[The treatment of scabies with oral ivermectin].
To evaluate the efficacy and safety of a single 200 mcg/Kg dose of ivermectine as compared with placebo in the treatment of scabies was settled. Fifty five patients with the diagnosis of scabies were randomized to a single oral dose of ivermectine or placebo. The study informed that 26 (79.3%) patients were cured with ivermectine on their first follow-up visit, as compared to only four (16%) in the placebo group (X2 = 77.07, p < 0.001). Overall, 37 of 50 (74%) patients treated with ivermectine cured, as compared to only four of 26 (16%) treated with placebo, this difference was still significant (X2 = 23.66, p < 0.001). We concluded that ivermectine is a safe and effective treatment for scabies.
Macotela-Ruíz
E
E
Servicio de Dermatología y Micología médica, Hospital de Especialidades. Centro Médico Nacional Siglo XXI, IMSS, México, D.F.
Peña-González
G
G
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D016009:Chi-Square Distribution; D002648:Child; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D010919:Placebos; D012532:Scabies / Q000188:drug therapy* / Q000453:epidemiology
D010919:Placebos; D007559:Ivermectin
Tratamiento de la escabiasis con ivermectina por vía oral.