Identification of alcaligin as the siderophore produced by Bordetella pertussis and B. bronchiseptica.
The siderophores produced by iron-starved Bordetella pertussis and B. bronchiseptica were purified and were found to be identical. Using mass spectrometry and proton nuclear magnetic resonance, we determined that the siderophore produced by these organisms was identical to alcaligin, a siderophore produced by Alcaligenes denitrificans.
Department of Chemistry and Biochemistry, Massey University, Palmerston North, New Zealand.
C H
CH
Moore
L A
LA
Foster
D G
DG
Gerbig
D W
DW
Dyer
B W
BW
Gibson
D000421:Alcaligenes / Q000737:chemistry; D016950:Bordetella bronchiseptica / Q000737:chemistry*; D001886:Bordetella pertussis / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004305:Dose-Response Relationship, Drug; D006877:Hydroxamic Acids; D007501:Iron / Q000378:metabolism; D013058:Mass Spectrometry; D017262:Siderophores / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D006877:Hydroxamic Acids; D017262:Siderophores; C092056:alcaligin; D007501:Iron