Development of the cell-division site in FtsA- filaments.
Early changes at cell-division sites were studied in non-septate filaments induced by growth of ftsATs mutant cells under non-permissive conditions. The positions of localized regions of plasmolysis were used as markers for the locations of partial and complete annular structures that are thought to be precursors of the periseptal annuli that flank the septum during cytokinesis. The results confirmed that these structures were localized at potential division sites and suggested a model in which older division sites play a role in the generation of new sites for future use, with each older site being used only once for this purpose. The results also suggest that the details of division-site development can profitably be studied in cells in which early events in the differentiation process are uncoupled from the septation event.
Cook
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Department of Microbiology, University of Connecticut Health Center, Farmington 06032.
Rothfield
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D001422:Bacterial Adhesion / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D002455:Cell Division / Q000235:genetics; D003599:Cytoskeleton / Q000235:genetics; D004926:Escherichia coli / Q000166:cytology* / Q000235:genetics / Q000254:growth & development; D029968:Escherichia coli Proteins; D005798:Genes, Bacterial; D008954:Models, Biological; D009154:Mutation; D013696:Temperature
D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; C065103:FtsA protein, Bacteria; C489310:FtsA protein, E coli