title: Synthesis and antifungal activity of pyrido[3',2':4,5]thieno[3,2-d]- 1,2,3-triazine derivatives.
abstract: The antimicrobial activity of some pyrido[3',2':4,5]thieno[3,2-d]- 1,2,3-triazine derivatives has been studied. Some compounds proved effective against microorganisms in vitro, compounds 3a and 3c in particular exhibited antifungal activity, comparable to MCZ, against hyphomycetes.
authors.affiliation: Istituto di Chimica Farmaceutica e Tossicologica, Università di Catania, Italia.
authors.forename: F
authors.initials: F
authors.lastname: Guerrera
authors.forename: L
authors.initials: L
authors.lastname: Salerno
authors.forename: M C
authors.initials: MC
authors.lastname: Sarvà
authors.forename: M A
authors.initials: MA
authors.lastname: Siracusa
authors.forename: S
authors.initials: S
authors.lastname: Oliveri
authors.forename: R
authors.initials: R
authors.lastname: Minardi
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008825:Miconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects; D014227:Triazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D014227:Triazines; D008825:Miconazole