title: Malignant fibrous histiocytoma at the site of hip replacement in association with chronic infection.
abstract: A case of malignant fibrous histiocytoma that developed at the site of an infected metallic implant is presented. The total hip endoprosthesis was composed of a cobalt-chromium alloy. There was a relatively short latency period (less than 2 years) between the initial surgery and the development of malignancy in this patient. The authors urge development of a tumor registry to discover if the association between hip replacement and malignancy is coincidental.
authors.affiliation: George Washington University Department of Orthopaedic Surgery.
authors.forename: A J
authors.initials: AJ
authors.lastname: Aboulafia
authors.forename: K
authors.initials: K
authors.lastname: Littelton
authors.forename: B
authors.initials: B
authors.lastname: Shmookler
authors.forename: M M
authors.initials: MM
authors.lastname: Malawer
mesh_terms: D000497:Alloys / Q000009:adverse effects; D002857:Chromium; D002908:Chronic Disease; D003035:Cobalt; D003343:Corrosion; D005260:Female; D006621:Hip Joint; D006622:Hip Prosthesis / Q000009:adverse effects*; D018219:Histiocytoma, Benign Fibrous / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D017169:Neoplasms, Post-Traumatic / Q000209:etiology*; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000150:complications*; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000497:Alloys; D002857:Chromium; D003035:Cobalt