Reduced-system analysis of the effects of serotonin on a molluscan burster neuron.
The mathematical model described in Bertram (1993) is used to carry out a detailed examination of the manner in which the neurotransmitter serotonin modifies the voltage waveform generated endogenously by burster neuron R15 of Aplysia. This analysis makes use of a reduced system of equations, taking advantage of the slow rate of change of a pair of system variables relative to the others. Such analysis also yields information concerning the sensitivity of the neuron to brief+ synaptic perturbations.
Bertram
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Department of Mathematics and Supercomputer Computations Research Institute, Florida State University, Tallahassee 32306.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001048:Aplysia; D066298:In Vitro Techniques; D008433:Mathematics; D008959:Models, Neurological; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D009991:Oscillometry; D012701:Serotonin / Q000494:pharmacology*
D012701:Serotonin