A cytochemical method for the identification of ischemic and necrotic myocardial fibres.
The author studied the nickel-dimethylglioxim reaction in ischemic and necrotic myocardium fibres in dogs, following ligature of the left anterior descending coronary artery. The nickel-dimethylglioxim reaction was positive in ischemic fibers, but not in necrotic ones. The cytochemical reaction, observed in ischemic fibers, was localized in the intracellular compartment and in the mitochondria.
Felszeghy
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Institute of Forensic Medicine, Semmelweis University of Medicine, Budapest, Hungary.
D000818:Animals; D001329:Autolysis; D003937:Diagnosis, Differential; D004195:Disease Models, Animal; D004285:Dogs; D004338:Drug Combinations; D005260:Female; D005554:Forensic Medicine / Q000379:methods*; D006651:Histocytochemistry / Q000379:methods*; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000378:metabolism; D009336:Necrosis; D009532:Nickel; D010091:Oximes
D004338:Drug Combinations; D010091:Oximes; C013501:dimethylglyoxime; D009532:Nickel