Successfully treated optic nerve infiltration with adult T-cell lymphoma.
A 45-year-old woman with adult T-cell leukemia had a sudden onset of decreased vision with central scotoma in the right eye. Right optic disc edema and thickening of the optic nerve were observed by magnetic resonance imaging. A diagnosis of leukemic infiltration to the optic nerve was made. A course of oral corticosteroid therapy was prescribed and 40 Gy of radiation was administered to the whole brain and right orbit. Her visual acuity recovered from finger counting to 20/20 within 3 weeks. We believe that this patient represents the first report of successfully treated optic nerve infiltration with adult T-cell leukemia caused by human T-lymphotropic virus type-I infection.
Department of Ophthalmology, Tokyo Medical and Dental University, Japan.
N
N
Yamamoto
M
M
Kiyosawa
T
T
Kawasaki
T
T
Miki
T
T
Fujino
T
T
Tokoro
D005260:Female; D015368:Human T-lymphotropic virus 1; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000628:therapy*; D017254:Leukemic Infiltration / Q000175:diagnosis / Q000628:therapy*; D008875:Middle Aged; D009900:Optic Nerve / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects; D011239:Prednisolone / Q000627:therapeutic use; D011882:Radiotherapy, High-Energy
D011239:Prednisolone