Hemoglobin C disease in infancy and childhood.
We reviewed the clinical course, physical findings, and hematologic values in 16 pediatric patients with hemoglobin C disease, all but one identified by a newborn hemoglobinopathy screening program. The patients had a few symptoms or physical findings. Height and weight percentiles were normal. Patients typically had a mild hemolytic anemia characterized by microcytosis and target cells.
Olson
J F
JF
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710.
Ware
R E
RE
Schultz
W H
WH
Kinney
T R
TR
D000293:Adolescent; D001827:Body Height; D001835:Body Weight; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D005293:Ferritins / Q000097:blood; D005500:Follow-Up Studies; D006445:Hemoglobin C Disease / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010808:Physical Examination; D017701:Reticulocyte Count; D017086:beta-Thalassemia / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology
D006454:Hemoglobins; D005293:Ferritins