Teaching active transport at the turn of the twenty-first century: recent discoveries and conceptual changes.
The conceptual advances introduced by recent discoveries in the field of active transport have triggered a transition from a "black box" approach to a "mechanistic" approach. At present, treating this subject in the graduate setting requires consideration of equilibrium and kinetic experimentation, protein chemistry, mutational analysis and molecular structure, with the aim of defining the "transport machine."
Department of Biological Chemistry, University of Maryland School of Medicine, Baltimore 21201.
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D000818:Animals; D001693:Biological Transport, Active; D001703:Biophysics / Q000193:education* / Q000639:trends; D000252:Calcium-Transporting ATPases / Q000737:chemistry / Q000378:metabolism; D017136:Ion Transport; D008024:Ligands; D008954:Models, Biological; D008958:Models, Molecular; D012519:Sarcoplasmic Reticulum / Q000378:metabolism; D013379:Substrate Specificity
D008024:Ligands; D000252:Calcium-Transporting ATPases