Interaction between the dominant negative mutant and the wild-type envelope proteins of Friend murine leukemia virus.
Interaction between the previously obtained dominant negative mutant, referred to as fcr (T. Matano, T. Odawara, M. Ohshima, H. Yoshikura, and A. Iwamoto, J. Virol. 67:2026-2033, 1993), and the wild-type envelope proteins (Env) of Friend murine leukemia virus was examined. The wild-type Env was bound to the fcr mutant Env and trapped in the endoplasmic reticulum. The virus receptor was not involved in this interaction.
Matano
T
T
Department of Bacteriology, Faculty of Medicine, University of Tokyo, Japan.
Odawara
T
T
Ohshima
M
M
Iwamoto
A
A
Yoshikura
H
H
D002460:Cell Line; D004721:Endoplasmic Reticulum / Q000378:metabolism; D005622:Friend murine leukemia virus / Q000235:genetics / Q000254:growth & development*; D015686:Gene Products, env / Q000235:genetics / Q000378:metabolism*; D005799:Genes, Dominant; D066298:In Vitro Techniques; D009154:Mutation; D011485:Protein Binding; D014779:Virus Replication
D015686:Gene Products, env