[Usefulness of establishing chosen acute phase proteins concentrations in serum and cerebrospinal fluid for differential diagnosis and monitoring of purulent meningitis in adults. II].
40 adult patients were examined: 24 with purulent meningitis and 16 with lymphocytic meningitis. In the course of purulent meningitis concentrations of the following acute phase proteins were measured in the cerebrospinal fluid: C-reactive protein, alpha 1-antitripsin, alpha 1-orosomucoid, alpha 2-ceruloplasmin, alpha 2-macroglobulin and alpha 2-haptoglobin in the 1st, 3rd, 5th, 7th, 14th and 28th day of the disease. In lymphocytic meningitis patients concentrations of the above mentioned acute phase proteins were measured only in the 1st day of the disease. Full usefulness of establishing concentrations of all the above mentioned acute phase proteins within the first five days of the purulent meningitis for differential diagnosis of purulent and lymphatic meningitis was proved. Evaluation of concentration kinetics of acute phase proteins in cerebrospinal fluid for monitoring of the course of purulent meningitis is of a limited value.
Lobos
M
M
Zakład Diagnostyki Laboratoryjnej, Wojskowej Akademii Medycznej im. gen dyw. Boleława Szareckiego w Lodzi.
Paradowski
M
M
Kuydowicz
J
J
Krakowiak
M
M
Kubasiewicz-Ujma
B
B
Wrodycki
W
W
D000328:Adult; D000368:Aged; D002570:Ceruloplasmin / Q000134:cerebrospinal fluid*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008259:Macroglobulins / Q000134:cerebrospinal fluid*; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid*; D008875:Middle Aged; D009961:Orosomucoid / Q000134:cerebrospinal fluid*; D011486:Protein C / Q000134:cerebrospinal fluid*; D000515:alpha 1-Antitrypsin / Q000134:cerebrospinal fluid*
D008259:Macroglobulins; D009961:Orosomucoid; D011486:Protein C; D000515:alpha 1-Antitrypsin; D002570:Ceruloplasmin
Przydatność oznaczania stezeń wybranych białek ostrej fazy w surowicy krwi i płynie mózgowo-rdzeniowym do diagnostyki róznicowej i monitorowania przebiegu ropnych zapaleń opon mózgowo-rdzeniowych u dorosłych. II. Stezenie białek ostrej fazy w płynie mózgowo-rdzeniowym.