Mononucleosis caused by Epstein-Barr virus and cytomegalovirus in children: a comparative study of 124 cases.
We present 124 children who had mononucleosis. The patients were selected according to strict clinical features. Twenty (16.1%) of the 124 children were proved to have cytomegalovirus mononucleosis and 104 (83.8%) children had Epstein-Barr virus mononucleosis. The symptoms were similar in both groups. Significant differences were found only for the presence of cervical lymphadenopathy, which was more frequent in the Epstein-Barr group (83.2%) compared with the cytomegalovirus group (75%). Fever was the most frequent symptom in both groups. Cytomegalovirus mononucleosis was significantly more frequent in children younger than 4 years.
Lajo
A
A
La Paz Children's Hospital, Autonoma University of Madrid, Spain.
Borque
C
C
Del Castillo
F
F
Martín-Ancel
A
A
D000367:Age Factors; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003587:Cytomegalovirus; D005260:Female; D004854:Herpesvirus 4, Human; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D007231:Infant, Newborn; D007244:Infectious Mononucleosis / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D008297:Male
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M