title: [Signal characteristics of x-ray contrast media and their interaction with gadolinium-DTPA in MRT].
abstract: T1 and T2 weighted signals derived from various radiological contrast media were studied during MRT spin-echo sequences. In addition, the interaction between radiological contrast media and Gadolinium-DTPA concerning T1 signals was evaluated. Ionic (ioxitalaminic acid) and non-ionic radiological contrast media (Iopromid, Iotrolan) were used in diagnostic concentrations. Measurements were carried out with a superconductive magnet of 1.5 Tesla. Radiological contrast media produced significantly higher signals than a physiological sodium chloride solution in T1-weighted spin-echo sequences. Even small amounts (15% of total volume) of radiological contrast media during T1-weighted spin-echo sequences led to a significant reduction (about 25%) of the signal intensity of a 2 mM Gadolinium-DTPA solution. This may lead to diagnostic problems, as was shown in a series of 25 MR arthrograms of the shoulder. It is recommended than an interval of at least 6 hours should elapse between the use of a radiological contrast medium and an MRT examination.
authors.affiliation: Abteilung Röntgendiagnostik I, Georg-August-Universität Göttingen.
authors.forename: L
authors.initials: L
authors.lastname: Kopka
authors.forename: M
authors.initials: M
authors.lastname: Funke
authors.forename: U
authors.initials: U
authors.lastname: Fischer
authors.forename: R
authors.initials: R
authors.lastname: Vosshenrich
authors.forename: M
authors.initials: M
authors.lastname: Schröder
authors.forename: E
authors.initials: E
authors.lastname: Grabbe
mesh_terms: D003287:Contrast Media; D004347:Drug Interactions; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D011859:Radiography
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
vernacular_title: Signalverhalten von verschiedenen Röntgenkontrastmitteln sowie deren Wechselwirkung mit Gadolinium-DTPA in der MRT.