Vacuolated white blood cells in thalassemia major.
We report a case of thalassemia major in which severe cytoplasmic vacuolization was seen in white blood cells as well as in their precursors. Cytochemical examination of the vacuoles revealed Sudan Black staining. Consequently, we believe that our patient had Jordans' anomaly coexisting with thalassemia major.
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara.
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D002648:Child; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000473:pathology*; D013577:Syndrome; D014617:Vacuoles / Q000473:pathology*; D017086:beta-Thalassemia / Q000097:blood* / Q000235:genetics