Antibacterial activity of Actisorb Plus, Actisorb and silver nitrate.
Activated Charcoal Cloth with silver (Actisorb Plus) and solutions of silver nitrate, but not Actisorb (Activated Charcoal Cloth without silver), demonstrated antibacterial activity against Gram-negative and Gram-positive bacteria. This activity was unimpaired in the presence of plasma. Sodium thioglycollate was an effective neutralizer of Actisorb Plus and of silver nitrate, indicating that the release of silver from Actisorb Plus contributed to the antibacterial activity of the dressing.
Welsh School of Pharmacy, University of Wales College of Cardiff, UK.
J R
JR
Furr
A D
AD
Russell
T D
TD
Turner
A
A
Andrews
D002606:Charcoal / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D012835:Silver Nitrate / Q000494:pharmacology*
D002606:Charcoal; D012835:Silver Nitrate