title: [Spinocellular cancer in lichen sclerosus et atrophicus of the vulva].
abstract: We report on a 78-year-old woman with a 47-year-history of lichen sclerosus et atrophicus of the vulva on which squamous cell carcinoma developed. The lesion started as a small nodule that increased gradually in size and became eroded. The tumour and the inguinal lymph nodes on both sides were excised. Physical examination, chest X-ray and sonography of the abdomen 15 months later showed no local recurrence or distant metastases. Lichen sclerosus et atrophicus of the vulva should be considered a possible precancerous condition.
authors.affiliation: Universitätsklinik für Haut- und Geschlechtskrankheiten, Heinrich-Heine-Unviersität Düsseldorf.
authors.forename: U
authors.initials: U
authors.lastname: Hofmann
authors.forename: M
authors.initials: M
authors.lastname: Megahed
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002455:Cell Division / Q000502:physiology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005260:Female; D006801:Humans; D017512:Lichenoid Eruptions / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D014844:Vulva / Q000473:pathology; D007724:Vulvar Lichen Sclerosus / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology*
vernacular_title: Spinozelluläres Karzinom auf einem Lichen sclerosus et atrophicus der Vulva.