[Neuroleptic catalepsy in rats is accompanied by activation of brain prolyl endopeptidase and is eliminated by inhibitors of this enzyme].
Narkevich
V B
VB
Nazarova
G A
GA
Zolotov
N N
NN
Pozdnev
V F
VF
Raevskiĭ
K S
KS
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D002375:Catalepsy / Q000139:chemically induced / Q000188:drug therapy*; D004789:Enzyme Activation; D006220:Haloperidol / Q000009:adverse effects*; D007930:Leucine / Q000031:analogs & derivatives / Q000627:therapeutic use; D000085822:Prolyl Oligopeptidases; D051381:Rats; D012697:Serine Endopeptidases / Q000378:metabolism*; D015842:Serine Proteinase Inhibitors / Q000627:therapeutic use*; D015244:Thiorphan / Q000627:therapeutic use; D014268:Trifluoperazine / Q000009:adverse effects*
D015842:Serine Proteinase Inhibitors; D014268:Trifluoperazine; D015244:Thiorphan; D012697:Serine Endopeptidases; D000085822:Prolyl Oligopeptidases; D007930:Leucine; C012211:ubenimex; D006220:Haloperidol
Neĭrolepticheskaia katalepsiia u krys soprovozhdaetsia aktivatsieĭ proliléndopeptidazy mozga i ustraniaetsia ingibitorami étogo fermenta.