title: Lobular carcinoma in situ in a 15-year-old girl: a case report and review of the literature.
abstract: Lobular carcinoma in situ is a clinically occult lesion associated with subsequent development of invasive breast cancer in up to one-third of patients. Lobular carcinoma in situ may be viewed as a marker lesion indicating an increased risk for development of subsequent invasive disease in either breast. Regardless of patient age or diagnosis, excised breast tissue merits thorough pathologic examination. If lobular carcinoma in situ is identified, a thorough search for areas of invasion is warranted. Treatment options are based on the associated risk of invasive carcinoma. Thorough counseling of patients regarding risks and benefits of surgical and nonsurgical treatment options is essential, with marked emphasis on the need for continued lifelong surveillance of unexcised breast tissue.
authors.affiliation: Department of Surgery, Baystate Medical Center.
authors.forename: B L
authors.initials: BL
authors.lastname: Ackerman
authors.forename: C
authors.initials: C
authors.lastname: Otis
authors.forename: K
authors.initials: K
authors.lastname: Stueber
mesh_terms: D000293:Adolescent; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000473:pathology; D002278:Carcinoma in Situ / Q000453:epidemiology* / Q000473:pathology; D018275:Carcinoma, Lobular / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D016462:Mammaplasty; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology* / Q000473:pathology