Cancer genetics.
The fundamental ideas on the causes of cancer have been known for some time. They can now be interpreted in terms of the notion that cancer is essentially a genetic disease at the cellular level. The aim of this introductory article is to provide a brief overview of these ideas and the evidence for them, as well as some of the implications for future approaches to the prevention, early detection and treatment of cancer.
Bodmer
W F
WF
Imperial Cancer Research Fund, London, UK.
D005190:Family; D016147:Genes, Tumor Suppressor; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D009857:Oncogenes; D010677:Philadelphia Chromosome; D014178:Translocation, Genetic