title: [Clinical efficacy of cefixime (results of multicenter trials)].
abstract: Multicentre trials of cefixime (Cefspan, Fujisawa Pharmaceutical Co., Ltd., Japan) were performed in 1992. The trials involved 137 children and 269 adult patients with inflammatory infections of the respiratory organs and urinary tracts and otorhinolaryngologic affections. Positive clinical and bacteriological results of the trials were stated in 76-90 per cent of the cases. The adverse reactions such as skin eruption and dyspepsia were rare and did not require the specific treatment.
authors.forename: E V
authors.initials: EV
authors.lastname: Sereda
authors.forename: V A
authors.initials: VA
authors.lastname: Gusel'
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Feshchenko
authors.forename: A K
authors.initials: AK
authors.lastname: Ustinovich
authors.forename: V K
authors.initials: VK
authors.lastname: Zubovich
authors.forename: V I
authors.initials: VI
authors.lastname: Trofimov
authors.forename: A V
authors.initials: AV
authors.lastname: Nedostup
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Ovchinnikov
authors.forename: M S
authors.initials: MS
authors.lastname: Pluzhnikov
authors.forename: A F
authors.initials: AF
authors.lastname: Darenkov
mesh_terms: D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000627:therapeutic use*; D020682:Cefixime; D002439:Cefotaxime / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007249:Inflammation / Q000188:drug therapy; D010038:Otorhinolaryngologic Diseases / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D000890:Anti-Infective Agents; D020682:Cefixime; D002439:Cefotaxime
vernacular_title: Klinicheskaia éffektivnost' tsefiksima (rezultaty mul'titsentrovykh ispytaniĭ.