title: UCE1022, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from Paecilomyces.
authors.forename: N
authors.initials: N
authors.lastname: Fujii
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: K
authors.initials: K
authors.lastname: Ando
authors.forename: T
authors.initials: T
authors.lastname: Agatsuma
authors.forename: Y
authors.initials: Y
authors.lastname: Saitoh
authors.forename: K
authors.initials: K
authors.lastname: Gomi
authors.forename: Y
authors.initials: Y
authors.lastname: Nishiie
authors.forename: H
authors.initials: H
authors.lastname: Nakano
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002166:Camptothecin / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004249:DNA Damage; D004264:DNA Topoisomerases, Type I / Q000187:drug effects* / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D009279:Naphthacenes; D009284:Naphthols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010143:Paecilomyces / Q000737:chemistry / Q000378:metabolism*
chemical_list: D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes; D009284:Naphthols; C089612:UCE 1022; D004264:DNA Topoisomerases, Type I; D002166:Camptothecin