title: [Kidney involvement in idiopathic myelofibrosis].
abstract: Functional potential of the kidneys, principal causes of nephrolithiasis and chronic renal failure were investigated in 30 idiopathic myelofibrosis (IMF) patients by combination of different modalities, sonography, in particular. Sonography proved highly informative in diagnosis of nephroliths the formation of which is attributed to derangement of uric acid metabolism, of renal elimination, and anatomical features of the urinary system. A correlation analysis between various factors showed that in IMF hyperuricemia, hyperfiltration and proteinuria damage cortical and medullary layers of the kidneys provoking their functional defects and development of chronic renal failure.
authors.forename: S S
authors.initials: SS
authors.lastname: Bessmel'tsev
authors.forename: K M
authors.initials: KM
authors.lastname: Abdulkadyrov
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology; D007669:Kidney Calculi / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D011507:Proteinuria / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D014463:Ultrasonography
vernacular_title: Porazhenie pochek pri idiopaticheskom mielofibroze.