[Acquired mid-dermal elastolysis].
Sixteen cases of acquired mid-dermal elastolysis have been reported in the literature. In 1977, Shelley identified this type of elastolysis as a separate entity and described three variants: post-inflammatory elastolysis with cutis laxa predominates in facial areas in African children. The initial inflammatory lesions are replaced by rough wrinkling of the skin; post-inflammatory elastolysis without cutis laxa; non-inflammatory elastolysis without cutis laxa as mid-dermal elastolysis. It is difficult nevertheless to classify certain cases reported in the literature. This would suggest that there is in reality a continuum of acquired elastolysis which could be classed according to a scale of decreasing initial inflammation. The non-inflammatory pole would represent mid-dermal elastolysis. The common features of the different types of elastolysis are dominated by the absence of a causative agent in most cases, unknown pathogenesis and the fact that the empirical treatments which have been used have been ineffective.
Service de Dermatologie, CHU Xavier-Bichat, Paris.
S
S
Maghraoui
M
M
Grossin
B
B
Crickx
P
P
Blanchet
S
S
Belaïch
D000328:Adult; D000368:Aged; D003483:Cutis Laxa / Q000175:diagnosis; D003937:Diagnosis, Differential; D004547:Elastic Tissue; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000175:diagnosis* / Q000473:pathology
L'élastolyse acquise du derme moyen.