[Embryo reduction in multiple pregnancies. A French multicenter study].
OBJECTIVE
To study the outcome of multifetal pregnancy embryo reductions (MFPR) in France.


METHODS
A retrospective questionnaire multicenter survey was conducted in 11 French centers. 262 consecutive MFPR were collected. Miscarriage and prematurity rates were analyzed as a function of the starting number of embryos, the finishing number after MFPR, and the technique of MFPR.


RESULTS
There were 41 pregnancy losses before 24 weeks (16%), and 221 deliveries at 25 menstrual weeks or later (84%). Prematurity was significantly correlated to the finishing number of embryos following MFPR. However, even when a single embryo was left, there were 30% of premature deliveries.


CONCLUSIONS
MFPR decreases the risk of prematurity in multifetal pregnancies of high order, and this is best achieved when a single embryo is left.
Dommergues
M
M
Centre Hospitalo-Universitaire de Montpellier.
Aknin
J
J
Boulot
P
P
Nisand
I
I
Lewin
F
F
Oury
J F
JF
Herlicoviez
M
M
Dumez
Y
Y
Evans
M I
MI
D000028:Abortion, Induced / Q000379:methods; D000022:Abortion, Spontaneous / Q000209:etiology; D004622:Embryo, Mammalian; D005260:Female; D005602:France; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D012189:Retrospective Studies; D012307:Risk Factors; D014310:Triplets; D014427:Twins
Réduction embryonnaire dans les grossesses multiples. Une enquête multicentrique française. Pour le Club Francophone de Médecine Foetale.