title: Burden of disability in a post war birth cohort in the UK.
abstract: OBJECTIVE
  To report the prevalence of physical disability in a national sample of 43 year old men and women, and examine the relationship between disability and the consumption of hospital care. To assess the contribution of childhood health and social circumstances to the risk of adult disability, and the socioeconomic consequences of disability.
  
  
  METHODS
  The assessment of disabilities of physical movement was based on criteria developed by OPCS for their national survey of disability. The analysis used data on socioeconomic circumstances from childhood to 43 years and on serious illness in the first 25 years of life collected prospectively on members of the MRC National Survey of Health and Development, the 1946 birth cohort study.
  
  
  METHODS
  England, Wales, and Scotland.
  
  
  METHODS
  A general population sample of 3235 men and women aged 43 years.
  
  
  RESULTS
  Seven per cent of cohort survivors at 43 years were physically disabled and a further 3% reported difficulties although they were not assessed as disabled according to OPCS criteria. The prevalence of severe disability at this age was similar to that derived from the OPCS survey but the prevalence of mild disability was substantially greater. Disability was associated with a greater use of hospital care in recent years and throughout life. Those who had experienced a serious illness in earlier life were over twice as likely to be disabled; certain conditions, such as polio, were associated with a particularly high relative risk. Those who had had a socially disadvantaged start to life were more likely to be physically disabled at 43 years but the strength of this relationship was considerably weakened by adjustment for later social factors, suggesting that social disadvantage throughout life, or during adult life, increased the risk of disability. Taking these results into account the relative impact of disability on income and employment was found to be greatest for those from the unskilled and semi-skilled classes.
  
  
  CONCLUSIONS
  The prevalence of physical disability among those in early middle age may be greater than previously estimated. The strong links between childhood ill health and adult disability and its association with high levels of hospital care support longstanding recommendations for better coordination between child and adult health services. Social disadvantages affects the risk of disability and its financial and employment consequences.
authors.affiliation: University College, London Medical School, Department of Epidemiology and Public Health.
authors.forename: D J
authors.initials: DJ
authors.lastname: Kuh
authors.forename: M E
authors.initials: ME
authors.lastname: Wadsworth
authors.forename: E J
authors.initials: EJ
authors.lastname: Yusuf
mesh_terms: D000328:Adult; D017668:Age of Onset; D015331:Cohort Studies; D017281:Cost of Illness; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D004194:Disease; D004651:Employment; D005260:Female; D006761:Hospitals / Q000706:statistics & numerical data*; D006801:Humans; D007182:Income; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D012959:Socioeconomic Factors; D017741:Survivors; D006113:United Kingdom / Q000453:epidemiology