[The serotonin content in human platelets is unstable: data and possible mechanisms].
The study of serotonin content in platelets showed the instability of this trait and its interrelation with plasma serotonin. The oscillations of platelet serotonin are stabilized by the removing of plasma proteins, calcium and by incubation with lithium. The model of synchronization of serotonin transport via the membrane of platelets bound into a spongy net by fibrinogen molecules is discussed.
Karas'
S I
SI
Iazykov
K G
KG
Makarova
E V
EV
Danilets
A V
AV
D001692:Biological Transport / Q000502:physiology; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D001798:Blood Proteins / Q000378:metabolism; D002118:Calcium / Q000097:blood; D006801:Humans; D008094:Lithium / Q000494:pharmacology; D012016:Reference Values; D012701:Serotonin / Q000097:blood*
D001798:Blood Proteins; D012701:Serotonin; D008094:Lithium; D002118:Calcium
Soderzhanie serotonina v trombotsitakh cheloveka nestabil'no: fakty i vozmozhnye mekhanizmy.