Etest for susceptibility testing of Mycobacterium tuberculosis and Mycobacterium avium-intracellulare.
Methods currently used for susceptibility testing of Mycobacterium, including agar dilution and the Bactec radiometric method, are based on the proportion technique using a single critical concentration of antibiotic. Preliminary studies were conducted with Mycobacterium species by using the Etest method, a gradient minimum inhibitory concentration technique, well described for susceptibility testing of other fastidious and slow-growing organisms. Excellent correlation was demonstrated between Etest and agar dilution with rifampin-susceptible and -resistant isolates of M. tuberculosis and ciprofloxacin-resistant and -susceptible isolates of Mycobacterium avium-intracellulare.
Wanger
A
A
Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston 77225.
Mills
K
K
D002939:Ciprofloxacin / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D015269:Mycobacterium avium Complex / Q000187:drug effects*; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D012293:Rifampin / Q000494:pharmacology*
D002939:Ciprofloxacin; D012293:Rifampin