title: Potent, selective, and systemically-available inhibitors of acyl-coenzyme A:cholesterol acyl transferase (ACAT).
authors.affiliation: Central Research, Pfizer Inc., Groton, Connecticut 06340.
authors.forename: P A
authors.initials: PA
authors.lastname: McCarthy
authors.forename: E S
authors.initials: ES
authors.lastname: Hamanaka
authors.forename: C A
authors.initials: CA
authors.lastname: Marzetta
authors.forename: M J
authors.initials: MJ
authors.lastname: Bamberger
authors.forename: B J
authors.initials: BJ
authors.lastname: Gaynor
authors.forename: G
authors.initials: G
authors.lastname: Chang
authors.forename: S E
authors.initials: SE
authors.lastname: Kelly
authors.forename: P B
authors.initials: PB
authors.lastname: Inskeep
authors.forename: J T
authors.initials: JT
authors.lastname: Mayne
authors.forename: T A
authors.initials: TA
authors.lastname: Beyer
mesh_terms: D000634:Aminoquinolines / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology*; D000818:Animals; D002460:Cell Line; D002784:Cholesterol / Q000097:blood; D004285:Dogs; D006801:Humans; D008862:Microsomes, Liver / Q000201:enzymology; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D017207:Rats, Sprague-Dawley; D013237:Stereoisomerism; D002785:Sterol O-Acyltransferase / Q000037:antagonists & inhibitors*
chemical_list: D000634:Aminoquinolines; D011725:Pyridines; C087133:N-(6-(methylthio)quinolin-5-yl)-2-(hexylthio)decanoic acid amide; C087132:CP 113818; D002784:Cholesterol; D002785:Sterol O-Acyltransferase