[The clinico-neurophysiological study of the effect of cerebrolysin on brain function in the acute and early recovery periods of hemispheric ischemic stroke].
Thirty patients with acute ischemic stroke and at early terms of postapoplectic recovery received cerebrolysin in daily doses 10, 20 and 30 ml for 5 days or 10 ml, i. v. for 10 days, respectively. The patients were examined for neurological status and cerebral function. In acute stroke the highest effect occurred in the affection of moderate severity. In severe stroke the drug stimulated recovery of impaired functions which tended to restore more quickly than in control subjects. In early convalescents cerebrolysin improved motor functions. Details of the results of the combined neurophysiological examination in the course of the treatment are discussed.
Gusev
E I
EI
Burd
G S
GS
Gekht
A B
AB
Skvortsova
V I
VI
Bogomolova
M A
MA
Selikhova
M V
MV
Fidler
S M
SM
D000208:Acute Disease; D000368:Aged; D000596:Amino Acids / Q000008:administration & dosage*; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D002545:Brain Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D003289:Convalescence; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D000596:Amino Acids; C006952:cerebrolysin
Kliniko-neĭrofiziologicheskoe issledovanie vliianiia tserebrolizina na funktsional'noe sostoianie golovnogo mozga v ostrom i rannem vosstanovitel'nom periodakh polusharnogo ishemicheskogo insul'ta.