Dermatomyositis occurring during psoralen A (PUVA) therapy.
Dermatomyositis (DM) developed in a 35-year-old woman after 2 months of psoralen ultraviolet-A (PUVA) therapy for presumed psoriasis. Her disease was characterized by symmetrical proximal muscle weakness and cutaneous lesions compatible with DM. In addition, laboratory abnormalities included a positive antinuclear antibody, and elevated levels of creatine kinase and aldolase. This is the first report of DM developing during PUVA therapy.
Sinoway
P A
PA
University of Louisville, Department of Medicine, KY.
Davidson
C L
CL
Callen
J P
JP
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D015551:Autoimmunity; D003882:Dermatomyositis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D011701:PUVA Therapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy / Q000473:pathology; D013997:Time Factors
D000974:Antibodies, Antinuclear