title: The role of dermabrasion and chemical peels in the treatment of patients with xeroderma pigmentosum.
abstract: We describe our experience with two patients with xeroderma pigmentosum who underwent periodic trichloroacetic acid chemical peels. One also received a full-face dermabrasion. The effect of chemical peeling was more transient than dermabrasion but was associated with less morbidity. Both chemical peeling and dermabrasion provided a prophylactic effect against the development of skin malignancies; the latter had a more pronounced effect.
authors.affiliation: Department of Dermatology, University of Michigan, Ann Arbor.
authors.forename: B R
authors.initials: BR
authors.lastname: Nelson
authors.forename: D J
authors.initials: DJ
authors.lastname: Fader
authors.forename: M
authors.initials: M
authors.lastname: Gillard
authors.forename: S R
authors.initials: SR
authors.lastname: Baker
authors.forename: T M
authors.initials: TM
authors.lastname: Johnson
mesh_terms: D000293:Adolescent; D002280:Basal Cell Carcinoma / Q000517:prevention & control; D002294:Carcinoma, Squamous Cell / Q000517:prevention & control; D002615:Chemexfoliation / Q000009:adverse effects; D002648:Child; D003869:Dermabrasion / Q000009:adverse effects; D005153:Facial Neoplasms / Q000517:prevention & control / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D012878:Skin Neoplasms / Q000517:prevention & control / Q000601:surgery*; D014238:Trichloroacetic Acid / Q000627:therapeutic use*; D014983:Xeroderma Pigmentosum / Q000601:surgery*
chemical_list: D014238:Trichloroacetic Acid