Germinoma in siblings: case reports.
We present the first reported cases of germinoma occurring in siblings of different genders. One tumor occurred in the left basal ganglia of a 7-year-old boy and the other in the suprasellar region of his 9-year-old sister. Both tumors were diagnosed as germinoma of two-cell pattern based on light and electron microscopic studies. Possible genetic factors responsible for this phenomenon are discussed.
Aoyama
I
I
Department of Neurosurgery, Saiseikai Nakatsu Hospital, Osaka, Japan.
Kondo
A
A
Ogawa
H
H
Ikai
Y
Y
D000293:Adolescent; D001480:Basal Ganglia Diseases / Q000235:genetics / Q000473:pathology; D001932:Brain Neoplasms / Q000235:genetics* / Q000473:pathology; D002648:Child; D005260:Female; D018237:Germinoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male