Interaction of thyroxine and testosterone in stimulating muscle protein breakdown in female broiler chickens.
1. The effects of thyroxine (T4), testosterone propionate (TP) and a combination of hormone treatments on growth and the rates of muscle protein breakdown estimated by Ntau-methylhistidine excretion were studied. 2. Broiler chickens aged from 15 d to 27 d were used; T4 and TP were mixed in the basal diet at concentrations of 1.2 and 20 mg/kg respectively. 3. Although growth was not altered significantly by any treatment, the rate of muscle protein breakdown was significantly increased about 2-fold by the combined treatment, but not by treatment with T4 or TP alone.
Hayashi
K
K
Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University, Japan.
Michioka
M
M
Tomita
Y
Y
D000818:Animals; D002645:Chickens / Q000254:growth & development / Q000378:metabolism*; D005260:Female; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*; D013739:Testosterone / Q000494:pharmacology*; D013974:Thyroxine / Q000494:pharmacology*
D013739:Testosterone; D013974:Thyroxine