[Heparin-induced thrombocytopenia: review of the literature and description of 2 clinical cases].
We present a literary review regarding heparin-induced thrombocytopenia and we report two cases. The first case regards a female patient with a suspect pulmonary embolism and deep vein thrombosis. Low platelet count was observed already during sub-cutaneous heparin therapy but was aggravated by subsequent intra-venous treatment. The second patient developed thrombocytopenia only after intra-venous heparin infusion while previous sub-cutaneous heparin prophylaxis had not caused low platelet count. In both patients platelet counts normalized rapidly only a few hours after withdrawal of heparin treatment. We therefore point out the importance of the correct monitoring of platelet counts for a timely detection and prevention of heparin-induced thrombocytopenia, and possible consequent paradoxical thrombosis.
Sardeo
C
C
Divisione di Cardiologia, Ospedale Civile di Sondrio.
Fei
C
C
Marlianici
E
E
Giustiniani
S
S
D000368:Aged; D004784:Environmental Monitoring; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D007279:Injections, Subcutaneous; D008875:Middle Aged; D010976:Platelet Count; D013921:Thrombocytopenia / Q000097:blood / Q000139:chemically induced*; D013997:Time Factors
D006493:Heparin
Piastrinopenia indotta da eparina: revisione della letteratura e descrizione di due casi clinici.