The need for three dose levels to detect genotoxic chemicals in in vivo rodent assays.
Hayashi
M
M
Division of Genetics and Mutagenesis, National Institute of Health Sciences, Tokyo, Japan.
Sofuni
T
T
D000818:Animals; D002869:Chromosome Aberrations; D003198:Computer Simulation; D016208:Databases, Factual; D004305:Dose-Response Relationship, Drug; D017408:Guidelines as Topic; D015162:Micronucleus Tests / Q000379:methods; D009010:Monte Carlo Method; D009152:Mutagenicity Tests / Q000379:methods*; D012377:Rodentia