Targeting of viral glycoproteins to the Golgi complex.
Certain enveloped viruses are known to assemble on membranes of the Golgi complex. Intracellular budding is facilitated by targeting of the viral glycoproteins to this organelle. It is likely that these viral glycoproteins are retained in the Golgi by the same means as are endogenous Golgi proteins. Consequently, the study of Golgi-specific viral proteins has provided important clues to the nature of Golgi retention signals.
Hobman
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TC
Division of Cellular and Molecular Medicine, University of California, San Diego, La Jolla 92093-0651.
D000818:Animals; D001692:Biological Transport; D002043:Bunyaviridae; D016466:CHO Cells; D003332:Coronaviridae; D006224:Cricetinae; D006023:Glycoproteins / Q000378:metabolism*; D006056:Golgi Apparatus / Q000378:metabolism*; D012328:RNA Viruses / Q000378:metabolism*; D012412:Rubella virus; D014764:Viral Proteins / Q000378:metabolism*
D006023:Glycoproteins; D014764:Viral Proteins