Adrenoleukodystrophy: cortical hypoperfusion demonstrated with 99mTc-HMPAO SPECT.
Regional cerebral blood flow was investigated in an 8-year-old boy with adrenoleukodystrophy by single photon emission computed tomography. The use of 99mTc-hexamethylpropylene amine oxime revealed markedly reduced blood flow in the occipital, parietal, and temporal cortical gray matter, in addition to the anticipated reduction in white matter. The area with a decreased blood flow was more extensive than that detected by x-ray computed tomography.
al Suhaili
A R
AR
Department of Nuclear Medicine, Tawam Hospital, United Arab Emirates.
Hertecant
J
J
Sztriha
L
L
D000326:Adrenoleukodystrophy / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001921:Brain / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation; D002648:Child; D003072:Cognition Disorders / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime