Crystallographic determination of thrombin complexes with small synthetic inhibitors as a starting point for the receptor-based design of antithrombotics.
Bauer
M
M
Max-Planck-Institut für Biochemie, Martinsried, Germany.
Brandstetter
H
H
Turk
D
D
Stürzebecher
J
J
Bode
W
W
D000595:Amino Acid Sequence; D000991:Antithrombins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D015195:Drug Design; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D018179:Receptors, Thrombin / Q000378:metabolism*; D013917:Thrombin / Q000737:chemistry*
D000991:Antithrombins; D018179:Receptors, Thrombin; D013917:Thrombin