title: An archaeal S-layer gene homolog with repetitive subunits.
abstract: An S-layer protein gene homolog of the slgA gene of two Methanothermus species was found in the genome of another methanogenic archaeon of a different family, Methanosarcina mazei S-6. The new gene (slgB) encodes a molecule (SlpB) with the characteristics of S-layer proteins. The N-terminal half of SlpB is 44% identical to that encoded by SlgA, but the other half shows distinctive features: four 56 amino acid long tandem repeats, and Trp-Xaa-Trp clusters located six amino acids from the N-terminus of each repeat.
authors.affiliation: Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany.
authors.forename: R
authors.initials: R
authors.lastname: Yao
authors.forename: A J
authors.initials: AJ
authors.lastname: Macario
authors.forename: E
authors.initials: E
authors.lastname: Conway de Macario
mesh_terms: D000595:Amino Acid Sequence; D019843:Archaeal Proteins; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001426:Bacterial Proteins; D001483:Base Sequence; D005798:Genes, Bacterial / Q000235:genetics*; D017012:Methanobacteriales / Q000235:genetics; D017020:Methanosarcina / Q000235:genetics*; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
chemical_list: D019843:Archaeal Proteins; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; C090653:SlpB protein, Methanosarcina mazei; C070683:surface layer protein A, Bacteria