Multifocal inflammatory leukoencephalopathy developing in a patient receiving 5-fluorouracil and levamisole.
A single case of multifocal inflammatory leukoencephalopathy, which developed during a course of adjuvant chemotherapy with 5-fluorouracil (5FU) and levamisole is reported. Clinical features developed slowly and were not dramatic; this condition may therefore frequently be missed.
Critchley
P
P
Department of Neurology, Leicester Royal Infirmary NHS Trust, UK.
Abbott
R
R
Madden
F J
FJ
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001921:Brain / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000601:surgery; D003711:Demyelinating Diseases / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects; D006801:Humans; D007978:Levamisole / Q000009:adverse effects; D008279:Magnetic Resonance Imaging
D007978:Levamisole; D005472:Fluorouracil