title: Viral implications in the formation of multicentric inverting papilloma.
abstract: There is growing information to support a viral etiology in inverting papilloma formation. Evidence for this hypothesis comes from clinical findings of multicentricity, high recurrence rates, identification of human papilloma virus (HPV), and the presence of viral-like particles within the tumour tissue. Four cases of multicentric inverting papilloma are presented. In one patient, a squamous papilloma (wart) of the nasal vestibule recurred as an inverting papilloma. Another patient also had a cutaneous wart on the right index finger. These cases and others from the literature are discussed with respect to a viral mode of transmission.
authors.affiliation: Department of Otolaryngology, McGill University Faculty of Medicine, SMBD-Jewish General Hospital, Montreal, Quebec.
authors.forename: S
authors.initials: S
authors.lastname: Frenkiel
authors.forename: F D
authors.initials: FD
authors.lastname: Mongiardo
authors.forename: T L
authors.initials: TL
authors.lastname: Tewfik
authors.forename: M
authors.initials: M
authors.lastname: Mendelsohn
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D053685:Laser Therapy; D008297:Male; D009300:Nasal Septum / Q000473:pathology / Q000601:surgery / Q000821:virology*; D018308:Papilloma, Inverted / Q000473:pathology / Q000601:surgery / Q000821:virology*; D027383:Papillomaviridae / Q000302:isolation & purification*