The effects of ninjinyoeito on human vascular endothelial cells.
The effects of Ninjinyoeito on endothelial cells from a human umbilical vein were examined. As a result, the maximum cell density obtained after the addition of Ninjinyoeito was found to be 400 ng/ml, and its inhibitory effect on the development of endothelial injury was also observed. In addition, the levels of LDH and Al-p, which are parameters decreasing with aging, were significantly high. Judging from these results, Ninjinyoeito presumably exerts an anti-aging effect by inhibiting the metabolic aging of cells.
Uchiyama
Y
Y
Kanagawa Rehabilitation Institute, Japan.
Nakajima
S
S
Yoshida
K
K
Mizukawa
H
H
Haruki
E
E
D002452:Cell Count / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D016922:Cellular Senescence / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D014471:Umbilical Veins
D004365:Drugs, Chinese Herbal; C072867:ren-shen-yang-rong-tang; D007770:L-Lactate Dehydrogenase