Singlet oxygen generation by Photofrin in homogeneous and light-scattering media.
The singlet oxygen quantum yield (phi delta) for Photofrin solubilized by Triton X-100 was measured in homogeneous and light-scattering media using the photosensitized inactivation of lysozyme as an internal actinometer. Higher values of phi delta at 630 nm than at 514 nm are attributed to the formation of a far-red-absorbing photosensitizing photoproduct.
Wenske Laser Center, Ravenswood Hospital Medical Center, Chicago, IL 60640.
L R
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Jones
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Grossweiner
D001386:Azides / Q000494:pharmacology; D003624:Darkness; D004307:Dose-Response Relationship, Radiation; D007093:Imidazoles / Q000494:pharmacology; D007700:Kinetics; D008027:Light; D016982:Micrococcus luteus / Q000201:enzymology; D009113:Muramidase / Q000037:antagonists & inhibitors*; D010100:Oxygen; D011166:Porphyrins / Q000737:chemistry* / Q000494:pharmacology; D012542:Scattering, Radiation; D026082:Singlet Oxygen; D013482:Superoxide Dismutase / Q000494:pharmacology
D001386:Azides; D007093:Imidazoles; D011166:Porphyrins; D026082:Singlet Oxygen; C029899:imidazole; D013482:Superoxide Dismutase; D009113:Muramidase; D010100:Oxygen