title: Late recurrence of Wegener's granulomatosis presenting as solitary upper lobe pulmonary mass.
abstract: Recurrent Wegener's granulomatosis (WG) was diagnosed in a 40 year old man presenting with a solitary mass in the right lung apex and with possible lymph node enlargement in the anterior mediastinum, resembling malignancy. Eight years previously, a first episode of WG involving the upper airways and kidneys, but not the lungs, had been successfully treated with prednisolone and cyclophosphamide, which could be stopped after 2 yrs. The antineutrophil cytoplasmic antibody titres (anti-protease 3), which had been very high during the first disease episode, failed to predict the recurrence.
authors.affiliation: Dept of Pulmonary Diseases, Intensive and Respiratory Care, Groningen University Hospital, The Netherlands.
authors.forename: T S
authors.initials: TS
authors.lastname: van der Werf
authors.forename: C A
authors.initials: CA
authors.lastname: Stegeman
authors.forename: K J
authors.initials: KJ
authors.lastname: Meuzelaar
authors.forename: W
authors.initials: W
authors.lastname: Timens
mesh_terms: D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000032:analysis; D014890:Granulomatosis with Polyangiitis / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D011859:Radiography; D012008:Recurrence
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies