[Single or multiple balloon inflations in coronary angioplasty? Acute results and long-term angiography results of a prospective, randomized study of 300 patients].
325 coronary lesions in 300 consecutive patients (257 male, 43 female, 52 +/- 8 years) undergoing either single-vessel (n = 275) or double-vessel PTCA in two independent procedures (n = 25) were prospectively randomized to either one (group A, n = 167) or three (group B, n = 168) balloon inflations. By clinical and angiographic criteria, PTCA was successful in 295/325 lesions (90.8%) with no significant difference for group A (88.6%) and B (93.0%). Clinical follow-up was achieved in 92% of patients and angiographic follow-up was obtained in 261/295 (88.5%) successfully dilated lesions (A: 87.8%; B: 89.1%). Angiographic appearance of the dilated lesion (in % diameter stenosis) prior to PTCA, directly following PTCA and at follow-up was comparable for both groups: gr. A: 71 +/- 11%, 32 +/- 10%, and 40 +/- 21%; gr. B: 70 +/- 11%, 30 +/- 10%, and 40 +/- 20% resp. Restenosis rate was similar with 26.9% in group A and 29.8% in group B. The randomization had to be abandoned in 144/325 cases (44.3%) due to medical reasons. Results of only those lesions where it was possible to follow the initial randomization demonstrated a different pattern. Success rate was slightly higher in those with 3 inflations (gr. B1, n = 111) with 93.0% as compared to lesions with only one inflation (gr. A1, n = 70) with 88.6% success (p = ns). Subsequently, the initial angiographic result was slightly better for B1 with a reduction in diameter stenosis from 69 +/- 11% to 29 +/- 10% compared to A1 (71 +/- 11% and 32 +/- 10% resp.).(ABSTRACT TRUNCATED AT 250 WORDS)
vom Dahl
J
J
Medizinische Klinik I der RWTH Aachen.
Uebis
R
R
von Essen
R
R
Blome
R
R
Schmitz
E
E
Effert
S
S
Hanrath
P
P
D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D017225:Atherectomy, Coronary; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
Einmalige oder mehrmalige Balloninsufflation bei der Koronarangioplastie? Akutresultate und angiographische Langzeitergebnisse einer prospektiven, randomisierten Studie bei 300 Patienten.