title: Effect of chlamydial antibodies on the outcome of in vitro fertilization (IVF) treatment.
abstract: OBJECTIVE
  Our objective was to study the relationship between the presence of Chlamydia trachomatis antibodies and the success of IVF treatment.
  
  
  METHODS
  We evaluated 118 in vitro fertilization and embryo transfer (IVF-ET) treatment cycles from 51 couples with a history of infertility lasting for at least 2 years. All women starting a treatment cycle had their serum chlamydial antibody titers measured by indirect immunofluorescent technique. All patients received similar ovarian stimulation regimens and the oocytes collected were inseminated with similar concentrations of motile sperm. Clinical data from couples where the female partner had C. trachomatis ab titers > or = 40 have been compared with the equivalent data from couples where the female partner had C. trachomatis ab titers < 40.
  
  
  RESULTS
  There was no statistically significant difference between the two groups concerning age, infertility period, oocytes collected, oocytes fertilized, and fertilization rate, and the pregnancy rates were comparable.
  
  
  CONCLUSIONS
  Previous exposure to C. trachomatis did not alter the success rate of IVF-ET.
authors: Department of Obstetrics and Gynecology, Akita University School of Medicine, Japan.
authors: I
authors: I
authors: Tasdemir
authors: M
authors: M
authors: Tasdemir
authors: H
authors: H
authors: Kodama
authors: K
authors: K
authors: Sekine
authors: T
authors: T
authors: Tanaka
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis / Q000276:immunology*; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000628:therapy; D010062:Ovulation Induction; D000292:Pelvic Inflammatory Disease / Q000150:complications / Q000382:microbiology; D011247:Pregnancy; D016896:Treatment Outcome
chemical_list: D000907:Antibodies, Bacterial