title: Structure, function, and biogenesis of glycosomes in kinetoplastida.
abstract: Glycosomes are intracellular, microbody-like organelles found in all members of the protist order Kinetoplastida examined. Nine enzymes involved in glucose and glycerol metabolism are associated with these organelles. These enzymes are involved in pathways which, in other organisms, are usually located in the cytosol. This paper reviews our current knowledge about the glycosome and its constituent enzymes, with special reference to the organelle of Trypanosoma brucei.
authors.affiliation: Research Unit for Tropical Diseases, International Institute of Cellular and Molecular Pathology, Brussels, Belgium.
authors.forename: V
authors.initials: V
authors.lastname: Hannaert
authors.forename: P A
authors.initials: PA
authors.lastname: Michels
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002451:Cell Compartmentation; D006019:Glycolysis; D016830:Kinetoplastida / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure; D008969:Molecular Sequence Data; D015388:Organelles / Q000201:enzymology / Q000378:metabolism*; D021382:Protein Sorting Signals / Q000235:genetics / Q000378:metabolism; D014346:Trypanosoma brucei brucei / Q000378:metabolism / Q000648:ultrastructure
chemical_list: D021382:Protein Sorting Signals