title: Resolution of lichen planus following removal of amalgam restorations in patients with proven allergy to mercury salts: a pilot study.
abstract: Thirteen patients with symptomatic oral lichen planus had been shown by patch testing to be allergic to ammoniated mercuric chloride. Replacement of amalgam restorations in these patients effected an improvement in all but one case. In some cases the resolution of symptoms was dramatic following the replacement of one or two fillings. The authors feel that the removal of all amalgam fillings need not be necessary except in the most intractable case.
authors.affiliation: Department of Restorative Dentistry, Dental School, University of Newcastle upon Tyne.
authors.forename: E R
authors.initials: ER
authors.lastname: Smart
authors.forename: R I
authors.initials: RI
authors.lastname: Macleod
authors.forename: C M
authors.initials: CM
authors.lastname: Lawrence
mesh_terms: D000328:Adult; D003723:Dental Amalgam / Q000009:adverse effects*; D003793:Dental Restoration, Permanent / Q000009:adverse effects; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D017676:Lichen Planus, Oral / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D008297:Male; D008627:Mercuric Chloride / Q000009:adverse effects*; D008875:Middle Aged; D010865:Pilot Projects; D012086:Reoperation
chemical_list: D008627:Mercuric Chloride; D003723:Dental Amalgam