title: Intake of a cohort study of urban factory workers in northwest Tanzania. Risk factors for HIV-1 infection.
abstract: A cohort study has been started of urban factory workers and their spouses in Tanzania, in order to 1) identify risk factors for HIV-1 seroconversion, and 2) document changes over time in risk behaviour, in particular condom use and partner change, and determine whether these are associated with a reduced incidence of HIV-1 and other sexually transmitted diseases. We report findings at intake from October 1991 to March 1992. Study participants were interviewed, examined, and screened for HIV-1 and syphilis. HIV-1 prevalence was 91/926 (10%) in males and 36/217 (17%) in females. Statistically significant risk factors for HIV-1 infection in males were age group, region of birth, not being married for more than 5 years, being uncircumcised, having had a genital ulcer in the past four months, and having received injections from medical staff in the past four months. HIV-1 incidence in this group is expected to be between 1% and 2% per year. It is concluded that a longitudinal study is needed to assess the importance of partner change. This cohort appears to be suitable for such a study as HIV-1 incidence is expected to be fairly high, HIV-1 prevalence and risk factors are comparable to those of the general population and cooperation of the factory workers is good.
authors.affiliation: National Institute for Medical Research, Mwanza, Tanzania.
authors.forename: L R
authors.initials: LR
authors.lastname: Barongo
authors.forename: M W
authors.initials: MW
authors.lastname: Borgdorff
authors.forename: J N
authors.initials: JN
authors.lastname: Newell
authors.forename: K P
authors.initials: KP
authors.lastname: Senkoro
authors.forename: A H
authors.initials: AH
authors.lastname: Klokke
authors.forename: J
authors.initials: J
authors.lastname: Changalucha
authors.forename: W
authors.initials: W
authors.lastname: Deville
authors.forename: J P
authors.initials: JP
authors.lastname: Velema
authors.forename: R A
authors.initials: RA
authors.lastname: Coutinho
authors.forename: R M
authors.initials: RM
authors.lastname: Gabone
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012749:Sexually Transmitted Diseases / Q000453:epidemiology; D013587:Syphilis / Q000453:epidemiology; D013636:Tanzania / Q000453:epidemiology; D014505:Urban Population; D017132:Workplace