Pulse radiolysis study of the reactivity of chloramphenicol, diazepam and clonazepam with the electron and the hydroxyl radical.
Chloramphenicol (CAP), diazepam (DIAZ) and clonazepam (CLONA) have been irradiated in aqueous and methanolic solutions by pulsed electrons (Febetron 707). Spectra of the species formed by the attack of the solvated electron and of OH radical have been determined. The kinetics of reaction of CAP, DIAZ, and CLONA with the solvated electron have been measured. Reactions of radical-radical recombination have also been studied. All these reactions are limited by the diffusion of the reactive species.
Zeegers
F
F
UCL-Ecole de Pharmacie, Bruxelles.
Tilquin
B
B
Hickel
B
B
D002701:Chloramphenicol / Q000737:chemistry / Q000528:radiation effects*; D002998:Clonazepam / Q000737:chemistry / Q000528:radiation effects*; D003975:Diazepam / Q000737:chemistry / Q000528:radiation effects*; D004583:Electrons; D017665:Hydroxyl Radical; D011675:Pulse Radiolysis
D017665:Hydroxyl Radical; D002998:Clonazepam; D002701:Chloramphenicol; D003975:Diazepam