title: The sequence of 29.7 kb from the right arm of chromosome II reveals 13 complete open reading frames, of which ten correspond to new genes.
abstract: We have determined the complete nucleotide sequence of a 29.7 kb segment from the right arm of chromosome II carried by the cosmid alpha 61. The sequence encodes the 3' region of the IRA1 gene and 13 complete open reading frames, of which ten correspond to new genes and three (CIF1, ATPsv and CKS1) have been sequenced previously. The density of protein coding sequences is particularly high and corresponds to 84% of the total length. Two new genes encode membrane proteins, one of which is particularly large, 273 kDa. In one case (ATPsv), the comparison of our sequence and the published sequence reveals significant differences.
authors.affiliation: Centre de Génétique Moléculaire, Laboratoire propre du CNRS associé à l'Université Pierre et Marie Curie, Gif-sur-Yvette, France.
authors.forename: A M
authors.initials: AM
authors.lastname: Bécam
authors.forename: C
authors.initials: C
authors.lastname: Cullin
authors.forename: E
authors.initials: E
authors.lastname: Grzybowska
authors.forename: F
authors.initials: F
authors.lastname: Lacroute
authors.forename: F
authors.initials: F
authors.lastname: Nasr
authors.forename: O
authors.initials: O
authors.lastname: Ozier-Kalogeropoulos
authors.forename: A
authors.initials: A
authors.lastname: Palucha
authors.forename: P P
authors.initials: PP
authors.lastname: Slonimski
authors.forename: M
authors.initials: M
authors.lastname: Zagulski
authors.forename: C J
authors.initials: CJ
authors.lastname: Herbert
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000595:Amino Acid Sequence; D018797:Cell Cycle Proteins; D015825:Chromosomes, Fungal; D005800:Genes, Fungal / Q000235:genetics*; D005964:Glucosyltransferases / Q000235:genetics; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics*; D015183:Restriction Mapping; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
chemical_list: D048868:Adaptor Proteins, Signal Transducing; C081185:CKS1 protein, S cerevisiae; D018797:Cell Cycle Proteins; D029701:Saccharomyces cerevisiae Proteins; D005964:Glucosyltransferases; C023180:trehalose-6-phosphate synthase