[Disorder in the efficiency of oxygen release to the tissues from preserved human erythrocytes and the rate of its regeneration during their perfusion of the isolated heart].
The main hemodynamic and oxygen supply parameters of the isolated rat heart (128 experiments) were measured during its perfusion with human donor red cells differing by storage duration and kind of hemopreservatives. The degree of the reduction in efficacy of oxygen release to myocardial tissue and the speed of the release restoration depended both on the red cell storage time and the preservative composition. The authors advocate a new preservative citroglucophosphate with adenine as it proved superior to all the preservatives studied.
Iarochkin
V S
VS
Vinogradov
S M
SM
Suvorov
A V
AV
D000818:Animals; D001793:Blood Preservation; D004526:Efficiency / Q000502:physiology; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D009206:Myocardium / Q000378:metabolism*; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption; D010477:Perfusion; D051381:Rats; D013997:Time Factors
D010100:Oxygen
Narushenie éffektivnosti otdachi kisloroda tkaniam konservirovannymi éritrotsitami cheloveka i skorost' ee regeneratsii pri perfuzii imi izolirovannogo serdtsa.