[HPV genital infections + CIN. The immunological patterns, loop electroablation and beta-interferon].
Sixteen patients with genital HPV associated with CIN were treated with electroablation using a diathermic loop and immunomodulation with human beta interferon. Changes in immunological, cyto-histological and clinical parameters were observed pre- and post-treatment. Thirteen cases showed an excellent response. Disease was persistent in three cases. The authors report an improvement, even if statistically non-significant, in some immune parameters and confirm the value of associating physical therapy with immunomodulating treatment.
Vitale
G
G
Divisione di Ostetricia e Ginecologia, USSL 9 Presidio Ospedaliero, S. Vito al Tagliamento, Pordenone.
Linciano
M
M
Salamanca
S
S
Ferrari
P
P
D000328:Adult; D003131:Combined Modality Therapy; D003218:Condylomata Acuminata / Q000276:immunology* / Q000628:therapy; D004564:Electrocoagulation; D005260:Female; D005831:Genital Diseases, Female / Q000276:immunology* / Q000628:therapy; D006801:Humans; D016899:Interferon-beta / Q000627:therapeutic use*; D008875:Middle Aged; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000276:immunology* / Q000628:therapy; D012074:Remission Induction; D014412:Tumor Virus Infections / Q000276:immunology* / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000276:immunology* / Q000628:therapy; D002578:Uterine Cervical Dysplasia / Q000276:immunology* / Q000628:therapy
D016899:Interferon-beta
Infezioni genitali da HPV + CIN. Patterns immunologici, elettroablazione con ansa e beta-interferone.