Hormonal and immunologic methods in the diagnosis and treatment of patients with benign ovarian tumors and endometriotic cysts.
OBJECTIVE
To compare efficacy of various methods for characterizing endometriosis and benign ovarian tumors.


METHODS
Two parallel groups of patients, 54 with endometriotic ovarian cysts and 48 with benign tumors.


METHODS
Central clinic.


METHODS
Patients referred from all regions over a 5-year period.


METHODS
Estrogen Estrogen and progesterone receptor levels of endometrium and endometriotic foci, CA-125 concentration, and estradiol, progesterone, LH, and testosterone blood levels.


RESULTS
LH levels elevated during follicular phase in patients; estradiol levels reduced; receptor levels abnormal in endometriosis, but not in benign ovarian cysts.


CONCLUSIONS
Hormone therapy is adequate treatment for endometriotic cysts. CA-125 is not a reliable indicator for differential diagnosis.
Adamyan
L V
LV
All-Union Centre for Maternal and Child Health Care of the Ministry of Health, Moscow, USSR.
Fanchenko
N D
ND
Alexeyeva
M L
ML
Andreyeva YeN
Novikov YeA
Jahan
I
I
D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003613:Danazol / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004715:Endometriosis / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D004717:Endometrium / Q000737:chemistry; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008597:Menstrual Cycle / Q000378:metabolism; D009640:Norethindrone / Q000008:administration & dosage; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D010907:Pituitary Hormones / Q000097:blood; D011959:Receptors, Estradiol / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D013739:Testosterone / Q000097:blood
D015295:Antigens, Tumor-Associated, Carbohydrate; D012739:Gonadal Steroid Hormones; D010907:Pituitary Hormones; D011959:Receptors, Estradiol; D011980:Receptors, Progesterone; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D003613:Danazol; D009640:Norethindrone