[Determination of contrast sensitivity in patients with silicone oil tamponade].
The issue of whether silicone oil has a toxic effect on the retina is still being debated. In order to verify possible retinotoxic effects, the authors studied the variations of retinal function by means of computerized perimetry on patients who had undergone a vitreoretinal operation with injection of silicone oil in the vitreous cavity. Silicone oil remained in the eyes for a period of 120 days +/- 15.


METHODS
14 patients under treatment for vitreoretinal pathologies sparing the macula underwent five examinations (Macular Threshold Test of the Humphrey Field analyzer): two examination during the period silicone oil was in the vitreous cavity (30 days after injection and 10 days before removal) and three examinations after its removal (at 30, 90, and 180 days).


RESULTS
When the paired t-test and ANOVA test were applied to our results, there were no significant differences in the light-difference sensitivity.


CONCLUSIONS
These data do not indicate that silicone oil a retinotoxic effect (revealed by means of computerized perimetry) when it is removed within 4 months.
Uva
M G
MG
Institut für Augenheilkunde, Universität Catania.
Ott
J P
JP
Panta
G
G
Randazzo
D A
DA
Reibaldi
A
A
D000328:Adult; D015350:Contrast Sensitivity / Q000187:drug effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000601:surgery*; D012827:Silicone Oils / Q000008:administration & dosage / Q000009:adverse effects*; D058609:Visual Field Tests; D014821:Vitrectomy / Q000379:methods*
D012827:Silicone Oils
Bestimmung der Lichtunterschiedsempfindlichkeit bei Patienten mit Silikonölfüllung.