[Malignant epidermoid tumors of the anus. Etiopathogenesis and clinical aspects].
Malignant squamous tumors of the anus (MSTA) are most often carcinomas of the anus (80 to 85%) but remain rare. They occur above all in women between the age of 45 and 70. Three groups are considered to be high-risk: passive homosexuals, individuals with anal condylomas (in particular HIV+) and women with genital dysplasias or carcinomas. The presentation of MSTA is variable and often quite non-specific: bleeding, pain, pruritus, discharge. Proctological examination reveals an ulcerated lesion, proliferative or infiltrating. The diagnosis is confirmed by biopsy. Clinical (often under general anesthesia) and paraclinical (endoscopy, CT scan and endo-anal ultrasonography) evaluation is necessary. This involves three levels: local (enabling determination of spread in terms of height and circumference and/or infiltration of deep layers), regional (detection of inguinal and/or pelvirectal lymphadenopathy) and general (detection of bone, liver or lung metastases). This evaluation enables classification of the tumor, forming the basis of management choices and defining its prognosis.
Service de Gastroentérologie, CHU Rangueil, Toulouse.
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Suduca
D000368:Aged; D001005:Anus Neoplasms / Q000209:etiology* / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology*; D005260:Female; D015658:HIV Infections; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012307:Risk Factors
Tumeurs épidermoïdes malignes de l'anus. Etiopathogénie et clinique.