title: [Sodium valproate--still a current antiepileptic agent?].
abstract: In Switzerland valproate is in use as an anticonvulsant drug since 25 years. On this occasion we present a synopsis of the state of knowledge about its mechanism of action, pharmacokinetics, clinical efficacy, side effects, drug interactions, and administration with respect to special clinical situations.
authors.affiliation: Abteilung für Elektroenzephalographie und Anfallsambulanz, Kantonsspital Basel.
authors.forename: G
authors.initials: G
authors.lastname: Scollo-Lavizzari
authors.forename: D
authors.initials: D
authors.lastname: Proeckl
mesh_terms: D000375:Aging; D004347:Drug Interactions; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000187:drug effects; D011247:Pregnancy / Q000187:drug effects; D014635:Valproic Acid / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D005680:gamma-Aminobutyric Acid; D014635:Valproic Acid
vernacular_title: Natriumvalproat--ein noch aktuelles Antiepileptikum?