title: Glycothiohexide alpha, a novel antibiotic produced by "Sebekia" sp., LL-14E605. II. Isolation and physical-chemical characterization.
abstract: Glycothiohexide alpha was recovered from the fermentation broth of a "Sebekia" sp. by mixed solvent extraction, selective precipitation and adsorption chromatography on Diaion HP-20. The amount of glycothiohexide alpha present in the crude preparation was enriched by photolysis. Purification of glycothiohexide alpha was accomplished by repetitive countercurrent chromatography.
authors.affiliation: Natural Products Research Section, American Cyanamid Company, Pearl River, New York 10965.
authors.forename: P T
authors.initials: PT
authors.lastname: Northcote
authors.forename: D
authors.initials: D
authors.lastname: Williams
authors.forename: J K
authors.initials: JK
authors.lastname: Manning
authors.forename: D B
authors.initials: DB
authors.lastname: Borders
authors.forename: W M
authors.initials: WM
authors.lastname: Maiese
authors.forename: M D
authors.initials: MD
authors.lastname: Lee
mesh_terms: D000192:Actinomycetales / Q000737:chemistry* / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002942:Circular Dichroism; D009682:Magnetic Resonance Spectroscopy; D010455:Peptides; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000900:Anti-Bacterial Agents; D010455:Peptides; C089609:glycothiohexide alpha