Liver transplantation for a hepatitis B-related cirrhotic patient.
A patient with chronic end-stage liver cirrhosis resulting from a hepatitis B viral infection had a successful liver transplantation performed on 1 July 1991. Preoperative serology revealed that both HBsAg and HBeAg were positive, and the anti-HBs antibody was negative. Immunoprophylaxis included active immunization, as well as injections of large doses of hepatitis B immunoglobulin (HBIG) given perioperatively to reverse the antigen status. The patient has been anti-HBs antibody positive for more than 10 months since the transplantation. The immunoprophylaxis protocol used has been effective in the prevention of hepatitis B viral reinfection.
Jeng
L B
LB
Department of Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.
Hsu
C H
CH
Wang
C S
CS
Chen
R J
RJ
Chen
S C
SC
Chen
M F
MF
Chen
T J
TJ
Chiu
C T
CT
Lin
D Y
DY
Liaw
Y F
YF
D000328:Adult; D006509:Hepatitis B / Q000150:complications* / Q000276:immunology; D006801:Humans; D007116:Immunization, Passive; D007165:Immunosuppression Therapy; D008103:Liver Cirrhosis / Q000150:complications / Q000276:immunology / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male