Use of a new sonically cleavable and acido-labile handle for solid-phase peptide amide synthesis.
A new handle usable for solid-phase peptide amide synthesis was designed. New releasing conditions of the peptide using sonication allowed much shorter reaction times at lower TFA concentrations.
Calmes
M
M
Aminoacids and Peptides Laboratory (CNRS), Montpellier University II, France.
Daunis
J
J
David
D
D
Jacquier
R
R
D000577:Amides / Q000138:chemical synthesis*; D000595:Amino Acid Sequence; D006863:Hydrogen-Ion Concentration; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis*; D013010:Sonication
D000577:Amides; D010455:Peptides