title: [Circumscribed erythema after cardiac pacemaker implantation].
abstract: The pathological reactions of the tissue under the picture of a circumscriptive erythema above the pacemaker-pouch of a 35-year-old patient was noticed and documented for more than 10 years. Repeated appearance of a painful and fluctuating swelling above the silicone-containing implant, as well as non-symptomatic intervals during times without application of silicone-material led to the assumption of an allergic contact dermatitis to the silicone components of the pacemaker. However, patch-testing of the pacemaker's constituents remained negative and could not verify this supposition. The diagnosis of a foreign-body-reaction was histologically set up. In its progress a stenosis of vessels as well as an activation of the T-cell-system can follow. Therefore, it might be possible that different factors meshing with each other can modify the cause-consequence-structure and can lead to the erythematic changes.
authors.affiliation: Medizinische Klinik I, Krankenhaus Düren (Lehrkrankenhaus der RWTH Aachen).
authors.forename: E
authors.initials: E
authors.lastname: Maushagen
authors.forename: B
authors.initials: B
authors.lastname: Reichle
authors.forename: H
authors.initials: H
authors.lastname: Simon
mesh_terms: D000328:Adult; D001919:Bradycardia / Q000473:pathology / Q000628:therapy*; D017449:Dermatitis, Allergic Contact / Q000209:etiology* / Q000473:pathology; D004890:Erythema / Q000209:etiology* / Q000473:pathology; D005500:Follow-Up Studies; D005549:Foreign-Body Reaction / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial; D010369:Pectoralis Muscles / Q000473:pathology; D011474:Prosthesis Design; D012008:Recurrence; D012804:Sick Sinus Syndrome / Q000473:pathology / Q000628:therapy*; D012828:Silicones / Q000009:adverse effects*
chemical_list: D012828:Silicones
vernacular_title: Zirkumskriptes Erythem nach Herzschrittmacherimplantation.