title: Isolation of genes from cloned DNA.
abstract: During the past year, improvements in the physical and genetic maps of the human genome, in combination with more efficient methods to isolate genes from cloned DNA, have made an increasing impact on the identification of disease genes. Sequence analysis of genomic DNA and the random sequencing and mapping of cDNA clones is helping to integrate the transcript map with the developing physical and genetic maps.
authors.affiliation: Imperial Cancer Research Fund Laboratories, John Radcliffe Hospital, Headington, Oxford, UK.
authors.forename: A P
authors.initials: AP
authors.lastname: Monaco
mesh_terms: D002874:Chromosome Mapping; D003001:Cloning, Molecular / Q000379:methods*; D004247:DNA / Q000235:genetics*; D018076:DNA, Complementary / Q000235:genetics; D005091:Exons; D005784:Gene Amplification; D015870:Gene Expression; D030342:Genetic Diseases, Inborn / Q000235:genetics; D015894:Genome, Human; D006801:Humans; D017422:Sequence Analysis, DNA
chemical_list: D018076:DNA, Complementary; D004247:DNA