title: [Infection in genitourinary cancer patients during cancer chemotherapy].
abstract: To examine the frequency and the type of infection during cancer chemotherapy in the urological field, we studied the causes of fever in 67 patients with genitourinary cancer. Twenty-six patients had developed a fever of higher than 38 degrees C. Although fever without proven infection was seen in 11 patients (42.3%), fever caused by pyelonephritis was the most common infection. There was a relationship between fever and the presence of hydronephrosis. Fever was observed more often in patients with a leucocyte count of less than 2,000 white blood cell/mm3. In conclusion, we recommend the interruption of cancer chemotherapy or the use of granulocyte colony-stimulating factor for the prevention of infection, when the leukocyte count is less than 2,000 cell/mm3, especially in patients with hydronephrosis.
authors.affiliation: Department of Urology, Gifu University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Komeda
authors.forename: A
authors.initials: A
authors.lastname: Saitoh
authors.forename: T
authors.initials: T
authors.lastname: Deguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Ban
authors.forename: Y
authors.initials: Y
authors.lastname: Kawada
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000209:etiology*; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology; D016867:Immunocompromised Host; D007970:Leukopenia / Q000139:chemically induced; D008297:Male; D011704:Pyelonephritis / Q000209:etiology; D014552:Urinary Tract Infections / Q000209:etiology*; D014565:Urogenital Neoplasms / Q000188:drug therapy* / Q000276:immunology