title: [The role of secondary immunodeficiencies in the development of a protracted course of acute dysentery].
abstract: An opinion on the expediency of working out criteria for dividing acute dysentery patients into risk groups, depending on the development of immune deficiency, has been put forward. The results of the study of some characteristics of T-cell immunity system in 228 acute dysentery patients in relation to their clinical state are presented. Measurements of total active T lymphocytes, T helpers and T suppressors have been made. Disturbances in the immunity characteristics under study, more pronounced in patients with a more severe and prolonged course of the disease, as well as in patients receiving belated treatment, have been noted. Besides the total number of T lymphocytes and their subpopulations, the imbalance of these cells is also an important feature. To solve the problem of prescribing immunocorrective therapy, not only immunological, but also clinical characteristics should be taken into consideration.
authors.forename: E M
authors.initials: EM
authors.lastname: Usychenko
authors.forename: V P
authors.initials: VP
authors.lastname: Mashilov
mesh_terms: D000208:Acute Disease; D000328:Adult; D004405:Dysentery, Bacillary / Q000150:complications* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000209:etiology* / Q000276:immunology; D007958:Leukocyte Count; D008875:Middle Aged; D012763:Shigella flexneri; D012764:Shigella sonnei; D016176:T-Lymphocyte Subsets / Q000276:immunology
vernacular_title: O roli vtorichnykh immunodefitsitov v formirovanii zatiazhnogo techeniia ostroĭ dizenterii.