title: Crystallization and preliminary X-ray analysis of a trimeric form of human mannose binding protein.
abstract: A trimeric form of the carbohydrate recognition domain of human mannose binding protein has been crystallized in two different forms. The first form crystallizes with symmetry consistent with space group P2(1)2(1)2(1) and a = 61 A; b = 144 A; c = 107 A with presumably two trimers in the asymmetric unit. The second form crystallizes with symmetry consistent with space group P321 and a = b = 77 A; c = 58 A and one monomer per asymmetric unit. The molecular and crystallographic 3-folds must be coincident in this crystal form.
authors.affiliation: Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543-4000.
authors.forename: C Y
authors.initials: CY
authors.lastname: Chang
authors.forename: K N
authors.initials: KN
authors.lastname: Sastry
authors.forename: S D
authors.initials: SD
authors.lastname: Gillies
authors.forename: R A
authors.initials: RA
authors.lastname: Ezekowitz
authors.forename: S
authors.initials: S
authors.lastname: Sheriff
mesh_terms: D002352:Carrier Proteins / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D006801:Humans; D037241:Mannose-Binding Lectins; D015394:Molecular Structure; D008970:Molecular Weight; D011487:Protein Conformation
chemical_list: D002352:Carrier Proteins; D037241:Mannose-Binding Lectins