[The effect of membrane-stabilizing therapy on the status of the hemostatic system in patients with glomerulonephritis with a hematuric component].
Hyperfibrinogenaemia, hyperthrombinaemia, slowed down lysis of euglobulin clot, increased level of plasminogen, delayed aggregation of thrombocytes were observed in 20 patients with glomerulonephritis with haematuria. Membrane-stabilizing therapy reduced trends to hypercoagulation, significantly improved aggregating abilities of thrombocytes. Considerable impact of membrane-stabilizing therapy on indices of haemostasis in patients with hematuric glomerulonephritis evidences close link to exist between activation of lipid peroxidation, changes of structural and functional parameters of membranes and mechanisms of blood coagulation and thrombocyte aggregation.
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D001778:Blood Coagulation Disorders / Q000097:blood / Q000188:drug therapy / Q000209:etiology; D001780:Blood Coagulation Tests; D004359:Drug Therapy, Combination; D005342:Fibrinolysis; D005921:Glomerulonephritis / Q000097:blood* / Q000150:complications / Q000188:drug therapy*; D006417:Hematuria / Q000097:blood* / Q000150:complications / Q000188:drug therapy*; D006487:Hemostasis; D006801:Humans; D015227:Lipid Peroxidation; D013997:Time Factors
Vplyv membranostabilizuiuchoï terapiï na stan hemostazu u khvorykh na hlomerulonefryt z hematurychnym komponentom.