title: Hypophyseal non-Hodgkin's lymphoma presenting with clinical panhypopituitarism successfully treated with chemotherapy.
abstract: A patient is described with a testicular Non-Hodgkin's Lymphoma (NHL) presenting with panhypopituitarism caused by a hypophyseal localization. A 67Gallium scintigraphy showed avid uptake in the hypophyseal region. Obviously 67Gallium could reach the tumor, by the intravenous route, which was the reason to treat the patient with intravenous chemotherapy. A complete remission was induced, which seems to be lasting (+25 months). As far as we know this is the first report of panhypopituitarism caused by a hypophyseal NHL in the hypophysis and successfully treated by intravenous chemotherapy.
authors.affiliation: Department of Hematology, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: A R
authors.initials: AR
authors.lastname: Jonkhoff
authors.forename: P C
authors.initials: PC
authors.lastname: Huijgens
authors.forename: W O
authors.initials: WO
authors.lastname: Schreuder
authors.forename: G J
authors.initials: GJ
authors.lastname: Teule
authors.forename: J J
authors.initials: JJ
authors.lastname: Heimans
mesh_terms: D000368:Aged; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D011877:Radionuclide Imaging