Desensitization to sulphasalazine in patients with arthritis.
Desensitization to sulphasalazine was successful in 16 of 21 (76%) arthritic patients who previously had skin rash from sulphasalazine (success rate: 8 of 13, or 62%) or sulphonamide (success rate: 8 out of 8 patients). Desensitization to sulphasalazine is a simple outpatient procedure which allows many subjects who develop a skin rash to sulphonamide or sulphasalazine to start or continue sulphasalazine treatment.
Koski
J M
JM
Mikkeli Central Hospital, Finland.
D000328:Adult; D000368:Aged; D001168:Arthritis / Q000188:drug therapy* / Q000276:immunology; D003888:Desensitization, Immunologic; D003875:Drug Eruptions / Q000209:etiology / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000188:drug therapy; D012460:Sulfasalazine / Q000009:adverse effects / Q000276:immunology* / Q000627:therapeutic use*; D013449:Sulfonamides / Q000009:adverse effects / Q000276:immunology / Q000627:therapeutic use
D013449:Sulfonamides; D012460:Sulfasalazine