Multiple/heterogeneous Ca2+ stores in cerebellum Purkinje neurons.
1. The rapid and transient redistribution of Ca2+ from intracellular membrane-bound compartments (stores) is a key event of cell activation. 2. The cytological nature and molecular composition of such Ca2+ stores have been the object of intense investigation in recent years. 3. Here we review: (a) the current knowledge on intracellular Ca2+ stores of Purkinje neurons at the functional, biochemical, molecular, morphological and ultrastructural level; and discuss: (b) the relationship between Ca2+ stores and the endoplasmic reticulum, and (c) the occurrence of multiple/heterogeneous Ca2+ stores.
Volpe
P
P
Centro di Studio per la Biologia e Fisiopatologia Muscolare del CNR, Università di Padova, Italy.
Nori
A
A
Martini
A
A
Sacchetto
R
R
Villa
A
A
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000378:metabolism; D011689:Purkinje Cells / Q000378:metabolism* / Q000648:ultrastructure
D002118:Calcium