[Tumor markers in the follow-up of colorectal cancers].
The aim of this work was to review the usefulness of tumour markers in the follow-up of colo-rectal cancers after operation. The carcinoembryonic antigen (CAE) is the most sensitive marker for early detection of relapse. It can be combined with CA 19-9 assay, increasing the sensitivity and specificity of the tests. These assays are useful because one half of the relapsing tumours can be resected leading to a survival rate of 40%. CAE and CA 19-9 must be assayed within 2 months to 2 years after surgery to be effective screening tests. Presently, the widespread use of labelled monoclonal antibodies can, in certain tests, localize recurrent tumours before a second look operations.
Richelme
H
H
Service de Chirurgie abdominale et thoracique, Nice.
Chazal
M
M
Namer
M
M
Benchimol
D
D
D000911:Antibodies, Monoclonal / Q000276:immunology; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000276:immunology*; D006801:Humans; D011877:Radionuclide Imaging; D013997:Time Factors
D000911:Antibodies, Monoclonal; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen
Les marqueurs tumoraux dans le suivi des cancers colo-rectaux.