Congenital muscular dystrophy: correlation of muscle biopsy and clinical features.
Six patients with congenital muscular dystrophy examined from January, 1990 to January, 1993 are presented. Vastus lateralis muscle biopsies were performed on all patients. Five of 6 patients had "pure" congenital muscular dystrophy without evidence of central nervous system disease. Of these 5 patients, 2 had mild courses, 2 moderate, and 1 severe. Possible correlation between severity of muscle pathology and severity of clinical course in "pure" congenital muscular dystrophy patients is discussed.
Parano
E
E
Pediatric Clinic of Catania, University of Catania, Italy.
Fiumara
A
A
Falsperla
R
R
Vita
G
G
Trifiletti
R R
RR
D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003238:Connective Tissue / Q000473:pathology; D003241:Consanguinity; D004576:Electromyography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009132:Muscles / Q000473:pathology*; D009133:Muscular Atrophy / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D009136:Muscular Dystrophies / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D009336:Necrosis; D009460:Neurologic Examination