[Intra-arterial regional chemotherapy in the combined treatment of stage-III cancer of the stomach].
The report discusses a method of long-term catheterization of the celiac artery by lumbo-transaortal access. Intraarterial regional chemotherapy with 5-fluorouracil was administered to 56 cases of gastric cancer, stage III, before and after surgery. A significant drop in postoperative complication rate from 47.8 +/- 6% after surgery to 16.0 +/- 4% after combination treatment was recorded. During two years after operation, metastases and recurrences were registered in II out of 52 patients receiving intraarterial chemotherapy (21. +/- 5%), as compared with 34 out of 58 (58.6 +/- 6%) in controls without chemotherapy.
Zyrianov
B N
BN
Makarkin
N A
NA
Tikhonov
V I
VI
Tuzikov
S A
SA
D002408:Catheters, Indwelling; D002445:Celiac Artery; D017024:Chemotherapy, Adjuvant; D010478:Chemotherapy, Cancer, Regional Perfusion; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D007261:Infusions, Intra-Arterial; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
D005472:Fluorouracil
Vnutriarterial'naia regionarnaia khimioterapiia v kombinirovannom lechenii raka zheludka III stadii.