title: A computer model for simulating ultrasonic scattering in biological tissues with high scatterer concentration.
abstract: Scattering of ultrasonic waves by biological tissues at different scatterer concentrations is investigated using one- and two-dimensional computer simulation models. The backscattered power as a function of scatterer concentrations is calculated using two types of incident waves, a Gaussian shaped pulse and a continuous wave (CW). The simulation results are in good agreement with the Percus-Yevick packing theory within the scatterer concentrations, from 0% to 100% in one-dimensional (1D) space, and 0% to 46% in two-dimensional (2D) space. In all cases, the simulation results from a pulsed incident wave show a much smaller standard deviation (SD) than those from an incident CW. The simulation can serve as a useful tool to verify scattering theories, simulate different experimental conditions, and to investigate the interaction between the scatterer properties and the scattering of ultrasonic waves. More importantly, the 2D simulation procedure serves as an initial step toward the final realization of a true three-dimensional (3D) simulation of ultrasonic scattering in biological tissues.
authors.affiliation: Department of Engineering Science and Mechanics, Pennsylvania State University, University Park 16802.
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: J L
authors.initials: JL
authors.lastname: Rose
authors.forename: K K
authors.initials: KK
authors.lastname: Shung
mesh_terms: D001769:Blood; D003198:Computer Simulation; D006400:Hematocrit; D006801:Humans; D014465:Ultrasonics