The influence of respiration induced motion of the kidneys on the accuracy of radiotherapy treatment planning, a magnetic resonance imaging study.
An MRI study has been performed to determine the respiration induced motion of the kidneys. Under normal respiration conditions displacements of the left and right kidney varied from 2 to 24 mm and 4 to 35 mm, respectively. Under forced respiration conditions displacements were larger and ranged from 10 to 66 mm for the left kidney and 10 to 86 mm for the right kidney. The influence of kidney motion on the radiation dose was determined for patients irradiated on the total abdomen for ovarian cancer with shielding of the kidneys during part of the treatment. The kidney motion resulted in a larger fraction of the kidney volume receiving a dose between 20 and 22 Gy.
Moerland
M A
MA
Department of Radiotherapy, University Hospital Utrecht, The Netherlands.
van den Bergh
A C
AC
Bhagwandien
R
R
Janssen
W M
WM
Bakker
C J
CJ
Lagendijk
J J
JJ
Battermann
J J
JJ
D000328:Adult; D005260:Female; D006801:Humans; D007668:Kidney / Q000502:physiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009038:Motion; D011878:Radiotherapy / Q000379:methods*; D012119:Respiration / Q000502:physiology*