title: Some considerations concerning the dose and schedule of 5FU and leucovorin: toxicities of two dose schedules from the intergroup colon adjuvant trial (INT-0089).
authors.affiliation: University of Pennsylvania Cancer Center, Philadelphia.
authors.forename: D G
authors.initials: DG
authors.lastname: Haller
authors.forename: M
authors.initials: M
authors.lastname: Lefkopoulou
authors.forename: J S
authors.initials: JS
authors.lastname: Macdonald
authors.forename: R S
authors.initials: RS
authors.lastname: Mayer
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects; D005500:Follow-Up Studies; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D002955:Leucovorin; D005472:Fluorouracil