Immunoassay reagents for psychoactive drugs. Part 5. Quantitative determination of imipramine and desipramine by fluorescence polarization immunoassay.
Two methods for the quantitative determination of imipramine (IMI) and desipramine (DMI) by fluorescence polarization immunoassay (FPIA) are described. One immunoassay allows for the accurate quantification of imipramine in the presence of desipramine, while the other allows for the accurate quantification of desipramine in the presence of imipramine.
Adamczyk
M
M
Abbott Laboratories, Abbott Park, Illinois 60064.
Fishpaugh
J R
JR
Harrington
C A
CA
Orsulak
P
P
Akers
L
L
D002851:Chromatography, High Pressure Liquid; D003891:Desipramine / Q000032:analysis*; D004347:Drug Interactions; D016231:Fluorescence Polarization Immunoassay; D006801:Humans; D007099:Imipramine / Q000032:analysis*; D011619:Psychotropic Drugs / Q000032:analysis*
D011619:Psychotropic Drugs; D007099:Imipramine; D003891:Desipramine