title: Second-generation benzodiazepine CCK-B antagonists. Development of subnanomolar analogs with selectivity and water solubility.
authors.affiliation: Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486.
authors.forename: M G
authors.initials: MG
authors.lastname: Bock
authors.forename: R M
authors.initials: RM
authors.lastname: DiPardo
authors.forename: E C
authors.initials: EC
authors.lastname: Mellin
authors.forename: R C
authors.initials: RC
authors.lastname: Newton
authors.forename: D F
authors.initials: DF
authors.lastname: Veber
authors.forename: S B
authors.initials: SB
authors.lastname: Freedman
authors.forename: A J
authors.initials: AJ
authors.lastname: Smith
authors.forename: S
authors.initials: S
authors.lastname: Patel
authors.forename: J A
authors.initials: JA
authors.lastname: Kemp
authors.forename: G R
authors.initials: GR
authors.lastname: Marshall
mesh_terms: D000818:Animals; D001569:Benzodiazepines / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology*; D006801:Humans; D008954:Models, Biological; D011949:Receptors, Cholecystokinin / Q000037:antagonists & inhibitors* / Q000378:metabolism; D012995:Solubility
chemical_list: D011949:Receptors, Cholecystokinin; D001569:Benzodiazepines