title: [Metrodin HP: a new highly purified FSH].
abstract: A new form of Metrodin (highly purified) characterized by the absence of any urinary protein contaminants and by a high specific activity, has been recently obtained through additional immunoextraction and chromatographic procedures. The respect of its main physico-chemical characteristics and the very low LH activity justify that the pharmacokinetics and the clinical efficacy of this new form are identical to those of the classical Metrodin. In a clinical point of view, Metrodin HP combines the double advantage of an excellent local and general tolerance (without any allergic side effect) and of a subcutaneous route of injection which allows a self-administration by the patient.
authors.affiliation: Unité de médecine de la reproduction, Hôpital Jean-Verdier, Bondy.
authors.forename: J N
authors.initials: JN
authors.lastname: Hugues
mesh_terms: D002845:Chromatography; D002986:Clinical Trials as Topic; D005640:Follicle Stimulating Hormone / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology / Q000600:supply & distribution / Q000627:therapeutic use*; D006801:Humans; D007279:Injections, Subcutaneous
chemical_list: D005640:Follicle Stimulating Hormone
vernacular_title: Métrodine HP: une nouvelle FSH hautement purifiée.