[Contrast products in magnetic resonance imaging].
Contrast agents MRI (Magnetic Resonance Imaging) have been developed to improve the diagnostic information obtained by this technic. They mainly interact on T1 and T2 parameters and increase consequently normal to abnormal tissues contrast. The paramagnetic agents which mainly act on longitudinal relaxation rate (T1) are gadolinium complexes for which stability is the main parameter to avoid any release of free gadolinium. The superparamagnetic agents that decrease signal intensity by an effect on transversal relaxation rate (T2) are developed for liver, digestive and lymph node imaging. Many area of research are now opened for optimal use of present and future contrast agents in MRI.
Bonnemain
B
B
Laboratoire Guerbet, BP 50400, Roissy-Charles-de-Gaulle.
D003287:Contrast Media / Q000145:classification* / Q000493:pharmacokinetics; D004355:Drug Stability; D008279:Magnetic Resonance Imaging; D013113:Spin Labels
D003287:Contrast Media; D013113:Spin Labels
Les produits de contraste en imagerie de résonance magnétique.