title: Cell functions in Drosophila oogenesis.
abstract: We are studying Drosophila oogenesis by analysing at genetic and molecular levels several female-sterile mutations. Some (hold up, wavoid-like and abnormal oocyte) have been isolated by L. Sandler in region 32 of the second chromosome; others have been isolated by us and their phenotype is presented for the first time in this paper. We performed chromosome walking in 32D-32E-F(250 Kb) and 32A-B(100 Kb) and in the last years we molecularly identified several genes with specific maternal expression patterns. We will review here our studies on two of these genes: the Vitelline Membrane Protein gene 32E and the gene coding for a receptor form of Guanylate Cyclase.
authors.affiliation: Istituto Internazionale di Genetica e Biofisica, Napoli, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Malva
authors.forename: F
authors.initials: F
authors.lastname: Graziani
authors.forename: G
authors.initials: G
authors.lastname: Gargiulo
authors.forename: A
authors.initials: A
authors.lastname: Manzi
mesh_terms: D000818:Animals; D004330:Drosophila / Q000502:physiology*; D004527:Egg Proteins / Q000235:genetics; D005260:Female; D017344:Genes, Insect / Q000235:genetics; D006162:Guanylate Cyclase; D009154:Mutation / Q000502:physiology; D009866:Oogenesis / Q000235:genetics*; D011956:Receptors, Cell Surface / Q000235:genetics
chemical_list: D004527:Egg Proteins; D011956:Receptors, Cell Surface; C035651:vitelline membrane proteins; D006162:Guanylate Cyclase