Indirect excitatory actions of histamine on isolated chicken oesophagus.
The histamine-induced contraction on chicken oesophagus was antagonised non-competitively by atropine, hexamethonium, cocaine, methysergide, indomethacin, theophylline and verapamil. Physostigmine slightly potentiated the excitatory action of histamine. These results indicate that histamine excreted its excitatory action by involving a number of mechanisms as suggested in guinea pig oesophagus.
Kalra
A K
AK
Department of Pharmacology, CCS Harvana Agricultural University, Hisar, India.
Verma
S P
SP
Garg
S K
SK
Uppal
R P
RP
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002645:Chickens; D004947:Esophagus / Q000187:drug effects* / Q000502:physiology; D005260:Female; D006632:Histamine / Q000494:pharmacology*; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D010830:Physostigmine / Q000494:pharmacology; D013806:Theophylline / Q000494:pharmacology
D001285:Atropine; D006632:Histamine; D010830:Physostigmine; D013806:Theophylline