title: Age-adjusted CD4+ lymphocyte parameters in healthy children at risk for infection with the human immunodeficiency virus. The Military Pediatric HIV Consortium.
abstract: Values for CD4+ lymphocytes are reported to vary by age. We evaluated an ethnically diverse population of healthy children at risk for human immunodeficiency virus infection to establish normal ranges for age-adjusted CD4+ lymphocyte parameters. We identified a threshold of approximately 30% CD4+ lymphocytes which corresponded to a 5th percentile for all ages. It is important that no significant differences in absolute CD4+ lymphocyte counts on the basis of ethnic group were found.
authors.affiliation: Department of Pediatrics, Naval Hospital, San Diego, California 92134-5000.
authors.forename: N J
authors.initials: NJ
authors.lastname: Waecker
authors.forename: D P
authors.initials: DP
authors.lastname: Ascher
authors.forename: M L
authors.initials: ML
authors.lastname: Robb
authors.forename: R
authors.initials: R
authors.lastname: Moriarty
authors.forename: M
authors.initials: M
authors.lastname: Krober
authors.forename: W J
authors.initials: WJ
authors.lastname: Rickman
authors.forename: C A
authors.initials: CA
authors.lastname: Butzin
authors.forename: G W
authors.initials: GW
authors.lastname: Fischer
mesh_terms: D000367:Age Factors; D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D015658:HIV Infections / Q000209:etiology; D006801:Humans; D007223:Infant; D007958:Leukocyte Count; D012016:Reference Values; D012307:Risk Factors