[Cerebral venous thrombosis disclosing Behçet disease].
BACKGROUND
Behçet's disease is very occasionally revealed by thrombophlebitis in children. Dural sinus thrombosis can be one of its complication.


METHODS
A 14 year-old boy of Mediterranean origin was admitted for acute meningitis with temperature of 40 degrees C. His CSF contained 24 cells/ml and 0.33 g/l protein; it was sterile. The RBC sedimentation rate was 84 mm. Other investigations, including brain scan, were negative. The condition became worse, with a deterioration of visual acuity, attack of aphthous stomatitis and skin lesions at points of puncture. There was papilledema with retinal vascularitis. A second brain scan and MRI showed sagittal sinus thrombosis. The condition improved immediately after treatment with prednisolone and ticlopidine. The brain MRI taken 3 months later showed partial permeability of the sagittal sinus. The patient had several attacks of meningoencephalitis and stomatitis during the following 2 years. The last attack was complicated by iridocyclitis; this required cyclosporin treatment.


CONCLUSIONS
Phlebothrombosis is a classic complication of Behçet's disease and can reveal the disease. Sagittal sinus thrombosis has never before been reported as the first manifestation of the disease in children.
Humberclaude
V
V
Service des Maladies Infectieuses et Neurologie Infantiles, Hôpital B, CHRU, Lille.
Vallée
L
L
Sukno
S
S
Vamecq
J
J
Dhellemmes
S
S
Pruvo
J P
JP
Nuyts
J P
JP
D000293:Adolescent; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002550:Cerebral Veins; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000517:prevention & control; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012008:Recurrence; D013997:Time Factors
D010975:Platelet Aggregation Inhibitors
Thrombose veineuse cérébrale révélant une maladie de Behçet.