Spatiotemporal distribution of protein kinase and phosphatase activities.
Reversible protein phosphorylation plays an essential role in controlling cellular functions. Accumulating evidence indicates that the subcellular distribution of protein kinase and phosphatase activities is organized dynamically. The spatiotemporal dynamics of kinase and phosphatase activities appears to account for the elaborate coordination of the cellular functions achieved by protein phosphorylation and dephosphorylation.
Department of Neurophysiology, Tokyo Metropolitan Institute of Gerontology, Japan.
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N
Inagaki
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M
Ito
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T
Nakano
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Inagaki
D002453:Cell Cycle / Q000502:physiology; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*; D013997:Time Factors
D011494:Protein Kinases; D010744:Phosphoric Monoester Hydrolases