title: Somatostatin inhibits cell proliferation and corticosterone secretion in the early stage of adrenal regeneration.
abstract: Somatostatin was given to male Wistar rats subjected to adrenal enucleation combined with monoadrenalectomy. It was found that somatostatin (25 micrograms/kg) inhibited both cell proliferation and corticosterone output on the fourth and on the eighth days of adrenal regeneration.
authors.affiliation: Clinic of Endocrinology, Institute of Endocrinology, Lódź, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Zieleniewski
authors.forename: J
authors.initials: J
authors.lastname: Zieleniewski
mesh_terms: D000305:Adrenal Cortex Hormones / Q000097:blood / Q000378:metabolism*; D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D008297:Male; D008940:Mitotic Index; D011863:Radioimmunoassay; D051381:Rats; D017208:Rats, Wistar; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*; D013004:Somatostatin / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones; D013004:Somatostatin