[Observation on the action of extractum semen Persicae on anti-fibrosis of liver].
It was observed that Extractum Semen Persicae acted obviously on hepatic fibrosis induced by CCl4. Through promoting the degradation of collagens type I, II, IV, VI and fibronectin, ESP has proved helpful in markedly reducing the fibrous septa composed of both collagenous and reticular fibers as well as in repairing the structure of hepatic tissues.
Xu
L M
LM
Liver Diseases Research Center, Shanghai Academy of Traditional Chinese Medicine.
Liu
P
P
Liu
C
C
Hong
J H
JH
Lu
G
G
Xue
H M
HM
Zhu
J L
JL
Hu
Y Y
YY
D000678:Amygdalin / Q000494:pharmacology*; D000818:Animals; D002252:Carbon Tetrachloride Poisoning; D003094:Collagen / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005353:Fibronectins / Q000378:metabolism; D007150:Immunohistochemistry; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008103:Liver Cirrhosis / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal; D005353:Fibronectins; D000678:Amygdalin; D003094:Collagen