title: Radiofrequency catheter ablation as a cure for idiopathic tachycardia of both left and right ventricular origin.
abstract: OBJECTIVE
  The purpose of this study was 1) to investigate the efficacy and safety of radiofrequency energy catheter ablation as curative treatment for idiopathic tachycardia of both left and right ventricular origin, and 2) to compare the usefulness of different methods used to map the site of origin of idiopathic ventricular tachycardia.
  
  
  BACKGROUND
  Percutaneous radiofrequency catheter ablation has been used with dramatic success in the treatment of patients with Wolff-Parkinson-White syndrome, atrioventricular node reentrant tachycardia and bundle branch reentrant tachycardia. Limited data are available on the use of radiofrequency energy catheter ablation as curative treatment for idiopathic tachycardia of both left and right ventricular origin.
  
  
  METHODS
  Twenty-eight consecutive patients (13 to 71 years old) presenting with idiopathic ventricular tachycardia were enrolled in the study. The site of origin of both left and right ventricular tachycardia was mapped using earliest endocardial activation times during tachycardia and by pace mapping. These mapping techniques were compared.
  
  
  RESULTS
  Radiofrequency ablation was successful in all eight patients (100%) with left ventricular tachycardia. Tachycardia recurred in one patient. The ablation procedure was complicated by mild aortic insufficiency in one patient. Right ventricular outflow tract tachycardia was successfully ablated in 17 (85%) of 20 patients. The success rate at follow-up was 85%. In one patient, the ablation procedure was complicated by acute ventricular perforation and death. Pace maps from successful ablation sites were better than pace maps from unsuccessful sites (p < 0.004). Endocardial activation times at successful ablation sites were not different from unsuccessful sites (p < 0.13).
  
  
  CONCLUSIONS
  Radiofrequency catheter ablation is an effective treatment for idiopathic ventricular tachycardia. The site of origin of tachycardia is best identified using pace mapping. Significant complications can occur and should be considered in the risk/benefit analysis for each patient.
authors.affiliation: Department of Medicine, University of California, San Francisco 94143.
authors.forename: D L
authors.initials: DL
authors.lastname: Coggins
authors.forename: R J
authors.initials: RJ
authors.lastname: Lee
authors.forename: J
authors.initials: J
authors.lastname: Sweeney
authors.forename: W W
authors.initials: WW
authors.lastname: Chein
authors.forename: G
authors.initials: G
authors.lastname: Van Hare
authors.forename: L
authors.initials: L
authors.lastname: Epstein
authors.forename: R
authors.initials: R
authors.lastname: Gonzalez
authors.forename: J C
authors.initials: JC
authors.lastname: Griffin
authors.forename: M D
authors.initials: MD
authors.lastname: Lesh
authors.forename: M M
authors.initials: MM
authors.lastname: Scheinman
mesh_terms: D000293:Adolescent; D000328:Adult; D002304:Cardiac Pacing, Artificial / Q000706:statistics & numerical data; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D004452:Echocardiography; D004562:Electrocardiography / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D012008:Recurrence; D013610:Tachycardia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D014694:Ventricular Outflow Obstruction / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*