A case of inverted papilloma of the ureter: is the DNA ploidy pattern associated with occurrence of transitional cell carcinoma of the bladder?
We describe herein a case of inverted papilloma of the ureter, in which transitional cell carcinoma of the bladder developed twenty-three months after nephroureterectomy. Flow cytometric analysis of formalin-fixed and paraffin-embedded archival material of the inverted papilloma revealed DNA aneuploidy pattern and relatively high percentage of S phase. Retrospectively, DNA measurement thus provided the predictive value regarding biological activity and the clinical behaviour of the present case.
Department of Urology, School of Medicine, Kanazawa University, Japan.
K
K
Kunimi
T
T
Uchibayashi
M
M
Egawa
D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000473:pathology; D004273:DNA, Neoplasm / Q000235:genetics; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology; D018308:Papilloma, Inverted / Q000235:genetics* / Q000473:pathology; D011003:Ploidies; D014516:Ureteral Neoplasms / Q000235:genetics* / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000473:pathology
D004273:DNA, Neoplasm