Malignant tumors in two patients with Diamond-Blackfan anemia treated with corticosteroids and androgens.
Two patients with Diamond-Blackfan anemia developed solid malignant tumors as young adults, carcinoma of the liver in one and carcinoma of the stomach in the other. Both had received long-term treatment with corticosteroids and androgens.
Seip
M
M
Department of Pediatrics, National Hospital, Oslo, Norway.
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D000728:Androgens / Q000009:adverse effects*; D005199:Fanconi Anemia / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology*; D008297:Male; D013274:Stomach Neoplasms / Q000209:etiology*
D000305:Adrenal Cortex Hormones; D000728:Androgens