[Injection of 5-fluorouracil in the treatment of tubal pregnancy through salpingo-catheter under hysteroscopy].
Seventeen women with unruptured tubal pregnancy were given 5-FU through salpingo-catheter under hysteroscopy. In one case the injection failed because the tube opening could not be found. The success rate of salpingo-catheterization was 94.12% (16/17). The cure rate for the tubal pregnancies was 88.24% (15/17). 12 cases received injection once and 3 cases twice. The dose of 5-FU per injection was 250 mg in 10 ml solution. Serum beta-hCG test became negative in 7 to 14 days after the treatment, and signs and symptoms disappeared. Salpingography were done in 8 cases after 2 to 3 months, and all the diseased tubes were found patient. There was little side effects due to this treatment, which is more effective, convenient and less traumatic than injecting 5-FU to the affected site through laparoscopy or systemic administration. It may turn out to be an effective, simple, safe and acceptable new method for treating early tubal pregnancy.
Women and Children's Hospital of Foshan, Guangdong.
Q H
QH
Xie
X C
XC
Liu
S Y
SY
Liu
D000328:Adult; D002404:Catheterization; D005187:Fallopian Tubes; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D015907:Hysteroscopy; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000188:drug therapy*
D005472:Fluorouracil