[Screening for ovarian cancers: critical analysis].
The ovarian cancers have a low incidence rate and a high mortality rate mainly due to a late diagnosis. The potential value of ultrasonography and measurements of tumour associated markers to detect early ovarian cancer suggest the interest of a screening strategy. The analysis of the conditions for efficacy of a such screening program, of the predictive values of ultrasonography and tumour associated markers measurements and of the results of preliminary studies does not confirm on a rational basis the potential interest of screening strategies.
Service de gynécologie-obstétrique, Hôpital Bichat, Paris.
G
G
Pennehouat
J N
JN
Gugliemina
M
M
Naouri
J
J
Créquat
J M
JM
Bouret
Y
Y
Thébault
P
P
Madelenat
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D018394:CA-125 Antigen / Q000097:blood; D002423:Cause of Death; D005260:Female; D006801:Humans; D015994:Incidence; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D010808:Physical Examination; D010865:Pilot Projects; D012680:Sensitivity and Specificity; D015996:Survival Rate; D014626:Vaginal Smears
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen
Dépistage des cancers de l'ovaire: analyse critique.