[Nude mouse interim host model for human parathyroid grafts].
Human parathyroid (PTG) tissues from cadaver (C-PTG), fetus (F-PTG) and PTG adenoma (A-PTG) were transplanted into the subcapsular space of Balb/C nude mouse kidney as interim host. The tissue structure and secretory function were examined 30, 60, 90, 120 and 150 days after operation. The results showed that PTG tissues from all three donors can retain their tissue structure and secretory function for more than 100 days in the nude mouse. The growth and function of PTG tissues from the three types of donors in the nude mice were compared.
Gao
Z
Z
PUMC Hospital, CAMS and PUMC, Beijing.
D000818:Animals; D016332:Fetal Tissue Transplantation; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D010280:Parathyroid Glands / Q000196:embryology / Q000637:transplantation*; D010282:Parathyroid Neoplasms; D013370:Subrenal Capsule Assay