title: Nucleotide sequence of a full-length cDNA encoding a common precursor of platelet aggregation inhibitor and hemorrhagic protein from Calloselasma rhodostoma venom.
abstract: The nucleotide sequence of a full-length cDNA encoding the common precursor of a platelet aggregation inhibitor, rhodostomin and a hemorrhagic protein from Calloselasma rhodostoma snake venom is presented. The 1.98-kb cDNA contains an open reading frame encoding 478 amino acid residues. The complete structure of the precursor protein encoded by the cDNA is elucidated.
authors.affiliation: Department of Medical Research, Veterans General Hospital-Taipei, Taiwan, ROC.
authors.forename: L C
authors.initials: LC
authors.lastname: Au
authors.forename: J S
authors.initials: JS
authors.lastname: Chou
authors.forename: K J
authors.initials: KJ
authors.lastname: Chang
authors.forename: G W
authors.initials: GW
authors.lastname: Teh
authors.forename: S B
authors.initials: SB
authors.lastname: Lin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003435:Crotalid Venoms / Q000737:chemistry*; D008666:Metalloendopeptidases / Q000235:genetics*; D008969:Molecular Sequence Data; D010455:Peptides / Q000235:genetics*; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry*; D011498:Protein Precursors / Q000737:chemistry / Q000235:genetics*; D012911:Snakes
chemical_list: D003435:Crotalid Venoms; D010455:Peptides; D010975:Platelet Aggregation Inhibitors; D011498:Protein Precursors; C072026:rhodostomin; D008666:Metalloendopeptidases; C073275:hemorrhagic protease, Calloselasma rhodostoma