title: Live attenuated vaccine vectors.
abstract: Several different live attenuated vaccine vectors currently are under development. These vaccines are composed of living viruses or bacteria that are innocuous to the host but can replicate in host tissues and induce immune responses. The genes encoding foreign antigens can be inserted into these vectors to produce multivalent vaccines that promise to induce immunity to more than one target disease after the administration of a single dose of vaccine.
authors.affiliation: Harvard Medical School.
authors.forename: J J
authors.initials: JJ
authors.lastname: Mekalanos
mesh_terms: D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D015195:Drug Design; D004341:Drug Evaluation; D006801:Humans; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology*; D017778:Vaccines, Combined / Q000008:administration & dosage / Q000276:immunology*; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D001428:Bacterial Vaccines; D014613:Vaccines, Attenuated; D017778:Vaccines, Combined; D014765:Viral Vaccines