Double-chambered right ventricle and Down's syndrome: a proposed new association.
Twenty-two cases of double-chambered right ventricle studied in detail from two different centers comprise the study population. Of these, 5 have trisomy-21 Down's syndrome; these five cases, comprising nearly 25% of the entire study group, were essentially evenly divided between the two centers. This unexpectedly high percentage of Down's syndrome associated with such an unusual cardiovascular malformation, albeit among a small population, is likened to the currently recognized and similar association of Down's syndrome and atrioventricular cushion deformities.
Eltohami
E A
EA
Department of Cardiology and Cardiovascular Surgery, Hamad General Hospital, Doha, Qatar.
Hajar
H A
HA
Folger
G M
GM
D002675:Child, Preschool; D017023:Coronary Angiography; D004314:Down Syndrome / Q000150:complications*; D004562:Electrocardiography; D005260:Female; D006326:Heart Auscultation; D006330:Heart Defects, Congenital / Q000150:complications* / Q000175:diagnosis; D006352:Heart Ventricles / Q000002:abnormalities; D006801:Humans; D007223:Infant; D008297:Male