title: Identification of the 5' end of the gene encoding a human insulin-responsive glucose transporter.
abstract: The 5' end of a gene (GLT4) encoding a human insulin-responsive glucose transporter was isolated from a human lambda Fix genomic library and sequenced. The human sequence, as compared to the mouse GLT4 promoter [Kaestner et al., Proc. Natl. Acad. Sci. USA 87 (1990) 251-255], revealed an overall homology of 81%. Putative transcription controlling sequences were identified.
authors.affiliation: Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi di Milano, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Chiaramonte
authors.forename: R
authors.initials: R
authors.lastname: Martini
authors.forename: R
authors.initials: R
authors.lastname: Taramelli
authors.forename: P
authors.initials: P
authors.lastname: Comi
mesh_terms: D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA; D005091:Exons; D051275:Glucose Transporter Type 4; D006801:Humans; D007438:Introns; D051379:Mice; D008969:Molecular Sequence Data; D009004:Monosaccharide Transport Proteins / Q000235:genetics*; D009124:Muscle Proteins; D011401:Promoter Regions, Genetic; D012689:Sequence Homology, Nucleic Acid
chemical_list: D051275:Glucose Transporter Type 4; D009004:Monosaccharide Transport Proteins; D009124:Muscle Proteins; C495692:SLC2A4 protein, human; C495693:Slc2a4 protein, mouse; D004247:DNA