Malignant fibrous histiocytoma of the spleen and chronic myelogenous leukemia. A case report.
We report a rare case of a patient with an intrasplenic malignant fibrous histiocytoma (MFH) and chronic myelogenous leukemia. The neoplasms were synchronous in their onset and evolution. The peculiarity of the primary site of the MFH, the genetic implications of multiple primary tumors in a single patient, and the controversy about the cell precursors of MFH are briefly outlined.
Bonilla
F
F
Section of Medical Oncology, Clinica Puerta de Hierro, Madrid, Spain.
Provencio
M
M
Fernandez
E
E
España
P
P
D000328:Adult; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000209:etiology / Q000473:pathology*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000209:etiology / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000209:etiology / Q000473:pathology*; D013160:Splenic Neoplasms / Q000209:etiology / Q000473:pathology*