Fluorescent chemosensing of catechol and catecholamines in water.
It has been known for almost 35 years that catechol complexes reversibly to boronic acids. We observe that 2-anthrylboronic acid complexes catechol in water with Kd 330 microM and concomitant 20-fold reduction in fluorescence intensity. L-DOPA and dopamine behave similarly, suggesting a mechanism for the development of real-time sensing schemes.
Yoon
J
J
Department of Chemistry, Ohio State University, Columbus 43210.
Czarnik
A W
AW
D001665:Binding Sites; D001897:Boronic Acids / Q000737:chemistry; D002395:Catecholamines / Q000737:chemistry*; D002396:Catechols / Q000737:chemistry*; D004579:Electron Transport; D005453:Fluorescence; D010777:Photochemistry; D012996:Solutions; D014867:Water / Q000737:chemistry
D001897:Boronic Acids; D002395:Catecholamines; D002396:Catechols; D012996:Solutions; D014867:Water; C034221:catechol