Neutrophilic dermatosis: a case of overlapping syndrome with monoclonal antineutrophil cytoplasmic autoantibody activity.
A 66-year-old male patient presented, over a 10-year period, polymorphic cutaneous manifestations with extensive neutrophilic infiltration which supports the diagnosis of overlapping syndrome of neutrophilic dermatoses. This was associated with a benign monoclonal gammopathy of IgA lambda type that had antineutrophil cytoplasmic autoantibody (ANCA) activity. Neutrophilic dermatoses may be associated with or can trigger ANCA.
Bayle
P
P
Service de Dermatologie, Hôpital Purpan, Toulouse, France.
Laplanche
G
G
Gorguet
B
B
Oksman
F
F
Boulinguez
S
S
Bazex
J
J
D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic; D000911:Antibodies, Monoclonal / Q000032:analysis*; D001323:Autoantibodies / Q000032:analysis*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D010265:Paraproteinemias / Q000150:complications*; D016463:Sweet Syndrome / Q000150:complications* / Q000276:immunology / Q000473:pathology
D019268:Antibodies, Antineutrophil Cytoplasmic; D000911:Antibodies, Monoclonal; D001323:Autoantibodies; D007070:Immunoglobulin A