title: [Glucose tolerance and insulin secretion in patients with hyperthyroidism. Pathogenesis of disturbances and therapeutic consequences].
abstract: Abnormalities of carbohydrate metabolism have been frequently reported in hyperthyroid patients. Disturbed glucose tolerance might be due to increased hepatic glucose production, altered insulin metabolism, increased response to beta-adrenergic stimuli and elevated plasma FFA levels. These disturbances very often disappear when remission of thyrotoxicosis is attained during-treatment with thyrostatic drugs. Non-selective or selective beta 1-adrenoceptor blocking agents does not impair the glucose stimulated insulin secretion or the carbohydrate tolerance and impaired glucose tolerance disappear when glycolytic blockade is attained.
authors.affiliation: I Kliniki Chorób Wewnetrznych Slaskiej AM. Katowicach.
authors.forename: T
authors.initials: T
authors.lastname: Gasińska
authors.forename: L
authors.initials: L
authors.lastname: Wawrzyniak
mesh_terms: D005947:Glucose / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology / Q000378:metabolism* / Q000628:therapy; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion
chemical_list: D007328:Insulin; D005947:Glucose
vernacular_title: Przemiana weglowodanowa i wydzieleni insuliny u chorych z nadczynnościa tarczycy. Patogeneza zaburzeń i konsekwencje terapeutyczne.