[Synthesis of certain derivatives of methoxy-5-[(benzazole-2-yl)thioacetylamino]-3-dihydro-2,3-benzofuran and research on their antihypertensive activity].
In this study, some 5-methoxy-3-[benzazole-2-yl)thioacetylamino]-2,3-dihydrobenzofuran derivatives were synthesized and their structures were elucidated by IR, NMR and microanalyses. The antihypertensive activities of the compounds obtained were investigated.
Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Université d'Anadolu, Eskişehir, Türkiye.
G
G
Turan-Zitouni
S
S
Demirayak
K
K
Erol
M
M
Ozdemir
D000818:Animals; D000959:Antihypertensive Agents / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D001572:Benzofurans / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005260:Female; D066298:In Vitro Techniques; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D009638:Norepinephrine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D011817:Rabbits
D000959:Antihypertensive Agents; D001572:Benzofurans; D009638:Norepinephrine
Synthèse de certains derivès de methoxy-5 [(benzazole-2-yl) thioacetylamino]-3 dihydro-2,3 benzofurane et recherche d'activité antihypertensive.