title: [The isolation of capsule-free variants of Francisella tularensis].
abstract: New methods (selection in medium T with 20% Tween-80, inducing mutations leading to the appearance of resistance to triphenyl tetrazolium chloride or indoxyl phosphate) helped create a collection of F. tularensis stable non-capsular variants from strains of different subspecies. The characteristic features of all F. tularensis cap- variants include inability to serologic tests with erythrocytic diagnosticum, the absence of capsular antigens, sensitivity to normal human serum.
authors.forename: N V
authors.initials: NV
authors.lastname: Pavlovich
authors.forename: B N
authors.initials: BN
authors.lastname: Mishan'kin
authors.forename: G I
authors.initials: GI
authors.lastname: Danilevskaia
authors.forename: V A
authors.initials: VA
authors.lastname: Khodova
authors.forename: V V
authors.initials: VV
authors.lastname: Ryzhkova
authors.forename: M I
authors.initials: MI
authors.lastname: Tsimbalistova
authors.forename: V V
authors.initials: VV
authors.lastname: Sukhar'
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis; D016667:Bacterial Capsules / Q000276:immunology; D001431:Bacteriological Techniques; D003470:Culture Media; D005604:Francisella tularensis / Q000145:classification / Q000276:immunology / Q000302:isolation & purification* / Q000472:pathogenicity; D009154:Mutation; D010641:Phenotype; D012692:Serial Passage; D014774:Virulence
chemical_list: D000942:Antigens, Bacterial; D003470:Culture Media
vernacular_title: Poluchenie beskapsul'nykh variantov Francisella tularensis.