Dynamic behavior of 110mAg in sheep tissues.
The transfer coefficient of 110mAg to a range of sheep tissues and its biological half-life in these tissues has been determined. Liver was shown to be the major site of 110mAg deposition and retention, with a transfer coefficient of Ff 7.1 d kg-1 and a biological half-life of 79 d. These results also suggest that previous estimates of the transfer of silver to muscle were too high, although further work would be required to confirm this. There is a need for accurate data which can be used to predict the transfer of 110mAg to food-producing animals.
Beresford
N A
NA
Institute of Terrestrial Ecology, Merlewood Research Station, Grange-over-Sands, Cumbria, UK.
Mayes
R W
RW
Crout
N M
NM
Howard
B J
BJ
Kanyar
B
B
D000818:Animals; D005260:Female; D011868:Radioisotopes / Q000493:pharmacokinetics*; D012756:Sheep / Q000378:metabolism*; D012834:Silver / Q000493:pharmacokinetics*; D014018:Tissue Distribution
D011868:Radioisotopes; D012834:Silver