Rest tremor and extrapyramidal symptoms after midbrain haemorrhage: clinical and 18F-dopa PET evaluation.
A 25 year old man had an acute subarachnoid haemorrhage due to the rupture of a right peduncular subthalamic arteriovenous malformation. Seven months later he developed a left rest tremor associated with mild bilateral extrapyramidal symptoms and responsive to levodopa treatment. Surface EMG recording showed synchronous activity of agonist and antagonist muscles in the left limbs. A PET 18F-dopa study showed a large decrease of the Ki value in the right striatum. One year after the stroke a persistent postural component developed in the tremor.
Defer
G L
GL
Départment de Neurosciences, Hôpital Henri Mondor, Créteil, France.
Remy
P
P
Malapert
D
D
Ricolfi
F
F
Samson
Y
Y
Degos
J D
JD
D000328:Adult; D001480:Basal Ganglia Diseases / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D004576:Electromyography; D005462:Fluorine Radioisotopes; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications*; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008636:Mesencephalon; D011187:Posture / Q000502:physiology; D012146:Rest; D012422:Rupture, Spontaneous; D013345:Subarachnoid Hemorrhage / Q000150:complications* / Q000000981:diagnostic imaging*; D013788:Thalamus; D014055:Tomography, Emission-Computed; D014202:Tremor / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology
D005462:Fluorine Radioisotopes; C043437:fluorodopa F 18; D007980:Levodopa; D004295:Dihydroxyphenylalanine