Inability of (-)deprenyl to modify copulatory performance in the male rat, whether or not stimulated by the selective D2 dopamine agonist SND 919.
Intraperitoneal injection of the selective D2 dopamine agonist SND 919 (0.1 and 1 mg kg-1) significantly accelerated the copulatory behaviour of sexually-active rats, diminishing the number of mounts, intromissions and latency to ejaculation. Subchronic (-)deprenyl did not produce any significant effect on the copulatory behaviour of sexually-active and -inactive male rats or modify the sexual stimulation exerted on the same sexually-active rats by SND 919, when acutely injected at 1 mg kg-1.
Department of Biomedical Sciences, University of Modena, Italy.
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F
Ferrari
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Giuliani
D000818:Animals; D052160:Benzothiazoles; D003307:Copulation / Q000187:drug effects*; D018491:Dopamine Agonists / Q000494:pharmacology*; D008297:Male; D000077487:Pramipexole; D051381:Rats; D017208:Rats, Wistar; D017448:Receptors, Dopamine D2 / Q000819:agonists*; D012642:Selegiline / Q000494:pharmacology*; D013844:Thiazoles / Q000494:pharmacology*
D052160:Benzothiazoles; D018491:Dopamine Agonists; D017448:Receptors, Dopamine D2; D013844:Thiazoles; D012642:Selegiline; D000077487:Pramipexole