[Peridural morphine administration in restless legs status].
The restless-legs syndrome is known to occur in a familial form. The paraesthesias, which are hard to define, are sometimes compared to a painful sensation that can be alleviated only by movement. The pathomechanism of the syndrome and its aetiology are still unknown. A 67-year old patient was admitted as an emergency with most severe pain in her legs. In her family the syndrome occurred in an autosomal dominant form. A long-standing history of abuse of various analgesics was known. Initially the symptoms could not be influenced by any of the various drugs given; even epidural bupivacaine showed no effect. Dramatic relief, however, was obtained by epidural morphine. The maintenance therapy with oral morphine sulfate provided equally good results.
Vahedi
H
H
Institut für Anästhesiologie und operative Intensivmedizin, Zentralklinikum, Augsburg.
Küchle
M
M
Trenkwalder
C
C
Krenz
C J
CJ
D000284:Administration, Oral; D000368:Aged; D015360:Analgesia, Epidural; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D004305:Dose-Response Relationship, Drug; D004630:Emergencies; D005260:Female; D005799:Genes, Dominant / Q000235:genetics; D006801:Humans; D009020:Morphine / Q000008:administration & dosage*; D012148:Restless Legs Syndrome / Q000188:drug therapy* / Q000235:genetics
D009020:Morphine
Peridurale Morphiumanwendung bei Restless-Legs-Status.