title: Technegas versus krypton-81m gas as an inhalation agent. Comparison of pulmonary distribution at total lung capacity.
abstract: Exactly how the pulmonary distribution of inhaled radioactive gas and Technegas, or ultra-small aerosol particulates, differs from each other, is still uncertain. The authors compared the distribution of inhaled Kr-81 m gas and Technegas in the lungs at total lung capacity in 13 control subjects with no clinical conditions and 13 patients with various chest diseases. In normal lungs, there was no difference in the distribution ratios in the right and left lungs between inhaled Kr-81m gas and Technegas. However, there was a significant difference in the lungs of patients with pulmonary disease. Technegas tended to deposit more in the lung bases than did Kr-81m gas. Despite these statistical differences, they were visually, or qualitatively, similar. From a practical and clinical standpoint, Technegas seems to be useful as an inhalation agent, unless quantitative analyses are required.
authors.affiliation: Department of Medicine, Tohoku University, Sendai 980, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Isawa
authors.forename: T
authors.initials: T
authors.lastname: Teshima
authors.forename: Y
authors.initials: Y
authors.lastname: Anazawa
authors.forename: M
authors.initials: M
authors.lastname: Miki
authors.forename: P S
authors.initials: PS
authors.lastname: Soni
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D005260:Female; D006108:Graphite; D006801:Humans; D007727:Krypton Radioisotopes; D008168:Lung / Q000000981:diagnostic imaging*; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D014018:Tissue Distribution; D014109:Total Lung Capacity
chemical_list: D007727:Krypton Radioisotopes; C056708:Technegas; D006108:Graphite; D013670:Sodium Pertechnetate Tc 99m