[The antiarrhythmic activity of glycolysis and Krebs cycle intermediates in early occlusion and reperfusion arrhythmias in rats].
Acute experiments on unconscious rats have demonstrated that fructose-1,6-diphosphate, phosphoenolpyruvate and malate of sodium produced a marked antiarrhythmic activity in acute occlusive and reperfusion arrhythmias, prevented the development of ventricular fibrillation and tachycardias, considerably reduced the duration of arrhythmia paroxysms, but they were ineffective in ventricular extrasystole.
Balashov
V P
VP
Balykova
L A
LA
Sedova
D G
DG
Belova
L A
LA
Sernov
L N
LN
Kostin
Ia V
IaV
D000208:Acute Disease; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000209:etiology; D002952:Citric Acid Cycle; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D005260:Female; D006019:Glycolysis; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000150:complications / Q000188:drug therapy*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D000889:Anti-Arrhythmia Agents
Issledovanie protivoaritmicheskoĭ aktivnosti nekotorykh intermediatov glikoliza i tsikla Krebsa pri rannikh okkliuzionnykh i reperfuzionnykh aritmiiakh u krys.