Forehead and forearm skin blood flows in newborn infants measured by laser Doppler flowmetry: short-term variability and relationship to sleep states.
Laser doppler flowmeters were used to measure blood flow in the skin of the forehead and volar surface of the forearm of infants at 2-9 days of age, and at 8-12 weeks of age. At both ages mean skin blood flow was higher during active sleep compared to quiet sleep. In infants up to 9 days of age, mean skin blood flow was higher in forehead skin compared to forearm skin. Skin blood flow was highly variable at both recording sites, and was significantly higher and more variable during active compared to quiet sleep in the forehead, but not in the forearm. The results indicate that recordings of skin blood flow over at least two cycles of active and quiet sleep are needed to describe the normal variation with sleep state. The factors which regulate forehead and forearm skin blood flows may differ in importance between the two sites, perhaps reflecting the different thermoregulatory importance of cutaneous blood flow in the forehead and forearm.
Johnston
R
R
Department of Physiology, Monash University, Clayton, Victoria, Australia.
Walker
D W
DW
Adamson
T M
TM
Westerman
R A
RA
D005542:Forearm / Q000098:blood supply*; D005546:Forehead / Q000098:blood supply*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017078:Laser-Doppler Flowmetry; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply*; D012894:Sleep Stages / Q000502:physiology*