An immunological study on workers occupationally exposed to cadmium.
1. To assess the quantitative relation between exposure to airborne cadmium and various markers of immune function, 37 male workers were examined and compared with unexposed controls. 2. Blood cadmium concentrations were significantly higher in the exposed workers than in the unexposed, as was urine cadmium. 3. No differences in the serum immunoglobulin (IgG, IgM and IgA) levels between two populations were observed. There was also no significant correlation between blood cadmium concentrations and serum immunoglobulin levels of both exposed and control groups, It has been found also that while monocyte counts significantly increased, lymphocyte, neutrophil and eosinophil counts remained unchanged.
Karakaya
A
A
Department of Toxicology, Faculty of Pharmacy, Ankara University, Turkey.
Yücesoy
B
B
Sardas
O S
OS
D000328:Adult; D002104:Cadmium / Q000009:adverse effects* / Q000097:blood / Q000652:urine; D004804:Eosinophils / Q000187:drug effects; D006801:Humans; D007107:Immune System / Q000187:drug effects; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007136:Immunoglobulins / Q000097:blood*; D007958:Leukocyte Count / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009000:Monocytes; D009504:Neutrophils; D016273:Occupational Exposure; D013601:T-Lymphocytes / Q000187:drug effects
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D002104:Cadmium