The value of CA 125 measurement before second-look laparotomy in patients with ovarian carcinoma.
Serum CA 125 levels were evaluated in 71 patients undergoing second-look laparotomy for primary epithelial ovarian cancer. With a cut-off limit of 35 U/ml, 17 of 45 patients with residual disease (38%) were CA 125-positive. All of 26 patients with pathological complete response were marker-negative. Second-look laparotomy may be avoided in a select group of patients with elevated CA 125 values.
Finsen Institute, Rigshospitalet, University Hospital, Copenhagen.
U
U
Hørding
K
K
Toftager-Larsen
B
B
Lund
A
A
Dreisler
S
S
Daugaard
F
F
Lundvall
J B
JB
Knudsen
J E
JE
Bock
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018394:CA-125 Antigen / Q000097:blood*; D002277:Carcinoma / Q000097:blood* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007813:Laparotomy; D009367:Neoplasm Staging; D018365:Neoplasm, Residual; D010051:Ovarian Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D012086:Reoperation; D015996:Survival Rate
D018394:CA-125 Antigen