The role of macrophage colony stimulating factor in the peritoneal fluid in infertile patients with endometriosis.
Macrophage colony stimulating factor (M-CSF) concentrations in the peritoneal fluid of 44 infertile patients were measured. The concentration of M-CSF was significantly higher in the patients with endometriosis than in those without endometriosis. There was no significant difference between the M-CSF concentration and stage of endometriosis classified by revised American Fertility Society (rAFS) classification in the 44 patients. However, in primary infertility patients with endometriosis there was a significant correlation between peritoneal M-CSF levels and rAFS points of endometriosis. We speculate that there is some relationship between the increased levels of M-CSF in the peritoneal cavity and the primary infertility associated with endometriosis especially progression of endometriosis.
Fukaya
T
T
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan.
Sugawara
J
J
Yoshida
H
H
Yajima
A
A
D001202:Ascitic Fluid / Q000378:metabolism*; D004715:Endometriosis / Q000150:complications / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications / Q000378:metabolism*; D016173:Macrophage Colony-Stimulating Factor / Q000378:metabolism*
D016173:Macrophage Colony-Stimulating Factor