title: Human visceral leishmaniasis in Alpes-Maritimes, France: epidemiological characteristics for the period 1985-1992.
abstract: In 8 years (1985-1992), 65 cases of human visceral leishmaniasis (HVL) have been diagnosed in the department of Alpes-Maritimes, France, 56 of them having been infected locally. The annual frequency has increased from 3 cases in 1985 to 15 cases in 1992. There is a low rate of paediatric cases (29%) and a predominance of males among adult cases (85%). Since 1986, 19 cases of co-infection with Leishmania and human immunodeficiency virus 1 have been reported, corresponding to 40% of adult cases and to 30% of the total cases. The frequency of co-infections is stable at about 3 per annum. Isoenzymatic identification of the strains isolated from patients confirmed Leishmania infantum zymodeme MON-1 as responsible for most if not all HVL in the department of Alpes-Maritimes; 42 of the 44 strains isolated belonged to that zymodeme.
authors.affiliation: Faculté de Médecine, Université de Nice-Sophia Antipolis, France.
authors.forename: P
authors.initials: P
authors.lastname: Marty
authors.forename: Y
authors.initials: Y
authors.lastname: Le Fichoux
authors.forename: F
authors.initials: F
authors.lastname: Pratlong
authors.forename: M
authors.initials: M
authors.lastname: Gari-Toussaint
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications; D015497:HIV-1; D006801:Humans; D015994:Incidence; D007223:Infant; D018314:Leishmania infantum / Q000145:classification; D007898:Leishmaniasis, Visceral / Q000150:complications / Q000453:epidemiology* / Q000469:parasitology; D008297:Male