title: Neuropeptide Y and cardiovascular regulation.
abstract: Neuropeptide Y is a vasoactive peptide and is widely distributed throughout the central and peripheral nervous systems. Neuropeptide Y is co-released with noradrenaline by perivascular nerve endings. At high concentrations, it has a direct vasoconstrictor effect. In addition, it enhances the vascular effect of various agonists, including noradrenaline and angiotensin II. Moreover, neuropeptide Y has an inhibitory effect on renin secretion. This peptide may have an important role in cardiovascular regulation.
authors.affiliation: Division of Hypertension, Lausanne University Medical School, CHUV, Switzerland.
authors.forename: T
authors.initials: T
authors.lastname: Pedrazzini
authors.forename: H R
authors.initials: HR
authors.lastname: Brunner
authors.forename: B
authors.initials: B
authors.lastname: Waeber
mesh_terms: D000818:Animals; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D009478:Neuropeptide Y / Q000378:metabolism / Q000502:physiology*; D017476:Receptors, Neuropeptide Y / Q000502:physiology
chemical_list: D009478:Neuropeptide Y; D017476:Receptors, Neuropeptide Y