title: Dosimetric considerations of commercially fabricated esophageal applicators.
abstract: Two commercially fabricated esophageal applicators for low dose rate intraluminal brachytherapy were compared using the dose non-uniformity ratio (DNR). One of the applicators has a single afterloading catheter while the other applicator has six afterloading catheters to accommodate low dose rate 192Ir ribbon or wire sources. Five sets of source configurations, each with a different ribbon length in the range of 5-17 cm were analysed using the DNR. The DNR shows the delivery of relatively higher total doses at higher dose rates to tissues closer to the applicators. The difference in the inhomogeneity of dose rates and the treatment volume exposed to higher dose rates than the prescribed dose rate between the two applicators are minimal. The dose homogeneity is better for the single-source applicator while the worst dose homogeneity for the six-source applicator is caused by the placement of each source closer to the surface of the applicator. The implications of higher dose rates were discussed using the alpha/beta model.
authors.affiliation: Division of Radiation Oncology, West Virginia University School of Medicine, Morgantown 26506-8150.
authors.forename: C B
authors.initials: CB
authors.lastname: Saw
authors.forename: L J
authors.initials: LJ
authors.lastname: Korb
authors.forename: E R
authors.initials: ER
authors.lastname: Cano
authors.forename: A
authors.initials: A
authors.lastname: Wu
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods*; D004307:Dose-Response Relationship, Radiation; D004947:Esophagus / Q000528:radiation effects; D006801:Humans; D008962:Models, Theoretical; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy