title: [Behçet's disease in childhood--case reports and review of literature].
abstract: Two childhood with Behcet's disease were reported. To evaluate the clinical features of Behcet's disease in childhood, fifty eight case studies (domestic; 19 cases, world-wide; 39 cases) were examined from the literature including two cases in our clinics. Oral ulcers (100%), genital ulcers (82.8%), skin manifestations (77.6%), and articular involvement (51.7%) were frequently found as seen in adult cases. Gastrointestinal manifestations were more common in childhood than in adults (50.0% vs. 29.3%). However, ocular inflammatory disease was less frequently seen in pediatric patients as opposed to adults. Three fourth of children with Behçet's disease was effectively treated with oral or intravenous prednisolone. These findings suggested that the criteria for childhood Behçet's disease will be necessary for early and proper diagnosis.
authors.affiliation: Department of Pediatrics, Yokohama-city University School of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Mori
authors.forename: C
authors.initials: C
authors.lastname: Shimizu
authors.forename: T
authors.initials: T
authors.lastname: Kuriyama
authors.forename: M
authors.initials: M
authors.lastname: Ibe
authors.forename: T
authors.initials: T
authors.lastname: Mitsuda
authors.forename: Y
authors.initials: Y
authors.lastname: Aihara
authors.forename: S
authors.initials: S
authors.lastname: Yokota
mesh_terms: D001528:Behcet Syndrome / Q000188:drug therapy / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use; D014844:Vulva / Q000473:pathology
chemical_list: D011239:Prednisolone