Influence of water and ethanol extracts of the oyster mushroom (Pleurotus ostreatus) on serum and liver lipids of the Syrian hamsters.
Extracts from the dried and ground fungus were prepared with water and with 30%, 60% and 85% ethanol, and thickened in vacuum. The whole fungus and extracts were added to the hyperlipidemic diet in amounts equivalent to 3% of the whole fungus. After 6 weeks the whole fungus, its water as well as 30% and 60% ethanol extracts have significantly reduced the contents of cholesterol (C) and triacylglycerols (TG) in the serum. The C and TG contents of the liver were reduced by 34-48% (in the case of TG insignificantly when applying the water and 60% ethanol extracts). The 85% ethanol extracts reduced the C and TG levels in both serum and liver statistically insignificantly by 18-22%. The reduction of serum C by addition of the whole fungus and its water and 30% ethanol extract was decisively affected by the reduction in the C contents in the very low density fraction of lipoproteins.
Bobek
P
P
Research Institute of Nutrition, Bratislava, Slovakia.
Ozdin
L
L
Kuniak
L
L
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D006224:Cricetinae; D004041:Dietary Fats / Q000008:administration & dosage; D000431:Ethanol; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D008099:Liver / Q000737:chemistry* / Q000187:drug effects; D008297:Male; D008647:Mesocricetus; D010936:Plant Extracts / Q000494:pharmacology; D011124:Polyporaceae / Q000737:chemistry*; D014867:Water
D004041:Dietary Fats; D008055:Lipids; D008074:Lipoproteins; D010936:Plant Extracts; D014867:Water; D000431:Ethanol; D002784:Cholesterol