Spared descending pathways mediate locomotor recovery after subtotal spinal cord injury.
The location of pathways responsible for locomotor recovery after incomplete spinal cord injury has been studied in adult rats. Animals were allowed to recover from subtotal mid-thoracic cord section which spared left lateral and ventral funiculus fibers. Subsequent lumbar commissurotomy or left thoracic cord hemisection abolished the locomotor recovery. Spared descending fibers passing through the initial incomplete cord lesion appear to mediate locomotor recovery.
Harris
R M
RM
Department of Biological Structure, University of Washington, Seattle 98195.
Little
J W
JW
Goldstein
B
B
D000818:Animals; D003714:Denervation; D005260:Female; D006614:Hindlimb / Q000502:physiology; D008124:Locomotion / Q000502:physiology*; D009068:Movement / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000473:pathology; D013119:Spinal Cord Injuries / Q000473:pathology / Q000503:physiopathology*