[The Neisseria meningitidis serotypes and subtypes circulating among bacterial carriers in Moscow (1989-1991)].
N. meningitidis strains isolated from 218 healthy carriers in 1989-1991 in closed communities of adults, irrespective of cases of meningococcal infection registered in these communities, were characterized with a variety of different type and subtype antigens. Only in 139 strains (63.76%) their types and/or subtypes could be determined with the use of a set of 6 serotypes and 11 subtypes of monoclonal antibodies. 26 group B strains and 31 group C strains had multiple antigenic composition. 13 group A strains were found to be more homogeneous: 8 of them, isolated in one area, belonged, according to Dr. Achtman's data, to a definite clone VI-1, heretofore unknown. No prevailing serotype/subtype could be revealed, which reflected the wide heterogeneity of N. meningitidis at the period of the decrease of morbidity in meningococcal infection. The observed stability of serotype/subtype of strains, isolated from the same carriers and circulating in the same communities, suggests that the serotype/subtype of N. meningitidis is a valuable epidemiological marker.
M Kh
MKh
Gorlina
N N
NN
Kostiukova
I B
IB
Mil'dzikhova
T F
TF
Chernysheva
A I
AI
Mishina
T A
TA
Skirda
H
H
Kayhty
D000328:Adult; D002353:Carrier State / Q000382:microbiology*; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000032:analysis; D008589:Meningococcal Infections / Q000382:microbiology*; D009031:Moscow; D009113:Muramidase / Q000037:antagonists & inhibitors; D009345:Neisseria meningitidis / Q000145:classification* / Q000201:enzymology / Q000302:isolation & purification / Q000472:pathogenicity; D012703:Serotyping; D014505:Urban Population
D009113:Muramidase; D006821:Hyaluronoglucosaminidase
Serotipy i subtipy Neisseria meningitidis, tsirkuliruiushchikh sredi bakterionositeleĭ v Moskve (1989--1991 gg.).