title: A comparison of a conventional non-ionic contrast medium (iohexol) alone and with adrenaline and an iso-osmolar non-ionic contrast medium (iotrolan) in computed tomographic arthrography of the shoulder.
abstract: The physico-chemical properties of the iso-osmolar dimeric contrast medium iotrolan offers potential advantages in computed tomographic arthrography (CTA). A trial was undertaken comparing iotrolan with iohexol to assess if these theoretical benefits produced an increase in the measured densities in a series of shoulder CTAs. The results showed that iotrolan did produce clinically useful increases in density when compared to a monomeric non-ionic contrast medium. The addition of adrenaline to the monomeric contrast medium produced a significant improvement in the computed tomography density which surpassed that offered by the dimeric contrast medium alone.
authors.affiliation: Department of Radiology, Royal Orthopaedic Hospital, Birmingham, UK.
authors.forename: R M
authors.initials: RM
authors.lastname: Wellings
authors.forename: A M
authors.initials: AM
authors.lastname: Davies
authors.forename: P B
authors.initials: PB
authors.lastname: Pynsent
authors.forename: V N
authors.initials: VN
authors.lastname: Cassar-Pullicino
mesh_terms: D001175:Arthrography / Q000379:methods*; D003287:Contrast Media; D004837:Epinephrine; D006801:Humans; D007472:Iohexol; D017006:Rotator Cuff / Q000000981:diagnostic imaging; D000070636:Rotator Cuff Injuries; D012785:Shoulder Joint / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods; D014283:Triiodobenzoic Acids
chemical_list: D003287:Contrast Media; D014283:Triiodobenzoic Acids; C033300:iotrolan; D007472:Iohexol; D004837:Epinephrine