Destructive synovitis in contralateral Perthes' disease. A report of 2 cases.
2 boys had unilateral Perthes' disease at the age of 5 years. After 6 and 7 years, respectively, both patients developed contralateral femoral head necrosis with rapid destruction leading to ankylosis of the hip. Histology of the synovium showed nonspecific synovitis. Both patients fulfilled criteria for oligo-articular juvenile chronic arthritis (JCA). The association with Perthes' disease suggests a common etiology.
Vanpaemel
L
L
Department of Pediatric Orthopedics, University Hospital for Children and Youth, Het Wilhelmina Kinderziekenhuis, Utrecht, The Netherlands.
Helders
P J
PJ
Kuis
W
W
Pruijs
H
H
Huber
J
J
Keessen
W
W
D000844:Ankylosis / Q000209:etiology; D001171:Arthritis, Juvenile / Q000209:etiology; D002675:Child, Preschool; D006621:Hip Joint / Q000473:pathology*; D006801:Humans; D007873:Legg-Calve-Perthes Disease / Q000150:complications* / Q000473:pathology; D008297:Male; D013585:Synovitis / Q000209:etiology* / Q000473:pathology