title: Management of patients with chronic asthma: controversies and future directions.
abstract: Hospitalizations and mortality due to asthma have increased, despite advances in asthma treatment. Several aspects of the management of patients with chronic asthma are under discussion in efforts to address this problem. Therapeutic interventions, including the use of theophylline, corticosteroids, and beta 2-agonist chronotherapy, will be reviewed, with the goal of defining ways of attaining the optimal response when using pharmacologic and nonpharmacologic regimens in the treatment of patients with chronic asthma.
authors.affiliation: National Jewish Center of Immunology and Respiratory Medicine, Denver, Colorado.
authors.forename: R J
authors.initials: RJ
authors.lastname: Martin
mesh_terms: D001249:Asthma / Q000628:therapy*; D002908:Chronic Disease; D004358:Drug Therapy / Q000639:trends; D005544:Forecasting; D006801:Humans