[Specific iatrogenic risks to patients with HIV infection].
Human immunodeficiency virus-infected patients are exposed to more or less specific iatrogenic diseases. The main characteristics of the risks encountered in this field are described: drug intolerance, mostly to sulfamethoxazole-trimethoprim, is extremely frequent; nucleoside analogue antiviral toxicity is reminiscent of that of chemotherapy; nosocomial infections, in general, are more prominent than in HIV-non infected patients. Intravenous line infections are particularly frequent, but these devices are necessary for prolonged intravenous therapies such as anti-CMV treatment of parenteral nutrition. An improved understanding of different etiopathogenic mechanisms and a better approach of the toxicity/efficacy ratio for each treatment would allow to reduce the excessive morbidity due to iatrogenicity.
Service de Médecine Interne, Hôpital Bichat, Paris.
R
R
De Tournemire
P
P
Yeni
D017088:AIDS-Related Opportunistic Infections / Q000209:etiology; D000998:Antiviral Agents / Q000009:adverse effects*; D016516:CD4-CD8 Ratio; D003428:Cross Infection / Q000517:prevention & control; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007049:Iatrogenic Disease; D012307:Risk Factors; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects
D000998:Antiviral Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
Risques iatrogènes particuliers aux patients infectés par le VIH.