[Determination of functional activity of lymphocytes in patients with tuberculosis and in patients of group IIIA of clinic registries by electrophoretic mobility].
The electrophoretic mobility of peripheral blood lymphocytes was studied in 35 patients with pulmonary tuberculosis, 128 persons clinically cured of tuberculosis, and 30 healthy persons by using an Elphor-VaP-5 apparatus (Germany). This study revealed abnormal lymphocytic functional activity both in patients with tuberculosis and in patients with great residual changes after prior tuberculosis, which was the basis for using of thymic immunomodulators (thymalin or thymogen) in the latters. Immunomodulators improved the tolerance of antirecurrent chemotherapy in persons with IIIA dispensary register group and produced a marked stimulating effect on the functional activity of T and B lymphocytes.
Morozova
T I
TI
Khudzik
L B
LB
Tikhomirova
L A
LA
D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology* / Q000502:physiology; D004586:Electrophoresis; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D012042:Registries; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology* / Q000502:physiology; D014397:Tuberculosis, Pulmonary / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology
D000276:Adjuvants, Immunologic
Opredelenie funktsionalńoĭ aktivnosti limfotsitov u bolńykh tuberkulëzom i u lits IIIA gruppy dispansernogo uchëta po élektroforeticheskoĭ podvizhnosti.