title: Low prevalence of antibody to human parvovirus B19 in Singapore.
abstract: A seroepidemiological survey was conducted in Singapore to assess the prevalence of antibody to human parvovirus B19. Sera were collected from 600 healthy individuals between 6 months and over 50 years of age and tested for IgG antibody against B19 virus by antigen capture indirect immunosorbent assay. The overall seropositivity rate was 16.2%. All the children under 5 years of age were seronegative. Antibody prevalence increased gradually from 3.5% in school children (5-14 years of age) to 7.7% in age group 15-19 years and then to 10.3% in young adults (20-24 years of age). In the age group 25-34 years the prevalence was 28% and in the age group over 35 years 65% had parvovirus B19 antibody. The results of the survey indicate that there has been very low incidence of B19 virus infection in Singapore during the last two decades.
authors.affiliation: Department of Epidemiology, National Institute of Health, Tokyo.
authors.forename: Y
authors.initials: Y
authors.lastname: Matsunaga
authors.forename: K T
authors.initials: KT
authors.lastname: Goh
authors.forename: E
authors.initials: E
authors.lastname: Utagawa
authors.forename: N
authors.initials: N
authors.lastname: Muroi
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D016731:Erythema Infectiosum / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007163:Immunosorbent Techniques; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D016732:Parvovirus B19, Human / Q000276:immunology*; D015995:Prevalence; D012846:Singapore / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G