Biochemical aspects of biosensors.
A review of the major types of biological molecules and systems (including antibodies, enzymes and whole cells) on which biosensors can be based is presented. Specific emphasis is placed on a critical assessment of the relative strengths and weaknesses of the respective technologies and on analysis of the importance of practical considerations such as sample interference, signal-to-noise ratio and biomolecule stability. The importance of efficient coupling of the biological and transducer components of a biosensor is highlighted. Future trends and directions in biosensor research and commercial aspects of the technology are also discussed. The article concludes with a summary of current biosensor research activities at the GEC-Marconi Hirst Research Centre.
Byfield
M P
MP
Hirst Research Centre, Herts, UK.
Abuknesha
R A
RA
D000818:Animals; D015374:Biosensing Techniques; D006801:Humans