Papaverine-induced mydriasis.
Five cases of ipsilateral pupillary dilatation that developed during local intraarterial infusion of papaverine are reported. All patients were being treated for symptomatic vasospasm secondary to subarachnoid hemorrhage. In each case, the tip of the infusion catheter was positioned in the internal carotid artery in close proximity to the ostium of the ophthalmic artery. Pupillary dilatation in all patients readily resolved after termination of the infusion.
Hendrix
L E
LE
Department of Radiology, University of Virginia Health Sciences Center, Charlottesville.
Dion
J E
JE
Jensen
M E
ME
Phillips
C D
CD
Newman
S A
SA
D000328:Adult; D000368:Aged; D002343:Carotid Artery, Internal; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D002546:Ischemic Attack, Transient / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D015878:Mydriasis / Q000139:chemically induced*; D009880:Ophthalmic Artery; D010208:Papaverine / Q000008:administration & dosage / Q000009:adverse effects*; D013345:Subarachnoid Hemorrhage / Q000628:therapy
D010208:Papaverine