Effect of pretreatment of rats with uracil on liver injuries induced by D-galactosamine and allyl alcohol.
Uracil was previously shown by us to be the active principle of Trionyx carapax. In this study, we show that pretreatment with uracil protects rats against hepatic injury induced by allyl alcohol and by D-galactosamine.
Kitajima
S
S
Panapharm Laboratories, Kumamoto, Japan.
Ogawa
N
N
Ariyoshi
T
T
D000433:1-Propanol / Q000633:toxicity; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury; D005688:Galactosamine / Q000633:toxicity*; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008107:Liver Diseases / Q000097:blood / Q000473:pathology / Q000517:prevention & control*; D008297:Male; D020005:Propanols; D051381:Rats; D017208:Rats, Wistar; D014498:Uracil / Q000494:pharmacology*
D020005:Propanols; C006463:allyl alcohol; D014498:Uracil; D005688:Galactosamine; D000433:1-Propanol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase