title: The Mattis Dementia Rating Scale: normative data from 1,001 healthy volunteers.
abstract: We administered the Mattis Dementia Rating Scale (MDRS) to 1,001 healthy volunteers, aged 50 to 80 years, randomly selected from our community. Multivariate regression analysis revealed educational level (p = 0.000004) and age (p = 0.00001), but no other sociodemographic or risk factors for stroke, to be significantly associated with the MDRS score. The age- and education-specific lowest quintile cutoff scores ranged from 140 in subjects aged 50 to 59 years with at least college experience to 130 in subjects aged 70 to 80 years with only 4 to 9 years of schooling. These percentile distributions obtained for decades of age and different levels of education should be useful reference values for clinicians and investigators when applying the MDRS to assess cognitive functioning.
authors.affiliation: Department of Neurology, Karl-Franzens University Graz, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
authors.forename: W
authors.initials: W
authors.lastname: Freidl
authors.forename: F
authors.initials: F
authors.lastname: Fazekas
authors.forename: B
authors.initials: B
authors.lastname: Reinhart
authors.forename: P
authors.initials: P
authors.lastname: Grieshofer
authors.forename: M
authors.initials: M
authors.lastname: Koch
authors.forename: B
authors.initials: B
authors.lastname: Eber
authors.forename: M
authors.initials: M
authors.lastname: Schumacher
authors.forename: K
authors.initials: K
authors.lastname: Polmin
authors.forename: H
authors.initials: H
authors.lastname: Lechner
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003704:Dementia / Q000453:epidemiology*; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D011897:Random Allocation; D012016:Reference Values