[Secondary immunodeficiencies in the pathogenesis of protracted forms of intestinal infections and the prospects for their immunocorrection].
Acute intestinal infections (AII) are characterized by marked defects of immune homeostasis. These were not related to the disease etiology though depended on the infection severity and manifested with T-lymphopenia, reduced count of circulating T-helper cells in normal amount of T-suppressor cells. This resulted in low immunoregulatory index (CD-4/CD-8). Immunological criteria have been determined indicative of the tendency to formation of a protracted AII course and long-term persistence of the agent in the host.
Iushchuk
N D
ND
Frolov
V M
VM
Peresadin
N A
NA
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D007410:Intestinal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D008297:Male; D008875:Middle Aged
D000276:Adjuvants, Immunologic
Vtorichnye immunodefitsity v patogeneze zatiazhnykh form kishechnykh infektsiĭ i perspektivy ikh immunokorrektsii.