Cloning and sequence analysis of blaBIL-1, a plasmid-mediated class C beta-lactamase gene in Escherichia coli BS.
The extended-spectrum, plasmid-borne beta-lactamase gene blaBIL-1, which was discovered in Escherichia coli, has been cloned. Unusually for a plasmid-borne beta-lactamase, blaBIL-1 encodes a novel class C enzyme and appears to have originated from the chromosomal ampC gene of Citrobacter freundii.
Fosberry
A P
AP
SmithKline Beecham Pharmaceuticals, Brockham Park, Betchworth, Surrey, United Kingdom.
Payne
D J
DJ
Lawlor
E J
EJ
Hodgson
J E
JE
D000595:Amino Acid Sequence; D001483:Base Sequence; D016971:Citrobacter freundii / Q000187:drug effects / Q000235:genetics; D003001:Cloning, Molecular; D016172:DNA Fingerprinting; D017931:DNA Primers; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005798:Genes, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics*; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics*
D017931:DNA Primers; D001618:beta-Lactamases