Surgical treatment of pulmonary metastases from soft tissue sarcomas: a retrospective study in The Netherlands.
Sixty-seven of 87 patients with soft tissue sarcoma underwent complete resection of the metastases in the lung. In this retrospective study, follow-up was for a median of 24 months. The 5-year overall, crude and disease-free survival was 38%, 45%, and 41%, respectively. Twenty-seven (40%) patients developed a recurrence in the lung. Of the six prognostic variables, the only factor significantly related to disease-free survival was grade. It is concluded that surgery for lung metastases of soft tissue sarcoma should be considered as standard therapy when preoperative evaluation predicts a complete resection. By adding chemotherapy to surgery, an improvement of prognosis probably can be achieved.
Dr. Daniel den Hoed Cancer Center, Rotterdam, Netherlands.
A N
AN
van Geel
F
F
van Coevorden
J D
JD
Blankensteijn
H J
HJ
Hoekstra
B
B
Schuurman
E D
ED
Bruggink
C W
CW
Taat
E B
EB
Theunissen
D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D009426:Netherlands / Q000453:epidemiology; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D012509:Sarcoma / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D016019:Survival Analysis; D015996:Survival Rate; D013997:Time Factors