title: [Results of radiotherapy in 117 cases of carcinoma of pyriform sinuses].
abstract: A retrospective study was made of 117 cases of squamous cell carcinoma of the pyriform sinus treated with radiation therapy (RTX). Sixty-three patients underwent radical RTX (group I) and 54 patients received combined treatment (group II). Adjuvant chemotherapy (QTX) was applied in 36 patients (27 of group I, 9 of group II). Residual disease after treatment was observed in 35% (group I) and 4% (group II) (p < 0.001). The rates of local and/or regional recurrence were 46% and 38% respectively. Distant metastases were found in 6% (group I) and 20% (group II) (p < 0.05). The 5-year actuarial survival rates were 23% (group I) and 35% (group II). The group I patients who received QTX had better survival rates (41%) than those who did not (13%) (p < 0.05). The group II survival was not improved by QTX.
authors.affiliation: Servicio de ORL, Hospital General Gregorio Marañón, Universidad Complutense, Madrid.
authors.forename: J
authors.initials: J
authors.lastname: Ramos Fernández
authors.forename: P
authors.initials: P
authors.lastname: Avilés Mañoso
authors.forename: R
authors.initials: R
authors.lastname: Martín Atienza
authors.forename: M A
authors.initials: MA
authors.lastname: Lozano Barriuso
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Vega
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000401:mortality / Q000532:radiotherapy* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000628:therapy; D007830:Larynx / Q000528:radiation effects*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D015996:Survival Rate
vernacular_title: Resultados del tratamiento radioterápico en 117 casos de carcinoma de seno piriforme.