Immunohistochemical localization of gonadotropin-associated peptide (GAP) in the human hypothalamus.
GAP was immunohistochemically localized for the first time in the human hypothalamus. GAP-immunoreactivity was present in the cytoplasm of neuronal cells in the arcuate nucleus. GAP-immunoreactive nerve fibers were also present in the primary plexus around capillaries in the infundibular region. No GAP-immunoreactive neurons were detected in the paraventricular nuclei or supraoptic nuclei.
Andoh
N
N
Department of Pathology, Tohoku University School of Medicine, Sendai.
Ohtani
H
H
Satoh
I
I
Sasano
N
N
Mukada
T
T
Yanaihara
N
N
Nagura
H
H
D001111:Arcuate Nucleus of Hypothalamus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D006801:Humans; D007031:Hypothalamus / Q000378:metabolism*; D007150:Immunohistochemistry; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism; D011498:Protein Precursors / Q000378:metabolism*; D013495:Supraoptic Nucleus / Q000378:metabolism
D011498:Protein Precursors; C050502:gonadotropin releasing hormone associated peptide; D007987:Gonadotropin-Releasing Hormone