title: [Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, during use of the antidepressant fluoxetine].
abstract: In a 78-year-old female with hyponatraemia, the syndrome of inappropriate ADH secretion as a side effect of fluoxetine, a relatively new antidepressive drug, was tentatively diagnosed. In the literature 14 cases of this adverse reaction have been described. One should be careful when prescribing fluoxetine to elderly persons, notably when a diuretic is prescribed as well.
authors.affiliation: Rode Kruis Ziekenhuis, afd. Interne Geneeskunde, Beverwijk.
authors.forename: W L
authors.initials: WL
authors.lastname: ten Holt
authors.forename: C H
authors.initials: CH
authors.lastname: Klaassen
authors.forename: G
authors.initials: G
authors.lastname: Schrijver
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005473:Fluoxetine / Q000009:adverse effects*; D006801:Humans; D007010:Hyponatremia / Q000209:etiology*; D007177:Inappropriate ADH Syndrome / Q000139:chemically induced* / Q000150:complications*; D008297:Male; D008875:Middle Aged
chemical_list: D005473:Fluoxetine
vernacular_title: Ernstige hyponatriëmie, mogelijk door inadequate antidiuretisch-hormoonsecretie, bij gebruik van het antidepressivum fluoxetine.