[Prokinetic activity and antral inflammation. Usefulness of cisapride combined with H2 antagonists in gastritis].
In order to evaluate the symptomatic efficacy of cisapride on motility disorders often associated with mild inflammatory changes of the upper gastrointestinal tract, the authors carried out a comparison between two groups of patients (15 patients in each group, 10 males and 5 females) with histologic antral gastritis, treated respectively with famotidine 40 mg/day per os plus cisapride 10 mg ter/die per os, and famotidine alone. While the endoscopic evaluation performed four weeks later did not show a significant difference between the two groups, both macroscopically and microscopically, cisapride was able to ameliorate all those symptoms presumably provoked by delayed gastric emptying.
Dallera
F
F
Servizio di Gastroenterologia ed Endoscopia Digestiva, O.M., Ospedale di Lodi.
Scanzi
G
G
Gendarini
A
A
D000897:Anti-Ulcer Agents / Q000494:pharmacology / Q000627:therapeutic use*; D020117:Cisapride; D004359:Drug Therapy, Combination; D015738:Famotidine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005756:Gastritis / Q000188:drug therapy* / Q000503:physiopathology; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D008297:Male; D010880:Piperidines / Q000494:pharmacology / Q000627:therapeutic use*; D011706:Pyloric Antrum / Q000503:physiopathology
D000897:Anti-Ulcer Agents; D010880:Piperidines; D015738:Famotidine; D020117:Cisapride
Attività procinetica e flogosi antrale. Utilità della cisapride associata ad H2 antagonista nella gastrite.