Molecular computation of solutions to combinatorial problems.
The tools of molecular biology were used to solve an instance of the directed Hamiltonian path problem. A small graph was encoded in molecules of DNA, and the "operations" of the computation were performed with standard protocols and enzymes. This experiment demonstrates the feasibility of carrying out computations at the molecular level.
Department of Computer Science, University of Southern California, Los Angeles 90089.
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Adleman
D000465:Algorithms; D001483:Base Sequence; D004247:DNA / Q000737:chemistry; D008432:Mathematical Computing; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D016133:Polymerase Chain Reaction
D009838:Oligodeoxyribonucleotides; D004247:DNA