New fatty acid esters of drimane sesquiterpenes from Lactarius uvidus.
This study of lipids of Lactarius uvidus has revealed the presence of new fatty acid esters of uvidin A [2a-d] and drimenol [6a-d]. Treatment of uvidin A [1] with base induced a Favorskii-like rearrangement leading to compounds with a new sesquiterpenoid skeleton. Uvidin A [1] showed insect antifeedant and cytotoxic activities.
Dipartimento di Chimica Organica, Universita' di Pavia, Italy.
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Garlaschelli
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Mellerio
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Vidari
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Vita-Finzi
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology; D001156:Artemia; D001487:Basidiomycota / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D004952:Esters; D005227:Fatty Acids / Q000302:isolation & purification* / Q000494:pharmacology; D005247:Feeding Behavior / Q000187:drug effects; D006801:Humans; D007313:Insecta; D012717:Sesquiterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D004952:Esters; D005227:Fatty Acids; D012717:Sesquiterpenes