Tests for the antibacterial activity of surgical glove material.
In-vitro and in-vivo models for testing the antibacterial activity of glove materials are described. The models were tested using four types of material: latex containing residual accelerator, latex treated by solvent-extraction to remove accelerator, material from hypo-allergenic accelerator-free gloves, and latex coated with quaternary ammonium compounds. In-vitro tests revealed two distinct types of antibacterial activity, one related to the accelerator which was slow-acting, and not neutralizable, and a second faster-acting neutralizable activity due to the quaternary ammonium compounds. The antiseptic coated material also showed antibacterial activity on human skin.
Newsom
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Papworth Hospital, Cambridge, UK.
Shaw
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D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001548:Benzalkonium Compounds / Q000494:pharmacology; D003030:Coagulase; D005932:Gloves, Surgical; D006801:Humans; D007840:Latex; D012867:Skin / Q000382:microbiology*; D013210:Staphylococcus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D001548:Benzalkonium Compounds; D003030:Coagulase; D007840:Latex