title: Alcohol consumption by C57BL/6, BALB/c, and DBA/2 mice in a limited access paradigm.
abstract: Alcohol consumption by three inbred mice strains in a limited access condition was examined. Access to "Richter" tubes containing alcohol solution was restricted to 60 min per day in a drinking cage. Alcohol solution was given in escalating concentrations starting at 3% and ending at 12% w/v over several days. During the 12% phase, C57 mice consumed an average of 1.68 g/kg, while BALB and DBA mice consumed an average of 0.66 and 0.25 g/kg, respectively. The C57BL/6 mice achieved an average blood alcohol level (BAL) of 60 mg%, whereas the other two strains displayed negligible levels. The relationship between alcohol intake in a continuous and limited access as well as the utility of the limited access paradigm are discussed.
authors.affiliation: Addiction Research Foundation of Ontario, Toronto, Canada.
authors.forename: A D
authors.initials: AD
authors.lastname: Lê
authors.forename: J
authors.initials: J
authors.lastname: Ko
authors.forename: S
authors.initials: S
authors.lastname: Chow
authors.forename: B
authors.initials: B
authors.lastname: Quan
mesh_terms: D000428:Alcohol Drinking / Q000235:genetics / Q000523:psychology*; D000818:Animals; D004326:Drinking / Q000502:physiology; D000431:Ethanol / Q000097:blood; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D013045:Species Specificity
chemical_list: D000431:Ethanol