[Norepinephrine content in various brain structures and activity of alcohol dehydrogenase and aldehyde dehydrogenase in blood serum of rats with varying predisposition to ethanol consumption].
Noradrenaline content in hypothalamus, midbrain and new cortex as well as the activity of alcohol- and aldehyde dehydrogenase in the blood serum of rats with different alcohol motivation were studied. It is shown that rats, which prefer ethanol, are characterized by the lower content of noradrenaline in hypothalamus, midbrain and new cortex as compared to animals which prefer water. It is found out that alcohol motivation in rats correlates with high activity of blood serum aldehyde dehydrogenase. No reliable relation between ethanol preferring and activity of blood alcohol dehydrogenase was revealed.
Kharchenko
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NK
Sinitskiĭ
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D000426:Alcohol Dehydrogenase / Q000097:blood*; D000428:Alcohol Drinking / Q000378:metabolism* / Q000523:psychology; D000444:Aldehyde Dehydrogenase / Q000097:blood*; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002540:Cerebral Cortex / Q000378:metabolism; D002755:Choice Behavior / Q000502:physiology; D004837:Epinephrine / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism; D008297:Male; D008636:Mesencephalon / Q000378:metabolism; D009042:Motivation; D051381:Rats
D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase; D004837:Epinephrine
Soderzhanie noradrenalina v nekotorykh strukturakh mozga i aktivnost' alkogol'degidrogenazy i al'degiddegidrogenazy syvorotki krovi krys s razlichnoĭ predraspolozhennost'iu k potrebleniiu étanola.