title: Production of a hemolytic factor by Candida albicans.
abstract: Candida albicans exhibits hemolytic activity when grown on glucose-enriched blood agar. This activity is present on intact organisms, and it is secreted into the culture medium. Hemoglobin released from lysed erythrocytes can restore the transferrin-inhibited growth of C. albicans. We conclude that C. albicans expresses a hemolytic factor which allows it to acquire iron from host erythrocytes.
authors.affiliation: Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
authors.forename: J M
authors.initials: JM
authors.lastname: Manns
authors.forename: D M
authors.initials: DM
authors.lastname: Mosser
authors.forename: H R
authors.initials: HR
authors.lastname: Buckley
mesh_terms: D000818:Animals; D002176:Candida albicans / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism; D006460:Hemolysin Proteins / Q000378:metabolism*; D066298:In Vitro Techniques; D007501:Iron / Q000378:metabolism; D012756:Sheep
chemical_list: D006454:Hemoglobins; D006460:Hemolysin Proteins; D007501:Iron