[A biochemical study of creatine phosphokinase in the myocardium and its morphological changes in patients with acute vascular surgical pathology].
The structure and metabolism of various myocardial portions, including the activity of creatine phosphokinase (CPK), were studied by using the autopsies of patients who had died in a surgical clinic. The biochemical studies demonstrated a decrease in CPK activity, which was pronounced in patients with atherosclerotic aneurysm and abdominal aortic rupture. The morphological studies revealed individual cardiomyocytic lesions, segmental lesions of papillary muscle. There was reduced activity of redox enzymes in the fragmentation areas of muscle fibers. Various surgical abnormality of vessels was accompanied by progressive myocardial hypoxia and drastically decreased activity of CPK and the tested hydroxyreductases.
Trusov
O A
OA
Avilov
V V
VV
Mozhina
A A
AA
Tsareva
L A
LA
D000208:Acute Disease; D000328:Adult; D000368:Aged; D001344:Autopsy; D003402:Creatine Kinase / Q000378:metabolism*; D006333:Heart Failure / Q000150:complications / Q000201:enzymology* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000201:enzymology* / Q000473:pathology*; D013997:Time Factors
D003402:Creatine Kinase
Biokhimicheskoe izuchenie kreatinfosfokinazy miokarda i ego morfologicheskie izmeneniia u bol'nykh s ostroĭ sosudistoĭ khirurgicheskoĭ patologieĭ.