A multiple dose comparison of ketorolac tromethamine with ibuprofen for analgesic activity.
This study was done to compare a new analgesic ketorolac with ibuprofen in post-operative and post-laparoscopy pain. A total of 40 patients were recruited for the study of which 20 were post-operative and 20 were post-laparoscopy cases. Medication was given over a period of 48 hours after surgery and a pain score based on subjective symptoms was monitored at fixed intervals after each dose. The analgesic efficacy of ketorolac was found to be comparable to that of ibuprofen and the drug was well tolerated in the doses used without any extra medication being required.
Anaokar
S M
SM
Dept. of Pharmacology, Seth GS Medical College, Bombay, Maharashtra.
Parulekar
S V
SV
Thatte
U M
UM
Dahanukar
S A
SA
D000328:Adult; D000700:Analgesics; D004338:Drug Combinations; D006801:Humans; D007052:Ibuprofen; D020911:Ketorolac Tromethamine; D010535:Laparoscopy; D008875:Middle Aged; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000188:drug therapy; D013997:Time Factors; D014046:Tolmetin / Q000031:analogs & derivatives*; D014325:Tromethamine
D000700:Analgesics; D004338:Drug Combinations; D014325:Tromethamine; D020911:Ketorolac Tromethamine; D014046:Tolmetin; D007052:Ibuprofen