[Spectrum of DNA haplotypes and beta-thalassemia mutations linked with them in the Azerbaijan Republic].
Haplotyping of the beta-globin gene cluster was performed on DNA samples from 110 Azerbaidzhanian beta-thalassemic patients and their families. During this study, we found 18 different haplotypes and determined the frequency of their occurrence. Nine of these haplotypes have never been observed earlier in the studied population. One of the haplotypes was found only in beta-thalassemia alleles. Several haplotypes were associated with beta-thalassemia mutations found earlier in Azerbaidzhan.
Tagiev
A F
AF
Surin
V L
VL
Luk'ianenko
A V
AV
Kulieva
E A
EA
Mamedova
T A
TA
Solov'ev
G Ia
GIa
D001382:Azerbaijan / Q000453:epidemiology; D004247:DNA / Q000235:genetics*; D008040:Genetic Linkage; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D009154:Mutation; D017086:beta-Thalassemia / Q000453:epidemiology / Q000235:genetics*
D004247:DNA
Spektr DNK-gaplotipov i stseplennye s nimi beta-talassemicheskie mutatsii v Azerbaĭdzhanskoĭ respublike.