title: The polka dot liver and spleen: a case report.
abstract: Hepatomegaly occurring in association with an inhomogeneous liver documented on CT scanning in an individual with abnormal liver injury parameters is a common clinical finding. In most such cases, an increase in the canalicular enzymes (alkaline phosphatase and gamma-glutamyl transpeptidase) is present. Most individuals with this combination of findings are ill-appearing individuals with metastatic cancer. The same findings in an individual with few symptoms or one who appears quite fit is unusual and presents a unique problem in differential diagnosis. Herein we present such a case that, with appropriate medical therapy, had a near complete resolution of the biochemical and radiologic manifestations of disease.
authors.affiliation: Oklahoma Transplantation Institute, Baptist Medical Center of Oklahoma, Oklahoma City 73112.
authors.forename: D H
authors.initials: DH
authors.lastname: Van Thiel
authors.forename: T
authors.initials: T
authors.lastname: Hassanein
authors.forename: A
authors.initials: A
authors.lastname: Gurakar
authors.forename: P
authors.initials: P
authors.lastname: Caraceni
authors.forename: A
authors.initials: A
authors.lastname: Nadir
authors.forename: H I
authors.initials: HI
authors.lastname: Wright
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006529:Hepatomegaly / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008099:Liver / Q000473:pathology*; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D013154:Spleen / Q000473:pathology*; D013163:Splenomegaly / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D011241:Prednisone