Malignant rhabdoid tumour of the pineal region.
A 9-month-old male presented to hospital with signs and symptoms of raised intracranial pressure. A CT scan showed obstructive hydrocephalus from a large pineal region mass lesion into which an intratumoral hemorrhage had occurred. A posterior fossa craniectomy and subtotal excision of the mass lesion were performed. By histopathology, the lesion was a malignant rhabdoid tumour (MRT). Despite surgery and chemotherapy, the tumour grew inexorably, and the patient died four months after the initial diagnosis. MRT is a rare and highly invasive neoplasm which infrequently arises from the central nervous system. This is the first documented case of a MRT arising from the pineal region. The clinical, radiographic, and pathological features of the MRT in this patient are presented.
Muller
M
M
Brain Tumour Research Laboratory, Hospital for Sick Children, University of Toronto, Ontario.
Hubbard
S L
SL
Provias
J
J
Greenberg
M
M
Becker
L E
LE
Rutka
J T
JT
D001932:Brain Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008854:Microscopy, Electron; D010870:Pineal Gland / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D011859:Radiography; D018335:Rhabdoid Tumor / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure