title: Two cases of Caroli's disease: diagnosis and management.
abstract: Caroli's disease is an uncommon congenital malformation involving the intrahepatic bile ducts. This paper reports two cases presenting with biliary tract infection. Diagnosis was established by non-invasive imaging and cholangiography. The infecting organisms were cultured from bile obtained by percutaneous aspiration and the results were used to direct antimicrobial therapy. The role of antibiotics and other management options in preventing recurrent infection is discussed.
authors.affiliation: Department of Gastroenterology, Christchurch Hospital, New Zeland.
authors.forename: M J
authors.initials: MJ
authors.lastname: Burt
authors.forename: S T
authors.initials: ST
authors.lastname: Chambers
authors.forename: B A
authors.initials: BA
authors.lastname: Chapman
authors.forename: M F
authors.initials: MF
authors.lastname: Strack
authors.forename: W D
authors.initials: WD
authors.lastname: Troughton
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D001653:Bile Ducts, Intrahepatic / Q000002:abnormalities; D016767:Caroli Disease / Q000150:complications / Q000000981:diagnostic imaging*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002761:Cholangitis / Q000188:drug therapy / Q000209:etiology; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy / Q000209:etiology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D008795:Metronidazole; D000658:Amoxicillin