Bilateral cerebral mediofrontal hypoactivity in Tc-99m HMPAO SPECT imaging.
Fifteen patients who had bilateral mediofrontal hypoactivity and 30 control subjects without this SPECT anomaly underwent Tc-99m HMPAO brain SPECT imaging. Bilateral mediofrontal hypoactivity was found in various neurologic disorders, including subcortical arteriosclerotic encephalopathy, lacunar state, chronic alcoholism, progressive nonvascular dementia, carbon monoxide poisoning, and diabetes mellitus. This SPECT abnormality was, however, specifically associated with three clinical signs: motor disabilities predominating in the lower limbs, urinary incontinence, and akinetic mutism.
Denays
R
R
Department of Neurology, St.-Pierre Hospital, Brussels, Belgium.
Tondeur
M
M
Noël
P
P
Ham
H R
HR
D000405:Akinetic Mutism / Q000209:etiology; D000437:Alcoholism / Q000150:complications / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation / Q000502:physiology; D002561:Cerebrovascular Disorders / Q000150:complications / Q000000981:diagnostic imaging; D003704:Dementia / Q000150:complications / Q000000981:diagnostic imaging; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014549:Urinary Incontinence / Q000209:etiology
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime