title: [Studies on metal allergy in the field of dentistry--treatment with application of X-ray fluorescence spectroscope analysis in detection of allergen metals].
abstract: The most effective method to treat metal allergy may be allergen elimination. Information on the exact location of the allergens becomes essential for this treatment. An XRFS (X-ray fluorescence spectroscope) was used for the detection of such elements and applied for the treatment of these patients. 1. Evaluation of the apparatus preceding its clinical application proved that the reliability and the detection limit for pure elements were comparative to those of the Electron Probe Microanalyzer. A notable decrease in the emitted X-ray intensity was observed when a sample was analyzed through a medium with thickness of more than 5 mm. 2. The analysis results of the restorations showed that the most frequently used alloys were Ag-Sn-Hg amalgams, Au-Ag-Pd alloys and Ag alloys. Some of the elements with high prevalence rates were Ag, Cu, Zn, Au, Pd, Sn, and Hg. 3. Personal and household items suspected of containing allergen metals were analyzed. Some of the frequently detected elements were Fe, Cu, Mn, Zn, Ni, Cr, and Au. 4. With XRFS, analysis of bulk metals and those samples in various forms became possible. A clinical case with the lesion resolved after the allergen elimination was reported. This proved that the use of XRFS enabled us to deal more definitely and effectively towards metal allergy.
authors.affiliation: Department of Prosthodontics II, Faculty of Dentistry, Tokyo Medical and Dental University.
authors.forename: N
authors.initials: N
authors.lastname: Suzuki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000485:Allergens / Q000032:analysis*; D002648:Child; D017266:Dental Prosthesis / Q000009:adverse effects; D004577:Electron Probe Microanalysis; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology* / Q000628:therapy; D007223:Infant; D008297:Male; D008670:Metals / Q000009:adverse effects*; D008875:Middle Aged; D013052:Spectrometry, X-Ray Emission
chemical_list: D000485:Allergens; D008670:Metals