title: Chromate reductase activity of Enterobacter aerogenes is induced by nitrite.
abstract: A chromate resistant mutant of Enterobacter aerogenes manifested its chromate resistance only under aerobic conditions. Both parent and mutant showed substantial levels of anaerobic chromate reductase activity when grown on glycerol plus fumarate. The chromate reductase was further induced by growth in the presence of nitrite but was repressed by nitrate. The chromate reductase activity paralleled that of the formate-linked nitrite reductase. There was no significant difference in chromate reductase levels between the parent and its chromate resistant mutant, indicating that this enzyme activity is not, in fact responsible for chromate resistance as was suggested previously by others.
authors.affiliation: Department of Microbiology, Southern Illinois University, Carbondale 62901.
authors.forename: D P
authors.initials: DP
authors.lastname: Clark
mesh_terms: D002840:Chromates / Q000378:metabolism* / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004754:Enterobacter / Q000201:enzymology* / Q000235:genetics; D004790:Enzyme Induction / Q000187:drug effects; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects*; D008982:Molybdenum / Q000378:metabolism; D009154:Mutation; D009572:Nitrite Reductases / Q000032:analysis; D009573:Nitrites / Q000494:pharmacology*; D010088:Oxidoreductases / Q000096:biosynthesis*
chemical_list: D002840:Chromates; D009573:Nitrites; C044659:molybdate; D008982:Molybdenum; D010088:Oxidoreductases; D009572:Nitrite Reductases; C063243:chromate reductase