Human TIMP-1 binds to pro-M(r) 92K GL (gelatinase B, MMP-9) through the "second disulfide knot".
Bodden
M K
MK
Department of Oral Biology, University of Alabama School of Dentistry, Birmingham 35294.
Windsor
L J
LJ
Caterina
N C
NC
Harber
G J
GJ
Birkedal-Hansen
B
B
Birkedal-Hansen
H
H
D000595:Amino Acid Sequence; D001665:Binding Sites; D001667:Binding, Competitive; D017364:Collagenases / Q000737:chemistry* / Q000378:metabolism*; D004220:Disulfides; D006023:Glycoproteins / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D020780:Matrix Metalloproteinase 9; D061965:Matrix Metalloproteinase Inhibitors; D008961:Models, Structural; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009842:Oligopeptides / Q000494:pharmacology; D017433:Protein Structure, Secondary; D019714:Tissue Inhibitor of Metalloproteinases
D004220:Disulfides; D006023:Glycoproteins; D061965:Matrix Metalloproteinase Inhibitors; D009842:Oligopeptides; D019714:Tissue Inhibitor of Metalloproteinases; D017364:Collagenases; D020780:Matrix Metalloproteinase 9