[Cardiotoxicity of 5-fluorouracil. Clinical picture of 4 cases and a prevention proposal].
5-fluoro-uracil (5-FU) cardiotoxicity has been often reported during chemotherapy. We collect four atypical cases of cardiac side effects in patients treated by 5-FU for head and neck tumors. We review the literature about the subject, and we propose criteria to detect patients with a high risk level, and to prevent this adverse effect incidence.
Bourgeois
H
H
Service de Radiothérapie, CHU de Poitiers.
Perault
M C
MC
Raud-Raynier
P
P
Favrelière
S
S
Daban
A
A
Vandel
B
B
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000139:chemically induced; D005472:Fluorouracil / Q000009:adverse effects*; D006331:Heart Diseases / Q000139:chemically induced* / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged
D005472:Fluorouracil
Cardiotoxicité du 5-fluoro-uracile. Tableaux cliniques à propos de 4 cas et proposition de prévention.