title: Differences in serum interleukin-6 (IL-6) between healthy dextral and non-dextral subjects.
abstract: Serum interleukin-6 (IL-6) was measured in picograms/ml pg/ml using an immunoassay (ELISA) in healthy individuals (n = 148), of whom 128 were classified as dextral and 20 as non-dextral, as per a laterality questionnaire. Only 3 (15%) non-dextral individuals had serum IL-6 levels above the lower limit of the assay sensitivity as compared to 59 (46%) of dextral individuals (P < 0.013). There were no significant correlations between previously determined mitogen stimulated interleukin-2 production and autoantibodies in a subset of the same individuals. While this data does not provide casual information, it adds to the evidence of the asymmetric regulation of immune functions by the cerebral hemispheres.
authors: Department of Psychiatry (Immunopsychiatry Program), Western Psychiatric Institute and Clinic, Pittsburg, PA 15213-2593.
authors: K N
authors: KN
authors: Chengappa
authors: R
authors: R
authors: Ganguli
authors: Z W
authors: ZW
authors: Yang
authors: G
authors: G
authors: Schurin
authors: J S
authors: JS
authors: Brar
authors: J A
authors: JA
authors: Rosenbleet
authors: B S
authors: BS
authors: Rabin
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D007839:Functional Laterality; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D012016:Reference Values; D011795:Surveys and Questionnaires
chemical_list: D001323:Autoantibodies; D015850:Interleukin-6