[Hypertensive activity of blood plasma of WKY rats with a calcium deficiency in drinking water].
The effects of low (8.0 mg/l) and normal (80 mg/l) Ca2+ water diets on systolic blood pressure (SBP) and hypertensive plasma activity were studied. At the end of the 16-week experimental period SBP in the low-Ca2+ group of animals was higher than in the control group after the water treatment: 161 sigma 9 and 120 +/- 4 mm Hg respectively. Significant hypertensive plasma activity of the Ca(2+)-deficient rats was noted in all cases. WKY plasma of the rats of normal-Ca2+ group had no significant effect on SBP. Water correction according to the physiologically recommended levels of calcium can prevent the development of arterial hypertension and occurrence of hypertensive plasma activity.
Churina
S K
SK
Eschanova
G T
GT
Kliueva
N Z
NZ
Ryzhov
D B
DB
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002136:Calcium, Dietary / Q000008:administration & dosage*; D006973:Hypertension / Q000097:blood*; D008297:Male; D051381:Rats; D011921:Rats, Inbred WKY; D014881:Water Supply
D002136:Calcium, Dietary
Gipertenzivnaia aktivnost' plazmy krovi krys linii WKY, soderzhavshchikhsia v usloviiakh defitsita kal'tsiia v pit'evoĭ vode.