Human prostatic acid phosphatase: selected properties and practical applications.
Human prostatic acid phosphatase (EC 3.1.3.2) is a non-specific phosphomonoesterase, synthetized and secreted into seminal plasma under androgenic control. The enzyme is a dimer of molecular weight around 100 kDa. Gene coding this protein is localized on chromosome 3. Since many years prostatic phosphatase has been used as a marker of diagnosis and therapy control of cancer of the prostate gland. The biological role of this enzyme, however, remains unknown and needs further exploration.
Ostrowski
W S
WS
Institute of Medical Biochemistry, Jagiellonian University, Collegium Medicum, Kraków, Poland.
Kuciel
R
R
D000135:Acid Phosphatase / Q000032:analysis / Q000502:physiology*; D000230:Adenocarcinoma / Q000175:diagnosis; D014408:Biomarkers, Tumor / Q000032:analysis; D004796:Clinical Enzyme Tests; D006801:Humans; D008297:Male; D011467:Prostate / Q000201:enzymology*; D011471:Prostatic Neoplasms / Q000175:diagnosis
D014408:Biomarkers, Tumor; D000135:Acid Phosphatase