[The role of diet in the prevention and treatment of precancerous conditions in the risk groups].
The authors studied feasibility of using flavours, particularly, agent M-1 containing basic nutrients of antipromotor action in available form and fish oil containing fatty omega-3 acids as well as natural vitamin E for correction of homeostasis in patients with gastrointestinal precancer. 142 patients at risk to develop gastrointestinal cancer received diets for 6 months by 2-month cycles: M-1 daily in a dose 15-50 g, fish oil in a dose 10-30 ml. Control subjects did not receive the diets. 6 months after the treatment start the test subjects exhibited regression of the disease in 36.6% the cases versus 14.1% in the controls. It is concluded that the above dietetic scheme promotes correction of antioxidant insufficiency and stabilization of cellular membranes in patients with mucosal dysplasia.
Sotnikova
E N
EN
Drakina
L V
LV
Isaev
V A
VA
Ibragimov
V R
VR
Bikbov
T M
TM
Lisianskaia
I B
IB
Soloveva
N P
NP
Aleksandrova
L M
LM
D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D002462:Cell Membrane / Q000187:drug effects; D002617:Chemical Industry; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology / Q000627:therapeutic use; D005395:Fish Oils / Q000494:pharmacology / Q000627:therapeutic use*; D005420:Flavoproteins / Q000494:pharmacology / Q000627:therapeutic use*; D005527:Food, Fortified; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology; D005770:Gastrointestinal Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control*; D006801:Humans; D016273:Occupational Exposure; D011230:Precancerous Conditions / Q000628:therapy*; D012074:Remission Induction; D012307:Risk Factors; D016896:Treatment Outcome; D014810:Vitamin E / Q000494:pharmacology / Q000627:therapeutic use
D000975:Antioxidants; D015525:Fatty Acids, Omega-3; D005395:Fish Oils; D005420:Flavoproteins; D014810:Vitamin E
Rol pitaniia v profilaktike i korrektsii predopukholevykh sostoianiĭ v gruppakh riska.