title: [Mechanisms of the stimulating effect of d-glucuronic acid on the processes of bone marrow granulomonocytopoiesis in cytostatic myelodepression].
abstract: The mechanisms of regulating influence of D-glucuronic acid on granulomonocytopoiesis++ have been studied by using the model of cyclophosphamide-induced myelodepression. Increase of colony-stimulating and interleukin-1 activities production by hemopoiesis inducing microenvironment cells, the stimulation of hemopoietic islets and the different granulomonocytopoiesis precursor cells forming have been shown to be the base of activating action of D-glucuronic acid on bone marrow granulomonocytopoiesis recovery.
authors.forename: E D
authors.initials: ED
authors.lastname: Gol'dberg
authors.forename: A M
authors.initials: AM
authors.lastname: Dygaĭ
authors.forename: G V
authors.initials: GV
authors.lastname: Karpova
authors.forename: E V
authors.initials: EV
authors.lastname: Simanina
authors.forename: I A
authors.initials: IA
authors.lastname: Khlusov
authors.forename: V P
authors.initials: VP
authors.lastname: Shakhov
authors.forename: V I
authors.initials: VI
authors.lastname: Agafonov
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D001854:Bone Marrow Cells; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D003520:Cyclophosphamide; D004195:Disease Models, Animal; D005965:Glucuronates / Q000494:pharmacology*; D020723:Glucuronic Acid; D006098:Granulocytes / Q000187:drug effects*; D006410:Hematopoiesis / Q000187:drug effects*; D006412:Hematopoietic Stem Cells / Q000187:drug effects; D007375:Interleukin-1 / Q000096:biosynthesis; D051379:Mice; D008808:Mice, Inbred CBA; D009000:Monocytes / Q000187:drug effects*; D013237:Stereoisomerism
chemical_list: D005965:Glucuronates; D007375:Interleukin-1; D020723:Glucuronic Acid; D003520:Cyclophosphamide
vernacular_title: O mekhanismakh stimuliruiushchego vliianie d-gliukuronovoĭ kisloty na protsessy kostnomozgovogo granulomonotsitopoéza v usloviiakh tsitostaticheskoĭ mielodepressii.