title: [Experiences with mitomycin C].
abstract: BACKGROUND
  Recently, encouraging results with the use of Mitomycin C in trabeculectomy have been reported.
  
  
  METHODS
  We used Mitomycin C (0.028%) during trabeculectomy in 72 eyes of 68 patients. Forty-one eyes have already been controlled during 6 months and 19 eyes during 9 months after the surgery.
  
  
  RESULTS
  The mean intraocular pressure after 6 and 9 months was respectively 13 +/- 8 mm Hg and 13 +/- 10 mm Hg. The difference between these results and the preoperative values (27 +/- 9 mm Hg) were statistically significant after 6 and 9 months (p < 0.001). Despite frequent choroidal detachments (20 eyes), the visual acuity recovered during the follow-up to the preoperative values.
  
  
  CONCLUSIONS
  In patients with uncertain prognosis for the intraocular pressure after trabeculectomy, the intraoperative application of Mitomycin C seems to improve considerably the operative success rate.
authors.affiliation: Universitäts-Augenklinik Basel.
authors.forename: A Z
authors.initials: AZ
authors.lastname: Gaspar
authors.forename: S
authors.initials: S
authors.lastname: Orgül
authors.forename: J
authors.initials: J
authors.lastname: Flammer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage* / Q000009:adverse effects; D009883:Ophthalmic Solutions; D014130:Trabeculectomy / Q000379:methods*; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D009883:Ophthalmic Solutions; D016685:Mitomycin
vernacular_title: Erfahrungen mit Mitomycin C.