title: Aqueous flare in eyes with age-related macular degeneration.
abstract: It is unknown whether aqueous flare is increased in eyes with prominent fundus lesions other than choroidal malignant melanoma. Therefore, we studied the aqueous flare in eyes with age-related macular degeneration (ARMD) using the laser flare-cell meter. Forty-three eyes of 27 patients with ARMD (age 67.0 +/- 14.0 years, range 43-81 years), and 41 healthy eyes of 41 randomly selected age- and gender-matched control patients (age 68.9 +/- 9.8 years, range 43-89 years) were examined. The macular degeneration was diagnosed and classified using fluorescein angiograms. Flare values in eyes with ARMD were 0.28 +/- 0.18 mg/ml, being significant in comparison with the control (0.12 +/- 0.05 mg/ml). The differences among the subgroups of ARMD were not statistically significant (P > 0.5): macular drusenosis (0.21 +/- 0.05 mg/ml, n = 6), subretinal neovascularization without marked subretinal hemorrhage (0.27 +/- 0.15 mg/ml, n = 19), subretinal neovascularization with marked subretinal hemorrhage (0.29 +/- 0.24 mg/ml, n = 7), and disciform scar (0.31 +/- 0.24 mg/ml, n = 9).
authors.affiliation: Department of Ophthalmology, University Erlangen-Nürnberg, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Kubota
authors.forename: M
authors.initials: M
authors.lastname: Küchle
authors.forename: N X
authors.initials: NX
authors.lastname: Nguyen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001082:Aqueous Humor / Q000502:physiology*; D005260:Female; D006801:Humans; D007834:Lasers; D008268:Macular Degeneration / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009885:Ophthalmology / Q000295:instrumentation; D012166:Retinal Hemorrhage / Q000175:diagnosis; D015861:Retinal Neovascularization / Q000175:diagnosis