title: [Local treatment of otitis media and otitis externa: the role of quinolones].
abstract: Patients suffering from suppurative otitis media and externa, and in whom pseudomonas species are present, were treated twice daily by local instillation of ciprofloxacin 0.2%. Treatment resulted in clinical and bacteriological cure in all 17 patients, including patients resistant to previous therapy, within a mean time of six days. There were no adverse effects except one case of local allergy. Audiograms remained unchanged. Local therapy with ciprofloxacin is a welcome addition but should be reserved for cases resistant to other therapy.
authors.affiliation: Dienst N.K.O., A.Z. Middelheim, Antwerpen.
authors.forename: S
authors.initials: S
authors.lastname: De Schepper
authors.forename: B
authors.initials: B
authors.lastname: Schmelzer
mesh_terms: D001299:Audiometry; D002939:Ciprofloxacin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D010032:Otitis Externa / Q000188:drug therapy* / Q000503:physiopathology; D010035:Otitis Media, Suppurative / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D002939:Ciprofloxacin
vernacular_title: Lokale behandeling van otitis media en otitis externa: rol van de quinolones.