title: Diversity of the P2 protein among nontypeable Haemophilus influenzae isolates.
abstract: The genes for outer membrane protein P2 of four nontypeable Haemophilus influenzae strains were cloned and sequenced. The derived amino acid sequences were compared with the outer membrane protein P2 sequence from H. influenzae type b MinnA and the sequences of P2 from three additional nontypeable H. influenzae strains. The sequences were 76 to 94% identical. The sequences had regions with considerable variability separated by regions which were highly conserved. The variable regions mapped to putative surface-exposed loops of the protein.
authors.affiliation: Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.
authors.forename: J
authors.initials: J
authors.lastname: Bell
authors.forename: S
authors.initials: S
authors.lastname: Grass
authors.forename: D
authors.initials: D
authors.lastname: Jeanteur
authors.forename: R S
authors.initials: RS
authors.lastname: Munson
mesh_terms: D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry* / Q000235:genetics; D003001:Cloning, Molecular; D004269:DNA, Bacterial / Q000737:chemistry; D006193:Haemophilus influenzae / Q000737:chemistry*; D008969:Molecular Sequence Data
chemical_list: D001425:Bacterial Outer Membrane Proteins; D004269:DNA, Bacterial