title: One-week therapy with oral terbinafine in cases of tinea cruris/corporis.
abstract: The use of oral terbinafine in the treatment of superficial dermatophyte infections has been extensively studied, using different treatment regimens. To evaluate the efficacy of short-term therapy with oral terbinafine in cases of tinea cruris/corporis, 22 patients (21 male and one female) with mycologically proven tinea cruris/corporis, were included in the present study. Each patient received one tablet of terbinafine 250 mg daily for 1 week. Patients were followed-up for 6 weeks after completion of treatment. Clinical and mycological assessments were performed at the end of treatment, and at the end of the follow-up period. The mean sum of scores of signs and symptoms in all patients decreased significantly from 12.36 before treatment to 0 at the end of the follow-up period, and mycological investigations were negative in all patients at the end of the follow-up period. Our results show that 1-week therapy with oral terbinafine is highly effective in the treatment of tinea cruris/corporis.
authors.affiliation: Department of Dermatology, Benha Faculty of Medicine, Egypt.
authors.forename: A
authors.initials: A
authors.lastname: Farag
authors.forename: M
authors.initials: M
authors.lastname: Taha
authors.forename: S
authors.initials: S
authors.lastname: Halim
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009281:Naphthalenes / Q000008:administration & dosage*; D000077291:Terbinafine; D014005:Tinea / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine