[Experiences with mitomycin C].
BACKGROUND
Recently, encouraging results with the use of Mitomycin C in trabeculectomy have been reported.


METHODS
We used Mitomycin C (0.028%) during trabeculectomy in 72 eyes of 68 patients. Forty-one eyes have already been controlled during 6 months and 19 eyes during 9 months after the surgery.


RESULTS
The mean intraocular pressure after 6 and 9 months was respectively 13 +/- 8 mm Hg and 13 +/- 10 mm Hg. The difference between these results and the preoperative values (27 +/- 9 mm Hg) were statistically significant after 6 and 9 months (p < 0.001). Despite frequent choroidal detachments (20 eyes), the visual acuity recovered during the follow-up to the preoperative values.


CONCLUSIONS
In patients with uncertain prognosis for the intraocular pressure after trabeculectomy, the intraoperative application of Mitomycin C seems to improve considerably the operative success rate.
Gaspar
A Z
AZ
Universitäts-Augenklinik Basel.
Orgül
S
S
Flammer
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage* / Q000009:adverse effects; D009883:Ophthalmic Solutions; D014130:Trabeculectomy / Q000379:methods*; D014792:Visual Acuity / Q000187:drug effects
D009883:Ophthalmic Solutions; D016685:Mitomycin
Erfahrungen mit Mitomycin C.