Micrognathia after radiation therapy for childhood facial tumors. Report of two cases with long-term follow-up.
As the survival duration and cure rate of children with malignant conditions improve, awareness of long-term side effects is crucial. Two case reports demonstrate long-term changes in dentition and orofacial development in children who had been treated for facial malignant conditions. Changes induced mandibular and maxillary hypoplasia, partial anodontia, microdontia, altered eruption pattern, root stunting, and altered amelogenesis.
Kaste
S C
SC
Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tenn.
Hopkins
K P
KP
D002675:Child, Preschool; D016371:Cranial Irradiation / Q000009:adverse effects*; D018222:Desmoid Tumors / Q000532:radiotherapy; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D007568:Jaw / Q000528:radiation effects*; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy; D009805:Odontogenesis / Q000528:radiation effects*; D018233:Rhabdomyosarcoma, Embryonal / Q000532:radiotherapy; D014078:Tooth Eruption / Q000528:radiation effects*; D014092:Tooth Root / Q000528:radiation effects