[Detection of DNA adducts and their persistence in leucocytes of benzene-exposed mice].
DNA adducts in peripheral leucocytes of mice injected intraperitoneally with benzene were assayed by 32P-postlabelling technique. Results showed two kinds, at least, of DNA adducts could be formed in the mice, and they could still be detected 3 weeks after exposure. It laid a preliminary basis for further studies on the DNA adducts as biological markers for monitoring occupational exposure to benzene.
Wang
C G
CG
Qingdao Medical College.
D000818:Animals; D001554:Benzene / Q000633:toxicity*; D004247:DNA / Q000378:metabolism*; D005260:Female; D007274:Injections, Intraperitoneal; D007962:Leukocytes / Q000378:metabolism*; D051379:Mice; D010761:Phosphorus Radioisotopes
D010761:Phosphorus Radioisotopes; D004247:DNA; D001554:Benzene