title: Huntington's disease: recent progress in gene mapping and potential local application in Singapore.
abstract: Advances in the field of molecular genetics have made testing of individuals for the presence of certain genes possible. Programmes for testing families with Huntington's disease have been developed overseas but not locally. We outline our beginning attempts to make services such as prenatal exclusion testing and presymptomatic carrier detection available to Singapore families with Huntington's disease.
authors.affiliation: Neurology Unit, Singapore General Hospital.
authors.forename: M C
authors.initials: MC
authors.lastname: Wong
authors.forename: I S
authors.initials: IS
authors.lastname: Ng
mesh_terms: D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4; D015342:DNA Probes; D005819:Genetic Markers / Q000235:genetics; D005820:Genetic Testing; D006801:Humans; D006816:Huntington Disease / Q000235:genetics* / Q000517:prevention & control; D012150:Polymorphism, Restriction Fragment Length; D011296:Prenatal Diagnosis
chemical_list: D015342:DNA Probes; D005819:Genetic Markers