The prevalence of inducible beta-lactamase in clinical isolates of Yersinia enterocolitica.
In a prevalence study, 100 clinical isolates of Yersinia enterocolitica belonging to biotypes 1A, 3 and 4 isolated in Australia were examined for the induction of beta-lactamase in broth at 28 degrees C using imipenem as an inducer. An increase in beta-lactamase activity ranging from 15 to 93 fold was observed with all 36 isolates of biotypes 1A and 3 confirming that both enzyme B and enzyme "B-like" in biotype 3 and biotype 1A Yersinia enterocolitica were readily inducible. By contrast, imipenem failed to induce beta-lactamase in any of the 64 isolates of Yersinia enterocolitica belonging to biotype 4.
Pham
J N
JN
Department of Microbiology, Prince of Wales Hospital, Randwick, New South Wales.
Bell
S M
SM
D004790:Enzyme Induction; D006801:Humans; D007525:Isoelectric Focusing; D015008:Yersinia enterocolitica / Q000201:enzymology* / Q000302:isolation & purification; D001618:beta-Lactamases / Q000096:biosynthesis*
D001618:beta-Lactamases