[Cryptococcal meningitis in pregnancy. Review of the literature. Report of 2 cases].
Two cases of neurocryptococcosis were diagnosed during pregnancy in São Paulo (Brazil). Amphotericin B was used in the second trimester in one patient. The other, received amphotericin B during the first trimester of pregnancy and 5-fluorocytosine was added in the second trimester. In both, the pregnancy was uneventful and the fetus suffered no damage. The therapy used to treat pregnant women with cryptococcal meningitis is commented. The newborn follow-up is discussed. A review of the literature concerning neurocryptococcosis during pregnancy is presented.
Pereira
C A
CA
Disciplina de Doenças Infecciosas e Parasitárias, Escola Paulista de Medicina, São Paulo, Brasil.
Fischman
O
O
Colombo
A L
AL
Moron
A F
AF
Pignatari
A C
AC
D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D005437:Flucytosine / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007275:Injections, Intravenous; D016919:Meningitis, Cryptococcal / Q000188:drug therapy*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*
D000666:Amphotericin B; D005437:Flucytosine
Neurocriptococose durante a gravidez. Revisão da literatura. Relato de dois casos.