Pregnancy rates in a donor sperm program using cryopreservation: effects of total number of motile sperm inseminated and of a procedure to concentrate sperm.
OBJECTIVE
To determine the relationship between the total number of motile sperm per insemination (TMSI) and pregnancy rates in a donor insemination program. To determine the effect of sperm concentration and resultant increase of TMSI on pregnancy rates.


METHODS
Retrospective analysis of pregnancy rates.


METHODS
University hospital with tertiary service.


METHODS
179 women undergoing donor insemination.


METHODS
None.


METHODS
Calculation of pregnancy rates according to TMSI.


RESULTS
The pregnancy rate with insemination of thawed donor sperm increases when the TMSI of unconcentrated sperm is > or = 80 x 10(6). Pregnancy rates with previously concentrated sperm are as good as or better than rates of unconcentrated specimens.


CONCLUSIONS
TSMI is important in determining pregnancy rates in donor insemination programs, and concentration of sperm prior to freezing may enhance pregnancy rates by increasing the TMSI.
Maier
D B
DB
Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington.
Kuslis
S S
SS
Luciano
A A
AA
D015925:Cryopreservation; D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D012661:Semen; D012662:Semen Preservation; D013076:Sperm Count; D013081:Sperm Motility