title: Inhaled nitric oxide for premature infants after prolonged rupture of the membranes.
abstract: We evaluated the use of inhaled nitric oxide in eight premature infants (520 to 1440 gm, 24 to 31 weeks of gestation) who failed to respond to conventional management and who had prolonged rupture of the membranes and oligohydramnios. All infants had a significant improvement in oxygenation and a fall in mean airway pressure with inhaled nitric oxide. Further studies are required to determine the safety and efficacy of this form of therapy.
authors.affiliation: Department of Newborn Medicine, Royal Alexandra Hospital, University of Alberta, Edmonton, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Peliowski
authors.forename: N N
authors.initials: NN
authors.lastname: Finer
authors.forename: P C
authors.initials: PC
authors.lastname: Etches
authors.forename: A J
authors.initials: AJ
authors.lastname: Tierney
authors.forename: C A
authors.initials: CA
authors.lastname: Ryan
mesh_terms: D000280:Administration, Inhalation; D005069:Evaluation Studies as Topic; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000150:complications; D006801:Humans; D000860:Hypoxia / Q000628:therapy*; D007231:Infant, Newborn; D007234:Infant, Premature; D009569:Nitric Oxide / Q000627:therapeutic use*; D016104:Oligohydramnios / Q000150:complications; D010102:Oxygen Inhalation Therapy; D011247:Pregnancy; D016896:Treatment Outcome
chemical_list: D009569:Nitric Oxide