title: Peroxidation potential of rat thymus during development and involution.
abstract: The thymus of rats of ages between 1 and 7 months was homogenised and subjected to oxidative stress induced by iron salts. Lipid peroxidation, protein thiols and glutathione status were evaluated. The thymus of rats of 1 month of age exhibited lower susceptibility to the radical attack with respect to the thymus of rats between 3 and 7 months of age. This susceptibility was correlated with the content of polyunsaturated fatty acids and of lipophylic chain-breaking antioxidants.
authors.affiliation: Dipartimento di Biochemica, Università di Bologna, Italy.
authors.forename: M C
authors.initials: MC
authors.lastname: Galli
authors.forename: L
authors.initials: L
authors.lastname: Cabrini
authors.forename: F
authors.initials: F
authors.lastname: Caboni
authors.forename: M
authors.initials: M
authors.lastname: Cipollone
authors.forename: L
authors.initials: L
authors.lastname: Landi
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D005227:Fatty Acids / Q000378:metabolism; D005609:Free Radicals; D005978:Glutathione / Q000378:metabolism; D015227:Lipid Peroxidation; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013438:Sulfhydryl Compounds / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances; D013950:Thymus Gland / Q000254:growth & development / Q000378:metabolism*
chemical_list: D005227:Fatty Acids; D005609:Free Radicals; D013438:Sulfhydryl Compounds; D017392:Thiobarbituric Acid Reactive Substances; D005978:Glutathione