title: Total parenteral nutrition--associated liver dysfunction.
abstract: We have reviewed all available data related to the development of liver dysfunction in patients receiving total parenteral nutrition (TPN). It seems that TPN-related liver dysfunction is multifactorial. Among all factors involved, two are most significant in the development of liver dysfunction, i.e. underlying disease and illness severity. In most cases, liver dysfunction is both self-limiting and reversible after cessation of TPN.
authors.affiliation: Department of Surgical Oncology and Nutrition, Cancer Institute, University of Montpellier, France.
authors.forename: J D
authors.initials: JD
authors.lastname: Spiliotis
authors.forename: F
authors.initials: F
authors.lastname: Kalfarentzos
mesh_terms: D002780:Cholestasis, Intrahepatic / Q000209:etiology; D005768:Gastrointestinal Hormones / Q000502:physiology; D005973:Glutamine / Q000502:physiology; D006801:Humans; D007422:Intestines / Q000382:microbiology / Q000503:physiopathology; D008107:Liver Diseases / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*
chemical_list: D005768:Gastrointestinal Hormones; D005973:Glutamine