Reconstitution of transmitter secretion.
Molecular mechanisms involved in the various stages of transmitter secretion have been studied by perturbing the composition of secretory cells using pharmacological and biochemical agents. An emerging approach is to reconstitute individual steps or the entire sequence of secretion mechanisms in non-secretory cells by loading the cell with presynaptic components or their mRNAs.
Alder
J
J
Department of Biological Sciences, Columbia University, New York, NY 10027.
Poo
M M
MM
D000818:Animals; D006801:Humans; D018377:Neurotransmitter Agents / Q000378:metabolism*; D013572:Synaptic Vesicles / Q000378:metabolism / Q000502:physiology
D018377:Neurotransmitter Agents