Determination of the molecular lesions associated with loss-of-function transformer alleles of Drosophila melanogaster.
Three mutant alleles of the transformer locus, trav1, trav2 and traenu, were analyzed genetically, and all were found to be functionally null alleles. The DNA sequences of these mutants revealed that they represent nonsense mutations that potentially encode truncated Tra polypeptides of 12, 61, and 90 amino acids, respectively.
Yuan
X
X
Department of Biology, Syracuse University, NY 13244.
Belote
J M
JM
D000483:Alleles; D000818:Animals; D004249:DNA Damage; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D008297:Male; D009154:Mutation