Effect of exposure to morphine throughout gestation on feminine and masculine adult sexual behaviour in golden hamsters.
Adult female hamsters were treated with a long-acting form of morphine before mating and throughout pregnancy; the drug was gradually withdrawn during lactation. The offspring produced were gonadectomized as adults and tested for their ability to display feminine and masculine sexual behaviour after appropriate hormonal priming. Chronic exposure to morphine during development resulted in males that showed an increase in both feminine and masculine sexual behaviour when compared with controls.
Johnston
H M
HM
Department of Anatomy, University of Glasgow, UK.
Payne
A P
AP
Gilmore
D P
DP
D000818:Animals; D006224:Cricetinae; D005260:Female; D008297:Male; D008431:Maternal-Fetal Exchange; D008647:Mesocricetus; D009020:Morphine / Q000494:pharmacology*; D009919:Orchiectomy; D010052:Ovariectomy; D011247:Pregnancy; D012726:Sexual Behavior, Animal / Q000187:drug effects*
D009020:Morphine