Cutaneous infection caused by Curvularia pallescens: a case report and review of the spectrum of disease.
A 75-year-old woman being treated with prednisone and methotrexate had a 5.5 x 2.2 cm ulcer on the leg. A biopsy specimen revealed suppurative, granulomatous dermal inflammation with necrotic areas of septate, branching hyphae containing brown pigment. Cultures grew Curvularia pallescens. Oral ketoconazole therapy was started and the lesion was excised. The site healed after multiple excisions and grafts, and ketoconazole therapy was stopped after 7 months. This is the first reported case of invasive cutaneous infection by C. pallescens.
Berg
D
D
Department of Dermatologic Surgery, University of British Columbia, Vancouver, Canada.
Garcia
J A
JA
Schell
W A
WA
Perfect
J R
JR
Murray
J C
JC
D000368:Aged; D003131:Combined Modality Therapy; D003881:Dermatomycoses / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D007871:Leg Ulcer / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology* / Q000601:surgery; D003904:Mitosporic Fungi / Q000302:isolation & purification
D007654:Ketoconazole