[Influence of viral infections in the pathogenesis of atherosclerosis].
The authors found a significant reduction of the suppressor function in carriers of the Australian antigen. This may contribute to a formation of immune complexes. Infection of rabbits with Herpes simplex virus resulted in an essentially enhanced development of experimental atherosclerosis against the background of a reduction of the suppressor function. These findings give evidence of the importance of viral infection in the development of atherosclerosis due to an inhibition of the suppressor function of T lymphocytes.
Gandsha
I M
IM
Institut für ärztliche Fortbildung, Kiew, Ukraine.
Fedotow
A F
AF
Swirid
L M
LM
D000328:Adult; D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology* / Q000276:immunology; D002353:Carrier State; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006561:Herpes Simplex / Q000150:complications* / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation; D011817:Rabbits; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D006514:Hepatitis B Surface Antigens
Uber die Bedeutung von Virusinfektionen in der Pathogenese der Atherosklerose.