[Inhibition of aldose reductase by Chinese herbal medicine].
Seven Chinese herbal drugs were screened for experimental inhibition of lens aldose reductase activity, among which quercetin exhibited potent enzyme-inhibitory activities in vitro. Its IC50 value was 3.44 x 10(-7) mol/L. It may be helpful in the prophylaxis and treatment of diabetic complications.
Mao
X M
XM
Nanjing Air Force Hospital.
Zhang
J Q
JQ
D000449:Aldehyde Reductase / Q000378:metabolism*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D007908:Lens, Crystalline / Q000201:enzymology*; D011794:Quercetin / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley
D004365:Drugs, Chinese Herbal; D011794:Quercetin; D000449:Aldehyde Reductase