title: Sequelae of massive fluid resuscitation in trauma patients.
abstract: The severely injured trauma patient presents to the critical care unit with multiple physiologic derangements. The sequelae of massive volume infusion necessary to restore tissue oxygenation in hemorrhagic shock include hypothermia, coagulopathies, electrolyte abnormalities, acidosis, and organ dysfunction. Therapeutic interventions are directed toward minimizing and reversing these derangements, rapid restitution of oxygen transport, and tissue oxygen uptake.
authors.forename: K T
authors.initials: KT
authors.lastname: Von Rueden
authors.forename: C M
authors.initials: CM
authors.lastname: Dunham
mesh_terms: D002985:Clinical Protocols; D003422:Critical Care; D005440:Fluid Therapy / Q000009:adverse effects*; D006801:Humans; D009104:Multiple Trauma / Q000628:therapy*; D012151:Resuscitation / Q000009:adverse effects*