title: Mupirocin-resistant Staphylococcus aureus in a specialist school population.
abstract: Staphylococcus aureus strains resistant to mupirocin (MIC > 4000 mg l-1) were recovered from children and staff at a school for children with eczema and/or asthma or cystic fibrosis after mupirocin had been used to treat eczematous lesions. At least three distinct strains of S. aureus were involved and resistance was shown to be due in most isolates to a transmissible plasmid. The need for monitoring the extended use of this valuable antibiotic is emphasized.
authors.affiliation: Department of Microbiology, Eastbourne District General Hospital, East Sussex, UK.
authors.forename: C A
authors.initials: CA
authors.lastname: Chatfield
authors.forename: W A
authors.initials: WA
authors.lastname: O'Neill
authors.forename: R P
authors.initials: RP
authors.lastname: Cooke
authors.forename: K J
authors.initials: KJ
authors.lastname: McGhee
authors.forename: M
authors.initials: M
authors.lastname: Issack
authors.forename: M
authors.initials: M
authors.lastname: Rahman
authors.forename: W C
authors.initials: WC
authors.lastname: Noble
mesh_terms: D000293:Adolescent; D001249:Asthma; D001434:Bacteriophage Typing; D002353:Carrier State / Q000382:microbiology*; D002648:Child; D003550:Cystic Fibrosis; D004352:Drug Resistance, Microbial; D004485:Eczema; D005260:Female; D006801:Humans; D008297:Male; D016712:Mupirocin / Q000494:pharmacology*; D010957:Plasmids / Q000235:genetics; D012574:Schools; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D016712:Mupirocin; D013752:Tetracycline