title: Telehygiene system for preventive chronopharmacology in space.
abstract: A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin-offs are the more effective the more of the chronome (time-structure) is resolved.
authors.affiliation: University of Minnesota, Minneapolis 55455.
authors.forename: F
authors.initials: F
authors.lastname: Halberg
authors.forename: G
authors.initials: G
authors.lastname: Cornélissen
authors.forename: C
authors.initials: C
authors.lastname: Bingham
authors.forename: F
authors.initials: F
authors.lastname: del Pozo
authors.forename: M T
authors.initials: MT
authors.lastname: Arredondo
authors.forename: K
authors.initials: K
authors.lastname: Otsuka
authors.forename: O
authors.initials: O
authors.lastname: Quadens
authors.forename: T
authors.initials: T
authors.lastname: Breus
authors.forename: S
authors.initials: S
authors.lastname: Rapoport
authors.forename: F
authors.initials: F
authors.lastname: Komarov
mesh_terms: D000337:Aerospace Medicine; D006801:Humans; D010507:Periodicity; D010600:Pharmacology; D012307:Risk Factors; D013026:Space Flight; D013686:Telemetry