Potentiation of host defense mechanism against infection by a cytokine inducer, an acyl-MDP derivative, MDP-Lys(L18) (romurtide) in mice and humans.
Azuma
I
I
Institute of Immunological Science, Hokkaido University, Sapporo, Japan.
Otani
T
T
D000119:Acetylmuramyl-Alanyl-Isoglutamine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000276:immunology; D016207:Cytokines / Q000187:drug effects; D004357:Drug Synergism; D006410:Hematopoiesis / Q000187:drug effects; D006801:Humans; D007239:Infections / Q000188:drug therapy* / Q000276:immunology; D007970:Leukopenia / Q000188:drug therapy / Q000209:etiology; D051379:Mice; D009181:Mycoses / Q000188:drug therapy / Q000276:immunology; D009369:Neoplasms / Q000150:complications; D014777:Virus Diseases / Q000188:drug therapy / Q000276:immunology
D000276:Adjuvants, Immunologic; D000900:Anti-Bacterial Agents; D016207:Cytokines; D000119:Acetylmuramyl-Alanyl-Isoglutamine; C036866:romurtide