Desipramine for the treatment of "pure" dysthymia versus "double" depression.
The authors report results of an 8-week, open trial of desipramine in 42 patients with DSM-III-R dysthymia with a concurrent diagnosis of major depression ("double" depression) and 33 patients with dysthymia who had no other depressive diagnosis ("pure" dysthymia). Either complete or partial remission was achieved by 70% of the patients with "pure" dysthymia. This compared favorably with but was not significantly different from results in the "double" depression group.
Marin
D B
DB
Payne Whitney Clinic, Duke University Medical Center, Durham, N.C.
Kocsis
J H
JH
Frances
A J
AJ
Parides
M
M
D000328:Adult; D017668:Age of Onset; D000553:Ambulatory Care; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D003891:Desipramine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D010919:Placebos; D011569:Psychiatric Status Rating Scales; D016896:Treatment Outcome
D010919:Placebos; D003891:Desipramine