title: [Hemostatic changes in patients with tumors of the maxillofacial area].
abstract: To study hemostatic impairments in patients with maxillofacial tumors, 131 patients and 30 healthy subjects were examined. The patients were found to develop early hemostatic changes which appeared as a latent DIC syndrome. The mobility of the physiological system of PASA permits the equilibrium of coagulative and anticoagulative mechanisms to be preserved to a definite extent and fairly long. The changes were detected during the formation of prothrombinase, thrombin and during fibrin formation and stabilization in the fibrinolytic system. Hypercoagulation typical of the DIC syndrome at the early stages of tumor was followed by consumption coagulopathic signs and profuse bleeding risk at the T4 and N3 stages.
authors.forename: L P
authors.initials: LP
authors.lastname: Egorova
authors.forename: N N
authors.initials: NN
authors.lastname: Petrishchev
authors.forename: A I
authors.initials: AI
authors.lastname: Kirsanov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001780:Blood Coagulation Tests; D004211:Disseminated Intravascular Coagulation / Q000097:blood; D005153:Facial Neoplasms / Q000097:blood*; D005260:Female; D006487:Hemostasis; D006801:Humans; D007573:Jaw Neoplasms / Q000097:blood*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged
vernacular_title: Izmeneniia gemostaza u bol'nykh s opukholiami cheliustno-litsevoĭ oblasti.