title: [Skin reactions attributed to the use of bromhexine].
abstract: Since 1972, the Netherlands Centre for Monitoring of Adverse Reactions to Drugs has received 22 reports of skin reactions attributed to use of bromhexine. The reports concerned II men and II women. The ages ranged between 5 months and 88 years. The skin reactions occurred within one to 30 days after starting the use of bromhexine. Most skin reactions consisted of generalised urticaria. Other reports concerned once an angioedema and once an anaphylactic reaction. Most patients recovered completely after cessation of bromhexine without further treatment.
authors.affiliation: Afd. Farmaco-epidemiologie en Farmacotherapie, Bureau Bijwerkingen Geneesmiddelen, Rijswijk.
authors.forename: M M
authors.initials: MM
authors.lastname: van Riemsdijk
authors.forename: M M
authors.initials: MM
authors.lastname: van der Klauw
authors.forename: B H
authors.initials: BH
authors.lastname: Stricker
authors.forename: R M
authors.initials: RM
authors.lastname: Herings
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000707:Anaphylaxis / Q000139:chemically induced; D001964:Bromhexine / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced; D006969:Hypersensitivity, Immediate / Q000139:chemically induced; D007223:Infant; D008297:Male; D008875:Middle Aged
chemical_list: D001964:Bromhexine
vernacular_title: Huidreacties toegeschreven aan het gebruik van broomhexine.