Azathioprine myelotoxicity related to elevated 6-thioguanine nucleotides in heart transplantation.
Schütz
E
E
Department of Clinical Chemistry, Georg August University, Göttingen, Germany.
Gummert
J
J
Mohr
F W
FW
Armstrong
V W
VW
Oellerich
M
M
D000328:Adult; D000368:Aged; D001379:Azathioprine / Q000627:therapeutic use / Q000633:toxicity*; D016572:Cyclosporine / Q000097:blood / Q000627:therapeutic use; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D005260:Female; D016027:Heart Transplantation / Q000276:immunology / Q000502:physiology*; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects; D007970:Leukopenia / Q000097:blood / Q000139:chemically induced*; D008297:Male; D008780:Methyltransferases / Q000097:blood* / Q000172:deficiency; D008875:Middle Aged; D012016:Reference Values; D013866:Thioguanine / Q000097:blood*
D016572:Cyclosporine; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D013866:Thioguanine; D001379:Azathioprine