title: Symptomatic Chiari-I malformation in a patient with acromegaly.
abstract: We describe, for the first time, a patient with both symptomatic acromegaly and Chiari-I malformation. These conditions could coexist by chance alone, but the probability of both presenting simultaneously in a previously healthy man seem quite remote. Alternatively, acromegaly through associated bony and soft tissue enlargement could lead to the development of symptoms from Chiari-I malformation in this patient.
authors.affiliation: Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colo.
authors.forename: H J
authors.initials: HJ
authors.lastname: Lemar
authors.forename: J J
authors.initials: JJ
authors.lastname: Perloff
authors.forename: J A
authors.initials: JA
authors.lastname: Merenich
mesh_terms: D000172:Acromegaly / Q000150:complications* / Q000503:physiopathology*; D000328:Adult; D001921:Brain / Q000002:abnormalities*; D003131:Combined Modality Therapy; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D015282:Octreotide / Q000627:therapeutic use; D010911:Pituitary Neoplasms / Q000503:physiopathology / Q000532:radiotherapy / Q000601:surgery*
chemical_list: D013006:Growth Hormone; D015282:Octreotide