[Segmental arterial compliance of the radial artery: physiological role of age, hypertension and type I insulin-dependent-diabetes].
OBJECTIVE
To study the structural modifications of a muscular and medium-size radial artery as regards age, in normal subjects (NT) and HT and DTI.


METHODS
Transverse study with 39 NT aged 48 +/- 16 years, were compared to 22 HT, aged 50 +/- 11 years, and to 22 DT aged 37 +/- 12 years. An echo-tracking system (NIUS 01, Asulabs, Neuchatel, Switzerland) were used to measure the systolic (Ds) and diastolic diameter (Dd) and derive three indices of compliance and storage capacity: systolo-diastolic variation of cross sectional area VSCA = tau [(Ds2/4)-(Dd2/4)] mm2, operative arterial compliance CA = tau Dd (Ds-Dd)/2 (PAS-PAD) in mm2/mmHg.


RESULTS
1. In NT, Ds and Dd increased significantly with age (p < 0.01), likewise the VSCA, and CA (p < 0.002). 2. In HT and DTI, when age was taken into account, the Ds and Dd were significantly greater than in control but VCSA and CA were higher in HT and lower in DT.


CONCLUSIONS
Similar to ageing changes in NT, HT lead to increase in medium-size radial artery the diameter and storage capacity, while to decrease in DT. This suggests that opposite cardiovascular load induce opposite modifications in arterial wall structure leading to reduce the wall stress.
Siché
J P
JP
Service de médecine interne et cardiologie, CHU, Grenoble.
de Gaudemaris
R
R
Tremel
F
F
Riachi
M
M
Halimi
S
S
Mallion
J M
JM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D003187:Compliance; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D017534:Radial Artery / Q000502:physiology*
Compliance artérielle segmentaire de l'artère radiale: rôle physiologique de l'âge, de l'hypertension artérielle et du diabète insulino-dépendant de type I.