[Morphofunctional characteristics of the ovaries, thyroid gland and adrenal glands in experimental lead acetate poisoning].
Daily doses of 50 mg/kg of lead acetate injected into the laboratory animals induce morphologic changes in the parenchyma of ovaries, thyroid gland, adrenals and compromises neural mediating processes in paraventricular and supraoptic nuclei of hypothalamus. The observed morphologic changes are similar to those characteristic for intensive functioning. Prolonged exposure to lead acetate (daily dose 10 mg/kg) results in adaptation and compensation, which preserves the functional potential of the organs. The morphologic changes in the endocrine organs do not lead to significant hormonal changes.
Vylegzhanina
T A
TA
Kuznetsova
T E
TE
Maneeva
O A
OA
Novikov
I I
II
Ryzhkovskaia
E L
EL
D000311:Adrenal Glands / Q000187:drug effects* / Q000473:pathology; D000818:Animals; D005260:Female; D006168:Guinea Pigs; D007855:Lead Poisoning / Q000473:pathology*; D009942:Organometallic Compounds / Q000506:poisoning*; D010053:Ovary / Q000187:drug effects* / Q000473:pathology; D013961:Thyroid Gland / Q000187:drug effects* / Q000473:pathology
D009942:Organometallic Compounds; C008261:lead acetate
Morfofunktsional'naia kharakteristika iaichnikov, shchitovidnoĭ zhelezy i nadpochechnikov pri éksperimental'nom otravlenii uksusnokislym svintsom.