title: The approach to nonresolving pneumonia.
abstract: Pneumonias that fail to resolve at the expected rate may reflect derangements in host defenses, inadequate or inappropriate antimicrobial therapy, highly virulent pathogens, or myriad noninfectious causes. In this article, noninfectious causes of pulmonary infiltrates mimicking community-acquired pneumonia are discussed. The salient clinical, radiographic, and histopathologic features of diverse immune-mediated syndromes are reviewed, and an approach to diagnosis and therapy of nonresolving pneumonias is presented.
authors.affiliation: Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor.
authors.forename: J B
authors.initials: JB
authors.lastname: Orens
authors.forename: R G
authors.initials: RG
authors.lastname: Sitrin
authors.forename: J P
authors.initials: JP
authors.lastname: Lynch
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D011014:Pneumonia / Q000139:chemically induced / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D017211:Treatment Failure