title: [A case of herpes simplex encephalitis presenting complete destruction of the medial portions in the bilateral temporal lobes].
abstract: A 57-year old man, who had suffered from herpes simplex encephalitis and had been cured without antiviral agents, was admitted to our hospital three years after the encephalitis. He had a complete loss of memory for events subsequent to the encephalitis and a retrograde amnesia for the several years leading up the encephalitis. MRI revealed the abnormalities located in the limbic system, especially the medial portions in the bilateral temporal lobes of the cerebrum were completely destroyed. We consider that this case suggests the specific affinity of herpes simplex virus especially for the medial portions in the temporal lobes of the cerebrum.
authors.affiliation: Department of Neurology, Senboku National Hospital, Osaka, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Shimada
authors.forename: N
authors.initials: N
authors.lastname: Ueda
authors.forename: M
authors.initials: M
authors.lastname: Ikeda
authors.forename: J
authors.initials: J
authors.lastname: Takaishi
authors.forename: H
authors.initials: H
authors.lastname: Tanabe
mesh_terms: D000648:Amnesia, Retrograde / Q000209:etiology*; D004660:Encephalitis / Q000473:pathology* / Q000523:psychology; D005625:Frontal Lobe / Q000473:pathology*; D006561:Herpes Simplex / Q000473:pathology* / Q000523:psychology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous