A lamellar liquid crystal with fosinopril sodium.
The location and conformation of fosinopril sodium (FS) in a lamellar liquid crystal of water, sodium dodecyl sulfate, and decanol was studied by low-angle X-ray diffraction. The result showed the FS molecule to be located within the amphiphilic part of the liquid crystalline structure with the polar parts anchored at the water/polar part interface. An area per molecule in the range of 95-100 A2 showed not only the polar groups but also the benzene ring to be located at this interface.
Friberg
S E
SE
Center for Advanced Materials Processing, Clarkson University, Potsdam, NY 13699-5814.
Moaddel
T
T
Morris
K R
KR
Abramowitz
R
R
Amsberry
K L
KL
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003460:Crystallization; D017328:Fosinopril / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D014961:X-Ray Diffraction
D017328:Fosinopril