title: [Sodium hypochlorite in the treatment of suppurative peritonitis].
abstract: The method of indirect electrochemical oxidation was used in treatment of 34 patients with acute purulent peritonitis. Twenty patients treated by the traditional method were taken as a group of comparison. The method consists in the elevation of sensitivity of the polyresistant microflora to antibiotics after the introduction into the abdominal cavity of a warmed to 37 degrees C 0.06--0.08% solution of sodium hypochlorite (100-400 ml), buffered with sodium bicarbonate 0.4 g NaHO3 per 100 ml. A combined application of buffered sodium hypochlorite with antibiotics to patients with local, diffuse and general peritonitis resulted in shorter average terms of treatment correspondingly to (9 +/- 0.9), (13 +/- 1.3), (16 +/- 1.9) days against (17.2 +/- 2.4), (25.0 +/- 3.3), (34.7 +/- 4.1) days after traditional methods of treatment. Only 2 patients died of 13 patients with general peritonitis (15.38%). Thus, modelling the processes of oxidative detoxication and phagocytosis with using a transmitter of acute oxygen--an electrolysis solution of sodium hypochlorite is a practically safe and technically simple method of the active action on the inflammatory process in the abdominal cavity, so it may be widely used in treatment of peritonitis.
authors.forename: E A
authors.initials: EA
authors.lastname: Petrosian
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination; D004563:Electrochemistry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000188:drug therapy* / Q000382:microbiology; D011182:Postoperative Care; D012973:Sodium Hypochlorite / Q000627:therapeutic use*; D012996:Solutions
chemical_list: D000900:Anti-Bacterial Agents; D012996:Solutions; D012973:Sodium Hypochlorite
vernacular_title: Gipokhlorit natriia v lechenii gnoĭnogo peritonita.