[New pharmacological approach to therapy of perimenopausal meno-metrorrhagia. Vaginal use of progesterone].
The authors evaluate the effectiveness of a therapy based on natural progesterone to be employed as a vaginal cream in the treatment of meno-metrorrhagia in peri-menopause in 40 patients who were not prepared to consider surgery as a solution for their problems. In the polycentric out-patient study this new preparation has proved to be efficacious and to induce a regression of the endometrial hyperplasia in more than 90% of patients subject to five months' treatment.
Divisione di Ostetricia-Ginecologia, Ospedale Sacco, Milano.
L
L
Cipolla
R
R
Zagni
G
G
Giannetta
B
B
Ferrante
A
A
Soliani
D000328:Adult; D004714:Endometrial Hyperplasia / Q000188:drug therapy; D005260:Female; D006801:Humans; D008595:Menorrhagia / Q000188:drug therapy*; D008796:Metrorrhagia / Q000188:drug therapy*; D008875:Middle Aged; D017697:Premenopause; D011374:Progesterone / Q000008:administration & dosage*; D013997:Time Factors; D014622:Vaginal Creams, Foams, and Jellies
D014622:Vaginal Creams, Foams, and Jellies; D011374:Progesterone
Nuovo approccio farmacologico alla terapia delle meno-metrorragie peri-menopausali. Utilizzo del progesterone per via vaginale.