title: [Lymphoproliferative disease in pediatric liver transplantation].
abstract: Post-Transplant Lymphoproliferative Disorders are due to continuous B-lymphocyte proliferation induced by Epstein-Barr Virus (EBV) infection which is recovered in 88% of transplanted patients. These disorders may present clinically as lymphadenopathic syndrome with lymphoid tissue hyperplasia, systemic as a mononucleosis-like syndrome and lymphomatous syndrome, indistinguishable from non-Hodgkin's lymphoma. We present 10 patients of PTLD classified as 7 lymphadenopathic, 1 systemic (this patient had both syndromes) and 3 lymphomatous tumours. At present, PTLD treatment consists of surgical removal of accessible masses or post-chemotherapy (ChT) tumour rests, total or partial withdrawal of immunosuppressive drugs and ChT following the Sociéte Française d'Oncologie Pédiatrique (SFOP) protocol for non-Hodgkin's lymphoma.
authors.forename: V
authors.initials: V
authors.lastname: Martínez Ibáñez
authors.forename: M
authors.initials: M
authors.lastname: De Diego
authors.forename: H
authors.initials: H
authors.lastname: Allende
authors.forename: C
authors.initials: C
authors.lastname: Ruiz-Marcellán
authors.forename: I
authors.initials: I
authors.lastname: de Torres
authors.forename: T
authors.initials: T
authors.lastname: Español
authors.forename: A
authors.initials: A
authors.lastname: Marqués
authors.forename: J
authors.initials: J
authors.lastname: Boix-Ochoa
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D016031:Liver Transplantation / Q000009:adverse effects; D008232:Lymphoproliferative Disorders / Q000209:etiology* / Q000628:therapy; D008297:Male; D011183:Postoperative Complications; D013997:Time Factors
vernacular_title: Enfermedad linfoproliferativa en el trasplante hepático pediátrico.