[Changes in erythrocyte fluidity, fragility and deformability and serum lipid peroxide content in early burn period].
We have observed RBC membrane fluidity, serum lipid peroxide, RBC deformability and fragility in 10 burn patients on PBD 2.3-5 and 6-10. The results showed that there was a reduction of RBC membrane fluidity and, on the contrary, there was an elevation in the contents of serum lipid peroxide and RBC deformability and fragility (All P < 0.01). We consider that damage of RBC membrane by free radicals may be one of the reasons of the above changes, and anti-free radical drugs may be beneficial in protecting RBC structure and functions and blood circulation.
Gu
T
T
Jishuitan Hospital, Beijing.
Sun
Y
Y
D000328:Adult; D002056:Burns / Q000097:blood*; D002648:Child; D004907:Erythrocyte Deformability; D004910:Erythrocyte Membrane / Q000502:physiology*; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008560:Membrane Fluidity
D008054:Lipid Peroxides