title: Early cardiorespiratory patterns in patients with major burns and pulmonary insufficiency.
abstract: We examined the case records of 50 consecutive patients with major cutaneous burns who required early mechanical ventilation. In 22 patients full haemodynamic and respiratory data were available within 24 h of their injury. Unexpectedly the haemodynamic and oxygen transport patterns of survivors and non-survivors were essentially similar although pulmonary artery occlusion pressure measurements and estimations of net fluid input suggest that non-survivors were relatively underresuscitated compared with survivors. Both groups showed inadequate oxygen utilization in the early stages of their injury despite normal (or above normal) levels of oxygen delivery. Invasive monitoring could possibly help this subgroup of burns patients.
authors.affiliation: Burns Unit, University Hospital of South Manchester, UK.
authors.forename: J G
authors.initials: JG
authors.lastname: Miller
authors.forename: P
authors.initials: P
authors.lastname: Bunting
authors.forename: D A
authors.initials: DA
authors.lastname: Burd
authors.forename: J D
authors.initials: JD
authors.lastname: Edwards
mesh_terms: D000328:Adult; D002056:Burns / Q000150:complications* / Q000401:mortality / Q000628:therapy; D005260:Female; D006331:Heart Diseases / Q000209:etiology* / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D010101:Oxygen Consumption; D011379:Prognosis; D012121:Respiration, Artificial; D015208:Smoke Inhalation Injury / Q000150:complications* / Q000401:mortality / Q000628:therapy; D016019:Survival Analysis