Flow-through photometric sensor for determination of sulfonamides.
A sensor based on integration of spectrophotometric detection and retention of the product of the Bratton-Marshall reaction for the determination of sulfanilamide, sulfamethazine, sulfaquinoxaline and sulfathiazole is reported. The methods developed using this sensor in a flow injection manifold feature linear ranges for these analytes between 10 and 1200 ng ml(-1) with relative standard deviations smaller than 2.6% in all instances and they were applied to the determination of sulfonamides in spiked milk and water samples with excellent results. The two main advantages of these sensor-based methods over other automated and non-automated counterparts are enhanced sensitivity as a result of in situ concentration and avoidance of using a de-bubbler to eliminate the nitrogen produced in the flowing system.
Tena
M T
MT
Department of Analytical Chemistry, Faculty of Sciences, University of Cordoba, Spain.
Luque de Castro
M D
MD
Valcárcel
M
M
D000818:Animals; D008892:Milk / Q000737:chemistry*; D010783:Photometry; D013449:Sulfonamides / Q000032:analysis*
D013449:Sulfonamides