title: [Neonatal hepatitis and biliary atresia].
abstract: The differential diagnosis between intrahepatic and extrahepatic cholestasis in the newborn is difficult and has therapeutic implications. 61 cases of neonatal cholestasis were retrospectively analyzed to assess the efficacy of various tests and procedures in differentiating between the 2 types. Determination of serum gamma-glutamyl transpeptidase, ultrasonography and radionuclide scanning differed significantly in the 2 types (p '0.05 for all 3 determinations). A diagnostic program for evaluation of infants with neonatal cholestasis is proposed.
authors.affiliation: Dept. of Pediatrics, Hadassah-University Hospital, Jerusalem.
authors.forename: O
authors.initials: O
authors.lastname: Portnoy
authors.forename: E
authors.initials: E
authors.lastname: Granot
authors.forename: S
authors.initials: S
authors.lastname: Katz
mesh_terms: D001656:Biliary Atresia / Q000175:diagnosis* / Q000000981:diagnostic imaging; D001651:Cholestasis, Extrahepatic / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D014463:Ultrasonography; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D005723:gamma-Glutamyltransferase