[Current strategy and tactics of etiotropic therapy of acute intestinal infections in children].
Efficacy of various types of etiotropic therapy in 1646 children with acute intestinal infections (AIIs) treated in the Infectious Department in 1977-1989 was analyzed by comparison with the data on drug resistance of the pathogens. It was shown advisable to apply etiotropic therapy only to patients with AIIs of invasive genesis with a differential approach to the drug choice and an account of the disease severity and phase, patient age, properties of the drugs and pathogens. Follow-up of the pathogen drug resistance by quarterly reports on antibiotic resistance of the circulating pathogens was found expedient. Efficacy of the reserve drugs in treatment of severe and general AIIs and advantages of phage monotherapy and phage combined therapy in patients with AIIs of the moderate and low severity by comparison with the use of antibiotics and chemotherapeutics were also shown. The first experience with the use of original complex immunoglobulin for enteral administration in therapy of AIIs proved promising.
Miliutina
L N
LN
Vorotyntseva
N V
NV
D000208:Acute Disease; D001424:Bacterial Infections / Q000628:therapy*; D002648:Child; D004352:Drug Resistance, Microbial; D005500:Follow-Up Studies; D006801:Humans; D007410:Intestinal Diseases / Q000628:therapy*; D012189:Retrospective Studies
Strategii i taktika étiotropnoĭ terapii ostrykh kishechnykh infektsiĭ u deteĭ na sovremennom étape.