title: Pulmonary hypertension associated with non-cirrhotic portal hypertension in systemic lupus erythematosus.
abstract: A case of non-cirrhotic portal hypertension in a patient with systemic lupus erythematosus, the first of our knowledge, is described. Severe pulmonary hypertension was associated with the portal hypertension and with markers of active auto-immunity. Pulmonary hypertension has not previously been associated with non-cirrhotic portal hypertension. The coexistence of vasculopathy of the portal and pulmonary vascular beds in this patient with active autoimmunity supports the postulate that portal-pulmonary hypertension may be immunologically mediated.
authors.affiliation: Rheumatic Diseases Unit, University of Cape Town, Observatory, South Africa.
authors.forename: D
authors.initials: D
authors.lastname: Woolf
authors.forename: M D
authors.initials: MD
authors.lastname: Voigt
authors.forename: K
authors.initials: K
authors.lastname: Jaskiewicz
authors.forename: A A
authors.initials: AA
authors.lastname: Kalla
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications* / Q000473:pathology; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000473:pathology