Cerebral pericytes--a second line of defense in controlling blood-brain barrier peptide metabolism.
The above data clearly indicate that cerebral pericytes are equipped with a specific aminopeptidase (AP-N). Functionally, this finding suggests that cerebral pericytes are involved in amino acid and peptide catabolism of the brain and that they constitute an essential carrier of the enzymatic blood-brain barrier.
Krause
D
D
Institute of Anatomy, University of Regensburg, Germany.
Kunz
J
J
Dermietzel
R
R
D000626:Aminopeptidases / Q000378:metabolism; D000818:Animals; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D001812:Blood-Brain Barrier / Q000502:physiology*; D001921:Brain / Q000098:blood supply*; D018826:CD13 Antigens; D066298:In Vitro Techniques; D008833:Microcirculation / Q000166:cytology / Q000276:immunology / Q000502:physiology; D051381:Rats
D000911:Antibodies, Monoclonal; D000626:Aminopeptidases; D018826:CD13 Antigens