title: Neuroleptic exposure following inpatient treatment of acute mania with lithium and neuroleptic.
abstract: The authors examined continued neuroleptic exposure following inpatient treatment of mania with neuroleptics and lithium through structured chart review of 40 consecutive patients. At discharge, patients were receiving a mean of 793 mg/day (SD = 695) chlorpromazine equivalents; 6 months later they were receiving a mean of 634 mg/day (SD = 684). This decrease was statistically significant, but the patients' ongoing neuroleptic exposure remained substantial.
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.
authors.forename: M J
authors.initials: MJ
authors.lastname: Sernyak
authors.forename: R A
authors.initials: RA
authors.lastname: Griffin
authors.forename: R M
authors.initials: RM
authors.lastname: Johnson
authors.forename: H R
authors.initials: HR
authors.lastname: Pearsall
authors.forename: B E
authors.initials: BE
authors.lastname: Wexler
authors.forename: S W
authors.initials: SW
authors.lastname: Woods
mesh_terms: D000328:Adult; D000359:Aftercare; D000368:Aged; D000553:Ambulatory Care; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D001714:Bipolar Disorder / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D008094:Lithium / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D014150:Antipsychotic Agents; D008094:Lithium