[The role of toxocariasis in the etiology of hypereosinophilic syndrome in children].
Toxocariasis as a helminth zoonatroponosis is very common in dogs in our region, thus the infestation of human population, especially children, is frequent, 59 children with high blood eosinophilia, aged 18 months to 14 years, were examined on toxocariasis by indirect immunofluorescence test, 23 children were positive, with antibody titre 1:20-640. Dominant symptoms and signs were cough, allergic exantemas, lymphadenopathy and leucocytosis. One child had eosinophilic meningitis. Some of these children were addicted to geophagia, particularly those with clinical picture corresponding to toxocariasis. The original antigen for the indirect immunofluorescent antibody assay was made of mice brains previously infected with high dose of toxocara larvae (6000 per mouse). Two or three months later, mice were sacrificed and their brains were fixed and included in paraffin wax. Histological sections were used as antigen for titration of patient's serum samples. Authors conclude that all eosinophilias in children should be examined serologically for toxocariasis.
Lalosević
D
D
Institut za zdravstvenu zastitu majke i deteta, Pasterov zavod, Novi Sad.
Gebauer
E
E
Malenković
M
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000469:parasitology*; D007223:Infant; D014120:Toxocariasis / Q000150:complications*
Udeo toksokarijaze u etiologiji hipereozinofilnog sindroma u dece.