Anatomical and clinical correlation with histological and histometric patterns in cryptorchism.
One feature rarely included in studies on cryptorchism is an adequate correlation between anatomical and clinical data and histological patterns of the testis. The present study correlates anatomical and clinical data from 50 patients (age range 2 months-14 years) using 4 different histological and histometric patterns established previously. Three different patterns of progressively severe histological changes corresponding to increasingly marked dysgenetic alterations in the anatomical and clinical patterns were detected. Less severe changes were correlated with mature anatomical and clinical features, whereas testes showing severe histological-histometric changes were correlated with immature anatomical and clinical features. Non-abdominally located testes with Sertoli cell hyperplasia were not significantly correlated with any of the anatomical and clinical features. The histometric patterns described should facilitate the diagnosis of the stage of testicular development on the basis of anatomical and clinical data.
Gutierrez
A
A
Department of Histology and Cell Biology, University of Granada, Spain.
Campos
A
A
Cañizares
F J
FJ
Crespo
P V
PV
Sánchez
C
C
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000209:etiology / Q000473:pathology*; D004822:Epididymis / Q000473:pathology; D006801:Humans; D007223:Infant; D007264:Inguinal Canal / Q000473:pathology; D008297:Male; D012708:Sertoli Cells / Q000473:pathology; D013737:Testis / Q000473:pathology*