title: [Nalbuphine. Comparison of 2 therapeutic regimens for the control of postoperative pain].
abstract: The therapeutical efficiency and the undesirable effects of Nalbuphine administered to control postoperative pain were compared. Two groups of patients were studied: one group received 10 mg endovenously every 4 h during the first 12 h of the postoperative phase and every 6 h during the following 12 h while the other group received 20 mg with the same intervals. The following variants were evaluated: pain, systolic arterial tension, cardiac frequency, respiratory frequency and undesirable effects. After statistical analysis, a similarity in both groups was confirmed for pain, systolic arterial tension, cardiac frequency, while a significant difference was found in two of the undesirable effects: sedation and sweating. In conclusion, the 10 mg dose is as effective as that of 20 mg to control pain and has less unwanted effects.
authors.affiliation: Servicio de Clínica Médica, Sanatorio Delta, Rosario, Argentina.
authors.forename: D
authors.initials: D
authors.lastname: Bagilet
authors.forename: J
authors.initials: J
authors.lastname: Despósito
authors.forename: A
authors.initials: A
authors.lastname: Giovannoni
authors.forename: E
authors.initials: E
authors.lastname: Javkin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009266:Nalbuphine / Q000008:administration & dosage*; D010149:Postoperative Pain / Q000188:drug therapy*; D011446:Prospective Studies
chemical_list: D009266:Nalbuphine
vernacular_title: Nalbufina. Comparación de dos regímenes terapéuticos para el control del dolor postoperatorio.