Gold induced colitis and hepatic toxicity in a patients with rheumatoid arthritis.
We describe a case of severe colitis in a 40-year-old woman early in the course of intramuscular gold therapy for rheumatoid arthritis. Despite prompt withdrawal of gold, our patient required emergency laparotomy and bowel decompression. Incidental cholestatic hepatotoxicity, a further rare adverse reaction to gold, was also noted in our patient.
Nisar
M
M
Sheffield Centre for Rheumatic Diseases, Nether Edge Hospital, England.
Winfield
J
J
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002779:Cholestasis / Q000139:chemically induced*; D003092:Colitis / Q000139:chemically induced*; D005260:Female; D006052:Gold Sodium Thiomalate / Q000009:adverse effects*; D006801:Humans
D006052:Gold Sodium Thiomalate