Accuracy of ventrolateral thalamic nucleus localization using unreformatted CT scans and the B-R-W system. Experimental studies and clinical findings during functional neurosurgery.
The accuracy with which the ventrolateral thalamic nucleus could be targetted using the BRW stereotactic system and unreformatted axial CT imaging was evaluated in cadaver brains mounted in a skull. Ball bearings (1.82 mm diameter) were placed in the nuclei ventro intermedius (Vim), ventro oralis anterior (Voa) and posterior (Vop) and the brains then sectioned, the locations of the ball bearings relative to the anterior (AC) and posterior commissures (PC) measured and evaluated with reference to a Schaltenbrandt and Bailey stereotactic atlas. Targetting of the ventrolateral thalamic region was frequently accurate (77%) but because of errors in estimation of the AC-PC plane (mean forward angulation of 9 degrees) some ball bearings were placed too deeply in the Fields of and Forel, zona incerta and rostral subthalamic nucleus. Ventrolateral thalamotomy using the BRW stereotactic system and unreformatted axial CT imaging was undertaken in six patients with tremor due to a range of pathologies. The tremor was abolished or altered in four patients whilst no lesion was made in the other two patients since no site that reduced the tremor, could be located. The surgical and clinical implications of this study are discussed.
Whittle
I R
IR
Department of Clinical Neurosciences, Western General Hospital, Edinburgh, Scotland, U.K.
O'Sullivan
M G
MG
Ironside
J W
JW
Sellar
R
R
D004027:Diencephalon / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D013238:Stereotaxic Techniques; D013787:Thalamic Nuclei / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014202:Tremor / Q000000981:diagnostic imaging / Q000601:surgery*