title: Prevalence of periodontal pathogens with varying metabolic control of diabetes mellitus.
abstract: The purpose of this study was to determine the prevalence of 5 periodontal pathogens in individuals with diabetes mellitus. Subjects (n = 107) 20-70 years of age with type 1 (n = 60) or 2 (n = 47) diabetes mellitus were studied for the occurrence of the periodontal pathogens A. actinomycetemcomitans, F. nucleatum, E. corrodens, P. gingivalis and P. intermedia. Subgingival plaque was sampled in each subject from a single site exhibiting the greatest inflammation. The evaluation of selected periodontal bacterial pathogens was based on an immunoassay utilizing bacterial specific monoclonal antibodies. 35% of the sites harbored P. gingivalis, 28% F. nucleatum and 21% E. corrodens. A. actinomycetemcomitans and P. intermedia were found in less than 10% of the sites. Subjects for whom the probing depth at the sampled site was > or = 4 mm were more often found to have detectable pathogens than those with a probing depth < or = 3 mm. Diabetic factors such as duration, type and metabolic control of the disease had no statistically significant effect on the prevalence of these bacteria.
authors.affiliation: Department of Periodontology, University of Oulu, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Tervonen
authors.forename: R C
authors.initials: RC
authors.lastname: Oliver
authors.forename: L F
authors.initials: LF
authors.lastname: Wolff
authors.forename: J
authors.initials: J
authors.lastname: Bereuter
authors.forename: L
authors.initials: L
authors.lastname: Anderson
authors.forename: D M
authors.initials: DM
authors.lastname: Aeppli
mesh_terms: D000328:Adult; D000368:Aged; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D016009:Chi-Square Distribution; D003773:Dental Plaque / Q000382:microbiology*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000378:metabolism / Q000382:microbiology; D016124:Eikenella corrodens / Q000302:isolation & purification; D016967:Fusobacterium nucleatum / Q000302:isolation & purification; D006442:Glycated Hemoglobin / Q000032:analysis; D006089:Gram-Negative Anaerobic Bacteria / Q000302:isolation & purification; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000382:microbiology*; D010518:Periodontitis / Q000382:microbiology* / Q000473:pathology; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D015995:Prevalence
chemical_list: D006442:Glycated Hemoglobin