title: Postoperative complications and prognostic indicators in dogs and cats with septic peritonitis: 23 cases (1989-1992).
abstract: Medical records of 21 dogs and 2 cats treated for septic peritonitis were reviewed. Animals were between 1 and 12 years old, (mean, 6.5 years) and weighed between 6 and 51.4 kg (mean, 22.7 kg). Overall, 13 animals survived and were discharged from the hospital. Immediately after surgical correction of the underlying cause of peritonitis, most animals were tachycardic (mean heart rate, 148 beats/min; range, 80 to 204 beats/min), and many were hypotensive (mean arterial pressure, 84.4 mm of Hg; range, 44 to 156 mm of Hg). Hypotension was attributed to sepsis and hypovolemia secondary to extensive loss of fluid into the peritoneal cavity. Survivors did not differ from nonsurvivors with regard to mean arterial pressure immediately after surgery, and in most animals, hypotension could be corrected by IV administration of fluids. Three animals died after failing to respond to fluid treatment, despite concurrent administration of inotropic or pressor agents. Mean rate for crystalloid fluid administration was 12.8 ml/kg of body weight/h (range, 5 to 23.5 ml/kg/h) during the first 24 hours after surgery. Six of 23 animals had low urine output for a short time after surgery, but urine output increased when fluids were administered. Hypoalbuminemia developed in all animals (mean serum albumin concentration, 1.17 g/dl; range, 0.6 to 2.3 g/dl), and peripheral edema developed in 13. Neither lowest mean serum albumin concentration nor fluid administration rate was significantly different between animals that developed peripheral edema and those that did not. Fluid administration rates were significantly higher in nonsurvivors (15 ml/kg/h; range, 5.5 to 23.5 ml/kg/h) than in survivors (11 ml/kg/h; range, 5 to 17.5 ml/kg/h).(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
authors.forename: L G
authors.initials: LG
authors.lastname: King
mesh_terms: D000818:Animals; D001424:Bacterial Infections / Q000601:surgery / Q000662:veterinary*; D001798:Blood Proteins / Q000032:analysis; D002371:Cat Diseases / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D002415:Cats; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000662:veterinary; D004283:Dog Diseases / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D004285:Dogs; D004322:Drainage / Q000662:veterinary; D004487:Edema / Q000209:etiology / Q000662:veterinary; D005260:Female; D005440:Fluid Therapy / Q000662:veterinary; D006439:Hemodynamics; D007022:Hypotension / Q000209:etiology / Q000628:therapy / Q000662:veterinary; D008297:Male; D010195:Pancreatitis / Q000209:etiology / Q000662:veterinary; D010538:Peritonitis / Q000601:surgery / Q000662:veterinary*; D011183:Postoperative Complications / Q000628:therapy / Q000662:veterinary*; D011379:Prognosis; D012140:Respiratory Tract Diseases / Q000209:etiology / Q000662:veterinary; D012189:Retrospective Studies
chemical_list: D001798:Blood Proteins