Ulex europaeus I and glycine max bind to the human olfactory bulb.
The distribution of binding sites for the fucose-selective lectin Ulex europaeus I and the terminal N-acetylgalactosamine-selective lectin glycine max in the human olfactory bulb were studied. These lectins bound to primary olfactory axons in the olfactory nerve layer and the glomerular layer. They also bound to fibers located in the deeper layers such as the external plexiform layer and the granular layer. Furthermore they projected to the olfactory stalk but not in the cerebrum. The deeper projections of the lectin binding fibers may affect the function of the olfactory bulb in humans.
Nagao
M
M
Department of Neurology, University of Kyoto, Japan.
Oka
N
N
Kamo
H
H
Akiguchi
I
I
Kimura
J
J
D000368:Aged; D000369:Aged, 80 and over; D001369:Axons / Q000378:metabolism / Q000648:ultrastructure; D015415:Biomarkers; D006651:Histocytochemistry; D006801:Humans; D037102:Lectins / Q000378:metabolism*; D008875:Middle Aged; D009412:Nerve Fibers / Q000378:metabolism / Q000648:ultrastructure; D009830:Olfactory Bulb / Q000378:metabolism / Q000648:ultrastructure*; D009832:Olfactory Nerve / Q000378:metabolism / Q000648:ultrastructure; D037121:Plant Lectins; D030262:Soybean Proteins; D013025:Glycine max / Q000502:physiology*; D010835:Phytohemagglutinins
D015415:Biomarkers; D037102:Lectins; D037121:Plant Lectins; D030262:Soybean Proteins; C036850:Ulex europaeus lectins; C028824:soybean lectin; D010835:Phytohemagglutinins