[Churg-Strauss syndrome: personnel case report and literature review].
A 58-year-old male presented with a three years history of atopic asthma, fluctuating eosinophilia and, at the moment of diagnosis, systemic vasculitis of brutal onset affecting skin and peripheral nerves. Demonstration of eosinophilic infiltrates and granulomata in involved tissues confirmed the clinical diagnosis of Churg-Strauss syndrome. Therapy with high-dose methylprednisolone and cyclophosphamide was followed by normalization of blood cell count and partial recovery of clinical manifestations, with persisting damage to the peripheral nerves.
Volz
A
A
Départment de Médecine Interne, Hôpital St. Pierre, Bruxelles.
Renard
N
N
Alame
T
T
Efira
A
A
D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004802:Eosinophilia / Q000473:pathology; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D014650:Vasa Nervorum / Q000473:pathology
D003520:Cyclophosphamide; D008775:Methylprednisolone
Syndrome de Churg-Strauss: observation personnelle et revue de la littérature.