[Pneumocystis carinii pneumonia in HIV-infected patients examined by bronchoscopy during the period 1989-1991].
We analyzed prospectively collected data from 211 HIV-infected patients who underwent bronchoscopy because of pulmonary symptoms during the period 1989-1991. We found an improvement in survival for patients diagnosed with Pneumocystis carinii pneumonia (PCP) in 1991 as compared to 1989 and 1990 (log rank test: p = 0.07). A significant decline in PO2 and CD4 cell count was observed in patients with PCP in the same period (p < 0.05 and 0.005 respectively). We suggest that the decline in CD4 cell count and in PO2 may reflect a change in Pneumocystis carinii transmission, and that the improved survival may be a result of altered treatment strategy of PCP.
Jensen
A M
AM
Infektionsmedicinsk afdeling, Hvidovre Hospital, København.
Lundgren
J D
JD
Nielsen
T L
TL
Benfield
T L
TL
Vestbo
J
J
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000276:immunology / Q000401:mortality; D001999:Bronchoscopy; D015704:CD4 Antigens / Q000032:analysis; D005260:Female; D015658:HIV Infections / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008297:Male; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis* / Q000276:immunology / Q000401:mortality; D011379:Prognosis; D011446:Prospective Studies
D015704:CD4 Antigens
Pneumocystis carinii pneumoni hos HIV-smittede udredt med bronkoskopi i perioden 1989-1991.