Extragonadal nonseminomatous germ cell tumour with hypercalcemia, masquerading as renal cell carcinoma: a case report.
Humoral hypercalcemia secondary to the production of parathyroid hormone-related peptide has been reported to occur in up to 17% of patients with renal cell carcinoma but has been reported only rarely in patients with other genitourinary cancers and never in patients with testicular or extragonadal nonseminomatous cancers. A 54-year-old man is reported who had an extragonadal nonseminomatous germ cell tumour with hypercalcemia that masqueraded as a renal cell carcinoma with metastases. The hypercalcemia was suspected to be humorally mediated.
MacDiarmid
S A
SA
Department of Urology, Dalhousie University, Halifax, NS.
Norman
R W
RW
D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000556:secondary; D003937:Diagnosis, Differential; D018240:Endodermal Sinus Tumor / Q000150:complications / Q000175:diagnosis; D017809:Fatal Outcome; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D018243:Teratocarcinoma / Q000150:complications / Q000175:diagnosis*