Clinical application of spontaneous red blood cell labeling with Tc-99m sodium pertechnetate.
Red blood cells (RBC) may be labeled with Tc-99m after Tc-99m sodium pertechnetate is injected in the presence of a reducing agent, such as stannous chloride. Thus, spontaneous RBC labeling with Tc-99m is expected to be seen in patients with a high plasma concentration of tin. Spontaneous RBC labeling with Tc-99m was obtained in a 73-year-old woman who was clinically diagnosed with tin intoxication and proved to have a high concentration of plasma tin. The RBC labeling rate was calculated as 96% with blood sampling. Spontaneous RBC labeling with Tc-99m is a very simple method for proving a high plasma tin concentration and is adaptable to clinical diagnosis.
Kaminaga
T
T
Division of Tracer Kinetics, Osaka University Medical School, Japan.
Nishimura
T
T
Hayashida
K
K
Ishida
Y
Y
Hiroki
M
M
D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D004912:Erythrocytes; D005260:Female; D006801:Humans; D007553:Isotope Labeling; D011859:Radiography; D013670:Sodium Pertechnetate Tc 99m; D014001:Tin / Q000097:blood* / Q000506:poisoning*; D015899:Tomography, Emission-Computed, Single-Photon
D014001:Tin; D013670:Sodium Pertechnetate Tc 99m