Serum inhibits penicillin-induced L-form growth in Staphylococcus aureus: a note of caution on the use of serum in cultivation of bacterial L-forms.
Heat-inactivated horse serum inhibited penicillin-induced L-form colony formation in Staphylococcus aureus when included in an osmotically stabilized culture medium. Most, perhaps all, L-form colonies that appeared with low frequencies on the serum-supplemented medium were of the penicillin-independent, stable type. This relationship must be taken into account when use of serum is considered for L-form cultivation.
Shimokawa
O
O
Department of Microbiology, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
Ikeda
M
M
Umeda
A
A
Nakayama
H
H
D001769:Blood; D015169:Colony Count, Microbial; D003470:Culture Media; D007740:L Forms / Q000254:growth & development* / Q000648:ultrastructure; D010406:Penicillins / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development*
D003470:Culture Media; D010406:Penicillins