[Beta-blockers and plasma lipids].
Beta-blockers are frequently used in the treatment of hypertension. However their long term use has been associated with an increase of serum triglycerides and a decrease of HLD-cholesterol concentrations which could diminish the benefit drawn from their hypotensive effect. The effect on lipid metabolism is less unfavourable when beta-blockers exert an intrinsic sympathomimetic activity or are said to be cardioselective. Mechanisms involved are complex and poorly understood.
Soulier
C
C
Service de Pharmacologie-Toxicologie, Hôpital Dupuytren, Limoges.
Merle
L
L
D000319:Adrenergic beta-Antagonists / Q000145:classification / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D008055:Lipids / Q000097:blood*; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D008055:Lipids
Bêta-bloquants et lipides plasmatiques.