Adult rhabdomyoma. A light microscopic, ultrastructural, virologic, and immunologic analysis.
Adult rhabdomyoma is a rare benign tumor of skeletal muscle origin that frequently arises from musculature of the head and neck region. In this study we report five cases of adult rhabdomyoma. Light and electron microscopic examination revealed the typical cellular features as described by others. The results of immunophenotyping and quantitation of nucleolar organizer regions were consistent for a benign skeletal muscle tumor. Epstein-Barr virus and human papillomavirus genomic DNA could not be detected by in situ hybridization.
Cleveland
D B
DB
Temple University School of Medicine, Department of Pathology, Philadelphia, PA 19140.
Chen
S Y
SY
Allen
C M
CM
Ahing
S I
SI
Svirsky
J A
JA
D000199:Actins / Q000032:analysis; D000368:Aged; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal; D004279:DNA, Viral / Q000032:analysis; D003893:Desmin / Q000032:analysis; D005260:Female; D006258:Head and Neck Neoplasms / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D016130:Immunophenotyping; D017403:In Situ Hybridization; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor / Q000473:pathology*; D009062:Mouth Neoplasms / Q000276:immunology / Q000382:microbiology / Q000473:pathology*; D009211:Myoglobin / Q000032:analysis; D009697:Nucleolus Organizer Region / Q000473:pathology; D027383:Papillomaviridae / Q000302:isolation & purification; D012207:Rhabdomyoma / Q000276:immunology / Q000382:microbiology / Q000473:pathology*; D016622:Silver Staining
D000199:Actins; D000911:Antibodies, Monoclonal; D004279:DNA, Viral; D003893:Desmin; D009211:Myoglobin