title: [Problems of breast conservation therapy].
abstract: Breast conservation therapy (BCT) is now considered an appropriate method to treat stage I-II breast cancer. However, local recurrence after BCT is found in at least 5-10% of the patients. We discussed the problems of BCT, including prognostic factors for local recurrence, optimal surgical technique, management of ductal carcinoma in situ, the clinical usefulness of postsurgical radiotherapy, and the indications for induction chemotherapy for more advanced cases.
authors.affiliation: Dept. of Surgery, National Cancer Center Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Fukutomi
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D017326:Clinical Trials, Phase III as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015337:Multicenter Studies as Topic; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy*; D013629:Tamoxifen / Q000008:administration & dosage
chemical_list: D013629:Tamoxifen