title: Ocular fibropapillomas of green turtles (Chelonia mydas).
abstract: Histologic evaluation of four eyes from three stranded juvenile green turtles (Chelonia mydas) from Florida, USA revealed ocular fibropapillomas composed of an overlying hyperplastic epithelium, various amounts of a thickened, well vascularized, collagenous stroma, and a moderate-to-dense population of reactive fibroblasts. The histologic morphology of the ocular fibropapillomas varied depending on whether the eyelid, conjunctiva, limbus, or cornea was the primary site of tumor origin. Fibropapillomas arising from the limbus, conjunctiva, or eyelid tended to be polyploid or pedunculated with a high degree of arborization. They often filled the conjunctival fornices and extended externally to be ulcerated on the distal aspects. Corneal fibropapillomas were more sessile and multinodular with less arborization. Some corneal tumors consisted primarily of a broad fibrovascular stroma and mild epithelial hyperplasia, whereas others had a markedly hyperplastic epithelium supported by stalks of fibrovascular stromal tissue. In green turtles ocular fibropapillomas may be locally invasive and associated with severe blindness and systemic debilitation.
authors.affiliation: Department of Large and Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville.
authors.forename: D E
authors.initials: DE
authors.lastname: Brooks
authors.forename: P E
authors.initials: PE
authors.lastname: Ginn
authors.forename: T R
authors.initials: TR
authors.lastname: Miller
authors.forename: L
authors.initials: L
authors.lastname: Bramson
authors.forename: E R
authors.initials: ER
authors.lastname: Jacobson
mesh_terms: D000818:Animals; D003228:Conjunctiva / Q000473:pathology; D003315:Cornea / Q000473:pathology; D005134:Eye Neoplasms / Q000473:pathology / Q000662:veterinary*; D005143:Eyelids / Q000473:pathology; D010212:Papilloma / Q000473:pathology / Q000662:veterinary*; D011127:Polyps / Q000473:pathology / Q000662:veterinary*; D014426:Turtles