Spinal cord stimulation for the treatment of progressive systemic sclerosis and Raynaud's syndrome.
Progressive Systemic Scleroderma (PSS) is a generalized disease of connective tissue involving the skin, as well as other internal organs. The cutaneous signs are characterized by a progressive sclerosis and loss of function or dexterity in the hands. Between 1987 and 1992, 15 patients affected by scleroderma were treated by means of spinal cord stimulation (SCS) in order to reduce signs and symptoms related to vascular damage. The follow-up ranged from 12 months to 6 years. The study confirms that SCS is an effective therapy in patients with PSS and Raynaud's phenomenon because of its beneficial effects on the Raynaud episodes, ulcers, pain, vascular sclerosis and hand function. This method may have a primary role in the treatment of this chronic disorder because of the high probability of failure of other medical or surgical therapy.
Department of Neurosurgery, University of Genoa Medical School, Italy.
N
N
Francaviglia
C
C
Silvestro
M
M
Maiello
R
R
Bragazzi
C
C
Bernucci
D000328:Adult; D004599:Electric Stimulation Therapy; D005121:Extremities / Q000098:blood supply; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011928:Raynaud Disease / Q000601:surgery / Q000628:therapy*; D012595:Scleroderma, Systemic / Q000601:surgery / Q000628:therapy*; D013116:Spinal Cord / Q000601:surgery; D014664:Vasodilation