title: [Results of adjuvant therapy with the preparation Poly-a Poly-u in patients with malignant melanoma during a 10-year observation].
abstract: During 10 years patients with malignant melanoma were followed up after radical removal of primary tumour and metastatic regional lymph nodes, the half of whom was given immunomodulation with the preparation Poly-A Poly-U in a controlled clinical trial. It was found that the performed immunomodulation exerted slight effect on the course of malignant melanoma causing later development of recurrence, less dynamic course of the disease, longer asymptomatic periods in relation to the control group. No effect of the drug administration was observed on longterm survival.
authors.affiliation: Kliniki Chemioterapii Instytutu Onkologii w Krakowie.
authors.forename: M
authors.initials: M
authors.lastname: Pawlicki
authors.forename: M
authors.initials: M
authors.lastname: Jońca
authors.forename: K
authors.initials: K
authors.lastname: Krzemieniecki
authors.forename: B
authors.initials: B
authors.lastname: Zuchowska-Vogelgesang
mesh_terms: D017024:Chemotherapy, Adjuvant; D006801:Humans; D007167:Immunotherapy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D011063:Poly A-U / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D015996:Survival Rate
chemical_list: D011063:Poly A-U
vernacular_title: Wyniki adjuwantnej terapii preparatem Poly-A Poly-U u chorych na czerniaka złośliwego w 10-letniej obserwacji.