title: Pupil cycle time and human immunodeficiency virus (HIV) infection.
abstract: The pupil cycle time (PCT) was measured in 22 HIV-positive patients and 22 age/sex-matched controls. Of the HIV-positive group, 13 (59%) met the Centre for Disease Control classification of acquired immunodeficiency syndrome (AIDS) defining illness. There was a highly statistically significant difference in the PCT between the HIV-infected group and the control group (p < 0.0001, Student's t-test). Within the HIV-infected group there was no statistically significant difference in the PCT between those patients with full-blown AIDS and the others. This study suggests that HIV infection may be associated with subclinical ocular autonomic dysfunction even in the earlier stages of HIV infection.
authors.affiliation: Princess Alexandra Eye Pavilion, Edinburgh, UK.
authors.forename: H
authors.initials: H
authors.lastname: Maclean
authors.forename: B
authors.initials: B
authors.lastname: Dhillon
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology; D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000503:physiopathology; D005260:Female; D015658:HIV Infections / Q000503:physiopathology*; D006801:Humans; D008297:Male; D012025:Reflex, Pupillary / Q000502:physiology*; D013997:Time Factors