title: Chromosome rearrangements and human gene mapping.
abstract: The successful mapping of numerous mendelian disorders by chromosome rearrangements turned out to be a key method for positional location of disease genes. We present some personal observations and comments on the interest of cytogenetic studies in human gene mapping.
authors.affiliation: Laboratoire de Génétique Humaine, Centre Régional de transfusion Sanguine, Vandoeuvre-les-Nancy, France.
authors.forename: S
authors.initials: S
authors.lastname: Gilgenkrantz
authors.forename: C
authors.initials: C
authors.lastname: Philippe
authors.forename: M
authors.initials: M
authors.lastname: Chery
mesh_terms: D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D015321:Gene Rearrangement / Q000235:genetics*; D008040:Genetic Linkage; D006801:Humans; D007223:Infant; D014960:X Chromosome / Q000235:genetics