title: [Modification of sexual functions by antidepressants].
abstract: Sexual dysfunctions appear to be frequently occurring adverse events in treatment with antidepressants. Due to methodological reasons, a reliable estimation of the frequency of such events is currently not yet possible. There is evidence, that antidepressants could be differentiated with respect to their potency and specificity for disturbances of certain sexual subfunctions according to their pharmacological profile. With SSRIs in particular impaired functions of orgasm and ejaculation can be observed. No deteriorations are reported for buproprion and an improvement of sexual dysfunctions within the course of treatment for moclobemide. Viloxazine and trazodone appear to possess marked stimulating effects on libido and erectile functions. Generally the incidence of sexual adverse events is underestimated, although there is a pronounced impact on patient compliance. Taking into account this well documented side effect, sexual impairments should be monitored carefully within antidepressive treatment.
authors.affiliation: Hoffmann-La Roche AG, Grenzach-Wyhlen.
authors.forename: D
authors.initials: D
authors.lastname: Baier
authors.forename: M
authors.initials: M
authors.lastname: Philipp
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007989:Libido / Q000187:drug effects*; D008297:Male; D012725:Sexual Behavior / Q000187:drug effects*
chemical_list: D000928:Antidepressive Agents
vernacular_title: Die Beeinflussung sexueller Funktionen durch Antidepressiva.