title: [Studies on natural foci of tsutsugamushi disease of the autumn-winter type in Jiangsu].
abstract: Before 1986, tsutsugamushi disease was known only prevalent in south to Zhejiang Province in our country, belonged to the summer type and Leptotrombidium (L.) deliense was regarded as the main vector. In October 1986, the authors found this disease in Nanjing and carried out a series of studies in 1986-1992. The results were as follows: Tsutsugamushi disease was epidemic in Nanjing and north of Jiangsu (including: Dongtai, Haian, Rudong, Jinhu, Hanjiang, Jiangdu); belonged to the autumn-winter type; the main reservoir hosts were Apodemus agrarius, Rattus confucianus, R. norvegicus and Crocidura lasiura; the transmitting vector was L. (L.) scutellare; the pathogen of tsutsugamushi disease of the autumn-winter type-Rickettsia tsutsugamushi belonged to low-virulent strain, and could not easily be detected; after the inoculated mice were treated with diluted cyclophosphamide solution, 14 strains of R. tsutsugamushi have been isolated from rats, mites and patients; serological typing of their sera showed that they belonged to the Gilliam type; natural foci in Jiangsu could be divided into two types--flat land and hilly land.
authors.affiliation: Institute of Military Medicine, Nanjing Command, PLA.
authors.forename: H
authors.initials: H
authors.lastname: Guo
authors.forename: G
authors.initials: G
authors.lastname: Wu
authors.forename: M
authors.initials: M
authors.lastname: Xu
mesh_terms: D000818:Animals; D001096:Arachnid Vectors; D002681:China / Q000453:epidemiology; D004197:Disease Reservoirs; D006801:Humans; D008925:Mites / Q000382:microbiology*; D009115:Muridae / Q000382:microbiology; D012285:Orientia tsutsugamushi / Q000145:classification / Q000302:isolation & purification*; D051381:Rats; D012612:Scrub Typhus / Q000145:classification / Q000453:epidemiology*; D012621:Seasons