title: [Danazol in the treatment of endometriosis].
abstract: 48 females with uterine endometriosis stage 1 and 2, 26 female with mild and moderate external endometriosis and 9 females with external in combination with internal endometriosis with the disease duration from 6 months to 10 years were given danazol in doses 200-400 mg/day for 6 months. The effect of the treatment proved to be very high: 37 patients were cured, 14 improved, 3 got pregnant. 11 patients needed the second treatment course. Side effects were rare. Depressed hyperactive menstrual cycle normalized quickly. It is inferred that danazol doses 200-400 mg/day are adequate for induction of complete or partial responses in internal and external endometriosis.
authors.forename: I S
authors.initials: IS
authors.lastname: Sidorov
authors.forename: T D
authors.initials: TD
authors.lastname: Guriev
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003613:Danazol / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D004715:Endometriosis / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D008875:Middle Aged; D014463:Ultrasonography; D014591:Uterine Diseases / Q000175:diagnosis / Q000188:drug therapy*; D014599:Uterus / Q000000981:diagnostic imaging
chemical_list: D003613:Danazol
vernacular_title: Danazol v lechenii éndometrioza.