Neuroleptic exposure following inpatient treatment of acute mania with lithium and neuroleptic.
The authors examined continued neuroleptic exposure following inpatient treatment of mania with neuroleptics and lithium through structured chart review of 40 consecutive patients. At discharge, patients were receiving a mean of 793 mg/day (SD = 695) chlorpromazine equivalents; 6 months later they were receiving a mean of 634 mg/day (SD = 684). This decrease was statistically significant, but the patients' ongoing neuroleptic exposure remained substantial.
Sernyak
M J
MJ
Department of Psychiatry, Yale University School of Medicine, New Haven, Conn.
Griffin
R A
RA
Johnson
R M
RM
Pearsall
H R
HR
Wexler
B E
BE
Woods
S W
SW
D000328:Adult; D000359:Aftercare; D000368:Aged; D000553:Ambulatory Care; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D001714:Bipolar Disorder / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D008094:Lithium / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D014150:Antipsychotic Agents; D008094:Lithium