title: Partial homograft replacement of mitral valve.
abstract: To date, treatment of mitral valve disease with mitral homograft implantation has been unsatisfactory. We describe two cases of mitral valve repair in man with a cryopreserved partial mitral homograft. Massive mitral insufficiency was surgically corrected by replacement of the severely affected posterior leaflet and the subvalvular apparatus with their corresponding mitral-valve homograft tissue. 22 and 4 months after surgery, the repaired valves remain competent with flexible and normal functioning leaflets and subvalvular apparatus, and the patients are symptom-free.
authors.affiliation: Hospital Universitario Valdecilla, Universidad de Cantabria, Santander, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Revuelta
authors.forename: J M
authors.initials: JM
authors.lastname: Bernal
authors.forename: J M
authors.initials: JM
authors.lastname: Rabasa
mesh_terms: D000368:Aged; D015925:Cryopreservation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000637:transplantation*; D008944:Mitral Valve Insufficiency / Q000601:surgery; D014184:Transplantation, Homologous