title: Oral albendazole in the management of extraocular cysticercosis.
abstract: Surgical removal of extraocular cysticerci is fraught with complications. The effect of oral albendazole in such cases has been evaluated in a randomised, controlled, clinical trial. Of 24 ultrasonographically diagnosed, and ELISA positive cases of extraocular cysticerci, 12 received oral albendazole 15 mg/kg once daily for 1 month, while the 12 controls received a placebo. Marked clinical improvement was seen in all the cases in the treatment group at 4 weeks, with collapse of the cyst at 6 weeks (75%), and complete disappearance at 3 months (100%). No clinical or ultrasonographical change was noted in the control group. A trial of medical management with oral albendazole merits consideration in cases of extraocular cysticerci.
authors.affiliation: Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi.
authors.forename: R
authors.initials: R
authors.lastname: Sihota
authors.forename: S G
authors.initials: SG
authors.lastname: Honavar
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D015766:Albendazole / Q000008:administration & dosage*; D002648:Child; D003551:Cysticercosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D015822:Eye Infections, Parasitic / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009915:Orbit / Q000000981:diagnostic imaging; D009916:Orbital Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000469:parasitology; D014463:Ultrasonography
chemical_list: D015766:Albendazole