Prevention of neonatal necrotizing enterocolitis.
There are a number of promising strategies to prevent necrotizing enterocolitis (NEC). These included induction of intestinal maturation with prenatal or postnatal steroids, passive immunization with oral immunoglobulin, modification of enteral feedings, administration of oral antibiotics to decrease bacterial overgrowth while avoiding the development of resistant strains, and acidification of oral fluids to prevent bacterial overgrowth. The initial results need to be confirmed, but it is likely that one or more of these prevention measures will lower the incidence of NEC in the future.
Vasan
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Department of Pediatrics, Rush Medical College, Chicago, Illinois.
Gotoff
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SP
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D004750:Enteral Nutrition; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology / Q000382:microbiology / Q000517:prevention & control*; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007231:Infant, Newborn; D007422:Intestines / Q000382:microbiology; D008895:Milk, Human / Q000276:immunology; D012307:Risk Factors
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents