Pulmonary hypertension associated with non-cirrhotic portal hypertension in systemic lupus erythematosus.
A case of non-cirrhotic portal hypertension in a patient with systemic lupus erythematosus, the first of our knowledge, is described. Severe pulmonary hypertension was associated with the portal hypertension and with markers of active auto-immunity. Pulmonary hypertension has not previously been associated with non-cirrhotic portal hypertension. The coexistence of vasculopathy of the portal and pulmonary vascular beds in this patient with active autoimmunity supports the postulate that portal-pulmonary hypertension may be immunologically mediated.
Woolf
D
D
Rheumatic Diseases Unit, University of Cape Town, Observatory, South Africa.
Voigt
M D
MD
Jaskiewicz
K
K
Kalla
A A
AA
D000328:Adult; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications* / Q000473:pathology; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000473:pathology