title: The perspective of patients with vascular disease on participation in clinical trials.
abstract: Very little objective data are available concerning the patient's perspective on clinical trial participation. Participants from the Asymptomatic Carotid Atherosclerosis Study and Clopidogrel vs. Aspirin in Patients at Risk for Ischemic Events Trial were personally interviewed by the nurse coordinator to document their views. A questionnaire including both closed-ended and open-ended questions was used. The main advantages to participation in a study were close follow-up and the opportunity for improved health. More than half of the subjects saw no disadvantages to participation. The physician was the primary motivator for entering trials. Most patients expressed an interest in future study participation.
authors.forename: M
authors.initials: M
authors.lastname: Wilcox
authors.forename: S
authors.initials: S
authors.lastname: Schroer
mesh_terms: D000328:Adult; D000368:Aged; D001294:Attitude to Health; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000523:psychology*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires