Localisation of the gene for multiple endocrine neoplasia type 2A to a 480 kb region in chromosome band 10q11.2.
A YAC contig has been constructed spanning 1.1 Mb of human chromosome band 10q11.2 which encompasses three markers (D10S141, RET, D10S94) closely linked to the gene for MEN 2A. This physical linkage group is ordered cen-D10S141-RET-D10S94-qter, and must include MEN2A, which lies in a 480 kb region between flanking markers D10S141 and D10S94.
Mole
S E
SE
Department of Pathology, University of Cambridge, UK.
Mulligan
L M
LM
Healey
C S
CS
Ponder
B A
BA
Tunnacliffe
A
A
D001483:Base Sequence; D002874:Chromosome Mapping; D015825:Chromosomes, Fungal; D002879:Chromosomes, Human, Pair 10; D004247:DNA / Q000235:genetics; D015723:Gene Library; D008040:Genetic Linkage; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D008969:Molecular Sequence Data; D009377:Multiple Endocrine Neoplasia / Q000235:genetics*; D009857:Oncogenes; D015183:Restriction Mapping
D005819:Genetic Markers; D004247:DNA