Antigenic changes in Campylobacter spp. after adaptation to media with increased sodium chloride concentrations.
Campylobacter strains which were adapted to growth at 3% NaCl in the medium were examined for antigenic changes. The results of the immunodot blot, the immunoprecipitation test and the immunoblot demonstrate changes in the antigenic pattern. Heat-labile and heat stable antigens of the obtained salt-tolerants variants of Campylobacter type-strains showed differences from their parental strains after cross-absorption of antisera. Differences of the antigens between salt-tolerant variants and their salt-sensitive parental strains suggest that the antigenic structure of the flagellum and possibly of outer membrane proteins has been changed by adaptation of strains to higher salt concentrations.
Glünder
G
G
Klinik für Geflügel, Tierärztliche Hochschule Hannover.
D000818:Animals; D000942:Antigens, Bacterial / Q000187:drug effects*; D002167:Campylobacter / Q000187:drug effects* / Q000276:immunology; D002645:Chickens; D003470:Culture Media; D015151:Immunoblotting; D005779:Immunodiffusion; D012965:Sodium Chloride / Q000494:pharmacology*; D013047:Specific Pathogen-Free Organisms
D000942:Antigens, Bacterial; D003470:Culture Media; D012965:Sodium Chloride