title: [The problem of secondary immunodeficiencies in patients with chronic bronchitis].
abstract: The paper concerns the problem of secondary immunodeficiency (SID) in chronic bronchitis (CB) patients. Clinical and laboratory criteria of SID are suggested with clinical illustrations covering 57 cases. SID was diagnosed in 80.7% of the examinees and was associated with reduced quantitative and functional parameters of T-lymphocytes, imbalance in subpopulations of regulatory T-lymphocytes. Observations of the patients during their treatment with immunostimulants showed the changes to be reversible, accompanied frequently with parallel rise in serum immunoglobulins, circulating immune complexes.
authors.forename: V S
authors.initials: VS
authors.lastname: Shirinskiĭ
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Sennikova
mesh_terms: D000917:Antibody Formation; D000936:Antigen-Antibody Complex / Q000097:blood; D001402:B-Lymphocytes / Q000276:immunology; D001991:Bronchitis / Q000175:diagnosis* / Q000276:immunology; D002908:Chronic Disease; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000097:blood; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex; D007136:Immunoglobulins
vernacular_title: Problema vtorichnykh immunodefitsitov u bol'nykh khronicheskim bronkhitom.