title: Early onset of cecal perforation in neonatal, recto-sigmoid type Hirschsprung's disease.
abstract: Hirschsprung's disease has been considered to cause intestinal perforation in rare cases. Even if a perforation occurs, the majority of cases are associated with the long-segment or total colonic type. Our case developed the perforation in the neonatal period in spite of being of the recto-sigmoidal type, and it affected the cecum. We do not have a good explanation for this condition. However, the pathological examination of the specimens of the perforated cecum revealed some necrosis (ulceration, subcutaneous hemorrhage, congestion and severe edema) which was considered to be caused by ischemia, secondary to a localized vascular accident in the wall of the distended intestine.
authors.affiliation: Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Hayashi
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Tahara
authors.forename: K
authors.initials: K
authors.lastname: Fujisawa
authors.forename: Y
authors.initials: Y
authors.lastname: Eto
authors.forename: Y
authors.initials: Y
authors.lastname: Yamazaki
authors.forename: K
authors.initials: K
authors.lastname: Maekawa
mesh_terms: D017668:Age of Onset; D006627:Hirschsprung Disease / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D007416:Intestinal Perforation / Q000175:diagnosis / Q000209:etiology*; D007813:Laparotomy; D008297:Male