[Gougerot-Sjögren syndrome. Central neurological involvement with recurrent development].
A 64-year-old woman was repeatedly hospitalized for various recurrent clinical signs of central nervous system involvement. The diagnosis of primary Sjögren's syndrome was established 3 years 6 months after the onset of the disease. Sicca symptoms, as well as inflammatory biological abnormalities were absent. Moreover, both lacrymal and salivary gland secretions were affected. A high level of antinuclear antibodies to SSA and SSB was associated with inflammatory lesions in minor salivary glands biopsy samples consistent with the diagnosis of Sjögren's syndrome.
Clinique Neurologique, Hôpital Bretonneau, Tours.
P
P
Ménage
B
B
de Toffol
D
D
Degenne
D
D
Saudeau
P
P
Bardos
A
A
Autret
D000974:Antibodies, Antinuclear / Q000032:analysis; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012008:Recurrence; D012859:Sjogren's Syndrome / Q000150:complications*
D000974:Antibodies, Antinuclear
Syndrome de Gougerot-Sjögren primitif. Atteinte neurologique centrale évoluant par poussées.