Chronic fatigue: a peculiar evolution of eosinophilia myalgia syndrome following treatment with L-tryptophan in four Italian adolescents.
We describe four Italian adolescents in whom a persistent, debilitating fatigue appeared after therapeutic ingestion of products containing L-tryptophan and subsequent to the development of a transient rise in eosinophil count and severe myalgia (Eosinophilia Myalgia Syndrome-EMS). Their clinical picture was indistinguishable from that of the so-called Chronic Fatigue Syndrome. A chronic fatigue may occur after diverse triggering agents and its represents the peculiar clinical evolution of these four paediatric cases of EMS.
Istituto di Clinica Medica I, Università La Sapienza, Roma, Italy.
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Priori
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Conti
F L
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Luan
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Arpino
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Valesini
D000293:Adolescent; D016603:Eosinophilia-Myalgia Syndrome / Q000139:chemically induced / Q000150:complications*; D015673:Fatigue Syndrome, Chronic / Q000209:etiology*; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D014364:Tryptophan / Q000009:adverse effects*
D014364:Tryptophan