title: [Plasma renin activity (PRA), angiotensin II (AII), atrial natriuretic peptide (ANP) and AII/ANP ratio in severely burned patients].
abstract: Plasma renin activity (PRA), angiotensin II (AII), atrial natriuretic peptide (ANP) and AII/ANP were determined by radioimmunoassay in samples of blood from 59 burn patients. The results demonstrated that PRA, AII, ANP, AII/ANP increased significantly postburn. The increased level of AII/ANP correlated positively with the extent of burn injury as well as the severity of postburn renal dysfunction suggesting that the imbalance of AII and ANP played an important role in the pathogenesis of postburn renal damage.
authors.affiliation: Burn Institute, Southwestern Hospital, Third Military Medical College.
authors.forename: D
authors.initials: D
authors.lastname: Liu
authors.forename: Z
authors.initials: Z
authors.lastname: Yang
authors.forename: A
authors.initials: A
authors.lastname: Li
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000804:Angiotensin II / Q000097:blood*; D009320:Atrial Natriuretic Factor / Q000097:blood*; D002056:Burns / Q000097:blood*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D011863:Radioimmunoassay; D012083:Renin / Q000097:blood*
chemical_list: D000804:Angiotensin II; D009320:Atrial Natriuretic Factor; D012083:Renin