A 24-month follow-up study of unipolar subjects: a comparison between lithium and fluvoxamine.
The authors compared rates of new episodes in a sample of 64 unipolar subjects treated with fluvoxamine (n = 32) and lithium (n = 32) during a follow-up period of 24 months. Unipolar patients on lithium treatment had a worse outcome with a higher frequency of new recurrences compared with of new recurrences compared with patients on fluvoxamine during the course of preventive treatment.
Franchini
L
L
Dipartimento di Scienze Neuropsichiche, Università degli Studi di Milano, Italy.
Gasperini
M
M
Smeraldi
E
E
D000328:Adult; D000368:Aged; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D016666:Fluvoxamine / Q000008:administration & dosage* / Q000009:adverse effects; D005500:Follow-Up Studies; D006801:Humans; D016651:Lithium Carbonate / Q000008:administration & dosage* / Q000009:adverse effects; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D012008:Recurrence; D016896:Treatment Outcome
D016651:Lithium Carbonate; D016666:Fluvoxamine