A failure mechanism of Leeds-Keio ligaments.
From our experience with the Leeds-Keio artificial ligament at Bolton Hospitals we report the histology from three cases in which the new ligament was demonstrated to have failed in response to trivial injury, after an initially successful anterior cruciate replacement. The histology showed fragmentation of graft material associated with a chronic inflammatory response in the new ligament. A chronic inflammatory response occurs as a result of fragmentation of the Dacron fibres; and once established, inhibits production of the neoligament, thus dooming it to failure.
Ryan
W G
WG
Department of Orthopaedic Surgery, Bolton Royal Infirmary, Lancashire, UK.
Banks
A J
AJ
D000328:Adult; D016118:Anterior Cruciate Ligament / Q000473:pathology*; D001187:Artificial Organs; D001265:Athletic Injuries / Q000473:pathology / Q000601:surgery*; D005549:Foreign-Body Reaction / Q000473:pathology*; D006801:Humans; D008297:Male; D011091:Polyesters; D011475:Prosthesis Failure
D011091:Polyesters