[A hormonally-active form of vitamin D3--1,25-dihydroxyvitamin D3--an inhibitor of leukocyte lipoxygenase].
The effect of the hormonally active vitamin D3 formulation on the activity of porcine leukocyte lipoxygenase was studied. The rate of enzyme inhibition was vitamin dose-dependent and increased if pH values raised, while the vitamin inhibitory effect was decreased as the content of linoleic acid used as a substrate was increased.
Bondarenko
L B
LB
Kharchenko
O V
OV
Butovich
I A
IA
D000818:Animals; D002117:Calcitriol / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D007962:Leukocytes / Q000187:drug effects* / Q000201:enzymology; D016859:Lipoxygenase Inhibitors / Q000494:pharmacology*; D013552:Swine
D016859:Lipoxygenase Inhibitors; D002117:Calcitriol
Gormonal'no-aktivnaia forma vitamina D3--1,25-dioksivitamin D3-- ingibitor leĭkotsitarnoĭ lipoksigenazy.