[Secondary sclerosing cholangitis and chemo-embolization with lipiodol].
Two cases of sclerosing cholangitis after oily arterial chemoembolization are reported. In one patient angiocholitis with liver abscesses, in the other patient gradual cholestasis were the main clinical features. In both cases, endoscopic retrograde cholangiogram showed a stricture of the common hepatic bile duct and, in one case, irregularities of intrahepatic biliary tree. Histologic examination of the liver in the two patients pointed out the involvement of small bile ducts and arteriolar endarteritis obliterans. Ischaemia is likely to be the main mechanism of these two cases of sclerosing cholangitis as well as in those described after FUDR intra-arterial chemotherapy. The prevalence of sclerosing cholangitis after arterial oily chemoembolization is probably underestimated because of a non specific clinical presentation and need to be precise by further study.
Service d'Hépato-Gastroentérologie, Hôpital Jean-Verdier, Bondy.
J P
JP
Richardet
T
T
Lons
M
M
Sibony
A
A
Choury
Y
Y
Ajavon
E
E
Coderc
S
S
Grimbert
Y
Y
Hecht
M
M
Beaugrand
D006528:Carcinoma, Hepatocellular / Q000628:therapy; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015209:Cholangitis, Sclerosing / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D004692:Endarteritis / Q000209:etiology / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006500:Hepatic Duct, Common / Q000000981:diagnostic imaging; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology; D007459:Iodized Oil / Q000009:adverse effects*; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy; D008297:Male; D008875:Middle Aged
D007459:Iodized Oil
Cholangite sclérosante secondaire et chimio-embolisation lipiodolée.