Menkes' syndrome: wound healing in a long-term survivor.
A rare case of a long-term survivor of Menkes' syndrome who was treated early and had excision of bilateral axillary skin excess is presented. Primary wound healing was observed and skin histology showed fragmentation of the elastic fibers. Two years after surgery, the scars appeared atrophic with evidence of early recurrence of the skin excess. The relationship between Menkes' syndrome and the other copper-related syndromes (X-linked cutis laxa, occipital horn syndrome, and Ehlers-Danlos syndrome type 1X) is also described.
al-Qattan
M M
MM
Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
Thomson
H G
HG
D000293:Adolescent; D002921:Cicatrix / Q000473:pathology; D003483:Cutis Laxa / Q000473:pathology / Q000601:surgery*; D004547:Elastic Tissue / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D007706:Menkes Kinky Hair Syndrome / Q000473:pathology / Q000601:surgery*; D012867:Skin / Q000473:pathology; D013536:Suture Techniques; D014945:Wound Healing / Q000502:physiology*