Urinary methamphetamine concentration following famprofazone administration.
A 37-year-old man had a considerable concentration of methamphetamine in his urine, but he denied taking any abused drug. It was found that he took a pain killer that contains famprofazone, a relatively strong analgesic whose metabolites include methamphetamine and amphetamine. The human urinary metabolism of famprofazone was investigated. Immunoassay was used as a preliminary test, and gas chromatography with flame-ionization detection and gas chromatography-mass spectrometry were used for quantitation and confirmation.
Yoo
Y
Y
National Institute of Scientific Investigation, Seoul, Korea.
Chung
H
H
Choi
H
H
D000328:Adult; D000661:Amphetamine / Q000652:urine; D001711:Biotransformation; D002849:Chromatography, Gas; D017248:Enzyme Multiplied Immunoassay Technique; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008694:Methamphetamine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000378:metabolism / Q000652:urine*; D011720:Pyrazoles / Q000008:administration & dosage / Q000378:metabolism*; D047069:Pyrazolones
D011720:Pyrazoles; D047069:Pyrazolones; D008694:Methamphetamine; D000661:Amphetamine; C076013:famprofazone