title: The thermostability of vaccines. Technologies for improving the thermostability of the oral poliovirus vaccine.
abstract: Technologies that promise to enhance the stability of vaccines are likely to be determined by the product-specific physical structure and biological functions of the specific vaccine immunogens. Research may define the extent to which the stability of oral poliovirus vaccine may be improved by the addition of certain antiviral components that bind to the poliovirus capsid or by the application of novel drying technologies.
authors.affiliation: University of North Carolina, Chapel Hill.
authors.forename: S M
authors.initials: SM
authors.lastname: Lemon
authors.forename: J B
authors.initials: JB
authors.lastname: Milstien
mesh_terms: D002213:Capsid; D015195:Drug Design; D004341:Drug Evaluation; D004355:Drug Stability; D004356:Drug Storage; D006358:Hot Temperature / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D011055:Poliovirus Vaccine, Oral / Q000737:chemistry*; D012367:RNA, Viral
chemical_list: D011055:Poliovirus Vaccine, Oral; D012367:RNA, Viral