title: Use of therapeutic drug monitoring in pharmacoeconomics.
abstract: The use of therapeutic drug monitoring (TDM) for drugs with a narrow therapeutic range has contributed substantially to the literature. The pharmacoeconomics of this service for hospitalized patients has demonstrated significant hospital savings. Appropriate use of this pharmacy-based service has demonstrated savings, reduction in total length of hospitalization, and cost avoidance with aminoglycoside-induced nephrotoxicity. Use of a Clinical Pharmacokinetic Service (CPS) for inpatient theophylline therapy and outpatient anticonvulsant therapy documents the pharmacoeconomic benefits provided by this service to both in- and outpatients. This report will discuss current literature with regard to pharmacoeconomics and cost-benefit analysis of TDM.
authors.affiliation: Creighton University School of Pharmacy and Allied Health Professions, Omaha, Nebraska 68178.
authors.forename: C J
authors.initials: CJ
authors.lastname: Destache
mesh_terms: D003362:Cost-Benefit Analysis; D016903:Drug Monitoring / Q000191:economics*; D004358:Drug Therapy / Q000191:economics*; D017850:Economics, Pharmaceutical; D006801:Humans; D010607:Pharmacy Service, Hospital