Global stability in a delayed partial differential equation describing cellular replication.
Here we consider the dynamics of a population of cells that are capable of simultaneous proliferation and maturation. The equations describing the cellular population numbers are first order partial differential equations (transport equations) in which there is an explicit temporal retardation as well as a nonlocal dependence in the maturation variable due to cell replication. The behavior of this system may be considered along the characteristics, and a global stability condition is proved.
Mackey
M C
MC
Department of Physiology, McGill University, Montreal, Canada.
Rudnicki
R
R
D000818:Animals; D002453:Cell Cycle; D002455:Cell Division; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D008962:Models, Theoretical