title: Outcome of stage I carcinoma of the breast at the University Hospital of the West Indies (1982-1988).
abstract: The 5-year survival data for 62 patients with Stage I breast cancer treated at the University Hospital of the West Indies (UHWI) between 1982 and 1988 were evaluated to determine which factors were affecting outcome. The overall survival rates (66.7%) were below those quoted from large multicentre studies from North America, Western Europe and Australasia. The most significant survival differences emerged in the subset of postmenopausal patients with clinically staged disease who fared worse than those with pathologically staged disease. These data suggest that clinical staging is inadequate for the management of Stage I breast cancer. Consistent pathological staging, utilization of other prognostic predictors, and systemic therapy on a more widespread scale may help to improve the clinical outcome.
authors.affiliation: Department of Pathology, U.W.I., Jamaica.
authors.forename: J P
authors.initials: JP
authors.lastname: Walters
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D003906:Developing Countries; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D007563:Jamaica / Q000453:epidemiology; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D015996:Survival Rate