Ichthyosis hystrix and skin cancer.
Ichthyosis hystrix is a rare genodermatosis characterized by persistent spiny scales which cover a significant part of the skin surface. In many cases it is associated with palmoplantar keratoderma, and occasionally deafness and neurological defects coexist. The case of a man with ichthyosis hystrix is reported who developed skin malignancy and dysplastic keratoses, a complication which has not previously been recorded.
St John's Dermatology Centre, St Thomas' Hospital, London, UK.
M R
MR
Judge
D H
DH
McGibbon
D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology; D005385:Fingers / Q000473:pathology; D006801:Humans; D007057:Ichthyosis / Q000150:complications* / Q000473:pathology; D007868:Leg Dermatoses / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology