title: Squamous cell carcinoma arising in recurrent odontogenic keratocyst: case report and literature review.
abstract: BACKGROUND
  Keratinizing odontogenic cysts of the mandible commonly have an aggressive clinical course, marked by multiple recurrences. Primary intraosseus carcinoma (PIOC) of the mandible is rare, and when it occurs it is often found to be arising in or closely associated with some type of cystic structure.
  
  
  METHODS
  A patient with squamous cell carcinoma arising from an odontogenic keratocyst is studied clinically, radiographically, and pathologically.
  
  
  RESULTS
  The patient who was documented to have an odontogenic keratocyst, 1 year later had a squamous carcinoma removed from the recurrent cyst.
  
  
  CONCLUSIONS
  We report the occurrence of squamous cell carcinoma arising from a recurrent odontogenic keratocyst, which has not previously been documented in the literature. The literature on this subject is reviewed.
authors.affiliation: Department of Pathology, Pennsylvania State University, College of Medicine, Hershey 17033.
authors.forename: D J
authors.initials: DJ
authors.lastname: Dabbs
authors.forename: R J
authors.initials: RJ
authors.lastname: Schweitzer
authors.forename: L E
authors.initials: LE
authors.lastname: Schweitzer
authors.forename: F
authors.initials: F
authors.lastname: Mantz
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D009807:Odontogenic Cysts / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011859:Radiography