title: Association of Chlamydia trachomatis immunoglobulin gamma titers with dystrophic peritoneal calcification, psammoma bodies, adhesions, and hydrosalpinges.
abstract: OBJECTIVE
  To correlate Chlamydia trachomatis immunoglobulin gamma (IgG) titers with psammoma bodies, dystrophic peritoneal calcification, degree of calcification, adhesions, and hydrosalpinges.
  
  
  METHODS
  This is a prospective single-blinded histologic analysis of tissue and retrospective analysis of historical laboratory and clinical variables.
  
  
  METHODS
  Tertiary hospital and private practice patient charts.
  
  
  METHODS
  Sixty consecutive patients with C. trachomatis IgG titers reported on the coding sheets of a previous study for endometriosis.
  
  
  METHODS
  The histologic slides were reviewed in a blinded fashion for calcification. Previously used data sheets were reviewed for C. trachomatis IgG titers. Historical data, adhesion scores, hystrosalpingogram findings, and laparoscopic findings were obtained from charts.
  
  
  RESULTS
  Dystrophic calcification, psammoma bodies, moderate-to-severe dystrophic calcification and hydrosalpinges were associated with positive C. trachomatis IgG titers.
  
  
  CONCLUSIONS
  This study suggests relationship of C. trachomatis with dystrophic calcification, psammoma bodies, adhesions, and hydrosalpinges. This relationship suggests that C. trachomatis IgG titers can be used as a marker to help determine those infertility patients who might best benefit from hysterosalpingogram or laparoscopy and in clinical studies of endometriosis, infertility, pain, or ovarian cancer. However, there is no current data to suggest a need for therapy on the basis of a positive C. trachomatis IgG titer or of dystrophic peritoneal calcification.
authors: Baptist Memorial Hospital, University of Tennessee, Memphis.
authors: D C
authors: DC
authors: Martin
authors: V K
authors: VK
authors: Khare
authors: B E
authors: BE
authors: Miller
mesh_terms: D001826:Body Fluids / Q000378:metabolism; D002114:Calcinosis / Q000276:immunology* / Q000473:pathology; D002692:Chlamydia trachomatis / Q000276:immunology*; D005184:Fallopian Tube Diseases / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D010532:Peritoneal Diseases / Q000276:immunology* / Q000473:pathology; D011446:Prospective Studies; D000267:Tissue Adhesions / Q000276:immunology / Q000473:pathology
chemical_list: D007074:Immunoglobulin G