Efficacy of moxidectin against nematodes in naturally infected sheep.
The activity of an oral drench of moxidectin against nematodes in naturally infected sheep known to harbour Nematodirus species was evaluated at doses of 0.2 and 0.4 mg/kg bodyweight. Moxidectin was 100 per cent effective against nematodes in the abomasum and 100 per cent effective against nematodes in the small intestine except for adult Trichostrongylus species, against which its efficacy was 94 per cent. It was 100 per cent effective against nematodes in the large intestine except for Trichuris ovis, against which its efficacy was 83 per cent.
Coles
G C
GC
Department of Veterinary and Animal Science, University of Massachusetts at Amherst.
Giordano-Fenton
D J
DJ
Tritschler
J P
JP
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology* / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy* / Q000469:parasitology; D018942:Macrolides; D009348:Nematoda / Q000187:drug effects; D009349:Nematode Infections / Q000188:drug therapy* / Q000469:parasitology; D010270:Parasite Egg Count / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000469:parasitology
D000871:Anthelmintics; D000900:Anti-Bacterial Agents; D018942:Macrolides; C027837:moxidectin