title: The interaction of the vanadyl (IV) cation with chondroitin sulfate A.
abstract: The interaction of VO2+ with the muchopolysaccharide chondroitin sulfate A (CSA) has been investigated by electron absorption spectroscopy and infrared measurements in aqueous solutions at different pH-values and ligand to metal ratios up to 6:1. The generation of a VO(CSA)2 species could be demonstrated. Coordination of the oxocation through the carboxylate group and the glycosidic oxygen of the D-glucuronate moieties is suggested. Infrared spectra of some poorly characterized solid VO/CSA complexes point to the same bonding characteristics. Preliminary results obtained at higher ligand to metal ratios suggest a different coordination behavior.
authors.affiliation: Química Inorgánica (QUINOR), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina.
authors.forename: S B
authors.initials: SB
authors.lastname: Etcheverry
authors.forename: P A
authors.initials: PA
authors.lastname: Williams
authors.forename: E J
authors.initials: EJ
authors.lastname: Baran
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002809:Chondroitin Sulfates / Q000737:chemistry*; D008969:Molecular Sequence Data; D015394:Molecular Structure; D012996:Solutions; D013053:Spectrophotometry; D013055:Spectrophotometry, Infrared; D014638:Vanadates / Q000737:chemistry*
chemical_list: D012996:Solutions; D014638:Vanadates; D002809:Chondroitin Sulfates