title: [Bronchiolitis obliterans organizing pneumonia with acute respiratory insufficiency].
abstract: A 22-year-old woman was hospitalized because of fever of 39 degrees C and increasing dyspnoea. The chest radiograph demonstrated coarse confluent opacities bilaterally. Despite antibiotic treatment the condition deteriorated acutely after 2 days. All efforts to find an infectious agent, including immunological tests, were unsuccessful. Artificial ventilation became necessary because of increasing respiratory failure with an arterial oxygen partial pressure of 56 mm Hg, CO2 of 41 mm Hg and a respiratory rate of 60/min. Histological examination of a transthoracic lung biopsy revealed bronchiolitis obliterans organizing pneumonia, which was treated with prednisolone. The initial dose was 500 mg/d, gradually reduced to 12.5 mg/d over 2 weeks. The clinical and radiological findings improved markedly after 2 days and the patient discharged herself after 3 weeks and there was no follow-up.
authors.affiliation: Klinik für Innere Medizin I, Universität Wien.
authors.forename: T
authors.initials: T
authors.lastname: Staudinger
authors.forename: C
authors.initials: C
authors.lastname: Rintelen
authors.forename: M
authors.initials: M
authors.lastname: Röggla
authors.forename: M
authors.initials: M
authors.lastname: Baldt
authors.forename: F
authors.initials: F
authors.lastname: Eckersberger
authors.forename: P
authors.initials: P
authors.lastname: Tesinsky
authors.forename: C
authors.initials: C
authors.lastname: Leitner
authors.forename: M
authors.initials: M
authors.lastname: Susani
authors.forename: K
authors.initials: K
authors.lastname: Lechner
authors.forename: M
authors.initials: M
authors.lastname: Frass
mesh_terms: D000208:Acute Disease; D000328:Adult; D001706:Biopsy; D003131:Combined Modality Therapy; D018549:Cryptogenic Organizing Pneumonia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D012131:Respiratory Insufficiency / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013406:Suicide, Attempted
vernacular_title: "Bronchiolitis obliterans organizing pneumonia" mit akuter respiratorischer Insuffizienz.