[Studies on the hypoglycemic effect of Rhodiola sachalinensis A. Bor. polysaccharides].
Rhodiola sachalinensis polysaccharides (RSP) isolated from the root of Rhodiola sachalinensis was demonstrated to decrease the levels of blood sugar, liver glycogen and total blood lipid when injected peritoneally to mice at 50, 100 and 200 mg/kg once or for 7 successive days. In addition, RSP was found to decrease blood sugar and total blood lipid in various experimental hyperglycemias induced by injection of adrenaline, glucose and alloxan in mice. RSP exhibit inhibiting effect on the glycogen enhancement induced by glucose as well as strenghtening effect on the glycogen decomposition induced by adrenaline and alloxan.
Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun.
X J
XJ
Cheng
L
L
Di
Y
Y
Wu
Q C
QC
Zhao
G Z
GZ
Du
Y Q
YQ
Liu
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008055:Lipids / Q000097:blood; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D051379:Mice; D011134:Polysaccharides / Q000494:pharmacology*
D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents; D008055:Lipids; D008112:Liver Glycogen; D011134:Polysaccharides