Intraventricular and subarachnoid hemorrhage resulting from necrotizing vasculitis of the choroid plexus in a patient with Churg-Strauss syndrome.
Neurologic symptoms are common in patients with the Churg-Strauss syndrome and often manifest as a peripheral neuropathy of the mononeuritis multiplex type secondary to vasculitis. Reports of central nervous system involvement is less frequent and ranges from psychiatric disturbances to cerebral hemorrhage. We report the first case of pathologically documented vasculitis involving the choroid plexus causing massive and fatal intraventricular and subarachnoid hemorrhages in a 47-year-old patient with Churg-Strauss syndrome.
Chang
Y
Y
Department of Pathology, Stanford University Medical Center, CA 94305.
Kargas
S A
SA
Goates
J J
JJ
Horoupian
D S
DS
D001929:Brain Edema / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology*; D002831:Choroid Plexus / Q000098:blood supply* / Q000473:pathology; D015267:Churg-Strauss Syndrome / Q000473:pathology*; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D009504:Neutrophils / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000473:pathology*; D013345:Subarachnoid Hemorrhage / Q000473:pathology*; D014057:Tomography, X-Ray Computed