title: [The structural-functional changes in the hepatobiliary system of patients with colorectal cancer].
abstract: On the grounds of clinical and experimental data on hepatobiliary system obtained by hepatobiliscintigraphy (HBSG) and morphological study of hepatic parenchyma deterioration of hepatocytes and suppression of concentrating abilities of gallbladder were found in 68 patients with colorectal cancer and no clinical and laboratory manifestation. Any antitumor treatment, especially combined with chemotherapy, aggravates the disorders. Surgical intervention provokes transient ciliary dyskinesia. Unspecific reactive hepatitis associated with intrahepatic cholestasis and aggravated by antitumor therapy should be considered as a morphological ground for the functional changes. HBSG is recommended to be performed from time to time during post-operative rehabilitation of patients who underwent radical surgery for colorectal cancer. Correction of revealed disorders should be carried out in gastroenterological departments.
authors.forename: I M
authors.initials: IM
authors.lastname: Dykan
authors.forename: H S
authors.initials: HS
authors.lastname: Moroz
authors.forename: H I
authors.initials: HI
authors.lastname: Klymniuk
authors.forename: D O
authors.initials: DO
authors.lastname: Dzhuzha
authors.forename: M M
authors.initials: MM
authors.lastname: Firsova
authors.forename: V I
authors.initials: VI
authors.lastname: Dutko
authors.forename: V M
authors.initials: VM
authors.lastname: Bobko
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001659:Biliary Tract / Q000000981:diagnostic imaging / Q000503:physiopathology*; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007098:Imino Acids; D008099:Liver / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019780:Technetium Tc 99m Lidofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019780:Technetium Tc 99m Lidofenin
vernacular_title: Strukturno-funktsional'ni zminy hepatobiliarnoï systemy u khvorykh na kolorektal'nyĭ rak.