Degradation of the antiarthritic prodrug, 3-carboxy-5-methyl-N-[4-(trifluoromethoxy)phenyl]-4-isoxazolecarboxamid e, in aqueous solution.
Brandl
M
M
Institute of Pharmaceutical Sciences Syntex Research, Palo Alto, California 94304.
Kennedy
J A
JA
D000814:Aniline Compounds / Q000737:chemistry* / Q000493:pharmacokinetics; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D006885:Hydroxybutyrates / Q000737:chemistry* / Q000493:pharmacokinetics; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011355:Prodrugs / Q000737:chemistry* / Q000493:pharmacokinetics; D012995:Solubility; D014867:Water
D000814:Aniline Compounds; D006885:Hydroxybutyrates; D011355:Prodrugs; D014867:Water; C073586:3-carboxy-5-methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide