Randomized prospective intervention study of human cervical wart virus infection.
Between February, 1988, and January, 1991, 222 women with histologically proven cervical wart virus infection without dysplasia were randomized to be managed by 1 of 4 protocols. Group 1 acted as control, Group 2 were asked to use condoms for 6 months, Group 3 underwent local ablative therapy and Group 4 were asked to use condoms after ablative therapy. Assessment at 2 and 3 years of follow-up showed no statistically significant superiority for treatment over observation. Defaulters from follow-up were over 50% by the completion of the study.
Royal Women's Hospital, Brisbane, Queensland.
B G
BG
Ward
I L
IL
Thomas
D000328:Adult; D017280:Condoms; D003218:Condylomata Acuminata / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D013997:Time Factors; D002577:Uterine Cervical Diseases / Q000503:physiopathology / Q000628:therapy*; D002578:Uterine Cervical Dysplasia / Q000503:physiopathology