Death rate and recurrence pattern among 841 clinical stage I endometrial cancer patients with special reference to uterine papillary serous carcinoma.
Eight hundred thirty-nine clinical stage I endometrial carcinoma patients diagnosed between 1979 and 1988 were treated at the University Hospital in Linköping. Forty-two (5%) had uterine papillary serous carcinoma of which 52% died of their disease. The recurrence rate, defined as new evidence of disease 6 months or more after termination of the initial treatment, was 31% among the UPSC patients compared to 6% in the non-UPSC group. The site of recurrence also differed significantly between the two groups, with the abdomen as the most common site among UPSC patients (46%) and the vagina (34%) among the ordinary adenocarcinoma patients. All UPSC patients with recurrence died of their malignancy compared to 61% of the ordinary adenocarcinoma patients. Ninety percent of isolated vaginal recurrences in ordinary adenocarcinoma patients (17) were diagnosed at a scheduled outpatient checkup. Of these, 13 are alive with no known disease after treatment.
Rosenberg
P
P
Department of Gynecologic Oncology, University Hospital, Linköping, Sweden.
Blom
R
R
Högberg
T
T
Simonsen
E
E
D000230:Adenocarcinoma / Q000453:epidemiology* / Q000401:mortality*; D018283:Cystadenocarcinoma, Papillary / Q000453:epidemiology* / Q000401:mortality*; D016889:Endometrial Neoplasms / Q000453:epidemiology* / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D009367:Neoplasm Staging; D012008:Recurrence; D015996:Survival Rate; D013548:Sweden / Q000453:epidemiology; D014594:Uterine Neoplasms / Q000453:epidemiology* / Q000401:mortality*