Nucleotide sequence of the Salmonella typhimurium trpR gene.
The sequence of the Salmonella typhimurium trpR gene and flanking DNA was determined on both strands. The DNA sequence predicts a polypeptide product of 108 amino acids with a molecular weight of 12,274 daltons. The TrpR protein of S. typhimurium differs by three amino acid residues from that of E. coli. The promoter/operator region of trpR is completely conserved between E. coli and S. typhimurium. The nucleotide sequence of the trpR sector of the S. typhimurium genome was 87.4% identical to the corresponding region of the E. coli genome. Within the protein coding segments of the two organisms, 94.4% of the amino acid residues were identical. In S. typhimurium, as in E. coli, there is a Palindromic Unit element (PU) between the translation termination triplet of trpR and that of a divergently oriented unidentified reading frame (URF-143). However, the PU segment of S. typhimurium is 85 nucleotides shorter than its E. coli counterpart.
Department of Biochemistry, Purdue University, West Lafayette, IN 47907-1153.
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Somerville
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D029968:Escherichia coli Proteins; D005798:Genes, Bacterial / Q000235:genetics; D008969:Molecular Sequence Data; D010641:Phenotype; D016133:Polymerase Chain Reaction; D012097:Repressor Proteins / Q000235:genetics*; D012486:Salmonella typhimurium / Q000235:genetics*
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; D012097:Repressor Proteins; C027190:TRPR protein, E coli; C081759:WrbA protein, E coli