Teaching active transport at the turn of the twenty-first century: recent discoveries and conceptual changes.
The conceptual advances introduced by recent discoveries in the field of active transport have triggered a transition from a "black box" approach to a "mechanistic" approach. At present, treating this subject in the graduate setting requires consideration of equilibrium and kinetic experimentation, protein chemistry, mutational analysis and molecular structure, with the aim of defining the "transport machine."
Inesi
G
G
Department of Biological Chemistry, University of Maryland School of Medicine, Baltimore 21201.
D000818:Animals; D001693:Biological Transport, Active; D001703:Biophysics / Q000193:education* / Q000639:trends; D000252:Calcium-Transporting ATPases / Q000737:chemistry / Q000378:metabolism; D017136:Ion Transport; D008024:Ligands; D008954:Models, Biological; D008958:Models, Molecular; D012519:Sarcoplasmic Reticulum / Q000378:metabolism; D013379:Substrate Specificity
D008024:Ligands; D000252:Calcium-Transporting ATPases