Effect of a peptide fraction extracted from mitochondrial DNA on rat liver cell viability.
The authors verified the effect of a peptidic fraction from mitochondrial DNA on liver cell cultures. Primary cultures treated with the mitochondrial peptidic fraction (final concentration 0.025 O.D./ml) showed a higher viability after 48 hours with respect to cultures without mitochondrial peptidic fraction (p < 0.05). The results indicate a probable action of the mitochondrial peptidic fraction on liver cell viability.
Chimenti
R
R
Department of Cell Biology, University of Calabria, Rende, CS.
Marotta
M
M
Spena
A
A
Covello
M
M
Pitrelli
G
G
Covello
C
C
D000818:Animals; D002417:Cattle; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D004272:DNA, Mitochondrial / Q000032:analysis*; D008099:Liver / Q000166:cytology / Q000187:drug effects*; D008930:Mitochondria, Liver / Q000737:chemistry*; D010455:Peptides / Q000494:pharmacology*; D051381:Rats
D004272:DNA, Mitochondrial; D010455:Peptides