title: Kinocilia in the developing stria vascularis of the rat pup.
abstract: The mammalian stria vascularis undergoes certain developmental changes in the postnatal rat. The present study was designed to examine the ultrastructure of the stria vascularis in rat pups from immediately after birth to 20 days postpartum. The cochlea were removed with the animals under xylazine (Rompun) anesthesia and were prepared for transmission electron microscopy. Each of the three cell types in the stria were found to contain kinocilia up until 12-17 days of age. The presence of kinocilia in the intermediate and basal cells has not been previously described. Findings suggest that these organelles may serve a motile and/or sensory function to assist in the maturation of cell functions, particularly ion transport, during early stages of development.
authors.affiliation: Department of Surgery, Southern Illinois University School of Medicine, Springfield 62794-9230.
authors.forename: C
authors.initials: C
authors.lastname: Whitworth
authors.forename: A
authors.initials: A
authors.lastname: Weberg
authors.forename: D
authors.initials: D
authors.lastname: Wagahoff
authors.forename: L P
authors.initials: LP
authors.lastname: Rybak
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn / Q000033:anatomy & histology; D008854:Microscopy, Electron; D015388:Organelles / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley; D013316:Stria Vascularis / Q000648:ultrastructure*