title: Sphenoid and cavernous sinuses involvement as first site of metastasis from a fallopian tube carcinoma. Case report.
abstract: The occurrence of central nervous system metastases in ovarian cancer patients ranges from 0.88 to 4.5%. Centra nervous system involvement in a fallopian tube carcinoma is extremely rare. A 77-year-old woman with an invasive tubal carcinoma was admitted because of ophthalmoplegia, sparing the lateral rectus muscle of the left eye, a decreased left corneal reflex and hypoesthesia along the distribution of the ophthalmic and maxillary branches of the left trigeminal nerve. CT scan showed a space occupying lesion in the left sphenoid sinus invading the left cavernous sinus and the submucosa of the left lateral wall of the nasopharynx, proven histologically to be a metastasis from her primary cancer. Attention should be paid to the possibility of distant and unusual metastases associated with tubal cancer in order to treat the patients promptly.
authors.affiliation: Department of Oncology, Tel Aviv Sourasky Medical Center, Israel.
authors.forename: O
authors.initials: O
authors.lastname: Merimsky
authors.forename: M
authors.initials: M
authors.lastname: Inbar
authors.forename: I
authors.initials: I
authors.lastname: Groswasser-Reider
authors.forename: M
authors.initials: M
authors.lastname: Neudorfer
authors.forename: S
authors.initials: S
authors.lastname: Chaitchik
mesh_terms: D000368:Aged; D002291:Carcinoma, Papillary / Q000556:secondary*; D002426:Cavernous Sinus / Q000473:pathology*; D005185:Fallopian Tube Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D009303:Nasopharyngeal Neoplasms / Q000473:pathology; D009336:Necrosis; D009361:Neoplasm Invasiveness; D010255:Paranasal Sinus Neoplasms / Q000556:secondary*; D012888:Skull Neoplasms / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000556:secondary*; D014652:Vascular Diseases / Q000473:pathology