In situ hybridization study of kappa-opioid receptor mRNA in the rat brain.
Distribution of kappa-opioid receptor mRNA in rat brain was examined by in situ hybridization technique. kappa-Opioid receptor mRNA was expressed in various brain regions, especially intensely in the neocortex (layer V and VI), caudate-putamen, nucleus accumbens, preoptic area, paraventricular thalamic nucleus, amygdala, several nuclei of hypothalamus, ventral tegmental area and substantia nigra pars compacta.
Minami
M
M
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
Hosoi
Y
Y
Toya
T
T
Katao
Y
Y
Maekawa
K
K
Katsumata
S
S
Yabuuchi
K
K
Onogi
T
T
Satoh
M
M
D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D000818:Animals; D001345:Autoradiography; D001923:Brain Chemistry / Q000502:physiology*; D004399:Dynorphins / Q000494:pharmacology; D017403:In Situ Hybridization; D011759:Pyrrolidines / Q000494:pharmacology; D015347:RNA Probes; D016372:RNA, Antisense / Q000096:biosynthesis; D012333:RNA, Messenger / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D017473:Receptors, Opioid, kappa / Q000096:biosynthesis*
D011759:Pyrrolidines; D015347:RNA Probes; D016372:RNA, Antisense; D012333:RNA, Messenger; D017473:Receptors, Opioid, kappa; D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D004399:Dynorphins