title: The "brave new world" of transmissible spongiform encephalopathy (infectious cerebral amyloidosis).
abstract: The story of transmissible human spongiform encephalopathy, from its origins to the present time, enjoys the commentary of a cast of characters from Shakespeare's imaginary island in The Tempest, with a brief visit to the real island of Tasmania for a bird's eye view of the prion, and some concluding thoughts about the current state of research in the netherworlds of molecular biology and physical chemistry.
authors.affiliation: Laboratory of CNS Studies, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
authors.forename: P
authors.initials: P
authors.lastname: Brown
mesh_terms: D000818:Animals; D001717:Birds; D049711:History, Modern 1601-; D006801:Humans; D017096:Prion Diseases / Q000266:history / Q000503:physiopathology*; D011328:Prions / Q000737:chemistry; D017433:Protein Structure, Secondary; D013648:Tasmania
chemical_list: D011328:Prions