title: Characteristics of transient otoacoustic emissions in patients with sudden idiopathic hearing loss.
abstract: In a prospective study of 24 patients hospitalized with sudden idiopathic hearing loss syndrome (SIHLS), tonal audiometry was conducted first at an early stage after onset (Day O), again a second time (Day A, mean = 4.12 days), and again a third time (Day B, mean = 8.71 days). Transient evoked otoacoustic emissions (TEOAE) were recorded on Days O and A elicited by click stimulation. The question under investigation was whether TEOAE presence, TEOAE amplitude or peak amplitudes for the various 200-Hz-wide bands on Day O could be exploited to assess cochlear function, as indicated by pure-tone audiometry on Days A and B. The TEOAE amplitude on Day O was found to be correlated with improvement in tone threshold on Day B at 2 kHz. One significant correlation emerged between the band amplitude on Day O and the audiometric frequency improvement: on Day B between peak amplitude at 1.2 kHz and 1 kHz frequency improvement. From these results, TEOAE could theoretically be a means to assess cochlear functioning during SIHLS for 1 and 2 kHz frequencies. However, correlations are too weak to form the basis of any predictive test that could be clinically useful.
authors.affiliation: Service d'Oto-Rhino-Laryngologie, de Chirurgie Cervico-faciale et de Phoniatrie, Hopital Edouard Herriot, Lyon, France.
authors.forename: E
authors.initials: E
authors.lastname: Truy
authors.forename: E
authors.initials: E
authors.lastname: Veuillet
authors.forename: L
authors.initials: L
authors.lastname: Collet
authors.forename: A
authors.initials: A
authors.lastname: Morgon
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000359:Aftercare; D000368:Aged; D001301:Audiometry, Pure-Tone / Q000379:methods; D003051:Cochlea / Q000503:physiopathology; D004359:Drug Therapy, Combination; D005260:Female; D006311:Hearing Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D010891:Piribedil / Q000627:therapeutic use; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D012044:Regression Analysis; D013577:Syndrome; D013997:Time Factors
chemical_list: D010891:Piribedil; D008775:Methylprednisolone