Structure-activity relationship studies of CNS agents, XV: N-[omega-(4-aryl-1-piperazinyl)alkyl]-2-oxo-1,2,3,4-tetrahydroquinoline s and -4-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indoles: new, highly potent 5-HT1A ligands.
Mokrosz
J L
JL
Department of Medicinal Chemistry, Polish Academy of Sciences, Cracow.
Duszyńska
B
B
Paluchowska
M H
MH
D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D066298:In Vitro Techniques; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D010879:Piperazines / Q000138:chemical synthesis* / Q000494:pharmacology; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D011985:Receptors, Serotonin / Q000187:drug effects*; D018490:Serotonin Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D007211:Indoles; D010879:Piperazines; D011804:Quinolines; D011985:Receptors, Serotonin; D018490:Serotonin Agents