Localization of the gene encoding a neutral amino acid transporter-like protein to human chromosome band 19q13.3 and characterization of a simple sequence repeat DNA polymorphism.
The gene encoding a human neutral amino acid transporter-like protein (SLC1A5) was mapped to chromosome band 19q13.3 by fluorescence in situ hybridization to metaphase chromosomes. A simple sequence repeat DNA polymorphism of the form (GT)n was identified in the 3'-untranslated region of SLC1A5 mRNA. Studies in the CEPH families showed significant evidence of linkage between this DNA polymorphism and markers localized to the distal long arm of chromosome 19.
Jones
E M
EM
Howard Hughes Medical Institute, University of Chicago, Illinois 60637.
Menzel
S
S
Espinosa
R
R
Le Beau
M M
MM
Bell
G I
GI
Takeda
J
J
D026905:Amino Acid Transport Systems; D000596:Amino Acids / Q000378:metabolism*; D001483:Base Sequence; D001693:Biological Transport, Active; D002352:Carrier Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19; D004247:DNA / Q000235:genetics; D017931:DNA Primers / Q000235:genetics; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid
D026905:Amino Acid Transport Systems; D000596:Amino Acids; D002352:Carrier Proteins; D017931:DNA Primers; D005819:Genetic Markers; D004247:DNA