General anaesthesia vs sedation for minor gynaecological procedures--a comparative study.
Sedation using combined intravenous midazolam and fentanyl is a popular technique for minor gynaecological procedures. However, it is fraught with inconsistency in efficacy and has a greater tendency to perioperative oxygen desaturation. Fifty female ASA I patients scheduled for minor gynaecological procedures were given intravenous midazolam and fentanyl before surgery started. Intraoperative excessive movement that interfered with surgery and failure to maintain a patient airway were noted. Perioperative oxygen saturation was monitored with the pulse oximeter. In another group of 50 female ASA I patients, intravenous thiopentone was given and anaesthesia maintained with 67% nitrous oxide in 33% oxygen and 0.5% of isoflurane via a face mask. Results showed that 10% of the sedated patients had excessive movements that interfered with surgery, of which 6% needed a general anaesthetic. Twenty-two percent of the sedated patients needed maintenance of airway perioperatively. Perioperative oxygen desaturation was profound in incidence and degree in the sedated patients whereas no patient who received general anaesthesia desaturated. The perioperative incidence of desaturation in the sedated patients was 46%. Intraoperatively, 28% (p < 0.001) of the sedated patients had oxygen saturation in the range of 85 to 90% and 18% of them (p < 0.01) had oxygen saturation of less than 85%. Postoperatively 8% of the sedated patients had oxygen saturation of 85 to 90%. We conclude that general anaesthesia is more efficacious and safer than sedation in patients scheduled for minor gynaecological procedures. The same minimum standard of monitoring applied to general anaesthesia should be used for sedated patients.
Yeo
S W
SW
Department of Anaesthesia, Kandang Kerbau Hospital, Singapore.
Tay
D
D
Chong
J L
JL
Tan
T K
TK
D000293:Adolescent; D000328:Adult; D000768:Anesthesia, General; D016292:Procedural Sedation; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D005836:Genitalia, Female / Q000601:surgery*; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D007530:Isoflurane / Q000008:administration & dosage; D008874:Midazolam / Q000008:administration & dosage; D008875:Middle Aged; D013511:Minor Surgical Procedures; D009068:Movement; D009609:Nitrous Oxide / Q000008:administration & dosage; D010092:Oximetry; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood; D010102:Oxygen Inhalation Therapy; D013874:Thiopental / Q000008:administration & dosage
D007530:Isoflurane; D013874:Thiopental; D009609:Nitrous Oxide; D008874:Midazolam; D010100:Oxygen; D005283:Fentanyl