Neuroleptic malignant syndrome and catatonia. A report of three cases.
In a series of 1007 consecutively admitted patients, 3 cases of neuroleptic malignant syndrome (NMS) were identified (0.3%). All three patients were affected by mood disorders with congruent psychotic features, had shown catatonia just before the onset of NMS, and had been treated with low neuroleptic doses. All of them presented low serum iron levels. The relationship between NMS and catatonia and possible therapeutic decisions are discussed.
Raja
M
M
Ospedale Santo Spirito, Dipartimento di salute mentale USL RM11, Rome, Italy.
Altavista
M C
MC
Cavallari
S
S
Lubich
L
L
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D002389:Catatonia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D003987:Dibenzothiazepines / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis* / Q000628:therapy; D009460:Neurologic Examination / Q000187:drug effects; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology; D012189:Retrospective Studies
D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D006220:Haloperidol