Eradication of Viridans streptococci from the amniotic cavity with transplacental antibiotic treatment.
We report a case of eradication of Viridans streptococci from the amniotic cavity in a patient with preterm labor and intact membranes by transplacental antibiotic treatment. Following this modality of treatment, preterm labor was arrested and the pregnancy continued uneventfully until normal term delivery. We suggest that transplacental antibiotic treatment should be seriously considered as part of the medical armamentarium for treatment of patients with preterm labor and microbial invasion of the amniotic cavity.
Mazor
M
M
Department of Obstetrics and Gynecology, Soroka Medical Center of Kupat Holim, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Chaim
W
W
Hershkowitz
R
R
Wiznitzer
A
A
D000284:Administration, Oral; D000328:Adult; D000658:Amoxicillin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D000667:Ampicillin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D002821:Chorioamnionitis / Q000188:drug therapy*; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D008431:Maternal-Fetal Exchange; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D011247:Pregnancy; D013290:Streptococcal Infections / Q000188:drug therapy*
D000667:Ampicillin; D000658:Amoxicillin