[HIV-related nephropathy in children: the situation in Spain].
Analysis of pediatric AIDS surveillance revealed that 395 cases of pediatrics AIDS have been registered in Spain until the end of 1992. This accounts for about 3% of all cases of AIDS, a percentage higher than the cumulative pediatric percentage of 2% observed in USA and the rest of Europe. Although renal diseases is not considered a common clinical manifestation of AIDS, approximately 10% of the adults and 7% of pediatric AIDS patients are affected. To assess the situation of childhood HIV-associated nephropathy (HIVAN) in Spain, a survey of Spanish divisions of Pediatric Nephrology was undertaken in 1990. Three children with renal disease were identified. To know the actual prevalence of renal disease in HIV-infected children two years later, a new survey to 15 Spanish hospitals with divisions in Pediatric Nephrology was performed. The questionnaire included a retrospective analysis of their experience with HIV infected children and renal manifestations. The fourteen centers (93%) that responded to the questionnaire controlled 694 HIV-infected children (Class P-O: 454, Class P-1: 98, Class P-2: 142). Ten of them had screening program to detect renal disease in HIV infected children since 1989. Only two centers reported two new cases, one each, with clinical manifestations of HIV infection and renal disease, but without histologic confirmation one of them. They were two white girls, 24 and 2 months old respectively with proteinuria but without hematuria, chronic renal failure neither hypertension. Both patients died from infectious cause eleven months after and at the time of diagnosis respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
D016263:AIDS-Associated Nephropathy / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D002675:Child, Preschool; D005260:Female; D006679:HIV Seropositivity; D006801:Humans; D007223:Infant; D008297:Male; D011507:Proteinuria / Q000150:complications; D044469:Racial Groups; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology
Nefropatía asociada al virus de inmunodeficiencia humana (VIH) en niños. Situación en España. Grupo Español para el Estudio de la Nefropatía Asociada al Virus de Inmunodeficiencia Humana en el Niño.