title: [Current perspectives in molecular virology].
abstract: For reproduction viruses depend on the metabolism of higher organisms that use a variety of different antiviral mechanisms for defense. Insights into virus-host cell interactions and in the strategies viruses employ to produce progeny virions were possible by sophisticated methods of modern virology. Knowing about the molecular mechanisms during infection and replication we have been able to counteract viral attacks on the molecular level by rationally designed vaccines. On the other hand these viruses can be used as molecular vector tools for treatment of e.g. genetically determined diseases. On the basis of new molecular-biological methods the sensitivity of detection of infectious agents and diagnosis of diseases could be drastically improved.
authors.affiliation: Institut für Medizinische Mikrobiologie und Hygiene, Universität Regensburg.
authors.forename: F
authors.initials: F
authors.lastname: Schwarzmann
authors.forename: R
authors.initials: R
authors.lastname: Wagner
authors.forename: J
authors.initials: J
authors.lastname: Mayer
authors.forename: U
authors.initials: U
authors.lastname: Reischl
authors.forename: H
authors.initials: H
authors.lastname: Wolf
mesh_terms: D015967:Gene Expression Regulation, Viral; D005822:Genetic Vectors; D006801:Humans; D007111:Immunity, Cellular; D009857:Oncogenes; D014764:Viral Proteins / Q000502:physiology; D014765:Viral Vaccines; D014777:Virus Diseases / Q000628:therapy; D014779:Virus Replication; D014780:Viruses / Q000276:immunology* / Q000472:pathogenicity*
chemical_list: D014764:Viral Proteins; D014765:Viral Vaccines
vernacular_title: Aktuelle Perspektiven in der molekularen Virologie.