title: Combined pressure control/high frequency ventilation in adult respiratory distress syndrome and sickle cell anemia.
abstract: Acute chest syndrome complicating sickle cell anemia may progress to adult respiratory distress syndrome despite appropriate therapy. Extra-alveolar air leaks may complicate the care of these patients as conventional mechanical ventilation becomes increasingly difficult. We successfully treated a child with sickle cell anemia, acute chest syndrome, adult respiratory distress syndrome, and severe extra-alveolar air leaks using a new combined mode ventilatory approach: pressure control with high-frequency ventilation.
authors.affiliation: Department of Pediatrics, USC School of Medicine, Los Angeles.
authors.forename: J S
authors.initials: JS
authors.lastname: Baird
authors.forename: J L
authors.initials: JL
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Escudero
authors.forename: D R
authors.initials: DR
authors.lastname: Powars
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications*; D002675:Child, Preschool; D006612:High-Frequency Ventilation; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D011859:Radiography; D012121:Respiration, Artificial / Q000379:methods; D012128:Respiratory Distress Syndrome / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*