Continuous administration of dopamine alters cellular immunity in chickens.
Dopamine administered continuously through osmotic pumps altered the PHA wattle response and in vitro leukocyte capillary tube migration in UNH 105 chickens. The PHA wattle response was suppressed significantly by 48 hr exposure to dopamine at a dose of 1 microgram/hr. Administration of 10 micrograms/hr dopamine for 48 hr enhanced significantly in vitro leukocyte migration.
McCorkle
F M
FM
Department of Biology, Central Michigan University, Mt Pleasant 48859.
Taylor
R L
RL
D000818:Animals; D002464:Cell Migration Inhibition; D002645:Chickens / Q000276:immunology*; D004298:Dopamine / Q000008:administration & dosage / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D007111:Immunity, Cellular / Q000187:drug effects; D007260:Infusion Pumps; D007962:Leukocytes / Q000187:drug effects* / Q000276:immunology; D008297:Male; D009995:Osmosis; D010835:Phytohemagglutinins / Q000378:metabolism
D010835:Phytohemagglutinins; D004298:Dopamine