[Sneddon's syndrome vasculopathy with antiphospholipid antibodies in a child].
We studied a ten-year old girl with livedo reticularis and multiple central nervous system ischemic attacks beginning when she was five. Blood tests were positive for cryoglobulins and antiphospholipid antibodies; superior limb angiography showed occlusion and irregularities of the vessel walls and temporal artery biopsy revealed concentric thickening of the vessel wall due to fibrotic subendothelial proliferation. Sneddon's syndrome was diagnosed. Onset of this syndrome during early childhood has not been previously reported.
Villaizán
C
C
Departamento de Pediatría, Facultad de Medicina, Universidad de Navarra, Pamplona.
Ferrada
M J
MJ
Legarda
I
I
Iriarte
J
J
Narbona
J
J
Martínez-Lage
J M
JM
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D017152:Antibodies, Antiphospholipid / Q000097:blood*; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D002675:Child, Preschool; D003342:Corpus Striatum / Q000503:physiopathology; D005260:Female; D005347:Fibroblasts / Q000648:ultrastructure; D006801:Humans; D008279:Magnetic Resonance Imaging; D017445:Skin Diseases, Vascular / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D017152:Antibodies, Antiphospholipid
Vasculopatía asociada a anticuerpos antifosfolípido. Síndrome de Sneddon en la niñez.