[Treatment of osteoporosis by the gynecologist].
At least one of four women is suffering from osteoporosis with fractures of vertebrae, forearm or hip. Maintenance of bone-mass is a crucial argument for long-term estrogen replacement for prophylaxis of osteoporosis. 2 mg estradiol or 0.625 mg conjugated estrogens, or 50-100 micrograms estradiol percutaneously are equally sufficient for prevention of osteoporosis. The additional use of a progestagen in women with intact uterus may support the antiresorptive effects of estrogens. Improvement of patients' compliance of estrogen substitution--administered today in only 25% of postmenopausal women in Germany--by sufficient information upon estrogen replacement therapy provided by the medical community is an awarding task for physicians and scientists engaged in the field of menopause and prevention of osteoporosis.
Zentrum für Frauenheilkunde, Westfälischen Wilhelms-Universität Münster.
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Schneider
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Dören
D000279:Administration, Cutaneous; D000284:Administration, Oral; D000368:Aged; D015519:Bone Density / Q000187:drug effects; D004958:Estradiol / Q000008:administration & dosage / Q000009:adverse effects; D015914:Estrogen Replacement Therapy; D004966:Estrogens, Conjugated (USP) / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D005858:Germany; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy* / Q000209:etiology; D011374:Progesterone / Q000008:administration & dosage / Q000009:adverse effects
D004966:Estrogens, Conjugated (USP); D011374:Progesterone; D004958:Estradiol
Die Behandlung der Osteoporose in der Hand des Gynäkologen.