Expression of Fos-protein activated by tactile stimulation on the laryngeal vestibulum in the cat's lower brain stem.
To demonstrate morphologically the neurons participating in the laryngeal reflex, Fos-expression, activated with tactile stimulation of the laryngeal vestibulum, was mapped in the cat's lower brain stem utilizing immunohistochemistry. In the stimulation group, many Fos-immunoreactive (ir) neurons were recognized in the nucleus tractus solitarii (NTS) from the level of the most rostral portion of the dorsal motor nucleus of the vagus to the level of the most caudal portion of the inferior olivary nucleus (IO), and in the nucleus ambiguus (NA) from the level of the rostral end of the hypoglossal nucleus to the level of the caudal end of the IO, bilaterally. While some Fos-ir cells were found in the spinal nucleus of the trigeminus, they were also found in the reticular nuclei bilaterally. In the control group, Fos-ir cells were distinctly fewer in number than those in the stimulation group. The results suggested that in the brain stem, the laryngeal reflex pathways have more than two synaptic relays through the interneurons in between the NTS and the NA.
Tanaka
Y
Y
Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Kurume University, Japan.
Yoshida
Y
Y
Hirano
M
M
D000818:Animals; D001933:Brain Stem / Q000378:metabolism*; D002415:Cats; D007150:Immunohistochemistry; D007395:Interneurons / Q000378:metabolism; D007823:Laryngeal Nerves / Q000502:physiology*; D009434:Neural Pathways; D010812:Physical Stimulation; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism*; D012018:Reflex; D009435:Synaptic Transmission
D016760:Proto-Oncogene Proteins c-fos