Carboprost trometamol in the management of the third stage of labor.
OBJECTIVE
To compare carboprost trometamol with methylergometrine in managing the third stage of labor.


METHODS
One hundred and fifty parturient women were randomly assigned to use carboprost trometamol or methylergometrine immediately after delivery.


RESULTS
Both the duration of the third stage and the mean blood loss were significantly less in the carboprost group than the methergine group (P < 0.001).


CONCLUSIONS
Carboprost trometamol is a more potent uterotonic drug than methylergometrine. Reducing blood loss in parturient women is very important especially in cases where there is the likelihood of anemia.
Abdel-Aleem
H
H
Department of Obstetrics and Gynaecology, Faculty of Medicine, Assiut University, Egypt.
Abol-Oyoun
E M
EM
Moustafa
S A
SA
Kamel
H S
HS
Abdel-Wahab
H A
HA
D000328:Adult; D002260:Carboprost / Q000008:administration & dosage* / Q000009:adverse effects; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007749:Labor Stage, Third / Q000187:drug effects*; D008755:Methylergonovine / Q000008:administration & dosage / Q000009:adverse effects; D006473:Postpartum Hemorrhage / Q000517:prevention & control; D011247:Pregnancy; D014325:Tromethamine / Q000008:administration & dosage* / Q000009:adverse effects; D014590:Uterine Contraction / Q000187:drug effects
D004338:Drug Combinations; D014325:Tromethamine; D002260:Carboprost; C062843:carboprost tromethamine; D008755:Methylergonovine