title: Distribution of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in rat testis mitochondria.
abstract: The distribution of phospholipid hydroperoxide glutathione peroxidase (PHGPx) in isolated rat testis mitochondria was investigated, using a reverse sucrose density gradient centrifugation procedure for the separation of the inner and outer membranes and the contact sites between the two membranes. The results indicate that PHGPx is largely localized in the contact sites fraction. This finding might therefore suggest that the enzyme has more than just an antioxidant function.
authors.affiliation: Department of Biochemistry, Biophysics and Macromolecular Chemistry, University of Trieste, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Godeas
authors.forename: G
authors.initials: G
authors.lastname: Sandri
authors.forename: E
authors.initials: E
authors.lastname: Panfili
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology; D005979:Glutathione Peroxidase / Q000378:metabolism*; D007425:Intracellular Membranes / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008297:Male; D008928:Mitochondria / Q000201:enzymology*; D000080662:Phospholipid Hydroperoxide Glutathione Peroxidase; D051381:Rats; D013737:Testis / Q000201:enzymology*
chemical_list: D000080662:Phospholipid Hydroperoxide Glutathione Peroxidase; D005979:Glutathione Peroxidase