A case of transient hyperphosphatasaemia following vitamin D-deficient rickets.
A seven-month-old boy with a diagnosis of vitamin-D deficiency rickets is presented. After treatment with vitamin-D, biochemical and radiological improvement was noted. At 14-months of age the plasma akaline phosphatase activity valve was found to be elevated even though rickets was not present. A diagnosis of hyperphosphatasemia was established. Although rare in infancy, transient hyperphospha tasemia may occur following vitamin-D deficient rickets. This possibility should be considered when evaluating laboratory results in such cases.
Kutilek
S
S
Department of Pediatrics, Charles University, 1st Faculty of Medicine, Prague, Czechoslovakia.
Stĕpan
J
J
Bayer
M
M
D000469:Alkaline Phosphatase / Q000097:blood; D006801:Humans; D007223:Infant; D008297:Male; D010760:Phosphorus Metabolism Disorders / Q000201:enzymology / Q000209:etiology*; D012279:Rickets / Q000150:complications*; D014808:Vitamin D Deficiency / Q000150:complications*
D000469:Alkaline Phosphatase