title: [Thrombosis of a Bjork-Shiley mitral valve prosthesis: its thrombolytic treatment with rt-PA].
abstract: A 62-year-old woman with a Bjork-Shiley prosthetic mitral valve, presented with pulmonary edema and cardiogenic shock. Doppler echocardiography showed a significant increase of trans-prosthetic gradient due to a thrombotic obstruction. Successful treatment with rt-PA is described. From a subsequent analysis of previous echocardiograms a longstanding asymptomatic thrombus is hypothesised.
authors.affiliation: Servizio di Cardiologia, Ospedale Celesia, Genova, Rivarolo.
authors.forename: D
authors.initials: D
authors.lastname: Astengo
authors.forename: L
authors.initials: L
authors.lastname: Fazzini
authors.forename: R
authors.initials: R
authors.lastname: Piazza
authors.forename: A
authors.initials: A
authors.lastname: Cecchi
mesh_terms: D002908:Chronic Disease; D004452:Echocardiography; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D006350:Heart Valve Prosthesis; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging; D011654:Pulmonary Edema / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D011994:Recombinant Proteins / Q000627:therapeutic use; D012770:Shock, Cardiogenic / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator
vernacular_title: Trombosi di una protesi Bjork-Shiley in sede mitralica: trattamento trombolitico con rt-PA.