title: Function of minor polypeptides in foot-and-mouth disease virus and poliovirus.
abstract: Foot-and-mouth disease virus and poliovirus each contain several minor polypeptides, in addition to the four structural proteins. One of these, the viral RNA polymerase, can also act as a nuclease, hydrolysing the RNA and thus destroying viral infectivity. It is tightly bound to the RNA and may be the packaging signal for assembly of the particle.
authors.affiliation: US Dept of Agriculture, Plum Island Animal Disease Center, Greenport, NY 11944.
authors.forename: J F
authors.initials: JF
authors.lastname: Newman
authors.forename: P G
authors.initials: PG
authors.lastname: Piatti
authors.forename: M D
authors.initials: MD
authors.lastname: Ryan
authors.forename: F
authors.initials: F
authors.lastname: Brown
mesh_terms: D005537:Aphthovirus / Q000737:chemistry*; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry / Q000502:physiology*; D010455:Peptides / Q000737:chemistry / Q000502:physiology; D017955:Poliovirus / Q000737:chemistry*; D012367:RNA, Viral / Q000235:genetics / Q000378:metabolism; D015678:Viral Structural Proteins / Q000737:chemistry / Q000502:physiology*
chemical_list: D010455:Peptides; D012367:RNA, Viral; D015678:Viral Structural Proteins; D012321:DNA-Directed RNA Polymerases