title: [Expectant management of premature rupture of fetal membranes before completion of the 35th week of pregnancy--retrospective analysis of 44 cases].
abstract: 44 cases of preterm premature rupture of fetal membranes (PPROM) before 35 completed weeks of gestation were analyzed retrospectively. Expectative management was based on infection diagnosis, vaginal disinfection and in case of signs of infection on systemic antibiotic therapy. Glucocorticoids for induction of lung maturity were generally administered. Perinatal mortality was 11.4%, after exclusion of one congenital anomaly 9.3% respectively. Lung immaturity was the main cause of neonatal death. Only 5 neonates developed clinical infection, with 4 of these showing prepartal maternal signs of infection. Maternal signs of infection are not a specific signal for later neonatal infection. Cerebral bleeding complications and pathological neurologic status occurred in 10/39 and 8/39 cases respectively. Cesarean section rate amounted to 15/44 (34%).
authors.affiliation: Frauenklinik, Universität Rostock.
authors.forename: H
authors.initials: H
authors.lastname: Müller
authors.forename: V
authors.initials: V
authors.lastname: Briese
authors.forename: H
authors.initials: H
authors.lastname: Nagel
mesh_terms: D000293:Adolescent; D000328:Adult; D016470:Bacteremia / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D002423:Cause of Death; D002821:Chorioamnionitis / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005322:Premature Rupture of Fetal Membranes / Q000628:therapy*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011272:Pregnancy, Multiple; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors
vernacular_title: Exspektatives Management des vorzeitigen Blasensprungs vor der vollendeten 35. Schwangerschaftswoche--retrospektive Analyse von 44 Fällen.