[Oxygenation of pesticides by pseudomonas aeruginosa as a way for creation of mutagenic compounds].
During biodegradation of pesticides there is a possibility of appearance of toxic metabolites. In this aspect oxygenation of 15 new chemical compounds possessing pesticide activity by Pseudomonas aeruginosa PS6749 was investigated. By application of the Ames test, mutagenicity of appearing products of reaction was investigated. Utilization of oxygen in presence of 11 compounds was found. Metabolites of pesticide IPO 3819-N/3,4-dimethoxybenzylidene/2-hydroxyaniline were mutagenic for a strain of Salmonella typhimurium TA 98. Oxygenation products of remaining compounds did not exhibit mutagenic activity.
Katedra Mikrobiologii, Akademii Medycznej w Lodzi.
J
J
Szarapińska-Kwaszewska
D001673:Biodegradation, Environmental; D009152:Mutagenicity Tests; D009153:Mutagens / Q000378:metabolism; D010084:Oxidation-Reduction; D010575:Pesticides / Q000378:metabolism*; D011550:Pseudomonas aeruginosa / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000187:drug effects
D009153:Mutagens; D010575:Pesticides
Utlenianie pestycydów przez Pseudomonas aeruginosa jako droga tworzenia zwiazków mutagennych.