title: Effect of neonatal gonadectomy on lymphocytes population and blast formation in aged rats.
abstract: In male rats gonadectomized at birth, the blast formation reaction of lymphocytes was significantly lower at 114 weeks of age, than that of non-gonadectomized controls, whereas the lymphocyte subpopulation was similar. The thymus of neonatally castrated rats of age 114 weeks was histologically normal, decreasing in weight of 68% of that of non-castrated rats.
authors.affiliation: Imamichi Institute for Animal Reproduction, Niihari, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Ikarashi
authors.forename: K
authors.initials: K
authors.lastname: Tauchi
authors.forename: M
authors.initials: M
authors.lastname: Yukawa
mesh_terms: D000375:Aging / Q000276:immunology*; D000818:Animals; D000831:Animals, Newborn; D016175:B-Lymphocyte Subsets / Q000276:immunology; D005434:Flow Cytometry; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D009919:Orchiectomy; D051381:Rats; D017208:Rats, Wistar; D012016:Reference Values; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013950:Thymus Gland / Q000254:growth & development / Q000276:immunology