title: Case report--a neonate with nonimmune hydrops fetalis.
abstract: A post-dated intra-uterine growth retarded male Malay baby was born to a 30-year-old mother gravida II by Caesarean section. Her previous pregnancy ended in still-birth. The baby was severely asphyxiated at birth. He was intubated and immediately admitted to the neonatal intensive care unit. He had anasarca, anaemia, purpura and firm, massive hepatosplenomegaly. X-rays revealed ascites and bilateral metaphysiitis of the long bones. The haemoglobin level was 5.0 gm/dl and PCV 18.3%. Coombs' test was negative. Prothrombin time (PT) and partial thromboplastin time (PTT) were prolonged. The baby and mother were positive for Venereal Disease Research Laboratory (VDRL) and the treponema pallidum haemagglutination assay (TPHA) tests. The baby was actively resuscitated but expired at three and a half hours of life due to overwhelming sepsis associated with severe anaemia and disseminated intravascular coagulation.
authors.affiliation: Department of Paediatrics, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan.
authors.forename: S P
authors.initials: SP
authors.lastname: Ram
authors.forename: W A
authors.initials: WA
authors.lastname: Ariffin
authors.forename: Z
authors.initials: Z
authors.lastname: Kassim
mesh_terms: D000328:Adult; D001238:Asphyxia Neonatorum / Q000209:etiology; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D015160:Hydrops Fetalis / Q000209:etiology*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D013590:Syphilis, Congenital / Q000150:complications*