Bronchiolitis associated with the finding of the fungus aspergillus. Report of two cases.
We report two cases of necrotizing bronchiolitis and bronchiolitis obliterans associated with the finding of the fungus aspergillus. One of the cases also showed bronchiolocentric granulomas and mucoid impaction of a segmental bronchus. Both patients were immunocompromised and had presented with dyspnea, cough, fever, and pulmonary infiltrates. Systemic antifungal therapy led to symptomatic and radiologic resolution. We surmise that these cases represent unusual examples of chronic necrotizing aspergillosis. The spectrum of pulmonary aspergillus diseases is reviewed.
Sieber
S C
SC
Hartford Hospital, CT.
Cole
S R
SR
McNab
J M
JM
Shore
E
E
D000368:Aged; D001228:Aspergillosis / Q000473:pathology*; D001988:Bronchiolitis / Q000382:microbiology* / Q000473:pathology; D001989:Bronchiolitis Obliterans / Q000382:microbiology* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D009336:Necrosis