title: [Preventive total thyroidectomy in children with MEN IIa syndrome].
abstract: Three children of MEN IIa-families underwent a prophylactic total thyroidectomy (at the age of 4, 7 and 8 years). Pathologic examination showed a bilateral C-cell-hyperplasia in each case. The annual follow-up of the physically and mentally well-developing children so far showed normal calcitonin provocative testing. Members of risk families should undergo a screening program as early as possible.
authors.affiliation: Chirurgische Abteilung, Krankenhaus Martha-Maria, München.
authors.forename: T
authors.initials: T
authors.lastname: Schmid
authors.forename: H P
authors.initials: HP
authors.lastname: Mühlig
authors.forename: F
authors.initials: F
authors.lastname: Spelsberg
mesh_terms: D018276:Carcinoma, Medullary / Q000235:genetics* / Q000473:pathology / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D006801:Humans; D006965:Hyperplasia; D008297:Male; D009377:Multiple Endocrine Neoplasia / Q000235:genetics* / Q000473:pathology / Q000517:prevention & control; D011230:Precancerous Conditions / Q000235:genetics / Q000473:pathology / Q000517:prevention & control; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000235:genetics* / Q000473:pathology / Q000517:prevention & control; D013965:Thyroidectomy
vernacular_title: Prophylaktische totale Thyreoidektomie bei Kindern mit MEN IIa-Syndrom.