title: Isotope bone scanning for acute osteomyelitis and septic arthritis in children.
abstract: We prospectively studied 86 children to assess the value and accuracy of isotope bone scanning in the diagnosis of suspected acute haematogenous osteomyelitis and septic arthritis. The patients were scanned because of difficulty in localising the exact site of the pathology. Characteristic scan appearances were found. In osteomyelitis there was increased or decreased uptake extending beyond the confines of the joint capsule; in septic arthritis there was increased or decreased uptake on either side of the joint line, but largely limited to and uniform within the joint capsule. The bone-scan images were correlated with the final diagnosis in 34 sites of septic arthritis and in 62 sites of osteomyelitis. The overall accuracy of the bone scans was 81%. The predictive value for a positive scan to be correct was 100% for a cold scan and 82% for a hot scan. The main reason for a false-positive scan was contiguous soft-tissue infection. The predictive value for a negative scan to be correct was 63%. One reason for a false-negative scan was that the patient was in the transitional phase from cold to hot.
authors.affiliation: Department of Nuclear Medicine, University of Cape Town Medical School, Republic of South Africa.
authors.forename: C E
authors.initials: CE
authors.lastname: Tuson
authors.forename: E B
authors.initials: EB
authors.lastname: Hoffman
authors.forename: M D
authors.initials: MD
authors.lastname: Mann
mesh_terms: D000293:Adolescent; D001170:Arthritis, Infectious / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010019:Osteomyelitis / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011859:Radiography; D011877:Radionuclide Imaging; D015203:Reproducibility of Results; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate