title: [Ask-Upmark kidney: a case report].
abstract: A case of Ask-Upmark kidney is presented. An 18-year-old male patient referred to this facility presented with symptoms of hypertension, microscopic hematuria and proteinuria. A hormonal study revealed a high plasma renin activity level. Intravenous pyelography and abdominal computed tomography revealed thinning of the cortex with calyceal dilatation. Arteriography revealed a deep cortical groove in the middle portion of the kidney without renal arterial stenosis. Plasma renin activity of the left renal vein was significantly higher than that of the right renal vein. A left simple nephrectomy was performed under the diagnosis of Ask-Upmark kidney. Postoperatively, plasma renin activity returned to the normal range and a decrease in blood pressure was noted. Recent reports have suggested Ask-Upmark kidney to be a consequence of vesicoureteral reflux rather than a true congenital malformation. Our case indicated no evidence of vesicoureteral reflux and suggests that the lesion was congenital rather than acquired.
authors.affiliation: Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Takase
authors.forename: Y
authors.initials: Y
authors.lastname: Ogo
authors.forename: H
authors.initials: H
authors.lastname: Misaki
authors.forename: M
authors.initials: M
authors.lastname: Moriyama
authors.forename: Y
authors.initials: Y
authors.lastname: Satomi
mesh_terms: D000293:Adolescent; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology*; D007668:Kidney / Q000002:abnormalities* / Q000473:pathology; D008297:Male; D012083:Renin / Q000097:blood
chemical_list: D012083:Renin