Coat protein-mediated resistance in transgenic plants.
This review describes the proposed mechanism(s) of classical virus cross-protection in plants, followed by those suggested for coat protein-mediated resistance (CP-mediated resistance). Although both have common features, cross-protection is thought to be a complex response caused by the replication and expression of the entire viral genome, whereas the resistance conferred by the expression of a virus coat protein gene is more limited. The term genetically engineered cross-protection is frequently used because in many cases the phenotype of resistance mimics that of cross-protection. However, CP-mediated resistance, although a narrow term, more accurately describes the resistance that results from the expression of a virus CP gene in transgenic plants.
Hackland
A F
AF
Department of Microbiology, University of Cape Town, Rondebosch, South Africa.
Rybicki
E P
EP
Thomson
J A
JA
D002213:Capsid / Q000096:biosynthesis* / Q000235:genetics; D015870:Gene Expression; D005818:Genetic Engineering / Q000379:methods; D007113:Immunity, Innate; D010935:Plant Diseases / Q000235:genetics; D010942:Plant Viruses / Q000235:genetics*; D030821:Plants, Genetically Modified / Q000502:physiology*