title: [An evaluation of the role of paired loading tests in selecting the long-term drug therapy for patients with stable angina].
abstract: The examination of 208 patients with stable exercise-induced angina has demonstrated that the long-term (12 weeks and 12 months) antianginal effect can be predicted with a high accuracy from the results of acute pair exercise test using the drugs. The negative result of the test with verapamil is not informative due to the accumulation of its antianginal effect when the agent is used long. The long-term antianginal effect of nitrosorbide is determined not only by positive pair exercise test, but mainly by its dosage regimen during a day. The fact that half the patients who took labetalol for a long time developed tolerance to its anginal effect casts some suspicion on the advisability of its administration in stable angina. Lipid peroxidation as a mechanism of platelet aggregability regulation.
authors.forename: L G
authors.initials: LG
authors.lastname: Voronkov
authors.forename: N F
authors.initials: NF
authors.lastname: Sokolov
authors.forename: M L
authors.initials: ML
authors.lastname: Sharaeva
authors.forename: V A
authors.initials: VA
authors.lastname: Kuts'
authors.forename: A N
authors.initials: AN
authors.lastname: Lomakovskiĭ
mesh_terms: D000787:Angina Pectoris / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D002317:Cardiovascular Agents / Q000008:administration & dosage; D005080:Exercise Test / Q000187:drug effects* / Q000706:statistics & numerical data; D017079:Exercise Tolerance / Q000187:drug effects; D006801:Humans; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D005082:Physical Exertion / Q000187:drug effects*; D011237:Predictive Value of Tests; D011379:Prognosis; D013997:Time Factors
chemical_list: D002317:Cardiovascular Agents
vernacular_title: Otsenka roli parnykh nagruzochnykh testov v podbore dlitel'noĭ medikamentoznoĭ terapii bol'nym so stabil'noĭ stenokardieĭ.