The Helmholtz Total Artificial Heart Labtype.
To perform the first experimental tests for validation of a new gear unit concept, the pump chamber, diaphragm, and pusher plate design of an orthotopic electromechanical total artificial heart (TAH) (Helmholtz Labtype) was manufactured. In its early stage of development, it provides some of the most important features of the conceptual final artificial heart. The new gear unit transforms a uniform unidirectional rotational motor movement into translatory pusher plate movements, with resting phase in the end-diastolic position, and the angled pump chamber orientation determines the available space for the motor and gear unit. Furthermore, this labtype provides flexibility with regard to use of different types of structural parts for experimental investigations. The first in vitro test results, obtained with specially designed circulatory mockloops that simulate physiological preload and afterload conditions, are presented. They comprise pressure and flow generation, motor performance, efficiency, and energy consumption. The results prove the feasibility of the new gear unit concept for an electromechanical artificial heart and allow a reliable determination of the necessary performance of the future brushless DC motor for the first in vivo TAH model.
Helmholtz-Institute for Biomedical Engineering, RWTH, Aachen, Germany.
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Kaufmann
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Reul
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Rau
D001794:Blood Pressure; D002302:Cardiac Output; D011211:Electric Power Supplies; D004867:Equipment Design; D005858:Germany; D006354:Heart, Artificial; D018056:Hemorheology; D006801:Humans; D008954:Models, Biological; D013318:Stroke Volume; D013499:Surface Properties