title: Do turbines with servo-controlled speed improve continuous positive airway pressure generation?
abstract: Nasal continuous positive airway pressure (CPAP) devices with a servo-mechanism to control pressure have recently been developed. We evaluated six such devices and three conventional systems in terms of effectiveness in maintaining constant pressure. Machines were tested with pressure levels of 5, 10 and 15 cmH2O. Dynamic behaviour was evaluated: 1) by calculating the imposed work of breathing during simulated breath generated by a sinusoidal pump; and 2) by following the fall in pressure after a transient flow of 1 l.s-1. Quasi-static behaviour was evaluated by simulating a predetermined air leak. Under dynamic conditions, work of breathing was lowest with one conventional nasal CPAP device and three servo-controlled nasal CPAP devices; whereas, the highest levels of work of breathing were recorded with two servo-controlled nasal CPAP devices. The pressure-time response to a transient flow yielded similar results, with a significant inverse correlation between pressure values observed after 300 ms and imposed work of breathing during simulated breathing (r = -0.91). Under quasi-static conditions, microprocessor servo-controlled devices exhibited the best performance. These results suggest that microprocessor servo-controlled nasal CPAP devices are not always the best systems for maintaining constant airway pressure in dynamic situations. However, they are more effective in ensuring maintenance of the desired pressure in the event of an air leak at the mask.
authors.affiliation: Service de Physiologie-Explorations Fonctionnelles, Hôpital Henri Mondor, Créteil, France.
authors.forename: F
authors.initials: F
authors.lastname: Lofaso
authors.forename: L
authors.initials: L
authors.lastname: Heyer
authors.forename: A
authors.initials: A
authors.lastname: Leroy
authors.forename: H
authors.initials: H
authors.lastname: Lorino
authors.forename: A
authors.initials: A
authors.lastname: Harf
authors.forename: D
authors.initials: D
authors.lastname: Isabey
mesh_terms: D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006801:Humans; D008838:Microcomputers; D008961:Models, Structural; D011175:Positive-Pressure Respiration / Q000295:instrumentation* / Q000379:methods; D014939:Work of Breathing / Q000502:physiology