title: Evaluation of Nigerian traditional medicines: 1. Plants used for rheumatic (inflammatory) disorders.
abstract: In continuation of our evaluation of the Nigerian traditional medicine system which forms an important part of health care delivery, we investigated some plants attributed to possess potent anti-rheumatic activity. Ten plant species representing 9 different families were screened for anti-inflammatory activity. The extracts were tested for anti-inflammatory activity against acute inflammation induced by two phlogistic agents. Acute toxicity testing and phytochemical analyses were carried out. The results revealed significant anti-inflammatory activity of all extracts tested against acute inflammation.
authors.affiliation: Department of Pharmacology and Toxicology, University of Nigeria, Nsukka.
authors.forename: P A
authors.initials: PA
authors.lastname: Akah
authors.forename: A I
authors.initials: AI
authors.lastname: Nwambie
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology* / Q000633:toxicity; D018501:Antirheumatic Agents / Q000494:pharmacology* / Q000633:toxicity; D004487:Edema / Q000188:drug therapy; D005069:Evaluation Studies as Topic; D005260:Female; D007249:Inflammation / Q000188:drug therapy*; D007928:Lethal Dose 50; D008297:Male; D016488:Medicine, African Traditional; D010936:Plant Extracts / Q000494:pharmacology* / Q000633:toxicity; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D012216:Rheumatic Diseases / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D010936:Plant Extracts