title: Curative endocavitary irradiation of small rectal cancers and preoperative radiotherapy in T2 T3 (T4) rectal cancer. A brief overview of the Lyon experience.
abstract: The aim of this study was the analysis of 414 patients treated by endocavitary irradiation for small T1 (T2) infiltrating adenocarcinomas between 1951-93 and of 337 patients treated by preoperative radiotherapy for T2 T3 (T4) rectal cancer, between 1978-92. Endocavitary irradiation was delivered with Papillon's technique using the PHILLIPS RT-50 machine. Preoperative external beam radiotherapy was given to the posterior pelvis only with an accelerated schedule of 39 Gy in 13 fractions over 18 days. Endocavitary irradiation with the use of intra-rectal ultrasound for patient selection resulted in a local control rate of 91% with no complication even in the medically inoperable patients. Preoperative external beam radiotherapy followed by radical resection resulted in a 90% pelvic control rate. Sphincter-sparing surgery was possible in 60% of patients with low or middle rectal lesions.
authors.affiliation: Service de Radiothérapie-Oncologie, Centre Hospitalier Lyon Sud, Pierre Benite, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Gerard
authors.forename: R
authors.initials: R
authors.lastname: Coquard
authors.forename: D
authors.initials: D
authors.lastname: Fric
authors.forename: L
authors.initials: L
authors.lastname: Ayzac
authors.forename: P
authors.initials: P
authors.lastname: Romestaing
authors.forename: J M
authors.initials: JM
authors.lastname: Ardiet
authors.forename: F P
authors.initials: FP
authors.lastname: Rocher
authors.forename: M H
authors.initials: MH
authors.lastname: Baron
authors.forename: V
authors.initials: V
authors.lastname: Trillet-Lenoir
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D000368:Aged; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome