Histiocytic cytophagic panniculitis: a rare late complication of allogeneic bone marrow transplantation.
Histiocytic cytophagic panniculitis (HCP) is the name given to the hemophagocytic syndrome when subcutaneous fat is involved. Histologically, it is characterized by phagocytosis of blood elements by histiocytes that appear to be benign. We report this rare skin disease in a 46-year-old patient that occurred 32 months after an allogeneic bone marrow transplantation. This skin disease could be a manifestation of graft-versus-host disease, although the connection remains speculative.
Department of Medicine, Universidad de Salamanca, Spain.
J
J
Galende
M L
ML
Vazquez
J
J
Almeida
M C
MC
Peña Penabad
E
E
Fernandez Lopez
M D
MD
Caballero
J F
JF
San Miguel
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D015614:Histiocytosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015434:Panniculitis / Q000209:etiology* / Q000473:pathology; D014184:Transplantation, Homologous