title: The Epstein-Barr virus-associated protein p105 is not encoded by the Epstein-Barr virus genome.
abstract: Rabbit antibodies made to an Epstein-Barr virus (EBV)-associated hydrophobic protein p105 that cross-reacts antigenically with the herpes simplex virus glycoprotein gB inhibited the ability of EBV to induce immunoglobulin synthesis by normal B cells. Sequencing of p105 indicated that it was a keratin-like protein and not encoded by EBV. Analysis of EBV-producing cells with and without mycoplasma indicated that p105 is probably a mycoplasma protein that associates with the EBV virion.
authors.affiliation: School of Biological Sciences, University of Missouri-Kansas City 64110-2499.
authors.forename: S M
authors.initials: SM
authors.lastname: Turk
authors.forename: L M
authors.initials: LM
authors.lastname: Hutt-Fletcher
mesh_terms: D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal / Q000276:immunology; D016477:Artifacts; D001426:Bacterial Proteins / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D002478:Cells, Cultured / Q000382:microbiology; D003429:Cross Reactions; D016679:Genome, Viral; D004854:Herpesvirus 4, Human / Q000254:growth & development*; D008969:Molecular Sequence Data; D009174:Mycoplasma / Q000235:genetics* / Q000276:immunology; D017421:Sequence Analysis; D014759:Viral Envelope Proteins / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D001426:Bacterial Proteins; C086269:Epstein-Barr virus-associated protein p105, bacteria; D014759:Viral Envelope Proteins; C040495:glycoprotein B, Simplexvirus