Coincidence of vitiligo and Paget's bone disease in a patient.
Paget's bone disease developed in a patient with vitiligo. Scrupulous physical examination excluded further systemic or cutaneous involvement. The immunological workup revealed a reversed CD4/CD8 ratio due to a very low CD4 cell percentage and almost negligible responses to PHA as well as Con A, T cell mitogens. The pathogenic significance of these results, which point to phenotypic and functional T cell defects, is discussed.
Abraham
Z
Z
Department of Dermatology, Reish Policlinic, Haifa, Israel.
Glück
Z
Z
Kinarty
A
A
Lahat
N
N
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D010001:Osteitis Deformans / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography; D014820:Vitiligo / Q000150:complications* / Q000473:pathology