Changes of certain biochemical values during whole-body exposures of rats to doses of 50, 100 and 250 Gy.
In the course of the postirradiation syndrome, changes of concentrations of certain components and of activities of certain enzymes occur in the blood serum. The data available in the literature concern doses lower than 10 Gy. In the present work, changes were studied of concentrations of mineral components, total proteins, glucose, creatinine and bilirubin and activities of liver transaminases, acid prostatic and alkaline phosphatases up to 24 hours after the whole body exposures of rats to doses of 50, 100 and 250 Gy of ionizing radiation. The changes observed--enhanced kalemia and activity of aspartate aminotransferase, particularly after the highest radiation dose used, and changes of the glycaemia (early increase with a subsequent considerable decrease)--support the assumptions based on the former results known from the literature.
Navrátil
L
L
Institute of Biophysics, 1st Medical Faculty, Charles University, Prague, Czech Republic.
Polívková
J
J
Zich
M
M
D000818:Animals; D001769:Blood / Q000528:radiation effects*; D001774:Blood Chemical Analysis; D005260:Female; D011829:Radiation Dosage; D051381:Rats; D017208:Rats, Wistar; D014916:Whole-Body Irradiation