Alginate fiber dressing for oral mucosal wounds.
The aim of this study was to evaluate the effect on hemostasis and wound healing of a proprietary alginate fiber dressing when applied to a wound of the buccal mucosa of approximately 2 mm depth. The study showed a significant reduction in the number of residual bleeding points in shallow wounds when the alginate fiber dressing was applied for 5 minutes as compared with the use of non-alginate-impregnated surgical gauze. There was no significant difference in the rate of epithelial repair of the test and control sites nor in the area of the resulting mucosal scar. In addition, there was no significant difference in the numbers of tissue components in the submucosa. It is concluded that the alginate fiber dressing material evaluated in this study may be effective as a hemostatic mucosal dressing in shallow wounds, but it does not accelerate mucosal wound healing.
Matthew
I R
IR
University of Birmingham, School of Dentistry.
Browne
R M
RM
Frame
J W
JW
Millar
B G
BG
D000464:Alginates / Q000627:therapeutic use*; D000818:Animals; D004285:Dogs; D020723:Glucuronic Acid; D006490:Hemostatics / Q000627:therapeutic use*; D006603:Hexuronic Acids; D009061:Mouth Mucosa / Q000293:injuries*; D009779:Occlusive Dressings; D014945:Wound Healing
D000464:Alginates; D006490:Hemostatics; D006603:Hexuronic Acids; D020723:Glucuronic Acid