title: [Present status in the development of new antineoplastic agents].
abstract: Since the end of the seventies in the development of anti-tumourous chemotherapeutic agents a certain stagnation can be observed. Only few new cytostatics were introduced into clinical practice. Although the last few years were not characterized by a basically new drug with an anti-tumourous effect, the range of cytostatics used was enriched by a major number of new cytostatics. Most of them are derivatives of drugs which proved useful in practice and which were prepared in order to enhance the anti-tumourous effect or to reduce the toxicity. The author summarizes information on these new cytostatics and initial clinical experience assembled with these drugs.
authors.affiliation: I. internk klinika 1, LF UK, Praha.
authors.forename: P
authors.initials: P
authors.lastname: Klener
mesh_terms: D000970:Antineoplastic Agents; D006801:Humans
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Soucasný stav vývoje nových protinádorových chemoterapeutik.