title: Effect of halofuginone on broiler skin strength when used in a shuttle anticoccidial program.
abstract: Continuous feeding of the anticoccidial halofuginone to broilers is associated with reduced skin tensile strength and increased skin tearing during processing. The possible mitigating effect of shuttle administration of halofuginone and salinomycin to female broilers was evaluated. Halofuginone or salinomycin were included in the starter and grower diets in all four possible combinations, with anticoccidial omitted from the finisher diets. Starter, grower, and finisher diets were fed to broilers through 3, 6, and 7 wk of age, respectively. Skin strength of pullets fed a diet based on milo and corn (NW) vs a diet based on corn was also compared in a factorial arrangement. Two further treatments were also included: 1) halofuginone-only NW diet supplemented with 2,500 ppm ascorbic acid from 0 to 7 wk; and 2) NW diet reared on wire floor without anticoccidial treatment. Skin tensile strength was determined at 3, 6, and 7 wk of age. Dietary composition had no effect upon skin strength or BW of broilers. Addition of ascorbic acid to the diet containing halofuginone anticoccidial did not improve skin strength. Continuous feeding of halofuginone reduced skin strength whereas withholding anticoccidial and continuous feeding of salinomycin resulted in high skin strength. When halofuginone was used in shuttle feeding programs with salinomycin, there were no differences in skin strength at 7 wk of age compared to birds that were continuously treated with salinomycin. These results suggest halofuginone may be used in a shuttle program either during the starter or grower phase without adverse affect on skin tensile strength at slaughter.
authors.affiliation: Washington State University, Puyallup Research and Extension Center, Washington 98371-4998.
authors.forename: N G
authors.initials: NG
authors.lastname: Zimmermann
authors.forename: K D
authors.initials: KD
authors.lastname: Christensen
authors.forename: C L
authors.initials: CL
authors.lastname: Wyatt
authors.forename: P
authors.initials: P
authors.lastname: Twining
mesh_terms: D000821:Animal Feed; D000818:Animals; D002645:Chickens / Q000502:physiology*; D003049:Coccidiostats / Q000008:administration & dosage*; D004032:Diet / Q000662:veterinary; D004334:Drug Administration Schedule / Q000662:veterinary; D005260:Female; D010880:Piperidines; D011714:Pyrans / Q000008:administration & dosage; D011799:Quinazolines / Q000008:administration & dosage*; D052999:Quinazolinones; D012867:Skin / Q000187:drug effects; D012879:Skin Physiological Phenomena; D013718:Tensile Strength / Q000187:drug effects; D000095662:Polyether Polyketides
chemical_list: D003049:Coccidiostats; D010880:Piperidines; D011714:Pyrans; D011799:Quinazolines; D052999:Quinazolinones; C010327:salinomycin; D000095662:Polyether Polyketides; C010176:halofuginone