[Change in the composition of human skeletal muscles in amyotrophic lateral sclerosis].
Protein composition of human skeletal muscle impaired with lateral amyotropic sclerosis was studied by means of two-dimensional electrophoresis. Some protein fractions were altered. Characteristic property of all the preparations studied proved to be disappearance of three protein fractions of 35 kDa molecular mass and with pI 5.9, 6.0 and 6.1.
L I
LI
Kovalev
A I
AI
Khdaĭdatov
M A
MA
Galiuk
S S
SS
Shishkin
A S
AS
Niiazbekova
I N
IN
Gelashvili
I A
IA
Zavalishin
D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D005260:Female; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000378:metabolism*
Izuchenie belkovogo sostava skeletnoĭ myshtsy cheloveka pri bokovom amiotroficheskom skleroze.