Myocardial magnesium depletion during cyclosporine treatment, associated with reciprocal calcium overload, can be prevented by plentiful dietary magnesium supply.
Rob
P M
PM
Klinik für Innere Medizin, Medizinische Universität zu Lübeck, Germany.
Goebel
Y
Y
Lebeau
A
A
Classen
H G
HG
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D016572:Cyclosporine / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D008274:Magnesium / Q000097:blood / Q000378:metabolism* / Q000627:therapeutic use; D008275:Magnesium Deficiency / Q000139:chemically induced / Q000517:prevention & control; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley
D016572:Cyclosporine; D008274:Magnesium; D002118:Calcium