Fungal metabolites. XIII. Isolation and structural elucidation of new peptaibols, trichodecenins-I and -II, from Trichoderma viride.
Three new groups of peptaibols, trichodecenins, trichorovins and trichocellins, have been isolated from conidia of the fungus, Trichoderma viride. The structures of trichodecenins-I and -II were established by positive-ion fast-atom bombardment, collision-induced dissociation mass spectrometry and two-dimensional NMR spectroscopy. Trichodecenins-I and -II have a (Z)-4-decenoyl group, six amino acid residues and a leucinol moiety in the molecules. Trichodecenin-II was synthesized by the solution-phase method.
Fujita
T
T
Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
Wada
S
S
Iida
A
A
Nishimura
T
T
Kanai
M
M
Toyama
N
N
D000595:Amino Acid Sequence; D005231:Fatty Acids, Unsaturated / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry* / Q000302:isolation & purification; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014242:Trichoderma / Q000737:chemistry*
D005231:Fatty Acids, Unsaturated; D009842:Oligopeptides; C087389:trichodecenin II; C087388:trichodecenin I