[The inhalational toxicity of the antibiotic preparation Bactericin for plant protection].
The acute and subacute inhalation toxicity of a new Bulgarian antibiotic preparation "Bactericin" for plant protection is examined. It is meant for the treatment of seeds from tomatoes before sowing. The inhalational toxicity is evaluated by a complex of toxicometric, integral, behavioural, clinic-laboratory, biochemical and histological methods. The maximum concentration reached by dispersing is 40 mg.m-3. In the condition of acute (unrepeated exposure) and subacute (60 exposure) the concentration of 40 mg.m-3 causes no lethality, symptoms of intoxication and toxic effects in the organism of white rats therefore it could be accepted as not operative. The preparation conceals no danger of acute and chronic inhalational poisonings when working with the latter. On the basis of the performed investigations and bearing in mind, that the preparation is in the group of the antibiotics, a proposal is made for the purpose of orientation MAG in the air of the working zone -0.5 mg.m-3.
Zh
Zh
Khalkova
Kh
Kh
Zaĭtsov
D000280:Administration, Inhalation; D000336:Aerosols; D000818:Animals; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents / Q000506:poisoning / Q000633:toxicity*; D001522:Behavior, Animal / Q000187:drug effects; D005260:Female; D005659:Fungicides, Industrial / Q000506:poisoning / Q000633:toxicity*; D007928:Lethal Dose 50; D018942:Macrolides; D008297:Male; D008452:Maximum Allowable Concentration; D011041:Poisoning / Q000097:blood / Q000473:pathology; D011090:Polyenes / Q000506:poisoning / Q000633:toxicity*; D051381:Rats; D013997:Time Factors
D000336:Aerosols; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D005659:Fungicides, Industrial; D018942:Macrolides; D011090:Polyenes; C089592:bactericin
Inkhalatorna toksichnost na antibiotichen preparat "Bakteritsin" za rastitelna zashtita.