Segmental analysis of resting echocardiographic function and stress scintigraphic perfusion: implications for myocardial viability.
In 73 patients with coronary artery disease, we performed segmental analysis of resting two-dimensional echocardiography and stress thallium-201 single photon emission computed tomographic scintigraphy with 24-hour delayed imaging to test the hypotheses that (1) combined analysis of stress thallium-201 scintigraphy (with 24-hour redistribution) and echocardiography provides an evaluation of the viability of most myocardial segments; and (2) the severity of the scintigraphic perfusion abnormality in a given segment is equivalent to the severity of its echocardiographically determined functional impairment. Scintigraphy showed 14% of the 1168 segments analyzed to have fixed severe defects. Echocardiography showed 11% of the 1070 segments analyzed to be akinetic or dyskinetic. However, with combined analysis, only 62 (5%) segments showed no evidence of viability by either imaging technique. We conclude that in this group of patients, 95% of segments have evidence of viability by one of these two conventional imaging techniques.
Foster
E
E
Department of Medicine, Moffitt Hospital, University of California, San Francisco 94143-0214.
O'Kelly
B
B
LaPidus
A
A
Sandler
D
D
Tucker
K
K
Dae
M
M
Schiller
N B
NB
Botvinick
E H
EH
D000368:Aged; D006328:Cardiac Catheterization; D016009:Chi-Square Distribution; D003327:Coronary Disease / Q000000981:diagnostic imaging; D004452:Echocardiography / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D005080:Exercise Test / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012146:Rest; D012189:Retrospective Studies; D013794:Thallium Radioisotopes; D013997:Time Factors; D014022:Tissue Survival; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods / Q000706:statistics & numerical data
D013794:Thallium Radioisotopes