[Detection and treatment of hyperprolactinemia in male infertility].
The role of prolactin in males has not been satisfactorily explained. It has been proved that hyperprolactinemia has a negative effect both on spermiogenesis and spermatogenesis. It is widely known that the secretion of the pituitary hormones is of a pulsating character and occurs in the diurnal rhythm. Therefore, in order to select a group of patients with hyperprolactinemia qualified for Bromocriptine treatment it was necessary to test them for prolactin. 3 morning tests were taken at 15 minute intervals. The selected male group was later treated with Bromocriptine, following the method of administration recommended by the producer. Next the level of prolactin in patients serum was again determined. It has been determined that a single prolactin test is sufficient to diagnose hyperprolactinemia. In most males 3 prolactin tests were always either pathologic or normal. Most of the selected hyperprolactinemia--affected males after Bromocriptine treatment displayed positive therapeutic effects. The level of prolactin has dropped considerably and the potency has increased. The improvement in the semen picture varied from patient to patient.
Rogoza
A
A
Kliniki Połoznictwa Instytutu Połoznictwa i Chorób Kobiecych Am, Gdańsku.
Mierzejewski
W
W
Puzio
M
M
D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use*; D002940:Circadian Rhythm; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D009845:Oligospermia / Q000188:drug therapy* / Q000209:etiology; D011388:Prolactin / Q000097:blood; D016896:Treatment Outcome
D001971:Bromocriptine; D011388:Prolactin
Wykrywanaie i leczenie hiperprolaktynemii w czynniku meskim.