CT and MRI of Gorham syndrome.
Gorham syndrome, also known as massive osteolysis or vanishing bone, is a rare disorder (135 cases reported) leading to extensive loss of bony matrix, replaced by proliferating thin-walled vascular channels. Three histologically proven cases of the disease are reported, including the clinical presentation and modern imaging features with CT (with 3D reconstruction) as well as T1- and T2-weighted MRI. Two cases in young women were located in the pelvis with extensive osteolysis reaching to the acetabulum. The third case in a 2-month-old boy is the youngest case ever reported and involved the humerus. The radiological appearance of the disease is discussed and the importance of the modern imaging methods debated.
Vinée
P
P
Radiologische Universitätsklinik Freiburg, Abteilung Röntgendiagnostik, Germany.
Tanyü
M O
MO
Hauenstein
K H
KH
Sigmund
G
G
Stöver
B
B
Adler
C P
CP
D000077:Acetabulum / Q000000981:diagnostic imaging / Q000473:pathology; D000328:Adult; D005260:Female; D005270:Femur Head / Q000000981:diagnostic imaging / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D006811:Humerus / Q000000981:diagnostic imaging* / Q000473:pathology*; D007223:Infant; D007512:Ischium / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010015:Osteolysis, Essential / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D010384:Pelvic Bones / Q000000981:diagnostic imaging* / Q000473:pathology*; D011630:Pubic Bone / Q000000981:diagnostic imaging / Q000473:pathology; D011856:Radiographic Image Enhancement; D012784:Shoulder Fractures / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods