title: Malignant glioma: patterns of failure following individually tailored limited volume irradiation.
abstract: Treatment outcome was analyzed for 66 patients with malignant glioma treated with individually CT-planned multifield irradiation techniques. Total doses of 60 Gy were given, with the planning target volume (PTV) including 2 cm beyond the tumour indicated by preoperative CT examination. Median survival was 14 months, and 86% of recurrences occurred in the treated volume. Our results suggest that the used PTV and radiation technique should be appropriate in radiotherapy of malignant glioma.
authors.affiliation: Department of Radiotherapy, University of Tuebingen, Germany.
authors.forename: C F
authors.initials: CF
authors.lastname: Hess
authors.forename: J C
authors.initials: JC
authors.lastname: Schaaf
authors.forename: R D
authors.initials: RD
authors.lastname: Kortmann
authors.forename: M
authors.initials: M
authors.lastname: Schabet
authors.forename: M
authors.initials: M
authors.lastname: Bamberg
mesh_terms: D001254:Astrocytoma / Q000532:radiotherapy; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D005909:Glioblastoma / Q000532:radiotherapy; D005910:Glioma / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011880:Radiotherapy Planning, Computer-Assisted; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure