title: [Cerebral metastases of testicular neoplasms. Apropos of 2 cases and review of the literature].
abstract: The authors report two cases of brain metastasis of a testicular cancer in two young men. In the first case the histology was an embryonal carcinoma, in the second the association of a seminoma and a teratocarcinoma. The first patient was submitted to chemotherapy, neurosurgery and radiotherapy. The second one to chemotherapy alone. The survival time was respectively of 16 and 58 months. It looked interesting to review the different treatments and their indications in this extremely severe pathology to define the interest of surgery and radiotherapy, and the different prognostic factors. In the literature, among the various treatment, the role of chemotherapy is widely emphasized. The prognosis remains desperately bad when several brain metastasis exist, or if a brain metastasis develops during chemotherapy.
authors.affiliation: Service de Neurochirurgie, CHRU de Poitiers.
authors.forename: M
authors.initials: M
authors.lastname: Guenot
authors.forename: M
authors.initials: M
authors.lastname: Wager
authors.forename: B
authors.initials: B
authors.lastname: Bataille
authors.forename: J
authors.initials: J
authors.lastname: Irani
authors.forename: F
authors.initials: F
authors.lastname: Lapierre
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy
vernacular_title: Métastases cérébrales des cancers testiculaires. A propos de deux cas et revue de la littérature.