Phototransduction. Shedding light on recoverin.
The crystal structure of recoverin reveals two functional Ca2+-binding sites and a surface hydrophobic feature that may be important for membrane-binding and recoverin's role in the rod cell's recovery from light.
Head
J F
JF
Department of Physiology, Boston University School of Medicine, Massachusetts 02118.
D000818:Animals; D000951:Antigens, Neoplasm / Q000737:chemistry; D001665:Binding Sites; D002118:Calcium / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000737:chemistry* / Q000378:metabolism / Q000528:radiation effects; D018360:Crystallography, X-Ray; D005136:Eye Proteins; D051597:Hippocalcin; D008027:Light; D008074:Lipoproteins; D008954:Models, Biological; D009419:Nerve Tissue Proteins; D010786:Photoreceptor Cells / Q000502:physiology; D017433:Protein Structure, Secondary; D051603:Recoverin; D012160:Retina / Q000502:physiology
D000951:Antigens, Neoplasm; D002135:Calcium-Binding Proteins; D005136:Eye Proteins; D008074:Lipoproteins; D009419:Nerve Tissue Proteins; D051603:Recoverin; D051597:Hippocalcin; D002118:Calcium