title: Iodixanol in femoral arteriography. A randomized, double-blind, phase III, parallel study with iodixanol 270 mg I/ml and iohexol 300 mg I/ml.
abstract: Two contrast media, iodixanol (Visipaque, Nycomed) 270 mg I/ml and iohexol (Omnipaque, Nycomed) 300 mg I/ml, were compared in femoral arteriography, in 147 patients. Both contrast media were diagnostically effective for use in femoral arteriography, without any significant difference. Pain was reported in connection with injection of iohexol by 36% of the patients, after injection of iodixanol none reported pain. Seventy-two percent of the patients in the iodixanol group reported a sensation of warmth in connection with contrast injection versus 90% in the iohexol group. The average intensity of the warmth was greater with iohexol than with iodixanol. Fourteen percent of patients in the iodixanol group and 1% in the iohexol group reported one or more subjective adverse events.
authors.affiliation: Department of Radiology, Huddinge Hospital, Karolinska Institute, Stockholm.
authors.forename: O
authors.initials: O
authors.lastname: Thorstensen
authors.forename: U
authors.initials: U
authors.lastname: Albrechtsson
authors.forename: B
authors.initials: B
authors.lastname: Calissendorff
authors.forename: H
authors.initials: H
authors.lastname: Lárusdóttir
authors.forename: L
authors.initials: L
authors.lastname: Norgren
authors.forename: M
authors.initials: M
authors.lastname: Tengvar
authors.forename: B
authors.initials: B
authors.lastname: Bolstad
authors.forename: P
authors.initials: P
authors.lastname: Aspelin
mesh_terms: D000368:Aged; D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging*; D003287:Contrast Media; D004311:Double-Blind Method; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D006801:Humans; D007472:Iohexol / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D014283:Triiodobenzoic Acids / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D003287:Contrast Media; D014283:Triiodobenzoic Acids; D007472:Iohexol; C044834:iodixanol