title: Supraventricular tachyarrhythmia associated with baclofen overdose.
abstract: Baclofen overdose occasionally results in cardiac effects, but serious tachyarrhythmias have not been reported. We present the case of a 21-year-old man with an acute baclofen overdose who developed increased cardiac conduction times and a rapid supraventricular tachyarrhythmia which required medical intervention. Acute baclofen toxicity can result in the development of tachyarrhythmias and cardiac monitoring is warranted in acute overdose states.
authors.affiliation: University of Pittsburgh Medical Center, PA 15213.
authors.forename: R J
authors.initials: RJ
authors.lastname: Roberge
authors.forename: T G
authors.initials: TG
authors.lastname: Martin
authors.forename: M
authors.initials: M
authors.lastname: Hodgman
authors.forename: J G
authors.initials: JG
authors.lastname: Benitez
authors.forename: J E
authors.initials: JE
authors.lastname: Brunswick
mesh_terms: D000241:Adenosine / Q000627:therapeutic use; D000328:Adult; D001418:Baclofen / Q000037:antagonists & inhibitors / Q000506:poisoning*; D062787:Drug Overdose / Q000150:complications / Q000503:physiopathology; D004562:Electrocardiography / Q000187:drug effects; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D013406:Suicide, Attempted; D013617:Tachycardia, Supraventricular / Q000139:chemically induced* / Q000503:physiopathology; D014700:Verapamil / Q000627:therapeutic use
chemical_list: D014700:Verapamil; D001418:Baclofen; D000241:Adenosine