Soluble interleukin-2 receptor in serum of patients with esophageal carcinoma.
We measured serum levels of sIL-2R in 28 patients with squamous cell esophageal carcinoma and in 12 controls. Sera for presence of sIL-2R were examined using DAKO Interleukin-2-receptor (CD25) ELISA. The samples were analyzed for CEA and SCC by using IMx System (Abbot). The mean values of sIL-2R in esophageal carcinoma group were significantly increased in comparison with control group. Our results suggest that sIL-2R may be useful in monitoring and prognosis estimation of disease in esophageal carcinoma and could be a valuable addition to the current spectrum of cancer markers.
Jabłońska
E
E
Department of Immunopathology, Medical Academy, Białystok, Poland.
Kozłowski
M
M
Pietruska
Z
Z
Furman
M
M
D000328:Adult; D000368:Aged; D002272:Carcinoembryonic Antigen / Q000097:blood; D002294:Carcinoma, Squamous Cell / Q000097:blood* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D004938:Esophageal Neoplasms / Q000097:blood* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000378:metabolism*
D002272:Carcinoembryonic Antigen; D015375:Receptors, Interleukin-2