title: Psychomotor performance and antihypertensive treatment.
abstract: 1. The aim of treatment of hypertension is prevention of cardiovascular complications without adverse drug reactions. Psychomotor performance can be measured objectively yet there remains uncertainty concerning the psychomotor effects of antihypertensive drugs during chronic treatment. This uncertainty is partly due to the confounding adverse effects of cerebrovascular disease and hypertension itself. There are as yet insufficient good quality data on psychomotor effects with which to differentiate between the commonly used agents. However, in general, the beneficial effect of lowering blood pressure tends to more than offset any adverse effects of the agent used.
authors.affiliation: Department of Medicine for Elderly People, Orpington Hospital, Bromley Hospitals NHS Trust, Kent.
authors.forename: L
authors.initials: L
authors.lastname: Kalra
authors.forename: C G
authors.initials: CG
authors.lastname: Swift
authors.forename: S H
authors.initials: SH
authors.lastname: Jackson
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D002490:Central Nervous System / Q000187:drug effects; D002986:Clinical Trials as Topic; D004232:Diuretics / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D011597:Psychomotor Performance / Q000187:drug effects*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics