[Charcot-Marie-Tooth disease, dilated myocardiopathy and cardiac conduction disorders].
We describe the case of two brothers with Charcot-Marie-Tooth disease, dilated cardiomyopathy and disorders in the cardiac conduction. We review the literature in order to find physiological grounds for these associations. Despite the absence of consolidated data on this question, the genetic grounds could play some role here. In this sense, our cases contribute with the novelty that the disease affects two brothers. This has never been described before and could contribute, along with future observations, to clarify some etiopathogenic aspects of the disease.
Sevillano Fernández
J A
JA
Servicio de Medicina Interna I, Hospital General Universitario Gregorio Marañón, Madrid.
Paz Fraile
A
A
Cano Ballesteros
J C
JC
Villalba García
M V
MV
Otero Pérez
R
R
Gilsanz Fernández
C
C
D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D002607:Charcot-Marie-Tooth Disease / Q000175:diagnosis* / Q000235:genetics; D006327:Heart Block / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D013103:Spherocytosis, Hereditary / Q000175:diagnosis / Q000235:genetics
Enfermedad de Charcot-Marie-Tooth, miocardiopatía dilatada y trastornos de la conducción cardiaca.