Identification of sigma receptors in lacrimocytes and their therapeutic implication in dry eye syndrome.
Schoenwald
R D
RD
Division of Pharmaceutics, College of Pharmacy, University of Iowa, Iowa City 52242.
Barfknecht
C F
CF
Shirolkar
S
S
Xia
E
E
Ignace
C C
CC
D000287:Administration, Topical; D000818:Animals; D001964:Bromhexine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology; D002217:Carbachol / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D015352:Dry Eye Syndromes / Q000188:drug therapy*; D005136:Eye Proteins / Q000378:metabolism; D005260:Female; D007765:Lacrimal Apparatus / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009883:Ophthalmic Solutions; D011817:Rabbits; D017480:Receptors, sigma / Q000302:isolation & purification*; D013666:Tears / Q000378:metabolism
D005136:Eye Proteins; D009883:Ophthalmic Solutions; D017480:Receptors, sigma; C042434:tear proteins; D002217:Carbachol; D001964:Bromhexine