[Immunopharmacological analysis of secondary postradiation immunodeficiency].
A model for secondary postradiation immunodeficiency of mice has been used to compare immunocorrective activities of some new immunomodulators (arbidol, cagocel, myelopid, proleukinferon and fragmine) administered at late times (2-3 months) after exposure to a nonlethal radiation dose (4.0 Gy). The highest immunocorrective effect has been shown with fragmine and proleukinferon.
Ivanov
A A
AA
Deshevoĭ
Iu B
IuB
Karpova
N A
NA
Lebedev
V G
VG
Leonenko
I V
IV
Stavrakova
N M
NM
Tazulakhova
E B
EB
Ulanova
A M
AM
Khaustova
L I
LI
Shal'nova
G A
GA
D028341:Activins; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D017985:Dalteparin / Q000627:therapeutic use; D006072:Gossypol / Q000031:analogs & derivatives / Q000627:therapeutic use; D006087:Graft vs Host Reaction / Q000187:drug effects / Q000528:radiation effects; D007111:Immunity, Cellular / Q000187:drug effects / Q000528:radiation effects; D007153:Immunologic Deficiency Syndromes / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D007211:Indoles / Q000627:therapeutic use; D017737:Macrophages, Peritoneal / Q000276:immunology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009842:Oligopeptides; D010455:Peptides / Q000627:therapeutic use; D010587:Phagocytosis / Q000187:drug effects / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000150:complications* / Q000276:immunology; D013997:Time Factors; D013440:Sulfides
D028341:Activins; D000276:Adjuvants, Immunologic; D017985:Dalteparin; D006072:Gossypol; D007211:Indoles; D009842:Oligopeptides; D010455:Peptides; C044147:activin B; C056991:cagocel-1; C048617:myelopeptides; C086979:umifenovir; D013440:Sulfides
Immunofarmakologicheskiĭ analiz vtorichnogo postluchevogo immunodefitsita.