title: Small cell carcinoma of the esophagus. Clinicopathological and immunohistochemical findings in four cases.
abstract: Small cell carcinoma of the esophagus is an uncommon neoplasm. The authors report the clinicopathologic and immunohistochemical findings in four cases. Dysphagia was the most frequent symptom at presentation. Only one patient was treated by surgery; the other did not receive any treatment. Histologically, three were oat-cell type tumors with areas of intermediate cell type. Combined cell type was not present. Immunohistochemistry demonstrated positivity for neuron-specific enolase and for chromogranin in all four cases. One case was a double primary carcinoma, a squamous cell carcinoma and a small cell carcinoma.
authors.affiliation: Department of Pathology, Federal University of Santa Maria, RS, Brazil.
authors.forename: C R
authors.initials: CR
authors.lastname: Melo
authors.forename: I S
authors.initials: IS
authors.lastname: Melo
authors.forename: C T
authors.initials: CT
authors.lastname: Cerski
mesh_terms: D000328:Adult; D000368:Aged; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged