Mechanism of conversion of verdomyoglobin to ferric complex of biliverdin.
The reaction of conversion of verdoheme to Fe(III)biliverdin was studied with different hemeproteins (Mb, HRP, and BrCN modified Mb). It was shown that the heme iron of Mb is not involved in this reaction. It was also shown that the extra oxygen atom in biliverdin does not come from H2O2 or water molecules. Based on these results a mechanism for this reaction is proposed.
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Department of Biochemistry, University of Cambridge, England, U.K.
D001654:Bile Pigments / Q000737:chemistry; D001664:Biliverdine / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D006420:Hemeproteins / Q000737:chemistry; D009211:Myoglobin / Q000737:chemistry*; D010940:Plant Proteins; D013053:Spectrophotometry
D001654:Bile Pigments; D005290:Ferric Compounds; D006420:Hemeproteins; D009211:Myoglobin; C023351:P-670 verdohemoprotein, plant; D010940:Plant Proteins; C003759:verdohemochrome; D001664:Biliverdine