Critical illness neuromuscular disease in children manifested as ventilatory dependence.
Four children with prolonged dependency on a ventilator were found to have reversible quadriparesis, muscle wasting, and hyporeflexia after 8 to 20 days of assisted ventilation for life-threatening sepsis or respiratory failure. Critical illness neuromuscular disease, which was recently recognized as a distinct clinical syndrome in adults, may also be manifested in children by prolonged ventilatory dependency.
Sheth
R D
RD
Department of Neurology, West Virginia University Health Sciences Center, Morgantown 26506-9180.
Pryse-Phillips
W E
WE
Riggs
J E
JE
Bodensteiner
J B
JB
D000293:Adolescent; D001249:Asthma / Q000150:complications; D002648:Child; D016638:Critical Illness; D005260:Female; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000150:complications; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000209:etiology; D011649:Pulmonary Alveolar Proteinosis / Q000150:complications; D012131:Respiratory Insufficiency / Q000175:diagnosis* / Q000209:etiology; D012772:Shock, Septic / Q000150:complications; D013577:Syndrome; D015300:Ventilator Weaning; D012122:Ventilators, Mechanical