[Quality control of fractionated port scintigraphy in patients with head and neck neoplasms].
The purpose of this study was to evaluate the precision of a technique for shunt measurement and to quantify its relevant influencing factors. Therefore, 10 patients underwent firstly an intraarterial injection of 100 MBq 99mTc-MAA and secondly a fractionated intravenous injection of 4 x 10 MBq 99mTc-MAA. Calculations of the shunt volumina were done with Wheeler's algorithm. In addition the relative shunt volumina for all applications were computed and corrected for (a) tracer retention, (b) biological degradation, (c) physical decay, (d) remaining activities and (e) the combination of (a)-(d). The coefficient of variation was 9.4%. The influence of (a), (b) and (d) was significant and that of (c) not significant. If all influencing factors were ignored (e), no significant differences could be seen, compared to the fully corrected results. Therefore, fractionated shunt scintigraphy is a simple and rapid technique for precisely determining relative shunt volumina in patients under local chemotherapy.
Abt. für Nuklearmedizin und spezielle Biophysik, Medizinische Hochschule Hannover, FRG.
A
A
Kelber
K F
KF
Gratz
A
A
Eckardt
M
M
Lübeck
H
H
Hundeshagen
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D004334:Drug Administration Schedule; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D013438:Sulfhydryl Compounds / Q000008:administration & dosage; D013668:Technetium Tc 99m Aggregated Albumin / Q000008:administration & dosage; D014055:Tomography, Emission-Computed / Q000379:methods*
D013438:Sulfhydryl Compounds; D013668:Technetium Tc 99m Aggregated Albumin; C082426:technetium Tc99m-mercaptoacetyl albumin
Qualitätskontrolle der fraktionierten Port-Szintigraphie bei Patienten mit Kopf-/Hals-Karzinomen.