Nephrotic syndrome as an unusual paraneoplastic syndrome of Hodgkin's disease demonstrated on gallium-67 scan.
Nephrotic syndrome, although rare, is recognized as one of the paraneoplastic syndromes. A patient with documented Hodgkin's disease showed increased uptake of Ga-67 in the cortex of both kidneys in addition to multiple sites of lymphomatous involvement. The patient was not receiving chemotherapy or any nephrotoxic drugs, and no other reasons that may account for renal uptake of gallium could be identified. The final clinical diagnosis was nephrotic syndrome as an unusual paraneoplastic syndrome of Hodgkin's disease. Gallium imaging was able to detect multiple sites of lymphoma and the renal uptake due to the associated nephrotic syndrome.
Department of Radiology, Children's Hospital of Philadelphia, Pennsylvania 19104.
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M
Juweid
C K
CK
Kim
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S
Heyman
D000293:Adolescent; D002951:Citrates; D019343:Citric Acid; D005710:Gallium Radioisotopes; D006689:Hodgkin Disease / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008297:Male; D009404:Nephrotic Syndrome / Q000000981:diagnostic imaging* / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging
D002951:Citrates; D005710:Gallium Radioisotopes; D019343:Citric Acid