[The use of monoclonal antibodies for detecting the influenza virus].
The possibilities of using influenza A (Leningrad) 385/80 (H3N2) virus matrix protein-specific FITC-labeled D8 monoclonal antibodies in immunofluorescence assays were investigated. The virus antigen accumulation was detected in chorioallantoic cells of chick embryos. Exhibiting the type-specific properties, the fluorescent antibodies stain the perinuclear space, cytoplasmic membrane, and granular structures in the cytoplasm of infected cells. The haemagglutination test tires in the corresponding specimens were at least 1:16.
Bakova
A A
AA
Brondz
B D
BD
Fedorkina
O A
OA
Gusev
V A
VA
Gordienko
A I
AI
Krivoshein
Iu S
IuS
Krivorutchenko
Iu L
IuL
Prokopenko
T G
TG
Popov
I A
IA
D000818:Animals; D000911:Antibodies, Monoclonal; D002642:Chick Embryo; D005455:Fluorescent Antibody Technique; D006801:Humans; D009980:Influenza A virus / Q000276:immunology*; D007251:Influenza, Human / Q000175:diagnosis; D012680:Sensitivity and Specificity; D014763:Viral Matrix Proteins / Q000276:immunology
D000911:Antibodies, Monoclonal; D014763:Viral Matrix Proteins
Ispol'zovanie monoklonal'nykh antitel dlia vyiavleniia virusa grippa.