title: Application of the three-dimensional structures of protein target molecules in structure-based drug design.
authors.affiliation: Department of Structural Biology, Abbott Laboratories, Abbott Park, Illinois 60064.
authors.forename: J
authors.initials: J
authors.lastname: Greer
authors.forename: J W
authors.initials: JW
authors.lastname: Erickson
authors.forename: J J
authors.initials: JJ
authors.lastname: Baldwin
authors.forename: M D
authors.initials: MD
authors.lastname: Varney
mesh_terms: D003460:Crystallization; D015195:Drug Design; D017320:HIV Protease Inhibitors / Q000737:chemistry; D015497:HIV-1 / Q000201:enzymology; D008958:Models, Molecular; D015394:Molecular Structure; D011506:Proteins / Q000737:chemistry*; D013329:Structure-Activity Relationship; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors
chemical_list: D017320:HIV Protease Inhibitors; D011506:Proteins; D013940:Thymidylate Synthase