Integrated human genome-wide maps constructed using the CEPH reference panel.
High resolution linkage maps have proven to be invaluable tools in genetic investigations. We have assembled a collection of genetic maps constructed from primary data collected from investigators performing genotyping using the Centre Etude Polymorphism Humain (CEPH) reference pedigree panel. These maps were constructed using a rigorous, semi-automated map construction algorithm that evaluates the integrity of the maps during construction. Two classes of maps were produced: a high confidence "skeletal" set composed of 544 PCR based markers, and a more highly annotated "framework" set containing maps of 1,123 markers. Genetic map locations within the framework maps are provided for an additional 1,758 loci without statistically unique interval assignments.
Buetow
K H
KH
Division of Population Science, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111.
Weber
J L
JL
Ludwigsen
S
S
Scherpbier-Heddema
T
T
Duyk
G M
GM
Sheffield
V C
VC
Wang
Z
Z
Murray
J C
JC
D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D002877:Chromosomes, Human; D016208:Databases, Factual; D005260:Female; D005602:France; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D007255:Information Services; D008297:Male; D010375:Pedigree; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
D005819:Genetic Markers