title: Simulation of daytime vigilance by the additive interaction of a homeostatic and a circadian process.
abstract: The two-process model of sleep regulation postulates that a homeostatic and a circadian process underlie sleep regulation. The timing of sleep and waking is accounted for by the interaction of these two processes. The assumptions of two separate processes or of a single process resulting from their additive interaction are mathematically equivalent but conceptually different. Based on an additive interaction, subjective alertness ratings in a forced desynchrony protocol and subjective sleepiness ratings in a photoperiod experiment were simulated. The correspondence between empirical and simulated data supports the basic assumption of the model.
authors.affiliation: Institute of Pharmacology, University of Zürich, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Achermann
authors.forename: A A
authors.initials: AA
authors.lastname: Borbély
mesh_terms: D001143:Arousal / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology*; D003491:Cybernetics; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D017440:Photoperiod; D012890:Sleep / Q000502:physiology