title: Frequency of seafood intake in pregnancy as a determinant of birth weight: evidence for a dose dependent relationship.
abstract: OBJECTIVE
  The aim was to explore whether maternal consumption of seafood is a determinant of birth weight in a dose dependent manner.
  
  
  METHODS
  A population based survey of lifestyle factors in pregnancy was linked with information from antenatal and obstetric records.
  
  
  METHODS
  Seventy five per cent of all 1362 women who delivered in the Faroe Islands during the study period 1986-87 who gave a structured post partum interview on lifestyle factors.
  
  
  RESULTS
  Altogether, 2, 6, 16, 33, 26, 14, and 3% of women had consumed approximately 0, 1, 2, 3, 4, 5, and 6+ respectively seafood (fish or whale) dinner meals per week during pregnancy. The average birth weight (p = 0.02) and birth length (p = 0.002) varied significantly between the seven groups, and increased by about 0.2 kg and 1 cm, respectively between women who ate 0 and those who consumed 3 seafood meals per week. Mean birth weight and length tended to level off with further fish consumption: when fitting a second degree polynomial, the quadratic terms were negative and significant for both birth weight (p = 0.005) and length (p = 0.001). Analogous analyses for pregnancy duration were not significant, but exhibited similar trends. All analyses were adjusted for maternal height, weight, parity, age, marital status, and smoking.
  
  
  CONCLUSIONS
  The weight and length of the newborn increased with the frequency of seafood dinner meals consumed in pregnancy but only up to a consumption level of about 3 meals per week.
authors.affiliation: Institute of Epidemiology and Social Medicine, University of Aarhus, Denmark.
authors.forename: S F
authors.initials: SF
authors.lastname: Olsen
authors.forename: P
authors.initials: P
authors.lastname: Grandjean
authors.forename: P
authors.initials: P
authors.lastname: Weihe
authors.forename: T
authors.initials: T
authors.lastname: Viderø
mesh_terms: D001724:Birth Weight / Q000502:physiology*; D001827:Body Height / Q000502:physiology; D015331:Cohort Studies; D004032:Diet; D005260:Female; D005865:Gestational Age; D006801:Humans; D009929:Organ Size / Q000502:physiology; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy / Q000502:physiology*; D017747:Seafood