The respiratory system of Kluyveromyces lactis escapes from HAP2 control.
A functional homolog of the Saccharomyces cerevisiae HAP2 gene, coding for one element of a transcriptional activator complex, was cloned from the yeast Kluyveromyces lactis and its nucleotide sequence was determined. Inactivation of the gene had no significant effect on respiration-dependent growth, suggesting that the HAP2/3/4 complex has no major control over the formation of the mitochondrial respiratory system in K. lactis.
Nguyen
C
C
Institut de Génetique et Microbiologie (CNRS URA1354) Université Paris XI, Orsay, France.
Bolotin-Fukuhara
M
M
Wésolowski-Louvel
M
M
Fukuhara
H
H
D000595:Amino Acid Sequence; D023081:CCAAT-Binding Factor; D015825:Chromosomes, Fungal; D003001:Cloning, Molecular; D005656:Fungal Proteins / Q000096:biosynthesis / Q000235:genetics*; D018628:Gene Dosage; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal / Q000235:genetics; D007716:Kluyveromyces / Q000235:genetics* / Q000502:physiology; D008928:Mitochondria / Q000235:genetics* / Q000502:physiology; D008969:Molecular Sequence Data; D016296:Mutagenesis; D010101:Oxygen Consumption / Q000235:genetics*; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000096:biosynthesis / Q000235:genetics*
D023081:CCAAT-Binding Factor; D005656:Fungal Proteins; D014157:Transcription Factors