Differential pulse polarographic determination of nizatidine in pharmaceutical formulations.
A sensitive dp polarographic method was applied to the analytical determination of nizatidine, a new histamine H2-receptor antagonist. Determination was performed in Britton-Robinson buffer, at pH approximately equal to 3, ionic strength mu = 0.2. Linear dependence was achieved in a concentration range of 1.33 to 165.72 micrograms/ml for different sensitivities. The method proposed was applied to the determination of nizatidine in capsules and injections.
Kapetanović
V
V
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Belgrade, Yugoslavia.
Milovanović
L
L
Vladimirov
S
S
D002626:Chemistry, Pharmaceutical; D006863:Hydrogen-Ion Concentration; D016567:Nizatidine / Q000032:analysis*; D011048:Polarography / Q000379:methods*
D016567:Nizatidine