Rest technetium 99m-sestamibi tomoscintigraphy in hibernating myocardium.
The myocardial uptake of rest-injected technetium 99m sestamibi on single-photon-emission computed tomographic images was assessed in 25 patients. All had an area of myocardial dysfunction that could be related to a coronary artery stenosis. None of the patients had clinical evidence of a myocardial infarction. Three months after revascularization, viability was demonstrated by contrast angiography and center-line analysis in 21 (78%) of the 27 formerly hibernating territories. Among these, none had a transmural defect, and 38% had a normal technetium 99m-sestamibi uptake. The four transmural preoperative defects were located in territories without viability. Eight of the 9 territories that were normal at scintigraphy proved to be viable postoperatively. It is concluded that as long as some residual technetium 99m-sestamibi uptake is present, viable myocardium is also present.
Department of Nuclear Medicine, Centre Jean Perrin, Clermont-Ferrand, France.
J C
JC
Maublant
B
B
Citron
J
J
Lipiecki
D
D
Mestas
P
P
Bailly
A
A
Veyre
C
C
de Riberolles
J
J
Ponsonnaille
D000368:Aged; D017023:Coronary Angiography / Q000379:methods / Q000706:statistics & numerical data; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017682:Myocardial Stunning / Q000000981:diagnostic imaging* / Q000628:therapy; D011446:Prospective Studies; D012146:Rest; D018709:Statistics, Nonparametric; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data
D017256:Technetium Tc 99m Sestamibi