[Endo-epsilon-(gamma-Glu)Lys-isopeptidolysis as a sign of highly-specific proteolysis].
Catalytic activity of destabilase has been studied in hydrolyses of synthetic and natural substrates. High specificity of the enzyme is shown in hydrolysis of endo-epsilon-(gamma-Glu)Lys isopeptide bonds.
Baskova
I P
IP
Zavalova
L L
LL
Kuzina
E V
EV
D000595:Amino Acid Sequence; D000818:Animals; D002384:Catalysis; D010450:Endopeptidases / Q000378:metabolism*; D005343:Fibrinolytic Agents / Q000378:metabolism*; D005971:Glutamates / Q000378:metabolism*; D018698:Glutamic Acid; D006801:Humans; D006868:Hydrolysis; D008239:Lysine / Q000378:metabolism*; D008969:Molecular Sequence Data; D013379:Substrate Specificity
D005343:Fibrinolytic Agents; D005971:Glutamates; D018698:Glutamic Acid; D010450:Endopeptidases; C045348:fibrin destabilase; D008239:Lysine
Endo-epsilon-(gamma-Glu)Lys-izopeptidoliz kak proiavlenie vysokospetsificheskogo proteoliza.