Cerebrovascular stenoses with cerebral infarction in a child with Williams syndrome.
We report on a patient with Williams syndrome who suffered a cerebrovascular accident. Clinical evaluation demonstrated the presence of carotid and cerebral arterial stenoses. We believe these lesions led to acute cerebrovascular ischemia and a non-hemorrhagic cerebral infarction. It is possible the stenoses were exacerbated by a vasculitis. The stenoses were identified by both invasive and noninvasive imaging studies. These studies may have a role in the evaluation of persons with Williams syndrome.
Ardinger
R H
RH
Department of Pediatrics, University of Kansas School of Medicine, Kansas City 66160-7330.
Goertz
K K
KK
Mattioli
L F
LF
D000015:Abnormalities, Multiple; D002545:Brain Ischemia / Q000209:etiology; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000150:complications* / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002539:Cerebral Arterial Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002544:Cerebral Infarction / Q000209:etiology*; D002675:Child, Preschool; D005149:Facial Expression; D006130:Growth Disorders / Q000150:complications; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D013577:Syndrome