title: Serum Cohn fraction IV-1 supports the growth of Giardia lamblia in vitro.
abstract: Bovine serum Cohn fractions were substituted for whole bovine serum in TYI-S-33 medium. Only fraction IV-1 supported attachment, cysteine uptake, and growth of Giardia lamblia. Among the mammalian sources tested, only goat and horse fractions showed activities comparable to that of the bovine fraction. Agglutinating immunoglobulins were identified as deleterious agents in human, rat, rabbit, and dog fractions.
authors.affiliation: Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.
authors.forename: H D
authors.initials: HD
authors.lastname: Lujan
authors.forename: L G
authors.initials: LG
authors.lastname: Byrd
authors.forename: M R
authors.initials: MR
authors.lastname: Mowatt
authors.forename: T E
authors.initials: TE
authors.lastname: Nash
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000494:pharmacology*; D002417:Cattle; D003470:Culture Media; D016829:Giardia lamblia / Q000254:growth & development*; D006801:Humans
chemical_list: D001798:Blood Proteins; C032309:Cohn fraction IV; D003470:Culture Media