Vertical transmission of HIV infection.
Transmission of HIV infection from mother to child may occur before, during or after delivery. Estimates of the rate of vertical transmission range from 15-20% in Europe to 25-35% in Africa. Mother-to-child transmission is associated with progression of disease in the mother, severe prematurity and breastfeeding. The association with mode of delivery needs further investigation. Attention is now being given to intervention to reduce mother-to-child transmission of HIV infection.
Department of Paediatric Epidemiology, Institute of Child Health, London, UK.
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Newell
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Peckham
D000349:Africa / Q000453:epidemiology; D001942:Breast Feeding; D002648:Child; D036861:Delivery, Obstetric; D005060:Europe / Q000453:epidemiology; D005260:Female; D005315:Fetal Diseases / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D005500:Follow-Up Studies; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control / Q000635:transmission*; D006801:Humans; D007112:Immunity, Maternally-Acquired; D015994:Incidence; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D018445:Infectious Disease Transmission, Vertical; D009035:Mothers; D011247:Pregnancy; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors
D015483:HIV Antibodies