Identification of cDNAs encoding bovine cyclin B and Cdk1/Cdc2.
cDNA sequences encoding homologs of cyclin B and Cdk1/Cdc2 were isolated from bovine blastocyst-stage embryos produced in vitro. The bovine CycB sequence is 1548 nucleotides (nt) in length and contains the conserved motif 'FLRRXSK', characteristic for known cyclin B proteins. The deduced protein contains 427 amino acids (aa) and has an estimated mass of 47,653 Da. The bovine cdk1/cdc2 sequence is 1275 nt in length and contains the highly conserved motif 'EGVPSTAIREISLLKE'. The deduced protein contains 297 aa (33,931 Da).
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Department of Animal Science, North Carolina State University, Raleigh 27695-7621.
Farin
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D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001755:Blastocyst; D016203:CDC2 Protein Kinase / Q000235:genetics*; D002417:Cattle; D003001:Cloning, Molecular; D016213:Cyclins / Q000235:genetics*; D018076:DNA, Complementary; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data
D016213:Cyclins; D018076:DNA, Complementary; D016203:CDC2 Protein Kinase