Agonist activation of transfected human M1 muscarinic acetylcholine receptor in Chinese hamster ovary cells results in concurrent downregulation of Gq alpha and G11 alpha.
Mullaney
I
I
Department of Biochemistry, University of Glasgow, U.K.
Milligan
G
G
D000818:Animals; D016466:CHO Cells; D002217:Carbachol / Q000494:pharmacology*; D006224:Cricetinae; D004591:Electrophoresis, Polyacrylamide Gel; D019204:GTP-Binding Proteins / Q000096:biosynthesis / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D015151:Immunoblotting; D046911:Macromolecular Substances; D011976:Receptors, Muscarinic / Q000187:drug effects / Q000302:isolation & purification / Q000378:metabolism*; D015290:Second Messenger Systems; D014162:Transfection
D046911:Macromolecular Substances; D011976:Receptors, Muscarinic; D002217:Carbachol; D019204:GTP-Binding Proteins