Normal and almost normal precocious variations in pubertal development premature pubarche and premature thelarche revisited.
Premature pubarche, premature thelarche and complete precocious puberty are usually simply normal phenomena occurring at an early age. This is not necessarily the case, however, and they may sometimes be harbingers of reproductive endocrine disturbances in adulthood. Consequently, girls with these complaints cannot be entirely reassured that they are of no consequence, and they should be followed to ascertain whether pubertal reproductive function is eventually normal.
Rosenfield
R L
RL
Department of Pediatrics, Pritzker School of Medicine, University of Chicago, IL 60637-1470.
D000728:Androgens / Q000096:biosynthesis; D001940:Breast / Q000254:growth & development; D002648:Child; D002675:Child, Preschool; D005260:Female; D006197:Hair / Q000254:growth & development; D006801:Humans; D011629:Puberty, Precocious / Q000503:physiopathology*; D011630:Pubic Bone
D000728:Androgens