Immunopharmacological studies of beta-1,3-glucan.
The influence of a nonsoluble beta-1,3-glucan preparation on the immune response of mice and rats to sheep red blood cells and to phytohemagglutinin A (PHA) T cell mitogen were evaluated. Treatment with glucan increased the hemagglutinin titers in both species and the response of mice spleen cells to PHA.
Ríos-Hernández
M
M
National Institute of Oncology and Radiobiology, Havana, Cuba.
Dos-Santos
N J
NJ
Silvia-Cardoso
Bello-Gárciga
J L
JL
Pedroso
M
M
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D005260:Female; D005936:Glucans / Q000494:pharmacology*; D006388:Hemagglutinins / Q000097:blood; D007155:Immunologic Factors / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D010835:Phytohemagglutinins / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley; D047071:beta-Glucans
D000276:Adjuvants, Immunologic; D005936:Glucans; D006388:Hemagglutinins; D007155:Immunologic Factors; D010835:Phytohemagglutinins; D047071:beta-Glucans; C033363:beta-1,3-glucan