Presence of anti-Yta antibody in a Yt(a+) patient.
Since 1956 when Cartwright (Yt) was recognized as a new erythrocyte antigenic system, numerous studies about anti-Yta and anti-Ytb antibodies have been published. A number of these studies described the laboratory techniques utilized in antibody identification, while others investigated the clinical importance of anti-Yta, giving variable results. However, most authors agreed upon the homogeneity of expression in this antigenic system. In our study we have described a case regarding 1 Yt(a+) patient with anti-Yta antibody. Family studies indicated inheritance of a variant/variant expression of the Yta antigen from the father.
Mazzi
G
G
Servizio Immunotrasfusionale di Pordenone (USL No. 11) Ospedale Civile, Italia.
Raineri
A
A
Santarossa
L
L
De Roia
D
D
Orazi
B M
BM
D000328:Adult; D000918:Antibody Specificity; D001789:Blood Group Antigens / Q000235:genetics / Q000276:immunology*; D001788:Blood Grouping and Crossmatching; D001803:Blood Transfusion; D004375:Duffy Blood-Group System / Q000235:genetics / Q000276:immunology; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007114:Immunization; D007518:Isoantibodies / Q000097:blood* / Q000235:genetics; D008297:Male; D010641:Phenotype
D001789:Blood Group Antigens; D004375:Duffy Blood-Group System; D007518:Isoantibodies; C061962:anti-Fy(a) antibody