In vivo anti-tumor activity of synthetic ether lipids is not enhanced by pharmacological modulation of tumor lipid composition.
L
L
Diomede
G
G
Damia
M
M
D'Incalci
L
L
Imperatori
M
M
Algeri
E J
EJ
Modest
M
M
Salmona
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects; D002784:Cholesterol / Q000032:analysis; D004338:Drug Combinations; D005260:Female; D005989:Glycerides / Q000494:pharmacology / Q000627:therapeutic use; D007939:Leukemia L1210 / Q000188:drug therapy / Q000378:metabolism; D016403:Lymphoma, Large B-Cell, Diffuse / Q000737:chemistry / Q000188:drug therapy; D008297:Male; D008560:Membrane Fluidity / Q000187:drug effects; D008563:Membrane Lipids / Q000737:chemistry*; D051379:Mice; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000188:drug therapy; D010713:Phosphatidylcholines / Q000494:pharmacology / Q000627:therapeutic use; D010714:Phosphatidylethanolamines / Q000494:pharmacology / Q000627:therapeutic use; D010742:Phospholipid Ethers / Q000494:pharmacology* / Q000627:therapeutic use; D010743:Phospholipids / Q000032:analysis; D014783:Viscosity
D000970:Antineoplastic Agents; D004338:Drug Combinations; D005989:Glycerides; D008563:Membrane Lipids; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010742:Phospholipid Ethers; D010743:Phospholipids; C026659:edelfosine; D002784:Cholesterol; C046637:neutral lipid, phosphatidylcholine, phosphatidylethanolamine drug combination