title: Neonatal portal vein thrombosis successfully treated by regional streptokinase infusion.
abstract: We report a case of portal vein thrombosis (PVT) in a term neonate following an exchange transfusion through an umbilical vein catheter which was left in situ for 16 h after the transfusion. The baby made a complete recovery after successful thrombolysis with regional streptokinase infusion. To our knowledge, this is the first reported case of a PVT following an indwelling portal venous catheter left in situ with complete resolution following thrombolysis with regional streptokinase infusion.
authors.affiliation: Section of Neonatology, Women's Hospital, Winnipeg, Manitoba, Canada.
authors.forename: V K
authors.initials: VK
authors.lastname: Rehan
authors.forename: C M
authors.initials: CM
authors.lastname: Cronin
authors.forename: J M
authors.initials: JM
authors.lastname: Bowman
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007261:Infusions, Intra-Arterial; D008297:Male; D011169:Portal Vein; D013300:Streptokinase / Q000008:administration & dosage / Q000627:therapeutic use*; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy*
chemical_list: D013300:Streptokinase