Brainstem auditory evoked response development in preterm and term baboons (Papio hamadryas).
Brainstem auditory evoked responses were recorded longitudinally from 11 neonatal baboons (Papio hamadryas), 6 of which were preterm. Recordings were made in unsedated animals from day 161 to day 362 after conception (term = 182 days). The pattern of development of both waveform morphology and of wave latency was consistent with that seen in the human neonate, with a rapid maturation of the response during the perinatal period, and then a slower development to adult values. Brainstem conduction time was measured from the wave I to wave IV interval, and this demonstrated a similar pattern, with a rapid decrease in latency up to term, and then decreasing more slowly to reach adult values by 4 months of age in the baboon.
Department of Perinatal Medicine, King George V Hospital, Camperdown, NSW, Australia.
D A
DA
Edwards
D J
DJ
Henderson-Smart
A G
AG
Pettigrew
A
A
Wetzlar
A F
AF
Phippard
D000375:Aging / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn; D001933:Brain Stem / Q000196:embryology / Q000254:growth & development / Q000502:physiology*; D002585:Cesarean Section; D036861:Delivery, Obstetric; D005314:Embryonic and Fetal Development; D005072:Evoked Potentials, Auditory; D005260:Female; D005865:Gestational Age; D008297:Male; D008598:Menstruation; D010215:Papio; D011247:Pregnancy; D011323:Primates; D013045:Species Specificity