[Catecholamine provision and the morphofunctional characteristics of the lymph nodes with different special purposes in acute benzpyrene poisoning].
Using fluorescent histochemical methods of catecholamines detection microfluorometry, morphometry, and classical cytological technique the catecholamine level, the density of adrenergic nerve fibers and cytological composition of the lymph nodes of different localization were studied in rats in health and after intraperitoneal injection of benz(a)pyrene. It has been revealed that exposure to benzpyren leads to decrease of catecholamine level and of the density of adrenergic innervation of abdominal lymph nodes and is accompanied with structural changes (decrease of corticomedullary index as a result of augmentation of the area of medullary sinuses and medullary cords) and cytological content of these organs (increase of plasmocyte counts in medullary cords). The degree of structural reconstructions depends on the primary status of organs and its typological characteristics. Catecholamine-depending reconstruction of the lymph nodes is connected with the place and method of toxic agent injection.
Izranov
V A
VA
D000208:Acute Disease; D000818:Animals; D001580:Benzopyrenes / Q000506:poisoning*; D002395:Catecholamines / Q000378:metabolism*; D003592:Cytophotometry; D006651:Histocytochemistry; D008198:Lymph Nodes / Q000378:metabolism* / Q000473:pathology; D008856:Microscopy, Fluorescence; D011041:Poisoning / Q000378:metabolism / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar
D001580:Benzopyrenes; D002395:Catecholamines
Katekholaminobespechenie i morfofunktsional'naia kharakteristika limfaticheskikh uzlov razlichnoĭ spetsializatsii v usloviiakh ostroĭ intoksikatsii benzpirenom.