title: Calbindin D-28K in the dopaminergic mesocortical projection of a monkey (Aotus trivirgatus).
abstract: Injections of fluorescent dyes were made in the prefrontal and motor cortex of owl monkeys and retrogradely labeled neurons in the mesencephalon were analyzed for tyrosine hydroxylase and calbindin-D28K immunostaining. Numbers of mesocortical dopaminergic neurons in the dorsal substantia nigra compacta and in the ventral tegmental area also contain calbindin-D28K. This cortically projecting calbindin-D28K containing subpopulation of the dopaminergic mesencephalic cells may be characterized by different electrophysiological properties and a lesser vulnerability to cell death.
authors.affiliation: Department of Psychology, Vanderbilt University, Nashville, TN.
authors.forename: P
authors.initials: P
authors.lastname: Gaspar
authors.forename: C W
authors.initials: CW
authors.lastname: Heizmann
authors.forename: J H
authors.initials: JH
authors.lastname: Kaas
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D001029:Aotus trivirgatus; D001933:Brain Stem / Q000033:anatomy & histology / Q000276:immunology; D064026:Calbindins; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000378:metabolism*; D004298:Dopamine / Q000502:physiology*; D004594:Electrophysiology; D005455:Fluorescent Antibody Technique; D005456:Fluorescent Dyes; D006651:Histocytochemistry; D008636:Mesencephalon / Q000033:anatomy & histology / Q000378:metabolism*; D009434:Neural Pathways / Q000033:anatomy & histology / Q000378:metabolism*; D064030:S100 Calcium Binding Protein G / Q000276:immunology / Q000378:metabolism*; D014446:Tyrosine 3-Monooxygenase / Q000276:immunology / Q000378:metabolism
chemical_list: D000911:Antibodies, Monoclonal; D064026:Calbindins; D005456:Fluorescent Dyes; D064030:S100 Calcium Binding Protein G; D014446:Tyrosine 3-Monooxygenase; D004298:Dopamine