title: Calculation of dose, dose equivalent, and relative biological effectiveness for high charge and energy ion beams.
abstract: The Green's function for the transport of ions of high charge and energy is utilized with a nuclear fragmentation database to evaluate dose, dose equivalent, and RBE for C3H10T1/2 cell survival and neoplastic transformation as a function of depth in soft tissue. Such evaluations are useful to estimates of biological risk for high altitude aircraft, space operations, accelerator operations, and biomedical applications.
authors.affiliation: NASA Langley Research Center, Hampton, VA 23681-0001.
authors.forename: J W
authors.initials: JW
authors.lastname: Wilson
authors.forename: M
authors.initials: M
authors.lastname: Reginatto
authors.forename: F
authors.initials: F
authors.lastname: Hajnal
authors.forename: S Y
authors.initials: SY
authors.lastname: Chun
mesh_terms: D000401:Aircraft; D000531:Altitude; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects*; D002471:Cell Transformation, Neoplastic; D004307:Dose-Response Relationship, Radiation; D051379:Mice; D008809:Mice, Inbred C3H; D008962:Models, Theoretical; D009683:Nuclear Medicine; D010315:Particle Accelerators; D013026:Space Flight