Leptomeningeal gliomatosis.
The diagnosis of leptomeningeal gliomatosis is discussed in relation to a single case studied in detail. Histology showed extensive subarachnoid spread of tumour that seemed to originate in an astrocytoma of the ventricular wall. The spinal fluid was xanthochromic with a high protein content. Reports of primary leptomeningeal gliomatosis are reviewed and the need for detailed histological study of the brain in such cases is emphasised.
Ashworth
B
B
Department of Clinical Neurosciences, University of Edinburgh, UK.
Gordon
A
A
D000368:Aged; D001254:Astrocytoma / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology; D005260:Female; D005910:Glioma / Q000473:pathology*; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D013346:Subarachnoid Space / Q000473:pathology