Eosinophilia-myalgia syndrome, toxic-oil syndrome, and diffuse fasciitis with eosinophilia.
Eosinophilia-myalgia syndrome, a recently described illness, reached epidemic proportions in 1989 and was linked to the ingestion of L-tryptophan containing trace amounts of several contaminants. Eosinophilia-myalgia syndrome shares many clinical and pathologic similarities with toxic-oil syndrome, an epidemic linked to the ingestion of adulterated cooking oil that occurred in Spain in 1981, and to diffuse fasciitis with eosinophilia, a condition first described in 1974. Over the past year, much work has been done in understanding the etiology and pathogenesis of eosinophilia-myalgia syndrome and toxic-oil syndrome. Follow-up data detailing the long-term sequelae and mortality rates for these two conditions are becoming available. The results from these studies are reviewed in this paper.
Bolster
M B
MB
Medical University of South Carolina, Division of Rheumatology and Immunology, Charleston 29425-2229.
Silver
R M
RM
D001937:Brassica; D004802:Eosinophilia / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D016603:Eosinophilia-Myalgia Syndrome / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005208:Fasciitis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005229:Fatty Acids, Monounsaturated; D005260:Female; D006801:Humans; D008297:Male; D010938:Plant Oils / Q000506:poisoning*; D000074262:Rapeseed Oil; D012307:Risk Factors; D013577:Syndrome
D005229:Fatty Acids, Monounsaturated; D010938:Plant Oils; D000074262:Rapeseed Oil