[Polymeric materials for biomedical purposes obtained by radiation methods. V. hybrid artificial pancreas].
The authors present a review of works done on the elaboration of a hybrid-type artificial pancreas. The article discusses construction designs, applied polymeric materials as well as biocompatibility problems of polymeric membranes that encapsulate the Langerhans islets. On example of hydrogel membranes prepared by radiation crosslinking of poly(vinyl alcohol) (PVA) the dependence of the diffusion coefficients of glucose, insulin and immunoglobulin G on the crosslinking degree of hydrogels has been shown.
Miedzyresortowy Instytut Techniki Radiacyjnej Politechniki Lódzkiej w Lodzi.
K
K
Burczak
J
J
Rosiak
D000818:Animals; D001672:Biocompatible Materials; D003432:Cross-Linking Reagents; D004058:Diffusion; D005947:Glucose / Q000737:chemistry; D006801:Humans; D007074:Immunoglobulin G / Q000737:chemistry; D007328:Insulin / Q000737:chemistry; D007332:Insulin Infusion Systems; D016381:Islets of Langerhans Transplantation; D008567:Membranes, Artificial; D011108:Polymers / Q000528:radiation effects*; D011145:Polyvinyls / Q000528:radiation effects
D001672:Biocompatible Materials; D003432:Cross-Linking Reagents; D007074:Immunoglobulin G; D007328:Insulin; D008567:Membranes, Artificial; D011108:Polymers; D011145:Polyvinyls; D005947:Glucose
Materialy polimerowe do celów biomedycznych otrzymywane metodami radiacyjnymi V. hybrydowa sztuczna trzustka.