Cisapride for the treatment of nausea produced by selective serotonin reuptake inhibitors.
A low dose of cisapride (5 mg b.i.d.) produced rapid relief from nausea elicited by the initiation of treatment with a selective serotonin reuptake inhibitor in eight patients. This effect of cisapride is presumably related to its serotonin3 antagonistic property.
Bergeron
R
R
Department of Psychiatry, McGill University, Montreal, Que., Canada.
Blier
P
P
D000328:Adult; D020117:Cisapride; D003866:Depressive Disorder / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D009325:Nausea / Q000139:chemically induced* / Q000188:drug therapy* / Q000517:prevention & control; D010880:Piperidines / Q000008:administration & dosage / Q000627:therapeutic use*; D012702:Serotonin Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use
D020117:Cisapride; D010880:Piperidines; D012702:Serotonin Antagonists; D017367:Selective Serotonin Reuptake Inhibitors