title: Oral administration of quercitrin modifies intestinal oxidative status in rats.
abstract: 1. Oral administration of quercitrin to rats for 3 days increases the mucosal glutathione contents in ileum and colon as well as inhibits non-enzymatic lipid peroxidation induced in membrane fractions from jejunal and colonic mucosa. 2. After 7 days of treatment with quercitrin, rat intestinal oxidative status trends to normalize to control rats.
authors.affiliation: Department of Pharmacology, School of Pharmacy, Universidad de Granada, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Galvez
authors.forename: J P
authors.initials: JP
authors.lastname: de la Cruz
authors.forename: A
authors.initials: A
authors.lastname: Zarzuelo
authors.forename: F
authors.initials: F
authors.lastname: Sanchez de Medina
authors.forename: J
authors.initials: J
authors.lastname: Jimenez
authors.forename: F
authors.initials: F
authors.lastname: Sanchez de la Cuesta
mesh_terms: D000284:Administration, Oral; D000818:Animals; D005260:Female; D005978:Glutathione / Q000378:metabolism*; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects*; D011794:Quercetin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
chemical_list: C012526:quercitrin; D011794:Quercetin; D005978:Glutathione