Intracranial tuberculoma and hydrocephalus developing during treatment of tuberculous meningitis.
A 3 1/2-year-old boy with tuberculous meningitis is described. He developed hydrocephalus and subsequently an intracranial tuberculoma while receiving appropriate antituberculous therapy. Such a paradoxical response is thought to be due to a hypersensitivity reaction to the infection during antituberculous therapy. Both hydrocephalus and tuberculomata should be looked for if any patient develops new neurological signs or symptoms during treatment of tuberculous meningitis.
Wong
G W
GW
Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT.
Oppenheimer
S J
SJ
Poon
W
W
Leung
R
R
D000995:Antitubercular Agents / Q000009:adverse effects*; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D006849:Hydrocephalus / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D008297:Male; D014057:Tomography, X-Ray Computed; D016862:Tuberculoma, Intracranial / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D014390:Tuberculosis, Meningeal / Q000188:drug therapy*; D017287:Ventriculoperitoneal Shunt
D000995:Antitubercular Agents; D003907:Dexamethasone