Carcinosarcoma of the spleen. An extragenital malignant mixed müllerian tumor?
A 55-year-old woman with painful splenomegaly underwent surgical exploration and resection of the spleen. Pathologic examination revealed a neoplasm of the spleen exhibiting malignant stromal and epithelial components with müllerian features. In the absence of a recognized neoplasm elsewhere, the carcinosarcoma most likely arose as a primary splenic tumor and may represent an extrauterine malignant mixed müllerian tumor arising in the spleen.
Westra
W H
WH
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
Anderson
B O
BO
Klimstra
D S
DS
D002296:Carcinosarcoma / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D018200:Mixed Tumor, Mullerian / Q000150:complications / Q000473:pathology*; D013154:Spleen / Q000473:pathology; D013160:Splenic Neoplasms / Q000150:complications / Q000473:pathology*; D013163:Splenomegaly / Q000209:etiology