Neutrophil function and dysfunction in periodontal disease.
The polymorphonuclear leukocyte or neutrophil is an integral part of the acute inflammatory response. Its function as a protective cell in the pathogenesis of periodontal disease has been studied extensively. Abnormal neutrophil function has been associated (directly or indirectly) with the pathogenesis of early onset periodontal disease. This paper reviews the recent developments in neutrophil function and dysfunction as they relate to periodontal disease progression.
Van Dyke
T E
TE
Eastman Dental Center, Rochester, New York.
Vaikuntam
J
J
D003602:Cytotoxicity, Immunologic; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006801:Humans; D006997:Hypochlorous Acid / Q000378:metabolism; D009504:Neutrophils / Q000276:immunology* / Q000378:metabolism; D010510:Periodontal Diseases / Q000276:immunology* / Q000378:metabolism / Q000382:microbiology; D017382:Reactive Oxygen Species / Q000378:metabolism; D016897:Respiratory Burst; D013481:Superoxides / Q000378:metabolism
D017382:Reactive Oxygen Species; D013481:Superoxides; D006997:Hypochlorous Acid