title: Bacterial plant oncogenes: the rol genes' saga.
abstract: The rol genes are part of the T-DNA which is transferred by Agrobacterium rhizogenes in plant cells, causing neoplastic growth and differentiation. Each of these bacterial oncogenes deeply influences plant development and is finely regulated once transferred into the plant host. Both from the study of the effects and biochemical function of the rol genes and from the analysis of their regulation, important insight in plant development can be derived. Some of the most intriguing aspects of past, current and future research on this gene system are highlighted and discussed.
authors.affiliation: Dip. Genetica e Biologia Molecolare, Università di Roma La Sapienza, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Costantino
authors.forename: I
authors.initials: I
authors.lastname: Capone
authors.forename: M
authors.initials: M
authors.lastname: Cardarelli
authors.forename: A
authors.initials: A
authors.lastname: De Paolis
authors.forename: M L
authors.initials: ML
authors.lastname: Mauro
authors.forename: M
authors.initials: M
authors.lastname: Trovato
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics*; D005798:Genes, Bacterial / Q000502:physiology*; D009857:Oncogenes; D063245:Plant Development; D010941:Plant Tumors / Q000382:microbiology; D010944:Plants / Q000235:genetics / Q000382:microbiology; D012231:Rhizobium / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; C036483:T-DNA; C075969:rol protein, Bacteria