title: Attitudes towards detection and management of hepatic metastases of colorectal origin: a second look.
abstract: In the present study we undertook an international postal survey to assess the current attitudes towards the detection and management of hepatic metastases in colorectal cancer patients, who have been operated on with curative intent. Results of this survey were compared to results of an earlier survey, held in 1985. Both surveys indicate that there is no consensus on the follow-up of patients at risk of hepatic metastases. Especially the interpretation of unexplained rises in carcinoembryonic antigen (CEA) levels leads to much controversy. Only 37% of the hospitals performing liver surgery were willing to perform second-look laparotomies based on CEA only. Also there is no agreement on the maximum number of liver metastases that will justify partial liver resection for cure. Clearly, there is a need for prospective randomized trials on which a more rational policy regarding hepatic metastases in colorectal cancer patients can be based.
authors.affiliation: Medical Decision Making Unit, University of Leiden, The Netherlands.
authors.forename: D J
authors.initials: DJ
authors.lastname: Bruinvels
authors.forename: L M
authors.initials: LM
authors.lastname: de Brauw
authors.forename: J
authors.initials: J
authors.lastname: Kievit
authors.forename: J D
authors.initials: JD
authors.lastname: Habbema
authors.forename: C J
authors.initials: CJ
authors.lastname: van de Velde
mesh_terms: D001291:Attitude of Health Personnel; D014408:Biomarkers, Tumor / Q000032:analysis; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D012086:Reoperation; D011795:Surveys and Questionnaires
chemical_list: D014408:Biomarkers, Tumor