[Immunologic and non-specific reactivity in patients with chronic suppurative obstructive bronchitis and its effect on the course of disease].
A total of 32 patients with aggravated chronic pyo-obstructive bronchitis were studied. Various immunological disorders and impaired non-specific responsiveness were detected in this group of patients. With this, abnormal T cellular immunity (reduced T cell counts at the expense of T helpers and their reaction to PGA) was the leading T cell immunity disorder. In the presence of the available immunity abnormalities, responses to inflammation (B-systems) and non-specific responsiveness were less pronounced. During treatment, the patients without substantial immunity disorders had normalized parameters of immunity and non-specific responsiveness, whereas the patients displayed this. The clinical efficacy of treatment was higher in patients without significant abnormalities in immunity and non-specific responsiveness.
Litvinova
N V
NV
Eremeev
V V
VV
Abramova
Z P
ZP
Kulikovskaia
N V
NV
Gergert
V Ia
VIa
D001402:B-Lymphocytes / Q000276:immunology*; D001991:Bronchitis / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D008297:Male; D008875:Middle Aged; D013492:Suppuration; D013601:T-Lymphocytes / Q000276:immunology*; D013997:Time Factors; D016896:Treatment Outcome
Immunologicheskaia i nespetsificheskaia reaktivnost bolńykh khronicheskim gnoĭno-obstruktivnym bronkhitom i eë vliianie na techenie zabolevaniia.