[The clinico-immunological effects of leukinferon in the treatment of patients with acute suppurative pyelonephritis].
The effect of leukinferon (LKF) administration to 20 patients with acute renal inflammation was evaluated versus the effect of basic therapy given to 19 matched patients. A short course of LKF (3 injections) promoted more rapid discontinuation of the fever, recovery of satisfactory general condition, healing of postoperative wounds. Immunologically, the test subjects exhibited a rise in the previously low levels of lymphocytes, B-cells, T-helpers, IgA and IgG. The proportion of T-lymphocyte subpopulations improved and the activity of EC-cells enhanced. It is thought valid to use LKF in acute renal inflammation and surgical urological affections.
Vozianov
A S
AS
Kuznetsova
V P
VP
Driianskaia
V E
VE
Pasechnikov
S P
SP
Ozvinchuk
I I
II
Musiĭ
M Ia
MIa
Fedorchuk
G V
GV
Beliaev
D L
DL
Dranik
G N
GN
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000917:Antibody Formation / Q000187:drug effects; D003131:Combined Modality Therapy; D016207:Cytokines / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007370:Interferon Type I / Q000627:therapeutic use*; D008297:Male; D011182:Postoperative Care; D011704:Pyelonephritis / Q000276:immunology* / Q000628:therapy*
D000276:Adjuvants, Immunologic; D016207:Cytokines; D004338:Drug Combinations; D007370:Interferon Type I; C062252:leukinferon
Kliniko-immunologicheskie éffekty leĭkinferona pri lechenii bol'nykh ostrym gnoĭnym pielonefritom.