Sodium/calcium exchanger in olfactory receptor neurones of Xenopus laevis.
Ca2+ ions enter neurones through various types of calcium and cation channels. The mechanisms by which Ca2+ ions are spatially buffered and expelled from neurones have been studied considerable less. Using calcium imaging in conjunction with the patch clamp technique, we investigated the Na/Ca exchanger in olfactory neurones and found evidence for its localization on the dendrite. It is suggested that this tends to decouple increases in [Ca2+]i occurring in the transduction compartments of the cell from processes in the soma.
Jung
A
A
Physiologisches Institut, Universität Göttingen, Germany.
Lischka
F W
FW
Engel
J
J
Schild
D
D
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D002794:Choline / Q000494:pharmacology; D008856:Microscopy, Fluorescence; D009475:Neurons, Afferent / Q000187:drug effects / Q000378:metabolism*; D009831:Olfactory Mucosa / Q000166:cytology; D018408:Patch-Clamp Techniques; D010786:Photoreceptor Cells / Q000502:physiology; D018035:Receptors, Odorant / Q000187:drug effects / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*; D019831:Sodium-Calcium Exchanger; D014982:Xenopus laevis
D002352:Carrier Proteins; D018035:Receptors, Odorant; D019831:Sodium-Calcium Exchanger; D012964:Sodium; D002794:Choline; D002118:Calcium