[Successful pregnancy after allogeneic bone marrow transplantation: two case reports].
A case of successful pregnancy after allogeneic bone marrow transplantation (BMT) in a woman with severe aplastic anemia conditioned with 200 mg/kg cyclophosphamide and 4.5 Gy total lymphoid irradiation (TLI) at the age of 15 years is reported. She delivered a normal child 92 months after BMT. A male with paroxysmal nocturnal hemoglobinuria received allogeneic BMT at the age of 22 years is described as a second case. He was conditioned with 200 mg/kg CY and 7.5 Gy TLI and parented a normal child 32 months after BMT. These observations demonstrate that normal pregnancy can follow high dose chemotherapy and TLI.
Hirabayashi
N
N
Department of Hematology, Nagoya Daini Red Cross Hospital.
Goto
S
S
Isogai
C
C
Tomita
A
A
Ohno
T
T
D000293:Adolescent; D000328:Adult; D000741:Anemia, Aplastic / Q000628:therapy; D016026:Bone Marrow Transplantation; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D014184:Transplantation, Homologous