title: Successful treatment of early infective endocarditis and mediastinitis in a heart transplant recipient.
abstract: We report a case of bacterial endocarditis in a heart transplant recipient that was diagnosed 6 weeks after operation when a transesophageal echocardiogram revealed vegetations on both sides of the atrial septum. The patient also had postoperative mediastinitis and pericarditis. He underwent two mediastinal explorations, pericardiectomy, and 22 weeks of antibiotics and is free of infection 1 year after transplantation. We presume that the source of infection was contamination of the donor heart by the donor's right lung, which was harvested en bloc with the heart.
authors.affiliation: University of Arizona Health Sciences Center, Section of Cardiology and Cardiothoracic Surgery, Tucson.
authors.forename: B
authors.initials: B
authors.lastname: Toporoff
authors.forename: L J
authors.initials: LJ
authors.lastname: Rosado
authors.forename: C P
authors.initials: CP
authors.lastname: Appleton
authors.forename: G K
authors.initials: GK
authors.lastname: Sethi
authors.forename: J G
authors.initials: JG
authors.lastname: Copeland
mesh_terms: D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D016972:Enterobacter cloacae; D004756:Enterobacteriaceae Infections / Q000188:drug therapy; D016027:Heart Transplantation; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D007778:Lactobacillus; D008297:Male; D008480:Mediastinitis / Q000188:drug therapy* / Q000382:microbiology; D008875:Middle Aged; D010493:Pericarditis / Q000188:drug therapy / Q000382:microbiology; D014031:Tobramycin / Q000627:therapeutic use
chemical_list: D015378:Imipenem; D014031:Tobramycin