[Inborn and induced lipidosis. Differential diagnosis].
The drugs used for the treatment of psychiatric disorders sometimes produce neurological symptoms (drug-induced lipidosis) similar to those found in subjects with genetic disorders of lipid metabolism. We report the case of a young man with Niemann-Pick disease first treated for behavioural disorders. As the family accused the Medical Department to be responsible for a disease caused by excess of medication, a detailed study of the patient's biochemical features was used to refute the complaint.
Turpin
J C
JC
Service de Neurologie, Hôpital Robert Debré, CHU, Reims.
Dubois
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D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects; D003937:Diagnosis, Differential; D006801:Humans; D007049:Iatrogenic Disease; D008064:Lipidoses / Q000139:chemically induced / Q000175:diagnosis* / Q000201:enzymology / Q000235:genetics; D008297:Male; D013108:Sphingomyelin Phosphodiesterase / Q000378:metabolism; D013109:Sphingomyelins / Q000378:metabolism
D014150:Antipsychotic Agents; D013109:Sphingomyelins; D013108:Sphingomyelin Phosphodiesterase
Lipidose innée et lipidose induite. Diagnostic différentiel.