Acute overdose of a new dopamine agonist, CV 205-502.
CV 205-502 is a new dopamine agonist used for hyperprolactinaemia. We report a case of acute overdose (one month treatment, i.e. 2.25 mg) in a 25-year-old male patient. Clinical symptoms were restricted to nausea and mild hypotension. Treatment consisting of ipeca cuanha, charcoal and intravenous fluids allowed a rapid, successful outcome. This case illustrates the particular features of CV 205-502 intoxication when compared to other dopamine agonists, pointing out the tolerance of the drug which can be considered for wider indications and safer prescriptions.
Tauveron
I
I
Service d'Endocrinologie, CHU, Clermont-Ferrand, France.
Gesta
J M
JM
Jalenques
I
I
Thieblot
P
P
D000328:Adult; D000634:Aminoquinolines / Q000506:poisoning*; D015259:Dopamine Agents / Q000506:poisoning*; D062787:Drug Overdose; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D008297:Male; D009325:Nausea / Q000139:chemically induced
D000634:Aminoquinolines; D015259:Dopamine Agents; C046650:quinagolide