Oxidation of methyl fluoride and dimethyl ether by ammonia monooxygenase in Nitrosomonas europaea.
Methyl fluoride and dimethyl ether were previously identified as inhibitors of ammonia oxidation and N2O production in autotrophic nitrifying bacteria. We demonstrate that methyl fluoride and dimethyl ether are substrates for ammonia monooxygenase and are converted to formaldehyde and a mixture of methanol and formaldehyde, respectively.
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Laboratory for Nitrogen Fixation Research, Oregon State University, Corvallis 97331-2902.
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D005557:Formaldehyde / Q000378:metabolism; D006845:Hydrocarbons, Fluorinated / Q000378:metabolism* / Q000494:pharmacology; D000432:Methanol / Q000378:metabolism; D008738:Methyl Ethers / Q000378:metabolism* / Q000494:pharmacology; D009606:Nitrosomonas / Q000201:enzymology*; D010084:Oxidation-Reduction / Q000187:drug effects; D010088:Oxidoreductases / Q000378:metabolism*
D006845:Hydrocarbons, Fluorinated; D008738:Methyl Ethers; D005557:Formaldehyde; C029999:fluoromethane; C033413:dimethyl ether; D010088:Oxidoreductases; C045582:ammonia monooxygenase; D000432:Methanol