alpha-Hydroxyaldehydes, products of lipid peroxidation.
Besides the well known products of lipid peroxidation, 4-hydroxy-2-nonenal, saturated and unsaturated aldehydes, 2-hydroxy-heptanal was found to be a major aldehydic product of lipid peroxidation (LPO) of n-6 fatty acids (linoleic acid 18:2, arachidonic acid 20:4). 2-Hydroxyhexanal is produced also, but only in much lower yield. 2-Hydroxyalkanales with 8,9,10 and 11 C-atoms are derived from hydroperoxides of oleic acid. An oxidation product of all unsaturated fatty acids is glyoxal. Analyses were performed after aldehyde specific derivatization reactions by GC-MS.
Loidl-Stahlhofen
A
A
Lehrstuhl Organische Chemie I Universität Bayreuth, Germany.
Spiteller
G
G
D000447:Aldehydes / Q000032:analysis / Q000378:metabolism*; D016718:Arachidonic Acid / Q000378:metabolism; D002855:Chromatography, Thin Layer; D005227:Fatty Acids / Q000378:metabolism; D008401:Gas Chromatography-Mass Spectrometry; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000378:metabolism; D015227:Lipid Peroxidation; D019301:Oleic Acid; D009829:Oleic Acids / Q000378:metabolism; D010084:Oxidation-Reduction
D000447:Aldehydes; D005227:Fatty Acids; D008041:Linoleic Acids; D009829:Oleic Acids; D016718:Arachidonic Acid; D019301:Oleic Acid; D019787:Linoleic Acid