title: Successful management of viable cervical pregnancy by local injection of methotrexate guided by transvaginal ultrasonography.
abstract: We evaluated the feasibility of transvaginal methotrexate injection of viable cervical pregnancies to avoid complications of the "classic" surgical procedures in use and to preserve future fertility. Five viable cervical pregnancies, at 6 to 8 weeks, were treated. In three patients a spring-loaded automated puncture device and in two a manually operated simple needle guide mated to and guided by a transvaginal ultrasonography probe were used with 21-gauge needles. The puncture and injection treatment was successful and without complications in all five cases presented. This procedure may become a useful alternative to other, more radical or complex surgical approaches.
authors.affiliation: Department of Obstetrics and Gynecology, Sloane Hospital for Women, Columbia Presbyterian Medical Center, New York, NY 10032.
authors.forename: I E
authors.initials: IE
authors.lastname: Timor-Tritsch
authors.forename: A
authors.initials: A
authors.lastname: Monteagudo
authors.forename: E O
authors.initials: EO
authors.lastname: Mandeville
authors.forename: D B
authors.initials: DB
authors.lastname: Peisner
authors.forename: G P
authors.initials: GP
authors.lastname: Anaya
authors.forename: E C
authors.initials: EC
authors.lastname: Pirrone
mesh_terms: D002584:Cervix Uteri / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage* / Q000627:therapeutic use; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011677:Punctures; D014463:Ultrasonography; D014621:Vagina
chemical_list: D008727:Methotrexate