[Gastroelectric activity and gastric motility in experimental spleen deficiency rats].
Using electrode and highly sensitive strain sensor to record alterations of gastroelectric activity and gastric motility, during experimental Spleen Deficiency (SD) rats was conducted. As compared with control, frequency of slow wave (time/3 min) did not obviously change (11.71 +/- 0.71 and 12.50 +/- 0.55, P < 0.05), but amplitude (mV) of which reduced significantly (0.14 +/- 0.05 and 0.37 +/- 0.04, P < 0.01), while that of fast wave also decreased. In self-recovered group, the amplitude of slow wave recovered slightly (0.22 +/- 0.08 and 0.37 +/- 0.04, P > 0.005). After treatment with modified Sijunzi Tang ([symbol: see text]), the gastric activities of SD rats elevated to levels of control (P > 0.05), but gastric motility remained weak in SD group. Although the motility of self-recovered group improved to a certain degree, however, the main indices had no significant difference from SD group (P > 0.05). It suggested that there were significant changes of gastric activity in SD and Chinese herbs could improve the syndrome apparently.
Qu
R Y
RY
Capital College of Medicine, Beijing.
Wang
X Q
XQ
Yang
J
J
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D004594:Electrophysiology; D005769:Gastrointestinal Motility / Q000187:drug effects; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013158:Splenic Diseases / Q000188:drug therapy / Q000503:physiopathology*; D013270:Stomach / Q000503:physiopathology*; D016711:Yang Deficiency / Q000188:drug therapy / Q000503:physiopathology*
D004365:Drugs, Chinese Herbal