[Multiple antibiotic resistance in Haemophilus influenzae related to serogroup B].
OBJECTIVE
To study the association between multiply antibiotic resistance in Haemophilus influenzae and H. influenzae type B, and to describe levels and patterns of antibiotic resistance.


METHODS
Statistical analysis and susceptibility of 231 H. influenzae strains (52 type B and 179 non-typable ) isolated consecutively from pediatric patients.


RESULTS
Resistance levels for type B and non-typable strains were: Ampicillin, 55.3% vs 28.8%; Chloramphenicol, 44.7% vs 9.2%; Ampicillin plus chloramphenicol, 40.4% vs 7.6%; cotrimoxazole, 89.3% vs 67.4%; resistance to six or more antibiotics, 36.0% vs 3.8%.


CONCLUSIONS
Multiply antibiotic resistance in H. influenzae is strongly associated with type B strains, with age of 4 or younger, and with isolation from CSF or blood. Resistance is sustained over long periods of time.
Campos
J
J
Servicio de Microbiología, Hospital Sant Joan de Déu, Barcelona.
Seuba
T
T
Trujillo
G
G
Rodríguez
A
A
Roca
J
J
D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D006192:Haemophilus Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D006193:Haemophilus influenzae / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D012703:Serotyping; D013030:Spain / Q000453:epidemiology
Resistencia de Haemophilus influenzae a múltiples antibióticos asociada al serogrupo B.