[Luminescent analysis of peripheral blood lymphocytes of patients with chronic diseases of the gastrointestinal system].
Changes in fluorescence intensity of blood lymphocytes of patients with somatic and pretumorous diseases of the gastrointestinal system were detected: fluorescence intensity of lymphocytes fluorochrome-stained with acridine orange was increased in chronic gastric and pancreatitis whereas in patients with pretumorous diseases this parameter could be both increased and decreased. Exposure to an extra stress factor, such as low-dose ionizing radiation, manifested by increased fluorescence intensity of normal subjects' blood lymphocytes, a certain normalization of this parameter in patients with somatic diseases, and an increase of the amplitude of shifts vs. the normal range in patients with pretumor gastrointestinal diseases. Fluorescent analysis of lymphocytes helps integrally assess the functional activity of immunohomeostasis.
Iusupova
L B
LB
D000165:Acridine Orange; D000328:Adult; D005260:Female; D005453:Fluorescence; D005767:Gastrointestinal Diseases / Q000097:blood*; D005770:Gastrointestinal Neoplasms / Q000097:blood; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000097:blood
D000165:Acridine Orange
Liuminestsentnyĭ analiz limfotsitov perifericheskoĭ krovi bol'nykh s khronicheskimi zabolevaniiami zheludochno-kishechnogo trakta.