title: [The myocardial blood supply in chronic alcoholism patients studied by myocardial scintigraphy with 201Tl].
abstract: To study myocardial perfusion, 201Tl myocardial scintigraphy was used to examine 25 patients with chronic alcoholism and alcoholic damage to the heart. 201Tl myocardial scintigraphy was performed at rest and repeatedly 3-7 days later by using the bicycle ergometer exercise test. The total 201Tl uptake at rest was 2.3 +/- 0.2%. The resting scintigrams of the patients showed a profound irregularity of 201Tl distribution and a diffuse decrease in its washout. The increment of 201Tl uptake in response to exercise was 20.6%. Exercise scintigrams displayed steady perfusion defects mainly of anteroseptal site. There was an improvement of tracer washout in the exercise test as compared at rest. Thus, 201Tl myocardial scintigraphy allows perfusion disturbances to be detected in patients with alcoholic damage to the heart. Myocardial scintigraphy performed at the peak of exercise records a decreased increment of 201Tl extraction, suggesting a lower perfusion reserve in patients with alcoholic heart damage.
authors.forename: L E
authors.initials: LE
authors.lastname: Samoĭlenko
authors.forename: F S
authors.initials: FS
authors.lastname: Esshchanova
authors.forename: A G
authors.initials: AG
authors.lastname: Gorgaslidze
authors.forename: V B
authors.initials: VB
authors.lastname: Sergienko
authors.forename: A S
authors.initials: AS
authors.lastname: Smetnev
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002310:Cardiomyopathy, Alcoholic / Q000000981:diagnostic imaging / Q000503:physiopathology; D003326:Coronary Circulation; D005080:Exercise Test; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D005082:Physical Exertion; D011877:Radionuclide Imaging; D012146:Rest; D013794:Thallium Radioisotopes; D013997:Time Factors
chemical_list: D013794:Thallium Radioisotopes
vernacular_title: Izuchenie krovosnabzheniia miokarda u bol'nykh khronicheskim alkogolizmom s pomoshch'iu stsintigrafii miokarda s 201Tl.