title: Inversion (14)(q11q32) in childhood T-cell acute lymphoblastic leukemia.
abstract: Inversion (14)(q11q32) is a common cytogenetic aberration in T-cell chronic lymphoid malignancies but is rare in T-cell acute lymphoblastic leukemia (T-ALL). We describe two cases of childhood T-ALL in which inv(14)(q11q32) was present concomitantly with other karyotypic aberrations typical of T-ALL. The possible significance of inv(14) in these cases is also discussed.
authors.affiliation: University Department of Pathology, Queen Mary Hospital, Hong Kong.
authors.forename: Y L
authors.initials: YL
authors.lastname: Kwong
authors.forename: M K
authors.initials: MK
authors.lastname: Shing
authors.forename: T M
authors.initials: TM
authors.lastname: Wan
authors.forename: P M
authors.initials: PM
authors.lastname: Yuen
authors.forename: A Y
authors.initials: AY
authors.lastname: Chan
authors.forename: K F
authors.initials: KF
authors.lastname: Wong
authors.forename: L C
authors.initials: LC
authors.lastname: Chan
mesh_terms: D002648:Child; D002675:Child, Preschool; D007446:Chromosome Inversion; D002883:Chromosomes, Human, Pair 14; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000235:genetics* / Q000276:immunology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000276:immunology