title: [Effect of occupational lead exposure on the immunoglobulin concentration and cellular immune function in man].
abstract: The evaluation of immunological conditions of 14 workers occupationally exposed to lead and comparison of these results with those of a non-exposed control group with similar age and sex were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 ug/dl while in the control group it was 10.9 ug/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant diminishment in the formation of rosette in relation to the control group.
authors.affiliation: Sección de Alergia e Inmunología Clínica, Instituto de Medicina del Trabajo, Ciudad de la Habana, Cuba.
authors.forename: A
authors.initials: A
authors.lastname: Castillo Méndez
authors.forename: T
authors.initials: T
authors.lastname: Rodríguez Díaz
authors.forename: A
authors.initials: A
authors.lastname: León Lobeck
authors.forename: A J
authors.initials: AJ
authors.lastname: Gravalosa Cruz
mesh_terms: D000328:Adult; D000818:Animals; D002617:Chemical Industry; D006801:Humans; D017099:IgG Deficiency / Q000139:chemically induced; D007111:Immunity, Cellular / Q000187:drug effects*; D007136:Immunoglobulins / Q000097:blood*; D007153:Immunologic Deficiency Syndromes / Q000139:chemically induced*; D007854:Lead / Q000009:adverse effects* / Q000097:blood / Q000494:pharmacology / Q000633:toxicity; D007958:Leukocyte Count / Q000187:drug effects; D016273:Occupational Exposure; D051381:Rats; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000187:drug effects
chemical_list: D007136:Immunoglobulins; D007854:Lead
vernacular_title: Influencia de la exposición ocupacional al plomo sobre la concentración de inmunoglobulinas y la función celular inmune en el hombre.