title: Failure of methotrexate treatment for term placenta percreta.
abstract: Placenta percreta is a severe condition associated with maternal morbidity and mortality even when surgery is performed electively. Methotrexate has been suggested as a possible treatment modality for adherent placenta to avoid catastrophic surgery. The purpose of this report is to present a case where the placenta was left in situ to avoid cystectomy at the time of cesarean section, with subsequent failure of treatment with methotrexate.
authors.affiliation: Division of Maternal-Fetal Medicine, University of Rochester, NY.
authors.forename: R
authors.initials: R
authors.lastname: Jaffe
authors.forename: B
authors.initials: B
authors.lastname: DuBeshter
authors.forename: D M
authors.initials: DM
authors.lastname: Sherer
authors.forename: E A
authors.initials: EA
authors.lastname: Thompson
authors.forename: J R
authors.initials: JR
authors.lastname: Woods
mesh_terms: D000328:Adult; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D008727:Methotrexate / Q000627:therapeutic use*; D010921:Placenta Accreta / Q000188:drug therapy*; D011247:Pregnancy
chemical_list: D008727:Methotrexate