[The effect of Capoten on the systemic and intracardiac hemodynamics in middle-aged and elderly hypertension patients].
Middle-aged and elderly patients with hypertonic disease were examined before and after three-week treatment with Capoten. In the first treatment resulted in significant fall arterial pressure and general peripheral resistance as well as in improvement of contractility. At the same time in the elderly reduced preload at the background of significantly decreased blood pressure led to restriction of Frank-Starling's mechanism and consequent deterioration of myocardial contractility.
Prikhod'ko
V Iu
VIu
D000368:Aged; D002216:Captopril / Q000494:pharmacology / Q000627:therapeutic use*; D002908:Chronic Disease; D004341:Drug Evaluation; D004452:Echocardiography / Q000187:drug effects; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged
D002216:Captopril
Vliianie kapotena na sistemnuiu i intrakardial'nuiu gemodinamiku u bol'nykh gipertonicheskoĭ bolezn'iu srednego i pozhilogo vozrasta.