Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part II).
The second part of this review on eosinophils focuses on biological cell functions and surveys the various deleterious mechanisms involved in the eosinophil-dominated inflammatory reaction. It discusses the possible pathogenic role of eosinophils in several eosinophil-related diseases, such as parasitic infections, interstitial lung disorders and bronchial diseases, such as parasitic infections, interstitial lung disorders and bronchial diseases, graft rejection, vasculitic granulomatous disorders, pleural effusion, and bronchogenic tumours. The final section of the article highlights the possible recent pharmacological and future therapeutic approaches in modifying eosinophil recruitment and function.
Kroegel
C
C
Department of Pneumology, Albert-Ludwigs-University, Freiburg, Germany.
Warner
J A
JA
Virchow
J C
JC
Matthys
H
H
D004804:Eosinophils / Q000187:drug effects / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000276:immunology; D008171:Lung Diseases / Q000188:drug therapy / Q000276:immunology*