title: Subureteric Polytef injection in the management of vesico-ureteric reflux in children.
abstract: Subureteric Polytef injection is one of the alternatives now available for the management of vesico-ureteric reflux in children. The results of the treatment by one surgeon, over a 2 year period, were studied prospectively in 47 children (60 refluxing units). Following a single injection, reflux was abolished in 49 (82%) ureters and of the 11 failures, 10 ureters showed a reduction of the grade of reflux while one remained unchanged. A repeat injection was performed in nine of these ureters with success in five, persistence in two, and two children are awaiting a follow-up cystogram. The conservative success, with the addition of a second injection, was 90% (54/60). Of the four with unresolved reflux, two have low grade reflux and are free of infection, and two have had a ureteric reimplant, one of which was after a single injection, at the request of the parents. There were no instances of ureteric obstruction. These results show a viable, minimally invasive alternative to open ureteric reimplantation in the management of vesico-ureteric reflux in children.
authors.affiliation: Urology Unit, Women's and Children's Hospital, North Adelaide, Australia.
authors.forename: P A
authors.initials: PA
authors.lastname: Dewan
authors.forename: D W
authors.initials: DW
authors.lastname: Goh
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003558:Cystoscopy; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional / Q000009:adverse effects / Q000379:methods; D011138:Polytetrafluoroethylene / Q000008:administration & dosage / Q000627:therapeutic use*; D011446:Prospective Studies; D016896:Treatment Outcome; D014718:Vesico-Ureteral Reflux / Q000503:physiopathology / Q000628:therapy*
chemical_list: D011138:Polytetrafluoroethylene