Differential diagnosis of ovarian tumors by transvaginal color-pulse Doppler sonography.
To investigate the clinical significance of transvaginal color-pulse Doppler sonography in ovarian tumors, 109 patients were examined at Nagoya University Hospital. Ultrasonographic patterns were classified and the levels of three circulating tumor markers, CA125, CA72-4, and CA19-9, were simultaneously evaluated. In differentiating benign and malignant ovarian tumors, transvaginal color-pulse Doppler and ultrasonographic pattern classification were superior to the tumor markers. Of 49 cases with benign pattern, 45 were benign (91.8%). Of 60 cases with malignant pattern, 24 (40%) were benign and 36 (60%) were malignant or borderline malignant. In this group color-pulse Doppler sonography was the most useful procedure, and sensitivity, specificity, and accuracy were 75.0, 79.2, and 76.7%, respectively. Menopausal status and site of the arterial wave form in the tumor were also important. Transvaginal color-pulse Doppler sonography was a reliable diagnostic method for differentiating ovarian tumors.
Kawai
M
M
Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Japan.
Kikkawa
F
F
Ishikawa
H
H
Tamakoshi
K
K
Maeda
O
O
Hasegawa
N
N
Mizuno
K
K
Suzuki
A
A
Itakura
A
A
Nakashima
N
N
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000276:immunology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D014408:Biomarkers, Tumor / Q000276:immunology; D003536:Cystadenocarcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000276:immunology*; D012680:Sensitivity and Specificity; D014463:Ultrasonography
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor