title: Indoor air pollution and asthma. Results from a panel study.
abstract: Although there is abundant clinical evidence of asthmatic responses to indoor aeroallergens, the symptomatic impacts of other common indoor air pollutants from gas stoves, fireplaces, and environmental tobacco smoke have been less well characterized. These combustion sources produce a complex mixture of pollutants, many of which are respiratory irritants. We report here results of an analysis of associations between indoor pollution and several outcomes of respiratory morbidity in a population of adult asthmatics residing in the Denver, Colorado, metropolitan area. A panel of 164 asthmatics recorded in a daily diary the occurrence of several respiratory symptoms, nocturnal asthma, medication use, and restrictions in activity, as well as the use of gas stoves, wood stoves, or fireplaces, and exposure to environmental tobacco smoke. Multiple logistic regression analysis suggests that the indoor sources of combustion have a statistically significant association with exacerbations of asthma. For example, after correcting for repeated measures and autocorrelation, the reported use of a gas stove was associated with moderate or worse shortness of breath (OR, 1.60; 95% CI, 1.11-2.32), moderate or worse cough (OR, 1.71; 95% CI, 0.97-3.01), nocturnal asthma (OR, 1.01; 95% CI, 0.91-1.13), and restrictions in activity (OR, 1.47; 95% CI, 1.0-2.16). Among this panel of relatively moderate to severe asthmatics, the respiratory irritants produced by several domestic combustion sources were associated with increased morbidity.
authors.affiliation: California Environmental Protection Agency, Berkeley 94704.
authors.forename: B D
authors.initials: BD
authors.lastname: Ostro
authors.forename: M J
authors.initials: MJ
authors.lastname: Lipsett
authors.forename: J K
authors.initials: JK
authors.lastname: Mann
authors.forename: M B
authors.initials: MB
authors.lastname: Wiener
authors.forename: J
authors.initials: J
authors.lastname: Selner
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D000368:Aged; D016902:Air Pollution, Indoor / Q000009:adverse effects*; D001249:Asthma / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D003120:Colorado / Q000453:epidemiology; D003296:Cooking; D005260:Female; D005579:Fossil Fuels; D006296:Health Services / Q000706:statistics & numerical data; D006361:Heating / Q000009:adverse effects; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012307:Risk Factors; D012621:Seasons; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014028:Tobacco Smoke Pollution / Q000009:adverse effects; D014505:Urban Population; D014934:Wood
chemical_list: D005579:Fossil Fuels; D014028:Tobacco Smoke Pollution