title: Two AIDS patients with life-threatening pancreatitis successfully treated, one with ganciclovir the other with foscarnet.
abstract: Two AIDS patients, clinically suspected to have cytomegalovirus (CMV) pancreatitis are described. The first patient was successfully treated with ganciclovir 10 mg/kg/day. This patient refused ganciclovir maintenance treatment and developed 3 other episodes of pancreatitis which responded each time to ganciclovir. The second patient was successfully treated with foscarnet 200 mg/kg/day followed by maintenance foscarnet treatment 100 mg/kg/day. No pancreatitis relapse was observed.
authors.affiliation: Instituut voor Tropische Geneeskunde, Antwerp, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Colebunders
authors.forename: K
authors.initials: K
authors.lastname: Van den Abbeele
authors.forename: Y
authors.initials: Y
authors.lastname: Fleerackers
authors.forename: K
authors.initials: K
authors.lastname: Bols
authors.forename: M
authors.initials: M
authors.lastname: Lachenal
authors.forename: L
authors.initials: L
authors.lastname: Van Damme
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000821:virology; D000328:Adult; D003586:Cytomegalovirus Infections / Q000188:drug therapy*; D005260:Female; D017245:Foscarnet / Q000627:therapeutic use*; D015774:Ganciclovir / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000188:drug therapy* / Q000821:virology; D012008:Recurrence
chemical_list: D017245:Foscarnet; D015774:Ganciclovir