PINV--topography and primary negative symptoms in chronic schizophrenia.
PINV was recorded during a warned reaction time paradigm in 16 chronic schizophrenics in remission. Clinical symptoms were assessed by BPRS, SANS, and the anhedonia scale of the Chapman Questionnaire. Ten healthy controls were studied in the same manner. Over the frontocentral area we found a significantly elevated PINV amplitude with an altered topographical distribution in the patient group. The difference values "PINVCz-PINVFz" were correlated negatively with primary negative symptoms of schizophrenia.
Department of Psychiatry, ZKH Reinkenheide, Bremerhaven, Germany.
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G
Eikmeier
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Lodemann
D000328:Adult; D002908:Chronic Disease; D003265:Contingent Negative Variation / Q000502:physiology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D011930:Reaction Time / Q000502:physiology; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology