title: The psychophysiology of voluntary immunomodulation.
abstract: In twenty-two studies of intentional effects of humans to change immune measures, only four monitored psychophysiologic parameters. One study reported physiologic alterations associated with immune changes. In this current study we examined changes in pulse rate and peripheral temperature associated with intentional changes in neutrophil adherence. Subjects had blood, pulse and temperature recordings collected before and after either a rest condition (Group A), or a self-regulation exercise (Groups B and C) for two sessions. Group C had four prior training sessions before participating in the experimental sessions. This study found no association between psychophysiologic alterations and neutrophil changes. The control group (A) demonstrated no significant neutrophil changes but showed physiologic alterations, whereas, the experimental group (C) that showed increases in neutrophil adherence demonstrated no significant physiologic changes. It was speculated that intentional changes on neutrophil adherence and the pattern of the psychophysiologic measures were associated with and reflective of cognitive activity.
authors.affiliation: Case Western Reserve University, Department of Pediatrics, Cleveland, Ohio.
authors.forename: H
authors.initials: H
authors.lastname: Hall
authors.forename: L
authors.initials: L
authors.lastname: Minnes
authors.forename: K
authors.initials: K
authors.lastname: Olness
mesh_terms: D000293:Adolescent / Q000502:physiology; D000328:Adult; D001769:Blood / Q000276:immunology; D005260:Female; D006339:Heart Rate; D006801:Humans; D007092:Imagination; D007070:Immunoglobulin A / Q000276:immunology; D008297:Male; D015213:Neuroimmunomodulation; D009504:Neutrophils / Q000276:immunology; D012064:Relaxation Therapy; D012463:Saliva / Q000276:immunology; D013696:Temperature
chemical_list: D007070:Immunoglobulin A