Complete resolution of breast cancer bone metastasis through the use of beta-interferon and tamoxifen.
A case report is described referring to a patient affected by single bone metastasis to the cranium from breast cancer. A traditional pharmacological approach was tried but proved clinically disappointing, though radiological and scintigraphic investigation confirmed a complete regression of the metastasis following a combined therapy with beta-interferon and tamoxifen for six months. Results suggest that beta-interferon and tamoxifen may offer an alternative effective approach in treating metastatic breast cancer.
Campisi
C
C
Instituto di Tecnologie Biomediche del CNR, Roma.
Terenzi
S
S
Bandierini
A
A
Ferrone
L
L
Mozzicafreddo
A
A
Raffaele
M
M
Zappala
A
A
Tomao
S
S
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D016899:Interferon-beta / Q000008:administration & dosage*; D013629:Tamoxifen / Q000008:administration & dosage*
D013629:Tamoxifen; D016899:Interferon-beta