Localization of human ARF2 and NCK genes and 13 other NotI-linking clones to chromosome 3 by fluorescence in situ hybridization.
Two human genes containing NotI sites, ADP-ribosylation factor (ARF2) and melanoma NCK protein, were mapped by fluorescence in situ hybridization to 3p21.2-->p21.1 and 3q21, respectively. Thirteen other NotI-linking clones, representing sequence tagged sites, were also mapped to different regions of human chromosome 3. Two of these clones that contain sequences 80% homologous to the rat tropoelastin gene and brain Cl- channel protein CLC-2 gene probably represent new human genes closely related to the known rat genes.
Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk.
N
N
Vorobieva
A
A
Protopopov
M
M
Protopopova
V
V
Kashuba
R L
RL
Allikmets
W
W
Modi
E R
ER
Zabarovsky
G
G
Klein
L
L
Kisselev
A
A
Graphodatsky
D020727:ADP-Ribosylation Factors; D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002352:Carrier Proteins / Q000235:genetics; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D015252:Deoxyribonucleases, Type II Site-Specific; D019204:GTP-Binding Proteins / Q000235:genetics*; D008040:Genetic Linkage; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods; D008545:Melanoma / Q000235:genetics; D008969:Molecular Sequence Data; D015513:Oncogene Proteins / Q000235:genetics*; D051381:Rats; D015183:Restriction Mapping
D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; C078332:Nck protein; D015513:Oncogene Proteins; D015252:Deoxyribonucleases, Type II Site-Specific; C038565:GCGGCCGC-specific type II deoxyribonucleases; D019204:GTP-Binding Proteins; C486434:Arf2 protein, rat; D020727:ADP-Ribosylation Factors; C116688:ARF4 protein, human