title: [Functional status of thrombocytes in men and women in younger age groups].
abstract: Differences in the functional status of platelets in vitro were compared between young adult men and women. Platelets in women were found to have a higher susceptibility to ADP, epinephrine, arachidonic acid and to produce more TXB2. These changes appear to be due to the declined hematocrit and thus to lower concentrations of sodium citrate, a commonly used anticoagulant. Platelet activity was conversely related to plasma sodium citrate. Since calcium chloride was found to offset the inhibitory effect of sodium citrate, it was assumed that the sex-related differences observed in platelet activity were due to varied levels of ionized calcium. The platelet activity was at equal values of hematocrit equal in both sexes. (Tab. 3, Ref. 19.).
authors.affiliation: Výskumný ústav gerontológie v Malackách, Slovakia.
authors.forename: D
authors.initials: D
authors.lastname: Kasjanovová
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000378:metabolism / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D012016:Reference Values; D013929:Thromboxane B2 / Q000096:biosynthesis
chemical_list: D013929:Thromboxane B2
vernacular_title: Funkcný stav trombocytov u muzov a źien mladej vekovej skupiny.