title: [The problems of spotted breeds of rabbits. 4. Morpho- and histometric findings in the CNS and thyroid glands and the hormone content in blood at slaughter of hybrid rabbits, and estimation of the heterosis effect].
abstract: Morpho- und histometric investigations of brains, pituitary and thyroid glands as well as thyroid-related functional parameters in the blood of purebred and hybrid rabbits revealed a predisposition to hypothyreotic conditions in homozygous, megacolon-prone genotypes. In addition to this also a hypoganglionotic state in different gut wall localizations was confirmed; pituitary traits however did not indicate a primary contribution of this gland to the syndrome, though some alterations were found, which are interpreted as secondary sv. symptomatic. Gender influences varied hormonal characteristics and disease manifestations too: A dramatic fall in severely diseased does with respect to T3-concentration as well as a seemingly more inactive thyroid gland compared to bucks underline hormonal influences. As a consequence of these results it is concluded, that hybridisation within spotted rabbits does not amend the inclination to megacolon in animals homozygous for the K (En) gene, though it may influence its manifestation.
authors.affiliation: Institut für Tierzucht und Vererbungsforschung der Tierärztlichen Hochschule Hannover.
authors.forename: K
authors.initials: K
authors.lastname: Flemming
authors.forename: C
authors.initials: C
authors.lastname: Kühnel
authors.forename: D
authors.initials: D
authors.lastname: Wieberneit
authors.forename: W
authors.initials: W
authors.lastname: Wegner
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D003433:Crosses, Genetic; D005260:Female; D006627:Hirschsprung Disease / Q000235:genetics / Q000662:veterinary; D006823:Hybrid Vigor; D008297:Male; D010902:Pituitary Gland / Q000033:anatomy & histology / Q000502:physiology; D011817:Rabbits / Q000235:genetics; D013961:Thyroid Gland / Q000033:anatomy & histology* / Q000502:physiology; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D013963:Thyroid Hormones
vernacular_title: Zur Problematik der Scheckenzucht bei Kaninchen. 4. Mitteilung: Morpho- und histometrische Befunde am ZNS und der Schilddrüse sowie SH-Gehalte im Schlachtblut von Hybridkaninchen, Beurteilung des Heterosiseffektes.