title: Dynamics of brain activation during picture naming.
abstract: The cerebral representation of language, deduced from observing patients with brain lesions and from stimulations and recordings performed during brain surgery, has been further clarified by recent positron emission tomography and functional magnetic resonance imaging measurements. We now expand this static view into the dynamics of cortical activation using the accurate spatiotemporal resolution of whole-head magnetoencephalography. During picture naming, the conversion from visual to symbolic representation progressed bilaterally from the occipital visual cortex towards temporal and frontal lobes. Overt naming elicited the most widespread cortical activation. Some language-related sites also reacted, though more weakly or after a longer delay, during covert naming and even passive viewing.
authors.affiliation: Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland.
authors.forename: R
authors.initials: R
authors.lastname: Salmelin
authors.forename: R
authors.initials: R
authors.lastname: Hari
authors.forename: O V
authors.initials: OV
authors.lastname: Lounasmaa
authors.forename: M
authors.initials: M
authors.lastname: Sams
mesh_terms: D000328:Adult; D001931:Brain Mapping; D005260:Female; D005625:Frontal Lobe / Q000502:physiology; D006801:Humans; D007802:Language; D015225:Magnetoencephalography; D008297:Male; D015398:Signal Transduction; D013702:Temporal Lobe / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*