title: [Peroxide radicals in the metabolism of toxic substances].
abstract: The free radicals resulting from the metabolism of oxygen and some xenobiotics, can induce, when a limit concentration is exceeded, toxic effects due to their action on DNA, enzymes and fatty acids. Therefore, the association of oxygen therapy with drug administration may have a more or less beneficial effect. Thus, in a long-term treatment with drugs which by metabolized release free radicals, the use of exogenous compounds for protecting the human body need to be administered.
authors.affiliation: Disciplina de Toxicologie, Universitatea de Medicină şi Farmacie Iaşi.
authors.forename: M
authors.initials: M
authors.lastname: Proca
authors.forename: L
authors.initials: L
authors.lastname: Agoroaei
authors.forename: E
authors.initials: E
authors.lastname: Butnaru
authors.forename: M
authors.initials: M
authors.lastname: Cotrău
mesh_terms: D005609:Free Radicals; D006801:Humans; D010084:Oxidation-Reduction; D010545:Peroxides / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism; D015262:Xenobiotics / Q000493:pharmacokinetics*
chemical_list: D005609:Free Radicals; D010545:Peroxides; D017382:Reactive Oxygen Species; D015262:Xenobiotics
vernacular_title: Radicalii peroxidici în metabolizarea substanţelor toxice.