Variable susceptibility of Lewis rats to experimental autoimmune encephalomyelitis.
This report is to alert other investigators that Lewis rats, which are widely employed in studies of autoimmune diseases, vary considerably with respect to susceptibility to experimental autoimmune encephalomyelitis (EAE), depending upon commercial source.
Gould
K E
KE
Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, MI 48201.
Stepaniak
J A
JA
Swanborg
R H
RH
D000818:Animals; D004198:Disease Susceptibility; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000209:etiology*; D051381:Rats; D011917:Rats, Inbred Lew / Q000502:physiology*