title: Phosphorylation, allosteric effectors and inter-domain contacts in CAD; their role in regulation of early steps of pyrimidine biosynthesis.
authors.affiliation: Department of Biochemistry, University of Dundee, Scotland, U.K.
authors.forename: E A
authors.initials: EA
authors.lastname: Carrey
mesh_terms: D000494:Allosteric Regulation; D000818:Animals; D001221:Aspartate Carbamoyltransferase / Q000737:chemistry / Q000378:metabolism*; D001665:Binding Sites; D002223:Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) / Q000737:chemistry / Q000378:metabolism*; D004080:Dihydroorotase / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular; D015394:Molecular Structure; D009097:Multienzyme Complexes / Q000737:chemistry / Q000378:metabolism*; D010766:Phosphorylation; D011743:Pyrimidines / Q000096:biosynthesis*
chemical_list: C033626:CAD trifunctional enzyme; D009097:Multienzyme Complexes; D011743:Pyrimidines; D001221:Aspartate Carbamoyltransferase; D004080:Dihydroorotase; D002223:Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)