title: [Predictive value of ergospirometry in preoperative assessment of risk factors before lung resections].
abstract: Surgical resection for lung cancer provides the only real chance for cure. However, there is a high risk of postoperative complications including death for patients with pulmonary dysfunction. Therefore preoperative identification of patients at risk is necessary. Apart from history and physical examination three tests are currently used: 1. resting lung function (RFL), 2. invasive measurement of pulmonary vascular resistance (PVR) and 3. exercise testing with measurement of oxygen consumption (VO2). Main studies in the literature report the probability of abnormal tests for prediction of pulmonary complications (positive predictive value) and the probability of normal tests for prediction of uneventful outcome (negative predictive value) as follows: [table: see text] In conclusion, the "ideal" test predictive for morbidity and mortality after lung resection has not been found. The positive predictive values of RLF and PVR are disappointing, while the negative predictive values are acceptable. Measurement of VO2 is simple, noninvasive and might predict survivable morbidity, as suggested in the literature. Obviously, additional studies are necessary.
authors.affiliation: Klinik III für Innere Medizin, Universität zu Köln.
authors.forename: G
authors.initials: G
authors.lastname: Pothoff
authors.forename: K
authors.initials: K
authors.lastname: Wassermann
authors.forename: U J
authors.initials: UJ
authors.lastname: Winter
authors.forename: H H
authors.initials: HH
authors.lastname: Hilger
mesh_terms: D005080:Exercise Test; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D008176:Lung Volume Measurements; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000401:mortality / Q000517:prevention & control*; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012131:Respiratory Insufficiency / Q000401:mortality / Q000517:prevention & control*; D012307:Risk Factors; D013147:Spirometry; D015996:Survival Rate
vernacular_title: Prädiktiver Wert der Spiroergometrie in der präoperativen Abschätzung von Risikopatienten vor Lungenresektionen.