[Contractility and energy metabolism in human myocardium in normal state and in various stages of cardiac insufficiency].
Contractile function and metabolism of byoptates of human myocardium were investigated in the control group and at early stages of heart failure development. Support of the myocardial contractile function at the early stage of the heart failure is provided by intensive use of macroergic phosphates and their insufficient resynthesis. At the late stages of myocardial failure deterioration of the heart muscle relaxation was observed as a result of disturbances in transport of high-ergic phosphates to the sites of their utilization.
Shevchuk
V H
VH
Frantsuzova
S B
SB
Horchakova
N O
NO
Plyska
O I
OI
Babak
V V
VV
Arshynnykova
L L
LL
Lazoryshynets
V V
VV
Iakymovych
V V
VV
D002303:Cardiac Output, Low / Q000378:metabolism* / Q000503:physiopathology*; D003402:Creatine Kinase / Q000378:metabolism*; D004558:Electric Stimulation; D004734:Energy Metabolism; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000502:physiology; D009206:Myocardium / Q000378:metabolism*; D010725:Phosphocreatine / Q000378:metabolism*
D010725:Phosphocreatine; D003402:Creatine Kinase
Skorotlyva aktyvnist i enerhetychnyĭ obmin v miokardi liudyny v normi i na riznykh stadiiakh rozvytku sertsevoĭ nedostatnosti.