title: Diuretic action of an aqueous extract of Lepidium latifolium L.
abstract: An aqueous extract of Lepidium latifolium L. given orally and intraperitoneally considerably enhanced urinary excretion (UV) in rats with respect to control groups. A slight increase in ion excretion was also observed. Other parameters such as specific gravity, nitrite, pH, glucose, ketone bodies, urobilinogen, and blood were also studied. A good correlation for the dosage rat/man for the aqueous extract was achieved.
authors.affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Navarro
authors.forename: J
authors.initials: J
authors.lastname: Alonso
authors.forename: R
authors.initials: R
authors.lastname: Rodriguez
authors.forename: J
authors.initials: J
authors.lastname: Trujillo
authors.forename: J
authors.initials: J
authors.lastname: Boada
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004232:Diuretics / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D006863:Hydrogen-Ion Concentration; D007274:Injections, Intraperitoneal; D010936:Plant Extracts / Q000008:administration & dosage / Q000302:isolation & purification / Q000494:pharmacology*; D011188:Potassium / Q000652:urine; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000652:urine
chemical_list: D004232:Diuretics; D010936:Plant Extracts; D012964:Sodium; D011188:Potassium