Gastric metaplasia and Helicobacter pylori infection in intestinal tuberculosis.
BACKGROUND
Gastric metaplasia occurs in intestinal epithelium of patients with Helicobacter pylori infection as well as intestinal tuberculosis, but the relationship between the three is not clear.


METHODS
Teaching hospital.


METHODS
Staining of intestinal sections from patients with ileocecal tuberculosis for H pylori and for metaplasia.


RESULTS
Twenty seven of 92 (29.3%) patients demonstrated gastric metaplasia (superficial epithelial and pyloric gland metaplasia) in resected specimens of ileum. Gastric metaplasia was of antral type in all 27 patients. Helicobacter pylori was present in 3 of 27 (11%) patients with gastric metaplasia and was absent in all 65 patients without metaplasia.


CONCLUSIONS
Gastric metaplasia (both superficial epithelial and pyloric gland) occurs in one-third of patients with ileocecal tuberculosis and such mucosa is poorly colonized by H pylori.
Prabhu
S R
SR
Department of Pathology, T N Medical College, Bombay.
Ranganathan
S
S
Parikh
S S
SS
Kalro
R H
RH
D000328:Adult; D005260:Female; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology*; D016481:Helicobacter Infections / Q000150:complications / Q000473:pathology*; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D012189:Retrospective Studies; D014385:Tuberculosis, Gastrointestinal / Q000150:complications / Q000473:pathology*