Fludrocortisone induced heart failure in Addison's disease.
The first reported case of congestive cardiac failure in a child with Addison's disease secondary to fludrocortisone therapy is presented. A renal adaptation to compensate for chronic salt and water deprivation is suggested as a possible mechanism for the development of congestive cardiac failure in this patient.
Willis
F R
FR
Department of Diabetes and Endocrinology, Princess Margaret Hospital for Children, Perth, Australia.
Byrne
G C
GC
Jones
T W
TW
D000224:Addison Disease / Q000188:drug therapy*; D002648:Child; D005438:Fludrocortisone / Q000009:adverse effects*; D006333:Heart Failure / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male
D005438:Fludrocortisone