High hydrostatic pressures in traumatic joints require elevated synovial capillary pressure probably associated with arteriolar vasodilatation.
Three out of the four Starling pressures were determined at arthroscopy of traumatic effusions of the knee. The range of the joint fluid hydrostatic pressure Pjoint was 5-83 cmH2O (0.5-8.1 kPa, 4-61 mmHg), that of the colloid osmotic pressure difference COPplasma-COPjoint 0-21.7 cmH2O. In 11 of 15 cases the sum Pjoint+COP difference exceeded 32.6 cmH2O (3.19 kPa, 24 mmHg), a high estimate of average capillary pressure at the level of the heart. The number of 'exceeding' cases was 8/15 if only 80% of the COP difference was considered effective. Pjoint and the COP difference oppose filtration of fluid from plasma into joints, indicating that mean capillary pressure, the only Starling pressure not determined, was elevated unless the effusions were being resorbed back into the blood. The findings can be explained by tamponade compensated by arteriolar vasodilatation, suspected to be metabolically mediated.
Department of Pathology, Aurora Hospital, Finland.
J
J
Ahlqvist
A
A
Harilainen
K
K
Aalto
S
S
Sarna
M
M
Lalla
K
K
Osterlund
D000293:Adolescent; D000328:Adult; D000368:Aged; D001160:Arterioles / Q000502:physiology; D001182:Arthroscopy; D002196:Capillaries / Q000502:physiology; D002199:Capillary Permeability / Q000502:physiology; D002200:Capillary Resistance / Q000502:physiology; D002358:Cartilage, Articular / Q000098:blood supply / Q000378:metabolism / Q000503:physiopathology*; D002648:Child; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D006874:Hydrostatic Pressure; D007718:Knee Injuries / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D009995:Osmosis; D012044:Regression Analysis; D013583:Synovial Membrane / Q000098:blood supply* / Q000378:metabolism / Q000503:physiopathology; D014664:Vasodilation / Q000502:physiology*