title: [Heart defects in rheumatoid arthritis patients (the results of a multiyear prospective clinico-echocardiographic study)].
abstract: The analysis of life-time diagnosis of valvular heart disease in rheumatoid arthritis (RA) patients has been made basing on a long-term clinico-echocardiographic investigation. Within 18-year follow-up valvular disease was revealed in 17 out of 214 RA patients (7.9%). Only 3 patients developed the disease in childhood prior to RA diagnosis. In 8 patients the diagnosis of valvular disease was established in the presence of RA, in 6 RA patients the disease was determined during the follow-up period. Mitral stenosis, aortal stenosis, combined mitral valve incompetence, combined aortal defect, mitral defect and tricuspid incompetence, combined mitral defect and pulmonary artery valvular incompetence were detected in 2, 2, 3, 1, 1, and 1 patients, respectively. Valvular disease occurs more frequently in progredient seropositive RA uncontrollable by on-going therapy. The authors emphasize the value of a prospective clinical echocardiographic examination of RA patients in early diagnosis of valvular disease in them. Frequent valvular lesions in RA patients dictate the need of persistent antirheumatic therapy to inhibit the activity and prevent progression of the disease.
authors.forename: E N
authors.initials: EN
authors.lastname: Nemchinov
authors.forename: M Z
authors.initials: MZ
authors.lastname: Kanevskaia
authors.forename: N V
authors.initials: NV
authors.lastname: Chichasova
authors.forename: L M
authors.initials: LM
authors.lastname: Telepneva
authors.forename: A A
authors.initials: AA
authors.lastname: Krel'
mesh_terms: D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000000981:diagnostic imaging*; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging* / Q000453:epidemiology; D018450:Disease Progression; D004452:Echocardiography / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging*; D011379:Prognosis; D011446:Prospective Studies; D012214:Rheumatic Heart Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology; D013997:Time Factors
vernacular_title: Poroki serdtsa u bol'nykh revmatoidnym artritom (rezul'taty mnogoletnego prospektivnogo kliniko-ékhokardiograficheskogo issledovaniia).