Oral management of a patient with a plasminogen activator inhibitor (PAI-1) deficiency: case report.
Plasminogen activator inhibitor-1 (PAI-1) deficiency causes a rare bleeding disorder by allowing excessive fibrinolysis to occur. Knowledge of the specific type and severity of the bleeding disorder is crucial in planning a safe and appropriate treatment sequence in conjunction with a hemophilia team. This article reports the oral management of a 9-year-old female with PAI-1 inhibitor deficiency using tranexamic acid (Cyclokapron).
Tanimura
L K
LK
Indiana University School of Densitry, Indianapolis.
Weddell
J A
JA
McKown
C G
CG
Shapiro
A D
AD
Mulherin
J
J
D000766:Anesthesia, Dental; D002648:Child; D003730:Dental Care for Persons with Disabilities; D003731:Dental Caries / Q000628:therapy; D005260:Female; D005891:Gingivitis / Q000628:therapy; D006801:Humans; D006472:Oral Hemorrhage / Q000517:prevention & control*; D009910:Oral Hygiene; D017395:Plasminogen Activator Inhibitor 1 / Q000172:deficiency*; D014081:Tooth Extraction; D014148:Tranexamic Acid / Q000627:therapeutic use*
D017395:Plasminogen Activator Inhibitor 1; D014148:Tranexamic Acid