title: Reproductive potential after treatment for persistent ectopic pregnancy.
abstract: We examined the success rate and reproductive outcome of 50 patients who had been treated for persistent EP after initial unsuccessful salpingostomy. All who underwent salpingectomy had successful treatment of their persistent EP. One treatment failure occurred after MTX. Of 50 women, 32 (61.5%) attempted conception after treatment for persistent EP. The cumulative clinical pregnancy rate after treatment for persistent EP was 59% at 36 months. There was a significant association between clinical pregnancy rate after persistent EP and those with normal contralateral fallopian tubes (P < 0.005). The relative risk of having a clinical pregnancy among those who attempted conception was 2.3 for those having a normal contralateral fallopian tube compared with those with a contralateral fallopian tube with obvious pathology. Intrauterine pregnancy rates after treatment of persistent EP were similar to those reported for primary treatment of EP.
authors.affiliation: Brown University School of Medicine, Providence, Rhode Island.
authors.forename: D B
authors.initials: DB
authors.lastname: Seifer
authors.forename: P D
authors.initials: PD
authors.lastname: Silva
authors.forename: D A
authors.initials: DA
authors.lastname: Grainger
authors.forename: S R
authors.initials: SR
authors.lastname: Barber
authors.forename: W D
authors.initials: WD
authors.lastname: Grant
authors.forename: J N
authors.initials: JN
authors.lastname: Gutmann
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000628:therapy*; D012098:Reproduction; D012489:Salpingostomy; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D008727:Methotrexate