Glutaraldehyde: current status and uses.
Glutaraldehyde (pentanedial) is a dialdehyde that displays potent bactericidal, fungicidal, mycobactericidal, sporicidal, and virucidal activity. Pertinent to its activity is its interaction with amino groups in proteins and enzymes, but this simplistic statement masks the manner in which it inactivates various types of microorganisms. Notwithstanding its toxicity for medical staff, glutaraldehyde remains an invaluable compound for high-level disinfection purposes in endoscopy units.
Russell
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Welsh School of Pharmacy, University of Wales College of Cardiff.
D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D005976:Glutaral / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D017053:Infection Control; D008826:Microbial Sensitivity Tests; D013171:Spores, Bacterial / Q000187:drug effects; D013242:Sterilization; D014780:Viruses / Q000187:drug effects
D005976:Glutaral