[Effect of crystal no. 4 of polygonum cuspidatum on the viability of island flaps with venous stasis: an experimental study].
The effects of crystal No. 4 of Polygonum cuspidatum on microcirculatory changes of island flaps in rats following resumption of blood flow after venous occlusion of six hours were observed with a special TV set with magnification of 500X. The pathological events and survival rate of flaps were recorded as well. The results showed that the survival rate, amount of open capillaries, amount of blood flow, and velocity of blood flow of flaps treated by crystal No. 4 of polygonum cuspidatum were much higher than those of untreated control flaps. The white thrombosis and endothelial damage of dermal vessels were alleviated by administration of crystal No. 4 of polygonum cuspsidatum. The experiment also showed that there were no differences between flaps treated with crystal No. 4 of polygonum cuspidatum preoperatively and flaps treated with it postoperatively.
Luo
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Department of Plastic Surgery, Nanfang Hospital, First Military Medical University, Guangzhou.
Luo
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D000818:Animals; D001783:Blood Flow Velocity / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006085:Graft Survival / Q000187:drug effects*; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000098:blood supply*; D013524:Surgical Flaps
D004365:Drugs, Chinese Herbal