Further bioactive cembranolide diterpenes from the gorgonian Eunicea succinea.
In our continuing comparative study of the diterpenoid content of the Caribbean gorgonian Eunicea succinea from different locations around Puerto Rico, three new cembranolide diterpenes, named 12,13-bisepieupalmerin acetate [5], 12-epi-eupalmerin acetate [6], and succinolide [7], were isolated from specimens collected off the east coast of Puerto Rico. The structure of each compound was deduced spectroscopically, and those of 5 and 7 were confirmed by chemical correlation with compounds of known structure.
Rodríguez
A D
AD
Department of Chemistry, University of Puerto Rico, Río Piedras 00931-3346.
Dhasmana
H
H
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D003063:Cnidaria / Q000737:chemistry*; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D014407:Tumor Cells, Cultured / Q000187:drug effects* / Q000473:pathology
D000970:Antineoplastic Agents; D004224:Diterpenes