[Cognitive impact of antidepressants].
This review aims to synthesize informations about the cognitive effects of antidepressants, eg memory, attention and psychomotor functions. The specific cognitive profile of each compound relies on its biochemical action, particularly with its anticholinergic or noradrenergic properties. Some of these treatments can produce sedative or dysmnesic impact while on the other hand others can have no cognitive impact or even produce a stimulating effect. This analysis tends to facilitate a good clinical prescription by summarizing all the different cognitive effects of antidepressants, regarding the type of the population selected (healthy volunteers or depressed patients), their age and the duration of the prescription (acute dose or long-term treatment). Finally general advices are preconized to avoid a decrease in cognitive efficiency when an antidepressant treatment is introduced.
Service Hospitalo-Universitaire de Santé Mentale et de Thérapeutique, Hôpital Sainte-Anne, Paris.
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I
Amado-Boccara
J M
JM
Danion
D000293:Adolescent; D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001288:Attention / Q000187:drug effects; D003071:Cognition / Q000187:drug effects*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008297:Male; D011939:Mental Recall / Q000187:drug effects; D008875:Middle Aged; D011597:Psychomotor Performance / Q000187:drug effects; D012016:Reference Values
D000928:Antidepressive Agents
Incidence cognitive des antidépresseurs.