[Pharmacotherapy of headache with special reference to migraine].
Drug therapy is only one possibility to treat headache or migraine. In a migraine attack aspirin, acetaminophen, non-steroidal antiinflammatory drugs like ibuprofen, naproxen and mefenamic acid are used. Further more weak opiates, caffeine, metoclopramide and the new 5-HT1-receptor agonist sumatriptan are effective in the attack. Ergotamine and dihydroergotamine are probably the most effective though their side effects are troublesome. For prophylactic treatment, the beta-adrenergic receptor blockers propranolol, metoprolol and atenolol are the drugs of first choice. Also calcium channel antagonists like flunaricine and antidepressant drugs like amitryptiline and doxepine are used.
Beubler
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Institut für experimentelle und klinische Pharmacokologie, Karl-Franzens-Universität, Graz.
D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D004878:Ergotamine / Q000009:adverse effects / Q000627:therapeutic use*; D006261:Headache / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy* / Q000209:etiology
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004878:Ergotamine
Pharmakotherapie des Kopfschmerzes unter besonderer Berücksichtigung der Migräne.