Ethiopian traditional herbal drugs. Part III: Anti-fertility activity of 70 medicinal plants.
A total of 210 extracts/fractions from 70 traditionally used Ethiopian plants were subjected to uterotonic and anti-implantation bioassays. A total of 24% of the samples had uterotonic activity and 33% exhibited anti-implantation activity, while 13% had both uterotonic and anti-implantation activity. The percentage cumulative activity for aqueous, 95% ethanolic and n-butanolic extracts/fractions was 10%, 31% and 25%, respectively. The number of plants whose aqueous extracts, 95% ethanolic extracts and n-butanolic fractions had both uterotonic and anti-implantation activity were 2, 15 and 11, respectively. These findings tend to support traditional claims of antifertility activity for some of the herbs.
Desta
B
B
School of Pharmacy, Addis Ababa University, Ethiopia.
D000818:Animals; D003271:Contraceptive Agents, Female / Q000494:pharmacology*; D010064:Embryo Implantation; D005002:Ethiopia; D005260:Female; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal; D051381:Rats; D017207:Rats, Sprague-Dawley; D014599:Uterus / Q000187:drug effects*
D003271:Contraceptive Agents, Female; D010936:Plant Extracts