title: Biospecific haemosorbents based on proteinase inhibitor. III. Biospecific antiproteinase haemosorbent 'Ovosorb' in complex therapy of acute destructive pancreatitis.
abstract: Analysis was carried out of the results of complex therapy in 32 patients with acute destructive pancreatitis for which haemosorbtion on Ovosorb, a biospecific antiproteinase haemosorbent containing an immobilized ovomucoid, was used. The clinical efficiency of haemosorbtion was displayed as a decrease in gravity of endogenous intoxication and related functional and metabolic disturbances, as well as in a reduction of lethality from 24.7% to 6.2%.
authors.affiliation: Laboratory of Hemosorbtion of Minsk State Medical Institute, Republic of Belarus.
authors.forename: V V
authors.initials: VV
authors.lastname: Kirkovsky
authors.forename: O F
authors.initials: OF
authors.lastname: Antiperovich
authors.forename: T A
authors.initials: TA
authors.lastname: Valueva
authors.forename: V M
authors.initials: VM
authors.lastname: Moin
authors.forename: G A
authors.initials: GA
authors.lastname: Lobacheva
authors.forename: O G
authors.initials: OG
authors.lastname: Berezkina
mesh_terms: D000208:Acute Disease; D006464:Hemoperfusion; D006801:Humans; D009102:Multiple Organ Failure / Q000628:therapy; D010059:Ovomucin / Q000627:therapeutic use*; D010195:Pancreatitis / Q000097:blood / Q000628:therapy*; D011480:Protease Inhibitors / Q000378:metabolism / Q000627:therapeutic use*
chemical_list: D011480:Protease Inhibitors; C073841:Ovosorb; D010059:Ovomucin