[Magnesium therapy in preeclampsia and HELLP syndrome--studies of pathophysiology].
Aggregation und Serotonin-release were investigated depending on plasma magnesium levels. High magnesium levels inhibit the platelet function, which is stimulated in preeclamptic patients. Magnesium-infusions therefore might be of therapeutical use in SIH-patients by reducing the platelet function.
Hettenbach
A
A
Frauenklinik, Klinik am Eichert, Göppingen.
Possover
M
M
Müller
E
E
Stutz
B
B
D004305:Dose-Response Relationship, Drug; D005260:Female; D017359:HELLP Syndrome / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D066298:In Vitro Techniques; D007262:Infusions, Intravenous; D008274:Magnesium / Q000097:blood; D008278:Magnesium Sulfate / Q000008:administration & dosage* / Q000493:pharmacokinetics; D015539:Platelet Activation / Q000187:drug effects* / Q000502:physiology; D010974:Platelet Aggregation / Q000187:drug effects* / Q000502:physiology; D011225:Pre-Eclampsia / Q000097:blood / Q000188:drug therapy*; D011247:Pregnancy; D012701:Serotonin / Q000097:blood*
D012701:Serotonin; D008278:Magnesium Sulfate; D008274:Magnesium
Magnesiumtherapie bei Präeklampsie und beim HELLP-Syndrom--Untersuchungen zur Pathophysiologie.