[Effect of N-palmitoyl- and N-stearoylethanolamines on lipid peroxidation in mouse tissues in metastatic Lewis carcinoma].
The ability of two-cell minor lipid components: N-palmitoyl- and N-stearoylethanolamines to influence the Lewis lung carcinoma metastases has been studied. It is shown that these compounds decrease the quantity and the volume of metastases. Acyl derivatives of ethanolamine inhibit simultaneously the process of lipid peroxidation. Mice C57 B1/6 were intraperitonealy injected labeled 3H-N-stearoylethanolamine. Localization of this radioactive label in some organs of the animals was studied.
Gulaia
N M
NM
Smirnov
I M
IM
Shmal'ko
Iu P
IuP
Mel'nik
A A
AA
Mel'nik
S N
SN
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D004983:Ethanolamines / Q000494:pharmacology; D006321:Heart / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects*; D008099:Liver / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D009362:Neoplasm Metastasis; D010169:Palmitic Acids / Q000494:pharmacology; D013229:Stearic Acids / Q000494:pharmacology
D000970:Antineoplastic Agents; D004983:Ethanolamines; C022203:N-acylethanolamines; D010169:Palmitic Acids; D013229:Stearic Acids
Vliianie N-pal'mitoil- i N-stearoilétanolaminov na perekisnoe okislenie lipidov v tkaniiakh myseĭ pri metastazirovanii kartsinomy L'iuis.