[HIV infection, fever and cholestasis].
A 35-year-old Swiss woman with AIDS experienced fever, jaundice and cough. Laboratory evaluation revealed signs of an infection and cholestasis. The examination by ultrasound showed thickening of the intra- and extrahepatic bile ducts and gallbladder wall, without dilatation or stones. Endoscopic retrograde cholangiography demonstrated diffuse sclerosing cholangitis like lesions in the biliary tract and confirmed the diagnosis of a HIV related cholangiopathy. The cause was a cytomegalovirus infection as shown by liver biopsy with detection of cytomegalovirus early antigen. The treatment with ganciclovir was of some efficacy with improvement of jaundice.
Giezendanner
S
S
Departement für Innere Medizin, Universitätsspital Zürich.
Zala
G
G
Jost
J
J
Greminger
P
P
Meyenberger
C
C
D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000328:Adult; D015209:Cholangitis, Sclerosing / Q000209:etiology* / Q000382:microbiology; D002779:Cholestasis / Q000209:etiology*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005334:Fever / Q000209:etiology; D015658:HIV Infections / Q000150:complications*; D006801:Humans
HIV-Infektion, Fieber und Cholestase.