title: Bioresorbable screws for facial bone reconstruction: a pilot study in rabbits.
abstract: Rigid fixation using plates and screws is an accepted mode of repair for facial fractures and osteotomies. To avoid potential complications associated with metal implants, bioresorbable implants are being developed. A study was performed to assess the strength over time of three bioresorbable polymeric screws for facial bone reconstruction. Screws of each polymer type and a titanium control were implanted in the periorbital bones of eight rabbits. Rabbits were euthanized at various time intervals. Pull-out testing and histological analysis were performed. Results showed varying degrees of resorption and screw pull-out strength dependent on time and polymer type, and no change in the control. This study demonstrates that bioresorbable screws can be used in bone, although the optimal choices for human implantation are yet to be determined.
authors.affiliation: Department of Otolaryngology, SUNY Health Science Center, Syracuse 13210.
authors.forename: R M
authors.initials: RM
authors.lastname: Kellman
authors.forename: S C
authors.initials: SC
authors.lastname: Huckins
authors.forename: J
authors.initials: J
authors.lastname: King
authors.forename: D
authors.initials: D
authors.lastname: Humphrey
authors.forename: L
authors.initials: L
authors.lastname: Marentette
authors.forename: D C
authors.initials: DC
authors.lastname: Osborn
mesh_terms: D000818:Animals; D001673:Biodegradation, Environmental; D001863:Bone Screws; D005147:Facial Bones / Q000473:pathology / Q000601:surgery*; D008297:Male; D008422:Materials Testing; D008954:Models, Biological; D009915:Orbit / Q000473:pathology / Q000601:surgery; D010865:Pilot Projects; D011108:Polymers; D019736:Prostheses and Implants; D011817:Rabbits; D014025:Titanium
chemical_list: D011108:Polymers; C046409:polyglyconate; D014025:Titanium