title: Ibuprofen overdose complicated by renal failure, adult respiratory distress syndrome, and metabolic acidosis.
abstract: Acute ingestion of ibuprofen commonly results in no symptoms, or minor gastrointestinal or central nervous system manifestations. While most cases of ibuprofen overdose do well, serious toxicity may occur, and is difficult to predict. A case of ibuprofen overdose is presented in which the course was complicated by metabolic acidosis, adult respiratory distress syndrome, and renal failure necessitating prolonged dialysis.
authors.affiliation: University of Louisville School of Medicine, Department of Emergency Medicine, KY 40292.
authors.forename: H T
authors.initials: HT
authors.lastname: Le
authors.forename: G M
authors.initials: GM
authors.lastname: Bosse
authors.forename: Y
authors.initials: Y
authors.lastname: Tsai
mesh_terms: D000138:Acidosis / Q000139:chemically induced* / Q000150:complications; D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000150:complications / Q000628:therapy; D000328:Adult; D002606:Charcoal / Q000627:therapeutic use; D002951:Citrates / Q000627:therapeutic use; D019343:Citric Acid; D062787:Drug Overdose; D006801:Humans; D007052:Ibuprofen / Q000506:poisoning*; D008297:Male; D009846:Oliguria / Q000139:chemically induced* / Q000150:complications / Q000628:therapy; D006435:Renal Dialysis; D012128:Respiratory Distress Syndrome / Q000139:chemically induced* / Q000150:complications / Q000628:therapy; D013406:Suicide, Attempted
chemical_list: D002951:Citrates; D002606:Charcoal; D019343:Citric Acid; D007052:Ibuprofen