Increased phenotypic switching in strains of Candida albicans associated with invasive infections.
This study reports the rates of phenotypic switching in strains of Candida albicans isolated from superficial and invasive infections. Of 19 invasive strains, 68% showed switching activity, often at very high rates, compared with only 28% of 40 strains isolated from superficial sites (P = 0.004).
Public Health Laboratory, Countess of Chester Health Park, United Kingdom.
S
S
Jones
G
G
White
P R
PR
Hunter
D002176:Candida albicans / Q000472:pathogenicity*; D005260:Female; D006801:Humans; D010641:Phenotype; D014774:Virulence