title: [Experimental study of anti-radiation effects of interleukin-1 beta].
abstract: Therapeutical effect of human recombinant IL-1 beta on exposed CBA mice was shown. Single injection of IL-1 beta into mice exposed to LD70, LD80 and LD100 raised their 30-day survival by 60, 40 and 35%, respectively. Therapeutically effective doses of IL-1 beta were 100-200 micrograms/kg. Multiple injections of the preparation were ineffective.
authors.forename: S A
authors.initials: SA
authors.lastname: Rogacheva
authors.forename: A S
authors.initials: AS
authors.lastname: Simbirtsev
authors.forename: K N
authors.initials: KN
authors.lastname: Muksinova
mesh_terms: D000818:Animals; D007375:Interleukin-1 / Q000008:administration & dosage / Q000494:pharmacology*; D051379:Mice; D008811:Mice, Inbred DBA; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000401:mortality; D051381:Rats; D013997:Time Factors
chemical_list: D007375:Interleukin-1
vernacular_title: Izuchenie protivoluchevogo deĭstviia interleĭkina-1 beta v éksperimente.