Current principles of hygienic standards setting (Part II).
The paper presents general principles of setting the hygienic standards for substances of threshold effect and nonthreshold agents. The authors introduced the mathematical models used for quantitative risk assessment and models for assessment of the dose-response relationship according to the physiological principles.
Czerczak
S
S
Department of Scientific Information, Nofer Institute of Occupational Medicine, Lodz, Poland.
Indulski
J A
JA
Kowalski
Z
Z
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure; D015386:Hazardous Substances / Q000009:adverse effects* / Q000493:pharmacokinetics; D006291:Health Policy; D006801:Humans; D016014:Linear Models; D008452:Maximum Allowable Concentration; D015233:Models, Statistical; D008962:Models, Theoretical; D009369:Neoplasms / Q000139:chemically induced / Q000517:prevention & control; D009787:Occupational Medicine / Q000592:standards*; D012306:Risk
D015386:Hazardous Substances