title: Evaluation of starch obtained from Ensete ventricosum as a binder and disintegrant for compressed tablets.
abstract: The binding and disintegrant properties of starch obtained from Ensete ventricosum Musaceae have been evaluated. The effect of the starch on the physical properties such as crushing strength, friability and disintegration time of tablets of chloroquine phosphate, dipyrone and paracetamol was compared with tablets prepared with potato starch. The results show that enset starch can be used both as a tablet binder and disintegrant and the indication is that enset starch has a better binding ability and less disintegrating power than potato starch.
authors.affiliation: School of Pharmacy, Addis Ababa University, Ethiopia.
authors.forename: T
authors.initials: T
authors.lastname: Gebre-Mariam
authors.forename: A S
authors.initials: AS
authors.lastname: Nikolayev
mesh_terms: D000082:Acetaminophen; D002626:Chemistry, Pharmaceutical; D002738:Chloroquine / Q000031:analogs & derivatives; D004177:Dipyrone; D005002:Ethiopia; D010936:Plant Extracts; D013213:Starch; D013607:Tablets
chemical_list: D010936:Plant Extracts; D013607:Tablets; D000082:Acetaminophen; D004177:Dipyrone; C023676:chloroquine diphosphate; D002738:Chloroquine; D013213:Starch