A regulatory and industrial perspective of the use of carbon-14 and tritium isotopes in human ADME studies.
Dain
J G
JG
Department of Drug Metabolism and Pharmacokinetics, Sandoz Pharmaceuticals Corporation, E. Hanover, New Jersey 07936.
Collins
J M
JM
Robinson
W T
WT
D000293:Adolescent; D000328:Adult; D002250:Carbon Radioisotopes; D004345:Drug Industry / Q000639:trends*; D005260:Female; D006801:Humans; D007880:Legislation, Drug / Q000639:trends*; D008297:Male; D014316:Tritium; D014481:United States; D014486:United States Food and Drug Administration
D002250:Carbon Radioisotopes; D014316:Tritium