Persistent hyperaminotransferasemia resolving after weight reduction in obese children.
Nine obese children were referred to our liver disease unit because of asymptomatic, long-standing (range, 4 to 49 months) hyperaminotransferasemia of unknown origin. Ultrasonography showed a "bright" liver in most patients. A hypocaloric diet was prescribed, and the hepatic abnormalities of the complaint patients showed a prompt and persistent improvement that paralleled the loss of excess weight.
Vajro
P
P
Department of Pediatrics, School of Medicine, University of Naples Federico II, Italy.
Fontanella
A
A
Perna
C
C
Orso
G
G
Tedesco
M
M
De Vincenzo
A
A
D000410:Alanine Transaminase / Q000097:blood*; D001219:Aspartate Aminotransferases / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D005234:Fatty Liver / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000097:blood* / Q000150:complications / Q000178:diet therapy; D015431:Weight Loss / Q000502:physiology*
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase