Functioning ectopic supradiaphragmatic pituitary adenomas.
Pituitary adenomas arising far from the pituitary gland occur rarely as a result of defects in embryological migration. Likewise, there have been reports of isolated suprasellar adenomas (clinically nonfunctioning), presumably derived from cells of the pars tuberalis. In this report, we present four cases of functional pituitary adenomas (three adrenocorticotrophic hormone, one prolactin) confined to the supradiaphragmatic region. In each case, the tumors were initially treated unsuccessfully by operations via the transsphenoidal route because of expected intrasellar processes with suprasellar extension.
Department of Neurosurgery, Cochin Hospital, Paris, France.
E H
EH
Dyer
T
T
Civit
J P
JP
Abecassis
P J
PJ
Derome
D000236:Adenoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D002828:Choristoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D010902:Pituitary Gland; D010910:Pituitary Irradiation; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D012086:Reoperation; D014057:Tomography, X-Ray Computed