Possible receptor for exfoliative toxins produced by Staphylococcus hyicus and Staphylococcus aureus.
Exfoliative toxin produced by Staphylococcus hyicus bound to the GM4-like glycolipid extracted from the skin of 1-day-old chickens but did not bind to glycolipid from adult chickens or suckling mice. Exfoliative toxin produced by Staphylococcus aureus bound to the GM4-like glycolipid extracted from the skin of suckling mice but not to glycolipid from 1-day-old or adult chickens. S. hyicus and S. aureus exfoliative toxins lost their toxicity by preincubation with GM4-like glycolipid from 1-day-old chickens and suckling mice, respectively.
Tanabe
T
T
Department of Veterinary Microbiology, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan.
Sato
H
H
Ueda
K
K
Chihara
H
H
Watanabe
T
T
Nakano
K
K
Saito
H
H
Maehara
N
N
D000818:Animals; D000833:Animals, Suckling; D002645:Chickens; D005083:Exfoliatins / Q000378:metabolism*; D006017:Glycolipids / Q000378:metabolism*; D051379:Mice; D011956:Receptors, Cell Surface / Q000378:metabolism*; D012867:Skin / Q000382:microbiology; D013210:Staphylococcus / Q000378:metabolism*; D013211:Staphylococcus aureus / Q000378:metabolism*
D005083:Exfoliatins; D006017:Glycolipids; D011956:Receptors, Cell Surface