[Hepatitis C and chronic alcoholic hepatopathy].
We evaluated hepatitis C virus prevalence in 105 patients with chronic alcoholic liver disease by research of antibodies to hepatitis C virus (anti-HCV) by second generation recombinant based enzyme immunosorbent to assay and immunoblot to assay. 46 patients of 105 (43.7%) were anti-HCV positive: 2 in steatosis group (9.5%), 3 in steatofibrosis (23%), 10 in chronic active hepatitis (66.6%), 22 in cirrhosis (59.4%) and 9 in hepatocellular carcinoma (47.3%). These patients had higher levels of serum gammaglobulin and transaminases than seronegative patients. We think that there is a correlation between high prevalence of antibodies anti-HCV and the evolution of damage in chronic alcoholic liver disease.
Pagani
A
A
Divisione di Medicina Generale 2, USSL 34, Presidio Ospedaliero di Rovato, Brescia.
Sala
N
N
Zigliani
P
P
Galante
T
T
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D016009:Chi-Square Distribution; D002908:Chronic Disease; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006508:Hepatitis Antibodies / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008099:Liver / Q000473:pathology; D008108:Liver Diseases, Alcoholic / Q000453:epidemiology / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies
D006508:Hepatitis Antibodies
Epatite C ed epatopatia cronica alcolica.