[Safety of azithromycin in patients allergic to penicillin and cephalosporin].
We have evaluated the safety of a new antibiotic, azithromicin, in 48 patients with allergy to penicillin and/or to cephalosporin. Diagnosis of allergy was based on clinical history, skin test and detection of serum specific IgE. The most common symptoms were urticaria, oedema, pruritus, oral aphthosis. Azithromicin was administered at the increasing dosage of 100-200-300 and 400 mg every 2 days. Our patients did not show any reaction to azithromicin. This antibiotic is therefore a valid alternative to penicillin and/or cephalosporin in patients allergic to these two drugs.
Pacor
M L
ML
Istituto di Clinica Medica Generale, Università degli Studi di Verona.
Biasi
D
D
Maleknia
T
T
Lunardi
C
C
D017963:Azithromycin / Q000008:administration & dosage / Q000276:immunology / Q000494:pharmacology*; D002511:Cephalosporins / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D010406:Penicillins / Q000276:immunology*; D012882:Skin Tests
D002511:Cephalosporins; D010406:Penicillins; D007073:Immunoglobulin E; D017963:Azithromycin
Sicurezza dell'azitromicina in pazienti allergici a penicillina e cefalosporina.