title: [Clinical effectiveness of pefloxacin (abaktal)in the treatment of inflammatory diseases of the kidneys, urinary tracts and genital organs].
abstract: Pefloxacin (Abaktal) was used in treatment of 83 patients: 14 patients with acute pyelonephritis, 5 patients with carbuncle of the kidney, 17 patients with postoperative acute pyelonephritis, 3 patients with urosepsis, 7 patients with acute prostatitis, 18 patients with chronic pyelonephritis in the phase of active inflammation, 9 patients with exacerbation of chronic prostatitis, 3 patients with acute cystitis, 2 patients with acute urethritis and 5 patients with epididymo-orchitis. Two dosage forms of pefloxacin were used i.e. tablets of 400 mg and ampoules of 5 ml containing 400 mg of the active substance. The treatment course amounted to 7-14 days. In the patients with inflammatory infectious diseases of the lower urinary tracts (cystitis and urethritis) the treatment course amounted up to 5 days. The results of the treatment with the ampoule solutions were good and satisfactory. With the use of the tablets the results were unsatisfactory in 3 patients (8.1 per cent). Satisfactory bacteriological efficacy of the treatment was stated in 89.5 per cent of the cases. The adverse reactions such as nausea, vomiting, diarrhea and skin eruption were recorded in 5 patients (6 per cent).
authors.forename: N A
authors.initials: NA
authors.lastname: Lopatkin
authors.forename: A F
authors.initials: AF
authors.lastname: Darenkov
authors.forename: I I
authors.initials: II
authors.lastname: Derevianko
authors.forename: T S
authors.initials: TS
authors.lastname: Perepanova
authors.forename: G A
authors.initials: GA
authors.lastname: Kotliarova
authors.forename: T A
authors.initials: TA
authors.lastname: Nosova
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D008297:Male; D052801:Male Urogenital Diseases / Q000188:drug therapy*; D008826:Microbial Sensitivity Tests; D009393:Nephritis / Q000188:drug therapy*; D015366:Pefloxacin / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D015366:Pefloxacin
vernacular_title: Klinicheskaia éffektivnost' pefloksatsina (abaktal*) v lechenii vospalitel'nykh zabolevaniĭ pochek, mochevyvodiashchikh puteĭ i polovykh organov.