Constituents of euphorbiaceae 12. Comm. (1). Isolation and structure elucidation of four new cerebrosides from Euphorbia biglandulosa Desf.
Four new cerebrosides 4-6 were isolated from the latex of Euphorbia biglandulosa Desf. and their structures determined. Normal and reverse-phase flash chromatography was effective for the isolation of the cerebrosides, and FAB-MS spectrometry, 1H-NMR, 13C-NMR, DQF-COSY and HMQC experiments and chemical reactions were useful in elucidating their structure. EI-MS of the dimethyl disulfide derivatives of the long chain bases and glucosphingoside-heptaacetates was decisive for the determination of the double bond position on the long chain parts.
Falsone
G
G
Department of Pharmaceutical Sciences, University of Trieste.
Cateni
F
F
Visintin
G
G
Lucchini
V
V
Wagner
H
H
Seligmann
O
O
D002554:Cerebrosides / Q000737:chemistry*; D002845:Chromatography; D007840:Latex / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment
D002554:Cerebrosides; D007840:Latex