[The use of perfluorocarbon emulsions for suppression of rejection reaction in kidney allotransplantation].
Successful solution of the problems of kidney transplantation is associated with further study of the pharmacological correction of the function of the kidneys. The article discusses the prospects of the use of perfluoran, a plasma substitute with a function of oxygen transport based on a perfluorocarbon emulsion, in the posttransplantation period for increasing the positive results of kidney transplantation. From the results of 24 dog experiments with allotransplantation of kidneys, a conclusion is drawn that the decrease of creatinine concentration in the blood with the use of perfluoran may be a consequence of the antiischemic properties of the emulsion. It is pointed out that thorough study of the condition of the parenchymatous organs in the body and the determination of the sequelae of the use of these blood substitutes are necessary.
Ilgiavishute
Ia S
IaS
Zhukauskas
G Iu
GIu
Dapshis
K L
KL
Onishchenko
N A
NA
D000818:Animals; D001802:Blood Substitutes / Q000627:therapeutic use*; D003404:Creatinine / Q000097:blood; D004285:Dogs; D004655:Emulsions; D005466:Fluorocarbons / Q000627:therapeutic use*; D006084:Graft Rejection / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D007165:Immunosuppression Therapy / Q000379:methods*; D016030:Kidney Transplantation / Q000276:immunology / Q000379:methods*; D008954:Models, Biological
D001802:Blood Substitutes; D004655:Emulsions; D005466:Fluorocarbons; C063334:perftoran; D003404:Creatinine
Ispolźovanie perftorouglerodnykh émulśiĭ dlia tormozheniia reaktsii ottorzheniia pri allotransplantatsii pochek.