Intraocular pressure elevation associated with inhalation and nasal corticosteroids.
BACKGROUND
The ocular hypertensive response to corticosteroids is well established. Elevated intraocular pressure (IOP) secondary to corticosteroids by nasal spray or inhalation has rarely been reported.


RESULTS
Three patients showed a possible ocular hypertensive response to beclomethasone dipropionate by nasal spray or inhalation. In two patients, the IOP returned to pretreatment levels after discontinuing nasal corticosteroid spray. One patient required medication to control IOP with continued inhaled corticosteroid. One patient later demonstrated an ocular hypertensive response to oral steroids.


CONCLUSIONS
Corticosteroids by nasal spray or inhalation may cause ocular hypertension in susceptible patients. The authors recommend surveillance of IOP in patients using these medications.
Opatowsky
I
I
Department of Ophthalmology, University of California, San Diego School of Medicine, La Jolla.
Feldman
R M
RM
Gross
R
R
Feldman
S T
ST
D000280:Administration, Inhalation; D000281:Administration, Intranasal; D000368:Aged; D001249:Asthma / Q000188:drug therapy; D001507:Beclomethasone / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D009798:Ocular Hypertension / Q000139:chemically induced*; D012220:Rhinitis / Q000188:drug therapy
D001507:Beclomethasone