[Contrast medium enhanced MR angiography].
Magnetic resonance angiography (MRA) protocols are based on standard sequence protocols like time of flight MRA, which evaluates inflowing spins. This technique is limited by a variety of artifacts like the saturation artifact via turbulent blood flow. Contrast media diminish these artifacts like extracellular agents and blood-pool contrast media. The clinical value of the contrast-enhanced MRA for cerebral pathologies is based on the use of the paramagnetic contrast agent Gd-DTPA. For extracerebral diseases this technique is restricted because of the simultaneous visualization of both arterial and venous vascular territories. Occult venous sinus thrombosis or AV malformations are clinical essential indications for the use of C-MRA. Experimental data prove the excellent contrast abilities of blood-pool agents like Gd-DTPA-polylysin or Gd-DTPA-albumin, which demonstrate long intravascular persistence and retarded excretion.
Strahlenklinik und Poliklinik, Universitätsklinikum Rudolph Virchow, Freien Universität Berlin, Standort Wedding.
T J
TJ
Vogl
Y
Y
Hoffmann
A
A
Mühler
R
R
Felix
D000465:Algorithms; D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D001921:Brain / Q000098:blood supply*; D002533:Cerebral Angiography / Q000379:methods; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008959:Models, Neurological; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D011817:Rabbits
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
Kontrastmittelunterstützte MR-Angiographie.