Squamous carcinoma of the oesophagus. Surgery alone or combined with perioperative radiotherapy?
A retrospective comparison of surgery alone and surgery combined with pre- and post-operative radiotherapy was performed for the treatment of squamous carcinoma of the mid and upper oesophagus. Twenty-five ostensibly curative resections for squamous carcinoma of the oesophagus were performed in the period 1974-1987 by the Lewis oesophagectomy. Patients were well matched for histological stage, sex (14F 11M) and age (range 23-69 years). Five year survival for patients receiving surgery alone was 54.5%. Survival for patients who in addition received adjunctive pre- and postoperative radiotherapy of 5700 cGY was not significantly different. Adjunctive pre- and post-operative radiotherapy was considered to facilitate surgical resections but long term survival was not improved.
Purkiss
S F
SF
Department of Surgery, Princess Margaret Hospital, Wiltshire, England, UK.
Huddy
P E
PE
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome