The frontal lobes and traumatic brain injury.
The authors review 1) the pathophysiological, neuroimaging, and neurobehavioral evidence for frontal lobe involvement in closed head injury; 2) studies elucidating the cognitive deficits and behavioral disturbance related to frontal lobe lesions associated with head injury; and 3) pharmacologic treatment of the neuropsychiatric manifestations of frontal lobe injury, including emerging therapies.
Levin
H
H
Division of Neurosurgery, University of Maryland Medical System, Baltimore.
Kraus
M F
MF
D000328:Adult; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology / Q000534:rehabilitation; D002648:Child; D003952:Diagnostic Imaging; D005625:Frontal Lobe / Q000293:injuries* / Q000503:physiopathology; D016489:Head Injuries, Closed / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology / Q000534:rehabilitation; D006801:Humans; D011939:Mental Recall / Q000502:physiology; D009042:Motivation; D009483:Neuropsychological Tests; D011340:Problem Solving / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology; D012050:Rehabilitation, Vocational / Q000523:psychology