[Exogenous reinfection with Mycobacterium tuberculosis caused by nosocomial transmission by a patient with AIDS].
A 55-year-old AIDS patient relapsed with tuberculosis as a result of exogenous reinfection, 1.5 years after a prior diagnosis of tuberculosis, for which he had been treated. He was reinfected after exposure to another AIDS patient, a 25-year-old man with tuberculosis, when they were hospitalized together during 5 days. The diagnosis of tuberculosis in the latter patient was delayed because the clinical picture was obscured by another infection. Reinfection and nosocomial transmission were demonstrated by analysis of the restriction-fragment-length polymorphism patterns on serial isolates of Mycobacterium tuberculosis. Increased alertness to tuberculosis, especially among HIV-infected persons, and implementation of effective infection control precautions are important in the prevention of nosocomial transmission.
Gemeentelijke Geneeskundige en Gezondheidsdienst, afd. Tuberculosebestrijding, Amsterdam.
H
H
van Deutekom
F A
FA
Claessen
J G
JG
Koeleman
P E
PE
de Haas
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage; D003428:Cross Infection; D004269:DNA, Bacterial / Q000302:isolation & purification; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000382:microbiology / Q000635:transmission
D000995:Antitubercular Agents; D004269:DNA, Bacterial
Exogene reïnfectie met Mycobacterium tuberculosis door nosocomiale transmissie bij een patiënt met AIDS.