title: On the function of histamine in the central nervous system of arthropods.
abstract: Histamine is localized in the CNS of many invertebrate taxa by various methods. It is described to act as a neurotransmitter, neuromodulator, and neurohormone. Because of its distribution throughout these taxa it is tempting to forward the following hypothesis: Histamine acts as a neuroactive substance in all invertebrates. Its function as a transmitter of photoreceptors is restricted to arthropods. A special system of six large histamine-immunoreactive neurons exists exclusively in arachnids.
authors.affiliation: Institut für Zoologie, Universität Wien, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Schmid
authors.forename: M
authors.initials: M
authors.lastname: Duncker
mesh_terms: D000818:Animals; D001181:Arthropods / Q000502:physiology*; D006632:Histamine / Q000032:analysis / Q000502:physiology*; D007150:Immunohistochemistry; D009420:Nervous System / Q000166:cytology; D009424:Nervous System Physiological Phenomena; D018377:Neurotransmitter Agents / Q000032:analysis / Q000502:physiology; D010786:Photoreceptor Cells / Q000166:cytology / Q000502:physiology; D014785:Vision, Ocular
chemical_list: D018377:Neurotransmitter Agents; D006632:Histamine