Evaluation of serum zinc-binding capacity during childbirth, in newborn infants and during the menstrual cycle.
This is a study of the value of total serum zinc, serum zinc per g of protein, serum zinc-binding capacity and serum zinc-binding capacity per g of protein in 102 pregnant women during childbirth and in the cord blood of their newborn infants. A control group is established by analyzing these parameters in 10 healthy non-pregnant women on the first day of menstruation and on the day of ovulation during two consecutive menstrual cycles. The total serum zinc and serum zinc per g of protein values found were significantly higher in cord blood than in maternal blood, and the binding capacity of zinc and of zinc per g protein were significantly higher in maternal blood. There is a negative correlation between total zinc and binding capacity and total zinc and binding capacity per g protein both in maternal and in cord blood. In the control group, the values of total zinc and zinc per g protein vary from one menstrual cycle to the next and between the different phases of each cycle. Zinc-binding capacity per g protein during ovulation is significantly lower than during menstruation. These results allow us to conclude that the rise of zinc-binding capacity and zinc-binding capacity per g protein in maternal blood during childbirth, and during menstruation in the control group, can be due to the effect of progesterone. The fact that zinc-binding capacity and zinc-binding capacity per g of protein are higher in maternal blood than in cord blood would confirm the existence of mechanisms which tend to increase binding of zinc in the fetus.
Turull
M R
MR
Consorci Hospitalari Parc Tauli, Area Pediatrica, Sabadell, Barcelona, Spain.
Argemi
J
J
Gutierrez
C
C
Lechuga
J L
JL
Torra
M
M
D000328:Adult; D001798:Blood Proteins / Q000378:metabolism; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007743:Labor, Obstetric / Q000097:blood*; D008297:Male; D008597:Menstrual Cycle / Q000097:blood*; D010060:Ovulation / Q000502:physiology; D011247:Pregnancy; D011485:Protein Binding; D012016:Reference Values; D015032:Zinc / Q000097:blood*
D001798:Blood Proteins; D015032:Zinc