Detection of medullary carcinoma of the thyroid with I-131 MIBG.
Imaging with I-131 MIBG has proved useful for the detection of pheochromocytoma, neuroblastoma, and other neoplasms of neural crest origin. The authors present a case of a patient who was initially diagnosed as having follicular carcinoma of the thyroid in which I-131 MIBG played a key role in leading to the diagnosis of medullary carcinoma of the thyroid. Local and distant metastases were detected using I-131 MIBG imaging. Uptake of I-131 MIBG by medullary carcinoma of the thyroid has both diagnostic and therapeutic implications.
Thomas
C C
CC
Department of Radiology, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27157-1088.
Cowan
R J
RJ
Albertson
D A
DA
Cooper
M R
MR
D019797:3-Iodobenzylguanidine; D018263:Adenocarcinoma, Follicular / Q000175:diagnosis; D000970:Antineoplastic Agents / Q000627:therapeutic use; D018276:Carcinoma, Medullary / Q000000981:diagnostic imaging* / Q000556:secondary / Q000628:therapy; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D007462:Iodobenzenes / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013671:Technetium Tc 99m Sulfur Colloid; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy
D000970:Antineoplastic Agents; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine; D013671:Technetium Tc 99m Sulfur Colloid