Immunoglobulin receptors. Handicapping the immune response.
Gene targeting experiments that "knock out" the expression of cellular Fc receptors for immune complexes have confirmed previous assumptions about the receptors' function but have also revealed some surprises.
Metzger
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National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892.
D000818:Animals; D002460:Cell Line; D002522:Chlorocebus aethiops; D005796:Genes; D006969:Hypersensitivity, Immediate / Q000276:immunology; D007073:Immunoglobulin E / Q000276:immunology; D007141:Immunoglobulin Fc Fragments / Q000378:metabolism; D007152:Immunologic Capping; D008407:Mast Cells / Q000276:immunology; D051379:Mice; D018345:Mice, Knockout; D011485:Protein Binding; D011961:Receptors, Fc / Q000737:chemistry / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D015398:Signal Transduction
D007141:Immunoglobulin Fc Fragments; D011961:Receptors, Fc; D007073:Immunoglobulin E