title: Amino acid sequence of glutathione S-transferase a from guinea pig liver.
abstract: The amino acid sequence of glutathione S-transferase a from guinea pig liver was determined. Glutathione S-transferase a was composed of two identical subunits, each comprising 218 amino acid residues. The amino acid sequence of glutathione S-transferase a exhibited 73% homology with that of human glutathione S-transferase Ha, 69% with that of rat glutathione S-transferase Ya, and 68% with that of rat glutathione S-transferase Yc, which are known to belong to class Alpha. From the above result, together with previous observations on its substrate specificity, it was concluded that glutathione S-transferase a belonged to class Alpha.
authors.affiliation: Laboratory of Biochemistry, Kobe Yamate Women's College, Kobe.
authors.forename: K
authors.initials: K
authors.lastname: Kamei-Hayashi
authors.forename: R
authors.initials: R
authors.lastname: Oshino
authors.forename: S
authors.initials: S
authors.lastname: Hara
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003488:Cyanogen Bromide; D005982:Glutathione Transferase / Q000145:classification / Q000302:isolation & purification*; D006168:Guinea Pigs; D006801:Humans; D008099:Liver / Q000201:enzymology*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010446:Peptide Fragments / Q000302:isolation & purification; D051381:Rats; D017386:Sequence Homology, Amino Acid; D014357:Trypsin
chemical_list: D010446:Peptide Fragments; D005982:Glutathione Transferase; D014357:Trypsin; D003488:Cyanogen Bromide