[Correlation between bronchoalveolar lavage fluid angiotensin converting enzyme levels and T cell subsets in patients with sarcoidosis].
BALF ACE levels were assayed in patients with sarcoidosis, and their correlation with lymphocyte percentage and TH/Ts ratio in BALF were analysed. The results showed a positive correlation (r = 0.4453, P < 0.05; r = 0.7085, P < 0.01). BALF ACE level was decreased as patients with active sarcoidosis improved clinically, indicating that BALF ACE level may be a sensitive biological parameter in the diagnosis and disease activity assessment of sarcoidosis.
Li
Z H
ZH
Respiratory Diseases Institute China Medical University, Shenyang.
Li
Y L
YL
Hou
X M
XM
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D016516:CD4-CD8 Ratio; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*; D017565:Sarcoidosis, Pulmonary / Q000201:enzymology* / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology*
D015415:Biomarkers; D007703:Peptidyl-Dipeptidase A