Budd-Chiari syndrome: early intervention with angioplasty and thrombolytic therapy.
We present a complex case of the Budd-Chiari syndrome due to thrombosis of the hepatic veins in the presence of stenosis of the left hepatic vein and membranous obstruction of the inferior vena cava. The acute thrombosis occurred after laparoscopic surgical removal of the gallbladder. Because we strongly suspected the Budd-Chiari syndrome, hepatic venography was performed. The hepatic venous outflow obstruction was relieved by angioplasty and thrombolytic therapy with use of local infusions of urokinase into the clot. We propose that angiography be performed in patients in whom the Budd-Chiari syndrome is suspected and that angioplasty and thrombolytic therapy be initiated early.
Frank
J W
JW
Division of Gastroenterology and Internal Medicine, Mayo Clinic Rochester, Minnesota 55905.
Kamath
P S
PS
Stanson
A W
AW
D000328:Adult; D000465:Algorithms; D017130:Angioplasty; D006502:Budd-Chiari Syndrome / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015912:Thrombolytic Therapy