title: [The spread of hepatitis C markers among the population of regions of Russia and Central Asia].
abstract: A total of 2,217 blood serum samples taken from the population of some regions of the former USSR were studied for the presence of antibodies to hepatitis C virus (HCV) with the use of a commercial enzyme immunoassay system (obtained from Ortho, Japan). Perceptible changes in the detection rate of these antibodies throughout the territory of the former USSR were established. Most frequently anti-HCV antibodies were detected among the population of the republics of Central Asia (5.3-2.9%), as well as Tuva and Yakutia (2.5-3.0%), their lowest detection rate was in Moscow (1.3%). In Moscow the results of the assay in adults were positive twice as frequently as in children, and in donors with an elevated level of alanine-transferase activity the presence of these antibodies was confirmed in 8.9% of cases. The frequency of the confirmation of the presence of anti-HCV antibodies by recombinant immunoblotting was 70.7% in all positive sera and 100% in the sera from a group of donors with an elevated enzyme level. In many respects coincidence between the regularities in the spread of viral hepatitic C and hepatitides B, D was noted.
authors.forename: T L
authors.initials: TL
authors.lastname: Iashina
authors.forename: M O
authors.initials: MO
authors.lastname: Favorov
authors.forename: I V
authors.initials: IV
authors.lastname: Shakhgil'dian
authors.forename: D M
authors.initials: DM
authors.lastname: Iarasheva
authors.forename: O I
authors.initials: OI
authors.lastname: Nazarova
authors.forename: E N
authors.initials: EN
authors.lastname: Derevianko
authors.forename: M I
authors.initials: MI
authors.lastname: Ommadova
authors.forename: G G
authors.initials: GG
authors.lastname: Onishchenko
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: K
authors.initials: K
authors.lastname: Nishioka
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000918:Antibody Specificity; D001209:Asia, Central / Q000453:epidemiology; D015415:Biomarkers / Q000097:blood; D001782:Blood Donors / Q000706:statistics & numerical data; D002648:Child; D002675:Child, Preschool; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006508:Hepatitis Antibodies / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012426:Russia / Q000453:epidemiology; D016036:Seroepidemiologic Studies
chemical_list: D015415:Biomarkers; D006508:Hepatitis Antibodies
vernacular_title: Rasprostranenie markerov gepatita C sredi naseleniia nekotorykh regionov Rossii i Sredneĭ Azii.