[Neuroradiological findings in perinatally HIV-infected children].
The neuroradiological studies (CT, MRI, angiography) in 21 children with perinatal HIV infection were reviewed retrospectively. No patient showed an intracranial mass lesion; after intravenous contrast medium application there was no case with disturbed blood-brain barrier. Common non-specific findings were atrophy and delayed myelination. In 7 cases atrophy was combined with multifocal nearly symmetric white matter lesions, which characteristically spared the U-fibres. Further findings included an intramedullary ring-shaped structure in the cervical cord, an AIDS-associated vasculopathy and symmetric calcifications in the basal ganglia. The spectrum of neuroradiological findings in paediatric AIDS patients differs from that in adults. Knowledge of these age-specific findings is important because the number of HIV-infected children is rising.
Spreer
J
J
Radiologische Abteilung, Universitätsklinik Köln.
Enenkel-Stoodt
S
S
Funk
M
M
Fiedler
A
A
de Simone
A
A
Hacker
H
H
D000367:Age Factors; D001284:Atrophy; D001479:Basal Ganglia / Q000473:pathology; D001921:Brain / Q000473:pathology; D002490:Central Nervous System / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies; D013116:Spinal Cord / Q000473:pathology; D014057:Tomography, X-Ray Computed
Neuroradiologische Befunde bei perinatal HIV-infizierten Kindern.