Sex steroid hormones and cell dynamics in the periodontium.
The biological changes that occur in tissues of the periodontium during puberty, the menstrual cycle, pregnancy, menopause, and oral contraceptive use have heightened interest in the relationship between sex steroid hormones and periodontal health. These clinical observations coupled with tissue specificity of hormone localization, identification of hormone receptors, as well as the metabolism of hormones have strongly suggested that periodontal tissues are targets for androgens, estrogens, and progestins. The etiologies of periodontal endocrinopathies are diverse; nonetheless, periodontal pathologies may be a consequence of the actions and interactions of sex steroid hormones on specific cells found in the periodontium.
Mariotti
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Department of Periodontology and Pharmacology, J. Hillis Miller Health Science Center, University of Florida, Gainesville 32610.
D003276:Contraceptives, Oral / Q000494:pharmacology; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006801:Humans; D008297:Male; D008593:Menopause / Q000502:physiology; D008597:Menstrual Cycle / Q000502:physiology; D010510:Periodontal Diseases / Q000209:etiology; D010519:Periodontium / Q000166:cytology*; D011247:Pregnancy; D011627:Puberty / Q000502:physiology; D011987:Receptors, Steroid / Q000187:drug effects / Q000502:physiology
D003276:Contraceptives, Oral; D012739:Gonadal Steroid Hormones; D011987:Receptors, Steroid