title: Prevention of anaphylactic-anaphylactoid reactions to anesthetics in high-risk allergic patients.
abstract: To confirm the role of preventive procedures in high-risk allergic patients, immunological tests in vivo for anesthetics were carried out in 251 atopic patients. The 6-month follow-up showed a complete absence of adverse reactions during the clinical use of hypnotic and muscle relaxant drugs. In the case of local anesthetics, five adverse reactions were observed after dental treatment--four were related to a psychogenic mechanism, and one could not be clearly linked to the local anesthetic. It is possible to confirm that the use of a tested drug that yields negative results has a lower probability of inducing anaphylactic-anaphylactoid reactions during anesthesia.
authors.affiliation: Department of Clinical Pathophysiology, Unit of Anaesthesiology and Intensive Care, University of Florence, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Lorenzi
authors.forename: M
authors.initials: M
authors.lastname: Marsili
authors.forename: G
authors.initials: G
authors.lastname: Manetta
authors.forename: M
authors.initials: M
authors.lastname: Linden
authors.forename: S
authors.initials: S
authors.lastname: Boncinelli
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced / Q000517:prevention & control*; D000766:Anesthesia, Dental / Q000009:adverse effects*; D000768:Anesthesia, General / Q000009:adverse effects; D000777:Anesthetics / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000009:adverse effects; D002648:Child; D017742:Dental Care for Chronically Ill; D004342:Drug Hypersensitivity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000777:Anesthetics; D000779:Anesthetics, Local