title: Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.
abstract: Propoxyphene overdose is known to cause widening of the QRS complex on ECG. We report a case of a 54-year-old female who ingested approximately 100 propoxyphene hydrochloride tablets in a suicide attempt. She developed a wide complex dysrhythmia which responded to sodium bicarbonate therapy. Propoxyphene-induced wide complex dysrhythmia responsive to sodium bicarbonate therapy has not been previously reported in the literature.
authors.affiliation: New York City Poison Control Center, NY 10016.
authors.forename: C M
authors.initials: CM
authors.lastname: Stork
authors.forename: J T
authors.initials: JT
authors.lastname: Redd
authors.forename: K
authors.initials: K
authors.lastname: Fine
authors.forename: R S
authors.initials: RS
authors.lastname: Hoffman
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000506:poisoning; D001145:Arrhythmias, Cardiac / Q000097:blood / Q000139:chemically induced* / Q000188:drug therapy*; D011431:Dextropropoxyphene / Q000506:poisoning*; D004347:Drug Interactions; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D005473:Fluoxetine / Q000506:poisoning; D006801:Humans; D008875:Middle Aged; D017693:Sodium Bicarbonate / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005473:Fluoxetine; D017693:Sodium Bicarbonate; D011431:Dextropropoxyphene