title: [Lymphocyte subsets and interleukin-2 receptor in breast cancer patients].
abstract: The lymphocyte subsets and IL-2R (p55/Tac) in breast cancer patients were analyzed using monoclonal antibody and flow cytometry until 6 post-operative month. Results were as follows: 1. Lymphocyte fraction of CD3, 4, 8 was maintained from pre-operative to post-operative 6 month. 2. IL-2R value was lower in recurrence group than in breast benign disease group and it was lower. In pre-operative IL-2R in Stage III group than in Stage I and, Stage II. It was lower in DNA aneuploidy group than in DNA diploidy group. 3. At the post-operative 6 month, IL-2R was higher in Stage III group, ly-factor positive group, v-factor positive group and DNA aneuploidy group than in recurrence group. When breast cancer recurred after resection, IL-2R value returned to initial value. In conclusion, IL-2R may be possibly one of the factors of recurrence of breast cancer.
authors.affiliation: Department of Surgery, St. Marianna University School of Medicine, Toyoko Hospital, Kawasaki, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yokose
authors.forename: H
authors.initials: H
authors.lastname: Komoriyama
authors.forename: O
authors.initials: O
authors.lastname: Akaishi
authors.forename: M
authors.initials: M
authors.lastname: Morikubo
authors.forename: T
authors.initials: T
authors.lastname: Yamanaka
authors.forename: S
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: K
authors.initials: K
authors.lastname: Katayama
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000601:surgery; D017252:CD3 Complex / Q000032:analysis; D015496:CD4-Positive T-Lymphocytes; D016827:CD8 Antigens / Q000032:analysis; D005260:Female; D006801:Humans; D016131:Lymphocyte Subsets; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D015375:Receptors, Interleukin-2 / Q000032:analysis*
chemical_list: D017252:CD3 Complex; D016827:CD8 Antigens; D015375:Receptors, Interleukin-2