[Recently discovered frequent cause of venous thrombosis: factor V Leiden, a mutated factor V, resistant against protein C inactivation].
Rosendaal
F R
FR
Academisch Ziekenhuis, afd. Hematologie en Klinische Epidemiologie, Leiden.
D001777:Blood Coagulation; D001779:Blood Coagulation Factors / Q000502:physiology; D005165:Factor V / Q000037:antagonists & inhibitors / Q000235:genetics; D006801:Humans; D009154:Mutation; D011486:Protein C / Q000494:pharmacology*; D013924:Thrombophlebitis / Q000097:blood* / Q000503:physiopathology; D013927:Thrombosis / Q000503:physiopathology
D001779:Blood Coagulation Factors; D011486:Protein C; D005165:Factor V
Onlangs ontdekte frequente oorzaak van veneuze trombose: factor V Leiden, een gemuteerde factor V, resistent tegen inactivering door proteïne C.