title: An unreported RFLP for probe 218 EP6 that is useful in linkage analysis of adult polycystic kidney disease.
abstract: Probe 218 EP6 is known to recognise two restriction fragment length polymorphisms (RFLPs) after digestion of genomic DNA with PvuII. We report a rare allele that segregates in Mendelian fashion, in a family where adult polycystic kidney disease was being tracked using linked polymorphisms.
authors.affiliation: S.W. Thames Genetic Unit, St George's Hospital Medical School, London, UK.
authors.forename: S
authors.initials: S
authors.lastname: Jeffery
authors.forename: S
authors.initials: S
authors.lastname: Morgan
mesh_terms: D000483:Alleles; D002885:Chromosomes, Human, Pair 16; D004247:DNA / Q000032:analysis; D015342:DNA Probes; D005260:Female; D008040:Genetic Linkage / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D016891:Polycystic Kidney, Autosomal Dominant / Q000235:genetics*; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D015342:DNA Probes; D004247:DNA