Enantiomer-enantiomer interaction on N-monodemethylation of diuretic in rat liver microsomes.
Nakano
M
M
Drug Metabolism & Disposition Division, Kanzakigawa Laboratory, Shionogi Research Laboratories.
Chikai
T
T
Matsubara
T
T
D000584:Amiloride / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D000818:Animals; D003640:Dealkylation; D004232:Diuretics / Q000493:pharmacokinetics*; D005260:Female; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013237:Stereoisomerism
D004232:Diuretics; D000584:Amiloride; C064515:2',4'-dichlorobenzamil amiloride