title: [The peripheral blood of frogs in the genus Rana as a test system for assessing environmental pollution].
abstract: Differential analysis of leukocytes was carried out peripheral blood smears of the frogs from four localities in the territory adjacent to a chemical plant in the Novgorod District (Rana temporaria) and two localities with an increased radiation background in the Bryansk District (R. lessonae and R. esculenta). Marked and similar changes in the content of neutrophilic and eosinophilic granulocytes were found in the frogs from all studied localities. A pronounced neutropenia was noted, which was often accompanied by the appearance of immature forms of the neutrophilic series. We propose that these changes are due selective damage of the entire series of differentiation of neutrophilic granulocytes, including the precursor cells. The increased percentage of eosinophilic granulocytes and appearance, in some cases, of immature cells are considered as signs of protective (antitoxic and antimicrobial) response.
authors.forename: E V
authors.initials: EV
authors.lastname: Chernyshova
authors.forename: V I
authors.initials: VI
authors.lastname: Starostin
mesh_terms: D000818:Animals; D004784:Environmental Monitoring / Q000379:methods*; D004785:Environmental Pollutants / Q000633:toxicity*; D007958:Leukocyte Count / Q000187:drug effects / Q000528:radiation effects; D007962:Leukocytes / Q000187:drug effects* / Q000528:radiation effects*; D011893:Rana esculenta; D011896:Rana temporaria; D011898:Ranidae / Q000097:blood*; D012426:Russia
chemical_list: D004785:Environmental Pollutants
vernacular_title: Perifericheskaia krov' liagushek roda Rana kak test-sistema dlia otsenki zagriazneniia okruzhaiushcheĭ sredy.