Human cancer vaccines.
Immune T cells recognize peptide antigens presented to them within self-MHC molecules. Thus auto-tumor reactive lymphocyte populations can be generated. Antigenic expression can be modified and intensified and reactive lymphocyte populations can be expanded. Active immunization of the tumor-bearing human host can induce immune reactions of tumor rejection strength. Frequently, micrometastases can be eliminated and occasionally partial or complete remissions of gross metastases can be induced.
Sinkovics
J
J
Cancer Institute, St. Joseph's Hospital, Tampa, Florida 33607.
Horvath
J
J
Szabo-Szabari
M
M
D001500:BCG Vaccine / Q000276:immunology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008545:Melanoma / Q000276:immunology; D009369:Neoplasms / Q000276:immunology*; D009522:Newcastle disease virus / Q000276:immunology; D014611:Vaccination; D014612:Vaccines / Q000276:immunology*
D001500:BCG Vaccine; D014612:Vaccines