title: Insect sting allergy: analysis of a cohort of patients who initiated venom immunotherapy from 1978 to 1986.
abstract: BACKGROUND
  The proper duration of venom immunotherapy remains uncertain.
  
  
  OBJECTIVE
  We report our experience with a cohort of patients who started venom immunotherapy from 1978 to 1986.
  
  
  METHODS
  In a midwestern allergy practice, the cohort of 204 stinging insect-allergic patients who commenced venom immunotherapy from 1978 to 1986 were identified and evaluated by retrospective chart analysis and patient telephone inquiry.
  
  
  RESULTS
  Only 12 patients remain on venom treatment. The majority of patients have discontinued venom immunotherapy either by self-determination (35 patients) or upon physician advice (80 patients). There was no relationship between the severity of the initial sting reaction and the length of time patients received therapy. After cessation of venom treatment, there were 148 re-stings in 117 patients with only two re-sting reactions, both of which occurred in patients with severe initial sting reactions.
  
  
  CONCLUSIONS
  Most patients who have received four to 6 years of venom immunotherapy continue to tolerate insect stings after cessation of treatment.
authors.affiliation: Allergy Department, Park Nicollet Medical Center, Minneapolis, Minnesota.
authors.forename: D F
authors.initials: DF
authors.lastname: Graft
authors.forename: W F
authors.initials: WF
authors.lastname: Schoenwetter
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001180:Arthropod Venoms / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D006801:Humans; D007167:Immunotherapy; D007299:Insect Bites and Stings / Q000453:epidemiology / Q000628:therapy*; D008875:Middle Aged; D008910:Minnesota / Q000453:epidemiology
chemical_list: D001180:Arthropod Venoms