title: Rosmaricine derivatives as potential antitumoral agents.
abstract: A group of N-(alkylaminoacyl)-O,O-dimethylrosmaricines was prepared and, together with a set of rosmaricine derivatives previously described by us, evaluated for activity against lymphocytic leukemia P 388. Only one compound exhibited a borderline activity, while all the others were inactive.
authors.affiliation: Istituto di Scienze Farmaceutiche, Università di Genova.
authors.forename: A
authors.initials: A
authors.lastname: Boido
authors.forename: F
authors.initials: F
authors.lastname: Savelli
authors.forename: F
authors.initials: F
authors.lastname: Sparatore
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice; D008815:Mice, Inbred Strains; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; C087746:rosmaricine