title: Early-onset respiratory failure caused by severe congenital neuromuscular disease.
abstract: Two unrelated infants with low Apgar scores, pneumothoraces, and severe pulmonary hypertension were treated with extracorporeal membrane oxygenation while receiving chemical sedation and neuromuscular paralysis. After decannulation from extracorporeal membrane oxygenation, hypotonia and hypoventilation persisted. Neurologic evaluation confirmed that both infants had a congenital myopathy.
authors.affiliation: Department of Pediatrics, Univeristy of Florida College of Medicine, Gainesville.
authors.forename: D L
authors.initials: DL
authors.lastname: Sandler
authors.forename: D J
authors.initials: DJ
authors.lastname: Burchfield
authors.forename: J A
authors.initials: JA
authors.lastname: McCarthy
authors.forename: A M
authors.initials: AM
authors.lastname: Rojiani
authors.forename: W H
authors.initials: WH
authors.lastname: Drummond
mesh_terms: D015199:Extracorporeal Membrane Oxygenation; D017809:Fatal Outcome; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009468:Neuromuscular Diseases / Q000150:complications / Q000151:congenital*; D010547:Persistent Fetal Circulation Syndrome / Q000150:complications* / Q000628:therapy; D012131:Respiratory Insufficiency / Q000209:etiology*