title: Risk of testicular cancer after vasectomy: cohort study of over 73,000 men.
abstract: OBJECTIVE
  To confirm or refute reports that vasectomy may increase the risk of cancers of the testis and prostate.
  
  
  METHODS
  Computerised record linkage study of cohort of men with vasectomy and comparison of cancer rates with those in the whole Danish population; manual check of all records of patients with testicular and prostate cancer diagnosed within the first year of follow up.
  
  
  METHODS
  Denmark 1977-89.
  
  
  METHODS
  Cohort of 73,917 men identified in hospital discharge and pathology registers as having had a vasectomy for any reason during 1977-89.
  
  
  METHODS
  Observed incidences of testicular, prostate, and other cancers up to the end of 1989.
  
  
  RESULTS
  The overall pattern of cancer incidence in the study cohort was similar to that expected nationally. No increased incidence in testicular cancer was observed (70 cases; standardised morbidity ratio 1.01 (95% confidence interval 0.79 to 1.28)). The incidence during the first year of follow up was also close to that expected (nine cases; standardised morbidity ratio 0.80 (0.36 to 1.51)). The incidence of prostate cancer was not increased (165 cases; standardised morbidity ratio 0.98 (0.84 to 1.14)).
  
  
  CONCLUSIONS
  The incidence of testicular cancer in men with vasectomy is no higher than in other men. Vasectomy does not cause testicular cancer and does not accelerate the growth or diagnosis of pre-existing testicular neoplasms. Data concerning a causal relation between vasectomy and prostate cancer were inconclusive.
authors.affiliation: Danish Cancer Society, Copenhagen.
authors.forename: H
authors.initials: H
authors.lastname: Møller
authors.forename: L B
authors.initials: LB
authors.lastname: Knudsen
authors.forename: E
authors.initials: E
authors.lastname: Lynge
mesh_terms: D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D003718:Denmark / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D009369:Neoplasms / Q000473:pathology; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000209:etiology; D012307:Risk Factors; D013736:Testicular Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D014659:Vasectomy / Q000009:adverse effects*