title: Isolation of Borrelia burgdorferi from two patients in Michigan.
abstract: Borrelia burgdorferi was isolated from skin biopsy specimens of erythema chronicum migrans lesions on two individuals residing in Menominee County, Michigan, in 1992. To our knowledge, these are the first two cases of culture-confirmed Lyme disease in Michigan. In spite of prompt treatment and resolution of illness, antibodies to B. burgdorferi were detectable for at least 3 months in both patients. Both specimens were obtained at different rural medical practices, thus demonstrating that with adequate laboratory support it is feasible to confirm a diagnosis of acute Lyme disease by culture in rural health care settings.
authors.affiliation: Bureau of Infectious Disease Control, Michigan Department of Public Health, Lansing.
authors.forename: M G
authors.initials: MG
authors.lastname: Stobierski
authors.forename: W N
authors.initials: WN
authors.lastname: Hall
authors.forename: B
authors.initials: B
authors.lastname: Robinson-Dunn
authors.forename: H
authors.initials: H
authors.lastname: Stiefel
authors.forename: S
authors.initials: S
authors.lastname: Shiflett
authors.forename: V
authors.initials: V
authors.lastname: Carlson
mesh_terms: D000328:Adult; D015748:Borrelia burgdorferi Group / Q000302:isolation & purification*; D015787:Erythema Chronicum Migrans / Q000382:microbiology; D006801:Humans; D008297:Male; D008824:Michigan; D008875:Middle Aged; D012867:Skin / Q000382:microbiology