title: Rapid normalization of visual evoked potentials by picoTesla range magnetic fields in chronic progressive multiple sclerosis.
abstract: This communication concerns a 55 year old woman with a 5 year history of chronic progressive multiple sclerosis (MS) in whom a single external application of extremely low magnetic fields (MF) (7.5 picoTesla; 5 Hz frequency) of 20 minutes duration resulted in a rapid improvement in symptoms including vision, cerebellar symptomatology (ataxia and dysarthria), bladder functions, mood, sleep, cognitive functions and fatigue. Improvement in the patient's symptoms was associated with normalization of the pretreatment abnormal visual evoked potential (VEP) latencies within 24 hours after magnetic treatment. The rapid normalization of the VEP latencies suggests that recovery did not occur as a result of remyelination but probably was related to enhancement of neurotransmitter functions. MF have been shown to alter cellular calcium metabolism which may facilitate axonal conduction in demyelinating plaques. Furthermore, as MF affects the release of the pineal gland's principal hormone, melatonin, which influences the release of monoamines, it is also hypothesized that the effects of picoTesla MF in MS are partly mediated by the pineal gland which has recently been implicated in the pathogenesis of MS (Sandyk, 1992 a).
authors: NeuroCommunication Research Laboratories, Danbury, CT 06811.
authors: R
authors: R
authors: Sandyk
mesh_terms: D001921:Brain / Q000503:physiopathology; D002908:Chronic Disease; D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008280:Magnetics / Q000627:therapeutic use*; D008550:Melatonin / Q000096:biosynthesis; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology / Q000628:therapy*; D010870:Pineal Gland / Q000378:metabolism; D012701:Serotonin / Q000502:physiology; D009435:Synaptic Transmission; D016896:Treatment Outcome
chemical_list: D012701:Serotonin; D008550:Melatonin