Effects of hormones on chemotaxis in Tetrahymena: investigations on receptor memory.
The peptide type hormones such as insulin and adenocorticotropic hormone (ACTH) have a positive chemoattractant effect on Tetrahymena. Non-hormone protein-sulphate provoked negative chemoattraction. Of the amino acid type hormones, serotonin produced negative, and the histamine and di-iodotyrosine induced positive chemotactic effects. The first encounter with these molecules may modify the chemotactic behaviour of the progeny cells. In a significant number of cases there was a different response after repeated encounters of cells and hormones.
Köhidai
L
L
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
Karsa
J
J
Csaba
G
G
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D002633:Chemotaxis / Q000187:drug effects* / Q000502:physiology; D006632:Histamine / Q000494:pharmacology; D006728:Hormones / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology; D007470:Monoiodotyrosine / Q000494:pharmacology; D011479:Protamines / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology; D013769:Tetrahymena pyriformis / Q000187:drug effects / Q000502:physiology*
D006728:Hormones; D007328:Insulin; D011479:Protamines; D012701:Serotonin; D006632:Histamine; D000324:Adrenocorticotropic Hormone; D007470:Monoiodotyrosine