title: Two different primary ophthalmic cancers in a 39-year-old female patient.
abstract: The clinical and histopathological findings are described in a 39-year-old female patient with two different primary ophthalmic cancers, involving the adnexa and ocular globe of the same eye. The first primary tumor was a malignant fibrous histiocytoma of the left lower eyelid aggressively invading the nasogenian region, bulbar conjunctiva, episclera, and the cornea over a 36-year follow-up period. The second primary cancer was an unsuspected choroidal malignant melanoma unexpectedly found at histology. The possible correlations between these two malignancies are discussed.
authors.affiliation: Department of Ophthalmology, Medical School, University of Cluj-Napoca.
authors.forename: M
authors.initials: M
authors.lastname: Călugăru
authors.forename: M
authors.initials: M
authors.lastname: Barsu
authors.forename: A
authors.initials: A
authors.lastname: Rotaru
authors.forename: C
authors.initials: C
authors.lastname: Ciuce
mesh_terms: D000328:Adult; D002830:Choroid Neoplasms / Q000473:pathology* / Q000601:surgery; D002908:Chronic Disease; D005123:Eye / Q000473:pathology; D015353:Eye Enucleation; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D013997:Time Factors