Outcome of HIV infected patients on continuous ambulatory peritoneal dialysis.
A retrospective analysis of 39 HIV infected patients with ESRD cared for in New Haven from 1987 to June 1992 was performed. All patients had evidence for HIV infection at the start of CAPD therapy. Cumulative technique survival at one and two years was 43% and 27%, respectively. Only eight patients transferred to center dialysis. One and two year patient survival on CAPD was 58% and 54%, respectively. Mortality was higher in patients with advanced infection than in those with asymptomatic HIV infection. Hospitalization rates were also higher in patients with advanced infection. HIV infected patients had higher rates of peritonitis (3.9 episodes/outpatient CAPD year) compared to non-HIV infected patients (1.5 episodes/CAPD year), especially for pseudomonal and fungal infections. Active injection drug use and use of the "straight set" system were associated with increased rates of peritonitis. CAPD deserves consideration as a therapy for HIV infected patients with ESRD.
Tebben
J A
JA
Department of Medicine, Yale University, New Haven, Connecticut.
Rigsby
M O
MO
Selwyn
P A
PA
Brennan
N
N
Kliger
A
A
Finkelstein
F O
FO
D000328:Adult; D001424:Bacterial Infections / Q000209:etiology; D015496:CD4-Positive T-Lymphocytes; D002408:Catheters, Indwelling / Q000009:adverse effects; D003237:Connecticut / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000150:complications* / Q000401:mortality; D006760:Hospitalization; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000401:mortality / Q000628:therapy*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects; D010538:Peritonitis / Q000209:etiology; D012189:Retrospective Studies; D015996:Survival Rate