title: Epidemiology of tuberculosis in the United States, 1985 through 1992.
abstract: OBJECTIVE
  To examine the distribution and sources of increased tuberculosis (TB) morbidity in the United States from 1985 through 1992.
  
  
  METHODS
  Review of TB surveillance data.
  
  
  METHODS
  All incident TB cases in the United States reported to the Centers for Disease Control and Prevention from 1980 through 1992.
  
  
  METHODS
  Changes in reported number of TB cases from 1985 through 1992 were analyzed by sex, race/ethnicity, age, county of birth (1986 through 1992), site of disease, geographic location, and socioeconomic status (through 1991). From 1985 through 1992, reported number of cases was compared with expected number of cases, extrapolated from 1980 through 1984 trends, to estimate excess cases by sex, race/ethnicity, and age.
  
  
  RESULTS
  Increases in number of cases from 1985 through 1992 were concentrated among racial/ethnic minorities, persons 25 to 44 years of age, males, and the foreign-born. Excess cases occurred in both sexes, all racial/ethnic groups, and all age groups. Foreign-born cases accounted for 60% of the total increase in the number of US cases from 1986 through 1992 and had the greatest impact among Asians, Hispanics, females, and persons other than those 25 to 44 years of age. Human immunodeficiency virus infection had the greatest impact on TB morbidity among whites, blacks, males, and persons 25 to 44 years of age. From 1985 through 1992, the number of cases among children 4 years old or younger increased 36%, suggesting that transmission of TB increased during this period.
  
  
  CONCLUSIONS
  Multiple factors contributed to the recent increases in the number of TB cases. The effectiveness of TB screening in immigrants needs further evaluation. Intensified efforts to determine the human immunodeficiency virus status of persons with TB are needed. Screening of subpopulations at increased risk for tuberculous infection or TB should be expanded.
authors.affiliation: Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, GA 30333.
authors.forename: M F
authors.initials: MF
authors.lastname: Cantwell
authors.forename: D E
authors.initials: DE
authors.lastname: Snider
authors.forename: G M
authors.initials: GM
authors.lastname: Cauthen
authors.forename: I M
authors.initials: IM
authors.lastname: Onorato
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002487:Centers for Disease Control and Prevention, U.S.; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003710:Demography; D004641:Emigration and Immigration / Q000706:statistics & numerical data; D005260:Female; D015658:HIV Infections / Q000453:epidemiology; D006801:Humans; D007223:Infant; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D012044:Regression Analysis; D017678:Sex Distribution; D012959:Socioeconomic Factors; D014376:Tuberculosis / Q000453:epidemiology*; D014481:United States / Q000453:epidemiology