title: Serum copper, zinc and copper/zinc ratio in males: influence of aging.
abstract: Apparently healthy free-living (non-hospitalized) men aged 8-89 years (n = 408) were studied to determine the effect of age on serum copper and zinc concentrations and the copper/zinc ratio. Mean values +/- S.D. for age, serum copper and zinc levels and the copper/zinc ratio were as follow: 41.9 +/- 22.9 years, 1.15 +/- 0.17 micrograms/ml, 0.93 +/- 0.14 micrograms/ml and 1.25 +/- 0.19, respectively. In the elderly subjects above 75 years, a marked increase in serum copper concentrations and the copper/zinc ratio as well as a decrease in serum zinc concentrations were observed. Serum copper concentrations and the copper/zinc ratio correlated positively with age (p < 0.0001).
authors.affiliation: Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic.
authors.forename: A
authors.initials: A
authors.lastname: Madarić
authors.forename: E
authors.initials: E
authors.lastname: Ginter
authors.forename: J
authors.initials: J
authors.lastname: Kadrabová
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood*; D002648:Child; D003300:Copper / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013054:Spectrophotometry, Atomic; D015032:Zinc / Q000097:blood*
chemical_list: D003300:Copper; D015032:Zinc