Gd-DTPA enhanced MRI of reactive hematopoietic regions in marrow.
OBJECTIVE
The purpose of this report was to study the contrast enhancement of reactive hematopoietic regions in bone marrow on Gd-diethylenetriamine pentaacetic acid (DTPA) enhanced MRI.


METHODS
We compared the contrast enhancement of reactive hematopoietic regions in the marrow of patients with aplastic anemia and drug-induced pancytopenia and that of normal bone marrow on Gd-DTPA enhanced MRI.


RESULTS
The reactive hematopoietic marrow observed in aplastic anemia of moderate grade and drug-induced pancytopenia markedly enhanced after Gd-DTPA administration; normoplastic marrow showed no enhancement.


CONCLUSIONS
Gd-DTPA enhanced MRI was useful in detecting the reactive hematopoietic regions in bone marrow.
Amano
Y
Y
Department of Radiology, Nippon Medical School, Tokyo, Japan.
Hayashi
H
H
Kumazaki
T
T
D000328:Adult; D000741:Anemia, Aplastic / Q000175:diagnosis / Q000473:pathology; D001853:Bone Marrow / Q000033:anatomy & histology* / Q000502:physiology; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006410:Hematopoiesis / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010198:Pancytopenia / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D004369:Pentetic Acid / Q000031:analogs & derivatives*
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA