Orthodeoxia in amiodarone-induced acute reversible pulmonary damage.
A case of acute reversible pulmonary damage from amiodarone is described. Pulmonary infiltrates had a basal predominance. The histopathologic picture was that of acute alveolitis. Orthodeoxia was evident on blood gas analysis; the PaO2 was 73 mm Hg on recumbency, and the PaO2 was 57 mm Hg in the upright position. Partial arterial resaturation was evident on exercise (PaO2, 64 mm Hg).
Papiris
S A
SA
Department of Medicine, University of Ioannina Medical School, Greece.
Maniati
M A
MA
Manoussakis
M N
MN
Constantopoulos
S H
SH
D000638:Amiodarone / Q000009:adverse effects* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D001784:Blood Gas Analysis; D006801:Humans; D008171:Lung Diseases / Q000097:blood / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D011187:Posture / Q000502:physiology*
D000638:Amiodarone; D010100:Oxygen