Use of naltrexone for treatment of psychogenically induced dermatoses in five zoo animals.
Naltrexone was used successfully in controlling self-mutilation behavior in 3 zoo animals from 2 families (Felidae and Sciuridae). It had no effect on 2 other zoo animals from 2 families (Canidae and Ursidae). Long-term administration of glucocorticoids was not satisfactory in controlling the behaviors, and concerns were raised about potential long-term adverse effects, especially with regard to fertility. Detrimental effects were not noticed in any of the zoo animals treated with naltrexone. Two males successfully sired healthy offspring.
Denver Zoological Gardens, City Park, CO 80205.
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Kenny
D000818:Animals; D001522:Behavior, Animal; D002335:Carnivora; D005260:Female; D008297:Male; D009271:Naltrexone / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use; D012376:Rodent Diseases / Q000188:drug therapy* / Q000209:etiology; D012589:Sciuridae; D016728:Self-Injurious Behavior / Q000188:drug therapy; D012871:Skin Diseases / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D001503:Ursidae
D009271:Naltrexone; D011241:Prednisone