title: [Cutaneous reactions to heparin: immunological and clinical aspects].
abstract: Skin reactions to heparin are rare, the most frequent manifestation being skin necrosis. Reactions occur either as an isolated manifestation or within a context of heparin-induced thrombopenia. Urticarious and eczematous reaction, either localized at injection sites or with a general distribution, have been recently reported. In all cases, it is mandatory to withdraw heparin therapy. Such accidents can be observed with all types of heparin (standard heparin and low-molecular weight heparin). Cross-reactions between two types of heparin are frequent. Skin tests can be used to guide heparintherapy.
authors.affiliation: Service de Médecine interne, Hôpital Rothschild, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Mathelier-Fusade
authors.forename: A
authors.initials: A
authors.lastname: Deschamps
authors.forename: N
authors.initials: N
authors.lastname: Abuaf
authors.forename: F
authors.initials: F
authors.lastname: Leynadier
mesh_terms: D003875:Drug Eruptions / Q000276:immunology* / Q000628:therapy; D006493:Heparin / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000628:therapy; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000628:therapy
chemical_list: D006493:Heparin
vernacular_title: Réactions cutanées à l'héparine: aspects immunologiques et cliniques.