[Defect bridging and augmentation of the mandible by transplantation of locally cultured bone in a porous matrix].
In the present study, 9 Göttingen Minipigs received one porous hydroxylapatite block each on the buccal cortex of their mandibles. Autogenous bone was gained inside these blocks by using a polylactic membrane covering for guided tissue regeneration. The blocks showed thorough penetration by bone tissue after 5 months and were transplanted as onlay grafts and for restoration of mandibular defects. The onlay grafts were fixed by titanium fixtures and miniplates respectively. Histologic examination 3 months after transplantation showed maintenance and remodelling of the transplanted bone inside the pores of the blocks in most specimens. There war a soft tissue free contact between the transplanted bone and the inserted fixtures and screws. Results indicate that autogenous bone may be gained inside a porous matrix of calcium phosphate and be transplanted for reconstruction of contour and discontinuity defects.
Schliephake
H
H
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie Medizinische Hochschule Hannover.
Neukam
F W
FW
Hutmacher
D
D
D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D016025:Bone Transplantation / Q000473:pathology / Q000502:physiology*; D017886:Durapatite; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D016348:Osseointegration / Q000502:physiology*; D019736:Prostheses and Implants; D013552:Swine; D013556:Swine, Miniature
D017886:Durapatite
Defektüberbrückung und Augmentation des Unterkiefers durch Transplantation von ortsständig angezüchtetem Knochen in einer porösen Matrix.