Physical mapping in the region of the Bruton's tyrosine kinase and alpha-galactosidase A gene loci in proximal Xq22.
We have produced physical maps of the proximal part of Xq22, containing the Bruton's tyrosine kinase (BTK) and alpha-galactosidase A (GLA) gene loci, using long range physical mapping techniques and yeast artificial chromosomes (YACs). These maps reveal five previously unidentified CpG islands which could indicate the presence of other genes in this region.
Sweatman
A K
AK
Molecular Immunology Unit, University of London, UK.
Bradley
L A
LA
Lovering
R C
RC
O'Reilly
M A
MA
Levinsky
R J
RJ
Kinnon
C
C
D000077329:Agammaglobulinaemia Tyrosine Kinase; D001483:Base Sequence; D002874:Chromosome Mapping; D008040:Genetic Linkage; D006801:Humans; D008969:Molecular Sequence Data; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D015183:Restriction Mapping; D014960:X Chromosome; D000519:alpha-Galactosidase / Q000235:genetics*
D011505:Protein-Tyrosine Kinases; D000077329:Agammaglobulinaemia Tyrosine Kinase; C000625949:BTK protein, human; D000519:alpha-Galactosidase