Familial chronic myelocytic leukaemia-like syndrome probably of congenital origin.
Three Saudi siblings presented with clinical features of chronic myelocytic leukaemia in early infancy. Their parents are first cousins. The mother was 22 years old during her first pregnancy. She had no history of abortion. The possibility of this familial disorder being congenital is discussed.
Lardi
A A
AA
Department of Paediatrics, King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.
Taha
O M
OM
al-Jefri
A
A
Ahmed
M A
MA
D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000151:congenital / Q000235:genetics* / Q000503:physiopathology; D008297:Male