The polka dot liver and spleen: a case report.
Hepatomegaly occurring in association with an inhomogeneous liver documented on CT scanning in an individual with abnormal liver injury parameters is a common clinical finding. In most such cases, an increase in the canalicular enzymes (alkaline phosphatase and gamma-glutamyl transpeptidase) is present. Most individuals with this combination of findings are ill-appearing individuals with metastatic cancer. The same findings in an individual with few symptoms or one who appears quite fit is unusual and presents a unique problem in differential diagnosis. Herein we present such a case that, with appropriate medical therapy, had a near complete resolution of the biochemical and radiologic manifestations of disease.
Van Thiel
D H
DH
Oklahoma Transplantation Institute, Baptist Medical Center of Oklahoma, Oklahoma City 73112.
Hassanein
T
T
Gurakar
A
A
Caraceni
P
P
Nadir
A
A
Wright
H I
HI
D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006529:Hepatomegaly / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008099:Liver / Q000473:pathology*; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D013154:Spleen / Q000473:pathology*; D013163:Splenomegaly / Q000175:diagnosis* / Q000188:drug therapy
D011241:Prednisone