Increased intracranial pressure and cardiac arrest after heart transplantation. What about the Cushing response in a denervated heart? Case report.
A 13-year-old boy suffered cerebrovascular complications after heart transplantation (ischemic mass effect in the posterior cranial fossa). He had to be resuscitated from cardiac arrest with coma. After a modified cerebellar hemispherectomy the course was favorable.--The most conclusive explanation for the acute event is that a Cushing response was preserved even in the presumably denervated heart.
Department of Neurosurgery, University of Muenster, Westphalia, Fed. Rep. of Germany.
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D
Moskopp
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Kehl
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Horch
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Puskás
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Wassmann
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Schuierer
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Fingerhut
D000293:Adolescent; D002531:Cerebellum / Q000098:blood supply* / Q000473:pathology; D002544:Cerebral Infarction / Q000503:physiopathology* / Q000601:surgery; D003128:Coma / Q000503:physiopathology / Q000601:surgery; D003399:Craniotomy; D004562:Electrocardiography; D004677:Encephalocele / Q000503:physiopathology / Q000601:surgery; D006321:Heart / Q000294:innervation*; D006323:Heart Arrest / Q000503:physiopathology*; D016027:Heart Transplantation / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D007427:Intracranial Pressure / Q000502:physiology*; D008297:Male; D009336:Necrosis; D011183:Postoperative Complications / Q000503:physiopathology / Q000601:surgery; D014057:Tomography, X-Ray Computed