title: The comparative efficacy of antecedent exercise and methylphenidate: a single-case randomized trial.
abstract: This study evaluated the comparative efficacy of antecedent exercise, methylphenidate (Ritalin), and placebo in the reduction of hyperactive behaviour in a pre-school boy. A single-case alternating treatments experimental design was employed for a total of 82 days. The dependent variable was the Conners' Abbreviated Symptom Questionnaire. Antecedent exercise failed to reduce hyperactive behaviour. Methylphenidate produced significantly less hyperactive behaviour than both placebo and antecedent exercise (P = 0.0238). Neither methylphenidate nor antecedent exercise produced notable side-effects as measured by the Monitoring of Side-Effects Scale. These data add to a sparse literature on the effects of antecedent exercise and methylphenidate amongst pre-school children.
authors.affiliation: Milestone School for Child Development, Brooklyn, NY.
authors.forename: J M
authors.initials: JM
authors.lastname: Silverstein
authors.forename: D B
authors.initials: DB
authors.lastname: Allison
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004519:Education, Special; D006801:Humans; D007590:Jogging; D008297:Male; D008774:Methylphenidate / Q000008:administration & dosage*
chemical_list: D008774:Methylphenidate