[The effect of mast cells on the T-lymphocyte mechanisms of hemopoiesis regulation in inflammation].
It was shown on the model of acute infections peritonitis in mice that the inflammation induced in the absence of mast cells was characterized by increased T-lymphocyte accumulation and macrophage-activating factor production and, in case of Thy-1,2(+)-lymphocyte elimination from bone marrow cell suspension, by earlier suppression of colony-stimulating and erythropoietic activity production by adhering and non-adhering myelokaryocytes. The results indicate that the modulatory effect of mast cells on haematopoiesis in inflammation is due in many respects to T-lymphocyte inhibition.
Gol'dberg
E D
ED
Dygaĭ
A M
AM
Klimenko
N A
NA
Gumilevskiĭ
B Iu
BIu
Bogdashin
I V
IV
Sherstoboev
E Iu
EIu
D000208:Acute Disease; D000818:Animals; D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000276:immunology; D001853:Bone Marrow / Q000276:immunology; D001854:Bone Marrow Cells; D002448:Cell Adhesion; D003114:Colony-Forming Units Assay; D004927:Escherichia coli Infections / Q000503:physiopathology*; D006410:Hematopoiesis / Q000502:physiology*; D016215:Macrophage-Activating Factors / Q000096:biosynthesis; D008297:Male; D008407:Mast Cells / Q000502:physiology*; D008562:Membrane Glycoproteins / Q000276:immunology; D051379:Mice; D008808:Mice, Inbred CBA; D010538:Peritonitis / Q000503:physiopathology*; D013601:T-Lymphocytes / Q000502:physiology*; D018800:Thy-1 Antigens; D013997:Time Factors
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface; D016215:Macrophage-Activating Factors; D008562:Membrane Glycoproteins; D018800:Thy-1 Antigens
Vliianie tuchnykh kletok na T-limfotsitarnye mekhanizmy reguliatsii gempoéza pri vospalenii.