title: Assessment of regional left ventricular long-axis motion with MR velocity mapping in healthy subjects.
abstract: The pattern of left ventricular long-axis motion during early diastole was assessed with magnetic resonance (MR) velocity mapping in 31 healthy volunteers. Regional long-axis velocity varied with time and position around the ventricle. During systole, the base descended toward the apex. The greatest magnitude of long-axis velocity occurred during early diastole. The lateral wall had the highest velocity (140 mm/sec +/- 40 [mean +/- standard deviation]); the anterior and inferior walls had lower velocities (96 mm/sec +/- 27 and 92 mm/sec +/- 34, respectively). The inferoseptal area consistently had the lowest velocities (87 mm/sec +/- 40). Absolute values of peak early-diastolic velocity declined with age (r = -.64, P < .001). Peak early-diastolic velocity was not dependent on heart rate (r = .014, P = .94). Regional variations in left ventricular wall motion were seen. MR velocity mapping is a useful technique for assessing regional left ventricular long-axis heart function.
authors.affiliation: Royal Brompton National Heart and Lung Hospital, London, England.
authors.forename: S P
authors.initials: SP
authors.lastname: Karwatowski
authors.forename: R
authors.initials: R
authors.lastname: Mohiaddin
authors.forename: G Z
authors.initials: GZ
authors.lastname: Yang
authors.forename: D N
authors.initials: DN
authors.lastname: Firmin
authors.forename: M S
authors.initials: MS
authors.lastname: Sutton
authors.forename: S R
authors.initials: SR
authors.lastname: Underwood
authors.forename: D B
authors.initials: DB
authors.lastname: Longmore
mesh_terms: D000328:Adult; D000368:Aged; D003971:Diastole / Q000502:physiology*; D005069:Evaluation Studies as Topic; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009040:Motion Pictures; D009200:Myocardial Contraction / Q000502:physiology; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*