title: Influence of phaseolotoxin on the alkaloid accumulation in Datura innoxia Mill.
abstract: In crude protein extracts of aseptically grown plantlets of Datura innoxia ornithine carbamoyltransferase was detected. The ornithine carbamoyltransferase of plant extracts was inhibited by phaseolotoxin. The level of this inhibition was dependent on the concentration of the toxin applied. Subsequent accumulation of ornithine in plant vegetative parts was observed. Phaseolotoxin influenced both the vitability and alkaloid accumulation of treated plants.
authors.affiliation: Institute of Pharmacognosy, Semmelweis Medical University, Budapest, Hungary.
authors.forename: N
authors.initials: N
authors.lastname: Missaleva
authors.forename: G
authors.initials: G
authors.lastname: Petri
authors.forename: G
authors.initials: G
authors.lastname: Reuter
authors.forename: E
authors.initials: E
authors.lastname: Szöke
authors.forename: U
authors.initials: U
authors.lastname: Markish
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification / Q000378:metabolism*; D005098:Exotoxins / Q000494:pharmacology*; D009952:Ornithine / Q000031:analogs & derivatives; D009954:Ornithine Carbamoyltransferase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D010944:Plants / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*
chemical_list: D000470:Alkaloids; D005098:Exotoxins; C021234:phaseolotoxin; D009952:Ornithine; D009954:Ornithine Carbamoyltransferase