Collagenous colitis: a cause of chronic diarrhea.
Collagenous colitis should be added to the differential diagnosis of chronic, watery, nonbloody diarrhea with normal endoscopic findings. Patients with collagenous colitis are often middle-aged women previously diagnosed as having irritable bowel syndrome. The diagnosis of collagenous colitis is based on histologic evaluation of a rectal biopsy specimen. Biopsy shows a thickened, subepithelial, acellular, eosinophilic collagen band. Symptoms often resolve after treatment with oral sulfasalazine.
Brady
S K
SK
University of Nevada School of Medicine, Reno.
McKee
D D
DD
D000367:Age Factors; D001466:Barium Sulfate; D001706:Biopsy; D002908:Chronic Disease; D003092:Colitis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000473:pathology; D003095:Collagen Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology*; D004733:Enema; D005260:Female; D006801:Humans; D008875:Middle Aged; D012737:Sex Factors; D012812:Sigmoidoscopy; D012460:Sulfasalazine / Q000008:administration & dosage / Q000627:therapeutic use
D001466:Barium Sulfate; D012460:Sulfasalazine