title: Prognosis of stroke patients undergoing mechanical ventilation.
abstract: OBJECTIVE
  to determine the outcome of stroke patients undergoing mechanical ventilation.
  
  
  METHODS
  retrospective chart review and follow-up telephone interview.
  
  
  METHODS
  medical ICU in a multidisciplinary university hospital.
  
  
  METHODS
  199 stroke patients from 1984-1989 where the final diagnosis was stroke.
  
  
  METHODS
  all patients were admitted for the need of mechanical ventilation.
  
  
  RESULTS
  demographic information, previous relevant diseases, stroke type, general clinical and neurological data, biochemical variables, severity of illness were recorded for the first 24 h following ICU admission. A 1-year follow-up was performed, including mortality and functional status of survivors. Of 170 eventually analyzable patients, 123 (72.4%) died during their ICU stay and 156 (91.8%) during the first year. Three variables were independently associated with one-year mortality: Glasgow score < 10 (p < 0.03), bradycardia (p < 0.001), absence of brainstem reflexes (p < 0.0004).
  
  
  CONCLUSIONS
  overall prognosis of stroke needing mechanical ventilation is poor, strongly linked to symptoms of neurological impairment.
authors.affiliation: Service de Réanimation Médicale, Hôpital Central, Centré Hospitalier Universitaire de Nancy, France.
authors.forename: P
authors.initials: P
authors.lastname: Burtin
authors.forename: P E
authors.initials: PE
authors.lastname: Bollaert
authors.forename: L
authors.initials: L
authors.lastname: Feldmann
authors.forename: L
authors.initials: L
authors.lastname: Nace
authors.forename: P
authors.initials: P
authors.lastname: Lelarge
authors.forename: P
authors.initials: P
authors.lastname: Bauer
authors.forename: A
authors.initials: A
authors.lastname: Larcan
mesh_terms: D002545:Brain Ischemia / Q000401:mortality / Q000628:therapy; D002543:Cerebral Hemorrhage / Q000401:mortality / Q000628:therapy; D002561:Cerebrovascular Disorders / Q000401:mortality* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D016896:Treatment Outcome