[Morphology of recent meningococcal infections in children].
An analysis of 108 cases of children's death which occurred in 1981-1991 from hypertoxic meningococcal infection (MI) in St. Petersburg is presented. Serogroup B meningococcus as a causative agent was found in 44% of the cases. The role in the thanatogenesis of inflammatory and immune reactions, viral-bacterial associations was shown on the basis of detailed study of 47 cases. Hemorrhagic adrenal necrosis was diagnosed in 94.7% of the cases. Two clinicomorphological variants of the disease are distinguished: 1) variant with a moderate hemorrhagic eruption without pronounced kidney lesion, 2) variant with an abundant confluent rash and pronounced kidney lesions and choroid plexus immune lesions.
Shvets
O L
OL
Tsinzerling
V A
VA
Sorokina
M N
MN
D000311:Adrenal Glands / Q000473:pathology; D001344:Autopsy; D002675:Child, Preschool; D006470:Hemorrhage / Q000209:etiology / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008589:Meningococcal Infections / Q000150:complications / Q000473:pathology*; D009336:Necrosis; D009345:Neisseria meningitidis / Q000302:isolation & purification; D012189:Retrospective Studies; D012698:Serologic Tests
Morfologiia sovremennoĭ meningokokkovoĭ infektsii u deteĭ.