title: Analysis of discrete T2 components of NMR relaxation for aqueous solutions in hollow fiber capillaries.
abstract: An analysis is presented of proton NMR T2 relaxation times measured for aqueous solutions in simple bundles of hollow fibers. The relaxation times are calculated with a two-compartment diffusive exchange model using the known relaxation times of the aqueous solutions and the fiber geometry. When the relaxation time outside the fibers is short (approximately 1 ms), three or more relaxation components are observed from this two compartment system, in agreement with the calculation. The amplitude and relaxation times of the third component are consistent with those of a diffusion-mediated mode, as suggested theoretically by Brownstein and Tarr (Phys. Rev. A 19, 2446 (1979)). The possible contribution of such modes to the multicomponent relaxation observed in tissues is discussed.
authors.affiliation: Department of Medical Biophysics, University of Toronto, Canada.
authors.forename: M J
authors.initials: MJ
authors.lastname: Bronskill
authors.forename: G E
authors.initials: GE
authors.lastname: Santyr
authors.forename: B
authors.initials: B
authors.lastname: Walters
authors.forename: R M
authors.initials: RM
authors.lastname: Henkelman
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002417:Cattle; D004058:Diffusion; D005682:Gadolinium / Q000737:chemistry; D019786:Gadolinium DTPA; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008280:Magnetics; D008567:Membranes, Artificial; D008954:Models, Biological; D008956:Models, Chemical; D009942:Organometallic Compounds / Q000737:chemistry; D004369:Pentetic Acid / Q000031:analogs & derivatives / Q000737:chemistry; D010539:Permeability; D011108:Polymers; D016062:Porosity; D012709:Serum Albumin / Q000737:chemistry; D012996:Solutions / Q000737:chemistry; D013450:Sulfones; D013499:Surface Properties; D014867:Water / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D009942:Organometallic Compounds; D011108:Polymers; D012709:Serum Albumin; D012996:Solutions; D013450:Sulfones; D014867:Water; C017662:polysulfone P 1700; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA