[The effect of a luliberin analog on the formation of alcoholic motivation in rats].
The synthetic luliberin analogue-agonist surfagon exerted a dose-dependent activating effect on formation of alcoholic motivation in white male rats. No such effect occurred in castrated rats, even though the rate of alcohol consumption was higher in the latters. The data obtained suggest a steroid-dependent mechanism of surfagon.
Sever'ianova
L A
LA
Bobyntsev
I I
II
D000428:Alcohol Drinking / Q000503:physiopathology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000494:pharmacology; D006728:Hormones / Q000494:pharmacology*; D008297:Male; D009042:Motivation; D009919:Orchiectomy; D051381:Rats; D013997:Time Factors
D006728:Hormones; D007987:Gonadotropin-Releasing Hormone; C010661:surfagon
Vliianie analoga luliberina na formirovanie alkogol'noĭ motivatsii u krys.