title: Pregnancy rates after operative endoscopic treatment of total (neosalpingostomy) or near total (salpingostomy) distal tubal occlusion.
abstract: OBJECTIVE
  To determine the efficacy of the endoscopic treatment of complete distal tubal occlusion or moderate to severe tubal phimosis and to analyze outcome using contemporary statistical methodologies.
  
  
  METHODS
  Prospective cohort analysis.
  
  
  METHODS
  Tertiary-care institution.
  
  
  METHODS
  One hundred thirteen consecutive patients undergoing a neosalpingostomy or salpingostomy.
  
  
  METHODS
  KTP/532 laser (Laserscope, Santa Clara, CA) laparoscopy. Additional infertility factors were treated postoperatively.
  
  
  METHODS
  Crude pregnancy rate (PR), monthly fecundity rate, monthly probability of pregnancy, cure rate, and cumulative PRs. Outcome was compared on the basis of the surgical procedure performed. The impact of endometriosis as well as other fertility factors was analyzed.
  
  
  RESULTS
  Twenty-three patients conceived yielding a crude PR of 20.4%, a monthly fecundity rate of 2.6%, a monthly probability of pregnancy of 6.4%, and a cure rate of 52.4%. There were six ectopic pregnancies (5.3%). A significant difference was found among the cumulative pregnancy curves. The cumulative pregnancy curve for unilateral salpingostomy differed significantly from that of unilateral neosalpingostomy. Patients with endometriosis and no other infertility factors had a significantly better cumulative pregnancy curve compared with patients without endometriosis or other factors as well as compared with patients with no endometriosis but with other infertility factors. Patients undergoing bilateral neosalpingostomy had a cure rate of 9.0% whereas patients undergoing bilateral salpingostomy had a cure rate of 34.2%.
  
  
  CONCLUSIONS
  Operative endoscopy yields PRs that are comparable to those reported in the literature for laparotomy. The presence of complete bilateral distal tubal occlusion has a negative impact on outcome.
authors.affiliation: Department of Gynecology and Obstetrics, Henry Ford Hospital, Detroit, Michigan.
authors.forename: A M
authors.initials: AM
authors.lastname: Dlugi
authors.forename: S
authors.initials: S
authors.lastname: Reddy
authors.forename: W A
authors.initials: WA
authors.lastname: Saleh
authors.forename: M S
authors.initials: MS
authors.lastname: Mersol-Barg
authors.forename: G
authors.initials: G
authors.lastname: Jacobsen
mesh_terms: D000328:Adult; D015331:Cohort Studies; D004715:Endometriosis / Q000150:complications; D005184:Fallopian Tube Diseases / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications / Q000601:surgery*; D053685:Laser Therapy; D008875:Middle Aged; D011247:Pregnancy; D011446:Prospective Studies; D012086:Reoperation; D012489:Salpingostomy; D000267:Tissue Adhesions