Seckel syndrome in a Yemeni family in Saudi Arabia.
We studied a 28-year-old Yemeni woman with typical Seckel syndrome. Two deceased sibs, a twin sister and a brother, had also been affected. The father of these individuals was married to his cousin's daughter: the pedigree suggests autosomal recessive inheritance. Classical Seckel syndrome has not been reported previously in Arabs, and this appears to be the first report from the Middle East.
Krishna
A G
AG
Department of Medicine, National Guard King Khalid Hospital, Jeddah, Saudi Arabia.
Scrimgeour
E M
EM
Zawawi
T H
TH
D000328:Adult; D003241:Consanguinity; D004392:Dwarfism / Q000235:genetics; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000235:genetics; D008297:Male; D008831:Microcephaly / Q000235:genetics; D009958:Orofaciodigital Syndromes / Q000235:genetics*; D010375:Pedigree; D012529:Saudi Arabia; D015006:Yemen / Q000208:ethnology