title: [Otorhinolaryngologic symptoms caused by the intranasal abuse of cocaine. Report of a case].
abstract: Cocaine abuse is associated with medical complications that depends on the route of administration. Intranasal "snorting" is associated with complications secondary to chronic irritation on the nasal mucosa. A case of long-standing intranasal cocaine abuse is presented with unusual complications: septal and palatal necrosis, osteolytic sinusitis and bilateral optic neuropathy. The CT scan demonstrated a soft-tissue mass in etmoid and sphenoidal sinus and orbits. The histopathologic examination revealed a nonspecific pattern of chronic inflammation with no evidence suggestive of infection, neoplasm or lethal midline granuloma. The case had a fatal outcome. Because of the constellation of singular manifestations we discuss the differential diagnosis. Interdisciplinary approach is stressed. Emphasis is made in early diagnosis.
authors.affiliation: Servicio de Otorrinolaringología en el Hospital Santo Tomás.
authors.forename: O
authors.initials: O
authors.lastname: Sousa
authors.forename: S
authors.initials: S
authors.lastname: Rowley
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D003042:Cocaine; D005260:Female; D006801:Humans; D010038:Otorhinolaryngologic Diseases / Q000139:chemically induced*; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D003042:Cocaine
vernacular_title: Manifestaciones otorrinolaringológicas por el abuso intranasal de cocaína. A propósito de un caso.