title: [Heparin-induced thrombocytopenia and vena cava filter. Difficulties of treatment].
abstract: The authors report two cases of thrombosis occurring after partial interruption of the inferior vena cava. They presented as collapse and anuria with fatal outcome. Heparin induced thrombocytopenia was present in two cases and distal migration of filter in one case. Thrombo-embolic complications can follow heparin induced thrombocytopenia and justify first treatment with low molecular weight heparin and/or early treatment with oral anti-coagulant. Thrombosis, recurrent embolism or thrombosis of renal vena may occur after vena cava filter. Renal vena thrombosis especially follow filter movement and present as collapse and cardiac failure often with fatal outcome.
authors.affiliation: Service de Médecine Interne B, Hôpital de Brabois, CHU Nancy, Vandoeuvre.
authors.forename: P
authors.initials: P
authors.lastname: Jouanny
authors.forename: C
authors.initials: C
authors.lastname: Jeandel
authors.forename: M C
authors.initials: MC
authors.lastname: Laurain
authors.forename: F
authors.initials: F
authors.lastname: Penin
authors.forename: G
authors.initials: G
authors.lastname: Cuny
mesh_terms: D000368:Aged; D017809:Fatal Outcome; D005260:Female; D005548:Foreign-Body Migration; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000628:therapy; D013927:Thrombosis / Q000209:etiology / Q000628:therapy; D016306:Vena Cava Filters / Q000009:adverse effects*
chemical_list: D006493:Heparin
vernacular_title: Thrombopénie à l'héparine et filtre cave. Difficultés du traitement.