Repeated and persistent infection with Chlamydia and the development of chronic inflammation and disease.
Chlamydia trachomatis is an important human pathogen that mediates disease processes capable of inflicting permanent damage. Aggressive inflammatory responses to repeated infections, and to a persistent form of this intracellular bacterium, are thought to initiate the pathogenic events that lead to the debilitating sequelae of blinding trachoma and infertility.
Beatty
W L
WL
Dept of Medical Microbiology and Immunology, University of Wisconsin, Madison 53706.
Byrne
G I
GI
Morrison
R P
RP
D002690:Chlamydia Infections / Q000276:immunology* / Q000382:microbiology / Q000473:pathology*; D002692:Chlamydia trachomatis / Q000254:growth & development / Q000276:immunology / Q000378:metabolism*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007246:Infertility / Q000209:etiology; D007371:Interferon-gamma / Q000276:immunology; D008297:Male; D012008:Recurrence; D014141:Trachoma / Q000276:immunology* / Q000473:pathology
D007371:Interferon-gamma