title: Highly invasive papillary thyroid carcinoma.
abstract: Papillary carcinoma is the most common malignant tumour of the thyroid gland, accounting for at least two-thirds of newly diagnosed carcinomas. This tumour may be occasionally multicentric in origin. It frequently spreads to regional lymph nodes in the neck and mediastinum, but uncommonly metastasizes outside these regions. Local invasion of this tumour to the upper airway or digestive tract structures is infrequent. However, when that occurs, it is a source of significant morbidity and mortality. In the last two years four patients suffering from invasive papillary carcinoma to the aerodigestive tract were treated in our department. A short case history of one of them is presented and current trends in management of the disease are reviewed.
authors.affiliation: Department of Otorhinolaryngology, Rambam Medical Centre, Haifa, Israel.
authors.forename: T
authors.initials: T
authors.lastname: Hefer
authors.forename: H Z
authors.initials: HZ
authors.lastname: Joachims
authors.forename: A
authors.initials: A
authors.lastname: Eitan
authors.forename: A
authors.initials: A
authors.lastname: Golz
authors.forename: J
authors.initials: J
authors.lastname: Brown
mesh_terms: D002291:Carcinoma, Papillary / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013964:Thyroid Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014134:Tracheal Neoplasms / Q000473:pathology*