Cardiopulmonary effects of a combination of medetomidine and butorphanol in atropinized pigs.
Cardiopulmonary effects of a combination of medetomidine and butorphanol were evaluated in atropinized pigs. This combination unchanged the cardiac output and significantly lowered the oxygen consumption compared with base-line values. Although some statistically significant changes were recorded, both medetomidine and butorphanol did not have a marked effect on the cardiopulmonary parameters in atropinized pigs. It was indicated that the administration of the combination of medetomidine and butorphanol is relatively safe in atropinized pigs.
Sakaguchi
M
M
Department of Veterinary Surgery, Faculty of Agriculture, University of Tokyo, Japan.
Nishimura
R
R
Sasaki
N
N
Ishiguro
T
T
Tamura
H
H
Takeuchi
A
A
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D002077:Butorphanol / Q000494:pharmacology*; D002369:Castration; D004347:Drug Interactions; D006321:Heart / Q000187:drug effects / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D008168:Lung / Q000187:drug effects / Q000502:physiology*; D020926:Medetomidine; D011652:Pulmonary Circulation / Q000187:drug effects; D012129:Respiratory Function Tests; D013552:Swine; D014655:Vascular Resistance / Q000187:drug effects
D000316:Adrenergic alpha-Agonists; D006993:Hypnotics and Sedatives; D007093:Imidazoles; D001285:Atropine; D020926:Medetomidine; D002077:Butorphanol