title: Lipid metabolism after liver transplantation from a living related donor.
abstract: 1. The recovery of lipid metabolism was investigated in paediatric patients treated for terminal liver disease by liver transplantation from living related donors. 2. The cholesterol ester ratio (esterified cholesterol/total cholesterol) and the total cholesterol/phospholipid ratio increased from preoperative values of 0.35 +/- 0.04 and 0.59 +/- 0.03 to 0.65 +/- 0.01 and 0.68 +/- 0.01 at 3 weeks after liver transplantation in successful cases (means +/- SEM, n = 26), respectively, whereas these two parameters decreased in failed cases (n = 4). 3. Biochemical analysis indicated that weekly recoveries in the cholesterol ester ratio and the total cholesterol/phospholipid ratio are characteristic of successful liver transplantation with a graft from a living related donor.
authors.affiliation: Second Department of Surgery, Faculty of Medicine, Kyoto University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sano
authors.forename: A
authors.initials: A
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Uemoto
authors.forename: K
authors.initials: K
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Ozawa
mesh_terms: D000293:Adolescent; D016632:Apolipoprotein A-I / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D007223:Infant; D008055:Lipids / Q000097:blood*; D016031:Liver Transplantation; D008297:Male; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood; D014019:Tissue Donors
chemical_list: D016632:Apolipoprotein A-I; D008055:Lipids; D002784:Cholesterol; D007862:Phosphatidylcholine-Sterol O-Acyltransferase