title: Serum iron, total iron binding capacity and ferritin in early Huntington disease patients.
abstract: Serum iron, total iron binding capacity and ferritin was estimated in 42 patients with early Huntington disease (HD) and in 148 matched controls. Ferritin levels were significantly low in affected male subjects as compared to controls. Iron levels and total iron binding capacity were normal in HD patients. The importance of this finding, that occurs early in the pathogenesis of HD, is unknown.
authors.affiliation: Department of Medical Genetics, Queen's University of Belfast, Belfast City Hospital.
authors.forename: P J
authors.initials: PJ
authors.lastname: Morrison
authors.forename: N C
authors.initials: NC
authors.lastname: Nevin
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D006816:Huntington Disease / Q000097:blood* / Q000378:metabolism; D007501:Iron / Q000097:blood* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011485:Protein Binding; D013997:Time Factors
chemical_list: D005293:Ferritins; D007501:Iron