title: The association between 'faint-positive' amniotic fluid acetylcholinesterase and fetal malformations.
abstract: The finding of a 'faint-positive' acetylcholinesterase band in amniotic fluid samples of women at 15 weeks' gestation or above is associated with an increased risk of fetal abnormalities, most commonly gastroschisis. This finding warrants a targeted sonographic evaluation, in order to rule out significant fetal malformations.
authors.affiliation: Department of Obstetrics and Gynecology and Reproductive Sciences, University of California, San Francisco.
authors.forename: Y
authors.initials: Y
authors.lastname: Sadovsky
authors.forename: M L
authors.initials: ML
authors.lastname: Robbin
authors.forename: B F
authors.initials: BF
authors.lastname: Crandall
authors.forename: R A
authors.initials: RA
authors.lastname: Filly
authors.forename: M S
authors.initials: MS
authors.lastname: Golbus
mesh_terms: D000110:Acetylcholinesterase / Q000032:analysis*; D000653:Amniotic Fluid / Q000201:enzymology*; D000013:Congenital Abnormalities / Q000175:diagnosis*; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000110:Acetylcholinesterase