title: Immunity to jellyfish venoms: suppression of venom-induced immune responses in ultraviolet B-irradiated mice.
abstract: Lymph node and spleen cells from mice immunized with sea nettle (Chrysaora quinquecirrha) venom exhibited a proliferative response after exposure to the homologous antigen or that of a related jellyfish, Physalia (Portuguese man-o'-war). Native venom was a more effective stimulant than heated, non-lethal venom. Ultraviolet light treatments administered to the skin either before or after venom sensitization suppressed the proliferative response of these internal immune cells.
authors.affiliation: Department of Dermatology, University of Maryland School of Medicine, Baltimore 21201.
authors.forename: S
authors.initials: S
authors.lastname: Miura
authors.forename: J W
authors.initials: JW
authors.lastname: Burnett
authors.forename: L
authors.initials: L
authors.lastname: Aurelian
mesh_terms: D000818:Animals; D003064:Cnidarian Venoms / Q000276:immunology*; D005260:Female; D007108:Immune Tolerance / Q000528:radiation effects*; D008198:Lymph Nodes / Q000166:cytology; D008213:Lymphocyte Activation / Q000528:radiation effects; D051379:Mice; D008807:Mice, Inbred BALB C; D013154:Spleen / Q000166:cytology; D014466:Ultraviolet Rays
chemical_list: D003064:Cnidarian Venoms