title: Incidence and management of catheter-related sepsis in patients receiving home parenteral nutrition.
abstract: Fifty patients, comprising 24 male and 26 female of median age 43 (range 15-67) years, received a total of 2620 patient-months of home parenteral nutrition (median 48 (range 2-130) months). There were 13 episodes of bacterial catheter sepsis (of which the catheter was successfully salvaged by an antibiotic-fibrinolytic 'lock' technique in four cases) and ten of exit-site sepsis (all managed by elective catheter replacement), representing an incidence of 1 septic complication per 113 patient-months of parenteral nutrition. This low incidence of catheter-related sepsis was achieved by strict adherence to established protocols of catheter management.
authors.affiliation: Department of Surgery, University of Manchester, Hope Hospital, Salford, UK.
authors.forename: N
authors.initials: N
authors.lastname: Williams
authors.forename: G L
authors.initials: GL
authors.lastname: Carlson
authors.forename: N A
authors.initials: NA
authors.lastname: Scott
authors.forename: M H
authors.initials: MH
authors.lastname: Irving
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001207:Asepsis; D016470:Bacteremia / Q000517:prevention & control / Q000628:therapy*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016331:Parenteral Nutrition, Home / Q000009:adverse effects*