[Thyrotoxic crisis after exposure to iodine. A case with fatal outcome].
A 78-year-old woman is presented with a multinodular toxic goiter and euthyroidism under continuous low-dose treatment with antithyroid drugs. A period of hyperthyroidism had been documented 3 years previously. In the preoperative management, prior to resection of a benign ovarian tumour, an intravenous urogram was performed. Perchlorate was given for thyroid protection. One day after surgery the clinical signs of thyroid storm were observed. Immediately, high-dose antithyroid drug therapy was started. Nevertheless, the patient died of acute cardiovascular failure 3 days later. This case report focuses on the risk of thyroid storm following iodine excess in the presence of relevant functional thyroid autonomy without adequate thyroid protection.
Blattmann
H
H
Abteilung Nuklearmedizin, Radiologische Universitätsklinik Freiburg.
Reinhardt
M
M
Schümichen
C
C
Moser
E
E
D000368:Aged; D003537:Cystadenoma / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D006044:Goiter, Nodular / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007044:Hysterectomy; D007455:Iodine / Q000009:adverse effects*; D008713:Methimazole / Q000008:administration & dosage*; D010051:Ovarian Neoplasms / Q000601:surgery*; D010472:Perchlorates / Q000008:administration & dosage; D011183:Postoperative Complications / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D017670:Sodium Compounds / Q000008:administration & dosage; D013958:Thyroid Crisis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D013960:Thyroid Function Tests; D014567:Urography
D010472:Perchlorates; D017670:Sodium Compounds; D008713:Methimazole; D007455:Iodine; C031068:sodium perchlorate
Thyreotoxische Krise nach Jodexposition. Ein Fall mit letalem Ausgang.