["Stunned myocardium"--laboratory curiosity or clinically relevant phenomenon of myocardial failure?].
Reversible contractile dysfunction ("myocardial stunning") now is recognized in laboratory animals as well as in the clinic. The precise mechanism(s) responsible for this transient decrease in myocardial contractility is at present unknown. However substantial body of experimental evidence suggest failure in calcium homeostasis due to free radicals injury and calcium overload in ischemic/reperfused myocardium.
Andres
J
J
Katedry Anestezjologii i Intensywnej Terapii Collegium Medicum Uniwersytetu Jagiellońskiego, Kraków.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D005609:Free Radicals / Q000009:adverse effects; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D017202:Myocardial Ischemia / Q000378:metabolism*; D017682:Myocardial Stunning / Q000209:etiology*
D005609:Free Radicals; D002118:Calcium
"Stunned myocardium"--laboratoryjne kuriozum czy znaczaca klinicznie niewydolność mieśnia sercowego?