title: Salivary gland neoplasms in children: a 10-year survey at the Children's Hospital of Philadelphia.
abstract: Fifteen salivary gland tumors were treated at The Children's Hospital of Philadelphia between 1982 and 1991. Eight of these lesions were malignant and 7 were benign. All of the benign tumors were pleomorphic adenomas. For these, superficial parotidectomy or excision of the submandibular gland was the treatment of choice. One child had recurrence 2 years after her initial surgery. Among the malignant lesions, mucoepidermoid carcinoma was diagnosed in 5 children, and acinic cell carcinoma in 3. Six malignant tumors involved the parotid gland, while 2 originated in the submandibular salivary gland. Superficial or total parotidectomy, or excision of the submandibular gland was performed, according to the nature and the location of the lesion. The facial nerve was sacrificed in one patient because of extensive involvement of the nerve. A 2-year survival rate of 100% was achieved, and all the patients were free of disease at the end of the follow-up period. Successful management of salivary gland lesions in children requires a high index of suspicion of possible malignancy and complete surgical removal as the initial treatment. Radiation therapy is recommended in the management of those patients with microscopic residual tumor and/or nodal involvement.
authors.affiliation: Assaf Harofeh Medical Center, Zerifin, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Kessler
authors.forename: S D
authors.initials: SD
authors.lastname: Handler
mesh_terms: D008949:Adenoma, Pleomorphic / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D018267:Carcinoma, Acinar Cell / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D018277:Carcinoma, Mucoepidermoid / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012468:Salivary Gland Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery