The role of dermabrasion and chemical peels in the treatment of patients with xeroderma pigmentosum.
We describe our experience with two patients with xeroderma pigmentosum who underwent periodic trichloroacetic acid chemical peels. One also received a full-face dermabrasion. The effect of chemical peeling was more transient than dermabrasion but was associated with less morbidity. Both chemical peeling and dermabrasion provided a prophylactic effect against the development of skin malignancies; the latter had a more pronounced effect.
Nelson
B R
BR
Department of Dermatology, University of Michigan, Ann Arbor.
Fader
D J
DJ
Gillard
M
M
Baker
S R
SR
Johnson
T M
TM
D000293:Adolescent; D002280:Basal Cell Carcinoma / Q000517:prevention & control; D002294:Carcinoma, Squamous Cell / Q000517:prevention & control; D002615:Chemexfoliation / Q000009:adverse effects; D002648:Child; D003869:Dermabrasion / Q000009:adverse effects; D005153:Facial Neoplasms / Q000517:prevention & control / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D012878:Skin Neoplasms / Q000517:prevention & control / Q000601:surgery*; D014238:Trichloroacetic Acid / Q000627:therapeutic use*; D014983:Xeroderma Pigmentosum / Q000601:surgery*
D014238:Trichloroacetic Acid