Fetus with features of Crane-Heise syndrome and aminopterin syndrome sine aminopterin (ASSAS).
A male fetus with multiple congenital abnormalities is reported. The parents of the fetus are consanguineous. There were unusual facial features, digital anomalies, cleft palate, a malformed tongue that prevented swallowing, absent clavicles and genital hypoplasia. The fetus had features suggestive of both Crane-Heise syndrome and aminopterin syndrome sine aminopterin (ASSAS), and may represent part of a spectrum of abnormalities including these conditions.
Barnicoat
A J
AJ
Institute of Child Health, University of London, UK.
Seller
M J
MJ
Bennett
C P
CP
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000196:embryology*; D000328:Adult; D000630:Aminopterin; D003241:Consanguinity; D005145:Face / Q000002:abnormalities*; D005147:Facial Bones / Q000002:abnormalities*; D005260:Female; D005313:Fetal Death; D006801:Humans; D008297:Male; D011247:Pregnancy; D011859:Radiography
D000630:Aminopterin