Doppler measurement of breast vascularity in women under pharmacologic treatment of benign breast disease.
Breast vascularization was measured with an 8-MHz continuous wave Doppler pencil probe. Flow values were low in asymptomatic women and high in patients with severe pain or dysplastic changes. Mild treatment with a plant extract produced only a small decrease in breast vascularization. Treatment with norethisterone acetate showed a dose-dependent decrease in blood flow. A good response was seen with a dosage of 5 mg/d, and a dramatic decrease was seen when 10 mg/d was taken. These results showed a good correlation with the patients' symptoms.
Madjar
H
H
Department of Obstetrics and Gynecology, Albert Ludwigs University, Freiburg, Germany.
Vetter
M
M
Prömpeler
H
H
Breckwoldt
M
M
Pfleiderer
A
A
D000328:Adult; D001940:Breast / Q000098:blood supply*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use; D011372:Progestins / Q000627:therapeutic use; D012039:Regional Blood Flow; D016217:Ultrasonography, Mammary
D010936:Plant Extracts; D011372:Progestins; C012413:mastodynon