title: Effect of scrubbing and irrigation on staphylococcal and streptococcal counts in contaminated lacerations.
abstract: We studied the effects of scrubbing with poloxamer 188 (SCR), irrigating with povidone iodine (PI), and scrubbing followed by irrigation (SCR-PI) on staphylococcal and streptococcal counts in inoculated guinea pig lacerations. PI irrigation and SCR-PI significantly lowered streptococcal counts (P < 0.05). Staphylococcal counts were not different from those in controls.
authors.affiliation: Department of Emergency Medicine, Georgetown University Hospital, Washington, D.C. 20007-2197.
authors.forename: J M
authors.initials: JM
authors.lastname: Howell
authors.forename: H S
authors.initials: HS
authors.lastname: Dhindsa
authors.forename: T O
authors.initials: TO
authors.lastname: Stair
authors.forename: B A
authors.initials: BA
authors.lastname: Edwards
mesh_terms: D000818:Animals; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D004203:Disinfection; D006168:Guinea Pigs; D011060:Poloxalene / Q000494:pharmacology; D011206:Povidone-Iodine / Q000494:pharmacology; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D013211:Staphylococcus aureus / Q000187:drug effects; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D013297:Streptococcus pyogenes / Q000187:drug effects; D007507:Therapeutic Irrigation; D014946:Wound Infection / Q000188:drug therapy / Q000382:microbiology* / Q000628:therapy*
chemical_list: D011206:Povidone-Iodine; D011060:Poloxalene