title: [Parasitologic and serological evaluation of caprines experimentally inoculated with Trypanosoma cruzi].
abstract: The experimental infection by Trypanosoma cruzi was studied in nine young goats. These animals were inoculated by intraperitoneal route with 10(3) trypomastigotes/Kg body weight with strains 147 (Group 1) and 229 (Group 2), isolated from chronic Chagasic patients proceeding from Bambuí, Minas Gerais, Brazil. The infected animals were submitted to fresh blood examinations, xenodiagnosis, hemoculture and serology (IFAT and ELISA). The follow up of T. cruzi infection ranged from 7 to 30 months and it was possible to note a markable difference concerning the course of infection between the two groups. The parasite was visualized, for the first time in experimentally infected goats in the acute period through fresh blood examinations and xenodiagnosis and through hemoculture and xenodiagnosis during the chronic period of the Chagasic infection. These results suggest that, under some epidemiological conditions, goats may be important in the sylvatic and peridomiciliar transmission cycles of T. cruzi specially young animals.
authors.affiliation: Posto Avançado de Estudos Emmanuel Dias, Laboratório de Biologia de Triatomineos e Epidemiologia da doença de Chagas, Centro de Pesquisas René Rachou, Belo Horizonte, MG, Brasil.
authors.forename: A J
authors.initials: AJ
authors.lastname: Fernandes
authors.forename: R W
authors.initials: RW
authors.lastname: Vitor
authors.forename: J C
authors.initials: JC
authors.lastname: Dias
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D014355:Chagas Disease / Q000097:blood / Q000276:immunology / Q000662:veterinary*; D015511:Goat Diseases / Q000097:blood / Q000276:immunology / Q000469:parasitology*; D006041:Goats / Q000097:blood / Q000276:immunology* / Q000469:parasitology; D014349:Trypanosoma cruzi / Q000276:immunology*
chemical_list: D000913:Antibodies, Protozoan
vernacular_title: Avaliação parasitológica e sorológica de caprinos inoculados experimentalmente pelo Trypanosoma cruzi.