title: Prevalence of cytomegalovirus antibody in Thai-northeastern blood donors.
abstract: The prevalence of cytomegalovirus antibody was studied in sera of 359 Northeastern blood donors with an age range of 17-59 years by ELISA for anti-CMV total antibody (anti-CMV). Anti-CMV was detected in 93.31% (335/359) of blood donors. The prevalence in males was 91.53% (227 in 248) while female donors showed 97.30% (108 in 111) positive for anti-CMV. The results demonstrated no statistical difference between sex and age. One-hundred and eighty serum samples with positive anti-CMV were reexamined for anti-CMV IgM antibody. Only one sample was found to be positive. This study suggested that CMV seronegative blood supply was very limited. Therefore leukocyte-depleted blood should be the method of choice for prevention of post-transfusion CMV infections in high risk recipients.
authors.affiliation: Department of Clinical Immunology, Faculty of Associated Medical Sciences, Khon Kaen University, Thailand.
authors.forename: Y
authors.initials: Y
authors.lastname: Urwijitaroon
authors.forename: S
authors.initials: S
authors.lastname: Teawpatanataworn
authors.forename: A
authors.initials: A
authors.lastname: Kitjareontarm
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D001782:Blood Donors / Q000706:statistics & numerical data*; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000453:epidemiology* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D016036:Seroepidemiologic Studies; D013785:Thailand / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M