[Partial portal vein and mesenteric vein thrombosis in familial protein S deficiency].
Protein S, a vitamin-K dependent glycoprotein is a cofactor of protein-C system, which acts as an inhibitor of the plasmatic coagulation. Protein-S congenital deficiency results in recurrent venous thromboses, atypical locations in portal and mesenteric veins are possible. In our patient the partial thrombosis of the portal vein was diagnosed by computed tomography and angiography. Small bowel ischaemia due to mesenteric vein thrombosis required segmental resection. Post-operatively the patient was heparinized and later phenprocoumon was applied to a long-term therapy.
Klinik und Poliklinik für Allgemeine Chirurgie, Klinikum Erfurt.
M
M
Seifert
U
U
Fleck
G
G
Vogel
C
C
Bätz
S
S
Basche
D000328:Adult; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D007421:Intestine, Small / Q000098:blood supply; D007511:Ischemia / Q000097:blood / Q000235:genetics / Q000601:surgery; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000097:blood / Q000235:genetics*; D008642:Mesenteric Veins / Q000601:surgery; D010644:Phenprocoumon / Q000008:administration & dosage; D011169:Portal Vein / Q000601:surgery; D011182:Postoperative Care; D018455:Protein S Deficiency / Q000097:blood / Q000235:genetics* / Q000601:surgery; D013927:Thrombosis / Q000097:blood / Q000235:genetics*; D014057:Tomography, X-Ray Computed
D006493:Heparin; D010644:Phenprocoumon
Partielle Pfortader- und Mesenterialvenenthrombose bei familiärem Protein-S-Mangel.