[Effects of replenishing kidney herbs on estrogen and 1,25-dihydroxyvitamin D3 of dexamethasone-induced rats model with osteoporosis].
Estrogen and 1,25-(OH)2-D3 change in rats with osteoporosis induced by dexamethasone (DXM) was observed. The calcium and replenishing Kidney Herbs (RKH) was used in treating osteoporosis. The results shown: The level of estrogen and 1,25-(OH)2-D3 in rats with osteoporosis was lower than that of the normal. Calcium and RKH were effective in treating osteoporosis and they could recover the level of estrogen and 1,25-(OH)2-D3 to normal state, the effect of RKH was better than that of calcium. There was positive correlation between the level of estrogen and 1,25-(OH)2-D3. The treatment of RKH might be an optimal method for osteoporotic treatment.
Liu
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HD
Dept. of Biochemistry, Hebei Medical College, Shijiazhuang.
Li
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Tong
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D000818:Animals; D002117:Calcitriol / Q000097:blood*; D002118:Calcium / Q000627:therapeutic use; D003907:Dexamethasone; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004958:Estradiol / Q000097:blood*; D005260:Female; D010024:Osteoporosis / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal; D004958:Estradiol; D003907:Dexamethasone; D002117:Calcitriol; D002118:Calcium