New support for a folk remedy: cranberry juice reduces bacteriuria and pyuria in elderly women.
Cranberry juice has developed a following as a simple, nonpharmacologic means to reduce or treat urinary tract infections, yet the scientific basis for such a claim has been lacking. A new study suggests that bacterial infections (bacteriuria) and associated influx of white blood cells into the urine (pyuria) can be reduced by nearly 50% in elderly women who drink 300 mL of cranberry juice cocktail each day over the course of a 6-month study. The results of this study suggest that consumption of cranberry juice is more effective in treating than preventing bacteriuria and pyuria. Along with earlier reports on the ability of cranberry juice to inhibit bacterial adherence to urinary epithelial cells in cell culture, this new work suggests that drinking cranberry juice each day may be clinically useful. Additional work must be conducted, however, to more completely define the efficacy of cranberry juice.
Fleet
J C
JC
Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111.
D000368:Aged; D001437:Bacteriuria / Q000628:therapy*; D001628:Beverages; D004311:Double-Blind Method; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D005638:Fruit; D006801:Humans; D008519:Medicine, Traditional; D011776:Pyuria / Q000628:therapy*