title: Transfer in vivo of tuberculin hypersensitivity by sensitised lymphocytes.
abstract: An account is given of the experimental in vivo transfer of PPD-specific delayed hypersensitivity with a very small number of autologous lymphocytes pre-sensitised with PPD-specific transfer factor (TF). Transfer was assessed in 17 volunteers both in vivo by means of the Mantoux skin reaction, and in vitro by means of the leukocyte migration inhibition test, the lymphocyte locomotion test, and the leukocyte adherence inhibition test. Positivization of the tests suggests that TF triggers a reaction which expands the effect of hypersensitivity.
authors.affiliation: Chair of Medical Oncology, University of Turin, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Fazio
authors.forename: F
authors.initials: F
authors.lastname: Calabrese
authors.forename: S
authors.initials: S
authors.lastname: Giacomasso
authors.forename: G
authors.initials: G
authors.lastname: Meina
authors.forename: L
authors.initials: L
authors.lastname: Negri
authors.forename: V
authors.initials: V
authors.lastname: Mastromatteo
mesh_terms: D006801:Humans; D007957:Leukocyte Adherence Inhibition Test; D008214:Lymphocytes / Q000276:immunology*; D012882:Skin Tests; D014165:Transfer Factor / Q000494:pharmacology*; D014373:Tuberculin / Q000276:immunology*
chemical_list: D014165:Transfer Factor; D014373:Tuberculin