Repeated large-dose haptoglobin therapy in an extensively burned patient: case report.
The case of a 24-year-old man who sustained a 100% body surface area burn and inhalation injury is presented. Hemoglobinuria reappeared 2 hours after haptoglobin was first administered. In addition to individualized fluid resuscitation and plasma administration, a large dose of haptoglobin was repeatedly administered while we monitored for occult blood in the centrifuged urine. As a result, postburn shock and acute renal failure were prevented.
Imaizumi
H
H
Department of Traumatology and Critical Care Medicine, Sapporo Medical University, School of Medicine, Japan.
Tsunoda
K
K
Ichimiya
N
N
Okamoto
T
T
Namiki
A
A
D058186:Acute Kidney Injury / Q000503:physiopathology / Q000517:prevention & control*; D000328:Adult; D002056:Burns / Q000150:complications / Q000628:therapy*; D002059:Burns, Inhalation / Q000628:therapy; D006242:Haptoglobins / Q000627:therapeutic use*; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D012151:Resuscitation; D012774:Shock, Traumatic / Q000517:prevention & control*
D006242:Haptoglobins