title: Hypertensive encephalopathy after bilateral carotid endarterectomy.
abstract: BACKGROUND
  Hypertension occurs frequently after carotid endarterectomy and may lead to cerebral vascular complications and myocardial infarction. Its pathophysiology has recently been related to surgically induced damage of carotid baroreceptors.
  
  
  METHODS
  A 45-year-old normotensive man with no history of epilepsy was admitted 3 weeks after bilateral carotid endarterectomy for severe repetitive paroxysmal headaches, vomiting, and agitation that were closely associated with attacks of marked hypertension. During one of these attacks, he had a grand mal seizure. Plasma catecholamine levels during hypertensive attacks were highly elevated despite the absence of pheochromocytoma, reflecting abnormalities in baroreceptor sensitivity that lead to unrestrained activation of the central sympathetic nervous system. Heart rate response to Valsalva maneuver showed suppression of the usual tachycardia, indicating baroreceptor reflex insensitivity.
  
  
  CONCLUSIONS
  We report the first case of hypertensive encephalopathy associated with baroreflex failure syndrome after bilateral carotid endarterectomy. The role of blood pressure monitoring may be critical in revealing carotid baroreceptor insensitivity in such clinical settings.
authors.affiliation: Service de Neurologie, Hôpital Lariboisiere, Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Ille
authors.forename: F
authors.initials: F
authors.lastname: Woimant
authors.forename: A
authors.initials: A
authors.lastname: Pruna
authors.forename: O
authors.initials: O
authors.lastname: Corabianu
authors.forename: J M
authors.initials: JM
authors.lastname: Idatte
authors.forename: M
authors.initials: M
authors.lastname: Haguenau
mesh_terms: D017704:Baroreflex / Q000502:physiology; D001927:Brain Diseases / Q000209:etiology*; D016894:Endarterectomy, Carotid / Q000009:adverse effects*; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D006261:Headache / Q000209:etiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000209:etiology; D012021:Reflex, Abnormal / Q000502:physiology; D014636:Valsalva Maneuver / Q000502:physiology; D014839:Vomiting / Q000209:etiology