title: Analysis of Breslow tumor thickness distribution of skin melanoma in the Italian region of Romagna, 1986-1991.
abstract: OBJECTIVE
  In southern European countries, the availability of epidemiologic data on cutaneous malignant melanoma is limited. A descriptive analysis was performed on melanoma cases diagnosed in the Italian region of Romagna (population 600,000), 1986-91.
  
  
  METHODS
  The main end point was the proportion of cases less than 1.5 mm thick by sex, age, and site.
  
  
  RESULTS
  A total of 297 incident cases was evaluated. The average annual age-standardized (World) incidence rates were 6.2 (95% CI 5.2-7.2) per 100,000 females and 4.5 (95% CI 3.6-5.3) per 100,000 males. Females presented with significantly thinner melanomas than males. The proportion of cases less than 1.5 mm thick decreased significantly with increasing age in both sexes, with the most pronounced decrease (approximately from 2/3 to 1/3) being observed above 60 years for females and above 40 for males. Comparing sexes by 10-year age groups, a significant F:M advantage in thickness distribution was found only at age 40-49 and 50-59 years. Among females under 60, melanomas of the legs and those of the trunk showed no difference in thickness distribution. In both sexes, incidence appeared to increase progressively with age. No apparent elevation in incidence rates was observed in the age groups with the highest frequency of thin melanomas.
  
  
  CONCLUSIONS
  The major implication of these data is that in public education programs specific messages should be aimed at those subgroups that show the poorest levels of self-surveillance.
authors.affiliation: Dermatology Department, Health Care District 35, Ravenna, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Stanganelli
authors.forename: A A
authors.initials: AA
authors.lastname: Raccagni
authors.forename: L
authors.initials: L
authors.lastname: Baldassari
authors.forename: D
authors.initials: D
authors.lastname: Calista
authors.forename: M
authors.initials: M
authors.lastname: Serafini
authors.forename: L
authors.initials: L
authors.lastname: Bucchi
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008545:Melanoma / Q000453:epidemiology* / Q000473:pathology*; D008875:Middle Aged; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000473:pathology*