FL-120A-D', new products related to kinamycin from Streptomyces chattanoogensis subsp. taitungensis subsp. nov. II. Isolation and structure determination.
Six new kinamycin antibiotics have been isolated from the culture filtrate of Streptomyces chattanoogensis. The structures of six related components were determined employing 1D and 2D NMR spectroscopy and mass spectrometry. These structures represent the first reported epoxide kinamycin (2, 3) and propionyl derivative of kinamycin (5), and new isobutyryl derivatives of kinamycin (1, 4, 6).
Division of Applied Chemistry, National Defense Medical Center, Taipei, Taiwan, R.O.C.
J J
JJ
Young
S N
SN
Ho
W M
WM
Ju
L R
LR
Chang
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification; D018360:Crystallography, X-Ray; D004852:Epoxy Compounds / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D015394:Molecular Structure; D013055:Spectrophotometry, Infrared; D000095602:Angucyclines and Angucyclinones
D000900:Anti-Bacterial Agents; D002227:Carbazoles; D004852:Epoxy Compounds; C088443:FL 120B'; C088444:FL 120C; C088445:FL 120C'; C088442:kinamycin D; D000095602:Angucyclines and Angucyclinones