Psychophysiological correlates of suicidal behavior in depression. A preliminary study.
P300 and contingent negative variation (CNV) were recorded in depressive inpatients with and without history of suicide attempt. The results show a significant reduction of both P300 and CNV in patients who had attempted suicide as compared with patients who had not. Moreover, a significant correlation was found between the suicidal risk scale and CNV amplitude. Psychophysiological and biochemical implications are discussed.
Hansenne
M
M
Psychiatric Unit, CHU André-Vésale, Montigny-le-Tilleul, Belgium.
Pitchot
W
W
Gonzalez Moreno
A
A
Gonzalez Torrecilas
J
J
Mirel
J
J
Ansseau
M
M
D000328:Adult; D001143:Arousal / Q000502:physiology; D001288:Attention / Q000502:physiology; D002540:Cerebral Cortex / Q000503:physiopathology; D003265:Contingent Negative Variation / Q000502:physiology*; D003866:Depressive Disorder / Q000503:physiopathology* / Q000523:psychology; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010898:Pitch Perception / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013406:Suicide, Attempted / Q000523:psychology*