title: A model-based simulator for testing rule-based decision support systems for mechanical ventilation of ARDS patients.
abstract: A model-based simulator was developed for testing rule-based decision support systems that manages ventilator therapy of patients with the Adult Respiratory Distress Syndrome (ARDS). The simulator is based on a multi-compartment model of the human body and mathematical models of the gas exchange abnormalities associated with ARDS. Initial testing of this system indicates that model-based simulators are a viable tool for testing rule-based expert systems used in health-care.
authors.affiliation: Department of Bioengineering, University of Utah, Salt Lake City.
authors.forename: R M
authors.initials: RM
authors.lastname: Sailors
authors.forename: T D
authors.initials: TD
authors.lastname: East
mesh_terms: D003198:Computer Simulation; D003661:Decision Support Techniques; D005103:Expert Systems; D006801:Humans; D008954:Models, Biological; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000628:therapy*; D013813:Therapy, Computer-Assisted