title: Inhibition of salt-induced gustatory responses in the frog (Rana catesbeiana) by 5'-GMP.
abstract: Millimolar concentration of sodium 5'-guanylate (5'-GMP), a 'umami' substance, inhibited salt-induced gustatory neural responses, particularly tonic components, of the bullfrog when the tongue was adapted to a low salt (5 mM NaCl) solution but not when adapted to normal saline that contained 115 mM NaCl. The result suggests that 5'-GMP is a modulator of adaptation process in salt response in the bullfrog taste system.
authors.affiliation: Department of Physiology, Nagasaki University School of Dentistry, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Okada
authors.forename: T
authors.initials: T
authors.lastname: Sato
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D006157:Guanosine Monophosphate / Q000494:pharmacology*; D007002:Hypoglossal Nerve / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D011892:Rana catesbeiana; D012965:Sodium Chloride / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D013649:Taste / Q000187:drug effects* / Q000502:physiology; D014059:Tongue / Q000294:innervation / Q000502:physiology
chemical_list: D012965:Sodium Chloride; D006157:Guanosine Monophosphate