Immune parameters in euthymic bipolar patients and normal volunteers.
Immune system parameters were investigated in euthymic bipolar patients and matched normal volunteers. A review of the existing literature suggested that bipolar patients might be more likely to demonstrate signs of immune activation. Serum-soluble interleukin-2 receptors, circulating phenotypic lymphocyte markers, levels were measured. Euthymic bipolar patients and normal volunteers did not differ or any of these measures. Furthermore, bipolar patients could not be differentiated by medication status or gender. In conclusion, there was no evidence of immune system activation in euthymic bipolar patients.
Department of Psychiatry, University of California at San Diego.
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Rapaport
D000328:Adult; D000911:Antibodies, Monoclonal; D015703:Antigens, CD / Q000276:immunology; D001714:Bipolar Disorder / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D005260:Female; D005434:Flow Cytometry; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007376:Interleukin-2 / Q000097:blood / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D006680:HLA Antigens; D007376:Interleukin-2