Orbital floor steroid injections in the treatment of uveitis.
Orbital floor steroid injections, like other posterior periocular injections, are advocated as a means of avoiding systemic immunosuppression in the management of uveitis in which there is significant posterior segment inflammation, but there are no published studies on their efficacy. The results of 54 orbital floor steroid injections to 33 eyes with uveitis were analysed. A positive response with an average duration of effect of 9 weeks was obtained after 48% of injections. These results compare favourably with the results of systemic immunosuppression in patients with comparable patterns of uveitis, thus establishing the efficacy of orbital floor steroid injections and their potential value when systemic immunosuppression needs to be avoided.
Uveitis Clinic, Moorfields Eye Hospital, London, UK.
P
P
Riordan-Eva
S
S
Lightman
D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000031:analogs & derivatives; D000077555:Methylprednisolone Acetate; D008875:Middle Aged; D009915:Orbit; D015868:Pars Planitis / Q000188:drug therapy; D013997:Time Factors; D016896:Treatment Outcome; D014221:Triamcinolone / Q000008:administration & dosage; D014605:Uveitis / Q000188:drug therapy*; D014792:Visual Acuity
D000893:Anti-Inflammatory Agents; D014221:Triamcinolone; D000077555:Methylprednisolone Acetate; D008775:Methylprednisolone