title: Rolling review: gastrointestinal malignancy.
abstract: The chemotherapy of gastrointestinal malignancies remain mostly investigational, although several adjuvant protocols in colorectal cancer and anal cancer are beginning to be accepted as standards against which newer regimens are to be compared. Chemotherapy regimens are best understood and appreciated with a basic understanding of cancer biology, tumour cell kinetics, and drug toxicities. An appreciation of chemotherapy-induced toxicity and an awareness of their management will help the gastroenterologist be an active participant in the multidisciplinary team caring for the patient with gastrointestinal malignancies.
authors.affiliation: Department of Veterans Affairs Medical Center, Dallas, TX 75216.
authors.forename: G D
authors.initials: GD
authors.lastname: Luk
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002453:Cell Cycle / Q000187:drug effects; D017024:Chemotherapy, Adjuvant; D004067:Digestive System Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans
chemical_list: D000970:Antineoplastic Agents