Studies on the embryotoxic and teratogenic effects of Tołpa Peat Preparation.
Neither embryotoxic nor teratogenic effects were observed in hamsters and rats after administration of Tołpa Peat Preparation (TPP) in doses of 5 and 50 mg/kg daily. Some maternal toxicity in rats and some embryotoxic effect in hamsters were recorded after the highest dose of TPP (250 mg/kg daily).
Department of Pharmacology and Toxicology, National Veterinary Research Institute, Puławy, Poland.
T
T
Juszkiewicz
M
M
Minta
B
B
Włodarczyk
B
B
Biernacki
J
J
Zmudzki
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000596:Amino Acids / Q000633:toxicity*; D000818:Animals; D002241:Carbohydrates / Q000633:toxicity*; D006224:Cricetinae; D004338:Drug Combinations; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D005260:Female; D006812:Humic Substances / Q000633:toxicity*; D011247:Pregnancy; D051381:Rats; D012987:Soil; D013723:Teratogens / Q000633:toxicity*; D014574:Uronic Acids / Q000633:toxicity*
D000596:Amino Acids; D002241:Carbohydrates; D004338:Drug Combinations; D006812:Humic Substances; D012987:Soil; D013723:Teratogens; C084029:Tolpa; D014574:Uronic Acids