The mechanism by which serpins inhibit thrombin and other serine proteinases.
Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232.
P A
PA
Patston
P G
PG
Gettins
M
M
Schapira
D000494:Allosteric Regulation; D000818:Animals; D006025:Glycosaminoglycans / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D011487:Protein Conformation; D012697:Serine Endopeptidases / Q000737:chemistry / Q000378:metabolism*; D015843:Serpins / Q000737:chemistry* / Q000494:pharmacology*; D013917:Thrombin / Q000037:antagonists & inhibitors* / Q000737:chemistry
D006025:Glycosaminoglycans; D015843:Serpins; D012697:Serine Endopeptidases; D013917:Thrombin