Paradoxical poor prognosis of myeloma patients who demonstrate complete healing of bone lesions following treatment.
Multiple myeloma is the most common primary malignant bone neoplasm in adults, primarily over the age of 40. The most common radiographic findings include osteopenia, lytic lesions, and pathologic fractures. Although marked bone repair and healing can occur following therapy, this is often, paradoxically, a poor prognostic indicator.
Wulfeck
D W
DW
Department of Diagnostic Radiology, Humana Hospital University of Louisville, KY 40202.
Williams
T E
TE
D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D010384:Pelvic Bones / Q000000981:diagnostic imaging; D011379:Prognosis; D011859:Radiography