title: [Cardiotoxicity of 5-fluorouracil. Clinical picture of 4 cases and a prevention proposal].
abstract: 5-fluoro-uracil (5-FU) cardiotoxicity has been often reported during chemotherapy. We collect four atypical cases of cardiac side effects in patients treated by 5-FU for head and neck tumors. We review the literature about the subject, and we propose criteria to detect patients with a high risk level, and to prevent this adverse effect incidence.
authors.affiliation: Service de Radiothérapie, CHU de Poitiers.
authors.forename: H
authors.initials: H
authors.lastname: Bourgeois
authors.forename: M C
authors.initials: MC
authors.lastname: Perault
authors.forename: P
authors.initials: P
authors.lastname: Raud-Raynier
authors.forename: S
authors.initials: S
authors.lastname: Favrelière
authors.forename: A
authors.initials: A
authors.lastname: Daban
authors.forename: B
authors.initials: B
authors.lastname: Vandel
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000139:chemically induced; D005472:Fluorouracil / Q000009:adverse effects*; D006331:Heart Diseases / Q000139:chemically induced* / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D005472:Fluorouracil
vernacular_title: Cardiotoxicité du 5-fluoro-uracile. Tableaux cliniques à propos de 4 cas et proposition de prévention.