title: Granular cell tumor of the pituitary stalk. Case report.
abstract: The case is described of a granular cell tumor of the pituitary stalk in a 40-year-old woman with secondary amenorrhea. A computerized tomography scan showed a large contrast-enhancing mass, and T1-weighted magnetic resonance images demonstrated a tumor isointense to the brain parenchyma with nonhomogeneous enhancement after intravenous administration of gadolinium diethylenetriamine penta-acetic acid. Histopathological examination, especially immunocytochemical and electron microscopic studies, showed elements supporting an astrocytic origin for this type of tumor, a hypothesis advanced by many authors but still controversial.
authors.affiliation: Department of Neurosciences, C.H.U. Bretonneau, Tours, France.
authors.forename: C
authors.initials: C
authors.lastname: Lafitte
authors.forename: B
authors.initials: B
authors.lastname: Aesch
authors.forename: F
authors.initials: F
authors.lastname: Henry-Lebras
authors.forename: F
authors.initials: F
authors.lastname: Fetissof
authors.forename: M
authors.initials: M
authors.lastname: Jan
mesh_terms: D000328:Adult; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D016586:Granular Cell Tumor / Q000175:diagnosis* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008854:Microscopy, Electron; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA