[Electron microscopic studies of fimbriae and lectin phagocytosis of Salmonella typhimurium variety copenhagen (STMVC)].
On Salmonella typhimurium variatio copenhagen (STMVC) strains, isolated from pigeons with acute Salmonellosis, two types of fimbriae can be identified, depending on different growth conditions. In addition to the common 7 nm fimbriae we were able to demonstrate in the electron microscope, thin, curled fimbriae 3 nm in diameter which are characterized by a mannose-resistant hemagglutination. The simultaneous expression of both types of fimbriae on a single bacterial cell can be induced by transferring a microcolony from agar medium (3 nm fimbriae), to the surface of a nutrient broth (7 nm fimbriae) and continuing the incubation. One selected strain expresses only the thin fimbriae on nearly all the bacteria on an agar medium. These thin fimbriae seem to play a role in the lectinophagocytosis in macrophage cultures. The attachment of Salmonellae mediated by these fimbriae as well as the internalization of fimbriated cells by macrophages is shown in the electron microscope and discussed in respect to infection and immunization.
Grund
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Institut für Mikrobiologie und Tierhygiene des Fachbereichs Veterinärmedizin, Freien Universität Berlin, Deutschland.
Seiler
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A
D000818:Animals; D001715:Bird Diseases / Q000382:microbiology*; D010856:Columbidae / Q000382:microbiology*; D010861:Fimbriae, Bacterial / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D010587:Phagocytosis; D012481:Salmonella Infections, Animal / Q000382:microbiology*; D012486:Salmonella typhimurium / Q000276:immunology / Q000648:ultrastructure*
Elektronenmikroskopische Untersuchungen zu Fimbrien und Lektinophagocytose bei Salmonella Typhimurium variatio copenhagen (STMVC).