Duodenal ulcer in the Sudan. Clinical features and treatment with H2 blockers.
In a prospective study, 168 Sudanese patients with endoscopically proven duodenal ulcer were studied. The mean age was 36 (SD 3) years and the male:female ratio was 3:1. Most of the patients belonged to the lower social class (class 3) and the chief presenting features were long standing epigastric pain (72.6%), heartburn (66.4%) and upper gastrointestinal bleeding (45.5%). The endoscopic appearance of the ulcers was severe in 40% of patients; this, together with the genetic and distinct dietary factors, may have contributed to the low healing rates following treatment with H2 receptor blockers.
Ahmed M el-B
Soba University Hospital, Khartoum, Sudan.
Arbab
B M
BM
Homeida
M M
MM
D000293:Adolescent; D000328:Adult; D002927:Cimetidine / Q000627:therapeutic use*; D004381:Duodenal Ulcer / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D011899:Ranitidine / Q000627:therapeutic use*; D016037:Single-Blind Method; D013397:Sudan; D016896:Treatment Outcome
D002927:Cimetidine; D011899:Ranitidine