Novel zinc chelators which inhibit the binding of HIV-EP1 (HIV enhancer binding protein) to NF-kappa B recognition sequence.
Otsuka
M
M
Institute for Chemical Research, Kyoto University, Japan.
Fujita
M
M
Sugiura
Y
Y
Ishii
S
S
Tsutomu
A
A
Yamamoto
T
T
Inoue
J I
JI
D015761:4-Aminopyridine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D001667:Binding, Competitive; D002614:Chelating Agents / Q000494:pharmacology*; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors*; D004492:Edetic Acid / Q000494:pharmacology; D016322:HIV Enhancer / Q000187:drug effects*; D006639:Histidine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008969:Molecular Sequence Data; D016328:NF-kappa B / Q000378:metabolism*; D014157:Transcription Factors; D015032:Zinc / Q000378:metabolism*
D002614:Chelating Agents; D004268:DNA-Binding Proteins; C063232:HIVEP1 protein, human; C090925:N,N'-(4-dimethylaminopyridine-2,6-diyl)-bis(histidine methyl ester); D016328:NF-kappa B; D014157:Transcription Factors; D006639:Histidine; D004247:DNA; D004492:Edetic Acid; D015761:4-Aminopyridine; D015032:Zinc