Surface coil cardiac tagging and 31P spectroscopic localization with B1-insensitive adiabatic pulses.
A technique is presented for MRI tagging in the presence of inhomogeneous B1 fields. A rectangular tagging grid is produced with B1-insensitive adiabatic pulses in a magnetization preparation period that precedes image acquisition. Phantom results demonstrate that the method is well-suited to surface coil experiments. The technique is applied to a canine model of myocardial ischemia to track the spatially dependent wall motion of the left ventricle during the cardiac cycle. Transmural 31P spectra are acquired from the same double-tuned surface coil, with tagging and spectroscopy performed for the first time, during normal, ischemic, and recovery conditions for the same animal.
Department of Biochemistry, University of Minnesota Medical School, Minneapolis 55455.
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K
Hendrich
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Y
Xu
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SG
Kim
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Uğurbil
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D003331:Coronary Vessels / Q000502:physiology; D003971:Diastole / Q000502:physiology; D004285:Dogs; D005583:Fourier Analysis; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008280:Magnetics; D008955:Models, Cardiovascular; D008961:Models, Structural; D017202:Myocardial Ischemia / Q000378:metabolism*; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism; D010758:Phosphorus; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology
D010710:Phosphates; D010725:Phosphocreatine; D010758:Phosphorus; D000255:Adenosine Triphosphate