title: The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head.
abstract: Avian sarcoma virus 31 contains an oncogene that we have named qin. qin codes for a nuclear protein, Qin, that is a member of the HNF-3/fork head family of transcriptional regulators. Within this family Qin is particularly closely related to rat brain factor 1 (BF-1), a telencephalon-specific gene presumed to play an important role in the development of the mammalian brain.
authors.affiliation: Department of Microbiology, University of Southern California School of Medicine, Los Angeles 90033-1034.
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: P K
authors.initials: PK
authors.lastname: Vogt
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001358:Avian Sarcoma Viruses / Q000235:genetics*; D001483:Base Sequence; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D002472:Cell Transformation, Viral; D002645:Chickens; D003001:Cloning, Molecular; D015870:Gene Expression; D005801:Genes, Homeobox; D008969:Molecular Sequence Data; D005810:Multigene Family; D009687:Nuclear Proteins / Q000235:genetics*; D009857:Oncogenes; D012333:RNA, Messenger / Q000235:genetics; D016415:Sequence Alignment; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D009687:Nuclear Proteins; D012333:RNA, Messenger; D014157:Transcription Factors