[Effect of jiang-zhi jian-fei yao on gastro-intestinal movement and adipose cell of abdominal wall].
Jiang-Zhi Jian-Fei Yao (JZJFY), an obesity-reducing drug, its active principle is the refined Rhubarb, the mechanism of its obesity-reducing effect was studied. JZJFY was injected intragastrically. The results showed that there was no significant increased of body weight, but a reduction of food intake, prolongation of stomach evacuation time, acceleration of intestinal movement 6 days after medication in rats. Meanwhile the adipose cells in abdominal wall were varied in size, and with Sudan III stain the color of adipose cells was light. Authors suggest that the obesity-reducing effect of JZJFY was relevant to above-mentioned changes.
Jin
H M
HM
Shanghai Medical University.
Jiao
D H
DH
D017667:Adipocytes / Q000187:drug effects*; D000818:Animals; D001067:Appetite Depressants / Q000494:pharmacology / Q000627:therapeutic use; D001835:Body Weight / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D004435:Eating / Q000187:drug effects; D005260:Female; D005746:Gastric Emptying / Q000187:drug effects; D005769:Gastrointestinal Motility / Q000187:drug effects*; D008297:Male; D009765:Obesity / Q000188:drug therapy; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D012250:Rheum
D001067:Appetite Depressants; D004365:Drugs, Chinese Herbal