title: Pregnancy rates in a donor sperm program using cryopreservation: effects of total number of motile sperm inseminated and of a procedure to concentrate sperm.
abstract: OBJECTIVE
  To determine the relationship between the total number of motile sperm per insemination (TMSI) and pregnancy rates in a donor insemination program. To determine the effect of sperm concentration and resultant increase of TMSI on pregnancy rates.
  
  
  METHODS
  Retrospective analysis of pregnancy rates.
  
  
  METHODS
  University hospital with tertiary service.
  
  
  METHODS
  179 women undergoing donor insemination.
  
  
  METHODS
  None.
  
  
  METHODS
  Calculation of pregnancy rates according to TMSI.
  
  
  RESULTS
  The pregnancy rate with insemination of thawed donor sperm increases when the TMSI of unconcentrated sperm is > or = 80 x 10(6). Pregnancy rates with previously concentrated sperm are as good as or better than rates of unconcentrated specimens.
  
  
  CONCLUSIONS
  TSMI is important in determining pregnancy rates in donor insemination programs, and concentration of sperm prior to freezing may enhance pregnancy rates by increasing the TMSI.
authors.affiliation: Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington.
authors.forename: D B
authors.initials: DB
authors.lastname: Maier
authors.forename: S S
authors.initials: SS
authors.lastname: Kuslis
authors.forename: A A
authors.initials: AA
authors.lastname: Luciano
mesh_terms: D015925:Cryopreservation; D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D012661:Semen; D012662:Semen Preservation; D013076:Sperm Count; D013081:Sperm Motility