[Disturbance of the relationship of transmission in male mice carrying the translocation Rb(8,17)1 Iem in combination with t-haplotypes].
t-complex typical feature of the house mouse 17th chromosome is the high transmission (up to 90-95%) of t-carrying chromosome to heterozygous +/t male offspring. The influence of Robertsonian translocation Rb1 (8, 17) Iem at t-haplotype transmission TRD level of heterozygotes Rb1+/+t6, Rb1+/+t12, Rb1+/+tw5, Rb1+/+tw18 in crossing with females of different genotypes was studied. Reliable decrease of TRD level in double heterozygotes of Rb1 and haplotypes t12, tw5, tw18 in comparison with the males ++/+t was discovered. For haplotype t6 no differences in TRD between Rb1+/+t6 and ++/+t6 were recorded. The cause of the obtained results is discussed.
Safronova
L D
LD
Shustrova
I V
IV
Mitrofanov
V G
VG
D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D005298:Fertility / Q000235:genetics; D006239:Haplotypes; D006579:Heterozygote; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D015203:Reproducibility of Results; D014178:Translocation, Genetic
Narushenie sootnosheniia peredachi u samtsov mysheĭ nesushchikh translokatsiiu Rb(8,17)1 Iem v sochetanii s t-gaplotipami.