Cutaneous T-cell lymphoma diagnosed by fine-needle aspiration: a case report with clinical, cytological, and immunophenotypic features.
A case study of cutaneous T-cell lymphoma in a 40-yr-old Indian male is presented. Prominent clinical features consisted of large skin tumours, lymphadenopathy, and a rapidly progressive course of development. Aspiration smears from tumours, lymph nodes, and bone marrow showed pleomorphic Sezary cells and lymphoid blasts. The neoplastic cells stained positively with anti-HLA DR, CD1, and CD2 antibodies and showed lack of T-cell subset antigens CD4 and CD8. Numerous proliferating cells were identified with 56% of bone marrow cells and 57% of cells in the dermis staining positively with Ki-67 and PC10 antibodies, respectively. This case is reported in view of its uncommon features.
Basu
D
D
Department of Pathology, Maulana Azad Medical College, New Delhi, India.
Kumar
S
S
Shome
D K
DK
Chauhan
S
S
D000328:Adult; D001707:Biopsy, Needle; D003584:Cytological Techniques; D006801:Humans; D016130:Immunophenotyping; D016410:Lymphoma, T-Cell, Cutaneous / Q000737:chemistry / Q000473:pathology*; D008297:Male; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology*