[The clinical evaluation of the antidepressive activity of fluoxetine].
The authors studied therapeutic properties of fluoxetine in the treatment of 100 patients with endogenous depressions. The drug was introduced during 6 weeks in a daily dose 20 mg. On the basis of the analysis of its clinical action and adverse reactions, fluoxetine belonging to the class of antidepressants has been ascertained. A prevalence of thymoleptic and stimulating components in its action, equal by their degree of expressivity and a smaller degree of anxiolytic effect have been demonstrated. Differentiated indications to fluoxetine prescription, its predilection in the therapy of apatho-adynamic and melancholic depressions and the feasibility of its use in inpatient conditions are discussed.
Lopukhov
I G
IG
Andrusenko
M P
MP
Vladimirova
T V
TV
Platonova
T P
TP
Chakhava
V O
VO
D000293:Adolescent; D000328:Adult; D000368:Aged; D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology; D005260:Female; D005473:Fluoxetine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011581:Psychological Tests; D011599:Psychopathology; D012074:Remission Induction; D013607:Tablets; D013997:Time Factors
D013607:Tablets; D005473:Fluoxetine
Klinicheskaia otsenka antidepressivnoĭ aktivnosti fluoksetina.