[Favorable results of nocturnal nasal positive-pressure ventilation in 64 patients with neuromuscular disorders; 5-year experience].
OBJECTIVE
Evaluation of the effectiveness of chronic nightly mechanical ventilation through a nasal mask system in patients with neuromuscular diseases or patients with thorax malformations or COPD.


METHODS
Centre for Home Mechanical Ventilation, University Hospital Utrecht.


METHODS
Retrospective study.


METHODS
During the period June 1988-May 1993, 64 patients (11-69 years old) were treated with nasal mask ventilation during the night: 37 men (most of whom had Duchenne's disease (18) and 27 women (most of whom had (post-polio) kyphoscoliosis (n = 13). The effects on arterial blood gases were analysed. Complications during use of the nasal mask systems were recorded.


RESULTS
The duration of the nasal mask ventilation was 2 to 56 months. Arterial PCO2 and PO2 improved during the night as well as by day during spontaneous respiration. The most common problems were necrosis of the skin of the bridge of the nose, leakage of air through the mouth or insufflation of air into the stomach. After the start of the mechanical ventilation quality of life improved considerably.


CONCLUSIONS
Nasal ventilation at night is sufficient and simple. The installation of a tracheostoma can be postponed or avoided with this non-invasive kind of ventilation.
van Kesteren
R G
RG
Academisch Ziekenhuis, Centrum voor Thuisbeademing, Utrecht.
Kampelmacher
M J
MJ
Dullemond-Westland
A C
AC
van Leyden
L W
LW
Verwey-van den Oudenrijn
L P
LP
Douze
J M
JM
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006699:Home Care Services; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000628:therapy; D008297:Male; D008397:Masks; D008875:Middle Aged; D009468:Neuromuscular Diseases / Q000150:complications; D009666:Nose; D011175:Positive-Pressure Respiration / Q000379:methods*; D016262:Postpoliomyelitis Syndrome / Q000150:complications; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*; D012189:Retrospective Studies
Gunstige effecten van nachtelijke nasale positieve-drukbeademing bij 64 patiënten met neuromusculaire aandoeningen; 5 jaar ervaring.