title: [A case of giant condyloma acuminatum. On differential diagnosis of giant condylomas from Buschke-Löwenstein tumors and verrucous carcinoma].
abstract: We report on a 67-year-old man with a large papillomatous tumour of the penis clinically resembling verrucous carcinoma. HPV 6 and HPV 11 DNA could be isolated by hybridization techniques. The tumour showed exclusively exophytic growth with anastomosing acanthosis and papillomatosis. Groups of vacuolated cells were present in the spinous and granular layers. Endophytic and destructive proliferations and cytologic criteria of malignancy were absent. This tumor was a giant condyloma acuminatum and not either a Buschke-Löwenstein tumour or a verrucous carcinoma. There was no recurrence 2 years after local excision. The differential diagnosis of giant condylomas and Buschke-Löwenstein tumours is discussed.
authors.affiliation: Abteilung Allgemeine Dermatologie mit Schwerpunkt Histopathologie und Angiologie, Ruhr-Universität Bochum im St. Josef-Hospital.
authors.forename: H H
authors.initials: HH
authors.lastname: Niederauer
authors.forename: N
authors.initials: N
authors.lastname: Weindorf
authors.forename: U
authors.initials: U
authors.lastname: Schultz-Ehrenburg
mesh_terms: D000368:Aged; D018289:Carcinoma, Verrucous / Q000473:pathology* / Q000601:surgery; D003218:Condylomata Acuminata / Q000473:pathology* / Q000601:surgery; D004279:DNA, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D027383:Papillomaviridae / Q000302:isolation & purification; D030361:Papillomavirus Infections / Q000473:pathology* / Q000601:surgery; D010412:Penile Neoplasms / Q000473:pathology* / Q000601:surgery; D012867:Skin / Q000473:pathology; D014412:Tumor Virus Infections / Q000473:pathology* / Q000601:surgery
chemical_list: D004279:DNA, Viral
vernacular_title: Ein Fall von Condyloma acuminatum giganteum. Zur Differentialdiagnose der Riesenkondylome von den Buschke-Löwenstein-Tumoren und dem verrukösen Karzinom.