Electron-beam therapy in scleredema adultorum with associated monoclonal hypergammaglobulinaemia.
We report a case of scleredema adultorum (Buschke's disease) associated with an IgA kappa monoclonal hypergammaglobulinaemia. A significant improvement in the skin was obtained with electron-beam therapy. Scleredema would appear to be linked to monoclonal hypergammaglobulinaemia, but the relationship between the skin disorder and the immunoglobulin abnormality remains to be elucidated.
Angeli-Besson
C
C
Department of Dermatology, CHU la Timone, Marseille, France.
Koeppel
M C
MC
Jacquet
P
P
Andrac
L
L
Sayag
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D004583:Electrons; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains; D008297:Male; D008875:Middle Aged; D011882:Radiotherapy, High-Energy; D012592:Scleredema Adultorum / Q000150:complications / Q000473:pathology / Q000532:radiotherapy*
D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains