title: The relationship between aminoaciduria and plasma hemoglobin levels.
abstract: Investigations in newborns, children and young adults have revealed an inverse proportion between aminoaciduria and plasma hemoglobin (Hb) levels. Values above normal were recorded for alanine, leucine, valine, phenylalanine and glutamic acid, correlating proportionally with their increased blood levels, and preceding or being concomitant with the decrease of plasma Hb, both during the first 20 months of life and in young adults. The return to near normal values of aminoaciduria occurred generally only after an early treatment with minerals, vitamins and trace elements (Supradyn), activators of the enzymes involved in the amino acid metabolism. After treatment, the Hb levels also became almost normal. An early re-equilibration of the amino acid metabolism can prevent the risk of developing, at the adult age, certain anemias and other diseases (rachitism, mental handicap, urinary infections, conjunctivitis, stomatitis, a.o.). The correlation factor was r = 0.964 and the differences between the data recorded in patients and in controls were statistically significant (p < 0.01).
authors.affiliation: Center of Diabetes, Bucharest.
authors.forename: T
authors.initials: T
authors.lastname: Mogoş
authors.forename: C
authors.initials: C
authors.lastname: Popescu
authors.forename: A
authors.initials: A
authors.lastname: Dumitrescu
authors.forename: I
authors.initials: I
authors.lastname: Tănase
authors.forename: I
authors.initials: I
authors.lastname: Mincu
mesh_terms: D000592:Amino Acid Metabolism, Inborn Errors / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology / Q000652:urine; D000596:Amino Acids / Q000187:drug effects / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D006454:Hemoglobins / Q000032:analysis* / Q000187:drug effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008903:Minerals / Q000627:therapeutic use; D009930:Organic Chemicals; D012383:Romania / Q000453:epidemiology; D013997:Time Factors; D014131:Trace Elements / Q000627:therapeutic use; D014815:Vitamins / Q000627:therapeutic use
chemical_list: D000596:Amino Acids; D004338:Drug Combinations; D006454:Hemoglobins; D008903:Minerals; D009930:Organic Chemicals; C086404:Supradyn; D014131:Trace Elements; D014815:Vitamins