Lymph node metastasis in medulloblastoma.
A 14-year-old boy was diagnosed as having a medulloblastoma in the posterior fossa. Radiation therapy was given and the patient made a good recovery. Three months later he presented with supraclavicular lymph node metastasis, in the absence of other foci of metastases. He was treated with 60Co and the metastasis decreased. Two months later a bone scan and bone marrow aspiration showed bone metastasis. He was started on chemotherapy. The different possible mechanisms of metastasis are discussed.
Sheikh
B
B
Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Kanaan
I
I
D000293:Adolescent; D001859:Bone Neoplasms / Q000556:secondary; D001932:Brain Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003388:Cranial Fossa, Posterior / Q000473:pathology* / Q000528:radiation effects / Q000601:surgery; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology* / Q000528:radiation effects / Q000601:surgery; D008297:Male; D008527:Medulloblastoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D009362:Neoplasm Metastasis; D012446:Sacroiliac Joint / Q000473:pathology