Potent non-peptide fibrinogen receptor antagonists which present an alternative pharmacophore.
Ku
T W
TW
Research and Development Division, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406.
Miller
W H
WH
Bondinell
W E
WE
Erhard
K F
KF
Keenan
R M
RM
Nichols
A J
AJ
Peishoff
C E
CE
Samanen
J M
JM
Wong
A S
AS
Huffman
W F
WF
D000595:Amino Acid Sequence; D001569:Benzodiazepines / Q000138:chemical synthesis* / Q000494:pharmacology*; D001570:Benzodiazepinones / Q000138:chemical synthesis* / Q000494:pharmacology*; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000494:pharmacology; D010456:Peptides, Cyclic / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects; D010980:Platelet Membrane Glycoproteins / Q000037:antagonists & inhibitors*; D011487:Protein Conformation
C091721:7-((4-guanidinophenyl)aminocarbonyl)-3-oxo-4-phenethyl-1,4-benzodiazepine-2-acetic acid; D001570:Benzodiazepinones; D009842:Oligopeptides; D010456:Peptides, Cyclic; D010980:Platelet Membrane Glycoproteins; D001569:Benzodiazepines; C047981:arginyl-glycyl-aspartic acid