title: [A case of drug induced pneumonitis caused by saiboku-To].
abstract: We report a case of drug induced pneumonitis caused by Saiboku-To. A 60-year-old woman was admitted to our hospital because of dry cough, fever and severe dyspnea after taking Saiboku-To. Blood gas analysis showed marked hypoxemia. Chest X-ray obtained on admission showed diffuse ground glass shadows in bilateral lung fields, and computed tomography showed diffuse interstitial shadows. Following steroid pulse therapy, clinical symptoms, hypoxemia and chest X-ray findings were ameliorated. Against medical advice, she took another Chinese medicine with ingredients similar to those of Saiboku-To. She complained of dry cough, fever and dyspnea and the chest X-ray again revealed diffuse ground glass shadows in both lung fields. Lymphocyte stimulation test against Saiboku-To and the patch test for Saiboku-To were positive. Therefore, we diagnosed this case as having pneumonitis due to Saiboku-To. This is first report of interstitial pneumonitis due to Saiboku-To.
authors.affiliation: Department of Internal Medicine, Toyama Prefecture Saisei Kai Takaoka Hospital, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Temaru
authors.forename: N
authors.initials: N
authors.lastname: Yamashita
authors.forename: S
authors.initials: S
authors.lastname: Matsui
authors.forename: T
authors.initials: T
authors.lastname: Ohta
authors.forename: A
authors.initials: A
authors.lastname: Kawasaki
authors.forename: M
authors.initials: M
authors.lastname: Kobayashi
mesh_terms: D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced*; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D020835:Medicine, Kampo; D008875:Middle Aged
chemical_list: D004365:Drugs, Chinese Herbal; C045086:saiboku-to