[Isopropoxyhermatran--a stimulant of hepatocyte regeneration].
It was shown that isoproxihermatran (IPH) (40 mg/kg) administered intraperitoneally in rats with lobectomy of heparin stimulates development of hepatocytes' dimensions and decrease of oxygen transmission velocity through the mitochondrial membranes in this cells. Antioxidant properties of IPH have been detected. Stimulating activity of IPH at heparin secretion of bile.
Rasulov
M M
MM
Kuznetsov
I G
IG
Shakirova
R G
RG
Zabozlaev
A G
AG
Belousov
A A
AA
Voronkov
M G
MG
D000818:Animals; D001646:Bile / Q000378:metabolism; D048429:Cell Size / Q000187:drug effects; D004579:Electron Transport / Q000187:drug effects; D007399:Interphase / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008115:Liver Regeneration / Q000187:drug effects*; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism; D008938:Mitosis / Q000187:drug effects; D009570:Nitriles / Q000494:pharmacology*; D009942:Organometallic Compounds / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats
D009570:Nitriles; D009942:Organometallic Compounds; C060353:isopropoxygermatrane
Izopropksigermatran--stimuliator regeneratsii gepatotsitov.