title: Comparative study of collagen and expanded polytetrafluoroethylene membranes in the treatment of human class II furcation defects.
abstract: The purpose of this study was to compare the changes in clinical attachment when either a non-resorbable ePTFE membrane or an absorbable collagen membrane was used as a barrier during surgical treatment of class II molar furcation defects. Thirteen patients, mean age 43.2 years, with two comparable class II molar defects were treated using a split mouth design. Pre-surgical standardized probings were made using an automated probe at a constant force of 25 grams. Four to 6 weeks after initial therapy, the furcations were surgically debrided, the membranes placed to occlude separate furcation defects in each patient, and the sites closed. The ePTFE membrane was removed 6 weeks after placement. Six months postsurgery, the clinical measurements were repeated. Student t test was used to compare the results. There were no significant differences in the mean initial measurements between the treatment groups. The mean decrease in vertical probing depth was 1.40 +/- 1.68 mm for the collagen treated sites and 1.07 +/- 0.81 mm for the ePTFE treated sites. The decrease in horizontal probing depth was 1.49 +/- 1.97 mm for the collagen treated sites and 0.79 +/- 2.16 mm for the ePTFE treated sites. No significant differences were found between any of the clinical parameters measured. Based on the results of this short-term clinical study, the absorbable collagen membrane was statistically equivalent to the non-resorbable ePTFE membrane in the clinical resolution of class II furcation defects.
authors.affiliation: Periodontics Department, Naval Dental School, National Naval Dental Center, Bethesda, MD.
authors.forename: B S
authors.initials: BS
authors.lastname: Black
authors.forename: M E
authors.initials: ME
authors.lastname: Gher
authors.forename: J B
authors.initials: JB
authors.lastname: Sandifer
authors.forename: S E
authors.initials: SE
authors.lastname: Fucini
authors.forename: A C
authors.initials: AC
authors.lastname: Richardson
mesh_terms: D000042:Absorption; D000328:Adult; D000368:Aged; D001672:Biocompatible Materials / Q000737:chemistry; D003094:Collagen / Q000009:adverse effects / Q000737:chemistry; D005260:Female; D017823:Furcation Defects / Q000145:classification / Q000473:pathology / Q000601:surgery*; D005889:Gingival Recession / Q000473:pathology / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D017622:Periodontal Attachment Loss / Q000473:pathology / Q000601:surgery; D010514:Periodontal Pocket / Q000473:pathology / Q000601:surgery; D011138:Polytetrafluoroethylene / Q000009:adverse effects; D013529:Surgical Wound Dehiscence / Q000209:etiology
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D003094:Collagen