title: The end of fertility: age, fecundity and fecundability in women.
abstract: Onset of capacity for childbearing in women is dated biologically by menarche, although actual onset may be delayed. The end of childbearing is less understood but recent demographic and biological research on fertility at older ages in clarifying the end of fertility. The demographic view of declining fertility with age is based on age-specific fertility in natural fertility populations, artificial insemination and pregnancy rates by age and World Fertility Survey data. New data from the Demographic and Health Surveys on exposure to the risk of pregnancy shows that whereas older women biologically need longer exposure to pregnancy, exposure declines on behavioural grounds such as duration of marriage. Actual fecundity is obscured by factors of fecundability. Recent research on medically assisted conception is adding to the understanding of declining fecundity with age, especially the relative contributions of endometrial and ovarian ageing. This paper reviews the available information on declining fertility with age and discusses the implications of the extension of fertility through new medical technologies.
authors.affiliation: World Health Organization, Geneva, Switzerland.
authors.forename: O
authors.initials: O
authors.lastname: Frank
authors.forename: P G
authors.initials: PG
authors.lastname: Bianchi
authors.forename: A
authors.initials: A
authors.lastname: Campana
mesh_terms: D000328:Adult; D000367:Age Factors; D003431:Cross-Cultural Comparison; D005260:Female; D006801:Humans; D007316:Insemination, Artificial, Heterologous / Q000706:statistics & numerical data; D008593:Menopause; D008875:Middle Aged; D011247:Pregnancy; D012725:Sexual Behavior