[Binswanger's disease and its relationship with vascular risk factors].
BACKGROUND
Lesions in the periventricular white matter are a quite common neuroradiological finding in older patients. They are called leukoaraiosis and can be associated to several syndromes.


OBJECTIVE
To study the relation between leukoaraiosis and the different vascular risk factors that can be involved in its development.


METHODS
Fifty consecutive patients with leukoaraiosis in CT scan were included as well as fifty age and sex-matched controls; all of them belonged to the same population. Previously vascular risk factors were defined according to strict criteria.


RESULTS
The commonest vascular risk factor was arterial hypertension, in second place previous cerebrovascular accidents and in third place heart diseases. There was a very significant difference for hypertension in the univariant analysis, which was subsequently confirmed in the multivariant analysis.


CONCLUSIONS
The vascular risk factor most strongly associated to leukoaraiosis was arterial hypertension followed by cerebrovascular disease and heart diseases. The remaining of the analysed factors had a insignificant prediction power.
Modrego Pardo
P J
PJ
Sección de Neurología del Hospital de la Seguridad Social de Jerez de la Frontera.
Pérez Trullen
J M
JM
D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000150:complications*; D016022:Case-Control Studies; D015140:Dementia, Vascular / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors
Leucoaraiosis y su relación con los factores de riesgo vascular.