Successful treatment with cyclosporin A in a child with acquired pure amegakaryocytic thrombocytopenic purpura.
Idiopathic acquired pure amegakaryocytic thrombocytopenic purpura (APATP) in young patients (non-neonates) is a rare disorder with a variable clinical course. Cure is unusual. A 13.5-year-old boy with idiopathic APATP was treated with cyclosporin A. Apparently effective, the treatment resulted in the reappearance of marrow megakaryocytes and normalization of platelet count.
Peng
C T
CT
Department of Pediatrics, China Medical College Hospital, Taichung, Taiwan, Republic of China.
Kao
L Y
LY
Tsai
C H
CH
D000293:Adolescent; D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008533:Megakaryocytes; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000188:drug therapy*
D016572:Cyclosporine