Blink reflex in Wilson's disease.
Blink reflex and brainstem auditory evoked potential (BAEP) were studied in 10 patients with Wilson's disease (WD) and 10 family members. In blink reflex, R1 and R2 latencies as well as R2 duration were prolonged in the patient group, but not in the family group. In BAEP, latencies of peaks III and V and interpeaks I-III, III-V and I-V were also delayed only in the patient group. These data suggest that blink reflex abnormalities in WD are different from other movement disorders and are mainly due to brainstem dysfunction.
Chu
N S
NS
Department of Neurology, Chang Gung Medical College and Memorial Hospital, Taipei, Taiwan, R.O.C.
D000293:Adolescent; D000328:Adult; D001767:Blinking; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006527:Hepatolenticular Degeneration / Q000503:physiopathology*; D006801:Humans; D008297:Male; D011930:Reaction Time