title: Incidental finding of a hepatic lesion: differential diagnostic problems for fibrolamellar hepatic carcinoma.
abstract: We report the case of a 39-yr-old female with a liver lesion that was incidentally detected by ultrasound. Examination of biopsy specimens revealed focal nodular hyperplasia. A metastatic tumor in the right os ilium developed in the following weeks and showed specific uptake of 99mTc-hepatic 2,6-dimethyliminodiacetic acid (HIDA), suggesting metastasis from a differentiated hepatocellular carcinoma. The final pathologic diagnosis was multifocal, solid and glandular hepatocellular carcinoma, partly differentiated as fibrolamellar carcinoma, and an osseous metastasis from the differentiated hepatocellular carcinoma.
authors.affiliation: Weyer Institute for Nuclear Medicine Diagnostic, Freiburg, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Reuland
authors.forename: K P
authors.initials: KP
authors.lastname: Aicher
authors.forename: H J
authors.initials: HJ
authors.lastname: Brambs
authors.forename: G
authors.initials: G
authors.lastname: Enderle
authors.forename: U
authors.initials: U
authors.lastname: Feine
authors.forename: H V
authors.initials: HV
authors.lastname: Gärtner
authors.forename: P
authors.initials: P
authors.lastname: Weber
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D003937:Diagnosis, Differential; D004164:Diphosphonates; D005260:Female; D006801:Humans; D007085:Ilium / Q000000981:diagnostic imaging*; D007098:Imino Acids; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008207:Lymphatic Metastasis; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019780:Technetium Tc 99m Lidofenin
chemical_list: D004164:Diphosphonates; D007098:Imino Acids; D015609:Organotechnetium Compounds; C033905:technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid; D019780:Technetium Tc 99m Lidofenin