Clinical investigation of the antidepressant effectiveness of hypericum.
To date, 25 controlled therapy studies have investigated the antidepressive effectiveness of hypericum extracts. A total of 1592 treatment cases have been included. The dosage was typically 300 to 900 mg total extract daily; the therapy duration was 2 to 6 weeks. Fifteen studies were performed comparing hypericum extracts with placebo, 10 studies as comparative studies. This paper presents an overview of their results.
Harrer
G
G
Institut für Forensische Psychiatrie, Universität, Salzburg, Austria.
Schulz
V
V
D000928:Antidepressive Agents / Q000627:therapeutic use*; D006801:Humans; D020902:Hypericum; D010569:Perylene / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D011794:Quercetin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014966:Xanthenes / Q000627:therapeutic use*
D000928:Antidepressive Agents; D010936:Plant Extracts; D014966:Xanthenes; D010569:Perylene; D011794:Quercetin