Dermatophytes on the feet of HIV-infected patients: frequency, species distribution, localization and antimicrobial susceptibility.
Skin scrapings from the toe clefts, soles and nail plates of 138 HIV-infected patients at various stages were examined for the presence of dermatophytes using both microscopy and culture. Dermatophytes, in particular Trichophyton rubrum, could be grown in 58 cases (42%). Although cultures were more often positive in late stages of disease, there was no close correlation with the clinical stage or the T4/T8 ratio. Susceptibility to itraconazole, but not to other antimycotics, was correlated with the immune status (P < 0.05). Pedal dermatophyte infection does not seem to be a major problem in HIV infection.
Korting
H C
HC
Department of Dermatology, Ludwigs-Maximilians-University, Munich, Germany.
Blecher
P
P
Stallmann
D
D
Hamm
G
G
D000328:Adult; D016516:CD4-CD8 Ratio / Q000187:drug effects; D003881:Dermatomycoses / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D005528:Foot / Q000382:microbiology*; D005533:Foot Dermatoses / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D006118:Griseofulvin / Q000494:pharmacology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007121:Immunocompetence; D017964:Itraconazole / Q000494:pharmacology; D007654:Ketoconazole / Q000494:pharmacology; D008297:Male; D008826:Microbial Sensitivity Tests; D014249:Trichophyton / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification
D017964:Itraconazole; D006118:Griseofulvin; D007654:Ketoconazole