title: Fixation with biodegradable devices of acetabular components in a canine model.
abstract: Cementless total hip arthroplasty was performed in 13 dogs. The acetabular component was anchored with two biodegradable devices (polylactic acid) in seven dogs and with two titanium screws in six dogs. At 14 weeks, histomorphometric determinations of bony ingrowth into the porous coating of the acetabular weight bearing dome was 54.4% when fixed with the biodegradable devices and 58.9% when fixed with the titanium screws (no statistically significant difference; p = 0.556). At the sites of fixation, less bony ingrowth occurred with the biodegradable devices. The use of biodegradable devices in total hip arthroplasty should overcome the potential metal corrosion of titanium screws that can lead to polyethylene wear.
authors.affiliation: Division of Orthopaedic Surgery, Toronto Hospital, University of Toronto, Ontario, Canada.
authors.forename: N Y
authors.initials: NY
authors.lastname: Otsuka
authors.forename: A G
authors.initials: AG
authors.lastname: Binnington
authors.forename: V L
authors.initials: VL
authors.lastname: Fornasier
authors.forename: J R
authors.initials: JR
authors.lastname: Davey
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D003692:Delayed-Action Preparations; D004285:Dogs; D006622:Hip Prosthesis; D007773:Lactates; D019344:Lactic Acid; D008297:Male; D009984:Orthopedic Fixation Devices; D016348:Osseointegration; D011091:Polyesters; D011108:Polymers; D011474:Prosthesis Design
chemical_list: D001672:Biocompatible Materials; D003692:Delayed-Action Preparations; D007773:Lactates; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)