title: Diagnostics of malignant lymphomas with ultrasound guided 1.2 mm biopsy-gun.
abstract: In a retrospective analysis of 129 ultrasound-guided biopsy-gun biopsies (USGB) from patients with known or suspected malignant lymphoma, a histopathological diagnosis was obtained in 101 (78%) instances and no further procedures for histological verification were required. In the 28 cases with initially non-diagnostic results, 14 new USGBs were performed and a diagnosis was obtained in 11. Thus, a total success rate of 87% was achieved. The correct diagnosis was confirmed with either surgery, autopsy, or radiological or clinical follow-up (median 40 months). The diagnoses were categorised as Hodgkin's disease and high-grade or low-grade non-Hodgkin's lymphoma. Further subtyping of the lymphoma was possible in a few cases only. Immunohistochemistry was utilised only in a minor proportion of the cases (25/129), but refined the diagnosis in several instances. The biopsy-gun method was safe and minor adverse effects were seen in two patients only.
authors.affiliation: Department of Oncology, University of Uppsala, Akademiska sjukhuset, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Kälkner
authors.forename: S
authors.initials: S
authors.lastname: Rehn
authors.forename: T
authors.initials: T
authors.lastname: Andersson
authors.forename: A
authors.initials: A
authors.lastname: Elvin
authors.forename: H
authors.initials: H
authors.lastname: Hagberg
authors.forename: P G
authors.initials: PG
authors.lastname: Lindgren
authors.forename: C
authors.initials: C
authors.lastname: Sundström
authors.forename: B
authors.initials: B
authors.lastname: Glimelius
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D005260:Female; D006689:Hodgkin Disease / Q000000981:diagnostic imaging; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014463:Ultrasonography / Q000009:adverse effects