Gerontology. Mutation, variation and the evolution of ageing.
A recent experiment provides evidence that ageing is partly due to mutations with deleterious effects late in life that have been retained in the population as selection against them is weak.
Partridge
L
L
Department of Genetics and Biometry, University College London, UK.
Prowse
N
N
D000368:Aged; D000375:Aging / Q000235:genetics*; D000818:Animals; D005075:Biological Evolution; D005260:Female; D014644:Genetic Variation; D005853:Geriatrics; D006801:Humans; D008297:Male; D009154:Mutation; D012641:Selection, Genetic