title: [Evaluation of drug side effects over a year in a cardiology service].
abstract: An intensive pharmacovigilance survey was carried out over the course of 1 year in cardiology department which revealed 64 reports of adverse drug reactions among 61 hospitalised patients, giving an overall incidence of 2.3%. Most of the patients in whom adverse drug reactions were recorded were elderly and female. The most common adverse events were cardiovascular (72%) and haemorrhagic (9%), and related to drugs given for the treatment of cardiovascular disorders. The symptoms originating from drug therapy were dominated by sinus arrhythmias (25 cases), linked to drugs co-administered that have potentially similar cardiac pharmacodynamic effects. Seven cases of "torsades de pointe" were also observed.
authors.affiliation: Service de cardiologie, C.H.R.U., Angers.
authors.forename: M
authors.initials: M
authors.lastname: Jamaa
authors.forename: P
authors.initials: P
authors.lastname: Laine-Cessac
authors.forename: J
authors.initials: J
authors.lastname: Victor
authors.forename: A
authors.initials: A
authors.lastname: Tadei
authors.forename: P
authors.initials: P
authors.lastname: Allain
mesh_terms: D000328:Adult; D000368:Aged; D016507:Cardiology Service, Hospital; D002317:Cardiovascular Agents / Q000009:adverse effects*; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D002317:Cardiovascular Agents
vernacular_title: Bilan des effets indésirables médicamenteux recueillis au cours d'une année dans un service de cardiologie.