[Zn-content of erythrocytes in overt and subclinical hyperthyroidism].
Assaying the markers in blood reflecting thyroid hormone effect at peripheral tissue level previous data revealing a significantly decreased red-blood cell Zn-content in overt hyperthyroidism compared to euthyroid controls could be confirmed (p < 0.001). In patients with thyrotoxicosis during Metothyrin treatment the Zn-concentration of red-blood-cells normalised about 8 weeks later than the abnormally elevated serum thyroxine and triiodothyronine levels. On the basis of the present findings it is assumed that the Zn-concentration of red-blood cells reflects to a certain degree the circulating levels of thyroid hormones 2 to 3 months prior to the performed examination. The measurement of red-blood cell Zn-content does not seem to be a reliable method for the detection of a possible "tissue"-thyrotoxicosis in cases of subclinical hyperthyroidism.
Semmelweis Orvostudományi Egyetem, I. Belklinika, Budapest.
F
F
Varga
G
G
Tarján
K
K
Steczek
J
J
Földes
D004912:Erythrocytes / Q000737:chemistry; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood*; D013053:Spectrophotometry; D016606:Thyroid Nodule / Q000097:blood; D013971:Thyrotoxicosis / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D015032:Zinc / Q000097:blood*
D014284:Triiodothyronine; D013972:Thyrotropin; D015032:Zinc; D013974:Thyroxine
Vörösvérsejt Zn-tartalom vizsgálata manifeszt és szubklinikus hyperthyreosisban.