title: Destruction of the vesicoureteric plexus for the treatment of hypersensitive bladder disorders.
abstract: OBJECTIVE
  To determine whether bilateral vesicoureteric ganglion excision is effective in the treatment of women with hypersensitive bladder disorders.
  
  
  METHODS
  Utilizing neuroconductive studies, 175 women with hypersensitive bladder complaints of burning and frequency were selected by the presence of abnormal pudendal nerve sensory latency studies. Cystoscopy under anaesthesia revealed petechial haemorrhaging peritrigonally with bladder neck involvement, consistent with interstitial cystitis.
  
  
  RESULTS
  Laser obliteration of the vesicoureteric plexus bilaterally resulted in complete relief of pelvic pain in 112 patients and partial relief in 58. Forty-five patients with complete relief were followed for 2 years with no recurrence of symptoms. Complications included one case of periureteric fibrosis secondary to cauterization.
  
  
  CONCLUSIONS
  Bilateral vesicoureteric ganglion excision offers a new approach to treating hypersensitive bladder disorders such as interstitial cystitis.
authors.affiliation: Pelvic Pain Treatment Center, Women's Clinic for Interstitial Cystitis, Beverly Hills, California.
authors.forename: L
authors.initials: L
authors.lastname: Gillespie
mesh_terms: D017763:Autonomic Denervation / Q000379:methods*; D005260:Female; D006801:Humans; D006941:Hyperesthesia / Q000601:surgery*; D053685:Laser Therapy; D017773:Pelvic Floor; D017699:Pelvic Pain / Q000601:surgery; D011183:Postoperative Complications; D013562:Sympathectomy / Q000379:methods; D016896:Treatment Outcome; D014513:Ureter / Q000294:innervation; D001743:Urinary Bladder / Q000294:innervation; D001745:Urinary Bladder Diseases / Q000601:surgery*