Clinical application of end-systolic pressure-volume relation.
On the basis of a mathematical formalism derived in previous studies, properties of the end-systolic pressure-volume (P-V) relation were analyzed to define indexes that can characterize a normal or failing left ventricle. Careful analysis of different areas under the P-V line can lead to new indexes that describe the performance of the left ventricle. The possibility to distinguish between normal, mildly depressed, or severely depressed left ventricles based on P-V relation is discussed. Implementation of the results for routine clinical work is examined.
Shoucri
R M
RM
Department of Mathematics and Computer Science, Royal Military College of Canada, Kingston, Ontario.
D000328:Adult; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D002303:Cardiac Output, Low / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008955:Models, Cardiovascular; D013318:Stroke Volume; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*