Preparation of 6(1),6n-di-O-(tert-butyldimethylsilyl)-cyclomalto-octaoses.
Four positional isomers of 6(1),6n-di-O-(tert-butyldimethylsilyl)- cyclomalto-octaose (n = 2-5) were prepared by reaction of cyclomalto-octaose (1, cG8) with tert-butyldimethylsilyl chloride in pyridine, and were isolated by high-performance liquid chromatography. The regiochemical determination of those positional isomers was performed by comparison with authentic compounds, prepared from 6(1),6n-di-O-trityl-cG8s (n = 2-5).
Tanimoto
T
T
Faculty of Pharmaceutical Sciences, Mukogawa Women's University, Nishinomiya, Japan.
Sakaki
T
T
Iwanaga
T
T
Koizumi
K
K
D002240:Carbohydrate Sequence; D003505:Cyclodextrins / Q000138:chemical synthesis*; D007536:Isomerism; D008969:Molecular Sequence Data; D017646:Organosilicon Compounds / Q000138:chemical synthesis
D003505:Cyclodextrins; D017646:Organosilicon Compounds; C009660:t-butyldimethylsilyl compounds