[Latex allergy: is the allergen thermolabile?].
The 30,000 dalton latex allergen is considered to be both hydrosoluble and thermolabile. Its thermolability does not seem to have been proved in various reviews. Three lots were prepared from an original soaking solution by different heating techniques. The prick-tests done with the three heated lots and with the original solution prove that, despite apparent contradictory results, the allergen is truly thermolabile. Could this thermolability trait be an explication for latex allergy?
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D000328:Adult; D000485:Allergens / Q000737:chemistry*; D000799:Angioedema / Q000139:chemically induced; D002675:Child, Preschool; D003233:Conjunctivitis, Allergic / Q000139:chemically induced; D017449:Dermatitis, Allergic Contact / Q000209:etiology; D009783:Dermatitis, Occupational / Q000209:etiology; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D005932:Gloves, Surgical / Q000009:adverse effects; D006358:Hot Temperature; D006801:Humans; D007840:Latex / Q000009:adverse effects* / Q000737:chemistry; D013677:Medical Laboratory Science; D011489:Protein Denaturation; D012130:Respiratory Hypersensitivity / Q000139:chemically induced; D012408:Rubber / Q000009:adverse effects
D000485:Allergens; D007840:Latex; D012408:Rubber
L'allergie au latex: l'allergène est-il thermolabile?