Effects of prenatal exposure to 50 Hz magnetic fields on development in mice: I. Implantation rate and fetal development.
Pregnant CD1 mice were exposed or sham-exposed from day 0 to day 17 of gestation to a 50 Hz sinusoidal magnetic field at 20 mT (rms). Preimplantation and postimplantation survival were assessed and fetuses examined for the presence of gross external, internal, and skeletal abnormalities. There were no statistically significant field-dependent effects on preimplantation or postimplantation survival, sex ratio, or the incidence of fetuses with internal or skeletal abnormalities. Magnetic field exposure was, however, associated with longer and heavier fetuses at term, with fewer external abnormalities. The results lend no support to suggestions of increased rates of spontaneous abortion or congenital malformation following prenatal exposure to power frequency magnetic fields.
National Radiological Protection Board, Didcot, Oxon, United Kingdom.
C I
CI
Kowalczuk
L
L
Robbins
J M
JM
Thomas
B K
BK
Butland
R D
RD
Saunders
D000016:Abnormalities, Radiation-Induced; D000818:Animals; D000831:Animals, Newborn; D010064:Embryo Implantation; D005314:Embryonic and Fetal Development / Q000528:radiation effects*; D005260:Female; D005313:Fetal Death; D005333:Fetus / Q000502:physiology / Q000528:radiation effects; D008280:Magnetics; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011247:Pregnancy; D012016:Reference Values