The use of ciprofloxacin in veterinary proprietary products of enrofloxacin.
A 3-mo chemical surveillance of 5 proprietary products of enrofloxacin for veterinary use was carried out. In all, 50 samples were analyzed by thin-layer chromatography and UV-Vis spectroscopy. Only the original brand of enrofloxacin (BAYTRIL) contained 5% of the drug while the 40 samples from the other 4 products contained 7.5% ciprofloxacin. A word of caution is given for the indiscriminate use of fluoroquinolones in veterinary medicine.
Sumano
L H
LH
Department of Pharmacology, School of Veterinary Medicine, Universidad Nacional Autonoma de Mexico (UNAM), Mexico City.
Gomez
R B
RB
Gracia
M I
MI
Ruiz-Ramirez
L
L
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000592:standards; D002855:Chromatography, Thin Layer; D002939:Ciprofloxacin / Q000032:analysis*; D000077422:Enrofloxacin; D024841:Fluoroquinolones; D015363:Quinolones / Q000737:chemistry* / Q000592:standards; D012015:Reference Standards; D013056:Spectrophotometry, Ultraviolet; D014730:Veterinary Medicine / Q000592:standards*
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D000077422:Enrofloxacin; D002939:Ciprofloxacin