[PCB concentration in hair, blood, tissues and secretions of chronically exposed dairy cows, fattening bulls and calves].
Fattening bulls (n = 8) and cows (n = 10) affected chronically with PCB were kept in barns on PCB-free feeding (silage, straw, concentrates). The cows were dried off. The kinetics of PCB-concentrations in hair, blood and feces were examined. Fattening bulls (mean 460 kg bw, german black and white and interbreeding german black and white and Simmental) with low (320 g) and medium (730 g) daily weight gain for a period of 5 months and 3 bulls with medium (640 g) weight gain within 18 months were examined. A drying off period of 3-5 months was recorded for the cows. The distribution of PCB in the carcass of some animals was registered in addition. The following results are to be emphasized: Reduction of PCB in the studied substrates in the fattening bulls depends on a high degree on daily weight gain. This is important in order to calculate biological half life times of PCB. By standardized weight gain of 10 kg in bulls, fed PCB-free diets for a 5 months period, a reduction of PCB-concentrations from 1 to 3% was found (hair and feces: 1%, blood 3%). Within a period of 18 months and with higher weights, in the examined substrates (blood, hair, feces) mean declines of the PCB-concentrations of 2% were found. On knowledge so far this value is an essential point to estimate biological half life times, because metabolic PCB-elimination is negligible.(ABSTRACT TRUNCATED AT 250 WORDS)
Klein
U
U
Nagorny
C
C
Forschner
E
E
Johannes
B
B
Drochner
W
W
D000818:Animals; D002417:Cattle / Q000378:metabolism*; D004350:Drug Residues / Q000493:pharmacokinetics*; D004781:Environmental Exposure; D005243:Feces / Q000737:chemistry; D005260:Female; D006197:Hair / Q000378:metabolism; D008297:Male; D011078:Polychlorinated Biphenyls / Q000097:blood / Q000493:pharmacokinetics*; D011247:Pregnancy
D011078:Polychlorinated Biphenyls
PCB-Konzentrationen in Haaren, Blut, Geweben und Ausscheidungen chronisch belasteter Milchkühe, Mastbullen und Kälber. 2. Mitteilung: Verlauf der Konzentration hochchlorierter Biphenyle (PCB) in Haaren, Geweben und Ausscheidungen chronisch belasteter Bullen und trockenstehender Kühe bei PCB-freier Fütterung.