Solubility and micelle-water partitioning of polychlorinated biphenyls in solutions of bile salt micelles.
Experimental data are presented on the enhanced solubilities and micelle/water partition coefficients of 14 polychlorinated biphenyls (PCBs) in solutions of the bile salts sodium taurocholate (TC) and sodium taurodeoxycholate (TDC) below and above the critical micellar concentration (CMC). Solubilities of PCBs in micellar solutions above the CMC depend linearly on bile salt concentration and the solubility enhancement is up to four orders of magnitude. PCB partition coefficients (log Kmw) are independent of bile salt concentrations and are systematically higher in solutions of TDC than in solutions of TC, ranging from 4.26 to 6.24 and from 3.89 to 5.89 respectively. The partitioning behavior of the pertinent extremely hydrophobics between the aqueous and micellar phases is not completely comparable with simple organic solvent/water systems and the correlation between log Kow and log Kmw is non-linear.
Dulfer
W J
WJ
Department of Environmental and Toxicological Chemistry, Amsterdam Research Institute for Substances in Ecosystems, University of Amsterdam, The Netherlands.
Govers
H A
HA
D008823:Micelles; D011078:Polychlorinated Biphenyls / Q000737:chemistry*; D012995:Solubility; D013656:Taurocholic Acid / Q000737:chemistry*; D013657:Taurodeoxycholic Acid / Q000737:chemistry*
D008823:Micelles; D013657:Taurodeoxycholic Acid; D013656:Taurocholic Acid; D011078:Polychlorinated Biphenyls