Rate of occurrence of Helicobacter pylori in patients with gastroduodenal pathology: pilot research.
In an attempt to establish the etiologic role of Helicobacter pylori (H. pylori) in gastric and/or duodenal pathology, 169 patients were tested and compared with a control group of 25 healthy subjects, for a total of 194 subjects. Data on sex, age, familiarity, smoking, coffee and alcohol habits were collected and each patient underwent histological, microbiological and immunological tests. 80 (41.2%) subjects were found positive to H. pylori. This bacterium was detected in 53.3% of patients with gastric ulcer while IgG were found in 86.7%; in 50% of patients with chronic atrophic gastritis while IgG were detected in 80%; in 48.5% of patients with duodenal ulcer while IgG were found in 87.9%; in 41.8% of patients with superficial chronic gastritis while IgG were detected in 80.2%. In the control group of healthy patients H. pylori was found in 28% of patients while IgG were detected in 62.5%. The results do not confirm a direct clear-cut correlation between this microorganism and the pathologies studied.
Nicosia
R
R
Clinical Microbiology II, Faculty of Medicine, University La Sapienza, Rome, Italy.
Pustorino
R
R
Sessa
R
R
Santino
I
I
Busicchio
P
P
D'Ambra
G C
GC
Di Paola
M
M
Del Piano
M
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood; D001706:Biopsy; D004381:Duodenal Ulcer / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D004724:Endoscopy; D005260:Female; D005756:Gastritis / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D005767:Gastrointestinal Diseases / Q000453:epidemiology* / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D016481:Helicobacter Infections / Q000150:complications / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D010865:Pilot Projects; D012307:Risk Factors; D012384:Rome / Q000453:epidemiology
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G