title: [Effect of a sublethal dose of sodium nitrite on respiration and oxidative phosphorylation in the rat liver mitochondria].
abstract: A sublethal dose of sodium nitrates (60 mg/kg) 30 min after intraperitoneal administration to rats increases ADP-stimulated respiration, when succinate is used as the substrate. Its stimulating action is associated with an increase of efficiency of oxygen utilization. Intraperitoneal administration of succinic acid in a dose of 25 mg/kg normalizes changes induced by nitrites. Stress and hypoxic factors in the action of nitrites on aerobic processes in mitochondria are discussed.
authors.forename: A M
authors.initials: AM
authors.lastname: Babs'kyĭ
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Stefankiv
authors.forename: V M
authors.initials: VM
authors.lastname: Korobov
mesh_terms: D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D000860:Hypoxia / Q000503:physiopathology*; D007928:Lethal Dose 50; D008930:Mitochondria, Liver / Q000187:drug effects*; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects*; D051381:Rats; D012977:Sodium Nitrite / Q000494:pharmacology*; D013312:Stress, Physiological / Q000503:physiopathology*; D013386:Succinates / Q000494:pharmacology; D019802:Succinic Acid
chemical_list: D013386:Succinates; D000244:Adenosine Diphosphate; D019802:Succinic Acid; D012977:Sodium Nitrite
vernacular_title: Vplyv subletal'noï dozy nitrytu natriiu na dykhannia ta okysniuval'ne fosforyliuvannia u mitokhondriiakh pechinky shchura.