title: Primary osteosarcoma of the skull--a case report and review of the literature.
abstract: Primary osteosarcoma of the skull (POS) in a young man with intracranial involvement is reported. After an initial transient remission by surgical intervention and chemotherapy, he began to deteriorate due to tumor recurrence and intracranial hemorrhage, and died 15 months following the time of diagnosis. The rarity and poor prognosis of POS are emphasized together with the review of the clinical and therapeutic aspects in the previously reported 98 cases in the literature.
authors.affiliation: Department of Neurosurgery, Daiyukai General Hospital, Ichinomiya City, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Shinoda
authors.forename: T
authors.initials: T
authors.lastname: Kimura
authors.forename: T
authors.initials: T
authors.lastname: Funakoshi
authors.forename: H
authors.initials: H
authors.lastname: Iwata
authors.forename: K
authors.initials: K
authors.lastname: Tange
authors.forename: C
authors.initials: C
authors.lastname: Kasai
authors.forename: Y
authors.initials: Y
authors.lastname: Miyata
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local; D012516:Osteosarcoma / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D011183:Postoperative Complications; D012888:Skull Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D014057:Tomography, X-Ray Computed