title: Presenile-onset cerebral adrenoleukodystrophy presenting as Balint's syndrome and dementia.
abstract: We describe a patient with presenile-onset cerebral adrenoleukodystrophy presenting as Balint's syndrome and dementia. There were demyelinating MRI changes in the parieto-occipital white matter bilaterally, including the splenium of the corpus callosum. Therapeutic trials using 1-deamino-(8-D-arginine)-vasopressin, very long-chain fatty acid-free diet, and gamma-globulin were of no benefit.
authors.affiliation: First Department of Internal Medicine, Kumamoto University School of Medicine, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Uyama
authors.forename: H
authors.initials: H
authors.lastname: Iwagoe
authors.forename: J
authors.initials: J
authors.lastname: Maeda
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Terasaki
authors.forename: M
authors.initials: M
authors.lastname: Ando
mesh_terms: D000326:Adrenoleukodystrophy / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D003704:Dementia / Q000209:etiology*; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D014960:X Chromosome