[A case of drug induced pneumonitis caused by saiboku-To].
We report a case of drug induced pneumonitis caused by Saiboku-To. A 60-year-old woman was admitted to our hospital because of dry cough, fever and severe dyspnea after taking Saiboku-To. Blood gas analysis showed marked hypoxemia. Chest X-ray obtained on admission showed diffuse ground glass shadows in bilateral lung fields, and computed tomography showed diffuse interstitial shadows. Following steroid pulse therapy, clinical symptoms, hypoxemia and chest X-ray findings were ameliorated. Against medical advice, she took another Chinese medicine with ingredients similar to those of Saiboku-To. She complained of dry cough, fever and dyspnea and the chest X-ray again revealed diffuse ground glass shadows in both lung fields. Lymphocyte stimulation test against Saiboku-To and the patch test for Saiboku-To were positive. Therefore, we diagnosed this case as having pneumonitis due to Saiboku-To. This is first report of interstitial pneumonitis due to Saiboku-To.
Temaru
R
R
Department of Internal Medicine, Toyama Prefecture Saisei Kai Takaoka Hospital, Japan.
Yamashita
N
N
Matsui
S
S
Ohta
T
T
Kawasaki
A
A
Kobayashi
M
M
D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced*; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D020835:Medicine, Kampo; D008875:Middle Aged
D004365:Drugs, Chinese Herbal; C045086:saiboku-to