title: [Experience with rocephin in orthopedic practice].
abstract: Authors report on the results of Rocephin prophylaxis in 30 total prostheses. The dose of the preparation was 2g/day. It was given 3 times in intravenous drop infusion 1-1.5 hours before the operation and on the second and third day. The drains were then removed. During 1 year observation no wound infection was observed. As a postoperative complication exacerbation of chronic bronchitis, existing already since years, was found. This however healed after 5 and 6 days of Rocephin and expectorant treatment. As side effect of the medicament, in single cases, vomiting, stomatitis, thrombocytopenia and allergic dermatitis were observed. It is stated, based on own experience, that the broad spectrum Rocephin, belonging to the third generation cephalosporins, securing a 24 hours bactericide activity, is suitable in a single 2g dose/day in hip endoprosthesis to prevent postoperative infections.
authors.affiliation: Debreceni Orvostudományi Egyetem Ortopédiai Klinika közleménye.
authors.forename: G
authors.initials: G
authors.lastname: Szücs
authors.forename: J
authors.initials: J
authors.lastname: Rigó
authors.forename: S
authors.initials: S
authors.lastname: Bene
authors.forename: T
authors.initials: T
authors.lastname: Simon
mesh_terms: D000368:Aged; D002443:Ceftriaxone / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D013530:Surgical Wound Infection / Q000517:prevention & control
chemical_list: D002443:Ceftriaxone
vernacular_title: Rocephinnel szerzett tapasztalatok az ortopédiai gyakorlatban.