Intrathecal morphine and clonidine in the management of spinal cord injury pain: a case report.
Neuropathic pain following spinal cord injury (SCI) can be difficult to manage using currently available pain management techniques. We describe a case of chronic pain following SCI which failed to respond to a variety of approaches including intrathecal administration of morphine. Use of clonidine in addition to the morphine resulted in a marked decrease in pain. The use of intrathecal clonidine with or without opioids may present an effective alternative in the management of intractable SCI pain and other forms of neuropathic pain.
Siddall
Philip J
PJ
Department of Anaesthesia and Pain Management, Royal North Shore Hospital, Sydney, NSW 2065 Australia Department of Acute Spinal Unit, Royal North Shore Hospital, Sydney, NSW 2065 Australia.
Gray
Megan
M
Rutkowski
Susan
S
Cousins
Michael J
MJ
D000328:Adult; D002908:Chronic Disease; D003000:Clonidine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D007260:Infusion Pumps; D007278:Injections, Spinal; D008297:Male; D009020:Morphine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D013119:Spinal Cord Injuries / Q000150:complications*
D009020:Morphine; D003000:Clonidine