title: Wavelength index: a predictor of the response to disopyramide in paroxysmal lone atrial fibrillation.
abstract: We investigated whether the new parameter wavelength index could predict the response to chronic disopyramide therapy in patients with paroxysmal atrial fibrillation (AF). Twenty-seven patients with AF underwent electrophysiologic studies and the wavelength index was determined before and after intravenous administration of disopyramide. Then all patients were treated with oral disopyramide for 6 months. In 17 patients, AF was eliminated (group A), while it persisted in another 10 patients (group B). The ratio of the wavelength index before and after intravenous disopyramide was higher in group A than in group B. Thus, the wavelength index proved useful for predicting the response of AF to disopyramide.
authors.affiliation: Department of Internal Medicine, School of Medicine, Fukuoka University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kumagai
authors.forename: N
authors.initials: N
authors.lastname: Gondo
authors.forename: K
authors.initials: K
authors.lastname: Matsuo
authors.forename: M
authors.initials: M
authors.lastname: Annoura
authors.forename: K
authors.initials: K
authors.lastname: Moroe
authors.forename: Y
authors.initials: Y
authors.lastname: Nakashima
authors.forename: T
authors.initials: T
authors.lastname: Hiroki
authors.forename: K
authors.initials: K
authors.lastname: Arakawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000188:drug therapy* / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial; D004206:Disopyramide / Q000627:therapeutic use*; D004562:Electrocardiography; D006801:Humans; D008875:Middle Aged
chemical_list: D004206:Disopyramide