[Hairy-cell leukemia (a review of the literature and the authors' own data)].
Gene engineering interferon made in Russia (reaferon, realdiron) was given to 40 patients with hairy-cell leukemia. Complete and partial remissions were achieved in 56% and 28% of the patients, respectively. Minimum effect was reported in 3% of the cases. In 5 cases with primary resistance or recurrences the authors used pentostatin which produced complete remissions in all the five patients.
Volkova
M A
MA
Lepkov
S V
SV
Frenkel'
M A
MA
Lebedeva
N B
NB
Tupitsyn
N N
NN
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007943:Leukemia, Hairy Cell / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015649:Pentostatin / Q000627:therapeutic use; D011379:Prognosis; D011994:Recombinant Proteins; D012008:Recurrence; D012074:Remission Induction
D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D015649:Pentostatin
Volosatokletochnyĭ leĭkoz (obzor literatury i sobstvennye dannye).