The effect of dietary xylitol on dentin formation in ovariectomized rats.
Twenty-nine 3-month-old female Wistar rats were labeled by means of a single intraperitoneal tetracycline injection. Nineteen animals were subsequently ovariectomized, whereas a control group of 10 animals underwent sham operations. All the animals received the basal diet, and 10 of the ovariectomized animals were given an additional dietary xylitol supplementation (5%). Three months later the animals were killed by decapitation, and dentinal apposition on the molars was measured. The results indicate that supplementation of the diet with 5% xylitol had an attenuating effect on the enhanced dentin formation caused by ovariectomy, but the mechanism remains unsolved.
Svanberg
M
M
Institute of Dentistry, University of Oulu, Finland.
Hietala
E L
EL
Knuuttila
M
M
D000818:Animals; D001835:Body Weight; D003804:Dentin / Q000187:drug effects* / Q000502:physiology; D003810:Dentinogenesis / Q000187:drug effects*; D004032:Diet; D005260:Female; D005453:Fluorescence; D008963:Molar; D010052:Ovariectomy; D010053:Ovary / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D013752:Tetracycline; D014993:Xylitol / Q000008:administration & dosage / Q000494:pharmacology*
D013752:Tetracycline; D014993:Xylitol