Obsessive characteristics in subjects with Tourette's syndrome are related to symptoms in their parents.
The symptom characteristics of two Tourette's syndrome (TS) subgroups formed on the basis of their parents' obsessive-compulsive (OC) symptomatology were explored. TS subjects with parents having OC symptoms had significantly more OC symptoms and complex tics and a later age of symptom onset than the balance of the TS cohort. These findings suggest an association between parental OC symptoms and OC symptoms in their TS offspring.
de Groot
C M
CM
Department of Psychiatry, Ohio State University, Columbus 43210.
Bornstein
R A
RA
D000293:Adolescent; D017668:Age of Onset; D002648:Child; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000523:psychology*; D010290:Parents; D011379:Prognosis; D012720:Severity of Illness Index; D005879:Tourette Syndrome / Q000523:psychology*