title: [The behavior and utility of 3-methylhistidine, urinary urea excretion and the creatinine height index in the sepsis patient].
abstract: We have studied in a prospective manner the evolution of three urinary indices which measure protein catabolism: 3-methylhistidine, the creatinine level index, and the excretion of urinary nitrogen, the latter being calculated based on the excretion of urea in urine. These studies have been performed using healthy patients only being given parenteral nutrition. Our data shows a very significant decrease in 3-methylhistidine (p = 0.001) and in the excretion of nitrogen calculated (p = 0.026), there being a correlation among the differences between these two parameters.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Universitario Virgen del Rocío, Sevilla, España.
authors.forename: J
authors.initials: J
authors.lastname: Garnacho Montero
authors.forename: C
authors.initials: C
authors.lastname: Ortiz Leyba
authors.forename: F J
authors.initials: FJ
authors.lastname: Jiménez Jiménez
authors.forename: F
authors.initials: F
authors.lastname: Gayoso
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000652:urine; D003404:Creatinine / Q000652:urine*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008762:Methylhistidines / Q000652:urine*; D008875:Middle Aged; D009584:Nitrogen / Q000652:urine; D010288:Parenteral Nutrition; D011446:Prospective Studies; D018805:Sepsis / Q000628:therapy / Q000652:urine*; D014508:Urea / Q000652:urine*
chemical_list: D015415:Biomarkers; D008762:Methylhistidines; D014508:Urea; D003404:Creatinine; C028118:3-methylhistidine; D009584:Nitrogen
vernacular_title: Comportamiento y utilidad de 3-metilhistidina, excreción de urea urinaria e índice creatinina-altura en el paciente con sepsis.