title: Disorders of the central nervous system.
abstract: In this article, we have reviewed the most common CNS abnormalities seen in perinatal medicine. The prognosis in ventriculomegaly is most closely related to the presence or absence of associated anomalies. The current treatment for DWM consists of shunting of either the posterior fossa cyst or lateral ventricles. Facial abnormalities can frequently aid in distinguishing holoprosencephaly from other CNS lesions. Anencephaly is one of the most severe fetal anomalies and is incompatible with life. Spina bifida represents a spectrum of NTDs with a variable outcome depending on the size and location of the defect, as well as the presence of other anomalies.
authors.affiliation: Department of Obstetrics and Gynecology, Tufts University School of Medicine, Boston, MA 02111.
authors.forename: M J
authors.initials: MJ
authors.lastname: Paidas
authors.forename: A
authors.initials: A
authors.lastname: Cohen
mesh_terms: D002493:Central Nervous System Diseases / Q000000981:diagnostic imaging* / Q000196:embryology / Q000628:therapy; D003616:Dandy-Walker Syndrome / Q000000981:diagnostic imaging / Q000196:embryology / Q000628:therapy; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000628:therapy; D016142:Holoprosencephaly / Q000000981:diagnostic imaging / Q000196:embryology / Q000628:therapy; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000196:embryology / Q000628:therapy; D009436:Neural Tube Defects / Q000000981:diagnostic imaging / Q000196:embryology / Q000628:therapy; D011247:Pregnancy; D016216:Ultrasonography, Prenatal