title: [The impact of reproductive loss for human fertility. Results of the German part of a European study of the epidemiology of infertility and subfertility].
abstract: Within the German part of an European Community study of the epidemiology of infertility and subfecundity we analysed the fetal loss (i.e. spontaneous abortions, artificial abortions, ectopic pregnancies, stillbirth, early neonatal death and all babies who died after the 7th day within the first year of life). For this investigation women from 5 urban and rural regions in Germany in the age group 25-45 years were selected in five districts from random samples of the local registers. 1531 interviews were conducted in 1992 by trained female interviewers in the same way as in the other participating European countries. 1248 of the women had a positive reproductive anamnesis with 3018 pregnancies. 565 (= 45.3% of women who were pregnant at any time) had fetal loss. In East Germany as well as in West Germany we found a positive age and pregnancy association. The main loss we observed in the age group under 20 and over 35 years. In all groups artificial abortion was the most important part of fetal loss (rural region of East Germany: 15.5% and West Germany: 13.1% of all registered pregnancies). The time to pregnancy (TTP) was prolonged in women over 30 years of age. Here we also found an increasing rate of spontaneous abortions. Smokers are more prevalent in women with ectopic pregnancies, spontaneous abortions and live born babies who died within the first 7 days after delivery.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Medizinische Fakultät, Institut für Gesundheitswissenschaften, Universität Rostock.
authors.forename: H G
authors.initials: HG
authors.lastname: Neumann
authors.forename: U
authors.initials: U
authors.lastname: Dässler
authors.forename: W
authors.initials: W
authors.lastname: Karmaus
authors.forename: M
authors.initials: M
authors.lastname: Küppers-Chinnow
authors.forename: C
authors.initials: C
authors.lastname: Helfferich
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology* / Q000209:etiology; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D005313:Fetal Death / Q000453:epidemiology* / Q000209:etiology; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007246:Infertility / Q000453:epidemiology* / Q000209:etiology; D008875:Middle Aged; D011247:Pregnancy; D012307:Risk Factors
vernacular_title: Die Bedeutung reproduktiver Verluste für die menschliche Fertilität. Ergebnisse aus dem deutschen Teil einer europäischen Studie zur Epidemiologie von Infertilität und Subfekundität.