title: Psychiatric comorbidity, health status, and functional impairment associated with alcohol abuse and dependence in primary care patients: findings of the PRIME MD-1000 study.
abstract: The psychiatric comorbidity, health, and functioning of primary care patients with alcohol abuse and dependence (AAD) were investigated in a sample of 1,000 patients. Psychiatric symptomatology was assessed with the Primary Care Evaluation of Mental Disorders (PRIME-MD) diagnostic system. Health and functional status was assessed with the Medical Outcomes Study Short Form General Health Survey (SF-20). Results indicated that use of the PRIME-MD system brought about a 71% increase in physician recognition of AAD. AAD patients were diagnosed with substantial psychiatric comorbidity, and they reported poorer health and functioning than did patients without any psychiatric disorders. However, they reported less impairment and psychiatric comorbidity than did patients with other psychiatric disorders. Results also indicated that AAD patients' health and functioning were associated with the presence or absence of psychiatric comorbidity.
authors.affiliation: Department of Psychiatry, Columbia University, New York, New York.
authors.forename: J G
authors.initials: JG
authors.lastname: Johnson
authors.forename: R L
authors.initials: RL
authors.lastname: Spitzer
authors.forename: J B
authors.initials: JB
authors.lastname: Williams
authors.forename: K
authors.initials: K
authors.lastname: Kroenke
authors.forename: M
authors.initials: M
authors.lastname: Linzer
authors.forename: D
authors.initials: D
authors.lastname: Brody
authors.forename: F
authors.initials: F
authors.lastname: deGruy
authors.forename: S
authors.initials: S
authors.lastname: Hahn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D015995:Prevalence; D011320:Primary Health Care; D011569:Psychiatric Status Rating Scales; D019966:Substance-Related Disorders / Q000150:complications* / Q000175:diagnosis; D011795:Surveys and Questionnaires