Characterization of asbestos fibers in pleural tissue from 21 cases of mesothelioma.
Pleural biopsies from 21 patients with pleural mesothelioma and different asbestos exposure were analyzed by means of analytical electron microscopy with the aim of investigating the presence, quantity, types and sizes of asbestos fibers in pleural tissue. The majority of fibers found consisted of ultrathin (< 0.3 micron) and short (< 5 microns) fibers regardless of asbestos types and subject exposure. Concentrations appeared to be poorly related to the estimated exposure level. Fiber dimensions appeared to be the most important characteristic which determined their translocation in the pleural region.
Paoletti
L
L
Department of Ultrastructures, Istituto Superiore di Sanità, Rome, Italy.
Falchi
M
M
Batisti
D
D
Zappa
M
M
Chellini
E
E
Biancalani
M
M
D000328:Adult; D000368:Aged; D001194:Asbestos / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000737:chemistry*; D008875:Middle Aged; D009784:Occupational Diseases; D016273:Occupational Exposure; D010997:Pleural Neoplasms / Q000737:chemistry*
D001194:Asbestos