Acute bone marrow toxicity and pancytopenia following exposure to lead chromate, xylene, and ethylbenzene in a degloving injury.
A case of unique acute bone marrow toxicity and pancytopenia following subcutaneous exposure to lead chromate, xylene, and ethylbenzene in a previously healthy patient is reported. The patient sustained an extensive degloving injury to his lower extremity. The wound was contaminated with traffic paint containing lead chromate pigment along with a large volume of xylene and ethylbenzene solvent. Consequences of the patient's clinical course and management of degloving injuries are discussed.
Erickson
T
T
University of Illinois at Chicago, Program in Emergency Medicine, Chicago 60612.
Amed
V
V
Leibach
S J
SJ
Bushnik
P
P
Saxon
A
A
Hryhorczuk
D O
DO
Knopse
W H
WH
D000063:Accidents, Traffic; D001555:Benzene Derivatives / Q000506:poisoning*; D001853:Bone Marrow / Q000187:drug effects*; D002840:Chromates / Q000633:toxicity*; D006801:Humans; D007854:Lead / Q000633:toxicity*; D007869:Leg Injuries / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases; D010198:Pancytopenia / Q000209:etiology*; D014992:Xylenes / Q000506:poisoning*
D001555:Benzene Derivatives; D002840:Chromates; D014992:Xylenes; D007854:Lead; C031895:lead chromate; C004912:ethylbenzene