title: Transfer lung factor for Co (TLCO) and its components (DM & VC) in flour mill workers.
abstract: Tlco, Kco (Tlco/Va), Va, Vc and Dm were measured in 25 flour mill workers (non-smoker 9, smoker 16) and 50 healthy control subjects (25 non-smoker, 25 smoker) of similar anthropometric parameters and socio-economic status. Tlco (P < 0.05) was decreased significantly and rest of the parameters were decreased insignificantly in flour mill workers as compared to control subjects. In non-smoker flour mill workers none of the parameters altered significantly as compared to non-smoker control subjects. Statistically significant reduction was seen in smoker workers only in Tlco (P < 0.05) and its component Dm (P < 0.05) as compared to smoker control subjects. Further it has been observed that less duration of flour dust exposure (< 5 years) in all flour mill workers and smoker flour mill workers caused negligible fall in Tlco, whereas longer duration of flour dust exposure (> 5 years) in both the groups caused highly significant fall in Tlco (P < 0.01) which was contributed to by highly significant fall in Dm (P < 0.001).
authors.affiliation: Department of Physiology, Medical College, Rohtak.
authors.forename: R
authors.initials: R
authors.lastname: Kapoor
authors.forename: K K
authors.initials: KK
authors.lastname: Mahajan
authors.forename: R K
authors.initials: RK
authors.lastname: Marya
mesh_terms: D002248:Carbon Monoxide / Q000378:metabolism*; D004391:Dust / Q000009:adverse effects*; D005260:Female; D005433:Flour; D005525:Food-Processing Industry; D006801:Humans; D008297:Male; D016273:Occupational Exposure; D011653:Pulmonary Diffusing Capacity; D012123:Pulmonary Ventilation; D012129:Respiratory Function Tests; D012907:Smoking
chemical_list: D004391:Dust; D002248:Carbon Monoxide