Expression of lactic dehydrogenase isoenzymes in rabbit muscle during development.
1. Rabbit cDNA probes for H and M lactic dehydrogenase subunits were used to monitor mRNA levels in different muscle types during growth. 2. At the same time, lactic dehydrogenase activity and relative quantities of H and M protein subunits were measured. 3. The main results are that mRNA abundance depends on muscle type and age, and mRNA abundance is not correlated with enzymatic activity.
Marieze
V L
VL
Laboratoire de Biochimie, Université Blaise Pascal-Clermont II, Aubiere, France.
Briand
M
M
Badaoui
S
S
Dadet
M H
MH
Briand
Y
Y
D000367:Age Factors; D000818:Animals; D018076:DNA, Complementary / Q000235:genetics; D015870:Gene Expression; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000235:genetics / Q000378:metabolism*; D024510:Muscle Development; D009132:Muscles / Q000201:enzymology*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D011817:Rabbits
D018076:DNA, Complementary; D007527:Isoenzymes; D012333:RNA, Messenger; D007770:L-Lactate Dehydrogenase