[Evaluation of the effects of methods of suppurative-inflammatory complications prevention after cesarean section on cellular and humoral components of the immune system].
The immune status of 73 pregnant women and puerperae, administered proteolysis inhibitors or common antibacterial therapy to prevent pyoseptic complications, was assessed before cesarean section and 1 and 7 days after it. The results indicate certain shifts in the immunity status of puerperae of all groups, which were the most expressed 1 day after surgery (reduced content of CD3 lymphocytes, IgG and IgA, and a marked increase of the content of C-reactive protein) and normalized by day 7 postoperation. These changes are most likely to be caused by the surgical intervention but not the infectious inflammatory process, which is proved by the absence of pyoseptic complications after prophylactic measures taken. Hence, proteolysis inhibitors, along with the traditional methods, may be recommended for the prevention of pyoseptic complications after cesarean section.
Chernukha
E A
EA
Van'ko
L V
LV
Chilingirov
R Kh
RKh
Naumov
Iu G
IuG
Matveeva
N K
NK
Naumova
S M
SM
Sukhikh
G T
GT
D000328:Adult; D000917:Antibody Formation / Q000187:drug effects*; D002097:C-Reactive Protein / Q000032:analysis; D002585:Cesarean Section / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007249:Inflammation; D011247:Pregnancy; D011300:Preoperative Care; D011480:Protease Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D011644:Puerperal Disorders / Q000276:immunology / Q000517:prevention & control*; D011645:Puerperal Infection / Q000276:immunology / Q000517:prevention & control*; D013492:Suppuration; D016176:T-Lymphocyte Subsets
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011480:Protease Inhibitors; D002097:C-Reactive Protein
Otsenka vliianiia na kletochnyĭ i gumoral'nyĭ komponenty immunnoĭ sistemy zhenshchiny nekotorykh metodov profilaktiki gnoĭno-vospalitel'nykh oslozhneniĭ posle kesareva secheniia.