title: Advances in respiratory therapeutics in children.
abstract: A wide range of topics can be covered when considering a review of respiratory therapeutics. This review focuses on advances and controversies in the therapy of asthma, including issues regarding medications such as inhaled beta 2-agonists, inhaled corticosteroids, cromolyn sodium, and theophylline. Bronchodilator therapy for acute viral bronchiolitis remains a controversial issue and is discussed in light of recent published manuscripts. Issues regarding surfactant therapy for respiratory distress syndrome remain prominent in the neonatal respiratory therapeutics literature and recent findings in this area are reported. Advances in the treatment of cystic fibrosis, as well as a review concerning the pulmonary toxicity of various medications used in the treatment of pediatric illness are discussed.
authors.affiliation: Chest Division, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: J J
authors.initials: JJ
authors.lastname: Reisman
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy*; D001990:Bronchiolitis, Viral / Q000188:drug therapy; D001993:Bronchodilator Agents / Q000627:therapeutic use; D019819:Budesonide; D002648:Child; D003550:Cystic Fibrosis / Q000188:drug therapy; D006486:Hemosiderosis / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D008171:Lung Diseases / Q000188:drug therapy*; D008727:Methotrexate / Q000627:therapeutic use; D011282:Pregnenediones / Q000627:therapeutic use; D011663:Pulmonary Surfactants / Q000627:therapeutic use; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy; D013806:Theophylline / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D011282:Pregnenediones; D011663:Pulmonary Surfactants; D019819:Budesonide; D013806:Theophylline; D008727:Methotrexate