[A comparative study of the antenatal action of inducers of the mono-oxygenase system and of dexamethasone on the body indices of full-term newborn rat pups].
Experiments on newborn rats demonstrated that hepatic monooxygenase system inductors, such as phenobarbital, benzonal, zixorin, increased their body weight, absolute and relative mass of newborn lungs when applied antenatally in contrast to dexamethasone which decreased the above parameters. The inductors increased pulmonary and hepatic phospholipid levels, which suggests that they are superior to dexamethasone in this respect.
Nadzhimutdinov
K N
KN
Mavlianov
I R
IR
Kabulov
Sh M
ShM
Lopatko
O V
OV
Umarova
Z F
ZF
Babikova
R Kh
RKh
D000818:Animals; D000831:Animals, Newborn; D001463:Barbiturates / Q000494:pharmacology*; D001559:Benzhydryl Compounds / Q000494:pharmacology*; D003907:Dexamethasone / Q000494:pharmacology*; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010105:Oxygenases / Q000096:biosynthesis / Q000187:drug effects*; D010634:Phenobarbital / Q000494:pharmacology*; D010743:Phospholipids / Q000378:metabolism; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats
D001463:Barbiturates; D001559:Benzhydryl Compounds; D010743:Phospholipids; D003907:Dexamethasone; D010105:Oxygenases; C016914:flumecinol; C002915:benzobarbital; D010634:Phenobarbital
Sravnitel'noe izuchenie antenatal'nogo deĭstviia induktorov monooksigenaznoĭ sistemy i deksametazona na nekotorye pokazateli organizma donoshennykh novorozhdennykh krysiat.