Investigation of NS0 cell metabolic behavior in monoclonal antibody producing clones.
Bibila
T
T
Merck Research Laboratories, Rahway, New Jersey 07065.
Ranucci
C
C
Glazomitsky
K
K
Buckland
B
B
Aunins
J
J
D000641:Ammonia / Q000378:metabolism; D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D002470:Cell Survival; D003470:Culture Media; D046508:Culture Techniques / Q000379:methods*; D004734:Energy Metabolism; D005786:Gene Expression Regulation / Q000187:drug effects; D005822:Genetic Vectors / Q000187:drug effects; D005947:Glucose / Q000378:metabolism; D005974:Glutamate-Ammonia Ligase / Q000235:genetics / Q000378:metabolism; D007773:Lactates / Q000378:metabolism; D019344:Lactic Acid; D008717:Methionine Sulfoximine / Q000494:pharmacology; D051379:Mice; D009994:Osmolar Concentration; D010954:Plasmacytoma / Q000473:pathology*; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis*; D014407:Tumor Cells, Cultured
D000911:Antibodies, Monoclonal; D003470:Culture Media; D007773:Lactates; D011993:Recombinant Fusion Proteins; D008717:Methionine Sulfoximine; D019344:Lactic Acid; D000641:Ammonia; D005974:Glutamate-Ammonia Ligase; D005947:Glucose