Case report of interferon alfa therapy for multiple myeloma during pregnancy.
Interferon alfa is broadly accepted as treatment for multiple myeloma, but its potential teratogenicity and mutagenicity during pregnancy in the human are still in dispute. We report a case of successful delivery after interferon alfa therapy for multiple myeloma during the first trimester of pregnancy. We reviewed the cases of interferon alfa treatment given during pregnancy for a malignancy and discovered that all of them have had successful deliveries and normal healthy babies. Additional studies should be encouraged to confirm the safety of interferon alfa therapy during pregnancy.
Department of Obstetrics and Gynecology, University of California, Irvine, Orange 92613-1491.
H
H
Sakata
J
J
Karamitsos
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B
Kundaria
P J
PJ
DiSaia
D000328:Adult; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D009101:Multiple Myeloma / Q000188:drug therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*; D011261:Pregnancy Trimester, First
D016898:Interferon-alpha