A case of peroxidase-positive acute leukaemia expressing only T lineage lymphoid markers.
We report the clinical presentation and the morphological, immunophenotypic, cytogenetic and molecular genetic characteristics of a 14 1/2-year-old boy who had French-American-British (FAB) type M1 acute non-lymphocytic (ANLL) leukaemia with a common T-ALL immunological phenotype, with no myeloid associated antigen, either on the membrane or in the cytoplasm. ALL-directed induction therapy induced complete remission.
Laboratoire d'Hématologie et d'Immunologie, Hôpital Intercommunal de Créteil, France.
F
F
Lelong
P
P
Chretien
H
H
Jouault
N
N
Bayani
F
F
Bernaudin
S
S
Lemerle
D000293:Adolescent; D015703:Antigens, CD / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D006801:Humans; D016130:Immunophenotyping; D015470:Leukemia, Myeloid, Acute / Q000145:classification / Q000201:enzymology / Q000276:immunology* / Q000473:pathology; D008297:Male; D009195:Peroxidase / Q000032:analysis*; D013601:T-Lymphocytes / Q000276:immunology*
D015703:Antigens, CD; D000951:Antigens, Neoplasm; D009195:Peroxidase