[Modification of the radiosensitivity of cultured "Vero" cells by cumene hydroperoxide].
Cumene-hydroperoxide is a radical reaction promoter. Vero cells monolayers treated with this compound were irradiated with gamma-rays and their radiosensitization was compared with that of irradiated, non-treated control cells. Cumene-hydroperoxide treated cells showed a paradoxal radioresistance. We propose a possible buffer-like effect of cumene-hydroperoxide to explain these results.
Drancourt
N
N
Centre de formation et de Recherche sur les Isotopes, les Rayonnements et leurs Applications à la Médecine, l'Industrie et la Radioécologie (I.R.A.M.I.R.), Faculté de Médecine, Marseille, France.
Waultier
S
S
Paulin
R
R
Feugeas
C
C
D000818:Animals; D001555:Benzene Derivatives / Q000494:pharmacology*; D002478:Cells, Cultured; D066298:In Vitro Techniques; D011836:Radiation Tolerance; D014709:Vero Cells / Q000528:radiation effects*
D001555:Benzene Derivatives; C007164:cumene hydroperoxide
Modification de la radiosensibilité de cellules "Vero" en cultures par l'hydroperoxyde de Cumène.