title: [Exacerbation of an affective psychosis after terminating a decade of benzodiazepine treatment. Which therapeutic procedure is sensible?].
abstract: We report the case of a 61-year old patient with an affective disorder who had been treated with benzodiazepines in low dosages over a 16 year period. This treatment had been prescribed by his physician following several depressive episodes. During this time, the patient remained able to work and exhibited little psychopathological symptomatology. Following discontinuation of medication, however, the depressive phases resumed and were particularly intractable. The clinical implications of this case and the therapeutic strategies for approaching patients with long-term benzodiazepine treatment are discussed.
authors.affiliation: Psychiatrische Klinik und Poliklinik, Universität München.
authors.forename: M
authors.initials: M
authors.lastname: Soyka
authors.forename: R
authors.initials: R
authors.lastname: Lehle
authors.forename: H
authors.initials: H
authors.lastname: Hippius
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000188:drug therapy / Q000523:psychology; D003866:Depressive Disorder / Q000139:chemically induced* / Q000188:drug therapy / Q000523:psychology; D004359:Drug Therapy, Combination; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011222:Prazepam / Q000009:adverse effects* / Q000627:therapeutic use; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000523:psychology; D019966:Substance-Related Disorders / Q000523:psychology / Q000534:rehabilitation*
chemical_list: D000928:Antidepressive Agents; D008094:Lithium; D011222:Prazepam
vernacular_title: Exazerbation einer affektiven Psychose nach Beendigung einer jahrzehntelangen Benzodiazepinbehandlung. Welches therapeutische Vorgehen ist sinnvoll?