Controlling chaos in the brain.
In a spontaneously bursting neuronal network in vitro, chaos can be demonstrated by the presence of unstable fixed-point behaviour. Chaos control techniques can increase the periodicity of such neuronal population bursting behaviour. Periodic pacing is also effective in entraining such systems, although in a qualitatively different fashion. Using a strategy of anticontrol such systems can be made less periodic. These techniques may be applicable to in vivo epileptic foci.
Schiff
S J
SJ
Department of Neurosurgery, Children's National Medical Center, Washington, DC.
Jerger
K
K
Duong
D H
DH
Chang
T
T
Spano
M L
ML
Ditto
W L
WL
D000200:Action Potentials; D000818:Animals; D004558:Electric Stimulation; D005260:Female; D006624:Hippocampus / Q000502:physiology*; D066298:In Vitro Techniques; D008959:Models, Neurological; D009415:Nerve Net; D017711:Nonlinear Dynamics; D010507:Periodicity; D051381:Rats; D017207:Rats, Sprague-Dawley