Non-endoscopic method to obtain Helicobacter pylori for culture.
A sampling method to collect samples for Helicobacter pylori culture that is easier than endoscopy would be useful. We used a capsule attached to a highly absorbent nylon string, which is swallowed to obtain gastric secretions. Antral biopsy and string specimens, sequentially obtained from 36 adults with clinically suspected ulcer or gastric disease were cultured. 9 (25%) patients were negative in both tests; 18 (50%) were positive by both methods; 6 (17%) were biopsy positive and string-test negative; and 3 (8%) were biopsy negative and string-test positive. The new test is useful, simple, and causes little discomfort.
Perez-Trallero
E
E
Servicio de Microbiologia, Facultad de Medicina, Hospital NS Aránzazu, San Sebastián, Spain.
Montes
M
M
Alcorta
M
M
Zubillaga
P
P
Telleria
E
E
D000328:Adult; D001706:Biopsy / Q000379:methods; D016099:Endoscopy, Gastrointestinal / Q000379:methods; D005750:Gastric Juice / Q000382:microbiology; D005753:Gastric Mucosa / Q000378:metabolism; D005756:Gastritis / Q000382:microbiology*; D016481:Helicobacter Infections / Q000382:microbiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D010437:Peptic Ulcer / Q000382:microbiology*; D011446:Prospective Studies; D013048:Specimen Handling / Q000379:methods*