title: Localization of the gene for ATP citrate lyase (ACLY) distal to gastrin(GAS) and proximal to D17S856 on chromosome 17q12-q21.
abstract: The gene encoding ATP-citrate lyase, designated ACLY, was mapped to human chromosome 17q12-q21 by PCR on a panel of human/rodent somatic cell hybrids and localized to 17q21.1 by PCR on a panel of radiation hybrids. The radiation hybrid panel indicates that the most likely position of ACLY on 17q21.1 is between gastrin (GAS) and D17S856 at a distance of 170-290 kb from the GAS locus.
authors.affiliation: University of Michigan, Department of Internal Medicine, Ann Arbor.
authors.forename: F J
authors.initials: FJ
authors.lastname: Couch
authors.forename: K J
authors.initials: KJ
authors.lastname: Abel
authors.forename: L C
authors.initials: LC
authors.lastname: Brody
authors.forename: M
authors.initials: M
authors.lastname: Boehnke
authors.forename: F S
authors.initials: FS
authors.lastname: Collins
authors.forename: B L
authors.initials: BL
authors.lastname: Weber
mesh_terms: D001275:ATP Citrate (pro-S)-Lyase / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D017931:DNA Primers; D005755:Gastrins / Q000235:genetics*; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D051381:Rats
chemical_list: D017931:DNA Primers; D005755:Gastrins; D005819:Genetic Markers; D001275:ATP Citrate (pro-S)-Lyase