[Dynamics of digoxin-like immunoactivity during the oral glucose tolerance test in pregnant women].
The changes of serum digoxin-like immunoactivity (DLIA) during 75g oral glucose tolerance test (OGTT), were investigated in 25 pregnant women with various glucose tolerance. 13 women had a normal glucose tolerance (NGT), 12 women had an impaired glucose tolerance (IGT) or gestational diabetes mellitus (GDM). Test was performed after 25 week of pregnancy. The results were compared with 9 nonpregnant healthy volunteers (NHV). After an oral glucose challenge, there was observed a significant decrease in serum DLIA (p < 0.01 in 1st hour), in both groups of the pregnant women. In the group of NHV these findings were not found. Our findings suggest a possible relationships between DLIA and glucose tolerance in pregnant women. However, it needs further investigation. (Tab. 1, Fig. 1, Ref. 24.)
Martinka
E
E
Jeseniova lekárska fakulta Univerzity Komenského v Martine, I. interná klinika MFN, Martin, Slovakia.
Matúsek
J
J
Mokán
M
M
Ochodnický
M
M
Kvĕtenský
J
J
Danko
J
J
Stasko
J
J
Vladár
L
L
D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D002298:Cardenolides; D016640:Diabetes, Gestational / Q000097:blood; D004077:Digoxin; D005260:Female; D018149:Glucose Intolerance / Q000097:blood; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy / Q000097:blood*; D011248:Pregnancy Complications / Q000097:blood; D012503:Saponins; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors*
D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin; D000254:Sodium-Potassium-Exchanging ATPase
Dynamika digoxínu podobnej imunoaktivity pocas OGTT u tehotných zien.