title: Changes in cardiovascular activity during an increase in biliary tract pressure in rabbits.
abstract: In order to study the mechanism of decreased blood pressure caused by an acute increase in biliary tract pressure, we observed house rabbit model of self-made caecus for changes in cardiovascular function when biliary tract pressure was increased. It was found that both the blood pressure and cardiac output evidently decreased (P < 0.05) parallelly, and the systolic pressure decreased more markedly than diastolic pressure. At the same time there was fluctuation in heart rate and in central venous pressure; but there was no significant difference between them (P > 0.05), suggesting that in the absence of infective agents, the increased biliary tract pressure can bring about a decrease in cardiac output, which is an important factor contributing to an early blood pressure decrease in acute cholangitis of severe type (ACST).
authors: Department of Surgery, Union Hospital, Tongji Medical University, Wuhan.
authors: Q C
authors: QC
authors: Zheng
authors: J Y
authors: JY
authors: Ye
authors: Y H
authors: YH
authors: Hu
authors: M L
authors: ML
authors: Guan
authors: D X
authors: DX
authors: Wang
mesh_terms: D000818:Animals; D001659:Biliary Tract / Q000502:physiology*; D002496:Central Venous Pressure; D002761:Cholangitis / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics; D008297:Male; D011312:Pressure; D011817:Rabbits; D013153:Splanchnic Nerves / Q000502:physiology