title: Response to Taxol chemotherapy in resistant ovarian carcinoma.
abstract: Taxol was administered to 25 patients with progressive ovarian cancer who had failed three or more lines of chemotherapy. A response rate of 27% was noted in 22 evaluable patients (5 partial responders; 1 complete responder). Median duration of response was only eight weeks. The impact of Taxol's use in this disease awaits the result of trials in which it is administered as first line therapy.
authors.affiliation: Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, New York.
authors.forename: T R
authors.initials: TR
authors.lastname: Baker
authors.forename: M S
authors.initials: MS
authors.lastname: Piver
authors.forename: R E
authors.initials: RE
authors.lastname: Hempling
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D017239:Paclitaxel / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D017239:Paclitaxel