A cDNA encoding an ADP/ATP carrier from the mosquito Anopheles gambiae.
Two cDNAs are described from Anopheles gambiae that correspond to the ADP/ATP carrier or translocase. The clones are identical except for minor differences in the 5' non-coding region and in the lengths of the poly-A tails. They code for mRNAs of 1261 and 1263 bp and contain one open reading frame of 906 bp. A probe made from the 1263 bp cDNA hybridized to bands of approximately 1260 and 1700 bp on developmental Northern blots. The putative 300 amino acid peptide sequence shows from 53.4-78.5% identity to AAC peptide sequences from a range of organisms from Zea mays to human. Both clones mapped to region 26a on the left arm of chromosome 2 in An. gambiae.
Beard
C B
CB
Malaria Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724.
Crews-Oyen
A E
AE
Kumar
V K
VK
Collins
F H
FH
D000595:Amino Acid Sequence; D000818:Animals; D000852:Anopheles / Q000201:enzymology* / Q000235:genetics*; D001483:Base Sequence; D018076:DNA, Complementary / Q000235:genetics*; D005260:Female; D017344:Genes, Insect; D017403:In Situ Hybridization; D008297:Male; D000226:Mitochondrial ADP, ATP Translocases / Q000235:genetics*; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000235:genetics; D017386:Sequence Homology, Amino Acid
D018076:DNA, Complementary; D012333:RNA, Messenger; D000226:Mitochondrial ADP, ATP Translocases