title: Induction of a 60-kDa heat shock protein in rat pancreas by water-immersion stress.
abstract: 1. In this study, expression of a 60-kDa heat shock protein in rat pancreas was investigated before and after water-immersion stress, which has been known as an exacerbation factor of caerulein-induced pancreatitis in rats, by Western blot. 2. A 60-kDa heat shock protein increased after water-immersion stress in both soluble and insoluble fractions of the pancreas. 3. Serum amylase level and pancreas weight did not increase after water-immersion. 4. No pathologic alteration was observed in the pancreas after water-immersion.
authors.affiliation: First Department of Internal Medicine, Akita University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Otaka
authors.forename: H
authors.initials: H
authors.lastname: Itoh
authors.forename: T
authors.initials: T
authors.lastname: Kuwabara
authors.forename: A
authors.initials: A
authors.lastname: Zeniya
authors.forename: S
authors.initials: S
authors.lastname: Fujimori
authors.forename: Y
authors.initials: Y
authors.lastname: Tashima
authors.forename: O
authors.initials: O
authors.lastname: Masamune
mesh_terms: D000818:Animals; D002108:Ceruletide; D018834:Chaperonin 60; D006360:Heat-Shock Proteins / Q000096:biosynthesis*; D007101:Immersion; D008297:Male; D010179:Pancreas / Q000378:metabolism*; D010195:Pancreatitis / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D013312:Stress, Physiological / Q000378:metabolism*; D014867:Water
chemical_list: D018834:Chaperonin 60; D006360:Heat-Shock Proteins; D014867:Water; D002108:Ceruletide