title: The importance of the relationship between microalbuminuria, subclinical proteinuria and arterial hypertension in diabetics.
abstract: Arterial hypertension represents, among others, an important risk factor for the development of microalbuminuria in diabetics. On the other hand, with microalbuminuria, it has been observed an important rise in the prevalence of high blood pressure. This study stresses the importance of the relationship between subclinical proteinuria and microalbuminuria, on one hand, and arterial hypertension on the other hand. There have been studied 343 diabetics hospitalized in our Clinic. We estimated the presence of hypertension (according to WHO criteria) and the values of subclinical proteinuria (biuret method) and microalbuminuria (MICRAL-test). We observed that 70.8% of hypertensives and 49.4% of normotensives presented values of proteinuria that ranked between 300 and 500 mg/24 h (p < 0.001). Meanwhile, 25.8% of proteinuric patients and 14.8% of non-proteinuric ones were hypertensives (p < 0.05). In hypertensive diabetics the prevalence of subclinical proteinuria is higher than in normotensive ones. The prevalence of hypertension is significantly higher in microalbuminuric patients than in normoalbuminuric ones.
authors.affiliation: Third Medical Clinic, Department of Diabetes, Nutrition and Metabolic Diseases, Timişoara.
authors.forename: V
authors.initials: V
authors.lastname: Serban
authors.forename: D
authors.initials: D
authors.lastname: Dabelea
mesh_terms: D000419:Albuminuria / Q000453:epidemiology / Q000652:urine*; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology / Q000652:urine*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000652:urine*; D003928:Diabetic Nephropathies / Q000453:epidemiology / Q000652:urine; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000652:urine*; D008297:Male; D015995:Prevalence; D011507:Proteinuria / Q000453:epidemiology / Q000652:urine*; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology