The frequency of antisperm antibodies in the cervical mucus of women with poor postcoital tests and their effect on pregnancy rates.
OBJECTIVE
To determine the impact of the presence of antisperm antibodies (ASAs) in the cervical mucus of female partners in couples with unexplained poor postcoital tests (PCT). Furthermore, the efficacy of intrauterine insemination (IUI) in these same patients was determined by pregnancy rates (PRs).


METHODS
Pregnancy rates following IUI in patients with infertility and poor postcoital tests, whether the cervical mucus was positive or negative for ASAs, were evaluated.


RESULTS
The 6-month PRs were similar in the ASA negative (40.5%) versus the positive (42.4%) group.


CONCLUSIONS
It appears that the antifertility effect of ASA may be mainly the immobilization of sperm in the cervical mucus, and thus, performing IUI may effectively correct the problem.
Check
J H
JH
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden.
Bollendorf
A
A
Katsoff
D
D
Kozak
J
J
D000906:Antibodies / Q000276:immunology*; D002582:Cervix Mucus / Q000276:immunology*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D007246:Infertility / Q000276:immunology*; D007315:Insemination, Artificial / Q000276:immunology; D015993:Life Tables; D008297:Male; D013094:Spermatozoa / Q000276:immunology*
D000906:Antibodies