title: Correlation between cell-associated mannose-sensitive hemagglutination by Vibrio parahaemolyticus and adherence to a human colonic cell line Caco-2.
abstract: Cell-associated hemagglutination (cHA) activity with human erythrocytes was examined for 468 clinical and 71 environmental strains of Vibrio parahaemolyticus. Approximately 95% of the strains tested were cHA positive irrespective of source or Kanagawa phenomenon. 75% of clinical strains showed relatively strong mannose-sensitive hemagglutination (MSHA), whereas 88% of the environmental strains showed relatively weak mannose-resistant hemagglutination (MRHA). Adherence of V. parahaemolyticus to Caco-2 cells was also determined. A clear positive correlation between cell-associated MSHA and adherence to Caco-2 cells was observed.
authors.affiliation: Research Institute for Microbial Diseases, Osaka University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nagayama
authors.forename: T
authors.initials: T
authors.lastname: Oguchi
authors.forename: M
authors.initials: M
authors.lastname: Arita
authors.forename: T
authors.initials: T
authors.lastname: Honda
mesh_terms: D001422:Bacterial Adhesion; D002460:Cell Line; D003106:Colon / Q000166:cytology; D004912:Erythrocytes; D010861:Fimbriae, Bacterial / Q000648:ultrastructure; D006384:Hemagglutination / Q000187:drug effects; D006801:Humans; D008358:Mannose / Q000494:pharmacology; D014736:Vibrio parahaemolyticus / Q000502:physiology* / Q000648:ultrastructure
chemical_list: D008358:Mannose