[The prospects for using an indirect immunoenzyme method for the diagnosis of leptospirosis].
An evaluation was carried out of sensitivity and specificity of indirect enzyme immunoassay to be used for the identification of antileptospiral antibodies in the patients' sera. Ultrasonic antigenic preparations were used as an antigen. The test permits determining genus-specific antibodies as well as those of more restricted specificity including serogroup-specific ones. Time course of changes is presented of antibodies in different phases of the disease. In leptospiral patients the spectrum of the antibodies identified broadens with the use of polyvalent antigenic preparations.
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EV
D000907:Antibodies, Bacterial / Q000097:blood; D000918:Antibody Specificity; D005069:Evaluation Studies as Topic; D006801:Humans; D007124:Immunoenzyme Techniques; D007919:Leptospira / Q000145:classification / Q000276:immunology; D007922:Leptospirosis / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D012703:Serotyping; D013997:Time Factors
D000907:Antibodies, Bacterial
Perspektivy primeneniia nepriamogo immunofermentnogo metoda dlia diagnostiki leptospiroza.