title: [Behavior of blood pressure and heart rate at rest and during standing in pregnancy].
abstract: This study was designed to answer three questions: 1. Is there a change in systolic blood pressure, diastolic blood pressure and heart rate during pregnancy? 2. Are there alterations of these parameters during standing? 3. Is there a relationship between mean arterial blood pressure and heart rate at rest and during standing? In a randomized study 161 clinically healthy pregnant women between 8th and 41st week of pregnancy were tested with a modified orthostatic test over defined time periods during pregnancy. Systolic and diastolic blood pressure and heart rate were registered in one minute intervals over a 30 minute period with an automatic Dinamap measuring device. This period was subdivided in a 10 minutes lying period, 10 minutes standing period followed by a 10 minutes lying period. There was a marked increase in systolic and diastolic blood pressure at rest with the beginning of the 34th week of gestation (p < 0.05 and p < 0.01). Despite this, maternal heart rate continued to rise over the whole course of pregnancy (p < 0.01). Furthermore, women with a fall in heart rate on standing were only seen in late pregnancy. Finally, pregnant women with a low mean arterial blood pressure (< or = 85 mmHg) did not experience a fall in blood pressure on standing more frequently than normal controls (> 85 mmHg). We conclude that a fall in blood pressure on standing is not dependent on blood pressure at rest during pregnancy.
authors.affiliation: Universitäts-Frauenklinik der Justus-Liebig-Universität Giessen.
authors.forename: M
authors.initials: M
authors.lastname: Hohmann
authors.forename: C
authors.initials: C
authors.lastname: Heimann
authors.forename: P
authors.initials: P
authors.lastname: Kamali
authors.forename: W
authors.initials: W
authors.lastname: Künzel
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D003971:Diastole / Q000502:physiology; D005260:Female; D005865:Gestational Age; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D011187:Posture / Q000502:physiology*; D011247:Pregnancy / Q000502:physiology*; D012016:Reference Values; D013599:Systole / Q000502:physiology
vernacular_title: Das Verhalten des Blutdrucks und der Herzfrequenz in Ruhe und Orthostase während der Schwangerschaft.