Glutamate receptor phosphorylation and synaptic plasticity.
The recent findings that glutamate receptors are phosphorylated and functionally modulated by protein kinases has provided evidence that phosphorylation of these receptors may play a critical role in mechanisms of synaptic plasticity.
Roche
K W
KW
Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2185.
Tingley
W G
WG
Huganir
R L
RL
D000818:Animals; D006801:Humans; D009473:Neuronal Plasticity; D010744:Phosphoric Monoester Hydrolases / Q000502:physiology; D010766:Phosphorylation; D011494:Protein Kinases / Q000502:physiology; D018091:Receptors, AMPA / Q000378:metabolism; D017470:Receptors, Glutamate / Q000378:metabolism*; D018092:Kainic Acid Receptors / Q000378:metabolism; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism; D013569:Synapses / Q000502:physiology*
D010744:Phosphoric Monoester Hydrolases; D011494:Protein Kinases; D018091:Receptors, AMPA; D017470:Receptors, Glutamate; D018092:Kainic Acid Receptors; D016194:Receptors, N-Methyl-D-Aspartate