Chemolysis of calcium containing urinary calculi. A review.
A review of current literature and research on chemolysis of calcium containing urinary stones is made. The type of chemolytic solution is dependent upon the composition of the stone. Calcium phosphates can be desolved with Suby or Renadecin solution although it is often tedious and time consuming procedure. Calcium oxalate, the major urinary stone component, can not be dissolved by these solutions. EDTA and other strong calcium chelators cannot be used because of their local toxicity. Certain enzymes can digest the organic matrix of the stone. The indication to chemolysis of stones are rather restricted.
Department of Urology, University of Ghent.
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Oosterlinck
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Verbeeck
D002118:Calcium / Q000378:metabolism*; D002129:Calcium Oxalate / Q000378:metabolism; D002951:Citrates / Q000009:adverse effects / Q000627:therapeutic use; D004492:Edetic Acid / Q000627:therapeutic use; D006801:Humans; D007669:Kidney Calculi / Q000188:drug therapy; D014545:Urinary Calculi / Q000188:drug therapy* / Q000378:metabolism
D002951:Citrates; C026485:hemiacidrin; D002129:Calcium Oxalate; D004492:Edetic Acid; D002118:Calcium