title: [Serum E2 and progesterone levels in patients with atypical hyperplasia and endometrial carcinoma].
abstract: The authors study the serum levels of E2 and progesterone in 62 women with endometrial cancer and in 16 with atypical hyperplasia. Twenty women in a premenopausal phase have been used as a control group. In the patients with AH and EC normo or hypoestradiolaemia have been found. A marked hypoprogesteronaemia has been observed, which is expressed mainly in patients with AH. The low concentrations of progesterone in patients in pre- and postmenopausal phase are important markers for increased morbidity. The study of the progesterone level should become a routine method in the group with high risk of development of endometrial cancer.
authors.forename: G
authors.initials: G
authors.lastname: Gorchev
authors.forename: A
authors.initials: A
authors.lastname: Maleeva
mesh_terms: D002277:Carcinoma / Q000097:blood*; D004714:Endometrial Hyperplasia / Q000097:blood*; D016889:Endometrial Neoplasms / Q000097:blood*; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000097:blood; D017697:Premenopause / Q000097:blood; D011374:Progesterone / Q000097:blood*; D011863:Radioimmunoassay
chemical_list: D011374:Progesterone; D004958:Estradiol
vernacular_title: Prouchvane na serumnite niva na E2 i progesterona pri bolni s atipichna khiperplaziia i endometrialen kartsinom.