title: Distribution and virulence of Vibrio cholerae belonging to serogroups other than O1 and O139: a nationwide survey.
abstract: The distribution and virulence of Vibrio cholerae serogroups other than O1 and O139 in India before, during and after the advent of O139 serogroup was investigated. A total of 68 strains belonging to 31 different 'O' serogroups were identified during the study period. With the exception of O53, there was no spatial or temporal clustering of any particular non-O1 non-O139 serogroup at any given place. Two of the 68 strains examined produced cholera toxin (CT) which could only be partially absorbed with anti-CT immunoglobulin G. Tissue culture assay revealed that some of the non-O1 non-O139 strains produced factors which evoked either a cell rounding or cell elongation response depending upon the medium used. This study indicates that serogroups other than O1 and O139 should also be continuously monitored.
authors.affiliation: National Institute of Cholera and Enteric Diseases, Beliaghata, Calcutta, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Mukhopadhyay
authors.forename: P K
authors.initials: PK
authors.lastname: Saha
authors.forename: S
authors.initials: S
authors.lastname: Garg
authors.forename: S K
authors.initials: SK
authors.lastname: Bhattacharya
authors.forename: T
authors.initials: T
authors.lastname: Shimada
authors.forename: T
authors.initials: T
authors.lastname: Takeda
authors.forename: Y
authors.initials: Y
authors.lastname: Takeda
authors.forename: G B
authors.initials: GB
authors.lastname: Nair
mesh_terms: D000818:Animals; D015373:Bacterial Typing Techniques; D016466:CHO Cells; D002771:Cholera / Q000453:epidemiology / Q000382:microbiology*; D006224:Cricetinae; D006367:HeLa Cells; D006801:Humans; D007194:India / Q000453:epidemiology; D014734:Vibrio cholerae / Q000145:classification* / Q000472:pathogenicity; D014774:Virulence