title: [Angioneurotic edema and anesthesia: preparation and perioperative monitoring].
abstract: Hereditary angioneurotic oedema is an autosomal dominant disease associated with serum deficiency of functional C1-inhibitor. It is characterized by periodic swelling of subcutaneous tissues, abdominal viscera and upper airways. Lethal acute episodes of oedema can occur during anaesthesia and surgery. It is essential to prepare such patients before surgery. This article describes three cases (kidney transplantation, caesarean section, normal delivery) and the various preventive measures used to avoid acute episodes during anaesthesia and surgery. Antibrinolytic agents, androgens, fresh frozen plasma, C1-inhibitor concentrate can be administered. Their various indications are discussed.
authors.affiliation: Département d'Anesthésie-Réanimation, CHU Saint-Jacques, Besançon.
authors.forename: P
authors.initials: P
authors.lastname: Koeberlé
authors.forename: C
authors.initials: C
authors.lastname: Pequenot-Jeannin
authors.forename: C
authors.initials: C
authors.lastname: Douge
authors.forename: F
authors.initials: F
authors.lastname: Barale
mesh_terms: D000328:Adult; D000768:Anesthesia, General / Q000379:methods*; D000799:Angioedema / Q000150:complications* / Q000188:drug therapy; D002585:Cesarean Section; D003174:Complement C1 Inactivator Proteins / Q000627:therapeutic use*; D003613:Danazol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D007743:Labor, Obstetric; D008297:Male; D016343:Monitoring, Intraoperative; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D011300:Preoperative Care
chemical_list: D003174:Complement C1 Inactivator Proteins; D003613:Danazol
vernacular_title: Oedème angioneurotique et anesthésie: préparation et surveillance périopératoire.