title: Intact survival with transfusion-associated graft-versus-host disease proved by human leukocyte antigen typing of lymphocytes in skin biopsy specimens.
abstract: A transient transfusion-associated graft-versus-host disease occurred in a premature infant of 30 weeks of gestation. We demonstrated donor lymphocytes in a skin biopsy specimen with a two-step immunoperoxidase technique using monoclonal antibodies against human leukocyte antigen determinants specific for the donor. The girl survived and is immunocompetent.
authors: Department of Pediatrics, University Hospital, Münster, Germany.
authors: R
authors: R
authors: Hentschel
authors: E B
authors: EB
authors: Broecker
authors: G
authors: G
authors: Kolde
authors: M
authors: M
authors: Frosch
authors: W
authors: W
authors: Friedrich
authors: W
authors: W
authors: Holzgreve
authors: E
authors: E
authors: Westphal
authors: E
authors: E
authors: Harms
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology; D001706:Biopsy; D001787:Blood Group Incompatibility / Q000175:diagnosis / Q000276:immunology; D001805:Blood Transfusion, Intrauterine / Q000009:adverse effects; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology / Q000276:immunology* / Q000401:mortality; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D007231:Infant, Newborn; D008214:Lymphocytes / Q000276:immunology; D012867:Skin / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D006680:HLA Antigens