title: Effective reduction of LDL cholesterol by indigenous plant product.
abstract: A herbal powder containing guar gum, methi, tundika and meshasringi was administered to 30 control and 30 type 2 (non-insulin dependent) diabetes mellitus patients for a month. Total serum cholesterol and its fractions eg, high density lipoprotein, low density lipoproteins, very low density lipoproteins and serum triglyceride were determined before and after the trial period. Total and low density lipoprotein (LDL) cholesterols were reduced significantly after the therapy. There were no significant changes in high density lipoproteins (HDL), very low density lipoproteins (VLDL) or triglyceride levels. Side-effects eg, mild flatulence and looseness of bowel were noticed in less than 40% cases.
authors.affiliation: Department of Medicine, Indira Gandhi Medical College, Shimla.
authors.forename: P K
authors.initials: PK
authors.lastname: Bhardwaj
authors.forename: D J
authors.initials: DJ
authors.lastname: Dasgupta
authors.forename: B S
authors.initials: BS
authors.lastname: Prashar
authors.forename: S S
authors.initials: SS
authors.lastname: Kaushal
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D015243:Cholesterol, VLDL / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000178:diet therapy; D004043:Dietary Fiber; D005260:Female; D005527:Food, Fortified; D005685:Galactans / Q000008:administration & dosage*; D006801:Humans; D019684:Magnoliopsida; D008297:Male; D008351:Mannans / Q000008:administration & dosage*; D008875:Middle Aged; D053149:Plant Gums; D011208:Powders; D013997:Time Factors; D014280:Triglycerides / Q000097:blood*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D004043:Dietary Fiber; D005685:Galactans; D008351:Mannans; D053149:Plant Gums; D011208:Powders; D014280:Triglycerides; D002784:Cholesterol; C007894:guar gum