title: Value of routine pressure monitoring system changes after 72 hours of continuous use.
abstract: OBJECTIVE
  To assess the infection potential of not routinely changing invasive monitoring kits and associated plasticware.
  
  
  METHODS
  A prospective, observational study of microbiological contamination of a cohort of pressure monitoring infusion systems.
  
  
  METHODS
  Adult intensive care units in a university tertiary care center.
  
  
  METHODS
  Patients who had invasively monitored arterial, central venous, or pulmonary artery catheters in place for > or = 96 hrs without a change to the system were entered into the study.
  
  
  METHODS
  Fluid samples were obtained from the proximal stopcock of the monitoring kits every 24 hrs, beginning with a sample at 72 hrs and continuing until either the plasticware or catheter was changed or discontinued. Fluid samples were placed in tryptic soy broth and spread on blood agar plates within 24 hrs.
  
  
  RESULTS
  Of 451 intervals in which the system remained unviolated for > or = 96 hrs except for sampling, no positive cultures were found. Of the 333 monitoring kits/lines in the study, four cultures became positive within 48 hrs of a violation of the system (flush bag change). Positive cultures were obtained from two different patients, one patient having positive fluid cultures from arterial, central venous, and pulmonary arterial kits. This bacterial growth would not have been eliminated with routine system changes as it occurred within a 48-hr timeframe.
  
  
  CONCLUSIONS
  Invasive hemodynamic pressure monitoring systems including tubing and plasticware need not be changed routinely as these changes may cause a higher incidence of contamination due to increased violations of the systems.
authors.affiliation: Cardiopulmonary Services Department, University of Minnesota Hospital and Clinic, Minneapolis.
authors.forename: M K
authors.initials: MK
authors.lastname: O'Malley
authors.forename: F S
authors.initials: FS
authors.lastname: Rhame
authors.forename: F B
authors.initials: FB
authors.lastname: Cerra
authors.forename: R C
authors.initials: RC
authors.lastname: McComb
mesh_terms: D000328:Adult; D001795:Blood Pressure Determination / Q000009:adverse effects* / Q000295:instrumentation*; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000295:instrumentation; D002408:Catheters, Indwelling / Q000009:adverse effects; D016638:Critical Illness; D003428:Cross Infection / Q000209:etiology*; D006801:Humans; D007362:Intensive Care Units; D008991:Monitoring, Physiologic / Q000009:adverse effects / Q000295:instrumentation*; D011446:Prospective Studies; D013997:Time Factors