title: Synthesis of new derivatives of 4-acylquinoxalin-2-ones with potential pharmacological activity.
abstract: Some of new derivatives of 4-acylquinoxalin-2-one obtained in the reaction of N,N'-bis(chloroacetyl)-4,5-dimethyl-o-phenylenediamine with primary amines are described. Compounds were tested for their anti-HIV activity and as ligands for 99mTc.
authors.affiliation: Department of Synthesis and Technology of Drugs, School of Medicine, Lódź, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Mikiciuk-Olasik
authors.forename: P
authors.initials: P
authors.lastname: Trzebiński
authors.forename: R
authors.initials: R
authors.lastname: Nowak
authors.forename: B
authors.initials: B
authors.lastname: Kotełko
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis*; D006678:HIV / Q000187:drug effects*; D008024:Ligands; D011963:Receptors, GABA-A / Q000378:metabolism*
chemical_list: D000998:Antiviral Agents; D008024:Ligands; D011963:Receptors, GABA-A