Hepatitis C infection, cryoglobulinemia, and vasculitic neuropathy. Treatment with interferon alfa: case report and literature review.
A patient with mononeuropathy multiplex, hepatitis C viral infection, and mixed cryoglobulinemia had axonal degeneration by EMG and vasculitis of the epineurial vessels on sural nerve biopsy. There was no evidence of viral particles in the nerve by immunofluorescence. Treatment with interferon alfa improved the patient's symptoms and cleared the hepatitis C viral RNA and cryoglobulins from the serum.
Khella
S L
SL
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia.
Frost
S
S
Hermann
G A
GA
Leventhal
L
L
Whyatt
S
S
Sajid
M A
MA
Scherer
S S
SS
D000328:Adult; D003449:Cryoglobulinemia / Q000150:complications* / Q000503:physiopathology / Q000628:therapy / Q000821:virology; D004576:Electromyography; D006526:Hepatitis C / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D011930:Reaction Time / Q000502:physiology; D013497:Sural Nerve / Q000473:pathology / Q000503:physiopathology; D014657:Vasculitis / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy