title: Otitis media: microbiology and management.
abstract: Otitis media (OM) is a common childhood disease and one that can cause significant morbidity. A knowledge of the pathogens responsible for OM can assist in the selection of the most appropriate treatment regimen and can minimize complications that may require surgery. The microbiology of acute, serous, and chronic OM is reviewed. The major organisms recovered from about three quarters of acute OM and half of serous OM cultures are Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis. Streptococcus pyogenes, anaerobic cocci, and viruses can each be isolated in less than 5% of the patients with acute OM. The predominant organisms isolated from chronic OM are Staphylococcus aureus, Pseudomonas aeruginosa, and anaerobic bacteria. The predominant anaerobes are gram-positive cocci, pigmented Prevotella and Porphyromonas sp, Bacteroides sp, and Fusobacterium sp. Many of the aerobic and anaerobic organisms causing OM can produce beta-lactamase, rendering them resistant to many of the penicillins. The appropriate surgical and medical therapies for acute, serous, and chronic otitis media are discussed.
authors.affiliation: Department of Pediatrics, Georgetown University School of Medicine, Washington, District of Columbia.
authors.forename: I
authors.initials: I
authors.lastname: Brook
mesh_terms: D002648:Child; D002675:Child, Preschool; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D010033:Otitis Media / Q000382:microbiology* / Q000628:therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013296:Streptococcus pneumoniae / Q000302:isolation & purification