title: Perinatal transmission of HIV-2 infection in malnourished children in Guinea Bissau.
abstract: Since there have been a few reports of pediatric HIV-2 infection. We therefore investigated the perinatal transmission of HIV-2 in 147 malnourished and 164 well-nourished children attending a health center in the northern part of Guinea Bissau. Specific HIV-2 antibodies were detected in 17 mothers and in 2 malnourished children, one of them with pediatric AIDS. This study demonstrates that mother to child transmission of HIV-2 infection occurs in Guinea Bissau and suggests that there is an increased likelihood of detecting HIV-2 infection in malnourished children. The high seroprevalence of HIV-2 in a rural population without known risk factors may represent a hidden threat to mother/child health.
authors.affiliation: Blood Bank, Hospital Nacional Simao Mendes, Bissau, Republica da Guiné.
authors.forename: A
authors.initials: A
authors.lastname: Ferro
authors.forename: P
authors.initials: P
authors.lastname: Gomez
authors.forename: C
authors.initials: C
authors.lastname: Andrian
authors.forename: A
authors.initials: A
authors.lastname: Perra
authors.forename: O
authors.initials: O
authors.lastname: Frongia
authors.forename: M A
authors.initials: MA
authors.lastname: Sechi
authors.forename: S
authors.initials: S
authors.lastname: Sabbatani
authors.forename: F
authors.initials: F
authors.lastname: Lillo
authors.forename: O E
authors.initials: OE
authors.lastname: Varnier
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000453:epidemiology* / Q000635:transmission*; D015153:Blotting, Western; D015362:Child Nutrition Disorders / Q000150:complications*; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006169:Guinea-Bissau / Q000453:epidemiology; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology* / Q000635:transmission*; D006679:HIV Seropositivity; D015497:HIV-1 / Q000276:immunology; D015498:HIV-2 / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male
chemical_list: D015483:HIV Antibodies