Feto-maternal plasma phenylalanine concentration gradient from 19 weeks gestation to term.
Plasma phenylalanine concentrations in fetal blood, obtained by cordocentesis, were compared with simultaneous peripheral venous plasma phenylalanine levels in mothers. The feto-maternal phenylalanine concentration ratio showed a gradual decrease from 19 weeks of gestation to term with an overall ratio of 1.35 +/- 0.42 (mean +/- S.D., n = 14).
Schoonheyt
W E
WE
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Clarke
J T
JT
Hanley
W B
WB
Johnson
J M
JM
Lehotay
D C
DC
D002852:Chromatography, Ion Exchange; D000013:Congenital Abnormalities / Q000097:blood / Q000000981:diagnostic imaging; D017218:Cordocentesis; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D010649:Phenylalanine / Q000097:blood*; D010661:Phenylketonurias / Q000097:blood; D011247:Pregnancy; D014463:Ultrasonography
D010649:Phenylalanine