Antibacterial and antifungal sulfated alkane and alkenes from the hepatopancreas of the ascidian Halocynthia roretzi.
Four new antibacterial and antifungal sulfates, 2,6-dimethylheptyl sulfate [1], (4Z,7Z)-4,7-decadienyl sulfate [2], (4Z,7E)-4,7-decadienyl sulfate [3], and (3Z,6Z)-3,6,9-decatrienyl sulfate [4], have been isolated from the hepatopancreas of the ascidian Halocynthia roretzi. The structures were determined by spectral analysis.
Tsukamoto
S
S
Fusetani Biofouling Project, Exploratory Research for Advanced Technology (ERATO), Research Development Corporation of Japan (JRDC), Yokohama.
Kato
H
H
Hirota
H
H
Fusetani
N
N
D000473:Alkanes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000475:Alkenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004064:Digestive System / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009090:Mucorales / Q000187:drug effects; D013329:Structure-Activity Relationship; D013464:Sulfuric Acids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D014561:Urochordata; D014733:Vibrio / Q000187:drug effects
D000473:Alkanes; D000475:Alkenes; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D013464:Sulfuric Acids