title: Clinical profile of pediatric patients hospitalized with respiratory syncytial virus infection.
abstract: To update the clinical profile of pediatric patients hospitalized with RSV infection, we retrospectively reviewed the records of 246 children (male:female ratio 1.44:1) admitted during one season to a tertiary-care hospital. The most common admitting diagnoses were bronchiolitis (37.4%), pneumonia (32.5%), and possible septicemia (13%). Median age was 3 months; median length of stay, three days. Twice as many minorities were admitted with RSV infection as all other admissions during the same year. Family history of asthma, while common (35%), did not affect length of stay or complications. Of the 38 (15%) patients requiring intensive care, 29 (76%) underwent ventilation. Patients with underlying cardiopulmonary disease had more complications, were more likely to require intensive care (about 50%), and had significantly longer hospital stays than others. All three patients (1.2%) who died had congenital heart disease. Common risk factors included young age, chronic cardiopulmonary disease, male sex, and possibly family history of asthma. Although the most typical clinical diagnoses remain bronchiolitis and pneumonia, a systemic illness resembling the sepsis syndrome has emerged at our institution as a significant clinical presentation.
authors.affiliation: Department of Pediatrics, University of California, Irvine.
authors.forename: W V
authors.initials: WV
authors.lastname: La Via
authors.forename: S W
authors.initials: SW
authors.lastname: Grant
authors.forename: H R
authors.initials: HR
authors.lastname: Stutman
authors.forename: M I
authors.initials: MI
authors.lastname: Marks
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D001741:Black or African American; D001213:Asian; D001997:Bronchopulmonary Dysplasia / Q000453:epidemiology; D002140:California / Q000453:epidemiology; D005006:Ethnicity; D005260:Female; D006330:Heart Defects, Congenital / Q000453:epidemiology; D006630:Hispanic or Latino; D006760:Hospitalization / Q000706:statistics & numerical data*; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay / Q000706:statistics & numerical data; D015141:Los Angeles / Q000453:epidemiology; D008297:Male; D012121:Respiration, Artificial / Q000706:statistics & numerical data; D012136:Respiratory Syncytial Viruses; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000208:ethnology / Q000628:therapy; D010253:Respirovirus Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000208:ethnology / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors; D044465:White People
chemical_list: D000318:Adrenergic beta-Agonists