Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. I. Taxonomy, fermentation and biological activity.
Actinomycete culture LL-D37187 has been found to produce the new polyether antibiotic martinomycin. Taxonomic studies, including morphological, physiological, and cell wall chemistry analyses, revealed that culture LL-D37187 is a novel streptomycete species, and the proposed name is Streptomyces salvialis. Martinomycin exhibits activity against the Southern Army Worm (Spodoptera eridania) and Gram-positive bacteria.
Natural Products Research Section, American Cyanamid Company, Pearl River, NY 10965.
V S
VS
Bernan
D A
DA
Montenegro
J J
JJ
Goodman
M R
MR
Alluri
G T
GT
Carter
D R
DR
Abbanat
C J
CJ
Pearce
W M
WM
Maiese
M
M
Greenstein
D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001156:Artemia / Q000187:drug effects; D004987:Ethers / Q000494:pharmacology; D005285:Fermentation; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007306:Insecticides / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning; D015394:Molecular Structure; D018411:Spodoptera; D013302:Streptomyces / Q000145:classification / Q000378:metabolism* / Q000648:ultrastructure
D000900:Anti-Bacterial Agents; D004987:Ethers; D007306:Insecticides; C091815:martinomycin