title: Antimicrobial treatment of acute otitis media.
abstract: Episodes of acute otitis media frequently occur in childhood and are attended by significant morbidity, such as hearing loss and possible speech delay. Bacteria play an important etiologic role in the pathogenesis of otitis media; therefore, antimicrobial agents are the cornerstone in the treatment of this disease. Many antimicrobial choices are available for treating children with acute otitis media. To choose an antimicrobial for each patient, consideration must be given to the patient's age, history of otitis media episodes, and responses to previously used antimicrobial drugs, and the regional antimicrobial susceptibility of the otitis media pathogens.
authors.affiliation: Otitis Media Research Center, University of Minnesota School of Medicine, Minneapolis.
authors.forename: D M
authors.initials: DM
authors.lastname: Canafax
authors.forename: G S
authors.initials: GS
authors.lastname: Giebink
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000145:classification / Q000627:therapeutic use*; D002675:Child, Preschool; D004432:Ear, Middle / Q000187:drug effects / Q000382:microbiology; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D001936:Moraxella catarrhalis / Q000187:drug effects / Q000302:isolation & purification; D009177:Mycoplasma pneumoniae / Q000187:drug effects / Q000302:isolation & purification; D010033:Otitis Media / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents