Effect of simultaneous low level exposure of Pb and Cd on delta-ALAD and acetylcholinesterase activity in rats.
Dose dependent study was performed to identify subcritical level of Pb and Cd. Blood delta-ALAD activity was inhibited by (0.1 mg/kg body wt) of both lead and cadmium in isolation and combination, the extent of which increases with duration of exposure. Hepatic delta-ALAD activity however is less affected by Cd and Pb-Cd together than Pb alone. Erythrocyte acetylcholinesterase activity though decrease in all groups, is not significant.
Gupta
S
S
Department of Biochemistry, Faculty of Science, M.S. University of Baroda, India.
Bhosale
S
S
Pandya
K
K
D000110:Acetylcholinesterase / Q000187:drug effects*; D000818:Animals; D002104:Cadmium / Q000633:toxicity*; D007854:Lead / Q000633:toxicity*; D008297:Male; D000623:Porphobilinogen Synthase / Q000187:drug effects*; D051381:Rats
D002104:Cadmium; D007854:Lead; D000110:Acetylcholinesterase; D000623:Porphobilinogen Synthase