Poly(ADP-ribose): historical perspective.
The early historical background of the discovery of poly(ADP-ribose) and the following development of science on poly(ADP-ribose) are reviewed. Fundamental knowledge on the natures of poly(ADP-ribose), poly(ADP-ribose) polymerase and enzymes degrading poly(ADP-ribose) are summarized with brief description on the methodology for their purification and characterization. Future prospect of research on biological significance of poly(ADP-ribose) has also been discussed briefly.
Sugimura
T
T
National Cancer Center, Tokyo, Japan.
Miwa
M
M
D049673:History, 20th Century; D015394:Molecular Structure; D011064:Poly Adenosine Diphosphate Ribose / Q000737:chemistry / Q000266:history*
D011064:Poly Adenosine Diphosphate Ribose