Localization of the human gene for fibulin-1 (FBLN1) to chromosome band 22q13.3.
Using fibulin-1 cDNA probes, we performed fluorescence in situ hybridization to map the human chromosomal location of the gene encoding the extracellular matrix and blood glycoprotein, fibulin-1 (FBLN1). The gene for fibulin-1 was mapped to a single site on the long arm of human chromosome 22 (22q13.3). The assignment of the chromosomal map position for the fibulin-1 gene will aid in the evaluation of its potential roles in human connective tissue and blood diseases.
Korenberg
J R
JR
Medical Genetics-Birth Defects Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Chen
X N
XN
Tran
H
H
Argraves
W S
WS
D002135:Calcium-Binding Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D002892:Chromosomes, Human, Pair 22; D006801:Humans; D017404:In Situ Hybridization, Fluorescence
D002135:Calcium-Binding Proteins; C060820:fibulin