Acute tumor lysis syndrome complicating conditioning therapy for bone marrow transplantation in a patient with chronic lymphocytic leukemia.
We report a case of acute tumor lysis syndrome appearing during chemoradiotherapeutic conditioning for allogeneic bone marrow transplantation (BMT) in a patient with chronic lymphocytic leukemia. This complication appeared in spite of prophylactic therapy and although the outcome was satisfactory, the patient required temporary hemodialysis and strict supportive care. This case emphasizes the importance of recognizing that the acute tumor lysis syndrome is not confined to high-grade malignancies.
Nomdedéu
J
J
Department d'Hematologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Martino
R
R
Sureda
A
A
Huidobro
G
G
López
R
R
Brunet
S
S
Domingo-Albós
A
A
D000208:Acute Disease; D000970:Antineoplastic Agents / Q000009:adverse effects*; D016026:Bone Marrow Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*; D014184:Transplantation, Homologous; D015275:Tumor Lysis Syndrome / Q000209:etiology*; D014916:Whole-Body Irradiation
D000970:Antineoplastic Agents