Vitamin E treatment of tardive dyskinesia.
OBJECTIVE
The authors studied the effects of vitamin E treatment of tardive dyskinesia; earlier studies have produced contradictory results.


METHODS
Twenty-eight patients with tardive dyskinesia were treated in a double-blind, parallel-group comparison study of 8-12 weeks of treatment with vitamin E (1600 IU/day) or matching placebo capsules.


RESULTS
The Abnormal Involuntary Movement Scale scores of the patients treated with vitamin E improved significantly compared to the scores of the patients given placebo.


CONCLUSIONS
These results support earlier findings of the efficacy of vitamin E in treating tardive dyskinesia.
Adler
L A
LA
Psychiatry Service, New York Department of Veterans Affairs Medical Center, NY 10010.
Peselow
E
E
Rotrosen
J
J
Duncan
E
E
Lee
M
M
Rosenthal
M
M
Angrist
B
B
D000553:Ambulatory Care; D014150:Antipsychotic Agents / Q000009:adverse effects; D004311:Double-Blind Method; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy* / Q000209:etiology; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D012559:Schizophrenia / Q000188:drug therapy; D014810:Vitamin E / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D010919:Placebos; D014810:Vitamin E