title: [The effect of etimizol on the glycosaminoglycan level in patients with osteoarthrosis deformans].
abstract: Aetymizolum was studied for its efficacy in the treatment of patients with osteoarthrosis. The results obtained suggest that aethymizolum is capable of correcting the levels of glycosaminoglucans in the patients' blood serum. With the content of the latter being dependent upon the degree of the articular cartilage destruction in osteoarthrosis deformans, it is suggested that aethymizolum while being endowed with reparative and membrane stabilizing properties may at the same time influence the articular cartilage metabolism and decrease the intensity of the destruction of the later. Effect of aethymizolum is more pronounced in mono-oligoarthrosis and polyosteoarthrosis as well as in stages II and III of the disease course. Conventional therapies (indomethacin, humisolum, Fibs, physiotherapeutic procedures, remedial gymnastics, massage) have no effect on these parameters.
authors.forename: Ie M
authors.initials: IeM
authors.lastname: Neĭko
authors.forename: L V
authors.initials: LV
authors.lastname: Hlushko
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Holovach
authors.forename: R I
authors.initials: RI
authors.lastname: Iatsyshyn
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D005042:Etimizol / Q000627:therapeutic use*; D005260:Female; D006025:Glycosaminoglycans / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000097:blood / Q000188:drug therapy*
chemical_list: D006025:Glycosaminoglycans; D005042:Etimizol
vernacular_title: Vplyv etymizolu na riven' hlikozaminohlikaniv u khvorykh na deformuiuchyĭ osteoartroz.