title: Influence of water and ethanol extracts of the oyster mushroom (Pleurotus ostreatus) on serum and liver lipids of the Syrian hamsters.
abstract: Extracts from the dried and ground fungus were prepared with water and with 30%, 60% and 85% ethanol, and thickened in vacuum. The whole fungus and extracts were added to the hyperlipidemic diet in amounts equivalent to 3% of the whole fungus. After 6 weeks the whole fungus, its water as well as 30% and 60% ethanol extracts have significantly reduced the contents of cholesterol (C) and triacylglycerols (TG) in the serum. The C and TG contents of the liver were reduced by 34-48% (in the case of TG insignificantly when applying the water and 60% ethanol extracts). The 85% ethanol extracts reduced the C and TG levels in both serum and liver statistically insignificantly by 18-22%. The reduction of serum C by addition of the whole fungus and its water and 30% ethanol extract was decisively affected by the reduction in the C contents in the very low density fraction of lipoproteins.
authors.affiliation: Research Institute of Nutrition, Bratislava, Slovakia.
authors.forename: P
authors.initials: P
authors.lastname: Bobek
authors.forename: L
authors.initials: L
authors.lastname: Ozdin
authors.forename: L
authors.initials: L
authors.lastname: Kuniak
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D006224:Cricetinae; D004041:Dietary Fats / Q000008:administration & dosage; D000431:Ethanol; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D008099:Liver / Q000737:chemistry* / Q000187:drug effects; D008297:Male; D008647:Mesocricetus; D010936:Plant Extracts / Q000494:pharmacology; D011124:Polyporaceae / Q000737:chemistry*; D014867:Water
chemical_list: D004041:Dietary Fats; D008055:Lipids; D008074:Lipoproteins; D010936:Plant Extracts; D014867:Water; D000431:Ethanol; D002784:Cholesterol