Taxoids, a new class of antitumour agents of plant origin: recent results.
The taxoids are natural products isolated from the yew tree (Taxaceae). Certain compounds of this family possess interesting antitumour properties. The discovery of one such compound, taxol and the development of an even more active derivative, Taxotere, are described. Taxotere represents a major progress in the domain of cancer chemotherapy.
Potier
P
P
Institut de Chimie des Substances Naturelles, CNRS, Gif-sur-Yvette, France.
Guéritte-Voegelein
F
F
Guénard
D
D
D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use*; D000077143:Docetaxel; D006801:Humans; D015394:Molecular Structure; D017239:Paclitaxel / Q000031:analogs & derivatives / Q000627:therapeutic use; D013329:Structure-Activity Relationship; D043823:Taxoids
D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel; D017239:Paclitaxel