A combination of sulphadiazine, trimethoprim and metronidazole or tinidazole in kala-azar.
Nine patients of kala-azar showed good response to treatment with a combination of sulphadiazine, trimethoprim and metronidazole or tinidazole given orally for 12 to 25 weeks. No untoward side effect was noticed. Tinidazole sulphadiazine and trimethoprim combination was found to be safer for treatment of kala-azar in pregnant women.
Bano
P
P
Sadar Hospital Biharsharif, Nalanda, Bihar.
Shahab
S M
SM
D000328:Adult; D000818:Animals; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007893:Leishmania donovani; D007898:Leishmaniasis, Visceral / Q000188:drug therapy*; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage*; D012008:Recurrence; D013411:Sulfadiazine / Q000008:administration & dosage*; D014011:Tinidazole / Q000008:administration & dosage*; D014295:Trimethoprim / Q000008:administration & dosage*
D014011:Tinidazole; D013411:Sulfadiazine; D008795:Metronidazole; D014295:Trimethoprim