Immunohistochemical expression of tissue polypeptide specific (TPS) antigen in normal and neoplastic tissues.
TPS was determined by immunohistochemistry in 44 different tissues (normal and pathological) from various organs such as cervix, endometrium, breast, stomach, bowel and bladder. TPS was expressed in several physiologic situations: in different phases of the endometrial cycle and in cervical metaplasia. In other organs such as the breast and the bladder this antigen shows its highest expression in invasive neoplasias. Therefore, it could be utilized in the follow-up of these neoplasias.
Calledra di Citopatologia I, Università La Sapienza, Roma, Italy.
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D000941:Antigens / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D001943:Breast Neoplasms / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000473:pathology; D004717:Endometrium / Q000166:cytology / Q000473:pathology; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D005833:Genital Neoplasms, Female / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry / Q000379:methods*; D008297:Male; D010452:Peptide Biosynthesis; D010455:Peptides / Q000032:analysis*; D011471:Prostatic Neoplasms / Q000473:pathology*; D012016:Reference Values; D013274:Stomach Neoplasms / Q000473:pathology; D019396:Tissue Polypeptide Antigen; D001749:Urinary Bladder Neoplasms / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology; D014846:Vulvar Neoplasms / Q000473:pathology
D000941:Antigens; D014408:Biomarkers, Tumor; D010455:Peptides; D019396:Tissue Polypeptide Antigen