title: [Sodium hypochlorite in the detoxification therapy of postresuscitation states].
abstract: The experiments on dogs recovered after a 10-min clinical death of acute blood loss have shown possible effective use of 300-500 mg/l sodium hypochlorite solution at a dose of 7-10 ml/kg for detoxication in the early postresuscitation period. A significant reduction in the level of toxemia within 3 hours of postresuscitation period, as compared to the control, promotes an increase in the percent of the animals survived and a more complete recovery of the neurological status. It has been shown in vitro than detoxication of lymph in septic patients was more effective using electrochemical oxidation, as compared to sorption on a carbon CKH sorbent, with lymph protein loss being significantly less. The technique of electrochemical liquid oxidation can be recommended as an alternative detoxicating technique in critical conditions.
authors.forename: I O
authors.initials: IO
authors.lastname: Zaks
authors.forename: I F
authors.initials: IF
authors.lastname: Bogoiavlenskiĭ
authors.forename: A K
authors.initials: AK
authors.lastname: Martynov
mesh_terms: D000208:Acute Disease; D000818:Animals; D003643:Death; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D004731:Endotoxins / Q000097:blood; D006470:Hemorrhage / Q000097:blood / Q000628:therapy; D006801:Humans; D066298:In Vitro Techniques; D008196:Lymph / Q000378:metabolism; D012151:Resuscitation; D012973:Sodium Hypochlorite / Q000008:administration & dosage*; D016060:Sorption Detoxification / Q000379:methods*; D013997:Time Factors; D014115:Toxemia / Q000378:metabolism / Q000628:therapy
chemical_list: D004731:Endotoxins; D012973:Sodium Hypochlorite
vernacular_title: Gipokhlorit natriia v detoksikatsionnoĭ terapii postreanimatsionnykh sostoianiĭ.