Dietary zinc-methionine enhances mononuclear-phagocytic function in young turkeys. Zinc-methionine, immunity, and Salmonella.
The ability of dietary zinc-methionine (Zn-Met) to enhance mononuclear-phagocytic function against Salmonella arizona and enteritidis was investigated in young turkeys. Feed/gain and body wt gain at 21 d of age were not affected by Zn-Met. The addition of 30 or 45 ppm Zn from Zn-Met to a Zn adequate diet significantly increased cutaneous basophil hypersensitivity to phytohemagglutinin-P. The clearance of intravenously administered S. enteritidis from blood was not affected by 30 ppm of supplemental Zn from Zn-Met. However, 30 ppm Zn from Zn-Met increased the reduction of intravenously administered S. arizona from spleen. Percentages of myeloid and mononuclear-phagocytic cells before and after S. enteritidis infection were not affected by supplemental Zn-Met. Turkeys supplemented with Zn-Met showed enhanced in vitro phagocytosis of S. enteritidis by Sephadex-elicited abdominal exudate cells. The phagocytosis of S. arizona was unaffected by Zn-Met.
Kidd
M T
MT
Department of Poultry Science, North Carolina State University, Raleigh 27695-7608.
Qureshi
M A
MA
Ferket
P R
PR
Thomas
L N
LN
D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001491:Basophils / Q000166:cytology / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002448:Cell Adhesion / Q000187:drug effects; D015169:Colony Count, Microbial; D007428:Intradermal Tests / Q000662:veterinary; D007963:Leukocytes, Mononuclear / Q000187:drug effects*; D008099:Liver / Q000378:metabolism; D008264:Macrophages / Q000187:drug effects; D008297:Male; D008715:Methionine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D010586:Phagocytes / Q000187:drug effects*; D010835:Phytohemagglutinins / Q000378:metabolism / Q000494:pharmacology; D011201:Poultry Diseases / Q000097:blood / Q000188:drug therapy / Q000276:immunology; D011897:Random Allocation; D012475:Salmonella / Q000187:drug effects / Q000276:immunology; D012481:Salmonella Infections, Animal / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D012477:Salmonella enteritidis / Q000187:drug effects / Q000276:immunology; D012867:Skin / Q000166:cytology / Q000187:drug effects; D013154:Spleen / Q000276:immunology / Q000382:microbiology; D014422:Turkeys; D015032:Zinc / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use
D009942:Organometallic Compounds; D010835:Phytohemagglutinins; C028784:phytohemagglutinin-P; C074508:zinc methionine; D008715:Methionine; D000469:Alkaline Phosphatase; D015032:Zinc