title: 167-A, a new antibiotic produced by a mutant of an inactive wild strain of Amycolata autotrophica.
abstract: Two related antibiotics, 167-A and 167-B, were isolated from the fermentation broth of a mutant of an inactive wild strain of Amycolata autotrophica. Antibiotic 167-B was found to be cervinomycin A2; antibiotic 167-A is a new representative of the same group and has the structure of 18-O-demethyl cervinomycin A2.
authors.affiliation: Institute of New Antibiotics, Moscow, Russia.
authors.forename: N D
authors.initials: ND
authors.lastname: Malkina
authors.forename: Y V
authors.initials: YV
authors.lastname: Dudnik
authors.forename: L N
authors.initials: LN
authors.lastname: Lysenkova
authors.forename: E I
authors.initials: EI
authors.lastname: Lazhko
authors.forename: O A
authors.initials: OA
authors.lastname: Galatenko
authors.forename: G S
authors.initials: GS
authors.lastname: Katrukha
mesh_terms: D000192:Actinomycetales / Q000145:classification / Q000378:metabolism*; D018943:Anthracyclines; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005285:Fermentation; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D016296:Mutagenesis
chemical_list: C087128:18-O-demethylcervinomycin A2; D018943:Anthracyclines; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; C035628:cervinomycin A2