Acute bone marrow toxicity and pancytopenia following exposure to lead chromate, xylene, and ethylbenzene in a degloving injury.
A case of unique acute bone marrow toxicity and pancytopenia following subcutaneous exposure to lead chromate, xylene, and ethylbenzene in a previously healthy patient is reported. The patient sustained an extensive degloving injury to his lower extremity. The wound was contaminated with traffic paint containing lead chromate pigment along with a large volume of xylene and ethylbenzene solvent. Consequences of the patient's clinical course and management of degloving injuries are discussed.
University of Illinois at Chicago, Program in Emergency Medicine, Chicago 60612.
T
T
Erickson
V
V
Amed
S J
SJ
Leibach
P
P
Bushnik
A
A
Saxon
D O
DO
Hryhorczuk
W H
WH
Knopse
D000063:Accidents, Traffic; D001555:Benzene Derivatives / Q000506:poisoning*; D001853:Bone Marrow / Q000187:drug effects*; D002840:Chromates / Q000633:toxicity*; D006801:Humans; D007854:Lead / Q000633:toxicity*; D007869:Leg Injuries / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases; D010198:Pancytopenia / Q000209:etiology*; D014992:Xylenes / Q000506:poisoning*
D001555:Benzene Derivatives; D002840:Chromates; D014992:Xylenes; D007854:Lead; C031895:lead chromate; C004912:ethylbenzene