How B and T cells talk to each other.
The B cells of the immune system, which secrete antibodies against foreign antigens, are fully specific and effective only after maturation in lymph nodes and other lymphoid tissues. Immunocompetent T cells play a crucial part in this process, but the molecular details of the way in which the two cell types interact have only recently become apparent.
Clark
E A
EA
Department of Microbiology, University of Washington Medical Center, Seattle 98195.
Ledbetter
J A
JA
D000818:Animals; D015703:Antigens, CD / Q000502:physiology; D001402:B-Lymphocytes / Q000502:physiology*; D015815:Cell Adhesion Molecules / Q000502:physiology; D002450:Cell Communication / Q000502:physiology; D006801:Humans; D008213:Lymphocyte Activation / Q000502:physiology; D011947:Receptors, Antigen, B-Cell / Q000502:physiology; D013601:T-Lymphocytes / Q000502:physiology*
D015703:Antigens, CD; D015815:Cell Adhesion Molecules; D011947:Receptors, Antigen, B-Cell