[Magnetic resonance imaging in denervated muscle. A preliminary study].
Ten patients with various forms of peripheral neuropathy and spinal radiculopathy were examined with MRI using a low-field permanent magnet (0.2 T) and spin echo (SE)/inversion recovery (IR) sequences, with an adequate inversion time to suppress healthy muscle signal. In acute denervation MR sensitivity was low on both sequences; in subacute denervation the damaged muscle was more intense than the healthy muscle only on IR sequences. MRI adequately depicted fatty infiltration in chronic denervation. In conclusion, MRI is a promising tool for mapping and noninvasively monitoring denervated motor units in skeletal muscles, whose role is currently complementary to that of electromyography.
Fanucci
E
E
Istituto di Radiologia, Università degli Studi di Roma Tor Vergata, IRCCS S. Lucia.
Masala
S
S
Floris
R
R
Apruzzese
A
A
Gagliarducci
L
L
Orlacchio
A
A
Iani
C
C
Simonetti
G
G
D000208:Acute Disease; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D009132:Muscles / Q000294:innervation* / Q000473:pathology*; D009468:Neuromuscular Diseases / Q000175:diagnosis; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis; D013126:Spinal Nerve Roots / Q000473:pathology
Imaging con risonanza magnetica nel muscolo denervato. Studio preliminare.