Searching for the phenotypes of schizophrenia.
Use of clinical diagnosis as the phenotype for genetic study is discussed, and criteria for appropriate alternative phenotypes are presented. Then, recent research on four alternatives is discussed: (a) resistance to interference from an associative prime, (b) reaction time crossover, (c) creativity, and (d) socioeconomic achievement. It is concluded that resistance to interference from an associative prime and reaction time crossover at 3-sec. preparatory interval level are the most promising of these candidates.
Cromwell
R L
RL
University of Kansas, Lawrence 66045-2462.
Elkins
I J
IJ
McCarthy
M E
ME
O'Neil
T S
TS
D003405:Creativity; D006801:Humans; D010641:Phenotype; D011930:Reaction Time; D012559:Schizophrenia / Q000235:genetics*; D012959:Socioeconomic Factors