title: Combating drug-resistant pneumococcal infections.
abstract: Penicillin-resistant pneumococcal strains continue to spread. Some strains are also resistant to other antibiotics, including the cephalosporins. Better utilization of the 23-valent pneumococcal vaccine, which covers the serotypes responsible for 90% of pneumococcal infections, is an important step in combating resistance.
authors.affiliation: University of Texas Southwestern Medical School.
authors.forename: J B
authors.initials: JB
authors.lastname: Sanford
mesh_terms: D000368:Aged; D000465:Algorithms; D001428:Bacterial Vaccines; D002439:Cefotaxime / Q000627:therapeutic use*; D018550:Cephalosporin Resistance; D015505:Chest Tubes; D003131:Combined Modality Therapy; D003663:Decision Trees; D003937:Diagnosis, Differential; D018432:Drug Resistance, Multiple; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D010996:Pleural Effusion / Q000209:etiology; D022242:Pneumococcal Vaccines; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D012293:Rifampin / Q000627:therapeutic use; D013296:Streptococcus pneumoniae; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines; D014640:Vancomycin; D002439:Cefotaxime; D012293:Rifampin