Sodium thiosulphate in the treatment of renal tubular acidosis I with nephrocalcinosis.
Nephrocalcinosis is a common feature in renal tubular acidosis I (RTA-I) and contributes to renal insufficiency. We describe a patient, 37 years old, with RTA-I, mild renal failure and extended nephrocalcinosis. His disease was diagnosed in age 28 and patient is under treatment with sodium bicarbonate, potassium gluconate and sodium thiosulphate for 9 years. By this treatment nephrocalcinosis and renal function have not been worsened and patient is without clinical symptoms.
Agroyannis
B J
BJ
University of Athens, School of Medicine, Aretaieon Hospital, Greece.
Koutsikos
D K
DK
Tzanatos
H A
HA
Konstadinidou
I K
IK
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000141:Acidosis, Renal Tubular / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D006801:Humans; D007669:Kidney Calculi / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008134:Long-Term Care; D008297:Male; D009397:Nephrocalcinosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011859:Radiography; D013885:Thiosulfates / Q000627:therapeutic use*
D000975:Antioxidants; D013885:Thiosulfates; C017717:sodium thiosulfate