title: Transfer factor and its signification for practice.
abstract: In the study literary data are given together with our own experience with the immunomodulation effects of Transfer Factor (TF) Sevac. The application of 3-5 ampulles of TF leads not only to E rosettes but even to a separate subpopulations of T lymphocytes increase. The results obtained in 51 patients with GIT and renal cells carcinoma were statistically evaluated. About 80% of the patients experienced an improvement of subjective conditions during the treatment. Objectively supported adjustment of laboratory indices was found in 83-88% of the parameters evaluated. Also the absolute numbers of CD4+ cells in 10(9)/1 increased (at p < 0.001) together with CD3+ and CD8+ (p < 0.01). A significant correlation between separate subpopulations of T lymphocytes and B lymphocytes was proved in the original mode. From our results it is obvious that the TF Sevac application and further observing of its immunomodulation effect will be the object of interest of the immunologists of general practice and clinical research even in spite of some lacks in its characteristics.
authors.forename: A
authors.initials: A
authors.lastname: Mrázová
authors.forename: J
authors.initials: J
authors.lastname: Mráz
mesh_terms: D006801:Humans; D007111:Immunity, Cellular; D014165:Transfer Factor / Q000502:physiology / Q000627:therapeutic use*
chemical_list: D014165:Transfer Factor