The effect of removing the true dental follicle on premolar eruption in the dog.
Eruption is a highly localized process during which the bone resorption and formation that occur on opposite sides of the tooth are dependent upon the surrounding soft tissues, the true dental follicle externally and the enamel organ internally. To examine the ability of the enamel organ to cause eruption the external layer (dental follicle) was removed just prior to and up to 4 weeks before eruption in 13 mandibular premolars in dogs and eruption followed clinically, radiographically and histologically. None of the teeth without dental follicles erupted but three teeth from which the follicle was separated then replaced did erupt. These data indicate that the enamel organ without the dental follicle cannot support tooth eruption and provide indirect evidence for the central role of the dental follicle, alone or in combination with the enamel organ, in eruption.
Department of Cell Biology, University of Massachusetts Medical Center, Worcester 01655.
E K
EK
Larson
D R
DR
Cahill
J P
JP
Gorski
S C
SC
Marks
D000818:Animals; D001641:Bicuspid / Q000033:anatomy & histology / Q000502:physiology*; D003743:Dental Enamel / Q000033:anatomy & histology / Q000502:physiology; D003795:Dental Sac / Q000502:physiology* / Q000601:surgery; D004285:Dogs; D008334:Mandible; D014078:Tooth Eruption / Q000502:physiology*