Ultrastructure of convoluted proximal tubule of kidney mice before and after X-ray exposure.
Ultrastructural initial changes study of convoluted proximal tubule after single dose of 154.8 mC/kg (600R), X-ray whole body radiation was performed in 12 C57BL mice. Twenty-four hours later, mitochondria evidenced proeminent changes such as cristolyses, dilatation and vacuolization. Within 72 hours, heterochromatin nuclei increased and vanished 144 hours after X-ray exposure. Such findings suggest that recovery probably happened because convoluted proximal tubules take place, regeneration occurs in a slow rate.
Enokihara
M M
MM
Escola Paulista de Medicina, São Paulo, Brasil.
Pacheco
I P
IP
Segreto
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HR
D000818:Animals; D007687:Kidney Tubules, Proximal / Q000528:radiation effects / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D011829:Radiation Dosage; D013997:Time Factors