[The antibacterial action of new hydrazide derivatives].
New derivatives of 4-aminobenzoic and 4-chlorine-2-hydroxybenzoic acids hydrazides were synthesized by the condensation reaction of these hydrazides with aldehydes and ketones, derivatives containing in their molecule azometine and hydrazone groups. The obtained products are potentially bioactive. The study of their "in vitro" biological activity was performed on some pathogenic germs, both gram-positive and gram-negative. The results show that the tested substances are more active towards the gram-positive germs.
Ciugureanu
C
C
Faculté de Chemie, Université Al. I. Cuza Iassy.
Ungureanu
M
M
Grosu
G
G
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D006835:Hydrazones / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D006835:Hydrazones
Sur l'action antibacterienne de quelques nouveaux dérivés de l'hydrazide.