title: [Bronchiolo-alveolar carcinoma: review of 14 cases].
abstract: Fourteen cases are revised of bronchiolalveolar carcinoma (BAC) diagnosed in our institution from 1980 to 1992. The time interval from clinical manifestations to diagnosis was 5.13 +/- 6.01 months. The incidence of smokers in the population was 42.8%. Clinical findings were non-specific, except in three cases, consisting in bronchorrhea with more than 100 ml. The most frequent site of the tumor was bilateral and diffuse (71%), mainly in nonsmokers. Endoscopic findings suggested a likely malignancy in 21% of cases. Transbronchial biopsy was the most sensitive diagnostic method. Histological confirmation was obtained in 85% of cases. To note the possible association with Epstein-Barr virus (EBV), as demonstrated by the findings of EBV genome in the cases when this study was performed.
authors.affiliation: Servicio de Neumología, Hospital Ramón y Cajal, Madrid.
authors.forename: L
authors.initials: L
authors.lastname: Máiz
authors.forename: J
authors.initials: J
authors.lastname: Flandes
authors.forename: A
authors.initials: A
authors.lastname: Perpiñá
authors.forename: L
authors.initials: L
authors.lastname: Fogué
authors.forename: E
authors.initials: E
authors.lastname: Pérez-Rodríguez
mesh_terms: D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000175:diagnosis / Q000209:etiology; D000328:Adult; D000368:Aged; D001999:Bronchoscopy; D005260:Female; D006566:Herpesviridae Infections / Q000150:complications; D004854:Herpesvirus 4, Human; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects; D014412:Tumor Virus Infections / Q000150:complications
vernacular_title: Carcinoma bronquioloalveolar: revisión de catorce casos.