Laryngeal leishmaniasis.
A patient suffering from persistent hoarseness was eventually shown to have laryngeal leishmaniasis. The incubation period for the disease must have been at least 16 years, following infection in Southern Europe. Mucosal leishmaniasis is rare in the Eastern hemisphere, and laryngeal leishmaniasis has not previously been reported in the UK. Previous Mediterranean cases have run a similar chronic course and have caused diagnostic difficulty, in particular being mistaken for malignancy. Treatment with aminosidine was ineffective, but the patient responded to liposomal amphotericin.
Grant
A
A
Hospital for Tropical Diseases, London.
Spraggs
P D
PD
Grant
H R
HR
Bryceson
A D
AD
D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology*; D007830:Larynx / Q000469:parasitology; D007896:Leishmaniasis / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology*; D008875:Middle Aged; D009092:Mucous Membrane / Q000469:parasitology; D013997:Time Factors
D000666:Amphotericin B