2',3'-Didehydro-2',3'-dideoxy-5-hydroxymethyluridine.
The furanose ring in C10H12N2O5 adopts the O(4')-endo envelope conformation (0E) and the glycosidic torsion angle C(2)--N(1)--C(1')--O(4'), chi, is 245.2 (3) degrees. The pseudo-rotational parameters are P = 102.7 degrees and tau m = 5.2 degrees. The CH2OH group on C(5') has the t conformation [gamma = 179.2 (2) degrees].
Pugazhenthi
U
U
Department of Chemistry, University of Saskatchewan, Saskatoon, Canada.
Delbaere
L T
LT
Kumar
S V
SV
Stuart
A L
AL
Gupta
S V
SV
D000998:Antiviral Agents / Q000737:chemistry*; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D014961:X-Ray Diffraction
D000998:Antiviral Agents; C090302:2',3'-didehydro-2',3'-dideoxy-5-hydroxymethyluridine; D003857:Deoxyuridine