Cytogenetic findings in two basal cell carcinomas.
We describe the cytogenetic study of two basal cell carcinomas. Only single chromosomally abnormal clones could be detected in both. In addition, many nonclonal changes were seen in the samples, which may represent small neoplastic clones or the result of a basic molecular defect induced by carcinogens.
Kawasaki-Oyama
R S
RS
Departmento de Biologia, Letras e Ciências Exatas-UNESP, São José do Rio Preto, SP, Brazil.
André
F S
FS
Caldeira
L F
LF
Castilho
W H
WH
Gasques
J A
JA
Bozola
A R
AR
Thomé
J A
JA
Tajara
E H
EH
D000368:Aged; D002280:Basal Cell Carcinoma / Q000235:genetics*; D002869:Chromosome Aberrations / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000235:genetics*