[Effect of liposomes on lipid peroxidation in the heart and liver in crush syndrome].
The increased lipid peroxidation has been determined to be one of general mechanisms of disturbance in the functional state of the heart and liver fraction cells, regularities of inter-system disturbance in metabolic activity under the crush syndrome have been revealed. Administration of lecithin liposomes results in the decreased POL levels, increased antioxidant capacity of the organism. That permits recommending to include liposomes into complex therapeutics of the crush syndrome as detoxicating, antiinflammatory and antihypoxic drug.
El'skiĭ
V N
VN
Stefanov
A V
AV
Mareeva
T E
TE
Kolesnikova
S V
SV
Skobeleva
E I
EI
Kas'ianova
E V
EV
D000818:Animals; D003444:Crush Syndrome / Q000188:drug therapy* / Q000378:metabolism; D005609:Free Radicals; D006321:Heart / Q000187:drug effects*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008081:Liposomes / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D010713:Phosphatidylcholines / Q000494:pharmacology*; D051381:Rats
D005609:Free Radicals; D008081:Liposomes; D010713:Phosphatidylcholines
Vliianie liposom na perekisnoe okislenie lipidov v serdtse i pecheni pri sindrome dlitel'nogo razdavlivaniia.