title: Severe dysphagia associated with major tranquillizer treatment.
abstract: A 56 year old patient with psychiatric complications of systemic lupus erythematosus developed severe dysphagia complicated by weight loss and aspiration. Following investigation it was concluded that the addition of haloperidol to her treatment was the major precipitating cause and withdrawal of the drug was followed by an objective improvement in swallowing. Patients taking major transquillizers may be at increased risk of severe dysphagia; regular observation of swallowing is suggested as a useful addition to the clinical examination of these patients.
authors.affiliation: Department of Neurology, University Hospital of Wales, Heath Park, Cardiff, UK.
authors.forename: T A
authors.initials: TA
authors.lastname: Hughes
authors.forename: G
authors.initials: G
authors.lastname: Shone
authors.forename: G
authors.initials: G
authors.lastname: Lindsay
authors.forename: C M
authors.initials: CM
authors.lastname: Wiles
mesh_terms: D003679:Deglutition; D003680:Deglutition Disorders / Q000139:chemically induced*; D004947:Esophagus / Q000000981:diagnostic imaging; D005260:Female; D006220:Haloperidol / Q000009:adverse effects*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008875:Middle Aged; D010614:Pharynx / Q000000981:diagnostic imaging; D011859:Radiography; D014741:Video Recording
chemical_list: D006220:Haloperidol