title: [The preparation of 99mTc-NGA instant lyophilized kit for hepatic imaging].
abstract: The preparation of one-step kit for the 99mTc labelled galactosyl-neo-glycoalbumin (NGA) using SnCl2 reduced method was reported in this paper. We developed a method of quality control and established the optimum scheme of technetium labelling on the basis of exploring the effects of varied labelled conditions on radiochemical purity. Our data indicates : (a) the kit is sterile, pyrogen-free and no toxic effects; (b) the operation is simple and fast; (c) its period of validity lasts no less than 3 months; (d) the radiochemical purity > 95%; (e) the stability of 99mTc-NGA in vitro > 4 hours; (f) the results of animal imaging and clinical probation are satisfactory.
authors.forename: C
authors.initials: C
authors.lastname: Guan
authors.forename: Q
authors.initials: Q
authors.lastname: Chen
authors.forename: T
authors.initials: T
authors.lastname: Tan
mesh_terms: D000418:Albumins; D000818:Animals; D037263:Asialoglycoprotein Receptor; D002352:Carrier Proteins / Q000378:metabolism; D002645:Chickens; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging*; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging; D015609:Organotechnetium Compounds; D011817:Rabbits; D011877:Radionuclide Imaging; D011933:Reagent Kits, Diagnostic; D012709:Serum Albumin
chemical_list: D000418:Albumins; D037263:Asialoglycoprotein Receptor; D002352:Carrier Proteins; D015609:Organotechnetium Compounds; D011933:Reagent Kits, Diagnostic; D012709:Serum Albumin; C027122:hepatic sialoglycoprotein receptor; C036586:technetium Tc 99m neogalactoalbumin