[The efficacy of ticlid in treating intermittent claudication in atherosclerotic stenosis of the arteries of the lower extremities].
Serious affections of hemostasis were found in hemostatic examinations involving 67 intermittent claudication patients resistant to longterm vasodilative drugs. A 4-6-month course of tiklid (500 mg daily) induced a significant fall in platelet aggregation and an increase in the blood fibrinolytic activity, decreased foot chilliness, pain while walking. 73% of the patients could cover longer distances without pain complaints.
Kirichenko
A A
AA
Prekina
V I
VI
Repinskaia
N P
NP
Novichkova
Iu N
IuN
Ter-Gevondian
N M
NM
Vinogradova
I V
IV
D000328:Adult; D001161:Arteriosclerosis / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D001780:Blood Coagulation Tests; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D007383:Intermittent Claudication / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D007866:Leg / Q000098:blood supply*; D007925:Leriche Syndrome / Q000097:blood / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged; D013988:Ticlopidine / Q000627:therapeutic use*
D013988:Ticlopidine
Effektivnost' tiklida pri lechenii peremezhaiushcheĭsia khromoty u bol'nykh s ateroskleroticheskim stenozirovaniem arteriĭ nizhnikh konechnosteĭ.