[Analysis of DNA polymorphism detected by genomic fingerprinting based on phage M13 DNA, in populations of Bashkir and Komi].
Hyperpolymorphism of minisatellite DNA, detected using the M13 bacteriophage DNA hybridization probe, was studied in three ethnographic groups of Bashkirs and in the Komi population. Bands from 2 to 20 kb were analyzed in hybridization patterns. A significant population difference was detected both in evaluation of the average number of hybridization fragments per individuals and in the distribution of frequency of some fractions. Thus, it seems possible to describe a set of so-called characteristic fractions for each population. According to the hybridization fragment frequency for the populations investigated, an index of genetic similarity was calculated. The possibility of using this kind of multiple polymorphism of DNA in population genetic investigations at the level of ethnic groups and peoples is discussed, and a conclusion is made about the necessity of searching for the most informative methods of analyzing the data obtained.
Khusnutdinova
E K
EK
Khidiiatova
I M
IM
Prosniak
M I
MI
Rafikov
Kh S
KhS
Limborskaia
S A
SA
D017104:Bacteriophage M13 / Q000235:genetics*; D016172:DNA Fingerprinting; D015342:DNA Probes; D004276:DNA, Satellite / Q000235:genetics*; D004279:DNA, Viral / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D009693:Nucleic Acid Hybridization; D011110:Polymorphism, Genetic; D012426:Russia
D015342:DNA Probes; D004276:DNA, Satellite; D004279:DNA, Viral; D005819:Genetic Markers
Analiz polimorfizma DNK, vyiavliaemogo metodom genomnoĭ daktiloskopii na osnove DNK faga M13, v populiatsiiakh Bashkir i Komi.