[Effect of glycosylation on collagen type I fibrillogenesis in a model of connective tissue].
Glycated collagen could be used to prepare fibroblast populated collagen lattice. But with glycated collagen, the retraction kinetics of this tissue equivalent were slower than those with control collagen. The ultrastructural study showed a decrease of the fiber density. So the glycation decreased the collagen type I fibrillogenesis.
Laboratoire de Biochimie, Faculté de Médecine, Saint-Etienne.
J
J
Frey
C
C
Perier
N
N
Raby
A
A
Chamson
D003094:Collagen / Q000378:metabolism*; D003238:Connective Tissue / Q000378:metabolism; D005347:Fibroblasts / Q000378:metabolism; D006031:Glycosylation; D006801:Humans; D008854:Microscopy, Electron
D003094:Collagen
Effets de la glycation sur la fibrillogenèse du collagène de type I dans un modèle de tissu conjonctif.