Renal complications during pregnancy in a patient with diabetes mellitus.
We present a 23-year-old woman with a 7-year history of insulin-dependent diabetes mellitus (IDDM) who became pregnant. At the 23rd week of pregnancy she exhibited the signs and symptoms (hypertension, edema, proteinuria) of both diabetic nephropathy and preeclampsia. A cesarean section was successfully performed. The proteinuria persisted for more than 3 months after delivery. Renal biopsy confirmed the diagnosis of diabetic glomerulosclerosis together with the renal findings attributable to preeclampsia. The rapid acceleration of diabetic nephropathy in this patient was attributed to preeclampsia. We therefore recommend that patients with DM be followed closely during pregnancy in an attempt to prevent the acceleration of renal damage by preeclampsia.
Division of Nephrology, Nagoya Daini Red Cross Hospital, Japan.
A
A
Yoshida
K
K
Morozumi
A
A
Takeda
K
K
Koyama
T
T
Oikawa
D000328:Adult; D002585:Cesarean Section; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000209:etiology* / Q000473:pathology; D018450:Disease Progression; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000473:pathology; D011225:Pre-Eclampsia / Q000150:complications; D011247:Pregnancy; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics