Retinal disease associated with AIDS.
In recent years an enormous amount of new information in the area of retinitis and retinal disease in immunosuppressed patients has been acquired. There have been exciting new developments in our understanding of the pathogenesis of retinal disease in AIDS patients as well as important advances in the diagnosis and therapy of infectious retinitis. This article will summarise the recent advances in this area and outline the direction of future research as it applies to the clinical management of patients with retinal manifestations of AIDS. Diagnostic and therapeutic difficulties will be addressed including the appropriate selection of antiviral drugs and other therapeutic modalities in patients with sight-threatening retinitis.
Freeman
W R
WR
University of California, San Diego, Department of Ophthalmology, Shiley Eye Center, La Jolla 92093-0946.
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy; D017245:Foscarnet / Q000627:therapeutic use; D005654:Fundus Oculi; D015774:Ganciclovir / Q000627:therapeutic use; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D012173:Retinitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology
D017245:Foscarnet; D015774:Ganciclovir