title: [Mechanisms of action of angiotensin I converting enzyme inhibitors].
abstract: Different mechanisms of action of angiotensin I converting enzyme (ACE) inhibitors are now known. ACE inhibitors can decrease angiotensin II synthesis directly in the tissue. The well known are now renal and vascular renin-angiotensin systems. ACE inhibitors do influence on the blood pressure and proliferation of cardiomyocytes, endothelial and mesangial cells also through activation of the kallikrein-kinin system and production of prostaglandin E, prostacyclin, nitric oxide and medullipin.
authors.affiliation: Katedry i Kliniki Nefrologii, SI.A.M., Katowicach.
authors.forename: A
authors.initials: A
authors.lastname: Wiecek
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology*; D000818:Animals; D006801:Humans; D012084:Renin-Angiotensin System / Q000187:drug effects / Q000502:physiology
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors
vernacular_title: Mechanizmy działania inhibitorów enzymu przekształcajacego angiotensyne I (ACI).