WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion.
Department of Biochemistry, McGill University, Montreal, Canada.
N
N
Bardeesy
B
B
Zabel
K
K
Schmitt
J
J
Pelletier
D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D003456:Cryptorchidism / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D012734:Disorders of Sex Development / Q000235:genetics; D005260:Female; D016162:Genes, Wilms Tumor; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics; D008297:Male; D008969:Molecular Sequence Data; D009154:Mutation; D009404:Nephrotic Syndrome / Q000235:genetics; D013577:Syndrome; D025721:WT1 Proteins; D009396:Wilms Tumor / Q000235:genetics; D016335:Zinc Fingers
D004268:DNA-Binding Proteins; D025721:WT1 Proteins