title: Radionuclide limb blood flow measurements to resolve diagnostic problems in vascular surgery.
abstract: This paper describes the application of radionuclide limb blood flow measurements in 60 patients presenting to the vascular surgeons with exercise-induced leg pain. All patients were considered to be diagnostic problems since either their symptoms were atypical for peripheral vascular disease, or they had normal peripheral pulses and/or a normal ankle/brachial pressure index. Thirty-one patients were ultimately shown to have peripheral vascular disease and underwent treatment. In all these cases the limb blood flow to one or both legs was below the normal range. Twenty-three patients were shown, by myelography, computed tomography or plain radiography, to have orthopaedic disease and in all cases their limb blood flow to both legs was within the normal range. In five patients, the limb blood flow was normal and the symptoms spontaneously resolved, no cause for the leg pain having been found (one patient refused angiography). Radionuclide limb blood flow is a simple and reliable diagnostic test which is superior to the assessment of peripheral pulses or their ankle to brachial pressure index in resolving diagnostic problems in vascular surgery.
authors.affiliation: Department of Medical Physics, St James's University NHS Hospital Trust, Leeds, UK.
authors.forename: A
authors.initials: A
authors.lastname: Parkin
authors.forename: J
authors.initials: J
authors.lastname: Maughan
authors.forename: P J
authors.initials: PJ
authors.lastname: Robinson
authors.forename: D
authors.initials: D
authors.lastname: Wilkinson
authors.forename: M J
authors.initials: MJ
authors.lastname: Kerin
authors.forename: R C
authors.initials: RC
authors.lastname: Kester
mesh_terms: D006801:Humans; D007383:Intermittent Claudication / Q000000981:diagnostic imaging*; D007866:Leg / Q000098:blood supply*; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging / Q000601:surgery; D011877:Radionuclide Imaging; D012016:Reference Values; D012039:Regional Blood Flow; D013668:Technetium Tc 99m Aggregated Albumin
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin