title: Osteoarticular allografts for reconstruction after resection of a musculoskeletal tumor in the proximal end of the tibia.
abstract: An osteoarticular allograft was used to reconstruct a skeletal deficiency in sixteen patients after resection of a tumor in the proximal end of the tibia. The status of each allograft and the condition of each involved limb were evaluated an average of nine years (range, six to fourteen years) postoperatively. The status of the allograft was evaluated according to the survival of the allograft and the occurrence of complications. Of the original sixteen allografts, seven were removed: six, between two and five years after the reconstruction and one, seven years after the reconstruction. A second reconstruction with use of an allograft was performed in five of the seven patients. Fifteen complications occurred in association with eleven of the original sixteen allografts. These included fracture of the allograft (five patients), subchondral collapse (five patients), infection (two patients), non-union (two patients), and instability of the joint (one patient). At the latest follow-up examination, nine patients had retained the original allograft, five had had a second allograft procedure, and two had had an above-the-knee amputation. The most recent result was rated excellent or good in eleven patients and fair or a failure in five, with use of the system of Mankin et al. It was rated good or excellent in nine patients and fair, poor, or a failure in six, and it was not rated in one patient who had died, according to the system of the Musculoskeletal Tumor Society.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Massachusetts General Hospital, Boston 02114.
authors.forename: D R
authors.initials: DR
authors.lastname: Clohisy
authors.forename: H J
authors.initials: HJ
authors.lastname: Mankin
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D002358:Cartilage, Articular / Q000637:transplantation*; D005260:Female; D006085:Graft Survival; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications / Q000209:etiology; D012086:Reoperation; D013977:Tibia / Q000601:surgery* / Q000637:transplantation*; D014184:Transplantation, Homologous