The role of CYP1A enzymes in murine activation of the cooked food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Department of Clinical Pharmacology, Royal Postgraduate Medical School, London, U.K.
K
K
Zhao
A R
AR
Boobis
D S
DS
Davies
N J
NJ
Gooderham
D000818:Animals; D001711:Biotransformation; D002273:Carcinogens / Q000493:pharmacokinetics*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005502:Food; D007093:Imidazoles / Q000493:pharmacokinetics*; D051379:Mice; D008810:Mice, Inbred C57BL; D008862:Microsomes, Liver / Q000201:enzymology
D002273:Carcinogens; D007093:Imidazoles; D003577:Cytochrome P-450 Enzyme System; C049584:2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine