title: Single daily monitoring of periovulatory estradiol, progesterone, and luteinizing sera hormone levels in natural cycles useful for timing intrauterine insemination.
abstract: Single daily periovulatory serum levels of luteinizing hormone (LH), estradiol (E2), and progesterone (P) may be useful to predict the time of ovulation, since serum P is known to rise to 1000 pg/mL about 24 h after the LH surge. Intrauterine insemination (IUI) was performed based on the serum P level at the time of the LH surge; if sera P measures < 1000 pg/mL, then IUI is performed 36-40 h later; but if P is > or = 1000 pg/mL, IUI is performed 12-20 h later. The relationship of sera LH, E2, and P levels and follicular diameter were evaluated at the time of the LH surge and the day before in 40 women with cervical factor who conceived following a single IUI. If E2 levels were obtained the day before and the day of the LH surge and measured < 200 or > or = 200 pg/mL, a shorter interval for the IUI was suggested. The 27% pregnancy rate/cycle suggests that measurement of single daily periovulatory hormonal levels are useful for precise timing of IUI.
authors.affiliation: University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden.
authors.forename: J H
authors.initials: JH
authors.lastname: Check
authors.forename: M
authors.initials: M
authors.lastname: Peymer
authors.forename: P
authors.initials: P
authors.lastname: Jairaj
mesh_terms: D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D007315:Insemination, Artificial; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D010060:Ovulation / Q000502:physiology*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood*; D013997:Time Factors
chemical_list: D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone