title: Treatment and control of the intestinal fluke, Skrjabinotrema ovis.
abstract: The small intestinal fluke, Skrjabinotrema ovis, is common among sheep in the Xinjiang region of western China. Up to 65,000 flukes per sheep were found during September when sheep were grazing summer pastures at high altitudes. Efficacy studies of some common flukicides revealed that oxyclosanide and triclabendazole were not effective in reducing the egg output of S. ovis, whereas closantel and praziquantel reduced egg counts by up to 98%. Praziquantel at 25 and 50 mg kg-1 reduced worm counts by 99%. Albendazole at 15 mg kg-1 reduced egg counts by 83% and worm counts by 91% but at lower dose rates it was ineffective.
authors.affiliation: CSIRO, Division of Animal Health, Animal Health Research Laboratory, Parkville, Vic., Australia.
authors.forename: N
authors.initials: N
authors.lastname: Anderson
authors.forename: D A
authors.initials: DA
authors.lastname: Petch
authors.forename: L X
authors.initials: LX
authors.lastname: Tan
authors.forename: X H
authors.initials: XH
authors.lastname: Gong
authors.forename: C
authors.initials: C
authors.lastname: Su
authors.forename: Z M
authors.initials: ZM
authors.lastname: Guo
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use; D002681:China / Q000453:epidemiology; D005243:Feces / Q000469:parasitology; D005260:Female; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D011223:Praziquantel / Q000627:therapeutic use; D015995:Prevalence; D012621:Seasons; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D014201:Trematode Infections / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D000077682:Triclabendazole
chemical_list: D000980:Antiplatyhelmintic Agents; D001562:Benzimidazoles; D000077682:Triclabendazole; D011223:Praziquantel; D015766:Albendazole