title: [Multiple sclerosis: acute state or malignant course?].
abstract: Multiple sclerosis (MS) which had developed in a 19-year-old female patient took a malignant course and terminated fatally three years after first symptoms. The case was characterized by an acute onset, seven severe exacerbations against combined pyramidal, cerebellar, visual, psychopathological and hyperkinetic disorders. The authors believe improper application of the term "acute" to rapid lethal outcome cases. In their opinion, they should be called cases of MS malignant course, the latter implying an unfavourable outcome of MS due to primarily truncal location of the demyelination process.
authors.forename: A A
authors.initials: AA
authors.lastname: Shutov
authors.forename: T V
authors.initials: TV
authors.lastname: Baĭdina
authors.forename: N V
authors.initials: NV
authors.lastname: Zotova
mesh_terms: D000208:Acute Disease; D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000473:pathology* / Q000628:therapy; D009626:Terminology as Topic
vernacular_title: Rasseiannyĭ skleroz: ostrye formy ili zlokachestvennoe techenie?.