title: [Comprehensive treatment for diabetes limb gangrene].
abstract: Anisodamine was used to improve general circulation and the microcirculation of affected limbs. Measures like local debridement, dressing change, and control of diabetes were applied in 351 patients with diabetic limb gangrene. Of the 351 patients, 301 (85.7%) were cured, 27(7.7%) were improved, 7(2.0%) failed, 6(1.7%) had limb amputated, and 10(2.9%) died. In the treatment, the nail-fold microcirculation was markedly improved. Doppler scan showed increased width and bloodflow of the vessels of the affected limbs. The criteria for the classification and diagnosis of diabetes limb gangrene are suggested.
authors.affiliation: Diabetes Research Institute, Airforce General Hospital, PLA, Beijing.
authors.forename: S M
authors.initials: SM
authors.lastname: Li
authors.forename: X
authors.initials: X
authors.lastname: Zhu
authors.forename: G Z
authors.initials: GZ
authors.lastname: Shi
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology / Q000628:therapy*; D017719:Diabetic Foot / Q000473:pathology* / Q000628:therapy*; D005260:Female; D005734:Gangrene; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D009262:Nails / Q000098:blood supply*; D012991:Solanaceous Alkaloids / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D012991:Solanaceous Alkaloids; D014665:Vasodilator Agents; C003922:anisodamine