title: Preliminary screening of methanolic extracts of Celastrus paniculatus and Tecomella undulata for analgesic and anti-inflammatory activities.
abstract: Flowers of Celastrus paniculatus and whole plant of Tecomella undulata were extracted individually in absolute methanol. Using the hot water tail immersion test in mice and carrageenan induced pedal edema in rats, both extracts were tested for their oral analgesic and anti-inflammatory potentials. Results showed that C. paniculatus had both analgesic and anti-inflammatory activities, while T. undulata had only analgesic potential when compared with aspirin.
authors.affiliation: Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Pakistan.
authors.forename: F
authors.initials: F
authors.lastname: Ahmad
authors.forename: R A
authors.initials: RA
authors.lastname: Khan
authors.forename: S
authors.initials: S
authors.lastname: Rasheed
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001241:Aspirin / Q000494:pharmacology; D004487:Edema / Q000188:drug therapy; D005260:Female; D008297:Male; D000432:Methanol; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D001241:Aspirin; D000432:Methanol