[Simultaneous occurrence of lupus anticoagulant and acquired "storage pool" disease of thrombocytes].
The authors describe the case of a female patient with a history of simultaneous abortion and deep vein thrombosis as well as moderate bleeding disturbances. Investigations revealed the presence of lupus anticoagulant while a thrombocyte "storage pool" disease was confirmed. This case demonstrates the association of these two haemostatic disturbances, and points to a possible relationship between them. Since detailed analyses failed to demonstrate the presence of antiplatelet antibodies, the authors suggest a possible damaging effect of lupus anticoagulant to the endothelium leading to thrombocyte activation.
Soltész
P
P
Debreceni Orvostudományi Egyetem III. sz. Belgyógyászati Klinika.
Zeher
M
M
Muszbek
L
L
Szegedi
G
G
D000022:Abortion, Spontaneous; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000276:immunology*; D004107:Dilatation and Curettage; D005260:Female; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000276:immunology*; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000276:immunology*; D010974:Platelet Aggregation; D010981:Platelet Storage Pool Deficiency / Q000150:complications / Q000276:immunology*; D011247:Pregnancy
D016682:Lupus Coagulation Inhibitor
Lupus anticoagulans és szerzett thrombocyta "storage pool" megbetegedés egyidejü elöfordulása.