Delayed and severe toxicities of a herbicide containing glufosinate and a surfactant.
We report a case of a 59-y-old woman who ingested a herbicide containing glufosinate. Though suffering from severe toxicity of this herbicide, she did not develop convulsions, which experimentally occurs in rats treated with glufosinate. The mechanisms of convulsions are not clear. Several clinical findings in poisoning by this herbicide are suspected to be caused by the surfactant components.
Koyama
K
K
Department of Emergency Medicine, Hidaka Hospital, Gumma, Japan.
Andou
Y
Y
Saruki
K
K
Matsuo
H
H
D000613:Aminobutyrates / Q000506:poisoning*; D002606:Charcoal / Q000627:therapeutic use; D003244:Consciousness Disorders / Q000139:chemically induced / Q000523:psychology; D004231:Diuresis; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006540:Herbicides / Q000506:poisoning*; D006801:Humans; D007564:Japan; D008875:Middle Aged; D011041:Poisoning / Q000188:drug therapy; D012640:Seizures / Q000139:chemically induced; D013406:Suicide, Attempted; D013501:Surface-Active Agents / Q000506:poisoning*
D000613:Aminobutyrates; D006540:Herbicides; D013501:Surface-Active Agents; D002606:Charcoal; C003121:phosphinothricin; D005665:Furosemide