Studies on antibiotic 230 as a molluscicide.
In the course of studying molluscicidal effects of microorganisms, a microorganism belonging to Streptomycetaceae, Streptomyces griseolus (Strain 230) was isolated from soil and a certain microbial ingredient proved to have a molluscicidal activity. The effective substance was named antibiotic 230. As a result of several investigations on the antibiotic, the following chemical features were made clear. The chemical substance was an indol-carbazole-heterocyclic compound, the molecular weight 446 and the molecular formula C28H26N4O3. The antibiotic demonstrated a molluscicidal effect against Oncomelania snails and their eggs both in the laboratory and in the field. The compound had a wide bacteriostasis spectrum and a slight toxicity to fish in addition to the above, but it was non-toxic to plants.
Chaosu
Y
Y
Hunan Institute of Parasitic Diseases, P.R. China.
Hu
D
D
Shi
M
M
Hu
G
G
D000818:Animals; D005399:Fishes; D007928:Lethal Dose 50; D008975:Molluscacides / Q000737:chemistry / Q000378:metabolism; D012908:Snails; D012988:Soil Microbiology; D013302:Streptomyces / Q000145:classification / Q000302:isolation & purification / Q000378:metabolism*
D008975:Molluscacides