[Cerebral blood circulation during angiotensin-converting enzyme inhibition].
The inhibitor of angiotensin-converting enzyme captopril does not change the tone of the brain vessels but decreases the blood pressure and the tone of peripheral vessels, increases the oxygen and glucose demand in the brain in intact cats. In animals with brain ischemia, captopril decreased the tone of the brain vessels and promoted normalising of metabolic and transcapillary exchange in the brain.
Gaevyĭ
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M N
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D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001921:Brain / Q000098:blood supply / Q000187:drug effects / Q000378:metabolism; D002196:Capillaries / Q000187:drug effects / Q000378:metabolism; D002216:Captopril / Q000494:pharmacology* / Q000627:therapeutic use; D002415:Cats; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004353:Drug Evaluation, Preclinical; D005947:Glucose / Q000378:metabolism; D002546:Ischemic Attack, Transient / Q000188:drug therapy / Q000503:physiopathology; D010101:Oxygen Consumption / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects
D002216:Captopril; D005947:Glucose
Mozgovoe krovoobrashchenie v usloviiakh ingibirovaniia angiotenzin-konvertiruiushchego fermenta.