[Congenital deficiency of protein C with late clinical manifestation].
The congenital deficit of protein C has a great diversity of clinical manifestations regarding age. In this paper, we describe the case of a man whose initial symptomatology appeared at the age of 68. Protein C is a vitamin-K dependent plasmatic glycoprotein which has anticoagulant activity through the inactivation of factors Va and VIIIa. The hereditary deficit of protein C is usually presented in a dominant autosomic mode with partial penetration and its prevalence is estimated in each of 200-300 healthy blood donors.
Ortega Calvo
M
M
Centro de Salud Virgen de Belén, Pilas.
Méndez Mora
J L
JL
Macías Pérez
V
V
Mellado Fuentes
F
F
D000368:Aged; D006801:Humans; D008297:Male; D008661:Metabolism, Inborn Errors / Q000175:diagnosis*; D020151:Protein C Deficiency; D013997:Time Factors
Déficit congénito de proteína C con expresión clínica tardía.