title: [Receptors for the Fc fragment of IgG (RFc gamma): membrane forms and soluble forms].
abstract: Membrane and soluble forms of Fc gamma receptors play important role in immune reactions. Upon interaction with immune complexes, Fc gamma R transduce activation or inhibition signals via their intracytoplasmic portions. Soluble Fc gamma R contain the Fc gamma R ectodomain. They bind to the Fc portion of IgG and inhibit Fc dependent immune reactions. In addition, they bind directly to various cell types and regulate immune reactions.
authors.affiliation: INSERM Unité 255, Immunologie Cellulaire et Clinique, Institut Curie, Paris.
authors.forename: C
authors.initials: C
authors.lastname: Sautès
authors.forename: W H
authors.initials: WH
authors.lastname: Fridman
mesh_terms: D000818:Animals; D006801:Humans; D015471:Leukemia, Basophilic, Acute / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000473:pathology; D051379:Mice; D051381:Rats; D017452:Receptors, IgG / Q000276:immunology / Q000378:metabolism* / Q000648:ultrastructure*; D015398:Signal Transduction; D012995:Solubility; D014407:Tumor Cells, Cultured / Q000378:metabolism
chemical_list: D017452:Receptors, IgG
vernacular_title: Les récepteurs pour le fragment Fc des IgG (RFc gamma): formes membranaires et formes solubles.