Immune recognition of polar pili from Pseudomonas aeruginosa O.
The B- and T-cell antigenic sites on type O pili from Pseudomonas aeruginosa were determined by using an antipilus antibody competition assay and PAO-immune T-cell blasts in proliferation studies. The citraconylated tryptic digest III region (residues 54 to 120) was determined to be an immunodominant site for both T and B cells on the pilin molecule.
Smart
W
W
Department of Immunology, University of Alberta, Edmonton, Canada.
Sastry
P A
PA
Paranchych
W
W
Singh
B
B
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D003429:Cross Reactions; D010861:Fimbriae, Bacterial / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011550:Pseudomonas aeruginosa / Q000276:immunology*; D011817:Rabbits; D013601:T-Lymphocytes / Q000276:immunology*