[Effect of different follicle puncture methods on hormone homeostasis in the woman. Studies within the scope of an in vitro fertilization-embryo transfer program].
Different methods for follicular puncture which were used in an in vitro fertilization-embryo transfer program have been analyzed in order to determine their influence on plasma levels of estradiol, progesterone, prolactin and beta-endorphins. Thirty-eight patients awaiting oocyte aspiration were randomized into a laparoscopic (n = 20) and an ultrasound-guided oocyte aspiration group (n = 18). No differences were observed as far as estradiol and progesterone levels and embryo transfer rates were concerned. When using the laparoscopic technique, prolactin levels were found to be elevated 1.5 times in comparison with the ultrasound-guided aspiration procedure, which is highly significant (p < 0.001). Also, beta-endorphins peaked at a significantly higher level during laparoscopy (27.8 vs. 20.7 mol/l, p < 0.001). The enhanced prolactin and beta-endorphin levels reflect an increased stress response during laparoscopy. With respect to less trauma and shorter duration of the procedure, we now perform the sonographically guided transvaginal aspiration technique in our program almost exclusively.
Nitsch
C D
CD
Universitäts-Frauenklinik Ulm, Deutschland.
Sterzik
K
K
Korda
P
P
Sasse
V
V
Rosenbusch
B
B
Marx
T
T
Traub
E
E
Kreienberg
R
R
D000328:Adult; D001707:Biopsy, Needle / Q000379:methods; D004624:Embryo Transfer; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D006080:Ovarian Follicle / Q000473:pathology; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D011677:Punctures / Q000379:methods; D014463:Ultrasonography / Q000379:methods; D001615:beta-Endorphin / Q000097:blood
D012739:Gonadal Steroid Hormones; D011374:Progesterone; D004958:Estradiol; D001615:beta-Endorphin; D011388:Prolactin
Der Einfluss unterschiedlicher Follikelpunktionsmethoden auf den Hormonhaushalt der Frau. Untersuchungen im Rahmen eines In-vitro-Fertilisation-Embryotransfer-Programmes.