title: Effects of pulsed magnetic fields in the therapy of osteoporosis induced by ovariectomy in the rat.
abstract: This paper presents preliminary results on the effects of pulsed electromagnetic fields (EMF) in the therapy of post menopausal osteoporosis induced by ovariectomy in female rats aged ten months. In particular, the effects of the intensity of pulsed EMF applied at constant frequency has been studied. Magnetic fields pulsed at 50 Hz were used having a positive sinusoidal wave form with a maximum intensity of 30 and 70 Gauss. Treatment lasting one hour per day for 4 months showed that the pulsed EMF with 30 Gauss of maximum intensity are able to slow down the bone mass loss, keeping it within some 10%; with pulsed EMF with 70 Gauss of maximum intensity, instead, no significant bone mass loss was observed.
authors.affiliation: Institute Orthopaedic Rizzoli, University of Bologna.
authors.forename: A
authors.initials: A
authors.lastname: Zati
authors.forename: S
authors.initials: S
authors.lastname: Gnudi
authors.forename: R
authors.initials: R
authors.lastname: Mongiorgi
authors.forename: R
authors.initials: R
authors.lastname: Giardino
authors.forename: M
authors.initials: M
authors.lastname: Fini
authors.forename: G
authors.initials: G
authors.lastname: Valdrè
authors.forename: I
authors.initials: I
authors.lastname: Galliani
authors.forename: A M
authors.initials: AM
authors.lastname: Montagnani
mesh_terms: D000818:Animals; D015519:Bone Density; D005260:Female; D006801:Humans; D008280:Magnetics / Q000627:therapeutic use*; D010012:Osteogenesis; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control*; D010052:Ovariectomy / Q000009:adverse effects*; D051381:Rats; D017207:Rats, Sprague-Dawley