[Alpha-heavy chain disease--Mediterranean lymphoma].
For 6 months diarrhea and weight loss of 30 kg occurred in a 28 year old man from the Emirates. The endoscopic examination suggested a small intestinal lymphoma affecting the entire small intestine, which was confirmed by biopsies, immunohistochemistry, immunologic proof of monoclonal IgA-gammopathy in serum and urine. The patient acquired a malignant MALT-lymphoma of B-cell-type, a alpha-Heavy Chain Disease, synonym mediterranean lymphoma or immunoproliferative small intestinal disease (IPSID), stage A with transition in stage B. The patient was treated with ciprofloxacine in association with metronidazole with no influence of the course of the disease.
Kaufmann
H P
HP
I. Med. Abteilung, Städt. Krankenhaus München-Neuperlach, Akademisches Lehrkrankenhaus.
Schmitt
W
W
Seib
H J
HJ
D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D007161:Immunoproliferative Small Intestinal Disease / Q000175:diagnosis* / Q000473:pathology; D007413:Intestinal Mucosa / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D009367:Neoplasm Staging; D010950:Plasma Cells / Q000473:pathology
Alpha-Schwerkettenkrankheit--Mediterranes Lymphom.