[Cytosol estrogen and progesterone receptors in female genital system malignant tumors].
Specimens from 344 cases of endometrial carcinoma, 289 cases of ovarian carcinoma, 177 cases of cervical carcinoma, 10 vulva and 4 fallopian tube carcinoma were assayed for cytosol estrogen and progesterone receptor (ER, PR) contents with dextran-coated charcoal (DCC) method. Positive rates of ER and PR in these malignant tumors in relation to menstrual cycle, histological differentiation, clinical stage and prognosis of disease were studied. The results suggested that the contents of ER and PR may play a role in building endocrine therapy and prognosis in the postoperative period. Further study on vulvar and fallopian tube carcinomas should be undertaken.
Second University Hospital, West China University of Medical Sciences, Chengdu.
S W
SW
Han
B
B
He
Q P
QP
Tang
D000230:Adenocarcinoma / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D016889:Endometrial Neoplasms / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism*; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism*; D002583:Uterine Cervical Neoplasms / Q000378:metabolism*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone