title: Radiotracer measurement of ureteric blood flow.
abstract: This paper describes a novel technique using the blood flow tracer C14-iodoantipyrine to measure ureteric blood flow in anesthetized Sprague-Dawley rats. The ureters were divided into five equal segments, and the blood flow was measured using a modification of the Fick principle. There was a gradient down the ureter with a significant difference between upper (159 ml./100 gm./min.) and lower (83 ml./100 gm./min.) ureteric segmental blood flows. This technique may allow the role of ureteric ischemia to be investigated in a variety of disease states.
authors.affiliation: Surgical Professorial Unit, Mater Misericordiae Hospital, Dublin, Ireland.
authors.forename: E F
authors.initials: EF
authors.lastname: Mooney
authors.forename: J G
authors.initials: JG
authors.lastname: Geraghty
authors.forename: M
authors.initials: M
authors.lastname: O'Connell
authors.forename: P
authors.initials: P
authors.lastname: Kent
authors.forename: W
authors.initials: W
authors.lastname: Angerson
authors.forename: A
authors.initials: A
authors.lastname: Quereshi
authors.forename: A
authors.initials: A
authors.lastname: Sarazen
authors.forename: J M
authors.initials: JM
authors.lastname: Fitzpatrick
mesh_terms: D000818:Animals; D000983:Antipyrine / Q000031:analogs & derivatives; D002250:Carbon Radioisotopes; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D014513:Ureter / Q000098:blood supply*
chemical_list: D002250:Carbon Radioisotopes; D000983:Antipyrine; C008135:iodoantipyrine