[Using ELISA to evaluate the serologic and epidemiologic effect following rabies vaccination].
After vaccinating the people bitten by animals against rabies, we have examined their serum antibodies by using ELISA. One year later, we sent a mail to everyone of them inquiring if he had contracted rabies. The response rate was 85%. The case fatality rate of the positive antibody group was 0.24% (1/415). The case fatality rate of the negative antibody group was 3.16 (3/95). It showed that there was significant difference in the case fatality rate of rabies between the two groups, (P = 0.022). The dead person of the positive antibody group was bitten on his cheek by a rabid dog. He had not cleaned his wound. He had received 6 injections of rabies vaccines. His incubation period was 28 days. The P/N of serum antibody on the 28th day was 3.27.
Hebei Provincial Hygiene and Epidemic Prevention Station, Baoding.
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D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011818:Rabies / Q000453:epidemiology / Q000517:prevention & control*; D011819:Rabies Vaccines / Q000276:immunology*; D016036:Seroepidemiologic Studies; D014611:Vaccination
D000914:Antibodies, Viral; D011819:Rabies Vaccines