Paracetamol (acetaminophen) poisoning.
Paracetamol poisoning caused by intentional overdose remains a common cause of morbidity. In this article the mechanism of toxicity and the clinical effects and treatment of poisoning, including specific antidotal therapy, are reviewed. Areas for further research directed at reducing morbidity and mortality from paracetamol poisoning are considered.
Thomas
S H
SH
Wolfson Department of Clinical Pharmacology, University of Newcastle upon Tyne, U.K.
D000082:Acetaminophen / Q000506:poisoning*; D000818:Animals; D000931:Antidotes / Q000627:therapeutic use; D006801:Humans; D011041:Poisoning / Q000188:drug therapy
D000931:Antidotes; D000082:Acetaminophen