Unexplained CD4+ T-lymphocytopenia without evidence of HIV infection.
The human immunodeficiency virus, HIV has long been known to be associated with CD4+ T-lymphocytopenia. In clinical practice, a low CD4 count usually implies an underlying HIV infection until proven otherwise. Non-HIV related CD4 depletion is a rare phenomenon, but has caused much public concern. A Chinese lady with unexplained CD4+ T-lymphocytopenia is presented, followed by a review of the condition as well as its practical implications.
Department of Health, Queen Elizabeth Hospital, Hong Kong.
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Lee
D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes; D003937:Diagnosis, Differential; D005260:Female; D015658:HIV Infections / Q000175:diagnosis; D006801:Humans; D007970:Leukopenia / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged