title: Serotypes of Streptococcus pneumoniae blood culture isolates from adults in Franklin County, Ohio.
abstract: Isolates of Streptococcus pneumoniae in cultures of blood from 258 adults seen in 10 Franklin County, Ohio, hospitals from 1991 and 1992 were serotyped. Most strains (230 [89.2%]) belonged to serotypes that are included in the current pneumococcal vaccine. An additional 16 isolates (6.2%) were immunologically related to strains with serotypes that are included in the vaccine. Only 12 isolates (4.6%) were not covered by the vaccine. The rate of mortality from pneumococcal bacteremia in adults remains high (20%). While recent studies have documented the efficacy of the pneumococcal vaccine for preventing pneumococcal bacteremia (56 to 70%), use of the pneumococcal vaccine in susceptible patients by physicians remains low (19% in Franklin County). Additional efforts need to be expended to increase the use of the pneumococcal vaccine.
authors.affiliation: Department of Internal Medicine, Ohio State University, Columbus 43210.
authors.forename: J F
authors.initials: JF
authors.lastname: Plouffe
authors.forename: S K
authors.initials: SK
authors.lastname: Moore
authors.forename: R
authors.initials: R
authors.lastname: Davis
authors.forename: R R
authors.initials: RR
authors.lastname: Facklam
mesh_terms: D000328:Adult; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality; D001428:Bacterial Vaccines; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality; D006801:Humans; D009820:Ohio / Q000453:epidemiology; D012621:Seasons; D012703:Serotyping; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000302:isolation & purification; D014611:Vaccination / Q000706:statistics & numerical data
chemical_list: D001428:Bacterial Vaccines