title: Generalized convulsive status epilepticus: causes, therapy, and outcome in 346 patients.
abstract: We report data from 346 admissions for generalized tonic-clonic convulsive status epilepticus (GC-SE); 68% had had epilepsy previously. Outcome was determined by underlying cause, SE duration of > 4 h, the presence of more than one medical complication, and the quality of therapy and management. Clonazepam (CZP), diazepam (DZP), and phenytoin (PHT) were most frequently used for treatment.
authors.affiliation: Dr. Hans Berger Clinic, Breda, The Netherlands.
authors.forename: F B
authors.initials: FB
authors.lastname: Scholtes
authors.forename: W O
authors.initials: WO
authors.lastname: Renier
authors.forename: H
authors.initials: H
authors.lastname: Meinardi
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use*; D002998:Clonazepam / Q000627:therapeutic use; D003975:Diazepam / Q000627:therapeutic use; D004363:Drug Utilization; D004829:Epilepsy, Generalized / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D010672:Phenytoin / Q000627:therapeutic use; D015995:Prevalence; D013226:Status Epilepticus / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D002998:Clonazepam; D010672:Phenytoin; D003975:Diazepam