[Detection of an unusual varicella zoster virus infection in an immunosuppressed patient with polymerase chain reaction].
We report a case of a 76-year-old patient who developed an atypical form of varicella zoster virus (VZV) reinfection. In addition to histological and serological confirmation of diagnosis, direct demonstration of VZV-DNA was possible by means of the nested polymerase chain reaction. Although VZV infection is usually diagnosed by clinical examination, the nested PCR is a sensitive and specific diagnostic procedure that can be useful especially in atypical cases.
Schaller
J
J
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitäts-Klinikums Essen.
Rohwedder
A
A
Breier
B
B
Werchau
H
H
D000212:Acyclovir / Q000627:therapeutic use; D000368:Aged; D001379:Azathioprine / Q000008:administration & dosage* / Q000009:adverse effects; D002644:Chickenpox / Q000188:drug therapy / Q000276:immunology*; D003588:Cytopathogenic Effect, Viral; D005260:Female; D014645:Herpesvirus 3, Human / Q000302:isolation & purification*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy* / Q000276:immunology; D009894:Opportunistic Infections / Q000188:drug therapy / Q000276:immunology*; D010392:Pemphigus / Q000188:drug therapy* / Q000276:immunology; D016133:Polymerase Chain Reaction; D011241:Prednisone / Q000008:administration & dosage* / Q000009:adverse effects
D001379:Azathioprine; D011241:Prednisone; D000212:Acyclovir
Nachweis einer ungewöhnlichen Varizella-Zoster-Virusinfektion unter Immunsuppression mit der Polymerase-Kettenreaktion.