title: Acute left colonic diverticulitis: a prospective analysis of 226 consecutive cases.
abstract: BACKGROUND
  The purpose of this prospective study was to evaluate the immediate and late outcome of acute left colonic diverticulitis and to correlate it with age (younger and older than 50 years of age), gender, and initial computed tomography (CT) findings.
  
  
  METHODS
  Analysis was made of data collected prospectively from all patients admitted because of acute colonic diverticulitis between October 1986 and January 1992. Diagnosis relied on results of operation, CT, and Gastrografin enema. Two hundred twenty-six patients were urgently hospitalized for acute left colonic diverticulitis; 47 were younger than 50 years of age (21%).
  
  
  RESULTS
  Sixty-six patients (29%) were operated on during their first hospitalization. The remaining 160 patients treated conservatively underwent CT and an enema within 72 hours of admission. Fifty-nine of 179 patients (33%) older than 50 years of age required operation during their first attack, compared with 7 in 47 patients (15%) younger than 50 years of age (p = 0.02), although on CT severe diverticulitis was found in 36 of 141 patients (26%) older than 50 years of age and in 16 of 43 patients (37%) younger than 50 years of age (p = 0.13). Of the 160 patients treated conservatively, 11 of 40 patients (28%) younger than 50 years of age experienced recurrences or complications after their first discharge, compared with 16 in 120 patients (13%) older than 50 years of age (p = 0.04).
  
  
  CONCLUSIONS
  Patients younger than 50 years of age were significantly more prone to recurrences and complications after conservative treatment of their diverticulitis, whereas older patients required operation significantly more often during their first hospitalization.
authors.affiliation: Department of Digestive Surgery, University Hospital, Geneva, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Ambrosetti
authors.forename: J H
authors.initials: JH
authors.lastname: Robert
authors.forename: J A
authors.initials: JA
authors.lastname: Witzig
authors.forename: D
authors.initials: D
authors.lastname: Mirescu
authors.forename: P
authors.initials: P
authors.lastname: Mathey
authors.forename: F
authors.initials: F
authors.lastname: Borst
authors.forename: A
authors.initials: A
authors.lastname: Rohner
mesh_terms: D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D004239:Diverticulitis, Colonic / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed