[Lipoprotein Z].
The term lipoprotein Z (remnant-like particles) refers to lipoproteins that do not have an immunoaffinity to gel mixture of anti-apo A-I and apo B100 monoclonal antibodies (JI-H antibody). Lp Z is enriched in apo E and cholesterol esters. Quantification of this lipoprotein provides a useful index of atherogenic chyromicron and VLDL remnant particles. Serum concentration of this lipoprotein is well correlated to serum triglycerides in normal subjects and patients with hypertriglyceridemia, and to serum LDL-cholesterol in normal subjects. The normal range of this lipoprotein is below 5 mg/dl and the increased serum concentration is often observed in ischemic heart disease, diabetes mellitus, hypertriglyceridemia and fatty liver.
First Department of Internal Medicine, School of Medicine, Hiroshima University.
G
G
Kajiyama
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T
Otsuki
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Kawanishi
D003920:Diabetes Mellitus / Q000175:diagnosis; D006801:Humans; D015228:Hypertriglyceridemia / Q000175:diagnosis; D008074:Lipoproteins / Q000032:analysis; D017202:Myocardial Ischemia / Q000175:diagnosis; D012307:Risk Factors
D008074:Lipoproteins