title: A low flip angle spin-echo technique for producing rapid diffusion weighted MR images.
abstract: A method is described for producing rapid diffusion-weighted images using a modified low flip angle imaging technique. Utility of the method is demonstrated by the quantification of diffusion coefficients in a rat model of focal ischemia. The method may be readily applied to animal research studies using NMR research systems with modest gradient capabilities.
authors.affiliation: NIH Center for Stroke Research, Department of Neurology, Henry Ford Health Sciences Center, Detroit, MI 48202.
authors.forename: R J
authors.initials: RJ
authors.lastname: Ordidge
authors.forename: R A
authors.initials: RA
authors.lastname: Knight
authors.forename: J A
authors.initials: JA
authors.lastname: Helpern
authors.forename: J W
authors.initials: JW
authors.lastname: Hugg
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000473:pathology; D004058:Diffusion; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012815:Signal Processing, Computer-Assisted