Quality of life in osteosarcoma survivors.
Charts of 89 osteosarcoma survivors from Massachusetts General Hospital and The Children's Hospital/Dana Farber Cancer Center, who had received primary treatment more than 1 year previously and had no evidence of disease, were reviewed. Sixty-two patients, mean 12 years from diagnosis, agreed to structured interviews. Rates of psychopathology did not differ significantly from the general population. High distress was noted in 13%. Twenty-three normal progeny had been born postchemotherapy to eight women and the wives of five male patients. One pregnancy was complicated by doxorubicin-induced cardiac toxicity. Only two with previous childhood tumors believed themselves infertile. All felt the effort to save the limb was worthwhile. In most, ongoing pain was mild; phantom pain and neuralgia common. Most survivors were in good mental and physical health with the capacity to bear children.
Greenberg
D B
DB
Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Goorin
A
A
Gebhardt
M C
MC
Gupta
L
L
Stier
N
N
Harmon
D
D
Mankin
H
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000188:drug therapy / Q000523:psychology* / Q000601:surgery; D003131:Combined Modality Therapy; D003863:Depression / Q000209:etiology; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000209:etiology; D012516:Osteosarcoma / Q000188:drug therapy / Q000523:psychology* / Q000601:surgery; D010146:Pain / Q000209:etiology; D010591:Phantom Limb / Q000209:etiology; D011247:Pregnancy; D011788:Quality of Life; D012189:Retrospective Studies; D012917:Social Adjustment; D013315:Stress, Psychological / Q000209:etiology; D013534:Survival / Q000523:psychology