title: Validation of the 16-item Negative Symptom Assessment.
abstract: The dimensional structure of the 16-item Negative Symptom Assessment (NSA-16) was validated in a sample of 223 unmedicated schizophrenic inpatients and cross-validated on an independent sample of 276 patients with schizophrenia. Using a confirmatory factor analytic procedure, a five factor model was found to best characterize the structure of this rating instrument. These factors include: Communication, Emotion/Affect, Social Involvement, Motivation, and Retardation. The latent structure of the NSA-16 is similar to the larger instrument from which it was derived. The findings provide support for a multidimensional model of negative symptoms in schizophrenia and offer a useful measure for their assessment.
authors.affiliation: Psychology Service (116B), Department of Veterans Affairs Medical Center, Allen Park, MI 48101.
authors.forename: B N
authors.initials: BN
authors.lastname: Axelrod
authors.forename: R S
authors.initials: RS
authors.lastname: Goldman
authors.forename: L D
authors.initials: LD
authors.lastname: Alphs
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy; D012565:Schizophrenic Psychology; D016037:Single-Blind Method
chemical_list: D014150:Antipsychotic Agents