Tinggong(SI 19), a novel acupoint for 2Hz electroacupuncture-induced depressor response.
In urethane-anesthetized, tubocurarine-immobilized and artificially ventilated rats, the specific electroacupuncture (EA, 2 Hz, 3 V) being delivered to bilateral "Tinggong (SI 19)-Quchi (LI 11)" induced a depressor response, while 10 Hz-EA, and 2 Hz-EA to either non-acupoints, "Hegu (LI 4)-Quchi" or "Taichong (Liv 3)-Quchi" did not. Pretreatment of either phentolamine, Propranolol or methyl atropine (i.v.) could markedly reduce the depressor response, indicating that the sympathetic vasoconstrictor nerve, the cardia sympathetic nerve and cardiac vagal nerve all are involved in the hypotensive response.
Ku
Y H
YH
Department of Physiology, Beijing Medical University, P.R. China.
Zou
C J
CJ
D015669:Acupuncture Points; D000818:Animals; D001286:Atropine Derivatives / Q000494:pharmacology; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000187:drug effects; D015671:Electroacupuncture / Q000379:methods*; D005069:Evaluation Studies as Topic; D006973:Hypertension / Q000628:therapy; D008297:Male; D010276:Parasympatholytics / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
D001286:Atropine Derivatives; D010276:Parasympatholytics; C006649:methylatropine; D011433:Propranolol; D010646:Phentolamine