Prematurity as a predictor of rickets in Shanghai infants.
The association between prematurity and the prevalence of rickets was examined among 2,227 infants in Shanghai, China. The prevalence of rickets during subjects' first 18 months of life was 6.8% in boys and 4.6% in girls. Pre-term infants were more likely to have rickets than term (> or = 37 weeks gestation) infants, 9.4% versus 5.2%. Birth weight was inversely related to the prevalence of rickets, 15.8% in the < 2,500 g group, 7.1% in the 2,500-2,999 g group, 4.9% in the 3,000-3,499 g group, and 4.2% in the > or = 3,500 g group. After adjusting for covariates including sex, average family income and birth weight, the odds ratio for rickets in pre-term infants was 1.55 compared with term infants. The inverse relationship between birth weight and rickets remained significant after taking sex, family income and pre-term birth into account. In addition, infants of the lower income families were more likely to have rickets than those of higher income families.
Department of Medicine, University of Saskatchewan, Saskatoon, Canada.
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Chen
D001724:Birth Weight; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D005544:Forecasting; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D016017:Odds Ratio; D015995:Prevalence; D012279:Rickets / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors