A new administration form of the nasal decongestant oxymetazoline: a study on the change of ostial patency in healthy individuals.
A new administration form of the nasal decongestant oxymetazoline and the effect on patency of the maxillary ostium was investigated in five healthy volunteers. Registration and comparison of the equivalent diameter after administration of placebo spray and oxymetazoline spray, placebo solution and oxymetazoline solution were performed. It is our impression that administration of solution with the new spring-bellows container compared to spray oxymetazoline, is a more effective way of increasing the equivalent diameter of the maxillary ostium.
Jannert
M
M
Department of Otorhinolaryngology, University of Lund, Malmö General Hospital, Sweden.
Fryksmark
U
U
Ackerhans
M
M
Nilson
K
K
D000280:Administration, Inhalation; D000336:Aerosols; D018592:Cross-Over Studies; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000187:drug effects* / Q000502:physiology; D009330:Nebulizers and Vaporizers; D010109:Oxymetazoline / Q000008:administration & dosage* / Q000494:pharmacology
D000336:Aerosols; D010109:Oxymetazoline