Interactions of phenoxyl radical of antitumor drug, etoposide, with reductants in solution and in cell and nuclear homogenates: electron spin resonance and high-performance liquid chromatography.
Gantchev
T G
TG
Department of Nuclear Medicine and Radiobiology, University of Sherbrooke, Québec, Canada.
van Lier
J E
JE
Stoyanovsky
D A
DA
Yalowich
J C
JC
Kagan
V E
VE
D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000494:pharmacology; D001391:Azo Compounds; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods; D005047:Etoposide / Q000737:chemistry* / Q000494:pharmacology*; D005609:Free Radicals; D005978:Glutathione / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D004915:Leukemia, Erythroblastic, Acute; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000378:metabolism; D010636:Phenols; D014407:Tumor Cells, Cultured
D000975:Antioxidants; D001391:Azo Compounds; D005609:Free Radicals; D010636:Phenols; C042329:phenoxy radical; D005047:Etoposide; D014442:Monophenol Monooxygenase; D005978:Glutathione; D001205:Ascorbic Acid