[Alternanthera philoxeroides (Mavt.) Griseb protection against fetal epidemic hemorrhagic fever virus infection in suckling mice].
It has been confirmed that Alternanthera philoxeroides (APG) can markedly protect suckling mice from being infected by epidemic hemorrhagic fever (EHF) virus. After the infected mice were treated with the effective components their survival rate increased, pathological lesion and virus antigen in the tissues mitigated as compared with the controls. Therapeutical dose of APG caused only slight deformation of the hepatic cells.
Qu
C F
CF
Virus Research Institute, Hubei Medical College, Wuhan.
Yang
Z Q
ZQ
Xiang
J M
JM
D000818:Animals; D000833:Animals, Suckling; D000956:Antigens, Viral / Q000032:analysis; D001921:Brain / Q000276:immunology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use* / Q000633:toxicity; D006476:Orthohantavirus / Q000276:immunology; D006480:Hemorrhagic Fever with Renal Syndrome / Q000188:drug therapy* / Q000276:immunology; D007928:Lethal Dose 50; D008168:Lung / Q000276:immunology; D051379:Mice
D000956:Antigens, Viral; D004365:Drugs, Chinese Herbal