title: High-resolution CT of the lung in asbestos-exposed subjects. Comparison of low-dose and high-dose HRCT.
abstract: The lowest possible mAs settings for high-resolution CT (HRCT) were studied on 45 individuals with suspected asbestos-related lung disease. All patients were investigated with 5 to 6 high-dose HRCT images (120 kVp/160 mA/2 s) at 3-cm intervals. At a selected level 4 additional low-dose images were obtained on each patient with lower mAs settings (100 mA/2 s, 80 mA/2 s, 60 mA/2 s, 30 mA/2 s). Thirty-seven subjects out of 45 had HRCT lesions compatible with asbestosis. HRCT images obtained with as low as 60 mA/2 s settings clearly showed pleural tractions and thickenings, parenchymal bands, honeycombing and subpleural curvilinear shadows, whereas in the evaluation of subpleural short lines and ground glass findings 80 mA/2 s were required. The lowest setting, 30 mA/2 s, was sufficient only in detecting and evaluating pleural tractions and thickenings. We conclude that 160 mAs yield good quality HRCT images, with substantial decrease of radiation dose, for the evaluation of asbestos-related lesions.
authors.affiliation: Department of Diagnostic Radiology, Turku University Hospital, Finland.
authors.forename: M L
authors.initials: ML
authors.lastname: Majurin
authors.forename: M
authors.initials: M
authors.lastname: Varpula
authors.forename: T
authors.initials: T
authors.lastname: Kurki
authors.forename: L
authors.initials: L
authors.lastname: Pakkala
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001195:Asbestosis / Q000000981:diagnostic imaging*; D001987:Bronchiectasis / Q000000981:diagnostic imaging; D001991:Bronchitis / Q000000981:diagnostic imaging; D002908:Chronic Disease; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010995:Pleural Diseases / Q000000981:diagnostic imaging; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging