[A comparative evaluation of the effect of glurenorm and sulfonylurea preparations on the intravascular microcirculatory indices in type-II diabetes mellitus].
Analysis of the effects of glurenorm and some sulfonylurea drugs, such as maninil, minidiab, chlorpropamide, on some parameters of intravascular microcirculation has demonstrated the specific features of this drug. Though all these hypoglycemic agents favorably influence the microcirculation when carbohydrate metabolism compensation is attained, glurenorm improved the status of formed elements of the blood (red cell and platelet aggregation) more noticeably than the rest drugs, which fact recommends it as a drug of choice for patients with type II medium-severe diabetes with the predominant involvement of the cellular component of the microcirculation.
Kakhnovskiĭ
I M
IM
Koroleva
T V
TV
Zakharchenko
V N
VN
Larionov
S N
SN
D000328:Adult; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy*; D003925:Diabetic Angiopathies / Q000097:blood / Q000188:drug therapy*; D004341:Drug Evaluation; D004903:Erythrocyte Aggregation / Q000187:drug effects; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects; D013453:Sulfonylurea Compounds / Q000627:therapeutic use*; D013997:Time Factors
D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; C010969:gliquidone
Sravnitel'naia otsenka vliianiia gliurenorma i nekotorykh preparatov sul'fonilmocheviny na pokazateli vnutrisosudistoĭ mikrotsirkuliatsii pri sakharnom diabete II tipa.