title: L-leucine intestinal transport at different ages in chicken: effect of anticoccidial drugs.
abstract: 1. L-Leucine transport by everted slices of duodenum, jejunum ileum and cecum of 1-, 2- and 3-week-old chickens has been determined. 2. The effects of the administration with the diet of three anticoccidial drugs: monensin, maduromicin ammonium and nicarbazine have been studied. 3. In the control animals, there is a reduction on intestinal transport with age, except in the duodenum which is not age-dependent. 4. Momensine induces an increase on leucine transport in the duodenum and cecum at all ages studied and only in the 3-week-old animals in the jejunum and ileum. 5. Nicarbazine reduces jejunal absorption of leucine and does not affect the function of the other segments. 6. Maduromicin ammonium has almost no effect on the absorptive process.
authors.affiliation: Departament de Ciencies Fisiologiques Humanes i de la Nutrició, Facultat de Farmàcia, Barcelona, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Gonzalez
authors.forename: M P
authors.initials: MP
authors.lastname: Vinardell
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002645:Chickens; D003049:Coccidiostats / Q000494:pharmacology*; D004032:Diet; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000187:drug effects; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000187:drug effects; D007930:Leucine / Q000378:metabolism*; D008297:Male; D008954:Models, Biological
chemical_list: D003049:Coccidiostats; D007930:Leucine