title: [The heterogeneity of Streptococcus pyogenes strains isolated from clinically healthy and sick children in an organized collective].
abstract: Experiments on typed strains used as an example revealed that kinetic curves obtained in the lysis by endo-N-aretylmuramidase of virulent strains greatly differed from those obtained from nonvirulent ones: the lysis rate of M+ variants was less than that of M- variants; M- strains gave rather steep kinetic curves of lysis, while those of M+ strains were more declivous. In this study group A S. pyogenes cultures isolated from healthy and sick children in a summer camp were used. The study revealed that cultures, newly isolated from healthy and sick children, were heterogeneous with respect to the M+ and M- state of group A S. pyogenes strains, the amino acid composition of pepsin fragments of M-proteins in the cultures of streptococcus M 1 under study being also heterogeneous.
authors.forename: S A
authors.initials: SA
authors.lastname: Bitko
authors.forename: N I
authors.initials: NI
authors.lastname: Briko
authors.forename: L O
authors.initials: LO
authors.lastname: Dynga
mesh_terms: D000596:Amino Acids / Q000032:analysis; D001426:Bacterial Proteins / Q000032:analysis / Q000378:metabolism; D001433:Bacteriolysis / Q000187:drug effects; D002353:Carrier State / Q000382:microbiology*; D002473:Cell Wall / Q000378:metabolism; D002648:Child; D006026:Glycoside Hydrolases / Q000494:pharmacology; D006801:Humans; D013290:Streptococcal Infections / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000187:drug effects / Q000302:isolation & purification* / Q000378:metabolism / Q000472:pathogenicity; D014774:Virulence / Q000187:drug effects
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D006026:Glycoside Hydrolases; C026255:endo-N-acetylmuramidase
vernacular_title: Geterogennost' shtammov Streptococcus pyogenes, vydelennykh ot klinicheski zdorovykh i bol'nykh deteĭ v organizovannom kollektive.