Neonatal lupus erythematosus.
We present a case of neonatal lupus erythematosus (NLE) in a black infant presenting with symmetrical depigmented macules on the face resembling vitiligo. NLE is a rare condition affecting newborn infants of mothers who have connective tissue disease, with or without autoantibodies to extractable nuclear antigens Ro (SS-A), La (SS-B) or ribonucleoproteins. Infants present with cutaneous lesions or congenital heart block or both. The skin lesions are usually annular and erythematous and transient and resemble those of subacute cutaneous lupus erythematosus. The presentation of this patient was therefore striking.
St John's Institute of Dermatology, St Thomas' Hospital, London, UK.
R E
RE
Jenkins
A R
AR
Kurwa
D J
DJ
Atherton
M M
MM
Black
D005148:Facial Dermatoses / Q000151:congenital* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008178:Lupus Erythematosus, Cutaneous / Q000151:congenital* / Q000473:pathology