title: The mouse lysyl oxidase gene (Lox) resides on chromosome 18.
abstract: Lysyl oxidase initiates crosslink formation of the connective tissue matrix. This enzyme can also revert the ras phenotype in mouse NIH 3T3-transformed cells. Even though lysyl oxidase may participate in many different biological processes, its chromosomal assignment in the mouse genome remains to be addressed. Southern analysis of a panel of Chinese hamster x mouse somatic cell hybrids was utilized to assign the lysyl oxidase gene (Lox) to mouse Chromosome 18.
authors.affiliation: Center for Molecular Biology, Wayne State University, Detroit, MI.
authors.forename: Y S
authors.initials: YS
authors.lastname: Chang
authors.forename: D M
authors.initials: DM
authors.lastname: Svinarich
authors.forename: T P
authors.initials: TP
authors.lastname: Yang
authors.forename: S A
authors.initials: SA
authors.lastname: Krawetz
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D006224:Cricetinae; D006822:Hybrid Cells; D051379:Mice / Q000235:genetics*; D008249:Protein-Lysine 6-Oxidase / Q000235:genetics*
chemical_list: D008249:Protein-Lysine 6-Oxidase