Osteoarthropathia psoriatica of one leg: a manifestation of somatic mosaicism?
A psoriatic osteoarthropathy localized in the left quadrant of a male patient is described. Diagnosis was made on the basis of bone scintigraphy (specific distribution pattern) and histological evaluation of a bone biopsy. There is no indication of psoriasis in the patient's family. Nor is there an association to psoriasis-typical HLA markers. Psoriasis of the skin has not been found. Environmental factors, including a Köbner phenomenon on the skeleton resulting from a trauma 13 years ago (hallux rigidus operation), are discussed in connection with this manifestation. The genetic aspects of this unusual localization are considered.
Holzmann
H
H
Dept. I of the Centre for Dermatology and Venerology, University of Frankfurt, Germany.
Schmitt
M
M
Happle
R
R
Kaltwasser
P
P
Hör
G
G
D015535:Arthritis, Psoriatic / Q000000981:diagnostic imaging* / Q000235:genetics*; D006801:Humans; D007866:Leg / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009030:Mosaicism / Q000235:genetics*; D011877:Radionuclide Imaging