[Lipid peroxidation and antioxidant defence in patients with pneumoconiosis and dust-induced bronchitis].
Lipids peroxidation (LP) and antioxidant defence (AD) were compared in the patients facing pneumoconiosis and dust bronchitis. The studied group included 35 patients with suspected pneumoconiosis, 75 patients facing the 1 grade of pneumoconiosis, 43 coniotuberculosis patients and 43 patients with dust bronchitis. Active LP was demonstrated, values and intensities of its stages depended on the origin and severity of disease. AD was characteristically depressed, which necessitates the antioxidant treatment of patients with pneumoconiosis and dust bronchitis.
Kolodub
F A
FA
Kleĭner
A I
AI
Makotchenko
V M
VM
Kashkalda
D A
DA
Martynov
P N
PN
D000328:Adult; D000975:Antioxidants / Q000378:metabolism* / Q000627:therapeutic use; D001991:Bronchitis / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*; D004391:Dust / Q000009:adverse effects; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D016273:Occupational Exposure; D011009:Pneumoconiosis / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*
D000975:Antioxidants; D004391:Dust
Perekisnoe okislenie lipidov i antioksidantnaia zashchita u bolńykh pnevmokoniozom i pylevym bronkhitom.