title: [Significance of trans-fatty acids for health].
abstract: Trans fatty acids make up 0-30% of the fatty acids in Danish margarines. The intake of trans fatty acids from margarine in Denmark was in 1991 on average about 2.5 gram/person/day, and for about 150,000 Danes more than 5 gram/person/day. Several recent case-control studies and a large cohort study as well as clinical ward studies suggest that the intake of trans fatty acids enhances atherogenesis to the same extent or possibly even more than saturated fatty acids. In addition a few studies suggest that the intake of trans fatty acids by the pregnant mother impairs growth of the human foetus. On this background it seems reasonable to reduce the intake of trans fatty acids as much as possible. This could be implemented by a reduction in the fat content of the diet together with a reduction of trans fatty acid content to less than 5% in all margarines. This would ensure that Danes--including pregnant and nursing women--with a high intake of margarine on average consume less than 2 gram of trans fatty acids of vegetables origin per day. This amount corresponds to intake in low risk groups in several studies.
authors.forename: S
authors.initials: S
authors.lastname: Stender
authors.forename: J
authors.initials: J
authors.lastname: Dyerberg
authors.forename: G
authors.initials: G
authors.lastname: Hølmer
authors.forename: L
authors.initials: L
authors.lastname: Ovesen
authors.forename: B
authors.initials: B
authors.lastname: Sandström
mesh_terms: D003718:Denmark; D004041:Dietary Fats / Q000008:administration & dosage* / Q000009:adverse effects; D005227:Fatty Acids / Q000008:administration & dosage* / Q000009:adverse effects / Q000737:chemistry; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D012307:Risk Factors
chemical_list: D004041:Dietary Fats; D005227:Fatty Acids
vernacular_title: Transfedtsyrers betydning for sundheden.