[The role of percutaneous renal biopsy in kidney transplant].
Percutaneous renal biopsy (PRB) is an useful tool for diagnostic and therapeutic orientation in renal transplantation. PURPOSE--To evaluate the current role of PRB in post-transplant acute renal dysfunction (ARD) of renal allografts. METHODS--Sixty-five renal transplant patients were submitted to 95 valid renal biopsies with no major complications. RESULTS--There was disagreement between the clinical and the pathological diagnosis in 28 occasions (29.5%). In 36 cases (37.9%) the results of the pathological examination led to a modification in patient's management. These modifications were most commonly the avoidance or witholding of a steroid pulse (8 cases); nephrectomy of the renal allograft (8 cases); witholding or decrease of cyclosporine dosage (6 cases); giving a steroid pulse (5 cases) and giving antibiotics to treat acute pyelonephritis in 4 cases. The use of kidneys from cadaveric donors was significantly associated with an increased number of biopsies (p < 0.05). CONCLUSION--These results demonstrate that even though several less invasive procedures are currently employed, renal biopsy is still an indispensable method to the management of ARD in renal transplant patients.
Manfro
R C
RC
Unidade de Transplante Renal do Hospital de Clínicas de Porto Alegre da Universidade Federal do Rio Grande do Sul.
Lee
J Y
JY
Lewgoy
J
J
Edelweiss
M I
MI
Gonçalves
L F
LF
Prompt
C A
CA
D000328:Adult; D001707:Biopsy, Needle; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000473:pathology*; D016030:Kidney Transplantation / Q000473:pathology*; D008297:Male; D012189:Retrospective Studies
O papel da biópsia renal percutânea no transplante renal.