title: Precise localization on chromosome 12 of the ATF-1 gene by fluorescence in situ hybridization.
abstract: The ATF-1 gene encodes for a transcription factor normally regulated by cAMP (Hai et al. 1989, Yoshimura et al. 1990). Recently, it has been shown to be involved in the recurrent t(12;22) translocation observed in soft tissue malignant melanoma, in a fusion gene with the EWS gene (Zucman et al. 1993). We report here on its precise localization on chromosome 12 by fluorescence in situ hybridization.
authors.affiliation: Laboratoire de Génétique des Tumeurs, INSERM CJF 9201, Institut Curie, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Desmaze
authors.forename: J
authors.initials: J
authors.lastname: Zucman
authors.forename: O
authors.initials: O
authors.lastname: Delattre
authors.forename: T
authors.initials: T
authors.lastname: Melot
authors.forename: G
authors.initials: G
authors.lastname: Thomas
authors.forename: A
authors.initials: A
authors.lastname: Aurias
mesh_terms: D051697:Activating Transcription Factor 1; D002881:Chromosomes, Human, Pair 12 / Q000737:chemistry*; D004268:DNA-Binding Proteins; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods*; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D051697:Activating Transcription Factor 1; D004268:DNA-Binding Proteins; D014157:Transcription Factors