title: [The efficacy of Ligenten gel in the prevention and treatment of infectious-inflammatory diseases of the urogenital organs].
abstract: A new therapeutic in the form of a gel named ligenten was studied. The gel active components are lidocain, gentamicin and ethonium. Ligenten was shown to have a marked local anesthetic action when administered transurethrally. As a prophylactic agent the gel was highly active against the majority of the causative agents of renal infections due to cystoscopy, catheterization and bougienage of the urethra. Ligenten provided a sufficient anesthetic effect in transurethral operations but did not prevent superinfection due to the hospital strains. Marked antiinflammatory and reparative actions of the gel especially in the treatment of ulcerous cystitis were observed.
authors.forename: T S
authors.initials: TS
authors.lastname: Perepanova
authors.forename: A F
authors.initials: AF
authors.lastname: Darenkov
authors.forename: E Z
authors.initials: EZ
authors.lastname: Kagan
authors.forename: V P
authors.initials: VP
authors.lastname: Pozdniakova
authors.forename: N I
authors.initials: NI
authors.lastname: Sinitsina
authors.forename: T S
authors.initials: TS
authors.lastname: Kotliarova
authors.forename: E M
authors.initials: EM
authors.lastname: Kondrat'eva
authors.forename: L N
authors.initials: LN
authors.lastname: Lavrinova
authors.forename: N V
authors.initials: NV
authors.lastname: Grishkova
authors.forename: V N
authors.initials: VN
authors.lastname: Siniukhin
mesh_terms: D000328:Adult; D000368:Aged; D000779:Anesthetics, Local / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D001437:Bacteriuria / Q000382:microbiology; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D005782:Gels; D005839:Gentamicins / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D008012:Lidocaine / Q000493:pharmacokinetics / Q000627:therapeutic use*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D000644:Quaternary Ammonium Compounds / Q000493:pharmacokinetics / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000378:metabolism / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D000779:Anesthetics, Local; D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D005782:Gels; D005839:Gentamicins; C089167:Ligenten; D000644:Quaternary Ammonium Compounds; D008012:Lidocaine
vernacular_title: Effektivnost' gelia Ligentena pri profilaktike i lecheniia infektsionno-vospalitel'nykh zabolevaniĭ mochepolovykh organov.