Maternal serum free beta-human chorionic gonadotrophin levels in twin pregnancies: implications for screening for Down's syndrome.
Free beta-human chorionic gonadotrophin values are, on average, 1.90 times greater in twin pregnancies than in singleton pregnancies [95 per cent confidence interval (CI) 1.69-2.13]. This information can be used in screening for Down's syndrome, so that twin pregnancies can be interpreted in addition to singleton pregnancies.
Wald
N J
NJ
Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, St Bartholomew's Hospital Medical College, London, U.K.
Densem
J W
JW
D006063:Chorionic Gonadotropin / Q000097:blood*; D004200:Diseases in Twins / Q000175:diagnosis*; D004314:Down Syndrome / Q000097:blood / Q000175:diagnosis*; D005260:Female; D005819:Genetic Markers; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy
D006063:Chorionic Gonadotropin; D005819:Genetic Markers