title: Ceftazidime-related nonconvulsive status epilepticus.
abstract: The third-generation cephalosporin, ceftazidime, is widely used for the treatment of serious gram-negative infections. As is true of cephalosporins in general, reported adverse effects have been few. We report a case of ceftazidime-induced status epilepticus in a patient with Pseudomonas aeruginosa meningitis and compare the clinical manifestations of this case with those of two previously described cases of ceftazidime-related encephalopathy. This diagnosis should be entertained and an electroencephalogram should be obtained in all patients with myoclonus and/or altered mental status while they are receiving ceftazidime therapy.
authors.affiliation: Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City.
authors.forename: A D
authors.initials: AD
authors.lastname: Klion
authors.forename: J
authors.initials: J
authors.lastname: Kallsen
authors.forename: C T
authors.initials: CT
authors.lastname: Cowl
authors.forename: W M
authors.initials: WM
authors.lastname: Nauseef
mesh_terms: D000368:Aged; D002442:Ceftazidime / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy; D011552:Pseudomonas Infections / Q000188:drug therapy; D013226:Status Epilepticus / Q000139:chemically induced*
chemical_list: D002442:Ceftazidime