[Concentrations of ethanol and ethanol metabolites and symptoms of acute alcohol-intoxicated patients].
Five patients who presented to an emergency room and did not have other injury and disease with acute alcohol intoxication were analyzed about blood and urine ethanol, acetaldehyde, acetate and acetone levels. The average concentrations of ethanol, acetaldehyde, acetate and acetone in blood were 37.0 mM (1.7 mg/ml), 18 microM, 1.00 mM and 18 microM, respectively and the concentrations in urine were 50.8 mM (2.3 mg/ml), 37 microM, 0.79 mM and 47 microM, respectively. Clinical symptoms were concerned with both ethanol concentration and concentrations of ethanol metabolites. Their symptoms of acute alcohol-intoxicated patients were caused by the ethanol concentrations which was less than the levels reported in early studies.
Kitazawa
M
M
Department of Legal Medicine, Nihon University School of Medicine, Tokyo, Japan.
Tsukamoto
S
S
Kanegae
T
T
Tie
J
J
Kaneko
Y
Y
Shiratori
R
R
Oshida
S
S
D000079:Acetaldehyde / Q000032:analysis; D000085:Acetates / Q000032:analysis; D000096:Acetone / Q000032:analysis; D000328:Adult; D000435:Alcoholic Intoxication / Q000378:metabolism*; D000431:Ethanol / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged
D000085:Acetates; D000096:Acetone; D000431:Ethanol; D000079:Acetaldehyde