Application of electron microscopy and immunocytochemistry in lung cancer diagnosis.
Using bronchofiberoscopy the biopsies of '50 small cell carcinomas of the lung (SCLC) were diagnosed. The material was studied by immunocytochemical methods for cytokeratins and in routine transmission electron microscopy. The presence of bundles of cytokeratins was specific for squamous epithelium, in all histological subtypes of small cell carcinomas. The number and distribution of cytokeratins were described. In whole material we found the neuroendocrine cells in which polymorphic neuroendocrine granules were present.
Przybyłowski
P
P
Department of Clinical Pathomorphology, University Academy of Medicine, Poznań.
Młynarczyk
W
W
Błotna-Filipiak
M
M
Biczysko
W
W
D018288:Carcinoma, Small Cell / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology*; D008854:Microscopy, Electron