Hypertonic saline prehydration in patients undergoing transurethral resection of the prostate under spinal anaesthesia.
Thirty-three patients undergoing elective transurethral resection of the prostate were allocated randomly to receive either 0.9% isotonic saline 7 ml kg-1 (16 patients), or 3% hypertonic saline 7 ml kg-1 (17 patients) as a preload before spinal anaesthesia. After spinal anaesthesia, the incidence of systolic arterial pressure < 75% of control value was greater in the normal saline group than in the hypertonic saline group. Also, the mean dose of phenylephrine required to maintain arterial pressure > 75% of the baseline value was significantly greater in the normal saline group than in the hypertonic saline group.
Department of Anesthesiology, American University of Beirut, Lebanon.
A
A
Baraka
S
S
Taha
M
M
Ghabach
A
A
Sibaii
A
A
Nader
M
M
Matta
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000775:Anesthesia, Spinal; D001794:Blood Pressure / Q000502:physiology; D005440:Fluid Therapy; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007552:Isotonic Solutions; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011468:Prostatectomy; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage*; D012964:Sodium / Q000097:blood; D012965:Sodium Chloride / Q000008:administration & dosage
D007552:Isotonic Solutions; D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride; D012964:Sodium