Update: trends in AIDS diagnosis and reporting under the expanded surveillance definition for adolescents and adults--United States, 1993.
The expansion of the surveillance case definition for acquired immunodeficiency syndrome (AIDS) in January 1993 (1) resulted in a large increase in reported AIDS cases. This increase has primarily reflected reports of human immunodeficiency virus (HIV)-infected persons in whom severe immunosuppression (CD4+ count < 200 T-lymphocytes/microL or a CD4+ T-lymphocyte percentage of total lymphocytes of < 14) had been diagnosed, which typically occurs before the onset of AIDS-defining opportunistic illnesses (AIDS-Ols, CDC clinical category C disease) (1,2). The inclusion of the CD4+ reporting criteria in AIDS surveillance has required an alteration in methods used to assess trends in AIDS incidence, previously based on the diagnosis of AIDS-Ols. This report first summarizes information about AIDS cases reported during 1993; then, to describe trends in AIDS incidence if the surveillance definition had not been expanded, this report uses estimates of eventual AIDS-Ol diagnosis dates for persons who were reported with AIDS based only on the CD4+ criteria.
D015492:AIDS Serodiagnosis / Q000706:statistics & numerical data* / Q000639:trends; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D018791:CD4 Lymphocyte Count; D018563:Disease Notification / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D014481:United States / Q000453:epidemiology