Detection of varicella-zoster virus DNA in conjunctivas of patients with herpes zoster.
Detection of varicella-zoster virus (VZV) DNA was carried out in the conjunctivas of 18 patients with herpes zoster by polymerase chain reaction. The rate of VZV DNA detection in conjunctivas was 3/4 in herpes zoster ophthalmicus associated with eruption on the dorsum nasi, 2/5 in herpes zoster ophthalmicus without eruption on the dorsum nasi, 1/2 in herpes zoster with eruption on the cheek and lower jaw, 1/2 in generalized herpes zoster and 0/5 in herpes zoster associated with eruption on the trunk or extremities, respectively. The reason for the detection of VZV DNA in conjunctivas is discussed.
Tamura
T
T
Department of Dermatology, School of Medicine, Kinki University, Osaka, Japan.
Yoshida
M
M
Tezuka
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001483:Base Sequence; D003228:Conjunctiva / Q000382:microbiology*; D017931:DNA Primers; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006562:Herpes Zoster / Q000175:diagnosis / Q000382:microbiology; D006563:Herpes Zoster Ophthalmicus / Q000175:diagnosis / Q000382:microbiology*; D014645:Herpesvirus 3, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D012867:Skin / Q000382:microbiology
D017931:DNA Primers; D004279:DNA, Viral