The differential pattern of memory deficit in normal aging and dementias of different etiology.
The study explored encoding, storage, and retrieval components of memory functioning in four groups of subjects: (1) normal elderly; (2) elderly subjects in the early prestages of DAT; (3) elderly subjects with a more advanced DAT; (4) younger subjects in the early prestages of AIDS dementia. Each group consisted of 26 subjects, who were administered the Rey Auditory-Verbal Learning Test. The results suggest impaired encoding and retrieval in the DAT groups. The AIDS group demonstrated deficient storage and retrieval. Their pattern of memory deficits was similar to that seen in normal aging. The results speak in favor of the hypothesis of subcortical nature of neurological changes in normal aging.
UCLA School of Medicine, California State University, Northridge Olive View/UCLA Medical Center.
M
M
Mitrushina
P
P
Satz
C
C
Drebing
W
W
Van Gorp
A
A
Mathews
J
J
Harker
A
A
Chervinsky
D015526:AIDS Dementia Complex / Q000175:diagnosis / Q000209:etiology / Q000523:psychology; D000328:Adult; D000367:Age Factors; D000368:Aged; D000647:Amnesia / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology; D001288:Attention; D003704:Dementia / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011594:Psychometrics; D012016:Reference Values; D012153:Retention, Psychology