title: [Spontaneous recovery from metastatic cancer of the kidney. Favourable role of Vitamin E?].
abstract: We report about one case of spontaneous healing of metastases of kidney cancer (hypernephroma). The subcutaneous and abdominal metastases appeared 3 years after the discovery of the initial neoplasm and subsequent nephrectomy. Meanwhile the patient developed an adenoma of the prostate, while the neoplasm was in a metastasizing stage. After prostatectomy, he was treated with Ephynal for mild transient incontinence. From then on, we witnessed progressive disappearance of the metastases, until they were completely eradicated. This case is very well documented, with irrefutable histological evidence of the nature of the lesions and of their healing. It adds to the 21 similar cases published worldwide until then. In recent cases, the beneficial role of vitamin D in the treatment of metastases of kidney cancer has been predicted. We have probably demonstrated accidentally that vitamin E, which has some similarities with vitamin D, is a least as effective. In addition, it is a particularly innocuous and cheap medication. This may be an interesting therapeutic improvement, considering that there is no really effective treatment of metastasized kidney cancer, except very heavy Interleukin-based therapies that are both very expensive and hard to bear for the patient.
authors.affiliation: Service de Chirurgie I, Centre Hospitalier, Douarnenez.
authors.forename: G
authors.initials: G
authors.lastname: Crespy
mesh_terms: D000008:Abdominal Neoplasms / Q000556:secondary*; D000236:Adenoma / Q000601:surgery; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D016609:Neoplasms, Second Primary / Q000601:surgery; D009392:Nephrectomy; D011468:Prostatectomy / Q000009:adverse effects; D011471:Prostatic Neoplasms / Q000601:surgery; D012075:Remission, Spontaneous; D012878:Skin Neoplasms / Q000556:secondary* / Q000601:surgery; D014550:Urinary Incontinence, Stress / Q000188:drug therapy / Q000209:etiology; D014810:Vitamin E / Q000627:therapeutic use*
chemical_list: D014810:Vitamin E
vernacular_title: Guérison spontanée de métastases d'un cancer du rein. Rôle bénéfique de la vitamine E?