title: Anaplastic large-cell lymphoma presenting primarily in bone in a patient with AIDS.
abstract: Non-Hodgkin's lymphomas have been recognized as an important and frequently fatal part of the spectrum of diseases associated with HIV infection. These are most often high-grade B-cell lymphomas usually of immunoblastic and small cell non-cleaved subtypes. Sporadic reports of T-cell lymphomas associated with HIV infection are found in the literature. Two have been reported to be CD30 positive presenting with lymph node and skin involvement. We report a case of an AIDS patient with a T-cell anaplastic large-cell lymphoma that was CD30-positive and presented in bone. This is most probably a sporadic event rather than another part of the AIDS-associated spectrum of disease.
authors.affiliation: University of Utah School of Medicine, Department of Pathology, Salt Lake City.
authors.forename: T A
authors.initials: TA
authors.lastname: Piira
authors.forename: K
authors.initials: K
authors.lastname: Ries
authors.forename: C R
authors.initials: CR
authors.lastname: Kjeldsberg
authors.forename: S L
authors.initials: SL
authors.lastname: Perkins
mesh_terms: D001859:Bone Neoplasms / Q000473:pathology*; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000473:pathology*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000473:pathology*; D008297:Male; D008875:Middle Aged