title: The gene for the familial form of incontinentia pigmenti (IP2) maps to the distal part of Xq28.
abstract: Linkage data for familial incontinentia pigmenti (IP2) and 17 X chromosomal markers are reported. The linkage previously found between IP2 and the F8C locus is confirmed (Z max = 11.85 at theta = 0.028). Linkage is established with distal markers DXS1108 (Z max = 10.06 at theta = 0.00) and DXYS154 (Z = 9.07 at theta = 0.019). Multipoint analysis supports the distal localization of the IP2 gene with respect to the F8C locus.
authors.affiliation: Unité de Recherches sur les Handicaps Génétiquesde l'Enfant, INSERM U. 12, Hôpital Necker-Enfants Malades, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Smahi
authors.forename: C
authors.initials: C
authors.lastname: Hyden-Granskog
authors.forename: B
authors.initials: B
authors.lastname: Peterlin
authors.forename: P
authors.initials: P
authors.lastname: Vabres
authors.forename: S
authors.initials: S
authors.lastname: Heuertz
authors.forename: M C
authors.initials: MC
authors.lastname: Fulchignoni-Lataud
authors.forename: N
authors.initials: N
authors.lastname: Dahl
authors.forename: P
authors.initials: P
authors.lastname: Labrune
authors.forename: B
authors.initials: B
authors.lastname: Le Marec
authors.forename: C
authors.initials: C
authors.lastname: Piussan
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D005124:Eye Abnormalities / Q000235:genetics; D005260:Female; D005796:Genes; D005819:Genetic Markers; D006801:Humans; D007184:Incontinentia Pigmenti / Q000235:genetics*; D008126:Lod Score; D008297:Male; D051379:Mice; D010375:Pedigree; D013045:Species Specificity; D014960:X Chromosome
chemical_list: D005819:Genetic Markers