Characteristics of paralytic shellfish poisoning toxins derived from short-necked clams (Tapes japonica) in Mikawa Bay.
A "red tide" bloom of Alexandrium tamarense occurred in Mikawa Bay in April 1991. In association with this, paralytic shellfish poisoning toxin was detected in short-necked clams by mouse bioassay. High performance liquid chromatography analysis demonstrated large quantities of the N-sulfocarbamoyl toxins, C1, and C2 (approximately 90% of the total toxins), whose latent potency was confirmed by treatment with boiling at low pH.
Okumura
M
M
Laboratory of Biology, Aichi Prefectural Institute of Public Health, Nagoya, Japan.
Yamada
S
S
Oshima
Y
Y
Ishikawa
N
N
D000818:Animals; D001681:Biological Assay; D049872:Bivalvia; D002851:Chromatography, High Pressure Liquid; D006863:Hydrogen-Ion Concentration; D007274:Injections, Intraperitoneal; D007564:Japan; D008297:Male; D008387:Marine Toxins / Q000032:analysis / Q000302:isolation & purification / Q000633:toxicity*; D051379:Mice; D010933:Plankton / Q000187:drug effects; D012530:Saxitoxin / Q000031:analogs & derivatives* / Q000032:analysis / Q000302:isolation & purification / Q000633:toxicity
D008387:Marine Toxins; D012530:Saxitoxin; C013007:gonyautoxins