title: [Immunotherapy in the combined treatment of chronic destructive pulmonary tuberculosis].
abstract: The paper provides the results of treatment of chronic pulmonary tuberculosis patients by using immunoactive drugs (thymalin and T-activin) and prednisolone, which has been performed by monitoring immunological parameters. The patients with fibrous and cavernous tuberculosis display a combination of antituberculous antibody hyperproduction and specific cell-mediated response inhibition. Immunological hormone therapy allows normalization of the immunological status (an increase in the count and functional activity of T-lymphocytes) and relative stabilization of the process with cessation of bacterial isolation in shorter periods than in the controls, which is favourable to the reduction in hospital treatment periods.
authors.forename: L A
authors.initials: LA
authors.lastname: Ivanova
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use*; D000907:Antibodies, Bacterial / Q000187:drug effects / Q000276:immunology; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D006801:Humans; D007958:Leukocyte Count; D009169:Mycobacterium tuberculosis / Q000276:immunology; D010455:Peptides / Q000494:pharmacology / Q000627:therapeutic use*; D011239:Prednisolone / Q000494:pharmacology / Q000627:therapeutic use*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013949:Thymus Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D013951:Thymus Hormones / Q000494:pharmacology / Q000627:therapeutic use*; D014397:Tuberculosis, Pulmonary / Q000276:immunology / Q000628:therapy*
chemical_list: D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D010455:Peptides; D013949:Thymus Extracts; D013951:Thymus Hormones; C032805:thymalin; C036191:T-activin; D011239:Prednisolone
vernacular_title: Immunokorrektsiia v kompleksnoĭ terapii khronicheskogo destruktivnogo tuberkulëza legkikh.