title: Investigations on the synthesis and properties of N-aryl (heteroaryl) piperazinylalkyl derivatives of imide of 6-methyl-2-(1-piperidino)-3,4-pyridinedicarboxylic acid.
abstract: The synthesis of N-aryl(heteroaryl)piperazinylalkyl derivatives of imide of 2-(1-piperidino)-3,4-pyridinedicarboxylic acid is reported. 3 examined compounds proved to be active pharmacologically in some tests.
authors.affiliation: Department of Chemistry of Drugs, School of Medicine, Wroclaw, Poland.
authors.forename: H
authors.initials: H
authors.lastname: Sladowska
authors.forename: M
authors.initials: M
authors.lastname: Sieklucka-Dziuba
authors.forename: M
authors.initials: M
authors.lastname: Misztal
authors.forename: Z
authors.initials: Z
authors.lastname: Kleinrok
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D014151:Anti-Anxiety Agents / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D013329:Structure-Activity Relationship
chemical_list: D000700:Analgesics; D014151:Anti-Anxiety Agents; D000927:Anticonvulsants