Evaluation of three oil-adjuvant vaccines against Pasteurella multocida in buffalo calves.
Three oil-adjuvant vaccines of Pasteurella multocida 6:B were evaluated with respect to the level and duration of the humoral immune response produced in buffalo calves. Preparation 1 was a water-in-oil emulsion containing Marcol 52, Montanide 888 and antigen at a ratio of 6:1:3. Preparation 2 was a double emulsion containing Marcol 52, Arlacel A and Tween 80 in addition to antigen. Preparation 3 contained alpha-d-tocopheryl acetate (vitamin E), Montanide 888 and antigen. All three preparations induced a similar sustained immune response in buffalo calves beyond 270 days post-vaccination.
Muneer
R
R
Animal Sciences Institute, National Agricultural Research Centre, Islamabad, Pakistan.
Akhtar
S
S
Afzal
M
M
D000276:Adjuvants, Immunologic; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D001428:Bacterial Vaccines / Q000276:immunology; D002020:Buffaloes; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005069:Evaluation Studies as Topic; D007117:Immunization, Secondary / Q000662:veterinary; D010326:Pasteurella Infections / Q000517:prevention & control*; D016979:Pasteurella multocida / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary; D014810:Vitamin E / Q000276:immunology
D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D014810:Vitamin E