Nonoperative management of esophageal strictures following esophagomyotomy for achalasia.
The optimal management of reflux-induced esophageal strictures that occur after esophagomytomy for achalasia is uncertain. This paper presents our experience with the nonsurgical treatment of postesophagomyotomy strictures in achalasia patients using endoscopic dilation and gastric acid suppression. Six patients with achalasia who had undergone prior esophagomyotomy subsequently developed recurrent dysphagia and were found to have an esophageal stricture. Esophagrams typically showed a markedly dilated esophagus with a narrowed, sharply angulated gastroesophageal junction. Esophageal manometry confirmed esophageal aperistalsis and, when measured, the LES pressure was < 5 mm Hg. Endoscopy showed esophageal inflammation and a fixed stricture at the gastroesophageal junction. Strictures were dilated under direct visualization using through-the-scope balloon dilators. Patients began gastric acid suppressive treatment at the same time. Five patients who remained symptomatic underwent repeat endoscopy, which demonstrated improvement in esophagitis. Dilation was then repeated with a larger balloon dilator. Over a mean follow-up period of 3.8 years, the average number of repeat dilations per patient was 3.6 (range: 0-12). All patients had symptomatic improvement and weight gain. No patient required surgery. We conclude that esophageal strictures after esophagomyotomy for achalasia can be safely treated using endoscopic dilation and gastric acid suppression, thus avoiding the need for reoperation.
Parkman
H P
HP
Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
Ogorek
C P
CP
Harris
A D
AD
Cohen
S
S
D000368:Aged; D000863:Antacids / Q000008:administration & dosage; D002404:Catheterization / Q000295:instrumentation / Q000379:methods; D003131:Combined Modality Therapy; D003680:Deglutition Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D004931:Esophageal Achalasia / Q000150:complications / Q000601:surgery*; D004940:Esophageal Stenosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D020701:Esophagoscopes; D004945:Esophagoscopy / Q000379:methods; D004947:Esophagus / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods*; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D012189:Retrospective Studies; D011795:Surveys and Questionnaires
D000863:Antacids