title: Structural elucidation of two novel ergot alkaloid impurities in alpha-ergokryptine and bromokryptine.
abstract: Two novel natural derivatives (2 and 3) of the ergot alkaloid alpha-ergokryptine (1), as well as their synthetically brominated analogues (5 and 6) were isolated and identified by NMR and MS methods. Compounds 2 and 5 contain what appears to be a so far unknown natural amino acid building block. Complete 1H and 13C NMR assignments are given for compounds 1-6.
authors.affiliation: Chemical Works of Gedeon Richter Ltd., Budapest, Hungary.
authors.forename: C
authors.initials: C
authors.lastname: Szántay
authors.forename: M
authors.initials: M
authors.lastname: Bihari
authors.forename: J
authors.initials: J
authors.lastname: Brlik
authors.forename: A
authors.initials: A
authors.lastname: Csehi
authors.forename: A
authors.initials: A
authors.lastname: Kassai
authors.forename: A
authors.initials: A
authors.lastname: Aranyi
mesh_terms: D001971:Bromocriptine / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004340:Drug Contamination; D004873:Ergolines / Q000032:analysis*; D004876:Ergot Alkaloids / Q000032:analysis* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
chemical_list: D004873:Ergolines; D004876:Ergot Alkaloids; D001971:Bromocriptine; C100269:ergocryptine