title: Use of scalp-sphenoidal EEG for seizure localization in temporal lobe epilepsy.
abstract: We determined the accuracy and sensitivity of scalp-sphenoidal EEG for seizure focus localization in 50 patients who became seizure-free or had rare seizures following temporal lobectomy. EEG localization was based on concordant interpretations of scalp-sphenoidal ictal EEG by three independent interpreters. All patients became seizure-free or had rare seizures following temporal lobectomy. Localization from EEG disagreed with the side of surgery in only 1 (2%) of 50 patients. We identified 3 distinct patient groups with a low, moderate, and high likelihood of having a focal ictal EEG pattern during a seizure. These groups comprised 31% (low likelihood), 44% (moderate likelihood), and 25% (high likelihood) of patients. A model based on these results suggests that with multiple ictal EEG recordings, accurate localization from scalp-sphenoidal EEG is possible in approximately up to 65-70% of patients with temporal lobe epilepsy.
authors.affiliation: Department of Neurology, VA Medical Center, Augusta, GA 30912.
authors.forename: A M
authors.initials: AM
authors.lastname: Murro
authors.forename: Y D
authors.initials: YD
authors.lastname: Park
authors.forename: D W
authors.initials: DW
authors.lastname: King
authors.forename: B B
authors.initials: BB
authors.lastname: Gallagher
authors.forename: J R
authors.initials: JR
authors.lastname: Smith
authors.forename: W
authors.initials: W
authors.lastname: Littleton
mesh_terms: D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D015588:Observer Variation