Deterioration of mixed cryoglobulinemia during treatment with interferon-alpha-2a.
A 60-year-old female developed mixed cryoglobulinemia associated with liver cirrhosis caused by the hepatitis C virus. During treatment with rIFN-alpha-2a, deterioration of cryoglobulinemia was recognized. The possible mechanisms underlying the deterioration are discussed.
Bojić
I
I
Clinic of Infectious and Tropical Diseases, Military Medical Academy, Belgrade, Yugoslavia.
Lilić
D
D
Radojcić
C
C
Mijusković
P
P
D000368:Aged; D000936:Antigen-Antibody Complex / Q000276:immunology; D003449:Cryoglobulinemia / Q000150:complications / Q000276:immunology / Q000628:therapy*; D003450:Cryoglobulins / Q000032:analysis; D005260:Female; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000009:adverse effects / Q000627:therapeutic use*; D008103:Liver Cirrhosis / Q000150:complications; D011994:Recombinant Proteins
D000936:Antigen-Antibody Complex; D003450:Cryoglobulins; D007136:Immunoglobulins; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins