title: Application of an air-filled tube for measuring intraesophageal pressure.
abstract: We devised a new method for measuring esophageal pressure (Pes) with use of a flexible tube without a balloon at a constant rate of airflow through the tube into the esophagus (balloonless method). A study with 133Xe showed that the air that accumulated in the esophagus did not interfere with the measurement of Pes. We measured dynamic compliance (Cdyn) and pulmonary resistance (RL) with the balloonless method in 19 subjects and obtained a static deflation pressure-volume curve (P-V curve) in 10 other subjects. Cdyn was 0.243 +/- 0.099 l/cmH2O and RL was 1.52 +/- 0.42 cmH2O.l-1.s. In 6 of the 10 subjects, a P-V curve was also obtained with the balloon tube (balloon method). K, the index of compliance in the exponential function V = V0(1-e-KP) where V0 is volume at infinite pressure, was 0.136 +/- 0.040 cmH2O-1 with the balloonless method and 0.153 +/- 0.023 cmH2O-1 with the balloon method. No statistically significant difference was found between these two values. In conclusion, Cdyn, RL, and the P-V curve can be obtained precisely with the balloonless method.
authors.affiliation: Department of Medicine, Tohoku University, Sendai, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shiraishi
authors.forename: M
authors.initials: M
authors.lastname: Yaekashiwa
authors.forename: J
authors.initials: J
authors.lastname: Nakagawa
authors.forename: T
authors.initials: T
authors.lastname: Isawa
authors.forename: M
authors.initials: M
authors.lastname: Motomiya
mesh_terms: D000328:Adult; D000403:Airway Resistance / Q000502:physiology; D003187:Compliance; D004947:Esophagus / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D012129:Respiratory Function Tests; D014109:Total Lung Capacity; D014160:Transducers, Pressure; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes