In vivo cytogenetic studies on mice exposed to natural food colourings.
Safflower Yellow and Kokum Red, two food colourings developed from natural plant products, were assessed in vivo for their clastogenic potential. Swiss albino male mice were exposed to the compounds through ip injections. Bone marrow cells isolated from femora were analysed for chromosome aberrations. The results show that the two food colourings were weakly clastogenic.
Agarwal
K
K
Department of Botany, University of Calcutta, India.
Mukherjee
A
A
Chakrabarti
J
J
D000818:Animals; D002599:Chalcone / Q000031:analogs & derivatives* / Q000633:toxicity; D002869:Chromosome Aberrations; D005505:Food Coloring Agents / Q000633:toxicity*; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D010936:Plant Extracts
D005505:Food Coloring Agents; C089523:Kokum Red; D009153:Mutagens; D010936:Plant Extracts; C076422:safflower yellow; D002599:Chalcone