title: Segi's cap: group formation of gut endocrine cells at the tip of the villi in human embryonal intestine.
abstract: Large groups of basal-granulated (entero-endocrine) cells occur on the top of villi in the duodenum and upper jejunum of the human fetus older than five months of gestation. This structure was discovered and described by Segi(1935), hence named Segi's cap. By the immunocytochemical technique, somatostatin-, gastrin- and motilin-producing cells were demonstrated. By electron microscopy, EC, D and S cells were identified in the cap. There were autonomic nerves in the lamina propria adjacent to Segi's cap. No intraepithelial lymphocytes were found in the villi with Segi's cap.
authors.affiliation: Department of Anatomy, Nagoya University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Iino
mesh_terms: D001078:APUD Cells / Q000648:ultrastructure*; D005314:Embryonic and Fetal Development / Q000502:physiology; D006801:Humans; D007422:Intestines / Q000196:embryology* / Q000648:ultrastructure; D008871:Microvilli / Q000648:ultrastructure