[Contribution of myocardial biopsy and immunohistochemistry to the prognostic evaluation of cardiac amyloidosis].
The authors report four cases of cardiac amyloidosis, the diagnosis of which was confirmed by endomyocardial biopsy. They underline the value of immuno-histological studies with labelling of the biopsy fragments with anti-transthyretin and anti-light chain immunoglobulin antibodies. This approach provides a more precise typing of amyloidosis and a more accurate evaluation of the prognosis.
Van de Walle
J P
JP
Service de pathologie cardiovasculaire, Marseille Armées.
Fourcade
L
L
Panagides
D
D
Harle
J R
JR
Pellissier
J F
JF
Touze
J E
JE
Bory
M
M
D000328:Adult; D000368:Aged; D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis; D001706:Biopsy; D009202:Cardiomyopathies / Q000175:diagnosis / Q000209:etiology*; D004699:Endocardium / Q000473:pathology; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D011228:Prealbumin / Q000276:immunology; D011379:Prognosis
D000682:Amyloid; D011228:Prealbumin
Apport de la biopsie myocardique et de l'étude immunohistochimique à l'évaluation pronostique des amyloses cardiaques.