Arterial or mixed venous lactate measurement in critically ill children. Is there a difference?
Seven critically ill children had simultaneous measurement of whole blood lactate concentrations obtained from a systemic arterial and mixed venous (pulmonary artery) site. An excellent correlation was found (r = 0.995). The mean difference between arterial and mixed venous values was 0.02 mmol/l and the limits of agreement (+/- 0.22) were -0.20 to 0.24. The differences found were clinically insignificant (two-tailed paired Student's t-test; p = 0.36) and therefore support the continued use of arterial sampling for blood lactate measurement.
Department of Paediatric Cardiology, Guy's Hospital, London, UK.
I A
IA
Murdoch
C
C
Turner
R N
RN
Dalton
D001158:Arteries; D002648:Child; D002675:Child, Preschool; D016638:Critical Illness; D006801:Humans; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D014680:Veins
D007773:Lactates; D019344:Lactic Acid