Development of myelopathy before herpes zoster rash in a patient with AIDS.
We describe the case of a patient with AIDS who developed progressive myelopathy due to varicella-zoster virus 2 months before the appearance of skin lesions typical of herpes zoster. Varicella-zoster virus was isolated from his CSF. Therapy with acyclovir failed to control his neurological complications despite its in vitro efficacy against the isolates.
Gómez-Tortosa
E
E
Department of Neurology, Fundación Jimenez Díaz, Madrid, Spain.
Gadea
I
I
Gegúndez
M I
MI
Esteban
A
A
Rábano
J
J
Fernández-Guerrero
M L
ML
Soriano
F
F
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006562:Herpes Zoster / Q000150:complications*; D014645:Herpesvirus 3, Human / Q000302:isolation & purification; D006801:Humans; D008297:Male; D009187:Myelitis / Q000134:cerebrospinal fluid / Q000209:etiology* / Q000382:microbiology; D012867:Skin / Q000473:pathology