Comparison of cognitive-behavior therapy and desipramine in the treatment of bulimia nervosa.
A comparison of cognitive-behavior therapy alone, desipramine alone, and cognitive-behavior therapy combined with desipramine was made in the treatment of bulimia nervosa. The study was terminated early with an N of only 7 subjects per condition because of a high drop-out rate and lack of positive response in the desipramine alone group compared to the other two groups. By this time it was also apparent that at posttreatment and at 6 months follow-up no benefit was being realized from combining cognitive-behavior therapy with desipramine.
Leitenberg
H
H
Department of Psychology, University of Vermont, Burlington 05405-0134.
Rosen
J C
JC
Wolf
J
J
Vara
L S
LS
Detzer
M J
MJ
Srebnik
D
D
D000293:Adolescent; D000328:Adult; D002032:Bulimia / Q000175:diagnosis / Q000188:drug therapy* / Q000628:therapy*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003131:Combined Modality Therapy; D003891:Desipramine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires
D003891:Desipramine