The structure of acnistin B and the immunosuppressive effects of acnistins A, B, and E.
The structure of the new withanolide:acnistin B, isolated from Dunalia solanacea, has been established by NMR experiments and the immunosuppressive effects of acnistins A, B and E on human lymphocytes have been measured.
Luis
J G
JG
Centro de Productos Naturales Orgánicos Antonio González, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
Echeverri
F
F
García
F
F
Rojas
M
M
D000733:Androstatrienes / Q000737:chemistry / Q000494:pharmacology*; D000736:Androstenes / Q000737:chemistry / Q000494:pharmacology*; D002478:Cells, Cultured; D006801:Humans; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000494:pharmacology*; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D009682:Magnetic Resonance Spectroscopy; D010944:Plants / Q000737:chemistry
D000733:Androstatrienes; D000736:Androstenes; D007166:Immunosuppressive Agents; C089696:acnistin B; C089697:acnistin E; C089050:acnistin A