title: [A case of peritoneal metastasis of breast cancer successfully treated by multidisciplinary therapy with hyperthermia therapy].
abstract: A 53-year-old female with peritoneal metastasis of breast cancer was treated with hyperthermia with chemotherapy. One course consisted of THP 60 mg and FT 400 mg/iv (day 1), CPM 100 mg and MPA 800 mg/daily/po) with RF heating of hyperthermia monthly. After completion of 10 courses of this regimen, ascites completely disappeared and peritoneal metastases were not found observed in any peritoneal cavity with abdominal CT and ultrasound. Peritoneal metastasis of breast cancer was one of the worst reactions with any therapy. The patient has been living for about four years without any signs of recurrence, with the tumor markers within the normal range after surgery. Thermochemotherapy seems a very promising treatment modality for peritoneal metastasis of breast cancer.
authors.affiliation: Dept. of Surgery, Tokyo Medical College.
authors.forename: M
authors.initials: M
authors.lastname: Kusama
authors.forename: K
authors.initials: K
authors.lastname: Kimura
authors.forename: Y
authors.initials: Y
authors.lastname: Koyanagi
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Ebihara
authors.forename: M
authors.initials: M
authors.lastname: Arima
authors.forename: A
authors.initials: A
authors.lastname: Murata
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Matsunaga
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000473:pathology*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008207:Lymphatic Metastasis; D008875:Middle Aged; D010404:Penicillin V / Q000008:administration & dosage / Q000031:analogs & derivatives; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000628:therapy*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D005641:Tegafur; D004317:Doxorubicin; D003520:Cyclophosphamide; C027260:pirarubicin; C100209:phenethicillin; D010404:Penicillin V