title: Transcriptional regulation of T-cell genes during T-cell development.
abstract: The expression of many T cell specific genes has been shown to be regulated at the transcriptional level. Recent studies of T-cell specific promoters and enhancers have allowed the identification of a number of transcription factors that appear to play distinct but complementary roles in regulating gene expression during T-cell development and activation.
authors.affiliation: Howard Hughes Medical Institute, Chicago.
authors.forename: J M
authors.initials: JM
authors.lastname: Leiden
authors.forename: C B
authors.initials: CB
authors.lastname: Thompson
mesh_terms: D000818:Animals; D001483:Base Sequence; D002843:Chromatin / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology*; D005801:Genes, Homeobox / Q000502:physiology; D018257:Helix-Loop-Helix Motifs / Q000502:physiology; D006609:High Mobility Group Proteins / Q000502:physiology; D007107:Immune System / Q000254:growth & development*; D008969:Molecular Sequence Data; D013601:T-Lymphocytes / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*; D016335:Zinc Fingers / Q000235:genetics
chemical_list: D002843:Chromatin; D006609:High Mobility Group Proteins; D014157:Transcription Factors