[Acute pancreatitis and biological antioxidants].
The values of lipid free--radical oxidation and the effect of various methods of treatment on these processes were studied in 164 patients with acute pancreatitis. Combined use of oil emulsions with agents possessing antioxidation activity (unithiol, tocopherol) produced the best values. Combined therapy promoted normalization of the main parameters characterizing the activity of lipid peroxidation reactions which was attended with reduced concentrations of pancreatic enzymes and increased concentration of beta-lipoproteins in the blood. This was indicative of stabilization of the pancreatic cell membrane systems.
Smirnov
D A
DA
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004359:Drug Therapy, Combination; D005260:Female; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000097:blood / Q000188:drug therapy*; D014494:Unithiol / Q000494:pharmacology / Q000627:therapeutic use*; D014810:Vitamin E / Q000494:pharmacology / Q000627:therapeutic use*
D005609:Free Radicals; D008077:Lipoproteins, LDL; D014810:Vitamin E; D014494:Unithiol
Ostryĭ pankreatit i bioantioksidanty.