title: Childbearing in women with and without a history of affective disorder. I. Psychiatric symptomatology.
abstract: Psychiatric symptoms and morbidity were examined prospectively in 34 obstetrically healthy volunteers recruited early in pregnancy. All women were free of current psychiatric disorder. Fourteen women had a history of affective disorder, and 20 had no lifetime history of any psychiatric disorder. Symptoms were assessed using both clinician- and self-administered ratings at specified points from 12 weeks of gestation through 8 months' postpartum. All women reported mild symptom elevation during pregnancy and the early puerperium, regardless of psychiatric history. The most frequently endorsed symptoms in both groups were somatic. However, women with a history of affective disorder reported more psychic and somatic distress than women with no psychiatric history. Onset of a psychiatric disorder did not occur during pregnancy in this sample, and only one woman, with both a personal and family history of affective disorder, met criteria for a new episode postpartum. Brief periods of symptom elevation occurred postpartum for 14.7% of the sample (five women, two with and three without a personal history of affective disorder) in the context of additional life stressors combining with the stress of new motherhood. These findings suggest that the impact of childbearing alone on psychiatric symptoms and morbidity is modest among women who are psychiatrically healthy at pregnancy onset and have sound social support networks.
authors.affiliation: Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15213-2593.
authors.forename: P A
authors.initials: PA
authors.lastname: Coble
authors.forename: C F
authors.initials: CF
authors.lastname: Reynolds
authors.forename: D J
authors.initials: DJ
authors.lastname: Kupfer
authors.forename: P R
authors.initials: PR
authors.lastname: Houck
authors.forename: N L
authors.initials: NL
authors.lastname: Day
authors.forename: D E
authors.initials: DE
authors.lastname: Giles
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000175:diagnosis* / Q000235:genetics / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D010552:Personality Assessment; D010555:Personality Inventory; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000523:psychology*; D011644:Puerperal Disorders / Q000175:diagnosis / Q000235:genetics / Q000523:psychology*; D012307:Risk Factors