title: Adenoma malignum of the uterine cervix detected by imaging methods in a patient with Peutz-Jeghers syndrome.
abstract: Adenoma malignum of the uterine cervix in a 25-year-old Japanese woman with Peutz-Jeghers syndrome (PJS) is described. A cervical multicystic mass was detected by CT scan, sonography, and MR imaging. These imaging findings strongly suggested the presence of adenoma malignum in spite of normal Pap smear, colposcopy, and cervical biopsy reports. Radical hysterectomy, bilateral salpingo-oophorectomy, pelvic lymphadenectomy, and para-aortic lymph node biopsy were performed after confirmation of adenoma malignum by conization. Both ovaries showed multicentric sex cord tumor with annular tubules. She is alive and well with no evidence of disease 23 months after surgery. Imaging methods including sonography, CT scan, and MR imaging may be useful aids in detecting the presence of adenoma malignum, especially in patients with PJS.
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Tsuruchi
authors.forename: N
authors.initials: N
authors.lastname: Tsukamoto
authors.forename: T
authors.initials: T
authors.lastname: Kaku
authors.forename: T
authors.initials: T
authors.lastname: Kamura
authors.forename: H
authors.initials: H
authors.lastname: Nakano
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging; D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010580:Peutz-Jeghers Syndrome / Q000150:complications*; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging