The clonal nature of mediastinal germ cell tumors and acute myelogenous leukemia. A case report and review of the literature.
The clonal identity of a mediastinal germ cell malignant tumor and acute myelogenous leukemia is described in an 11-year-old boy in whom both tumors presented simultaneously. The relationship between these two histologically distinct malignancies is discussed in relation to this patient and 34 previously reported patients.
Woodruff
K
K
Gwynne Hazen Cherry Memorial Laboratories, UCLA School of Medicine 90024.
Wang
N
N
May
W
W
Adrone
E
E
Denny
C
C
Feig
S A
SA
D002648:Child; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008479:Mediastinal Neoplasms / Q000235:genetics*; D009373:Neoplasms, Germ Cell and Embryonal / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics*