Chronic hyperoxic effects on cat carotid body catecholamines and structure.
To account for the loss of O2 chemoreception in the cat carotid body during chronic hyperoxia, we studied the putative neurotransmitter correlates. Also, we studied the structural aspect of the carotid body tissues. We found that catecholamine concentrations increased and that the densecored vesicles in the glomus cells were not depleted, indicating that a lack of transmitters was not the cause for the loss of O2 chemoreception.
Mokashi
A
A
Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia 19104-6085.
Di Guilio
C
C
Morelli
L
L
Lahiri
S
S
D000818:Animals; D002344:Carotid Body / Q000378:metabolism* / Q000473:pathology* / Q000648:ultrastructure; D002395:Catecholamines / Q000378:metabolism*; D002415:Cats; D002908:Chronic Disease; D008928:Mitochondria / Q000648:ultrastructure; D010100:Oxygen / Q000097:blood*; D012016:Reference Values
D002395:Catecholamines; D010100:Oxygen