DNA ploidy in primary fallopian-tube carcinoma using image cytometry.
Determination of DNA ploidy in 61 samples of primary Fallopian-tube carcinoma (FTC) by use of image cytometry is presented. Of these samples, 48 showed an aneuploid DNA content. Patients with euploid DNA content showed a median survival time of 33.8 months compared to 24.5 months for aneuploid cases. A high incidence of aneuploid tumors was consistently observed among all FIGO stages and in all groups of histologic grading. However, no correlation between ploidy and FIGO stage or histologic grading could be demonstrated. This observation could be regarded as a marker for the high aggressiveness of FTC which has been repeatedly described in the past.
Rosen
A C
AC
Department of Obstetrics and Gynecology, SMZ-Ost, Vienna, Austria.
Graf
A H
AH
Klein
M
M
Lahousen
M
M
Vavra
N
N
Reiner
A
A
Hacker
G W
GW
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004273:DNA, Neoplasm / Q000235:genetics*; D005185:Fallopian Tube Neoplasms / Q000235:genetics*; D005260:Female; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008875:Middle Aged; D009367:Neoplasm Staging; D011003:Ploidies; D012189:Retrospective Studies
D004273:DNA, Neoplasm