title: Surgery in patients with congenital coagulation disorders.
abstract: BACKGROUND
  Surgery is occasionally necessary in patients with congenital coagulation disorders. Major surgery for patients with haemophilia was not being done in India until recently. This paper reports the experience of a single referral centre.
  
  
  METHODS
  The data of 52 patients who were operated upon were collected from the hospital records retrospectively between 1984 and 1986 and prospectively thereafter. They included the surgical procedure performed, replacement therapy used and complications encountered.
  
  
  RESULTS
  Fifty-nine procedures were performed of which 26 were major, 30 minor and 3 were diagnostic angiograms. Blood components produced in the hospital blood bank were commonly used for replacement and primary haemostasis was achieved in all patients. Delayed bleeding due to inadequate factor levels occurred in 12 procedures and was controlled by increasing the factor replacement. One patient died of suspected acute myocardial ischaemia.
  
  
  CONCLUSIONS
  In India surgical procedures can be safely performed in patients with congenital coagulation disorders.
authors.affiliation: Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: V
authors.initials: V
authors.lastname: Bhushan
authors.forename: M
authors.initials: M
authors.lastname: Chandy
authors.forename: U
authors.initials: U
authors.lastname: Khanduri
authors.forename: D
authors.initials: D
authors.lastname: Dennison
authors.forename: A
authors.initials: A
authors.lastname: Srivastava
authors.forename: S
authors.initials: S
authors.lastname: Apte
mesh_terms: D000293:Adolescent; D000328:Adult; D001778:Blood Coagulation Disorders / Q000151:congenital*; D016913:Blood Component Transfusion; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D013514:Surgical Procedures, Operative