[Tumor necrosis factor in acute inflammatory diseases of the internal genitalia].
Blood serum cytotoxic activity of women with acute inflammatory diseases of the internal genitals was studied over the course of combined therapy, including immunomodulators, making use of target cells sensitive to the tumor necrosis factor (TNF). The levels of TNF activities varied within a wide range at the moment of the patients' admittance to hospital. TNF levels were high in the majority of patients or were increasing over the course of treatment. A low cytotoxic activity or its stable level over the course of treatment may be explained by a reduction of the immunocompetent cells functional activity.
Pogodin
O K
OK
Van'ko
L V
LV
Suleĭmanova
N S
NS
Samorodinova
L A
LA
Sukhikh
G T
GT
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D001681:Biological Assay / Q000379:methods; D003601:Cytotoxicity Tests, Immunologic; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D000292:Pelvic Inflammatory Disease / Q000097:blood* / Q000188:drug therapy / Q000276:immunology; D012008:Recurrence; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis* / Q000187:drug effects
D000276:Adjuvants, Immunologic; D014409:Tumor Necrosis Factor-alpha
Faktor nekroza opukholi pri ostrykh vospalitel'nykh zabolevaniiakh vnutrennikh genitaliĭ.