[Immunogenetic markers in the course of vibration disease].
A total of 276 Russian deep mine workers engaged into perforant boring were examined. HLA phenotype was determined according to the antigens of class 1 and 2. The antigen HLA-DR 5 turned out to associate with the high risk of severe vibration disease development complicated by degeneration and dystrophy of locomotor apparatus of hands. The antigens HLA-B 35, B 40, DR 2 were proved to have protective function and to be markers of higher resistance to the industrial vibration.
Sideltseva
E V
EV
Kolesov
V G
VG
Aleksev
L P
LP
Sideltsev
V V
VV
D000328:Adult; D015415:Biomarkers / Q000097:blood; D015234:HLA-A Antigens / Q000097:blood / Q000276:immunology*; D015235:HLA-B Antigens / Q000097:blood / Q000276:immunology*; D006684:HLA-DR Antigens / Q000097:blood / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D008903:Minerals; D008906:Mining; D009784:Occupational Diseases / Q000097:blood / Q000276:immunology*; D010641:Phenotype; D012307:Risk Factors; D014732:Vibration / Q000009:adverse effects*
D015415:Biomarkers; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006684:HLA-DR Antigens; D008903:Minerals
Immunogeneticheskie markery techeniia vibratsionnoĭ bolezni.