[Central pontine myelinolysis: apropos of an oligosymptomatic form].
The authors report a case of paucisymptomatic central pontine myelinolysis (CMP). A 66 years old female had severe hypochloronatremia and hypokaliemia due to diuretic. Despite a slow hydroelectrolytic correction, she presented with dumbness and seizure. CT scan showed hypodensity of protuberance and magnetic resonance imaging (MRI) shown hypersignal of protuberance and undercortex, compatible with central and extra pontine myelinolysis. The long term clinical outcome was good, as MRI's data. Rapid and important correction of severe hyponatremia should be the most important factors of demyelination, secondary to interference with cerebral adaptation mechanisms to hypoosmolality. These factors were not present in this case.
Meyer
P
P
Service de médecine B, hôpitaux de Brabois, CHU de Nancy, France.
Jouanny
P
P
Laurain
M C
MC
Bollaërt
P E
PE
Braun
M
M
Mallié
J P
JP
Jeandel
C
C
D000368:Aged; D004232:Diuretics / Q000009:adverse effects; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D017590:Myelinolysis, Central Pontine / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D011379:Prognosis; D014057:Tomography, X-Ray Computed
D004232:Diuretics
Myélinolyse centropontine: à propos d'une forme paucisymptomatique.