Mechanisms of the human allergic response. Clinical implications.
During the past decade, there have been enormous strides made in our understanding of the mechanisms underlying the human allergic response. In particular, interleukin-4 and interleukin-5 play a critical role in this process. This article details the understanding of the mechanisms underlying the regulation of allergic response, which is critical to the development of new treatment of allergic diseases.
Leung
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Division of Pediatric Allergy-Immunology, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado.
D000208:Acute Disease; D002908:Chronic Disease; D016207:Cytokines / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D007111:Immunity, Cellular / Q000276:immunology; D007073:Immunoglobulin E / Q000096:biosynthesis / Q000737:chemistry / Q000276:immunology*; D007249:Inflammation / Q000276:immunology; D007371:Interferon-gamma / Q000276:immunology; D015847:Interleukin-4 / Q000276:immunology; D017455:Receptors, IgE / Q000145:classification / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D016207:Cytokines; D017455:Receptors, IgE; D015847:Interleukin-4; D007073:Immunoglobulin E; D007371:Interferon-gamma