XX male syndrome in a cryptorchid stallion.
A bilateral cryptorchid stallion with mild development of mammary glands was identified as an XX male by karyotyping. Necropsy revealed underdeveloped accessory sex organs and hypoplastic, inguinally located testes that were deficient of spermatogonia. Evaluation of routine hormonal profiles (without karyotyping) would have failed to diagnose this syndrome.
Constant
S B
SB
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0136.
Larsen
R E
RE
Asbury
A C
AC
Buoen
L C
LC
Mayo
M
M
D000818:Animals; D003456:Cryptorchidism / Q000235:genetics / Q000662:veterinary*; D012734:Disorders of Sex Development / Q000235:genetics / Q000662:veterinary*; D004967:Estrogens / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000097:blood; D005837:Genitalia, Male / Q000002:abnormalities; D005838:Genotype; D006734:Horse Diseases / Q000235:genetics*; D006736:Horses; D007621:Karyotyping / Q000662:veterinary; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008321:Mammary Glands, Animal / Q000254:growth & development; D010641:Phenotype; D012729:Sex Chromosome Aberrations / Q000235:genetics / Q000662:veterinary*; D013577:Syndrome; D013737:Testis / Q000002:abnormalities; D013739:Testosterone / Q000097:blood; D014178:Translocation, Genetic; D014960:X Chromosome
D004967:Estrogens; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone