Three cases of acute hepatitis E virus infection imported into Norway.
We report 3 cases of acute hepatitis E virus (HEV) infection imported from Asia. All 3 patients had fever and upper abdominal discomfort preceding jaundice which lasted 2-3 weeks with maximum bilirubin levels of 141-254 mmol/l. The ALT values peaked between 1,347 and 3,690 U/l. Both values normalized within 1-2 months. During the acute phase of the disease, all patients had high levels of IgG and IgM antibodies against HEV (anti-HEV) recombinant and synthetic peptides. The duration of the anti-HEV IgM was about 1-2 months.
Skaug
K
K
Department of Microbiology, Ullevål University Hospital, Oslo, Norway.
Hagen
I J
IJ
von der Lippe
B
B
D000208:Acute Disease; D000328:Adult; D001208:Asia; D001663:Bilirubin / Q000097:blood; D006508:Hepatitis Antibodies / Q000097:blood; D016751:Hepatitis E / Q000453:epidemiology*; D016752:Hepatitis E virus / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D002052:Myanmar / Q000208:ethnology; D009664:Norway / Q000453:epidemiology; D013188:Sri Lanka / Q000208:ethnology; D014195:Travel
D006508:Hepatitis Antibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D001663:Bilirubin