A dominant negative mutation in the alpha 1 (X) collagen gene produces spondylometaphyseal defects in mice.
Jacenko
O
O
Department of Anatomy and Cellular Biology, Harvard Medical School, Boston, Massachusetts 02115.
LuValle
P
P
Solum
K
K
Olsen
B R
BR
D000818:Animals; D001846:Bone Development / Q000235:genetics; D002356:Cartilage / Q000002:abnormalities; D003094:Collagen / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D017880:Limb Deformities, Congenital; D051379:Mice; D008810:Mice, Inbred C57BL; D008822:Mice, Transgenic; D010012:Osteogenesis / Q000235:genetics; D010641:Phenotype; D017384:Sequence Deletion; D013131:Spine / Q000002:abnormalities*
D003094:Collagen