title: The utility of topographic EEG mapping in obstructive sleep apnea syndrome.
abstract: A study was undertaken to determine whether topographic brain mapping of standard EEG and cognitive evoked potentials would provide additional information for the detection of subtle brain abnormalities associated with obstructive sleep apnea. During nocturnal sleep, significant brain activity was detected in frontal regions not usually monitored with standard sleep recordings. Moreover, preliminary results suggest that total brain activity decreased in association with apneic events and depth of O2 desaturation. Also, component asymmetry in the P300 waveform observed in brain areas not typically recorded improved with treatment. We conclude that the use of topographic mapping adds important information to the study of brain function during sleep and sleep apnea.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, New York University/Bellevue Hospital Medical Center, New York.
authors.forename: J A
authors.initials: JA
authors.lastname: Walsleben
authors.forename: E B
authors.initials: EB
authors.lastname: O'Malley
authors.forename: K
authors.initials: K
authors.lastname: Bonnet
authors.forename: R G
authors.initials: RG
authors.lastname: Norman
authors.forename: D M
authors.initials: DM
authors.lastname: Rapoport
mesh_terms: D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D004558:Electric Stimulation; D004569:Electroencephalography; D005071:Evoked Potentials; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D010100:Oxygen / Q000097:blood; D011175:Positive-Pressure Respiration / Q000379:methods; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D010100:Oxygen