[Experimental renal transplantation of cirrhotic donors. I. Morphologic, immunofluorescence, and ultrastructural study].
The cirrhotic kidney can be successfully transplanted into healthy recipients. The histological lesions have not been well defined or correlated with the functional changes observed in cirrhosis. Methods to induce experimental cirrhosis in the rat that reliably reproduce this disease have been developed. The development of microsurgical techniques have made it possible to perform transplantation in the rat. We analyzed the renal lesions of cirrhotic rats and the evolution of the graft after transplantation into a healthy rat.
Fernández Gómez
J M
JM
Servicio de Urología, Residencia Covadonga, Hospital Central de Asturias, España.
Concepción Masip
T
T
Val Bernal
J F
JF
Arias Rodríguez
M
M
D000818:Animals; D005355:Fibrosis; D005455:Fluorescent Antibody Technique; D006417:Hematuria; D007668:Kidney / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D016030:Kidney Transplantation / Q000473:pathology*; D009929:Organ Size; D051381:Rats; D011917:Rats, Inbred Lew; D014019:Tissue Donors
Trasplante renal experimental de donantes cirróticos I. Estudio morfológico, de inmunofluorescencia y ultraestructural.