[Effects of electroacupuncture on central and peripheral monoamine neurotransmitter in the course of protecting rat stress peptic ulcer].
The experimental Wistar rats were divided into two groups, the acupuncture group and the control group. Stress-induced gastric ulcer models were established by immersion of restrained rats in water. The results are as follows: 1. Stress-induced peptic ulceration was able to be protected with electroacupuncture. 2. Synthesis and decomposition of central and peripheral 5-HT in the electroacupunctured tats was inhibited. 3. The NE levels in the three brain regions (cortex, hypothalamus, brainstem) and blood were seen in the electroacupuncture group more than that in the control group, but the NE levels was smaller in the gastric tissue. 4. The higher levels of DA in the gastric tissue and blood were seen in the electroacupuncture group than in the control group. The results indicated that protecting rat stress ulceration with electroacupuncture was connected with monoamine neurotransmitter of centre and periphery.
Shen
D
D
Institute of Acupuncture and Channel, Anhui College of TCM, Hefei.
Liu
B
B
Wi
D
D
Zhang
F
F
Chen
Y
Y
D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D015671:Electroacupuncture; D005260:Female; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000517:prevention & control*; D013312:Stress, Physiological / Q000503:physiopathology*
D015306:Biogenic Monoamines