title: Intracranial MR angiography: comparison of single-volume three-dimensional time-of-flight and multiple overlapping thin slab acquisition techniques.
abstract: OBJECTIVE
  Time-of-flight (TOF) MR angiography has continued to evolve during the past few years. Signal loss due to flow saturation is a major problem of single-volume (slab) three-dimensional (3D) TOF technique. A multislab 3D TOF method, multiple overlapping thin slab acquisition (MOTSA), shows decreased sensitivity to the effects of flow saturation and therefore should result in better images.
  
  
  METHODS
  To evaluate the difference between MOTSA and the traditional single-volume 3D TOF techniques, we performed sequential, location-matched studies in 17 prospectively chosen patients with intracranial vascular abnormalities. All MOTSA and 3D TOF images were obtained after cut-film or 1024 digital angiography.
  
  
  RESULTS
  According to specific criteria, abnormalities were better visualized with the MOTSA technique than with the single-volume 3D TOF technique. The difference was most marked in patients with more complex vascular abnormalities.
  
  
  CONCLUSIONS
  We conclude that MOTSA is better than single-volume 3D TOF for showing intracranial abnormalities. The major advantage of MOTSA is decreased sensitivity to flow saturation.
authors.affiliation: Department of Radiology, University of Utah Medical Center, Salt Lake City 84132.
authors.forename: W L
authors.initials: WL
authors.lastname: Davis
authors.forename: D D
authors.initials: DD
authors.lastname: Blatter
authors.forename: H R
authors.initials: HR
authors.lastname: Harnsberger
authors.forename: D L
authors.initials: DL
authors.lastname: Parker
mesh_terms: D001921:Brain / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis* / Q000453:epidemiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity