[Effect of furosemide on renal magnesium and calcium excretion of different ages (II)].
Thirty normal students, including senior high, junior high and elementary school, were the subject for furosemide test. Ten cases, in each age group, were given oral furosemide 2 mg/kg for three consecutive days. The result showed there were increasing urinary magnesium and calcium excretion among the three different age groups after oral furosemide (P < 0.05). Successive increase of urinary magnesium and calcium excretion of senior high school students is more obvious than those of junior high and elementary school students. It is suggested that there is more effective action on renal magnesium and calcium excretion for senior high school students after oral furosemide than that for the junior high and elementary school students. It is obvious that increasing dosage of furosemide would induce more calcium excretion than magnesium excretion among students of the three age groups. Therefore, it encouraged to drink the proper amount of water to decrease the incidence of hypercalciuric stone when furosemide should be used.
Lee
A J
AJ
Department of Pediatrics, Tri-Service General Hospital, National Defence Medical Center, Taipei, Taiwan, R.O.C.
Chen
Y H
YH
Chu
M L
ML
Chen
C H
CH
D000293:Adolescent; D000367:Age Factors; D002118:Calcium / Q000378:metabolism*; D002648:Child; D005665:Furosemide / Q000494:pharmacology*; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism*; D008297:Male
D005665:Furosemide; D008274:Magnesium; D002118:Calcium