Postmortem drug analysis of meconium in early-gestation human fetuses exposed to cocaine: clinical implications.
Postmortem analysis of meconium from three human fetuses exposed to cocaine demonstrated the presence of cocaine in the meconium of a 17-week-old fetus and evidence that the concentration of cocaine in meconium is related to the amount and time of cocaine use by the mother during pregnancy. The latter observation was confirmed in a rat model.
Ostrea
E M
EM
Department of Pediatrics, Hutzel Hospital, Detroit, MI 48201.
Romero
A
A
Knapp
D K
DK
Ostrea
A R
AR
Lucena
J E
JE
Utarnachitt
R B
RB
D000818:Animals; D003042:Cocaine / Q000032:analysis*; D005260:Female; D005313:Fetal Death; D005333:Fetus / Q000737:chemistry*; D006801:Humans; D008431:Maternal-Fetal Exchange; D008470:Meconium / Q000737:chemistry*; D011247:Pregnancy; D011248:Pregnancy Complications; D051381:Rats; D017208:Rats, Wistar; D019966:Substance-Related Disorders
D003042:Cocaine