[Studies on urinary metabolites of calusterone in man].
The metabolites of calusterone (17 beta-OH-7 beta, 17 alpha-dimethyl-androst-4-ene-3-one) in man has been investigated by GC/MS. After oral administration, the parent compound and seven metabolites were detected in the conjugated fraction. The extraction and fractionation of these metabolites were achieved by using XAD-2 column. The sample was derivatized with MSTFA/TMSI before GC/MS analysis. The mass spectra of the metabolites are presented and the metabolic pathway was discussed.
National research Institute of Sports Medicine, Beijing.
Y Z
YZ
Zhang
X
X
Liu
C J
CJ
Zhang
L
L
Ye
D004300:Doping in Sports; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008777:Methyltestosterone / Q000031:analogs & derivatives* / Q000378:metabolism / Q000652:urine
C073055:calusterone; D008777:Methyltestosterone