title: A 24-h inpatient detoxification treatment for heroin addicts: a preliminary investigation.
abstract: The present study describes a detoxification method which takes only 4 h to complete. Eleven polydrug users addicted to opiates were detoxified 12 h after their last dose of heroin, in an intensive care unit. The detoxification was carried out using naltrexone, after sedation with midazolan. After detoxification (12 h) patients were discharged without withdrawal symptoms. This procedure offers a rapid detoxification procedure which seems to be widely accepted by the addicts themselves.
authors.affiliation: CITA Centro de Investigación y Tratamiento Psicológicos, Seville, Spain.
authors.forename: J J
authors.initials: JJ
authors.lastname: Legarda
authors.forename: M
authors.initials: M
authors.lastname: Gossop
mesh_terms: D000284:Administration, Oral; D000328:Adult; D016292:Procedural Sedation; D004334:Drug Administration Schedule; D005500:Follow-Up Studies; D016316:Guanfacine / Q000008:administration & dosage; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D007362:Intensive Care Units; D007902:Length of Stay; D008297:Male; D008874:Midazolam; D009271:Naltrexone / Q000008:administration & dosage* / Q000009:adverse effects; D009460:Neurologic Examination / Q000187:drug effects; D010343:Patient Admission; D011292:Premedication; D015813:Substance Abuse Detection; D013375:Substance Withdrawal Syndrome / Q000209:etiology
chemical_list: D016316:Guanfacine; D009271:Naltrexone; D008874:Midazolam