Therapeutic thrombocytapheresis: a review of 132 patients.
Therapeutic thrombocytapheresis has been used is an attempt to obtain a rapid cytoreduction in thrombocythemic patients, in order to prevent or reduce thrombosis or bleeding complications. Long-term cytoreduction has to be performed with chemotherapy. We have treated with thrombocytapheresis 132 patients with increased platelet count (76 with thrombosis and/or bleeding) due to splenectomy, essential thrombocythemia and other myeloproliferative disorders: a comparative study has been performed to find a platelet count that could be helpful in preventing thrombotic and hemorrhagic complications and the role of diagnosis in predicting patient's risk.
Adami
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Division of Immunohematology and Transfusion Services, Galliera Hospital, Genova, Italy.
D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy; D010983:Plateletpheresis / Q000295:instrumentation; D011087:Polycythemia Vera / Q000628:therapy; D013922:Thrombocytosis / Q000628:therapy