title: Peritumorous lymph-vascular invasion, grade of histologic differentiation, and myometrial infiltration as prognostic factors of endometrial carcinoma.
abstract: The authors evaluated 50 patients with endometrial carcinoma studying the prognostic parameters: histologic grade, myometrial invasion and lymph-vascular space invasion. The patients were divided into two groups: A--a good prognosis group (33 cases)--with no recurrences and/or metastasis occurring for five years; and B--a bad prognosis group (17 cases)--with recurrence and/or metastasis or death within five years. We concluded that lymph-vascular space invasion was more frequent in group B, and was a reliable parameter for bad prognosis. The lymph-vascular space invasion was always accompanied by myometrial invasion and patients whose myometrium had not been involved did not have lymph-vascular space invasion. In both groups, in well-differentiated tumors, there was no lymph-vascular space involvement. The well-differentiated tumors were statistically more frequent in the good prognosis group. Myometrial invasion was not statistically significant as a prognostic parameter.
authors.affiliation: Escola Paulista de Medicina, São Paulo, Brasil.
authors.forename: N M
authors.initials: NM
authors.lastname: De Góis
authors.forename: N V
authors.initials: NV
authors.lastname: Martins
authors.forename: F S
authors.initials: FS
authors.lastname: Abrão
authors.forename: G R
authors.initials: GR
authors.lastname: De Lima
authors.forename: A C
authors.initials: AC
authors.lastname: Alves
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001808:Blood Vessels / Q000473:pathology; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis