Fine-needle aspiration biopsy of pituitary carcinoma with cervical lymph node metastases: a report of two cases and review of the literature.
Metastases from pituitary carcinomas are rare lesions that can mimic other tumors on fine-needle aspiration biopsies. Two patients with primary pituitary neoplasms developed cervical lymph node metastases, which were sampled and diagnosed correctly using the fine-needle aspiration biopsy technique. These two cases demonstrate the varied cytologic patterns of pituitary neoplasms, ranging from uniform bland cells to cells with striking anaplastic features. The time period between the onset of symptoms and subsequent metastases is unpredictable as well, underscoring the need for an accurate clinical history before a meaningful cytologic interpretation is made.
Department of Pathology, School of Medicine, University of California, San Francisco.
D M
DM
Cartwright
T R
TR
Miller
A J
AJ
Nasr
D000328:Adult; D001707:Biopsy, Needle / Q000379:methods; D002277:Carcinoma / Q000556:secondary*; D005260:Female; D006258:Head and Neck Neoplasms / Q000556:secondary; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000473:pathology*