title: [ICG-disappearance rate during sevoflurane- or neurolept anesthesia].
abstract: We evaluated the effect of sevoflurane or neuroleptanesthesia on ICG-disappearance rate in 22 patients undergoing elective extra-abdominal surgery. We divided the patients into three groups, i.e., SN-group (n = 8), SH-group (n = 8) and NLA-group (n = 6). Systolic arterial pressure (SAP) in the patients of SN-group or SH-group was maintained with sevoflurane at about 100% or 70% of the preoperative value respectively. There was no significant difference in SAP between SN-group and NLA-group. In SN-group and NLA-group, there was no significant difference in the ICG-disappearance rate between the values during anesthesia and those during preoperative period. In SH-group, however, it was significantly lower than the preoperative value. We conclude that, when normal systolic arterial pressure can be maintained, sevoflurane or neuroleptanesthesia has little effect on the liver function and hepatic blood flow. Sevoflurane anesthesia with 70% of preoperative SAP, however, may depress the liver function and hepatic blood flow.
authors.affiliation: Department of Anesthesiology and Resuscitology, Kochi Medical School, Nankoku.
authors.forename: J
authors.initials: J
authors.lastname: Aono
authors.forename: K
authors.initials: K
authors.lastname: Furuno
authors.forename: W
authors.initials: W
authors.lastname: Ueda
authors.forename: M
authors.initials: M
authors.lastname: Manabe
mesh_terms: D000368:Aged; D000769:Anesthesia, Inhalation; D004987:Ethers; D006801:Humans; D007208:Indocyanine Green / Q000493:pharmacokinetics*; D008099:Liver / Q000378:metabolism*; D008102:Liver Circulation; D008111:Liver Function Tests; D008738:Methyl Ethers; D008875:Middle Aged; D009458:Neuroleptanalgesia; D000077149:Sevoflurane
chemical_list: D004987:Ethers; D008738:Methyl Ethers; D000077149:Sevoflurane; D007208:Indocyanine Green