title: [Severe contact dermatitis caused by Parfenac cream].
abstract: Bufexamac is an anti-inflammatory agent used as topical treatment of various pruritic diseases. Since it was put on the market, this product has been blamed for the occurrence of contact dermatitis (eczema, urticaria) and, rarely, severe toxicodermia. We report a case of severe contact dermatitis developed after application of bufexamac (Parfenac) cream. Patch-tests performed two months after the acute phase were positive (+ + +) for both Parfenac cream and bufexamac.
authors.affiliation: Service de Dermatologie, Hôpital du Bocage, Dijon.
authors.forename: E
authors.initials: E
authors.lastname: Collet
authors.forename: M
authors.initials: M
authors.lastname: Lacroix
authors.forename: C
authors.initials: C
authors.lastname: Boulitrop Morvan
authors.forename: S
authors.initials: S
authors.lastname: Dalac
authors.forename: J
authors.initials: J
authors.lastname: Sallin
authors.forename: D
authors.initials: D
authors.lastname: Lambert
mesh_terms: D002019:Bufexamac / Q000008:administration & dosage / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000209:etiology* / Q000473:pathology; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010328:Patch Tests
chemical_list: D002019:Bufexamac
vernacular_title: Dermite de contact grave à la crème Parfenac.