Establishment and characterization of new IgD lambda type myeloma cell lines, MOLP-2 and MOLP-3, expressing CD28, CD33 antigens and the IL-6 receptor.
Multiple myeloma cell lines, MOLP-2 and MOLP-3, were established from the peripheral blood of a patient in leukemic phase of multiple myeloma. Both cell lines express the IL-6 receptor, CD28 T cell-associated antigen and CD33 myeloid-associated antigen. IgD lambda immunoglobulin was found in the culture supernatants of both MOLP-2 and MOLP-3.
Matsuo
Y
Y
Fujisaki Cell Center, Hayashibara Biochemical Labs, Okayama, Japan.
Nakamura
S
S
Adachi
T
T
Tsubota
T
T
D015703:Antigens, CD / Q000032:analysis*; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis*; D018106:CD28 Antigens / Q000032:analysis*; D002460:Cell Line; D006801:Humans; D007072:Immunoglobulin D / Q000032:analysis*; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000276:immunology* / Q000473:pathology*; D018123:Receptors, Interleukin / Q000032:analysis*; D019947:Receptors, Interleukin-6; D063268:Sialic Acid Binding Ig-like Lectin 3
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D018106:CD28 Antigens; C571163:CD33 protein, human; D007072:Immunoglobulin D; D007145:Immunoglobulin kappa-Chains; D018123:Receptors, Interleukin; D019947:Receptors, Interleukin-6; D063268:Sialic Acid Binding Ig-like Lectin 3