Oral verrucous carcinoma: report of two cases and review of literature.
Verrucous carcinoma is a rare and distinct pathological and clinical variant of well-differentiated squamous cell carcinoma. Two case reports of histologically proven oral verrucous carcinoma are presented. One case presented with a history of tobacco chewing, snuff taking and miraa chewing. While the relationship between tobacco chewing or snuff dipping and verrucous carcinoma has been investigated and described, the role played by miraa chewing is still unknown and thus requires further study. Both cases were successfully managed by only conservative surgical excision. No radiotherapy was used. Clinical and histo-pathological examination of verrucous carcinoma is therefore very important in its diagnosis and treatment planning.
Awange
D O
DO
Department of Dental Surgery, College of Health Sciences, University of Nairobi, Kenya.
Onyango
J F
JF
D000328:Adult; D018289:Carcinoma, Verrucous / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D029754:Catha; D000697:Central Nervous System Stimulants / Q000009:adverse effects; D002610:Cheek; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D010936:Plant Extracts / Q000009:adverse effects; D010947:Plants, Toxic; D014030:Tobacco, Smokeless / Q000009:adverse effects; D014062:Tongue Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery
D000697:Central Nervous System Stimulants; D010936:Plant Extracts