title: Rapid progression of band-shaped keratopathy with early central localisation in a patient on chronic dialytic treatment.
abstract: This clinical study reports on an unusual start of a band-shaped keratopathy in a patient with diabetic nephropathy on dialytic treatment. The earliest corneal manifestations were centrally located small greyish-white disc-shaped lesions evenly distributed in the interpalpebral area in the left eye. Later a typical peripheral band-shaped keratopathy developed. In the course of the observation period the peripheral keratopathy rapidly spread towards the centre, finally resulting in a complete band-shaped keratopathy in which only the most central original disc-shaped lesions could be identified. Serum calcium and phosphorus concentrations were markedly elevated at the time of the progression of the band-shaped keratopathy but no tertiary hyperparathyroidism was present.
authors.affiliation: Utrecht State University, Department of Ophthalmology, The Netherlands.
authors.forename: N
authors.initials: N
authors.lastname: Klaassen-Broekema
authors.forename: O P
authors.initials: OP
authors.lastname: Van Bijsterveld
mesh_terms: D002114:Calcinosis / Q000209:etiology* / Q000473:pathology; D002118:Calcium / Q000097:blood; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D003928:Diabetic Nephropathies / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000097:blood; D006435:Renal Dialysis; D014792:Visual Acuity
chemical_list: D010758:Phosphorus; D002118:Calcium