[Treatment of osteoporosis by the gynecologist].
At least one of four women is suffering from osteoporosis with fractures of vertebrae, forearm or hip. Maintenance of bone-mass is a crucial argument for long-term estrogen replacement for prophylaxis of osteoporosis. 2 mg estradiol or 0.625 mg conjugated estrogens, or 50-100 micrograms estradiol percutaneously are equally sufficient for prevention of osteoporosis. The additional use of a progestagen in women with intact uterus may support the antiresorptive effects of estrogens. Improvement of patients' compliance of estrogen substitution--administered today in only 25% of postmenopausal women in Germany--by sufficient information upon estrogen replacement therapy provided by the medical community is an awarding task for physicians and scientists engaged in the field of menopause and prevention of osteoporosis.
Schneider
H P
HP
Zentrum für Frauenheilkunde, Westfälischen Wilhelms-Universität Münster.
Dören
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D000279:Administration, Cutaneous; D000284:Administration, Oral; D000368:Aged; D015519:Bone Density / Q000187:drug effects; D004958:Estradiol / Q000008:administration & dosage / Q000009:adverse effects; D015914:Estrogen Replacement Therapy; D004966:Estrogens, Conjugated (USP) / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D005858:Germany; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy* / Q000209:etiology; D011374:Progesterone / Q000008:administration & dosage / Q000009:adverse effects
D004966:Estrogens, Conjugated (USP); D011374:Progesterone; D004958:Estradiol
Die Behandlung der Osteoporose in der Hand des Gynäkologen.