title: [Evaluation of fetal intrauterine growth retardation by measurement of umbilical arterial blood flow velocity combined with ultrasonography].
abstract: A simple continuous-wave Doppler ultrasound analyzer was used to obtain umbilical artery waveforms and to calculate the peak-systolic/diastolic ratio (S/D). 140 pregnant women who were considered to be their fetal intrauterine growth retardation (IUGR) by B-type ultrasonography were measured. A total of 220 examinations were performed. The 140 pregnant women were divided into two groups. 54 women whose the neonates ceatile birth weight < or = 10th% were in SGA group. The other 86 pregnancies were be in AGA group. S/D ratio in SGA group is significantly higher than in AGA group. If S/D ratio > or = 90th% of normal pregnancies is abnormal, the sensitivity was 82%, the specificity was 86%, the predictive value of a positive test was 81% and the predictive value of a negative test was 87% when IUGR was diagnosed by combined umbilical S/D ratio with ultrasonography estimate of fetal weight. Compared the abnormal S/D ratio with the normal S/D ratio in SGA group, there was a significantly higher incidence of preterm birth, dystocia, fetal distress and perinatal death (P < 0.01). Especially, when S/D > or = 4 in full term cases the incidence of Apgar score < 7 at 1 min and perinatal death was increased to 60% and 30%. Other three fetuses with absent end diastolic velocity (AEDV) were all death. These data suggest that combined umbilical artery velocity S/D ratio with B-type ultrasonography can increase diagnostic reliability of IUGR, and it is important in foreseen prognosis of SGA fetus.
authors.affiliation: Obstet and Gynecol Hospital, Shanghai Medical University.
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Zhang
mesh_terms: D001783:Blood Flow Velocity; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging*; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000503:physiopathology*