title: Propafenone overdose.
abstract: Propafenone is an infrequently used class IC antiarrhythmic drug. We report our experience with a patient who overdosed with propafenone and developed coma, seizures, bradycardia, hypotension, and conduction delay. The clinical manifestations and management of this patient are discussed in light of the known pharmacology of propafenone and compared with the limited number of cases that appear in the literature.
authors.affiliation: Department of Emergency Medicine, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: W
authors.initials: W
authors.lastname: Kerns
authors.forename: B
authors.initials: B
authors.lastname: English
authors.forename: M
authors.initials: M
authors.lastname: Ford
mesh_terms: D000328:Adult; D001919:Bradycardia / Q000139:chemically induced; D062787:Drug Overdose; D004562:Electrocardiography / Q000187:drug effects; D006327:Heart Block / Q000139:chemically induced*; D006801:Humans; D008297:Male; D011405:Propafenone / Q000506:poisoning*; D012640:Seizures / Q000139:chemically induced
chemical_list: D011405:Propafenone