title: Nonsurgical management of placenta percreta: a case report.
abstract: BACKGROUND
  Although placenta percreta is rare, its sequelae include potentially lethal hemorrhage and loss of reproductive function. Therapy directed toward control of life-threatening hemorrhage frequently includes emergency hysterectomy.
  
  
  METHODS
  A woman with placenta percreta, suspected clinically and documented radiographically, was treated nonsurgically. Following delivery, the placenta was left in situ and methotrexate chemotherapy was initiated to aid destruction of the trophoblastic tissue. Eight months later, hysteroscopy showed a normal uterine cavity with only a small area of calcification at the presumed implantation site. Two years later, the patient had a normal pregnancy and vaginal delivery.
  
  
  CONCLUSIONS
  Placenta percreta can be managed with preservation of the uterus, but careful follow-up may be required until the entire placenta has resorbed.
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, School of Medicine, Magee-Women's Hospital, Pennsylvania.
authors.forename: R S
authors.initials: RS
authors.lastname: Legro
authors.forename: F V
authors.initials: FV
authors.lastname: Price
authors.forename: L M
authors.initials: LM
authors.lastname: Hill
authors.forename: S N
authors.initials: SN
authors.lastname: Caritis
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D010921:Placenta Accreta / Q000188:drug therapy*; D011247:Pregnancy
chemical_list: D008727:Methotrexate