title: [The effect of water immersion on humoral and urinary parameters in healthy persons and in patients with liver cirrhosis].
abstract: The authors subjected 10 healthy subjects and 13 patients inflicted by liver cirrhosis in the stage of vascular decompensation (ascites and/or oedemas) to water immersion (WI). The group of healthy subjects responded during WI by a significant increase of diuresis and sodium diuresis at its maximum in the third hour, which was accompanied by a decrease of plasma aldosterone (PA) and a decrease of atrial natriuretic factor (ANF) and digoxin-like activity (DLA). The decrease of plasma vasopressin (PAVP) was not statistically significant. In patients with liver cirrhosis a significant increase of diuresis and sodium diuresis took place, whilst the response was significant already in the first hour of WI. Only 3 non-respondents were among the ill patients. In the group of liver cirrhotics also a significant decrease of AVP, PA, and an increase of ANF and DLA were recorded, the response of humoral factors was not significant due to great variability. A long term administration of diuretics (Spirolakton+Furosemid) did not decrease the serum K in ill patients. Hence, WI by means of supervention of volume expansion evokes an increase of diuresis and natriuresis in both healthy and ill subjects, the latter with decompensated liver cirrhosis which is associated with a controversial reaction of sodium diuresis and sodium retention factors. It is possible to use it as a supplementary method in the therapy of oedemas due to liver cirrhosis besides diuretic therapy. (Tab. 2, Fig. 3, Ref. 22.)
authors.affiliation: II. interná klinika FN v Kosiciach, Slovakia.
authors.forename: I
authors.initials: I
authors.lastname: Lazúrová
authors.forename: B
authors.initials: B
authors.lastname: Lichardus
authors.forename: J
authors.initials: J
authors.lastname: Luczy
authors.forename: I
authors.initials: I
authors.lastname: Rosochová
authors.forename: D
authors.initials: D
authors.lastname: Trejbal
authors.forename: Y
authors.initials: Y
authors.lastname: Machánová
authors.forename: T
authors.initials: T
authors.lastname: Hildebrand
authors.forename: E
authors.initials: E
authors.lastname: Fedorová
authors.forename: J
authors.initials: J
authors.lastname: Murár
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood; D001127:Arginine Vasopressin / Q000097:blood; D009320:Atrial Natriuretic Factor / Q000097:blood; D001798:Blood Proteins / Q000032:analysis; D002298:Cardenolides; D004077:Digoxin; D004231:Diuresis; D006801:Humans; D007101:Immersion; D008103:Liver Cirrhosis / Q000097:blood / Q000503:physiopathology*; D012503:Saponins
chemical_list: D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D001127:Arginine Vasopressin; D000450:Aldosterone; D004077:Digoxin; D009320:Atrial Natriuretic Factor
vernacular_title: Vplyv vodnej imerzie na humorálne a mocové parametre u zdravých osôb a chorých s cirhózou pecene.