title: [The characteristics of prostaglandin E synthesis in epithelial ovarian tumors].
abstract: Comparative investigation of prostaglandin E (PGE) levels in primary malignant and benign epithelial tumors, metastases, and normal tissue of the ovaries has revealed more significant variations in PGE levels in malignant tumors than in benign ones. PGE content was reliably higher in adenocarcinomas as against benign tumors and normal ovarian tissue. No noticeable differences in PGE levels of benign tumors and normal tissue were revealed. The possibility of using arachidonic acid cyclooxygenase metabolism blockers in therapy of ovarian carcinoma, besides the common methods of treatment, is discussed.
authors.forename: N E
authors.initials: NE
authors.lastname: Kushlinskiĭ
authors.forename: K I
authors.initials: KI
authors.lastname: Zhordania
authors.forename: I G
authors.initials: IG
authors.lastname: Ol'khovskaia
authors.forename: L S
authors.initials: LS
authors.lastname: Bassalyk
authors.forename: V P
authors.initials: VP
authors.lastname: Kozachenko
authors.forename: L T
authors.initials: LT
authors.lastname: Liakina
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000737:chemistry / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000737:chemistry / Q000378:metabolism*; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000378:metabolism*; D010053:Ovary / Q000737:chemistry; D011458:Prostaglandins E / Q000032:analysis / Q000096:biosynthesis*; D011863:Radioimmunoassay; D012016:Reference Values
chemical_list: D011458:Prostaglandins E
vernacular_title: Osobennosti sinteza prostaglandinov serii E v épitelial'nykh opukholiakh iaichnikov.