Oat cell carcinoma of the lung in patients with CLL.
Two malignancies in one patient was a remote possibility in the distant past, but currently more of these cases are being seen. At our institution, several patients with Chronic Lymphocytic Leukemia (CLL) were seen to develop oat cell carcinoma of the lung. The decreased immunity and B-cell dysfunction in CLL probably accounts for this secondary malignancy. We are presenting these cases to alert physicians of combined malignancies in a patient with increased aggressiveness of oat cell carcinoma.
University of Louisville, Department of Medicine, School of Medicine, KY.
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Rahal
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Cornelius
D000368:Aged; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D007629:Kentucky / Q000453:epidemiology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis / Q000453:epidemiology*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D012307:Risk Factors