Influenza hemagglutinin: kinetic control of protein function.
In response to decreased pH, influenza hemagglutinin changes to a more stable conformation. Such changes, which can be controlled thermodynamically or kinetically, are the method by which many biological 'switches' are thrown.
Baker
D
D
Department of Biochemistry, University of Washington, Seattle 98195.
Agard
D A
DA
D006389:Hemagglutinins, Viral / Q000737:chemistry / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008561:Membrane Fusion / Q000502:physiology; D015394:Molecular Structure; D009975:Orthomyxoviridae / Q000737:chemistry / Q000502:physiology*; D011487:Protein Conformation; D013816:Thermodynamics
D006389:Hemagglutinins, Viral