Short report: long-term management of peptic ulcer disease with ranitidine in Germany.
One hundred and twenty-five patients with duodenal ulcer disease were given continuous ranitidine therapy after initial acute healing. Cumulative remission rates indicated that 95% of patients were ulcer-free after 1 year, 89% at 2 years, 81% at 3 years, 70% at 4 years and 60% at 5 and 6 years. Nine patients had a second recurrence after healing of the first. No patient developed an ulcer complication. These results support the view that long-term continuous ranitidine therapy prevents ulcer recurrence and complications.
Simon
B
B
Kreiskrankenhaus Schwetzingen, Abteilung Gastroenterologie, Germany.
Schütz
E
E
Müller
P
P
Dixon
J S
JS
D004381:Duodenal Ulcer / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D008297:Male; D011899:Ranitidine / Q000008:administration & dosage / Q000627:therapeutic use*; D012737:Sex Factors
D011899:Ranitidine