title: Doppler echocardiographic evaluation of left ventricular output and left ventricular diastolic filling changes in the first day of life.
abstract: The aim of this study was to evaluate the changes in Doppler transmitral flow patterns during the 1st d of life. Doppler echocardiography of the ascending aorta and mitral valve was performed serially in 20 normal neonates at 2, 12, and 24 h of age. A computer-interfaced digitizer pad was used to measure the following: ascending aorta flow velocity-time integral, total diastolic filling flow velocity-time integral, flow velocity-time integral of early diastolic filling, and flow velocity-time integral of atrial contraction. The inner diameter of the ductus arteriosus was 4.2 +/- 0.6 mm at 2 h of age, 2.3 +/- 0.5 mm at 12 h of age, and had closed in 17 of 20 neonates (85%) by 24 h of age. The ascending aorta flow velocity-time integral and total diastolic filling flow velocity-time integral, which were high at 2 h of age, decreased significantly at 12 h of age [12.2 +/- 2.1 cm versus 9.6 +/- 1.7 cm (p < 0.001) and 8.0 +/- 1.1 versus 7.1 +/- 1.4 (p < 0.01), respectively] but remained constant thereafter.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Pediatrics, Akita University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Harada
authors.forename: T
authors.initials: T
authors.lastname: Shiota
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Toyono
authors.forename: G
authors.initials: G
authors.lastname: Takada
mesh_terms: D002302:Cardiac Output; D003971:Diastole; D015150:Echocardiography, Doppler; D006339:Heart Rate; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D008943:Mitral Valve; D015588:Observer Variation; D012016:Reference Values; D014584:User-Computer Interface; D016277:Ventricular Function, Left