Styrene-7,8-oxide in blood of workers exposed to styrene.
A field study was carried out on 13 workers exposed to styrene vapors at time-weighted average concentrations between 10 and 73 ppm. The reactive intermediate styrene-7,8-oxide was determined in blood samples using a direct gas chromatographic method. Styrene-7,8-oxide concentrations were in the range between 0.9 and 4.1 micrograms/l blood. Linear correlations were found between styrene-7,8-oxide in blood and styrene in ambient air and blood. For an exposure concentration of 20 ppm styrene (German MAK value) a steady-state level of about 1 microgram styrene-7,8-oxide/l blood was calculated.
Korn
M
M
Institut für Arbeits- und Sozialmedizin, Tübingen, Germany.
Gfrörer
W
W
Filser
J G
JG
Kessler
W
W
D000328:Adult; D002849:Chromatography, Gas; D004852:Epoxy Compounds / Q000097:blood*; D005858:Germany; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D020058:Styrene; D013343:Styrenes / Q000009:adverse effects / Q000097:blood / Q000493:pharmacokinetics*
D004852:Epoxy Compounds; D013343:Styrenes; D020058:Styrene; C013690:styrene oxide