title: T2-weighted breath-hold MR imaging of the liver at 1.5 T: results with a three-dimensional steady-state free precession sequence in 87 patients.
abstract: OBJECTIVE
  To evaluate a fast three-dimensional (3D) sequence that permits the acquisition of 16 T2-weighted images within a 29-second breath hold for magnetic resonance (MR) imaging of the liver.
  
  
  METHODS
  Eighty-seven patients with focal liver lesions were examined at 1.5 T by using a 3D reversed fast imaging with steady-state precession (PSIF) sequence at flip angles of 15 degrees, 30 degrees, and 70 degrees and a T2-weighted spin-echo (SE) sequence. Quantitative and qualitative image analysis was performed.
  
  
  RESULTS
  Contrast and signal difference-to-noise ratios were 56% and 33% (liver-spleen) and 76% and 68% (liver-tumor), respectively, with the 3D-PSIF sequence compared with the T2-weighted SE sequence. With 3D-PSIF, overall image quality was poorer than that of the T2-weighted SE sequence at flip angles of 15 degrees but was similar at 30 degrees and 70 degrees. At low flip angles (15 degrees and 30 degrees) all lesion types were hyperintense. At a flip angle of 70 degrees, it was predominantly cysts and hemangiomas that showed high signal intensity. With the 3D-PSIF sequence, intrahepatic vessels are void of signal and can be better distinguished from small liver lesions compared with the flow-compensated T2-weighted SE sequence.
  
  
  CONCLUSIONS
  The fast 3D-PSIF sequence is a valuable addition to MR imaging of the liver.
authors: Department of Radiology, Klinikum Benjamin Franklin, Freie Universität Berlin, Germany.
authors: M
authors: M
authors: Taupitz
authors: A
authors: A
authors: Speidel
authors: B
authors: B
authors: Hamm
authors: M
authors: M
authors: Deimling
authors: M
authors: M
authors: Reichel
authors: A
authors: A
authors: Bock
authors: K J
authors: KJ
authors: Wolf
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis; D005260:Female; D006391:Hemangioma / Q000175:diagnosis; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis*; D008113:Liver Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013154:Spleen / Q000473:pathology