title: The effects of ninjinyoeito on human vascular endothelial cells.
abstract: The effects of Ninjinyoeito on endothelial cells from a human umbilical vein were examined. As a result, the maximum cell density obtained after the addition of Ninjinyoeito was found to be 400 ng/ml, and its inhibitory effect on the development of endothelial injury was also observed. In addition, the levels of LDH and Al-p, which are parameters decreasing with aging, were significantly high. Judging from these results, Ninjinyoeito presumably exerts an anti-aging effect by inhibiting the metabolic aging of cells.
authors.affiliation: Kanagawa Rehabilitation Institute, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Uchiyama
authors.forename: S
authors.initials: S
authors.lastname: Nakajima
authors.forename: K
authors.initials: K
authors.lastname: Yoshida
authors.forename: H
authors.initials: H
authors.lastname: Mizukawa
authors.forename: E
authors.initials: E
authors.lastname: Haruki
mesh_terms: D002452:Cell Count / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D016922:Cellular Senescence / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D014471:Umbilical Veins
chemical_list: D004365:Drugs, Chinese Herbal; C072867:ren-shen-yang-rong-tang; D007770:L-Lactate Dehydrogenase