title: Carcinoid tumor of the middle ear.
abstract: Carcinoid tumor of the middle ear is a very rare benign neoplasm, which may be mistaken for a malignant tumor. We present two new cases together with a review of 28 previously reported cases. Nearly all patients had progressive hearing loss, most often of the conductive type. About half of the patients complained of tinnitus and fullness of the ear. The typical otoscopic picture was erythema or lateral bulging of the tympanic membrane, which was intact in most patients. The tumor was most often localized to the middle ear with varying degree of extensions into neighboring areas. It often encapsulated the ossicles, which sometimes were eroded. Systemic symptoms were only reported in two cases. The tumor is clinically benign and total excision of the tumor and affected ossicles is an adequate treatment. The correct diagnosis, which should be considered in case of any adenomatous tumor of the middle ear, requires immunohistochemical and ultrastructural procedures.
authors.affiliation: Department of Otolaryngology, Glostrup Hospital, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Nyrop
authors.forename: B
authors.initials: B
authors.lastname: Guldhammer Skov
authors.forename: M
authors.initials: M
authors.lastname: Katholm
authors.forename: H W
authors.initials: HW
authors.lastname: Nielsen
mesh_terms: D000328:Adult; D002276:Carcinoid Tumor / Q000150:complications / Q000473:pathology* / Q000601:surgery; D002781:Cholesteatoma / Q000473:pathology; D003937:Diagnosis, Differential; D004428:Ear Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D004432:Ear, Middle / Q000473:pathology* / Q000601:surgery; D006314:Hearing Loss, Conductive / Q000209:etiology; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged