[Effects of "moist burn ointment--mei bao" on production of IL-2 in burn rats and its clinical problems].
Since "Mei Bao" has been used in clinical treatment of burn wounds, there is a diversity of opinions concerning its effect. We carried out a series of experiments to observe its therapeutic effect, bacteriostatic property, and its effect on production of IL-2 in thermally injured rats. These results indicate that obvious infection occurred after its use on burn wounds and healing is delayed. Hyperplastic scars accompanying with deformity appeared after healing. The cost of treatment is high. There is no improvement in immune reaction, and no bacteriostatic property is observed.
Yan
R
R
Department of Burn Surgery, Beijing Ji Shui Tan Hospital.
Zhu
M
M
Zhong
J
J
D000293:Adolescent; D000328:Adult; D000818:Animals; D000891:Anti-Infective Agents, Local / Q000009:adverse effects* / Q000494:pharmacology; D002056:Burns / Q000188:drug therapy* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009824:Ointments; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D014946:Wound Infection / Q000188:drug therapy*
D000891:Anti-Infective Agents, Local; D004365:Drugs, Chinese Herbal; D007376:Interleukin-2; D009824:Ointments