Microbiota of rapidly progressive periodontitis lesions in association with clinical parameters.
The microbial population in 73 rapidly progressive periodontitis (RPP) lesions in 10 young adults aged 25 to 35 years (5 males, 5 females) was studied in relation to the clinical parameters probing depth, bleeding on probing, and suppuration, which were recorded at the sampled sites. Porphyromonas gingivalis was found to predominate (26.7%) in 73 periodontal lesions with clinical probing depth > 6 mm, followed by Bacteroides forsythus (23.6%), and Prevotella intermedia (15.7%). The prevalence of P. gingivalis was 91.7%, Fusobacterium nucleatum, 90.4%; Streptococcus intermedius, 87.7%; and B. forsythus, 53.4%. Significant differences between bleeding index 0, 1, and 2 (P < 0.05) in frequency of detection were found for P. intermedia, Campylobacter concisus, Selenomonas sputigena, and Peptostreptococcus micros at bleeding sites and for Streptococcus sanguis, Actinobacillus actinomycetemcomitans, and B. forsythus (P < 0.001) at non-bleeding sites. Between suppurating and non-suppurating sites, significant differences (P < 0.05) in frequency of isolation were found for P. intermedia, Capnocytophaga ochracea, and A. actinomycetemcomitans at suppurating sites and for F. nucleatum at non-suppurating sites.
Department of Periodontology, School of Dental Medicine, University of Athens, Greece.
J J
JJ
Kamma
M
M
Nakou
F A
FA
Manti
D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D010520:Aggressive Periodontitis / Q000382:microbiology / Q000473:pathology; D000704:Analysis of Variance; D001439:Bacteroides / Q000302:isolation & purification; D002167:Campylobacter / Q000302:isolation & purification; D002206:Capnocytophaga / Q000302:isolation & purification; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000382:microbiology; D005260:Female; D016967:Fusobacterium nucleatum / Q000302:isolation & purification; D005884:Gingival Hemorrhage; D006801:Humans; D016013:Likelihood Functions; D016014:Linear Models; D008297:Male; D010462:Peptostreptococcus / Q000302:isolation & purification; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000382:microbiology / Q000473:pathology; D010518:Periodontitis / Q000382:microbiology* / Q000473:pathology*; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D018713:Prevotella intermedia / Q000302:isolation & purification; D018709:Statistics, Nonparametric; D013291:Streptococcus / Q000302:isolation & purification; D013298:Streptococcus sanguis / Q000302:isolation & purification; D013492:Suppuration