[DNA hyperproduction in the blood plasma of animals with experimental diabetes and its compensation using the transplantation of insulin-producing tissue into the anterior chamber].
Comparative analysis of serum DNA content in healthy rats, rats with experimental alloxan diabetes, and the rats with the diabetes compensated by transplantation of the embryonal pancreas into the anterior chamber of the eye. In the course of diabetes the concentration of free-circulating serum DNA reliably increase 10-12 times, and the compensation of the diabetes returns it to the norm. The revealed relationship may be used for diagnostics of initiation and full compensation of the insulin-dependent diabetes.
Trubetskaia
O E
OE
Kulikov
A V
AV
Afanas'eva
G V
GV
Reznikov
K Iu
KIu
D000818:Animals; D000867:Anterior Chamber; D004247:DNA / Q000097:blood*; D003921:Diabetes Mellitus, Experimental / Q000097:blood* / Q000601:surgery*; D004587:Electrophoresis, Agar Gel; D016332:Fetal Tissue Transplantation; D016381:Islets of Langerhans Transplantation; D051381:Rats; D017208:Rats, Wistar; D016042:Transplantation, Heterotopic; D014184:Transplantation, Homologous
D004247:DNA
Giperproduktsiia DNK v plazme krovi u zhivotnykh s éksperimental'nym diabetom i ee kompensatsiia s pomoshch'iu transplantatsii insulinprodutsiruiushcheĭ tkani v peredniuiu kameru glaza.