Absence seizures and carbamazepine in adults.
Carbamazepine (CBZ) therapy was associated with development of absence seizures in 4 adults with generalized epilepsy. Two patients had new appearance of absence seizures and 2 patients had recrudescence of remote absence seizures. The seizures abated after discontinuation of CBZ therapy or addition of ethosuximide (ESM) in 1 patient intolerant of valproate (VPA).
Liporace
J D
JD
Department of Neurology, University of Pennsylvania, Graduate Hospital, Philadelphia.
Sperling
M R
MR
Dichter
M A
MA
D000328:Adult; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004832:Epilepsy, Absence / Q000139:chemically induced* / Q000188:drug therapy; D004829:Epilepsy, Generalized / Q000188:drug therapy*; D005013:Ethosuximide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D012008:Recurrence
D002220:Carbamazepine; D005013:Ethosuximide