title: Carpentier-Edwards standard and supra-annular porcine bioprostheses: 10 year comparison of structural valve deterioration.
abstract: From 1975 to 1986 the Carpentier-Edwards standard (CE-S) and supra-annular (CE-SAV) porcine bioprostheses were implanted in 1213 and 1000 patients, respectively. The mean age of the standard group was 57.6 years (range 8 to 85 years) while in the supra-annular group it was 60.7 years (range 13 to 85 years). The freedom from structural valve deterioration (SVD) at 10 years for the entire patient population was 79.4% +/- 3.1% with CE-SAV and 76.1% +/- 1.6% with CE-S (p < 0.05). The overall freedom from SVD for those patients undergoing mitral valve replacement (MVR) was 74.5% +/- 4.6% for CE-SAV and 68.7% +/- 2.8% for CE-S (p = NS), while for those undergoing aortic valve replacement (AVR) it was 86.5% +/- 4.3% for CE-SAV and 84.1% +/- 2.0% for CE-S (p = NS). In those patients under 35 years of age undergoing MVR, the freedom from SVD for CE-SAV and CE-S was 94.4% +/- 5.4% and 62.9% +/- 8.6%, respectively (p < 0.05 at 8 years); for those aged 36-50 years, it was 75.6% +/- 7.4% and 61.7% +/- 6.0%; for those aged 51-65 years, it was 76.2% +/- 7.4% and 69.6% +/- 4.2%; for those over 65 years, it was 74.1% +/- 7.1% and 82.2% +/- 5.2%; for those aged 65-69 years, it was 70.2% +/- 8.7% and 63.7% +/- 8.1%; and for those over 70 years of age, it was 79.2% +/- 8.7% and 95.3% +/- 3.2%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: University of British Columbia, Vancouver, Canada.
authors.forename: W R
authors.initials: WR
authors.lastname: Jamieson
authors.forename: L H
authors.initials: LH
authors.lastname: Burr
authors.forename: G F
authors.initials: GF
authors.lastname: Tyers
authors.forename: A I
authors.initials: AI
authors.lastname: Munro
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000601:surgery; D001705:Bioprosthesis; D002648:Child; D002675:Child, Preschool; D006349:Heart Valve Diseases / Q000601:surgery; D006350:Heart Valve Prosthesis; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D011474:Prosthesis Design; D011475:Prosthesis Failure; D013997:Time Factors