[Clinicopathologic correlation in 50 cases of acquired immunodeficiency syndrome. Retrospective study].
OBJECTIVE
To analyze myocardial abnormalities in patients of acquired immunodeficiency syndrome with clinical and pathological correlation.


METHODS
We selected 50 cases, retrospectively, age ranged from 3 months to 40 years, all of them had myocardial changes and the data of clinical records fulfilled our protocol. Cases of others cardiac diseases were not included.


RESULTS
The pathological findings were: myocarditis in 33 (11 had severe myocarditis) and degenerative hystological lesions in 17. The etiologic agents detected were: Toxoplasma in 11, Cryptococcus in 7 and Cytomegalovirus in 3. In 12 cases we could not find any agent. In 15 cases occurred others lesions: endocarditis, pericarditis and sarcoma of Kaposi. It was noted tachycardia in 15 cases, decrease of heart sounds in 12, arterial hypotension in seven, systolic murmur in 8, galop rhythm in 7, pericardial friction rub in 3, arrhythmia in 2. Four patients had congestive heart failure. The EKG showed sinus tachycardia in 18, ST and T changes in 10, low voltage in 5, ST segment elevation in 5 and extrasystoles in 3 cases. The echocardiogram findings were: pericardial effusion in 9 cases and 9 had ventricular dysfunction.


CONCLUSIONS
The cardiac lesions were very important even in patients without clinical signals. We need others prospective studies with viral identification trying to detect specific lesions of HIV.
Herdy
G V
GV
Hospital Antônio Pedro, UFF, Niterói, RJ.
Ramos
R
R
Bazin
A R
AR
Herdy
A H
AH
Almeida
P S
PS
Ramos
R G
RG
Carrinho
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000382:microbiology / Q000469:parasitology / Q000473:pathology* / Q000821:virology; D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003454:Cryptococcus / Q000302:isolation & purification; D003587:Cytomegalovirus / Q000302:isolation & purification; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009205:Myocarditis / Q000382:microbiology / Q000469:parasitology / Q000473:pathology* / Q000821:virology; D009206:Myocardium / Q000473:pathology; D012189:Retrospective Studies; D014122:Toxoplasma / Q000302:isolation & purification
Correlação clínicopatológica de 50 casos de síndrome de imunodeficência adquirida. Estudo retrospectivo.