[The effect of glutamate on the dopamine content and metabolism in the nigrostriatal system of rats differing by their learning capacities].
Microinjections of glutamate increased striatal dopamine efflux in naive rats, whereas in rats capable of learning the same microinjections increased the dopamine level in the striatum. The microinjections induced no changes in learning ability of rats.
Karpova
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Iakimovskiĭ
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D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D003342:Corpus Striatum / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D004298:Dopamine / Q000032:analysis / Q000378:metabolism*; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D005971:Glutamates / Q000008:administration & dosage / Q000494:pharmacology*; D018698:Glutamic Acid; D007858:Learning / Q000187:drug effects* / Q000502:physiology; D008297:Male; D008845:Microinjections; D051381:Rats; D017207:Rats, Sprague-Dawley; D013378:Substantia Nigra / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000032:analysis / Q000187:drug effects / Q000378:metabolism
D005971:Glutamates; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D004298:Dopamine
Vliianie glutamata na soderzhanie i metabolizm dofamina v nigrostriatnoĭ sisteme krys, razlichaiushchikhsia po sposobnosti k obucheniiu.