Parental and medical over-administration of acetaminophen causing lethal hepatotoxicity in a 10-year-old.
A 10-year-old girl with acute influenza B virus disease was given repetitive doses of acetaminophen by her mother to reduce the child's fever. When finally seen by trained medical personnel, the child was experiencing abdominal pain, nausea, and vomiting, which are classic signs of acetaminophen hepatotoxicity. Despite these findings, the child was given additional acetaminophen and experienced lethal hepatotoxicity.
Nadir
A
A
Oklahoma Transplantation Institute, Baptist Medical Center of Oklahoma, Oklahoma City 73112.
McFadden
R
R
Griggs
J
J
Wright
H I
HI
Fagiuoli
S
S
Van Thiel
D H
DH
D000082:Acetaminophen / Q000506:poisoning*; D056486:Chemical and Drug Induced Liver Injury; D002648:Child; D062787:Drug Overdose; D017809:Fatal Outcome; D005260:Female; D006801:Humans
D000082:Acetaminophen