[Calcium antagonist enhancement of cardiac resistance to immune damage].
Finoptin in a dose of 0,145 mg/kg prevented cardiomyocytic immune disorders in dogs and rats with cardiogenic shock of immune genesis. In test systems, the drug and nifedipine reduced the immune lysis in the cells by the complement.
Grekova
T I
TI
Kireeva
L A
LA
Shaĭdarova
V A
VA
Trufanova
G I
GI
Bobrova
T V
TV
Kravtsov
V I
VI
Ostretsov
E E
EE
D000818:Animals; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003165:Complement System Proteins / Q000032:analysis / Q000187:drug effects; D004195:Disease Models, Animal; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D005260:Female; D006321:Heart / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects; D007154:Immune System Diseases / Q000209:etiology / Q000276:immunology / Q000503:physiopathology / Q000517:prevention & control*; D008297:Male; D051381:Rats; D012770:Shock, Cardiogenic / Q000209:etiology / Q000276:immunology / Q000503:physiopathology / Q000517:prevention & control*; D013997:Time Factors
D002121:Calcium Channel Blockers; D003165:Complement System Proteins
Povyshenie antagonistami kal'tsiia rezistentnosti serdtsa k immunnomu povrezhdeniiu.