Depletion and recovery of the calcium-binding proteins calbindin and parvalbumin in the pigeon optic tectum following retinal lesions.
Retinal lesions in pigeons produced a marked depletion of somata and neuropil staining for both calbindin-D28k and parvalbumin immunoreactivities in the contralateral optic tectum. Calbindin-like immunoreactivity reappeared in some tectal layers by 6 weeks postlesion, whereas paravalbumin-like immunoreactivity recovered almost completely after 5 weeks. These data indicate that the retinal input may control the expression of calbindin and parvalbumin in the pigeon optic tectum.
Britto
L R
LR
Department of Physiology and Biophysics, University of São Paulo, Brazil.
Gobersztejn
F
F
Karten
H J
HJ
Cox
K
K
D000818:Animals; D064026:Calbindins; D010856:Columbidae; D003714:Denervation; D007839:Functional Laterality; D007150:Immunohistochemistry; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D010320:Parvalbumins / Q000032:analysis / Q000378:metabolism*; D012016:Reference Values; D012160:Retina / Q000502:physiology*; D064030:S100 Calcium Binding Protein G / Q000032:analysis / Q000378:metabolism*; D013477:Superior Colliculi / Q000378:metabolism*; D013997:Time Factors
D064026:Calbindins; D009419:Nerve Tissue Proteins; D010320:Parvalbumins; D064030:S100 Calcium Binding Protein G