[The choice of adequate criteria for the vitamin B6 allowance of the human body].
Correlations between indicators of vitamin B6 supply of the body were studied: blood plasma pyridoxal phosphate (PP) level, red cell basal specific activity of aspartate aminotransferase (AsAT), PP effect, urinary excretion of 4-pyridoxilic acid (4-PA). In normal riboflavin supply of the body all the four indicators are in good correlation and may be regarded as criteria of vitamin B6 supply. Blood plasma PP concentration over 8.5 ng/ml, urinary excretion of 4-PA more than 60 micrograms/h should be used as the lower thresholds of the normal range in high-pressure liquid chromatography. Red cell AsAT activity and the magnitude of PP effect depending on specific conditions (storage, hemolysate dilution, substrate concentration, etc.), their use is permissible only after standardization of these conditions and setting up the values conforming to the norm for the specific conditions of AsAT activity measurements. Under conditions of our studies PP effect magnitude more than 2 points to vitamin B6 deficit.
V M
VM
Kodentsova
N A
NA
Beketova
V V
VV
Risnik
A A
AA
Sokol'nikov
O A
OA
Vrzhesinskaia
V B
VB
Spirichev
D000293:Adolescent; D000328:Adult; D001219:Aspartate Aminotransferases / Q000097:blood; D002648:Child; D002851:Chromatography, High Pressure Liquid; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D011732:Pyridoxal Phosphate / Q000097:blood; D011735:Pyridoxic Acid / Q000652:urine; D011736:Pyridoxine / Q000378:metabolism*; D012016:Reference Values
D011735:Pyridoxic Acid; D011732:Pyridoxal Phosphate; D001219:Aspartate Aminotransferases; D011736:Pyridoxine
K vyboru adekvatnykh kriteriĭ obespechennsoti organizma cheloveka vitaminom B6.