title: Histopathological characterization of photochemical damage in nervous tissue.
abstract: This paper discusses histological and ultrastructural changes produced by dye-sensitized photoreactions in the central and peripheral nervous system. Particular attention has been given to morphological outcome in experimental models which reproduce widespread clinical pathologies, e.g. stroke, spinal cord injury and peripheral neuropathy. Evaluation of structural alterations may not only help to characterize the evolution of these disease processes but also allow us to study possibilities of therapeutic intervention.
authors.affiliation: Department of Morphology, Life Sciences, Janssen Research Foundation, Beerse, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Van Reempts
authors.forename: M
authors.initials: M
authors.lastname: Borgers
mesh_terms: D000818:Animals; D002561:Cerebrovascular Disorders / Q000473:pathology; D004195:Disease Models, Animal; D008027:Light; D009420:Nervous System / Q000473:pathology* / Q000528:radiation effects* / Q000648:ultrastructure; D011838:Radiation-Sensitizing Agents; D013119:Spinal Cord Injuries / Q000473:pathology
chemical_list: D011838:Radiation-Sensitizing Agents