[The effect of endogenous opioid peptides and their synthetic analogs on the activity of natural killer cells].
Met- and leu-enkephalins and their synthetic analogs DAGO, DADLE, and dalargin were tested for their effects on the activity of natural killer cells. The endogenous opioid peptides and dalargin were shown to be able to enhance the cytolytic activity of natural killer cells.
Uteshev
B S
BS
Korostelev
S A
SA
Isakova
K L
KL
Shchegolev
A I
AI
D000818:Animals; D002478:Cells, Cultured / Q000187:drug effects / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D004305:Dose-Response Relationship, Drug; D004723:Endorphins / Q000494:pharmacology*; D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D004745:Enkephalins / Q000494:pharmacology*; D007111:Immunity, Cellular / Q000187:drug effects; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000276:immunology; D007942:Leukemia, Experimental; D051379:Mice; D008809:Mice, Inbred C3H; D013268:Stimulation, Chemical; D014407:Tumor Cells, Cultured
D004723:Endorphins; D004745:Enkephalins; D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Vliianie éndogennykh opioidnykh peptidov i ikh sinteticheskikh analogov na aktivnost' estestvennykh killernykh kletok.