title: Breast arterial calcification: association with coronary artery disease. Work in progress.
abstract: OBJECTIVE
  To assess the association between mammographically detected breast arterial calcification (BAC) and coronary artery disease (CAD) and diabetes mellitus (DM).
  
  
  METHODS
  The records of 182 women (aged 39-92 years) who underwent both mammography and coronary arteriography were retrospectively reviewed to determine BAC, CAD, and DM status.
  
  
  RESULTS
  For women aged less than 59 years (under-59 group) (n = 54), nearly all women with BAC (n = 8) had CAD (n = 7) and also had DM (n = 6). For this group, the positive predictive value of BAC for CAD was 0.88 and the negative predictive value was 0.65 (chi 2 = 7.7, P < .05). DM was a confounding variable. The positive predictive value of DM for CAD increased from 0.62 when BAC was absent to 1.00 when BAC was present (standard error of difference, .22; P < .10). No significant association between BAC and CAD was found for women aged 59 years and older (n = 128).
  
  
  CONCLUSIONS
  BAC in women aged less than 59 years may indicate an additional risk factor for CAD, particularly in diabetic patients.
authors.affiliation: Department of Radiology, Geisinger Medical Center, Danville, PA 17822-2007.
authors.forename: A C
authors.initials: AC
authors.lastname: Moshyedi
authors.forename: A H
authors.initials: AH
authors.lastname: Puthawala
authors.forename: R J
authors.initials: RJ
authors.lastname: Kurland
authors.forename: D H
authors.initials: DH
authors.lastname: O'Leary
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000098:blood supply*; D001941:Breast Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002114:Calcinosis / Q000150:complications* / Q000000981:diagnostic imaging; D003327:Coronary Disease / Q000175:diagnosis / Q000209:etiology*; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D011859:Radiography; D012189:Retrospective Studies; D012307:Risk Factors