Regulation of coumarin 7-hydroxylation in man.
Pelkonen
O
O
Department of Pharmacology and Toxicology, University of Oulu, Finland.
Rautio
A
A
Raunio
H
H
Mäenpää
J
J
Hakkola
J
J
D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases; D003374:Coumarins / Q000493:pharmacokinetics*; D065637:Cytochrome P-450 CYP2A6; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006801:Humans; D006900:Hydroxylation; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008107:Liver Diseases / Q000378:metabolism; D051379:Mice; D006899:Mixed Function Oxygenases / Q000378:metabolism; D011355:Prodrugs / Q000493:pharmacokinetics*; D014468:Umbelliferones / Q000378:metabolism* / Q000652:urine
D003374:Coumarins; D011355:Prodrugs; D014468:Umbelliferones; C031477:7-hydroxycoumarin; D003577:Cytochrome P-450 Enzyme System; C030123:coumarin; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; D065637:Cytochrome P-450 CYP2A6