title: Serum hepatitis in two brood mares.
abstract: Two adult Quarter Horse mares from the same farm developed signs of hepatic disease approximately 2 months after parturition. Both mares had received tetanus antitoxin at the time of foaling. One mare developed subcutaneous edema of the distal aspect of all 4 limbs, photodermatitis involving unpigmented areas of skin, and high serum activities of liver-specific enzymes. The other mare had signs of acute hepatic failure, including icterus, hepatic encephalopathy, and high serum activities of liver-specific enzymes, and died. The second mare had signs typical of serum hepatitis (Theiler's disease) and the first mare was believed to have had an atypical, less-severe form of serum hepatitis. Hepatotoxic agents (eg, poisonous plants, aflatoxins, toxic chemicals) were not found on the farm.
authors.affiliation: Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211.
authors.forename: N T
authors.initials: NT
authors.lastname: Messer
authors.forename: P J
authors.initials: PJ
authors.lastname: Johnson
mesh_terms: D000818:Animals; D005260:Female; D006520:Hepatitis, Animal / Q000209:etiology / Q000628:therapy; D006734:Horse Diseases / Q000209:etiology / Q000628:therapy; D006736:Horses; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D013743:Tetanus Antitoxin / Q000009:adverse effects
chemical_list: D013743:Tetanus Antitoxin