title: Arterial thrombosis in the nephrotic syndrome.
abstract: Thrombosis is a frequent cause of morbidity and mortality in patients with the nephrotic syndrome. Venous thrombotic complications are well recognized but arterial complications are rare. Thrombosis is multifactorial, and has been attributed to a hypercoaguable state due to alterations in blood levels of the various factors involved in the coagulation and fibrinolytic systems, alterations in platelet function, venous stasis, haemoconcentration, increased blood viscosity and possibly the administration of steroids. Thrombosis in general and arterial thrombosis in particular is a significant and potentially serious problem in nephrotic patients. Awareness of the condition and its pathogenesis is needed. Assessment for the risk factors is required to allow appropriate prophylactic measures to be taken.
authors.affiliation: Regional Renal Unit, Royal Liverpool University Hospital, UK.
authors.forename: I H
authors.initials: IH
authors.lastname: Fahal
authors.forename: P
authors.initials: P
authors.lastname: McClelland
authors.forename: C R
authors.initials: CR
authors.lastname: Hay
authors.forename: G M
authors.initials: GM
authors.lastname: Bell
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000150:complications*; D012307:Risk Factors; D013927:Thrombosis / Q000150:complications* / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control