Anti-inflammatory activity of Sideritis javalambrensis extracts.
Hexane, dichloromethane, ethyl acetate and methanol extracts of Sideritis javalambrensis Pau were examined for their anti-inflammatory activity against adjuvant-carrageenan-induced inflammation and compared with phenylbutazone. In the chronic stage of inflammation, the hexane and methanol extracts showed the greatest inhibitory activity. None of the extracts inhibited inflammation in the acute phase.
de las Heras
B
B
Department of Pharmacology, Faculty of Pharmacy, Universidad Complutense de Madrid, Spain.
Vivas
J M
JM
Villar
A
A
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000302:isolation & purification* / Q000627:therapeutic use*; D002351:Carrageenan; D004195:Disease Models, Animal; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000302:isolation & purification* / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D002351:Carrageenan