Possible genes for left heart formation on 11q23.3.
A case of balanced translocation t (10; 11) (q 24; q 23) is presented. This female newborn showed no other malformation than hypoplastic left heart syndrome. According to several cases of 11q- and hypoplastic left heart in the literature and to this observation the authors postulate genes for left heart formation on chromosome 11q23.3.
University Children's Hospital Basel, Postfach, Switzerland.
J
J
Guenthard
E
E
Buehler
E
E
Jaeggi
F
F
Wyler
D000328:Adult; D002879:Chromosomes, Human, Pair 10; D002880:Chromosomes, Human, Pair 11; D005260:Female; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000235:genetics*; D007621:Karyotyping; D014178:Translocation, Genetic