Subregional mapping of the human lymphocyte-specific protein tyrosine kinase gene (LCK) to 1p35-->p34.3 and its position relative to the 1p marker D1S57.
The LCK gene encodes a lymphocyte-specific member of the Src family of protein tyrosine kinases. This gene was previously assigned to human chromosome region 1p35-->p32 by isotopic in situ hybridization. We report here its more refined localization to bands 1p35-->p34.3 by fluorescence in situ hybridization on R-banded metaphase chromosomes and its mapping relative to the reference marker pYNZ2 (D1S57).
Volpi
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Istituto di Genetica Molecolare del CNR, Porto Conte Research and Training Laboratories, Alghero, Italy.
Romani
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Siniscalco
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D001483:Base Sequence; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D005819:Genetic Markers; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D019860:Lymphocyte Specific Protein Tyrosine Kinase p56(lck); D008214:Lymphocytes; D008969:Molecular Sequence Data; D011505:Protein-Tyrosine Kinases / Q000235:genetics*
D005819:Genetic Markers; D011505:Protein-Tyrosine Kinases; D019860:Lymphocyte Specific Protein Tyrosine Kinase p56(lck)