[Low molecular weight heparin (parnaparin) versus calcium heparin in the prevention of thromboembolic disease in general surgery].
In general surgery the incidence of deep vein thrombosis is between 10 and 40% according to age, the length and type of operation and the pathology "risk" associated. Prevention is undoubtedly the best way to avoid this complication. The aim of this study was to confirm, in 160 patients split in two groups, the clinical effectiveness and the usefulness of a low molecular weight heparin (parnaparin) versus calcium heparin. Both drugs demonstrated high effectiveness in prevention of deep vein thrombosis and or pulmonary embolism. In our opinion, however, parnaparin has a more protective and a less hemorrhagic inter-operation effect than calcium heparin and, not last, the advantage of a single daily administration.
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Istituto di Chirurgia Generale e Neurochirurgia, Università degli Studi di Palermo.
Arcara
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Scaffidi Abbate
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Mercadante
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006493:Heparin / Q000627:therapeutic use*; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000517:prevention & control*; D013923:Thromboembolism / Q000517:prevention & control*
D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; C006871:calcium heparin; D006493:Heparin; C080945:parnaparin
Una eparina a basso peso molecolare (parnaparin) versus eparina calcica. Nella profilassi della malattia trombo-embolica in chirurgia generale.