Molecular cloning and sequencing of porcine somatostatin receptor 2.
The porcine somatostatin receptor gene was isolated from a porcine genomic library. Based on the deduced amino acid sequence, this gene encodes a 369 amino acid protein with seven hydrophobic segments, a characteristic of G-protein coupled receptors, and shows only 13 amino acid difference (identity 96.5%, similarity 99.2%) in amino acid sequence from human somatostatin receptor 2. The data indicate that the amino acid sequence is highly conserved in pig, human, rat and mouse somatostatin receptor 2.
Matsumoto
K
K
First Department of Internal Medicine, School of Medicine, University of Tokushima, Japan.
Yokogoshi
Y
Y
Fujinaka
Y
Y
Zhang
C
C
Saito
S
S
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D017931:DNA Primers / Q000737:chemistry; D005796:Genes; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D017481:Receptors, Somatostatin / Q000737:chemistry / Q000235:genetics*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012995:Solubility; D013552:Swine
D017931:DNA Primers; D017481:Receptors, Somatostatin