Improvement of olfaction following pansinus surgery.
This study involves ten consecutive anosmic patients who underwent pansinus surgery and have been followed and tested a minimum of one year. They all had advanced obstructive bilateral nasal polyposis and pansinusitis. Persistent severe loss of smell was one of the chief complaints in all ten patients. The surgery performed included bilateral nasal polypectomies, bilateral sphenoidethmoidectomies and bilateral nasal antral windows. Post-operatively, all were treated with a topical corticosteroid nasal spray. Seven of these patients were asthmatic and three were also aspirin-sensitive, some being cortisone-dependent. The University of Pennsylvania Smell Identification Test (UPSIT) was administered pre-operatively and then at six-month intervals in the post-operative period. Significant initial improvement in smell acuity occurred in seven of the ten patients. One of the seven, however, developed recurrence of the nasal polyposis and again lost his smell capabilities somewhere between the twelfth and eighteenth post-operative months. Another of the patients who did not improve smell sensitivity post-operatively occasionally is aware of fleeting periods of return.
Eichel
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D000281:Administration, Intranasal; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000150:complications / Q000601:surgery*; D000857:Olfaction Disorders / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D010256:Paranasal Sinuses / Q000601:surgery*; D012903:Smell; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones