[Special qualification of a photometric procedure for determination of salicylic acid in therapeutic drug monitoring].
A procedure for the determination of salicylic acid from human serum is presented. It is based on an acidic extraction, a basic reextraction and the detection of salicylic acid as its iron-III-complex by photometry. The procedure is quantitative over a wide range of linearity, easy to carry out and is especially suitable for therapeutic drug monitoring in the treatment of juvenile rheumatoid arthritis.
Martens
J
J
Institut für Klinische Pharmakologie, Otto-von-Guericke-Universität Magdeburg.
Meyer
F P
FP
D001171:Arthritis, Juvenile / Q000097:blood; D002138:Calibration; D016903:Drug Monitoring / Q000379:methods*; D005296:Ferrous Compounds / Q000737:chemistry; D006801:Humans; D010783:Photometry; D012459:Salicylates / Q000097:blood*; D020156:Salicylic Acid
D005296:Ferrous Compounds; D012459:Salicylates; D020156:Salicylic Acid
Besondere Eignung eines photometrischen Verfahrens zur Bestimmung von Salicylsäure im Therapeutischen Drug Monitoring.