Cytomegalovirus disease in a renal transplant recipient manifesting with pericarditis.
A 12-year-old uraemic patient who had received a renal allograft from a donor of unknown cytomegalovirus (CMV) serology was evaluated for subfebrile fever and pericardial effusion. Viral DNA was detected with PCR. The patient responded very well to Ganciclovir therapy. This patient highlights the importance of donor serology and the need for careful evaluation of even minor signs and symptoms of CMV disease.
Saatci
U
U
Department of Paediatric Nephrology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
Ozen
S
S
Ceyhan
M
M
Secmeer
G
G
D002648:Child; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections; D004279:DNA, Viral / Q000032:analysis; D005334:Fever / Q000382:microbiology*; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D010490:Pericardial Effusion / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D010493:Pericarditis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D014511:Uremia / Q000601:surgery
D004279:DNA, Viral; D015774:Ganciclovir