title: The surgical anastomoses after orthotopic heart transplantation: clinical complications and morphologic observations.
abstract: From May 1984 through June 1993, 162 patients have undergone orthotopic heart transplantation at the University of Ottawa Heart Institute. Thirty-three deaths occurred, and postmortem examinations were performed in 29 of these cases. This study evaluated the surgical anastomoses of these patients' hearts, an aspect of orthotopic heart transplantation that has not been well described in the literature. The major findings encountered were two cases of stenosis at the left atrial anastomosis, one case of aortic anastomotic tear, one case of pulmonary artery anastomotic kinking, one case of left atrial suture line mural thrombus and possible coronary embolism, and one case of extramural compression of a coronary artery by an anastomotic suture. Other findings when the suture lines were examined included residual native valve remnants, protruding tissue tags or other tissue remnants, mural thrombi, and protruding free suture ends. These findings are described, illustrated, and discussed in the context of the published literature on the subject.
authors.affiliation: Department of Pathology, University of Ottawa, Ontario, Canada.
authors.forename: A L
authors.initials: AL
authors.lastname: Wolfsohn
authors.forename: V M
authors.initials: VM
authors.lastname: Walley
authors.forename: R G
authors.initials: RG
authors.lastname: Masters
authors.forename: R A
authors.initials: RA
authors.lastname: Davies
authors.forename: S A
authors.initials: SA
authors.lastname: Boone
authors.forename: W J
authors.initials: WJ
authors.lastname: Keon
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical / Q000009:adverse effects; D001011:Aorta / Q000473:pathology / Q000601:surgery; D002423:Cause of Death; D003251:Constriction, Pathologic / Q000209:etiology / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006325:Heart Atria / Q000473:pathology / Q000601:surgery; D006331:Heart Diseases / Q000209:etiology / Q000473:pathology; D016027:Heart Transplantation / Q000009:adverse effects / Q000473:pathology*; D006470:Hemorrhage / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D011651:Pulmonary Artery / Q000473:pathology / Q000601:surgery; D015996:Survival Rate; D013927:Thrombosis / Q000209:etiology / Q000473:pathology; D013997:Time Factors