Structure and possible function of an alpha-tocopherol-binding protein.
A protein has been isolated from rat liver cytosol that specifically binds alpha-tocopherol. It does not occur in other tissues. Its amino acid sequence has been determined and it was found to have great homology with 11-cis-retinaldehyde-binding protein of the retina. This tocopherol-binding protein may be defective in a certain type of familial vitamin E deficiency syndrome.
University of California, Berkeley.
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Wolf
D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology*; D006801:Humans; D011485:Protein Binding; D051381:Rats; D013329:Structure-Activity Relationship; D014810:Vitamin E / Q000378:metabolism* / Q000627:therapeutic use; D014811:Vitamin E Deficiency / Q000209:etiology
D002352:Carrier Proteins; C017763:alpha-tocopherol transfer protein; D014810:Vitamin E