[Study on the relationship between dietary aflatoxin B1 levels in foods and aflatoxin M1 excretion levels in children's urine in Guangxi].
617 children in high and low liver cancer incidence areas of Guangxi were observed for a study on the relationship between the dietary Aflatoxin B1 (AFB1) levels and Aflatoxin M1 (AFM1) excretion amounts in urine. The average amount of Aflatoxin B1 absorbed by children within 24 hours was 0.0883 x 10(-9) micrograms, (0.1232 x 10(-9)) in high liver cancer incidence area (LCIA), and 0.0306 x 10(-9) in low LCIA (P < 0.001). The average amount of AFM1 excreted in the children's urine within 24 hours was 0.0020 x 10(-9) micrograms, (0.0027 x 10(-9) in high LCIA, and 0.0010 x 10(-9) in low LCIA (P < 0.001). The conversion ratio from AFB1 to AFM1 excreted from urine was 2.27% in 24 hours after the children consumed AFB1 from foods. The ratio of conversion was 2.19% and 3.27% for the children who life in high and low LCIA respectively, it was 1.75% for the boys, 2.97% for the girls.
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Guangxi Cancer Institute, Nanning.
D000293:Adolescent; D016604:Aflatoxin B1 / Q000032:analysis*; D016607:Aflatoxin M1 / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D002523:Edible Grain; D005260:Female; D005516:Food Microbiology; D005658:Fungi; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000517:prevention & control*; D008297:Male
D016607:Aflatoxin M1; D016604:Aflatoxin B1