Sequencing of a cDNA encoding the human fast-twitch skeletal muscle isoform of troponin I.
A cDNA encoding the human fast-twitch skeletal muscle isoform of troponin I (TnIfast) has been sequenced. This cDNA is 701 base pairs in length, and encodes a protein of 182 amino acids. TnIfast is the last of the three known human TnI isoforms to be sequenced. Comparison of the deduced human TnIfast protein sequence with a variety of troponin I isoforms from other species has revealed a high degree of cross-species sequence conservation between TnIfast proteins.
Zhu
L
L
Department of Biological Chemistry, University of Maryland School of Medicine, Baltimore 21201.
Perez-Alvarado
G
G
Wade
R
R
D000595:Amino Acid Sequence; D001483:Base Sequence; D018076:DNA, Complementary / Q000737:chemistry* / Q000302:isolation & purification; D005333:Fetus / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D009132:Muscles / Q000378:metabolism*; D016415:Sequence Alignment; D014336:Troponin / Q000235:genetics*; D019210:Troponin I
D018076:DNA, Complementary; D014336:Troponin; D019210:Troponin I