[Examinations of thioamides and their derivatives. X. Salts 1-(o-hydroxy)-alpha-alkylthiobenzylidene) piperidinium, structure, properties and biological activity].
In reactions of 1-(o-hydroxy)thiobenzoylpiperidine with alkyl halides there was obtained 1-(o-hydroxy-alpha-alkylthiobenzylidene)piperidinium bromides and iodides. Structure of obtained compounds have been determined by spectroscopic methods. Products of hydrolysis their and antimitotic and enzymatic activity were investigated too.
Katedra i Zakład Biochemii i Chemii Ogólnej, Akademia Medyczna, Bydgoszcz.
M
M
Santus
M
M
Sołtysiak
S
S
Smoliński
B
B
Stefaniak
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology*; D006868:Hydrolysis; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D051379:Mice; D013057:Spectrum Analysis; D013854:Thioamides / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology*
D000970:Antineoplastic Agents; D013854:Thioamides
Badania w dziedzinie tioamidów i ich pochodnych. X. Sole 1-(o-hydroksy-alpha-alkilotiobenzylideno)piperydyniowe, budowa, właściwości oraz aktywność biologiczna.