[Transportation trends after rat renal intracapsular injection of Salvia miltiorrhizae].
The concentration of Salvia miltiorrhizae (SM) was detected at different time after renal intracapsular injection in S.D rats. It showed that SM concentration was higher in kidney than in plasma (P < 0.05). SM concentration in kidney increased gradually, it reached the peak at 24 hour and still remained in higher level at 48 hour. The SM injected in renal capsule could be passively transported to renal tissue and maintained at a high level. This result demonstrated that renal intracapsular injection could be applied as an important therapeutical method for different renal disease.
Tian
S
S
Affiliated People's Hospital, Beijing Medical University.
Gao
H B
HB
Tao
F
F
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000493:pharmacokinetics*; D007668:Kidney / Q000378:metabolism*; D008297:Male; D010936:Plant Extracts; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats; D017207:Rats, Sprague-Dawley; D027561:Salvia miltiorrhiza
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts