Effects of electro-acupuncture and physical exercise on regional concentrations of neuropeptides in rat brain.
The effects of single or repeated treatments with manual acupuncture (ACU), electro-acupuncture (ELACU) or physical exercise on neuropeptide Y (NPY), neurokinin A (NKA), substance P (SP), galanin (GAL) and vasoactive intestinal peptide (VIP)-like immunoreactivity (-LI) in different regions of the rat brain were studied. Initially the effect of microwave irradiation (MWI) was compared to decapitation on the recovery of neuropeptides, and significantly higher concentrations of SP-LI, NKA-LI and NPY-LI were found in the hippocampus, occipital cortex, pituitary and striatum following MWI. Repeated ELACU treatments significantly increased SP-LI, NKA-LI and NPY-LI in the hippocampus and NPY-LI in the occipital cortex. No changes were found in animals receiving ACU or performing physical exercise.
Bucinskaite
V
V
Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Lundeberg
T
T
Stenfors
C
C
Ekblom
A
A
Dahlin
L
L
Theodorsson
E
E
D015670:Acupuncture Therapy; D000818:Animals; D001923:Brain Chemistry / Q000502:physiology* / Q000528:radiation effects; D015671:Electroacupuncture; D006624:Hippocampus / Q000378:metabolism / Q000502:physiology / Q000528:radiation effects; D008297:Male; D008872:Microwaves; D017072:Neostriatum / Q000378:metabolism / Q000502:physiology / Q000528:radiation effects; D009479:Neuropeptides / Q000378:metabolism*; D009778:Occipital Lobe / Q000378:metabolism / Q000502:physiology / Q000528:radiation effects; D005082:Physical Exertion / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D009479:Neuropeptides