[Changes in the flow of the stable renal graft following cyclosporin administration].
To evaluate whether oral CyA may produce changes in the renal vascular bed of the graft, a prospective study was made in 16 children with kidney transplant and normal renal function. A exam with echo-Doppler was realized pre and post two hour after CyA was administered. The doses of CyA was 6.1 +/- 2.7 mg/kg/days (3 doses). The results show that CyA produced in the children with kidney transplant an increase of vascular resistance (renal and interlobar) and a decrease transient of urinary flow. The finding changes in relation to time of administration of the CyA.
Bueno
F J
FJ
Unidad de Urología Pediátrica, Hospital Infantil La Paz, Madrid.
Sánchez Peinado
C
C
Alonso
A
A
Prieto
C
C
Meseguer
C G
CG
Navarro
M
M
López Pereira
P
P
Martínez Urrutia
M
M
Jaureguizar
E
E
D000293:Adolescent; D002648:Child; D016572:Cyclosporine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000187:drug effects / Q000502:physiology; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D017595:Renal Plasma Flow / Q000187:drug effects*; D013997:Time Factors; D014463:Ultrasonography; D014563:Urodynamics / Q000187:drug effects
D016572:Cyclosporine
Cambios en el flujo del injerto renal estable tras la administración de ciclosporina.