title: [Influence of ionized calcium concentration during cardiopulmonary bypass on pediatric cardiac surgery].
abstract: Changes of serum ionized calcium concentration (Ca2+) during cardiopulmonary bypass (CPB) were analyzed in 30 pediatric cardiac patients less than 15 kg body weight. Ca2+ decreased suddenly after the start of CPB, and it gradually increased to the normal value. Citrate added to the stored blood for priming and its metabolism might play a role in these changes of Ca2+. Addition of adequate volume of calcium chloride to the priming prevented sudden decrease of Ca2+. Although addition of citrate before aortic declamp effectively decreased Ca2+ and may prevent reperfusion cardiac injury associated with hypercalcemia, there were no correlation between predeclamp level of Ca2+ and serum CPK and GOT levels.
authors.affiliation: Department of Surgery, University of Tsukuba, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Atsumi
authors.forename: M
authors.initials: M
authors.lastname: Abe
authors.forename: Y
authors.initials: Y
authors.lastname: Sakakibara
authors.forename: Y
authors.initials: Y
authors.lastname: Terada
authors.forename: T
authors.initials: T
authors.lastname: Jikuya
authors.forename: T
authors.initials: T
authors.lastname: Tsutsui
authors.forename: K
authors.initials: K
authors.lastname: Okamura
authors.forename: T
authors.initials: T
authors.lastname: Mitsui
authors.forename: M
authors.initials: M
authors.lastname: Hori
mesh_terms: D001835:Body Weight; D002118:Calcium / Q000097:blood*; D002122:Calcium Chloride / Q000008:administration & dosage; D002315:Cardiopulmonary Bypass; D002951:Citrates / Q000008:administration & dosage / Q000097:blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control
chemical_list: D002951:Citrates; D002122:Calcium Chloride; D002118:Calcium