A sodium magnetic resonance imaging study of acute cerebral ischaemia in the gerbil.
23Na magnetic resonance imaging has been used to investigate sodium changes during and after cerebral ischaemia in a gerbil model. The sodium signal decreased within 4 minutes of the onset of ischaemia, and subsequently increased between 4 and 8 minutes after the onset of reperfusion. These observations may be reflecting the redistribution of tissue sodium resulting from energy failure and recovery.
Department of Neurochemistry, Institute of Neurology, London, U.K.
K L
KL
Allen
A L
AL
Busza
S C
SC
Williams
D000818:Animals; D001812:Blood-Brain Barrier / Q000502:physiology*; D001921:Brain / Q000098:blood supply / Q000473:pathology; D001929:Brain Edema / Q000503:physiopathology*; D002545:Brain Ischemia / Q000503:physiopathology*; D001931:Brain Mapping; D002544:Cerebral Infarction / Q000503:physiopathology; D004734:Energy Metabolism / Q000502:physiology; D005849:Gerbillinae; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D012964:Sodium / Q000378:metabolism*; D014882:Water-Electrolyte Balance / Q000502:physiology*
D012964:Sodium