title: Airway compromise secondary to vascular compression in a neonate.
abstract: Respiratory distress in the neonate may be due to extrinsic tracheobronchial compression. We recently observed a neonate with left mainstem bronchus obstruction resulting in respiratory distress and mediastinal shift. Initial management required intubation and positive pressure ventilation. Bronchoscopic evaluation demonstrated compression of the proximal left main bronchus. The distal bronchus appeared normal. Bronchography, echocardiography and an MRI of the chest confirmed proximal compression of the bronchus and suggested that the cause was an aneurysmal left pulmonary artery and patent ductus arteriosus. With medical therapy there was resolution of the bronchial compression. Re-evaluation by bronchoscopy and echocardiography revealed a normal left main stem bronchus, a normal left pulmonary artery and a closed ductus arteriosus. This clinical scenario suggests that transient pulmonary hypertension may result in significant airway compression due to the proximity of the left main stem bronchus to the left pulmonary artery.
authors.affiliation: Division of Head and Neck Surgery, University of California, San Diego 92123.
authors.forename: M H
authors.initials: MH
authors.lastname: Terris
authors.forename: R D
authors.initials: RD
authors.lastname: Mainwaring
authors.forename: S M
authors.initials: SM
authors.lastname: Pransky
mesh_terms: D000783:Aneurysm / Q000150:complications / Q000151:congenital*; D001982:Bronchial Diseases / Q000151:congenital / Q000209:etiology; D003251:Constriction, Pathologic; D004374:Ductus Arteriosus, Patent / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011651:Pulmonary Artery / Q000473:pathology; D012131:Respiratory Insufficiency / Q000209:etiology*