Direct screening of a mitochondrial DNA deletion valuable for Amerindian evolutionary research.
A rapid, simple restriction isotyping method is described for the direct screening of a previously characterized Amerindian mitochondrial DNA (mtDNA) marker consisting of a 6-bp "Huetar" deletion. In a sample of 31 maternally non-related Chibchan Amerindian Bribri from Costa Rica, this deletion was present in 74%, arguing for the usefulness of this private polymorphism for Amerindian taxonomic research.
Santos
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Sección de Genética Humana, Instituto de Investigaciones en Salud (INISA), Universidad de Costa Rica, San José.
Barrantes
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D001483:Base Sequence; D005075:Biological Evolution; D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D007197:Indians, Central American / Q000235:genetics*; D008969:Molecular Sequence Data; D017384:Sequence Deletion
D004272:DNA, Mitochondrial