title: Rifampicin in pneumococcal meningoencephalitis.
abstract: The cases are reported of two infants with pneumococcal meningitis in whom initial antibiotic treatment was ineffective despite the organisms being sensitive to the drugs used. A clinical and radiological diagnosis of meningoencephalitis was made. A rapid improvement followed the addition of rifampicin treatment.
authors.affiliation: Bristol Royal Hospital for Sick Children.
authors.forename: M J
authors.initials: MJ
authors.lastname: Peters
authors.forename: B L
authors.initials: BL
authors.lastname: Pizer
authors.forename: M
authors.initials: M
authors.lastname: Millar
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007769:Lactams; D008297:Male; D008590:Meningoencephalitis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000000981:diagnostic imaging / Q000188:drug therapy*; D012293:Rifampin / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D007769:Lactams; D012293:Rifampin