The role of n-3 fatty acids in visual and cognitive development: current evidence and methods of assessment.
Low levels of dietary n-3 fatty acids during development lead to changes in the electroretinogram and visual acuity in rats, monkeys, and human infants. Additional aspects of vision can be measured in infants and may provide further useful information about the nature of the changes induced by n-3 fatty acid deficiency and their potential long-term relevance for formula-fed human infants. Several tests are available to assess the development of specific cognitive functions such as visual recognition and short-term memory. These measures can provide information that is not now available to test the hypothesis that n-3 fatty acids are important for other aspects of neural function, including intellectual or cognitive development.
Neuringer
M
M
Department of Medicine, Oregon Health Sciences University, Portland.
Reisbick
S
S
Janowsky
J
J
D000818:Animals; D000831:Animals, Newborn; D002657:Child Development / Q000187:drug effects* / Q000502:physiology; D002675:Child, Preschool; D003071:Cognition / Q000187:drug effects* / Q000502:physiology; D004596:Electroretinography; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology*; D005500:Follow-Up Studies; D000882:Haplorhini; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D007858:Learning / Q000187:drug effects* / Q000502:physiology; D008570:Memory, Short-Term / Q000187:drug effects* / Q000502:physiology; D011597:Psychomotor Performance / Q000187:drug effects; D051381:Rats; D013997:Time Factors; D014787:Vision Tests; D014785:Vision, Ocular / Q000187:drug effects* / Q000502:physiology
D015525:Fatty Acids, Omega-3