[Activity of coagulation factors II, V, VII and X in healthy dogs--dependence on age, sex and breed].
The activity of the coagulation factors II, V, VII and X was measured in plasmas of 167 healthy dogs of different age, sex and breeds using a test optimized for dogs. During the first months of life particularly the factor X-activity, but also the activity of factor-II-, and by way of suggestion the factor V-activity was lower in comparison to adult dogs. A dependence on the sex was only seen for the factor II- (p = 0.0497) and V-activity (p = 0.0467), which was slightly higher in not castrated female than in male dogs. Significant differences between different breeds existed for factor VII. With regard to a collective of different breeds the reference values (2.5- and 97.5%-quantile) were calculated for adult dogs (n = 111). Especially the range of the factor VII- (62-180%), and also of factor V-activity (68-137%) was wider than that of the factor II- (84-126%) and factor X-activity (77-121%).
Klinik für kleine Haustiere, Tierärztlichen Hochschule Hannover.
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D000375:Aging / Q000097:blood; D000818:Animals; D001947:Breeding; D004285:Dogs / Q000097:blood*; D005165:Factor V / Q000032:analysis*; D005167:Factor VII / Q000032:analysis*; D005170:Factor X / Q000032:analysis*; D005260:Female; D008297:Male; D011516:Prothrombin / Q000032:analysis*; D012016:Reference Values; D012727:Sex Characteristics
D005165:Factor V; D005167:Factor VII; D011516:Prothrombin; D005170:Factor X
Aktivität der Gerinnungsfaktoren II, V, VII und X beim gesunden Hund--Abhängigkeit von Alter, Geschlecht und Rasse.