Isolation of serotonin from the accessory salivary glands of the marine snail Nucella lapillus.
We report here the presence of a bioactive compound in the secretion of the accessory salivary glands (ASGs) of Nucella lapillus. We have purified the compound using HPLC and identified it as serotonin by mass spectrometry, UV spectroscopy, HPLC and capillary electrophoresis. Serotonin was not found in the secretions of the acinous salivary glands or the hypobranchial gland. The amount of serotonin in the secretion of the ASGs does not show seasonal or regional variation.
Department of Biology, Royal Holloway, University of London, Egham, Surrey, U.K.
D J
DJ
West
E B
EB
Andrews
A R
AR
McVean
D J
DJ
Osborne
M C
MC
Thorndyke
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004586:Electrophoresis; D013058:Mass Spectrometry; D008978:Mollusk Venoms / Q000737:chemistry*; D009132:Muscles / Q000187:drug effects; D012469:Salivary Glands / Q000378:metabolism; D012701:Serotonin / Q000302:isolation & purification* / Q000494:pharmacology; D012908:Snails / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet
D008978:Mollusk Venoms; D012701:Serotonin