title: Binding and internalization of microorganisms by integrin receptors.
abstract: Many microbial pathogens bind host-cell integrin receptors. These interactions are promoted either by a host protein binding the microorganism or by a surface-localized ligand encoded by the pathogen. Attachment facilitates extracellular adhesion of the microorganism or internalization by the host cell.
authors.affiliation: Howard Hughes Medical Institute, Boston, MA.
authors.forename: R R
authors.initials: RR
authors.lastname: Isberg
authors.forename: G
authors.initials: G
authors.lastname: Tran Van Nhieu
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001419:Bacteria / Q000378:metabolism; D056890:Eukaryota / Q000378:metabolism; D006801:Humans; D016023:Integrins / Q000378:metabolism*; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D014780:Viruses / Q000378:metabolism
chemical_list: D016023:Integrins; D009842:Oligopeptides; D010455:Peptides; C047981:arginyl-glycyl-aspartic acid