title: [Surgical therapy for local recurrence and distant metastasis of lung cancer].
abstract: Twenty-two patients underwent surgical therapy for local recurrence and distant metastasis of lung cancer. Twenty patients were resected the tumor and 2 patients received the operation to improve their quality of life. Seven patients were resected lung metastasis, which were 5 adenocarcinomas and 2 squamous cell carcinomas. All metastasis situated in contralateral lung of primary operation. Two lobectomies, 1 segmentectomy, and 4 partial resections were performed. The 5-year survival rate was 28.6%. Four patients were resected brain metastasis, which were 2 adeno-squamous cell carcinomas, 1 squamous cell carcinoma, and 1 large cell carcinoma. The 5-year survival rate was 25%. Three patients were resected the neck and upper mediastinal lymph node metastasis. Since those lymph nodes could not be dissected at the initial operation, different approaches, which was median sternotomy and collar incision of neck, were selected. Two patients were alive 5 months after operation. There were no long-term survivors in 5 patients with bone or soft tissue metastasis. Since the differentiation of lung metastasis from the second primary tumor is impossible, the single lung metastasis should be resected. Resection of single brain metastasis provides better prognosis.
authors.affiliation: Second Department of Surgery, Nagoya City University, Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Niwa
authors.forename: A
authors.initials: A
authors.lastname: Masaoka
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary*; D001932:Brain Neoplasms / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D011013:Pneumonectomy; D011788:Quality of Life