title: [Clinical evaluation of biapenem (L-627) in children].
abstract: Biapenem (L-627) was evaluated for its efficacy and safety. The following results were obtained. L-627 was given to 9 patients with infections: 3 with pneumonia, 1 with acute bronchopneumonia, 1 with acute bronchitis, 1 with bacteremia, 1 with tonsillitis, 2 with exceptional case. Therapeutic responses were excellent in 3, good in 4, with an efficacy rate of 100%. Adverse reactions were noted. No abnormalities were shown in laboratory data. It has been concluded that L-627 is a useful drug for the treatment of bacterial infections in children.
authors.affiliation: Department of Pediatrics, Sapporo City General Hospital.
authors.forename: N
authors.initials: N
authors.lastname: Fukushima
authors.forename: A
authors.initials: A
authors.lastname: Ishikawa
authors.forename: A
authors.initials: A
authors.lastname: Takase
authors.forename: Y
authors.initials: Y
authors.lastname: Wagatsuma
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011014:Pneumonia / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy; D013845:Thienamycins / Q000627:therapeutic use*
chemical_list: D013845:Thienamycins; C065257:biapenem