title: Bacteriostatic and bactericidal activities of paromomycin against Mycobacterium avium complex isolates.
abstract: The MICs and MBCs of paromomycin for 32 Mycobacterium avium complex (MAC) strains isolated from patients with the acquired immunodeficiency syndrome were determined by a radiometric broth dilution method. The MICs for the majority of strains were either 8 or 16 mg/L and the MBCs were four- to eight-fold higher. Paromomycin merits further evaluation as oral prophylaxis against disseminated MAC infection.
authors: Department of Clinical Microbiology, General Hospital Umberto I., Torrette, Ancona, Italy.
authors: C
authors: C
authors: Piersimoni
authors: S
authors: S
authors: Bornigia
authors: G
authors: G
authors: De Sio
authors: G
authors: G
authors: Scalise
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D015269:Mycobacterium avium Complex / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D010303:Paromomycin / Q000494:pharmacology*
chemical_list: D010303:Paromomycin