title: Lack of association between the I/D polymorphism of the angiotensin-converting enzyme gene and essential hypertension in a Belgian population.
abstract: We tested the insertion/deletion (I/D) polymorphism of the ACE gene in 119 hypertensive patients and in 109 normotensive controls by means of the polymerase chain reaction (PCR). The allele and genotype frequencies of the I/D polymorphism in the ACE gene are essentially identical in both groups, regardless of age or sex. The I/D polymorphism of the ACE gene is thus not implicated in Belgian hypertensive patients.
authors: Centre for Human Genetics, University of Leuven, Belgium.
authors: X X
authors: XX
authors: Gu
authors: M
authors: M
authors: Spaepen
authors: C
authors: C
authors: Guo
authors: R
authors: R
authors: Fagard
authors: A
authors: A
authors: Amery
authors: P
authors: P
authors: Lijnen
authors: J J
authors: JJ
authors: Cassiman
mesh_terms: D001483:Base Sequence; D006801:Humans; D006973:Hypertension / Q000235:genetics*; D008969:Molecular Sequence Data; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D011110:Polymorphism, Genetic
chemical_list: D007703:Peptidyl-Dipeptidase A