title: [Ion generators and bronchial asthma. A double-blind placebo controlled study].
abstract: In this double blind, placebo-controlled study we examined the value of using a device for ionizing the air in the immediate environment as a therapy for asthma bronchiale. Nineteen adult patients with stable, reversible asthma were randomised to blind treatment with either an active device or an inactive placebo-device. After four weeks treatment the patients were given the alternative device for another period of four weeks. We measured daily peak-flow, symptomscore, use of medicine and spirometry and found no differences between the two periods. Therapy with ionization of the environmental air in patients with bronchial asthma should not be recommended.
authors.affiliation: Medicinsk/lungemedicinsk afdeling Y, Amtssygehuset i Gentofte.
authors.forename: K R
authors.initials: KR
authors.lastname: Larsen
authors.forename: O T
authors.initials: OT
authors.lastname: Olsen
authors.forename: I L
authors.initials: IL
authors.lastname: Jarnvig
authors.forename: U G
authors.initials: UG
authors.lastname: Svendsen
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000328:Adult; D000390:Air Ionization; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D010919:Placebos
chemical_list: D001993:Bronchodilator Agents; D010919:Placebos
vernacular_title: Iongeneratorer og asthma bronchiale. En dobbeltblind placebokontrolleret undersøgelse.