Genetics and molecular biology of mouse pigmentation.
The formation of mouse coat color is a relatively complex developmental process that is affected by a large number of mutations, both naturally occurring and induced. The cloning of the genes in which these mutations occur and the elucidation of the mechanisms by which these mutations disrupt the normal pigmentation pattern is leading to an understanding of the way interactions between gene products lead to a final phenotype.
Jackson
I J
IJ
MRC Human Genetics Unit, Western General Hospital, Edinburgh, U.K.
Budd
P
P
Horn
J M
JM
Johnson
R
R
Raymond
S
S
Steel
K
K
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D006801:Humans; D019746:Intramolecular Oxidoreductases; D007535:Isomerases / Q000235:genetics*; D008544:Melanocytes / Q000502:physiology; D008562:Membrane Glycoproteins; D051379:Mice; D008969:Molecular Sequence Data; D014442:Monophenol Monooxygenase / Q000235:genetics*; D010088:Oxidoreductases; D010858:Pigmentation / Q000235:genetics*; D011506:Proteins / Q000235:genetics*
D008562:Membrane Glycoproteins; D011506:Proteins; D010088:Oxidoreductases; C489799:TYRP1 protein, human; C079621:Tyrp1 protein, mouse; C064056:tyrosinase-related protein-1; D014442:Monophenol Monooxygenase; D007535:Isomerases; D019746:Intramolecular Oxidoreductases; C042501:dopachrome isomerase