title: Analysis of method-comparison data.
abstract: Method-comparison studies, in which new 'candidate' techniques are compared with an established 'gold standard', feature commonly in optometric research. Investigators often analyse their findings using least squares regression, Pearson's product-moment correlation coefficient and the paired t-test. We describe more appropriate methods which include: the 'limits of agreement', the intraclass correlation coefficient, and Deming's method for estimating a straight line fit. Comparisons between methods are made with the aid of a computer simulation. Computer program listings are provided to assist in implementing the analyses.
authors.affiliation: Department of Ophthalmology, University of Birmingham, UK.
authors.forename: D E
authors.initials: DE
authors.lastname: Shaw
authors.forename: H S
authors.initials: HS
authors.lastname: Jones
authors.forename: M J
authors.initials: MJ
authors.lastname: Moseley
mesh_terms: D003198:Computer Simulation; D009907:Optometry; D012044:Regression Analysis; D012107:Research Design; D012984:Software; D013223:Statistics as Topic / Q000379:methods*