title: Distribution and morphological features of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) activity in intrinsic neurons of the Oddi sphincter of the cat.
abstract: To clarify the role of nitric oxide (NO) in the sphincter of Oddi, we histochemically investigated the distribution of nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d), a marker for NO synthase, in the cat. NADPH-diaphorase activity was localized in two neuronal subtypes: large neurons with many dendrites and smaller with one process. Most of the nerve cell bodies (99%) in the wall of the sphincter of Oddi showed strong activity for this enzyme. The nerve fibers with NADPH-d activity were observed in all layers, chiefly in the muscle layers. These results suggest that NO may play a very important role in the neuronal regulation of sphincter of Oddi.
authors.affiliation: First Department of Anatomy, Semmelweis University Medical School, Budapest, Hungary.
authors.forename: E
authors.initials: E
authors.lastname: Fehér
authors.forename: C
authors.initials: C
authors.lastname: Montagnese
mesh_terms: D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology; D002415:Cats; D005260:Female; D006651:Histocytochemistry; D008297:Male; D009252:NADPH Dehydrogenase / Q000378:metabolism*; D009474:Neurons / Q000201:enzymology* / Q000648:ultrastructure; D009569:Nitric Oxide / Q000378:metabolism / Q000502:physiology; D009803:Sphincter of Oddi / Q000033:anatomy & histology / Q000201:enzymology* / Q000294:innervation
chemical_list: D009569:Nitric Oxide; D009252:NADPH Dehydrogenase