title: Influence of insulin on the movement of Tetrahymena pyriformis. Hormonal imprinting alters the velocity.
abstract: Treatment with insulin, cyclic adenosine monophosphate (cAMP) or theophylline, which uniformly influence the intracellular cAMP level, accounted for appreciable changes in the movement of Tetrahymena pyriformis. All applied treatments caused a quantitative decrease in the percentage of relatively rapid movements (straight and spiral swimming) and a proportional increase in that of slow movements (standing, turn, creeping). A single treatment with insulin caused a quantitative decrease in fast movements and a quantitative increase in slow movements also in the offspring generations and reexposure to insulin had a similar, but even stronger effect.
authors.affiliation: Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
authors.forename: P
authors.initials: P
authors.lastname: Kovács
authors.forename: G
authors.initials: G
authors.lastname: Lovas
authors.forename: G
authors.initials: G
authors.lastname: Csaba
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000187:drug effects; D000242:Cyclic AMP / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology*; D013769:Tetrahymena pyriformis / Q000166:cytology / Q000187:drug effects*; D013806:Theophylline / Q000494:pharmacology
chemical_list: D007328:Insulin; D013806:Theophylline; D000242:Cyclic AMP