Risk-factors for Parkinson's disease: case-control study in the province of Cáceres, Spain.
This case-control study, performed in a mixed rural and urban province, of 74 patients with Parkinson's disease (PD) and 148 unselected age and sex-matched controls, attempted to look possible risk factors for PD. Rural living, well-water drinking, positive family history for PD and postural tremor, were associated to an increased risk for PD, with results regarding exposure to pesticides near to statistical significance. Alcohol-drinking habit in males were associated to a decreased risk for PD, with results regarding cigarette-smoking habit in males near to statistical significance. We did not find association between the risk for PD and the following variables: 1) exposure to industrial toxins; 2) agricultural work; 3) cranial trauma; 4) previous common illnesses including some infections, arterial hypertension, diabetes mellitus, coronary heart disease and thyroid disease; 5) coffee and tea drinking habits.
Department of Neurology, Hospital Virgen del Puerto, Plasencia, Cáceres, Spain.
A
A
Morano
F J
FJ
Jiménez-Jiménez
J A
JA
Molina
M A
MA
Antolín
D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000453:epidemiology* / Q000209:etiology*; D010575:Pesticides / Q000633:toxicity; D012307:Risk Factors; D012424:Rural Population; D011795:Surveys and Questionnaires
D010575:Pesticides