[Correlation between serum adenosine deaminase, peripheral T lymphocyte subsets and syndrome types of traditional Chinese medicine in liver-cirrhosis patients].
Serum adenosine deaminase (ADA) of 74 liver cirrhosis patients and 100 healthy subjects as control were examined with improved Martinek microassay and peripheral T lymphocyte subsets of 38 liver cirrhosis patients and 60 healthy subjects studied by indirect immunofluorescence assay (IFA) for exploring the relationship between them and syndrome types of TCM. The result showed that level of ADA of liver cirrhosis patients was higher than that of control (P < 0.01) and increased in following order: the type of Liver-energy Depression and Spleen Deficiency, that of Heat-Stagnation and Blood Stasis and that of Yin-Deficiency and Microvessel Obstruction. The difference of serum ADA among the types were significant (P < 0.01). The result also showed that OKT8 of liver cirrhosis patients was higher, the ratio of OKT4/OKT8 was lower than the healthy subjects (P < 0.05-0.01), but the difference among the types were not significant (P > 0.05). Serum ADA seemed to be one of the reference indexes in differentiating syndrome types of TCM, determining the patient's condition and prognosis.
Deng
Y Q
YQ
Dept. of TCM, 1st Affiliated Hospital, Zhejiang Medical Univ., Hangzhou.
D000243:Adenosine Deaminase / Q000097:blood*; D000328:Adult; D000368:Aged; D016516:CD4-CD8 Ratio; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000145:classification / Q000201:enzymology* / Q000276:immunology*; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D011379:Prognosis; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D016710:Yin Deficiency / Q000201:enzymology / Q000276:immunology
D000243:Adenosine Deaminase