Antidepressant effect of lithium in patients with systemic lupus erythematosus and cerebral infarction, treated with corticosteroid.
Two depressive patients with systemic lupus erythematosus (SLE) and cerebral infarction, while being treated with corticosteroid, are described. In both cases, lithium was remarkably effective and no severe side-effects occurred. These findings suggest that lithium can be a useful antidepressant agent in the treatment of depressive SLE patients.
Terao
T
T
Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Mizuki
T
T
Ohji
T
T
Abe
K
K
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D002544:Cerebral Infarction / Q000188:drug therapy* / Q000523:psychology; D003866:Depressive Disorder / Q000139:chemically induced / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects / Q000627:therapeutic use*; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy* / Q000523:psychology; D008803:Mianserin / Q000009:adverse effects / Q000627:therapeutic use; D019965:Neurocognitive Disorders / Q000188:drug therapy* / Q000523:psychology; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D019966:Substance-Related Disorders / Q000188:drug therapy* / Q000523:psychology
D000305:Adrenal Cortex Hormones; D008803:Mianserin; D008094:Lithium; D011239:Prednisolone