ABH and Lewis immunohistochemistry of the human eye.
ABH and Lewis antigens are detected by immunohistochemistry exclusively in the anterior cornea epithelium and in the conjunctiva bulbi, but not in the ciliary body, in the retina, or in the vitreous body of the eye. The ABH antigens found in the vitreous humor by the absorption elution technique (Rordorf et al., Forensic Sci. Int. 41, 1989, 111-116) are probably glycosphingolipids, which are not detected by immunohistochemistry. They may come from the plasma of uveal blood vessels, or be produced by local cells.
Pedal
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University of Heidelberg, Institute of Forensic Medicine, Germany.
Wetzel
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C
Min
J X
JX
Daus
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D000017:ABO Blood-Group System / Q000032:analysis*; D003228:Conjunctiva / Q000473:pathology; D003315:Cornea / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D005123:Eye / Q000473:pathology*; D006801:Humans; D007983:Lewis Blood Group Antigens / Q000032:analysis*; D014822:Vitreous Body / Q000473:pathology
D000017:ABO Blood-Group System; D007983:Lewis Blood Group Antigens