The influence of UV irradiation on vitamin D metabolism in children with chronic renal diseases.
The aim of this study was to find out whether an improvement of vitamin D metabolism and its metabolites and a decrease of parathormones can be reached through a diet and UV irradiation. Forty-eight children with kidney insufficiency were divided into four groups: Group 1--diet according to Bergström with EAA and cetoanalogue supplementation plus UV therapy; Group 2--diet plus EAA and cetoanalogue supplementation without UV therapy; Group 3--without diet and supplementation of EAA and ceto but with UV therapy; Group 4--without any diet and without UV therapy. The average levels of kidney insufficiency in all children at the stage of a manifest kidney insufficiency were not significantly different. As a result it became obvious that children exposed to UV irradiation with or without a diet had better post-treatment values and that children with kidney insufficiency reacted to UV therapy plus diet best of all. One can obtain the same results also by oral vitamin D therapy, although we have to point out the danger of calcinosis and stone formation which the author could frequently demonstrate, but never after UV treatment.
Lemke
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Rehabilitation Clinic of Children with Chronic Diseases, Allgemeine Hospitalgesellschaft, Kartzow, Germany.
D000601:Amino Acids, Essential / Q000008:administration & dosage*; D002648:Child; D003131:Combined Modality Therapy; D003404:Creatinine / Q000097:blood; D004044:Dietary Proteins / Q000008:administration & dosage*; D004100:Dihydroxycholecalciferols / Q000097:blood; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000178:diet therapy* / Q000532:radiotherapy*; D010281:Parathyroid Hormone / Q000097:blood; D014467:Ultraviolet Therapy; D014807:Vitamin D / Q000097:blood* / Q000528:radiation effects*
D000601:Amino Acids, Essential; D004044:Dietary Proteins; D004100:Dihydroxycholecalciferols; D010281:Parathyroid Hormone; D014807:Vitamin D; D003404:Creatinine