Effect of a low molecular weight peptide bound to liver mitochondrial DNA on in vitro DNA duplication.
Authors tested "in vitro" action of a low molecular weight peptide fraction extracted by mitochondrial DNA from calf liver. The fraction acts upon duplication performed by E. Coli DNA polymerase I on poli dAT dAT template inhibiting chain elongation. The authors hypothesize that a similar role is exerted by this fraction "in vitro" on mitochondrial DNA template.
Spena
A
A
Department of Cell Biology, University of Calabria, Rende, CS.
Pedace
V
V
Covello
C
C
De Cicco
T
T
Mazzulla
S
S
Martino
G
G
D000818:Animals; D002417:Cattle; D004261:DNA Replication / Q000187:drug effects*; D004272:DNA, Mitochondrial / Q000032:analysis*; D008930:Mitochondria, Liver / Q000737:chemistry*; D008970:Molecular Weight; D010455:Peptides / Q000494:pharmacology*
D004272:DNA, Mitochondrial; D010455:Peptides