[The cross resistance to cytostatics of leukemia P388 cells with induced resistance to doxorubicin].
Using BDF1 mice it has been shown that P388 leukemia tumor cells with induced resistance to doxorubicin (P388/DX) were cross-resistant to daunomycin, carminomycin, actinomycin D, vincristine and mitomycin C. It has been shown that P388/DX leukemia tumor cells were sensitive to bleocina, bleomycitina, cyclophosphamide, 5 fluorouracil. It has been discussed the ways of cross-resistance of P388/DX leukemia tumor cells to cytostatic drugs.
Donenko
F V
FV
Sitdikova
S M
SM
Kabieva
A O
AO
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000037:antagonists & inhibitors*; D004317:Doxorubicin / Q000008:administration & dosage / Q000037:antagonists & inhibitors*; D004351:Drug Resistance; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388 / Q000188:drug therapy* / Q000401:mortality; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009368:Neoplasm Transplantation
D000970:Antineoplastic Agents; D004317:Doxorubicin
Perekrestnaia rezistentnost' k tsitostatikam kletok leĭkoza P388 s indutsirovannoĭ ustoĭchivost'iu k doksorubitsinu.