title: [Signal transmission modalities induced by growth factors: from membrane to nucleus].
abstract: Growth factors transduce their biological signals through transmembrane receptors that possess an intrinsic or an associated protein-tyrosine kinase activity. Two complete signalling pathways, from membrane to nucleus, were elucidated in 1993. They are described in detail in this review.
authors.affiliation: INSERM Unité 244-CEA-DBMS/BRCE, CENG-17, Grenoble.
authors.forename: J J
authors.initials: JJ
authors.lastname: Feige
authors.forename: I
authors.initials: I
authors.lastname: Vilgrain
mesh_terms: D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000502:physiology; D002462:Cell Membrane; D002467:Cell Nucleus; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D017978:Receptors, Growth Factor / Q000737:chemistry / Q000145:classification / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D006133:Growth Substances; D017978:Receptors, Growth Factor; D017871:Calcium-Calmodulin-Dependent Protein Kinases
vernacular_title: Modalités de transmission du signal induit par les facteurs de croissance: de la membrane au noyau.