Benzophenone- and indolecarboxylic acids: potent type-2 specific inhibitors of human steroid 5 alpha-reductase.
Department of Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406.
D A
DA
Holt
D S
DS
Yamashita
A L
AL
Konialian-Beck
J I
JI
Luengo
A D
AD
Abell
D J
DJ
Bergsma
M
M
Brandt
M A
MA
Levy
D001577:Benzophenones / Q000138:chemical synthesis* / Q000494:pharmacology*; D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000494:pharmacology*; D042944:Cholestenone 5 alpha-Reductase; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
D001577:Benzophenones; D002264:Carboxylic Acids; D007211:Indoles; D010088:Oxidoreductases; D042944:Cholestenone 5 alpha-Reductase