title: Tolerance and absorption of lactose from milk and yogurt during short-bowel syndrome in humans.
abstract: This study aimed to compare the absorption and tolerance of 20-g lactose loads as milk and yogurt in 17 patients with short-bowel syndrome with either a terminal jejunostomy (group A, n = 6) or a jejunocolic anastomosis (group B, n = 11). Records and measurements during the 8 h after the meals included fecal weight, symptoms, lactose and hexose flow rates in stomal effluents (group A), and breath-hydrogen excretion (group B). In group A lactose was better absorbed in the form of yogurt than in the form of milk (mean +/- SE: 76 +/- 6% vs 50 +/- 9%, P < 0.05), whereas no significant difference could be detected by using the breath-hydrogen test in group B. The excellent tolerance to 20 g lactose from milk and yogurt suggests that lactose should not be excluded from the diet of these subjects.
authors.affiliation: INSERM U 290, Fonctions Intestinales, Métabolisme et Nutrition, Hôpital Saint-Lazare, Paris.
authors.forename: E
authors.initials: E
authors.lastname: Arrigoni
authors.forename: P
authors.initials: P
authors.lastname: Marteau
authors.forename: F
authors.initials: F
authors.lastname: Briet
authors.forename: P
authors.initials: P
authors.lastname: Pochart
authors.forename: J C
authors.initials: JC
authors.lastname: Rambaud
authors.forename: B
authors.initials: B
authors.lastname: Messing
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001944:Breath Tests; D005243:Feces; D005260:Female; D006801:Humans; D006859:Hydrogen / Q000378:metabolism; D007408:Intestinal Absorption; D043322:Lactase; D007785:Lactose / Q000378:metabolism*; D007787:Lactose Intolerance; D008297:Male; D008875:Middle Aged; D008892:Milk; D012778:Short Bowel Syndrome / Q000378:metabolism*; D015014:Yogurt; D001616:beta-Galactosidase / Q000378:metabolism
chemical_list: D006859:Hydrogen; D043322:Lactase; D001616:beta-Galactosidase; D007785:Lactose