[Lyme disease in China and its ocular manifestations].
The authors report 30 chinese patients of ocular Lyme borreliosis, which is a tick-borne spirochaetal disease involving multiple organ systems. The ocular manifestations begin as conjunctivitis, and then as uveitis, choroidoretinitis, keratitis and vitritis. Diagnosis is based on case history and clinical and laboratory findings. Early cases may be cured by oral antibiotics while intravenous drip of large dosage is needed for advanced cases, with a relapsing rate of 16%. Prolonged systemic corticosteroids may predispose the patient to antibiotic failure; however, topical corticosteroids in combination with antibiotics may minimize ocular inflammation and complications.
Liu
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Department of Ophthalmology, Chinese Navy General Hospital, Beijing.
D000293:Adolescent; D000328:Adult; D000368:Aged; D015748:Borrelia burgdorferi Group / Q000302:isolation & purification*; D002443:Ceftriaxone / Q000627:therapeutic use; D002648:Child; D002825:Chorioretinitis / Q000188:drug therapy / Q000382:microbiology; D003234:Conjunctivitis, Bacterial / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D010406:Penicillins / Q000627:therapeutic use; D014605:Uveitis / Q000188:drug therapy / Q000382:microbiology*
D010406:Penicillins; D002443:Ceftriaxone