[The effect of hyperbaric oxygenation on the microcirculation, oxygen budget and acid-base equilibrium in patients with diabetic angiopathy of the lower extremities].
These effects were studied in 52 patients with degrees III-IV diabetic angiopathies of the lower limbs. Microcirculation parameters were found changed in this patient population, this leading to disorders of the oxygen budget and development of metabolic acidosis. Development of destructive changes in the limb evidences failure of the compensatory adaptive mechanisms of microcirculation. Addition of hyperbaric oxygenation to multiple-modality treatment of patients with diabetic angiopathies was conducive to improvement of the blood rheology, of tissue saturation with oxygen, and to essential reduction of metabolic acidosis. The detected microcirculation disorders necessitate addition to the therapeutic complex of the drugs improving the biophysical characteristics of the blood.
Gonchar'
M G
MG
Vavrik
Zh M
ZhM
Del'tsova
E I
EI
Zelenetskiĭ
R G
RG
D000136:Acid-Base Equilibrium; D000368:Aged; D000672:Amputation Stumps / Q000098:blood supply; D000704:Analysis of Variance; D002196:Capillaries / Q000648:ultrastructure; D003131:Combined Modality Therapy; D003925:Diabetic Angiopathies / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000706:statistics & numerical data; D007866:Leg / Q000098:blood supply*; D008297:Male; D008833:Microcirculation / Q000503:physiopathology; D008875:Middle Aged; D010101:Oxygen Consumption
Vliianie giperbaricheskoĭ oksigenatsii na mikrotsirkuliatsiiu, kislorodnyĭ biudzhet i kislotno-shchelochnoe ravnovesie u bol'nykh s diabeticheskoĭ angiopatieĭ nizhnikh konechnosteĭ.