[Prognostic evaluation of patients with arteriosclerosis obliterans].
The natural course of 365 random patients with peripheral arterial obliterative disease was followed up on an average 8 years. In 36% of the patients worsening of angiological condition has been shown. The state of the other patients was unchanged (55%) or improved (9%). During the observation period 87 angiological surgeries and amputation of 41 lower limbs were performed, most of them in 1-2 years after onset of the disease. At follow up in 151 cases myocardial infarction and in 72 cases stroke occurred; the incidence of both diseases was characterized by a cluster like accumulation in 1-3 years before or after onset of the disease. The deterioration of the angiological condition of the patients was related to smoking (mainly heavy smoking), diabetes mellitus and-even more markedly--to the combinations of different risk factors including smoking. The pathological levels of haemorheological factors also showed significant connection with the severity of the disease. In the prospective 6 year period of the study 147 patients (40%) died. This mortality was twice that of the general population matched for age and sex. Information about the cause of death could be collected in 128 cases (87%), among them 51 (40%) died of vascular diseases (peripheral arterial obliterative disease, myocardial infarction, stroke).
Landi
A
A
Fövárosi Szent István Kórház I. Belosztály.
Osgyán
T
T
Gálos
G
G
Keller
L
L
D000368:Aged; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000401:mortality; D001162:Arteriosclerosis Obliterans / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis
Prognosztikai vizsgálatok arteriosclerosis obliteransos betegekben.