Tris(hydroxymethyl)aminomethane (C4H11NO3) induced a ripple phase in supported unilamellar phospholipid bilayers.
A commonly used buffer compound, tris(hydroxymethyl)aminomethane (C4H11NO3), was found to induce a ripple phase in supported unilamellar phospholipid bilayers at room temperature. The ripple structure showed various types of domains that could extend to several micrometers in length with many well-defined bendings of either 120 degrees or 60 degrees. Two different periodic ripples were found to coexist in 1,2-dipentadecanoyl-sn-glycero-3-phosphatidylcholine bilayers. Some intermediate states during the transition to the ripple phase were also observed.
Mou
J
J
Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville 22908.
Yang
J
J
Shao
Z
Z
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D008051:Lipid Bilayers; D008853:Microscopy; D010713:Phosphatidylcholines / Q000737:chemistry; D010743:Phospholipids / Q000737:chemistry*; D013696:Temperature; D014325:Tromethamine / Q000494:pharmacology*
D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D010743:Phospholipids; D014325:Tromethamine; C037108:1,2-pentadecanoylphosphatidylcholine