Mapping the human pulmonary surfactant-associated protein B gene (SFTP3) to chromosome 2p12-->p11.2.
Pulmonary surfactant, a lipoprotein complex is essential for normal lung function. The non-serum surfactant-associated proteins, SP-A, SP-B, and SP-C, play important roles in the biology of pulmonary surfactant. We have mapped the human SP-B gene (SFTP3) to chromosome 2, band 2p12-->p11.2 by fluorescent in situ hybridization.
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD.
N C
NC
Vamvakopoulos
W S
WS
Modi
J
J
Floros
D001483:Base Sequence; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D017931:DNA Primers; D015342:DNA Probes; D006023:Glycoproteins / Q000235:genetics; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008677:Metaphase; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011510:Proteolipids / Q000235:genetics*; D011663:Pulmonary Surfactants / Q000235:genetics*; D015183:Restriction Mapping
D017931:DNA Primers; D015342:DNA Probes; D006023:Glycoproteins; D011510:Proteolipids; D011663:Pulmonary Surfactants