ELISA seropositivity for Toxocara canis antibodies in Malaysia, 1989-1991.
The laboratory test results for visceral larva migrans (VLM) using ELISA for Toxocara canis antibodies employed by the Institute for Medical Research, Kuala Lumpur, is described. A total of 331 serum samples received from hospitals and general practitioners all over Malaysia were tested. The test utilises excretory-secretory antigens obtained from in vitro culture of second stage T. canis larvae. The overall seropositivity rate was 19.6%, the highest positive rate being in Indians (35.5%), followed by the Malays (14.8%), Chinese (10.9%) and others (29.4%). Seropositivity rate was highest in children below the age of 10; 89% of patients presented with eosinophilia and 93% with VLM syndrome were children.
Hakim
S L
SL
Institute for Medical Research, Jalan Pahang, Kuala Lumpur.
Mak
J W
JW
Lam
P L
PL
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000208:ethnology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007194:India / Q000208:ethnology; D007223:Infant; D007231:Infant, Newborn; D008296:Malaysia; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D017166:Toxocara canis / Q000276:immunology*
D000909:Antibodies, Helminth