title: Decreased erythrocyte osmotic fragility during canine leptospirosis.
abstract: Erythrocyte osmotic fragility (EOF) was carried out in nineteen dogs naturally infected by Leptospira interrogans serovar icterohaemorrhagiae/copenhagi. A decreased EOF was observed, suggesting a modification of erythrocyte components secondary to disturbances that occur during canine leptospirosis, such as renal damage and hepatic disease.
authors.affiliation: Laboratory of Pathophysiology-Institute Butantan, São Paulo, Brazil.
authors.forename: M L
authors.initials: ML
authors.lastname: Santoro
authors.forename: M M
authors.initials: MM
authors.lastname: Kogika
authors.forename: M K
authors.initials: MK
authors.lastname: Hagiwara
authors.forename: R M
authors.initials: RM
authors.lastname: Mirandola
authors.forename: I L
authors.initials: IL
authors.lastname: Castelar
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000097:blood / Q000382:microbiology* / Q000503:physiopathology; D004285:Dogs; D006461:Hemolysis; D007921:Leptospira interrogans; D009996:Osmotic Fragility / Q000502:physiology*; D014895:Weil Disease / Q000097:blood / Q000662:veterinary*