[Investigation of antigen reaction of placental blood vessel in pregnancy-induced hypertension].
The antigen reactions of factor VIII (FVIII), IgA, IgG, IgM and C'3 of the endothelium and basilar membrane of placental vessels in 31 cases with pregnancy-induced hypertension (PIH) using immunocytochemical technique were studied. The results showed a decrease or absence of FVIII in the endothelium of the blood vessel. The antigens of IgA, IgG, IgM and C'3 were limited within the endothelium and basilar membrane of the placental blood vessels and overreacted. The immunological mechanism in PIH was discussed.
PLA Kunming General Hospital.
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Yi
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Luo
D000328:Adult; D001485:Basement Membrane / Q000276:immunology; D002196:Capillaries / Q000473:pathology; D003176:Complement C3 / Q000276:immunology; D004730:Endothelium, Vascular / Q000276:immunology*; D005169:Factor VIII / Q000276:immunology; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D010920:Placenta / Q000098:blood supply*; D011225:Pre-Eclampsia / Q000276:immunology*; D011247:Pregnancy
D003176:Complement C3; D007136:Immunoglobulins; D005169:Factor VIII