title: Sinus histiocytosis with massive lymphadenopathy. Skeletal involvement.
abstract: A 64-year-old female patient has been suffering from sinus histiocytosis with massive lymphadenopathy (SHML) for 2 years. After 12 months of illness, the patient developed swelling and pain in various skeletal regions. Scintigraphic, radiological and CT imaging revealed multiple osseous lesions. Subsequent biopsies yielded the histomorphological findings typical for SHML. After operative resection of the left cuboid, which was the most painful region during walking, the defect was filled with an autologous bone transplant. At this time no other osteolytic region was treated surgically, because the patient had first to undergo ENT treatment.
authors.affiliation: Orthopedic Clinic of the Free University of Berlin at Oskar-Helene-Heim, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Lehnert
authors.forename: A
authors.initials: A
authors.lastname: Eisenschenk
authors.forename: D
authors.initials: D
authors.lastname: Dienemann
authors.forename: M
authors.initials: M
authors.lastname: Linnarz
mesh_terms: D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D005260:Female; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D011859:Radiography