title: Screening-detected and symptomatic ductal carcinoma in situ: mammographic features with pathologic correlation.
abstract: OBJECTIVE
  To compare the mammographic and pathologic features of screening-detected and symptomatic ductal carcinoma in situ (DCIS).
  
  
  METHODS
  The mammographic and pathologic features of 54 screening-detected and 77 symptomatic cases of DCIS were compared. Patients were aged 30-76 years (mean, 58 years).
  
  
  RESULTS
  Diffuse involvement was seen in 10 patients (13%) with symptoms but in none of the screening-detected group (P < .05). The disease was radiologically more extensive in the symptomatic group. Calcifications in the symptomatic group (n = 48) were less likely to have a ductal distribution than those in the screening-detected group (n = 48) (30 [63%] vs 40 [83%], respectively; P < .05). At histologic examination in some cases, the symptomatic group (n = 76) included eight (11%) patients with cribriform-micropapillary, large-cell tumors (P < .05) and less comedocarcinoma (20 [26%] vs 23 [45%], respectively; P < .05) compared with the screening-detected group (n = 51).
  
  
  CONCLUSIONS
  The results show differences in the radiologic and pathologic features of screening-detected and symptomatic DCIS.
authors.affiliation: Department of Radiology, Nottingham City Hospital, England.
authors.forename: A J
authors.initials: AJ
authors.lastname: Evans
authors.forename: S
authors.initials: S
authors.lastname: Pinder
authors.forename: I O
authors.initials: IO
authors.lastname: Ellis
authors.forename: M
authors.initials: M
authors.lastname: Sibbering
authors.forename: C W
authors.initials: CW
authors.lastname: Elston
authors.forename: D N
authors.initials: DN
authors.lastname: Poller
authors.forename: R
authors.initials: R
authors.lastname: Wilson
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged