Dyskinesia in mentally handicapped women: relationship to level of handicap, age and neuroleptic exposure.
The prevalence of dyskinesia in a randomly selected set of 61 mentally handicapped women with a range of diagnoses, levels of IQ and exposure to neuroleptics was assessed using the Abnormal Involuntary Movements Scale (AIMS). Overall, 64% of patients had dyskinesia on the AIMS. There was no correlation with neuroleptic exposure, although 43% of patients had been significantly exposed. There was no correlation between the presence of dyskinesia and the original handicapping diagnosis, and there was no increase in dyskinesia as the patients age increased. There was a significant increase in dyskinesia as IQ fell. This study backs the contention that there is a close association between cognitive impairment and movement disorder.
Farren
C K
CK
Department of Psychiatry, Eastern Health Board, Dublin, Ireland.
Dinan
T G
TG
D000328:Adult; D000367:Age Factors; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004409:Dyskinesia, Drug-Induced / Q000209:etiology* / Q000523:psychology; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy* / Q000523:psychology; D007360:Intelligence; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D012307:Risk Factors
D014150:Antipsychotic Agents