title: Elastic modulus of prepared canine jejunum, a new vascular graft material.
abstract: The submucosal connective tissue of the jejunum has been shown to be suitable for use as a vascular graft in preliminary dog studies. To partially characterize the mechanical properties of this new graft material, longitudinal stress (sigma)-strain (epsilon)-data were obtained on 13 specimens of canine jejunum, stripped of its mucosal and external smooth-muscle layers. The ratio of stress to strain is the modulus of elasticity (E). It was found that the stress sigma-strain epsilon-data fitted the expression sigma = K epsilon alpha very well. For a typical specimen sigma = 2.69 x 10(6) epsilon 2.33. The modulus of elasticity (E = sigma 1-1/alpha K1/alpha) was found to increase with increasing stress, ranging from about 2,000 to 9,000 mmHg. For the average specimen E = 573 sigma 0.57, where sigma is in mmHg, (1 mmHg = 133.3 Pascals).
authors.affiliation: William A. Hillenbrand Biomedical Engineering Center, Purdue University, West Lafayette, IN 47907.
authors.forename: S T
authors.initials: ST
authors.lastname: Herbert
authors.forename: S F
authors.initials: SF
authors.lastname: Badylak
authors.forename: L A
authors.initials: LA
authors.lastname: Geddes
authors.forename: B
authors.initials: B
authors.lastname: Hillberry
authors.forename: G C
authors.initials: GC
authors.lastname: Lantz
authors.forename: K
authors.initials: K
authors.lastname: Kokini
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001705:Bioprosthesis; D001807:Blood Vessel Prosthesis; D003238:Connective Tissue / Q000637:transplantation*; D004285:Dogs; D004548:Elasticity; D007583:Jejunum / Q000637:transplantation*; D013314:Stress, Mechanical; D013718:Tensile Strength; D014654:Vascular Patency