Long-standing remission after 25-OH D3 treatment in a case of chronic myelomonocytic leukaemia.
This report describes a case of chronic myelomonocytic leukaemia (CMML) in whom a complete remission was achieved and sustained 15 months after treatment with 25-OH vitamin D3. No side-effects were observed. Although vitamin D1 has been used in the treatment of myelodysplastic syndromes, to our knowledge this is the first case of long-standing remission in a patient with CMML. This 'differentiation therapy' might be considered as a possible alternative in the management of this disease.
Mellibovsky
L
L
Servei de Medicina Interna, Hospital de l'Esperança, Universitat Autònoma de Barcelona, Spain.
Díez
A
A
Aubia
J
J
Nogues
X
X
Pérez-Vila
E
E
Serrano
S
S
Recker
R R
RR
D000368:Aged; D002112:Calcifediol / Q000627:therapeutic use*; D006801:Humans; D015477:Leukemia, Myelomonocytic, Chronic / Q000188:drug therapy*; D008297:Male; D012074:Remission Induction
D002112:Calcifediol