title: [Eye-pressure tonometry in prevention of glaucoma].
abstract: Oculo-pression tonometry (OPT) was introduced in 1984 as a clinical method of examining ocular hydrodynamics. The method involves measuring intraocular pressure (IOP) by applanation tonometry performed before, during and after application of a pressure load that disturbs the dynamic balance between aqueous production and aqueous outflow. From the IOP before (P0) and immediately after (Pr0) the 8-min pressure load period, the outflow facility C(u) can be calculated: [formula: see text] The examinations performed so far have shown that (1) reduced outflow facility can be detected by OPT with a high degree of reliability, and (2) reduced outflow facility is always preceded by the development of glaucoma damage to the optic nerve head. A prospective study has shown that in the group of patients with reduced outflow facility but without glaucoma damage, 73% developed glaucoma damage with typical changes of the papilla and visual field within 3-7 years after the first examination.
authors.affiliation: Abteilung für Funktionsdiagnostik, Neuroophthalmologie und Experimentelle Ophthalmologie, Universitäts-Augenklinik Leipzig.
authors.forename: W D
authors.initials: WD
authors.lastname: Ulrich
authors.forename: C
authors.initials: C
authors.lastname: Ulrich
authors.forename: C
authors.initials: C
authors.lastname: Petzel
authors.forename: N
authors.initials: N
authors.lastname: Nenning
authors.forename: T
authors.initials: T
authors.lastname: Barth
mesh_terms: D004867:Equipment Design; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects / Q000502:physiology; D012016:Reference Values; D013999:Timolol / Q000008:administration & dosage; D014065:Tonometry, Ocular / Q000295:instrumentation*; D014794:Visual Fields / Q000187:drug effects / Q000502:physiology
chemical_list: D013999:Timolol
vernacular_title: Okulopressionstonometrie (OPT) in der Glaukompraxis.