Clinical aspects of contact allergy to corticosteroids.
Because of their anti-inflammatory activity, corticosteroids generally mask the clinical signs of a contact dermatitis to a corticosteroid preparation. The lesions usually present as chronic dermatitis, and the patients mostly report not exacerbations but failures to respond to corticosteroid therapy. Moreover, masking also occurs with patch-test reactions obtained with corticosteroid preparations and the corticosteroid molecules themselves. These are important reasons why contact allergy to such preparations has frequently been missed in the past.
Department of Dermatology, K.U. Leuven, Universitair Ziekenhuis, Belgium.
A
A
Dooms-Goossens
H
H
Degreef
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D006801:Humans
D000305:Adrenal Cortex Hormones