[Adjuvant treatment with mitomycin eyedrops after pterygium excision: Ticino experience].
OBJECTIVE
Prospective pilot-study in the canton of Ticino to evaluate the prevention of recurrence of pterygium after excision and mitomycin drops.


METHODS
Mitomycin 0.02% drops have been used from 6 to 10 days after 24 cases of corneoscleral excision of the pterygium.


RESULTS
After a mean observation time of 13 months, we did not see any recurrence. The vision was improved in 8 eyes over 21, was unchanged in 15 eyes and deteriorated in 1 eye due to unrelated causes. In two cases we observed a thinning of 0.3 mm deep over 1 mm2 of the sclera.


CONCLUSIONS
The rate of recurrence after excision of the pterygium and followed by instillation of mitomycin drops is lower than the other described treatments. However, complications described in literature, yet not observed in our own study, underline the necessity of a prolonged perspective study.
Simona
F
F
Anastasi-Forni
C
C
Benedetti
C
C
Failla
F G
FG
Rossi
F M
FM
Meyer
U
U
D000328:Adult; D000368:Aged; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003315:Cornea / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008937:Mitomycins / Q000008:administration & dosage* / Q000009:adverse effects; D009883:Ophthalmic Solutions; D011625:Pterygium / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D012008:Recurrence; D012590:Sclera / Q000473:pathology / Q000601:surgery; D014792:Visual Acuity / Q000187:drug effects
D008937:Mitomycins; D009883:Ophthalmic Solutions
Le traitment adjonctif par un collyre de mitomycine après excision du ptérygion: l'expérience tessinoise.