title: [Adult age phenylketonuria with extrapyramidal syndrome: therapeutic management].
abstract: A young male with phenylketonuria diagnosed in his 9-th month of life is presented. At the age of 20 years signs of central nervous system involvement became more pronounced, with extrapyramidal syndrome and with simultaneous very striking increase of phenylalanine level. The neurological signs were reduced after administration of Levodopa (Nakom) and return to more strict diet and Lofenalac.
authors.affiliation: II Katedry i Kliniki Neurologii Sl. AM, Zabrzu.
authors.forename: K
authors.initials: K
authors.lastname: Pierzchała
authors.forename: D
authors.initials: D
authors.lastname: Rościszewska
authors.forename: J
authors.initials: J
authors.lastname: Kwieciński
mesh_terms: D000328:Adult; D017668:Age of Onset; D000978:Antiparkinson Agents / Q000494:pharmacology / Q000627:therapeutic use; D001480:Basal Ganglia Diseases / Q000150:complications / Q000503:physiopathology*; D002230:Carbidopa / Q000494:pharmacology / Q000627:therapeutic use; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D004338:Drug Combinations; D006801:Humans; D007980:Levodopa / Q000494:pharmacology / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D009069:Movement Disorders / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D010649:Phenylalanine / Q000097:blood / Q000378:metabolism; D010661:Phenylketonurias / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D011581:Psychological Tests; D014057:Tomography, X-Ray Computed
chemical_list: D000978:Antiparkinson Agents; D004338:Drug Combinations; C009265:carbidopa, levodopa drug combination; D007980:Levodopa; D010649:Phenylalanine; D002230:Carbidopa
vernacular_title: Fenyloketonuria wieku dojrzałego z zespołem pozapiramidowym--postepowanie terapeutyczne.