[The diagnosis and prevention of parenterally transmitted viral infections].
The rate of the detection of the antibodies to HIV-1/2, HTLV-1, the markers of hepatitis B and C viruses and cytomegaloviruses in blood and plasma donors and persons with high risk of the infections was studied. A high percentage of the detection of the antibodies to hepatitis C virus (anti-HCV) was observed in the donors with increased levels of the serum enzymes, hematological patients, hemodialysis patients and drug addicts. A high rate of the indication of the HB virus markers was also observed in hematological patients and medical personnel of hematological and surgical clinics. At least 1 marker of HB virus was shown to be detected per 45 per cent of the reserve donors. The rate of the detection of anti-HCV in the donors of various regions ranged within 1-3 per cent in the Baltic countries, 2-5 per cent in Russia, 5-7 per cent in the Middle Asia and 8-12 per cent in Moldova. The data on the sensitivity and specificity of two commercial test systems for the detection of the antibodies to hepatitis C virus (Ortho, USA and Organon, Holland) were comparable.
Golosova
T V
TV
Somova
A V
AV
D000914:Antibodies, Viral / Q000097:blood; D001209:Asia, Central / Q000453:epidemiology; D001454:Baltic States / Q000453:epidemiology; D015415:Biomarkers / Q000097:blood; D001782:Blood Donors; D006801:Humans; D007159:Immunologic Tests; D008403:Mass Screening; D008966:Moldova / Q000453:epidemiology; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D012680:Sensitivity and Specificity; D016036:Seroepidemiologic Studies; D014777:Virus Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission
D000914:Antibodies, Viral; D015415:Biomarkers
Diagnostika i profilaktika virusnykh infektsiĭ s parenteral'noĭ peredacheĭ.