title: Application of minimal spanning trees in glioma grading--a CLIPPER program for the calculation and construction of minimal spanning trees.
abstract: We present a CLIPPER program for the calculation and graphical representation of minimal spanning trees (MST) which is available on request on diskette from the authors. The MST are a useful parameter for structural cluster detection. They can be applied to grading problems in tumour biology. We present and discuss the applicability of MST by an example from the field of astrocytoma grading.
authors.affiliation: Department of Neuropathology, Medical School of University of the Saarland, Homburg, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Kolles
authors.forename: H
authors.initials: H
authors.lastname: Ludt
authors.forename: G H
authors.initials: GH
authors.lastname: Vince
authors.forename: W
authors.initials: W
authors.lastname: Feiden
mesh_terms: D000465:Algorithms; D001254:Astrocytoma / Q000473:pathology*; D016000:Cluster Analysis; D003196:Computer Graphics; D006801:Humans; D007091:Image Processing, Computer-Assisted; D011381:Programming Languages; D012044:Regression Analysis; D012984:Software; D012985:Software Design