[Clinical significance of cat allergens in adult asthmatics--a study of inhalation provocation tests].
We performed a bronchial provocation tests on 40 adult cat sensitive asthmatics to study the clinical significance of cat allergens. Immediate asthmatic responses (IAR) and/or late asthmatic responses (LAR) were provoked in 29 out of the 40 cases. IAR alone was provoked in 12 cases (30%), LAR alone in 7 cases (17.5%), dual asthmatic responses (DAR) in 10 cases (25%), and no asthmatic response in 11 cases (27.5%). There was no statistical significance in the following parameters among the groups: age, baseline of FEV1.0% and of %MMF, RAST score to cat epithelium and log value of PC20 in acetyl-choline airway hyperreactivity tests. The frequency in contact history with cat was lower in LAR alone (14%) than in the other two groups (78% in DAR, 70% in no asthmatic response). High RAST scores and low PC20 values were more frequent in DAR than in the other groups. Asthmatic responses were found in 15 out of 22 cases (68.2%) with a cat contact history and in 10 out of 16 cases (62.5%) without a contact history. These prevalence rates were the same. We concluded that cat allergens were an important factor not only for child asthmatics but also for adult asthmatics.
Maeda
Y
Y
National Sagamihara Hospital Research Center for Rhemato-Allergology.
Murakami
E
E
Akiyama
K
K
Hasegawa
M
M
Hayakawa
T
T
Kaneko
F
F
Miyamoto
T
T
D000328:Adult; D000485:Allergens / Q000276:immunology*; D000818:Animals; D001249:Asthma / Q000276:immunology*; D001985:Bronchial Provocation Tests; D002415:Cats / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D011852:Radioallergosorbent Test
D000485:Allergens