title: Histopathologic evidence for cardiomyopathy in a child with mitral valve prolapse.
abstract: An intriguing relationship between idiopathic mitral valve prolapse (MVP) and cardiomyopathy has been reported in adult cases of MVP. This paper reports a girl with idiopathic MVP, who presented with progressive cardiomegaly and cardiomyopathic findings or, cardiac biopsy; right ventricular endomyocardial biopsy at the age of 15 years showed myocardial hypertrophy, disarray, myocardial degeneration, interstitial fibrosis and endocardial thickening. To our knowledge, this is the first case of idiopathic MVP in childhood that has been shown to have positive biopsy findings for cardiomyopathy.
authors.affiliation: Department of Pediatrics, Aomori Prefectural Central Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nakada
authors.forename: S
authors.initials: S
authors.lastname: Yonesaka
mesh_terms: D001706:Biopsy; D009202:Cardiomyopathies / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D004452:Echocardiography; D005260:Female; D006801:Humans; D008945:Mitral Valve Prolapse / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011379:Prognosis