Confirmation of 9q34 as the chromosomal site of the human lipocalin LCN1 gene.
The gene encoding the lipocalin LCN1 was previously assigned to human chromosome 8q24 by fluorescence in situ hybridization of a genomic DNA fragment and to 9q34 by in situ hybridization of a radiolabeled cDNA fragment of LCN1. To resolve this discrepancy, we used hamster x human hybrid cells for polymerase chain reaction experiments. These investigations confirmed the localization of LCN1 on chromosome 9.
Garvan Institute of Medical Research, St. Vincent Hospital, Darlinghurst, Australia.
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Herzog
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Baumgartner
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D000818:Animals; D002352:Carrier Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D002898:Chromosomes, Human, Pair 8; D002899:Chromosomes, Human, Pair 9; D006224:Cricetinae; D017931:DNA Primers; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D054835:Lipocalin 1; D016133:Polymerase Chain Reaction; D012471:Salivary Proteins and Peptides / Q000235:genetics*
D002352:Carrier Proteins; D017931:DNA Primers; C518443:LCN1 protein, human; D054835:Lipocalin 1; D012471:Salivary Proteins and Peptides