Assignment of two alpha 2 adrenoceptor subtype genes to murine chromosomes.
Subtype-specific probes to the murine homologs of the human ADRA2B and ADRA2C genes were prepared by PCR amplification and used to map these two genes to mouse chromosomes 2 and 5, respectively. Both genes mapped in regions of mouse chromosomes consistent with their map location in humans. These mapping results provide additional insights into the linkage relationships among members of this important gene family.
Chang
N C
NC
Institute of Microbiology and Immunology, National Yang-Ming Medical College, Taipei, Taiwan, ROC.
Jenkins
N A
NA
Gilbert
D J
DJ
Copeland
N G
NG
Chang
Y H
YH
Chen
W M
WM
Chang
A C
AC
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D005796:Genes; D006801:Humans; D006824:Hybridization, Genetic; D051379:Mice; D008810:Mice, Inbred C57BL; D015335:Molecular Probes / Q000235:genetics; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011942:Receptors, Adrenergic, alpha / Q000235:genetics*; D017385:Sequence Homology
D015335:Molecular Probes; D011942:Receptors, Adrenergic, alpha