title: [The A-form of DNA: in search of the biological role].
abstract: Only recently first direct evidence for the involvement of the A-DNA in the biological processes and structures has been obtained. This was preceded by numerous studies during four decades, which revealed structural features of this second, next to the B-form, DNA conformation, the conditions for the B to A transition to occur in a tube, the requirements to nucleotide sequence. Due to these works the B-A cooperative transition in DNA is now understood as good as the DNA melting. The above physico-chemical studies forced one to think on the "biology" of the A-conformation and at the same time provided experimental possibilities for finding it in biological processes.
authors.forename: V I
authors.initials: VI
authors.lastname: Ivanov
authors.forename: L E
authors.initials: LE
authors.lastname: Minchenkova
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000502:physiology; D008024:Ligands; D008962:Models, Theoretical; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012996:Solutions; D014158:Transcription, Genetic
chemical_list: D008024:Ligands; D012996:Solutions; D004247:DNA
vernacular_title: A-forma DNK: v poiskakh biologicheskoĭ roli.