title: Thoracotomy in the management of metastatic soft-tissue sarcomas in adults.
abstract: The multidisciplinary management of metastatic soft-tissue sarcomas in adults is capable of salvaging approximately half of the afflicted patients. This management includes preoperative chemotherapy for three months, thoracic surgery, continued chemotherapy, and the use of intrapleural mitoxantrone for once-present malignant pleural effusions or suspected pleural seeding of tumor. Thus, there is a definite role for the inclusion of thoracic surgery in the management of patients with soft-tissue sarcomas in whom pulmonary metastases develop.
authors.affiliation: Cedars-Sinai Comprehensive Cancer Center, Los Angeles, California.
authors.forename: G
authors.initials: G
authors.lastname: Rosen
authors.forename: E C
authors.initials: EC
authors.lastname: Holmes
authors.forename: C A
authors.initials: CA
authors.lastname: Forscher
authors.forename: S
authors.initials: S
authors.lastname: Lowenbraun
authors.forename: F R
authors.initials: FR
authors.lastname: Eilber
authors.forename: J J
authors.initials: JJ
authors.lastname: Eckardt
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D008875:Middle Aged; D011182:Postoperative Care; D011300:Preoperative Care; D012074:Remission Induction; D012509:Sarcoma / Q000145:classification / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D012983:Soft Tissue Neoplasms / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D015996:Survival Rate; D013908:Thoracotomy