[Our clinical experience in treating endometriosis genitalis externa with the preparation Danoval].
By means of the serum level of estradiol and the vaginal smear indexes the antigonadotropic activity of the preparation Danoval (2-3-isoxasol-17-ethinyltestosterone) is indirectly evaluated on 15 infertility patients with laparoscopic proved endometriosis. After 5 month's course of treatment with 400 mg daily the level of estradiol decreased from 1.54 to 0.31 nmol/l, IA from 20.8 to 10.4 and IP from 32 to 17.3. The side effects are slight and descend from the pharmacological properties of the preparation. Two patients became pregnant in three months after the treatment.
B
B
Nalbanski
V
V
Novachkov
E
E
Rachev
A
A
Nikolov
S
S
Stoianov
M
M
Katsarova
A
A
Maleeva
D000291:Adnexal Diseases / Q000097:blood / Q000188:drug therapy*; D000328:Adult; D003613:Danazol / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D004715:Endometriosis / Q000097:blood / Q000188:drug therapy*; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans
D004958:Estradiol; D003613:Danazol
Nashiiat klinichen opit za lechenie na endometriosis genitalis externa s preparata Danoval.