title: Current status of coronary artery bypass grafting in patients 70 years of age and older.
abstract: One hundred and seventy patients 70 years of age and older underwent isolated coronary artery bypass grafting (CABG) from January 1990 to December 1991 at St. Vincent's Hospital, Melbourne, Australia. The clinical records of these patients were analysed to investigate whether elderly patients could undergo safe coronary artery surgery and to determine the factors affecting the outcome. The 30 day or in-hospital mortality was 2.9% (5/170), with 80% (4/5) of the deaths due to cardiac causes. Major postoperative complications occurred in 22.3% (38/170) patients. The median postoperative hospital stay for the patients was 8 days (range 3-103 days). Univariate analysis identified hypertension and female gender as pre-operative risk factors and intraaortic balloon pump, prolonged ventilation, infarct, tamponade, need for inotropes, renal failure and a high APACHE II scores in the intensive care unit as postoperative significant risk factors for operative mortality. There was a trend towards increased mortality with emergency operations; the operative mortality was 2.1% (2/97) for elective operations, 3.1% (2/64) in urgent cases and 11.1% (1/9) for emergencies. Multivariate logistic regression analysis identified prolonged mechanical ventilation, perioperative infarct and APACHE II score as significant independent predictors of mortality. The low operative mortality indicates that elderly patients can undergo safe revascularization. A high incidence of complications necessitates careful monitoring but age per se should not be considered a contraindication to isolated CABG.
authors.affiliation: Open Heart Surgery Unit, St. Vincent's Hospital, Melbourne, Victoria, Australia.
authors.forename: A S
authors.initials: AS
authors.lastname: Gehlot
authors.forename: J D
authors.initials: JD
authors.lastname: Santamaria
authors.forename: A L
authors.initials: AL
authors.lastname: White
authors.forename: G C
authors.initials: GC
authors.lastname: Ford
authors.forename: K L
authors.initials: KL
authors.lastname: Ervine
authors.forename: A C
authors.initials: AC
authors.lastname: Wilson
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass / Q000401:mortality; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D011182:Postoperative Care; D011183:Postoperative Complications; D012307:Risk Factors