[Cytokines and malaria. A study of TNF-alpha, IL1-beta, IL6 and IL2R in 28 patients].
Authors have studied TNF alpha, IL1 bêta, IL6 and RIL2s in 28 malaria illness patients. Increased levels of TNF, IL1 bêta and RIL2s in serum, are observed on admission to hospital. These cytokine levels are decreased, eight days later, after patients are treated. In discussion, TNF levels as a prognosis component is evocated.
Nicolas
P
P
Laboratoire de Biologie Clinique de l'Hôpital d'Instruction des Armées Laveran, Marseille.
Hovette
P
P
Merouze
F
F
Touze
J E
JE
Martet
G
G
D000293:Adolescent; D000328:Adult; D000655:Amodiaquine / Q000627:therapeutic use; D002097:C-Reactive Protein / Q000032:analysis; D002738:Chloroquine / Q000627:therapeutic use; D006801:Humans; D007375:Interleukin-1 / Q000032:analysis*; D015850:Interleukin-6 / Q000032:analysis*; D007958:Leukocyte Count; D008288:Malaria / Q000188:drug therapy / Q000276:immunology*; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000276:immunology; D016780:Malaria, Vivax / Q000188:drug therapy / Q000276:immunology; D015767:Mefloquine / Q000627:therapeutic use; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology; D010976:Platelet Count; D011379:Prognosis; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D012189:Retrospective Studies; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
D007375:Interleukin-1; D015850:Interleukin-6; D015375:Receptors, Interleukin-2; D014409:Tumor Necrosis Factor-alpha; D000655:Amodiaquine; D002738:Chloroquine; D002097:C-Reactive Protein; D015767:Mefloquine
Cytokines et paludisme. Etude du TNF alpha, de l'IL1 bêta, de l'IL6 et du RIL2s chez 28 malades.