Stability of foscarnet sodium in 5% dextrose and 0.9% sodium chloride injections.
The stability of foscarnet sodium injection in 5% dextrose and 0.9% sodium chloride injections was determined using a stability-indicating assay reported in the literature. The solutions were stable for at least 35 days when stored at 25 degrees or 5 degrees C. They remained clear throughout the study and pH values did not change. The solutions were stored in plastic bags as used by patients at home.
Mathew
M
M
Department of Pharmaceutics, University of Houston, TX 77030.
Das Gupta
V
V
Bethea
C
C
D004349:Drug Packaging; D004355:Drug Stability; D017245:Foscarnet / Q000008:administration & dosage / Q000032:analysis*; D005947:Glucose; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D007275:Injections, Intravenous; D012965:Sodium Chloride; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature
D007202:Indicators and Reagents; D012996:Solutions; D017245:Foscarnet; D012965:Sodium Chloride; D005947:Glucose