Potassium channel openers are likely to be proarrhythmic in the diseased human heart.
Black
S C
SC
Department of Pharmacology, University of Michigan Medical School, Ann Arbor 48109-0626.
Lucchesi
B R
BR
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D016757:Death, Sudden, Cardiac / Q000209:etiology; D004285:Dogs; D006146:Guanidines / Q000494:pharmacology; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D009203:Myocardial Infarction / Q000503:physiopathology*; D017202:Myocardial Ischemia / Q000378:metabolism*; D020110:Pinacidil; D015221:Potassium Channels / Q000187:drug effects*; D014665:Vasodilator Agents / Q000009:adverse effects*
D006146:Guanidines; D015221:Potassium Channels; D014665:Vasodilator Agents; D020110:Pinacidil