title: Data management in multi-center clinical trials and the role of a nation-wide computer network. A 5 year evaluation.
abstract: Multidisciplinary collaboration in multi-center trials needs a formalized data management structure to ensure true progress monitoring and high quality research data. Cadans, a customized facility for data management, related to the Interuniversity Cardiology Institute of the Netherlands, designed a computer-based data management system for multidisciplinary multi-center collaborative research projects. In this paper we describe the system and the role of integrated access to research databases on a data network. Areas of concern are also discussed.
authors.affiliation: Interuniversity Cardiology Institute of The Netherlands, Utrecht.
authors.forename: M G
authors.initials: MG
authors.lastname: Gerritsen
authors.forename: O E
authors.initials: OE
authors.lastname: Sartorius
authors.forename: F M
authors.initials: FM
authors.lastname: vd Veen
authors.forename: G T
authors.initials: GT
authors.lastname: Meester
mesh_terms: D002309:Cardiology; D002986:Clinical Trials as Topic; D003195:Computer Communication Networks; D003199:Computer Systems; D003628:Database Management Systems; D005069:Evaluation Studies as Topic; D006801:Humans; D015337:Multicenter Studies as Topic; D009426:Netherlands; D012577:Schools, Medical; D012985:Software Design