title: [Anthelmintic resistance in sheep nematodes in The Netherlands].
abstract: The prevalence of anthelmintic resistant nematodes in sheep was investigated in 1994 with a faecal egg count reduction test (FECRT) and an egg hatch assay (EHA) on 71 farms in the Netherlands. A benzimidazole (oxfendazole) was tested on 70 farms, ivermectin on 51 farms, and levamisole on 35 farms. Based on the FECRT benzimidazole resistance was present on 56 farms, 2 were suspected, on 9 no resistance was observed, while 3 farms could not be tested due to a too low egg output before treatment. No clear indications for resistance to ivermectin and levamisole were found. Benzimidazole resistance was demonstrated in Haemonchus contortus, Cooperia curticei, Ostertagia spp. and/or Trichostrongylus spp. No resistance was seen in species from the genus Nematodirus, Chabertia ovina and/or Oesophagostomum spp. De results of the EHA confirmed the results of the FECRT. On 59 farms the ED50 value was > 0.12 microgram ml-1 thiabendazole.
authors.affiliation: DLO-Instituut voor Veehouderij en Diergezondheid (ID-DLO), Lelystad.
authors.forename: F H
authors.initials: FH
authors.lastname: Borgsteede
authors.forename: J J
authors.initials: JJ
authors.lastname: Pekelder
authors.forename: D P
authors.initials: DP
authors.lastname: Dercksen
authors.forename: J
authors.initials: J
authors.lastname: Sol
authors.forename: P
authors.initials: P
authors.lastname: Vellema
authors.forename: C P
authors.initials: CP
authors.lastname: Gaasenbeek
authors.forename: J N
authors.initials: JN
authors.lastname: van der Linden
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D001562:Benzimidazoles / Q000494:pharmacology; D004351:Drug Resistance; D007559:Ivermectin / Q000494:pharmacology; D009348:Nematoda / Q000187:drug effects*; D010270:Parasite Egg Count / Q000662:veterinary; D012756:Sheep / Q000469:parasitology*
chemical_list: D000871:Anthelmintics; D001562:Benzimidazoles; D007559:Ivermectin
vernacular_title: Anthelmintica-resistentie bij nematoden van het schaap in Nederland.