Cross-reactivity of monovalent and polyvalent Trimeresurus antivenoms with venoms from various species of Trimeresurus (lance-headed pit viper) snake.
Trimeresurus bite is a serious medical problem in Asia. However, at present only a few monospecific Trimeresurus antivenoms are available. Investigation of the cross-neutralization capacity of three Trimeresurus antivenoms indicates that the antivenoms exhibit broad cross-reactivity. A polyvalent Trimeresurus antivenom was also found to be effective in neutralization of the haemorrhagic, necrotizing and thrombin-like activities of heterologous Trimeresurus venoms.
Tan
N H
NH
Department of Biochemistry, University of Malaya, Kuala Lumpur, Malaysia.
Choy
S K
SK
Chin
K M
KM
Ponnudurai
G
G
D000818:Animals; D000997:Antivenins / Q000276:immunology*; D003429:Cross Reactions; D003435:Crotalid Venoms / Q000276:immunology*; D013045:Species Specificity; D017841:Trimeresurus / Q000276:immunology*
D000997:Antivenins; D003435:Crotalid Venoms; C029748:Trimeresurus venoms