Scintigraphic manifestations of "sternal cupping".
Sternal abnormalities in sickle-cell disease have been documented by bone scintigraphy and radiography in patients with homozygous sickle-cell anemia, but not in patients with sickle-thalassemia. We present here two unusual cases of sternal abnormalities in complicated sickle-cell disease. One is an infant with radiographic findings of "sternal cupping" and transient hypo-ossification of the sternum and sickle-thalassemia. The other patient is also a male infant with unusual, persistent under-ossification of bone, in association with radiographic findings of "sternal cupping." The second patient also had a 4P-chromosomal defect (Wolf-Hirschhorn syndrome) in which sternal hypo-ossification was described.
Barron
B J
BJ
Department of Radiology, University of Texas Health Science Center at Houston.
Robinson
L
L
Tran
H D
HD
Lamki
L
L
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging; D000755:Anemia, Sickle Cell / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008297:Male; D011877:Radionuclide Imaging; D013249:Sternum / Q000000981:diagnostic imaging*; D013577:Syndrome; D013789:Thalassemia / Q000000981:diagnostic imaging