Budd-Chiari syndrome associated with antiphospholipid antibodies in a child: report of a case and review of the literature.
Budd-Chiari syndrome, hypertension, and thrombocytopenia developed in a 6-year-old girl as manifestations of primary antiphospholipid antibody syndrome (APS). She improved with systemic corticosteroid and anticoagulation therapy. Anticardiolipin antibodies were found in the patient, her mother and 3 siblings, suggesting the importance of genetic factors. The clinical features of an APS in children is reviewed.
Saca
L F
LF
Department of Pediatrics, Los Angeles County, School of Medicine, CA.
Szer
I S
IS
Henar
E
E
Nanjundiah
P
P
Haddad
Z H
ZH
Quismorio
F P
FP
D015746:Abdominal Pain / Q000209:etiology; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis; D006502:Budd-Chiari Syndrome / Q000209:etiology*; D002648:Child; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007084:Iliac Vein; D013927:Thrombosis / Q000209:etiology