title: [The optimization of the captopril treatment of patients with stage-II hypertension at polyclinics].
abstract: To optimize captopril therapy of patients suffering from stage II essential hypertension under ambulant conditions, use was made of an acute medicamentous test with that drug. The long-term systematic therapy (for a year) was provided to 50 patients with positive results of the test. The long-term systematic captopril therapy in individually selected doses led to a decrease and stabilization of blood pressure, minimized subjective disease manifestations and improved hemodynamic characteristics. The application of the drug in moderate doses prevented the development of side effects that might require drug discontinuance.
authors.forename: M P
authors.initials: MP
authors.lastname: Mikhaĭlusova
authors.forename: B Ia
authors.initials: BIa
authors.lastname: Bart
authors.forename: N A
authors.initials: NA
authors.lastname: Stadchenko
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D001794:Blood Pressure / Q000187:drug effects; D002216:Captopril / Q000008:administration & dosage*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D013997:Time Factors
chemical_list: D002216:Captopril
vernacular_title: Optimizatsiia lecheniia bol'nykh gipertonicheskoĭ bolezn'iu II stadii v poliklinicheskikh usloviiakh.