Mucoepidermoid carcinoma of the conjunctiva.
Mucoepidermoid carcinoma of the conjunctiva (MECa) is a rare neoplasm. It resembles squamous cell carcinoma (SCCa), clinically and histologically. Nevertheless, it is characterized by a high degree of local aggressiveness. We reviewed all cases of MECa reported in the English literature for epidemiological data, characteristics of the tumor, treatment, and outcome. We found that MECa, reported predominantly in aging males (median age 71 years), arises in the limbal and perilimbal areas. Simple excision is followed by rapid recurrence, and most tumors will require enucleation or exenteration for local control. Histological stains directed to the production of mucin are essential for the diagnosis. The recommended treatment is wide local excision. Enucleation or exenteration is recommended for tumors invading the globe or orbit.
Carrau
R L
RL
Department of Otolaryngology-Head & Neck Surgery, University of Pittsburgh, Pennsylvania.
Stillman
E
E
Canaan
R E
RE
D018277:Carcinoma, Mucoepidermoid / Q000175:diagnosis*; D003228:Conjunctiva / Q000473:pathology; D003230:Conjunctival Neoplasms / Q000175:diagnosis*; D003452:Cryosurgery; D015353:Eye Enucleation; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009915:Orbit / Q000473:pathology
D005682:Gadolinium