[Mechanisms of the modulating effect of mast cells on the leukocytic response in inflammation].
On the model of acute infectious peritonitis in rats with using the antagonists of the main biologic active products of mast cells it is shown that modulating effect of mast cells on the leucocytic reaction in inflammation is realized with the histamine, serotonin and heparin participation; in this way histamine influences mainly through H2-receptors on neutrophils and H1-receptors on monocytes.
Klimenko
N A
NA
Pyshnov
G Iu
GIu
D000818:Animals; D003533:Cyproheptadine; D004155:Diphenhydramine / Q000494:pharmacology; D007249:Inflammation / Q000276:immunology*; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000502:physiology*; D009000:Monocytes / Q000187:drug effects / Q000276:immunology*; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology*; D011479:Protamines / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
D011479:Protamines; D003533:Cyproheptadine; D004155:Diphenhydramine
Mekhanizmy moduliruiushchego vliianiia tuchnykh kletok na leĭkotsitarnuiu reaktsiiu pri vospalenii.