title: [IgG subclasses in children with recurrent respiratory diseases].
abstract: The authors examined IgG sub-classes, using the ELISA method, in 35 patients with relapsing respiratory diseases and 27 children of a control group aged 3-15 years. In children with relapsing respiratory diseases without deficiency of the main immunoglobulin classes they found a statistically significantly reduced value in sub-class IgG2 (P < or = 0.01). The changes found in other sub-classes were not statistically significant. The authors draw attention to the fact that deficiency in IgG sub-classes should be considered in case of repeated respiratory infections caused by encapsulated microorganisms--H. influenzae, Str. pneumoniae--and also when reduced levels of IgG and IgA are found. However, even normal levels do not rule out deficiency.
authors.affiliation: II. detská klinika DFNsP, Bratislava.
authors.forename: A
authors.initials: A
authors.lastname: Kapellerová
authors.forename: A
authors.initials: A
authors.lastname: Kasanická
authors.forename: J
authors.initials: J
authors.lastname: Ponec
authors.forename: A
authors.initials: A
authors.lastname: Vasilenková
authors.forename: D
authors.initials: D
authors.lastname: Cingelová
authors.forename: Z
authors.initials: Z
authors.lastname: Kuková
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis / Q000145:classification*; D012008:Recurrence; D012140:Respiratory Tract Diseases / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G
vernacular_title: Podtriedy IgG u detí s recidivujúcimi respiracnými chorobami.