title: Possible virulence factors involved in bacteraemia caused by Aeromonas hydrophila.
abstract: Eighteen strains of Aeromonas hydrophila from patients with bacteraemia were investigated for possible virulence factors. Cytotoxin and haemolysin were produced by all strains, whereas cholera toxin-like factor was produced by 33% of strains only. Enterotoxin production was not detected. Haemagglutination of guinea-pig, fowl and rabbit erythrocytes was demonstrated by 83%, 67% and 61% of strains, respectively. Fucose- and mannose-sensitive haemagglutinins were predominant. None of the strains agglutinated sheep erythrocytes. Extrachromosomal DNA was detected in 17 strains, 16 of which had a plasmid (3.6-5.1 MDa), the majority being between 4.6 and 5.1 MDa.
authors.affiliation: Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: J
authors.initials: J
authors.lastname: Vadivelu
authors.forename: S D
authors.initials: SD
authors.lastname: Puthucheary
authors.forename: M
authors.initials: M
authors.lastname: Phipps
authors.forename: Y W
authors.initials: YW
authors.lastname: Chee
mesh_terms: D000293:Adolescent; D000328:Adult; D016980:Aeromonas hydrophila / Q000235:genetics / Q000472:pathogenicity*; D017677:Age Distribution; D000368:Aged; D000818:Animals; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology*; D002522:Chlorocebus aethiops; D003603:Cytotoxins / Q000096:biosynthesis; D004768:Enterotoxins / Q000096:biosynthesis; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology / Q000382:microbiology*; D006168:Guinea Pigs; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D010957:Plasmids; D011200:Poultry; D011817:Rabbits; D012189:Retrospective Studies; D017678:Sex Distribution; D012756:Sheep; D014709:Vero Cells; D014774:Virulence / Q000235:genetics
chemical_list: D003603:Cytotoxins; D004768:Enterotoxins