Treatment of perioperative low cardiac output syndrome.
New approaches to the treatment of perioperative low cardiac output are considered. In particular, use of the phosphodiesterase III inhibitors and their cardiovascular actions are reviewed and contrasted with those of conventional inotropic agents. The increasing recognition of right-sided dysfunction is highlighted, and appropriate therapeutic strategies are considered. The increasing role of pulmonary-specific vasodilators such as inhaled nitric oxide is emphasized. Strategies to preserve right heart perfusion while producing pulmonary vasodilatation are discussed.
Doyle
A R
AR
Department of Anaesthesia, Papworth Hospital, Cambridgeshire, England.
Dhir
A K
AK
Moors
A H
AH
Latimer
R D
RD
D002303:Cardiac Output, Low / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D002316:Cardiotonic Agents / Q000145:classification / Q000627:therapeutic use*; D006801:Humans; D018497:Ventricular Dysfunction, Right / Q000628:therapy; D016278:Ventricular Function, Right / Q000502:physiology
D002316:Cardiotonic Agents