title: Dimerisation of levonorgestrel in solid state ultraviolet light irradiation.
abstract: UV-irradiation of levonorgestrel (1) in the crystalline state under a nitrogen atmosphere yielded its dimer, [17 alpha[1R-(1 alpha,2 beta,4a beta,4b alpha,10a alpha)]]-13-ethyl-17- [4- (2-ethyl-1,2,3,4a,4b,5,6,7,9,10,10a-dodecahydro-7-oxo-1-phenant renyl)-1- methylen-2-oxo-butoxy]-18,19-dinorpregna-4-en-20-in-3-one(3) , as the principal photoproduct. It was characterized from its spectral and analytical data. The single crystal X-ray crystallographic data of 1 indicated the possibility of its photochemical dimerisation.
authors: Institut für Pharmazeutische Chemie der Westfälischen Wilhelms-Universität, Münster, Germany.
authors: J
authors: J
authors: Reisch
authors: J
authors: J
authors: Zappel
authors: A R
authors: AR
authors: Rao
authors: G
authors: G
authors: Henkel
mesh_terms: D018360:Crystallography, X-Ray; D016912:Levonorgestrel / Q000737:chemistry* / Q000528:radiation effects; D014466:Ultraviolet Rays
chemical_list: D016912:Levonorgestrel