[Chronic beta-stimulant therapy: a possible etiopathogenic factor for hypertrophic cardiomyopathy].
We herein report the case of a 37-year-old woman, referred to our Unit because of atypical chest pain, negative T waves in leads V1-6 and medio-apical hypertrophic cardiomyopathy, diagnosed by two-dimensional echocardiography. The patient suffered from status asthmaticus and consequently had been treated for a twenty year period with beta-adrenoceptor stimulating agents, corticosteroids, theophylline. No coronary stenosis was revealed by coronary angiography. The results of electrocardiographic and two-dimensional echocardiographic investigations, performed after interruption of beta-stimulations, showed a regression of hypertrophic cardiomyopathy. We suggest that hypertrophic cardiomyopathy could be induced by beta-adrenergic stimulation.
Speca
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G
U.T.I.C., Ospedale Civile, Teramo.
Core
A
A
Pardi
L
L
D000318:Adrenergic beta-Agonists / Q000009:adverse effects*; D000328:Adult; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D002312:Cardiomyopathy, Hypertrophic / Q000139:chemically induced* / Q000175:diagnosis; D004359:Drug Therapy, Combination; D004452:Echocardiography / Q000187:drug effects; D004562:Electrocardiography / Q000187:drug effects; D004630:Emergencies; D005260:Female; D006801:Humans
D000318:Adrenergic beta-Agonists
Terapia cronica con beta-stimolanti: un possibile fattore etiopatogenetico per la cardiomiopatia ipertrofica.