Genetic evidence for an additional member of the metalloproteinase-like, disintegrin-like, cysteine-rich (MDC) family of mammalian proteins and its abundant expression in the testis.
Full-length clones have been isolated from a Macaca fascicularis cDNA library corresponding to a 2.65 kb mRNA present at high steady state levels in the testis. Sequence analysis suggests that the predicted translation product, tMDC II protein, represents a novel member of the metalloproteinase-like, disintegrin-like, cysteine-rich (MDC) family of mammalian proteins.
Perry
A C
AC
Department of Biochemistry, University of Bristol, UK.
Barker
H L
HL
Jones
R
R
Hall
L
L
D051722:ADAM Proteins; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003545:Cysteine / Q000032:analysis*; D018076:DNA, Complementary / Q000737:chemistry / Q000302:isolation & purification; D019483:Disintegrins; D015723:Gene Library; D008252:Macaca fascicularis; D008297:Male; D008666:Metalloendopeptidases / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D010455:Peptides / Q000235:genetics; D011506:Proteins / Q000737:chemistry / Q000235:genetics*; D012333:RNA, Messenger / Q000737:chemistry; D016415:Sequence Alignment; D013737:Testis / Q000201:enzymology*
D018076:DNA, Complementary; D019483:Disintegrins; D010455:Peptides; D011506:Proteins; D012333:RNA, Messenger; D051722:ADAM Proteins; D008666:Metalloendopeptidases; D003545:Cysteine