Magnetic resonance imaging in a patient with I-cell disease.
Autopsy reports in I-cell disease patients describe no salient abnormality of central nervous system morphology. Magnetic resonance imaging of the cranium in a patient with I-cell disease showed ventriculomegaly with frontal lobe atrophy and bifrontal leukomalacia. Central nervous system morphological abnormalities may occur in a subset of patients with I-cell disease.
Breningstall
G N
GN
Department of Pediatrics Neurology, Park Nicollet Medical Center, Minneapolis, MN 55404.
Tubman
D E
DE
D001928:Brain Diseases, Metabolic / Q000175:diagnosis* / Q000235:genetics; D002540:Cerebral Cortex / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D006867:Hydrolases / Q000097:blood; D007223:Infant; D008247:Lysosomes / Q000201:enzymology; D008279:Magnetic Resonance Imaging; D008297:Male; D008586:Meningitis, Pneumococcal / Q000175:diagnosis*; D009081:Mucolipidoses / Q000175:diagnosis* / Q000235:genetics; D009460:Neurologic Examination
D006867:Hydrolases