Maxillofacial considerations for diagnosis and treatment in Gorlin's syndrome: access osteotomies for cyst removal and orthognathic surgery.
Gorlin's syndrome is a complex hamartomatous/neoplastic syndrome with multisystemic manifestations involving the skin, central nervous system, and bony skeleton. The purpose of this article is to describe how a patient with Gorlin's syndrome was managed with a multipronged approach that included exposure osteotomies for keratocyst removal combined with orthognathic surgery. This case demonstrates the advantages of standard maxillofacial osteotomies to gain access for the removal of odontogenic cysts and benign tumors.
Posnick
J C
JC
Department of Surgery, Georgetown University Medical Center, Washington, DC 20007.
Clokie
C M
CM
Goldstein
J A
JA
D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D001860:Bone Plates; D003131:Combined Modality Therapy; D005153:Facial Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D007571:Jaw Diseases / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008297:Male; D008313:Malocclusion, Angle Class III / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009807:Odontogenic Cysts / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D010027:Osteotomy / Q000379:methods*; D010348:Patient Care Team; D012867:Skin / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014071:Tooth Abnormalities / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D014095:Tooth, Impacted / Q000175:diagnosis / Q000473:pathology / Q000601:surgery