title: Sulphasalazine desensitisation in patients with arthritis.
abstract: Skin rash is a common side effect of sulphasalazine. Desensitisation, with a gradual introduction of the drug, may prevent rash. This study reports a 33% (3/9 patients) success rate of desensitisation in patients with arthritis. Desensitisation should only be attempted if sulphasalazine has been efficacious in treating the joint symptoms.
authors.affiliation: Department of Rheumatology, Mater Misericordiae Hospital, Dublin.
authors.forename: C
authors.initials: C
authors.lastname: McCarthy
authors.forename: R
authors.initials: R
authors.lastname: Coughlan
mesh_terms: D000328:Adult; D000368:Aged; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D015535:Arthritis, Psoriatic / Q000188:drug therapy*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D003888:Desensitization, Immunologic; D003875:Drug Eruptions / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012460:Sulfasalazine / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use
chemical_list: D012460:Sulfasalazine