Reproducibility of the electric response components in clinical electrocochleography.
The reproducibility of transtympanic electrocochleographic components was investigated in normal-hearing subjects and in patients with Menière's disease. The electric responses to short clicks and long tone bursts were studied using repeated stimuli within the same test (intratest), and after replacement of all electrodes (intertest). The parameters of the response to clicks, such as the SP/AP (summating potential/action potential) ratio and the width of the complex as well as the amplitudes of the response to clicks presented at fast repetition rate, were analyzed. Absolute amplitudes of the SP were measured using long tone bursts of 4, 2 and 1 kHz. It was found that the intratest reproducibility of the responses was good for all the parameters. The intertest responses showed a larger variability, particularly when long bursts were used. Parameters obtained from hydroptic ears, which could be considered mainly representative for the SP, showed the largest variability of the responses. The effect of replacement of the electrodes amounted to less than 35% of the total intertest variability which would indicate that replacement of the electrodes did not significantly influence the recordings obtained at different measurement occasions in the same patient. The upper normal limit value indicating changes which could be contributed to biological fluctuations and the method of measurements were calculated for each response parameter. Changes exceeding these values could thus be attributed to a real change in the electric cochlear potentials, at the 95% confidence level.
Densert
B
B
Department of Otolaryngology, University of Lund, Sweden.
Arlinger
S
S
Sass
K
K
Hergils
L
L
D000158:Acoustic Impedance Tests; D001300:Audiometry, Evoked Response; D003051:Cochlea / Q000503:physiopathology*; D007758:Ear, Inner / Q000503:physiopathology*; D006309:Hearing / Q000502:physiology*; D006801:Humans; D008575:Meniere Disease / Q000175:diagnosis* / Q000503:physiopathology*; D015203:Reproducibility of Results