title: [Study on decision support system for the interpretation of laboratory data by an artificial neural network--with a special reference to estimation for histological diagnosis of liver diseases with laboratory data on liver function].
abstract: An artificial neural network (ANN) was trained on laboratory data of liver function tests to estimate for histological diagnosis in patients with liver diseases such as chronic hepatitis, liver cirrhosis and fatty liver. ANN diagnosed accurately 95.3% of the cases for training and 50% of the test cases. Elimination of ZTT, GOT or A/G ratio from the data set for input reduced the ability of accurate diagnosis, whereas elimination of TBA raised this ability to 66.7%. On the other hand, accuracy of physician in diagnosing the test cases ranged from 20.8 to 62.5%. From our results it is expected that ANN may support a physician's decision on the interpretation of laboratory data.
authors.affiliation: Department of Clinico-Laboratory Diagnostics, Nara Medical University, Kashihara.
authors.forename: Y
authors.initials: Y
authors.lastname: Okamoto
authors.forename: H
authors.initials: H
authors.lastname: Nakano
authors.forename: M
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: H
authors.initials: H
authors.lastname: Matsuoka
authors.forename: T
authors.initials: T
authors.lastname: Sakamoto
authors.forename: T
authors.initials: T
authors.lastname: Tsujii
mesh_terms: D000465:Algorithms; D003936:Diagnosis, Computer-Assisted; D005103:Expert Systems; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D008111:Liver Function Tests; D008297:Male; D016571:Neural Networks, Computer