Mechanisms of hemostasis and arterial thrombosis.
The term hemostasis refers to the critical physiologic response to arterial injury that serves to limit hemorrhage. Thrombosis, a pathologic process, results when the coagulation system is excessively activated in the absence of bleeding. The mechanisms that regulate these processes, as well as the mode of action of pharmacologic agents that attenuate thrombosis, are discussed.
Fiore
L D
LD
Boston University School of Medicine, Massachusetts.
Deykin
D
D
D000789:Angina, Unstable / Q000097:blood / Q000209:etiology; D001779:Blood Coagulation Factors; D005342:Fibrinolysis; D005343:Fibrinolytic Agents; D006487:Hemostasis; D006801:Humans; D009203:Myocardial Infarction / Q000097:blood / Q000209:etiology; D015539:Platelet Activation; D013927:Thrombosis / Q000097:blood
D001779:Blood Coagulation Factors; D005343:Fibrinolytic Agents