Chemotherapy of Entamoeba histolytica: studies in vitro with bacitracin and its zinc salt.
Twenty-one Entamoeba histolytica isolates from a range of geographical locations and representing 3 different zymodemes were tested under xenic anaerobic conditions for their sensitivities to bacitracin and bactracin zinc. Isolates were over 13 times more sensitive to bacitracin zinc than to bacitracin. Our results indicate that bacitracin zinc may form the basis of an alternative non-toxic treatment of luminal amoebiasis.
Andrews
B J
BJ
Centre for International Health, University of Bergen, Haukeland Hospital, Norway.
Bjorvatn
B
B
D000818:Animals; D001414:Bacitracin / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004748:Entamoeba histolytica / Q000145:classification / Q000187:drug effects* / Q000472:pathogenicity; D006801:Humans; D066298:In Vitro Techniques
D001414:Bacitracin