title: Effect of pegs and screws on bone ingrowth in cementless total knee arthroplasty.
abstract: The purpose of the present study was to assess the effects of pegs and screws on bone ingrowth into the tibial component in cementless total knee replacement. Left total knee replacements were performed in 21 mature male dogs with 3 cementless porous-coated tibial tray configurations (7 animals per group): (1) 4-peg design implanted with cortical screws passing through the pegs; (2) 4-peg design implanted without screws; and (3) pegless design secured by 4 cortical screws. The animals were allowed unrestricted activity and were euthanized 6 months postoperatively. The pegless components (Group 3) had the highest extent of bone ingrowth into the tray (90.3% +/- 9.4%), followed by the components with 4 pegs only (Group 2, 82.8% +/- 9.2%), and the components with 4 pegs and 4 screws (Group 1, 75.9% +/- 11.8%). The difference between Groups 1 and 3 was statistically significant (p < 0.05). The volume fraction of bone ingrowth in the tray did not differ among the 3 groups, with an overall mean of 22.5% (+/- 4.6%). At the posterolateral quadrant, Group 1 had significantly less bone ingrowth than Group 3 within the tray whether measured as the extent (63.6% +/- 20.5% versus 91.0% +/- 10.6%, p < 0.05) or volume fraction (19.1% +/- 8.8% versus 32.9% +/- 10.5%, p < 0.05). There were no between-group differences at the other quadrants. This study indicated that pegs provided no added benefit in a circumstance where sufficient initial fixation was obtained with screws.
authors.affiliation: Department of Orthopedic Surgery, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612.
authors.forename: D R
authors.initials: DR
authors.lastname: Sumner
authors.forename: T M
authors.initials: TM
authors.lastname: Turner
authors.forename: D
authors.initials: D
authors.lastname: Dawson
authors.forename: A G
authors.initials: AG
authors.lastname: Rosenberg
authors.forename: R M
authors.initials: RM
authors.lastname: Urban
authors.forename: J O
authors.initials: JO
authors.lastname: Galante
mesh_terms: D000818:Animals; D001843:Bone Cements; D001863:Bone Screws; D004285:Dogs; D007720:Knee Prosthesis / Q000295:instrumentation; D008297:Male
chemical_list: D001843:Bone Cements