title: Synthesis, anticonvulsant and neuroprotective activities of RP 66055, a riluzole derivative.
authors.affiliation: Rhône-Poulenc Rorer S.A., Central Research, Centre de Recherche de Vitry-Alfortville, Vitry sur Seine, France.
authors.forename: P
authors.initials: P
authors.lastname: Jimonet
authors.forename: M
authors.initials: M
authors.lastname: Barreau
authors.forename: J C
authors.initials: JC
authors.lastname: Blanchard
authors.forename: A
authors.initials: A
authors.lastname: Boireau
authors.forename: A
authors.initials: A
authors.lastname: Doble
authors.forename: P
authors.initials: P
authors.lastname: Laduron
authors.forename: J
authors.initials: J
authors.lastname: Lavayre
authors.forename: C
authors.initials: C
authors.lastname: Malgouris
authors.forename: O
authors.initials: O
authors.lastname: Piot
authors.forename: J
authors.initials: J
authors.lastname: Pratt
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology*; D002545:Brain Ischemia / Q000517:prevention & control; D003342:Corpus Striatum / Q000187:drug effects / Q000378:metabolism; D004195:Disease Models, Animal; D004298:Dopamine / Q000378:metabolism; D005849:Gerbillinae; D002534:Hypoxia, Brain / Q000517:prevention & control; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D015394:Molecular Structure; D009420:Nervous System / Q000187:drug effects*; D051381:Rats; D011916:Rats, Inbred F344; D017207:Rats, Sprague-Dawley; D012640:Seizures / Q000517:prevention & control; D026941:Sodium Channel Blockers; D015222:Sodium Channels / Q000378:metabolism; D013844:Thiazoles / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D000927:Anticonvulsants; C089331:RP 66055; D026941:Sodium Channel Blockers; D015222:Sodium Channels; D013844:Thiazoles; D004298:Dopamine