title: [The epidemiological diagnosis of "fecal-oral" hepatitis E in Tajikistan].
abstract: On the basis of the results of the retrospective epidemiological analysis of hepatitis A morbidity for many years in the Leninabad (now Hojend) region of Tajikistan the possibility of the epidemiological diagnosis of fecal-oral hepatitis non A, non B, also known as hepatitis E, was confirmed. Analysis of the specific features of a sharp morbidity rise in hepatitis A in this region in 1986-1987 made it possible to establish that this rise was caused by hepatitis E. This was testified by the explosive character of morbidity; the prevalence of persons aged 15-29 years, found to have antibodies to hepatitis A virus in 95% of cases (among patients, these persons constituted 67.5% of the total number of hepatitis A patients and children of preschool age constituted only 8.8% of such patients); sharply pronounced irregularity in the distribution of morbidity in individual settlements, depending on the state of water supply; a low number of the foci of infection in patient's families; the unfavorable course of the disease in pregnant women with high mortality rate (19%) among them. Similar epidemiological features were noted in hepatitis E outbreaks, occurring at the same period in the adjoining regions in Kirghizia and Uzbekistan, where the etiology of the disease was established by excluding the markers of hepatitides A and B in most of the patients. Some data indicate that the causes of these outbreaks of hepatitis E were linked with the water route of the transmission of hepatitis E virus.
authors.forename: D M
authors.initials: DM
authors.lastname: Iarasheva
authors.forename: I V
authors.initials: IV
authors.lastname: Shakhgil'dian
authors.forename: Kh Ia
authors.initials: KhIa
authors.lastname: Aripov
authors.forename: V M
authors.initials: VM
authors.lastname: Psarev
authors.forename: M D
authors.initials: MD
authors.lastname: Kurbanov
authors.forename: U A
authors.initials: UA
authors.lastname: Akhmedov
authors.forename: R B
authors.initials: RB
authors.lastname: Dzhumaev
authors.forename: I M
authors.initials: IM
authors.lastname: Madaliev
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004196:Disease Outbreaks / Q000706:statistics & numerical data; D005243:Feces; D005260:Female; D006506:Hepatitis A / Q000175:diagnosis / Q000453:epidemiology; D016751:Hepatitis E / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D015994:Incidence; D012189:Retrospective Studies; D013620:Tajikistan / Q000453:epidemiology
vernacular_title: Epidemiologicheskaia diagnostika "fekal'no-oral'nogo" gepatita E v Tadzhikistane.