title: Peribulbar and retrobulbar anesthesia with prilocaine: a comparison of two methods of local ocular anesthesia.
abstract: Prilocaine (Citanest) has been shown to be a satisfactory alternative to lignocaine, with certain important advantages, including superior diffusion. The latter may be especially important in peribulbar anesthesia, where the level of diffusion is a critical factor in providing a timely, high-quality block. In a prospective randomized study, we compared the effectiveness of peribulbar vs retrobulbar administration of prilocaine. Eighty-seven patients undergoing elective intraocular surgery were randomized to receive either retrobulbar or peribulbar anesthesia with prilocaine 3% with felypressin and hyaluronidase. Pain of injection, akinesia, and anesthesia were evaluated at predetermined intervals after injection. Except for the fact that lid akinesia occurred earlier in the peribulbar group, there was no difference in the quality or rate of onset of overall akinesia in the two groups. Nor were there any differences in the pain associated with injection. Both groups had excellent operative anesthesia and akinesia.
authors.affiliation: Stepping Hill Hospital, Stockport, Manchester SK, United Kingdom.
authors.forename: D C
authors.initials: DC
authors.lastname: Saunders
authors.forename: D A
authors.initials: DA
authors.lastname: Sturgess
authors.forename: C J
authors.initials: CJ
authors.lastname: Pemberton
authors.forename: L H
authors.initials: LH
authors.lastname: Morgan
authors.forename: A
authors.initials: A
authors.lastname: Bourne
mesh_terms: D000368:Aged; D000772:Anesthesia, Local / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009407:Nerve Block; D013508:Ophthalmologic Surgical Procedures; D010146:Pain / Q000209:etiology; D011318:Prilocaine / Q000008:administration & dosage*; D011446:Prospective Studies
chemical_list: D011318:Prilocaine