title: [Nootropic drugs potentiate nerve cell responses evoked by NMDA-glutamate receptor activation].
abstract: The nootropic drugs--nootropil, aethimizol, diethylaminoethanol, and ambocarb diminished of amnesia of active avoidance habit evoked by maximal electroconvulsive shock in the rats. At the same time tested nootropic drugs potentiated the frog spinal motoneurons responses mediated by NMDA, but not non NMDA glutamate receptors activation. It was discussed the role of NMDA-potentiating nootropic drugs action in their anti-amnestic action.
authors.forename: I I
authors.initials: II
authors.lastname: Abramets
authors.forename: P V
authors.initials: PV
authors.lastname: Andreev
authors.forename: I V
authors.initials: IV
authors.lastname: Komissarov
authors.forename: I M
authors.initials: IM
authors.lastname: Samoĭlovich
authors.forename: A V
authors.initials: AV
authors.lastname: Titievskiĭ
mesh_terms: D000647:Amnesia / Q000188:drug therapy; D000818:Animals; D001224:Aspartic Acid / Q000494:pharmacology; D004597:Electroshock; D005971:Glutamates / Q000494:pharmacology; D018698:Glutamic Acid; D008564:Membrane Potentials / Q000187:drug effects; D009046:Motor Neurons / Q000187:drug effects*; D018377:Neurotransmitter Agents / Q000494:pharmacology; D011619:Psychotropic Drugs / Q000494:pharmacology*; D011898:Ranidae; D051381:Rats; D017470:Receptors, Glutamate / Q000187:drug effects*; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects*; D013116:Spinal Cord / Q000166:cytology / Q000187:drug effects
chemical_list: D005971:Glutamates; D018377:Neurotransmitter Agents; D011619:Psychotropic Drugs; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate; D001224:Aspartic Acid; D018698:Glutamic Acid
vernacular_title: Nootropy potentsiruiut otvety nervnykh kletok, vyzyvaemye aktivatsieĭ NMDA-glutamatnykh retseptorov.