Calculation of dose, dose equivalent, and relative biological effectiveness for high charge and energy ion beams.
The Green's function for the transport of ions of high charge and energy is utilized with a nuclear fragmentation database to evaluate dose, dose equivalent, and RBE for C3H10T1/2 cell survival and neoplastic transformation as a function of depth in soft tissue. Such evaluations are useful to estimates of biological risk for high altitude aircraft, space operations, accelerator operations, and biomedical applications.
Wilson
J W
JW
NASA Langley Research Center, Hampton, VA 23681-0001.
Reginatto
M
M
Hajnal
F
F
Chun
S Y
SY
D000401:Aircraft; D000531:Altitude; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects*; D002471:Cell Transformation, Neoplastic; D004307:Dose-Response Relationship, Radiation; D051379:Mice; D008809:Mice, Inbred C3H; D008962:Models, Theoretical; D009683:Nuclear Medicine; D010315:Particle Accelerators; D013026:Space Flight