Screening-detected and symptomatic ductal carcinoma in situ: mammographic features with pathologic correlation.
OBJECTIVE
To compare the mammographic and pathologic features of screening-detected and symptomatic ductal carcinoma in situ (DCIS).


METHODS
The mammographic and pathologic features of 54 screening-detected and 77 symptomatic cases of DCIS were compared. Patients were aged 30-76 years (mean, 58 years).


RESULTS
Diffuse involvement was seen in 10 patients (13%) with symptoms but in none of the screening-detected group (P < .05). The disease was radiologically more extensive in the symptomatic group. Calcifications in the symptomatic group (n = 48) were less likely to have a ductal distribution than those in the screening-detected group (n = 48) (30 [63%] vs 40 [83%], respectively; P < .05). At histologic examination in some cases, the symptomatic group (n = 76) included eight (11%) patients with cribriform-micropapillary, large-cell tumors (P < .05) and less comedocarcinoma (20 [26%] vs 23 [45%], respectively; P < .05) compared with the screening-detected group (n = 51).


CONCLUSIONS
The results show differences in the radiologic and pathologic features of screening-detected and symptomatic DCIS.
Evans
A J
AJ
Department of Radiology, Nottingham City Hospital, England.
Pinder
S
S
Ellis
I O
IO
Sibbering
M
M
Elston
C W
CW
Poller
D N
DN
Wilson
R
R
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged