title: Cortical porosis under plates. Reaction to unloading or to necrosis?
abstract: Cortical porosis under plates used for the fixation of fractures is often attributed to the interference of the plates with cortical perfusion, resulting in necrosis, which in turn induces remodeling. To our knowledge, no histomorphometric studies have been published that demonstrate the correlation between cortical necrosis and porosis. The objective of this study was to test the hypothesis that cortical necrosis is related to changes associated with porosis. Standard and railed plates were applied to intact femora in ten dogs. Histomorphometric studies done at eight and twenty-four weeks after insertion of the plate failed to show a significant positive correlation between necrosis and porosis irrespective of the type of plate used. Porosis was always greater in the inner cortical sector, where no increased necrosis was noted, than in the outer cortical sector, where necrosis was present.
authors.affiliation: University of Ottawa, Ottawa General Hospital, Ontario, Canada.
authors.forename: H K
authors.initials: HK
authors.lastname: Uhthoff
authors.forename: D
authors.initials: D
authors.lastname: Boisvert
authors.forename: M
authors.initials: M
authors.lastname: Finnegan
mesh_terms: D000818:Animals; D001860:Bone Plates / Q000009:adverse effects*; D004285:Dogs; D004867:Equipment Design; D005269:Femur / Q000098:blood supply / Q000473:pathology*; D010020:Osteonecrosis / Q000209:etiology / Q000473:pathology*; D016062:Porosity; D012039:Regional Blood Flow / Q000502:physiology; D013193:Stainless Steel; D013997:Time Factors
chemical_list: D013193:Stainless Steel