Successful treatment of deglutition syncope with oral beta-adrenergic blockade.
A case of deglutition syncope of 20 years' duration in a patient without cardiac or esophageal disease is presented. The therapeutic efficacy of beta-blockade is documented by symptomatic improvement, repeat esophageal balloon inflation and tilt-table testing. This suggests the Bezold-Jarisch reflex or sympathetic nervous system may be involved in the pathogenesis of deglutition syncope.
Marshall
T M
TM
Division of Cardiology, University of British Columbia, Vancouver.
Mizgala
H F
HF
Yeung-Lai-Wah
J A
JA
Steinbrecher
U P
UP
D000284:Administration, Oral; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D003680:Deglutition Disorders / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013575:Syncope / Q000188:drug therapy / Q000209:etiology*; D014666:Vasomotor System / Q000187:drug effects / Q000503:physiopathology
D000319:Adrenergic beta-Antagonists