title: [Association of platelet aggregation with the extent of myocardial infarction].
abstract: The aim of this study was to evaluate the association between the type of myocardial infarction (MI) and the circulating platelet aggregates [circulating aggregates of thrombocytes (CAT)]. The size of MI was assessed by the maximal values of creatine-kinase (CK). In 80 patients in the acute phase of MI the values of CAT and CK were manifold increased, mostly in 30 patients with anteroseptal MI (CAT 34.1 +/- 8.3%, CK: 920 +/- 340 IU), less markedly in 30 patients with inferior MI (CAT: 25 +/- 6.7%, CK: 739 +/- 263 IU) and in 20 patients with non-Q-wave MI (CAT: 20.7 +/- 1.9%, CK 518 +/- 224 IU). The differences between the groups were significant (p < 0.05). There was a significant linear correlation between CAT and CK in anteroseptal MI (r = 0.57, p < 0.01) and in inferior MI (r = 0.54, p < 0.01), but not in non-Q-wave MI (r = 0.15, p > 0.05). The results are concordant with the hypothesis that thrombotic event contributes more significantly to the pathogenesis of transmural acute myocardial infarction.
authors.affiliation: Klinika za unutarnje bolesti Medicinskog fakulteta u Zagrebu.
authors.forename: D
authors.initials: D
authors.lastname: Mirić
authors.forename: Z
authors.initials: Z
authors.lastname: Rumboldt
authors.forename: D
authors.initials: D
authors.lastname: Eterović
authors.forename: V
authors.initials: V
authors.lastname: Capkun
authors.forename: J
authors.initials: J
authors.lastname: Bagatin
authors.forename: S
authors.initials: S
authors.lastname: Polić
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis / Q000473:pathology*; D010974:Platelet Aggregation
chemical_list: D003402:Creatine Kinase
vernacular_title: Povezanost agregabilnosti trombocita s velicinom infarkta miokarda.