The place of alpha blockers in the treatment of hypertension.
Alpha 1 adrenoceptor antagonists are safe, effective, well tolerated drugs which can be used alone or in combination with other drug groups in a wide range of hypertensive patients. Alpha 1 blockers not only lower blood pressure but may improve insulin sensitivity and the adverse lipid profile in many hypertensive patients. In addition to causing few side effects, alpha 1 blockers are not contra-indicated in patients with associated cardiovascular or respiratory disease. Alpha 1 blockers offer the potential to improve the risk factor profile more than conventional antihypertensive drugs.
Reid
J L
JL
Department of Medicine and Therapeutics, Western Infirmary, Glasgow, Scotland.
D000317:Adrenergic alpha-Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism; D008055:Lipids / Q000097:blood
D000317:Adrenergic alpha-Antagonists; D008055:Lipids