[Changes in the mechanical integration of transitional epithelial cells and in the immune status of patients with bladder tumors].
Mutual adhesiveness of urothelial tissue cells have been studied in healthy donors and patients with benign and malignant bladder tumors. The decreased mutual adhesiveness has been shown not only for tumors, but for surrounding urothelial tissue as well. Urothelial tissue integration, T-cell immunity and parameters of leukocyte integrins were affected most of all in bladder tumor stage T2 and T3. Basing on these findings, the authors recommend conservative therapy only in superficial bladder cancer.
Bocharova
O A
OA
Serebriakova
R V
RV
Golubeva
V A
VA
Figurin
K M
KM
Bukharkin
B V
BV
Bodrova
N B
NB
Matveev
B P
BP
Baryshnikov
A Iu
AIu
D015703:Antigens, CD / Q000097:blood; D001782:Blood Donors; D002295:Carcinoma, Transitional Cell / Q000276:immunology* / Q000473:pathology*; D002448:Cell Adhesion; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010212:Papilloma / Q000276:immunology* / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000276:immunology / Q000473:pathology; D001743:Urinary Bladder / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000276:immunology* / Q000473:pathology*
D015703:Antigens, CD
Izmenenie mekhanicheskoĭ integratsii kletok perekhodnogo épiteliia i immunnogo statusa bol'nykh s opukholiami mochevogo puzyria.