[Isolated and combined effects of low-level ionizing radiation and hydroquinone on the humoral immunity in the regional lymph nodes].
The whole-body exposure of mice to 0.1 Gy gamma-radiation resulted in stimulation of T-cell dependent humoral immune response in lymph nodes. At the same time enhancement of susceptibility of immunocompetent cells to damaging effect of hydroquinone was observed. Under irradiation with doses of 0.5 or 1 Gy which cause dose-dependent immunosuppression, hydroquinone induced stimulation of antigen production.
A N
AN
Sharetskiĭ
B P
BP
Surinov
M R
MR
Abramova
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects / Q000528:radiation effects*; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D004912:Erythrocytes / Q000276:immunology; D006873:Hydroquinones / Q000494:pharmacology*; D007114:Immunization; D008198:Lymph Nodes / Q000187:drug effects / Q000276:immunology* / Q000528:radiation effects; D051379:Mice; D011829:Radiation Dosage; D011837:Radiation-Protective Agents / Q000494:pharmacology*
D006873:Hydroquinones; D011837:Radiation-Protective Agents; C031927:hydroquinone
Izolirovannoe i sochetannoe vozdeĭstvie ioniziruiushcheĭ radiatsii v nizkikh dozakh i gidrokhinona na gumoral'nyĭ otvet v regionarnykh limfaticheskikh uzlakh.