title: Principles of CDK regulation.
abstract: As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.
authors.affiliation: Department of Physiology, University of California, San Francisco 94143-0444.
authors.forename: D O
authors.initials: DO
authors.lastname: Morgan
mesh_terms: D000818:Animals; D002384:Catalysis; D002453:Cell Cycle / Q000502:physiology; D018844:Cyclin-Dependent Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D016213:Cyclins / Q000378:metabolism; D010766:Phosphorylation
chemical_list: D016213:Cyclins; D018844:Cyclin-Dependent Kinases