title: Hemodynamic results, clinical outcome, and complications of Inoue balloon mitral valvotomy.
abstract: Percutaneous transvenous mitral commissurotomy (PTMC) was performed in 290 patients enrolled from 16 clinical centers in the United States and Canada. The mean age was 54 +/- 15 years and the mean total echocardiographic score was 7.3 +/- 2.8. Mitral valve dilatation resulted in an increase in mitral valve area from 1.0 +/- 0.3 to 1.7 +/- 0.6 cm2 (P < 0.001). Technical success, defined as final mitral area > or = 1.5 cm2 or a > or = 50% increase in area, was achieved in 83% of patients. Significant complications included mitral valve replacement in the hospital 1.0% and hospital death in 1.4%. Failure to cross the mitral valve occurred in 1.7%. Other complications that did not interfere with discharge from the hospital with a completed PTMC procedure occurred in 12.1% of patients. Among patients with successful PTMC, the valve area remained constant over a 24-month follow-up period. Although a minority of patients were NYHA Class I or II prior to PTMC, > 80% remained in Class I or II throughout the 2-yr follow-up period. The overall results in this registry demonstrate that the acute hemodynamic results of the procedure are excellent, the incidence of procedure related complications is acceptable, and a majority of patients remain symptomatically improved during a 2-yr follow-up period.
authors.affiliation: Hans Hecht Hemodynamics Laboratory, Pritzker School of Medicine, University of Chicago Hospitals, Illinois 60637.
authors.forename: T
authors.initials: T
authors.lastname: Feldman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002404:Catheterization / Q000295:instrumentation* / Q000379:methods / Q000401:mortality; D016009:Chi-Square Distribution; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D015337:Multicenter Studies as Topic; D012042:Registries; D017741:Survivors; D016896:Treatment Outcome