Juvenile ossifying fibroma. An analysis of 33 cases with emphasis on histopathological aspects.
Juvenile ossifying fibroma (JOF) is a maxillofacial fibro-osseous lesion that may show cell-rich osteoid strands or psammoma-like ossicles. Whether both types are variants of a single entity or different lesions under the same diagnostic label is a subject of debate. This problem was investigated by analyzing a series of 33 patients with lesions having one or both of the above histological appearances. It was concluded that osteoid strands define a unique fibro-osseous lesion but that lesions with psammoma-like ossicles fall within the morphological spectrum of cemento-ossifying fibroma. Therefore the term juvenile ossifying fibroma should be reserved for the lesion with the osteoid strands.
Slootweg
P J
PJ
Department of Pathology, University Hospital, Utrecht, The Netherlands.
Panders
A K
AK
Koopmans
R
R
Nikkels
P G
PG
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D018214:Fibroma, Ossifying / Q000145:classification / Q000473:pathology*; D006801:Humans; D007223:Infant; D007573:Jaw Neoplasms / Q000145:classification / Q000473:pathology*; D008297:Male; D010255:Paranasal Sinus Neoplasms / Q000145:classification / Q000473:pathology*; D009626:Terminology as Topic