title: Adrenocortical carcinoma in a 12-year-old mare.
abstract: A 12-year-old Dutch warmblood mare was examined because it had suffered colic intermittently for a few years and had lost weight in the previous two months. Palpation per rectum revealed a large firm mass in the left sublumbar region; the mass was classified post mortem as an adrenocortical carcinoma. The basal plasma cortisol concentration (at 10.00) of the mare was 94 nmol/litre, within the normal range. As in another case of adrenocortical neoplasm, a functional tumour could not be demonstrated. Only one of the 21 horses with a neoplasm of the pituitary-adrenocortical axis examined by the authors, had the tumour in the adrenal gland.
authors.affiliation: Department of Large Animal Medicine and Nutrition, Veterinary Faculty, Utrecht University, The Netherlands.
authors.forename: J H
authors.initials: JH
authors.lastname: van der Kolk
authors.forename: M H
authors.initials: MH
authors.lastname: Mars
authors.forename: I
authors.initials: I
authors.lastname: van der Gaag
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D002277:Carcinoma / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D003085:Colic / Q000150:complications / Q000662:veterinary; D005260:Female; D006734:Horse Diseases / Q000097:blood / Q000473:pathology*; D006736:Horses; D006854:Hydrocortisone / Q000097:blood; D009426:Netherlands; D015431:Weight Loss
chemical_list: D006854:Hydrocortisone