title: Reward fails to alter response bias in depression.
abstract: Several different models postulate that depression is associated with decreased approach-related behavior. Relatively little has been done to date to specifically investigate this issue. In the present study, a signal-detection analysis was used to examine the response biases of dysphoric and nondysphoric female undergraduates during 3 payoff conditions: neutral, reward, and punishment. As predicted, the dysphoric subjects had a smaller change in bias from the neutral to the reward condition compared with the nondysphoric group. The 2 groups did not differ during the neutral and punishment conditions. These findings are consistent with the hypothesis that the left frontal hypoactivation observed in depression reflects a deficit in approach-related behavior.
authors.affiliation: Department of Psychology, University of Wisconsin-Madison 53706.
authors.forename: J B
authors.initials: JB
authors.lastname: Henriques
authors.forename: J M
authors.initials: JM
authors.lastname: Glowacki
authors.forename: R J
authors.initials: RJ
authors.lastname: Davidson
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D010775:Photic Stimulation; D010865:Pilot Projects; D011930:Reaction Time; D012201:Reward