Acrodermatitis chronica atrophicans involving the face. Evidence for Borrelia burgdorferi infection confirmed by DNA amplification.
In a female patient with increasing redness of the hands and face, proteins of Borrelia burgdorferi were detected in a biopsy of the ear by DNA amplification. Although acrodermatitis chronica atrophicans has been documented to be caused by B. burgdorferi, this is the first case with proven spirochetal presence in the skin of the head. After 2 weeks of intravenous therapy with ceftriaxone marked improvement of discoloration of the skin was noted.
Müller
D E
DE
Department of Dermatology, University of Basel, Switzerland.
Itin
P H
PH
Büchner
S A
SA
Rufli
T
T
D000169:Acrodermatitis / Q000382:microbiology* / Q000473:pathology*; D000368:Aged; D001284:Atrophy; D015748:Borrelia burgdorferi Group / Q000235:genetics / Q000302:isolation & purification; D002908:Chronic Disease; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D005148:Facial Dermatoses / Q000382:microbiology* / Q000473:pathology*; D005260:Female; D005784:Gene Amplification; D006229:Hand Dermatoses / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008193:Lyme Disease / Q000382:microbiology / Q000473:pathology*
D004269:DNA, Bacterial