Fc epsilon RI on human Langerhans cells: a receptor in search of new functions.
The recent demonstration that the high-affinity receptor for IgE, Fc epsilon RI, is expressed on human Langerhans cells casts a new perspective on the function of this receptor. This observation also provides a new direction for further investigation into the pathophysiological relevance of Langerhans cells and other antigen-presenting cells in the development of atopic diseases.
Bieber
T
T
Dept of Dermatology, Ludwig-Maximilians University, Munich, Germany.
D000938:Antigen-Presenting Cells / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000502:physiology; D007801:Langerhans Cells / Q000502:physiology*; D017455:Receptors, IgE / Q000502:physiology*
D017455:Receptors, IgE; D007073:Immunoglobulin E