Environment-immune interactions.
The need for effective immune function for the maintenance of health has been clearly established in both agriculturally significant animal species and humans. Intensive agricultural practices present production species with numerous disease challenges during the rearing period. Environmental factors represent a ubiquitous, yet frequently manageable, category of immunomodulators that can influence immune performance and ultimately disease susceptibility or resistance. However, strategies for assessing overall immune potential have not been widely implemented for agricultural species. This is in contrast to the use of immune evaluation for human health considerations. Immune assessment relative to environmental-immune interactions can produce benefits in two areas. First, the efficiency of the production operation can be enhanced. Second, the welfare of the animals during the production cycle can be optimized. This paper presents an overview of environmental factors known to influence the immune function of poultry and the opportunities to manage environmental factors to benefit the health of the animals. In addition, the paper discusses the status of immunological assessment for humans and laboratory animals and proposes potential immune assessment panels that could serve as a tool to optimize the environmental management of poultry populations.
Dietert
R R
RR
Institute for Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853.
Golemboski
K A
KA
Austic
R E
RE
D000822:Animal Husbandry / Q000331:legislation & jurisprudence; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D004032:Diet; D004777:Environment; D006801:Humans; D007108:Immune Tolerance; D007239:Infections / Q000276:immunology / Q000662:veterinary; D008962:Models, Theoretical; D011200:Poultry / Q000276:immunology*; D011201:Poultry Diseases / Q000276:immunology; D013312:Stress, Physiological / Q000276:immunology; D013696:Temperature; D014481:United States