Age-related storage of iron in the liver of horses.
The non-haem iron concentration was estimated in post-mortem liver samples from 51 horses (age range 1-25 years). Two were normal and 49 had been suffering from conditions that were not expected to have had long-term effects on iron metabolism. Muscle samples (splenius and biceps femoris) from 23 of these horses were also analysed. There was a highly significant age-related increase in the non-haem iron concentration in the liver (r = 0.635, p < 0.001), but not in the muscles, in which the iron concentration was much lower than in the liver.
Department of Veterinary Clinical Studies, University of Edinburgh, Roslin, Midlothian, UK.
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Ramsay
D000375:Aging / Q000378:metabolism*; D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000378:metabolism; D006736:Horses / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D009132:Muscles / Q000378:metabolism
D007501:Iron