A pharmacogenetic basis for the safe and effective use of azathioprine and other thiopurine drugs in dermatologic patients.
Snow
J L
JL
Department of Dermatology, Mayo Clinic, Rochester, MN 55905.
Gibson
L E
LE
D000483:Alleles; D001379:Azathioprine / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D004912:Erythrocytes / Q000187:drug effects / Q000201:enzymology; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D015122:Mercaptopurine / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D008780:Methyltransferases / Q000097:blood / Q000235:genetics / Q000378:metabolism*; D011110:Polymorphism, Genetic; D012871:Skin Diseases / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism
D015122:Mercaptopurine; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D001379:Azathioprine