title: [Surgical therapy of pancreatic carcinoma--indications and results].
abstract: Primary malignant neoplasms of the pancreas can occur as ductal adenocarcinoma in up to 80% and as a carcinoma of the exocrine or endocrine parenchyma in up to 20%. The treatment of pancreatic cancer is tumor resection. The surgical procedure depends on the tumor site: subtotal pancreatectomy, total or partial duodenopancreatectomy (Whipple's operation). The morbidity ranges from 5 to 15% and the mortality from 2 to 10%. Pancreatic carcinoma has an extremely poor prognosis, the median survival ranges from three to six months, the 5-year survival rate is 2 to 8%. These results are caused by mostly advanced tumors at the time of diagnosis. Early tumor stages with a 5-year survival rate up to 40% account for only 10% of the resected tumors; therefore, after tumor resection, recurrent disease occurs in up to 90%.
authors.affiliation: Abteilung Allgemeine Chirurgie mit Poliklinik der Chirurgischen Universitäts-Klinik, Freiburg.
authors.forename: E H
authors.initials: EH
authors.lastname: Farthmann
authors.forename: G
authors.initials: G
authors.lastname: Ruf
mesh_terms: D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D003952:Diagnostic Imaging; D006801:Humans; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D011379:Prognosis
vernacular_title: Chirurgische Therapie des Pankreaskarzinoms--Indikation und Resultate.