title: Using urokinase to restore patency in double lumen catheters.
abstract: All hemodialysis patients with temporary or permanent double lumen catheters are at risk for catheter occlusion. Clinical outcomes and cost-effectiveness of using urokinase, a thrombolytic agent, to declot occluded double lumen dialysis catheters were evaluated for 2 years. Patency was restored in 95 of 102 catheters. These data support the use of urokinase to safely and effectively restore patency, thereby extending the length of time a catheter can be used for dialysis.
authors.forename: C
authors.initials: C
authors.lastname: Northsea
mesh_terms: D002408:Catheters, Indwelling; D015400:Clinical Nursing Research; D003362:Cost-Benefit Analysis; D004868:Equipment Failure; D006801:Humans; D011785:Quality Assurance, Health Care; D006435:Renal Dialysis / Q000295:instrumentation*; D014568:Urokinase-Type Plasminogen Activator
chemical_list: D014568:Urokinase-Type Plasminogen Activator