title: Limb-salvage surgery for treatment of sarcomas of the extremities.
abstract: The management of patients with sarcomas of the appendicular skeleton with limb-sparing surgery has become the standard of care. This is the result of advances in the understanding of the biology and staging of tumors, improvement in reconstructive techniques, and development of effective adjuvant chemotherapy and radiotherapy. A limb-sparing approach is applicable to virtually any bone lesion, whether low grade or high grade, and to all of the common primary soft-tissue sarcomas.
authors.affiliation: Department of Orthopedic Surgery, Saint Louis University Health Sciences Center, St. Louis, MO 63110.
authors.forename: D J
authors.initials: DJ
authors.lastname: McDonald
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation; D002648:Child; D005121:Extremities; D006801:Humans; D011183:Postoperative Complications; D016879:Salvage Therapy / Q000379:methods; D012509:Sarcoma / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000601:surgery*