title: [Quantitative analysis of gallbladder function using quantitative dynamic radionuclide cholecystography].
abstract: The aim of the study is to demonstrate general function of the cholecyst through selected quantitative parameters derived from the quantitative radionuclide cholecystography method, using our own computer software HIDATA, and to evaluate values of specific quantitative parameters in 15 patients presenting with chronic calculous and 15 with chronic acalculous cholecystitis. A control group comprised 10 subjects with no changes on the cholecyst. Of four quantitative parameters calculated during cholecyst filling, the only significant one was the ascending segment slope of the curve from specific ROI, that is, K1 derived from it, because it shows its functional status, depending on the changes in its wall and the lumen content. The most significant parameters which maintain motor function of the cholecyst are ejection fraction (EF) and ejection rate (ER) which are always decreased in chronic cholecystitis, regardless of the presence of calculosis and the number of calculi in the lumen. The ejection fraction is especially decreased in the multiple sclerosis group; it is significantly decreased when compared with acalculous chronic cholecystitis. Our results indicate that a selection of parameters used in clinical practice for the assessment of the cholecyst function is necessary. Our program HIDATA included a large number of parameters of which three were classified as important for the assessment of the cholecyst function (K1, EF, ER), reflecting the process of filling and emptying of the cholecyst and offering reliable and valuable data for the treatment.
authors.affiliation: Sluzba za nuklearnu medicinu, Hirurska klinika, Medicinski fakultet i KBC Kragujevac.
authors.forename: M
authors.initials: M
authors.lastname: Matović
authors.forename: K
authors.initials: K
authors.lastname: Kostić
authors.forename: B
authors.initials: B
authors.lastname: Novaković
authors.forename: S
authors.initials: S
authors.lastname: Alempijević
authors.forename: L
authors.initials: L
authors.lastname: Mijatović
authors.forename: B
authors.initials: B
authors.lastname: Jeremić
mesh_terms: D002764:Cholecystitis / Q000000981:diagnostic imaging / Q000503:physiopathology; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000503:physiopathology; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007091:Image Processing, Computer-Assisted; D011877:Radionuclide Imaging
vernacular_title: Kvantitativna analiza funkcije holeciste metodom kvantitativne dinamicke radionuklidne holecistografije.