Immunochemiluminometric assay for measurement of thyrotropin in various thyroid disorders.
The measurement of serum TSH concentration by the new ICMA had good precision and was more efficacious than RIA, IRMA and IEMA in distinguishing hyperthyroid patients from euthyroid subjects. Moreover, the measurement of serum TSH by ICMA was less interfered by high concentrations of hCG in sera of patients with trophoblastic disease. However, the assay needs special equipment and the cost is currently higher than other available methods.
Department of Medicine, Faculty of Medicine, Ramathiobodi Hospital, Mahidol University, Bangkok, Thailand.
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Chailurkit
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Rajatanavin
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006063:Chorionic Gonadotropin / Q000097:blood; D005067:Euthyroid Sick Syndromes / Q000097:blood / Q000175:diagnosis; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000175:diagnosis; D007037:Hypothyroidism / Q000097:blood / Q000175:diagnosis; D007118:Immunoassay / Q000379:methods*; D015592:Immunoradiometric Assay; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011863:Radioimmunoassay; D012016:Reference Values; D013959:Thyroid Diseases / Q000097:blood / Q000175:diagnosis*; D013972:Thyrotropin / Q000097:blood*; D014328:Trophoblastic Neoplasms / Q000097:blood / Q000175:diagnosis
D006063:Chorionic Gonadotropin; D013972:Thyrotropin