title: Genetic polymorphism of the single locus probes pL159-1 and pL355-8.
abstract: The genetic polymorphism of the single-locus probes pL159-1 (D18S17) and pL355-8 (D20S15) was investigated in 445 unrelated individuals using PstI as restriction enzyme. Fragment size calculations were obtained using the molecular weight size marker MW-SBH. The basic relationship between migration distance and molecular weight was transformed using an exponential function. Fragment size frequency data show 2 peaks for pL159-1 at 4.36kb (2.36%) and 4.67 kb (6.29%) and one peak for pL355-8 at 6.04 kb (5.73%). The rate of heterozygosity exceeded 70% for both probes.
authors.affiliation: Institut für Anthropologie und Humangenetik, Tübingen, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Pfaff
authors.forename: C
authors.initials: C
authors.lastname: Luckenbach
authors.forename: H
authors.initials: H
authors.lastname: Ritter
mesh_terms: D000483:Alleles; D015342:DNA Probes; D005787:Gene Frequency; D006580:Genetic Carrier Screening; D005858:Germany; D006801:Humans; D008970:Molecular Weight; D009154:Mutation; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D015342:DNA Probes