title: Effect of immobilization stress on tumor growth in mice.
abstract: The effect of immobilization stress applied daily for 2 h on the development of MF-RSV tumor graft in mice and on survival of the hosts was studied. While a single acute stress applied to mice simultaneously with a transfer of MF-RSV cells stimulated antitumor defense, chronic stress applied both before and/or after tumor cell implantation accelerated the death of recipients. The shortest survival time was found in mice which were stressed for 3 weeks before implantation and on, until their death. Heat shock applied to MF-RSV tumor cells before implantation significantly reduced their growth ability in the hosts.
authors.affiliation: Department of Immunology, Polish Academy of Sciences, Kraków.
authors.forename: B
authors.initials: B
authors.lastname: Mazur-Kolecka
authors.forename: O
authors.initials: O
authors.lastname: Machala
authors.forename: A
authors.initials: A
authors.lastname: Skowron-Cendrzak
authors.forename: M
authors.initials: M
authors.lastname: Kubera
authors.forename: M
authors.initials: M
authors.lastname: Bubak-Satora
authors.forename: A
authors.initials: A
authors.lastname: Basta-Kaim
authors.forename: A
authors.initials: A
authors.lastname: Roman
mesh_terms: D000818:Animals; D002455:Cell Division / Q000502:physiology; D002470:Cell Survival / Q000502:physiology; D006358:Hot Temperature; D007103:Immobilization; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000473:pathology*; D012769:Shock / Q000503:physiopathology; D013312:Stress, Physiological / Q000209:etiology / Q000503:physiopathology*; D014407:Tumor Cells, Cultured