title: Pancreatic exocrine function and necrotising enterocolitis.
abstract: Pancreatic protease deficiency may be an aetiological factor in enteritis necroticans, a disease sharing some features of necrotising enterocolitis (NEC). Using faecal chymotrypsin measurement we have prospectively studied pancreatic exocrine function in infants at risk of NEC. No significant difference was found comparing those infants who subsequently developed NEC and those who did not.
authors.affiliation: Academic Unit of Paediatrics and Child Health, University of Leeds, UK.
authors.forename: C M
authors.initials: CM
authors.lastname: Wood
authors.forename: P
authors.initials: P
authors.lastname: MacKay
authors.forename: K D
authors.initials: KD
authors.lastname: Willis
authors.forename: G A
authors.initials: GA
authors.lastname: Brown
authors.forename: J W
authors.initials: JW
authors.lastname: Puntis
mesh_terms: D002918:Chymotrypsin / Q000032:analysis*; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology* / Q000503:physiopathology; D005243:Feces / Q000737:chemistry; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000503:physiopathology*; D010179:Pancreas / Q000503:physiopathology*; D011446:Prospective Studies; D012307:Risk Factors
chemical_list: D002918:Chymotrypsin