Variation in glucose tolerance with ambient temperature.
Ambient temperature may affect venous glucose concentration after glucose tolerance tests. We analysed 1030 standardised 75 g tests. Although mean fasting values did not differ, post-load values did: adjusted mean 2 h glucose concentration was 1.03 mmol/L lower at lower (5-14 degrees C) than at higher (25-31 degrees C) temperatures (p < 0.001). The occurrence of abnormal glucose tolerance doubled on warmer days. The diagnostic accuracy of the glucose tolerance test showed clinically significant temperature-associated variation. These variations, if confirmed, call for temperature standardisation during glucose tolerance testing and/or alternative strategies for use when standardisation is not feasible.
Schmidt
M I
MI
Department of Social Medicine, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Matos
M C
MC
Branchtein
L
L
Reichelt
A J
AJ
Mengue
S S
SS
Iochida
L C
LC
Duncan
B B
BB
D000328:Adult; D004781:Environmental Exposure; D005260:Female; D005951:Glucose Tolerance Test / Q000592:standards; D006801:Humans; D008875:Middle Aged; D013696:Temperature