Endoscopic and histologic resolution of gastric pseudolymphoma (reactive lymphoid hyperplasia) following treatment with bismuth and oral antibiotics.
Gastric pseudolymphoma is a rare disorder of unknown etiology that can undergo transformation into malignant lymphoma. This report describes the first case of a gastric pseudolymphoma associated with Helicobacter pylori infection that underwent complete clinical, endoscopic, and histologic resolution following treatment with bismuth subsalicylate, amoxicillin, and metronidazole. The eradication of Helicobacter pylori may have eliminated ongoing antigenic stimulation that has previously been postulated to be responsible for the development and subsequent progression of gastric pseudolymphoma.
Weston
A P
AP
Division of Gastroenterology, University of Kansas School of Medicine, Kansas City.
Campbell
D R
DR
McGregor
D H
DH
Cherian
R
R
D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use*; D001706:Biopsy; D001729:Bismuth / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005753:Gastric Mucosa / Q000473:pathology*; D016481:Helicobacter Infections / Q000188:drug therapy; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D006965:Hyperplasia; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000382:microbiology* / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D009942:Organometallic Compounds / Q000627:therapeutic use*; D011899:Ranitidine / Q000627:therapeutic use; D012459:Salicylates / Q000627:therapeutic use*; D013270:Stomach / Q000473:pathology*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000382:microbiology* / Q000473:pathology
D009942:Organometallic Compounds; D012459:Salicylates; D008795:Metronidazole; C015715:bismuth subsalicylate; D000658:Amoxicillin; D011899:Ranitidine; D001729:Bismuth