title: Propofol and methohexitone anaesthesia: effects on the profile of mood state.
abstract: The influence on mood of anaesthesia by infusion with propofol or methohexitone was evaluated in 80 female patients assessed with the Profile of Mood State preoperatively and at 30 min, 1, 2 and 4 h after anaesthesia. Patients given propofol were more elated and continuously less anxious than those given methohexitone from 1 to 4 h after anaesthesia (54.3, SEM 1.1 vs. 50.7 SEM 1.2). They also felt more agreeable after 2 h (45.4 SEM 1.4 vs. 48.4 SEM 1.2). All patients felt more tired and more confused post-operatively than pre-operatively. Propofol has different and more favourable influences on the post-operative mood state than does methohexitone.
authors.affiliation: Department of Anaesthesiology, Flemish Free University of Brussels Medical Center, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: D'Haese
authors.forename: F
authors.initials: F
authors.lastname: Camu
authors.forename: P J
authors.initials: PJ
authors.lastname: Dekeyzer
authors.forename: H A
authors.initials: HA
authors.lastname: D'Haenen
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects*; D000556:Ambulatory Surgical Procedures; D000771:Anesthesia, Intravenous; D001007:Anxiety / Q000523:psychology; D001290:Attitude; D003071:Cognition / Q000187:drug effects; D003221:Confusion / Q000503:physiopathology; D003863:Depression / Q000523:psychology; D004644:Emotions / Q000187:drug effects; D005221:Fatigue / Q000503:physiopathology; D005260:Female; D006791:Hostility; D006801:Humans; D008723:Methohexital / Q000494:pharmacology*; D010555:Personality Inventory; D015742:Propofol / Q000494:pharmacology*; D011446:Prospective Studies
chemical_list: D008723:Methohexital; D015742:Propofol