Prostaglandin F2a (PGF2a): an inadequate marker of the vitality of wounds?
We have studied the viability of PGF2a as a vitality marker in skin wounds. Incised vital skin wounds and homolateral control pieces of skin were obtained from 20 autopsies performed at the Institute of Legal Medicine of Coimbra University (Portugal). We have also studied 10 fresh skin samples from the Department of Dermatology of the University Hospital (Granada). Our results show that PGF2a is not suitable for the diagnosis of the vitality of wounds because of its irregular behaviour.
Hernández-Cueto
C
C
Department of Legal Medicine and Toxicology, Faculty of Medicine, University of Granada, Spain.
Vieira
D N
DN
Girela
E
E
Marques
E
E
Calvo
M D
MD
Villalobos
M
M
Oliveira de Sà
F
F
Villanueva
E
E
D015415:Biomarkers; D015237:Dinoprost / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D011180:Postmortem Changes; D011863:Radioimmunoassay; D015203:Reproducibility of Results; D013997:Time Factors; D014947:Wounds and Injuries / Q000378:metabolism / Q000473:pathology*
D015415:Biomarkers; D015237:Dinoprost