title: Open tibial fracture infections in asymptomatic HIV antibody-positive patients.
abstract: Fourteen patients with 15 open tibial fractures were examined retrospectively to compare postoperative infection rates of asymptomatic patients who tested positive or negative for the human immunodeficiency virus antibody (HIVab). All patients were treated with a standard open-fracture protocol. All of the HIVab-positive patients developed postoperative infections. There were five postoperative infections in 4 patients; 3 of the 4 patients were HIVab-positive and 2 of these patients developed chronic osteomyelitis. The only other infection, in an HIVab-negative patient with insulin-dependent diabetes, resolved without complication. All other HIVab-negative patients had no complications. The infection rate for asymptomatic HIVab-positive patients with open tibial fractures was higher than that for HIVab-negative patients in our study. These data suggest that the HIV status of patients with open tibial fractures is relevant to treatment outcome.
authors.affiliation: Department of Orthopaedic Surgery, Catholic Medical Center of Brooklyn & Queens, New York.
authors.forename: E D
authors.initials: ED
authors.lastname: O'Brien
authors.forename: J R
authors.initials: JR
authors.lastname: Denton
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D005597:Fractures, Open / Q000150:complications / Q000276:immunology / Q000601:surgery*; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000382:microbiology; D012189:Retrospective Studies; D013978:Tibial Fractures / Q000150:complications / Q000276:immunology / Q000601:surgery*