Dermatomyositis associated with malignant melanoma--case report and review of the literature.
Dermatomyositis (DM) is a connective tissue disorder characterized by cutaneous and muscle involvement. It is a well recognized paraneoplastic syndrome and has been linked with malignancy in 15-34% of adult patients. The course of DM in such patients usually correlates closely with the activity of the underlying malignancy. We report a patient who developed DM 4 years after excision of a malignant melanoma (MM) from the back and 1 year before the diagnosis of metastatic disease. A literature review revealed that the association of dermatomyositis with MM is rare and consistent with a dismal prognosis.
Scerri
L
L
Department of Dermatology, University Hospital, Queen's Medical Centre, Nottingham, UK.
Zaki
I
I
Allen
B R
BR
Golding
P
P
D003882:Dermatomyositis / Q000150:complications*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D011379:Prognosis; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology