[Structural glycoproteins and integrins].
Structural glycoproteins are multifunctional proteins which play a dual role in extracellular matrix: they contribute to the supramolecular organization of extracellular matrices and participate in cell-matrix interactions. Some of their receptors, the integrins, are not only adhesion molecules but there is increasing evidence that they may transduce signals from outside-in the cells and from inside-out the cells although all the mechanisms of this "transducing" activity are still not completely understood.
Laboratoire de Biologie du Tissu conjonctif, URA CNRS 1460, Faculté de Médecine, Université Paris XII.
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Labat-Robert
D000818:Animals; D016326:Extracellular Matrix Proteins; D006023:Glycoproteins; D016023:Integrins / Q000145:classification / Q000378:metabolism / Q000648:ultrastructure
D016326:Extracellular Matrix Proteins; D006023:Glycoproteins; D016023:Integrins
Glycoprotéines de structure et intégrines.