T-cell lymphoma of the tonsil with Ki-1 antigen expression.
A 52-year-old woman was admitted to our hospital with a fever and swelling of the tonsils and lymph nodes. A tonsillectomy was performed and she was diagnosed as having non-Hodgkin's lymphoma of T-cell phenotype. Genotypic analysis revealed a rearrangement of the T-cell receptor gene, but not of the immunoglobulin genes. The neoplastic cells of the tonsils also expressed the Ki-1 antigen. The clinical course was aggressive with peripheralization of the neoplastic cells, and the patient died of respiratory failure.
Yoshioka
K
K
First Department of Internal Medicine, Matsushita Memorial Hospital, Osaka.
Hirayama
Y
Y
Andachi
H
H
D015139:Blotting, Southern; D005260:Female; D015321:Gene Rearrangement; D015329:Gene Rearrangement, T-Lymphocyte; D005803:Genes, Immunoglobulin; D005838:Genotype; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis*; D016399:Lymphoma, T-Cell / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D008875:Middle Aged; D010641:Phenotype; D014067:Tonsillar Neoplasms / Q000235:genetics / Q000276:immunology* / Q000473:pathology
D017730:Ki-1 Antigen