Glutamine metabolism and utilization: relevance to major problems in health care.
Glutamine plays an important role in normal and pathophysiological states. In this review we describe the biochemical synthesis and degradation pathways of glutamine, as well as its utilization by the immune system and in rapidly dividing cells. Also discussed are glutamine behaviour in catabolic states and the therapeutic implications of this amino acid in total parenteral nutrition, digestive diseases and cancer.
Department of Urology, Bnai Zion Medical Center, Haifa, Israel.
B
B
Moskovitz
Y
Y
Katz
P
P
Singer
O
O
Nativ
B
B
Rosenberg
D000818:Animals; D005973:Glutamine / Q000378:metabolism* / Q000627:therapeutic use*; D006801:Humans; D007107:Immune System / Q000378:metabolism; D010289:Parenteral Nutrition, Total
D005973:Glutamine