[The effect of ionizing radiation on human muscle tissue].
The effect of ionizing radiation (gamma-irradiation of 60Co, doses from 10 Gy to 15 kGy) on human muscle tissue was studied using a biopsy material. Destructive alterations in muscle proteins were observed beginning from the dose of 1.0 kGy: appearance of new protein fractions with molecular mass 68-160 kDa and 18-36 kDa. Resistance of muscle proteins to the trypsin effect was unaltered, while the rate of pronase-induced hydrolysis was slightly increased, about 1.2-fold. Content of water and biomechanical properties of the tissue were unaltered, but the modulus of elasticity was decreased approximately 3-fold after treatment with maximal doses of the ionizing radiation used.
Kondakova
N V
NV
Lisakovskiĭ
S V
SV
Sakharova
V V
VV
Koroleva
O A
OA
Dubinsksia
V A
VA
Nikolaeva
S S
SS
D000328:Adult; D001696:Biomechanical Phenomena; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D006868:Hydrolysis; D008297:Male; D008875:Middle Aged; D009124:Muscle Proteins / Q000378:metabolism / Q000528:radiation effects; D009132:Muscles / Q000502:physiology / Q000528:radiation effects*; D011829:Radiation Dosage
D009124:Muscle Proteins
Vliianie ioniziruiushcheĭ radiatsii na myshechnuiu tkan' cheloveka.