[Effect of various specific agents on the heat stability of human serum albumin].
Effect of lipoic acid, 5,5-dithiobis-2-nitrobenzoic acid, monoiodoacetic acid and cystine on thermal stability of human serum albumin was studied by differential scanning calorimetry and electrophoretic methods. Quantitative estimation of the protective effect of these reagents on resistance of 5% solutions of albumin to the temperature influence was studied. It is concluded that all the compounds used protect albumin from polymerization at heating.
Semenova
T V
TV
Azhitskiĭ
G Iu
GIu
Sarnatskaia
V V
VV
Nikolaev
V G
VG
D002152:Calorimetry, Differential Scanning; D003553:Cystine / Q000494:pharmacology*; D004228:Dithionitrobenzoic Acid / Q000494:pharmacology*; D004586:Electrophoresis; D006358:Hot Temperature; D006801:Humans; D007461:Iodoacetates / Q000494:pharmacology*; D019807:Iodoacetic Acid; D012709:Serum Albumin / Q000737:chemistry / Q000187:drug effects*; D008063:Thioctic Acid / Q000494:pharmacology*
D007461:Iodoacetates; D012709:Serum Albumin; D003553:Cystine; D008063:Thioctic Acid; D004228:Dithionitrobenzoic Acid; D019807:Iodoacetic Acid
Vliianie razlichnykh spetsificheskikh agentov na termostabil'nost' syvorotochnogo al'bumina cheloveka.