Animal models of Alzheimer's Parkinson's and Huntington's disease. A minireview.
Animal studies have contributed significantly to deeper understanding of several neurodegenerative disorders but fully developed models are lacking. The best models to study motor, sensory and cognitive changes and the effects of therapeutic attempts are rodents and non-human primates. This review describes neuropharmacologic, neuroanatomic and behavioral features of animal models of Alzheimer's, Parkinson's and Huntington's disease.
Antal
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Department of Comparative Physiology, József Attila University of Sciences, Szeged, Hungary.
Bodis-Wollner
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D000544:Alzheimer Disease / Q000503:physiopathology*; D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology*; D010300:Parkinson Disease / Q000503:physiopathology*