Angiotensinogen Met235-->Thr polymorphism in a London normotensive and hypertensive black and white population.
We describe angiotensinogen gene (AGT) polymorphic frequencies in different ethnic groups in London, both normotensive and hypertensive. The methodology is a recently described direct PCR technique. Results show that there is a marked difference in T-235 frequency between ethnic groups. However, there was no apparent association of T-235 with hypertension.
Barley
J
J
Medical Genetics Unit, St. George's Hospital Medical School, London, UK.
Blackwood
A
A
Sagnella
G
G
Markandu
N
N
MacGregor
G
G
Carter
N
N
D000808:Angiotensinogen / Q000097:blood / Q000235:genetics*; D044383:Black People / Q000235:genetics*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000208:ethnology / Q000235:genetics*; D008131:London; D016133:Polymerase Chain Reaction; D044465:White People / Q000235:genetics*
D000808:Angiotensinogen