title: Obstructive sleep apnea. Warding off the sometimes dire consequences.
abstract: Obstructive sleep apnea (occlusion of the upper airway despite continued respiratory muscle activity) is accompanied by increased morbidity and mortality from cardiovascular and cerebrovascular disease. Daytime sleepiness due to the disorder may also be a factor in a higher incidence of automobile accidents in these patients. An overnight polysomnogram is used to confirm the diagnosis and assess severity of physiologic disturbances. Initially, simple measures, such as avoidance of alcohol and sedatives before bedtime and sleeping on the side rather than the back, may be tried. Nasal continuous positive airway pressure is considered first-line therapy, and compliance can be improved by education and counseling of the patient. Uvulopalatopharyngoplasty is beneficial in only 50% of patients. Tracheostomy gives the most consistent long-term benefit but is accompanied by significant emotional morbidity.
authors.affiliation: Department of pulmonary and critical care medicine, Cleveland Clinic Foundation.
authors.forename: L S
authors.initials: LS
authors.lastname: Aboussouan
authors.forename: J A
authors.initials: JA
authors.lastname: Golish
authors.forename: B G
authors.initials: BG
authors.lastname: Wood
mesh_terms: D006801:Humans; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000628:therapy