[Ketanserin and random skin flaps. An experimental study in the rat].
This prospective randomised study in a rodent model was designed to analyse the value of a serotonin antagonist, ketanserin, on the survival of random skin flaps in Wistar rats. Our study demonstrates the statistical value of this molecule. The surface of skin necrosis was statistically lower in the group of rats treated with pre and post operative subcutaneous injection of ketanserin.
Achouche
J
J
Unité de chirurgie plastique, Hôpital Lariboisière, Université Paris VII.
Teisseire
B
B
Laccourreye
O
O
Hadjean
E
E
D000818:Animals; D007650:Ketanserin / Q000494:pharmacology*; D008297:Male; D009336:Necrosis; D011446:Prospective Studies; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D012107:Research Design; D012867:Skin / Q000187:drug effects / Q000473:pathology; D013524:Surgical Flaps
D007650:Ketanserin
Kétansérine et lambeaux cutanés au hasard étude expérimentale chez le rat.