title: [The clinico-tomographic correlates in Alzheimer's disease].
abstract: Brain computed tomographic scans of 43 patients with Alzheimer's disease (moderate and severe dementia) were compared to those of age-matched normal subjects (30 controls). Computed tomographic analysis included some linear and volume ventricular measurements. These indices correlated with relevant psychopathological and psychometric findings. Linear measurements of the ventricular size and the degree of cortical, central atrophy were significantly greater in patients with Alzheimer's disease than in the control group. In line with the disease progression and its development from moderate to severe dementia the degree of brain structural changes increased with the predominance of cortical atrophy in parietal lobes and central atrophy in mediobasal parts of the temporal lobes.
authors.forename: N D
authors.initials: ND
authors.lastname: Selezneva
authors.forename: I V
authors.initials: IV
authors.lastname: Kolykhanov
authors.forename: N M
authors.initials: NM
authors.lastname: Nikiforuk
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Savvateva
authors.forename: E N
authors.initials: EN
authors.lastname: Ermilova
authors.forename: S B
authors.initials: SB
authors.lastname: Vavilov
authors.forename: S I
authors.initials: SI
authors.lastname: Gavrilova
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000000981:diagnostic imaging* / Q000523:psychology; D001284:Atrophy / Q000000981:diagnostic imaging / Q000523:psychology; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009484:Neuropsychology; D014057:Tomography, X-Ray Computed
vernacular_title: Kliniko-tomograficheskie korreliatsii pri bolezni Al'tsgeĭmera.