[Purification and standardization of allergens].
Allergen preparations cannot be compared with any other class of drugs. Their compositions are as varied as the raw materials that induce sensitisation and their biological activities are as variable as the individual immunological profiles of patients. They are obtained by extraction and therefore very dependent on the methods used, based on known principles. The multiplicity of the allergens they contain have mostly not yet been characterised and this does not allow individual measurement. Standardisation of the allergen preparations is done mostly by comparison of their overall activity with that of a reference preparation. This is expressed in arbitrary units or in units of biological activity determined on representative mean populations of allergic subjects.
Guérin
B
B
D000485:Allergens / Q000008:administration & dosage / Q000302:isolation & purification*; D003888:Desensitization, Immunologic / Q000592:standards; D006801:Humans; D012016:Reference Values
D000485:Allergens
Purification et standardisation des allergènes.