Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors.
Searle Research & Development, Chesterfield, Missouri 63198.
D B
DB
Reitz
J J
JJ
Li
M B
MB
Norton
E J
EJ
Reinhard
J T
JT
Collins
G D
GD
Anderson
S A
SA
Gregory
C M
CM
Koboldt
W E
WE
Perkins
K
K
Seibert
D000284:Administration, Oral; D000818:Animals; D001169:Arthritis, Experimental / Q000188:drug therapy; D016861:Cyclooxygenase Inhibitors / Q000008:administration & dosage / Q000138:chemical synthesis / Q000494:pharmacology*; D003517:Cyclopentanes / Q000008:administration & dosage / Q000138:chemical synthesis / Q000494:pharmacology*; D051379:Mice; D051381:Rats
D016861:Cyclooxygenase Inhibitors; D003517:Cyclopentanes