[Experimental study of the utilization of combined interferon chemotherapy in the treatment of laryngeal cancer].
We have studied the effects of different chemotherapy drugs and/or interferons on the laringeal cancer cell line HLa-79. The best anti-proliferative effect was achieved using interferon-beta. A combination of 5-fluoracil and interferon-beta was the only one that resulted in a synergistic anti-proliferative effect.
Bergler
W
W
Departamento de ORL, Klinikum Mannheim, Universidad de Heidelberg-Mannheim.
Bujía
J
J
D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D002465:Cell Movement / Q000187:drug effects; D004357:Drug Synergism; D004358:Drug Therapy; D004359:Drug Therapy, Combination; D006801:Humans; D016899:Interferon-beta / Q000494:pharmacology* / Q000627:therapeutic use*; D007822:Laryngeal Neoplasms / Q000188:drug therapy*; D007830:Larynx / Q000187:drug effects* / Q000473:pathology
D000970:Antineoplastic Agents; D016899:Interferon-beta
Estudio experimental sobre la utilización de quimioterapia combinada a interferones en el tratamiento del cáncer laríngeo.