title: Role of viscous guar gums in lowering the glycemic response after a solid meal.
abstract: The aim of the present study was to investigate how guar gum viscosity acts on starch digestion and glucose absorption in humans. Six healthy subjects received a mixed diet composed of 60.4% carbohydrate in the form of maize glucose or pregelatinized starch, to which was added 5.6% low- or high-viscosity guar gums. Meals were ingested or instilled in the duodenum and postprandial insulin and glucose responses were monitored for 3 h. Infusion of meals containing glucose showed that the delay in the diffusion rate to the duodenal mucosa due to bolus viscosity was not significant. Infusion of meals containing starch showed that a decrease in the digestion rate of starch in the upper small intestine accounted for part of the effect of viscosity on glycemic response, whereas the main effect of guar gum was apparently to slow gastric emptying.
authors: Institut National de la Recherche Agronomique, Nantes, France.
authors: C J
authors: CJ
authors: Leclère
authors: M
authors: M
authors: Champ
authors: J
authors: J
authors: Boillot
authors: G
authors: G
authors: Guille
authors: G
authors: G
authors: Lecannu
authors: C
authors: C
authors: Molis
authors: F
authors: F
authors: Bornet
authors: M
authors: M
authors: Krempf
authors: J
authors: J
authors: Delort-Laval
authors: J P
authors: JP
authors: Galmiche
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001944:Breath Tests; D002245:Carbon Dioxide / Q000032:analysis; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000378:metabolism; D004043:Dietary Fiber; D005260:Female; D005685:Galactans / Q000008:administration & dosage / Q000494:pharmacology*; D005746:Gastric Emptying / Q000187:drug effects; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D007328:Insulin / Q000097:blood; D007408:Intestinal Absorption / Q000187:drug effects; D008297:Male; D008351:Mannans / Q000008:administration & dosage / Q000494:pharmacology*; D053149:Plant Gums; D013213:Starch / Q000378:metabolism*; D014783:Viscosity
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D004043:Dietary Fiber; D005685:Galactans; D007328:Insulin; D008351:Mannans; D053149:Plant Gums; D002245:Carbon Dioxide; D013213:Starch; C007894:guar gum; D005947:Glucose