Dural sinus thrombosis and venous infarction associated with antiphospholipid antibodies: MR findings.
OBJECTIVE
Our goal was to describe the neuroradiologic findings in hemorrhagic venous infarction related to a hypercoagulable state caused by antiphospholipid antibodies (aPA).


METHODS
Magnetic resonance imaging was performed on two patients with superior sagittal thrombosis related to the presence of aPA.


RESULTS
A parenchymal region of hyperintense signal due to hemorrhagic venous infarction was demonstrated in both patients, along with abnormal signal within the thrombosed superior sagittal sinus.


CONCLUSIONS
Hemorrhagic venous infarction may result from the hypercoagulable state related to aPA. The presence of these antibodies should be considered in the setting of otherwise unexplained dural sinus thrombosis and/or venous infarction.
Provenzale
J M
JM
Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
Loganbill
H A
HA
D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000276:immunology; D002544:Cerebral Infarction / Q000175:diagnosis* / Q000276:immunology; D002550:Cerebral Veins / Q000276:immunology / Q000473:pathology*; D004388:Dura Mater / Q000276:immunology / Q000473:pathology*; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000032:analysis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012851:Sinus Thrombosis, Intracranial / Q000175:diagnosis* / Q000276:immunology
D017152:Antibodies, Antiphospholipid; D016682:Lupus Coagulation Inhibitor