title: A fulminant case of neuroleptic malignant syndrome.
abstract: We report a fulminant case of Neuroleptic Malignant Syndrome in a 31-year-old male schizophrenic on haloperidol, thioridazine, benzhexol and flurazepam who presented with rigidity, fever, stupor and autonomic instability. He succumbed rapidly over 6 days to rhabdomyolysis, acute renal failure, status epilepticus and disseminated intravascular coagulopathy despite treatment with dantrolene and bromocriptine at the outset.
authors.affiliation: Department of Geriatric Medicine, Tan Tock Seng Hospital, Singapore.
authors.forename: S K
authors.initials: SK
authors.lastname: Teo
authors.forename: K N
authors.initials: KN
authors.lastname: Lam
authors.forename: W L
authors.initials: WL
authors.lastname: Chew
mesh_terms: D000328:Adult; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D006220:Haloperidol / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000150:complications / Q000175:diagnosis*; D009460:Neurologic Examination / Q000187:drug effects; D012559:Schizophrenia / Q000188:drug therapy*; D013881:Thioridazine / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D006220:Haloperidol; D013881:Thioridazine