Efficacy of ceftriaxone versus cefazolin in the prophylactic management of extra-articular cortical violation of bone due to low-velocity gunshot wounds.
One hundred patients sustained gunshot wounds involving bone but not joint with a low-velocity bullet. Soft-tissue involvement was less than 1 cm at its greatest diameter. All patients were free from artery or nerve damage. No formal fixation of fracture was required. The results of the study suggest that patients need not be hospitalized longer than 2 days after an extra-articular, low-velocity gunshot wound that violates the cortex. In addition, through the use of long half-life antibiotics, such as ceftriaxone, the length of hospitalization may further be reduced to a day, while the potential for morbidity from infection is not increased.
Department of Orthopaedic Surgery, King/Drew Medical Center, Los Angeles, California.
K K
KK
Hansraj
L D
LD
Weaver
A O
AO
Todd
S M
SM
Taylor
M D
MD
Griffin
K M
KM
Dukhram
T P
TP
Judd
M S
MS
Hansraj
D000328:Adult; D000465:Algorithms; D001842:Bone and Bones / Q000293:injuries*; D002437:Cefazolin / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D003362:Cost-Benefit Analysis; D003365:Costs and Cost Analysis; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008297:Male; D011552:Pseudomonas Infections / Q000517:prevention & control*; D013997:Time Factors; D014946:Wound Infection / Q000517:prevention & control*; D014948:Wounds, Gunshot / Q000150:complications*
D002443:Ceftriaxone; D002437:Cefazolin