Mechanisms of pyrimethamine resistance in two different strains of Plasmodium berghei.
van Dijk
M R
MR
Laboratory for Parasitology, University of Leiden, The Netherlands.
McConkey
G A
GA
Vinkenoog
R
R
Waters
A P
AP
Janse
C J
CJ
D000595:Amino Acid Sequence; D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004351:Drug Resistance / Q000235:genetics; D005493:Folic Acid Antagonists; D017125:Genes, Protozoan; D008969:Molecular Sequence Data; D009097:Multienzyme Complexes / Q000037:antagonists & inhibitors / Q000235:genetics; D010962:Plasmodium berghei / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics*; D016788:Plasmodium chabaudi / Q000201:enzymology / Q000235:genetics; D010963:Plasmodium falciparum / Q000201:enzymology / Q000235:genetics; D017354:Point Mutation; D011739:Pyrimethamine / Q000494:pharmacology*; D017386:Sequence Homology, Amino Acid; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors / Q000235:genetics
D005493:Folic Acid Antagonists; D009097:Multienzyme Complexes; C056930:thymidylate synthase-dihydrofolate reductase; D013762:Tetrahydrofolate Dehydrogenase; D013940:Thymidylate Synthase; D011739:Pyrimethamine