title: Cell polarity in early C. elegans development.
abstract: The polarization of the embryonic axes is a key event in embryogenesis, being one of the earliest manifestations of the shape and form of the organism. The acquisition of polarity by individual blastomeres is one of the earliest indicators of commitment to a particular pathway of differentiation. These phenomena have been studied in the development of C. elegans both at the cellular and organismal level. This review summarizes what is known about how polarity is established in the blastomeres of this organism, how the division axes of polarized cells are determined, and how the embryonic axes are set up.
authors.affiliation: MRC Laboratory of Molecular Biology, Cambridge, England.
authors.forename: B
authors.initials: B
authors.lastname: Goldstein
authors.forename: S N
authors.initials: SN
authors.lastname: Hird
authors.forename: J G
authors.initials: JG
authors.lastname: White
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000502:physiology*; D017173:Caenorhabditis elegans / Q000196:embryology*; D016764:Cell Polarity / Q000502:physiology*; D015053:Zygote / Q000502:physiology