title: [Nasal mucociliary transport time and ciliary beat frequency in healthy probands and patients with sinusitis].
abstract: The mucociliary system is an important defence mechanism of the respiratory tract. It depends on the interaction between cilia and mucus. To evaluate the value of the saccharin test and a photoelectrical in-vitro method for measurement of ciliary beat frequency for clinical routine diagnosis, we studied twenty patients suffering from acute sinusitis (aged 19-64) and twenty healthy non-smokers (aged 19-50). The nasal mucociliary transport time of saccharin was significantly higher (p < or = 0.01) and the ciliary beat frequency was significantly lower (p < or = 0.001) in patients with acute sinusitis, compared to normals. There was no correlation between nasal mucociliary transport time and ciliary beat frequency in patients with acute sinusitis (r = 0.21) and in healthy non-smokers (r = -0.37). Nasal mucociliary transport time of saccharin and photoelectrical in-vitro method for measurement of ciliary beat frequency measure different aspects of the mucociliary system. They are complementary. Both methods can be carried out together in routine diagnosis.
authors.affiliation: Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Ernst-Moritz-Arndt-Universität Greifswald.
authors.forename: G
authors.initials: G
authors.lastname: Karnitzki
authors.forename: G
authors.initials: G
authors.lastname: Mlynski
authors.forename: B
authors.initials: B
authors.lastname: Mlynski
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation; D008297:Male; D008858:Microscopy, Phase-Contrast / Q000295:instrumentation; D008875:Middle Aged; D009079:Mucociliary Clearance / Q000502:physiology*; D012016:Reference Values; D012439:Saccharin; D012852:Sinusitis / Q000503:physiopathology*; D013649:Taste / Q000502:physiology
chemical_list: D012439:Saccharin
vernacular_title: Nasale mukoziliare Transportzeit und ziliare Schlagfrequenz bei Gesunden und Sinusitispatienten.