title: Bilateral large-cell calcifying Sertoli cell tumor of the testes with Peutz-Jeghers syndrome: a case report.
abstract: A 13-year-old boy with Peutz-Jeghers syndrome (PJs), gynecomastia, and bilateral multifocal testicular tumors is described. Histology of the testicular tissue disclosed large-cell calcifying Sertoli cell tumors. Females with PJs are known to be at increased risk of developing gonadal tumors. This case and a review of other reported cases suggest that males with PJs are also at risk for developing gonadal tumors.
authors.affiliation: Department of Anatomical Pathology, University of Pretoria, Republic of South Africa.
authors.forename: L
authors.initials: L
authors.lastname: Dreyer
authors.forename: W K
authors.initials: WK
authors.lastname: Jacyk
authors.forename: D J
authors.initials: DJ
authors.lastname: du Plessis
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D006177:Gynecomastia / Q000150:complications; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000473:pathology*; D009919:Orchiectomy; D010580:Peutz-Jeghers Syndrome / Q000150:complications*; D012707:Sertoli Cell Tumor / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013736:Testicular Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014463:Ultrasonography