Donor-specific transplantation unresponsiveness in sensitized rats following treatment with a nondepleting anti-CD4 MAb is associated with selective intragraft sparing of Th2-like cells.
Binder
J
J
Department of Surgery, Harvard Medical School, Boston, MA 02115.
Hancock
W W
WW
Wasowska
B
B
Gallon
L
L
Watschinger
B
B
Sayegh
M H
MH
Brock
J
J
Lehmann
M
M
Volk
H D
HD
Kupiec-Weglinski
J W
JW
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D015704:CD4 Antigens / Q000096:biosynthesis / Q000276:immunology*; D002478:Cells, Cultured; D005434:Flow Cytometry; D016027:Heart Transplantation / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007959:Lymphocyte Culture Test, Mixed; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D014184:Transplantation, Homologous
D000911:Antibodies, Monoclonal; D015704:CD4 Antigens; D007166:Immunosuppressive Agents