title: [Experimental epidural and conduction anesthesia with azacaine].
abstract: Experimental studies were undertaken to examine azacaine used in mice during conduction anesthesia and in rabbits during epidural anesthesia in 0.75, 2 and 0.75, 1% solutions, respectively. It was found that azacaine in the above doses is 1.5-3.5-fold superior to 2% solutions of lidocaine (xycaine) and trimecaine (mesocaine) in their effect duration. Histological studies of the rabbit spinal cord after epidural azacaine administration revealed no significant changes in brain tissues.
authors.forename: I V
authors.initials: IV
authors.lastname: Cherniakova
authors.forename: V N
authors.initials: VN
authors.lastname: Zhukov
authors.forename: S A
authors.initials: SA
authors.lastname: Osipov
authors.forename: A Sh
authors.initials: ASh
authors.lastname: Shadiev
authors.forename: T V
authors.initials: TV
authors.lastname: Skovpen'
mesh_terms: D000765:Anesthesia, Conduction; D000767:Anesthesia, Epidural; D000779:Anesthetics, Local; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D008012:Lidocaine; D008297:Male; D051379:Mice; D010875:Pipecolic Acids; D011817:Rabbits; D014288:Trimecaine
chemical_list: D000779:Anesthetics, Local; D010875:Pipecolic Acids; C069706:azacaine; D008012:Lidocaine; D014288:Trimecaine
vernacular_title: Epidural'naia i provodnikovaia anesteziia azakainom v éksperimente.