Human papillomavirus gene sequences in washed human sperm deoxyribonucleic acid.
The present study demonstrated the presence of HPV gene sequences in Percoll-washed sperm cells using polymerase chain reaction primers targeting smaller gene regions. Up to 64% of the sperm specimens were shown to contain gene sequences indicative of the presence of HPV. Human papillomavirus type 16 was detected about twice as often as HPV type 18. The results suggest the possible role of sperm as a vector for HPV.
Chan
P J
PJ
Department of Gynecology and Obstetrics, Loma Linda University School of Medicine, California 92350.
Su
B C
BC
Kalugdan
T
T
Seraj
I M
IM
Tredway
D R
DR
King
A
A
D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics; D005814:Genes, Viral; D006801:Humans; D008297:Male; D027383:Papillomaviridae / Q000235:genetics*; D030361:Papillomavirus Infections / Q000635:transmission; D016133:Polymerase Chain Reaction; D013094:Spermatozoa / Q000737:chemistry*; D014412:Tumor Virus Infections / Q000635:transmission
D004279:DNA, Viral