title: [Hairy-cell leukemia (a review of the literature and the authors' own data)].
abstract: Gene engineering interferon made in Russia (reaferon, realdiron) was given to 40 patients with hairy-cell leukemia. Complete and partial remissions were achieved in 56% and 28% of the patients, respectively. Minimum effect was reported in 3% of the cases. In 5 cases with primary resistance or recurrences the authors used pentostatin which produced complete remissions in all the five patients.
authors.forename: M A
authors.initials: MA
authors.lastname: Volkova
authors.forename: S V
authors.initials: SV
authors.lastname: Lepkov
authors.forename: M A
authors.initials: MA
authors.lastname: Frenkel'
authors.forename: N B
authors.initials: NB
authors.lastname: Lebedeva
authors.forename: N N
authors.initials: NN
authors.lastname: Tupitsyn
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007943:Leukemia, Hairy Cell / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015649:Pentostatin / Q000627:therapeutic use; D011379:Prognosis; D011994:Recombinant Proteins; D012008:Recurrence; D012074:Remission Induction
chemical_list: D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D015649:Pentostatin
vernacular_title: Volosatokletochnyĭ leĭkoz (obzor literatury i sobstvennye dannye).