title: Comparative analysis of the gene encoding the nucleocapsid protein of dolphin morbillivirus reveals its distant evolutionary relationship to measles virus and ruminant morbilliviruses.
abstract: A morbillivirus of uncertain origin recently killed hundreds of Mediterranean dolphins. This is the first report of the nucleotide and deduced amino acid sequence of a dolphin morbillivirus (DMV) gene. The sequence of the nucleocapsid (N) gene including boundaries was determined. When the DMV N gene coding region was compared with the corresponding sequences of other morbilliviruses a distant evolutionary relationship between these viruses and DMV was apparent. Phylogenetic analysis of the sequence data provided further evidence that DMV is not closely related to any known morbillivirus, whereas phocine distemper virus exhibits a relatively close relationship to canine distemper virus.
authors.affiliation: Laboratory of Virology and Immunology, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Blixenkrone-Møller
authors.forename: G
authors.initials: G
authors.lastname: Bolt
authors.forename: E
authors.initials: E
authors.lastname: Gottschalck
authors.forename: M
authors.initials: M
authors.lastname: Kenter
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002213:Capsid / Q000235:genetics*; D017931:DNA Primers; D004289:Dolphins / Q000821:virology; D005814:Genes, Viral; D016679:Genome, Viral; D008457:Measles / Q000235:genetics*; D008969:Molecular Sequence Data; D018103:Morbillivirus / Q000235:genetics*; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012418:Ruminants / Q000821:virology*; D017386:Sequence Homology, Amino Acid; D014758:Viral Core Proteins / Q000235:genetics*
chemical_list: D017931:DNA Primers; D014758:Viral Core Proteins