title: Direct screening of a mitochondrial DNA deletion valuable for Amerindian evolutionary research.
abstract: A rapid, simple restriction isotyping method is described for the direct screening of a previously characterized Amerindian mitochondrial DNA (mtDNA) marker consisting of a 6-bp "Huetar" deletion. In a sample of 31 maternally non-related Chibchan Amerindian Bribri from Costa Rica, this deletion was present in 74%, arguing for the usefulness of this private polymorphism for Amerindian taxonomic research.
authors.affiliation: Sección de Genética Humana, Instituto de Investigaciones en Salud (INISA), Universidad de Costa Rica, San José.
authors.forename: M
authors.initials: M
authors.lastname: Santos
authors.forename: R
authors.initials: R
authors.lastname: Barrantes
mesh_terms: D001483:Base Sequence; D005075:Biological Evolution; D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D007197:Indians, Central American / Q000235:genetics*; D008969:Molecular Sequence Data; D017384:Sequence Deletion
chemical_list: D004272:DNA, Mitochondrial