Antibacterial and antifungal sulfated alkane and alkenes from the hepatopancreas of the ascidian Halocynthia roretzi.
Four new antibacterial and antifungal sulfates, 2,6-dimethylheptyl sulfate [1], (4Z,7Z)-4,7-decadienyl sulfate [2], (4Z,7E)-4,7-decadienyl sulfate [3], and (3Z,6Z)-3,6,9-decatrienyl sulfate [4], have been isolated from the hepatopancreas of the ascidian Halocynthia roretzi. The structures were determined by spectral analysis.
Fusetani Biofouling Project, Exploratory Research for Advanced Technology (ERATO), Research Development Corporation of Japan (JRDC), Yokohama.
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S
Tsukamoto
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H
Kato
H
H
Hirota
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N
Fusetani
D000473:Alkanes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000475:Alkenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004064:Digestive System / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009090:Mucorales / Q000187:drug effects; D013329:Structure-Activity Relationship; D013464:Sulfuric Acids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D014561:Urochordata; D014733:Vibrio / Q000187:drug effects
D000473:Alkanes; D000475:Alkenes; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D013464:Sulfuric Acids