"Early-stage" cirrhotic liver can withstand 75 minutes of inflow occlusion during resection.
The cirrhotic liver is sensitive to prolonged hypoxia. We treated two patients with hepatocellular carcinoma in association with early stage of liver cirrhosis. Resection of segment VII, and segments V plus VII, respectively, was done, with no untoward effects, under 75 minutes of "uninterrupted" portal triad occlusion. The tolerance of the cirrhotic liver to normothermic inflow occlusion is discussed.
Kim
Y I
YI
Department of Surgery I, Oita Medical University, Japan.
Kobayashi
M
M
Aramaki
M
M
Nakashima
K
K
Mitarai
Y
Y
Yoshida
T
T
D006528:Carcinoma, Hepatocellular / Q000150:complications; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D007511:Ischemia; D008099:Liver / Q000098:blood supply*; D008103:Liver Cirrhosis / Q000150:complications / Q000601:surgery*; D008113:Liver Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D013997:Time Factors