title: Isolation and characterization of new chlamydosporol related metabolites of Fusarium chlamydosporum and Fusarium tricinctum.
abstract: Fusarium chlamydosporum strain T-826 isolated from corn in the USA produced chlamydosporol and two analogs which have been identified by various spectroscopic techniques as: 7,8-dihydro-5-hydroxy-4-methoxy-trans-7,8-dimethyl-2H,5H-pyrano(4, 3-b)pyran-2-one (or isochlamydosporol) and 4-methoxy-5-hydroxymethyl-6-(3-butan-2-ol)-2H-pyran-2-one (or chlamydospordiol). Chlamydosporol (compound a + b) chlamydospordiol (compound c) and isochlamydosporol (compound d) were produced together (up to 6000 micrograms/g) by 3 out of 11 isolates of F. chlamydosporum and by 3 out of 24 isolates of F. tricinctum from various substrates and geographic origin. Three isolates of F. chlamydosporum and one isolate of F. tricinctum produced only chlamydospordiol and 2 isolates of F. tricinctum produced chlamydosporol (a + b), and chlamydospordiol (c).
authors.affiliation: Istituto Tossine e Micotossine da parassiti vegetali, CNR, Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Solfrizzo
authors.forename: A
authors.initials: A
authors.lastname: Visconti
authors.forename: M E
authors.initials: ME
authors.lastname: Savard
authors.forename: B A
authors.initials: BA
authors.lastname: Blackwell
authors.forename: P E
authors.initials: PE
authors.lastname: Nelson
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005670:Fusarium / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009183:Mycotoxins / Q000096:biosynthesis*; D011753:Pyrones / Q000378:metabolism*; D013045:Species Specificity; D013053:Spectrophotometry; D003313:Zea mays / Q000382:microbiology
chemical_list: D009183:Mycotoxins; C090739:O-methylisochlamydosporol; D011753:Pyrones; C065449:chlamydosporal; C090737:isochlamydosporol; C090738:chlamydospordiol