title: Cytomegalovirus colitis in patients with acquired immunodeficiency syndrome.
abstract: The spectrum of presentation of complications in patients with human immunodeficiency virus (HIV) disease is changing, in line with their improved survival. Infection of the colon with cytomegalovirus (CMV) is now more commonly encountered in clinical practice. We have reviewed the medical records of eleven patients with clinical and pathological evidence of CMV colitis. The clinical presentation, endoscopic and histological findings, and simultaneous infection of other organs with CMV are discussed. Diarrhoea in association with abdominal pain is the most frequent symptom complex in these patients and should raise the clinical index of suspicion for CMV colitis.
authors.affiliation: Department of Medicine, SUNY Health Sciences Center at Stony Brook 11794.
authors.forename: C V
authors.initials: CV
authors.lastname: DeRodriguez
authors.forename: J
authors.initials: J
authors.lastname: Fuhrer
authors.forename: G
authors.initials: G
authors.lastname: Lake-Bakaar
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000473:pathology; D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D003092:Colitis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D003106:Colon / Q000473:pathology; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D003967:Diarrhea / Q000209:etiology*; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012007:Rectum / Q000473:pathology
chemical_list: D015774:Ganciclovir; D000212:Acyclovir