title: Whole-body protein turnover in elderly men and women: responses to two protein intakes.
abstract: In this study the effect of protein intake (12% and 21% of total energy intake, diets A and B, respectively) on nitrogen balance and on whole-body protein turnover (PT) was measured in 17 elderly men and 11 elderly women (mean +/- SD: 74 +/- 12 y and 68 +/- 9 y, respectively) with different levels of physical activity. Mean (+/- SD) nitrogen balance (diet A: -0.004 +/- 0.027 g.kg-1.d-1, diet B: 0.011 +/- 0.064 g.kg-1.d-1) did not differ significantly from zero during either diet. PT increased significantly when the protein content of the diet increased from 12% to 21% of total energy (P < 0.0001). There was a positive correlation between protein intake and PT (diet A: synthesis and breakdown, P < 0.01; diet B: synthesis, P < 0.001; breakdown, P < 0.0001). PT rates were significantly higher for men when compared with women, even when corrections were made for differences in body composition (P < 0.05).
authors: Department of Human Biology, University of Limburg, Maastricht, Netherlands.
authors: D L
authors: DL
authors: Pannemans
authors: D
authors: D
authors: Halliday
authors: K R
authors: KR
authors: Westerterp
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018592:Cross-Over Studies; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D002149:Energy Intake; D004734:Energy Metabolism; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D014176:Protein Biosynthesis; D012737:Sex Factors
chemical_list: D004044:Dietary Proteins; D009584:Nitrogen