Ah receptor: a novel ligand-activated transcription factor.
Two years have passed since the Ah receptor (AhR) and the AhR nuclear translocator (Arnt) were revealed to constitute a novel ligand-activated transcription factor by molecular biological studies on cloned cDNAs. Many interesting properties of the AhR/Arnt system have begun to be elucidated. We present here a brief summary of the molecular biology of AhR and Arnt.
Fujii-Kuriyama
Y
Y
Department of Chemistry, Faculty of Science, Tohoku University, Sendai, Japan.
Ema
M
M
Mimura
J
J
Sogawa
K
K
D000595:Amino Acid Sequence; D000818:Animals; D051784:Aryl Hydrocarbon Receptor Nuclear Translocator; D004268:DNA-Binding Proteins; D006801:Humans; D008969:Molecular Sequence Data; D018336:Receptors, Aryl Hydrocarbon / Q000235:genetics / Q000502:physiology*; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology*
C497396:ARNT protein, human; D004268:DNA-Binding Proteins; D018336:Receptors, Aryl Hydrocarbon; D014157:Transcription Factors; D051784:Aryl Hydrocarbon Receptor Nuclear Translocator