[Cutis verticis gyrata and pachydermoperiostosis. Several cases in a same family. Initial results of the treatment of pachyderma with isotretinoin].
This is a case report of four patients of the same family with pachyderma. Their clinical findings are discussed in regard of a review of the literature. Also, because there are few data on effective treatment, their dramatic improvement with isotretinoin is of significant interest.
Centre Hospitalier Universitaire de Sherbrooke, Province de Québec, Canada.
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Beauregard
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D015228:Hypertriglyceridemia / Q000150:complications; D015474:Isotretinoin / Q000627:therapeutic use; D008297:Male; D010004:Osteoarthropathy, Primary Hypertrophic / Q000150:complications / Q000188:drug therapy* / Q000235:genetics; D010375:Pedigree; D012536:Scalp Dermatoses / Q000188:drug therapy* / Q000235:genetics; D012871:Skin Diseases / Q000188:drug therapy* / Q000235:genetics
D015474:Isotretinoin
Cutis verticis gyrata et pachydermopériostose. Plusieurs cas dans une même famille. Résultats préliminaires du traitement de la pachydermie avec l'isotrétinoïne.