title: A survey of the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in Prader-Willi syndrome.
abstract: Prader-Willi Syndrome (PWS) is a congenital disorder characterized by hyperphagia as well as by other behavioral disturbances such as self-mutilation and temper outbursts. Some of these symptoms have been reported to respond to psychotropic medications. A systematic survey was conducted to gather information on the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in PWS. Both compulsive and impulsive-aggressive symptoms are frequent in this population. Pharmacotherapeutic intervention may have a role in the management of these symptoms. Rigorous diagnostic and treatment studies should be undertaken in this population.
authors.affiliation: Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York.
authors.forename: D J
authors.initials: DJ
authors.lastname: Stein
authors.forename: J
authors.initials: J
authors.lastname: Keating
authors.forename: H J
authors.initials: HJ
authors.lastname: Zar
authors.forename: E
authors.initials: E
authors.lastname: Hollander
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003680:Deglutition Disorders / Q000209:etiology; D004358:Drug Therapy; D006801:Humans; D001523:Mental Disorders / Q000209:etiology; D011218:Prader-Willi Syndrome / Q000175:diagnosis* / Q000188:drug therapy* / Q000523:psychology; D012652:Self Mutilation / Q000209:etiology; D011795:Surveys and Questionnaires