Efficacy and safety of indomethacin 0.1% versus flurbiprofen 0.03% eyedrops in inflammation after argon laser trabeculoplasty. The Belgian Study Group on Glaucoma.
After Argon Laser Trabeculoplasty (ALT), non steroidal anti-inflammatory drugs (Indomethacin 1% suspension and Flurbiprofen 0.03% solution) were shown to be efficient in the management of post laser inflammation. To evaluate the efficacy and safety of Indomethacin 0.1% solution versus Flurbiprofen 0.03% eyedrops in that purpose. 64 patients suffering from glaucoma were recruited in a multicenter randomized double masked study. The results demonstrate that Indomethacin 0.1% eyedrops is as efficient as Flurbiprofen 0.03% in terms of control of post ALT inflammation, with a good tolerance.
Goethals
M
M
Ophthalmic Clinic, University Hospital St. Raphael, Leuven, Belgium.
Missotten
L
L
D004311:Double-Blind Method; D004361:Drug Tolerance; D009877:Endophthalmitis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005480:Flurbiprofen / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007429:Intraocular Pressure; D053685:Laser Therapy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D014130:Trabeculectomy / Q000009:adverse effects*
D009883:Ophthalmic Solutions; D005480:Flurbiprofen; D007213:Indomethacin