[The functional dynamics of the system of immunity in rats during adaptation to single and fractionated exposures to low doses of external gamma irradiation].
The content of serum corticosterone so as immunological and nonspecific reactivity in rats exposed to single or fractionated gamma-radiation (0.35 Gy) were studied during 1 month. It has been revealed that corticosterone level, dynamics of absolute amount of leucocytes, lymphocytes, Rc-receptor-bearing cells in blood, relative content of FcR(+)-cells in bone marrow, spleen and peripheral lymph nodes of irradiated animals depend on the scheme of irradiation. Single irradiation didn't significantly influence natural and antibody-dependent killer cells activity and basal chemiluminescence level of polymorphonuclear cells, while the fractionated irradiation in equal dose induced considerable fluctuations of these parameters. The direction and intensity of the disturbances depend on the time after irradiation.
Sambur
M B
MB
Mel'nikov
O F
OF
Timchenko
S V
SV
Timchenko
M D
MD
D000222:Adaptation, Physiological / Q000276:immunology / Q000528:radiation effects*; D000818:Animals; D003345:Corticosterone / Q000097:blood / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D007107:Immune System / Q000276:immunology / Q000528:radiation effects*; D007111:Immunity, Cellular / Q000528:radiation effects; D007113:Immunity, Innate / Q000528:radiation effects; D008297:Male; D051381:Rats; D017452:Receptors, IgG / Q000528:radiation effects; D013997:Time Factors
D017452:Receptors, IgG; D003345:Corticosterone
Dinamika sostoianiia sistemy immuniteta krys v protsesse adaptatsii k odnokratnomu i fraktsionirovannomu vozdeĭstviiu malykh doz vneshnego gamma-oblucheniia.