title: Inhibitory effect of dairy products on the mutagenicities of chemicals and dietary mutagens.
abstract: The antimutagenic effects of uninoculated milk and milks cultured with Bifidobacterium or Lactobacillus strains towards the mutagenicity induced by two direct mutagens, 4-nitroquinoline N-oxide and 2-nitrofluorene, and three dietary indirect mutagens, aflatoxin B1, benzo(a)pyrene and quercetin, were investigated using the in vitro Salmonella typhimurium test. Each cultured milk sample and control milk had a significant antimutagenic effect, to an extent varying with the mutagen used. Uninoculated milk had a greater inhibitory effect than cultured milks towards dietary indirect mutagens.
authors: Laboratoire de Toxicologie Alimentaire, Université de Bordeaux I, Talence, France.
authors: P
authors: P
authors: Cassand
authors: H
authors: H
authors: Abdelali
authors: C
authors: C
authors: Bouley
authors: G
authors: G
authors: Denariaz
authors: J F
authors: JF
authors: Narbonne
mesh_terms: D015112:4-Nitroquinoline-1-oxide; D016604:Aflatoxin B1 / Q000037:antagonists & inhibitors; D000818:Animals; D016587:Antimutagenic Agents; D001564:Benzo(a)pyrene / Q000037:antagonists & inhibitors; D001644:Bifidobacterium / Q000502:physiology*; D002417:Cattle; D005260:Female; D005449:Fluorenes / Q000037:antagonists & inhibitors; D066298:In Vitro Techniques; D007778:Lactobacillus / Q000502:physiology*; D008297:Male; D008892:Milk / Q000502:physiology*; D009152:Mutagenicity Tests / Q000662:veterinary; D011794:Quercetin / Q000037:antagonists & inhibitors; D051381:Rats; D017207:Rats, Sprague-Dawley; D012486:Salmonella typhimurium / Q000187:drug effects
chemical_list: D016587:Antimutagenic Agents; D005449:Fluorenes; C019499:2-nitrofluorene; D001564:Benzo(a)pyrene; D015112:4-Nitroquinoline-1-oxide; D011794:Quercetin; D016604:Aflatoxin B1