title: Trimetrexate: a critical appraisal of the phase II clinical trial experience: evidence of drug discovery-clinical development disjunction.
authors.affiliation: Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana 46285.
authors.forename: D E
authors.initials: DE
authors.lastname: Seitz
mesh_terms: D000818:Animals; D017322:Clinical Trials, Phase II as Topic; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D000882:Haplorhini; D006801:Humans; D015337:Multicenter Studies as Topic; D009369:Neoplasms / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000188:drug therapy; D016597:Trimetrexate / Q000627:therapeutic use*
chemical_list: D016597:Trimetrexate