Distribution of immediate early gene zif-268, c-fos, c-jun and jun-D mRNAs in the adult cat with special references to brain region related to vision.
The distribution of immediate early gene zif-268, c-fos, c-jun and jun-D mRNAs was investigated in the visual cortex, dorsal lateral geniculate nucleus and hippocampus of the adult cat brain with in situ hybridization. In area 17, zif-268, c-jun and jun-D were found predominantly in layers II-III and VI, while c-fos mRNA was abundant in layer VI. In area 18, the zif-268, c-fos and c-jun labelling pattern was identical to that of area 17, this was not true for jun-D. In area 19, only c-jun retained the lamination pattern of areas 17 and 18, while zif-268, c-fos and jun-D were homogeneously distributed. In the dorsal lateral geniculate nucleus, only c-fos and jun-D resulted in labelling. In the pyramidal layer of hippocampus, zif-268 was found in CA1-4, c-jun in CA1-3, and jun-D in CA2-4. In the dentate gyrus, c-jun was abundant, jun-D moderate and zif-268 faint. C-fos labelling was absent in the hippocampal formation.
Brain Research Unit, Université Libre de Bruxelles, Belgium.
F
F
Zhang
P
P
Halleux
L
L
Arckens
W
W
Vanduffel
L
L
Van Brée
P
P
Mailleux
F
F
Vandesande
G A
GA
Orban
J J
JJ
Vanderhaeghen
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002415:Cats; D004268:DNA-Binding Proteins / Q000235:genetics; D017781:Genes, Immediate-Early / Q000235:genetics*; D016762:Genes, fos; D016758:Genes, jun; D005829:Geniculate Bodies / Q000033:anatomy & histology / Q000378:metabolism; D006624:Hippocampus / Q000033:anatomy & histology / Q000378:metabolism; D017403:In Situ Hybridization; D015345:Oligonucleotide Probes; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics; D014785:Vision, Ocular / Q000502:physiology*; D014793:Visual Cortex / Q000033:anatomy & histology / Q000378:metabolism
D004268:DNA-Binding Proteins; D015345:Oligonucleotide Probes; D012333:RNA, Messenger; D014157:Transcription Factors