[Clinical types of adrenoleukodystrophy].
With gas chromatography, we established a method of determining plasma very long-chain fatty acids (VLCFA). Eight cases with adrenoleukodystrophy (ALD) were confirmed by using plasma VLCFA assay as the diagnostic method. The phenotypes of the 8 patients are as follows: 1. Childhood ALD; 2. Adolescent ALD; 3. Adult cerebral ALD: 4. Adrenomyeloneuropathy; 5. Addison's disease without neurologic involvement; 6. Asymptomatic ALD. We do not agree with Moser's classification of ALD as presymptomatic and asymptomatic, but would suggest to have a subclinical type of ALD.
Wang
Y J
YJ
Department of Neurology, Xuanwu Hospital, Beijing.
Tian
M T
MT
Pang
S Q
SQ
D000293:Adolescent; D000326:Adrenoleukodystrophy / Q000145:classification* / Q000175:diagnosis; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002849:Chromatography, Gas; D005227:Fatty Acids / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male
D005227:Fatty Acids