Anti-human immunodeficiency virus and anti-hepatitis-B virus activities and toxicities of the enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine and their 5-fluoro analogues in vitro.
BioChem Therapeutic Inc., Laval, Québec, Canada.
T S
TS
Mansour
H
H
Jin
W
W
Wang
E U
EU
Hooker
C
C
Ashman
N
N
Cammack
H
H
Salomon
A R
AR
Belmonte
M A
MA
Wainberg
D000818:Animals; D000998:Antiviral Agents / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity*; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity; D015497:HIV-1 / Q000187:drug effects*; D006515:Hepatitis B virus / Q000187:drug effects*; D006801:Humans; D019259:Lamivudine; D007963:Leukocytes, Mononuclear / Q000821:virology; D008114:Liver Neoplasms, Experimental / Q000821:virology; D013237:Stereoisomerism; D013872:Thionucleosides / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity*; D016047:Zalcitabine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity
D000998:Antiviral Agents; D013872:Thionucleosides; D003841:Deoxycytidine; C081758:2'-deoxy-5-fluoro-3'-thiacytidine; D019259:Lamivudine; D016047:Zalcitabine