[Criteria for and results of liver transplantation in patients with acute liver insufficiency].
OBJECTIVE
Evaluation of the results of emergency liver transplantation in patients with acute liver failure.


METHODS
Analysis of 25 patients with acute liver failure.


METHODS
University Hospital Rotterdam Dijkzigt.


METHODS
Twenty-five patients with acute liver failure were admitted to the Intensive Care Unit in January 1989-May 1993. Patients were selected for emergency liver transplantation according to the Clichy criteria (presence of confusion or coma and factor V activity less than 20-30%).


RESULTS
Liver transplantation was indicated in 17 patients and performed in 13. The 1-year survival rate in patients with a liver transplant was 85%. Four patients with an indication for liver transplantation, but who could not be transplanted died. All 8 patients without an indication for emergency liver transplantation survived.


CONCLUSIONS
Survival after liver transplantation for acute hepatic failure is now about 80%; the Clichy criteria appear to be helpful in selecting patients with acute hepatic failure for liver transplantation.
Metselaar
H J
HJ
Afd. Inwendige Geneeskunde, Academisch Ziekenhuis Rotterdam-Dijkzigt.
Tilanus
H W
HW
Ijzermans
J N
JN
Groenland
T N
TN
van den Berg
B
B
Schalm
S W
SW
D000293:Adolescent; D000328:Adult; D000075202:Contraindications; D005260:Female; D006801:Humans; D017114:Liver Failure, Acute / Q000145:classification* / Q000601:surgery* / Q000628:therapy; D016031:Liver Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011379:Prognosis
Criteria voor en resultaten van levertransplantatie bij patiënten met acute leverinsufficiëntie.