title: Sequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes.
abstract: Genes for MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamases have been cloned and sequenced. The gene for MGH-1 has the sequence of blaTEM-10, YOU-2 has that of blaTEM-12, and YOU-1 has that of blaTEM-26. All have evolved from blaTEM-1b but have the strong dual promoter sequence of blaTEM-2.
authors.affiliation: Department of Veterans Affairs Medical Center, Cleveland, Ohio.
authors.forename: L B
authors.initials: LB
authors.lastname: Rice
authors.forename: S H
authors.initials: SH
authors.lastname: Marshall
authors.forename: L L
authors.initials: LL
authors.lastname: Carias
authors.forename: L
authors.initials: L
authors.lastname: Sutton
authors.forename: G A
authors.initials: GA
authors.lastname: Jacoby
mesh_terms: D000595:Amino Acid Sequence; D003001:Cloning, Molecular; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D001618:beta-Lactamases; C034413:beta-lactamase TEM-1; C056342:beta-lactamase TEM-2