[Sorbed animal immunoglobulins--a reserve for increasing the output of therapeutic antitoxic and diagnostic sera].
Conditions for the desorption of immunoglobulins from the surface of blood cells of animals used for the production of antitoxic therapeutic and diagnostic sera have been established. The possibility of obtaining, in principle, additional amounts of immunoglobulins and specific antibodies (in comparison with their initial content in sera) without increasing the number of producer animals has been demonstrated. The possibility of using desorbed immunoglobulins and specific antibodies in the production of therapeutic and diagnostic immunobiological preparations is discussed.
Pershin
B B
BB
Kuz'min
S N
SN
Filatov
N N
NN
D000327:Adsorption; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood / Q000302:isolation & purification; D000918:Antibody Specificity; D000992:Antitoxins / Q000097:blood / Q000302:isolation & purification* / Q000627:therapeutic use; D001886:Bordetella pertussis / Q000276:immunology; D002021:Buffers; D003017:Clostridium tetani / Q000276:immunology; D003353:Corynebacterium diphtheriae / Q000276:immunology; D006736:Horses; D006863:Hydrogen-Ion Concentration; D007106:Immune Sera / Q000097:blood / Q000302:isolation & purification*; D007136:Immunoglobulins / Q000097:blood / Q000302:isolation & purification* / Q000627:therapeutic use; D011817:Rabbits; D013696:Temperature
D000907:Antibodies, Bacterial; D000992:Antitoxins; D002021:Buffers; D007106:Immune Sera; D007136:Immunoglobulins
Sorbirovannye immunoglobuliny zhivotnykh--rezerv dlia uvelicheniia vypuska lechebnykh antitoksicheskikh i diagnosticheskikh syvorotok.