[Long-term results of the treatment of diffuse systemic scleroderma with interferon-gamma].
There are very few drugs effective in the treatment of diffuse scleroderma and therefore we conducted an open study with gamma interferon. Among 20 diffuse scleroderma, evolving since less than 3 years, an improvement was observed in 8 patients. There was no serious side effect. Survival of these 20 patients was 85% at 5 years.
Blétry
O
O
Service de médecine interne, hôpital de la Pitié, Paris.
Laraki
R
R
Cabane
J
J
Francès
C
C
Piette
J C
JC
Soubrier
M
M
Wechsler
B
B
de Gennes
C
C
Valat
C
C
Cosserat
J
J
D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000628:therapy*; D013997:Time Factors
D007371:Interferon-gamma
Résultats à long terme du traitement des sclérodermies systémiques diffuses par l'interféron gamma.