[The alpha-glycerolphosphate dehydrogenase and adenosinetriphosphatase activity of the peripheral blood lymphocytes in diabetics (a cytochemical determination)].
Decrease in activity of alpha-GPDG and ATP-ase observed in peripheral lymphocytes of patients with diabetes mellitus correlated well severity of the disease. The lowest indices of enzymatic activity were registered in patients with grave diabetes complicated by angiopathies, foot gangrene, and purulent inflammatory processes. Compensation of carbohydrates metabolism and improvement of clinical picture were accompanied by the trend to normalization of enzymes' activity. Dynamic study of alpha-GPDG and ATP-ase in patients with diabetes mellitus allows to evaluate degree of hypoxia, comprehend the nature of compensation mechanisms and assess effectiveness of the treatment.
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D000251:Adenosine Triphosphatases / Q000097:blood*; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000201:enzymology*; D003925:Diabetic Angiopathies / Q000201:enzymology; D017719:Diabetic Foot / Q000201:enzymology; D005993:Glycerolphosphate Dehydrogenase / Q000097:blood*; D006651:Histocytochemistry; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology*; D008875:Middle Aged; D013997:Time Factors
D005993:Glycerolphosphate Dehydrogenase; D000251:Adenosine Triphosphatases
Aktyvnist' al'fa-hlitserofosfatdehidrohenazy i adenozyntryfosfatazy limfotsytiv peryferychnoï krovi khvorykh na tsukrovyĭ diabet (tsytokhimichne vyznachennia).