Sequence analysis of the non-structural protein 2 from epizootic hemorrhagic disease viruses.
The non-structural protein 2 (NS2) of epizootic hemorrhagic disease virus serotype 1 (EHD-1) was cloned and sequenced. The NS2 gene was found to be 1185 bp containing a single open reading frame that encodes a 376 amino acid protein. A 97% nucleic acid identity was found between EHD-1 and a previously published NS2 sequence of EHD-2. Only a 60% nucleic acid identity was found between EHD and the bluetongue virus (BTV) serogroup. Comparison of the deduced amino acid sequences revealed 97% identity within the EHD serogroup, and less than or equal to 43% identity between serogroups.
USDA, Arthropod-borne Animal Diseases Research Laboratory, Laramie, WY 82071.
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D000595:Amino Acid Sequence; D001483:Base Sequence; D001820:Bluetongue virus / Q000235:genetics; D005814:Genes, Viral; D018164:Hemorrhagic Disease Virus, Epizootic / Q000145:classification / Q000235:genetics*; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D017361:Viral Nonstructural Proteins / Q000737:chemistry / Q000235:genetics*; D015678:Viral Structural Proteins / Q000235:genetics*
C091614:NS2 protein, epizootic hemorrhagic disease virus; D017361:Viral Nonstructural Proteins; D015678:Viral Structural Proteins