title: Ethylene vinylacetate copolymer particles dissolved in polyvinyl alcohol (2,000-mer) solution as an embolic material for vascular anomalies. A preliminary study.
abstract: We have prepared a new material for embolisation: ethylene vinylacetate copolymer dissolved in polyvinyl alcohol. When in contact with blood, polyvinyl alcohol rapidly becomes a soft gel, which is accompanied by wedging of the ethylene vinylacetate copolymer. We analysed the histopathology of intra-arterial microemboli in rats, after intracarotid injection of this material. We confirmed that it was applicable to embolisation for neurosurgical treatment.
authors.affiliation: Department of Neurosurgery, Osaka University Medical School, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Kinoshita
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Yamazaki
authors.forename: M
authors.initials: M
authors.lastname: Taneda
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
mesh_terms: D000818:Animals; D001165:Arteriovenous Malformations / Q000628:therapy; D002343:Carotid Artery, Internal / Q000473:pathology; D002648:Child; D004621:Embolization, Therapeutic; D006801:Humans; D007269:Injections, Intra-Arterial; D002538:Intracranial Arteriovenous Malformations / Q000628:therapy; D008297:Male; D011142:Polyvinyl Alcohol / Q000008:administration & dosage; D011145:Polyvinyls / Q000008:administration & dosage; D051381:Rats; D017208:Rats, Wistar
chemical_list: D011145:Polyvinyls; C016438:ethylenevinylacetate copolymer; D011142:Polyvinyl Alcohol