title: Localized pleural mesothelioma with elevation of high molecular weight insulin-like growth factor II and hypoglycemia.
abstract: Recurrent hypoglycemia occurred in a 48-year-old woman with a localized pleural mesothelioma. During hypoglycemia, serum high molecular weight insulin-like growth factor II (IGF-II) was elevated. The tumor also contained a high level of high molecular weight IGF-II. We propose that the primary cause of the hypoglycemia in this patient was the high molecular weight IGF-II produced by the tumor.
authors.affiliation: Division of Pulmonary Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sakamoto
authors.forename: H
authors.initials: H
authors.lastname: Kaneshige
authors.forename: A
authors.initials: A
authors.lastname: Takeshi
authors.forename: T
authors.initials: T
authors.lastname: Tsushima
authors.forename: S
authors.initials: S
authors.lastname: Hasegawa
mesh_terms: D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000209:etiology*; D007335:Insulin-Like Growth Factor II / Q000032:analysis*; D008654:Mesothelioma / Q000097:blood / Q000150:complications* / Q000601:surgery; D008875:Middle Aged; D008970:Molecular Weight; D010997:Pleural Neoplasms / Q000097:blood / Q000150:complications* / Q000601:surgery; D012008:Recurrence
chemical_list: D007335:Insulin-Like Growth Factor II