title: Expression of versican mRNA is developmentally regulated in the brain of the embryonic chick and the developing rat.
abstract: RNA prepared from the brains of chick embryos at 12 days of incubation contained a 12-kb transcript that hybridized with a cDNA probe for the aggregating proteoglycan versican. No transcripts were detected in the brains of newborn rats while, at 3 days of postnatal development, three sizes of transcripts were present. None were detected in the 6-day old brain and, at later stages, the smallest transcript predominated.
authors.affiliation: Department of Zoology, University of British Columbia, Vancouver, Canada.
authors.forename: T J
authors.initials: TJ
authors.lastname: Crawford
authors.forename: I G
authors.initials: IG
authors.lastname: Melhado
authors.forename: F R
authors.initials: FR
authors.lastname: Jirik
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development* / Q000378:metabolism; D001921:Brain / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D002642:Chick Embryo; D011508:Chondroitin Sulfate Proteoglycans / Q000235:genetics*; D037181:Lectins, C-Type; D051379:Mice; D012333:RNA, Messenger / Q000096:biosynthesis*; D051381:Rats; D053675:Versicans
chemical_list: D011508:Chondroitin Sulfate Proteoglycans; D037181:Lectins, C-Type; D012333:RNA, Messenger; C508323:Vcan protein, mouse; C508324:Vcan protein, rat; D053675:Versicans