Enhanced isolation of Tyr-MIF-1 from fresh human brain cortex.
Tyr-MIF-1 previously was isolated from tissue obtained after death. A possible role of autolysis could not be excluded. We report the isolation of Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) in increased amounts from fresh human brain cortex. This confirms the natural existence of this brain peptide.
Hackler
L
L
VA Medical Center, New Orleans, LA 70146.
Carey
M E
ME
Kastin
A J
AJ
D002540:Cerebral Cortex / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D009075:MSH Release-Inhibiting Hormone / Q000031:analogs & derivatives* / Q000302:isolation & purification; D011863:Radioimmunoassay
C036930:tyrosyl-prolyl-leucyl-glycinamide; D009075:MSH Release-Inhibiting Hormone