A survey of the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in Prader-Willi syndrome.
Prader-Willi Syndrome (PWS) is a congenital disorder characterized by hyperphagia as well as by other behavioral disturbances such as self-mutilation and temper outbursts. Some of these symptoms have been reported to respond to psychotropic medications. A systematic survey was conducted to gather information on the phenomenology and pharmacotherapy of compulsive and impulsive-aggressive symptoms in PWS. Both compulsive and impulsive-aggressive symptoms are frequent in this population. Pharmacotherapeutic intervention may have a role in the management of these symptoms. Rigorous diagnostic and treatment studies should be undertaken in this population.
Stein
D J
DJ
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York.
Keating
J
J
Zar
H J
HJ
Hollander
E
E
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003680:Deglutition Disorders / Q000209:etiology; D004358:Drug Therapy; D006801:Humans; D001523:Mental Disorders / Q000209:etiology; D011218:Prader-Willi Syndrome / Q000175:diagnosis* / Q000188:drug therapy* / Q000523:psychology; D012652:Self Mutilation / Q000209:etiology; D011795:Surveys and Questionnaires