Effect of ethanol on Escherichia coli cells. Enhancement of DNA synthesis due to ethanol treatment.
Increased ethanol concentration in the nutrient medium gradually slowed down the growth of Escherichia coli cells. However, during growth in the presence of 5% ethanol, DNA synthesis per cell increased about 2.5-fold compared to control cells. There was a 40-45% increase in plasmid copy number in the ethanol-treated cells.
Basu
T
T
Department of Biophysics, Molecular Biology and Genetics, University College of Science, Calcutta, India.
Poddar
R K
RK
D002462:Cell Membrane / Q000187:drug effects; D004261:DNA Replication / Q000187:drug effects*; D004269:DNA, Bacterial / Q000096:biosynthesis*; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D000431:Ethanol / Q000494:pharmacology*; D008563:Membrane Lipids / Q000378:metabolism; D010957:Plasmids / Q000187:drug effects; D013268:Stimulation, Chemical
D004269:DNA, Bacterial; D008563:Membrane Lipids; D000431:Ethanol