[Benefits and risks of topical steroids in childhood].
Inhaled glucocorticosteroids have become the cornerstone mode of anti-inflammatory treatment in children, especially with bronchial asthma. Many publications document the clinical efficacy of inhaled steroids and an increasing number of authors point out the possible systemic effects of topical steroids, such as effects on growth, impaired bone metabolism and adrenal suppression. The goal of this review article is to summarize published data. The author stresses possible relevant side effects in relation to dose and inhalation technique and focuses on the most appropriate indications and therapeutic modalities of inhaled steroids. The article yields valuable information for both practitioners and clinicians which will assist them in administering inhaled steroids and in discussing questions of safety with medical professionals and laymen.
Sennhauser
F H
FH
Pädiatrische Pneumologie, Ostschweizerisches Kinderspital St. Gallen.
D000280:Administration, Inhalation; D000287:Administration, Topical; D000293:Adolescent; D000302:Adrenal Cortex / Q000187:drug effects; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001249:Asthma / Q000188:drug therapy* / Q000191:economics; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism; D001993:Bronchodilator Agents / Q000627:therapeutic use; D019819:Budesonide; D002648:Child; D002675:Child, Preschool; D005938:Glucocorticoids; D006128:Growth / Q000187:drug effects; D006801:Humans; D007223:Infant; D011282:Pregnenediones / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D005938:Glucocorticoids; D011282:Pregnenediones; D019819:Budesonide
Nutzen und Risiko topischer Steroide im Kindesalter.