A new type of antimicrobial phenolics produced by plant peroxidase and its possible role in the chemical defense systems against plant pathogens.
Syringaldehyde readily reacted in the horse-radish peroxidase (HRPOD) system. The ethyl acetate extract of the reaction mixture showed a marked antimicrobial activity against bacteria and fungi. After repeated column chromatography three potential antimicrobial compounds were obtained from the extract. The structural elucidation of active compounds was achieved by a combination of spectroscopic techniques and chemical modification.
Kobayashi
A
A
Department of Agricultural Science, Okayama University, Japan.
Koguchi
Y
Y
Kanzaki
H
H
Kajiyama
S
S
Kawazu
K
K
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D001230:Aspergillus / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D001547:Benzaldehydes / Q000378:metabolism* / Q000494:pharmacology; D002963:Cladosporium / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006735:Horseradish Peroxidase / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010636:Phenols / Q000378:metabolism* / Q000494:pharmacology*; D010944:Plants / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001547:Benzaldehydes; D010636:Phenols; C069665:syringaldehyde; D006735:Horseradish Peroxidase