The effect of prebrushing mouthrinse solutions on the desorption of albumin from apatite.
This study evaluated the desorption of radiolabelled albumin from synthetic hydroxypatite by 4 commercial prebrushing solutions: Lysoplac (containing chlorhexidine), Plax (sodium benzoate), Acti-Brush (triclosan), and Sanogyl (sodium fluoride). In 3 min, Lysoplac and Plax were found to desorb about 90% of albumin while Acti-Brush and Sanogyl failed to desorb hardly any albumin in 15 min. The desorbing effectiveness of the test solutions was not due to their pH, because when buffer solution was being tested in different ionic strengths at pH range 6-8, it appeared to desorb less than 3% of adsorbed albumin, irrespective of the pH used. The results obtained cannot, however, be directly applied to the clinical situation where much more complex interactions occur than what were tested under the present in vitro conditions.
Haikel
Y
Y
Faculté de Chirurgie Dentaire, Université Louis Pasteur, Strasbourg, France.
Voegel
J C
JC
Meurman
J H
JH
D000327:Adsorption; D000418:Albumins / Q000737:chemistry*; D001565:Benzoates / Q000627:therapeutic use; D019817:Benzoic Acid; D002710:Chlorhexidine / Q000627:therapeutic use; D003773:Dental Plaque / Q000188:drug therapy*; D017886:Durapatite / Q000737:chemistry*; D006801:Humans; D007457:Iodine Radioisotopes; D009067:Mouthwashes / Q000627:therapeutic use*; D012967:Sodium Dodecyl Sulfate / Q000627:therapeutic use; D012969:Sodium Fluoride / Q000627:therapeutic use; D014260:Triclosan / Q000627:therapeutic use
D000418:Albumins; D001565:Benzoates; D007457:Iodine Radioisotopes; D009067:Mouthwashes; C070868:Plax; D012967:Sodium Dodecyl Sulfate; D014260:Triclosan; D019817:Benzoic Acid; D012969:Sodium Fluoride; D017886:Durapatite; D002710:Chlorhexidine