Auditory reflex thresholds elevated by stress-induced cortisol secretion.
To study steroid effects on auditory perception, 24 volunteers were unexpectedly confronted with a psychological stressor. Auditory reflexes to pure tones and noise were recorded before stress exposure, up to 100 min afterwards and in a second control session. Repeated measurements of cortisol and testosterone in saliva, as well as blood pressure, heart rate, and subjective feelings confirmed the stressful nature of the test. Following stress induction the auditory reflex of the contralateral ear needed significantly higher loudness (i.e. more decibels) to be elicited than at baseline or control measures. Two lines of evidence suggest that this stress-induced change may be specifically related to glucocorticoid actions: (1) In a previous study similar elevations in auditory reflex threshold had been obtained by the administration of exogenous glucocorticoids (hydrocortisone), and (2) in the present study the overall effect of stress induction on acoustic reflex described above was mainly observed in a subgroup of subjects, who responded to the stressor with a marked rise in free cortisol.
Fehm-Wolfsdorf
G
G
Institute of Psychology, University of Kiel, Germany.
Soherr
U
U
Arndt
R
R
Kern
W
W
Fehm
H L
HL
Nagel
D
D
D000161:Acoustic Stimulation; D000328:Adult; D001143:Arousal / Q000502:physiology*; D001309:Auditory Threshold / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D008297:Male; D012022:Reflex, Acoustic / Q000502:physiology*; D012463:Saliva / Q000378:metabolism; D012931:Social Environment; D013315:Stress, Psychological / Q000150:complications*; D013739:Testosterone / Q000378:metabolism
D013739:Testosterone; D006854:Hydrocortisone