Functional imaging and language: evidence from positron emission tomography.
Positron emission tomography (PET) provides an unprecedented opportunity to study the organization of cognitive functions in the working brain of normal individuals. A number of PET experiments, based on well-established paradigms derived from cognitive psychology, have investigated several aspects of language processing. These studies show that word processing is carried out by a distributed network of cortical areas with functional specificity. Results of this research sometimes confirm--sometimes clearly contradict--classic axioms of language organization. This article illustrates some of the methodological issues in PET research, then provides an overview of the most relevant studies using PET. Integrated with other functional imaging methodologies and with behavioral data from cognitive psychology and lesion studies, PET will certainly continue to represent a precious tool to enhance our knowledge of the functional organization of language.
Liotti
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Research Imaging Center, University of Texas Health Science Center at San Antonio 78284-6240.
Gay
C T
CT
Fox
P T
PT
D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism; D002560:Cerebrovascular Circulation; D006801:Humans; D007802:Language; D008606:Mental Processes / Q000502:physiology; D010700:Phonetics; D010775:Photic Stimulation; D012660:Semantics; D013060:Speech / Q000502:physiology*; D014055:Tomography, Emission-Computed; D014796:Visual Perception