title: Integrated human genome-wide maps constructed using the CEPH reference panel.
abstract: High resolution linkage maps have proven to be invaluable tools in genetic investigations. We have assembled a collection of genetic maps constructed from primary data collected from investigators performing genotyping using the Centre Etude Polymorphism Humain (CEPH) reference pedigree panel. These maps were constructed using a rigorous, semi-automated map construction algorithm that evaluates the integrity of the maps during construction. Two classes of maps were produced: a high confidence "skeletal" set composed of 544 PCR based markers, and a more highly annotated "framework" set containing maps of 1,123 markers. Genetic map locations within the framework maps are provided for an additional 1,758 loci without statistically unique interval assignments.
authors.affiliation: Division of Population Science, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111.
authors.forename: K H
authors.initials: KH
authors.lastname: Buetow
authors.forename: J L
authors.initials: JL
authors.lastname: Weber
authors.forename: S
authors.initials: S
authors.lastname: Ludwigsen
authors.forename: T
authors.initials: T
authors.lastname: Scherpbier-Heddema
authors.forename: G M
authors.initials: GM
authors.lastname: Duyk
authors.forename: V C
authors.initials: VC
authors.lastname: Sheffield
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: J C
authors.initials: JC
authors.lastname: Murray
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D002877:Chromosomes, Human; D016208:Databases, Factual; D005260:Female; D005602:France; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D007255:Information Services; D008297:Male; D010375:Pedigree; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers