title: [Corneoscleral wound healing after self-sealing cataract surgery--1. Histological findings in the early postoperative period].
abstract: We investigated histologically wound adaptation and healing after self-sealing cataract surgery in rabbits in the early postoperative period. A scleral pocket (4 mm wide, 2 mm long) and an internal corneal flap (2 mm long) were made in one eye in a series of rabbits. After phacoemulsification, a balanced salt solution was injected to self-seal the wound (self-sealing group). After the same procedures were performed in the contralateral eye, a horizontal 9-0 nylon suture was placed in the wound (suture group). On the first day after operation, the adaptation of the wound was better in the suture group than in the self-sealing group. On the fourth day, the scleral wound space was filled with fibroblastic cells and fibrin-like substance, and activated keratocytes had accumulated along the corneal wound. Although inflammatory cells collected around the suture in the suture group, there was no remarkable difference between the two groups on the seventh day. These results indicated that the adaptation of the wound in the early period was different between the self-sealing group and the suture group, and that the difference might result in different peripheral corneal curvature. This might be one of the causes of the postoperative astigmatism in the early stage.
authors.affiliation: Department of Ophthalmology, Shinsuma Hospital, Hyogo-ken, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hirasaka
authors.forename: M
authors.initials: M
authors.lastname: Namiki
authors.forename: C
authors.initials: C
authors.lastname: Katakami
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
mesh_terms: D000818:Animals; D002387:Cataract Extraction / Q000379:methods; D003315:Cornea / Q000473:pathology; D065306:Corneal Injuries; D005260:Female; D011184:Postoperative Period; D011817:Rabbits; D012590:Sclera / Q000293:injuries* / Q000473:pathology; D014945:Wound Healing