title: Haptoglobin subtypes among four different populations.
abstract: Haptoglobin subtypes were analysed by isoelectric focusing in four populations from Colombia, England, Nigeria, and India. There is a wide range of variation of allele frequencies in these four populations: HP*1S = 15-28%, HP*1F = 5-19%, HP*2FS = 54-79%. With the exception of the English, and the Spanish-speaking population of Colombia, all interpopulation comparisons showed significant heterogeneity. There is an extreme variation for the HP*1F allele in different populations, and a possible geographical cline of the HP*2FS allele increasing from west to east. The data presented here suggest that HP subtypes provide a useful anthropogenetic marker for racial differentiation.
authors.affiliation: Department of Human Sciences, Loughborough University of Technology, UK.
authors.forename: S S
authors.initials: SS
authors.lastname: Mastana
authors.forename: J E
authors.initials: JE
authors.lastname: Bernal
authors.forename: G C
authors.initials: GC
authors.lastname: Onyemelukwe
authors.forename: S S
authors.initials: SS
authors.lastname: Papiha
mesh_terms: D000483:Alleles; D002874:Chromosome Mapping; D004739:England; D005819:Genetic Markers; D006242:Haptoglobins / Q000235:genetics*; D006630:Hispanic or Latino; D006801:Humans; D007194:India; D009549:Nigeria; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers; D006242:Haptoglobins