title: Tc-99m DISIDA hepatobiliary scintigraphy in AIDS cholangitis.
abstract: Sixteen patients with documented AIDS cholangitis who underwent Tc-99m DISIDA hepatobiliary scintigraphy were retrospectively reviewed to assess the spectrum of changes observed in this disease. AIDS cholangitis was documented by either ERCP with aspiration/biopsy or the presence of typical sonographic/CT abnormalities with positive stool culture and a minimum of 6 months follow-up. Images were graded as regards parenchymal function (blood pool clearance, peak parenchymal activity, and degree of parenchymal retention), gallbladder visualization, presence of ductal dilatation, and time of intestinal activity. Three patterns were identified: 1) focal ductal dilatation with focal narrowing and focal or diffuse parenchymal retention; 2) ductal dilatation, without narrowing, and diffuse parenchymal retention; and 3) severe diffuse parenchymal retention with or without ductal abnormality. All 16 studies revealed abnormal parenchymal retention. Gallbladder nonvisualization was demonstrated in nine studies and delayed in two. The hepatobiliary scan is a very sensitive technique for evaluating AIDS cholangitis. Although a spectrum of findings may be observed, parenchymal retention with some degree of ductal abnormality is the most commonly observed pattern.
authors.affiliation: Department of Radiology, St. Vincent's Hospital & Medical Center of New York.
authors.forename: J C
authors.initials: JC
authors.lastname: Brunetti
authors.forename: R L
authors.initials: RL
authors.lastname: Van Heertum
authors.forename: J S
authors.initials: JS
authors.lastname: Kempf
authors.forename: A P
authors.initials: AP
authors.lastname: Yudd
authors.forename: J
authors.initials: J
authors.lastname: Farman
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000000981:diagnostic imaging* / Q000453:epidemiology; D000328:Adult; D001659:Biliary Tract / Q000000981:diagnostic imaging*; D002761:Cholangitis / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology; D003457:Cryptosporidiosis / Q000000981:diagnostic imaging*; D003586:Cytomegalovirus Infections / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007098:Imino Acids; D008099:Liver / Q000000981:diagnostic imaging*; D008297:Male; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D019785:Technetium Tc 99m Disofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019785:Technetium Tc 99m Disofenin