title: [The role of brachytherapy in the therapeutic strategy of vesico-prostatic rhabdomyosarcoma in children].
abstract: Because of its ballistic and physical characteristics, brachytherapy (BT) represents the optimal irradiation treatment in pediatric tumors, especially in prostate or bladder rhabdomyosarcoma. In a limited series of 15 children treated with BT (including three patients treated with salvage BT), 8 out of 9 patients surviving with NED benefited from conservative treatment among 12 patients treated with BT as first-line treatment. Sequelae were minimal consisting of one grade I cystitis and one asymptomatic vesical and ureteral reflux. BT allows administration of high doses to limited volumes sparing normal tissues. BT--whenever possible--represents the treatment of choice compared with external radiotherapy. Indications of BT depend on tumor accessibility and size (usually < or = 4 cm).
authors.affiliation: Service de Curiethérapie, Institut Gustave-Roussy, Villejuif.
authors.forename: C
authors.initials: C
authors.lastname: Haie-Meder
authors.forename: F
authors.initials: F
authors.lastname: Flamant
authors.forename: Y
authors.initials: Y
authors.lastname: Revillon
authors.forename: J
authors.initials: J
authors.lastname: Valayer
authors.forename: M
authors.initials: M
authors.lastname: Gruner
authors.forename: H
authors.initials: H
authors.lastname: Martelli
authors.forename: J L
authors.initials: JL
authors.lastname: Habrand
authors.forename: M J
authors.initials: MJ
authors.lastname: Terrier-Lacombe
authors.forename: A
authors.initials: A
authors.lastname: Gerbaulet
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001918:Brachytherapy / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D015653:Cystectomy; D006801:Humans; D007223:Infant; D007496:Iridium Radioisotopes / Q000627:therapeutic use; D008297:Male; D009364:Neoplasm Recurrence, Local; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012208:Rhabdomyosarcoma / Q000532:radiotherapy*; D016879:Salvage Therapy; D015996:Survival Rate; D001749:Urinary Bladder Neoplasms / Q000532:radiotherapy*
chemical_list: D007496:Iridium Radioisotopes
vernacular_title: Place de la curiethérapie dans la stratégie thérapeutique des rhabdomyosarcomes vésico-prostatiques de l'enfant.