title: Elevated anti-human T-cell lymphotropic virus type I antibody in serum of patients with retinal vasculitis and uveitis living in Izumo area.
abstract: Four patients with human T-lymphotropic virus type I associated myelopathy (HAM) were examined ophthalmologically, and serum titers to human T-lymphotropic virus type I (HTLV-I) in 11 patients with nonspecific retinal vasculitis or uveitis were determined. All of the patients lived in the Izumo area. All 4 patients with HAM (Cases 1 to 4) had vitreous opacities. Of the 11 patients with nonspecific retinal vasculitis or uveitis, 3 (Cases 5 to 7) had elevated titers to HTLV-I. We believe that HTLV-I infection may be involved in the causes of retinal vasculitis and uveitis in patients living not only in the endemic area but also outside the endemic area.
authors.affiliation: Department of Ophthalmology, Shimane Medical University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kawamoto
authors.forename: S
authors.initials: S
authors.lastname: Hayasaka
mesh_terms: D000328:Adult; D000368:Aged; D015828:Eye Infections, Viral / Q000276:immunology; D005260:Female; D015481:HTLV-I Antibodies / Q000097:blood*; D015490:HTLV-I Infections / Q000276:immunology*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D012171:Retinal Vessels / Q000276:immunology* / Q000821:virology; D015866:Uveitis, Posterior / Q000276:immunology* / Q000821:virology; D014657:Vasculitis / Q000276:immunology* / Q000821:virology
chemical_list: D015481:HTLV-I Antibodies