title: [A case of pneumonitis due to Rikkunshi-to].
abstract: We report a case of pneumonitis due to Rikkunshi-to. A 79-year-old woman was admitted to our hospital because of interstitial pneumonia. She complained of dry cough and dyspnea on exertion. Fine crepitations were heard on physical examination. The chest X-ray film revealed diffuse reticulonodular shadows in both lung fields. Under the suspicion of drug-induced pneumonitis, all drugs were stopped and she was given prednisolone. Consequently her complaints, laboratory data and chest X-ray findings markedly improved. Microscopic examination of transbronchial lung biopsy specimens showed interstitial pneumonia. The results of lymphocyte stimulation test and lymphocyte migration inhibition test were positive for Rikkunshi-to. Based on these findings, we diagnosed this case as pneumonitis due to Rikkunshi-to. To our knowledge, there has been no previous case of pulmonary hypersensitivity due to Rikkunshi-to reported in the world.
authors.affiliation: Department of Internal Medicine, Niigata City General Hospital, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Maruyama
authors.forename: M
authors.initials: M
authors.lastname: Maruyama
authors.forename: T
authors.initials: T
authors.lastname: Takada
authors.forename: M
authors.initials: M
authors.lastname: Haraguchi
authors.forename: K
authors.initials: K
authors.lastname: Uno
mesh_terms: D000368:Aged; D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D005260:Female; D006801:Humans
chemical_list: D004365:Drugs, Chinese Herbal; C084136:liu-jun-zi-tang