title: Tc-99m sulfur colloid demonstration of diffuse pulmonary interstitial extramedullary hematopoiesis in a patient with myelofibrosis. A case report and review of the literature.
abstract: A 60-year-old man with a myeloproliferative syndrome and extramedullary hematopoiesis had progressive respiratory and cardiac insufficiency during the previous 18 months, with advancing interstitial pulmonary disease on chest x-ray. During analysis of his respiratory disease, results of a transbronchial biopsy showed interstitial involvement with increased numbers of megakaryocytes and other panhematopoietic staining elements. Results of a bone marrow scan demonstrated diffuse replacement of pulmonary interstitium with bone marrow, as a component of known ongoing extramedullary hematopoiesis.
authors.affiliation: Department of Radiology, Virginia Mason Medical Center, Seattle, Washington.
authors.forename: G G
authors.initials: GG
authors.lastname: Coates
authors.forename: B
authors.initials: B
authors.lastname: Eisenberg
authors.forename: D H
authors.initials: DH
authors.lastname: Dail
mesh_terms: D001853:Bone Marrow / Q000000981:diagnostic imaging; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011877:Radionuclide Imaging; D013671:Technetium Tc 99m Sulfur Colloid
chemical_list: D013671:Technetium Tc 99m Sulfur Colloid