Breast solitary schwannoma: fine-needle aspiration biopsy and immunocytochemical analysis.
A case of intramammary solitary schwannoma (SS) (benign neurilemoma) diagnosed by fine-needle aspiration biopsy (FNAB) and supported by immunocytochemical study is reported. The tumor arose in the right breast of an 18-yr-old woman and was clinically and radiologically considered a fibroadenoma. The smears obtained by FNAB of the lump showed clusters of spindle-shaped cells and suggested a benign mesenchymal neoplasm. The presence of some structures reminiscent of Verocay bodies and the immunocytochemical reactivity for S-100 protein antiserum demonstrated the schwannian nature of the tumor and suggested the diagnosis of SS. The final histologic examination confirmed the cytologic diagnosis.
Bernardello
F
F
Istituto di Anatomia ed Istologia Patologica, Università di Verona, Italy.
Caneva
A
A
Bresaola
E
E
Mombello
A
A
Zamboni
G
G
Bonetti
F
F
Iannucci
A
A
D000293:Adolescent; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D009442:Neurilemmoma / Q000737:chemistry / Q000473:pathology*; D011300:Preoperative Care