Successful intestinal transplantation for microvillus inclusion disease.
Microvillus inclusion disease is a rare congenital disorder that presents with severe diarrhea in the newborn period. Multiple therapeutic attempts to control the diarrhea have failed, leading to a chronic dependence on parenteral nutrition and a high infant mortality. This report presents the first child with microvillus inclusion disease in whom small bowel transplantation has been successful, allowing for the administration of total caloric requirements via the enteral route.
Oliva
M M
MM
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Perman
J A
JA
Saavedra
J M
JM
Young-Ramsaran
J
J
Schwarz
K B
KB
D003586:Cytomegalovirus Infections / Q000503:physiopathology / Q000601:surgery*; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007421:Intestine, Small / Q000382:microbiology* / Q000473:pathology / Q000637:transplantation*; D008854:Microscopy, Electron; D008871:Microvilli / Q000382:microbiology; D011182:Postoperative Care