title: Elevated levels of soluble CD54 (ICAM-1) in human immunodeficiency virus infection.
abstract: Soluble CD54 levels in sera were quantitated in asymptomatic intravenous drug users, homosexuals, and patients with lymphadenopathy, AIDS-related complex, or acquired immunodeficiency syndrome. Soluble CD54 levels were elevated in human immunodeficiency virus (HIV)-seronegative asymptomatic intravenous drug users, reflecting infections like cytomegalovirus, Epstein-Barr virus, and hepatitis B virus. The sera of human immunodeficiency virus-seropositive groups of patients also had elevated levels of soluble CD54, reflecting infections like cytomegalovirus and human immunodeficiency virus infection.
authors.affiliation: R.A. Cooke Institute of Allergy, St. Luke's-Roosevelt Hospital Center, New York, New York 10019.
authors.forename: M M
authors.initials: MM
authors.lastname: Reddy
authors.forename: M H
authors.initials: MH
authors.lastname: Grieco
mesh_terms: D015704:CD4 Antigens / Q000032:analysis; D016827:CD8 Antigens / Q000032:analysis; D015815:Cell Adhesion Molecules / Q000097:blood* / Q000502:physiology; D015658:HIV Infections / Q000097:blood*; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
chemical_list: D015704:CD4 Antigens; D016827:CD8 Antigens; D015815:Cell Adhesion Molecules; D014409:Tumor Necrosis Factor-alpha; D018799:Intercellular Adhesion Molecule-1