title: Duodenogastric reflux demonstrated by cholescintigraphy in peptic ulcer disease and chronic gastritis.
abstract: Duodenogastric (D-G) reflux is commonly associated with peptic ulcer disease and chronic gastritis. To determine D-G reflux in association with each disease entity, we studied 43 chronic gastritis patients and 21 peptic ulcer patients with cholescintigraphy. Scoring (0 to 3+) was judged by the amount of Tc-99m diethylacetanitanilido-IDA (EHIDA) in the stomach. In the chronic gastritis group, 5, 16, 10, and 12 patients scored 3+, 2+, 1+, and 0, respectively. In the peptic ulcer disease group 6, 2, and 13 patients scored 2+, 1+, and 0, respectively. Thirty-nine of the 64 patients (60.9%) were positive for D-G reflux. D-G reflux occurred in 31 of 43 (72.09%) of chronic gastritis patients and in 8 of 21 (38.1%) patients with peptic ulcer disease. D-G reflux was significantly higher in the chronic gastritis group (P = 0.0009). Chronic gastritis patients were more likely to have more marked D-G reflux than peptic ulcer disease (P = 0.048). The authors conclude that cholescintigraphy is noninvasive and objectively demonstrates D-G reflux in chronic gastritis and peptic ulcer disease and that chronic gastritis is more closely associated with D-G reflux than peptic ulcer disease.
authors.affiliation: Guiyang Medical College Affiliated Hospital, Guiyang, China.
authors.forename: G X
authors.initials: GX
authors.lastname: Wang
authors.forename: W J
authors.initials: WJ
authors.lastname: Shih
authors.forename: P L
authors.initials: PL
authors.lastname: Tang
authors.forename: X H
authors.initials: XH
authors.lastname: Dian
authors.forename: W J
authors.initials: WJ
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002908:Chronic Disease; D004383:Duodenogastric Reflux / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging; D005756:Gastritis / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D007098:Imino Acids; D008297:Male; D008875:Middle Aged; D008892:Milk; D015609:Organotechnetium Compounds; D010437:Peptic Ulcer / Q000150:complications / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid