title: Regulation of gene expression by cofactors derived from B vitamins.
abstract: Vitamins represent precursor molecules for the majority of cofactors essential for various enzyme activities. Is the expression of proteins that require a specific cofactor for their function correlated to its availability? Examples are presented and discussed of the involvement of vitamin-derived cofactors in the regulatory mechanisms controlling gene expression in bacteria and eukaryotes at the transcriptional and translational level.
authors.affiliation: Biochemisches Institut, Universität Freiburg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Brandsch
mesh_terms: D000818:Animals; D001419:Bacteria / Q000235:genetics; D003067:Coenzymes / Q000378:metabolism / Q000494:pharmacology*; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism / Q000494:pharmacology; D005658:Fungi / Q000235:genetics; D005786:Gene Expression Regulation / Q000187:drug effects*; D014803:Vitamin B Complex / Q000378:metabolism*
chemical_list: D003067:Coenzymes; D014803:Vitamin B Complex; D005182:Flavin-Adenine Dinucleotide