[Clinical characteristicsand course of extrapulmonary/disseminated tuberculosis in patients with AIDS. Study of 103 cases diagnosed in the province of Cadiz].
Tuberculosis constitutes a public health problem that has become more serious in the past couple of years primarily due to the pandemic of human immunodeficiency virus (HIV). This study analyzes the evolutionary, clinical, and epidemiological characteristics of the extrapulmonary and disseminated forms of tuberculosis (TBD/E) in AIDS patients diagnosed in the province of Cádiz. Data for 103 patients who manifested both diseases were gathered prospectively. The prevalence of TBD/E was 30 percent among patients with AIDS. The primary risk factor was addiction to parenteral drugs (91 percent). Seventy-five percent of the patients were diagnosed with disseminated forms of the illness and 25 percent with extrapulmonary forms. The organs affected tended to be lymphatic ganglions and the lungs. Worthy of note is the lateness in seeking medical attention (45.6 +/- 4.5 days; range: 4-240 days). We conclude that tuberculosis constitutes a common pathology with an appreciable mortality in AIDs patients. Disseminated forms of tuberculosis predominate and may adopt a wide range of clinical manifestations. The lateness with which patients seek medical attention is a fact worth emphasizing.
Canueto Quintero
J
J
Bascuñana Quirell
A
A
Vergara de Campos
A
A
Torres-Tortosa
M
M
Escribano Moriana
J C
JC
Sánchez Porto
A
A
Pérez Cortés
S
S
Pérez Jiménez
J
J
Lorente Campos
J
J
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000401:mortality; D000328:Adult; D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011446:Prospective Studies; D013030:Spain; D015996:Survival Rate; D014376:Tuberculosis / Q000150:complications* / Q000453:epidemiology
Características clínicas y evolutivas de la tuberculosis extrapulmonar/diseminada en los pacientes con SIDA. Estudio de 103 casos diagnosticados en la provincia de Cádiz.