title: Pregnancy-induced hypertensive disorders.
abstract: The concept that endothelial cell activation and injury constitutes the key pathogenetic event is receiving increasing support, but the causative factor or factors are, as yet, unclear. The search for a reliable and clinically useful test to identify pregnant women at risk continues. No definitive conclusions can yet be drawn as to the efficacy and safety of low-dose aspirin prophylaxis. Monitoring of maternal-fetal condition, careful consideration of maternal and perinatal risks, and a balanced decision to continue or terminate pregnancy are key elements of clinical management.
authors.affiliation: Institute of Obstetrics and Gynecology, Erasmus University Medical School, Rotterdam, The Netherlands.
authors.forename: H C
authors.initials: HC
authors.lastname: Wallenburg
authors.forename: W
authors.initials: W
authors.lastname: Visser
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D004730:Endothelium, Vascular / Q000293:injuries; D005260:Female; D005323:Fetal Monitoring; D006801:Humans; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D011247:Pregnancy; D011295:Prenatal Care / Q000379:methods; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents; D001241:Aspirin