title: Use of a gonadotropin releasing hormone agonist before vaginal surgery for cervical leiomyomas. A report of two cases.
abstract: Two cases of cervical myoma were treated with combined medical/surgical therapy using a gonadotropin releasing hormone agonist (GnRH-a) and transvaginal cervical myomectomy. Patients were treated with depot GnRH-a (leuprolide acetate) for two months followed by myomectomy. This approach allowed successful treatment with short hospitalization (< 24 hours). Potential benefits of this regimen include decreased intraoperative blood loss, outpatient management, decreased morbidity, decreased hospital expense and preservation of reproductive potential by avoiding hysterectomy.
authors.affiliation: Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, VA 23507.
authors.forename: J A
authors.initials: JA
authors.lastname: Sims
authors.forename: R
authors.initials: R
authors.lastname: Brzyski
authors.forename: K
authors.initials: K
authors.lastname: Hansen
authors.forename: C C
authors.initials: CC
authors.lastname: Coddington
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000601:surgery*; D007902:Length of Stay; D016729:Leuprolide / Q000627:therapeutic use*; D011300:Preoperative Care / Q000379:methods*; D016896:Treatment Outcome; D014463:Ultrasonography; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D003692:Delayed-Action Preparations; D016729:Leuprolide