title: [Surgical treatment of transposition of the great arteries with intact ventricular septum associated with left ventricular outflow obstruction].
abstract: Thirteen patients have undergone surgical treatment for transposition of the great arteries (TGA) with intact ventricular septum (IVS) associated with left ventricular outflow obstruction (LVOTO) in our institute. Ages at operation ranged from three months to six years (mean 9.2 +/- 4.7 months). Of these patients, seven had dynamic type LVOTO (group I), and six had organic LVOTO (group II). Preoperative left ventricular end-diastolic volume was significantly smaller in group II (78 +/- 13% of normal) than control group (135 +/- 53% of normal). Preoperative pressure gradient between the pulmonary artery and left ventricle was significantly greater in group II (55.8 +/- 3.2 mmHg) than group I (35.2 +/- 3.9 mmHg). In group I, II patients underwent two-stage ASO, the other 5 patients underwent Senning operation. The reason for the Senning operation were era before introduction of ASO in our institute (1983) or unsuccessful training of the left ventricle. In group II, all but one patient underwent Senning operation, the other underwent a successful Fontan operation with Damus anastomosis because of too small left ventricle (LVEDV: 49% of normal). Techniques to correct LVOTO at the definitive operation included ventriculotomy (n = 4) and pulmonary valvotomy (n = 2). One patients in group II underwent a Fontan operation with Damus anastomosis due to an underdeveloped left ventricle (LVEDV: 49% of normal). There was no early or late death. The postoperative pressure gradients disappeared or reduced to trivial levels in all patients. At present no LVOTO has developed in any of the patients.
authors.affiliation: Department of Pediatric Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Shin'oka
authors.forename: Y
authors.initials: Y
authors.lastname: Imai
authors.forename: S
authors.initials: S
authors.lastname: Hoshino
authors.forename: K
authors.initials: K
authors.lastname: Seo
authors.forename: M
authors.initials: M
authors.lastname: Terada
authors.forename: H
authors.initials: H
authors.lastname: Misumi
authors.forename: J
authors.initials: J
authors.lastname: Ohta
authors.forename: Y
authors.initials: Y
authors.lastname: Sugiyama
mesh_terms: D006348:Cardiac Surgical Procedures / Q000379:methods; D002675:Child, Preschool; D006346:Heart Septum; D006352:Heart Ventricles; D006801:Humans; D007223:Infant; D014188:Transposition of Great Vessels / Q000150:complications / Q000601:surgery*; D014694:Ventricular Outflow Obstruction / Q000150:complications*