Tinea capitis: itraconazole in Trichophyton tonsurans infection.
BACKGROUND
Although griseofulvin is considered the standard treatment of tinea capitis, alternatives are being investigated in hopes of identifying more rapid and better cure rates.


OBJECTIVE
Our purpose was to determine the efficacy of itraconazole as therapy for tinea capitis.


METHODS
An open label study was performed on three patients who did not respond to or could not tolerate griseofulvin therapy.


RESULTS
A 30-day course of 100 mg of itraconazole daily resulted in clinical and mycologic cure in all three patients; no side effects were reported.


CONCLUSIONS
Although these results need to be confirmed by larger, controlled trials, it appears that itraconazole offers a viable alternative to griseofulvin for the treatment of children with tinea capitis.
Case Western Reserve University, University Hospitals of Cleveland, OH 44106.
B E
BE
Elewski
D002648:Child; D005260:Female; D006118:Griseofulvin / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D014006:Tinea Capitis / Q000188:drug therapy* / Q000473:pathology
D017964:Itraconazole; D006118:Griseofulvin