title: Successful management of a pregnancy with maternal phenylketonuria: report of a case.
abstract: Maternal phenylketonuria (PKU) is associated with significant complications such as mental retardation, microcephaly and congenital heart defects in nonphenylketonuric offspring. Dietary control with a low phenylalanine diet during the gestation period is effective in improving perinatal outcome in these cases. We present the case of a 27-year-old woman with classical features of PKU who had previously given birth to three babies, all of whom died of congenital heart disease. A low phenylalanine diet was started one month prior to the pregnancy and satisfactory fetal outcome was achieved.
authors.affiliation: Department of Obstetrics & Gynecology, National Cheng-Kung University Medical Center, Tainan, Taiwan, R.O.C.
authors.forename: R T
authors.initials: RT
authors.lastname: Huang
authors.forename: S J
authors.initials: SJ
authors.lastname: Lin
authors.forename: P L
authors.initials: PL
authors.lastname: Kuo
authors.forename: C J
authors.initials: CJ
authors.lastname: Peng
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010661:Phenylketonurias / Q000178:diet therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000178:diet therapy*; D011295:Prenatal Care