Identification of human monoamine oxidase (MAO) A and B gene promoters.
The promoter of human monoamine oxidase (MAO) A and B genes have been identified. The core promoter region of MAO A is comprised of two 90 bp repeats each of which contains two Sp1 elements and lacks a TATA box. The MAO B core promoter region contains two sets of overlapping Sp1 sites which flank a CACCC element all upstream of a TATA box. The different organization of the MAO A and B promoters may underlie their different cell and tissue specific expression.
Shih
J C
JC
Department of Molecular Pharmacology and Toxicology, School of Pharmacy, University of Southern California, Los Angeles.
Zhu
Q S
QS
Grimsby
J
J
Chen
K
K
D001483:Base Sequence; D017353:Gene Deletion; D006801:Humans; D008969:Molecular Sequence Data; D008995:Monoamine Oxidase / Q000235:genetics*; D011401:Promoter Regions, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D016385:TATA Box
D008995:Monoamine Oxidase