title: Pregnancies after assisted fertilization for "extreme" male factor: report on three cases.
abstract: Three cases of extreme male factor infertility, not acceptable for conventional IVF, are presented. In the first case, only 30 sluggishly motile spermatozoa were obtained in two ejaculates but treatment with SUZI resulted in a viable singleton pregnancy. In the second case, a combination of microepididymal sperm aspiration, for vasal obstruction after failure of reversal, with intracytoplasmic sperm injection resulted in a viable singleton pregnancy. In the third case, the husband had a vasal reservoir for distal vasal blockage. Sperm from the reservoir with extremely low motility and high antisperm antibody were microinjected by intracytoplasmic sperm injection and this resulted in a triplet pregnancy.
authors.affiliation: London Gynaecology and Fertility Center, United Kingdom.
authors.forename: D
authors.initials: D
authors.lastname: Yang
authors.forename: T
authors.initials: T
authors.lastname: al-Shawaf
authors.forename: C
authors.initials: C
authors.lastname: Redgment
authors.forename: M
authors.initials: M
authors.lastname: Tsirigotis
authors.forename: R
authors.initials: R
authors.lastname: Joshi
authors.forename: I
authors.initials: I
authors.lastname: Craft
mesh_terms: D000328:Adult; D003593:Cytoplasm; D005260:Female; D005306:Fertilization; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D007267:Injections; D007317:Insemination, Artificial, Homologous / Q000379:methods; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D012099:Reproductive Techniques; D015044:Zona Pellucida