Lipoprotein modification: cellular mechanisms.
Oxidatively damaged LDL may be of pivotal importance in atherogenesis. This review focuses on the cellular pathways involved in LDL oxidation in vitro, the biological properties of oxidized LDL, and the implications of these findings for the role of LDL oxidation in the development of atherosclerosis.
Chait
A
A
Department of Medicine, University of Washington, Seattle.
Heinecke
J W
JW
D000818:Animals; D001158:Arteries / Q000378:metabolism / Q000473:pathology; D001161:Arteriosclerosis / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism*; D008077:Lipoproteins, LDL / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000378:metabolism* / Q000473:pathology; D010084:Oxidation-Reduction
D008074:Lipoproteins; D008077:Lipoproteins, LDL