title: Immunohistochemical study of placental endothelium in physiologic and gestosis-complicated pregnancies.
abstract: In this study we examined the placentae of gestosic patients and controls, with immunoistochemical method and HLA-DR monoclonal antibody, in order to show the role of placental endothelium in gestosic pathology onset. Our results show a marked expression of class II histocompatibility antigens in gestosic placentae with respect to controls. We suppose, in gestosic patients, a role for a particular, genetically determined HLA haplotype which increases disease receptivity.
authors.affiliation: Department of Obstetrics and Gynecology, University of Pisa, Italy.
authors.forename: I
authors.initials: I
authors.lastname: de Luca Brunori
authors.forename: A
authors.initials: A
authors.lastname: Amato
authors.forename: G
authors.initials: G
authors.lastname: Arcidiacono
authors.forename: L
authors.initials: L
authors.lastname: Battini
authors.forename: G
authors.initials: G
authors.lastname: Giusti
authors.forename: P
authors.initials: P
authors.lastname: Scida
authors.forename: M
authors.initials: M
authors.lastname: Simonelli
authors.forename: M
authors.initials: M
authors.lastname: Urbano
authors.forename: M
authors.initials: M
authors.lastname: Filippeschi
mesh_terms: D004727:Endothelium / Q000276:immunology* / Q000473:pathology; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D010920:Placenta / Q000276:immunology* / Q000473:pathology; D011225:Pre-Eclampsia / Q000276:immunology* / Q000473:pathology; D011247:Pregnancy
chemical_list: D006684:HLA-DR Antigens