title: Identification of 5' regulatory regions of the human carnitine palmitoyltransferase II gene.
abstract: We have identified two partially overlapping genomic clones that contain part of the 5' regulatory region of the human carnitine palmitoyltransferase II gene. The 1.2 kb region upstream the transcription start site, as defined by primer extension experiments, shows promoter activity when inserted upstream of a reporter gene and contains a putative insulin responsive element.
authors.affiliation: Istituto Nazionale Neurologico, Divisione di Biochimica e Genetica, Milano, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Montermini
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: E
authors.initials: E
authors.lastname: Verderio
authors.forename: F
authors.initials: F
authors.lastname: Taroni
authors.forename: S
authors.initials: S
authors.lastname: DiDonato
authors.forename: G
authors.initials: G
authors.lastname: Finocchiaro
mesh_terms: D001483:Base Sequence; D002334:Carnitine O-Palmitoyltransferase / Q000096:biosynthesis / Q000235:genetics*; D015500:Chloramphenicol O-Acetyltransferase / Q000235:genetics; D004252:DNA Mutational Analysis; D017930:Genes, Reporter; D015698:Genomic Library; D006801:Humans; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000032:analysis; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*; D014018:Tissue Distribution; D014158:Transcription, Genetic
chemical_list: D012333:RNA, Messenger; D011993:Recombinant Fusion Proteins; D002334:Carnitine O-Palmitoyltransferase; D015500:Chloramphenicol O-Acetyltransferase