title: Further bioactive cembranolide diterpenes from the gorgonian Eunicea succinea.
abstract: In our continuing comparative study of the diterpenoid content of the Caribbean gorgonian Eunicea succinea from different locations around Puerto Rico, three new cembranolide diterpenes, named 12,13-bisepieupalmerin acetate [5], 12-epi-eupalmerin acetate [6], and succinolide [7], were isolated from specimens collected off the east coast of Puerto Rico. The structure of each compound was deduced spectroscopically, and those of 5 and 7 were confirmed by chemical correlation with compounds of known structure.
authors.affiliation: Department of Chemistry, University of Puerto Rico, Río Piedras 00931-3346.
authors.forename: A D
authors.initials: AD
authors.lastname: Rodríguez
authors.forename: H
authors.initials: H
authors.lastname: Dhasmana
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D003063:Cnidaria / Q000737:chemistry*; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D014407:Tumor Cells, Cultured / Q000187:drug effects* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D004224:Diterpenes