Gene therapy for cancer.
Recent advances in our understanding of the molecular basis of neoplasia and of the mechanics underlying activation of the immune system provide us with exciting new possibilities for the treatment of cancer. This article reviews several of the recent developments that may enter widespread clinical use by the start of the next century. Indeed, the twenty-first century may well become for medicine, the era of gene therapy and molecular pharmacology.
Kipps
T J
TJ
Department of Medicine, University of California, San Diego, La Jolla 92093-0663.
D001711:Biotransformation / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D016147:Genes, Tumor Suppressor; D015316:Genetic Therapy / Q000379:methods; D005822:Genetic Vectors; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D009369:Neoplasms / Q000235:genetics / Q000628:therapy*; D016376:Oligonucleotides, Antisense / Q000627:therapeutic use; D009857:Oncogenes
D016376:Oligonucleotides, Antisense