Probing to bone in infected pedal ulcers. A clinical sign of underlying osteomyelitis in diabetic patients.
OBJECTIVE
To assess a bedside technique for diagnosing osteomyelitis.


METHODS
We prospectively assessed infected pedal ulcers for detectable bone by probing with a sterile, blunt, stainless steel probe. We then examined the relationship between detection of bone and the presence or absence of osteomyelitis that was defined histopathologically and/or clinically.


METHODS
A tertiary care center.


METHODS
Seventy-five hospitalized diabetic patients with a total of 76 infected foot ulcers were studied.


RESULTS
Osteomyelitis was diagnosed in 50 instances (66%) and was excluded in 26 instances. Bone was detected by probing in 33 of 50 ulcers with contiguous osteomyelitis; in contrast, bone was probed in only four of 26 ulcers without contiguous osteomyelitis (P < .001). Bone detected on probing was visible in only three instances. Palpating bone on probing the pedal ulcer had a sensitivity of 66% for osteomyelitis, a specificity of 85%, a positive predictive value of 89%, and a negative predictive value of 56%.


CONCLUSIONS
Palpation of bone in the depths of infected pedal ulcers in patients with diabetes is strongly correlated with the presence of underlying osteomyelitis. If bone is palpated on probing, specialized roentgenographic and radionuclide tests to diagnose osteomyelitis are unnecessary. Probing for bone should be included in the initial assessment of all diabetic patients with infected pedal ulcers.
Grayson
M L
ML
Department of Medicine, New England Deaconess Hospital, Boston, Mass 02215.
Gibbons
G W
GW
Balogh
K
K
Levin
E
E
Karchmer
A W
AW
D000368:Aged; D001842:Bone and Bones / Q000473:pathology*; D003646:Debridement / Q000295:instrumentation / Q000379:methods*; D017719:Diabetic Foot / Q000150:complications* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology; D011446:Prospective Studies