Comparison of inhaled terbutaline administered by either the Turbuhaler dry powder inhaler or a metered-dose inhaler with spacer in preschool children with asthma.
We compared the bronchodilator response of terbutaline delivered either by a dry powder inhaler, the Turbuhaler, or by a metered-dose inhaler attached to a Nebuhaler inhaler in 10 children with stable asthma who were 3 to 6 years of age. The bronchodilator response did not differ between the two inhalational devices. The dry powder inhaler Turbuhaler is a suitable alternative to a metered-dose inhaler in the delivery of terbutaline to preschool children with stable asthma if adequate inhalational technique is used.
Laberge
S
S
Department of Pediatrics, Hôpital Ste-Justine, Université de Montréal, Québec, Canada.
Spier
S
S
Drblik
S P
SP
Turgeon
J P
JP
D000280:Administration, Inhalation; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D004867:Equipment Design; D006801:Humans; D009330:Nebulizers and Vaporizers; D013726:Terbutaline / Q000008:administration & dosage*
D013726:Terbutaline