Nitroethane poisoning from an artificial fingernail remover.
Confusion between acetone fingernail polish removers and artificial fingernail products containing acetonitrile and N,N-dimethyl-p-toluidine has resulted in pediatric morbidity and mortality. In the present case, a 20-month-old boy drank less than one ounce of Remove Artificial Nail Remover containing 100% nitroethane. In the emergency department he displayed cyanosis and 39% methemoglobinemia. Following intravenous methylene blue, the child's methemoglobin level dropped to 5.7% and he recovered uneventfully. Toxicity from nitroethane has not previously been reported in humans. Poison centers and emergency department personnel should be alert to another nail product which may be easily confused with acetone-containing nail polish removers.
Hornfeldt
C S
CS
Hennepin Regional Poison Center, Hennepin County Medical Center, Minneapolis, Minnesota 55415.
Rabe
W H
WH
D003358:Cosmetics / Q000009:adverse effects; D003490:Cyanosis / Q000139:chemically induced* / Q000188:drug therapy; D004630:Emergencies; D004980:Ethane / Q000031:analogs & derivatives* / Q000506:poisoning; D006801:Humans; D007223:Infant; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D008751:Methylene Blue / Q000627:therapeutic use; D009262:Nails; D009595:Nitroparaffins / Q000506:poisoning*; D011039:Poison Control Centers
D003358:Cosmetics; D009595:Nitroparaffins; C014705:nitroethane; D004980:Ethane; D008751:Methylene Blue