[Critical myocardial ischemia in systemic lupus erythematosus. Case report].
We present the clinical case of a 26-year-old woman, suffering systemic lupus erythematosus for 15 years, who suddenly had coronary heart disease with angina pectoris on mild effort. Thallium 201 exercise test demonstrated clearcut anteroseptal and apical perfusion defects, whereas repeated echocardiography showed a hypokinetic anteroseptal segment; ECG also reported new Q wave in lead V4. After stronger corticosteroid and immunosuppressive treatment, angina pectoris attenuated and perfusion defects disappeared within few months. We hypothesize a coronary artery vasculitis in the course of systemic lupus erythematosus, probably associated with early coronary artery atherosclerosis.
Astorri
E
E
Cattedra di Cardiologia, Università degli Studi di Parma.
Ridolo
E
E
Dall'Aglio
P P
PP
Gavaruzzi
G
G
Contini
G A
GA
Albertini
D
D
D000328:Adult; D000787:Angina Pectoris / Q000175:diagnosis / Q000209:etiology; D003327:Coronary Disease / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D004452:Echocardiography; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D011877:Radionuclide Imaging
Ischemia miocardica critica in corso di lupus eritematoso sistemico. Descrizione di un caso clinico.