title: Localization of the gene encoding human phosphatidylinositol transfer protein (PITPN) to 17p13.3: a gene showing homology to the Drosophila retinal degeneration B gene (rdgB).
abstract: The human gene for phosphatidylinositol transfer protein (PITPN) has previously been shown to share sequence and functional homology to part of the Drosophila retinal degeneration B gene (rdgB). In view of the possible involvement of the PITPN locus in the etiology of retinal disease, the gene has been mapped to human chromosome 17p13.3 and mouse Chromosome 11.
authors.affiliation: Department of Molecular Genetics, University of London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Fitzgibbon
authors.forename: A
authors.initials: A
authors.lastname: Pilz
authors.forename: S
authors.initials: S
authors.lastname: Gayther
authors.forename: B
authors.initials: B
authors.lastname: Appukuttan
authors.forename: K S
authors.initials: KS
authors.lastname: Dulai
authors.forename: J D
authors.initials: JD
authors.lastname: Delhanty
authors.forename: G M
authors.initials: GM
authors.lastname: Helmkamp
authors.forename: L R
authors.initials: LR
authors.lastname: Yarbrough
authors.forename: D M
authors.initials: DM
authors.lastname: Hunt
mesh_terms: D000818:Animals; D001483:Base Sequence; D002352:Carrier Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D004330:Drosophila / Q000235:genetics*; D006801:Humans; D008565:Membrane Proteins; D051379:Mice; D008969:Molecular Sequence Data; D049294:Phospholipid Transfer Proteins; D012150:Polymorphism, Restriction Fragment Length; D012162:Retinal Degeneration / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
chemical_list: D002352:Carrier Proteins; D008565:Membrane Proteins; D049294:Phospholipid Transfer Proteins