Intracranial iotrolan distribution following cervical myelography. Postmyelographic registration of adverse effects, psychometric assessment and electroencephalographic recording.
Following iotrolan cervical myelography 14 consecutive patients were evaluated with respect to intracranial contrast distribution and elimination, side effects, EEG-changes and psychometric assessments. The contrast medium is distributed in the subarachnoid space, in the ventricles and finally extracellularly in the cortex. Headache was the most prevalent side effect, occurring in half of the patients, 43% of "severe" grade. Eight patients showed mild nonspecific EEG-changes and all patients showed neuropsychologic disturbances.
Department of Diagnostic Radiology, Vejle Hospital, Denmark.
B
B
Fiirgaard
H H
HH
Madsen
U
U
Svare
F B
FB
Eriksen
T
T
Skjødt
I
I
Zeeberg
D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D003287:Contrast Media / Q000009:adverse effects*; D004569:Electroencephalography / Q000187:drug effects*; D005260:Female; D006261:Headache / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D009192:Myelography; D011581:Psychological Tests; D013997:Time Factors; D014283:Triiodobenzoic Acids / Q000009:adverse effects*
D003287:Contrast Media; D014283:Triiodobenzoic Acids; C033300:iotrolan