[Signal transmission modalities induced by growth factors: from membrane to nucleus].
Growth factors transduce their biological signals through transmembrane receptors that possess an intrinsic or an associated protein-tyrosine kinase activity. Two complete signalling pathways, from membrane to nucleus, were elucidated in 1993. They are described in detail in this review.
Feige
J J
JJ
INSERM Unité 244-CEA-DBMS/BRCE, CENG-17, Grenoble.
Vilgrain
I
I
D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000502:physiology; D002462:Cell Membrane; D002467:Cell Nucleus; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D017978:Receptors, Growth Factor / Q000737:chemistry / Q000145:classification / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
D006133:Growth Substances; D017978:Receptors, Growth Factor; D017871:Calcium-Calmodulin-Dependent Protein Kinases
Modalités de transmission du signal induit par les facteurs de croissance: de la membrane au noyau.