Photoinactivated lymphocyte therapy of cutaneous T-cell lymphoma.
The unique aspects of this therapy are presented in this article to provide background information critical to understanding the clinical results, which are then presented. The laboratory models discussed in the later parts of this article demonstrate the dependence of this response on the photoinactivation of lymphocytes by 8-methoxypsoralen in the presence of ultraviolet-A light.
Heald
P
P
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.
Knobler
R
R
LaRoche
L
L
D001804:Blood Transfusion, Autologous; D006801:Humans; D017710:Lymphocyte Transfusion; D016410:Lymphoma, T-Cell, Cutaneous / Q000473:pathology / Q000628:therapy*; D011701:PUVA Therapy; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000628:therapy*