[Autoimmune biological anomalies in 35 patients with chronic viral hepatitis C treated over 6 months with interferon and followed-up over a year].
Several clinical or biological autoimmune disorders, particularly lupoid diseases, are associated with chronic hepatitis C. They may be exacerbated by alpha IFN, but they are not involved in the response to therapy.
Marcais
O
O
Service de médecine interne E, hôpital Saint-Eloi, Montpellier.
Hanslik
B
B
Coste
F
F
Perney
P
P
Clot
J
J
Blanc
F
F
D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology; D005260:Female; D005500:Follow-Up Studies; D006526:Hepatitis C / Q000150:complications* / Q000628:therapy; D006521:Hepatitis, Chronic / Q000150:complications* / Q000628:therapy; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged
D001323:Autoantibodies; D016898:Interferon-alpha
Anomalies biologiques autoimmunes chez 35 malades atteints d'hépatite chronique viral C traités pendant six mois par interféron (IFN) et suivis pendant un an.