Sarcoid-like granuloma following prolonged etretinate treatment.
We report on a patient in whom prolonged therapy with etretinate was associated with the appearance of disseminated nodules, whose histopathologic study showed a sarcoid-like granuloma. Although the role of etretinate in the occurrence of this granulomatous reaction is not proven, we speculate on possible mechanisms of such a link.
Fernández-Redondo
V
V
Department of Dermatology, General Hospital of Galicia, Faculty of Medicine, Santiago de Compostela, Spain.
Vázquez
J
J
Sánchez-Aguilar
D
D
Toribio
J
J
D005050:Etretinate / Q000009:adverse effects* / Q000627:therapeutic use; D006099:Granuloma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D013997:Time Factors
D005050:Etretinate