Neurosonographic findings in full-term infants born to maternal cocaine abusers: visualization of subependymal and periventricular cysts.
Neuroanatomical abnormalities have been linked to maternal cocaine abuse since Chasnoff et al's report of cerebral infarction in a single full-term offspring of a cocaine-abusing mother. Neurosonography was performed on 18 full-term offspring of cocaine-abusing mothers and 19 age-matched controls to look for possible abnormalities. There were no cases of infarction or intraparenchymal or intraventricular hemorrhage. There were, however, 6 patients with abnormalities among the cocaine-abusing group: 5 patients with unilateral or bilateral germinal matrix cysts and 3 patients with subtle cystic or predominantly cystic areas in watershed zones consistent with periventricular leukomalacia.
Cohen
H L
HL
Department of Radiology, SUNY-Health Science Center at Brooklyn.
Sloves
J H
JH
Laungani
S
S
Glass
L
L
DeMarinis
P
P
D000328:Adult; D001921:Brain / Q000002:abnormalities; D001927:Brain Diseases / Q000000981:diagnostic imaging; D002421:Caudate Nucleus / Q000000981:diagnostic imaging; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging; D002544:Cerebral Infarction / Q000000981:diagnostic imaging; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging*; D003042:Cocaine; D016578:Crack Cocaine; D003560:Cysts / Q000000981:diagnostic imaging*; D004453:Echoencephalography; D004805:Ependyma / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D019966:Substance-Related Disorders; D013788:Thalamus / Q000000981:diagnostic imaging
D016578:Crack Cocaine; D003042:Cocaine