Effects of dietary fatty acid composition on glycerophosphate acyltransferase activity in rat adipose tissue and liver.
1. How source of dietary fat influences glycerophosphate acyltransferase (GPAT) activity in homogenates of adipose tissue and liver was determined using 5 rats per diet that contained 12% fat from either corn- (CO), high-oleate-safflower (HOSO), palm- or high-stearate-oils. 2. Activity was greatest in adipose tissue homogenates of rats fed HOSO and CO whereas no treatment effects were observed in liver homogenates. 3. No differences in fat pad weights were observed; thus HOSO- and CO-diets likely depressed other lipid synthetic rates. 4. Data indicate that mono- and diunsaturated fatty acid diets supported greater adipose tissue GPAT activity than did saturated fat diets when fed to rats.
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Department of Animal Science, University of Wyoming, Laramie 82071-3684.
D000273:Adipose Tissue / Q000201:enzymology*; D000818:Animals; D003314:Corn Oil; D004042:Dietary Fats, Unsaturated / Q000032:analysis*; D005227:Fatty Acids / Q000032:analysis*; D005992:Glycerol-3-Phosphate O-Acyltransferase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008297:Male; D019301:Oleic Acid; D009829:Oleic Acids; D000073878:Palm Oil; D010938:Plant Oils; D051381:Rats; D017207:Rats, Sprague-Dawley; D012450:Safflower Oil; D013229:Stearic Acids
D004042:Dietary Fats, Unsaturated; D005227:Fatty Acids; D009829:Oleic Acids; D010938:Plant Oils; D013229:Stearic Acids; D019301:Oleic Acid; C031183:stearic acid; D000073878:Palm Oil; D012450:Safflower Oil; D003314:Corn Oil; D005992:Glycerol-3-Phosphate O-Acyltransferase