title: [Intraperitoneal hyperthermic chemotherapy (IPHC), a promising treatment of peritoneal carcinomatosis].
abstract: Intraperitoneal hyperthermic chemotherapy (IPHC) appears to be a promising treatment of peritoneal carcinomatosis. This paper reports the physio-pathological background of IPHC and the various studies which have been published in the literature. It points out the heterogeneity of these series and discuss the most critical points as surgical indications, choice of the antineoplastic drugs, their doses, temperatures of the IPHC, extend of the cytoreductive surgery, morbidity and mortality. Finally, several options are proposed for those points which are not yet standardized.
authors.affiliation: Service de chirurgie digestive carcinologique, institut Gustave-Roussy, Villejuif, France.
authors.forename: B
authors.initials: B
authors.lastname: Detroz
authors.forename: D
authors.initials: D
authors.lastname: Elias
authors.forename: E
authors.initials: E
authors.lastname: Damia
authors.forename: B
authors.initials: B
authors.lastname: Debaene
authors.forename: P
authors.initials: P
authors.lastname: Rougier
authors.forename: P
authors.initials: P
authors.lastname: Lasser
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy* / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D004195:Disease Models, Animal; D004285:Dogs; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007036:Hypothermia, Induced / Q000379:methods; D007263:Infusions, Parenteral; D008937:Mitomycins / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary; D051381:Rats; D015996:Survival Rate
chemical_list: D008937:Mitomycins; D002945:Cisplatin
vernacular_title: La chimio-hyperthermie intrapéritonéale (CHIP), un traitement prometteur mais encore mal connu de la carcinose péritonéale.