title: Technegas: a study of particle structure, size and distribution.
abstract: Technegas (TcG) was produced using a commercially available TcG generator. The structure and size distribution of TcG particles were examined by means of the following methods: (a) transmission electron microscopy (TEM), range: 1 nm-100 microns; (b) time-of-flight mass spectroscopy (MS), range: < 3 nm; (c) photon correlation spectroscopy (PCS), range: 3 nm-3 microns. The TEM images showed graphite particles (size 7-23 nm) agglomerated into larger secondary aggregates. The size of these aggregates, determined from PCS and TEM measurements, showed a log-normal distribution and typically ranged from 60 to 160 nm. No isolated particles smaller than 3 nm could be detected by MS. We conclude that TcG particles consist of technetium-99m labelled agglomerated graphite particles and have an average size of 97 nm (geometrice standard deviation (GSD): 1.55).
authors.affiliation: Rntgeninstitut Dres. Oei/Lemb/Wenz, Bremerhaven, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Lemb
authors.forename: T H
authors.initials: TH
authors.lastname: Oei
authors.forename: H
authors.initials: H
authors.lastname: Eifert
authors.forename: B
authors.initials: B
authors.lastname: Günther
mesh_terms: D010316:Particle Size; D010865:Pilot Projects; D011876:Radionuclide Generators; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D014691:Ventilation
chemical_list: C056708:Technegas; D013670:Sodium Pertechnetate Tc 99m