title: [Pulmonary metastases from a hormone-induced clear cell adenocarcinoma of the vagina].
abstract: The authors report the case of a patient aged 27 suffering from a clear cell adenocarcinoma of the vagina which was related to her mother taking Diethylstilboestrol or Distilbene (DES) during her pregnancy. This young woman presented with pulmonary metastases for which several trials of chemotherapy ended in failure. The case raises several problems amongst which are epidemiologies of cancers induced by Diethylstilboestrol (DES), their prognosis as well as the therapeutic strategies at the time of diagnosis and the recurrences which occur as metastases.
authors.affiliation: Service de Pneumologie, Hôpital de la Croix-Rousse, Lyon.
authors.forename: P
authors.initials: P
authors.lastname: Nesme
authors.forename: J Y
authors.initials: JY
authors.lastname: Bayle
authors.forename: M
authors.initials: M
authors.lastname: Pérol
authors.forename: P
authors.initials: P
authors.lastname: Mathevet
authors.forename: D
authors.initials: D
authors.lastname: Vitrey
authors.forename: J C
authors.initials: JC
authors.lastname: Guérin
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D000328:Adult; D001706:Biopsy; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure; D014625:Vaginal Neoplasms / Q000139:chemically induced* / Q000473:pathology*
chemical_list: D004054:Diethylstilbestrol
vernacular_title: Métastases pulmonaires d'un adénocarcinome vaginal à cellules claires hormon-induit.