Infections in systemic lupus erythematosus.
A prospective study was carried out on the occurrence of infections in 28 hospitalised systemic lupus erythematosus (SLE) patients. In 38 episodes of infections, 23 were bacterial (60.5%), 4 were viral (10.6%) and culture negative infections were present in 10 (26.3%). The most common isolated organisms were Staphylococcus aureus (30.4%), Salmonella species (21.7%), Pseudomonas species (13.0%), and Klebsiella species (13.0%). The care rate was 94.7%. Death occurred in 2 patients. Lupus activity, impaired renal function, and cytotoxic therapy did not predispose to infection.
Oh
H M
HM
Communicable Disease Centre, Singapore.
Chng
H H
HH
Boey
M L
ML
Feng
P H
PH
D000293:Adolescent; D000328:Adult; D001424:Bacterial Infections / Q000150:complications / Q000453:epidemiology*; D003165:Complement System Proteins / Q000172:deficiency; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010343:Patient Admission / Q000706:statistics & numerical data; D011241:Prednisone / Q000627:therapeutic use; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012307:Risk Factors; D012846:Singapore / Q000453:epidemiology; D017192:Skin Diseases, Bacterial / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology
D007136:Immunoglobulins; D003165:Complement System Proteins; D003404:Creatinine; D011241:Prednisone