title: Analysis of ACE inhibitor drugs by high performance liquid chromatography.
abstract: Seven angiotensin-converting-enzyme (ACE) inhibitors have been analyzed by HPLC. The influence of different organic modifiers and counter-ions in the eluent at different pH values have been investigated allowing the identification of the best experimental conditions for the analysis of these compounds. The sinergic effect of TEA and propanol in the eluents resulted as a critical factor to obtain satisfactory peak shapes and resolution.
authors.affiliation: Dipartimento di Chimica Farmaceutica e Tossicologica, Facoltà di Farmacia Università di Napoli, Federico II, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Barbato
authors.forename: P
authors.initials: P
authors.lastname: Morrica
authors.forename: F
authors.initials: F
authors.lastname: Quaglia
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors