title: The role of parathyroid hormone-related protein in calcium homeostasis in the fetal pig.
abstract: The concentrations of plasma parathyroid hormone-like bioactivity and parathyroid hormone-related protein (1-86) (PTHrP) immunoreactivity were both higher in fetal pigs than in their mothers during the last 3 weeks of gestation. Both activities changed inversely with alterations in the plasma ionized calcium concentration. The data suggest that PTHrP may have a role in calcium homeostasis in the fetal pig, similar to its postulated role in sheep in the stimulation of calcium transport across the placenta.
authors.affiliation: Institute of Biological Sciences, University of Wales Aberystwyth, Penglais.
authors.forename: S K
authors.initials: SK
authors.lastname: Abbas
authors.forename: W A
authors.initials: WA
authors.lastname: Ratcliffe
authors.forename: C
authors.initials: C
authors.lastname: Moniz
authors.forename: M
authors.initials: M
authors.lastname: Dixit
authors.forename: I W
authors.initials: IW
authors.lastname: Caple
authors.forename: M
authors.initials: M
authors.lastname: Silver
authors.forename: A
authors.initials: A
authors.lastname: Fowden
authors.forename: A D
authors.initials: AD
authors.lastname: Care
mesh_terms: D000818:Animals; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D004492:Edetic Acid / Q000494:pharmacology; D005260:Female; D005333:Fetus / Q000187:drug effects / Q000378:metabolism*; D006706:Homeostasis; D006934:Hypercalcemia / Q000139:chemically induced*; D017136:Ion Transport; D010281:Parathyroid Hormone / Q000097:blood*; D044162:Parathyroid Hormone-Related Protein; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011506:Proteins / Q000378:metabolism*; D013552:Swine
chemical_list: D010281:Parathyroid Hormone; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins; D004492:Edetic Acid; D002118:Calcium