A water-soluble 1,2-diaminocyclohexaneplatinum(II) complex containing procaine hydrochloride: synthesis and antiproliferative activity in vitro.
Cafaggi
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Istituto di Analisi e Tecnologie Farmaceutiche ed Alimentari dell'Università di Genova, Italy.
Esposito
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D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001806:Blood Urea Nitrogen; D004273:DNA, Neoplasm / Q000096:biosynthesis; D005260:Female; D007941:Leukemia P388 / Q000188:drug therapy / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D009944:Organoplatinum Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D011343:Procaine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D009944:Organoplatinum Compounds; C089541:procaine-chloro-1,2-diaminocyclohexaneplatinum(II); D011343:Procaine; D013936:Thymidine