Gene therapy for muscle diseases.
Duchenne muscular dystrophy involves progressive degeneration of the skeletal and cardiac muscles, resulting in premature death. A number of methods are currently being developed for the treatment of Duchenne muscular dystrophy and other neuromuscular disorders. A number of the viral vector systems, myoblast transfer, and direct injection techniques that are currently under investigation for the treatment of neuromuscular disorders are reviewed here.
Coovert
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DD
Ohio State University, Columbus.
Burghes
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AH
D016189:Dystrophin / Q000235:genetics; D005544:Forecasting; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D006801:Humans; D009136:Muscular Dystrophies / Q000145:classification / Q000235:genetics / Q000628:therapy; D009468:Neuromuscular Diseases / Q000145:classification / Q000235:genetics* / Q000628:therapy; D014162:Transfection / Q000235:genetics
D016189:Dystrophin