[The effects of extracellular matrix on Sertoli cells of rats in vitro].
This study was performed to observe the effects of extracellular matrix (ECM) on Sertoli cells attachment, spreading and morphology in vitro. The ECM used were FN and LN and biomatrix isolated from the liver and lung. The results showed that FN and LN promoted Sertoli cell attachment and spreading. The Sertoli cells grown on the biomatrix isolated from the lung assumed a columnar shape like that seen in vivo. The cells grown on biomatrix from the liver did not.
Cheng
H
H
Institute of Basic Medical Sciences, CAMS and PUMC, Beijing.
Li
H
H
He
X
X
D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002465:Cell Movement / Q000187:drug effects; D002478:Cells, Cultured; D005109:Extracellular Matrix / Q000502:physiology*; D005353:Fibronectins / Q000494:pharmacology*; D007797:Laminin / Q000494:pharmacology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012708:Sertoli Cells / Q000187:drug effects / Q000502:physiology*
D005353:Fibronectins; D007797:Laminin