[Experimental study of radiated pig skin incorporated with norfloxacin and silver].
This paper presents the preparation and experimental use of radiated pigskin incorporated with norfloxacin and silver (RPSNS). The results show that tensile strength, tissue adherence and water-vaporu permeability of RPSNS are not significantly different from that of pigskin without radiation. The histological structure of RPSNS is essentially normal. However, some of the epidermal cells present vesicles. No positive culture is found in RPSNS and radiated pigskin, while the rate of positive bacterial culture of pigskin sterilized by Bromogeramin is 10%. RPSNS can effectively inhibit Staphy. aureus, Ps aeruginosa, E. coli, Proteus and Klebsiella. The results indicate that RPSNS is a kind of sterile biological dressing with strong anti-bacterial effect.
Burn Institute, First Affiliated Hospital, Jiangxi Medical College, Nangchang.
G
G
Li
Y
Y
Cao
X
X
Wu
D000818:Animals; D001684:Biological Dressings; D009643:Norfloxacin; D011817:Rabbits; D012835:Silver Nitrate; D012867:Skin / Q000528:radiation effects*; D013552:Swine
D012835:Silver Nitrate; D009643:Norfloxacin