title: [Tracer kinetic modeling in nuclear medicine].
abstract: For the quantitative measurement of the function of the organs, the data analysis with the modeling has been performed. The basic concepts and assumptions of the modeling in nuclear medicine are described. In the data analysis with tracer kinetic modeling, there are three important factors to be considered. They are the pharmacokinetics of the tracer in the tissue, the conditions of the study such as data acquisition method and study protocol, and the mathematical methods. We mention many effects of these factors on the values and the interpretation of the results of the examination. For the clinical practice, more simplex methods of measurements and mathematical analysis are desired.
authors.affiliation: Positron Medical Center, Tokyo Metropolitan Institute of Gerontology.
authors.forename: H
authors.initials: H
authors.lastname: Toyama
authors.forename: Y
authors.initials: Y
authors.lastname: Kimura
mesh_terms: D001345:Autoradiography / Q000379:methods; D006801:Humans; D008433:Mathematics; D008962:Models, Theoretical; D009683:Nuclear Medicine; D011868:Radioisotopes / Q000493:pharmacokinetics*
chemical_list: D011868:Radioisotopes