Low predictive value of an elevated prothrombin time for bleeding on oral anticoagulation.
This study is a retrospective analysis of 39 consecutive patients who had a prothrombin time of over 25 seconds with respect to the bleeding complications. This study finds that the overall risk of bleeding is low, 2/39 (5.1%), that there is no statistical difference in the values of the patients who bled when compared to those who did not, and that patients who bled tended to have a clearly identifiable precipitating event.
Shen
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EN
University of Hawaii, Department of Cardiology, Honolulu 96813.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006470:Hemorrhage / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011517:Prothrombin Time; D012189:Retrospective Studies; D014859:Warfarin / Q000009:adverse effects
D000925:Anticoagulants; D014859:Warfarin