Genotoxicity assessment of Rokanol B2 and Rokamid R1.
Two surface-active compounds, Rokanol B2 and Rokamid R1, were examined with three types of screening tests: 1. standard Ames test in vitro using S. typhimurium TA97a, TA98, TA100 and TA102 strains; 2. micronucleus test in vivo; 3. sister chromatid exchange (SCE) on bone marrow cells of Balb C mice. Negative results of the testing, in terms of the effects of activity of both the technical preparations on S. typhimurium cells and bone marrow of Balb C mice, were found for both tested chemicals.
Janik-Spiechowicz
E
E
Department of Carcinogenesis, Teratogenesis and Mutagenesis, Nofer Institute of Occupational Medicine, Lodz, Poland.
Barański
B
B
Dziubałtowska
E
E
Wyszyńska
K
K
Przybojewska
B
B
Chwiałkowska-Liro
W
W
Przondo
J
J
D000818:Animals; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D051379:Mice; D008807:Mice, Inbred BALB C; D015162:Micronucleus Tests; D011092:Polyethylene Glycols / Q000633:toxicity*; D012854:Sister Chromatid Exchange; D018675:Toxicity Tests
D011092:Polyethylene Glycols