[VDT pulse magnetic field enhances teratogenic effect of ara-c in mice].
Impregnated NIH mice were irradiated 4 hrs daily on days 16th-17th of gestation with 15.6 kHz pulse magnetic field at 40 microT peak to peak. Significant enhancement of ara-c induced teratogenic potency by the magnetic field can be observed. The incidence of harelip fetuses bearing harelip and/or cleft palate was significantly higher in the combined exposure group, in which mice were exposed to the magnetic field and given an intraperitoneal injection of ara-c on the 9th day of gestation, than that of mice treated with ara-c alone.
Chiang
H
H
Microwave Institute, Zhejiang Medical University, Hangzhou.
D000014:Abnormalities, Drug-Induced; D000818:Animals; D002971:Cleft Lip / Q000209:etiology; D002972:Cleft Palate / Q000209:etiology; D016288:Computer Terminals; D003561:Cytarabine / Q000633:toxicity*; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure; D005260:Female; D051379:Mice; D011247:Pregnancy
D003561:Cytarabine