Cutaneous manifestation of sarcoidosis (Boeck) with severe osseous destruction of the midface. A case report.
A 16-year-old Caucasian girl presented with brownish red plaques and papules beneath the right eye, and a right side open bite. The cutaneous changes had occurred more than 13 years previously. Radiological evaluation of the chest demonstrated bilateral hilar lymphadenopathy. Kveim-Siltzbach test of the skin was positive. Histological examination of several biopsy specimens taken from skin, oral mucosa and anterior wall of the right paranasal sinus revealed the diagnosis of sarcoidosis (Boeck). Therefore steroid therapy was initiated and the patient was placed on 40 mg prednisone daily. Under this treatment the sarcoidosis manifestations improved generally, and the prednisone dose was subsequently reduced.
Klesper
B
B
Clinic for Maxillo-Facial and Oral Surgery, Eppendorf University Hospital, Germany.
Schmelzle
R
R
Donath
K
K
D000293:Adolescent; D003937:Diagnosis, Differential; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology; D006801:Humans; D008439:Maxillary Diseases / Q000473:pathology*; D012507:Sarcoidosis / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*