Genetic and molecular dissection of axon pathfinding in the Drosophila nervous system.
Over the past year, several systematic genetic screens designed to identify mutations that specifically disrupt axon pathfinding processes in the Drosophila nervous system have been described. The analysis of mutations isolated in these screens, in concert with ongoing cellular studies and the ever increasing number of identified proteins expressed in the Drosophila nervous system, is providing further insights into the molecular mechanisms of growth cone guidance.
Seeger
M A
MA
Program in Molecular and Cell Biology, Oklahoma Medical Research Foundation, Oklahoma City 73104-5073.
D000818:Animals; D001369:Axons / Q000502:physiology*; D004330:Drosophila / Q000196:embryology / Q000235:genetics* / Q000502:physiology*; D005821:Genetic Techniques; D009046:Motor Neurons / Q000502:physiology; D009154:Mutation; D009412:Nerve Fibers / Q000502:physiology; D009419:Nerve Tissue Proteins / Q000502:physiology; D009424:Nervous System Physiological Phenomena; D009434:Neural Pathways / Q000502:physiology; D009469:Neuromuscular Junction / Q000196:embryology
D009419:Nerve Tissue Proteins