title: Feto-maternal plasma phenylalanine concentration gradient from 19 weeks gestation to term.
abstract: Plasma phenylalanine concentrations in fetal blood, obtained by cordocentesis, were compared with simultaneous peripheral venous plasma phenylalanine levels in mothers. The feto-maternal phenylalanine concentration ratio showed a gradual decrease from 19 weeks of gestation to term with an overall ratio of 1.35 +/- 0.42 (mean +/- S.D., n = 14).
authors.affiliation: Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: W E
authors.initials: WE
authors.lastname: Schoonheyt
authors.forename: J T
authors.initials: JT
authors.lastname: Clarke
authors.forename: W B
authors.initials: WB
authors.lastname: Hanley
authors.forename: J M
authors.initials: JM
authors.lastname: Johnson
authors.forename: D C
authors.initials: DC
authors.lastname: Lehotay
mesh_terms: D002852:Chromatography, Ion Exchange; D000013:Congenital Abnormalities / Q000097:blood / Q000000981:diagnostic imaging; D017218:Cordocentesis; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D010649:Phenylalanine / Q000097:blood*; D010661:Phenylketonurias / Q000097:blood; D011247:Pregnancy; D014463:Ultrasonography
chemical_list: D010649:Phenylalanine