title: [Premature rupture of the membranes. Spontaneous course of the event and the therapeutic approach with a human fibrin glue].
abstract: The results of the analysis of 47 cases of premature rupture of the membranes occurred between 20 and 35 weeks of gestation were reviewed. The aim is to evaluate the natural outcome of this pathology and the advantage of the endocervical application of a human fibrin glue (Tissucol) as a treatment of the cases of premature rupture between 20 and 27 weeks of gestation. This management has been performed at the Obstetric Department of the Università de Verona since 1991 on a total of 5 cases. We demonstrated an evident prolongation of pregnancy leading as a consequence to an increased fetal survival rate. Actually the most important risk factor has to be identified in prematurity.
authors.affiliation: Università degli Studi di Verona, Clinica Ostetrica e Ginecologica.
authors.forename: A
authors.initials: A
authors.lastname: Catalano
authors.forename: E
authors.initials: E
authors.lastname: Zardini
mesh_terms: D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000628:therapy*; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome
chemical_list: D015718:Fibrin Tissue Adhesive
vernacular_title: La rottura intempestiva delle membrane. Evoluzione spontanea dell'evento e suo approccio terapeutico mediante una colla di fibrina umana.