[Vasodilator nerves].
In addition to sympathetic vasoconstrictor nerves, nonadrenergic, noncholinergic vasodilator nerves control the vascular tone. In cerebral arteries of various species of animals, nitric oxide (NO) is a potential candidate for the vasodilator transmitter. In rat mesenteric arterioles, calcitonin gene-related peptide (CGRP) functions as a transmitter. In guinea pig mesenteric arteries, multiple transmitters including NO and CGRP mediate the vasodilator response. The physiological and pathophysiological significance of vasodilator nerves is to be determined.
Saito
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A
Department of Pharmacology, University of Tsukuba, Ibaraki, Japan.
D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000502:physiology; D002536:Cerebral Arteries / Q000294:innervation / Q000502:physiology; D008638:Mesenteric Arteries / Q000294:innervation / Q000502:physiology; D018377:Neurotransmitter Agents / Q000502:physiology; D009569:Nitric Oxide / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology*; D014664:Vasodilation
D018377:Neurotransmitter Agents; D009569:Nitric Oxide; D015740:Calcitonin Gene-Related Peptide