title: Low-dose aspirin in pregnancy: changes in patterns of prescription in The Netherlands.
abstract: OBJECTIVE
  To describe patterns of prescription in the Netherlands of low-dose aspirin in pregnancy.
  
  
  METHODS
  Anonymous written inquiry in 1989 and 1991.
  
  
  METHODS
  Gynecologists in the Netherlands (619 in 1989 and 618 in 1991), practicing in training and non-training hospitals.
  
  
  METHODS
  Prescription rates for prevention of pregnancy-induced hypertension and fetal growth retardation, or for intention to treat.
  
  
  RESULTS
  The response rates were 52% in 1989 and 58% in 1991, covering approximately 61% and 62%, respectively, of the practicing gynecologists in the Netherlands. The use for prevention increased from 53% to 79% and for therapeutic intentions from 25% to 48%.
  
  
  CONCLUSIONS
  The prescription rate for low-dose aspirin increased markedly from 1989 to 1991, without evidence for its benefit from the literature published in the same time period.
authors.affiliation: Institute of Obstetrics and Gynecology, Erasmus University School of Medicine and Health Sciences, Rotterdam, The Netherlands.
authors.forename: H A
authors.initials: HA
authors.lastname: Bremer
authors.forename: H C
authors.initials: HC
authors.lastname: Wallenburg
mesh_terms: D001241:Aspirin / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005317:Fetal Growth Retardation / Q000517:prevention & control*; D006801:Humans; D006973:Hypertension / Q000517:prevention & control*; D009426:Netherlands; D011225:Pre-Eclampsia / Q000517:prevention & control; D011247:Pregnancy; D011248:Pregnancy Complications / Q000517:prevention & control*; D011256:Pregnancy Outcome
chemical_list: D001241:Aspirin