Measurement of the geometric parameters of the aortic bifurcation from magnetic resonance images.
This paper presents a method for measuring arterial geometry in vivo using MRI. The approach was validated using MR images of three perfused compliant casts of human aortic bifurcations whose geometry was known. Preliminary human studies demonstrated the reproducibility of the technique. The approach was applied to 20 normal individuals to study the effects of age, race, and gender on the geometry of the aortic bifurcation. The results show that older people tend to have a smaller bifurcation angle, lower planarity, and larger angular asymmetry than younger people. Asians have larger bifurcation angles than whites. The bifurcation of males is more asymmetric than that of females. These results may have implications regarding the heritability of arterial geometry, the similarities of cardiovascular risk within families, and differences in risk among groups.
Biomedical Engineering Center, Ohio State University, Columbus 43210.
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H
Sun
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BD
Kuban
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Schmalbrock
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MH
Friedman
D000367:Age Factors; D000368:Aged; D000704:Analysis of Variance; D001012:Aorta, Abdominal / Q000033:anatomy & histology*; D044466:Asian People; D002138:Calibration; D003198:Computer Simulation; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D012016:Reference Values; D015203:Reproducibility of Results; D012737:Sex Factors; D044465:White People