title: Expectant management of premature rupture of membranes with amniotic fluid cultures positive for Ureaplasma urealyticum alone.
abstract: OBJECTIVE
  Our purpose was to determine maternal and neonatal outcome in patients with premature rupture of membranes and amniotic fluid cultures positive for Ureaplasma urealyticum alone.
  
  
  METHODS
  Amniocentesis was performed on 225 patients with premature rupture of membranes at < or = 34 completed weeks of gestation. Amniotic fluid was cultured for aerobic and anaerobic bacteria, Mycoplasma hominis, and Ureaplasma urealyticum. Patients with cultures positive for Ureaplasma urealyticum alone were managed expectantly, including erythromycin and daily biophysical profile examinations.
  
  
  RESULTS
  Thirty-three patients (15%) had amniotic fluid cultures positive for Ureaplasma urealyticum alone, and clinical chorioamnionitis developed in three of these patients. There were no suspected or documented cases of neonatal sepsis. The incidence of infectious morbidity in patients with amniotic fluid cultures positive for Ureaplasma urealyticum alone was not significantly different from that seen in patients with negative cultures.
  
  
  CONCLUSIONS
  An amniotic fluid culture positive for Ureaplasma urealyticum alone may not be an indication for a preterm delivery in patients with premature rupture of membranes.
authors.affiliation: Department of Obstetrics and Gynecology, University of Illinois College of Medicine, Chicago 60612-7313.
authors.forename: D W
authors.initials: DW
authors.lastname: Gauthier
authors.forename: W J
authors.initials: WJ
authors.lastname: Meyer
authors.forename: A
authors.initials: A
authors.lastname: Bieniarz
mesh_terms: D000653:Amniotic Fluid / Q000382:microbiology*; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D007752:Obstetric Labor, Premature / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology / Q000628:therapy*; D011295:Prenatal Care / Q000379:methods; D016869:Ureaplasma Infections / Q000382:microbiology / Q000628:therapy*; D016990:Ureaplasma urealyticum / Q000302:isolation & purification*
chemical_list: D004917:Erythromycin