[Hepatic polycystic disease is not always associated with polycystic kidney: epidemiological data].
Adult polycystic disease of the liver (APLD) and of the kidney (ADPKD) is considered to represent one entity. In 75 ADPKD kindreds with 259 affected members, ultrasonography and/or CT were performed in 186 (71.8%) from 64 kindreds (85.3%). We demonstrated that ADPKD with or without APLD are two separate phenotypes and suggest genetic heterogeneity of these two entities.
Simon
P
P
Service de néphrologie, Centre hospitalier La Beauchée, St Brieuc.
Ang
K S
KS
Charasse
C
C
Ghali
N
N
Catroux
B
B
Houitte
H
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003560:Cysts / Q000209:etiology* / Q000235:genetics; D005260:Female; D005602:France; D006801:Humans; D008107:Liver Diseases / Q000209:etiology* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications* / Q000235:genetics
La polykystose hépatique n'est pas toujours associée à la polykystose rénale: données épidémiologiques.