[Research on hemostatic mechanism of extracts from carbonized Schizonepeta tenuifolia Brig].
It has been shown that StE can significantly shorten PT, TT, KPTT and RT of experimental animals and has an antiheparin function in the body. Meanwhile, it can significantly shorten ELT and strengthen FA. Its hemostatic action is accomplished through promoting coagulation and inhibiting fibrinolysis. 3P test and EG test were negative, it is thus impossible for a large dosage of StE to lead to DIC.
Ding
A W
AW
Nanjing College of Traditional Chinese Medicine.
Wu
H
H
Kong
L D
LD
Wang
S L
SL
Gao
Z Z
ZZ
Zhao
M X
MX
Tan
M
M
D000818:Animals; D001780:Blood Coagulation Tests; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects; D006490:Hemostatics / Q000494:pharmacology*; D008297:Male; D051379:Mice; D011817:Rabbits; D051381:Rats; D017207:Rats, Sprague-Dawley; D012712:Serum Globulins / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D006490:Hemostatics; D012712:Serum Globulins