title: Carcinoma arising in thyroglossal remnants.
abstract: Three patients with a papillary carcinoma arising in a thyroglossal duct cyst are presented and the literature is reviewed. This rare malignancy is seen mostly in women between the ages of 20 and 50 years. The distribution of carcinoma subtypes differs from that of thyroid carcinomas and thyroglossal duct carcinoma is recognized as a primary tumour. The diagnosis is seldom made pre-operatively though especially in older patients with midline swellings in the neck the diagnosis should be considered. Sistrunk's operation is the treatment of choice. In this operation the cyst, the middle part of the hyoid bone and the thyroglossal duct are removed in continuity.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam.
authors.forename: P A
authors.initials: PA
authors.lastname: Van Vuuren
authors.forename: A J
authors.initials: AJ
authors.lastname: Balm
authors.forename: R T
authors.initials: RT
authors.lastname: Gregor
authors.forename: F J
authors.initials: FJ
authors.lastname: Hilgers
authors.forename: B M
authors.initials: BM
authors.lastname: Loftus
authors.forename: C C
authors.initials: CC
authors.lastname: Delprat
authors.forename: E J
authors.initials: EJ
authors.lastname: Rutgers
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006928:Hyoid Bone / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013955:Thyroglossal Cyst / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy