[The dynamic changes in the tissue components of the myocardial layers under compensatory heart hypertrophy in exposure to a peptide hydra morphogen].
Morphometric analysis of the left ventricle myocardial layers under heart hypertrophy was carried out. Values of tissue parameters on the 3rd, 10th and 24th days after 50% coarctation of the abdominal aorta were received. Is shown the heart functioning under conditions of myocardial compensatory hypertrophy development is characterized by expressed zones and different directions of changes of quantitative parameters of tissue components. The single injection of HMP (Hydra morphogen peptide) made the development of myocardial hypertrophy easy at early stages, decreasing depth of manifestations morphologic changes and perhaps affected the time of their development.
Fedoseev
V A
VA
Kazimirskiĭ
A N
AN
Ionina
I A
IA
Lomakina
E B
EB
Rubina
A Iu
AIu
Pylaev
A S
AS
D000222:Adaptation, Physiological / Q000187:drug effects*; D000818:Animals; D006321:Heart / Q000187:drug effects*; D006352:Heart Ventricles / Q000187:drug effects / Q000473:pathology; D017379:Hypertrophy, Left Ventricular / Q000209:etiology / Q000473:pathology*; D008297:Male; D009206:Myocardium / Q000473:pathology*; D009479:Neuropeptides / Q000494:pharmacology*; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D009479:Neuropeptides; C032522:head activator peptide; D011761:Pyrrolidonecarboxylic Acid
Dinamika izmeneniĭ tkanevykh komponentov sloev miokarda v usloviiakh kompensatornoĭ gipertrofii serdtsa pri vozdeĭstvii peptidnogo morfogena gidry.