[Cholesterol levels in lipoproteins and various intake of amino acids in an experiment].
In the conditions of physiological nutrient content and variable amino-acid mixtures made of casein K, gluten G and KG combination (1:1, standard diet), the 10-week effect of amino acids (until the age of 105 days, end of maturation stage) was investigated in growing rats with respect to protein utilization (net protein ratio) and to the values of lipid parameters at the end of the experiment (cholesterol, triacylglycerols, atherogenic indexes, cholesterol distribution into lipoprotein classes). A significant decrease in NPR for gluten, an insignificant decrease for casein in the growth period are related to the amino acid score of limiting amino acids--they determine rate of proteosynthesis and potential biological value--amount percentage of amino acids of the given diet for plastic processes of proteins (AS for KG 69, for K 67, for G 28; BHp for KG 83.1, for K 70.0, for G 54.1). Since day 105 amino acid utilization is balanced in all groups, hence it does not depend upon the quality of aminograms (lower rate of proteosynthesis in comparison with the growth period, for which the values of limiting amino acids are sufficiently high). Significantly decreased values of cholesterolemia and triacylglycerolemia for gluten food, insignificantly higher values for casein food, are in direct correlations with the values of Lys/Arg, Met/Arg, Met, Lys, and in indirect correlations with Arg and Arg+Glu+Gly. Distribution of HDL-cholesterol as a cholesterol percentage in HD lipoproteins is higher by 8.7% for gluten and all atherogenic indexes are significantly decreased in contrast to casein food, in which a slight decrease in HDL-cholesterol and insignificantly higher atherogenic indexes were recorded.
Krajcovicová-Kudlácková
M
M
Výskumný śtav výzivy, Bratislava.
Bobek
P
P
D000596:Amino Acids / Q000008:administration & dosage* / Q000378:metabolism; D000818:Animals; D002364:Caseins / Q000008:administration & dosage; D002784:Cholesterol / Q000032:analysis*; D005983:Glutens / Q000008:administration & dosage; D008074:Lipoproteins / Q000737:chemistry*; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D000596:Amino Acids; D002364:Caseins; D008074:Lipoproteins; D005983:Glutens; D002784:Cholesterol
Koncentrácia cholesterolu v lipoproteínoch a rôzny príjem aminokyselín v experimente.