[The effect of x-ray and NMR contrast agents on lipid peroxidation in the normal and pathological kidneys of rats].
It has been studied in vivo and vitro effects of and NMR contrast media on renal lipid peroxidation in intact rats and animals with experimental pathologies; glycerine nephritis and CCL4 intoxication. The effects of contrast media was dependent on the time of application, their concentration and conditions of elimination organs. The value of contrast media effect was decreased in order: GdCl3, bilignost, triombrast, iogexol, omnipaque. Gd-DTPA did not influence lipid peroxidation in any cases.
Bolotova
E N
EN
Sergeev
P V
PV
Shimanovskiĭ
N L
NL
Kerimaliev
M K
MK
D058186:Acute Kidney Injury / Q000139:chemically induced / Q000378:metabolism; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000150:complications / Q000378:metabolism; D003287:Contrast Media / Q000494:pharmacology*; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D005990:Glycerol; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D017114:Liver Failure, Acute / Q000139:chemically induced / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051381:Rats; D013997:Time Factors
D003287:Contrast Media; D005990:Glycerol
Vliianie rentgeno- i IaMR-kontrastnykh sredstv na perekisnoe okislenie lipidov v pochkakh krys v norme i patologii.