Genetic factors in hypertension.
Genetic approaches to hypertension have the potential to identify many of the primary abnormalities that underlie this disorder. Approaches in experimental animals and humans have advanced to the point that this is no longer merely a possibility but is a tangible reality. Successes in the past year include the mapping of a number of relevant loci and the identification of several mutations that contribute to the pathogenesis of hypertension in animals and humans.
Lifton
R P
RP
Eccles Institute of Human Genetics, University of Utah, Salt Lake City.
D000818:Animals; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology