Nitrite ion is not an active intermediate in the vascular metabolism of organic nitrates and organic nitrites to nitric oxide.
Kowaluk
E A
EA
Department of Pharmaceutics, School of Pharmacy, State University of New York at Buffalo 14260.
Chung
S J
SJ
Fung
H L
HL
D000818:Animals; D001711:Biotransformation; D002417:Cattle; D002463:Cell Membrane Permeability; D008861:Microsomes / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D009566:Nitrates / Q000378:metabolism* / Q000493:pharmacokinetics; D009569:Nitric Oxide / Q000378:metabolism* / Q000502:physiology; D009573:Nitrites / Q000378:metabolism* / Q000493:pharmacokinetics; D005996:Nitroglycerin / Q000378:metabolism / Q000493:pharmacokinetics; D012977:Sodium Nitrite / Q000378:metabolism / Q000493:pharmacokinetics; D013347:Subcellular Fractions / Q000378:metabolism
D009566:Nitrates; D009573:Nitrites; D009569:Nitric Oxide; D005996:Nitroglycerin; C018086:isobutyl nitrite; D012977:Sodium Nitrite