[Fitness by cold stimulation of various intensity: effects on metabolism of purines and free radicals].
Whole-body cold stimuli lead to a dosage-depended decrease of uric acid level in blood plasma. This could be observed in own studies on winter-swimming and cold shower application and in studies on patients treated by cold-chamber-therapy. This uric acid decrease is due to an accelerated oxygen radical formation during cold exposition rather than to an inhibition of purine metabolism. The acute oxidative loading due to cold exposure and the long-term antioxidative adaptation may be interpreted as a new molecular mechanism resulting in body hardening.
Brenke
R
R
Klinik und Poliklinik für Physikalische Medizin und Rehabilitation, Berlin, Deutschland.
Siems
W
W
Maass
R
R
D000293:Adolescent; D000328:Adult; D017679:Cryotherapy / Q000379:methods*; D005260:Female; D005609:Free Radicals; D006801:Humans; D008297:Male; D008875:Middle Aged; D010809:Physical Fitness / Q000502:physiology*; D011687:Purines / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D014527:Uric Acid / Q000097:blood
D005609:Free Radicals; D011687:Purines; D017382:Reactive Oxygen Species; D014527:Uric Acid
Abhärtung durch Kaltreize unterschiedlicher Intensität: Wirkungen auf den Purin- und Radikalmetabolismus.