The fibulin-1 gene (FBLN1) is located on human chromosome 22 and on mouse chromosome 15.
Fibulin-1 is a calcium-binding glycoprotein present in the extracellular matrix and in the serum. The gene coding for fibulin-1 (FBLN1) was located by in situ hybridization of 3H-labeled cDNA probes to human and mouse metaphase chromosomes. The gene was assigned to the q13.2-q13.3 region of human chromosome 22 and to the E-F band of mouse chromosome 15. This finding extends the evolutionary conservation between human chromosome 22 and mouse chromosome 15.
Mattei
M G
MG
U-242 INSERM, Hôpital d'Enfants de la Timone, Marseille, France.
Pan
T C
TC
Zhang
R Z
RZ
Timpl
R
R
Chu
M L
ML
D000818:Animals; D002135:Calcium-Binding Proteins / Q000235:genetics*; D002478:Cells, Cultured; D002874:Chromosome Mapping; D002892:Chromosomes, Human, Pair 22; D005796:Genes; D006801:Humans; D017403:In Situ Hybridization; D008214:Lymphocytes / Q000648:ultrastructure; D051379:Mice / Q000235:genetics*; D009363:Neoplasm Proteins / Q000235:genetics*
D002135:Calcium-Binding Proteins; D009363:Neoplasm Proteins; C060820:fibulin