title: [Pemphigus chronicus benignus familiaris (Hailey-Hailey disease) and bipolar affective disease in 3 members of a family].
abstract: We report on three family members suffering from both autosomal dominant Hailey-Hailey disease and bipolar affective disorder. As molecular biology techniques have made the localization of genes causing simple Mendelian traits possible as a routine task, the gene for Hailey-Hailey disease will presumably be localized in the foreseeable future. The Hailey-Hailey gene and its chromosomal surrounding will then be a region of interest for linkage studies in bipolar affective disorder.
authors.affiliation: Haut- und Poliklinik, Rheinisch-Westfälischen Friedrich-Wilhelms Universität Bonn.
authors.forename: M
authors.initials: M
authors.lastname: Wilk
authors.forename: M
authors.initials: M
authors.lastname: Rietschel
authors.forename: J
authors.initials: J
authors.lastname: Körner
authors.forename: H J
authors.initials: HJ
authors.lastname: Möller
authors.forename: M M
authors.initials: MM
authors.lastname: Nöthen
authors.forename: R
authors.initials: R
authors.lastname: Bauer
authors.forename: H W
authors.initials: HW
authors.lastname: Kreysel
mesh_terms: D001706:Biopsy; D001714:Bipolar Disorder / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D002872:Chromosome Deletion; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D016506:Pemphigus, Benign Familial / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D012729:Sex Chromosome Aberrations / Q000175:diagnosis / Q000235:genetics*; D012867:Skin / Q000473:pathology; D014998:Y Chromosome
vernacular_title: Pemphigus chronicus benignus familiaris (Morbus Hailey-Hailey) und bipolare affektive Erkrankung bei drei Mitgliedern einer Familie.