title: Electrophysiological and morphological properties of granule cells: patch-clamp recordings of newborn rabbit olfactory bulb slices.
abstract: Granule cells were investigated by performing whole-cell patch-clamp recordings from thin slices of the olfactory bulb of newborn rabbits. Granule cells were intracellularly stained with Lucifer Yellow in their intact environment. During current-clamp measurements these neurones were characterized by their lack of action potentials upon depolarization. Evidence for a Ca2+ dependent K+ conductance was found. Two types of outward currents were identified in the whole cell mode during voltage clamp; a non-inactivating K+ current that shared some properties of the delayed rectifier K+ current and a non-inactivating K+ current were recorded. No fast inward current was registrated.
authors.affiliation: Neurologische Klinik, Technischen Universität München, FRG.
authors.forename: J
authors.initials: J
authors.lastname: Bufler
authors.forename: T
authors.initials: T
authors.lastname: Opitz
authors.forename: H
authors.initials: H
authors.lastname: Hatt
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D003594:Cytoplasmic Granules / Q000502:physiology; D004594:Electrophysiology; D005971:Glutamates / Q000502:physiology; D018698:Glutamic Acid; D006651:Histocytochemistry; D066298:In Vitro Techniques; D007395:Interneurons / Q000502:physiology; D007546:Isoquinolines; D009830:Olfactory Bulb / Q000502:physiology* / Q000648:ultrastructure; D015221:Potassium Channels / Q000502:physiology; D011817:Rabbits; D013569:Synapses / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000502:physiology
chemical_list: D005971:Glutamates; D007546:Isoquinolines; D015221:Potassium Channels; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; C017475:lucifer yellow