title: Bilateral optic neuropathy associated with the crest variant of scleroderma.
abstract: We report a case of bilateral optic neuropathy associated with the CREST syndrome, a variant of scleroderma. Immunosuppressive therapy achieved significant improvement of the visual symptoms for two years. The pathophysiological mechanisms underlying this unique association remain unclear.
authors.affiliation: Department of Ophthalmology, Saint-Luc University Hospital, University of Louvain Medical School, Brussels, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Boschi
authors.forename: B
authors.initials: B
authors.lastname: Snyers
authors.forename: M
authors.initials: M
authors.lastname: Lambert
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D017675:CREST Syndrome / Q000150:complications* / Q000188:drug therapy; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D009901:Optic Nerve Diseases / Q000188:drug therapy / Q000209:etiology*; D014792:Visual Acuity; D014794:Visual Fields
chemical_list: D001379:Azathioprine; D008775:Methylprednisolone