[Evaluation of the clinical efficacy of azithromycin in acute respiratory infections in children].
Azithromycin activity in vivo has been studied in a group of children with acute respiratory tract infections in order to test the efficacy and tolerability of this antibiotic. The study involved 135 children treated with a single daily 10 mg/kg dose of azithromycin for three consecutive days. Ten days after this treatment 100% of children with otitis media, tracheobronchitis, or rhinosinusitis and 95.9% of children with pharyngo-tonsillitis were cured. Recurrences were never observed. Azithromycin proved remarkably effective for treatment of acute respiratory infections and otitis media in children. Tolerability and therapeutic compliance were excellent.
I Clinica Pediatrica, Università degli Studi di Catania.
G
G
Bottaro
N
N
Rotolo
S
S
Bonforte
R
R
Bucchieri
P
P
De Luca
G
G
Ficarra
A
A
Gulino
P
P
Melillo
A
A
Nicosia
F
F
Prestifilippo
D000208:Acute Disease; D017963:Azithromycin / Q000627:therapeutic use*; D001419:Bacteria / Q000302:isolation & purification; D001991:Bronchitis / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010033:Otitis Media / Q000188:drug therapy; D010612:Pharyngitis / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D012220:Rhinitis / Q000188:drug therapy; D012852:Sinusitis / Q000188:drug therapy; D014069:Tonsillitis / Q000188:drug therapy; D014136:Tracheitis / Q000188:drug therapy
D017963:Azithromycin
Valutazione dell'efficacia clinica dell'azitromicina nelle infezioni acute delle vie respiratorie del bambino.