Synthesis of new derivatives of 4-acylquinoxalin-2-ones with potential pharmacological activity.
Some of new derivatives of 4-acylquinoxalin-2-one obtained in the reaction of N,N'-bis(chloroacetyl)-4,5-dimethyl-o-phenylenediamine with primary amines are described. Compounds were tested for their anti-HIV activity and as ligands for 99mTc.
Mikiciuk-Olasik
E
E
Department of Synthesis and Technology of Drugs, School of Medicine, Lódź, Poland.
Trzebiński
P
P
Nowak
R
R
Kotełko
B
B
D000998:Antiviral Agents / Q000138:chemical synthesis*; D006678:HIV / Q000187:drug effects*; D008024:Ligands; D011963:Receptors, GABA-A / Q000378:metabolism*
D000998:Antiviral Agents; D008024:Ligands; D011963:Receptors, GABA-A