title: Fatal intracerebral hemorrhage following thrombolytic therapy of embolic myocardial infarction in unsuspected infective endocarditis.
abstract: Cerebral hemorrhage occurs in 0.2% of patients under the age of 60 years treated with thrombolytic therapy for acute myocardial infarction. A case of fatal cerebral hemorrhage following TPA therapy for myocardial infarction due to probable coronary artery embolism during unsuspected native valve infective endocarditis is reported.
authors.affiliation: Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
authors.forename: T G
authors.initials: TG
authors.lastname: Di Salvo
authors.forename: S B
authors.initials: SB
authors.lastname: Tatter
authors.forename: P T
authors.initials: PT
authors.lastname: O'Gara
authors.forename: G P
authors.initials: GP
authors.lastname: Nielsen
authors.forename: R W
authors.initials: RW
authors.lastname: DeSanctis
mesh_terms: D002404:Catheterization / Q000009:adverse effects; D002543:Cerebral Hemorrhage / Q000209:etiology*; D003328:Coronary Thrombosis / Q000150:complications; D004697:Endocarditis, Bacterial / Q000150:complications; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
chemical_list: D010959:Tissue Plasminogen Activator