title: Methodological issues in validating decision-support systems for insulin dosage adjustment.
abstract: Safety and reliability of advice from new computer systems should be confirmed before embarking on prospective hospital trials. This process of preliminary testing is termed 'validation'. Though it forms a fundamental stage in system development, few standards exist for choosing and implementing tests. In the present paper, a validation methodology is developed in the domain of diabetes and intended for general use in chronic health management. It is based on a peer review protocol and incorporates empirical measures indicating: applicability of results to the real environment; variation among doctors; comparisons between doctors' and computer advice; and relative merits of different computer algorithms.
authors.affiliation: Department of Systems Science, City University, London, UK.
authors.forename: H J
authors.initials: HJ
authors.lastname: Leicester
authors.forename: A V
authors.initials: AV
authors.lastname: Roudsari
authors.forename: E D
authors.initials: ED
authors.lastname: Lehmann
authors.forename: E R
authors.initials: ER
authors.lastname: Carson
mesh_terms: D000465:Algorithms; D001786:Blood Glucose / Q000378:metabolism; D003661:Decision Support Techniques; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000523:psychology; D007328:Insulin / Q000008:administration & dosage* / Q000627:therapeutic use; D008019:Life Style; D017712:Peer Review, Research; D012986:Software Validation
chemical_list: D001786:Blood Glucose; D007328:Insulin