title: Prognostic variables in patients with gastrointestinal carcinoid tumours.
abstract: Prognostic variables in patients with gastrointestinal carcinoid tumour were studied with a view to identifying those most likely to benefit from aggressive therapy. A total of 188 patients were studied; the median follow-up of those surviving was 72 months. On univariate analysis variables of prognostic significance were sex (P < 0.01), site of the primary tumour (P < 0.01), depth of invasion (P < 0.001), tumour size (P < 0.005), presence of lymph node (P < 0.001) or liver (P < 0.001) metastases, mode of discovery (P < 0.001) and operative intent (P < 0.001). On multivariate analysis the variables independently predictive of death from disease were sex (women have a better prognosis) and presence of metastases at the time of diagnosis.
authors.affiliation: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York.
authors.forename: E W
authors.initials: EW
authors.lastname: McDermott
authors.forename: B
authors.initials: B
authors.lastname: Guduric
authors.forename: M F
authors.initials: MF
authors.lastname: Brennan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002276:Carcinoid Tumor / Q000401:mortality* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005770:Gastrointestinal Neoplasms / Q000401:mortality* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D011379:Prognosis; D012189:Retrospective Studies; D012737:Sex Factors; D016019:Survival Analysis