[Gougerot-Sjögren syndrome. Central neurological involvement with recurrent development].
A 64-year-old woman was repeatedly hospitalized for various recurrent clinical signs of central nervous system involvement. The diagnosis of primary Sjögren's syndrome was established 3 years 6 months after the onset of the disease. Sicca symptoms, as well as inflammatory biological abnormalities were absent. Moreover, both lacrymal and salivary gland secretions were affected. A high level of antinuclear antibodies to SSA and SSB was associated with inflammatory lesions in minor salivary glands biopsy samples consistent with the diagnosis of Sjögren's syndrome.
Ménage
P
P
Clinique Neurologique, Hôpital Bretonneau, Tours.
de Toffol
B
B
Degenne
D
D
Saudeau
D
D
Bardos
P
P
Autret
A
A
D000974:Antibodies, Antinuclear / Q000032:analysis; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012008:Recurrence; D012859:Sjogren's Syndrome / Q000150:complications*
D000974:Antibodies, Antinuclear
Syndrome de Gougerot-Sjögren primitif. Atteinte neurologique centrale évoluant par poussées.