Misleading hepatitis C serology following administration of intravenous immunoglobulin.
Intravenous immunoglobulin (IVIG) is a blood derivative that is being evaluated for the prevention and treatment of numerous disorders. Recent studies have suggested beneficial effects from the prophylactic administration of IVIG to very-low-birth-weight neonates. A disadvantage of such therapy is misleading infectious disease serologic assays following administration of IVIG. The authors report a recent case in their neonatal intensive care unit of a 24-week gestational age girl with a misleading positive hepatitis C serology reaction following IVIG administration.
Nixon
R R
RR
Department of Pathology, Oregon Health Sciences University, Portland 97201-3042.
Smith
S A
SA
Johnson
R L
RL
Pillers
D A
DA
D005189:False Positive Reactions; D005260:Female; D006526:Hepatitis C / Q000097:blood / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage*; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007275:Injections, Intravenous
D007136:Immunoglobulins