Sphenoid sinus involvement in neuroblastoma.
OBJECTIVE
Malignancy of the sphenoid sinus, especially metastatic involvement, is an extremely rare event at any age and is usually associated with a poor prognosis. We present a case of a 5-year-old boy who underwent allogenic bone marrow transplantation for stage IV neuroblastoma.


METHODS
Three years later, he presented with an isolated lesion, histologically proven to be neuroblastoma, in the sphenoid sinus.


RESULTS
Partial excision of the tumor, followed by chemotherapy and radiotherapy, achieved a remission for 3 years.
Hematology/Oncology Division, Children's Hospital Medical Center, Cincinnati, OH 45229.
M
M
Kohli-Kumar
J
J
Barbosa
R E
RE
Harris
D002675:Child, Preschool; D006801:Humans; D008297:Male; D009447:Neuroblastoma / Q000556:secondary*; D010255:Paranasal Sinus Neoplasms / Q000556:secondary*; D013101:Sphenoid Sinus