title: [Corneal pseudo-dystrophic complication caused by contact lenses].
abstract: The authors report the cases of two patients suffering of a rare long-term complication of contact lens wearing. Both patients wore daily soft contact lens for 5 and 8 years respectively. They presented with bilateral central predescemetic avascular haze associated with mild corneal stromal edema, descemetic folds in one patient and polymegethism on endothelial specular microscopic examination. The vision impairment was severe, unilateral in one patient and bilateral in the other. More than one year after removal of the contact lenses, only one patient fully recovered her initial visual acuity. The mechanisms of the onset of this corneal pseudo-dystrophy are discussed. Hypoxia and acidosis of the cornea induced by the contact lens are most probably responsible for this complication through endothelial metabolic dysfunction.
authors.affiliation: Service d'Ophtalmologie, Hôpital Bichat, Paris.
authors.forename: T
authors.initials: T
authors.lastname: Hoang-Xuan
authors.forename: J M
authors.initials: JM
authors.lastname: Laroche
authors.forename: H
authors.initials: H
authors.lastname: Robin
authors.forename: M
authors.initials: M
authors.lastname: Ullern
authors.forename: A
authors.initials: A
authors.lastname: Bron
authors.forename: P
authors.initials: P
authors.lastname: Sabatier
authors.forename: J
authors.initials: J
authors.lastname: Durand
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000209:etiology; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D003315:Cornea / Q000473:pathology*; D015715:Corneal Edema / Q000209:etiology*; D003318:Corneal Opacity / Q000209:etiology*; D004728:Endothelium, Corneal / Q000502:physiology; D005260:Female; D006801:Humans; D006935:Hypercapnia / Q000209:etiology; D000860:Hypoxia / Q000209:etiology; D008875:Middle Aged; D013997:Time Factors
vernacular_title: Complication cornéenne pseudo-dystrophique des lentilles de contact.