Twin concordance for congenital and adult-onset psychosis: a preliminary study of the validity of a novel classification of schizophrenia.
As a test of the hypothesis that the psychoses can be divided into congenital and adult-onset forms, we applied operational criteria for these two disorders to the case summaries of 24 monozygotic and 33 dizygotic schizophrenic twin pairs. Our results indicate that the reliability and validity of this novel classification are comparable with the best of the existing systems and support further investigation of the hypothesis.
Corrigall
R J
RJ
Maudsley Hospital, London, United Kingdom.
Murray
R M
RM
D000328:Adult; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D004200:Diseases in Twins / Q000235:genetics* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D010641:Phenotype; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011618:Psychotic Disorders / Q000145:classification / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology; D015203:Reproducibility of Results; D012307:Risk Factors; D012559:Schizophrenia / Q000145:classification / Q000175:diagnosis / Q000235:genetics*; D012565:Schizophrenic Psychology; D014429:Twins, Dizygotic / Q000235:genetics / Q000523:psychology; D014430:Twins, Monozygotic / Q000235:genetics / Q000523:psychology