title: Pulmonary circulation evaluation before cavopulmonary connections: the cavopulmonary bypass.
abstract: The outcome of Fontan-type procedures is dependent on several risk factors, among which pulmonary vascular resistances (PVRs) are an important component. Preoperative calculation of PVR entails several potential sources of error, particularly in patients with pulmonary atresia or multiple sources of pulmonary blood flow. In an attempt to develop a reliable test that accurately assesses the hemodynamic patterns of the pulmonary vascular bed before a Fontan procedure, a simulation of Fontan-type circulation was achieved in 13 patients by a partial cardiopulmonary bypass between the main pulmonary artery and both venae cavae (cavopulmonary bypass). During cavopulmonary bypass, pressures and resistances were recorded. Immediately after cavopulmonary bypass, the circulation was converted to standard cardiopulmonary bypass and the cavopulmonary connection was carried out. Preoperative pulmonary vascular resistance indexes were assessed roughly by the arteriovenous oxygen difference in systemic and pulmonary beds. There was no correlation between preoperative and perioperative calculations of pulmonary vascular resistance indexes (r = 0.24; p = not significant). Hemodynamic data available for all patients then were correlated to the early postoperative outcome assessed by a subjective four-point scale. A positive, significant correlation was found with intraoperative PVR (r = 0.90; p < 0.001), indexed PVR (r = 0.90; p < 0.001), and the pulmonary to systemic vascular resistance ratio (r = 0.98; p < 0.0001). Two of 13 patients had a 4-mm fenestration in the atrial baffle. No mortality or morbidity was related to the procedure. The absolute values of PVR and pulmonary vascular resistance indexes were strikingly higher than generally admitted for this type of procedure.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Pediatric Cardiac Surgery, Marie-Lannelongue Hospital, Le Plessis-Robinson, France.
authors.forename: A
authors.initials: A
authors.lastname: Serraf
authors.forename: L
authors.initials: L
authors.lastname: Houyel
authors.forename: F
authors.initials: F
authors.lastname: Nicolas
authors.forename: F
authors.initials: F
authors.lastname: Lacour-Gayet
authors.forename: J
authors.initials: J
authors.lastname: Bruniaux
authors.forename: J
authors.initials: J
authors.lastname: Petit
authors.forename: M S
authors.initials: MS
authors.lastname: Uva
authors.forename: D
authors.initials: D
authors.lastname: Roux
authors.forename: C
authors.initials: C
authors.lastname: Planche
mesh_terms: D000293:Adolescent; D006328:Cardiac Catheterization; D002315:Cardiopulmonary Bypass; D002648:Child; D002675:Child, Preschool; D018729:Fontan Procedure / Q000379:methods*; D006801:Humans; D007223:Infant; D011652:Pulmonary Circulation / Q000502:physiology*; D014655:Vascular Resistance