title: [Assay of R-plasmid and antibiotic resistance spectrum in 286 strains of gram-negative bacteria].
abstract: This paper reports the results of the sensitivity test to 10 antibiotics and the assay of R-plasmid on 286 strains of Gram-negative bacteria isolated from hospitals. It was found that the main prevalent resistant bacteria are Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae. Their major antibiotic resistance spectrum is: Ampicillin, Carbenicillin, Chloramphemicol, Gentamicin, Furbenicillin. The results showed that 272 of 283 strains resisted to 1-9 antibiotics (95.1%). One-hundred and seventy-eight of 286 strains resisted to more than 4 antibiotics (62.2%). One-hundred and fifty-one of 286 strains carried R-plasmid in resistant bacteria (53.3%). 13.3% resistance markers were transferred with the whole R-factor. But 86.7% resistance markers were transferred with only a part of R-factor.
authors.affiliation: Institute of Clinical Pharmacology, Beijing Medical University.
authors.forename: Q
authors.initials: Q
authors.lastname: Wang
authors.forename: G
authors.initials: G
authors.lastname: Xu
authors.forename: J
authors.initials: J
authors.lastname: Li
mesh_terms: D000668:Ampicillin Resistance / Q000235:genetics*; D002228:Carbenicillin / Q000494:pharmacology; D004352:Drug Resistance, Microbial / Q000235:genetics; D018432:Drug Resistance, Multiple / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D011815:R Factors
chemical_list: D002228:Carbenicillin