title: [Comparison of Nd-Yag laser and strip biopsy in the treatment of extensive adenomas of the rectum].
abstract: This prospective study was carried out in order to compare endoscopic laser therapy and strip biopsy for treatment of large sessile rectal adenomas. Between January 1990 and December 1991, 94 consecutive patients, referred to our Endoscopy Service because of extensive rectal adenoma have been allocated to laser therapy or strip biopsy. The effectiveness of the two techniques was statistically the same from many points of view: complete ablation (76.7% vs 71.4%), recurrence (35.4% vs 30.6%) need for surgical intervention (12% vs 16.6%) and complication rates. However, from our experience, the treatment period was significantly shorter for patients affected by an intermediate sized adenoma and treated with strip biopsy. In both groups, instead, complete, permanent ablation was difficult to obtain in the cases of extensive lesions and in particular if they were localized lower than 5 cm from the anus.
authors.affiliation: II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli.
authors.forename: G D
authors.initials: GD
authors.lastname: De Palma
authors.forename: L
authors.initials: L
authors.lastname: Sivero
authors.forename: C
authors.initials: C
authors.lastname: Caiazzo
authors.forename: E
authors.initials: E
authors.lastname: Di Matteo
authors.forename: G G
authors.initials: GG
authors.lastname: Triscino
authors.forename: C
authors.initials: C
authors.lastname: Catanzano
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000379:methods*; D004724:Endoscopy; D005260:Female; D006801:Humans; D007417:Intestinal Polyps / Q000601:surgery*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000601:surgery*
vernacular_title: Confronto tra Nd-YAG laser e strip biopsy nel trattamento degli adenomi estesi del retto.