Stimulatory effects of the central amygdaloid nucleus on pancreatic exocrine secretion in rats.
The effects of electrical stimulation of the central (CE) and basolateral (BL) amygdaloid nuclei on pancreatic exocrine secretion were tested in urethane-anesthetized rats. Electrical stimulation (0.1 mA, 1 ms, 40 Hz) of the CE significantly increased basal and hormone (secretin+cholecystokinin-8)-infused pancreatic exocrine secretion. These increases in pancreatic secretion were abolished by bilateral vagotomy. Electrical stimulation of the BL had no significant effect on basal and hormone-infused secretion. We conclude that the CE plays a stimulatory role in pancreatic exocrine secretion via the vagus nerve but the BL does not affect pancreatic secretion.
Hahn
S J
SJ
Department of Physiology, Catholic University Medical College, Seoul, Korea.
Yoon
S H
SH
Sim
S S
SS
Rhie
D J
DJ
Jo
Y H
YH
Kim
M S
MS
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D004558:Electric Stimulation; D004566:Electrodes; D008297:Male; D010179:Pancreas / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism; D051381:Rats; D014628:Vagotomy
D011506:Proteins