[Pemphigus chronicus benignus familiaris (Hailey-Hailey disease) and bipolar affective disease in 3 members of a family].
We report on three family members suffering from both autosomal dominant Hailey-Hailey disease and bipolar affective disorder. As molecular biology techniques have made the localization of genes causing simple Mendelian traits possible as a routine task, the gene for Hailey-Hailey disease will presumably be localized in the foreseeable future. The Hailey-Hailey gene and its chromosomal surrounding will then be a region of interest for linkage studies in bipolar affective disorder.
Wilk
M
M
Haut- und Poliklinik, Rheinisch-Westfälischen Friedrich-Wilhelms Universität Bonn.
Rietschel
M
M
Körner
J
J
Möller
H J
HJ
Nöthen
M M
MM
Bauer
R
R
Kreysel
H W
HW
D001706:Biopsy; D001714:Bipolar Disorder / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D002872:Chromosome Deletion; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D016506:Pemphigus, Benign Familial / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D012729:Sex Chromosome Aberrations / Q000175:diagnosis / Q000235:genetics*; D012867:Skin / Q000473:pathology; D014998:Y Chromosome
Pemphigus chronicus benignus familiaris (Morbus Hailey-Hailey) und bipolare affektive Erkrankung bei drei Mitgliedern einer Familie.