title: [Predonation of autologous blood for up to 6 weeks in MAP solution prior to elective cardiac surgery].
abstract: Predonation of autologous blood was performed by means of MAP solution prior to elective cardiac surgery. MAP solution made it possible to store in the fashion of fluid for 6 weeks. In twenty-three patients, total 39 times, predonation of autologous blood was performed prior to the elective cardiac surgeries. The mean volume of predonated blood was 583 ml (400-1200 ml)/case with MAP solution and 165 ml (0-400 ml)/case with conventional CPD solution, and the mean volume of total predonated blood was 748 ml (400-1600 ml)/case. The mean of the maximum duration of MAP predonate blood storage in individual cases was 25 days. Homologous blood transfusion was required in three cases. Two of the three cases had total aortic arch replacement under selective cerebral perfusion and the remainder was 76 year-old-man with unstable angina. In twenty cases (87%), any homologous blood transfusion was not performed throughout their clinical course. Twenty (95%) cases of 21 conventional cardiopulmonary bypass operation cases, except two selective cerebral perfusion cases, could successfully avoid homologous blood transfusion. To conclude, by using MAP solution, it became possible to take the longer period for predonation prior to elective surgery up to 6 weeks, compared with that in conventional way of storage by means of CPD solution. It seems worth-while to use MAP solution in order to take more predonated blood for avoiding homologous blood transfusion in elective cardiac surgery as far as possible.
authors.affiliation: Department of Cardiovascular Surgery, Iwakuni National Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tanemoto
authors.forename: M
authors.initials: M
authors.lastname: Kuinose
authors.forename: Y
authors.initials: Y
authors.lastname: Kanaoka
mesh_terms: D000225:Adenine; D000328:Adult; D000368:Aged; D001793:Blood Preservation / Q000379:methods*; D001804:Blood Transfusion, Autologous; D006348:Cardiac Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008353:Mannitol; D008875:Middle Aged; D013997:Time Factors
chemical_list: C075774:MAP solution; D008353:Mannitol; D000225:Adenine