title: The value of three-dimensional turbo-FLASH and spin-echo sequences in the detection of pituitary microadenomas following gadolinium administration.
abstract: Our purpose was the comparison of T1-weighted spin-echo (SE) and three-dimensional (3D) Turbo-fast low-angle shot (FLASH) (3DTFL) in detection of 14 pituitary microadenomas following intravenous gadolinium (Gd). 3DTFL represents an important improvement in the diagnosis of pituitary microadenomas. In two cases, the site of the tumour was correctly identified only by Gd-enhanced Turbo-FLASH. Nevertheless, in two other cases, the Gd-enhanced 3DTFL gave false negative (FN) results while the T1-weighted SE images enabled correct localisation. Replacement of T1-weighted SE by 3DTFL cannot therefore be advocated and use of both contrast-enhanced sequences offers the highest detection capability for microadenomas.
authors.affiliation: Department of Radiology and Medical Imaging, University Hospital V.U.B., Brussels, Belgium.
authors.forename: T
authors.initials: T
authors.lastname: Stadnik
authors.forename: J
authors.initials: J
authors.lastname: D'Haens
authors.forename: R
authors.initials: R
authors.lastname: Luypaert
authors.forename: M
authors.initials: M
authors.lastname: Osteaux
mesh_terms: D000236:Adenoma / Q000175:diagnosis* / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D003287:Contrast Media / Q000008:administration & dosage; D005682:Gadolinium / Q000008:administration & dosage; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D015175:Prolactinoma / Q000175:diagnosis; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D000324:Adrenocorticotropic Hormone; D005682:Gadolinium