[Detection of antibodies to sulpholipid IV from mycobacterium tuberculosis in pulmonary tuberculosis patients].
Serum IgG and IgM antibodies against a novel 2,3-diacyl-trehalose-2'-sulphate (SLIV) antigen using ELISA were determined in control (n = 112) and in pulmonary tuberculosis (n = 120) patients. The specificity and sensitivity of SLIV-IgG-ELISA were 96% and 52%, respectively. Those of SLIV-IgM-ELISA were 95% and 33%, respectively. Compared with PPD-IgG-ELISA, SLIV-IgG-ELISA showed that the specificity was about the same but the sensitivity was higher.
Hou
W
W
Institute of Dermatology CAMS, Nanjing.
Wu
Q X
QX
Zhang
P Z
PZ
D000907:Antibodies, Bacterial / Q000097:blood*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D009169:Mycobacterium tuberculosis / Q000276:immunology* / Q000302:isolation & purification; D012680:Sensitivity and Specificity; D014199:Trehalose / Q000031:analogs & derivatives* / Q000276:immunology / Q000302:isolation & purification; D014397:Tuberculosis, Pulmonary / Q000276:immunology* / Q000382:microbiology
C087075:2,3-diacyltrehalose-2'-sulfate; D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014199:Trehalose