[Angiomyofibroblastoma of the lower genital tract in women].
Angiomyofibroblastoma (AMF) was described recently as a benign tumour with histology very similar to pelvic aggressive angiomyxoma (AMM). Cases from vulva and scrotum are known for the time being. Two cases of AMF were presented, one quite unusual from vaginal portion of uterine cervix. Both cases had typical histology with biphasic structure of proliferating vessels with various diameter and of stromal myofibroblasts with a desmin positive and actin negative immunophenotype. The same expression was found in subepithelial connective layer of vaginal mucosa which is supposed to be the source of AMF. A close histogenetic relation of AMF and AAM was discussed because of their lightmicroscopical and immunohistochemical overlapping.
Zámecník
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Oddelenie patológie NsP, Trencín.
Michal
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D000328:Adult; D018229:Angiomyoma / Q000473:pathology; D005260:Female; D006801:Humans; D009232:Myxoma / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014625:Vaginal Neoplasms / Q000473:pathology*
Angiomyofibroblastóm dolného genitálneho traktu zeny.