title: [Quinolone-resistant Escherichia coli in the health area of a 650-bed hospital].
abstract: Report of a retrospective study to evaluate susceptibility of Escherichia coli to quinolones covering the March-December 1992 interval. During this time, intra and extra-hospital strains were indistinctly studied in patients with urinary infections seen in a health district serving a total of 200.000 inhabitants. Resistance to Pipemidic acid, Norfloxacin and Ciprofloxacin was evaluated. The values found were 14.8% resistance to Pipemidic acid, 11.1% to Norfloxacin and 8.5% to Ciprofloxacin. It seems necessary to develop and apply methods addressed to minimize the appearance of quinolone resistance, which should be implemented in order to preserve the usefulness of these drugs.
authors.affiliation: Servicio de Urología, Complejo Hospitalario San Millan-San Pedro, Logroño, La Rioja.
authors.forename: A
authors.initials: A
authors.lastname: Fernández Fernández
authors.forename: M
authors.initials: M
authors.lastname: Lantero Benedito
authors.forename: M J
authors.initials: MJ
authors.lastname: Gastañares Hernando
authors.forename: E
authors.initials: E
authors.lastname: Undabeitia Santisteban
authors.forename: F
authors.initials: F
authors.lastname: Fernández Santos
authors.forename: A
authors.initials: A
authors.lastname: Castaño Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Gil Fabra
authors.forename: F
authors.initials: F
authors.lastname: Martínez Castellanos
authors.forename: G
authors.initials: G
authors.lastname: Otero Mauricio
mesh_terms: D002391:Catchment Area, Health; D002939:Ciprofloxacin / Q000494:pharmacology* / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects*; D006746:Hospital Bed Capacity, 500 and over; D006801:Humans; D008826:Microbial Sensitivity Tests; D009643:Norfloxacin / Q000494:pharmacology* / Q000627:therapeutic use; D010876:Pipemidic Acid / Q000494:pharmacology* / Q000627:therapeutic use; D012189:Retrospective Studies; D013030:Spain; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology
chemical_list: D002939:Ciprofloxacin; D010876:Pipemidic Acid; D009643:Norfloxacin
vernacular_title: Escherichia coli resistente a quinolonas en el area sanitaria de un hospital de 650 camas.