title: Aspergillosis of the larynx.
abstract: Primary infection of the larynx with Aspergillus spp. is rare. It is more commonly seen as part of a wider infection involving the respiratory system in an immunocompromised host. In noncompromised patients laryngeal aspergillosis may represent colonization rather than invasion requiring no systemic anti-fungal treatment. The diagnosis is important as the presenting symptoms are suggestive of malignant laryngeal disease. We present a 62-year-old man with a short history of hoarseness. Direct laryngoscopy and biopsy confirmed the diagnosis of aspergillosis. Clinical presentation, diagnosis and the important pathological characteristics of this infection are discussed.
authors.affiliation: Royal National Throat, Nose and Ear Hospital, London.
authors.forename: R
authors.initials: R
authors.lastname: Benson-Mitchell
authors.forename: N
authors.initials: N
authors.lastname: Tolley
authors.forename: C B
authors.initials: CB
authors.lastname: Croft
authors.forename: A
authors.initials: A
authors.lastname: Gallimore
mesh_terms: D001228:Aspergillosis / Q000175:diagnosis*; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000382:microbiology; D007830:Larynx / Q000382:microbiology; D008297:Male; D008875:Middle Aged