title: Three mitochondrial unassigned open reading frames of Podospora anserina represent remnants of a viral-type RNA polymerase gene.
abstract: The mitochondrial DNA of Podospora anserina is complex, consisting of a characteristic set of genes with a large number of introns and a substantial amount of sequence of unknown function and origin. In addition, as indicated by various types of reorganization, this genome is highly flexible. Here we report the identification of three unassigned mitochondrial open reading frames (ORF P', ORF Q', ORF 11) as remnants of a rearranged viral-type RNA polymerase gene. These ORFs are not transcribed and may be derived from the integration of a linear plasmid of the type recently identified in a mutant of P. anserina.
authors.affiliation: Department of Molecular Biology of Aging Processes, German Cancer Research Center, Heidelberg.
authors.forename: J
authors.initials: J
authors.lastname: Hermanns
authors.forename: H D
authors.initials: HD
authors.lastname: Osiewacz
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D004272:DNA, Mitochondrial / Q000235:genetics*; D012321:DNA-Directed RNA Polymerases / Q000235:genetics*; D005658:Fungi / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010957:Plasmids / Q000235:genetics; D011544:Pseudogenes; D016415:Sequence Alignment; D017385:Sequence Homology; D014764:Viral Proteins / Q000235:genetics*
chemical_list: D004272:DNA, Mitochondrial; D014764:Viral Proteins; D012321:DNA-Directed RNA Polymerases