title: Phosphorylation of dynamin by cdc2 kinase.
abstract: A 100kD microtubule-bundling protein dynamin was phosphorylated in vitro by cdc2 kinase to approximately 1 mol of phosphate/mol of dynamin at a serine residue. These phosphorylations of dynamin greatly reduced its binding ability to microtubules.
authors.affiliation: Department of Biological Science, Faculty of Science, Hiroshima University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Hosoya
authors.forename: S
authors.initials: S
authors.lastname: Komatsu
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: M
authors.initials: M
authors.lastname: Inagaki
authors.forename: M
authors.initials: M
authors.lastname: Ikegami
authors.forename: K
authors.initials: K
authors.lastname: Yazaki
mesh_terms: D000818:Animals; D001665:Binding Sites; D001923:Brain Chemistry; D016203:CDC2 Protein Kinase / Q000378:metabolism*; D034281:Dynamins; D004591:Electrophoresis, Polyacrylamide Gel; D020558:GTP Phosphohydrolases / Q000737:chemistry / Q000378:metabolism*; D006367:HeLa Cells / Q000201:enzymology; D006801:Humans; D008854:Microscopy, Electron; D008870:Microtubules / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism*; D010766:Phosphorylation; D010768:Phosphoserine / Q000378:metabolism; D051381:Rats
chemical_list: D010710:Phosphates; D010768:Phosphoserine; D016203:CDC2 Protein Kinase; D020558:GTP Phosphohydrolases; D034281:Dynamins