title: Primary squamous cell carcinoma of the endometrium: a case report and a suggestion of new histogenesis.
abstract: A case of primary endometrial squamous cell carcinoma (ESCC) in a 75-year-old woman is reported. In her endometrium, mature stratified squamous epithelium was associated with mucinous glands in which epithelium and glands were identical to those of the uterine cervix, but which were not connected with the cervix. Thus, the endometrial squamous epithelium with mucinous glands was diagnosed as heterotopic cervical tissue. This heterotopia was surrounded by ESCC and connected with it. The present case suggests that some ESCCs may arise in heterotopic cervical epithelium in the endometrium.
authors.affiliation: Department of Pathology and Laboratory Medicine, Kagawa Prefectural Cancer Detection Center, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Izumi
authors.forename: H
authors.initials: H
authors.lastname: Otsuka
authors.forename: Y
authors.initials: Y
authors.lastname: Kishi
authors.forename: T
authors.initials: T
authors.lastname: Mimura
authors.forename: O
authors.initials: O
authors.lastname: Okitsu
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D002584:Cervix Uteri / Q000473:pathology*; D002828:Choristoma / Q000473:pathology* / Q000601:surgery; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007044:Hysterectomy; D012189:Retrospective Studies