Effect of nephropathogenic infectious bronchitis viruses on renal function in young male broiler chickens.
1. The acute effects of challenge with Australian T-strain infectious bronchitis virus (IBV) on renal function were evaluated, following primary vaccination in 1-d-old male broilers. 2. Challenge with T-strain IBV decreased body weight and induced kidney hypertrophy and kidney asymmetry. 3. Haematocrit was reduced in birds challenged with the Australian T-strain IBV and plasma uric acid was elevated in unvaccinated birds exposed to the IBV challenge. 4. Challenge with T-strain IBV caused significant increases in urinary water losses, accompanied by decreased urine osmolality and increased fractional excretion of sodium, calcium and potassium. 5. Vaccination at 1-d-old with Vic S-strain IBV provided a limited degree of protection against an heterologous challenge with T-strain IBV at 15 d of age.
Department of Biochemistry, Microbiology and Nutrition, Faculty of the Sciences, University of New England, Armidale, New South Wales, Australia.
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Afanador
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Roberts
D000704:Analysis of Variance; D000818:Animals; D001835:Body Weight; D002642:Chick Embryo; D002645:Chickens; D018352:Coronavirus Infections / Q000276:immunology; D006400:Hematocrit; D006984:Hypertrophy; D001351:Infectious bronchitis virus / Q000276:immunology; D007668:Kidney / Q000473:pathology* / Q000503:physiopathology / Q000821:virology; D007677:Kidney Function Tests; D008297:Male; D009929:Organ Size; D014527:Uric Acid / Q000097:blood; D014611:Vaccination
D014527:Uric Acid