Gene targeting and its application to the study of B-cell development.
The use of gene targeting technology for the study of gene functions in vivo continues to expand. The application of this technology as well as further improvements in the technology itself enable us to examine the influence of various genetic elements and gene products on B-lymphocyte development and function.
Gu
H
H
Institute for Genetics, University of Cologne, Germany.
D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology*; D004251:DNA Transposable Elements / Q000235:genetics; D004268:DNA-Binding Proteins; D015322:Gene Rearrangement, B-Lymphocyte; D005821:Genetic Techniques; D005822:Genetic Vectors / Q000235:genetics; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics; D011506:Proteins / Q000235:genetics; D011995:Recombination, Genetic
D004251:DNA Transposable Elements; D004268:DNA-Binding Proteins; D011506:Proteins; C499308:Rag2 protein, mouse; C064655:V(D)J recombination activating protein 2