title: The African AIDS case definition and HIV serology in medical in-patients at Komfo Anokye Teaching Hospital, Kumasi, Ghana.
abstract: In 914 consecutive medical admissions to Komfo Anokye Teaching Hospital, the prevalence of infection with Human Immunodeficiency Virus type I (HIV-I) and Human Immunodeficiency Virus type 2 (HIV-2) was 12.6%. The prevalence in females was twice that found in males. The infection rate was maximum in the age group 25-29 years for females (45%) and 30-34 years for males (29%). There were 7 cases infected with HIV-2 alone, 55 cases infected with HIV-I alone and 53 cases with dual infection. The cases with HIV-2 infection tended to be older than those with HIV-I infection. For detecting HIV seropositivity in our patients the World Health Organization recommended case definition for AIDS in Africa gave a sensitivity of 32%, a specificity of 93% and a positive predictive value of 42%. The case definition gave the highest specificity and positive predictive values when cases of tuberculosis were not included in the analysis.
authors: Department of Medicine, University of Science and Technology, Kumasi, Ghana.
authors: T C
authors: TC
authors: Ankrah
authors: M A
authors: MA
authors: Roberts
authors: P
authors: P
authors: Antwi
authors: M P
authors: MP
authors: Atubrah
authors: P P
authors: PP
authors: Bawuah
authors: S
authors: S
authors: Kotoh
authors: J W
authors: JW
authors: Acheampong
authors: J G
authors: JG
authors: Wood
authors: K A
authors: KA
authors: Boateng
authors: J A
authors: JA
authors: Mingle
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015897:Comorbidity; D005260:Female; D005869:Ghana / Q000453:epidemiology; D006679:HIV Seropositivity / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D015528:HIV Seroprevalence; D015497:HIV-1; D015498:HIV-2; D006784:Hospitals, Teaching; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D011159:Population Surveillance; D012680:Sensitivity and Specificity; D012737:Sex Factors; D014944:World Health Organization