title: Classification and mechanisms of cerebrovascular disease.
abstract: Infarction remains the cause of stroke in 75 to 80% of patients. The leading cause is embolism from one of several sources, although the source of the particles is often not discovered despite prolonged search. Brain infarction associated with high-grade stenosis or occlusion of major arteries may also be caused by local embolism but in one-third of patients, the process of infarction seems attributable to perfusion failure, with a more leisurely evolution of the syndrome than that typical of embolism. Lacunar disease accounts for roughly 20% of strokes.
authors.affiliation: Neurological Institute of New York, Columbia-Presbyterian Medical Center, New York 10032.
authors.forename: J P
authors.initials: JP
authors.lastname: Mohr
mesh_terms: D002545:Brain Ischemia / Q000209:etiology / Q000503:physiopathology; D002544:Cerebral Infarction / Q000209:etiology / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000145:classification / Q000503:physiopathology*; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000503:physiopathology