[Radioprotectors of receptor action].
Based on analysis of own and literature data the separate class of radioprotectors, namely protectors of receptor action, has been distinguished. The main subclassed and representatives, common peculiarities and advantages (especially, low values of ED50 and high therapeutic indexes) of the protectors have been characterized. Possible participation of second messengers and alternative (non-receptor) hypothesis of hormone radioprotective effect are discussed.
Kulinskiĭ
V I
VI
D000322:Adrenergic Agonists / Q000528:radiation effects*; D000818:Animals; D017442:Histamine Agonists / Q000528:radiation effects*; D006801:Humans; D011836:Radiation Tolerance; D011950:Receptors, Cholinergic / Q000528:radiation effects*; D018047:Receptors, Purinergic P1 / Q000528:radiation effects*; D017366:Serotonin Receptor Agonists / Q000528:radiation effects*
D000322:Adrenergic Agonists; D017442:Histamine Agonists; D011950:Receptors, Cholinergic; D018047:Receptors, Purinergic P1; D017366:Serotonin Receptor Agonists
Radioprotektory retseptornogo deĭstviia.