[The use of interferon in treating systemic lupus erythematosus].
We examined 55 SLE patients. By the treatment the patients entered 5 groups: groups I and II received gammaferon plus reaferon, groups III and IV received IFN plus cyclophosphamide and control group V received placvenil. Compared to controls, the best results were obtained in patients on gammaferon combined with cyclophosphamide. IFN preparations alone showed less pronounced effects. No changes were registered in the control group. We believe that IFN preparations demonstrated efficacy against SLE.
Egorova
O N
ON
Balabanova
R M
RM
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007371:Interferon-gamma / Q000627:therapeutic use*; D008180:Lupus Erythematosus, Systemic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D013997:Time Factors
D000305:Adrenal Cortex Hormones; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D007371:Interferon-gamma; D003520:Cyclophosphamide
Ispol'zovanie interferona v lechenii sistemnoĭ krasnoĭ volchanki.