Cranial nerve conduction and needle electromyography in patients with acoustic neuromas: a model of compression neuropathy.
Of 45 patients with acoustic neuromas (0.3-5.0 cm), 73% had facial nerve impairment on electrophysiologic testing, but only 16% had facial weakness. Cranial nerve conduction was the most sensitive measurement, especially prolongation of the ipsilateral R1 latency of the blink reflex compared with that of the contralateral reflex. The severity of nerve conduction abnormality was highly correlated with tumor size. Our results confirm and quantitate the sensitivity of nerve action potential latency in response to chronic nerve compression.
Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905.
M M
MM
Normand
J R
JR
Daube
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001767:Blinking / Q000502:physiology; D003391:Cranial Nerves / Q000503:physiopathology*; D004576:Electromyography / Q000379:methods; D004594:Electrophysiology / Q000379:methods; D005152:Facial Muscles / Q000294:innervation / Q000503:physiopathology; D005154:Facial Nerve / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality; D005684:Gait; D006311:Hearing Disorders / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009408:Nerve Compression Syndromes / Q000209:etiology / Q000503:physiopathology*; D009431:Neural Conduction; D009464:Neuroma, Acoustic / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D009475:Neurons, Afferent / Q000502:physiology; D012680:Sensitivity and Specificity