[Injection of 5-fluorouracil in the treatment of tubal pregnancy through salpingo-catheter under hysteroscopy].
Seventeen women with unruptured tubal pregnancy were given 5-FU through salpingo-catheter under hysteroscopy. In one case the injection failed because the tube opening could not be found. The success rate of salpingo-catheterization was 94.12% (16/17). The cure rate for the tubal pregnancies was 88.24% (15/17). 12 cases received injection once and 3 cases twice. The dose of 5-FU per injection was 250 mg in 10 ml solution. Serum beta-hCG test became negative in 7 to 14 days after the treatment, and signs and symptoms disappeared. Salpingography were done in 8 cases after 2 to 3 months, and all the diseased tubes were found patient. There was little side effects due to this treatment, which is more effective, convenient and less traumatic than injecting 5-FU to the affected site through laparoscopy or systemic administration. It may turn out to be an effective, simple, safe and acceptable new method for treating early tubal pregnancy.
Xie
Q H
QH
Women and Children's Hospital of Foshan, Guangdong.
Liu
X C
XC
Liu
S Y
SY
D000328:Adult; D002404:Catheterization; D005187:Fallopian Tubes; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D015907:Hysteroscopy; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000188:drug therapy*
D005472:Fluorouracil