Haptoglobin subtypes among four different populations.
Haptoglobin subtypes were analysed by isoelectric focusing in four populations from Colombia, England, Nigeria, and India. There is a wide range of variation of allele frequencies in these four populations: HP*1S = 15-28%, HP*1F = 5-19%, HP*2FS = 54-79%. With the exception of the English, and the Spanish-speaking population of Colombia, all interpopulation comparisons showed significant heterogeneity. There is an extreme variation for the HP*1F allele in different populations, and a possible geographical cline of the HP*2FS allele increasing from west to east. The data presented here suggest that HP subtypes provide a useful anthropogenetic marker for racial differentiation.
Mastana
S S
SS
Department of Human Sciences, Loughborough University of Technology, UK.
Bernal
J E
JE
Onyemelukwe
G C
GC
Papiha
S S
SS
D000483:Alleles; D002874:Chromosome Mapping; D004739:England; D005819:Genetic Markers; D006242:Haptoglobins / Q000235:genetics*; D006630:Hispanic or Latino; D006801:Humans; D007194:India; D009549:Nigeria; D011110:Polymorphism, Genetic
D005819:Genetic Markers; D006242:Haptoglobins