Angiotensin-converting enzyme inhibition and anaemia in renal patients.
A 35-year-old renal transplant patient with stable renal function developed an unexplained anaemia. Appropriate investigations proved non-diagnostic. Only when enalapril therapy was stopped did the anaemia reverse and haemoglobin levels returned to pre-treatment levels. An association between angiotensin-converting enzyme inhibitors and anaemia in patients with renal failure is becoming more evident. A literature review of this problem and its possible pathogenesis in patients with renal failure is given.
Korzets
A
A
Department of Nephrology, Golda Medical Center, Petach-Tikva, Israel.
Zevin
D
D
Chagnac
A
A
Gafter
U
U
Weinstein
T
T
Ori
Y
Y
Levi
J
J
D000328:Adult; D000740:Anemia / Q000097:blood / Q000139:chemically induced*; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D004656:Enalapril / Q000008:administration & dosage / Q000009:adverse effects*; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000188:drug therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications / Q000628:therapy; D011183:Postoperative Complications / Q000097:blood / Q000628:therapy
D007166:Immunosuppressive Agents; D004656:Enalapril