title: Production of additional squalestatin analogues by directed biosynthesis.
authors.affiliation: Department of Natural Products Discovery, Glaxo Group Research Ltd., Greenford, Middlesex, U.K.
authors.forename: R J
authors.initials: RJ
authors.lastname: Cannell
authors.forename: M J
authors.initials: MJ
authors.lastname: Dawson
authors.forename: R S
authors.initials: RS
authors.lastname: Hale
authors.forename: R M
authors.initials: RM
authors.lastname: Hall
authors.forename: D
authors.initials: D
authors.lastname: Noble
authors.forename: S
authors.initials: S
authors.lastname: Lynn
authors.forename: N L
authors.initials: NL
authors.lastname: Taylor
mesh_terms: D000818:Animals; D001643:Bridged Bicyclo Compounds / Q000302:isolation & purification / Q000494:pharmacology; D019086:Bridged Bicyclo Compounds, Heterocyclic; D002851:Chromatography, High Pressure Liquid; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors*; D005285:Fermentation; D051381:Rats; D014233:Tricarboxylic Acids / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D014233:Tricarboxylic Acids; C075117:squalestatin 1; D013186:Farnesyl-Diphosphate Farnesyltransferase