title: Tuberculous pericardial effusion associated with HIV infection: a sign of disseminated disease.
abstract: OBJECTIVE
  To determine whether tuberculous pericardial effusion is associated with HIV infection.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Harare, Zimbabwe.
  
  
  METHODS
  61 consecutive patients presenting with tuberculous pericarditis over an 18 month period.
  
  
  RESULTS
  Tuberculous pericarditis was significantly associated with HIV seropositivity (odds ratio [OR] 2.46, 95% confidence interval [CI] 1.4-4.3, P = 0.001). The combination of tuberculous pericarditis and tuberculosis at another clinically obvious site (disseminated disease) was more common than pericarditis alone, and was significantly associated with HIV seropositivity (OR 6.1, CI 1.5-25, P = 0.007). Patients with disseminated disease were usually in CDC stage IV prior to the diagnosis of their tuberculosis.
authors.affiliation: Department of Medicine, University of Zimbabwe, Harare.
authors.forename: A L
authors.initials: AL
authors.lastname: Pozniak
authors.forename: J
authors.initials: J
authors.lastname: Weinberg
authors.forename: M
authors.initials: M
authors.lastname: Mahari
authors.forename: P
authors.initials: P
authors.lastname: Neill
authors.forename: S
authors.initials: S
authors.lastname: Houston
authors.forename: A
authors.initials: A
authors.lastname: Latif
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010495:Pericarditis, Tuberculous / Q000150:complications*; D012189:Retrospective Studies; D014376:Tuberculosis / Q000150:complications; D014388:Tuberculosis, Lymph Node / Q000150:complications; D014396:Tuberculosis, Pleural / Q000150:complications; D014397:Tuberculosis, Pulmonary / Q000150:complications