title: Current status of screening for lung cancer.
abstract: Three parallel studies on screening for lung cancer, supported by the National Cancer Institute, were carried out by the Mayo Clinic, Johns Hopkins Medical Institutions, and Memorial Sloan-Kettering Center from 1971 to 1982. No significant mortality improvement was established that could be attributed to cytologic screening examinations. Many stage I lung cancers were detected by radiographic screening, with excellent changes for long-term survival. Patients with stage I cancers who were operated on had significantly better survival rates than those who failed to undergo surgery. Statistical modeling, however, indicates that long-term annual screening of a high-risk population would decrease lung cancer mortality by no more than 18%.
authors.affiliation: Mathematical Sciences Department, T.J. Watson Research Center, Yorktown Heights, New York.
authors.forename: B J
authors.initials: BJ
authors.lastname: Flehinger
authors.forename: M R
authors.initials: MR
authors.lastname: Melamed
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000401:mortality / Q000517:prevention & control* / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000401:mortality / Q000517:prevention & control* / Q000601:surgery; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000401:mortality / Q000517:prevention & control* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000401:mortality / Q000517:prevention & control* / Q000601:surgery; D002985:Clinical Protocols; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000517:prevention & control* / Q000601:surgery; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D008962:Models, Theoretical; D009367:Neoplasm Staging; D015995:Prevalence; D011379:Prognosis; D012907:Smoking; D015996:Survival Rate; D013997:Time Factors; D014481:United States