[Merkel cell carcinoma of the face. Histology, clinical course and therapy in six cases].
Six patients suffering from Merkel cell carcinoma of the face are described. A reliable confirmation and differential diagnosis of Merkel cell carcinoma have become possible with the aid of immunohistochemistry. There is a poor prognosis for patients affected by this tumour. Three out of the six cases described died within two years, two of them with distant metastases, one with a widespread local recurrence. Optimal treatment of Merkel cell carcinoma consists in early radical resection, perhaps combined with radiotherapy.
Hellner
D
D
Mund-, Kiefer-, Gesichtschirurgie, Nordwestdeutsche Kieferklinik, Universitätskrankenhaus Eppendorf, Hamburg, Deutschland.
Günzl
H J
HJ
Friedrich
R
R
Schmelzle
R
R
D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000032:analysis; D015266:Carcinoma, Merkel Cell / Q000473:pathology* / Q000503:physiopathology / Q000532:radiotherapy / Q000601:surgery; D005153:Facial Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000532:radiotherapy / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009364:Neoplasm Recurrence, Local; D011379:Prognosis
D014408:Biomarkers, Tumor
Das Merkelzellkarzinom im Gesichtsbereich. Histologie, klinischer Verlauf und Therapie bei 6 Fällen.