Auditory-evoked dipole source activity as indicator of withdrawal severity in alcoholic patients.
The relationship between auditory-evoked potentials and the ethanol withdrawal syndrome was investigated in alcoholic inpatients using dipole source analysis. It was found that the increase in N1/P2 amplitude during withdrawal was positively correlated to the general severity of the withdrawal, but not to single symptoms such as seizures. Monitoring of initial changes in the auditory-evoked N1/P2 amplitude may be of predictive value concerning the withdrawal severity of alcoholic patients.
Laboratory of Clinical Psychophysiology, Free University of Berlin, Germany.
G
G
Juckel
A
A
Frota
J
J
Gallinat
L G
LG
Schmidt
H
H
Rommelspacher
U
U
Hegerl
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications* / Q000503:physiopathology; D000431:Ethanol / Q000097:blood; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology*
D000431:Ethanol