title: Sexual precocity: sex incidence and aetiology.
abstract: The aetiology of 197 girls and 16 boys presenting with sexual precocity was reviewed. Ninety one girls and four boys had central precocious puberty (M:F 23:1); a cause was identified in all the boys but in only six girls. All boys with precocious puberty need detailed investigation; in girls investigation should be based on clinical findings, particularly the consonance of puberty.
authors.affiliation: Endocrine Unit, Cobbold Laboratories, Middlesex Hospital, London.
authors.forename: N A
authors.initials: NA
authors.lastname: Bridges
authors.forename: J A
authors.initials: JA
authors.lastname: Christopher
authors.forename: P C
authors.initials: PC
authors.lastname: Hindmarsh
authors.forename: C G
authors.initials: CG
authors.lastname: Brook
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000150:complications; D000728:Androgens / Q000096:biosynthesis; D001927:Brain Diseases / Q000150:complications; D001940:Breast / Q000254:growth & development; D002648:Child; D005260:Female; D006062:Gonadotropins / Q000502:physiology; D006066:Gonads / Q000503:physiopathology; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D008297:Male; D011629:Puberty, Precocious / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D012737:Sex Factors
chemical_list: D000728:Androgens; D006062:Gonadotropins