title: [New pharmacodynamic effects of gidazepam and befol in patients with cardiac arrhythmias].
abstract: The new Russian drugs gidazepam, a tranquilizer, and befol, an antidepressant, show not only their psychotropic action, but change cardiac electrophysiological function and produce antiarrhythmic effects, which allows them to be used in the treatment of various cardiac arrhythmias. The antiarrhythmic effect of the psychopharmacological agents is largely shown in patients with ventricular premature contraction and paroxysmal tachycardias in the presence of neurocirculatory dystonia, as well as with great deviations of the electrophysiological properties of the cardiac conduction system from the their mean values, by promoting their normalization. The antiarrhythmic effect of gidazepam is higher than that of befol in both patients with neurocirculatory dystonia and those with coronary heart disease.
authors.forename: V V
authors.initials: VV
authors.lastname: Skibitskiĭ
authors.forename: S G
authors.initials: SG
authors.lastname: Kanorskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D014151:Anti-Anxiety Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D001549:Benzamides / Q000494:pharmacology* / Q000627:therapeutic use; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000494:pharmacology* / Q000627:therapeutic use; D004311:Double-Blind Method; D004341:Drug Evaluation; D015716:Electrocardiography, Ambulatory / Q000187:drug effects; D005260:Female; D006801:Humans; D008950:MMPI; D008297:Male; D008875:Middle Aged; D009025:Morpholines / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D014151:Anti-Anxiety Agents; D000889:Anti-Arrhythmia Agents; D000928:Antidepressive Agents; D001549:Benzamides; D001570:Benzodiazepinones; D009025:Morpholines; D001569:Benzodiazepines; C059049:befol; C077010:gidazepam
vernacular_title: O novykh farmakologicheskikh éffektov gidazepama i befola u bol'nykh s aritmiiami serdtsa.