Early recognition of atypical Francisella tularensis strains lacking a cysteine requirement.
Seven cultures referred to in our laboratories as unidentified gram-negative bacilli or Haemophilus species were identified as atypical strains of Francisella tularensis lacking a requirement for cysteine or enriched medium for growth. The use of cellular fatty acid composition analysis facilitated early recognition of this pathogen and prompt implementation of appropriate biosafety measures.
Bernard
K
K
National Laboratory for Bacteriology, Laboratory Centre for Disease Control, Ottawa, Ontario, Canada.
Tessier
S
S
Winstanley
J
J
Chang
D
D
Borczyk
A
A
D003264:Containment of Biohazards; D003470:Culture Media; D003545:Cysteine; D005227:Fatty Acids / Q000737:chemistry; D005604:Francisella tularensis / Q000737:chemistry / Q000254:growth & development / Q000302:isolation & purification*; D006801:Humans; D017056:Medical Laboratory Personnel; D009784:Occupational Diseases / Q000517:prevention & control; D014406:Tularemia / Q000175:diagnosis / Q000517:prevention & control; D014774:Virulence
D003470:Culture Media; D005227:Fatty Acids; D003545:Cysteine