title: The yeast actin cytoskeleton.
abstract: Budding and fission yeast present significant advantages for studies of the actin cytoskeleton. The application of classical and molecular genetic techniques provides a facile route for the analysis of structure/function relationships, for the isolation of novel proteins involved in cytoskeletal function, and for deciphering the signals that regulate actin assembly in vivo. This review focuses on the budding yeast Saccharomyces cerevisiae and also identifies some recent advances from studies on the fission yeast Schizosaccharomyces pombe, for which studies on the actin cytoskeleton are still in their infancy.
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley 94720.
authors.forename: M D
authors.initials: MD
authors.lastname: Welch
authors.forename: D A
authors.initials: DA
authors.lastname: Holtzman
authors.forename: D G
authors.initials: DG
authors.lastname: Drubin
mesh_terms: D000199:Actins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D002453:Cell Cycle; D003599:Cytoskeleton / Q000502:physiology* / Q000648:ultrastructure; D005800:Genes, Fungal; D008840:Microfilament Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure; D012568:Schizosaccharomyces / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction
chemical_list: D000199:Actins; D008840:Microfilament Proteins