[Geographic aspects in the epidemiology of multiple sclerosis].
The Czech Republic is one of the countries with a high and heterogeneous prevalence of multiple sclerosis with the highest prevalence in the zone beneath the Ore Mountains (Krusné hory) and with a maximum in the territory of Teplice. The focus of the disease is consistent with the area with a generally higher health risk and polluted environment. The adverse exogenous component alters significantly immune mechanisms and participates in the provoking and trigger effect; however, its individual factors are difficult to identify as key or specific factors. It is assumed that global factors, long-term exposure and susceptibility of genetically predisposed subjects are involved.
Rehabilitacní lázenské sanatorium, Vráz u Písku.
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Lenský
D018153:Czech Republic / Q000453:epidemiology; D006801:Humans; D009103:Multiple Sclerosis / Q000453:epidemiology*; D012307:Risk Factors
Geografický aspekt v epidemiologii sclerosis multiplex.