title: A case of primary gastric choriocarcinoma and a review of the Japanese literature.
abstract: A 63-year old woman who had experienced melena for 2 weeks was admitted to Tokyo University Hospital. Gastric adenocarcinoma was diagnosed endoscopically and histologically, and a total gastrectomy was performed soon thereafter. Pathological examination of the resected stomach revealed choriocarcinoma of the stomach. Although chemotherapy was administered after surgery, she died 3 months after admission. Autopsy confirmed the diagnosis of primary gastric choriocarcinoma, a rare, but highly malignant tumor. It is characteristic; macroscopically it forms a necrotic mass with bleeding, and microscopically it often consists of adenocarcinoma and choriocarcinoma. Since its prognosis is extremely poor, we must take into account the possibility of primary gastric choriocarcinoma when a hemorrhagic gastric tumor with necrosis is found.
authors.affiliation: Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Imai
authors.forename: T
authors.initials: T
authors.lastname: Kawabe
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Matsumura
authors.forename: Y
authors.initials: Y
authors.lastname: Komatsu
authors.forename: E
authors.initials: E
authors.lastname: Hamada
authors.forename: Y
authors.initials: Y
authors.lastname: Niwa
authors.forename: M
authors.initials: M
authors.lastname: Kurita
authors.forename: S
authors.initials: S
authors.lastname: Shiina
authors.forename: T
authors.initials: T
authors.lastname: Shimada
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002822:Choriocarcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology*