title: Germ cell tumors of the ovary arising after dermoid cyst resection: a long-term follow-up study.
abstract: OBJECTIVE
  To study the long-term ovarian neoplastic consequences of resection of a dermoid cyst.
  
  
  METHODS
  The study population comprised 99 patients who were operated on for an ovarian dermoid cyst. Follow-up information was obtained for 91 women for a mean period of 5.06 +/- 2.46 years.
  
  
  RESULTS
  Of the 99 women, 18 had bilateral dermoid cysts. Multiple dermoid cysts in a single ovary were found in nine of the women with bilateral cysts and in one of the remaining patients. Two patients developed malignant germ cell tumors, and three developed a recurrent dermoid cyst in an ovary from which a dermoid cyst had previously been extracted. Bilateral or multiple ovarian dermoid cysts were present at the initial operation in four (80%) of these patients.
  
  
  CONCLUSIONS
  Women with bilateral or multiple dermoid cysts may include a subgroup of patients with a greater tendency to develop future ovarian germ cell neoplasms.
authors.affiliation: Department of Obstetrics and Gynecology, Hadassa University Hospital, Mt. Scopus, Jerusalem, Israel.
authors.forename: E Y
authors.initials: EY
authors.lastname: Anteby
authors.forename: M
authors.initials: M
authors.lastname: Ron
authors.forename: A
authors.initials: A
authors.lastname: Revel
authors.forename: S
authors.initials: S
authors.lastname: Shimonovitz
authors.forename: I
authors.initials: I
authors.lastname: Ariel
authors.forename: A
authors.initials: A
authors.lastname: Hurwitz
mesh_terms: D000328:Adult; D003884:Dermoid Cyst / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D018237:Germinoma / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery*; D013997:Time Factors