Sulfate conjugates of catecholamines in the allantoic fluid of the chicken embryo.
In addition to free dopamine (DA), norepinephrine (NE), and epinephrine (E), the allantoic fluid of the 13-day-old chicken embryo contains sulfate conjugates of these three catecholamines (CAs). The concentration of DA sulfate is relatively low, while NE and E sulfates occur at levels similar to those of the free fractions. The comparatively low concentration of free CAs in the amniotic fluid, seen in a previous study, is confirmed. However, the amniotic barrier for sulfated CAs is much stronger, possibly absolute. Though some technical difficulties remain to be resolved, the chicken embryo may become a useful model for the study of the prenatal functions of CA conjugates.
Department of Anatomy, Pathology and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
T S
TS
Gill
S
S
Porta
B
B
Nibbio
A
A
Epple
D000482:Allantois / Q000737:chemistry*; D000818:Animals; D002642:Chick Embryo / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004298:Dopamine / Q000302:isolation & purification / Q000378:metabolism*; D004837:Epinephrine / Q000302:isolation & purification / Q000378:metabolism*; D009638:Norepinephrine / Q000302:isolation & purification / Q000378:metabolism*
D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine