Leuprolide acetate for exhibitionism in Huntington's disease.
We treated a patient with Huntington's disease and exhibitionism using leuprolide acetate (Lupron Depot, TAP Pharmaceuticals), a gonadotropin-releasing hormone agonist. The result was elimination of his deviant sexual behavior with few side effects. This regimen may be a safe and effective pharmacological treatment of the paraphilias. The occurrence of paraphilias in basal ganglia disorders is reviewed.
Rich
S S
SS
Department of Psychiatry, University of Chicago, Illinois.
Ovsiew
F
F
D000328:Adult; D003692:Delayed-Action Preparations; D003704:Dementia / Q000188:drug therapy* / Q000235:genetics / Q000523:psychology; D005084:Exhibitionism / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D006816:Huntington Disease / Q000188:drug therapy* / Q000235:genetics / Q000523:psychology; D007273:Injections, Intramuscular; D016729:Leuprolide / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D009460:Neurologic Examination / Q000187:drug effects
D003692:Delayed-Action Preparations; D016729:Leuprolide