Increased metal release from cemented femoral components made of titanium alloy. 19 hip prostheses followed with radiostereometry (RSA).
In 19 patients the concentrations of metal were measured in serum, urine and joint fluid 2 years after implantation of uncemented commercially pure titanium acetabular cups and cemented or uncemented femoral components made of titanium alloy. A ceramic against the polyethylene articulation was used. The fixation of the components was followed with radiostereometry (RSA). Samples from 12 patients scheduled for hip or knee prostheses and without any metallic implant were used as controls. High levels of titanium were found in cemented hips and when large acetabular cups had been inserted. Increased aluminum levels were also noted in the cemented hips. Vanadium was not detected in any of the samples. Micromotions were detected in most of the implants, but the magnitude of these movements could not be used to predict the release of metal into the synovial fluid.
Department of Orthopedics, Sahlgren Hospital, Göteborg, Sweden.
J
J
Kärrholm
W
W
Frech
K G
KG
Nilsson
F
F
Snorrason
D000328:Adult; D000368:Aged; D000535:Aluminum / Q000032:analysis*; D001843:Bone Cements / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D011475:Prosthesis Failure; D016059:Range of Motion, Articular; D013238:Stereotaxic Techniques; D013582:Synovial Fluid / Q000737:chemistry; D014025:Titanium / Q000032:analysis*; D014639:Vanadium / Q000032:analysis*
D001843:Bone Cements; D014639:Vanadium; D000535:Aluminum; D014025:Titanium