title: Antigenic relationship between mugwort and ragweed pollens by crossed immunoelectrophoresis.
abstract: Mugwort and ragweed pollens have been considered as important respiratory allergens in Korea. These two pollens are abundant in the air of Seoul from August through October. Many ragweed-sensitive patients have shown concurrent sensitivities to mugwort pollen. However the antigenic relationship between these two pollens has not been clarified. To observe the cross-reactivity between them, we developed polyclonal anti-mugwort and anti-ragweed antibodies by immunization on New Zealand white rabbits, and performed crossed immunoelectrophoresis(CIE) with two pollen extracts. Five precipitation lines were formed by mugwort and anti-mugwort antibody. One precipitation line was formed by ragweed and anti-ragweed antibody. There was no reaction from mugwort and anti-ragweed antibody, and from ragweed and anti-mugwort antibody. These results indicate that there is no cross-antigenicity between mugwort and ragweed pollens.
authors.affiliation: Department of Internal Medicine National Medical Center, Seoul, Korea.
authors.forename: H S
authors.initials: HS
authors.lastname: Park
authors.forename: M J
authors.initials: MJ
authors.lastname: Kim
authors.forename: H B
authors.initials: HB
authors.lastname: Moon
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology; D003429:Cross Reactions; D007123:Immunoelectrophoresis, Two-Dimensional; D011058:Pollen / Q000276:immunology*; D011817:Rabbits
chemical_list: D000906:Antibodies