[Present and future choice of pharmaceutical forms for intravaginal administration. II. Barrier systems and vaginal rings].
In part I of this review, various vaginal products for local and systemic treatment have been described and discussed. Part II is reserved to other intravaginal contraceptive systems. Some devices as diaphragms, sponges, ... have a mechanical contraceptive advantage associated or not with a spermicidal activity and can or cannot protect against venereal diseases. Other devices like intravaginal rings allow a long-acting and controlled release of contraceptive hormones and it is quite possible that they replace orale contraceptive dosage forms. Various approaches in designs, safety, effectiveness, inconvenience and advantages are discussed.
Guyot
M
M
Laboratoire de pharmacie galénique et biopharmacie, Université de Bordeaux II, France.
Fawaz
F
F
D000282:Administration, Intravaginal; D003271:Contraceptive Agents, Female / Q000008:administration & dosage* / Q000009:adverse effects; D003274:Contraceptive Devices, Female / Q000009:adverse effects; D005260:Female; D006801:Humans; D011372:Progestins / Q000008:administration & dosage
D003271:Contraceptive Agents, Female; D011372:Progestins
Le choix actuel et futur des formes pharmaceutiques administrées par voie intravaginale. II. Les systèmes barrière et les anneaux vaginaux.