title: [Infection in patient with malignant disease].
abstract: The rate of infection in patients with malignant disease was significantly high than that of patients with benign disease. Enterococcus spp. was the most predominant organism isolated from patients with malignant disease, followed by Staphylococcus spp., Pseudomonas spp., Enterobacter spp. and Klebsiella spp. in order. From patients with benign disease, E. coli was the most predominant organism, followed by Gram negative anaerobes, and Klebsiella spp.. The rate of postoperative infection in the patients with malignant biliary disease was significantly high than that without a risk factor. The rates of bacterial isolation from intraoperative bile culture and wound swab were significantly higher in patient with malignant disease. These findings suggest that the utmost care should be exercised in patients with malignant disease in order to prevent intraoperative contamination with prophylactic antibiotic therapy covering the bacteria isolated from the bile.
authors.affiliation: First Department of Surgery, Nagoya City University Medical School.
authors.forename: N
authors.initials: N
authors.lastname: Shinagawa
mesh_terms: D000368:Aged; D001424:Bacterial Infections / Q000209:etiology*; D001661:Biliary Tract Neoplasms / Q000601:surgery*; D002779:Cholestasis / Q000209:etiology / Q000628:therapy; D004322:Drainage; D006801:Humans; D011183:Postoperative Complications; D012307:Risk Factors