title: TAME-esterase activity during a prolonged attack of asthma.
abstract: We measured serum N-alpha-tosyl-L-arginine methyl ester (TAME)-esterase activity in a group of patients suffering from a prolonged attack of asthma. Measurements were made pre and post salbutamol nebulization. Our results showed that TAME-esterase activity did not change significantly pre or post nebulization. Based on our experimental data, we concluded that increase serum TAME-esterase activity is a biochemical substance associated with the early asthmatic response but not with prolonged attack of asthma.
authors.affiliation: Medical and Health Sciences Department, Faculty of Science, University of Mauritius, Réduit.
authors.forename: A H
authors.initials: AH
authors.lastname: Subratty
authors.forename: M Y
authors.initials: MY
authors.lastname: Yan
authors.forename: L H
authors.initials: LH
authors.lastname: Shun
authors.forename: A
authors.initials: A
authors.lastname: Hebe
authors.forename: V
authors.initials: V
authors.lastname: Soomaree
mesh_terms: D000328:Adult; D000420:Albuterol / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000201:enzymology*; D006801:Humans; D010447:Peptide Hydrolases / Q000097:blood* / Q000187:drug effects
chemical_list: D010447:Peptide Hydrolases; C023073:tosylarginine methyl ester hydrolase; D000420:Albuterol