Chromatographic analysis (TLC) aprindine and nadoxolol in human plasma.
Aprindine and nadoxolol extracted from plasma were separated by TLC method on silica gel by ascending technique on 5 x 20 cm and 2.5 x 7.5 cm microscopic slides and also by horizontal development, using suitable mobile phases. The substances were identified by reaction with Kiefer reagent (up to the amount 100 ng of aprindine and 300 ng of nadoxolol).
Misztal
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G
Department of Medicinal Chemistry, School of Medicine, Lublin, Poland.
Gumieniczek
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A
D000889:Anti-Arrhythmia Agents / Q000097:blood*; D001073:Aprindine / Q000097:blood*; D002855:Chromatography, Thin Layer; D006801:Humans; D010091:Oximes / Q000097:blood*
D000889:Anti-Arrhythmia Agents; D010091:Oximes; D001073:Aprindine; C006154:nadoxolol