Creatine kinase elevations with clozapine.
We describe a patient with marked elevations of creatine kinase following institution of clozapine treatment. The enzyme levels promptly subsided with discontinuation of clozapine. The clinical features did not meet any of the published criteria for neuroleptic malignant syndrome.
Keshavan
M S
MS
Schizophrenia Inpatient Unit, University of Pittsburgh, PA.
Stecker
J
J
Kambhampati
R K
RK
D000328:Adult; D003024:Clozapine / Q000009:adverse effects* / Q000627:therapeutic use; D003402:Creatine Kinase / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000201:enzymology; D012563:Schizophrenia, Paranoid / Q000175:diagnosis / Q000188:drug therapy* / Q000201:enzymology / Q000523:psychology
D003402:Creatine Kinase; D003024:Clozapine