Circadian rhythmicity and cross correlation of plasma gastrin, cortisol and somatostatin levels in ulcerative colitis patients and healthy subjects.
Gastrin, somatostatin and cortisol circadian (24 hours) rhythmicity was confirmed in healthy subjects. Gastrin and cortisol circadian rhythmicity was studied and also established in patients with ulcerative colitis (UC). UC patients were found to have a lower 24-hour amplitude of plasma cortisol and a shorter acrophase of plasma gastrin. Gastrin correlated positively with somatostatin and negatively with cortisol.
Payer
J
J
1st Department of Internal Medicine, Comenius University, Bratislava, Czechoslovakia.
Huorka
M
M
Duris
I
I
Mikulecký
M
M
Kratochvíl'ová
H
H
Ondrejka
P
P
D000328:Adult; D002940:Circadian Rhythm / Q000502:physiology*; D003093:Colitis, Ulcerative / Q000097:blood*; D005260:Female; D005755:Gastrins / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013004:Somatostatin / Q000097:blood*
D005755:Gastrins; D013004:Somatostatin; D006854:Hydrocortisone