title: Laparoscopy versus laparotomy for ovarian conservative surgery: a randomized trial in the rabbit model.
abstract: OBJECTIVE
  Our purpose was to compare postoperative adhesion formation and reproductive outcome after the same ovarian surgical procedure performed by laparoscopy or laparotomy by means of microsurgical techniques.
  
  
  METHODS
  Twenty-eight New Zealand White female rabbits were randomly assigned to laparotomy or laparoscopy for the same standardized surgical procedure: both ovaries were grasped with atraumatic forceps and longitudinally incised on the antimesenteric side from the cortex to the hilum with a microelectrode delivering a tissue power density of 66,666 W/cm. The rabbits were then mated, and 2 weeks later a second-look laparotomy was performed by a blinded observer for the evaluation of postoperative adhesions, number of corpora lutea in each ovary, number of embryos in the ipsilateral uterine horn, and nidation index for each side.
  
  
  RESULTS
  At second look no statistically significant differences were found in postoperative adhesion formation, number of corpora lutea, number of embryos, and nidation index between the laparoscopy and the laparotomy groups.
  
  
  CONCLUSIONS
  Laparoscopy or laparotomy for ovarian conservative surgery do not appear significantly different in postoperative adhesion formation and reproductive outcome in the rabbit model.
authors.affiliation: Department of Obstetrics and Gynecology, Universitá Cattolica del Sacro Cuore, Rome, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Marana
authors.forename: A A
authors.initials: AA
authors.lastname: Luciano
authors.forename: L
authors.initials: L
authors.lastname: Muzii
authors.forename: V E
authors.initials: VE
authors.lastname: Marendino
authors.forename: S
authors.initials: S
authors.lastname: Mancuso
mesh_terms: D000818:Animals; D010064:Embryo Implantation; D005260:Female; D010535:Laparoscopy; D007813:Laparotomy; D008866:Microsurgery; D010049:Ovarian Diseases / Q000209:etiology / Q000503:physiopathology; D010053:Ovary / Q000601:surgery*; D011183:Postoperative Complications / Q000503:physiopathology; D011247:Pregnancy; D011446:Prospective Studies; D011817:Rabbits; D011897:Random Allocation; D012098:Reproduction; D000267:Tissue Adhesions / Q000209:etiology / Q000503:physiopathology