[Bone metabolism and Chinese medicinal treatment of menopausal osteoporosis].
48 perimenopausal women were divided into premenopausal (PrM) and postmenopausal (PoM) groups, which were sub-divided into Chinese medicinal herbs (CM) and DES treatment groups, and 12 middle aged women were served as control. E0, E2, T, GH, Ca, P and ALP in the serum and the ratio of Ca/Cr in fasting urine as well as the BMD of right radius was measured. Results showed: The E0, E2 of the PoM were significantly lower than those of the PrM and control groups (P < 0.05, P < 0.01), with no remarkable difference in GH; the T value of PoM was lower than that of control (P < 0.01). Serum Ca and ALP and the ratio of Ca/Cr in fasting urine of the PoM were much higher than those of the control (P < 0.01); the serum Ca and urinary Ca/Cr of the PrM were higher than those of the control (P < 0.05, P < 0.01 respectively). The BMD value of the radius of both PoM and PrM groups were much lower than that of control (P < 0.01), the BMD of the PoM was lower than that of PrM (P < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
Huang
Y H
YH
Dept. of Gyn. & Obs., Xi-Jing Hospital, 4th Military Med. Univ., Xi'an.
Ye
X Q
XQ
D000469:Alkaline Phosphatase / Q000097:blood; D015519:Bone Density; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism; D004054:Diethylstilbestrol / Q000627:therapeutic use*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy* / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D004054:Diethylstilbestrol; D000469:Alkaline Phosphatase; D002118:Calcium