title: Cloning and sequence analysis of blaBIL-1, a plasmid-mediated class C beta-lactamase gene in Escherichia coli BS.
abstract: The extended-spectrum, plasmid-borne beta-lactamase gene blaBIL-1, which was discovered in Escherichia coli, has been cloned. Unusually for a plasmid-borne beta-lactamase, blaBIL-1 encodes a novel class C enzyme and appears to have originated from the chromosomal ampC gene of Citrobacter freundii.
authors.affiliation: SmithKline Beecham Pharmaceuticals, Brockham Park, Betchworth, Surrey, United Kingdom.
authors.forename: A P
authors.initials: AP
authors.lastname: Fosberry
authors.forename: D J
authors.initials: DJ
authors.lastname: Payne
authors.forename: E J
authors.initials: EJ
authors.lastname: Lawlor
authors.forename: J E
authors.initials: JE
authors.lastname: Hodgson
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D016971:Citrobacter freundii / Q000187:drug effects / Q000235:genetics; D003001:Cloning, Molecular; D016172:DNA Fingerprinting; D017931:DNA Primers; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005798:Genes, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics*; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D017931:DNA Primers; D001618:beta-Lactamases