Microangiopathic hemolytic anemia and renal impairment following autologous bone marrow transplantation: a case of hemolytic uremic syndrome?
Thrombotic microangiopathy, which encompasses both thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), is a severe and life-threatening complication following bone marrow transplantation (BMT). It has been reported after allogeneic BMT but may also occur after autologous BMT. Here we describe a case of microangiopathic hemolytic anemia and progressive renal failure subsequent to autologous BMT.
Wassmann
B
B
Department of Hematology, Johann Wolfgang Goethe-University, Frankfurt/Main, Germany.
Martin
H
H
Elsner
S
S
Bruecher
J
J
Thaiss
F
F
Stahl
R A
RA
Hoelzer
D
D
D000743:Anemia, Hemolytic / Q000209:etiology*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology*; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000209:etiology; D012307:Risk Factors; D013997:Time Factors; D014182:Transplantation, Autologous
D003404:Creatinine