Detection of Mycoplasma fermentans DNA from lymph nodes of acquired immunodeficiency syndrome patients.
Biopsy samples from seven patients with acquired immunodeficiency syndrome were screened for Mycoplasma fermentans, M. pneumoniae and M. genitalium infection by the polymerase chain reaction. M. fermentans DNA was detected in four patients. Various tissues were evaluated and the mycoplasma were mainly detected from lymph nodes. Moreover, mycoplasma genus-specific DNA was isolated from peripheral blood mononuclear cells of asymptomatic human immunodeficiency virus(HIV)-infected individuals (two of 31 HIV-infected individuals). These data suggest that mycoplasma infection in AIDS patients is not uncommon.
Sasaki
Y
Y
Department of Safety Research on Biologics, National Institute of Health, Japan.
Honda
M
M
Naitou
M
M
Sasaki
T
T
D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000382:microbiology; D008198:Lymph Nodes / Q000382:microbiology*; D009174:Mycoplasma / Q000302:isolation & purification; D016858:Mycoplasma fermentans / Q000302:isolation & purification*; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification
D004269:DNA, Bacterial