title: Comparison of coronary angiographic findings during the first six hours of non-Q-wave and Q-wave myocardial infarction.
abstract: The angiographic features of non-Q-wave acute myocardial infarction (AMI) soon after symptom onset have not been previously reported. Accordingly, this study reviewed the coronary angiographic findings of 86 patients with AMI studied within 6 hours of symptom onset: 58 had Q-wave and 28 had non-Q-wave AMI. Patients with Q-wave and non-Q-wave AMI were comparable in terms of clinical characteristics, frequency of 1-vessel disease, and infarct-related artery location. Thrombus was observed in 49 patients (84%) with Q-wave AMI versus 12 (43%) with non-Q-wave AMI (p = 0.0002). Whereas complete occlusion of the infarct-related artery was present in 53 patients (91%) with Q-wave AMI, total coronary occlusion was present in only 11 (39%) with non-Q-wave AMI (p = 0.0001). Collaterals to occluded infarct arteries were seen in 10 patients (19%) with Q-wave AMI versus 5 (45%) with non-Q-wave AMI (p = 0.06). Residual perfusion of the infarct artery by either anterograde or collateral flow was typical of patients with non-Q-wave AMI (22 of 28, 79%) but was uncommon in those with Q-wave AMI (15 of 58, 26%) (p = 0.0001). Thus, coronary angiography performed within 6 hours of symptom onset demonstrates important differences between Q-wave and non-Q-wave AMI. Non-Q-wave AMI is characterized by partial perfusion of the infarct-related artery by either anterograde or collateral flow, and a lower incidence of thrombus than Q-wave AMI.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Division of Cardiology, Jefferson Medical College, Philadelphia, Pennsylvania.
authors.forename: W D
authors.initials: WD
authors.lastname: Keen
authors.forename: M P
authors.initials: MP
authors.lastname: Savage
authors.forename: D L
authors.initials: DL
authors.lastname: Fischman
authors.forename: A
authors.initials: A
authors.lastname: Zalewski
authors.forename: P
authors.initials: P
authors.lastname: Walinsky
authors.forename: D
authors.initials: D
authors.lastname: Nardone
authors.forename: S
authors.initials: S
authors.lastname: Goldberg
mesh_terms: D016009:Chi-Square Distribution; D003097:Collateral Circulation; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D012307:Risk Factors; D013997:Time Factors