title: Radionuclide detection of dialysate leakage in patients on continuous ambulatory peritoneal dialysis.
abstract: While continuous ambulatory peritoneal dialysis (CAPD) offers several advantages over haemodialysis in patients with end-stage renal disease, several complications have been recognised. The intraperitoneal instillation of dialysate increases intra-abdominal pressure and consequently predisposes to leaks and herniations through defects in the abdominal wall. This can lead to disruption of CAPD therapy. Peritoneal scintigraphy with Tc99m colloid has been used to identify such leaks of dialysate. This report analyses the clinical role of peritoneal scintigraphy in patients on the CAPD programme in the Singapore General Hospital. The results of 25 scans performed over a two-and-a-half year period were correlated with clinical and surgical findings. The clinical presentations of suspected dialysate leakage were varied, but can be broadly classified into three subsets for this analysis: (A) swellings confined to the inguinal and genital region, (B) peri-catheter, umbilical and incisional swellings, and (C) diffuse pattern of swellings in the abdominal wall, pelvic and genital region. In group A, the scan proved to be clearly helpful, correctly identifying 10/10 inguinal hernias, all of which resolved after herniorrhaphy. In group B, the scan correctly identified 7/9 leaks and hernias in the ventral abdominal wall. There was one false negative scan in a patient with a peri-catheter leak, and an equivocal result in another with fluid leakage in the lower anterior abdominal wall. In group C, which presented the greatest difficulty in clinical diagnosis, 2/3 cases were correctly diagnosed by scintigraphy. An equivocal result was seen in a patient who had had multiple operations for recurrent incisional hernias.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Nuclear Medicine, Singapore General Hospital.
authors.forename: A S
authors.initials: AS
authors.lastname: Goh
authors.forename: G S
authors.initials: GS
authors.lastname: Lee
authors.forename: S G
authors.initials: SG
authors.lastname: Kee
authors.forename: E S
authors.initials: ES
authors.lastname: Ang
authors.forename: F X
authors.initials: FX
authors.lastname: Sundram
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation; D015314:Dialysis Solutions / Q000009:adverse effects*; D004487:Edema / Q000000981:diagnostic imaging / Q000209:etiology; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006552:Hernia, Inguinal / Q000000981:diagnostic imaging / Q000209:etiology; D006554:Hernia, Umbilical / Q000000981:diagnostic imaging / Q000209:etiology; D006555:Hernia, Ventral / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects* / Q000295:instrumentation; D010537:Peritoneum / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013667:Technetium; D013997:Time Factors
chemical_list: D015314:Dialysis Solutions; D013667:Technetium