Dynamical order and disorder in lipid bilayers.
Various order and disorder phenomena in lipid bilayers are considered as they arise due to the very many-particle character of the bilayer. Particular attention is paid to dynamically maintained order in terms of lateral density- and compositional fluctuations that lead to dynamic heterogeneity, local structure, and lipid-domain formation on length scales of 10-1000 A. The influence of cholesterol and various drugs on the local structure is described. A discussion is presented of the possible role played by lipid order and disorder phenomena for the functional dynamics of membranes.
Mouritsen
O G
OG
Department of Physical Chemistry, Technical University of Denmark, Lyngby.
Jørgensen
K
K
D000777:Anesthetics; D002784:Cholesterol; D006221:Halothane; D008051:Lipid Bilayers / Q000737:chemistry*; D008954:Models, Biological; D013329:Structure-Activity Relationship; D013816:Thermodynamics
D000777:Anesthetics; D008051:Lipid Bilayers; D002784:Cholesterol; D006221:Halothane