Enhancement of platelet aggregation in patients with nasopharyngeal carcinoma.
The ADP-induced platelet aggregation in 157 patients with nasopharyngeal carcinoma (NPC) in South China was estimated. The difference between the maximum platelet aggregation rate (MAR) in the control group and the MAR of patients with stage III/IV was significant. That is, the MAR at stage III and stage IV was significantly enhanced, as compared to that in the control group and that at stage I or stage II. The results of the present study indicate that ADP-induced platelet aggregation is enhanced in NPC patients of stage III and stage IV.
Huang
G W
GW
Department of Otorhinolaryngology, Guangxi Medical College, Nanning, China.
Nong
H T
HT
Nakamura
M
M
Kosugi
T
T
D000244:Adenosine Diphosphate / Q000494:pharmacology* / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D005260:Female; D005340:Fibrinogen / Q000187:drug effects; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D009305:Nasopharynx / Q000473:pathology*; D009367:Neoplasm Staging; D010974:Platelet Aggregation / Q000187:drug effects*; D010976:Platelet Count; D016896:Treatment Outcome
D000244:Adenosine Diphosphate; D005340:Fibrinogen