Germ cell tumors of the ovary arising after dermoid cyst resection: a long-term follow-up study.
OBJECTIVE
To study the long-term ovarian neoplastic consequences of resection of a dermoid cyst.


METHODS
The study population comprised 99 patients who were operated on for an ovarian dermoid cyst. Follow-up information was obtained for 91 women for a mean period of 5.06 +/- 2.46 years.


RESULTS
Of the 99 women, 18 had bilateral dermoid cysts. Multiple dermoid cysts in a single ovary were found in nine of the women with bilateral cysts and in one of the remaining patients. Two patients developed malignant germ cell tumors, and three developed a recurrent dermoid cyst in an ovary from which a dermoid cyst had previously been extracted. Bilateral or multiple ovarian dermoid cysts were present at the initial operation in four (80%) of these patients.


CONCLUSIONS
Women with bilateral or multiple dermoid cysts may include a subgroup of patients with a greater tendency to develop future ovarian germ cell neoplasms.
Anteby
E Y
EY
Department of Obstetrics and Gynecology, Hadassa University Hospital, Mt. Scopus, Jerusalem, Israel.
Ron
M
M
Revel
A
A
Shimonovitz
S
S
Ariel
I
I
Hurwitz
A
A
D000328:Adult; D003884:Dermoid Cyst / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D018237:Germinoma / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery*; D013997:Time Factors