title: Correction of Duncan's syndrome by allogeneic bone marrow transplantation.
abstract: Duncan's syndrome (X-linked lymphoproliferative disorder) is a fatal immunodeficiency syndrome of unknown aetiology and without cure. We show that allogeneic bone marrow transplantation can correct the lethal immune deficits in a patient with this syndrome. We suggest that the primary abnormality in Duncan's syndrome is in bone-marrow derived cells.
authors.affiliation: Department of Hematology/Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: L L
authors.initials: LL
authors.lastname: Williams
authors.forename: C M
authors.initials: CM
authors.lastname: Rooney
authors.forename: M E
authors.initials: ME
authors.lastname: Conley
authors.forename: M K
authors.initials: MK
authors.lastname: Brenner
authors.forename: R A
authors.initials: RA
authors.lastname: Krance
authors.forename: H E
authors.initials: HE
authors.lastname: Heslop
mesh_terms: D016026:Bone Marrow Transplantation; D002648:Child; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000601:surgery*; D008297:Male; D014184:Transplantation, Homologous