title: [Prevention of post-ovariectomy osteoporosis in the rat. Comparative study of synthetic salmon calcitonin and eel calcitonin aminosuberic analogue].
abstract: The authors evaluate the efficacy of salmon calcitonin and aminosuberic analogue of eel calcitonin in the prevention of post-oophorectomy osteoporosis in rats. Both drugs, administered at the same dosage, are equally effective in preventing oophorectomy bone loss in rats. Besides, plasma biochemical evaluations demonstrate that calcitonins reduce bone turnover in treated rats, compared with control oophorectomized ones.
authors.affiliation: Servizio Medicina Generale, Istituto Ortopedico Rizzoli, Bologna.
authors.forename: S
authors.initials: S
authors.lastname: Gnudi
authors.forename: A
authors.initials: A
authors.lastname: Zati
authors.forename: R
authors.initials: R
authors.lastname: Giardino
authors.forename: M
authors.initials: M
authors.lastname: Fini
authors.forename: L
authors.initials: L
authors.lastname: Pratelli
authors.forename: M
authors.initials: M
authors.lastname: Orlandi
authors.forename: E
authors.initials: E
authors.lastname: Figus
mesh_terms: D015502:Absorptiometry, Photon; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D015415:Biomarkers; D001862:Bone Resorption / Q000517:prevention & control; D002116:Calcitonin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000627:therapeutic use*; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D015675:Osteocalcin / Q000097:blood; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control*; D010052:Ovariectomy / Q000009:adverse effects; D010758:Phosphorus / Q000097:blood; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D015415:Biomarkers; D015675:Osteocalcin; D010758:Phosphorus; C028815:salmon calcitonin; D002116:Calcitonin; D000469:Alkaline Phosphatase; D002118:Calcium; C012755:elcatonin
vernacular_title: Prevenzione della osteoporosi post-ovariectomia nel ratto. Studio comparativo fra calcitonina sintetíca di salmone e derivato aminosuberico della calcitonina di anguilla.