Connective tissue metabolism including cytokines in scleroderma.
The currently published literature on systemic sclerosis underscores the importance of vascular-leukocyte adhesion and perturbations of cytokines and growth factors that reflect T-cell activation and abnormal stimulation of fibroblast growth and matrix synthesis. Articles dealing with these topics are reviewed.
Postlethwaite
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AE
Department of Medicine, University of Tennessee, Memphis 38163.
D002448:Cell Adhesion; D003238:Connective Tissue / Q000378:metabolism* / Q000473:pathology; D016207:Cytokines / Q000378:metabolism*; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D009132:Muscles / Q000378:metabolism / Q000473:pathology; D012595:Scleroderma, Systemic / Q000378:metabolism* / Q000473:pathology
D016207:Cytokines