The human locus coeruleus and anxiogenesis.
Electrical stimulation of locus coeruleus (LC), via permanently implanted electrodes with confirmed localization and effectiveness, did not elicit any subjective or behavioral manifestations of anxiety. This is evidence against the hypothesis that LC is a mediator of anxiogenesis in man.
Libet
B
B
Department of Physiology, University of California at San Francisco 94143-0444.
Gleason
C A
CA
D000328:Adult; D001007:Anxiety / Q000503:physiopathology*; D002648:Child; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D005260:Female; D006801:Humans; D008125:Locus Coeruleus / Q000503:physiopathology*