A quick silver method for senile plaques and neurofibrillary tangles in paraffin sections.
A new silver method for senile plaques and neurofibrillary tangles (NFT) in paraffin sections is presented. This new technique is rapid in execution (15 min) and reveals senile plaques of all morphological types as well as NFT. The silver staining is spatially congruent with immunocytochemical staining for the beta-amyloid peptide (A beta) in adjacent sections.
Hedreen
J C
JC
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205-2196.
Raskin
L S
LS
Price
D L
DL
D000544:Alzheimer Disease / Q000473:pathology*; D006801:Humans; D016874:Neurofibrillary Tangles / Q000737:chemistry*; D016612:Paraffin Embedding; D016622:Silver Staining / Q000379:methods*; D013997:Time Factors