Prolonged intracoronary infusion of streptokinase: an alternative pharmacologic approach to extensive thrombus in native coronary artery.
Several reports suggest that pretreatment of intracoronary thrombus with fibrinolytic agents may reduce the risk for complications during subsequent balloon angioplasty. We report a case, for the first time, of successful lysis of an extensive thrombus in a native coronary artery by administering a prolonged intracoronary infusion of streptokinase to facilitate subsequent angioplasty and discuss the management strategy when intracoronary thrombus is encountered.
Kjellgren
O
O
Beth Israel Medical Center, New York, New York 10003.
Wilentz
J R
JR
Kaganovsky
L
L
Sherman
W
W
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003131:Combined Modality Therapy; D003328:Coronary Thrombosis / Q000188:drug therapy* / Q000628:therapy; D003331:Coronary Vessels; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D013300:Streptokinase / Q000008:administration & dosage / Q000627:therapeutic use*; D015912:Thrombolytic Therapy / Q000379:methods
D013300:Streptokinase