title: [The role of mutagenic factors in the development of diffuse toxic goiter].
abstract: The role of mutagenic factors in the onset of diffuse toxic goiter (DTG) was studied in 49 families of probands with DTG. The evidence obtained on the order in which the child was born in the proband's family, age of the parents at the time of DTG child delivery, implications of occupational factors in DTG onset does not rule out mutagenic effects in the origin of DTG and thus feasibility of the key gene influence on the disease predisposition.
authors.forename: A P
authors.initials: AP
authors.lastname: Kalinin
authors.forename: O P
authors.initials: OP
authors.lastname: Sidorova
authors.forename: T S
authors.initials: TS
authors.lastname: Kamynina
mesh_terms: D000293:Adolescent; D000328:Adult; D001327:Autoimmune Diseases / Q000209:etiology* / Q000235:genetics*; D001722:Birth Order; D002648:Child; D004198:Disease Susceptibility; D005260:Female; D006111:Graves Disease / Q000209:etiology* / Q000235:genetics*; D006801:Humans; D008297:Male; D008423:Maternal Age; D008875:Middle Aged; D016296:Mutagenesis; D010331:Paternal Age
vernacular_title: Rol' mutagennykh faktorov v razvitii diffuznogo toksicheskogo zoba.