[Myocardium protection using warm blood cardioplegia in corrective operation of tetralogy Fallot].
In this paper, the children, who had undergone the operation with the approach similar to that of Tetralogy Fallot, were selected and divided into 4 groups, according to different kinds of cardioplegia were infused during corrective operation. St. Thomas group (CC group) 24 cases, cold blood cardioplegia group (CBC group) 21 cases, terminal warm blood cardioplegia group (TWBC group) 12 cases, and continuous warm blood cardioplegia group (CWBC group) 12 cases. Through the measurement of left ventricular contraction pressure and CK-Mb release in the postoperative period, the effect of myocardial preservation was better in TWBC and CWBC groups than in CC and CBC groups (P < 0.05), ATP volume of myocardium in TWBC and CWBC groups were higher (17.1 and 18.2 mumol/g) than that in CBC group (2.48 mumol/g) (P < 0.01) CP values were respectively 8.74 mumol/g, 7.63 mumol/g and 5.5 mumol/g (P < 0.05). 9 cases (37%) in CC group needed inotropic drug to assist circulation postoperation, 4 cases (16%) in CBC group, 2 cases (12%) in both TWBC and CWBC group. The results demonstrated that WBC had a better myocardial protection effect.
Chen
R W
RW
General Hospital of Shenyang army of People's Liberation Army.
Wang
Z W
ZW
Xu
F X
FX
D001639:Bicarbonates / Q000627:therapeutic use; D001769:Blood; D002122:Calcium Chloride / Q000627:therapeutic use; D002314:Cardioplegic Solutions / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D006324:Heart Arrest, Induced; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use; D009206:Myocardium / Q000378:metabolism; D011189:Potassium Chloride / Q000627:therapeutic use; D012965:Sodium Chloride / Q000627:therapeutic use; D013771:Tetralogy of Fallot / Q000601:surgery*
D001639:Bicarbonates; D002314:Cardioplegic Solutions; C041711:St. Thomas' Hospital cardioplegic solution; D012965:Sodium Chloride; D011189:Potassium Chloride; D008274:Magnesium; D002122:Calcium Chloride