Cutaneous angiosarcoma as a second malignancy in a lymphedematous leg in a Hodgkin's disease survivor.
Angiosarcoma is a rare and highly malignant neoplasm. Cutaneous angiosarcoma not associated with postmastectomy lymphedema is rare. There are only eight reported cases of development of cutaneous angiosarcoma in a lymphedematous extremity in a patient with preexisting malignancy other than breast cancer. This is the first reported case of development of cutaneous angiosarcoma in a lymphedematous extremity in a Hodgkin's disease survivor. A review of cutaneous angiosarcoma associated with lymphedema and a discussion of the pathogenesis of angiosarcoma are included.
Department of Dermatology, Stanford University Medical Center, Palo Alto, CA 94304.
T T
TT
Kirchmann
B R
BR
Smoller
J
J
McGuire
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology*; D006689:Hodgkin Disease / Q000150:complications / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D008209:Lymphedema / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*