[A comparative evaluation of the hypoglycemic activity of acetyl-alpha-carnitine and chlorpropamide in experimental diabetes].
The comparison of the action shown by acetyl-alpha-carnitine and chloropropamide in rabbits with experimental diabetes has demonstrated that the former has a more pronounced hypoglycemic action. In combined administration, acetyl-alpha-carnitine substantially enhanced the effects of chloropropamide in the animals with experimental diabetes, which should be taken into account by clinicians in its use.
Kim
E K
EK
Trevisani
K
K
Trevisani
M
M
Suslina
Z A
ZA
Seĭfulla
R D
RD
D000108:Acetylcarnitine / Q000627:therapeutic use*; D000818:Animals; D001786:Blood Glucose / Q000032:analysis / Q000187:drug effects; D002747:Chlorpropamide / Q000627:therapeutic use*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D011817:Rabbits; D013997:Time Factors
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D000108:Acetylcarnitine; D002747:Chlorpropamide
Sravnitel'naia ostenka gipoglikemicheskoĭ aktivnosti atsetil-al'fa-karnitina i khlorpropamida pri éksperimental'nom diabete.