Ultrastructure of lamellar granules coating glial cell basal lamina in the olfactory bulb and olfactory subtracts of goldfish.
Lamellar granules, 35 to 80 nm in diameter, are observed in the pia-arachnoid tissue of regenerated olfactory bulb and olfactory subtracts of the goldfish. The granules correspond to multiple stacks of disks which cover basal lamina of both pial and ependymal cell layers and blood vessels. The granules are also in close association with collagen fibril bundles. The granules are observed only in young goldfish or after bilateral olfactory tract transection in 1 year postoperated animals. Our findings suggest that these granules are secreted by connective tissue cells in response to damage associated with bilateral olfactory tract transection. Coexisting extracellular free granules and the granules covering basal lamina are simultaneously found in regenerated olfactory bulb and olfactory tract. Many of our findings, as far as we know, have not been described previously. The composition and function of these granules are at present unknown.
Popov
V I
VI
Institute for Cell Biophysics, Russian Academy of Sciences, Pushchino.
Moisseeva
A A
AA
Zippel
H P
HP
D000375:Aging; D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D004805:Ependyma / Q000254:growth & development / Q000648:ultrastructure; D006054:Goldfish; D008854:Microscopy, Electron; D009457:Neuroglia / Q000502:physiology / Q000648:ultrastructure*; D009830:Olfactory Bulb / Q000254:growth & development / Q000648:ultrastructure*; D009833:Olfactory Pathways / Q000254:growth & development / Q000648:ultrastructure*