Serum Cohn fraction IV-1 supports the growth of Giardia lamblia in vitro.
Bovine serum Cohn fractions were substituted for whole bovine serum in TYI-S-33 medium. Only fraction IV-1 supported attachment, cysteine uptake, and growth of Giardia lamblia. Among the mammalian sources tested, only goat and horse fractions showed activities comparable to that of the bovine fraction. Agglutinating immunoglobulins were identified as deleterious agents in human, rat, rabbit, and dog fractions.
Lujan
H D
HD
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.
Byrd
L G
LG
Mowatt
M R
MR
Nash
T E
TE
D000818:Animals; D001798:Blood Proteins / Q000494:pharmacology*; D002417:Cattle; D003470:Culture Media; D016829:Giardia lamblia / Q000254:growth & development*; D006801:Humans
D001798:Blood Proteins; C032309:Cohn fraction IV; D003470:Culture Media