title: Antimicrobial activity of 5,6-dihydrobenzo-[a]-carbazoles.
abstract: A new series of 5,6-dihydrobenzo[a]carbazoles was synthesized, some showing good antibacterial activity. The presence of a dialkylamino ethyl chain on the 2-, 3- or 4-O-substituent seems to be critical for such activity.
authors.affiliation: Departmento de Tecnologia Farmacéutica, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires, Argentina.
authors.forename: H
authors.initials: H
authors.lastname: Pappa
authors.forename: A
authors.initials: A
authors.lastname: Segall
authors.forename: M T
authors.initials: MT
authors.lastname: Pizzorno
authors.forename: M
authors.initials: M
authors.lastname: Radice
authors.forename: A
authors.initials: A
authors.lastname: Amoroso
authors.forename: G O
authors.initials: GO
authors.lastname: Gutkind
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D002227:Carbazoles / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared
chemical_list: D000890:Anti-Infective Agents; D002227:Carbazoles