[The cytochemical characteristics of the blood polymorphonuclear leukocytes in dilated cardiomyopathy and an inflammatory myocardial lesion].
Using methods of cytochemical investigation of the blood polymorphonuclear leucocytes (PMNL), parameters have been studied, characterizing the systems of biological defence and bioenergetics in patients with dilated cardiomyopathy (DCMP), infectious allergic myocarditis (IAM) and myocarditic cardiosclerosis (MCS). DCMP patients showed depression of NBT--test against the background of the increase in the cationic proteins (CP) level in the blood PMNLs, which was a major cytochemical feature. G-6-PhDG activity was increased in IAM patients against the background of high values of NBT-test. Increased values for G-6-PhDG, CP, phosphatases in the presence of low levels of myeloperoxidase in the blood PMNL suggest chronic inflammatory process in the myocardium. Investigation into the cytochemical parameters of bioenergetic and biological defence of the blood PMNL in patients with DCMP, IAM and MCS permits optimization of the diagnosis and treatment policy in the aforementioned nosological entities.
Mazurets
A F
AF
Kubyshkin
V F
VF
Dziuba
M V
MV
D000293:Adolescent; D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis*; D004796:Clinical Enzyme Tests; D004734:Energy Metabolism; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000175:diagnosis*; D009504:Neutrophils / Q000201:enzymology*; D009580:Nitroblue Tetrazolium
D009580:Nitroblue Tetrazolium
Tsitokhimicheskaia kharakteristika polimorfnoiadernykh leĭkotsitov krovi pri dilatsionnoĭ kardiomiopatii i vospalitel'nom porazhenii miokarda.