Tyrosine-hydroxylase immunoreactive fibres in the rat anterior pituitary.
Tyrosine-hydroxylase (TH)-like immunoreactivity was investigated in normal and oestrogenized rat anterior pituitaries in the light of recent studies showing a TH enzymatic activity in the gland and the presence of TH mRNA in endocrine cells. Sparse TH positive fibres, probably dopaminergic as assessed by the absence of dopamine-beta-hydroxylase (DBH) immunoreactivity, were detected in the anterior pituitary, but the detection of TH immunoreactivity in cells was unsuccessful.
Bayet
M C
MC
Unité INSERM 223, Faculté de Médecine Pitié-Salpêtrière, Paris, France.
Schussler
N
N
Verney
C
C
Peillon
F
F
D000818:Animals; D004299:Dopamine beta-Hydroxylase / Q000032:analysis; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D015870:Gene Expression / Q000187:drug effects; D007150:Immunohistochemistry; D009412:Nerve Fibers / Q000187:drug effects / Q000201:enzymology*; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000187:drug effects / Q000201:enzymology*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis; D051381:Rats; D017208:Rats, Wistar; D012016:Reference Values; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis / Q000096:biosynthesis*
D012333:RNA, Messenger; D004958:Estradiol; D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase