Antioxidant action of dietary restriction in the aging process.
Dietary restriction is widely recognized to be the most effective means of intervening in the aging process in laboratory animals. Recent studies have produced substantial evidence that indicates this nutritional manipulation can modulate many aspects of free radical metabolism, including free radical generation, lipid peroxidation, DNA damage and cytosolic defense systems. Some of our laboratory's recent work is summarized in this presentation.
Yu
B P
BP
University of Texas Health Science Center at San Antonio 78284.
D000375:Aging / Q000378:metabolism*; D000818:Animals; D000975:Antioxidants; D002462:Cell Membrane / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D004032:Diet; D002149:Energy Intake / Q000502:physiology*; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000032:analysis; D008560:Membrane Fluidity; D008861:Microsomes / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D011916:Rats, Inbred F344; D017382:Reactive Oxygen Species
D000975:Antioxidants; D017382:Reactive Oxygen Species; D008315:Malondialdehyde