Receptor binding specificity and pathogenicity of Escherichia coli F165-positive strains isolated from piglets and calves and possessing pap related sequences.
Most of 82 F165-positive Escherichia coli isolated from calves and piglets with diarrhea or septicemia and possessing pap related sequences caused mannose-resistant, neuraminidase-resistant hemagglutination of human and bovine erythrocytes. Less than half of these isolates demonstrated binding specificity for the alpha-D-galactosyl-(1-4)-beta-D-galactopyranose or galactose-N-acetyl-alpha-(1-3) galactose-N-acetyl moieties recognized by P and F (or Prs) adhesins respectively. Binding specificity for the galactose-N-acetyl-alpha-(1-3) galactose-N-acetyl moiety was associated with isolates causing septicemia in newborn piglets.
Fairbrother
J
J
GREMIP, Faculté de Médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec.
Harel
J
J
Forget
C
C
Desautels
C
C
Moore
J
J
D018830:Adhesins, Escherichia coli; D000818:Animals; D016470:Bacteremia / Q000382:microbiology / Q000662:veterinary; D001422:Bacterial Adhesion; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D003967:Diarrhea / Q000382:microbiology / Q000662:veterinary; D004926:Escherichia coli / Q000378:metabolism* / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D006386:Hemagglutination Tests; D011971:Receptors, Immunologic / Q000378:metabolism; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*
D018830:Adhesins, Escherichia coli; D001425:Bacterial Outer Membrane Proteins; D011971:Receptors, Immunologic; C047105:bacterial adhesin receptor