[Effects of petroleum ether extract of Peucedanum praeruptorum Dunn on rabbit trachea smooth muscles].
The contractions of isolated rabbit trachea smooth muscles by acetylcholine and potassium chloride were attenuated by petroleum ether extract of Peucedanum praeruptorum pretreatment. The dose-effect curve of acetylcholine was shifted to the right, and the maximal response was diminished. The effect was non-competitive and dose-dependent.
Jin
X
X
China Medical University, Shenyang.
Zhang
X H
XH
Zhao
N C
NC
D000109:Acetylcholine / Q000037:antagonists & inhibitors; D000473:Alkanes / Q000494:pharmacology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D009126:Muscle Relaxation / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects*; D011189:Potassium Chloride / Q000037:antagonists & inhibitors; D011817:Rabbits; D014132:Trachea / Q000187:drug effects
D000473:Alkanes; D004365:Drugs, Chinese Herbal; D011189:Potassium Chloride; D000109:Acetylcholine; C004544:naphtha