title: Thermal biofeedback as an effective substitute for sympatholytic medication in moderate hypertension: a failure to replicate.
abstract: Thirty-three moderate hypertensives were converted to a 2-drug regimen of metoprolol and diuretic and BPs stabilized at a well-controlled level. They then completed one of three conditions over an 8-week interval: (I) 16 sessions of TBF (hand and foot warming); (II) 16 sessions of frontal EMG-BF; (III) regular home monitoring of BP. Attempts were then made to withdraw the patients from the sympatholytic medication. Those successfully withdrawn were followed up for one year. There were no significant advantages for TBF over the other two conditions in the short term or with long-term follow-up. Only 27% of treated patients (including Condition III failures who were remedicated and treated with TBF) were successfully off of the sympatholytic at a one-year follow-up. The generally poor results on clinical outcome were confirmed by clinic BPs, home BPs by patients, and 24-hour ambulatory BPs.
authors.affiliation: SUNY--Albany.
authors.forename: E B
authors.initials: EB
authors.lastname: Blanchard
authors.forename: G
authors.initials: G
authors.lastname: Eisele
authors.forename: M A
authors.initials: MA
authors.lastname: Gordon
authors.forename: P J
authors.initials: PJ
authors.lastname: Cornish
authors.forename: D A
authors.initials: DA
authors.lastname: Wittrock
authors.forename: L
authors.initials: L
authors.lastname: Gilmore
authors.forename: A J
authors.initials: AJ
authors.lastname: Vollmer
authors.forename: C
authors.initials: C
authors.lastname: Wan
mesh_terms: D001676:Biofeedback, Psychology; D001794:Blood Pressure; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000628:therapy*; D008297:Male; D008790:Metoprolol / Q000627:therapeutic use; D008875:Middle Aged; D015203:Reproducibility of Results
chemical_list: D004232:Diuretics; D008790:Metoprolol