[Thyrotoxic crisis after exposure to iodine. A case with fatal outcome].
A 78-year-old woman is presented with a multinodular toxic goiter and euthyroidism under continuous low-dose treatment with antithyroid drugs. A period of hyperthyroidism had been documented 3 years previously. In the preoperative management, prior to resection of a benign ovarian tumour, an intravenous urogram was performed. Perchlorate was given for thyroid protection. One day after surgery the clinical signs of thyroid storm were observed. Immediately, high-dose antithyroid drug therapy was started. Nevertheless, the patient died of acute cardiovascular failure 3 days later. This case report focuses on the risk of thyroid storm following iodine excess in the presence of relevant functional thyroid autonomy without adequate thyroid protection.
Abteilung Nuklearmedizin, Radiologische Universitätsklinik Freiburg.
H
H
Blattmann
M
M
Reinhardt
C
C
Schümichen
E
E
Moser
D000368:Aged; D003537:Cystadenoma / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D006044:Goiter, Nodular / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007044:Hysterectomy; D007455:Iodine / Q000009:adverse effects*; D008713:Methimazole / Q000008:administration & dosage*; D010051:Ovarian Neoplasms / Q000601:surgery*; D010472:Perchlorates / Q000008:administration & dosage; D011183:Postoperative Complications / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D017670:Sodium Compounds / Q000008:administration & dosage; D013958:Thyroid Crisis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D013960:Thyroid Function Tests; D014567:Urography
D010472:Perchlorates; D017670:Sodium Compounds; D008713:Methimazole; D007455:Iodine; C031068:sodium perchlorate
Thyreotoxische Krise nach Jodexposition. Ein Fall mit letalem Ausgang.