title: Discordance between direct and PHA-stimulated chromosome preparations from neonates.
abstract: Four examples of discordance between karyotypes prepared from direct and PHA-stimulated neonatal blood samples are presented. The specimens were initially studied by direct methods to establish a neonatal karyotype rapidly. The patients are described and the significance of the findings is discussed.
authors.affiliation: Department of Cytogenetics and Molecular Genetics, Women's and Children's Hospital, Adelaide, Australia.
authors.forename: I W
authors.initials: IW
authors.lastname: Garnham
authors.forename: H
authors.initials: H
authors.lastname: Fernandez
authors.forename: D F
authors.initials: DF
authors.lastname: Callen
authors.forename: E A
authors.initials: EA
authors.lastname: Haan
authors.forename: G R
authors.initials: GR
authors.lastname: Sutherland
mesh_terms: D002478:Cells, Cultured / Q000187:drug effects; D002869:Chromosome Aberrations / Q000175:diagnosis / Q000235:genetics; D025063:Chromosome Disorders; D005260:Female; D005312:Fetal Blood / Q000166:cytology*; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007621:Karyotyping / Q000379:methods*; D008297:Male; D009030:Mosaicism; D010835:Phytohemagglutinins
chemical_list: D010835:Phytohemagglutinins