title: An outbreak of tuberculosis in a captive herd of Arabian oryx (Oryx leucoryx): management.
abstract: An outbreak of tuberculosis due to Mycobacterium bovis in a herd of Arabian oryx (Oryx leucoryx) was managed by sanitary and medical measures. The sanitary measures included the isolation of infected animals, the monitoring of animals with a range of diagnostic tests and the hand-rearing of the progeny of the infected herd. All the infected oryx were treated with a mixture of isoniazid at 10 mg/kg bodyweight, ethambutol hydrochloride at 15 mg/kg bodyweight and rifampicin at 10 mg/kg bodyweight administered daily in the drinking water. These measures resulted in the cessation of mortalities, a decrease in the numbers of moderate and high risk animals and the production of tuberculosis-free animals for reintroduction into the wild.
authors.affiliation: National Wildlife Research Center (National Commission for Wildlife Conservation and Development, Taif, Saudi Arabia.
authors.forename: A
authors.initials: A
authors.lastname: Greth
authors.forename: J R
authors.initials: JR
authors.lastname: Flamand
authors.forename: A
authors.initials: A
authors.lastname: Delhomme
mesh_terms: D000818:Animals; D000866:Antelopes; D004196:Disease Outbreaks / Q000662:veterinary*; D004977:Ethambutol / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D007538:Isoniazid / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D011247:Pregnancy; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D012529:Saudi Arabia / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000453:epidemiology / Q000662:veterinary*
chemical_list: D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin