title: Isolation of anti-Beijing-1 group-specific monoclonal antibody and antigenic analysis of Japanese encephalitis viruses in India.
abstract: Based on the reactivities of monoclonal antibodies, we previously reported that 25 Japanese encephalitis (JE) virus strains fell into five antigenic groups: Nakayama, Beijing-1, Kamiyama, 691004 and Muar. In the present study, we produced monoclonal antibodies against the Beijing-1 strain and obtained the Beijing-1 group-specific antibody, designated BEGMA 1. Furthermore, antigenic comparison of the seven JE virus strains isolated in India was performed by using BEGMA 1 and other group-specific antibodies. The results showed that six strains fell into the Kamiyama group to which the currently prevalent strains in Japan belong.
authors.affiliation: Department of Internal Medicine, School of Medicine, Ehime University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Satake
authors.forename: H
authors.initials: H
authors.lastname: Hasegawa
authors.forename: M
authors.initials: M
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology / Q000302:isolation & purification; D000914:Antibodies, Viral / Q000276:immunology / Q000302:isolation & purification; D000956:Antigens, Viral / Q000032:analysis*; D004664:Encephalitis Virus, Japanese / Q000276:immunology* / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007194:India; D009500:Neutralization Tests
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D000956:Antigens, Viral