title: Effect of thyroid hormone treatment on thyromegaly in children and adolescents with Hashimoto disease.
abstract: The effect of thyroid hormone treatment on thyromegaly was evaluated in 69 patients < or = 18 years of age with goitrous Hashimoto disease. Changes in goiter size were related to pretreatment thyroid function (serum thyroxine and thyrotropin concentrations). We found that only hypothyroid patients had a clear diminution of their thyromegaly when given thyroid hormone.
authors.affiliation: Department of Pediatrics, Mayo Clinic, Rochester, Minnesota 55905.
authors.forename: K I
authors.initials: KI
authors.lastname: Rother
authors.forename: D
authors.initials: D
authors.lastname: Zimmerman
authors.forename: W F
authors.initials: WF
authors.lastname: Schwenk
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006042:Goiter / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000209:etiology; D008297:Male; D012189:Retrospective Studies; D013963:Thyroid Hormones / Q000627:therapeutic use*; D013967:Thyroiditis, Autoimmune / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013963:Thyroid Hormones; D013972:Thyrotropin; D013974:Thyroxine