title: A prospective study of weight maintenance in obese subjects reduced to normal body weight without weight-loss training.
abstract: We examined the pattern of weight maintenance in 24 obese women [body mass index (BMI; in kg/m2) 27.6 +/- 0.4 who were provided foods for a balanced deficit diet until each had lost > or = 10 kg and attained normal body weight (BMI 22.9 +/- 0.4). At 1 y subjects had regained a mean of 42% of their weight loss, which increased to 87% at 4 y. At 4 y 44% of patients had regained < 75%, whereas 37% had regained > or = 100% of the weight originally lost. The amount of weight gained was markedly different from that observed in 24 pair-matched never-obese control subjects over the same length of follow-up. Because the results reported herein were obtained without teaching the subjects weight-control skills, they may be regarded as reflective of the natural history of weight maintenance in this population and may serve as a reference for various weight-intervention programs. The pattern of weight rebound observed in this study is very similar to the pattern observed in combined results from published diet and behavioral-modification programs, which raises important questions regarding the efficacy of these approaches in long-term weight maintenance.
authors.affiliation: Department of Nutrition Sciences, University of Alabama at Birmingham.
authors.forename: D D
authors.initials: DD
authors.lastname: Hensrud
authors.forename: R L
authors.initials: RL
authors.lastname: Weinsier
authors.forename: B E
authors.initials: BE
authors.lastname: Darnell
authors.forename: G R
authors.initials: GR
authors.lastname: Hunter
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001823:Body Composition; D001835:Body Weight; D016022:Case-Control Studies; D015928:Cognitive Behavioral Therapy; D015444:Exercise; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology* / Q000628:therapy; D011446:Prospective Studies; D015430:Weight Gain; D015431:Weight Loss