[The experimental efficacy of vaccination with a recombinant yeast vaccine against hepatitis B in combination with immunomodulators].
Experiments in BALB/c mice were carried out to study a number of immunomodulators in combination with vaccination using a recombinant yeast hepatitis B vaccine. The use of poludan, ridostine, amixine, larifan, myekonide significantly enhanced specific antibody production and at least doubled cell-mediated immune response by 14 and 28 days postvaccination. The above-mentioned immunomodulators are planned to be used in vaccination with the recombinant yeast vaccine against hepatitis B.
Barinskiĭ
I F
IF
Lycheva
I A
IA
Suetina
I A
IA
Posevaia
T A
TA
Granovskiĭ
N N
NN
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D004353:Drug Evaluation, Preclinical; D005657:Fungal Vaccines / Q000276:immunology*; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000276:immunology*; D007114:Immunization / Q000379:methods; D051379:Mice; D008807:Mice, Inbred BALB C; D013997:Time Factors; D014614:Vaccines, Synthetic / Q000276:immunology*; D015003:Yeasts / Q000276:immunology*
D000276:Adjuvants, Immunologic; D005657:Fungal Vaccines; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic
Effektivnost' v éksperimente vaktsinatsii rekombinantnoĭ drozhzhevoĭ vaktsinoĭ protiv gepatita B v sochetanii s immunomoduliatorami.