Localized pleural mesothelioma with elevation of high molecular weight insulin-like growth factor II and hypoglycemia.
Recurrent hypoglycemia occurred in a 48-year-old woman with a localized pleural mesothelioma. During hypoglycemia, serum high molecular weight insulin-like growth factor II (IGF-II) was elevated. The tumor also contained a high level of high molecular weight IGF-II. We propose that the primary cause of the hypoglycemia in this patient was the high molecular weight IGF-II produced by the tumor.
Sakamoto
T
T
Division of Pulmonary Medicine, University of Tsukuba, Ibaraki, Japan.
Kaneshige
H
H
Takeshi
A
A
Tsushima
T
T
Hasegawa
S
S
D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000209:etiology*; D007335:Insulin-Like Growth Factor II / Q000032:analysis*; D008654:Mesothelioma / Q000097:blood / Q000150:complications* / Q000601:surgery; D008875:Middle Aged; D008970:Molecular Weight; D010997:Pleural Neoplasms / Q000097:blood / Q000150:complications* / Q000601:surgery; D012008:Recurrence
D007335:Insulin-Like Growth Factor II