[Usefulness of 99mTc-PMT SPECT and 18F-FDG PET in diagnosing orbital metastasis of hepatocellular carcinoma].
We reported a case in which 99mTc-PMT scintigraphy was useful in diagnosing orbital metastasis of HCC. The case involved a 70 y.o. male, who had undergone nine transcatheter arterial embolizations over two years because of HCC and who had a past history of gastric cancer. The patient had complained of headache and visual disturbance for two months. Cranial CT and MRI studies showed a large homogeneous mass with remarkable bone destruction in the right lateral orbital wall. Because AFP was elevated, orbital metastasis of HCC was suspected, and 99mTc-PMT scanning was performed. On the planar and SPECT images, very high uptake was found in the right orbital tumor. The FDG-PET study showed remarkable hypermetabolism in the medial portion of tumor and follow-up MRI revealed that the tumor had expanded and invaded to the medial side of the orbit. 99mTc-PMT scanning was critical in diagnosing this case of orbital metastasis, and FDG-PET imaging was useful in determining the most active portion of the tumor.
Hosokawa
C
C
Department of Radiology, Osaka City University Medical School.
Kawabe
J
J
Okamura
T
T
Kamino
T
T
Ikeda
H
H
Ochi
H
H
Onoyama
Y
Y
D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000556:secondary*; D003847:Deoxyglucose / Q000031:analogs & derivatives*; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D015609:Organotechnetium Compounds; D011237:Predictive Value of Tests; D011730:Pyridoxal / Q000031:analogs & derivatives*; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon; D014364:Tryptophan / Q000031:analogs & derivatives*
D005462:Fluorine Radioisotopes; D015609:Organotechnetium Compounds; C038081:technetium Tc 99m pyridoxyl-5-methyltryptophan; D019788:Fluorodeoxyglucose F18; D011730:Pyridoxal; D014364:Tryptophan; D003847:Deoxyglucose