Activation and function of gamma delta T cells.
T-cell receptor gene rearrangements in gamma delta T cells have been the subject of intense molecular investigations. This year, much has been learned about the mechanisms controlling this process. However, the specificity and function of gamma delta T cells still remains enigmatic. The application of molecular technology including the availability of mutant mice lacking defined T-cell populations and immunologically relevant surface proteins is beginning to provide answers as well as some surprises.
Havran
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WL
Department of Immunology, Scripps Research Institute, La Jolla, California 92037.
Boismenu
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R
D000818:Animals; D006801:Humans; D008213:Lymphocyte Activation; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D016692:Receptors, Antigen, T-Cell, gamma-delta