title: Myocardial revascularization in patients with severe ischaemic left ventricular dysfunction: a clinical experience.
abstract: The benefits of myocardial revascularization in patients with ischaemic left ventricular dysfunction are widely reported. However, myocardial revascularization in such cases is associated with higher mortality and morbidity rates. Sixty patients with severe left ventricular dysfunction underwent myocardial revascularization at the authors' institution. Ejection fraction was assessed by angiocardioscintigraphy before and at 3 months after surgery. All patients underwent elective surgery and received complete myocardial revascularization. Myocardial protection was achieved using Buckberg's protocol. One perioperative death occurred. Weaning from cardiopulmonary bypass required inotropic drug therapy in 22 cases and aortic counterpulsation in nine. Perioperative myocardial infarction occurred in three patients with no further haemodynamic impairment. The mean postoperative ejection fraction was 41.0%, compared with a mean preoperative value of 26.5%. The extent of left ventricular functional improvement was greatest in those patients having the worst preoperative left ventricular function. It is concluded that, with this technique, myocardial revascularization can be achieved in patients with severe left ventricular dysfunction with an acceptable operative mortality.
authors.affiliation: Institute for Cardiovascular and Respiratory Diseases, University of Milan, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Paolini
authors.forename: M
authors.initials: M
authors.lastname: Zuccari
authors.forename: M A
authors.initials: MA
authors.lastname: Mariani
authors.forename: G
authors.initials: G
authors.lastname: Di Credico
authors.forename: M
authors.initials: M
authors.lastname: Pocar
authors.forename: L
authors.initials: L
authors.lastname: Galli
authors.forename: A
authors.initials: A
authors.lastname: Grossi
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000601:surgery*; D009204:Myocardial Revascularization; D013318:Stroke Volume; D016277:Ventricular Function, Left