Adverse reactions to therapy for HIV infection.
Although chronic drug therapy with antiretroviral agents and chemoprophylaxis has led to longer survival without disease, high rates of adverse reactions to agents used to treat HIV infection have been reported. The incidence of adverse drug reactions in patients with HIV infection varies with the type of drug therapy, dosage, drug-to-drug interactions, and the stage of HIV infection. This article discusses recognition, treatment, and prevention of adverse reactions to specific drugs and classifications of drugs.
Johns Hopkins University School of Medicine, Baltimore, Maryland.
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Barditch-Crovo
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Chaisson
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000517:prevention & control; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000009:adverse effects; D000981:Antiprotozoal Agents / Q000009:adverse effects; D000998:Antiviral Agents / Q000009:adverse effects* / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D004342:Drug Hypersensitivity / Q000209:etiology; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D015270:Mycobacterium avium-intracellulare Infection / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000981:Antiprotozoal Agents; D000998:Antiviral Agents