[Fundamental concepts in the implementation of the spectroscopic magnetic resonance for the determination of the biological quality of human cartilage transplants].
Cartilage grafts are often used in reconstructive surgery for compensating loss or defect in tissues. Future progress in this field are related to the resolution of some problems concerning the preservation in our tissue-banks. Several time-expensive biochemical, histological and autoradiographic methods have been employed in the past to describe the metabolic properties and pathological changes of preserved and transplanted cartilage grafts. In this article we show that magnetic resonance spectroscopy offers the possibility to recognize metabolic changes in cartilage tissues as a consequence of storage conditions: anaerobic metabolism (lactacte) and lysis of collagenic structures of the matrix. In this way objective parameters assessing the biologic quality of grafts can be obtained without any destructive impact on the specimen.
Bujía
J
J
Departamento de Otorrinolaringolgía, Ludwig-Maximilians Universidad de Munich, Germany.
Osete
J M
JM
Sprekelsen
C
C
Reimann
V
V
Hammer
C
C
D002102:Cadaver; D002356:Cartilage / Q000378:metabolism / Q000637:transplantation*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D009132:Muscles / Q000378:metabolism; D009296:Nasal Cavity / Q000378:metabolism; D012272:Ribs / Q000378:metabolism; D014021:Tissue Preservation; D016378:Tissue Transplantation
Conceptos básicos en el empleo de la resonancia magnética espectroscópica para determinar la calidad biológica de trasplantes de cartílago humano.