The association of cleft lip and palate with Aicardi syndrome.
In summary, Aicardi syndrome is defined by its tetrad of infantile spasms, agenesis of the corpus callosum, mental retardation, and chorioretinal lacunae. We report a case of Aicardi syndrome with associated cleft lip and palate. This is an infrequent finding that is present in approximately 3 percent of reported cases. Plastic surgeons should be aware of this association when treating patients with cleft lip and palate.
Umansky
W S
WS
Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Calif.
Neidich
J A
JA
Schendel
S A
SA
D001921:Brain / Q000473:pathology; D002828:Choristoma / Q000473:pathology; D002829:Choroid / Q000002:abnormalities*; D002971:Cleft Lip / Q000473:pathology*; D002972:Cleft Palate / Q000473:pathology*; D003337:Corpus Callosum / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008607:Intellectual Disability / Q000473:pathology*; D009918:Orbital Neoplasms / Q000473:pathology; D012160:Retina / Q000002:abnormalities*; D013036:Spasms, Infantile / Q000473:pathology*; D013577:Syndrome