title: [Human lung connective tissue in postnatal ontogeny].
abstract: Changes of the connective tissue structures, appearing during all postnatal ontogenesis stages were studied in 147 human lung specimens of different age groups (from newborns up to 82-year-olds). Qualitative and quantitative composition of connective tissue structures changes with the age which leads to the lateral aggregation of the fibers and growth of the general mass of the connective tissue. Heterochronia of the age variability manifestations in different regions of the lung framework was demonstrated. The original age transformations of connective tissue structures are characteristic for the basal lung regions. With the exception of perivasal connective tissue, similar changes in the region of the lung apexes appear 3-5 years later. This gives an opportunity to distinguish three anatomic zones in the lungs in an apico-basal direction, characterising the local nature of the age changes manifestations.
authors.forename: A A
authors.initials: AA
authors.lastname: Kasimtsev
authors.forename: V G
authors.initials: VG
authors.lastname: Nikolaev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D002648:Child; D002675:Child, Preschool; D003238:Connective Tissue / Q000201:enzymology / Q000254:growth & development* / Q000648:ultrastructure; D006651:Histocytochemistry; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000201:enzymology / Q000254:growth & development* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged
vernacular_title: Soedinitel'naia tkan' legkikh cheloveka v postnatal'nom ontogeneze.