Sequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes.
Genes for MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamases have been cloned and sequenced. The gene for MGH-1 has the sequence of blaTEM-10, YOU-2 has that of blaTEM-12, and YOU-1 has that of blaTEM-26. All have evolved from blaTEM-1b but have the strong dual promoter sequence of blaTEM-2.
Rice
L B
LB
Department of Veterans Affairs Medical Center, Cleveland, Ohio.
Marshall
S H
SH
Carias
L L
LL
Sutton
L
L
Jacoby
G A
GA
D000595:Amino Acid Sequence; D003001:Cloning, Molecular; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
D001618:beta-Lactamases; C034413:beta-lactamase TEM-1; C056342:beta-lactamase TEM-2