Reversible monocular blindness complicating Churg-Strauss syndrome.
A 76-year-old woman hospitalized for treatment of an inferior vena cava thrombus was noted to have eosinophilia as well as asthma, peripheral neuropathy, jaw claudication and visual loss. Pathological review of a temporal artery biopsy revealed vasculitis with eosinophils but no giant cells. Treatment with high dose corticosteroids resulted in improvement of visual acuity from hand motion to 20/60. Whereas at least 6 cases of temporal artery involvement with Churg-Strauss syndrome have been reported, visual loss has occurred in only 3 patients. In each of these cases, visual loss was permanent.
Alberts
A R
AR
Division of Rheumatology and Allergy-Clinical Immunology, North Shore University Hospital, Manhasset, New York 11030.
Lasonde
R
R
Ackerman
K R
KR
Chartash
E K
EK
Susin
M
M
Furie
R A
RA
D000368:Aged; D001766:Blindness / Q000188:drug therapy / Q000209:etiology*; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications / Q000473:pathology; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage; D011239:Prednisolone / Q000008:administration & dosage
D011239:Prednisolone; D008775:Methylprednisolone