Bronchiolitis obliterans associated with rheumatoid arthritis: findings on HRCT and dynamic expiratory CT.
OBJECTIVE
To show the CT findings of bronchiolitis obliterans (BO) associated with rheumatoid arthritis.


METHODS
We used high-resolution CT (HRCT) and dynamic expiratory cine CT to evaluate two patients with rheumatoid arthritis and a clinical diagnosis of BO. Both had pulmonary function tests to correlate with the radiographic findings.


RESULTS
High-resolution CT showed bronchiectasis and mosaic perfusion in both patients. Expiratory CT showed multiple scattered areas of air trapping consistent with small airway obstruction. Imaging findings correlated with pulmonary function tests, which showed severe airway obstruction and inhomogeneous lung ventilation.


CONCLUSIONS
Pulmonary HRCT and dynamic expiratory CT are useful in verifying the clinical diagnosis of BO in patients with rheumatoid arthritis, particularly those too unstable to undergo open lung biopsy.
Department of Radiology, University of California at San Francisco 94143-0628.
S L
SL
Aquino
W R
WR
Webb
J
J
Golden
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000000981:diagnostic imaging*; D001989:Bronchiolitis Obliterans / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D006801:Humans; D014057:Tomography, X-Ray Computed / Q000379:methods*