title: Nitric oxide controls feeding behavior in the chicken.
abstract: To investigate the effect of nitric oxide (NO) on food intake in the chicken, L-NG-nitro-arginine methyl ester HCl (L-NNA), an inhibitor of NO synthase, was applied. When i.p. administered, L-NNA significantly inhibited the food intake of broiler chickens in a dose response manner. Food ingestion was also depressed by the i.c.v. injection of L-NNA in a dose response fashion. The effect of L-NNA was attenuated by i.c.v. administration of L-arginine. These results suggest that central NO may control feeding behavior in the chicken.
authors.affiliation: Laboratory of Animal Nutrition, School of Agriculture, Nagoya University, Japan.
authors.forename: Y H
authors.initials: YH
authors.lastname: Choi
authors.forename: M
authors.initials: M
authors.lastname: Furuse
authors.forename: J
authors.initials: J
authors.lastname: Okumura
authors.forename: D M
authors.initials: DM
authors.lastname: Denbow
mesh_terms: D000818:Animals; D001120:Arginine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology; D002645:Chickens; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects*; D005260:Female; D007274:Injections, Intraperitoneal; D007276:Injections, Intraventricular; D008297:Male; D009569:Nitric Oxide / Q000037:antagonists & inhibitors / Q000502:physiology*; D019335:Nitroarginine
chemical_list: D019335:Nitroarginine; D009569:Nitric Oxide; D001120:Arginine