title: [Microcirculatory disorders of the systemic circulation and the myocardium in congenital heart defects with a left to right shunt].
abstract: Microcirculatory bed of the epi- and pericardium, parietal pleura, bulbar conjunctiva is studied in congenital heart defects. The alterations of the microvessels were similar in all above organs. The following conclusions are made: a) the reduction of microvessels manifests as capillary failure of the myocardium resulting in cardiomyocyte destruction and development of cardiosclerosis, b) myocardial alterations result in heart failure and enhancement of systemic microhemocirculation, c) irreversible pathological processes can be prevented by early surgery only.
authors.forename: T N
authors.initials: TN
authors.lastname: Nikolaeva
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003326:Coronary Circulation / Q000502:physiology*; D006330:Heart Defects, Congenital / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D008833:Microcirculation / Q000502:physiology; D012598:Sclerosis
vernacular_title: Patologiia mikrotsirkuliatornogo rusla bol'shogo kruga krovoobrashcheniia i miokarda pri vrozhdennykh porokakh serdtsa s levopravym shuntom.