[Classification of the toxicity of chemical compounds on the basis of statistical analysis of lethal dose and concentration curves].
The results of peroral administration of 4451 chemicals and inhalation of 276 chemicals into rats and mice were described by lethal doses and concentrations distribution curves, which were then subjected to statistic analysis. All that helped to base the classification of chemical toxicity in single exposure.
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D000280:Administration, Inhalation; D000284:Administration, Oral; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D007928:Lethal Dose 50; D051379:Mice; D051381:Rats
Klassifikatsiia toksichnosti khimicheskikh soedineniĭ na osnove statisticheskogo analiza krivykh raspredeleniia smertel'nykh doz i kontsentratsiĭ.