[Effect of pyridoxal phosphate on the activity of aminotransferases in different structure-functional regions of the rabbit brain in radiation sickness].
Pyridoxal enzymes of transamination (aspartate aminotransferase, KF 2.6.1.1. and alanine aminotransferase, KF 2.6.1.2) have been studied for their activity in different departments of the rabbit brain under the effect of ionizing radiation and introduction of pyridoxal phosphate. It has been established that the effect of ionizing radiations does not evoke the change in aspartate aminotransferase and alanine aminotransferase activity in different structure-functional departments of the rabbit brain, the decrease of aminotransferases activity in the acute period of the radiation sickness being natural. Introduction of pyridoxal phosphate irradiated animals promotes relative normalization of activity of the enzymes under study.
Nagiev
E R
ER
Tsybul'skiĭ
V V
VV
D000410:Alanine Transaminase / Q000187:drug effects*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000187:drug effects*; D011732:Pyridoxal Phosphate / Q000494:pharmacology*; D011817:Rabbits; D011833:Radiation Injuries, Experimental / Q000201:enzymology*
D011732:Pyridoxal Phosphate; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Vliianie piridoksal'fosfata na aktivnost' aminotransferaz v razlichnykh strukturno-funktsional'nykh otdelakh golovnogo mozga krolikov pri luchevoĭ bolezni.