The results of 9 years of experience with a combined treatment with LH-RH and HCG for cryptorchidism.
During a period of time between 1984 and 1986, 79 boys with 91 cryptorchid testes were treated with a therapy which combined a LH-RH nasal spray followed by HCG. Kryptocur (LH-RH) was administered as a nasal spray at a dosage of 1.2 micrograms daily for a period of 14 days. HCG was injected intramuscularly, 5 times at 2-day intervals. The dosage was one-half the amount recommended by the WHF. This particular therapeutic strategy was more efficacious than those used previously. During the follow-up seven years later, 50.5% of the testes were in a scrotal position. The results during a five year follow-up of a second study were similar to those observed in the earlier study: 67% of the cryptorchid testes were in the scrotum.
Waldschmidt
J
J
Department of Pediatric Surgery, Klinikum Steglitz, Freie Universität Berlin, Germany.
Doede
T
T
Vygen
I
I
D000281:Administration, Intranasal; D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003456:Cryptorchidism / Q000188:drug therapy* / Q000601:surgery; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome
D006063:Chorionic Gonadotropin; D007987:Gonadotropin-Releasing Hormone