Regeneration of hair cells in the vestibulocochlear system of birds and mammals.
Regeneration of hair cells leads to a structural and functional recovery in the mature avian vestibular and auditory sensory epithelia. This regeneration replaces hair cells that have been lost as a result of noise damage, ototoxic drug poisoning, or other trauma. Recent findings suggest that it may be possible to induce a similar mechanism for repair in the vestibular and auditory epithelia of mammals, including humans.
Cotanche
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DA
Department of Anatomy and Neurobiology, Boston University School of Medicine, Massachusetts 02118.
Lee
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KH
D000818:Animals; D001717:Birds; D003051:Cochlea / Q000502:physiology*; D006198:Hair Cells, Auditory / Q000502:physiology*; D006801:Humans; D008322:Mammals; D009416:Nerve Regeneration / Q000502:physiology; D014722:Vestibule, Labyrinth / Q000502:physiology*