Malignant fibrous histiocytoma of the larynx.
Malignant fibrous histiocytoma of the upper respiratory tract is rare. We report a case of a glottic malignant fibrous histiocytoma in a 46-year-old man. Ultrastructural findings demonstrated that tumor cells were composed of fibroblast-like cells with abundant rough endoplasmic reticulum, histiocyte-like cells with numerous lysosomes and transitional cells with characteristics of both the fibroblast-like and histiocyte-like cells. Laryngeal microsurgery was performed as surgery and the patient has done well without recurrence to date (8 months after surgery).
Kuwabara
H
H
Department of Pathology, Kagawa Medical School, Japan.
Saito
K
K
Shibanushi
T
T
Kawahara
T
T
D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005347:Fibroblasts / Q000473:pathology; D005500:Follow-Up Studies; D015726:Giant Cells / Q000473:pathology; D005931:Glottis / Q000473:pathology*; D006644:Histiocytes / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008247:Lysosomes / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D000514:alpha 1-Antichymotrypsin / Q000032:analysis
D000514:alpha 1-Antichymotrypsin