[Cardiac manifestations of phospholipid antibody syndrome. Study of 2 cases].
Cardiac manifestations of phospholipid antibody syndrome may include mitral and/or aortic valve disease, pseudo-infectious endocarditis, thrombi of the right atrium, myocardial infection, pulmonary artery hypertension and cardiomyopathy with global or segmental left ventricular dysfunction. The authors report two patients showing evidence simultaneously of a circulating anticoagulant, dissociated syphilis serology and cardiolipin antibodies at a very high level. They had the majority of cardiac complications described in phospholipid antibody syndrome. Both also had renal involvement and one of them had recurrent venous thromboses and a cerebrovascular accident. Prolonged corticosteroid treatment, combined with anticoagulants in one patient, was accompanied by stability of lesions with follow-up of five years and ten months respectively.
Rojas
M
M
Service de Néphrologie et de Réanimation polyvalente, Centre hospitalier, Montreuil.
Gryman
R
R
Bournazel
V
V
Fourchard
V
V
Kleinknecht
D
D
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000628:therapy; D006331:Heart Diseases / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged
Les manifestations cardiaques du syndrome des anticorps antiphospholipides. Etude de deux observations.