[Rheumatoid arthritis of the hand. The initial results with 31-phosphorus MR spectroscopy].
The aim of this study was to demonstrate metabolic changes in the small joints of the hand due to rheumatoid arthritis by means of 31-phosphorus spectroscopy. Suitable measurements were developed and 11 normals and 12 patients were then examined during the course of treatment. Relative concentration of low energy phosphorus metabolites was increased in arthritic joints. The phospholipid quotient (phosphomonoester/phosphodiester) and the relationship of inorganic phosphate and beta-nucleoside triphosphate were significant factors during the course of individual treatments.
Abteilung für Radiologische Diagnostik und Nuklearmedizin, Klinikum Steglitz, FU, Berlin.
F
F
Wacker
A
A
Schilling
J
J
Braun
M
M
Bollow
H
H
König
K J
KJ
Wolf
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000378:metabolism*; D004008:Diclofenac / Q000627:therapeutic use; D005260:Female; D006225:Hand; D006226:Hand Deformities / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D007596:Joints / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000378:metabolism; D013997:Time Factors
D004008:Diclofenac; D010758:Phosphorus
Rheumatoide Arthritis der Hand. Erste Ergebnisse mit der 31Phosphor-MR-Spektroskopie.