Con: intraoperative myocardial ischemia is not benign.
The principal importance of intraoperative ischemia is its consistent association with adverse outcome. In coronary artery surgery the finding of prebypass ischemia is an important predictor, and postbypass ischemia is a critical predictor of adverse outcome. One in three patients with postbypass ischemia will suffer an adverse outcome in CABG. Furthermore, prevention of postbypass ischemia may improve outcome in CABG. Clearly, intraoperative ischemia in CABG surgery is an ominous sign that should be regarded with the utmost concern by anesthesiologists. In noncardiac surgery, intraoperative ischemia also indicates about a one in three chance of adverse outcome. Although it is less sensitive than postoperative ischemia, it may have superior positive predictive power and specificity. Most importantly, intraoperative monitoring for ischemia is currently available to most patients, whereas extended postoperative monitoring is not. The finding of intraoperative ischemia defines a high-risk group of patients who may merit special monitoring and treatment. To regard intraoperative ischemia as benign would be inconsistent with available information.
Thomson
I R
IR
Department of Anesthesia, St. Boniface General Hospital, Winnipeg, Manitoba, Canada.
D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D001026:Coronary Artery Bypass / Q000009:adverse effects; D003327:Coronary Disease / Q000601:surgery*; D015716:Electrocardiography, Ambulatory; D005544:Forecasting; D006801:Humans; D007431:Intraoperative Complications; D016343:Monitoring, Intraoperative; D017202:Myocardial Ischemia / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D016896:Treatment Outcome