title: High-level multilineage engraftment of human cord blood cells in SCID mice.
abstract: Cord blood is increasingly used as an alternative to bone marrow transplantation in pediatric patients. Therefore, to study cord blood-derived hematopoiesis in vivo we are developing a xenogeneic transplantation model using immunodeficient SCID mice.
authors.affiliation: Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Vormoor
authors.forename: T
authors.initials: T
authors.lastname: Lapidot
authors.forename: F
authors.initials: F
authors.lastname: Pflumio
authors.forename: G
authors.initials: G
authors.lastname: Risdon
authors.forename: B
authors.initials: B
authors.lastname: Patterson
authors.forename: H E
authors.initials: HE
authors.lastname: Broxmeyer
authors.forename: J E
authors.initials: JE
authors.lastname: Dick
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D003114:Colony-Forming Units Assay; D005312:Fetal Blood / Q000166:cytology*; D006085:Graft Survival; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007231:Infant, Newborn; D051379:Mice; D016513:Mice, SCID; D011828:Radiation Chimera; D016511:Severe Combined Immunodeficiency / Q000628:therapy*; D014183:Transplantation, Heterologous