title: [Models of the organization of neonatal screening].
abstract: The authors evaluate the different organizational strategies of a congenital hypothyroidism screening program. Positive and negative aspects of laboratory screening tests (TSH only, T4-supplemental TSH, TSH and T4), organization strategies (centralization or decentralization), recall and first follow-up criteria are examined. The authors consider that the necessity for an early diagnostic confirmation can be associated with a precise etiologic diagnosis and an evaluation of the prenatal severity of congenital hypothyroidism factors. Some European and North-American experiences are compared with the activity of a regional Italian screening center.
authors.affiliation: I Clinica Pediatrica, Università degli Studi, Bologna.
authors.forename: A
authors.initials: A
authors.lastname: Cassio
authors.forename: S
authors.initials: S
authors.lastname: Piazzi
authors.forename: C
authors.initials: C
authors.lastname: Colli
authors.forename: A
authors.initials: A
authors.lastname: Balsamo
authors.forename: D
authors.initials: D
authors.lastname: Bozza
authors.forename: S
authors.initials: S
authors.lastname: Salardi
authors.forename: G
authors.initials: G
authors.lastname: Sprovieri
authors.forename: E
authors.initials: E
authors.lastname: Cacciari
mesh_terms: D003409:Congenital Hypothyroidism; D005188:False Negative Reactions; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000517:prevention & control; D007231:Infant, Newborn; D007558:Italy; D017146:Models, Organizational; D015997:Neonatal Screening / Q000458:organization & administration*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Modelli di organizzazione degli screening neonatali.