title: [Bronchial asthma in a hyperendemic focus of opisthorchiasis (western Siberia)].
abstract: The data obtained on bronchial asthma (BA) occurrence in the hyperendemic opisthorchiasis focus in the western Siberia show BA in it to run a more severe and prognostically unfavourable course against the population from other Siberian regions safer by opisthorchiasis. The latter adapted to hepatobiliary system negatively affects the bronchi and lungs due to the involvement of eosinophilic and immunocomplex mechanisms damaging BA patients' shock organ. By means of additional antigenic stimulus, opisthorchiasis sensitization changes BA clinical manifestations and immunological manifestations status of BA patients dictating the necessity of immunological correction. High BA incidence was registered among subjects who had come from areas where opisthorchiasis was encountered less frequently.
authors.forename: V T
authors.initials: VT
authors.lastname: Volkov
authors.forename: F F
authors.initials: FF
authors.lastname: Tetenev
authors.forename: T N
authors.initials: TN
authors.lastname: Bodrova
mesh_terms: D000328:Adult; D001249:Asthma / Q000453:epidemiology*; D004197:Disease Reservoirs / Q000706:statistics & numerical data*; D004198:Disease Susceptibility; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009889:Opisthorchiasis / Q000453:epidemiology*; D012621:Seasons; D017678:Sex Distribution; D012800:Siberia / Q000453:epidemiology
vernacular_title: Bronkhial'naia astma v giperéndemicheskom ochage opistorkhoza (Zapadnaia Sibir').