title: Neurophysiological model of tinnitus: dependence of the minimal masking level on treatment outcome.
abstract: Validity of the neurophysiological model of tinnitus (Jastreboff, 1990), outlined in this paper, was tested on data from multicenter trial of tinnitus masking (Hazell et al., 1985). Minimal masking level, intensity match of tinnitus, and the threshold of hearing have been evaluated on a total of 382 patients before and after 6 months of treatment with maskers, hearing aids, or combination devices. The data has been divided into categories depending on treatment outcome and type of approach used. Results of analysis revealed that: i) the psychoacoustical description of tinnitus does not possess a predictive value for the outcome of the treatment; ii) minimal masking level changed significantly depending on the treatment outcome, decreasing on average by 5.3 dB in patients reporting improvement, and increasing by 4.9 dB in those whose tinnitus remained the same or worsened; iii) 73.9% of patients reporting improvement had their minimal masking level decreased as compared with 50.5% for patients not showing improvement, which is at the level of random change; iv) the type of device used has no significant impact on the treatment outcome and minimal masking level change; v) intensity match and threshold of hearing did not exhibit any significant changes which can be related to treatment outcome. These results are fully consistent with the neurophysiological interpretation of mechanisms involved in the phenomenon of tinnitus and its alleviation.
authors.affiliation: University of Maryland School of Medicine, Department of Surgery, Baltimore 21201.
authors.forename: P J
authors.initials: PJ
authors.lastname: Jastreboff
authors.forename: J W
authors.initials: JW
authors.lastname: Hazell
authors.forename: R L
authors.initials: RL
authors.lastname: Graham
mesh_terms: D000161:Acoustic Stimulation; D000704:Analysis of Variance; D001309:Auditory Threshold / Q000502:physiology*; D003198:Computer Simulation; D006185:Habituation, Psychophysiologic; D006310:Hearing Aids; D006801:Humans; D008959:Models, Neurological; D010470:Perceptual Masking; D011571:Psychoacoustics; D014012:Tinnitus / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy