Properties of unusual phospholipids, II: Synthesis, NMR studies and monolayer investigations of diacylglycerophosphocholines containing alpha-branched acyl chains.
Diacylglycerophosphocholines, containing various alpha-branched fatty acids, were synthesized and purified to homogeneity. The influence of the alpha-branched acyl chains on the monolayer packing properties of these phospholipids was studied by the Langmuir-Blodgett film balance technique. NMR investigations were used for conformational studies, including the determination of rotamer populations about the dihedral angles (theta 2, theta 4 and alpha 1) in the glycerol region of the diacylglycerophosphocholines.
Rürup
J
J
Bereich Enzymtechnologie/Naturstoffchemie der GBF, Gesellschaft für Biotechnologische Forschung mbH, Germany.
Lauer
F
F
Drewes
A
A
Wray
V
V
Schmid
R D
RD
D005227:Fatty Acids / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D010713:Phosphatidylcholines / Q000138:chemical synthesis / Q000737:chemistry*
D005227:Fatty Acids; D010713:Phosphatidylcholines