[C-fos expression in rat brain during seizure and electroacupuncture].
C-fos proteins were visualized immunohistochemically in the brain of rats after seizures induced by injecting penicillin into hippocampus and by penicillin+electroacupuncture treatment. Three hours following seizures there was an evident expression of c-fos proteins in the hippocampus (CA1 area), dentate gyrus, piriform cortex, dorsal part of entorhinal cortex, and amygdaloid nucleus, and there was a dramatic increase of c-fos proteins in CA3 area and the areas mentioned above except the CA1 area where c-fos proteins apparently decreased after electroacupuncture treatment. The results showed that seizures can induce c-fos proteins in some nuclei related with seizure and that electroacupuncture can also regulates the c-fos expression after seizure.
Wang
B E
BE
Department of Neurobiology, Shanghai Medical University, China.
Cheng
J S
JS
D000818:Animals; D001921:Brain / Q000378:metabolism*; D015671:Electroacupuncture; D004827:Epilepsy / Q000139:chemically induced / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation; D006624:Hippocampus / Q000378:metabolism; D008297:Male; D010406:Penicillins; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis* / Q000235:genetics; D051381:Rats; D017208:Rats, Wistar
D010406:Penicillins; D016760:Proto-Oncogene Proteins c-fos