Clear cell hepatocellular carcinoma treated with liver transplantation.
We report a case of a 35-year-old female who underwent total hepatectomy and liver transplantation for a diffuse clear cell variant of hepatocellular carcinoma in non-cirrhotic liver. Preoperative clinical evaluation showed no extrahepatic metastatic involvement. However, scheletal metastases of the tumour were detected five months later. Although clear cell variant is generally considered to run a relatively favorable course, this case proved rapidly progressive and seems therefore to be a debatable candidate for liver transplantation among primary hepatic cancers.
Pecorella
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Dipartimento di Biopatologia Umana, Università degli Studi La Sapienza, di Roma.
Ciardi
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A
Aiello
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E
Piras
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MR
Farci
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C
Di Tondo
U
U
D018262:Adenocarcinoma, Clear Cell / Q000453:epidemiology / Q000473:pathology*; D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology / Q000601:surgery*; D016031:Liver Transplantation