title: In situ hybridization study of kappa-opioid receptor mRNA in the rat brain.
abstract: Distribution of kappa-opioid receptor mRNA in rat brain was examined by in situ hybridization technique. kappa-Opioid receptor mRNA was expressed in various brain regions, especially intensely in the neocortex (layer V and VI), caudate-putamen, nucleus accumbens, preoptic area, paraventricular thalamic nucleus, amygdala, several nuclei of hypothalamus, ventral tegmental area and substantia nigra pars compacta.
authors.affiliation: Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Minami
authors.forename: Y
authors.initials: Y
authors.lastname: Hosoi
authors.forename: T
authors.initials: T
authors.lastname: Toya
authors.forename: Y
authors.initials: Y
authors.lastname: Katao
authors.forename: K
authors.initials: K
authors.lastname: Maekawa
authors.forename: S
authors.initials: S
authors.lastname: Katsumata
authors.forename: K
authors.initials: K
authors.lastname: Yabuuchi
authors.forename: T
authors.initials: T
authors.lastname: Onogi
authors.forename: M
authors.initials: M
authors.lastname: Satoh
mesh_terms: D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D000818:Animals; D001345:Autoradiography; D001923:Brain Chemistry / Q000502:physiology*; D004399:Dynorphins / Q000494:pharmacology; D017403:In Situ Hybridization; D011759:Pyrrolidines / Q000494:pharmacology; D015347:RNA Probes; D016372:RNA, Antisense / Q000096:biosynthesis; D012333:RNA, Messenger / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D017473:Receptors, Opioid, kappa / Q000096:biosynthesis*
chemical_list: D011759:Pyrrolidines; D015347:RNA Probes; D016372:RNA, Antisense; D012333:RNA, Messenger; D017473:Receptors, Opioid, kappa; D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D004399:Dynorphins