title: Five-year follow-up of nonsecreting pituitary adenomas.
abstract: Nowadays, nonsecreting pituitary adenomas are usually operated on by means of a transsphenoidal approach, and the transseptal way is the most widely used. Since 1982 we have been using lateral rhinotomy instead, resecting bone in the piriform aperture up to the orbit to obtain a good intrasellar view during surgery. In all, 48 patients were operated on between 1982 and 1987, and all of them have since been evaluated in a 5-year follow-up. The only recurrence occurred in the only patient previously operated on transcranially. Computed tomography was performed in 44 patients (92%) after an average of 4 years and revealed no signs of tumor in any of them. New pituitary insufficiencies developed in six (12%). An improvement in vision was observed in 38 patients (79%), none of whom suffered an impaired visual field or acuity. The frequency of new hormonal insufficiencies and improvement of vision that we observed in our patients is comparable with that reported by other investigators, but the recurrence rate is lower and the optic nerves and chiasma were never damaged thereby causing an impairment of vision. These benefits can most probably be explained by the surgical approach we used, in which the tumor and surrounding structures are very well visualized because the operative field is broader and closer than it is with the transseptal approach, which is normally used for this kind of tumor.
authors.affiliation: Department of Otorhinolaryngology, Sahlgren's Hospital, University of Göteborg, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Petruson
authors.forename: K E
authors.initials: KE
authors.lastname: Jakobsson
authors.forename: J
authors.initials: J
authors.lastname: Elfverson
authors.forename: B A
authors.initials: BA
authors.lastname: Bengtsson
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D009666:Nose / Q000601:surgery; D009915:Orbit / Q000601:surgery; D010900:Pituitary Diseases / Q000503:physiopathology; D010902:Pituitary Gland / Q000503:physiopathology; D010911:Pituitary Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D011183:Postoperative Complications; D015996:Survival Rate; D014792:Visual Acuity / Q000502:physiology