title: Lack of effect of quinidine on divalent mineral absorption from the reticulorumen of sheep.
abstract: The effects of quinidine on divalent mineral absorption were studied using normal and high potassium intraruminal buffers with the in vivo isolated washed rumen technique. A concentration of 1 mmol litre-1 quinidine in the intraruminal buffer decreased the absorption rates of Na+ and C1- from the rumen but had no significant effect on the absorption rates of Mg2+, Ca2+ and K+. Prolonged oral administration of quinidine had no significant effect on the absorption of any of these ions from either a normal or a high potassium ruminal solution.
authors.affiliation: Department of Biochemistry, University of Wales, Aberystwyth.
authors.forename: K
authors.initials: K
authors.lastname: Dua
authors.forename: A D
authors.initials: AD
authors.lastname: Care
mesh_terms: D000818:Animals; D002413:Cations, Divalent / Q000378:metabolism; D007408:Intestinal Absorption / Q000187:drug effects*; D008903:Minerals / Q000378:metabolism*; D011802:Quinidine / Q000494:pharmacology*; D012417:Rumen / Q000187:drug effects* / Q000378:metabolism; D012756:Sheep / Q000378:metabolism*
chemical_list: D002413:Cations, Divalent; D008903:Minerals; D011802:Quinidine