[The inhibitory action of a saccharide derivative on a calcium channel in the oocyte of Xenopus].
Endogenous calcium channels of Xenopus oocyte membrane do not fit with pharmacological classification of calcium channels. The present study demonstrates that the saccharidic derivate, OC8-MAGlu-MAGlu, has potent inhibitory effect on this channel activity.
Laboratoire de Neurobiologie Cellulaire, Université de Picardie Jules Verne, Faculté des Sciences, Amiens, France.
A
A
Lahyani
F
F
Fournier
P
P
Navarre
G
G
Charpentier
D
D
Marlot
P
P
Vanlemmens
G
G
Ronco
P
P
Villa
G
G
Brule
D000818:Animals; D002121:Calcium Channel Blockers / Q000138:chemical synthesis* / Q000494:pharmacology; D004187:Disaccharides / Q000138:chemical synthesis* / Q000494:pharmacology; D009865:Oocytes / Q000187:drug effects / Q000378:metabolism*; D014981:Xenopus
C091663:3-O-octyl-1,2-O-isopropylideneglucofuranosyl-(6-3')-1,2-O-isopropylideneglucofuranose; D002121:Calcium Channel Blockers; D004187:Disaccharides
Mise en évidence de l'action inhibitrice d'un dérivé saccharidique sur le canal calcique de l'ovocyte de Xénope.