Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2.
Beaton
H G
HG
Department of Medicinal Chemistry, Fisons plc, Loughborough, Leicestershire, U.K.
Bennion
C
C
Connolly
S
S
Cook
A R
AR
Gensmantel
N P
NP
Hallam
C
C
Hardy
K
K
Hitchin
B
B
Jackson
C G
CG
Robinson
D H
DH
D000818:Animals; D001559:Benzhydryl Compounds / Q000737:chemistry* / Q000494:pharmacology; D001665:Binding Sites; D001792:Blood Platelets / Q000201:enzymology; D015195:Drug Design; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010179:Pancreas / Q000201:enzymology; D010741:Phospholipases A / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013329:Structure-Activity Relationship; D013552:Swine; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology
D001559:Benzhydryl Compounds; C086203:FPL 67047XX; D005680:gamma-Aminobutyric Acid; D010741:Phospholipases A