Concurrent sickle cell hemoglobin C disease and diabetes mellitus: no added risk of proliferative retinopathy?
Of 148 adults with sickle cell hemoglobin C (SC) disease seen at Cook County Hospital and Clinics, Chicago, Illinois, eight patients had coexistent noninsulin-dependent diabetes mellitus. The clinical findings were notable for the paucity of retinal vascular changes. No patient showed proliferative diabetic retinopathy; one patient showed background diabetic retinopathy consisting of a few microaneurysms. Six of the eight patients showed no lesions of proliferative sickle retinopathy. Coexistence of noninsulin-dependent diabetes mellitus and SC disease does not appear to have an additive adverse effect on the presence or severity of proliferative retinopathy in the affected patient.
Koduri
P R
PR
Department of Medicine, Cook County Hospital, Chicago, Illinois 60612.
Patel
A R
AR
Bernstein
H A
HA
D000328:Adult; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003930:Diabetic Retinopathy / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006450:Hemoglobin SC Disease / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors