Medical treatment of recurrent candidemia in a patient with probable Candida parapsilosis prosthetic valve endocarditis.
Fungal endocarditis is considered an absolute indication for valve replacement surgery. We describe the successful medical treatment of recurrent Candida parapsilosis candidemia with sequential treatment with amphotericin B and fluconazole in a patient with probable prosthetic valve endocarditis. Because of the presumed effectiveness of amphotericin B and fluconazole in the treatment of this patient, medical therapy should be considered as potentially useful in the treatment of recurrent C parapsilosis fungemia or endocarditis or both.
Zahid
M A
MA
Department of Medicine and Microbiology, Veterans Affairs Medical Center, Kansas City, Mo.
Klotz
S A
SA
Hinthorn
D R
DR
D000666:Amphotericin B / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004696:Endocarditis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D015725:Fluconazole / Q000627:therapeutic use; D016469:Fungemia / Q000188:drug therapy* / Q000209:etiology; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D012008:Recurrence
D000666:Amphotericin B; D015725:Fluconazole