S-adenosyl-methionine may protect transplanted hepatocytes against the toxic effects of cytokines.
Vara
E
E
Department of Biochemistry (Facultad de Medicina), Universidad Complutense, Madrid, Spain.
Arias-Díaz
J
J
García
C
C
Villa
N
N
Simón
C
C
Ortiz
P
P
Balibrea
J L
JL
D000818:Animals; D002469:Cell Separation; D017690:Cell Transplantation / Q000502:physiology*; D002478:Cells, Cultured; D016207:Cytokines / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism; D007375:Interleukin-1 / Q000494:pharmacology; D007700:Kinetics; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008099:Liver / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D012436:S-Adenosylmethionine / Q000494:pharmacology*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
D016207:Cytokines; D007375:Interleukin-1; D010743:Phospholipids; D014409:Tumor Necrosis Factor-alpha; D008315:Malondialdehyde; D012436:S-Adenosylmethionine; D007770:L-Lactate Dehydrogenase; D005978:Glutathione