title: Development of a high-performance multiprobe cryosurgical device.
abstract: The authors describe the design of the first multiprobe cryosurgical system (AccuProbe system). Compared with prior conventional cryosurgical devices, the new system has the following characteristics: 1) generation of subcooled liquid nitrogen, 2) optional use of up to five independently operated and controlled cryoprobes, 3) use of disposable probes of various sizes and shapes, 4) more accurate placement of the cryoprobes in the lesions due to probe miniaturization (3.4 mm in overall diameter), and 5) higher capacity freezing, which supports more accurate and controllable tissue temperatures. With the use of the newly developed system, numerous cryosurgical procedures, including those in the prostate, brain, and liver, have been successfully performed.
authors.affiliation: Cryomedical Sciences, Inc., Rockville, MD 20850.
authors.forename: Z
authors.initials: Z
authors.lastname: Chang
authors.forename: J J
authors.initials: JJ
authors.lastname: Finkelstein
authors.forename: H
authors.initials: H
authors.lastname: Ma
authors.forename: J
authors.initials: J
authors.lastname: Baust
mesh_terms: D000818:Animals; D001831:Body Temperature; D001921:Brain / Q000601:surgery; D002417:Cattle; D003080:Cold Temperature; D003452:Cryosurgery / Q000295:instrumentation*; D004209:Disposable Equipment; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D005615:Freezing; D006801:Humans; D008099:Liver / Q000601:surgery; D008107:Liver Diseases / Q000601:surgery; D008297:Male; D008904:Miniaturization; D009584:Nitrogen / Q000008:administration & dosage / Q000627:therapeutic use; D011312:Pressure; D011471:Prostatic Neoplasms / Q000601:surgery; D013499:Surface Properties
chemical_list: D009584:Nitrogen