An integrin-mobilferrin iron transport pathway in intestine and hematopoietic cells.
A pathway of iron transport not involving transferrin or transferrin receptors has been described as functioning in iron uptake into intestinal cells and in a hematopoietic cell line. Evidence was presented to show that it is mediated by a transmembrane protein (integrin) and a cytosolic protein (mobilferrin).
Wolf
G
G
Department of Nutritional Sciences, University of California, Berkeley.
Wessling-Resnick
M
M
D000818:Animals; D001693:Biological Transport, Active; D002352:Carrier Proteins / Q000378:metabolism*; D005293:Ferritins / Q000378:metabolism; D006413:Hematopoietic System / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D016023:Integrins / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000166:cytology; D017136:Ion Transport; D007501:Iron / Q000493:pharmacokinetics*; D033862:Iron-Binding Proteins
D002352:Carrier Proteins; D016023:Integrins; D033862:Iron-Binding Proteins; C085511:mobilferrin; D005293:Ferritins; D007501:Iron