title: Percutaneous nephrostomy in patients with advanced or recurrent cervical cancer.
abstract: Thirteen percutaneous nephrostomies were performed in 10 patients with advanced (no = 4) (group A) or recurrent (no = 6) (group B) cervical cancer. Urinary diversion was unilateral in 7 patients and bilateral in 3 patients. The catheter was kept in place for 4 months in mean (range: 1-7 months). A normalization of renal function was achieved in 4 out of 4 patients of group A, and in 3 out of 6 patients of group B. Of the 4 patients of group A, who afterwards underwent antineoplastic integrated treatments, 2 patients are currently alive with no evidence of disease after 48 and 20 months from the diagnosis, respectively, while the other 2 died of disease after 10 and 14 months, respectively. Of the 6 patients of group B, 5 patients died within 7 months, while another patient is currently undergoing chemotherapy. The present data seem to confirm that percutaneous nephrostomy can be of clinical benefit for patients with advanced cervical cancer, having a chance of prolonged palliation or cure. Conversely, this technique seems to be of little use for patients with recurrent disease, for whom no effective salvage therapy is generally available.
authors.affiliation: Department of Gynecology and Obstetrics, University of Pisa.
authors.forename: A
authors.initials: A
authors.lastname: Gadducci
authors.forename: A
authors.initials: A
authors.lastname: Madrigali
authors.forename: V
authors.initials: V
authors.lastname: Facchini
authors.forename: P
authors.initials: P
authors.lastname: Fioretti
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology / Q000601:surgery*; D007668:Kidney / Q000503:physiopathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D009403:Nephrostomy, Percutaneous; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000503:physiopathology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents