Weekly treatment of psoriasis with a hydrocolloid dressing in combination with triamcinolone acetonide. A controlled comparative study.
In a within subject comparison, the efficacy and the tolerability of topical treatment with triamcinolone acetonide under a hydrocolloid dressing were compared with triamcinolone acetonide monotherapy, monotherapy with hydrocolloid dressing and triamcinolone acetonide under plastic occlusion. The clinical efficacy of hydrocolloid dressing as a monotherapy and the pronounced clinical efficacy of this occlusive in combination with triamcinolone acetonide were confirmed. Comparing the hydrocolloid dressing (Duoderm E) and the plastic semi-occlusive (Opsite IV 3000), we concluded that the tolerability of both approaches was similar. However, Duoderm E in conjunction with triamcinolone acetonide was highly effective, whereas Opsite IV 3000 in combination with this steroid only had an inconspicuous antipsoriatic potential.
van de Kerkhof
P C
PC
Department of Dermatology, University Hospital Nijmegen, The Netherlands.
Chang
A
A
van der Walle
H B
HB
van Vlijmen-Willems
I
I
Boezeman
J B
JB
Huigen-Tijdink
R
R
D000328:Adult; D047070:Bandages, Hydrocolloid; D003102:Colloids / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D009779:Occlusive Dressings; D011565:Psoriasis / Q000188:drug therapy / Q000628:therapy*; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
D003102:Colloids; D014222:Triamcinolone Acetonide