MR signal characteristics of cadaveric bone allografts in three children with primary bone tumors treated with limb salvage therapy.
Three children with adult cadaveric bone allografts for the treatment of bone malignancies are presented. Follow-up magnetic resonance (MR) imaging demonstrated decreased signal on T1-weighted imaging and increased signal on T2-weighted imaging in the allograft without clinical evidence of recurrent disease. These signal characteristics appear to be a normal finding in cadaveric bone allografts and should not be mistaken for recurrence. The finding may reflect persistent marrow necrosis within the allograft marrow cavity.
Levin
T L
TL
Babies Hospital, Department of Radiology, Columbia-Presbyterian Medical Center, New York, NY 10032.
Miller
T T
TT
Panicek
D M
DM
Rosenfield
N
N
Ruzal-Shapiro
C
C
Dick
H S
HS
Berdon
W E
WE
D000293:Adolescent; D001859:Bone Neoplasms / Q000175:diagnosis / Q000601:surgery*; D016025:Bone Transplantation / Q000473:pathology*; D002102:Cadaver; D002648:Child; D005260:Female; D005266:Femoral Neoplasms / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis / Q000601:surgery*; D016879:Salvage Therapy; D012512:Sarcoma, Ewing / Q000175:diagnosis / Q000601:surgery*; D013977:Tibia