title: Pontine infarction in acute posterior multifocal placoid pigment epitheliopathy.
abstract: In a patient with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), a pontine infarction occurred about 6 months after the ophthalmological manifestation. We report the first case with histopathologically proven vasculitis shown by muscle biopsy and the first positron emission tomographic documentation in APMPPE. The ophthalmological and cerebral symptoms responded well to steroid treatment. Long-term immunosuppression (e.g. azathioprine 1-2 mg/kg) seems to decrease the risk of recurrent systemic vasculitis.
authors.affiliation: Neurologische Klinik, Städtischen Krankenhauses Leverkusen, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Bewermeyer
authors.forename: G
authors.initials: G
authors.lastname: Nelles
authors.forename: M
authors.initials: M
authors.lastname: Huber
authors.forename: C
authors.initials: C
authors.lastname: Althaus
authors.forename: E
authors.initials: E
authors.lastname: Neuen-Jacob
authors.forename: J
authors.initials: J
authors.lastname: Assheuer
mesh_terms: D000208:Acute Disease; D000328:Adult; D001160:Arterioles; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000209:etiology*; D015862:Choroid Diseases / Q000150:complications*; D003236:Conjunctivitis, Viral / Q000150:complications; D005451:Fluorescein Angiography; D006801:Humans; D007511:Ischemia / Q000209:etiology*; D008297:Male; D010857:Pigment Epithelium of Eye / Q000098:blood supply*; D011149:Pons / Q000098:blood supply* / Q000000981:diagnostic imaging; D014055:Tomography, Emission-Computed; D014657:Vasculitis / Q000150:complications*