title: Effects of iron repletion on VO2max, endurance, and blood lactate in women.
abstract: To determine the effects of an 8-wk dietary iron supplementation (100 mg.d-1) on low plasma ferritin concentration (< 20 ng.ml-1) and endurance, 20 active women (19-35 yr) were studied while performing a VO2max test and an endurance test (80% VO2max) on a cycle ergometer. Subjects were randomly placed in an iron supplement (IG) or a placebo group (PG) using a double-blind method. After treatment in the IG, ferritin levels were higher (22.5 +/- 3.4 vs 14.3 +/- 2.2 ng.ml-1; P < 0.05), Hb increased (12.8 +/- 0.4 to 14.1 +/- 0.2 g.dl-1; P < 0.05), and TIBC decreased (366.2 +/- 24.8 to 293.8 +/- 14.0 micrograms.dl-1; P < 0.05). Also after treatment the IG's VO2max was significantly greater (P < 0.05) than the PG value and their postendurance blood lactate decreased (5.03 +/- 0.44 to 3.85 +/- 0.6 mM.l-1; P < 0.05). Endurance time to exhaustion increased 38% (37.28 +/- 5.03 to 51.4 +/- 7.45 min) following iron treatment; however, this change was not statistically significant. The results suggest that this level of iron supplementation can reverse mild anemia, increase VO2max, and reduce blood lactate concentration after submaximal exercise.
authors.affiliation: Department of Nutrition, Food and Movement Sciences, College of Human Sciences, Florida State University, Tallahassee 32306-2033.
authors.forename: J J
authors.initials: JJ
authors.lastname: LaManca
authors.forename: E M
authors.initials: EM
authors.lastname: Haymes
mesh_terms: D000293:Adolescent; D000328:Adult; D000747:Anemia, Hypochromic / Q000503:physiopathology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007501:Iron / Q000008:administration & dosage / Q000502:physiology*; D000090463:Iron Deficiencies; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D010101:Oxygen Consumption / Q000502:physiology*; D010807:Physical Endurance / Q000502:physiology*
chemical_list: D007773:Lactates; D019344:Lactic Acid; D007501:Iron