[Pathological changes in the tissues of the helminth Thominx phasianina after the single administration of tetramisole].
A single dose (0.2 g/kg) of 20% tetramisole granulate to pheasants infected with Thominx phasianina resulted in intestinal helminth elimination in 72 hours. Structural injuries of the helminth cutaneomuscular sac, digestive and sexual system were detected, manifesting 6 h after the injection and reaching their peak 24 h after it. The mitochondria and endoplasmic reticulum of middle intestinal wall, uterus, oviduct epitheliocytes, oogonia, and oocytes of nematodes were found the most sensitive to the drug.
N V
NV
Chebyshev
A V
AV
Shlikas
Iu G
IuG
Alekseevskikh
T G
TG
Suranova
D000818:Animals; D002432:Cecum / Q000469:parasitology; D004353:Drug Evaluation, Preclinical / Q000662:veterinary; D008854:Microscopy, Electron; D009348:Nematoda / Q000187:drug effects* / Q000302:isolation & purification / Q000648:ultrastructure; D009349:Nematode Infections / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary; D011200:Poultry / Q000469:parasitology; D011201:Poultry Diseases / Q000188:drug therapy / Q000469:parasitology; D013773:Tetramisole / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D013773:Tetramisole
Patologicheskie izmeneniia tkaneĭ gel'minta Thominx phasianina posle odnokratnogo vvedeniia tetramizola.