[Biological age, adrenoreception and lipid peroxidation in patients with ischemic heart disease].
The article deals with electro-kinetic potential of cellular nucleus considered as an indicator of unspecific reactivity and presents some data on molecular and cellular mechanisms of adreno- and muscarino-receptive interactions, such as adrenalin, noradrenaline and DOPA blood levels, lipid peroxidation, erythrocyte resistance to peroxidation. The attempt is made to comprehend directions and trends of aforementioned processes in patients with stable and unstable stenocardia as well as in myocardial infarction with regard to sex and influence of central M-cholinoblockader amizyl. The drug provides adaptive effect, corrects affected adreno-reception, protects biomembranes from lesion, promotes their "fluidity" and reduces rigidity.
Shushliapin
O I
OI
Kononenko
L G
LG
Bakhova
L K
LK
Koroza
S A
SA
Shelest
A N
AN
D000328:Adult; D000368:Aged; D000375:Aging / Q000097:blood / Q000187:drug effects / Q000502:physiology*; D001535:Benactyzine / Q000627:therapeutic use; D002610:Cheek; D004594:Electrophysiology; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000502:physiology; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000166:cytology / Q000187:drug effects / Q000502:physiology; D017202:Myocardial Ischemia / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000502:physiology*
D011941:Receptors, Adrenergic; D001535:Benactyzine
Biologicheskiĭ vozrast, adrenoretseptsiia i perekisnoe okislenie lipidov u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.