title: Urinary enzyme concentrations in the owl monkey (Aotus nancymae).
abstract: The activity of three urinary enzymes, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and N-acetyl-beta-D-glucosaminidase (NAG), was evaluated in 71 adult owl monkeys. Fifty-six animals had normal renal function, while 15 had evidence of renal dysfunction. Urinary enzyme: urinary creatinine ratios (UE: UCr) were also determined. The activity for NAG was similar to that of other species, while ALP and AST were higher. Regression analyses revealed that urinary enzymes and UE:UCr were significantly correlated (P < or = 0.0001) with indices of renal damage and could identify active renal disease.
authors.affiliation: Battelle Pacific NW Laboratories, Richland, WA 99352.
authors.forename: R E
authors.initials: RE
authors.lastname: Weller
authors.forename: C A
authors.initials: CA
authors.lastname: Málaga
authors.forename: R L
authors.initials: RL
authors.lastname: Buschbom
authors.forename: H A
authors.initials: HA
authors.lastname: Ragan
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine*; D000469:Alkaline Phosphatase / Q000652:urine*; D000818:Animals; D016645:Aotidae / Q000652:urine*; D001219:Aspartate Aminotransferases / Q000652:urine*; D003404:Creatinine / Q000097:blood / Q000652:urine; D004573:Electrolytes / Q000097:blood / Q000652:urine; D007674:Kidney Diseases / Q000175:diagnosis / Q000652:urine / Q000662:veterinary*; D016778:Malaria, Falciparum / Q000652:urine; D008992:Monkey Diseases; D011507:Proteinuria; D012016:Reference Values; D012044:Regression Analysis
chemical_list: D004573:Electrolytes; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase; D000118:Acetylglucosaminidase