Magnesium effect on the membrane potential of smooth muscle cells of human placental chorionic vessels.
The effects of magnesium ions were studied in human placental chorionic vessel smooth muscle cells (from arteries and veins), particularly on the membrane potential Um. Um was classically recorded with microelectrodes. Magnesium ions, in the range 1-10 mM, depolarize the membrane of the smooth muscle cells (the effect is more important in arteries than in veins). Magnesium ions influence the membrane potential directly and regulate the viability of the K+ channels.
Bara
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University P.M. Curie, Paris, France.
Guiet-Bara
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A
D001158:Arteries / Q000187:drug effects; D002824:Chorionic Villi / Q000098:blood supply* / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008274:Magnesium / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects*; D014680:Veins / Q000187:drug effects
D008274:Magnesium