Predictive testing of radiosensitivity in non-small cell carcinoma of the lung.
The paper reviews the prognostic factors which influence the radiosensitivity of non-small cell lung cancer. The clonogenic cell numbers, hypoxic fraction, tumour cell kinetics and inherent radiosensitivity are considered. In the future the measurement of these factors may play an important role in decision making as to the best management for patients with non-small cell lung cancer.
Saunders
M I
MI
Marie Curie Research Wing for Oncology, Mount Vernon Centre for Cancer Treatment, Mount Vernon Hospital, Northwood, Middlesex, UK.
D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D015687:Cell Hypoxia; D003599:Cytoskeleton / Q000648:ultrastructure; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000532:radiotherapy; D006729:Hormones, Ectopic / Q000032:analysis; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000528:radiation effects; D010641:Phenotype; D011379:Prognosis; D011836:Radiation Tolerance; D014410:Tumor Stem Cell Assay
D006729:Hormones, Ectopic