In vitro antibacterial screening of Cryptolepis sanguinolenta alkaloids.
The ethanol and aqueous crude extracts and five alkaloids isolated from the roots of Crytolepis sanguinolenta (Lindl.) Schlechter were screened for antibacterial activity against 7 reference strains by the twofold serial broth microdilution assay. The ethanol extract and the alkaloids cryptolepine and cryptoheptine inhibited the growth of all strains tested except that of Pseudomonas aeruginosa.
Department of Pharmacognosy, Faculty of Pharmacy, University of Lisbon, Portugal.
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Paulo
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Duarte
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Gomes
D000470:Alkaloids / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D066298:In Vitro Techniques; D016488:Medicine, African Traditional; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal
D000470:Alkaloids; D010936:Plant Extracts