title: Prospective analysis of antibiotic prophylaxis for orthognathic surgery.
abstract: A randomized prospective study of 30 patients was undertaken to evaluate antibiotic prophylaxis for orthognathic surgery. Perioperative, high-dosage antibiotic administration was compared to an existing prophylactic regimen employing longer intervals and continued postoperative antibiotics for 7 to 10 days. No significant difference was found between the two groups with respect to incidence of infection. Other variables studied included gender and age of patients, type of surgery performed, procedure length, and use of fixation.
authors.affiliation: Department of Hospital Dentistry, Division of Oral and Maxillofacial Surgery, University of Iowa Hospitals and Clinics, Iowa City.
authors.forename: K L
authors.initials: KL
authors.lastname: Fridrich
authors.forename: B E
authors.initials: BE
authors.lastname: Partnoy
authors.forename: D L
authors.initials: DL
authors.lastname: Zeitler
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002437:Cefazolin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D056948:Orthognathic Surgical Procedures; D010027:Osteotomy / Q000379:methods*; D010400:Penicillin G / Q000627:therapeutic use; D010404:Penicillin V / Q000627:therapeutic use; D011292:Premedication; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents; D002437:Cefazolin; D010400:Penicillin G; D010404:Penicillin V