[Detection and clinical significance of PPD-IgG antibody in cerebrospinal fluid by ABC-ELISA method].
PPD-IgG antibody in cerebrospinal fluid (CSF) of 55 patients with tuberculous meningitis (TBM) and 37 patients with non-TBM was determined by ABC-ELISA method, and compared with ELISA. The positive rate of ABC-ELISA and ELISA was 96.4% and 83.6% respectively (P < 0.05). Specificity of two methods was 97.3%. Meanwhile the positive rate in CSF (96.4%) is markedly higher than that in sera (85.5%) (P < 0.05). The results showed that this method can be as a supporting method for diagnosis of TBM.
Song
L B
LB
First Hospital of Tianmen City.
Han
M H
MH
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000134:cerebrospinal fluid*; D001426:Bacterial Proteins; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid*; D007223:Infant; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000276:immunology*; D014373:Tuberculin / Q000276:immunology*; D014390:Tuberculosis, Meningeal / Q000134:cerebrospinal fluid / Q000175:diagnosis*
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D007074:Immunoglobulin G; D010455:Peptides; D014373:Tuberculin; C009610:tuberculin-active protein, Mycobacterium