title: Plasma xanthine oxidase level and alcohol administration.
abstract: The acute administration of ethanol by gastric catheter significantly increases the plasma xanthine oxidase activity in both rats and hamsters without changing other enzyme activities--alanine aminotransferase and aspartate aminotransferase. The plasma xanthine oxidase level seems to be a sensitive marker of liver damage. Its higher activity due to the acute ethanol intoxication may have an impact on ethanol organ damage.
authors.affiliation: First Department of Medical Chemistry and Biochemistry, School of Medicine I, Charles University, Prague, Czech Republic.
authors.forename: T
authors.initials: T
authors.lastname: Zima
authors.forename: L
authors.initials: L
authors.lastname: Novák
authors.forename: S
authors.initials: S
authors.lastname: Stípek
mesh_terms: D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D006224:Cricetinae; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D000860:Hypoxia / Q000139:chemically induced; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D051381:Rats; D014969:Xanthine Oxidase / Q000097:blood* / Q000378:metabolism*
chemical_list: D000431:Ethanol; D014969:Xanthine Oxidase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase