[D-Trp-6 gonadotropin analog releasing hormone (Decapeptyl-Depot)-- the drug of choice in central idiopathic precocious puberty].
The authors submit their experience with the treatment of idiopathic precocious central puberty in two girls with the GnRH analog (Decapeptyl-Depot, Ferring Co.). The drug was administered for one an a half and two years resp., 80 mg/kg once per month. Apart from the effect on gonadarche and thelarche the pubertal growth rate was reduced to a prepubertal level and the originally accelerated bone maturation was reduced.
Hníková
O
O
Klinika dĕtí a dorostu 3. LF UK, Praha.
Janecková
M
M
Finková
M
M
D002648:Child; D003692:Delayed-Action Preparations; D005260:Female; D006128:Growth / Q000187:drug effects; D006801:Humans; D011629:Puberty, Precocious / Q000188:drug therapy* / Q000503:physiopathology; D017329:Triptorelin Pamoate / Q000008:administration & dosage*
D003692:Delayed-Action Preparations; D017329:Triptorelin Pamoate
D-Trp-6 gonadotropin analog releasing hormon (Decapeptyl-Depot)--lék volby u centrální idiopatické predcasné puberty.