(1-->3)-beta-D-glucan in indoor air, its measurement and in vitro activity.
The underlying mechanisms of the biological activity of (1-->3)-beta-D-glucan was investigated using macrophages from guinea pigs or mice. The results showed that these cells expressed (1-->3)-beta-D-glucan specific receptors on their surface, and that the release of TNF-alpha from cells was modulated by the presence of (1-->3)-beta-D-glucan.
Goto
H
H
Department of Pulmonary Diseases, Tokyo Metropolitan Komagome General Hospital, Japan.
Yuasa
K
K
Rylander
R
R
D016902:Air Pollution, Indoor / Q000032:analysis*; D000818:Animals; D002478:Cells, Cultured; D005936:Glucans / Q000032:analysis* / Q000494:pharmacology*; D006168:Guinea Pigs; D008264:Macrophages / Q000187:drug effects* / Q000502:physiology; D016676:Macrophages, Alveolar / Q000187:drug effects / Q000502:physiology; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000502:physiology; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects; D011956:Receptors, Cell Surface / Q000032:analysis / Q000502:physiology; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects* / Q000502:physiology; D047071:beta-Glucans
D005936:Glucans; D011956:Receptors, Cell Surface; D014409:Tumor Necrosis Factor-alpha; D047071:beta-Glucans; C033363:beta-1,3-glucan