The effects of monocular enucleation on the representation of auditory space in the superior colliculus of the guinea-pig.
Multi-unit responses, to free-field auditory stimuli, in the superior colliculus were investigated in guinea-pigs following earlier removal of one eye. Enucleation resulted in disruption of the normal tuning parameter values and of the topographical precision of auditory responses in the SC both ipsilateral and contralateral to the enucleated eye. These data demonstrate that monocular enucleation prevents the normal development of the superior collicular auditory space map.
Withington
D J
DJ
Department of Physiology, University of Leeds, UK.
Binns
K E
KE
Ingham
N J
NJ
Thornton
S K
SK
D000375:Aging / Q000502:physiology; D000818:Animals; D001309:Auditory Threshold / Q000502:physiology; D004567:Electrodes, Implanted; D015353:Eye Enucleation; D006168:Guinea Pigs; D013017:Sound Localization / Q000502:physiology*; D013028:Space Perception / Q000502:physiology*; D013477:Superior Colliculi / Q000502:physiology*; D015349:Vision, Monocular / Q000502:physiology*