[Food allergy in children. Diagnostic difficulties, doubts and digressions].
It is very difficult to diagnose an alimentary allergy especially because of: the difference among individuals in their physical, psychic and humoral reactions to the environment; weakness and variability of these reactions during the puberty; limited reliability in the results of certain kind of research (i.e. false positiveness and negativeness, discordance between laboratory results and the results of the challenge, neutralization of diagnostic antigenic extracts and/or the presence in these extracts of lectin, etc.); the bad compliance of some therapies and their restricted efficaciousness, particularly in the little children. Moreover: the superimposition of the clinical manifestations of alimentary allergy and pseudoallergy with those of allergy, the possibility of an association between the alimentary and the respiratory allergy, the acquisition on behalf of the allergic child of other kinds of allergy, false polyallergy, the allergy might change its seats and in consequence also its manifestations. The authors, apart a short account of the different diagnostic methods, lay stress on the challenge as the most reliable. They discuss upon the dose of a nourishment that can be given to the patient without risk, besides they suggest to take into account the type and the seriousness of the clinical manifestations in fixing this dose.
Paci
A
A
Clinica Pediatrica, Università degli Studi di Pisa.
Migliaccio
P
P
Crimaldi
G
G
Samueli
S
S
Orsolini
G
G
Palmieri
P
P
D002648:Child; D002675:Child, Preschool; D003888:Desensitization, Immunologic; D003937:Diagnosis, Differential; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D007159:Immunologic Tests
Allergia alimentare nel bambino. Difficoltà diagnostiche, dubbi, divagazioni.