[IgD myeloma with skin tumor].
A 66-year-old man was treated for IgD (lambda) multiple myeloma with 2mg/day melphalan and 20mg/day prednisolone. Subsequently, he developed pneumonia for which he received antibiotics, an antifungal agent and granulocyte colony-stimulating factor (G-CSF) twice. Myeloma cells appeared in the peripheral blood 10 days after the second G-CSF course. In addition, skin tumors developed on his extremities and chest 14 days after the second use of G-CSF. The skin tumors consisted of immunohistochemically IgD (lambda)-positive myeloma cells. The skin tumors may have been formed from the bone marrow by metastasis, a very rare occurrence in multiple myeloma. Before the development of the tumors we administered G-CSF, which may also have been related to the formation of the skin tumors.
Kawakami
K
K
Department of Hematology, Showa University School of Medicine.
Ishiyama
T
T
Onizuka
T
T
Hino
K
K
Tomoyasu
S
S
Tsuruoka
N
N
D000368:Aged; D006801:Humans; D007072:Immunoglobulin D / Q000378:metabolism*; D008297:Male; D009101:Multiple Myeloma / Q000276:immunology / Q000473:pathology*; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*
D007072:Immunoglobulin D