Two identical copies of IS1246, a 1275 base pair sequence related to other bacterial insertion sequences, enclose the xyl genes on TOL plasmid pWW0.
Two identical direct repeats of a 1275 bp sequence, designated IS1246, encompass the xyl genes, which determine the catabolism of toluene, m- and p-xylenes to central metabolites, on the TOL catabolic plasmid pWW0. IS1246 has a terminal inverted repeat of 12 bp (5'GGGCACCTCGAA3') and contains a major open reading frame of 280 codons. This ORF shows significant homology with ORFs encoded by a number of bacterial insertion sequences from Bacteroides, Neisseria and Escherichia coli.
School of Biological Sciences, University of Wales, Bangor, UK.
B R
BR
Reddy
L E
LE
Shaw
J R
JR
Sayers
P A
PA
Williams
D000595:Amino Acid Sequence; D001439:Bacteroides / Q000235:genetics; D001483:Base Sequence; D016384:Consensus Sequence; D004251:DNA Transposable Elements; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D005810:Multigene Family; D009343:Neisseria / Q000235:genetics; D016366:Open Reading Frames; D010957:Plasmids / Q000235:genetics*; D016958:Pseudomonas putida / Q000235:genetics* / Q000378:metabolism; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping; D017386:Sequence Homology, Amino Acid; D014050:Toluene / Q000378:metabolism; D014992:Xylenes / Q000378:metabolism
D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D014992:Xylenes; D014050:Toluene