[Cerebral, central and intracardiac hemodynamics in patients with progressive arterial hypertension following the surgical suppression of adrenal hyperfunction].
Forty-eight patients with progressive (malignant) arterial hypertension resistant to conservative therapy were subjected to surgical portalization of the adrenal blood stream in order to metabolize excessively produced aldosterone in the liver of the patients. Cerebral hemodynamics was studied before by tetra- and bipolar rheoencephalography, central hemodynamics was studied by tetrapolar transthoracic rheography, and intracardiac hemodynamics by echocardiography before and after surgery; blood plasma aldosterone and hydrocortisone concentrations and plasma renin activity were measured. A significant reduction of arterial pressure, elimination or alleviation of subjective and objective manifestations of chronic hypertensive encephalopathy were seen in the majority of patients after surgery. Cerebral blood flow improved, blood plasma aldosterone and renin activity reduced, myocardial hypertrophy decreased, and a trend to normalization of intracardiac hemodynamics was observed.
Burtsev
E M
EM
Lagerev
L M
LM
Kogan
A S
AS
Kulikov
L K
LK
Nepomniashchikh
V A
VA
D000308:Adrenocortical Hyperfunction / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D000328:Adult; D001921:Brain / Q000503:physiopathology*; D004452:Echocardiography; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D006974:Hypertension, Malignant / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012084:Renin-Angiotensin System / Q000502:physiology; D013997:Time Factors
Sostoianie tserebral'noĭ, tsentral'noĭ i vnutriserdechnoĭ gemodinamiki u bol'nykh progressiruiushcheĭ arterial'noĭ gipertenzieĭ posle khirurgicheskogo podavleniia giperfunktsii nadpochechnikov.