[The isolation of capsule-free variants of Francisella tularensis].
New methods (selection in medium T with 20% Tween-80, inducing mutations leading to the appearance of resistance to triphenyl tetrazolium chloride or indoxyl phosphate) helped create a collection of F. tularensis stable non-capsular variants from strains of different subspecies. The characteristic features of all F. tularensis cap- variants include inability to serologic tests with erythrocytic diagnosticum, the absence of capsular antigens, sensitivity to normal human serum.
Pavlovich
N V
NV
Mishan'kin
B N
BN
Danilevskaia
G I
GI
Khodova
V A
VA
Ryzhkova
V V
VV
Tsimbalistova
M I
MI
Sukhar'
V V
VV
D000942:Antigens, Bacterial / Q000032:analysis; D016667:Bacterial Capsules / Q000276:immunology; D001431:Bacteriological Techniques; D003470:Culture Media; D005604:Francisella tularensis / Q000145:classification / Q000276:immunology / Q000302:isolation & purification* / Q000472:pathogenicity; D009154:Mutation; D010641:Phenotype; D012692:Serial Passage; D014774:Virulence
D000942:Antigens, Bacterial; D003470:Culture Media
Poluchenie beskapsul'nykh variantov Francisella tularensis.