Androgenic enhancement of motor neuron regeneration.
In conclusion, the available evidence to date suggests that many of the aspects of neuronal functioning affected by gonadal steroids under steady state conditions are also significantly affected by steroids under stress conditions such as axon disconnection. This argues toward a therapeutic usefulness of gonadal steroids in activating and/or accelerating the reparative response of neurons to injury, a concept that will be exciting to test in future clinical studies.
Jones
K J
KJ
Department of Cell Biology, Neurobiology and Anatomy, Loyola University of Chicago, Stritch School of Medicine, Maywood, Illinois 60153.
D000728:Androgens / Q000502:physiology*; D000818:Animals; D012739:Gonadal Steroid Hormones / Q000502:physiology; D008297:Male; D009046:Motor Neurons / Q000502:physiology*; D009416:Nerve Regeneration / Q000502:physiology*
D000728:Androgens; D012739:Gonadal Steroid Hormones