Primary nodular cutaneous amyloidosis--long-term follow-up and treatment.
A case of facial primary nodular cutaneous amyloidosis is reported. This illustrates: the striking appearance of this unusual condition; the investigations appropriate to establish the diagnosis and to exclude underlying systemic amyloidosis or a condition which might contribute to amyloidosis; and the difficulty of successful management. Initial investigation failed to reveal any evidence of systemic amyloidosis or an associated internal illness. Two amyloid nodules were excised, but 7 years later the patient developed further nodules on the adjacent facial skin and again sought dermatological advice. He was reinvestigated and again no underlying condition was found. A trial of cryotherapy was unsuccessful, but curettage and cautery produced a cosmetically acceptable result.
Vestey
J P
JP
University Department of Dermatology, Royal Infirmary of Edinburgh, UK.
Tidman
M J
MJ
Mclaren
K M
KM
D000328:Adult; D000686:Amyloidosis / Q000473:pathology / Q000628:therapy*; D005148:Facial Dermatoses / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D009666:Nose