title: Immunocharacterization of H-2Kb-tsA58 transgenic mouse hippocampal neuroepithelial cells.
abstract: From dissected fragments of embryonic H-2Kb-tsA58 transgenic mouse hippocampal neuroepithelium, we have derived a population of rapidly proliferating, nestin-positive conditionally immortal hippocampal neuroepithelial cells. Treatment with dibutyryl cAMP in non-permissive culture conditions resulted in cessation of cell division and differentiation of the precursor cells into neuronal or glial phenotypes.
authors.affiliation: Neurodegenerative Diseases Research Group, Institute of Psychiatry, De Crespigny Park, London, UK.
authors.forename: T R
authors.initials: TR
authors.lastname: Kershaw
authors.forename: F
authors.initials: F
authors.lastname: Rashid-Doubell
authors.forename: J D
authors.initials: JD
authors.lastname: Sinden
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D004847:Epithelial Cells; D006624:Hippocampus / Q000737:chemistry* / Q000166:cytology; D007150:Immunohistochemistry; D051379:Mice; D008822:Mice, Transgenic