title: Early experience with the Jyros bileaflet valve in the mitral position: high incidence of valve thrombosis.
abstract: The Jyros valve is a new bileaflet valve with the unusual feature that the hinge is expected to rotate continuously inside the housing. Nine isolated Jyros mitral prostheses were implanted from July to October 1993. All patients survived the surgical procedure and during the follow up underwent transthoracic (TTE) and transesophageal echocardiograms (TEE) for the evaluation of hinge rotation. Neither TTE nor TEE were able to show hinge rotation in any patient at any time. Five patients had prosthetic thrombosis. In the successfully treated with thrombolysis. In the remaining patient thrombolysis was contraindicated. Eight patients are alive; one died of gastro-intestinal bleeding a few months after discharge. The absence of hinge rotation may be the triggering mechanism of valve thrombosis although no explanted prostheses were available for examination. Further studies are necessary to understand the mechanism of valve thrombosis with the Jyros bileaflet prosthesis.
authors.affiliation: Department of Cardiac Surgery, Medical School, Second University of Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Renzulli
authors.forename: N
authors.initials: N
authors.lastname: Vitale
authors.forename: A
authors.initials: A
authors.lastname: Caruso
authors.forename: F
authors.initials: F
authors.lastname: Covino
authors.forename: F
authors.initials: F
authors.lastname: De Vivo
authors.forename: L
authors.initials: L
authors.lastname: Piazza
authors.forename: M
authors.initials: M
authors.lastname: Cotrufo
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D004452:Echocardiography; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve; D011474:Prosthesis Design; D013927:Thrombosis / Q000209:etiology*
chemical_list: D000925:Anticoagulants