The development of a decision support system for the pathological diagnosis of human cerebral tumours based on a neural network classifier.
This study describes the use of a topological mapping system in the classification of cerebral tumours and the development of a decision support system based upon that classifier. Fourteen pathological parameters from two hundred primary cerebral tumours are presented as vectors to a topological map. The map, consisting of a grid of neurones, learns the features of each tumour by means of a shortest Euclidean distance algorithm, after which self adaptation of the neurons occurs. An LVQ algorithm performs the final classification. Study of the map reveals that it can correctly classify tumors following their malignancy potential and their cytogenesis. The decision support system uses the network at its core and helps not only in reaching a diagnosis but also in finding the optimal way to reach that diagnosis. The usefulness of such a mapping system lies in the field of education, clinical research and medically acceptable cost reduction.
Sieben
G
G
N. Goormaghtigh Institute of Pathology, University Hospital Ghent, Belgium.
Praet
M
M
Roels
H
H
Otte
G
G
Boullart
L
L
Calliauw
L
L
D000465:Algorithms; D001921:Brain / Q000473:pathology; D001931:Brain Mapping / Q000295:instrumentation*; D001932:Brain Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D003661:Decision Support Techniques; D005103:Expert Systems / Q000295:instrumentation; D006801:Humans; D016571:Neural Networks, Computer; D009474:Neurons / Q000473:pathology