[The clinical significance of detection of anti-PPD-IgG secreting cell, adenosine deaminase and anti-PPD-IgG antibody in pleural effusion].
Enzyme-Linked Immunospot Assay (ELISPOT) were designed in the diagnostic value of tuberculous pleurisy, had a sensitivity of 90% and specificity of 100%. Anti-PPD IgG antibodies detected by ELISA had a sensitivity of 45% and specificity of 86%. For ADA activity in pleural effesion, the sensitivity and specificity were 75%, 79% respectively. Comparing with ADA and ELISA methods, ELISPOT is a more useful method for diagnosis of tuberculosis pleurisy.
Zhou
Y J
YJ
Pulmonary department, Gu Lou hospital Nanjing.
Gao
Y Y
YY
D000243:Adenosine Deaminase / Q000032:analysis; D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis*; D000921:Antibody-Producing Cells / Q000276:immunology; D001426:Bacterial Proteins; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000276:immunology*; D010996:Pleural Effusion / Q000276:immunology / Q000378:metabolism*; D012680:Sensitivity and Specificity; D014373:Tuberculin / Q000276:immunology*; D014396:Tuberculosis, Pleural / Q000175:diagnosis*
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D007074:Immunoglobulin G; D010455:Peptides; D014373:Tuberculin; C009610:tuberculin-active protein, Mycobacterium; D000243:Adenosine Deaminase