title: Primary biliary cirrhosis. Sole presentation with rampant dental caries.
abstract: A 55-year-old woman was referred by her general dental practitioner for management of rampant dental caries of recent onset. Examination revealed a very dry mouth, angular stomatitis, and multiple carious lesions. Labial salivary gland biopsy showed features consistent with Sjögren's syndrome. Hematologic investigations showed antimitochondrial antibodies at a titer of 1 in 320, highly suggestive of primary biliary cirrhosis that was confirmed by liver biopsy.
authors.affiliation: University Department of Oral Medicine, Pathology and Microbiology, Bristol Dental School and Health, UK.
authors.forename: A
authors.initials: A
authors.lastname: Richards
authors.forename: J
authors.initials: J
authors.lastname: Rooney
authors.forename: S
authors.initials: S
authors.lastname: Prime
authors.forename: C
authors.initials: C
authors.lastname: Scully
mesh_terms: D001323:Autoantibodies / Q000097:blood; D003731:Dental Caries / Q000209:etiology*; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications*; D008875:Middle Aged; D008930:Mitochondria, Liver / Q000276:immunology; D014987:Xerostomia / Q000209:etiology*
chemical_list: D001323:Autoantibodies