title: Severe aplastic anaemia--an aetiological correlation.
abstract: Over 4 years, 43 cases of severe aplastic anaemia (SAA) were seen. Etiologically 58.1% had idiopathic, 39.5% secondary and 2.3% congenital aplastic, anaemia. Idiopathic SAA was more common in patients between 0-15 years of age, whereas secondary SAA was more frequent in 16-60 years age group. Males were more commonly affected with a male:female ratio of 3.3:1. Amongst 17 cases of secondary SAA, chloramphenicol was responsible for 4, septran for 3, insecticides for 2 and anti-scabitic drugs, anti-diabetic drugs and "kushta from hakeem" in one patient each. Hepatitis associated SAA was suspected in 3 cases.
authors.affiliation: Department of Haematology, Rawalpindi Medical College.
authors.forename: K
authors.initials: K
authors.lastname: Hassan
authors.forename: N
authors.initials: N
authors.lastname: Ikram
authors.forename: M J
authors.initials: MJ
authors.lastname: Akhtar
authors.forename: M
authors.initials: M
authors.lastname: Tahir
authors.forename: T A
authors.initials: TA
authors.lastname: Bhatti
authors.forename: M
authors.initials: M
authors.lastname: Hassan
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000741:Anemia, Aplastic / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006505:Hepatitis / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D017678:Sex Distribution