Chromosome rearrangements and human gene mapping.
The successful mapping of numerous mendelian disorders by chromosome rearrangements turned out to be a key method for positional location of disease genes. We present some personal observations and comments on the interest of cytogenetic studies in human gene mapping.
Gilgenkrantz
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S
Laboratoire de Génétique Humaine, Centre Régional de transfusion Sanguine, Vandoeuvre-les-Nancy, France.
Philippe
C
C
Chery
M
M
D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D015321:Gene Rearrangement / Q000235:genetics*; D008040:Genetic Linkage; D006801:Humans; D007223:Infant; D014960:X Chromosome / Q000235:genetics