Membranous glomerulonephritis associated with hepatitis C virus infection in an adolescent.
The clinical, laboratory and pathological findings are reported in an adolescent patient with hyper-IgM immunodeficiency syndrome (dysgammaglobulinemia) which was complicated by primary sclerosing cholangitis and membranous glomerulonephritis. Hepatitis C virus (HCV) RNA was detected in serum by the polymerase chain reaction. A possible etiological relationship between hepatitis C virus infection and membranous nephropathy is discussed.
Romas
E
E
Department of Clinical Immunology, St Vincent's Hospital, Fitzroy.
Power
D A
DA
Machet
D
D
Powell
H
H
d'Apice
A J
AJ
D000293:Adolescent; D004406:Dysgammaglobulinemia / Q000150:complications; D015433:Glomerulonephritis, Membranous / Q000276:immunology / Q000821:virology*; D016174:Hepacivirus / Q000302:isolation & purification; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000097:blood
D012367:RNA, Viral