[Tardive dystonia. A rare neuroleptic-induced disease picture].
This paper reports on a case of spasmodic torticollis after longterm treatment with neuroleptics. This form of dystonia is called tardive dystonia to distinguish it from tardive dyskinesia. Its pathophysiology is unknown. Pathological changes are described in the basal ganglia. Increased signal was found on magnetic resonance imaging on both sides of the basal ganglia reflecting structural lesions. These structural changes, together with neuroleptic medication, represent predisposing factors for the manifestation of tardive dystonia.
Assion
H J
HJ
Psychiatrische Universitätsklinik, Bonn.
Heinemann
F
F
D001479:Basal Ganglia / Q000473:pathology; D001480:Basal Ganglia Diseases / Q000139:chemically induced* / Q000175:diagnosis; D004359:Drug Therapy, Combination; D004421:Dystonia / Q000139:chemically induced* / Q000175:diagnosis; D004576:Electromyography / Q000187:drug effects; D005260:Female; D005475:Flupenthixol / Q000009:adverse effects* / Q000627:therapeutic use; D006220:Haloperidol / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology; D014103:Torticollis / Q000139:chemically induced / Q000175:diagnosis
D005475:Flupenthixol; D006220:Haloperidol
Tardive Dystonie. Ein seltenes neuroleptikainduziertes Krankheitsbild.