title: Warning symptoms of sinister headache.
abstract: Headache is a common complaint. In most patients, it is usually a problem of migrainous or tension-type headache. It is crucial that a physician is able to differentiate sinister causes of headache from the more benign ones. Six cases are presented to illustrate the fact that there are clues in the history to suggest a sinister cause of headache even though there are minimal or no neurological deficits on physical examination. At some point of time, these cases were examined by a senior physician but they were diagnosed as migrainous or tension-type headaches. The first case is a 41-year-old labourer with cryptococcal meningitis. He presented with severe headaches at a relatively late age. A 20-year-old female complained of the worst headache she ever had and this was due to a subarachnoid haemorrhage. The third case was a young woman with a large parietal meningioma. Her headaches had recently assumed a different character. The fourth case involved an investment manager who developed headaches with transient diplopia and projectile vomiting and investigations revealed an ependymoma. A shipyard worker complained of a constant headache which disturbed his sleep. Two weeks after medical consultation, the character of his headache changed and he developed diplopia in all directions of gaze. He succumbed to pituitary apoplexy. The final case is a 28-year-old woman who had a complicated migraine. CT scan of the brain showed a large arterio-venous malformation.
authors.affiliation: Department of Neurology, Tan Tock Seng Hospital, Singapore.
authors.forename: A K
authors.initials: AK
authors.lastname: Tan
authors.forename: Y K
authors.initials: YK
authors.lastname: Yeow
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D001165:Arteriovenous Malformations / Q000150:complications / Q000175:diagnosis; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis*; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006261:Headache / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000175:diagnosis; D008579:Meningioma / Q000150:complications / Q000175:diagnosis; D016919:Meningitis, Cryptococcal / Q000150:complications / Q000175:diagnosis; D008875:Middle Aged; D010899:Pituitary Apoplexy / Q000150:complications / Q000175:diagnosis; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000175:diagnosis