title: [Holt-Oram syndrome. Review and report of 2 familial cases].
abstract: In 1960 Holt and Oram reported a family in which upper extremity malformations were associated with a secundum atrial septal defect. Since then, more than 200 cases have been reported with a wide spectrum of phenotypes. The authors present the cases of one mother and daughter with Holt-Oram Syndrome (SHO).
authors.affiliation: Serviço de Cardiologia, Hospital de Santa Marta, Lisboa.
authors.forename: M
authors.initials: M
authors.lastname: Oliveira
authors.forename: A
authors.initials: A
authors.lastname: Agapito
authors.forename: L
authors.initials: L
authors.lastname: Rosário
authors.forename: A
authors.initials: A
authors.lastname: Galrinho
authors.forename: N
authors.initials: N
authors.lastname: da Silva
authors.forename: A
authors.initials: A
authors.lastname: Prates
authors.forename: A M
authors.initials: AM
authors.lastname: Antunes
mesh_terms: D000328:Adult; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D013577:Syndrome
vernacular_title: Síndrome de Holt-Oram. Revisão a propósito de 2 casos clínicos numa família.