[Studies on the early serodiagnosis of leptospirosis by dot-ELISA].
Thirty serum samples of patients with early leptospirosis from whom cultures of leptospira were positive were tested by dot-enzyme linked immunosorbent assay (dot-ELISA) and microscopical agglutination test (MAT). The results showed that the positive rate of dot-ELISA (40%) was higher than that of MAT (13.3%). One-hundred and ninety-eight serum samples from patients with clinical diagnosis of early leptospirosis were tested by dot-ELISA, MAT and blood culture. The results showed that the positive rate of dot-ELISA (64.6%) was higher than that of blood culture (15.2%) and MAT (14.1%). The longer the time of the illness, the lower the positive rate of the blood culture. However, the positive rate of dot-ELISA was stable in different stages of the illness.
Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing.
T
T
Lin
M
M
Shi
J
J
Long
D000372:Agglutination Tests; D003470:Culture Media; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D007919:Leptospira / Q000254:growth & development; D007922:Leptospirosis / Q000175:diagnosis*; D012698:Serologic Tests
D003470:Culture Media