title: [Etiologic structure and clinical characteristics of acute viral infections of the central nervous system with hyperproteinorachia].
abstract: Clinical syndrome of acute viral meningitis and meningoencephalitis may be induced by different viruses. Etiologic diagnosis may be set by the isolation of the virus from the liquor and by the detection of specific antibodies in the blood and liquor. Our aim was to determine viral etiology of AVI with special reference to hyperproteinorachia. The study was conducted in 55 patients treated at the Clinic of Infectious Diseases in Novi Sad, with clinical picture of acute meningitis or meningoencephalitis, with pleocytosis above 50 ml in the cerebrospinal fluid. Depending on the levels of proteinorachia the patients were divided into the group with proteinorachia levels below 1g/l (34 patients) and above 1 g/l (21 patients). In the first group the most common was herpes simplex- and adenoviral etiology while in the second group most frequently found were choriolymphocytic meningitis virus (LCM) and herpes simplex virus. The protein level was in correlation with the severity of the clinical features and the duration of the treatment.
authors.affiliation: Klinika za infektivne i dermatoveneroloske bolesti, Mediciniski fakultet, Novi Sad.
authors.forename: N
authors.initials: N
authors.lastname: Madle-Samardzija
authors.forename: J
authors.initials: J
authors.lastname: Jovanović
authors.forename: J
authors.initials: J
authors.lastname: Vukadinov
authors.forename: G
authors.initials: G
authors.lastname: Canak
authors.forename: T
authors.initials: T
authors.lastname: Preveden
authors.forename: S
authors.initials: S
authors.lastname: Brkić
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008587:Meningitis, Viral / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000382:microbiology; D014777:Virus Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis
chemical_list: D002556:Cerebrospinal Fluid Proteins
vernacular_title: Etioloska struktura i klinicke karakteristike akutnih virusnih infekcija centralnog nervnog sistema sa hiperproteinorahijom.