Evaluation of some pharmacological activities of Eugenia uniflora L.
In view of the extensive use of Eugenia uniflora in folk medicine, different extracts of dried and fresh leaves of the plant were assayed to test its possible pharmacological activities. The infusion of fresh leaves had a highly significant anti-inflammatory effect when administered p.o. to rats 1 h before subplantar injection of carrageenin. The infusion increased the pentobarbital sleeping time and also had an effect on intestinal transit, and had no acute toxic effect. No analgesic or antimicrobial activities were observed with any of the extracts used.
Schapoval
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EE
Graduate Course in Pharmacy, Faculty of Pharmacy, UFRGS, Porto Alegre, RS, Brazil.
Silveira
S M
SM
Miranda
M L
ML
Alice
C B
CB
Henriques
A T
AT
D000284:Administration, Oral; D000698:Analgesia; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D004487:Edema / Q000188:drug therapy; D005772:Gastrointestinal Transit / Q000187:drug effects; D008297:Male; D051379:Mice; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D012890:Sleep / Q000187:drug effects
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts