title: Turner's syndrome associated with sigmoid polyp and colon cancer: report of a case.
abstract: A 49-year-old woman with 45,XO karyotype Turner's syndrome and a recent onset of loose-to-watery stool passage was found to have a sigmoid polyp and adenocarcinoma in the ascending colon. Turner's syndrome is a result of a variety of abnormalities of the X chromosome. There are reports that the risk of malignancy, both gonadal and nongonadal in origin, is increased in patients with such chromosomal defects. Although, diet and heredity play important roles in the etiology of colorectal cancer, the relationship between cancer and certain congenital defects should be taken into account.
authors.affiliation: Department of Internal Medicine, Father Fox Memorial Hospital, Tainan, Taiwan, R.O.C.
authors.forename: H M
authors.initials: HM
authors.lastname: Cheng
authors.forename: M C
authors.initials: MC
authors.lastname: Tsai
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology; D003111:Colonic Polyps / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D012811:Sigmoid Neoplasms / Q000150:complications* / Q000473:pathology; D014424:Turner Syndrome / Q000150:complications*