[Properties of glucocorticoid-sensitive alkaline proteinases of rat target organs].
The preliminary characterization of glucocorticoid-sensitive alkaline proteinases of rats thymus and liver was carried out. The role of active serine and cysteine residues in proteolysis was estimated. The influence of Ca++, Mg++, Fe++, Fe , Cu++, EDTA and EGTA on enzymes activity was studied. It is shown that the alkaline proteinases of thymus and liver have similar properties, but are not completely identical.
Ogurtsov
S I
SI
Dukhanin
A S
AS
Mitroshina
S Iu
SIu
D000818:Animals; D002413:Cations, Divalent; D003545:Cysteine / Q000378:metabolism; D003907:Dexamethasone / Q000031:analogs & derivatives* / Q000494:pharmacology; D004492:Edetic Acid; D004533:Egtazic Acid; D010450:Endopeptidases / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D008099:Liver / Q000201:enzymology*; D008297:Male; D051381:Rats; D012694:Serine / Q000378:metabolism; D013950:Thymus Gland / Q000201:enzymology*
D002413:Cations, Divalent; C004180:dexamethasone 21-phosphate; D012694:Serine; D004533:Egtazic Acid; D003907:Dexamethasone; D004492:Edetic Acid; D010450:Endopeptidases; D003545:Cysteine
Svoĭstva gliukokortikoid-chuvstvitel'nykh shchelochnykh proteinaz organov-misheneĭ krys.