A heterochromatic P sequence in the D. subobscura genome.
The study of a heterochromatic P sequence of D. subobscura reveals that it is a degraded element, located at the centromeric region of the A chromosome (X chromosome in this species), and that it is strongly diverged from the euchromatic P sequences previously described in this species. This heterochromatic sequence is composed of some P element fragments embedded in undefined beta-heterochromatic sequences. These mosaic P sequences do not show any transcriptional activity and seem to be ancient parasites of the D. subobscura genome. Phylogenetic analyses indicate that both the euchromatic and heterochromatic P sequences of D. subobscura could come from an ancestral element which was present before the divergence of the subobscura species cluster.
Paricio
N
N
Departament de Genètica, Facultat de Ciències Biològiques, Universitat de València, Spain.
Martínez-Sebastián
M J
MJ
de Frutos
R
R
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004251:DNA Transposable Elements / Q000235:genetics*; D018076:DNA, Complementary; D004330:Drosophila / Q000235:genetics*; D006570:Heterochromatin / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D014158:Transcription, Genetic; D014960:X Chromosome
D004251:DNA Transposable Elements; D018076:DNA, Complementary; D006570:Heterochromatin