A high recombination frequency within the chicken major histocompatibility (B) complex.
Chickens of a commercial pure White Leghorn line were typed for B-F and B-G by serological, biochemical and molecular biological methods. Amongst 287 typed animals of one particular line, three animals with recombinant haplotypes were identified. Compared to earlier reports this revealed a statistically significant (P < 0.05), tenfold higher recombination frequency in this chicken line.
Hepkema
B G
BG
Department of Immunology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands.
Tilanus
M G
MG
Blankert
H J
HJ
Albers
G A
GA
Grosfeld-Stulemeyer
M C
MC
Hensen
E J
EJ
D000818:Animals; D015153:Blotting, Western / Q000662:veterinary; D002645:Chickens / Q000235:genetics*; D015342:DNA Probes; D005260:Female; D005787:Gene Frequency; D006239:Haplotypes; D006386:Hemagglutination Tests / Q000662:veterinary; D008285:Major Histocompatibility Complex / Q000235:genetics*; D008297:Male; D012150:Polymorphism, Restriction Fragment Length; D011995:Recombination, Genetic
D015342:DNA Probes