Bilateral optic neuritis with branch retinal artery occlusion associated with vaccination.
A case of a 40-year old marine with bilateral optic neuritis and a branch retinal artery occlusion after vaccination is presented. Blood investigations showed no abnormalities. Cerebrospinal fluid studies revealed a lymphocytic pleocytosis and IgG antibodies against hepatitis A and rabies. Computerized tomography and magnetic resonance imaging of the brain were negative. A diagnosis of vaccine-induced auto-immune demyelinative optic neuritis was made. The clinical picture improved after systemic corticosteroid treatment.
Department of Ophthalmology, Central Military Hospital, Utrecht, The Netherlands.
E J
EJ
van de Geijn
R
R
Tukkie
L A
LA
van Philips
H
H
Punt
D000328:Adult; D001327:Autoimmune Diseases / Q000134:cerebrospinal fluid / Q000209:etiology; D003711:Demyelinating Diseases / Q000134:cerebrospinal fluid / Q000209:etiology; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D018655:Lymphocyte Count; D008297:Male; D009902:Optic Neuritis / Q000134:cerebrospinal fluid / Q000209:etiology*; D011820:Rabies virus / Q000276:immunology; D015356:Retinal Artery Occlusion / Q000134:cerebrospinal fluid / Q000209:etiology*; D014611:Vaccination / Q000009:adverse effects*; D014612:Vaccines / Q000009:adverse effects*
D007074:Immunoglobulin G; D014612:Vaccines