Small nuclear RNAs and pre-mRNA splicing.
Genetic and biochemical studies have recently shown that the splice sites in nuclear pre-mRNAs are aligned for the transesterification reactions through a collaboration between U5 and U6 small nuclear RNAs, which form the heart of a network of RNA-based interactions in the active spliceosome.
Newman
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MRC Laboratory of Molecular Biology, Cambridge, UK.
D000818:Animals; D001483:Base Sequence; D006801:Humans; D008969:Molecular Sequence Data; D012326:RNA Splicing; D012333:RNA, Messenger / Q000235:genetics*; D012342:RNA, Small Nuclear / Q000235:genetics*; D013997:Time Factors
D012333:RNA, Messenger; D012342:RNA, Small Nuclear