[Cardioprotective effects of adaptogens of plant origin].
The experiments performed on emotional--painful stress model in rats demonstrated cardioprotective activity of adaptogens of vegetable origin (rodiolae, eleutherococcus, levsea, p-tyrosol). Preliminary injection of rodiolae extract was found to prevent stress--induced increase in cAMP level and cGMP content decrease in heart. We can conclude that adaptogens cardioprotective effect may be the drugs to prevent stressor change in cyclic nucleotides level in myocardium.
Maslova
L V
LV
Lishmanov
Iu B
IuB
Maslov
L N
LN
D000222:Adaptation, Physiological; D000818:Animals; D009202:Cardiomyopathies / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D008297:Male; D009712:Nucleotides, Cyclic / Q000378:metabolism; D010936:Plant Extracts / Q000627:therapeutic use*; D051381:Rats; D013312:Stress, Physiological / Q000150:complications / Q000188:drug therapy*
D009712:Nucleotides, Cyclic; D010936:Plant Extracts
Kardioprotektornye éffekty adaptogenov rastitel'nogo proiskhozhdeniia.