Blood pressure responses to dynamic exercise with lower-body positive pressure.
Cardiovascular responses were obtained during cycling with graded levels of lower-body positive pressure (LBPP) applied to the exercising limbs. Seven men performed four incremental work rate (25 W.min-1) exercise (IWREx) tests to their limit of tolerance while exposed to 0, 15, 30, or 45 Torr LBPP. They also performed four, 6-min constant work rate exercise (CWREx) bouts at two work rates with LBPP's of 0 and 45 Torr. Cardiovascular data were obtained at rest and at 40%, 55%, 75%, and 90% of VO2peak, as well as at minute 5 of CWREx. LBPP did not alter VO2, HR, SV, or cardiac output (Qc) responses at rest or during exercise. However, both 30 and 45 Torr LBPP produced increases in MAP at rest and during exercise (P < 0.05). During CWREx, elevations in blood pressure were mediated via increases in TPR (P < 0.05). Only 45 Torr LBPP elicited a significantly greater blood pressure increase during exercise than rest, suggesting muscle blood flow restriction at this level of LBPP was sufficient to activate a muscle metabo-reflex. These findings suggest that the muscle metabo-reflex is not tonically active during dynamic exercise under normal conditions, but may instead require a critical reduction in muscle blood flow before it is activated.
Williamson
J W
JW
Department of Physiology, Texas College of Osteopathic Medicine, Fort Worth 76107.
Crandall
C G
CG
Potts
J T
JT
Raven
P B
PB
D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D002302:Cardiac Output / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008465:Mechanoreceptors / Q000502:physiology; D009132:Muscles / Q000098:blood supply / Q000502:physiology; D010101:Oxygen Consumption / Q000502:physiology; D005082:Physical Exertion; D011312:Pressure; D012018:Reflex / Q000502:physiology; D013318:Stroke Volume / Q000502:physiology