Primary biliary cirrhosis. Sole presentation with rampant dental caries.
A 55-year-old woman was referred by her general dental practitioner for management of rampant dental caries of recent onset. Examination revealed a very dry mouth, angular stomatitis, and multiple carious lesions. Labial salivary gland biopsy showed features consistent with Sjögren's syndrome. Hematologic investigations showed antimitochondrial antibodies at a titer of 1 in 320, highly suggestive of primary biliary cirrhosis that was confirmed by liver biopsy.
Richards
A
A
University Department of Oral Medicine, Pathology and Microbiology, Bristol Dental School and Health, UK.
Rooney
J
J
Prime
S
S
Scully
C
C
D001323:Autoantibodies / Q000097:blood; D003731:Dental Caries / Q000209:etiology*; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications*; D008875:Middle Aged; D008930:Mitochondria, Liver / Q000276:immunology; D014987:Xerostomia / Q000209:etiology*
D001323:Autoantibodies