title: Analysis of a 70 kb region on the right arm of yeast chromosome II.
abstract: In the framework of the EC programme for sequencing yeast chromosome II, we have determined the nucleotide sequence of a 70 kb region. Subsequent analysis revealed 35 open reading frames, 14 of which correspond to known yeast genes. From structural parameters and/or similarity searches with entries in the current data libraries, a preliminary functional assessment of several of the putative novel gene products can be made. The gene density in this region amounts to one gene in 1.98 kb. Coding regions occupy 75% of the total DNA sequence. Within the intergenic regions, potential regulatory elements can be predicted. The data obtained here may serve as a basis for a more detailed biochemical analysis of the novel genes.
authors.affiliation: Institut für Physiologische Chemie, Universität München, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Mannhaupt
authors.forename: R
authors.initials: R
authors.lastname: Stucka
authors.forename: S
authors.initials: S
authors.lastname: Ehnle
authors.forename: I
authors.initials: I
authors.lastname: Vetter
authors.forename: H
authors.initials: H
authors.lastname: Feldmann
mesh_terms: D000595:Amino Acid Sequence; D001482:Base Composition; D001483:Base Sequence; D015825:Chromosomes, Fungal; D005800:Genes, Fungal; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D012441:Saccharomyces cerevisiae / Q000235:genetics*