[Should conversion enzyme inhibitors be use in renal insufficiency?].
Several experimental studies have shown an interaction between renin-angiotensin-aldosterone system and erythropoiesis, while several clinical studies in essentially patients with chronic renal failure have reported that ACE-inhibitor interfere with erythropoiesis. The clinical consequences of this effect need to be determined before condemning ACE-inhibitor use in this patients.
Bobrie
G
G
Service de Néphrologie, Centre Hospitalier, Vannes.
D058186:Acute Kidney Injury / Q000503:physiopathology*; D000368:Aged; D000740:Anemia / Q000139:chemically induced; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D004920:Erythropoiesis; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D011086:Polycythemia / Q000628:therapy
D000806:Angiotensin-Converting Enzyme Inhibitors
Faut-il remettre en question l'utilisation des inhibiteurs de l'enzyme de conversion chez les insuffisants rénaux?