Direct immunofluorescence vs. culture for detecting HSV in oral ulcers: a comparison.
Diagnostic tests may be necessary to determine the cause of oral ulcers. Direct immunofluorescence staining of oral smears supplies results much more quickly than viral culture, the "gold standard" for diagnosing HSV lesions. This study compares the sensitivity and specificity of direct immunofluorescence staining vs. viral culture and evaluates the usefulness of the two techniques for the general dental practitioner.
MacPhail
L A
LA
Department of Stomatology, School of Dentistry, University of California, San Francisco 94143.
Hilton
J F
JF
Heinic
G S
GS
Greenspan
D
D
D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal; D005455:Fluorescent Antibody Technique; D006679:HIV Seropositivity; D018259:Herpesvirus 1, Human / Q000302:isolation & purification*; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D013283:Stomatitis, Herpetic / Q000175:diagnosis*; D014456:Ulcer / Q000821:virology; D014776:Virus Cultivation
D000911:Antibodies, Monoclonal; D011933:Reagent Kits, Diagnostic