[Resistance to activated protein C, so-called APC resistance: the first two cases in Slovakia].
For the anticoagulant action of activated protein C (APC) in addition to protein S another newly detected cofactor is essential. Its deficiency is described as APC-resistance. This defect which is closely associated with the molecule of the factor V seems to be the most frequent cause of thrombophilia. The authors describe two patients where APC-resistance was diagnosed for the first time in Slovakia.
Klinika hematológie a transfuziológie MFN Martin.
J
J
Hudecek
J
J
Ivánková
P
P
Kubisz
D000328:Adult; D005260:Female; D006801:Humans; D020151:Protein C Deficiency; D013927:Thrombosis / Q000097:blood*
Rezistence na aktivovaný protein C, tzv. APC-rezistence: první dva prípady na Slovensku.