Salivary theophylline concentrations in neonates.
Salivary theophylline concentrations in neonates were measured by a homogeneous enzyme immunoassay and compared with serum concentrations. Free serum theophylline concentrations were also compared with salivary concentrations and the values obtained were almost identical. Results using the immunoassay agreed well with those obtained using a high-performance liquid chromatographic procedure (HPLC).
Thompson
S J
SJ
Department of Clinical Biochemistry, King's College Hospital, Denmark Hill, London, UK.
D002851:Chromatography, High Pressure Liquid; D006801:Humans; D007124:Immunoenzyme Techniques; D007231:Infant, Newborn; D012016:Reference Values; D015203:Reproducibility of Results; D012463:Saliva / Q000737:chemistry*; D013806:Theophylline / Q000032:analysis* / Q000097:blood
D013806:Theophylline