Choose your partner: chromosome pairing in yeast meiosis.
Premeiotic association of homologous chromosomes in the yeast, Saccharomyces cerevisiae has been shown, by means of fluorescent in situ hybridization (FISH). Time course and mutant studies show that the premeiotic associations are disrupted upon entry into meiosis, to be reestablished shortly before synapsis. The data are consistent with a model in which multiple, unstable interactions bring homologues together, prior to stable joining by recombination.
Department of Genetics, Hebrew University of Jerusalem, Givat Ram, Israel.
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Klein
D015825:Chromosomes, Fungal / Q000235:genetics*; D008540:Meiosis; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics*