Development of invasive adenocarcinoma following colectomy with ileoanal anastomosis for familial polyposis coli. Report of a case.
OBJECTIVE
Proctocolectomy with ileoanal anastomosis has gained increasing acceptance for the prophylactic treatment of patients with familial polyposis coli. Long-term surveillance of the ileal pouch and the pouch-anal anastomosis has not been emphasized despite concern regarding retained rectal mucosa following the procedure.


METHODS
A 34-year-old patient with a strong family history of familial polyposis coli was treated at 14 years of age by single-stage proctocolectomy with straight ileoanal anastomosis. Follow-up proctoscopic examinations revealed development of adenomatous changes at the ileoanal anastomosis.


RESULTS
This report presents a patient with familial polyposis coli who developed invasive adenocarcinoma at the ileoanal anastomosis 20 years after proctocolectomy with ileoanal anastomosis.


CONCLUSIONS
We stress the need for lifelong proctoscopic surveillance in patients with familial polyposis coli treated by proctocolectomy with ileoanal anastomosis.
Hoehner
J C
JC
Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City 52242.
Metcalf
A M
AM
D000230:Adenocarcinoma / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D011125:Adenomatous Polyposis Coli / Q000601:surgery*; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007078:Ileal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D007082:Ileum / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D016737:Proctocolectomy, Restorative; D013997:Time Factors