title: Epidemiological studies on Schistosoma mansoni infection in the western region of Saudi Arabia using the potassium hydroxide stool digestion technique.
abstract: The potassium hydroxide stool digestion technique was used in 30 sites in the Western Region of Saudi Arabia (Hijaz highlands and Tihamah lowlands) for epidemiological studies of S. mansoni. The mean prevalence rate in 2792 individuals (1490 males and 1302 females) in Hijaz highlands (20 sites) was 6.09 (0.5-20.1%) and the geometric mean egg count of stool was 110.8 (63-285). The prevalence rate was greater in males (8.06%) than in females (3.79%). The peak prevalence in males was in the age group 11-15 years, and 31-50 years in females. In 10 sites in the Tihamah lowlands a total of 1771 persons were examined for schistosomiasis. Only one site was recorded with S. mansoni, at a prevalence rate of 0.05%; S. haematobium was recorded in two sites at prevalence rates of 0.55 and 1.13%. Praziquantel therapy (40 mg kg-1) of 170 S. mansoni cases showed a cure of 85-98% at 1-6 months after treatment and a considerable reduction in stool arithmetic mean egg count. Schistosoma haematobium was not recorded in the Hijaz highlands.
authors.affiliation: Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: A M
authors.initials: AM
authors.lastname: Ghandour
authors.forename: A A
authors.initials: AA
authors.lastname: al-Robai
authors.forename: M
authors.initials: M
authors.lastname: Doenhoff
authors.forename: A A
authors.initials: AA
authors.lastname: Banaja
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000469:parasitology*; D005260:Female; D006801:Humans; D006878:Hydroxides; D007223:Infant; D008297:Male; D008875:Middle Aged; D010270:Parasite Egg Count; D017680:Potassium Compounds; D011223:Praziquantel / Q000627:therapeutic use; D015995:Prevalence; D012494:Sampling Studies; D012529:Saudi Arabia / Q000453:epidemiology; D012555:Schistosomiasis mansoni / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology*; D012720:Severity of Illness Index; D017678:Sex Distribution; D016896:Treatment Outcome
chemical_list: D006878:Hydroxides; D017680:Potassium Compounds; D011223:Praziquantel; C029943:potassium hydroxide