New application for the quantitation of cocaine base by gas chromatography.
The analysis of cocaine base is a major part of the forensic drug chemist's workload. Simplifying quantitative methodology can assist the drug chemist. Methods currently employed for quantitation of cocaine base utilize either an internal standard or a direct comparison. This gas chromatographic method for the quantitation of cocaine base employs a non-controlled reference standard and linear transformations. As a result, cocaine base can be quantitated by a single injection of a solution containing the analyte and a non-controlled reference standard of known concentration. Use of this methodology would minimize time expenditures, lower exposure to hazardous solvents and reduce expense of procuring difficult-to-obtain controlled reference standards while limiting detector response variations that can occur with multiple injections.
Krueger
S T
ST
Drug Enforcement Administration, Mid-Atlantic Laboratory, Washington, D.C.
D000473:Alkanes / Q000032:analysis; D002138:Calibration / Q000592:standards; D002849:Chromatography, Gas / Q000379:methods*; D003042:Cocaine / Q000032:analysis*; D013287:Illicit Drugs / Q000737:chemistry; D015203:Reproducibility of Results; D012601:Scopolamine / Q000032:analysis
D000473:Alkanes; D013287:Illicit Drugs; C050821:eicosane; D012601:Scopolamine; D003042:Cocaine