Therapeutic thrombocytapheresis: a review of 132 patients.
Therapeutic thrombocytapheresis has been used is an attempt to obtain a rapid cytoreduction in thrombocythemic patients, in order to prevent or reduce thrombosis or bleeding complications. Long-term cytoreduction has to be performed with chemotherapy. We have treated with thrombocytapheresis 132 patients with increased platelet count (76 with thrombosis and/or bleeding) due to splenectomy, essential thrombocythemia and other myeloproliferative disorders: a comparative study has been performed to find a platelet count that could be helpful in preventing thrombotic and hemorrhagic complications and the role of diagnosis in predicting patient's risk.
Division of Immunohematology and Transfusion Services, Galliera Hospital, Genova, Italy.
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Adami
D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy; D010983:Plateletpheresis / Q000295:instrumentation; D011087:Polycythemia Vera / Q000628:therapy; D013922:Thrombocytosis / Q000628:therapy