Influence of insulin on the movement of Tetrahymena pyriformis. Hormonal imprinting alters the velocity.
Treatment with insulin, cyclic adenosine monophosphate (cAMP) or theophylline, which uniformly influence the intracellular cAMP level, accounted for appreciable changes in the movement of Tetrahymena pyriformis. All applied treatments caused a quantitative decrease in the percentage of relatively rapid movements (straight and spiral swimming) and a proportional increase in that of slow movements (standing, turn, creeping). A single treatment with insulin caused a quantitative decrease in fast movements and a quantitative increase in slow movements also in the offspring generations and reexposure to insulin had a similar, but even stronger effect.
Kovács
P
P
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
Lovas
G
G
Csaba
G
G
D000818:Animals; D002465:Cell Movement / Q000187:drug effects; D000242:Cyclic AMP / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology*; D013769:Tetrahymena pyriformis / Q000166:cytology / Q000187:drug effects*; D013806:Theophylline / Q000494:pharmacology
D007328:Insulin; D013806:Theophylline; D000242:Cyclic AMP