title: The distribution of G (VP7) and P (VP4) serotypes among human rotaviruses recovered from Japanese children with diarrhea.
abstract: Both the G (VP7) and P (VP4) serotypes of human rotaviruses collected over a 10-year period from Japanese children with diarrhea were determined by recently-developed polymerase chain reaction-based typing assays. The combination of G1 and P8 was found in 65.2% and the combination of G2 and P4 was found in 15.2%. For the rest of the specimens, only a few other combinations occurred and their relative frequencies were less than 10%. The viruses carrying P9 were always associated with G3 as is the prototype strain AU-1.
authors.affiliation: Department of Microbiology, Akita University School of Medicine, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Kaga
authors.forename: M
authors.initials: M
authors.lastname: Iizuka
authors.forename: T
authors.initials: T
authors.lastname: Nakagomi
authors.forename: O
authors.initials: O
authors.lastname: Nakagomi
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D002213:Capsid / Q000032:analysis* / Q000276:immunology; D036022:Capsid Proteins; D002675:Child, Preschool; D003967:Diarrhea / Q000821:virology*; D004591:Electrophoresis, Polyacrylamide Gel; D005243:Feces; D006801:Humans; D007564:Japan; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000032:analysis; D012401:Rotavirus / Q000145:classification* / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000821:virology*; D012703:Serotyping
chemical_list: D000956:Antigens, Viral; D036022:Capsid Proteins; D012367:RNA, Viral; C060339:VP4 protein, Rotavirus; C050779:VP7 protein, Rotavirus