Cyclosporine and 6-mercaptopurine in pediatric inflammatory bowel disease.
After failure of medical therapy, children with refractory inflammatory bowel disease may require surgical intervention. In this article the authors describe one child in whom, after traditional therapies for refractory ulcerative colitis failed, full remission of the disease occurred after the addition of 6-mercaptopurine and cyclosporine A to her medical regimen. 6-Mercaptopurine has been used with increasing frequency in refractory inflammatory bowel disease; the use of cyclosporine A for this condition is still under investigation.
La Tulippe Naccarini
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Minor
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D002648:Child; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003131:Combined Modality Therapy; D016572:Cyclosporine / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*; D015122:Mercaptopurine / Q000008:administration & dosage*; D008775:Methylprednisolone / Q000008:administration & dosage; D010289:Parenteral Nutrition, Total; D012460:Sulfasalazine / Q000008:administration & dosage
D012460:Sulfasalazine; D016572:Cyclosporine; D015122:Mercaptopurine; D008775:Methylprednisolone