title: [Stress shielding and fracture healing].
abstract: The influence of stress shielding after fracture fixation with plate on fracture healing was studied. The results of animal and biomechanical experiments as well as the clinical observations demonstrated that rigidity of the plate was not the only factor causing stress redistribution and stress shielding effects of bone. Either the internal fixation with different implants or external fixation with fixators all might lead to physical and chemical characteristic changes of bone tissue. In the early stage, the disturbance of blood supply and the bone structure remodeling may be the main reasons. Reaction to the implant was another cause in the middle stage. If the affected limb can take weight-bearing normally at late stage, the influences of plate on fracture healing mechanical properties of bone and the osteoporosis cause by stress shielding effects will become much less. The tissue of the affected limb was the most important factor which may cause osteoporosis and refracture. Osteoporosis, bone atrophy and immobilization syndrome of bone and joint can be prevented and treated by taking normal weight-bearing and overcoming infection and implant reaction.
authors.affiliation: Department of Orthopaedics, First Teaching Hospital, Norman Bethune University of Medical Sciences, Changchun.
authors.forename: J G
authors.initials: JG
authors.lastname: Liu
authors.forename: X X
authors.initials: XX
authors.lastname: Xu
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001860:Bone Plates / Q000009:adverse effects*; D004285:Dogs; D005264:Femoral Fractures / Q000601:surgery; D005592:Fracture Fixation / Q000009:adverse effects*; D017102:Fracture Healing; D006801:Humans; D010024:Osteoporosis / Q000209:etiology; D013314:Stress, Mechanical; D013978:Tibial Fractures / Q000601:surgery