title: Hemopump fails as bridge to transplantation in postinfarction ventricular septal defect.
abstract: From 1990, six patients were bridged to transplantation with a catheter-mounted axial flow pump (Hemopump). Indications were graft failure (two patients), postinfarction ventricular septal defect (two patients), myocarditis (1 patient), and myocardial infarction (1 patient). The 21F cannula, inserted via the groin, was used as a partial assist in four patients, and the 31F cannula, inserted via the ascending aorta, was used to assist the other two patients completely. Hemodynamic recovery was achieved in all patients (mean cardiac index rose from 2.1 L/gm/m2 to 3.85 L/gm/m2 after 1 hour assist). Sudden pump failure occurred in the two patients with postinfarction ventricular septal defect and a piece of necrotic tissue blocking the catheter was found. Both patients died. The other four patients were successfully bridged to transplantation. One of these patients died during his postoperative hospital stay; the three remaining patients were discharged and were well at follow-up (46, 40, and 3 months). The Hemopump device provides sufficient organ perfusion to be used as a bridge to transplantation. No conclusions can be drawn for the long-term use (longest run in this series was 102 hours). Postinfarction ventricular septal defect is a contraindication for the use of the Hemopump device.
authors.affiliation: Department of Cardiac Surgery, Katholieke Universiteit Leuven, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Meyns
authors.forename: H
authors.initials: H
authors.lastname: Vanermen
authors.forename: J
authors.initials: J
authors.lastname: Vanhaecke
authors.forename: P
authors.initials: P
authors.lastname: Sergeant
authors.forename: W
authors.initials: W
authors.lastname: Daenen
authors.forename: W
authors.initials: W
authors.lastname: Flameng
mesh_terms: D000293:Adolescent; D000328:Adult; D002303:Cardiac Output, Low / Q000209:etiology / Q000628:therapy; D000075202:Contraindications; D004868:Equipment Failure; D006084:Graft Rejection / Q000628:therapy; D006342:Heart Rupture, Post-Infarction / Q000601:surgery*; D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000150:complications