Prevalence of previously undetected osteonecrosis of the femoral head in renal transplant recipients.
OBJECTIVE
To determine the prevalence of osteonecrosis (ON) of the femoral head in renal transplant recipients and determine the natural history of previously undetected lesions.


METHODS
The hips of 132 renal transplant recipients were examined with magnetic resonance (MR) imaging, with radiographs obtained only in the patients with positive MR images.


RESULTS
Ten patients (15 hips) were considered to have ON (prevalence, 7.6%). Eleven of the hips had Ficat stage 0 disease (asymptomatic, preradiographic) and were followed up with serial radiography and MR imaging. Over an average follow-up of 22 months, only one of these lesions showed progression. The other 10 hips did not show progression at MR imaging or radiography.


CONCLUSIONS
Previously undetected ON may have a benign course in many cases. Although a substantial number of patients have previously unsuspected disease, further study is necessary to assess the need for "prophylactic" surgery in such cases.
Mulliken
B D
BD
Department of Orthopaedic Surgery, University of Iowa, Iowa City 52242.
Renfrew
D L
DL
Brand
R A
RA
Whitten
C G
CG
D000328:Adult; D005260:Female; D005271:Femur Head Necrosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography