Sweet's syndrome--therapy with cyclosporin.
We report the case of a 39-year-old female patient suffering from Sweet's syndrome after an upper respiratory tract infection. Cyclosporin A at a dose of 10 mg/kg per day was given as initial treatment. Skin lesions and general malaise resolved within 9 days. The cyclosporin dose was decreased within 21 days, without recurrence of the eruption. Cyclosporin is a potent inhibitor of T lymphocytes, but affects granulocyte and monocyte functions as well. Success of treatment in our case shows that cyclosporin represents an alternative to steroid treatment in patients with Sweet's syndrome.
Department of Dermatology, University of Erlangen-Nuremberg, Germany.
P
P
von den Driesch
C
C
Steffan
A
A
Zöbe
O P
OP
Hornstein
D000328:Adult; D016572:Cyclosporine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology; D016463:Sweet Syndrome / Q000188:drug therapy* / Q000473:pathology
D016572:Cyclosporine