title: Localized fibrous tumor of the pleura. Report of two cases with immunohistochemical study.
abstract: The light microscopy and immunohistochemical findings of two new cases of localized fibrous tumor of the pleura are reported. Both cases remained asymptomatic. One of them was incidentally found in a 69 year-old male during a thoracotomy for adenocarcinoma of the lung. The other was discovered in a 51 year-old woman in the course of a routine chest X-ray. Bundles of tightly packed benign fibroblasts within a collagen-rich stroma were the histologic hallmark. Bizarre cells and prominent sclerosis were extensive features in the first case. Only vimentin showed diffuse positive immunostaining in proliferating cells. Our results support the fibroblastic origin proposed for this lesion.
authors.affiliation: Department of Pathology, Hospital de Basurto, Basque Country University, Bilbao, Spain.
authors.forename: J I
authors.initials: JI
authors.lastname: Lopez
authors.forename: A
authors.initials: A
authors.lastname: Ferández-Larrinoa
authors.forename: E
authors.initials: E
authors.lastname: Pereda
authors.forename: C
authors.initials: C
authors.lastname: Ereño
mesh_terms: D000230:Adenocarcinoma / Q000150:complications; D000368:Aged; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008654:Mesothelioma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology