title: [The dynamics of the morphological liver changes in primary biliary cirrhosis (based on the data from repeat biopsies)].
abstract: Repeat biopsy examinations (38 specimens) from 18 patients with primary biliary cirrhosis (PBC) showed association of the most active PBC with pronounced ductule proliferation, especially with ductule necrosis. The semiquantitative R. Knodell technique allows defining most characteristic histological parameters and correlations. In 3 patients the biopsies helped detect a combination of PBC with viral hepatitis resultant in cirrhosis. Repeat biopsies contribute to specification of the initial diagnosis, to evaluation of PBC activity and progression.
authors.forename: A S
authors.initials: AS
authors.lastname: Loginov
authors.forename: L I
authors.initials: LI
authors.lastname: Aruin
authors.forename: S D
authors.initials: SD
authors.lastname: Shepeleva
authors.forename: V D
authors.initials: VD
authors.lastname: Tkachev
mesh_terms: D000328:Adult; D001706:Biopsy; D002779:Cholestasis / Q000473:pathology; D002908:Chronic Disease; D018450:Disease Progression; D006521:Hepatitis, Chronic / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D008099:Liver / Q000473:pathology*; D008105:Liver Cirrhosis, Biliary / Q000473:pathology*; D008875:Middle Aged; D009336:Necrosis; D013997:Time Factors
vernacular_title: Dinamika morfologicheskikh izmeneniĭ pecheni pri pervichnom biliarnom tsirroze (po materialam povtornykh biopsiĭ).