Circadian rhythms. ICER is nicer at night (sir!).
Autoregulated expression of a gene encoding multiple transcription factors, including the newly discovered repressor protein, ICER, may play a fundamental role in the regulation of circadian rhythms.
Takahashi
J S
JS
NSF Center for Biological Timing, Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois 60208-3520.
D000818:Animals; D002940:Circadian Rhythm; D051786:Cyclic AMP Response Element Modulator; D004268:DNA-Binding Proteins / Q000096:biosynthesis* / Q000235:genetics; D005786:Gene Expression Regulation; D008322:Mammals; D008954:Models, Biological; D010870:Pineal Gland / Q000378:metabolism / Q000502:physiology*; D012097:Repressor Proteins / Q000096:biosynthesis* / Q000235:genetics
D004268:DNA-Binding Proteins; D012097:Repressor Proteins; D051786:Cyclic AMP Response Element Modulator