The morphological studies on M2/t(8; 21) acute nonlymphocytic leukemia.
Bone marrow studies including morphological, morphometrical and ultrastructural aspects were performed in 35 patients with M2/t(8; 21) and 23 patients with M2/NN. It was found that M2/t(8; 21) patients had higher cellularity in bone marrow. Type (II) myeloblast cells were predominant among myeloblasts. Deformation of nuclei, nucleocytoplasmic asynchronism and dysmegakaryocytopoiesis were more evident in M2/t(8; 21) than in M2/NN patients.
Chen
F J
FJ
Research Institute of Hematology, Xiehe Hospital, Tongji Medical University, Wuhan.
Yang
A D
AD
Fei
H B
HB
D001853:Bone Marrow / Q000648:ultrastructure; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000473:pathology*; D014178:Translocation, Genetic