Chromosome aberrations in fibrous dysplasia.
We report the cytogenetic findings of two cases of fibrous dysplasia, one occurring in the tibia, the other in the sphenoid. Both cases exhibited only one chromosome change: a t(6;11)(q15;p15) in the first case, a derivative chromosome 2 in the second. The previous cytogenetic report on fibrous dysplasia revealed only numerical changes. The significance of these inconsistent chromosomal findings in fibrous dysplasia is unclear.
Dal Cin
P
P
Center for Human Genetics, University of Leuven, Belgium.
Sciot
R
R
Speleman
F
F
Samson
I
I
Laureys
G
G
de Potter
C
C
Meire
F
F
van Damme
B
B
van den Berghe
H
H
D000328:Adult; D002648:Child; D002869:Chromosome Aberrations; D002880:Chromosomes, Human, Pair 11; D002889:Chromosomes, Human, Pair 2; D002896:Chromosomes, Human, Pair 6; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping