Acute ammonium dichromate poisoning.
We report the ingestion of ammonium dichromate by a child that resulted in multiple-organ-system failure and death. Exchange transfusion and hemodialysis were ineffective in removing significant amounts of chromium or causing sustained clinical improvement. We suggest that immediate, large doses of the reducing agent ascorbic acid would allow effective reduction of hexavalent chromium with less cellular toxicity.
Meert
K L
KL
Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit.
Ellis
J
J
Aronow
R
R
Perrin
E
E
D002840:Chromates / Q000506:poisoning*; D003131:Combined Modality Therapy; D005078:Exchange Transfusion, Whole Blood; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D008297:Male; D009102:Multiple Organ Failure / Q000139:chemically induced* / Q000628:therapy; D011041:Poisoning / Q000628:therapy; D006435:Renal Dialysis
D002840:Chromates; C013811:ammonium bichromate