Effects of dietary supplementation of fructo-oligosaccharides on small intestinal bacterial overgrowth in dogs.
Sixteen IgA-deficient German Shepherd Dogs with small intestinal bacterial overgrowth were randomized into 2 groups. One group was fed a chicken-based kibble diet; the other was fed the same diet, but with 1% fructo-oligosaccharides supplemented at the expense of cornstarch. After being exposed to the diets for 46 to 51 days, the group that ate the supplemented diet had significantly (P = 0.04) fewer aerobic/facultative anaerobic bacterial colony-forming units in fluid from the duodenum/proximal part of the jejunum, as well as in the duodenal mucosa. We could not detect significant differences in the species of bacteria found in the intestine of these 2 groups of dogs. We conclude that at least some dietary carbohydrates can affect small intestinal bacterial populations in dogs with small intestinal bacterial overgrowth.
Willard
M D
MD
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843.
Simpson
R B
RB
Delles
E K
EK
Cohen
N D
ND
Fossum
T W
TW
Kolp
D
D
Reinhart
G
G
D000821:Animal Feed; D000818:Animals; D001420:Bacteria, Aerobic / Q000187:drug effects / Q000254:growth & development* / Q000302:isolation & purification; D001421:Bacteria, Anaerobic / Q000187:drug effects / Q000254:growth & development* / Q000302:isolation & purification; D004040:Dietary Carbohydrates; D004283:Dog Diseases; D004285:Dogs; D005260:Female; D005527:Food, Fortified; D005632:Fructose / Q000008:administration & dosage / Q000494:pharmacology*; D017098:IgA Deficiency / Q000382:microbiology / Q000662:veterinary*; D007583:Jejunum / Q000382:microbiology*; D008297:Male; D009844:Oligosaccharides / Q000008:administration & dosage / Q000494:pharmacology*; D009919:Orchiectomy; D010052:Ovariectomy
D004040:Dietary Carbohydrates; D009844:Oligosaccharides; D005632:Fructose