Dermatomyositis with multiple skin ulcers showing vasculitis and membrano-cystic lesion.
A 63-year-old woman with dermatomyositis (DM) developed multiple punched-out ulcers of the skin. She had not only a past history of gastric cancer 10 years prior to the onset of DM, but also a familial history of cancer. A skin biopsy from one of the ulcers revealed both vasculitis and membrano-cystic lesion in the same specimen. She died of interstitial pneumonitis one year after the onset of DM. Vasculitis and membrano-cystic lesion may be an important marker of a poor prognosis in DM.
Yamamoto
T
T
Department of Dermatology, Tokyo Metropolitan Bokuto Hospital, Japan.
Ohkubo
H
H
Katayama
I
I
Nishioka
K
K
D003882:Dermatomyositis / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000150:complications* / Q000473:pathology; D012883:Skin Ulcer / Q000150:complications* / Q000473:pathology; D014657:Vasculitis / Q000150:complications* / Q000473:pathology