title: [RFLP-PCR technique for exclusion of carrier status of the mutated Rb gene].
abstract: Molecular-genetic analysis of DNA by PCR-RFLP technique in a family with a case of unilateral retinoblastoma was performed. The carrier status of mutated Rb gene in a sister of proband was excluded on the basis of molecular analysis despite unsynonymous pedigree data.
authors.affiliation: Zakładu Genetyki i Patomorfologii Instytutu Patologii, Pomorskiej AM.
authors.forename: S
authors.initials: S
authors.lastname: Zajaczek
authors.forename: J
authors.initials: J
authors.lastname: Podolski
authors.forename: J
authors.initials: J
authors.lastname: Lubiński
authors.forename: A
authors.initials: A
authors.lastname: Rosławska
authors.forename: Z
authors.initials: Z
authors.lastname: Krzystolik
authors.forename: Z
authors.initials: Z
authors.lastname: Sagan
mesh_terms: D002675:Child, Preschool; D004273:DNA, Neoplasm / Q000032:analysis*; D005190:Family; D005260:Female; D016161:Genes, Retinoblastoma / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D008297:Male; D009154:Mutation; D010375:Pedigree; D012150:Polymorphism, Restriction Fragment Length; D012175:Retinoblastoma / Q000235:genetics*
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Technika RFLP-PCR w wykluczeniu nosicielstwa zmutowanego genu Rb.