[Studies on the antifertility constituents of Marsdenia oreophila].
A new pregnane glycoside, marsdeoreophiside B was isolated from the stems of Marsdenia oreophila (Asclepiadeaece). The structure was elucidated by means of chemical and spectrometric analysis as 12-O-cinnamyldihydrosarcostin-3-O-beta-D-glucopyranosyl (1-->4)-O-3-O-methyl-6-deoxy-beta-D-allopyranosyl(1-->4)-O-beta-D- oleandropyranosyl (1-->4)-O-beta-D-cymaropyranoside. It showed significant antifertility activity in rats.
Family Planning Research Institute, Tongji Medical University, Wuhan.
Y E
YE
Zhang
J L
JL
Ruan
W P
WP
Ding
D000019:Abortifacient Agents / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D005260:Female; D015394:Molecular Structure; D051381:Rats; D017207:Rats, Sprague-Dawley
D000019:Abortifacient Agents; D004365:Drugs, Chinese Herbal