Peritoneal ventilation: an animal model of extrapulmonary ventilation in experimental adult respiratory distress syndrome.
Adult respiratory distress syndrome (ARDS) is a critical medical problem in which severe arterial hypoxemia is often poorly responsive to conventional modes of mechanical ventilation. We studied the efficiency of mechanical ventilation of the peritoneal cavity in rabbits with experimental ARDS caused by lung lavage. The study shows that peritoneal ventilation is significantly effective in oxygenation of hypoxemic animals with ARDS and is also effective for carbon dioxide elimination. Peritoneal ventilation may be considered as an investigational method for extrapulmonary oxygenation in severe intractable hypoxemia caused by ARDS.
Barr
J
J
Pediatric Intensive Care Unit, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel.
Livne
A
A
Lushkov
G
G
Vinograd
I
I
Efrati
Y
Y
Ballin
A
A
Lahat
E
E
Eshel
G
G
D000818:Animals; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000097:blood; D004195:Disease Models, Animal; D005069:Evaluation Studies as Topic; D010100:Oxygen / Q000097:blood; D010529:Peritoneal Cavity; D011817:Rabbits; D012121:Respiration, Artificial / Q000379:methods*; D012128:Respiratory Distress Syndrome / Q000097:blood / Q000503:physiopathology / Q000628:therapy*
D002245:Carbon Dioxide; D010100:Oxygen