Sulfoxide reduction: organ-dependence and species variability of biotransformational sulfoxide reduction of oxyprothepine-8-sulfoxide in the cytoplasma.
Pauliková
I
I
Department of Cell and Molecular Biology of Drugs, Faculty of Pharmacy, Komensky University, Bratislava, Slovak Republic.
Helia
O
O
D000818:Animals; D001711:Biotransformation; D002682:Chinchilla; D003593:Cytoplasm / Q000378:metabolism*; D003988:Dibenzothiepins / Q000493:pharmacokinetics*; D006168:Guinea Pigs; D006801:Humans; D007231:Infant, Newborn; D051379:Mice; D008807:Mice, Inbred BALB C; D009928:Organ Specificity; D010084:Oxidation-Reduction; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D013045:Species Specificity; D013454:Sulfoxides / Q000493:pharmacokinetics*
D003988:Dibenzothiepins; D013454:Sulfoxides