Splenectomy for treatment of immunoblastic lymphadenopathy.
A 5-month-old girl was diagnosed with immunoblastic lymphadenopathy (IBL) on the basis of clinical symptoms and pathological findings. alpha-interferon, immunosuppressive agents such as cyclosporin A, deoxyspagarine, and azathioprine, and an alternating regimen of low-dose 6-mercaptopurine, cyclophosphamide and methotrexate were tried with partial success. Finally, splenectomy was carried out at 58 months of age, inducing prolonged complete remission without any medication.
Hirose
M
M
Department of Paediatrics, Tokushima University School of Medicine, Japan.
Nakagawa
R
R
Okada
A
A
Sano
T
T
Kuroda
Y
Y
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000473:pathology / Q000601:surgery*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D008198:Lymph Nodes / Q000473:pathology; D012008:Recurrence; D013156:Splenectomy
D007166:Immunosuppressive Agents