title: HTLV type I and HTLV type II infection among Indians and natives from Argentina.
abstract: Endemic foci for HTLV-II infection have been identified in several Amerindian populations. To determine HTLV-I and/or HTLV-II infection among Amerindians living in Argentina we studied 454 sera or plasmas from Indians and natives from different areas of our country. All samples were tested by the particle agglutination technique, and positive reactions were confirmed by the immunofluorescence assay (IFA). IFA titration was used to differentiate HTLV-I and HTLV-II antibodies. Twenty-three of 222 samples (10.4%) were found positive among the Tobas Indians; 22 samples were typed as HTLV-II and 1 as HTLV-I. Antibodies for HTLV-I were found in the serum and CSF of three natives from Salta with a TSP diagnosis. No positive samples were found among 96 Mapuche Indians and 133 natives from San Luis. Our results indicate that HTLV-II is endemic among the Tobas Indians. In this study, infection by these retroviruses in Argentinian Amerindians seems to have a marked geographic distribution.
authors.affiliation: Grupo de Trabajo de SIDA Pediátrico, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina.
authors.forename: M B
authors.initials: MB
authors.lastname: Bouzas
authors.forename: I
authors.initials: I
authors.lastname: Zapiola
authors.forename: S
authors.initials: S
authors.lastname: Quiruelas
authors.forename: D
authors.initials: D
authors.lastname: Gorvein
authors.forename: A
authors.initials: A
authors.lastname: Panzita
authors.forename: J
authors.initials: J
authors.lastname: Rey
authors.forename: F P
authors.initials: FP
authors.lastname: Carnese
authors.forename: R
authors.initials: R
authors.lastname: Corral
authors.forename: C
authors.initials: C
authors.lastname: Perez
authors.forename: C
authors.initials: C
authors.lastname: Zala
mesh_terms: D000293:Adolescent; D000328:Adult; D001118:Argentina / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000097:blood / Q000235:genetics; D005260:Female; D015481:HTLV-I Antibodies / Q000097:blood / Q000134:cerebrospinal fluid; D015490:HTLV-I Infections / Q000453:epidemiology* / Q000276:immunology; D015482:HTLV-II Antibodies / Q000097:blood / Q000134:cerebrospinal fluid; D015491:HTLV-II Infections / Q000453:epidemiology* / Q000276:immunology; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000302:isolation & purification; D015367:Human T-lymphotropic virus 2 / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007199:Indians, South American; D007223:Infant; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral; D015481:HTLV-I Antibodies; D015482:HTLV-II Antibodies