title: Propofol for pulsed dye laser treatments in paediatric outpatients.
abstract: Pulsed dye laser is a new treatment for port-wine stains, congenital lesions in the cutaneous vascular plexus. We report our anesthetic experience with paediatric outpatients treated in the dermatology clinic. From April to November 1993, 48 ASA 1 children were anaesthetised for a total of 105 consecutive laser treatments. The youngest was eight months old, the oldest was 12 yrs old and most of the sessions (43%) were done for children aged from two to four years. Each received acetaminophen (10 mg.kg-1 p.o.) before treatment. A propofol infusion was chosen for anaesthesia to achieve early discharge and to reduce the incidence of postoperative emesis. The infusion was adjusted to maintain blood pressure within 20% of baseline and to keep the child immobile. The dose was progressively reduced during the procedure from 400 micrograms.kg-1.min-1 to 100 micrograms.kg-1.min-1. Fentanyl (2 micrograms.kg-1 i.v.) was added for analgesia. Respiration was spontaneous through a nasopharyngeal airway (air in oxygen 40%). Anaesthesia proceeded uneventfully in all cases and lasted for 15-30 min (63% of treatments), 30-45 min (28%) or 45-60 min (9%) according to the size of the lesion. The mean stay in the recovery room was 25.1 min and none of the patients experienced emesis. Our experience shows that general anaesthesia with propofol supplemented with fentanyl offers a rapid onset and awakening, a painless treatment and an immobile child. It is a safe solution to alleviate pain from repeated painful procedures even in small children under two years of age.
authors.affiliation: Department of Anaesthesia, Sainte-Justine Hospital, Montreal, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Vischoff
authors.forename: J
authors.initials: J
authors.lastname: Charest
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage; D000762:Anesthesia Recovery Period; D000771:Anesthesia, Intravenous; D002648:Child; D002675:Child, Preschool; D005148:Facial Dermatoses / Q000601:surgery*; D005283:Fentanyl / Q000008:administration & dosage; D006222:Hamartoma / Q000601:surgery*; D006801:Humans; D007223:Infant; D017075:Laser Coagulation; D008874:Midazolam / Q000008:administration & dosage; D010149:Postoperative Pain / Q000517:prevention & control; D015742:Propofol / Q000008:administration & dosage; D011595:Psychomotor Agitation / Q000209:etiology
chemical_list: D000082:Acetaminophen; D008874:Midazolam; D005283:Fentanyl; D015742:Propofol