[Peroxide radicals in the metabolism of toxic substances].
The free radicals resulting from the metabolism of oxygen and some xenobiotics, can induce, when a limit concentration is exceeded, toxic effects due to their action on DNA, enzymes and fatty acids. Therefore, the association of oxygen therapy with drug administration may have a more or less beneficial effect. Thus, in a long-term treatment with drugs which by metabolized release free radicals, the use of exogenous compounds for protecting the human body need to be administered.
Proca
M
M
Disciplina de Toxicologie, Universitatea de Medicină şi Farmacie Iaşi.
Agoroaei
L
L
Butnaru
E
E
Cotrău
M
M
D005609:Free Radicals; D006801:Humans; D010084:Oxidation-Reduction; D010545:Peroxides / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism; D015262:Xenobiotics / Q000493:pharmacokinetics*
D005609:Free Radicals; D010545:Peroxides; D017382:Reactive Oxygen Species; D015262:Xenobiotics
Radicalii peroxidici în metabolizarea substanţelor toxice.