title: [A case of dissecting aortic aneurysm and presence of anti-Jr(a) antibody].
abstract: A 66-year-old woman was diagnosed as a DeBakey type II dissecting aortic aneurysm with angiography and CT. Antibody screening revealed circulating anti-Jr(a) antibody. Preoperatively, erythropoietin was administered twice a week. Over 24 days, a total of 1200 ml of her blood was removed and stored for autologous transfusion. The dissecting ascending aorta was replaced with the aid of cardiopulmonary bypass. The post operative course was uneventful. By using erythropoietin, pre-donated autologous blood, cell saver, aprotinin and transfusion of fresh autologous blood, it was possible to perform cardiovascular surgery on this patient who had an abnormal antibody. This patient is the first case of repair or dissecting aortic aneurysm with anti-Jr(a) antibody in Japan.
authors.affiliation: Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Imamura
authors.forename: M
authors.initials: M
authors.lastname: Sakuma
authors.forename: N
authors.initials: N
authors.lastname: Shiiya
authors.forename: J
authors.initials: J
authors.lastname: Oba
authors.forename: M
authors.initials: M
authors.lastname: Miyama
authors.forename: K
authors.initials: K
authors.lastname: Yasuda
mesh_terms: D000368:Aged; D000784:Aortic Dissection / Q000276:immunology / Q000601:surgery*; D001011:Aorta / Q000601:surgery; D001014:Aortic Aneurysm / Q000276:immunology / Q000601:surgery*; D001789:Blood Group Antigens / Q000276:immunology*; D001804:Blood Transfusion, Autologous; D001807:Blood Vessel Prosthesis; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000032:analysis*
chemical_list: D001789:Blood Group Antigens; D007518:Isoantibodies