Case report: localization of lipiodol-radioiodine in hepatic metastases from renal cell carcinoma.
Lipiodol, an iodinated derivative of poppyseed oil, is selectively retained in hepatocellular carcinoma and has been used as a vehicle to deliver localized doses of chemotherapeutic and radioactive agents to such tumours, thereby reducing the problems of external beam irradiation and the systemic toxicity of chemotherapy. We describe the first reported case where Lipiodol-targeted radiotherapy has been administered to a patient with secondary renal cell carcinoma in the liver. Localization was good and there were no complications. This case suggests that in future such patients may benefit from this therapy for unresectable lesions.
Stansby
G
G
University Department of Surgery, Royal Free Hospital and School of Medicine, London, UK.
Bhattacharya
S
S
Hilson
A J
AJ
Lane
D M
DM
Hobbs
K E
KE
D002292:Carcinoma, Renal Cell / Q000532:radiotherapy* / Q000556:secondary*; D004337:Drug Carriers; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D007459:Iodized Oil / Q000008:administration & dosage*; D008113:Liver Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D004337:Drug Carriers; D007457:Iodine Radioisotopes; D007459:Iodized Oil