[Cytochemical examination of peripheral blood neutrophils of patients with hypothyroidism].
In patients with primary hypothyroidism a decrease of activity of acid phosphatase and beta-glucuronidase and an increase of arylsulphatase activity were found in cytochemical investigations of peripheral blood neutrophils. In the group of patients a decrease was also observed of the value of indices of spontaneous and stimulated nitroblue tetrazolium reduction. In patients with primary hypothyroidism a number of abnormalities may develop manifesting themselves as changed outfit of the neutrophils with lysosomal enzymes, and weakening may occur in these cells of redox processes evaluated by the test with nitroblue tetrazolium. The presence of the above mentioned features in the neutrophils may be interpreted as a part of metabolic and functional disturbances in the tissues of various organs in patients with hypothyroidism.
Hrycek
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II Katedry i Kliniki Chorób Wewnetrznych Sl. Ak. Med. w Katowicach.
D000135:Acid Phosphatase / Q000097:blood; D000328:Adult; D000368:Aged; D001192:Arylsulfatases / Q000097:blood; D005260:Female; D005966:Glucuronidase / Q000097:blood; D006651:Histocytochemistry; D006801:Humans; D007037:Hypothyroidism / Q000097:blood*; D008875:Middle Aged; D009504:Neutrophils / Q000201:enzymology*; D009580:Nitroblue Tetrazolium
D009580:Nitroblue Tetrazolium; D000135:Acid Phosphatase; D001192:Arylsulfatases; D005966:Glucuronidase
Badania cytochemiczne granulocytów obojetnochłonnych krwi obwodowej u chorych z niedoczynnościa tarczycy.