[Evaluation of the potential of chemotherapy of glanders caused by Pseudomonas mallei strains resistant to sulfanilamides and trimethoprim].
A sulfanilamide resistant strain Ts-5 of Pseudomonas mallei was isolated in the experiments on sulfazine therapy of malleus. The spectrum and level of the strain cross resistance to sulfanilamides and trimethoprim were studied. The frequency of the SurTrr mutants of P. mallei was determined. Efficient antibacterial drugs for the therapy of malleus caused by the sulfanilamide resistant strain are recommended.
I N
IN
Manzeniuk
Iu G
IuG
Stepanshin
E A
EA
Svetoch
D000818:Animals; D006224:Cricetinae; D018432:Drug Resistance, Multiple / Q000502:physiology*; D005069:Evaluation Studies as Topic; D005896:Glanders / Q000188:drug therapy*; D008647:Mesocricetus; D011549:Pseudomonas / Q000187:drug effects*; D013424:Sulfanilamides / Q000627:therapeutic use*; D014296:Trimethoprim Resistance / Q000502:physiology*
D013424:Sulfanilamides
Otsenka vozmozhnosti khimioterapii sapa, vyzvannogo ustoĭchivymi k sul'fanilamidam i trimetoprimu shtammami Pseudomonas mallei.