title: [Drinking water and leukemia].
abstract: A retrospective cohort study was conducted to investigate the relationship between drinking water contamination and risk of leukemia in human being. It was found that the leukemia incidence rate of group D who drank the tap-water from Donghu Lake was significantly higher than that of the groups C and H who drank the tap-water from Changjiang River and Hangjiang River, RR = 1.77, 95% CL = 1.36-2.30, P < 0.01. But the difference between group C and group H is not significant. By using the sex- age-strata analysis; trend and correlation analysis, the results showed that there was a significant positive correlation between the RR of incidence of leukemia and tap-water mutagenicity. It was also connected with pollution of halogenated hydrocarbons in drinking water.
authors.affiliation: Tongji Medical University, Wuhan.
authors.forename: J C
authors.initials: JC
authors.lastname: Lu
authors.forename: L
authors.initials: L
authors.lastname: Shi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000032:analysis*; D015994:Incidence; D007223:Infant; D007938:Leukemia / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009152:Mutagenicity Tests; D012189:Retrospective Studies; D012307:Risk Factors; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014881:Water Supply / Q000032:analysis
chemical_list: D006846:Hydrocarbons, Halogenated; D014874:Water Pollutants, Chemical