[Familial aggregation of lung cancer in families of patients with lung cancer].
For determination of whether lung cancer clusters in families, an analysis was conducted on morbidity-mortality data, occupational and tobacco use practices for family members of 189 lung cancer probands and 211 controls (patients without cancer admitted to hospital because of accidents). Significant increase (1.48) was observed in cancers of all anatomic sites among relatives of lung cancer patients. Overall male relatives of lung cancer patients had 9.5 and female 11.8 greater risk for lung cancer than relatives of controls. This results remained significant after adjusting for age and smoking.
Radzikowska
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III Kliniki Gruźlicy i Chorób Płuc Instytutu Gruźlicy i Chorób Płuc w Warszawie.
Rowińska-Zakrzewska
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D000230:Adenocarcinoma / Q000235:genetics; D000328:Adult; D000368:Aged; D018288:Carcinoma, Small Cell / Q000235:genetics; D002294:Carcinoma, Squamous Cell / Q000235:genetics; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
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