title: [Elimination of N,N-dimethyltryptamine by urine].
abstract: N,N-dimethiltryptamine (DMT) in urine has been quantified on an 83-psychiatric patient sample. Sample covered patients who had sometimes been administered neuroleptic drugs as well as patients with some particular symptomatology associated to psychotic disorders such as hallucinations, delusions, perception disorders, etc. 43.3% (36 cases) evidenced an abnormally high DMT in urine (0.9-13.5 mcg/24 h). Higher values were more frequently found in both schizophrenic patients, and non-schizophrenic patients with either hallucinations, delusions, anorexia or bulimia. Most patients with DMT normal values (< 0.5 mcg/24 h) presented either mental retardation, cerebral atrophy or dysrhythmias. A very good correlation was found between urinary DMT abnormally high values, and patients' improvement after such patients had been treated with neuroleptic drugs.
authors.affiliation: Laboratorio de Psiquiatría Biológica, Buenos Aires, Argentina.
authors.forename: N
authors.initials: N
authors.lastname: Spatz
authors.forename: H
authors.initials: H
authors.lastname: Spatz
authors.forename: H L
authors.initials: HL
authors.lastname: Mesones Arroyo
authors.forename: T
authors.initials: T
authors.lastname: Rosan
authors.forename: F
authors.initials: F
authors.lastname: Brengio
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000652:urine; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy / Q000652:urine*; D008875:Middle Aged; D004130:N,N-Dimethyltryptamine / Q000652:urine*
chemical_list: D014150:Antipsychotic Agents; D015415:Biomarkers; D004130:N,N-Dimethyltryptamine
vernacular_title: Eliminación de N,N-dimetiltriptamina por la orina.