title: Susceptibility to Eimeria tenella of chickens and chicken embryos of partly inbred lines possessing homozygous major histocompatibility complex haplotypes.
abstract: Susceptibility to Eimeria tenella infection of chicken embryos and chickens of partly inbred lines possessing different major histocompatibility complex haplotypes was investigated. Chicken embryos of line H-B2 possessing B2 homozygous haplotype showed lower mortality and higher oocyst production than embryos of line H-B15 possessing B15 homozygous haplotype. Embryos of line H-B2 chickens were considered more resistant to E. tenella infection than those of line H-B15. Seven days after 10-day-old chickens were infected with E. tenella, the two lines showed no significant differences in percent bodyweight gain, cecal lesion score, and oocyst production; they differed significantly only in cecal shrinkage. Results suggest that the B system affects chicken embryos and chickens differently in susceptibility to E. tenella infection.
authors.affiliation: Department of Animal Microbiology and Parasitology, Tohoku University, Sendai, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Nakai
authors.forename: K
authors.initials: K
authors.lastname: Edamura
authors.forename: K
authors.initials: K
authors.lastname: Kanazawa
authors.forename: S
authors.initials: S
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Hirota
authors.forename: K
authors.initials: K
authors.lastname: Ogimoto
mesh_terms: D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D003048:Coccidiosis / Q000276:immunology / Q000401:mortality / Q000662:veterinary*; D016786:Eimeria tenella; D020022:Genetic Predisposition to Disease; D006128:Growth; D006239:Haplotypes; D006720:Homozygote; D007178:Inbreeding; D008285:Major Histocompatibility Complex; D011201:Poultry Diseases; D015430:Weight Gain