A low flip angle spin-echo technique for producing rapid diffusion weighted MR images.
A method is described for producing rapid diffusion-weighted images using a modified low flip angle imaging technique. Utility of the method is demonstrated by the quantification of diffusion coefficients in a rat model of focal ischemia. The method may be readily applied to animal research studies using NMR research systems with modest gradient capabilities.
Ordidge
R J
RJ
NIH Center for Stroke Research, Department of Neurology, Henry Ford Health Sciences Center, Detroit, MI 48202.
Knight
R A
RA
Helpern
J A
JA
Hugg
J W
JW
D000818:Animals; D002545:Brain Ischemia / Q000473:pathology; D004058:Diffusion; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012815:Signal Processing, Computer-Assisted