title: [Long-term results of the treatment of diffuse systemic scleroderma with interferon-gamma].
abstract: There are very few drugs effective in the treatment of diffuse scleroderma and therefore we conducted an open study with gamma interferon. Among 20 diffuse scleroderma, evolving since less than 3 years, an improvement was observed in 8 patients. There was no serious side effect. Survival of these 20 patients was 85% at 5 years.
authors.affiliation: Service de médecine interne, hôpital de la Pitié, Paris.
authors.forename: O
authors.initials: O
authors.lastname: Blétry
authors.forename: R
authors.initials: R
authors.lastname: Laraki
authors.forename: J
authors.initials: J
authors.lastname: Cabane
authors.forename: C
authors.initials: C
authors.lastname: Francès
authors.forename: J C
authors.initials: JC
authors.lastname: Piette
authors.forename: M
authors.initials: M
authors.lastname: Soubrier
authors.forename: B
authors.initials: B
authors.lastname: Wechsler
authors.forename: C
authors.initials: C
authors.lastname: de Gennes
authors.forename: C
authors.initials: C
authors.lastname: Valat
authors.forename: J
authors.initials: J
authors.lastname: Cosserat
mesh_terms: D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000628:therapy*; D013997:Time Factors
chemical_list: D007371:Interferon-gamma
vernacular_title: Résultats à long terme du traitement des sclérodermies systémiques diffuses par l'interféron gamma.