Correction of Duncan's syndrome by allogeneic bone marrow transplantation.
Duncan's syndrome (X-linked lymphoproliferative disorder) is a fatal immunodeficiency syndrome of unknown aetiology and without cure. We show that allogeneic bone marrow transplantation can correct the lethal immune deficits in a patient with this syndrome. We suggest that the primary abnormality in Duncan's syndrome is in bone-marrow derived cells.
Williams
L L
LL
Department of Hematology/Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.
Rooney
C M
CM
Conley
M E
ME
Brenner
M K
MK
Krance
R A
RA
Heslop
H E
HE
D016026:Bone Marrow Transplantation; D002648:Child; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000601:surgery*; D008297:Male; D014184:Transplantation, Homologous