The antigen presenting capacity of human epidermal Langerhans cells.
Dendritic cells (DC) represent a distinct system of antigen-presenting cells (APC) that function to initiate primary T cell responses and are found as a trace population in both lymphoid and non-lymphoid organs. This paper is focused on some properties of epidermal Langerhans cells (LC), the best characterized non-lymphoid DC. The phenotypic markers of LC are reviewed and their immunological function is presented in view of some recent findings partly obtained in our laboratory.
INSERM U 346, Clinique Dermatologique, Hôpital Edouard-Herriot, Lyon, France.
J
J
Péguet-Navarro
C
C
Moulon
D
D
Schmitt
D017951:Antigen Presentation; D000943:Antigens, Differentiation; D002460:Cell Line; D006241:Haptens; D006801:Humans; D066298:In Vitro Techniques; D007519:Isoantigens; D007801:Langerhans Cells / Q000276:immunology*; D008213:Lymphocyte Activation; D010641:Phenotype; D013601:T-Lymphocytes / Q000276:immunology
D000943:Antigens, Differentiation; D006241:Haptens; D007519:Isoantigens