Erythromycin in neonatal postoperative intestinal dysmotility.
The motilin agonist erythromycin was used successfully in four infants receiving prolonged parenteral nutrition for severe intestinal dysmotility after gastrointestinal surgery. In a further child with a neuropathic intestinal pseudo-obstruction erythromycin induced a striking small intestinal manometric response, but was without effect in a child with an intestinal myopathy.
Simkiss
D E
DE
Children's Hospital, Birmingham.
Adams
I P
IP
Myrdal
U
U
Booth
I W
IW
D004917:Erythromycin / Q000627:therapeutic use*; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007410:Intestinal Diseases / Q000188:drug therapy*; D007421:Intestine, Small / Q000503:physiopathology; D007583:Jejunum / Q000002:abnormalities; D008365:Manometry; D011183:Postoperative Complications / Q000188:drug therapy* / Q000503:physiopathology; D013270:Stomach / Q000002:abnormalities
D004917:Erythromycin