title: Heteronymous recurrent inhibition from gastrocnemius muscle to soleus motoneurones in humans.
abstract: Presence of heteronymous recurrent inhibition in motoneurones (Mns) innervating the soleus muscle (Sol) was investigated following electrical stimulation of the nerve of gastrocnemius medialis muscle (GM). Sub-threshold electrical stimulation for alpha Mns produced short-lasting inhibition of the Sol, reflecting non-reciprocal group I inhibition. After increasing the intensity of stimulation above the motor threshold, a short-latency, long-lasting inhibition appeared superimposed on the group I inhibition. Its amount increased with the size of the conditioning motor response and after acute administration of L-acetylcarnitine. It is concluded that this long-lasting inhibition of the Sol Mns is due to the heteronymous activity of the GM-coupled Renshaw cells.
authors.affiliation: Laboratorio di Neurofisiologia dell'Istituto di Scienze Neurologiche, Toro, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Rossi
authors.forename: A
authors.initials: A
authors.lastname: Zalaffi
authors.forename: B
authors.initials: B
authors.lastname: Decchi
mesh_terms: D000108:Acetylcarnitine / Q000494:pharmacology; D000328:Adult; D004558:Electric Stimulation; D006181:H-Reflex / Q000187:drug effects / Q000502:physiology; D006801:Humans; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D009132:Muscles / Q000187:drug effects / Q000294:innervation / Q000502:physiology*; D009412:Nerve Fibers / Q000187:drug effects / Q000502:physiology
chemical_list: D000108:Acetylcarnitine