title: Dopaminergic resistance in a case of invasive macroprolactinoma.
abstract: Invasive prolactinoma is a relatively infrequent variety of macroprolactinoma characterized by a fast and aggressive growth, with infiltration to adjacent structures, and whose management is frequently difficult. We present the case of a fatal invasive macroprolactinoma in whom resistance to different dopaminergic drugs developed.
authors.affiliation: Department of Endocrinology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Schwarzstein
authors.forename: A
authors.initials: A
authors.lastname: García-Patterson
authors.forename: G
authors.initials: G
authors.lastname: Giménez
authors.forename: J
authors.initials: J
authors.lastname: Calaf
authors.forename: M
authors.initials: M
authors.lastname: Puig-Domingo
authors.forename: A
authors.initials: A
authors.lastname: Caixàs
authors.forename: X
authors.initials: X
authors.lastname: Matías-Guiu
authors.forename: S M
authors.initials: SM
authors.lastname: Webb
mesh_terms: D003131:Combined Modality Therapy; D015259:Dopamine Agents / Q000627:therapeutic use*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D015175:Prolactinoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D011859:Radiography
chemical_list: D015259:Dopamine Agents