Stuttering induced by theophylline.
We retrospectively evaluated three fluent asthmatic children who developed speech dysfluency following administration of theophylline. The dysfluency ceased in all three, following discontinuation of the medication. The medication was re-instituted in two patients, prompting return of dysfluency. It is unknown whether the patients had characteristics of "acquired stuttering" or "developmental stuttering." We urge appropriate testing should this complication again occur. This might then provide pharmacologic information regarding stuttering.
Rosenfield
D B
DB
Department of Neurology, Baylor College of Medicine, Houston, Texas 77030.
McCarthy
M
M
McKinney
K
K
Viswanath
N S
NS
Nudelman
H B
HB
D001249:Asthma / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013342:Stuttering / Q000139:chemically induced*; D013806:Theophylline / Q000009:adverse effects*
D013806:Theophylline