Neurochemical gradient along the monkey occipito-temporal cortical pathway.
We have examined the neuronal distribution of two calcium-binding proteins, calbindin (CB) and parvalbumin (PV), along the occipito-temporal cortical pathway, which sequentially connects visual areas V1, V2, V4, TEO, and TE, and then areas TG and 36 in monkeys. Immunohistochemical staining showed that CB-containing pyramidal cells, which were mostly limited to layers 2 and 3, gradually increased in population from the posterior to the anterior areas. PV-containing non-pyramidal cells were sparser in areas TG and 36 than in the other areas. The posterior and anterior areas of the occipito-temporal cortical pathway are different in the chemical characteristics of their neurones.
Laboratory for Neural Information Processing, Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.
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H
Kondo
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T
Hashikawa
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K
Tanaka
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EG
Jones
D000818:Animals; D064026:Calbindins; D008251:Macaca; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009778:Occipital Lobe / Q000737:chemistry*; D010320:Parvalbumins / Q000032:analysis*; D017966:Pyramidal Cells / Q000737:chemistry; D064030:S100 Calcium Binding Protein G / Q000032:analysis*; D013702:Temporal Lobe / Q000737:chemistry*; D014795:Visual Pathways / Q000737:chemistry*
D064026:Calbindins; D009419:Nerve Tissue Proteins; D010320:Parvalbumins; D064030:S100 Calcium Binding Protein G