Early infantile form of Krabbe disease with optic hypertrophy: serial MR examinations and autopsy correlation.
The development of white matter lesions in a case of autopsy-proved early infantile form of Krabbe disease was monitored by serial MR examinations. Hypertrophy of the optic nerves was present late in the course of the patient's disease and is a remarkable feature in this case.
Hittmair
K
K
MR Institute, University of Vienna, Austria.
Wimberger
D
D
Wiesbauer
P
P
Zehetmayer
M
M
Budka
H
H
D001284:Atrophy; D001344:Autopsy; D001921:Brain / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy; D007223:Infant; D007965:Leukodystrophy, Globoid Cell / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009900:Optic Nerve / Q000473:pathology*; D012189:Retrospective Studies