Brainstem auditory-evoked potentials and neuropathologic correlates in 26 dogs with brain tumors.
Brainstem auditory-evoked potentials (BAEPs) were recorded from 26 dogs with intracranial neoplasia. The tumors were grouped according to their neuroanatomic location. Normal BAEPs were recorded from 12 dogs with cerebral (6/7), diencephalic (4/4), cerebellar (1/1), and multifocal tumors (1/5). Abnormal BAEPs were recorded from 14 dogs were cerebral (1/7), cerebellar/brainstem (4/4), brainstem (5/5), and multifocal tumors (4/5). Analysis of the multifocal neoplasms showed that alterations of BAEPs correlated with the degree of brainstem involvement. Overall, 13 of the 14 dogs with abnormal BAEPs had tumors involving the brainstem. The changes of the BAEP correlated with the extrinsic or intrinsic location of the tumor relative to the brainstem. The BAEP reflected the right, left, or median location of the tumor in 7 of the 14 abnormal recordings. In 1 dog, the BAEP was abnormal contralateral to the tumor side. A peripheral hearing disorder was excluded in most dogs based on the presence of peak I.
Clinic of Internal Medicine, Faculty of Veterinary Medicine, University of Munich, Germany.
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A
Fischer
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Obermaier
D000818:Animals; D001932:Brain Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D008297:Male