The female longevity phenomenon. Hypotheses on some molecular and cell biology aspects.
The most relevant theories on the sex-dependent longevity at population level are critically re-examined in the light of the knowledge available today on the aging process at cellular and molecular level. The aim of this perspective is to help in the understanding of the cellular and molecular bases of longevity and to indicate the most suitable biological models of investigation.
Magnani
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M
Istituto di Chimica Biologica G. Fornaini, Università degli Studi di Urbino, Italy.
Accorsi
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D000818:Animals; D003432:Cross-Linking Reagents; D005260:Female; D005609:Free Radicals; D006801:Humans; D008136:Longevity / Q000235:genetics / Q000502:physiology; D008297:Male; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D012727:Sex Characteristics
D003432:Cross-Linking Reagents; D005609:Free Radicals