title: Analysis of heavy metals in mouse uterine secretion by X-ray microanalysis.
abstract: A method for the detection of heavy metal ions in the uterine secretion of the mouse was tested. Mice received an intravenous injection of lead, and beads of an analytical grade resin, Chelex 100, were deposited in the uterine lumen to absorb heavy metals present in the secretion. X-ray microanalysis of the flushed beads showed that lead was present in a dose-related way in the uterine secretion of mice that had received 0.05, 0.1, or 0.15 mg lead per g body weight. Thus, the technique allows quantitative analysis of lead in the uterine secretion. The amount of lead present in the secretion decreased with time after the application of lead.
authors.affiliation: Department of Human Anatomy, University of Uppsala, Sweden.
authors.forename: Z
authors.initials: Z
authors.lastname: Jin
authors.forename: B O
authors.initials: BO
authors.lastname: Nilsson
mesh_terms: D000818:Animals; D002614:Chelating Agents; D004577:Electron Probe Microanalysis; D005260:Female; D066298:In Vitro Techniques; D007275:Injections, Intravenous; D007854:Lead / Q000378:metabolism* / Q000494:pharmacology; D051379:Mice; D008815:Mice, Inbred Strains; D008863:Microspheres; D009566:Nitrates / Q000494:pharmacology; D009994:Osmolar Concentration; D012117:Resins, Synthetic; D014599:Uterus / Q000378:metabolism*
chemical_list: D002614:Chelating Agents; D009566:Nitrates; D012117:Resins, Synthetic; C024997:Chelex 100; D007854:Lead; C017461:lead nitrate