title: Recurrences after endoscopic management of early (T1) glottic carcinoma.
abstract: From 1976 to 1986, 106 patients with early glottic carcinoma were managed endoscopically at our institution. Twenty-four (23%) patients required retreatment of the larynx for local recurrences or new primary lesions after initial endoscopic management. The probability of remaining free of local recurrence 3 years after primary surgery was estimated to be 0.87 and, after 5 years, it was 0.81. Of the 24 patients who required re-treatment of their larynx, 10 did so beyond 3 years, indicating a new second primary. In 1 patient who required retreatment within 3 years, a new primary developed on the opposite cord. Therefore, true local recurrences developed in 13 patients (12.3%); 3 of these patients (2.8%) ultimately required laryngectomy and 3 are dead (2.8%) with disease.
authors.affiliation: Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 55905.
authors.forename: J V
authors.initials: JV
authors.lastname: Thomas
authors.forename: K D
authors.initials: KD
authors.lastname: Olsen
authors.forename: H B
authors.initials: HB
authors.lastname: Neel
authors.forename: L W
authors.initials: LW
authors.lastname: DeSanto
authors.forename: V J
authors.initials: VJ
authors.lastname: Suman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000473:pathology / Q000601:surgery*; D002423:Cause of Death; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D005931:Glottis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000473:pathology; D011336:Probability; D012086:Reoperation; D012307:Risk Factors; D015996:Survival Rate; D014827:Vocal Cords / Q000601:surgery