title: Urolithiasis related to laxative abuse.
abstract: Urinary calcareous disease related to laxative abuse is rare. The gastrointestinal loss of fluid and electrolytes leads to chronic depletion of the urinary volume, relative supersaturation and many other pathophysiologic derangements. These calculi are generally radiolucent with uric acid and ammonium acid urate as major components. We report on a female patient with frequent, repetitive formation of urinary calculi and rapid double J stent encrustation, which were related to the chronic abuse of bisacodyl. Although these stones can be fragmented successfully by extracorporeal shockwave lithotripsy, it seems that the better treatment for this type of stone formation is to avoid the abuse of laxatives.
authors.affiliation: Department of Urology, Kaohsiung Medical College, Taiwan, R.O.C.
authors.forename: W J
authors.initials: WJ
authors.lastname: Wu
authors.forename: C H
authors.initials: CH
authors.lastname: Huang
authors.forename: C P
authors.initials: CP
authors.lastname: Chiang
authors.forename: C N
authors.initials: CN
authors.lastname: Huang
authors.forename: C N
authors.initials: CN
authors.lastname: Wang
mesh_terms: D000328:Adult; D001726:Bisacodyl; D005260:Female; D006801:Humans; D019966:Substance-Related Disorders / Q000150:complications*; D014545:Urinary Calculi / Q000139:chemically induced*
chemical_list: D001726:Bisacodyl