title: Changes in the basal ganglia and thalamus following reperfusion after complete cerebral ischaemia.
abstract: We report specific changes bilaterally in the basal ganglia and thalamus following reperfusion after complete cerebral ischaemia. A 69-year-old man, resuscitated after cardiac arrest, showed symmetrical low-density lesions in the head of the caudate nucleus and lentiform nucleus on CT. MRI revealed methaemoglobin derived from minor haemorrhage in the basal ganglia and thalamus, not evident on CT. We suggest that this haemorrhage results from diapedesis of red blood cells through the damaged capillary endothelium following reperfusion.
authors.affiliation: Department of Emergency and Critical Care Medicine, Nara Medical University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fujioka
authors.forename: K
authors.initials: K
authors.lastname: Okuchi
authors.forename: S
authors.initials: S
authors.lastname: Miyamoto
authors.forename: T
authors.initials: T
authors.lastname: Sakaki
authors.forename: K
authors.initials: K
authors.lastname: Hiramatsu
authors.forename: M
authors.initials: M
authors.lastname: Tominaga
authors.forename: Y
authors.initials: Y
authors.lastname: Kamada
authors.forename: S
authors.initials: S
authors.lastname: Iwasaki
mesh_terms: D000368:Aged; D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology*; D001929:Brain Edema / Q000000981:diagnostic imaging / Q000473:pathology; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy*; D002421:Caudate Nucleus / Q000000981:diagnostic imaging / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000473:pathology; D003342:Corpus Striatum / Q000000981:diagnostic imaging / Q000473:pathology; D006323:Heart Arrest / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008706:Methemoglobin; D015424:Reperfusion; D012151:Resuscitation; D013788:Thalamus / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D008706:Methemoglobin