[Antioxidant effect of a phospholipid complex isolated from marine organisms].
Antioxidative effect of phospholipid complex from the sea organisms (preparation "Kalmofil") is observed comparatively with other phospholipid fractions of animal and plant origin. Most antioxidative action of the phospholipid complex from Mollusca (preparation "Kalmofil") on the nonenzymatic LPO reactions in vitro is established. Analogous fractions from different functional animal tissues have not such influence. Application of "Kalmofil" in vivo under experimental rat hepatitis provoked by CCl4 has a corrective effect on both nonenzymatic and Fe(2+)- and NADP.H-depending LPO reactions. This preparation decreases toxic influence of CCl4 and improves antioxidative system of rat hepatocytes.
Shakhman
E V
EV
Datsenko
Z M
ZM
Shumeĭko
V N
VN
D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D002251:Carbon Tetrachloride; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy; D049832:Decapodiformes / Q000737:chemistry*; D066298:In Vitro Techniques; D015227:Lipid Peroxidation; D010743:Phospholipids / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D014810:Vitamin E / Q000494:pharmacology
D000975:Antioxidants; D010743:Phospholipids; C092327:kalmofil; D014810:Vitamin E; D002251:Carbon Tetrachloride
Antioksidantnoe deĭstvie fosfolipidnogo kompleksa, vydelennogo iz morskikh organizmov.