Genetic polymorphism of the single locus probes pL159-1 and pL355-8.
The genetic polymorphism of the single-locus probes pL159-1 (D18S17) and pL355-8 (D20S15) was investigated in 445 unrelated individuals using PstI as restriction enzyme. Fragment size calculations were obtained using the molecular weight size marker MW-SBH. The basic relationship between migration distance and molecular weight was transformed using an exponential function. Fragment size frequency data show 2 peaks for pL159-1 at 4.36kb (2.36%) and 4.67 kb (6.29%) and one peak for pL355-8 at 6.04 kb (5.73%). The rate of heterozygosity exceeded 70% for both probes.
Pfaff
K
K
Institut für Anthropologie und Humangenetik, Tübingen, Germany.
Luckenbach
C
C
Ritter
H
H
D000483:Alleles; D015342:DNA Probes; D005787:Gene Frequency; D006580:Genetic Carrier Screening; D005858:Germany; D006801:Humans; D008970:Molecular Weight; D009154:Mutation; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid
D015342:DNA Probes