title: Hyperammonemia induced in rats by inhalation anesthesia with ether.
abstract: Transient hyperammonemia was observed in rats after inhalation anesthesia with ether. The elevation of blood ammonia concentration induced by ether anesthesia was greatest in carbon tetrachloride injured and indomethacin-treated rats, but not observed in phenobarbital-treated rats. The results suggest interaction between ether metabolism and ammonia metabolism in the liver.
authors.affiliation: Third Department of Internal Medicine, Faculty of Medicine, Toyama, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Kuwabara
mesh_terms: D000641:Ammonia / Q000097:blood* / Q000378:metabolism; D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D000818:Animals; D002251:Carbon Tetrachloride / Q000494:pharmacology; D004986:Ether / Q000633:toxicity*; D007213:Indomethacin / Q000494:pharmacology; D008099:Liver / Q000378:metabolism; D008297:Male; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004986:Ether; D000641:Ammonia; D002251:Carbon Tetrachloride; D007213:Indomethacin; D010634:Phenobarbital