title: Chronic actinic dermatitis: a clinical and photobiological study in 6 Japanese patients.
abstract: Chronic actinic dermatitis (CAD) has distinct clinical features different from polymorphous light eruption (PLE). In order to clarify the difference between CAD and PLE, not only in clinical histories and findings but also in photobiological and histopathological reactions to phototests, we investigated 6 Japanese patients with CAD and performed provocative phototests which are our standardized methods in diagnosing PLE. On provocative phototests in CAD, pruritic papules were reproduced with smaller doses of UVB, at longer hours after irradiation (48-72 h) and they lasted for more days than in patients with PLE. Our study demonstrated that although milder cases of CAD and severe cases of PLE could not be distinguished clearly based on photobiological reactions alone, typical cases of CAD showed completely different provocative phototest results from those of PLE.
authors.affiliation: Department of Dermatology, School of Medicine, Tokyo Medical and Dental University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kurumaji
authors.forename: C
authors.initials: C
authors.lastname: Miyamoto
authors.forename: S
authors.initials: S
authors.lastname: Fukuro
authors.forename: S
authors.initials: S
authors.lastname: Kondo
authors.forename: C
authors.initials: C
authors.lastname: Keong
authors.forename: K
authors.initials: K
authors.lastname: Nishioka
authors.forename: Y
authors.initials: Y
authors.lastname: Satoh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D012867:Skin / Q000473:pathology / Q000528:radiation effects; D014466:Ultraviolet Rays / Q000009:adverse effects