title: The results of strictureplasty in pediatric patients with multifocal Crohn's disease.
abstract: This study is a retrospective review of eight pediatric patients with multifocal intestinal Crohn's disease who underwent strictureplasty with or without concomitant bowel resection between January 1978 and April 1992. The patients ranged in age from 9.9 years to 18.5 years. Indications for surgery were partial intestinal obstruction (n = 6), failure of medial therapy or steroid dependence (n = 4), growth failure (n = 2), and enterocutaneous fistula (n = 2). Thirty-six strictureplasties were performed in the eight patients (median, 4.5 strictureplasties per patient; range, 1-12). Bowel resection was performed in six of the eight patients in areas where strictureplasty was not feasible. The mean length of resection was 40 cm (range, 15-82 cm). The only complication was intestinal hemorrhage, which was conservatively managed in two patients. The patients were followed for a mean of 19 months (range, 3-55 months). Five patients had a weight below the fifth percentile prior to surgery. Postoperatively, there was a weight gain in seven patients, including all five patients who were originally below the fifth percentile. A statistically significant weight gain was found when a paired t test analysis was applied to the entire group (p = 0.04). Five of six patients who were on steroid medication at the time of surgery were successfully weaned within 1.5-3 months (mean, 2.3 months) from the time of surgery. Seven of eight patients had relief of their intestinal symptoms. Strictureplasty with small-bowel resection, or perhaps strictureplasty alone, in pediatric patients with multifocal intestinal Crohn's disease can improve gastrointestinal symptoms, promote weight gain, and allow discontinuation of steroid medications.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Cleveland Clinic Foundation, Ohio 44195.
authors.forename: L
authors.initials: L
authors.lastname: Oliva
authors.forename: R
authors.initials: R
authors.lastname: Wyllie
authors.forename: F
authors.initials: F
authors.lastname: Alexander
authors.forename: M
authors.initials: M
authors.lastname: Caulfield
authors.forename: R
authors.initials: R
authors.lastname: Steffen
authors.forename: I
authors.initials: I
authors.lastname: Lavery
authors.forename: V
authors.initials: V
authors.lastname: Fazio
mesh_terms: D000293:Adolescent; D002648:Child; D003424:Crohn Disease / Q000150:complications*; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery*; D008297:Male; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative / Q000379:methods