On the interspike intervals calculated from diffusion approximations of Stein's neuronal model with reversal potentials.
In this paper we compare a discontinuous model with two diffusion models of a simulated neuron. The mean and coefficient of variation of the interspike intervals were calculated for these three models. The means were found to be shorter for the diffusion approximations than for the discontinuous model for all values of parameters. By increasing the excitation, the difference between firing frequencies generated by the models became smaller. The coefficient of variation (CV) exhibited a relatively close agreement for all three models. The firing patterns for both diffusion models were similar to each other.
Institute of Biophysics, 3rd Medical School of Charles University, Prague, Czech Republic.
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Musila
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Lánský
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D008433:Mathematics; D008564:Membrane Potentials / Q000502:physiology; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*