title: [Reproducibility of symptom-limited oxygen consumption and anaerobic threshold within the scope of spiroergometric studies in patients with heart failure].
abstract: A prerequisite for the clinical utility of cardiopulmonary exercise testing is high reproducibility of gas-exchange characteristics. Therefore, we studied reproducibility of peak oxygen uptake and anaerobic threshold during bicycle-exercise stress testing in 34 patients with congestive heart failure in NYHA classes II and III. Additionally, we analyzed interobserver variability with regard to anaerobic threshold measured with the V-slope method. Correlations of results between two exercise stress tests were high concerning peak oxygen uptake and anaerobic threshold (r = 0.871 and r = 0.917, respectively). For both measures, however, 90% percentile of the relative difference between tests was 25% and 22%, respectively. Correlation between two observers with regard to the anaerobic threshold was high (r = 0.985). We conclude that reproducible determination of peak oxygen uptake and anaerobic threshold is possible in heart-failure patients. In individual subjects, however, considerable variation of results may occur during serial exercise testing. Interobserver variability with regard to anaerobic threshold is low.
authors.affiliation: Abteilung für Innere Medizin mit Schwerpunkt Kardiologie und Pulmologie, Klinikum Steglitz, Freie Universität Berlin.
authors.forename: S
authors.initials: S
authors.lastname: Behrens
authors.forename: D
authors.initials: D
authors.lastname: Andresen
authors.forename: T
authors.initials: T
authors.lastname: Brüggemann
authors.forename: C
authors.initials: C
authors.lastname: Ehlers
authors.forename: R
authors.initials: R
authors.lastname: Schröder
mesh_terms: D000328:Adult; D000368:Aged; D015308:Anaerobic Threshold / Q000502:physiology*; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology; D003327:Coronary Disease / Q000503:physiopathology; D005080:Exercise Test; D005260:Female; D006333:Heart Failure / Q000503:physiopathology*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology; D010100:Oxygen / Q000097:blood*; D015203:Reproducibility of Results; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D010100:Oxygen
vernacular_title: Reproduzierbarkeit der symptomlimitierten Sauerstoffaufnahme und der anaeroben Schwelle im Rahmen spiroergometrischer Untersuchungen bei Patienten mit Herzinsuffizienz.