Prevention of autoimmune destruction of transplanted islets in spontaneously diabetic NOD mice by KH1060, a 20-epi analog of vitamin D: synergy with cyclosporine.
Mathieu
C
C
Laboratory for Experimental Medicine and Endocrinology, K.U. Leuven, Belgium.
Laureys
J
J
Waer
M
M
Bouillon
R
R
D000818:Animals; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000628:therapy*; D004357:Drug Synergism; D006085:Graft Survival / Q000187:drug effects* / Q000276:immunology; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016381:Islets of Langerhans Transplantation / Q000276:immunology*; D051379:Mice; D016688:Mice, Inbred NOD; D013997:Time Factors; D014185:Transplantation, Isogeneic
D007166:Immunosuppressive Agents; C074279:KH 1060; D016572:Cyclosporine; D002117:Calcitriol