[Somatostatin receptor scintigraphy in preoperative diagnosis of the site of endocrine gastrointestinal tumors].
To determine the value of somatostatin-receptor scintigraphy in the localization of various endocrine gastrointestinal tumors, we compared the results obtained with this new technique with the results obtained with computed tomography and sonography. We could not find an overall advantage of somatostatin-receptor scintigraphy as compared to computed tomography or sonography in the localization of intestinal carcinoids (n = 13), gastrinomas (n = 12), functionally non-active endocrine pancreatic tumors (n = 8) and various other endocrine pancreatic tumors (n = 4). In 2 patients with endocrine pancreatic tumors however, the tumors were localized preoperatively only by somatostatin-receptor scintigraphy. Somatostatin-receptor scintigraphy may occasionally be helpful in the localization of gastrointestinal endocrine tumors if these tumors are not localized by conventional imaging studies. Somatostatin-receptor scintigraphy does not solve the problem to localize small endocrine tumors.
Weinel
R J
RJ
Klinik für Allgemeinchirurgie, Philipps-Universität Marburg.
Kisker
O
O
Joseph
K
K
Welcke
U
U
Zaraca
F
F
Rothmund
M
M
D014408:Biomarkers, Tumor / Q000032:analysis*; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D015408:Gastrinoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D005770:Gastrointestinal Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007205:Indium Radioisotopes; D007340:Insulinoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D018761:Multiple Endocrine Neoplasia Type 1 / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D015282:Octreotide / Q000031:analogs & derivatives / Q000627:therapeutic use; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery; D009384:Paraneoplastic Endocrine Syndromes / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery; D004369:Pentetic Acid / Q000031:analogs & derivatives; D017481:Receptors, Somatostatin / Q000032:analysis*; D015899:Tomography, Emission-Computed, Single-Photon; D015043:Zollinger-Ellison Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery
D014408:Biomarkers, Tumor; D007205:Indium Radioisotopes; D017481:Receptors, Somatostatin; C071632:SDZ 215-811; D004369:Pentetic Acid; D015282:Octreotide
Die Somatostatinreceptor-Szintigraphie in der präoperativen Lokalisationsdiagnostik endokriner gastrointestinaler Tumoren.