Keloid formation from levonorgestrel implant (Norplant System) insertion.
It is possible that women of certain ethnic backgrounds, specifically those more prone to keloid formation, are also more prone to the insertion site complications of levonorgesterel implants. Failure to recognize the potential for this complication and to provide adequate guidance to the patient could result in unwarranted cost and complications. It is possible that intralesional steroid injection at the first sign of a local reaction will minimize the formation of a keloid; however, specific research will need to be done before a change in practice can be recommended.
Department of Family Practice, University of California, Davis 95817.
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D000328:Adult; D001768:Blister / Q000139:chemically induced; D003875:Drug Eruptions / Q000209:etiology*; D004343:Drug Implants / Q000009:adverse effects; D005260:Female; D006801:Humans; D007627:Keloid / Q000139:chemically induced* / Q000208:ethnology; D016912:Levonorgestrel / Q000009:adverse effects*
D004343:Drug Implants; D016912:Levonorgestrel