Hemolytic anemia following succimer administration in a glucose-6-phosphate dehydrogenase deficient patient.
Because of its favorable side effects profile, the oral chelating agent dimercaptosuccinic acid is often used for treatment of lead intoxication. We report a case of a 45-year-old black male with glucose-6-phosphate dehydrogenase deficiency and a 17 year history of occupational lead exposure who developed hemolysis during treatment with dimercaptosuccinic acid for symptomatic lead intoxication.
Gerr
F
F
Division of Environmental and Occupational Health, Emory University School of Public Health, Atlanta, GA 30329.
Frumkin
H
H
Hodgins
P
P
D000743:Anemia, Hemolytic / Q000139:chemically induced*; D015913:Chelation Therapy; D005955:Glucosephosphate Dehydrogenase Deficiency; D006801:Humans; D007855:Lead Poisoning / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000628:therapy*; D004113:Succimer / Q000009:adverse effects*
D004113:Succimer