Use of a single intrauterine insemination of defrosted cryopreserved sperm for therapeutic donor insemination.
OBJECTIVE
To evaluate the efficacy of a protocol employing defrosted cryopreserved sperm as a single well-timed intrauterine insemination.


METHODS
A retrospective observational study.


METHODS
A university fertility service and a private fertility practice located in small metropolitan areas.


METHODS
All 138 donor sperm recipients (348 cycles) treated on this protocol by the author during a 27 month period were evaluated. All 86 patients (200 cycles) treated using intracervical inseminations bracketing the time of ovulation during the same time period were also evaluated.


RESULTS
A single well-timed intrauterine insemination had an associated pregnancy rate of 13.8% per cycle. In contrast, intracervical inseminations bracketing the time of ovulation had an associated pregnancy rate of 5% per cycle (P < .005).


CONCLUSIONS
A single well-timed intrauterine insemination of defrosted cryopreserved sperm is more efficacious and less expensive than intracervical inseminations bracketing the time of ovulation.
Rose
B I
BI
Fertility and Reproductive Health Services, Lehigh Valley Hospital, Allentown, Pennsylvania.
D015925:Cryopreservation; D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D010060:Ovulation; D011247:Pregnancy; D012189:Retrospective Studies; D012661:Semen; D012662:Semen Preservation / Q000379:methods; D013997:Time Factors