Leukocyte response to administration of corticosteroid in healthy black children with neutropenia.
After a challenge with corticosteroid, increments in the absolute neutrophil count were > 50% in eight healthy black children with neutropenia, and > 2.0 x 10(9)/L (> 2000/mm3) in all but one child. Decrements in the absolute lymphocyte count mirrored the increments. Stimulation with hydrocortisone may be useful in characterizing ethnic neutropenia.
Haddy
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TB
Department of Pediatrics and Child Health, Howard University College of Medicine, Washington, D.C.
Rana
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SR
D000293:Adolescent; D044383:Black People; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000494:pharmacology*; D007223:Infant; D007958:Leukocyte Count / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D009503:Neutropenia / Q000097:blood / Q000208:ethnology* / Q000276:immunology; D009504:Neutrophils / Q000187:drug effects*; D012016:Reference Values
D006854:Hydrocortisone