[Effects of high iodine and high fluorine on children's intelligence and the metabolism of iodine and fluorine].
An investigation on children's intelligence and the metabolism of iodine and fluorine in high iodine and fluorine regions was carried out. The results were as follows. In high iodine and high fluorine areas, the thyroid enlargement prevalence rate among inhabitants and that among children were 3.8% and 29.8%, respectively. The dental fluorosis prevalence rate among inhabitants and that among children was 35.48% and 72.9%, respectively. The pupils' average intelligence quotient (IQ) was 76.67 +/- 7.75, slightly lower than the control point, but that of low intelligent pupils was 16.7%. The urinary iodine and urinary fluoride were 816.25 +/- 1.80 micrograms/L and 2.08 +/- 1.03 mg/L, respectively, markedly higher than the control point. The thyroid iodine-131 (131I) uptake rate was markedly lower than the control point. The values at 3 h and 24 h were 9.36 +/- 1.55% and 9.26 +/- 4.63%, respectively. The serum TSH was obviously higher than the control point. These results indicate that high iodine and high fluorine exert severe damage to human body.
Shandong Provincial Institute of Endemic Disease Control, Jinan.
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Yang
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Wang
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Guo
D000293:Adolescent; D002648:Child; D002681:China / Q000453:epidemiology; D005459:Fluorides / Q000378:metabolism*; D009050:Fluorosis, Dental / Q000453:epidemiology*; D006043:Goiter, Endemic / Q000453:epidemiology*; D006801:Humans; D007361:Intelligence Tests; D007455:Iodine / Q000378:metabolism*; D014881:Water Supply / Q000032:analysis*
D007455:Iodine; D005459:Fluorides