[Lung transplantation. Indications, preoperative evaluation and postoperative treatment].
Thirty-six heart-lung and lung transplantations have been performed in Denmark from January 1992 to January 1994. Heart-lung transplantations was initially carried out in patients with pulmonary vascular diseases. Single lung, double lung and heart-lung transplantation have become therapeutical alternatives and the indications have been expanded to terminal patients with pulmonary diseases. Careful selection of patients and donors, careful surgical techniques and a stringent immunosuppressive treatment have minimized the perioperative mortality. Daily lung function measurements, transbronchial biopsies and bronchoalveolar lavage have created possibilities for an early and safe diagnosis of infections and rejections. A high frequency of obliterative bronchiolitis with loss of pulmonary function is still a serious and unsolved problem. Intensive investigations with the aim of understanding, preventing and treating obliterative bronchiolitis are going on.
Rigshospitalet, København.
U G
UG
Svendsen
S
S
Aggestrup
J
J
Aldershvile
H C
HC
Arendrup
S A
SA
Mortensen
J J
JJ
Thiis
G
G
Petterson
D001989:Bronchiolitis Obliterans / Q000209:etiology; D006084:Graft Rejection; D016041:Heart-Lung Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008168:Lung / Q000503:physiopathology; D016040:Lung Transplantation / Q000009:adverse effects / Q000379:methods; D011014:Pneumonia / Q000209:etiology / Q000382:microbiology; D011182:Postoperative Care; D011300:Preoperative Care; D013902:Radiography, Thoracic
D007166:Immunosuppressive Agents
Lungetransplantation. Indikationer, proeoperativ bedømmelse og postoperativ behandling.