title: IgA nephropathy associated with portal hypertension in liver cirrhosis due to non-alcoholic and non-A, non-B, non-C hepatitis.
abstract: A 69-year-old female was admitted to our hospital because of leg edema, proteinuria (2.1 g/day), and gross hematuria. She had non-alcoholic liver cirrhosis of unknown etiology. Esophageal varices also were found. Examination of the renal biopsy specimen revealed mesangial proliferative glomerulonephritis with IgA deposits. Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion. This case suggests that portal hypertension is involved in the pathogenesis of IgA nephropathy in liver cirrhosis.
authors: Department of Internal Medicine, Kasumigaura National Hospital, Tsuchiura.
authors: M
authors: M
authors: Nakamura
authors: A
authors: A
authors: Ohishi
authors: R
authors: R
authors: Watanabe
authors: K
authors: K
authors: Kaneko
authors: N
authors: N
authors: Aosaki
authors: T
authors: T
authors: Iigaya
authors: T
authors: T
authors: Monma
authors: H
authors: H
authors: Sugiura
authors: Y
authors: Y
authors: Miyoshi
authors: K
authors: K
authors: Hamaguchi
mesh_terms: D000368:Aged; D005260:Female; D005922:Glomerulonephritis, IGA / Q000209:etiology* / Q000473:pathology; D006505:Hepatitis / Q000150:complications* / Q000473:pathology; D006801:Humans; D006975:Hypertension, Portal / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D007678:Kidney Glomerulus / Q000648:ultrastructure; D008103:Liver Cirrhosis / Q000209:etiology* / Q000473:pathology; D008854:Microscopy, Electron; D011433:Propranolol / Q000627:therapeutic use
chemical_list: D011433:Propranolol