Therapeutic support of the patient with thrombocytopenia.
This article provides an update on the methods of collection, preservation, storage, and administration of platelet concentrates. The current indications for platelet transfusions are reviewed, and current knowledge concerning alloimmunization and its prevention is summarized. In addition, the ongoing controversies related to prophylactic administration of platelets versus therapeutic administration are reviewed.
Brown University School of Medicine, Rhode Island Hospital, Providence.
P B
PB
Rintels
R M
RM
Kenney
J P
JP
Crowley
D001792:Blood Platelets; D001855:Bone Marrow Diseases / Q000517:prevention & control / Q000628:therapy; D000075202:Contraindications; D016207:Cytokines / Q000627:therapeutic use; D006410:Hematopoiesis; D006470:Hemorrhage / Q000517:prevention & control; D006801:Humans; D017713:Platelet Transfusion; D013921:Thrombocytopenia / Q000628:therapy*
D016207:Cytokines