In pursuit of a molecular mechanism for adaptive mutation.
An unexpected way of making mutations in bacteria has challenged concepts of the genetic mechanisms behind evolution for the past 6 years. Work on the molecular mechanism of these so called "adaptive" mutations is rapidly revealing a surprising and novel molecular mechanism, and it is altering our understanding of how mutations form in nondividing cells.
Rosenberg
S M
SM
Department of Biochemistry, Faculty of Medicine, University of Alberta, Edmonton, Canada.
D000222:Adaptation, Physiological / Q000235:genetics*; D001419:Bacteria / Q000235:genetics*; D005075:Biological Evolution; D008957:Models, Genetic; D009154:Mutation / Q000502:physiology*; D011995:Recombination, Genetic