Percutaneous absorption and inflammation in aged skin: a review.
We review experimental studies that address age-related changes in cutaneous barrier function and dermal blood vessel function. These differences have important implications in the understanding of age-related changes in the inflammatory process and topical drug delivery systems.
Harvell
J D
JD
Department of Dermatology, School of Medicine, University of California at San Francisco.
Maibach
H I
HI
D000368:Aged; D003877:Dermatitis, Contact / Q000209:etiology / Q000503:physiopathology*; D017453:Dermatitis, Irritant / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D012867:Skin / Q000098:blood supply*; D012869:Skin Absorption / Q000502:physiology*; D015595:Skin Aging / Q000502:physiology*