title: Obtention of ovine IgE from heterohybridoma.
abstract: Mesenteric and bronchial lymph node cells from sheep immunized with Ascaris suum antigens in combination with Bordetella pertussis vaccine were fused with mouse myeloma cell lines, P3-X63-Ag8.653, NSO.U and NS1.1.Ag1.1. One heterohybridoma cell line (NS1.1.Ag1.1 x sheep) producing ovine immunoglobulin E was detected by the passive cutaneous anaphylaxis test.
authors.affiliation: University of Bristol, School of Veterinary Science, Department of Veterinary Medicine, Langford, UK.
authors.forename: H
authors.initials: H
authors.lastname: Yilmaz
authors.forename: K
authors.initials: K
authors.lastname: Haverson
authors.forename: K L
authors.initials: KL
authors.lastname: Morgan
mesh_terms: D000818:Animals; D017165:Ascaris suum / Q000276:immunology; D001886:Bordetella pertussis / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006825:Hybridomas / Q000276:immunology*; D007073:Immunoglobulin E / Q000096:biosynthesis*; D051379:Mice; D010047:Ovalbumin / Q000276:immunology; D010323:Passive Cutaneous Anaphylaxis; D012756:Sheep / Q000276:immunology*; D013997:Time Factors
chemical_list: D007073:Immunoglobulin E; D010047:Ovalbumin