[Prognostic aspects of esophageal ph-metry in infants with reflux].
Gastroesophageal reflux (g.e.r.) is a very common event in children particularly in infants. Twenty-four-hour continuous esophageal pH monitoring has become the preferred test to quantify acid gastroesophageal reflux. It has a large sensitivity and specificity, but it does not allow a good prediction of esophagitis. The Authors show a computerized method to determine the area under the curve (a.u.c.) and the percentage of time at different pH levels. These parameters have shown the same sensitivity and specificity as DeMeester-Boix-Ochoa score. They directly relate the time of exposure and pH level in every reflux under pH 4 and so they suggest a better prognostic index. To improve this approach to g.e.r. we will need other studies with this method.
Istituto di Puericultura e Pediatria Sociale, Università degli Studi di Siena, Italia.
G
G
Tota
A
A
Garzi
M
M
Strambi
D
D
Meucci
G
G
Di Maggio
A
A
Iroatulam
M
M
Messina
D000367:Age Factors; D004947:Esophagus / Q000502:physiology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008991:Monitoring, Physiologic; D011379:Prognosis
Aspetti prognostici nella pHmetria esofagea del lattante reflussore.