Mixed connective tissue disease: recurrent episodes of optic neuropathy and transverse myelopathy. Successful treatment with plasmapheresis.
Severe neuropsychiatric manifestations in mixed connective tissue disease (MCTD) are thought to be quite rare. We report an unusual case of MCTD with recurrent optic neuropathy and transverse myelopathy suggestive of a relapsing-remitting demyelinating disorder. Symptoms responded dramatically to a treatment with plasmapheresis and immunosuppressive medication.
Universitätsklinikum Rudolf Virchow, Freie Universität Berlin, Germany.
K M
KM
Flechtner
K
K
Baum
D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008947:Mixed Connective Tissue Disease / Q000150:complications* / Q000628:therapy*; D009188:Myelitis, Transverse / Q000175:diagnosis / Q000209:etiology*; D009901:Optic Nerve Diseases / Q000209:etiology*; D010956:Plasmapheresis; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence
D011239:Prednisolone; D001379:Azathioprine