Malignant lymphoma and dermatitis herpetiformis.
We report 2 cases of dermatitis herpetiformis (DH) with lymphoma: a non-Hodgkin's malignant histiocytic lymphoma and a rare phenotype of Hodgkin's disease. With these 2 cases, 32 cases of DH complicated by lymphoma have now been documented. Reviewing the literature we show that the majority of lymphomas (78.1%) arises from the gastro-intestinal tract and that almost all cases of DH with lymphoma are associated with coeliac disease. The possible preventive role of a gluten-free diet is discussed.
Bose
S K
SK
Department of Dermatology, Hôpital Pasteur, University of Nice, France.
Lacour
J P
JP
Bodokh
I
I
Ortonne
J P
JP
D000328:Adult; D002446:Celiac Disease / Q000150:complications* / Q000178:diet therapy; D003874:Dermatitis Herpetiformis / Q000209:etiology*; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male