title: [Hyperthyroidism and hypersecretion of chorionic gonadotropin in gastric adenocarcinoma].
abstract: We report a case of hyperthyroidism complicating and revealing a metastatized adenocarcinoma of the stomach with high circulating levels of human chorionic gonadotropin and its beta component. To our knowledge, this is the first reported case of a non-trophoblastic tumor with hyperthyroidism and secreting quantities of these hormones. High circulating levels of beta component in such patients have been considered to be a sign of malignancy. The mechanisms of thyroid stimulation could be related to the biological activity of certain forms of the human chorionic gonadotropin.
authors.affiliation: Service de médecine interne, CMC Foch, Suresnes, France.
authors.forename: C
authors.initials: C
authors.lastname: Brousse
authors.forename: L
authors.initials: L
authors.lastname: Mignot
authors.forename: A C
authors.initials: AC
authors.lastname: Baglin
authors.forename: N
authors.initials: N
authors.lastname: Bernard
authors.forename: A M
authors.initials: AM
authors.lastname: Piette
authors.forename: P
authors.initials: P
authors.lastname: Gepner
authors.forename: A
authors.initials: A
authors.lastname: Chapman
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000378:metabolism*; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000150:complications / Q000378:metabolism*
chemical_list: D006063:Chorionic Gonadotropin
vernacular_title: Hyperthyroïdie et hypersécrétion de gonadotrophine chorionique au cours d'un adénocarcinome gastrique.