Radiotracer measurement of ureteric blood flow.
This paper describes a novel technique using the blood flow tracer C14-iodoantipyrine to measure ureteric blood flow in anesthetized Sprague-Dawley rats. The ureters were divided into five equal segments, and the blood flow was measured using a modification of the Fick principle. There was a gradient down the ureter with a significant difference between upper (159 ml./100 gm./min.) and lower (83 ml./100 gm./min.) ureteric segmental blood flows. This technique may allow the role of ureteric ischemia to be investigated in a variety of disease states.
Mooney
E F
EF
Surgical Professorial Unit, Mater Misericordiae Hospital, Dublin, Ireland.
Geraghty
J G
JG
O'Connell
M
M
Kent
P
P
Angerson
W
W
Quereshi
A
A
Sarazen
A
A
Fitzpatrick
J M
JM
D000818:Animals; D000983:Antipyrine / Q000031:analogs & derivatives; D002250:Carbon Radioisotopes; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D014513:Ureter / Q000098:blood supply*
D002250:Carbon Radioisotopes; D000983:Antipyrine; C008135:iodoantipyrine