title: Collagen alterations in adipose autografts.
abstract: The author describes the collagen alterations in adipose tissue autografts as evaluated by the Picrosirius red stain used with polarized light microscopy. Four female patients--candidates for classical abdomino-plasty--previously had adipose tissue autografts at the infraumbilical region. The grafting intervals were 60, 30, 21, 15, 12, 8, and 5 days prior to the abdominoplasty. The findings demonstrate a type I collagen capsule circumscribing the graft, besides several alterations in the synthesis, degradation, and remodeling of type I and type III collagen within the transplanted tissue. These alterations evolved in bands from the periphery to the central region of the graft disclosing a clear sequence of events. The completion of this process, from the collagen synthesis to its degradation, depends on the total volume injected at a single point and may take a few months to one year or more.
authors.forename: C A
authors.initials: CA
authors.lastname: Carpaneda
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery; D000273:Adipose Tissue / Q000166:cytology / Q000378:metabolism* / Q000637:transplantation*; D003094:Collagen / Q000378:metabolism*; D005260:Female; D006801:Humans; D013518:Surgery, Plastic
chemical_list: D003094:Collagen