title: Preclinical evaluation of the reliability of a 50 MeV racetrack microtron.
abstract: OBJECTIVE
  A 50 MeV racetrack microtron has been installed and tested at Memorial Sloan-Kettering Cancer Center. It is designed to execute multi-segment conformal therapy automatically under computer control using scanned X ray and electron beams from 10 to 50 MeV. Prior to acceptance of the machine from the manufacturer, formal reliability testing was carried out. Only in this way could confidence be gained in its usefulness for routine 3D computer-controlled conformal therapy.
  
  
  METHODS
  To assess reliability, a set of 25 multi-segment test cases, each consisting of 10 to 17 fixed segments, was developed. The field arrangements and modalities for some of the test cases were identical to 3D conformal treatments that were being delivered with multiple static fields on conventional linear accelerators at our institution. Other cases were designed to explore reliability under more complex sets of conditions. These cases were "treated" repeatedly during a total period of 45 hours, over 5 days. During the treatments, ion chambers attached to the head of the machine provided dosimetric data for each field. Data from sensors connected to every set-up parameter (for example, couch positions, gantry angle, collimator leaf positions, etc.) were recorded and verified by an external computer.
  
  
  RESULTS
  While preliminary tests indicated an interlock rate of 5%, final reliability test results demonstrated an interlock fault rate of approximately 0.5%. The reproducibility of dosimetric data and geometric setup parameters was within specifications. As an example, leaf position reproducibility in the patient plane was within 0.5 mm for 97% of the setups. The times required to carry out treatments were recorded and compared with the times to carry out identical treatments on a conventional linear accelerator with cerrobend blocks. Areas where additional time savings can be achieved were identified.
  
  
  CONCLUSIONS
  As an integral part of acceptance testing, the Scanditronix MM50 was rigorously tested for reliability. The machine successfully passed these tests, providing increased confidence in its usefulness for routine 3D conformal therapy.
authors.affiliation: Dept. of Medical Physics, Memorial Sloan-Kettering Cancer Center, NY.
authors.forename: M E
authors.initials: ME
authors.lastname: Masterson
authors.forename: G S
authors.initials: GS
authors.lastname: Mageras
authors.forename: T
authors.initials: T
authors.lastname: LoSasso
authors.forename: E
authors.initials: E
authors.lastname: Joreskog
authors.forename: L G
authors.initials: LG
authors.lastname: Larsson
authors.forename: B
authors.initials: B
authors.lastname: Tsirakis
authors.forename: R
authors.initials: R
authors.lastname: Febo
authors.forename: R
authors.initials: R
authors.lastname: Mohan
authors.forename: C C
authors.initials: CC
authors.lastname: Ling
authors.forename: S A
authors.initials: SA
authors.lastname: Leibel
mesh_terms: D006801:Humans; D008297:Male; D009369:Neoplasms / Q000532:radiotherapy; D011878:Radiotherapy / Q000295:instrumentation*; D011879:Radiotherapy Dosage; D011881:Radiotherapy, Computer-Assisted