title: Drug-related lupus in a patient with rheumatoid arthritis under sulfasalazine treatment.
abstract: The induction of lupus-like syndromes with the appearance of single-stranded DNA antibodies is a well-known complication of drug therapy. In this report we present a patient with an erosive seropositive rheumatoid arthritis developing the clinical and serological features of systemic lupus erythematosus including the occurrence of double-stranded DNA antibodies under sulfasalazine treatment.
authors.affiliation: Abt. Immunologie, Medizinische Hochschule Hannover, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Wildhagen
authors.forename: K
authors.initials: K
authors.lastname: Hartung
authors.forename: M
authors.initials: M
authors.lastname: Hammer
authors.forename: W
authors.initials: W
authors.lastname: Mau
authors.forename: R E
authors.initials: RE
authors.lastname: Schmidt
authors.forename: H
authors.initials: H
authors.lastname: Deicher
authors.forename: H
authors.initials: H
authors.lastname: Zeidler
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004247:DNA / Q000276:immunology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000276:immunology; D012460:Sulfasalazine / Q000627:therapeutic use*
chemical_list: D000974:Antibodies, Antinuclear; D012460:Sulfasalazine; D004247:DNA