Regulation of gene expression at early stages of B-cell differentiation.
The phenotype of B lymphocytes at various stages of differentiation is, in part, controlled at the transcriptional level. Recently, a number of B-cell lineage and stage-specific transcription factors have been identified as candidate determinants for the developmental regulation of gene expression in B lymphocytes.
Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco 94143-0414.
J
J
Hagman
R
R
Grosschedl
D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology*; D001483:Base Sequence; D002454:Cell Differentiation / Q000502:physiology*; D004742:Enhancer Elements, Genetic; D005786:Gene Expression Regulation / Q000502:physiology*; D018257:Helix-Loop-Helix Motifs / Q000502:physiology; D007107:Immune System / Q000254:growth & development; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D014157:Transcription Factors / Q000502:physiology
D014157:Transcription Factors