title: RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes.
abstract: Plant disease resistance genes function is highly specific pathogen recognition pathways. PRS2 is a resistance gene of Arabidopsis thaliana that confers resistance against Pseudomonas syringae bacteria that express avirulence gene avrRpt2. RPS2 was isolated by the use of a positional cloning strategy. The derived amino acid sequence of RPS2 contains leucine-rich repeat, membrane-spanning, leucine zipper, and P loop domains. The function of the RPS2 gene product in defense signal transduction is postulated to involve nucleotide triphosphate binding and protein-protein interactions and may also involve the reception of an elicitor produced by the avirulent pathogen.
authors.affiliation: Department of Plant Biology, University of California, Berkeley 94720.
authors.forename: A F
authors.initials: AF
authors.lastname: Bent
authors.forename: B N
authors.initials: BN
authors.lastname: Kunkel
authors.forename: D
authors.initials: D
authors.lastname: Dahlbeck
authors.forename: K L
authors.initials: KL
authors.lastname: Brown
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
authors.forename: J
authors.initials: J
authors.lastname: Giraudat
authors.forename: J
authors.initials: J
authors.lastname: Leung
authors.forename: B J
authors.initials: BJ
authors.lastname: Staskawicz
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics* / Q000382:microbiology; D029681:Arabidopsis Proteins; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D003360:Cosmids; D018076:DNA, Complementary / Q000235:genetics; D005798:Genes, Bacterial; D017343:Genes, Plant; D016350:Leucine Zippers; D008969:Molecular Sequence Data; D010641:Phenotype; D010935:Plant Diseases / Q000235:genetics*; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics*; D011549:Pseudomonas / Q000235:genetics / Q000472:pathogenicity; D015398:Signal Transduction; D014774:Virulence
chemical_list: D029681:Arabidopsis Proteins; D018076:DNA, Complementary; D010940:Plant Proteins; C089426:RPS2 protein, Arabidopsis