Effect of scrubbing and irrigation on staphylococcal and streptococcal counts in contaminated lacerations.
We studied the effects of scrubbing with poloxamer 188 (SCR), irrigating with povidone iodine (PI), and scrubbing followed by irrigation (SCR-PI) on staphylococcal and streptococcal counts in inoculated guinea pig lacerations. PI irrigation and SCR-PI significantly lowered streptococcal counts (P < 0.05). Staphylococcal counts were not different from those in controls.
Howell
J M
JM
Department of Emergency Medicine, Georgetown University Hospital, Washington, D.C. 20007-2197.
Dhindsa
H S
HS
Stair
T O
TO
Edwards
B A
BA
D000818:Animals; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D004203:Disinfection; D006168:Guinea Pigs; D011060:Poloxalene / Q000494:pharmacology; D011206:Povidone-Iodine / Q000494:pharmacology; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D013211:Staphylococcus aureus / Q000187:drug effects; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000628:therapy*; D013297:Streptococcus pyogenes / Q000187:drug effects; D007507:Therapeutic Irrigation; D014946:Wound Infection / Q000188:drug therapy / Q000382:microbiology* / Q000628:therapy*
D011206:Povidone-Iodine; D011060:Poloxalene