Meckel's diverticulum: possible detection by combining pentagastrin with histamine H2 receptor blocker.
A Meckel's scan was performed on a 7-yr-old boy because of rectal bleeding. He was premedicated with pentagastrin (6 micrograms/kg subcutaneously) followed by 259 MBq (7 mCi) [99mTc]pertechnetate intravenously. The study was essentially negative. Because of persistent rectal bleeding and a strong clinical suspicion of a Meckel's, a repeat study was performed 6 wk later. He received pentagastrin as before, but this time was also given a histamine H2 receptor blocker (zantac). A Meckel's diverticulum was clearly evident.
Heyman
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Division of Nuclear Medicine, Children's Hospital of Philadelphia, PA 19104.
D002648:Child; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D008297:Male; D008467:Meckel Diverticulum / Q000150:complications / Q000000981:diagnostic imaging*; D010418:Pentagastrin; D011292:Premedication; D011877:Radionuclide Imaging; D011899:Ranitidine; D012007:Rectum; D012680:Sensitivity and Specificity; D013670:Sodium Pertechnetate Tc 99m
D011899:Ranitidine; D013670:Sodium Pertechnetate Tc 99m; D010418:Pentagastrin