title: Right ventricular outflow tract ventricular tachycardia: detection of previously unrecognized anatomic abnormalities using cine magnetic resonance imaging.
abstract: OBJECTIVE
  This study attempted to determine whether cine magnetic resonance imaging (MRI), because of its unique ability to image the right ventricle, detects abnormalities in patients with right ventricular outflow tract ventricular tachycardia.
  
  
  BACKGROUND
  Right ventricular outflow tract ventricular tachycardia occurs in the absence of apparent structural heart disease.
  
  
  METHODS
  We compared cine MRI scans in 22 patients with right ventricular outflow tract ventricular tachycardia, 16 subjects without structural heart disease and 44 patients with other cardiovascular diseases. Echocardiography was performed in 21 patients with ventricular tachycardia.
  
  
  RESULTS
  All 22 patients with ventricular tachycardia had normal left ventricular function and no evidence of coronary artery disease. Cine MRI revealed right ventricular structural and wall motion abnormalities more often in patients with ventricular tachycardia (21 [95%] of 22) than in normal subjects (2 [12.5%] of 16, p < 0.0001) or patients without arrhythmia (17 [39%] of 44, p < 0.0001). The abnormalities in patients with ventricular tachycardia (fixed focal wall thinning, excavation, decreased systolic thickening) were located in the right ventricular outflow tract, whereas those in patients without arrhythmia were confined to the free wall. Cine MRI demonstrated abnormalities in patients with ventricular tachycardia more often than did echocardiography (21 [95%] of 22 vs. 2 [9%] of 21, respectively, p < 0.0001).
  
  
  CONCLUSIONS
  Right ventricular outflow tract ventricular tachycardia was associated with focal structural and wall motion abnormalities of the right ventricular outflow tract that were detected more often by cine MRI than by other imaging modalities and were not present in patients without arrhythmia or in normal subjects.
authors.affiliation: Division of Cardiology, University Hospital of Cleveland, Case Western Reserve University, Ohio.
authors.forename: M D
authors.initials: MD
authors.lastname: Carlson
authors.forename: R D
authors.initials: RD
authors.lastname: White
authors.forename: R G
authors.initials: RG
authors.lastname: Trohman
authors.forename: L P
authors.initials: LP
authors.lastname: Adler
authors.forename: L A
authors.initials: LA
authors.lastname: Biblo
authors.forename: K A
authors.initials: KA
authors.lastname: Merkatz
authors.forename: A L
authors.initials: AL
authors.lastname: Waldo
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D011237:Predictive Value of Tests; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000000981:diagnostic imaging; D016278:Ventricular Function, Right