[Autoantibodies against a 58 kD protein in neutropenia and NK cell deficiency].
An autoantibody against a 58 kD protein on granulocytes, activated NK cells and a subpopulation of B cells was detected in a patient with neutropenia and NK cell deficiency. The patient suffered from recurrent mucocutaneous candidosis and pharyngitis. After 18 months, a spontaneous remission of neutropenia and NK cell deficiency was observed, the autoantibody disappeared from the serum.
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Abteilung für Immunologie und Transfusionsmedizin, Medizinischen Hochschule Hannover.
Bode
F M
FM
Schmidt
R E
RE
D000328:Adult; D000954:Antigens, Surface / Q000737:chemistry* / Q000276:immunology; D001323:Autoantibodies / Q000276:immunology*; D001324:Autoantigens / Q000737:chemistry; D001327:Autoimmune Diseases / Q000276:immunology*; D016175:B-Lymphocyte Subsets / Q000276:immunology; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000276:immunology*; D007694:Killer Cells, Natural / Q000276:immunology*; D008970:Molecular Weight; D009503:Neutropenia / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology
D000954:Antigens, Surface; D001323:Autoantibodies; D001324:Autoantigens
Autoantikörper gegen ein 58-kD-Protein bei Neutropenie und NK-Zell-Defizienz.