title: Post-translational protein import and folding.
abstract: Significant advances have been made over the past year in analyzing the membrane machineries for the post-translational export of proteins in bacteria and for the import of proteins into mitochondria. Another important development is the identification in mitochondria of homologs of the bacterial heat-shock proteins DnaJ and GrpE, which function together with Hsp70 in membrane translocation and folding of imported proteins. A number of gene products involved in peroxisomal protein uptake have been identified, which are now awaiting biochemical analysis.
authors.affiliation: Howard Hughes Medical Institute, New York.
authors.forename: J
authors.initials: J
authors.lastname: Höhfeld
authors.forename: F U
authors.initials: FU
authors.lastname: Hartl
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism*; D001692:Biological Transport / Q000502:physiology; D002736:Chloroplasts / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D018832:Molecular Chaperones / Q000378:metabolism; D017510:Protein Folding; D011499:Protein Processing, Post-Translational
chemical_list: D001426:Bacterial Proteins; D018832:Molecular Chaperones