title: Effect of magnesium on the physiology of Staphylococcus aureus.
abstract: The role of magnesium (Mg2+) in the metabolism of Staphylococcus aureus was studied using a chemically defined medium. At least 0.01 mM Mg2+ was required for any growth of S. aureus. Increasing concentration of Mg2+ up to 1.6mM steadily increased the bacterial growth. Glucose utilisation and acid production were also influenced by Mg2+. Excessive cobalt (Co2+) and zinc (Zn2+) were inhibitory to S. aureus growth and Mg2+ could reverse the inhibitory effect.
authors.affiliation: Department of Microbiology, Kasturba Medical College, Mangalore, India.
authors.forename: K G
authors.initials: KG
authors.lastname: Bhat
authors.forename: K M
authors.initials: KM
authors.lastname: Joseph
authors.forename: P G
authors.initials: PG
authors.lastname: Shivananda
mesh_terms: D003035:Cobalt / Q000494:pharmacology; D005947:Glucose / Q000378:metabolism; D008274:Magnesium / Q000494:pharmacology*; D008828:Microbiological Techniques; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000502:physiology*; D015032:Zinc / Q000494:pharmacology
chemical_list: D003035:Cobalt; D008274:Magnesium; D005947:Glucose; D015032:Zinc