Occult dysraphism in adulthood: clinical course and management.
We present a series of 23 patients with dysraphic malformations and adult onset of symptoms (4 meningoceles, 19 spinal hamartomas). Mean age at presentation was 39 +/- 21 years (range 23-67 years). Patients were followed up for a mean period of 19 months (range 0.5-68 months). Only patients with progressive neurological disease were operated on (3 meningoceles and 16 spinal hamartomas). The remaining patients were treated conservatively and continue to be observed clinically. Two of three patients operated for meningoceles improved without recurrence of symptoms. Patients with spinal hamartomas could be divided into two groups according to their main symptom: paraparesis (group A, n = 8) or pain (group B, n = 11). Malformations in group B were typically associated with a tethered cord and tended to be more complex than in group A. The majority of patients in group A showed better long-term results than patients in group B, due to their considerably lower rate of recurrence.
Klekamp
J
J
Abteilung für Neurochirurgie, Nordstadt-Krankenhaus, Medizinische Hochschule Hannover, Germany.
Raimondi
A J
AJ
Samii
M
M
D000328:Adult; D000368:Aged; D003884:Dermoid Cyst / Q000175:diagnosis / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006222:Hamartoma / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008067:Lipoma / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008588:Meningocele / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis; D012008:Recurrence; D016136:Spina Bifida Occulta / Q000175:diagnosis* / Q000601:surgery; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000601:surgery