title: Gliosarcoma. Case report with immunohistochemical study.
abstract: A typical case of gliosarcoma in a 74 year-old woman is reported. The exact origin of sarcomatous areas of this tumor has been a matter of debate. Our immunohistochemical findings, using a panel of antibodies (GFAP), vimentin, keratins, F-VIII related antigen, muscle specific actin, KP-1 and HMB-45), support its undifferentiated nature. The literature concerning this topic is reviewed and briefly discussed.
authors.affiliation: Dept de Anatomía Patológica, Hospital Civil, Bilbao, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Eizaguirre
authors.forename: J M
authors.initials: JM
authors.lastname: Elizalde
authors.forename: L J
authors.initials: LJ
authors.lastname: Martinez
authors.forename: C
authors.initials: C
authors.lastname: Ereño
authors.forename: J I
authors.initials: JI
authors.lastname: Lopez
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D018316:Gliosarcoma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D013702:Temporal Lobe