[Evaluation on efficacy of plasma-derived hepatitis B vaccine and persistence of protective level after vaccination].
From October 1990 to May 1993, 300 students aged 18 to 20 years in Xian were studied to evaluate the efficacy of plasma-derived hepatitis B vaccine made in five factories. AntiHBs titer in 5 vaccinated groups reach the highest at the twelfth month after the first injection and decreased afterwards. The positive rate of anti-HBs decreased slowly, but the titer of anti-HBs fell sharply. Compared with the control group, the differences were all significant. The results showed that the efficacies of hepatitis B vaccine made in five factories were similar. The protection rate of hepatitis B vaccine against HBV infection was 79.22%.
Institute of Military Medicine, Guangzhou Command, PLA.
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Wang
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Wu
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Y
Li
D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood*; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D008297:Male; D014611:Vaccination
D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines