title: [The clinical and microbiological study of the preparation perfloxacin in treating urologic infections].
abstract: Experience with Pefloxacin treatment of thirty-nine patients presenting urinary tract infection, over the period 1992-1993, is shared. The drug is administered per os at dosage--800 mg, divided in two doses given at 12-hour intervals. As shown by the results of assaying the clinical symptoms, laboratory indicators and microbiological findings in the urine, the therapeutic effect is very good. A clinical cure is recorded in 76 cases (92 per cent), and healing of the bacteriological agent--in 92.31 per cent. Side effects are rarely observed and mildly manifested. The results of Pefloxacin treatment warrant the assumption that the drug synthesized is encouraging, suitable for both out- and inpatient treatment of urinary tract infections, and therefore it should be introduced in the daily routine practice.
authors.forename: D
authors.initials: D
authors.lastname: Dragiev
authors.forename: E
authors.initials: E
authors.lastname: Savov
authors.forename: A
authors.initials: A
authors.lastname: Lilov
authors.forename: Z
authors.initials: Z
authors.lastname: Tsenova
authors.forename: I
authors.initials: I
authors.lastname: Saltirov
authors.forename: I
authors.initials: I
authors.lastname: Atanasova
mesh_terms: D042462:4-Quinolones; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D001437:Bacteriuria / Q000188:drug therapy / Q000382:microbiology; D004361:Drug Tolerance; D024841:Fluoroquinolones; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015363:Quinolones / Q000009:adverse effects / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D015366:Pefloxacin
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D015366:Pefloxacin
vernacular_title: Klinichno i mikrobiologichno prouchvane na preparata pefloksatsin pri lechenie na uroinfektsiite.