title: Influence of protein calorie malnutrition and fasting on the activities of delta-aminolevulinic acid dehydratase and porphobilinogen deaminase in rats.
abstract: Rats were fed a restricted standard diet (6-8 g daily) for 4 weeks. The erythrocyte activity of delta-aminolevulinic acid dehydratase showed a very expressed decrease (7.9 times) and its hepatic activity diminished more than twice. Porphobilinogen deaminase activity was reduced by 40% and 17% respectively. After a 3-day total food deprivation delta-aminolevulinic acid dehydratase activity remained unchanged in red blood cells, but an increase by 52% was found in the liver. The erythrocyte activity of porphobilinogen deaminase was reduced by 42% and its hepatic activity--by 16%.
authors.affiliation: Centre of Hygiene, Ecology and Nutrition, Sofia, Bulgaria.
authors.forename: D G
authors.initials: DG
authors.lastname: Adjarov
authors.forename: E N
authors.initials: EN
authors.lastname: Naydenova
authors.forename: M A
authors.initials: MA
authors.lastname: Kerimova
authors.forename: K D
authors.initials: KD
authors.lastname: Pentieva
authors.forename: L B
authors.initials: LB
authors.lastname: Ivanova
authors.forename: A V
authors.initials: AV
authors.lastname: Ivanova
mesh_terms: D000818:Animals; D004912:Erythrocytes / Q000201:enzymology; D005215:Fasting / Q000378:metabolism*; D005260:Female; D011163:Hydroxymethylbilane Synthase / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D000623:Porphobilinogen Synthase / Q000097:blood / Q000378:metabolism*; D011502:Protein-Energy Malnutrition / Q000201:enzymology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D011163:Hydroxymethylbilane Synthase; D000623:Porphobilinogen Synthase