Search for the genes of human essential hypertension.
Hypertension shares several characteristics with diabetes, atherosclerosis and asthma. These common diseases are caused by environmental factors and predisposing genes and they represent a major cost in developed countries. Use of molecular techniques: Much information is expected from the identification of the molecular bases of these diseases, and from the molecular characterization of the predisposing variants and their effects on the clinical manifestations of these pathologies. Hypertension is now a target for genetic studies, and some interesting results have been obtained in humans and in animal models.
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INSERM U 36, Collège de France, Paris.
D000808:Angiotensinogen / Q000235:genetics; D000818:Animals; D003001:Cloning, Molecular; D004195:Disease Models, Animal; D005260:Female; D005819:Genetic Markers; D014644:Genetic Variation; D006801:Humans; D006973:Hypertension / Q000235:genetics*; D008297:Male; D008967:Molecular Biology; D051381:Rats; D012307:Risk Factors
D005819:Genetic Markers; D000808:Angiotensinogen