[Pharmacology of estrogens used in the treatment of menopause].
Numerous compounds with estrogenic activity are available to treat menopause. The main ones are oestradiol, administered by various routes, and equine estrogens which are taken orally. These compounds differ from each other by their chemical structure, metabolism and kinetics; the metabolic impact of these drugs especially on the liver depends on these parameters. All estrogens are potent, active, and capable of treating effectively the short and long term manifestations of menopause. Their metabolic safety according to the route of administration remains opened to discussion.
Basdevant
A
A
Service de médecine et nutrition, Hôtel-Dieu, Paris.
Panotopoulos
G
G
D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology; D004967:Estrogens / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008593:Menopause / Q000187:drug effects*; D008875:Middle Aged
D004967:Estrogens; D004958:Estradiol
Pharmacologie des oestrogènes utilisés pour le traitement de la ménopause.