Cytokines involved in intrathymic T cell development.
Cytokines play an important role in intrathymic T cell development. Over the past several years, genes of newly discovered cytokines have been cloned, and the respective recombinant proteins have become available for functional studies of T cell development. In this paper we have attempted to review the respective roles of interleukins 1, 2, 4, 6, and 7. Special emphasis was given to interleukin 7 which has been shown to play a key role in early T cell differentiation.
He
W
W
Institute of Immunology and Serology, University of Heidelberg, Germany.
Kabelitz
D
D
D000818:Animals; D002454:Cell Differentiation / Q000276:immunology; D002455:Cell Division / Q000276:immunology; D016207:Cytokines / Q000502:physiology*; D006801:Humans; D007378:Interleukins / Q000502:physiology*; D013601:T-Lymphocytes / Q000166:cytology*; D013950:Thymus Gland / Q000166:cytology*
D016207:Cytokines; D007378:Interleukins