Salvage chemotherapy with pentostatin in prolymphocytic leukemia.
We report 4 cases of prolymphocytic leukemia (PLL) resistant to conventional chemotherapy that were treated with pentostatin. We obtained 1 complete remission (CR) and 2 partial remissions (PR). Our data confirm the effectiveness of this drug in the treatment of prolymphocytic leukemia.
Pagano
L
L
Istituto di Semeiotica Medica, Università Cattolica del Sacro Cuore, Roma, Italy.
Ortu-La Barbera
E O
EO
Voso
M T
MT
Zollino
M
M
Laurenti
L
L
Marra
R
R
Leone
G
G
D000368:Aged; D000369:Aged, 80 and over; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015463:Leukemia, Prolymphocytic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D015649:Pentostatin / Q000627:therapeutic use*; D012074:Remission Induction; D016879:Salvage Therapy
D015649:Pentostatin