A neuromagnetic study of the functional organization of the sensorimotor cortex.
Movement-related neuromagnetic fields from eight healthy human subjects were investigated in a Bereitschaftspotential paradigm. The three conditions studied were right-sided mouth, index finger and foot movement. The neuromagnetic field patterns corresponding to the motor field and the movement-evoked field I were analysed using a moving dipole model. For both components a somatotopic organization was found: the estimated dipole locations for the mouth were more lateral and those for the foot more medial than the estimated dipole positions for the index finger movement. With regard to possible clinical applications, e.g. non-invasive mapping of the sensorimotor cortex and studies of plasticity of the motor function, the present results suggest that the investigation of movement-evoked field I for the index finger condition is most likely to yield further results.
Institute of Biomedical Engineering, University of Ulm, Germany.
R
R
Kristeva-Feige
H
H
Walter
B
B
Lütkenhöner
S
S
Hampson
B
B
Ross
U
U
Knorr
H
H
Steinmetz
D
D
Cheyne
D000328:Adult; D001931:Brain Mapping; D004576:Electromyography; D005071:Evoked Potentials; D005260:Female; D005385:Fingers / Q000294:innervation; D005528:Foot / Q000294:innervation; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D008959:Models, Neurological; D009043:Motor Activity; D009055:Mouth / Q000294:innervation; D009068:Movement; D013003:Somatosensory Cortex / Q000033:anatomy & histology / Q000502:physiology*