title: [Clinical and experimental research of buyang huanwu tang granule in treatment of ischemic apoplexy].
abstract: 38 cases of ischemic apoplexy were randomly divided into three groups. Among them 26 cases were treated with type I and type III of Buyang Huanwu Tang Granule (BYHWTG) for 10 weeks, respectively. The other 12 cases served as a control group. The results showed that clinical cure and markedly effective rate were 42.3%, the total effective rate was 88.5% in BYHWTG group. The effective rate of BYHWTG type I for the treatment of ischemic apoplexy was 100% and it was superior to type III (84.6). BYHWTG could significantly improve hemorheologic indexes in the patients of ischemic apoplexy. The activity of RBC sodium pump was markedly raised from 0.210 +/- 0.003 to 0.250 +/- 0.008 1/h (P < 0.001) in BYHWTG type I. The results of this study suggested that BYHWTG had evident efficacy in the treatment of ischemic apoplexy.
authors.affiliation: Institute of the Integration of TCM-WM, Shanghai Medical University.
authors.forename: L L
authors.initials: LL
authors.lastname: Zha
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Shen
authors.forename: P
authors.initials: P
authors.lastname: Zhang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001809:Blood Viscosity / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects; D012964:Sodium / Q000097:blood; D000254:Sodium-Potassium-Exchanging ATPase / Q000187:drug effects
chemical_list: D004365:Drugs, Chinese Herbal; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase