Effect of theophylline on periodic breathing in congestive heart failure measured by transcutaneous oxygen monitoring.
The effect of theophylline on periodic breathing was measured by transcutaneous oxygen monitoring in 7 patients suffering from chronic congestive heart failure. Theophylline significantly decreased the frequency of Cheyne-Stokes breathing. Transcutaneous oxygen monitoring proved to be a useful method to follow changes in the breathing pattern. The suggested mechanism of action of theophylline in reducing the incidence of periodic breathing is blockade of adenosine receptors.
Tomcsányi
J
J
National Korányi Institute for Tuberculosis and Pulmonology, Budapest, Hungary.
Karlócai
K
K
D000328:Adult; D000368:Aged; D001785:Blood Gas Monitoring, Transcutaneous; D002908:Chronic Disease; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012119:Respiration / Q000187:drug effects*; D013806:Theophylline / Q000494:pharmacology*
D013806:Theophylline