[Preanesthesia in elderly patients undergoing subarachnoid anesthesia: chlordesmethyldiazepam versus diazepam].
Forty patients over 65 undergoing subarachnoid anesthesia with bupivacaine 0.50% (5 mg) and fentanyl (0.1 mg) were subdivided into two equal groups: one was premedicated with atropine and chlordesmethyldiazepam (0.03 mg/kg-1) and the other with atropine and diazepam (0.015 mg/Kg-1). A statistically significant difference was found in the group treated with diazepam which required an increase for anesthetic drugs during surgery. The authors suggest a probable synergic or an enhanced effect between intramuscular chlordesmethyldiazepam and opiates in spinal anesthesia.
Ramella
G
G
Servizio di Anestesia e Rianimazione, Ospedale di Abbiategrasso, Milano.
Costagli
V
V
Sogni
A
A
Casella
G
G
Capra
C
C
D000368:Aged; D000775:Anesthesia, Spinal; D014151:Anti-Anxiety Agents / Q000009:adverse effects; D001569:Benzodiazepines; D003975:Diazepam / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D003708:Nordazepam / Q000009:adverse effects / Q000031:analogs & derivatives*; D011229:Preanesthetic Medication
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D003708:Nordazepam; C013434:chlordesmethyldiazepam; D003975:Diazepam
La preanestesia nei soggetti anziani sottoposti ad anestesia sub-aracnoidea: clordemetildiazepam vs diazepam.