Clinical manifestations of photosensitivity in patients with human immunodeficiency virus infection.
A number of light-induced pathologic changes in the skin of individuals with HIV infection have been reported in the dermatologic literature. The relationship between HIV and one of these more well-defined types of photosensitivity, PCT, while still uncertain seems definable and related to an infectious origin. The relationship of retrovirus infection and photosensitivities that are of idiopathic origin in HIV-infected individuals, as well as non-infected individuals, is much more conjectural. The association seems, however, to be more frequent than co-incidental, and the link probably resides in the realm of altered immune modulation. Since individuals with HIV frequently require phototherapy, such light-induced problems are likely to become more common. It is important that the dermatologist recognize these relationships.
Gregory
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DeLeo
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D002908:Chronic Disease; D017454:Dermatitis, Photoallergic / Q000150:complications; D005814:Genes, Viral; D006678:HIV / Q000235:genetics; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D017495:Hyperpigmentation / Q000150:complications; D017512:Lichenoid Eruptions / Q000150:complications; D010787:Photosensitivity Disorders / Q000150:complications*; D017119:Porphyria Cutanea Tarda / Q000150:complications; D014466:Ultraviolet Rays