[Experimental and clinical bases for the use of antioxidants as agents for treating and preventing periodontitis].
The contribution of free-radical lipid and biopolymer oxidation to the pathogenesis of periodontitis is analyzed as reflected in published Russian and foreign literature. Enhanced autooxidation in periodontal tissue is shown to represent one of the mechanisms of the disease genesis, this prompting the use of antioxidants in the treatment an prophylaxis of periodontitis. Antioxidant effects on the course of the disease have been demonstrated experimentally and clinically. Criteria of antioxidants use as a means of treatment and prevention of periodontitis are offered.
Bobyrev
V N
VN
Rozkolupa
N V
NV
Skripnikova
T P
TP
D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D002908:Chronic Disease; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D010518:Periodontitis / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control; D010519:Periodontium / Q000187:drug effects / Q000378:metabolism
D000975:Antioxidants; D005609:Free Radicals
Eksperimental'nye i klinicheskie osnovy primeneniia antioksidantov kak sredstv lecheniia i profilaktiki parodontita.