In vivo 2D 1H NMR of mdx mouse muscle and myoblast cells during fusion: evidence for a characteristic signal of long chain fatty acids.
We have previously demonstrated that 2D 1H NMR is suitable for studying cerebral metabolism. The same technique was used to study the hind leg muscle of normal (C57BL10) and dystrophic (mdx) mice. The results were compared to preliminary results for cultured muscle cells to determine the origin of fatty acid signals.
Gillet
B
B
Laboratoire de RMN Biologique, ICSN-CNRS, Gif-sur-Yvette, France.
Doan
B T
BT
Verre-Serrie
C
C
Barbere
B
B
Berenger
G
G
Morin
S
S
Koenig
J
J
Peres
M
M
Sebille
A
A
Beloeil
J C
JC
D000375:Aging / Q000502:physiology; D000818:Animals; D002459:Cell Fusion; D002478:Cells, Cultured; D005227:Fatty Acids / Q000032:analysis*; D006859:Hydrogen; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D051379:Mice; D008810:Mice, Inbred C57BL; D008818:Mice, Neurologic Mutants; D009132:Muscles / Q000378:metabolism / Q000502:physiology*; D009137:Muscular Dystrophy, Animal / Q000378:metabolism*
D005227:Fatty Acids; D006859:Hydrogen