Kimura's disease with high serum levels of eosinophil cationic protein and major basic protein.
This study reports a case of Kimura's disease. The patient was a 58-year-old man and satisfied the clinico-pathological findings of Kimura's disease. Serum eosinophil cationic protein (ECP) and major basic protein (MBP) levels in this patient were also measured. In the active stage of the disease, the patient's serum ECP and MBP levels were higher than those of healthy controls and declined in the remission stage. This finding suggests that ECP and MBP may be important agents in the development of Kimura's disease.
Morita
H
H
Department of Dermatology, Hyogo College of Medicine, Japan.
Kitano
Y
Y
D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000097:blood* / Q000188:drug therapy; D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D047091:Eosinophil Granule Proteins; D006801:Humans; D008297:Male; D051379:Mice; D008875:Middle Aged; D012260:Ribonucleases; D014221:Triamcinolone / Q000627:therapeutic use
D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D014221:Triamcinolone; D012260:Ribonucleases