[Thrombolytic therapy in thrombosis of prosthesis].
OBJECTIVE
To relate our experience with thrombolytic therapy in 8 patients with cardiac metal prosthesis complicated with thrombosis.


METHODS
Eight patients with clinical and echocardiographic diagnosis of cardiac valvar prosthesis thrombosis were treated.


RESULTS
The treatment efficacy was evaluated by clinical and echocardiographic improvement. The authors recognized improvement in all 8 patients. One case of hemorrhage was observed (coxo-femoral articulation). Late death were observed twice: 24 months after, sudden death and 30 months later by hemorrhagic stroke.


CONCLUSIONS
The results indicated that thrombolytic therapy is best way to treat patients with cardiac valve thrombosis, instead of surgical treatment.
Faculdade de Ciências Médicas da Santa Casa de Misericórdia de São Paulo.
V P
VP
Campagnucci
H Y
HY
Suzuki
R A
RA
Franken
L A
LA
Rivetti
D000328:Adult; D003328:Coronary Thrombosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010958:Plasminogen / Q000627:therapeutic use*; D013300:Streptokinase / Q000627:therapeutic use*; D015912:Thrombolytic Therapy
D010958:Plasminogen; D013300:Streptokinase
Terapêutica trombolítica nas tromboses de próteses mecânicas.