title: Two CA/GT repeat polymorphisms in intron 27 of the human neurofibromatosis (NF1) gene.
abstract: We describe two polymorphic microsatellites in intron 27 of the neurofibromatosis type 1 (NF1) gene. The microsatellites consist of TG/AC and AC/TG dinucleotide repeats detecting five and seven alleles and with heterozygosities of 0.46 and 0.72, respectively. These microsatellites are useful tools both for direct and indirect genetic analysis of NF1.
authors.affiliation: Molecular Genetics Department, I.R.O., Hospital Duran i Reynals, Catalunya, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Lázaro
authors.forename: A
authors.initials: A
authors.lastname: Gaona
authors.forename: X
authors.initials: X
authors.lastname: Estivill
mesh_terms: D000483:Alleles; D001483:Base Sequence; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D004276:DNA, Satellite; D005787:Gene Frequency; D016514:Genes, Neurofibromatosis 1; D006801:Humans; D007438:Introns; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D004276:DNA, Satellite