title: Technetium Tc 99m sestamibi scan for localizing abnormal parathyroid glands after previous neck operations: preliminary experience in reoperative cases.
abstract: We used technetium Tc 99m sestamibi for successful preoperative localization of abnormal parathyroid glands in nine patients with hyperparathyroidism and a history of neck surgery. The intraoperative and pathological findings were correlated with the preoperative technetium-sestamibi scan results. These nine patients had had 13 previous neck operations, two for thyroid disease, and 11 for hyperparathyroidism. In the two operated on for thyroid disease, the 99mTc-sestamibi scan localized a parathyroid adenoma. In one patient, the three remaining hyperplastic parathyroid glands were localized using 99mTc-sestamibi scan. The other six patients had 10 operations for hyperparathyroidism; the 99mTc-sestamibi scan localized the remaining parathyroid glands causing hypercalcemia. In this preliminary experience, the 99mTc-sestamibi scan localized all the abnormal parathyroid glands causing hyperparathyroidism in patients who had previously had neck surgery.
authors.affiliation: Department of Endocrine Surgery, Medical College of Georgia, Augusta 30912-4000.
authors.forename: J D
authors.initials: JD
authors.lastname: Majors
authors.forename: G J
authors.initials: GJ
authors.lastname: Burke
authors.forename: A R
authors.initials: AR
authors.lastname: Mansberger
authors.forename: J P
authors.initials: JP
authors.lastname: Wei
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging* / Q000601:surgery; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000000981:diagnostic imaging / Q000473:pathology*; D011300:Preoperative Care; D011446:Prospective Studies; D011877:Radionuclide Imaging; D012086:Reoperation; D017256:Technetium Tc 99m Sestamibi
chemical_list: D017256:Technetium Tc 99m Sestamibi