The role of magnetic resonance for assessing radiation-induced lung damage.
OBJECTIVE
To investigate the potential role of Magnetic Resonance for assessing radiation-Induced lung damage.


METHODS
T1 and T2 relaxation times were measured for lungs excised from Sprague-Dawley rats at various times following thoracic irradiation.


RESULTS
Although on average a 10% increase was observed in the T2 relaxation times between 30 and 80 days after irradiation, this is too small to affect image contrast.


CONCLUSIONS
The results indicate that relaxation measurements are unlikely to yield new information to characterize changes in lung tissue caused by radiation.
Newcomb
C H
CH
Ontario Cancer Institute/Princess Margaret Hospital, Toronto, Canada.
Van Dyk
J
J
Hill
R P
RP
D000818:Animals; D005260:Female; D008168:Lung / Q000473:pathology / Q000528:radiation effects*; D008171:Lung Diseases / Q000175:diagnosis* / Q000209:etiology; D008279:Magnetic Resonance Imaging; D015999:Multivariate Analysis; D011833:Radiation Injuries, Experimental / Q000175:diagnosis* / Q000209:etiology; D051381:Rats; D017207:Rats, Sprague-Dawley