title: Pulmonary function tests before and after laparoscopic cholecystectomy.
abstract: Pulmonary function tests were performed in 22 patients undergoing laparoscopic cholecystectomy. Measurements were made before, 24 h after, and 6 weeks after operation (12 patients). At 24 h postoperatively there were significant decreases in forced expiratory volume in 1 s, vital capacity, functional residual capacity and total lung capacity to 75% (p < 0.001), 73% (p < 0.001), 92% (p = 0.002) and 83% (p < 0.001) of pre-operative values respectively. Inspiratory and expiratory mouth pressures decreased to 66% (p < 0.001) and 63% (p < 0.001) of the pre-operative pressures respectively. There was a reduction in PaO2 (p < 0.01) and an increase in alveolar-arterial gradient (p < 0.001) but no change in PaCO2 at 24 h. The pulmonary function tests measured in the patients who returned after 6 weeks had returned to pre-operative values.
authors.affiliation: Department of Anaesthetics, Western General Hospital, Edinburgh.
authors.forename: J A
authors.initials: JA
authors.lastname: Freeman
authors.forename: I R
authors.initials: IR
authors.lastname: Armstrong
mesh_terms: D002245:Carbon Dioxide / Q000097:blood; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D005652:Functional Residual Capacity / Q000502:physiology; D006801:Humans; D008168:Lung / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011446:Prospective Studies; D012129:Respiratory Function Tests; D013997:Time Factors; D014109:Total Lung Capacity / Q000502:physiology; D014797:Vital Capacity / Q000502:physiology
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen