Sarcomatoid carcinoma of the lung. A case with atypical carcinoid and rhabdomyosarcomatous components.
Sarcomatoid carcinomas of the lung are uncommon malignant biphasic tumors composed of carcinomatous and sarcomatous components. The carcinomatous component is usually a squamous carcinoma, and the sarcomatous component usually resembles a fibrosarcoma or a malignant fibrous histiocytoma. The presence of rhabdomyoblastic differentiation in such neoplasms is exceedingly rare, with only seven documented cases. This report describes a unique case of sarcomatoid carcinoma in a 52-year-old woman in whom the sarcomatous component of the tumor was a rhabdomyosarcoma and the carcinomatous component was an atypical carcinoid. The authors know of no previous report of a sarcomatoid carcinoma of the lung in which the carcinomatous component is a carcinoid.
Rainosek
D E
DE
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Ro
J Y
JY
Ordonez
N G
NG
Kulaga
A D
AD
Ayala
A G
AG
D002276:Carcinoid Tumor / Q000737:chemistry / Q000473:pathology; D002296:Carcinosarcoma / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D002864:Chromogranins / Q000032:analysis; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008175:Lung Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D008875:Middle Aged; D012208:Rhabdomyosarcoma / Q000737:chemistry / Q000473:pathology
D002864:Chromogranins