Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. I. Taxonomy, fermentation and biological activity.
Actinomycete culture LL-D37187 has been found to produce the new polyether antibiotic martinomycin. Taxonomic studies, including morphological, physiological, and cell wall chemistry analyses, revealed that culture LL-D37187 is a novel streptomycete species, and the proposed name is Streptomyces salvialis. Martinomycin exhibits activity against the Southern Army Worm (Spodoptera eridania) and Gram-positive bacteria.
Bernan
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VS
Natural Products Research Section, American Cyanamid Company, Pearl River, NY 10965.
Montenegro
D A
DA
Goodman
J J
JJ
Alluri
M R
MR
Carter
G T
GT
Abbanat
D R
DR
Pearce
C J
CJ
Maiese
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WM
Greenstein
M
M
D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001156:Artemia / Q000187:drug effects; D004987:Ethers / Q000494:pharmacology; D005285:Fermentation; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007306:Insecticides / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning; D015394:Molecular Structure; D018411:Spodoptera; D013302:Streptomyces / Q000145:classification / Q000378:metabolism* / Q000648:ultrastructure
D000900:Anti-Bacterial Agents; D004987:Ethers; D007306:Insecticides; C091815:martinomycin