title: CT-guided and computer assisted stereotactic biopsy. Technique, results, indications.
abstract: On the base of a stereotactic device originally described by Riechert and Mundinger a three-dimensional localization and treatment planning system for CT-guided computer assisted stereotactic procedures has been developed. The experience with 338 patients, in which image guided stereotaxy has been used for the assessment of various intracerebral lesions, is presented. In 54 of these patients the cannula was introduced with a 20 MHz Doppler-probe positioned at the tip of the needle. A comparison of tissue specimens taken stereotactically with tissue material after tumour resection and/or autopsy was performed in 35 patients. The accuracy of the histological diagnosis was 88%. Bleeding as a complication due to the stereotactic intervention occurred in 8 patients (2.4%). Two of these patients had a fatal outcome (mortality: 0.6%). The morbidity (transient and permanent deterioration of the clinical status) was 1.2%.
authors.affiliation: Abteilung für Stereotaxie und funktionelle Neurochirurgie, Neurochirurgische Universitätsklinik, Köln, Federal Republic of Germany.
authors.forename: J
authors.initials: J
authors.lastname: Voges
authors.forename: R
authors.initials: R
authors.lastname: Schröder
authors.forename: H
authors.initials: H
authors.lastname: Treuer
authors.forename: O
authors.initials: O
authors.lastname: Pastyr
authors.forename: W
authors.initials: W
authors.lastname: Schlegel
authors.forename: W J
authors.initials: WJ
authors.lastname: Lorenz
authors.forename: V
authors.initials: V
authors.lastname: Sturm
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000009:adverse effects / Q000295:instrumentation*; D001921:Brain / Q000473:pathology / Q000601:surgery; D001922:Brain Abscess / Q000473:pathology* / Q000601:surgery; D001927:Brain Diseases / Q000473:pathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000473:pathology / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D013238:Stereotaxic Techniques / Q000009:adverse effects / Q000295:instrumentation*; D014057:Tomography, X-Ray Computed / Q000009:adverse effects / Q000295:instrumentation*