Ethylene vinylacetate copolymer particles dissolved in polyvinyl alcohol (2,000-mer) solution as an embolic material for vascular anomalies. A preliminary study.
We have prepared a new material for embolisation: ethylene vinylacetate copolymer dissolved in polyvinyl alcohol. When in contact with blood, polyvinyl alcohol rapidly becomes a soft gel, which is accompanied by wedging of the ethylene vinylacetate copolymer. We analysed the histopathology of intra-arterial microemboli in rats, after intracarotid injection of this material. We confirmed that it was applicable to embolisation for neurosurgical treatment.
Kinoshita
A
A
Department of Neurosurgery, Osaka University Medical School, Japan.
Yamada
K
K
Ito
M
M
Yamazaki
M
M
Taneda
M
M
Hayakawa
T
T
D000818:Animals; D001165:Arteriovenous Malformations / Q000628:therapy; D002343:Carotid Artery, Internal / Q000473:pathology; D002648:Child; D004621:Embolization, Therapeutic; D006801:Humans; D007269:Injections, Intra-Arterial; D002538:Intracranial Arteriovenous Malformations / Q000628:therapy; D008297:Male; D011142:Polyvinyl Alcohol / Q000008:administration & dosage; D011145:Polyvinyls / Q000008:administration & dosage; D051381:Rats; D017208:Rats, Wistar
D011145:Polyvinyls; C016438:ethylenevinylacetate copolymer; D011142:Polyvinyl Alcohol