[Computer technology for genetic-geographical study of the gene pool. II. Statistical transformation of maps].
Transformations of computer maps of geographical distribution of gene frequencies using basic mathematical statistical procedures are considered. These transformations are designated as statistical transformation of maps. Two transformation groups are considered: of one map separately and of a group of maps. Transformations possess a value beyond their use as intermediate stages of more complicated cartographical analysis: the resulting maps carry entirely new information on the geography of genes or a gene pool. This article considers three examples of obtaining new genetic profiles using statistical transformation algorithms. These profiles are of: heterozygosity (of HLA-A, B, C loci in northeastern Eurasia); (2) disease risk (Rh-incompatibility of mother and child with simultaneous registration of Rh and ABO blood groups in Eastern Europe); (3) genetic distances (from own mean ethnic values for Belarus' and from mean Russian values for the gene pool of Eastern Europe).
Balanovskaia
E V
EV
Nurbaev
S D
SD
Rychkov
Iu G
IuG
D000017:ABO Blood-Group System / Q000235:genetics; D000465:Algorithms; D005787:Gene Frequency; D005788:Gene Pool; D005843:Geography; D006680:HLA Antigens / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D015233:Models, Statistical; D012204:Rh-Hr Blood-Group System / Q000235:genetics; D012426:Russia
D000017:ABO Blood-Group System; D006680:HLA Antigens; D012204:Rh-Hr Blood-Group System
Komp'iuternaia tekhnologiia genogeograficheskogo izucheniia genofonda. II. Statiticheskaia transformatsiia kart.