title: Meningiomas involving the anterior clinoid process.
abstract: We report a series of 34 clinoidal meningiomas treated surgically and analyse the results according to cavernous sinus involvement. Fifteen tumours extended into the cavernous sinus. Only four of these could be resected completely, and global outcome was improved or stable in 10 cases. Overall, 20 tumours had a total resection and 14 had a partial resection. Complete removal of the sphenoid wing, including the anterior clinoid and part of the planum sphenoidale, allows early devascularization of the tumour and minimizes brain retraction when associated with resection of the zygomatic arch. The most frequent postoperative complication was transient CSF leak, occurring in three patients. Two patients died postoperatively, and three suffered permanent complications. There was no recurrence after total removal, but five patients showed signs of progressive tumour growth after partial removal, treated by radiotherapy in three and by surgery in two cases. Twenty patients showed preoperative visual impairment. Outcome of vision was improved or stable in 13 (68%) and worse in six cases (32%). We suggest that progressive visual impairment should lead to aggressive surgical treatment, especially when complete resection of cavernous sinus involvement can be performed.
authors.affiliation: Department of Neurosurgery, University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Risi
authors.forename: A
authors.initials: A
authors.lastname: Uske
authors.forename: N
authors.initials: N
authors.lastname: de Tribolet
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002426:Cavernous Sinus / Q000601:surgery; D016371:Cranial Irradiation; D003952:Diagnostic Imaging; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000098:blood supply / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D008579:Meningioma / Q000098:blood supply / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery; D009460:Neurologic Examination; D012086:Reoperation; D013100:Sphenoid Bone / Q000098:blood supply / Q000601:surgery; D016896:Treatment Outcome