title: [Disorders in the plasma and cellular hemostatic components of patients with HIV infection].
abstract: Plasmic and platelet components of hemostasis were investigated in 100 HIV-infected subjects. Its degree depended on the infection stage and associated opportunistic infections. The key factor in pathogenesis of hemocoagulatory disorders is reduced count, abnormal function and morphology of platelets. A direct relationship exists between the number of CD4-lymphocytes, a decline in the number and functional activity of platelets. Intravenous injection of immunoglobulin made in Russia as an adjuvant to combined therapy of HIV-infected subjects contributes to recovery of platelet count and aggregation.
authors.forename: A M
authors.initials: AM
authors.lastname: Poliakova
authors.forename: A V
authors.initials: AV
authors.lastname: Kravchenko
authors.forename: O S
authors.initials: OS
authors.lastname: Astrina
authors.forename: L V
authors.initials: LV
authors.lastname: Serebrovskaia
authors.forename: O G
authors.initials: OG
authors.lastname: Iurin
authors.forename: V V
authors.initials: VV
authors.lastname: Pokrovskiĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Maleev
mesh_terms: D000936:Antigen-Antibody Complex / Q000097:blood; D001778:Blood Coagulation Disorders / Q000097:blood* / Q000276:immunology; D001792:Blood Platelets / Q000276:immunology; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000276:immunology; D015497:HIV-1; D006487:Hemostasis; D006801:Humans; D007111:Immunity, Cellular; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D010949:Plasma / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G
vernacular_title: Narusheniia v plazmennom i kletochnom zvene gemostaza bol'nykh s VICh-infektsieĭ.