Mantle-cell lymphomas of the skin.
The skin lesions of two elderly women lead us to the diagnosis of small cleaved lymphocytic B-cell non-Hodgkin's lymphoma, TNM stage IVb after clinical staging examinations. Relapses occurred within less than 1 year. Morphology, enzymhistochemistry (alkaline phosphatase in the first case), and immunohistochemistry (CD 5 positivity in the second case) in the skin biopsies supported the diagnosis of mantle-cell lymphoma. The histogenesis of the mantle-cell lymphoma is reviewed.
Geerts
M L
ML
Department of Dermatology, University Hospital Ghent, Belgium.
Busschots
A M
AM
D000368:Aged; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000628:therapy; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology* / Q000628:therapy