title: Alzheimer's disease. The apolipoprotein E connection.
abstract: One particular variant of the polymorphic protein apolipoprotein E appears to be a risk factor for Alzheimer's disease, possibly because it directly promotes anyloid formation.
authors.affiliation: Institute for Medical Biology and Human Genetics, Innsbruck, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Utermann
mesh_terms: D000368:Aged; D000483:Alleles; D000544:Alzheimer Disease / Q000209:etiology / Q000235:genetics* / Q000378:metabolism; D000682:Amyloid / Q000096:biosynthesis; D001057:Apolipoproteins E / Q000235:genetics* / Q000378:metabolism; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D008954:Models, Biological; D016874:Neurofibrillary Tangles / Q000378:metabolism; D012307:Risk Factors; D016875:tau Proteins / Q000378:metabolism
chemical_list: D000682:Amyloid; D001057:Apolipoproteins E; D016875:tau Proteins