title: [Infectious toxic shock in generalized rotaviral infection in newborns].
abstract: The possibility of the rotavirus infection generalization, the course of which was complicated by the infectious toxic shock and disseminated intravascular coagulation syndrome as a cause of death of three newborns is shown for the first time. Etiology of the disease was established by electron microscopy, immunoenzymatic and immunofluorescent methods in the faeces, blood and postmortem material. The manifestations of giant cell metamorphosis not only in the intestine but also in the pia mater, kidneys, liver, lungs characteristic of RNA-viral infections indirectly confirmed the presence of viremia. Combination of rota- and respiratory syncytial viral infections made a pathologic process more severe with the development of necrotising enterocolitis, perforative serous peritonitis, intraabdominal hemorrhage.
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Anisimova
authors.forename: A V
authors.initials: AV
authors.lastname: Tsinzerling
authors.forename: I V
authors.initials: IV
authors.lastname: Dziubluk
mesh_terms: D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D018357:Respiratory Syncytial Virus Infections / Q000150:complications / Q000473:pathology; D012400:Rotavirus Infections / Q000150:complications* / Q000473:pathology; D012772:Shock, Septic / Q000209:etiology* / Q000473:pathology; D014781:Viscera / Q000473:pathology
vernacular_title: Infektsionno-toksicheskiĭ shok pri generalizovannoĭ rotavirusnoĭ infektsii u novorozhdennykh.