title: [New experimental oncologic studies on prevention of bladder cancer].
abstract: Experimental data connected with prophylaxis of vesical cancer are reviewed. The following prophylactic measures are discussed: influence on metabolism of carcinogens and inactivation of metabolites; forced clearance of carcinogenic metabolites; carcinogenesis promoters arrest. Specific inhibition of beta-glucuronidase in urine and forced diuresis appeared to be extremely effective.
authors.forename: G B
authors.initials: GB
authors.lastname: Pliss
mesh_terms: D000818:Animals; D002752:Chlorthalidone / Q000494:pharmacology*; D004231:Diuresis / Q000187:drug effects; D005665:Furosemide / Q000494:pharmacology*; D005966:Glucuronidase / Q000037:antagonists & inhibitors*; D051381:Rats; D012977:Sodium Nitrite / Q000009:adverse effects; D018038:Sodium Selenite / Q000494:pharmacology*; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced / Q000503:physiopathology / Q000517:prevention & control*
chemical_list: D005665:Furosemide; D005966:Glucuronidase; D018038:Sodium Selenite; D012977:Sodium Nitrite; D002752:Chlorthalidone
vernacular_title: Profilaktika raka mochevogo puzyria v svete éksperimentalńo-onkologicheskikh issledovaniĭ.