title: Angina pectoris associated with ST segment elevation in the absence of epicardial coronary arterial obstruction. Case reports.
abstract: Two cases are presented in which angina pectoris associated with ST segment elevation occurred during either an ergonovine provocation test or coronary angioplasty, despite the absence of epicardial coronary artery obstruction. In both cases, no epicardial coronary spasm, thromboembolic occlusion, coronary air embolus, vessel dissection, or side-branch occlusion was observed. These findings suggest that transmural myocardial ischemia without epicardial coronary artery obstruction can occur owing to abnormalities of the coronary microcirculation. Microvascular vasoconstriction leading to transmural myocardial ischemia may be induced by ergonovine or by the release of potent vasoconstrictors from disrupted coronary lesions during angioplasty.
authors.affiliation: 1st Department of Internal Medicine, Kanazawa University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nagai
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamura
authors.forename: S
authors.initials: S
authors.lastname: Takata
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
mesh_terms: D000787:Angina Pectoris / Q000175:diagnosis* / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis*; D004562:Electrocardiography / Q000187:drug effects; D004874:Ergonovine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D004874:Ergonovine