title: [Tuberculosis prevention needs adaptation to conditions of Central European countries].
abstract: Recommendations to stop mandatory BCG vaccination were issued for countries with a favourable epidemiological situation by tuberculosis. In three regions of Czechia nonvaccinated children made up 160,000. By tuberculin test, annual risk to develop tuberculous infection in children aged 0-6 years amounted to 0.05% (31 children). The transition of the infection into the disease for 6-year follow-up reached 15-20%. The analysis of the cost-effect values for BCG vaccination of the newborns from 1986 revealed that the disease was prevented in 1 out of 6 potential cases per 100,000 vaccinated children, there were also adverse effects of the vaccination. The cost of the vaccination would be much higher than the cost of prevented deaths of tuberculosis. Thus, it is thought valid to do vaccination to children at more advanced age.
authors.forename: L
authors.initials: L
authors.lastname: Trnka
authors.forename: D
authors.initials: D
authors.lastname: Dankova
mesh_terms: D001500:BCG Vaccine; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D018153:Czech Republic / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012307:Risk Factors; D014376:Tuberculosis / Q000453:epidemiology / Q000517:prevention & control*; D014611:Vaccination / Q000009:adverse effects / Q000191:economics
chemical_list: D001500:BCG Vaccine
vernacular_title: Kontrol za tuberkulëzom nuzhdaetsia v adaptatsii k usloviiam Tsentralńo-Evropeĭskikh stran.