title: [The efficacy of a new Russian preparation metiazol in experimental aspiculariasis in mice].
abstract: The efficacy of metiasole, a new Russian analog of albendasole, reproduced at the E. I. Martsinovskiĭ Institute of Medical Parasitology and Tropical Medicine, was studied in mice with Aspiculuris tetraptera invasion. Metiasole efficacy and acute toxicity were comparable to those of embovin and superior to those of medamin. Relationship between the drug efficacy and its doses and number of injections was analyzed.
authors.forename: N I
authors.initials: NI
authors.lastname: Lykova
authors.forename: N L
authors.initials: NL
authors.lastname: Veretennikova
authors.forename: M N
authors.initials: MN
authors.lastname: Lebedeva
authors.forename: E V
authors.initials: EV
authors.lastname: Timonov
authors.forename: G N
authors.initials: GN
authors.lastname: D'iachenko
mesh_terms: D015766:Albendazole / Q000627:therapeutic use* / Q000633:toxicity; D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use / Q000633:toxicity; D001562:Benzimidazoles / Q000627:therapeutic use / Q000633:toxicity; D002219:Carbamates; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D007928:Lethal Dose 50; D051379:Mice; D010123:Oxyuriasis / Q000188:drug therapy*; D011716:Pyrantel Pamoate / Q000627:therapeutic use / Q000633:toxicity
chemical_list: D000969:Antinematodal Agents; D001562:Benzimidazoles; D002219:Carbamates; D011716:Pyrantel Pamoate; D015766:Albendazole; C006698:carbendazim
vernacular_title: Izuchenie éffektivnosti novogo otechestvennogo preparata metiazola pri éksperimental'nom aspikuluroze u mysheĭ.