title: [Immunomodulatory function of polysaccharide of Hericium erinaceus].
abstract: Hericium erinaceus is a Chinese herbal medicine. The Apollo oral liquid contains polysaccharide of H. erinaceus (PHE). The effects of PHE on proliferation of mice T and B lymphocytes were studied. Results showed that (1) 3-fold proliferation of thymocytes was demonstrated when PHE were administrated with Con A than Con A alone. Such effect on thymocyte was not observed when PHE was used alone. (2) Proliferation of spleen lymphocytes was also stimulated when PHE were taken together with lipopolysaccharide, which was 50% and 3 times stronger than that of using lipopolysaccharide and PHE alone respectively.
authors.affiliation: Zhejiang College of TCM, Hangzhou.
authors.forename: H M
authors.initials: HM
authors.lastname: Xu
authors.forename: Z H
authors.initials: ZH
authors.lastname: Xie
authors.forename: W Y
authors.initials: WY
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001487:Basidiomycota / Q000737:chemistry; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D051379:Mice; D011134:Polysaccharides / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology; D013601:T-Lymphocytes / Q000187:drug effects
chemical_list: D004365:Drugs, Chinese Herbal; D011134:Polysaccharides