title: One-step conversion of amino acids into N-menthyloxycarbonyl alkyl ester derivatives for chiral gas chromatography.
abstract: Amino acids dissolved in aqueous methanol (or ethanol) and treated with optically active menthyl chloroformate were converted into N-menthyloxycarbonyl methyl (or ethyl) ester derivatives within a few minutes at room temperature. The obtained diastereomeric derivatives, with the exception of arginine and histidine, had suitable gas chromatographic properties allowing enantiomeric analysis of a large number of proteinogenic and synthetic amino acids.
authors.affiliation: INSERM U 58, Montpellier, France.
authors.forename: N
authors.initials: N
authors.lastname: Domergue
authors.forename: M
authors.initials: M
authors.lastname: Pugniere
authors.forename: A
authors.initials: A
authors.lastname: Previero
mesh_terms: D000478:Alkylation; D000596:Amino Acids / Q000737:chemistry*; D002849:Chromatography, Gas; D004952:Esters; D005561:Formates; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D004952:Esters; D005561:Formates; C059663:menthyl chloroformate