[Risk factors of cerebral toxoplasmosis in patients with HIV infection: data of a primary prevention trial].
To identify risk factors for cerebral toxoplasmosis (CT) in HIV patients (pts) with positive serology for Toxoplasma gondii and CD4 < 200/mm3, data from the placebo group (N = 280) of a primary prophylaxis trial, were analyzed. The probability of onset of CT (n = 46) was, at one year, 13.1%. Three baseline variables were independently associated with a higher risk of CT: group IV non AIDS, AIDS stage and CD4 < 50/mm3. Initial titer of antibodies to Toxoplasma gondii was not.
Pueyo
S
S
Inserm U330, Université de Bordeaux II.
Leport
C
C
Chene
G
G
Morlat
P
P
Hafner
R
R
Vilde
J L
JL
Luft
B
B
Salamon
R
R
Aubertin
J
J
D004311:Double-Blind Method; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006801:Humans; D011739:Pyrimethamine / Q000627:therapeutic use*; D012307:Risk Factors; D016781:Toxoplasmosis, Cerebral / Q000209:etiology / Q000517:prevention & control*
D011739:Pyrimethamine
Facteurs de risque de toxoplasmose cérébrale chez les patients infectés par le VIH: données d'un essai de prophylaxie primaire. Groupe d'étude ANRS 005/ACTG 154.