A case of IgA deficiency with anti-IgA antibodies and autoimmune thrombocytopenia.
The case of a young woman with autoimmune thrombocytopenia, complete IgA deficiency and anti-IgA antibodies is presented and the role of the AH 8-1 supratype (HLA B8, DR3) is discussed. Such an association necessitates use of IgA-free blood products in order to avoid anaphylactic reactions.
Pierre
P G
PG
ICP-Experimental Medicine Unit, Catholic University of Louvain, Brussels, Belgium.
Ferrant
A
A
Michaux
J L
JL
Vaerman
J P
JP
Van den Bosshe
L
L
D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications / Q000276:immunology*; D005260:Female; D006801:Humans; D017098:IgA Deficiency / Q000150:complications / Q000276:immunology*; D007070:Immunoglobulin A / Q000276:immunology*; D007518:Isoantibodies / Q000097:blood*; D013921:Thrombocytopenia / Q000150:complications / Q000276:immunology*
D007070:Immunoglobulin A; D007518:Isoantibodies