title: Treatment resistant depression in an Australian context. II: Outcome of a series of patients.
abstract: The clinical characteristics and treatment outcome of a series of 107 patients referred to a mood disorders unit with an episode of "treatment resistant" Major Depression are reviewed. Subjects were categorised by diagnosis (into melancholic and non-melancholic subtypes) and by adequacy of previous treatment. At subsequent review (mean period of 37.5 months) these patients were re-assessed both in terms of outcome and which treatments had been considered to be most effective. Forty one percent of the patient group were fully recovered and a further 43% were partially improved. Different treatments were considered effective for melancholic and non-melancholic sub-types.
authors.affiliation: Mood Disorders Unit, Prince Henry Hospital, Little Bay, New South Wales.
authors.forename: K
authors.initials: K
authors.lastname: Wilhelm
authors.forename: P
authors.initials: P
authors.lastname: Mitchell
authors.forename: A
authors.initials: A
authors.lastname: Sengoz
authors.forename: I
authors.initials: I
authors.lastname: Hickie
authors.forename: H
authors.initials: H
authors.lastname: Brodaty
authors.forename: P
authors.initials: P
authors.lastname: Boyce
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001315:Australia; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis / Q000628:therapy*; D004359:Drug Therapy, Combination; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D008297:Male; D008605:Mental Health Services / Q000458:organization & administration; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents