Intracameral tissue plasminogen activator to treat blocked glaucoma implants.
I report the use of tissue plasminogen activator to open blocked silicone tubes of Baerveldt glaucoma implants in two cases. A dose of 25 micrograms was used in both cases; lysis of fibrin clots occurred within 15 to 45 minutes.
Richards
D W
DW
Department of Ophthalmology, University of South Florida College of Medicine, Tampa.
D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000601:surgery; D001777:Blood Coagulation / Q000187:drug effects*; D005260:Female; D005337:Fibrin / Q000187:drug effects; D005342:Fibrinolysis; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy*; D019736:Prostheses and Implants; D011994:Recombinant Proteins / Q000627:therapeutic use; D012826:Silicone Elastomers; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
D011994:Recombinant Proteins; D012826:Silicone Elastomers; D005337:Fibrin; D010959:Tissue Plasminogen Activator