[Comprehensive evaluation of the effectiveness of antibiotics in experimental typhus infection].
The informative indices of antibiotic efficacy in the treatment of typhus were determined in experiments on guinea pigs and used for the design of an integral index of a drug prophylactic activity against Rickettsia prowazekii. A procedure for a comprehensive estimation of an antibiotic prophylactic efficacy in experimental typhus by the whole complex of clinical, immunological and rickettsiological properties is described.
T M
TM
Plekhanova
V N
VN
Lazarenko
V M
VM
Ruchko
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006168:Guinea Pigs; D012283:Rickettsia prowazekii / Q000187:drug effects* / Q000254:growth & development; D014438:Typhus, Epidemic Louse-Borne / Q000382:microbiology / Q000517:prevention & control*
D000900:Anti-Bacterial Agents
Kompleksnaia otsenka éffektivnosti antibiotikov pri éksperimental'noĭ sypnotifoznoĭ infektsii.