Multimodal evoked potentials in Binswanger's disease and Alzheimer's disease.
Short-latency somatosensory, brainstem auditory evoked potentials and event-related potentials were studied in 9 patients with Binswanger's disease (BD), 14 patients with Alzheimer's disease (AD) and 17 normal subjects. Patients with BD had a significantly longer interpeak latency between N13 and N20 (CCT), longer interpeak latency between waves I and V (I-V IPL) and longer P300 latency than normal subjects. In particular, CCT was significantly longer in patients with BD than in those with AD. In patients with AD, only I-V IPL and P300 latency were significantly longer in normal subjects. These results demonstrate an electrophysiological difference between BD and AD.
Tachibana
H
H
Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Kawabata
K
K
Takeda
M
M
Sugita
M
M
D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis*; D003704:Dementia / Q000175:diagnosis*; D016057:Evoked Potentials, Auditory, Brain Stem; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged