title: A fatality due to flurazepam.
abstract: A fatality attributed to suicidal ingestion of up to 2.2 grams of flurazepam is described. The deceased was a 52-year old female with a history of depression and suicidal attempts. No significant pathology was found at autopsy. Full toxicological analyses detected only flurazepam and metabolites in her tissues. The concentrations of flurazepam in femoral blood, liver, bile, vitreous humor and urine were 5.5 mg/L, 130 mg/kg, 33 mg/L, 1.3 mg/L and 3.3 mg/L, respectively. Analysis of gastric contents showed 600 mg of flurazepam. Desalkylflurazepam was also detected in blood, liver, bile and vitreous, but at much lower concentrations than the parent compound.
authors: Victorian Institute of Forensic Pathology, Monash University, South Melbourne, Australia.
authors: I M
authors: IM
authors: McIntyre
authors: M L
authors: ML
authors: Syrjanen
authors: K L
authors: KL
authors: Lawrence
authors: C A
authors: CA
authors: Dow
authors: O H
authors: OH
authors: Drummer
mesh_terms: D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D017248:Enzyme Multiplied Immunoassay Technique; D005260:Female; D005479:Flurazepam / Q000032:analysis / Q000506:poisoning*; D006801:Humans; D008875:Middle Aged; D013405:Suicide
chemical_list: D005479:Flurazepam