title: [Quantitative determination of alpha-peroxyachifolide in yarrow by HPLC with amperometric detection].
abstract: A HPLC method with amperometric detection is established for the contact allergen alpha-peroxyachifolid (1) from yarrow (Achillea millefolium L., s. str.). The amounts of 1 are between 0.25 and 0.60% in blossoms, dried 2 h at room temperature, and between 0.01 and 0.05% in the leaves. In completely dried material and in some preparations from the market 1 could also be quantified.
authors.affiliation: Pharmazeutisches Institut, Rheinischen Friedrich-Wilhelms-Universität, Bonn.
authors.forename: G
authors.initials: G
authors.lastname: Rücker
authors.forename: M
authors.initials: M
authors.lastname: Neugebauer
authors.forename: A
authors.initials: A
authors.lastname: Kiefer
mesh_terms: D000485:Allergens / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D007783:Lactones / Q000032:analysis*; D010545:Peroxides; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000485:Allergens; D007783:Lactones; D010545:Peroxides; D012717:Sesquiterpenes; C070257:alpha-peroxyachifolid
vernacular_title: Quantitative Bestimmung von alpha-Peroxyachifolid in der Schafgarbe durch HPLC mit amperometrischer Detektion.