Presynaptic modulation of spinal reflexes.
Recent evidence suggests that independent sets of interneurons mediate presynaptic inhibition of primary and secondary muscle spindles and of tendon organ afferents. There is also evidence that the information which flows through different intraspinal collaterals of a single muscle spindle or tendon organ afferent fiber is selectively affected by electrical stimulation of the motor cortex. These studies suggest that presynaptic inhibition plays an important role in the selection of the sensory signals required for the execution of a specific motor task.
Rudomin
P
P
Department of Physiology, Biophysics and Neurosciences, Centro de Investigación y de Estudios Avanzados, México DF, México.
Quevedo
J
J
Eguibar
J R
JR
D000818:Animals; D006801:Humans; D017661:Receptors, Presynaptic / Q000502:physiology*; D012018:Reflex / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*; D017833:Visceral Afferents / Q000502:physiology
D017661:Receptors, Presynaptic