title: Bone metastases in Wilms' tumor--report of three cases and review of literature.
abstract: Bone metastases are extremely rare in patients with classical Wilms' tumor (WT). We describe the clinical and radiologic features, treatment and outcome of three patients with WT (one with favorable histology and two with anaplasia) in whom bone metastases were detected at diagnosis or relapse. Bone metastases were documented by skeletal radiographs, computed tomography and/or bone scintigraphy. The patient with favorable histology WT had no evidence of pulmonary metastases and is now free of disease following aggressive chemotherapy and radiotherapy.
authors.affiliation: Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: S
authors.initials: S
authors.lastname: Gururangan
authors.forename: J A
authors.initials: JA
authors.lastname: Wilimas
authors.forename: B D
authors.initials: BD
authors.lastname: Fletcher
mesh_terms: D001707:Biopsy, Needle; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000000981:diagnostic imaging* / Q000556:secondary
chemical_list: D013669:Technetium Tc 99m Medronate