Endodermal sinus tumor: report of 12 cases.
Twelve cases of endodermal sinus tumor were reviewed. There were 10 females and 2 males with a median age at presentation of 3 years. The primary site was sacrococcygeal in 4 patients, vaginal in 3, retroperitoneal in 2, and testicular, ovarian and left chest wall in one each. The diagnosis rested on histopathological examination and elevation of serum alfa feto protein levels (median 46,200 ng/ml). Two patients had Stage I disease, 9 had Stage III and one had Stage IV disease. Patients were managed by surgery and chemotherapy (BVP regime). All patients on BVP (even those lost at later stages), had achieved clinical remission with the first cycle of treatment.
Department of Pediatric Hematology and Oncology, B.J. Wadia Hospital for Children, Parel, Bombay.
B R
BR
Agarwal
M
M
Patel
B N
BN
Shah
Z
Z
Currimbhoy
V S
VS
Waingankar
I
I
Meisheri
V K
VK
Kapur
A K
AK
Murthy
D002648:Child; D002675:Child, Preschool; D018240:Endodermal Sinus Tumor; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010051:Ovarian Neoplasms; D012186:Retroperitoneal Neoplasms; D012445:Sacrococcygeal Region; D013736:Testicular Neoplasms; D013899:Thoracic Neoplasms; D014625:Vaginal Neoplasms