title: [Laser therapy of villous rectocolonic tumors. Evaluation of results by multivariate analysis].
abstract: One hundred and twenty-four patients (mean age: 70 years) with a villous tumour of the rectum (n = 98) or the colon (n = 26) were treated by laser therapy from 1985 to 1991. Initial complete eradication was obtained in 93.5% of cases with a median time of 16 months. Using multivariate analysis, the tumor size (> 4 cm) only was predictive of eradication (P < 0.001). At 6 and 12 months, the actuarial eradication rates were 91 and 98% for small tumours versus 45 and 74% for larger tumours respectively. The actuarial recurrence rates were 10.5, 23, and 37% at 6, 12 and 24 months, and no longer increased after 3 years. No predictive factor of recurrence was isolated by multivariate analysis. Seven complications (5.6%) and 4 malignant transformations (3.4%) occurred. This study confirms the efficiency and low morbidity of laser therapy, especially in patients with small tumors, less than 4 cm in size.
authors.affiliation: Service d'Hépato-Gastroentérologie, CHRU, Angers.
authors.forename: O
authors.initials: O
authors.lastname: Ruget
authors.forename: P
authors.initials: P
authors.lastname: Burtin
authors.forename: A K
authors.initials: AK
authors.lastname: Ben Bouali
authors.forename: N
authors.initials: N
authors.lastname: D'Aubigny
authors.forename: J
authors.initials: J
authors.lastname: Boyer
mesh_terms: D018253:Adenoma, Villous / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications; D012004:Rectal Neoplasms / Q000601:surgery*; D017211:Treatment Failure
vernacular_title: Traitement par laser des tumeurs villeuses rectocoliques. Evaluation des résultats par analyse multifactorielle.