title: Association between high concentration of antibodies to insulin and some diseases common in the elderly.
abstract: Antibodies to insulin (IA) were measured by graded hemagglutination in 164 patients and in 90 control subjects aged 18-65 years. The greatest prevalence of these antibodies was found in patients with the organic mental syndrome, of whom 70% (n = 110) had an antibody concentration above the normal 95th percentile. Among patients with diabetes, hypertension and cerebrovascular accidents, 42% had a high concentration of IA, while in all other geriatric patients (n = 21) the concentration of these antibodies was within the normal range.
authors.affiliation: Geriatric Departments, Nofim Senior Housing, Herzog Hospital, Jerusalem, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Wolk
authors.forename: M
authors.initials: M
authors.lastname: Kieselstein
authors.forename: R
authors.initials: R
authors.lastname: Hamburger
authors.forename: E
authors.initials: E
authors.lastname: Jaul
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000276:immunology*; D002561:Cerebrovascular Disorders / Q000276:immunology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000276:immunology; D006801:Humans; D006973:Hypertension / Q000276:immunology; D007330:Insulin Antibodies / Q000097:blood*; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000150:complications / Q000276:immunology
chemical_list: D007330:Insulin Antibodies