[Increased wound healing disorders in patients with inguinal hernia caused by administration of antithrombotic agents in the abdominal wall].
In a prospective, randomized study, including 108 patients, we investigated the effect of different locations for the subcutaneous injection of low dosed or low molecular heparin following standard herniotomia. In the group with injection into the contralateral abdominal wall the rate of local surgical complications was four times higher compared to those patients with injections into the thigh. Thus we conclude that after herniotomia low dosed or low molecular heparin should be applied into the subcutis of the thigh.
Chirurgische Klinik, Städtischen Kliniken Dortmund.
H
H
Lemke
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M
Imhoff
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D
Löhlein
D000328:Adult; D004087:Dihydroergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D006406:Hematoma / Q000139:chemically induced; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000009:adverse effects*; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D011183:Postoperative Complications / Q000139:chemically induced / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000139:chemically induced; D013923:Thromboembolism / Q000517:prevention & control*; D014945:Wound Healing / Q000187:drug effects*
D004338:Drug Combinations; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; C031388:heparin-dihydergot; C006871:calcium heparin; D004087:Dihydroergotamine; D006493:Heparin
Vermehrte Wundheilungsstörungen bei Leistenhernienpatienten durch Applikation der Thromboseprophylaxe in die Bauchdecken.