title: Interaction between pepsin and acid secretion during fundic perfusion in cat and rabbit.
abstract: 1. The effect of perfusion at pH 5.5 of a Heidenhain pouch on acid and pepsin secretion was studied in cats and rabbits. 2. In basal conditions, acid secretion was not modified by the perfusion while pepsin secretion was increased in both species. 3. After a meal, the perfusion did not modify the stimulation of acid secretion in cats nor the absence of secretions in rabbit. Stimulation of pepsin secretion was the same with or without perfusion in both species. 4. In rabbit, in contrast to cat, pepsin and acid secretions were independent during the meal-induced phase of gastric secretion.
authors.affiliation: INSERM U 45, Unité de Physio-Pathologie Digestive, Hôpital E. Herriot, Lyon, France.
authors.forename: M
authors.initials: M
authors.lastname: Descroix-Vagne
authors.forename: J P
authors.initials: JP
authors.lastname: Perret
authors.forename: M
authors.initials: M
authors.lastname: Daoud-el Baba
authors.forename: I
authors.initials: I
authors.lastname: Gros
authors.forename: H
authors.initials: H
authors.lastname: Rakotomalala
authors.forename: A
authors.initials: A
authors.lastname: Desvigne
authors.forename: G
authors.initials: G
authors.lastname: Jourdan
authors.forename: P
authors.initials: P
authors.lastname: Nicol
mesh_terms: D000818:Animals; D002415:Cats / Q000502:physiology*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005748:Gastric Fundus; D005753:Gastric Mucosa / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D010434:Pepsin A / Q000378:metabolism*; D010477:Perfusion; D011817:Rabbits / Q000502:physiology*
chemical_list: D010434:Pepsin A