Inhibition of hepatic extramedullary haemopoiesis by nucleoprotein of heterologous rotavirus strain in infant mice.
Infant mice (NMRI strain) showed the inhibition of hepatic extramedullary haemopoiesis by oral inoculation of a 100 ID50 dose of EB rotavirus and nucleoprotein of SA-11 rotavirus (serotype 3). The extramedullary haemopoiesis was observed by oral inoculation of surface protein VP7 of SA-11 rotavirus and in control (placebo administered) mice.
Kanwar
S S
SS
Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Singh
V
V
Mehta
S K
SK
Malik
A K
AK
Vinayak
V K
VK
Pal
S R
SR
Mehta
S
S
D000818:Animals; D000956:Antigens, Viral; D002213:Capsid / Q000494:pharmacology; D036022:Capsid Proteins; D006411:Hematopoiesis, Extramedullary / Q000187:drug effects*; D008099:Liver / Q000473:pathology; D051379:Mice; D008815:Mice, Inbred Strains; D009698:Nucleoproteins / Q000494:pharmacology*; D012401:Rotavirus / Q000737:chemistry*; D012400:Rotavirus Infections / Q000097:blood* / Q000473:pathology; D014764:Viral Proteins / Q000494:pharmacology*
D000956:Antigens, Viral; D036022:Capsid Proteins; D009698:Nucleoproteins; C050779:VP7 protein, Rotavirus; D014764:Viral Proteins