title: Retrobulbar block fails to prevent an increase in serum cortisol concentration on emergence from anaesthesia after cataract surgery.
abstract: We have studied 30 elderly patients undergoing cataract surgery, allocated randomly to receive general anesthesia, local anaesthesia by retrobulbar block or general anaesthesia combined with retrobulbar block given after induction. Retrobulbar block alone prevented the increases in circulating cortisol and glucose values which occurred in those patients receiving general anaesthesia alone. Retrobulbar block given after induction of general anaesthesia, however, suppressed the cortisol and glucose response during surgery, but did not prevent a marked increase in cortisol concentrations during the immediate postoperative period. The results suggest a hormonal response to emergence from anaesthesia which has hitherto been masked by the stress response to surgery itself.
authors.affiliation: Department of Anaesthesia, Edgware General Hospital, Middx.
authors.forename: J P
authors.initials: JP
authors.lastname: Barker
authors.forename: P N
authors.initials: PN
authors.lastname: Robinson
authors.forename: G C
authors.initials: GC
authors.lastname: Vafidis
authors.forename: J M
authors.initials: JM
authors.lastname: Burrin
authors.forename: G M
authors.initials: GM
authors.lastname: Hall
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General; D000772:Anesthesia, Local / Q000379:methods*; D001786:Blood Glucose / Q000378:metabolism; D002387:Cataract Extraction; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D009407:Nerve Block / Q000379:methods*; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D006854:Hydrocortisone