Serum IgE levels in human immunodeficiency virus (HIV)-1 infected patients: correlation between IgE and CD4+ cells.
Human immunodeficiency virus (HIV) infection is associated, like allergic diseases, with altered T cell regulation. Total serum IgE levels were measured in 65 infected patients. The mean IgE level of subjects with a T lymphocytes number < or = 200/mmc was greater than mean IgE level of subjects with a T cell number > 200/mmc. No prevalence of atopic diseases was noted in the two groups. The elevation of IgE may be related to a difference in IgE regulatory lymphokines produced by T lymphocytes.
Ferrazzi
M
M
Institute of Infectious Diseases, University La Sapienza, Rome, Italy.
De Rinaldis
M L
ML
Salotti
A
A
Cirelli
A
A
D000328:Adult; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D005260:Female; D015658:HIV Infections / Q000276:immunology*; D015497:HIV-1; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged
D007073:Immunoglobulin E