[Influence of ionized calcium concentration during cardiopulmonary bypass on pediatric cardiac surgery].
Changes of serum ionized calcium concentration (Ca2+) during cardiopulmonary bypass (CPB) were analyzed in 30 pediatric cardiac patients less than 15 kg body weight. Ca2+ decreased suddenly after the start of CPB, and it gradually increased to the normal value. Citrate added to the stored blood for priming and its metabolism might play a role in these changes of Ca2+. Addition of adequate volume of calcium chloride to the priming prevented sudden decrease of Ca2+. Although addition of citrate before aortic declamp effectively decreased Ca2+ and may prevent reperfusion cardiac injury associated with hypercalcemia, there were no correlation between predeclamp level of Ca2+ and serum CPK and GOT levels.
Atsumi
N
N
Department of Surgery, University of Tsukuba, Japan.
Abe
M
M
Sakakibara
Y
Y
Terada
Y
Y
Jikuya
T
T
Tsutsui
T
T
Okamura
K
K
Mitsui
T
T
Hori
M
M
D001835:Body Weight; D002118:Calcium / Q000097:blood*; D002122:Calcium Chloride / Q000008:administration & dosage; D002315:Cardiopulmonary Bypass; D002951:Citrates / Q000008:administration & dosage / Q000097:blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control
D002951:Citrates; D002122:Calcium Chloride; D002118:Calcium