[Products with high glycemic indices as factors in the metabolic stress of patients with insulin-dependent diabetes mellitus].
Fifty-five patients aged 15-35 years with insulin-dependent diabetes mellitus lasting 3.8 +/- 1.2 years underwent carbohydrate food loading. Within 2 hours after the meal, at 15-min intervals measurements were made of glycemia, C-peptide, insulin, glucagon, hydrocortisone, blood STH levels. Contrary to foodstuffs with low glycemia indices (GI), i.e. vermicelli, buckwheat, the intake of fast absorbed products with high GI (potatoes, hardtack, bread) stimulates glycemia and residual secretion of the islet cells. Enhanced entrance of gastrointestinal glucose into the systemic blood flow and growing insulinemia aroused glucagon secretion depression. The body responses to the above processes, assessed as metabolic stress, with increasing blood hydrocortisone and STH concentrations.
Dreval'
A V
AV
Batashov
M G
MG
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis*; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy; D003927:Diet, Diabetic; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007328:Insulin / Q000008:administration & dosage; D012044:Regression Analysis; D013312:Stress, Physiological / Q000097:blood* / Q000188:drug therapy; D013997:Time Factors
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin
Produkty s vysokimi glikemicheskimi indeksami kak faktory metabolicheskogo stressa u bol'nykh insulinzavisimym sakharnym diabetom.