Traditional herbal remedies used for the treatment of urinary schistosomiasis in Zimbabwe.
A total of 286 traditional healers, 85% of them registered with the Zimbabwe National Traditional Healers' Association (ZINATHA), in five administrative provinces of Zimbabwe, were interviewed to assess their knowledge about the signs and symptoms of urinary schistosomiasis. Information on the names of plants used to treat Schistosoma haematobium infections was solicited. Haematuria was mentioned by 99% of the traditional healers to be the most obvious sign of S. haematobium infection. General body weakness, increased urinary frequency and pain on micturition also were reported to be some of the signs of infection. Eight plant materials were identified as the most commonly used for the treatment of S. haematobium. The plants were identified and parts collected to investigate their antischistosomal properties. The plant materials were prepared according to the guidelines of the traditional healers and their efficacy determined by administering the crude extracts orally to hamsters infected with S. haematobium cercariae. The results obtained suggested that plant extracts from Abrus precatorius (Leguminosae), Pterocarpus angolensis (Leguminosae) and Ozoroa insignis (Anacardiaceae) were lethal to adult schistosomes.
Ndamba
J
J
Blair Research Laboratory, Ministry of Health, Causeway, Harare, Zimbabwe.
Nyazema
N
N
Makaza
N
N
Anderson
C
C
Kaondera
K C
KC
D000328:Adult; D000818:Animals; D006224:Cricetinae; D005260:Female; D006801:Humans; D008297:Male; D016488:Medicine, African Traditional; D008875:Middle Aged; D010936:Plant Extracts / Q000302:isolation & purification / Q000627:therapeutic use*; D011223:Praziquantel / Q000627:therapeutic use; D012553:Schistosomiasis haematobia / Q000188:drug therapy* / Q000503:physiopathology; D015030:Zimbabwe
D010936:Plant Extracts; D011223:Praziquantel