[The pathogenic properties of the causative agent and the immunological indices in an experimental Yersinia infection].
In experiments on guinea pigs infected enterally with Y. enterocolitica isogenic strains of serovar O3 (pYV+ and pYV-) with known properties some characteristics of their cell-mediated and humoral immunity and nonspecific resistance were studied. The development of the localized infectious process and the corresponding immune shifts were noted only in infection with plasmid-containing Yersinia; in these cases a rise in the amount of T- and B-lymphocytes in the immunocompetent organs (the thymus, the spleen, lymph nodes), an increase in the functional activity of T-lymphocytes, a decrease in the ingestive activity of neutrophils and in the levels of nonenzymatic cation proteins and leukocytes, as well as the active production of specific agglutinins, were registered.
Iushchuk
N D
ND
Alenushkina
T V
TV
Smirnov
I V
IV
Voskresenskaia
E A
EA
D000373:Agglutinins / Q000097:blood; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000918:Antibody Specificity; D001402:B-Lymphocytes / Q000276:immunology; D004195:Disease Models, Animal; D006168:Guinea Pigs; D008221:Lymphoid Tissue / Q000276:immunology; D012703:Serotyping; D013601:T-Lymphocytes / Q000276:immunology; D015009:Yersinia Infections / Q000276:immunology* / Q000382:microbiology*; D015008:Yersinia enterocolitica / Q000145:classification / Q000276:immunology* / Q000472:pathogenicity*
D000373:Agglutinins; D000907:Antibodies, Bacterial
Patogennye svoĭstva vozbuditelia i immunologicheskie pokazateli pri éksperimental'noĭ iersinioznoĭ infektsii.