title: Angiotensinamide in the treatment of probable anaphylaxis to succinylated gelatin (Gelofusine).
abstract: A patient undergoing anaesthesia for coronary artery bypass surgery developed a probable anaphylactic reaction to succinylated gelatin (Gelofusine). The principal feature of the reaction was one of cardiovascular depression. An infusion of the angiotensin analogue, angiotensinamide was successful in the treatment of the reaction and allowed completion of the surgery.
authors.affiliation: Department of Anaesthetics, Royal Infirmary of Edinburgh.
authors.forename: R P
authors.initials: RP
authors.lastname: McKinnon
authors.forename: C J
authors.initials: CJ
authors.lastname: Sinclair
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced / Q000188:drug therapy*; D000768:Anesthesia, General; D000802:Angiotensin Amide / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D001026:Coronary Artery Bypass; D005780:Gelatin / Q000009:adverse effects*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008875:Middle Aged; D010952:Plasma Substitutes; D013386:Succinates / Q000009:adverse effects*
chemical_list: D010952:Plasma Substitutes; D013386:Succinates; D007073:Immunoglobulin E; C060085:succinylated gelatin; D000802:Angiotensin Amide; D005780:Gelatin