beta-Carotene reduces paw swelling in the rat adjuvant arthritis model, while increasing IL-1 production in peritoneal macrophages.
Bachmann
H
H
Vitamin Research, F. Hoffmann-La Roche, Ltd, Basel, Switzerland.
Nemzek
R
R
Coffey
J W
JW
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001169:Arthritis, Experimental / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology; D002338:Carotenoids / Q000627:therapeutic use*; D002478:Cells, Cultured; D004487:Edema / Q000276:immunology / Q000517:prevention & control*; D007371:Interferon-gamma / Q000494:pharmacology; D007375:Interleukin-1 / Q000096:biosynthesis*; D008070:Lipopolysaccharides / Q000633:toxicity; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000276:immunology / Q000378:metabolism*; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D011994:Recombinant Proteins; D013997:Time Factors; D019207:beta Carotene
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007375:Interleukin-1; D008070:Lipopolysaccharides; D011994:Recombinant Proteins; D019207:beta Carotene; D002338:Carotenoids; D007371:Interferon-gamma