Cord blood banking for stem cell transplant.
Umbilical cord blood has been recently used as a source of hematopoietic progenitor cells for transplantation of pediatric patients. This study was performed to evaluate the feasibility of a cord blood bank for unrelated transplant. When the umbilical cord was clamped within 20 seconds after delivery, it was possible to collect 86 +/- 25 ml of cord recipients with more than 2000 CFU-GM/kg; 53% of cord blood samples were found to contain enough CFU-GM for engraftment in 50-70 kg adult patients.
Bertolini
F
F
Division of Hematology, Maggiore Hospital, Milano, Italy.
Lazzari
L
L
Corsini
C
C
Lauri
E
E
Gorini
F
F
Sirchia
G
G
D000328:Adult; D001771:Blood Banks; D003114:Colony-Forming Units Assay; D005312:Fetal Blood / Q000166:cytology*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans