Anti-tau-positive glial fibrillary tangles in the brain of postencephalitic parkinsonism of Economo type.
Tau-immunoreactive astrocytes have been reported in the brain of progressive supranuclear palsy (PSP) and are referred to as glial fibrillary tangles (GFTs). We found a number of GFTs in the heavily degenerated brain region in four cases of postencephalitic parkinsonism of Economo (PPE) with a clinical history of over a half-century. GFTs had the appearance of tufts of spider-like radiating fibers or small thorn-like feature by Gallyas-Braak method and also by anti-tau immunostaining.
Ikeda
K
K
Department of Neuropathology, Tokyo Institute of Psychiatry, Japan.
Akiyama
H
H
Kondo
H
H
Ikeda
K
K
D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D016874:Neurofibrillary Tangles / Q000276:immunology / Q000378:metabolism*; D009457:Neuroglia / Q000276:immunology / Q000378:metabolism*; D010301:Parkinson Disease, Postencephalitic / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D016875:tau Proteins / Q000276:immunology / Q000378:metabolism*
D016875:tau Proteins