Nuclear bodies associated with core particles of hepatitis B virus in a healthy carrier.
An unusual association of nuclear bodies (NB) with core particles of hepatitis B virus (HBV) is described in a healthy carrier who histologically showed ground glass hepatocytes with occasional sanded-nuclei. Ultrastructurally, many hepatocytes had typical features of HBV infection. Unexpectedly, a few cells contained previously undescribed complexes of NB studded with a number of HBV core particles. The ultrastructural characteristics of these complexes and their possible relation to HBV morphogenesis are briefly discussed.
Makarova
N
N
Latvian Medical Academy, Riga.
Pasquinelli
G
G
Martinelli
G N
GN
D002353:Carrier State / Q000821:virology*; D002467:Cell Nucleus / Q000821:virology*; D006509:Hepatitis B / Q000473:pathology / Q000821:virology*; D006515:Hepatitis B virus / Q000648:ultrastructure*; D006801:Humans; D008099:Liver / Q000473:pathology / Q000648:ultrastructure*; D008854:Microscopy, Electron