Scotopic threshold response and scotopic PII in glaucoma.
OBJECTIVE
The value of the ERG scotopic threshold response (STR), which is known to originate in the proximal retina and of the near-threshold scotopic PII(B-wave), was studied in glaucoma.


METHODS
Full-field single flashes were presented under scotopic conditions in two subject groups, a glaucoma group (n = 30) and a normal control group (n = 35). The intensity level for evoking STR was where the maximum response occurs, whereas the intensity level for evoking scotopic PII was where the response begins to appear.


RESULTS
The STR is only slightly reduced in glaucoma (P = 0.046), but scotopic PII is significantly diminished (P < 0.0001).


CONCLUSIONS
The relatively intact STR in glaucoma suggests that structures responsible for its generation are less damaged in glaucoma than those responsible for scotopic PII.
Korth
M
M
Department of Ophthalmology, University of Erlangen-Nürnberg, Germany.
Nguyen
N X
NX
Horn
F
F
Martus
P
P
D003623:Dark Adaptation / Q000502:physiology*; D004596:Electroretinography; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D010775:Photic Stimulation; D012684:Sensory Thresholds / Q000502:physiology*