[The interdisciplinary aspects of notalgia paraesthetica].
For 3 years a 75-year-old man with type II diabetes had been suffering from paroxysmal pruritus in a circumscribed area of brown discoloration of the skin over the left should blade. This condition, also known as notalgia paraesthetica, is a rare, but perhaps underdiagnosed, neurocutaneous entity, a largely sensory neuropathy due to a muscular compression phenomenon. In this case histological examination of a biopsy specimen showed focal acanthosis, obvious basal hyperpigmentation and discrete perivascular lymphocytic infiltration with numerous melanophages. At first, glucocorticoids were administered unsuccessfully against the distressing pruritus. Purely symptomatic local capsaicin treatment decreased the pruritus temporarily. Endocrinological diagnosis failed to demonstrate multiple endocrine neoplasia (MEN) syndrome 2A, which has been frequently described in association with notalgia paraesthetica.
Wlotzke
U
U
Dermatologische Klinik, Universität Regensburg.
Stolz
W
W
Hohenleutner
U
U
Dorfmüller
P
P
Korting
H C
HC
Landthaler
M
M
D000368:Aged; D001416:Back Pain / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D001706:Biopsy; D002211:Capsaicin / Q000008:administration & dosage; D002908:Chronic Disease; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003929:Diabetic Neuropathies / Q000188:drug therapy / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D018813:Multiple Endocrine Neoplasia Type 2a / Q000175:diagnosis; D010292:Paresthesia / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D010859:Pigmentation Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011537:Pruritus / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D012867:Skin / Q000473:pathology
D002211:Capsaicin
Interdisziplinäre Aspekte der Notalgia paraesthetica.