title: Two cases of amiodarone-induced thyrotoxicosis successfully treated with a short course of antithyroid drugs while amiodarone was continued.
abstract: Two patients with amiodarone-induced thyrotoxicosis were treated successfully with potassium perchlorate and carbimazole while treatment with amiodarone was continued. These antithyroid drugs were stopped after the patients had became clinically and biochemically euthyroid. During follow up, when treatment with amiodarone continued, thyrotoxicosis did not recur. Amiodarone-induced thyrotoxicosis seems to be a transient condition that can be treated successfully with a short course of antithyroid drugs without stopping amiodarone treatment.
authors.affiliation: Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: M D
authors.initials: MD
authors.lastname: Trip
authors.forename: D R
authors.initials: DR
authors.lastname: Düren
authors.forename: W M
authors.initials: WM
authors.lastname: Wiersinga
mesh_terms: D000293:Adolescent; D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D002231:Carbimazole / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010472:Perchlorates / Q000627:therapeutic use*; D017680:Potassium Compounds / Q000627:therapeutic use*; D013610:Tachycardia / Q000188:drug therapy; D013971:Thyrotoxicosis / Q000139:chemically induced* / Q000188:drug therapy
chemical_list: D010472:Perchlorates; D017680:Potassium Compounds; C009006:potassium perchlorate; D002231:Carbimazole; D000638:Amiodarone