Chronic renal dysfunction in hemorrhagic fever with renal syndrome patients.
During the last 9 years, 32 cases of hemorrhagic fever with renal syndrome (HFRS) have been diagnosed in our institution. Seven patients died. Twenty-three patients were discharged healthy while in another 2 some degree of renal dysfunction, which remained stable 12-15 months later, was evident. In 12 out of the 23 healthy individuals thorough examination of renal function was performed 1-5 years after their discharge. Three out of the 12 had renal tubular acidosis (RTA) type I (distal), complete or incomplete, and 2 (1 of whom also had incomplete RTA) had reduced urine concentrating ability. The development of chronic renal dysfunction was independent of the clinical severity of the acute illness.
Elisaf
M
M
Department of Internal Medicine, Medical School, University of Ioannina, Greece.
Korakis
H
H
Siamopoulos
K C
KC
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006115:Greece / Q000453:epidemiology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007671:Kidney Concentrating Ability; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000209:etiology*; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D013997:Time Factors