Dynamic magnetic resonance imaging of the contralateral testis in patients with malignant tumor of the testis.
OBJECTIVE
Dynamic magnetic resonance imaging (MRI) was tested using a dynamic technique to evaluate the possibility of differentiating between normal contralateral testes and testes with a carcinoma in situ.


METHODS
Since March 1990, 20 volunteers and 21 patients with a malignant tumor of the testis were examined in a field strength of 1.5 Tesla (Philips Gyroscan S15) with a multislice T1-weighted fast field echo sequence before and every 63 seconds after the injection of 0.1 mmol/kg gadolinium-diethylenetriamine pentaacetic acid.


RESULTS
Significant differences (p < 0.001) in signal changes of contralateral testes were detected in dynamic MRI. This increased signal enhancement is detected even 45 months after orchiectomy in the contralateral testes. The signal increase is reduced in follow-up controls. These observations are explained by an increased perfusion which seems to be induced after a postoperative irritation, an unspecific inflammation, or postoperative bleeding.


CONCLUSIONS
To avoid false-positive diagnoses of tumors or carcinomata in situ in contralateral testes, these increased enhancements caused by postoperative reactions have to be kept in mind.
Reinges
M H
MH
Radiologische Klinik, Universität Bonn, Bonn, Germany.
Kaiser
W A
WA
Miersch
W D
WD
Vogel
J
J
D000328:Adult; D002278:Carcinoma in Situ / Q000175:diagnosis* / Q000601:surgery; D003287:Contrast Media; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D009942:Organometallic Compounds / Q000494:pharmacology; D004369:Pentetic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D011184:Postoperative Period; D012815:Signal Processing, Computer-Assisted; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000601:surgery; D013737:Testis / Q000033:anatomy & histology* / Q000187:drug effects; D013997:Time Factors
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA