Treatment of idiopathic renal magnesium wasting with amiloride.
We report a case of an 18-year-old female who presented with severe hypomagnesmia due to idiopathic renal magnesium wasting. Only a partial response was noted with magnesium oxide replacement. Treatment with the potassium-sparing diuretic amiloride led to a further rise in the serum magnesium level, a decrease in the fractional excretion of magnesium and improvement in her symptoms. This case demonstrates an effective treatment for idiopathic renal magnesium wasting.
Bundy
J T
JT
Division of Nephrology, Naval Medical Center, Portsmouth, VA 23708.
Connito
D
D
Mahoney
M D
MD
Pontier
P J
PJ
D000293:Adolescent; D000584:Amiloride / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism; D008274:Magnesium / Q000097:blood* / Q000378:metabolism; D015499:Renal Tubular Transport, Inborn Errors / Q000150:complications / Q000188:drug therapy*; D014883:Water-Electrolyte Imbalance / Q000188:drug therapy* / Q000209:etiology
D000584:Amiloride; D008274:Magnesium