Development of a new laser-Doppler microvelocimetering and its application in patients with coronary artery stenosis.
A new Laser-Doppler microvelocimetering (LDMV) was developed to study blood flow in individual vessels in patients with coronary artery stenosis. The LDMV measures steady blood flow velocity, diameter of vessels and pulsation flow. In addition, the effects of China's traditional herbs--Salvia Mitiorrhyza and other drugs--on the blood flow in the patients were investigated. LDMV constitutes a new quantitative procedure and is a promising tool for rapid monitoring of tissue perfusion in cardiovascular disease and estimating the action of drugs on microcirculation.
Jiang
S
S
Nanjing Jin Lin Hospital, P.R., China.
Yu
G
G
Xu
S Z
SZ
D001783:Blood Flow Velocity / Q000187:drug effects; D003251:Constriction, Pathologic / Q000503:physiopathology; D003326:Coronary Circulation / Q000187:drug effects; D003327:Coronary Disease / Q000503:physiopathology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods*; D008297:Male; D008833:Microcirculation / Q000187:drug effects / Q000503:physiopathology; D008875:Middle Aged; D010936:Plant Extracts; D010974:Platelet Aggregation / Q000187:drug effects; D027561:Salvia miltiorrhiza
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts