Molecular cloning and sequencing of a human cDNA encoding ornithine decarboxylase antizyme.
We report the cloning of a cDNA encoding the human homolog of ornithine decarboxylase antizyme from a human gingival fibroblast cDNA library. The human antizyme is 84% identical to the rat sequence and shows almost no homology to the E. coli antizyme. Northern analysis studies show that this gene is expressed in both human gingival and synovial fibroblasts.
Tewari
D S
DS
Department of Biochemistry/Molecular Biology, Philadelphia College of Osteopathic Medicine, PA 19131.
Qian
Y
Y
Thornton
R D
RD
Pieringer
J
J
Taub
R
R
Mochan
E
E
Tewari
M
M
D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000737:chemistry*; D005881:Gingiva / Q000201:enzymology; D006801:Humans; D008969:Molecular Sequence Data; D065108:Ornithine Decarboxylase Inhibitors; D011506:Proteins / Q000235:genetics*; D013583:Synovial Membrane / Q000201:enzymology
D018076:DNA, Complementary; D065108:Ornithine Decarboxylase Inhibitors; D011506:Proteins; C031017:ornithine decarboxylase antizyme