title: Effects of a tristearate-containing lipid and canola oil on plasma and tissue lipids in rats.
abstract: Male Sprague-Dawley rats were fed semipurified diets containing 12% fat and 0.4% cholesterol for 4 wk. The fats were palm oil, a high-stearate fat and canola oil; each of the latter two fat sources was substituted for palm oil in 4% (w/w) increments (i.e, 4, 8 and 12%) thus yielding 3 stearate-containing, 3 canola-containing, and a 12% palm oil diet. Stearate-fed animals exhibited significantly decreased food efficiency ratios, plasma total cholesterol, and liver cholesterol whereas the substitution of canola for palm oil did not consistently alter these parameters. Liver fatty acids generally reflected the composition of the dietary fat sources with the exception of significantly higher arachidonate observed in the stearate-fed rats.
authors.affiliation: Department of Home Economics (Nutrition) and Animal Science, University of Wyoming, Laramie 82071.
authors.forename: P
authors.initials: P
authors.lastname: Mani
authors.forename: M
authors.initials: M
authors.lastname: Liebman
authors.forename: D C
authors.initials: DC
authors.lastname: Rule
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000032:analysis / Q000097:blood; D004041:Dietary Fats / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D004435:Eating / Q000187:drug effects; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage / Q000494:pharmacology*; D008055:Lipids / Q000032:analysis* / Q000097:blood; D008099:Liver / Q000378:metabolism*; D008297:Male; D000073878:Palm Oil; D010938:Plant Oils / Q000008:administration & dosage / Q000494:pharmacology; D000074262:Rapeseed Oil; D051381:Rats; D017207:Rats, Sprague-Dawley; D013228:Stearates / Q000008:administration & dosage / Q000494:pharmacology*; D014280:Triglycerides / Q000097:blood
chemical_list: D004041:Dietary Fats; D005229:Fatty Acids, Monounsaturated; D008055:Lipids; D010938:Plant Oils; D000074262:Rapeseed Oil; D013228:Stearates; D014280:Triglycerides; D000073878:Palm Oil; D002784:Cholesterol