Surface coil cardiac tagging and 31P spectroscopic localization with B1-insensitive adiabatic pulses.
A technique is presented for MRI tagging in the presence of inhomogeneous B1 fields. A rectangular tagging grid is produced with B1-insensitive adiabatic pulses in a magnetization preparation period that precedes image acquisition. Phantom results demonstrate that the method is well-suited to surface coil experiments. The technique is applied to a canine model of myocardial ischemia to track the spatially dependent wall motion of the left ventricle during the cardiac cycle. Transmural 31P spectra are acquired from the same double-tuned surface coil, with tagging and spectroscopy performed for the first time, during normal, ischemic, and recovery conditions for the same animal.
Hendrich
K
K
Department of Biochemistry, University of Minnesota Medical School, Minneapolis 55455.
Xu
Y
Y
Kim
S G
SG
Uğurbil
K
K
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D003331:Coronary Vessels / Q000502:physiology; D003971:Diastole / Q000502:physiology; D004285:Dogs; D005583:Fourier Analysis; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008280:Magnetics; D008955:Models, Cardiovascular; D008961:Models, Structural; D017202:Myocardial Ischemia / Q000378:metabolism*; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism; D010758:Phosphorus; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology
D010710:Phosphates; D010725:Phosphocreatine; D010758:Phosphorus; D000255:Adenosine Triphosphate