[Evaluation of drug side effects over a year in a cardiology service].
An intensive pharmacovigilance survey was carried out over the course of 1 year in cardiology department which revealed 64 reports of adverse drug reactions among 61 hospitalised patients, giving an overall incidence of 2.3%. Most of the patients in whom adverse drug reactions were recorded were elderly and female. The most common adverse events were cardiovascular (72%) and haemorrhagic (9%), and related to drugs given for the treatment of cardiovascular disorders. The symptoms originating from drug therapy were dominated by sinus arrhythmias (25 cases), linked to drugs co-administered that have potentially similar cardiac pharmacodynamic effects. Seven cases of "torsades de pointe" were also observed.
Jamaa
M
M
Service de cardiologie, C.H.R.U., Angers.
Laine-Cessac
P
P
Victor
J
J
Tadei
A
A
Allain
P
P
D000328:Adult; D000368:Aged; D016507:Cardiology Service, Hospital; D002317:Cardiovascular Agents / Q000009:adverse effects*; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
D002317:Cardiovascular Agents
Bilan des effets indésirables médicamenteux recueillis au cours d'une année dans un service de cardiologie.