[Drugs and brief losses of consciousness in the elderly. Results of a case-control multicenter study].
To study the possible role of drugs intake in syncope in elderly patients, we conducted a multicentric case-control study in 588 cases and 1818 controls, controlling as an essential confounding variable the underlying cardiovascular diseases. The following class were in excess among the case: non tricyclic antidepressants (p < 0.0001, RR: 4.5), neuroleptic drugs (p < 0.05, RR: 1.8), and antiparkinsonian drugs (p < 0.02, RR: 2.7).
Cherin
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P
Service de Médecine Interne, Hôpital Salpétrière, Paris.
Colvez
A
A
De Periere
G D
GD
Sereni
D
D
D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006760:Hospitalization; D006801:Humans; D007049:Iatrogenic Disease / Q000453:epidemiology; D008297:Male; D013575:Syncope / Q000139:chemically induced* / Q000453:epidemiology
Médicaments et pertes brèves de connaissance chez les personnes âgées. Résultats d'une étude multicentrique cas contrôle. Le groupe Médicaments et PCB.