title: Acute and long-term outcome of directional coronary atherectomy for stable and unstable angina.
abstract: The clinical efficacy and safety of directional coronary atherectomy for the treatment of stable and unstable angina were assessed in 82 patients with stable and 68 patients with unstable angina. Therefore, clinical and angiographic follow-up was obtained in a prospectively collected consecutive series of 150 atherectomy procedures. Restenosis was assessed clinically and by quantitative angiography. The overall clinical success rate of atherectomy for patients with unstable and stable angina was 88% and 91%, respectively. No significant differences were found for in-hospital event rates between the unstable and stable angina groups: death (1.5% vs 0%), myocardial infarction (10% vs 6%), and emergency bypass operation (3% vs 2%). These clinical events were related to the occurrence of abrupt occlusions (8.8% in patients with stable and 6.1% in those with unstable angina; p = NS). Clinical follow-up was achieved in 100% of the patients with stable and unstable angina at a mean interval of 923 and 903 days, respectively. Two-year survival rates were 96% and 97% in the populations with unstable and stable angina, respectively. There were no significant differences with respect to bypass surgery and angioplasty, but event-free survival at 2 years was significantly lower in the unstable (54%) than the stable (69%) angina group. Quantitative coronary angiography did not detect any difference in luminal renarrowing during the 6-month angiographic follow-up period. Although directional coronary atherectomy can be performed effectively in patients with unstable and stable angina, the long-term clinical outcome was less favorable in the unstable angina group.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Catheterization Laboratory, University Hospital Dijkzigt, Erasmus University Rotterdam, The Netherlands.
authors.forename: V A
authors.initials: VA
authors.lastname: Umans
authors.forename: P J
authors.initials: PJ
authors.lastname: de Feyter
authors.forename: J W
authors.initials: JW
authors.lastname: Deckers
authors.forename: D
authors.initials: D
authors.lastname: MacLeod
authors.forename: M
authors.initials: M
authors.lastname: van den Brand
authors.forename: P
authors.initials: P
authors.lastname: de Jaegere
authors.forename: P W
authors.initials: PW
authors.lastname: Serruys
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D000789:Angina, Unstable / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D017225:Atherectomy, Coronary / Q000379:methods; D016009:Chi-Square Distribution; D015331:Cohort Studies; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging / Q000601:surgery; D017023:Coronary Angiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011379:Prognosis; D011446:Prospective Studies; D012008:Recurrence; D015996:Survival Rate