[Modelling the general relative risk models in case-control studies of primary hepatocellular carcinoma].
This paper was to analyse the effect of risk factors of primary hepatocellular carcinoma (PHC). The analysis was carried on using the family of relative risk functions to asses which scale could better explain the risk structure underlying the data. The results showed that the risk factors of PHC in south area of China were HBV infection, family history of PHC, drank pond-ditch water, while the risk factors of PHC in north area were HBV infection, family history of PHC, history of hepatitis, drank alcohol. The results suggested that the combined effect of risk factors was near to multiplicative. Being able to discriminate between risk structures has important implications on causal interpretation and public health practice.
Zhao
N
N
Department of Epidemiology, Shanghai Medical University.
Yu
S Z
SZ
Sun
W M
WM
D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000209:etiology* / Q000821:virology; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D006509:Hepatitis B; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000821:virology; D016017:Odds Ratio; D012044:Regression Analysis; D012307:Risk Factors