title: Targeted gene replacement.
authors.forename: M R
authors.initials: MR
authors.lastname: Capecchi
mesh_terms: D000818:Animals; D004274:DNA, Recombinant; D005786:Gene Expression Regulation; D005818:Genetic Engineering / Q000379:methods*; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics*; D009154:Mutation
chemical_list: D004274:DNA, Recombinant