title: Multiple disorder diagnosis with adaptive competitive neural networks.
abstract: Backpropagation neural networks have repeatedly been used for diagnostic problem-solving, but have not been demonstrated to work well when multiple disorders are present. We hypothesized that letting nodes in a backpropagation neural network compete to be part of a diagnostic solution would produce better performance than the use of existing backpropagation methods. To test this hypothesis, we derived an error backpropagation learning rule that can be used with competitive units (competitive backpropagation). Artificial neural networks were then trained using both this new learning rule and standard error backpropagation on a specific medical diagnosis problem: identification of the location of damage in the brain given a set of examination findings. Training samples included solely 'prototypical' cases where a single location of damage is present. The trained networks were then tested with atypical cases where the manifestations of more than one disorder were present or only a single manifestation was present. Networks employing competition among units were found to perform qualitatively better with these multiple-disorder cases than standard networks and also to perform better on single-manifestation cases. The reasons for this are explained. The competitive backpropagation learning rule described here provides a promising new tool for adaptive diagnostic problem-solving.
authors.affiliation: Department of Computer Science and Engineering, Pohang Institute of Science and Technology, Kyungbook, South Korea.
authors.forename: S
authors.initials: S
authors.lastname: Cho
authors.forename: J A
authors.initials: JA
authors.lastname: Reggia
mesh_terms: D003936:Diagnosis, Computer-Assisted; D006801:Humans; D008433:Mathematics; D016571:Neural Networks, Computer