Uncommon presentation of typhoid fever: a case report.
A 24-year-old Chinese woman was admitted for cholestatic jaundice following a short history of fever associated with headache and diarrhoea. She had mild hepatomegaly. Initial laboratory investigations were non-contributory. A percutaneous liver biopsy revealed inflammatory changes more in keeping with a systemic infection than a primary hepatitic problem. Repeat blood and stool cultures finally grew salmonella typhi. Jaundice is a rare manifestation of typhoid fever; it occurs in less than one-third of patients with hepatomegaly. Such a presentation may mimic primary hepatic infections. Awareness of this rare occurrence in typhoid fever would help in early diagnosis and therapy.
Yap
I
I
Department of Medicine, National University Hospital, Singapore.
Wee
A
A
D000328:Adult; D002779:Cholestasis / Q000209:etiology; D005260:Female; D006801:Humans; D014435:Typhoid Fever / Q000150:complications / Q000175:diagnosis*