Isolated fetal bilateral radial ray reduction associated with valproic acid usage.
The authors describe the first case of an isolated bilateral radial ray reduction occurring in a fetus exposed in utero to valproic acid; the diagnosis was made by ultrasound during the second trimester. This case of an isolated radial ray reduction associated with valproic acid use in pregnancy is a reminder for sonographers to carefully examine not only the cardiac and neurologic system, but also the extremities, when a fetus is exposed in utero to valproic acid.
Langer
B
B
Service de Gynécologie-Obstétrique II, Hôpital de Hautepierre, Université-Hôpital de Strasbourg, France.
Haddad
J
J
Gasser
B
B
Maubert
M
M
Schlaeder
G
G
D000014:Abnormalities, Drug-Induced; D000328:Adult; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications; D011884:Radius / Q000002:abnormalities*; D016216:Ultrasonography, Prenatal; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D014635:Valproic Acid