title: Short report: long-term management of peptic ulcer disease with ranitidine in Germany.
abstract: One hundred and twenty-five patients with duodenal ulcer disease were given continuous ranitidine therapy after initial acute healing. Cumulative remission rates indicated that 95% of patients were ulcer-free after 1 year, 89% at 2 years, 81% at 3 years, 70% at 4 years and 60% at 5 and 6 years. Nine patients had a second recurrence after healing of the first. No patient developed an ulcer complication. These results support the view that long-term continuous ranitidine therapy prevents ulcer recurrence and complications.
authors.affiliation: Kreiskrankenhaus Schwetzingen, Abteilung Gastroenterologie, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Simon
authors.forename: E
authors.initials: E
authors.lastname: Schütz
authors.forename: P
authors.initials: P
authors.lastname: Müller
authors.forename: J S
authors.initials: JS
authors.lastname: Dixon
mesh_terms: D004381:Duodenal Ulcer / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D008297:Male; D011899:Ranitidine / Q000008:administration & dosage / Q000627:therapeutic use*; D012737:Sex Factors
chemical_list: D011899:Ranitidine