title: [Corticotropic macroadenoma: clinical, hormonal, radiological and immunocytochemical study of 6 cases].
abstract: We report 6 cases of corticotroph macroadenomas which show heterogeneity of clinical and biological features (from Cushing's syndrome to silent adenoma) and heterogeneity of immunocytochemical staining. One patient reported on had skin hyperpigmentation and ACTH hypersecretion without clear abnormal adrenocortical function; we believe that this patient's plasma contained ACTH with very low bioactivity.
authors.affiliation: Service de médecine interne, endocrinologie, hôpital Jean Bernard, Poitiers.
authors.forename: R
authors.initials: R
authors.lastname: Maréchaud
authors.forename: C
authors.initials: C
authors.lastname: Humbert
authors.forename: F
authors.initials: F
authors.lastname: Bonneau
authors.forename: J P
authors.initials: JP
authors.lastname: Saint-André
authors.forename: B
authors.initials: B
authors.lastname: Bataille
authors.forename: S
authors.initials: S
authors.lastname: Fieuzal
authors.forename: C
authors.initials: C
authors.lastname: Prono
authors.forename: P
authors.initials: P
authors.lastname: Vandermarcq
mesh_terms: D000236:Adenoma / Q000175:diagnosis* / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D000324:Adrenocorticotropic Hormone
vernacular_title: Le macroadénome corticotrope: étude clinique, hormonale, radiologique et immunocytochimique de 6 observations.