title: Mohs micrographic excision of sebaceous carcinoma of the eyelids.
abstract: BACKGROUND
  Sebaceous carcinoma of the eyelid is a difficult tumor to manage because of diagnostic difficulties and pagetoid-type spread in the conjunctivae.
  
  
  OBJECTIVE
  We report our experience with eight patients using the Mohs technique of excision with reconstruction.
  
  
  METHODS
  Six cases were managed with paraffin-embedded hematoxylin and eosin sections. One case was managed by frozen histologic sections and one was managed with frozen section processing followed by paraffin-embedded section review.
  
  
  RESULTS
  The correct pathologic diagnosis was made initially in only 50% of the cases. Eighty-eight percent of the cases revealed intraepithelial neoplasm. There has been one recurrence with metastatic disease. The average follow-up period has been 56.8 months.
  
  
  CONCLUSIONS
  We advocate early recognition and excision with the Mohs technique with paraffin-embedded sections followed by reconstruction. The use of paraffin-embedded histologic sections helps with interpretation of intraepithelial and pagetoid tumor spread.
authors.affiliation: Mohs Cutaneous Surgery, Scripps Clinic and Research Foundation, La Jolla, California.
authors.forename: A B
authors.initials: AB
authors.lastname: Yount
authors.forename: D
authors.initials: D
authors.lastname: Bylund
authors.forename: S G
authors.initials: SG
authors.lastname: Pratt
authors.forename: H T
authors.initials: HT
authors.lastname: Greenway
mesh_terms: D018266:Adenocarcinoma, Sebaceous / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005142:Eyelid Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D015580:Mohs Surgery