title: An intra-operative comparison of lumbar with thoracic epidural sufentanil for thoracotomy.
abstract: The efficacy of thoracic epidural sufentanil 50 micrograms was compared with lumbar epidural sufentanil 50 micrograms in 30 patients (n = 15 in each group) undergoing lateral thoracotomy. Sufentanil was administered epidurally after induction of anaesthesia with sufentanil 1 microgram.kg-1 and thiopentone 2-5 mg.kg-1 intravenously. Anaesthesia, nitrous oxide 66%, halothane 0.3% and sufentanil 25 micrograms intravenously were given whenever the systolic arterial blood pressure increased more than 15 mmHg above the preoperative value and heart rate exceeded 90 beat.min-1 in the absence of hypovolaemia, or when other autonomic or somatic signs were seen. Four patients in the thoracic epidural group and five in the lumbar epidural group needed supplementary sufentanil. Six patients in the thoracic epidural group and three in the lumbar epidural group each had a single hypotensive episode. Lumbar and thoracic epidural sufentanil are equally effective in contributing to intra-operative analgesia for lateral thoracotomy.
authors.affiliation: Department of Anaesthesiology, University Hospital Leiden, The Netherlands.
authors.forename: F
authors.initials: F
authors.lastname: Haak-van der Lely
authors.forename: J W
authors.initials: JW
authors.lastname: van Kleef
authors.forename: A G
authors.initials: AG
authors.lastname: Burm
authors.forename: J G
authors.initials: JG
authors.lastname: Bovill
mesh_terms: D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000771:Anesthesia, Intravenous; D005260:Female; D006801:Humans; D007022:Hypotension / Q000209:etiology; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D017409:Sufentanil / Q000008:administration & dosage*; D013874:Thiopental; D013904:Thoracic Vertebrae; D013908:Thoracotomy
chemical_list: D017409:Sufentanil; D013874:Thiopental