title: Clustered mutations in the transcriptional activation domain of Myc in 8q24 translocated lymphomas and their functional consequences.
authors.affiliation: Hematopathology Section, National Institutes of Health, Bethesda, MD.
authors.forename: M
authors.initials: M
authors.lastname: Raffeld
authors.forename: T
authors.initials: T
authors.lastname: Yano
authors.forename: A T
authors.initials: AT
authors.lastname: Hoang
authors.forename: B
authors.initials: B
authors.lastname: Lewis
authors.forename: H M
authors.initials: HM
authors.lastname: Clark
authors.forename: T
authors.initials: T
authors.lastname: Otsuki
authors.forename: C V
authors.initials: CV
authors.lastname: Dang
mesh_terms: D002051:Burkitt Lymphoma / Q000235:genetics*; D002898:Chromosomes, Human, Pair 8 / Q000648:ultrastructure*; D003062:Codon; D004252:DNA Mutational Analysis; D004273:DNA, Neoplasm / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000502:physiology; D005091:Exons; D005803:Genes, Immunoglobulin; D016259:Genes, myc; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000235:genetics*; D009363:Neoplasm Proteins / Q000737:chemistry* / Q000235:genetics / Q000502:physiology; D009687:Nuclear Proteins / Q000502:physiology; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D017434:Protein Structure, Tertiary; D016271:Proto-Oncogene Proteins c-myc / Q000737:chemistry* / Q000235:genetics / Q000502:physiology; D050720:Retinoblastoma-Like Protein p107; D035181:TATA-Box Binding Protein; D014157:Transcription Factors / Q000502:physiology; D015533:Transcriptional Activation; D014178:Translocation, Genetic; D014407:Tumor Cells, Cultured
chemical_list: D003062:Codon; D004273:DNA, Neoplasm; D004268:DNA-Binding Proteins; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D016271:Proto-Oncogene Proteins c-myc; D050720:Retinoblastoma-Like Protein p107; D035181:TATA-Box Binding Protein; D014157:Transcription Factors