Contact allergy to 2-hydroxy-5-tert-butyl benzylalcohol and 2,6-bis(hydroxymethyl)-4-tert-butylphenol, components of a phenolic resin used in marking pens.
2-hydroxy-5-tert-butyl benzylalcohol and 2,6-bis(hydroxymethyl)-4-tert-butylphenol were identified as contact allergens in a phenolic resin used as a tackifier in the ink of a marking pen, which, after being used directly on the skin, caused an acute contact dermatitis on the hand of a 13-year-old boy. The patient also reacted to 4-tert-butylphenol-formaldehyde resin (BPF resin) 1% pet. included in the European standard series.
Hagdrup
H
H
Department of Dermatology, Odense University Hospital, Denmark.
Egsgaard
H
H
Carlsen
L
L
Andersen
K E
KE
D000208:Acute Disease; D000293:Adolescent; D000485:Allergens; D002084:Butylated Hydroxytoluene / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000378:metabolism; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D006229:Hand Dermatoses / Q000209:etiology*; D006801:Humans; D007281:Ink; D008297:Male
D000485:Allergens; D002084:Butylated Hydroxytoluene; C091483:2,6-bis(hydroxymethyl)-4-tert-butylphenol; C091482:2-hydroxy-5-tert-butylbenzyl alcohol