title: Measurement variability in digital analysis of optic discs.
abstract: The optic disc of nine patients with typical glaucomatous disc damage and ten normal controls has been studied by means of the Optic Disc Analysis program of the Topcon Image-net System. Vertical, horizontal and average cup/disc ratio (VC/D, HC/D, AC/D), disc, cup, rim area (DA, CA, RA), cup volume (CV) have been evaluated and the coefficient of variation (COV) of multiple measurements was calculated. For intra-observer intra-image variability assessment, sterovideographs of each disc were taken once and analyzed 10 times (COV range: 1.39-12.08%). Intra-observer interimage variability was evaluated on eight stereovideographs of each disc taken at one minute intervals (COV range: 1.63-96%). Inter-observer intra-image measurements were taken on each disc by 5 different observer (COV range: 1.28-27.08%).
authors.affiliation: Department of Ophthalmology University of Genoa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Rolando
authors.forename: M
authors.initials: M
authors.lastname: Iester
authors.forename: P
authors.initials: P
authors.lastname: Campagna
authors.forename: L
authors.initials: L
authors.lastname: Borgia
authors.forename: C
authors.initials: C
authors.lastname: Traverso
authors.forename: G
authors.initials: G
authors.lastname: Calabria
mesh_terms: D000328:Adult; D005654:Fundus Oculi; D005902:Glaucoma, Open-Angle / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008875:Middle Aged; D015588:Observer Variation; D009885:Ophthalmology / Q000295:instrumentation; D009898:Optic Disk / Q000473:pathology*; D015203:Reproducibility of Results