Synthesis and characterization of [125I]-N-(N-benzylpiperidin-4-yl)-4- iodobenzamide, a new sigma receptor radiopharmaceutical: high-affinity binding to MCF-7 breast tumor cells.
John
C S
CS
Department of Radiology, George Washington University Medical Center, Washington, D.C. 20037.
Vilner
B J
BJ
Bowen
W D
WD
D000818:Animals; D001549:Benzamides / Q000138:chemical synthesis* / Q000378:metabolism; D001665:Binding Sites; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D006168:Guinea Pigs; D006801:Humans; D007457:Iodine Radioisotopes; D010880:Piperidines / Q000138:chemical synthesis* / Q000378:metabolism; D011877:Radionuclide Imaging; D017480:Receptors, sigma / Q000378:metabolism*; D014407:Tumor Cells, Cultured
D001549:Benzamides; D007457:Iodine Radioisotopes; D010880:Piperidines; D017480:Receptors, sigma; C088152:N-(N-benzylpiperidin-4-yl)-4-iodobenzamide