title: Cardiopulmonary bypass with Nikkiso and BioMedicus centrifugal pumps.
abstract: In our department, a new compact and atraumatic centrifugal pump, Nikkiso, was developed as a second-generation cardiopulmonary bypass pump. To assess and confirm the function and controllability of this pump, comparative studies of cardiopulmonary bypass with Nikkiso and BioMedicus centrifugal pumps were performed using calves. Both pumps provided pump flows of 60-70 ml/kg/min without incidence. The hemodynamics of both groups were stable and within the normal range, and no leakage or thrombus formations were observed in either pump. All hematology and biochemistry data showed no significant differences between the two groups. Plasma free hemoglobin values of the Nikkiso pump tended to be lower than those of the BioMedicus pump. The Nikkiso pump was easy to handle because of its smaller size, and air removal was easily performed because of its low priming volume. The Nikkiso pump demonstrated easy manipulation and good controllability. This compact, atraumatic centrifugal pump meets the requirements for a second-generation cardiopulmonary bypass pump.
authors.affiliation: Department of Surgery, Baylor College of Medicine, Houston, Texas 77030.
authors.forename: Y
authors.initials: Y
authors.lastname: Orime
authors.forename: S
authors.initials: S
authors.lastname: Takatani
authors.forename: T
authors.initials: T
authors.lastname: Sasaki
authors.forename: T
authors.initials: T
authors.lastname: Aizawa
authors.forename: Y
authors.initials: Y
authors.lastname: Ohara
authors.forename: K
authors.initials: K
authors.lastname: Naito
authors.forename: J
authors.initials: J
authors.lastname: Glueck
authors.forename: G P
authors.initials: GP
authors.lastname: Noon
authors.forename: Y
authors.initials: Y
authors.lastname: Nosé
authors.forename: M E
authors.initials: ME
authors.lastname: DeBakey
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis; D002315:Cardiopulmonary Bypass / Q000295:instrumentation*; D002417:Cattle; D005260:Female; D006400:Hematocrit; D006439:Hemodynamics; D006454:Hemoglobins / Q000032:analysis
chemical_list: D006454:Hemoglobins