title: Simultaneous back-projection of AIDS incidence data for two or more groups.
abstract: Back-projection of AIDS incidence data is useful for estimating characteristics of the HIV epidemic curve and forms a basis for projections of the AIDS epidemic curve. Its application to subgroups of the population is limited by its imprecision for groups with a small number of cases. Back-projection can be made more precise by pooling data from different groups and linking their HIV infection intensities by a model. Here we propose a method based on proportional infection intensities and study its performance with simulations and applications to AIDS in different States of Australia and haemophiliacs in the U.S.A. This method of simultaneous back-projection is shown to reduce substantially the width of confidence intervals for HIV infection intensities and for total numbers infected.
authors.affiliation: Department of Statistics, LaTrobe University, Bundoora VIC, Australia.
authors.forename: I C
authors.initials: IC
authors.lastname: Marschner
authors.forename: S V
authors.initials: SV
authors.lastname: Newstead
authors.forename: N G
authors.initials: NG
authors.lastname: Becker
mesh_terms: D000465:Algorithms; D001315:Australia / Q000453:epidemiology; D016001:Confidence Intervals; D003627:Data Interpretation, Statistical; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission; D006467:Hemophilia A / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D016013:Likelihood Functions; D016015:Logistic Models; D018401:Sample Size; D015819:Substance Abuse, Intravenous / Q000453:epidemiology; D014481:United States / Q000453:epidemiology