Tuberculosis presenting as acute hepatitis in a renal transplant recipient.
We observed a kidney transplant recipient in whom acute hepatitis was the initial manifestation of tuberculosis, preceding radiological lung involvement by several weeks. The diagnosis was suspected and treatment initiated based on the finding of a granulomatous hepatitis on liver biopsy. Mycobacterial tuberculosis was grown and identified first in liver samples and only later in sputum and bone marrow. This case illustrates the protean manifestations of tuberculosis in immunosuppressed patients.
Mat
O
O
Department of Nephrology, Dialysis and Transplantation, Hôpital Erasme, Brussels, Belgium.
Abramowicz
D
D
Peny
M O
MO
Struelens
M
M
Doutrelepont
J M
JM
Adler
M
M
De Pauw
L
L
Vanherweghem
J L
JL
Kinnaert
P
P
Vereerstraeten
P
P
D000208:Acute Disease; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006509:Hepatitis B / Q000175:diagnosis* / Q000276:immunology; D006526:Hepatitis C / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology
D000995:Antitubercular Agents