Angiosarcoma, porphyria cutanea tarda, and probable chloracne in a worker exposed to waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
A worker developed angiosarcoma, porphyria cutanea tarda, and skin lesions characteristic of mild chloracne. About 10 years earlier he had been employed at a truck terminal in Saint Louis, Missouri, at a time when it was sprayed with waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The occurrence of these three rare conditions in a single exposed worker supports the aetiological relation between environmental exposure to TCDD and the subsequent development of soft tissue sarcoma and porphyria cutanea tarda.
McConnell
R
R
Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York 10029.
Anderson
K
K
Russell
W
W
Anderson
K E
KE
Clapp
R
R
Silbergeld
E K
EK
Landrigan
P J
PJ
D000152:Acne Vulgaris / Q000139:chemically induced*; D006394:Hemangiosarcoma / Q000139:chemically induced*; D006801:Humans; D007219:Industrial Oils; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure / Q000009:adverse effects*; D000072317:Polychlorinated Dibenzodioxins / Q000009:adverse effects*; D017119:Porphyria Cutanea Tarda / Q000139:chemically induced*; D013997:Time Factors; D015431:Weight Loss
D000072317:Polychlorinated Dibenzodioxins