Treatment dilemmas in HIV infection.
Recent trials of early treatment with the nucleoside analogues have produced conflicting data, raising fundamental questions about this therapy. Nevertheless, these drugs do lengthen clinical latency and delay the onset of AIDS, and for that reason alone should not be abandoned. The new treatment guidelines of the National Institute of Allergy and Infectious Diseases are discussed.
Volberding
P A
PA
University of California, School of Medicine, San Francisco.
D015496:CD4-Positive T-Lymphocytes; D002986:Clinical Trials as Topic; D015224:Dideoxynucleosides / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007958:Leukocyte Count; D009316:National Institutes of Health (U.S.); D017410:Practice Guidelines as Topic; D014481:United States
D015224:Dideoxynucleosides