Blood viscosity and plasma viscosity in patients with sudden deafness.
Blood viscosity and plasma viscosity were measured in 51 patients with sudden deafness (SD) and 70 controls with normal hearing. Blood viscosity and plasma viscosity in patients with SD at their first medical examination were significantly higher than in the control group. The difference in viscosimetry results between the two groups was greater at higher shear rates. The data obtained in viscosimetry and pure-tone audiometry were analyzed after dividing the patients into a high viscosity group and a normal viscosity group. The correlation between average hearing level in pure-tone audiogram and blood viscosity or plasma viscosity was positive. The values of the O2-transport capacity of the blood demonstrated a negative correlation with average hearing level in patients with SD before treatment. During the course of treatment, blood viscosity and plasma viscosity decreased with the improvement of hearing impairment. When the distribution of average hearing level was 40 to 79 dB, a few of the patients with "recovery" or "good improvement" and most of patients with "fair improvement" or "no change" belonged to the low viscosity group. And, most of the patients with flat type hearing impairment and a few patients with high tone type hearing impairment belonged to the high viscosity group. These results suggest that many patients with SD have increased blood viscosity and plasma viscosity, and that this increase may play a significant role in the etiology of SD. There are also some differences in etiologic factors concerning type of hearing impairment and prognosis. In conclusion, the present study points to the importance of measuring blood viscosity and plasma viscosity in patients with SD, since blood and/or plasma viscosity may be involved in its etiology and prognosis.
Ohinata
Y
Y
Department of Otolaryngology, Saiseikai Nakatsu Hospital, Osaka, Japan.
Makimoto
K
K
Kawakami
M
M
Haginomori
S
S
Araki
M
M
Takahashi
H
H
D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D001809:Blood Viscosity; D015331:Cohort Studies; D007758:Ear, Inner / Q000098:blood supply / Q000503:physiopathology*; D005260:Female; D006309:Hearing / Q000502:physiology*; D003639:Hearing Loss, Sudden / Q000175:diagnosis / Q000503:physiopathology*; D006400:Hematocrit; D018056:Hemorheology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D011379:Prognosis