Spermine effect on the binding of casein kinase I to the rat liver mitochondrial structures.
The results indicated here, together with those previously reported, show that spermine, ubiquitous polyamine, while promoting the transmembrane translocation of casein kinase II (CKII) across the outer membrane to more internal compartments of rat liver mitochondria, promotes the binding of casein kinase I (CKI) to the external surface of outer mitochondrial membrane but inhibits its spontaneously occurring binding to more internal structures.
Clari
G
G
Dipartimento di Chimica Biologica, Università di Padova, Italy.
Toninello
A
A
Bordin
L
L
Cattapan
F
F
Piccinelli-Siliprandi
D
D
Moret
V
V
D000818:Animals; D047388:Casein Kinases; D007425:Intracellular Membranes / Q000187:drug effects / Q000201:enzymology; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000201:enzymology; D011494:Protein Kinases / Q000378:metabolism*; D051381:Rats; D013096:Spermine / Q000494:pharmacology*; D013379:Substrate Specificity
D013096:Spermine; D011494:Protein Kinases; D047388:Casein Kinases