Other uses of surfactant.
Surfactant is found not only in the alveoli but in bronchioles and small airways. Along with its important role in surface-tension reduction in alveoli, surfactant has several other properties. Any condition characterized by mucus abnormality, mucociliary transport deficiency, airway obstruction, or bronchoalveolar collapse could potentially benefit from exogenous surfactant therapy. Anti-inflammatory and bactericidal properties of surfactant could provide additional benefit in a variety of diseases.
Brown
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Cardiopulmonary Medicine Department, Burroughs Wellcome Co., Research Triangle Park, North Carolina.
Pattishall
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EN
D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy*; D011663:Pulmonary Surfactants / Q000627:therapeutic use*
D011663:Pulmonary Surfactants