[Recording of surface potential changes in erythrocyte membranes from patients with insulin-dependent diabetes mellitus using a spin probe method].
Changes in surface potential of erythrocyte membranes were studied by a positively charged analog as a spin probe. Insulin-dependent diabetes mellitus (IDDM) patients demonstrated a significant increase (by 16 +/- 2.0 mV) in negative surface potential as compared to the control. An important role of this phenomenon in pathogenesis of IDDM is discussed.
Maksina
A G
AG
Mikaélian
N P
NP
Daĭniak
B A
BA
Kniazev
Iu A
IuA
D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D004578:Electron Spin Resonance Spectroscopy; D004910:Erythrocyte Membrane / Q000502:physiology*; D006801:Humans; D008564:Membrane Potentials; D013113:Spin Labels
D013113:Spin Labels
Registratsiia metodom spinovogo zonda izmeneniĭ poverkhnostnogo potentsiala membran éritrotsitov krovi bol'nykh insulinzavisimym sakharnym diabetom.