title: Small (< or = 3 cm) renal masses: correlation of spiral CT features and pathologic findings.
abstract: OBJECTIVE
  We describe our 3-year experience using spiral CT in the evaluation of small renal masses in order to determine the usefulness of this technique for classifying the lesions and to correlate specific CT features with pathologic findings.
  
  
  METHODS
  We retrospectively analyzed spiral CT scans and results of pathologic examinations of surgically extirpated small (< or = 3 cm) renal masses in 35 patients. The masses included 27 renal cell carcinomas, two transitional cell carcinomas, one leiomyoma, one angiomyolipoma, and four benign cysts. Several imaging features, including attenuation, pattern of contrast enhancement, presence and type of calcification, cyst wall, and septation, were correlated with pathologic findings.
  
  
  RESULTS
  Most renal cell carcinomas had a solid growth pattern (n = 19), had attenuation values on unenhanced scans of 20 H or greater (n = 26), and had attenuation values that increased by at least 10 H with contrast enhancement (n = 26). Only three renal cell carcinomas were mostly cystic on pathologic examination. Heterogeneous enhancement correlated with the presence of acellular regions (p = .02). Of 12 cystic masses, spiral CT showed the absence of a thick or nodular fibrous capsule in seven of nine masses (specificity, 0.78) and the absence of several (or nodular) septations in six of seven masses (specificity, 0.86) but was not as sensitive in detecting these features.
  
  
  CONCLUSIONS
  Spiral CT can show many of the key imaging features of small renal masses used to distinguish between benign and malignant lesions. However, despite the theoretical benefits of volumetric CT, some lesions remain indeterminate and require surgical removal for diagnosis.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115.
authors.forename: S G
authors.initials: SG
authors.lastname: Silverman
authors.forename: B Y
authors.initials: BY
authors.lastname: Lee
authors.forename: S E
authors.initials: SE
authors.lastname: Seltzer
authors.forename: D A
authors.initials: DA
authors.lastname: Bloom
authors.forename: C L
authors.initials: CL
authors.lastname: Corless
authors.forename: D F
authors.initials: DF
authors.lastname: Adams
mesh_terms: D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology; D003973:Diatrizoate; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007472:Iohexol; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003973:Diatrizoate; D007472:Iohexol