title: [Osteo-medullary metastases from cerebral glioblastoma].
abstract: A 55 year old female with a history of three different malignancies including a cerebral glioblastoma developed two bone metastases (in the spine and iliac crest). Histologic and immunohistochemical studies of biopsy specimens demonstrated the presence of glial fibrillary acidic protein, establishing that the bone tumors were metastases from the glioblastoma. Specific features of these rare metastases are discussed.
authors.affiliation: Service de Rhumatologie, CHU de Grenoble.
authors.forename: C
authors.initials: C
authors.lastname: Pireyre
authors.forename: P
authors.initials: P
authors.lastname: Gaudin
authors.forename: I
authors.initials: I
authors.lastname: Falt-Rolachon
authors.forename: B
authors.initials: B
authors.lastname: Pasquier
authors.forename: R
authors.initials: R
authors.lastname: Juvin
authors.forename: X
authors.initials: X
authors.lastname: Phélip
mesh_terms: D001859:Bone Neoplasms / Q000556:secondary*; D001932:Brain Neoplasms / Q000473:pathology*; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D005909:Glioblastoma / Q000473:pathology* / Q000556:secondary; D006801:Humans; D007085:Ilium; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011379:Prognosis; D013125:Spinal Neoplasms / Q000556:secondary*; D013904:Thoracic Vertebrae
chemical_list: D005904:Glial Fibrillary Acidic Protein
vernacular_title: Métastases ostéo-médullaires d'un glioblastome cérébral.