Principles for pathologic-anatomic diagnosis and classification of soft-tissue sarcomas.
Soft-tissue tumors are classified as frankly or potentially malignant, and as benign tumors and tumor-like lesions that can mimic soft-tissue sarcomas and other malignancies. Classification of soft-tissue sarcomas is based on knowledge or assumption of cell and tissue origin and differentiation. New principles and methods are used for the pathologic-anatomic diagnosis of these lesions. With increasing research on chromosomal aberrations and molecular biology, knowledge of the biology of soft-tissue sarcomas will grow, which in turn, will further revise current tumor classifications.
Angervall
L
L
Department of Pathology II, University of Goteborg, Sweden.
Kindblom
L G
LG
D001707:Biopsy, Needle; D003582:Cytogenetics; D004247:DNA / Q000032:analysis; D003937:Diagnosis, Differential; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007621:Karyotyping; D008854:Microscopy, Electron; D011003:Ploidies; D012150:Polymorphism, Restriction Fragment Length; D012509:Sarcoma / Q000145:classification* / Q000175:diagnosis / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000145:classification* / Q000175:diagnosis / Q000473:pathology
D004247:DNA