[Deletion (7)(p11p15): an infrequent abnormality in blast crisis in chronic myeloid leukemia].
We report a patient with chronic myelocytic leukaemia (CML) in blastic crisis with a del (7) (p11 p15) in addition to the Philadelphia chromosome. A potential relationship between the presence of this deletion and the therapy in chronic phase is suggested.
Servicio de Genética Médica, Hospital Ramón y Cajal, Madrid.
M
M
Resino
M T
MT
Ferro
J
J
García-Laraña
J M
JM
García-Sagredo
P
P
Cabello
A
A
López-Yarto
C
C
San Román
D001752:Blast Crisis / Q000235:genetics* / Q000473:pathology; D002872:Chromosome Deletion; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged
Deleción (7) (p11p15): una anomalía infrecuente en la crisis blástica de la leucemia mieloide crónica.