Neurotoxic effects of selected metals.
A chemical is considered to be neurotoxic if it is capable of inducing a consistent pattern of neural dysfunction or lesion in the nervous system. Several metals are known as neurotoxic. Among them, four have been selected as being especially important from the occupational point of view, lead, manganese, aluminium, and mercury. All four have proved to be neurotoxic even though the toxic mechanisms may be unclear or unknown. This paper reviews the recently published documentation on the neurotoxic properties of these metals, from the general as well the occupational point of view.
Department of Neuromedicine, National Institute of Occupational Health, Solna, Sweden.
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Wennberg
D000328:Adult; D000535:Aluminum / Q000009:adverse effects; D002648:Child; D006801:Humans; D007855:Lead Poisoning / Q000175:diagnosis; D008345:Manganese / Q000009:adverse effects; D008630:Mercury Poisoning / Q000175:diagnosis; D008670:Metals / Q000009:adverse effects*; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis; D009460:Neurologic Examination / Q000187:drug effects; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis; D016273:Occupational Exposure / Q000009:adverse effects*
D008670:Metals; D008345:Manganese; D000535:Aluminum