title: Further studies on new furostanol saponins from the bulbs of Allium macrostemon.
abstract: Further studies by means of preparative HPLC led to the isolation of two new furostanol saponins, macrostemonoside J (1) and L (3), along with an artifact, macrostemonoside K (2) from the bulbs of Allium macrostemon. On the basis of chemical evidence and spectral analysis (1H-, 13C-NMR and FAB-MS), the structure of 1 was elucidated to be 26-O-beta-D-glucopyranosyl 2 beta,3 beta,22,26-tetrahydroxy-25(R)-5 beta-furostan 3-O-beta-D-glucopyranosyl (1-->2)-beta-D-galactopyranoside. 3 was deduced to be 26-O-beta-D-glucopyranosyl 2 beta,3 beta,26-trihydroxy-25(R)-5 beta-furostan- 20(22)-ene 3-O-beta-D-glucopyranosyl (1-->2)-beta-D-galactopyranoside.
authors: Department of Pharmacology of Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang.
authors: J
authors: J
authors: Peng
authors: X
authors: X
authors: Yao
authors: Y
authors: Y
authors: Okada
authors: T
authors: T
authors: Okuyama
mesh_terms: D000490:Allium / Q000737:chemistry*; D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013329:Structure-Activity Relationship
chemical_list: D010936:Plant Extracts; D012503:Saponins