Gene regulation. Insulating chromatin.
"Insulator elements" have been identified that define the limits of transcriptionally active chromatin domains, protecting them against the repressive influence of neighboring heterochromatin.
Wolffe
A P
AP
Laboratory of Molecular Embryology, NICHHD, NIH, Bethesda, Maryland 20892.
D000818:Animals; D002467:Cell Nucleus / Q000502:physiology / Q000648:ultrastructure; D002843:Chromatin / Q000502:physiology / Q000648:ultrastructure*; D004330:Drosophila / Q000235:genetics; D005127:Eye Color / Q000235:genetics; D006360:Heat-Shock Proteins / Q000235:genetics; D006570:Heterochromatin / Q000502:physiology / Q000648:ultrastructure; D008961:Models, Structural; D012441:Saccharomyces cerevisiae / Q000235:genetics; D014158:Transcription, Genetic
D002843:Chromatin; D006360:Heat-Shock Proteins; D006570:Heterochromatin