Late recurrence of Wegener's granulomatosis presenting as solitary upper lobe pulmonary mass.
Recurrent Wegener's granulomatosis (WG) was diagnosed in a 40 year old man presenting with a solitary mass in the right lung apex and with possible lymph node enlargement in the anterior mediastinum, resembling malignancy. Eight years previously, a first episode of WG involving the upper airways and kidneys, but not the lungs, had been successfully treated with prednisolone and cyclophosphamide, which could be stopped after 2 yrs. The antineutrophil cytoplasmic antibody titres (anti-protease 3), which had been very high during the first disease episode, failed to predict the recurrence.
van der Werf
T S
TS
Dept of Pulmonary Diseases, Intensive and Respiratory Care, Groningen University Hospital, The Netherlands.
Stegeman
C A
CA
Meuzelaar
K J
KJ
Timens
W
W
D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000032:analysis; D014890:Granulomatosis with Polyangiitis / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D011859:Radiography; D012008:Recurrence
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies