Octreotide dependency and headache: a case report.
We report on headache induced by a somatostatin octapeptide analog (octreotide) used for the treatment of acromegaly. This "rebound" headache has severe tension-type characteristics and occurs every 6-8 h. It resolves dramatically within minutes with octreotide administration. This is the first report of headache developing under treatment with octreotide.
Department of Neurology, University of Essen, Germany.
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Lederbogen
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Diener
D000172:Acromegaly / Q000188:drug therapy; D000328:Adult; D005260:Female; D006261:Headache / Q000139:chemically induced*; D006801:Humans; D015282:Octreotide / Q000009:adverse effects* / Q000627:therapeutic use; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology
D015282:Octreotide