Some general aspects of immunity to viruses.
Immunity to viruses reveals strength and limiting aspects of both. The role of viral antigen distribution and persistence in inducing T cell responses, in escaping from them or inducing and exhausting them in cytopathic viruses is compared with that for non-cytopathic viruses. Accordingly, vaccination may be protectively efficient, or not, and can shift the relative kinetics beneficially or, in rare cases, also in a harmful way.
Zinkernagel
R M
RM
Institute of Experimental Immunology, University Hospital Zurich, Switzerland.
D000818:Animals; D000917:Antibody Formation / Q000276:immunology*; D000956:Antigens, Viral / Q000276:immunology*; D007111:Immunity, Cellular / Q000276:immunology*; D014765:Viral Vaccines / Q000009:adverse effects / Q000276:immunology
D000956:Antigens, Viral; D014765:Viral Vaccines