A simple method of correlating pharmacodynamic equivalence with absolute bioavailability following noninvasive delivery of insulin.
Li
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Y
Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907-1336.
Mitra
A K
AK
D000818:Animals; D001682:Biological Availability; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D007262:Infusions, Intravenous; D007328:Insulin / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology; D007442:Intubation, Intratracheal; D007601:Jugular Veins; D008168:Lung / Q000378:metabolism; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013810:Therapeutic Equivalency
D001786:Blood Glucose; D007328:Insulin