A nondepleting anti-rat CD4 monoclonal antibody that suppresses T helper 1-like but not T helper 2-like intragraft lymphokine secretion induces long-term survival of renal allografts.
Siegling
A
A
Institute for Medical Immunology, Humboldt-University Berlin, Germany.
Lehmann
M
M
Riedel
H
H
Platzer
C
C
Brock
J
J
Emmrich
F
F
Volk
H D
HD
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D000917:Antibody Formation; D001483:Base Sequence; D015704:CD4 Antigens / Q000276:immunology*; D002874:Chromosome Mapping; D016207:Cytokines / Q000235:genetics; D006085:Graft Survival / Q000276:immunology; D007150:Immunohistochemistry; D007518:Isoantibodies / Q000276:immunology; D016030:Kidney Transplantation / Q000276:immunology* / Q000473:pathology; D008222:Lymphokines / Q000378:metabolism*; D008969:Molecular Sequence Data; D051381:Rats; D011919:Rats, Inbred Strains; D011920:Rats, Inbred WF; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D014158:Transcription, Genetic
D000911:Antibodies, Monoclonal; D015704:CD4 Antigens; D016207:Cytokines; D007518:Isoantibodies; D008222:Lymphokines