title: Anorectal functional deficit in the Brown Bowel syndrome.
abstract: The Brown Bowel Syndrome is characterised by degeneration and pigmentation of large bowel mucosa. We present a report of this unusual syndrome in which, for the first time, a functional deficit, reflected in a reduced internal and sphincter tone, is documented. This abnormality was reversed following sub-total colectomy and vitamin E therapy.
authors.affiliation: University Department of Surgery, University College Hospital, Galway.
authors.forename: D
authors.initials: D
authors.lastname: Waldron
authors.forename: P
authors.initials: P
authors.lastname: Horgan
authors.forename: K
authors.initials: K
authors.lastname: Barry
authors.forename: J
authors.initials: J
authors.lastname: Hurley
authors.forename: H F
authors.initials: HF
authors.lastname: Given
mesh_terms: D001003:Anal Canal / Q000503:physiopathology*; D003082:Colectomy; D003108:Colonic Diseases / Q000503:physiopathology* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000503:physiopathology* / Q000628:therapy; D011312:Pressure; D012007:Rectum / Q000503:physiopathology*; D012677:Sensation / Q000502:physiology; D014810:Vitamin E / Q000097:blood / Q000627:therapeutic use
chemical_list: D014810:Vitamin E