title: [Influence of chronic intoxication with phospho-organic insecticide dimethoate on the hemopoietic system in rats].
abstract: Toxic effect of insecticide dimethoate applied to 400 rats for two years in concentrations of 2 to 200 mg/kg fodder was investigated. During the last six months of observation the toxic influence of the larger doses of this preparation was manifested by a higher mortality of the animals. Neither disadvantageous influence upon the maturation of each individual haemopoietic series, nor action inducing pathologic proliferation in the haemopoietic system of rats were found.
authors.affiliation: IV Katedry i Kliniki Chorób Wewnetrznych Sl. AM w Katowicach.
authors.forename: G
authors.initials: G
authors.lastname: Jonderko
authors.forename: M
authors.initials: M
authors.lastname: Polko
authors.forename: K
authors.initials: K
authors.lastname: Kita
authors.forename: R
authors.initials: R
authors.lastname: Knapek
authors.forename: S
authors.initials: S
authors.lastname: Kobes
authors.forename: P
authors.initials: P
authors.lastname: Kotyla
mesh_terms: D000818:Animals; D004117:Dimethoate / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006410:Hematopoiesis / Q000187:drug effects*; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004117:Dimethoate
vernacular_title: Badania wpływu przewlekłego zatrucia insektycydem fosforoorganicznym dimetoat na układ krwiotwórczy u szczurów.