Poisoning due to Savlon (cetrimide) liquid.
1. Seven adult cases of deliberate oral exposure to 'Savlon' liquid (chlorhexidine gluconate 0.3%, cetrimide 3%) are presented. 2. In six patients, the symptoms were relatively mild including nausea, vomiting, sore throat and abdominal pain. 3. One patient who had concomitantly taken 'Dettol' liquid was comatose and hypotensive at presentation and was complicated by aspiration pneumonia and adult respiratory distress syndrome (ARDS). She was ventilated for a total of 10 days and was hospitalised for 5 weeks. 4. The data from this study suggest that symptoms associated with Savlon poisoning are usually mild. When aspirated, Savlon together with 'Dettol' liquid can cause ARDS.
Chan
T Y
TY
Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories.
D015746:Abdominal Pain / Q000139:chemically induced; D000293:Adolescent; D000328:Adult; D000368:Aged; D002593:Cetrimonium Compounds / Q000506:poisoning*; D002710:Chlorhexidine / Q000506:poisoning*; D004202:Disinfectants / Q000506:poisoning*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D009325:Nausea / Q000139:chemically induced; D010612:Pharyngitis / Q000139:chemically induced; D011015:Pneumonia, Aspiration / Q000139:chemically induced; D012128:Respiratory Distress Syndrome / Q000139:chemically induced; D014839:Vomiting / Q000139:chemically induced; D014992:Xylenes / Q000506:poisoning*
D002593:Cetrimonium Compounds; D004202:Disinfectants; D004338:Drug Combinations; D014992:Xylenes; C007027:chloroxylenol; C012027:savlon; D002710:Chlorhexidine