title: [Osteosclerosis of the vertebrae in radiological diagnosis and its pathomechanism].
abstract: Primarily osteosclerosis is detected in secondary hyperparathyroidism, renal osteodystrophia and some renal tubular disorders. As mentioned, the sclerosis of vertebral body is often prominent in the regions adjacent to the endplates the typical "rugger-jersey-spine". In our study osteosclerosis was detected in about 10% of the patients with renal osteodystrophia. A still unknown defect in vitamin D-metabolism and a increased avidity of the skeleton for calcium may also involved. The result of this accumulation of steroid is a net increase of bone tissue, with or not mineralization. Conventional radiography is the method of choice in detecting typical features.
authors.affiliation: Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Universität Berlin.
authors.forename: J
authors.initials: J
authors.lastname: Mäurer
authors.forename: P
authors.initials: P
authors.lastname: Uhrmeister
authors.forename: E
authors.initials: E
authors.lastname: Dühmke
authors.forename: R
authors.initials: R
authors.lastname: Felix
mesh_terms: D000328:Adult; D000368:Aged; D002118:Calcium / Q000378:metabolism; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000503:physiopathology; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010026:Osteosclerosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014807:Vitamin D / Q000378:metabolism
chemical_list: D014807:Vitamin D; D002118:Calcium
vernacular_title: Die Osteosklerose der Wirbelkörper in der radiologischen Diagnostik und ihr Pathomechanismus.