title: Clinicopathologic correlation of a macular hole treated by cortical vitreous peeling and gas tamponade.
abstract: OBJECTIVE
  To study the histopathology of a stage III macular hole that had been treated by vitrectomy with cortical vitreous and epicortical vitreous membrane peeling and gas tamponade.
  
  
  METHODS
  The light and electron microscopic features of a treated macular hole were studied.
  
  
  RESULTS
  A 16-microns-wide break was present in the external limiting membrane. This was sealed by Müller cell processes. Photoreceptors adjacent to the healed defect appeared normal. No cystoid macular edema was present.
  
  
  CONCLUSIONS
  Cortical vitreous peeling and gas tamponade can allow the macular hole to settle and the edges to re-approximate. The residual defect can be sealed by Müller cells.
authors.affiliation: Eye Pathology Laboratory, Wilmer Ophthalmological Institute, Baltimore 21287-9248.
authors.forename: S A
authors.initials: SA
authors.lastname: Madreperla
authors.forename: G L
authors.initials: GL
authors.lastname: Geiger
authors.forename: M
authors.initials: M
authors.lastname: Funata
authors.forename: Z
authors.initials: Z
authors.lastname: de la Cruz
authors.forename: W R
authors.initials: WR
authors.lastname: Green
mesh_terms: D000368:Aged; D002462:Cell Membrane; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D009457:Neuroglia / Q000648:ultrastructure; D012160:Retina / Q000648:ultrastructure; D012167:Retinal Perforations / Q000473:pathology* / Q000601:surgery*; D013459:Sulfur Hexafluoride; D014821:Vitrectomy
chemical_list: D013459:Sulfur Hexafluoride