title: Taurine regulation of Ca2+ uptake and (Ca(2+)+Mg2+)-ATPase in developing chick B-cells.
abstract: 1. The objective of the present study was to determine the effect of age and taurine on chick B cell calcium uptake and membrane (Ca(2+)+Mg2+)-ATPase activity in 1-4-week-old chicks. 2. The calcium uptake rate decreased with age (P < 0.05) and was further decreased by taurine (P < 0.05). 3. (Ca(2+)+Mg2+)-ATPase activity increased with age (P < 0.05) and was stimulated by taurine (P < 0.05). 4. The data demonstrate that the flux of calcium across the B-cell membrane changes during early post-hatch development, and that taurine regulates both the influx and efflux of calcium in chick B-cells.
authors.affiliation: Division of Animal and Veterinary Sciences, College of Agriculture and Forestry, West Virginia University, Morgantown 26506.
authors.forename: D W
authors.initials: DW
authors.lastname: Porter
authors.forename: W G
authors.initials: WG
authors.lastname: Martin
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000201:enzymology / Q000378:metabolism*; D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D002462:Cell Membrane / Q000201:enzymology; D002645:Chickens / Q000254:growth & development / Q000276:immunology* / Q000378:metabolism; D066298:In Vitro Techniques; D013654:Taurine / Q000502:physiology*
chemical_list: D013654:Taurine; D017301:Ca(2+) Mg(2+)-ATPase; D002118:Calcium