[Panniculitis associated with severe alpha 1-antitrypsin deficiency].
Genetically determined deficiency of alpha-1-antitrypsin, the primary serum protease inhibitor, can result in pulmonary emphysema or liver cirrhosis, and panniculitis may be an early symptom. A case of recurring panniculitis in a 29 year-old woman is described, which led to the diagnosis of severe alpha-1-antitrypsin deficiency (Pi ZZ). Serum alpha-1-antitrypsin levels should be measured in patients presenting with panniculitis.
Odense Universitetshospital, dermatologisk afdeling.
J B
JB
Traulsen
D000328:Adult; D005260:Female; D006801:Humans; D015434:Panniculitis / Q000150:complications* / Q000201:enzymology / Q000235:genetics; D010641:Phenotype; D012008:Recurrence; D000515:alpha 1-Antitrypsin / Q000235:genetics; D019896:alpha 1-Antitrypsin Deficiency
D000515:alpha 1-Antitrypsin
Panniculitis associeret med svaer alfa-1-antitrypsinmangel.