title: Bone-origin alkaline phosphatase in plasma by wheat-germ lectin methods in bone disease.
abstract: Bone-origin ALP in plasma may be readily quantified by WG-lectin methods and such measurements (reflecting osteoblastic activity) are useful in a wide variety of bone disorders. The studies summarized here have confirmed that ALP isoenzyme examination by these methods adds tissue specificity and diagnostic sensitivity to total ALP measurement.
authors.affiliation: Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London, UK.
authors.forename: S B
authors.initials: SB
authors.lastname: Rosalki
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D001847:Bone Diseases / Q000175:diagnosis* / Q000201:enzymology*; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary; D001842:Bone and Bones / Q000201:enzymology*; D004796:Clinical Enzyme Tests / Q000379:methods*; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D008297:Male; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis; D012680:Sensitivity and Specificity; D014909:Wheat Germ Agglutinins
chemical_list: D007527:Isoenzymes; D014909:Wheat Germ Agglutinins; D000469:Alkaline Phosphatase