title: [Undifferentiated carcinoma of cervical node metastases in patients with an unknown primary lesion: an immunohistochemical study].
abstract: Sixteen patients with lymphatic metastases to the neck and a histological diagnosis of undifferentiated carcinoma from an unknown primary lesion were assessed using immunohistochemical staining. The results revealed a non-epithelial tumor in 11 cases (malignant lymphoma in 5 cases) and an epithelial tumor in 3 cases. The patients with malignant lymphoma had a good outcome, but those with other non-epithelial tumors did not. Treatment of patients with an unknown primary tumor, especially undifferentiated carcinoma, should be carefully evaluated based on immunohistological examinations to identify malignant lymphoma.
authors.affiliation: Head and Neck Division, Cancer Institute Hospital, Tokyo.
authors.forename: M
authors.initials: M
authors.lastname: Nakamizo
authors.forename: S E
authors.initials: SE
authors.lastname: Kamata
authors.forename: K
authors.initials: K
authors.lastname: Kawabata
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Nigauri
authors.forename: K
authors.initials: K
authors.lastname: Hoki
authors.forename: A
authors.initials: A
authors.lastname: Yanagisawa
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D014408:Biomarkers, Tumor / Q000097:blood; D002277:Carcinoma / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000473:pathology; D009333:Neck; D009382:Neoplasms, Unknown Primary / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor