Psychiatric symptoms, atypical dementia, and left visual field inattention in corticobasal ganglionic degeneration.
We longitudinally examined the neuropsychological and psychiatric characteristics of an adult male with pathologically confirmed corticobasal ganglionic degeneration (CBGD). The patient was seen on an inpatient and outpatient basis by members of the Departments of Neurology and Radiology of the University of Miami School of Medicine. Longitudinal neuropsychological testing revealed a lateralized cortical-subcortical dementia and left visual field inattention consistent with neurological and postmortem neuropathological findings of greater right hemisphere dysfunction. Symptoms of depression and obsessive-compulsive symptomatology were also documented. Our findings are consistent with prior reports indicating that CBGD is characterized by lateralized cerebral dysfunction and suggest that a detailed neuropsychological examination is a useful procedure to assist in the differential diagnosis of this movement disorder.
Rey
G J
GJ
Department of Neurology, University of Miami, Florida 33136.
Tomer
R
R
Levin
B E
BE
Sanchez-Ramos
J
J
Bowen
B
B
Bruce
J H
JH
D000368:Aged; D001480:Basal Ganglia Diseases / Q000175:diagnosis* / Q000523:psychology; D003704:Dementia; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D011569:Psychiatric Status Rating Scales; D014794:Visual Fields