title: Continuous positive airway pressure by mask in patients after coronary surgery.
abstract: Thirty patients who underwent coronary artery bypass grafting were randomized to receive 30% oxygen by mask either with an ambient airway pressure or with 7.4 mmHg (1 kPa) continuous positive airway pressure (CPAP) for 8 h after extubation. Arterial blood oxygen tension (PaO2) decreased remarkably in the control group after extubation (from 19.2 +/- 5.3 kPa to 12.4 +/- 2.7 kPa) but less in the CPAP group (from 16.4 +/- 3.3 kPa to 14.0 +/- 2.1 kPa). On the second postoperative morning PaO2 was equally low in both groups (control: 8.4 +/- 1.5 kPa, CPAP: 8.9 +/- 1.9 kPa). Atelectatic areas were seen with similar frequency in both groups, 17% (whole material) on the first and 50% on the second postoperative morning. Atelectasis was more common in patients with internal thoracic artery grafting and/or pleural drainage. In conclusion, CPAP therapy was well tolerated, and minimized the decrease in PaO2 after extubation, but could not prevent the poor oxygenation or the late development of atelectatic areas on the second postoperative day.
authors.affiliation: Department of Anaesthesia, Helsinki University Central Hospital, Finland.
authors.forename: I
authors.initials: I
authors.lastname: Jousela
authors.forename: J
authors.initials: J
authors.lastname: Räsänen
authors.forename: K
authors.initials: K
authors.lastname: Verkkala
authors.forename: A
authors.initials: A
authors.lastname: Lamminen
authors.forename: A
authors.initials: A
authors.lastname: Mäkeläinen
authors.forename: P
authors.initials: P
authors.lastname: Nikki
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D001026:Coronary Artery Bypass; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007902:Length of Stay; D008297:Male; D008397:Masks; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011175:Positive-Pressure Respiration / Q000379:methods*; D011182:Postoperative Care; D011651:Pulmonary Artery; D001261:Pulmonary Atelectasis / Q000209:etiology; D011669:Pulmonary Wedge Pressure / Q000502:physiology; D012119:Respiration / Q000502:physiology; D013530:Surgical Wound Infection / Q000209:etiology; D014655:Vascular Resistance / Q000502:physiology
chemical_list: D010100:Oxygen