Intact text-specific implicit memory in patients with Alzheimer's disease.
The ability of patients with Alzheimer's disease (AD) to acquire and retain text-specific knowledge was investigated in a re-reading study. Patients and normal control Ss read 2 passages 3 times, each as quickly as possible, and answered recognition memory questions after the 3rd reading of each passage. The AD patients had poor explicit memory as evidenced by impaired recognition memory for the passages. In contrast, normal decreases in the times required for successive readings of each passage for AD patients indicated intact implicit memory for the passages. The absence of facilitation across passages indicated that the re-reading effect was text specific, suggesting that AD patients may retain the ability to form certain kinds of implicit new associations. Alternative accounts of the mechanism underlying text-specific priming, and of the nature of intact and impaired implicit memory in AD, are considered.
Monti
L A
LA
Rush Alzheimer's Disease Center, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612-3864.
Gabrieli
J D
JD
Wilson
R S
RS
Reminger
S L
SL
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis / Q000523:psychology*; D000849:Anomia / Q000175:diagnosis / Q000523:psychology; D001245:Association Learning; D001288:Attention; D006801:Humans; D008297:Male; D008570:Memory, Short-Term; D011939:Mental Recall; D008875:Middle Aged; D009483:Neuropsychological Tests; D011932:Reading; D012153:Retention, Psychology