Volumetric analysis of epilepsy surgery resections using high resolution magnetic imaging: technical report.
A method is described for accurately measuring the volume and site of epilepsy surgery resections utilizing magnetic resonance imaging. Accuracy has been assessed using post-mortem studies, and both the intra- and interobserver variability is consistently less than 5%. The technique has so far been applied to 25 patients following a variety of operations for medically intractable epilepsy. It provides the crucially accurate baseline required for meaningful follow-up outcome studies of epilepsy surgery. Consequently, it should allow the development of more precise prognostic indices for such operations.
Kitchen
N D
ND
Department of Neurological Surgery, Institute of Neurology, London, UK.
Thomas
D G
DG
Shorvon
S D
SD
Fish
D R
DR
Stevens
J M
JM
D001921:Brain / Q000473:pathology* / Q000601:surgery; D004827:Epilepsy / Q000175:diagnosis / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D015588:Observer Variation; D011237:Predictive Value of Tests; D011379:Prognosis; D012016:Reference Values