title: Effects of polycythaemia and haemodilution on circulation in neonates.
abstract: Haemodilution in nine neonates resulted in significant mean (SEM) decrease of packed cell volume (0.67 (0.01) to 0.55 (0.01)) and increases in cardiac output (250 (16) to 308 (25) ml/min/kg) and blood flow velocities of the internal carotid artery and the coeliac artery (+20%). However, red cell flows in the aorta, carotid and coeliac arteries did not change during haemodilution, thereby indicating that haemodilution did not improve oxygen transport.
authors.affiliation: Department of Neonatology Paediatrics, University of Heidelberg, Germany.
authors.forename: V H
authors.initials: VH
authors.lastname: Mandelbaum
authors.forename: C D
authors.initials: CD
authors.lastname: Guajardo
authors.forename: M
authors.initials: M
authors.lastname: Nelle
authors.forename: O
authors.initials: O
authors.lastname: Linderkamp
mesh_terms: D001783:Blood Flow Velocity; D002302:Cardiac Output; D002343:Carotid Artery, Internal / Q000503:physiopathology*; D002445:Celiac Artery / Q000503:physiopathology*; D006400:Hematocrit; D006438:Hemodilution; D006801:Humans; D007231:Infant, Newborn; D011086:Polycythemia / Q000503:physiopathology* / Q000628:therapy