title: Complete resolution of breast cancer bone metastasis through the use of beta-interferon and tamoxifen.
abstract: A case report is described referring to a patient affected by single bone metastasis to the cranium from breast cancer. A traditional pharmacological approach was tried but proved clinically disappointing, though radiological and scintigraphic investigation confirmed a complete regression of the metastasis following a combined therapy with beta-interferon and tamoxifen for six months. Results suggest that beta-interferon and tamoxifen may offer an alternative effective approach in treating metastatic breast cancer.
authors.affiliation: Instituto di Tecnologie Biomediche del CNR, Roma.
authors.forename: C
authors.initials: C
authors.lastname: Campisi
authors.forename: S
authors.initials: S
authors.lastname: Terenzi
authors.forename: A
authors.initials: A
authors.lastname: Bandierini
authors.forename: L
authors.initials: L
authors.lastname: Ferrone
authors.forename: A
authors.initials: A
authors.lastname: Mozzicafreddo
authors.forename: M
authors.initials: M
authors.lastname: Raffaele
authors.forename: A
authors.initials: A
authors.lastname: Zappala
authors.forename: S
authors.initials: S
authors.lastname: Tomao
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D016899:Interferon-beta / Q000008:administration & dosage*; D013629:Tamoxifen / Q000008:administration & dosage*
chemical_list: D013629:Tamoxifen; D016899:Interferon-beta