Clinical trial of pentazocine as analgesic in paediatric cases.
This study was undertaken with the objective of relieving pain which has been poorly understood and managed in peri-operative period specially in children. Here the analgesic efficacy of pentazocine was studied in 50 cases, aged between 5 and 9 years subjected to both major and minor surgeries. No premedication was given to assess the sole analgesic effect of the drug. Pentazocine was given during induction, dose being 0.5 mg/kg body weight intravenously. Subsequently small incremental doses were repeated after every 30-45 minutes during surgery. Satisfactory analgesia was obtained during intra- and postoperative period. No respiratory depression, no change in pulse, BP and no other complications were observed after administration of intravenous pentazocine.
Ray
A D
AD
Department of Anaesthesiology, Calcutta Medical College and Hospitals.
Gupta
M
M
D000698:Analgesia; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007275:Injections, Intravenous; D007430:Intraoperative Care; D010149:Postoperative Pain / Q000517:prevention & control*; D010423:Pentazocine
D010423:Pentazocine