title: Pituitary response of cryptorchid dogs to LH-RH-analogue before and after sexual maturation.
abstract: An LH-RH-analogue (LH-RH-A) was administered to 5 cryptorchid (CR) and 6 normal beagles before and after sexual maturation and peripheral plasma LH and testosterone levels were measured. The response patterns of plasma LH levels for LH-RH-A in the CR dogs were similar to those in the normal dogs before and after sexual maturation. It was therefore demonstrated there is little difference in pituitary response to LH-RH-A in the CR and normal dogs. However, the maximum levels of testosterone in the CR dogs were generally lower than those in the normal dogs.
authors.affiliation: Department of Reproduction, Nippon Veterinary and Animal Science University, Tokyo, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Kawakami
authors.forename: S
authors.initials: S
authors.lastname: Hirayama
authors.forename: T
authors.initials: T
authors.lastname: Tsutsui
authors.forename: A
authors.initials: A
authors.lastname: Ogasa
mesh_terms: D000818:Animals; D003456:Cryptorchidism / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood* / Q000503:physiopathology; D004285:Dogs; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000494:pharmacology; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects* / Q000503:physiopathology; D012741:Sexual Maturation / Q000502:physiology*; D013739:Testosterone / Q000097:blood
chemical_list: D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; C009936:fertirelin