title: CT of the lung in patients with pulmonary emphysema: diagnosis, quantification, and correlation with pathologic and physiologic findings.
abstract: Pulmonary emphysema is a pathologic diagnosis. However, the diagnosis can be made with relative certainty on the basis of clinical and radiologic criteria. The clinical diagnosis of emphysema can be difficult because correlations between results of lung function tests and the extent of emphysema are poor. Additionally, features of other obstructive lung diseases may overlap. From the clinician's standpoint, the main value of differentiating between emphysema and other obstructive diseases of the airways (e.g., asthma and chronic bronchitis) is to (1) establish a prognosis and (2) guide the use of corticosteroid therapy by defining the degree of reversibility that can be expected in patients with limitation in air flow.
authors.affiliation: Department of Radiology (ZA-65), Harborview Medical Center, University of Washington, Seattle 98104.
authors.forename: E J
authors.initials: EJ
authors.lastname: Stern
authors.forename: M S
authors.initials: MS
authors.lastname: Frank
mesh_terms: D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed