[Long-term sensitization in the snail: the electrophysiological correlates in the command neurons of defensive behavior].
The long-term sensitization of defensive reflex led to an increase of excitability of the command neurons LPa3 and RPa3, controlling the defensive pneumostome contraction reaction due to a depolarization shift of the membrane potential and a decrease of the threshold potential. Depletion of dopamine by amphetamine injection also led to an increase of excitability in these command neurons mainly due to a decrease of the threshold potential. Sensitization of animals after amphetamine treatment resulted in a partial summation of effects--a reliable decrease of the threshold potential in comparison with the sensitized snails and amphetamine-treated ones. It was concluded that the increases of excitability during the long-term sensitization and amphetamine treatment were underlain by different mechanisms.
Kh L
KhL
Gaĭnutdinov
N A
NA
Beregovoĭ
D000200:Action Potentials / Q000187:drug effects / Q000502:physiology; D000818:Animals; D003913:Dextroamphetamine / Q000494:pharmacology; D004924:Escape Reaction / Q000187:drug effects / Q000502:physiology*; D006372:Helix, Snails / Q000187:drug effects / Q000502:physiology*; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D010812:Physical Stimulation / Q000379:methods; D012621:Seasons; D013997:Time Factors
D003913:Dextroamphetamine
Dolgovremennaia sensitizatsiia u vinogradnoĭ ulitki: élektrofiziologicheskie korreliaty v komandnykh neĭronakh oboronitel'nogo povedeniia.