Neonatal intracranial lesions following placental abruption.
A case-controlled study of the cerebral ultrasound appearances of neonates following placental abruption was undertaken. Twenty-nine index subjects (median gestation 29 weeks) were identified over a 2-year period with gestation- and sex-matched controls. Placental abruption was associated with a four-fold increased incidence of periventricular leukomalacia and extensive periventricular haemorrhage, without increased mortality. Ten infants (34%) developed cystic periventricular leukomalacia following placental abruption, compared with three (10%) in the control group. Intraventricular haemorrhage (excluding subependymal haemorrhage) and haemorrhage into the brain parenchyma occurred in 21 (72%) infants in the abruption group, compared with 14 (48%) in the control group (P < 0.05).
Gibbs
J M
JM
Regional Neonatal Intensive Care Unit, Liverpool Maternity Hospital, UK.
Weindling
A M
AM
D000037:Abruptio Placentae / Q000150:complications*; D016022:Case-Control Studies; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*; D004453:Echoencephalography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging / Q000209:etiology*; D011247:Pregnancy; D012189:Retrospective Studies