A comparison of in vitro fertilization results after embryo transfer after 2, 3, and 4 days of embryo culture.
Embryo transfer results after a 2 to 4 day period of embryo culture were compared. Two thousand two hundred ninety-seven ETs, performed in 1991 and 1992, were analyzed. Ongoing pregnancy rates after 2, 3, or 4 days of embryo culture were 23.3%, 21.9%, and 26.4%, respectively. Multiple pregnancy rates were 36.2%, 38.8%, and 32.6% per ongoing pregnancy for the three groups, respectively. The implantation rate of 73 cavitating morulae on day 4 was surprisingly high (41%) compared with that of other developmental stages. Transfer after 4 days of culture gives the ability to recognize embryos with a very high implantation potential.
Huisman
G J
GJ
Department of Obstetrics and Gynaecologie, Academic Hospital Rotterdam, Dijkzigt, The Netherlands.
Alberda
A T
AT
Leerentveld
R A
RA
Verhoeff
A
A
Zeilmaker
G H
GH
D002478:Cells, Cultured; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000166:cytology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011446:Prospective Studies; D013997:Time Factors