title: 8-Hydroxypenillic acid: NMR characteristics and facile formation from 6-aminopenicillanic acid.
abstract: High field NMR (1H and 13C) spectral characteristics in D2O of 8-hydroxypenillic acid and 6-aminopenicillanic acid (6-APA)-sodium bicarbonate mixtures are reported. The ready conversion of 6-APA to 8-hydroxypenillic acid is demonstrated.
authors.affiliation: School of Pharmacy and Pharmacology, University of Bath, UK.
authors.forename: A F
authors.initials: AF
authors.lastname: Casy
authors.forename: A
authors.initials: A
authors.lastname: Lipczynski
mesh_terms: D007093:Imidazoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010397:Penicillanic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D013844:Thiazoles / Q000737:chemistry*
chemical_list: D007093:Imidazoles; D013844:Thiazoles; C089999:8-hydroxypenillic acid; D010397:Penicillanic Acid; C004408:aminopenicillanic acid