title: Aggressive granulomatosis complicating knee arthroplasty.
abstract: Aggressive granulomatosis is a potentially devastating complication of joint-replacement surgery. This condition likely represents a foreign body reaction to particulate metal, methylmethacrylate or polyethylene. The authors describe a 51-year-old woman in whom aggressive granulomatosis developed after total knee arthroplasty. Plain radiographs over a 3-year period showed progressively expanding focal areas of bone loss. Revision arthroplasty was necessary to prevent pathologic fracture.
authors.affiliation: Department of Radiology, Emory University School of Medicine, Atlanta, GA 30322.
authors.forename: S
authors.initials: S
authors.lastname: Tigges
authors.forename: R G
authors.initials: RG
authors.lastname: Stiles
authors.forename: J R
authors.initials: JR
authors.lastname: Roberson
mesh_terms: D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology*; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging; D007720:Knee Prosthesis / Q000009:adverse effects*; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation