[Effects of iontophoretic application of hydrogen ion on the spontaneous discharge of the nucleus paragigantocellularis lateralis neurons in brainstem slices in rats].
The effects of iontophoretic application of H- (acid NS) on the spontaneous discharge of nucleus paragigantocellularis lateralis (PGCL) neurons were studied in brainstem slice in rat with multibarrel microelectrode techniques. Most of the PGCL neurons tested (18/20, 90%) showed an excitatory response to H+ and the response was dose dependent, but none was inhibited. The results suggested that there were H+ sensitive cells in PGCL and these cells may be involved in central chemoreception.
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D000818:Animals; D001933:Brain Stem / Q000502:physiology*; D004594:Electrophysiology; D007478:Iontophoresis; D008526:Medulla Oblongata / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D011522:Protons; D051381:Rats
D011522:Protons