[Current problems in the pathological anatomy of coronary atherosclerosis].
Coronary atherosclerosis is conditioned by structural changes of the arteries that develop starting from the first year of life and manifest in intimal muscular-elastic hyperplasia (IMEH). Lipid accumulation in IMEH may result in the fibrous-lipid plaques development without stage of the lipid spots. IMEH facilitates the development of grave arterial stenosis. Monocytes-macrophages of the subendothelial layer are the source of the foamy cells at the early manifestations of the intimal lipidosis. A characteristic feature of any stage of atherosclerosis is the development of focal necrosis in the altered intima which predetermines membranous calcinosis. Some mechanisms of atherosclerosis reversibility are considered.
Zhdanov
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D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003324:Coronary Artery Disease / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D003327:Coronary Disease / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D003331:Coronary Vessels / Q000378:metabolism / Q000473:pathology; D006801:Humans; D006965:Hyperplasia / Q000378:metabolism / Q000473:pathology; D007223:Infant; D007231:Infant, Newborn; D050356:Lipid Metabolism; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000378:metabolism / Q000473:pathology; D012075:Remission, Spontaneous; D017539:Tunica Intima / Q000378:metabolism / Q000473:pathology
Nekotorye aktual'nye voprosy patologicheskoĭ anatomii koronarnogo ateroskleroza.