title: [Dietary folates--a timely review. Stability, physiological significance, bioavailability, analytical determination methods, effect of food handling].
abstract: Because of the unequal and, in some instances, low stability of different folate vitamers against extreme conditions the analytical determination of folate and the estimation of folate losses in food processing and preparation cause considerable difficulties. HPLC allows determination of the native folate derivative patterns. As the bioavailability of folates is influenced by a variety of factors and different methods were employed for assessing bioavailability there is a considerable inconsistency in the results of these studies. Folates labeled with radioactive or stable isotopes provide new approaches to metabolic and bioavailability studies.
authors.affiliation: Institut für Ernährungsphysiologie, Bundesforschungsanstalt für Ernährung, Karlsruhe.
authors.forename: C
authors.initials: C
authors.lastname: Pfeiffer
authors.forename: J F
authors.initials: JF
authors.lastname: Diehl
authors.forename: W
authors.initials: W
authors.lastname: Schwack
mesh_terms: D000818:Animals; D001682:Biological Availability; D002851:Chromatography, High Pressure Liquid; D004032:Diet; D004355:Drug Stability; D005492:Folic Acid / Q000008:administration & dosage* / Q000032:analysis / Q000737:chemistry / Q000493:pharmacokinetics; D005511:Food Handling; D006801:Humans
chemical_list: D005492:Folic Acid
vernacular_title: Nahrungsfolate--Eine aktuelle Ubersicht. Stabilität, Physiologische Bedeutung, Bioverfügbarkeit, analytische Bestimmungsmethoden, Einfluss der Lebensmittelbehandlung.