Decamer peptide derived from the alpha 1 helix of the first domain of HLA-B7 01 prolongs allograft survival in rats with an inhibition of graft infiltrating cell cytotoxicity.
Cuturi
M C
MC
INSERM U211 Plateau Technique, Nantes, France.
Josien
R
R
Cantarovich
D
D
Douillard
P
P
Pannetier
C
C
Smit
H
H
Ménoret
S
S
Pouletty
P
P
Clayberger
C
C
Soulillou
J P
JP
D000818:Animals; D003602:Cytotoxicity, Immunologic; D015870:Gene Expression / Q000276:immunology; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D015793:HLA-B7 Antigen / Q000737:chemistry / Q000627:therapeutic use*; D016027:Heart Transplantation / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis; D016753:Interleukin-10 / Q000096:biosynthesis; D007376:Interleukin-2 / Q000096:biosynthesis; D008213:Lymphocyte Activation; D008297:Male; D010446:Peptide Fragments / Q000737:chemistry / Q000627:therapeutic use*; D016133:Polymerase Chain Reaction; D017433:Protein Structure, Secondary; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis; D051381:Rats; D011917:Rats, Inbred Lew; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D014184:Transplantation, Homologous
D015793:HLA-B7 Antigen; D007376:Interleukin-2; D010446:Peptide Fragments; D012333:RNA, Messenger; D016753:Interleukin-10; D007371:Interferon-gamma