Non-Hodgkin's lymphoma in a patient with follicular thyroid cancer: the role of 99mTc-methoxy isobutyl isonitrile imaging.
In the post-surgical follow-up of a patient with follicular thyroid carcinoma, a palpable mass in the left supraclavicular region was highly indicative of metastatic disease. Technetium-99m methoxy isobutyl isonitrile (99mTc-MIBI) showed an increased but heterogeneous uptake within the lesion. Surprisingly, a different neoplastic disease was histologically demonstrated. Lymph node abnormalities due to non-Hodgkin's lymphoma rather than metastatic thyroid disease were demonstrated. In conclusion, non-Hodgkin's lymphoma may occur in patients with follicular thyroid carcinoma. This new lesion significantly concentrated 99mTc-MIBI. Thus, the results of 99mTc-MIBI imaging have to be carefully evaluated during the follow-up of patients with thyroid cancer.
Maurea
S
S
Department of Nuclear Medicine, National Cancer Institute, Naples, Italy.
Lastoria
S
S
Klain
M
M
Celentano
L
L
Salvatore
M
M
D018263:Adenocarcinoma, Follicular / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging*; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery
D017256:Technetium Tc 99m Sestamibi