[Neutrophilia in the bronchoalveolar lavage of patients with AIDS and Pneumocystis carinii pneumonia. Reflections on its prognostic value in the Spanish setting].
The prognostic value of neutrophilia (> 5%) in bronchoalveolar lavage (BAL) in our context is studied in 21 patients with AIDS and Pneumocystis carinii pneumonia. Neutrophilia does not seem to be a good prognostic indicator in our context. We have found this condition, with a mean of 6 +/- 4%, in only 33% of our sample. The sensitivity of this parameter with respect to risk of death was very low (25%), while specificity was moderate (65%). In contrast with what has been reported in studies done with Anglo-Saxon populations, neutrophilia in BAL is probably of little prognostic use in our context. This may be due to various factors, among them the type of population (most being intravenous drug users) and the therapeutic protocol (early empirical treatment).
Servicio de Neumología, Hospital del Mar, Barcelona.
J
J
Sauleda
J
J
Gea
X
X
Aran
E
E
Gimferrer
M
M
Conangla
J M
JM
Broquetas
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000401:mortality; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000401:mortality; D000328:Adult; D015415:Biomarkers; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology* / Q000382:microbiology; D001999:Bronchoscopy; D005260:Female; D015497:HIV-1; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D009504:Neutrophils / Q000166:cytology*; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis* / Q000401:mortality; D011379:Prognosis; D012680:Sensitivity and Specificity; D013030:Spain / Q000453:epidemiology; D015819:Substance Abuse, Intravenous / Q000150:complications
D015415:Biomarkers
Neutrofilia en el lavado broncoalveolar de pacientes con SIDA y neumonía por Pneumocystis carinii. Consideraciones sobre su valor pronóstico en nuestro medio.