[Neutral endopeptidase (NEP)--modulator of neurogenic inflammation].
Stimulation of the sensory nerves causes the release of neuropeptides such as substance P, CGRP, neurokinin A and B. NEP cleaves and inactivates a proportion of the peptide thus limiting the neurogenic inflammation. The role of NEP have been discussed.
Gawlik
R
R
Katedra i Klinika Chorób Wewnetrznych i Alergologii Slaskiej Akademii Medycznej, Katowicach.
Karawajczyk
M
M
D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D015260:Neprilysin / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology; D015320:Tachykinins / Q000378:metabolism
D015320:Tachykinins; D015260:Neprilysin; D015740:Calcitonin Gene-Related Peptide
Obojetna endopeptydaza (NEP)--modulator zapalenia neurogennego.