Vibrindole A, a metabolite of the marine bacterium, Vibrio parahaemolyticus, isolated from the toxic mucus of the boxfish Ostracion cubicus.
The EtOAc extract of the whole culture medium of Vibrio parahaemolyticus, which inhabits the toxic mucus of the box fish Ostracion cubicus, afforded a new indole-derived natural product, vibrindole A [1], along with some known cyclic dipeptides and indoles. The structure of 1 was determined by analysis of its physicochemical characteristics.
School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv, Israel.
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Bell
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Carmeli
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D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001412:Bacillus subtilis / Q000187:drug effects; D000431:Ethanol; D005397:Fish Venoms; D005399:Fishes / Q000382:microbiology*; D007211:Indoles / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D015394:Molecular Structure; D009092:Mucous Membrane / Q000382:microbiology; D013210:Staphylococcus / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D014736:Vibrio parahaemolyticus / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D005397:Fish Venoms; D007211:Indoles; C091983:vibrindole A; D000431:Ethanol