Ultrastructure of the neuromuscular junction of vasomotor nerves in the microvasculature of human dental pulp.
Vasomotor nerves in human dental pulp were more closely related to arterioles than to venules. Most were composed of unmyelinated fibres, which were mainly adrenergic. They appeared close to arterioles that were surrounded by a few layers of contractile smooth-muscle cells. The smaller arterioles with a diameter of 10-15 microns received a more intimate innervation by vasomotor nerves than did the larger. These vessels occasionally showed much narrower neuromuscular junctions than previously reported. Most of these nerve fibres were identified as adrenergic by the presence of chromaffin-positive synaptic vesicles detected by ultrastructural enzyme histochemistry. Their function appeared to be to regulate the blood flow and/or the blood pressure by stimulating smooth-muscle cells, resulting in contraction and a change in the calibre of the vessels. Capillaries and venules, which have a higher permeability, received weaker innervation by the vasomotor nerves than did arterioles. The intimate relation between vasomotor nerves and arterioles is related to the function of dental pulp in normal and pathological conditions.
Department of Oral Pathology, Fukuoka Dental College, Japan.
K
K
Okamura
I
I
Kobayashi
K
K
Matsuo
K
K
Taniguchi
Y
Y
Ishibashi
T
T
Izumi
H
H
Sakai
D000320:Adrenergic Fibers / Q000648:ultrastructure; D000328:Adult; D001160:Arterioles / Q000294:innervation; D001369:Axons / Q000648:ultrastructure; D001485:Basement Membrane / Q000648:ultrastructure; D002196:Capillaries / Q000294:innervation; D002799:Cholinergic Fibers / Q000648:ultrastructure; D003782:Dental Pulp / Q000098:blood supply* / Q000294:innervation*; D004730:Endothelium, Vascular / Q000166:cytology / Q000294:innervation; D006801:Humans; D008833:Microcirculation; D008854:Microscopy, Electron; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000166:cytology / Q000294:innervation; D009411:Nerve Endings / Q000648:ultrastructure; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure; D009469:Neuromuscular Junction / Q000648:ultrastructure*; D012583:Schwann Cells / Q000648:ultrastructure; D013572:Synaptic Vesicles / Q000648:ultrastructure; D014666:Vasomotor System / Q000648:ultrastructure*; D014699:Venules / Q000294:innervation