title: Quantitative diagnosis of Schistosoma infections by measurement of circulating antigens in serum and urine.
abstract: Recent research on the detection of the schistosome circulating antigens, circulating anodic antigen (CAA) and circulating cathodic antigen (CCA), has greatly expanded the scope of applications. In the present paper aspects of assay development, in particular of highly sensitive assays and of field-applicable assays, are discussed. The progress in the use of CAA- and CCA-detection for diagnosis, follow-up of chemotherapy and sero-epidemiological studies is evaluated.
authors: Department of Parasitology, University of Leiden, The Netherlands.
authors: A M
authors: AM
authors: Deelder
authors: Z L
authors: ZL
authors: Qian
authors: P G
authors: PG
authors: Kremsner
authors: L
authors: L
authors: Acosta
authors: A L
authors: AL
authors: Rabello
authors: P
authors: P
authors: Enyong
authors: P P
authors: PP
authors: Simarro
authors: E C
authors: EC
authors: van Etten
authors: F W
authors: FW
authors: Krijger
authors: J P
authors: JP
authors: Rotmans
mesh_terms: D000818:Animals; D000947:Antigens, Helminth / Q000097:blood* / Q000652:urine*; D002986:Clinical Trials as Topic; D004797:Enzyme-Linked Immunosorbent Assay; D015200:Fluoroimmunoassay; D005500:Follow-Up Studies; D006023:Glycoproteins / Q000097:blood* / Q000652:urine*; D015801:Helminth Proteins / Q000097:blood* / Q000652:urine*; D006801:Humans; D012547:Schistosoma / Q000276:immunology*; D012552:Schistosomiasis / Q000097:blood* / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology / Q000652:urine*; D012680:Sensitivity and Specificity; D016036:Seroepidemiologic Studies
chemical_list: D000947:Antigens, Helminth; C091532:CCA protein, Schistosoma mansoni; D006023:Glycoproteins; D015801:Helminth Proteins; C090907:circulating anodic antigen, Schistosoma mansoni