title: Molecular cloning of a cDNA encoding human histidase.
abstract: We isolated overlapping cDNA clones encoding human histidase (histidine ammonia-lyase) from a human lambda gt10 library. The cDNA predicted a 657 amino acid protein of 72,651 Da. The human histadase amino acid sequence was 93% conserved with both rat and mouse histidase sequences, including four N-glycosylation consensus sites.
authors.affiliation: Department of Pediatrics, Nagoya City University Medical School, Aichi, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Suchi
authors.forename: N
authors.initials: N
authors.lastname: Harada
authors.forename: Y
authors.initials: Y
authors.lastname: Wada
authors.forename: Y
authors.initials: Y
authors.lastname: Takagi
mesh_terms: D000592:Amino Acid Metabolism, Inborn Errors / Q000235:genetics; D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D017124:Conserved Sequence; D018076:DNA, Complementary / Q000096:biosynthesis* / Q000737:chemistry; D006639:Histidine / Q000097:blood; D006638:Histidine Ammonia-Lyase / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data
chemical_list: D018076:DNA, Complementary; D006639:Histidine; D006638:Histidine Ammonia-Lyase