Single amino-acid makes big difference in patent court.
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Swinbanks
D000595:Amino Acid Sequence; D001709:Biotechnology / Q000331:legislation & jurisprudence*; D007564:Japan; D010330:Patents as Topic / Q000331:legislation & jurisprudence*; D010959:Tissue Plasminogen Activator / Q000737:chemistry
D010959:Tissue Plasminogen Activator