title: [The observance of Ramadan and its repercussion on gastric secretion].
abstract: The influence of the Ramadan on the gastric secretion has been assessed in 13 volunteers. Their basal and pentagastrin-stimulated secretion has been collected before, during and one month after the Ramadan. Gastric activity, pepsin activity, sialic acid bound to glycoprotein, choline and gastrinaemia have been measured. During Ramadan, acid secretion was increased (+ 159%; P = 0.02) and it recovered the pre-Ramadan level, one month later. Pepsin secretion was also increased during the Ramadan (+ 133%; P = 0.05) and it was significantly reduced after Ramadan. The secretion before the Ramadan was related to vagal hypertony, decreased during Ramadan and was substituted by a gastrinic stimulation after the Ramadan. Mucolysis and gastrinaemia were not modified and no duodenogastric reflux was observed during and after the Ramadan. The Ramadan induces an increase of acid and pepsin secretion. This increase was reversed when Ramadan stopped. These gastric secretion modifications are likely involved in the increase of dyspeptic symptoms observed during the Ramadan.
authors.affiliation: Casablanca, Maroc, INSERM U 10 et Biochimie B, CHU X.-Bichat, Paris.
authors.forename: F
authors.initials: F
authors.lastname: Hakkou
authors.forename: A
authors.initials: A
authors.lastname: Tazi
authors.forename: L
authors.initials: L
authors.lastname: Iraqui
authors.forename: C
authors.initials: C
authors.lastname: Celice-Pingaud
authors.forename: J
authors.initials: J
authors.lastname: Vatier
mesh_terms: D000328:Adult; D002794:Choline / Q000378:metabolism; D005215:Fasting / Q000502:physiology*; D005744:Gastric Acid / Q000378:metabolism*; D006801:Humans; D007514:Islam; D008297:Male; D010418:Pentagastrin / Q000378:metabolism; D010434:Pepsin A / Q000378:metabolism; D012016:Reference Values; D012068:Religion and Medicine; D012794:Sialic Acids / Q000378:metabolism
chemical_list: D012794:Sialic Acids; D010434:Pepsin A; D010418:Pentagastrin; D002794:Choline
vernacular_title: L'observance du Ramadan et son retentissement sur la sécrétion gastrique.