Bone marrow transplantation for erythroleukemia: a case report.
A 2 year old girl was diagnosed as having erythroleukemia (EL; M6 according to the French-American-British classification). After one course of low-dose cytosine arabinoside (Ara-C), complete remission was obtained. After three courses of low-dose Ara-C for consolidation, allogeneic bone marrow transplantation was performed from HLA-identical sibling. The course of post-transplantation was uneventful. Two years after transplantation, she continues to have durable engraftment and remission. In children with EL, conventional chemotherapy appears to be inadequate for producing durable long-term disease-free survival. Bone marrow transplantation should be considered in children with EL, in cases where suitable donors are available.
Kogawa
K
K
Department of Pediatrics, National Defense Medical College, Saitama, Japan.
Sekine
I
I
Masuda
T
T
Takada
Y
Y
Yoshioka
S
S
Hirota
T
T
Eguchi
M
M
D016026:Bone Marrow Transplantation; D002675:Child, Preschool; D003561:Cytarabine / Q000008:administration & dosage / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007621:Karyotyping; D004915:Leukemia, Erythroblastic, Acute / Q000188:drug therapy / Q000601:surgery*; D016896:Treatment Outcome
D003561:Cytarabine