Worm burden and mucosal mast cell response in DA and F344/N rat strains infected with Hymenolepis diminuta.
After oral administration of 1 or 5 cysticercoids of Hymenolepis diminuta, 5-week-old DA male rats showed significant mastocytosis. In F344/N rats, however, neither mastocytosis nor worm loss occurred during a 6 week infection. With regard to mucosal mast cell response to infection with H. diminuta, DA rats can be looked on as high responders and F344/N rats as low responders.
Department of Parasitology, Hamamatsu University School of Medicine, Japan.
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Ishih
D000818:Animals; D002452:Cell Count; D006925:Hymenolepiasis / Q000276:immunology* / Q000469:parasitology; D006926:Hymenolepis / Q000276:immunology*; D007111:Immunity, Cellular; D008297:Male; D008407:Mast Cells / Q000276:immunology*; D009092:Mucous Membrane / Q000473:pathology; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains