title: Serum inhibits penicillin-induced L-form growth in Staphylococcus aureus: a note of caution on the use of serum in cultivation of bacterial L-forms.
abstract: Heat-inactivated horse serum inhibited penicillin-induced L-form colony formation in Staphylococcus aureus when included in an osmotically stabilized culture medium. Most, perhaps all, L-form colonies that appeared with low frequencies on the serum-supplemented medium were of the penicillin-independent, stable type. This relationship must be taken into account when use of serum is considered for L-form cultivation.
authors.affiliation: Department of Microbiology, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
authors.forename: O
authors.initials: O
authors.lastname: Shimokawa
authors.forename: M
authors.initials: M
authors.lastname: Ikeda
authors.forename: A
authors.initials: A
authors.lastname: Umeda
authors.forename: H
authors.initials: H
authors.lastname: Nakayama
mesh_terms: D001769:Blood; D015169:Colony Count, Microbial; D003470:Culture Media; D007740:L Forms / Q000254:growth & development* / Q000648:ultrastructure; D010406:Penicillins / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development*
chemical_list: D003470:Culture Media; D010406:Penicillins