[Relationship between airway obstruction and inspiratory muscle function].
Measurement of Pimax (maximal static inspiratory mouth pressure), Pi (static inspiratory mouth pressure) and 5 routine pulmonary function tests, which inspect the degree of airway obstruction, was done in 157 patients with COPD and 55 normal subjects. The results indicated that along with the deterioration of COPD, the Pimax was getting decreased and the Pi/Pimax was getting increased. In the mild and moderate COPD groups, however, the Pi and Pi/Pimax showed no statistical significance, which was the only exception. Our results suggested that (1) the airway obstruction could reduce the inspiratory muscle strength; and (2) the Pi/Pimax might be useful in clinical practice for early diagnosis of inspiratory muscle insufficiency.
Yuna
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Luo
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He
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Zeng
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D000328:Adult; D000368:Aged; D000403:Airway Resistance; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000503:physiopathology*