Bacteriological study of Neisseria strains isolated in Romania 1971-1992.
1496 Neisseria strains isolated from patients and carriers from 24 counties in Romania and Bucharest in 1971-1992 were studied. Serogroup A identified in 84.5% in 1987 shows a remarkable decrease in pre- and post-epidemic periods when serogroups B and C reach rates varying from 0 to 66.6% in 1975 for B and 38.8% in 1974 for C. Non-groupable strains were more frequently isolated in inter-epidemic periods, especially in carriers. Sensitivity to antibiotics of the meningococcal strains revealed a law rate of resistant strains, the most active antibiotics in decreasing order being: penicillin, chloramphenicol, tetracycline, ampicillin, rifampicin and erythromycin. Serogroup A was the most resistant to sulfamides as compared to the other serogroups, its resistance rate rising from 18.1% strains resistant to sulfathiazole in 1980-1985 to 60.7% in 1987 and to 83.3% in 1988.
Leveneţ
I
I
Cantacuzino Institute, Bucharest, Romania.
Paşolescu
O
O
Mihalcu
F
F
Gulan
L
L
Dorobăţ
O
O
Lucinescu
S
S
Iacob
A
A
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002353:Carrier State / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006801:Humans; D008585:Meningitis, Meningococcal / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D009343:Neisseria / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D009345:Neisseria meningitidis / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification; D012383:Romania; D012703:Serotyping; D013449:Sulfonamides / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D013449:Sulfonamides