[Immunologic manifestations in myelodysplastic syndrome].
We describe three patients with primary myelodysplastic syndrome and immunological manifestations. One had painful cutaneous plaques, arthritis and peripheral neuropathy, another showed cutaneous vasculitis, and a third had Sweet's syndrome. All patients responded dramatically to steroids. Before treatment the patient with Sweet's syndrome had high serum levels of interleukin 6 (IL-6), which were reduced to zero after treatment with steroids. Myelodysplastic syndrome should be considered when evaluating patients with immunological or rheumatic manifestations associated with one or more cytopenias.
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Medisinsk avdeling, Regionsykehuset i Trondheim.
Lamvik
J
J
Matre
J
J
D000368:Aged; D001168:Arthritis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000473:pathology; D016463:Sweet Syndrome / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D014657:Vasculitis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology
Immunologiske manifestasjoner ved myelodysplastisk syndrom.