[Failure of intravenous immunoglobulins in certain systemic diseases. 5 cases].
Human polyvalent immunoglobulins administered intravenously have shown to be effective in some immune diseases. We administered high dose-IV Ig (2g/kg/session) in five patients with severe chronic systemic diseases. Their condition did not improve, except in one case where a transient response was noticed. Considering the inconsistent results and high cost of IV Ig, double blind studies are required to determine the conditions in which high dose IV Ig may be more effective than conventional treatments.
Bahadoran
P
P
Service de Médecine Interne, Hôpital Avicenne, Bobigny.
De Bandt
M
M
Echard
M
M
Jarrousse
B
B
Guillevin
L
L
D000328:Adult; D003449:Cryoglobulinemia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000188:drug therapy*; D017285:Polymyositis / Q000188:drug therapy*; D012189:Retrospective Studies; D013997:Time Factors
D016756:Immunoglobulins, Intravenous
Echec des immunoglobulines intraveineuses au cours de certaines maladies systémiques. 5 observations.