Advanced prostatic carcinoma in a 19-year-old male.
We report a case of poorly differentiated carcinoma of the prostate with lymph node metastasis in a 19-year-old male. He was managed with bilateral orchiectomy, flutamide and recombinant interferon alfa-2b therapy. He showed subjective improvement for 2 months. However, during the 3rd month of treatment there was global deterioration which progressed further till his demise during the 4th month. The beneficial role, if any, of combined hormonal and immunotherapy in advanced prostatic carcinoma is discussed as also the natural history and prognosis of prostatic carcinoma in men under 20 years of age.
Jindal
P K
PK
Department of Urology, Post-Graduate Institute of Medical Education and Research, Chandigarh, India.
Hota
D
D
Prasad
K V
KV
Nijhawan
R
R
Vaidyanathan
S
S
D000328:Adult; D002277:Carcinoma / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005485:Flutamide / Q000627:therapeutic use; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D008207:Lymphatic Metastasis; D008297:Male; D009919:Orchiectomy; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D011994:Recombinant Proteins
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D005485:Flutamide