title: Role of glutathione in cyclosporine A in vitro hepatotoxicity.
authors.affiliation: Sandoz Pharma Ltd., Drug Safety Department, Basle, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Wolf
authors.forename: C F
authors.initials: CF
authors.lastname: Trendelenburg
authors.forename: C
authors.initials: C
authors.lastname: Diez-Fernandez
authors.forename: P
authors.initials: P
authors.lastname: Prieto
authors.forename: A
authors.initials: A
authors.lastname: Cordier
mesh_terms: D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology; D019328:Buthionine Sulfoximine; D002478:Cells, Cultured; D016572:Cyclosporine / Q000633:toxicity*; D004229:Dithiothreitol / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005978:Glutathione / Q000378:metabolism*; D007700:Kinetics; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D008717:Methionine Sulfoximine / Q000031:analogs & derivatives / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis
chemical_list: D000963:Antimetabolites; D017392:Thiobarbituric Acid Reactive Substances; D008717:Methionine Sulfoximine; D019328:Buthionine Sulfoximine; D016572:Cyclosporine; D007770:L-Lactate Dehydrogenase; D005978:Glutathione; D004229:Dithiothreitol