Synthesis of novel aminopropylguanidine derivatives with potential antihypertensive activity.
Calis
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Division of Medicinal Chemistry and Pharmaceutics, College of Pharmacy, University of Kentucky, Lexington 40536-0082.
Finch
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JR
Soltis
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EE
Digenis
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GA
D000818:Animals; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000494:pharmacology; D006146:Guanidines / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000494:pharmacology; D007274:Injections, Intraperitoneal; D008297:Male; D051381:Rats; D011918:Rats, Inbred SHR; D013329:Structure-Activity Relationship
D000959:Antihypertensive Agents; D006146:Guanidines