Delineating peroxisome proliferator action to improve human risk assessment.
Green
S
S
ZENECA Central Toxicology Laboratory, Cheshire, England.
Issemann
I
I
Tugwood
J D
JD
Prince
R A
RA
Aldridge
T C
TC
D042962:Acyl-CoA Oxidase; D000818:Animals; D001483:Base Sequence; D002994:Clofibrate / Q000633:toxicity; D003001:Cloning, Molecular; D004247:DNA / Q000378:metabolism; D004051:Diethylhexyl Phthalate / Q000633:toxicity; D005227:Fatty Acids / Q000494:pharmacology; D006801:Humans; D008099:Liver / Q000187:drug effects; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced; D051379:Mice; D008830:Microbodies / Q000187:drug effects*; D008969:Molecular Sequence Data; D010088:Oxidoreductases / Q000096:biosynthesis / Q000235:genetics; D011401:Promoter Regions, Genetic; D011743:Pyrimidines / Q000633:toxicity; D051381:Rats; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics / Q000378:metabolism; D018168:Receptors, Retinoic Acid / Q000502:physiology; D047488:Retinoid X Receptors; D018570:Risk Assessment; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D014212:Tretinoin / Q000494:pharmacology
D005227:Fatty Acids; D011743:Pyrimidines; D018160:Receptors, Cytoplasmic and Nuclear; D018168:Receptors, Retinoic Acid; D047488:Retinoid X Receptors; D014157:Transcription Factors; D014212:Tretinoin; C006253:pirinixic acid; D004247:DNA; D004051:Diethylhexyl Phthalate; D010088:Oxidoreductases; D042962:Acyl-CoA Oxidase; D002994:Clofibrate