[Gliomatosis peritonei].
Gliomatosis peritonei (GP) is the implantation of glial tissue on the peritoneal surface in patients with solid ovarian teratoma. The average age at time of biopsy was 17.4 years in this study. The largest ovarian teratoma was 30cm in diameter with an average of 21.4cm. The tumor capsules were ruptured and adhered to the omentum in 5 cases. Peritoneal dissemination was detected in one patient at the second operation 10 months after the first one. It's believed that injury to the tumor capsule may have a role in peritoneal implantation. In general, regardless of the grade of the primary ovarian teratoma, the implanted peritoneal nodules consisted exclusively of GFAP and S-100 protein positive mature astroglia. The average length of follow up was 36.2 months. One patient with GP is alive and clinically healthy 8 years and 3 months post-operatively. The authors consider GP is a benign condition and associated with an improved prognosis for solid ovarian teratoma.
Tao
Y
Y
Department of Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou.
Hu
Y F
YF
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D005910:Glioma / Q000737:chemistry; D006801:Humans; D009361:Neoplasm Invasiveness; D010051:Ovarian Neoplasms / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000737:chemistry / Q000556:secondary*; D009418:S100 Proteins / Q000032:analysis; D013724:Teratoma / Q000473:pathology*
D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins