Highly informative compound haplotypes for the human Y chromosome.
A collection of polymorphic DNA sequences has been used to analyse the variability of a panel of 91 Y chromosomes. Some sequences (DYZ1 and DYZ2) were highly polymorphic and allowed all of the chromosomes to be distinguished. Other sequences were less polymorphic and were used to construct a haplotype for each chromosome and to assign chromosomes to groups. The best understood of these loci could be used to construct a tree showing the evolutionary relationships between the groups of Y chromosomes. In general, Y chromosomes from different ethnic backgrounds belong to different groups.
Mathias
N
N
Department of Biochemistry, University of Oxford, UK.
Bayés
M
M
Tyler-Smith
C
C
D001483:Base Sequence; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics; D017931:DNA Primers; D015342:DNA Probes; D004276:DNA, Satellite / Q000235:genetics; D005006:Ethnicity / Q000235:genetics*; D005819:Genetic Markers; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D044469:Racial Groups / Q000235:genetics*; D015183:Restriction Mapping; D014998:Y Chromosome
D017931:DNA Primers; D015342:DNA Probes; D004276:DNA, Satellite; D005819:Genetic Markers; D004247:DNA