title: Transparenchymal suture fixation and testicular histology in a prepubertal rat model.
abstract: We evaluate the effect on testicular histology when fine suture materials are used for transparenchymal suture fixation of the testis during orchiopexy in immature Sprague-Dawley rats. Significant inflammatory reactions were observed in all groups of animals with suture fixation regardless of suture size and material. Only 5% of the animals in the dartos pouch control group had an inflammatory response and no inflammation was noted in the nonoperative controls. Although these findings have not been documented in humans, this evidence raises concerns about the impact of surgical technique on the future reproductive capabilities of these testes. Alternatives to transparenchymal suture fixation of the testis should be considered in patients with cryptorchidism and testicular torsion. Sutureless dartos pouch placement may provide adequate fixation during most orchiopexies without risking injury to testicular structure and function.
authors.affiliation: Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, Texas.
authors.forename: T K
authors.initials: TK
authors.lastname: Dixon
authors.forename: M L
authors.initials: ML
authors.lastname: Ritchey
authors.forename: W
authors.initials: W
authors.lastname: Boykin
authors.forename: B
authors.initials: B
authors.lastname: Harper
authors.forename: E
authors.initials: E
authors.lastname: Zeidman
authors.forename: I M
authors.initials: IM
authors.lastname: Thompson
mesh_terms: D000367:Age Factors; D000818:Animals; D003456:Cryptorchidism / Q000601:surgery; D007249:Inflammation / Q000209:etiology / Q000473:pathology; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013536:Suture Techniques; D013537:Sutures; D013737:Testis / Q000473:pathology* / Q000601:surgery*