title: Partial duodenopancreatectomy with radical lymphadenectomy in patients with pancreatic and periampullary carcinomas: initial results.
abstract: Encouraged by the improved results of radical lymphadenectomy in patients with pancreatic carcinoma we designed and carried out a prospective study. Between Jan 88 and Jan 91, 17 patients (group A: cancer of the head of the pancreas, n = 5, periampullary cancer, n = 12) underwent a partial duodenopancreatectomy with radical lymphadenectomy, and 17 patients (group B: cancer of the head of the pancreas, n = 11), periampullary cancer, n = 6) underwent a partial duodenopancreatectomy without lymphadenectomy. Perioperative mortality was 17% (n = 3) in group A and 11.7% (n = 2) in group B. All three deaths in group A were due to erosion and hemorrhage of the completely dissected hepatic artery, and those in group B were due to pancreatitis and pneumonia, respectively. The cumulative 1-, 2- and 3-year survival rates for patients with pancreatic cancer who survived the operation were 50%, 50% and 50% for group A and 25%, 25% and 0% for group B. In patients with periampullary carcinoma 1-, 2-, and 3-year survival rates were all 47% for group A, and 100% for group B.
authors.affiliation: Dept. of Surgery, University of Hamburg, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Henne-Bruns
authors.forename: B
authors.initials: B
authors.lastname: Kremer
authors.forename: U
authors.initials: U
authors.lastname: Meyer-Pannwitt
authors.forename: I
authors.initials: I
authors.lastname: Vogel
authors.forename: S
authors.initials: S
authors.lastname: Schröder
mesh_terms: D014670:Ampulla of Vater; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000401:mortality / Q000601:surgery; D003138:Common Bile Duct Neoplasms / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000379:methods*; D011446:Prospective Studies; D015996:Survival Rate; D013997:Time Factors