title: MR imaging of flow through tortuous vessels: a numerical simulation.
abstract: A novel computer simulation technique is presented that allows the calculation of images from Magnetic Resonance Angiography (MRA) studies of blood flow in realistic curving and branching two-dimensional vessel geometries. Fluid dynamic calculations provide flow streamlines through curved or branching vessels. MR simulations generate images for specific MR pulse sequence parameters. Simulations of steady flow in carotid bifurcation and carotid siphon geometries as imaged by a standard, flow-compensated, spoiled gradient echo sequence illustrate the major features seen in clinical time of flight MRA studies. The simulations provide insight into a number of artifacts encountered in MRA such as displacement artifacts, signal pile-up, truncation artifacts, and intravoxel phase dispersion.
authors.affiliation: Department of Radiology, University of California at San Francisco.
authors.forename: R
authors.initials: R
authors.lastname: van Tyen
authors.forename: D
authors.initials: D
authors.lastname: Saloner
authors.forename: L D
authors.initials: LD
authors.lastname: Jou
authors.forename: S
authors.initials: S
authors.lastname: Berger
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001809:Blood Viscosity / Q000502:physiology; D002339:Carotid Arteries / Q000033:anatomy & histology / Q000502:physiology*; D017536:Carotid Artery, Common / Q000502:physiology; D002342:Carotid Artery, External / Q000502:physiology; D002343:Carotid Artery, Internal / Q000502:physiology; D003198:Computer Simulation; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008280:Magnetics; D008955:Models, Cardiovascular; D012039:Regional Blood Flow / Q000502:physiology; D012212:Rheology