In-vitro models of cancer invasion and metastasis: recent developments.
Cancer metastasis is a process involving a number of related steps. Methods to mimic these individual steps have been established over past years in order to understand the cellular and molecular mechanism of tumour invasion and metastasis and design strategies for treatment. This review summarizes these in-vitro models.
Jiang
W G
WG
University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, UK.
D000818:Animals; D006801:Humans; D008954:Models, Biological; D009361:Neoplasm Invasiveness / Q000473:pathology / Q000503:physiopathology; D009362:Neoplasm Metastasis / Q000473:pathology / Q000503:physiopathology; D014407:Tumor Cells, Cultured