title: Intra-articular radiation treatment of rheumatoid synovitis of the ankle with dysprosium-165 ferric hydroxide macroaggregates.
abstract: Intra-articular radiation treatment using dysprosium-165 ferric hydroxide macroaggregate has been performed on eight patients with refractory synovitis of the ankle. Seventy-five percent (six patients) responded well to the treatment, and there were no complications from the injection. Although ankle synovectomy is not often indicated, those patients with rheumatoid synovitis without significant joint destruction respond favorably to radiation treatment.
authors.affiliation: Department of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
authors.forename: C L
authors.initials: CL
authors.lastname: Barnes
authors.forename: S
authors.initials: S
authors.lastname: Shortkroff
authors.forename: M
authors.initials: M
authors.lastname: Wilson
authors.forename: C B
authors.initials: CB
authors.lastname: Sledge
mesh_terms: D000328:Adult; D000368:Aged; D000843:Ankle Joint; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000532:radiotherapy*; D004419:Dysprosium / Q000627:therapeutic use*; D005260:Female; D005290:Ferric Compounds; D006801:Humans; D008297:Male; D008875:Middle Aged; D011868:Radioisotopes / Q000627:therapeutic use*; D013585:Synovitis / Q000209:etiology / Q000532:radiotherapy*; D016896:Treatment Outcome
chemical_list: D005290:Ferric Compounds; D011868:Radioisotopes; D004419:Dysprosium; C021024:ferric hydroxide