[The genetic aspects of neurogenic syncopes].
The authors specified the prevalence of syncopal states in the representative sample of 2309 schoolchildren from the city of Kazan, as well as hereditary factors in the genesis of neurogenic syncopes basing on the clinico-genealogical analysis of 115 families. 91.4% of the syncopal conditions were considered to be neurogenic syncopes (populational frequency is 6.41%) and family disease close by relevant characteristics to multifactorial illnesses with rather high (73.5%) proportion of the genetic factors. When the parents remarried by type patient-to-patient, the segregation rate (0.43) of neurogenic syncopes is close to the expected (0.50) though this does not rule out a dominant model of monogenic affection.
Ismagilov
M F
MF
Gaĭnetdinova
D D
DD
D000328:Adult; D002648:Child; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009422:Nervous System Diseases / Q000150:complications / Q000453:epidemiology / Q000235:genetics*; D010375:Pedigree; D012426:Russia / Q000453:epidemiology; D012737:Sex Factors; D013575:Syncope / Q000453:epidemiology / Q000209:etiology / Q000235:genetics*; D014505:Urban Population / Q000706:statistics & numerical data
Geneticheskie aspekty nevrogennykh obmorokov.