Mucosal allergy in the absence of systemic allergy in nasal polyposis and rhinitis: a meta-analysis.
To better determine the role of allergy in rhinitis and nasal polyposis, we assessed the prevalence of nasal mucosal allergy in the absence of systemic allergy. After a thorough literature search we compiled and analyzed data from nine studies (287 patients) that tested for specific immunoglobulin E both intranasally and systemically. When meta-analysis was applied to the different populations, 19% of those who demonstrated specific immunoglobulin E manifested nasal mucosal allergy but no systemic allergy. We suggest that there is an important segment of rhinitis and nasal polyp patients who have nasal mucosal allergy.
Shatkin
J S
JS
Section of Otolaryngology, University of Chicago Hospitals, Illinois.
Delsupehe
K G
KG
Thisted
R A
RA
Corey
J P
JP
D006801:Humans; D006967:Hypersensitivity; D007073:Immunoglobulin E / Q000032:analysis*; D009297:Nasal Mucosa / Q000276:immunology*; D009298:Nasal Polyps / Q000276:immunology*; D011852:Radioallergosorbent Test; D012220:Rhinitis / Q000276:immunology*
D007073:Immunoglobulin E