[Results of radiotherapy in 117 cases of carcinoma of pyriform sinuses].
A retrospective study was made of 117 cases of squamous cell carcinoma of the pyriform sinus treated with radiation therapy (RTX). Sixty-three patients underwent radical RTX (group I) and 54 patients received combined treatment (group II). Adjuvant chemotherapy (QTX) was applied in 36 patients (27 of group I, 9 of group II). Residual disease after treatment was observed in 35% (group I) and 4% (group II) (p < 0.001). The rates of local and/or regional recurrence were 46% and 38% respectively. Distant metastases were found in 6% (group I) and 20% (group II) (p < 0.05). The 5-year actuarial survival rates were 23% (group I) and 35% (group II). The group I patients who received QTX had better survival rates (41%) than those who did not (13%) (p < 0.05). The group II survival was not improved by QTX.
Ramos Fernández
J
J
Servicio de ORL, Hospital General Gregorio Marañón, Universidad Complutense, Madrid.
Avilés Mañoso
P
P
Martín Atienza
R
R
Lozano Barriuso
M A
MA
Fernández-Vega
M
M
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000401:mortality / Q000532:radiotherapy* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000628:therapy; D007830:Larynx / Q000528:radiation effects*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D015996:Survival Rate
Resultados del tratamiento radioterápico en 117 casos de carcinoma de seno piriforme.