title: [Prevention of thromboembolic disease using mini doses of heparin in surgery patients].
abstract: In our study, the effect of the prophylaxis with the low doses of heparin on the occurrence of the deep venous thrombosis or the thromboembolic disease (TED) in the selected groups of the patients was investigated. From our work arises that the patients suffering from malignant diseases are actually at the high risk according to the shortened values of APTT in the preoperative period, which shows evidence of hypercoagulability and further according to the major occurrence of the deep venous thrombosis and the thromboembolic disease during the insufficient prevention by heparin (II. gr. 12%). Low doses of heparin evidently affected the values of APTT and elevated them to the more desirable levels in most of the patients. During the therapy by heparin is necessary to control regularly the values of APTT and to correct the dosage conditionally. Failure and complications of the therapy by heparin is mostly due to incorrectly dosed heparin or its delayed administration or further its improper and inadequate application in the group of the patients being contraindicated (mainly the patients suffering from the bleeding disorders or hepatic damage). The dosage of heparin must be consistent, then the therapy is safe and effective. At any postoperative complication it is necessary to applicate heparin again in the case of its previous abortion. It is also necessary to monitor the mobility of the patients after the operation, which is individual and according to correct the length of the administration of heparin. The period of the administration of heparin is individual, not overall. It is needless to afraid of the application of heparin in the surgical patients.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: I. chirurgická klinika 1. lékarské fakulty Univerzity Karlovy, Praha.
authors.forename: J
authors.initials: J
authors.lastname: Klofanda
mesh_terms: D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D013923:Thromboembolism / Q000517:prevention & control*
chemical_list: D006493:Heparin
vernacular_title: Profylaxe tromboembolické nemoci miniheparinizací u chirurgicky nemocných.