[Activity of free radical lipid oxidation and the state of antioxidant system in patients with ischemic heart disease during myocardial revascularization].
It has been established that aortocoronary bypass surgery is characterized by imbalance in lipid peroxidation and antioxidant defense system. These changes are more pronounced in patients with the most severe forms of ischemic heart disease. During surgery the greatest intensity of lipid peroxidation is observed at the end of assisted circulation period. To prevent these disturbances it is necessary to minimize surgical trauma, reduce the duration of operation stages, refuse pronounced normobaric hyperoxia during cardiopulmonary bypass.
Dubikaĭtis
A Iu
AIu
Koniukhova
S G
SG
Kovalev
V A
VA
Vavilova
T V
TV
Shabunevich
L V
LV
Belotserkovskiĭ
M B
MB
D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000378:metabolism* / Q000601:surgery; D005112:Extracorporeal Circulation; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation; D008875:Middle Aged
D000975:Antioxidants; D005609:Free Radicals
Aktivnost' svobodnoradikal'nogo okisleniia lipidov i sostoianie antioksidantnoĭ sistemy u bol'nykh ishemicheskoĭ bolezn'iu serdtsa v khode operatsii revaskululiarizatsii miokarda.