[Effect of reserpine on grooming parameters in rats].
The analysis of data of the graphic registration of grooming showed that prolonged injections of reserpine (2.5 mg/kg of weight) induce phasic changes on the stereotype grooming movements. During the period when the noradrenergic influence is pronounced (the 1st day of injection of reserpine) grooming movements are inhibited, their duration is diminished, especially of washing movements. During the period when the noradrenergic influence is weakened (the 2nd and the 3rd days after injections) grooming movements are activated and the duration of every movement is prolonged; moreover, they unite into long "chains" of movements. During the period when dopaminergic influence is weakened (the 4th and the 5th days) tremor ensues, grooming is depressed except for "shaking-down" movements whose quantity and duration increase. Reserpine does not influence in any noticeable degree on h the frequency of grooming movements of adult rats.
Lepekhina
L M
LM
D000818:Animals; D006120:Grooming / Q000187:drug effects*; D008297:Male; D009474:Neurons / Q000502:physiology; D009638:Norepinephrine / Q000502:physiology; D051381:Rats; D012110:Reserpine / Q000494:pharmacology*; D013239:Stereotyped Behavior / Q000187:drug effects
D012110:Reserpine; D009638:Norepinephrine
Vliianie rezerpina na parametry gruminga krys.