title: Age-related changes in the human lens: a comparison of Scheimpflug photography and lens density index.
abstract: Two quantitative techniques, Scheimpflug photography and the lens density index (LDI), were used to measure lens density in 52 patients. In the Scheimpflug technique, a digitized slitlamp camera provides peak and average nuclear density based on a densitometric analysis of the lens nucleus. The LDI is a psychophysical measurement of the difference between retinal scotopic thresholds for two wave-lengths of light. Both the Scheimpflug technique and LDI revealed an age-related increase in lens density. Peak and average nuclear density were highly correlated with the LDI.
authors.affiliation: Shiley Eye Center, University of California, San Diego.
authors.forename: M E
authors.initials: ME
authors.lastname: Bosem
authors.forename: P A
authors.initials: PA
authors.lastname: Sample
authors.forename: G A
authors.initials: GA
authors.lastname: Martinez
authors.forename: M
authors.initials: M
authors.lastname: Lusky
authors.forename: R N
authors.initials: RN
authors.lastname: Weinreb
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D002386:Cataract / Q000503:physiopathology; D003720:Densitometry; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010781:Photography / Q000379:methods*; D011601:Psychophysics / Q000379:methods