Pressure-volume relationships of the respiratory system in normal cats.
We studied the pressure-volume (PV) relationships of the total respiratory system, lung and chest wall in 8 anesthetized and paralyzed normal adult cats. The PV relationships of the total respiratory system had a sigmoid shape with a relatively linear portion with an alveolar pressure between 0 to +15 cmH2O. The relative impact of the lung and chest wall to the total elastic recoil forces of the respiratory system was approximately equal within a physiological pressure range. The results suggest that measurements of PV relationships of the respiratory system may offer a physiologic basis for accurate interpretation of pulmonary functions, leading to a better therapeutic strategy in animals with lung diseases.
Fujita
M
M
Department of Radiology, School of Veterinary Medicine, Nippon Veterinary and Animal Science University, Tokyo, Japan.
Orima
H
H
Miyasaka
K
K
Takata
M
M
D000818:Animals; D002415:Cats / Q000502:physiology*; D008168:Lung / Q000502:physiology*; D009126:Muscle Relaxation; D010994:Pleura / Q000502:physiology; D011312:Pressure; D011650:Pulmonary Alveoli / Q000502:physiology; D012121:Respiration, Artificial; D012143:Respiratory Physiological Phenomena; D013909:Thorax / Q000502:physiology