Vision and ocular changes following accidental exposure to organophosphates.
The most conspicuous short-term effects of exposure to organophosphates are miotic pupils and a reduced visual field. Two men accidentally exposed to vapors of sarin, a cholinesterase inhibitor and extremely toxic nerve gas, showed these effects but no adverse effects on near- or far-visual acuities, oculomotor functions, intraocular pressure or color vision. However, reports of other accidental exposures to organophosphorus compounds suggest that there are visual and ocular changes, including myopia and decreased visual acuity.
Pennsylvania College of Optometry, Philadelphia.
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Rengstorff
D000059:Accidents; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D015877:Miosis / Q000139:chemically induced*; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure; D011680:Pupil / Q000187:drug effects; D012524:Sarin / Q000506:poisoning*; D014792:Visual Acuity / Q000187:drug effects*
D012524:Sarin