The recurrence of recurrent membranous glomerulopathy in a renal transplant recipient: case report and literature review.
We describe the first reported case of a renal transplant patient who had two consecutive recurrences of membranous glomerulopathy in his allografts. Both recurrences were detected 1 year posttransplant. The first transplanted kidney was a none of six antigen match and his second was a four of six antigen match. The patient required a second kidney transplantation within 2 years of detection of the first recurrence. The second allograft has functioned adequately for nearly 4 years after diagnosis. The case and literature review illustrate that membranous glomerulopathy can recur in both poorly and well-matched allografts, that recurrence does not always occur faster in the better-matched kidneys, that cyclosporine does not prevent recurrent disease, and that the course of recurrent membranous glomerulopathy is unpredictable.
Department of Medicine, University of Chicago, Pritzker School of Medicine, IL.
M A
MA
Josephson
B
B
Spargo
D
D
Hollandsworth
J R
JR
Thistlethwaite
D015433:Glomerulonephritis, Membranous / Q000473:pathology; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012086:Reoperation