[Isochromanylpencillins].
(R/S)-Isochroman-1-carboxylic acid (1) is resolved to its enantiomers and as well as these reacted with 6-aminopenicillanic acid to the title compounds 2. The activity of the new penicillin-derivatives against gram positive and gram negative bacteria is compared with that of benzyl penicillin.
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Institut für Pharmazeutische Chemie, Westfälischen Wilhelms-Universität, Münster.
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D001419:Bacteria / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000138:chemical synthesis* / Q000494:pharmacology
D010406:Penicillins
Isochromanylpenicilline.