SPECT data in a case of secondary Capgras delusion.
Capgras' delusion (CD) may be secondary to a neurologic lesion, particularly in the right frontal or occipital regions. A 40-year-old woman with multiple sclerosis underwent SPECT during and after an episode of CD. Analysis during delusion showed an uptake defect in the right parietal cortex with an 11% index of asymmetry (normal: < or = 4%). Post-delusion SPECT showed decreased bifrontal and biparietal cortical uptake indices but a normal index of asymmetry. Functional brain imaging may provide clues to the psychopathology of CD.
Lebert
F
F
Memory Disorders, Unit, Hospitalier Régional, Universitaire, Lille, France.
Pasquier
F
F
Steinling
M
M
Cabaret
M
M
Caparros-Lefebvre
D
D
Petit
H
H
D000328:Adult; D001931:Brain Mapping; D002194:Capgras Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D002540:Cerebral Cortex / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002547:Cerebral Palsy / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D019965:Neurocognitive Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000000981:diagnostic imaging / Q000503:physiopathology; D015899:Tomography, Emission-Computed, Single-Photon