title: [Molecular epidemiology of Neisseria gonorrhoeae: effect of sex and sexual orientation on the distribution of gonococcal types].
abstract: Auxotype/serovar (A/S) classification enables precise characterisation of Neisseria gonorrhoeae. In the present study we evaluated whether sex and sexual preference of the patient influence the auxotype/serovar class of the infecting gonococcal strain. In male patients prototrophic/IB-3 was the most frequently isolated A/S class. By contrast, in female patients the A/S class (P)AH(U)/IA-1/2 was significantly (p < 0.005) more frequently isolated than in male patients. Analysis of our data according to sexual preference of the patients showed that in heterosexual patients the two mentioned A/S classes were leading, whereas in homo- and bisexual patients A/S classes prototrophic/IB-2 (p < 0.0001) and Pro/IB-2/16 (p < 0.0001) were isolated significantly more often. Our data are a strong indication that the host environment is also responsible for the selection of N. gonorrhoeae strains with certain typing characteristics.
authors.affiliation: Universitäts-Hautklinik, Ruprecht-Karls-Universität Heidelberg.
authors.forename: P K
authors.initials: PK
authors.lastname: Kohl
authors.forename: I
authors.initials: I
authors.lastname: Henze
authors.forename: I
authors.initials: I
authors.lastname: Kamionek
authors.forename: D
authors.initials: D
authors.lastname: Krahl
authors.forename: D
authors.initials: D
authors.lastname: Petzoldt
mesh_terms: D000328:Adult; D001431:Bacteriological Techniques; D001727:Bisexuality; D003470:Culture Media; D005260:Female; D005858:Germany; D006069:Gonorrhea / Q000145:classification / Q000635:transmission*; D006716:Homosexuality; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000145:classification*; D012703:Serotyping; D012725:Sexual Behavior
chemical_list: D003470:Culture Media
vernacular_title: Molekulare Epidemiologie von Neisseria gonorrhoeae: Einfluss von Geschlecht und sexueller Orientierung auf die Verteilung der Gonokokkentypen.