title: A comparison of in vitro fertilization results after embryo transfer after 2, 3, and 4 days of embryo culture.
abstract: Embryo transfer results after a 2 to 4 day period of embryo culture were compared. Two thousand two hundred ninety-seven ETs, performed in 1991 and 1992, were analyzed. Ongoing pregnancy rates after 2, 3, or 4 days of embryo culture were 23.3%, 21.9%, and 26.4%, respectively. Multiple pregnancy rates were 36.2%, 38.8%, and 32.6% per ongoing pregnancy for the three groups, respectively. The implantation rate of 73 cavitating morulae on day 4 was surprisingly high (41%) compared with that of other developmental stages. Transfer after 4 days of culture gives the ability to recognize embryos with a very high implantation potential.
authors.affiliation: Department of Obstetrics and Gynaecologie, Academic Hospital Rotterdam, Dijkzigt, The Netherlands.
authors.forename: G J
authors.initials: GJ
authors.lastname: Huisman
authors.forename: A T
authors.initials: AT
authors.lastname: Alberda
authors.forename: R A
authors.initials: RA
authors.lastname: Leerentveld
authors.forename: A
authors.initials: A
authors.lastname: Verhoeff
authors.forename: G H
authors.initials: GH
authors.lastname: Zeilmaker
mesh_terms: D002478:Cells, Cultured; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000166:cytology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011446:Prospective Studies; D013997:Time Factors