Ultraviolet regulation of neuroendocrine and circadian physiology in rodents.
UV wavelengths can regulate neuroendocrine and circadian responses in some rodent species. Appropriately timed UV exposures can block the short photoperiod-induced collapse of the reproductive system, cause a rapid suppression of nocturnal melatonin synthesis, regulate melatonin rhythms and phase shift wheel running rhythms. These biological effects of UV are not dependent on the Harderian gland or melanin in the eye, but appear to be related to the degree of transmission through the ocular lens. Such results are consistent with the hypothesis that elements in the retina can transduce UV stimuli for circadian and neuroendocrine regulation.
Brainard
G C
GC
Department of Neurology, Jefferson Medical College, Philadelphia, PA 19107.
Barker
F M
FM
Hoffman
R J
RJ
Stetson
M H
MH
Hanifin
J P
JP
Podolin
P L
PL
Rollag
M D
MD
D000417:Albinism / Q000503:physiopathology; D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D006224:Cricetinae; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006243:Harderian Gland / Q000502:physiology*; D007908:Lens, Crystalline / Q000502:physiology; D008297:Male; D008550:Melatonin / Q000096:biosynthesis*; D008647:Mesocricetus; D010858:Pigmentation; D010870:Pineal Gland / Q000378:metabolism / Q000528:radiation effects*; D051381:Rats; D011919:Rats, Inbred Strains; D014466:Ultraviolet Rays
D008550:Melatonin