[Visceral leishmaniasis with gastrointestinal involvement in a 30-year-old HIV infected patient].
We report the case of a 30-years old HIV-infected woman who suffered from recurrent fever up to 41 degrees C, loss of appetite, loss of 8 kg body weight and swelling of the cervical and inguinal lymph nodes. The diagnostic work-up revealed infection with leishmania in gastric and duodenal biopsies. The parasites were also found in the inguinal lymph nodes and in the bone marrow of the patient. According to patient's history the infection was acquired on a holiday in southern spain. The patient was treated with pentavalent antimony in combination with interferon gamma. Visceral leishmaniosis in immuno-suppressed patients is discussed and therapeutic approaches are described.
Medizinische Klinik und Poliklinik, Heinrich-Heine-Universität Düsseldorf.
H
H
Jablonowski
H
H
Szelényi
F
F
Borchard
E
E
Döhring-Schwerdtfeger
K J
KJ
Hengels
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D000328:Adult; D000967:Antimony Sodium Gluconate / Q000627:therapeutic use; D001706:Biopsy; D003131:Combined Modality Therapy; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use; D007411:Intestinal Diseases, Parasitic / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D007413:Intestinal Mucosa / Q000473:pathology; D007898:Leishmaniasis, Visceral / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D007371:Interferon-gamma; D000967:Antimony Sodium Gluconate
Viszerale Leishmaniose mit gastrointestinalem Befall bei einer 30-jährigen HIV-infizierten Patientin.