[Bacterial endotoxins: a pathogenic factor in asthma?].
Though the house dust mite allergen is considered as one of the most important factors in perennial asthma, several observations suggest that it could be but one of several factors leading to asthma. Exposure to bacterial endotoxins has been associated with some occupational chronic obstructive bronchial diseases. In the present work, endotoxins were measured in the house dust, and observations of the skin and bronchial challenge tests as well epidemiological studies suggest that they play a role in asthma.
Michel
O
O
Clinique de Pneumologie, Hôpital Saint-Pierre, Bruxelles.
D000053:Acari / Q000276:immunology; D000818:Animals; D001249:Asthma / Q000139:chemically induced* / Q000276:immunology; D001985:Bronchial Provocation Tests; D004391:Dust / Q000009:adverse effects; D004731:Endotoxins / Q000009:adverse effects*; D006801:Humans; D008070:Lipopolysaccharides / Q000009:adverse effects; D008173:Lung Diseases, Obstructive / Q000139:chemically induced
D004391:Dust; D004731:Endotoxins; D008070:Lipopolysaccharides
Les endotoxines bactériennes: un facteur pathogène de l'asthme?