title: Serological definition of bovine MHC class II polymorphism in Holstein-Friesians.
abstract: Analysis of the reaction patterns of 57 putative class II MHC alloantisera revealed 18 B-cell serum clusters, named Ds01-Ds18. These clusters were grouped together in such a manner that 17 provisional serological class II haplotypes were defined. Segregation in half-sib families of these class II haplotypes with serologically defined class I and 1D-IEF defined DRB3 types indicated that the 18 clusters identify class II polymorphisms in cattle and can be considered as local specificities.
authors.affiliation: Department of Animal Husbandry, Agricultural University, Wageningen, The Netherlands.
authors.forename: P R
authors.initials: PR
authors.lastname: Nilsson
authors.forename: G M
authors.initials: GM
authors.lastname: Schreuder
authors.forename: J
authors.initials: J
authors.lastname: D'Amaro
authors.forename: I
authors.initials: I
authors.lastname: Joosten
authors.forename: R C
authors.initials: RC
authors.lastname: Buis
authors.forename: C J
authors.initials: CJ
authors.lastname: Davies
authors.forename: J J
authors.initials: JJ
authors.lastname: van der Poel
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics* / Q000276:immunology*; D005260:Female; D006239:Haplotypes; D015395:Histocompatibility Antigens Class I / Q000235:genetics / Q000276:immunology; D000949:Histocompatibility Antigens Class II / Q000235:genetics* / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology; D007525:Isoelectric Focusing / Q000662:veterinary; D008214:Lymphocytes / Q000276:immunology; D011110:Polymorphism, Genetic / Q000276:immunology*
chemical_list: D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II; D007106:Immune Sera