Three new reduced anthracycline related compounds from pathogenic Nocardia brasiliensis.
Three new metabolites were isolated from a pathogenic bacterium, Nocardia brasiliensis IFM 0075 strain, a producer of a new anthracycline antibiotic (SO-075R1) and its mutant strain (IFM 0075-13-1). The structural studies showed that they are reduced anthracyline related compounds. Some biosynthetic routes of these metabolites were discussed.
Maeda
A
A
Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.
Nagai
H
H
Yazawa
K
K
Tanaka
Y
Y
Imai
T
T
Mikami
Y
Y
Kuramochi
T
T
Yamazaki
C
C
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic / Q000737:chemistry* / Q000302:isolation & purification; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009615:Nocardia / Q000378:metabolism*
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; C089894:antibiotic M-13-1; C089893:antibiotic M-3; C089892:antibiotic M-4