Long-term xenograft survival and suppression of xenoantibody formation in the hamster-to-rat heart transplant model using a combination therapy of leflunomide and cyclosporine.
Lin
Y
Y
Transplantation Laboratory, Rega Institute, University of Leuven, Belgium.
Sobis
H
H
Vandeputte
M
M
Waer
M
M
D000818:Animals; D000910:Antibodies, Heterophile / Q000096:biosynthesis*; D006224:Cricetinae; D016572:Cyclosporine / Q000627:therapeutic use*; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D004359:Drug Therapy, Combination; D006085:Graft Survival / Q000187:drug effects* / Q000276:immunology; D016027:Heart Transplantation / Q000276:immunology*; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007555:Isoxazoles / Q000627:therapeutic use*; D000077339:Leflunomide; D008297:Male; D008647:Mesocricetus; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000276:immunology*
D000910:Antibodies, Heterophile; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D016572:Cyclosporine; D000077339:Leflunomide