[An experimental model of bacterial translocation].
The authors submit an experimental model for bacterial translocation (administering OF-1 mice Zymosan intra-peritoneally at a dose of 1 mg/kg weight). The existence is confirmed of this new mechanism of infection (0% of translocation in control groups, as against 80% in the trial group -p < 0.001). The bacteria in the translocated organs coincide with those present in the fecal flora of the experimental animal. This study is the point of departure for subsequent research to study the physiopathological mechanisms of the phenomenon, which will enable us subsequently to reach better preventive and/or therapeutic decisions.
Lozano Sánchez
F
F
Departamento de Cirugía, Facultad de Medicina, Universidad de Salamanca, España.
García Criado
F J
FJ
García García
I
I
Muñoz de la Espada
B
B
García Sánchez
E
E
Martín Vicente
V
V
Fresnadillo Martínez
M J
MJ
Gómez Alonso
A
A
D000818:Animals; D004195:Disease Models, Animal; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D006094:Gram-Positive Bacteria; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology*; D007422:Intestines / Q000382:microbiology*; D051379:Mice; D011897:Random Allocation
Modelo experimental sobre translocación bacteriana.