[Gentamycin resistant Enterobacteriaceae at a neonatal care unit].
A case of septicaemia in a seven-day-old infant with a gentamicin-resistant strain of Enterobacter cloacae prompted an epidemiological survey in a neonatal unit. Another 18 patients harboured gentamicin-resistant Enterobacteriaceae without symptoms. Control of the outbreak was achieved by cohort nursing, strict hygiene and reduction of aminoglycoside consumption by 50%. Efficiency of the measures was monitored by weekly faecal samples from all patients. All strains produced the aminoglycoside modifying enzyme AAC(3)II. The resistance was plasmid-mediated.
Balslev
T
T
Aalborg Sygehus, paediatrisk afdeling, Statens Seruminstitut, København.
Kristensen
B
B
Ebbesen
F
F
Schumacher
H
H
Korsager
B
B
D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology*; D005839:Gentamicins / Q000276:immunology* / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D015995:Prevalence
D005839:Gentamicins
Gentamycinresistente enterobakterier på en neonatalafdeling.