The role of homeobox genes in limb development.
Intensive study of the development of the vertebrate limb has led to a conceptual framework for understanding the specification of a limb primordium, the outgrowth of those cells and their organization and differentiation into a functional appendage. During the past few years, a number of homeobox-containing genes have been identified that are likely to play controlling roles in each of these events.
Morgan
B A
BA
Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.
Tabin
C J
CJ
D000818:Animals; D002642:Chick Embryo; D005121:Extremities / Q000196:embryology*; D005801:Genes, Homeobox