Contact allergy to 8-methoxypsoralen.
A 36-year-old female patient was treated with PUVA for dyshidrotic eczema that had not shown sufficient response to topical therapy over the previous months. PUVA therapy caused acute aggravation of the eczema. Patch testing demonstrated Type IV sensitization to 8-methoxypsoralen in Meladinine solution.
Korffmacher
H
H
Department of Internal Medicine, Ruhr University Bochum, Germany.
Hartwig
R
R
Matthes
U
U
Dirschka
T
T
Albassam
A
A
Weindorf
N
N
Altmeyer
P
P
D000328:Adult; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D017484:Dermatitis, Phototoxic / Q000175:diagnosis / Q000209:etiology*; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D011146:Eczema, Dyshidrotic / Q000188:drug therapy; D005260:Female; D006229:Hand Dermatoses / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008730:Methoxsalen / Q000009:adverse effects* / Q000627:therapeutic use; D011701:PUVA Therapy; D010328:Patch Tests
D008730:Methoxsalen