Coexistence of chronic neutrophilic leukemia with light chain myeloma.
A 60-year-old woman who presented with weakness, night sweats, bone pain, easy bruising and weight loss was found to have ecchymoses and hepatosplenomegaly. Blood counts showed persistent neutrophilia of mature cell type with Döhle bodies and toxic granulation. Coexistence of chronic neutrophilic leukemia and multiple myeloma of kappa light chain type was documented by bone marrow examination and immunofixation.
Cehreli
C
C
Department of Hematology, Dokuz Eylul University, School of Medicine, Inciralti, Izmir, Turkey.
Undar
B
B
Akkoc
N
N
Onvural
B
B
Altungoz
O
O
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage; D007145:Immunoglobulin kappa-Chains / Q000652:urine*; D015467:Leukemia, Neutrophilic, Chronic / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D007145:Immunoglobulin kappa-Chains; D005047:Etoposide; D004317:Doxorubicin; D006918:Hydroxyurea