Thyroid function and attention-deficit hyperactivity disorder.
OBJECTIVE
To examine thyroid indices in a community referred sample of boys with attention-deficit hyperactivity disorder (ADHD) for evidence of generalized resistance to thyroid hormone (GRTH).


METHODS
TSH, T3, and T4 values were gathered prospectively in 53 physician, school, and/or parent referred ADHD subjects, and in 41 age and gender-matched normal controls.


RESULTS
None were in the range suggestive of global or pituitary thyroid hormone resistance.


CONCLUSIONS
GRTH is rare, and thyroid function should not be measured routinely in nonfamilial ADHD.
Elia
J
J
Department of Psychiatry, Medical College of Pennsylvania, Philadelphia.
Gulotta
C
C
Rose
S R
SR
Marin
G
G
Rapoport
J L
JL
D001289:Attention Deficit Disorder with Hyperactivity / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D002648:Child; D003913:Dextroamphetamine / Q000627:therapeutic use; D004311:Double-Blind Method; D005067:Euthyroid Sick Syndromes / Q000097:blood / Q000175:diagnosis* / Q000235:genetics / Q000523:psychology; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use; D019965:Neurocognitive Disorders / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D013960:Thyroid Function Tests; D013963:Thyroid Hormones / Q000097:blood
D013963:Thyroid Hormones; D008774:Methylphenidate; D003913:Dextroamphetamine