Expressed sequence tags identify a human isolog of the suil translation initiation factor.
The complete cDNA sequence of a human isolog of the yeast suil translation initiation factor gene was obtained by assembling over 40 expressed sequence tags (ESTs) for this gene obtained from a variety of tissue-specific cDNA libraries. The human suilisol gene product is a 113 amino-acid polypeptide similar to proteins known from yeast, rice, mosquito, and Methanococcus. The identification of suilisol illustrates the utility of assemblies of independent ESTs for deriving full-length cDNA sequences for new human genes.
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Institute for Genomic Research, Gaithersburg, MD 20878.
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D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D009033:Culicidae / Q000235:genetics; D018076:DNA, Complementary / Q000032:analysis / Q000737:chemistry / Q000235:genetics*; D015977:Eukaryotic Initiation Factor-1; D005656:Fungal Proteins / Q000235:genetics*; D015870:Gene Expression; D015723:Gene Library; D005800:Genes, Fungal; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D017017:Methanococcus / Q000235:genetics; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D012275:Oryza / Q000235:genetics; D010448:Peptide Initiation Factors / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins; D017386:Sequence Homology, Amino Acid
D018076:DNA, Complementary; D015977:Eukaryotic Initiation Factor-1; D005656:Fungal Proteins; D010448:Peptide Initiation Factors; C072076:SUI1 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins