title: Reinterpretation of the genetics of susceptibility of Aedes aegypti to Plasmodium gallinaceum.
abstract: Several studies have demonstrated a genetic basis for variation in susceptibility of Aedes aegypti to Plasmodium gallinaceum. Although 25 yr ago it was reported that P. gallinaceum susceptibility in Ae. aegypti is determined primarily by a single autosomal dominant gene, evidence for additional genetic factors has emerged. Two sublines, 1 refractory and 1 of intermediate susceptibility to P. gallinaceum, have been selected from the Moyo-In-Dry strain (MOYO) of Ae. aegypti. Prior to selection, the MOYO population was 20.3% refractory. Genetic crosses of the highly susceptible Rockefeller strain (ROCK) and the 2 selected sublines of the MOYO strain provide evidence for a complex mode of inheritance of Plasmodium susceptibility in Ae. aegypti.
authors.affiliation: Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison 53706.
authors.forename: V
authors.initials: V
authors.lastname: Thathy
authors.forename: D W
authors.initials: DW
authors.lastname: Severson
authors.forename: B M
authors.initials: BM
authors.lastname: Christensen
mesh_terms: D000330:Aedes / Q000235:genetics / Q000276:immunology / Q000469:parasitology*; D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D014644:Genetic Variation; D008297:Male; D010375:Pedigree; D010964:Plasmodium gallinaceum / Q000276:immunology*; D012641:Selection, Genetic