[Plexiform fibrohistiocytic tumor].
Plexiform fibrohistiocytic tumour has been recently described by Enzinger and Zhang. This is a rare tumour with low grade malignancy which requires large excision. We report two cases, one occurring in a 58-year-old man, presenting a voluminous painless mass of 5 cm on his hand, the other occurring in a 9-year-old boy consulting for a nodule on the chest. On histological examination this dermal hypodermal tumour is characterized by a proliferation of histiocytic-like cells grouped in nodules, where they are associated with multinucleated osteoclastic-like cells and a proliferation of fibroblastic-like cells grouped in fascicles, anastomosing in a plexiform pattern. Immunohistochemistry and ultrastructural aspects are described. Differential diagnosis and histogenesis are discussed.
Sass
U
U
Service de Dermato-Vénéréologie des Hôpitaux Universitaires Saint-Pierre et Brugmann, Bruxelles, Belgique.
André
J
J
Noël
J C
JC
Larsimont
D
D
Olemans
C
C
de Dobbeleer
G
G
Wanet
J
J
Ledoux
M
M
D002648:Child; D003937:Diagnosis, Differential; D006225:Hand; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000601:surgery; D013909:Thorax
Tumeur plexiforme fibrohistiocytaire.