title: [Granulomatous endocarditis caused by streptococcus].
abstract: Two cases of granulomatous endocarditis are reported. The patients developed aortal endocarditis refractory to antibiotics. Therefore, aortal valve replacement was performed. In both cases, Streptococcus viridans was demonstrated in culture and bacterioscopically to be the cause of infection. Histological examination of the valves showed characteristic endocarditis with fibrinoid necrosis and histiocytic granulomas. Streptococci were found in the cytoplasm of macrophages. The possible causes of this special form of infectious endocarditis are discussed.
authors.affiliation: Institut für Pathologie der Universität Würzburg.
authors.forename: A M
authors.initials: AM
authors.lastname: Gassel
authors.forename: M M
authors.initials: MM
authors.lastname: Ott
authors.forename: D
authors.initials: D
authors.lastname: Piridou-Bagatzouni
authors.forename: K
authors.initials: K
authors.lastname: Sandhage
authors.forename: M
authors.initials: M
authors.lastname: Lebert
authors.forename: H K
authors.initials: HK
authors.lastname: Müller-Hermelink
mesh_terms: D000293:Adolescent; D000368:Aged; D001021:Aortic Valve / Q000473:pathology / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000473:pathology* / Q000601:surgery; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000473:pathology* / Q000601:surgery; D005260:Female; D006099:Granuloma / Q000473:pathology* / Q000601:surgery; D006350:Heart Valve Prosthesis; D006801:Humans; D013290:Streptococcal Infections / Q000473:pathology* / Q000601:surgery; D013291:Streptococcus / Q000648:ultrastructure
vernacular_title: Granulomatöse Endokarditis durch Streptokokken.