Benign cephalic histiocytosis: case report and literature review.
A 3-year-old boy had maculopapules on his face and neck since age 6 months. These were yellow-brown, asymptomatic, and clinically similar to flat warts. Histopathologic study revealed a fibrohistiocytic infiltrate in the superficial dermis. Ultrastructurally, comma-shaped bodies, desmosome-like junctions, and coated vesicles were seen; there were no lipid droplets or Birbeck granules. With these data, a diagnosis of benign cephalic histiocytosis was made. Twenty-five cases are reported in the literature: 17 males and 8 females (male:female ratio 2:1). Sixteen patients had lesions on parts of the body other than the head, neck, and shoulders.
Peña-Penabad
C
C
Department of Dermatology, University Hospital, Salamanca, Spain.
Unamuno
P
P
Garcia-Silva
J
J
Ludeña
M D
MD
Armijo
M
M
D002675:Child, Preschool; D006257:Head; D015616:Histiocytosis, Non-Langerhans-Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000473:pathology / Q000648:ultrastructure; D012871:Skin Diseases / Q000473:pathology*