title: Rapid-rate transcranial magnetic stimulation and hemispheric language dominance: usefulness and safety in epilepsy.
abstract: We performed rapid-rate transcranial magnetic stimulation (r-TMS) in 14 epileptic patients, using a coil centered over nine different positions on each side of the scalp and while the subjects counted aloud. We obtained lateralized speech arrest, concordant with the site of manual preference, in only seven patients. There was transitory homonymous hemianopia (one patient), brief jerking of one arm (two patients), and affective (crying) reaction (three patients) after the end of a train of stimuli. In our experience, r-TMS is not as sensitive as previously reported for determination of hemispheric language dominance and may have undesirable side effects.
authors.affiliation: Department of Neurology, University of Bologna, Bellaria Hospital, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Michelucci
authors.forename: F
authors.initials: F
authors.lastname: Valzania
authors.forename: D
authors.initials: D
authors.lastname: Passarelli
authors.forename: M
authors.initials: M
authors.lastname: Santangelo
authors.forename: R
authors.initials: R
authors.lastname: Rizzi
authors.forename: A M
authors.initials: AM
authors.lastname: Buzzi
authors.forename: A
authors.initials: A
authors.lastname: Tempestini
authors.forename: C A
authors.initials: CA
authors.lastname: Tassinari
mesh_terms: D000328:Adult; D001931:Brain Mapping; D004292:Dominance, Cerebral; D055590:Electromagnetic Phenomena; D004827:Epilepsy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D013060:Speech