Morphological and structural characteristics of the myopathic bone.
The aim of the present paper was to study the myopathic bone both from the morphological and structural viewpoints. To this end, samples from 8 patients affected by different neuromuscular diseases (DMD, SMA and CMD) have been examined. Thus, by SEM analysis a quantitative reduction of the trabeculae and an increase in porosity of the myopathic bone were found and also, by diffractometric analysis, the presence of pathologic crystalline phases (beta-TCP and beta-TCP-Mg).
Mongiorgi
R
R
Department of Mineralogical Sciences, University of Bologna.
Ballestrazzi
A C
AC
Granata
C
C
Bertocchi
G
G
Maggi
G
G
Gnudi
S
S
Gandolfi
M G
MG
D000293:Adolescent; D000328:Adult; D001842:Bone and Bones / Q000737:chemistry / Q000648:ultrastructure*; D002130:Calcium Phosphates / Q000032:analysis*; D002648:Child; D003460:Crystallization; D006801:Humans; D008274:Magnesium / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D009134:Muscular Atrophy, Spinal / Q000473:pathology*; D009136:Muscular Dystrophies / Q000145:classification / Q000151:congenital / Q000473:pathology*; D012600:Scoliosis / Q000473:pathology; D013054:Spectrophotometry, Atomic; D014961:X-Ray Diffraction
D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate; D008274:Magnesium; C018392:tricalcium phosphate