[A clinical and experimental study of the role of long-lasting perioperative epidural anesthesia in the prevention of phantom limb pain].
The aim of this study was to investigate the possible onset of phantom limb pain (PLP) and its development depending on preoperative limb pain and type of anesthesia during limb amputation. It was experimentally proved that preliminary local anesthesia of rat sciatic nerve slowed down the development of pain syndrome after the operation as well as reduced the number of rats with pain syndrome, as compared to the group subjected to preliminary painful electrical stimulation of the operated on limb. The clinical data presented reveal a significant reduction in the incidence of PLP after perioperative epidural anesthesia, as compared to patients with preoperative pain operated on under general anesthesia.
Ovechkin
A M
AM
Kukushkin
M L
ML
Gnezdilov
A V
AV
Reshetniak
V K
VK
D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D000767:Anesthesia, Epidural; D000768:Anesthesia, General; D000772:Anesthesia, Local; D000818:Animals; D004558:Electric Stimulation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000517:prevention & control*; D010591:Phantom Limb; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve; D013577:Syndrome
Kliniko-éksperimental'noe issledovanie roli dlitel'noĭ perioperatsionnoĭ épidural'noĭ anestezii v profilaktike fantomno-bolevogo sindroma.