[Metabolism of neutral lipids in hemopoietic organs and in the liver of mice with alloxan diabetes].
The metabolism of neutral lipids (free and ester-bound cholesterols, mono-, di- and triacylglycerides) was greatly impaired in liver, spleen, thymus tissues and ileocecal lymph nodes of BALB/c mice with subacute alloxan diabetes (content of sugar in blood was no less than 14 mmol/l) as shown by 3H-acetate and 14C-palmitate incorporation into the corresponding lipid fractions. The rate of neutral lipid turnover was specifically decreased in all the tissues studied. However, a considerable accumulation of these lipid fractions was found in thymus tissue. Incorporation of labelled palmitate into triacylglycerides was increased in the spleen but without obesity of the organ.
Kozlov
Iu A
IuA
Saprykina
E V
EV
Baĭkov
A N
AN
Novitskiĭ
V V
VV
D000496:Alloxan; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism*; D008198:Lymph Nodes / Q000378:metabolism*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D013154:Spleen / Q000378:metabolism*; D013950:Thymus Gland / Q000378:metabolism*
D000496:Alloxan
Metabolizm neĭtral'nykh lipidov v organakh gemopoéza i v pecheni mysheĭ s alloksanovym diabetom.