[Cutaneous reactions to heparin: immunological and clinical aspects].
Skin reactions to heparin are rare, the most frequent manifestation being skin necrosis. Reactions occur either as an isolated manifestation or within a context of heparin-induced thrombopenia. Urticarious and eczematous reaction, either localized at injection sites or with a general distribution, have been recently reported. In all cases, it is mandatory to withdraw heparin therapy. Such accidents can be observed with all types of heparin (standard heparin and low-molecular weight heparin). Cross-reactions between two types of heparin are frequent. Skin tests can be used to guide heparintherapy.
Mathelier-Fusade
P
P
Service de Médecine interne, Hôpital Rothschild, Paris.
Deschamps
A
A
Abuaf
N
N
Leynadier
F
F
D003875:Drug Eruptions / Q000276:immunology* / Q000628:therapy; D006493:Heparin / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000628:therapy; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000628:therapy
D006493:Heparin
Réactions cutanées à l'héparine: aspects immunologiques et cliniques.