Effect of trace metals on production of exoprotein and beta-lactamase by Staphylococcus aureus.
A minimum concentration of 0.01 mM of Mg2+ was essential for any growth of S. aureus. Of the trace metals, Mg2+ and Ca2+ were highly stimulatory for growth. All trace metals except Ni2+ in small concentrations were stimulatory for growth and exoprotein production. Amounts of exoprotein and beta-lactamase produced relative to the number of viable cells were maximum during the period of suboptimal proliferation of bacteria. Trace metals did not significantly influence the amount of beta-lactamase produced relative to exoprotein.
Bhat
K G
KG
Department of Microbiology, Kasturba Medical College, Mangalore, India.
Hegde
B K
BK
Shivananda
P G
PG
D001426:Bacterial Proteins / Q000096:biosynthesis*; D005069:Evaluation Studies as Topic; D008670:Metals / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000378:metabolism; D001618:beta-Lactamases / Q000096:biosynthesis*
D001426:Bacterial Proteins; D008670:Metals; D001618:beta-Lactamases