Analysis of p53 and ras gene mutations in endometriosis.
No activating mutations in codons 12, 13 and 61 of ras genes nor inactivating mutations in exons 5-9 of the p53 tumor suppressor gene were detected by polymerase chain reaction and single-strand conformation polymorphism methods in either eutopic or ectopic endometrium from 10 women with severe endometriosis.
Clinica Ostetrica e Ginecologica L. Mangiagalli, University of Milan, Italy.
P
P
Vercellini
D
D
Trecca
S
S
Oldani
N S
NS
Fracchiolla
A
A
Neri
P G
PG
Crosignani
D000328:Adult; D004247:DNA / Q000032:analysis; D004715:Endometriosis / Q000235:genetics* / Q000473:pathology; D005091:Exons; D005260:Female; D016158:Genes, p53 / Q000235:genetics*; D006801:Humans; D009154:Mutation; D016133:Polymerase Chain Reaction; D018807:Polymorphism, Single-Stranded Conformational; D018631:ras Proteins / Q000032:analysis* / Q000235:genetics
D004247:DNA; D018631:ras Proteins