[The effect of thymalin on the development of sensitization with a soluble microbial antigen and on the phenotypic composition of lymphocyte subpopulations in the organs of immunity].
The influence of thymalin on the formation of specific allergy and the distribution of immunocompetent cells in the immunity organs of guinea pigs immunized with Haemophilus influenzae antigen was studied. The stimulating influence of thymalin on the allergization of the body, changes in the lymphocyte subpopulations, as well as the possibility of the development of allergic reactions to thymalin, were established. Multiple injections of thymalin produced a stronger stimulating effect on the formation of specific microbial allergy and on the content of T- and B-lymphocytes than a single injection of the preparation.
Sukhodoeva
G S
GS
Shamsutdinova
G S
GS
Dobritsa
V P
VP
Ospanova
E N
EN
Lukpanova
Sh Z
ShZ
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology; D005260:Female; D006168:Guinea Pigs; D006193:Haemophilus influenzae / Q000276:immunology*; D006968:Hypersensitivity, Delayed / Q000209:etiology / Q000276:immunology; D006969:Hypersensitivity, Immediate / Q000209:etiology / Q000276:immunology; D007107:Immune System / Q000187:drug effects* / Q000276:immunology; D007114:Immunization; D016130:Immunophenotyping; D016131:Lymphocyte Subsets / Q000187:drug effects* / Q000276:immunology; D008297:Male; D012995:Solubility; D013951:Thymus Hormones / Q000494:pharmacology*; D013997:Time Factors
D000276:Adjuvants, Immunologic; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D013951:Thymus Hormones; C032805:thymalin
Vliianie timalina na formirovanie sensibilizatsii rastvorimym mikrobnym antigenom i fenotipicheskiĭ sostav subpopuliatsiĭ limfotsitov v organakh immuniteta.