The discovery of the relationship between mast cells, histamine and IgE.
Two years after graduating from medical school, Ivan Mota decided to spend a year doing postgraduate training. Little did he realise that he was embarking on a course that would see him lay the foundations for modern research into allergy and anaphylaxis. Here, he recounts his own tale.
Immunopathology Laboratory, Institute Butantan, São Paulo, Brazil.
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D000707:Anaphylaxis / Q000266:history*; D000818:Animals; D001938:Brazil; D006632:Histamine / Q000266:history* / Q000502:physiology; D049673:History, 20th Century; D007073:Immunoglobulin E / Q000266:history* / Q000502:physiology; D008407:Mast Cells / Q000502:physiology
D007073:Immunoglobulin E; D006632:Histamine