title: [Tuberculosis in La Rioja from 1988 to 1993. Clinical course, localization, influence of human immunodeficiency virus infection, and sensitivity of mycobacterial tests].
abstract: BACKGROUND
  The present study was performed to analyze the evolution of the incidence of tuberculosis in La Rioja (Spain) from January 1988 to March 1993. The influence of factors such as HIV infection and alcoholism was analyzed. The sensitivity of the bacilloscopy in the diagnosis was studied.
  
  
  METHODS
  The cases were collected from the Regional Tuberculosis Program of the Public Health Department in La Rioja, with clinical histories being collected from the Internal Medicine Department of the Hospital San Millán in Logroño. Cases of tuberculosis were microbiologically confirmed by cultures of Mycobacterium tuberculosis.
  
  
  RESULTS
  The total number of cases studied was 649 with the incidence of tuberculosis in La Rioja being 51 cases/100,000 inhabitants in 1992. The mean age of all the patients was 45 years with 80% of the tuberculosis being pulmonary and 20% extrapulmonary. Twelve percent of the patients were HIV+; 18% being extrapulmonary tuberculosis and 10.8% pulmonary tuberculosis, p < 0.02. Pleural and urogenital tuberculosis were present in fewer HIV+ patients. Bacilloscopy was negative requiring a culture for diagnosis in 28.6% of the cases with this circumstance more frequently occurring in the pleural and urogenital forms of the diseases. Treatment has evolved from the use of ethambutol in the first few years to the present use of pyrazinamide.
  
  
  CONCLUSIONS
  No trend towards an increase in the incidence of tuberculosis in the time period studied was observed in La Rioja. Extrapulmonary tuberculosis was the type of tuberculosis most frequently found in HIV positive patients, with pleural and urogenital forms of the disease being less frequently found in these patients. In these case the bacilloscopy was also found to be negative more frequently.
authors.affiliation: Servicio de Medicina Interna, Hospital San Millán, INSALUD, Logroño.
authors.forename: P
authors.initials: P
authors.lastname: Labarga Echeverría
authors.forename: M
authors.initials: M
authors.lastname: Perucha González
authors.forename: E
authors.initials: E
authors.lastname: Jiménez Gómez
authors.forename: F
authors.initials: F
authors.lastname: Antón Botella
authors.forename: N
authors.initials: N
authors.lastname: Calavia Rueda
authors.forename: J
authors.initials: J
authors.lastname: Pinilla Moraza
authors.forename: M I
authors.initials: MI
authors.lastname: Gómez Martínez
authors.forename: A
authors.initials: A
authors.lastname: Milazzo Estefanía
mesh_terms: D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013030:Spain / Q000453:epidemiology; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology
vernacular_title: Tuberculosis en La Rioja de 1988 a 1993. Evolución, localizaciones, influencia de la infección por el virus de la inmunodeficiencia humana y sensibilidad de la baciloscopia.