The wily ways of a parasite: induction of actin assembly by Listeria.
The intracellular pathogen Listeria has a spectacular mode of transport within and between host cells. By inducing host cell actin to assemble from its surface, the bacterium forms a tail composed of many short, crossbridged actin filaments. With this tail Listeria is propelled across the cytoplasm like a comet streaking across the sky. Here we discuss the antics of Listeria and some of the bacterial genes instrumental in maintaining it in the host.
Tilney
L G
LG
Dept of Biology, University of Pennsylvania, Philadelphia 19104-6018.
Tilney
M S
MS
D000199:Actins / Q000378:metabolism*; D005798:Genes, Bacterial / Q000502:physiology; D008087:Listeria / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D008264:Macrophages / Q000382:microbiology*
D000199:Actins