[The characteristics of the antigenic and cytotropic properties of free subunits of the C-reactive protein].
A simple method of preparation of functionally active subunits of C-reactive protein (CRP) is described. Antigenic and biological properties of CRP and its subunits were compared. CRP subunits are shown to differ from the native CRP molecule by antigenicity and mitogenicity. Simultaneously, their capacity to activate human blood phagocytes increases.
Nazarov
P G
PG
Polevshchikov
A V
AV
Berestovaia
L K
LK
Petrov
I V
IV
Ponomarenko
V V
VV
D000818:Animals; D000941:Antigens / Q000276:immunology*; D002097:C-Reactive Protein / Q000276:immunology* / Q000302:isolation & purification / Q000494:pharmacology*; D003429:Cross Reactions; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D008934:Mitogens / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects / Q000378:metabolism; D010446:Peptide Fragments / Q000276:immunology* / Q000302:isolation & purification / Q000494:pharmacology*; D011817:Rabbits; D016897:Respiratory Burst / Q000187:drug effects
D000941:Antigens; D008934:Mitogens; D010446:Peptide Fragments; D002097:C-Reactive Protein
Kharakteristika antigennykh i tsitotropnykh svoĭstv svobodnykh sub''edinits C-reaktivnogo belka.