title: [Meningeal carcinomatosis. Review of 30 cases].
abstract: The clinical features of 30 patients with carcinomatous meningitis caused by solid tumors are reported. The most common originating sites of tumors were lung (12 cases) and breast (9 cases). Headache was the most common presenting symptom and there was involvement in more than one level of neuro-axis in 53% of cases. The CSF from the first lumbar puncture was abnormal in all cases; pleocytosis and an increased protein level in CSF were of great diagnostic value when a positive cytology was absent. Only three patients were treated with intrathecal chemotherapy, with a median survival of six weeks since the onset of symptoms.
authors.affiliation: Servicio de Neurología, Hospital General de Asturias, Oviedo.
authors.forename: V
authors.initials: V
authors.lastname: Pérez de Colosía
authors.forename: A
authors.initials: A
authors.lastname: Tuñón
authors.forename: I
authors.initials: I
authors.lastname: Peláez
authors.forename: L
authors.initials: L
authors.lastname: Caminal
authors.forename: A
authors.initials: A
authors.lastname: Astudillo
authors.forename: C H
authors.initials: CH
authors.lastname: Lahoz
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000293:Adolescent; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000556:secondary*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis; D008875:Middle Aged
vernacular_title: Carcinomatosis meníngea. Revisión de 30 casos.