title: Experimental model of posterolateral spinal arthrodesis in sheep. Part 2. Application of the model: evaluation of vertebral fusion obtained with coral (Porites) or with a biphasic ceramic (Triosite).
abstract: OBJECTIVE
  The authors evaluated two bone substitutes in a posterolateral spinal arthrodesis (PSA) model in sheep: coral porites (99% calcium carbonate, Biocoral, Inoteb, France) and a biphasic ceramic (BCP) (65% hydroxyapatite and 35% B tricalcium phosphate, Triosite, Zimmer International).
  
  
  BACKGROUND
  Bone substitutes would be of great interest for PSA. Previous trials began with two kinds of biomaterials: natural coralline calcium carbonate, and phosphate calcium ceramic.
  
  
  METHODS
  A lumbar PSA was performed in 11 sheep (coral group) and in 9 sheep (BCP group). Sacrifice and biomechanical tests were performed after 1 year.
  
  
  RESULTS
  A large decrease of flexibility in all directions was obtained with both coral PSA and BCP PSA similarly to autologous graft. No nonfusion case was observed.
  
  
  CONCLUSIONS
  In conditions close to the human surgery, a PSA can be obtained using either coral porites or BCP as bone substitutes.
authors.affiliation: Institut de recherche sur les Maladies du Squelette, Berck sur Mer, France.
authors.forename: P
authors.initials: P
authors.lastname: Guigui
authors.forename: P Y
authors.initials: PY
authors.lastname: Plais
authors.forename: B
authors.initials: B
authors.lastname: Flautre
authors.forename: E
authors.initials: E
authors.lastname: Viguier
authors.forename: M C
authors.initials: MC
authors.lastname: Blary
authors.forename: D
authors.initials: D
authors.lastname: Chopin
authors.forename: F
authors.initials: F
authors.lastname: Lavaste
authors.forename: P
authors.initials: P
authors.lastname: Hardouin
mesh_terms: D000818:Animals; D001174:Arthrodesis / Q000379:methods*; D001696:Biomechanical Phenomena; D018786:Bone Substitutes; D002119:Calcium Carbonate; D002516:Ceramics; D008422:Materials Testing; D018583:Pliability; D012756:Sheep; D013123:Spinal Fusion / Q000379:methods*
chemical_list: D018786:Bone Substitutes; D002119:Calcium Carbonate