[Cytologic response of the irradiated vagina to estriol succinate].
The vaginal response to estriol succinate was studied in 40 oncogynecological patients, 20 with irradiation (study group) and 20 without irradiation (control group). Both groups had artificial established menopause at the beginning of the treatment. The previous clinical and cytological patterns to estrogen therapy were more severe in the irradiated group; they presented the highest degree of vaginal atrophy which was related to the type and therapeutic dose used. Response of the study group to a continuous 4 mg of estriol as well as the control group, both has a positive effect in vaginal cytology and alleviates postmenopausal symptoms and improve the quality of life.
Cabrera
J
J
Departamento de Obstetricia y Ginecología, Facultad de Medicina Universidad de Concepción, Hospital Guillermo Grant Benavente.
Canahuate
E
E
del Campo
S L
SL
Poloni
O
O
Ramírez
S I
SI
D000328:Adult; D001284:Atrophy / Q000188:drug therapy; D004964:Estriol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007989:Libido / Q000502:physiology; D008875:Middle Aged; D011446:Prospective Studies; D011832:Radiation Injuries / Q000188:drug therapy*; D014621:Vagina / Q000473:pathology / Q000528:radiation effects*
D004964:Estriol
Respuesta citológica de la vagina irradiada al succinato de estriol.