Management of recurrent priapism with epinephrine self-injection and gonadotropin-releasing hormone analogue.
A case of recurrent priapism in a young black man without sickle cell anemia is reported. Due to almost daily episodes of prolonged painful erections, the patient was instructed in intracorporeal injection using an epinephrine self-injection kit, which provided complete detumescence on 31 occasions. The patient refused surgical intervention and was treated with monthly intra-muscular gonadotropin-releasing hormone analogue. Priapism episodes completely abated by the second and final monthly gonadotropin-releasing hormone analogue injection without recurrence during 4 months of followup. Normal erectile function was maintained during and after gonadotropin-releasing hormone analogue therapy. Epinephrine self-injection and gonadotropin-releasing priapism.
Division of Urology, Deaconess Hospital, Boston, Massachusetts.
J
J
Steinberg
R C
RC
Eyre
D000328:Adult; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000008:administration & dosage*; D006801:Humans; D007273:Injections, Intramuscular; D016729:Leuprolide / Q000008:administration & dosage*; D008297:Male; D011317:Priapism / Q000188:drug therapy*; D012008:Recurrence; D012646:Self Administration
D016729:Leuprolide; D004837:Epinephrine