title: Travelling waves in a tissue interaction model for skin pattern formation.
abstract: Tissue interaction plays a major role in many morphogenetic processes, particularly those associated with skin organ primordia. We examine travelling wave solutions in a tissue interaction model for skin pattern formation which is firmly based on the known biology. From a phase space analysis we conjecture the existence of travelling waves with specific wave speeds. Subsequently, analytical approximations to the wave profiles are derived using perturbation methods. We then show numerically that such travelling wave solutions do exist and that they are in good agreement with out analytical results. Finally, the biological implications of our analysis are discussed.
authors.affiliation: Department of Applied Mathematics, University of Washington, Seattle 98195.
authors.forename: G C
authors.initials: GC
authors.lastname: Cruywagen
authors.forename: P K
authors.initials: PK
authors.lastname: Maini
authors.forename: J D
authors.initials: JD
authors.lastname: Murray
mesh_terms: D000818:Animals; D003198:Computer Simulation; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology; D008954:Models, Biological; D008962:Models, Theoretical; D012867:Skin / Q000166:cytology; D012879:Skin Physiological Phenomena; D012984:Software