[Treatment of diastolic dysfunction of the left ventricle].
Numerous studies have already recognized the importance of diastole in the pathogenesis of congestive heart failure. Non-invasive evaluations are based particularly on echo-Doppler, on radionuclide angiography and on cine-nuclear magnetic resonance: they have enabled an accurate evaluation of diastolic function and dysfunction, although invasive hemodynamic study maintains a gold standard position. All these methods of study have consented the identification of 3 basic components (anatomic and functional): active relaxation, passive elastic relaxation, atrial function. The Authors have identified the causes of diastolic failure with a particular attention to the various components of diastole. They have analyzed the implication of therapy on the basis of a clear understanding of the etiology, pathogenesis and pathophysiology of the underlying cardiac disease.
Cattedra di Cardiologia, Università degli Studi, Modena.
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Zennaro
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Tondi
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Cappello
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Geraci
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Ricci
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Nardini
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Mattioli
D003971:Diastole / Q000502:physiology; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D016277:Ventricular Function, Left / Q000502:physiology
La terapia della disfunzione diastolica del ventricolo sinistro.