title: Epidemiology of cryptosporidiosis among persons with acquired immunodeficiency syndrome in Los Angeles County.
abstract: To determine the occurrence and factors associated with Cryptosporidium among persons with acquired immunodeficiency syndrome (AIDS) in Los Angeles County, data were analyzed from the AIDS surveillance registry for the 10-year period 1983-1992. Among 16,953 persons with AIDS, a total of 638 (3.8%) cryptosporidiosis cases were reported during the study period. The prevalence of cryptosporidiosis was higher in persons whose suspected human immunodeficiency virus (HIV) exposure category was through sexual contact (3.9%) than among persons in other HIV exposure categories (2.6%; P < 0.01) and in immigrants from Mexico (5.2%) than in American born patients (3.8%; P < 0.01). Blacks (2.7%) were less likely than whites (4.1%) and Latinos (4.2%) to be reported with cryptosporidiosis (P < 0.001). A temporal trend was observed from 1983 to 1986 when the prevalence decreased from 6.7% to 3.6% (P < 0.001, by chi-square test for trend). After controlling for confounding variables by stratified analysis, persons whose HIV exposure was sexual (adjusted odds ratio [OR] = 1.7, 95% confidence interval [CI] 1.3, 2.4, P < 0.01) and immigrants from Mexico (adjusted OR = 1.6, 95% CI 1.2, 2.1, P < 0.01) were more likely to have cryptosporidiosis. The negative association with black race remained significant (adjusted OR = 0.7, 95% CI 0.57, 0.96, P = 0.02). The prevalence of cryptosporidiosis decreased with age in gay and bisexual males (Mantel-Haenszel test for trend, P < 0.01) but not among female and heterosexual male cases.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: HIV Epidemiology Program, Los Angeles County Department of Health Services, California.
authors.forename: F J
authors.initials: FJ
authors.lastname: Sorvillo
authors.forename: L E
authors.initials: LE
authors.lastname: Lieb
authors.forename: P R
authors.initials: PR
authors.lastname: Kerndt
authors.forename: L R
authors.initials: LR
authors.lastname: Ash
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000635:transmission; D000293:Adolescent; D000328:Adult; D001741:Black or African American; D000367:Age Factors; D001727:Bisexuality; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D003457:Cryptosporidiosis / Q000150:complications / Q000453:epidemiology* / Q000635:transmission; D005260:Female; D006630:Hispanic or Latino; D018451:Homosexuality, Male; D006801:Humans; D015141:Los Angeles / Q000453:epidemiology; D008297:Male; D008800:Mexico / Q000208:ethnology; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012042:Registries; D012737:Sex Factors; D012725:Sexual Behavior; D044465:White People