title: A comparison of two systems for assessing cerebral venous oxyhaemoglobin saturation during cardiopulmonary bypass in humans.
abstract: The Somanetics Invos 3,100 cerebral oximeter is a new noninvasive device which measures the regional oxygen saturation of haemoglobin within the cerebral microvasculature by infrared spectroscopy. It was used in nine patients undergoing elective cardiac surgery and its results were compared with measurements of jugular venous bulb saturations obtained by the Oximetrix Opticath oximetry system. The index value of jugular venous bulb saturation was obtained by analysis of jugular bulb blood in an Il282 cooximeter. The cerebral oximeter was less accurate and precise (standard deviation of difference 14.1%) than the Oximetrix system (standard deviation of the difference 2.65%) and also demonstrated a systematic error in bias unrelated to cerebral perfusion pressure. The cerebral oximeter may therefore be less useful than jugular venous bulb saturation in the clinical management of patients undergoing cardiopulmonary bypass.
authors.affiliation: Department of Anaesthesia, Harefield Hospital, Middlesex.
authors.forename: R
authors.initials: R
authors.lastname: Brown
authors.forename: G
authors.initials: G
authors.lastname: Wright
authors.forename: D
authors.initials: D
authors.lastname: Royston
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D002315:Cardiopulmonary Bypass; D002550:Cerebral Veins; D006801:Humans; D008875:Middle Aged; D010092:Oximetry / Q000295:instrumentation*; D010108:Oxyhemoglobins / Q000378:metabolism*
chemical_list: D010108:Oxyhemoglobins