Analytical investigations of Glipolamid--a new antidiabetic drug.
A qualitative and quantitative analysis of an antidiabetic drug Glipolamid was developed. The qualitative analysis included the determination of the physical-chemical properties (UV-VIS, IR, NMR spectra, hRf) and characteristic reactions. The quantitative assay included the following methods of the determination of Glipolamid in substance as well as in tablets: alkalimetric in non-aqueous medium, acidimetric and spectrophotometric.
Department of Pharmaceutical Chemistry, Institute of Drug Science, School of Medicine, Warsaw, Poland.
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Gajewska
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Somogi
D006863:Hydrogen-Ion Concentration; D007004:Hypoglycemic Agents / Q000032:analysis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008970:Molecular Weight; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013453:Sulfonylurea Compounds / Q000032:analysis / Q000737:chemistry*; D013607:Tablets; D017186:Titrimetry
D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; D013607:Tablets; C009971:glipalamide