Antidepressant principles of Valeriana fauriei roots.
A methanol extract of the roots of Valeriana fauriei (Valerianaceae), exhibited antidepressant activity in mice. The extract was fractioned, monitored by the activity, to afford alpha-kessyl alcohol as an active principle. The antidepressant activity of some guaiane and valerane types of sesquiterpenoids in the active fraction was also evaluated.
Oshima
Y
Y
Pharmaceutical Institute, Tohoku University, Sendai, Japan.
Matsuoka
S
S
Ohizumi
Y
Y
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D014632:Valerian / Q000737:chemistry*
D000928:Antidepressive Agents; D010936:Plant Extracts