Vibroacoustic stimulation in fetal sheep: effect on cerebral glucose utilization and behavioral state.
Behavioral state and cerebral glucose utilization were measured in six fetal sheep subjected to high intrauterine sound pressures created with a vibroacoustic stimulator pressed against the maternal abdomen. The signal consisted of a complex waveform that varied over time with a 50% duty cycle. An implanted hydrophone showed highest spectral levels between 3,000-16,000 Hz. The pulsed sound resulted in a significant loss of fetal rapid eye movement and non-rapid eye movement sleep. The stimulus also resulted in a disruption in the normally close relationship between these sleep states and cerebral glucose utilization rates in the brain as a whole and in its component parts.
Abrams
R M
RM
Department of Obstetrics and Gynecology, University of Florida, Gainesville 32610.
Peters
A J
AJ
Gerhardt
K J
KJ
Burchfield
D J
DJ
D000161:Acoustic Stimulation; D000818:Animals; D001345:Autoradiography; D001921:Brain / Q000196:embryology* / Q000378:metabolism; D005260:Female; D005333:Fetus / Q000502:physiology*; D005947:Glucose / Q000378:metabolism*; D011247:Pregnancy; D012756:Sheep; D012890:Sleep
D005947:Glucose