title: The tuberculin test.
abstract: Tuberculin tests in general use today rely on the response to intradermal injections of tuberculin with assessment of the injection site for swelling at 72 hours post injection. Estimates of the sensitivity of tuberculin tests range from 68-95% while specificity is estimated to be 96-99%. The sensitivity of the test is affected by the potency and dose of tuberculin administered, the interval post-infection, desensitisation, deliberate interference, post-partum immunosuppression and observer variation. Specificity is influenced by sensitisation as a result of exposure to M. avium, M. paratuberculosis and environmental mycobacteria and by skin tuberculosis.
authors.affiliation: Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Ireland.
authors.forename: M L
authors.initials: ML
authors.lastname: Monaghan
authors.forename: M L
authors.initials: ML
authors.lastname: Doherty
authors.forename: J D
authors.initials: JD
authors.lastname: Collins
authors.forename: J F
authors.initials: JF
authors.lastname: Kazda
authors.forename: P J
authors.initials: PJ
authors.lastname: Quinn
mesh_terms: D000818:Animals; D002417:Cattle; D005188:False Negative Reactions; D005189:False Positive Reactions; D012680:Sensitivity and Specificity; D014373:Tuberculin / Q000737:chemistry / Q000276:immunology / Q000302:isolation & purification; D014374:Tuberculin Test / Q000592:standards / Q000662:veterinary*; D014380:Tuberculosis, Bovine / Q000175:diagnosis*
chemical_list: D014373:Tuberculin