title: Alterations in renal function in experimental congestive heart failure.
abstract: The delicate interplay between vasoconstrictors and vasodilators preserves glomerular filtration in CHF despite marked hypoperfusion. Activation of vasoconstrictive systems seems to depend on the severity and the chronicity of the disease. The importance of renin-angiotensin, sympathetic nerves, vasopressin and counterregulatory ANP, and prostaglandins in CHF has been elucidated. Possible roles of newly identified substances, such as endothelin and EDRF, deserve investigation.
authors.affiliation: Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Awazu
authors.forename: I
authors.initials: I
authors.lastname: Ichikawa
mesh_terms: D000818:Animals; D009320:Atrial Natriuretic Factor / Q000502:physiology; D004285:Dogs; D004298:Dopamine / Q000502:physiology; D016232:Endothelins / Q000502:physiology; D006333:Heart Failure / Q000503:physiopathology*; D007668:Kidney / Q000503:physiopathology*; D020097:Natriuretic Peptide, Brain; D009419:Nerve Tissue Proteins / Q000502:physiology; D009569:Nitric Oxide / Q000502:physiology; D011453:Prostaglandins / Q000502:physiology; D051381:Rats; D012084:Renin-Angiotensin System / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology; D014667:Vasopressins / Q000502:physiology; D014883:Water-Electrolyte Imbalance / Q000503:physiopathology
chemical_list: D016232:Endothelins; D009419:Nerve Tissue Proteins; D011453:Prostaglandins; D014667:Vasopressins; D020097:Natriuretic Peptide, Brain; D009569:Nitric Oxide; D009320:Atrial Natriuretic Factor; D004298:Dopamine