Pulmonary hyalinizing granuloma with Castleman's disease.
A case of pulmonary hyalinizing granuloma (PHG) with Castleman's disease in a 43-year-old man is presented. He was asymptomatic, but the disease was recognized due to a routine chest roentgenographic study. Anemia, multiple lymphadenopathy, hypoalbuminemia and polyclonal hypergamma-globulinemia were observed. Histological examination of cervical lymph nodes revealed the plasma cell type of Castleman's disease. The diagnosis of PHG was confirmed by video-assisted thoracoscopical lung biopsy, and the immuno-histochemical staining of lamellar fibrosis for types I and III collagen was positive.
Department of Internal Medicine, National Kinki-Chuo Hospital for Chest Diseases, Osaka.
S
S
Atagi
M
M
Sakatani
M
M
Akira
S
S
Yamamoto
E
E
Ueda
D000328:Adult; D005871:Castleman Disease / Q000150:complications* / Q000175:diagnosis; D006099:Granuloma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000150:complications* / Q000175:diagnosis; D008198:Lymph Nodes / Q000473:pathology; D008297:Male