Placebo response in refractory tardive akathisia.
A double-blind, crossover drug trial with a patient with treatment-resistant tardive akathisia is described. The finding of a placebo response was unexpected, but emphasizes the value of such an approach in refractory cases.
Remington
G
G
Department of Psychiatry, University of Toronto, Ontario.
Fornazzari
L
L
Sethna
R
R
D017109:Akathisia, Drug-Induced / Q000188:drug therapy* / Q000523:psychology; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003975:Diazepam / Q000008:administration & dosage; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D015990:Placebo Effect; D011433:Propranolol / Q000008:administration & dosage; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D013747:Tetrabenazine / Q000008:administration & dosage
D014150:Antipsychotic Agents; D011433:Propranolol; D003975:Diazepam; D013747:Tetrabenazine