Two new tryptophan-derived alkaloids from the Okinawan marine sponge Aplysina sp.
Two new indole alkaloids, isoplysin A [2] and D-6-bromohypaphorine [3], have been isolated from the Okinawan marine sponge Aplysina sp. and their structures were elucidated by spectral and chemical means.
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
K
K
Kondo
J
J
Nishi
M
M
Ishibashi
J
J
Kobayashi
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D011161:Porifera / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014364:Tryptophan / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; C090335:isoplysin A; C014372:L-6-bromohypaporphine; D014364:Tryptophan