title: Clinicopathologic study of Gore-Tex patch graft in corneoscleral surgery.
abstract: Three patients with corneal or scleral defects were treated with Gore-Tex grafting, including one case of corneal ulcer, one case of Mooren's ulcer, and one case of necrotizing scleritis. These eyes remained inflamed after Gore-Tex grafting. The interval between grafting and removal ranged from 2 months to 1 year. Pathologically, none of these grafts showed evident epithelial or fibrous tissue ingrowth of the Gore-Tex graft. Fungal inhabitation was noted in one graft, and fungal endophthalmitis developed 5 months after graft removal and penetrating keratoplasty. Although Gore-Tex offers some advantages, it has disadvantages when it is used without adequate conjunctival covering, including poor epithelialization, poor adhesion between graft and surrounding tissue, and potential infectious route.
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, Taipei, Republic of China.
authors.forename: W J
authors.initials: WJ
authors.lastname: Huang
authors.forename: F R
authors.initials: FR
authors.lastname: Hu
authors.forename: S W
authors.initials: SW
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D002448:Cell Adhesion; D003315:Cornea / Q000473:pathology* / Q000601:surgery; D003320:Corneal Ulcer / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D019736:Prostheses and Implants; D012590:Sclera / Q000473:pathology* / Q000601:surgery; D015423:Scleritis / Q000473:pathology / Q000601:surgery*
chemical_list: D011138:Polytetrafluoroethylene