Mohs micrographic excision of sebaceous carcinoma of the eyelids.
BACKGROUND
Sebaceous carcinoma of the eyelid is a difficult tumor to manage because of diagnostic difficulties and pagetoid-type spread in the conjunctivae.


OBJECTIVE
We report our experience with eight patients using the Mohs technique of excision with reconstruction.


METHODS
Six cases were managed with paraffin-embedded hematoxylin and eosin sections. One case was managed by frozen histologic sections and one was managed with frozen section processing followed by paraffin-embedded section review.


RESULTS
The correct pathologic diagnosis was made initially in only 50% of the cases. Eighty-eight percent of the cases revealed intraepithelial neoplasm. There has been one recurrence with metastatic disease. The average follow-up period has been 56.8 months.


CONCLUSIONS
We advocate early recognition and excision with the Mohs technique with paraffin-embedded sections followed by reconstruction. The use of paraffin-embedded histologic sections helps with interpretation of intraepithelial and pagetoid tumor spread.
Yount
A B
AB
Mohs Cutaneous Surgery, Scripps Clinic and Research Foundation, La Jolla, California.
Bylund
D
D
Pratt
S G
SG
Greenway
H T
HT
D018266:Adenocarcinoma, Sebaceous / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005142:Eyelid Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D015580:Mohs Surgery