title: [Evaluation of selected immunologic parameters in healthy persons infected with mycobacterium tuberculosis bacillus].
abstract: Selected immunological parameters of peripheral blood leukocytes in 30 tb contracts and control group consisting of 30 healthy blood donors in similar age were examined. All contacts showed the exudate type Mantoux reaction (over 20 mm in diameter) and all revealed normal chest X-ray. No differences between both groups in total T cells, CD4, CD8 counts, CD4/CD8 ratio and in proliferative response to mitogens (PHA and Con A) were found. Tb contacts had the similar serum IgM and elevated IgG and IgA concentrations as compared with the controls. Tb contacts showed depressed granulocyte metabolic activity as measured by CL response to chemostatic peptide N-FORMYL-MET-LEU-PHE (FMLP) in comparison with control subjects.
authors.affiliation: Zakładu Immunologii Instytutu Gruźlicy i Chorób Płuc, Warszawie.
authors.forename: K
authors.initials: K
authors.lastname: Zabuska-Jabłońska
authors.forename: H
authors.initials: H
authors.lastname: Niemirowska-Mikulska
authors.forename: E
authors.initials: E
authors.lastname: Skopińska-Rózewska
authors.forename: I
authors.initials: I
authors.lastname: Sokolnicka
authors.forename: U
authors.initials: U
authors.lastname: Demkow
authors.forename: W
authors.initials: W
authors.lastname: Brajczewska-Fischer
authors.forename: R
authors.initials: R
authors.lastname: Lipińska
authors.forename: W
authors.initials: W
authors.lastname: Roszkowski
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006098:Granulocytes / Q000378:metabolism; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000097:blood; D008168:Lung / Q000000981:diagnostic imaging; D008213:Lymphocyte Activation; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D011859:Radiography; D014397:Tuberculosis, Pulmonary / Q000276:immunology*
chemical_list: D007136:Immunoglobulins
vernacular_title: Ocena wybranych czynności układu odpornościowego u zdrowych osób zakazonych pratkiem gruźlicy.