Hospital-acquired infections in pediatric burn patients.
To determine the epidemiologic characteristics of hospital-acquired infections (HAI) in pediatric burn patients, we retrospectively reviewed hospital charts of pediatric burn patients from two similar burn units. All patients less than 18 years of age admitted to the burn unit from January 1, 1980 to July 10, 1988, were enrolled. Charts were analyzed for age, sex, burn injury (type, depth, burn surface area), and hospital course (burn wound therapy, use of indwelling catheters or tubes, infectious complications, antibiotic use, cause of death if patient died). Statistical analysis was done using a logistic regression model. Of the 224 children admitted, 32 (14%) had 58 infections during their stay in the burn unit. There was no significant difference in age, sex, race, burn type or use of wound excision between patients with or without infection. Patients who acquired an infection were more likely to have sustained a > or = 20% full-thickness burn (14/32 vs 3/192 without infection), a smoke inhalation injury (10/32 vs 8/192), or have an indwelling device (29/32 vs 77/192). Thirteen (22%) of the 58 infections were burn wound infections due to Staphylococcus aureus or Pseudomonas aeruginosa, 12 (21%) were urinary tract infections due to Enterobacteriaceae, 11 (19%) were pneumonias caused by S aureus, Streptococcus pneumoniae or Pseudomonas sp, and 10 (17%) were bacteremias caused by S aureus or coagulase-negative staphylococci. The infection rate in pediatric patients hospitalized for burn injury in our study was significantly lower than the infection rate described for adult burn patients. As in adult patients, burn wound infections, pulmonary infections, and catheter-associated bacteremias are the most common infections in burned children. However, urinary tract infections are more frequent in the pediatric population. Risk factors (> or = 20% full-thickness burns, indwelling devices) and causative organisms are similar in both age groups.
Schlager
T
T
Department of Pediatrics, University of Virginia, Charlottesville 22908.
Sadler
J
J
Weber
D
D
Donowitz
L
L
Lohr
J
J
D000293:Adolescent; D002053:Burn Units / Q000706:statistics & numerical data*; D002056:Burns / Q000150:complications* / Q000382:microbiology; D002059:Burns, Inhalation / Q000150:complications; D002408:Catheters, Indwelling / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D016015:Logistic Models; D008297:Male; D009657:North Carolina / Q000453:epidemiology; D011552:Pseudomonas Infections / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology*; D013290:Streptococcal Infections / Q000453:epidemiology; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000382:microbiology; D014768:Virginia / Q000453:epidemiology