[Effects of misoprostol, synthetic prostaglandin E1 analog, on secretion of TSH and thyroid hormones].
TSH stimulation tests were performed in 17 patients with gastric or duodenal ulcers. Before testing patients were given either 400 micrograms of misoprostol orally or placebo. TSH, T3, and T4 secretion after TRH was assessed. No significant effect of misoprostol on TSH, T3, and T4 secretion was found.
Jonderko
G
G
IV Katedry i Kliniki Chorób Wewnetrznych Sl. AM, Tychach.
Olak-Białoń
B
B
Kurkowski
L
L
Paździora
J
J
D000328:Adult; D004381:Duodenal Ulcer / Q000188:drug therapy; D006801:Humans; D008297:Male; D016595:Misoprostol / Q000494:pharmacology* / Q000627:therapeutic use; D013276:Stomach Ulcer / Q000188:drug therapy; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000378:metabolism*; D013974:Thyroxine / Q000378:metabolism*; D014284:Triiodothyronine / Q000378:metabolism
D014284:Triiodothyronine; D016595:Misoprostol; D013972:Thyrotropin; D013974:Thyroxine
Ocena wpływu misoprostolu, syntetycznego odpowiednika prostaglandyny E1, na wydzielanie TSH oraz hormonów tarczycy.