title: [10-year follow-up after surgery for colon cancer: no further mortality from cancer after 7 years].
abstract: OBJECTIVE
  To evaluate the 10-year follow-up of a cohort of 141 patients operated between 1979 and 1981, and to analyse the prognostic significance of traditional tumour parameters, using a univariate and a multivariate analysis.
  
  
  METHODS
  Prospective descriptive study.
  
  
  METHODS
  Department of Surgery, University Hospital Maastricht, the Netherlands.
  
  
  METHODS
  In 1979 a database was established in which 141 consecutive patients with colorectal carcinoma were included. The 5-year and 10-year survival rates were determined and the values of the clinicopathological staging (deducted from the Dukes classification), CEA expression, tumour size, localisation of the tumour and age of the patient as tumour markers were assessed.
  
  
  RESULTS
  The 5-year and 10-year survival rates were 30.5% and 15.6% respectively. The Dukes staging system appeared to be the most important prognostic factor for survival (p = 0.0004), but tumour size and shape, and central lymph node involvement were independent prognostic factors. Furthermore, no patients died as a result of colon tumour after 7 years of follow-up.
  
  
  CONCLUSIONS
  The Dukes staging system is the most important prognostic factor for survival. The follow-up of patients treated for colon carcinoma can be stopped after seven years. Only polyp surveillance should be continued after this time.
authors.affiliation: Afd. Heelkunde, Academisch Ziekenhuis, Maastricht.
authors.forename: B
authors.initials: B
authors.lastname: Gerdts
authors.forename: M F
authors.initials: MF
authors.lastname: von Meyenfeldt
authors.forename: J
authors.initials: J
authors.lastname: Meijerink
authors.forename: A P
authors.initials: AP
authors.lastname: de Bruïne
authors.forename: J W
authors.initials: JW
authors.lastname: Arends
authors.forename: T
authors.initials: T
authors.lastname: Wiggers
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000302:isolation & purification; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D012044:Regression Analysis; D015996:Survival Rate
chemical_list: D002272:Carcinoembryonic Antigen
vernacular_title: Tien jaar follow-up na operatie wegens colonkanker: na 7 jaar geen sterfte meer door de kanker.