title: [Use of levamisole electrophoresis in chemical prophylaxis in adolescents with a change in tuberculin reaction].
abstract: Immunological reactivity was assessed in 108 adolescents aged 12-17: 25 healthy subjects, 29 and 54 adolescents with a turn in tuberculin tests. The latter received isoniazid alone for 3 months and in combination with levamisole electrophoresis, respectively. Immunological reactivity responded more advantageously in 54 subjects exposed to adjuvant levamisole electrophoresis. They showed inhibition of immunospecific reactions and enhancement of nonspecific ones as well as of skin tuberculin sensitivity. Levamisole electrophoresis raised the efficacy of secondary prophylaxis in adolescents with a turn in tuberculin tests.
authors.forename: I A
authors.initials: IA
authors.lastname: Sirenko
authors.forename: P N
authors.initials: PN
authors.lastname: Nastas
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D007478:Iontophoresis; D007538:Isoniazid / Q000627:therapeutic use; D007978:Levamisole / Q000008:administration & dosage*; D008297:Male; D013997:Time Factors; D014373:Tuberculin / Q000276:immunology; D014374:Tuberculin Test; D014397:Tuberculosis, Pulmonary / Q000517:prevention & control*
chemical_list: D014373:Tuberculin; D007978:Levamisole; D007538:Isoniazid
vernacular_title: Primenenie élektroforeza levamizola pri khimmioprofilaktike u podrostkov s virazhom tuberkulinovykh reaktsiĭ.