[Relationship between T cell subsets and traditional Chinese medicine type in patient with ovarian tumor].
In order to study the difference in TCM types as well as between Deficiency and Excess type in immunity in the patients with ovarian tumors, the profile of peripheral blood T lymphocyte subsets in 73 cases of ovarian tumors was determined by using flow cytometry and monoclonal antibody technique. The results showed that the total T cells (OKT3) of peripheral blood were almost normal in 73 tumor cases. And 50 of them were malignant tumors in which T helper cell were progressively decreased and T suppressor cell gradually increased in accordance with the order of Qi-Deficiency, Yin-Deficiency, Qi-Yin Deficiency types. The T4/T8 ratio showed significant difference (P < 0.01) compared with the control group and the initial ovarian tumor group. These results indicated that the change in the T lymphocyte subset in tumor was correlated with TCM type and this serves as both clinically sensitive indexes of different TCM type and reflection of the patient's immunologic status.
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Shu-Guang Hospital, Shanghai College of TCM.
D000328:Adult; D016516:CD4-CD8 Ratio; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000276:immunology*; D016176:T-Lymphocyte Subsets; D016710:Yin Deficiency / Q000276:immunology