title: [Interleukin-6: friend or enemy? Latest findings on the clinical aspects of IL-6].
abstract: The authors summarize the recent findings obtained in the field of inflammatory cytokines with particular attention on interleukin-6 (IL-6). After a short review of the molecular biology and of the cellular effects of IL-6, the most important clinical relations of IL-6 in hepatic diseases, in non-specific inflammatory bowel diseases (Crohn's disease and ulcerative colitis) and in certain autoimmune diseases are provided. The simultaneous discussion of molecular and clinical data contribute to the understanding of pathomechanisms.
authors.affiliation: Országos Reuma- és Fizioterápiás Intézet, Budapest, II. Belgyógyászati Osztály.
authors.forename: M
authors.initials: M
authors.lastname: Fogarasi
authors.forename: E
authors.initials: E
authors.lastname: Kubala
authors.forename: J
authors.initials: J
authors.lastname: Bíró
authors.forename: A
authors.initials: A
authors.lastname: Falus
authors.forename: E
authors.initials: E
authors.lastname: Nemesánszky
mesh_terms: D001327:Autoimmune Diseases / Q000378:metabolism; D003093:Colitis, Ulcerative / Q000378:metabolism; D003424:Crohn Disease / Q000378:metabolism; D016207:Cytokines / Q000493:pharmacokinetics*; D005767:Gastrointestinal Diseases / Q000378:metabolism*; D006801:Humans; D015850:Interleukin-6 / Q000493:pharmacokinetics*; D008107:Liver Diseases / Q000378:metabolism*; D008967:Molecular Biology
chemical_list: D016207:Cytokines; D015850:Interleukin-6
vernacular_title: Interleukin-6: Ertünk vagy ellenünk? Ujabb eredmények az IL-6 klinikai vonatkozásairól.