Absorption of iron from ferric hydroxypyranone complexes.
The absorption of 59Fe from preparations of FeSO4 and the ferric hydroxypyranone complexes maltol and ethyl maltol was studied by whole-body counting in normal subjects and patients with Fe deficiency. Fe in the Fe3+ complexes was in general absorbed almost as well as Fe2+. It is concluded that the absorption of Fe3+ from hydroxypyranone complexes is much greater than that from simple Fe3+ salts; this may prove an efficient and less toxic form of Fe for the treatment of deficiency.
Maxton
D G
DG
Gastrointestinal Laboratory, Rayne Institute, St Thomas' Hospital, London.
Thompson
R P
RP
Hider
R C
RC
D000328:Adult; D000368:Aged; D000747:Anemia, Hypochromic / Q000188:drug therapy; D005260:Female; D005290:Ferric Compounds / Q000008:administration & dosage* / Q000378:metabolism; D005296:Ferrous Compounds / Q000008:administration & dosage / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology*; D007501:Iron / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011753:Pyrones / Q000008:administration & dosage* / Q000378:metabolism; D014915:Whole-Body Counting
D005290:Ferric Compounds; D005296:Ferrous Compounds; D011753:Pyrones; D007501:Iron; C062088:ferric maltol