[The role of biotransformation in assessing the toxicological risk from pesticides].
Pesticides are an extremely heterogeneous group of chemical compound with varying toxicity. The biotransformation and degradation mechanisms are essential factors in the regulation of their toxic effects and of their persistence in the environment and biological tissues. Knowledge of metabolism and measurement of metabolites are fundamental to evaluate the risk from residues in food and water and to assess the toxicological risk for subjects occupationally exposed to pesticides.
Maroni
M
M
Istituto di Medicina del Lavoro, Università degli Studi di Milano.
Bersani
M
M
D001280:Atrazine / Q000493:pharmacokinetics / Q000633:toxicity; D001711:Biotransformation; D004785:Environmental Pollutants / Q000493:pharmacokinetics / Q000633:toxicity; D006801:Humans; D016273:Occupational Exposure / Q000009:adverse effects / Q000706:statistics & numerical data; D010575:Pesticides / Q000493:pharmacokinetics* / Q000633:toxicity*; D012307:Risk Factors
D004785:Environmental Pollutants; D010575:Pesticides; D001280:Atrazine
Ruolo della biotrasformazione nella valutazione del rischio tossicologico da pesticidi.