title: [Fulminant pneumococcal septicemia in a splenectomized child despite vaccination and chemoprophylaxis: necessity for education of the entourage].
abstract: A splenectomized three-year-old developed fulminant pneumococcal septicemia despite immunization and chemoprophylaxis. The course was rapidly fatal. Fulminant pneumococcal septicemia mainly affects splenectomized individuals and is associated with very substantial mortality. Immunization prior to splenectomy and daily prophylactic oral penicillin have partial preventive efficacy. Other useful measures include carrying a health status card and inpatient antimicrobial therapy in the event of fever. The need for these precautions should be repeatedly discussed with the child's parents and physician.
authors.affiliation: Service de Réanimation Pédiatrique et Néonatologie, CHRU, Brest.
authors.forename: J
authors.initials: J
authors.lastname: Sizun
authors.forename: D
authors.initials: D
authors.lastname: Prigent
authors.forename: D
authors.initials: D
authors.lastname: Tande
authors.forename: J D
authors.initials: JD
authors.lastname: Giroux
authors.forename: S
authors.initials: S
authors.lastname: Rubio
authors.forename: D
authors.initials: D
authors.lastname: Alix
authors.forename: L
authors.initials: L
authors.lastname: de Parscau
mesh_terms: D016470:Bacteremia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D001428:Bacterial Vaccines / Q000008:administration & dosage; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D010290:Parents / Q000193:education; D010404:Penicillin V / Q000627:therapeutic use; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D022242:Pneumococcal Vaccines; D011322:Primary Prevention / Q000379:methods; D013156:Splenectomy / Q000009:adverse effects*
chemical_list: D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines; D010404:Penicillin V
vernacular_title: Septicémie fulminante à pneumocoque chez un enfant splénectomisé, malgré vaccination et chimioprophylaxie: nécessité de l'éducation de l'entourage.