Nuclear magnetic resonance (NMR) analysis on the serum lipids of rabbits infected with Schistosoma japonicum: oxidative modifications of diene system in fatty chains.
Proton nuclear magnetic resonance (1H NMR) spectroscopy was used to characterize the oxidized products in the serum lipoprotein lipids (LPL) of rabbits infected with Schistosoma japonicum. The loss of bis-allylic and allylic methylenes proton peaks (2.7 and 2.0 p.p.m.) of unsaturated systems of the LPL and the appearance of the signals of the conjugated diene systems of hydroperoxide (5.43-6.45 p.p.m.) and epidioxide (2.45 p.p.m.) of the fatty chains of the serum demonstrated the lipids degradation associated with the Schistosoma infection.
Nishina
M
M
Department of Medical Zoology, Saitama Medical School, Japan.
Matsushita
K
K
Furuhata
T
T
Hori
E
E
Takahashi
M
M
Kato
K
K
Matsuda
H
H
D000818:Animals; D008055:Lipids / Q000097:blood* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D011817:Rabbits; D012554:Schistosomiasis japonica / Q000097:blood*
D008055:Lipids