[Ventral and posterior expression of the homeo box gene eve1 in zebrafish (Brachydanio rerio) is repressed in dorsalized embryos].
We have identified and characterized the zebrafish eve1 homeo box gene, a member of the Drosophila even-skipped (eve) gene family. eve1 is expressed in the most posterior part of the tail bud during somitogenesis. During gastrulation, transcripts are confined to ventral and lateral cells of the marginal zone of the embryo. We show that LiCl, known to dorsalize Xenopus embryos, has the same effect in zebrafish embryos. In LiCl-treated embryos, eve1 transcripts are completely absent, suggesting that eve1 marks the ventral specification of mesoderm in zebrafish gastrulae.
Joly
J S
JS
Institut Pasteur, Paris.
Maury
M
M
Joly
C
C
Boulekbache
H
H
Condamine
H
H
D000818:Animals; D005775:Gastrula / Q000187:drug effects; D015870:Gene Expression / Q000187:drug effects; D005801:Genes, Homeobox / Q000235:genetics*; D018021:Lithium Chloride / Q000494:pharmacology; D015027:Zebrafish / Q000196:embryology
D018021:Lithium Chloride
L'expression ventrale et postérieure du gène à homéoboîte eve1 de poisson-zèbre (Brachydanio rerio) est réprimée dans les embryons dorsalisés.