Use of naltrexone for treatment of psychogenically induced dermatoses in five zoo animals.
Naltrexone was used successfully in controlling self-mutilation behavior in 3 zoo animals from 2 families (Felidae and Sciuridae). It had no effect on 2 other zoo animals from 2 families (Canidae and Ursidae). Long-term administration of glucocorticoids was not satisfactory in controlling the behaviors, and concerns were raised about potential long-term adverse effects, especially with regard to fertility. Detrimental effects were not noticed in any of the zoo animals treated with naltrexone. Two males successfully sired healthy offspring.
Kenny
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Denver Zoological Gardens, City Park, CO 80205.
D000818:Animals; D001522:Behavior, Animal; D002335:Carnivora; D005260:Female; D008297:Male; D009271:Naltrexone / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use; D012376:Rodent Diseases / Q000188:drug therapy* / Q000209:etiology; D012589:Sciuridae; D016728:Self-Injurious Behavior / Q000188:drug therapy; D012871:Skin Diseases / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D001503:Ursidae
D009271:Naltrexone; D011241:Prednisone