Diuretic action of an aqueous extract of Lepidium latifolium L.
An aqueous extract of Lepidium latifolium L. given orally and intraperitoneally considerably enhanced urinary excretion (UV) in rats with respect to control groups. A slight increase in ion excretion was also observed. Other parameters such as specific gravity, nitrite, pH, glucose, ketone bodies, urobilinogen, and blood were also studied. A good correlation for the dosage rat/man for the aqueous extract was achieved.
Navarro
E
E
Departamento de Farmacología, Facultad de Medicina, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
Alonso
J
J
Rodriguez
R
R
Trujillo
J
J
Boada
J
J
D000284:Administration, Oral; D000818:Animals; D004232:Diuretics / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006863:Hydrogen-Ion Concentration; D007274:Injections, Intraperitoneal; D010936:Plant Extracts / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D011188:Potassium / Q000652:urine; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000652:urine
D004232:Diuretics; D010936:Plant Extracts; D012964:Sodium; D011188:Potassium