Insulin receptor disorders in Japan.
The clinical features of insulin receptor disorders found in Japan are summarized. About 20 cases of primary receptor mutations (type A syndrome of insulin resistance, leprechaunism and Rabson-Mendenhall syndrome) and 16 cases of autoantibodies against insulin receptor (type B syndrome of insulin resistance) are described in Japan. There was a trial of IGF-1 for some of the patients, revealing its usefulness.
Second Department of Internal Medicine, Kobe University School of Medicine, Japan.
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Kasuga
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Kadowaki
D000052:Acanthosis Nigricans / Q000453:epidemiology* / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D007333:Insulin Resistance / Q000235:genetics*; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011972:Receptor, Insulin / Q000235:genetics* / Q000276:immunology; D013577:Syndrome
D011972:Receptor, Insulin