[Trials of various regimens for using medamine at different stages in the development of Nippostrongylus brasiliensis].
Experimental invasion of white outbred mice with Nippostrongylus brasiliensis show, that chemotherapeutic effectiveness of medamin is changing in various developmental stages of this helminth. Larva of the fourth phase is most sensitive to medamin; adult worm, especially in the beginning of oviposition, is less sensitive. Chemotherapeutic effect of medamin is increasing with prolongation of therapeutic period, increase of daily doses and degree of its dispersiveness.
Rashid
V M
VM
Astaf'ev
B A
BA
D000818:Animals; D000969:Antinematodal Agents / Q000008:administration & dosage*; D001562:Benzimidazoles / Q000008:administration & dosage*; D002219:Carbamates; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D051379:Mice; D009559:Nippostrongylus / Q000187:drug effects* / Q000254:growth & development; D017206:Strongylida Infections / Q000188:drug therapy / Q000469:parasitology; D013997:Time Factors
D000969:Antinematodal Agents; D001562:Benzimidazoles; D002219:Carbamates; C006698:carbendazim
Ispytaniia razlichnykh skhem primeneniia medamina na raznykh stadiiakh razvitiia Nippostrongylus brasiliensis.