title: Prolonged intracoronary infusion of streptokinase: an alternative pharmacologic approach to extensive thrombus in native coronary artery.
abstract: Several reports suggest that pretreatment of intracoronary thrombus with fibrinolytic agents may reduce the risk for complications during subsequent balloon angioplasty. We report a case, for the first time, of successful lysis of an extensive thrombus in a native coronary artery by administering a prolonged intracoronary infusion of streptokinase to facilitate subsequent angioplasty and discuss the management strategy when intracoronary thrombus is encountered.
authors.affiliation: Beth Israel Medical Center, New York, New York 10003.
authors.forename: O
authors.initials: O
authors.lastname: Kjellgren
authors.forename: J R
authors.initials: JR
authors.lastname: Wilentz
authors.forename: L
authors.initials: L
authors.lastname: Kaganovsky
authors.forename: W
authors.initials: W
authors.lastname: Sherman
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003131:Combined Modality Therapy; D003328:Coronary Thrombosis / Q000188:drug therapy* / Q000628:therapy; D003331:Coronary Vessels; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D013300:Streptokinase / Q000008:administration & dosage / Q000627:therapeutic use*; D015912:Thrombolytic Therapy / Q000379:methods
chemical_list: D013300:Streptokinase