title: Evidence for an age-dependent decrease in the immunoreactive prolactin-containing terminals of the median eminence of male rats.
abstract: Labelling patterns of immunoreactive prolactin (IR-PRL)-containing and tyrosine hydroxylase (TH)-containing nerve terminals of the median eminence (ME) were compared in young adult (aged 3 months) and old (aged 24 months) male Wistar rats. In the young rats, IR-PRL- and TH-immunostained fibres extended throughout the external most layer of the ME. In the old rats, a significant decrease in the intensity of labelling of IR-PRL terminals was observed in this layer, with a slight reduction in the extent of labelling. As far as TH terminals were concerned, no difference could be detected between young and old animals.
authors.affiliation: Endocrinological Neurobiology Laboratory, URA 1197 CNRS, University of Montpellier II, France.
authors.forename: P
authors.initials: P
authors.lastname: Siaud
authors.forename: G
authors.initials: G
authors.lastname: Barbanel
authors.forename: L
authors.initials: L
authors.lastname: Givalois
authors.forename: M J
authors.initials: MJ
authors.lastname: Reymond
authors.forename: M
authors.initials: M
authors.lastname: Balmefrézol
authors.forename: I
authors.initials: I
authors.lastname: Assenmacher
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D008473:Median Eminence / Q000378:metabolism*; D009411:Nerve Endings / Q000378:metabolism; D011388:Prolactin / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
chemical_list: D011388:Prolactin; D014446:Tyrosine 3-Monooxygenase