Fluorescence in situ hybridization in cancer and radiation biology.
This review describes molecular cytogenetic approaches to genetic analysis including fluorescence in situ hybridization, primed in situ labeling and comparative genomic hybridization. It also summarizes the applications of this technology to physical mapping, cancer diagnosis and prognostication and in radiation biology.
Gray
J W
JW
Department of Laboratory Medicine and Radiation Oncology, University of California, San Francisco 94143.
Pinkel
D
D
Brown
J M
JM
D000818:Animals; D002874:Chromosome Mapping; D015342:DNA Probes; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008853:Microscopy / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics; D011853:Radiobiology / Q000379:methods*
D015342:DNA Probes