Ketorolac as a component of balanced analgesia after thoracotomy.
Ketorolac 10 mg or 30 mg i.m., 6 hourly or placebo was given to 75 patients who had undergone thoracotomy, in a randomized double-blind study. All subjects were given intercostal nerve blocks with bupivacaine and had access to i.v. patient-controlled morphine. I.m. ketorolac improved the success rate of the analgesic regimen, with fewer patients withdrawing from the study because of inadequate pain relief.
Power
I
I
University Department of Anaesthetics, Royal Infirmary of Edinburgh.
Bowler
G M
GM
Pugh
G C
GC
Chambers
W A
WA
D000328:Adult; D000368:Aged; D000698:Analgesia; D002045:Bupivacaine / Q000008:administration & dosage; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D020911:Ketorolac Tromethamine; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000627:therapeutic use; D009407:Nerve Block; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D013908:Thoracotomy; D014046:Tolmetin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014325:Tromethamine / Q000627:therapeutic use*
D004338:Drug Combinations; D014325:Tromethamine; D020911:Ketorolac Tromethamine; D009020:Morphine; D014046:Tolmetin; D002045:Bupivacaine