title: [Chronic beta-stimulant therapy: a possible etiopathogenic factor for hypertrophic cardiomyopathy].
abstract: We herein report the case of a 37-year-old woman, referred to our Unit because of atypical chest pain, negative T waves in leads V1-6 and medio-apical hypertrophic cardiomyopathy, diagnosed by two-dimensional echocardiography. The patient suffered from status asthmaticus and consequently had been treated for a twenty year period with beta-adrenoceptor stimulating agents, corticosteroids, theophylline. No coronary stenosis was revealed by coronary angiography. The results of electrocardiographic and two-dimensional echocardiographic investigations, performed after interruption of beta-stimulations, showed a regression of hypertrophic cardiomyopathy. We suggest that hypertrophic cardiomyopathy could be induced by beta-adrenergic stimulation.
authors.affiliation: U.T.I.C., Ospedale Civile, Teramo.
authors.forename: G
authors.initials: G
authors.lastname: Speca
authors.forename: A
authors.initials: A
authors.lastname: Core
authors.forename: L
authors.initials: L
authors.lastname: Pardi
mesh_terms: D000318:Adrenergic beta-Agonists / Q000009:adverse effects*; D000328:Adult; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D002312:Cardiomyopathy, Hypertrophic / Q000139:chemically induced* / Q000175:diagnosis; D004359:Drug Therapy, Combination; D004452:Echocardiography / Q000187:drug effects; D004562:Electrocardiography / Q000187:drug effects; D004630:Emergencies; D005260:Female; D006801:Humans
chemical_list: D000318:Adrenergic beta-Agonists
vernacular_title: Terapia cronica con beta-stimolanti: un possibile fattore etiopatogenetico per la cardiomiopatia ipertrofica.