Probing the specificity of the S1 binding site of subtilisin Carlsberg with boronic acids.
Seufer-Wasserthal
P
P
Department of Chemistry, University of Toronto, Lash Miller Laboratories, Canada.
Martichonok
V
V
Keller
T H
TH
Chin
B
B
Martin
R
R
Jones
J B
JB
D000495:Allosteric Site; D001665:Binding Sites; D001667:Binding, Competitive; D001897:Boronic Acids / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D004563:Electrochemistry; D066298:In Vitro Techniques; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D013381:Subtilisins / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism*; D013816:Thermodynamics
D001897:Boronic Acids; D013381:Subtilisins