title: Intraligamentary injection of slow-release methylprednisolone for the prevention of pain after endodontic treatment.
abstract: The intraligamentary injection of a slow-release steroidal, the anti-inflammatory agent slow-release methylprednisolone (Depomedrol), was compared to a placebo and to an active placebo (Mepivacaine) in preventing postoperative pain after root canal treatment. The results clearly demonstrated that the tested drug significantly reduced the frequency and intensity of postoperative pain sequelae in the experimental set-up.
authors.affiliation: Hospital Oral Medicine Service, Hebrew University, Hadassah School of Dental Medicine, Jerusalem, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Kaufman
authors.forename: I
authors.initials: I
authors.lastname: Heling
authors.forename: I
authors.initials: I
authors.lastname: Rotstein
authors.forename: S
authors.initials: S
authors.lastname: Friedman
authors.forename: A
authors.initials: A
authors.lastname: Sion
authors.forename: C
authors.initials: C
authors.lastname: Moz
authors.forename: A
authors.initials: A
authors.lastname: Stabholtz
mesh_terms: D000328:Adult; D000368:Aged; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control*; D010485:Periapical Periodontitis / Q000209:etiology / Q000517:prevention & control; D010513:Periodontal Ligament; D012390:Root Canal Therapy / Q000009:adverse effects; D011795:Surveys and Questionnaires
chemical_list: D003692:Delayed-Action Preparations; D008775:Methylprednisolone