Intraoperative localization of recurrent medullary carcinoma of the thyroid using indium-111 pentetreotide and a nuclear surgical probe.
A patient with recurrent medullary thyroid cancer in the neck in whom previous surgery for recurrence had been undertaken with only partial success had the diseased tissue localized preoperatively by indium-111 pentetreotide. Scanning with technetium-99m V dimercaptosuccinic acid and iodine-123 metaiodobenzylguanidine failed to localize the tumor. Utilization of a nuclear surgical probe after preoperative 111In pentetreotide allowed accurate surgical localization of the tumour tissue.
Waddington
W A
WA
Institute of Nuclear Medicine, University College London Medical School, UK.
Kettle
A G
AG
Heddle
R M
RM
Coakley
A J
AJ
D000328:Adult; D018276:Carcinoma, Medullary / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D007205:Indium Radioisotopes; D007430:Intraoperative Care; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000601:surgery*; D011877:Radionuclide Imaging; D013004:Somatostatin / Q000031:analogs & derivatives*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*
D007205:Indium Radioisotopes; D013004:Somatostatin; C081788:pentetreotide