Gamma Knife thalamotomy and pallidotomy in patients with movement disorders: preliminary results.
The Leksell Gamma Knife is a useful and safe method to perform thalamotomy and pallidotomy in selected older patients with Parkinson's disease and related movement disorders. In this preliminary report, 2 of 3 patients with severe intention tremor were relieved of their symptoms by thalamotomy, as were 4 of 7 patients with Parkinson's tremor. Four of 8 patients had significant improvement of contralateral rigidity following pallidotomy.
Rand
R W
RW
Neurosciences Institute, Hospital of the Good Samaritan, Los Angeles, Calif.
Jacques
D B
DB
Melbye
R W
RW
Copcutt
B G
BG
Fisher
M R
MR
Levenick
M N
MN
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005917:Globus Pallidus / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009127:Muscle Rigidity / Q000473:pathology / Q000601:surgery; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000473:pathology / Q000601:surgery*; D010302:Parkinson Disease, Secondary / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000473:pathology; D016634:Radiosurgery / Q000379:methods*; D013788:Thalamus / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D014202:Tremor / Q000473:pathology / Q000601:surgery