Design of symmetry-based, peptidomimetic inhibitors of human immunodeficiency virus protease.
Kempf
D J
DJ
Pharmaceutical Products Division, Abott Laboratories, Abott Park, Illinois 60064.
D000595:Amino Acid Sequence; D001665:Binding Sites; D015195:Drug Design; D016333:HIV Protease / Q000737:chemistry* / Q000378:metabolism; D017320:HIV Protease Inhibitors / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D015497:HIV-1 / Q000187:drug effects / Q000201:enzymology*; D006860:Hydrogen Bonding; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D011485:Protein Binding; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
D017320:HIV Protease Inhibitors; D010455:Peptides; D016333:HIV Protease