Anticomplement activity in human aqueous humor.
Twenty-six samples of human aqueous humor from patients with cataract and glaucoma were analyzed on anticomplement activity. The mean inhibitory rate was 15.32 +/- 14.60%, ranging from 0.93 to 60.02%. The inhibitory effect appeared in a dose-dependent manner. No significant differences were found between males and females (p > 0.05) and between samples of different age (p > 0.05). We revealed that aqueous humor had an inhibitory effect on complement activity. This indicates that human aqueous humor has an immune regulatory function.
Zheng
X B
XB
Research Laboratory of Immunology, Shanxi Institute of Ophthalmology, China.
Peng
Q
Q
Sha
L
L
D000328:Adult; D001082:Aqueous Humor / Q000276:immunology*; D002386:Cataract / Q000276:immunology; D003169:Complement Inactivator Proteins / Q000276:immunology*; D003165:Complement System Proteins / Q000096:biosynthesis*; D005260:Female; D005901:Glaucoma / Q000276:immunology; D006801:Humans; D008297:Male
D003169:Complement Inactivator Proteins; D003165:Complement System Proteins