Efficacy of fenbendazole against giardiasis in dogs.
Efficacy of fenbendazole at 2 dosages for treating naturally acquired giardiasis in dogs was assessed. Giardia cysts were not detected in the feces of 6 of 6 group-1 dogs (as determined by use of the zinc sulfate concentration technique) after fenbendazole treatment (50 mg/kg of body weight, PO, q 24 h, for 3 doses). Cysts were not detected in the feces of 6 of 6 group-2 dogs after fenbendazole treatment (50 mg/kg of body weight, PO, q 8 h, for 3 days). However, cysts were not detected in the feces of only 1 of 6 group-3 (nontreated control) dogs. Signs of toxicosis were not observed in any dog. These results indicate that the current label dosage (for the treatment of Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Uncinaria stenocephala, Trichuris vulpis, and Taenia pisiformis, but not Giardia spp) of fenbendazole (50 mg/kg, PO, q 24 h, for 3 doses) is also effective for treating giardiasis in dogs.
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
S C
SC
Barr
D D
DD
Bowman
R L
RL
Heller
D000818:Animals; D004283:Dog Diseases; D004285:Dogs; D004334:Drug Administration Schedule; D005273:Fenbendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D005873:Giardiasis / Q000517:prevention & control / Q000662:veterinary*
D005273:Fenbendazole