[Anomalous uterine bleeding in the perimenopause: fibromatosis, hyperplastic endometriopathy and GnRH analogs].
In the light of recent reports, the authors used GnRH analogues to treat 18 perimenopausal women with anomalous uterine bleeding, fibromatosis and endometrial hyperplasia. The aim of the study was to avoid the recurrence of anomalous bleeding, reduce hyperplastic endometriopathy and, having attained stable amenorrhea, avoid resorting to traditional surgical treatment. At the end of the study 9 women had reached the pre-established objective, 4 recommended regular menstruation, 2 reported an episode of metrorrhagia due to endometrial atrophy, and a further 2 suffered a recurrence of the initial problem and underwent hystero-annexiectomy. One patient interrupted the therapy due to the onset of arterial hypertension.
Vitale
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Divisione di Ostetricia e Ginecologia, U.S.L. n. 9, Presidio Ospedaliero di S. Vito al Tagliamento, Pordenone.
Linciano
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Salamanca
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Ferrari
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D004341:Drug Evaluation; D004714:Endometrial Hyperplasia / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D006801:Humans; D018231:Leiomyomatosis / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D008875:Middle Aged; D017697:Premenopause / Q000097:blood / Q000187:drug effects*; D012008:Recurrence; D013997:Time Factors; D014592:Uterine Hemorrhage / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D014594:Uterine Neoplasms / Q000097:blood / Q000150:complications / Q000188:drug therapy*
D007987:Gonadotropin-Releasing Hormone
Sanguinamento uterino anomalo in perimenopausa: fibromatosi, endometriopatia iperplastica ed analoghi del GnRH.