title: [Thyroid function in brain concussion].
abstract: RIA was used to study the quantitative content in the blood serum of thyrotropic (TTH), thyroid (total thyroxine (T4), free thyroxine, triiodothyronine (T3) hormones and thyroxine-binding capacity of blood plasma proteins in 30 patients with brain concussion from the first to the 12th day of disease. The patients' hormonal profile was characterized by normal characteristics of TTH, depression of the transport organic phase of thyroid metabolism with a decrease of the T4 concentration, a reduction of the thyroxine-binding capacity of plasma protein, and simultaneous activation of the peripheral stage of iodine metabolism with excess accumulation in the blood of active hormones--free thyroxine and T3. The data obtained deepen our understanding of the pathogenesis of craniocerebral injury (CCI). The neuroendocrine syndrome identified is specific for mild CCI. It can be used as a differential diagnostic criterion for expert medical evaluation purposes.
authors.forename: A A
authors.initials: AA
authors.lastname: Shutov
authors.forename: A A
authors.initials: AA
authors.lastname: Chudinov
mesh_terms: D000293:Adolescent; D000328:Adult; D001924:Brain Concussion / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D013961:Thyroid Gland / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D013963:Thyroid Hormones
vernacular_title: Funktsional'noe sostoianie shchitovidnoĭ zhelezy pri sotriasenii golovnogo mozga.