Fatal intracerebral hemorrhage following thrombolytic therapy of embolic myocardial infarction in unsuspected infective endocarditis.
Cerebral hemorrhage occurs in 0.2% of patients under the age of 60 years treated with thrombolytic therapy for acute myocardial infarction. A case of fatal cerebral hemorrhage following TPA therapy for myocardial infarction due to probable coronary artery embolism during unsuspected native valve infective endocarditis is reported.
Di Salvo
T G
TG
Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
Tatter
S B
SB
O'Gara
P T
PT
Nielsen
G P
GP
DeSanctis
R W
RW
D002404:Catheterization / Q000009:adverse effects; D002543:Cerebral Hemorrhage / Q000209:etiology*; D003328:Coronary Thrombosis / Q000150:complications; D004697:Endocarditis, Bacterial / Q000150:complications; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
D010959:Tissue Plasminogen Activator