Differential sensitivity patterns in small cell lung cancer cell lines: detection and circumvention of resistance to topoisomerase II targeting drugs.
Jensen
P B
PB
Department of Oncology, Finsen Center, Rigshospitalet, Copenhagen.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000235:genetics; D004250:DNA Topoisomerases, Type II / Q000187:drug effects* / Q000378:metabolism; D004273:DNA, Neoplasm / Q000096:biosynthesis / Q000187:drug effects / Q000235:genetics; D004353:Drug Evaluation, Preclinical; D018432:Drug Resistance, Multiple; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000235:genetics; D010641:Phenotype; D011034:Podophyllotoxin / Q000494:pharmacology*; D014407:Tumor Cells, Cultured; D014410:Tumor Stem Cell Assay
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D004250:DNA Topoisomerases, Type II; D011034:Podophyllotoxin