Decline in anti-HAV prevalence in the Milan area between 1958 and 1992.
We have compared the prevalence of antibody to HAV in sera collected from healthy individuals of Milan in 1958, 1977 and 1992 respectively. The results show a dramatic reduction of HAV circulation likely due to the considerable improvement of socioeconomic and hygienic living conditions which have occurred in Italy during the last decades.
Institute of Virology, University of Milan, Italy.
A R
AR
Zanetti
L
L
Romanò
E
E
Tanzi
A
A
Andreassi
A
A
Pozzi
A
A
Panuccio
T
T
Stroffolini
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D006506:Hepatitis A / Q000453:epidemiology / Q000276:immunology; D006508:Hepatitis Antibodies / Q000097:blood*; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D007223:Infant; D007558:Italy / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014505:Urban Population / Q000706:statistics & numerical data*
D006508:Hepatitis Antibodies