Reversed-phase chromatography of small molecules and peptides on a continuous rod of macroporous poly(styrene-co-divinylbenzene).
A continuous "molded" rod of porous poly(styrene-co-divinylbenzene) prepared by a bulk free radical polymerization within the confines of a chromatographic column has been used successfully for the reversed-phase HPLC of alkylbenzenes and peptides. An excellent rapid separation of bradykinin and [D-Phe7]-bradykinin with a molecular mass of about 1000 was also achieved.
Wang
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QC
Cornell University, Department of Chemistry, Baker Laboratory, Ithaca, NY 14853-1301.
Svec
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Fréchet
J M
JM
D000595:Amino Acid Sequence; D001555:Benzene Derivatives / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D008969:Molecular Sequence Data; D010455:Peptides / Q000032:analysis*; D011137:Polystyrenes; D013056:Spectrophotometry, Ultraviolet
D001555:Benzene Derivatives; D010455:Peptides; D011137:Polystyrenes; C003771:Amberlite XAD-2 resin