Serum prolactin levels in postpill amenorrheic patients.
OBJECTIVE
In this study, we evaluated the importance of the determination of serum prolactin levels in postpill amenorrheic patients.


METHODS
Serum estradiol and prolactin levels were determined in 37 postpill amenorrheic patients. Bromocriptine was administered to the hyperprolactinemic group and clomiphene citrate to the normoprolactinemic group.


RESULTS
Hyperprolactinemia was observed in 21 patients (56.7%) and serum estradiol levels < 50 pg/ml were found in 19 of these patients. The mean prolactin level was 71.90 +/- 23.05 ng/ml in the hyperprolactinemic group. While bromocriptine had a significant effect on the length of time for menstrual bleeding to return (P < 0.001), clomifene had no effect.


CONCLUSIONS
No treatment is required for the postpill amenorrheic patients with normal estradiol and prolactin levels. If hyperprolactinemia is detected, bromocriptine may be used as a treatment to promote normal menstrual bleeding and ovulation.
Karaman
A S
AS
Department of Obstetrics and Gynecology, Social Security Hospital, Kütahya, Turkey.
Uran
B
B
Erler
A
A
D000328:Adult; D000568:Amenorrhea / Q000097:blood* / Q000139:chemically induced; D001971:Bromocriptine / Q000494:pharmacology; D003276:Contraceptives, Oral / Q000009:adverse effects; D004958:Estradiol / Q000097:blood; D005260:Female; D005687:Galactorrhea / Q000097:blood; D006801:Humans; D008598:Menstruation / Q000187:drug effects; D011388:Prolactin / Q000097:blood*
D003276:Contraceptives, Oral; D001971:Bromocriptine; D004958:Estradiol; D011388:Prolactin