title: Sero-diagnosis for viral hepatitis in 93 patients admitted with acute hepatitis in three different teaching hospitals in Lahore.
abstract: Serodiagnosis was done in 93 patients admitted with acute viral hepatitis (AVH) to three teaching hospitals in Lahore. Five (5.4%) had hepatitis A, 39 (41.9%) hepatitis B (2 of these were anti delta positive) [see erratum notice], 44 (47.3%) probable hepatitis E and 3(3.2%) had HAV/HBV co-infection. Antibody to hepatitis C (anti HCV) was detected in 6 patients (6.4%); 2 with HBV and 4 with probable HEV infection. Excluding 39 patients with hepatitis B and 3 with HBV as part of co-infection, there was evidence of previous HBV infection in 39 out of the remaining 51 patients. In the subset of 6 children, 3 had hepatitis A and 3 hepatitis E. Of these, 5 had evidence of previous exposure to HBV and one was also positive for anti HCV. Our results are suggestive of a strong background of HBV infection raising concern about its chronic sequelae in the community.
authors.affiliation: Department of Gastroenterology, Shaikh Zayed Hospital, Lahore.
authors.forename: Z
authors.initials: Z
authors.lastname: Haider
authors.forename: A A
authors.initials: AA
authors.lastname: Khan
authors.forename: K
authors.initials: K
authors.lastname: Rehman
authors.forename: M I
authors.initials: MI
authors.lastname: Janjua
authors.forename: J
authors.initials: J
authors.lastname: Iqbal
authors.forename: M A
authors.initials: MA
authors.lastname: Chishti
authors.forename: A
authors.initials: A
authors.lastname: Qayyum
authors.forename: S
authors.initials: S
authors.lastname: Hasnain
authors.forename: A
authors.initials: A
authors.lastname: Shahzad
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006506:Hepatitis A / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D006509:Hepatitis B / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D003699:Hepatitis D / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D016751:Hepatitis E / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D006525:Hepatitis, Viral, Human / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D006784:Hospitals, Teaching; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010154:Pakistan; D012424:Rural Population; D012698:Serologic Tests / Q000379:methods; D014505:Urban Population