title: An osteolytic lesion associated with polyethylene wear debris adjacent to a stable total knee prosthesis.
abstract: Seven years after total knee arthroplasty, a patient with a well-fixed, uncemented femoral component (cobalt-chromium-molybdenum alloy) developed a large cystic lesion in the distal femur adjacent to the femoral component. This lesion contained fibrotic soft tissue, evidence of a foreign-body giant cell reaction, and a large number of polyethylene particles, but no metal wear debris, infection, or malignancy.
authors.affiliation: Grand Rapids Orthopaedic Surgery Residency Program, Michigan.
authors.forename: K R
authors.initials: KR
authors.lastname: Kane
authors.forename: D H
authors.initials: DH
authors.lastname: DeHeer
authors.forename: J D
authors.initials: JD
authors.lastname: Beebe
authors.forename: R
authors.initials: R
authors.lastname: Bereza
mesh_terms: D000368:Aged; D002858:Chromium Alloys; D003343:Corrosion; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging* / Q000473:pathology; D005549:Foreign-Body Reaction / Q000473:pathology; D006801:Humans; D007720:Knee Prosthesis; D010003:Osteoarthritis / Q000601:surgery*; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000209:etiology*; D011095:Polyethylenes; D011859:Radiography
chemical_list: D002858:Chromium Alloys; D011095:Polyethylenes