title: Adrenomedullary function in depressed patients.
abstract: In this paper from the Collaborative Depression Study (CDS)--Biological, a set of data analyses are presented which indicate that depressed states and perhaps depressed mood are associated with a greater activation of the adrenomedullary system than the sympathetic nervous system [as measured by norepinephrine (NE) and normetanephrine excretion]. For the most part this finding of predominant activation of the adrenomedullary system is seen in unipolar and not bipolar patients.
authors.affiliation: Department of Psychiatry, University of Texas Health Science Center at San Antonio 78284-7792.
authors.forename: J W
authors.initials: JW
authors.lastname: Maas
authors.forename: M M
authors.initials: MM
authors.lastname: Katz
authors.forename: S H
authors.initials: SH
authors.lastname: Koslow
authors.forename: A
authors.initials: A
authors.lastname: Swann
authors.forename: J M
authors.initials: JM
authors.lastname: Davis
authors.forename: N
authors.initials: N
authors.lastname: Berman
authors.forename: C L
authors.initials: CL
authors.lastname: Bowden
authors.forename: P E
authors.initials: PE
authors.lastname: Stokes
authors.forename: H
authors.initials: H
authors.lastname: Landis
mesh_terms: D000313:Adrenal Medulla / Q000503:physiopathology*; D000639:Amitriptyline / Q000008:administration & dosage / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy / Q000503:physiopathology* / Q000652:urine; D006801:Humans; D007099:Imipramine / Q000008:administration & dosage / Q000627:therapeutic use; D013564:Sympathetic Nervous System / Q000503:physiopathology
chemical_list: D000639:Amitriptyline; D007099:Imipramine