Fetal macrosomia--pregnancy and delivery.
The authors have studied pregnancy, delivery and early neonatal status of macrosomic infants (> or = 4000 g) delivered between January 1, 1984, and December 31, 1992. The control group comprised age--and parity--matched pregnant women and their newborns weighing 3000 to 3999 g. From 9980 singleton pregnancies, 2021 (20.3%) macrosomics were delivered. The incidence of macrosomia was 16.7% in the primiparous group, 23.1% in the parity 2-4 group, and 28.2% in the multiparous group (parity > or = 5) (P < 0.001). The rates of macrosomic infants for pregnant adolescents (aged < or = 19 years), pregnant women aged 20-34 years and old pregnant women (> or = 35 years) were 12.0%, 20.6% and 21.5%, respectively (P < 0.001). Macrosomia was not influenced by occupation and antenatal visits (P > 0.05). The rates of > or = 16 kg weight gain in the macrosomic and control groups were 36.2% (mean 14.30 +/- 4.66 kg) and 16.7% (mean 12.18 +/- 4.82 kg), respectively (t = 12.05; P < 0.001). Of 546 pregnant women with fetal macrosomia subjected to oral GT testing, glucose intolerance was found in 20.0% and gestational diabetes in 4.8%. The rates of glucose intolerance and gestational diabetes in 259 control subjects were 13.9% and 2.3%, respectively (P < 0.05). Light (index 1-4) and moderate (index 5-7) forms of EPH gestosis were more common in the macrosomic group, whereas no difference was observed for severe forms (index > or = 8) between the groups (P > 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
Mikulandra
F
F
Department of scientific research, Medical center of Sibenik, Croatia.
Stojnić
E
E
Perisa
M
M
Merlak
I
I
Sikić
D
D
Zenić
N
N
D000293:Adolescent; D000328:Adult; D001034:Apgar Score; D001720:Birth Injuries / Q000401:mortality / Q000503:physiopathology; D001724:Birth Weight; D005113:Extraction, Obstetrical; D005260:Female; D005313:Fetal Death; D005320:Fetal Macrosomia / Q000401:mortality / Q000503:physiopathology*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008423:Maternal Age; D007744:Obstetric Labor Complications / Q000401:mortality / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000401:mortality / Q000503:physiopathology*; D012307:Risk Factors