title: [Manic-depressive psychosis and electroencephalogram].
abstract: The literature dealing with electroencephalogram (EEG) in manic-depressive psychosis is reviewed. It is concluded that although there are no specific EEG patterns in the psychosis, some reports suggest a predominance of the alpha activity and a heightened arousal response. From many studies on sleep and depression, it appears that the EEG sleep architecture in depression is characterized by reduced total sleep time, intermittent awakenings, decreased slow-wave sleep and shortened REM latency. In particular, shortened REM latency is important for diagnosis of primary depression. Furthermore, the meaning of abnormal EEGs reported in the psychosis is worth investigating. In order to make the pathophysiology of manic-depressive psychosis clearer, it is important to carry out a comprehensive research, including clinical, physiological, biochemical and molecular biological study.
authors.affiliation: Department of Psychiatry, University of Tsukuba.
authors.forename: T
authors.initials: T
authors.lastname: Hori
authors.forename: H
authors.initials: H
authors.lastname: Shiraishi
mesh_terms: D001714:Bipolar Disorder / Q000503:physiopathology* / Q000628:therapy; D004569:Electroencephalography; D006801:Humans; D018377:Neurotransmitter Agents / Q000378:metabolism; D012895:Sleep, REM / Q000502:physiology
chemical_list: D018377:Neurotransmitter Agents