Posttraumatic seizures.
Posttraumatic epilepsy is one of the most clinically disturbing and, to date, difficult predictive factors associated with head trauma. The risk of developing seizures after head trauma depends on several factors. This article explores the mechanisms and biochemical effects of brain injury, their relationship to developing seizures, antiepileptic prophylaxis, and neuroprotective pharmacologic therapy.
Department of Emergency Medicine, Georgetown University Hospital, Washington, DC.
E M
EM
Dugan
J M
JM
Howell
D000927:Anticonvulsants / Q000627:therapeutic use; D001930:Brain Injuries / Q000150:complications / Q000378:metabolism / Q000628:therapy; D004636:Emergency Service, Hospital; D004834:Epilepsy, Post-Traumatic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D012640:Seizures / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control / Q000628:therapy
D000927:Anticonvulsants