Large-scale production of infectious bovine rhinotracheitis virus in cell culture on microcarriers.
Large amounts of infectious bovine rhinotracheitis (IBR) virus was produced in Madin-Darby bovine kidney (MDBK) cells in suspension culture on the microcarriers Gelaspher M. Virus yields (TCID50 per ml) were approximately 10-times higher as compared to classical stationary cell culture.
Lesko
J
J
Institute of Virology, Slovak Academy of Sciences, Bratislava.
Veber
P
P
Hrda
M
M
Feketeová
M
M
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D046508:Culture Techniques / Q000379:methods; D007242:Herpesvirus 1, Bovine / Q000254:growth & development*; D014776:Virus Cultivation; D014779:Virus Replication