Environmental regulation of alpha-haemolysin expression in Escherichia coli.
The effect of osmolarity, temperature and anaerobiosis on the expression of Escherichia coli alpha-haemolysin was investigated. Low osmolarity of the culture medium, growth at high temperature (37 degrees C) and anaerobiosis increase haemolysin production in E. coli cells harbouring the haemolytic plasmid pHly152 as well as in haemolytic strains isolated from urinary-tract infections.
Departamento de Microbiología, Facultad de Biología, Universidad de Barcelona, Spain.
M
M
Mouriño
F
F
Muñoa
C
C
Balsalobre
P
P
Diaz
C
C
Madrid
A
A
Juarez
D000693:Anaerobiosis; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics; D001427:Bacterial Toxins / Q000096:biosynthesis*; D001483:Base Sequence; D004926:Escherichia coli / Q000378:metabolism* / Q000472:pathogenicity; D029968:Escherichia coli Proteins; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology*; D006460:Hemolysin Proteins / Q000096:biosynthesis* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D009994:Osmolar Concentration; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D013696:Temperature; D014551:Urinary Tract / Q000382:microbiology
D001426:Bacterial Proteins; D001427:Bacterial Toxins; D029968:Escherichia coli Proteins; D006460:Hemolysin Proteins; C036507:Hlya protein, E coli; D011993:Recombinant Fusion Proteins