Cowden's syndrome: a case report with clinical, histopathologic and immunological studies.
Cowden's syndrome is a rare autosomal dominant condition characterised by multiple hamartomas of the gastrointestinal tract and cancer of the breast and thyroid. We present a patient with multiple papillomatous lesions of the hard palate, facial papules, and a history of breast cancer and papillomas of the uterine cavity. We also report the results of light and electron microscopy of the palatal lesions and immunological studies of patient's T-lymphocyte function.
Saccardi
A
A
Department of Stomatology, University of Florence.
Bacci
S
S
Romagnoli
P
P
Ravina
A
A
Ficarra
G
G
D001943:Breast Neoplasms / Q000276:immunology / Q000473:pathology; D005145:Face; D005260:Female; D006223:Hamartoma Syndrome, Multiple / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000097:blood; D008875:Middle Aged; D009055:Mouth / Q000473:pathology; D014594:Uterine Neoplasms / Q000276:immunology / Q000473:pathology
D007136:Immunoglobulins