title: Principles of screening and congenital dislocation of the hip.
abstract: The call for screening for an increasing number of surgical diseases is becoming louder and more frequent. There is a general perception that screening is 'good' but it is important to consider the evidence carefully. There is one surgical disease that provides considerable experience of the process of screening over a period of 30 years and this is congenital dislocation of the hip (CDH). In retrospect, it is clear that screening for this disease has not been a total success. Although some specialised centres have achieved excellent results, in the country as a whole screening has been a failure. The reasons for this are analysed and emphasis is placed on the principles of screening which are briefly summarised. The results of various studies on screening and experiments on the basic functional anatomy of the neonatal hip are described. The initial results of our method of selective ultrasound screening appear to be encouraging and some evidence of a possible collagen abnormality in CDH is presented. As a general principle, however, it is suggested that strict randomised controlled trials should take place before national screening programmes are started.
authors.affiliation: Department of Children's Orthopaedic Surgery, School of Postgraduate Medical and Health Care Studies, Morriston Hospital, Swansea.
authors.forename: D A
authors.initials: DA
authors.lastname: Jones
mesh_terms: D003094:Collagen / Q000032:analysis; D004992:Ethics, Medical; D005260:Female; D006618:Hip Dislocation, Congenital / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000009:adverse effects / Q000379:methods*; D014463:Ultrasonography; D014470:Umbilical Cord / Q000737:chemistry
chemical_list: D003094:Collagen