Cervical antibodies in patients with oral herpes simplex virus type 1 (HSV-1) infection: local anamnestic responses after genital HSV-2 infection.
Herpes simplex virus (HSV)-specific immunoglobulin A, immunoglobulin G, and secretory-component-containing immunoglobulins were identified in cervical and salivary secretions from six subjects with oral HSV type 1 (HSV-1) infections. Anamnestic cervical and salivary antibody responses were detected in two HSV-1-seropositive women with newly acquired genital HSV-2 infections. These data implicate the common mucosal immune system in antibody responses to HSV.
Department of Laboratory Medicine, University of Washington School of Medicine, Seattle 98195.
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D000328:Adult; D000914:Antibodies, Viral / Q000276:immunology*; D002584:Cervix Uteri / Q000276:immunology* / Q000382:microbiology; D005260:Female; D006558:Herpes Genitalis / Q000276:immunology*; D018259:Herpesvirus 1, Human / Q000276:immunology; D018258:Herpesvirus 2, Human / Q000276:immunology; D006801:Humans; D012469:Salivary Glands / Q000276:immunology / Q000382:microbiology; D013283:Stomatitis, Herpetic / Q000276:immunology*
D000914:Antibodies, Viral