title: MRI of malignant fibrous histiocytoma of soft tissue: analysis of 13 cases with pathologic correlation.
abstract: We reviewed the magnetic resonance (MR) appearances of 13 malignant fibrous histiocytomas (MFH) of soft tissue and correlated each with the respective lesion's histopathology. The MR images were evaluated for signal intensity on T1- and T2-weighted spin echo sequences, homogeneity of the lesion, presence of internal low signal septations, and margin definition. Histologic subtypes of MFH included storiform-pleomorphic, giant cell, myxoid, and inflammatory. We could not establish a correlation between MR appearance and histopathology. Instead, our series exhibited general features suggestive of malignant soft tissue neoplasms, namely poor margin definition, internal low signal septation, and heterogeneous high signal intensity on T2-weighted images.
authors.affiliation: Department of Radiology, Mount Sinai Medical Center of the City University New York, New York.
authors.forename: T T
authors.initials: TT
authors.lastname: Miller
authors.forename: G
authors.initials: G
authors.lastname: Hermann
authors.forename: I F
authors.initials: IF
authors.lastname: Abdelwahab
authors.forename: M J
authors.initials: MJ
authors.lastname: Klein
authors.forename: S
authors.initials: S
authors.lastname: Kenan
authors.forename: M M
authors.initials: MM
authors.lastname: Lewis
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology