title: Disseminated bone marrow metastases from primary breast cancer: detection and follow-up by radioimmune bone marrow scintigraphy.
abstract: Bone scintigraphy of a 40-yr-old patient suffering from primary breast cancer suggested the possibility of diffuse metastases. Bone marrow scintigraphy using 99mTc-labeled monoclonal antibodies (BW 250/183) demonstrated diffuse destruction of bone marrow due to metastatic disease and consecutive bone marrow extension. Bone marrow scintigraphy was highly sensitive in detecting progression of disease in this asymptomatic patient.
authors.affiliation: Department of Nuclear Medicine, University of Bonn, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Rieker
authors.forename: F
authors.initials: F
authors.lastname: Grünwald
authors.forename: G
authors.initials: G
authors.lastname: Layer
authors.forename: C M
authors.initials: CM
authors.lastname: Kurbacher
authors.forename: A L
authors.initials: AL
authors.lastname: Hotze
authors.forename: C
authors.initials: C
authors.lastname: Menzel
authors.forename: H J
authors.initials: HJ
authors.lastname: Biersack
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis / Q000000981:diagnostic imaging; D016719:Radioimmunodetection; D013131:Spine / Q000473:pathology