title: Localized Mycobacterium avium-intracellulare mastitis in an immunocompetent woman with silicone breast implants.
abstract: While M. avium-intracellulare has received increasing recognition due to its association with AIDS, silicone breast implants have come under increased FDA scrutiny, requiring new safety and efficacy protocols. We report a case of localized M. avium-intracellulare mastitis associated with a breast implant in an immunocompetent, HIV-negative woman who was cured with implant removal and a long course (6 months) of clarithromycin. Serous exudates occurring in association with breast implants should be cultured for acid-fast organisms. Clarithromycin may be a therapeutic adjunct to effectively cure these infections.
authors: Department of Family Practice, Santa Monica Hospital Medical Center, Calif.
authors: D
authors: D
authors: Lee
authors: E J
authors: EJ
authors: Goldstein
authors: H A
authors: HA
authors: Zarem
mesh_terms: D000328:Adult; D018427:Breast Implants; D017291:Clarithromycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008413:Mastitis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D009164:Mycobacterium Infections / Q000276:immunology; D015270:Mycobacterium avium-intracellulare Infection / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D011475:Prosthesis Failure; D012828:Silicones
chemical_list: D012828:Silicones; D017291:Clarithromycin