title: Perilymph fistula: concept, diagnosis and management.
abstract: Perilymph fistula is caused by changes of cerebrospinal fluid pressure and/or middle ear pressure. For diagnosis, history taking is extremely important in regard to whether the occurrence of symptoms is related to physical exertion, such as straining, nose blowing, sneezing etc. A variety of symptoms are due to pathologic changes of the membranous labyrinth. Exploratory tympanotomy is needed to verify the occurrence of leakage. However, perilymph fistula cannot be excluded, even if leakage is not observed. Management consists of absolute rest and closure of the fistula. If dizziness or vertigo is intractable and long-lasting, destruction of vestibular function should be considered.
authors.affiliation: Department of Otolaryngology, Showa University, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Nomura
mesh_terms: D015170:Cerebrospinal Fluid Pressure / Q000502:physiology; D005402:Fistula / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D006801:Humans; D007759:Labyrinth Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D010498:Perilymph / Q000502:physiology; D013701:Temporal Bone / Q000473:pathology; D014722:Vestibule, Labyrinth / Q000473:pathology