Effective mucosal immunity. Current concepts for vaccine delivery and immune response analysis.
It is now established that the mucosal immune system is a separate entity and is regulated in a different fashion than that in peripheral lymphoid tissues (the systemic immune system). In this brief review, five selected areas within the field of mucosal immunity are discussed in the context of the goals for vaccines for the Children's Vaccine Initiative.
McGhee
J R
JR
University of Alabama at Birmingham.
Kiyono
H
H
D001402:B-Lymphocytes / Q000276:immunology*; D001940:Breast / Q000276:immunology*; D015195:Drug Design; D004341:Drug Evaluation; D005544:Forecasting; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D007156:Immunologic Memory; D007413:Intestinal Mucosa / Q000276:immunology*; D007765:Lacrimal Apparatus / Q000276:immunology*; D009297:Nasal Mucosa / Q000276:immunology*; D012469:Salivary Glands / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D014612:Vaccines / Q000276:immunology*
D007070:Immunoglobulin A; D014612:Vaccines