Heparin-induced thrombocytopenia and thrombosis: a case study and clinical overview.
OBJECTIVE
To describe the mechanisms and nursing care associated with heparin-induced thrombocytopenia and thrombosis (HITT).


METHODS
Published books and journal articles as well as clinical experience.


RESULTS
HITT is an immune reaction that occurs in 1%-10% of individuals receiving heparin therapy. Characterized by a sudden drop in platelets, it can result in life-threatening hemorrhage and thrombus-related events.


CONCLUSIONS
Heparin commonly is used in many oncology treatment settings. Awareness of this potentially serious complication and knowledge of its treatment is critical to safe administration.


CONCLUSIONS
Astute assessment skills are the key to diagnosis and treatment of HITT.
Lapka
D M
DM
Division of Surgical Oncology, University of Illinois, Chicago Specialized Cancer Center.
Wild
L D
LD
Barbour
L A
LA
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D010347:Patient Care Planning; D013921:Thrombocytopenia / Q000097:blood / Q000139:chemically induced* / Q000276:immunology / Q000628:therapy; D013927:Thrombosis / Q000097:blood / Q000139:chemically induced* / Q000276:immunology / Q000628:therapy
D000925:Anticoagulants; D006493:Heparin