[Microangiopathic hemolytic anemia associated with neoplasms: an analysis of 5 cases and a review of the literature].
From January of 1990 to June of 1993 a diagnosis of microangiopathic hemolytic anemia (MHA) was made in 5 out off 121 new patients with malignant tumor. There were 3 females and 2 males, with a mean age of 57 yr (range: 43-75), and a primary tumor in stomach (n = 2), pancreas (n = 1) and of unknown origin (n = 2). In all cases histologic type was adenocarcinoma and diagnosis was obtained by marrow examination. Four patients developed a disseminated intravascular coagulation syndrome. Intravascular deposits of fibrin, intimal proliferation and tumoral microembolisms were noted in 2 cases. Patients did not received chemotherapy, and the median survival was 7 days (range: 3-61).
Susano
R
R
Servicio de Medicina Interna, Hospital Central de Asturias (Centro Universitario), Oviedo.
Caminal
L
L
Ferro
J
J
Rubiales
A
A
de Lera
J
J
de Quirós
J F
JF
D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000473:pathology; D000328:Adult; D000368:Aged; D000743:Anemia, Hemolytic / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009382:Neoplasms, Unknown Primary / Q000150:complications* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology
Anemia hemolítica microangiopática asociada a neoplasias: análisis de cinco casos y revisión de la literatura.