Post-tetanic count and single twitch height at the onset of reflex movement after administration of vecuronium under different types of anaesthesia.
We have studied post-tetanic count (PTC) and single twitch height at the onset of reflex movement to carinal stimulation after administration of vecuronium with five different types of anaesthesia. Seventy-five adult patients were allocated randomly to five groups of 15 patients each, to receive one of the following anaesthetics: neuroleptanaesthesia (fentanyl and droperidol) or 1 MAC of either halothane, isoflurane, enflurane or sevoflurane with 66% nitrous oxide in oxygen. During spontaneous recovery from vecuronium-induced neuromuscular block, the carina was stimulated with a suction catheter every 150 s. Single twitch heights at the onset of reflex movement were similar (2.0-2.7% of control values) between the five groups. In contrast, PTC at the onset of reflex movement to carinal stimulation differed (7.4-17.0) between groups.
Saitoh
Y
Y
Department of Anaesthesiology and Critical Care Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
Kaneda
K
K
Toyooka
H
H
Amaha
K
K
D000328:Adult; D000769:Anesthesia, Inhalation; D004329:Droperidol; D005260:Female; D005283:Fentanyl; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D009458:Neuroleptanalgesia; D012018:Reflex / Q000187:drug effects*; D014132:Trachea / Q000502:physiology*; D014673:Vecuronium Bromide / Q000494:pharmacology*
D014673:Vecuronium Bromide; D004329:Droperidol; D005283:Fentanyl