title: [Colchicine poisoning apropos of a pediatric case].
abstract: Colchicine has been widely used in the treatment of gout and familial mediterranean fever. Overdose is rare mostly in childhood. Colchicine overdose always causes gastrointestinal side effects, bone marrow depression and sometimes neuropathy. The mechanism of colchicine upon the microtubules, provides a better understanding of the pharmacology and also of the multiorgan involvement. We report the case of a ten year old child who ingested 0.6 mg/kg colchicine with a good outcome.
authors.affiliation: Service de Pharmacie, Hôpital Debrousse, Lyon.
authors.forename: V
authors.initials: V
authors.lastname: Dubois
authors.forename: N
authors.initials: N
authors.lastname: Rey
authors.forename: H
authors.initials: H
authors.lastname: Constant
authors.forename: J M
authors.initials: JM
authors.lastname: Scherrmann
authors.forename: J C
authors.initials: JC
authors.lastname: Berthier
authors.forename: G
authors.initials: G
authors.lastname: Aulagner
mesh_terms: D002648:Child; D003078:Colchicine / Q000008:administration & dosage / Q000378:metabolism / Q000506:poisoning*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans
chemical_list: D003078:Colchicine
vernacular_title: Intoxication à la colchicine à propos d'un cas pédiatrique.