[Current data on the screening of malignant hyperthermia during anesthesia].
A rare complication of general anesthesia, malignant hyperthermia is nonetheless very topical because it causes the death of young, healthy subjects who most often undergo surgery with no vital risk. Screening, an essential means of achieving riskless anesthesia, is based on testing on fresh biopsy specimens of muscle. The current state of knowledge, especially the progress made in genetics, will be commented.
Krivosic-Horber
R
R
Département d'Anesthésie réanimation chirurgicale, Centre Hospitalier Régional Universitaire, Lille.
Adnet
P
P
D000768:Anesthesia, General / Q000009:adverse effects* / Q000401:mortality; D002110:Caffeine / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism; D006221:Halothane / Q000494:pharmacology; D006801:Humans; D008305:Malignant Hyperthermia / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000378:metabolism* / Q000473:pathology; D011237:Predictive Value of Tests; D012307:Risk Factors
D002110:Caffeine; D002118:Calcium; D006221:Halothane
Actualités sur le dépistage de l'hyperthermie maligne anesthésique.