title: Low doses of interleukin-2 can cure large bovine ocular squamous cell carcinoma.
abstract: Four cows bearing large Ocular Squamous Cell Carcinomas (BOSCC) were treated by 10 intratumoral injections (Monday-Friday for 2 consecutive weeks) of 200,000 U Interleukin-2 (Cetus). Tumors regressed in 2 out of 4 cases. This result shows that even large tumors may regress after local IL-2 treatment.
authors.affiliation: Department of Pathology, Academical Hospital Utrecht, The Netherlands.
authors.forename: W
authors.initials: W
authors.lastname: Den Otter
authors.forename: F W
authors.initials: FW
authors.lastname: Hill
authors.forename: W R
authors.initials: WR
authors.lastname: Klein
authors.forename: J W
authors.initials: JW
authors.lastname: Koten
authors.forename: P A
authors.initials: PA
authors.lastname: Steerenberg
authors.forename: P H
authors.initials: PH
authors.lastname: De Mulder
authors.forename: V P
authors.initials: VP
authors.lastname: Rutten
authors.forename: E J
authors.initials: EJ
authors.lastname: Ruitenberg
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology / Q000628:therapy*; D005142:Eyelid Neoplasms / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D005260:Female; D015552:Injections, Intralesional; D007376:Interleukin-2 / Q000008:administration & dosage*
chemical_list: D007376:Interleukin-2