Sesquiterpene lactone mix is not an adequate screen for Compositae allergy.
70 patients suspected or known to have contact allergy to Compositae were patch tested with 0.1% sesquiterpene lactone mix (SL mix) and individual Compositae oleoresins. There were no apparent cases of active sensitization by, or irritancy from, the SL mix. 6 patients had allergic reactions to both SL mix and Compositae oleoresins, while 11 patients had allergic reactions to Compositae oleoresins with a negative reaction to the SL mix. In all but 2 of these, Compositae allergy was considered clinically relevant. As 0.1% SL mix picked up only 35% of cases of Compositae allergy, we do not consider it an adequate screen.
Green
C
C
Department of Dermatology, Ninewells Hospital and Medical School, Dundee, UK.
Ferguson
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010936:Plant Extracts / Q000276:immunology*; D012717:Sesquiterpenes / Q000276:immunology*
D010936:Plant Extracts; D012717:Sesquiterpenes; C018620:oleoresins