Approach to the patient with abnormal liver enzymes.
Elevated serum enzyme values are often the earliest indicators of liver injury in asymptomatic patients. Abnormal AST and ALT point to a hepatocyte disorder; abnormal alkaline phosphatase suggests a biliary tract disorder. Selected case histories illustrate how the three enzyme levels, in conjunction with the history and physical examination, can guide the rest of the workup.
Johns Hopkins University School of Medicine, Baltimore.
H F
HF
Herlong
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood*; D000469:Alkaline Phosphatase / Q000097:blood*; D001219:Aspartate Aminotransferases / Q000097:blood*; D001327:Autoimmune Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006525:Hepatitis, Viral, Human / Q000175:diagnosis; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase