Immune response of the elderly to rabies vaccines.
A serological study has been performed to detect the antibody response to full schedules of two anti-rabies vaccines (PDEV and HDCV). Subjects aged > 50 years, compared with subjects 11-25 years, showed significantly lower titres after the 4th dose (and, to a lesser extent, after the 5th dose), suggesting that, among the elderly, the 6th dose is strongly desirable.
Department of Experimental Biology, University of Cagliari, Italy.
I
I
Mastroeni
N
N
Vescia
M G
MG
Pompa
M S
MS
Cattaruzza
G P
GP
Marini
G M
GM
Fara
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D006801:Humans; D008875:Middle Aged; D011819:Rabies Vaccines / Q000276:immunology*; D011820:Rabies virus / Q000276:immunology*
D000914:Antibodies, Viral; D011819:Rabies Vaccines