Hypophyseal non-Hodgkin's lymphoma presenting with clinical panhypopituitarism successfully treated with chemotherapy.
A patient is described with a testicular Non-Hodgkin's Lymphoma (NHL) presenting with panhypopituitarism caused by a hypophyseal localization. A 67Gallium scintigraphy showed avid uptake in the hypophyseal region. Obviously 67Gallium could reach the tumor, by the intravenous route, which was the reason to treat the patient with intravenous chemotherapy. A complete remission was induced, which seems to be lasting (+25 months). As far as we know this is the first report of panhypopituitarism caused by a hypophyseal NHL in the hypophysis and successfully treated by intravenous chemotherapy.
Jonkhoff
A R
AR
Department of Hematology, Free University Hospital, Amsterdam, The Netherlands.
Huijgens
P C
PC
Schreuder
W O
WO
Teule
G J
GJ
Heimans
J J
JJ
D000368:Aged; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D011877:Radionuclide Imaging