title: [Karyometric analysis of pathologic changes in follicular cells of the thyroid gland].
abstract: Using cytometry it is shown, that distribution histograms of the values of follicular cell nuclear areas depend upon the nature of the thyroid disease. Dome-like distribution was observed in follicular and papillary cancer, while for follicular adenoma as well as for nodular colloid and diffuse toxic goiter or for autoimmune thyroiditis exponential-like dependence was typical. Distribution histograms under normal conditions had the form of a column. The phenomena observed can be used as an additional diagnostic criterion of malignant transformation of thyroid follicular cells.
authors.forename: V A
authors.initials: VA
authors.lastname: Kirillov
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Iushchenko
authors.forename: E P
authors.initials: EP
authors.lastname: Demidchik
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002467:Cell Nucleus / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007620:Karyometry; D008297:Male; D008875:Middle Aged; D013959:Thyroid Diseases / Q000473:pathology; D013961:Thyroid Gland / Q000648:ultrastructure*; D013964:Thyroid Neoplasms / Q000473:pathology
vernacular_title: Kariometricheskiĭ analiz patologicheskikh izmeneniĭ follikuliarnykh kletok shchitovidnoĭ zhelezy.