title: [Clinical and experimental study of No. 90-dasheng jiangya oral liquid in treating hypertension].
abstract: 109 cases of hypertension patients were divided into two groups at random. No. 90 Dasheng Jiangya (DSJY) oral liquid was administered to the TCM group, while nifedipine to the control.
  
  
  RESULTS
  The level of hypertension was lowered in both TCM and control groups. The effective rates of which were 92.3% and 94.7% respectively. No significant difference was seen between them (P > 0.05). The TCM groups has an advantage of decreasing blood-lipid, increasing high density lipoprotein, improving microcirculation and reducing the atherogenic index as well. The difference between the two groups was significant (P < 0.05 or 0.01). Animal studies have shown that TCM groups has effect in decreasing blood pressure of the spontaneously hypertensive rat, and in rising of anoxia tolerance in mice. Both clinical and toxicological tests showed that this drug was non-toxic with no marked side-effects. Therefore this paper provides a basis for use of No. 90 Dasheng Jiangya oral liquid in preventing and treating hypertension.
authors.affiliation: OPD of Academy of Military Science, Beijing.
authors.forename: P S
authors.initials: PS
authors.lastname: Shi
mesh_terms: D000368:Aged; D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003228:Conjunctiva / Q000098:blood supply; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D000860:Hypoxia / Q000188:drug therapy; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D051379:Mice; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D051381:Rats; D011918:Rats, Inbred SHR; D017208:Rats, Wistar
chemical_list: D000959:Antihypertensive Agents; D004365:Drugs, Chinese Herbal; D008075:Lipoproteins, HDL