Analysis of systems influencing renal hemodynamics and sodium excretion. I. Biochemical systems theory.
In this article we present a new methodology--Biochemical Systems Theory and Analysis--as an alternative to traditional parametric statistical procedures for investigating differences between risk groups in a population. We review the systems theory and how it can be used to represent a model of processes influencing renal hemodynamics and sodium (Na+) excretion. We also discuss the potential for new measures of the biology of common diseases that can emerge from a synergism between systems theory and population-based statistical approaches.
Reilly
S L
SL
University of Michigan Medical School, Ann Arbor.
Sing
C F
CF
Savageau
M A
MA
Turner
S T
ST
D001794:Blood Pressure / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007668:Kidney / Q000098:blood supply*; D015233:Models, Statistical; D012084:Renin-Angiotensin System / Q000502:physiology; D012964:Sodium / Q000652:urine*; D013598:Systems Theory; D014882:Water-Electrolyte Balance / Q000502:physiology*
D012964:Sodium