Intramuscular ketorolac for postoperative analgesia following laparoscopic sterilisation.
The analgesic effect of intramuscular ketorolac was assessed by double blind study in forty women presenting for day-case laparoscopic sterilisation. The patients were randomly allocated to receive either ketorolac 30 mg or saline by intramuscular injection immediately following induction of general anaesthesia. There was no statistically significant difference between the groups in pain scores, opioid requirements or incidence of nausea and vomiting in the postoperative period. In view of the potential side-effects of ketorolac, and the apparent lack of efficacy when used prophylactically, the routine use of the drug in this group of patients cannot be recommended.
Shapiro
M H
MH
Department of Anaesthesia and Resuscitation, Queen Elizabeth Hospital, Adelaide, South Australia.
Duffy
B L
BL
D000328:Adult; D000698:Analgesia; D000700:Analgesics / Q000008:administration & dosage* / Q000009:adverse effects; D000701:Analgesics, Opioid / Q000008:administration & dosage; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D020910:Ketorolac; D010535:Laparoscopy / Q000009:adverse effects; D008614:Meperidine / Q000008:administration & dosage; D009325:Nausea / Q000139:chemically induced; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D010919:Placebos; D013246:Sterilization, Tubal / Q000009:adverse effects; D014046:Tolmetin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D014839:Vomiting / Q000139:chemically induced
D000700:Analgesics; D000701:Analgesics, Opioid; D010919:Placebos; D008614:Meperidine; D014046:Tolmetin; D020910:Ketorolac