[Epidemic of aseptic meningitis with echovirus type 6 in Gifu Prefecture in 1992].
From January to December in 1992, an epidemic of aseptic meningitis occurred in Gifu Prefecture in children. Epidemiological, virological and serological investigations were performed. The results are as follows: 1) Cases involved ranged from 0 to 15 years of age, and 75.9% of them were in the 3 to 7 year of age group. 2) Six types of viruses were isolated from 73 of 108 cases (67.6%), and the Echovirus 6 was recovered from 68 cases (93.2%). 3) In 1992 by the cross neutralizing test between the prototype and isolated strains of Echovirus 6, a remarkable antigenic variation was not found. 4) In serological studies, the positive rates of neutralizing antibodies to Echovirus 6 in infant sera aged 0-9 years in 1992-1993, was 41.1%. The highest positive rates of antibodies was in the 5 year age group.
Gifu Prefectural Health and Environment Research Center.
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Miwa
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D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004458:Echovirus 6, Human / Q000302:isolation & purification*; D004457:Echovirus Infections; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008582:Meningitis, Aseptic / Q000453:epidemiology* / Q000821:virology; D008587:Meningitis, Viral / Q000453:epidemiology* / Q000821:virology