title: [Gadolinium-DTPA combined with a fat suppression technique in studies with magnetic resonance at 0.5 T in soft-tissue neoplasms].
abstract: Combination of fat suppression techniques with intravenous paramagnetic contrast administration is usually performed using high-field MR systems. We combined a modified three-point Dixon technique for fat suppression with gadolinium-DTPA administration in the investigation of soft tissue neoplasms at 0.5 T. Nineteen patients with 21 neoplasms (14 primary malignant, 2 metastatic, 5 benign tumors) were examined. Examination protocol included unenhanced SE T1, PD and T2-weighted images. After the intravenous administration of gadolinium-DTPA (0.1 mmol/kg), a modified three-point Dixon technique provided three image sets, i.e., conventional T1-weighted SE images, fat-suppressed T1-weighted images and water-suppressed T1-weighted images. Two observers evaluated the lesions for conspicuity and size in three image groups: unenhanced T1-, PD and T2-weighted images, enhanced conventional T1-weighted images, enhanced T1-weighted images with fat suppression. Ten lesions showed greater conspicuity on enhanced fat-suppressed images than on unenhanced T1-, PD and T2- and enhanced conventional T1-weighted images. In 16 cases lesions were more conspicuous on enhanced water images than on conventional enhanced T1 images. Ten tumors exhibited a larger size (difference exceeding 20%) on enhanced fat-suppressed images. The combination of gadolinium with the modified Dixon technique improves the demonstration of soft tissue neoplasms at 0.5 T and allows lesion size to be measured more accurately.
authors.affiliation: Cattedra di Radiologia, Università di Pisa.
authors.forename: L
authors.initials: L
authors.lastname: Battolla
authors.forename: V
authors.initials: V
authors.lastname: Zampa
authors.forename: M
authors.initials: M
authors.lastname: Mascalchi
authors.forename: F
authors.initials: F
authors.lastname: Falaschi
authors.forename: P
authors.initials: P
authors.lastname: Bagnolesi
authors.forename: C
authors.initials: C
authors.lastname: Tessa
authors.forename: A
authors.initials: A
authors.lastname: Paolicchi
authors.forename: C
authors.initials: C
authors.lastname: Bartolozzi
mesh_terms: D000273:Adipose Tissue; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
vernacular_title: Associazione di gadolinio-DTPA con tecnica di soppressione del grasso nello studio con risonanza magnetica a 0.5 T nelle neoplasie dei tessuti molli.