Paratesticular rhabdomyosarcoma (RMS) and paraaortic lymphadenectomy.
This study is based on the experience of the Italian Cooperative Studies "AIEOP-RMS 79 and RMS 88". Between October 1979 and December 1989 299 children under 15 years of age with a histologically proven rhabdomyosarcoma (RMS) were examined. We analyzed the problem of the paratesticular localization paying particular attention to the role of surgery in dealing with paraaortic nodes. In the first study (RMS 79) the surgical exploration of retroperitoneal nodes was required: this procedure performed in 11 out of 14 patients affected by paratesticular RMS confirmed the negative data observed with diagnostic investigations. In RMS 88 study the sampling of retroperitoneal nodes was not required in cases with negative radiological findings but suggested in those cases with uncertain signs; two out of 8 patients underwent a laparotomy. In these two cases the results were negative. These 22 children were treated with an adjuvant chemotherapy after surgery and at present they show no evidence of disease.
Gamba
P G
PG
Cecchetto
G
G
Katende
M
M
Carli
M
M
Sotti
G
G
Guglielmi
M
M
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008197:Lymph Node Excision; D008297:Male; D009919:Orchiectomy; D012208:Rhabdomyosarcoma / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*