[Transfer of photosensitive epilepsy of genetic origin by selective grafts of brain vesicles in chick embryo].
We transferred the avian photosensitive genetic epilepsy to normal chicken by transplanting at least prosencephalic and mesencephalic vesicles from epileptic to normal chick embryos at day 2 of incubation. Chimeras showed typical interictal EEG and developed, under intermittent light stimulation, seizures phenotypically and electrically similar to the epileptic strain seizures.
Institut d'Embryologie Cellulaire et Moléculaire, CNRS-UMRC, Nogent-sur-Marne.
M A
MA
Teillet
N
N
Guy
B
B
Schuler
G
G
Le Gal La Salle
C
C
Batini
N
N
Le Douarin
R
R
Naquet
D000818:Animals; D002642:Chick Embryo; D004827:Epilepsy / Q000235:genetics*; D008027:Light; D008636:Mesencephalon / Q000637:transplantation*; D016548:Prosencephalon / Q000637:transplantation*; D012249:Rhombencephalon / Q000637:transplantation; D018183:Transplantation Chimera
Transfert d'une épilepsie photosensible d'origine génétique par greffes sélectives de vésicules cérébrales chez l'embryon de Poulet.