Factors associated with abruptio placentae in preterm deliveries.
OBJECTIVE
To evaluate risk factors associated with occurrence of abruptio placentae in preterm deliveries.


METHODS
Risk factors were evaluated in 55 consecutive index cases of abruptio placentae and 726 control patients delivered between 24-36 weeks' gestation.


RESULTS
In logistic regression analysis abruptio placentae was associated with a low number of antenatal visits, smoking in pregnancy, hypertension, intravenous drug abuse and a history of recent abdominal trauma. Among hypertensive disorders of pregnancy, preeclampsia superimposed on chronic hypertension was associated with the highest risk of premature placental separation. Finally, there was a significant trend relating duration of premature rupture of membranes with abruptio placentae (chi-square for trend = 3.93, p = 0.047).


CONCLUSIONS
Several risk factors seem strongly associated with abruptio placentae in preterm deliveries; the presence of these risk factors should dictate intensive surveillance.
Spinillo
A
A
Department of Obstetrics and Gynecology, University of Pavia, IRCCS Policlinico S. Matteo, P. Ie Golgi, Italy.
Capuzzo
E
E
Colonna
L
L
Solerte
L
L
Nicola
S
S
Guaschino
S
S
D000037:Abruptio Placentae / Q000150:complications / Q000453:epidemiology / Q000209:etiology; D000428:Alcohol Drinking; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005322:Premature Rupture of Fetal Membranes / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000150:complications; D011225:Pre-Eclampsia / Q000150:complications; D011247:Pregnancy; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects