title: Seventeen years of application of herpes vaccines in Bulgaria.
abstract: This study reports on our experience with whole herpes simplex vaccines in Bulgaria for a period of 17 years. More than 1,500 immunized patients with herpes ophtalmicus showed a reduction of the recovery period, reduced number of the recurrences and reduced risk of visual damage. More than 14,000 patients suffering from other forms of herpes diseases for a longer period showed reduced recovery period and recurrence frequency in over 95% of the cases. Whole vaccines were well tolerable with no side effects. This report emphasizes the usefulness of whole herpes vaccines.
authors.affiliation: Department of Virology, National Center of Infectious and Parasitic Diseases (NCIPD), Sofia, Bulgaria.
authors.forename: S
authors.initials: S
authors.lastname: Dundarov
authors.forename: P
authors.initials: P
authors.lastname: Andonov
mesh_terms: D000293:Adolescent; D000328:Adult; D002031:Bulgaria; D005260:Female; D006558:Herpes Genitalis / Q000276:immunology / Q000517:prevention & control / Q000628:therapy; D006560:Herpes Labialis / Q000276:immunology / Q000517:prevention & control / Q000628:therapy; D006561:Herpes Simplex / Q000276:immunology / Q000517:prevention & control* / Q000628:therapy; D006801:Humans; D016849:Keratitis, Herpetic / Q000276:immunology / Q000517:prevention & control / Q000628:therapy; D008297:Male; D012008:Recurrence; D018139:Simplexvirus / Q000276:immunology*; D013997:Time Factors; D014765:Viral Vaccines / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D014765:Viral Vaccines