Cardiomyopathy induced by phenylpropanolamine.
A 14-year-old girl had evidence of an acute cardiomyopathy after a minimal overdose of phenylpropanolamine. She had myocardial dysfunction, ventricular dysrhythmia, and secondary pulmonary edema without any associated systemic hypertension. The cardiomyopathy resolved after several days.
Chin
C
C
Division of Pediatric Cardiology, University of California Davis Medical Center, Sacramento 95817.
Choy
M
M
D000293:Adolescent; D001977:Brompheniramine / Q000506:poisoning*; D009202:Cardiomyopathies / Q000139:chemically induced*; D004338:Drug Combinations; D062787:Drug Overdose; D005260:Female; D006634:Histamine H1 Antagonists / Q000506:poisoning*; D006801:Humans; D010656:Phenylephrine / Q000506:poisoning*; D010665:Phenylpropanolamine / Q000506:poisoning*; D054199:Pseudoephedrine
D004338:Drug Combinations; D006634:Histamine H1 Antagonists; C007484:brompheniramine, pseudoephedrine drug combination; D010656:Phenylephrine; D010665:Phenylpropanolamine; D054199:Pseudoephedrine; D001977:Brompheniramine