title: [VNTR-PCR in diagnosis of inherited Rb gene mutation].
abstract: Molecular genetic analysis of DNA by PCR-VNTR was performed in a family with hereditary retinoblastoma presenting some difficulties in pedigree analysis. PCR-VNTR allowed to perform a more accurate counselling in this family. Analysis of the way of transmission, carrier status exclusion (in two persons) and confirmation (in one) was possible only by VNTR-PCR.
authors.affiliation: Zakładu Genetyki i Patomorfologii, Szczecin.
authors.forename: S
authors.initials: S
authors.lastname: Zajaczek
authors.forename: B
authors.initials: B
authors.lastname: Górski
authors.forename: T
authors.initials: T
authors.lastname: Débniak
authors.forename: J
authors.initials: J
authors.lastname: Podolski
authors.forename: J
authors.initials: J
authors.lastname: Lubiński
authors.forename: Z
authors.initials: Z
authors.lastname: Krzystolik
authors.forename: T
authors.initials: T
authors.lastname: Iwanicka
authors.forename: Z
authors.initials: Z
authors.lastname: Sagan
mesh_terms: D000328:Adult; D001483:Base Sequence; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D016161:Genes, Retinoblastoma; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats; D008969:Molecular Sequence Data; D009154:Mutation; D010375:Pedigree; D016133:Polymerase Chain Reaction / Q000379:methods*; D012150:Polymorphism, Restriction Fragment Length; D012175:Retinoblastoma / Q000175:diagnosis / Q000235:genetics*
vernacular_title: VNTR-PCR w diagnostyce nosicielstwa zmutowanego genu Rb.