Clinical and prognostic investigations on M2/t(8;21) acute nonlymphocytic leukemia.
Clinical and prognostic investigations were conducted in 46 cases of M2/t(8;21) leukemia and 29 cases of M2/NN patients. Results showed that most patients with M2/t(8;21) were young males with higher incidence of extramedullary infiltrations. Complete remission rate was higher but with earlier relapse. The prognosis of patients with M2/t(8;21) with loss of one sexual chromosome was poor.
Cheng
F J
FJ
Research Institute of Hematology, Tongji Medical University, Wuhan.
Yang
A D
AD
Fei
H B
HB
Tian
H
H
D000328:Adult; D002869:Chromosome Aberrations; D002881:Chromosomes, Human, Pair 12; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D011379:Prognosis; D014178:Translocation, Genetic; D014998:Y Chromosome