[Changes in the immunobiochemical composition of the cerebrospinal fluid and the antitumor reactions of the local immune system in astrocytic brain tumors].
Pre- and postoperative immunochemical indices of cerebrospinal fluid (CSF) were investigated in 10 patients with fibrillary-protoplasmic astrocytoma and 10 patients with glioblastoma multiforme. Malignant neoplastic developments in the brain are associated with appearance of marked humoral reaction. Tumor-specific CSF changes observed comprise registration of ceruloplasmin immunomodulating proteins and alpha 2-macroglobulin. It is emphasized that biochemical antioxidant, antiprotease, energy-supplying systems are related directly to humoral immune reactions in the process of relevant postoperative rehabilitation.
Khil'ko
V A
VA
Khlunovskiĭ
A N
AN
Starchenko
A A
AA
Komarets
S A
SA
Lushnov
M S
MS
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D001254:Astrocytoma / Q000134:cerebrospinal fluid* / Q000276:immunology* / Q000601:surgery; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid* / Q000276:immunology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D015213:Neuroimmunomodulation; D010007:Osteochondritis / Q000134:cerebrospinal fluid / Q000276:immunology; D013166:Spondylitis / Q000134:cerebrospinal fluid / Q000276:immunology; D013997:Time Factors
Izmeneniia immunobiokhimicheskogo sostava tserebrospinal'noĭ zhidkosti i protivoopukholevye reaktsii mestnoĭ immunnoĭ sistemy pri opukholiakh golovnogo mozga astrotsitarnogo riada.