Serum sialic acid levels in patients with sympathetic ophthalmitis.
Serum sialic acid levels were measured in 16 patients with sympathetic ophthalmitis, 36 with neglected traumatic uveitis following penetrating injury and 40 healthy subjects. There was no significant alteration of its level in patients with traumatic uveitis. However, its level was significantly elevated in patients with sympathetic ophthalmitis. It was high even in the early stage of the disease. It decreased significantly at the remission stage. It is proposed that measurement of sialic acid level in serum can be used as a diagnostic aid when the diagnosis of sympathetic ophthalmitis remains doubtful on clinical grounds. The extent of rise in its level may be considered a good parameter of the degree of severity of sympathetic ophthalmitis. It may also act as a useful tool to evaluate the drug efficacy in this disease.
Lamba
P A
PA
Guru Nanak Eye Centre, Department of Microbiology and Ophthalmology, Maulana Azad Medical College, New Delhi, India.
Pandey
P K
PK
Sarin
G S
GS
Mathur
M D
MD
D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D002648:Child; D015807:Eye Injuries, Penetrating / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019158:N-Acetylneuraminic Acid; D009879:Ophthalmia, Sympathetic / Q000097:blood*; D012794:Sialic Acids / Q000097:blood*; D014602:Uvea / Q000293:injuries; D014605:Uveitis / Q000097:blood / Q000209:etiology
D015415:Biomarkers; D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid