Primitive neuroectodermal tumor of the retroperitoneal cavity.
We report a case of primitive neuroectodermal tumor (PNET) arising from the retroperitoneal cavity. Because of infiltration, the tumor was excised en bloc with the left kidney. Despite postoperative adjuvant chemotherapy and local radiation therapy, the tumor recurred and the patient died of the disease 3 months postoperatively. Serum levels of neuron-specific enolase (NSE) correlated with those of lactate dehydrogenase (LDH), and it is suggested that monitoring NSE and LDH is useful in evaluating tumor recurrence. The clinical course and the treatment of this aggressive tumor are reviewed.
Horiguchi
Y
Y
Department of Urology, Keio University School of Medicine, Tokyo, Japan.
Nakashima
J
J
Ishii
T
T
Hata
J
J
Tazaki
H
H
D000328:Adult; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000473:pathology*; D018242:Neuroectodermal Tumors, Primitive / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D010751:Phosphopyruvate Hydratase / Q000097:blood; D011379:Prognosis; D012186:Retroperitoneal Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed
D007770:L-Lactate Dehydrogenase; D010751:Phosphopyruvate Hydratase