title: Relaxin concentrations in exoembryonic fluids during the first trimester.
abstract: In 15 women undergoing therapeutic termination of pregnancy (8-13 weeks), the median concentration of relaxin was 1000 ng/l in maternal serum, 122 ng/l in coelomic fluid and 9 ng/l in amniotic fluid. Its presence in coelomic fluid suggests that relaxin may be present in the fetal circulation and thus be able to influence embryonic development during the period of organogenesis.
authors.affiliation: Department of Academic Obstetrics and Gynaecology, Chelsea and Westminster Hospital, London, UK.
authors.forename: M R
authors.initials: MR
authors.lastname: Johnson
authors.forename: E
authors.initials: E
authors.lastname: Jauniaux
authors.forename: D
authors.initials: D
authors.lastname: Jurkovic
authors.forename: P
authors.initials: P
authors.lastname: Sannino
authors.forename: S
authors.initials: S
authors.lastname: Campbell
authors.forename: K H
authors.initials: KH
authors.lastname: Nicolaides
mesh_terms: D000028:Abortion, Induced; D000653:Amniotic Fluid / Q000737:chemistry*; D001826:Body Fluids / Q000737:chemistry*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012065:Relaxin / Q000032:analysis* / Q000097:blood
chemical_list: D012065:Relaxin