title: Pulmozyme--Dornase alfa.
abstract: Dornase alfa is the first new drug released in 30 years for the treatment of patients with CF. Although it does not represent a replacement for current standard therapies, it is an effective agent in improving lung function. The development of this drug has helped to provide treatment to a medical problem that physicians have struggled with treating for years.
authors.forename: C
authors.initials: C
authors.lastname: Gutteridge
authors.forename: R J
authors.initials: RJ
authors.lastname: Kuhn
mesh_terms: D002648:Child; D003550:Cystic Fibrosis / Q000188:drug therapy*; D003850:Deoxyribonuclease I / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; C085693:DNASE1 protein, human; D003850:Deoxyribonuclease I