Epstein-Barr virus associated posttransplant malignant lymphoma in renal allograft recipients.
We report two cases of posttransplant malignant lymphoma(PTML) of B cell origin associated with Epstein-Barr virus(EBV) infection. They were a 52-year-old male and a 37 year-old-female, in whom intermediate-grade diffuse malignant lymphomas of large cell type developed in the submandibular area and jejunum, respectively. DNA and RNA in situ hybridization revealed the presence of EBV-specific DNA and RNA sequences in the tumor cells.
Choi
Y J
YJ
Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea.
Kang
C S
CS
Shin
W S
WS
Jee
M K
MK
Kim
B K
BK
Kim
S M
SM
Shim
S I
SI
D000328:Adult; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D017403:In Situ Hybridization; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000473:pathology; D008223:Lymphoma / Q000150:complications* / Q000473:pathology / Q000821:virology; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous; D014412:Tumor Virus Infections / Q000150:complications*