Elevated serum tryptase level in a case of intraoperative anaphylaxis caused by latex allergy.
We measured serial serum tryptase levels in a case of intraoperative anaphylaxis caused by allergy to latex. The serum tryptase level was elevated 7 hours after the hypotensive episode and returned to normal after recovery 4 months later. Both skin tests to latex and serum IgE to latex confirmed latex allergy in this patient. To our knowledge, this is the first report of an elevated serum tryptase level in intraoperative anaphylaxis caused by latex allergy. This observation confirms the role of mast cell degranulation in anaphylaxis caused by allergy to latex.
Volcheck
G W
GW
Division of Allergic Diseases, Mayo Clinic and Foundation, Rochester, Minn.
Li
J T
JT
D000707:Anaphylaxis / Q000097:blood* / Q000139:chemically induced / Q000503:physiopathology; D001794:Blood Pressure; D015550:Cell Degranulation / Q000276:immunology*; D053818:Chymases; D005260:Female; D006339:Heart Rate; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007431:Intraoperative Complications / Q000097:blood* / Q000139:chemically induced / Q000503:physiopathology; D008407:Mast Cells / Q000276:immunology*; D008875:Middle Aged; D012408:Rubber / Q000009:adverse effects*; D012697:Serine Endopeptidases / Q000097:blood*; D012882:Skin Tests; D013997:Time Factors; D053802:Tryptases
D007073:Immunoglobulin E; D012408:Rubber; D012697:Serine Endopeptidases; C083294:chymase 2; D053818:Chymases; D053802:Tryptases