title: [Lipidemic alterations in a child with acute lymphoblastic leukemia in treatment with L-aspariginase].
abstract: The case of a child treated for Acute Lymphoblastic Leukemia (LLA) with high-dose L-asparaginase, (HD L-ase) presented alteration who of lipidemic values (rise of total cholesterol and triglyceride values) without toxicity is described. This finding has previously been reported in only a few patients. Parameters normalized with dietetic regimen. The authors underline the importance of the control, in patient during HD L-ase treatment of lipidic values too, especially when parents also have similar alterations.
authors.affiliation: Clinica Pediatrica II, Istituto di Discipline Pediatriche, Università degli Studi di Torino.
authors.forename: E
authors.initials: E
authors.lastname: Barisone
authors.forename: F
authors.initials: F
authors.lastname: Savino
authors.forename: M
authors.initials: M
authors.lastname: Saitta
authors.forename: C
authors.initials: C
authors.lastname: Vivenza
authors.forename: S
authors.initials: S
authors.lastname: Oderda
authors.forename: R
authors.initials: R
authors.lastname: Miniero
authors.forename: E
authors.initials: E
authors.lastname: Madon
mesh_terms: D001215:Asparaginase / Q000008:administration & dosage* / Q000627:therapeutic use*; D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications* / Q000201:enzymology; D050356:Lipid Metabolism; D008429:Maternal Welfare; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*
chemical_list: D001215:Asparaginase
vernacular_title: Alterazioni lipidiche in una bambina affetta da leucemia linfoblastica acuta (LLA) in trattamento con L-asparaginasi.