title: Production of a murine monoclonal antibody to the low-incidence red cell antigen Wra: characterisation and comparison with human anti-Wra.
abstract: The production of a monoclonal antibody which detects the low-incidence red cell antigen Wra is described. The antibody (BGU1-WR) was isolated following immunization of BALB/tk mice with Wr(a+) cells. BGU1-WR is an IgG1 antibody and reacted in a manner similar to human polyclonal anti-Wra with untreated, protease treated and chemically modified Wr(a+) cells.
authors: MRC Blood Group Unit, University College London, UK.
authors: S M
authors: SM
authors: Ring
authors: C A
authors: CA
authors: Green
authors: D M
authors: DM
authors: Swallow
authors: P
authors: P
authors: Tippett
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D015994:Incidence; D007519:Isoantigens / Q000097:blood*; D051379:Mice; D008807:Mice, Inbred BALB C; D013045:Species Specificity
chemical_list: D000911:Antibodies, Monoclonal; D007519:Isoantigens