title: [Comparative study of 2 diagnostic tests of aspecific bronchial hyperreactivity].
abstract: Bronchial challenge test are useful in diagnosis of bronchial hyperresponsiveness (BH). To assess the sensitivity of histamine test (HT) and exercise test (ET), 45 asthmatic patients (31 men, 14 women, ages 9-34) with normal resting pulmonary function test were studied. HT and ET were performed in two different days. HT was positive in 40 (6 severe, 23 moderate and 11 mild) and ET was positive in 13 (88.8% vr 28.8%, p < 0.001). All patients with positive ET had positive HT. There is a relationship between the degree of BH severity and the response to ET (chi 2 = 5.995; p < 0.05). The HT has a high profitability the diagnosis of BH. The ET has a low sensitivity.
authors.affiliation: Servicio de Neumología, Hospital General Gregorio Marañón, Madrid.
authors.forename: J
authors.initials: J
authors.lastname: García de Pedro
authors.forename: P
authors.initials: P
authors.lastname: de Lucas
authors.forename: A
authors.initials: A
authors.lastname: Arnedillo
authors.forename: L
authors.initials: L
authors.lastname: Puente
authors.forename: E
authors.initials: E
authors.lastname: Tatay
authors.forename: J M
authors.initials: JM
authors.lastname: Monturiol
mesh_terms: D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000175:diagnosis* / Q000503:physiopathology; D016535:Bronchial Hyperreactivity; D001985:Bronchial Provocation Tests; D002648:Child; D005080:Exercise Test; D005260:Female; D006632:Histamine; D006801:Humans; D008297:Male; D012129:Respiratory Function Tests
chemical_list: D006632:Histamine
vernacular_title: Estudio comparativo de dos pruebas de diagnóstico de la hiperreactividad bronquial inespecífica.