title: Cytomorphology and immunocytochemistry in the diagnosis of non-Hodgkin lymphomas.
abstract: 1. Lymph node aspirates from 17 patients with an initial cytologic diagnosis of lymphoma (11 cases) or with suspected lymphoma (6 cases) were studied by immunocytochemistry, which led to a final diagnosis. Immunocytochemical staining demonstrated a B-cell phenotype in 10 cases, one case of anaplastic large cell Ki-1+ lymphoma, one lymphoblastic lymphoma negative for B and T cell markers, one large-cell unclassified lymphoma, and one inconclusive case. Three of the cases with suspected lymphoma were diagnosed as reactive lymphadenitis. 2. Combined cytomorphology and cytochemistry permitted a conclusive diagnosis in 13 out of 14 cases of lymphoma. Histology and immunohistochemistry confirmed the cytologic diagnosis. The inconclusive case was diagnosed as a T pleomorphic, small-cell lymphoma by histology. 3. The accuracy of cytomorphology associated with immunocytochemistry is high. However, the diagnosis of low-grade lymphomas, especially of a T phenotype may be difficult.
authors.affiliation: Departamento de Anatomia Patológica, Faculdade de Medicina, Universidade Federal da Bahia, Salvador, Brasil.
authors.forename: H
authors.initials: H
authors.lastname: Schaer-Barbosa
authors.forename: M
authors.initials: M
authors.lastname: Sadigursky
authors.forename: A L
authors.initials: AL
authors.lastname: Bittencourt
mesh_terms: D001707:Biopsy, Needle; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000473:pathology