title: Six-year follow-up of multiple joint replacement surgery to the lower limbs.
abstract: We report a 6-yr follow-up study of an original population of 50 patients who had three or more major joints (hips and knees) replaced. Thirty-one of 32 surviving patients were still ambulant in the community, and all patients described significant pain relief. No RA patient was requiring permanent inpatient or residential care and the family remained the main social support. They remained a very disabled group with a median Health Assessment Questionnaire score of 2.75. Ten required revision surgery: three hips and seven knees; four patients required their fourth lower limb joint (hip/knee) replaced and seven patients required surgery to the upper limbs and nine feet during the follow-up period. The median 10-yr survival of hip and knee arthroplasties in multiple joint replacement (MJR) patients with RA was 90.5 and 78.6% respectively. There was an increased incidence of cervical myelopathy in MJR patients 16.9%. The mortality rate was higher than expected (standardized mortality ratio = 590) but the actual surgery was not implicated. MJR therefore appears to be a worthwhile policy, even at long-term follow-up.
authors.affiliation: Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne.
authors.forename: J E
authors.initials: JE
authors.lastname: McDonagh
authors.forename: J
authors.initials: J
authors.lastname: Ledingham
authors.forename: C M
authors.initials: CM
authors.lastname: Deighton
authors.forename: I D
authors.initials: ID
authors.lastname: Griffiths
authors.forename: I M
authors.initials: IM
authors.lastname: Pinder
authors.forename: D J
authors.initials: DJ
authors.lastname: Walker
mesh_terms: D001172:Arthritis, Rheumatoid / Q000453:epidemiology / Q000601:surgery; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D007720:Knee Prosthesis; D007866:Leg / Q000601:surgery*; D008485:Medical Audit; D010003:Osteoarthritis / Q000453:epidemiology / Q000601:surgery; D017063:Outcome Assessment, Health Care; D011795:Surveys and Questionnaires