title: [Current aspects in diagnosis and therapy of pediatric facial paralysis].
abstract: Between 1986 and 1992, 60 children with facial nerve palsy (FNP) were examined at the ORL hospital at Erlangen-Nuremberg University. By using blood and cerebrospinal fluid (CSF)-serological tests acute infection with Borrelia burgdorferi (B.b.) could be proved in 16 of 40 children (40%) whose pareses could not be clarified etiologically at first examination. Whereas all idiopathic FNP patients (22) had normal CSF-results, more than half of the B.b.-infected children showed pathological findings, with pleocytosis indicating meningitis. These findings demonstrated that lumbar puncture should be performed in children with FNP of unclear etiology, particularly in cases with positive borreliosis blood serology. The children with borreliosis received penicillin G or ceftriaxone intravenously for at least 14 days and patients with idiopathic FNP were treated with cortisone either orally alone or intravenously in combination with pentoxifylline and hydroxyethylstarch. The outcome in 95% of the patients showed that complete recovery was similar in borreliosis and idiopathic FNP irrespective of treatment with cortisone. Overall, 88% of the FNP recovered completely, indicating a favorable prognosis of FNP in children.
authors.affiliation: Klinik und Poliklinik für Hals-, Nasen-, Ohrenkranke, Universität Erlangen-Nürnberg.
authors.forename: S R
authors.initials: SR
authors.lastname: Wolf
authors.forename: U
authors.initials: U
authors.lastname: Heininger
authors.forename: W
authors.initials: W
authors.lastname: Schneider
authors.forename: D
authors.initials: D
authors.lastname: Wenzel
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood; D015748:Borrelia burgdorferi Group / Q000276:immunology; D002443:Ceftriaxone / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003348:Cortisone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005158:Facial Paralysis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D008297:Male; D016920:Meningitis, Bacterial / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D010400:Penicillin G / Q000627:therapeutic use; D010431:Pentoxifylline / Q000627:therapeutic use
chemical_list: D000907:Antibodies, Bacterial; D002443:Ceftriaxone; D010400:Penicillin G; D010431:Pentoxifylline; D003348:Cortisone
vernacular_title: Aktuelle Aspekte in der Diagnostik und Therapie der kindlichen Fazialisparese.