Infiltration of the carotid artery by cavernous sinus meningioma.
Intracranial meningiomas are known to infiltrate surrounding structures such as the calvaria and dural sinuses, and the brain itself. The issue of whether meningiomas invade major intracranial arteries is of clinical importance, particularly in the case of meningiomas of the cavernous sinus. If a meningioma has not invaded the carotid artery wall, complete tumor removal may be accomplished with careful dissection from the carotid artery; however, if the tumor has infiltrated the wall of the carotid artery, complete removal may require sacrifice of the artery. To determine whether cavernous sinus meningiomas invade the carotid artery, the authors retrospectively reviewed the histopathology of 19 consecutively treated individuals whose carotid artery was sacrificed during removal of a meningioma involving the cavernous sinus. Patients were selected for carotid artery resection based on preoperative magnetic resonance imaging studies demonstrating complete encasement of the artery. Reconstruction of the carotid artery was planned depending on the results of preoperative balloon test occlusion with blood flow determinations. None of the 19 patients had pathological evidence of malignant tumor. Eight individuals (42%) were found to have infiltration of the carotid artery by meningioma. In five cases, focal involvement of the adventitia of the carotid artery wall was noted and, in three, the vessel was infiltrated up to the tunica muscularis. In no case was the tunica muscularis invaded by tumor. Thus, meningiomas of the cavernous sinus do infiltrate the internal carotid artery and, in order to completely resect these lesions and effect a surgical cure, it may be necessary to sacrifice the carotid artery with or without reconstruction.
Kotapka
M J
MJ
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania.
Kalia
K K
KK
Martinez
A J
AJ
Sekhar
L N
LN
D002339:Carotid Arteries / Q000473:pathology; D002340:Carotid Artery Diseases / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D016893:Carotid Stenosis / Q000473:pathology / Q000601:surgery; D002426:Cavernous Sinus / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D002560:Cerebrovascular Circulation / Q000502:physiology; D006801:Humans; D008579:Meningioma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D009361:Neoplasm Invasiveness; D012039:Regional Blood Flow / Q000502:physiology; D012189:Retrospective Studies; D012501:Saphenous Vein / Q000637:transplantation; D012888:Skull Neoplasms / Q000473:pathology; D014652:Vascular Diseases / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery