[Lysis of cytostatic drug-associated axillary vein thrombosis].
A 3 years old patient receiving chemotherapy for acute-lymphoblastic leukemia according to the ALL-BFM 90-treatment protocol developed thrombosis of the vena axillaris. Without removing the central venous catheter located at the site of thrombosis it was possible to lyse the thrombus by the systemic application of recombinant human tissue-type plasminogen activator (rt-PA). The method is recommended for the treatment of thrombotic occlusions in children.
Universitäts-Kinderklinik Göttingen.
A
A
Pekrun
H
H
Schiffmann
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M
Lakomek
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D000990:Antithrombin III / Q000008:administration & dosage; D001367:Axillary Vein / Q000000981:diagnostic imaging / Q000187:drug effects*; D001780:Blood Coagulation Tests; D002675:Child, Preschool; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000188:drug therapy*; D011859:Radiography; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000097:blood / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*
D000990:Antithrombin III; D006493:Heparin; D010959:Tissue Plasminogen Activator
Lysierung einer Cytostatica-assoziierten Vena axillaris-Thrombose.