title: Detecting a major gene in an F2 population.
abstract: The aim of this paper is to study the behavior of the likelihood ratio test for the detection of a major gene in an F2 population. The model is a mixture of three normal distributions where the proportions are known. The information matrix is not positive definite, and therefore classical results cannot be used. An example concerning beans is given.
authors.affiliation: Institut National de la Recherche Agronomique, Station de Biométrie et d'Intelligence Artificielle, Chemin de Borde Rouge, Castanet-Tolosan, France.
authors.forename: P
authors.initials: P
authors.lastname: Loisel
authors.forename: B
authors.initials: B
authors.lastname: Goffinet
authors.forename: H
authors.initials: H
authors.lastname: Monod
authors.forename: G
authors.initials: G
authors.lastname: Montes De Oca
mesh_terms: D000818:Animals; D001699:Biometry; D003433:Crosses, Genetic; D008957:Models, Genetic; D015233:Models, Statistical; D010944:Plants / Q000235:genetics