title: Medical consequences of cocaine.
abstract: Cocaine use among middle-class North Americans increased dramatically during the 1980s. Medical complications involve almost every organ system and are produced by intense vasoconstriction. Managing cocaine-induced disease requires careful identification and the use of alpha-adrenergic blocking agents, in addition to standard therapy and referral to specialists to manage cocaine withdrawal.
authors.affiliation: Dalhousie University, Halifax.
authors.forename: J D
authors.initials: JD
authors.lastname: Gray
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000328:Adult; D003042:Cocaine / Q000009:adverse effects* / Q000378:metabolism; D015897:Comorbidity; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009656:North America / Q000453:epidemiology; D011247:Pregnancy; D012017:Referral and Consultation; D012940:Social Problems; D013375:Substance Withdrawal Syndrome / Q000517:prevention & control*; D019966:Substance-Related Disorders / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy
chemical_list: D000317:Adrenergic alpha-Antagonists; D003042:Cocaine