[The efficacy of polyoxydine and mafusol in the combined treatment of acute surgical blood loss].
The authors have studied the efficiency of new blood substitutes (polyoxidin and mafusol) in complex infusion-transfusion therapy in operations on lungs. During surgical interventions these medications were administered in doses of 717.0 +/- 30.0 ml and 914.0 +/- 74.0 correspondingly, and one day after the operation--400 ml each. Operational blood losses were 1.25 +/- 0.9 l. It was found out that polyoxidin and mafusol have executed positive influence upon various factors of pathophysiological mechanisms, and thus were effective in complex treatment of blood losses or shock states.
Artemov
V G
VG
Butko
G V
GV
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000208:Acute Disease; D016063:Blood Loss, Surgical / Q000503:physiopathology; D001802:Blood Substitutes / Q000494:pharmacology / Q000627:therapeutic use*; D004341:Drug Evaluation; D005561:Formates / Q000494:pharmacology / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects; D006490:Hemostatics / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008168:Lung / Q000601:surgery; D011092:Polyethylene Glycols
D001802:Blood Substitutes; D005561:Formates; D006490:Hemostatics; C081207:polyoxydine; C030544:formic acid; D011092:Polyethylene Glycols
Effektivnost' polioksidina i mafusola v kompleksnom lechenii ostroĭ operatsionnoĭ krovopoteri.