title: [Transferability of results in hematologic determinations].
abstract: OBJECTIVE
  To evaluate inaccuracy of the results attained in several Servei Catalá de la Salut laboratories in order to assess if quality purposes are accomplished and results are transferable between them.
  
  
  METHODS
  Two types of haematological analysers are used: those based upon volumetric measurements and those using light dispersion for particle counting. Inaccuracy was ascertained in accordance to the inter-laboratory quality control programme. The inter-series study was performed with commercial control material in each laboratory with their own data, the monthly coefficient of variation being found, and the mean of the CV of 12 months was then calculated. Intra-series inaccuracy with commercial control material was assessed in each laboratory three times a day for 10 days, and the inaccuracy with fresh patient blood was examined daily in triplicate. The analytical inaccuracy attained in patient samples was also compared with that attained with stabilized control materials.
  
  
  RESULTS
  The inaccuracy quality limits were exceeded in the haematological constituents under study. Quality objectives were accomplished in the inter-series inaccuracy study for red cell count, white cell count, MCV, granulocytes and lymphocytes. Repeat fresh patient-blood assays can be used to assess intra-series inaccuracy for red and white cell counts, but not for platelet count.
  
  
  CONCLUSIONS
  Inaccuracy of the blood constituents studied is not transferable. Inaccuracy for the commonest haematological values is transferable between laboratories. Intra-series inaccuracy for red and white cell counts can be assessed by repeated use of fresh patient-blood when control material is not available. Patient samples are not advisable as a control of the white cell differential count for intra-series inaccuracy studies in those systems using volumetric principles.
authors.affiliation: Servicio Análisis Clínicos, C.A.P. Cornellá, Bellaterra, Barcelona.
authors.forename: V
authors.initials: V
authors.lastname: Alvarez
authors.forename: A
authors.initials: A
authors.lastname: Hernández
authors.forename: C V
authors.initials: CV
authors.lastname: Jiménez
authors.forename: J
authors.initials: J
authors.lastname: Minchinela
authors.forename: C
authors.initials: C
authors.lastname: Perich
authors.forename: C
authors.initials: C
authors.lastname: Ricós
authors.forename: M
authors.initials: M
authors.lastname: Simón
mesh_terms: D001772:Blood Cell Count / Q000295:instrumentation; D006403:Hematologic Tests / Q000295:instrumentation / Q000592:standards; D006801:Humans; D007755:Laboratories, Hospital; D011786:Quality Control; D012015:Reference Standards; D015203:Reproducibility of Results
vernacular_title: Transferibilidad de los resultados en determinaciones hematológicas.