Long term administration of testosterone on ascorbic acid metabolism in castrated rats.
Orchidectomy caused a significant decrease in the concentration of ascorbic acid and ascorbic acid-2-sulphate in tissues while administration of testosterone to these animals reverses this effect. Concentration of ascorbic acid in liver in experimental groups correlates with the activity of L-qualano-lactone oxidase and dehydroascorbatase in this tissue.
Department of Biochemistry, University of Kerala Kariavattom, Trivandrum, India.
K T
KT
Kumari
V P
VP
Menon
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Leelamma
D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D008297:Male; D009919:Orchiectomy; D051381:Rats; D017207:Rats, Sprague-Dawley; D013739:Testosterone / Q000494:pharmacology*; D013997:Time Factors
D013739:Testosterone; D001205:Ascorbic Acid