Basal ganglia calcifications and ALS syndrome.
We report the case of a patient with idiopathic hypoparathyroidism and unusually large symmetrical calcifications in the basal ganglia, thalami, cerebellar hemispheres and brainstem, who clinically presented an ALS-like syndrome. We discuss the possible role of abnormal calcium metabolism in the pathogenesis of motoneuron disease.
Clinica Neurologica, Università di Palermo.
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Scarpitta
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Pisciotta
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Fierro
D000690:Amyotrophic Lateral Sclerosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D001479:Basal Ganglia / Q000000981:diagnostic imaging / Q000473:pathology*; D001933:Brain Stem / Q000000981:diagnostic imaging / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology*; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007011:Hypoparathyroidism / Q000150:complications / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013577:Syndrome; D013788:Thalamus / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed