title: [Clinical evaluation of fluoxetine].
abstract: The multicenter trials were performed in a group of 86 depressive inpatients (among them 64 with endogenous depression) managed with fluoxetine (Prozac). It was established that the drug is most effective in managing psychogenic depressions and may also be of use in endogenous depressions, among them in drug resistant ones. Tolerance to the drug was satisfactory, 62% did not show any unwanted side-effects. The rest of the group displayed sleep disorders, increased anxiety, lost of appetite and nausea. Changes in the laboratory parameters and non-specific changes in the electrocardiogram were observed sporadically. Fluoxetine seemed not to have any direct cholinolytic effect.
authors.affiliation: II Kliniki Psychiatrycznej, Instytutu Psychiatrii i Neurologii w Warszawie.
authors.forename: S
authors.initials: S
authors.lastname: Puzyński
authors.forename: J
authors.initials: J
authors.lastname: Rybakowski
authors.forename: J
authors.initials: J
authors.lastname: Kocur
authors.forename: Z
authors.initials: Z
authors.lastname: Rydzyński
authors.forename: M
authors.initials: M
authors.lastname: Beresewicz
authors.forename: E
authors.initials: E
authors.lastname: Bogdanowicz
authors.forename: S
authors.initials: S
authors.lastname: Duszyk
authors.forename: W
authors.initials: W
authors.lastname: Gruszczyński
authors.forename: A
authors.initials: A
authors.lastname: Kalinowski
authors.forename: I
authors.initials: I
authors.lastname: Koszewska
mesh_terms: D003866:Depressive Disorder / Q000188:drug therapy*; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D005473:Fluoxetine
vernacular_title: Ocena kliniczna fluoksetyny (wyniki badań wieloośrodkowych).