title: Effect of various post-brushing activities on salivary fluoride concentration after toothbrushing with a sodium fluoride dentifrice.
abstract: The study consisted of eight experiments, divided into three series, aimed at investigating the effect on the salivary fluoride (F) concentration of three post-brushing regimes: (1) rinsing once or twice with water, (2) rinsing either with a slurry of the toothpaste foam and water or with an 0.05% NaF solution, or a single NaF mouthrinse with no prior brushing, and (3) chewing and drinking ('eating') for 2 min. Brushing was done with 1.5 g of an 0.32% NaF dentifrice. The concentration of F in whole saliva was determined in 15 subjects at various time points up to 45 min after completing each experimental procedure. Results showed that the initial (0 min post-brushing) F concentration in saliva decreased about 1-2 times after a single, and 4-5 times after a double post-brushing water-rinse, as compared with no rinsing at all (p < 0.001). Brushing followed by a mouthrinse with an 0.05% NaF solution elevated the F concentration more than brushing alone (p < 0.001). Rinsing with the slurry of toothpaste foam and water gave only a somewhat (but not significantly) lower concentration of F in saliva than just rinsing with the 0.05% NaF solution. Eating immediately after brushing reduced the salivary F level about 12-15 times (p < 0.001) compared with brushing alone.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Cariology, Faculty of Odontology, University of Göteborg, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Sjögren
authors.forename: D
authors.initials: D
authors.lastname: Birkhed
mesh_terms: D000328:Adult; D003802:Dentifrices; D004326:Drinking; D004435:Eating; D005260:Female; D005459:Fluorides / Q000032:analysis* / Q000493:pharmacokinetics; D006801:Humans; D008297:Male; D008409:Mastication; D008875:Middle Aged; D009067:Mouthwashes; D012463:Saliva / Q000737:chemistry*; D012969:Sodium Fluoride / Q000008:administration & dosage*; D014099:Toothbrushing / Q000379:methods; D014867:Water
chemical_list: D003802:Dentifrices; D009067:Mouthwashes; D014867:Water; D012969:Sodium Fluoride; D005459:Fluorides