title: [Bladder tumor associated with von Recklinghausen's neurofibromatosis: a case report].
abstract: A 47-year-old female was admitted to our hospital complaining of macrohematuria. The patient had a history of von Recklinghausen's disease. Her skin showed multiple cafe-au-lait spots and neurofibromatosis. Thorough examinations were done. Urine cytology was positive. Intravenous pyelography and cystography demonstrated an irregular wall of the bladder. A computerized tomographic scan demonstrated a 7 cm nodular mass. Cystoscopy revealed a papillary tumor on the right lateral and anterior wall of the bladder. She was diagnosed as having a bladder tumor in von Recklinghausen's neurofibromatosis. Total cystectomy was performed. Histopathological diagnosis was transitional cell carcinoma with squamous cell carcinoma (Grade III, pT3N2N0). Fifty three cases of von Recklinghausen's disease in the literature were accompanied with malignancy.
authors.affiliation: Department of Urology, Zenshyukai Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Jimbo
authors.forename: Y
authors.initials: Y
authors.lastname: Totsuka
authors.forename: T
authors.initials: T
authors.lastname: Mashimo
authors.forename: T
authors.initials: T
authors.lastname: Umeyama
authors.forename: H
authors.initials: H
authors.lastname: Uehara
authors.forename: T
authors.initials: T
authors.lastname: Shinozaki
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D009456:Neurofibromatosis 1 / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*