title: [Changes of plasma motilin concentration in pregnancy and early postpartum period].
abstract: Plasma motilin concentration were determined by radioimmunoaction from 180 women during pregnancy and early postpartum period as compared with 20 healthy non-pregnant women. The results showed that mean plasma motilin concentration (384.40 +/- 110.30 ng/L) was higher in the first trimester of pregnancy than that of healthy non-pregnant women (366.12 +/- 96.23 ng/L), however, this difference did not reach statistical significance (P > 0.05). The mean plasma motilin concentration (323.90 +/- 125.10 ng/L) was lower in the second trimester of pregnancy than in the first trimester of pregnancy (P < 0.05), while the mean plasma motilin concentration in the third trimester of pregnancy (121.04 +/- 27.00 ng/L) was significantly lower than in second (P < 0.01) and the mean plasma motilin concentration in 3-5 d after delivery (443.05 +/- 140.79 ng/L) reached an even higher value (P < 0.01). Our results suggests that pregnancy appears to have a profound inhibitory effect on plasma motilin and this may in part be responsible for the gastrointestinal hypomotility during pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Tangdu Hospital, Fourth Military Medical University, Xian.
authors.forename: X H
authors.initials: XH
authors.lastname: Qiu
authors.forename: M G
authors.initials: MG
authors.lastname: Yang
authors.forename: J J
authors.initials: JJ
authors.lastname: Peng
authors.forename: P
authors.initials: P
authors.lastname: Tong
authors.forename: Y X
authors.initials: YX
authors.lastname: Huang
authors.forename: C F
authors.initials: CF
authors.lastname: Xu
authors.forename: Q L
authors.initials: QL
authors.lastname: Wang
authors.forename: M N
authors.initials: MN
authors.lastname: Zhang
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009037:Motilin / Q000097:blood*; D049590:Postpartum Period / Q000097:blood*; D011247:Pregnancy / Q000097:blood*
chemical_list: D009037:Motilin