[A decrease in the damaging action of gamma irradiation on human lymphocytes by postradiation treatment with the preparation MDI].
The effect of MDI, the agent of plant origin, on the cell cycle and the number of micronuclei in human lymphocytes after gamma-irradiation has been studied. It has been found that the treatment of lymphocytes with MDI stimulates DNA synthesis and reduces the delay of irradiated cells in (G2 + M) phase. Moreover post-irradiation cell treatment with MDI reduces the number of damaged cells.
Sobol'
K V
KV
Koliubaeva
S N
SN
Komar
V E
VE
D002478:Cells, Cultured / Q000737:chemistry / Q000187:drug effects / Q000528:radiation effects; D004247:DNA / Q000032:analysis / Q000187:drug effects / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005434:Flow Cytometry; D005720:Gamma Rays; D006801:Humans; D007399:Interphase / Q000187:drug effects / Q000528:radiation effects; D008214:Lymphocytes / Q000737:chemistry / Q000187:drug effects* / Q000528:radiation effects*; D015162:Micronucleus Tests; D010936:Plant Extracts; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D013997:Time Factors
C086712:MDI radiation protective agent; D010936:Plant Extracts; D011837:Radiation-Protective Agents; D004247:DNA
Snizhenie povrezhdaiushchego deĭstviia gamma-oblucheniia na limfotsity cheloveka pri postluchevoĭ obrabotke preparatom MDI.