Sexual dimorphism of binding sites of testosterone and dihydrotestosterone in rabbit model.
1. Binding sites for testosterone (TR) and dihydrotestosterone (DHTR) were separately detected in various organs of the rabbit. 2. Possibilities obtained were suggested as follows. 3. Sexual dimorphism of TR or DHTR level was present among organs. 4. The responsiveness of TR or DHTR levels to estradiol-17 beta with testosterone, but not estradiol-17 beta alone is different among organs, with sexual minor dimorphism.
Tamaya
T
T
Department of Obstetrics and Gynecology, Gifu University School of Medicine, Japan.
Wada
K
K
Nakagawa
M
M
Misao
R
R
Itoh
T
T
Imai
A
A
Mori
H
H
D000728:Androgens / Q000494:pharmacology; D000818:Animals; D001011:Aorta / Q000378:metabolism; D001665:Binding Sites; D013196:Dihydrotestosterone / Q000378:metabolism*; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D008099:Liver / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism; D011817:Rabbits; D012727:Sex Characteristics; D013739:Testosterone / Q000378:metabolism*; D014316:Tritium; D014599:Uterus / Q000378:metabolism
D000728:Androgens; D004967:Estrogens; D013196:Dihydrotestosterone; D014316:Tritium; D013739:Testosterone