[Antioxidant therapy in the arrhythmic form of alcoholic heart damage].
The impact of antioxidative therapy with dibunol on the clinical course of an arrhythmic type of alcoholic damage was studied. A total of 20 patients with Stage II chronic alcoholism (mean age 38.1 +/- 1.9 years) and ventricular premature contraction were examined. The diagnosis of cardiac alcoholic damage was established after comprehensive studies. The effects of dibunol on the pattern of ventricular arrhythmias were tested by 24--hour Holter monitoring: control, on days 10 and 20 of therapy. The daily dosage of dibunol was 20 mg per kg body weight. The results of studies suggest that dibunol exerts a beneficial effect on the clinical course of the disease and the nature of ventricular arrhythmias by reducing the number of ventricular extrasystoles by 51.4%.
Gorgaslidze
A G
AG
Sumaĭaia
M
M
Esshchanova
F S
FS
Golitsyna
L S
LS
Smetnev
A S
AS
D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage; D002310:Cardiomyopathy, Alcoholic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D004341:Drug Evaluation; D015716:Electrocardiography, Ambulatory / Q000187:drug effects; D006801:Humans
D000975:Antioxidants; D002084:Butylated Hydroxytoluene
Antioksidantnaia terapiia pri aritmicheskoĭ forme alkogol'nogo porazheniia serdtsa.