Capacity of a model immune network.
The capacity of a model immune network in terms of the number of different antigens that can be vaccinated against without any memory lost is computed and tested by numerical simulations. We also investigate memory loss and failure to vaccinate due to overcrowding the network with too many antigens. The computations are done for two different strategies for proliferation, one implying all the antigen specific clones and the second one being more thrifty.
Weisbuch
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Santa Fe Institute Suite A, NM 87501.
Oprea
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D000818:Animals; D017951:Antigen Presentation; D006801:Humans; D007107:Immune System / Q000502:physiology*; D007156:Immunologic Memory; D008213:Lymphocyte Activation; D008433:Mathematics; D008954:Models, Biological; D014611:Vaccination