[The transport of colloidal gold-labelled albumin after its intra-abdominal administration in peritonitis].
We studied transportation of the colloidal gold labelled albumin 0.5-24 hours after intraabdominal administration of the tracer in normal rabbits and rabbits with experimental diffuse peritonitis (total 24 rabbits). Evacuation of foreign protein goes through the mesothelial stomata to the lymphatic vessels of diaphragm and further to the mediastinal lymph nodes. Sufficient amount of the tracer was captured by the phagocytes inside the lymph collectors. In case of peritonitis reticular cells of the lymph node displayed decreased capture of the tracer. This fact can be attributed to obstacles in the evacuation of the tracer from peritoneum and decreased phagocytic capacity of the reticular cells.
Manokhin
P A
PA
Glazyrin
A L
AL
Kolesnikov
S I
SI
Solodun
Iu V
IuV
Borodin
Iu I
IuI
D000005:Abdomen; D000418:Albumins / Q000008:administration & dosage / Q000493:pharmacokinetics*; D000818:Animals; D001692:Biological Transport; D004195:Disease Models, Animal; D017979:Gold Colloid; D007267:Injections / Q000379:methods; D010538:Peritonitis / Q000378:metabolism*; D011817:Rabbits; D013997:Time Factors; D014018:Tissue Distribution
D000418:Albumins; D017979:Gold Colloid
Transport mechennogo kolloidnym zolotom al'bumina posle intraabdominal'nogo vvedeniia pri peritonite.