title: Asthma severity and morbidity in a population sample of Sydney school children: Part I--Prevalence and effect of air pollutants in coastal regions.
abstract: BACKGROUND
  In two regions of Sydney where sewage treatment facilities with high temperature sludge burning incinerators are installed, there was concern that the resultant emissions were causing a local increase in symptoms of asthma and other allergic diseases.
  
  
  OBJECTIVE
  To investigate whether living in a region with high temperature sludge burning incinerators was associated with an increased prevalence of childhood asthma or allergy.
  
  
  METHODS
  We studied 713 children aged eight-12 years in two regions close to incinerators and 626 children in a control region with no sludge burning incinerator. We measured respiratory illness in the previous year by questionnaire, airway hyper-responsiveness (AHR) by histamine inhalation test, and atopy by skin prick tests. 'Current asthma' was defined as AHR and recent wheeze.
  
  
  RESULTS
  Recordings of oxides of nitrogen and sulphur, hydrogen sulphide, ozone and particulates during the study period showed that the level of pollutants did not vary in any major way between the study regions and the control region. The prevalence of current asthma, atopy, symptom frequency or any category of severity of asthma illness was not significantly different between the control and study regions.
  
  
  CONCLUSIONS
  This suggests that factors other than intermittent or industrial air pollutants are responsible for the high prevalence of asthma symptoms, asthma medication use, asthma morbidity and AHR in the study of children.
authors.affiliation: Department of Medicine, University of Sydney, NSW.
authors.forename: E J
authors.initials: EJ
authors.lastname: Gray
authors.forename: J K
authors.initials: JK
authors.lastname: Peat
authors.forename: C M
authors.initials: CM
authors.lastname: Mellis
authors.forename: J
authors.initials: J
authors.lastname: Harrington
authors.forename: A J
authors.initials: AJ
authors.lastname: Woolcock
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects*; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology*; D001315:Australia / Q000453:epidemiology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008685:Meteorological Concepts; D009017:Morbidity; D015995:Prevalence; D012129:Respiratory Function Tests; D012720:Severity of Illness Index; D012882:Skin Tests; D011795:Surveys and Questionnaires; D014505:Urban Population
chemical_list: D000393:Air Pollutants