title: Intrapleural instillation of urokinase in the treatment of loculated pleural effusions in children.
abstract: The authors report on the use of intrapleural instillation of urokinase in the treatment of loculated pleural effusions in two pediatric patients. Urokinase helps to lyse fibrin by converting plasminogen to plasmin. The intrapleural instillation of urokinase is safe and effective for promoting drainage of loculated intrapleural effusions, and it proved a useful option in the treatment of persistent loculations.
authors.affiliation: Department of Surgery, State University of New York at Stony Brook.
authors.forename: G
authors.initials: G
authors.lastname: Stringel
authors.forename: A R
authors.initials: AR
authors.lastname: Hartman
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007322:Instillation, Drug; D008297:Male; D010994:Pleura; D010996:Pleural Effusion / Q000188:drug therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D014568:Urokinase-Type Plasminogen Activator