[New test for detection of hypersensitivity to mycobacterial tuberculosis].
A new test for abnormal sensitization of the body with M. tuberculosis proposed by the authors implies conduction of leukocyte migration inhibition test under theophylline-induced block of T-suppressor function. Examination of 82 tuberculous patients and 30 healthy subjects proved high accuracy of the test able to identify the sensitization significantly, irrespective of the activity of T-cell suppressive population. The method is applicable also in latent tuberculosis, the detection of which permits earlier introduction of adequate therapy.
Batian
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Titov
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Batian
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D000328:Adult; D000368:Aged; D002464:Cell Migration Inhibition; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D015203:Reproducibility of Results; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D013806:Theophylline; D014376:Tuberculosis / Q000276:immunology*
D013806:Theophylline
Novyĭ test dlia opredeleniia povyshennoĭ sensibilizatsii organizma mikobakteriiami tuberkulëza.