title: [The role of eradication of Helicobacter pylori in healing and recurrence of gastric ulcer].
abstract: It is now generally accepted that infection with Helicobacter pylori is the most common cause of active chronic gastritis and duodenal ulceration. Although H. pylori is detected in the majority of patients with gastric ulcer, its pathogenicity and role in gastric ulceration remains unclear. One method to study this relationship is to eradicate H. pylori and observe the recurrence of gastric ulcer. In the present paper we examined the consequence of H. pylori eradication by antibiotics mono therapy with histamine H2 receptor antagonist on the recurrence of gastric ulcer. Two cases treated with proton pump inhibitor plus clarithromycin were reported. It is concluded that eradication of H. pylori infection may diminish the recurrence of gastric ulcers.
authors.affiliation: Department of Internal Medicine 4, Hyogo College of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Fukuda
authors.forename: I
authors.initials: I
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Tonokatsu
authors.forename: T
authors.initials: T
authors.lastname: Shimoyama
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016481:Helicobacter Infections / Q000188:drug therapy; D016480:Helicobacter pylori / Q000187:drug effects*; D006635:Histamine H2 Antagonists / Q000008:administration & dosage; D006801:Humans; D008297:Male; D012008:Recurrence; D013276:Stomach Ulcer / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D006635:Histamine H2 Antagonists