The detection of IgG against a specific mycobacterial antigen (A60) in the diagnosis of tuberculous pericarditis.
Diagnosis of tuberculous pericarditis (TP) is often difficult with standard methods, while prompt recognition of this disease may affect its prognosis. We report a case of tuberculous pericarditis, in which the presumptive diagnosis was obtained by detection of specific immunoglobulin G (IgG) against A60 antigen, the main thermostable component of purified protein derivative (PPD). Serological diagnosis may be a useful approach in the screening of the aetiology of pericarditis.
Molino
A
A
Clinica delle Malattie dell'Apparato Respiratorio, Facoltà di Medicina e Chirurgia, Università di Napoli Federico II, Italy.
Carratù
P
P
Alifano
M
M
Sofia
M
M
D000368:Aged; D000942:Antigens, Bacterial / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D010495:Pericarditis, Tuberculous / Q000175:diagnosis* / Q000276:immunology
D000942:Antigens, Bacterial; D007074:Immunoglobulin G; C055539:mycobacterial A60 antigen