title: Acute disseminated encephalomyelitis presenting as a neurodegenerative disease in infancy.
abstract: An infant with acute demyelinating encephalomyelitis resulting from California virus infection presented with a neurodegenerative clinical picture. The clinical course was complicated by infantile spasms which responded to treatment with corticotropin. Acute demyelinating encephalomyelitis should be included in the diagnostic evaluation of patients who present with subacute regression of developmental milestones.
authors.affiliation: Department of Neurology, Indiana University School of Medicine, Indianapolis.
authors.forename: B P
authors.initials: BP
authors.lastname: Garg
authors.forename: M B
authors.initials: MB
authors.lastname: Kleiman
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage; D001921:Brain / Q000473:pathology; D003131:Combined Modality Therapy; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000534:rehabilitation; D003937:Diagnosis, Differential; D004569:Electroencephalography / Q000187:drug effects; D004670:Encephalitis, California / Q000175:diagnosis* / Q000534:rehabilitation; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination / Q000187:drug effects; D026741:Physical Therapy Modalities; D013036:Spasms, Infantile / Q000175:diagnosis / Q000534:rehabilitation
chemical_list: D000324:Adrenocorticotropic Hormone