[Surgical treatment of lung cancer in patients with preoperative radiation therapy].
Combined treatment (radiotherapy--operation) was conducted in 378 patients with lung carcinoma in 1963-1991. Retrospective analysis of the immediate and late-term results of treatment showed that preoperative radiotherapy does not complicate the operative intervention. The incidence of postoperative complications is a little higher than among nonirradiated patients. Pyoinflammatory complications prevailed. Marked postradiation damage of the tumor occurred approximately in 1/3 of the patients and depended on the total largest dose of radiotherapy. Adenocarcinoma of the lung was most resistant to radiotherapy, squamous cell carcinoma and undifferentiated carcinoma were most sensitive. Total 5-year survival of patients with lung carcinoma was 35.8% after combined treatment and 42.9% after radical operations. Among patients with complete regression of the tumor after preoperative radiotherapy 63.2% of patients who underwent operation had a survival period of over 5 years.
Dobrovolśkiĭ
S R
SR
Grigoréva
S P
SP
Ivanov
A N
AN
Fishkova
Z P
ZP
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery*; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000453:epidemiology; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D012074:Remission Induction; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors
Khirurgiia raka legkogo u bolńykh s predoperatsionnym oblucheniem.