[The morphogenesis of the tunica elastica interna of the rat aorta in the early periods after birth].
The ultrastructural and three-dimensional spatial arrangement of the internal elastic membrane (IEM) of the rat's aorta was studied by transmissive electron microscopy, native and scanning electron microscopy of chemically extracted specimens. Changes in the passage of different levels of organization of IEM is shown in the process of its maturation in postnatal ontogenesis. The first--fibrillar--step of morphogenesis of IEM is characterized by the formation of microfibril fascicles in 10-day-old animals. Within 1 month after birth the elastic fiber of the lamellar shape was formed which consists of tightly packed fascicles of microfibrils. This fiber is a structural-functional unit of the elastic framework of the aorta. The last stage is characterized by the formation of the tissue system of the fibrous elastic framework consisting of elastic fibers which are structurally interconnected and are having functional interaction. The formation of openings (pores) in IEM is a regular stage of clastogenesis. Through the pores in EM a contact of endotheliocytes and smooth myocytes (SM) is realized, by means of which a system is formed responsible for the transmission of information from receptors on the surface of endotheliocytes to SM. A stereometric analysis has revealed the dynamics of pore distribution density in IEM in the process of its maturation.
Salapina
O A
OA
Mironov
A A
AA
D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D001011:Aorta / Q000254:growth & development / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009024:Morphogenesis; D051381:Rats; D017208:Rats, Wistar; D017539:Tunica Intima / Q000254:growth & development / Q000648:ultrastructure*
Morfogenez vnutrenneĭ élasticheskoĭ membrany aorty krys v rannie periody posle rozhdeniia.