Antiemetic-induced akathisia in cancer patients receiving chemotherapy.
A structured, prospective telephone interview was used to assess the prevalence of akathisia in 24 cancer patients receiving metoclopramide or prochlorperazine during or after chemotherapy. Half of the patients reported subjective motor restlessness, and 75% stated that they would not have informed staff. This report suggests that akathisia is frequently unrecognized in chemotherapy patients receiving metoclopramide and prochlorperazine.
Fleishman
S B
SB
Department of Medicine and Psychiatry, Long Island Jewish Medical Center, New Hyde Park, NY 11042.
Lavin
M R
MR
Sattler
M
M
Szarka
H
H
D017109:Akathisia, Drug-Induced / Q000453:epidemiology* / Q000209:etiology; D000970:Antineoplastic Agents / Q000009:adverse effects; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced / Q000517:prevention & control; D009369:Neoplasms / Q000188:drug therapy*; D011346:Prochlorperazine / Q000009:adverse effects* / Q000627:therapeutic use; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D013689:Telephone; D014839:Vomiting / Q000139:chemically induced / Q000517:prevention & control
D000970:Antineoplastic Agents; D008787:Metoclopramide; D011346:Prochlorperazine