[The effect of different hyperbaric oxygenation regimens on the aggregate status of the blood and on the free-radical oxidation processes in patients with the initial manifestations of cerebral blood supply failure].
Blood rheology, hemocoagulation, free-radical oxidation, acid-alkaline condition of the capillary and venous blood were investigated in 62 ICIB patients before and after treatment which consisted of 8 hyperbaric oxygenation (HBO) sessions or 3 HBO sessions (1.5 atm and 1,2 atm, respectively), the rest patients were not exposed to HBO. The best therapeutic results were achieved with a short-term HBO at a small excessive pressure. The longer HBO regimen provided no positive tendencies in clinical parameters. On the contrary, it provoked blood rheology deterioration, activation of free-radical oxidation stemming from diminished adaptation to hyperoxia in ICIB.
Kazantseva
N V
NV
Gusev
E I
EI
Solovykh
N N
NN
Voskresenskaia
O N
ON
D000293:Adolescent; D000328:Adult; D001809:Blood Viscosity; D002561:Cerebrovascular Disorders / Q000097:blood* / Q000628:therapy*; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004903:Erythrocyte Aggregation; D005260:Female; D005609:Free Radicals / Q000097:blood; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D015227:Lipid Peroxidation; D008297:Male; D008875:Middle Aged
D005609:Free Radicals
Vliianie razlichnykh rezhimov giperbaricheskoĭ oksigenatsii na agregatnoe sostoianie krovi i protsessy svobodnoradikal'nogo okisleniia u bol'nykh s nachal'nymi proiavleniiami nedostatochnosti krovosnabzheniia mozga.