Bilateral asymmetry of cerebral blood velocity in cluster headache.
In this study, 69 episodic cluster headache (CH) patients (40 in the active phase, 29 in remission period) underwent a complete TCD examination in order to verify the relationship between cerebral blood velocities (CBVs) and the clinical profile of the disease. Fifteen patients were examined during both phases, while 7 were monitored during a spontaneous attack. Sixty-three healthy sex and age-matched controls were also studied. We measured widespread, asymmetric CBV activation during the active phase, bilaterally in the anterior circulation and also in the posterior circulation. A relative reduction of CBV on the anterior cerebral artery pain side, also during remission, suggests a relationship between local vasodilation and the autonomic symptoms ipsilateral to pain during CH attacks.
Micieli
G
G
Department of Neurology, C. Mondino Foundation, University of Pavia, Italy.
Bosone
D
D
Cavallini
A
A
Rossi
F
F
Pompeo
F
F
Tassorelli
C
C
Nappi
G
G
D000328:Adult; D000704:Analysis of Variance; D001783:Blood Flow Velocity; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003027:Cluster Headache / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D017585:Ultrasonography, Doppler, Transcranial; D014664:Vasodilation; D014666:Vasomotor System