Aberrant reinnervation following hypoglossal nerve damage.
Hypoglossal nerve damage is a known complication of carotid endarterectomy, occurring in approximately 5% of endarterectomies. The vast majority of these patients recover without functional disability from this injury even if the tongue remains hemiplegic. We report 2 patients who suffered hypoglossal nerve section during neck surgery. Although they were initially mildly symptomatic, they developed increasingly severe dysarthria and dysphagia beginning 4 months after surgery. EMG revealed abnormal coactivation of the genioglossus and styloglossus muscles on the affected side, suggesting aberrant reinnervation. Aberrant reinnervation is a well-known complication of facial nerve injury, but has not been previously recognized in hypoglossal nerve injury. Like the face, the tongue is composed of many muscles that must perform complex movements. Normally, injury to one hypoglossal nerve causes little or no disability, but when aberrant reinnervation occurs, the tongue no longer moves in a coordinated manner, and significant dysarthria ensues.
Wilson
J R
JR
Louisiana State University Medical Center, Department of Neurology, New Orleans 70112.
Sumner
A J
AJ
Eichelman
J
J
D000368:Aged; D001284:Atrophy; D004401:Dysarthria / Q000209:etiology*; D016894:Endarterectomy, Carotid / Q000009:adverse effects; D005152:Facial Muscles / Q000294:innervation* / Q000503:physiopathology; D005260:Female; D006801:Humans; D061228:Hypoglossal Nerve Injuries; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013363:Submandibular Gland / Q000601:surgery; D014059:Tongue / Q000294:innervation* / Q000473:pathology