[Influence of chronic intoxication with phospho-organic insecticide dimethoate on the hemopoietic system in rats].
Toxic effect of insecticide dimethoate applied to 400 rats for two years in concentrations of 2 to 200 mg/kg fodder was investigated. During the last six months of observation the toxic influence of the larger doses of this preparation was manifested by a higher mortality of the animals. Neither disadvantageous influence upon the maturation of each individual haemopoietic series, nor action inducing pathologic proliferation in the haemopoietic system of rats were found.
Jonderko
G
G
IV Katedry i Kliniki Chorób Wewnetrznych Sl. AM w Katowicach.
Polko
M
M
Kita
K
K
Knapek
R
R
Kobes
S
S
Kotyla
P
P
D000818:Animals; D004117:Dimethoate / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006410:Hematopoiesis / Q000187:drug effects*; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D004117:Dimethoate
Badania wpływu przewlekłego zatrucia insektycydem fosforoorganicznym dimetoat na układ krwiotwórczy u szczurów.