Neurofibromatosis, acute myelomonocytic leukemia, and disseminated tuberculosis: an adult case report.
Leukemia associated with neurofibromatosis has been reported to be predominantly nonlymphocytic and limited to childhood; it is rare in adulthood. An adult case is reported; the patient had nonfamilial peripheral neurofibromatosis (NF) (von Recklinghausen's disease), contracted acute myelomonocytic leukemia and disseminated tuberculosis (TB). After a four-month periods of anti-TB medication that disease was much improved, but the leukemic picture was still progressing. Chemotherapy was not given. This case further illustrated an association between acute nonlymphocytic leukemia (ANLL) and neurofibromatosis type 1 (NF-1) in adulthood. An attempt was made also to explain the relationship between disseminated tuberculosis and, in this instance, hematological abnormalities.
Chiou
S C
SC
Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan, R.O.C.
Hwang
W L
WL
Chen
M C
MC
Gau
J P
JP
D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000150:complications*; D008297:Male; D008875:Middle Aged; D017253:Neurofibromatoses / Q000150:complications*; D014376:Tuberculosis / Q000150:complications*