title: Double contrast MR imaging with iron colloid and Gd-DTPA in cholangiocellular carcinoma.
abstract: Double contrast MR imaging with combined use of chondroitin sulfate iron colloid (CSIC) and Gd-DTPA was attempted in 3 cases of cholangiocellular carcinoma (CCC). In all cases, nonenhanced spin echo T1- and T2-weighted images, and T1-weighted images after i.v. injection of Gd-DTPA were obtained. Within one week, the MR sequences were repeated one hour after i.v. injection of CSIC. Double contrast (CSIC/Gd-DTPA) T1-weighted imaging was evaluated and compared with the other sequences in terms of tumor detectability, tumor spreading and tumor characterization. Double contrast MR imaging was comparable in tumor detectability and superior as to the evaluation of spreading and characterization to the other MR imaging modalities.
authors.affiliation: Department of Radiology, Tottori University School of Medicine, Yonago, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Suto
authors.forename: Y
authors.initials: Y
authors.lastname: Shimatani
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: M
authors.initials: M
authors.lastname: Kamba
authors.forename: Y
authors.initials: Y
authors.lastname: Ohuchi
authors.forename: F
authors.initials: F
authors.lastname: Kodama
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: Y
authors.initials: Y
authors.lastname: Ohta
mesh_terms: D001650:Bile Duct Neoplasms / Q000175:diagnosis*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D018281:Cholangiocarcinoma / Q000175:diagnosis*; D002809:Chondroitin Sulfates; D003102:Colloids; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D007501:Iron; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*
chemical_list: D003102:Colloids; D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D002809:Chondroitin Sulfates; D005682:Gadolinium; D007501:Iron; D019786:Gadolinium DTPA