Intracellular enhancement of intact antisense oligonucleotide steady-state levels by cationic lipids.
Quattrone
A
A
Institute of General Pathology, University of Florence, Italy.
Papucci
L
L
Schiavone
N
N
Mini
E
E
Capaccioli
S
S
D001483:Base Sequence; D002412:Cations; D002460:Cell Line; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D002467:Cell Nucleus / Q000187:drug effects / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D003593:Cytoplasm / Q000187:drug effects / Q000378:metabolism; D018432:Drug Resistance, Multiple / Q000235:genetics; D005229:Fatty Acids, Monounsaturated / Q000494:pharmacology; D005998:Glycine / Q000031:analogs & derivatives / Q000494:pharmacology; D006801:Humans; D008055:Lipids / Q000494:pharmacology*; D008969:Molecular Sequence Data; D016376:Oligonucleotides, Antisense / Q000378:metabolism*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D013096:Spermine / Q000031:analogs & derivatives / Q000494:pharmacology
D002412:Cations; D005229:Fatty Acids, Monounsaturated; D008055:Lipids; D016376:Oligonucleotides, Antisense; D000644:Quaternary Ammonium Compounds; C054005:N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium; C061134:dioctadecylamidoglycylspermine; D013096:Spermine; C070046:1,2-dioleoyloxy-3-(trimethylammonium)propane; D005998:Glycine