Cloning of a cDNA encoding ovine interleukin-3.
A cDNA encoding the ovine hematopoietic growth factor interleukin-3 (IL-3), has been cloned. A 560-bp cDNA, containing the entire protein coding region, was amplified from activated mesenteric lymph node cells. The cDNA was found to share 58% nucleotide identity with hIL-3 and 48% identity with mIL-3. The predicted ovine amino-acid sequence shares 36 and 30% identity, respectively, with the corresponding human and murine proteins.
McInnes
C J
CJ
Moredun Research Institute, Edinburgh, UK.
Logan
M
M
Haig
D
D
Wright
F
F
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary / Q000737:chemistry / Q000235:genetics*; D004274:DNA, Recombinant / Q000737:chemistry / Q000235:genetics; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000235:genetics; D007377:Interleukin-3 / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary; D012756:Sheep
D018076:DNA, Complementary; D004274:DNA, Recombinant; D007377:Interleukin-3; D016178:Granulocyte-Macrophage Colony-Stimulating Factor