title: Specular microscopy of corneal endothelial cells in cynomolgus monkeys.
abstract: The corneal endothelia of 15 male and 16 female cynomolgus monkeys (estimated age: 2 years and more) were examined with a contact-type specular microscope under general anesthesia. The specular microscopy showed uniform-sized, hexagonal endothelia arranged regularly on the innermost layer of the cornea. Concerning the cell density (cells/mm2), no statistically significant difference was observed between the left and right eyes or between sexes. However, the cell density decreased in monkeys over 7 years old.
authors.affiliation: Preclinical Research Division, Central Institute for Experimental Animals, Kawasaki, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Morita
authors.forename: K
authors.initials: K
authors.lastname: Shimomura
authors.forename: Y
authors.initials: Y
authors.lastname: Sakuma
mesh_terms: D000375:Aging / Q000473:pathology; D000818:Animals; D002452:Cell Count; D004728:Endothelium, Corneal / Q000033:anatomy & histology*; D005260:Female; D008252:Macaca fascicularis / Q000033:anatomy & histology*; D008297:Male; D008853:Microscopy / Q000379:methods*; D012727:Sex Characteristics