title: Changes in sensitivities of amplitude and frequency curves of the Hodgkin-Huxley system produced by variations of maximal conductances.
abstract: The question of sensitivity of amplitude and frequency curves of the Hodgkin-Huxley system to variations of maximal values of sodium (gNa) and potassium (gK) conductances is considered. Changes in the sensitivity produced by simultaneous changes in gNa and gK values are examined. It has been shown that simultaneous increase of the values of gNa and gK is accompanied by decrease of the sensitivity and, therefore, by improvement of quality of nerve fiber functioning.
authors: Department of Applied Mathematics, Russian Academy of Sciences, St. Petersburg.
authors: Y A
authors: YA
authors: Bedrov
authors: G N
authors: GN
authors: Akoev
authors: O E
authors: OE
authors: Dick
mesh_terms: D000465:Algorithms; D000818:Animals; D004553:Electric Conductivity; D008564:Membrane Potentials; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology; D015221:Potassium Channels / Q000378:metabolism; D015222:Sodium Channels / Q000378:metabolism
chemical_list: D015221:Potassium Channels; D015222:Sodium Channels