title: Olfactory neuroblastoma invading the oral cavity in a patient with inappropriate antidiuretic hormone secretion.
abstract: Olfactory neuroblastoma is an uncommon intranasal neoplasm that has not been previously documented to invade the oral cavity. The tumor's variable clinical manifestations and microscopic features may create a diagnostic dilemma for the clinician. The neoplasm has been identified as a direct cause of ectopic arginine vasopressin production leading to inappropriate antidiuretic hormone secretion. An unusual case of olfactory neuroblastoma invading the oral cavity through the maxillary sinus in a patient with pathologic antidiuretic hormone secretion is reported.
authors.affiliation: Department of Diagnostic and Surgical Sciences, College of Dentistry, University of Saskatchewan, Saskatoon, Canada.
authors.forename: S L
authors.initials: SL
authors.lastname: Myers
authors.forename: D A
authors.initials: DA
authors.lastname: Hardy
authors.forename: C B
authors.initials: CB
authors.lastname: Wiebe
authors.forename: J
authors.initials: J
authors.lastname: Shiffman
mesh_terms: D000368:Aged; D001127:Arginine Vasopressin / Q000096:biosynthesis; D018304:Esthesioneuroblastoma, Olfactory / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology*; D008444:Maxillary Sinus Neoplasms / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009669:Nose Neoplasms / Q000150:complications* / Q000473:pathology
chemical_list: D001127:Arginine Vasopressin