Steroid receptors and orphan receptors in Drosophila development.
Drosophila steroid receptors and related receptor-like proteins show remarkable conservation of structure and function relative to vertebrate homologues. While those proteins are involved in numerous embryonic and post-embryonic developmental processes, a striking number of receptor-like proteins are clustered in regulatory hierarchies under the control of the insect molting hormone ecdysone. This has suggested a number of models based on competitive, cooperative and inter-regulatory interactions between these proteins.
Segraves
W A
WA
Department of Biology, Yale University, New Haven, CT 06511.
D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000378:metabolism; D004330:Drosophila / Q000196:embryology / Q000502:physiology*; D004440:Ecdysone / Q000502:physiology; D008969:Molecular Sequence Data; D011956:Receptors, Cell Surface / Q000502:physiology*; D011987:Receptors, Steroid / Q000502:physiology*; D015398:Signal Transduction; D014157:Transcription Factors / Q000502:physiology*
D011956:Receptors, Cell Surface; D011987:Receptors, Steroid; D014157:Transcription Factors; D004440:Ecdysone; D004247:DNA