[Biochemical mechanisms of the effect of prostaglandin E2 on the effect of parenteral nitrogenous nutrition].
Activation of lipid peroxidation (LPP) processes in the hepatocytes of animals suffering from toxic hepatitis leads to disorders of membrane function and causes disorders of transports processes (activity of adenosine triphosphatase, active sodium transport) in them. Administration of prostaglandin E2 (PGE2) as a potent antioxidant simultaneously with casein hydrolysate to animals with experimental pathology intensifies the effect of the nitrous preparation and promotes normalization of the studied processes (LPP, adenosine triphosphatase activity, active sodium transport). Thus, through its action on LPP and the transport systems, PGE2 influences the effect of casein hydrolysate.
Glants
R M
RM
Liubinets
L A
LA
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D015232:Dinoprostone / Q000494:pharmacology*; D005260:Female; D008297:Male; D009584:Nitrogen / Q000008:administration & dosage*; D010288:Parenteral Nutrition; D051381:Rats
D015232:Dinoprostone; D009584:Nitrogen
Nekotorye biokhimicheskie mekhanizmy vliiania prostaglandina E2 na éffekty parenteral'nogo azotistogo pitaniia.