Increased thrombogenicity after polymer coating: experiences with the first version of a new woven Dacron graft for aortic reconstruction.
OBJECTIVE
To assess the initial results of insertion of a new woven Dacron graft coated with a polymer for occlusive and aneurysmal aortoiliac disease.


METHODS
Open study.


METHODS
Four Swedish vascular surgical units.


METHODS
28 patients who required aortoiliac or aortofemoral reconstruction between September 1988 and June 1989.


METHODS
Incidence of, and time to, occlusion; type of intervention; whether the graft needed to be replaced; and mortality.


RESULTS
Two patients died in the postoperative period, and five during follow-up, giving an overall mortality of 25%. None of the tube grafts occluded but 17 of 24 bifurcation grafts did (71%), the median time to occlusion being 126 days (range 10-820). Our results have led to this graft being removed from the market while modifications are made in the process of impregnation of polymer.


CONCLUSIONS
Strict protocols for the assessment of new graft materials should be introduced and enforced.
Björck
C G
CG
Department of Surgery, County Hospital of Falun, Sweden.
Bergqvist
D
D
Glimåker
H
H
Hallstensson
S
S
Qvarfordt
P
P
Troëng
T
T
D000368:Aged; D000818:Animals; D001011:Aorta / Q000601:surgery*; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery; D001018:Aortic Diseases / Q000601:surgery; D001157:Arterial Occlusive Diseases / Q000601:surgery; D001807:Blood Vessel Prosthesis / Q000379:methods* / Q000401:mortality; D005260:Female; D006083:Graft Occlusion, Vascular / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D011108:Polymers; D012086:Reoperation
D011093:Polyethylene Terephthalates; D011108:Polymers