title: Biochemical basis of DDT-resistance in Aedes aegypti population from a dengue affected area in Shahjahanpur city.
abstract: Entomological studies conducted in Jalalnagar, Shahjahanpur city, Uttar Pradesh, India, during an outbreak of dengue in 1992, showed that Ae. aegypti mosquitoes were resistant to DDT and had some tolerance to malathion in the adults and the larvae. Biochemical analysis suggested that DDT resistance was related to elevated glutathione s-transferase and tolerance to malathion was due to a little increase in esterase activity. Crosses of DDT-resistant and susceptible strain suggested that resistance was codominant (metabolic type).
authors.affiliation: National Institute of Virology, Pune.
authors.forename: D T
authors.initials: DT
authors.lastname: Mourya
authors.forename: M D
authors.initials: MD
authors.lastname: Gokhale
authors.forename: A C
authors.initials: AC
authors.lastname: Mishra
mesh_terms: D000330:Aedes / Q000201:enzymology* / Q000235:genetics; D000818:Animals; D003634:DDT / Q000494:pharmacology*; D003715:Dengue / Q000453:epidemiology*; D004196:Disease Outbreaks; D007194:India / Q000453:epidemiology; D007305:Insecticide Resistance / Q000235:genetics*; D014504:Urban Health
chemical_list: D003634:DDT