[Role of antioxidant enzymes of the fetoplacental complex in neonatal adaptation to maternal diabetes mellitus].
Instability of the system of detoxication of peroxidative products and system of generation of free-radical oxidation of membrane lipids in placenta, funic blood, in amniotic water of mothers with diabetes mellitus and in newborns blood has been found. It is shown, that the exhaustion of antioxidative status of fetoplacental complex connected with the depression of antioxidative activity in blood of the newborns reflects the frustration of adaptation reaction of the newborn's organism, that may increase the risk of perinatal diseases or mortality.
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D000222:Adaptation, Physiological; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D002570:Ceruloplasmin / Q000378:metabolism; D005314:Embryonic and Fetal Development / Q000502:physiology; D005260:Female; D005982:Glutathione Transferase / Q000378:metabolism; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000201:enzymology*; D011379:Prognosis; D013482:Superoxide Dismutase / Q000378:metabolism
D000975:Antioxidants; D002374:Catalase; D013482:Superoxide Dismutase; D002570:Ceruloplasmin; D005982:Glutathione Transferase
Rol' antioksidantnykh fermentov fetoplatsentarnogo kompleksa v adaptatsii novorozhdennykh pri sakharnom diabete u matereĭ.