[Changes in the cortical astrocytes of the progeny from the moderate alcoholization of female rats].
It has been shown that in the sensomotor cortex of the offspring of female rats moderately alcoholized during of before pregnancy there are three categories of astrocyte changes: signs of delayed of maturation of some astrocytes, dystrophic and reparative changes. The dystrophic changes include abnormal structures in cytoplasm, edema of mitochondria, damage to the vesicular component of the Golgi apparatus. These changes are more distinct earlier stages of the postnatal ontogenesis. Later the signs of reparative processes are more significant, but the dystrophic astrocyte changes still remain. Changes in cortical astrocytes of the experimental offspring reflect the damage to the neuron-glia-capillary system.
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D000375:Aging / Q000187:drug effects / Q000473:pathology; D000818:Animals; D001253:Astrocytes / Q000187:drug effects* / Q000648:ultrastructure; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000473:pathology*; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000187:drug effects* / Q000648:ultrastructure; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats
D000431:Ethanol
Izmeneniia korkovykh astrotsitov u potomstva pri umerennoĭ alkogolizatsii krys-samok.