title: Characterization of a new alpha-thalassemia-1 mutation in a Spanish family.
abstract: A novel alpha-thalassemia-1 deletion of 14-15.4 kb that removes the alpha-2, alpha-1, theta-1 genes and pseudo-alpha-1 genes, has been detected in a father and 2 of his children from northern Spain.
authors.affiliation: Hematology Service, Hospital Universitario San Carlos, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Villegas
authors.forename: J
authors.initials: J
authors.lastname: Sanchez
authors.forename: P
authors.initials: P
authors.lastname: Ricard
authors.forename: F A
authors.initials: FA
authors.lastname: Gonzalez
authors.forename: E
authors.initials: E
authors.lastname: Del Potro
authors.forename: B
authors.initials: B
authors.lastname: Armada
authors.forename: D L
authors.initials: DL
authors.lastname: Carreno
authors.forename: D
authors.initials: D
authors.lastname: Espinos
mesh_terms: D000328:Adult; D015139:Blotting, Southern; D002648:Child; D002885:Chromosomes, Human, Pair 16; D005260:Female; D017353:Gene Deletion; D005787:Gene Frequency; D005914:Globins / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D008297:Male; D009154:Mutation; D012150:Polymorphism, Restriction Fragment Length; D015995:Prevalence; D011544:Pseudogenes; D013030:Spain / Q000453:epidemiology; D017085:alpha-Thalassemia / Q000453:epidemiology / Q000235:genetics*
chemical_list: D005914:Globins