Synthesis and pharmacological screening of derivatives of isoxazolo[4, 3-d]pyridimidine.I.
The synthesis of new derivatives of isoxazole and new derivatives of isoxazolo[4,3-d]pyridine is described. The anticonvulsant and anxiolytic activity of some isoxazolo[4,3-d]pyrimidine derivatives was tested in a preliminary screening.
Poreba
K
K
Department of Technology of Drugs, Medical Academy, Wroclaw, Poland.
Wagner
E
E
Jakowicz
I
I
Balika
D
D
D000818:Animals; D014151:Anti-Anxiety Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology; D007555:Isoxazoles / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D008297:Male; D051379:Mice
D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D007555:Isoxazoles