[Effects of halothane on cerebral blood flow and its protective action in ischemia].
Halothane impact on cerebral blood flow, brain metabolism and its protective effect in ischemia have been assessed in 30 patients operated on for the occlusion of brachiocephalic arteries. The data obtained indicate that additional use of halothane in N2O:O2 anesthesia during reconstructive surgery on brachiocephalic arteries makes it possible to enhance collateral blood flow, increase retrograde pressure, and decrease O2 consumption by the brain, without considerable changes in systemic hemodynamics. In addition, the studies have shown that halothane decreases lipid peroxidation processes.
Seleznev
M N
MN
Guleshov
V A
VA
Grishchenko
M N
MN
Mil'chakov
V I
VI
Belov
Iu V
IuV
Gallinger
E Iu
EIu
Buniatian
A A
AA
D000328:Adult; D000769:Anesthesia, Inhalation; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002545:Brain Ischemia / Q000601:surgery*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D003097:Collateral Circulation / Q000187:drug effects; D004691:Endarterectomy; D006221:Halothane / Q000494:pharmacology*; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008875:Middle Aged; D008954:Models, Biological; D010101:Oxygen Consumption
D006221:Halothane
Vliianie ftorotana na mozgovoĭ krovotok i ego zashchitnoe deĭstvie pri ishemii.