Enhancement of halothane action at the ryanodine receptor by unsaturated fatty acids.
Fletcher
J E
JE
Department of Anesthesiology, Hahnemann University, Philadelphia, Pennsylvania 19102.
Welter
V E
VE
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000187:drug effects*; D002352:Carrier Proteins / Q000378:metabolism; D004357:Drug Synergism; D000071438:Fatty Acid-Binding Protein 7; D050556:Fatty Acid-Binding Proteins; D006221:Halothane / Q000494:pharmacology*; D008297:Male; D009124:Muscle Proteins / Q000187:drug effects*; D009206:Myocardium / Q000378:metabolism; D009363:Neoplasm Proteins; D009419:Nerve Tissue Proteins; D019301:Oleic Acid; D009829:Oleic Acids / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D019837:Ryanodine Receptor Calcium Release Channel; D012519:Sarcoplasmic Reticulum / Q000378:metabolism; D012710:Serum Albumin, Bovine / Q000378:metabolism
D015220:Calcium Channels; D002352:Carrier Proteins; C490174:Fabp7 protein, rat; D000071438:Fatty Acid-Binding Protein 7; D050556:Fatty Acid-Binding Proteins; D009124:Muscle Proteins; D009363:Neoplasm Proteins; D009419:Nerve Tissue Proteins; D009829:Oleic Acids; D019837:Ryanodine Receptor Calcium Release Channel; D012710:Serum Albumin, Bovine; D019301:Oleic Acid; D002118:Calcium; D006221:Halothane