Treatment of chronic neutropenia with chloramphenicol.
We describe a patient with chronic congenital idiopathic neutropenia whose neutropenia resolved on four occasions during chloramphenicol therapy. This is the second report of chloramphenicol-responsive chronic neutropenia. Chloramphenicol, in addition to its antimicrobial action, has immune-modulating activity, which may explain the reversal of neutropenia.
Feder
H M
HM
Department of Family Medicine, University of Connecticut Health Center, Farmington 06030-3960.
Bergstrom
S K
SK
D002648:Child; D002701:Chloramphenicol / Q000627:therapeutic use*; D002908:Chronic Disease; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000151:congenital / Q000188:drug therapy*
D002701:Chloramphenicol