[Results of collalysine treatment of children with adhesive otitis media].
Upon a clinical and audiological examination of 92 children with adhesive otitis media the patients were assigned to standard treatment or to treatment with a new proteolytic enzyme collalysin. The indications to these therapies were based on the degree of cicatrization, hearing loss and the disease duration. Conventional treatment yielded effect only in the disease duration less than 3 years, an insignificant hearing loss and nonsevere tympanic scars. Otoscopic, acoustic and tympanometric improvement after collalysin electrophoresis was observed in marked scars of the tympanic membrane, in a hearing loss by more than 30 dB, in shorter duration of the disease. 80% of the patients on collalysin functionally benefited from the treatment.
A A
AA
Dantsov
L M
LM
Kovaleva
I F
IF
Grigor'eva
M V
MV
Drozdova
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005500:Follow-Up Studies; D006801:Humans; D003012:Microbial Collagenase / Q000627:therapeutic use*; D010033:Otitis Media / Q000175:diagnosis / Q000188:drug therapy*; D013997:Time Factors
D003012:Microbial Collagenase
Rezul'taty lecheniia kollalizinom deteĭ s adgezivnym srednim otitom.