title: Free flap reconstruction of tumors involving the cranial base.
abstract: The authors describe their experience in treating 24 patients who underwent resection of tumors involving anterior, middle or posterior cranial fossa with immediate reconstruction. All were reconstructed with free flaps, 15 rectus abdominis, 4 radial forearm, 3 latissimus dorsi, 2 great omentum, and one scapular flap. There was one latissimus dorsi flap loss due to arterial thrombosis in a heavily irradiated patient. Three patients presented with a temporary cerebrospinal fluid leak, one of them with meningitis which resolved after intravenous antibiotics and continuous lumbar drainage. Fifteen patients were followed (mean 2 years). Five died of recurrence. Four presented local recurrence. Six patients are alive with no signs of recurrence. Free flaps, especially the rectus abdominis flap and the latissimus dorsi, are versatile flaps and may be easily positioned to cover several structures or anatomical surfaces.
authors.affiliation: Division of Plastic Surgery, Faculty of Medicine, University of São Paulo (FMUSP), Brazil.
authors.forename: J M
authors.initials: JM
authors.lastname: Besteiro
authors.forename: F E
authors.initials: FE
authors.lastname: Aki
authors.forename: M C
authors.initials: MC
authors.lastname: Ferreira
authors.forename: L R
authors.initials: LR
authors.lastname: Medina
authors.forename: C
authors.initials: C
authors.lastname: Cernea
mesh_terms: D000328:Adult; D000368:Aged; D003388:Cranial Fossa, Posterior; D005260:Female; D006801:Humans; D008722:Methods; D008866:Microsurgery; D008875:Middle Aged; D011183:Postoperative Complications; D012888:Skull Neoplasms / Q000601:surgery*; D013524:Surgical Flaps