title: Tc-99m HMPAO brain SPECT findings in pediatric viral encephalitis.
abstract: Two children were diagnosed with viral encephalitis, due to Epstein-Barr virus infection in one case and to herpes simplex virus infection in the other. Tc-99m HMPAO brain SPECT was arranged to detect changes in regional cerebral blood flow (rCBF) secondary to viral encephalitis. During the acute episode, Tc-99m HMPAO brain SPECT showed that the two cases had increased rCBF. After the acute episode, follow-up brain SPECT was arranged 6 months later. The rCBF in one case was restored to normal on the second brain SPECT, and that in the other case was decreased. The child with normal rCBF in the follow-up brain SPECT had better learning ability and intelligence than the other child with decreased rCBF.
authors.affiliation: Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, Republic of China.
authors.forename: C H
authors.initials: CH
authors.lastname: Kao
authors.forename: S J
authors.initials: SJ
authors.lastname: Wang
authors.forename: S C
authors.initials: SC
authors.lastname: Mak
authors.forename: W J
authors.initials: WJ
authors.lastname: Shian
authors.forename: C S
authors.initials: CS
authors.lastname: Chi
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation / Q000502:physiology; D002648:Child; D018792:Encephalitis, Viral / Q000000981:diagnostic imaging*; D005260:Female; D006561:Herpes Simplex / Q000000981:diagnostic imaging*; D006566:Herpesviridae Infections / Q000000981:diagnostic imaging*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014412:Tumor Virus Infections / Q000000981:diagnostic imaging*
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime