[Course of infiltrating pulmonary tuberculosis depending on the patient's genotype].
To compare the disease course with regard to genetic markers carriage, the authors have examined 84 tuberculous patients. It was established that carriers of antigen HLA-DR2 and haptoglobin phenotype 2-2 have large cavities of destruction and more advanced dissemination. This trend is more evident in combination of above markers. These carriers are also noted to exhibit less advantageous run of pulmonary tuberculosis as shown by longer terms of the bacterial isolation and cavern healing.
Fedoseeva
S V
SV
Iusopova
M M
MM
Chukanova
V P
VP
Pospelov
L E
LE
D000328:Adult; D005260:Female; D005819:Genetic Markers; D005838:Genotype; D006684:HLA-DR Antigens / Q000032:analysis; D006242:Haptoglobins / Q000235:genetics; D006801:Humans; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000235:genetics*
D005819:Genetic Markers; D006684:HLA-DR Antigens; D006242:Haptoglobins
Techenie infil'trativnogo tuberkuleza legkikh v zavisimosti ot genotipa bol'nogo.