[The role of serotonin and noradrenaline in regulating the motor activity of the chick amnion].
In experiments on chick embryos from various age groups, studies have been made of the effect of a blockader of serotonin receptors--cyproheptadine--and blockader of adrenoreceptors--propranolol--on rhythmic activity of the amnion in vivo after injection of the substances into amniotic fluid. Stimulating effect of propranolol from the 9th to the 19th day of incubation and inhibitory effect of cyproheptadine from the 5th to the 19th day of incubation were revealed. These results indicate the existence of serotonin and noradrenaline in the amniotic fluid of chick embryo. High performance liquid chromatography directly confirmed this conclusion.
Nechaeva
M V
MV
Zhurkovich
I K
IK
Kovrov
N G
NG
Turpaev
T M
TM
D000650:Amnion / Q000187:drug effects / Q000502:physiology*; D000653:Amniotic Fluid / Q000737:chemistry / Q000187:drug effects / Q000502:physiology; D000818:Animals; D002642:Chick Embryo; D002851:Chromatography, High Pressure Liquid; D003533:Cyproheptadine / Q000494:pharmacology; D004837:Epinephrine / Q000032:analysis; D005324:Fetal Movement / Q000187:drug effects; D009638:Norepinephrine / Q000032:analysis / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D012701:Serotonin / Q000032:analysis / Q000502:physiology*; D013997:Time Factors
D003533:Cyproheptadine; D012701:Serotonin; D011433:Propranolol; D009638:Norepinephrine; D004837:Epinephrine
Rol' serotonina i noradrenalina v reguliatsii dvigatel'noĭ aktivnosti amniona kurinogo zarodysha.