The etiology of early childhood diarrhea: a community study from Guinea-Bissau.
A potential enteropathogen was found in 50% of 1219 diarrheal episodes and 48% of 511 asymptomatic controls in a 1-year community study of childhood diarrhea. Rotavirus (3% of episodes), Cryptosporidium species (6%), and enteropathogenic Escherichia coli (EPEC) with EPEC adherence factor (4%) were more prevalent in cases than controls. Giardia lamblia (19%) was the most prevalent organism but was not associated with diarrhea. Enterotoxigenic E. coli (12%), Strongyloides stercoralis (5%), Shigella species (2%), Entamoeba histolytica trophozoites (2%), and Vibrio cholerae (1%) were found at nonsignificantly higher rates. Salmonella and Campylobacter species were more prevalent among control infants. Cryptosporidium species and sequential infections from other pathogens caused persistent diarrhea.
Mølbak
K
K
Epidemiology Research Unit, Statens Seruminstitut, Copenhagen, Denmark.
Wested
N
N
Højlyng
N
N
Scheutz
F
F
Gottschau
A
A
Aaby
P
P
da Silva
A P
AP
D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000150:complications / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006169:Guinea-Bissau / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012621:Seasons