Melanoma-associated retinopathy.
OBJECTIVE
A 64-year-old man with a history of maxillary antrum melanoma had abrupt-onset night blindness and photopsia.


CONCLUSIONS
Ophthalmologic examination and electroretinogram suggested melanoma-associated retinopathy. Serum produced a weak but specific labeling of human bipolar cells by indirect immunofluorescence. Complete excision of melanoma may have contributed to low levels of circulating autoantibodies. The identity of the retinal bipolar antigen recognized by melanoma-associated retinopathy autoantibodies is needed for more accurate diagnosis.
Singh
A D
AD
Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107.
Milam
A H
AH
Shields
C L
CL
De Potter
P
P
Shields
J A
JA
D004596:Electroretinography; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000150:complications*; D008545:Melanoma / Q000150:complications*; D008875:Middle Aged; D012164:Retinal Diseases / Q000209:etiology*