[Crystal morphological and habit investigations of crystalline drugs. III. Sulfamethizole, levodopa and phenobarbital].
Crystal morphology and habit analyses necessary for a pharmaceutical technique have been studied by a polarizing microscope for tiny crystals of sulfamethizole, levodopa and phenobarbital listed in the Japanese Pharmacopoeia XII. Measurement of key refractive indices by an immersion method has been tried semiautomatically using photographs and the kit of immersion oils produced at 0.005 intervals, and a decision of an orientation of the section has been also carried by conoscope using photos. From the orthographic projections produced by the habit analysis of the colored photo as mentioned in the previous reports morphological and optical properties were clarified.
Watanabe
A
A
Kenbikogaku-kenkyusho, Ltd., Ashiya-shi, Japan.
Ohnuma
N
N
D003460:Crystallization; D007980:Levodopa / Q000737:chemistry*; D008859:Microscopy, Polarization; D010634:Phenobarbital / Q000737:chemistry*; D012031:Refractometry; D013419:Sulfamethizole / Q000737:chemistry*
D013419:Sulfamethizole; D007980:Levodopa; D010634:Phenobarbital