[Analysis of the relationship between the effect of growth hormone therapy and the width of the radial metaphysis].
A radio-dense metaphyseal band (MB) of different width is present at the distal end of the radius in growing children. Authors studied 30 prepubertal children before and after one and two years of treatment by recombinant human growth hormone (rhGH). They examined the relationship between the MB, bone age (BA), height velocity (HV) and insulin like growth factor-I (IGF-I). However all the four parameters showed significant change in the study period, correlation was found only after the second year of treatment between the change MB and IGF-I levels. Authors suggest that the regulation of bone growth in these children can be compared only after two years to the normally growing children.
Tar
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Budai Gyermekkórház-Rendelöintézet II, Gyermekosztály.
Szécsényi Nagy
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I
Péter
F
F
D002648:Child; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy / Q000378:metabolism; D013006:Growth Hormone / Q000031:analogs & derivatives* / Q000172:deficiency / Q000494:pharmacology / Q000627:therapeutic use; D019382:Human Growth Hormone; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008297:Male; D011884:Radius / Q000033:anatomy & histology / Q000187:drug effects / Q000254:growth & development*; D011994:Recombinant Proteins / Q000494:pharmacology / Q000627:therapeutic use*
D011994:Recombinant Proteins; D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone
A növekedési hormon kezelés hatása és a radiális metaphysis szélessége közötti összefüggés elemzése.