[Physiology of cutaneous cicatrization].
Cutaneous wound healing involves a well-coordinated cascade of cellular and molecular events in which biological processes such as proliferation, differentiation and cell migration play a key-role. Many different cell types including epithelial and mesenchymal cells are concerned. Cutaneous wound repair can be described as a three stages process: an initial inflammatory stage followed by a proliferative and repair phase ending by a remodeling stage, that overlap in time. A large number of diffusible factors (cytokines, growth factors ...) regulating these different stages have been characterized. Their therapeutic use is presently under investigation.
Ortonne
J P
JP
Service de dermatologie, hôpital Pasteur, Nice.
Clévy
J P
JP
D002455:Cell Division; D002921:Cicatrix / Q000503:physiopathology; D004817:Epidermis / Q000503:physiopathology; D006801:Humans; D012867:Skin / Q000098:blood supply / Q000293:injuries* / Q000503:physiopathology; D014945:Wound Healing / Q000502:physiology*
Physiologie de la cicatrisation cutanée.