[Angiotensin-converting enzyme inhibitors and pregnancy. Apropos of 2 cases].
Angiotensin converting enzyme inhibitors do not have any teratogenic effect in man but their use during pregnancy has led to cases of hypotension and subsequent severe renal failure in the newborn. The authors report two cases, one involving a twin pregnancy which illustrate the variability of the foetal involvement. It is emphasized that the side effects of angiotensin converting enzyme inhibitors are not only reversible but also are not constantly found.
Lenoir
S
S
Unité INSERM CJF 8908, Hôpital La Grave, Toulouse.
Rhabbour
M
M
Grandjean
B
B
Fournié
A
A
Rolland
M
M
D000328:Adult; D004200:Diseases in Twins; D004656:Enalapril / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced / Q000151:congenital; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities; D007676:Kidney Failure, Chronic / Q000139:chemically induced* / Q000151:congenital*; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000139:chemically induced; D014427:Twins
D004656:Enalapril
Les inhibiteurs de l'enzyme de conversion de l'angiotensine et la grossesse. A propos de deux observations.