Criminality and platelet monoamine oxidase activity in former juvenile delinquents as adults.
Platelet monoamine oxidase (MAO) activity was estimated in 70 former delinquent boys and 40 controls now aged 38-46 years. Platelet MAO activity was compared with their early criminal behaviour (before the age of 15) and their late registered criminality from the age of 15). Mean platelet MAO activity in subjects with both early and late criminality was significantly lower than that in former delinquents without late criminality. There was no significant difference in mean platelet MAO activity between controls and delinquents with early but no late criminality. When delinquents with early criminality were divided into a low and a high MAO group, the relative risk to be registered for late criminality was about 3.1 times higher for the subjects in the low MAO group. Thus, individuals with low platelet MAO activity run an increased risk of continued criminal behaviour.
Alm
P O
PO
Department of Social and Forensic Psychiatry, Karolinska Institute, Huddinge, Sweden.
Alm
M
M
Humble
K
K
Leppert
J
J
Sörensen
S
S
Lidberg
L
L
Oreland
L
L
D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000201:enzymology* / Q000523:psychology; D001792:Blood Platelets / Q000201:enzymology*; D002648:Child; D015331:Cohort Studies; D003415:Crime; D005500:Follow-Up Studies; D006801:Humans; D007604:Juvenile Delinquency / Q000523:psychology; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood*; D010553:Personality Development; D012008:Recurrence; D012307:Risk Factors
D008995:Monoamine Oxidase