title: Primary clear cell adenocarcinoma of the fallopian tube with brain metastasis: a case report.
abstract: The first reported case of cerebellar metastasis from primary clear cell adenocarcinoma of the fallopian tube is presented. Initially diagnosed as stage Ia, the patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and omentectomy, followed by cisplatin-based chemotherapy and whole pelvic irradiation. Thirty six months later multiple pulmonary metastases were detected that did not respond to chemotherapy. Later the patient presented with cerebellar metastasis. She received whole brain radiotherapy and steroids. The brain lesion partially responded and the patient's neurologic symptoms improved. Throughout there was no evidence of local recurrence. This case suggests that with the prolonged survival achieved by aggressive treatment occult brain metastases might become apparent.
authors.affiliation: Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ryuko
authors.forename: O
authors.initials: O
authors.lastname: Iwanari
authors.forename: A
authors.initials: A
authors.lastname: Abu-Musa
authors.forename: R
authors.initials: R
authors.lastname: Fujiwaki
authors.forename: M
authors.initials: M
authors.lastname: Kitao
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000556:secondary*; D001932:Brain Neoplasms / Q000556:secondary*; D005185:Fallopian Tube Neoplasms / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008875:Middle Aged