Epinephrine effects on gastrin and gastric secretions in normal and stress-susceptible pigs and in dogs.
1. Epinephrine induced plasma gastrin concentration increased linearly in dogs, and significantly in pigs. 2. Epinephrine induced gastric secretion rate increased in dogs and decreased in pigs, and yet significantly reduced gastric pH only in dogs. 3. Statistical differences in heart and respiratory rate with epinephrine versus saline infusion were detected only in pigs. 4. Stress-susceptible pigs had a significant decrease in gastric secretion pH, heart rate and increased respiration compared to normal pigs, during saline infusion.
Marolf
C J
CJ
Department of Veterinary, University of Nebraska-Lincoln 68583.
Schultz
B D
BD
Clemens
E T
ET
D000818:Animals; D004285:Dogs; D004837:Epinephrine / Q000494:pharmacology*; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D005755:Gastrins / Q000187:drug effects* / Q000378:metabolism; D006339:Heart Rate / Q000187:drug effects; D006863:Hydrogen-Ion Concentration / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D013312:Stress, Physiological / Q000503:physiopathology*; D013552:Swine
D005755:Gastrins; D004837:Epinephrine