[The late results of intensive chemotherapy (9 months) in severe forms of tuberculosis in children].
The short-course chemotherapy (9 months) in the severe forms of tuberculosis in children is a very modern item. It was very few approached on an international level and relatively short time ago in our country. There were applied the following therapeutical regimens: 3 HRZ2 6 HR2 (in the experimental group) and 3 HR/3 HR2/6 H2 (in the control group). In the granulias and the caseous forms the late results, at 5 years after treatment end, were very good in 100% of cases in both groups. In meningitis clinical very good results (without sequellae) presented a proportion of 70.1% in the experimental group and of 68.2% in the control group (difference statistically non significant). The main advantage of the intensive short course regimens (9 months) comparatively with the "classical" ones (of at least 12 months) consists in reaching finally the same good results but in at least 3 months shorter time interval.
Anastasatu
C
C
Institutul de Pneumoftiziologie Marius Nasta, Bucureşti.
Anastasatu
O
O
Murgoci
G
G
Dobre
M
M
D000293:Adolescent; D000995:Antitubercular Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D012074:Remission Induction; D013997:Time Factors; D014390:Tuberculosis, Meningeal / Q000188:drug therapy* / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000382:microbiology
D000995:Antitubercular Agents
Rezultatele tardive ale chimioterapiei intensive (9 luni) în formele grave de tuberculoză la copil.