[Influence of steroidal and nonsteroidal anti-inflammatory drugs on post-operative blood-aqueous barrier in pseudophakia].
Fluorophotometric evaluation of the tightness of blood-aqueous barrier was made in 2 groups of patients who underwent cataract surgery with IOLs implantation. The first group was treated with nonsteroidal (Naclof, Tolectin) and the second with steroidal (Dexamethasone, Hydrocortisone) anti-inflammatory drugs. Fluorophotometry of the anterior segment of the eye was performed for the quantitative examination of the inflammatory reaction. The leakage of fluorescein through the blood-aqueous barrier was evaluated and compared with the fellow, non-operated eye. The individual leakage coefficient, calculated according to Sanders, was lower in the group of patients treated with nonsteroidal drugs but the differences were not statistically significant. The results suggest that nonsteroidal drugs could be as efficient or even more efficient in the treatment of inflammatory reaction after cataract surgery with IOLs implantation.
Szymański
A
A
I Katedry i Kliniki Okulistyki Slaskiej AM, Katowice.
Gierek-Lapińska
A
A
Koziak
M
M
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001813:Blood-Retinal Barrier / Q000187:drug effects*; D002387:Cataract Extraction / Q000009:adverse effects*; D003907:Dexamethasone / Q000627:therapeutic use; D004008:Diclofenac / Q000627:therapeutic use; D009877:Endophthalmitis / Q000209:etiology / Q000517:prevention & control*; D015590:Fluorophotometry; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008875:Middle Aged; D014046:Tolmetin / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac; D003907:Dexamethasone; D014046:Tolmetin; D006854:Hydrocortisone
Wpływ sterydowych i niesterydowych leków przeciwzapalnych na pooperacyjna bariere krew-ciecz wodnista w pseudofakii.