title: [The two cases of examination of chemotherapy in advanced gallbladder carcinoma].
abstract: Two cases of advanced carcinoma of gallbladder were treated by combination chemotherapy consisting of 5-FU, leucovorin and continuous administration of etoposide. One of the cases was a male 61 years old and another was a female 64 years old, both of whom were diagnosed as inoperable cases by imaging studies. When combination chemotherapy consisting of 5-FU (750mg/day or 1,000mg/day infusion) was given, leucovorin (30mg/day) and etoposide (25mg/day oral or 33mg/day continuous infusion), angiography or other imaging studies pointed out a reduction in their lesions of over 50%, and their QOL was markedly improved.
authors.affiliation: Dept. of Surgery, Megumino Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Shibata
authors.forename: O
authors.initials: O
authors.lastname: Mishima
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Kondo
authors.forename: E
authors.initials: E
authors.lastname: Sasaki
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: J
authors.initials: J
authors.lastname: Uchino
authors.forename: K
authors.initials: K
authors.lastname: Futakuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Nomura
mesh_terms: D000284:Administration, Oral; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005706:Gallbladder Neoplasms / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged
chemical_list: D005047:Etoposide; D002955:Leucovorin; D005472:Fluorouracil