Differential reactivities of antibodies to HIV and HTLV-I in sera of suspected AIDS and ARC patients.
Sera collection from 255 clinically diagnosed AIDS and ARC patients were analyzed for antibodies to HIV and HTLV-I by Western blot and particle agglutination methods respectively. Antibodies to HIV were detected in 37.3% of the sera collected as compared to 5.5% for HTLV-I. Most (95%) of the HIV positive sera had dual reactivity to both HIV-I and HIV-2. Antibodies to HTLV-1 were more frequently detected in HIV positive sera (11.58%) than in HIV negative sera (1.88%). Conversely, antibodies to HIV were detected twice as frequently in HTLV-1 positive sera (78.6%) than in HTLV-1 negative sera (34.85%).
Noguchi Memorial Institute for Medical Research, University of Ghana, Legon.
M
M
Aidoo
O
O
Nishiwaki
H
H
Akari
J A
JA
Brandful
W
W
Ampofo
M
M
Hayami
N K
NK
Ayisi
D000386:AIDS-Related Complex / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology*; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology*; D015153:Blotting, Western; D005869:Ghana / Q000453:epidemiology; D015483:HIV Antibodies / Q000097:blood*; D015528:HIV Seroprevalence; D015481:HTLV-I Antibodies / Q000097:blood*; D006801:Humans; D011159:Population Surveillance; D016036:Seroepidemiologic Studies
D015483:HIV Antibodies; D015481:HTLV-I Antibodies