title: [Clinical analysis of the outcome of pregnancy with chronic renal disease].
abstract: Seventy-six cases of pregnancy with chronic renal disease, from Jan. 1971 to April 1992, were analysed. According to the value of serum creatinine, these cases were divided into four groups, i.e. normal, mild, moderate and severe renal insufficiency. The pregnancy outcome in the first two groups was satisfactory and that in the moderate and severe groups were poor. The prognosis was even worse when it complicated by chronic hypertension. Among the last two groups, 78.8% cases had superimposed preeclampsia, and 24.2% had deteriorated renal function. The perinatal mortality rate was 121.2/1000. The results suggested that the prognosis for mother and maternity baby is closely related to mother's renal function and whether chronic hypertension is complicated preeclampsia is the direct factor resulting deterioration of renal function. It was considered that if serum creatinine > 132.6 mumol/L and complicated by chronic hypertension, pregnancy must be avoided. If renal function is deteriorating, pregnancy must be interrupted.
authors.affiliation: People's Hospital, Beijing Medical University.
authors.forename: S
authors.initials: S
authors.lastname: Qiu
mesh_terms: D000328:Adult; D005260:Female; D005921:Glomerulonephritis / Q000503:physiopathology*; D006801:Humans; D007677:Kidney Function Tests; D009404:Nephrotic Syndrome / Q000503:physiopathology; D007752:Obstetric Labor, Premature / Q000209:etiology; D011225:Pre-Eclampsia / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011256:Pregnancy Outcome; D011704:Pyelonephritis / Q000503:physiopathology