title: Effects of antibacterial agents on transformation of fatty acids in sediment from a marine fish farm site.
abstract: The conversion of fatty acids in marine fish farm sediment from a simulated abandoned site was investigated. Five containers of aquaculture sediment were followed in 1 year. Antibacterial agents: oxytetracycline, flumequine and oxolinic acid, respectively, were added to three of the containers, while two were controls. The fatty acid composition in the sediment was examined by direct methanolysis on sediment, high-resolution gas chromatography and multivariate data-analysis. The total amount of fatty acids decreased strongly in all containers and the fatty acid profile in the sediment changed clearly towards the profile of natural, unaffected sediment with time. During the experimental period, the added drugs had a retarding effect on the transformation of fatty acids in the sediment. This effect, however, was not detectable after 10 months.
authors.affiliation: Department of Chemistry, University of Bergen, Norway.
authors.forename: R I
authors.initials: RI
authors.lastname: Johnsen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects / Q000378:metabolism*; D001711:Biotransformation / Q000187:drug effects; D005227:Fatty Acids / Q000493:pharmacokinetics*; D005398:Fisheries; D012623:Seawater; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics*
chemical_list: D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D014874:Water Pollutants, Chemical