title: [Ophthalmologic manifestations in spinal cord diseases caused by HTLV-I virus. Clinical study of 30 cases].
abstract: We present the results of ophthalmologic examinations of a consecutive series of 30 patients with HTLV-I associated myelopathy. This is the first ophthalmologic prospective study reported outside the Japanese endemic area. Twenty-one of the patients (70%) had kerato-conjunctivitis sicca in addition to accessory salivary gland lymphocytary infiltration in 7. Two cases of uveo-papillitis, 1 case of cotton-wool spots and 3 cases of retinochoroidal degeneration were also observed. Moreover, an aliquot of the aqueous humour was collected from the anterior chamber in 5 patients and showed high titer of HTLV-I antibodies for the 2 patients with uveo-papillitis. We propose different hypotheses to explain the physiopathologic characteristics of these features.
authors.affiliation: Service d'Ophtalmologie, Centre Hospitalier Universitaire de Fort-de-France, Hôpital Pierre-Zobda-Quitman.
authors.forename: H
authors.initials: H
authors.lastname: Merle
authors.forename: D
authors.initials: D
authors.lastname: Smadja
authors.forename: O
authors.initials: O
authors.lastname: Bera
authors.forename: P
authors.initials: P
authors.lastname: Cabre
authors.forename: J C
authors.initials: JC
authors.lastname: Vernant
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005128:Eye Diseases / Q000209:etiology*; D005260:Female; D015490:HTLV-I Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008395:Martinique; D008875:Middle Aged; D010264:Paraplegia / Q000209:etiology*
vernacular_title: Manifestations ophtalmologiques au cours de la myélopathie due au virus HTLV-I. Etude clinique de 30 cas.