title: Spontaneous globoid mineralization in the cerebellum of rats.
abstract: Cerebellar globoid mineralization in two rats was examined by light and electron microscopy, and by X-ray microanalysis. The mineralization was round to oval in shape; it varied in size and was positive for the periodic acid-Schiff and von Kossa reactions. Ultrastructurally, a concentric lamellar structure was prominent in moderately electron-dense depositions. Elemental analysis revealed the presence of large amounts of calcium and phosphorus, and small amounts of zinc, potassium and aluminum.
authors.affiliation: Department of Veterinary Pathology, Faculty of Agriculture, Gifu University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yanai
authors.forename: T
authors.initials: T
authors.lastname: Masegi
authors.forename: K
authors.initials: K
authors.lastname: Ueda
authors.forename: J
authors.initials: J
authors.lastname: Manabe
authors.forename: M
authors.initials: M
authors.lastname: Teranishi
authors.forename: M
authors.initials: M
authors.lastname: Takaoka
authors.forename: N
authors.initials: N
authors.lastname: Matsunuma
authors.forename: K
authors.initials: K
authors.lastname: Fukuda
authors.forename: N
authors.initials: N
authors.lastname: Goto
mesh_terms: D000818:Animals; D002118:Calcium / Q000032:analysis; D002531:Cerebellum / Q000737:chemistry* / Q000000981:diagnostic imaging; D004577:Electron Probe Microanalysis / Q000662:veterinary; D005260:Female; D008297:Male; D008854:Microscopy, Electron / Q000662:veterinary; D008903:Minerals / Q000032:analysis*; D010758:Phosphorus / Q000032:analysis; D011859:Radiography; D051381:Rats; D011916:Rats, Inbred F344
chemical_list: D008903:Minerals; D010758:Phosphorus; D002118:Calcium