title: Neuropsychological sequelae of methyl bromide: a case study.
abstract: Methyl bromide (MB) is a pesticide used primarily as a fumigating agent for homes, storage vehicles and soil. Chronic exposure to MB is known to cause damage to the central nervous system and other organs. Previously published post-mortem studies have also revealed significant brain abnormalities in patients whose deaths were attributed to MB. Only one study to date has examined the neuropsychological effects of this potential neurotoxin. The present case report documents the events surrounding an incident of acute and subacute MB exposure following home fumigation and the neuropsychological after-effects associated with that exposure. Behavioural and cognitive correlates of CNS dysfunction revealed by the neuropsychological testing included impairments in concentration, information processing, learning and memory. Emotional sequelae appeared to be a secondary problem associated with fears over physical well-being and impaired cognition. The cognitive symptomatology did not abate after completion of litigation and award of compensation.
authors.affiliation: NeuroMedical Center, Baton Rouge, LA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Reidy
authors.forename: J F
authors.initials: JF
authors.lastname: Bolter
authors.forename: J E
authors.initials: JE
authors.lastname: Cone
mesh_terms: D001925:Brain Damage, Chronic / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D005104:Expert Testimony / Q000331:legislation & jurisprudence; D005260:Female; D005651:Fumigation / Q000331:legislation & jurisprudence; D006801:Humans; D006842:Hydrocarbons, Brominated / Q000506:poisoning*; D016365:Liability, Legal; D008606:Mental Processes / Q000187:drug effects*; D008875:Middle Aged; D009483:Neuropsychological Tests; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000523:psychology
chemical_list: D006842:Hydrocarbons, Brominated; C005218:methyl bromide