title: Management of early oral cavity cancer. Experience of Centre Oscar Lambret.
abstract: From 1974 to 1983, 579 patients presenting with early oral cancer (excluding lip tumours) were treated at Centre Oscar Lambret. Of these, 429 were treated locally by brachytherapy with local control achieved in 82% of the cases (90% after salvage surgery). Treatment-related complications occurred in 19% of the cases, requiring surgical management in 13 patients. In contrast, only 51% of the 35 patients treated by external radiotherapy and brachytherapy were controlled, resulting in a poor 5-year survival (14%). Results for the 24 patients treated surgically were similar to those of brachytherapy alone. Finally, for T1 T2 N0 patients, the advantages of an elective neck dissection are not clear and could be clarified by a randomised trial. Indeed, this retrospective study failed to find a significant difference in the incidence of death due to an uncontrolled neck evolution whatever the neck management.
authors.affiliation: Department of Head and Neck Surgery, Centre Oscar Lambret, Lille, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Lefebvre
authors.forename: B
authors.initials: B
authors.lastname: Coche-Dequeant
authors.forename: E
authors.initials: E
authors.lastname: Buisset
authors.forename: X
authors.initials: X
authors.lastname: Mirabel
authors.forename: J T
authors.initials: JT
authors.lastname: Van
authors.forename: B
authors.initials: B
authors.lastname: Prevost
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000009:adverse effects; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D012189:Retrospective Studies; D016879:Salvage Therapy