New discriminative chromosomal marker in adipose tissue tumors. The chromosome 8q11-q13 region in lipoblastoma.
Specific chromosome abnormalities characterize benign and malignant adipose tissue tumors and are of great diagnostic and clinical importance. Lipoblastoma is a rare benign adipose tumor that mimics myxoid liposarcoma histologically. Although only a few lipoblastomas have been investigated cytogenetically, it is increasingly clear that these adipose tissue tumor generally show rearrangements of 8q11-q13 region but lack the t(12;16) that allows these tumors to be distinguished from myxoid liposarcomas.
Dal Cin
P
P
Center for Human Genetics, University of Leuven, Belgium.
Sciot
R
R
De Wever
I
I
Van Damme
B
B
Van den Berghe
H
H
D002898:Chromosomes, Human, Pair 8; D005819:Genetic Markers; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008067:Lipoma / Q000235:genetics*; D008297:Male; D012983:Soft Tissue Neoplasms / Q000235:genetics*
D005819:Genetic Markers