Patient with unusual alternating hemiplegia.
A patient with unusual alternating hemiplegia in childhood is reported. The frequency of hemiplegic episodes was lower than that in other reported patients. Interictal positron emission tomography revealed decreased cerebral blood flow in the left hemisphere. After cerebral angiography, postanesthetic irritability occurred which evolved into coma with hemiplegic episodes. We believe that cerebral angiography in a child with alternating hemiplegia may cause hemiplegic episodes and coma. The episodes disappeared almost completely for 6 years after treatment with flunarizine, thus indicating the benefit of the medication for the treatment of alternating hemiplegia.
Department of Pediatrics, Kyoto Prefectural University of Medicine, Japan.
T
T
Nishiki
Y
Y
Takeuchi
I
I
Yamazoe
H
H
Yoshioka
T
T
Sawada
D001479:Basal Ganglia / Q000098:blood supply / Q000503:physiopathology; D002533:Cerebral Angiography; D002540:Cerebral Cortex / Q000098:blood supply / Q000503:physiopathology; D002648:Child; D003128:Coma / Q000188:drug therapy / Q000503:physiopathology*; D004292:Dominance, Cerebral / Q000187:drug effects / Q000502:physiology*; D004569:Electroencephalography / Q000187:drug effects; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D005444:Flunarizine / Q000627:therapeutic use; D005500:Follow-Up Studies; D006429:Hemiplegia / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D002546:Ischemic Attack, Transient / Q000188:drug therapy / Q000503:physiopathology; D012008:Recurrence; D012039:Regional Blood Flow / Q000187:drug effects / Q000502:physiology; D013226:Status Epilepticus / Q000188:drug therapy / Q000503:physiopathology; D014055:Tomography, Emission-Computed
D005444:Flunarizine