The effects of donor age and strain rate on the biomechanical properties of bone-patellar tendon-bone allografts.
Over 50% of all knee injuries involve partial or complete tear of the anterior cruciate ligament. Surgical reconstruction of this ligament using an isometrically placed bone-patellar tendon-bone autograft is the current technique of choice; however, harvest of patellar tendon as a free graft can lead to increased morbidity. To address this issue, allogenic patellar tendon grafts have been introduced as alternatives to autogenic graft material. The purpose of this study was to examine effects of age and strain rate on tensile strength, modulus, and failure mode of bone-patellar tendon-bone allografts from a typical population of tissue donors. Eighty-two, fresh-frozen, bone-patellar tendon-bone allografts were harvested from 25 different donors, aged 17 to 54. Paired grafts from individual patellar tendons were assigned randomly to tensile testing at either 10% or 100% elongation per second. Tensile strength, modulus, and failure mode were not significantly different for tests conducted at these 2 strain rates. Correlations between tensile strength and age were not significant for tests conducted at either strain rate. Specimens tested at a strain rate of 100% per second exhibited weak but significant negative correlation between modulus and age, with modulus decreasing 25% over the age range examined.
Blevins
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FT
Orthopaedic Biomechanics Laboratory, Charles A. Dana Research Institute, Beth Israel Hospital, Boston, Massachusetts 02215.
Hecker
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Bigler
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Boland
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Hayes
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WC
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology*; D001696:Biomechanical Phenomena; D016025:Bone Transplantation / Q000473:pathology / Q000502:physiology*; D004548:Elasticity; D005260:Female; D050723:Fractures, Bone / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017847:Patellar Ligament / Q000473:pathology / Q000502:physiology / Q000637:transplantation*; D013314:Stress, Mechanical; D013718:Tensile Strength; D013977:Tibia / Q000473:pathology / Q000502:physiology / Q000601:surgery; D014019:Tissue Donors; D014184:Transplantation, Homologous