title: [Is chorionic biopsy a dangerous and outdated method?].
abstract: The authors evaluated the risk of chorion biopsy used within the framework of prenatal diagnosis of the foetus. The incidence of abortions following transabdominal CVS (0.6%) did not differ from abortions after amniocentesis in the second trimester (0.5%). In a group of 1002 diagnostic biopsies of the chorion the authors did not record in the born infants reduction deformities of the extremities. Chorion biopsies were performed in 98% between the 10th and 12th week of gestation. The incidence of mosaicism--1.59%--was not significantly higher than reported in the literature. The authors recommend: to increase the size of the sample of chorion tissue by the use of a manual aspirator, the use of a 30 ml plastic syringe or the double needle method. They consider CVS a suitable method which serves the diagnosis of IUGR and the prenatal diagnosis of the foetus before the 20th week of gestation when cordocentesis involves risk.
authors.affiliation: I. gynek.-porod. klinika 1. LF UK, Praha.
authors.forename: Z
authors.initials: Z
authors.lastname: Hájek
authors.forename: E
authors.initials: E
authors.lastname: Kulovaný
authors.forename: M
authors.initials: M
authors.lastname: Macek
authors.forename: D
authors.initials: D
authors.lastname: Stejskal
mesh_terms: D000022:Abortion, Spontaneous / Q000209:etiology; D000649:Amniocentesis / Q000009:adverse effects; D015193:Chorionic Villi Sampling / Q000009:adverse effects*; D000013:Congenital Abnormalities / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy
vernacular_title: Je choriová biopsie nebezpecnou a prekonanou metodou?