title: [Morphology of the placenta in genital mycoplasmosis].
abstract: 96 placentas from mothers with genital mycoplasmosis diagnosed during the pregnancy (main group), and without mycoplasmosis (group for comparison) were studied. Histological study was performed in parallel with electron microscopy of the amnion and use of fluorescent antibodies. Progression of the involutive-degenerative changes in the placenta with the development of lipophanerosis and destruction of the extra-placental amnion epithelium were observed in the main group in parallel with the increase of the immunoglobulins studied (A, M, G), fibrinogen, C3-component of the complement with fixation of pathogenic immune complexes (IC). IC are observed in the placenta of 51 +/- 6.35% and in the extra-placental coats in 100% of mothers with mycoplasmosis versus 9 +/- 4.91% and 40%, respectively, in the comparison group. The presence of IC in the placenta and extra-placental coats correlates with the neurological symptoms in newborns and the increase of infectious-allergic diseases in children of the 1st year of life.
authors.forename: E P
authors.initials: EP
authors.lastname: Kalashnikova
authors.forename: A I
authors.initials: AI
authors.lastname: Tanakov
authors.forename: L B
authors.initials: LB
authors.lastname: Zubzhitskaia
authors.forename: V M
authors.initials: VM
authors.lastname: Bobkov
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis; D005260:Female; D005831:Genital Diseases, Female / Q000473:pathology*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D009175:Mycoplasma Infections / Q000473:pathology*; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000473:pathology*
chemical_list: D000936:Antigen-Antibody Complex; D007136:Immunoglobulins
vernacular_title: Morfologiia platsenty pri genital'nom mikoplazmoze.