[The characteristics of eye regeneration in newts after complete retinal detachment induced by a change in the effect of gravitation in an experiment using a clinostat].
Morphological changes and proliferative activity of the neural retina cells after the neural retina detachment were studied in the newts subjected to microgravity in a clinostat. According to theoretical calculations, simulated microgravity could vary from 3.21 x 10(-2) to 8.05 x 10(-3) g. These conditions had a positive effect on morphological and functional restoration of the neural retina according to various criteria. Specifically, the increased number of Mullerian glial cells, increased relative volume of the plexiform layers, decreased mortality of the detached neural retina cells and increased redifferentiation of the retinal pigment epithelium and reattachment of the neural retina were observed. These changes were mainly found in the dorsal and central areas of the neural retina.
Grigorian
E N
EN
Anton
H J
HJ
D000818:Animals; D002452:Cell Count; D002455:Cell Division; D009336:Necrosis; D009799:Ocular Physiological Phenomena; D010999:Pleurodeles; D012038:Regeneration; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000473:pathology / Q000503:physiopathology*; D012399:Rotation / Q000009:adverse effects; D013997:Time Factors; D014893:Weightlessness / Q000009:adverse effects*
Osobennosti regeneratsii glaza tritonov posle polnoĭ otsloĭki setchatki, vyzvannye izmeneniem vliianiia gravitatsii v éksperimente s ispol'zovaniem klinostata.