[Determination of the excretion time of oxytetracycline and lugol in milk of intrauterine treated cows].
Sixteen dairy cows with chronic puerperal endometritis between 3 and 8 weeks post partum were treated with intra-uterine applied oxytetracycline (OTC) and lugol. OTC was rapidly removed from plasma and was not detectable after 48 hours. The concentration of OTC in milk did not exceed 40 micrograms/kg, and it was still detectable in milk 34 hours after treatment. The concentration of OTC in milk was always lower than the limit of 50 micrograms/kg used by milk-testing stations and the European limit (MRL) of 100 micrograms/kg. Milk from cows treated with lugol did not cause inhibition in the plate test.
Dijkstra
T
T
Gezondheidsdienst voor Dieren in Noord-Nederland, Drachten.
Barkema
H W
HW
van Buuren
R D
RD
van Spanje
J G
JG
Jorritsma
H
H
D000287:Administration, Topical; D000818:Animals; D002417:Cattle / Q000378:metabolism*; D002418:Cattle Diseases / Q000188:drug therapy*; D004716:Endometritis / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D017613:Iodine Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics*; D010118:Oxytetracycline / Q000008:administration & dosage / Q000493:pharmacokinetics*; D011644:Puerperal Disorders / Q000188:drug therapy / Q000662:veterinary*; D014599:Uterus
D017613:Iodine Compounds; D010118:Oxytetracycline
Bepaling van de uitscheidingsduur van oxytetracycline en lugol in de melk van intra-uterien behandelde koeien.