Release of an alkylating metabolite, dehydromonocrotaline, from the isolated liver perfused with the pyrrolizidine alkaloid, monocrotaline.
Yan
C C
CC
Department of Pharmacology, University of Arizona College of Medicine, Tucson 85724.
Huxtable
R J
RJ
D000477:Alkylating Agents / Q000493:pharmacokinetics*; D000818:Animals; D001646:Bile / Q000737:chemistry / Q000378:metabolism; D002855:Chromatography, Thin Layer; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism*; D016686:Monocrotaline / Q000031:analogs & derivatives / Q000493:pharmacokinetics*; D010477:Perfusion; D051381:Rats
D000477:Alkylating Agents; C014114:monocrotaline pyrrole; D016686:Monocrotaline