title: [Incidence and treatment of vascular prosthesis infection in the groin. Personal experience].
abstract: The incidence of prosthesis infection in the groin ranges between 1 and 3%, with high morbidity and mortality rates. Contamination, irrespective of whether it is endogenous or exogenous, may occur during surgery of afterwards due to a secondary bacterial load which is often associated with a traumatic surgical technique for tissues, often in emergency surgery or re-operations. MATERIALS AND METHODS. Over the past 5 years a total of 410 prosthetic alloplastic grafts have been made by our Division of Vascular Surgery with at least one anastomosis at an inguinal level. The materials used for prosthesis were dacron and PTFE. Thirty-one infections were observed in the groin of which 11 involved the prosthesis and 20 were apparently restricted to the superficial and deep layer of the dermis. A cell culture test and antibiogram was always performed. Surgical or medical therapy (loco-regional + general) was used according to individual cases. RESULTS. With regard to the 11 patients with manifest infections of the prosthesis, only trans-obturator bypass surgery gave positive long-term results, whereas other operations (femoro-femoral bypass, axillo-popliteal bypass) were not satisfactory. Of the other 20 patients treated using loco-regional and general medical therapy, 9 developed pseudo aneurysm over time for which it was then necessary to resort to surgery. DISCUSSION AND CONCLUSION. Currently there is no universally accepted treatment protocol for the management of prosthesis infection. However, it is generally considered useful to isolate any pathological agent (using routine biopsies of arterial wall or thrombo-endoluminal fragments during the primary operation) before infection can develop so as to be able to commence specific antibiotic therapy. In this context the authors underline the more devastating action of some bacteria (pseudomonas, Staphylococcus aureus) in comparison to others (Staphylococcus epidermidis). Turning to therapeutic measures, when there are anatomical grounds and with the greatest possible respect for periarterial tissues, it is considered that trans-obturator bypass is preferable in the presence of manifest infection of the prosthesis, whereas medical therapy can be used (loco-regional + general) if infection is limited to the surface layers of the inguinal area. Possible complications over time may be corrected using surgery and in situ reconstruction if infection is no longer present.
authors.affiliation: Divisione di Chirurgia Vascolare, Ospedale Santa Corona, Pietra Ligure, Savona.
authors.forename: U
authors.initials: U
authors.lastname: Bonelli
authors.forename: R
authors.initials: R
authors.lastname: Cerruti
authors.forename: F
authors.initials: F
authors.lastname: Baglietto
authors.forename: C
authors.initials: C
authors.lastname: Cantello
authors.forename: N
authors.initials: N
authors.lastname: Zinicola
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D002177:Candidiasis / Q000209:etiology; D004630:Emergencies; D005260:Female; D006119:Groin; D006801:Humans; D007239:Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene; D012086:Reoperation
chemical_list: D000900:Anti-Bacterial Agents; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene
vernacular_title: Incidenza e trattamento della infezione protesica vascolare a livello inguinale. Esperienza personale.