Intracellular motility. Profilin puts pathogens on the actin drive.
Intracellular motility of the bacterial pathogen Listeria monocytogenes depends on actin polymerization that is coordinated by the bacterial surface protein ActA and host actin-binding protein profilin.
Kocks
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Institute for Genetics, University of Cologne, Germany.
D000199:Actins / Q000378:metabolism*; D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism; D002465:Cell Movement; D003285:Contractile Proteins; D066298:In Vitro Techniques; D008089:Listeria monocytogenes / Q000378:metabolism / Q000472:pathogenicity / Q000648:ultrastructure; D008565:Membrane Proteins / Q000378:metabolism; D008840:Microfilament Proteins / Q000378:metabolism*; D008954:Models, Biological; D011108:Polymers / Q000378:metabolism; D051304:Profilins
D000199:Actins; D001426:Bacterial Proteins; D003285:Contractile Proteins; D008565:Membrane Proteins; D008840:Microfilament Proteins; D011108:Polymers; D051304:Profilins; C072980:actA protein, Listeria monocytogenes