Profound reversible CD4+ T lymphocytopenia in a severely uremic patient.
We report a human immunodeficiency virus antibody-negative, profoundly uremic patient who presented with a CD4+ T lymphocyte count of 133/mm3, a CD8+ T lymphocyte count of 77/mm3, and a CD3+ T lymphocyte count of 259/mm3. These values decrease significantly below reported levels in other lymphopenic uremic patients. High-efficiency chronic hemodialysis resulted in correction of these cytopenias to a normal range within 12 weeks.
Polsky
F I
FI
Department of Internal Medicine, Utah Valley Regional Medical Center, Provo 84604.
Dannemann
B
B
Hemmert
W H
WH
D000328:Adult; D006801:Humans; D008231:Lymphopenia / Q000150:complications*; D008297:Male; D006435:Renal Dialysis; D013601:T-Lymphocytes; D014511:Uremia / Q000150:complications* / Q000628:therapy