title: A case of uveitis associated with idiopathic retroperitoneal fibrosis.
abstract: We treated a patient with nongranulomatous panuveitis associated with idiopathic retroperitoneal fibrosis who had symptoms of abdominal pain, severe fever, leg edema, and blurred vision. A high C-reactive protein level, a high erythrocyte sedimentation rate, anemia, and abnormalities of the immune system were seen. Retrograde pyelography disclosed persistent ureteral obstruction. A computed tomographic scan and magnetic resonance imaging showed a dense plaque of fibrous tissue around the kidney and hydronephrosis. Biopsy disclosed fibrosis infiltrated with lymphocytes, plasma cells, histiocytes, and eosinophils. A moderate degree of cellular inflammation in the anterior chamber and cystoid macular edema were present at ocular examination. We believe idiopathic retroperitoneal fibrosis to be a new cause of uveitis of suspected autoimmune origin.
authors.affiliation: Department of Ophthalmology, Mie University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Doi
authors.forename: Y
authors.initials: Y
authors.lastname: Uji
mesh_terms: D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008269:Macular Edema / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D015864:Panuveitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012185:Retroperitoneal Fibrosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging; D014567:Urography; D014786:Vision Disorders / Q000175:diagnosis
chemical_list: D005938:Glucocorticoids; D002097:C-Reactive Protein