[The course of pregnancy induced by ovulation stimulation in patients with the hypogonadotropic form of amenorrhea].
The course of 60 pregnancies induced by ovulation stimulation with pergonal (in 46 cases) and lutrelef, an LHRF agonist (in 10 cases) was followed up. The authors emphasize the importance of the first therapeutic course as a preparative one, because pregnancies occurred in only 15 and 20% of patients treated with the two drugs, respectively, after it, and 25% of them failed to develop. The major pregnancy complications were due to multiple fetuses (23.4 and 20%, respectively). Stimulated pregnancy should be regarded as a high risk one in respect of spontaneous abortions; indications for abdominal delivery should be extended in such cases.
Sotnikova
E I
EI
Chernukha
E A
EA
Nazarenko
T A
TA
Tiutiunnik
V L
VL
Zykin
B I
BI
D000033:Abortion, Threatened / Q000453:epidemiology; D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008596:Menotropins / Q000008:administration & dosage; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D010062:Ovulation Induction / Q000379:methods / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D011272:Pregnancy, Multiple / Q000187:drug effects
D007987:Gonadotropin-Releasing Hormone; D008596:Menotropins
Techenie beremennosti, indutsirovannoĭ stimuliatsieĭ ovuliatsii u patsientok s gipogonadotropnoĭ formoĭ amenorei.