Cloning and sequence analysis of the matrix (M) protein gene of rinderpest virus and evidence for another bovine morbillivirus.
We have cloned and sequenced the entire M gene of the vaccine strain of rinderpest virus and that of the virulent Kabete "O" strain from which it was derived. The sequences of these two genes are essentially identical (99% at the nucleotide level), but were very different from a previously published Kabete O M gene sequence (M. Limo and T. Yilma, 1990, Virology 175, 323-327). Inspection of the nucleotide and deduced amino acid sequences of known morbillivirus M genes showed that the earlier sequence was clearly from a morbillivirus, but neither from rinderpest virus nor from peste des petits ruminants virus.
Baron
M D
MD
AFRC Institute for Animal Health, Pirbright Laboratory, Woking, Surrey, UK.
Goatley
L
L
Barrett
T
T
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D003001:Cloning, Molecular; D005814:Genes, Viral / Q000235:genetics*; D008969:Molecular Sequence Data; D018103:Morbillivirus / Q000145:classification / Q000235:genetics*; D012302:Rinderpest virus / Q000145:classification / Q000235:genetics*; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity; D014763:Viral Matrix Proteins / Q000235:genetics*; D014765:Viral Vaccines / Q000235:genetics
D014763:Viral Matrix Proteins; D014765:Viral Vaccines