title: Electron-beam therapy in scleredema adultorum with associated monoclonal hypergammaglobulinaemia.
abstract: We report a case of scleredema adultorum (Buschke's disease) associated with an IgA kappa monoclonal hypergammaglobulinaemia. A significant improvement in the skin was obtained with electron-beam therapy. Scleredema would appear to be linked to monoclonal hypergammaglobulinaemia, but the relationship between the skin disorder and the immunoglobulin abnormality remains to be elucidated.
authors.affiliation: Department of Dermatology, CHU la Timone, Marseille, France.
authors.forename: C
authors.initials: C
authors.lastname: Angeli-Besson
authors.forename: M C
authors.initials: MC
authors.lastname: Koeppel
authors.forename: P
authors.initials: P
authors.lastname: Jacquet
authors.forename: L
authors.initials: L
authors.lastname: Andrac
authors.forename: J
authors.initials: J
authors.lastname: Sayag
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004583:Electrons; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains; D008297:Male; D008875:Middle Aged; D011882:Radiotherapy, High-Energy; D012592:Scleredema Adultorum / Q000150:complications / Q000473:pathology / Q000532:radiotherapy*
chemical_list: D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains