Structure and absolute configuration of palmonine F, a new eunicellin-based diterpene from the gorgonian Eunicella verrucosa.
In addition to the palmonines reported in a previous communication, a new eunicellin-type diterpene, palmonine F [1], has been isolated from the gorgonian Eunicella verrucosa. Its structure was elucidated by interpretation of spectral data and chemical interconversions and its absolute configuration was established using the Mosher's method. The cytotoxicity assay results for the palmonines are reported.
Departamento de Química Orgánica, Facultad de Ciencias del Mar, Universidad de Cádiz, Puerto Real, Spain.
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Ortega
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Zubía
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Salva
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D003063:Cnidaria; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D009904:Optical Rotation
D004224:Diterpenes; D007202:Indicators and Reagents; C091982:palmonine F