title: A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast.
abstract: A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.
authors.affiliation: Department of Cell Biology, Stanford University School of Medicine, CA 94305.
authors.forename: B R
authors.initials: BR
authors.lastname: Cairns
authors.forename: Y J
authors.initials: YJ
authors.lastname: Kim
authors.forename: M H
authors.initials: MH
authors.lastname: Sayre
authors.forename: B C
authors.initials: BC
authors.lastname: Laurent
authors.forename: R D
authors.initials: RD
authors.lastname: Kornberg
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics / Q000302:isolation & purification; D001483:Base Sequence; D002868:Chromosomal Proteins, Non-Histone; D004265:DNA Helicases; D017931:DNA Primers / Q000235:genetics; D004271:DNA, Fungal / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics / Q000302:isolation & purification; D005656:Fungal Proteins / Q000235:genetics* / Q000302:isolation & purification*; D005800:Genes, Fungal; D046911:Macromolecular Substances; D008969:Molecular Sequence Data; D009687:Nuclear Proteins; D000071796:SMARCB1 Protein; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors / Q000235:genetics / Q000302:isolation & purification; D014158:Transcription, Genetic
chemical_list: D002868:Chromosomal Proteins, Non-Histone; D017931:DNA Primers; D004271:DNA, Fungal; D004268:DNA-Binding Proteins; D005656:Fungal Proteins; D046911:Macromolecular Substances; D009687:Nuclear Proteins; D000071796:SMARCB1 Protein; C513266:SMARCB1 protein, human; C066190:SNF5 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; D000251:Adenosine Triphosphatases; C499333:SNF2 protein, S cerevisiae; D004265:DNA Helicases