title: Antiphospholipid antibody syndrome associated with ovarian cancer. A new paraneoplastic syndrome?
abstract: We describe a 41-year-old woman, in whom antiphospholipid antibody syndrome (APS) occurred at presentation, before the detection of an ovarian endometrial adenocarcinoma. This syndrome was characterized by widespread and worsening thromboembolism and it did not respond to conventional anticoagulant treatment. The paraneoplastic nature of this APS was strongly suggested by the disappearance of both thromboembolism and antiphospholipid antibodies only after surgical removal of the cancer.
authors.affiliation: Division of Rheumatology, University of Padova, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Ruffatti
authors.forename: S
authors.initials: S
authors.lastname: Aversa
authors.forename: T
authors.initials: T
authors.lastname: Del Ross
authors.forename: S
authors.initials: S
authors.lastname: Tonetto
authors.forename: M
authors.initials: M
authors.lastname: Fiorentino
authors.forename: S
authors.initials: S
authors.lastname: Todesco
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000097:blood; D016736:Antiphospholipid Syndrome; D005260:Female; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D010051:Ovarian Neoplasms / Q000601:surgery; D010257:Paraneoplastic Syndromes / Q000601:surgery; D013923:Thromboembolism
chemical_list: D017153:Antibodies, Anticardiolipin; D016682:Lupus Coagulation Inhibitor