[HIV infection, fever and cholestasis].
A 35-year-old Swiss woman with AIDS experienced fever, jaundice and cough. Laboratory evaluation revealed signs of an infection and cholestasis. The examination by ultrasound showed thickening of the intra- and extrahepatic bile ducts and gallbladder wall, without dilatation or stones. Endoscopic retrograde cholangiography demonstrated diffuse sclerosing cholangitis like lesions in the biliary tract and confirmed the diagnosis of a HIV related cholangiopathy. The cause was a cytomegalovirus infection as shown by liver biopsy with detection of cytomegalovirus early antigen. The treatment with ganciclovir was of some efficacy with improvement of jaundice.
Departement für Innere Medizin, Universitätsspital Zürich.
S
S
Giezendanner
G
G
Zala
J
J
Jost
P
P
Greminger
C
C
Meyenberger
D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000328:Adult; D015209:Cholangitis, Sclerosing / Q000209:etiology* / Q000382:microbiology; D002779:Cholestasis / Q000209:etiology*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005334:Fever / Q000209:etiology; D015658:HIV Infections / Q000150:complications*; D006801:Humans
HIV-Infektion, Fieber und Cholestase.