[The relationship between concentrations of B(a)P in blood, urine and immune function of coking workers].
The surroundings of a coking plant were contaminated with benzo(a)pyrene [B(a)P] in various degrees. B(a)P in urine and blood of the coking workers was detected, and levels of B(a)P in urine and blood showed correlated. Also, the relationship between the contents of B(a)P in urine and the surroundings of the plant was found. The levels of immunoglobulin (IgG, IgA, IgM) and complement C3 in serum of the coking workers decreased. The levels of IgG and C3 in the workers were significantly different from those in controls. And, the serum contents of B(a)P in the workers also correlated with their immune function.
Lei
Z M
ZM
Department of Health Toxicology, Beijing Medical University.
D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects; D000917:Antibody Formation; D001564:Benzo(a)pyrene / Q000009:adverse effects / Q000032:analysis*; D003033:Coal Tar; D003176:Complement C3 / Q000378:metabolism*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007221:Industry; D008297:Male; D016273:Occupational Exposure
D000395:Air Pollutants, Occupational; D003176:Complement C3; D007074:Immunoglobulin G; D001564:Benzo(a)pyrene; D003033:Coal Tar