[Treatment of pylethrombosis with alteplase. Description of a clinical case].
The authors report a case of venous pylethrombosis of the proximal splanchnic circuit treated with rt-PA (alteplase) for the first two days and later associated with high doses of heparin. rt-PA demonstrated a good level of efficacy with the partial resolution of the thrombus already after the first administration and in spite of the late commencement of therapy.
Sassoli
S
S
Unità Operativa di Medicina Malattie Infettive, Ospedale S. Maria Sopra i Ponte, Arezzo.
Maestrini
R
R
Occhini
U
U
Caremani
M
M
D000328:Adult; D004359:Drug Therapy, Combination; D005260:Female; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D008991:Monitoring, Physiologic; D011169:Portal Vein / Q000000981:diagnostic imaging; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use*; D014463:Ultrasonography
D006493:Heparin; D010959:Tissue Plasminogen Activator
Trattamento di una piletrombosi con alteplase. Descrizione di un caso clinico.