Glucosidase inhibition assay as prescreen for natural products.
A glucosidase inhibition assay has been used to evaluate extracts from higher plants. An enzyme inhibition of fifty percent or more correlated with the observed cytotoxicity of the extracts.
Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico, San Juan 00936-5067.
M D
MD
Antoun
Y R
YR
Ríos
N T
NT
Mendoza
G
G
Proctor
D000998:Antiviral Agents / Q000494:pharmacology; D016923:Cell Death / Q000187:drug effects; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D006678:HIV / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology* / Q000633:toxicity; D011647:Puerto Rico; D001617:beta-Glucosidase / Q000037:antagonists & inhibitors*
D000998:Antiviral Agents; D010936:Plant Extracts; D001617:beta-Glucosidase