title: Scavenging action of propolis extract against oxygen radicals.
abstract: The ethanolic extracts of two types of cuban propolis (R and P) showed a similar manner of scavenging action against different species of oxygen radicals which were generated by specific chemical reactions. Chemiluminescence produced by superoxide generated from the xanthine-xanthine oxidase reaction was 50% inhibited by approximately 5 micrograms/ml of propolis R and 9.5 micrograms/ml of propolis P and by catechin (0.15 micrograms/ml) and superoxide dismutase (72 ng/ml). Alkoxy radical scavenging effect was similar to that produced by 0.11 micrograms/ml of alpha-tocopherol: inhibition of chemiluminescence by 50% was caused by approximately 0.6 micrograms/ml of both propolis preparations. The results indicate that the antioxidative properties of both propolis could be attributed to their free radical scavenging activity against alkoxy radicals and to a lesser degree against superoxide.
authors.affiliation: National Center for Scientific Research, Clinical Biochemistry Department, Playa, La Habana, Cuba.
authors.forename: C
authors.initials: C
authors.lastname: Pascual
authors.forename: R
authors.initials: R
authors.lastname: Gonzalez
authors.forename: R G
authors.initials: RG
authors.lastname: Torricella
mesh_terms: D002392:Catechin / Q000494:pharmacology; D004347:Drug Interactions; D016166:Free Radical Scavengers; D008163:Luminescent Measurements; D011429:Propolis / Q000302:isolation & purification / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000378:metabolism; D014969:Xanthine Oxidase / Q000378:metabolism; D014970:Xanthines / Q000378:metabolism
chemical_list: D016166:Free Radical Scavengers; D014970:Xanthines; D002392:Catechin; D011429:Propolis; D013482:Superoxide Dismutase; D014969:Xanthine Oxidase