Anti-bacillus substance in the marine sponge, Hyatella species, produced by an associated Vibrio species bacterium.
The bacterial isolate, M22-1, belonging to the genus Vibrio was obtained from an homogenate of the sponge, Hyatella sp. The bacterium was cultured in marine agar and was found to produce an anti-Bacillus compound. The substance was chemically identified as a peptide antibiotic, an andrimid. The same substance was found in the sponge extract, suggesting that the active component was synthesized by the associated microorganism.
Department of Applied Biochemistry, Hiroshima University, Japan.
J M
JM
Oclarit
H
H
Okada
S
S
Ohta
K
K
Kaminura
Y
Y
Yamaoka
T
T
Iizuka
S
S
Miyashiro
S
S
Ikegami
D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification*; D011090:Polyenes / Q000737:chemistry / Q000302:isolation & purification; D011161:Porifera / Q000382:microbiology*; D011758:Pyrroles / Q000737:chemistry / Q000302:isolation & purification; D013559:Symbiosis; D014733:Vibrio / Q000302:isolation & purification / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D011090:Polyenes; D011758:Pyrroles; C088069:andrimid