title: [Changes of endogenous opioid peptides content in RPGL during acupuncture analgesia].
abstract: By push-pull perfusion technique and RIA of neuro-peptides, it was found that after 20 minutes' electroacupunture (EA), the release of LEK from the RPGL in the EA group was significantly higher than that in the control group (P < 0.05). The release of beta-EP from the RPGL in the EA group with higher efficacy was significantly higher than that in the control group (P < 0.05), but no significant changes were found in the EA group with lower efficacy. There was a positive correlation between the changes of release of LEK or beta-EP and the increase of pain threshold. The release of DynA1-13 tends to show a barely significant extent (P > 0.05). The results indicate that acupuncture analgesia is able to increase the release of LEK and beta-EP in the RPGL.
authors.affiliation: Department of Neurobiology, Shanghai Medical University.
authors.forename: L
authors.initials: L
authors.lastname: Zhou
authors.forename: J W
authors.initials: JW
authors.lastname: Jiang
authors.forename: G C
authors.initials: GC
authors.lastname: Wu
authors.forename: X D
authors.initials: XD
authors.lastname: Cao
mesh_terms: D015667:Acupuncture Analgesia; D000818:Animals; D004399:Dynorphins / Q000378:metabolism; D015671:Electroacupuncture; D004743:Enkephalin, Leucine / Q000378:metabolism*; D008297:Male; D008526:Medulla Oblongata / Q000378:metabolism*; D017288:Pain Threshold; D010446:Peptide Fragments / Q000378:metabolism; D051381:Rats; D012154:Reticular Formation / Q000378:metabolism; D001615:beta-Endorphin / Q000378:metabolism*
chemical_list: D010446:Peptide Fragments; D004743:Enkephalin, Leucine; D001615:beta-Endorphin; C026843:dynorphin (1-13); D004399:Dynorphins