title: Effects of passive and active smoking on induction of anaesthesia.
abstract: It is said that cigarette smokers suffer stormy induction of anaesthesia; although plausible, this is unsubstantiated. We have studied the incidence of adverse events during induction, together with peripheral oxygen saturation (SpO2), in active and passive smokers, and in non-smokers. During induction, both active and passive smokers had a higher incidence of adverse events than non-smokers (P < 0.01 and P < 0.05, respectively). Irrespective of smoking status, those suffering adverse events had greater concentrations of carboxyhaemoglobin and suffered more oxygen desaturation than those not suffering such events. Although we were unable to demonstrate a direct link between smoking status and oxygen desaturation during induction, our study gives a firmer basis for exhorting patients not only to stop smoking before anaesthesia but also to avoid passive smoking.
authors.affiliation: Department of Anaesthesia, City Hospital, Nottingham.
authors.forename: A
authors.initials: A
authors.lastname: Dennis
authors.forename: J
authors.initials: J
authors.lastname: Curran
authors.forename: J
authors.initials: J
authors.lastname: Sherriff
authors.forename: W
authors.initials: W
authors.lastname: Kinnear
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000009:adverse effects*; D002263:Carboxyhemoglobin / Q000032:analysis; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D012120:Respiration Disorders / Q000097:blood / Q000209:etiology*; D012907:Smoking / Q000009:adverse effects*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
chemical_list: D014028:Tobacco Smoke Pollution; D002263:Carboxyhemoglobin; D010100:Oxygen