title: Biochemical and physiological parameters of recovery in acute severe head injury: responses to multisensory stimulation.
abstract: We investigated the efficacy of applying a programme of multisensory stimulation to patients with severe diffuse traumatic brain injury, during their admission to a tertiary neurosurgical intensive care unit. We attempted to determine the nature and extent of any physiological or biochemical changes occurring as a result of the multisensory stimulation in the initial period of their comatose state. The findings were inconclusive with no significant treatment effect demonstrated.
authors.affiliation: Department of Psychology, Atkinson Morley's Hospital, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Johnson
authors.forename: K
authors.initials: K
authors.lastname: Roethig-Johnston
authors.forename: D
authors.initials: D
authors.lastname: Richards
mesh_terms: D000110:Acetylcholinesterase / Q000097:blood; D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000502:physiology*; D001364:Awareness / Q000502:physiology*; D001925:Brain Damage, Chronic / Q000401:mortality / Q000503:physiopathology / Q000534:rehabilitation*; D001930:Brain Injuries / Q000401:mortality / Q000503:physiopathology / Q000534:rehabilitation*; D005500:Follow-Up Studies; D005712:Galvanic Skin Response / Q000502:physiology; D015600:Glasgow Coma Scale; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000097:blood; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000097:blood*; D026741:Physical Therapy Modalities / Q000379:methods*; D012024:Reflex, Oculocardiac / Q000502:physiology; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology; D012683:Sensory Deprivation / Q000502:physiology*; D015996:Survival Rate
chemical_list: D018377:Neurotransmitter Agents; D008734:Methoxyhydroxyphenylglycol; D000110:Acetylcholinesterase