[The effect of exogenous gangliosides on the formation in rats of instrumental movements with tactile control].
The process of learning and memorization of instrumental reaching movements with pressure on an operandum by a preferable forepaw were studied in white rats after ganglioside injections. The coursed of learning in control and ganglioside injected animals were shown to be alike while some ganglioside treated rats demonstrated increased motor activity. After a 5-week interval animals of both groups were able to perform quick reaching movements, but the storage of ability to push the operandum during the defined time was revealed only in ganglioside injected group. It may be considered that the ganglioside injections support the long-term storage of learned movements with tactile control.
Zhuravin
I A
IA
Nalivaeva
N N
NN
Dubrovskaia
N M
NM
D000818:Animals; D003216:Conditioning, Operant / Q000187:drug effects* / Q000502:physiology; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D007839:Functional Laterality / Q000187:drug effects / Q000502:physiology; D005732:Gangliosides / Q000494:pharmacology*; D008297:Male; D009043:Motor Activity / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D013997:Time Factors; D014110:Touch / Q000187:drug effects* / Q000502:physiology
D005732:Gangliosides
Vliianie ékzogennykh gangliozidov na formirovanie u krys instrumental'nykh dvizheniĭ s taktil'nym kontrolem.