[A comparative evaluation of the antidepressive activity of different beta-adrenoblockaders].
A chronobiological evaluation of the forced swimming test in rats treated with propranolol has shown that beta-adrenoblockers have antidepressive properties. This is true for oxprenolol which shows less pronounced affects. Nadolol that does not readily cross the blood-brain barrier insignificantly changes swimming behavior in the animals.
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D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D002909:Chronobiology Phenomena / Q000187:drug effects; D008297:Male; D009248:Nadolol / Q000494:pharmacology; D010096:Oxprenolol / Q000494:pharmacology; D005082:Physical Exertion / Q000187:drug effects; D051381:Rats; D013550:Swimming; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D000928:Antidepressive Agents; D009248:Nadolol; D010096:Oxprenolol
Sravnitel'naia otsenka antidepressivnoĭ aktivnosti razlichnykh beta-adrenoblokatorov.