Synthesis of new brassinosteroids with potential activity as antiecdysteroids.
The synthesis of four new brassinosteroids with 2 beta,3 beta-diol functionality and A/B cis and A/B trans ring junction is reported. These brassinosteroids could present activity as antiecdysteroids.
Brosa
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Department of Organic Chemistry, C.E.T.S. Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain.
Nusimovich
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S
Peracaula
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R
D000089:Acetic Anhydrides; D002778:Cholestanones / Q000138:chemical synthesis* / Q000494:pharmacology; D026461:Ecdysteroids; D005463:Fluoroacetates; D007447:Invertebrate Hormones / Q000037:antagonists & inhibitors*; D015394:Molecular Structure; D013237:Stereoisomerism; D013256:Steroids / Q000037:antagonists & inhibitors*; D013265:Stigmasterol / Q000737:chemistry
D000089:Acetic Anhydrides; D002778:Cholestanones; D026461:Ecdysteroids; D005463:Fluoroacetates; D007447:Invertebrate Hormones; D013256:Steroids; C017958:trifluoroacetic anhydride; C070164:homocastasterone; D013265:Stigmasterol