title: [Autosomal dominant cerebral seizures in the 6th month of life with benign outcome].
abstract: We report a boy with benign familial seizures of the sixth month of life. At the age of six months he suffered his first afebrile grand mal seizure. Up to his ninth month several seizures of the same type occurred. EEGs were always normal. The history yielded a paternal hereditary trait: five members of the family had also suffered grand mal seizures in the sixth month of life. All but one had no therapy with antiepileptic drugs. One girl was treated with phenobarbital for two years. All members of the family show normal neurological development. Under low dose therapy with phenobarbital our patient has remained seizure-free up to now.
authors.affiliation: Universitäts-Kinderklinik, Bereich Neuropädiatrie, Münster.
authors.forename: G
authors.initials: G
authors.lastname: Kurlemann
authors.forename: P
authors.initials: P
authors.lastname: Vossschulte
authors.forename: J
authors.initials: J
authors.lastname: Weglage
authors.forename: D G
authors.initials: DG
authors.lastname: Palm
mesh_terms: D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography / Q000187:drug effects; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D005799:Genes, Dominant / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male; D010375:Pedigree; D010634:Phenobarbital / Q000008:administration & dosage; D013036:Spasms, Infantile / Q000188:drug therapy / Q000235:genetics*
chemical_list: D010634:Phenobarbital
vernacular_title: Autosomal dominante zerebrale Krampfanfälle des sechsten Lebensmonats mit gutartigem Verlauf.