[Genetic control of yeast cell morphology].
Yeast cell phenotype and morphology result from the interaction of two processes, polarized growth, on the one hand, and cytokinesis with subsequent division of the cell wall, on the other. Imbalance of the equilibrium of these two principal processes may lead to the occurrence of yeast morphological mutants that generate rough colonies. Two types of such mutants exist, Rgh and Rpm. The Rgh mutants have ellipsoid cells and either form chains or generate clumps at high frequency. These changes in heterothallic strains of saccharomyces occur due to recessive mutations in any of 11 non-linked genes. In homothallic strains of saccharomyces, the trait Rgh depends on the complementary interaction of one dominant and two recessive genes. Rpm mutants generate rough colonies, which contain elongated cells that give rise to pseudomycelium. The mutants obtained are recessive and occur in six non-linked genes. The Rpm mutants represent an example of the manifestation of mycelium-yeast dimorphism in fungi, and this case may be regarded as a simple morphogenetic model.
Egorova
V N
VN
Lakhchev
K L
KL
D002455:Cell Division / Q000235:genetics; D009154:Mutation; D010641:Phenotype; D012440:Saccharomyces / Q000235:genetics; D015003:Yeasts / Q000235:genetics* / Q000254:growth & development / Q000648:ultrastructure
Geneticheskiĭ kontrol' morfologii drozhzhevoĭ kletki.