title: [Radiation-induced damage of mitochondrial genome and its role in long-term effects of irradiation].
abstract: The role of mt-genome mutations in radiation-induced carcinogenesis has been hypothesized. The data on radiation chemistry of nucleic acids has been used to evaluate mutagenic effect of carcinogenic doses of ionizing radiation. The assumptions about the ways of biological augmentation of primary radiation-induced lesions in mt-genome has been given.
authors.forename: N N
authors.initials: NN
authors.lastname: Berogovskaia
authors.forename: A V
authors.initials: AV
authors.lastname: Savich
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D000818:Animals; D002417:Cattle; D002471:Cell Transformation, Neoplastic; D004249:DNA Damage; D004270:DNA, Circular / Q000235:genetics / Q000378:metabolism / Q000528:radiation effects*; D004330:Drosophila; D006801:Humans; D015227:Lipid Peroxidation; D008099:Liver / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects; D051379:Mice; D008928:Mitochondria / Q000378:metabolism / Q000528:radiation effects*; D008930:Mitochondria, Liver / Q000378:metabolism / Q000528:radiation effects; D008954:Models, Biological; D009154:Mutation; D010085:Oxidative Phosphorylation; D011829:Radiation Dosage; D011839:Radiation, Ionizing
chemical_list: D004270:DNA, Circular; D000255:Adenosine Triphosphate
vernacular_title: Radiotsionnoe povrezhdenie genoma mitokhodriĭ i ego rol' v otdalennykh posledstviiakh oblucheniia.