[The efficacy of verapamil in sustained monomorphic ventricular tachycardia].
We present a 36-year-old male without overt cardiac disease who suffered, since he was 15 years old, from sustained monomorphic ventricular tachycardia of left bundle branch block with a right axis, lasting for several hours; sometimes, syncope was a clinical form of manifestation. Electrophysiologic study, twenty-four hours Holter recording, cardiac catheterization and blood analysis were not useful in order to find its etiology. Efficacy of different drugs, like Mexiletil, Amiodarone, Atenolol and Verapamil (at a dose of 240 mg/day) were tested through multistaged graded-treadmill stress-testing using the Bruce protocol. Ventricular tachycardia was suppressed by administration of Lidocaine. Oral verapamil given at a dose of 360 mg/day prevented the induction of the arrhythmia, the efficacy was tested with maximal treadmill exercise and twenty-four hours Holter recording.
Servicio de Cardiología, Hospital de Cruces, Baracaldo, Vizcaya.
J R
JR
Rumoroso
A
A
Bodegas
J
J
Subinas
P M
PM
Montes
R
R
Sanz
D
D
Rodrigo
J I
JI
Barrenetxea
D000328:Adult; D002304:Cardiac Pacing, Artificial; D002908:Chronic Disease; D004341:Drug Evaluation; D015716:Electrocardiography, Ambulatory / Q000187:drug effects; D005080:Exercise Test / Q000187:drug effects; D006801:Humans; D008297:Male; D017180:Tachycardia, Ventricular / Q000175:diagnosis / Q000188:drug therapy*; D014700:Verapamil / Q000627:therapeutic use*
D014700:Verapamil
Eficacia del verapamilo en la taquicardia ventricular monomorfa sostenida.