title: Vasovagal syncope with bradycardia during lower body negative pressure in a heart transplant recipient.
abstract: Vasovagal syncope has been ascribed to the vagal excitation and the sympathetic inhibition induced reflexly by mechanical stimulation of receptors in the ventricles. In this case report we describe a vasovagal syncope with bradycardia triggered by a reduction in venous return obtained via mild lower body negative pressure, in a patient with cardiac denervation due to heart transplantation. This suggests that the mechanisms involved in this phenomenon may not exclusively depend on a reflex originating from ventricular receptors. It also suggests that non-neural factors may be involved in the genesis of the bradycardia.
authors.affiliation: Department of Internal Medicine, University of Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Giannattasio
authors.forename: G
authors.initials: G
authors.lastname: Grassi
authors.forename: G
authors.initials: G
authors.lastname: Mancia
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D001919:Bradycardia / Q000503:physiopathology*; D004562:Electrocardiography; D006339:Heart Rate / Q000502:physiology; D016027:Heart Transplantation / Q000502:physiology*; D006801:Humans; D008150:Lower Body Negative Pressure; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow / Q000502:physiology; D013575:Syncope / Q000503:physiopathology*; D014630:Vagus Nerve / Q000503:physiopathology