[Acquired hemophilia and rheumatoid arthritis. Value of intravenous immunoglobulins].
The authors report an exceedingly rare complication of rheumatoid arthritis, i.e. acquired hemophilia due to anti-factor VIII autoantibody production. Treatment with intravenous immune globulin ensured control of hemorrhagic manifestations by inducing a transient rise in factor VIII level.
Struillou
L
L
Service de Médecine Interne, Hôtel-Dieu, Nantes.
Fiks-Sigaud
M
M
Barrier
J H
JH
Blat
E
E
Magadur-Joly
G
G
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000276:immunology; D001323:Autoantibodies / Q000302:isolation & purification; D005169:Factor VIII / Q000276:immunology; D005260:Female; D006467:Hemophilia A / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*
D001323:Autoantibodies; D016756:Immunoglobulins, Intravenous; D005169:Factor VIII
Hemophilie acquise et polyarthrite rhumatoïde. Intérêt des immunoglobulines intra-veineuses.