title: Treatment of the migraine attack.
abstract: Migraine is an episodic headache disorder that occurs with or without aura and is often accompanied by other symptoms. Treatment must address these associated symptoms as well as the headache, and it can involve either acute or preventive therapy alone or a combination of both. Acute therapy treats the individual attack; preventive therapy aims to reduce the frequency and severity of attacks. Drug choice requires careful consideration and depends on the character of the migraine attack. Acute drug therapy using sumatriptan, MK-462, 311C90, dihydroergotamine, nonsteroidal anti-inflammatory drugs, butorphanol, metoclopramide, and domperidone is discussed. Prophylactic drug therapy using valproate and fluoxetine is also discussed.
authors.affiliation: Department of Neurology, Germantown Hospital and Medical Center, Temple University School of Medicine, Philadelphia, PA 19144.
authors.forename: S D
authors.initials: SD
authors.lastname: Silberstein
mesh_terms: D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000188:drug therapy; D008881:Migraine Disorders / Q000188:drug therapy* / Q000517:prevention & control; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D017366:Serotonin Receptor Agonists; D014662:Vasoconstrictor Agents