title: Assessment of praziquantel therapy in treatment of Schistosoma mansoni infection.
abstract: The present study is the first report of the epidemiological survey carried out as a part of the Praziquantel resistance project which is one of the projects of Schistosomiasis Research Project (SRP) in Egypt. The results of the study, which has been carried out in 3 villages, revealed that praziquantel is effective as an antischistosomal drugs and reduced egg count significantly. However at the end of the study some cases remained infected in spite of the three treatment regimens. Several factors can be responsible, among them is the presence of resistance strains, which will only be elucidated in the subsequent steps of the project, when identification of resistant strains in experimental animals will be carried out.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Zagazig University, Egypt.
authors.forename: M
authors.initials: M
authors.lastname: Ismail
authors.forename: M
authors.initials: M
authors.lastname: Attia
authors.forename: A A
authors.initials: AA
authors.lastname: Metweally
authors.forename: A M
authors.initials: AM
authors.lastname: Farghaly
authors.forename: J
authors.initials: J
authors.lastname: Bruce
authors.forename: J
authors.initials: J
authors.lastname: Bennett
authors.forename: A A
authors.initials: AA
authors.lastname: el-Badawy
authors.forename: M H
authors.initials: MH
authors.lastname: Hussein
mesh_terms: D004351:Drug Resistance; D004534:Egypt / Q000453:epidemiology; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D010270:Parasite Egg Count; D011223:Praziquantel / Q000627:therapeutic use*; D015995:Prevalence; D012555:Schistosomiasis mansoni / Q000188:drug therapy* / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D011223:Praziquantel