title: Prevention of hypotony after trabeculectomies with mitomycin.
abstract: Hypotony with reduced a reduced visual acuity is often seen after trabeculectomy with mitomycin. In this study we describe measures such as reattaching the scleral flap with at least seven nylon sutures and the controlled and delayed use of argon laser suture lysis. With these preventative measures the percentage of hypotonies (IOP < or = 6 mmHg) three months after surgery was reduced from 38 to 15% and chronically reduced visual acuity was reduced from 38 to 5%. With these adaptations in the surgical technique the complication rate of trabeculectomies with mitomycin can be markedly reduced without affecting the mean IOP (10.9 mmHg versus 10.8 mmHg) three months after surgery and the percentage of eyes with IOP 18 mmHg or less without medication (94 versus 91%).
authors.affiliation: Glaucoma Center of Eye Clinic, University of Amsterdam, Netherlands.
authors.forename: H C
authors.initials: HC
authors.lastname: Geijssen
authors.forename: E L
authors.initials: EL
authors.lastname: Greve
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D008937:Mitomycins / Q000008:administration & dosage / Q000627:therapeutic use*; D015814:Ocular Hypotension / Q000209:etiology / Q000517:prevention & control*; D012590:Sclera / Q000601:surgery; D013524:Surgical Flaps; D013536:Suture Techniques; D014130:Trabeculectomy / Q000009:adverse effects*; D014792:Visual Acuity
chemical_list: D008937:Mitomycins