title: Hair fibrous protein compositions in some hereditary hair abnormalities determined by two-dimensional polyacrylamide gel electrophoresis.
abstract: S-carboxymethylated (SCM) fibrous proteins (FPs) from the scalp hairs of the three different hereditary hair abnormalities (trichorrhexis invaginata in Netherton's syndrome, pili trianguli et canaliculi in uncombable hair syndrome, and fine hair in anhidrotic ectodermal dysplasia) were analyzed by two-dimensional polyacrylamide gel electrophoresis. Comparison of the SCM FP compositions of the three hair abnormalities with that of the normal revealed that the SCM FP compositions of these three abnormal hairs were all electrophoretically different from each other and that of the normal.
authors.affiliation: Department of Dermatology, Shimane Medical University, Izumo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Koike
authors.forename: S
authors.initials: S
authors.lastname: Dekio
authors.forename: J
authors.initials: J
authors.lastname: Jidoi
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshimura
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: T
authors.initials: T
authors.lastname: Hamada
authors.forename: R
authors.initials: R
authors.lastname: Saito
mesh_terms: D002648:Child; D002675:Child, Preschool; D000013:Congenital Abnormalities / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006197:Hair / Q000002:abnormalities* / Q000737:chemistry; D006801:Humans; D008297:Male; D011506:Proteins / Q000032:analysis*
chemical_list: D011506:Proteins