[The sputum and detection of pulmonary carcinoma. III. Differential diagnosis of non-tumor lesions].
Diagnostic experience with cytology of the non-tumorous lung lesions imitating tumours by clinical investigation was presented. It concerned circulatory disturbances and inflammatory processes. Circulatory disturbances are characterized by erythrocytes and siderophages and often accompany tumours. On the other hand, impaired respiratory epithelial cells, regenerating cells of bronchiolar and alveolar lining can imitate non-small-cell type of carcinoma. Eosinophilic bronchial and peripheral lesions are characterized by increased number of eosinophils in addition to Charcot-Leyden crystals and respiratory epithelial cells. In case of their dysplasia with ciliocytophthoria and Creola bodies adenocarcinoma or large cell carcinoma can be suspected. Specific processes are mainly characterized by etiological agent, leukohistiocytic background and occasionally by other components of granulomatous inflammation. Perifocal and reparatory squamous metaplasia is to be distinguished from early squamous cancer. Presented lesions as well as other impairing reparative and reactive processes can result in exfoliation and occurrence of structures unusual for standard sputum. To classify them as class III-IV lesions would add to a false positivity.
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Ustav patologickej anatómie MFN a JLK UK, Martin.
D003581:Cytodiagnosis; D003937:Diagnosis, Differential; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis* / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013183:Sputum / Q000166:cytology*
Spútum a detekcia pl'úcnych karcinómov. III. Diferenciálna diagnostika nenádorových lézií.