Repair resistance of O6-methylguanine in DNA of hamster fibroblasts expressing a bacterial alkyltransferase gene is dependent on chromatin structure.
Gordon
A T
AT
Department of Biochemistry, Nottingham University Medical School, UK.
Manning
F C
FC
Cooper
D P
DP
Margison
G P
GP
O'Connor
P J
PJ
Billett
M A
MA
D000818:Animals; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D002843:Chromatin / Q000378:metabolism* / Q000648:ultrastructure; D002999:Clone Cells; D006224:Cricetinae; D004247:DNA / Q000187:drug effects / Q000302:isolation & purification / Q000378:metabolism*; D004249:DNA Damage; D004260:DNA Repair; D004926:Escherichia coli / Q000201:enzymology; D029968:Escherichia coli Proteins; D005798:Genes, Bacterial; D006147:Guanine / Q000031:analogs & derivatives* / Q000378:metabolism; D008770:Methylnitrosourea / Q000633:toxicity; D008780:Methyltransferases / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D019853:O(6)-Methylguanine-DNA Methyltransferase; D014157:Transcription Factors; D014162:Transfection
D001426:Bacterial Proteins; D002843:Chromatin; D029968:Escherichia coli Proteins; D014157:Transcription Factors; D006147:Guanine; D008770:Methylnitrosourea; D004247:DNA; C008449:O-(6)-methylguanine; D008780:Methyltransferases; C045675:Ada protein, E coli; D019853:O(6)-Methylguanine-DNA Methyltransferase