[Effect of jiangzhi zhongyao pian on serum lipid and antioxidation of hyperlipemic patients].
62 cases of hyperlipemic patients were divided into 2 groups, 31 treated with Chinese herbal medicine Jiangzhi Zhongyao Pian (JZZYP) and the control group (31 cases) treated with placebo. Serum lipid, RBC-superoxide dismutase (RBC-SOD), and MDA were observed before and after 2 months treatment. Result showed that total cholesterol (TC), triglyceride (TG), atherogenic index (AI) and malondialdehyde (MDA) of test group were apparently dropped and high density lipid-cholesterol (HDL-C), RBC-SOD activity obviously elevated after treatment, the difference between two groups was significant (P < 0.05-0.001). The total effective rate of JZZYP on TC was 68.8%, that on TG was 86.7%. The results suggested that JZZYP has the effect of serum lipid regulation, antioxidase activity elevation and lipid peroxide inhibition. JZZYP had no side effect.
Liang
X C
XC
PUMC Hospital, Beijing.
D000328:Adult; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D013482:Superoxide Dismutase / Q000097:blood; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D004365:Drugs, Chinese Herbal; D000960:Hypolipidemic Agents; D014280:Triglycerides; D008315:Malondialdehyde; D002784:Cholesterol; D013482:Superoxide Dismutase