title: [Effect of chitosan sulfates on lipoprotein lipase activity].
abstract: Effect of commercially available preparations of chitosan sulfate on the total lipolytic activity was studied in rabbit blood. Chitosan sulfates, administered per os or intravenously, proved to be highly effective activators of lipolytic enzymes. The most distinct efficiency exhibited preparations with molecular mass of 60-120 x 10(3) and the rate of sulfation 1.20-1.35. After administration of the chitosan sulfates into hyperlipidemic rats a decrease in blood plasma VLDL and increased HDL content were observed.
authors.forename: M A
authors.initials: MA
authors.lastname: Solov'eva
authors.forename: I N
authors.initials: IN
authors.lastname: Gorbacheva
authors.forename: G A
authors.initials: GA
authors.lastname: Vikhoreva
authors.forename: L S
authors.initials: LS
authors.lastname: Gal'braĭkh
authors.forename: V E
authors.initials: VE
authors.lastname: Ryzhenkov
mesh_terms: D000818:Animals; D002686:Chitin / Q000031:analogs & derivatives* / Q000494:pharmacology; D048271:Chitosan; D004789:Enzyme Activation; D008071:Lipoprotein Lipase / Q000097:blood / Q000187:drug effects* / Q000378:metabolism; D008075:Lipoproteins, HDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D011817:Rabbits
chemical_list: D008075:Lipoproteins, HDL; D008079:Lipoproteins, VLDL; D002686:Chitin; D048271:Chitosan; D008071:Lipoprotein Lipase
vernacular_title: Vliianie sul'fatov khitozana na aktivnost' lipoproteinlipazy.