Vigabatrin-induced psychosis--management problems.
A 22-year-old patient with partial seizures developed schizophreniform psychosis following the introduction of vigabatrin. She stopped her anticonvulsant medication as a consequence of her persecutory delusions. She subsequently suffered status epilepticus with severe brain damage. It is essential to outline a management plan for patients to detect and treat vigabatrin-induced psychosis.
Jawad
S
S
Department of Psychiatry, East Glamorgan General Hospital, Church Village, UK.
Clarke
E
E
Richens
A
A
D000328:Adult; D001925:Brain Damage, Chronic / Q000139:chemically induced; D002220:Carbamazepine / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D013375:Substance Withdrawal Syndrome / Q000523:psychology; D020888:Vigabatrin; D005680:gamma-Aminobutyric Acid / Q000009:adverse effects / Q000031:analogs & derivatives*
D002220:Carbamazepine; D005680:gamma-Aminobutyric Acid; D020888:Vigabatrin