title: [The mechanism of apnea during difficult breathing].
abstract: The experiments on anesthetized cats demonstrated that only a combination of hypoxia and inspiratory resistive loading induced respiratory arrest. The findings suggest that both central and peripheral mechanisms of apnea exist due to functional insufficiency of respiratory muscles as a result of synaptic disorder and excitatory contractility disorder in diaphragmatic muscle fibers.
authors.forename: G G
authors.initials: GG
authors.lastname: Isaev
authors.forename: N P
authors.initials: NP
authors.lastname: Aleksandrova
mesh_terms: D000818:Animals; D001049:Apnea / Q000209:etiology* / Q000503:physiopathology; D002245:Carbon Dioxide / Q000502:physiology; D002415:Cats; D004417:Dyspnea / Q000150:complications* / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology; D009584:Nitrogen / Q000494:pharmacology; D010100:Oxygen / Q000494:pharmacology / Q000502:physiology; D010313:Partial Pressure; D012119:Respiration / Q000187:drug effects / Q000502:physiology; D012132:Respiratory Muscles / Q000187:drug effects / Q000503:physiopathology; D013997:Time Factors
chemical_list: D002245:Carbon Dioxide; C041364:nitrox; D009584:Nitrogen; D010100:Oxygen
vernacular_title: Mekhanizm apnoé v usloviiakh zatrudnennogo dykhaniia.