Definition of early Ca2+ signals induced by anti-CD3 antibody in a human Jurkat T-cell line using a selective protein kinase C inhibitor, Ro 31-8425.
Conroy
L A
LA
Roche Products Research Centre, Welwyn Garden City, Herts., UK.
Merritt
J E
JE
Giafi
C F
CF
Lamont
A G
AG
Hallam
T J
TJ
D000470:Alkaloids / Q000494:pharmacology; D000906:Antibodies / Q000494:pharmacology*; D017252:CD3 Complex / Q000187:drug effects / Q000276:immunology / Q000502:physiology*; D002118:Calcium / Q000378:metabolism*; D002460:Cell Line; D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D007700:Kinetics; D008301:Maleimides / Q000494:pharmacology*; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology*; D019311:Staurosporine; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000378:metabolism*; D014407:Tumor Cells, Cultured
D000470:Alkaloids; D000906:Antibodies; D017252:CD3 Complex; D007211:Indoles; D008301:Maleimides; C071924:Ro 31-8425; D011493:Protein Kinase C; D019311:Staurosporine; D002118:Calcium