title: [The rare metastasis of osteosarcoma of a long bone associated with von Recklinghausen's neurofibromatosis].
abstract: We report a case of femoral osteosarcoma with brain metastases in a female patient with longstanding von Recklinghausen disease. Osteosarcoma of a long bone has not yet, to our best knowledge, been reported in association with type I Neurofibromatosis. Central nervous system metastases occur very rarely in osteosarcoma.
authors.affiliation: Centro de Lisboa, Instituto Português de Oncologia Francisco Gentil, Clínica VII.
authors.forename: M M
authors.initials: MM
authors.lastname: Ferreira
authors.forename: H
authors.initials: H
authors.lastname: Mansinho
authors.forename: A
authors.initials: A
authors.lastname: Fernandes
authors.forename: F S
authors.initials: FS
authors.lastname: Pereira
authors.forename: J A
authors.initials: JA
authors.lastname: Assis e Santos
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000628:therapy; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D005266:Femoral Neoplasms / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D009456:Neurofibromatosis 1 / Q000175:diagnosis* / Q000628:therapy; D012516:Osteosarcoma / Q000175:diagnosis* / Q000556:secondary* / Q000628:therapy
vernacular_title: Metastatização rara de osteossarcoma de um osso longo associado a neurofibromatose de von Recklinghausen.