title: Histiocytosis X revealed by complex anal fistula.
abstract: A very unusual clinical case of histiocytosis X in a young girl with no unusual medical history, is presented. The patient presented with chronic suppuration of the groin and complex anal fistulae and multiple recurrent abscesses, despite surgical treatment (abscess drainage, terminal colostomy). Intestinal and immunologic evaluation were normal. Only histology made the diagnosis. Chemotherapy (vinblastine) resulted in healing and the colostomy was closed.
authors.affiliation: Service de Chirurgie Viscérale Pédiatrique, Hôpital Trousseau, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Grapin
authors.forename: G
authors.initials: G
authors.lastname: Audry
authors.forename: P
authors.initials: P
authors.lastname: Josset
authors.forename: C
authors.initials: C
authors.lastname: Patte
authors.forename: E
authors.initials: E
authors.lastname: Sorrel Dejerine
authors.forename: M
authors.initials: M
authors.lastname: Gruner
mesh_terms: D000293:Adolescent; D001003:Anal Canal / Q000473:pathology; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D012003:Rectal Fistula / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D014747:Vinblastine