title: Hypoglycemic effect of Ocimum sanctum leaf extract in normal and streptozotocin diabetic rats.
abstract: Oral administration of alcoholic extract of leaves of O. sanctum led to marked lowering of blood sugar level in normal, glucose fed hyperglycemic and streptozotocin induced diabetic rats. Further the extract potentiated the action of exogenous insulin in normal rats. The activity of the extract was 91.55 and 70.43% of that of tolbutamide in normal and diabetic rats respectively.
authors.affiliation: Biometry Research Unit, Indian Statistical Institute, Calcutta.
authors.forename: R R
authors.initials: RR
authors.lastname: Chattopadhyay
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D005260:Female; D007004:Hypoglycemic Agents / Q000494:pharmacology; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D014044:Tolbutamide / Q000494:pharmacology
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D014044:Tolbutamide