Gasoline vapors induce severe rhabdomyolysis.
A young patient developed rhabdomyolysis after accidentally inhaling gasoline vapors. Although there had been no preexistent myopathy, the caffeine and halothane contracture test classified the patient as being malignant hyperthermia-susceptible (MHS). Abnormal contractures also occurred after exposure of muscle bundles to benzine (at 0.01%); in four control tests, benzine-induced contractures (at 0.1%) could be elicited in MHS, but not in normal, muscles. The complex composition of benzine seems to contain potentially hazardous agents that trigger MH.
Anetseder
M
M
Department of Anesthesiology, University Wuerzburg, Germany.
Hartung
E
E
Klepper
S
S
Reichmann
H
H
D000328:Adult; D000428:Alcohol Drinking; D001334:Automobile Driving; D002110:Caffeine; D003402:Creatine Kinase / Q000097:blood; D005742:Gasoline / Q000009:adverse effects*; D006221:Halothane; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000503:physiopathology*; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000175:diagnosis
D005742:Gasoline; D002110:Caffeine; D003402:Creatine Kinase; D006221:Halothane