title: [Changes of immune and non-specific reactivity in patients with chronic suppurative obstructive bronchitis in comprehensive treatment with thymogen].
abstract: A total of 33 patients with chronic pyoobstructive bronchitis with immunological disorders (of T-cell and other links) and nonspecific responsiveness. The use of thymogen in multi-modality treatment contributed to normalization of T-cell immunity (increases in E-rosette formation, responses of blast cell transformation to phytohemagglutinin, Tx/Tc ratio), as well as nonspecific responsiveness parameters (C3c, NBT-test, natural killers), resulting in higher clinical efficacy.
authors.forename: N V
authors.initials: NV
authors.lastname: Litvinova
authors.forename: V V
authors.initials: VV
authors.lastname: Eremeev
authors.forename: Z P
authors.initials: ZP
authors.lastname: Abramova
authors.forename: N V
authors.initials: NV
authors.lastname: Kulikovskaia
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Gergert
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use*; D001402:B-Lymphocytes / Q000187:drug effects; D001991:Bronchitis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D004151:Dipeptides; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D008173:Lung Diseases, Obstructive / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D010455:Peptides / Q000494:pharmacology / Q000627:therapeutic use*; D013492:Suppuration; D013601:T-Lymphocytes / Q000187:drug effects
chemical_list: D000276:Adjuvants, Immunologic; D004151:Dipeptides; D010455:Peptides; C060736:thymogen
vernacular_title: Izmeneniia immunologicheskoĭ i nespetsificheskoĭ reaktivnosti u bolńykh khronicheskim gnoĭno-obstruktivnym bronkhitom pri kompleksnom lechenii s primeneniem timogena.