A case of acute renal failure caused by thrombosis of both renal arteries.
A patient developed an occlusion of both renal arteries by extension of a thrombosis of the infra-renal aorta to the superior mesenteric artery. He presented with classical features of acute renal ischemia: lumbar pain, nausea, vomiting, anuria. Since surgery and intra-arterial thrombolytic therapy were not feasible, we performed two peripheral intravenous (i.v.) perfusions of 50 mg Recombinant Tissue-Type Plasminogen Activator (r-tPA) given at 24 hours interval. During the next month serum creatinine decreased from 8.8 mg/dl to 2 mg/dl and the creatinine clearance rose from 0 to 20 ml/minute. The patient never required any dialysis. Seven months later his renal function remains stable.
François
D
D
Department of Internal Medicine, Centre Hospitalier de Lorraine, Saint-Mard, Belgium.
Delgrange
B
B
D058186:Acute Kidney Injury / Q000209:etiology*; D015901:Angiography, Digital Subtraction; D001018:Aortic Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D001027:Aortography; D003404:Creatinine / Q000097:blood; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000150:complications* / Q000000981:diagnostic imaging; D013927:Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
D006493:Heparin; D003404:Creatinine; D010959:Tissue Plasminogen Activator