title: A case of Trichosporon beigelii endocarditis 8 years after aortic valve replacement.
abstract: We report a case of Trichosporon beigelii endocarditis in a 77-year-old diabetic man who presented with an embolic stroke 8 years ago after a porcine aortic valve replacement. He was treated successfully with amphotericin, rifampin, and replacement of the original porcine valve; however, he died suddenly 8 months later from unknown causes. Blood cultures 2 months prior to death were negative. The first manifestation of the endocarditis was a left hemiparesis followed some days later by a splenic infarction. Transthoracic echocardiography failed to demonstrate the aortic vegetation, which was clearly visualized subsequently by transesophageal echocardiography. The literature on Trichosporon beigelii endocarditis is reviewed.
authors.affiliation: Section of General Medicine, Veterans Affairs Medical Center, Wilkes-Barre, Pennsylvania.
authors.forename: M G
authors.initials: MG
authors.lastname: Sidarous
authors.forename: M V
authors.initials: MV
authors.lastname: O'Reilly
authors.forename: C E
authors.initials: CE
authors.lastname: Cherubin
mesh_terms: D000368:Aged; D001021:Aortic Valve; D001705:Bioprosthesis / Q000009:adverse effects*; D002561:Cerebrovascular Disorders / Q000382:microbiology; D004617:Embolism / Q000382:microbiology; D004696:Endocarditis / Q000175:diagnosis* / Q000382:microbiology*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009181:Mycoses / Q000175:diagnosis*; D016459:Prosthesis-Related Infections / Q000175:diagnosis*; D013159:Splenic Infarction / Q000382:microbiology; D014250:Trichosporon