Organ preservation.
Our clinical transplantation results have been very satisfying, with about 90% graft survival after 1 year. Currently, preservation of the liver, pancreas, and kidney, although not ideal, appears to meet all our clinical needs. Improvements in heart and lung preservation are needed and will result in increasing the number of cadaveric organs available for patients with end-stage intrathoracic organ diseases. In the future, machine perfusion may become the standard method for organ preservation for most organs because of the excellent preservation results and long-term preservation achieved.
D'Alessandro
A M
AM
Department of Surgery, University of Wisconsin Medical School, Madison.
Southard
J H
JH
Love
R B
RB
Belzer
F O
FO
D000241:Adenosine / Q000627:therapeutic use; D000493:Allopurinol / Q000627:therapeutic use; D003362:Cost-Benefit Analysis; D015925:Cryopreservation / Q000191:economics / Q000379:methods* / Q000639:trends; D005978:Glutathione / Q000627:therapeutic use; D006085:Graft Survival; D006785:Hospitals, University; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D009926:Organ Preservation / Q000009:adverse effects / Q000191:economics / Q000379:methods* / Q000639:trends; D019188:Organ Preservation Solutions; D016377:Organ Transplantation; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D011887:Raffinose / Q000627:therapeutic use; D013997:Time Factors; D014015:Tissue Banks; D014922:Wisconsin
D007328:Insulin; D019188:Organ Preservation Solutions; C055206:University of Wisconsin-lactobionate solution; D000493:Allopurinol; D005978:Glutathione; D000241:Adenosine; D011887:Raffinose