Latency increase of auditory-evoked potential component N1 predicts poor neuroleptic response in schizophrenic patients.
In a group of 33 acutely ill, previously unmedicated schizophrenic inpatients, the auditory-evoked potential components N1 and P2 were assessed and related to neuroleptic response measured as improvement of the BPRS score during a two-week neuroleptic treatment. N1 latency increase was found to be predictive for a poor neuroleptic response.
Adler
G
G
Central Institute for Mental Health, Unit Neurobiology of Functional Psychoses, Mannheim, Germany.
Markert
U
U
Gattaz
W F
WF
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
D014150:Antipsychotic Agents