[Decrease in constrictor response and increase in dilator response of the resistant artery in experimental myocardial infarction: effect of adaptation to hypoxia on this phenomenon].
After adaptation to hypoxia experimental myocardial infarction does not result in enhanced vasodilatory responses of isolated tail artery from rat to acetylcholine and isoproterenol. At the same time the vascular reactivity to norepinephrine and phenylephrine is enhanced. These data may explain the previously described improvement in postinfarction time course of the blood pressure due to preliminary adaptation to hypoxia.
Meerson
F Z
FZ
Mashina
S Iu
SIu
Lapshin
A V
AV
Manukhina
E B
EB
D000222:Adaptation, Physiological; D000818:Animals; D003331:Coronary Vessels; D000860:Hypoxia / Q000150:complications / Q000503:physiopathology*; D066298:In Vitro Techniques; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D014661:Vasoconstriction / Q000502:physiology*; D014664:Vasodilation / Q000502:physiology*
Umen'shenie konstriktornykh i uvelichenie dilatatornykh reaktsiĭ rezistivnoĭ arterii pri éksperimental'nom infarkte miokarda, vliianie adaptatsii k gipoksii na étot fenomen.