Synthetic biological response modifiers. Part II. Synthesis and immunomodulatory properties of some: N2-[omega-(pyrimidin-1-yl)carboxyalkyl]-L-arginines.
The synthesis and chemical and physical properties of some N2-[omega-(pyrimidin-1-yl)carboxyalkyl]-L-arginines are here described. Experiments of immunopharmacological evaluations are also described.
Stradi
R
R
Istituto di Chimica Organica, Facoltà di Farmacia, Università degli Studi di Milano, Italy.
Pini
E
E
Rossi
E
E
Cornaglia Ferraris
P
P
D000276:Adjuvants, Immunologic / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D001120:Arginine / Q000031:analogs & derivatives*; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015850:Interleukin-6 / Q000378:metabolism; D051379:Mice; D010920:Placenta / Q000187:drug effects; D013329:Structure-Activity Relationship; D014498:Uracil / Q000031:analogs & derivatives
D000276:Adjuvants, Immunologic; D007155:Immunologic Factors; D015850:Interleukin-6; D014498:Uracil; D001120:Arginine