title: Detection of varicella-zoster virus DNA in ocular samples from patients with uveitis but no cutaneous eruption.
abstract: Herpes zoster ophthalmicus is a well-recognised cause of intraocular inflammation, which may become recurrent or chronic after the acute phase has elapsed. Although it commonly presents with the typical rash, cases of ocular zoster with no cutaneous eruption have been well documented. We present two patients with unilateral anterior uveitis complicated by cataract, in whom molecular techniques based on the polymerase chain reaction detected varicella-zoster virus DNA in intraocular material obtained during cataract surgery. Neither patient gave a history of cutaneous eruption.
authors.affiliation: Birmingham & Midland Eye Hospital, UK.
authors.forename: P
authors.initials: P
authors.lastname: Stavrou
authors.forename: S M
authors.initials: SM
authors.lastname: Mitchell
authors.forename: J D
authors.initials: JD
authors.lastname: Fox
authors.forename: M W
authors.initials: MW
authors.lastname: Hope-Ross
authors.forename: P I
authors.initials: PI
authors.lastname: Murray
mesh_terms: D002386:Cataract / Q000150:complications; D004279:DNA, Viral / Q000032:analysis*; D006563:Herpes Zoster Ophthalmicus / Q000175:diagnosis; D014645:Herpesvirus 3, Human / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014606:Uveitis, Anterior / Q000150:complications / Q000821:virology*
chemical_list: D004279:DNA, Viral