Detection of Chlamydia trachomatis antigen & Toxoplasma gondii (IgM) & Mycoplasma hominis (IgG) antibodies by ELISA in women with bad obstetric history.
A total of 365 non pregnant women with bad obstetrics history (BOH) were studied with a control group of 100 women who had delivered full term clinically normal infants. The presence of C. trachomatis antigen and T. gondii (IgM) and M. hominis (IgG) antibodies was assessed by ELISA test. C. trachomatis antigen was detected in 28.2 per cent of women with BOH whereas T. gondii and M. hominis specific antibodies were found in 43.83 and 27.1 per cent respectively, these were highly significant (P < 0.001) in comparison with the control group. In case, facilities for culture are not available then detection of antigen and IgM class of antibodies by ELISA can pinpoint current infection.
Gogate
A
A
Department of Microbiology, LTM Medical College, Bombay.
Deodhar
L P
LP
Shah
P K
PK
Vaidya
P
P
D000026:Abortion, Habitual / Q000382:microbiology*; D000328:Adult; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000913:Antibodies, Protozoan / Q000032:analysis; D000942:Antigens, Bacterial / Q000032:analysis; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D009175:Mycoplasma Infections / Q000175:diagnosis; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D014123:Toxoplasmosis / Q000175:diagnosis*
D000907:Antibodies, Bacterial; D000913:Antibodies, Protozoan; D000942:Antigens, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M