title: Systemic amyloidosis and ovarian carcinoma.
abstract: A case of ovarian carcinoma and systemic amyloidosis in a 64 year old woman with nephrotic syndrome is reported. Immunohistochemical study of renal and rectal biopsy specimens revealed the presence of amyloidosis AA antigens, consistent with secondary amyloidosis. The absence of chronic inflammatory or infectious disease suggested the presence of a neoplasm. The gynaecological sonogram showed a solid mass located behind the uterus. Laparotomy confirmed a poorly differentiated ovarian carcinoma. The association of systemic amyloidosis and ovarian carcinoma has not to our knowledge been described previously.
authors.affiliation: Department of Medicine and Pathology, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Fernandez-Miranda
authors.forename: S
authors.initials: S
authors.lastname: Mateo
authors.forename: C
authors.initials: C
authors.lastname: Gonzalez-Gomez
authors.forename: C
authors.initials: C
authors.lastname: Ballestin
mesh_terms: D000686:Amyloidosis / Q000209:etiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology; D010051:Ovarian Neoplasms / Q000150:complications*; D012007:Rectum / Q000737:chemistry; D000685:Serum Amyloid A Protein / Q000032:analysis
chemical_list: D000685:Serum Amyloid A Protein