title: A new experimental model: for further investigation of the secondary changes following spinal cord injury.
abstract: To investigate the pathophysiology of spinal trauma, several experimental models have been used. In this study, the authors present a new experimental model for further investigation of secondary damage following spinal injury. Nd:YAG laser irradiation was applied to the spinal cord of guinea pigs to produce an injury. A 30 Watt (20 Joule) laser produced paraparesis. The injury was evaluated with evoked potentials, lipid peroxidation values, and histopathological examination.
authors.affiliation: Department of Neurosurgery, Hacettepe University, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Colak
authors.forename: G
authors.initials: G
authors.lastname: Nurlu
authors.forename: B
authors.initials: B
authors.lastname: Açikgöz
authors.forename: O E
authors.initials: OE
authors.lastname: Ozcan
authors.forename: E
authors.initials: E
authors.lastname: Aydim
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005073:Evoked Potentials, Somatosensory; D006168:Guinea Pigs; D007834:Lasers / Q000009:adverse effects; D015227:Lipid Peroxidation; D010264:Paraplegia / Q000209:etiology* / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D011833:Radiation Injuries, Experimental / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D011930:Reaction Time; D013119:Spinal Cord Injuries / Q000209:etiology / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology