Developmental timers. How do embryonic cells measure time?
The differentiation of oligodendrocyte precursor cells runs to a schedule that is controlled by an intrinsic timer. Recent evidence raises the possibility that the activity of a transcription factor may be central to timer function.
Ffrench-Constant
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Wellcome/CRC Institute of Cancer and Developmental Biology, Cambridge, UK.
D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D001755:Blastocyst / Q000166:cytology / Q000502:physiology; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000502:physiology*; D009836:Oligodendroglia / Q000502:physiology; D013234:Stem Cells / Q000502:physiology; D018808:Transcription Factor AP-1 / Q000502:physiology; D014981:Xenopus
D018808:Transcription Factor AP-1