title: Intra-arterial thrombolytic therapy in the initial management of thrombosed popliteal artery aneurysms.
abstract: Case reports of three patients presenting with acute limb-threatening lower extremity ischemia as a result of thrombosed popliteal artery aneurysms are described. Intra-arterial urokinase was administered to each patient prior to definitive surgery. This improved the infrapopliteal runoff in each case, allowing for successful arterial reconstruction without limb loss.
authors.affiliation: Department of Surgery, University of Connecticut School of Medicine, Hartford Hospital 06115.
authors.forename: R R
authors.initials: RR
authors.lastname: Garramone
authors.forename: J J
authors.initials: JJ
authors.lastname: Gallagher
authors.forename: A D
authors.initials: AD
authors.lastname: Drezner
mesh_terms: D000368:Aged; D000783:Aneurysm / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D007511:Ischemia / Q000188:drug therapy; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000473:pathology* / Q000601:surgery; D017131:Thrombectomy; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use*; D014654:Vascular Patency
chemical_list: D014568:Urokinase-Type Plasminogen Activator