A possible survival advantage in adults with acute leukemia receiving ABO-identical platelet transfusions.
In a small cohort of leukemic patients participating in a randomized trial of ABO-identical vs. ABO-unmatched platelet transfusions, a statistically significant decrease in remission duration and increase in mortality were observed in patients receiving ABO-unmatched platelet transfusions. This difference was unexplained by previously described prognostic factors for remission duration and survival. Further study of this association is warranted.
Heal
J M
JM
Department of Pathology, University of Rochester Medical Center, NY 14642.
Kenmotsu
N
N
Rowe
J M
JM
Blumberg
N
N
D000017:ABO Blood-Group System; D000208:Acute Disease; D000328:Adult; D006801:Humans; D007938:Leukemia / Q000453:epidemiology / Q000628:therapy*; D008875:Middle Aged; D017713:Platelet Transfusion / Q000379:methods; D016019:Survival Analysis
D000017:ABO Blood-Group System