T-cell regulation. Tails of phosphorylation and T-cell activation.
How do quantitative differences in T-cell signal transduction lead to qualitatively different responses? Recent work demonstrates that even well-established regulatory paradigms are open to question.
Ucker
D S
DS
Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago 60612.
D000818:Animals; D006801:Humans; D017493:Leukocyte Common Antigens / Q000502:physiology; D008213:Lymphocyte Activation; D019860:Lymphocyte Specific Protein Tyrosine Kinase p56(lck); D010766:Phosphorylation; D011505:Protein-Tyrosine Kinases / Q000502:physiology; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000502:physiology*
D011505:Protein-Tyrosine Kinases; D019860:Lymphocyte Specific Protein Tyrosine Kinase p56(lck); D017493:Leukocyte Common Antigens