Treatment of visceral Leishmaniasis unresponsive to pentamidine with amphotericin B.
Twenty five cases of visceral leishmaniasis unresponsive to Pentamidine were treated with Amphotericin B in the dose schedule of 0.75 mg per kg body weight I.V. on alternate days for total 15 infusions. Full cure was achieved in all twenty five (hundred per cent) cases, no significant toxicity was observed during as well as after treatment and none of the patients relapsed during twelve months follow-up.
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D000293:Adolescent; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010419:Pentamidine / Q000627:therapeutic use*
D010419:Pentamidine; D000666:Amphotericin B