Chronic hypothermia and water intoxication associated with a neurodegenerative disease.
We describe a 71 year old man with a neurodegenerative condition who developed chronic inappropriate antidiuretic hormone secretion and hypothermia resulting in recurrent episodes of impaired consciousness. This combination of abnormalities is attributable to hypothalamic disease and has not to our knowledge been previously reported with clearly documented antidiuretic hormone excess.
Corbett
E L
EL
Department of Medicine, Whittington Hospital, London, UK.
Sisodiya
S
S
Sarkar
D
D
D000368:Aged; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000097:blood / Q000150:complications*; D006801:Humans; D007010:Hyponatremia / Q000097:blood / Q000150:complications*; D007035:Hypothermia / Q000097:blood / Q000150:complications*; D008297:Male; D014667:Vasopressins / Q000097:blood; D014869:Water Intoxication / Q000097:blood / Q000150:complications*
D014667:Vasopressins