Biochemical differences (O-acetyl and glycolyl groups) in erythrocyte surface sialic acids of trypanotolerant N'dama and trypanosusceptible Zebu cattle.
Differences in the distribution and concentration of O-acetyl and glycolyl groups in erythrocyte sialic acids of trypanotolerant N'dama and trypanosusceptible Zebu cattle were investigated. Erythrocyte surface sialic acid concentrations were 25.4 +/- 5.5 mg per dl and 5.9 +/- 0.97 mg per dl in N'dama and Zebu animals, respectively. In N'damas, O-acetyl and glycolyl groups were present in concentrations of 16.4 +/- 4.3 mg per dl and 12.8 +/- 2.9 mg per dl, respectively, whereas the corresponding values in Zebus were 2.8 +/- 5.0 mg per dl and 7.6 +/- 1.7 mg per dl, respectively. The differences between N'dama and Zebu cattle in surface sialic acids and in O-acetyl and glycolyl groups were significant (P < 0.01 to < 0.001). N'dama erythrocyte sialic acids had more O-acetyl than glycolyl groups while those of Zebus had less O-acetyl than glycolyl groups. These findings may be relevant to the trypanotolerance of N'dama cattle.
Department of Veterinary Pathology and Microbiology, Ahmadu Bello University, Zaria, Nigeria.
A
A
Shugaba
I
I
Umar
J
J
Omage
N D
ND
Ibrahim
J
J
Andrews
A I
AI
Ukoha
D I
DI
Saror
K A
KA
Esievo
D000107:Acetylation; D000818:Animals; D001798:Blood Proteins / Q000737:chemistry*; D002417:Cattle; D004198:Disease Susceptibility / Q000097:blood / Q000662:veterinary; D004910:Erythrocyte Membrane / Q000737:chemistry*; D006031:Glycosylation; D008562:Membrane Glycoproteins / Q000097:blood*; D012794:Sialic Acids / Q000097:blood*; D014354:Trypanosomiasis, Bovine / Q000097:blood*
D001798:Blood Proteins; D008562:Membrane Glycoproteins; D012794:Sialic Acids