Chlorpromazine prophylaxis of steroid-induced psychosis.
We report a case of successful prophylactic treatment for psychiatric side effects of megadose glucocorticoid therapy by the administration of chlorpromazine. We review currently used prophylactic treatment strategies and discuss the rationale for adding neuroleptic treatment as an alternative to these strategies.
Hadassah University Hospital, Department of Psychiatry, Jerusalem, Israel.
M
M
Bloch
E
E
Gur
A
A
Shalev
D000328:Adult; D002746:Chlorpromazine / Q000008:administration & dosage* / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects*; D009103:Multiple Sclerosis / Q000188:drug therapy*; D011292:Premedication; D011605:Psychoses, Substance-Induced / Q000517:prevention & control* / Q000523:psychology
D002746:Chlorpromazine; D008775:Methylprednisolone