Activated form of vitamin D [1,25(OH)2D3] and its analogs are dose-reducing agents for cyclosporine in vitro and in vivo.
Mathieu
C
C
Laboratory for Experimental Medicine and Endocrinology, K.U. Leuven, Belgium.
Waer
M
M
Laureys
J
J
Rutgeerts
O
O
Bouillon
R
R
D000818:Animals; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000494:pharmacology* / Q000627:therapeutic use; D002478:Cells, Cultured; D016572:Cyclosporine / Q000494:pharmacology* / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000628:therapy*; D006801:Humans; D016381:Islets of Langerhans Transplantation / Q000276:immunology*; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D016688:Mice, Inbred NOD; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014185:Transplantation, Isogeneic
D016572:Cyclosporine; D002117:Calcitriol