Malignant solitary fibrous tumor of the pleura.
We describe a case of malignant solitary fibrous tumor of the pleura in a 15-year-old female who presented clinically with back pain. Grossly, the tumor had a pedicle attached to the pleura and histologically showed proliferating spindle-shaped cells with a high mitotic index. Immunohistochemical and ultrastructural features were consistent with a tumor of fibroblastic origin. Flow cytometric DNA analysis revealed an aneuploid population among the tumor cells.
Uzoaru
I
I
Department of Pathology, Children's Memorial Hospital, Northwestern University, Chicago, Illinois 60614.
Chou
P
P
Reyes-Mugica
M
M
D000293:Adolescent; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007124:Immunoenzyme Techniques; D018218:Neoplasms, Fibrous Tissue / Q000473:pathology* / Q000648:ultrastructure; D010997:Pleural Neoplasms / Q000473:pathology* / Q000648:ultrastructure