title: Management of breast cancer in the elderly.
abstract: The management of breast cancer in elderly women was analysed by a retrospective study of 150 women over 70 years old referred to our department between 1984 and 1988. 80 were T1-T2, 33 were T3 and 34 were T4. 107 were N0 and 43 were N1-N2. 16 women (11%) were in poor health, preventing conventional treatment. Treatment choice varied with age: 60% of the women aged 70-79 (group 1) and 23% of the oldest women (group 2) were treated conventionally. The use of surgery decreased with age and surgical procedures were conventional in only 85% of the group 1 women and in 56% of the group 2 women. Definitive radiation therapy was used more frequently in the oldest women, as was primary hormone therapy. Quality of follow-up also varied with age. Five-year survival rates were still high in both groups while relapses were frequent. Breast cancer was consequently a frequent cause of death. The increase in the proportion of elderly people with breast cancers over the next few years will require validated guidelines. Specific protocols and specific rules of management must be drawn up.
authors.affiliation: Département de Cancérologie, CHU Henri Mondor, Creteil, France.
authors.forename: L M
authors.initials: LM
authors.lastname: Martin
authors.forename: C
authors.initials: C
authors.lastname: le Pechoux
authors.forename: E
authors.initials: E
authors.lastname: Calitchi
authors.forename: Y
authors.initials: Y
authors.lastname: Otmezguine
authors.forename: F
authors.initials: F
authors.lastname: Feuilhade
authors.forename: B
authors.initials: B
authors.lastname: Brun
authors.forename: P
authors.initials: P
authors.lastname: Piedbois
authors.forename: J J
authors.initials: JJ
authors.lastname: Mazeron
authors.forename: M
authors.initials: M
authors.lastname: Julien
authors.forename: J P
authors.initials: JP
authors.lastname: le Bourgeois
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D012189:Retrospective Studies; D013629:Tamoxifen / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D013629:Tamoxifen