title: Less platelet damage in the curved vane centrifugal pump: a comparative study with the roller pump in open heart surgery.
abstract: The centrifugal pump with the curved vane (Lifestream Centrifugal Pump [LCP]) was applied to cardiopulmonary bypass (CPB) in 10 patients who underwent elective coronary artery bypass grafting. Serum hemoglobin levels, platelet counts, and serum beta-thromboglogulin (beta-TG) levels were measured during CPB. The results were compared with those for a comparative roller pump (RP) group (n = 10). There was no difference in CPB time between LCP (112 +/- 22 min) and RP (121 +/- 22 min) groups. Serum beta-TG levels (ng/ml) were lower in the LCP group than in the RP group (34 +/- 9 vs. 101 +/- 80, 5 min; 81 +/- 33 vs. 236 +/- 112, 30 min; 120 +/- 53 vs. 314 +/- 100, 60 min after initiation of CPB; p < 0.05). There were no significant differences in hemolysis and platelet depletion. The LCP showed excellent hemodynamic performance with less blood trauma in clinical application to open heart surgery.
authors.affiliation: Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College.
authors.forename: T
authors.initials: T
authors.lastname: Nishinaka
authors.forename: H
authors.initials: H
authors.lastname: Nishida
authors.forename: M
authors.initials: M
authors.lastname: Endo
authors.forename: H
authors.initials: H
authors.lastname: Koyanagi
mesh_terms: D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D004867:Equipment Design; D005260:Female; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D001620:beta-Thromboglobulin / Q000032:analysis
chemical_list: D006454:Hemoglobins; D001620:beta-Thromboglobulin