title: [Radioimmunologic analysis of trypsin and C-peptide tumor markers for evaluation of treatment efficiency in patients with pancreatic and Vater's ampulla cancer].
abstract: A radioimmunological analysis of the changes in concentration of tumour markers CA 19-9, REA, beta 2-microglobulin, trypsin and C-peptide was carried out in 53 patients with pancreatic cancer and in 14 patients with cancer of the major duodenal papilla before and 7-10 days after the treatment. A control group was comprised of 116 volunteers. The levels of the tumour markers decreased after the combined use of remote radiotherapy and pancreaticoduodenal resection (PDR). After creation of cholecysto-enteroanastomosis and performance of radiotherapy they remained without changes. Exocrine pancreatic function after remote radiotherapy, especially in combination with PDR, was sharply suppressed.
authors.forename: N M
authors.initials: NM
authors.lastname: Putseva
authors.forename: E D
authors.initials: ED
authors.lastname: Chebotareva
authors.forename: V A
authors.initials: VA
authors.lastname: Chernyĭ
authors.forename: I I
authors.initials: II
authors.lastname: Smolanka
mesh_terms: D014670:Ampulla of Vater; D014408:Biomarkers, Tumor / Q000032:analysis*; D002096:C-Peptide / Q000032:analysis*; D018395:CA-19-9 Antigen / Q000032:analysis; D003131:Combined Modality Therapy; D003138:Common Bile Duct Neoplasms / Q000378:metabolism* / Q000628:therapy; D006801:Humans; D016256:Lewis X Antigen / Q000032:analysis; D010190:Pancreatic Neoplasms / Q000378:metabolism* / Q000628:therapy; D000091402:Prohibitins; D011863:Radioimmunoassay; D013514:Surgical Procedures, Operative / Q000379:methods; D013997:Time Factors; D016896:Treatment Outcome; D014357:Trypsin / Q000032:analysis*; D001613:beta 2-Microglobulin / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D002096:C-Peptide; D018395:CA-19-9 Antigen; D016256:Lewis X Antigen; C000717331:PHB2 protein, human; D000091402:Prohibitins; D001613:beta 2-Microglobulin; D014357:Trypsin
vernacular_title: Ispolźovanie radioimmunologicheskogo analiza opukholevykh markerov, tripsina i C-peptida dlia otsenki éffectivnosti lecheniia bolńykh rakom podzheludochnoĭ zhelezy i bolśhogo sosochka dvenadtsatiperstnoĭ kishki.