title: Craniofacial resection. An analysis of 73 cases.
abstract: OBJECTIVE
  To determine the morbidity and mortality associated with a large series of patients undergoing craniofacial resection at one institution. The series is also analyzed with respect to pathology, disease recurrence, and role of adjuvant therapy.
  
  
  METHODS
  Retrospective review with a mean follow-up of 3 years (range, 6 months to 8 years).
  
  
  METHODS
  Tertiary care, urban referral center.
  
  
  METHODS
  The study included 73 consecutive patients (39 male and 34 female). Ages ranged from 13 to 78 years with a mean of 53.1 years. All patients had benign or malignant tumors of the paranasal sinuses.
  
  
  METHODS
  Morbidity associated with craniofacial resection was categorized as follows: early (within 30 days of surgery) or late (> 30 days); neurologic, ocular, or infectious.
  
  
  RESULTS
  Overall morbidity rate was 63%, and the mortality rate was 2.7%. Of the patients who had complications develop, 26 had development of major morbidities and there were two mortalities. The most common complications were transient alteration in mental status (15 patients), diplopia (11 patients), cerebrospinal fluid leak (10 patients), and osteomyelitis of the frontal bone flap (eight patients).
  
  
  CONCLUSIONS
  Craniofacial resection is an effective surgical treatment for paranasal sinus tumors. The mortality rate is acceptable and morbidity appears directly related to experience with the procedure. Infectious complications were the most devastating.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Mount Sinai School of Medicine, New York, NY.
authors.forename: P J
authors.initials: PJ
authors.lastname: Catalano
authors.forename: C S
authors.initials: CS
authors.lastname: Hecht
authors.forename: H F
authors.initials: HF
authors.lastname: Biller
authors.forename: W
authors.initials: W
authors.lastname: Lawson
authors.forename: K D
authors.initials: KD
authors.lastname: Post
authors.forename: V
authors.initials: V
authors.lastname: Sachdev
authors.forename: C
authors.initials: C
authors.lastname: Sen
authors.forename: M L
authors.initials: ML
authors.lastname: Urken
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003399:Craniotomy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010255:Paranasal Sinus Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D012008:Recurrence; D012189:Retrospective Studies