Autoimmune haemolytic anaemia during pregnancy.
We describe a 31-year-old woman, who presented during her first pregnancy, with severe haemolytic anaemia due to auto-immune antibodies against erythrocytes. IgG warm-antibodies, as well as IgM antibodies were found in her serum. This idiopathic form of auto-immune haemolysis was successfully treated with glucocorticoids. During her second pregnancy auto-immune haemolysis again developed and was treated similarly. Two healthy children were born. The uneventful outcome we saw with our patient is in keeping with other reports in the literature.
Department of Internal Medicine, st. Maartens Gasthuis, Venlo, The Netherlands.
C E
CE
Benraad
H A
HA
Scheerder
M A
MA
Overbeeke
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007231:Infant, Newborn; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D017701:Reticulocyte Count
D006454:Hemoglobins; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007770:L-Lactate Dehydrogenase; D011241:Prednisone