[Fast neutron treatment of osteosarcoma].
Twelve patients with advanced osteosarcoma were treated with fast neutron at the Neutron Therapy Facility, the Hight-Energy Physics Institute, Chinese Academy of Science. Of the 12 patients, 5 were operated after radiotherapy. Three of them received fast neutron alone, and the other 2 with added 60Co. The doses ranged from 660 NcGy to 2 168 NcGy. Pain was relieved and the tumor size decreased in all the treated patients. Only one case was found histologically free of viable tumor cells. Skin reaction was serious and the knee joint function was impaired in all patients.
Department of Orthopedic Surgery, First Hospital of Beijing Medical University.
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Li
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Ma
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D000293:Adolescent; D000328:Adult; D017024:Chemotherapy, Adjuvant; D002648:Child; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005214:Fast Neutrons / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005266:Femoral Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D012516:Osteosarcoma / Q000532:radiotherapy* / Q000601:surgery; D011879:Radiotherapy Dosage
D003037:Cobalt Radioisotopes; D008727:Methotrexate