[The effect of rifampicin on the metabolism of glucocorticosteroid hormones in patients with tuberculosis].
Endogenic hydrocortisone concentrations were measured radiologically in 98 tuberculous patients to evaluate rifampicin effect on exogenic glucocorticosteroids. In response to the drug administration daily or 3 times a week the hormones underwent inactivation. A twice-a-week regimen proved less inactivating as regards exogenic hormones.
Basov
P V
PV
Galćhanskaia
L D
LD
Spesivtsev
O G
OG
Khokhlova
E P
EP
Ivutina
V P
VP
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000494:pharmacology*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000378:metabolism*
D012293:Rifampin; D006854:Hydrocortisone
Vliianie rifampitsina na metabolizm gliukokortikosteroidnykh gormonov u bolńykh tuberkulezom.