title: Multiple eruptive keratoacanthoma and immunity disorders.
abstract: A 68-year-old woman presents multiple keratoacanthoma of the Witten and Zak type associated with immunity disorders. A dramatic regression of the lesions is noticed while the patient is treated with an association of loratadine and ranitidine. Hypotheses are proposed in view of a possible role of ranitidine, an anti-H2 antihistaminic.
authors.affiliation: Clinic of Dermatology, University Hospital Saint-Pierre and Brugmann, University of Brussels, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Dangoisse
authors.forename: K
authors.initials: K
authors.lastname: Meyvisch
authors.forename: M
authors.initials: M
authors.lastname: Ledoux
mesh_terms: D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis; D004359:Drug Therapy, Combination; D005260:Female; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D007154:Immune System Diseases / Q000150:complications*; D007636:Keratoacanthoma / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D017336:Loratadine / Q000627:therapeutic use; D011899:Ranitidine / Q000627:therapeutic use; D012008:Recurrence
chemical_list: D000974:Antibodies, Antinuclear; D006635:Histamine H2 Antagonists; D017336:Loratadine; D011899:Ranitidine