title: [The osteogenic mechanism of vertebrogenic radiculopathies].
abstract: Intraosteal block was conducted in 86 patients with pronounced neurological symptoms of lumbar osteochondrosis. To clarify the role of the intraosteal receptors in pathogenesis of the above symptoms and to evaluate the efficacy of the blocks, series of experiments were made on 8 cats. The authors studied evoked potentials in the cerebral cortex and thalamus in response to irritation of the sciatic nerve under the exposure of the sciatic receptors to electrostimulation, intraosteal introduction of physiologic salt solution and trimecaine, electrostimulation following the introduction of the above substances. The pilot experience has been gained on facilitation of afferent current passage from the sciatic nerve under conditions of intraosteal receptor irritation as well as on inhibition of the above effect under anesthetic block of intraosteal receptors. Basing on the above findings, the authors explain osteogenic mechanism of radiculopathy and pathogenicity of the intraosteal blocks.
authors.forename: E L
authors.initials: EL
authors.lastname: Sokov
authors.forename: O A
authors.initials: OA
authors.lastname: Shevelev
mesh_terms: D000328:Adult; D000818:Animals; D001769:Blood; D001921:Brain / Q000502:physiology; D002415:Cats; D003907:Dexamethasone; D004558:Electric Stimulation; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D009407:Nerve Block / Q000379:methods; D009408:Nerve Compression Syndromes / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D009619:Nociceptors / Q000502:physiology; D010007:Osteochondritis / Q000150:complications* / Q000503:physiopathology; D013126:Spinal Nerve Roots; D013166:Spondylitis / Q000150:complications* / Q000503:physiopathology; D014288:Trimecaine
chemical_list: D003907:Dexamethasone; D014288:Trimecaine
vernacular_title: Osteogennyĭ mekhanizm vertebrogennykh radikulopatiĭ.