The 530 loop of 16S rRNA: a signal to EF-Tu?
The molecular mechanism of tRNA selection has remained elusive. Recent evidence, both biochemical and genetic, suggests the involvement of 'smart' ribosomes, that can signal the elongation factor Tu by way of conformational changes in ribosomal RNA.
Powers
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Sinsheimer Laboratories, University of California, Santa Cruz 95064.
Noller
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D008954:Models, Biological; D009690:Nucleic Acid Conformation; D010441:Peptide Chain Elongation, Translational; D010444:Peptide Elongation Factor Tu / Q000737:chemistry / Q000378:metabolism*; D011487:Protein Conformation; D012336:RNA, Ribosomal, 16S / Q000737:chemistry / Q000378:metabolism*; D012343:RNA, Transfer / Q000378:metabolism; D012269:Ribosomal Proteins / Q000235:genetics
D012336:RNA, Ribosomal, 16S; D012269:Ribosomal Proteins; C034212:ribosomal protein S12; D012343:RNA, Transfer; D010444:Peptide Elongation Factor Tu