Protective action of a herbal preparation Liv-52 against beryllium toxicity in rats.
An Ayurvedic medicine, Liv-52 has been studied as a prophylactic against beryllium induced toxicity in rats. Administration of beryllium per se caused severe degenerative and necrotic changes in liver, kidney, lungs and spleen. Its administration reduced glycogen content, activity of alkaline phosphatase and adenosine triphosphatase in these organs. On the contrary, activities of acid phosphatase and glucose-6-phosphatase were increased significantly. In Liv-52 primed rats significant recoupment was observed in all the parameters.
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School of Studies in Zoology, Jiwaji University, Gwalior, India.
Mathur
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Prakash
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D000469:Alkaline Phosphatase / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001608:Beryllium / Q000037:antagonists & inhibitors* / Q000633:toxicity; D002614:Chelating Agents / Q000494:pharmacology*; D004338:Drug Combinations; D005260:Female; D006003:Glycogen / Q000378:metabolism; D007668:Kidney / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
D002614:Chelating Agents; D004338:Drug Combinations; D010936:Plant Extracts; C002614:Liv 52; D006003:Glycogen; D000469:Alkaline Phosphatase; D001608:Beryllium