[The determination of the chemiluminescence of stimulated blood leukocytes in assessing the activity of chronic pyelonephritis].
The activity of oxidant metabolism was studied in leukocytes from the whole blood of 23 patients diagnosed to have urolithiasis, chronic pyelonephritis in remission. Leukocyte function was evaluated by registration of luminol-dependent chemiluminescence. Barium sulfate microcrystals served leukocyte stimulator. Chemiluminescence was registered by chemiluminometer NPA-02. Diagnostic implication of chemiluminescence and other clinical-laboratory parameters was derived from the equations of multiple linear regression arranged in a model. It is shown possible to significantly assess chronic inflammation activity in renal tissue by whole blood chemiluminescence and ESR. Low functional activity of neutrophils recorded by chemiluminescence may indicate chronicity of renal tissue inflammation.
Golovanov
S A
SA
Grishkova
N V
NV
Korystov
A S
AS
D002908:Chronic Disease; D006801:Humans; D007962:Leukocytes / Q000187:drug effects / Q000378:metabolism*; D016014:Linear Models; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology; D011704:Pyelonephritis / Q000097:blood* / Q000209:etiology; D014545:Urinary Calculi / Q000097:blood / Q000150:complications
D008165:Luminol
Opredelenie khemiliuminestsentsii stimulirovannykh leĭkotsitov krovi v otsenke aktivnosti khronicheskogo pielonefrita.