[Change in functional and metabolic activity of leukocytes and content of serum immunoglobulins of donor blood exposed to gamma radiation].
Changes in functional-metabolic activity of leukocytes and in donor serum immunoglobulin level in exposure to gamma radiation. B.S. Nagoev. Kabardin-Balkar University, Nalchik. The study of 40 samples of blood after 1-4 days of storage revealed a moderate significant reduction in concentrations of cation protein, in myeloperoxidase activity. In exposure to gamma radiation, there appeared dose- and intensity-related shifts in the blood elements morphology, inhibition of myeloperoxidase, in the content of leukocyte cation protein, serum immunoglobulins. These alterations in white blood morphological picture, inhibition of functional-metabolic activity of leukocytes and immunoglobulin unbalance during gamma radiation of isolated blood explain depression of immunobiological characteristics of the body in extreme conditions, particularly, the lack of antibacterial defense as a result of ionizing radiation.
Nagoev
B S
BS
D000328:Adult; D001782:Blood Donors; D005260:Female; D005720:Gamma Rays; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism*; D007962:Leukocytes / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged
D007136:Immunoglobulins
Izmenenie funktsional'no-metabolicheskoĭ aktivnosti leĭkotsitov i soderzhaniia immunoglobulinov syvorotki donorskoĭ krovi pod vliianiem oblucheniia gamma-luchami.