Cytogenetic findings in a new case of adenoid cystic carcinoma arising in sphenoidal sinus.
We studied a case of adenoid cystic carcinoma. Cytogenetic analysis was performed on short-term culture, and the karyotype revealed only an abnormal cell line with the following changes: partial trisomy 5q, 6q deletion, monosomy of chromosome 9,der(10)t(10;15), a possible ring chromosome 22, and loss of the Y chromosome. The implication of chromosomes 6 and 9 is considered in relation to the karyotypic evolution of this type of tumor.
López-Ginés
C
C
Department of Pathology, University of Valencia, Spain.
Cerdá-Nicolás
M
M
Llombart-Bosch
A
A
D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations; D006801:Humans; D007621:Karyotyping; D008297:Male; D010255:Paranasal Sinus Neoplasms / Q000235:genetics* / Q000473:pathology; D013101:Sphenoid Sinus / Q000473:pathology