[Clinical studies of S-1108, a new oral cephem, in pediatric patients].
Clinical studies of S-1108, a new oral cephem, in pediatric patients were conducted and results are summarized below. 1) Clinical effects of S-1108 against 18 cases of bacterial infections were excellent in 5 cases, good in 10 cases, fair in 1 case and poor in 2 cases, thus the clinical efficacy rates was 83.3%. 2) Bacteriological effects were evaluated in 16 strains. The elimination rate was 100%. 3) No adverse effects nor abnormal laboratory test results were observed in any of the cases.
Yokoo
T
T
Department of Pediatrics, School of Medicine, Nagasaki University.
Hayashi
K
K
Tsuji
Y
Y
Tomimasu
K
K
Kido
T
T
Uehara
Y
Y
Mori
J
J
Mori
G
G
Uchida
T
T
Ootsuka
Y
Y
D000284:Administration, Oral; D000293:Adolescent; D002511:Cephalosporins / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011355:Prodrugs / Q000008:administration & dosage*; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D002511:Cephalosporins; D011355:Prodrugs; C076133:S 1108