title: Peptic ulcer disease: an update.
abstract: Peptic ulcers can develop when there is an imbalance between gastric acid secretion and gastroduodenal mucosal defense. Investigators are looking at the role of Helicobacter pylori in the development of peptic ulcer disease; eradication of the microorganism may reduce recurrence. Approved drug therapy includes H2-receptor antagonists, omeprazole, sucralfate, and antacids. Recommendations for treating and counseling patients are provided.
authors.affiliation: University of Michigan Medical Center, Ann Arbor.
authors.forename: R R
authors.initials: RR
authors.lastname: Berardi
authors.forename: V A
authors.initials: VA
authors.lastname: Dunn-Kucharski
mesh_terms: D000863:Antacids / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000009:adverse effects / Q000627:therapeutic use; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D010353:Patient Education as Topic; D010437:Peptic Ulcer / Q000188:drug therapy / Q000209:etiology
chemical_list: D000863:Antacids; D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists