title: Variation in glucose tolerance with ambient temperature.
abstract: Ambient temperature may affect venous glucose concentration after glucose tolerance tests. We analysed 1030 standardised 75 g tests. Although mean fasting values did not differ, post-load values did: adjusted mean 2 h glucose concentration was 1.03 mmol/L lower at lower (5-14 degrees C) than at higher (25-31 degrees C) temperatures (p < 0.001). The occurrence of abnormal glucose tolerance doubled on warmer days. The diagnostic accuracy of the glucose tolerance test showed clinically significant temperature-associated variation. These variations, if confirmed, call for temperature standardisation during glucose tolerance testing and/or alternative strategies for use when standardisation is not feasible.
authors.affiliation: Department of Social Medicine, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: M I
authors.initials: MI
authors.lastname: Schmidt
authors.forename: M C
authors.initials: MC
authors.lastname: Matos
authors.forename: L
authors.initials: L
authors.lastname: Branchtein
authors.forename: A J
authors.initials: AJ
authors.lastname: Reichelt
authors.forename: S S
authors.initials: SS
authors.lastname: Mengue
authors.forename: L C
authors.initials: LC
authors.lastname: Iochida
authors.forename: B B
authors.initials: BB
authors.lastname: Duncan
mesh_terms: D000328:Adult; D004781:Environmental Exposure; D005260:Female; D005951:Glucose Tolerance Test / Q000592:standards; D006801:Humans; D008875:Middle Aged; D013696:Temperature