Structure-activity relationships of new taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.
Ojima
I
I
Department of Chemistry, State University of New York at Stony Brook 11794-3400.
Park
Y H
YH
Sun
C M
CM
Fenoglio
I
I
Appendino
G
G
Pera
P
P
Bernacki
R J
RJ
D000470:Alkaloids / Q000138:chemical synthesis / Q000494:pharmacology*; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D008958:Models, Molecular; D013329:Structure-Activity Relationship; D043823:Taxoids; D014315:Triterpenes / Q000138:chemical synthesis / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D014315:Triterpenes; C073950:baccatin III; C042213:10-deacetylbaccatine III