title: High-affinity and potent, water-soluble 5-amino-1,4-benzodiazepine CCKB/gastrin receptor antagonists containing a cationic solubilizing group.
authors.affiliation: Merck, Sharp and Dohme Research Laboratories, Neuroscience Research Center, Harlow Essex, United Kingdom.
authors.forename: G A
authors.initials: GA
authors.lastname: Showell
authors.forename: S
authors.initials: S
authors.lastname: Bourrain
authors.forename: J G
authors.initials: JG
authors.lastname: Neduvelil
authors.forename: S R
authors.initials: SR
authors.lastname: Fletcher
authors.forename: R
authors.initials: R
authors.lastname: Baker
authors.forename: A P
authors.initials: AP
authors.lastname: Watt
authors.forename: A E
authors.initials: AE
authors.lastname: Fletcher
authors.forename: S B
authors.initials: SB
authors.lastname: Freedman
authors.forename: J A
authors.initials: JA
authors.lastname: Kemp
authors.forename: G R
authors.initials: GR
authors.lastname: Marshall
mesh_terms: D000818:Animals; D001569:Benzodiazepines / Q000138:chemical synthesis / Q000494:pharmacology*; D006801:Humans; D011949:Receptors, Cholecystokinin / Q000037:antagonists & inhibitors*; D012995:Solubility; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D011949:Receptors, Cholecystokinin; D001569:Benzodiazepines