Episodic tardive dyskinesia and parkinsonism in bipolar disorder patients.
Three cases of rapid cycling bipolar patients manifesting episodic parkinsonism are described. Moderate to severe parkinsonism and tardive dyskinesia appeared in all three of these patients before the onset of depression, then worsened during depression and disappeared during mania. A possible mechanism for this phenomenon is hypothesized.
Scappa
S
S
King-Drew Medical Center, Los Angeles, California.
Teverbaugh
P
P
Ananth
J
J
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D004298:Dopamine / Q000502:physiology; D004359:Drug Therapy, Combination; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D016651:Lithium Carbonate / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D012008:Recurrence
D014150:Antipsychotic Agents; D016651:Lithium Carbonate; D004298:Dopamine