Permeation of rabbit common carotid arteries with dimethyl sulfoxide.
Proton nuclear magnetic resonance has been used to measure the kinetics of permeation of dimethyl sulfoxide in the common carotid artery of the rabbit. The process is described by the following exponential equations, where t = time in minutes: % Unexchanged at 2 degrees C = 70e-0.515t + 30e-0.104t and %Unexchanged at 22 degrees C = 70e-1.790t + 30e-0.146t. The times required for 95% equilibration were 13 min at 22 degrees C and 18 min at 2 degrees C. The corresponding times for 99% equilibration were 24 and 32 min, respectively.
Bateson
E A
EA
MRC Medical Cryobiology Group, University Department of Surgery, Cambridge, United Kingdom.
Busza
A L
AL
Pegg
D E
DE
Taylor
M J
MJ
D000818:Animals; D017536:Carotid Artery, Common; D015925:Cryopreservation / Q000379:methods*; D004121:Dimethyl Sulfoxide; D005260:Female; D066298:In Vitro Techniques; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D010539:Permeability; D011817:Rabbits; D013696:Temperature
D004121:Dimethyl Sulfoxide