Prognostic indicators in adult cerebral malaria: a study in Burundi, an area of high prevalence of HIV infection.
We examined the possible risk factors for poor prognostic in cerebral malaria in 31 adults from Burundi, an area of high prevalence rate of HIV-1 infection. Depth of coma, temperature, vomiting, seizures, parasite load, or anaemia did not modify the outcome. High levels of creatinine, bilirubin, and/or lactates were indicators of poor prognostic. HIV-1 infection did not affect the clinical or biological presentation of cerebral malaria, and did not appear to influence the outcome.
Niyongabo
T
T
Centre Hospitalo-Universitaire de Kamenge, Bujumbura, Burundi.
Deloron
P
P
Aubry
P
P
Ndarugirire
F
F
Manirakiza
F
F
Muhirwa
G
G
Ndayiragije
A
A
Brelivet
J C
JC
D000328:Adult; D000818:Animals; D001663:Bilirubin / Q000097:blood; D002063:Burundi / Q000453:epidemiology; D003404:Creatinine / Q000097:blood; D005260:Female; D015600:Glasgow Coma Scale; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology*; D015497:HIV-1 / Q000276:immunology; D006801:Humans; D007262:Infusions, Intravenous; D008107:Liver Diseases / Q000209:etiology / Q000401:mortality; D016779:Malaria, Cerebral / Q000150:complications / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology*; D008297:Male; D010963:Plasmodium falciparum / Q000302:isolation & purification; D015995:Prevalence; D011379:Prognosis; D011803:Quinine / Q000008:administration & dosage; D051437:Renal Insufficiency / Q000209:etiology / Q000401:mortality; D012307:Risk Factors
D015483:HIV Antibodies; D011803:Quinine; D003404:Creatinine; D001663:Bilirubin