Determination of pharmacokinetic drug interactions with carbamazepine and phenytoin using stable isotope labeling and simple high-performance liquid chromatography/ultraviolet detection technique.
Browne
T R
TR
Department of Neurology, Boston University School of Medicine, MA.
Szabo
G K
GK
Davoudi
H
H
Josephs
E G
EG
D000284:Administration, Oral; D000704:Analysis of Variance; D002220:Carbamazepine / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003903:Deuterium; D004347:Drug Interactions; D006801:Humans; D007553:Isotope Labeling; D008657:Metabolic Clearance Rate; D010672:Phenytoin / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D013056:Spectrophotometry, Ultraviolet
D002220:Carbamazepine; D010672:Phenytoin; D003903:Deuterium