Characterization of the gene encoding carbonic anhydrase I from the pigtail macaque.
The structure of the gene encoding carbonic anhydrase I (CA I) was determined for the pigtail macaque Macaca nemestrina. When the deduced amino-acid sequence was compared with those of five other primates, four non-primate mammals and a turtle, seven residues were found to be unique and invariant to all of the CA I sequences. A scheme is presented for the probable evolutionary order of the six polymorphic nucleotide changes found in the coding regions of the CA I locus of pigtail macaques.
Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109-0618.
P J
PJ
Hopkins
N C
NC
Bergenhem
P J
PJ
Venta
D
D
Hewett-Emmett
R E
RE
Tashian
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002256:Carbonic Anhydrases / Q000235:genetics*; D004247:DNA; D006801:Humans; D008254:Macaca nemestrina; D051379:Mice; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid; D014426:Turtles
D004247:DNA; D002256:Carbonic Anhydrases