title: Functional outcome in handsewn versus stapled ileal pouch-anal anastomosis.
abstract: Eighty-eight of 119 patients who underwent ileal pouch-anal anastomosis for ulcerative colitis were evaluated. Forty patients had a handsewn anastomosis (Hs) with mucosectomy, and 48 had a stapled anastomosis (St). In each patient, we evaluated operative, morphologic, functional, and manometric features. The results in the Hs and St groups were similar when the anastomosis was within 1 cm of the dentate line. In particular, there was no correlation between the type of anastomosis and the number of bowel movements in a 24-hour period, the presence of the urge to defecate, and the use of antidiarrheal drugs. Leakage was significantly higher in the Hs group, even when the anastomosis was less than 1 cm from the dentate line. Pouchitis was more frequent in the Hs group, and, within this group, among those with a short distance between the anastomosis and the dentate line. No correlations were found between the presence of columnar epithelium or active colitis in the mucosa below the anastomosis, the functional outcomes, and the incidence of pouchitis.
authors.affiliation: II Clinica Chirurgica, University of Bologna, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Gozzetti
authors.forename: G
authors.initials: G
authors.lastname: Poggioli
authors.forename: F
authors.initials: F
authors.lastname: Marchetti
authors.forename: S
authors.initials: S
authors.lastname: Laureti
authors.forename: G L
authors.initials: GL
authors.lastname: Grazi
authors.forename: M
authors.initials: M
authors.lastname: Mastrorilli
authors.forename: S
authors.initials: S
authors.lastname: Selleri
authors.forename: L
authors.initials: L
authors.lastname: Stocchi
authors.forename: M
authors.initials: M
authors.lastname: Di Simone
mesh_terms: D011125:Adenomatous Polyposis Coli; D000328:Adult; D003093:Colitis, Ulcerative / Q000503:physiopathology / Q000601:surgery*; D003672:Defecation; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D015994:Incidence; D007249:Inflammation; D008297:Male; D008365:Manometry; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D011312:Pressure; D016737:Proctocolectomy, Restorative / Q000009:adverse effects / Q000379:methods*; D011788:Quality of Life; D012189:Retrospective Studies; D017792:Surgical Stapling; D013536:Suture Techniques; D016896:Treatment Outcome