title: [Intestinal occlusion in cocaine-packet ingestion].
abstract: During the last decade, the increase of drug traffic and close customs' control have led smugglers to attempt various methods to pass through customs undetected. One method is the ingestion of large numbers of drug-filled packets (usually containing cocaine), together with anticholinergics inhibiting intestinal peristalsis, by a smuggler, called "body-packer" or "mule". The up-to-date approach to cocaine-packet ingestion is conservative medical management during the spontaneous evacuation of the "ovules". Emergency surgical treatment should be reserved for the complications of cocaine-packet ingestion ("body packer syndrome"), which are bowel obstruction due to clustering of the containers and intraluminal rupture of the "ovules" with massive drug transmucous absorption (acute cocaine intoxication). We describe a case of cocaine-packet ingestion in a 19 year old man who was asymptomatic at admission and thus conservatively treated. During the spontaneous evacuation of ovules, clinical and radiological signs of bowel obstruction appeared and the patient underwent emergency laparotomy with removal of 21 containers, two of them clustered in the distal ileum, causing the occlusion. This case gave reasons for a discussion on the specific features of bowel obstruction in cocaine packet ingestion. The bowel obstruction of cocaine-packet ingestion should be carefully considered and promptly treated because of the potentially lethal consequences (death rate of 56% of cases) of transmucous absorption of cocaine contained in "ovules". In fact, while opioid intoxication can be fought with specific antagonists towards opioid receptors (naloxone), the lack of a specific antidote makes cocaine poisoning particularly dangerous.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Clinica Chirurgica Generale, IRCCS Ospedale San Raffaele, Università degli Studi di Milano.
authors.forename: L
authors.initials: L
authors.lastname: Aldrighetti
authors.forename: C
authors.initials: C
authors.lastname: Graci
authors.forename: M
authors.initials: M
authors.lastname: Paganelli
authors.forename: M
authors.initials: M
authors.lastname: Vercesi
authors.forename: M
authors.initials: M
authors.lastname: Catena
authors.forename: G
authors.initials: G
authors.lastname: Ferla
mesh_terms: D000328:Adult; D003042:Cocaine; D003415:Crime; D005547:Foreign Bodies; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D008297:Male
chemical_list: D003042:Cocaine
vernacular_title: L'occlusione intestinale nella cocaine-packet ingestion.