Taxol content of stored fresh and dried Taxus clippings.
The taxol content of dried Taxus biomass was monitored monthly for 15 months. Intact and finely ground biomass was stored at room temperature (22 degrees-24 degrees) as well as under refrigeration (2 degrees-4 degrees). In addition, intact fresh clippings stored under refrigeration in sealed plastic bags for up to 10 weeks were evaluated for changes in taxol content. Analysis indicates that properly dried Taxus clippings can be stored either intact or powdered at room temperature or under refrigeration with no apparent loss of taxol content. The taxol content in fresh intact clippings was also stable for at least 10 weeks when stored under refrigeration.
Research Institute of Pharmaceutical Sciences, University of Mississippi, University 38677.
H N
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elSohly
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Croom
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el-Kashoury
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elSohly
J D
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McChesney
D018533:Biomass; D002851:Chromatography, High Pressure Liquid; D017239:Paclitaxel / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D018515:Plant Leaves / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D012034:Refrigeration
D017239:Paclitaxel