title: Uterine rupture and labor induction with prostaglandins.
abstract: Uterine rupture in patients with labor induction with prostaglandin E2 application though uncommon is a very serious complication and preventable in obstetrics. We reported three cases of spontaneous uterine rupture following induction of labor with intracervical PGE2 gel administration in a dosage of 3-6 mg and two in whom labor was augmented with oxytocin infusion. To avoid such a complication, intracervical PGE2 gel administration should be started with a smaller dose and should augmentation with oxytocin be required careful evaluation and monitoring by a specialist is desirable.
authors.affiliation: Department of Obstetrics & Gynaecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: W
authors.initials: W
authors.lastname: Phuapradit
authors.forename: Y
authors.initials: Y
authors.lastname: Herabutya
authors.forename: N
authors.initials: N
authors.lastname: Saropala
mesh_terms: D000328:Adult; D015232:Dinoprostone / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000009:adverse effects*; D011247:Pregnancy; D014597:Uterine Rupture / Q000139:chemically induced / Q000209:etiology*
chemical_list: D015232:Dinoprostone