[Intervention and clinical aspects combined with endovascular irradiation of intimal hyperplasia of the vascular system].
After implantation of stents in femoropopliteal arteries we found restenosis or occlusions by intimal hyperplasia in up to 40% especially in the hunter's channel. Repeated balloon angioplasty and prophylactic endovascular radiotherapy with a surface dose of 12 Gy in the vessel wall using an iridium 192 source in the same investigational session is a new technique to reduce or eliminate further recurrence. All 18 patients had developed recurrent stenoses or occlusions 6-8 months after original stent implantations. The patients have not redeveloped recurrent obstructions after this treatment, which up to date showed no short term or long term complications. We conclude that the encouraging results of this pilot study justify further randomized trials.
Liermann
D
D
Abteilung für Röntgendiagnostik, Universität Frankfurt am Main.
Berkefeld
J
J
Herrmann
G
G
Schopohl
B
B
Strassmann
G
G
Adamitz
I
I
Kollath
J
J
D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon / Q000295:instrumentation*; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*; D001918:Brachytherapy / Q000295:instrumentation*; D005260:Female; D005352:Fibromuscular Dysplasia / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000473:pathology / Q000528:radiation effects; D011859:Radiography; D011879:Radiotherapy Dosage; D012008:Recurrence; D015607:Stents
Intervention und Klinik im Zusammenhang mit der endovaskulären Radiatio intimaler Hyperplasien im Gefässsystem.