title: Experimental experience with a temporary intraluminal heparin-bonded polyurethane arterial shunt.
abstract: After vascular injury, intraluminal arterial shunting may be employed if definitive surgery must be delayed. This paper describes use of a heparin-bonded polyurethane shunt to restore distal circulation after ligation of the femoral artery in sheep. In studies to determine tissue viability for 12 h after insertion into the femoral artery, five of seven shunts remained patent. In another series of experiments to study tissue viability after limb ischaemia, the femoral artery was ligated and a tight Esmarch bandage applied to the limb for 6 h before shunt insertion. The shunt remained patent for 12 h in five of six cases. Nearly all shunt failures occurred shortly after placement and were attributable to intimal damage arising from difficulties during insertion.
authors.affiliation: Medical Division, Chemical and Biological Defence Establishment, Porton Down, Salisbury, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Walker
authors.forename: S G
authors.initials: SG
authors.lastname: Mellor
authors.forename: G J
authors.initials: GJ
authors.lastname: Cooper
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D001783:Blood Flow Velocity; D001807:Blood Vessel Prosthesis; D001831:Body Temperature; D005121:Extremities / Q000098:blood supply* / Q000503:physiopathology; D005260:Female; D005263:Femoral Artery / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006493:Heparin / Q000008:administration & dosage; D011140:Polyurethanes; D012756:Sheep; D013997:Time Factors; D014654:Vascular Patency
chemical_list: D011140:Polyurethanes; D006493:Heparin