[Squamous cell carcinoma associated antigen levels in monitoring the response to surgical treatment for patients with esophageal carcinoma].
The serum levels of the squamous cell carcinoma associated antigen (SCCAg) were measured in 50 patients with esophageal carcinoma by immunoradiometric assay before and after surgery. 32 patients were subjected to curative surgery, 15 palliative operation, 3 exploratory thoracotomy. After curative surgery, the elevated level dropped rapidly to normal within 72 hours. The SCCAg levels showed statistical differences. In patients having palliative operation, the SCCAg levels declined but usually remained above the normal range. After exploratory thoracotomy, the SCCAg levels usually increased. Because SCCAg responded well to the effects of surgery, it was considered to be a very useful tumor marker in monitoring the response to surgical treatment for patients with esophageal carcinoma.
Zeng
L
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Department of Thoracic Surgery, Zhong Shan Hospital, Shanghai Medical University.
D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000097:blood / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015843:Serpins
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D015843:Serpins; C051072:squamous cell carcinoma-related antigen