Evaluation of new Granada medium (modified) for the antenatal screening of group B streptococcus.
New Granada medium (NGM), modified by the substitution of trimethoprim for methotrexate, was compared to a selective Todd-Hewitt broth (NPC broth) and direct plating onto Edwards medium for assessment of genital carriage of group B streptococcus in pregnant women. Whilst NGM was found to be less sensitive (85%) than NPC broth (95%) and more sensitive than Edwards medium (67%), its use reduced the direct laboratory cost of screening by approximately 41% and also improved the time to report a result by 24 hrs.
Kelly
V N
VN
Department of Microbiology, Royal Women's Hospital, Carlton, Victoria.
Garland
S M
SM
D001431:Bacteriological Techniques / Q000191:economics; D003365:Costs and Cost Analysis; D003470:Culture Media; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis*; D013292:Streptococcus agalactiae / Q000302:isolation & purification*
D003470:Culture Media