On the general theory of neural circuitry.
A general theory of neural circuitry is proposed wherein neural impulses travel in a continuous circuit from the brain to the extremities and back to the brain. At the extremities the impulse may be modified by the environment there. At the spinal column the return signal is compared with the outgoing signal and the appropriate motoneuronal 'reflex' signal is generated if the difference is sufficiently large. In the thalamus the return signal is again compared with the outgoing signal and the difference between the two generates a sensory impulse which is sent to the cortical regions of the brain for comparison with stored patterns from similar signals of past experience. This theory allows for an explanation of feelings of pain and pleasure, pain remote from an area of trauma, phantom limb pain and the relationship between sensory impulses and motor impulses. New approaches to reducing pain are suggested by this theory.
Kingham
D J
DJ
D000818:Animals; D001921:Brain / Q000502:physiology; D006801:Humans; D008959:Models, Neurological; D009068:Movement / Q000502:physiology; D009415:Nerve Net / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D010146:Pain / Q000503:physiopathology; D059408:Pain Management; D010591:Phantom Limb / Q000503:physiopathology / Q000628:therapy; D012018:Reflex / Q000502:physiology