title: Treatment of idiopathic renal magnesium wasting with amiloride.
abstract: We report a case of an 18-year-old female who presented with severe hypomagnesmia due to idiopathic renal magnesium wasting. Only a partial response was noted with magnesium oxide replacement. Treatment with the potassium-sparing diuretic amiloride led to a further rise in the serum magnesium level, a decrease in the fractional excretion of magnesium and improvement in her symptoms. This case demonstrates an effective treatment for idiopathic renal magnesium wasting.
authors.affiliation: Division of Nephrology, Naval Medical Center, Portsmouth, VA 23708.
authors.forename: J T
authors.initials: JT
authors.lastname: Bundy
authors.forename: D
authors.initials: D
authors.lastname: Connito
authors.forename: M D
authors.initials: MD
authors.lastname: Mahoney
authors.forename: P J
authors.initials: PJ
authors.lastname: Pontier
mesh_terms: D000293:Adolescent; D000584:Amiloride / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism; D008274:Magnesium / Q000097:blood* / Q000378:metabolism; D015499:Renal Tubular Transport, Inborn Errors / Q000150:complications / Q000188:drug therapy*; D014883:Water-Electrolyte Imbalance / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000584:Amiloride; D008274:Magnesium