Progression of multifocal motor neuropathy during apparently successful treatment with human immunoglobulin.
We report a patient with multifocal motor neuropathy (MMN) who experienced a paradoxical decline in baseline strength to below pretreatment levels during a period of improvement associated with human immunoglobulin (HIG) administration. This outcome suggests that HIG may not limit progression of MMN and may reduce the utility of HIG as chronic therapy.
Elliott
J L
JL
Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110.
Pestronk
A
A
D006801:Humans; D016756:Immunoglobulins, Intravenous; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D009422:Nervous System Diseases / Q000628:therapy*
D016756:Immunoglobulins, Intravenous