[Histological changes in ligated stumps of ovarian blood vessels in preventive preoperative low-dose heparin administration].
The blood coagulation processes in ligated vasa ovarica after preoperative injection of low-dose standard heparin were examined in 30 women during abdominal hysterectomy and adnexectomy. We resected the stumps after 30 min. Histological examination revealed that in 20% of the arteries and in 30% of the veins there were blood coagulation processes of different extent near the ligation only. The final vascular occlusion is mainly achieved via locally limited damage of vessels and endothelial cells which leads to a direct and quick obliteration of the lumen by proliferation of tissue fibroblasts.
Slunsky
R
R
Abteilung für Frauenheilkunde und Geburtshilfe, Krankenhaus Klosterneuburg, Osterreich.
D001158:Arteries / Q000187:drug effects / Q000473:pathology; D001777:Blood Coagulation / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects / Q000473:pathology; D005260:Female; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007044:Hysterectomy; D007889:Leiomyoma / Q000473:pathology / Q000601:surgery; D008026:Ligation; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery; D010052:Ovariectomy; D010053:Ovary / Q000098:blood supply*; D011292:Premedication; D013924:Thrombophlebitis / Q000473:pathology / Q000517:prevention & control*; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery; D014680:Veins / Q000187:drug effects / Q000473:pathology; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology
D006493:Heparin
Histologische Veränderungen in den unterbundenen Stümpfen der Ovarialgefässe bei präoperativer niedrigdosierter Heparinprophylaxe.