[A comparative evaluation of the antacid properties of the preparations Maalox and Almagel].
Basic modes of action and indications for aluminium and magnesium-containing antacids are reviewed. Antacid properties of Maalox were studied versus those of Almagel in 24 duodenal ulcer patients by the following indices of pH-metry: time of pH response onset, "alkaline time", alkalification area and index. All the features were significantly different when assessed in the body of the stomach. Regular Maalox intake as a main medicine provided good results in the treatment of duodenal ulcer (25 responders), gastric ulcer (14 responders), erosive gastroduodenitis (14 responders), erosive reflux-esophagitis (9 responders). Maalox displayed high symptomatic efficacy, safety, insignificant side effects.
Grebenev
A L
AL
Sheptulin
A A
AA
Okhlobystin
A V
AV
D000328:Adult; D000536:Aluminum Hydroxide / Q000009:adverse effects / Q000627:therapeutic use*; D000863:Antacids / Q000009:adverse effects / Q000627:therapeutic use*; D001566:Benzocaine / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000503:physiopathology; D004942:Esophagitis, Peptic / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D005745:Gastric Acidity Determination; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008276:Magnesium Hydroxide / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D013276:Stomach Ulcer / Q000188:drug therapy / Q000503:physiopathology
D000863:Antacids; D004338:Drug Combinations; C010016:aluminum hydroxide, benzocaine, magnesium hydroxide drug combination; C013591:aluminum hydroxide, magnesium hydroxide, drug combination; D000536:Aluminum Hydroxide; D008276:Magnesium Hydroxide; D001566:Benzocaine
Sravnitel'naia otsenka antatsidnykh svoĭstv preparatov "Maaloks" i "Al'magel'".