title: [Current aspects of infectious endocarditis. Apropos of 53 cases].
abstract: Fifty-three cases of infective endocarditis are reported: 10 definite, 33 probable, 10 possible. There were: 35 males, 18 females, mean age: 66 +/- 14 years. Twenty-three patients had a known valve involvement, 21 a recently diagnosed valve involvement, 9 a prosthetic valve. Fifty patients had fever, 43 had a regurgitating murmur, 28 weakness and weight-loss, 13 cutaneous lesions, 11 arthritis, 8 splenomegaly, 3 ocular lesions. The portal of entry was suspected or confirmed in 37 cases: intestinal in 12 cases, dental in 11 cases, cutaneous in 7 cases, urinary tract infection in 6 cases, upper respiratory tract infection in 1 case. The micro-organism was found in 45 cases: 10 oral streptococci, 12 D bovis streptococci, 6 enterococci, 5 aureus staphylococci, 3 coagulase-negative staphylococci, 2 Coxiella burnetii, 7 other bacterias. Blood-cultures were negative in 8 cases. Precordial echocardiography found vegetations in 27 native valves and 9 prosthetic alterations. Ten patients had neurologic complications, 27 cardiac complications, 8 acute renal failure. Nine patients needed cardiac surgery, 6 died. Our results, compared with those in the literature, showed older age, a higher frequency of digestive portal of entry and of D bovis streptococci, frequently associated with a colic tumour.
authors.affiliation: Service de Médecine Interne, Maladies Infectieuses, CHU, Hôpital Jean-Bernard, Poitiers.
authors.forename: J M
authors.initials: JM
authors.lastname: Gergaud
authors.forename: J P
authors.initials: JP
authors.lastname: Breux
authors.forename: G
authors.initials: G
authors.lastname: Grollier
authors.forename: P
authors.initials: P
authors.lastname: Roblot
authors.forename: B
authors.initials: B
authors.lastname: Becq-Giraudon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology; D013290:Streptococcal Infections / Q000175:diagnosis / Q000209:etiology
vernacular_title: Aspects actuels de l'endocardite infectieuse. A propos de 53 observations.