title: [Cytomegalovirus infection in pregnant women and perinatal infants].
abstract: Perinatal cytomegalovirus (CMV) infection was studied, using method of CMV-IgM ELISA, in 256 pregnant women at different periods and in the cord blood of 84 babies born by CMV positive mothers. Results showed that in 42 cases at early and midtrimester pregnancy, 17 were CMV-IgM positive with an infection rate of 40.48%. Among the 214 women at late pregnancy, 84 were positive (39.25%). There was a higher prevalence of perinatal morbidity, neonatal asphyxia, malformation, intrauterine death, and poor obstetrical outcome in the CMV positive mothers as compared with the CMV negative group (P < 0.01). This study showed that the presence of CMV-IgM indicated a recent or recurrent CMV infection during pregnancy and the babies should be carefully monitored.
authors.affiliation: Yanan Hospital, Kuming.
authors.forename: R M
authors.initials: RM
authors.lastname: Yang
authors.forename: C Y
authors.initials: CY
authors.lastname: Gu
authors.forename: T X
authors.initials: TX
authors.lastname: Li
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification; D003586:Cytomegalovirus Infections; D005260:Female; D005312:Fetal Blood / Q000382:microbiology; D005315:Fetal Diseases / Q000382:microbiology*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D011256:Pregnancy Outcome; D011897:Random Allocation
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M