Localization of the glucagon receptor gene to human chromosome band 17q25.
The gene encoding the human glucagon receptor (GCGR) was mapped to chromosome band 17q25 by fluorescence in situ hybridization to metaphase chromosomes. An Alu variable poly(A) DNA polymorphism was identified in this gene. Studies in the CEPH families showed significant evidence of linkage between DNA polymorphism and markers localized to the distal long arm of chromosome 17.
Howard Hughes Medical Institute, University of Chicago, Illinois 60637.
S
S
Menzel
M
M
Stoffel
R
R
Espinosa
A A
AA
Fernald
M M
MM
Le Beau
G I
GI
Bell
D001483:Base Sequence; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D004247:DNA; D005819:Genetic Markers; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D018027:Receptors, Glucagon / Q000235:genetics*
D005819:Genetic Markers; D018027:Receptors, Glucagon; D004247:DNA