title: [Comparative study of intravenous anesthesia with propofol in continuous perfusion and neuroleptanalgesia in traumatology surgery].
abstract: OBJECTIVE. To study propofol as the single agent for both anesthetic induction and maintenance with respect to quality of anesthesia, hemodynamic effects, quality of recovery and analgesic requirements in comparison with neuroleptoanesthesia as the technique of reference. PATIENTS AND METHODS. We selected 2 homogeneous groups of 15 ASA I-III patients undergoing traumatological surgery. Patients were premedicated with bromazepam 3 mg p.o. and droperidol 0.03 mg/kg prior to induction. Induction was achieved with propofol 1.5-2.5 mg/kg in group I (GI) and with sodium thiopental 4-5 mg/kg in group II (GII). Maintenance was by continuous infusion of propofol 6-12 mg/kg in GI and with droperidol 0.15 microgram/kg/h and 50% N2O/O2 in GII. Both groups received fentanyl 4 micrograms/kg/h. Neither analgesia nor curarization were antagonized pharmacologically. Variables recorded were time and quality of anesthetic induction, mean duration of anesthesia, anesthetic education time, time until orientation and time of residual analgesia. Hemodynamic parameters were recorded for both groups at baseline, after induction, at intubation, at 2 and 5 min after intubation, at the start of surgical incision, 30 min after start of incision, and at the end of surgery. Results for the two groups were compared, as were results at the various moments of measurement within groups.
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital Universitario de Puerto Real, Cadiz.
authors.forename: J L
authors.initials: JL
authors.lastname: Ortega
authors.forename: D
authors.initials: D
authors.lastname: Segura
authors.forename: F
authors.initials: F
authors.lastname: Neira
authors.forename: M L
authors.initials: ML
authors.lastname: Martín
authors.forename: G
authors.initials: G
authors.lastname: Sánchez
authors.forename: M S
authors.initials: MS
authors.lastname: Carrasco
mesh_terms: D000328:Adult; D000771:Anesthesia, Intravenous; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009458:Neuroleptanalgesia; D015742:Propofol / Q000494:pharmacology; D014947:Wounds and Injuries / Q000601:surgery*
chemical_list: D015742:Propofol
vernacular_title: Estudio comparativo entre la anestesia intravenosa con propofol en perfusión continua y la neuroleptoanalgesia en cirugía traumatológica.