Protection of cattle against rinderpest and lumpy skin disease with a recombinant capripoxvirus expressing the fusion protein gene of rinderpest virus.
Cattle were protected against challenge with rinderpest and lumpy skin disease viruses by vaccination with a recombinant capripoxvirus containing the fusion protein (F) gene of rinderpest virus. The minimum protective immunising doses for rinderpest and lumpy skin disease were 5.5 x 10(4) plaque forming units (pfu) and 1.5 x 10(3) pfu, respectively.
Romero
C H
CH
Institute for Animal Health, Pirbright Laboratory, Woking, Surrey.
Barrett
T
T
Kitching
R P
RP
Carn
V M
VM
Black
D N
DN
D000818:Animals; D001831:Body Temperature; D018151:Capripoxvirus / Q000276:immunology*; D002417:Cattle; D008166:Lumpy Skin Disease / Q000517:prevention & control*; D012301:Rinderpest / Q000517:prevention & control*; D012302:Rinderpest virus / Q000235:genetics / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary*; D014614:Vaccines, Synthetic; D014760:Viral Fusion Proteins / Q000235:genetics; D014765:Viral Vaccines
D014614:Vaccines, Synthetic; D014760:Viral Fusion Proteins; D014765:Viral Vaccines