title: Pigmented ameloblastic fibro-odontoma with melanophages.
abstract: A case of pigmented ameloblastic fibro-odontoma in the mandible of a 9-year-old Japanese girl is reported. In this tumor, melanin was widely distributed in the nests of the odontogenic epithelial component, and an aggregation of large round melanophages with a large amount of melanin similar to nevus cells was observed in the areas of the connective tissue component. A considerable number of dendritic cells that were considered to be melanocytes were scattered in the epithelial nests. This is the first case of pigmented odontogenic tumor that showed such extensive pigmentation with an aggregation of melanophages.
authors.affiliation: Department of Oral Pathology, Kagoshima University Dental School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kitano
authors.forename: S
authors.initials: S
authors.lastname: Tsuda-Yamada
authors.forename: I
authors.initials: I
authors.lastname: Semba
authors.forename: T
authors.initials: T
authors.lastname: Mimura
authors.forename: E
authors.initials: E
authors.lastname: Nozoe
authors.forename: M
authors.initials: M
authors.lastname: Setoyama
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D008264:Macrophages; D008339:Mandibular Neoplasms / Q000737:chemistry / Q000473:pathology*; D008543:Melanins / Q000032:analysis; D008544:Melanocytes; D009810:Odontoma / Q000737:chemistry / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis
chemical_list: D008543:Melanins; D009418:S100 Proteins