title: Aldecalmycin, a new antimicrobial antibiotic from Streptomyces. III. Determination of absolute configuration.
abstract: The planar structure of aldecalmycin (1) had been determined in the previous paper, together with the conformations of the substituted trans decalin ring having one double bond and the sugar: beta-glucopyranoside type. The absolute configuration of 1 was a following problem to be solved. X-Ray crystallographic analysis of crystalline 4'-6'-O-benzylidenedihydroaldecalmycin (4) revealed the relative configuration. On the other hand, the stereoisomerism of the sugar was determined to be D by the optical rotation value of tetra-O-acetyl-alpha-methylglucopyranoside derived from 1. These results established the absolute configuration of 1.
authors.affiliation: Institute of Microbial Chemistry, Tokyo, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Sawa
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: K T
authors.initials: KT
authors.lastname: Nakamura
authors.forename: H
authors.initials: H
authors.lastname: Naganawa
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008968:Molecular Conformation; D011714:Pyrans / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D011714:Pyrans; C073564:aldecalmycin