title: Chondroitin sulfate proteoglycan-immunoreactivity of lectin-labeled perineuronal nets around parvalbumin-containing neurons.
abstract: Perineuronal nets represent highly specialized glial and glia-associated structures. In this study, a triple fluorescence labeling of chondroitin sulfate proteoglycan-immunoreactive (CSPG-ir) and N-acetylgalactosamine (GalNac)-specific plant lectin Wisteria floribunda agglutinin (WFA) binding net components as well as parvalbumin-immunoreactivity (-ir) was performed. It was shown in the rat cortex, that the same nets frequently surrounding parvalbumin-ir neurons are stained by CSPG-ir as well as by the lectin binding method.
authors.affiliation: Paul Flechsig Institute for Brain Research, Department of Neurochemistry, University of Leipzig, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Härtig
authors.forename: K
authors.initials: K
authors.lastname: Brauer
authors.forename: V
authors.initials: V
authors.lastname: Bigl
authors.forename: G
authors.initials: G
authors.lastname: Brückner
mesh_terms: D000818:Animals; D011508:Chondroitin Sulfate Proteoglycans / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D007124:Immunoenzyme Techniques; D037102:Lectins; D009415:Nerve Net / Q000737:chemistry*; D009474:Neurons / Q000737:chemistry*; D010320:Parvalbumins / Q000032:analysis*; D037121:Plant Lectins; D051381:Rats; D017208:Rats, Wistar; D034781:Receptors, N-Acetylglucosamine
chemical_list: D011508:Chondroitin Sulfate Proteoglycans; D037102:Lectins; D010320:Parvalbumins; D037121:Plant Lectins; D034781:Receptors, N-Acetylglucosamine; C040129:wisteria lectin