[Models of the organization of neonatal screening].
The authors evaluate the different organizational strategies of a congenital hypothyroidism screening program. Positive and negative aspects of laboratory screening tests (TSH only, T4-supplemental TSH, TSH and T4), organization strategies (centralization or decentralization), recall and first follow-up criteria are examined. The authors consider that the necessity for an early diagnostic confirmation can be associated with a precise etiologic diagnosis and an evaluation of the prenatal severity of congenital hypothyroidism factors. Some European and North-American experiences are compared with the activity of a regional Italian screening center.
Cassio
A
A
I Clinica Pediatrica, Università degli Studi, Bologna.
Piazzi
S
S
Colli
C
C
Balsamo
A
A
Bozza
D
D
Salardi
S
S
Sprovieri
G
G
Cacciari
E
E
D003409:Congenital Hypothyroidism; D005188:False Negative Reactions; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000517:prevention & control; D007231:Infant, Newborn; D007558:Italy; D017146:Models, Organizational; D015997:Neonatal Screening / Q000458:organization & administration*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
D013972:Thyrotropin; D013974:Thyroxine
Modelli di organizzazione degli screening neonatali.