title: [Clinical utility of thallium-201 chloride in the diagnosis of parathyroid glands in patients with hyperparathyroidism].
abstract: Clinical utility for detection of hyperfunctioning parathyroid glands in patients with primary and secondary hyperparathyroidism (PHPT, SHPT) using 201TlCl and 99mTcO4-images was estimated in 50 patients including 18 PHPT and 32 SHPT (male; n = 31, female; n = 19, 51.5 +/- 11.1 yr). Detection of 94 hyperfunctioning parathyroid glands in 34 cases were achieved correctly by 201TlCl and 99mTcO4- images in agreement with surgical findings. Detectability of hyperfunctioning parathyroid glands was 100% in more than 1.0 g, 62.0% in more than 0.5 g and 41.5% in less than 0.5 g respectively. Ectopic parathyroid glands in two cases and a metastasis to pretracheal lymph node in one case were clearly demonstrated. Our results show that parathyroid scintigraphy using 201TlCl and 99mTcO4- as well as 131I or 123I is useful and safe method for preoperative detection of hyperfunctioning parathyroid glands.
authors.affiliation: Department of Nuclear Medicine, Hyogo College of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fukuchi
authors.forename: M
authors.initials: M
authors.lastname: Suehiro
authors.forename: K
authors.initials: K
authors.lastname: Kusakabe
authors.forename: M
authors.initials: M
authors.lastname: Maki
authors.forename: N
authors.initials: N
authors.lastname: Ohtsuka
authors.forename: M
authors.initials: M
authors.lastname: Katagiri
authors.forename: K
authors.initials: K
authors.lastname: Torizuka
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging*; D006962:Hyperparathyroidism, Secondary / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000000981:diagnostic imaging*; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013793:Thallium; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes; C027549:thallium chloride; D013793:Thallium