title: [Determination of apparent pharmacokinetic parameters of shengfu injection by acute mortality of mice].
abstract: Apparent pharmacokinetic parameters of Shengfu injection, a first-aid traditional Chinese medicine, were determined by acute mortality of animals. The results suggested that the pharmacokinetics of Shengfu injection accords with the two compartment open model, and t1/2 alpha = 0.063h, t1/2 beta = 2.70h. The process of distribution was quite rapid, and the process of elimination was slow.
authors.forename: W
authors.initials: W
authors.lastname: Gong
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
authors.forename: S
authors.initials: S
authors.lastname: Hou
authors.forename: G
authors.initials: G
authors.lastname: Liao
mesh_terms: D000818:Animals; D004365:Drugs, Chinese Herbal / Q000493:pharmacokinetics* / Q000633:toxicity; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D005894:Panax; D010946:Plants, Medicinal
chemical_list: D004365:Drugs, Chinese Herbal