The measured creatinine generation rate in CAPD suggests only 78% of prescribed dialysis is delivered.
The creatinine generation was measured (GCr) in 132 continuous ambulatory peritoneal dialysis (CAPD) patients from the product of total daily peritoneal plus renal creatinine clearance and plasma creatinine (CpCr) plus the product of estimated gut clearance of 0.036 L/kg/day and CpCr. The creatinine generation was also predicted (PGCr) from gender, age, and weight. The mean ratio of MGCr/PGCr was 1.29. Analysis of these data suggests that on average, only 78% of the prescribed dialysis is actually delivered in CAPD patients. Further studies are suggested for the verification of the assumed gut creatinine clearance.
Keen
M
M
Davies Medical Center, San Francisco, California.
Lipps
B
B
Gotch
F
F
D001835:Body Weight; D003404:Creatinine / Q000378:metabolism*; D006801:Humans; D010531:Peritoneal Dialysis, Continuous Ambulatory
D003404:Creatinine