Treatment of catheter-associated Candiduria with fluconazole irrigation.
OBJECTIVE
To examine the safety and efficacy of fluconazole in patients with a permanent nephrostomy or suprapubic catheter in the prevention of candiduria.


METHODS
Twenty patients with a nephrostomy or suprapubic catheter who had at least two positive urine cultures with a minimum of 15,000 col/mL Candida counts were studied. The catheters were irrigated with fluconazole solution prepared as 1 mg/mL with normal saline. Repeated urine cultures were obtained.


RESULTS
In 17 patients Candida was eradicated from the urine by the third to sixth day of irrigation. No side-effects were noted.


CONCLUSIONS
Fluconazole as an irrigant is effective and safe in the treatment of catheter-associated candiduria, which can be eliminated without changing the catheter.
Department of Urology, Uludağ University, Bursa, Turkey.
U
U
Simşek
H
H
Akinci
B
B
Oktay
I
I
Kavrama
M
M
Ozyurt
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002175:Candida / Q000302:isolation & purification; D002177:Candidiasis / Q000188:drug therapy* / Q000209:etiology; D004866:Equipment Contamination; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009403:Nephrostomy, Percutaneous / Q000009:adverse effects*; D007507:Therapeutic Irrigation; D014546:Urinary Catheterization / Q000009:adverse effects*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000209:etiology / Q000652:urine
D015725:Fluconazole