title: Bioaccumulation and toxic effects of elevated levels of 3,3',4,4'-tetrachloroazobenzene (33'44'-TCAB) towards aquatic organisms. I: A simple method for the rapid extraction, detection and determination of 33'44'-TCAB in multiple biological samples.
abstract: The polychlorinated aromatic compound 3,3',4,4'-tetrachloroazobenzene (33'44'-TCAB) is a contaminant of 3,4-dichloroaniline based herbicides, but there have been no reports of methods for the quantitative determination of 33'44'-TCAB in biological organisms. In this communication we address this knowledge gap by presenting a method for the rapid extraction, detection and determination of 33'44'-TCAB in multiple biological samples based on the alkaline decomposition of the sample followed by alumina cartridge column chromatography and GC-HRMS analysis.
authors.affiliation: National Institute for Environmental Studies, Ibaraki, Japan.
authors.forename: G
authors.initials: G
authors.lastname: Allinson
authors.forename: M
authors.initials: M
authors.lastname: Morita
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D001391:Azo Compounds / Q000302:isolation & purification* / Q000493:pharmacokinetics; D002722:Chlorobenzenes / Q000302:isolation & purification* / Q000493:pharmacokinetics; D005506:Food Contamination / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D009990:Oryzias / Q000378:metabolism*
chemical_list: D001391:Azo Compounds; D002722:Chlorobenzenes; C013279:3,4,3',4'-tetrachloroazobenzene