[Loratadine versus terfenadine in perennial allergic rhinitis: ability to inhibit skin response].
We studied 104 medical student from the UANL, with symptoms of perenneal allergic rhinitis, including only 30 patients for this study; seven patients with loratadin 10 mg, eight with loratadine 20 mg and 15 with terfenadine 120 mg/day/21 days, 20 mg of loratadine and 120 mg of terfenadine demonstrated significant decrease of the symptoms (P). Two patients had collateral effects with terfenadine, but terfenadine were more effective than the loratadine in the reduction of the skin reactivity.
Centro Regional para el Tratamiento y la Prevención de las Enfermedades Alérgicas, UANL, Hospital Universitario, Monterrey, México.
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JI
Canseco Villarreal
D000293:Adolescent; D000328:Adult; D004334:Drug Administration Schedule; D006801:Humans; D017336:Loratadine / Q000627:therapeutic use*; D012221:Rhinitis, Allergic, Perennial / Q000150:complications / Q000188:drug therapy*; D012867:Skin / Q000187:drug effects / Q000276:immunology; D016593:Terfenadine / Q000627:therapeutic use*
D017336:Loratadine; D016593:Terfenadine
Loratadina vs terfenadina en rinitis alérgica perenne: capacidad para inhibir la respuesta cutánea.