[An preliminary study on hepato-protective action of seed oil of Hippophae rhamnoides L. (HR) and mechanism of the action].
The seed oil of Hippophae rhamnoides markedly inhibits the rise of MDA in liver of mice and rats induced by CCl4, AAP and ethyl alcohol, decreases significantly the activity of SGPT and SGOT, and markedly checks the depletion of GSH in liver of mice induced by AAP. The microscopic and electron-microscopic examination has shown that the seed oil can lighten liver injury.
Cheng
T J
TJ
Lanzhou Medical College.
Pu
J K
JK
Wu
L W
LW
Ma
Z R
ZR
Cao
Z
Z
Li
T J
TJ
D000082:Acetaminophen; D000818:Animals; D002252:Carbon Tetrachloride Poisoning; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism / Q000473:pathology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D008297:Male; D051379:Mice; D008930:Mitochondria, Liver / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal; D000082:Acetaminophen