Identification of a gene encoding a new Ypt/Rab-like monomeric G-protein in Saccharomyces cerevisiae.
A Saccharomyces cerevisiae sequence cloned by serendipity was found to encode a protein that is a new member of the Ypt/Rab monomeric G-protein family. This sequence shows high homology to the yeast genes SEC4 and YPT1 and, like SEC4 and YPT1, is essential for viability. The sequence was localized to chromosome V based upon hybridization to pulse-field gel-separated yeast chromosomes. The sequence has been deposited in the GenBank data library under Accession Number L17070.
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American Cyanamid, Agricultural Reseach Division, Princeton, NJ 08543-0400.
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Kirsch
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D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D019204:GTP-Binding Proteins / Q000235:genetics*; D005800:Genes, Fungal / Q000235:genetics*; D005804:Genes, Lethal / Q000235:genetics; D011905:Genes, ras / Q000235:genetics; D008969:Molecular Sequence Data; D011487:Protein Conformation; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins; D017386:Sequence Homology, Amino Acid; D020691:rab GTP-Binding Proteins
D029701:Saccharomyces cerevisiae Proteins; C087905:YPT31 protein, S cerevisiae; D019204:GTP-Binding Proteins; C060755:YPT1 protein, S cerevisiae; C064320:SEC4 protein, S cerevisiae; D020691:rab GTP-Binding Proteins