title: Hypothalamic-pituitary deficiency after Weil's syndrome: a case report.
abstract: A case of male hypogonadism after Weil's syndrome is described. Hypogonadism was the result of complete hypothalamic-pituitary deficiency. The relationship between leptospirosis and the endocrinopathy, the incidence that leptospira attacks hypothalamic-pituitary axis, and the mechanism with which the microorganism may cause damage to the pituitary and/or the hypothalamus are discussed.
authors.affiliation: Third Department of Obstetrics and Gynecology, Aristotelian University of Thessaloniki, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Panidis
authors.forename: D
authors.initials: D
authors.lastname: Rousso
authors.forename: S
authors.initials: S
authors.lastname: Skiadopoulos
authors.forename: D
authors.initials: D
authors.lastname: Vavilis
authors.forename: A
authors.initials: A
authors.lastname: Kalogeropoulos
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin; D002996:Clomiphene; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000627:therapeutic use; D007006:Hypogonadism / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D007027:Hypothalamic Diseases / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D007328:Insulin; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010900:Pituitary Diseases / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood / Q000627:therapeutic use; D013973:Thyrotropin-Releasing Hormone; D013974:Thyroxine / Q000627:therapeutic use; D014895:Weil Disease / Q000150:complications*
chemical_list: D006063:Chorionic Gonadotropin; D007328:Insulin; D002996:Clomiphene; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013006:Growth Hormone; D013974:Thyroxine; D006854:Hydrocortisone