Organic mood disorder, manic type, associated with hyponatremia: a case report.
OBJECTIVE
Mania and other mood changes are known to be associated with various organic etiologies. This article documents a case of organic mania associated with hyponatremia, a phenomenon which has not been previously reported, and reviews the pertinent medical literature.


METHODS
The mental status of a patient with end stage renal disease and no previous psychiatric history who presented with mania and hyponatremia was carefully monitored while her serum sodium concentration was corrected.


RESULTS
The manic symptoms of the patient presented resolved completely with correction of serum sodium concentration alone.


CONCLUSIONS
The acute episode of hyponatremia experienced by this patient with chronic, end stage renal disease appears to have precipitated the symptoms of mania. This observation may shed some additional light on the pathophysiology of organic mania.
Baar
J M
JM
Baylor College of Medicine Affiliated Hospital, Houston, Texas.
D000328:Adult; D001714:Bipolar Disorder / Q000097:blood / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000097:blood / Q000175:diagnosis* / Q000523:psychology; D007676:Kidney Failure, Chronic / Q000097:blood / Q000175:diagnosis / Q000523:psychology; D007677:Kidney Function Tests; D008609:Mental Status Schedule; D019965:Neurocognitive Disorders / Q000097:blood / Q000175:diagnosis* / Q000523:psychology; D009483:Neuropsychological Tests; D010348:Patient Care Team; D012964:Sodium / Q000097:blood
D012964:Sodium