[In vivo observations and electron microscopy in the treatment of experimental HSV keratitis with monoclonal antibodies].
In vivo observations and electron microscopy showed that topical use of anti-HSV monoclonal glycoprotein antibodies produced marked antiviral effects in inhibiting the development of experimental herpetic keratitis in rabbits and in protecting the susceptible corneal cells. As a new biological product, the anti-HSV monoclonal antibodies may provide a new approach to the treatment of HSV keratitis.
Yu
J
J
Department of Ophthalmology, Tang Du Hospital, Fourth Military Medical University, Xi-an.
Zhang
Y H
YH
Zhang
D G
DG
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003315:Cornea / Q000648:ultrastructure*; D018259:Herpesvirus 1, Human / Q000276:immunology*; D016849:Keratitis, Herpetic / Q000473:pathology* / Q000628:therapy; D009883:Ophthalmic Solutions; D011817:Rabbits
D000911:Antibodies, Monoclonal; D009883:Ophthalmic Solutions