Meta-analysis of systemic anti-fibrinolytics in traumatic hyphaema.
We report a meta-analysis of randomised, controlled, clinical trials of systemic anti-fibrinolytics in traumatic hyphaema. Outcome measures were rate of secondary haemorrhage and final visual acuity. An estimate of the overall odds ratio for each outcome measure was calculated both by combining the logarithms of the odds ratios, and by the Mantel-Haenszel method. The results confirm a beneficial effect of systemic antifibrinolytics on the rate of secondary haemorrhage, but not on final visual acuity.
Aylward
G W
GW
Moorfields Eye Hospital, London, UK.
Dunlop
I S
IS
Little
B C
BC
D000933:Antifibrinolytic Agents / Q000627:therapeutic use*; D005131:Eye Injuries / Q000150:complications; D006801:Humans; D006988:Hyphema / Q000188:drug therapy* / Q000209:etiology; D016017:Odds Ratio; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data; D012008:Recurrence; D016896:Treatment Outcome; D014792:Visual Acuity
D000933:Antifibrinolytic Agents