[Effectiveness of lecedil (famotidine) in the therapy of patients with peptic ulcer].
A total of 30 patients (29 with peptic ulcer and 2 with erosive gastroduodenitis) received lecedil, a new famotidine blocker of histamine H2-receptors. The effect of the drug was not related to the dose regimen (20 mg twice or 40 once a day). In good tolerance side effects were not reported. Healing of duodenal ulcer occurred within 4 and 5 treatment weeks in 17 (85.0%) and 19 (95.0%) out of 20 patients, respectively, within 6 and 8 treatment weeks ulcer healed in 5 and 6 out of 8 gastric ulcer patients, respectively.
Grebenev
A L
AL
Sheptulin
A A
AA
Smakov
G M
GM
Kornienko
A A
AA
Trukhmanov
A S
AS
D000328:Adult; D015738:Famotidine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000188:drug therapy*; D016896:Treatment Outcome
D015738:Famotidine
Effektivnost' primeneniia letsedila (famotidina) v lechenii bol'nykh iazvennoĭ bolezn'iu.