title: Abnormal cervical cytology in adolescents. A 15-year experience.
abstract: The onset of sexual activity at a young age (< 17 years) has been identified in several studies as the most important epidemiologic risk factor in the development of cervical intraepithelial neoplasia (CIN). In characterizing the natural history of CIN, investigators have indicated that a percentage of such lesions progress to invasive carcinoma if left untreated. CIN in adolescents was first reported in 1961. The subsequently reported CIN prevalence rates in sexually active, medically indigent teenage populations have increased over time, temporally paralleling increasing early sexual activity among teenagers. In our 15-year experience with abnormal cervical cytology in adolescents, all grades of CIN were observed. Fully 13% of patients had histologically proven CIN 3, a preinvasive lesion. Given reports of an increase in cervical cancer in young women (< 35 years old), the findings of this and similar studies mandate routine cervical cytologic screening in all sexually active teenage girls.
authors.affiliation: Department of Obstetrics and Gynecology, Cornell University Medical Center, New York, NY 10021.
authors.forename: K
authors.initials: K
authors.lastname: Economos
authors.forename: N
authors.initials: N
authors.lastname: Perez-Veridiano
authors.forename: M
authors.initials: M
authors.lastname: Mann
authors.forename: I
authors.initials: I
authors.lastname: Delke
authors.forename: M L
authors.initials: ML
authors.lastname: Tancer
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000328:Adult; D005260:Female; D006801:Humans; D012725:Sexual Behavior; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000517:prevention & control; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000517:prevention & control