title: Gd-DTPA enhanced MRI of reactive hematopoietic regions in marrow.
abstract: OBJECTIVE
  The purpose of this report was to study the contrast enhancement of reactive hematopoietic regions in bone marrow on Gd-diethylenetriamine pentaacetic acid (DTPA) enhanced MRI.
  
  
  METHODS
  We compared the contrast enhancement of reactive hematopoietic regions in the marrow of patients with aplastic anemia and drug-induced pancytopenia and that of normal bone marrow on Gd-DTPA enhanced MRI.
  
  
  RESULTS
  The reactive hematopoietic marrow observed in aplastic anemia of moderate grade and drug-induced pancytopenia markedly enhanced after Gd-DTPA administration; normoplastic marrow showed no enhancement.
  
  
  CONCLUSIONS
  Gd-DTPA enhanced MRI was useful in detecting the reactive hematopoietic regions in bone marrow.
authors.affiliation: Department of Radiology, Nippon Medical School, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Amano
authors.forename: H
authors.initials: H
authors.lastname: Hayashi
authors.forename: T
authors.initials: T
authors.lastname: Kumazaki
mesh_terms: D000328:Adult; D000741:Anemia, Aplastic / Q000175:diagnosis / Q000473:pathology; D001853:Bone Marrow / Q000033:anatomy & histology* / Q000502:physiology; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006410:Hematopoiesis / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010198:Pancytopenia / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D004369:Pentetic Acid / Q000031:analogs & derivatives*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA