[The esophageal motor pattern and the acid exposure of the distal esophagus in patients with gastroesophageal reflux].
Low-compliance standard manometry and 24-hour ambulatory pH monitoring were performed in 42 patients with typical gastro-esophageal reflux (GER) symptoms in order to assess correlations between esophageal motility pattern and pH profile. Our results show: 1) 36% of GER patients had a normal esophageal acid exposure; 2) pH profile and manometric pattern did not differ in patients with mild esophagitis from those without esophagitis; 3) low esophageal sphincter pressure in GER patients was significantly lower than in control subjects, irrespective of acid exposure; 4) the main motility disorders in the distal esophagus of reflux patients was the increased simultaneous wave rate which seemed to affect both recumbent esophageal clearance and reflux time.
Pustorino
S
S
Cattedra di Gastroenterologia, Università, Messina.
Federico
G
G
Calipari
G
G
Martinez
P
P
Pizzimenti
C
C
Barbera
G
G
Salvia
M A
MA
Migliorato
D
D
Consolo
F
F
D000328:Adult; D000368:Aged; D016145:Endoscopy, Digestive System; D004942:Esophagitis, Peptic / Q000503:physiopathology; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D005744:Gastric Acid / Q000502:physiology*; D005745:Gastric Acidity Determination / Q000295:instrumentation; D005764:Gastroesophageal Reflux / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D008875:Middle Aged; D010528:Peristalsis
Pattern motorio esofageo ed esposizione acida dell'esofago distale in pazienti con malattia da reflusso gastro-esofageo.