[The characteristics of catecholamine excretion in parkinsonism patients in effective treatment and therapeutic resistance].
Catecholamines excretion has been analyzed in 36 patients suffering from parkinsonism and in 30 normal subjects. Curable patients demonstrated the same proportion of epinephrine and norepinephrine/DOPA excretion as normal subjects did. In resistant to treatment subjects and in unlikely curable the above coefficients were significantly larger. It is suggested that enhanced activity of peripheral sympathoadrenal system may serve a factor of low response to medication.
Karimova
M Kh
MKh
Mamysheva
O D
OD
Kubatiev
A A
AA
Petelin
L S
LS
D002395:Catecholamines / Q000652:urine*; D002908:Chronic Disease; D004351:Drug Resistance; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007980:Levodopa / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use; D010300:Parkinson Disease / Q000188:drug therapy / Q000652:urine*
D002395:Catecholamines; D010276:Parasympatholytics; D007980:Levodopa
Osobennosti ékskretsii katekholaminov u bol'nykh parkinsonizmom pri éffektivnom lechenii i terapevticheskoĭ rezistentnosti.