In vivo forces in the anterior cruciate ligament: direct measurements during walking and trotting in a quadruped.
In vivo forces in the anterior cruciate ligament (ACL) were measured in three adult goats during quiet standing and during gait (walking or trotting). A modified pressure transducer (MPT) was implanted within the anteromedial band of the ligament to make direct measurements of ACL force. One or two days following implantation, measurements were made of ACL force, knee joint flexion angle, ground reaction forces, and speed of locomotion. MPT calibration was performed in vitro using anteroposterior displacement tests at six flexion angles. The ACL was loaded during quiet standing (30-61 N) and during the stance phase of gait. Peak ACL forces were achieved within the first 40% of stance, with magnitudes ranging from 63 to 124 N during walking and from 102 to 150 N during trotting. The average ACL force during the stance phase ranged from 34 to 68 N while walking and from 46 to 69 N while trotting. The partial correlations between peak ACL force and speed, and between average ACL force and speed, were both statistically different from zero (p < 0.01). ACL forces dropped to zero during the swing phase in all trials. ACL forces were less than 15 N throughout swing in two of the animals, both of which did not extend their knees during gait beyond 20 degrees from full extension. In the animal which did show knee extension beyond 40 degrees (20 degrees from full extension), ACL loading occurred during late swing. The magnitude of the peak ACL force during late swing was significantly correlated with the extent of knee extension in this animal.
National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
J P
JP
Holden
E S
ES
Grood
D L
DL
Korvick
J F
JF
Cummings
D L
DL
Butler
D I
DI
Bylski-Austrow
D000818:Animals; D016118:Anterior Cruciate Ligament / Q000502:physiology*; D005260:Female; D005269:Femur / Q000033:anatomy & histology / Q000502:physiology; D005684:Gait / Q000502:physiology; D006041:Goats / Q000502:physiology*; D007719:Knee Joint / Q000033:anatomy & histology / Q000502:physiology; D016059:Range of Motion, Articular / Q000502:physiology; D012399:Rotation; D012420:Running / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013314:Stress, Mechanical; D013977:Tibia / Q000033:anatomy & histology / Q000502:physiology; D014160:Transducers, Pressure; D016138:Walking / Q000502:physiology*; D016474:Weight-Bearing / Q000502:physiology