[The incidence of post-thrombotic syndrome].
To evaluate the clinical and socio-economic importance of the postthrombotic syndrome (PTS), the following epidemiologic parameters are to be known: The incidence of deep vein thrombosis (DVT) in the population, the incidence of PTS after DVT, the prevalence of the PTS, the socio-medical consequences and the mortality. The DVT-incidence in the literature is about 3/1000 per year in the adult population. In our own follow-up study we found a global PTS-incidence of 40% (10% with, 30% without ulcer) 13 years after DVT. The PTS-incidence was correlated with the initial DTV-extent. The risk of PTS after 3- and 4-level DVT is significantly reduced by a successful fibrinolysis in the acute stage (p = 0.01). The mortality of patients with PTS is 3 times higher than in the population. 4% of the patients with PTS get disabled. To our knowledge an adequate study with direct assessment of the PTS-prevalence does not exist, but the PTS-prevalence can be deduced from large epidemiologic studies, such as the Basel-Study, in which the global chronic venous insufficiency is assessed. It amounts in the adult population between 0.5 to 1% for the PTS with and 3 to 5% for the PTS without ulcer.
Eichlisberger
R
R
Abteilung Angiologie, Universitätskliniken Basel, Schweiz.
Widmer
M T
MT
Frauchiger
B
B
Widmer
L K
LK
Jäger
K
K
D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D011186:Postphlebitic Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000453:epidemiology*; D012008:Recurrence; D013557:Switzerland
D000925:Anticoagulants
Zur Häufigkeit des postthrombotischen Syndroms.