In search of cytokine-response genes.
The development of efficient cloning methods for the isolation of cytokine-response genes is vital to our understanding of how cytokines elicit distinct cellular responses. Here, Carol Beadling and Kendall Smith describe a straightforward and rapid method that has been used to clone interleukin 2 (IL-2)-induced genes.
Imperial Cancer Research Fund, London, UK.
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D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology; D005786:Gene Expression Regulation / Q000187:drug effects*; D006801:Humans; D007376:Interleukin-2 / Q000494:pharmacology*; D012333:RNA, Messenger / Q000187:drug effects
D007376:Interleukin-2; D012333:RNA, Messenger; D003513:Cycloheximide