title: [The skin--an immunocompetent organ].
abstract: Not only is the skin a mechanical barrier vis-à-vis the external environment, it also forms part of the immunological defence system. This skin-related component of the immune system is made up of a multitude of cells, and structures such as the Langerhans cells, keratinocytes, T-lymphocytes, endothelial cells, tissue macrophages, dendritic cells and mast cells. The skin is also provided with a dense network of afferent lymphatic vessels. Taking allergic contact dermatitis as an example, an immune response in the skin is described.
authors.affiliation: Universitäts-Hautklinik Freiburg.
authors.forename: J C
authors.initials: JC
authors.lastname: Simon
mesh_terms: D000485:Allergens / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D017449:Dermatitis, Allergic Contact / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D015603:Keratinocytes / Q000276:immunology; D007801:Langerhans Cells / Q000276:immunology; D012867:Skin / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000485:Allergens
vernacular_title: Die Haut--ein Immunorgan.