Inhibitor binding to thrombin: x-ray crystallographic studies.
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Pharmaceutical Research Departments, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Hadváry
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D000595:Amino Acid Sequence; D000991:Antithrombins / Q000737:chemistry / Q000378:metabolism*; D001120:Arginine / Q000031:analogs & derivatives; D001665:Binding Sites; D018360:Crystallography, X-Ray; D004151:Dipeptides / Q000737:chemistry / Q000378:metabolism; D006629:Hirudins / Q000737:chemistry / Q000378:metabolism; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010875:Pipecolic Acids / Q000737:chemistry / Q000378:metabolism; D010880:Piperidines / Q000737:chemistry / Q000378:metabolism; D013449:Sulfonamides; D013917:Thrombin / Q000737:chemistry / Q000378:metabolism*
D000991:Antithrombins; D004151:Dipeptides; D006629:Hirudins; D010875:Pipecolic Acids; D010880:Piperidines; D013449:Sulfonamides; C038708:N(alpha)-(2-naphthylsulfonylglycyl)-4-amidinophenylalanine piperidide; D001120:Arginine; D013917:Thrombin; C031942:argatroban