[Infections associated with intra- and extravascular catheters: factors involved in microorganism-biomaterial interactions].
Infections is one of the most common cause of catheter failure as well as the most difficult to manage, most often requiring catheter removal. Staphylococcus is the etiologic agent of such infections more frequently isolated, particularly Staphylococcus epidermidis. Several factors have been suggested to be involved in bacteria-biomaterial interactions such as catheter surface morphology, molecular biofilm and bacterial virulence features. Different strategies have been tried to avoid the development to catheter-associated infections: among them adsorption of antibiotic molecules to the catheter surface might represent a successful tool to improve catheter implant life.
Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Roma.
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Baldassarri
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Gelosia
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Donelli
D001422:Bacterial Adhesion; D001672:Biocompatible Materials; D002408:Catheters, Indwelling / Q000009:adverse effects*; D004866:Equipment Contamination; D005547:Foreign Bodies / Q000382:microbiology; D006801:Humans; D017053:Infection Control; D007239:Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology*; D012307:Risk Factors
D001672:Biocompatible Materials
Le infezioni associate a cateteri intra- ed extravascolari: fattori implicati nell'interazione microorganismo-biomateriale.