Binding and internalization of microorganisms by integrin receptors.
Many microbial pathogens bind host-cell integrin receptors. These interactions are promoted either by a host protein binding the microorganism or by a surface-localized ligand encoded by the pathogen. Attachment facilitates extracellular adhesion of the microorganism or internalization by the host cell.
Isberg
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Howard Hughes Medical Institute, Boston, MA.
Tran Van Nhieu
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D000595:Amino Acid Sequence; D000818:Animals; D001419:Bacteria / Q000378:metabolism; D056890:Eukaryota / Q000378:metabolism; D006801:Humans; D016023:Integrins / Q000378:metabolism*; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D014780:Viruses / Q000378:metabolism
D016023:Integrins; D009842:Oligopeptides; D010455:Peptides; C047981:arginyl-glycyl-aspartic acid