Simian AIDS type D serogroup 2 retrovirus: isolation of an infectious molecular clone and sequence analyses of its envelope glycoprotein gene and 3' long terminal repeat.
We describe the molecular cloning of a serogroup 2 simian retrovirus (SRV; D2/RHE/OR) and present the sequence of its envelope (env) glycoprotein gene and 3' long terminal repeat region. This report documents the first infectious molecular clone of a serogroup 2 SRV and provides env sequence verification of genetic diversity among serogroup 2 SRV isolates.
Marracci
G H
GH
Division of Primate Medicine, Oregon Regional Primate Research Center, Oregon Health Sciences University, Beaverton 97006.
Kelley
R D
RD
Pilcher
K Y
KY
Crabtree
L
L
Shiigi
S M
SM
Avery
N
N
Leo
G
G
Webb
M C
MC
Hallick
L M
LM
Axthelm
M K
MK
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D003001:Cloning, Molecular; D004279:DNA, Viral; D015686:Gene Products, env / Q000235:genetics*; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D015301:Retroviruses, Simian / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity / Q000502:physiology; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D012703:Serotyping; D016097:Simian Acquired Immunodeficiency Syndrome / Q000821:virology*; D014162:Transfection; D014774:Virulence / Q000235:genetics
D004279:DNA, Viral; D015686:Gene Products, env