Treatment of 'Old World' cutaneous leishmaniasis with aminosidine ointment: results of an open study in London.
Five preparations of ointment containing aminosidine were used to treat lesions of 'Old World' cutaneous leishmaniasis. A preparation containing 12-15% aminosidine with 10% urea in white soft paraffin was nontoxic. 23 of 27 patients treated healed in a mean of 6.7 weeks, the ointment being applied daily for up to 12 weeks.
Bryceson
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AD
Hospital for Tropical Diseases, London, UK.
Murphy
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A
Moody
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AH
D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy*; D009824:Ointments; D010303:Paromomycin / Q000627:therapeutic use*; D016896:Treatment Outcome
D009824:Ointments; D010303:Paromomycin