The visualization of granulomatous disease with somatostatin receptor scintigraphy.
In-111 labeled pentetreotide scintigraphy was applied to three patients with proven granulomatous disease (two with sarcoidosis, one with tuberculosis). All revealed accumulation of In-111 labeled pentetreotide in the granulomatous lesions, which was considered to be due to the presence of activated lymphocytes in these regions. This method may be of value in assessing the activity and extent of sarcoidosis and tuberculosis.
Oztürk
E
E
Gülhane Military Medical Academy, Ankara, Turkey.
Günalp
B
B
Ozgüven
M
M
Ozkan
S
S
Sipit
T
T
Narin
Y
Y
Bayhan
H
H
D000328:Adult; D001402:B-Lymphocytes / Q000378:metabolism; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D017481:Receptors, Somatostatin / Q000378:metabolism; D012507:Sarcoidosis / Q000000981:diagnostic imaging*; D017565:Sarcoidosis, Pulmonary / Q000000981:diagnostic imaging*; D013004:Somatostatin / Q000031:analogs & derivatives*; D013601:T-Lymphocytes / Q000378:metabolism; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging*
D007205:Indium Radioisotopes; D017481:Receptors, Somatostatin; D013004:Somatostatin; C081788:pentetreotide