title: Balloon valvuloplasty for valvular pulmonary stenosis in children over 6 months of age: initial results and long-term follow-up.
abstract: Between 1984 and December 1990 balloon valvuloplasty for valvular pulmonary stenosis was planned and performed in 92 children over 6 months of age (range 0.8-17.9 years). Valvuloplasty decreased the invasively determined peak systolic gradient from 61 +/- 34 (mean +/- SD) to 27 +/- 20 mmHg (P < 0.0001). At follow-up cardiac catheterization, performed in 22 patients after 13 +/- 5 months, the gradient was 22 +/- 23 mmHg (ns). Initially the continuous wave Doppler gradient decreased from 61 +/- 23 to 26 +/- 12 mmHg (P < 0.0001). It then remained unchanged both at early follow-up after 0.6 +/- 0.3 years, being 23 +/- 12 mmHg, and at long-term follow-up after 3 +/- 1.7 years (21 +/- 10 mmHg, ns). In the 41 patients treated before the end of 1986 the residual continuous wave Doppler gradient at long-term follow-up after 5.1 +/- 0.8 years was 21 +/- 10 mmHg. Mild pulmonary regurgitation was present in 77% of the patients at early follow-up and in 83% at the last follow-up. Right ventricular hypertrophy on the electrocardiogram was present in 83% of the children before valvuloplasty. At early follow-up it had decreased to 44% with a further decrease to 24% at the last follow-up. Comparison of patients with initial invasive systolic gradients greater and smaller than 50 mmHg revealed no differences between either group with regard to the continuous wave Doppler gradient at last follow-up, the incidence of pulmonary regurgitation and the occurrence of significant complications.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Paediatrics, Sophia Children's Hospital/University Hospital Rotterdam, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Witsenburg
authors.forename: M
authors.initials: M
authors.lastname: Talsma
authors.forename: J
authors.initials: J
authors.lastname: Rohmer
authors.forename: J
authors.initials: J
authors.lastname: Hess
mesh_terms: D000293:Adolescent; D002404:Catheterization / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D011665:Pulmonary Valve Insufficiency / Q000209:etiology; D011666:Pulmonary Valve Stenosis / Q000000981:diagnostic imaging / Q000628:therapy*