title: Establishing control of refractory hypertension.
abstract: A systematic workup usually will identify a correctable cause. Volume overload due to inadequate medical therapy heads the list; lifestyle changes and renovascular disease are also important. Control should be established gradually, in order to avoid overtreatment and its sequelae. Even when a cause cannot be identified, devising an optimal drug regimen will often at least improve blood pressure.
authors.affiliation: University of Texas Southwestern Medical Center at Dallas.
authors.forename: N M
authors.initials: NM
authors.lastname: Kaplan
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000008:administration & dosage; D001794:Blood Pressure / Q000187:drug effects; D004232:Diuretics / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D008875:Middle Aged
chemical_list: D000959:Antihypertensive Agents; D004232:Diuretics