Intravascular malignant lymphomatosis: amelioration of neurological symptoms with plasmapheresis.
Intravascular malignant lymphomatosis is a rare disease that is uniformly fatal when disseminated. Chemotherapeutic and radiation therapy regimens have provided short-term amelioration of symptoms but have not affected overall survival. We describe a patient with diffuse neurological symptoms who responded transiently but dramatically to plasmapheresis. This marked response warrants further evaluation of this therapy in intravascular malignant lymphomatosis.
Harris
C P
CP
Department of Pathology, University of Utah Medical Center, Salt Lake City.
Sigman
J D
JD
Jaeckle
K A
KA
D000328:Adult; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000628:therapy*; D009360:Neoplastic Cells, Circulating; D009423:Nervous System Neoplasms / Q000175:diagnosis / Q000628:therapy*; D010956:Plasmapheresis