title: Transcriptional activation. Switched-on chromatin.
abstract: A large 'SWI/SNF' general activator complex serves as a molecular machine to help a wide range of transcription factors overcome the specific repressive effects of chromatin.
authors.affiliation: Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892.
authors.forename: A P
authors.initials: AP
authors.lastname: Wolffe
mesh_terms: D000818:Animals; D001665:Binding Sites; D002843:Chromatin / Q000235:genetics*; D004247:DNA / Q000378:metabolism; D005812:Genes, Switch; D006657:Histones / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008958:Models, Molecular; D015533:Transcriptional Activation
chemical_list: D002843:Chromatin; D006657:Histones; D004247:DNA