Transient protein S deficiency associated with cerebral venous thrombosis in active ulcerative colitis.
Cerebral venous thrombosis is an uncommon complication of ulcerative colitis. We report the case of a 29-yr-old female with a recent diagnosis of ulcerative colitis who suffered stroke secondary to thrombosis of the veins of Galen and straight sinus. A search for a hypercoagulable state revealed a nonfamilial transient protein S deficiency. Possible involvement of C4b-binding protein in this hypercoagulable state is discussed.
Division of Gastroenterology, University of Alabama at Birmingham.
M F
MF
Vaezi
P K
PK
Rustagi
C O
CO
Elson
D000208:Acute Disease; D000328:Adult; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology*; D018455:Protein S Deficiency / Q000150:complications*