Decreased susceptibility of melanized Cryptococcus neoformans to UV light.
Melanized Cryptococcus neoformans cells were less susceptible than nonmelanized cells to the fungicidal effects of UV light. Phenoloxidase-catalyzed production of melanin-like pigments may serve to protect the fungus against ionizing radiation.
Wang
Y
Y
Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461.
Casadevall
A
A
D003453:Cryptococcosis / Q000209:etiology; D003455:Cryptococcus neoformans / Q000378:metabolism / Q000472:pathogenicity / Q000528:radiation effects*; D006801:Humans; D008543:Melanins / Q000378:metabolism*; D008590:Meningoencephalitis / Q000209:etiology; D014466:Ultraviolet Rays
D008543:Melanins