[Senegalese pharmacopoeia: study of acute toxicity and antitussive activity of Calotropis procera AIT (Asclepiadaceae)].
We confirmed the innocuity of different extracts (leaves and stem bark) of Calotropis procera (Asclepiadaceae), a plant widely used in Asian and West African traditional therapy in dermatological and bronchal affections. We proved the against cough activity of the aqueous stem bark extract after administration, per os, upon bronchal irritation by ammoniac on Guinea Pig.
Dieye
A M
AM
Laboratoire de Pharmacologie et de Pharmacodynamie, Université Cheikh Anta DIOP de Dakar, Sénégal.
Tidjani
M A
MA
Diouf
A
A
Bassene
E
E
Faye
B
B
D000818:Animals; D003371:Cough / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006168:Guinea Pigs; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000627:therapeutic use / Q000633:toxicity; D010946:Plants, Medicinal; D012675:Senegal
D010936:Plant Extracts
Pharmacopée sénégalaise: etude de la toxicité aigue et de l'activité antitussive de Calotropis procera AIT (Asclepiadaceae).