The GCGGAA gene-regulatory motif of herpes simplex virus type-1 is also found in hepatitis C virus.
We have analyzed the sequence of the 5'-untranslated region of hepatitis C virus from 24 patients with chronic hepatitis C and we found a conserved six-nucleotide motif previously described as a modulator of gene expression.
Vizmanos
J L
JL
Department of Genetics, School of Medicine, University of Navarra, Pamplona, Spain.
Jauregui
J I
JI
Gullón
A
A
González
C J
CJ
Civeira
M P
MP
Prieto
J
J
García-Delgado
M
M
D001483:Base Sequence; D015967:Gene Expression Regulation, Viral; D016174:Hepacivirus / Q000235:genetics* / Q000302:isolation & purification; D006526:Hepatitis C / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000235:genetics; D012045:Regulatory Sequences, Nucleic Acid; D018139:Simplexvirus / Q000235:genetics*
D012367:RNA, Viral