title: [New antipsychotic agents].
abstract: In the eighties, the notions of refractory schizophrenia and of atypical neuroleptics have been described. An "atypical" neuroleptic is an effective antipsychotic drug without inducing concomitant extrapyramidal side effects. The concept of atypicity has become a new vista for research of new antipsychotic drugs. The notions of partial dopaminergic agonism, antagonism of D4 receptor, selective 5HT2 antagonism must be viewed as a source of future research and therapeutic improvement.
authors.affiliation: Clinique et département de psychiatrie, CHU Robert-Debré, Reims.
authors.forename: T
authors.initials: T
authors.lastname: Brochier
mesh_terms: D014150:Antipsychotic Agents / Q000145:classification / Q000494:pharmacology; D018492:Dopamine Antagonists / Q000627:therapeutic use; D006801:Humans; D012106:Research; D012559:Schizophrenia / Q000188:drug therapy
chemical_list: D014150:Antipsychotic Agents; D018492:Dopamine Antagonists
vernacular_title: Les nouveaux antipsychotiques.