Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now?
Vaccination with tumor cells that have been engineered to express cytokine genes has been developed in animal models as a novel form of tumor therapy. Mario Colombo and Guido Forni assess the current situation and suggest a way forward.
Colombo
M P
MP
Divisione di Oncologia Sperimentale D, Istituto Nazionale Tumori, Milan, Italy.
Forni
G
G
D000818:Animals; D016207:Cytokines / Q000235:genetics / Q000276:immunology*; D015870:Gene Expression; D018014:Gene Transfer Techniques; D007167:Immunotherapy; D051379:Mice; D009374:Neoplasms, Experimental / Q000235:genetics / Q000276:immunology / Q000628:therapy*; D014162:Transfection; D014611:Vaccination
D016207:Cytokines