[Congenital urethra valves; experiences in 73 children].
OBJECTIVE
To inventory symptoms of children with urethral valves, and their prognosis.


METHODS
Descriptive.


METHODS
Department of paediatrics and urology, University of Nijmegen.


METHODS
Symptoms were evaluated from clinical data and interviews of the parents of 73 patients. The glomerular filtration rate (GFR) was calculated from the serum creatinine level by the method of Counahan.


RESULTS
Symptoms indicating an urethral obstruction, e.g. diminished urinary jet, were rare (20% of the children). General symptoms prevailed: vomiting, anorexia, growth failure, fever. After 2 years 11 out of 53 children had a GFR < 25 ml/min/1.73 m2 body surface area.


CONCLUSIONS
Specific symptoms indicating an urethral obstruction are rare. The glomerular filtration is often diminished. There are no measures to prevent loss of renal function.
Afd. Kindergeneeskunde, Academisch Ziekenhuis, Nijmegen.
J
J
de Jongh-van Hoof
J D
JD
de Vries
L A
LA
Monnens
D002648:Child; D002675:Child, Preschool; D005919:Glomerular Filtration Rate; D006801:Humans; D006984:Hypertrophy; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014463:Ultrasonography; D014521:Urethra / Q000002:abnormalities* / Q000000981:diagnostic imaging; D001743:Urinary Bladder / Q000473:pathology; D014555:Urination Disorders / Q000175:diagnosis* / Q000209:etiology*; D014567:Urography
Aangeboren urethrakleppen; ervaringen bij 73 kinderen.