Screening and surgical intervention in the multiple endocrine neoplasia patient.
Persons with multiple endocrine neoplasias (MEN) are a unique group of patients that present with various APUDomas. Screening of family members can lead to early detection of these tumors and possible cure of potentially fatal tumors. Screening for the MEN syndromes at present is limited to provocative and biochemical parameters. The gene(s) responsible for these syndromes have not, as of yet, been characterized but in the future will add greatly to the ability to identify these patients early. Early surgical intervention of these APUDomas, has lead to an improved prognosis for these tumors. The screening and the surgical approach to each syndrome are outlined.
Pasieka
J L
JL
Department of Surgery, University of Calgary, Alberta, Canada.
D000328:Adult; D001079:Apudoma / Q000517:prevention & control* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D009377:Multiple Endocrine Neoplasia / Q000517:prevention & control* / Q000601:surgery*