[Preoperative treatment with GnRH analogs in hysterectomy].
The authors discuss the usefulness of GnRH analogues inducing, through pituitary desensitization, a transient block of gonadal steroidogenesis--before hysterectomy for uterine leiomyomas. In patients with severe anemia these drugs proved to be very effective in improving the haematologic parameters; they also cause a significant reduction of uterine volume, thus allowing, in selected cases, vaginal hysterectomy in selected cases.
Serrao
L
L
Università degli Studi di Roma, La Sapienza, Istituto di I Clinica Ostetrica e Ginecologica.
Brizzi
C
C
Primiero
F M
FM
D004311:Double-Blind Method; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives*; D017273:Goserelin / Q000627:therapeutic use; D006801:Humans; D007044:Hysterectomy; D007045:Hysterectomy, Vaginal; D007889:Leiomyoma / Q000601:surgery*; D015337:Multicenter Studies as Topic; D011300:Preoperative Care; D016032:Randomized Controlled Trials as Topic; D014594:Uterine Neoplasms / Q000601:surgery*
D017273:Goserelin; D007987:Gonadotropin-Releasing Hormone
Trattamento preoperatorio con analoghi del GnRH nella isterectomia.