title: T1 glottic carcinoma involving the anterior commissure.
abstract: This study reviews the records of 56 patients with early glottic carcinoma involving the anterior commissure (T1N0M0) who were treated between 1958 and 1988 at Beilinson Medical Center. Five- and 10-year survival rates were 82% and 60%, respectively. Most failures were local (15 patients). In addition, three patients who were treatment failures had neck lesions (regional failure) and one had lung lesions (distant metastases). All 56 patients received irradiation as the only mode of initial treatment. The effectiveness of irradiation for anterior commissure lesions is therefore evaluated. The study supports previous reports suggesting that glottic carcinoma involving the anterior commissure is associated with a high rate of treatment failure.
authors.affiliation: Department of Otolaryngology, Beilinson Medical Center, Petah Tiqva, Israel.
authors.forename: J
authors.initials: J
authors.lastname: Shvero
authors.forename: T
authors.initials: T
authors.lastname: Hadar
authors.forename: K
authors.initials: K
authors.lastname: Segal
authors.forename: E
authors.initials: E
authors.lastname: Yaniv
authors.forename: G
authors.initials: G
authors.lastname: Marshak
authors.forename: R
authors.initials: R
authors.lastname: Feinmesser
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy* / Q000556:secondary; D005260:Female; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary; D012189:Retrospective Studies; D016019:Survival Analysis; D017211:Treatment Failure