title: The use of muscle flaps for salvage of failed total knee arthroplasty.
abstract: Deep infections occur in 1-5% of all patients undergoing total knee arthroplasty, and may result in failure of the prosthesis and subsequent arthrodesis. Two-stage reimplantation is often successful, but depends upon the presence of good soft tissue coverage. We have treated 9 patients in whom chronic infection developed which required removal of the prosthesis, debridement, and implantation of antibiotic impregnated spacers for control. These patients all had poor quality soft tissue cover precluding prosthesis reimplantation. The use of muscle flaps resulted in 7 of the 9 patients having successful reimplantation of a prosthesis and remaining free of infection in a follow-up ranging from 1-5 years.
authors.affiliation: Department of Plastic Surgery, Cleveland Clinic Foundation, Ohio.
authors.forename: E Z
authors.initials: EZ
authors.lastname: Browne
authors.forename: B N
authors.initials: BN
authors.lastname: Stulberg
authors.forename: R
authors.initials: R
authors.lastname: Sood
mesh_terms: D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000628:therapy*; D005260:Female; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000637:transplantation*; D019736:Prostheses and Implants; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000628:therapy*; D012086:Reoperation; D016879:Salvage Therapy; D013524:Surgical Flaps / Q000379:methods*; D014031:Tobramycin / Q000008:administration & dosage / Q000627:therapeutic use; D014640:Vancomycin / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D014640:Vancomycin; D014031:Tobramycin