Prenatal exclusion of Duchenne muscular dystrophy by fetal muscle biopsy.
A fetal thigh muscle biopsy was performed at 18 weeks and 6 days' gestation using an automatic 18-gauge biopsy needle. A positive immunoreaction with antisera to the amino- and carboxy-terminals of dystrophin excluded Duchenne muscular dystrophy from this at-risk male.
Benzie
R J
RJ
Department of Obstetrics and Gynaecology, University of Ottawa, Canada.
Ray
P
P
Thompson
D
D
Hunter
A G
AG
Ivey
B
B
Salvador
L
L
D000328:Adult; D001707:Biopsy, Needle / Q000009:adverse effects / Q000379:methods; D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D005865:Gestational Age; D006801:Humans; D007223:Infant; D008297:Male; D009132:Muscles / Q000473:pathology*; D009136:Muscular Dystrophies / Q000473:pathology*; D010375:Pedigree; D011247:Pregnancy; D011296:Prenatal Diagnosis