[Is male infertility caused by congenital bilateral atrophy of the vas deferens a clinical form of mucoviscidosis?].
We investigated clinical data, sweat electrolytes and cystic fibrosis (CF) mutations in twelve patients with congenital bilateral aplasia of vasa deferentia (CBAVD) to debate arguments for diagnosing CF. Sweat chloride concentration was definitely raised in four patients. Three patients are CF compound heterozygotes. Six patients are CF heterozygotes. This result reinforces the hypothesis that white males with CBAVD might have a mild form of CE.
Durieu
I
I
Centre Hospitalier Lyon Sud, Pierre Bénite.
Omar
F B
FB
Rollet
J
J
Durand
D V
DV
Morel
Y
Y
Gilly
R
R
Levrat
R
R
D001284:Atrophy; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000235:genetics; D008297:Male; D014649:Vas Deferens / Q000473:pathology*
La stérilité masculine par atrophie congénitale bilatérale des canaux déférents est-elle une forme clinique de mucoviscidose?