Identification of a specific mammalian melanocortin receptor antagonist.
Division of Endocrinology, Diabetes, Metabolism and Molecular Medicine, New England Medical Center, Boston, Massachusetts 02111.
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Entwistle
D000067956:Adenylyl Cyclase Inhibitors; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002460:Cell Line; D005576:Colforsin / Q000494:pharmacology; D000242:Cyclic AMP / Q000378:metabolism; D004789:Enzyme Activation / Q000187:drug effects; D006801:Humans; D007668:Kidney; D008322:Mammals; D008546:Melanoma, Experimental; D051379:Mice; D051381:Rats; D011979:Receptors, Pituitary Hormone / Q000037:antagonists & inhibitors* / Q000096:biosynthesis / Q000378:metabolism; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000378:metabolism; D014162:Transfection; D014407:Tumor Cells, Cultured; D000521:alpha-MSH / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors* / Q000494:pharmacology
D000067956:Adenylyl Cyclase Inhibitors; D011979:Receptors, Pituitary Hormone; D011994:Recombinant Proteins; C091589:alpha-MSH (6-11)amide, D-tryptophyl(7)-D-phenylalanyl(10)-; D005576:Colforsin; D000521:alpha-MSH; C029446:MSH receptor; D000242:Cyclic AMP; D000262:Adenylyl Cyclases