[Intraoperative lymph nodes dissection guided by preoperative endoscopical injection of mitomycin C absorbed activated carbon (MMC-CH40) at pericancerous gastric mural in patients with gastric cancer].
22 patients with gastric cancer underwent preoperative endoscopical MMC-CH injection before radical resection. Lymph nodes resected in MMC-CH40 group averaged 47.0 vs. 28.1 in the control group (P < 0.05). Positive nodes were found 15 of 22 cases (68%) in MMC-CH40 group vs. 22 out of 26 cases (77%) in the control group (P > 0.05). Positive nodes totalled up to 166 of all 1033 dissected in the former (16%) vs. 162 of 730 (23%) in the latter (P < 0.01). Positive nodes found in 15 of 22 cases in MMC-CH40 group averaged 11.07 per lymph-node-metastasized patient vs. 7.36 in the control group (P < 0.01). The results showed that this procedure is of assistance to thorough dissection of lymph node during surgery.
Qi
X D
XD
First Affiliated Hospital, China Medical University, Shenyang.
D002606:Charcoal / Q000008:administration & dosage; D005773:Gastroscopy; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis; D016685:Mitomycin / Q000008:administration & dosage*; D010316:Particle Size; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*
D002606:Charcoal; D016685:Mitomycin