title: A chicken genomic DNA fragment that hybridizes to the murine Hox-3.1 homeobox is likely to encode the NADH ubiquinone oxidoreductase subunit B15.
abstract: A chicken DNA fragment, which was isolated from a cosmid genomic library using a murine homeobox probe, is shown here to be a likely candidate for encoding a protein homologous to the bovine B15 subunit of NADH ubiquinone oxidoreductase. The genomic sequence suggests the presence of an intron separating two coding regions. An alignment between the bovine NADH B15 protein and its putative avian homolog implies the presence of conserved domains, including a transmembrane helix, tyrosine sulfatation site, and a phosphorylation consensus site.
authors.affiliation: University of Hawaii at Manoa, Cancer Research Center, Honolulu 96813.
authors.forename: G S
authors.initials: GS
authors.lastname: Goldberg
authors.forename: W
authors.initials: W
authors.lastname: Kaczmarczyk
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002645:Chickens; D004247:DNA; D004268:DNA-Binding Proteins / Q000235:genetics*; D005801:Genes, Homeobox; D018398:Homeodomain Proteins; D051379:Mice; D008969:Molecular Sequence Data; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; C489816:Hoxc8 protein, mouse; D004247:DNA; D016660:NAD(P)H Dehydrogenase (Quinone)