title: [A clinico-immunological analysis of clinical variants of connective tissue dysplasia].
abstract: The clinico-immunogenetic analysis of 47 patients with Marfan's syndrome and 83 patients with chest deformities combined with valvular prolapses and other connective tissues dysplasias elucidated a close relation of HLA-antigens allele variants with clinical dysplasia variants and specific immune alterations. The findings support the suggestion that clinical heterogeneity of connective tissue dysplasia forms results from their pathogenetic heterogeneity.
authors.forename: V M
authors.initials: VM
authors.lastname: Iakovlev
authors.forename: A V
authors.initials: AV
authors.lastname: Glotov
authors.forename: G I
authors.initials: GI
authors.lastname: Nechaeva
authors.forename: V I
authors.initials: VI
authors.lastname: Konenkov
mesh_terms: D000293:Adolescent; D000328:Adult; D000483:Alleles; D000917:Antibody Formation; D003240:Connective Tissue Diseases / Q000151:congenital / Q000235:genetics / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000097:blood / Q000235:genetics; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000097:blood; D008297:Male; D008382:Marfan Syndrome / Q000235:genetics / Q000276:immunology; D008875:Middle Aged; D013909:Thorax / Q000002:abnormalities
chemical_list: D006680:HLA Antigens; D007136:Immunoglobulins
vernacular_title: Kliniko-immunologicheskiĭ analiz klinicheskikh variantov displazii soedinitel'noĭ tkani.