[The detection of antibodies to the hepatitis C virus and to HBsAg in donors with viral hepatitis and cancerous diseases in the Republic of Moldova].
Large-scale and uneven distribution of hepatitis C and B (HC and HB) among free blood donors of different regions of the Moldova Republic was established. The rate of detection of anti-HCV (South 6.2%, North 3.6%) correlated with that of HBsAg detection (south 12.5%, north 4.5%). A great role of HCV in the etiology of acute (among them posttransfusion) hepatitis and chronic hepatitis was demonstrated. A significant frequency of detection of anti-HCV (15%) in children treated in oncohematology wards and receiving multiple hemotransfusions as well as the detected cases of acute posttransfusion HC attest to active realization of this virus transmission in the transfusions of blood and/or its components. The necessity of urgent introduction into the Blood Transfusion Service of the republic of the examination of blood donors for HBsAg, alongside with their examination for the presence of anti-HCV and vaccination prophylaxis of HB in high risk groups is substantiated.
S S
SS
Kostritsa
S N
SN
Kuzin
P A
PA
Khukhlovich
I V
IV
Shakhgil'dian
N V
NV
Doroshenko
V M
VM
Blinov
V N
VN
Loparen
L L
LL
Sukhanova
V A
VA
Gol'tsov
Zh A
ZhA
Drobeniuk
D000328:Adult; D001782:Blood Donors / Q000706:statistics & numerical data; D002648:Child; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006509:Hepatitis B / Q000453:epidemiology / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006526:Hepatitis C / Q000453:epidemiology / Q000276:immunology*; D006521:Hepatitis, Chronic / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D015994:Incidence; D008966:Moldova / Q000453:epidemiology; D009369:Neoplasms / Q000453:epidemiology / Q000276:immunology*; D016036:Seroepidemiologic Studies
D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens
Vyiavlenie antitel k virusu gepatita C i HBsAg u donorov, bol'nykh virusnymi gepatitami i onkologicheskimi zabolevaniiami, v Respublike Moldova.