Endometrial receptivity in the light of modern assisted reproductive technologies.
OBJECTIVE
To review the different aspects of endometrial receptivity as it is reflected in the various modalities of modern assisted reproductive technologies.


METHODS
The importance of endometrial receptivity and the factors that affect it such as the type of treatment, age, and ovarian function are discussed in this review. Novel approaches to determine receptivity such as Doppler ultrasonography and molecular biology are considered; assisted hatching is also discussed.


CONCLUSIONS
Endometrial receptivity cannot, as yet, be directly assessed. Circumstantial evidence suggests that receptivity declines with age, is adversely affected by controlled ovarian hyperstimulation, and is possibly affected by ovarian function. Future studies will have to focus on molecular cell biology and physiology of the endometrium.
Vitro Fertilization/Embryo Transfer Unit, Serlin Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.
Y
Y
Yaron
A
A
Botchan
A
A
Amit
M R
MR
Peyser
M P
MP
David
J B
JB
Lessing
D000375:Aging / Q000502:physiology; D004624:Embryo Transfer; D005314:Embryonic and Fetal Development; D004717:Endometrium / Q000502:physiology*; D005260:Female; D005298:Fertility; D005307:Fertilization in Vitro; D006728:Hormones / Q000502:physiology; D006801:Humans; D009865:Oocytes; D012099:Reproductive Techniques / Q000639:trends*; D014019:Tissue Donors; D014463:Ultrasonography
D006728:Hormones