title: Depressive symptoms in cancer patients undergoing chemotherapy: a psychometric analysis.
abstract: Depressive psychopathology was measured in a prospective follow-up study of 36 cancer patients. The psychometric properties of the Hamilton rating scales for depression and anxiety and the Melancholia Scale were examined. The scales proved useful, indicating that the symptomatic structure of depression in cancer patients is rather identical to that seen in primary depression. Depressive states were found in about 40% of patients before the start of chemotherapy. The frequency of intermediate and high scores on the depression scales showed a low to moderate decrease after 6 months. Aspects of depression in the medically ill are discussed, and screening routines suggested.
authors.affiliation: Department of Psychiatry, Bispebjerg University Hospital, Copenhagen, Denmark.
authors.forename: T
authors.initials: T
authors.lastname: Middelboe
authors.forename: L
authors.initials: L
authors.lastname: Ovesen
authors.forename: E L
authors.initials: EL
authors.lastname: Mortensen
authors.forename: P
authors.initials: P
authors.lastname: Bech
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000523:psychology; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000523:psychology; D003863:Depression / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy / Q000523:psychology*; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000523:psychology; D010555:Personality Inventory / Q000706:statistics & numerical data; D011446:Prospective Studies; D011594:Psychometrics; D012803:Sick Role
chemical_list: D000970:Antineoplastic Agents