Lipoprotein metabolism and atherosclerosis susceptibility in transgenic mice.
Lipoprotein transport genes have been used to make either transgenic or knockout mice with altered lipoprotein levels and metabolism. Either singly or in combination, these mice have provided new animal models of lipoprotein disorders and atherosclerosis.
Breslow
J L
JL
Laboratory of Biochemical Genetics and Metabolism, Rockefeller University, New York.
D000818:Animals; D001053:Apolipoproteins / Q000235:genetics / Q000378:metabolism; D001161:Arteriosclerosis / Q000378:metabolism*; D001692:Biological Transport / Q000502:physiology; D004195:Disease Models, Animal; D004198:Disease Susceptibility / Q000378:metabolism; D015870:Gene Expression; D008074:Lipoproteins / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008822:Mice, Transgenic
D001053:Apolipoproteins; D008074:Lipoproteins