[Clinical effectiveness, adverse effects and complications of intravenous administration of ATP in paroxysmal tachycardia].
Forty patients with paroxysmal tachycardias were studied. After intravenous bolus administration of ATP, 10-20 mg sinus rhythm restored in 24 patients with nodal reciprocal tachycardia or Wolff-Parkinson-White syndrome. In patients with ventricular tachycardia, antidromal paroxysmal tachycardia in the presence of the Wolff-Parkinson-White syndrome and atrial flutter, bolus administration of ATP made the diagnosis more precise. Adverse reactions were seen in 75% of patients. There was a case of cardiac asystole, 50 sec long, with symptoms of clinical death. The sick sinus syndrome and atrioventricular block are regarded as a contraindication for bolus administration of ATP due to binodal dysfunction induced by the agent.
Lipnitskiĭ
T N
TN
Denisiuk
V I
VI
Randin
A G
AG
Stepaniuk
A V
AV
Muravitskiĭ
O V
OV
D000255:Adenosine Triphosphate / Q000008:administration & dosage* / Q000009:adverse effects; D000293:Adolescent; D000328:Adult; D000368:Aged; D000075202:Contraindications; D003327:Coronary Disease / Q000150:complications; D005260:Female; D006327:Heart Block / Q000150:complications; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012804:Sick Sinus Syndrome / Q000150:complications; D013614:Tachycardia, Paroxysmal / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D014927:Wolff-Parkinson-White Syndrome / Q000188:drug therapy
D000255:Adenosine Triphosphate
Klinicheskaia éffektivnost', pobochnye deĭstviia i oslozhneniia vnutrivennogo vvedeniia ATF pri paroksizmal'nykh takhikardiiakh.