title: [The role of anti-tachycardia stimulation in patients with 3rd-generation defibrillators].
abstract: The most effective antitachycardia pacing mode (ATP) is still a matter of debate. Randomized prospective testing of 5 different ATP modes was performed in 82 patients (pts) prior to and after cardioverter defibrillator (ICD) implantation. The 5 ATP modes included 3-4 stimulation attempts with 4-10 adaptive scanning burst pulses. Adaptive burst coupling interval was 75% in mode A, 81% in mode B, 69% in mode C, 72% in mode D, and 88% in mode E. Auto-decremental scanning within bursts was 8 ms in modi A, B, and C, and 10 ms in modus E; autodecremental scanning between bursts was 8 ms in modi B and C, and 10 ms in modus D. During the pre-op electrophysiologic study (EP), termination (TR) of induced ventricular tachycardia (VT) was possible in 69% and by pre-discharge EP in 53%. Acceleration (AC) rates were 16% pre-op and 32% post-op (p = ns). There were no significant differences in TR or AC between modes A-E. During a mean follow-up of 18 +/- 4 (< 1-41) months, 3182 arrhythmia episodes (AE) occurred: 344 AE (11%) were terminated by primary ICD shocks and ATP was attempted in 2838 AE (89%) and was successful in 2576 AE (91%). AC occurred in 87 AE (3%) and ATP was without effect in 175 AE (6%). Our data show that ATP is helpful in patients with third-generation ICDs and is very effective during follow-up. However, there is no ideal ATP-mode visible in the present study.
authors.affiliation: Abteilung Kardiologie, Medizinische Hochschule Hannover.
authors.forename: H J
authors.initials: HJ
authors.lastname: Trappe
authors.forename: P
authors.initials: P
authors.lastname: Pfitzner
authors.forename: J
authors.initials: J
authors.lastname: Heintze
authors.forename: B
authors.initials: B
authors.lastname: Kielblock
authors.forename: P
authors.initials: P
authors.lastname: Wenzlaff
authors.forename: H G
authors.initials: HG
authors.lastname: Fieguth
authors.forename: H
authors.initials: H
authors.lastname: Klein
mesh_terms: D000368:Aged; D000465:Algorithms; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D017147:Defibrillators, Implantable; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D017180:Tachycardia, Ventricular / Q000503:physiopathology / Q000628:therapy*
vernacular_title: Die Bedeutung der antitachykarden Stimulation bei Patienten mit Defibrillatoren der 3. Generation.