UCE1022, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from Paecilomyces.
Fujii
N
N
Yamashita
Y
Y
Ando
K
K
Agatsuma
T
T
Saitoh
Y
Y
Gomi
K
K
Nishiie
Y
Y
Nakano
H
H
D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002166:Camptothecin / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004249:DNA Damage; D004264:DNA Topoisomerases, Type I / Q000187:drug effects* / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D009279:Naphthacenes; D009284:Naphthols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010143:Paecilomyces / Q000737:chemistry / Q000378:metabolism*
D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes; D009284:Naphthols; C089612:UCE 1022; D004264:DNA Topoisomerases, Type I; D002166:Camptothecin