title: Scanning electron microscopic study of thrombus formation in an end-to-side anastomosis of the rat carotid artery.
abstract: The healing of conventional microvascular end-to-side anastomoses has been reported in several studies. The authors studied thrombus formation under scanning electron microscopy (SEM) in an end-to-side anastomotic model in rat carotid arteries. Twenty anastomoses were carried out with 10-0 nylon interrupted sutures. Thrombus formation was evaluated 30 min after clamp release. The findings indicated that the first 30 min are the most critical time for thrombus formation. Thrombi underwent partial lysis or embolization after this time, and gross intraluminal thrombi did not recur. Thrombus formation was studied at four different sites in the end-to-side anastomoses. The sites of needle holes and sutures were primary locations for thrombocyte adhesions and aggregations in normal, vascular anastomoses.
authors.affiliation: Center for Microsurgery, University of Leuven, Gasthuisberg, Belgium.
authors.forename: W D
authors.initials: WD
authors.lastname: Boeckx
authors.forename: V V
authors.initials: VV
authors.lastname: Haribhakti
authors.forename: L
authors.initials: L
authors.lastname: Bosmans
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects; D000818:Animals; D002341:Carotid Artery Thrombosis / Q000209:etiology / Q000473:pathology*; D017536:Carotid Artery, Common / Q000601:surgery* / Q000648:ultrastructure*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008866:Microsurgery / Q000009:adverse effects; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors