Gliomas in patients with acquired immune deficiency syndrome.
BACKGROUND
Ten percent of patients with acquired immune deficiency syndrome (AIDS) have intracerebral mass lesions of which the majority are due either to toxoplasmosis or primary central nervous system lymphomas.


METHODS
Three patients with AIDS presented with solitary intracerebral mass lesions and were found by pathologic examination to have gliomas.


RESULTS
After surgery, all patients were treated with radiotherapy and procarbazine, comustine, and vincristine multiagent chemotherapy. Median follow-up is 12 months.


CONCLUSIONS
Occasionally, patients with AIDS and intracerebral mass lesions have primary nonlymphomatous brain tumors, an occurrence not related clearly to underlying immunoincompetence.
Chamberlain
M C
MC
Department of Neurosciences, University of California, San Diego 92103-0812.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D005909:Glioblastoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D018242:Neuroectodermal Tumors, Primitive / Q000150:complications* / Q000473:pathology