Reflex sympathetic dystrophy syndrome.
There has been increasing interest in reflex sympathetic dystrophy syndrome (RSDS) over the past decade. This trend has continued over the past 2 years with the publication of a number of reports and studies, many of which are reviewed here. Progress has been made in understanding RSDS, with the demonstration of increased alpha-adrenergic receptor activity in peripheral nerves following injury. Release of alpha-adrenergic agonists from sympathetic nerve terminals may then cause nociceptor activation and pain. Use of phentolamine, an alpha-adrenergic receptor inhibitor, in a diagnostic test may provide a more specific method for recognizing RSDS.
Kozin
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D006801:Humans; D012019:Reflex Sympathetic Dystrophy / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D013577:Syndrome