[Examination of the heterogeneity of heparin. IV. Crude heparin].
By means of gel chromatography on Sephadex G-15 crude heparin produced at Polfa into four components (71.6%-I, 5.1%-II, 5.8%-III and 17.5%-IV). These components were characterized by different anticoagulant activity (I-110 IU/mg, II-40.0 IU/mg, III-2.0 IU/mg and IV-55.0 IU/mg), what was connected with variable values of molecular weight and of sulphate groups, glucosamine and uronic acids contents.
Jarzebiński
J
J
Zakład Analizy Leków, Instytut Nauki o Leku, Warszawa.
Gryz
K
K
Tońska
S
S
D002850:Chromatography, Gel; D006493:Heparin / Q000032:analysis*; D008970:Molecular Weight
D006493:Heparin
Badania heterogeniczności heparyny. IV. Heparyna surowa.