Isolated motor control dysfunction related to progressive multifocal leukoencephalopathy during AIDS with normal MRI.
We describe the case of a human immunodeficiency virus-infected 34-year-old man with progressive multifocal leukoencephalopathy (PML). His case displayed unusual features, including a bizarre movement disorder, predominant involvement of the subcortical U fibers on neuropathologic examination, and the absence of MRI abnormalities suggestive of PML. Anatomic-clinical correlations are discussed.
de Toffol
B
B
Clinique Neurologique, C.H.U. Bretonneau, Tours, France.
Vidailhet
M
M
Gray
F
F
Besnier
J M
JM
Menage
P
P
Lescs
M C
MC
Choutet
P
P
Autret
A
A
D015526:AIDS Dementia Complex / Q000473:pathology* / Q000503:physiopathology*; D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology / Q000503:physiopathology*; D000328:Adult; D001921:Brain / Q000473:pathology* / Q000821:virology; D017809:Fatal Outcome; D006801:Humans; D017403:In Situ Hybridization; D007577:JC Virus / Q000302:isolation & purification; D008279:Magnetic Resonance Imaging; D008297:Male; D009069:Movement Disorders / Q000473:pathology / Q000503:physiopathology*; D012016:Reference Values