[Effect of 131I incorporation on the status of the reproductive system in male rats and the dose-dependent effect].
Radioactive 131I was injected in single doses 9.25, 37, and 92.5 kBq to prepubertal (30-day-old) male rats. Iodine incorporation in doses 37 and 92.5 kBq resulted in some functional changes in the reproductive system of mature rats: blood testosterone level increased, its hypothalamic aromatization intensified, and biologically active LH level in the blood dropped. Incorporation of 9.25 kBq of 131I had no effect on male reproductive system. A possibility of direct injury to rat testicles by 131I incorporation is suggested.
Tarasenko
L V
LV
Varga
S V
SV
Demchenko
V N
VN
Bol'shova
E V
EV
Nosenko
N D
ND
Sinitsyn
P V
PV
Chaĭkovskaia
L V
LV
Reznikov
A G
AG
D000818:Animals; D004298:Dopamine / Q000378:metabolism; D004307:Dose-Response Relationship, Radiation; D005837:Genitalia, Male / Q000528:radiation effects*; D007031:Hypothalamus / Q000378:metabolism / Q000528:radiation effects; D007457:Iodine Radioisotopes / Q000008:administration & dosage*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D012741:Sexual Maturation / Q000502:physiology; D013737:Testis / Q000378:metabolism / Q000528:radiation effects; D013739:Testosterone / Q000097:blood; D013974:Thyroxine / Q000097:blood
D007457:Iodine Radioisotopes; D013739:Testosterone; D007986:Luteinizing Hormone; D013974:Thyroxine; D004298:Dopamine; D009638:Norepinephrine
Vliianie inkorporatsii 131I na sostoianie reproduktivnoĭ sistemy samtsov krys dozozavisimogo éffekta.