Chromosomal localization of four human VH1-like protein-tyrosine phosphatases.
Four human protein-tyrosine phosphatase (PTPase) genes of the VH1-like subclass were cloned by low-stringency screening of a genomic library. These genes were localized to their respective chromosomes by G-banding and fluorescence in situ hybridization. The genes were localized to unique regions of different chromosomes: CL100, a stress-induced PTPase, to 5q35; PAC-1, a mitogen-induced nuclear PTPase, to 2q11;hVH-3 to 10q25; and hVH-4 to 10q11.
Martell
K J
KJ
Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor 48109.
Kwak
S
S
Hakes
D J
DJ
Dixon
J E
JE
Trent
J M
JM
D000595:Amino Acid Sequence; D002874:Chromosome Mapping; D002879:Chromosomes, Human, Pair 10; D002889:Chromosomes, Human, Pair 2; D002895:Chromosomes, Human, Pair 5; D054637:Dual-Specificity Phosphatases; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D017027:Protein Tyrosine Phosphatases / Q000737:chemistry* / Q000235:genetics*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
C489855:dual specificity phosphatase 12; D054637:Dual-Specificity Phosphatases; D017027:Protein Tyrosine Phosphatases