[Determination of secretory immunoglobulin A in cervicovaginal secretions of healthy women with an ELISA method].
Secretory IgA of the cervico-vaginal secretions was determined for the first time using a modified ELISA method following the recommendations of Sohl Akerlund et al. (Scand. J. Immunol. 6 [1977] 1275). The results were compared with the total protein content of the cervico-vaginal secretions, which were within the normal limits reported in literature. Women in the middle of the menstrual cycle and those taking anti-ovulants, showed lower and those during pregnancy higher values. Secretory sIgA could not be detected in vaginal secretions of hysterectomised women.
Mendling
W
W
Frauenklinik, Kliniken St. Antonius gGmbH Wuppertal.
Metzger
P
P
D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000187:drug effects / Q000276:immunology*; D003276:Contraceptives, Oral / Q000008:administration & dosage; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007071:Immunoglobulin A, Secretory / Q000032:analysis*; D008597:Menstrual Cycle / Q000187:drug effects / Q000276:immunology; D008875:Middle Aged; D011247:Pregnancy; D012016:Reference Values; D014621:Vagina / Q000187:drug effects / Q000276:immunology*
D003276:Contraceptives, Oral; D007071:Immunoglobulin A, Secretory
Bestimmung des sekretorischen Immunoglobulin A im Zervikovaginalsekret gesunder Frauen mit einer ELISA-Methode.