title: Solitary fibrous tumor of the orbit.
abstract: We report three cases of an orbital soft tissue lesion that fulfills the histologic, immunohistochemical, and electron microscopic criteria for solitary fibrous tumor, an entity previously described as a pleural tumor, but recently reported to occur in other locations. All three patients presented with proptosis. Two of the patients were cured by simple excision, and one patient had two recurrences, the last recurrence incompletely excised. The findings indicate that solitary fibrous tumor can occur in the orbit and, like solitary fibrous tumors of other anatomic sites, may behave in a nonaggressive or occasionally, locally aggressive fashion, with as yet no metastatic potential demonstrated in orbital lesions.
authors.affiliation: Department of Pathology, Harvard Medical School, Boston, MA.
authors.forename: D M
authors.initials: DM
authors.lastname: Dorfman
authors.forename: K
authors.initials: K
authors.lastname: To
authors.forename: G R
authors.initials: GR
authors.lastname: Dickersin
authors.forename: A E
authors.initials: AE
authors.lastname: Rosenberg
authors.forename: B Z
authors.initials: BZ
authors.lastname: Pilch
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D000368:Aged; D003893:Desmin / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D003893:Desmin; D014746:Vimentin