Copper deficiency-induced anemia and neutropenia secondary to intestinal malabsorption.
A patient with a history of partial gastrectomy presented with severe anemia, neutropenia, intestinal malabsorption, and was found to be severely copper-deficient. The anemia and neutropenia corrected promptly with the administration of intravenous cupric chloride. This case suggests that partial gastrectomy with or without intestinal malabsorption can result in copper deficiency and should be considered in differential diagnosis of severe anemia and neutropenia.
Department of Medicine, University of California, San Diego 92103-8421.
B A
BA
Hayton
H E
HE
Broome
R C
RC
Lilenbaum
D000328:Adult; D000740:Anemia / Q000209:etiology*; D003300:Copper / Q000172:deficiency*; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects; D006801:Humans; D008286:Malabsorption Syndromes / Q000150:complications*; D009503:Neutropenia / Q000209:etiology*
D003300:Copper