[Significance of histologic bone marrow evaluation in diagnosis of chronic granulocytic leukemia. I. Reticulin fibrosis].
The aim of the study was the evaluation of bone marrow reticulin fibrosis in non-treated patients suffering from chronic granulocytic leukaemia (cgl). We have examined 40 patients (19 female and 21 male, average age 41.2 years) with chronic phase, Ph'-positive cgl. Reticulin fibrosis grade I and II (according to Dekmezian and co.) was detected in 47.5% of patients and grade III and IV in 42.5%. Statistically significant correlation was found between reticulin fibrosis intensity and spleen size, platelets count and Sokal index. We believe that reticulin fibrosis assessment is of prognostic value.
Komarnicki
M
M
Kliniki Hematologii I.Ch.W. AM im. K. Marcinkowskiego, Poznaniu.
Rasińska
M
M
Woźny
T
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D005355:Fibrosis; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011379:Prognosis; D012155:Reticulin / Q000032:analysis*; D013154:Spleen / Q000473:pathology
D012155:Reticulin
Znaczenie oceny histologicznej szpiku w diagnostyce przewlekłej białaczki szpikowej. I. Włóknienie retikulinowe.