[Renal tubular acidosis (type 2) in a Friesian mare].
A 2-year-old Friesian mare was examined because she had been sluggish for a few weeks. Blood biochemistry showed that concentrations of creatinine (136 mumol.L-1) and urea nitrogen (6.1 mmol.L-1) in plasma were within their normal limits. Severe metabolic acidosis was apparent; the venous pH was 7.154 and the bicarbonate concentration was 13 mmol.L-1. The base excess amounted to -15.3 mmol.L-1 and the venous pCO2 measured 5.1 kPa. Plasma sodium was normal (135 mmol.L-1) and plasma chloride (113 mmol.L-1) was slightly elevated, but there was a hypokalaemia (2.9 mmol.L-1). The urine had a specific gravity of 1.040 and a pH of 5. These findings indicated type 2 renal tubular acidosis. The blood values returned to normal 3 days after treatment with sodium bicarbonate as a 4.2 per cent solution (3.2 mol in total) and additional bicarbonate (125 g) and potassium chloride (100 g) administered orally.
Vakgroep Inwendige Ziekten en Voeding der Grote Huisdieren, Faculteit Diergeneeskunde, Universiteit Utrecht.
J H
JH
van der Kolk
D000141:Acidosis, Renal Tubular / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D001639:Bicarbonates / Q000627:therapeutic use; D005260:Female; D006734:Horse Diseases / Q000378:metabolism*; D006736:Horses
D001639:Bicarbonates
Renale tubulaire acidose (type 2) bij een friese merrie.