Efficacy of sulthiame (Ospolot) on motor partial seizure status during sleep in a patient with motor cortex epilepsy.
An 18-year-old female patient with a particular form of intractable motor cortex epilepsy, in which motor partial seizure status occurred only during sleep every night, was reported focusing on the drastic efficacy of sulthiame on the seizure status. Moreover, the present study demonstrated that single photon emission computed tomography (SPECT) and pulse oximetry examinations, both of which were performed in the ictal state, were useful for the regional diagnosis of the epileptic focus and observations of the seizure frequency, respectively. The therapeutic effect, epileptic picture and clinical examinations described here appear to be relatively rare in the literature, and therefore, this case report may be of clinical significance.
Jibiki
I
I
Department of Neuropsychiatry, Kanazawa University School of Medicine, Japan.
Urata
K
K
Matsuda
H
H
Furuta
H
H
Yamaguchi
N
N
Hisada
K
K
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007360:Intelligence / Q000187:drug effects; D008279:Magnetic Resonance Imaging; D009044:Motor Cortex / Q000187:drug effects / Q000503:physiopathology*; D010092:Oximetry; D012890:Sleep / Q000502:physiology*; D013843:Thiazines / Q000008:administration & dosage / Q000627:therapeutic use*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D014888:Wechsler Scales
D013843:Thiazines