[Clinical experiences with local capsaicin treatment of chronic rhinopathy].
Eighty-four patients with clinical findings of hyperactive rhinopathy and no significant septal deviations were treated for 4 weeks with topical applications of capsaicin, which is the pungent substance in hot peppers. A neutral solution of low-dose capsaicin allowed patients to administer self-therapy without the need for local anesthesia. The majority of the patients showed a marked reduction in symptoms without significant side effects. Patients with (additional) allergic or medication-related rhinopathy seemed to show fewer therapeutic effects when compared to patients with only hyperactive rhinopathy.
Eberle
L
L
HNO-Klinik, Kantonsspital Luzern.
Glück
U
U
D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000336:Aerosols; D002211:Capsaicin / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D015508:Nasal Obstruction / Q000188:drug therapy* / Q000209:etiology; D012123:Pulmonary Ventilation / Q000187:drug effects; D012220:Rhinitis / Q000188:drug therapy* / Q000209:etiology; D012223:Rhinitis, Vasomotor / Q000188:drug therapy* / Q000209:etiology
D000336:Aerosols; D002211:Capsaicin
Klinische Erfahrungen mit lokaler Capsaicinbehandlung bei chronischer Rhinopathie.