Detection of mip gene by PCR for diagnosis of Legionnaires' disease.
The mip gene of Legionella pneumophila was demonstrated by PCR and probing in paired acute-phase and convalescent-phase sera from five patients with Legionnaires' disease but not in the acute-phase sera of 100 patients with pneumonia that showed no serological evidence of Legionella infection. PCR may help in cases presenting diagnostic difficulty.
Lindsay
D S
DS
Scottish Legionella Reference Laboratory, Department of Laboratory Medicine, Ruchill Hospital, Glasgow.
Abraham
W H
WH
Fallon
R J
RJ
D004269:DNA, Bacterial / Q000032:analysis*; D005798:Genes, Bacterial / Q000235:genetics*; D006801:Humans; D016952:Legionella pneumophila / Q000235:genetics*; D007877:Legionnaires' Disease / Q000175:diagnosis*; D016133:Polymerase Chain Reaction
D004269:DNA, Bacterial