[The efficacy of sulbactam-ampicillin in preventing postoperative infections in gynecology and obstetrics. A comparative open study].
An open comparative and multicentric trial was carried out to assess the activity of sulbactam ampicillin combination against no treatment, as a prophylactic agent of post-surgical infection in ob-gyn practice. 100 patients were included in the trial and distributed in two groups. sulbactam/ampicillin 0.5/1.0 g, i.v. was administrated during the surgery and the dose was repeated 6 h. later. No cases of post-surgical infection was detected in the group of sulbactam/ampicillin, while 4 cases were observed in the no treatment group. Sulbactam/ampicillin is an effective and well tolerated antimicrobial agent in the prophylaxis of post-surgical infections.
Ahued Ahued
R
R
Hospital de México, México, D.F.
Leal del Rosal
J A
JA
Rocha del Valle
G
G
Sereno Colo
J A
JA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000667:Ampicillin / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011182:Postoperative Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*; D011292:Premedication; D011446:Prospective Studies; D013407:Sulbactam / Q000627:therapeutic use; D013530:Surgical Wound Infection / Q000517:prevention & control*
C035444:sultamicillin; D000667:Ampicillin; D013407:Sulbactam
Eficacia de Sulbactam/Ampicilina en la profilaxis de infecciones postquirúrgicas en gineco-obstetricia. Estudio abierto comparativo.