[Alteration of human leukocyte antigens in human parathyroid tissues after transplantation into nude mice].
Human parathyroid (PTG) tissues from cadaver (C-PTG), 20-28 wk fetus (F-PTG) and PTG adenoma (A-PTG) were transplanted into the kidney subcapsular spaces of Balb/C nude mice as interim host. Dynamic changes in the amount of human leukocyte antigens (HLA) in human PTG grafts within the transplantation period were observed. The results showed that during 100 days of interim hosting, no obvious changes in the amount of tissue HLA class I antigens occurred, but the amount of tissue HLA class II antigens were significantly reduced, The changes of HLA antigens in the different types of donor human PTG tissues were compared.
Gao
Z
Z
PUMC Hospital, CAMS, Beijing.
Zhu
Y
Y
D000236:Adenoma / Q000276:immunology; D000818:Animals; D016332:Fetal Tissue Transplantation; D006680:HLA Antigens / Q000378:metabolism*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D010280:Parathyroid Glands / Q000276:immunology* / Q000637:transplantation; D010282:Parathyroid Neoplasms / Q000276:immunology; D013370:Subrenal Capsule Assay
D006680:HLA Antigens