Giant-cell fibroblastoma with pigmented dermatofibrosarcoma protuberans component.
A unique case of giant-cell fibroblastoma that contained a pigmented dermatofibrosarcoma component (Bednár tumor) is described. The melanin pigmented dendritic cells found in the dermatofibrosarcoma component were round or spindle-shaped and had bipolar extensions. They were S-100 protein positive. Our case indicates the close histogenetic relationship between giant-cell fibroblastoma and dermatofibrosarcoma protuberans. The occurrence of the pigmented melanin-laden dendritic cells in our tumor further substantiates the theory that Bednár tumor is a pigmented variant of dermatofibrosarcoma protuberans.
Department of Pathology, General Hospital, Trencín, Slovakía.
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Zámecník
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Michal
D000328:Adult; D018223:Dermatofibrosarcoma / Q000378:metabolism / Q000473:pathology*; D005350:Fibroma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012782:Shoulder; D012983:Soft Tissue Neoplasms / Q000378:metabolism / Q000473:pathology*; D014746:Vimentin / Q000378:metabolism
D014746:Vimentin