title: Granulocytopenia secondary to acute infection with the human immunodeficiency virus.
abstract: Acute infection with the human immunodeficiency virus (HIV) is often characterised by a mononucleosis-like syndrome. We describe a patient who presented with the typical febrile syndrome associated with acute HIV infection, who also had significant granulocytopenia. Although granulocytopenia is relatively common in the later stages of HIV infection, it has only been described once before in the acute stage. The mechanism may be immune mediated, although data are limited. Clinicians should be aware of acute HIV infection as a possible cause of granulocytopenia.
authors.affiliation: University of Connecticut Health Center, Farmington 06030.
authors.forename: D J
authors.initials: DJ
authors.lastname: Skiest
authors.forename: M E
authors.initials: ME
authors.lastname: King
mesh_terms: D000208:Acute Disease; D000328:Adult; D000380:Agranulocytosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002969:Clavulanic Acids / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005334:Fever / Q000209:etiology; D005839:Gentamicins / Q000627:therapeutic use; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D015819:Substance Abuse, Intravenous / Q000150:complications; D013982:Ticarcillin / Q000627:therapeutic use
chemical_list: D002969:Clavulanic Acids; D005839:Gentamicins; C043215:ticarcillin-clavulanic acid; D013982:Ticarcillin