title: [Magnetic resonance imaging in denervated muscle. A preliminary study].
abstract: Ten patients with various forms of peripheral neuropathy and spinal radiculopathy were examined with MRI using a low-field permanent magnet (0.2 T) and spin echo (SE)/inversion recovery (IR) sequences, with an adequate inversion time to suppress healthy muscle signal. In acute denervation MR sensitivity was low on both sequences; in subacute denervation the damaged muscle was more intense than the healthy muscle only on IR sequences. MRI adequately depicted fatty infiltration in chronic denervation. In conclusion, MRI is a promising tool for mapping and noninvasively monitoring denervated motor units in skeletal muscles, whose role is currently complementary to that of electromyography.
authors.affiliation: Istituto di Radiologia, Università degli Studi di Roma Tor Vergata, IRCCS S. Lucia.
authors.forename: E
authors.initials: E
authors.lastname: Fanucci
authors.forename: S
authors.initials: S
authors.lastname: Masala
authors.forename: R
authors.initials: R
authors.lastname: Floris
authors.forename: A
authors.initials: A
authors.lastname: Apruzzese
authors.forename: L
authors.initials: L
authors.lastname: Gagliarducci
authors.forename: A
authors.initials: A
authors.lastname: Orlacchio
authors.forename: C
authors.initials: C
authors.lastname: Iani
authors.forename: G
authors.initials: G
authors.lastname: Simonetti
mesh_terms: D000208:Acute Disease; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D009132:Muscles / Q000294:innervation* / Q000473:pathology*; D009468:Neuromuscular Diseases / Q000175:diagnosis; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis; D013126:Spinal Nerve Roots / Q000473:pathology
vernacular_title: Imaging con risonanza magnetica nel muscolo denervato. Studio preliminare.