Is Percoll safe for in vivo use?
Fourteen virgin female rabbits were injected with 60% Percoll solution in the right ovary and uterine horn and sperm prepared with Percoll in the left ovary and uterine horn. Histologic examination after 4 weeks showed no inflammatory cell infiltration in either uterine horns or ovaries.
Arora
M
M
King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Carver-Ward
J A
JA
Jaroudi
K A
KA
Sieck
U V
UV
D000818:Animals; D002469:Cell Separation / Q000379:methods; D002499:Centrifugation, Density Gradient / Q000379:methods; D003102:Colloids; D004717:Endometrium / Q000187:drug effects / Q000502:physiology; D005260:Female; D008297:Male; D010053:Ovary / Q000187:drug effects / Q000502:physiology; D011205:Povidone / Q000009:adverse effects* / Q000494:pharmacology / Q000592:standards; D011817:Rabbits; D012662:Semen Preservation; D012822:Silicon Dioxide / Q000009:adverse effects* / Q000494:pharmacology / Q000592:standards; D014599:Uterus / Q000187:drug effects / Q000502:physiology
D003102:Colloids; C016039:Percoll; D012822:Silicon Dioxide; D011205:Povidone