The penton base of human adenovirus type 3 has the RGD motif.
The gene encoding the penton base of human adenovirus (Ad) type 3 has been sequenced. The resulting amino-acid sequence has an Arg-Gly-Asp (RGD) motif located near its middle in a hydrophilic region. The same motif is found in serotypes 2, 5 and 12. This sequence was found [Wickham et al., Cell 73 (1993) 309-319] to be involved in the internalisation of Ad2 through an interaction with some specific integrins.
Cuzange
A
A
Institut de Biologie Structurale, Grenoble, France.
Chroboczek
J
J
Jacrot
B
B
D000260:Adenoviruses, Human / Q000235:genetics*; D000595:Amino Acid Sequence; D000259:Aviadenovirus / Q000235:genetics; D001483:Base Sequence; D002213:Capsid / Q000235:genetics*; D036022:Capsid Proteins; D005814:Genes, Viral / Q000235:genetics*; D008969:Molecular Sequence Data
D036022:Capsid Proteins; C043322:penton protein, adenovirus