[Receptors for the Fc fragment of IgG (RFc gamma): membrane forms and soluble forms].
Membrane and soluble forms of Fc gamma receptors play important role in immune reactions. Upon interaction with immune complexes, Fc gamma R transduce activation or inhibition signals via their intracytoplasmic portions. Soluble Fc gamma R contain the Fc gamma R ectodomain. They bind to the Fc portion of IgG and inhibit Fc dependent immune reactions. In addition, they bind directly to various cell types and regulate immune reactions.
Sautès
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INSERM Unité 255, Immunologie Cellulaire et Clinique, Institut Curie, Paris.
Fridman
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D000818:Animals; D006801:Humans; D015471:Leukemia, Basophilic, Acute / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000473:pathology; D051379:Mice; D051381:Rats; D017452:Receptors, IgG / Q000276:immunology / Q000378:metabolism* / Q000648:ultrastructure*; D015398:Signal Transduction; D012995:Solubility; D014407:Tumor Cells, Cultured / Q000378:metabolism
D017452:Receptors, IgG
Les récepteurs pour le fragment Fc des IgG (RFc gamma): formes membranaires et formes solubles.