title: Two outbreaks of fluorosis in cattle and sheep.
abstract: Two outbreaks of fluorosis in cattle and sheep were investigated in the Northern Transvaal. The animals exhibited severe dental lesions, lameness and exostoses. Plasma fluoride concentrations were high and there was an inversion of the albumin/globulin ratio. Alkaline phosphatase activity was elevated. Drinking water from boreholes contained excessive amounts of fluoride and upon irrigation, pastures were also contaminated with fluoride.
authors.affiliation: Department of Pharmacology and Toxicology, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Republic of South Africa.
authors.forename: C J
authors.initials: CJ
authors.lastname: Botha
authors.forename: T W
authors.initials: TW
authors.lastname: Naudé
authors.forename: P P
authors.initials: PP
authors.lastname: Minnaar
authors.forename: S R
authors.initials: SR
authors.lastname: Van Amstel
authors.forename: S D
authors.initials: SD
authors.lastname: Janse van Rensburg
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology*; D005096:Exostoses / Q000662:veterinary; D005260:Female; D005459:Fluorides / Q000032:analysis; D009050:Fluorosis, Dental / Q000209:etiology / Q000662:veterinary*; D008297:Male; D000455:Medicago sativa / Q000737:chemistry; D012756:Sheep; D012757:Sheep Diseases / Q000209:etiology*; D013019:South Africa; D014873:Water Pollutants / Q000032:analysis
chemical_list: D014873:Water Pollutants; D005459:Fluorides