title: Effect of a low molecular weight peptide bound to liver mitochondrial DNA on in vitro DNA duplication.
abstract: Authors tested "in vitro" action of a low molecular weight peptide fraction extracted by mitochondrial DNA from calf liver. The fraction acts upon duplication performed by E. Coli DNA polymerase I on poli dAT dAT template inhibiting chain elongation. The authors hypothesize that a similar role is exerted by this fraction "in vitro" on mitochondrial DNA template.
authors.affiliation: Department of Cell Biology, University of Calabria, Rende, CS.
authors.forename: A
authors.initials: A
authors.lastname: Spena
authors.forename: V
authors.initials: V
authors.lastname: Pedace
authors.forename: C
authors.initials: C
authors.lastname: Covello
authors.forename: T
authors.initials: T
authors.lastname: De Cicco
authors.forename: S
authors.initials: S
authors.lastname: Mazzulla
authors.forename: G
authors.initials: G
authors.lastname: Martino
mesh_terms: D000818:Animals; D002417:Cattle; D004261:DNA Replication / Q000187:drug effects*; D004272:DNA, Mitochondrial / Q000032:analysis*; D008930:Mitochondria, Liver / Q000737:chemistry*; D008970:Molecular Weight; D010455:Peptides / Q000494:pharmacology*
chemical_list: D004272:DNA, Mitochondrial; D010455:Peptides