title: Cloning and characterization of genes encoding tetrahydrobiopterin biosynthetic enzymes.
authors.affiliation: William T. Gossett Neurology Laboratories, Henry Ford Hospital, Detroit, MI 48201.
authors.forename: R A
authors.initials: RA
authors.lastname: Levine
authors.forename: J C
authors.initials: JC
authors.lastname: States
authors.forename: P Z
authors.initials: PZ
authors.lastname: Anastasiadis
authors.forename: D M
authors.initials: DM
authors.lastname: Kuhn
mesh_terms: D000429:Alcohol Oxidoreductases / Q000096:biosynthesis*; D000818:Animals; D001708:Biopterins / Q000031:analogs & derivatives* / Q000096:biosynthesis; D015152:Blotting, Northern; D001921:Brain / Q000201:enzymology*; D003001:Cloning, Molecular / Q000379:methods; D003342:Corpus Striatum / Q000187:drug effects / Q000201:enzymology; D018076:DNA, Complementary / Q000378:metabolism; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects*; D007608:Kainic Acid / Q000633:toxicity; D020267:MPTP Poisoning; D008297:Male; D051379:Mice; D012333:RNA, Messenger / Q000032:analysis / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013378:Substantia Nigra / Q000187:drug effects / Q000201:enzymology; D014446:Tyrosine 3-Monooxygenase / Q000096:biosynthesis*
chemical_list: D018076:DNA, Complementary; D012333:RNA, Messenger; D001708:Biopterins; D000429:Alcohol Oxidoreductases; C022630:sepiapterin reductase; D014446:Tyrosine 3-Monooxygenase; C003402:sapropterin; D007608:Kainic Acid