title: Resting metabolic rate is lower in women than in men.
abstract: This study examined gender differences in resting metabolic rate (RMR) across a broad age spectrum after controlling for differences in body composition and aerobic fitness. Three hundred twenty-eight healthy men (17-80 yr) and 194 women (18-81 yr) volunteers were characterized for RMR, body composition, physical activity, peak oxygen consumption (peak VO2), anthropometrics, and energy intake. Measured RMR was 23% higher (P < 0.01) in men (1,740 +/- 194 kcal/day) than in women (1,348 +/- 125 kcal/day). Multiple regression analysis showed that 84% of individual variation in RMR was explained by fat-free mass, fat mass, peak VO2, and gender. After controlling for differences in fat-free mass, fat mass, and peak VO2, a lower RMR (3%; P < 0.01) persisted in women (1,563 +/- 153 kcal/day) compared with men (1,613 +/- 127 kcal/day). Adjusted RMR in premenopausal (P < 0.01) and postmenopausal (P < 0.05) women was lower than in men of a similar age. Our results support a lower RMR in women than in men that is independent of differences in body composition and aerobic fitness.
authors.affiliation: Baltimore Veterans Affairs Medical Center, Division of Gerontology and Geriatric Research Education and Clinical Center, University of Maryland 21201.
authors.forename: P J
authors.initials: PJ
authors.lastname: Arciero
authors.forename: M I
authors.initials: MI
authors.lastname: Goran
authors.forename: E T
authors.initials: ET
authors.lastname: Poehlman
mesh_terms: D000273:Adipose Tissue / Q000502:physiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism; D001823:Body Composition / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008593:Menopause / Q000502:physiology; D008660:Metabolism / Q000502:physiology*; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D010809:Physical Fitness / Q000502:physiology; D017698:Postmenopause / Q000502:physiology; D012727:Sex Characteristics