Constrictive pericarditis after sclerosing therapy with mitomycin C for malignant pericardial effusion: report of a case.
Malignant pericardial effusion with cardiac tamponade is a life-threatening oncological emergency. Pericardiocentesis with sclerosing therapy is a life-saving palliative treatment procedure. Because of the short life expectancy in these patients, pericardial constriction after pericardial sclerosing therapy has been rarely reported in the literature. We report a patient with malignant pericardial effusion and cardiac tamponade which was successfully controlled by intrapericardial mitomycin C instillation. This patient developed pericardial constriction six months after mitomycin C pericardial sclerosis. It should be noted that pericardial constriction may occur if a patient survives long enough after successful pericardial sclerosis.
Lin
M T
MT
Department of Internal Medicine, Chang-Hua Christian Hospital, Taiwan, R.O.C.
Yang
P C
PC
Luh
K T
KT
D002305:Cardiac Tamponade / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000009:adverse effects*; D010490:Pericardial Effusion / Q000628:therapy*; D010493:Pericarditis / Q000209:etiology*; D015911:Sclerotherapy / Q000009:adverse effects*
D016685:Mitomycin