Effects of a microbial probiotic (Sporolactobacillus P 44) on postprandial porto-arterial concentration differences of glucose, galactose and amino-nitrogen in the growing pig.
Postprandial kinetics of porto-arterial concentration differences of glucose (G), galactose (Gal), L-lactic acid (LA), amino-nitrogen (AN) and urea (U) were studied in the pig after the ingestion of 10(7) colony-forming units (cfu) of Sporolactobacillus P 44 per g of feed. Eight fistulated pigs (portal vein and brachiocephalic trunk; mean body weight 70 +/- 4 kg) were used. The diet was based on skimmed milk (32%), barley (30%), maize (10%) and lactose (7%). The postprandial blood kinetics, 4 conducted per animal at 1-wk intervals, were studied during the 3 h following the ingestion of test meals of 1,000 g basal diet (BD) or the same diet supplemented by the bacteria (SD). The apparent absorption was estimated from the area between the portal and arterial concentrations. The areas of porto-arterial differences of G, Gal and AN of SD for the first 3 h after the meal were significantly higher after SD ingestion than those measured after BD intake. Plasma concentrations of U and porto-arterial differences of U and LA were not modified by the probiotic. These effects disappeared immediately after dietary supplement interruption, suggesting that added bacteria presence in the intestinal lumen was fundamental to the modifications observed in apparent absorption.
Rychen
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Centre de Recherche en Nutrition Animale, Société Chimique Roche, Saint-Louis, France.
Simões Nunes
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D000821:Animal Feed; D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D016122:Brachiocephalic Trunk; D004435:Eating; D005690:Galactose / Q000032:analysis*; D007408:Intestinal Absorption; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D007777:Lactobacillaceae; D008297:Male; D009584:Nitrogen / Q000097:blood*; D009919:Orchiectomy; D011169:Portal Vein; D013552:Swine / Q000254:growth & development / Q000378:metabolism*; D014508:Urea / Q000097:blood
D001786:Blood Glucose; D007773:Lactates; D019344:Lactic Acid; D014508:Urea; D009584:Nitrogen; D005690:Galactose