title: Posterior capsule opacification in extracapsular cataract extraction and the triple procedure: a comparative study.
abstract: We retrospectively studied 330 consecutive cases, comparing the incidence of posterior capsule opacification after 279 extracapsular cataract extractions (ECCEs) or phacoemulsifications and posterior chamber intraocular lens (PC-IOL) insertions, with the incidence of opacification following 51 combined corneal transplantations, cataract extractions, and PC-IOL insertions (ie, triple procedures). Opacification developed less frequently following the triple procedure than after cataract extraction alone (9.8% vs 36.2%, respectively; P < .001). Opacification also developed later following the triple procedure. The mean length of time before capsular opacification after cataract extraction alone was 24.3 months, while a mean of 45.6 months elapsed before opacification developed after the triple procedures (P < .05). Delineation of the mechanisms contributing to these outcome differences may provide a means of reducing the incidence of or preventing posterior capsule opacification after cataract surgery.
authors.affiliation: Department of Ophthalmology, Ohio State University College of Medicine, Columbus.
authors.forename: M E
authors.initials: ME
authors.lastname: Dangel
authors.forename: S M
authors.initials: SM
authors.lastname: Kirkham
authors.forename: M J
authors.initials: MJ
authors.lastname: Phipps
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002386:Cataract / Q000209:etiology*; D002387:Cataract Extraction / Q000009:adverse effects* / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D015948:Keratoplasty, Penetrating / Q000009:adverse effects* / Q000379:methods; D007903:Lens Capsule, Crystalline; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies