title: Pulsatile flow and simple flow control method during weaning period in centrifugal pump: toward more expanded usage in open heart surgery.
abstract: To expand the usage of the centrifugal pump (CP) in open heart surgery, we performed two studies. In the first, we evaluated pulsatile flow in the CP. In vitro pump performance of the Terumo Capiox pump (TCP) and the Sarns Delphin pump (SDP) and increase of free hemoglobin (mg/dl) after driving 6 h were investigated using bovine blood. A roller pump (RP) was used as a comparison. Equally effective pulsatile flow was obtained in both CPs. Hemolysis was less severe in TCP (120 mg/dl) than SDP (210 mg/dl) and RP (320 mg/dl). In the second study, we evaluated a simple flow control method. Flow rate was easily controlled with step-wise clamping of 3-pronged tubing (Triple-flow) without changing rotational speed, regardless of afterload. Fluctuation of flow was much less with this method than with the rotational speed change method. The use of pulsatile flow of TCP, with its minimum increase of hemolysis and the easier flow control method during the weaning process, may expand the usage of CP in open heart surgery.
authors.affiliation: Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College.
authors.forename: H
authors.initials: H
authors.lastname: Nishida
authors.forename: H
authors.initials: H
authors.lastname: Koyanagi
authors.forename: M
authors.initials: M
authors.lastname: Endo
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Oshiyama
authors.forename: C
authors.initials: C
authors.lastname: Nojiri
authors.forename: H
authors.initials: H
authors.lastname: Fukasawa
authors.forename: T
authors.initials: T
authors.lastname: Akutsu
mesh_terms: D000818:Animals; D006348:Cardiac Surgical Procedures; D002417:Cattle; D006353:Heart-Assist Devices / Q000009:adverse effects; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D007430:Intraoperative Care; D008955:Models, Cardiovascular; D008961:Models, Structural; D011673:Pulsatile Flow
chemical_list: D006454:Hemoglobins