Localization on the cell surface of streptococcal protein antigen A.
The cellular localization of the major surface protein SpaA of Streptococcus sobrinus 6715 was examined by immunoelectron microscopy with rabbit polyclonal antibodies directed against purified SpaA protein. Immunoelectron microscopic analysis of thin sections of S. sobrinus cells revealed that the SpaA protein is associated with the fibrillar fuzzy coat of S. sobrinus cells and appears to be distributed over the entire surface of S. sobrinus cells.
Department of Microbiology, Meharry Medical College, Nashville, TN 37208.
R G
RG
Holt
H J
HJ
Wynder
D000942:Antigens, Bacterial / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D001426:Bacterial Proteins / Q000032:analysis*; D007150:Immunohistochemistry; D008562:Membrane Glycoproteins; D016253:Microscopy, Immunoelectron; D016986:Streptococcus sobrinus / Q000276:immunology* / Q000648:ultrastructure
D000942:Antigens, Bacterial; D000954:Antigens, Surface; D001426:Bacterial Proteins; D008562:Membrane Glycoproteins; C055764:S-layer proteins