[CA 125 in diagnosis and prognosis of epithelial ovarian cancer].
In 59 women with epithelial ovarian cancer serum CA 125 was determined and they were then followed for 3 years. In those with active disease, mean serum CA 125 (289 units/ml) and positivity rate (85%) were significantly higher than in those without evidence of disease (44 units/ml and 17%, p = 0.001 and p < 0.001, respectively). Actuarial 3-year survival curves were calculated according to CA 125 serum level. 91% of those with CA 125 lower than 35 units/ml survived 3 years, as compared to 40% of those with CA 125 levels higher than 35 units/ml (p < 0.01). In ovarian cancer CA 125 serum level correlates with the state of the disease and can be used in the prediction of 3-year survival.
Cohen
A D
AD
Oncology Dept., Soroka Medical Center, Beer Sheba.
Piura
B
B
Cohen
Y
Y
Shoenfeld
Y
Y
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000401:mortality; D011379:Prognosis; D015996:Survival Rate; D013997:Time Factors
D015295:Antigens, Tumor-Associated, Carbohydrate