title: Prolonged treatment with almitrine for refractory hypoxemia in adult respiratory distress syndrome.
abstract: A 49-year-old man presented with an atypical pneumonia entailing an adult respiratory distress syndrome (ARDS). The refractory hypoxemia caused a myocardial infarction, leading us to try pharmacologic treatments. Almitrine bismesilate (AB) infusion allowed improvement of arterial oxygenation during 115 h without adverse effect. This case is, to our knowledge, the first reported prolonged treatment using AB for hypoxemia due to ARDS.
authors.affiliation: Division of Pneumology, University Hospital, Geneva, Switzerland.
authors.forename: J B
authors.initials: JB
authors.lastname: Thorens
authors.forename: P
authors.initials: P
authors.lastname: Jolliet
authors.forename: J C
authors.initials: JC
authors.lastname: Chevrolet
mesh_terms: D015765:Almitrine / Q000008:administration & dosage*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D000860:Hypoxia / Q000188:drug therapy* / Q000209:etiology; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D011659:Pulmonary Gas Exchange / Q000187:drug effects; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D015765:Almitrine