Adenosine deaminase concentration in cerebrospinal fluid during brucella meningitis.
Adenosine deaminase (ADA) activity was measured in the CSF of five patients with confirmed brucella meningitis. The mean enzyme value was 20.00 U/l in the presence of high lymphocyte counts in the CSF. We conclude from this preliminary result that the quick and simple estimation of ADA in CSF could be of great value in the diagnosis of brucella meningitis as the enzyme concentration was high in all five patients. This finding is however not specific and similar results have been reported in other meningitides such as tuberculous meningitis.
Division of Neurology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.
M S
MS
Abduljabbar
D000243:Adenosine Deaminase / Q000134:cerebrospinal fluid*; D002006:Brucellosis / Q000134:cerebrospinal fluid*; D006801:Humans; D018655:Lymphocyte Count; D016920:Meningitis, Bacterial / Q000134:cerebrospinal fluid*
D000243:Adenosine Deaminase