title: Concentrations of calcium, magnesium, zinc and copper in relation to free fatty acids and cholesterol in serum of atherosclerotic men.
abstract: The concentrations of calcium, magnesium, zinc, copper, free fatty acids and total, HDL- and LDL-cholesterol in the sera of atherosclerotic men were determined. The subjects with femoral atherosclerosis were divided into two age groups: 35-59 years (N = 8, I) and 60-75 years (N = 8, II). The LDL-cholesterol concentration was increased in the elderly atherosclerotic group. Lower concentrations of calcium and magnesium, a higher concentration of copper and decreased Ca/Cu, Mg/Zn, Mg/Cu and Zn/Cu ratios were found in atherosclerosis I as compared to controls of the same age. High and positive correlations for Cu vs. total cholesterol and LDL-cholesterol (r > 0.89), but low correlation for Cu vs. HDL-cholesterol (r = 0.61) were calculated in atherosclerosis I, and negative correlations for free fatty acids vs. Ca and Mg (-r > 0.77) in atherosclerosis II.
authors.affiliation: Department of General Chemistry, K. Marcinkowski Academy of Medicine, Poznań, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Iskra
authors.forename: J
authors.initials: J
authors.lastname: Patelski
authors.forename: W
authors.initials: W
authors.lastname: Majewski
mesh_terms: D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000097:blood* / Q000503:physiopathology; D002118:Calcium / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003300:Copper / Q000097:blood*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006801:Humans; D008274:Magnesium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013054:Spectrophotometry, Atomic; D015032:Zinc / Q000097:blood*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D005230:Fatty Acids, Nonesterified; D003300:Copper; D008274:Magnesium; D015032:Zinc; D002118:Calcium