title: Terson's syndrome in a patient with acute promyelocytic leukemia on all-trans retinoic acid treatment.
abstract: The syndrome of vitreous hemorrhage in association with any form of intracranial bleeding is known as Terson's syndrome. Acute promyelocytic leukemia (APL) constitutes 5% to 15% of cases of acute nonlymphocytic leukemias, in which hemorrhagic diathesis often occurs and results in a rapid fatal outcome. In this report we describe a patient with APL who developed cerebral bleeding in association with bilateral subhyaloid and vitreous hemorrhages consistent with Terson's syndrome while she was on all-trans retinoic acid induction therapy.
authors.affiliation: Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
authors.forename: A M
authors.initials: AM
authors.lastname: Abu el-Asrar
authors.forename: A K
authors.initials: AK
authors.lastname: al-Momen
authors.forename: M S
authors.initials: MS
authors.lastname: Harakati
mesh_terms: D000328:Adult; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014212:Tretinoin / Q000009:adverse effects* / Q000627:therapeutic use; D014823:Vitreous Hemorrhage / Q000139:chemically induced*
chemical_list: D014212:Tretinoin