title: Chronic interstitial cystitis occurring during the shift between rheumatoid arthritis and lupus.
abstract: This case reports documents the progressive development of chronic interstitial cystitis during the overlapping process from rheumatoid arthritis to lupus. Concomitantly high titer antinuclear antibody with an anti-68 KD RNP pattern and other biological markers of lupus were observed in the blood. The symptoms dramatically improved under methotrexate therapy. The pathogenic mechanism is discussed.
authors.affiliation: Division of Rheumatology, Erasmus University Hospital, University of Brussels.
authors.forename: M A
authors.initials: MA
authors.lastname: Golstein
authors.forename: M
authors.initials: M
authors.lastname: Manto
authors.forename: J C
authors.initials: JC
authors.lastname: Noel
authors.forename: T
authors.initials: T
authors.lastname: Appelboom
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications*; D001327:Autoimmune Diseases / Q000503:physiopathology; D002908:Chronic Disease; D003556:Cystitis / Q000188:drug therapy / Q000209:etiology / Q000276:immunology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000209:etiology*; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged
chemical_list: D008727:Methotrexate