Expression and localization of gamma-aminobutyric acid A (GABAA) receptor alpha 1 subunit and L-glutamate decarboxylase (GAD) mRNAs in rat retina: an analysis by in situ hybridization.
The localization of the mRNAs encoding gamma-aminobutyric acidA receptor alpha 1 subunit (GABAA alpha 1) and L-glutamate decarboxylase (GAD) was elucidated in the rat retina by in situ hybridization. Soma diameter analysis of signal positive cells in the ganglion cell layer demonstrated that a subpopulation including alpha-cells of retinal ganglion cells expressed GABAA alpha 1 mRNA and a subpopulation of ganglion cells smaller than alpha-cells expressed GAD mRNA.
Kosaka
J
J
Department of Physiology, Osaka University Medical School, Japan.
Morii
E
E
Taniguchi
M
M
Kitamura
Y
Y
Nomura
S
S
Fukuda
Y
Y
D000818:Animals; D005968:Glutamate Decarboxylase / Q000235:genetics*; D017403:In Situ Hybridization; D008297:Male; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis*; D051381:Rats; D017208:Rats, Wistar; D011963:Receptors, GABA-A / Q000235:genetics*; D012160:Retina / Q000737:chemistry* / Q000166:cytology; D012165:Retinal Ganglion Cells / Q000737:chemistry
D012333:RNA, Messenger; D011963:Receptors, GABA-A; D005968:Glutamate Decarboxylase