Alpha-2-HS-glycoprotein gene frequencies in Basques.
The genetic polymorphism of human alpha 2-HS-glycoprotein (AHSG) was analyzed in a sample of 736 native individuals from the three provinces of the Basque Autonomous Community (Guipúzcoa, Vizcaya and Alava). The Basque population shows the highest frequency of the allele AHSG*3 described to date in European populations. The same is not true for the frequency of allele AHSG*2, which fits well into the genocline described in Europe, in accordance with the adaptive hypothesis.
Aguirre
A
A
Departamento de Biología Animal y Genética, Universidad del País Vasco, Bilbao, España.
Sanz
P
P
Osaba
L
L
Manzano
C
C
Estomba
A
A
Mazon
L
L
de la Rua
C
C
Vicario
A
A
D000483:Alleles; D001798:Blood Proteins / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D010641:Phenotype; D013030:Spain; D060749:alpha-2-HS-Glycoprotein
C556354:AHSG protein, human; D001798:Blood Proteins; D060749:alpha-2-HS-Glycoprotein