title: Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis.
abstract: Conjugative transposon Tn916 from Enterococcus faecalis DS16 encodes tetracycline resistance (Tet M) as well as determinants necessary for its own movement. Determination of the nucleotide sequence of Tn916 has been completed. The element is 18,032 bp in length and has an overall G+C content of 38.8%. Twenty-four potential open reading frames (ORFs) were identified based on sequence analysis. Similarities of the ORFs to other known determinants, which were revealed by database searches, are discussed.
authors.affiliation: Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor 48109-0402.
authors.forename: S E
authors.initials: SE
authors.lastname: Flannagan
authors.forename: L A
authors.initials: LA
authors.lastname: Zitzow
authors.forename: Y A
authors.initials: YA
authors.lastname: Su
authors.forename: D B
authors.initials: DB
authors.lastname: Clewell
mesh_terms: D001483:Base Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D003227:Conjugation, Genetic; D004251:DNA Transposable Elements; D004269:DNA, Bacterial / Q000235:genetics; D013293:Enterococcus faecalis / Q000187:drug effects / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics; D016366:Open Reading Frames; D013753:Tetracycline Resistance / Q000235:genetics
chemical_list: D004251:DNA Transposable Elements; D004269:DNA, Bacterial