title: Pancolonic disease in cystic fibrosis and high-dose pancreatic enzyme therapy.
abstract: We describe a child with cystic fibrosis who was treated with high-dose pancreatic enzyme replacement therapy and who had a prominent ascending colon stricture with submucosal fibrosis. Unlike prior reported cases, this patient's disease was more extensive, involving the entire colon, and was associated with chylous ascites.
authors.affiliation: Division of Pediatric Gastroenterology and Nutrition, Schneider Children's Hospital, Long Island Jewish Medical Center, New Hyde Park, NY 11040.
authors.forename: M J
authors.initials: MJ
authors.lastname: Pettei
authors.forename: J C
authors.initials: JC
authors.lastname: Leonidas
authors.forename: J J
authors.initials: JJ
authors.lastname: Levine
authors.forename: J D
authors.initials: JD
authors.lastname: Gorvoy
mesh_terms: D002675:Child, Preschool; D002908:Chronic Disease; D002915:Chylous Ascites / Q000209:etiology; D003106:Colon / Q000473:pathology*; D003108:Colonic Diseases / Q000209:etiology*; D003550:Cystic Fibrosis / Q000150:complications* / Q000188:drug therapy; D003967:Diarrhea / Q000209:etiology; D005355:Fibrosis / Q000209:etiology; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D008049:Lipase / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D010184:Pancreatic Extracts / Q000008:administration & dosage / Q000009:adverse effects*; D020799:Pancrelipase
chemical_list: D010184:Pancreatic Extracts; D020799:Pancrelipase; D008049:Lipase