[Estimation of evolutionary distances between protein sequences].
Several estimates of the evolutionary distance between two homologous protein sequences were deduced, taking into account of the variation of replacement rate over amino acid sites. A maximum likelihood estimator was also presented with consideration of different probabilities of replacement among amino acids. Suggestions were made as to the application of these distance estimates to real sequence analysis.
Yang
Z
Z
Department of Animal Science, Beijing Agricultural University.
D000818:Animals; D005075:Biological Evolution; D002417:Cattle / Q000235:genetics; D004330:Drosophila / Q000235:genetics; D006736:Horses / Q000235:genetics; D006801:Humans; D011506:Proteins / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D015003:Yeasts / Q000235:genetics
D011506:Proteins