Decreased perceptual sensitivity to emotion-evoking stimuli in depression.
We measured two aspects of emotional response in depressed patients, as a preliminary study of the potential usefulness of such measures for elucidating pathophysiological mechanisms. First we used electromyography to measure the automatic mimicry on an individual's own face of facial displays of emotion observed on the faces of others. Next we used the fused dichotic listening paradigm to measure selective perception of both positive and negative emotion-related words as opposed to neutral words. Patients failed to show the normal facial mimicry of both positive and negative facial displays, despite normal cognitive processing of the stimuli. They also heard significantly fewer positive and negative words on the dichotic tests than did healthy controls. This suggests that depressed patients are hyposensitive to emotion-related stimuli in general.
Wexler
B E
BE
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519.
Levenson
L
L
Warrenburg
S
S
Price
L H
LH
D000328:Adult; D000367:Age Factors; D000368:Aged; D001288:Attention; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology*; D004007:Dichotic Listening Tests; D004576:Electromyography; D004644:Emotions; D005149:Facial Expression; D005152:Facial Muscles; D005260:Female; D006801:Humans; D007807:Language Tests; D008297:Male; D008875:Middle Aged; D010468:Perceptual Disorders / Q000209:etiology*; D010775:Photic Stimulation; D012737:Sex Factors