title: Proctolin promotes vitellogenesis onset in the imaginal molt decapitated cockroach Blaberus craniifer.
abstract: The ovarian response of the imaginal molt decapitated cockroach, Blaberus craniifer, to nanomolar quantities of synthetic proctolin was evaluated. Sites binding anti-egg proteins were detected in the basal oocyte in 67% (18 out of 27) of the treated females, indicating that vitellogenin uptake is mediated by proctolin. The injected concentration of proctolin was consistent with a physiological role. The results suggest that proctolin, a putative neurotransmitter or neuromodulator, possibly acts on a non-excitable cell, the oocyte. At this level, the precise mechanism is discussed with respect to the calcium-dependent processes involved in both the proctolin myogenic effect and vitellogenin uptake in other species of cockroach.
authors.affiliation: Laboratoire de Biologie et Contrôle des Organismes parasites, Faculté de Pharmacie, Université de Paris-Sud, Châtenay-Malabry, France.
authors.forename: F
authors.initials: F
authors.lastname: Goudey-Perrière
authors.forename: C
authors.initials: C
authors.lastname: Perrière
authors.forename: P
authors.initials: P
authors.lastname: Brousse-Gaury
mesh_terms: D000818:Animals; D003058:Cockroaches / Q000502:physiology*; D005260:Female; D007150:Immunohistochemistry; D009479:Neuropeptides; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D009842:Oligopeptides / Q000494:pharmacology*; D009865:Oocytes / Q000187:drug effects / Q000502:physiology; D010053:Ovary / Q000187:drug effects / Q000502:physiology; D014818:Vitellogenesis / Q000187:drug effects*
chemical_list: D009479:Neuropeptides; D018377:Neurotransmitter Agents; D009842:Oligopeptides; C011536:proctolin