Electroencephalographic and autonomic predictors of relapse in alcohol-dependent patients.
Measures of electroencephalographic and autonomic activity were recorded from 17 alcohol-dependent patients (after 7-10 and 14-17 days of abstinence) and 14 age-matched non-drug-dependent controls (after comparable intervals). The alcohol-dependent group was divided into subgroups of abstinence-prone or relapse-prone patients, based on their 3-month posttreatment outcome. Data analyses revealed that relapse-prone patients evidenced more electroencephalographic beta-activity at the vertex lead, and a larger amplitude carotid pulse than abstinence-prone patients and controls. The implications of these preliminary findings for relapse prediction and typological development are discussed.
Bauer
L O
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Department of Psychiatry, University of Connecticut School of Medicine, Farmington.
D000328:Adult; D000437:Alcoholism / Q000503:physiopathology / Q000534:rehabilitation*; D001143:Arousal / Q000187:drug effects* / Q000502:physiology; D001341:Autonomic Nervous System / Q000187:drug effects* / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D004569:Electroencephalography / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D012008:Recurrence; D012815:Signal Processing, Computer-Assisted