Synthetic studies of sesquiterpenes with a cis-fused decalin system, 5. A synthetic approach to the study of structure-activity relationships of the termiticidal norsesquiterpenoids, chamaecynone and related compounds.
Various analogues of chamaecynone [1] were prepared from alpha-santonin, and the termiticidal activity of these compounds was examined. All compounds possessing a 5 beta H-13-noreudesmane skeleton with a ethynyl group at C-7 showed significant termiticidal activity. Changes in the structure of the A-ring of these compounds also influenced the potency of their termiticidal activity.
Department of Applied Chemistry, Faculty of Engineering, Niigata University, Japan.
M
M
Ando
K
K
Kikuchi
K
K
Isogai
T
T
Ishiwatari
N
N
Hirata
H
H
Yamazaki
D000818:Animals; D006927:Hymenoptera; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010944:Plants / Q000737:chemistry*; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D013329:Structure-Activity Relationship
D007306:Insecticides; D012717:Sesquiterpenes; C090327:chamaecynone