title: The relationship between the sialic acid concentrations in the serum and whole saliva in rats with naturally occurring gingivitis.
abstract: Pocket probing depth was correlated with the amount of salivary sialic acid in pilocarpine-stimulated saliva in ODU plaque-susceptible rats (ODUS/Odu) (r = 0.657, P < 0.01), but not with the content of serum sialic acid. There was no difference in the amount of serum sialic acid content between ODUS/Odu and plaque-resistant rats. These results suggest that the amount of sialic acid in the saliva can be a useful index of the severity of periodontal disease.
authors.affiliation: Department of Pharmacology, Osaka Dental University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Shinohara
authors.forename: K
authors.initials: K
authors.lastname: Ohura
authors.forename: K
authors.initials: K
authors.lastname: Ogata
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: T
authors.initials: T
authors.lastname: Miyata
authors.forename: M
authors.initials: M
authors.lastname: Yoshioka
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis; D005891:Gingivitis / Q000378:metabolism*; D008297:Male; D019158:N-Acetylneuraminic Acid; D051381:Rats; D011921:Rats, Inbred WKY; D012463:Saliva / Q000737:chemistry*; D012794:Sialic Acids / Q000032:analysis* / Q000097:blood
chemical_list: D015415:Biomarkers; D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid