Piroxicam induced pulmonary infiltrates and eosinophilia.
We describe 2 patients who developed pulmonary infiltrates while being treated with piroxicam. There was no satisfactory explanation other than drug induced lung disease for their illness. They had no exposure to pneumotoxic drugs or aerocontaminants. Microorganisms were not cultured in sputum or bronchoaveolar lavage. There was no underlying illness with possible lung involvement. Pulmonary infiltrates developed during piroxicam therapy, disappeared after drug withdrawal and recurred following rechallenge.
Pfitzenmeyer
P
P
Service de Gériatrie, Centre Hospitalier Régional et Universitaire de Dijon, France.
Meier
M
M
Zuck
P
P
Peiffer
G
G
Masson
P
P
Turcu
A
A
Piard
F
F
Camus
P
P
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D010894:Piroxicam / Q000009:adverse effects*; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography
D010894:Piroxicam