title: Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite.
authors.affiliation: Department of Chemical Biology and Pharmacognsoy, College of Pharmacy, Rutgers, State University of New Jersey, Piscataway 08855.
authors.forename: A H
authors.initials: AH
authors.lastname: Conney
authors.forename: R L
authors.initials: RL
authors.lastname: Chang
authors.forename: D M
authors.initials: DM
authors.lastname: Jerina
authors.forename: S J
authors.initials: SJ
authors.lastname: Wei
mesh_terms: D015123:7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D001483:Base Sequence; D001564:Benzo(a)pyrene / Q000378:metabolism* / Q000633:toxicity; D001711:Biotransformation; D002460:Cell Line; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008969:Molecular Sequence Data; D016296:Mutagenesis; D009153:Mutagens
chemical_list: D009153:Mutagens; D001564:Benzo(a)pyrene; D015123:7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide