[Holt-Oram syndrome. Review and report of 2 familial cases].
In 1960 Holt and Oram reported a family in which upper extremity malformations were associated with a secundum atrial septal defect. Since then, more than 200 cases have been reported with a wide spectrum of phenotypes. The authors present the cases of one mother and daughter with Holt-Oram Syndrome (SHO).
Oliveira
M
M
Serviço de Cardiologia, Hospital de Santa Marta, Lisboa.
Agapito
A
A
Rosário
L
L
Galrinho
A
A
da Silva
N
N
Prates
A
A
Antunes
A M
AM
D000328:Adult; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D013577:Syndrome
Síndrome de Holt-Oram. Revisão a propósito de 2 casos clínicos numa família.