title: Syndrome of continuous muscle fiber activity. Case report with 11-year follow-up.
abstract: A 16-year-old male patient who presented with muscle stiffness and dysphonia is described. Electromyography revealed continuous motor activity that was unaffected by peripheral nerve block or general anaesthesia, but was abolished by curare. The patient had a marked improvement after using phenytoin. The follow-up 11-years later corroborates with the proposed benignity of this syndrome, in spite of being dependent on medication.
authors.affiliation: Neurology Service, Hospital of Clinics, Federal University of Minas Gerais, Medical School, Belo Horizonte, Brasil.
authors.forename: J T
authors.initials: JT
authors.lastname: de Oliveira
authors.forename: I
authors.initials: I
authors.lastname: Levy-Reis
mesh_terms: D000293:Adolescent; D004576:Electromyography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000502:physiology; D009127:Muscle Rigidity / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D009132:Muscles / Q000187:drug effects / Q000503:physiopathology*; D010672:Phenytoin / Q000627:therapeutic use; D016750:Stiff-Person Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D014832:Voice Disorders / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology
chemical_list: D010672:Phenytoin