Tumor blood flow measured using dynamic computed tomography.
OBJECTIVE
A method for measuring the tumor blood flow (TBF) by means of dynamic computed tomography (DCT) was devised and investigated.


METHODS
Twenty-seven patients with superficial tumors underwent measurement of TBF by the new DCT method. For all of the 27 patients, the thermal clearance method was employed to measure the relative tumor blood flow (RTBF). For 16 patients, TBF was measured by oxygen-15-gas positron-emission tomography (PET). The TBF values measured by DCT were compared with the RTBF by the thermal clearance method and the TBF by PET.


RESULTS
The results demonstrated a linear relationship.


CONCLUSIONS
The newly devised DCT method yields reliable data in measuring TBF.
Department of Radiology, Kanto Central Hospital, Tokyo, Japan.
H
H
Hattori
T
T
Miyoshi
J
J
Okada
K
K
Yoshikawa
N
N
Arimizu
N
N
Hattori
D001810:Blood Volume; D002277:Carcinoma / Q000098:blood supply* / Q000000981:diagnostic imaging*; D003287:Contrast Media; D006801:Humans; D008198:Lymph Nodes / Q000098:blood supply / Q000000981:diagnostic imaging; D010104:Oxygen Radioisotopes; D011856:Radiographic Image Enhancement; D012039:Regional Blood Flow / Q000502:physiology; D015203:Reproducibility of Results; D013997:Time Factors; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed / Q000379:methods*
D003287:Contrast Media; D010104:Oxygen Radioisotopes