title: Ephedrine enhances analgesic effect of morphine.
abstract: Morphine-ephedrine interaction on analgesia was studied in mice (n = 240) and in post-operative patients (n = 32). It was found that combining morphine and ephedrine enhances analgesia which is not significantly different from the effect of morphine given alone at double dose.
authors.affiliation: Department of Pharmacology, Erciyes University, Medical Faculty, Kayseri, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Tekol
authors.forename: E
authors.initials: E
authors.lastname: Tercan
authors.forename: A
authors.initials: A
authors.lastname: Esmaoğlu
mesh_terms: D000328:Adult; D000698:Analgesia; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001842:Bone and Bones / Q000601:surgery; D004311:Double-Blind Method; D004357:Drug Synergism; D004809:Ephedrine / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D009020:Morphine / Q000008:administration & dosage / Q000494:pharmacology*; D009619:Nociceptors / Q000187:drug effects; D010149:Postoperative Pain / Q000517:prevention & control; D010919:Placebos; D011930:Reaction Time / Q000187:drug effects; D012119:Respiration / Q000187:drug effects
chemical_list: D010919:Placebos; D009020:Morphine; D004809:Ephedrine