[Undifferentiated carcinoma of cervical node metastases in patients with an unknown primary lesion: an immunohistochemical study].
Sixteen patients with lymphatic metastases to the neck and a histological diagnosis of undifferentiated carcinoma from an unknown primary lesion were assessed using immunohistochemical staining. The results revealed a non-epithelial tumor in 11 cases (malignant lymphoma in 5 cases) and an epithelial tumor in 3 cases. The patients with malignant lymphoma had a good outcome, but those with other non-epithelial tumors did not. Treatment of patients with an unknown primary tumor, especially undifferentiated carcinoma, should be carefully evaluated based on immunohistological examinations to identify malignant lymphoma.
Nakamizo
M
M
Head and Neck Division, Cancer Institute Hospital, Tokyo.
Kamata
S E
SE
Kawabata
K
K
Takahashi
H
H
Nigauri
T
T
Hoki
K
K
Yanagisawa
A
A
D000230:Adenocarcinoma / Q000556:secondary*; D014408:Biomarkers, Tumor / Q000097:blood; D002277:Carcinoma / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000473:pathology; D009333:Neck; D009382:Neoplasms, Unknown Primary / Q000473:pathology*
D014408:Biomarkers, Tumor