Iodine poisoning secondary to long-term iodinated glycerol therapy.
Iodinated glycerol is used as a mucolytic agent in the treatment of chronic obstructive pulmonary disease. Its efficacy is controversial, and reports of its toxicity are substantial. We report a case of chronic iodine poisoning in a patient with chronic obstructive pulmonary disease following 20 years of iodinated glycerol therapy. Reevaluation of the long-term use of this medication is encouraged. Monitoring long-term recipients of iodinated glycerol therapy for chronic iodine poisoning and drug-induced thyroid abnormalities is recommended.
Geurian
K
K
Department of Medical Education, Saint Margaret Memorial Hospital, Pittsburgh PA.
Branam
C
C
D005100:Expectorants / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005990:Glycerol / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced*; D007455:Iodine / Q000506:poisoning*; D008173:Lung Diseases, Obstructive / Q000188:drug therapy; D008875:Middle Aged; D013960:Thyroid Function Tests
D005100:Expectorants; C015372:iodinated glycerol; D007455:Iodine; D005990:Glycerol