title: A haemolytic cell-free preparation of Moraxella bovis confers protection against infectious bovine keratoconjunctivitis.
abstract: Protection conferred by a cell-free preparation from a haemolytic Moraxella bovis isolate, UQV 148NF, was compared to an equivalent fraction from a non-haemolytic M. bovis isolate, Gordon 26L3, and to a recombinant DNA-derived pili vaccine. Three groups of ten calves were vaccinated twice with one of the three preparations and, together with ten non-vaccinated calves, challenged with virulent M. bovis isolate Dal 2d. Compared to the control group, significant protection was observed in the group receiving the pili vaccine and the group receiving the preparation from haemolytic isolate, UQV 148NF.
authors.affiliation: University of Sydney, Department of Animal Health, Camden, NSW, Australia.
authors.forename: F M
authors.initials: FM
authors.lastname: Billson
authors.forename: J L
authors.initials: JL
authors.lastname: Hodgson
authors.forename: J R
authors.initials: JR
authors.lastname: Egerton
authors.forename: A W
authors.initials: AW
authors.lastname: Lepper
authors.forename: W P
authors.initials: WP
authors.lastname: Michalski
authors.forename: C L
authors.initials: CL
authors.lastname: Schwartzkoff
authors.forename: P R
authors.initials: PR
authors.lastname: Lehrbach
authors.forename: J M
authors.initials: JM
authors.lastname: Tennent
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D000942:Antigens, Bacterial / Q000276:immunology / Q000302:isolation & purification; D001428:Bacterial Vaccines / Q000276:immunology; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D010861:Fimbriae, Bacterial / Q000276:immunology; D006460:Hemolysin Proteins / Q000276:immunology* / Q000302:isolation & purification; D007639:Keratoconjunctivitis, Infectious / Q000517:prevention & control*; D016955:Moraxella bovis / Q000276:immunology* / Q000472:pathogenicity; D016870:Neisseriaceae Infections / Q000517:prevention & control / Q000662:veterinary*; D014614:Vaccines, Synthetic / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D006460:Hemolysin Proteins; D014614:Vaccines, Synthetic