title: [The characteristics of iron metabolism in B12-deficient anemias (an evaluation of the functional status of megaloblastic erythropoiesis)].
abstract: The review of the literature data and the evidence obtained on 85 own patients with B12-deficiency anemia concerning iron metabolism underlie 3 variants proposed by the authors: pronounced manifestations of secondary sideroachresia before B12 therapy, utilization iron deficiency upon B12 introduction, dimorphic anemia (development of megaloblastic erythropoiesis in prior iron deficiency). The causes of megaloblastic erythropoiesis incompetence (slow rate, hemolytic component, secondary sideroachresia) are discussed.
authors.forename: G B
authors.initials: GB
authors.lastname: Berliner
authors.forename: L M
authors.initials: LM
authors.lastname: Kheĭfets
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000188:drug therapy; D000749:Anemia, Megaloblastic / Q000097:blood* / Q000188:drug therapy; D004920:Erythropoiesis / Q000187:drug effects; D005260:Female; D006801:Humans; D007501:Iron / Q000097:blood*; D000090463:Iron Deficiencies; D008297:Male; D008534:Megaloblasts / Q000187:drug effects / Q000378:metabolism*; D008875:Middle Aged; D014805:Vitamin B 12 / Q000627:therapeutic use; D014806:Vitamin B 12 Deficiency / Q000097:blood* / Q000188:drug therapy
chemical_list: D007501:Iron; D014805:Vitamin B 12
vernacular_title: Osobennosti obmena zheleza pri B12-defitsitnykh anemiiakh (k otsenke funktsional'nogo sostoianiia megaloblastnogo éritropoéza).