title: Long-term follow-up of 85 patients with obsessive-compulsive disorder.
abstract: In this study, long-term outcome for patients with obsessive-compulsive disorder treated with serotonin reuptake inhibitor medications was examined. The records of 85 patients who had first been evaluated at least 1 year previously (the mean follow-up period was 773 days) were reviewed. Information was collected on age at onset of symptoms, time since first evaluation, and scores on several scales measuring symptom severity, including the Yale-Brown Obsessive Compulsive Scale. Comparison of these baseline data with Yale-Brown scale scores at the most recent follow-up visit showed that 74 (87%) of the patients had responded to treatment. No predictors of improvement were found.
authors.affiliation: Harvard Medical School, Boston, MA.
authors.forename: L M
authors.initials: LM
authors.lastname: Orloff
authors.forename: M A
authors.initials: MA
authors.lastname: Battle
authors.forename: L
authors.initials: L
authors.lastname: Baer
authors.forename: L
authors.initials: L
authors.lastname: Ivanjack
authors.forename: A R
authors.initials: AR
authors.lastname: Pettit
authors.forename: M L
authors.initials: ML
authors.lastname: Buttolph
authors.forename: M A
authors.initials: MA
authors.lastname: Jenike
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors