title: [Intra-arterial regional chemotherapy in the combined treatment of stage-III cancer of the stomach].
abstract: The report discusses a method of long-term catheterization of the celiac artery by lumbo-transaortal access. Intraarterial regional chemotherapy with 5-fluorouracil was administered to 56 cases of gastric cancer, stage III, before and after surgery. A significant drop in postoperative complication rate from 47.8 +/- 6% after surgery to 16.0 +/- 4% after combination treatment was recorded. During two years after operation, metastases and recurrences were registered in II out of 52 patients receiving intraarterial chemotherapy (21. +/- 5%), as compared with 34 out of 58 (58.6 +/- 6%) in controls without chemotherapy.
authors.forename: B N
authors.initials: BN
authors.lastname: Zyrianov
authors.forename: N A
authors.initials: NA
authors.lastname: Makarkin
authors.forename: V I
authors.initials: VI
authors.lastname: Tikhonov
authors.forename: S A
authors.initials: SA
authors.lastname: Tuzikov
mesh_terms: D002408:Catheters, Indwelling; D002445:Celiac Artery; D017024:Chemotherapy, Adjuvant; D010478:Chemotherapy, Cancer, Regional Perfusion; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D007261:Infusions, Intra-Arterial; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D005472:Fluorouracil
vernacular_title: Vnutriarterial'naia regionarnaia khimioterapiia v kombinirovannom lechenii raka zheludka III stadii.