o-, m- and p-hydroxybenzoate degradative pathways in Rhodococcus erythropolis.
Rhodococcus erythropolis strain S1 uses the gentisate pathway to metabolize salicylate and m-hydroxybenzoate and the protocatechuate pathway to degrade p-hydroxybenzoate. m-Hydroxybenzoate 6-hydroxylase was induced by growth on m-hydroxybenzoate or gentisate, and salicylate 5-hydroxylase only by growth on salicylate. p-Hydroxybenzoate 3-hydroxylase could be induced only by growth on p-hydroxybenzoate. m-Hydroxybenzoate or p-hydroxybenzoate could repress the induction of salicylate 5-hydroxylase. Maleylpyruvate isomerase in the gentisate pathway did not require reduced glutathione.
Suemori
A
A
National Institute of Bioscience and Human-Technology (NIBH), Ibaraki, Japan.
Nakajima
K
K
Kurane
R
R
Nakamura
Y
Y
D005841:Gentisates; D005978:Glutathione / Q000378:metabolism; D062385:Hydroxybenzoates / Q000378:metabolism*; D007535:Isomerases / Q000378:metabolism; D007700:Kinetics; D006899:Mixed Function Oxygenases / Q000378:metabolism; D010101:Oxygen Consumption; D010226:Parabens / Q000378:metabolism*; D012240:Rhodococcus / Q000254:growth & development / Q000378:metabolism*; D012459:Salicylates / Q000378:metabolism*; D020156:Salicylic Acid; D019745:cis-trans-Isomerases
D005841:Gentisates; D062385:Hydroxybenzoates; D010226:Parabens; D012459:Salicylates; C032948:3-hydroxybenzoic acid; C009091:protocatechuic acid; D006899:Mixed Function Oxygenases; C022619:salicylate 1-monooxygenase; D007535:Isomerases; D019745:cis-trans-Isomerases; C046138:maleylpyruvate isomerase; D005978:Glutathione; C038193:4-hydroxybenzoic acid; D020156:Salicylic Acid; C010925:2,5-dihydroxybenzoic acid