[Risk related to withdrawal from non-psychotropic drugs].
A review of the available literature concerning sudden withdrawal of drugs shows that withdrawal syndrome have occurred with centrally antihypertensive drugs, beta-blockers on anginal patients, antiparkinsonian drugs and glucocorticoids. Because of a lack of controlled trials led among a large number of individuals, the correct frequency of this withdrawal syndrome is unknown. In most patients, it's hard to distinguish a return to a previous state from an overshoot phenomenon. In that way, gradual and supervised withdrawal of these agents should prevent the complication of sudden cessation of these therapy.
Chichmanian
R M
RM
Centre Régional de Pharmacovigilance, Hôpital Pasteur, Nice.
Gustovic
P
P
Spreux
A
A
Baldin
B
B
D000787:Angina Pectoris / Q000188:drug therapy; D000959:Antihypertensive Agents / Q000009:adverse effects; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D010300:Parkinson Disease / Q000188:drug therapy; D012307:Risk Factors; D013375:Substance Withdrawal Syndrome
D000959:Antihypertensive Agents; D005938:Glucocorticoids
Risques liés à l'arrêt des médicaments non psychotropes.