title: Codon usage and genome evolution.
abstract: The rates and patterns of evolution at silent sites in codons reveal much about the basic features of molecular evolution. Recent increases in the amount of sequence data available for various species and more precise knowledge of the chromosomal locations of those sequences, coming in particular from genome projects, reveal that some features of molecular evolution vary around the genome.
authors.affiliation: Department of Genetics, University of Nottingham, Queens Medical Centre, UK.
authors.forename: P M
authors.initials: PM
authors.lastname: Sharp
authors.forename: G
authors.initials: G
authors.lastname: Matassi
mesh_terms: D000818:Animals; D001482:Base Composition; D005075:Biological Evolution; D003062:Codon / Q000235:genetics*; D018509:DNA, Helminth / Q000235:genetics; D015226:Dinucleoside Phosphates / Q000378:metabolism; D004330:Drosophila / Q000235:genetics; D005786:Gene Expression Regulation; D017344:Genes, Insect / Q000235:genetics; D016678:Genome; D016680:Genome, Bacterial; D016681:Genome, Fungal; D015894:Genome, Human; D006801:Humans; D008322:Mammals / Q000235:genetics; D014176:Protein Biosynthesis; D012641:Selection, Genetic; D013045:Species Specificity
chemical_list: D003062:Codon; D018509:DNA, Helminth; D015226:Dinucleoside Phosphates; C015772:CpG dinucleotide