SPECT in adult mosaic Down's syndrome with early dementia.
A 52-year-old patient with mosaic Down's syndrome exhibiting clinical features of early dementia who underwent high resolution SPECT neuroimaging is reported. While a CT scan of the brain showed no abnormality, cranial SPECT confirmed the presence of marked cortical blood flow deficits.
Puri
B K
BK
Department of Psychiatry, Charing Cross and Westminister Medical School, London, England.
Zhang
Z
Z
Singh
I
I
D000544:Alzheimer Disease / Q000150:complications / Q000000981:diagnostic imaging*; D001921:Brain / Q000000981:diagnostic imaging*; D004314:Down Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009030:Mosaicism; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime