title: [Immune status dynamics in different lateralizations of focal traumatic brain lesions].
abstract: The changes occurring in the immunity of 118 patients with focal brain injuries verified at surgery and during computed tomography were studied in relation to hemispheric lateralization. Patients with left-sided brain injuries showed more severe abnormalities of immunity and had a considerable lot of pyoinflammatory complications, including extracerebral ones. In patients with right-sided brain injuries, compensation of the changed immune responses occurred more rapidly, but intracranial pyoinflammatory complications took place more frequently. The magnitude and changes in immunity were found to depend upon the hemispheric lateralization of focal brain injuries, which characterizes that the brain regions play unequal role in the formation of an immune response. Differences become significant at week 3 at the peak of secondary immunodeficiency.
authors.forename: V I
authors.initials: VI
authors.lastname: Gorbunov
authors.forename: I V
authors.initials: IV
authors.lastname: Gannushkina
authors.forename: L B
authors.initials: LB
authors.lastname: Likhterman
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D001924:Brain Concussion / Q000150:complications / Q000276:immunology; D001930:Brain Injuries / Q000150:complications / Q000276:immunology*; D002543:Cerebral Hemorrhage / Q000150:complications / Q000276:immunology; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006406:Hematoma / Q000150:complications / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D012887:Skull Fractures / Q000150:complications / Q000276:immunology; D013997:Time Factors
vernacular_title: Dinamika immunnogo statusa pri raznoĭ lateralizatsii travmaticheskikh ochagovykh porazheniĭ golovnogo mozga.