Identification of chemicals for testing in the rodent cancer bioassay.
A recently developed method was used to identify the structural moieties that are not represented among the chemicals tested in the U.S. National Toxicology Program rodent cancer bioassay. Inclusion of those chemicals in the bioassay would increase the informational content of rodent cancer assay data base.
Takihi
N
N
Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261.
Rosenkranz
H S
HS
Klopman
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G
D000818:Animals; D001681:Biological Assay; D002273:Carcinogens / Q000737:chemistry / Q000633:toxicity; D051379:Mice; D009316:National Institutes of Health (U.S.); D009374:Neoplasms, Experimental / Q000139:chemically induced*; D051381:Rats; D012376:Rodent Diseases / Q000139:chemically induced*; D013329:Structure-Activity Relationship; D014481:United States
D002273:Carcinogens