title: [The effect of strophanthidin acetate on the hemodynamic indices in children with cardiovascular insufficiency].
abstract: Hemodynamic properties of strophanthidine acetate have been assessed in children with II to III degree cardiovascular failure aged 1 to 14 years. The effect of the cardiac glycoside on central hemodynamic parameters has been assessed by the findings of ECG, impedance plethysmography, and phase analysis of the left ventricular systole. The onset of a negative chronotropic and a positive inotropic effect at the first minute after the drug administration has been revealed. The maximum effect was registered at the 15th minute and lasted for 60 minutes. Thus, a prompt development of a cardiotropic effect makes strophanthidine acetate the most beneficial agent for the treatment of acute heart failure in children.
authors.forename: T S
authors.initials: TS
authors.lastname: Agzamkhodzhaev
authors.forename: A E
authors.initials: AE
authors.lastname: Gorbunov
authors.forename: Sh M
authors.initials: ShM
authors.lastname: Takhirov
authors.forename: L E
authors.initials: LE
authors.lastname: Azizova
mesh_terms: D000293:Adolescent; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D013327:Strophanthidin / Q000627:therapeutic use*
chemical_list: D013327:Strophanthidin
vernacular_title: Vliianie strofantidina atsetata na pokazateli gemodinamiki u deteĭ s serdechno-sosudistoĭ nedostatichnostíu.