Effects of moderate amounts of emulsified dietary fat on postprandial lipemia and lipoproteins in normolipidemic adults.
Eight normolipidemic males ingested a meal containing either 42 g fat or 31 g fat in the form of emulsions (9.0 and 9.2 m2) and a fixed amount of retinyl palmitate. Fasting and postmeal blood samples were obtained for 7 h. Serum and chylomicron triglyceride responses were related to the amount of fat ingested and peaked after 2-3 h. The chylomicron retinyl palmitate response was lower (P < or = 0.05) with the 31-g fat supply. After the 42-g fat intake, but not after the 31-g fat intake, serum free cholesterol and phospholipids increased and esterified cholesterol decreased postprandially. Significantly different responses were observed after both meals for low-density-lipoprotein (LDL) free cholesterol, very-low-density-lipoprotein (VLDL) and LDL esterified cholesterol, and high-density-lipoprotein (HDL) phospholipids. These data show that ingesting 31 g instead of 42 g fat in a meal reduces postmeal lipoprotein variations and suggest that a threshold level of dietary fat should be overcome to promote significant postprandial changes in lipoprotein particles.
Dubois
C
C
Unité 130-INSERM (National Institute of Health and Medical Research), Marseille, France.
Armand
M
M
Azais-Braesco
V
V
Portugal
H
H
Pauli
A M
AM
Bernard
P M
PM
Latgé
C
C
Lafont
H
H
Borel
P
P
Lairon
D
D
D000328:Adult; D016588:Anticarcinogenic Agents / Q000097:blood; D002784:Cholesterol / Q000097:blood*; D002914:Chylomicrons / Q000097:blood; D004041:Dietary Fats / Q000008:administration & dosage / Q000494:pharmacology*; D004224:Diterpenes; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004435:Eating; D004655:Emulsions; D005215:Fasting / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D010743:Phospholipids / Q000097:blood; D000084562:Retinyl Esters; D014280:Triglycerides / Q000097:blood; D014801:Vitamin A / Q000031:analogs & derivatives / Q000097:blood
D016588:Anticarcinogenic Agents; D002914:Chylomicrons; D004041:Dietary Fats; D004224:Diterpenes; D004655:Emulsions; D007328:Insulin; D008055:Lipids; D008074:Lipoproteins; D010743:Phospholipids; D000084562:Retinyl Esters; D014280:Triglycerides; D014801:Vitamin A; C014794:retinol palmitate; D002784:Cholesterol