A semi-micro method for fibrinogen determination essentially unaffected by turbidity.
A semi-micro method (BR BLUE) is presented using Coomassie Brilliant Blue G-250 color reagent for the determination of fibrinogen on potentially turbid specimens. It is compared with the reference Clauss method using the automated MLA Electra 1000C Automatic Coagulation Timer and the semi-automated Mechrolab Clot Timer. Correlation is excellent (r = 0.97). The BR BLUE method is also seen to be reasonably precise and linear.
Carroll
W E
WE
Department of Pathology, Santa Barbara Cottage Hospital, CA 93105.
Jackson
R D
RD
Herring
D J
DJ
Eichould
A B
AB
MacArthur
B M
BM
D000328:Adult; D000368:Aged; D005260:Female; D005340:Fibrinogen / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012394:Rosaniline Dyes
D012394:Rosaniline Dyes; D005340:Fibrinogen; C004692:coomassie Brilliant Blue