title: Volumetric analysis of epilepsy surgery resections using high resolution magnetic imaging: technical report.
abstract: A method is described for accurately measuring the volume and site of epilepsy surgery resections utilizing magnetic resonance imaging. Accuracy has been assessed using post-mortem studies, and both the intra- and interobserver variability is consistently less than 5%. The technique has so far been applied to 25 patients following a variety of operations for medically intractable epilepsy. It provides the crucially accurate baseline required for meaningful follow-up outcome studies of epilepsy surgery. Consequently, it should allow the development of more precise prognostic indices for such operations.
authors.affiliation: Department of Neurological Surgery, Institute of Neurology, London, UK.
authors.forename: N D
authors.initials: ND
authors.lastname: Kitchen
authors.forename: D G
authors.initials: DG
authors.lastname: Thomas
authors.forename: S D
authors.initials: SD
authors.lastname: Shorvon
authors.forename: D R
authors.initials: DR
authors.lastname: Fish
authors.forename: J M
authors.initials: JM
authors.lastname: Stevens
mesh_terms: D001921:Brain / Q000473:pathology* / Q000601:surgery; D004827:Epilepsy / Q000175:diagnosis / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D015588:Observer Variation; D011237:Predictive Value of Tests; D011379:Prognosis; D012016:Reference Values