title: Effect of vitamin E on some leucocytic parameters and functions in transported calves.
abstract: The objective of this investigation was to determine the effect of vitamin E administration on leucocyte parameters and some of their functions in transported calves. In the study 8 calves, aged approx. 10 days, divided into two groups, were used. 20 mg of tocopheryl-acetate per kg body weight were administered orally to each of the 4 experimental calves 24 hours before loading. The calves were transported by road for 3 hours. Blood samples collected before and after the transportation were examined for total and differential leucocyte counts, T-lymphocyte subpopulation, phagocytic activity, leucocyte migration, serum immunoglobulin levels, and for plasma vitamin E and cortisol levels. The animals showed a leucocytosis with neutrophilia and lymphopenia after transportation. The administration of vitamin E led to a decrease of cortisol level in 24 hours. There was no difference between groups in cortisol reaction due to transportation stress. Leucocyte migration has been less inhibited in the control group after unloading. A mild decline in phagocytic activity was observed 3 hours after transportation. Serum immunoglobulins were unaffected by both vitamin E administration and transportation. Vitamin E had no significant effect on leucocyte function and cortisol levels in present study.
authors.affiliation: University of Veterinary Medicine Kosice.
authors.forename: P
authors.initials: P
authors.lastname: Mudron
authors.forename: G
authors.initials: G
authors.lastname: Kovac
authors.forename: V
authors.initials: V
authors.lastname: Bajova
authors.forename: J
authors.initials: J
authors.lastname: Pistl
authors.forename: J
authors.initials: J
authors.lastname: Choma
authors.forename: P
authors.initials: P
authors.lastname: Bartko
authors.forename: H
authors.initials: H
authors.lastname: Scholz
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006854:Hydrocortisone / Q000097:blood; D007136:Immunoglobulins / Q000097:blood; D007958:Leukocyte Count; D007962:Leukocytes / Q000187:drug effects* / Q000276:immunology; D008297:Male; D013312:Stress, Physiological / Q000188:drug therapy / Q000276:immunology / Q000662:veterinary*; D014186:Transportation; D014810:Vitamin E / Q000097:blood / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D007136:Immunoglobulins; D014810:Vitamin E; D006854:Hydrocortisone