Plasma alpha 1-acid glycoprotein concentration in broilers: influence of age, sex and injection of Escherichia coli lipopolysaccharide.
1. The influence of age, sex and injection of Escherichia coli lipopolysaccharide (LPS) on the plasma concentration of alpha-1 acid glycoprotein (AGP) was determined in broilers using the single radial immunodiffusion method. 2. Plasma AGP concentration increased in the 3 d after hatching, and then stabilised at 240 +/- 33 micrograms/ml up to 14 d of age. 3. No sex-related differences in plasma AGP concentration were observed up to 6 weeks of age. 4. A single injection of 900 micrograms LPS per chick resulted in a 5-fold increase in AGP concentration compared with that in saline-injected chicks. Multiple injections of LPS (200 micrograms/chick every 2 d for 14 d) caused only a 50% increase in AGP concentration.
Department of Animal Science, Tohoku University, Sendai, Japan.
K
K
Takahashi
N
N
Kaji
Y
Y
Akiba
K
K
Tamura
D000375:Aging / Q000097:blood*; D000818:Animals; D002645:Chickens / Q000097:blood*; D004926:Escherichia coli; D005260:Female; D008070:Lipopolysaccharides / Q000633:toxicity*; D008297:Male; D009961:Orosomucoid / Q000187:drug effects / Q000378:metabolism*; D012727:Sex Characteristics
D008070:Lipopolysaccharides; D009961:Orosomucoid