Expression of estrogen receptors and estrogen-induced proteins in tumors of "hormone non-dependent tissues".
Estrogen receptors (ER), progesterone receptors (PR) and some other estrogen-induced proteins (EIP) were found in the cells of salivary gland carcinomas, thyroid carcinomas, in gliomas and in various farther neoplasms as well as in some normal tissues. The positivity was demonstrated in both females and males. The results indicate that steroid hormones and their receptors could play, both in normal and tumorous tissues, more important biological role than expected so far.
Kolár
Z
Z
Department of Pathology, Medical Faculty, Palacký University, Olomouc, Czech Republic.
Kod'ousek
R
R
Ehrmann
J
J
Macák
J
J
Stárek
I
I
Kucera
J
J
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology; D005260:Female; D055551:HSP27 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D006801:Humans; D008297:Male; D008875:Middle Aged; D018832:Molecular Chaperones; D009124:Muscle Proteins / Q000032:analysis*; D009363:Neoplasm Proteins / Q000032:analysis; D009369:Neoplasms / Q000737:chemistry* / Q000473:pathology; D011506:Proteins; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis; D012468:Salivary Gland Neoplasms / Q000737:chemistry / Q000473:pathology; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000473:pathology
D055551:HSP27 Heat-Shock Proteins; C057725:HSPB1 protein, human; D006360:Heat-Shock Proteins; D018832:Molecular Chaperones; D009124:Muscle Proteins; D009363:Neoplasm Proteins; D011506:Proteins; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone