Neurotransmitter transporters: three important gene families for neuronal function.
Three distinct gene families encode transporter proteins that aid in temporal and spatial buffering of neurotransmitter and neurotransmitter metabolite concentrations and allow neurons to cycle and recycle transmitter molecules. Analyses of these gene families and their products are likely to enhance understanding of the molecular neurobiology of neuronal function and may elucidate contributors to the genetic etiologies of neurological and psychiatric disease.
Uhl
G R
GR
Molecular Neurobiology Branch, NIDA, Baltimore, MD 21224.
Johnson
P S
PS
D000595:Amino Acid Sequence; D027322:Amino Acid Transport System X-AG; D000818:Animals; D001692:Biological Transport; D002352:Carrier Proteins / Q000096:biosynthesis* / Q000737:chemistry / Q000235:genetics*; D002712:Chlorides / Q000378:metabolism; D006023:Glycoproteins / Q000096:biosynthesis* / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D009474:Neurons / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000378:metabolism*; D017433:Protein Structure, Secondary; D012964:Sodium / Q000378:metabolism
D027322:Amino Acid Transport System X-AG; D002352:Carrier Proteins; D002712:Chlorides; D006023:Glycoproteins; D018377:Neurotransmitter Agents; D012964:Sodium