title: Diffuse plane xanthomatosis and acquired palmoplantar keratoderma in association with myeloma.
abstract: We report a patient with diffuse plane xanthomatosis, acquired palmoplantar keratoderma, and myeloma. Although diffuse plane xanthomatosis is a recognized manifestation of paraproteinaemia, keratoderma is not. However, successful treatment of the myeloma in our patient coincided with a dramatic improvement in the keratoderma, suggesting a genuine association between the two disorders.
authors.affiliation: St John's Insititute of Dermatology UMDS, London, U.K.
authors.forename: C H
authors.initials: CH
authors.lastname: Smith
authors.forename: J N
authors.initials: JN
authors.lastname: Barker
authors.forename: R J
authors.initials: RJ
authors.lastname: Hay
mesh_terms: D000368:Aged; D006801:Humans; D015776:Keratoderma, Palmoplantar, Diffuse / Q000150:complications*; D008297:Male; D008558:Melphalan / Q000627:therapeutic use; D009101:Multiple Myeloma / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D014973:Xanthomatosis / Q000150:complications* / Q000473:pathology
chemical_list: D011239:Prednisolone; D008558:Melphalan