Hepatic involvement culminating in cirrhosis in a child with disseminated cryptococcosis.
A 7-year-old child had unusual manifestation of cryptococcosis; liver and lymph node involvement predominated. There was evidence of cryptococcal hepatitis, extrahepatic biliary obstruction, and subsequent cirrhosis of the liver. Despite widespread dissemination, underlying immune disturbance was not evident. The patient was treated with two courses of amphotericin and 5-flucytosine.
Goenka
M K
MK
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Mehta
S
S
Yachha
S K
SK
Nagi
B
B
Chakraborty
A
A
Malik
A K
AK
D000666:Amphotericin B / Q000627:therapeutic use; D002648:Child; D001651:Cholestasis, Extrahepatic / Q000209:etiology; D003453:Cryptococcosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005437:Flucytosine / Q000627:therapeutic use; D006505:Hepatitis / Q000150:complications* / Q000382:microbiology; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000209:etiology*; D008206:Lymphatic Diseases / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D008297:Male
D000666:Amphotericin B; D005437:Flucytosine