Effects of oleic and elaidic acids on in vitro intestinal uptake of cholesterol in the rat.
The effects of oleic and elaidic acid upon the in vitro intestinal uptake of cholesterol were studied in 9 weeks-old male and female rats. Elaidic acid increases the uptake of cholesterol when compared to oleic acid in both males and females. It is suggested that elaidic acid may enhance the esterification of cholesterol within the enterocyte through being more available for esterification and/or through being preferentially incorporated into cholesterol esters.
Manteca
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X
Unit of Physiology, Veterinary Faculty, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Fernández
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E
Goñalons
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E
D000818:Animals; D002784:Cholesterol / Q000378:metabolism*; D004951:Esterification; D005260:Female; D007408:Intestinal Absorption / Q000187:drug effects*; D008297:Male; D019301:Oleic Acid; D009829:Oleic Acids / Q000494:pharmacology*; D051381:Rats
D009829:Oleic Acids; D019301:Oleic Acid; C011459:elaidic acid; D002784:Cholesterol