A long-range restriction map of human chromosome 5q21-q23.
A long-range restriction map encompassing the APC (adenomatous polyposis coli) gene has been constructed. The map includes 35 DNA markers and consists of two segments of 10 and 2.5 Mb. Published genetic markers have been connected using additional, nonpolymorphic DNA probes. The map clarifies marker order and allows comparison of physical and genetic data.
Ward
J R
JR
Molecular Analysis of Mammalian Mutation Laboratory, Imperial Cancer Research Fund, Lincoln's Inn Fields, London, United Kingdom.
Cottrell
S
S
Thomas
H J
HJ
Jones
T A
TA
Howe
C M
CM
Hampton
G M
GM
Deaven
L
L
Sheer
D
D
Bodmer
W F
WF
Solomon
E
E
D011125:Adenomatous Polyposis Coli / Q000235:genetics*; D015825:Chromosomes, Fungal; D002895:Chromosomes, Human, Pair 5; D003360:Cosmids; D015342:DNA Probes; D015723:Gene Library; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D012150:Polymorphism, Restriction Fragment Length; D015183:Restriction Mapping
D015342:DNA Probes; D005819:Genetic Markers