title: [Primary hemorrhagic spindle cell tumor of the lymph node with amianthoid structures. Case report and review of the literature].
abstract: An example of a benign haemorrhagic spindle cell tumour of the lymph node (synonym: intranodal myofibroblastoma) is presented, which was first described 5 years ago and has not as yet been documented in the German literature. This rare benign mesenchymal neoplasm of the lymph node occurs almost exclusively in the inguinal region. Diagnostic criteria include its composition of myofibroblastic cells (with immunoreactivity for vimentin and actin), which may show nuclear palisading, the presence of peripheral haemorrhage zones and the occurrence of characteristic amianthoid structures, which have the ultrastructural appearance of dense meshworks of collagen fibers. Knowledge of this tumour entity is important for differential diagnosis of primary and secondary malignant mesenchymal neoplasias of the lymph node.
authors.affiliation: Departement Pathologie, Universität Zürich.
authors.forename: B C
authors.initials: BC
authors.lastname: Padberg
authors.forename: H J
authors.initials: HJ
authors.lastname: Holzhausen
authors.forename: G
authors.initials: G
authors.lastname: Weinland
authors.forename: C
authors.initials: C
authors.lastname: August
authors.forename: S
authors.initials: S
authors.lastname: Schröder
mesh_terms: D008841:Actin Cytoskeleton / Q000648:ultrastructure; D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007264:Inguinal Canal; D008198:Lymph Nodes / Q000473:pathology*; D008854:Microscopy, Electron; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D009379:Neoplasms, Muscle Tissue / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D014746:Vimentin
vernacular_title: Primärer hämorrhagischer Spindelzelltumor des Lymphknotens mit Amianthoidstrukturen. Fallbericht und Literaturübersicht.