title: Gene regulation. Insulating chromatin.
abstract: "Insulator elements" have been identified that define the limits of transcriptionally active chromatin domains, protecting them against the repressive influence of neighboring heterochromatin.
authors.affiliation: Laboratory of Molecular Embryology, NICHHD, NIH, Bethesda, Maryland 20892.
authors.forename: A P
authors.initials: AP
authors.lastname: Wolffe
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000502:physiology / Q000648:ultrastructure; D002843:Chromatin / Q000502:physiology / Q000648:ultrastructure*; D004330:Drosophila / Q000235:genetics; D005127:Eye Color / Q000235:genetics; D006360:Heat-Shock Proteins / Q000235:genetics; D006570:Heterochromatin / Q000502:physiology / Q000648:ultrastructure; D008961:Models, Structural; D012441:Saccharomyces cerevisiae / Q000235:genetics; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin; D006360:Heat-Shock Proteins; D006570:Heterochromatin