title: Prolonged intragraft urokinase with a new infusion wire: improved short-term results.
abstract: Patients with aged saphenous vein grafts and recurrent symptoms of angina are being seen with increasing frequency [Bourassa: J Am Coll Cardiol 17:1081-1083, 1991]. The treatment of these patients remains a dilemma. Direct balloon angioplasty is frequently complicated by distal embolization and early restenosis [Aureran and Gruentzig: Am J Cardiol 53:953-954, 1984]. There is evidence that thrombus plays a significant role in this occlusive process [Hartmann et al.: J Am Coll Cardiol 18:1517-1523, 1991]. Prolonged intragraft urokinase infusion with a new multiside hole infusion catheter debulks thrombus and permits balloon angioplasty without the usual complications.
authors.affiliation: University Hospital, Augusta, Georgia.
authors.forename: P E
authors.initials: PE
authors.lastname: Cundey
authors.forename: R R
authors.initials: RR
authors.lastname: Whitlock
authors.forename: J
authors.initials: J
authors.lastname: Norman
authors.forename: M
authors.initials: M
authors.lastname: Edwards
authors.forename: P E
authors.initials: PE
authors.lastname: Cundey
mesh_terms: D000787:Angina Pectoris / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D015331:Cohort Studies; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery*; D004334:Drug Administration Schedule; D004867:Equipment Design; D006083:Graft Occlusion, Vascular / Q000188:drug therapy*; D006801:Humans; D011183:Postoperative Complications / Q000188:drug therapy*; D012008:Recurrence; D012501:Saphenous Vein / Q000637:transplantation*; D015912:Thrombolytic Therapy / Q000295:instrumentation*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D014568:Urokinase-Type Plasminogen Activator