title: [Anti-anemia therapy with prophylactic administration of Fe2+ in normal pregnancy and its effect on prepartum hematologic parameters in the mother and neonate].
abstract: Eighty-four non-anaemic pregnant women were treated, starting between the 20th-24th week of Pregnancy, with Actiferrin Compositum--1 capsule per day--from the 36th with 2 capsules per day up to childbirth. The group was compared with the results in 57 non-anaemic not treated pregnant women. Haematological parameters were recorded before the onset of treatment, during the first stage of labour and in neonates on the first day after delivery. By means of the non-paired t-test no significant differences were disclosed between the groups; nevertheless the percentage values of haemoglobin, haematocrit, erythrocytes and serum iron were higher in the treated group, as compared with the non-treated one. Also the ferritin values in neonates of the non-treated group were lower, as compared with the treated group. The paired t-test was highly significant in the Actiferrin treated patients as regards haemoglobin, haematocrit and transferrin values. The results provide evidence that it is indicated to administer as a routine measure Actiferrin Compositum to all pregnant women as prevention of pre-partum anaemia of the mother and low ferritin levels in the neonate.
authors.affiliation: II. gynekologicko-porodnická klinika LF MU, Brno.
authors.forename: A
authors.initials: A
authors.lastname: Roztocil
authors.forename: M
authors.initials: M
authors.lastname: Charvátová
authors.forename: L
authors.initials: L
authors.lastname: Harastová
authors.forename: J
authors.initials: J
authors.lastname: Zahrádková
authors.forename: P
authors.initials: P
authors.lastname: Studeník
authors.forename: V
authors.initials: V
authors.lastname: Sochorová
authors.forename: H
authors.initials: H
authors.lastname: Vajcíková
authors.forename: V
authors.initials: V
authors.lastname: Drastichová
authors.forename: T
authors.initials: T
authors.lastname: Burnog
authors.forename: L
authors.initials: L
authors.lastname: Pilka
mesh_terms: D000747:Anemia, Hypochromic / Q000097:blood / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007501:Iron / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000517:prevention & control*; D011446:Prospective Studies
chemical_list: D007501:Iron
vernacular_title: Antianemická lécba fyziologických tĕhotných a její vliv na prepartální hematologické parametry matky a novorozence profylaktickým podáním Fe2+.