Primary bilateral B-cell renal lymphoma: a case report and review of the literature.
Renal lymphoma is commonly secondary to lymphomatous infiltration of the kidneys in disseminated lymphoma and advanced stage IV disease. We describe a 57-year-old white woman presenting with an acute renal failure due to a bilateral "primary" B-cell lymphoma infiltration of the kidneys. The diagnosis of the lymphoma was made by renal biopsy. The striking feature observed was a destructive infiltration of the kidney by a malignant B-cell lymphoma that left the renal capsule intact, without any sign of secondary localization on the hilar regions. Physical examination did not reveal any peripheral lymphadenopathy or hepatosplenomegaly. A bilateral infiltration of both kidneys was the only feature shown by computed tomography and renal angiography. This case raises the question of the occurrence of a primary B-cell lymphoma in a nonlymphoid organ, which was diagnosed by renal biopsy at a time when the development was exclusively renal in origin.
Brouland
J P
JP
Unité INSERM U 28, Département de Néphrologie, Hôpital Broussais, Paris, France.
Meeus
F
F
Rossert
J
J
Hernigou
A
A
Gentric
D
D
Jacquot
C
C
Diebold
J
J
Nochy
D
D
D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D016393:Lymphoma, B-Cell / Q000473:pathology*; D008875:Middle Aged