title: Malignant solitary fibrous tumor of the pleura.
abstract: We describe a case of malignant solitary fibrous tumor of the pleura in a 15-year-old female who presented clinically with back pain. Grossly, the tumor had a pedicle attached to the pleura and histologically showed proliferating spindle-shaped cells with a high mitotic index. Immunohistochemical and ultrastructural features were consistent with a tumor of fibroblastic origin. Flow cytometric DNA analysis revealed an aneuploid population among the tumor cells.
authors.affiliation: Department of Pathology, Children's Memorial Hospital, Northwestern University, Chicago, Illinois 60614.
authors.forename: I
authors.initials: I
authors.lastname: Uzoaru
authors.forename: P
authors.initials: P
authors.lastname: Chou
authors.forename: M
authors.initials: M
authors.lastname: Reyes-Mugica
mesh_terms: D000293:Adolescent; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007124:Immunoenzyme Techniques; D018218:Neoplasms, Fibrous Tissue / Q000473:pathology* / Q000648:ultrastructure; D010997:Pleural Neoplasms / Q000473:pathology* / Q000648:ultrastructure