[The structural and metabolic characteristics of squamous-cell cancer of the larynx].
A quantitative histochemical study of 50 cases of laryngeal squamous-cell carcinoma established differences in the structural-metabolic indices characterized by tumour growth and differentiation. Tumor epithelium exhibited lower activity of the aerobic oxidation enzymes and by a lower content of the nuclear nucleic acids. Differentiation of multilayer epithelium of laryngeal mucous membrane in followed by an increase of the histochemical index dispersion. The dispersion of the structural-metabolic indices is decreasing in the tumor epithelium in the process of differentiation and keratinization. The highest degree of anaplasia is observed in the keratinizing form of carcinoma.
Zhuravleva
T B
TB
Tumekh
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I
D000135:Acid Phosphatase / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000201:enzymology / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000378:metabolism / Q000473:pathology; D004273:DNA, Neoplasm / Q000378:metabolism; D004848:Epithelium / Q000201:enzymology / Q000473:pathology; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007822:Laryngeal Neoplasms / Q000201:enzymology / Q000473:pathology*; D007830:Larynx / Q000201:enzymology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D012334:RNA, Neoplasm / Q000378:metabolism
D004273:DNA, Neoplasm; D012334:RNA, Neoplasm; D007770:L-Lactate Dehydrogenase; D009247:NADH, NADPH Oxidoreductases; D000135:Acid Phosphatase
Strukturno-metabolicheskaia kharakteristika ploskokletochnogo raka gortani.