title: Axon ramification following unilateral cortical ablation in neonatal rats.
abstract: We confirmed the formation of an aberrant ipsilateral corticospinal tract after unilateral cerebral cortical ablation during the neonatal period in rat. This tract was studied using anterograde horseradish peroxidase (HRP) tracing. Ramifications of the axons in the pyramidal tract were found to contribute to the ipsilateral tract at the level of the pyramidal decussation, suggesting that ramification of immature axons play an important role in the formation of the ipsilateral corticospinal tract.
authors.affiliation: Department of Pediatrics, Shiga University of Medical Science, Ohtsu, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ono
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: C
authors.initials: C
authors.lastname: Ishizuka
authors.forename: J
authors.initials: J
authors.lastname: Uematsu
authors.forename: A
authors.initials: A
authors.lastname: Aisaka
authors.forename: T
authors.initials: T
authors.lastname: Yamano
authors.forename: M
authors.initials: M
authors.lastname: Shimada
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001369:Axons / Q000648:ultrastructure*; D002540:Cerebral Cortex / Q000502:physiology / Q000648:ultrastructure*; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D009412:Nerve Fibers / Q000648:ultrastructure; D009434:Neural Pathways / Q000166:cytology / Q000648:ultrastructure; D017966:Pyramidal Cells / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000166:cytology / Q000648:ultrastructure
chemical_list: D006735:Horseradish Peroxidase