title: An interactive computer model of propagated activation with analytically defined geometry of ventricles.
abstract: A computer model of propagated activation in cardiac ventricles was developed for simulation experiments in an interactive regime on personal computers. In the model, the geometry of ventricles is defined by parts of "compound quasi-ellipsoids". The parameters specifying these ellipsoids as well as their spatial positions are derived from input data characterizing the heart geometry. Because the ventricles are defined analytically, the model renders a wide range of possibilities to vary their shape and gross dimensions. The activation is propagated from predetermined starting elements in agreement with Huygen's principle. Different propagation velocities for the myocardium and the subendocardial mesh of Purkinje fibers also may be simulated. The results of computer simulations may be evaluated both qualitatively, by isochrones of the activation propagation, and quantitatively, by the resulting cardiac vector computer in any moment of activation process.
authors.affiliation: Institute of Normal and Pathological Physiology, Slovak Academy of Sciences, Bratislava.
authors.forename: V
authors.initials: V
authors.lastname: Szathmáry
authors.forename: R
authors.initials: R
authors.lastname: Osvald
mesh_terms: D003198:Computer Simulation; D004594:Electrophysiology; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D008838:Microcomputers; D008955:Models, Cardiovascular; D012016:Reference Values; D016276:Ventricular Function / Q000502:physiology