Initial rapid decrease in visual acuity in siblings with Stargardt's disease.
Two siblings with Stargardt's disease who had an initial rapid decrease in visual acuity were reported. The 8-year-old boy and his 5-year-old sister experienced a bilateral visual decrease within a period of 3 months. Their parents had a consanguineous relationship. Macular changes and blocked choroidal fluorescence were noted bilaterally in both children. Normal color vision, normal or subnormal electroretinographic findings, and subnormal electro-oculographic responses were found. Stargardt's disease should be included in the list of conditions showing rapid decrease in visual acuity.
Hayasaka
S
S
Department of Ophthalmology, Shimane Medical University, Japan.
Kurome
H
H
Noda
S
S
Mihara
M
M
D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008268:Macular Degeneration / Q000235:genetics* / Q000503:physiopathology*; D008297:Male; D010375:Pedigree; D014786:Vision Disorders / Q000503:physiopathology*; D014792:Visual Acuity