title: Prevalence of obesity in young adults with acute lymphoblastic leukemia.
abstract: We studied the hormonal pattern of nine patients with acute lymphoblastic leukemia. The patients were treated with standard therapeutic regimens. They were overweight by a mean of 52% at the end of the consolidation treatment, and this persisted after a follow-up of 2 years. The only endocrine alteration observed was a moderate decrease in serum testosterone levels in male patients. The other parameters studied were in the normal range. We conclude that prolonged treatment with high doses of corticosteroids, which have a depressive effect on metabolism, was responsible for the obesity.
authors.affiliation: Istituto di Semeiotica Medica, Università Cattolica S. Cuore, Rome, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Pagano
authors.forename: G
authors.initials: G
authors.lastname: De Rosa
authors.forename: M T
authors.initials: MT
authors.lastname: Voso
authors.forename: R
authors.initials: R
authors.lastname: Marra
authors.forename: A
authors.initials: A
authors.lastname: Testa
authors.forename: G
authors.initials: G
authors.lastname: Leone
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001835:Body Weight; D005260:Female; D006728:Hormones / Q000097:blood*; D006801:Humans; D008297:Male; D009765:Obesity / Q000097:blood / Q000209:etiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D012189:Retrospective Studies; D013739:Testosterone / Q000097:blood
chemical_list: D006728:Hormones; D013739:Testosterone