Periorbital venous vasculitis, intracranial hypertension and empty sella.
Sixteen patients with chronic periorbital venous vasculitis without nerve involvement and 9 patients with active episodic cluster headache were studied as to cerebrospinal fluid (CSF) pressure. Eighty-one percent of the patients with chronic and 33% with episodic symptoms had pathologically increased CSF pressure. Magnetic resonance imaging of the brains in the chronic group showed empty sella in 60%, cerebral atrophy in 21% and white matter lesions with high signal intensity on T2 weighted sequences in 29%. Abnormal obesity was found in 31% of the patients with chronic periorbital venous vasculitis under 60 years of age. Venous vasculitis is suggested as a cause of intracranial hypertension, empty sella, and endocrinologic dysfunctions.
Hannerz
J
J
Department of Neurology, Karolinska Hospital, Stockholm, Sweden.
Greitz
D
D
Ericson
K
K
D000328:Adult; D015170:Cerebrospinal Fluid Pressure; D003027:Cluster Headache / Q000503:physiopathology; D004652:Empty Sella Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000098:blood supply*; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D014680:Veins