[Identification of the metabolites of T-018 in the urine in female rats].
In order to identify the metabolites of T-018 (alpha-iso-butyl-p-hydroxybenzyl alcohol) in vivo, T-018 labelled with deuterium and unlabelled T-018 were administered intragastrically to two female rats. Based on the results measured by gas chromatograph mass spectrometry (GC/MS), T-018 and its four metabolites were found in the urinary extracts of the rats.
Jiang
J
J
PUMC Hospital, CAMS and PUMC, Beijing.
D000818:Animals; D001592:Benzyl Alcohols / Q000378:metabolism*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D062385:Hydroxybenzoates / Q000652:urine*; D006993:Hypnotics and Sedatives / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D001592:Benzyl Alcohols; D062385:Hydroxybenzoates; D006993:Hypnotics and Sedatives; C072528:alpha-isobutyl-4-hydroxybenzyl alcohol