Deficient metanephric blastema--a cause of oligomeganephronia?
The histopathology and morphometric findings in two cases of oligomeganephronia occurring in a fetus and a preterm infant are reported. Metanephric blastema was decreased in the kidney from an 18-week fetus and was absent in the kidney from a liveborn preterm infant of 33 weeks gestation. These findings support the hypothesis that a primary deficiency of metanephric blastema may be a pathogenetic mechanism of oligomeganephronia.
Foster
S V
SV
Department of Pathology, Baylor College of Medicine, Houston, Texas.
Hawkins
E P
EP
D000015:Abnormalities, Multiple / Q000473:pathology; D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000473:pathology*; D008297:Male; D009399:Nephrons / Q000002:abnormalities* / Q000196:embryology*