Reversible renal failure caused by a microsporidian infection.
OBJECTIVE
To report a case of renal failure associated with microsporidian infection in an HIV-seropositive patient.


METHODS
Case report.


METHODS
Chelsea and Westminster Hospital, London, England, UK.


METHODS
An HIV-seropositive patient presented febrile with abdominal pain who developed renal failure. Renal biopsy and urinalysis showed infection with a microsporidian of the genus Encephalitozoon.


METHODS
Treatment with albendazole (400 mg) twice daily was associated with disappearance of infection from the urine, clinical improvement and return of renal function virtually to normal.


CONCLUSIONS
HIV-seropositive individuals with renal failure should have urine screened for microsporidia. The administration of albendazole in such cases may reverse renal failure.
Aarons
E J
EJ
AIDS Unit, Chelsea and Westminster Hospital, London, UK.
Woodrow
D
D
Hollister
W S
WS
Canning
E U
EU
Francis
N
N
Gazzard
B G
BG
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000188:drug therapy; D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology*; D000328:Adult; D015766:Albendazole / Q000627:therapeutic use*; D000818:Animals; D001706:Biopsy; D003404:Creatinine / Q000097:blood; D016819:Encephalitozoon / Q000302:isolation & purification; D016890:Encephalitozoonosis / Q000150:complications* / Q000188:drug therapy; D006679:HIV Seropositivity; D018451:Homosexuality, Male; D006801:Humans; D007668:Kidney / Q000469:parasitology / Q000473:pathology; D008297:Male
D003404:Creatinine; D015766:Albendazole