Ecogenetic and pharmacogenetic studies in Hungary.
12 population groups of Hungary, 1514 individuals altogether, have been studied for polymorphisms of alpha 1antitrypsin, serum cholinesterase, paraoxonase and delta-aminolevulinic acid dehydrase, N-acetyltransferase variation and aldehyde dehydrogenase deficiency. A possible relationship between their allele frequencies and environmental factors in the context of ecogenetic and pharmacogenetic phenomena in Hungary is discussed.
Institute of Human Genetics, University of Hamburg, Germany.
H G
HG
Benkmann
L
L
Timar
I
I
Szentesi
U
U
Wimmer
E
E
Lohmann
A
A
Czeizel
H W
HW
Goedde
D000293:Adolescent; D000328:Adult; D000444:Aldehyde Dehydrogenase / Q000172:deficiency / Q000235:genetics*; D001191:Arylamine N-Acetyltransferase / Q000172:deficiency / Q000235:genetics*; D043303:Aryldialkylphosphatase; D002802:Cholinesterases / Q000097:blood / Q000172:deficiency / Q000235:genetics*; D004950:Esterases / Q000172:deficiency / Q000235:genetics*; D005260:Female; D006801:Humans; D006814:Hungary / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011110:Polymorphism, Genetic; D000623:Porphobilinogen Synthase / Q000172:deficiency / Q000235:genetics*; D000515:alpha 1-Antitrypsin / Q000235:genetics*; D019896:alpha 1-Antitrypsin Deficiency
D000515:alpha 1-Antitrypsin; D000444:Aldehyde Dehydrogenase; D001191:Arylamine N-Acetyltransferase; D004950:Esterases; D002802:Cholinesterases; D043303:Aryldialkylphosphatase; D000623:Porphobilinogen Synthase