New developments in tuberculosis and HIV infection: an opportunity for prevention.
As we approach 2010, the year by which we were to have eliminated TB, we find this ancient disease is making a comeback. This comeback is due to many factors, but the role of HIV infection is clearly important. HIV infection can result in changes in the pathogenesis and presentation of infection with the tubercle bacillus. Consequently, as health care providers, we must respond with changes in our usual methods of prevention, treatment, and infection control. Whereas the increase in TB is currently limited to certain geographic areas, it is likely to spread more widely. All health care providers should be aware of the changing face of TB and have a high clinical index of suspicion for this disease.
Curtis
J R
JR
Robert Wood Johnson Clinical Scholars Program, Department of Medicine, University of Washington, Seattle 98105.
Hooton
T M
TM
Nolan
C M
CM
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000517:prevention & control*; D000995:Antitubercular Agents / Q000627:therapeutic use; D003140:Communicable Disease Control; D004196:Disease Outbreaks / Q000517:prevention & control*; D006801:Humans; D017053:Infection Control; D018088:Tuberculosis, Multidrug-Resistant / Q000453:epidemiology / Q000517:prevention & control*; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000517:prevention & control*; D014481:United States / Q000453:epidemiology
D000995:Antitubercular Agents