Amino acid derivatives from the marine sponge Jaspis digonoxea.
Six heterocycles, bengamide A [1], bengamide B [2], cyclo(L-trans-(4-hydroxyprolinyl)-L-phenylalanine) [4], the functionalized nonene lactone 5, the novel digonazole [6] and cyclo(L-prolinyl-L-tyrosine) [7], previously unreported from marine origin have been isolated from the South African sponge Jaspis digonoxea. The structures of the known compounds and the new digonazole [6] were elucidated primarily by nmr spectroscopy.
Rudi
A
A
School of Chemistry, Tel Aviv University, Israel.
Kashman
Y
Y
Benayahu
Y
Y
Schleyer
M
M
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D011161:Porifera / Q000737:chemistry*
D000596:Amino Acids