title: Action of testosterone on the anti-müllerian activity of the chick embryonic testis assayed in vivo by organotypic grafting.
abstract: The implantation of embryonic testis grafts into female chick embryos induces the regression of their müllerian ducts (MDs) in a certain number of cases. The treatment of either the grafts or the grafted females with testosterone propionate (TP) results in a significant increase in the number of MD regressions observed. Our data are interpretable in terms of a direct activation by TP of the anti-müllerian activity of the embryonic testis. We discuss a possible mechanism accounting for the synergistic action of testosterone and anti-müllerian hormone.
authors: Faculté de Médecine Paul Broca, Laboratoire d'Histo-Embryologie, Université Bordeaux II, Bordeaux, France.
authors: F
authors: F
authors: Ichas
authors: N
authors: N
authors: Faucounau
authors: R
authors: R
authors: Stoll
authors: R
authors: R
authors: Maraud
mesh_terms: D000818:Animals; D054304:Anti-Mullerian Hormone; D002642:Chick Embryo; D005260:Female; D006023:Glycoproteins; D006131:Growth Inhibitors / Q000032:analysis / Q000502:physiology*; D008297:Male; D009095:Mullerian Ducts / Q000737:chemistry / Q000187:drug effects* / Q000196:embryology; D013735:Testicular Hormones / Q000032:analysis / Q000502:physiology*; D013737:Testis / Q000196:embryology* / Q000637:transplantation; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D006023:Glycoproteins; D006131:Growth Inhibitors; D013735:Testicular Hormones; D013739:Testosterone; D054304:Anti-Mullerian Hormone