title: Brain abscess due to infection with Entamoeba histolytica.
abstract: We successfully treated a serious case of Entamoeba histolytica infection showing brain abscess, meningitis, and liver abscess by oral administration of metronidazole, intramuscular injection of dehydroemetine, and drainage of the brain abscess. The diagnosis of amebic brain abscess was based on a combination of clinical symptoms and signs, computed tomography and magnetic resonance imaging findings, a positive serologic test result for E. histolytica, a dramatic response to anti-amebic drugs after an ineffective therapeutic history with antibacterial drugs, and application of the polymerase chain reaction method.
authors.affiliation: Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ohnishi
authors.forename: M
authors.initials: M
authors.lastname: Murata
authors.forename: H
authors.initials: H
authors.lastname: Kojima
authors.forename: N
authors.initials: N
authors.lastname: Takemura
authors.forename: T
authors.initials: T
authors.lastname: Tsuchida
authors.forename: H
authors.initials: H
authors.lastname: Tachibana
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001922:Brain Abscess / Q000175:diagnosis / Q000469:parasitology* / Q000628:therapy; D016054:DNA, Protozoan / Q000032:analysis; D004322:Drainage; D004640:Emetine / Q000008:administration & dosage / Q000627:therapeutic use; D004748:Entamoeba histolytica / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D004749:Entamoebiasis / Q000175:diagnosis* / Q000628:therapy; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007273:Injections, Intramuscular; D007441:Intubation, Gastrointestinal; D008101:Liver Abscess, Amebic / Q000150:complications; D008279:Magnetic Resonance Imaging; D008297:Male; D008581:Meningitis / Q000150:complications / Q000469:parasitology; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014057:Tomography, X-Ray Computed
chemical_list: D000913:Antibodies, Protozoan; D016054:DNA, Protozoan; D008795:Metronidazole; D004640:Emetine