The effect of short term lithium treatment on the leukocyte, liver and muscle carbohydrate metabolism of guinea-pigs.
1. The effect of lithium treatment on the leukocyte, liver and muscle glycogen levels of guinea-pigs has been studied. 2. A 4-week treatment with lithium chloride (5 mmol/l i.p. in saline) increased leukocyte, liver and muscle glycogen and decreased blood glucose levels. 3. These results strongly suggest that a lithium-induced insulin-like effect may be related to the long term effect.
Altan
N
N
Department of Biochemistry, Faculty of Medicine, University of Gazi, Ankara, Turkey.
Engin
A
A
Hizel
N
N
Ongun
O
O
Cevik
C
C
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D050260:Carbohydrate Metabolism; D006003:Glycogen / Q000378:metabolism; D006168:Guinea Pigs; D007962:Leukocytes / Q000187:drug effects / Q000378:metabolism*; D008094:Lithium / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*
D001786:Blood Glucose; D008112:Liver Glycogen; D006003:Glycogen; D008094:Lithium