Activity of thymol, carvacrol, cinnamaldehyde and eugenol on oral bacteria.
The antimicrobial activity of thymol, carvacrol, cinnamaldehyde and eugenol alone or combined was tested by micromethods on eight oral bacteria. The compounds showed an inhibitory activity on seven microorganisms and a synergistic effect was observed with certain combinations. The four compounds can be used alone or combined, as eugenol and thymol, eugenol and carvacrol, thymol and carvacrol, during the treatment of oral infectious diseases.
Didry
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Laboratoire de Matière médicale, Faculté des Sciences Pharmaceutiques et Biologiques, Lille, France.
Dubreuil
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Pinkas
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D000171:Acrolein / Q000031:analogs & derivatives* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D000081007:Cymenes; D004357:Drug Synergism; D005054:Eugenol / Q000494:pharmacology*; D005421:Flavoring Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes; D009055:Mouth / Q000382:microbiology*; D013729:Terpenes / Q000494:pharmacology*; D013943:Thymol / Q000494:pharmacology*
D000081007:Cymenes; D005421:Flavoring Agents; D039821:Monoterpenes; D013729:Terpenes; D013943:Thymol; D005054:Eugenol; D000171:Acrolein; C073316:carvacrol; C012843:cinnamaldehyde