title: [Estrogens, progestins and cancer of the endometrium].
abstract: The presence of estrogens alone increases the risk of cancer of the endometrium. The risk increases with dosage and length of administration. Estrogens have a promoting rather than an initiating role since the risk progressively disappears after stopping treatment. Hormone-induced cancers have a better prognosis than spontaneous cancers. The association of progesterone or a progestogen obviates this risk. Prescription of oestrogens after treatment of cancer of the endometrium is non longer strictly contraindicated. Each case should be considered independently.
authors.affiliation: Service de gynécologie obstétrique, hôpital Arnaud-de-Villeneuve, Montpellier.
authors.forename: F
authors.initials: F
authors.lastname: Laffargue
authors.forename: J P
authors.initials: JP
authors.lastname: Daures
mesh_terms: D000328:Adult; D016889:Endometrial Neoplasms / Q000139:chemically induced* / Q000517:prevention & control; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008593:Menopause / Q000187:drug effects; D011372:Progestins / Q000627:therapeutic use*; D012307:Risk Factors
chemical_list: D011372:Progestins
vernacular_title: Oestrogènes, progestatifs et cancer de l'endomètre.