[Are we typing HLA-A, B, and C antigens correctly?].
Analysis of the results of check-up examinations of HLA-A,B,C antigens in 62 cases of paternity demonstrated complete agreement of the first and second expert in 58.06% cases. Differences in 26 cases (= 41.94%) consisted in 10 cases in the detection of different HLA antigens from the first and second expert (owing in 6 cases to the different conclusion of the experts' account) and in 16 cases in the evidence of some HLA antigen only from one expert (usually by the revision). The most frequent errors pertained to the evidence of HLA antigens A28, A29, A30/31, A33, B16, B17, B21, B18, Bw22 and of the antigens of HLA-C locus; however, the well demonstrable HLA antigens A9, A10, B8, B13 were also not proved. The causes of the mistakes were analysed. It is necessary to avoid the errors of the administrative character and by the evaluation of the results in doubtful cases.
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Ustav hematologie a krevní transfúze, Praha.
D003951:Diagnostic Errors; D005260:Female; D015234:HLA-A Antigens / Q000032:analysis; D015235:HLA-B Antigens / Q000032:analysis; D015236:HLA-C Antigens / Q000032:analysis; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D010334:Paternity
D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens
Typujeme dobre HLA-A,B,C antigeny?