title: Prevention of intracranial problems in ear and sinus surgery: a possible role for cefotaxime.
abstract: Cases of intracranial sepsis of otorhinogenic origin presenting to a regional neurosurgical centre from 1984 to 1992 were examined with regard to their microbiology and antibiotic sensitivities. The results lead us to believe that cefotaxime may have a role in the initial ENT management of the potentially complicated case of ear or sinus sepsis.
authors.affiliation: Midland Centre for Neurosurgery and Neurology, Warley.
authors.forename: G M
authors.initials: GM
authors.lastname: Weiner
authors.forename: B
authors.initials: B
authors.lastname: Williams
mesh_terms: D001419:Bacteria / Q000187:drug effects; D001922:Brain Abscess / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D002439:Cefotaxime / Q000627:therapeutic use*; D002701:Chloramphenicol / Q000627:therapeutic use; D013354:Empyema, Subdural / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D010033:Otitis Media / Q000150:complications*; D010406:Penicillins / Q000627:therapeutic use; D012852:Sinusitis / Q000150:complications*
chemical_list: D010406:Penicillins; D008795:Metronidazole; D002701:Chloramphenicol; D002439:Cefotaxime