title: Sterile necrosis of the liver due to primary epithelioid haemangio-endothelioma presenting as fever of undetermined origin.
abstract: We report a case of primary epithelioid haemangio-endothelioma of the liver presenting as fever of undetermined origin. Due to the presence of iso-echoic sterile necrosis of the liver no abnormalities were found on four subsequent ultrasonographies of the liver. The definite diagnosis of haemangio-endothelioma was made only after a computerized tomography guided biopsy from the area adjacent to the lesions was stained for Factor VIII. If the latter procedure is omitted, the diagnosis can easily be missed.
authors.affiliation: Department of Internal Medicine II, University Hospital Dijkzigt, Rotterdam, Netherlands.
authors.forename: R A
authors.initials: RA
authors.lastname: de Man
authors.forename: D J
authors.initials: DJ
authors.lastname: Bac
authors.forename: M
authors.initials: M
authors.lastname: van Blankenstein
authors.forename: P E
authors.initials: PE
authors.lastname: Zondervan
mesh_terms: D005335:Fever of Unknown Origin / Q000209:etiology*; D006390:Hemangioendothelioma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009336:Necrosis