title: Spinal tumour due to primary hyperparathyroidism causing sciatica: case report.
abstract: We report a unilateral intraspinal cyst-like lesion adjacent to the lamina and facet joint at the L4-L5 level producing sciatica. Histological examination revealed multinucleate giant cells suggesting a brown tumour. Further studies disclosed primary hyperparathyroidism, whose first manifestation was the lumbar nerve root compression. Previous cases of compression of neural structures by spinal brown tumours are reviewed and a radiological differential diagnosis is presented.
authors.affiliation: Department of Radiology, Hôpital Cantonal Universitaire, Geneva, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Motateanu
authors.forename: J P
authors.initials: JP
authors.lastname: Déruaz
authors.forename: H
authors.initials: H
authors.lastname: Fankhauser
mesh_terms: D001859:Bone Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000209:etiology; D012585:Sciatica / Q000209:etiology*; D013126:Spinal Nerve Roots / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed