Responses of atrial natriuretic peptide and other fluid regulating hormones to long distance swimming in the sea.
The plasma hormonal response following a swimming competition in the sea (18 km) was evaluated in 12 top level male endurance swimmers. At the end of the effort, while plasma renin activity (PRA) and aldosterone concentration (ALDO) were unchanged, a significant increase in plasma atrial natriuretic peptide (ANP) and antidiuretic hormone (ADH) concentrations were recorded. These changes were associated with a decrease in haematocrit and an increase in Na+ and Cl- plasma concentrations. The individual variations of ANP (difference between the final and initial concentrations) were inversely correlated with the corresponding individual variations of PRA and ADH. The results suggest that, during prolonged swimming, ANP may exert an inhibitory effect on the PRA-ALDO axis and have a modulatory role with regard to ADH secretion.
Istituto di Fisiologia Umana, Università degli Studi di Siena, Italy.
M
M
Bonifazi
E
E
Bela
G
G
Carli
L
L
Lodi
C
C
Lupo
E
E
Maioli
G
G
Martelli
M
M
Paghi
A
A
Ruspetti
A
A
Viti
D000293:Adolescent; D000328:Adult; D000450:Aldosterone / Q000097:blood*; D009320:Atrial Natriuretic Factor / Q000097:blood*; D002712:Chlorides / Q000097:blood; D006400:Hematocrit; D006801:Humans; D008297:Male; D005082:Physical Exertion / Q000502:physiology; D012083:Renin / Q000097:blood*; D012964:Sodium / Q000097:blood; D013550:Swimming / Q000502:physiology*; D014667:Vasopressins / Q000097:blood*
D002712:Chlorides; D014667:Vasopressins; D000450:Aldosterone; D009320:Atrial Natriuretic Factor; D012964:Sodium; D012083:Renin