The blue-green autofluorescence of the human ocular lens after the wear of PMMA contact lenses.
The green ocular lens autofluorescence was determined in 30 Poly Methyl Meth Acrylate (PMMA) contact lens wearing volunteers and compared to that of 21 healthy non-contact lens wearing controls to determine whether a contact lens, reducing UV-A intensity reaching the eye, might protect the ocular lens against cataract formation. Increased autofluorescence was considered an indicator of increased probability for cataract formation. A multiple regression procedure revealed a significant yearly increase of autofluorescence with age (p < 0.01) which did not differ significantly (p > 0.86) from that in the controls. The regression procedure also revealed a decrease of the autofluorescence as a function of contact lens wear, but this decrease was not significant (p = 0.3). The order of magnitude of the decrease (-25%) corresponded to that of the calculated decrease in UV-A intensity at the ocular lens (-39%). This study could not support the thesis that cataract formation can be prevented by wearing PMMA contact lenses.
Department of Ophthalmology, University Hospital, Leiden, The Netherlands.
E P
EP
Boets
J H
JH
Kok
J A
JA
van Best
D000328:Adult; D000375:Aging / Q000502:physiology; D002386:Cataract / Q000517:prevention & control; D003261:Contact Lenses; D005260:Female; D005453:Fluorescence; D015590:Fluorophotometry; D006801:Humans; D007908:Lens, Crystalline / Q000737:chemistry* / Q000528:radiation effects; D008297:Male; D020366:Methylmethacrylate; D008768:Methylmethacrylates; D008875:Middle Aged; D011832:Radiation Injuries / Q000517:prevention & control; D014466:Ultraviolet Rays
D008768:Methylmethacrylates; D020366:Methylmethacrylate