title: Changes of pineal N-acetyltransferase activity in gamma irradiated rats.
abstract: Male Wistar rats were exposed to whole body irradiation with 14.35 Gy gamma rays after the adaptation to light/dark cycle (LD 12:12). Three groups of rats were examined: A) rats irradiated in the night and placed in the 12 h LD cycle again, B) rats irradiated in the day-time and placed in the 12 h LD cycle, and C) rats irradiated in the night and kept in constant darkness. All analyses were carried out in the dark. Radiation enhanced the activity of pineal N-acetyltransferase 3-4 days after exposure in all groups, in the C group significantly on the 4th day. Different light regimens during and after irradiation did not to affect the activity of this key enzyme of melatonin synthesis substantially.
authors.affiliation: Institute of Animal Physiology, Faculty of Science, Safárik University, Kosice, Slovak Republic.
authors.forename: M
authors.initials: M
authors.lastname: Kassayová
authors.forename: E
authors.initials: E
authors.lastname: Ahlersová
authors.forename: I
authors.initials: I
authors.lastname: Ahlers
mesh_terms: D000818:Animals; D001191:Arylamine N-Acetyltransferase / Q000378:metabolism*; D005720:Gamma Rays; D008297:Male; D010870:Pineal Gland / Q000201:enzymology / Q000528:radiation effects*; D051381:Rats; D017208:Rats, Wistar; D014916:Whole-Body Irradiation
chemical_list: D001191:Arylamine N-Acetyltransferase