[C14-aminopyrine breath test and enzymatic liver tests in workers employed by the coke tar distillation department].
A group of 400 subjects divided into three sub-groups was examined. Group I consisted of 130 persons employed at the coke tar distillation department. Group II (controls) consisted of 70 persons also employed at the coke plant but free from occupational exposure. Group III was composed of 200 workers employed at the Building Factory. C14-aminopyrine breath test (ABT) was performed in 30 subjects randomly assigned from each group. A standard enzymatic liver test was assessed in all subjects examined. The range of tests performed did not permit to indicate the toxic effect of occupational environment on the liver tissue. Abnormal enzymatic liver test found in all groups could results, among others, from alcohol abuse among those tested. However, it was revealed that aromatic hydrocarbons to which workers of the coke tar distillation department were exposed to, stimulated the activity of the liver microsomal oxygenase assessed by ABT.
Katedry i Kliniki Chorób Wewnetrznych i Zawodowych w Zabrzu.
W
W
Pokrzywnicki
J
J
Sroczyński
H
H
Rudzki
W
W
Grzeszczak
D000328:Adult; D000632:Aminopyrine / Q000032:analysis*; D001944:Breath Tests; D002617:Chemical Industry; D003077:Coke / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure
D003077:Coke; D000632:Aminopyrine
Test oddechowy z C14-aminopiryna i klasyczne enzymatyczne testy watrobowe u pracowników zatrudnionych w wydziale weglopochodnych zakładów koksochemicznych.