title: Feto-maternal alloimmune thrombocytopenia associated with anti-HPA-5a--the first Australian case.
abstract: Maternal alloantibodies to platelet specific antigens are a rare but important cause of severe thrombocytopenia in the fetus and neonate. Feto-Maternal Alloimmune Thrombocytopenia (FMAT) is most often due to anti-HPA-1a (PLA-1) or anti-HPA-5b (Bra). Anti-HPA-5a (Brb) however is extremely uncommon, with only 4 cases previously described. We report the first Australian case of feto-maternal alloimmune thrombocytopenia due to anti-HPA-5a.
authors.affiliation: Department of Pathology, King Edward Memorial Hospital for Women.
authors.forename: T S
authors.initials: TS
authors.lastname: Roper
authors.forename: J A
authors.initials: JA
authors.lastname: Lown
authors.forename: A L
authors.initials: AL
authors.lastname: Barr
mesh_terms: D000328:Adult; D016824:Antigens, Human Platelet / Q000276:immunology*; D001315:Australia; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000276:immunology*; D011247:Pregnancy; D013921:Thrombocytopenia / Q000276:immunology*
chemical_list: C071092:5a alloantigen, human; D016824:Antigens, Human Platelet