title: Delayed diagnosis of spinal vascular malformations presenting as intermittent myelopathy.
abstract: We report our recent experience of three male patients, whose clinical diagnosis and subsequent surgery was delayed for 9.25 and 15 months respectively. Initially, they all presented with vague, either sensory or motor lower limb disturbances and intermittency of symptoms was followed by bladder dysfunction or impotence. Extensive laboratory work-up was unrevealing and the non-specific diagnosis of myelopathy further delayed the recognition of the underlying vascular lesion. Finally spinal magnetic resonance imaging (MRI), supine myelography and selective spinal arteriography indicated the presence of a tumor in the first patient and vascular malformation in the other two. Neurosurgery and histology confirmed one cavernous angioma and two arteriovenous malformations, all thoracic and dural. We believe that both the cryptic nature of these lesions and our technical limitations (spinal arteriography and MRI not readily available), accounted for the delayed diagnosis in our three patients, who nevertheless, when treated by surgery showed a satisfactory outcome in the first case, while further deterioration was prevented in the other two.
authors.affiliation: B' Department of Neurology, Aristotelian University, AHEPA Hospital, Thessaloniki, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Karacostas
authors.forename: N
authors.initials: N
authors.lastname: Artemis
authors.forename: I
authors.initials: I
authors.lastname: Milonas
authors.forename: S
authors.initials: S
authors.lastname: Giannopoulos
authors.forename: B
authors.initials: B
authors.lastname: Kendall
mesh_terms: D000328:Adult; D001165:Arteriovenous Malformations / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D006392:Hemangioma, Cavernous / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009192:Myelography; D011379:Prognosis; D012008:Recurrence; D013116:Spinal Cord / Q000098:blood supply*; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000601:surgery