Serial MR after bone marrow transplantation in two patients with metachromatic leukodystrophy.
Two children with metachromatic leukodystrophy underwent bone marrow transplantation. In both patients MR subsequently showed, first, white matter changes, then later, lack of change as the patients stabilized clinically.
Stillman
A E
AE
Department of Radiology, University of Minnesota Hospital, Minneapolis 55455.
Krivit
W
W
Shapiro
E
E
Lockman
L
L
Latchaw
R E
RE
D000293:Adolescent; D016026:Bone Marrow Transplantation / Q000473:pathology*; D001921:Brain / Q000473:pathology*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006720:Homozygote; D006801:Humans; D007966:Leukodystrophy, Metachromatic / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination