title: A comparison between the hemolytic and antibacterial activities of new quaternary ammonium polymers.
abstract: New quaternary ammonium polymers, which in a previous work had shown relevant antibacterial properties, have been investigated as regards to their hemolytic activity (HA) in comparison with a low molecular weight commercial antibacterial agent, Steramine G (SG). All polymers exhibit negligible, or at most modest, HA at dosages and contact times at which SG is strongly hemolytic.
authors.affiliation: Istituto di Chirurgia Generale e Cardiovascolare, Milano, Italy.
authors.forename: M A
authors.initials: MA
authors.lastname: Marchisio
authors.forename: P
authors.initials: P
authors.lastname: Bianciardi
authors.forename: T
authors.initials: T
authors.lastname: Longo
authors.forename: P
authors.initials: P
authors.lastname: Ferruti
authors.forename: E
authors.initials: E
authors.lastname: Ranucci
authors.forename: M G
authors.initials: MG
authors.lastname: Neri
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects*; D015394:Molecular Structure; D011108:Polymers / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D000644:Quaternary Ammonium Compounds; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D011108:Polymers; D000644:Quaternary Ammonium Compounds