[Endolymphatic chemotherapy and immunocorrection in patients with kidney and bladder cancers].
Immunological examination and endolymphatic treatment were performed in 44 patients with cancer of the kidney or urinary bladder. In the majority of patients lymphocytes of the peripheral blood demonstrated reduced expression of some differential antigens. Subpopulation of T-lymphocytes, expression of T-lymphocyte receptors got decreased in almost all the patients. Endolymphatic introduction of immunocorrective thymalin improved the patients' life quality, their immune status. However, the level and proportional expression of differential lymphocyte antigens following course polychemotherapy and immunocorrection in patients do not coincide with relevant parameters of healthy subjects. It is evident that further search for optimal treatment schemes is needed.
Serniak
P S
PS
Geev
Iu V
IuV
Prilutskiĭ
A S
AS
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D015703:Antigens, CD / Q000097:blood / Q000187:drug effects; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006801:Humans; D007111:Immunity, Cellular; D007272:Injections, Intralymphatic; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000276:immunology; D013951:Thymus Hormones / Q000008:administration & dosage*; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000276:immunology
D000276:Adjuvants, Immunologic; D015703:Antigens, CD; D013951:Thymus Hormones; C032805:thymalin
Endolimfaticheskaia khimioterapiia i immunokorrektsiia u bol'nykh rakom pochki i mochevogo puzyria.