The minor groove covalent reactive drugs anthramycin and (+)-CC-1065 and their interstrand cross-linking derivatives.
Hurley
L H
LH
College of Pharmacy, Drug Dynamics Institute, University of Texas at Austin.
D000876:Anthramycin / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D001483:Base Sequence; D001569:Benzodiazepines / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D003432:Cross-Linking Reagents / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D004247:DNA / Q000187:drug effects* / Q000378:metabolism*; D018736:DNA Adducts / Q000096:biosynthesis; D000080890:Duocarmycins; D006801:Humans; D007211:Indoles / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D007933:Leucomycins / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation
D000903:Antibiotics, Antineoplastic; D003432:Cross-Linking Reagents; D018736:DNA Adducts; D000080890:Duocarmycins; D007211:Indoles; D007933:Leucomycins; D000876:Anthramycin; D001569:Benzodiazepines; C018782:CC 1065; D004247:DNA