Expression of CDw12 and CD17 cell surface antigens on leukemic cells from patients with blood malignancies.
In 67 cases of newly diagnosed blood malignancies, NonT-ALL, T-ALL, AMLL, AML, CML, CLL, HCL, PLL, MDS, B splenic lymphoma, AUL, as well as in 9 cell lines (U937, HEL, Jurkat, HL60, UHKT2, KG1, Raji, K562, REH), we have analysed the expression and distribution of 2 relatively incompletely studied antigenic markers from the CD nomenclature: CDw12 and CD17, individually and in combination with well characterized ones. We present our data for the usefulness of these molecules in immunodiagnosis of leukemias and lymphomas.
Marinov
J
J
Institute of Haematology and Blood Transfusion, Praha.
Koubek
K
K
Starý
J
J
D015703:Antigens, CD / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D014408:Biomarkers, Tumor; D001853:Bone Marrow / Q000473:pathology; D006402:Hematologic Diseases / Q000378:metabolism; D006801:Humans; D016130:Immunophenotyping; D007938:Leukemia / Q000276:immunology / Q000473:pathology*; D008223:Lymphoma / Q000276:immunology / Q000473:pathology*; D014407:Tumor Cells, Cultured
D015703:Antigens, CD; D000954:Antigens, Surface; D014408:Biomarkers, Tumor