The organisation of the multigene family which encodes the major cell surface protein, pMGA, of Mycoplasma gallisepticum.
The genome of the avian pathogen Mycoplasma gallisepticum contains a number of related genes for putative adhesion molecules (pMGA). Cloning and sequence analysis of several pMGA genes suggested that all of them might be transcriptionally and translationally functional. Analysis of the gene sequence encoding the sole pMGA variant expressed in vitro in the S6 strain (pMGA1.1) revealed no unambiguous feature that could account for its unique expression. It is estimated that the pMGA gene family may contain up to 50 members, and its possible role is discussed herein.
Markham
P F
PF
Department of Veterinary Science, University of Melbourne, Parkville, Australia.
Glew
M D
MD
Sykes
J E
JE
Bowden
T R
TR
Pollocks
T D
TD
Browning
G F
GF
Whithear
K G
KG
Walker
I D
ID
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D015139:Blotting, Southern; D003001:Cloning, Molecular; D017124:Conserved Sequence; D004269:DNA, Bacterial / Q000737:chemistry / Q000378:metabolism; D015870:Gene Expression; D005798:Genes, Bacterial; D014644:Genetic Variation; D006388:Hemagglutinins / Q000235:genetics; D007438:Introns; D008969:Molecular Sequence Data; D005810:Multigene Family; D009174:Mycoplasma / Q000235:genetics* / Q000378:metabolism; D015183:Restriction Mapping; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D006388:Hemagglutinins; C079720:M9 protein, Mycoplasma gallisepticum