title: Case report of an intracarotid amobarbital procedure performed for a deaf patient.
abstract: The intracarotid amobarbital procedure (IAP) was conducted with a profoundly deaf young man prior to right anteromedial temporal lobectomy for pharmacologically refractory partial complex seizures. The IAP required considerable modification in order to take into account the use of varying sign language methods and related issues. Visual memory, American Sign Language, signed English, and finger-spelling functioning were all assessed. The patient manifested left hemisphere dominance for all these abilities, performing well under right hemisphere anesthesia. In contrast, no ability to function on these tasks was detectable when the left hemisphere was anesthetized. This demonstrates that an intact left temporal lobe and related structures are sufficient to support sign language functioning. The development of a deaf adaptation of the IAP is of methodological significance, as the IAP is thereby rendered accessible for deaf patients.
authors.affiliation: Gallaudet Research Institute, Washington, DC 20002.
authors.forename: A B
authors.initials: AB
authors.lastname: Wolff
authors.forename: K J
authors.initials: KJ
authors.lastname: Sass
authors.forename: J
authors.initials: J
authors.lastname: Keidan
mesh_terms: D000328:Adult; D000654:Amobarbital; D002343:Carotid Artery, Internal; D003145:Communication Methods, Total; D003638:Deafness / Q000503:physiopathology*; D004292:Dominance, Cerebral / Q000502:physiology*; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000503:physiopathology / Q000601:surgery*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D011939:Mental Recall / Q000502:physiology; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual / Q000502:physiology; D011183:Postoperative Complications / Q000503:physiopathology; D011612:Psychosurgery; D012813:Sign Language; D013702:Temporal Lobe / Q000503:physiopathology / Q000601:surgery
chemical_list: D000654:Amobarbital