Polymerase chain reaction and HIV.
In this article, the synergistic progress for both polymerase chain reaction (PCR) technology and HIV-1 is reviewed. The latest developments in standard PCR technology for the detection and quantitation of HIV-1 DNA molecules are summarized. In addition, examples of applications selected from the fields of HIV-1 diagnosis, epidemiology, pathogenesis, and therapy monitoring are presented. Finally, the limitations of standard PCR procedures in HIV-1 research and clinical settings are discussed.
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Immune Response Corporation, Carlsbad, California.
D000163:Acquired Immunodeficiency Syndrome / Q000151:congenital / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D000465:Algorithms; D004279:DNA, Viral / Q000032:analysis; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods
D004279:DNA, Viral