title: Carotid artery resection for cancer of the head and neck.
abstract: OBJECTIVE
  To compare the morbidity and mortality associated with ligation and reconstruction of the carotid artery after resection.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  Tertiary referral center and Veterans Affairs medical center.
  
  
  METHODS
  Twenty consecutive patients who underwent carotid artery resection for metastatic squamous cell carcinoma between January 1985 and June 1992.
  
  
  RESULTS
  Seven (58%) of 12 patients with ligation suffered neurological sequelae compared with one (13%) of eight patients with interposition grafts (P < .05). Six of eight patients with neurological sequelae had delayed onset of complications. Local control of tumor was achieved in 14 (74%) of 19 patients overall. Median survival was 6.3 months, and the 1-year disease-free survival rate was 16% (three patients).
  
  
  CONCLUSIONS
  Carotid artery replacement is superior to ligation in avoiding the neurological complications of carotid artery resection. Carotid artery resection can provide local control of tumor but fails to achieve a high rate of disease-free survival.
authors.affiliation: Department of Otolaryngology, Wayne State University School of Medicine, Detroit, Mich.
authors.forename: R J
authors.initials: RJ
authors.lastname: Meleca
authors.forename: S C
authors.initials: SC
authors.lastname: Marks
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002340:Carotid Artery Diseases / Q000473:pathology / Q000601:surgery*; D002561:Cerebrovascular Disorders / Q000209:etiology; D005260:Female; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008026:Ligation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications; D015996:Survival Rate; D013997:Time Factors