[The isolation and identification of qianhucoumarin B and qianhucoumarin C from Peucedanum praeruptorum].
Five compounds were isolated from the traditional Chinese medicine Qianhu, roots of Peucedanum praeruptorum. Their structures were identified as 3'-angeloyloxykhellactone (IX), qianhucoumarin B (X), qianhucoumarin C (XI), Pd-III (XIII) and peucedanocoumarin III (XV). Among them, X and XI are new compounds, their absolute configurations were elucidated by chemical correlation with khellactones, as 3'(S)-acetoxy-4'(S)-hydroxy-3',4'-dihydroseselin(X) and 3'(S)-hydroxy-4'(S)-acetoxy-3',4'-dihydroseselin (XI). Compound IX was isolated from plants for the first time.
Kong
L Y
LY
Research Department of Natural Drugs, Shenyang College of Pharmacy.
Pei
Y H
YH
Li
X
X
Wang
S X
SX
Hou
B L
BL
Zhu
T R
TR
D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D015394:Molecular Structure
D003374:Coumarins; D004365:Drugs, Chinese Herbal; C087795:qianhucoumarin C; C087794:qianhucoumarin B