Concomitant chemoradiotherapy for non-small cell lung cancer.
Concomitant chemoradiotherapy represents an investigational approach to the treatment of locoregionally advanced non-small cell lung cancer. The theoretical rationale, and clinical experience are reviewed in brief. Clinical trials conducted at the University of Chicago are summarized.
Vokes
E E
EE
Department of Medicine, University of Chicago, IL 60637-1470.
Haraf
D J
DJ
Hoffman
P C
PC
Bitran
J D
JD
Ferguson
M K
MK
Golomb
H M
HM
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D002641:Chicago / Q000453:epidemiology; D002945:Cisplatin / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D017321:Clinical Trials, Phase I as Topic; D017322:Clinical Trials, Phase II as Topic; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage; D007155:Immunologic Factors / Q000627:therapeutic use; D016898:Interferon-alpha / Q000627:therapeutic use; D002955:Leucovorin / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D010865:Pilot Projects; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
D007155:Immunologic Factors; D016898:Interferon-alpha; D002945:Cisplatin; D002955:Leucovorin; D005472:Fluorouracil; D006918:Hydroxyurea