Differentiation of follicular adenoma and carcinoma of thyroid by immunohistochemical demonstration of ceruloplasmin.
In this study, and attempt was made to differentiate between follicular neoplasms of the thyroid using an immunoperoxidase staining technique for detection of ceruloplasmin. 54 histologically proved benign and malignant thyroidal lesions were selected. The staining for ceruloplasmin was consistently positive in follicular carcinoma and negative in follicular adenoma.
Department of Pathology, Seth G.S. Medical College, Parel, Bombay.
P
P
Vaideeswar
A A
AA
Pandit
P H
PH
Khilnani
H S
HS
Powar
D000236:Adenoma / Q000737:chemistry* / Q000175:diagnosis*; D014408:Biomarkers, Tumor / Q000032:analysis; D002570:Ceruloplasmin / Q000032:analysis*; D006801:Humans; D013964:Thyroid Neoplasms / Q000737:chemistry* / Q000175:diagnosis*
D014408:Biomarkers, Tumor; D002570:Ceruloplasmin