[Suicidal poisoning with verapamil].
An 18-year-old woman treated in an internal medicine department for heart complaints took clandestinely a high dose of verapamil of unknown origin. She was transferred with block grade III and blood pressure fall to the Department of Cardiology, Province Hospital, where she came with severe cardiogenic+ shock. Resuscitation--electric stimulation (external and then endocavitary), heart massage, artificial ventilation, and the drugs used (orciprenaline, atropine, dopamine, calcium)--was unsuccessful, since despite the bioelectrically effective stimulation myocardial contraction were not achieved, which was probably due to deficit of calcium necessary for activation of contractile elements in muscle fibres. The toxicological investigation demonstrated verapamil (together with its metabolites) in the blood (6 micrograms/ml) and in the liver (42 micrograms/g of tissue).
Szpitala Wojewódzkiego im. J. Sniadeckiego, Białymstoku.
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R
Molenda
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Szrzedziński
D000293:Adolescent; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008099:Liver / Q000737:chemistry; D013405:Suicide; D014700:Verapamil / Q000032:analysis / Q000506:poisoning*
D014700:Verapamil
Samobójcze zatrucie werapamilem.