An apparent unusual relationship between rampant caries and the oral mucosal manifestations of chronic graft-versus-host disease.
Oral complications of chronic graft-versus-host disease are well known and may be present in up to 80% of persons with the condition. A case involving a 29-year-old woman with chronic graft-versus-host disease after allogeneic bone marrow transplantation is presented to illustrate how oral mucosal lesions may be adversely affected by severe caries. A variety of extensive mucosal lesions were continually irritated by the sharp edges of the carious teeth. Full-mouth extractions facilitated the complete resolution of the oral lesions. The patient has had no recurrence of oral lesions 4 years after the extractions and has shown no adverse mucosal changes 3 1/2 years after rehabilitation with complete dentures.
Curtis
J W
JW
Department of Oral Rehabilitation, School of Dentistry, Medical College of Georgia.
Caughman
G B
GB
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D002180:Candidiasis, Oral / Q000150:complications; D002908:Chronic Disease; D003731:Dental Caries / Q000150:complications*; D003824:Denture, Complete; D003937:Diagnosis, Differential; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications* / Q000209:etiology; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000601:surgery; D009059:Mouth Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D009061:Mouth Mucosa / Q000293:injuries*; D014081:Tooth Extraction; D014987:Xerostomia / Q000150:complications / Q000209:etiology