Thyroid cancer in a case with the Alagille syndrome.
A 19-year-old woman with the Alagille syndrome developed papillary thyroid carcinoma with lung metastasis. She was diagnosed as having Alagille syndrome at the age of 8. Following total thyroidectomy and lymph nodes dissection, iodine-131 therapy was conducted for local and distant metastases. This is the first report of a case of thyroid cancer accompanying Alagille syndrome.
Kato
Z
Z
Department of Pediatrics, Gifu University School of Medicine, Japan.
Asano
J
J
Kato
T
T
Yamaguchi
S
S
Kondo
N
N
Orii
T
T
D000328:Adult; D016738:Alagille Syndrome / Q000150:complications*; D002291:Carcinoma, Papillary / Q000150:complications* / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D013964:Thyroid Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D013965:Thyroidectomy