Proteus syndrome.
A 10-month-old girl had macrodactyly, facial and extremity hemihypertrophy, plantar cerebriform hyperplasia, a subcutaneous mass on the back, macrocephaly, and lumbar kyphosis. These findings were diagnostic of Proteus syndrome. The clinical features, etiology, management, and points of differential diagnosis are discussed.
Darmstadt
G L
GL
Department of Dermatology, Stanford University School of Medicine, California.
Lane
A T
AT
D003937:Diagnosis, Differential; D005146:Facial Asymmetry / Q000473:pathology; D005260:Female; D005528:Foot / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D006984:Hypertrophy; D007223:Infant; D007738:Kyphosis / Q000473:pathology; D008159:Lumbar Vertebrae / Q000473:pathology; D016715:Proteus Syndrome / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology; D012886:Skull / Q000002:abnormalities