[Beta blockers in stable angina pectoris].
A concise overview of the pathophysiologic mechanisms of stable angina pectoris and the attempt to deduce its rational therapy presented. The possible mode of action of are beta-adrenergic blockers and calcium entry blockers is described. It becomes evident that the results of clinical trials do not perfectly correspond to the present pathophysiological models. The pharmacological properties of beta-adrenergic blockers are summarized with regard to the therapy of stable angina pectoris. The value of a combination of beta-adrenergic blockers and calcium entry blockers in the therapy of stable angina pectoris is discussed. Finally, the prognostic importance of silent ischemia with regard to stable angina pectoris and the possible therapeutic consequences are discussed.
Fluri
M
M
Departement Medizin, Universitätsklinik, Bern.
Meier
B
B
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D002121:Calcium Channel Blockers / Q000008:administration & dosage; D003326:Coronary Circulation / Q000187:drug effects; D004359:Drug Therapy, Combination; D006801:Humans; D017202:Myocardial Ischemia / Q000188:drug therapy; D011943:Receptors, Adrenergic, beta / Q000187:drug effects
D000319:Adrenergic beta-Antagonists; D002121:Calcium Channel Blockers; D011943:Receptors, Adrenergic, beta
Betablocker bei stabiler Angina pectoris.