title: Teniposide for meningeal carcinomatosis of small cell lung cancer.
abstract: A female patient with small cell lung cancer and extensive bone marrow metastases achieved a complete response after combination chemotherapy including etoposide. During maintenance therapy meningeal carcinomatosis was diagnosed. After intravenous administration of teniposide she improved dramatically during 3 months.
authors.affiliation: Department of Internal Medicine, University Hospital, Groningen, Netherlands.
authors.forename: W T
authors.initials: WT
authors.lastname: van der Graaf
authors.forename: H
authors.initials: H
authors.lastname: Haaxma-Reiche
authors.forename: J T
authors.initials: JT
authors.lastname: Burghouts
authors.forename: P E
authors.initials: PE
authors.lastname: Postmus
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D016190:Carboplatin / Q000008:administration & dosage; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000556:secondary* / Q000628:therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003907:Dexamethasone / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D007155:Immunologic Factors / Q000627:therapeutic use; D007278:Injections, Spinal; D007371:Interferon-gamma / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000628:therapy; D008577:Meningeal Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage; D013713:Teniposide / Q000008:administration & dosage / Q000627:therapeutic use*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D007155:Immunologic Factors; D014750:Vincristine; D005047:Etoposide; D009020:Morphine; D003907:Dexamethasone; D004317:Doxorubicin; D007371:Interferon-gamma; D003520:Cyclophosphamide; D013713:Teniposide; D016190:Carboplatin; D007069:Ifosfamide