["Granulomatous slack skin"--cutaneous elastolytic lymphoma].
The term "granulomatous slack skin" (GSS) was introduced by Ackerman for a disease first described by Convit et al. in 1973. GSS represents a rare cutaneous lymphoma characterized by localized elastolytic lesions with a granulomatous infiltrate. We recently observed two male patients with the characteristic features of this disease. Both patients responded well to therapy with interferon-alpha 2b. In one patient clinical remission was stable under long-term treatment with clofazimine. We report on common features of these two patients and give a review of the cases published in the literature.
von den Driesch
P
P
Dermatologische Universitätsklinik, Erlangen.
Mielke
V
V
Simon
M
M
Staib
G
G
Tacke
J
J
Sterry
W
W
D001706:Biopsy; D002991:Clofazimine / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004535:Ehlers-Danlos Syndrome / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D004547:Elastic Tissue / Q000473:pathology; D005050:Etretinate / Q000627:therapeutic use; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D005050:Etretinate; D002991:Clofazimine
"Granulomatous slack skin"--kutanes elastolytisches Lymphom.