title: [Effects of replenishing kidney herbs on estrogen and 1,25-dihydroxyvitamin D3 of dexamethasone-induced rats model with osteoporosis].
abstract: Estrogen and 1,25-(OH)2-D3 change in rats with osteoporosis induced by dexamethasone (DXM) was observed. The calcium and replenishing Kidney Herbs (RKH) was used in treating osteoporosis. The results shown: The level of estrogen and 1,25-(OH)2-D3 in rats with osteoporosis was lower than that of the normal. Calcium and RKH were effective in treating osteoporosis and they could recover the level of estrogen and 1,25-(OH)2-D3 to normal state, the effect of RKH was better than that of calcium. There was positive correlation between the level of estrogen and 1,25-(OH)2-D3. The treatment of RKH might be an optimal method for osteoporotic treatment.
authors.affiliation: Dept. of Biochemistry, Hebei Medical College, Shijiazhuang.
authors.forename: H D
authors.initials: HD
authors.lastname: Liu
authors.forename: E
authors.initials: E
authors.lastname: Li
authors.forename: X X
authors.initials: XX
authors.lastname: Tong
mesh_terms: D000818:Animals; D002117:Calcitriol / Q000097:blood*; D002118:Calcium / Q000627:therapeutic use; D003907:Dexamethasone; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004958:Estradiol / Q000097:blood*; D005260:Female; D010024:Osteoporosis / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004365:Drugs, Chinese Herbal; D004958:Estradiol; D003907:Dexamethasone; D002117:Calcitriol; D002118:Calcium