Intramuscular pressure, torque and swelling for the exercise-induced sore vastus lateralis muscle.
This study investigated changes in intramuscular fluid pressure (IMP), torque and swelling related to delayed onset muscle soreness (DOMS) of the vastus lateralis muscle. IMP was measured via catheterization in the unstretched (0 degree, full extension) and stretched (90 degrees of knee flexion) muscle at rest; then IMP and knee extension torque were determined during maximal contractions pre and 2 d after (post) repetitive eccentric activity in one leg for eight male subjects. DOMS of the vastus lateralis muscle was associated with a significant elevation in IMP at rest as indicated by pre (0 degree: 5.4 mmHg, 90 degrees: 80 mmHg) and post (0 degree: 8.4 mmHg, 90 degrees: 13.2 mmHg) comparisons (P = 0.02). Soreness symptoms were aggravated when the muscle was stretched and this was accompanied by a significantly higher post IMP at 90 degrees vs. 0 degree (P = 0.01). During maximal contractions, peak torque declined by 15% relative to pre and peak IMP declined by 26%; DOMS symptoms, however, were most severe during this manoeuvre. Biopsies from the sore vastus lateralis muscle revealed significantly larger fibre areas for all fibre types as compared with contralateral controls (P < 0.01); however, no differences were detected for extracellular volume percent comparisons. This study shows that DOMS of the vastus lateralis muscle is associated with extensive intracellular swelling and with elevated IMP. In line with previous studies, fibre swelling may be a common subsequence to repetitive eccentric activity; the ability of IMP measurements to detect this swelling at rest and during various manoeuvres for other muscles may depend on compartmental compliance.
Crenshaw
A G
AG
Department of Anatomy, Umeå University, Sweden.
Thornell
L E
LE
Fridén
J
J
D000328:Adult; D001706:Biopsy; D004487:Edema / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology*; D005110:Extracellular Space / Q000502:physiology; D006801:Humans; D007424:Intracellular Fluid / Q000502:physiology; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D018485:Muscle Fibers, Skeletal / Q000473:pathology; D018482:Muscle, Skeletal / Q000473:pathology / Q000503:physiopathology*; D010146:Pain / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D011312:Pressure