title: Cisapride.
abstract: Renal patients often complain of vague abdominal symptoms compatible with a gastric motility disorder. Cisapride is a recently available prokinetic agent that improves motility and emptying of the upper gastrointestinal tract in patients on long-term dialysis. The drug is extensively metabolized in the liver producing metabolites with minimal pharmacologic activity. Adverse reactions are primarily gastrointestinal in nature and include abdominal cramps, flatulence, and diarrhea.
authors.forename: P M
authors.initials: PM
authors.lastname: Hubbard
mesh_terms: D020117:Cisapride; D005764:Gastroesophageal Reflux / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D010880:Piperidines / Q000494:pharmacology / Q000627:therapeutic use*; D006435:Renal Dialysis; D051437:Renal Insufficiency / Q000150:complications*
chemical_list: D010880:Piperidines; D020117:Cisapride