title: Two end-to-side neurorrhaphies and nerve graft with removal of the epineural sheath: experimental study in rats.
abstract: We have studied a new type of end-to-side nerve repair in rats. The healthy (donor) nerve was not divided but an epineural window was created. In our experiment, a nerve graft bridged the tibial nerve to the distal end of the divided peroneal nerve. Electrophysiological studies showed electrical impulses conducted through both end-to-side nerve junctions. Histological studies demonstrated axons leaving the lateral surface of the healthy (donor) nerve. Based on these observations, we suggest that end-to-side neurorrhaphy from a healthy nerve may bridge a neural deficit.
authors.affiliation: Faculdade de Medicina, Universidade Estadual Paulista/UNESP, São Paulo, Brazil.
authors.forename: F
authors.initials: F
authors.lastname: Viterbo
authors.forename: J C
authors.initials: JC
authors.lastname: Trindade
authors.forename: K
authors.initials: K
authors.lastname: Hoshino
authors.forename: A
authors.initials: A
authors.lastname: Mazzoni
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001369:Axons; D006614:Hindlimb; D008297:Male; D009121:Muscle Denervation; D009132:Muscles / Q000166:cytology / Q000294:innervation; D009412:Nerve Fibers; D009416:Nerve Regeneration; D016067:Nerve Transfer; D010543:Peroneal Nerve / Q000502:physiology / Q000601:surgery*; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000502:physiology; D013537:Sutures; D013979:Tibial Nerve / Q000502:physiology / Q000601:surgery*