title: Population genetics of Mycobacterium tuberculosis complex in Scotland analysed by pulsed-field gel electrophoresis.
abstract: The results of typing of 121 strains in the Mycobacterium tuberculosis complex by PFGE are presented. Every isolate from patients in Scotland over a 3-month period for M. tuberculosis and for 1 year for M. bovis were included along with several laboratory strains including those of BCG. The PFGE results suggest that the population structure of all the strains in this complex is distinctly simple with limited genetic diversity and also suggest that M. bovis is not a distinct species.
authors.affiliation: Department of Medical Microbiology, University of Aberdeen.
authors.forename: E S
authors.initials: ES
authors.lastname: Olson
authors.forename: K J
authors.initials: KJ
authors.lastname: Forbes
authors.forename: B
authors.initials: B
authors.lastname: Watt
authors.forename: T H
authors.initials: TH
authors.lastname: Pennington
mesh_terms: D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics*; D016521:Electrophoresis, Gel, Pulsed-Field; D014644:Genetic Variation; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics*; D012606:Scotland / Q000453:epidemiology; D014376:Tuberculosis / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial