[Erythroclastic bone marrow clusters and prognostication of the character of the course of acute lymphoblastic leukemia].
A new variety of bone marrow clusters was revealed, that is formed of mature red cells by bone-marrow macrophages and other myelokaryocytes containing hydrolytic enzymes. Exocytotic lysis of the red cells, contained in these clusters, by cluster-forming cells is frequently observed. This fact permitted calling this variety 'erythroclastic clusters'. The number of clusters, in which exocytotic red cell lysis occurs, was found to grow fourfold in the active phase of acute lymphoblastic leukemia; this fact may be used for the early diagnosis of the disease or for prediction of its recurrence.
Bel'chenko
D I
DI
D001853:Bone Marrow / Q000473:pathology*; D001856:Bone Marrow Examination; D002648:Child; D005089:Exocytosis; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis
Eritroklazicheskie kostnomozgovye klastery i prognozirovanie kharaktera techeniia ostrogo limfoblastnogo leĭkoza.