title: Natural genetic engineering of the bacterial genome.
abstract: The term 'natural genetic engineering' means viewing genetic change as a coordinated cell biological process, the reorganization of discrete genomic modules, resulting in the formation of new DNA structures. Examples of natural genetic engineering continue to accumulate, and the concept can be used to integrate observations which demonstrate the similarity between in vitro genetic engineering and the action of in vivo agents of genetic change.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Chicago, Illinois 60637.
authors.forename: J A
authors.initials: JA
authors.lastname: Shapiro
mesh_terms: D004269:DNA, Bacterial / Q000235:genetics / Q000502:physiology; D016680:Genome, Bacterial; D011995:Recombination, Genetic / Q000502:physiology
chemical_list: D004269:DNA, Bacterial