title: Homologous recombination in fission yeast: absence of crossover interference and synaptonemal complex.
abstract: The study of homologous recombination in the fission yeast Schizosaccharomyces pombe has recently been extended to the cytological analysis of meiotic prophase. Unlike in most eukaryotes no tripartite SC structure is detectable, but linear elements resembling axial cores of other eukaryotes are retained. They may be indispensable for meiotic recombination and proper chromosome segregation in meiosis I. In addition fission yeast shows interesting features of chromosome organization in vegetative and meiotic cells: Centromeres and telomeres cluster and associate with the spindle pole body. The special properties of fission yeast meiosis correlate with the absence of crossover interference in meiotic recombination. These findings are discussed. In addition homologous recombination in fission yeast is reviewed briefly.
authors.affiliation: Institute of General Microbiology, University of Bern, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Kohli
authors.forename: J
authors.initials: J
authors.lastname: Bähler
mesh_terms: D002875:Chromosomes / Q000648:ultrastructure; D008540:Meiosis; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics; D012568:Schizosaccharomyces / Q000235:genetics* / Q000254:growth & development / Q000648:ultrastructure; D013573:Synaptonemal Complex / Q000502:physiology*