Neuropeptide Y and cardiovascular regulation.
Neuropeptide Y is a vasoactive peptide and is widely distributed throughout the central and peripheral nervous systems. Neuropeptide Y is co-released with noradrenaline by perivascular nerve endings. At high concentrations, it has a direct vasoconstrictor effect. In addition, it enhances the vascular effect of various agonists, including noradrenaline and angiotensin II. Moreover, neuropeptide Y has an inhibitory effect on renin secretion. This peptide may have an important role in cardiovascular regulation.
Pedrazzini
T
T
Division of Hypertension, Lausanne University Medical School, CHUV, Switzerland.
Brunner
H R
HR
Waeber
B
B
D000818:Animals; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D009478:Neuropeptide Y / Q000378:metabolism / Q000502:physiology*; D017476:Receptors, Neuropeptide Y / Q000502:physiology
D009478:Neuropeptide Y; D017476:Receptors, Neuropeptide Y