title: [Hormonal regulation during cardiac surgery operations on the "dry" heart].
abstract: Central and peripheral compartments of hypophyseo-adrenal regulation, the state of renin-angiotensin-aldosterone system (RAAS) and thyroid-stimulating functions of hypophysis have been assessed in 72 patients with heart valve defects operated under profound hypothermal perfusion. It has been established that cardiopulmonary bypass surgery with profound hypothermia is accompanied by moderate and reversible changes in the above parameters. The activity of hypophyseo-adrenal system and RAAS reaches the maximum during a warming-up period and then gradually decreases. TSH content considerably decreases in the early postoperative period. Cardiopulmonary bypass surgery with profound hypothermia causes more pronounced changes in neurohormonal regulation than heart valve correction under hypothermal perfusion, which might be associated with blood flow arrest in major vessels causing changes in peripheral metabolic processes.
authors.forename: E E
authors.initials: EE
authors.lastname: Litasova
authors.forename: A N
authors.initials: AN
authors.lastname: Malygina
authors.forename: I I
authors.initials: II
authors.lastname: Evnina
authors.forename: G A
authors.initials: GA
authors.lastname: Tsvetovskaia
authors.forename: R P
authors.initials: RP
authors.lastname: Korotkova
authors.forename: E V
authors.initials: EV
authors.lastname: Uglova
mesh_terms: D000293:Adolescent; D001831:Body Temperature; D006348:Cardiac Surgical Procedures; D002648:Child; D002675:Child, Preschool; D006330:Heart Defects, Congenital / Q000097:blood / Q000601:surgery; D006728:Hormones / Q000097:blood*; D006801:Humans; D007036:Hypothermia, Induced; D007432:Intraoperative Period; D013997:Time Factors
chemical_list: D006728:Hormones
vernacular_title: Sostoianie gormonal'noĭ reguliatsii pri kardiokhirurgicheskikh operatsiiakh v usloviiakh "sukhogo" serdtsa.