Use of desmopressin (DDAVP) in controlling aspirin-induced coagulopathy after cardiac surgery.
Excessive bleeding caused by aspirin therapy in patients undergoing coronary artery bypass surgery is an increasing problem. This case report of six patients illustrates the benefits of using desmopressin to control aspirin-induced coagulopathy. A brief review of the mechanism of coagulation disturbances associated with aspirin and its correction by desmopressin is presented.
Department of Anaesthetics and Resuscitation, Westmead Hospital, NSW, Australia.
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D000368:Aged; D001241:Aspirin / Q000009:adverse effects*; D001780:Blood Coagulation Tests; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001026:Coronary Artery Bypass; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D004211:Disseminated Intravascular Coagulation / Q000139:chemically induced* / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged
D003894:Deamino Arginine Vasopressin; D001241:Aspirin