Neurourologic consequences of accidental intrathecal vincristine: a case report.
Inadvertent intrathecal administration of vincristine results in severe neurotoxicity. Motor and sensory bladder dysfunction have been reported but the long-term urologic consequences are unknown due to the associated high mortality. We report a case of accidental intrathecal vincristine administration with patient survival and follow-up of 24 months. The child developed a lower motor neuron neuropathic bladder requiring intermittent self-catheterization of the bladder. Urinary tract management of these children should be based on the urodynamic findings.
Department of Surgery, University of Michigan, Ann Arbor.
M R
MR
Zaragoza
M L
ML
Ritchey
A
A
Walter
D002648:Child; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D008508:Medication Errors; D001750:Urinary Bladder, Neurogenic / Q000139:chemically induced*; D014750:Vincristine / Q000633:toxicity*
D014750:Vincristine