title: Differential effects of postingestive feedback on the reward value of sucrose and lateral hypothalamic stimulation in rats.
abstract: The effects of postingestive feedback on the value of intraoral sucrose and lateral hypothalamic (LH) stimulation were compared. Rats chose between a fixed LH stimulation train or a compound reward composed of the same stimulation train and an oral infusion of 1 M sucrose. The rats preferred the compound reward when postingestive feedback was reduced by opening a gastric cannula. However, when the cannula was closed, the compound was preferred only at the beginning of each session, and preference declined or reversed as consumption continued. A second experiment showed that the reduction in preference caused by closing the gastric cannula was not due to a punishing effect of the gastrointestinal load. This study suggests that postingestive signals modulate gustatory reward at a stage of processing before gustatory and brain stimulation rewards are combined.
authors.affiliation: Department of Psychology, Concordia University, Montreal, Quebec, Canada.
authors.forename: K L
authors.initials: KL
authors.lastname: Conover
authors.forename: P
authors.initials: P
authors.lastname: Shizgal
mesh_terms: D000818:Animals; D001070:Appetitive Behavior / Q000502:physiology*; D001931:Brain Mapping; D002755:Choice Behavior / Q000502:physiology; D004558:Electric Stimulation; D005246:Feedback / Q000502:physiology; D005518:Food Preferences / Q000502:physiology*; D007026:Hypothalamic Area, Lateral / Q000502:physiology*; D008297:Male; D009042:Motivation; D010153:Paired-Associate Learning / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012528:Satiety Response / Q000502:physiology*; D012653:Self Stimulation / Q000502:physiology*; D013649:Taste / Q000502:physiology*; D014882:Water-Electrolyte Balance / Q000502:physiology