title: [Potential side-effects of oral contraception: hirsutism and hypertension].
abstract: Since we observed the development of hirsutism and hypertension in a series of middle-aged women using peroral contraceptive drugs, we tried to ascertain whether there is any correlation between body mass index, blood pressure and urinary elimination of a series of steroid hormones. Although most correlations tested were statistically insignificant, we found a statistically significant correlation between the systolic blood pressure and the sum of 11 beta-hydroxyandrosterone + oxoetiocholanolone + 11 beta-hydroxyetiocholanolone urinary excretion, as assessed by thin-layer chromatography of urinary 17-oxosteroids, using dansylhydrazine as a prelabelling reagent.
authors.affiliation: Ustav lékarské kosmetiky, Praha.
authors.forename: M
authors.initials: M
authors.lastname: Burdová
authors.forename: H
authors.initials: H
authors.lastname: Bĕlikovová
authors.forename: Z
authors.initials: Z
authors.lastname: Tomsová
mesh_terms: D000328:Adult; D000728:Androgens / Q000652:urine; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006628:Hirsutism / Q000139:chemically induced* / Q000652:urine; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*
chemical_list: D000728:Androgens; D003276:Contraceptives, Oral
vernacular_title: Potenciální vedlejsí úcinky perorální antikoncepce: hirzutismus a hypertenze.