Preliminary results of three methods for population pharmacokinetic analysis (NONMEM, NPML, NPEM) of amikacin in geriatric and general medicine patients.
Maire
P
P
Department of Pharmacy, Hospital Antoine Charial, Hospices Civils de Lyon, France.
Barbaut
X
X
Girard
P
P
Mallet
A
A
Jelliffe
R W
RW
Berod
T
T
D000368:Aged; D000369:Aged, 80 and over; D000583:Amikacin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001835:Body Weight; D003404:Creatinine / Q000493:pharmacokinetics; D016903:Drug Monitoring; D004360:Drug Therapy, Computer-Assisted; D006801:Humans; D008875:Middle Aged; D008954:Models, Biological; D008956:Models, Chemical; D014018:Tissue Distribution
D000583:Amikacin; D003404:Creatinine