title: First trimester diagnosis of fetal nuchal edema. Report of 29 cases.
abstract: During a 4-year period, 29 fetal nuchal edemas were observed, associated with other ultrasound abnormalities in 7 cases (24%). Fetal karyotypes were abnormal in 10 cases: 6 trisomy 21; 3 trisomy 18, and 1 Turner's syndrome. Isolated fetal nuchal edema was associated with aneuploidy in 4 cases: 3 trisomy 21, and 1 trisomy 18. The average age of the women carrying a fetus with nuchal edema associated or not with a trisomy 21 was 38.3 and 30.8 years, respectively. These results are similar to those found in the literature. It would appear that maternal age is a better marker in trisomy 21 screening than isolated fetal nuchal edema.
authors.affiliation: Center for Prenatal Diagnosis, Maternité Pellegrin, Bordeaux, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Brun
authors.forename: R
authors.initials: R
authors.lastname: Saura
authors.forename: J
authors.initials: J
authors.lastname: Horovitz
authors.forename: B
authors.initials: B
authors.lastname: Maugey
authors.forename: L
authors.initials: L
authors.lastname: Taine
authors.forename: D
authors.initials: D
authors.lastname: Roux
authors.forename: A
authors.initials: A
authors.lastname: Vergnaud
mesh_terms: D000293:Adolescent; D000328:Adult; D000782:Aneuploidy; D002869:Chromosome Aberrations; D004487:Edema / Q000000981:diagnostic imaging* / Q000235:genetics; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D009333:Neck; D011247:Pregnancy; D014314:Trisomy; D014424:Turner Syndrome; D016216:Ultrasonography, Prenatal