Acquisition and storage of inorganic iron and hemin by the yersiniae.
Pathogenic Yersinia express a complex array of iron-regulated functions and possess mechanisms for inorganic iron and hemin acquisition. These include a unique temperature-regulated hemin storage system, high-affinity transport processes for hemin and inorganic iron, and an iron-responsive regulatory system controlling gene expression. The genetic organization of these systems illuminates several aspects of iron metabolism in the yersiniae.
Perry
R D
RD
Dept of Microbiology and Immunology, University of Kentucky, Lexington 40536-0084.
D001483:Base Sequence; D005798:Genes, Bacterial; D006427:Hemin / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D008969:Molecular Sequence Data; D015007:Yersinia / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity
D006427:Hemin; D007501:Iron