title: Sequence of the proteinase-inhibitor cystatin homologue from the pollen of Ambrosia artemisiifolia (short ragweed).
abstract: The nucleotide sequence of a cDNA (designated IPC1/5) encoding a cystatin (Cyt) proteinase-inhibitor homologue from short ragweed (Ambrosia artemisiifolia) pollen was determined and compared to other plant and animal Cyt. The absence of disulfide bonds in the predicted translation product of the IPC1/5 sequence suggests that it most resembles family-I members of the Cyt superfamily. Significant amino acid (aa) sequence identity was found when comparing the translated sequence of IPC1/5 to rice seed Cyt, human keratocyte Cyt A and human liver Cyt B.
authors.affiliation: ImmuLogic Pharmaceutical Corporation, Waltham, MA 02154.
authors.forename: B L
authors.initials: BL
authors.lastname: Rogers
authors.forename: J
authors.initials: J
authors.lastname: Pollock
authors.forename: D G
authors.initials: DG
authors.lastname: Klapper
authors.forename: I J
authors.initials: IJ
authors.lastname: Griffith
mesh_terms: D000485:Allergens / Q000235:genetics / Q000276:immunology; D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D015891:Cystatins / Q000235:genetics* / Q000276:immunology; D004247:DNA; D006801:Humans; D008969:Molecular Sequence Data; D010944:Plants / Q000235:genetics* / Q000276:immunology; D011058:Pollen / Q000737:chemistry / Q000276:immunology; D016133:Polymerase Chain Reaction; D017386:Sequence Homology, Amino Acid
chemical_list: D000485:Allergens; D015891:Cystatins; D004247:DNA