[HLA and selective IgA deficiency].
A selective deficiency of IgA is developed significantly (p < 0.05) more frequently by HLA-A2-negative than by HLA-A2-positive healthy persons. The frequent combination of A1/A3 is absent. The incidence of HLA-B8-positive persons is increased (p < 0.01). A selective disadvantage is discussed.
Interdisziplinäres HLA-Labor, Medizinische Fakultät, Universität Halle-Wittenberg.
H K
HK
Machulla
G
G
Kunze
A
A
Schaaf
M
M
Hentschel
J
J
Langner
M
M
Seyfarth
D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology*; D006801:Humans; D017098:IgA Deficiency / Q000453:epidemiology / Q000276:immunology*
D006680:HLA Antigens
HLA und selektiver IgA-Mangel.