[Thromboembolic events in heparin-induced thrombocytopenia].
Thrombocytopenia following heparin treatment appears in 5% of patients so treated. In 20% of such patients paradoxical thromboembolic phenomena may be associated with the thrombocytopenia. This process is most probably mediated via an antibody reaction against a heparin-platelet complex. We present a 70-year-old woman with recurrent episodes of lower extremity thrombophlebitis associated with thrombocytopenia following treatment with heparin for pulmonary embolism.
Amital
H
H
Dept. of Medicine B, Chaim Sheba Medical Center, Tel Hashomer.
Shoenfeld
Y
Y
D000368:Aged; D005260:Female; D006493:Heparin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D011655:Pulmonary Embolism / Q000188:drug therapy*; D013921:Thrombocytopenia / Q000139:chemically induced*; D013924:Thrombophlebitis / Q000139:chemically induced*
D006493:Heparin