title: Changing patterns of microbial contamination and antimicrobial sensitivity in donor eyes.
abstract: Contaminating microbial flora and their in vitro antibiotic sensitivity pattern was determined for 1557 eyes from donor cadavers collected during five years. Positive cultures were obtained in 42.77% of the eyes; bacterial growth was observed in 39.17% of the eyes and fungal growth, in 3.6%. There was significant variation in the rate of contamination from year to year during the study period. Staphylococcus albus was the most frequently isolated organism (28.10%), followed by Acinetobacter spp., Pseudomonas aeruginosa, and Alcaligenes faecalis, respectively. Most of the organisms were resistant to commonly used antibiotics with a low weighted index of effectiveness, particularly toward gentamicin (resistance, 50.82%). The findings were compared with previous data from the same eye bank, and the variations are discussed.
authors.affiliation: Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi.
authors.forename: G
authors.initials: G
authors.lastname: Satpathy
authors.forename: S K
authors.initials: SK
authors.lastname: Angra
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D004352:Drug Resistance, Microbial; D005123:Eye / Q000382:microbiology*; D005125:Eye Banks; D005658:Fungi / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D014019:Tissue Donors
chemical_list: D000900:Anti-Bacterial Agents