title: A new cytogenetic finding in an epithelioid sarcoma, t(8;22)(q22;q11).
abstract: We report a new translocation t(8;22)(q22;q11) in a single case of epithelioid sarcoma. The band involved in chromosome 22 is the same found in 70-80% of the case of Ewing's sarcoma/peripheral neuroepithelioma (PNET) with cytogenetic characterization. The histologic characteristics of this tumor were typical for epithelioid sarcoma. Immunohistochemical stains were also entirely consistent with this diagnosis, including non-reactivity with P30/32MIC2, a specific marker for Ewing's sarcoma/primitive neuroepithelioma.
authors.affiliation: Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: J C
authors.initials: JC
authors.lastname: Cordoba
authors.forename: D M
authors.initials: DM
authors.lastname: Parham
authors.forename: W H
authors.initials: WH
authors.lastname: Meyer
authors.forename: E C
authors.initials: EC
authors.lastname: Douglass
mesh_terms: D002648:Child; D002892:Chromosomes, Human, Pair 22; D002898:Chromosomes, Human, Pair 8; D005542:Forearm; D006801:Humans; D008297:Male; D012509:Sarcoma / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic