Severe flares of acne following isotretinoin: large closed comedones (macrocomedones) are a risk factor.
Bottomley
W W
WW
Cunliffe
W J
WJ
D000152:Acne Vulgaris / Q000188:drug therapy* / Q000473:pathology; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects* / Q000627:therapeutic use; D012307:Risk Factors
D015474:Isotretinoin