title: Tyrosine hydroxylase immunoreactivity in cerebellar Purkinje cells of the rat.
abstract: Employing tyrosine hydroxylase (TH) immunohistochemistry, we have revealed that TH immunoreactivity occurs in cerebellar Purkinje cells in the rat. These TH-immunoreactive Purkinje cells were distributed predominantly in the crus I & II ansiform lobules and the paraflocculus, and to a lesser extent in the I & X vermal lobules. Since Purkinje cells in such cerebellar regions displayed no immunoreactivity to dopamine-beta-hydroxylase, the TH-immunoreactive Purkinje cells identified in the present study might contain dopamine or L-DOPA.
authors.affiliation: Department of Anatomy and Cell Biology, University of Toronto, Ont., Canada.
authors.forename: M
authors.initials: M
authors.lastname: Takada
authors.forename: T
authors.initials: T
authors.lastname: Sugimoto
authors.forename: T
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000033:anatomy & histology / Q000201:enzymology*; D003712:Dendrites / Q000201:enzymology / Q000648:ultrastructure; D004299:Dopamine beta-Hydroxylase / Q000032:analysis; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008297:Male; D009412:Nerve Fibers / Q000201:enzymology / Q000648:ultrastructure; D009928:Organ Specificity; D011689:Purkinje Cells / Q000166:cytology / Q000201:enzymology*; D051381:Rats; D017208:Rats, Wistar; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis*
chemical_list: D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase