title: [Antisense oligonucleotides containing 1-(beta-D-2'-deoxy-threo-pentofuranosyl)thymine at the 3'- and 5'-end].
abstract: Oligonucleotides with 3'- and 5'-terminal 1-(beta-D-2'-deoxy-threo-pentafuranosyl)thymin residues (inversion at C3'-atom) were obtained by the automatic phosphoramidite synthesis. The modifications protect oligonucleotides from the nuclease degradation and do not affect the stability of nucleic acid duplexes.
authors.forename: N F
authors.initials: NF
authors.lastname: Krynetskaia
authors.forename: O A
authors.initials: OA
authors.lastname: Chebotar'
authors.forename: K Kh
authors.initials: KKh
authors.lastname: Ibragim
authors.forename: E A
authors.initials: EA
authors.lastname: Romanova
authors.forename: V N
authors.initials: VN
authors.lastname: Tashlitskiĭ
authors.forename: T S
authors.initials: TS
authors.lastname: Oretskaia
authors.forename: N I
authors.initials: NI
authors.lastname: Sokolova
authors.forename: Z A
authors.initials: ZA
authors.lastname: Shabarova
mesh_terms: D001483:Base Sequence; D008969:Molecular Sequence Data; D016376:Oligonucleotides, Antisense / Q000737:chemistry* / Q000378:metabolism; D013936:Thymidine / Q000031:analogs & derivatives* / Q000032:analysis
chemical_list: D016376:Oligonucleotides, Antisense; C077504:1-(2'-deoxy-beta-threopentofuranosyl)thymine; D013936:Thymidine
vernacular_title: Antisensovye oligonukleotidy, soderzhashchie po 3'- i 5'-kontsam 1-(beta-D'-dezoksi-treo-pentofuranozil)timin.