2,5-Dihydroxy-7-methoxy-6,8-dimethylflavan-3-one a novel flavonoid from Leptospermum scoparium: in vitro affinity to the benzodiazepine binding site of the GABAA receptor-chloride channel complex.
Institut für Pharmazeutische biologie der Philipps-Universität Marburg.
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D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000378:metabolism; D018118:Chloride Channels / Q000378:metabolism*; D044950:Flavanones; D005419:Flavonoids / Q000493:pharmacokinetics*; D066298:In Vitro Techniques; D008024:Ligands; D008970:Molecular Weight; D009520:New Zealand; D010936:Plant Extracts / Q000032:analysis / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D011963:Receptors, GABA-A / Q000378:metabolism*
C091673:2,5-dihydroxy-7-methoxy-6,8-dimethylflavan-3-one; D018118:Chloride Channels; D044950:Flavanones; D005419:Flavonoids; D008024:Ligands; D010936:Plant Extracts; D011963:Receptors, GABA-A