title: [Acetylcholine and effectiveness of oxidative phosphorylation in isolated rat hepatocytes].
abstract: It is shown that ADP and DNP does not intensify the respiration rate in hepatocytes of rats obtained by means of trypsin or EDTA. The same cells obtained using collagenase, phosphorylate added ADP and increase the respiration rate after DNP addition. Acetylcholine added to the cell suspension in a dose of 5 x 4 x 10(-8) M) increases the efficiency of oxidative phosphorylation. The scheme of neurotransmitter regulation of intensity of respiration and efficiency of oxidative phosphorylation on the cell level is suggested.
authors.forename: S K
authors.initials: SK
authors.lastname: Gordiĭ
authors.forename: I V
authors.initials: IV
authors.lastname: Shostakovs'ka
authors.forename: M M
authors.initials: MM
authors.lastname: Doliba
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology*; D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D011756:Diphosphates / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000166:cytology / Q000187:drug effects*; D008297:Male; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D051381:Rats
chemical_list: D011756:Diphosphates; D000244:Adenosine Diphosphate; D000109:Acetylcholine
vernacular_title: Atsetylkholin i efektyvnist' okysnoho fosforyliuvannia izol'ovanykh hepatotsytiv shchuriv..