title: Micellar electrokinetic capillary chromatography with in situ charged micelles: 3. Evaluation of alkylglucoside surfactants as anionic butylboronate complexes.
abstract: This article represents an extension to a new approach introduced very recently by our laboratory for the control of the surface charge density as well as the hydrophobic character of micellar phases used in micellar electrokinetic capillary chromatography (MECC). The approach is based on the complexation of polyolic surfactants, e.g., alkylglucosides, with butylboronate to form in situ branched, anionic surfactants. The butylboronate can also incorporate into the micelle via its alkyl tail and acts as a "class I" organic additive that mainly modifies the micelle by decreasing the critical micellar concentration, i.e., increasing the hydrophobic character of the micelle, while exhibiting little influence on the aqueous phase. The net result is an in situ charged micellar entity whose hydrophobic character is dynamically altered. The alkylglucoside-butylboronate micellar phases yielded high separation efficiencies and proved useful in the separation of charged and neutral herbicides as well as the chiral separations of medicarpins and precursors, and dansylated D and L-amino acids in the presence of native or modified cyclodextrin chiral selectors.
authors.affiliation: Department of Chemistry, Oklahoma State University, Stillwater 74078-0447.
authors.forename: J T
authors.initials: JT
authors.lastname: Smith
authors.forename: Z
authors.initials: Z
authors.lastname: el Rassi
mesh_terms: D000596:Amino Acids / Q000302:isolation & purification; D000838:Anions; D001578:Benzopyrans / Q000302:isolation & purification; D001897:Boronic Acids; D002845:Chromatography / Q000379:methods*; D004563:Electrochemistry; D004586:Electrophoresis / Q000379:methods*; D005960:Glucosides; D006540:Herbicides / Q000302:isolation & purification; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D008823:Micelles; D036343:Pterocarpans; D013501:Surface-Active Agents; D000094162:Phytoalexins
chemical_list: D000596:Amino Acids; D000838:Anions; D001578:Benzopyrans; D001897:Boronic Acids; D005960:Glucosides; D006540:Herbicides; D008823:Micelles; D036343:Pterocarpans; D013501:Surface-Active Agents; C047353:medicarpin; D000094162:Phytoalexins