title: Well-developed infant with hypoxic-ischemic encephalopathy associated with EEG burst suppression and subcortical leukohypodensity on CT scan.
abstract: In the prediction of neurological sequelae after hypoxic-ischemic encephalopathy (HIE) in the newborn, the electroencephalogram (EEG) burst suppression pattern (BS) and subcortical leukomalacia can mean grave neurodevelopmental problems will develop. This study presents an infant with HIE associated with BS and subcortical leukohypodensity (SLH) on computed tomography scan. At first her neurodevelopmental outcome was considered poor, but unexpectedly she showed good development in 32 months follow-up. The findings of BS and SLH do not always result in a poor neurodevelopmental outcome, if the subsequent clinical state and EEG return to normal at an early stage.
authors.affiliation: Department of Pediatrics, Aoto Hospital, Tokyo Jikei University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Sugama
authors.forename: M
authors.initials: M
authors.lastname: Okazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Nakanishi
authors.forename: F
authors.initials: F
authors.lastname: Ito
authors.forename: Y
authors.initials: Y
authors.lastname: Eto
authors.forename: K
authors.initials: K
authors.lastname: Maekawa
mesh_terms: D002545:Brain Ischemia / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D007231:Infant, Newborn; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D011379:Prognosis; D014057:Tomography, X-Ray Computed