Atypical herpes simplex: a sign of toxoplasmosis activity in AIDS patients and the use of thalidomide.
Nowadays difficulties in detecting toxoplasmosis activity that usually is diagnosed in an advanced stage such as toxoplasmic encephalitis contributes to the poor prognosis of these patients. In four AIDS patients the increase of IgG, IgM and particularly IgA and atypical Herpes simplex onset were prior to the toxoplasmosis onset or recrudescence and mainly before neurologic symptoms onset. It was concluded that atypical Herpes simplex onset and immunoglobulin increase is an early sign of Toxoplasma activity.
Vosgerau
J C
JC
Department of Clinical Medicine, Universidade Estadual de Ponta Grossa, PR, Brazil.
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000188:drug therapy*; D000328:Adult; D006561:Herpes Simplex / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D014123:Toxoplasmosis / Q000150:complications / Q000188:drug therapy*