[Use of an "immunologic compass" for diagnosis of immune disorders in clean-up crew members after the accident at the Chernobyl nuclear power plant].
A total of 389 patients with cerebrovascular diseases who participated in liquidation of the Chernobyl power plant accident consequences were examined using rosette formation test and the cytotoxic method with monoclonal antibodies (MCAB). The predominant type of immunologic abnormalities found in 79.1% of patients was a marked reduction of CD4+ cell (T-helpers/inductors) count and a moderate reduction of CD8+ (T-suppressor/keller) count, this resulting in reduction of the CD4/CD8 coefficient. In 11.3% of the examinees CD(4+)-lymphocyte count was reduced and CD8+ count was within the normal range, in 6.2% both CD4+ and CD8+ counts were reduced, and in 3.4% CD4+ count was reduced and CD8+ moderately elevated. Results of theophylline test did not coincide with those of CD4+ and CD8+ measurements in 44.2% of cases.
Frolov
V M
VM
Peresadin
N A
NA
Kazakova
S E
SE
Safonova
E F
EF
Korobka
Iu N
IuN
Petrunia
A M
AM
D000059:Accidents; D000328:Adult; D005260:Female; D006801:Humans; D007154:Immune System Diseases / Q000209:etiology*; D008297:Male; D009688:Nuclear Reactors; D009784:Occupational Diseases / Q000209:etiology*; D016273:Occupational Exposure; D011848:Radioactive Pollutants / Q000009:adverse effects*; D014455:Ukraine
D011848:Radioactive Pollutants
Ispol'zovanie "immunologicheskogo kompasa" dlia diagnostiki immunnykh narusheniĭ u uchastnikov likvidatsii posledstviĭ avarii na Chernobyl'skoĭ AES.