title: Conservative initial treatment for liver abscesses in children.
abstract: A total of 124 children aged less than 14 years with a liver abscess were seen in a 16-year period (1974-1990) and treated by non-operative initial management. Of the abscesses 98 occurred in the right liver and 26 in the left. The abscesses were solitary in 93 patients. Overall, 77 of the solitary and 21 of the multiple abscesses were confined to the right liver. In 78 of the right-sided and 20 of the left-sided abscesses the infection was primarily pyogenic in nature with Staphylococcus aureus being the usual organism cultured. The remainder were of amoebic origin. Clinical features were similar in patients with amoebic and pyogenic abscesses. Clinical and ultrasonographic follow-up demonstrated successful non-operative management and healing in 37 per cent of all patients submitted to an initial protocol of medical supportive care and antibiotic therapy. Of the multiple abscesses 60 per cent responded to non-operative management. Fourteen of the 16 solitary left-sided liver abscesses required drainage and three left-sided abscesses ruptured before drainage. Patients with a solitary left-sided abscess warrant early operative intervention.
authors.affiliation: Department of Paediatric Surgery, Institute of Child Health, Cape Town, South Africa.
authors.forename: S W
authors.initials: SW
authors.lastname: Moore
authors.forename: A J
authors.initials: AJ
authors.lastname: Millar
authors.forename: S
authors.initials: S
authors.lastname: Cywes
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000473:pathology / Q000601:surgery; D008100:Liver Abscess / Q000150:complications / Q000473:pathology / Q000628:therapy*; D008101:Liver Abscess, Amebic / Q000150:complications / Q000473:pathology / Q000628:therapy; D008297:Male; D013203:Staphylococcal Infections / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents