[The treatment of atopic rhinitis in children with an accelerated variant of specific immunotherapy].
An intensified course of specific immunotherapy (36 days) has been tried in 72 children with atopic vasomotor rhinitis. The age of the patients ranged from 5 to 15 years. The effectiveness of the treatment was assessed by nasal mucosa function, cellular and humoral immunity measured throughout the treatment and 6 moths after it. Good results were obtained in 71.1% of the patients, satisfactory in 24.4%, unresponsive children made up 4.2%. No complications occurred. During the treatment adverse reactions were noted in 11 children. Short-term discontinuation of the allergen administration corrected the situation. Clinical, functional and immunological findings permitted the authors to conclude on the expediency of a short-term specific immunotherapy in atopic rhinitis management in children.
Gamzatova
A A
AA
Gadzhimirzaev
G A
GA
D000293:Adolescent; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D003888:Desensitization, Immunologic / Q000379:methods*; D005069:Evaluation Studies as Topic; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D007111:Immunity, Cellular; D009297:Nasal Mucosa / Q000503:physiopathology; D012223:Rhinitis, Vasomotor / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors
Lechenie atopicheskogo rinita u deteĭ uskorennym variantom spetsificheskoĭ immunoterapii.