Familial ovarian cancer.
Two or more epithelial ovarian cancers in close relatives, or ovarian cancer in conjunction with young-onset breast or colonic cancers, are suggestive of an inherited predisposition. Women in such families may have a 30-40% lifetime risk of developing ovarian cancer.
Ngan
H Y
HY
Department of Gynaecology, St Bartholomew's Hospital, London.
Shepherd
J H
JH
D002277:Carcinoma / Q000175:diagnosis / Q000235:genetics* / Q000517:prevention & control; D005260:Female; D006801:Humans; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis / Q000235:genetics* / Q000517:prevention & control; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000517:prevention & control; D010052:Ovariectomy; D012042:Registries