title: Single X-ray absorptiometry of the forearm: precision, correlation, and reference data.
abstract: The performance of a single X-ray absorptiometry (SXA) device incorporating an X-ray tube as a photon source was evaluated with respect to precision in vivo and in vitro, scan time, image quality, and correlation with an existing dual energy X-ray absorptiometry (DXA) device. SXA precision in vivo, expressed as a coefficient of variation (CV), was 0.66% for bone mineral content (BMC) and 1.05% for bone mineral density (BMD). Precision in vitro, based on 78 BMC measurements of a forearm phantom over 195 days, was 0.53%. Correlation with DXA at the 8 mm distal forearm site was high (r = 0.97 for BMC and r = 0.96 for BMD). A preliminary SXA reference database composed of 151 healthy Caucasian American women was developed to facilitate the interpretation of patient measurements. SXA scan time was 4 minutes and delivered a radiation exposure of 1.68 mrem. SXA image quality and spatial resolution were superior to SPA and comparable to DXA.
authors.affiliation: Hologic, Inc., Waltham, Massachusetts 02154.
authors.forename: T L
authors.initials: TL
authors.lastname: Kelly
authors.forename: G
authors.initials: G
authors.lastname: Crane
authors.forename: D T
authors.initials: DT
authors.lastname: Baran
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D003198:Computer Simulation; D005260:Female; D005542:Forearm; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000503:physiopathology; D012016:Reference Values; D015203:Reproducibility of Results