title: [Diagnostic value and interpretation of imaging bone densitometry based on quantitative CT].
abstract: Quantitative CT of the axial skeleton (aQCT) may serve as an example of the evaluation and interpretation of bone densitometric data as it is the only state-of-the-art technique with valid longitudinal observations. The value of bone density measurements in interindividual cross sections refers to a grading derived from a representative reference population and provides an evaluation of fracture risk. The presence and rate of any bone loss can only be evaluated in an intraindividual longitudinal follow-up. Adequate follow-up for trabecular bone requires at least 3 to 5 years intervals to discriminate between different loss rates. Bone losses induced by steroid therapy or immobilisation may have faster kinetics apparent within months; bone density increase due to hormone substitution may be significant after one to two years. Morphological data allow critical evaluation of the quantitative measurements, eliminating false values and differentiating between rarefying and destructive osteopenia.
authors.affiliation: Fachbereich Bildgebende Diagnostik, Deutsche Klinik für Diagnostik Wiesbaden.
authors.forename: G
authors.initials: G
authors.lastname: Reuther
authors.forename: M
authors.initials: M
authors.lastname: Dören
authors.forename: P E
authors.initials: PE
authors.lastname: Peters
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D001847:Bone Diseases / Q000000981:diagnostic imaging*; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008593:Menopause; D008875:Middle Aged; D010018:Osteomalacia / Q000000981:diagnostic imaging; D010024:Osteoporosis / Q000000981:diagnostic imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods
vernacular_title: Aussagefähigkeit und Interpretation der bildgebenden Osteodensitometrie am Beispiel der quantitativen CT.