title: Synthesis and pharmacological screening of derivatives of isoxazolo[4, 3-d]pyridimidine.I.
abstract: The synthesis of new derivatives of isoxazole and new derivatives of isoxazolo[4,3-d]pyridine is described. The anticonvulsant and anxiolytic activity of some isoxazolo[4,3-d]pyrimidine derivatives was tested in a preliminary screening.
authors.affiliation: Department of Technology of Drugs, Medical Academy, Wroclaw, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Poreba
authors.forename: E
authors.initials: E
authors.lastname: Wagner
authors.forename: I
authors.initials: I
authors.lastname: Jakowicz
authors.forename: D
authors.initials: D
authors.lastname: Balika
mesh_terms: D000818:Animals; D014151:Anti-Anxiety Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology; D007555:Isoxazoles / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D008297:Male; D051379:Mice
chemical_list: D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D007555:Isoxazoles