[Complete response in a case of unresectable gastric cancer treated by combined chemoimmunotherapy of MMC, 5-FU and OK-432].
A 68-year-old female patient with unresectable advanced gastric cancer was treated by combined administration of MMC (10 mg/month), 5-FU (200 mg/day) and OK-432 (5KE/2 weeks). Two months after starting the treatment, there was a diminution in the serum CEA level. Six months later, the CEA had decreased to the normal level, primary and metastatic sites completely disappeared and no cancer cell was confirmed by endoscopic biopsy. The patient has survived for 33 months of a state of complete response.
Tsuji
Y
Y
First Dept. of Surgery, Kurume University School of Medicine.
Suematsu
T
T
Kawabata
S
S
Kodama
I
I
Koufuji
K
K
Aoyagi
K
K
Tanaka
T
T
Maruiwa
M
M
Ohta
J
J
Kumegawa
H
H
D000230:Adenocarcinoma / Q000628:therapy*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D016685:Mitomycin / Q000008:administration & dosage; D010844:Picibanil / Q000008:administration & dosage*; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000628:therapy*
D010844:Picibanil; D016685:Mitomycin; D005472:Fluorouracil