title: Multiple giant intracranial aneurysms associated with lymphomatoid granulomatosis. A magnetic resonance imaging and angiographic study.
abstract: Lymphomatoid granulomatosis is an uncommon lymphoproliferative disorder that frequently has central nervous system manifestations. Lymphomatoid granulomatosis has clinical features similar to both vasculitis and lymphoma. The pathological hallmarks of this disease include necrotic angiocentric and angiodestructive infiltrations of premalignant or malignant lymphoid cells. There are, to the authors' knowledge, only a few magnetic resonance imaging reports and no magnetic resonance angiographic reports of this disorder. Presented here is a case of lymphomatoid granulomatosis producing multiple giant fusiform and saccular aneurysms throughout the major intracerebral arteries, along with patterns of vascular beading typically seen with vasculitis demonstrated by magnetic resonance angiography.
authors.affiliation: Lucy Dent Neuroimaging Center, State University of New York at Buffalo Millard Fillmore Hospital.
authors.forename: P M
authors.initials: PM
authors.lastname: Capone
authors.forename: L L
authors.initials: LL
authors.lastname: Mechtler
authors.forename: V E
authors.initials: VE
authors.lastname: Bates
authors.forename: A
authors.initials: A
authors.lastname: Kanna
authors.forename: P R
authors.initials: PR
authors.lastname: Kinkel
mesh_terms: D000293:Adolescent; D002493:Central Nervous System Diseases / Q000150:complications*; D002533:Cerebral Angiography; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000175:diagnosis*; D008230:Lymphomatoid Granulomatosis / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male