title: Disseminated cutaneous and meningeal sporotrichosis in an AIDS patient.
abstract: We report the first proven case of Sporothrix meningoencephalitis in an AIDS patient. The patient had dramatic, wide-spread ulcerative and infiltrative disease with progressive meningoencephalitis in spite of amphotericin and itraconazole therapy. Sporothrix was cultured from premortem cerebrospinal fluid and seen in the meninges and in brain vessels at autopsy.
authors.affiliation: Department of Medicine, Medical College of Ohio, Toledo 43699.
authors.forename: H
authors.initials: H
authors.lastname: Donabedian
authors.forename: E
authors.initials: E
authors.lastname: O'Donnell
authors.forename: C
authors.initials: C
authors.lastname: Olszewski
authors.forename: R D
authors.initials: RD
authors.lastname: MacArthur
authors.forename: N
authors.initials: N
authors.lastname: Budd
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000473:pathology*; D000328:Adult; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D013175:Sporothrix; D013174:Sporotrichosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D015725:Fluconazole