Oral administration of quercitrin modifies intestinal oxidative status in rats.
1. Oral administration of quercitrin to rats for 3 days increases the mucosal glutathione contents in ileum and colon as well as inhibits non-enzymatic lipid peroxidation induced in membrane fractions from jejunal and colonic mucosa. 2. After 7 days of treatment with quercitrin, rat intestinal oxidative status trends to normalize to control rats.
Galvez
J
J
Department of Pharmacology, School of Pharmacy, Universidad de Granada, Spain.
de la Cruz
J P
JP
Zarzuelo
A
A
Sanchez de Medina
F
F
Jimenez
J
J
Sanchez de la Cuesta
F
F
D000284:Administration, Oral; D000818:Animals; D005260:Female; D005978:Glutathione / Q000378:metabolism*; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects*; D011794:Quercetin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
C012526:quercitrin; D011794:Quercetin; D005978:Glutathione