title: The development of a Q-sort behavioral rating procedure for pediatric HIV patients.
abstract: Developed a Q-sort procedure to assess social, emotional, and motivational behavior associated with central nervous system disease among 180 HIV-infected pediatric patients. These ratings were factor analyzed and scales were derived based on the factor structure. Younger (M age = 1.03 years) patients with HIV-associated encephalopathy were rated as more apathetic and nonsocial in their behavior than nonencephalopathic younger patients. Older (M age = 7.8 years) encephalopathic patients had significantly higher scores on scales measuring depression, autism, and irritability compared to nonencephalopathic patients from this age group. A subgroup (26 patients) showed a significant decrease in these elevated scores after a 6-month course of AZT.
authors.affiliation: Pediatric Branch, National Cancer Institute, Bethesda, Maryland.
authors.forename: H A
authors.initials: HA
authors.lastname: Moss
authors.forename: P
authors.initials: P
authors.lastname: Brouwers
authors.forename: P L
authors.initials: PL
authors.lastname: Wolters
authors.forename: L
authors.initials: L
authors.lastname: Wiener
authors.forename: S
authors.initials: S
authors.lastname: Hersh
authors.forename: P A
authors.initials: PA
authors.lastname: Pizzo
mesh_terms: D015526:AIDS Dementia Complex / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology*; D006801:Humans; D007223:Infant; D008297:Male; D009042:Motivation; D011779:Q-Sort; D012803:Sick Role; D012919:Social Behavior; D015215:Zidovudine / Q000627:therapeutic use
chemical_list: D015215:Zidovudine