Clinical and radiographic findings in disseminated tuberculosis of the brain.
We report clinical and radiographic findings in a patient with disseminated tuberculosis (TB) of the brain. A Burmese man developed a left hemiparesis and mild cognitive difficulty 1 month into therapy for miliary TB. A head MRI showed numerous (> 100) contrast-enhancing supratentorial and infratentorial lesions. Following 9 months of treatment with isoniazid, ethambutol, rifampin, and pyrazinamide, most lesions resolved; however, one cortical tuberculoma enlarged significantly. The patient was continued on isoniazid and rifampin, with radiographic resolution of the tuberculoma 4 months later.
Department of Neurology, University of California, San Francisco 94143-0724.
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D000328:Adult; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014391:Tuberculosis, Miliary / Q000000981:diagnostic imaging* / Q000473:pathology*