Current status of interventional neuroradiology in the management of meningiomas.
Most meningiomas are benign and therefore curable lesions. Currently, the best available treatment is complete surgical resection. Toward this end, interventional neuroradiologists should contribute to the efficient and total removal of tumor mass. Although some controversy exists as to the value of the embolization of meningiomas involving the convexity, preoperative embolization certainly is of value in more complex presentations, including giant meningiomas, meningiomas exhibiting malignant or angioblastic characteristics, as well as those involving the skull base, scalp, or critical vascular structures. Several reports have illustrated the importance of preoperative embolization in reducing blood supply to lesions in surgically inaccessible areas. Moreover, several arguments may be advanced in defense of embolization as a method of devascularization superior to dural vessel ligation at the time of operation. Microemboli enter the vascular bed of the tumor and devascularize the lesion irrespective of collateral circulation. In addition, bilateral dural devascularization is easier to accomplish via endovascular techniques and may obviate the need for surgical exposure of the contralateral side during resections of tumors involving the falx or parasagittal region. The tumor necrosis occurring after devascularization by microparticulate emboli may facilitate surgical manipulation. At a theoretical level, embolization may reduce the likelihood of recurrence, particularly from unnoticed invasion of dural venous sinuses or from the surrounding dura. To achieve these goals, embolization should be as complete as possible. This requires a thorough understanding of the disease process and the vascular anatomy involved and superb technique.
New York University School of Medicine and Medical Center, New York.
P K
PK
Nelson
A
A
Setton
I S
IS
Choi
J
J
Ransohoff
A
A
Berenstein
D002533:Cerebral Angiography; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D008577:Meningeal Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D008579:Meningioma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D011300:Preoperative Care; D015641:Radiography, Interventional / Q000379:methods*; D015996:Survival Rate