Effects of bone mineral density on pedicle screw fixation.
METHODS
In an attempt to evaluate the effects of bone mineral density on the quality of fixation of pedicle screws in the lumbar spine, the axial pullout force was determined and compared in normal and osteoporotic human lumbar spines.


OBJECTIVE
Four techniques of screw hole preparation were evaluated. Two pedicle screw/offset laminar hook constructs also were evaluated to determine whether the adjunct fixation of the laminar hooks would improve quality of fixation to a level sufficient to allow their use in the osteoporotic lumbar spine.


METHODS
Pedicle screws were inserted by one of the listed techniques into fresh frozen cadaveric human spines. The fixation strength then was evaluated by pullout on a uniaxial testing frame.


RESULTS
Bone mineral density was a strong influence on axial pullout force. In normal bone, the method of screw hole preparation did not significantly affect the quality of fixation. However, in the osteoporotic spine, either an untapped screw hole or the tapping of a screw hole with a 5.5 mm tap improved the pullout force a statistically significant amount (P < 0.003). Also, a pedicle screw with offset hooks at two adjacent levels improved the fixation significantly, increasing the pullout force to twice the expected value.


CONCLUSIONS
Pedicle screw pullout strength was highly correlated with bone mineral density. A 5.5 mm tap or preparation with a ganglion knife improved pullout strength. Use of pedicle screws in conjunction with laminar hooks at two levels improved pullout strength.
Department of Orthopaedics, Tulane University School of Medicine, New Orleans, Louisiana.
T L
TL
Halvorson
L A
LA
Kelley
K A
KA
Thomas
T S
TS
Whitecloud
S D
SD
Cook
D001696:Biomechanical Phenomena; D015519:Bone Density; D001863:Bone Screws / Q000592:standards; D005069:Evaluation Studies as Topic; D006801:Humans; D016268:Internal Fixators / Q000592:standards; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000601:surgery; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography