title: Ergot induced peripheral vascular insufficiency, non-interventional treatment.
abstract: We report a case of ergotamine tartrate induced severe vasospasm in the renal arteries and the arteries of the lower extremities. Classic features seen on peripheral angiography make the diagnosis. Anticoagulation, thrombolysis, vasodilation, steroids, and prostaglandin inhibitors all have been successfully used to treat symptomatic ergot induced arterial vasospasm. Although balloon angioplasty of ergot induced vasospasm has been described in case reports, ergot vasospasm is a self limited and medically treatable condition that does not require peripheral mechanical intervention, unless the immediate threat of necrosis and gangrene exists.
authors.affiliation: Department of Medicine, Loyola University Medical Center, Maywood 60153.
authors.forename: T L
authors.initials: TL
authors.lastname: McKiernan
authors.forename: K
authors.initials: K
authors.lastname: Bock
authors.forename: F
authors.initials: F
authors.lastname: Leya
authors.forename: E
authors.initials: E
authors.lastname: Grassman
authors.forename: B
authors.initials: B
authors.lastname: Lewis
authors.forename: S A
authors.initials: SA
authors.lastname: Johnson
authors.forename: P J
authors.initials: PJ
authors.lastname: Scanlon
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D001158:Arteries / Q000187:drug effects; D004878:Ergotamine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008881:Migraine Disorders / Q000188:drug therapy; D016491:Peripheral Vascular Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000187:drug effects*
chemical_list: D000701:Analgesics, Opioid; D000925:Anticoagulants; D004878:Ergotamine