[The design of a model of the experimental cervical spondylosis].
A model of the cervical spondylosis in the rabbits was established with press-injection of saline into the space between C5 and C6. The formation of the osteophytes at the posterior corner of the vertebra and the slight compression of the spinal cord were found in 4 months after the injection. The swelling, degeneration and rupture of the annulus fibrosus, the regeneration of fibrocartilage cells and the deposition of calcium extending to the posterior part of the vertebral body were observed under light microscope. The pathological changes were similar to those of the cervical spondylosis in the human being.
Zhao
D L
DL
Department of Orthopeadics and Pathology, Changzheng Hospital, Shanghai.
D000818:Animals; D002574:Cervical Vertebrae / Q000473:pathology; D004195:Disease Models, Animal; D011817:Rabbits; D012965:Sodium Chloride; D013128:Spinal Osteophytosis / Q000139:chemically induced / Q000473:pathology
D012965:Sodium Chloride