Structural features and anti-complementary activity of rehmannan SA, a polysaccharide from the root of Rehmannia glutinosa.
The structural features of rehmannan SA, a polysaccharide with remarkable reticuloendothelial system-potentiating activity obtained from the root of Rehmannia glutinosa, were investigated by methylation analysis and periodate oxidation. Rehmannan SA is mainly made up of arabino-3,6-galactan type structural units. Both rehmannan SA and rehmannan SB showed pronounced anti-complementary activity.
Kyoritsu College of Pharmacy, Tokyo, Japan.
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Tomoda
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Miyamoto
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Shimizu
D000818:Animals; D002240:Carbohydrate Sequence; D015941:Complement Hemolytic Activity Assay; D003165:Complement System Proteins / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D008969:Molecular Sequence Data; D011134:Polysaccharides / Q000737:chemistry* / Q000494:pharmacology; D012756:Sheep; D013329:Structure-Activity Relationship
D004365:Drugs, Chinese Herbal; D011134:Polysaccharides; D003165:Complement System Proteins