Cytogenetic findings in seven lacrimal gland neoplasms.
We have undertaken cytogenetic investigation of seven benign and malignant lacrimal gland neoplasms. This study showed recurrent chromosomal abnormalities involving chromosomes 3, 8, 9, and 12. These features are similar to those found in benign and malignant salivary gland tumors, which suggests possible common mechanisms involved in the neoplastic proliferation of these histologically related tumors.
Hrynchak
M
M
Division of Laboratory Medicine, British Columbia Cancer Agency, Vancouver, Canada.
White
V
V
Berean
K
K
Horsman
D
D
D000230:Adenocarcinoma / Q000235:genetics*; D008949:Adenoma, Pleomorphic / Q000235:genetics*; D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000235:genetics*; D002869:Chromosome Aberrations; D002906:Chromosomes, Human, 6-12 and X; D002893:Chromosomes, Human, Pair 3; D005134:Eye Neoplasms / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D007766:Lacrimal Apparatus Diseases / Q000235:genetics*; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000235:genetics