Immunoassay reagents for psychoactive drugs. Part 4. Quantitative determination of amitriptyline and nortriptyline by fluorescence polarization immunoassay.
Methods for the quantitative determination of amitriptyline and nortriptyline by fluorescence polarization immunoassay (FPIA) is described. One immunoassay allows for the accurate quantification of amitriptyline in the presence of nortriptyline while the second immunoassay allows for the accurate quantification of nortriptyline in the presence of amitriptyline.
Adamczyk
M
M
Abbott Laboratories, Abbott Park, Illinois 60064.
Fishpaugh
J R
JR
Harrington
C A
CA
Hartter
D E
DE
Vanderbilt
A S
AS
Orsulak
P
P
Akers
L
L
D000639:Amitriptyline / Q000097:blood* / Q000276:immunology; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003429:Cross Reactions; D016231:Fluorescence Polarization Immunoassay; D005456:Fluorescent Dyes; D006801:Humans; D007202:Indicators and Reagents; D009661:Nortriptyline / Q000097:blood* / Q000276:immunology; D011619:Psychotropic Drugs / Q000097:blood*; D011817:Rabbits / Q000276:immunology; D012997:Solvents
D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D011619:Psychotropic Drugs; D012997:Solvents; D000639:Amitriptyline; D009661:Nortriptyline