Association of Wilms' tumor and intracranial hemorrhage due to arteriovenous malformation.
A high incidence of congenital malformations associated with Wilms' tumor has been recognized lately. Aniridia, hemihypertrophy, and urinary tract anomalies are among the most frequently reported. Anomalies of the central nervous system associated with Wilms' tumor are rare. We report a previously healthy 4-year-old girl who presented with an intracranial hemorrhage secondary to a ruptured arteriovenous malformation. A routine abdominal examination revealed a large right-sided Wilms' tumor. The question generated by the coexistence of these two uncommon disorders in one individual is whether there is a genetic or other relationship between them, or whether this is merely a coincidental occurrence. The question at this point is unanswered and must await demonstration of additional, similar cases.
Division of Pediatric Neurology, Schneider Children's Hospital, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, NY 11042.
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Rosenn
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Maytal
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Lantos
D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis; D014695:Cerebral Ventriculography; D002675:Child, Preschool; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000175:diagnosis; D007680:Kidney Neoplasms / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000150:complications* / Q000175:diagnosis