title: Agenesis of corpus callosum and dementia of the Alzheimer's type: a review and case report.
abstract: This paper describes a previously sufficiently functioning 57 year old man who presented with a recent onset of frontal behaviour. Partial agenesis of corpus callosum was an incidental finding on a computerized tomography scan. The EEG was within normal limits and neuropsychological testing did not reveal any interhemispheric disconnection. A SPECT-Scan revealed bilateral hypoperfusion, consistent with Alzheimer's dementia. Normal functioning up to 50 years of age and a later manifestation of Alzheimer's disease along with agenesis of carpus callosum is of clinical interest as such an association has not been published.
authors.affiliation: Harbor-UCLA Medical Center, Torrance.
authors.forename: N
authors.initials: N
authors.lastname: Rasgon
authors.forename: J
authors.initials: J
authors.lastname: Ananth
authors.forename: I
authors.initials: I
authors.lastname: Mena
authors.forename: B
authors.initials: B
authors.lastname: Krout
authors.forename: K
authors.initials: K
authors.lastname: Boone
mesh_terms: D061085:Agenesis of Corpus Callosum; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology; D002540:Cerebral Cortex / Q000098:blood supply; D004292:Dominance, Cerebral / Q000502:physiology; D004569:Electroencephalography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012039:Regional Blood Flow / Q000502:physiology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed