title: Glycoprotein E of pseudorabies virus and homologous proteins in other alphaherpesvirinae.
abstract: This paper reviews biological properties of glycoprotein E (gE) of pseudorabies virus (Aujeszky's disease virus) and homologous proteins in other alphaherpesvirinae. It focuses on the gene encoding gE, conserved regions in the gE protein and its homologs, the complex of gE and gI, biological functions of gE in vitro and in vivo, the role of gE in latency and the role of gE in the induction of humoral and cellular immune responses. Special emphasis is placed on the use of gE as a marker protein in the control and eradication of pseudorabies virus.
authors.affiliation: Central Veterinary Institute (CDI-DLO), Lelystad, The Netherlands.
authors.forename: L
authors.initials: L
authors.lastname: Jacobs
mesh_terms: D018138:Alphaherpesvirinae / Q000737:chemistry*; D000818:Animals; D017124:Conserved Sequence; D011558:Herpesvirus 1, Suid / Q000737:chemistry* / Q000235:genetics / Q000502:physiology; D011557:Pseudorabies / Q000276:immunology / Q000821:virology; D022421:Pseudorabies Vaccines; D009626:Terminology as Topic; D014759:Viral Envelope Proteins / Q000737:chemistry / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D014764:Viral Proteins / Q000235:genetics / Q000502:physiology; D014765:Viral Vaccines / Q000276:immunology
chemical_list: D022421:Pseudorabies Vaccines; D014759:Viral Envelope Proteins; D014764:Viral Proteins; D014765:Viral Vaccines; C089580:glycoprotein E, Suid herpesvirus 1; C042966:pseudorabies virus glycoproteins