Retro-binding tripeptide thrombin active-site inhibitors: discovery, synthesis, and molecular modeling.
Iwanowicz
E J
EJ
Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543-4000.
Lau
W F
WF
Lin
J
J
Roberts
D G
DG
Seiler
S M
SM
D000595:Amino Acid Sequence; D001665:Binding Sites; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000378:metabolism; D015842:Serine Proteinase Inhibitors / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship; D013917:Thrombin / Q000037:antagonists & inhibitors* / Q000378:metabolism
D009842:Oligopeptides; D015842:Serine Proteinase Inhibitors; D013917:Thrombin