Cytogenetic analyses of four solid tumours in dogs.
Four solid tumours (one haemangiopericytoma, one haemangioendothelioma, one spindle-cell sarcoma and one mammary carcinoma) in dogs were analysed cytogenetically. In the haemangiopericytoma, an additional small chromosomal segment was present. Very complex changes including centric fusions and symmetric meta-centrics 1, 6, 10 and 12 were conspicuous in the highly unbalanced karyotype of the haemangioendothelioma. Complex changes, particularly many centric fusions and a tandem translocation 4/14, were features of the spindle-cell sarcoma. One centric fusion and a symmetric metacentric 13 were present in the mammary carcinoma.
Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria.
B
B
Mayr
M
M
Reifinger
H
H
Weissenböck
W
W
Schleger
E
E
Eisenmenger
D000231:Adenocarcinoma, Papillary / Q000235:genetics / Q000662:veterinary; D000818:Animals; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D006390:Hemangioendothelioma / Q000235:genetics / Q000662:veterinary; D006393:Hemangiopericytoma / Q000235:genetics / Q000662:veterinary; D007621:Karyotyping / Q000662:veterinary*; D015674:Mammary Neoplasms, Animal / Q000235:genetics; D009369:Neoplasms / Q000235:genetics / Q000662:veterinary*; D012509:Sarcoma / Q000235:genetics / Q000662:veterinary