title: Use of CA 19-9 in the early detection of recurrences in colorectal cancer: comparison with CEA.
abstract: The serum levels of CA 19-9 were determined in the follow-up of 370 patients with colorectal cancer and compared with CEA. An increase in CA 19-9 preceded clinical diagnosis of recurrence in 25% of 72 patients. The mean time between the rise in CA 19-9 and clinical diagnosis of relapse was 3.7 months (median 3). Sensitivity of CA 19-9 in the early diagnosis of recurrence was much lower than that obtained for CEA (75%). Only 1 patient had elevated CA 19-9 levels and normal CEA.
authors.affiliation: Department of Clinical Biochemistry (Unit Cancer Research), Hospital Clínic i Provencial, Barcelona, Spain.
authors.forename: X
authors.initials: X
authors.lastname: Filella
authors.forename: R
authors.initials: R
authors.lastname: Molina
authors.forename: J M
authors.initials: JM
authors.lastname: Piqué
authors.forename: J C
authors.initials: JC
authors.lastname: Garcia-Valdecasas
authors.forename: J J
authors.initials: JJ
authors.lastname: Grau
authors.forename: F
authors.initials: F
authors.lastname: Novell
authors.forename: E
authors.initials: E
authors.lastname: Astudillo
authors.forename: A
authors.initials: A
authors.lastname: de Lacy
authors.forename: M
authors.initials: M
authors.lastname: Daniels
authors.forename: A M
authors.initials: AM
authors.lastname: Ballesta
mesh_terms: D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood*; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D006801:Humans; D012008:Recurrence
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen