title: Repeated large-dose haptoglobin therapy in an extensively burned patient: case report.
abstract: The case of a 24-year-old man who sustained a 100% body surface area burn and inhalation injury is presented. Hemoglobinuria reappeared 2 hours after haptoglobin was first administered. In addition to individualized fluid resuscitation and plasma administration, a large dose of haptoglobin was repeatedly administered while we monitored for occult blood in the centrifuged urine. As a result, postburn shock and acute renal failure were prevented.
authors.affiliation: Department of Traumatology and Critical Care Medicine, Sapporo Medical University, School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Imaizumi
authors.forename: K
authors.initials: K
authors.lastname: Tsunoda
authors.forename: N
authors.initials: N
authors.lastname: Ichimiya
authors.forename: T
authors.initials: T
authors.lastname: Okamoto
authors.forename: A
authors.initials: A
authors.lastname: Namiki
mesh_terms: D058186:Acute Kidney Injury / Q000503:physiopathology / Q000517:prevention & control*; D000328:Adult; D002056:Burns / Q000150:complications / Q000628:therapy*; D002059:Burns, Inhalation / Q000628:therapy; D006242:Haptoglobins / Q000627:therapeutic use*; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D012151:Resuscitation; D012774:Shock, Traumatic / Q000517:prevention & control*
chemical_list: D006242:Haptoglobins