[The importance of examining genetic polymorphism of drug oxidation in psychiatry].
The paper describes: 1. Drug oxidation process. 2. Cytochrome P-450 Isozymes. 3. Genetic polimorphism of drug oxidation. 4. Spartein test. Metabolic ratio, extensive and poor metabolizers. 5. Cytochrom P-450 and drug metabolism. 6. Inhibition of drug oxidation process and inhibitors of CYP450. 7. Influence of CYP450 genetic polimorphism on development of diseases. 8. Clinical value of examining the genetic polimorphism of drug oxidation in psychiatry.
Beszłej
J A
JA
Katedry i Kliniki Psychiatrii AM we Wrocławiu.
Kiejna
A
A
D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D007527:Isoenzymes; D008099:Liver / Q000201:enzymology; D008617:Mephenytoin / Q000378:metabolism; D008659:Metabolic Diseases / Q000175:diagnosis; D010084:Oxidation-Reduction; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D011570:Psychiatry; D013034:Sparteine / Q000378:metabolism
D007527:Isoenzymes; D013034:Sparteine; D003577:Cytochrome P-450 Enzyme System; D008617:Mephenytoin
Znaczenie dla psychiatrii badania genetycznego polimorfizmu utleniania leków.