title: Field study for reduction of spread of Aujeszky's disease virus in finishing pigs with different vaccination regimes.
abstract: In a comparative field trial in feeder-finishing pigs on 8 farms with a history of Aujeszky's disease (AD) the incidence and spread of Aujeszky's disease virus (ADV) and serological effects of vaccination were investigated. Nobi-Porvac Aujeszky live (strain Begonia) was used either dissolved in the aqueous adjuvant Diluvac Forte (DF) or in Unisorve (watery solvent) to vaccinate whole feeder-finishing units one or two times. Incidence of ADV measured by gI ELISA within infected finishing units was significantly reduced by the use of the adjuvant solvent DF. Furthermore the use of the adjuvant DF improved the efficiency of the vaccination as was shown by significantly higher virus-neutralising (VN) titres at slaughter time. The number of samples without detectable VN antibodies at the end of the finishing period was significantly lower in the finishing units vaccinated once with DF. The latter effect, though not statistically significant, was also seen after double vaccination in combination with the adjuvant. The investigation of VN antibody titres at the moment of the first vaccination (around 10 weeks of age) suggests that on problem farms the spread of infection can start earlier than that time.
authors: Intervet International B.V., Boxmeer, The Netherlands.
authors: P
authors: P
authors: Broers
authors: N
authors: N
authors: Visser
authors: W
authors: W
authors: Egger
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D011558:Herpesvirus 1, Suid / Q000276:immunology*; D015994:Incidence; D008297:Male; D011557:Pseudorabies / Q000517:prevention & control* / Q000635:transmission; D022421:Pseudorabies Vaccines; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control* / Q000635:transmission; D014611:Vaccination / Q000379:methods / Q000662:veterinary*; D014613:Vaccines, Attenuated; D014765:Viral Vaccines / Q000008:administration & dosage*
chemical_list: D000914:Antibodies, Viral; D022421:Pseudorabies Vaccines; D014613:Vaccines, Attenuated; D014765:Viral Vaccines