title: [Antimycobacterial acting carbazole derivatives].
abstract: Carbazoles are synthesized and tested for antimycobacterial properties (M. tuberculosis H 37 Ra, Middlebrook-7H9-broth). The different antimycobacterial properties of diastereomeres are examined using compounds 32 and 33, those of a racemic compound and the (+)-enantiomer are tested with (+/-)-12/(+)-12 and (+/-)-5/(+)-5, respectively. (+)-12 is prepared by enantioselective synthesis.
authors: Institut für Pharmazie, Universität Regensburg.
authors: S
authors: S
authors: Mahboobi
authors: S
authors: S
authors: Kuhr
authors: W
authors: W
authors: Meindl
mesh_terms: D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002227:Carbazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D009161:Mycobacterium / Q000187:drug effects*; D009169:Mycobacterium tuberculosis / Q000187:drug effects
chemical_list: D000995:Antitubercular Agents; D002227:Carbazoles
vernacular_title: Antimycobakteriell wirksame Carbazolderivate.