title: Clinical evaluation of Tc-99m cystine. A new renal radiopharmaceutical.
abstract: Tc-99m cystine has been proved to be a good renal agent in animals. Its clinical evaluation has not been reported. In this study, Tc-99m cystine is used for evaluation of renal function in normal subjects and patients with chronic renal failure as well as in renal transplant patients. The results are compared with similar studies using Tc-99m DTPA and Tc-99m GHA. The clearance values also are compared with I-131 OIH. The results show that Tc-99m cystine has good radiopharmaceutical characteristics suitable for evaluation of both renal function as well as morphology.
authors.affiliation: Department of Nuclear Medicine, Indian Institute of Chemical Biology, Calcutta.
authors.forename: M
authors.initials: M
authors.lastname: Misra
authors.forename: B K
authors.initials: BK
authors.lastname: Das
authors.forename: S
authors.initials: S
authors.lastname: Gambhir
authors.forename: B R
authors.initials: BR
authors.lastname: Mittal
authors.forename: A B
authors.initials: AB
authors.lastname: Sewatkar
authors.forename: S
authors.initials: S
authors.lastname: Ghosh
authors.forename: S N
authors.initials: SN
authors.lastname: Banerjee
mesh_terms: D003553:Cystine / Q000031:analogs & derivatives*; D006801:Humans; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid; D007668:Kidney / Q000000981:diagnostic imaging; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging*; D016030:Kidney Transplantation / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D011866:Radioisotope Renography; D013400:Sugar Acids; D016284:Technetium Tc 99m Pentetate
chemical_list: D007457:Iodine Radioisotopes; D015609:Organotechnetium Compounds; D013400:Sugar Acids; C060718:technetium Tc 99m cystine; D007465:Iodohippuric Acid; D003553:Cystine; C100014:technetium Tc 99m gluceptate; D016284:Technetium Tc 99m Pentetate