Application of fluorocarbon emulsions as components of cosmetics and medical ointments.
Localization and accumulation of perfluorochemicals (PFCs) in the skin and internal organs of rats after prolonged surface application of the concentrated PFC emulsion, fluorogel, have been studied by electron microscopy and gas-chromatography. The PFC concentration in skin was about 0.03-0.04 mg per 1 g of tissue. Few aggregates of emulsion particles were detected in derma. The oxygen-dependent favorable effect of fluorogel treatment of thermic burned skin and wound surface was found.
Research Center, NIZAR Pharm.Co., Moscow, Russia.
O E
OE
Oxynoid
D P
DP
Sydliarov
Y D
YD
Aprosin
V V
VV
Obraztsov
D000818:Animals; D002056:Burns / Q000188:drug therapy / Q000503:physiopathology; D002849:Chromatography, Gas; D003358:Cosmetics / Q000737:chemistry*; D004655:Emulsions; D005466:Fluorocarbons / Q000493:pharmacokinetics*; D008297:Male; D008854:Microscopy, Electron; D009824:Ointments / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000378:metabolism*; D014018:Tissue Distribution; D014945:Wound Healing / Q000187:drug effects
D003358:Cosmetics; D004655:Emulsions; D005466:Fluorocarbons; D009824:Ointments