title: A comparative study of Mycoplasma gallisepticum vaccines in young chickens.
abstract: Ten-day-old leghorn chickens were vaccinated with the F, ts-11, or 6/85 strain of Mycoplasma gallisepticum (MG) via the intraocular route or subcutaneously with MG bacterin and challenged by aerosol with the R strain of MG at 30, 60, or 90 days post-vaccination. Respiratory reaction post-vaccination, serological response, persistence of the vaccine strain, and protection against aerosol challenge were compared. In general, the ts-11 and 6/85 strains induced a milder post-vaccination reaction than F-strain, produced a weaker serological response, and did not persist as long in the upper respiratory tract. The F-strain-vaccinated chickens had the fewest and mildest air-sac lesions post-challenge, the 6/85 and ts-11 groups had somewhat less protection, and bacterin-vaccinated chickens had no detectable protection against airsacculitis. The F-strain-vaccinated chickens also had the fewest MG organisms in the trachea 10 days postchallenge.
authors.affiliation: Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602-4875.
authors.forename: T Y
authors.initials: TY
authors.lastname: Abd-el-Motelib
authors.forename: S H
authors.initials: SH
authors.lastname: Kleven
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000917:Antibody Formation; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D002645:Chickens; D004797:Enzyme-Linked Immunosorbent Assay; D009174:Mycoplasma / Q000276:immunology* / Q000302:isolation & purification; D009175:Mycoplasma Infections / Q000517:prevention & control / Q000662:veterinary*; D011201:Poultry Diseases
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines