Influence of adrenalectomy on the developing rat thymus during peri-weaning period.
Adrenalectomy of 17-, 18- and 19-day-old male and female rats did not cause any changes in the weight of thymus 4 days later. Adrenalectomy on day 20 of age induced a significant hypertrophy of the thymus 4 days later. These results indicate that on day 20 of age, just before weaning, the thymus is under some inhibitory regulation by the adrenal gland.
Inomata
T
T
Department of Laboratory Animal Science, Azabu University, School of Veterinary Medicine, Japan.
Hyodo
T
T
Sakita
K
K
Ninomiya
H
H
Showji
Y
Y
Hashimoto
Y
Y
Murakata
S
S
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D005260:Female; D006984:Hypertrophy; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000254:growth & development* / Q000473:pathology; D013997:Time Factors; D014886:Weaning