Identification of a Bacillus subtilis spo0H allele that is necessary for suppression of the sporulation-defective phenotype of a spo0A mutation.
A mutation in Bacillus subtilis spo0A codon 97 suppressed the sporulation defect caused by the spo0A9V mutation. The suppressor activity of the codon 97 mutation was evident only in the presence of a novel spo0H allele. Our results suggest that the spo0A gene product interacts with the sigma factor subunit of RNA polymerase.
Bramucci
M G
MG
Department of Microbiology and Immunology, Hahnemann University, Philadelphia, Pennsylvania 19102.
Green
B D
BD
Ambulos
N
N
Youngman
P
P
D000483:Alleles; D000595:Amino Acid Sequence; D001412:Bacillus subtilis / Q000235:genetics* / Q000254:growth & development; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D008969:Molecular Sequence Data; D010641:Phenotype; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D013171:Spores, Bacterial / Q000235:genetics / Q000254:growth & development*; D013489:Suppression, Genetic; D014157:Transcription Factors / Q000235:genetics*
D001426:Bacterial Proteins; C080950:Spo0A protein, Bacillus subtilis; C087737:Spo0H protein, Bacillus subtilis; D014157:Transcription Factors