Bronchopneumonia caused by Propionibacterium acnes.
Propionibacterium acnes was identified as the pathogen in a case of subacute lung infection by examination of an open lung biopsy specimen. The patient was a 65-year-old male with exacerbation of chronic lung disease. The organism was isolated in pure culture and was present in large numbers on Gram stain. Histological examination demonstrated active interstitial fibrosis; macrophages laden with Propionibacterium acnes antigen were revealed using a peroxidase-antiperoxidase stain. This is the first report of subacute infection of pulmonary tissue due to this organism.
Claeys
G
G
Department of Bacteriology, University Hospital, Ghent, Belgium.
Verschraegen
G
G
De Potter
C
C
Cuvelier
C
C
Pauwels
R
R
D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use; D001706:Biopsy; D001996:Bronchopneumonia / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000150:complications; D008297:Male; D011425:Propionibacterium acnes / Q000302:isolation & purification*
D000658:Amoxicillin