Impairment of ristocetin-induced platelet aggregation in patients with infective endocarditis.
An investigation was carried out on two patients with infective endocarditis associated with reduction of ristocetin-induced aggregation of platelets. The plasma of these patients reduced the aggregability with ristocetin of normal platelets. It is suggested that the patients had certain plasma factors which disturbed platelet aggregation with ristocetin.
Matsumoto
M
M
Third Department of Internal Medicine, Gunma University School of Medicine, Japan.
Murakami
H
H
Matsushima
T
T
Tamura
J
J
Sadakata
H
H
Narahara
N
N
Sawamura
M
M
Naruse
T
T
Tsuchiya
J
J
D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000097:blood* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects*; D012310:Ristocetin / Q000494:pharmacology*
D012310:Ristocetin; D000667:Ampicillin