[Effect of furosemide added to peritoneal dialysis fluid on hydroxyproline excretion in dialysate and urine].
The effect of furosemide (1500 mg/21 of peritoneal dialysis fluid) on excretion of hydroxyproline in dialysate and its renal clearance was investigated in 12 patients with end-stage renal disease on regular dialysis treatment. The 37 +/- 8% and 20 +/- 6% increase of D/S ratio of hydroxyproline after 5 and 8 hours of dwell, respectively, and 52 +/- 24% increase of renal clearance of hydroxyproline were induced by furosemide, which indicate its significant influence on peritoneal and renal removal of hydroxyproline.
Sucharzewska-Tomczak
M
M
Kliniki Nefrologii Akademii Medycznej im. Karola Marcinkowskiego w Poznaniu.
Grzegorzewska
A
A
D000328:Adult; D000368:Aged; D015314:Dialysis Solutions / Q000032:analysis*; D005260:Female; D005665:Furosemide / Q000494:pharmacology*; D006801:Humans; D006909:Hydroxyproline / Q000032:analysis / Q000187:drug effects*; D007676:Kidney Failure, Chronic / Q000628:therapy / Q000652:urine*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis
D015314:Dialysis Solutions; D005665:Furosemide; D006909:Hydroxyproline
Wpływ furosemidu podanego podczas dializy otrzewnowej na wydalanie hydroksyproliny z dializatem i moczem.