title: Which plasma factors bring about disturbance of endothelial function in pre-eclampsia?
abstract: The characteristic pathophysiological changes in pre-eclampsia are thought to be related to abnormalities of the maternal vascular endothelium. We suggest that the blood components that affect the risk of such damage are very-low-density lipoproteins (VLDL), which injure the endothelium, and toxicity-preventing activity (the pl 5.6 form of plasma albumin), which protects against VLDL-induced injury.
authors.affiliation: Department of Internal Medicine, James H Quillen College of Medicine, East Tennessee State University, Johnson City.
authors.forename: B W
authors.initials: BW
authors.lastname: Arbogast
authors.forename: S C
authors.initials: SC
authors.lastname: Leeper
authors.forename: R D
authors.initials: RD
authors.lastname: Merrick
authors.forename: K E
authors.initials: KE
authors.lastname: Olive
authors.forename: R N
authors.initials: RN
authors.lastname: Taylor
mesh_terms: D002478:Cells, Cultured; D004730:Endothelium, Vascular / Q000502:physiology*; D005260:Female; D006801:Humans; D008079:Lipoproteins, VLDL / Q000097:blood; D011225:Pre-Eclampsia / Q000209:etiology / Q000503:physiopathology*; D011247:Pregnancy; D012709:Serum Albumin / Q000502:physiology
chemical_list: D008079:Lipoproteins, VLDL; D012709:Serum Albumin