title: Repeated and persistent infection with Chlamydia and the development of chronic inflammation and disease.
abstract: Chlamydia trachomatis is an important human pathogen that mediates disease processes capable of inflicting permanent damage. Aggressive inflammatory responses to repeated infections, and to a persistent form of this intracellular bacterium, are thought to initiate the pathogenic events that lead to the debilitating sequelae of blinding trachoma and infertility.
authors.affiliation: Dept of Medical Microbiology and Immunology, University of Wisconsin, Madison 53706.
authors.forename: W L
authors.initials: WL
authors.lastname: Beatty
authors.forename: G I
authors.initials: GI
authors.lastname: Byrne
authors.forename: R P
authors.initials: RP
authors.lastname: Morrison
mesh_terms: D002690:Chlamydia Infections / Q000276:immunology* / Q000382:microbiology / Q000473:pathology*; D002692:Chlamydia trachomatis / Q000254:growth & development / Q000276:immunology / Q000378:metabolism*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007246:Infertility / Q000209:etiology; D007371:Interferon-gamma / Q000276:immunology; D008297:Male; D012008:Recurrence; D014141:Trachoma / Q000276:immunology* / Q000473:pathology
chemical_list: D007371:Interferon-gamma