[Trial of evaluating co-existent fungal infection during course of neoplastic disease in patients with lung cancer].
The study was aimed at determination of possible connection between co-existing fungal infection in patients with lung carcinoma with course of neoplastic disease and ability to achieve remission by application of different methods of treatment. The study involved 25 patients with histologically confirmed lung carcinoma. Their sputum and bronchial rinsings were tested mycologically. The tests were performed at the moment of diagnosis of the diseases, during and after treatment. In all patients occurrence and type of Candida infections was investigated. Dynamics of fungal infection was measured by a scale from minimal to very severe. In about 1/3 of patients at the moment of diagnosis of the disease, severe or very severe infection was seen which was dependent of stage of the disease advancement. These preliminary studies seem to indicate that presence of severe or very severe fungal infection is not favourable prognostically and frequently correlates with a progress of neoplastic changes and worse response to treatment.
Klinika Pneumonologii, Instytutu Chorób Wewnetrznych AM w Poznaniu.
H
H
Batura-Gabryel
M
M
Firlik
U
U
Wieczorek
D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D002177:Candidiasis / Q000150:complications* / Q000382:microbiology; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications*; D018288:Carcinoma, Small Cell / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D011379:Prognosis; D013183:Sputum / Q000382:microbiology
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