[The technology for manufacturing antiparasitic preparations. 1. The development of a technology for producing the anthelmintic triklazan in finely dispersed form and the evaluation of its antinematodal, anticestodal and antitrematodal activities].
The authors describe the technology of preparing a new anthelmintic agent triclazan, N-(3,4-dichlorophenyl)-2-[(benzo-2,1,3-thiadiazole-4-sulfonyl)amino]-5- chlorobenzamide, finely dispersed (the particles size 4-8 mu). Triclazan is highly effective not only in hymenolepiasis and trichocephaliasis, as was shown previously, but in fascioliasis, monieziasis and intestinal nematodiasis of sheep as well.
Mikhaĭlitsyn
F S
FS
Petrov
Iu F
IuF
Smirnov
A A
AA
Drusviatskaia
S K
SK
Aleksandrov
A G
AG
Uvarova
N A
NA
Kazarin
A Iu
AIu
Lozlov
V N
VN
Bol'shakova
A Iu
AIu
D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage* / Q000138:chemical synthesis* / Q000737:chemistry; D002590:Cestode Infections / Q000188:drug therapy / Q000662:veterinary; D004353:Drug Evaluation, Preclinical; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary; D010316:Particle Size; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy; D013830:Thiadiazoles / Q000008:administration & dosage* / Q000138:chemical synthesis* / Q000737:chemistry; D014201:Trematode Infections / Q000188:drug therapy / Q000662:veterinary
D000871:Anthelmintics; D013830:Thiadiazoles; C086170:triclazan
Tekhnologiia proizvodstva protivoparazitarnykh preparatov. Soobshchenie 1. Razrabotka tekhnologii polucheniia antigel'mintika triklazana v melkodispersnoĭ forme i otsenka ego protivonematodnoĭ, protivotsestodnoĭ i protivotrematodnoĭ aktivnosti.