Pulmonary endocrine cells in plexogenic pulmonary arteriopathy associated with cirrhosis.
A clear association has been described between numbers of pulmonary endocrine cells and the migration and/or proliferation of myofibroblasts which is thought to underlie the vascular changes seen in plexogenic pulmonary arteriopathy due to cardiac shunts and primary pulmonary hypertension. In contrast, the pulmonary endocrine system in a subject with florid pulmonary plexogenic arteriopathy associated with cirrhosis was entirely normal, suggesting possible differences in its pathogenesis.
Gosney
J R
JR
Department of Pathology, University of Liverpool, UK.
Resl
M
M
D000328:Adult; D004702:Endocrine Glands / Q000473:pathology*; D004700:Endocrine System Diseases / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology / Q000473:pathology; D008103:Liver Cirrhosis / Q000150:complications / Q000473:pathology*; D008171:Lung Diseases / Q000209:etiology / Q000473:pathology*; D011651:Pulmonary Artery / Q000473:pathology*; D014652:Vascular Diseases / Q000209:etiology / Q000473:pathology