title: [Isochromanylpencillins].
abstract: (R/S)-Isochroman-1-carboxylic acid (1) is resolved to its enantiomers and as well as these reacted with 6-aminopenicillanic acid to the title compounds 2. The activity of the new penicillin-derivatives against gram positive and gram negative bacteria is compared with that of benzyl penicillin.
authors.affiliation: Institut für Pharmazeutische Chemie, Westfälischen Wilhelms-Universität, Münster.
authors.forename: B
authors.initials: B
authors.lastname: Unterhalt
authors.forename: B
authors.initials: B
authors.lastname: Krebs
authors.forename: M
authors.initials: M
authors.lastname: Läge
authors.forename: B
authors.initials: B
authors.lastname: Nocon
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D010406:Penicillins
vernacular_title: Isochromanylpenicilline.