Acute spontaneous tumor lysis syndrome.
An 83-year-old woman with no previous history of malignancy was admitted to our institution with weakness and anemia and subsequently developed acute tumor lysis syndrome secondary to newly diagnosed Burkitt's leukemia/lymphoma. This syndrome has been previously described in patients with hematologic malignancies; however, its development has been related to the administration of chemotherapy, steroids, or radiotherapy. The spontaneous occurrence of tumor lysis syndrome has not been previously reported; however, Cohen et al. [Am J Med 58:486-491, 1980] report 8 of 37 patients with "clinically insignificant pretreatment derangements" of serum potassium, phosphate, and calcium.
Jasek
A M
AM
Department of Medicine, Abington Memorial Hospital, Pennsylvania.
Day
H J
HJ
D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D002051:Burkitt Lymphoma / Q000150:complications / Q000175:diagnosis; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D010710:Phosphates / Q000097:blood; D011188:Potassium / Q000097:blood; D015275:Tumor Lysis Syndrome / Q000097:blood / Q000175:diagnosis* / Q000209:etiology
D010710:Phosphates; D011188:Potassium; D002118:Calcium