Isolation, structural identification and biological activity of two metabolites produced by Penicillium olsonii Bainier and Sartory.
From the culture broth of a fungus, two metabolites have been isolated: bis(2-ethylhexyl)phthalate (DEHP) precedently isolated from Streptomyces sp. and 2-(4-hydroxyphenyl)-2-oxoacetaldehyde oxime (PHBA) here reported as a natural compound in the (E)-s-cis configuration. The producing organism was identified as a strain of Penicillium olsonii. Culture growth and chemical identification are discussed in the present work.
Amade
P
P
INSERM, U. 303, La Darse, Villefranche-sur-Mer, France.
Mallea
M
M
Bouaïcha
N
N
D004051:Diethylhexyl Phthalate / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010091:Oximes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010407:Penicillium / Q000378:metabolism*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013237:Stereoisomerism
C086650:2-(4-hydroxyphenyl)-2-oxoacetaldehyde oxime; D010091:Oximes; D010636:Phenols; D004051:Diethylhexyl Phthalate