title: Early failures among 14,009 cemented and 1,326 uncemented prostheses for primary coxarthrosis. The Norwegian Arthroplasty Register, 1987-1992.
abstract: In the Norwegian Arthroplasty Register, 15,335 primary total hip replacements (THR) in patients with primary arthrosis were followed for 0-5.4 years. The Kaplan-Meier estimate of cumulative failure (revision) after 4.5 years was 2.7 percent for cemented THR, compared to 6.5 percent for uncemented. In patients under 65 years the cumulative revisions for cemented and uncemented THR were 3.3 and 7.9 percent. For the acetabular components, the cumulative failures were 0.6 percent for cemented and 1.7 percent for uncemented, and for femoral components 1.7 and 3.9 percent after 4.5 years. Adjusting for age and sex using a Cox regression model, 2 times higher rates of failure were found comparing uncemented to cemented THR. The results for uncemented prostheses were more unfavorable in young patients. In men and women under 60, the revision rates were increased 6 and 3 times, respectively, for patients with uncemented THR compared to those with cemented THR. Restriction of the end-point to revision for aseptic loosening gave results similar to the over-all results. No difference between cemented and uncemented THR was seen for revisions due to infection, whereas the most unfavorable results for uncemented THR were seen when revisions due to causes other than infection and aseptic loosening were considered.
authors.affiliation: University of Bergen, Department of Orthopedics and Traumatology, Haukeland Hospital, Norway.
authors.forename: L I
authors.initials: LI
authors.lastname: Havelin
authors.forename: B
authors.initials: B
authors.lastname: Espehaug
authors.forename: S E
authors.initials: SE
authors.lastname: Vollset
authors.forename: L B
authors.initials: LB
authors.lastname: Engesaeter
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001843:Bone Cements / Q000627:therapeutic use*; D002484:Cementation; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009664:Norway; D015207:Osteoarthritis, Hip / Q000601:surgery*; D016016:Proportional Hazards Models; D011475:Prosthesis Failure; D012042:Registries; D012044:Regression Analysis; D012086:Reoperation; D012737:Sex Factors; D013997:Time Factors
chemical_list: D001843:Bone Cements