[Effect of vinylsorb SS on the morphology and coagulability of blood during perfusion in vitro].
In the paper the changes appearing in in vitro during perfusion of citrated blood through a column filled with Vinylsorb SS in temperature of 22 and 37 degrees C were evaluated. In both temperatures there was a slight decrease of the number of leucocytes and thrombocytes, both in the examined and the control system. The remaining number of thrombocytes ensured hemostasia. The authors think that the main factor causing decrease of the number of morphotic elements of blood as well as activating slightly coagulation system was the effect of drains, a peristaltic pump, blood container and perfusion column and not the sorbent. Vinylsorb turned out to be a good and safe sorbent which should be applied in the process of hemoperfusion in people.
Katedra i Zakład Patofizjologii Akademii Medycznej, Bydgoszczy.
P
P
Jurkowski
M
M
Cwiklińska-Jurkowska
M
M
Kotschy
E
E
Zekanowska
D000327:Adsorption; D001672:Biocompatible Materials; D001777:Blood Coagulation / Q000187:drug effects*; D006464:Hemoperfusion / Q000295:instrumentation*; D006801:Humans; D066298:In Vitro Techniques; D007958:Leukocyte Count / Q000187:drug effects; D010976:Platelet Count / Q000187:drug effects; D011137:Polystyrenes / Q000494:pharmacology*; D011145:Polyvinyls / Q000494:pharmacology*; D013696:Temperature
D001672:Biocompatible Materials; D011137:Polystyrenes; D011145:Polyvinyls; C088284:vinylsorb SS
Wpływ vinylsorbu SS na morfologie i krzepliwość krwi podczas perfuzji in vitro.