[The efficacy and side reactions in humans immunized with Danish strain of dried BCG of Shanghai].
A procedure of keeping Danish BCG strain 2 is reported. The strain is cultivated in Bile potato Medium and Suton Potato Medium alternatively with incubation periods of two weeks. Lyophilized vaccine produced by using seeds derived from this strain gives better immunogenicity and lower side reaction to new-born babies and has better thermostability in compare with vaccines derived from strains of Beijing, Brazil, CCCP, France of Hungary.
Zhu
G
G
Shanghai Institute of Biological Products.
Tao
H
H
Huang
Z
Z
D000818:Animals; D001500:BCG Vaccine / Q000009:adverse effects / Q000145:classification / Q000276:immunology*; D004355:Drug Stability; D006801:Humans; D007231:Infant, Newborn; D051379:Mice; D009163:Mycobacterium bovis / Q000254:growth & development / Q000276:immunology*; D012692:Serial Passage; D014611:Vaccination
D001500:BCG Vaccine