title: Childhood sarcoidosis presenting with hypercalcaemic crisis.
abstract: We report a case of hypercalcaemic crisis due to sarcoidosis in a 15-year-old boy. The clinical suspicion of sarcoidosis was confirmed by a liver biopsy. At admission serum calcium, 1,25(OH)2 and ACE were elevated and iPTH was suppressed. The levels of serum total and ionized calcium, iPTH, ACE, 1,25(OH)2 and 25-OH were followed and chest X-ray and pulmonary function tests were performed during systemic steroid treatment. The clinical condition improved during treatment and the paraclinical measurements normalised within 5 weeks. The mechanism whereby hypercalcaemia occurs in childhood sarcoidosis is clarified.
authors: Department of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
authors: A L
authors: AL
authors: Hoffmann
authors: N
authors: N
authors: Milman
authors: H E
authors: HE
authors: Nielsen
authors: J
authors: J
authors: Thode
mesh_terms: D000293:Adolescent; D003718:Denmark / Q000453:epidemiology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D015994:Incidence; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D011241:Prednisone