[Is the risk of pneumocystosis predictable in Wegener's disease?].
Twelve cases of Pneumocystis pneumonia in patients with Wegener's granulomatosis were compared with a control-group of 32 patients. Our study showed that the dose of cyclophosphamide received in the first three months and a profound lymphocytopenia were strongly predictive of a risk of Pneumocystis carinii pneumonia in these patients.
Godeau
B
B
Service de médecine interne I, hôpital Henri Mondor, Créteil.
Mainardi
J L
JL
Hachulla
E
E
Guillevin
L
L
Roudot-Thoraval
F
F
Remy
P
P
Huong-Boutin
L T
LT
Schaeffer
A
A
Piette
J C
JC
D003520:Cyclophosphamide / Q000009:adverse effects; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D008231:Lymphopenia / Q000139:chemically induced; D011020:Pneumonia, Pneumocystis / Q000209:etiology* / Q000517:prevention & control; D012189:Retrospective Studies; D012307:Risk Factors
D003520:Cyclophosphamide
Le risque de pneumocystose est-il prévisible au cours de la maladie de Wegener?