Coaggregation between Porphyromonas gingivalis and mutans streptococci.
Coaggregation occurred between Porphyromonas gingivalis and mutans streptococci. The coaggregation was completely inhibited by L-arginine, N alpha-p-tosyl-L-lysine chloromethyl ketone (TLCK), and a trypsin inhibitor, and weakly inhibited by L-lysine, N-ethylmaleimide, lysozyme, and human whole saliva. The results of heat and proteinase K treatment suggested that a heat-labile proteinaceous substance of P. gingivalis and a heat-stable substance of mutans streptococci may play a role in the coaggregation. Mutans streptococci also aggregated in the presence of the heat-labile factor in the supernatant of P. gingivalis. The aggregation was also inhibited by L-arginine, TLCK, and a trypsin inhibitor.
Department of Oral Microbiology, School of Dentistry, Health Sciences University of Hokkaido, Japan.
A
A
Kamaguchi
H
H
Baba
M
M
Hoshi
K
K
Inomata
D001422:Bacterial Adhesion / Q000187:drug effects; D006358:Hot Temperature; D004364:Pharmaceutical Preparations; D016966:Porphyromonas gingivalis / Q000378:metabolism*; D012463:Saliva; D013295:Streptococcus mutans / Q000378:metabolism*; D013696:Temperature
D004364:Pharmaceutical Preparations