title: [Gastric emptying of sucrose and maltose and levels of respective disaccharidases in the small intestinal mucosa of adult rats].
abstract: The gastric emptying of sucrose and maltose solutions at different concentrations, with addition of phenol red (6 mg%) used as a marker, was studied in 144 Wistar male rats. The gastric retention was determined 15 minutes after the orogastric infusion of sucrose and maltose solutions at 2.5%, 5% and 10% and volume of 1 and 2 ml/100 g weight of the animal, making 1 use of 12 rats for each volume and concentration. The activities of lactase, sucrase and maltase were evaluated in other eight rat's small intestine. The results demonstrated a maltase/sucrase activity rate of 4:1. The gastric retentions of the maltose solution were significantly higher than sucrose solution at 10% and 5% concentration, either 1 and 2 ml/100 g weight. There were no differences between gastric retention at 2.5% concentration neither with 2 nor 1 ml/100 g weight. As an explanation of these results it is proposed that the faster gastric emptying of sucrose solution 10% and 5% in relation with the same concentrations of maltose is due to a probable saturation of sucrase, that when achieved, interrupts the regulation of gastric emptying, determined by the intestinal receptors.
authors.affiliation: Universidade Federal de Uberlândia.
authors.forename: F de A
authors.initials: Fde A
authors.lastname: Machado
authors.forename: E F
authors.initials: EF
authors.lastname: Collares
mesh_terms: D000818:Animals; D004186:Disaccharidases / Q000378:metabolism*; D005746:Gastric Emptying / Q000502:physiology*; D007413:Intestinal Mucosa / Q000378:metabolism*; D007421:Intestine, Small; D008297:Male; D008320:Maltose / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013395:Sucrose / Q000378:metabolism*
chemical_list: D013395:Sucrose; D008320:Maltose; D004186:Disaccharidases
vernacular_title: Esvaziamento gástrico de sacarose e maltose e os níveis das respectivas dissacaridases na mucosa do intestino delgado de ratos adultos.