Biology of GPI anchors and pathogenesis of paroxysmal nocturnal hemoglobinuria.
Recently, a number of leading scientists gathered in Hanover, Germany, to discuss glycosylphosphatidylinositol (GPI)-anchor structures. Here, Jörg Schubert and colleagues report on this highly interesting field.
Schubert
J
J
Dept of Immunology and Transfusion Medicine, Hanover Medical School, Germany.
Ostendorf
T
T
Schmidt
R E
RE
D000818:Animals; D017261:Glycosylphosphatidylinositols / Q000172:deficiency / Q000502:physiology*; D006457:Hemoglobinuria, Paroxysmal / Q000209:etiology*; D006801:Humans; D008213:Lymphocyte Activation / Q000502:physiology; D008565:Membrane Proteins / Q000235:genetics; D013601:T-Lymphocytes / Q000276:immunology
D017261:Glycosylphosphatidylinositols; D008565:Membrane Proteins; C080086:phosphatidylinositol glycan-class A protein