Childhood sarcoidosis presenting with hypercalcaemic crisis.
We report a case of hypercalcaemic crisis due to sarcoidosis in a 15-year-old boy. The clinical suspicion of sarcoidosis was confirmed by a liver biopsy. At admission serum calcium, 1,25(OH)2 and ACE were elevated and iPTH was suppressed. The levels of serum total and ionized calcium, iPTH, ACE, 1,25(OH)2 and 25-OH were followed and chest X-ray and pulmonary function tests were performed during systemic steroid treatment. The clinical condition improved during treatment and the paraclinical measurements normalised within 5 weeks. The mechanism whereby hypercalcaemia occurs in childhood sarcoidosis is clarified.
Hoffmann
A L
AL
Department of Pediatrics, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
Milman
N
N
Nielsen
H E
HE
Thode
J
J
D000293:Adolescent; D003718:Denmark / Q000453:epidemiology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D015994:Incidence; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology
D011241:Prednisone