Interleukin-1 receptor antagonist is not detrimental to human islet cell insulin secretion but decreases insulin content.
Strumph
P S
PS
Department of Medicine, University of Pittsburgh, Pennsylvania.
Carty
S E
SE
Rilo
H L
HL
Carroll
P B
PB
Ricordi
C
C
Lotze
M T
MT
D000328:Adult; D002102:Cadaver; D002469:Cell Separation; D002478:Cells, Cultured; D046508:Culture Techniques / Q000379:methods; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D053590:Interleukin 1 Receptor Antagonist Protein; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism; D007700:Kinetics; D017472:Receptors, Interleukin-1 / Q000037:antagonists & inhibitors*; D011994:Recombinant Proteins / Q000494:pharmacology; D012795:Sialoglycoproteins / Q000494:pharmacology*; D014019:Tissue Donors
C507763:IL1RN protein, human; D007328:Insulin; D053590:Interleukin 1 Receptor Antagonist Protein; D017472:Receptors, Interleukin-1; D011994:Recombinant Proteins; D012795:Sialoglycoproteins