title: Paroxetine treatment of premature ejaculation: a double-blind, randomized, placebo-controlled study.
abstract: Seventeen male outpatients with premature ejaculation were randomly assigned to treatment with paroxetine (N = 8) or placebo (N = 9). After a first week dose of 20 mg/day, the paroxetine regimen was increased to 40 mg/day for 5 weeks. Patients and their female partners were interviewed separately. Patients treated with paroxetine had significantly greater clinical improvement than the patients given placebo.
authors.affiliation: Outpatient Department of Psychiatry, Leyenburg Hospital, The Hague, The Netherlands.
authors.forename: M D
authors.initials: MD
authors.lastname: Waldinger
authors.forename: M W
authors.initials: MW
authors.lastname: Hengeveld
authors.forename: A H
authors.initials: AH
authors.lastname: Zwinderman
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D004542:Ejaculation / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017374:Paroxetine / Q000008:administration & dosage / Q000627:therapeutic use*; D010919:Placebos; D020018:Sexual Dysfunctions, Psychological / Q000188:drug therapy* / Q000523:psychology; D016896:Treatment Outcome
chemical_list: D010919:Placebos; D017374:Paroxetine