title: [Microangiopathic hemolytic anemia associated with neoplasms: an analysis of 5 cases and a review of the literature].
abstract: From January of 1990 to June of 1993 a diagnosis of microangiopathic hemolytic anemia (MHA) was made in 5 out off 121 new patients with malignant tumor. There were 3 females and 2 males, with a mean age of 57 yr (range: 43-75), and a primary tumor in stomach (n = 2), pancreas (n = 1) and of unknown origin (n = 2). In all cases histologic type was adenocarcinoma and diagnosis was obtained by marrow examination. Four patients developed a disseminated intravascular coagulation syndrome. Intravascular deposits of fibrin, intimal proliferation and tumoral microembolisms were noted in 2 cases. Patients did not received chemotherapy, and the median survival was 7 days (range: 3-61).
authors.affiliation: Servicio de Medicina Interna, Hospital Central de Asturias (Centro Universitario), Oviedo.
authors.forename: R
authors.initials: R
authors.lastname: Susano
authors.forename: L
authors.initials: L
authors.lastname: Caminal
authors.forename: J
authors.initials: J
authors.lastname: Ferro
authors.forename: A
authors.initials: A
authors.lastname: Rubiales
authors.forename: J
authors.initials: J
authors.lastname: de Lera
authors.forename: J F
authors.initials: JF
authors.lastname: de Quirós
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000473:pathology; D000328:Adult; D000368:Aged; D000743:Anemia, Hemolytic / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009382:Neoplasms, Unknown Primary / Q000150:complications* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology
vernacular_title: Anemia hemolítica microangiopática asociada a neoplasias: análisis de cinco casos y revisión de la literatura.