title: Radiologic appearance of the irradiated larynx. Part I. Expected changes.
abstract: OBJECTIVE
  To present the expected appearance of the irradiated larynx and neck as seen at computed tomography (CT).
  
  
  METHODS
  Sixty-one patients with primary squamous cell carcinoma of the larynx or hypopharynx were treated with radiation therapy. All patients underwent CT before and after treatment.
  
  
  RESULTS
  Expected changes include symmetric thickening of the epiglottis, aryepiglottic folds, and false cords and increased attenuation of the paralaryngeal fat. The posterior pharyngeal wall tends to thicken and its mucosa enhances; retropharyngeal space edema is common. Glottic changes include increased attenuation of the paraglottic fat planes and thickening of the anterior and posterior commissures. Subglottic changes include thickening of the mucosa and submucosa. Soft-tissue changes include skin and platysmal thickening, as well as reticulation and increased attenuation of the subcutaneous and deeper fat.
  
  
  CONCLUSIONS
  Familiarization with expected radiologic changes is essential for interpretation of CT images of the irradiated larynx so that such changes are not mistaken for signs of persistent or recurrent tumor.
authors.affiliation: Department of Radiology, University of Florida College of Medicine, Shands Teaching Hospital, Gainesville.
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherji
authors.forename: A A
authors.initials: AA
authors.lastname: Mancuso
authors.forename: I M
authors.initials: IM
authors.lastname: Kotzur
authors.forename: W M
authors.initials: WM
authors.lastname: Mendenhall
authors.forename: P S
authors.initials: PS
authors.lastname: Kubilis
authors.forename: R P
authors.initials: RP
authors.lastname: Tart
authors.forename: W R
authors.initials: WR
authors.lastname: Lee
authors.forename: D
authors.initials: D
authors.lastname: Freeman
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000532:radiotherapy*; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000532:radiotherapy*; D007830:Larynx / Q000000981:diagnostic imaging* / Q000528:radiation effects*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D013997:Time Factors; D014057:Tomography, X-Ray Computed