Hypervitaminosis A in two hemodialysis patients.
We present two cases of hemodialysis patients developing vitamin A toxicity related to excessive consumption of nutritional supplements containing large quantities of vitamin A. In one patient, severe hypercalcemia was the lone presenting sign; in the other, hypercalcemia was associated with unusual neurologic manifestations. We will discuss the reason why hemodialysis patients are at special risk for the development of hypervitaminosis A and review the mechanism leading to the associated hypercalcemia.
Fishbane
S
S
Division of Nephrology, Winthrop-University Hospital, Mineola, NY 11501.
Frei
G L
GL
Finger
M
M
Dressler
R
R
Silbiger
S
S
D000328:Adult; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006986:Hypervitaminosis A / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis