title: Bioaccumulation and toxic effects of elevated levels of 3,3',4,4'-tetrachloroazobenzene (33'44'-TCAB) towards aquatic organisms. II: Bioaccumulation and toxic effects of dietary 33'44'-TCAB on the Japanese Medaka (Oryzias latipes).
abstract: The polychlorinated aromatic compound 3,3',4,4'-tetrachloroazobenzene (33'44'-TCAB) is a contaminant of 3,4-dichloroaniline (3,4-DCA) based herbicides, and of agricultural soils. In this study, the Japanese Medaka (Oryzias latipes) was exposed to 0.5-2500 ppm 33'44'-TCAB through its diet. There was a distinct trend towards increased mortality and increased body burdens of 33'44'-TCAB with increasing 33'44'-TCAB charge in the food. At the highest levels of exposure, there was a significant number of excess deaths compared to control groups.
authors.affiliation: National Institute for Environmental Studies, Ibaraki, Japan.
authors.forename: G
authors.initials: G
authors.lastname: Allinson
authors.forename: M
authors.initials: M
authors.lastname: Morita
mesh_terms: D000821:Animal Feed; D000818:Animals; D001391:Azo Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000633:toxicity*; D001822:Body Burden; D002722:Chlorobenzenes / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000633:toxicity*; D005506:Food Contamination; D009990:Oryzias / Q000378:metabolism*
chemical_list: D001391:Azo Compounds; D002722:Chlorobenzenes; C013279:3,4,3',4'-tetrachloroazobenzene