[Effects of selenium and DTPA on cadmium excretion in rats].
Fifty-six male wistar rats were selected to study the effects of selenium and DTPA on cadmium excretion. Cadmium levels in urine, feces and tissues of the rats were determined with graphite stove method, and their kidneys were examined pathohistologically. Results showed selenium had stronger effects on cadmium excretion via feces in rats than DTPA did, and combination of both of them showed synergistic effects on it. Also, selenium could accelerate the recovery from kidney injury caused by cadmium, and combination of both of them showed synergism on it.
He
R
R
Department of Environment Health, Hubei Provincial Hygiene and Anti-epidemic Station, Wuhan.
Bao
K G
KG
D000818:Animals; D002104:Cadmium / Q000652:urine*; D002105:Cadmium Poisoning / Q000378:metabolism*; D004357:Drug Synergism; D007668:Kidney / Q000473:pathology; D008297:Male; D004369:Pentetic Acid / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012643:Selenium / Q000494:pharmacology*
D002104:Cadmium; D004369:Pentetic Acid; D012643:Selenium