Extending a Bayesian analysis of the two-period crossover to allow for baseline measurements.
In the context of a two-period crossover study with baseline measurements a graphical method is developed for displaying the dependence of posterior inferences concerning the treatment effect on unavoidable prior beliefs about the 'correct' model. The method is a generalization of the approach developed by Grieve for the corresponding case without baselines.
Grieve
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AP
Safety of Medicines Department, ZENECA Pharmaceuticals, Macclesfield, Cheshire, U.K.
D000279:Administration, Cutaneous; D000284:Administration, Oral; D000787:Angina Pectoris / Q000188:drug therapy; D001499:Bayes Theorem; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D003692:Delayed-Action Preparations; D006801:Humans; D007548:Isosorbide Dinitrate / Q000008:administration & dosage; D015233:Models, Statistical; D005996:Nitroglycerin / Q000008:administration & dosage; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*; D016896:Treatment Outcome
D003692:Delayed-Action Preparations; D005996:Nitroglycerin; D007548:Isosorbide Dinitrate