title: Asplenia syndrome and isolated total anomalous pulmonary venous connection in siblings.
abstract: We report on a family with asplenia syndrome in one and total anomalous pulmonary venous connection (TAPVC) in the other sib. Both conditions are rare, may have a genetic cause and belong to a spectrum of laterality disorders. This suggests that both asplenia syndrome and TAPVC in this family are the clinical expression of a single genetic disorder.
authors: Department of Paediatrics, University Hospital Leuven, Belgium.
authors: K
authors: K
authors: Devriendt
authors: A
authors: A
authors: Casaer
authors: A
authors: A
authors: Van Cauter
authors: F
authors: F
authors: de Zegher
authors: M
authors: M
authors: Dumoulin
authors: M
authors: M
authors: Gewillig
authors: H
authors: H
authors: Devlieger
mesh_terms: D006330:Heart Defects, Congenital / Q000235:genetics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities* / Q000098:blood supply; D008297:Male; D010375:Pedigree; D012857:Situs Inversus / Q000150:complications / Q000235:genetics*; D013154:Spleen / Q000002:abnormalities*; D013577:Syndrome