Potential anxiolytic agents. Pyrido[1,2-a]benzimidazoles: a new structural class of ligands for the benzodiazepine binding site on GABA-A receptors.
Drug Discovery, R. W. Johnson Pharmaceutical Research Institute, Spring House, Pennsylvania 19477.
B E
BE
Maryanoff
W
W
Ho
D F
DF
McComsey
A B
AB
Reitz
P P
PP
Grous
S O
SO
Nortey
R P
RP
Shank
B
B
Dubinsky
R J
RJ
Taylor
J F
JF
Gardocki
D000818:Animals; D014151:Anti-Anxiety Agents / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology*; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology*; D001569:Benzodiazepines / Q000378:metabolism*; D001665:Binding Sites; D007700:Kinetics; D051379:Mice; D011725:Pyridines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D011963:Receptors, GABA-A / Q000187:drug effects* / Q000378:metabolism*; D013329:Structure-Activity Relationship
D014151:Anti-Anxiety Agents; D001562:Benzimidazoles; D011725:Pyridines; D011963:Receptors, GABA-A; D001569:Benzodiazepines