title: [Adverse reactions to drugs in a health center].
abstract: OBJECTIVE
  To study the adverse side-effects to medication and define their principle characteristics.
  
  
  METHODS
  A descriptive, crossover, observation study with no random distribution.
  
  
  METHODS
  The population cared for at a Health Centre in Toledo.
  
  
  METHODS
  Those over 15 years old during a 6-month period.
  
  
  RESULTS
  64 adverse side-effects were detected, classified as follows: definite, 10.9%; probable, 68.7%; possible, 20.3%. The rate of adverse side-effects was 2.67 per thousand prescriptions and 2.22 per thousand consultations. Distribution by gender was 62.5% women and 37.5% men. The 35-45 age group was the one with most adverse side-effects. The most affected systems were the digestive apparatus (46.50%), followed by the nervous system (27.50%) and the skin (16.22%). The most commonly involved pharmacological groups were: analgesics and non-steroid anti-inflammatories (34.37%) and drugs for the cardiovascular system (26.56%). 98.43% were trivial and none serious. Evolution was: 59.37% recovered on stopping the drug and 23.43% with the help of treatment.
  
  
  CONCLUSIONS
  The number of suspected adverse side-effects in the Centre is high, but they were trivial. It was confirmed that adverse side-effects suppose a frequent medical problem in Primary Care. It is important to make health professionals aware so that, when prescribing, they bear in mind the drug risk/benefit relationship. The identification and communication of adverse side-effects, especially of medicines newly on the market, is also important.
authors.affiliation: Centro de Salud, Toledo.
authors.forename: M J
authors.initials: MJ
authors.lastname: de Frutos Hernansanz
authors.forename: A
authors.initials: A
authors.lastname: Lázaro Damas
authors.forename: V
authors.initials: V
authors.lastname: Llinares Gómez
authors.forename: M
authors.initials: M
authors.lastname: Azpiazu Garrido
authors.forename: A
authors.initials: A
authors.lastname: Serrano Vázquez
authors.forename: F
authors.initials: F
authors.lastname: López de Castro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003151:Community Health Centers; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013030:Spain; D013223:Statistics as Topic
vernacular_title: Reacciones adversas a medicamentos en un centro de salud.