title: Peri-operative effect of major gastrointestinal surgery on serum magnesium.
abstract: This study investigates the changes in serum magnesium levels after major gastrointestinal surgery and evaluates if Plasma-Lyte 148 used as maintenance fluid influences these changes in the peri-operative period. Thirty patients presenting for procedures ranging from anterior rectal resection to thoraco-abdominal cardio-oesophagectomy were randomly allocated into two groups, one of which received compound sodium lactate solution as the maintenance crystalloid during the intra- and postoperative period, and the other Plasma-Lyte 148, a magnesium-containing crystalloid solution. Serum magnesium levels were measured pre-operatively, in the immediate recovery period and 24 h postoperatively. The results showed a statistically significant (p < 0.05) reduction in the magnesium levels in both groups. The reduction was less marked in the Plasma-Lyte group but this did not achieve statistical significance (p > 0.05) compared with the compound sodium lactate group.
authors: Department of Anaesthesia, Royal Oldham Hospital, Lancashire.
authors: A
authors: A
authors: Sanchez-Capuchino
authors: I
authors: I
authors: McConachie
mesh_terms: D000085:Acetates / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D013505:Digestive System Surgical Procedures; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D005942:Gluconates / Q000627:therapeutic use; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D007773:Lactates / Q000627:therapeutic use; D019344:Lactic Acid; D008274:Magnesium / Q000097:blood*; D015636:Magnesium Chloride / Q000627:therapeutic use; D008275:Magnesium Deficiency / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods; D011184:Postoperative Period; D011189:Potassium Chloride / Q000627:therapeutic use; D019346:Sodium Acetate; D012965:Sodium Chloride / Q000627:therapeutic use
chemical_list: D000085:Acetates; D005942:Gluconates; D007773:Lactates; C012499:Plasma-lyte 148; D015636:Magnesium Chloride; D019344:Lactic Acid; D012965:Sodium Chloride; D019346:Sodium Acetate; D011189:Potassium Chloride; D008274:Magnesium