Colchicine induced remission in amyloid nephrotic syndrome.
An unusual case of reversible reactive amyloidosis (AA) is described. A patient in the course of lobar pneumonia developed acute transient nephrotic syndrome and renal failure. Renal and liver biopsy showed amyloidosis and positive immunohistochemistry stains for amyloid A protein. The nephrotic syndrome resolved completely following 6 months of colchicine treatment and the urine is protein free after 6 years of follow-up.
Oren
R
R
Department of Medicine A, Hadassah University Hospital Ein Kerem, Jerusalem, Israel.
Pizov
G
G
Naparstek
Y
Y
Rubinow
A
A
D000368:Aged; D000667:Ampicillin / Q000627:therapeutic use; D000686:Amyloidosis / Q000188:drug therapy* / Q000209:etiology; D003078:Colchicine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000209:etiology; D011018:Pneumonia, Pneumococcal / Q000150:complications* / Q000188:drug therapy; D012074:Remission Induction
D000667:Ampicillin; D003078:Colchicine