title: [Candida chorioretinitis: current therapeutic approach].
abstract: BACKGROUND
  Candida endophthalmitis may occur either during systemic Candida infection (candidemia), particularly in immunocompromised hosts or as a single manifestation in drug abusers.
  
  
  METHODS
  One case of endogenous candida endophthalmitis (ECE) in a patient with systemic candidiasis and four cases of drug abusers are presented. Well confined inflammatory lesions in retina and choroid were adequately treated with systemic Amphotericin B administration, whereas lesion extension beyond the internal limiting membrane towards the vitreous required surgical management, to remove epiretinal fibrovascular tissue, and intravitreal Amphotericin B injection.
  
  
  CONCLUSIONS
  In all cases, treatment resulted to regression of the lesions, however visual function recovery depends on location of chorioretinal lesions.
authors.affiliation: Clinique d'Ophtalmologie H.C.U. Genève.
authors.forename: C J
authors.initials: CJ
authors.lastname: Pournaras
authors.forename: D
authors.initials: D
authors.lastname: Issoua
authors.forename: S
authors.initials: S
authors.lastname: Saravelos
authors.forename: G
authors.initials: G
authors.lastname: Sunaric
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage*; D002177:Candidiasis / Q000188:drug therapy*; D002825:Chorioretinitis / Q000188:drug therapy; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D009877:Endophthalmitis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000188:drug therapy*; D014821:Vitrectomy
chemical_list: D000666:Amphotericin B
vernacular_title: Choriorétinite à candida: approche thérapeutique actuelle.