title: Artificial bone erosions: detection with magnification radiography versus conventional high-resolution radiography.
abstract: OBJECTIVE
  To compare the diagnostic performance of direct magnification radiography with computed radiography versus that of conventional radiography in detection of artificial bone erosions.
  
  
  METHODS
  Thirty-one paws from German shepherd dogs were embedded in paraffin and examined with x6 magnification radiography and conventional radiography before and after creation of artificial bone erosions. A microfocal x-ray unit with a focal spot of 20-130 microns was used for magnification radiography. All 210 images were analyzed by five radiologists, and receiver operating characteristic (ROC) analysis was performed. Interobserver analysis in evaluation of anatomic structures was also performed.
  
  
  RESULTS
  ROC analysis of pooled data from all readers showed a larger area under the ROC curve for magnification radiography (0.88) than for conventional radiography (0.72). Magnification radiography produced higher scores in interobserver analysis as well.
  
  
  CONCLUSIONS
  Magnification radiography is superior to conventional radiography in detection of small bone erosions.
authors.affiliation: Department of Clinical Radiology, Westfälische Wilhelms-Universität, Münster, Germany.
authors.forename: T M
authors.initials: TM
authors.lastname: Link
authors.forename: E J
authors.initials: EJ
authors.lastname: Rummeny
authors.forename: H
authors.initials: H
authors.lastname: Lenzen
authors.forename: I
authors.initials: I
authors.lastname: Reuter
authors.forename: N
authors.initials: N
authors.lastname: Roos
authors.forename: P E
authors.initials: PE
authors.lastname: Peters
mesh_terms: D000818:Animals; D001168:Arthritis / Q000000981:diagnostic imaging; D001847:Bone Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D005121:Extremities; D005384:Finger Joint / Q000000981:diagnostic imaging; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging; D015588:Observer Variation; D012372:ROC Curve; D011858:Radiographic Magnification; D011877:Radionuclide Imaging