title: Inhibitors of cyclic nucleotide phosphodiesterase isoenzymes--their potential utility in the therapy of asthma.
authors.affiliation: Organon International BV, Scientific Development Group, Oss, The Netherlands.
authors.forename: C D
authors.initials: CD
authors.lastname: Nicholson
authors.forename: M
authors.initials: M
authors.lastname: Shahid
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D000818:Animals; D001249:Asthma / Q000188:drug therapy* / Q000201:enzymology*; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*
chemical_list: D007527:Isoenzymes; D010726:Phosphodiesterase Inhibitors; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D015106:3',5'-Cyclic-GMP Phosphodiesterases