An inappropriate thyrotropin-secreting pituitary adenoma in a 30-year-old man.
Thyrotropin-secreting pituitary adenomas are rare, especially in the family practice setting. We report a case of such a tumor and review the literature. The key clinical finding is hyperthyroidism in the absence of a suppressed thyrotropin level. The patient was unusual in not having an elevated alpha-subunit. All patients with hyperthyroidism should be screened for a thyrotropin level to rule out this unusual cause of hyperthyroidism. Other aspects of this case pertinent to primary care management are reviewed.
Fahey
P
P
Department of Family Medicine, Ohio State University Hospital, Columbus.
Sarkos
P
P
Mazzaferri
E
E
D000236:Adenoma / Q000378:metabolism* / Q000601:surgery; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000378:metabolism* / Q000601:surgery; D013963:Thyroid Hormones / Q000097:blood; D013971:Thyrotoxicosis / Q000209:etiology*; D013972:Thyrotropin / Q000378:metabolism*
D013963:Thyroid Hormones; D013972:Thyrotropin