[Effects of guifu dihuang pills extract on rabbit IgG accelerated mouse nephritis induced by nephrotoxic serum].
The effects of Guifu Dihuang Pills extract were observed in rabbit IgG accelerated mouse nephritis model induced by nephrotoxic serum. The results showed that this preparation could increase serum albumin, reduce urine protein, serum urea nitrogen and total cholesterol in serum, and improve the histological lesions in kidneys. The effects of Guifu Dihuang Pills extract in dosages of 0.3g/kg and 1.2g/kg were similar to those of cyclophosphamide 0.015g/kg.
Xiong
Y L
YL
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.
Wang
J H
JH
Zong
G Z
GZ
Tu
G R
GR
Feng
Q R
QR
He
W
W
Cai
H B
HB
Yu
J G
JG
Hui
L Q
LQ
D000818:Animals; D001806:Blood Urea Nitrogen; D002784:Cholesterol / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005921:Glomerulonephritis / Q000188:drug therapy* / Q000378:metabolism; D007074:Immunoglobulin G / Q000276:immunology; D007668:Kidney / Q000473:pathology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011507:Proteinuria / Q000188:drug therapy; D011817:Rabbits; D012709:Serum Albumin / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D007074:Immunoglobulin G; D012709:Serum Albumin; D002784:Cholesterol