[Changes in bone mineral density of lumbar vertebrae during a six-month interval in African green monkeys (Cercopithecus aethiops)].
Changes in measurements of lumbar vertebrae (L3-L5) during a six-month interval in African green monkeys were demonstrated using dual-energy X-ray absorptiometry (DEXA, DPX-alpha, Lunar, USA). Area, mean width and bone mineral content (BMC) of L3-L5 were measured, and bone mineral density (BMD) was calculated using 62 laboratory-bred and 23 wild animals. Laboratory-bred animals were divided into 4 groups according to their gender and age, and in addition, two groups of wild animals were constructed according to gender. Although no remarkable change in BMD of laboratory-bred animals aged less than two years was observed at a six-month interval, significant decreases in BMD were detected in laboratory-bred animals aged over 6 years as well as in wild animals. Thus, DEXA seems to be useful for investigating the kinetics of BMD in aged animals during a relatively short period such as six-months.
Hiyaoka
A
A
Corporation for Production and Research of Laboratory Primates, National Institute of Health, Ibaraki, Japan.
Yoshida
T
T
Cho
F
F
Yoshikawa
Y
Y
D015502:Absorptiometry, Photon; D000818:Animals; D000830:Animals, Laboratory; D000835:Animals, Wild; D015519:Bone Density; D002522:Chlorocebus aethiops / Q000378:metabolism*; D005260:Female; D008159:Lumbar Vertebrae / Q000378:metabolism*; D008297:Male; D013997:Time Factors