Severe pneumonia in pregnancy three months after resolution of cutaneous zoster.
A 22 weeks pregnant women was affected by a life-threatening pneumonia and a paresis of the proximal muscles with cerebrospinal fluid pleocytosis. Her past medical history had been unremarkable except for recurrent episodes of paraumbilical herpes zoster. The clinical findings suggested a dissemination of varicella-zoster virus without skin lesions. Acyclovir was added to the therapy, and the clinical picture began to improve. Varicella-zoster virus DNA was detected in placental tissue by DNA-hybridisation analysis.
Moling
O
O
Sektion für Infektionskrankheiten, Medizinische Abt. I, Allgemeines Regionalkrankenhaus Bozen, Italy.
Mayr
O
O
Gottardi
H
H
Mian
P
P
Zanon
P
P
Oberkofler
F
F
Gramegna
M
M
Colucci
G
G
D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006562:Herpes Zoster / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D014645:Herpesvirus 3, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D009693:Nucleic Acid Hybridization; D010920:Placenta / Q000382:microbiology*; D011024:Pneumonia, Viral / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D011262:Pregnancy Trimester, Second; D013997:Time Factors; D014472:Umbilicus
D004279:DNA, Viral; D000212:Acyclovir