Immunohistological and immuno-electron microscopic localization of fibronectin in chicken bone marrow.
Fibronectin (FN) was immunolocated in chicken bone marrow with the PAP-technique by light and electron microscopy. A pre-embedding method was employed for immunolabelling the specimen for electron microscopy. Blood vessels and lining cells of capillaries and sinusoids were labelled for FN. Monocytes, intrasinusoidal macrophages, and stromal elements in the extrasinusoidal compartment. The distribution of FN in the chicken bone marrow supports the assumption that FN facilitates extravascular haematopoiesis, especially migratory processes, whereas its contribution to intravascular haematopoiesis seems less likely and needs further investigation.
Bube
A
A
Institut für Veterinär-Pathologie, Justus-Liebig Universität Giessen, Germany.
Weiss
E
E
D000818:Animals; D001853:Bone Marrow / Q000737:chemistry* / Q000648:ultrastructure; D002645:Chickens / Q000502:physiology*; D005353:Fibronectins / Q000032:analysis*; D006410:Hematopoiesis; D007150:Immunohistochemistry; D016253:Microscopy, Immunoelectron / Q000662:veterinary
D005353:Fibronectins