title: The use of e-PTFE barrier membranes for bone promotion around titanium implants placed into extraction sockets: a prospective multicenter study.
abstract: This multicenter study was conducted to determine the predictability for implants placed into immediate extraction sockets and augmented with e-PTFE barrier membranes. Forty-nine implants were placed in immediate extraction sockets. Initial and final defect measurements and the number of threads exposed were compared. Patients were followed up to 1 year after implant loading. Three implants were lost at the abutment connection surgery. The 1-year survival rate was 93.9%. Twenty barrier membranes became exposed and were removed prior to stage 2 surgery, while the remaining barriers were removed at abutment connection. The average defect bone formation for membrane-retained sites was 4.8 mm, while the average bone formation for sites in which the membranes were prematurely removed was 4.0 mm (P < .0001). At stage 2 surgery there was an average of 0.6 threads exposed (P < .001) for the membrane-retained sites and 2.6 threads for the early removal sites (NS). Forty-five pairs of nonstandardized radiographs were evaluated for bone loss after implant loading (average 7.5 months). The mesiodistal bone loss averaged 0.72 mm. Within the limits of this study, e-PTFE membranes will promote clinically and statistically significant amounts of bone around immediately placed implants. Retention of e-PTFE barriers until stage 2 surgery improves the amount of bone promoted around the implants.
authors.affiliation: University of Southern California School of Dentistry, Los Angeles.
authors.forename: W
authors.initials: W
authors.lastname: Becker
authors.forename: C
authors.initials: C
authors.lastname: Dahlin
authors.forename: B E
authors.initials: BE
authors.lastname: Becker
authors.forename: U
authors.initials: U
authors.lastname: Lekholm
authors.forename: D
authors.initials: D
authors.lastname: van Steenberghe
authors.forename: K
authors.initials: K
authors.lastname: Higuchi
authors.forename: C
authors.initials: C
authors.lastname: Kultje
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016301:Alveolar Bone Loss / Q000503:physiopathology; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology*; D011138:Polytetrafluoroethylene; D011379:Prognosis; D011446:Prospective Studies; D013524:Surgical Flaps; D014025:Titanium; D014081:Tooth Extraction
chemical_list: D015921:Dental Implants; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D014025:Titanium