[Familial thymoma and translocation t (14;20) (q24;p13)].
A familial lympho-epithelial thymoma with constitutional chromosomal translocation t (14;20) (q24;p13) is presented: the thymoma and its particular translocation are present in the mother and the two sons of her offspring. The small number of cases do not allow establishing any relation between thymoma and this particular translocation. Concerning genetic counseling, an annual thoracic radiography is necessary for all the other family members, carriers or not of the translocation.
Deminatti
M M
MM
Service de Génétique Humaine et Pathologie Foetale, Faculté de Médecine, Lille, France.
Ribet
M
M
Gosselin
B
B
Bauters
F
F
Mencier
E
E
Savary
J B
JB
Lai
J L
JL
Vasseur
F
F
Morel
P
P
Bisiau-Leconte
S
S
D000328:Adult; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002883:Chromosomes, Human, Pair 14 / Q000648:ultrastructure*; D002890:Chromosomes, Human, Pair 20 / Q000648:ultrastructure*; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D011859:Radiography; D013945:Thymoma / Q000000981:diagnostic imaging / Q000235:genetics*; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics*; D014178:Translocation, Genetic
Thymome familial et translocation t (14;20) (q24;p13).