[Correlation between the serum level of soluble CD16 and the staging of myeloma: study of 214 serums].
Soluble CD16 (sCD16) are soluble part of Fc receptor for IgG which control in mice, proliferation of hybridoma B cells and IgG production. The levels of sCD16 in 165 myeloma patients and 29 patients with MGUS appear significantly different:25a.u./ml versus 144a.u./ml and values of stage I are significantly higher than those of stages II + III.sCD16 might be a prognosis factor in myeloma.
Mathiot
C
C
Unité Inserm U255 et Département de biologie clinique, Institut Curie, Paris.
Grosbois
B
B
Teillaud
J L
JL
Tartour
E
E
Mosseri
V
V
Euller-Ziegler
L
L
Daragon
A
A
Michaux
J L
JL
Facon
T
T
Bernard
J F
JF
D000906:Antibodies / Q000032:analysis; D006801:Humans; D009101:Multiple Myeloma / Q000276:immunology* / Q000473:pathology; D009367:Neoplasm Staging; D017452:Receptors, IgG / Q000276:immunology*
D000906:Antibodies; D017452:Receptors, IgG
Corrélation entre le taux sérique du CD16 soluble et le stade du myélome: étude de 214 sérums.