title: [Anaphylactic reaction with coronary spasm following coronarography].
abstract: The authors report a case of anaphylactic shock following the injection of iodinated contrast medium for coronary angiography and complicated by two spasms affecting segments II and III of the right coronary. Vasospasm was relieved by the injection of linsidomine, revealing an angiographically healthy segment III. Such complications associated with various substances, notably iodinated contrast media, are rare. They should nevertheless always be borne in mind when evaluating anaphylactic type reactions. Vasoactive mediators (histamine, serotonin, arachidonic acid metabolites) released by the allergic reaction appear to play a major role. Treatment based upon pathogenesis can be proposed.
authors.affiliation: Centre Hospitalier E. Rain, Gonesse.
authors.forename: M
authors.initials: M
authors.lastname: Ghannem
authors.forename: T
authors.initials: T
authors.lastname: Marsepoil
authors.forename: S
authors.initials: S
authors.lastname: Godard
authors.forename: P
authors.initials: P
authors.lastname: Ho
authors.forename: J M
authors.initials: JM
authors.lastname: Monthéli
authors.forename: R
authors.initials: R
authors.lastname: Lainée
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced*; D003287:Contrast Media; D017023:Coronary Angiography / Q000009:adverse effects*; D003329:Coronary Vasospasm / Q000139:chemically induced*; D006801:Humans; D017613:Iodine Compounds / Q000009:adverse effects; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D017613:Iodine Compounds
vernacular_title: Réaction anaphylactique avec spasme coronarien. Au décours d'une coronarographie.