The development of airways obstruction in sarcoidosis among smokers and non-smokers.
The prevalence of respiratory function abnormalities was studied in 32 patients with pulmonary sarcoidosis, 16 (50%) of whom were smokers. Airflow obstruction was found at presentation in one non-smoker and developed in four more during the course of follow-up. Similar airflow obstruction was present in six smoking patients and developed in four patients subsequently. Airways obstruction was a common physiological defect even in non-smokers, though smokers had more frequent airflow obstruction and developed a worse defect.
Coates
R
R
Chest Clinic, St Mary's Hospital, Portsmouth, U.K.
Neville
E
E
D000328:Adult; D000402:Airway Obstruction / Q000209:etiology*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000503:physiopathology; D012907:Smoking / Q000009:adverse effects* / Q000503:physiopathology; D014797:Vital Capacity