[Demonstration of molecular combinations of alpha cyclodextrin (ACD) with dioctanoyl glycerol].
The molecular association of dioctanoyl glycerol (DOG) with the natural alpha cyclodextrin molecule (ACD) was studied using small unilamellar vesicles (SUV) by proton and 13C NMR. While no classic inclusion complex was found, a molecular association exists, leading to the formation of an insoluble precipitate. The possibility of a polar head group implication is discussed about the dimyristoyl phosphatidyl choline model.
Département de Biophysique, Centre de Recherches du Service de Santé de Armées, La Tronche.
F
F
Fauvelle
M
M
Idiri
J C
JC
Debouzy
D003505:Cyclodextrins / Q000302:isolation & purification*; D004075:Diglycerides / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy
D003505:Cyclodextrins; D004075:Diglycerides; C044295:1,2-dioctanoylglycerol
Mise en évidence des associations moléculaires des alpha cyclodextrines (ACD) avec le dioctanoyl glycérol.