[Oral glucose tolerance and HbA1c in the diagnosis of pregnancy in diabetes].
This study was undertaken in order to evaluate the plasma glucose response to oral glucose tolerance test (OGTT, 100 g) and the HbA1c values in pregnant women at different gestational ages. One-hundred twenty-nine OGTTs have been performed in 75 pregnancies. The results obtained show a decrease in glucose tolerance during pregnancy. Mean HbA1c value was significantly higher in women with gestational diabetes mellitus, but values of subjects with gestational diabetes and normal glucose tolerance overlapped widely. In conclusion, HbA1c is not a sensitive parameter in the diagnosis of gestational diabetes mellitus. Further studies are necessary to evaluate its specificity and prognostic significance.
Indraccolo
S R
SR
Scuola Autonoma di Ostetricia di Camerino, Università degli Studi di Roma La Sapienza.
Cartechini
M G
MG
Mazzoli
G W
GW
Fabi
F
F
Negroni
M G
MG
Compagnucci
P
P
D000284:Administration, Oral; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008423:Maternal Age; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood* / Q000175:diagnosis; D011379:Prognosis
D001786:Blood Glucose; D006442:Glycated Hemoglobin
Carico orale di glucosio ed HbA1c nella diagnosi di diabete gestazionle.