Distribution of the CorA Mg2+ transport system in gram-negative bacteria.
The CorA Mg2+ transport system is the dominant constitutive uptake mechanism in Salmonella typhimurium and Escherichia coli. Southern blot hybridization and PCR techniques were used to screen a panel of 18 additional gram-negative bacterial species for corA homologs. Virtually all strains tested positive for the presence of corA. Thus, corA appears to be ubiquitous within gram-negative bacteria and is likely their major Mg2+ influx system.
Smith
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Department of Pharmacology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106-4965.
Maguire
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ME
D001426:Bacterial Proteins / Q000235:genetics*; D001692:Biological Transport / Q000235:genetics; D015139:Blotting, Southern; D002352:Carrier Proteins / Q000235:genetics*; D027682:Cation Transport Proteins; D017931:DNA Primers; D006090:Gram-Negative Bacteria / Q000145:classification / Q000235:genetics*; D008274:Magnesium / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D013045:Species Specificity
D001426:Bacterial Proteins; D002352:Carrier Proteins; D027682:Cation Transport Proteins; C072716:CorA protein, Salmonella; D017931:DNA Primers; D008274:Magnesium