title: Deep central arteriovenous malformations of the brain: the role of endovascular treatment.
abstract: Cerebral deep central arteriovenous malformations (AVMs) are uncommon lesions associated with considerable difficulty in treatment. The authors report a series of 14 deep central AVMs treated by endovascular methods and examine the present role of endovascular treatment. This treatment used alone resulted in complete obliteration of AVMs in approximately 15% of case and reduction in 50% to a size permitting treatment by means of radiosurgery. Reversal of previous neurological signs and symptoms occurred in 35.7% of embolized patients. Overall, nearly 80% of patients had either complete obliteration of the lesion, reduction to a size allowing radiosurgical treatment, or reversal of previous neurological deficits. There were treatment complications in 14.3% of the cases. Endovascular treatment methods may make a significant contribution to the therapy of AVMs that have a particularly poor course and are difficult to treat by other means.
authors: Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia.
authors: R W
authors: RW
authors: Hurst
authors: A
authors: A
authors: Berenstein
authors: M J
authors: MJ
authors: Kupersmith
authors: M
authors: M
authors: Madrid
authors: E S
authors: ES
authors: Flamm
mesh_terms: D000328:Adult; D001479:Basal Ganglia / Q000098:blood supply; D002648:Child; D002941:Circle of Willis; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000601:surgery / Q000628:therapy*; D008297:Male; D016634:Radiosurgery; D013788:Thalamus / Q000098:blood supply