title: Tuberculosis: pathogenesis and laboratory diagnosis.
abstract: Emerging molecular biologic technologies hold the promise of more rapid diagnosis of tuberculosis and more definitive epidemiologic linkages of cases of TB. In addition to reviewing the pathogenesis of tuberculosis, this chapter covers a variety of methods for the rapid detection of the disease, including the acid-fast smear, conventional culture, the BACTEC system, immunodiagnostic methods, and DNA-based techniques.
authors.affiliation: Department of Medicine, Columbia College of Physicians and Surgeons, New York, NY.
authors.forename: J G
authors.initials: JG
authors.lastname: Ford
authors.forename: C P
authors.initials: CP
authors.lastname: Felton
mesh_terms: D019411:Clinical Laboratory Techniques; D015658:HIV Infections / Q000150:complications; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification* / Q000472:pathogenicity*; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology