[A stereological analysis of the tissue organization of the myocardium in long-term adaptation to alpine conditions].
Stereologic study of myocardium of Wistar rats after longterm living (during 10 months) at high altitude (at 3200 m above sea level) was carried out. It was shown that tissue reorganization of left ventricle myocardium under these conditions was characterized by significant decrease of the volume and surface densities of capillaries and endothelial cells, especially after living during 5 months in mountains. Simultaneously the processes of intracellular regeneration in cardiomyocytes were disordered, this manifesting as a rarity and lysis of sarcoplasm and also as atrophy of a part of cardiomyocytes. These changes were more pronounced after living during 10 months at high altitude.
Lushnikova
E L
EL
Mazhbich
B I
BI
Nepomniashchikh
L M
LM
D000222:Adaptation, Physiological; D000531:Altitude; D000532:Altitude Sickness / Q000473:pathology; D000818:Animals; D006332:Cardiomegaly / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D007707:Kyrgyzstan; D008297:Male; D009206:Myocardium / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
Stereologicheskiĭ analiz tkanevoĭ organizatsii miokarda pri dlitel'noĭ adaptatsii k usloviiam vysokogor'ia.