Prolonged in vivo administration of cyclosporine causes enteric smooth muscle hyperplasia in normal rat intestine and small bowel grafts.
Heeckt
P F
PF
Department of Surgery, University of Pittsburgh, Pennsylvania 15261.
Halfter
W M
WM
Lee
K K
KK
Schraut
W H
WH
Bauer
A J
AJ
D000818:Animals; D002217:Carbachol / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D016572:Cyclosporine / Q000633:toxicity*; D006965:Hyperplasia; D007421:Intestine, Small / Q000473:pathology* / Q000502:physiology / Q000637:transplantation*; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000473:pathology* / Q000502:physiology / Q000637:transplantation*; D051381:Rats; D011912:Rats, Inbred ACI; D011917:Rats, Inbred Lew; D013997:Time Factors; D014184:Transplantation, Homologous; D014185:Transplantation, Isogeneic
D016572:Cyclosporine; D002217:Carbachol