title: Transient central hypothyroidism as a cause of failure to thrive in newborns and infants.
abstract: The course of two neonates and one 4-month-old infant with laboratory and clinical evidence of central hypothyroidism is described. All three presented with failure to thrive and improved after L-T4 therapy. Early recognition and treatment of newborns and infants with central hypothyroidism is important to maximize the potential for growth and development. Two of the three infants have been documented to have transient central hypothyroidism of hypothalamic origin, not previously reported.
authors.affiliation: Department of Pediatrics, Loyola University Chicago, Stritch School of Medicine, Maywood, IL.
authors.forename: R
authors.initials: R
authors.lastname: Jain
authors.forename: R M
authors.initials: RM
authors.lastname: Isaac
authors.forename: M E
authors.initials: ME
authors.lastname: Gottschalk
authors.forename: T F
authors.initials: TF
authors.lastname: Myers
mesh_terms: D005183:Failure to Thrive / Q000150:complications / Q000209:etiology*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000188:drug therapy; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D013974:Thyroxine