Establishment of cell type specific gene transcription during sporulation in Bacillus subtilis.
Asymmetric cell division during the process of sporulation in the bacterium Bacillus subtilis generates dissimilar progeny that exhibit distinct programs of gene transcription. Recent work reveals a partner switching mechanism that governs the activity of the sporulation regulatory protein sigma F and that may be responsible for the establishment of cell type specific gene transcription.
Duncan
L
L
Biological Laboratories, Harvard University, Cambridge, Massachusetts 02138.
Alper
S
S
Losick
R
R
D000227:Adenine Nucleotides / Q000378:metabolism; D001412:Bacillus subtilis / Q000166:cytology / Q000235:genetics* / Q000502:physiology*; D002455:Cell Division; D005798:Genes, Bacterial; D005812:Genes, Switch; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D012808:Sigma Factor / Q000235:genetics; D013171:Spores, Bacterial / Q000235:genetics; D014158:Transcription, Genetic
D000227:Adenine Nucleotides; D012808:Sigma Factor; D017346:Protein Serine-Threonine Kinases