Cooked mussels contaminated by Dinophysis sp.: a source of okadaic acid.
A method was developed for fractionation and isolation of toxic components present in extracts prepared from Dinophysis-contaminated mussels. The major toxin present in French mussels was identified as okadaic acid by its chromatographic properties and spectral data. Large amounts of mussel tissue (digestive glands and remaining meat) can be treated easily if they are cooked, or cooked and dried and are useful for isolating significant amounts of okadaic acid.
Laboratory of Cellular and Molecular Physiology, University of Caen, France.
J P
JP
Vernoux
S
S
Bansard
J F
JF
Simon
D
D
Nwal-Amang
C
C
Le-Baut
E
E
Gleizes
J M
JM
Fremy
M C
MC
Lasne
D000818:Animals; D049872:Bivalvia; D002273:Carcinogens / Q000302:isolation & purification* / Q000633:toxicity; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D003296:Cooking; D004988:Ethers, Cyclic / Q000302:isolation & purification* / Q000633:toxicity; D005506:Food Contamination; D005511:Food Handling / Q000379:methods; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D019319:Okadaic Acid
D002273:Carcinogens; D004988:Ethers, Cyclic; D019319:Okadaic Acid