title: Two long-term clinical studies comparing the plaque removal and gingivitis reduction efficacy of the Oral-B Advantage Plaque Remover to five manual toothbrushes.
abstract: Two long-term studies were conducted to evaluate the therapeutic efficacy of five manual toothbrushes compared to the Oral-B Advantage Plaque Remover measuring plaque removal and gingivitis/bleeding reduction. Both studies were carried out under the same protocol and utilized the same examiners. In Study 1, the Oral-B Advantage Plaque Remover was compared to the Crest Complete and Colgate Precision toothbrushes. In Study 2, the Oral-B Advantage Plaque Remover was compared to the Reach Advanced Design, Colgate Plus and Jordan Exact toothbrushes. A total of 109 and 121 male and female subjects who met the inclusion and exclusion criteria completed Study 1 and Study 2, respectively. Subjects were initially screened for dental plaque eligibility having abstained from oral hygiene for a prior 24-hour period. Subjects were randomly assigned to one of the balanced groups and received a professional prophylaxis to reduce plaque scores. Subjects were then scheduled to return 4 weeks and 8 weeks later, having again abstained from all oral hygiene procedures for a prior period of 24 hours. At each visit, each subject was evaluated for plaque, gingivitis and bleeding. Upon completion of the study, the data were subjected to statistical analysis. The results of both studies are summarized as follows: The Oral-B Advantage Plaque Remover was significantly more effective than the Crest Complete, Colgate Precision, Colgate Plus and Jordan Exact toothbrushes in whole mouth plaque removal (p < 0.05), and vs. all brushes tested in gingivitis reduction (p < 0.01) and in reducing gingival bleeding (p < 0.001).
authors.forename: E
authors.initials: E
authors.lastname: Grossman
authors.forename: W
authors.initials: W
authors.lastname: Dembling
authors.forename: D R
authors.initials: DR
authors.lastname: Walley
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D003773:Dental Plaque / Q000628:therapy*; D003774:Dental Plaque Index; D005260:Female; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010512:Periodontal Index; D016037:Single-Blind Method; D014099:Toothbrushing / Q000295:instrumentation*