Pharmaco-toxicological expert report Pulmozyme rhDNase Genentech, Inc.
Green
J D
JD
Genentech, Inc., South San Francisco, California.
D000280:Administration, Inhalation; D000818:Animals; D000917:Antibody Formation; D001682:Biological Availability; D003550:Cystic Fibrosis / Q000188:drug therapy*; D003850:Deoxyribonuclease I / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use / Q000633:toxicity*; D004355:Drug Stability; D005123:Eye / Q000187:drug effects; D000882:Haplorhini; D006801:Humans; D007275:Injections, Intravenous; D009152:Mutagenicity Tests; D051381:Rats; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use / Q000633:toxicity; D012449:Safety; D013045:Species Specificity; D013183:Sputum / Q000187:drug effects; D014018:Tissue Distribution
D011994:Recombinant Proteins; C085693:DNASE1 protein, human; D003850:Deoxyribonuclease I