title: [Cardiac arrhythmia with oral oxamniquine use in the schistosomiasis mansoni treatment].
abstract: The authors report a case of a patient with schistosomiasis (S. mansoni) treated with one single dose (15 mg/kg/BWT) of oral oxamniquine who presented Mobitz type I second-degree AV block and sinus arrest with ventricular escape as a side-effect. They conclude that in spite of the safety and good activity of oxamniquine it may be a determinant of cardiotoxicity.
authors.affiliation: Departamento Materno-Infantil e Saúde-Comunitária, Universidade Estadual de Londrina, Paraná, Brasil.
authors.forename: J C
authors.initials: JC
authors.lastname: Guitti
authors.forename: L N
authors.initials: LN
authors.lastname: Gordan
authors.forename: J L
authors.initials: JL
authors.lastname: Baldy
mesh_terms: D000284:Administration, Oral; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D002648:Child; D004562:Electrocardiography; D006327:Heart Block / Q000139:chemically induced; D006801:Humans; D008297:Male; D010073:Oxamniquine / Q000008:administration & dosage / Q000009:adverse effects*; D012555:Schistosomiasis mansoni / Q000188:drug therapy*
chemical_list: D010073:Oxamniquine
vernacular_title: Arritmia cardíaca com uso de oxamniquine oral no tratamento de esquistossomose mansônica.