title: Chinese population data on the PCR-based loci HLA-DQ alpha, low-density-lipoprotein receptor, glycophorin A, hemoglobin gamma G, D7S8, and group-specific component.
abstract: Allele and genotype frequencies for six polymerase chain reaction (PCR)-based DNA genetic markers were determined in a Chinese sample population. The loci are HLA-DQ alpha, low-density-lipoprotein receptor, glycophorin A, hemoglobin gamma G, D7S8, and group-specific component. These results were obtained using the AmpliType HLA-DQ alpha forensic DNA amplification and typing kit and the AmpliType PM PCR amplification and typing kit. All loci met Hardy-Weinberg expectations and there was no evidence for association of alleles between the loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in the Chinese population.
authors.affiliation: Criminal Investigation Bureau, DNA Laboratory, Taipei, Taiwan, Republic of China.
authors.forename: N E
authors.initials: NE
authors.lastname: Huang
authors.forename: B
authors.initials: B
authors.lastname: Budowle
mesh_terms: D000483:Alleles; D002681:China; D005787:Gene Frequency; D005838:Genotype; D005914:Globins / Q000235:genetics*; D006021:Glycophorins / Q000235:genetics*; D006683:HLA-DQ Antigens / Q000235:genetics*; D059848:HLA-DQ alpha-Chains; D006801:Humans; D016133:Polymerase Chain Reaction; D011973:Receptors, LDL / Q000235:genetics*; D014809:Vitamin D-Binding Protein / Q000235:genetics*
chemical_list: D006021:Glycophorins; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; C069050:HLA-DQA1 antigen; D011973:Receptors, LDL; D014809:Vitamin D-Binding Protein; D005914:Globins