title: Studies of any toxicological effects of Prussian blue compounds in mammals--a review.
abstract: The Chernobyl nuclear reactor accident, which resulted in widespread contamination with radiocaesium, led to studies of the use of Prussian Blue (PB) compounds as a countermeasure to reduce the caesium-137 and caesium-134 content of animal products. An important consideration in the practical use of PB compounds in agriculture is their possible toxicity. Hence it is pertinent to assess the work undertaken with laboratory rodents, domesticated animals and humans that has included studies of any toxic effects. Such studies showed that PB compounds had no adverse effects on animal health and production and, in addition, no toxic effects were noted in humans when PB was used experimentally or therapeutically.
authors.affiliation: Department of Food and Agricultural Chemistry, Queen's University of Belfast.
authors.forename: J
authors.initials: J
authors.lastname: Pearce
mesh_terms: D000818:Animals; D002588:Cesium Radioisotopes / Q000493:pharmacokinetics / Q000506:poisoning; D005260:Female; D005295:Ferrocyanides / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use / Q000633:toxicity*; D006801:Humans; D008297:Male; D008322:Mammals; D012098:Reproduction / Q000187:drug effects; D013793:Thallium / Q000506:poisoning
chemical_list: D002588:Cesium Radioisotopes; D005295:Ferrocyanides; D013793:Thallium; C000170:ferric ferrocyanide