Long-term treatment with rifaximin and lactobacilli in post-diverticulitic stenoses of the colon.
The authors report their endoscopic experience in the treatment of intestinal inflammatory complications and their prevention with cyclic antibiotic treatment (rifaximin 400 mg b.i.d. for 7 days/month), followed by recolonizing treatment with lactobacilli (2 capsules in the morning for 7 days/month), for an overall period of 12 months. In all 79 cases (45 males and 34 females, mean age 63 years, range 55-75 years), the treatment proved capable of controlling the symptoms and averting the onset of the complications which follow attacks of acute diverticulitis. These complications include uncontrollable sepsis, free perforation of a hollow viscus, evolutive fistulation, intestinal occlusion, abscesses not drained percutaneously, all factors which necessitate urgent elective surgery. Rifaximin, together with lactobacillus treatment, proved to be effective, well-tolerated and safe, and can thus be considered an indispensable aid in the treatment of diverticular disease and in the prevention of its complications.
Giaccari
S
S
Divisione di Gastroenterologia, O.C. Galatina, Istituto Wassermann, Alfa Wasserman S.p.A.
Tronci
S
S
Falconieri
M
M
Ferrieri
A
A
D000368:Aged; D004239:Diverticulitis, Colonic / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D007778:Lactobacillus; D008297:Male; D008875:Middle Aged; D012294:Rifamycins / Q000627:therapeutic use*; D000078262:Rifaximin
D012294:Rifamycins; D000078262:Rifaximin