title: [Clinical studies in prostatic carcinoma].
abstract: Carcinoma of the prostate is a widespread disease posing serious problems, especially when patient in stage T3-T4 are concerned. Proceeding from clinical observations on 269 patients presenting the aforementioned condition, and on the basis of thorough clinical, laboratory and histologic studies, a combined therapeutic approach using cyproterone acetate is adopted, supplemented by orchiectomy in some patients, and transurethral resection in others. After 3-month treatment course, changes in the level of microelements, copper, zinc and iron in particular, are recorded. In some cases the level of prostate specific antigen is lowered. Control of the underlying disease is successfully attained in 72 per cent of the patients.
authors.forename: Kh
authors.initials: Kh
authors.lastname: Kumanov
authors.forename: M
authors.initials: M
authors.lastname: Tsvetkov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D017373:Cyproterone Acetate / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009919:Orchiectomy; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology / Q000628:therapy*; D012074:Remission Induction
chemical_list: D007987:Gonadotropin-Releasing Hormone; D017373:Cyproterone Acetate
vernacular_title: Klinichni prouchvaniia pri kartsinoma na prostatnata zhleza.