title: The calf superoxide dismutase receptor of rat hepatocytes.
abstract: The presence of a specific SOD surface membrane receptor in rat hepatocyte cells was investigated using ligand blot analysis of the SOD receptor with 125I-SOD, and binding studies with iodinated and fluorescinated SOD. A specific SOD receptor with a molecular weight of about 320 kDa was identified. We suggest that the modulatory role of SOD on HMG-CoA reductase is exerted through this specific receptor.
authors.affiliation: Istituto di Scienze Fisiologiche Umane, Facoltà di Medicina e Chirurgia dell'Università di Napoli Federico II, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Mondola
authors.forename: M
authors.initials: M
authors.lastname: Santillo
authors.forename: F
authors.initials: F
authors.lastname: Santangelo
authors.forename: C
authors.initials: C
authors.lastname: Garbi
authors.forename: A
authors.initials: A
authors.lastname: Daniele
mesh_terms: D000818:Animals; D002417:Cattle; D002460:Cell Line; D008099:Liver / Q000166:cytology / Q000201:enzymology / Q000378:metabolism*; D008856:Microscopy, Fluorescence; D011869:Radioligand Assay; D051381:Rats; D011956:Receptors, Cell Surface / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D011956:Receptors, Cell Surface; D013482:Superoxide Dismutase