title: Ossified adamantinous type craniopharyngiomas. A series of 13 patients.
abstract: Thirteen patients admitted to hospital mainly with visual disturbances (100%), retarded growth (39%) and diabetes insipidus (23%) were all diagnosed as ossified adamantinous craniopharyngioma. Tumour size was found to be large in all patients. Localization displayed a heterogenous dissemination; 8% intra-suprasellar, 69% suprasellar-extraventricular, 15% extra-intraventricular, and 8% in the suprasellar region extending bilaterally to the frontal and temporal lobes. During the early postoperative period, four patients died with hypothalamic deterioration. Three patients underwent a second operation in view of recurrence, and one died from an infection. Thus, the postoperative survival rate was 62%. All the patients who survived continued to have visual disturbances, but only one deteriorated. Five patients exhibited diabetes insipidus during the postoperative period, among them 4 after surgical intervention and 5 patients displayed panhypothyroidism, three of them after surgery. Consequently, it is confirmed by the present review that craniopharyngiomas still offer a potential dilemma in their management. Difficulties caused by adhesion or invasion of ossified craniopharyngiomas and thus the increase in morbidity and mortality during surgical intervention and in the postoperative period are discussed.
authors.affiliation: Department of Neurosurgery, Hacettepe University, School of Medicine, Sihhiye, Ankara, Türkiye.
authors.forename: S
authors.initials: S
authors.lastname: Palaoğlu
authors.forename: A
authors.initials: A
authors.lastname: Akbay
authors.forename: G
authors.initials: G
authors.lastname: Mocan
authors.forename: B
authors.initials: B
authors.lastname: Onol
authors.forename: O E
authors.initials: OE
authors.lastname: Ozcan
authors.forename: T
authors.initials: T
authors.lastname: Ozgen
authors.forename: V
authors.initials: V
authors.lastname: Bertan
mesh_terms: D000293:Adolescent; D000328:Adult; D002114:Calcinosis / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D002648:Child; D003397:Craniopharyngioma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D008297:Male; D009460:Neurologic Examination; D009999:Ossification, Heterotopic / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D010902:Pituitary Gland / Q000473:pathology; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed