Uncomplicated pregnancy and birth of a healthy child by a woman with systemic lupus erythematosus and anti-U1RNP, anti-PCNA/cyclin, anti-dsDNA and anti-phospholipid autoantibodies.
We report the course of a pregnancy of a 21-year-old primipara and primigravida with systemic lupus erythematosus (SLE) and anti-U1RNP, anti-PCNA/cyclin, anti-dsDNA and anti-phospholipid autoantibodies. The pregnancy was normal and a healthy child was born at term. The risks associated with the HLA phenotype of the mother and with these autoantibodies were previously unknown. We present a model for risk assessment in patients with rare laboratory features of SLE.
Department of Dermatology, University of Graz, Austria.
P
P
Auer-Grumbach
H
H
Ramschak
F
F
Kainer
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis*; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D011256:Pregnancy Outcome
D000974:Antibodies, Antinuclear; D017152:Antibodies, Antiphospholipid; D006680:HLA Antigens