Giardia lamblia infections in adult mice.
An adult mouse-Giardia lamblia model was developed and used to study host-parasite interactions, including antigenic variation. The H7/1 clone of isolate GS infected mice consistently and produced infections in 14 mouse strains tested. Infection patterns were mouse strain and Giardia isolate dependent. Antigenic variation occurred in immunocompetent mice but not in mice with severe combined immunodeficiency.
Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, Maryland.
L G
LG
Byrd
J T
JT
Conrad
T E
TE
Nash
D000818:Animals; D000953:Antigens, Protozoan / Q000032:analysis; D005260:Female; D016829:Giardia lamblia / Q000276:immunology*; D005873:Giardiasis / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D016513:Mice, SCID
D000953:Antigens, Protozoan