High-affinity and potent, water-soluble 5-amino-1,4-benzodiazepine CCKB/gastrin receptor antagonists containing a cationic solubilizing group.
Showell
G A
GA
Merck, Sharp and Dohme Research Laboratories, Neuroscience Research Center, Harlow Essex, United Kingdom.
Bourrain
S
S
Neduvelil
J G
JG
Fletcher
S R
SR
Baker
R
R
Watt
A P
AP
Fletcher
A E
AE
Freedman
S B
SB
Kemp
J A
JA
Marshall
G R
GR
D000818:Animals; D001569:Benzodiazepines / Q000138:chemical synthesis / Q000494:pharmacology*; D006801:Humans; D011949:Receptors, Cholecystokinin / Q000037:antagonists & inhibitors*; D012995:Solubility; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D011949:Receptors, Cholecystokinin; D001569:Benzodiazepines