Divalent cations elevate cytosolic calcium of chick osteocytes.
Though it is proposed that osteocytes have several functions in bone metabolism, only limited definite information including results of calcium regulation has been forthcoming. We demonstrate here for the first time that the concentration of divalent cations, such as calcium, nickel and cadmium, directly regulates the cytosolic calcium concentration in osteocytes.
Department of Orthodontics, Tokushima University School of Dentistry, Japan.
H
H
Kamioka
K
K
Sumitani
K
K
Tagami
Y
Y
Miki
K
K
Terai
Y
Y
Hakeda
M
M
Kumegawa
T
T
Kawata
D000818:Animals; D002104:Cadmium / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology*; D002478:Cells, Cultured; D002642:Chick Embryo; D003600:Cytosol / Q000378:metabolism*; D009532:Nickel / Q000494:pharmacology*; D010011:Osteocytes / Q000187:drug effects* / Q000378:metabolism
D002104:Cadmium; D009532:Nickel; D002118:Calcium