Basaloid carcinomas of salivary glands.
Three cases of carcinoma of major salivary glands with basaloid morphology are presented. One case was a clear example of a basal cell adenocarcinoma, an uncommon and infrequently recognized. low-grade tumour of major salivary glands. The remaining two cases showed a higher cytological grade of malignancy but shared some features of basal cell adenocarcinoma. Common features included the architectural pattern and myoepithelial cell differentiation, as demonstrated by smooth muscle-specific actin positivity, in cells associated with the deposition of extracellular basal lamina-like material. The relationship between these cases and adenoid cystic carcinoma is discussed.
Gallimore
A P
AP
Department of Histopathology, University College London Hospitals, UK.
Spraggs
P D
PD
Allen
J P
JP
Hobsley
M
M
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D012468:Salivary Gland Neoplasms / Q000473:pathology*