title: Clinical and prognostic investigations on M2/t(8;21) acute nonlymphocytic leukemia.
abstract: Clinical and prognostic investigations were conducted in 46 cases of M2/t(8;21) leukemia and 29 cases of M2/NN patients. Results showed that most patients with M2/t(8;21) were young males with higher incidence of extramedullary infiltrations. Complete remission rate was higher but with earlier relapse. The prognosis of patients with M2/t(8;21) with loss of one sexual chromosome was poor.
authors.affiliation: Research Institute of Hematology, Tongji Medical University, Wuhan.
authors.forename: F J
authors.initials: FJ
authors.lastname: Cheng
authors.forename: A D
authors.initials: AD
authors.lastname: Yang
authors.forename: H B
authors.initials: HB
authors.lastname: Fei
authors.forename: H
authors.initials: H
authors.lastname: Tian
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D002881:Chromosomes, Human, Pair 12; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D011379:Prognosis; D014178:Translocation, Genetic; D014998:Y Chromosome