Soluble CTLA4Ig modifies acute rejection of rat lung allografts without blocking accumulation of key cytokine transcripts.
Matsumura
Y
Y
Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California 90048.
Zuo
X J
XJ
Prehn
J
J
Linsley
P
P
Marchevsky
A
A
Kass
R
R
Matloff
J
J
Jordan
S C
SC
D000069594:Abatacept; D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000627:therapeutic use*; D060908:CTLA-4 Antigen; D016207:Cytokines / Q000096:biosynthesis*; D018076:DNA, Complementary; D015870:Gene Expression / Q000276:immunology*; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control*; D018796:Immunoconjugates; D007165:Immunosuppression Therapy / Q000379:methods; D016040:Lung Transplantation / Q000276:immunology*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use; D014158:Transcription, Genetic; D014184:Transplantation, Homologous; D014185:Transplantation, Isogeneic
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556708:Ctla4 protein, rat; D016207:Cytokines; D018076:DNA, Complementary; D018796:Immunoconjugates; D012333:RNA, Messenger; D011993:Recombinant Fusion Proteins; D000069594:Abatacept