Ultrastructural study of an antibody-stabilized bladder surface: a new perspective on the elusive glycosaminoglycan layer.
The thin mucus or glycosaminoglycan layer of the bladder may be implicated in the pathogenesis of many bladder disease states. We have developed a specific antimucus, antisera stabilization technique to study the ultrastructural morphological appearance of the layer in both normal and abnormal bladders that should provide a new perspective on this elusive layer.
Department of Urology, Kingston General Hospital, Queen's University, Ontario, Canada.
J C
JC
Nickel
J
J
Cornish
D003556:Cystitis / Q000382:microbiology / Q000473:pathology; D006025:Glycosaminoglycans / Q000032:analysis*; D006801:Humans; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009092:Mucous Membrane / Q000648:ultrastructure; D009093:Mucus / Q000737:chemistry*; D001743:Urinary Bladder / Q000648:ultrastructure*
D006025:Glycosaminoglycans