Discordance between direct and PHA-stimulated chromosome preparations from neonates.
Four examples of discordance between karyotypes prepared from direct and PHA-stimulated neonatal blood samples are presented. The specimens were initially studied by direct methods to establish a neonatal karyotype rapidly. The patients are described and the significance of the findings is discussed.
Garnham
I W
IW
Department of Cytogenetics and Molecular Genetics, Women's and Children's Hospital, Adelaide, Australia.
Fernandez
H
H
Callen
D F
DF
Haan
E A
EA
Sutherland
G R
GR
D002478:Cells, Cultured / Q000187:drug effects; D002869:Chromosome Aberrations / Q000175:diagnosis / Q000235:genetics; D025063:Chromosome Disorders; D005260:Female; D005312:Fetal Blood / Q000166:cytology*; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007621:Karyotyping / Q000379:methods*; D008297:Male; D009030:Mosaicism; D010835:Phytohemagglutinins
D010835:Phytohemagglutinins