The inhibition of stimulus-secretion coupling in pancreatic islets by volatile anaesthetics does not involve pertussis toxin sensitive G-proteins.
Department of Anaesthesia, St. George's Hospital Medical School, London, U.K.
J P
JP
Desborough
P M
PM
Jones
S J
SJ
Persaud
S L
SL
Howell
D000818:Animals; D002478:Cells, Cultured; D019204:GTP-Binding Proteins / Q000187:drug effects / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism; D007530:Isoflurane / Q000494:pharmacology*; D037342:Pertussis Toxin; D051381:Rats; D010566:Virulence Factors, Bordetella / Q000494:pharmacology
D007328:Insulin; D010566:Virulence Factors, Bordetella; D007530:Isoflurane; D037342:Pertussis Toxin; D019204:GTP-Binding Proteins