Ultrastructural analysis of periapical granulomas.
A large portion of periapical granulomas is composed by cells of the mononuclear-phagocyte and lymphoid system. The ultrastructural features of the monocytes/macrophages differ in relationship to the state of activity of the cells (phagocytosis or secretion). A close correlation between cells of these two systems can be surmised by their tight contacts. An important role in the bone resorption is probably played by cytokines like IL-1 and TNF.
Piattelli
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Dental School, University of Chieti, Italy.
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D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008407:Mast Cells / Q000648:ultrastructure; D008854:Microscopy, Electron; D010484:Periapical Granuloma / Q000473:pathology*; D010486:Periapical Tissue / Q000648:ultrastructure*; D010586:Phagocytes / Q000648:ultrastructure