Familial occurrence of subependymoma. Report of two cases.
Subependymomas are unusual tumors believed to arise from the bipotential subependymal cell. Previous reports of familial occurrence of subependymoma have involved monozygous twins and siblings. The authors describe the first reported occurrence of fourth ventricular subependymoma in a father and son, suggesting the possibility of direct inheritance.
Ryken
T C
TC
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City.
Robinson
R A
RA
VanGilder
J C
JC
D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis / Q000235:genetics*; D005192:Family Health; D018315:Glioma, Subependymal / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged