title: Prevalence of fenbendazole resistance in ovine nematodes in north west India.
abstract: A survey was undertaken between March and September 1992 to assess the prevalence of fenbendazole resistance in sheep nematodes in 32 traditionally managed rural flocks and 22 intensively managed flocks on 3 farms. Fenbendazole, a commonly used anthelmintic was used at the recommended dose of 5 mg/kg body weight. Efficacy was determined on the basis of percentage reduction in strongyle faecal egg counts (FECR%) and larval cultures before and between 7 and 10 days after treatment. None of the traditionally managed rural flocks showed resistance and all had greater than 99% reduction in faecal egg counts after treatment. Of the 22 intensively managed flocks, however, 15 had slight fenbendazole resistance (between 60 and 90% reduction in egg counts) and 4 had severe resistance (less than 60% reduction).
authors.affiliation: Department of Veterinary Parasitology, CCS Haryana Agricultural University, India.
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: C L
authors.initials: CL
authors.lastname: Yadav
mesh_terms: D000822:Animal Husbandry / Q000379:methods; D000818:Animals; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D005273:Fenbendazole / Q000494:pharmacology* / Q000627:therapeutic use; D006189:Haemonchus / Q000187:drug effects*; D007194:India; D010270:Parasite Egg Count / Q000706:statistics & numerical data / Q000662:veterinary; D012756:Sheep / Q000469:parasitology*; D012757:Sheep Diseases / Q000188:drug therapy; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000662:veterinary; D014254:Trichostrongylus / Q000187:drug effects*
chemical_list: D005273:Fenbendazole