Medical therapy of inflammatory bowel disease.
Despite advances in pharmacologic approaches, the treatment of ulcerative colitis and Crohn's disease remains a challenge. Prior standards of therapy, sulfasalazine and corticosteroids, are gradually being replaced by mesalamine and alternative immune modulating agents. This article discusses the important pharmacologic properties, mechanisms of action, indications, and complications necessary to apply the expanding armamentarium in clinical practice.
Department of Medicine, University of Chicago Medical Center, Illinois.
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SB
Hanauer
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Baert
D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*