title: Intra- and extra-uterine development of neonatal 3-channel Lissajous' trajectory of auditory brainstem evoked potentials.
abstract: This study compared intra- and extra-uterine maturation of the auditory pathway, using auditory brainstem evoked potentials (ABEPs), recorded with three orthogonal differential electrode configurations. From the three records of each subject, 3-channel Lissajous' trajectories (3CLTs) were derived and analyzed. 107 newborns were compared at the same gestational and post-conceptional (gestational+postnatal) age, from 29 weeks (wks) up to 43 wks. In addition, we explored the effects and neurophysiological consequences of early exposure to extra-uterine life, on the peripheral and central portions of the auditory pathway. Our findings indicate that exposure of premature infants to the extra-uterine environment is associated with advanced peripheral development, but slower central conduction compared to intra-uterine development.
authors.affiliation: Evoked Potentials Laboratory, Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: H
authors.initials: H
authors.lastname: Hafner
authors.forename: H
authors.initials: H
authors.lastname: Pratt
authors.forename: S
authors.initials: S
authors.lastname: Blazer
authors.forename: P
authors.initials: P
authors.lastname: Sujov
mesh_terms: D000704:Analysis of Variance; D004566:Electrodes; D004594:Electrophysiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn / Q000254:growth & development* / Q000502:physiology; D007234:Infant, Premature / Q000254:growth & development* / Q000502:physiology; D007557:Israel