title: Aortic dissection repair with GRF glue complicated by heart block.
abstract: Gelatin-resorcin-formaldehyde-glutaraldehyde (GRF) biologic glue is an available adjunct to repair acute ascending aortic dissections. Permanent complete heart block complicated the operative repair of 2 of 6 patients. The pathophysiology of heart block resulting from either the acute dissecting process or the technique of applying GRF glue is discussed.
authors.affiliation: Department of Cardiothoracic Surgery, University of Cape Town, South Africa.
authors.forename: U O
authors.initials: UO
authors.lastname: Von Oppell
authors.forename: D
authors.initials: D
authors.lastname: Chimuka
authors.forename: J G
authors.initials: JG
authors.lastname: Brink
authors.forename: P
authors.initials: P
authors.lastname: Zilla
mesh_terms: D000208:Acute Disease; D000784:Aortic Dissection / Q000150:complications / Q000601:surgery*; D001014:Aortic Aneurysm / Q000150:complications / Q000601:surgery*; D002315:Cardiopulmonary Bypass / Q000379:methods*; D004338:Drug Combinations; D005260:Female; D005557:Formaldehyde / Q000009:adverse effects*; D005780:Gelatin / Q000009:adverse effects*; D006327:Heart Block / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D012118:Resorcinols / Q000009:adverse effects*; D014014:Tissue Adhesives / Q000009:adverse effects*
chemical_list: D004338:Drug Combinations; D012118:Resorcinols; D014014:Tissue Adhesives; C027813:gelatin-resorcinol-formaldehyde tissue adhesive; D005557:Formaldehyde; D005780:Gelatin