[Serum factors in rabbits with acute pancreatitis as stimulators of regeneration of pancreatic islet B-cells in experimental diabetes].
The experiment reveals the stimulating effect of pancreatic rabbits' serum on the reparative regeneration of pancreatic islets' B-cells of rabbits with alloxan diabetes. Serum, got 12 hours after mechanical pancreatic gland trauma proves to be most effective. The maximum rise of mitotic activity is in 24 hours after 3 daily injections of serum. In the experiment with the decrease of the level of proliferation of B-cells compensation of insulinary function by acinoinsulary transformation prevails.
Zharkov
V P
VP
Iarygin
V N
VN
Dolzhikov
A A
AA
D000208:Acute Disease; D000818:Animals; D001685:Biological Factors / Q000097:blood / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D003921:Diabetes Mellitus, Experimental / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D005260:Female; D007515:Islets of Langerhans / Q000503:physiopathology*; D008297:Male; D010195:Pancreatitis / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D011817:Rabbits; D012038:Regeneration / Q000502:physiology*
D001685:Biological Factors
Syvorotochnye faktory krolikov s ostrym pankreatitom kak stimuliatory regeneratsii B-kletok pankreaticheskikh ostrovkov pri éksperimental'nom diabete.