Highly attenuated poxviruses induce functional priming of neutrophils in vitro.
Highly attenuated poxvirus samples were used to examine the influence of potential poxvirus expression vector systems on neutrophil function. Exposure to the viruses alters the number of membrane bound complement-and Fc gamma-receptors and led to functional priming of neutrophils to subsequent stimuli.
Förster
R
R
Institut für Medizinische Mikrobiologie, Infektions- und Seuchenmedizin, Ludwig-Maximilian-Universität München, Federal Republic of Germany.
Wolf
G
G
Mayr
A
A
D000818:Animals; D002417:Cattle; D002460:Cell Line; D002642:Chick Embryo; D005822:Genetic Vectors; D006801:Humans; D009504:Neutrophils / Q000276:immunology* / Q000382:microbiology; D011212:Poxviridae / Q000235:genetics / Q000276:immunology*; D011951:Receptors, Complement / Q000378:metabolism; D017452:Receptors, IgG / Q000378:metabolism; D012756:Sheep; D014613:Vaccines, Attenuated / Q000276:immunology
D011951:Receptors, Complement; D017452:Receptors, IgG; D014613:Vaccines, Attenuated