Immunoglobulin deficiency and recurrent postmenopausal endometritis.
Secretory immunoglobulin A is the principal immunoglobulin of mucosal surfaces and may be reduced in postmenopausal women because of estrogen deficiency. This can manifest as recurrent infections and may be a cause of undiagnosed postmenopausal bleeding. Regular serum immunoglobulin therapy is appropriate for these patients.
Barrington
J W
JW
Department of Obstetrics and Gynaecology, Llandough Hospital, Penarth, South Glamorgan, United Kingdom.
Papagiannis
A
A
Roberts
A
A
D000361:Agammaglobulinemia / Q000150:complications* / Q000188:drug therapy; D004716:Endometritis / Q000209:etiology*; D005260:Female; D006801:Humans; D007071:Immunoglobulin A, Secretory; D007136:Immunoglobulins / Q000627:therapeutic use; D008875:Middle Aged; D017698:Postmenopause; D012008:Recurrence; D014592:Uterine Hemorrhage / Q000209:etiology
D007071:Immunoglobulin A, Secretory; D007136:Immunoglobulins