[Liposomes in the combined treatment of patients with chronic obstructive bronchitis].
Liposome inhalation was included into intensive combined treatment of 78 patients with chronic bronchitis exacerbation and preasthma. As shown by investigations of respiration, central hemodynamics, lipid and protein metabolism, vitamin E concentration, chemiluminescence before, during and after treatment, liposomes promote elimination of obstruction in the airways, pO2 normalization, correction of impaired lipid and protein metabolism, an increase in vitamin E level in peripheral blood leading to antioxidant system recovery and inhibition of lipid peroxidation. The use of lipin reduces the time of treatment of bronchitis chronics 2-fold. Lipin proved also to display a cardioprotective action.
Novikova
R I
RI
Chernyĭ
V I
VI
Stefanov
A V
AV
Akhlamova
Iu I
IuI
D000280:Administration, Inhalation; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D001798:Blood Proteins / Q000187:drug effects / Q000378:metabolism; D001991:Bronchitis / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D003422:Critical Care / Q000379:methods; D004337:Drug Carriers; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008055:Lipids / Q000097:blood; D008081:Liposomes; D009930:Organic Chemicals; D012119:Respiration / Q000187:drug effects; D014810:Vitamin E / Q000097:blood
D000890:Anti-Infective Agents; D001798:Blood Proteins; D004337:Drug Carriers; D008055:Lipids; D008081:Liposomes; D009930:Organic Chemicals; C088310:lipine; D014810:Vitamin E
Liposomy v kompleksnom lechenii bol'nykh s khronicheskim obstruktivnym bronkhitom.