title: Is there still a need for Tc-99m DMSA renal imaging?
abstract: Scintigraphy with Tc-99m MAG3 is, to date, the most commonly used technique for evaluating separate renal function (SRF). In this study, the performance of this technique is compared to Tc-99m DMSA. A total of 37 patients with various kidney disorders (12 children and 25 adults) underwent both Tc-99m DMSA and Tc-99m MAG 3 scintigraphy. In children and adults of normal weight the correlation coefficient between the two methods was 0.99 (P < 0.001), whereas in individuals who were more than 10% overweight according to Broca, or who had abnormal anatomical positions of the kidneys, the correlation coefficient was 0.82 (P < 0.05). Scintigraphy with Tc-99m DMSA was more accurate in renal parenchyma lesions. These results indicate that Tc-99m DMSA scintigraphy is preferable for the evaluation of SRF in patients who are more than 10% overweight, or have abnormal positions of the kidneys.
authors.affiliation: Department of Nuclear Medicine, University of Erlangen-Nuremberg, Federal Republic of Germany.
authors.forename: H J
authors.initials: HJ
authors.lastname: Bair
authors.forename: W
authors.initials: W
authors.lastname: Becker
authors.forename: G
authors.initials: G
authors.lastname: Schott
authors.forename: R H
authors.initials: RH
authors.lastname: Kühn
authors.forename: F
authors.initials: F
authors.lastname: Wolf
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D000075202:Contraindications; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging; D007223:Infant; D007668:Kidney / Q000000981:diagnostic imaging; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D004113:Succimer; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D017263:Technetium Tc 99m Mertiatide
chemical_list: D015609:Organotechnetium Compounds; D017263:Technetium Tc 99m Mertiatide; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D004113:Succimer