Homotransplantation of testis. A report of 11 cases.
Testis homotransplantation has been carried out in 11 patients since 1986. Of them, 8 suffered from congenital testicular dysplasia and the other 3 from orchiatrophy as a result of orchitis. Preoperatively, manifestations were a small penis, small testes, sexual dysfunction, indistinct secondary sex characteristics and low serum testosterone (1.7-7.35 mmol/L). Three cases had cadaver transplants and 8 had living relatives' transplants. The patients were followed up for 7 months to 4 years. The secondary sex characteristics and sexual function were improved remarkably after transplantation. Serum testosterone increased up to 12.8-18.2 mmol/L. All of 5 married patients resumed sexual intercourse satisfactorily. Three others got married after transplantation and have enjoyed normal sexual functions. Spermatozoa have been found in the semen in 3 of the cases.
Zhao
G X
GX
Department of Urology, 1st Affiliated Hospital, Henan Medical University, Zhengzhou.
Bai
Y X
YX
Yang
T S
TS
He
C Q
CQ
Chen
Y T
YT
Qiao
B P
BP
Jiang
H Y
HY
D000328:Adult; D006059:Gonadal Dysgenesis / Q000601:surgery*; D006801:Humans; D008297:Male; D013733:Testicular Diseases / Q000601:surgery*; D013737:Testis / Q000002:abnormalities / Q000637:transplantation*; D013739:Testosterone / Q000097:blood
D013739:Testosterone