Effect of GSH depletion mediated by l-BSO on the insecticidal activity of DDT and fenitrothion in Triatoma infestans (Hemiptera).
l-BSO injected at a sublethal dose in nymph V of Triatoma infestans produces a transient GSH depletion in the abdomen. A depletion of the total content of GSH was observed in nymph II fed with a sublethal concentration of l-BSO. Either ingestion or injection pretreatments of T. infestans nymph V with sublethal concentrations of l-BSO produced a slight synergism on the toxicity of fenitrothion. Feeding administration of a sublethal concentration of l-BSO to nymphs II of T. infestans resulted in a weak potentiation of the acute toxicity of DDT.
Fontán
A
A
Centro de Investigaciones de Plagas e Insecticidas, CIPEIN- (CITEFA-CONICET), Buenos Aires, Argentina.
Picollo
M I
MI
Masuh
H
H
Zerba
E
E
D000818:Animals; D019328:Buthionine Sulfoximine; D003634:DDT / Q000633:toxicity*; D005278:Fenitrothion / Q000633:toxicity*; D005978:Glutathione / Q000378:metabolism*; D008717:Methionine Sulfoximine / Q000031:analogs & derivatives* / Q000494:pharmacology; D010574:Pesticide Synergists / Q000494:pharmacology*; D014224:Triatoma / Q000187:drug effects* / Q000378:metabolism
D010574:Pesticide Synergists; D008717:Methionine Sulfoximine; D019328:Buthionine Sulfoximine; D003634:DDT; D005978:Glutathione; D005278:Fenitrothion