[Role of interleukin-10 in the regulation of immune responses in infectious diseases].
Interleukin-10 (IL-10) is a new anti-inflammatory and immunosuppressive cytokine produced in the course of several experimental and clinical infections. In this paper, we review the major properties of IL-10 in vitro and we discuss the role of endogenous IL-10 in the pathogenesis of infectious diseases.
Goldman
M
M
Service d'Immunologie, Hôpital Erasme et Université Libre de Bruxelles.
Marchant
A
A
Florquin
S
S
Velu
T
T
D000818:Animals; D001424:Bacterial Infections / Q000628:therapy; D004285:Dogs; D006801:Humans; D007239:Infections / Q000276:immunology* / Q000503:physiopathology; D016753:Interleukin-10 / Q000494:pharmacology / Q000502:physiology* / Q000627:therapeutic use; D010272:Parasitic Diseases / Q000628:therapy; D013602:T-Lymphocytes, Cytotoxic / Q000187:drug effects; D014777:Virus Diseases / Q000628:therapy
D016753:Interleukin-10
Rôle de l'interleukine-10 dans la régulation des résponses immunes en pathologie infectieuse.