Ceftazidime-related nonconvulsive status epilepticus.
The third-generation cephalosporin, ceftazidime, is widely used for the treatment of serious gram-negative infections. As is true of cephalosporins in general, reported adverse effects have been few. We report a case of ceftazidime-induced status epilepticus in a patient with Pseudomonas aeruginosa meningitis and compare the clinical manifestations of this case with those of two previously described cases of ceftazidime-related encephalopathy. This diagnosis should be entertained and an electroencephalogram should be obtained in all patients with myoclonus and/or altered mental status while they are receiving ceftazidime therapy.
Klion
A D
AD
Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City.
Kallsen
J
J
Cowl
C T
CT
Nauseef
W M
WM
D000368:Aged; D002442:Ceftazidime / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy; D011552:Pseudomonas Infections / Q000188:drug therapy; D013226:Status Epilepticus / Q000139:chemically induced*
D002442:Ceftazidime