[Successful combination therapy in bronchial asthma. Anti-obstructive and anti-inflammatory treatment].
METHODS
In a post-marketing surveillance study, patient data were documented with the aim of assessing the effect of a combination of both anti-inflammatory and bronchodilatory treatment with inhaled beclomethasone dipropionate and a sustained-release theophylline preparation. A total of 2,166 patients with mild-to-moderate bronchial asthma (FEV1 about 60%) were included in the multicenter open study.


RESULTS
It was found that treatment with inhaled glucocorticoid and sustained-release theophylline resulted in a clear improvement in symptom scores. More than 90% of the physicians and patients rated the treatment "very good" or "good". Only 4.6% of the participants had side effects.


CONCLUSIONS
It may be concluded that combination therapy with inhaled glucocorticoid and sustained release theophylline is a safe and effective form of treatment of mild-to-moderate asthma.
Thomsen
M
M
Byk Gulden, Lomberg Chemische Fabrik GmbH, Konstanz.
Zahn
T
T
D000280:Administration, Inhalation; D000284:Administration, Oral; D001249:Asthma / Q000188:drug therapy*; D001507:Beclomethasone / Q000008:administration & dosage* / Q000009:adverse effects; D004359:Drug Therapy, Combination; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011358:Product Surveillance, Postmarketing; D013806:Theophylline / Q000008:administration & dosage* / Q000009:adverse effects
D013806:Theophylline; D001507:Beclomethasone
Erfolgreiche Kombinationstherapie bei Asthma bronchiale. Antiobstruktive und antiinflammatorische Behandlung.