title: Changes in urinary kallikrein excretion and plasma natriuretic factor in a patient with primary aldosteronism with special reference to adrenal histology.
abstract: High level of urinary kallikrein excretion was observed in a 23-year-old man with primary aldosteronism. Unilateral adrenalectomy improved the clinical symptoms and normalized the urinary concentration of this vasoactive substance. Although plasma atrial natriuretic factor was not elevated, adrenal surgery lowered its concentration. Coexistence of an adrenal adenoma and lesions of nodular hyperplasia were detected in the removed adrenal gland. We summarize the clinical data of this patient and review the literature.
authors.affiliation: Department of Urology, Yamagata University, School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hayami
authors.forename: T
authors.initials: T
authors.lastname: Nakada
authors.forename: H
authors.initials: H
authors.lastname: Kakizaki
authors.forename: T
authors.initials: T
authors.lastname: Yagisawa
authors.forename: H
authors.initials: H
authors.lastname: Kaneko
authors.forename: Y
authors.initials: Y
authors.lastname: Iijima
authors.forename: H
authors.initials: H
authors.lastname: Obata
authors.forename: M
authors.initials: M
authors.lastname: Miura
mesh_terms: D000302:Adrenal Cortex / Q000473:pathology*; D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D000315:Adrenalectomy; D018246:Adrenocortical Adenoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D000328:Adult; D009320:Atrial Natriuretic Factor / Q000097:blood*; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology / Q000378:metabolism*; D007610:Kallikreins / Q000652:urine*; D008297:Male
chemical_list: D009320:Atrial Natriuretic Factor; D007610:Kallikreins