[The comparative action of cholinergic substances on the cervical and thoracic trachea of the rat].
Different reactions were found in the cervical and thoracal parts of the trachea to application of acetylcholine, cholinomimetics and cholinolytics. The effect of acetylcholine on the cervical part is associated with muscarinic receptors in muscles. In the thoracal trachea, the effect of acetylcholine at a low concentration is associated mainly with muscle cholinoreceptors, whereas at high concentrations its effect is determined by both myogenic and neurogenic factors. Cholinergic systems of the intramural ganglia are involved in contraction and relaxation of tracheal smooth muscle in rats.
I K
IK
Shopotov
A N
AN
Fedin
A I
AI
Krivchenko
O V
OV
Vasil'eva
D000818:Animals; D018678:Cholinergic Agents / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005724:Ganglia / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000294:innervation / Q000502:physiology; D051381:Rats; D014132:Trachea / Q000187:drug effects* / Q000294:innervation / Q000502:physiology
D018678:Cholinergic Agents
Sravnitel'noe deĭstvie kholinergicheskikh veshchestv na sheĭnuiu i grudnuiu chasti trakhei krysy.