title: [Extrinsic allergic alveolitis caused by Penicillium frequentans. Review and presentation of a case].
abstract: We present a case of extrinsic allergic alveolitis due to Penicillium frequentans exposure (suberosis) at a cork factory. Diagnosis was based on clinical history, a restrictive spirometric pattern, evidence of reticular-nodular lung infiltrates on the X-ray, intradermal skin tests with dual reaction and precipitins-positive serum samples in the presence of the P. frequentans fungus. Although the patient refused to submit to a specific bronchial challenge, two natural challenges occurred when he once again happened to handle wet cork after leaving his previous job. The literature referring to this disease is reviewed.
authors.affiliation: Sección de Alergología, Hospital Virgen del Valle, Toledo.
authors.forename: A J
authors.initials: AJ
authors.lastname: Moral
authors.forename: J
authors.initials: J
authors.lastname: Arias
authors.forename: M A
authors.initials: MA
authors.lastname: García
authors.forename: R
authors.initials: R
authors.lastname: Abengózar
authors.forename: C
authors.initials: C
authors.lastname: Pérez-Carral
authors.forename: C J
authors.initials: CJ
authors.lastname: Senent
mesh_terms: D000328:Adult; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000175:diagnosis / Q000209:etiology*; D009790:Occupations; D010407:Penicillium; D011859:Radiography; D012882:Skin Tests; D013147:Spirometry
vernacular_title: Alveolitis alérgica extrínseca por Penicillium frequentans. Revisión y presentación de un caso.