Povidone-iodine in umbilical cord care interferes with neonatal screening for hypothyroidism.
Out of 1346 newborns screened for congenital hypothyroidism, 31 non-hypothyroid infants were summoned because of a thyroid stimulating hormone (TSH) level above 10 microU/ml. False-positive TSH levels were significantly more frequent in the babies treated with povidone-iodine (4.6%) than in those treated with either alcohol or triple dye (0.7%). CONCLUSION. Iodine containing solutions should be avoided in umbilical cord care of the newborn.
Lin
C P
CP
Department of Paediatrics, Taipei Municipal Chung-Hsiao Hospital, Taiwan, Rupublic of China.
Chen
W
W
Wu
K W
KW
D006801:Humans; D007037:Hypothyroidism / Q000097:blood* / Q000175:diagnosis; D007231:Infant, Newborn; D015997:Neonatal Screening; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000009:adverse effects*; D011446:Prospective Studies; D013972:Thyrotropin / Q000097:blood*; D014470:Umbilical Cord
D011206:Povidone-Iodine; D013972:Thyrotropin