Oocytes from pachytene to dictyotene can easily be analysed in neonatal rodents.
We have investigated the dynamics of meiotic prophase I in neonatal ovaries from different wild rodent species, from a laboratory strain of Mus musculus and from Mus musculus x Mus spretus F1 hybrids. We found that almost all stages of prophase I were regularly present in neonatal ovaries from these species and that their transcriptional activity can be assessed by [3H]-uridine incorporation, indicating that postnatal analysis of meiotic chromosomes and synapsis may be conducted as an alternative to the investigation of foetal ovaries.
Singh
A P
AP
Institute of Human Genetics, Free University Berlin, Germany.
Maerzke
S
S
von Deimling
O
O
Raman
R
R
Sperling
K
K
Neitzel
H
H
D000818:Animals; D000831:Animals, Newborn; D003411:Arvicolinae; D002875:Chromosomes / Q000648:ultrastructure*; D006224:Cricetinae; D005260:Female; D006824:Hybridization, Genetic; D008540:Meiosis / Q000235:genetics*; D008647:Mesocricetus; D051379:Mice; D009115:Muridae; D009865:Oocytes / Q000648:ultrastructure*; D010053:Ovary / Q000648:ultrastructure; D012377:Rodentia / Q000235:genetics*; D013045:Species Specificity; D013573:Synaptonemal Complex / Q000235:genetics