title: Morphological and structural characteristics of the myopathic bone.
abstract: The aim of the present paper was to study the myopathic bone both from the morphological and structural viewpoints. To this end, samples from 8 patients affected by different neuromuscular diseases (DMD, SMA and CMD) have been examined. Thus, by SEM analysis a quantitative reduction of the trabeculae and an increase in porosity of the myopathic bone were found and also, by diffractometric analysis, the presence of pathologic crystalline phases (beta-TCP and beta-TCP-Mg).
authors.affiliation: Department of Mineralogical Sciences, University of Bologna.
authors.forename: R
authors.initials: R
authors.lastname: Mongiorgi
authors.forename: A C
authors.initials: AC
authors.lastname: Ballestrazzi
authors.forename: C
authors.initials: C
authors.lastname: Granata
authors.forename: G
authors.initials: G
authors.lastname: Bertocchi
authors.forename: G
authors.initials: G
authors.lastname: Maggi
authors.forename: S
authors.initials: S
authors.lastname: Gnudi
authors.forename: M G
authors.initials: MG
authors.lastname: Gandolfi
mesh_terms: D000293:Adolescent; D000328:Adult; D001842:Bone and Bones / Q000737:chemistry / Q000648:ultrastructure*; D002130:Calcium Phosphates / Q000032:analysis*; D002648:Child; D003460:Crystallization; D006801:Humans; D008274:Magnesium / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D009134:Muscular Atrophy, Spinal / Q000473:pathology*; D009136:Muscular Dystrophies / Q000145:classification / Q000151:congenital / Q000473:pathology*; D012600:Scoliosis / Q000473:pathology; D013054:Spectrophotometry, Atomic; D014961:X-Ray Diffraction
chemical_list: D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate; D008274:Magnesium; C018392:tricalcium phosphate