title: Tracheal intubation without neuromuscular block in children.
abstract: We have studied 80 healthy children, aged 2-14 yr, undergoing adenotonsillectomy in a double-blind, randomized design. Tracheal intubation facilitated by either suxamethonium 1.5 mg kg-1 or alfentanil 15 micrograms kg-1 was compared after induction of anaesthesia with propofol 3-4 mg kg-1. The quality of tracheal intubation was graded according to the ease of laryngoscopy, position of the vocal cords, coughing, jaw relaxation and movement of limbs. There were no significant differences in the overall assessment of intubating conditions between the two groups, and all children underwent successful tracheal intubation. Fewer patients coughed (P < 0.014) and limb movement was less common (P < 0.007) after tracheal intubation facilitated by suxamethonium. Alfentanil attenuated the haemodynamic responses to tracheal intubation.
authors.affiliation: Department of Anaesthesia, Aberdeen Royal Hospitals, Foresterhill.
authors.forename: M P
authors.initials: MP
authors.lastname: Steyn
authors.forename: A M
authors.initials: AM
authors.lastname: Quinn
authors.forename: J A
authors.initials: JA
authors.lastname: Gillespie
authors.forename: D C
authors.initials: DC
authors.lastname: Miller
authors.forename: C J
authors.initials: CJ
authors.lastname: Best
authors.forename: N S
authors.initials: NS
authors.lastname: Morton
mesh_terms: D000233:Adenoidectomy; D000293:Adolescent; D015760:Alfentanil; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D003371:Cough; D004311:Double-Blind Method; D005260:Female; D006339:Heart Rate; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D009068:Movement; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage; D009469:Neuromuscular Junction; D013390:Succinylcholine; D014068:Tonsillectomy
chemical_list: D009466:Neuromuscular Blocking Agents; D015760:Alfentanil; D013390:Succinylcholine