[Effects of the combination of Astragalus membranaceus (Fisch.) Bge. (AM), Angelica sinensis (Oliv.) Diels (TAS), Cyperus rotundus L. (CR), Ligusticum chuangxiong Hort (LC) and Peaonìa veitchii lynch (PV) on the hemorheological changes in "blood stagnating" rats].
The "blood stagnating" rat model was built with adrenaline and cold stimulation. Its hemorrheological character was an increase in the viscosity, thickness and liability to coagulate. The experimental result showed that AM and TAS could decrease the whole blood specific viscosity, but at the same time increase the plasma specific viscosity. The qi-regulating drug CR and two blood-activating drugs LC and PV could improve the hemorrheological changes in "blood stagnating" rats. The combination of qi-regulating drugs and blood-activating drugs had more favorable effect.
Institute of Traditional Chinese Materia Medica, China Pharmaceutical University, Nanjing.
J X
JX
Xue
Y Q
YQ
Yan
Y
Y
Jiang
D000818:Animals; D027885:Astragalus propinquus; D001809:Blood Viscosity / Q000187:drug effects*; D003080:Cold Temperature; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004903:Erythrocyte Aggregation / Q000187:drug effects; D006400:Hematocrit; D018056:Hemorheology / Q000187:drug effects*; D030004:Ligusticum; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley
D004365:Drugs, Chinese Herbal; C101574:chuangxiong extract