title: Morning bright light therapy for sleep and behavior disorders in elderly patients with dementia.
abstract: Fourteen inpatients with dementia showing sleep and behavior disorders (average age = 75 years), and 10 control elderly people (average age = 75 years) were carefully observed for 2 months. Four weeks of morning light therapy markedly improved sleep and behavior disorders in the dementia group. The measurement of sleep time and the serum melatonin values suggests that sleep and behavior disorders in the dementia group are related to decreases in the amplitude of the sleep-wake rhythm and decreases in the levels of melatonin secretions. Morning light therapy significantly increased total and nocturnal sleep time and significantly decreased daytime sleep time. These results indicate that morning bright light is a powerful synchronizer that can normalize disturbed sleep and substantially reduce the frequency of behavior disorders in elderly people with dementia.
authors.affiliation: Department of Neuropsychiatry, Akita University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Mishima
authors.forename: M
authors.initials: M
authors.lastname: Okawa
authors.forename: Y
authors.initials: Y
authors.lastname: Hishikawa
authors.forename: S
authors.initials: S
authors.lastname: Hozumi
authors.forename: H
authors.initials: H
authors.lastname: Hori
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000503:physiopathology / Q000628:therapy*; D001143:Arousal / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology*; D015161:Dementia, Multi-Infarct / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008550:Melatonin / Q000097:blood; D008875:Middle Aged; D010789:Phototherapy; D007319:Sleep Initiation and Maintenance Disorders / Q000503:physiopathology / Q000628:therapy; D012893:Sleep Wake Disorders / Q000503:physiopathology / Q000628:therapy*; D012919:Social Behavior
chemical_list: D008550:Melatonin