title: Fasciitis (not scleroderma) following prolonged exposure to an organic solvent (trichloroethylene).
abstract: We describe 2 cases of diffuse fasciitis with eosinophilia (DFE) associated with prolonged exposure to the industrial solvent trichloroethylene (TCE). The medical and personal histories, examinations, and laboratory and pathological investigations were reviewed and summarized. The 2 case reports, representing the first and 2nd cases of DFE associated with TCE, were compared with 8 reported cases of systemic sclerosis associated with TCE and suggest a direct association between TCE exposure and the development of fasciitis (DFE).
authors.affiliation: Department of Medicine, Medical University of South Carolina, Charleston 29425-2229.
authors.forename: P A
authors.initials: PA
authors.lastname: Waller
authors.forename: D
authors.initials: D
authors.lastname: Clauw
authors.forename: T
authors.initials: T
authors.lastname: Cupps
authors.forename: J S
authors.initials: JS
authors.lastname: Metcalf
authors.forename: R M
authors.initials: RM
authors.lastname: Silver
authors.forename: E C
authors.initials: EC
authors.lastname: Leroy
mesh_terms: D000368:Aged; D004781:Environmental Exposure; D004802:Eosinophilia / Q000139:chemically induced* / Q000473:pathology; D005208:Fasciitis / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D055585:Physical Phenomena; D010825:Physics; D012595:Scleroderma, Systemic / Q000139:chemically induced / Q000473:pathology; D014241:Trichloroethylene / Q000009:adverse effects*
chemical_list: D014241:Trichloroethylene