Hereditary sensory neuropathy with sensorineural deafness and early-onset dementia.
We report a kindred with autosomal dominantly inherited sensory neuropathy associated with sensorineural hearing loss and early-onset dementia. This kindred provides further evidence of the clinical variability among kindreds with hereditary sensory neuropathy, suggesting genetic heterogeneity.
Wright
A
A
Department of Neurology, Mayo Clinic, Rochester, MN.
Dyck
P J
PJ
D000328:Adult; D017668:Age of Onset; D003704:Dementia / Q000235:genetics* / Q000503:physiopathology; D006319:Hearing Loss, Sensorineural / Q000235:genetics* / Q000503:physiopathology; D009477:Hereditary Sensory and Autonomic Neuropathies / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D008297:Male; D010375:Pedigree; D013497:Sural Nerve / Q000473:pathology