The future of intestinal pacing.
Pacing the human heart, first done in 1952, is commonly used today. Pacing the canine stomach and small intestine has also been accomplished and has been used to treat a variety of disease models, including dumping, the short bowel syndrome, gastroparesis, the Roux stasis syndrome, and tachygastria. In contrast, pacing the human stomach and small intestine has not progressed as far. Pacing of these organs in man has only been done for short intervals. Moreover, no clear-cut therapeutic applications have as yet emerged. Nonetheless, pacing holds promise as a future therapeutic modality for a variety of disorders of the human stomach and small bowel.
Cullen
J J
JJ
Department of Surgery, Mayo Graduate School of Medicine, Rochester, Minnesota.
Kelly
K A
KA
D000818:Animals; D004285:Dogs; D004377:Dumping Syndrome / Q000628:therapy; D004599:Electric Stimulation Therapy; D006801:Humans; D007421:Intestine, Small / Q000502:physiology*; D011183:Postoperative Complications / Q000628:therapy; D012778:Short Bowel Syndrome / Q000628:therapy; D013270:Stomach / Q000502:physiology*