Anesthetic management in epidermolysis bullosa: review of 129 anesthetic episodes in 32 patients.
BACKGROUND
Anesthetic and monitoring instrumentations such as endotracheal intubation may cause skin and mucosal damage with potentially serious consequences in patients with epidermolysis bullosa (EB).


OBJECTIVE
This study defines the risks of skin and mucosal damage from anesthetic and monitoring techniques in patients with EB and formulates management guidelines.


METHODS
We retrospectively analyzed the outcome of 129 anesthetic episodes in 32 patients with various types of EB.


RESULTS
Serious complications did not occur in any patient with EB from the use of endotracheal intubation, face mask, nerve blocks, local anesthetics, and intravenous or intramuscular anesthetic agents.


CONCLUSIONS
With appropriate precautions, patients with EB can undergo standard anesthetic techniques with only minor and infrequent complications.
Lin
A N
AN
Laboratory for Investigative Dermatology, Rockefeller University, New York, NY 10021.
Lateef
F
F
Kelly
R
R
Rothaus
K O
KO
Carter
D M
DM
D000293:Adolescent; D000328:Adult; D000758:Anesthesia / Q000009:adverse effects* / Q000379:methods; D002648:Child; D002675:Child, Preschool; D004820:Epidermolysis Bullosa; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000009:adverse effects; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative