The prognostic significance of urinary albumin in Polynesians with non-insulin-dependent diabetes.
Polynesian (59 Maori and 30 Pacific Island) patients were identified from two diabetes clinic registers and followed for a mean of 4.8 years, in order to determine the prognostic significance of urinary albumin excretion. Events were defined as death or entry onto a renal replacement programme. Fourteen events occurred during the period of follow-up. Urinary albumin/creatinine ratio was treated as a continuous variable in a proportional hazards analysis. A 10-fold increase in albumin/creatinine ratio was associated with a 5-fold increase in the risk of an event (95% C.I. = 2.05-12.09). In conclusion, elevated urinary albumin/creatinine predicted mortality and renal morbidity in Maori and Pacific Island patients with non-insulin-dependent diabetes.
Lunt
H
H
Diabetes Services, Christchurch Hospital, New Zealand.
Graham
P J
PJ
Jury
D R
DR
Lim
C W
CW
Crooke
M J
MJ
Smith
R B
RB
Dunn
P J
PJ
D000419:Albuminuria; D003924:Diabetes Mellitus, Type 2 / Q000401:mortality / Q000652:urine*; D003928:Diabetic Nephropathies / Q000453:epidemiology / Q000401:mortality / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009520:New Zealand; D010139:Pacific Islands / Q000208:ethnology; D011237:Predictive Value of Tests; D011379:Prognosis; D016016:Proportional Hazards Models; D012042:Registries; D006435:Renal Dialysis; D044465:White People