title: Assignment of the linkage group EAM-TYRP2-TPP2 to chromosome 11 in pigs by in situ hybridization mapping of the TPP2 gene.
abstract: Restriction fragment length polymorphisms are described for the genes coding for tripeptidyl peptidase II (TPP2) and tyrosinase related protein II (TYRP2) in pigs. A linkage group comprising these loci and the locus for blood group M (EAM) was established by two-point lod score analysis in a three-generation pedigree. Multipoint analysis indicated the linear order EAM-1.1-TYRP2-8.4-TPP2 (recombination distances are given as Kosambi cM). The linkage group was assigned to porcine chromosome 11--the first on this chromosome--through in situ hybridization mapping of the TPP2 gene. TPP2 is the first gene localized on this chromosome using in situ hybridization.
authors.affiliation: Department of Animal Breeding and Genetics, Swedish Agricultural University, Uppsala.
authors.forename: B P
authors.initials: BP
authors.lastname: Chowdhary
authors.forename: M
authors.initials: M
authors.lastname: Johansson
authors.forename: F
authors.initials: F
authors.lastname: Gu
authors.forename: P
authors.initials: P
authors.lastname: Bräuner-Nielsen
authors.forename: B
authors.initials: B
authors.lastname: Tomkinson
authors.forename: L
authors.initials: L
authors.lastname: Andersson
authors.forename: I
authors.initials: I
authors.lastname: Gustavsson
mesh_terms: D000626:Aminopeptidases; D000818:Animals; D001789:Blood Group Antigens / Q000235:genetics; D002874:Chromosome Mapping; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D005260:Female; D008040:Genetic Linkage; D017403:In Situ Hybridization; D019746:Intramolecular Oxidoreductases; D007535:Isomerases / Q000235:genetics; D008297:Male; D012150:Polymorphism, Restriction Fragment Length; D012697:Serine Endopeptidases / Q000235:genetics*; D013552:Swine / Q000235:genetics*
chemical_list: D001789:Blood Group Antigens; D000626:Aminopeptidases; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; C048001:tripeptidyl-peptidase 2; D012697:Serine Endopeptidases; D007535:Isomerases; D019746:Intramolecular Oxidoreductases; C042501:dopachrome isomerase