title: Staging and surveillance of children with central nervous system neoplasms: recommendations of the Neurology and Tumor Imaging Committees of the Children's Cancer Group.
abstract: Standardization of the baseline and surveillance evaluation of children with central nervous system (CNS) tumors could contribute to understanding tumor behavior, establishing prognoses, directing treatment, and interpreting multi-institutional cooperative study data. A tumor categorization schedule, based on recognized patterns of CNS tumor behavior involving 'aggressiveness' as assessed by the likelihood for neuraxis dissemination, relative time to progression and pattern of disease recurrence is presented. Included are the most common histologic subtypes of pediatric CNS neoplasms. No attempt has been made to include all histologic subtypes of pediatric CNS neoplasms. Using this categorization as a framework, recommendations are suggested for baseline evaluation at diagnosis and in surveillance.
authors.affiliation: Neuro-Oncology Program, Cooper Hospital/University Medical Center, UMDNJ/Robert Wood Johnson Medical School, Camden.
authors.forename: E D
authors.initials: ED
authors.lastname: Kramer
authors.forename: L G
authors.initials: LG
authors.lastname: Vezina
authors.forename: R J
authors.initials: RJ
authors.lastname: Packer
authors.forename: C R
authors.initials: CR
authors.lastname: Fitz
authors.forename: R A
authors.initials: RA
authors.lastname: Zimmerman
authors.forename: M D
authors.initials: MD
authors.lastname: Cohen
mesh_terms: D000293:Adolescent; D014408:Biomarkers, Tumor; D001932:Brain Neoplasms / Q000175:diagnosis*; D002555:Cerebrospinal Fluid / Q000166:cytology; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D011159:Population Surveillance; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor