[Effects of polyunsaturated fatty acids of the omega-3 family in the anti-atherosclerotic diet on the activity of lysosomal lipolytic enzymes, mononuclear cells and blood platelets of patients with ischemic heart disease].
Prior to diet therapy, CHD patients exhibited marked impairment of the system of platelet and mononuclear lysosomal lipolytic enzymes compared to those in healthy controls. A reduced ratio of polyunsaturated fatty acids omega-6/omega-3 in low-sodium hypolipidemic diet (from 10.3 to 6.3-1.3) incorporating halibut flesh and ichthyoic oil promoted its antiatherogenic efficacy. The activity of platelet and mononuclear lysosomal lipolytic enzymes and lipid spectrum in coronary patients returned to normal values.
Tutel'ian
V A
VA
Samsonov
M A
MA
Vasil'ev
A V
AV
Bogdanova
S N
SN
Pogozheva
A V
AV
Varsanovich
E A
EA
Abakumov
A S
AS
D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000201:enzymology*; D003327:Coronary Disease / Q000097:blood / Q000178:diet therapy*; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000201:enzymology*; D008055:Lipids / Q000097:blood; D008066:Lipolysis; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D008875:Middle Aged
D015525:Fatty Acids, Omega-3; D008055:Lipids
Vliianie polinenasyshchennykh zhirnykh kislot semeĭstva omega-3 v sostave protivoateroskleroticheskoĭ diety na aktivnost' lizosomal'nykh lipoliticheskikh fermentov, mononuklearov i trombotsitov krovi u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.