title: Coexpression of GABAA receptor gamma 1 and gamma 2 subunits in the rat trigeminal ganglion.
abstract: We examined the expression of gamma-aminobutyric acid (GABA)A receptor gamma 1 and gamma 2 subunit mRNAs in the rat trigeminal ganglion using in situ hybridization histochemistry. Most ganglion cells expressed both gamma 1 and gamma 2 mRNAs simultaneously. These findings are a marked contrast to the findings in the central nervous system where areas expressing both subunits are rare. In addition, we demonstrated using immunohistochemistry that the gamma 1 subunit is also expressed at the protein level in trigeminal ganglion neurons and fibers in the trigeminal spinal nucleus.
authors.affiliation: Department of Anatomy and Neuroscience, Osaka University Medical School, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Kondo
authors.forename: H
authors.initials: H
authors.lastname: Kiyama
authors.forename: T
authors.initials: T
authors.lastname: Araki
authors.forename: T
authors.initials: T
authors.lastname: Shida
authors.forename: Y
authors.initials: Y
authors.lastname: Ueda
authors.forename: M
authors.initials: M
authors.lastname: Tohyama
mesh_terms: D000818:Animals; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D011963:Receptors, GABA-A / Q000032:analysis*; D012668:Trigeminal Ganglion / Q000737:chemistry*
chemical_list: D011963:Receptors, GABA-A