title: [Value of magnetic resonance in the staging of non-small-cell lung carcinoma].
abstract: In the last six years, 544 consecutive patients with nonsmall-cell bronchogenic carcinoma were studied with MRI. MR results were compared with surgical specimens and pathologic findings. Both TNM classification and ATS nodal mapping were considered. Local tumor extent (T parameter) was correctly identified in 67.2% of cases, understaged in 19.4% and overstaged in 13.4%. Lymph node metastases (N parameter) were adequately assessed in 55.5% of cases, understaged in 20.3% and overstaged in 24.2%. Considering two groups of patients, the first one with early stage disease (T1-T2, N0-N1) and the second one with advanced stages (T3-T4, N2-N3), MRI exhibited 84.6% overall accuracy, 57.3% sensitivity and 93.7% specificity for the T parameter and 72.3% accuracy, 65.2% sensitivity and 75.1% specificity for the N parameter. In conclusion, MRI did not provide the expected results in the staging of nonsmall-cell bronchogenic carcinoma, but improvement will probably be achieved with technological evolution.
authors.affiliation: Istituto Nazionale Tumori, Milano.
authors.forename: B
authors.initials: B
authors.lastname: Bozzini
authors.forename: J D
authors.initials: JD
authors.lastname: Tesoro-Tess
authors.forename: F
authors.initials: F
authors.lastname: Milani
authors.forename: A
authors.initials: A
authors.lastname: Amoruso
authors.forename: L
authors.initials: L
authors.lastname: Balzarini
authors.forename: E
authors.initials: E
authors.lastname: Ceglia
authors.forename: M
authors.initials: M
authors.lastname: Valente
authors.forename: E
authors.initials: E
authors.lastname: Turrini
authors.forename: R
authors.initials: R
authors.lastname: Musumeci
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D009367:Neoplasm Staging; D012680:Sensitivity and Specificity
vernacular_title: Valore della risonanza magnetica nella stadiazione del tumore polmonare non-microcitoma.