Cross-substitution of diazepam for barbital results in only a low incidence of audiogenic seizures upon withdrawal in dependent rats.
Reigel
C E
CE
Department of Pharmacology, Texas Tech University Health Sciences Center, Lubbock 79430.
Bourn
W M
WM
D000161:Acoustic Stimulation; D000818:Animals; D001462:Barbital / Q000009:adverse effects* / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012640:Seizures / Q000503:physiopathology*; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology*
D001462:Barbital; D003975:Diazepam