Correlation of asymmetry of visual field loss with optic disc topography in normal-tension glaucoma.
OBJECTIVE
To compare the differences in optic disc configuration with different stages of visual field loss in normal-tension glaucoma.


METHODS
Interocular pairwise comparisons.


METHODS
Glaucoma clinic of a teaching hospital.


METHODS
Thirteen patients with normal-tension glaucoma and asymmetric visual field loss of at least 2.5 dB in the mean defect of the visual field indexes.


METHODS
Areas under the optic disc profiles mapped from values for radial sections of the optic disc measured at intervals of 30 degrees and expressed as percentages of the area of a rectangle were obtained from stereophotographs with a computerized image analysis system. Visual fields were tested with automated perimetry (OCTOPUS), using program G1.


METHODS
Correlation analyses between the interocular differences in the areas under the optic disc profile and the interocular differences in the visual field indexes.


RESULTS
The correlation coefficients between the interocular differences in mean defect and those of the area under the optic disc profile in the superior to temporal sections ranged from -.71 to -.61 (.007 < P < .028). The interocular differences in loss variance correlated with the differences in the area under the optic disc profile in the superior section (r = -.61, P = .0252).


CONCLUSIONS
The differences in visual field loss between the two eyes in normal-tension glaucoma appear mainly to reflect morphometric changes in the superior half of the optic disc.
Nyman
K
K
Department of Ophthalmology, University of Helsinki, Finland.
Tomita
G
G
Raitta
C
C
Kawamura
M
M
D000368:Aged; D005260:Female; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology* / Q000503:physiopathology; D014786:Vision Disorders / Q000503:physiopathology*; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology*