title: [Comparative evaluation of fibrogenesis and toxicity of asbestos-containing heat-proof materials].
abstract: The article deals with the results of studies analyzing the fibrogenic activity and toxicity of asbestos-containing heat insulators exemplified by asbestos board, vulcanite and asbestos vermiculite. Physical and chemical parameters of the studied dust are presented. All studied dust types have the distinct fibrogenic activity, the highest one was seen in asbestos board. The studied dust types could be classified according to the acute toxicity: asbestos board (DL50-3.2 +/- 0.09 g/kg), chrysotile asbestos (DL50-2.0 +/- 0.08 g/kg), vulcanite (DL50-1.9 +/- 0.08 g/kg) and asbestos vermiculite (DL50-0.7 +/- 0.04 g/kg). The article touches upon the probable acting mechanism of acute toxicity of asbestos and asbestos-containing dust.
authors: S V
authors: SV
authors: Kashanskiĭ
authors: F M
authors: FM
authors: Kogan
authors: L G
authors: LG
authors: Malysheva
authors: V A
authors: VA
authors: Zykova
mesh_terms: D000818:Animals; D001194:Asbestos / Q000737:chemistry / Q000633:toxicity*; D001195:Asbestosis / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D004391:Dust / Q000009:adverse effects*; D005260:Female; D006358:Hot Temperature; D051381:Rats; D013997:Time Factors
chemical_list: D004391:Dust; D001194:Asbestos
vernacular_title: Sravnitelńaia otsenka fibrogennosti i tiksichnosti asbestsoderzhashchikh teploizoliatsionnykh materialov.