[The molecular cellular aspects in predicting the course of an acute myocardial infarct].
Ultra-high-frequency dielectrometry was used to determine the dielectric permeability of erythrocyte suspension cell membranes in 48 patients with acute myocardial infarction who were given agonists, antagonists, and modulators of the adenylate cyclase system. The study showed that the functional status of erythrocyte membranes changed correlating with the clinical course of the disease. Changes in this status were followed by complications of improvement. It was evidenced that the trend of a pathological process in coronary stress was associated with the functional status of erythrocyte membranes. Ultra-high-frequency dielectrometry is a sensitive method for evaluating the status of patients with myocardial infarction, controls the natural history of the diseases at the molecular level and to predict the development of complications.
Sviridova
E V
EV
Shchegoleva
T Iu
TIu
Bakhova
L K
LK
Vasil'ev
Iu M
IuM
D000262:Adenylyl Cyclases / Q000097:blood / Q000187:drug effects; D000328:Adult; D001782:Blood Donors; D002463:Cell Membrane Permeability / Q000187:drug effects; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000150:complications; D017202:Myocardial Ischemia / Q000097:blood / Q000150:complications; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D011379:Prognosis; D012008:Recurrence; D013997:Time Factors
D000262:Adenylyl Cyclases
Molekuliano-kletochnye aspekty prognozirovaniia techeniia ostrogo infarkta miokarda.