Cytologic study of renal angiomyolipoma by fine-needle aspiration biopsy: report of four cases.
Four cases of renal angiomyolipoma (AML) diagnosed by fine-needle aspiration biopsy (FNAB) are reported. One case was associated with the clinical complex of tuberous sclerosis. The tumors were solitary in two cases and multiple and bilateral in the fourth. The cytologic features of the four cases were similar to those described in the literature: smooth muscle cells intermingled with mature fat cells and blood vessels, together with a lipoidic background. These tumors are currently considered benign although they may present characteristics accepted as criteria of malignancy in other tumors: pleomorphism and atypical smooth muscle cells, vascular invasion, capsular rupture, and lymphatic involvement. We conclude that it is important and possible to establish preoperative cytologic diagnosis, since treatment of these tumors is conservative and obviates aggressive nephrectomy.
Tallada
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N
Department of Pathology, Ciutat Sanitària Universitària Vall d'Hebrón, Universitat Autònoma de Barcelona, Spain.
Martinez
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S
Raventos
A
A
D000293:Adolescent; D000328:Adult; D018207:Angiomyolipoma / Q000473:pathology*; D001707:Biopsy, Needle / Q000379:methods; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008875:Middle Aged