GI amyloidosis treated with megadoses of i.v. gammaglobulin.
A 50-year-old-man with peripheral edema and muscle cramps without proteinuria as presenting symptoms was found to have hypoproteinemia due to amyloidosis of the stomach. After failure to control the symptoms with diuretics, oral calcium supplement and colchicine, large doses of intact gamma-globulin (250 mg/kg bodyweight, total, 3 separate infusions every other day) infused i.v., helped to control the symptoms for more than 8 months.
Krastev
Z
Z
Clinic of Gastroenterology, Faculty of Medicine, Sofia, Bulgaria.
Vassilev
M
M
D000686:Amyloidosis / Q000150:complications / Q000628:therapy*; D006801:Humans; D007019:Hypoproteinemia / Q000209:etiology; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013272:Stomach Diseases / Q000150:complications / Q000628:therapy*
D016756:Immunoglobulins, Intravenous