Considerations on the prognostic significance of bone marrow micrometastases in breast cancer.
Research of bone marrow micrometastases in patients with breast cancer was proposed as a prognostic factor in order to detect those patients at high risk for early recurrence. The Authors present a review of current literature and describe the different methods used, with particular regard to monoclonal antibodies. The biological significance and prognostic value of the presence of bone marrow micrometastases in clinically Mo patients with breast cancer are discussed.
Pecorini
F
F
III Clinica Ostetrica e Ginecologica, Policlinico Umberto I Università di Roma La Sapienza.
Veneziano
M
M
Framarino Dei Malatesta
M L
ML
Passarello
A
A
Trapani
E
E
Burgio
V
V
Marzetti
L
L
D001853:Bone Marrow / Q000473:pathology* / Q000648:ultrastructure; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D011379:Prognosis