title: [Immunodepressive effect of transcerebral lasers].
abstract: The aim of the present paper was to study the effect of infrared laser radiation on endocrine regulation of immunogenesis and on endogenic opioid system. For this purpose experiments on rabbits were carried out. The animals underwent transcerebral radiation with subsequent induction of the primary immune response (PIR) to thymus-dependent antigen (sheep red blood cells). The PIR suppression was revealed in all test animals. It was more graphically expressed in rabbits exposed to impulse radiation. Immunodepression was combined with the increase of glucocorticoid activity of adrenal cortex, while no significant changes in thyroid hormones were registered. The 0.08 Joles impulse radiation cause a palpable fall in opioid concentration in blood plasma, the fact, which can be possibly accounted for the rapid exhaustion of opioid synthesis after their stimulation due to laser radiation.
authors.forename: T V
authors.initials: TV
authors.lastname: Konchugova
authors.forename: V A
authors.initials: VA
authors.lastname: Vinogradov
authors.forename: A A
authors.initials: AA
authors.lastname: Minenkov
authors.forename: A S
authors.initials: AS
authors.lastname: Bobkova
authors.forename: S B
authors.initials: SB
authors.lastname: Pershin
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000528:radiation effects; D001921:Brain; D004723:Endorphins / Q000528:radiation effects*; D005938:Glucocorticoids / Q000378:metabolism; D007030:Hypothalamo-Hypophyseal System / Q000528:radiation effects*; D007165:Immunosuppression Therapy / Q000379:methods*; D007259:Infrared Rays; D007834:Lasers; D008297:Male; D010913:Pituitary-Adrenal System / Q000528:radiation effects*; D011817:Rabbits; D012756:Sheep
chemical_list: D004723:Endorphins; D005938:Glucocorticoids
vernacular_title: Immunodepressivnyĭ éffekt transtserebral'nykh lazernykh vozdeĭstviĭ.