Assignment of the linkage group EAM-TYRP2-TPP2 to chromosome 11 in pigs by in situ hybridization mapping of the TPP2 gene.
Restriction fragment length polymorphisms are described for the genes coding for tripeptidyl peptidase II (TPP2) and tyrosinase related protein II (TYRP2) in pigs. A linkage group comprising these loci and the locus for blood group M (EAM) was established by two-point lod score analysis in a three-generation pedigree. Multipoint analysis indicated the linear order EAM-1.1-TYRP2-8.4-TPP2 (recombination distances are given as Kosambi cM). The linkage group was assigned to porcine chromosome 11--the first on this chromosome--through in situ hybridization mapping of the TPP2 gene. TPP2 is the first gene localized on this chromosome using in situ hybridization.
Chowdhary
B P
BP
Department of Animal Breeding and Genetics, Swedish Agricultural University, Uppsala.
Johansson
M
M
Gu
F
F
Bräuner-Nielsen
P
P
Tomkinson
B
B
Andersson
L
L
Gustavsson
I
I
D000626:Aminopeptidases; D000818:Animals; D001789:Blood Group Antigens / Q000235:genetics; D002874:Chromosome Mapping; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D005260:Female; D008040:Genetic Linkage; D017403:In Situ Hybridization; D019746:Intramolecular Oxidoreductases; D007535:Isomerases / Q000235:genetics; D008297:Male; D012150:Polymorphism, Restriction Fragment Length; D012697:Serine Endopeptidases / Q000235:genetics*; D013552:Swine / Q000235:genetics*
D001789:Blood Group Antigens; D000626:Aminopeptidases; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; C048001:tripeptidyl-peptidase 2; D012697:Serine Endopeptidases; D007535:Isomerases; D019746:Intramolecular Oxidoreductases; C042501:dopachrome isomerase