title: [The human herpesvirus type 6 (HHV-6) and its spread in Russia].
abstract: This is the first presentation of information on the circulation of human herpes virus type 6 (HHV-6) in the population of the mid-European part of this country. The results of the study indicate that HHV-6 is widely spread both among apparently normal people and among patients with different pathologies. The studies using immunofluorescence test showed that the percentage of HHV-6-infected subjects was practically similar among blood donors, patients with nasopharyngeal cancer, rheumatoid arthritis, hemophilia, and patients with transplanted kidney, varying from 34% to 49%. A significantly higher per cent (66%) and higher antibody titres to HHV-6 were detected in sera from patients with hemoblastoses. A high level of HHV-6 infection among patients with hemoblastoses was also confirmed by the results of immunoblotting showing a wider spectrum and higher intensity of the detectable proteins. It should be noted that the amounts of virus-specific proteins detectable by some sera showed individual variations indicating different levels of expression of viral proteins in different individuals.
authors.forename: V N
authors.initials: VN
authors.lastname: Stepina
authors.forename: T A
authors.initials: TA
authors.lastname: Afanas'eva
authors.forename: V V
authors.initials: VV
authors.lastname: Evtushenko
authors.forename: A V
authors.initials: AV
authors.lastname: Pivnik
authors.forename: M M
authors.initials: MM
authors.lastname: Riashentsev
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Andreev
authors.forename: Kh
authors.initials: Kh
authors.lastname: Kistoglu
authors.forename: V E
authors.initials: VE
authors.lastname: Gurtsevich
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D000918:Antibody Specificity; D001172:Arthritis, Rheumatoid / Q000276:immunology; D001782:Blood Donors / Q000706:statistics & numerical data; D006467:Hemophilia A / Q000276:immunology; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology; D015654:Herpesvirus 6, Human / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology; D007938:Leukemia / Q000276:immunology; D009303:Nasopharyngeal Neoplasms / Q000276:immunology; D015995:Prevalence; D012426:Russia / Q000453:epidemiology; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral
vernacular_title: Virus gerpesa cheloveka tipa 6 (HHV-6) i ego rasprostranenie v strane.