A study and model of the role of the Renshaw cell in regulating the transient firing rate of the motoneuron.
This study sought to investigate the role of the Renshaw cell with respect to transient motoneuron firing. By studying the cat motoneuron and Renshaw cell, several low-order lumped parameter models were developed that simulate the known characteristics of the injected input current vs. firing rate. The neuron models in the Renshaw cell inhibition configuration were tuned to fit experimental data from cat motoneurons. Models included both linear versions and those with sigmoidal nonlinearities. Results of the simulation indicate that the motoneuron itself provides the adaptation seen in its firing rate and that the Renshaw cell's role is primarily to fine-tune the motoneuron's adaptation process.
Shoemaker
M
M
Department of Electrical Engineering, Seattle Pacific University, WA 98119.
Hannaford
B
B
D000200:Action Potentials; D000465:Algorithms; D000818:Animals; D002415:Cats; D003198:Computer Simulation; D007395:Interneurons / Q000502:physiology*; D008959:Models, Neurological; D009046:Motor Neurons / Q000502:physiology*; D017711:Nonlinear Dynamics; D012371:Robotics; D013116:Spinal Cord / Q000166:cytology* / Q000502:physiology