The "count loss" artifact in Tc-99m HMPAO leukocyte SPECT of the abdomen.
During SPECT studies of the abdomen with Tc-99m labeled autologous leukocytes, the authors had observed false defects involving the vertebral bodies of the lower thoracic spine in two patients. To investigate this "count loss" artifact, a phantom simulating liver, spleen, and spine was constructed. Four clinical situations were simulated by positioning cylinders in the different locations: normal spine-spleen model, normal liver-spine-spleen model, spine-enlarged spleen model, and enlarged liver-spine-enlarged spleen model. SPECT studies were performed at different concentration ratios between the spleen and the spine on the disparate models with varying distance from the spleen to the spine. The results showed that the count loss artifact is not only related to the concentration ratio between the structures but also is related to the size, position, and distance between the structures. The correction steps for this artifact include: 1) identifying average count value of the spine and spleen from ECT sinogram count data, and 2) replacing the original high-count value in the spleen by the count value close to the average value at the region of the spine in the 120 raw projection data. Using these new modified ECT data, the reconstructed orthogonal images are almost free of the count loss artifact.
Department of Radiation Oncology & Nuclear Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107.
J J
JJ
Zhang
S M
SM
Kim
C H
CH
Park
C M
CM
Intenzo
D000005:Abdomen / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D016477:Artifacts; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007962:Leukocytes; D008099:Liver / Q000000981:diagnostic imaging; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D008297:Male; D008961:Models, Structural; D015609:Organotechnetium Compounds; D010091:Oximes; D013154:Spleen / Q000000981:diagnostic imaging*; D019690:Technetium Tc 99m Exametazime; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime