Superinfection exclusion by T-even-type coliphages.
When a bacterial cell is infected with a T-even coliphage, immunity to a superinfecting phage is rapidly established (superinfection exclusion). Two phage-encoded proteins, Imm and Sp, are responsible for this exclusion: Imm blocks DNA transfer across the plasma membrane and partially inhibits release of DNA from the superinfecting virion, and Sp inhibits local degradation of bacterial murein by a phage-associated lysozyme.
Lu
M J
MJ
Universitätsklinikum Essen, Institut für Virologie, Germany.
Henning
U
U
D000595:Amino Acid Sequence; D008969:Molecular Sequence Data; D013604:T-Phages / Q000235:genetics / Q000502:physiology*; D014779:Virus Replication