[Cellular self-synchronization in a hepatocyte culture with antiphase fluctuations in the intensity of protein synthesis].
A part of suspension with isolated hepatocytes was cooled and then warmed to normal temperature. In cultures formed with such cells, antiphase oscillations of the protein synthesis rate were detected concerning control cultures from another part the same hepatocyte suspension. Oscillations of protein synthesis were observed in the mixed cultures formed with equal parts of antiphase subpopulations of hepatocytes. The experiments established cell interactions in vitro resulted in synchronization of protein synthesis oscillations in different cells the same population.
Brodskiĭ
V Ia
VIa
Nechaeva
N V
NV
Novikova
T E
TE
Gvazava
I G
IG
Fateeva
V I
VI
D000818:Animals; D002478:Cells, Cultured; D007930:Leucine / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D010507:Periodicity; D014176:Protein Biosynthesis; D051381:Rats; D013696:Temperature; D014316:Tritium
D014316:Tritium; D007930:Leucine
Samosinkhronizatsiia kletok v kul'ture gepatotsitov s protivofaznymi kolebaniiami intensivnosti sinteza belka.