Transgenic mice containing a 248-kilobase human beta locus yeast artificial chromosome display proper developmental control of human globin genes.
Peterson
K R
KR
Department of Medicine, University of Washington, Seattle 98195.
Clegg
C H
CH
Huxley
C
C
Josephson
B M
BM
Haugen
H S
HS
Furukawa
T
T
Stamatoyannopoulos
G
G
D000818:Animals; D005075:Biological Evolution; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D005314:Embryonic and Fetal Development / Q000235:genetics; D005786:Gene Expression Regulation; D005914:Globins / Q000235:genetics*; D006128:Growth / Q000235:genetics; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
D012333:RNA, Messenger; D005914:Globins