[Bilateral conjunctivo-palpebral tumor in an immunocompetent man cause by human papilloma virus].
A 46-year-old white male patient in good general health presented with a bilateral conjunctival and eyelid tumor and a wart at the tip of the fourth right finger. Impression cytology showed dysplasic cells with loss of cohesion and up to 4 nucleoli per nucleus. The excisional biopsy of the conjunctiva revealed a dysplasic epithelial tissue that allowed the diagnosis of papilloma with parts of conjunctival intraepithelial neoplasia (CIN). Papilloma has been associated with Human Papillomavirus (HPV). The molecular hybridization analysis using PCR revealed that HPV was present in the eye tumor and in the wart, but the viral type was not the same. Treatment of the eye tumor with excision and low temperature cryocoagulation was successful.
Tritten
J J
JJ
Hôpital Ophtalmique Jules Gonin, Lausanne.
Beati
D
D
Sahli
R
R
Uffer
S
S
D001706:Biopsy; D003228:Conjunctiva / Q000473:pathology; D003230:Conjunctival Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005143:Eyelids / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000473:pathology; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000175:diagnosis* / Q000473:pathology
Tumeur conjonctivo-palpébrale bilatérale chez un homme immuno-compétent due au virus du papilloma humain (HPV).