title: [Preliminary evaluation of efficacy for the preparation DNCG-compositum in treatment of atopic bronchial asthma in children].
abstract: Preparations, in which composition disodium cromoglycate goes into, have been for many years the admitted way of bronchial asthma treatment. The introduction, to the therapy, of preparation that contains reproterol as well makes possible the early remission of disease symptoms. The aim of the study was the estimation of the effectiveness of DNCG-comp. preparation. Twenty one children, aged 7-17 years, with recognized bronchial asthma were examined. The atopic basis of the disease was found on the ground of results of skin prick tests, and elevated concentration of serum IgE and positive atopic family interview. We resigned the hitherto treatment for 3 days, carried out the spirometric measurements (PEF, FEV1, FEV1%VC, MEF25,50,75). DNCG-comp. was given 4-times per twenty-four hours in 2 inhalations at each time, for three weeks. Every day, the PEF value and the score of disease symptoms were established. After the study, side effects were not observed and final results of spirometric estimation evidence the possibility of wide application of DNCG-comp. preparation in the treatment of bronchial asthma in childhood.
authors.affiliation: III Katedry i Kliniki Pediatrii i Alergologii Akademii Medycznej we Wrocławiu.
authors.forename: A
authors.initials: A
authors.lastname: Boznański
authors.forename: M
authors.initials: M
authors.lastname: Domanasiewicz
authors.forename: D
authors.initials: D
authors.lastname: Rudzka
authors.forename: I
authors.initials: I
authors.lastname: Pirogowicz
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002648:Child; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D009921:Metaproterenol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012882:Skin Tests; D013147:Spirometry; D013806:Theophylline / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D001993:Bronchodilator Agents; D004338:Drug Combinations; C014792:reproterol; D009921:Metaproterenol; D013806:Theophylline; D004205:Cromolyn Sodium
vernacular_title: Wstepna ocena skuteczności preparatu DNCG-compositum w leczeniu atopowej astmy oskrzelowej u dzieci.