[Pharmacokinetics and metabolism of synthetic androgen and anabolic hormone].
Esters of 17 beta position of testosterone and nandrolone gradually liberate their free forms into circulation, which are metabolized through usual androgen pathway. 17 beta-hydroxy-17 alpha-methyl compounds, used per os as androgenic and anabolic drugs, show complicated metabolism, including saturation of A ring, degradation of substituted radicals at A ring, hydroxylation at 6 and/or 16, and epimerization at 17. These metabolites are excreted as free or conjugated forms with glucuronidate and sulfate.
Shimazaki
J
J
Department of Urology, School of Medicine, Chiba University.
D045930:Anabolic Agents / Q000378:metabolism / Q000493:pharmacokinetics*; D000818:Animals; D006801:Humans; D045165:Testosterone Congeners / Q000378:metabolism / Q000493:pharmacokinetics*
D045930:Anabolic Agents; D045165:Testosterone Congeners