title: A case of secondary syphilis with mucous patches on the hard palate.
abstract: A rare case of secondary syphilis showing mucous patches on the hard palate is reported. A 31-year-old male had two erosive patches which were slightly raised on his hard palate. A linear lesion was also present on the inside of his right alveolar process. Many red-brown macules on his abdomen and bilateral inguinal lymphadenopathy accompanied these symptoms. The serological tests for syphilis were positive: VDRL test 1:512, TPHA test 1:20,480, and IgM-FTA-ABS test 1:40. Immunohistochemical staining with rabbit monoclonal antibody to Treponema pallidum by the biotin-streptoavidin system detected treponemal organisms in the paraffin-embedded specimen from his mucous patch. A diagnosis of secondary syphilis was made, and he was given amoxicillin (AMPC) at 750 mg per day for 4 weeks. His eruptions, including the mucous patch, healed in a week.
authors.affiliation: Division of Dermatology, Hashima City Hospital, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ban
authors.forename: M
authors.initials: M
authors.lastname: Ohtani
authors.forename: M
authors.initials: M
authors.lastname: Seishima
mesh_terms: D000328:Adult; D000539:Alveolar Process / Q000473:pathology; D000658:Amoxicillin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology*; D010159:Palate / Q000473:pathology*; D013587:Syphilis / Q000188:drug therapy / Q000473:pathology*; D013588:Syphilis Serodiagnosis; D013591:Syphilis, Cutaneous / Q000188:drug therapy / Q000473:pathology
chemical_list: D000658:Amoxicillin