title: Classification of alcoholism with reference to comorbidity.
abstract: Classification of individuals with alcoholism is currently limited. The purpose of this analysis was to determine whether antisocial personality disorder and other primary psychiatric syndromes identified subgroups of alcoholics with differing characteristics. Alcoholic probands (n = 224) with alcoholism were divided into those with primary alcoholism (n = 128), antisocial alcoholism (n = 50), and secondary alcoholism (n = 46). These groups were evaluated with regard to alcohol-related symptoms and upon a variety of psychiatric signs and symptoms. The secondary alcoholism. The antisocial alcoholic and primary alcoholic groups demonstrated many similarities, but overall, the antisocial alcoholic group appeared most severe. The antisocial alcoholic group additionally exhibited a dissociation between the subjectively reported and the observed behavior. These findings support the concept of heterogeneity within the alcoholism spectrum. Longitudinal data are needed to determine whether the observed cross-sectional differences predict outcome differences.
authors.affiliation: Department of Veterans Affairs Medical Center, Iowa City, IA.
authors.forename: B L
authors.initials: BL
authors.lastname: Cook
authors.forename: G
authors.initials: G
authors.lastname: Winokur
authors.forename: R C
authors.initials: RC
authors.lastname: Fowler
authors.forename: B I
authors.initials: BI
authors.lastname: Liskow
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000145:classification* / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D000987:Antisocial Personality Disorder / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D015897:Comorbidity; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000145:classification* / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D008875:Middle Aged; D010552:Personality Assessment; D011569:Psychiatric Status Rating Scales