title: Transcranial Doppler sonography in craniosynostosis.
abstract: In the management of craniosynostosis, there is a need for quantitative assessment of treatment methods and outcome. Radiology and pressure studies are well documented, but so far little attention has been given to cerebral blood flow changes and their possible relevance. This paper reports our initial experience using transcranial Doppler sonography to calculate the cerebrovascular resistance and cerebral blood velocities in the major basal vessels before and after surgery for craniosynostosis. Ten patients were studied using the Scimed 2-MHz probe through the temporal and frontal "windows" of the skull. Measurements were taken under standard physiological conditions before, during and after surgery. Preliminary results suggest that this non-invasive technique may be helpful in predicting and assessing the outcome following surgery for craniosynostosis.
authors.affiliation: Department of Craniofacial Surgery, Queen Elizabeth Hospital, Birmingham, UK.
authors.forename: J B
authors.initials: JB
authors.lastname: Iqbal
authors.forename: A D
authors.initials: AD
authors.lastname: Hockley
authors.forename: M J
authors.initials: MJ
authors.lastname: Wake
authors.forename: J H
authors.initials: JH
authors.lastname: Goldin
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D001921:Brain / Q000098:blood supply*; D002675:Child, Preschool; D003398:Craniosynostoses / Q000000981:diagnostic imaging* / Q000601:surgery; D004867:Equipment Design; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011673:Pulsatile Flow / Q000502:physiology; D016896:Treatment Outcome; D017585:Ultrasonography, Doppler, Transcranial / Q000295:instrumentation*; D014655:Vascular Resistance / Q000502:physiology