title: Assessment of intravenous streptokinase therapy in acute myocardial infarction.
abstract: Ten patients presenting within 6 hours of myocardial infarction, without contraindication for thrombolytic therapy, were given intravenous (IV) streptokinase (STK) 750,000 units in 15-30 min by infusion followed by anticoagulant therapy. Treatment was started within 241-360 min after the onset of symptoms. Fifteen other patients were given standard treatment without STK. Reperfusion was observed after a mean duration of 46 min in 7 patients in the STK group and none in the non-STK group. The results of IV STK thrombolytic therapy are comparable with those of previous studies using IV STK.
authors.affiliation: SMS Medical College and Hospital, Jaipur.
authors.forename: P
authors.initials: P
authors.lastname: Garg
authors.forename: R
authors.initials: R
authors.lastname: Saigal
authors.forename: S C
authors.initials: SC
authors.lastname: Mathur
mesh_terms: D000328:Adult; D000368:Aged; D003326:Coronary Circulation / Q000187:drug effects; D005260:Female; D006801:Humans; D007194:India; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000008:administration & dosage* / Q000009:adverse effects; D015912:Thrombolytic Therapy
chemical_list: D013300:Streptokinase