[The effect of the characteristics of the interaction of their determinant of virulence with the metabolic and specific mechanisms of immunity on the persistence of infectious causative agents].
The persistence of the causative agents of infections depends on the effectiveness of the function of their virulence determinants ensuring their nutrition in the host body and resistance to its nonspecific and specific mechanisms of protection. The presence of antigens, effective mechanisms of antigenic reconstruction and, probably, the optimum ratio of strong and weak antigens in pathogenic microorganisms facilitates their persistence in the body of an immune host.
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Adamov
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D001419:Bacteria / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity*; D001424:Bacterial Infections / Q000276:immunology / Q000378:metabolism / Q000382:microbiology; D001427:Bacterial Toxins / Q000633:toxicity; D006801:Humans; D007109:Immunity; D014774:Virulence
D000942:Antigens, Bacterial; D001427:Bacterial Toxins
Vliianie na persistentsiiu vozbuditeleĭ infektsii osobennosteĭ vzaimodeĭstviia ikh determinant virulentnosti s metabolicheskimi i spetsificheskimi mekhanizmami immuniteta.