[Effects of glucocorticosteroids on the fat metabolism and liver function in nonpregnant, nonlactating cows].
Following a five-day course of prednisolone (200 mg/d) the glucose, urea and insulin concentrations in the blood plasma as well as the glycogen content in the liver increased significantly in five nonpregnant, nonlactating cows compared with five control animals. In both groups the FFA, bilirubin and beta-OH-butyrate concentrations, the ASAT activities as well as the liver lipid concentration did not change. Under these conditions prednisolone does not stimulate lipolysis, nor does it disturb liver function in cows.
Fürll
M
M
Medizinischen Tierklinik, Veterinärmedizinischen Fakultät, Universität Leipzig.
Knobloch
B
B
D020155:3-Hydroxybutyric Acid; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D002417:Cattle / Q000502:physiology*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D005990:Glycerol / Q000097:blood; D006885:Hydroxybutyrates / Q000097:blood; D007328:Insulin / Q000097:blood; D050356:Lipid Metabolism; D008066:Lipolysis / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000502:physiology; D008112:Liver Glycogen / Q000378:metabolism; D011239:Prednisolone / Q000494:pharmacology*; D014508:Urea / Q000097:blood
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D006885:Hydroxybutyrates; D007328:Insulin; D008112:Liver Glycogen; D014508:Urea; D011239:Prednisolone; D001219:Aspartate Aminotransferases; D005990:Glycerol; D001663:Bilirubin; D020155:3-Hydroxybutyric Acid
Glukokortikosteroidwirkungen auf den Fettstoffwechsel und die Leberfunktion bei güsten, nichtlaktierenden Kühen.