In vitro activity of eight antibiotics against Salmonella and Shigella species.
The minimum inhibitory concentrations (MICs) of ampicillin, chloramphenicol, trimetoprimsulfamethoxazole (TMP-SMX), ofloxacin, ciprofloxacin, pefloxacin, enoxacin and fleroxacin for Salmonella spp. (n = 72) and Shigella spp. (n = 52) were established. S. typhi isolates were all susceptible to all of the antibiotics tested. In non-typhi salmonellae and Shigella spp., resistance to ampicillin, chloramphenicol and TMP-SMX with various rates were encountered, but all isolates were susceptible to fluoroquinolones.
Laboratory of Clinical Bacteriology, Ibn-iSina Hospital of Ankara University, Turkey.
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Arman
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Willke
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Tural
D000667:Ampicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002701:Chloramphenicol / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D015365:Enoxacin / Q000494:pharmacology; D016576:Fleroxacin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015242:Ofloxacin / Q000494:pharmacology; D015366:Pefloxacin / Q000494:pharmacology; D012475:Salmonella / Q000145:classification / Q000187:drug effects*; D012760:Shigella / Q000145:classification / Q000187:drug effects*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D015366:Pefloxacin; D015365:Enoxacin; D002939:Ciprofloxacin; D002701:Chloramphenicol; D000667:Ampicillin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D015242:Ofloxacin; D016576:Fleroxacin