In vivo determination of human arterial compliance: preliminary investigation of a new technique.
OBJECTIVE
To obtain more detailed information about the dynamic mechanical properties of human arteries in vivo, using a new technique based on intravascular ultrasound. (IVUS).


METHODS
Arterial compliance was measured in the common and/or external iliac arteries of 6 patients using an IVUS device, concurrently obtained intraarterial pressure measurements, and a video motion analysis system.


RESULTS
Compliance decreased with increasing vessel diameter and mean arterial pressure. Pre- and postangioplasty measurements were obtained in 2 patients but did not demonstrate a consistent change in compliance following angioplasty.


CONCLUSIONS
We conclude that IVUS provides an accurate means for in vivo determination of human arterial compliance, the practical value of which needs to be established.
Hansen
M E
ME
Department of Radiology, Massachusetts General Hospital, Boston 02114.
Yucel
E K
EK
Megerman
J
J
L'Italien
G J
GJ
Abbott
W M
WM
Waltman
A C
AC
D000328:Adult; D000368:Aged; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging / Q000503:physiopathology; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology; D003187:Compliance; D004548:Elasticity; D005260:Female; D006801:Humans; D007083:Iliac Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D018084:Ultrasonography, Interventional