[An evaluation of the effect of a bark extract from the cashew (Anacardium occidentale L.) on infection by Leishmania (Viannia) braziliensis].
This paper presents an evaluation of the therapeutic effect of an hydroalcoholic extract of A. occidentale L. bark against Leishmania (Viannia) brasiliensis. The extract showed high activity in the in vitro model against the promastigotes of this species. However in the in vivo model no curative activity was observed.
França
F
F
Núcleo de Medicina Tropical e Nutrição, Universidade de Brasília, DF.
Cuba
C A
CA
Moreira
E A
EA
Miguel
O
O
Almeida
M
M
das Virgens
M de L
Mde L
Marsden
P D
PD
D000818:Animals; D001938:Brazil; D006224:Cricetinae; D004353:Drug Evaluation, Preclinical; D007892:Leishmania braziliensis / Q000187:drug effects; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D013997:Time Factors; D014197:Trees
D010936:Plant Extracts
Avaliação do efeito do extrato de casca de cajueiro-branco (Anacardium occidentale L.) sobre a infecção por Leishmania (Viannia) brasiliensis.