Polymorphic expression of an equine T lymphocyte and neutrophil subset marker.
This report describes the further characterization of a group of antibodies which have been assigned to Workshop Cluster 1 by the First International Workshop on Equine Leucocyte Antigens. These antibodies recognize a 22 kDa antigen, which is present on a large subset of T lymphocytes and neutrophils, and on medullary thymocytes. The antigen is polymorphic in its expression, and three equine phenotypes could be identified using the described antibodies. The function and homology of the antigen recognized by these antibodies are unknown.
Lunn
D P
DP
School of Veterinary Medicine, University of Wisconsin, Madison 53706.
Holmes
M A
MA
Duffus
W P
WP
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis*; D000954:Antigens, Surface / Q000276:immunology*; D015415:Biomarkers; D005434:Flow Cytometry / Q000662:veterinary; D006736:Horses / Q000276:immunology*; D016130:Immunophenotyping; D008198:Lymph Nodes / Q000276:immunology; D008970:Molecular Weight; D009504:Neutrophils / Q000276:immunology*; D011110:Polymorphism, Genetic; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface; D015415:Biomarkers