[Myelopeptide-1 stimulates humoral immune response in irradiated mice].
Influence of a new bone marrow substance Myelopeptide-1 on the antibody production in the spleen of irradiated mice (2Gy) was studied. Myelopeptide-1 was inoculated in immunized mice at various periods after irradiation by different schemes. It was shown that the stimulating effect of Myelopeptide-1 depended on peptide dose, inoculation scheme, and period between irradiation and immunization.
S Iu
SIu
Shanurin
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000595:Amino Acid Sequence; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology; D001853:Bone Marrow / Q000276:immunology; D001854:Bone Marrow Cells; D005260:Female; D051379:Mice; D008969:Molecular Sequence Data; D009842:Oligopeptides; D010455:Peptides / Q000494:pharmacology*; D011833:Radiation Injuries, Experimental / Q000276:immunology*
D000276:Adjuvants, Immunologic; D009842:Oligopeptides; D010455:Peptides; C048617:myelopeptides
Mielopeptid-1 stimuliruet gumoral'nyĭ immunnyĭ otvet u obluchennykh mysheĭ.