title: [Acquired heart diseases and pregnancy].
abstract: Understanding of the mechanisms of cardiovascular and hemodynamic adaptation during pregnancy helps to prevent or manage complications in cardiac patients during gestation. Manifestations of coronary heart disease are exceptional during pregnancy and delivery. The same is true of disorders of the pericardium. Peripartal cardiomyopathy is a myocardial disorder of undetermined cause occurring shortly before, during or after delivery, which may take a fatal course. Hypertrophic obstructive or non-obstructive cardiomyopathy is compatible with gestation and delivery without serious complications in most cases. Rheumatic mitral stenosis was the most common cardiac disorder until the 1950s. Nowadays it is rarely seen in this country. Surgical and other interventional therapies have greatly changed the outlook in pregnant women with valvular heart disease. A highly controversial issue is heart valve replacement in young women and management of anticoagulation during pregnancy. Like any other drug therapy, anticoagulation during gestation requires careful weighing of the benefit for the mother against toxic and teratogenic effects for the fetus. In women with heart disease the management of pregnancy should start, if possible, before conception. Thorough counseling and proper planning of pregnancy and of therapeutic measures is essential in order to avoid or manage complications.
authors.affiliation: Herzzentrum Hirslanden, Zürich.
authors.forename: M E
authors.initials: ME
authors.lastname: Rothlin
authors.forename: L
authors.initials: L
authors.lastname: Egloff
authors.forename: M
authors.initials: M
authors.lastname: Fleisch
authors.forename: H O
authors.initials: HO
authors.lastname: Hirzel
authors.forename: R
authors.initials: R
authors.lastname: Siebenmann
authors.forename: M
authors.initials: M
authors.lastname: Studer
authors.forename: R
authors.initials: R
authors.lastname: Tartini
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000503:physiopathology; D009202:Cardiomyopathies / Q000503:physiopathology; D002312:Cardiomyopathy, Hypertrophic / Q000503:physiopathology; D005260:Female; D006349:Heart Valve Diseases / Q000503:physiopathology / Q000601:surgery; D006439:Hemodynamics; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology* / Q000628:therapy; D011295:Prenatal Care; D011379:Prognosis
chemical_list: D000925:Anticoagulants
vernacular_title: Erworbene Herzkrankheiten und Schwangerschaft.