title: High-resolution 1H NMR spectroscopy of aqueous humour from rabbits.
abstract: BACKGROUND
  Detection of different substances in aqueous humour is important for evaluation of the disorders affecting the eye. The purpose of the present study was to apply high-resolution proton (1H) nuclear magnetic resonance (NMR) spectroscopy for extensive characterisation of the metabolites in the aqueous humour from rabbits.
  
  
  METHODS
  High-resolution 1H NMR spectroscopy, including two-dimensional shift correlated (COSY) technique, was performed on aqueous humour from rabbits.
  
  
  RESULTS
  More than 20 metabolites were simultaneously detected and identified in high-resolution 1H NMR spectra of aqueous humour from rabbits. Some of these were also quantified.
  
  
  CONCLUSIONS
  High-resolution 1H NMR spectroscopy is a valuable method for simultaneous detection of many different metabolites in aqueous humour.
authors.affiliation: MR Center, SINTEF UNIMED, Trondheim, Norway.
authors.forename: I S
authors.initials: IS
authors.lastname: Gribbestad
authors.forename: A
authors.initials: A
authors.lastname: Midelfart
mesh_terms: D000818:Animals; D001082:Aqueous Humor / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D011817:Rabbits