[Functional study of the heart valve apparatus by 2-dimensional Doppler echocardiography in rats with experimental endocarditis caused by Coxsackie B3 viruses].
Eleven neonatal cotton rats were infected with Coxsackie B3 viruses, 9 animals served as controls. The course of the disease was followed for 44 to 154 days. Electro- and phonocardiography, two-dimensional Doppler echocardiography, morphological and histological studies were performed in the experiment. All the histologically examined infected rats were found to develop myocarditis, whereas 75% of the animals had valvulitis. The total number of the afflicted values was 10, out of them the mitral, tricuspid, and pulmonary trunk valves accounted for 40, 40, and 20%, respectively. Doppler echocardiography revealed organic mitral and tricuspid insufficiencies in the outcome of valvulitis induced by Coxsackie B3 viruses due to the impairment of valvular cusp.
Polubentsova
E I
EI
Lavrova
I K
IK
Stulova
M A
MA
Prokhorova
I A
IA
D000818:Animals; D000831:Animals, Newborn; D003384:Coxsackievirus Infections / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D015150:Echocardiography, Doppler / Q000295:instrumentation; D004562:Electrocardiography; D004696:Endocarditis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology*; D029822:Enterovirus B, Human; D006349:Heart Valve Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology; D006351:Heart Valves / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D016205:Sigmodontinae; D013997:Time Factors
Issledovanie funktsional'nogo sostoianiia klapannogo apparata serdtsa metodom dvukhmernoĭ doppler-ékhokardiografii u krys pri éksperimental'nom éndokardite, vyzvannom virusami Koksaki B3.