title: Immunohistochemical staining for thyroglobulin in poorly differentiated carcinoma of the thyroid.
abstract: Paraffin sections of 14 specimens of poorly differentiated tumours of the thyroid were stained for thyroglobulin using polyclonal antibodies and a streptavidin-biotin peroxidase staining system. The better differentiated areas showed positive staining, while the poorly differentiated areas gave weakly positive or negative staining. Thyroglobulin staining is useful in attributing a thyroid epithelial cell origin to a tumour, but negative staining does not exclude this.
authors: Department of Pathology, Faculty of Medicine, University of Peradeniya, Sri Lanka.
authors: N
authors: N
authors: Ratnatnga
authors: S
authors: S
authors: Ramadasa
mesh_terms: D002277:Carcinoma / Q000737:chemistry* / Q000145:classification; D006801:Humans; D007124:Immunoenzyme Techniques; D013954:Thyroglobulin / Q000032:analysis*; D013964:Thyroid Neoplasms / Q000737:chemistry* / Q000145:classification
chemical_list: D013954:Thyroglobulin