title: [Retrospective analysis of secondary failure of oral hypoglycemic drugs in patients with diabetes type II].
abstract: The analysis of the incidence and risk factors of oral antidiabetic drugs secondary failure (sf) in type II diabetic patients was carried out in the study. The population of 1262 patients who felt into diabetes between 1980 and 1984 year from Zabrze area was analyzed retrospectively. The analysis was done in relation to 1989 year (after 10 year of the observation). In 194 (15%) of patients secondary failure was diagnosed. Sf appeared in 150 (17%) women and 44 (11%) men (p < 0.005). Multi factor analysis confirmed the higher susceptibility of females to the appearance of sf. Analysis also showed that significant risk factor of sf is the diagnosis of diabetes in 6th life decade in the patients with normal body mass. The percentage of sf varied between 5.1% and 19.5%. Performed analysis showed the higher sf incidence in female group and the influence of age at the moment of diagnosis in non obese patient son the appearance of sf.
authors.affiliation: Katedry i Kliniki Chorób Wewnetrznych i Zawodowych Slaskiej Akademii Medycznej.
authors.forename: K
authors.initials: K
authors.lastname: Strojek
authors.forename: F
authors.initials: F
authors.lastname: Pietraszek
authors.forename: W
authors.initials: W
authors.lastname: Pokrzywnicki
authors.forename: W
authors.initials: W
authors.lastname: Grzeszczak
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D017211:Treatment Failure
chemical_list: D007004:Hypoglycemic Agents
vernacular_title: Retrospektywna analiza wtórnej nieskuteczności doustnych leków hipoglikemizujacych u chorych na cukrzyce typu II.