title: 5-[(3-nitropyrid-2-yl)amino]indoles: novel serotonin agonists with selectivity for the 5-HT1D receptor. Variation of the C3 substituent on the indole template leads to increased 5-HT1D receptor selectivity.
authors.affiliation: Department of Medicinal Chemistry, Central Research Division, Pfizer Inc, Groton, Connecticut 06340.
authors.forename: J E
authors.initials: JE
authors.lastname: Macor
authors.forename: D H
authors.initials: DH
authors.lastname: Blank
authors.forename: C B
authors.initials: CB
authors.lastname: Fox
authors.forename: L A
authors.initials: LA
authors.lastname: Lebel
authors.forename: M E
authors.initials: ME
authors.lastname: Newman
authors.forename: R J
authors.initials: RJ
authors.lastname: Post
authors.forename: K
authors.initials: K
authors.lastname: Ryan
authors.forename: A W
authors.initials: AW
authors.lastname: Schmidt
authors.forename: D W
authors.initials: DW
authors.lastname: Schulz
authors.forename: B K
authors.initials: BK
authors.lastname: Koe
mesh_terms: D007211:Indoles / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D008968:Molecular Conformation; D015394:Molecular Structure; D011985:Receptors, Serotonin / Q000187:drug effects*; D017366:Serotonin Receptor Agonists / Q000138:chemical synthesis* / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D018170:Sumatriptan / Q000378:metabolism / Q000494:pharmacology
chemical_list: D007211:Indoles; D011985:Receptors, Serotonin; D017366:Serotonin Receptor Agonists; C088802:CP 124439; D018170:Sumatriptan