Peak bone mass, bone loss and risk of fracture.
Both peak bone mass and bone loss contribute to subsequent fracture risk. Other variables such as architectural abnormalities, microdamage, geometric properties, and trauma probably contribute as well. Until the contribution of these other potentially important risk factors can be quantified, it will be difficult to determine precisely the relative importance of peak bone mass and subsequent bone loss in the etiology of fractures.
Johnston
C C
CC
Department of Medicine, Indiana University School of Medicine, Indianapolis.
Slemenda
C W
CW
D015519:Bone Density / Q000502:physiology*; D001862:Bone Resorption / Q000503:physiopathology; D050723:Fractures, Bone / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D010024:Osteoporosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D012307:Risk Factors