[Elimination of Toxoplasma gondii through urine of mice in the acute phase of experimental infection].
Toxoplasma gondii tachyzoites from an avirulent strain, were used to subcutaneously infect mice (Swiss outbred strain). All died 7 to 9 days after infection (DAI) during acute phase infection. Eighty per cent eliminated T. gondii forms by urine. This was determined through infectivity test in normal mice (bioprove). Interstitial interbular hemorrhage were the more frequently observed lesion in renal histology. Whole erythrocytes could also be seen in some glomerular Bowmann's subcapsular space. T. gondii elimination mechanism is discussed, together with the relationship between these observations and natural toxoplasmosis transmission.
Rocha
R J
RJ
Dep. de Parasitologia, UNICAMP, Campinas, SP, Brasil.
Tafuri
W L
WL
Chiari
C A
CA
D000818:Animals; D000913:Antibodies, Protozoan / Q000302:isolation & purification; D004195:Disease Models, Animal; D005260:Female; D007668:Kidney / Q000469:parasitology / Q000473:pathology; D051379:Mice; D013997:Time Factors; D014122:Toxoplasma / Q000276:immunology / Q000302:isolation & purification*; D014124:Toxoplasmosis, Animal / Q000635:transmission; D001743:Urinary Bladder / Q000469:parasitology; D014556:Urine / Q000469:parasitology*
D000913:Antibodies, Protozoan
Eliminação de Toxoplasma gondii pela urina de camundongos durante a fase aguda da infecção experimental.