Regression of cardiac insufficiency after ambulatory intravenous deferoxamine in thalassemia major.
A case of severe cardiac failure due to iron overload in a patient with beta-thalassemia major is reported. The patient was successfully treated with high-dose ambulatory intravenous deferoxamine (desferrioxamine). This type of chelation appears to be a valuable alternative to subcutaneous deferoxamine administration in the presence of severe iron overload.
Wacker
P
P
Department of Pediatrics, Hôpital Cantonal Universitaire.
Halperin
D S
DS
Balmer-Ruedin
D
D
Oberhansli
I
I
Wyss
M
M
D000328:Adult; D000553:Ambulatory Care; D003676:Deferoxamine / Q000008:administration & dosage*; D004452:Echocardiography; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D017086:beta-Thalassemia / Q000150:complications* / Q000628:therapy*
D003676:Deferoxamine