[Disorders in the plasma and cellular hemostatic components of patients with HIV infection].
Plasmic and platelet components of hemostasis were investigated in 100 HIV-infected subjects. Its degree depended on the infection stage and associated opportunistic infections. The key factor in pathogenesis of hemocoagulatory disorders is reduced count, abnormal function and morphology of platelets. A direct relationship exists between the number of CD4-lymphocytes, a decline in the number and functional activity of platelets. Intravenous injection of immunoglobulin made in Russia as an adjuvant to combined therapy of HIV-infected subjects contributes to recovery of platelet count and aggregation.
Poliakova
A M
AM
Kravchenko
A V
AV
Astrina
O S
OS
Serebrovskaia
L V
LV
Iurin
O G
OG
Pokrovskiĭ
V V
VV
Maleev
V V
VV
D000936:Antigen-Antibody Complex / Q000097:blood; D001778:Blood Coagulation Disorders / Q000097:blood* / Q000276:immunology; D001792:Blood Platelets / Q000276:immunology; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000276:immunology; D015497:HIV-1; D006487:Hemostasis; D006801:Humans; D007111:Immunity, Cellular; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D010949:Plasma / Q000276:immunology
D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G
Narusheniia v plazmennom i kletochnom zvene gemostaza bol'nykh s VICh-infektsieĭ.