Laboratory diagnosis of von Willebrand's disease.
The diagnosis of von Willebrand's disease is becoming complex as more is understood about the disease. Clinical information and laboratory data are necessary for the diagnosis because of the overlap of normal and abnormal laboratory values. A complete evaluation including von Willebrand factor multimers, ristocetin-induced platelet aggregation, factor VIII activity level, and a template bleeding time is necessary to correctly classify the patient so that optimal treatment may be given.
Rick
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Hematology Service, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland.
D019411:Clinical Laboratory Techniques / Q000379:methods*; D004587:Electrophoresis, Agar Gel; D006801:Humans; D014842:von Willebrand Diseases / Q000145:classification / Q000175:diagnosis* / Q000235:genetics; D014841:von Willebrand Factor / Q000032:analysis / Q000235:genetics / Q000502:physiology
D014841:von Willebrand Factor