[Direct approach for demonstrating free radical phenomena during equine postanesthetic myopathy: preliminary study].
This preliminary study demonstrated the existence of a free radical generation during an experimental postischemic muscular reperfusion in a halothane anesthetized horse. The authors used alpha-phényl-N-tert-butylnitrone as a spin trap agent and the electronic paramagnetic resonance method to observe in vivo a free radical generation.
Serteyn
D
D
Service de chirurgie des grands animaux et d'anesthésiologie, Faculté de médecine vétérinaire, Université de Liège, Belgique.
Pincemail
J
J
Mottart
E
E
Caudron
I
I
Deby
C
C
Deby-Dupont
G
G
Philippart
C
C
Lamy
M
M
D000769:Anesthesia, Inhalation / Q000009:adverse effects / Q000662:veterinary*; D000818:Animals; D003497:Cyclic N-Oxides; D005260:Female; D005609:Free Radicals / Q000378:metabolism*; D006221:Halothane / Q000009:adverse effects; D006734:Horse Diseases / Q000209:etiology / Q000378:metabolism*; D006736:Horses; D009135:Muscular Diseases / Q000378:metabolism / Q000662:veterinary*; D009589:Nitrogen Oxides; D015427:Reperfusion Injury / Q000378:metabolism / Q000662:veterinary*; D013113:Spin Labels
D003497:Cyclic N-Oxides; D005609:Free Radicals; D009589:Nitrogen Oxides; D013113:Spin Labels; C029217:phenyl-N-tert-butylnitrone; D006221:Halothane
Approche directe pour la mise en évidence des phénomènes radicalaires lors de myopathie postanesthésique équine: étude préliminaire.