Auditory brainstem responses in leptomeningeal metastatic spread. Presentation of 2 cases.
Auditory brainstem responses (ABRs) were recorded in 2 patients with hearing loss caused by leptomeningeal metastatic spread. These recordings showed similar characteristic findings. The absolute latencies of wave V and interwave latencies I-V were exceedingly increased. Definite effects on the wave morphology and latency of wave V were observed with the use of high repetition rates. It is surmised that the hearing loss caused by leptomeningeal metastatic spread is mainly an effect on the auditory nerve and/or the cochlear nucleus. ABR examination is of clinical value in detecting functional abnormalities resulting from leptomeningeal metastatic spread.
Funai
H
H
Department of Otolaryngology, Tokyo, Japan.
Hayase
A
A
Kitahara
N
N
Hosako
Y
Y
D000368:Aged; D001099:Arachnoid; D002648:Child; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006313:Hearing Loss, Central / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006320:Hearing Tests; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008527:Medulloblastoma / Q000150:complications* / Q000175:diagnosis / Q000556:secondary; D008577:Meningeal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000556:secondary; D010841:Pia Mater