title: [The effect of the administration of an amino acid solution containing acetate on the calcium balance in surgical patients].
abstract: A frequent trouble in total parenteral nutrition is the occurrence of a negative calcium balance, due to reduction of calcium tubular reabsorption in acidosis. This condition could depend on acid metabolites raise, coming from degradation of nutritional amino acid mixtures. Authors have evaluated the effect of acetates addition to amino acid solutions on calcium balance. In fact the bicarbonate excess could reduce calcium urinary excretion. Thirty surgical patients have been treated. They were randomized according to acetates presence or absence in the administered solutions. In the acetate-treated group authors noted a raise in plasma bicarbonate and pH and a reduction in urinary calcium excretion. Adding acetates to amino acidic mixtures could reduce in total parenteral nutrition the risk of hypercalciuria and its related complications.
authors.affiliation: Dipartimento di Chirurgia, Università degli Studi di Pavia.
authors.forename: A
authors.initials: A
authors.lastname: Ferrari
authors.forename: L
authors.initials: L
authors.lastname: Vai
authors.forename: R
authors.initials: R
authors.lastname: Nucera
authors.forename: G
authors.initials: G
authors.lastname: Fornara
authors.forename: T
authors.initials: T
authors.lastname: Cebrelli
authors.forename: F
authors.initials: F
authors.lastname: Autelli
authors.forename: V
authors.initials: V
authors.lastname: Jemos
authors.forename: P
authors.initials: P
authors.lastname: Dionigi
authors.forename: A
authors.initials: A
authors.lastname: Zonta
mesh_terms: D000085:Acetates / Q000008:administration & dosage*; D000368:Aged; D000596:Amino Acids / Q000008:administration & dosage* / Q000032:analysis; D002118:Calcium / Q000032:analysis / Q000378:metabolism*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D010289:Parenteral Nutrition, Total; D011446:Prospective Studies; D013514:Surgical Procedures, Operative; D013997:Time Factors
chemical_list: D000085:Acetates; D000596:Amino Acids; D002118:Calcium
vernacular_title: Effetto della somministrazione di una soluzione di aminoacidi contenente acetato sul bilancio del calcio in pazienti chirurgici.