[The hemodynamic effect of thoracic sympathetic ganglion blockade in the anesthetized adult mongrel dogs].
Hemodynamic alterations with the thoracic sympathetic ganglion blockade were elucidated in the anesthetized open-chest dogs, under controlled ventilation with 100% oxygen and receiving fentanyl, pentobarbital and pancuronium administration, and the effect of blockade was assessed by increase in skin-surface temperature at the specific regions of the upper extremity. All dogs with thoracic sympathetic ganglion blockade revealed the increased skin temperature in blocked extremities and decreased skin temperature in the contralateral side with simultaneous compensatory vasoconstriction ("Borrowing-Lending phenomenon"). Four groups were classified according to the side and range of blockade: A-group (right Th7.8 ganglion, N = 17), B-group (left-Th7.8 ganglion, N = 8), C-group (right Th2.3 ganglion, N = 13) and D-group (left-Th2.3 ganglion, N = 10). The hemodynamic variables after the middle thoracic sympathetic ganglion blockade showed no remarkable changes but heart-rate, mean arterial blood pressure and cardiac output decreased significantly with the upper right-side thoracic sympathetic ganglion blockade, and the inhibited circulatory state lasted twenty minutes after blockade. No significant skin temperature changes were observed after blockade among four groups. The results suggest that the patient after upper thoracic sympathetic ganglion blockade should be cared with these circulatory changes in mind.
Yamagami
H
H
Department of Anesthesiology, Nara Medical University, Kashihara.
D000769:Anesthesia, Inhalation; D000818:Animals; D001340:Autonomic Nerve Block; D004285:Dogs; D005728:Ganglia, Sympathetic; D006439:Hemodynamics / Q000502:physiology*; D012881:Skin Temperature; D013909:Thorax / Q000294:innervation*