Aluminium in rat cerebellar primary cultures: glial cells and GABAergic neurones.
Experimental evidence of the preferential uptake of aluminium by GABAergic neurones and glial cells was provided by synchrotron spectromicroscopy studies. We observed rat cerebellar cultures enriched for GABAergic neurones or glial cells exposed to aluminium ions, detecting the presence and identifying the chemical status of aluminium on cell structures.
Istituto di Struttura della Materia del CNR, Frascati, Roma, Italy.
G
G
De Stasio
D
D
Mercanti
M T
MT
Ciotti
D
D
Dunham
T C
TC
Droubay
B P
BP
Tonner
P
P
Perfetti
G
G
Margaritondo
D015502:Absorptiometry, Photon; D000535:Aluminum / Q000378:metabolism*; D000818:Animals; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology / Q000378:metabolism* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009457:Neuroglia / Q000378:metabolism* / Q000648:ultrastructure; D009474:Neurons / Q000378:metabolism* / Q000648:ultrastructure; D017785:Photons; D051381:Rats; D017356:Synchrotrons; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D005680:gamma-Aminobutyric Acid; D000535:Aluminum