[Treatment of experimental glanders with combinations of sulfazine or sulfamonomethoxine with trimethoprim].
Combinations of sulfazine or sulfamonomethoxine with trimethoprim were found to be efficient in the prophylaxis and treatment of experimental glanders simulated by various strains and doses of the causative agent, the treatment being started and terminated at various periods. The efficacy indices and treatment schemes were elaborated. By the efficacy indices the sulfazine combination with trimethoprim was shown to be 2-3 times more efficient than the sulfamonomethoxine combination with trimethoprim.
V P
VP
Batmanov
D000818:Animals; D000900:Anti-Bacterial Agents; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005896:Glanders / Q000188:drug therapy* / Q000517:prevention & control; D006736:Horses; D013411:Sulfadiazine / Q000008:administration & dosage; D013422:Sulfamonomethoxine / Q000008:administration & dosage; D014295:Trimethoprim / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D013411:Sulfadiazine; D014295:Trimethoprim; D013422:Sulfamonomethoxine
Lechenie éksperimental'nogo sapa sochetaniem sul'fazina ili sul'famonometoksina s trimetoprimom.