[Pseudomonas microcins: characterization and effect of iron concentration].
Antibacterial substances were found in Pseudomonas, they were heat and trypsin resistant, molecular weight less than 10,000 daltons, produced in minimal media, optimum pH 7.0. Methionine and glycine inhibited them; other amino acids produced less antagonistic effect. An inverted relationship between susceptibility to microcin and Fe3+ concentration was observed in experiments with iron-depleted strains. Pseudomonas was sensitive to its own microcin in iron-free medium; this is an important finding in the study of the immunity of microcin-producing strains.
Universidad Nacional de Río Cuarto, Facultad de Ciencias Exactas, Fisico-químicas y Naturales, Departamento de Microbiología e Inmunología, Córdoba, Argentina.
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Barberis
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Pájaro
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Albesa
D001430:Bacteriocins / Q000037:antagonists & inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D003470:Culture Media; D005998:Glycine / Q000494:pharmacology; D006358:Hot Temperature; D007501:Iron / Q000494:pharmacology; D008715:Methionine / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008970:Molecular Weight; D011549:Pseudomonas / Q000187:drug effects / Q000378:metabolism*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000187:drug effects
D001430:Bacteriocins; D003470:Culture Media; C020411:microcin; D008715:Methionine; D007501:Iron; D005998:Glycine
Microcinas en Pseudomonas: caracterización y efecto de la concentración de fierro.