Effects of matrix metalloproteinases on cartilage biophysical properties in vitro and in vivo.
Bonassar
L J
LJ
Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology, Cambridge 02139.
Paguio
C G
CG
Frank
E H
EH
Jeffries
K A
KA
Moore
V L
VL
Lark
M W
MW
Caldwell
C G
CG
Hagmann
W K
WK
Grodzinsky
A J
AJ
D000818:Animals; D002358:Cartilage, Articular / Q000187:drug effects* / Q000502:physiology; D002417:Cattle; D046508:Culture Techniques; D005260:Female; D006023:Glycoproteins / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D019278:Matrix Metalloproteinase 3; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000494:pharmacology*; D010662:Phenylmercuric Acetate / Q000031:analogs & derivatives / Q000494:pharmacology; D011817:Rabbits; D011994:Recombinant Proteins / Q000494:pharmacology; D013439:Sulfhydryl Reagents / Q000494:pharmacology; D019714:Tissue Inhibitor of Metalloproteinases
D006023:Glycoproteins; D011994:Recombinant Proteins; D013439:Sulfhydryl Reagents; D019714:Tissue Inhibitor of Metalloproteinases; C010024:4-aminophenylmercuriacetate; D008666:Metalloendopeptidases; D019278:Matrix Metalloproteinase 3; D010662:Phenylmercuric Acetate