Pregnancy in a patient with eosinophilic granulomatosis of the lung: a case report.
BACKGROUND
There are three syndromes of histiocytosis X: eosinophilic granulomatosis of the lungs, Hand-Schüller-Christian disease, and Letterer-Siwe disease. Although there have been five case reports of Hand-Schüller-Christian disease in pregnancy, we found none describing pregnancy in patients with eosinophilic granulomatosis.


METHODS
We present a report of eosinophilic granulomatosis of the lungs in pregnancy. The patient's pregnancy was complicated by fetal growth retardation (FGR) and oligohydramnios, but resulted in the delivery of a healthy infant. Her pulmonary disease remained stable.


CONCLUSIONS
Pregnancy does not appear to exacerbate pulmonary eosinophilic granulomatosis. In this patient, pregnancy was complicated by FGR and oligohydramnios. This case report may be valuable in counseling patients with eosinophilic granulomatosis who are currently pregnant or contemplating pregnancy.
Mitra
A G
AG
Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill.
Turpin
S V
SV
Cefalo
R C
RC
D000328:Adult; D004803:Eosinophilic Granuloma / Q000150:complications; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D008171:Lung Diseases / Q000150:complications; D016104:Oligohydramnios / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications