[Idiopathic granulomatous angiitis of the central nervous system].
We diagnosed idiopathic granulomatous angiitis of the central nervous system in a 51-year-old man by leptomeningeal and cortical biopsy. The patient's disease was prolonged, with symptoms recurring over a period of 15 years. Treatment with prednisone and cyclophosphamide produced total remission after a follow-up of 22 months. Computerized tomography was less sensitive and revealed fewer lesions than did magnetic resonance imaging. Angiography was not sensitive and leptomeningeal and cortical biopsy were essential for diagnosis in this patient.
Arpa
J
J
Servicio de Neurología, Hospital La Paz, Universidad Autónoma de Madrid.
Palomo
F
F
Gutiérrez Molina
M
M
Morales
C
C
Alonso de Leciñana
M
M
Barreiro
P
P
D017668:Age of Onset; D001706:Biopsy; D001921:Brain / Q000503:physiopathology*; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000648:ultrastructure; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D014657:Vasculitis / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*
D003520:Cyclophosphamide; D011241:Prednisone
Angeítis granulomatosa idiopática del sistema nervioso central de evolución muy prolongada.