title: [Successful neoadjuvant chemotherapy in a patient with advanced gastric cancer with multiple liver metastases].
abstract: We described a case of advanced gastric cancer with multiple liver metastases, who was placed on neoadjuvant chemotherapy using CDDP and 5-FU (FP therapy) with a marked reduction in tumor load. The case was a 67-year-old male, who was admitted with a Borrmann III type advanced gastric cancer with multiple liver metastases. FP chemotherapy was carried out two times as neoadjuvant chemotherapy. As a result, both primary cancer and the metastatic tumors showed a remarkable reduction. Then, total gastrectomy with combined resections of spleen and transverse colon was done, and a reservoir was inserted into the hepatic artery. Postoperatively, intrahepatic arterial infusion of CDDP with oral administration of 5-FU was done in the outpatient clinic for about eleven months. But thirteen months later, he died from the rapid recurrence of the tumor.
authors.affiliation: Dept. of Surgery, Yokohama Central Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Tsuzuki
authors.forename: M
authors.initials: M
authors.lastname: Niki
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.forename: Y
authors.initials: Y
authors.lastname: Takamoto
authors.forename: M
authors.initials: M
authors.lastname: Oohara
authors.forename: K
authors.initials: K
authors.lastname: Mori
authors.forename: S
authors.initials: S
authors.lastname: Igarashi
authors.forename: H
authors.initials: H
authors.lastname: Osada
authors.forename: G
authors.initials: G
authors.lastname: Nishimura
authors.forename: Y
authors.initials: Y
authors.lastname: Kurosu
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008297:Male; D013274:Stomach Neoplasms / Q000628:therapy*
chemical_list: D002945:Cisplatin; D005472:Fluorouracil