The beta-thalassemia frameshift at codon 8 (-AA) observed in four Chinese of the Uygur nationality.
During a survey for beta-thalassemia in Kashi City, Xinjiang Province, P.R. China, four unrelated Uygur students were identified as heterozygotes for the beta-thalassemia frameshift at codon 8 (-AA). Detection was with the polymerase chain reaction combined with allele-specific oligonucleotide hybridization. This beta-thalassemia allele has not been observed in the Chinese population before and might be rather specific for the Uygur nationality.
Li
H J
HJ
Laboratory of Medical Genetics, Western Region Hospital, Urumqi, Xinjiang, P.R. China.
Yu
W Z
WZ
Zhou
C W
CW
Hao
X J
XJ
Zhou
Y
Y
D044466:Asian People / Q000235:genetics*; D001483:Base Sequence; D003062:Codon; D005260:Female; D006579:Heterozygote; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D017086:beta-Thalassemia / Q000235:genetics*
D003062:Codon