title: Mycobacterium genavense infection presenting as a solitary brain mass in a patient with AIDS: case report and review.
abstract: Patients with AIDS are prone to developing infections with opportunistic pathogens. Recently, a new mycobacterium, Mycobacterium genavense, has been found to cause infection in patients with AIDS. Previously published reports indicate that patients who are infected with this organism present with the same clinical features as do patients with disseminated infection due to organisms of the Mycobacterium avium complex. We describe an unusual case of a patient with AIDS who presented with grand mal seizures and a mass lesion in his brain, which was found to be caused by infection with M. genavense. No evidence of disseminated infection could be found in this patient. We discuss the microbiology of this organism and review the literature on M. genavense infections. Clinicians should be aware of this organism so that efforts at culture and identification will be made.
authors.affiliation: Department of Medicine, Veterans Affairs Medical Center, Long Beach, California.
authors.forename: S M
authors.initials: SM
authors.lastname: Berman
authors.forename: R C
authors.initials: RC
authors.lastname: Kim
authors.forename: D
authors.initials: D
authors.lastname: Haghighat
authors.forename: M E
authors.initials: ME
authors.lastname: Mulligan
authors.forename: J
authors.initials: J
authors.lastname: Fierer
authors.forename: F C
authors.initials: FC
authors.lastname: Wyle
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D000900:Anti-Bacterial Agents; D001921:Brain / Q000187:drug effects / Q000382:microbiology / Q000473:pathology*; D001927:Brain Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents