title: Cytotoxic effects of gutta-percha solvents.
abstract: Cytotoxicity of commonly used gutta-percha solvents was evaluated. Gutta-percha dissolved by chloroform, halothane, or turpentine was evaluated with the radiochromium release method using L929 mouse fibroblast cells. All solvents were toxic. Turpentine was most toxic followed by halothane and chloroform, which caused similar levels of cell injury.
authors.affiliation: Department of Restorative Dentistry and Endodontology, University of Connecticut Health Center, School of Dental Medicine, Farmington.
authors.forename: S V
authors.initials: SV
authors.lastname: Barbosa
authors.forename: D H
authors.initials: DH
authors.lastname: Burkard
authors.forename: L S
authors.initials: LS
authors.lastname: Spångberg
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002725:Chloroform / Q000633:toxicity*; D005347:Fibroblasts / Q000187:drug effects; D006171:Gutta-Percha / Q000737:chemistry* / Q000633:toxicity; D006221:Halothane / Q000633:toxicity*; D051379:Mice; D012086:Reoperation; D012388:Root Canal Irrigants / Q000633:toxicity*; D012997:Solvents / Q000633:toxicity; D014425:Turpentine / Q000633:toxicity*
chemical_list: D012388:Root Canal Irrigants; D012997:Solvents; D002725:Chloroform; D006171:Gutta-Percha; D006221:Halothane; D014425:Turpentine