Interocular transfer in the split-brain rat.
After the 1991 development of a method to transect the optic chiasm in the rat, the authors investigated interocular transfer in split-chiasm rats with corpus callosum section and callosum intact. Rats were monocularly trained on an orientation discrimination, reversed with the other eye, and retrained with the 1st eye on the 2nd-eye problem or reversal. In split-chiasm rats, the 2nd-eye S+ (correct stimulus) showed strong transfer (55% savings) to the 1st eye. S- (incorrect stimulus) did not; reversal and transfer groups differed significantly. Split-brain rats retrained with the 1st eye on the 2nd eye S+ required no more trials than original learning, as if they had not experienced this problem. Split-brain rats retested with the original S+ showed modest (19%) savings. The findings establish interhemispheric communication via the callosum and suggest, as in findings of cat and monkey studies, the disruption of transfer by callosal section.
Crowne
D P
DP
Department of Psychology, University of Waterloo, Ontario, Canada.
Forsyth
P
P
Fitzgerald
J
J
D000818:Animals; D001070:Appetitive Behavior / Q000502:physiology; D001362:Avoidance Learning / Q000502:physiology; D001931:Brain Mapping; D003337:Corpus Callosum / Q000502:physiology*; D004193:Discrimination Learning / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology*; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D009897:Optic Chiasm / Q000502:physiology*; D009949:Orientation / Q000502:physiology*; D051381:Rats; D012160:Retina / Q000502:physiology*; D012193:Reversal Learning / Q000502:physiology; D014163:Transfer, Psychology; D014795:Visual Pathways / Q000502:physiology