Mucin deposits in morphea and systemic scleroderma.
BACKGROUND
Though rarely reported, mucin deposition may be observed in scleroderma.


OBJECTIVE
To verify the frequency of significant amounts of mucin in the biopsy specimens.


METHODS
Biopsies from 20 patients with scleroderma were reviewed and stained to verify the presence of mucin.


RESULTS
Mucin deposits were found in all of the 20 specimens.


CONCLUSIONS
Mucin deposition is probably a constant feature in both morphea and systemic scleroderma. Its relevance in differential diagnosis between scleredema and scleroderma is debatable.
Rongioletti
F
F
Department of Dermatology, University of Genoa, Italy.
Gambini
C
C
Micalizzi
C
C
Pastorino
A
A
Rebora
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism*; D012594:Scleroderma, Localized / Q000378:metabolism* / Q000473:pathology; D012595:Scleroderma, Systemic / Q000378:metabolism* / Q000473:pathology; D012867:Skin / Q000378:metabolism* / Q000473:pathology
D009077:Mucins