Transmural myocardial infarction with sumatriptan.
For sumatriptan, tightness in the chest caused by an unknown mechanism has been reported in 3-5% of users. We describe a 47-year-old woman with an acute myocardial infarction after administration of sumatriptan 6 mg subcutaneously for cluster headache. The patient had no history of underlying ischaemic heart disease or Prinzmetal's angina. She recovered without complications.
Ottervanger
J P
JP
Netherlands Centre for Monitoring of Adverse Reactions to Drugs, Rijswijk.
Paalman
H J
HJ
Boxma
G L
GL
Stricker
B H
BH
D003027:Cluster Headache / Q000188:drug therapy; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007211:Indoles / Q000009:adverse effects* / Q000627:therapeutic use; D007279:Injections, Subcutaneous; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D009566:Nitrates / Q000627:therapeutic use; D017366:Serotonin Receptor Agonists / Q000009:adverse effects* / Q000627:therapeutic use; D013449:Sulfonamides / Q000009:adverse effects* / Q000627:therapeutic use; D018170:Sumatriptan
D007211:Indoles; D009566:Nitrates; D017366:Serotonin Receptor Agonists; D013449:Sulfonamides; D018170:Sumatriptan; D006493:Heparin