Screening for retinopathy of prematurity: are a lid speculum and scleral indentation necessary?
We wanted to investigate the value of using a lid speculum and scleral indentation in performing binocular indirect ophthalmoscopy (BIO) in neonates at risk of retinopathy of prematurity (ROP). We performed a prospective masked comparison of BIO examinations using either a lid speculum and scleral indentation (SI) or no scleral indentation (NSI), in our neonatal intensive care unit. We did 57 consecutive BIO examinations of infants weighing less than 1500 g and/or having a gestational age of less than 32 weeks. With NSI, zone I ROP was reliably seen in 53 of 57 examinations; the superior, nasal, and temporal aspects of zone II were seen in 45 of 57 examinations; inferior zone II, in 22 of 57 examinations; and zone III in 1 of 57 examinations. SI facilitated complete peripheral fundus examination in all cases but had to be abandoned in two infants due to acute changes in oxygen saturation levels. Five infants developed threshold disease, and in two of them details of the active ROP ridge were missed with NSI. The gentle use of an eyelid speculum and globe rotation allows rapid and relatively atraumatic assessment of the peripheral fundus, even in babies who are being ventilated. Although threshold ROP may be diagnosed by observation of posterior retinal vessel dilation and tortuosity ("plus" disease), accurate grading of ROP is likely to require SI. In the absence of clearly developed "plus" disease, borderline or prethreshold disease may occasionally be missed using BIO with NSI. SI is necessary to examine the inferior midperipheral retinal vasculature (zone II) and the far peripheral temporal retina (zone III) and is associated with few complications.(ABSTRACT TRUNCATED AT 250 WORDS)
Dhillon
B
B
Princess Alexandra Eye Pavilion, Edinburgh, Scotland.
Wright
E
E
Fleck
B W
BW
D005654:Fundus Oculi; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D009885:Ophthalmology / Q000295:instrumentation*; D009887:Ophthalmoscopy / Q000379:methods*; D011446:Prospective Studies; D012160:Retina / Q000473:pathology; D012178:Retinopathy of Prematurity / Q000175:diagnosis*; D012590:Sclera / Q000502:physiology*