Comparison of a rice-based, mixed diet versus a lactose-free, soy-protein isolate formula for young children with acute diarrhea.
A randomized clinical trial was completed to compare the efficacy of a mixed diet composed of locally available foods versus a lactose-free, soy-based formula for the management of young Mexican children with acute diarrhea and dehydration. A total of 87 patients between 5 and 36 months of age received either a blended mixed diet containing rice, chicken, carrots, beans, and vegetable oil (group MD) or a soy formula (group SF) immediately after standard oral rehydration therapy. The initial clinical characteristics of the patients in each group were similar, as were their stool outputs during the first 6-hour period of rehydration before the diets were offered. There were six treatment failures, all of which were in group SF (p < 0.01). The stool outputs of children in group MD and in group SF were 82 +/- 55 versus 112 +/- 88 gm/kg per day, respectively, on day 1 (p = 0.037), and 48 +/- 33 versus 66 +/- 55 gm/kg per day on day 2 (p = 0.109). The duration of diarrhea among those in group MD was significantly reduced compared with those in group SF (29 vs 67 hours; p < 0.001). We conclude that the mixed diet resulted in improved clinical outcomes compared with the lactose-free, soy protein isolate formula.
Emergency Department, Instituto Nacional de Pediatria de México, Coyoacan.
I
I
Maulén-Radován
K H
KH
Brown
M A
MA
Acosta
H
H
Fernandez-Varela
D000284:Administration, Oral; D001835:Body Weight; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003967:Diarrhea / Q000178:diet therapy* / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy; D003968:Diarrhea, Infantile / Q000178:diet therapy / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy; D004044:Dietary Proteins / Q000008:administration & dosage*; D005440:Fluid Therapy; D005527:Food, Fortified; D006801:Humans; D007223:Infant; D007225:Infant Food; D008297:Male; D012275:Oryza; D015532:Rehydration Solutions / Q000627:therapeutic use; D012720:Severity of Illness Index; D013025:Glycine max; D013997:Time Factors; D015430:Weight Gain
D004044:Dietary Proteins; D015532:Rehydration Solutions