title: Comparison of cone-mediated electroretinograms obtained before and after vincristine chemotherapy.
abstract: Vincristine has been shown to reduce the amplitude of postreceptoral electroretinographic components in the isolated arterially perfused cat eye. We examined whether a similar effect occurs in vincristine chemotherapy. In the three patients tested, cone-mediated electroretinograms recorded before and after vincristine chemotherapy were not different. This observation is likely to reflect the lower doses of vincristine used therapeutically.
authors.affiliation: Hines Veterans Affairs Hospital, Illinois.
authors.forename: W
authors.initials: W
authors.lastname: Yee
authors.forename: N
authors.initials: N
authors.lastname: Bhoopalam
authors.forename: N S
authors.initials: NS
authors.lastname: Peachey
mesh_terms: D000368:Aged; D004596:Electroretinography / Q000187:drug effects*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000502:physiology; D017949:Retinal Cone Photoreceptor Cells / Q000187:drug effects / Q000502:physiology* / Q000503:physiopathology; D013945:Thymoma / Q000188:drug therapy; D013953:Thymus Neoplasms / Q000188:drug therapy; D014750:Vincristine / Q000627:therapeutic use*
chemical_list: D014750:Vincristine