Successful treatment of a cardiac angiosarcoma with combined modality therapy.
The patient was a 34-year-old man with a primary angiosarcoma of the heart. Initial admission was for cardiac tamponade. He was treated with preoperative chemotherapy and radiation therapy and then underwent orthotopic heart transplantation. The patient had an uneventful postoperative recovery, received two postoperative regimens of chemotherapy, and, at 33 months after transplantation, had no evidence of recurrence or metastasis. We propose that a more aggressive management of these patients with difficult conditions is warranted.
Baay
P
P
Department of Surgery, University of Utah Medical Center, Salt Lake City 84132.
Karwande
S V
SV
Kushner
J P
JP
Olsen
S
S
Renlund
D G
DG
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003606:Dacarbazine / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005500:Follow-Up Studies; D006338:Heart Neoplasms / Q000532:radiotherapy / Q000628:therapy*; D016027:Heart Transplantation; D006394:Hemangiosarcoma / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008297:Male; D015080:Mesna / Q000008:administration & dosage; D011879:Radiotherapy Dosage
D003606:Dacarbazine; D004317:Doxorubicin; D015080:Mesna; D007069:Ifosfamide