title: [Dawn hypertension in pre-Cushing's syndrome: report of two cases].
abstract: Two adrenal tumors were incidentally discovered in the patients with dawn hypertension. They had no clinical features of Cushing's syndrome. These cases were regarded as pre-Cushing's syndrome by endocrinological evaluation. After adrenalectomy, the adrenal hormone regulation was normalized and dawn hypertension disappeared. Our findings suggest that dawn hypertension is a typical clinical sign of pre-Cushing's syndrome and this syndrome may represent a premature status of Cushing's syndrome.
authors.affiliation: Department of Urology, Tokyo Metropolitan Ohtsuka Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Hayashi
authors.forename: A
authors.initials: A
authors.lastname: Yamauchi
authors.forename: K
authors.initials: K
authors.lastname: Hosoda
authors.forename: R
authors.initials: R
authors.lastname: Kakehi
mesh_terms: D000315:Adrenalectomy; D002940:Circadian Rhythm; D003480:Cushing Syndrome / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008875:Middle Aged