[Effect of Leontopodium leontopodioides (Willd.) Beauv. on inflammation induced by animal reversed passive arthus (RPA)].
The extract from Leontopodium leontopodioides 50-100mg/kg ip has been proved able to suppress the swelling of normal or adrenalectomised rat hind paws induced by RPA, and strongly inhibit the cutaneous hemorrhage of animals induced by RPA, lysosome or lysosome of broken membrane. It has also been shown that the extract 100 mg/kg ip can markedly inhibit the migration of leukocytes. These suggest that the anti-inflammatory properties of the extract are not dependent on the pituitary-adrenal system or membrane of lysosome.
Li
L Y
LY
Jilin Provincial Academy of Traditional Chinese Medicine and Materia Medica, Changchun.
Ye
J M
JM
Yin
H
H
Zhu
Y M
YM
Tian
J M
JM
Gao
F
F
D000818:Animals; D001183:Arthus Reaction / Q000188:drug therapy*; D002464:Cell Migration Inhibition; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use* / Q000633:toxicity; D004487:Edema / Q000188:drug therapy; D006168:Guinea Pigs; D006470:Hemorrhage / Q000188:drug therapy; D008297:Male; D051379:Mice; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal