[The microbiocenosis of the intestinal mucosa during the treatment of infectious urogenital diseases with fluorinated quinolones].
Intestinal microecology was studied in 52 patients (47 females and 5 males aged 18-61) with urogenital infections. Group 1 consisted of 35 patients with new-onset urogenital infections, group 2 of 17 patients had long-term recurrent urogenital infection. All the patients exhibited abnormal intestinal mucosal flora manifest more definitely in group 2. The microfloral changes comprised reduced count of bifidal bacteria, E. Coli, lactobacteria, occurrence of atypical bacteria. Administration of fluorinated quinolones (abactal or maxaquine) affected aerobic intestinal microflora and insignificantly influenced anaerobic bacteria. It is thought valid to investigate intestinal flora in patients with urogenital infections for taking adequate corrective measures.
Kisina
V I
VI
D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000302:isolation & purification; D002175:Candida / Q000302:isolation & purification; D002908:Chronic Disease; D005260:Female; D052776:Female Urogenital Diseases / Q000188:drug therapy* / Q000382:microbiology*; D024841:Fluoroquinolones; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects* / Q000382:microbiology*; D008297:Male; D052801:Male Urogenital Diseases; D008875:Middle Aged; D012008:Recurrence; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology*
D000890:Anti-Infective Agents; D024841:Fluoroquinolones
Mikrobiotsenoz slizistoĭ obolochki kishechnika pri lechenii infektsionnykh urogenital'nykh zabolevaniĭ ftorirovannymi khinolonami.