Decreased susceptibility to penicillin G and Tet M plasmids in genital and anorectal isolates of Neisseria meningitidis.
Genital and anorectal isolates of Neisseria meningitidis were characterized, and their antimicrobial susceptibilities were determined. Twelve of 43 isolates demonstrated moderate susceptibility to penicillin G (MIC range, 0.125 to 0.5 microgram/ml). Two isolates were resistant to tetracycline (MIC, > or = 8 micrograms/ml) and contained plasmids of 25.2 MDa.
Department of Medicine, University of Washington, Seattle 98195.
K K
KK
Winterscheid
W L
WL
Whittington
M C
MC
Roberts
J R
JR
Schwebke
K K
KK
Holmes
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D005260:Female; D005835:Genitalia / Q000382:microbiology*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009345:Neisseria meningitidis / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D010400:Penicillin G / Q000494:pharmacology*; D010403:Penicillin Resistance / Q000235:genetics; D010957:Plasmids / Q000235:genetics*; D012007:Rectum / Q000382:microbiology*; D013753:Tetracycline Resistance / Q000235:genetics
D000900:Anti-Bacterial Agents; D010400:Penicillin G