Neuroleptic malignant syndrome and malignant hyperthermia. Important issues for the medical consultant.
Neuroleptic malignant syndrome and malignant hyperthermia share two cardinal clinical features: hypothermia and rigidity. Both syndromes can result in rhabdomyolysis and have high mortality rates if left untreated. This article reviews each syndrome and its pathogenesis and treatment.
Heiman-Patterson
T D
TD
Department of Neurology, Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
D003620:Dantrolene / Q000627:therapeutic use; D003937:Diagnosis, Differential; D015259:Dopamine Agents / Q000627:therapeutic use; D006801:Humans; D008305:Malignant Hyperthermia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D012017:Referral and Consultation
D015259:Dopamine Agents; D003620:Dantrolene