[Type I allergy and indices of immune response in patients with ulcerative colitis].
In a group of 24 patients with ulcerative colitis and in 15 persons in the control group allergological studies were carried out which included history taking, cutaneous tests, assessment of total concentration and presence of specific IgE in the serum, and selected immune response indices (Ig levels, immune complex concentration and numbers of T- and B-cells). In our studies it was found that in two-thirds of patients with ulcerative colitis clinical reactions after meal occurred, in 54% atopy coexisted, and immunological abnormalities occurred more frequently than in the control group. Our studies proved that the role of various reactions to consumed meal, including early allergic reactions, cannot be rejected with full certainty. A number of indirect evidence that type I allergy according to Gell and Coombs, and immunological abnormalities participated in the pathological mechanism of that disease was also found.
Katedry i Kliniki Gastroenterologii i Chorób Wewnetrznych Ak. Med., Bydgoszczy.
M
M
Swiatkowski
M
M
Kłopocka
K
K
Suppan
D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000276:immunology*; D005260:Female; D005512:Food Hypersensitivity / Q000276:immunology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D008297:Male; D008875:Middle Aged
Alergia typu I oraz wskaźniki odpowiedzi immunologicznej u chorych na wrzodziejace zapalenie jelita grubego.