[Serological markers for hepatitis A, B and C in Madagascar. First investigation in a rural area].
The first serological survey of hepatitis A, B and C virus infection was carried out in Madagascar during 1993 in two rural villages (653 sera) of the middle-west. This study shows a high frequency of positivity of hepatitis A virus markers (94.9%). Hepatitis A is acquired in early childhood. The data show the high frequency of positivity of hepatitis B (HBV) markers: in the two villages 72.5% and 89.8% have one marker, and seroprevalence of HBs antigene is 18.9% and 30.5%. Hepatitis B also is acquired in early childhood. The data show that not only hepatitis A and B but also hepatitis C is highly prevalent (2.2% and 5.8%). There was an increase in HCV antibody prevalence with age.
Morvan
J M
JM
Institut Pasteur de Madagascar, Tananarive.
Boisier
P
P
Andrianimanana
D
D
Razainirina
J
J
Rakoto-Andrianarivelo
M
M
Roux
J F
JF
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006506:Hepatitis A / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006509:Hepatitis B / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006513:Hepatitis B e Antigens / Q000032:analysis; D006526:Hepatitis C / Q000276:immunology*; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007223:Infant; D008270:Madagascar; D008297:Male; D012424:Rural Population
D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens
Les marqueurs sérologiques des hépatites A, B et C à Madagascar. Première enquête en zone rurale.