title: Optimization of distal artery opacification in peripheral arteriography: comparison between nitroglycerin, tolazoline and buflomedyl.
abstract: A prospective double blind randomized comparative study was performed in patients with insufficient distal artery opacification during peripheral arteriography, in order to compare the vasodilating capabilities of intraarterially injected nitroglycerin, tolazoline and buflomedyl versus placebo. All three vasodilating agents showed statistically significant improvement of distal artery opacification as compared to the placebo (p < 0.0001). Overall results were better for buflomedyl (p = 0.231) then for tolazoline (p = 0.142) and nitroglycerin, but these differences were statistically not significant. It is concluded that buflomedyl is an excellent vasodilating agent in peripheral arteriography.
authors.affiliation: Department of Radiology, University Hospitals KU Leuven, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Wilms
authors.forename: L
authors.initials: L
authors.lastname: Stockx
authors.forename: A L
authors.initials: AL
authors.lastname: Baert
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D015901:Angiography, Digital Subtraction / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000494:pharmacology; D011446:Prospective Studies; D011759:Pyrrolidines / Q000494:pharmacology; D014043:Tolazoline / Q000494:pharmacology; D014665:Vasodilator Agents / Q000494:pharmacology*
chemical_list: D000317:Adrenergic alpha-Antagonists; D011759:Pyrrolidines; D014665:Vasodilator Agents; D014043:Tolazoline; D005996:Nitroglycerin; C010651:buflomedil