title: Latency increase of auditory-evoked potential component N1 predicts poor neuroleptic response in schizophrenic patients.
abstract: In a group of 33 acutely ill, previously unmedicated schizophrenic inpatients, the auditory-evoked potential components N1 and P2 were assessed and related to neuroleptic response measured as improvement of the BPRS score during a two-week neuroleptic treatment. N1 latency increase was found to be predictive for a poor neuroleptic response.
authors.affiliation: Central Institute for Mental Health, Unit Neurobiology of Functional Psychoses, Mannheim, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Adler
authors.forename: U
authors.initials: U
authors.lastname: Markert
authors.forename: W F
authors.initials: WF
authors.lastname: Gattaz
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents