[Tissue destruction as a mechanism initiating an external pathway of hemostasis].
Human and bovine brain tissues were used as a model to study phasic pattern and dynamic properties of lipid and protein components of damaged biological membranes as well as the relationships of this process with initiation of hemostasis external pathway. It was established that thromboplastic reaction is initiated by factor VII contact with the surface of apoprotein III-containing membrane. Enhanced mobility of borderline lipids correlated with thromboplastic activation of the membrane. The study made use of 1H, 31P-NMR and the test system specifically sensitive to apoprotein III.
Baĭkeev
R F
RF
Azancheev
N M
NM
Bubiakin
A N
AN
D000818:Animals; D002417:Cattle; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D008566:Membranes / Q000473:pathology
Destruktsiia tkaneĭ kak mekhanizm initsiirovaniia vneshnego puti gemostaza.