[The new Russian preparation proxodolol in the treatment of arterial hypertension].
The clinical and instrumental investigations of 38 patients with mild and moderate arterial hypertension have shown that therapy with proxodolol in a daily dose of 120 mg results in correction of blood pressure in 79% of the patients. Proxodolol lowers blood pressure and total peripheral vascular resistance, diminished heart rate and causes some changes in pump functional parameters for the worse. The efficacy and tolerance of proxolol are similar to those of trandate and albetol.
Ol'binskaia
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Morozova
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D000293:Adolescent; D000317:Adrenergic alpha-Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology; D007741:Labetalol / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010069:Oxadiazoles / Q000009:adverse effects / Q000627:therapeutic use*; D012189:Retrospective Studies; D013997:Time Factors
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D010069:Oxadiazoles; C088649:proxodolol; D007741:Labetalol
Novyĭ otechestvennyĭ preparat proksodolol v lechenii arterial'noĭ gipertenzii.