title: Evaluation of an automated spectrophotometric assay for the determination of total sialic acid in canine serum.
abstract: This study validates an automated enzymatic assay using the Cobas Fara (Roche) centrifugal analyser, which offers a reliable measurement of the total sialic acid concentration in canine serum as assessed by evaluating the precision and accuracy. Data are presented on the biological variation in the total serum sialic acid concentration. Measurements of total serum sialic acid concentration appear to be useful in distinguishing dogs with neoplastic disorders from clinically healthy dogs.
authors.affiliation: Central Laboratory, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
authors.forename: A V
authors.initials: AV
authors.lastname: Thougaard
authors.forename: A L
authors.initials: AL
authors.lastname: Jensen
authors.forename: A
authors.initials: A
authors.lastname: Wenck
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D004283:Dog Diseases / Q000097:blood*; D004285:Dogs; D005260:Female; D008297:Male; D019158:N-Acetylneuraminic Acid; D009369:Neoplasms / Q000097:blood / Q000662:veterinary*; D015203:Reproducibility of Results; D012794:Sialic Acids / Q000097:blood*; D013053:Spectrophotometry / Q000662:veterinary*
chemical_list: D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid