Application of artificial neural networks for prokaryotic transcription terminator prediction.
Artificial neural networks (ANN) to predict terminator sequences, based on a feed-forward architecture and trained using the error back propagation technique, have been developed. The network uses two different methods for coding nucleotide sequences. In one the nucleotide bases are coded in binary while the other uses the electron-ion interaction potential values (EIIP) of the nucleotide bases. The latter strategy is new, property based and substantially reduces the network size. The prediction capacity of the artificial neural network using both coding strategies is more than 95%.
Chemical Engineering Division, National Chemical Laboratory, Pune, India.
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Nair
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Tambe
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Kulkarni
D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry; D005815:Genetic Code; D016571:Neural Networks, Computer; D011387:Prokaryotic Cells; D012045:Regulatory Sequences, Nucleic Acid; D014158:Transcription, Genetic
D004247:DNA