Effect of theophylline on periodic breathing in congestive heart failure measured by transcutaneous oxygen monitoring.
The effect of theophylline on periodic breathing was measured by transcutaneous oxygen monitoring in 7 patients suffering from chronic congestive heart failure. Theophylline significantly decreased the frequency of Cheyne-Stokes breathing. Transcutaneous oxygen monitoring proved to be a useful method to follow changes in the breathing pattern. The suggested mechanism of action of theophylline in reducing the incidence of periodic breathing is blockade of adenosine receptors.
National Korányi Institute for Tuberculosis and Pulmonology, Budapest, Hungary.
J
J
Tomcsányi
K
K
Karlócai
D000328:Adult; D000368:Aged; D001785:Blood Gas Monitoring, Transcutaneous; D002908:Chronic Disease; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012119:Respiration / Q000187:drug effects*; D013806:Theophylline / Q000494:pharmacology*
D013806:Theophylline