P-glycoprotein. To flip or not to flip?
The phenotype of mice homozygous for mutations of the mdr2 gene suggests that the mdr2 protein, which is closely related to the multidrug resistance P-glycoprotein, has a role in phospholipid transport.
Higgins
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CF
Imperial Cancer Research Fund Laboratories, Institute of Molecular Medicine, Oxford, UK.
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D018432:Drug Resistance, Multiple; D006720:Homozygote; D051379:Mice; D008817:Mice, Mutant Strains; D008954:Models, Biological; D009154:Mutation; D010641:Phenotype; D010743:Phospholipids / Q000378:metabolism
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D010743:Phospholipids