Localization of the human coproporphyrinogen oxidase gene to chromosome band 3q12.
The human gene encoding coproporphyrinogen oxidase is the defective gene in hereditary coproporphyria. This gene was mapped to chromosome band 3q12 using fluorescent in situ hybridization. The chromosomal localization was confirmed by cosegregation of the human gene with chromosome 3 in a panel of human/rodent somatic hybrids.
Laboratoire de Biologie du Développement, Hôpital Robert Debré, Paris, France.
V
V
Cacheux
P
P
Martasek
F
F
Fougerousse
M H
MH
Delfau
L
L
Druart
G
G
Tachdjian
B
B
Grandchamp
D000818:Animals; D001483:Base Sequence; D002478:Cells, Cultured; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D003304:Coproporphyrinogen Oxidase / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D008214:Lymphocytes; D008969:Molecular Sequence Data; D012377:Rodentia
D003304:Coproporphyrinogen Oxidase