Irradiation of nonlymphoproliferative neoplasms of the nasal cavity and paranasal sinuses in 16 cats.
Sixteen cats with malignant tumors (10 carcinomas, 6 sarcomas) of the nasal cavity and paranasal sinuses were treated with curative intent by radiotherapy. Clinical stating was based on radiographic findings, using the tumor, node, metastasis classification system of the World Health Organization. Irradiation was done with a telecobalt-60 unit (13 cats) and an orthovoltage unit (3 cats). Fourteen cats were treated with irradiation alone, and 2 cats had incomplete surgical resections prior to radiotherapy. Treatment dose was 48 Gy (minimum tumor dose), administered by use of 4 Gy per fraction on a Monday/Wednesday/Friday basis over 4 weeks. Survival times after treatment ranged from 1 to 36 months. The 1- and 2-year overall survival rates were 44.3 and 16.6%, respectively. Histologic type and clinical stage did not have prognostic value. Most acute radiation reactions were mild and self-limiting. Chronic ocular complications were seen in 3 cats. These treatment responses compared favorably with those previously described in dogs and cats with intranasal neoplasms treated with teletherapy and provided a perspective for comparison of new treatment methods.
Théon
A P
AP
Department of Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616-8742.
Peaston
A E
AE
Madewell
B R
BR
Dungworth
D L
DL
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary; D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary; D002371:Cat Diseases / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy*; D002415:Cats; D005260:Female; D005354:Fibrosarcoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary; D008297:Male; D009296:Nasal Cavity; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary*; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary*; D011379:Prognosis; D011859:Radiography; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy / Q000662:veterinary; D015996:Survival Rate; D016896:Treatment Outcome