[Significance of histologic bone marrow evaluation in diagnosis of chronic granulocytic leukemia. I. Reticulin fibrosis].
The aim of the study was the evaluation of bone marrow reticulin fibrosis in non-treated patients suffering from chronic granulocytic leukaemia (cgl). We have examined 40 patients (19 female and 21 male, average age 41.2 years) with chronic phase, Ph'-positive cgl. Reticulin fibrosis grade I and II (according to Dekmezian and co.) was detected in 47.5% of patients and grade III and IV in 42.5%. Statistically significant correlation was found between reticulin fibrosis intensity and spleen size, platelets count and Sokal index. We believe that reticulin fibrosis assessment is of prognostic value.
Kliniki Hematologii I.Ch.W. AM im. K. Marcinkowskiego, Poznaniu.
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Komarnicki
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Rasińska
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Woźny
D000293:Adolescent; D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D005355:Fibrosis; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011379:Prognosis; D012155:Reticulin / Q000032:analysis*; D013154:Spleen / Q000473:pathology
D012155:Reticulin
Znaczenie oceny histologicznej szpiku w diagnostyce przewlekłej białaczki szpikowej. I. Włóknienie retikulinowe.