Diagnostic value of indirect pancreatic function test in serum of anuric patients with chronic renal failure.
Although patients with chronic renal failure have a high incidence of chronic pancreatic disease, the condition is frequently overlooked. We have modified the pancreolauryl test--an indirect pancreatic function test--for anuric patients. The test permitted good discrimination between patients with chronic pancreatic disease and those with a normal pancreas when serum levels of fluorescein were measured 10 h after administration with a standard meal. The sensitivity at this time interval was 80% and the specificity 83%. We conclude that the pancreolauryl test with serum measurements provides a simple, noninvasive, and reliable diagnostic test for chronic pancreatic disease in anuric patients with chronic renal failure.
Department of Medicine III, Medical Faculty, Aachen Technical University, Germany.
M M
MM
Lerch
I
I
Nolte
J
J
Riehl
U
U
Gladziwa
H
H
Mann
H G
HG
Sieberth
S
S
Matern
D001002:Anuria / Q000097:blood / Q000150:complications; D002908:Chronic Disease; D005452:Fluoresceins / Q000032:analysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000652:urine
D005452:Fluoresceins