title: [Amnestic syndromes and confabulation in infarction of the posterior cerebral artery area].
abstract: The Posterior Cerebral Artery (PCA) supplies the greatest part of the limbic system. Several authors have reported amnestic syndromes in PCA infarcts. Amongst 76 patients with a CT proven PCA infarct, 21 suffered anterograde amnesia. Confabulations were associated in 5 cases. We studied CT scans according to previously reported templates in the 21 amnestic patients: all patients with confabulations had a paramedian or a tuberothalamic infarct associated with a cortical infarct within the superficial territory of the PCA. None of the 16 remainders had a thalamic lesion. These results emphasize the role of the thalamus especially of the dorsomedial nucleus in the pathogenesis of confabulation. The underlying mechanism could imply fronto-cingular deafferentation.
authors.affiliation: Service de Neurologie (Pr P. Brunet), Hôpital de la Salpêtrière, Paris.
authors.forename: J
authors.initials: J
authors.lastname: Servan
authors.forename: P
authors.initials: P
authors.lastname: Verstichel
authors.forename: M
authors.initials: M
authors.lastname: Catala
authors.forename: G
authors.initials: G
authors.lastname: Rancurel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000647:Amnesia / Q000209:etiology*; D002544:Cerebral Infarction / Q000150:complications* / Q000175:diagnosis; D005201:Fantasy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013788:Thalamus; D014057:Tomography, X-Ray Computed
vernacular_title: Syndromes amnésiques et fabulations au cours d'infarctus du territoire de l'artère cérébrale postérieure.