title: Cell wall anchoring to cytoplasmic membrane of Candida albicans.
abstract: Cell wall ultrastructure of the opportunistic pathogenic yeast Candida albicans was investigated by stereoscopic freeze-etching technique. Three wall layers were distinguishable by this technique. No clear periplasmic space was evident. Bilayer membrane invaginations were extensive. The outermost regions of the membrane invaginations were lined with thin, spine-like fibrils, which extended into the cell wall. We suggest that the fibrils along the invaginations are involved in anchoring the cell wall to the membrane.
authors.affiliation: Department of Pathology, University of Virginia Health Sciences Center, Charlottesville 22908.
authors.forename: K C
authors.initials: KC
authors.lastname: Hazen
authors.forename: B W
authors.initials: BW
authors.lastname: Hazen
authors.forename: M M
authors.initials: MM
authors.lastname: Allietta
mesh_terms: D002176:Candida albicans / Q000302:isolation & purification / Q000472:pathogenicity / Q000648:ultrastructure*; D002462:Cell Membrane / Q000648:ultrastructure*; D002473:Cell Wall / Q000648:ultrastructure*; D005613:Freeze Etching / Q000379:methods; D005614:Freeze Fracturing / Q000379:methods; D006801:Humans; D008854:Microscopy, Electron / Q000379:methods