Successful treatment of fetal cardiac arrest by left ventricular exchange transfusion.
A 36-year-old pregnant woman with anti-HPA1a antibodies underwent six fetal platelet concentrate transfusions. During the second, at 28 weeks' gestation, fetal asystole occurred in association with a post-transfusion platelet count of 813 x 10(9)/l. Asystole was reversed by an intracardiac partial exchange transfusion of normal saline for fetal blood, simultaneously reducing fetal plasma viscosity and enabling re-commencement of the fetal circulation.
Rodeck
C H
CH
Department of Obstetrics and Gynaecology, University College London Medical School, UK.
Roberts
L J
LJ
D000328:Adult; D016824:Antigens, Human Platelet / Q000276:immunology; D001792:Blood Platelets / Q000276:immunology; D001805:Blood Transfusion, Intrauterine; D001809:Blood Viscosity; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D005315:Fetal Diseases / Q000209:etiology / Q000628:therapy*; D006323:Heart Arrest / Q000209:etiology / Q000628:therapy*; D006352:Heart Ventricles / Q000196:embryology; D006801:Humans; D039661:Integrin beta3; D007518:Isoantibodies / Q000097:blood; D008297:Male; D008431:Maternal-Fetal Exchange; D017713:Platelet Transfusion / Q000009:adverse effects; D011247:Pregnancy; D011248:Pregnancy Complications; D013921:Thrombocytopenia / Q000196:embryology / Q000276:immunology / Q000628:therapy*
D016824:Antigens, Human Platelet; C061248:ITGB3 protein, human; D039661:Integrin beta3; D007518:Isoantibodies