[Auto-analysis of corneal endothelium with photoelectrical scans and computer].
A quantitative analysis of corneal endothelial cells was made with photoelectrical scans and computer in 67 eyes. No difference was found as regards to the mean cell area and density between the endothelial analysis system and routine square counting. On the other hand, we analyzed corneal endothelial cells between 30 eyes wearing hard contact lens and 30 eyes of age- and sex-matched nonwearing control. The parameters, including cell density individual cell area, area, mean cell area, standard deviation, coefficient of variation of cell size (CV), maximum cell, minimum cell, the ratio of the maximum to minimum cell, and percentage of the hexagoal cells, were automatically displayed. The cell density and mean cell area also showed no significant difference (P > 0.05) between the wearers and nonwearing control, but the CV and the frequency of the hexagonal cells showed significant difference (P < 0.01). The ratio of maximum to minimum cell, the polymegethism and pleomorphism were obviously increased in the wearers. It is highly suggested that computer analysis system is of great value in evaluating corneal endothelial cells.
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China.
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Gong
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Shao
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Tao
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Wei
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Dai
D000293:Adolescent; D000328:Adult; D002452:Cell Count; D002648:Child; D003261:Contact Lenses; D004728:Endothelium, Corneal / Q000166:cytology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016555:Matched-Pair Analysis; D008875:Middle Aged