Preparation and properties of buserelin suspensions.
Obtaining and some properties of suspensions with buserelin-there were obtained buserelin suspensions with zinc ions with pH 7.2-7.5 and hormone: zinc molar ratio from 1:2.5 to 1:500. The obtained buserelin suspensions show moderated hormone release in vitro and prolonged action in vivo. The pulsating buserelin release from suspensions has been found in vitro and in vivo.
Ryszka
F
F
Department of Applied Pharmacy and Drug Technology Medical Silesian Academy, Sosnowiec, Poland.
Dolińska
B
B
Szulc
B
B
Zientarska
G
G
D000818:Animals; D002064:Buserelin / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D007273:Injections, Intramuscular; D013535:Suspensions; D013552:Swine
D013535:Suspensions; D002064:Buserelin