[Effect of immobilization stress on the level of thyroid hormone secretion].
Analysis of blood flowing from the rat thyroid has shown that an acute immobilization stress enhanced thyroid hormone secretion with an increase of the T3/T4 x 100 index. The most marked response to stress was observed after repeated 2 min immobilization with a 3 min interval. Such increase of secretion was arrested by injection of prazosin, an alpha-adrenoblocker. Propylthiouracil injected an hour before the experiment reduced T4 thyroid conversion index. These results permit a conclusion that short-term repeated immobilization enhanced thyroid hormone secretion via alpha-adrenergic system stimulation, this being paralleled by increased production of hormonally more active T3.
Turakulov
Ia Kh
IaKh
Burikhanov
R B
RB
Patkhitdinov
P P
PP
Myslitskaia
A I
AI
D000818:Animals; D008297:Male; D011224:Prazosin / Q000494:pharmacology; D011441:Propylthiouracil / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000503:physiopathology*; D013974:Thyroxine / Q000378:metabolism*; D014284:Triiodothyronine / Q000378:metabolism*
D014284:Triiodothyronine; D011441:Propylthiouracil; D013974:Thyroxine; D011224:Prazosin
Vliianie immobilizatsionnogo stressa na uroven' sekretsii tireoidnykh gormonov.