Engineering of antibodies for breast cancer therapy: construction of chimeric and humanized versions of the murine monoclonal antibody BrE-3.
Couto
J R
JR
Cancer Research Fund of Contra Costa, Walnut Creek, California 94596.
Blank
E W
EW
Peterson
J A
JA
Kiwan
R
R
Padlan
E A
EA
Ceriani
R L
RL
D000595:Amino Acid Sequence; D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry* / Q000276:immunology / Q000627:therapeutic use; D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm / Q000276:immunology*; D001483:Base Sequence; D001943:Breast Neoplasms / Q000276:immunology* / Q000628:therapy; D003001:Cloning, Molecular; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007145:Immunoglobulin kappa-Chains / Q000276:immunology; D007167:Immunotherapy; D008562:Membrane Glycoproteins / Q000276:immunology*; D051379:Mice; D018598:Minisatellite Repeats; D008969:Molecular Sequence Data; D018396:Mucin-1; D009077:Mucins / Q000276:immunology*; D009363:Neoplasm Proteins / Q000276:immunology; D015202:Protein Engineering; D011993:Recombinant Fusion Proteins / Q000737:chemistry* / Q000276:immunology / Q000627:therapeutic use
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D008562:Membrane Glycoproteins; D018396:Mucin-1; D009077:Mucins; D009363:Neoplasm Proteins; D011993:Recombinant Fusion Proteins