The clonal nature of mediastinal germ cell tumors and acute myelogenous leukemia. A case report and review of the literature.
The clonal identity of a mediastinal germ cell malignant tumor and acute myelogenous leukemia is described in an 11-year-old boy in whom both tumors presented simultaneously. The relationship between these two histologically distinct malignancies is discussed in relation to this patient and 34 previously reported patients.
Gwynne Hazen Cherry Memorial Laboratories, UCLA School of Medicine 90024.
K
K
Woodruff
N
N
Wang
W
W
May
E
E
Adrone
C
C
Denny
S A
SA
Feig
D002648:Child; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008479:Mediastinal Neoplasms / Q000235:genetics*; D009373:Neoplasms, Germ Cell and Embryonal / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics*