Subtype analysis of hepatitis C virus in Indonesia on the basis of NS5b region sequences.
A recently identified subtype of hepatitis C virus, subtype 1d, was found to be common in Indonesia, being isolated from 4 (20%) of 20 and 11 (34%) of 32 patients with chronic hepatitis and liver cirrhosis, respectively. A new group of sequence variants was also identified, although its prevalence ratio was not as high in the area surveyed.
Hotta
H
H
Department of Microbiology, Kobe University School of Medicine, Hyogo, Japan.
Handajani
R
R
Lusida
M I
MI
Soemarto
W
W
Doi
H
H
Miyajima
H
H
Homma
M
M
D001483:Base Sequence; D004279:DNA, Viral / Q000032:analysis; D016174:Hepacivirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006526:Hepatitis C / Q000453:epidemiology / Q000821:virology*; D006521:Hepatitis, Chronic / Q000821:virology; D006801:Humans; D007214:Indonesia / Q000453:epidemiology; D008103:Liver Cirrhosis / Q000821:virology; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D015995:Prevalence
D004279:DNA, Viral