title: Hypometabolism and dipole localization in hemimegalencephaly: a case report.
abstract: A case of hemimegalencephaly was studied by means of neuroimaging (CT, MRI and PET) and magnetoencephalography (MEG). Hemimegalencephaly (HM) is a neuronal migration disorder. This is the first report of evaluation of HM with the use of PET and MEG from not only the morphological but also the functional point of view. PET with 11C-glucose showed a low radioactive concentration in the affected hemisphere, which suggested a metabolic deficit. MEG proved the epileptic foci existed mainly in the affected hemisphere, especially around a heterotopia and the pachygyric cortex, which was disclosed on MRI.
authors.affiliation: Department of Pediatrics, Teikyo University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ohta
authors.forename: M
authors.initials: M
authors.lastname: Hiraiwa
authors.forename: K
authors.initials: K
authors.lastname: Murayama
authors.forename: M
authors.initials: M
authors.lastname: Nonaka-Mishima
authors.forename: Y
authors.initials: Y
authors.lastname: Kaneko
authors.forename: M
authors.initials: M
authors.lastname: Yumoto
authors.forename: H
authors.initials: H
authors.lastname: Yotsumoto
authors.forename: M
authors.initials: M
authors.lastname: Iio
mesh_terms: D001921:Brain / Q000002:abnormalities* / Q000378:metabolism* / Q000503:physiopathology; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
chemical_list: D005947:Glucose