Pheochromocytoma with multiple islet cell carcinoma.
We reported a rare case of a 17-year-old female with pheochromocytoma associated with multiple islet cell carcinoma. Pheochromocytoma was identified in the right adrenal gland. Multiple pancreas tumours were demonstrated unpredictably in the diagnostic imaging of the pheochromocytoma. No other endocrinological neoplasm was observed in the pituitary, thyroid and parathyroid gland. The patient underwent right adrenalectomy and total pancreatectomy. Pheochromocytoma was benign, however, pancreas tumours were non-functioning islet cell tumours and histologically malignant. This combination is assumed to represent a mixed form of multiple endocrine neoplasia (MEN) 1 and MEN 2.
Tamasawa
N
N
Third Department of Internal Medicine, Hirosaki University School of Medicine, Aomori, Japan.
Terada
A
A
Kodama
T
T
Ishigame
M
M
Ishimaru
K
K
Hishida
R
R
Satoh
T
T
Takebe
K
K
Sasaki
M
M
Imamura
K
K
D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000097:blood / Q000150:complications* / Q000601:surgery / Q000652:urine; D000315:Adrenalectomy; D018273:Carcinoma, Islet Cell / Q000150:complications* / Q000473:pathology / Q000601:surgery; D002395:Catecholamines / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010673:Pheochromocytoma / Q000097:blood / Q000150:complications* / Q000601:surgery / Q000652:urine; D013156:Splenectomy
D002395:Catecholamines