title: [Hydrodynamics of the eye in patients with neoplastic disease after general administration of cytostatic drugs].
abstract: The studies comprised 45 patients qualified for chemotherapy on account of neoplastic disease. The measurement of the intraocular pressure on the 1st, 2nd, 3rd and 4th day after administration of cytostatic drugs revealed its statistically significant lowering. During the observation no statistically significant differences were observed in the coefficient of outflow facility. It may be supposed that the decrease in intraocular pressure after general administration of cytostatic drugs is associated with the inhibition of secretion of intraocular fluid in ciliary body. For explanation of the hypotensive mechanism of cytostatic drugs animal experimental investigations are necessary.
authors.affiliation: Klinicznego Oddziału Okulistycznego, Wojskowego Szpitala Klinicznego, Bydgoszczy.
authors.forename: K
authors.initials: K
authors.lastname: Kacki
authors.forename: R
authors.initials: R
authors.lastname: Goś
authors.forename: J
authors.initials: J
authors.lastname: Tujakowski
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Hydrodynamika oka u osób z choroba nowotworowa po ogólnym podaniu cytostatyków.