A case of viral encephalitis with hyperthermia and status epilepticus: efficacy of dantrolene treatment.
A case of viral encephalitis is described. A 55-year-old female developed hyperthermia and status epilepticus. Herpes simplex virus was regarded as a factor since viral complex titres were elevated and decreased. In addition to acyclovir and anticonvulsive agents, dantrolene (150 mg/day) was administered orally through a nasogastric tube for heat stroke. Convulsions and hyperthermia gradually decreased and intravenous agents were replaced by oral agents. Dantrolene may be a useful adjuvant in hyperthermia and convulsions associated with encephalitis.
Department of Anaesthesiology and Reanimatology, Fukui Medical School, Japan.
K
K
Nakajima
J
J
Harada
K
K
Takahashi
Y
Y
Goto
D000927:Anticonvulsants / Q000627:therapeutic use; D003620:Dantrolene / Q000627:therapeutic use*; D018792:Encephalitis, Viral / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D005334:Fever / Q000150:complications* / Q000188:drug therapy*; D006561:Herpes Simplex / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D013226:Status Epilepticus / Q000150:complications* / Q000188:drug therapy*; D013874:Thiopental / Q000627:therapeutic use
D000927:Anticonvulsants; D003620:Dantrolene; D013874:Thiopental