title: Design and operation of a recombinant mammalian cell manufacturing process for rFVIII.
authors.affiliation: Genetics Institute, Cambridge, MA 01240.
authors.forename: R
authors.initials: R
authors.lastname: Adamson
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000378:metabolism; D016466:CHO Cells; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism; D006224:Cricetinae; D005169:Factor VIII / Q000096:biosynthesis* / Q000302:isolation & purification / Q000378:metabolism; D006801:Humans; D007668:Kidney; D007700:Kinetics; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D011994:Recombinant Proteins / Q000096:biosynthesis* / Q000302:isolation & purification / Q000378:metabolism; D013552:Swine; D013997:Time Factors; D014162:Transfection; D014841:von Willebrand Factor / Q000494:pharmacology
chemical_list: D011994:Recombinant Proteins; D014841:von Willebrand Factor; D005169:Factor VIII; D007770:L-Lactate Dehydrogenase