[A novel antibiotic of the aureolic acid group. Isolation, physicochemical and biological properties, identification].
An antibiotic complex was extracted from the culture fluid of Streptomyces phaeofaciens, strain 51. By the physicochemical properties it was referred to the group of aureolic acid. The complex was separated to chromatographically pure components by column chromatography. The main component was designated as antibiotic 51-I. Its physicochemical and biological properties were studied. Comparison of the data on the study of antibiotic 51-I with the respective characteristics of the described antibiotics of the group of aureolic acid suggested that antibiotic 51-I is a new representative of this group.
Fedorova
G B
GB
Katrukha
G S
GS
Arkhangel'skai
N M
NM
Laĭko
A V
AV
Symarukova
I G
IG
Tokareva
N L
NL
Davadorzh
B
B
Tsétség
B
B
D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002853:Chromatography, Liquid; D003470:Culture Media; D008926:Plicamycin / Q000737:chemistry*; D013302:Streptomyces / Q000378:metabolism*
D000903:Antibiotics, Antineoplastic; D003470:Culture Media; D008926:Plicamycin
Novyĭ antibiotik iz gruppy aureolovoĭ kisloty. Vydelenie, fiziko-khimicheskie i biologicheskie svoĭstva, identifikatsiia.