Recognition of Dermabacter hominis, formerly CDC fermentative coryneform group 3 and group 5, as a potential human pathogen.
Thirty strains of fermentative coryneform-like bacteria designated CDC fermentative coryneform group 3 and coryneform group 5 were compared biochemically by cellular fatty acid analysis and by DNA relatedness with the type strain of Dermabacter hominis, ATCC 49369. DNA from 22 strains of both CDC groups showed 69 to 96% relatedness (hydroxyapatite method) to labeled DNA from ATCC 49369 and to DNA from CDC group 3 strain G4964, and the strains are considered to belong to D. hominis. The remaining eight strains were genetically but not phenotypically differentiable from D. hominis. They were genetically heterogeneous, but hybridization results indicated that they probably belong to the genus Dermabacter. Thirteen of the 22 D. hominis strains and all 8 of the other Dermabacter strains had been isolated from blood, which indicates the pathogenic potential of this species and genus.
Gruner
E
E
Institute for Medical Microbiology, University of Zurich, Switzerland.
Steigerwalt
A G
AG
Hollis
D G
DG
Weyant
R S
RS
Weaver
R E
RE
Moss
C W
CW
Daneshvar
M
M
Brenner
D J
DJ
D000192:Actinomycetales / Q000145:classification* / Q000201:enzymology / Q000472:pathogenicity*; D000193:Actinomycetales Infections / Q000382:microbiology; D000328:Adult; D000368:Aged; D015373:Bacterial Typing Techniques; D002487:Centers for Disease Control and Prevention, U.S.; D004269:DNA, Bacterial / Q000235:genetics; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D014481:United States
D004269:DNA, Bacterial; D005227:Fatty Acids