title: Synthesis of pyridylethenyl derivatives of 3H-pyrido[2,3-d]-pyrimidyn-4-on of expected depressive activity on central nervous system. Part I.
abstract: Synthesis of 2-(pyridylethenyl) derivatives of 3H-pyrido[2,3-d]pyrimidin-4-on [Va-k] by condensation of selected 2-methyl-3H-pyrido[2,3-d]pyrimidin-4-ones [IVa-k] with nicotinic aldehyde is described. Compounds [Vh] and [Vi] showed weak analgetic activities.
authors.affiliation: Department of Drug Technology, School of Medicine, Warsaw, Poland.
authors.forename: F
authors.initials: F
authors.lastname: Herold
authors.forename: B
authors.initials: B
authors.lastname: Gutkowska
authors.forename: A
authors.initials: A
authors.lastname: Baranowski
authors.forename: M
authors.initials: M
authors.lastname: Kałucka
authors.forename: E
authors.initials: E
authors.lastname: Helbin
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D051379:Mice; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity
chemical_list: D000700:Analgesics; D011743:Pyrimidines