title: Uncommon applications for continuous spinal anesthesia.
abstract: The role that uncommon agents of antinociception, placed intrathecally, play in the control of nociceptive signal transmission in the spinal cord is described. Three specific agents are discussed in detail: baclofen, a gamma aminobutyric acid mimetic agent; clonidine, an alpha-2 agonist; and somatostatin, a neuroinhibitory peptide. In addition, the efficacy of using an implanted pump-catheter system for the long-term infusion of baclofen and octreotide, a somatostatin-like analog, is reviewed.
authors.affiliation: Department of Anesthesiology, University of Missouri at Kansas City/Saint Luke's Hospital of Kansas City.
authors.forename: E E
authors.initials: EE
authors.lastname: Fibuch
mesh_terms: D000775:Anesthesia, Spinal / Q000295:instrumentation / Q000379:methods*; D001418:Baclofen / Q000008:administration & dosage; D002408:Catheters, Indwelling; D003000:Clonidine / Q000008:administration & dosage; D006801:Humans; D007278:Injections, Spinal; D015282:Octreotide / Q000008:administration & dosage
chemical_list: D001418:Baclofen; D003000:Clonidine; D015282:Octreotide