Bronchoscopic therapy in patients with intraluminal typical bronchial carcinoid.
OBJECTIVE
To study the efficacy of bronchoscopic therapy in patients with intraluminal typical bronchial carcinoid.


METHODS
Retrospective analysis of the data of patients with bronchial carcinoid, treated primarily with bronchoscopic techniques such as Nd-YAG laser in various hospitals in the Netherlands.


METHODS
Eleven patients with pulmonary complaints, ages 22 to 60 years, who were found to have intraluminal typical bronchial carcinoid. BRONCHOSCOPIC INTERVENTIONS: Six of the 11 patients received Nd-YAG laser treatments, one received Nd-YAG laser plus photodynamic therapy, and the other four had mechanical tumor removal.


RESULTS
Six patients were surgically treated after bronchoscopic therapy. The resected specimens showed no residual carcinoid. Median follow-up has been 70 months (range, 9 to 170 months). Five patients were not surgically treated after bronchoscopic therapy. Follow-up has been 27 to 246 months (median, 47 months) without signs of recurrence.


CONCLUSIONS
In 11 patients with typical, intraluminal, bronchial carcinoids, bronchoscopic treatment seemed to result in excellent local control, with surgical proof of cure in 6 of 11 patients. Bronchoscopic approach may provide a tissue-sparing alternative for bronchoplastic surgery in a subset of patients with typical intraluminal bronchial carcinoids.
Department of Pulmonary Medicine, Free University Hospital Amsterdam, The Netherlands.
T G
TG
Sutedja
A J
AJ
Schreurs
R G
RG
Vanderschueren
B
B
Kwa
T S
TS
vd Werf
P E
PE
Postmus
D000328:Adult; D001984:Bronchial Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D001999:Bronchoscopy; D002276:Carcinoid Tumor / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy