Electro-oculographic changes after local excision of uveal melanoma.
Standard electro-oculography was performed in 10 patients with malignant unilateral uveal melanoma All eyes were treated by means of surgical local excision. After a mean +/- standard deviation follow-up of 10.5 +/- 5.5 months (range, 6 to 20 months) in the five patients with choroidal melanoma, the electro-oculographic recordings, which had appeared reduced or flat before the surgery, increased significantly just after the local excision. Thereafter the amplitudes of the electro-oculographic light peaks were reduced in all cases up to extinction, possibly because of a retinal detachment. On the contrary, the electro-oculographic value in the five melanomas localized at the iris and ciliary body, normal before the surgery, showed a marked and persistent increase after surgery, probably related to an 'electric hole' in the globe.
Spadea
L
L
Clinica Oculistica, Ospedale San Salvotore, L'Aquila, Italy.
D'Amico
M
M
Dragani
T
T
Balestrazzi
E
E
D004585:Electrooculography; D005133:Eye Movements / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008545:Melanoma / Q000503:physiopathology* / Q000601:surgery*; D008875:Middle Aged; D011446:Prospective Studies; D014604:Uveal Neoplasms / Q000503:physiopathology* / Q000601:surgery*