[Analysis of familial aggregation of lung cancer in Xuanwei].
Lung cancer aggregation was analyzed in relatives of the proband compared with those of his/her spouse in 370 nuclear families. Results showed the relatives of the proband had a greater risk of lung cancer compared with those of his/her spouse with an OR of 1.85 (P < 0.01). Even more, female relatives of the proband had much greater risk of lung cancer than those of his/her spouse with and OR of 2.64 (P < 0.01). It suggested relatives of the proband are more vulnerable to lung cancer than those of his/her spouse and genetic factor may contribute to pathogenesis of lung cancer.
Jin
Y T
YT
Department of Environmental Health Anhui Medical University, Hefei.
He
X Z
XZ
D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors