[Transplantation of pedicled gastric wall flaps to the intestines in Wistar rats].
The pedicled gastric wall flaps of Wistar rats were transplanted to their duodenum, jejunum and colon respectively. After the operation the rats were killed at the 3rd, 6th, 9th and 12th month respectively. Intestinal metaplasia (IM) was observed in all the gastric grafts transplanted to the intestines under photomicroscope, TEM and SEM. Alkaline phosphatase positive IM was seen in the gastric graft mucosa transplanted to the duodenum and jejunum. The results showed that the formation of IM of the gastric mucosa may be related to a change of the microenvironment around the tissues and that gastric mucosa may differentiate into intestinal mucosa by the increase of pH value.
Li
C Q
CQ
Department of Gastroenterology, Southwest Hospital, Third Military Medical College, Chongqing.
Liu
W W
WW
Fang
D C
DC
D000818:Animals; D003106:Colon / Q000601:surgery; D004386:Duodenum / Q000601:surgery; D005753:Gastric Mucosa / Q000473:pathology* / Q000637:transplantation*; D007422:Intestines / Q000601:surgery*; D007583:Jejunum / Q000601:surgery; D008297:Male; D008679:Metaplasia; D051381:Rats; D017208:Rats, Wistar