title: Increased serotonin levels in physically trained men.
abstract: It has been postulated that exercise training influences monoaminergic systems. The purpose of the present study was to determine the basal level of serum serotonin (5HT) in track and field-trained men (N = 15) and in untrained subjects matched by age, weight and height (N = 15). Serum serotonin levels were determined in blood drawn into dry tubes after a 12-h fast by high performance liquid chromatography utilizing electrochemical detection. Mean (+/- SD) serum serotonin levels were: 141.32 +/- 38.77 ng/ml for trained subjects and 97.77 +/- 30.53 ng/ml for untrained subjects (P < 0.01, Student t-test). These data show that basal serum serotonin levels are increased by exercise training.
authors.affiliation: Laboratório de Neurociência, Disciplina de Neurologia Experimental, Escola Paulista de Medicina, SP, Brasil.
authors.forename: J
authors.initials: J
authors.lastname: Soares
authors.forename: M G
authors.initials: MG
authors.lastname: Naffah-Mazzacoratti
authors.forename: E A
authors.initials: EA
authors.lastname: Cavalheiro
mesh_terms: D000328:Adult; D000367:Age Factors; D001824:Body Constitution; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D010809:Physical Fitness; D012701:Serotonin / Q000097:blood*
chemical_list: D012701:Serotonin