Clinical sequelae of overt non-compliance with psychotropic agents.
A group of 487 patients admitted to Eastern State Hospital in Lexington, Kentucky, during a 3-month period were prospectively followed to determine the incidence of psychotropic medication refusal, unique characteristics of refusers, factors leading to refusal, and clinical outcome of those who refused. Patients who refused any dose(s) of psychotropic medications were identified within 24 hours of refusal. For patients who refused for 24 hours or more, the psychiatrist was asked to complete a 4-item questionnaire. Our data indicate that medication refusal leads to poorer clinical outcomes, as measured by length of hospitalization and incidence and duration of restraint episodes.
College of Pharmacy, University of Kentucky, Lexington 40536.
R A
RA
Littrell
A G
AG
Mainous
F
F
Karem
W R
WR
Coyle
C M
CM
Reynolds
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy* / Q000523:psychology; D011446:Prospective Studies; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D016312:Treatment Refusal
D011619:Psychotropic Drugs