[Cigarette smoking and circulatory crisis in tissue transfer].
Circulatory crisis occurred in 2 cases of toe-to-hand transfer and 1 case of musculocutaneous free flap after smoking. Two of them failed and 1 survived after exceeding anti-spasm and anti-thrombosis treatment. Experimental studies showed harmful influences of cigarette smoking on endothelial healing process at the vascular anastomosis site, which was covered by endothelial cells in 16%-32% and platelet in 8%-10% of the smoking group 5-10 days after operation, but in 75%-100% and 0% of the normal group. The mechanism and characteristics of circulatory crisis caused by cigarette smoking are discussed.
Institute of Hand Surgery, Huashan Hospital, Shanghai Medical University.
Y D
YD
Gu
L Y
LY
Zhang
C
C
Yu
D000328:Adult; D000714:Anastomosis, Surgical; D000818:Animals; D001917:Brachial Plexus / Q000293:injuries; D005260:Female; D006085:Graft Survival; D006801:Humans; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012907:Smoking / Q000009:adverse effects*; D013524:Surgical Flaps / Q000379:methods; D013933:Thumb / Q000293:injuries* / Q000601:surgery; D014034:Toes / Q000637:transplantation*