Mapping of the breast basic conserved gene (D16S444E) to human chromosome band 16q24.3.
The breast basic conserved gene (D16S444E) is a candidate tumor suppressor gene previously mapped to human chromosome 16. We determined the map position of D16S444E more precisely using a somatic mouse x human hybrid panel and fluorescence in situ hybridization on metaphase spreads and interphase nuclei. We show that the D16S444E gene is localized on band 16q24.3 and is located between APRT and D16S44.
Department of Pathology, University of Leiden, The Netherlands.
A M
AM
Cleton-Jansen
H W
HW
Moerland
D F
DF
Callen
N A
NA
Doggett
P
P
Devilee
C J
CJ
Cornelisse
D000818:Animals; D001483:Base Sequence; D002842:Chromatids; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D017931:DNA Primers; D016147:Genes, Tumor Suppressor; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D051379:Mice; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods
D017931:DNA Primers