title: [Value of linsidomine (SIN 1) in the evaluation of myocardial viability by 201-Tl scintigraphy after exertion].
abstract: 201Tl scintigraphy can be used to determine exercise-induced ischemia and the viability of the hypoperfused myocardium as a function of radiotracer redistribution. Redistribution is calculated by differential analysis of the normalized circumferential curves of activity. Intravenous injection of linsidomine (SIN 1) a patent coronary vasodilatator, gives more reliable results than conventional imaging at the 4th h, and compares favourably with the results obtained at the 24th h after reinjection of 201 Tl. Linsidomine provides images in 60 to 90 min, in stable clinical conditions.
authors.affiliation: Clinique Cardiologique et Service de Cardiologie Nucléaire, CHU Necker-Enfants Malades, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Vacheron
authors.forename: P
authors.initials: P
authors.lastname: de Vernejoul
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005080:Exercise Test / Q000379:methods*; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D008981:Molsidomine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D017202:Myocardial Ischemia / Q000175:diagnosis; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes; D014665:Vasodilator Agents / Q000008:administration & dosage*
chemical_list: D013794:Thallium Radioisotopes; D014665:Vasodilator Agents; C002385:linsidomine; D008981:Molsidomine
vernacular_title: Intérêt de la linsidomine (SIN 1) pour l'évaluation de la viabilité myocardique par scintigraphie au 201Tl après effort.