title: Involvement of a nodofascicular connection in supraventricular tachycardia with VA dissociation.
abstract: We present the case of a patient with episodes of supraventricular tachycardia and atrial dissociation that were terminated by either adenosine or verapamil. Involvement of an accessory pathway was shown by ventricular extrastimuli, elicited during His-bundle refractoriness, that interrupted the tachycardia or advanced the next His potential. The tachycardia circuit was demonstrated to be confined to the nodofascicular region based on the exclusion of surrounding tissues. Atrial activity, including that in the perinodal region, was totally dissociated during tachycardia. The lowest part of the circuit was determined to be located above the Hisian bifurcation, as multiple episodes with either a right or left bundle branch configuration during tachycardia did not modify the HH cycle. The ventricular septum summit was determined not to be involved, as no preexcitation was present during tachycardia or atrial pacing, and the right bundle branch was not part of the circuit. Radiofrequency current applied beneath the tricuspid valve at the His region successfully eliminated the nodofascicular connection with preservation of 1:1 AV conduction. The anatomical substrate underlying the abnormal connection may be either nodofasciculoventricular Mahaim fibers or a duality or dispersion of the nodo-Hisian conducting system.
authors.affiliation: Centre Hospitalier et Universitaire de Bordeaux, Hôpital Cardiologique du Haut-Lévêque, Bordeaux-Pessac, France.
authors.forename: M
authors.initials: M
authors.lastname: Haïssaguerre
authors.forename: J
authors.initials: J
authors.lastname: Campos
authors.forename: F I
authors.initials: FI
authors.lastname: Marcus
authors.forename: G
authors.initials: G
authors.lastname: Papouin
authors.forename: J
authors.initials: J
authors.lastname: Clémenty
mesh_terms: D000328:Adult; D002036:Bundle of His / Q000601:surgery; D017115:Catheter Ablation; D004568:Electrodiagnosis; D006325:Heart Atria; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000503:physiopathology*; D014261:Tricuspid Valve