title: Dystrophin-related protein in Becker muscular dystrophy.
abstract: A benign Becker muscular dystrophy (BMD) patient with a marked decrease in dystrophin exhibited remarkable expression of dystrophin-related protein (DRP) on most of the muscle cell membrane. A phenotypic Duchenne muscular dystrophy patient with a truncated form of dystrophin exhibited no DRP expression on the muscle cell membrane except for the neuromuscular junction. Increased DRP expression might compensate for a lack of dystrophin in some BMD patients.
authors.affiliation: Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University.
authors.forename: I
authors.initials: I
authors.lastname: Higuchi
authors.forename: T
authors.initials: T
authors.lastname: Niiyama
authors.forename: H
authors.initials: H
authors.lastname: Fukunaga
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Nakagawa
authors.forename: M
authors.initials: M
authors.lastname: Osame
mesh_terms: D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal / Q000276:immunology; D002462:Cell Membrane / Q000737:chemistry; D002896:Chromosomes, Human, Pair 6 / Q000235:genetics; D003598:Cytoskeletal Proteins / Q000032:analysis* / Q000235:genetics / Q000276:immunology; D016189:Dystrophin / Q000032:analysis; D005091:Exons / Q000235:genetics; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008565:Membrane Proteins; D018485:Muscle Fibers, Skeletal / Q000737:chemistry* / Q000473:pathology; D009136:Muscular Dystrophies / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D010641:Phenotype; D016133:Polymerase Chain Reaction; D015854:Up-Regulation; D049411:Utrophin
chemical_list: D000911:Antibodies, Monoclonal; D003598:Cytoskeletal Proteins; D016189:Dystrophin; D008565:Membrane Proteins; D049411:Utrophin