A possible explanation for growth hormone resistance in chronic renal failure.
Perhaps the liver in renal failure significantly alters its pH in order to attempt to maintain homeostasis. This alteration might explain the growth hormone resistance found in children with chronic renal failure.
Endocrinology Department, Brooke Army Medical Center, San Antonio, Texas 78234.
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D000137:Acid-Base Imbalance / Q000150:complications; D002675:Child, Preschool; D006130:Growth Disorders / Q000150:complications; D013006:Growth Hormone / Q000378:metabolism*; D006706:Homeostasis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007676:Kidney Failure, Chronic / Q000150:complications*; D008099:Liver / Q000378:metabolism; D011986:Receptors, Somatotropin / Q000378:metabolism
D011986:Receptors, Somatotropin; D013006:Growth Hormone