PF1018, a novel insecticidal compound produced by Humicola sp.
A new insecticidal compound PF1018 was isolated from the culture broth of Humicola sp. It exhibited insecticidal activity against a wide range of critical pest species. The structure of PF1018 was determined to be (7aS)-2-((2E)-1-hydroxy-3-((1S,3aR,4R,5R,7aR)-3a,4,5,7 a-tetrahydro-1,3,5,7- tetramethyl-5,1-((3S)-(Z)-2,3-dimethylpropeno)-1H-inden-4-yl )-2- propenylidene)pyrrolizidine-1,3-dione, by NMR spectral analyses coupled with X-ray crystallographic analysis and chemical degradation study.
Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd., Yokohama, Japan.
S
S
Gomi
K
K
Imamura
T
T
Yaguchi
Y
Y
Kodama
N
N
Minowa
M
M
Koyama
D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D005285:Fermentation; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D003904:Mitosporic Fungi / Q000737:chemistry* / Q000145:classification; D015394:Molecular Structure; D011763:Pyrrolizidine Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D007306:Insecticides; D011763:Pyrrolizidine Alkaloids; C088533:PF 1018