title: Ultrastructural and immunocytochemical features of a case of neuroendocrine carcinoma developing in a prior ileostomy site.
abstract: A patient who developed a mixed neuroendocrine carcinoma and adenocarcinoma at the site of a previous long-standing ileostomy is reported. The neuroendocrine features are documented by both ultrastructural and immunocytochemical findings. Carcinoma arising in an ileostomy site is rare but has been recorded in patients with long-standing ileostomies after colectomy for chronic inflammatory bowel disease, as in this patient. Neuroendocrine carcinoma developing in this setting apparently has not been described before, however.
authors: Department of Pathology and Laboratory Medicine, University of Alabama at Birmingham.
authors: C M
authors: CM
authors: Listinsky
authors: N B
authors: NB
authors: Halpern
authors: R B
authors: RB
authors: Workman
authors: G A
authors: GA
authors: Herrera
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000209:etiology / Q000473:pathology* / Q000648:ultrastructure; D018278:Carcinoma, Neuroendocrine / Q000737:chemistry / Q000209:etiology / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007078:Ileal Neoplasms / Q000737:chemistry / Q000209:etiology / Q000473:pathology* / Q000648:ultrastructure; D007081:Ileostomy / Q000009:adverse effects*; D007124:Immunoenzyme Techniques; D015212:Inflammatory Bowel Diseases / Q000601:surgery; D008297:Male; D008875:Middle Aged