A non-linear fitting program in pharmacokinetics with Microsoft Excel spreadsheet.
We propose a new approach of pharmacokinetics patterns of drugs by use of spreadsheets. We have developed a software program using Microsoft Excel (version 3.0) to determine initial poly exponential parameter values for 1-3 compartment open models and to make non-linear regression with many optimisation procedures. Results are compared with 2 other programs: Nonlin and Rugfit.
Delboy
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AH-AU, Hôpital Sainte-Marguerite, Service de Médecine Interne, Marseille, France.
D000284:Administration, Oral; D000465:Algorithms; D003196:Computer Graphics; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D016014:Linear Models; D008956:Models, Chemical; D004364:Pharmaceutical Preparations / Q000008:administration & dosage; D010599:Pharmacokinetics; D012984:Software; D014018:Tissue Distribution
D004364:Pharmaceutical Preparations