Application of the three-dimensional structures of protein target molecules in structure-based drug design.
Greer
J
J
Department of Structural Biology, Abbott Laboratories, Abbott Park, Illinois 60064.
Erickson
J W
JW
Baldwin
J J
JJ
Varney
M D
MD
D003460:Crystallization; D015195:Drug Design; D017320:HIV Protease Inhibitors / Q000737:chemistry; D015497:HIV-1 / Q000201:enzymology; D008958:Models, Molecular; D015394:Molecular Structure; D011506:Proteins / Q000737:chemistry*; D013329:Structure-Activity Relationship; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors
D017320:HIV Protease Inhibitors; D011506:Proteins; D013940:Thymidylate Synthase