title: [Digoxin content in blood lipids of children, athletes, sports ground attendants and residents after content with dioxin-containing surface slag (Kieselrot)].
abstract: In 1991 it was discovered, that a large number of sporting grounds and playgrounds in Germany were covered with a waste slag material from a former copper smelter located at Marsberg, Germany. This material was found to contain high levels of PCDD/F ranging up to 100,000 TE/kg. The objective of the present study was to assess whether subjects sporting on such grounds had elevated levels of PCDD/F in blood. PCDD/F in blood fat was used as an indicator of the PCDD/F body burden. Additionally, six children and seven residents of a contaminated sporting and playground were examined. Generally, the levels of PCDD/F in blood fat were in the range of background levels in all subjects. Taking into account the effect of age, slightly elevated blood levels of PCDD/F were detected in children. The results show that the bioavailability of PCDD/F in the slag material is very low. However, from the preventive point of view children who might ingest slag material by hand-to-mouth-activities, should not play on such contaminated playgrounds.
authors.affiliation: Hygiene-Institut des Ruhrgebiets, Institut für Umwelthygiene und Umweltmedizin, Gelsenkirchen.
authors.forename: U
authors.initials: U
authors.lastname: Ewers
authors.forename: J
authors.initials: J
authors.lastname: Wittsiepe
authors.forename: P
authors.initials: P
authors.lastname: Schrey
authors.forename: M
authors.initials: M
authors.lastname: Exner
authors.forename: F
authors.initials: F
authors.lastname: Selenka
authors.forename: M
authors.initials: M
authors.lastname: Hofbauer
authors.forename: D
authors.initials: D
authors.lastname: Schmeer
authors.forename: L
authors.initials: L
authors.lastname: Holwitt
authors.forename: R
authors.initials: R
authors.lastname: Eck
mesh_terms: D000293:Adolescent; D000328:Adult; D001572:Benzofurans / Q000493:pharmacokinetics; D002648:Child; D004147:Dioxins / Q000493:pharmacokinetics*; D004781:Environmental Exposure / Q000009:adverse effects; D004784:Environmental Monitoring; D005260:Female; D006256:Hazardous Waste / Q000032:analysis*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010988:Play and Playthings; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D011108:Polymers / Q000493:pharmacokinetics; D012016:Reference Values; D012989:Soil Pollutants / Q000032:analysis*; D013177:Sports / Q000502:physiology*
chemical_list: D001572:Benzofurans; D004147:Dioxins; D006256:Hazardous Waste; D008055:Lipids; D000072317:Polychlorinated Dibenzodioxins; D011108:Polymers; D012989:Soil Pollutants; C016068:polychlorodibenzofuran
vernacular_title: Dioxingehalte im Blutfett von Kindern, Sportlern, Platzwarten und Anwohnern nach Kontakt mit dioxinhaltigen Tennenflächen (Kieselrot).