[Diagnostic and therapeutic strategy in multiple insulinoma].
Four of 59 patients with organic hyperinsulinism had multiple insulinomas and two patients a micro- and macroadenomatosis. Excluding patients with adenomatosis 3 of 10 tumors could be detected preoperatively by ultrasound (5 of 10 by CT). 6 of 7 macroadenomas could be visualized by angiography. Intraoperatively 9 of 10 macroadenomas were palpable. The nonpalpable tumor could be localized by intraoperative ultrasound. Pancreatic resection had better results than multiple enucleations. Excisional biopsy is recommended to exclude nesidioblastosis or microadenomatosis.
Böttger
T
T
Klinik und Polikinik für Allgemein- und Abdominalchirurgie, Johannes-Gutenberg-Universität Mainz.
Heintz
A
A
Junginger
T
T
Düber
C
C
Beyer
J
J
D007516:Adenoma, Islet Cell / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D007340:Insulinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D010179:Pancreas / Q000473:pathology; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
Diagnostische und therapeutische Strategie bei multiplen Insulinomen.