title: Clinical evaluation of a new type of centrifugal pump.
abstract: The major problems with existing centrifugal pumps are leakage, mechanical trauma, and thrombus formation. In consideration of these problems, a new compact centrifugal pump system was developed. The purpose of this study was to evaluate the new centrifugal pump system clinically. Ten patients underwent open heart surgery with a centrifugal pump or a roller pump. During surgery, hemodynamic and hematological data were obtained. A pulsatile assist device in the pump circuit was used in patients with severe heart disease. There was neither operative death nor hospital mortality, and there was no difference with regard to hemodynamic data between the two groups. The centrifugal pump groups, however, had significantly lower hemolysis, especially during prolonged cardiopulmonary bypass. This centrifugal pump could also create sufficient pulsatile flow with a pulsatile assist device. Postoperative macroscopic and microscopic findings demonstrated the smooth surface of the pump without thrombus formation. This centrifugal pump system might be useful for prolonged cardiopulmonary bypass.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Nippon Medical School, Tokyo, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Ninomiya
authors.forename: T
authors.initials: T
authors.lastname: Shoji
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Ikeshita
authors.forename: M
authors.initials: M
authors.lastname: Ochi
authors.forename: S
authors.initials: S
authors.lastname: Yamauchi
authors.forename: T
authors.initials: T
authors.lastname: Yajima
authors.forename: H
authors.initials: H
authors.lastname: Yamauchi
authors.forename: T
authors.initials: T
authors.lastname: Sugimoto
authors.forename: T
authors.initials: T
authors.lastname: Aizawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006353:Heart-Assist Devices / Q000009:adverse effects; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D006801:Humans; D008875:Middle Aged; D011673:Pulsatile Flow
chemical_list: D006454:Hemoglobins