title: [Genealogy and the clinical manifestations of familial hyperlipidemias types IIa and IIb].
abstract: To analyze genealogical and clinical characteristics of family hyperlipidemia type IIa and IIb, the author examined 40 probands and 179 close relatives. Blood lipid composition was investigated in 85 of them. Hyperlipidemia was found in 42 examinees which is in accordance with previous findings on this trait inheritance. Sons inherit hyperlipidemia from their fathers more frequently than daughters (60.0% against 40.0%, respectively). Coronary heart disease and other related clinical conditions arose more frequently in probands than in their relatives with hyperlipidemia though 10-year mortality in them was actually the same: 20.0 and 18.6%, respectively.
authors.forename: B M
authors.initials: BM
authors.lastname: Lipovetskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D005260:Female; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D015994:Incidence; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000453:epidemiology; D010375:Pedigree; D017678:Sex Distribution
chemical_list: D008055:Lipids; D008074:Lipoproteins
vernacular_title: O genealogii i klinicheskikh proiavleniiakh semeĭnoĭ giperlipidemii IIa i IIb tipov.