title: [Diprivan: intubation without curare].
abstract: To intubate under ideal conditions, i.e. with the vocal cords abducted and no motor response to the insertion of the endotracheal tube, the anaesthetist has two alternatives: to use muscle relaxants or to anaesthetize the patient deeply. Apart from cases where muscle relaxants are contra-indicated or required by the type of procedure: Intubation using muscle relaxants means: maintaining the option of varying the depth of anaesthesia, while keeping optimal conditions for intubation; reducing the risk of airways trauma. Intubation without muscle relaxants means: avoiding the risk of allergic complications; producing deep anaesthesia and controlling any resulting haemodynamic effects. The recommended induction agent is propofol, given as a bolus injection at a dose equal to or greater than 2.5 mg.kg-1 in adults and 3.5 mg.kg-1 in children. Alfentanil is the opioid of choice, the dose being between 30 and 40 micrograms.kg-1. Lidocaine, injected as premedication at a dose of 1.5 mg.kg-1 potentiates the effect of alfentanil. The order of injection of the induction agents is important, as it determines the exact moment for laryngoscopy and intubation.
authors.affiliation: Hôpital Henri-Mondor, Créteil.
authors.forename: G
authors.initials: G
authors.lastname: D'Honneur
mesh_terms: D000771:Anesthesia, Intravenous / Q000379:methods; D003472:Curare; D006801:Humans; D007442:Intubation, Intratracheal; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage; D015742:Propofol
chemical_list: D009466:Neuromuscular Blocking Agents; D003472:Curare; D015742:Propofol
vernacular_title: Diprivan: intubation sans curare.