Evaluation of a new direct radioimmunoassay for serum thyroid peroxidase and thyroglobulin antibodies.
The measurement of serum TPO Ab and Tg Ab by a new direct sensitive RIA in this study are quantitative and provided a convenient system. When compared to the commonly used PH technique for TM Ab and Tg Ab, this RIA determination appears to be more sensitive than by PH, since it enabled detection of TPO Ab and/or Tg Ab in sera that were negative by PH. Thus, this RIA determination should be more widely used in a clinical laboratory.
Chailurkit
L O
LO
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Rajatanavin
R
R
Teerarungsikul
K
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000378:metabolism*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007453:Iodide Peroxidase / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay / Q000379:methods*; D013954:Thyroglobulin / Q000276:immunology*; D013959:Thyroid Diseases / Q000378:metabolism*
D001323:Autoantibodies; D013954:Thyroglobulin; D007453:Iodide Peroxidase