000494:pharmacology*; D004926:Escherichia coli; D029968:Escherichia coli Proteins; D005903:Gliadin / Q000097:blood; D007408:Intestinal Absorption / Q000187:drug effects*; D007421:Intestine, Small / Q000378:metabolism; D007768:Lactalbumin / Q000097:blood; D046911:Macromolecular Substances; D051379:Mice
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; D046911:Macromolecular Substances; C034151:heat stable toxin (E coli); D005903:Gliadin; D007768:Lactalbumin; C027538:heat-labile enterotoxin, E coli