Serpins: the uncut version.
The structure of active antithrombin, the first active serpin to be solved, sheds new light on the conformational forms of this important class of inhibitor.
Goldsmith
E J
EJ
Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas 75235-9038.
Mottonen
J
J
D000991:Antithrombins / Q000737:chemistry; D001665:Binding Sites; D008958:Models, Molecular; D017395:Plasminogen Activator Inhibitor 1 / Q000737:chemistry; D011485:Protein Binding; D011487:Protein Conformation; D012697:Serine Endopeptidases / Q000378:metabolism; D015843:Serpins / Q000737:chemistry*; D000515:alpha 1-Antitrypsin / Q000737:chemistry
D000991:Antithrombins; D017395:Plasminogen Activator Inhibitor 1; D015843:Serpins; D000515:alpha 1-Antitrypsin; D012697:Serine Endopeptidases