title: Effect of genetic selection for increased body weight and sex of poult on antibody response of turkeys to Newcastle disease virus and Pasteurella multocida vaccines.
abstract: Primary and secondary antibody responses of 671 turkeys of two genetic lines to Newcastle disease virus (NDV) and Pasteurella multocida vaccines were examined. The randombred control line (RBC2) and a subline (F) of RBC2 had been selected for increased 16-week body weight. Poults were vaccinated at 6 and 12 weeks of age, and serum samples were collected 3 weeks after each vaccination. Antibody titers were determined using an enzyme-linked immunosorbent assay. Line F turkeys had significantly higher 9-week and 15-week serum antibody titers to NDV than line RBC2. However, line RBC2 had significantly higher serum antibody titers to P. multocida at 15 weeks of age than line F. The 9-week and 15-week serum antibody titers to NDV were significantly higher in females than males, but males had significantly higher 15-week serum antibody titers to P. multocida than females. Sex of poults did not contribute significantly to variation in serum antibody response to P. multocida at 9 weeks of age.
authors.affiliation: Department of Poultry Science, Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691.
authors.forename: R E
authors.initials: RE
authors.lastname: Sacco
authors.forename: K E
authors.initials: KE
authors.lastname: Nestor
authors.forename: Y M
authors.initials: YM
authors.lastname: Saif
authors.forename: H J
authors.initials: HJ
authors.lastname: Tsai
authors.forename: R A
authors.initials: RA
authors.lastname: Patterson
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D000917:Antibody Formation / Q000235:genetics*; D001428:Bacterial Vaccines / Q000276:immunology*; D001835:Body Weight; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D008297:Male; D009522:Newcastle disease virus / Q000276:immunology*; D016979:Pasteurella multocida / Q000276:immunology*; D012641:Selection, Genetic; D012727:Sex Characteristics; D013045:Species Specificity; D014422:Turkeys / Q000235:genetics / Q000276:immunology*; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000914:Antibodies, Viral; D001428:Bacterial Vaccines; D014765:Viral Vaccines