A neurochemically distinct third channel in the macaque dorsal lateral geniculate nucleus.
The primate visual system is often divided into two channels, designated M and P, whose signals are relayed to the cerebral cortex by neurons in the magnocellular and parvicellular layers of the dorsal lateral geniculate nucleus. We have identified a third population of geniculocortical neurons in the dorsal lateral geniculate nucleus of macaques, which is immunoreactive for the alpha subunit of type II calmodulin-dependent protein kinase. This large third population occupies interlaminar regions (intercalated layers) ventral to each principal layer. Retrograde labeling of kinase-immunoreactive cells from the primary visual cortex shows that they provide the geniculocortical input to cytochrome oxidase-rich puffs in layers II and III.
Hendry
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Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.
Yoshioka
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D000818:Animals; D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D005829:Geniculate Bodies / Q000166:cytology*; D007395:Interneurons / Q000166:cytology* / Q000201:enzymology; D008252:Macaca fascicularis; D008253:Macaca mulatta; D014793:Visual Cortex / Q000166:cytology*; D014795:Visual Pathways
D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2; D017871:Calcium-Calmodulin-Dependent Protein Kinases