Bacteroides fragilis arthritis in a sickle cell-thalassaemia patient.
Anaerobic arthritis due to Bacteroides fragilis was diagnosed in a 33-year-old patient with prolonged fever suffering from sickle cell/thalassaemia. The causative agent was isolated from blood and purulent synovial fluid from both knee joints. A combination of chloramphenicol plus metronidazole treatment proved effective. Anaerobic arthritis has not previously been described in patients with sickle cell disease, and may reflect the well-known susceptibility of these patients to pathogens.
Konstantopoulos
K
K
First University Department of Medicine, Laikon Hospital, Athens, Greece.
Avlami
A
A
Demarongona
K
K
Sideris
G
G
Rekoumi
L
L
Stefanou
J
J
Voskaridou
E
E
Loukopoulos
D
D
D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000382:microbiology*; D001442:Bacteroides Infections / Q000150:complications* / Q000188:drug therapy; D001441:Bacteroides fragilis; D002701:Chloramphenicol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007719:Knee Joint / Q000382:microbiology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D013582:Synovial Fluid / Q000382:microbiology; D013789:Thalassemia / Q000150:complications*
D008795:Metronidazole; D002701:Chloramphenicol