Antisense inhibition of CHP100 C-myc expression results in reduced in vitro growth kinetics and loss of in vivo tumorigenesis.
Rosolen
A
A
Department of Pediatrics, University of Padova, Italy.
Toretsky
J
J
Neckers
L
L
D015153:Blotting, Western; D002454:Cell Differentiation; D002455:Cell Division; D015870:Gene Expression; D016259:Genes, myc / Q000235:genetics; D006801:Humans; D007150:Immunohistochemistry; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000235:genetics* / Q000473:pathology; D016271:Proto-Oncogene Proteins c-myc / Q000096:biosynthesis*; D016372:RNA, Antisense / Q000502:physiology*; D014162:Transfection; D014407:Tumor Cells, Cultured
D016271:Proto-Oncogene Proteins c-myc; D016372:RNA, Antisense