title: Loss of flagellation in dnaA mutants of Escherichia coli.
abstract: A dnaA46 mutant of Escherichia coli showed loss of motility at 37 degrees C, a permissive temperature for cell growth of this mutant. Other dnaA mutations near the middle of the gene also caused an immotile phenotype. The amount of flagellin was much less in the dnaA46 mutant than in the wild-type control, as was the promoter activity. DnaA protein may play an important role in expression of the fliC gene.
authors.affiliation: Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Mizushima
authors.forename: A
authors.initials: A
authors.lastname: Tomura
authors.forename: T
authors.initials: T
authors.lastname: Shinpuku
authors.forename: T
authors.initials: T
authors.lastname: Miki
authors.forename: K
authors.initials: K
authors.lastname: Sekimizu
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D002455:Cell Division; D002465:Cell Movement; D004261:DNA Replication; D004268:DNA-Binding Proteins / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics / Q000254:growth & development / Q000502:physiology*; D005407:Flagella / Q000502:physiology*; D009154:Mutation; D013696:Temperature
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; C066312:DnaA protein, Bacteria