[BCG-vaccination in neonates as a cause of osteomyelitis--an argument against BCG-vaccination?].
BCG-osteomyelitis is a rare complication of BCG-vaccination. By means of a case report clinical and immunological findings are discussed. Contrary to the undramatic clinical symptoms the x-ray showed pronounced osteolytic lesions in the sternum. The bacteriological examination demonstrated mycobacteria of BCG-type. Immunological investigations presented normal humoral and cellular immunity. The therapy (curettage, antituberculous drugs) was effective. In spite of this complication the BCG-vaccination is furthermore recommended.
Walter
S
S
Kinderklinik, Universität Leipzig.
Handrick
W
W
Tischer
W
W
Hörmann
D
D
Borte
M
M
D001500:BCG Vaccine / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008297:Male; D010014:Osteolysis; D010019:Osteomyelitis / Q000209:etiology* / Q000473:pathology; D013249:Sternum / Q000473:pathology
D001500:BCG Vaccine
BCG-Impfung im Neugeborenenalter als Ursache einer Osteomyelitis--ein Argument gegen die BCG-Impfung?