title: Systemic strongyloidiasis in patients infected with the human immunodeficiency virus. A report of 3 cases and review of the literature.
abstract: We report 3 cases of systemic strongyloidiasis in HIV-infected individuals and review 11 additional cases reported in the English-language literature. Systemic strongloidiasis is a rare and potentially fatal complication of late-stage HIV disease. A combination of gastrointestinal and respiratory symptoms in an HIV-infected patient who has been to an endemic area should prompt the clinician to search for S. stercoralis in stool and sputum specimens. Treatment failures occur commonly, and careful follow-up is warranted. New antihelminthic drugs (such as ivermectin) seem promising and need to be evaluated in controlled studies.
authors.affiliation: Pulmonary and Critical Care Division, Brown University School of Medicine, Providence, Rhode Island.
authors.forename: J C
authors.initials: JC
authors.lastname: Celedon
authors.forename: U
authors.initials: U
authors.lastname: Mathur-Wagh
authors.forename: J
authors.initials: J
authors.lastname: Fox
authors.forename: R
authors.initials: R
authors.lastname: Garcia
authors.forename: P M
authors.initials: PM
authors.lastname: Wiest
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000469:parasitology*; D000328:Adult; D000818:Animals; D006801:Humans; D008297:Male; D008875:Middle Aged; D017171:Strongyloides stercoralis; D013322:Strongyloidiasis / Q000175:diagnosis / Q000276:immunology*