An end to Manicheism.
Although each vaccine has limitations, both OPV and E-IPV have made a considerable contribution to the effective control of polyomyelitis. In view of the complementary advantages of the two vaccines, more use of their association in a common schedule is quite justified. An association of OPV and E-IPV, in which the latter is combined with DTP, seems particularly advantageous immunologically, logistically, and economically. There are several alternative ways in which the two vaccines could be associated sequentially or simultaneously. In addition, each vaccine could be used as a booster for routine programs with the other vaccine.
Plotkin
S A
SA
Pasteur Mérieux Connaught, Marnes-la-Coquette, France.
D015721:Diphtheria-Tetanus-Pertussis Vaccine; D006291:Health Policy; D006801:Humans; D007115:Immunization Schedule; D007117:Immunization, Secondary; D011051:Poliomyelitis / Q000517:prevention & control*; D011054:Poliovirus Vaccine, Inactivated / Q000191:economics / Q000276:immunology; D011055:Poliovirus Vaccine, Oral / Q000191:economics / Q000276:immunology; D014611:Vaccination / Q000191:economics / Q000379:methods*; D017778:Vaccines, Combined
D015721:Diphtheria-Tetanus-Pertussis Vaccine; D011054:Poliovirus Vaccine, Inactivated; D011055:Poliovirus Vaccine, Oral; D017778:Vaccines, Combined