Evaluation of PGE2 gel for cervical ripening and induction of labour.
In a prospective study a single dose PGE2 gel 0.5 mg was given in 97 Low Bishop Score subjects, 12 hrs prior to indicated oxytocin or PGE2 tab induction for cervical ripening. Analysis of 97 subjects shows that it is very highly effective. 56 primi and 21 multi delivered spontaneously with gel administration only while 4 primi and 2 multi delivered vaginally following oxytocin and 3 more cases delivered vaginally following PGE2 tab administration and fewer caesarian section (11) were performed. The endo cervical administration of PGE2 was well tolerated and systemic PGE2 effects were minimal.
Veena
Department of Obstetrics & Gynaecology, Jawaharlal Nehru Medical College, Aligarh Muslim University.
Saxena
K
K
Singhal
K C
KC
D000284:Administration, Oral; D002584:Cervix Uteri / Q000187:drug effects*; D002585:Cesarean Section; D015232:Dinoprostone / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005782:Gels; D006801:Humans; D007745:Labor Onset / Q000187:drug effects*; D007751:Labor, Induced; D010121:Oxytocin / Q000494:pharmacology; D010298:Parity; D011247:Pregnancy; D011446:Prospective Studies
D005782:Gels; D010121:Oxytocin; D015232:Dinoprostone