title: Retrobulbar anesthesia with and without hyaluronidase in extracapsular cataract surgery. A prospective, randomized, double-blind study.
abstract: Eighty patients with senile cataract were subjected to a planned extracapsular cataract extraction (ECCE) with implantation of a posterior chamber intraocular lens. Retrobulbar anesthesia was administered by injection of 4 mg lidocaine 2% with adrenalin. In 40 patients 150 I.U. hyaluronidase (Kinetin) was added to the anesthesia. The hyaluronidase group had a significantly lower frequency of iris prolapse, and deeper anterior chamber, both before and after expression of the lens nucleus. Possible mechanisms explaining the beneficial effect of hyaluronidase in extracapsular cataract surgery are discussed.
authors.affiliation: Department of Ophthalmology, University of Bergen, Norway.
authors.forename: J
authors.initials: J
authors.lastname: Krohn
authors.forename: J H
authors.initials: JH
authors.lastname: Seland
authors.forename: G
authors.initials: G
authors.lastname: Høvding
authors.forename: T
authors.initials: T
authors.lastname: Bertelsen
authors.forename: H
authors.initials: H
authors.lastname: Aasved
authors.forename: O H
authors.initials: OH
authors.lastname: Haugen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000772:Anesthesia, Local / Q000379:methods*; D002387:Cataract Extraction; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000008:administration & dosage*; D007499:Iris Diseases / Q000517:prevention & control; D007910:Lenses, Intraocular; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011391:Prolapse; D011446:Prospective Studies
chemical_list: D008012:Lidocaine; D006821:Hyaluronoglucosaminidase; D004837:Epinephrine