Antibiotic induced meningitis.
Three patients with antibiotic induced meningitis, one following penicillin with seven episodes, are reported on--the first well documented description of penicillin induced meningitis. In this patient episodes of headache and nuchal rigidity appeared with and without CSF pleocytosis. Two patients had a total of five episodes of antibiotic induced meningitis after trimethoprim-sulphamethoxazole (co-trimoxazole) administration. The features common to all three patients were myalgia, confusion and low CSF glucose. CSF analysis was not a reliable method to differentiate antibiotic induced meningitis from partially treated bacterial meningitis.
River
Y
Y
Department of Neurology, Hadassah University Hospital, Hebrew University, Jerusalem, Israel.
Averbuch-Heller
L
L
Weinberger
M
M
Meiner
Z
Z
Mevorach
D
D
Schlesinger
I
I
Argov
Z
Z
D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000166:cytology; D003221:Confusion / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005947:Glucose / Q000032:analysis; D006261:Headache / Q000209:etiology; D006801:Humans; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000139:chemically induced* / Q000150:complications / Q000453:epidemiology; D009127:Muscle Rigidity; D009334:Neck Muscles; D010406:Penicillins / Q000009:adverse effects*; D012008:Recurrence; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects*
D010406:Penicillins; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D005947:Glucose