title: Peroxide accumulation in detergents.
abstract: It is known that polyether detergents have a propensity for peroxide accumulation but the rate of this accumulation and the conditions under which it occurs are not well-appreciated. We here describe the use of the FOX (ferrous oxidation in Xylenol orange) assay as a screen for detergent peroxide accumulation. We also show that a chain-breaking antioxidant, but not a metal-chelating agent block peroxide accumulation in detergent stored in the light at room temperature.
authors.affiliation: Department of Medicine, University College London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Jaeger
authors.forename: K
authors.initials: K
authors.lastname: Sorensen
authors.forename: S P
authors.initials: SP
authors.lastname: Wolff
mesh_terms: D002084:Butylated Hydroxytoluene; D003624:Darkness; D003902:Detergents; D004340:Drug Contamination; D004355:Drug Stability; D005456:Fluorescent Dyes; D007700:Kinetics; D008027:Light; D017830:Octoxynol; D010084:Oxidation-Reduction; D010545:Peroxides / Q000032:analysis*; D010636:Phenols; D011136:Polysorbates; D013454:Sulfoxides; D013997:Time Factors; D014992:Xylenes
chemical_list: D003902:Detergents; D005456:Fluorescent Dyes; D010545:Peroxides; D010636:Phenols; D011136:Polysorbates; D013454:Sulfoxides; D014992:Xylenes; D002084:Butylated Hydroxytoluene; D017830:Octoxynol; C016833:xylenol orange