title: Effectiveness and sequelae of very low-dose suxamethonium for nasal intubation.
abstract: We have studied the effectiveness and sequelae of low-dose suxamethonium in 60 day-case oral surgery patients requiring nasal intubation. Anaesthesia was induced with propofol and alfentanil; 60 patients were allocated randomly to three groups of 20 patients and received no suxamethonium, suxamethonium 0.25 mg kg-1 or 0.5 mg kg-1. All patients received i.v. fentanyl and diclofenac 100 mg rectally for analgesia. Good intubating conditions were produced in all 20 patients receiving suxamethonium 0.25 mg kg-1, in 19 patients receiving suxamethonium 0.5 mg kg-1 and in 11 patients not receiving a neuromuscular blocker. The incidence of postoperative myalgia after suxamethonium 0.25 mg kg-1 (20%) did not differ significantly from the incidence after propofol and alfentanil alone (28%).
authors.affiliation: Anaesthetic Department, Falkirk and District Royal Infirmary, Glasgow.
authors.forename: S M
authors.initials: SM
authors.lastname: Nimmo
authors.forename: N
authors.initials: N
authors.lastname: McCann
authors.forename: I J
authors.initials: IJ
authors.lastname: Broome
authors.forename: H M
authors.initials: HM
authors.lastname: Robb
mesh_terms: D000293:Adolescent; D000328:Adult; D015760:Alfentanil; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000187:drug effects; D015742:Propofol; D013390:Succinylcholine / Q000008:administration & dosage*
chemical_list: D015760:Alfentanil; D013390:Succinylcholine; D015742:Propofol