title: Synovial-fluid D-lactic acid in bacterial and other acute joint effusions.
abstract: The use of D-lactic acid in differential diagnosis of bacterial arthritis was evaluated in a prospective study. The concentration of D-lactic acid was determined by the enzymatic UV-method in sixty-eight synovial fluids (SF) and in twenty four sera from adult patients with acute knee effusion. High concentrations of D-lactic acid (> 0.15 mmol/l) were measured most frequently in SF from bacterial arthritis, but also in individual culture-negative SF samples from patients with inflammatory culture-negative joint effusions with and without identified history of infections. Determination of SF D-lactic acid is not useful in differential diagnosis of bacterial arthritis.
authors.affiliation: Department of Surgery, University of Turku, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Kortekangas
authors.forename: O
authors.initials: O
authors.lastname: Peltola
authors.forename: A
authors.initials: A
authors.lastname: Toivanen
authors.forename: H T
authors.initials: HT
authors.lastname: Aro
mesh_terms: D001170:Arthritis, Infectious / Q000097:blood; D003937:Diagnosis, Differential; D006801:Humans; D007773:Lactates / Q000032:analysis* / Q000097:blood; D019344:Lactic Acid; D011446:Prospective Studies; D013582:Synovial Fluid / Q000737:chemistry*
chemical_list: D007773:Lactates; D019344:Lactic Acid