Spontaneous globoid mineralization in the cerebellum of rats.
Cerebellar globoid mineralization in two rats was examined by light and electron microscopy, and by X-ray microanalysis. The mineralization was round to oval in shape; it varied in size and was positive for the periodic acid-Schiff and von Kossa reactions. Ultrastructurally, a concentric lamellar structure was prominent in moderately electron-dense depositions. Elemental analysis revealed the presence of large amounts of calcium and phosphorus, and small amounts of zinc, potassium and aluminum.
Yanai
T
T
Department of Veterinary Pathology, Faculty of Agriculture, Gifu University, Japan.
Masegi
T
T
Ueda
K
K
Manabe
J
J
Teranishi
M
M
Takaoka
M
M
Matsunuma
N
N
Fukuda
K
K
Goto
N
N
D000818:Animals; D002118:Calcium / Q000032:analysis; D002531:Cerebellum / Q000737:chemistry* / Q000000981:diagnostic imaging; D004577:Electron Probe Microanalysis / Q000662:veterinary; D005260:Female; D008297:Male; D008854:Microscopy, Electron / Q000662:veterinary; D008903:Minerals / Q000032:analysis*; D010758:Phosphorus / Q000032:analysis; D011859:Radiography; D051381:Rats; D011916:Rats, Inbred F344
D008903:Minerals; D010758:Phosphorus; D002118:Calcium