title: Lhermitte-Duclos disease. A case report.
abstract: We report one case of histologically proved Lhermitte-Duclos disease. Suspected on the basis of CT and angiography, the pre-operative diagnosis has been confirmed by the characteristic features of the lesion on MRI: a unilateral posterior fossa mass, hyperintense on proton density and T2-weighted images, hypointense on T1-weighted images, non enhancing after Gd administration. The gyral pattern was preserved, but a specific thickening of cerebellar folia was demonstrated. Despite a good post-operative short term prognosis, recurrence may occur. With a better depiction of lesion limits, MRI could improve the surgical approach and reduce the risk of subtotal excision.
authors.affiliation: Hôpital de Jolimont, Service de Radiologie, La Louvière, Belgique.
authors.forename: P
authors.initials: P
authors.lastname: Hulcelle
authors.forename: G
authors.initials: G
authors.lastname: Dooms
authors.forename: J
authors.initials: J
authors.lastname: Vermonden
mesh_terms: D000328:Adult; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media; D005682:Gadolinium; D019786:Gadolinium DTPA; D005729:Ganglioneuroma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA