Understanding and treating Bartter syndrome.
Most of its clinical manifestations are the result of hypokalemia. The diagnosis is one of exclusion, mainly of surreptitious vomiting and diuretic abuse. The primary cause remains unknown but the most likely candidate is reduced sodium chloride reabsorption in the thick ascending limb of Henle's loop. Current therapy focuses on multiple agents to reduce massive potassium loss.
Gordon
J A
JA
Department of Medicine, University of Iowa College of Medicine, Iowa City.
Stokes
J B
JB
D001477:Bartter Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D003937:Diagnosis, Differential; D006801:Humans; D007008:Hypokalemia / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology