title: Ultrastructural and morphometrical analyses of the brown adipocyte nucleus in a hibernating dormouse.
abstract: The fine morphology, size, and perichromatin granule frequency were analysed in brown adipocyte nuclei from hibernating, arousing, and euthermic dormice, Muscardinus avellanarius. Unusual nuclear structural constituents such as nuclear amorphous bodies, coiled body-like constituents and bundles of nucleoplasmic filaments were described as typical of hibernating nuclei. Morphometrical findings showed significant difference in total nuclear and nucleolar size in the three physiological conditions investigated as well as decreasing frequency of perichromatin granules in nuclei of hibernating to arousing to euthermic animals. A possible involvement of these granules in the intranuclear transport or storage of pre-mRNA is discussed in the context of other experimental evidence.
authors.affiliation: Center of Electron Microscopy, University of Lausanne, Switzerland.
authors.forename: C
authors.initials: C
authors.lastname: Zancanaro
authors.forename: M
authors.initials: M
authors.lastname: Malatesta
authors.forename: P
authors.initials: P
authors.lastname: Vogel
authors.forename: F
authors.initials: F
authors.lastname: Osculati
authors.forename: S
authors.initials: S
authors.lastname: Fakan
mesh_terms: D017667:Adipocytes / Q000648:ultrastructure*; D002001:Adipose Tissue, Brown / Q000648:ultrastructure*; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D006605:Hibernation / Q000502:physiology*; D012377:Rodentia / Q000033:anatomy & histology*