Dorsolateral prostatic phosphomonoesterases and adenosine triphosphatases in hypo- and hyperthyroid rats.
Specific activities of phosphomonoesterases (acid and alkaline phosphatases) and adenosine triphosphatases (Mg2+, Ca2+ and Na+/K+ dependent ATPases) of dorsolateral prostate were studied in albino rats, under altered thyroid hormone status. Thyroidectomy induced hypothyroidism and thyroxine administered hyperthyroidism (25 micrograms/100 g body wt/day for 60 days, im) showed no impact on the activity of acid phosphatase. Three fold decrease in the activity of alkaline phosphatase was observed in hyperthyroid group. Ca2+ and Mg2+ dependent ATPases were significantly decreased in hypo- and hyperthyroid status whereas Na+/K+ ATPase was decreased in hyperthyroidism and showed an opposite trend in hypothyroid group.
Sidharthan
V
V
Department of Endocrinology, Dr A L M P G Institute of Basic Medical Sciences, University of Madras, Taramani, India.
Rose
P J
PJ
Rajalingam
R
R
Udhayakumar
R C
RC
Aruldhas
M M
MM
Govindarajulu
P
P
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D006980:Hyperthyroidism / Q000201:enzymology*; D007037:Hypothyroidism / Q000201:enzymology*; D008297:Male; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D011467:Prostate / Q000201:enzymology*; D051381:Rats; D017208:Rats, Wistar
D010744:Phosphoric Monoester Hydrolases; D000251:Adenosine Triphosphatases