Primary lymphoplasmacytic lymphoma of the liver associated with a serum monoclonal peak of IgG kappa.
We report a case of primary lymphoma of the liver successfully treated by major liver resection. The tumor exhibited the immunohistological features of a B-cell low-grade lymphoma of the lymphoplasmacytic type. Tumoral plasmacytic cells showed cytoplasmic-positive staining for IgG and kappa light chains. In addition, we detected a serum monoclonal peak of IgG kappa, a finding that has not been reported previously. Clinical, pathological, and immunohistochemical data from the literature are reviewed.
Borgonovo
G
G
Service de Chirurgie, Hopital Antoine Béclère, Clamart, France.
d'Oiron
R
R
Amato
A
A
Léger-Ravet
M B
MB
Iseni
M C
MC
Smadja
C
C
Lemaigre
G
G
Franco
D
D
D000328:Adult; D000911:Antibodies, Monoclonal / Q000097:blood*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007145:Immunoglobulin kappa-Chains / Q000097:blood*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology*; D008113:Liver Neoplasms / Q000276:immunology*; D008297:Male
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains