[The effect of T cells in pathogenesis of glomerular nephritis].
T lymphocytes were infused to congenital athymic nude mice to reconstitute its cellular immunological function. Success was then achieved in inducing crescentic glomerular nephritis in the nude mice. No pathological changes were observed in the control group of nude mice which did not receive T lymphocyte infusion. Results of this study suggest that T lymphocytes play an important role in the pathogenesis of crescentic glomerular nephritis.
Department of Pathology, Beijing Medical University.
A P
AP
Du
W Z
WZ
Zou
D000818:Animals; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D007678:Kidney Glomerulus / Q000648:ultrastructure; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D013601:T-Lymphocytes / Q000276:immunology*