[Salazopyrine desensitization].
Salazopyrin is effective in the management of connective tissue diseases, it is safe and useful for long-term management. However, it's use may be complicated by a skin rash which may necessitate withdrawal of therapy. Four patients with connective tissue diseases were treated with salazopyrin in desensitisation doses, as management with full dosage had previously been followed by a skin rash. In two patients, we were able to achieve a daily dosage of 2 g salazopyrin, in one case therapy was continued with a lower dosage, and withdrawal of the drug proved necessary in one patient. Desensitisation of salazopyrin induced rash is an easy procedure and is, possible in most cases. It may be worthwhile for many patients.
Schydlowsky
P
P
Reumatologisk afdeling, Københavns Amts Sygehus i Glostrup.
D003240:Connective Tissue Diseases / Q000188:drug therapy* / Q000276:immunology; D003888:Desensitization, Immunologic; D005076:Exanthema / Q000139:chemically induced / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D012460:Sulfasalazine / Q000008:administration & dosage* / Q000009:adverse effects / Q000276:immunology
D012460:Sulfasalazine
Salazopyrin-desensibilisering.