A modified technique for nerve-sparing retroperitoneal lymph node dissection in stage II nonseminomatous germ cell tumors using intraoperative measurement of bladder neck pressure alterations following sympathetic nerve fiber electrostimulation.
We present a simplified method for nerve-sparing retroperitoneal lymph node dissection in patients with nonseminomatous testicular cancer. The sympathetic fibers involved in antegrade ejaculation are identified by intraoperative electrostimulation, resulting in an increase of bladder neck closure pressure. This increase is demonstrated by intraoperative monitoring of both the intravesical pressure and the pressure within the bladder neck by a two-channel microtip measuring catheter. 4 patients with stage I and 6 patients with stage II nonseminomatous testicular cancer were operated on with this modified technique. Ejaculation was preserved in all cases. Semen volume ranged from 2.2 to 4.0 ml. Sperm cell count ranged from 2 to 22 x 10(6)/ml with 20-50% motile spermatozoa, except for 2 of the 3 patients who initially presented with preoperative azoospermia following chemotherapy. In 1 of these 3 patients, postoperative semen analyses revealed a recovery of germ cell function demonstrated by oligoasthenozoospermia.
Weidner
W
W
Department of Urology, University of Göttingen, FRG.
Zöller
G
G
Sauerwein
D
D
Fischer
C
C
Hummel
G
G
Kallerhoff
M
M
Ringert
R H
RH
D000320:Adrenergic Fibers / Q000502:physiology*; D000328:Adult; D017024:Chemotherapy, Adjuvant; D004542:Ejaculation / Q000502:physiology; D004558:Electric Stimulation; D018237:Germinoma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007248:Infertility, Male / Q000517:prevention & control*; D008197:Lymph Node Excision / Q000379:methods*; D008297:Male; D016343:Monitoring, Intraoperative / Q000379:methods*; D009367:Neoplasm Staging; D011312:Pressure; D012187:Retroperitoneal Space; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery*; D001743:Urinary Bladder / Q000294:innervation / Q000502:physiology*