Minoxidil overdose.
A 52-year-old man ingested 60 ml of 2 percent topical minoxidil solution resulting in severe hypotension and tachycardia. He was resuscitated with intravenously administered crystalloid solution and treated with intravenously administered dopamine, resulting in a partial hemodynamic improvement. Further treatment with intravenously administered phenylephrine infusion resulted in resolution of hypotension. The patient suffered a non-Q-wave myocardial infarction as a result of the ingestion. The toxicity of this increasingly common preparation is profound.
MacMillan
A R
AR
Holy Cross Hospital-Calgary District Hospital Group, Alberta, Canada.
Warshawski
F J
FJ
Steinberg
R A
RA
D062787:Drug Overdose; D006801:Humans; D008297:Male; D008875:Middle Aged; D008914:Minoxidil / Q000506:poisoning*; D011041:Poisoning / Q000628:therapy
D008914:Minoxidil