Synthesis and action on the central nervous system of 9,10-dihydropyrrolo [3,4-b][1,4]benzoxazepine derivatives.
The synthesis of tricyclic system ring, 9,10-dihydropyrrolo[3,4-b] [1,4]benzoxazepine, and its derivatives is described. Some of the chemical and pharmacological properties of these compounds are also reported.
Institute of Chemistry, School of Medicine, Lódź, Poland.
E
E
Budzisz
K
K
Kostka
A
A
Szadowska
W
W
Pakulska
D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001831:Body Temperature / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects*; D005260:Female; D006993:Hypnotics and Sedatives / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D010077:Oxazepines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
D000927:Anticonvulsants; D006993:Hypnotics and Sedatives; D010077:Oxazepines