title: Biosynthesis of Tcr-alpha, beta and Tcr-gamma, delta/CD3 complexes.
abstract: Jurkat J76 clone, LYON L12.37 clone and L12.37 cells transfected with J76-alpha cDNA or J76 Tcr-alpha mutated cDNA (J79) were analysed for membrane expression of Tcr/CD3 complex using WT31 mAb (Tcr-alpha, beta) or Tcr-delta 1 mAb (Tcr-gamma, delta): LYON cells express V beta 9 bearing Tcr-beta chains. J76 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-gamma, delta chains and J79 Tcr-alpha cDNA transfected LYON cells have intracellular Tcr-alpha (M), beta chains.
authors.affiliation: Laboratoire d'Immunologie Cellulaire et Moleculaire, CRPG/CNRS, Chu de Purpan, Toulouse.
authors.forename: S
authors.initials: S
authors.lastname: Bauguil-Caspar
authors.forename: J
authors.initials: J
authors.lastname: Arnaud
authors.forename: J
authors.initials: J
authors.lastname: Kuhlmann
authors.forename: C
authors.initials: C
authors.lastname: Geisler
authors.forename: B
authors.initials: B
authors.lastname: Rubin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017252:CD3 Complex / Q000096:biosynthesis* / Q000235:genetics; D002999:Clone Cells / Q000276:immunology; D017124:Conserved Sequence; D018076:DNA, Complementary / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D017354:Point Mutation; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000096:biosynthesis* / Q000235:genetics; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000096:biosynthesis* / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D014162:Transfection
chemical_list: D017252:CD3 Complex; D018076:DNA, Complementary; D016693:Receptors, Antigen, T-Cell, alpha-beta; D016692:Receptors, Antigen, T-Cell, gamma-delta