Studies on the inheritance of repellent tolerances in Aedes aegypti.
Two laboratory strains and 6 inbred strains of Aedes aegypti were tested against deet, ethyl hexanediol, dimethyl phthalate, and Indalone. Reciprocal crosses and backcrosses of 2 inbred strains were tested against deet only. Results obtained were compatible with a quantitative genetic model in which the effects of the factors involved were multiplicative. Certain inbred strains differed significantly from cognate laboratory and/or inbred strains in tolerance to one or more test materials. Heritability in the broad sense (H2) was estimated at 0.05 for deet, 0.22 for ethyl hexanediol, 0.48 for dimethyl phthalate, and 0.51 for Indalone. Partial dominance was observed in the inheritance of tolerance to deet.
Letterman Army Institute of Research, Presidio of San Francisco, CA 94129-6800.
L C
LC
Rutledge
R K
RK
Gupta
G N
GN
Piper
C A
CA
Lowe
D000330:Aedes / Q000235:genetics*; D000818:Animals; D002633:Chemotaxis / Q000235:genetics; D003433:Crosses, Genetic; D003671:DEET; D006018:Glycols; D007178:Inbreeding; D007302:Insect Repellents; D007305:Insecticide Resistance / Q000235:genetics; D010795:Phthalic Acids; D011714:Pyrans; D012044:Regression Analysis; D013045:Species Specificity
D006018:Glycols; D007302:Insect Repellents; D010795:Phthalic Acids; D011714:Pyrans; C024629:dimethyl phthalate; D003671:DEET; C052596:butopyronoxyl; C004917:ethohexadiol