title: Simian AIDS type D serogroup 2 retrovirus: isolation of an infectious molecular clone and sequence analyses of its envelope glycoprotein gene and 3' long terminal repeat.
abstract: We describe the molecular cloning of a serogroup 2 simian retrovirus (SRV; D2/RHE/OR) and present the sequence of its envelope (env) glycoprotein gene and 3' long terminal repeat region. This report documents the first infectious molecular clone of a serogroup 2 SRV and provides env sequence verification of genetic diversity among serogroup 2 SRV isolates.
authors.affiliation: Division of Primate Medicine, Oregon Regional Primate Research Center, Oregon Health Sciences University, Beaverton 97006.
authors.forename: G H
authors.initials: GH
authors.lastname: Marracci
authors.forename: R D
authors.initials: RD
authors.lastname: Kelley
authors.forename: K Y
authors.initials: KY
authors.lastname: Pilcher
authors.forename: L
authors.initials: L
authors.lastname: Crabtree
authors.forename: S M
authors.initials: SM
authors.lastname: Shiigi
authors.forename: N
authors.initials: N
authors.lastname: Avery
authors.forename: G
authors.initials: G
authors.lastname: Leo
authors.forename: M C
authors.initials: MC
authors.lastname: Webb
authors.forename: L M
authors.initials: LM
authors.lastname: Hallick
authors.forename: M K
authors.initials: MK
authors.lastname: Axthelm
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D003001:Cloning, Molecular; D004279:DNA, Viral; D015686:Gene Products, env / Q000235:genetics*; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D015301:Retroviruses, Simian / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity / Q000502:physiology; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D012703:Serotyping; D016097:Simian Acquired Immunodeficiency Syndrome / Q000821:virology*; D014162:Transfection; D014774:Virulence / Q000235:genetics
chemical_list: D004279:DNA, Viral; D015686:Gene Products, env