title: [Cardiac complications of halofantrine: continuous electrocardiographic study (holter) in 20 patients].
abstract: Three cases of long QT-interval due to halofantrine were documented in 1992 in France. Two of them had a congenital long QT-interval (Romano-Ward syndrome). We performed a prospective study of cardiac monitoring in 20 patients taking halofantrine. Minimal ECG changes were noted with lengthening of the QT-interval. Systematic ECG is necessary before giving halofantrine.
authors.affiliation: Clinique médicale propédeutique, médecine interne et maladies tropicales, hôpital Saint André, CHU Bordeaux, France.
authors.forename: E
authors.initials: E
authors.lastname: Monlun
authors.forename: P
authors.initials: P
authors.lastname: Le Metayer
authors.forename: M C
authors.initials: MC
authors.lastname: Receveur
authors.forename: K
authors.initials: K
authors.lastname: Bouabdallah
authors.forename: D
authors.initials: D
authors.lastname: Neau
authors.forename: M
authors.initials: M
authors.lastname: Longy-Boursier
authors.forename: M
authors.initials: M
authors.lastname: Le Bras
mesh_terms: D000962:Antimalarials / Q000009:adverse effects*; D015716:Electrocardiography, Ambulatory; D006331:Heart Diseases / Q000139:chemically induced* / Q000517:prevention & control; D006801:Humans; D010616:Phenanthrenes / Q000009:adverse effects*; D011446:Prospective Studies
chemical_list: D000962:Antimalarials; D010616:Phenanthrenes; C023768:halofantrine
vernacular_title: Complications cardiaques de l'halofantrine: etude électrocardiographique continue (holter) chez 20 patients.