title: [Effects of halothane on cerebral blood flow and its protective action in ischemia].
abstract: Halothane impact on cerebral blood flow, brain metabolism and its protective effect in ischemia have been assessed in 30 patients operated on for the occlusion of brachiocephalic arteries. The data obtained indicate that additional use of halothane in N2O:O2 anesthesia during reconstructive surgery on brachiocephalic arteries makes it possible to enhance collateral blood flow, increase retrograde pressure, and decrease O2 consumption by the brain, without considerable changes in systemic hemodynamics. In addition, the studies have shown that halothane decreases lipid peroxidation processes.
authors.forename: M N
authors.initials: MN
authors.lastname: Seleznev
authors.forename: V A
authors.initials: VA
authors.lastname: Guleshov
authors.forename: M N
authors.initials: MN
authors.lastname: Grishchenko
authors.forename: V I
authors.initials: VI
authors.lastname: Mil'chakov
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Belov
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Gallinger
authors.forename: A A
authors.initials: AA
authors.lastname: Buniatian
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002545:Brain Ischemia / Q000601:surgery*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D003097:Collateral Circulation / Q000187:drug effects; D004691:Endarterectomy; D006221:Halothane / Q000494:pharmacology*; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008875:Middle Aged; D008954:Models, Biological; D010101:Oxygen Consumption
chemical_list: D006221:Halothane
vernacular_title: Vliianie ftorotana na mozgovoĭ krovotok i ego zashchitnoe deĭstvie pri ishemii.