Papulonecrotic tuberculid secondary to disseminated Mycobacterium avium complex.
BACKGROUND
Papulonecrotic tuberculid is a rarely reported cutaneous reaction to the mycobacterium bacillus. It is most often encountered in association with tuberculosis. The clinical and histologic picture of the entity is a distinctive one, but the etiology of the disease process is uncertain. Therapy directed against the causative organism is dramatically successful.


METHODS
A 35-year-old white man with AIDS was referred to the Dermatology clinic for evaluation of a widespread skin eruption. The skin lesions were biopsied for histopathology and culture. From the cutaneous cultures Mycobacterium avium complex (MAC) organisms were grown.


RESULTS
We report the first case of papulonecrotic tuberculid manifestation in an AIDS patient with disseminated MAC. Unusual features seen in this case include the predominance of pruritic eschars rather than asymptomatic papules and the confirmation by special stains of mycobacterium organisms within the skin biopsy. Papulonecrotic tuberculid has not been previously associated with either MAC or AIDS.


CONCLUSIONS
Papulonecrotic tuberculid should be a diagnostic consideration in immunocompromised patients with MAC whose clinical and histologic features are compatible with this rare entity.
Williams
J T
JT
Department of Pathology, University of Texas Health Science Center, San Antonio 78284.
Pulitzer
D R
DR
DeVillez
R L
RL
D017088:AIDS-Related Opportunistic Infections / Q000473:pathology*; D000328:Adult; D006801:Humans; D008297:Male; D015270:Mycobacterium avium-intracellulare Infection / Q000473:pathology*; D012874:Skin Diseases, Infectious / Q000473:pathology*