title: Rapid reversal of bone scan abnormalities in a patient with type 1 primary hyperoxaluria and oxalosis.
abstract: Serial bone scanning was performed on a 23-year-old man with type 1 primary hyperoxaluria, renal failure, oxalosis, and cardiac failure. The initial bone scan (6/22/90) demonstrated diffuse increased uptake in the axial and peripheral skeleton, heart, and the soft tissues of the lower extremities. A combined liver and kidney transplant was successfully performed with subsequent resolution of the oxalosis, renal failure, and cardiac failure. A follow-up bone scan (9/24/90) demonstrated resolution of abnormal heart and soft tissue uptake, as well as decreased uptake in the long bones. This case demonstrates that bone scanning may be a useful tool in the management of patients with oxalosis. The scintigraphic findings closely paralleled the clinical response to treatment of the disease and suggested decreased total body stores of calcium oxalate.
authors.affiliation: Department of Diagnostic Radiology/Nuclear Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois.
authors.forename: G R
authors.initials: GR
authors.lastname: Solmos
authors.forename: A
authors.initials: A
authors.lastname: Ali
authors.forename: R A
authors.initials: RA
authors.lastname: Rodby
authors.forename: E W
authors.initials: EW
authors.lastname: Fordham
mesh_terms: D058186:Acute Kidney Injury / Q000000981:diagnostic imaging; D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000378:metabolism; D002081:Buttocks / Q000000981:diagnostic imaging; D002129:Calcium Oxalate / Q000032:analysis / Q000378:metabolism*; D002303:Cardiac Output, Low / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D006959:Hyperoxaluria / Q000145:classification / Q000000981:diagnostic imaging* / Q000601:surgery; D016030:Kidney Transplantation; D007866:Leg / Q000000981:diagnostic imaging; D016031:Liver Transplantation; D008297:Male; D011877:Radionuclide Imaging
chemical_list: D002129:Calcium Oxalate