[Pharmaceutical protection of brain in ischemia and reperfusion experiments].
The results of the use of medicamentous protection of the brain under conditions of modelled ischemia and reperfusion by means of KS-79 preparation are presented. In exclusion of blood flow through the carotid arteries for the period commensurate to that in the clinic, it was established that the use of KS-79 preparation possessing the anti-ischemic and antioxidant properties has pronounced cerebro-prospective action, preserves functional and structural integrity of the brain.
Klimenko
V N
VN
Belenichev
I F
IF
Bashkin
I N
IN
Kovalenko
S I
SI
Siniak
R S
RS
Vizir
V A
VA
Petrenko
A G
AG
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D002545:Brain Ischemia / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D002560:Cerebrovascular Circulation / Q000187:drug effects; D004285:Dogs; D005260:Female; D015227:Lipid Peroxidation; D008297:Male; D008954:Models, Biological; D010101:Oxygen Consumption; D015427:Reperfusion Injury / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*
Medikamentoznaia zashchita golovnogo mozga pri modelirovanii ishemii i reperfuzii.