[Infusion of hematopoietic stem cells from the blood. Simpler and better than bone marrow transplantation?].
Infusion of haematopoietic stem cells, either autologous or allogeneic, allows treatment of malignant diseases with marrow ablative doses of cytostatics or whole body irradiation. Hospitalization and general anaesthesia is necessary for bone marrow harvesting, while the harvest of peripheral stem cells may be performed without hospitalization. Mobilization of haematopoietic stem cells from the bone marrow to peripheral blood, followed by cytapheresis and harvesting of the stem-cell containing fraction is a promising alternative to the harvest of marrow. We have tried this in one patient with advanced acute myeloid leukaemia and discuss our experience and that of others.
Brinch
L
L
Medisinsk avdeling A, Rikshospitalet, Oslo.
Evensen
S A
SA
Egeland
T
T
Solheim
B G
BG
D001804:Blood Transfusion, Autologous / Q000379:methods*; D005069:Evaluation Studies as Topic; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D008297:Male; D008875:Middle Aged
Infusjon av hematopoetiske stamceller fra blod. Enklere og bedre enn beinmargstransplantasjon?