The nucleotide and deduced amino acid sequences of a peptidyl-prolyl cis-trans isomerase from Arabidopsis thaliana.
The nucleotide sequence of a cDNA clone from Arabidopsis thaliana ecotype Columbia was determined, and the corresponding amino acid sequence deduced. The predicted sequence is highly homologous to those of members of the cyclophilin A-family of peptidyl-prolyl cis-trans isomerases. The tryptophan residue necessary for interaction with cyclosporin A is located at approximately the same position in the plant sequence as it is in mammalian sequences. The carboxy-terminus of the plant prolyl isomerase sequence contains a cryptic prenylation motif.
Hayman
G T
GT
Phytoproducts Research Unit, National Center for Agricultural Utilization Research, Peoria, IL 61604.
Miernyk
J A
JA
D000591:Amino Acid Isomerases / Q000235:genetics*; D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000201:enzymology*; D001483:Base Sequence; D002352:Carrier Proteins / Q000235:genetics*; D017343:Genes, Plant; D008969:Molecular Sequence Data; D019696:Peptidylprolyl Isomerase; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D002352:Carrier Proteins; D000591:Amino Acid Isomerases; D019696:Peptidylprolyl Isomerase