[Z-100 as radiation mucositis protector in head and neck tumor management].
To study the radioprotective effect of Z-100 against mucositis, twenty-five patients with head and neck malignancies were received external irradiation of 30-61.2 Gy (mean 44.4 Gy) concurrent with Z-100 injection twice a week. Of these cases, an incidence of dysphagia was less than 20% and white coating mucositis below 50%. Frequency of radiation mucositis in these regions was reduced compared to our previous experiences; efficacy of 88%. This combined therapy seems to be a promising method.
Miyashita
T
T
Department of Radiology, Nippon Medical School.
Morita
S
S
Shibuya
H
H
Takeda
M
M
Horiuchi
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008055:Lipids / Q000008:administration & dosage*; D008297:Male; D008351:Mannans / Q000008:administration & dosage*; D008875:Middle Aged; D009061:Mouth Mucosa; D011788:Quality of Life; D011832:Radiation Injuries / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000008:administration & dosage*; D011879:Radiotherapy Dosage; D013280:Stomatitis / Q000517:prevention & control*
D008055:Lipids; D008351:Mannans; D011837:Radiation-Protective Agents; C031208:specific substance maruyama