[The effect of cytostatics on the course and outcomes of experimental herpes infection in rabbits].
As a result of herpes simplex virus reactivation with holoxan in rabbit reconvalescents with acute primary herpetic keratoconjunctivitis, the ophthalmic herpes relapse was observed and it was characterized by a more severe and prolonged course with longterm viremia and generalization of the infection. In the survived animals the chronic, recurrent ophthalmic herpes was developed.
Kolomiets
A G
AG
Gasich
E L
EL
Duboĭskaia
G P
GP
Chekina
A Iu
AIu
Moroz
A G
AG
Barinskiĭ
I F
IF
Votiakov
V I
VI
D000208:Acute Disease; D000818:Animals; D005260:Female; D006564:Herpesviridae / Q000254:growth & development; D007069:Ifosfamide / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D016849:Keratitis, Herpetic / Q000382:microbiology / Q000473:pathology*; D008297:Male; D011817:Rabbits; D012008:Recurrence; D016896:Treatment Outcome; D014766:Viremia; D014775:Virus Activation
D007166:Immunosuppressive Agents; D007069:Ifosfamide
Vliianie tsitostatika na techenie i iskhody éksperimental'noĭ gerpeticheskoĭ infektsii u krolikov.