Yeast homologue of mammalian Ran binding protein 1.
A Saccharomyces cerevisiae gene (HTN1) that encodes a homologue of mouse Ran binding protein 1 (RanBP1, also known as HTF9A) was identified, cloned and sequenced. The two proteins are 51% identical in sequence. The HTN1 protein may interact with yeast GSP1, GSP2, and PRP20 proteins in an intracellular signalling pathway equivalent to the mammalian RanBP1-Ran/TC4-RCC1 pathway. RanBP1 homologues also exist in worms and rice.
Butler
G
G
Department of Biochemistry, University College Dublin, Belfield, Ireland.
Wolfe
K H
KH
D000595:Amino Acid Sequence; D001483:Base Sequence; D019204:GTP-Binding Proteins / Q000235:genetics*; D020690:GTPase-Activating Proteins; D005800:Genes, Fungal / Q000235:genetics*; D008969:Molecular Sequence Data; D009687:Nuclear Proteins; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins; D017386:Sequence Homology, Amino Acid; D020931:ran GTP-Binding Protein
D020690:GTPase-Activating Proteins; D009687:Nuclear Proteins; D029701:Saccharomyces cerevisiae Proteins; C090654:YRB1 protein, S cerevisiae; D019204:GTP-Binding Proteins; D020931:ran GTP-Binding Protein