title: Genotoxicity assessment of Rokanol B2 and Rokamid R1.
abstract: Two surface-active compounds, Rokanol B2 and Rokamid R1, were examined with three types of screening tests: 1. standard Ames test in vitro using S. typhimurium TA97a, TA98, TA100 and TA102 strains; 2. micronucleus test in vivo; 3. sister chromatid exchange (SCE) on bone marrow cells of Balb C mice. Negative results of the testing, in terms of the effects of activity of both the technical preparations on S. typhimurium cells and bone marrow of Balb C mice, were found for both tested chemicals.
authors.affiliation: Department of Carcinogenesis, Teratogenesis and Mutagenesis, Nofer Institute of Occupational Medicine, Lodz, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Janik-Spiechowicz
authors.forename: B
authors.initials: B
authors.lastname: Barański
authors.forename: E
authors.initials: E
authors.lastname: Dziubałtowska
authors.forename: K
authors.initials: K
authors.lastname: Wyszyńska
authors.forename: B
authors.initials: B
authors.lastname: Przybojewska
authors.forename: W
authors.initials: W
authors.lastname: Chwiałkowska-Liro
authors.forename: J
authors.initials: J
authors.lastname: Przondo
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D051379:Mice; D008807:Mice, Inbred BALB C; D015162:Micronucleus Tests; D011092:Polyethylene Glycols / Q000633:toxicity*; D012854:Sister Chromatid Exchange; D018675:Toxicity Tests
chemical_list: D011092:Polyethylene Glycols