Mantel-Haenszel-type tests for testing equivalence or more than equivalence in comparative clinical trials.
This paper proposes Mantel-Haenszel-type statistics for testing whether a new treatment is at least as effective as the standard treatment in comparative binomial trials. The null hypotheses considered are of a specified nonzero difference and of a ratio not equal to unity. It is shown that we may also use these tests for testing the equivalence of two treatments.
Yanagawa
T
T
Department of Mathematics, Kyushu University, Fukuoka, Japan.
Tango
T
T
Hiejima
Y
Y
D001699:Biometry; D018849:Controlled Clinical Trials as Topic / Q000379:methods*; D006801:Humans; D015233:Models, Statistical