[The effect of coccidiostats on the growth capacity and the survival ability of Salmonella live vaccine agents].
Anticoccidial agents are obligatory feed additives during several rearing periods of poultry. The success of an oral immunization of young chicken with Salmonella live vaccines depends on the insensitivity of the vaccine strain against such anticoccidial agents because the vaccination success depends on the survival of the vaccine strain in the gut of the chick and the temporary colonization of lymphatic tissue. We investigated the in vitro sensitivity of the vaccine strain in the S. typhimurium live vaccine "Zoosaloral H" registered for the vaccination of poultry in Germany in connection with often used anticoccidial agents (Diclazuril, Monensin, Narasin and Salinomycin). No differences in growth and survival between the samples containing and lacking anticoccidial agents were found even by using double amounts of the permitted concentration of the anticoccidial agents. No negative effects of the tested anticoccidial agents on Salmonella being used as oral live vaccines in poultry should be expected.
Martin
G
G
Institut für Veterinärmedizin (Robert von Ostertag-Institut), Bereich Jena.
Meyer
H
H
D000818:Animals; D001428:Bacterial Vaccines; D002645:Chickens; D003049:Coccidiostats / Q000494:pharmacology*; D011201:Poultry Diseases / Q000517:prevention & control*; D012475:Salmonella / Q000187:drug effects* / Q000254:growth & development; D012481:Salmonella Infections, Animal / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary
D001428:Bacterial Vaccines; D003049:Coccidiostats
Einfluss von Kokzidiostatika auf das Wachstumsvermögen und die Uberlebensfähigkeit von Salmonella-Lebendimpfstoff-Keimen.