title: Characterization of a cDNA encoding the beta-chain of baboon receptor glycoprotein GPIb.
abstract: A cDNA probe, encoding part of the baboon integrin polypeptide, GPIIb, was used to screen a cDNA library derived from baboon platelet polyadenylated mRNA. One cross-hybridizing clone was found to be 94% similar to a human cDNA encoding the beta-chain of the receptor for von Willebrand factor, a major component of the platelet-subendothelium attachment mechanism.
authors.affiliation: Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30322.
authors.forename: D J
authors.initials: DJ
authors.lastname: Hayzer
authors.forename: M
authors.initials: M
authors.lastname: Shoji
authors.forename: T M
authors.initials: TM
authors.lastname: Kim
authors.forename: M S
authors.initials: MS
authors.lastname: Runge
authors.forename: S R
authors.initials: SR
authors.lastname: Hanson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001792:Blood Platelets / Q000378:metabolism*; D004247:DNA / Q000097:blood / Q000235:genetics* / Q000302:isolation & purification; D015342:DNA Probes; D015723:Gene Library; D006801:Humans; D046911:Macromolecular Substances; D008969:Molecular Sequence Data; D010215:Papio; D010980:Platelet Membrane Glycoproteins / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D015342:DNA Probes; D046911:Macromolecular Substances; D010980:Platelet Membrane Glycoproteins; D004247:DNA