title: The effect of unilateral injury to the vas deferens on the contralateral testis in immature and adult rats.
abstract: The relationship between alterations in testicular histology and antisperm antibodies in immature and mature Lewis rats subjected to unilateral vasectomy was studied. Forty percent of immature rats and 90% of mature rats (p < 0.01) demonstrated significant alterations in both the obstructed (vasectomy) testis and the contralateral testis. There were significant changes in antisperm antibodies (ELISA) in the animals which demonstrated histologic changes.
authors.affiliation: Division of Urology, St. John's Mercy Medical Center, St. Louis, Missouri 63141-8277.
authors.forename: M J
authors.initials: MJ
authors.lastname: Chehval
authors.forename: S A
authors.initials: SA
authors.lastname: Martin
authors.forename: N J
authors.initials: NJ
authors.lastname: Alexander
authors.forename: T
authors.initials: T
authors.lastname: Winkelmann
mesh_terms: D000367:Age Factors; D000818:Animals; D001323:Autoantibodies / Q000032:analysis; D003251:Constriction, Pathologic; D004797:Enzyme-Linked Immunosorbent Assay; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D012671:Seminiferous Tubules / Q000473:pathology; D013094:Spermatozoa / Q000276:immunology; D013737:Testis / Q000473:pathology*; D014649:Vas Deferens / Q000293:injuries* / Q000473:pathology*; D014659:Vasectomy
chemical_list: D001323:Autoantibodies