[Disorders of membrane mechanisms for regulating calcium homeostasis in cardiac arrhythmias in children].
Importance of calmodulin and Ca2+ in membranes of erythrocytes and myocardium was studied in children with ectopic forms of cardiac arrhythmia--extrasystole, paroxysmal and nonparoxysmal tachycardia. Activation of lipid peroxidation and shifts in cytomembrane phospholipid spectrum were shown to be involved in impairments of calcium homeostasis regulation, which is responsible for control of electromechanical parameters and may be related to deterioration of myocardial electrophysiological properties.
Bershova
T V
TV
Gordeeva
G F
GF
Vasil'eva
E M
EM
Bokeriia
L A
LA
Nam
R A
RA
Danilova
N V
NV
Serbin
V I
VI
D000293:Adolescent; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D002118:Calcium / Q000502:physiology*; D002147:Calmodulin / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D006706:Homeostasis; D006801:Humans; D015227:Lipid Peroxidation; D008563:Membrane Lipids / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism
D002147:Calmodulin; D008563:Membrane Lipids; D010743:Phospholipids; D002118:Calcium
Narushennia membrannykh mekhanizmov reguliatsii kal'tsievogo gomeostaza pri aritmiiakh serdtsa u deteĭ.