title: Quantitative analysis of seizure frequency 1 week and 6, 12, and 24 months after surgery of epilepsy.
abstract: We made quantitative analysis of seizure frequency 1 week and 6, 12, and 24 months after seizure surgery. Seizure recurrence was significantly higher when seizures occurred in the first postoperative week. Seizure recurrence increased progressively with longer follow-ups, but the 6 month postoperative follow-up period was an excellent index of long-term outcome. In operative follow-up studies, seizure frequency should be reported at fixed follow-up periods, e.g., at 6 months and 1, 2, 5, and 10 years. Meaningful comparison of outcomes between different studies is possible only when reports include outcome at fixed postoperative follow-up periods (as opposed to ranges of follow-up periods).
authors.affiliation: Cleveland Clinic Epilepsy Program, Cleveland Clinic Foundation, OH 44195-5226.
authors.forename: H
authors.initials: H
authors.lastname: Lüders
authors.forename: D
authors.initials: D
authors.lastname: Murphy
authors.forename: I
authors.initials: I
authors.lastname: Awad
authors.forename: E
authors.initials: E
authors.lastname: Wyllie
authors.forename: D S
authors.initials: DS
authors.lastname: Dinner
authors.forename: H H
authors.initials: HH
authors.lastname: Morris
authors.forename: A D
authors.initials: AD
authors.lastname: Rothner
mesh_terms: D016009:Chi-Square Distribution; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011184:Postoperative Period; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome