Recoveries of post-tetanic twitch and train-of-four responses after administration of vecuronium with different inhalation anaesthetics and neuroleptanaesthesia.
We have studied recovery of post-tetanic twitch (PTT) and train-of-four (TOF) responses after administration of vecuronium in 100 patients under different inhalation anaesthetics and neuroleptanaesthesia. Patients were allocated randomly to five groups of 20 patients each to receive: neuroleptanaesthesia (droperidol and fentanyl), halothane, isoflurane, enflurane or sevoflurane (1 MAC in nitrous oxide and oxygen). The times from initial administration of vecuronium 0.2 mg kg-1 to the first appearances of T1, T2, T3 and T4 differed significantly between groups. However, the intervals to the first appearance of PTT1, PTT10 and PTT20 did not differ significantly between groups.
Saitoh
Y
Y
Department of Anaesthesiology and Critical Care Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
Toyooka
H
H
Amaha
K
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation; D004329:Droperidol; D004558:Electric Stimulation; D005260:Female; D005283:Fentanyl; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000187:drug effects; D009458:Neuroleptanalgesia; D009469:Neuromuscular Junction / Q000187:drug effects*; D013997:Time Factors; D014459:Ulnar Nerve / Q000502:physiology; D014673:Vecuronium Bromide
D014673:Vecuronium Bromide; D004329:Droperidol; D005283:Fentanyl