title: [Pelvic vein thrombosis in protein C deficiency after infectious mononucleosis].
abstract: Subsequent to an infectious mononucleosis a 15 year old girl developed a thrombosis of the iliaca vein. Laboratory evaluation revealed a heterozygous form of protein C deficiency. An infusion with r-tPA (= recombinant tissue plasminogen activator) at a rate of 0.02 mg/kg BW/h over 96 hours failed to reopen the vessel. After intermittent heparin therapy longterm treatment with coumarin began. Three months later the iliaca vein was partially recanalised.
authors.affiliation: Kinderklinik und Kinderpoliklinik, Technische Universität München.
authors.forename: U
authors.initials: U
authors.lastname: Knees
authors.forename: E
authors.initials: E
authors.lastname: Macdonald
authors.forename: H
authors.initials: H
authors.lastname: Stiegler
authors.forename: A
authors.initials: A
authors.lastname: Ohly
authors.forename: B F
authors.initials: BF
authors.lastname: Pontz
mesh_terms: D000293:Adolescent; D003131:Combined Modality Therapy; D003374:Coumarins / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007084:Iliac Vein / Q000000981:diagnostic imaging; D007244:Infectious Mononucleosis / Q000097:blood*; D008134:Long-Term Care; D020151:Protein C Deficiency; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000097:blood* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000235:genetics; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014463:Ultrasonography
chemical_list: D003374:Coumarins; D006493:Heparin; C030123:coumarin; D010959:Tissue Plasminogen Activator
vernacular_title: Beckenvenenthrombose bei Protein-C-Mangel nach infektiöser Mononukleose.