title: Does a history of convulsions increase the amnestic effect of temporal region brain lesions?
abstract: Rats with surgical lesions of the hippocampal formation, amygdala, and nearby neocortex and pyriform cortex were impaired on a swim-to-platform test and on a passive avoidance test. These impairments were not increased by presurgical treatment with a series of 21 electroshock convulsions. To the extent that this rat preparation can be compared with human patients, the data suggest that a previous history of epileptic seizures does not increase the amnestic effect of temporal lobe lesions.
authors.affiliation: Department of Psychology, University of Western Ontario, London, Canada.
authors.forename: C H
authors.initials: CH
authors.lastname: Vanderwolf
mesh_terms: D000647:Amnesia / Q000209:etiology*; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D001522:Behavior, Animal / Q000502:physiology; D004597:Electroshock; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D051381:Rats; D013702:Temporal Lobe / Q000502:physiology*