title: [Lipoxygenase inhibitors. 3. Synthesis of tetrahydrobenzazepinone phenylhydrazones].
abstract: Tetrahydro-2H-benz[b]azepin-2-ones as starting substances are synthesized by Beckmann rearrangement of Schmidt reaction. The tetrahydrobenzazepinones are transformed into the thiones, thiolactim ethers and phenylhydrazones. The compounds are tested as inhibitors of soja lipoxygenase.
authors.affiliation: Institut für Pharmazeutische Chemie, Martin-Luther-Universität Halle-Wittenberg.
authors.forename: A
authors.initials: A
authors.lastname: Büge
authors.forename: C
authors.initials: C
authors.lastname: Locke
authors.forename: T
authors.initials: T
authors.lastname: Köhler
authors.forename: P
authors.initials: P
authors.lastname: Nuhn
mesh_terms: D001381:Azepines / Q000138:chemical synthesis* / Q000494:pharmacology; D016859:Lipoxygenase Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D010659:Phenylhydrazines / Q000138:chemical synthesis* / Q000494:pharmacology; D013025:Glycine max / Q000201:enzymology
chemical_list: D001381:Azepines; D016859:Lipoxygenase Inhibitors; D010659:Phenylhydrazines
vernacular_title: Lipoxygenase-Inhibitoren, 3. Mitt.: Synthese von Tetrahydrobenzazepinon-phenylhydrazonen.