Interpretation of a simple PCR analysis of the CYP2D6(A) and CYP2D6(B) null alleles associated with the debrisoquine/sparteine genetic polymorphism.
Douglas
A M
AM
Department of Forensic Medicine, Monash University, South Melbourne, Australia.
Atchison
B A
BA
Somogyi
A A
AA
Drummer
O H
OH
D000483:Alleles; D001483:Base Sequence; D019389:Cytochrome P-450 CYP2D6; D003577:Cytochrome P-450 Enzyme System / Q000172:deficiency / Q000235:genetics* / Q000378:metabolism; D017931:DNA Primers / Q000235:genetics; D003647:Debrisoquin / Q000378:metabolism; D003915:Dextromethorphan / Q000378:metabolism; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D006899:Mixed Function Oxygenases / Q000172:deficiency / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D010641:Phenotype; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017384:Sequence Deletion; D013034:Sparteine / Q000378:metabolism
D017931:DNA Primers; D013034:Sparteine; D003915:Dextromethorphan; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D019389:Cytochrome P-450 CYP2D6; D003647:Debrisoquin