[Bile duct carcinoma after abdominal irradiation for urologic malignancies].
Malignancies of the biliary tract are rare diseases. Tumor inductions after radiotherapy are reported in several papers. We report about 3 cases with consecutive biliary tract carcinoma 18-32 years after manifestation of an urogenital carcinoma. All 3 patients (52-63 years) were treated with additive radiotherapy after surgical-urological therapy. Icterus was the top-ranging symptom of this secondary carcinoma. In 2 of the 3 cases surgical tumor resection was performed (biliary duct resection with central liver resection; pancreatico-duodenectomy). Because of the bad general condition of health the third patient got only a biopsy of the tumor. All patients died within 2 years after diagnosis. The accidental accumulation of the rare biliary tract carcinoma after urogenital malignancies in our collection of clinical cases (2 seminoma; 1 bladder tumor) give rise the question about the causal association between primary carcinoma, additive therapy and the development of secondary carcinoma.
Biermann
C W
CW
Abteilung für Allgemeinchirurgie, Universitätskrankenhaus Eppendorf, Hamburg.
Fröschle
G
G
Kuhlencordt
R
R
Schwarz
R
R
Gonnermann
D
D
D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D002288:Adenocarcinoma, Mucinous / Q000473:pathology / Q000601:surgery; D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology / Q000601:surgery*; D003131:Combined Modality Therapy; D003138:Common Bile Duct Neoplasms / Q000473:pathology / Q000601:surgery; D015653:Cystectomy; D006500:Hepatic Duct, Common / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000601:surgery*; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000601:surgery*; D009919:Orchiectomy; D016577:Pancreaticoduodenectomy; D018714:Radiotherapy, Adjuvant; D012086:Reoperation; D018239:Seminoma / Q000532:radiotherapy* / Q000601:surgery; D013736:Testicular Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000532:radiotherapy* / Q000601:surgery
Gallengangkarzinome nach abdomineller Bestrahlung urologischer Malignome.