title: The effect of the sweetness inhibitor 2(-4-methoxyphenoxy)propanoic acid (sodium salt) (Na-PMP) on the taste of bitter-sweet stimuli.
abstract: The effect of the sweetness inhibitor 2(-4-methoxyphenoxy)propanoic acid (sodium salt) (Na-PMP) on the taste and temporal properties of a range of bitter-sweet stimuli was determined using a trained sensory panel. Na-PMP was found to be an effective inhibitor of the sweetness response of all stimuli tested, reducing both sweetness intensity and persistence. The inhibitor was found to be specific to sweet taste, no reduction in bitterness intensity or persistence was observed at the concentrations of Na-PMP employed in this study. The results therefore do not support the claim of Fuller and Kurtz (1991), that Na-PMP is a potent bitterness inhibitor, but rather support the existence of two distinct receptor sites/loci in sweet and bitter chemoreception.
authors: Department of Food Science and Technology, University of Reading, Berks, UK.
authors: C
authors: C
authors: Johnson
authors: G G
authors: GG
authors: Birch
authors: D B
authors: DB
authors: MacDougall
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010647:Phenyl Ethers; D011422:Propionates / Q000494:pharmacology*; D013549:Sweetening Agents / Q000494:pharmacology*; D013649:Taste / Q000187:drug effects*
chemical_list: D010647:Phenyl Ethers; D011422:Propionates; D013549:Sweetening Agents; C091421:2-(4-methoxyphenoxy)propanoic acid