Cytochrome P-450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: opportunities and limitations.
Yang
C S
CS
Laboratory for Cancer Research, College of Pharmacy, Rutgers University, Piscataway, New Jersey 08855.
Smith
T J
TJ
Hong
J Y
JY
D000498:Allyl Compounds; D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D001711:Biotransformation; D002273:Carcinogens / Q000378:metabolism* / Q000633:toxicity*; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D017879:Isothiocyanates / Q000494:pharmacology; D008175:Lung Neoplasms / Q000139:chemically induced / Q000209:etiology / Q000517:prevention & control; D008862:Microsomes, Liver / Q000201:enzymology; D012907:Smoking; D013440:Sulfides / Q000494:pharmacology*
D000498:Allyl Compounds; D016588:Anticarcinogenic Agents; D002273:Carcinogens; D065607:Cytochrome P-450 Enzyme Inhibitors; D017879:Isothiocyanates; D013440:Sulfides; C038491:allyl sulfide; D003577:Cytochrome P-450 Enzyme System