title: Attachment of epithelial cells and fibroblasts to ceramic materials.
abstract: This study examined in vitro gingival epithelial and fibroblast cell attachment to ceramic materials made of tricalcium phosphate and/or magnesium aluminate spinel. The composite made of tricalcium phosphate and spinel is called 'osteoceramic'. These ceramics had various compositions and surface structures, which were initially characterized. Cell attachment assays were performed using both cell types to compare cellular response to the ceramic materials. Specimens were also prepared for scanning electron microscopy to investigate cellular morphology. The highest levels of cell attachment for gingival epithelial cells were observed on the rough osteoceramic surface, whereas gingival fibroblasts attached least to the rough osteoceramic surface.
authors.affiliation: Department of Biomedical Engineering, Iowa State University, Ames 50011.
authors.forename: G G
authors.initials: GG
authors.lastname: Niederauer
authors.forename: T D
authors.initials: TD
authors.lastname: McGee
authors.forename: J C
authors.initials: JC
authors.lastname: Keller
authors.forename: R S
authors.initials: RS
authors.lastname: Zaharias
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry; D002448:Cell Adhesion; D002478:Cells, Cultured; D002516:Ceramics / Q000737:chemistry; D004847:Epithelial Cells; D004848:Epithelium / Q000648:ultrastructure; D005347:Fibroblasts / Q000166:cytology* / Q000648:ultrastructure; D005881:Gingiva / Q000166:cytology* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D051381:Rats; D013499:Surface Properties; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous