Bovine histidine-rich glycoprotein is a substrate for bovine plasma factor XIIIa.
Histidine-rich glycoprotein was purified from bovine plasma and the identity of the protein confirmed through amino acid sequencing. Activated bovine factor XIIIa catalyzed the incorporation of 1 nmol of 1,4-[14C]putrescine into 1 nmol of bovine histidine-rich glycoprotein, showing that histidine-rich glycoprotein has the ability to participate in transglutaminase-catalyzed reactions in vivo.
Halkier
T
T
Department of Molecular Biology and Plant Physiology, University of Aarhus, Denmark.
Andersen
H
H
Vestergaard
A
A
Magnusson
S
S
D000595:Amino Acid Sequence; D000818:Animals; D001798:Blood Proteins / Q000302:isolation & purification / Q000378:metabolism*; D002250:Carbon Radioisotopes; D002417:Cattle; D006023:Glycoproteins / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D008969:Molecular Sequence Data; D011506:Proteins / Q000302:isolation & purification / Q000378:metabolism*; D011700:Putrescine / Q000378:metabolism; D013379:Substrate Specificity; D011503:Transglutaminases / Q000302:isolation & purification / Q000378:metabolism*; D000099053:Histidine-Rich Glycoprotein
D001798:Blood Proteins; D002250:Carbon Radioisotopes; D006023:Glycoproteins; D011506:Proteins; D000099053:Histidine-Rich Glycoprotein; D011503:Transglutaminases; D011700:Putrescine