title: [The technology for manufacturing antiparasitic preparations. 1. The development of a technology for producing the anthelmintic triklazan in finely dispersed form and the evaluation of its antinematodal, anticestodal and antitrematodal activities].
abstract: The authors describe the technology of preparing a new anthelmintic agent triclazan, N-(3,4-dichlorophenyl)-2-[(benzo-2,1,3-thiadiazole-4-sulfonyl)amino]-5- chlorobenzamide, finely dispersed (the particles size 4-8 mu). Triclazan is highly effective not only in hymenolepiasis and trichocephaliasis, as was shown previously, but in fascioliasis, monieziasis and intestinal nematodiasis of sheep as well.
authors.forename: F S
authors.initials: FS
authors.lastname: Mikhaĭlitsyn
authors.forename: Iu F
authors.initials: IuF
authors.lastname: Petrov
authors.forename: A A
authors.initials: AA
authors.lastname: Smirnov
authors.forename: S K
authors.initials: SK
authors.lastname: Drusviatskaia
authors.forename: A G
authors.initials: AG
authors.lastname: Aleksandrov
authors.forename: N A
authors.initials: NA
authors.lastname: Uvarova
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Kazarin
authors.forename: V N
authors.initials: VN
authors.lastname: Lozlov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Bol'shakova
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage* / Q000138:chemical synthesis* / Q000737:chemistry; D002590:Cestode Infections / Q000188:drug therapy / Q000662:veterinary; D004353:Drug Evaluation, Preclinical; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary; D010316:Particle Size; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy; D013830:Thiadiazoles / Q000008:administration & dosage* / Q000138:chemical synthesis* / Q000737:chemistry; D014201:Trematode Infections / Q000188:drug therapy / Q000662:veterinary
chemical_list: D000871:Anthelmintics; D013830:Thiadiazoles; C086170:triclazan
vernacular_title: Tekhnologiia proizvodstva protivoparazitarnykh preparatov. Soobshchenie 1. Razrabotka tekhnologii polucheniia antigel'mintika triklazana v melkodispersnoĭ forme i otsenka ego protivonematodnoĭ, protivotsestodnoĭ i protivotrematodnoĭ aktivnosti.