title: Delayed-onset focal dystonia after diffuse cerebral hypoxia--two case reports.
abstract: The delayed-onset focal dystonia is a rare sequela of cerebrovascular disease or diffuse cerebral hypoxic damage. The responsible lesion sites for the dystonia are variable and the pathogenesis is uncertain. We describe two children with delayed-onset focal dystonia as a complication of perinatal anoxia. The intervals between hypoxic insult and onset of dystonia were 6 years in one and 3 in the other cases. Our patients did not have a focal lesion; one had scattered white matter lesion and the other had a diffuse frontoparietal atrophy. Delayed-onset dystonia after perinatal anoxia can be also caused by non-focal lesion such as diffuse frontoparietal atrophy or cerebral white matter lesion with long interval delay.
authors.affiliation: Department of Neurology, Youngdong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Y C
authors.initials: YC
authors.lastname: Choi
authors.forename: M S
authors.initials: MS
authors.lastname: Lee
authors.forename: I S
authors.initials: IS
authors.lastname: Choi
mesh_terms: D002648:Child; D004421:Dystonia / Q000209:etiology*; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications*; D008297:Male; D013997:Time Factors