Magnetic resonance imaging and neuropathological findings in two patients with Creutzfeldt-Jakob disease.
We report 2 autopsy-proven patients with Creutzfeldt-Jakob disease (CJD) showing bilateral decreased signal intensity in the thalamus on T2-weighted images. On post-mortem examination, all affected areas showed the characteristic features of CJD, such as neuronal loss, gliosis, and status spongiosus. These findings are another distinctive MRI appearance in CJD.
Iwasaki
Y
Y
Fourth Department of Internal Medicine, Toho University, Ohashi Hospital, Tokyo, Japan.
Ikeda
K
K
Tagaya
N
N
Kinoshita
M
M
D000368:Aged; D001479:Basal Ganglia; D001921:Brain / Q000473:pathology*; D003342:Corpus Striatum / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D005917:Globus Pallidus / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013788:Thalamus / Q000473:pathology