A survey of methods of processing and storage of bone marrow and blood stem cells in the EBMT.
We conducted a survey to identify current practices in bone marrow processing, preservation and storage by mailing a questionnaire to 155 bone marrow transplant centres listed in the EBMT records. Approximately 57% of centres replied. There were wide variations in methodology which reflected the different types of disease being treated, local conditions and personal preferences. A number of areas where more caution could be exercised were identified: possible reinfusion of excessive quantities of heparin, possible misuse of disposable needles and lack of awareness of the implications of product liability rules relating to cooling rate, storage and viability data.
Elliott
C
C
Charing Cross Hospital, London, UK.
McCarthy
D
D
D000925:Anticoagulants; D001853:Bone Marrow; D016026:Bone Marrow Transplantation; D002470:Cell Survival; D015925:Cryopreservation; D003625:Data Collection; D005060:Europe; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells; D006801:Humans; D007938:Leukemia / Q000628:therapy; D009369:Neoplasms / Q000628:therapy; D011786:Quality Control; D012042:Registries; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D014015:Tissue Banks / Q000592:standards
D000925:Anticoagulants