title: Experience with radical esophagogastric devascularization procedures (Sugiura) for variceal bleeding outside Japan.
abstract: The Sugiura operation has been reported to have low operative mortality, rebleeding, and encephalopathy rates when carried out in a predominantly nonalcoholic Japanese population with good liver function. A literature review of reports of the Sugiura procedure outside Japan reveals a high complication and mortality rate when it is used as an emergency procedure in patients with advanced liver disease, especially in those with alcoholic cirrhosis. Uncontrolled studies report results that differ little from the Japanese series when the operation is confined to good-risk patients in the elective situation. Our experience with the Sugiura operation supports its role in these circumstances, especially in patients with portal vein thrombosis and normal liver function. The only good prospective controlled trial has been carried out in patients with schistosomiasis and suggests that the Sugiura operation is far superior to total shunt and may have a slight advantage over the Warren shunt because of its low incidence of postoperative encephalopathy. More controlled trials are required to establish its role in good- to moderate-risk patients with alcoholic cirrhosis.
authors.affiliation: Department of Surgery, University of Toronto, Ontario, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Dagenais
authors.forename: B
authors.initials: B
authors.lastname: Langer
authors.forename: B R
authors.initials: BR
authors.lastname: Taylor
authors.forename: P D
authors.initials: PD
authors.lastname: Greig
mesh_terms: D000328:Adult; D000368:Aged; D001158:Arteries / Q000601:surgery; D002986:Clinical Trials as Topic; D003431:Cross-Cultural Comparison; D004932:Esophageal and Gastric Varices / Q000401:mortality / Q000601:surgery*; D004947:Esophagus / Q000098:blood supply*; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000401:mortality / Q000601:surgery*; D006801:Humans; D006975:Hypertension, Portal / Q000401:mortality / Q000601:surgery*; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009864:Ontario; D011183:Postoperative Complications / Q000401:mortality; D012008:Recurrence; D014680:Veins / Q000601:surgery