title: High-output heart failure as a cause of pulmonary hypertension.
abstract: Two cases of high-output heart failure associated with pulmonary hypertension are presented. In a 32-year-old man with hyperthyroidism, pulmonary hypertension subsided after antithyroid therapy. Increased pulmonary blood flow and elevated left ventricular end-diastolic pressure were suspected as the causes of pulmonary hypertension. In a 51-year-old man with cardiac beriberi, the pulmonary hypertension improved after thiamine administration. We suspect that increased pulmonary blood flow, elevated left ventricular end-diastolic pressure, and probably pulmonary vasoconstriction were the causes of pulmonary hypertension. Thus, high-output heart failure should be considered as a possible cause of pulmonary hypertension and right ventricular failure.
authors.affiliation: Department of Internal Medicine, Amagasaki Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Okura
authors.forename: Y
authors.initials: Y
authors.lastname: Takatsu
mesh_terms: D000328:Adult; D001602:Beriberi / Q000150:complications; D016534:Cardiac Output, High / Q000150:complications*; D004232:Diuretics / Q000627:therapeutic use; D004452:Echocardiography; D006111:Graves Disease / Q000150:complications; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D013831:Thiamine / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use; D018497:Ventricular Dysfunction, Right / Q000209:etiology
chemical_list: D004232:Diuretics; D014665:Vasodilator Agents; D013831:Thiamine