title: Dose response in the treatment of breast cancer.
abstract: We present evidence that drugs that are effective in causing regression of metastatic breast cancer in a dose-dependent fashion also cause a dose-dependent reduction of cytokines produced by the immune system. This may be an important factor in the occasional induction of a complete remission.
authors.affiliation: Ottawa General Hospital, Ontario, Canada.
authors.forename: T H
authors.initials: TH
authors.lastname: Stewart
authors.forename: M W
authors.initials: MW
authors.lastname: Retsky
authors.forename: S C
authors.initials: SC
authors.lastname: Tsai
authors.forename: S
authors.initials: S
authors.lastname: Verma
mesh_terms: D016026:Bone Marrow Transplantation; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000556:secondary / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D016207:Cytokines / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D011278:Pregnanes / Q000627:therapeutic use; D012074:Remission Induction
chemical_list: D016207:Cytokines; D011278:Pregnanes