title: [Aspartate kinase complex of Anabaena variabilis during the early period of development of cyanophage A-1].
abstract: Aspartate kinase activity in cells of A. variabilis has been studied in the dynamics of development of virus infection. An early period of reproduction of cyanophage A-1 has been determined to be conjugated with the increase of biosynthesis of amino acids from aspartate family. Five isoenzymes of aspartate kinase were isolated and purified from A. variabilis cells during early development period of cyanophage A-1. Physicochemical properties and influence of amino acids of aspartate family on the activity of homogeneous isoenzymes have been studied. Retroinhibition effect was not observed in infected cyanobacteria cells, which probably enables one to increase 2-7 times the concentration of amino acids in a cell. Such an increase of the amino acids pool is apparently necessary for realization of viral genome strategy.
authors.forename: N V
authors.initials: NV
authors.lastname: Koltukova
authors.forename: G Kh
authors.initials: GKh
authors.lastname: Kadyrova
authors.forename: T G
authors.initials: TG
authors.lastname: Lysenko
authors.forename: M I
authors.initials: MI
authors.lastname: Mendzhul
mesh_terms: D001222:Aspartate Kinase / Q000737:chemistry / Q000502:physiology*; D001435:Bacteriophages / Q000502:physiology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D000458:Cyanobacteria / Q000821:virology*; D007527:Isoenzymes / Q000737:chemistry / Q000502:physiology*; D014779:Virus Replication / Q000502:physiology*
chemical_list: D007527:Isoenzymes; D001222:Aspartate Kinase
vernacular_title: Aspartatkinazynĭ kompleks Anabaena variabilis v ranniĭ period razvitiia tsianofaga A-1.