title: [Histologic changes in ligated vascular stumps in abdominal hysterectomy with adnexal resection and during postoperative prevention of thromboembolism with standard heparin].
abstract: Histological changes of ligated vasa ovarica, uterina, vessels of plica lata, mesosalpinx etc. were studied on 30 women. Thrombus formation, damage of the vessel wall and endothelial cell was observed after 30 min. We resected the stumps during abdominal hysterectomy and adnexotomy; preoperative injection of standard heparin (LDH) was given. We examined 30 stumps of vasa uterina and the same number of vasa ovarica stumps. A typical complete occlusive thrombus developed near the ligature in arteries once and in 3 veins (mainly a red thrombus formation). In 10 art. uterina and ovarica and 12 veins we found evidence of parietal thrombus formation made up of platelets and in a few cases fibrin was present. Heparin reduced the thrombus formation to a minimum. The vascular and endothelial lesions produced a direct and rapid obliteration of the vascular lumen by proliferation of tissue fibroblasts and muscle cells. No bleeding occurred after demarcation of the distal stumps ends.
authors.forename: R
authors.initials: R
authors.lastname: Slunský
mesh_terms: D000290:Adnexa Uteri / Q000601:surgery*; D001808:Blood Vessels / Q000473:pathology; D005260:Female; D006488:Hemostasis, Surgical; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D008026:Ligation; D008875:Middle Aged; D010053:Ovary / Q000098:blood supply*; D011183:Postoperative Complications / Q000517:prevention & control*; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control*; D014599:Uterus / Q000098:blood supply*
chemical_list: D006493:Heparin
vernacular_title: Histologické zmĕny v podvázaných cévních pahýlech pri abdominální hysterektomii s odstranĕním adnex a pri preoperacní prevenci tromboembolie standardním heparinem.