Corticotropin-releasing hormone enables weaning from ventilator in a neurosurgical patient under long-term controlled mechanical respiratory support.
A patient with recurrent hemorrhage into the posterior fossa leading to loss of central respiratory drive is described. Repeated i.v. application of corticotropin-releasing hormone over a period of 24 days enabled weaning from long-term controlled mechanical ventilation by reinstitution and maintenance of spontaneous respiration.
Luyken
C
C
Department of Neurosurgery, University of Cologne.
Hildebrandt
G
G
Brinker
G
G
Börner
U
U
Klug
N
N
D000328:Adult; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000601:surgery*; D003346:Corticotropin-Releasing Hormone / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D007262:Infusions, Intravenous; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000188:drug therapy*; D012008:Recurrence; D012086:Reoperation; D012133:Respiratory Paralysis / Q000188:drug therapy*; D015300:Ventilator Weaning
D003346:Corticotropin-Releasing Hormone