title: A human DEAD box protein with partial homology to heterogeneous nuclear ribonucleoprotein U.
abstract: In a previous report, we showed that a novel DEAD box protein-encoding gene, DDX1, was amplified in two retinoblastoma (RB) cell lines. In addition to the eight conserved motifs that characterize all DEAD box proteins, the deduced amino acid sequence of DDX1 contains a subregion with considerable homology to heterogeneous nuclear ribonucleoprotein U.
authors.affiliation: Department of Oncology, University of Alberta, Edmonton, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Godbout
authors.forename: M
authors.initials: M
authors.lastname: Hale
authors.forename: D
authors.initials: D
authors.lastname: Bisgrove
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D017124:Conserved Sequence; D053487:DEAD-box RNA Helicases; D005134:Eye Neoplasms; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D010447:Peptide Hydrolases / Q000235:genetics*; D020365:RNA Helicases; D012316:RNA Nucleotidyltransferases / Q000235:genetics*; D012175:Retinoblastoma; D012261:Ribonucleoproteins / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D014407:Tumor Cells, Cultured
chemical_list: D034441:Heterogeneous-Nuclear Ribonucleoproteins; D012261:Ribonucleoproteins; D012316:RNA Nucleotidyltransferases; D010447:Peptide Hydrolases; C086252:DDX1 protein, human; D053487:DEAD-box RNA Helicases; D020365:RNA Helicases