The sole DNA damage induced by bromodeoxyuridine is sufficient for initiation of both aging and carcinogenesis in vivo.
Anisimov
V N
VN
Laboratory of Experimental Tumors, N. N. Petrov Research Institute of Oncology, St. Petersburg, Russia.
D000375:Aging / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D001973:Bromodeoxyuridine / Q000633:toxicity*; D004249:DNA Damage / Q000502:physiology; D005260:Female; D008136:Longevity / Q000187:drug effects; D008297:Male; D051379:Mice; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000503:physiopathology; D051381:Rats; D012098:Reproduction / Q000187:drug effects
D001973:Bromodeoxyuridine