Microembolism from aortic aneurysm and ventricular thrombus: a complication of intravenous streptokinase.
Two patients sustained the rare complication of skin infarction following administration of intravenous streptokinase for acute myocardial infarction. We report evidence that dissolution of thrombus from an unsuspected source and subsequent microembolization of the skin may be responsible for this complication. In patients known to have an aortic aneurysm or ventricular thrombus, careful consideration should be given to the use of intravenous streptokinase following myocardial infarction.
University Department of Surgery, Hope Hospital, Salford, Manchester, UK.
J S
JS
Abraham
M
M
Wilson
V
V
Scripcariu
P C
PC
Barnes
R W
RW
Marcuson
D000368:Aged; D001014:Aortic Aneurysm / Q000150:complications; D006331:Heart Diseases / Q000150:complications; D006801:Humans; D007238:Infarction / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply* / Q000473:pathology; D013300:Streptokinase / Q000009:adverse effects*; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D013927:Thrombosis / Q000150:complications
D013300:Streptokinase