title: Comparison of stimulated parotid salivary gland flow rates in normotensive and hypertensive persons.
abstract: Although hypertension is a prevalent condition among the elderly, little is known with respect to the influence of hypertension on oral health and function. Therefore a study was conducted that compared stimulated parotid salivary flow rates in elderly persons (65 years and older) from two diverse populations who are normotensive, mild, and severe hypertensive. The normotensive group consisted of 45 healthy subjects with systolic blood pressures of less than 140 mm Hg and diastolic pressures less than 90 mm Hg. The mildly hypertensive group consisted of 14 otherwise healthy subjects with either systolic pressures greater than 140 mm Hg or diastolic pressures greater than 90 mm Hg. The severely hypertensive group consisted of 10 otherwise healthy subjects with either systolic pressures greater than 180 mm Hg and/or diastolic pressures greater than 100 mm Hg. All three groups were not taking any prescription or nonprescription medications. Samples of 2% citrate-stimulated parotid saliva were collected from each subject. The results showed no significant differences in stimulated parotid flow between normotensive, mildly hypertensive, and severely hypertensive subjects. These results suggest that hypertension per se has no influence on stimulated parotid salivary gland flow rates in otherwise healthy, elderly unmedicated white and African-American persons.
authors.affiliation: National Institutes of Health, Bethesda, Md.
authors.forename: C F
authors.initials: CF
authors.lastname: Streckfus
authors.forename: A J
authors.initials: AJ
authors.lastname: Wu
authors.forename: J A
authors.initials: JA
authors.lastname: Ship
authors.forename: L J
authors.initials: LJ
authors.lastname: Brown
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D000704:Analysis of Variance; D015142:Baltimore; D044383:Black People; D001794:Blood Pressure; D002951:Citrates / Q000494:pharmacology; D019343:Citric Acid; D005260:Female; D006801:Humans; D006973:Hypertension / Q000208:ethnology / Q000503:physiopathology*; D008297:Male; D010306:Parotid Gland / Q000502:physiology / Q000503:physiopathology*; D012463:Saliva / Q000378:metabolism*; D012636:Secretory Rate; D013268:Stimulation, Chemical; D044465:White People; D001741:Black or African American
chemical_list: D002951:Citrates; D019343:Citric Acid