title: Implicit memory in patients with schizophrenia and normal controls: effects of task demands on susceptibility to priming.
abstract: Two experiments employing a stem-completion priming paradigm are reported. The first of these compared patients with schizophrenia (SC) to normal controls and demonstrated impaired implicit memory in the SC patients under task conditions identical to those used previously with other patient groups. The second experiment was designed to examine the effects of implicit task demands and stimulus selection upon susceptibility to priming, with a second group of SC patients and normal controls. Results indicated that the ability to carry out the task demands of the implicit condition (i.e., generate completions for word-stems) was inversely related to susceptibility to priming in both the SC patients and controls. In addition, the baseline probability of specific completions was found to be correlated with the ease of priming those completions, suggesting a possible mechanism for producing statistical dissociations between implicit and explicit retrieval conditions with this paradigm. These findings suggest that certain implicit tasks may be susceptible to nonmemory psychological influences that have not been adequately investigated to date; these may be responsible for "normalizing" the performance of amnesic patients as well as producing statistical dissociations from explicit memory tasks.
authors.affiliation: Clinical Brain Disorders Branch, IRP, NIMH, Bethesda, MD 20892.
authors.forename: C
authors.initials: C
authors.lastname: Randolph
authors.forename: J M
authors.initials: JM
authors.lastname: Gold
authors.forename: C J
authors.initials: CJ
authors.lastname: Carpenter
authors.forename: T E
authors.initials: TE
authors.lastname: Goldberg
authors.forename: D R
authors.initials: DR
authors.lastname: Weinberger
mesh_terms: D000328:Adult; D000425:Alcohol Amnestic Disorder / Q000523:psychology; D000544:Alzheimer Disease / Q000523:psychology; D003463:Cues; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000523:psychology; D008297:Male; D008568:Memory / Q000502:physiology*; D008569:Memory Disorders / Q000523:psychology; D011939:Mental Recall; D011569:Psychiatric Status Rating Scales; D012565:Schizophrenic Psychology