Mechanism of leflunomide-induced prevention of xenoantibody formation and xenograft rejection in the hamster to rat heart transplantation model.
Lin
Y
Y
Laboratory for Experimental Transplantation, University of Leuven, Belgium.
Sobis
H
H
Vandeputte
M
M
Waer
M
M
D000818:Animals; D000910:Antibodies, Heterophile / Q000096:biosynthesis*; D000917:Antibody Formation / Q000187:drug effects; D003165:Complement System Proteins / Q000276:immunology; D006224:Cricetinae; D016572:Cyclosporine / Q000627:therapeutic use; D003602:Cytotoxicity, Immunologic; D005434:Flow Cytometry; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control*; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D016027:Heart Transplantation / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007555:Isoxazoles / Q000494:pharmacology*; D000077339:Leflunomide; D008297:Male; D008647:Mesocricetus; D051381:Rats; D011919:Rats, Inbred Strains; D011923:Rats, Nude; D014183:Transplantation, Heterologous / Q000276:immunology*
D000910:Antibodies, Heterophile; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D016572:Cyclosporine; D003165:Complement System Proteins; D000077339:Leflunomide