title: Imaging findings in spinal neuroarthropathy.
abstract: METHODS
  The literature is reviewed and five case reports are presented.
  
  
  OBJECTIVE
  The objective was to review and emphasize the characteristic magnetic resonance imaging and radiologic findings.
  
  
  BACKGROUND
  Spinal neuroarthropathy is a destructive process involving the disc space, the adjoining vertebral bodies, and the facet joints that can be induced by traumatic paralysis as well as tabes dorsalis, syringomyelia, and diabetes mellitus.
  
  
  METHODS
  Five cases of neuropathic spine in two patients with quadriplegia and three patients with paraplegia from the authors' spinal cord unit were reviewed.
  
  
  RESULTS
  On plain radiographs and computed tomography scans, the findings of neuropathic spine were similar to those of disc space infection, severe degenerative disease, and skeletal metastasis. Magnetic resonance imaging, however, showed characteristic hypointensity of signal on T1- and T2-weighted images, which makes it possible to differentiate neuropathic spine and infection.
  
  
  CONCLUSIONS
  In neuropathic spine, neuropathic destructive changes in the vertebral bodies lead to fracture, followed by additional changes, including bone sclerosis, large osteophytes, and loss of disc space. A large paraspinal mass develops because of improper fracture healing. At the end stage of this process, a pseudarthrosis may form, as was evident in three of the five patients reviewed.
authors.affiliation: Department of Radiology, University of California, San Diego Medical Center.
authors.forename: Y H
authors.initials: YH
authors.lastname: Park
authors.forename: J A
authors.initials: JA
authors.lastname: Taylor
authors.forename: S M
authors.initials: SM
authors.lastname: Szollar
authors.forename: D
authors.initials: D
authors.lastname: Resnick
mesh_terms: D000328:Adult; D001177:Arthropathy, Neurogenic / Q000175:diagnosis* / Q000209:etiology; D017102:Fracture Healing; D005598:Fractures, Spontaneous / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010264:Paraplegia / Q000150:complications; D011542:Pseudarthrosis / Q000175:diagnosis / Q000209:etiology; D011782:Quadriplegia / Q000150:complications; D013122:Spinal Diseases / Q000175:diagnosis* / Q000209:etiology; D016103:Spinal Fractures / Q000175:diagnosis / Q000209:etiology