Synthesis markers in illegally manufactured 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine.
In this paper the isolation and identification of 12 compounds as impurities in illicit 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA) is reported. Isolation of these substances is performed by preparative TLC, while identification is performed by using mass spectrometry and 1H-NMR spectroscopy. A simple and rapid method for detection of these impurities in seized MDA and MDMA samples is described. The identification of the impurities can provide numerous points on which to base comparative analysis of different exhibits.
Bohn
M
M
Institut für Rechtsmedizin, Westfälische Wilhelms-Universität, Münster, Germany.
Bohn
G
G
Blaschke
G
G
D015104:3,4-Methylenedioxyamphetamine / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D015198:Designer Drugs / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D004335:Drug and Narcotic Control / Q000331:legislation & jurisprudence*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D013287:Illicit Drugs / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D018817:N-Methyl-3,4-methylenedioxyamphetamine
D015198:Designer Drugs; D013287:Illicit Drugs; D015104:3,4-Methylenedioxyamphetamine; D018817:N-Methyl-3,4-methylenedioxyamphetamine