[Contribution to the study of the mechanism of action of potassium channel activators].
Radioisotopic studies have been performed on insulin secreting cells in order to characterize the mode of action of the "K+ channel openers". The study reveals that these pharmacologic agents interfere with the K(+)-ATP channels.
Lebrun
P
P
Laboratoire de Pharmacologie, Université libre de Bruxelles.
D000959:Antihypertensive Agents / Q000494:pharmacology; D015220:Calcium Channels / Q000187:drug effects; D006146:Guanidines / Q000494:pharmacology*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D020110:Pinacidil; D015221:Potassium Channels / Q000187:drug effects*; D013237:Stereoisomerism
D000959:Antihypertensive Agents; D015220:Calcium Channels; D006146:Guanidines; D007328:Insulin; D015221:Potassium Channels; D020110:Pinacidil
Contribution à l'étude du mode d'action des activateurs des canaux potassiques.