Calcein release from temperature-sensitive liposome with or without stirring.
Characteristics of the calcein release from temperature-sensitive liposomes with or without stirring were studied. Calcein release from DPPC(dipalmitoylphosphatidylcholine) REV(reverse phase evaporation vesicle) with stirring occurred at a temperature lower by 8 degrees than that without stirring. DPPC-DSPC(distearoylphosphatidylcholine)-mixed REV showed the maximum release(%) for calcein, near 40 degrees C with stirring and 45 degrees C without stirring.
Ono
A
A
Department of Hospital Pharmacy, Toyama Medical and Pharmaceutical University, Sugitani, Japan.
Yamaguchi
M
M
Horikoshi
I
I
Shintani
T
T
Ueno
M
M
D015060:1,2-Dipalmitoylphosphatidylcholine / Q000378:metabolism*; D002152:Calorimetry, Differential Scanning; D005452:Fluoresceins / Q000378:metabolism*; D008081:Liposomes / Q000378:metabolism*; D013696:Temperature
D005452:Fluoresceins; D008081:Liposomes; D015060:1,2-Dipalmitoylphosphatidylcholine; C007740:fluorexon