[Acute eye damage from ultraviolet radiation].
The eyes of rabbits were UV-irradiated in a range close to the natural spectrum at a dose of 23.2 kJ/m2 (biologically effective dose 1.3 kJ/m2). The condition of optic media was estimated, as well as the parameters of electroretinogram (ERG) induced by single light stimulus of varying intensity and paired light stimuli with different intervals between them. As a result a distinct photokeratoconjunctivitis developed, the amplitude of the ERG a-wave decreased by 30-50% and that of b-wave by 35%, while the latencies of the both waves and the critical frequency of flashes remained unchanged. The cornea transparency did not decrease markedly even during the period of maximum photokeratoconjunctivitis and the changes in the ERG parameters were mostly due to the retina damage by the indirect effect of UV irradiation.
Strizhizhovskiĭ
A D
AD
Belousov
V V
VV
D000208:Acute Disease; D000818:Animals; D004596:Electroretinography / Q000528:radiation effects; D005131:Eye Injuries / Q000150:complications / Q000503:physiopathology*; D007637:Keratoconjunctivitis / Q000209:etiology / Q000503:physiopathology; D010775:Photic Stimulation / Q000295:instrumentation / Q000379:methods; D010786:Photoreceptor Cells / Q000503:physiopathology / Q000528:radiation effects; D011817:Rabbits; D011833:Radiation Injuries, Experimental / Q000150:complications / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology / Q000528:radiation effects; D014466:Ultraviolet Rays / Q000009:adverse effects*
Ostroe porazhenie glaz ul'trafioletovoĭ radiatsieĭ.