title: Characterization of a cDNA encoding the precursor of platelet aggregation inhibition and metalloproteinase from Trimeresurus mucrosquamatus venom.
abstract: This paper presents the nucleotide sequence of a cDNA encoding a full-length precursor of a novel platelet aggregation inhibitor named trimucrin and a hemorrhagic metalloproteinase from Trimeresurus mucrosquamatus snake venom. The deduced structure of the precursor protein is compared with those of other members of the metalloproteinase/disintegrin family.
authors.affiliation: Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
authors.forename: I H
authors.initials: IH
authors.lastname: Tsai
authors.forename: Y M
authors.initials: YM
authors.lastname: Wang
authors.forename: Y H
authors.initials: YH
authors.lastname: Lee
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003435:Crotalid Venoms / Q000235:genetics*; D018076:DNA, Complementary; D004792:Enzyme Precursors / Q000235:genetics*; D008666:Metalloendopeptidases / Q000235:genetics*; D008969:Molecular Sequence Data; D010455:Peptides / Q000235:genetics*; D010975:Platelet Aggregation Inhibitors; D017386:Sequence Homology, Amino Acid; D017841:Trimeresurus / Q000235:genetics*
chemical_list: D003435:Crotalid Venoms; D018076:DNA, Complementary; D004792:Enzyme Precursors; D010455:Peptides; D010975:Platelet Aggregation Inhibitors; C029748:Trimeresurus venoms; C089139:trimucrin; D008666:Metalloendopeptidases