title: Serum thymidine kinase in congenital dyserythropoietic anaemia type III.
abstract: Serum thymidine kinase (TK) was determined in a family with congenital dyserythropoietic anaemia type III (CDA, type III). 20 patients and 10 of their healthy siblings were investigated. Elevated TK was found in all 20 patients (median 56.2 U) but their healthy siblings had normal values (median 2.65 U). We suggest that determination of TK should be used for discrimination between healthy siblings and individuals affected by CDA type III when bone marrow examination is not suitable.
authors.affiliation: Department of Family Medicine, University Hospital, Umeå, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Sandström
authors.forename: A
authors.initials: A
authors.lastname: Wahlin
authors.forename: M
authors.initials: M
authors.lastname: Eriksson
authors.forename: I
authors.initials: I
authors.lastname: Bergström
mesh_terms: D000742:Anemia, Dyserythropoietic, Congenital / Q000175:diagnosis / Q000201:enzymology* / Q000235:genetics; D000743:Anemia, Hemolytic / Q000201:enzymology; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D013937:Thymidine Kinase / Q000097:blood*; D014805:Vitamin B 12 / Q000097:blood
chemical_list: D007770:L-Lactate Dehydrogenase; D013937:Thymidine Kinase; D014805:Vitamin B 12