title: [Therapy and follow-up of superficial bladder cancer in in patients less than 30 years of age].
abstract: Transitional cell carcinoma of the bladder is relatively uncommon in patients under 30 years old. We treated 11 patients with superficial bladder carcinoma under 30 years of age. In 10 cases gross haematuria was the most common presenting symptom. The pathological reports of the patients revealed grade I, stage Ta transitional cell carcinoma in seven patients, grade I, stage T1 tumour in two patients and bladder myoma and inverted papilloma in two patients each. Four of nine patients with superficial bladder carcinoma stayed free of disease for 1-10 years after initial transurethral resection (TUR). Four patients suffered multiple tumour recurrences 1-4 months after initial TUR, with progressive disease in three cases. One patient was lost to follow-up after primary operation. In the two patients with benign bladder tumours, no recurrences were observed within 12 and 48 months. Owing to the high rates of recurrence (44%) and tumour progression (33%) all patients under 30 years of age should be treated as aggressively as necessary on the basis of the grade and stage of the tumour, in the same way older patients.
authors: Abteilung Urologie, Universität Mainz.
authors: K
authors: K
authors: Erpenbach
authors: S
authors: S
authors: Roth
authors: P
authors: P
authors: Rathert
mesh_terms: D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D003952:Diagnostic Imaging; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008889:Military Personnel; D009214:Myoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D018308:Papilloma, Inverted / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
vernacular_title: Therapie und Verlauf des oberflächlichen Harnblasenkarzinoms bei Patienten unter 30 Jahren.