[Influence of evening primrose oil on blood pressure and the pressor response to angiotensin II in pregnant and non-pregnant rabbits].
Evening primrose oil was given through a intragastric catheter in dose of 50 mg/kg day for 10 days to pregnant (8 animals) and nonpregnant (8 animals) rabbits. Control groups contained 8 pregnant and 8 nonpregnant animals. In the acute experiment we estimated directly (intraarterially) basal blood pressure and pressor response to angiotensin II (A II). The systolic and diastolic response to A II was significantly lower in pregnant rabbits which received evening primrose oil compared to control group. No significant effect was found in the nonpregnant groups. Basal (before A II) systolic and diastolic blood pressure did not differ between the treated and untreated subject in each group.
Zieliński
M
M
Kliniki Patologii Ciazy i Porodu IPG PAM w Szczecinie.
Wojnarski
L
L
Celewicz
Z
Z
Cretti
A
A
D000804:Angiotensin II; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D005260:Female; D010938:Plant Oils / Q000494:pharmacology*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects* / Q000502:physiology; D011817:Rabbits
D010938:Plant Oils; D000804:Angiotensin II
Wpływ oleju z nasion wiesiołka na ciśnienie tetnicze krwi i na reakcje presyjna na angiotensyne II u ciezarnych i nieciezarnych królic.