Workshop studies on monoclonal antibodies reactive against porcine myeloid cells.
Investigators from eight laboratories analyzed the reactivity of 22 monoclonal antibodies (mAb) against porcine myeloid cells. Based on binding data, clustering analysis and inhibition studies, workshop mAb 74-22-15 (003) and 6F3 (007) were assigned a swine workshop cluster number 3 (SWC3). These mAb recognized macrophages and neutrophils; neutrophils; a monocyte/macrophage-specific mAb was not identified by this workshop.
Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan 66506.
F
F
Blecha
T
T
Kielian
D S
DS
McVey
J K
JK
Lunney
K
K
Walker
C R
CR
Stokes
K
K
Stevens
Y B
YB
Kim
R M
RM
Chu
T S
TS
Chen
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis*; D000918:Antibody Specificity / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D013552:Swine / Q000276:immunology*
D000911:Antibodies, Monoclonal