title: Third component of complement serum levels in dogs with leishmaniasis.
abstract: Radial immunodiffusion was used to determine the concentration of the third component of complement (C3) in the serum of 51 adult dogs with leishmaniasis and, for comparative purposes, in a control group of 30 healthy dogs. Animals in both groups were of different age, sex and breed. The mean concentration in healthy dogs was 93.3 +/- 6.6 (mean +/- SD), and in sick dogs 131.4 +/- 7.1, both expressed as a percentage of a reference standard. Statistically significant differences (P < 0.0004) were found between serum C3 concentrations in leishmania-infected and control groups, but no significant difference was recorded between males and females in either group.
authors.affiliation: Dpto. Patología Clinica Veterinaria, Facultad de Veterinaria de Córdoba, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Lucena
authors.forename: J M
authors.initials: JM
authors.lastname: Molleda
authors.forename: P J
authors.initials: PJ
authors.lastname: Ginel
authors.forename: M
authors.initials: M
authors.lastname: Novales
authors.forename: E
authors.initials: E
authors.lastname: Martín
authors.forename: R
authors.initials: R
authors.lastname: López
mesh_terms: D000818:Animals; D003176:Complement C3 / Q000032:analysis*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs / Q000097:blood / Q000276:immunology*; D005260:Female; D005779:Immunodiffusion / Q000662:veterinary; D007896:Leishmaniasis / Q000276:immunology / Q000662:veterinary*; D008297:Male; D012016:Reference Values; D012727:Sex Characteristics
chemical_list: D003176:Complement C3