title: [Effect of tuberculin on the clinical course and healing processes in experimental tuberculosis].
abstract: Two procedures for treating experimental tuberculosis were compared. One comprised a rapid administration of tuberculin up to large doses (20,000 TE), the other included weakly stimulating therapy with tuberculin (its maximum dose being 150 TE). Treatment with tuberculin in combination with isoniazid ensures a higher resolution of specific abnormalities than that with isoniazid alone. However, when either procedures were used, the weakly stimulating procedure led to experimental animals' death, which generates the need to take a preliminary account of the body's response to tuberculin in the clinical setting in order to choose tuberculin therapy on an individual basis.
authors.forename: V A
authors.initials: VA
authors.lastname: Krylov
authors.forename: V F
authors.initials: VF
authors.lastname: Titov
authors.forename: V S
authors.initials: VS
authors.lastname: Tereshin
mesh_terms: D000818:Animals; D004359:Drug Therapy, Combination; D006168:Guinea Pigs; D007279:Injections, Subcutaneous; D007538:Isoniazid / Q000627:therapeutic use*; D008954:Models, Biological; D013997:Time Factors; D016896:Treatment Outcome; D014373:Tuberculin / Q000627:therapeutic use*; D014376:Tuberculosis / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D014373:Tuberculin; D007538:Isoniazid
vernacular_title: Vliianie tuberkulina na techenie i protsessy zazhivleniia éksperimentalńogo tuberkulëza.