Leptospirosis patient with AIDS: the first case reported.
A case of renal icterohemorrhagic leptospirosis involving a patient with acquired immunodeficiency syndrome (AIDS) is reported. Despite the low levels of CD4+ T lymphocytes, the clinical course of leptospirosis was similar to that observed in non-immunodepressed patients, and no worsening of AIDS occurred due to the infection by the spirochete. Serologic conversion was observed in the microscopic agglutination test, with maximum titer of 1:3,200. The patient had positive urine cultures for Leptospira interrogans for two months, whereas blood cultures were negative.
Neves
E de S
Ede S
Hospital Evandro Chagas, Department of Bacteriology, Instituto Oswaldo Cruz/Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Pereira
M M
MM
Galhardo
M C
MC
Caroli
A
A
Andrade
J
J
Morgado
M G
MG
Mendes
R P
RP
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D017809:Fatal Outcome; D015497:HIV-1; D006801:Humans; D007921:Leptospira interrogans / Q000302:isolation & purification; D008297:Male; D051437:Renal Insufficiency / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D014895:Weil Disease / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology