T-cell selection. Accentuating the positive.
T cells can be selected positively or negatively by the same peptide under different conditions. The type of selection depends on the avidity of the interaction between the T cell and the antigen-presenting cell.
Parham
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Department of Cell Biology, Stanford University, California 94305.
D000595:Amino Acid Sequence; D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology; D006801:Humans; D008285:Major Histocompatibility Complex; D051379:Mice; D008969:Molecular Sequence Data; D010455:Peptides / Q000235:genetics / Q000276:immunology; D011110:Polymorphism, Genetic; D011948:Receptors, Antigen, T-Cell / Q000378:metabolism; D016176:T-Lymphocyte Subsets / Q000276:immunology*
D010455:Peptides; D011948:Receptors, Antigen, T-Cell