[Anti-arrhythmia action of amidinohydrazone substituted benzophenones. 6. Parenteral drug forms of (Z)-2-amino-5-chlorobenzophenone amidinohydrazone acetate (G 256)].
The combination of lyophilized G 256 and a solvent ampoule is recommended as an optimal variant for the application of the compound. In the lyophilized substance both the hydrolysis and the isomerisation are reduced so it is stable enough for the required period of usability.
Fachbereich Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.
M
M
Schleuder
A
A
Keckeis
P H
PH
Richter
T
T
Jira
D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage* / Q000737:chemistry; D001577:Benzophenones / Q000008:administration & dosage* / Q000737:chemistry; D002626:Chemistry, Pharmaceutical; D005612:Freeze Drying; D006835:Hydrazones / Q000008:administration & dosage* / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
D000889:Anti-Arrhythmia Agents; D001577:Benzophenones; D006835:Hydrazones; C080444:(Z)-2-amino-5-chlorobenzophenonamidinohydrazone acetate
Antiarrhythmisch wirksame Amidinohydrazone substituierter Benzophenone. 6. Mitteilung: Parenterale Arzneiformen für des (Z)-2-Amino-5- chlorbenzophenonamidino-hydrazonacetat (G 256).