Glucosidase inhibition assay as prescreen for natural products.
A glucosidase inhibition assay has been used to evaluate extracts from higher plants. An enzyme inhibition of fifty percent or more correlated with the observed cytotoxicity of the extracts.
Antoun
M D
MD
Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico, San Juan 00936-5067.
Ríos
Y R
YR
Mendoza
N T
NT
Proctor
G
G
D000998:Antiviral Agents / Q000494:pharmacology; D016923:Cell Death / Q000187:drug effects; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D006678:HIV / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology* / Q000633:toxicity; D011647:Puerto Rico; D001617:beta-Glucosidase / Q000037:antagonists & inhibitors*
D000998:Antiviral Agents; D010936:Plant Extracts; D001617:beta-Glucosidase