[The stimulation of the growth and differentiation of the axons and dendrites of spinal cord neurons in tissue culture].
Study of stimulating effects of human umbilical cord blood serum supernatant of chicken embryo somatic muscle tissue, and dalargin on the differentiation of chick embryo spinal neurons under conditions of cultivation has revealed that the highest stimulating effect is exerted by human cord blood serum at increased concentration (20%), promoting intensive growth and differentiation of axons and dendrites of spinal neurons. The stimulating effect of the serum has also been observed during cultivation of individual explants, when the influence of the factor responsible for activation and direction of the growth of axons and dendrites during simultaneous cultivation of two explants is excluded.
Svanidze
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Museridze
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D000818:Animals; D001369:Axons / Q000187:drug effects* / Q000648:ultrastructure; D002454:Cell Differentiation / Q000187:drug effects; D002642:Chick Embryo; D003470:Culture Media; D046508:Culture Techniques; D003712:Dendrites / Q000187:drug effects* / Q000648:ultrastructure; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives / Q000494:pharmacology; D005312:Fetal Blood; D006133:Growth Substances / Q000494:pharmacology*; D006801:Humans; D009132:Muscles; D009414:Nerve Growth Factors / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects* / Q000648:ultrastructure; D013116:Spinal Cord / Q000187:drug effects* / Q000254:growth & development* / Q000648:ultrastructure; D013268:Stimulation, Chemical; D013997:Time Factors; D014020:Tissue Extracts / Q000494:pharmacology
D003470:Culture Media; D006133:Growth Substances; D009414:Nerve Growth Factors; D014020:Tissue Extracts; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Stimuliatsiia rosta i differentsirovki aksonov i dendritov neĭronov spinnogo mozga v tkanevoĭ kul'ture.