title: The fragile-X syndrome: a growing gene causing familial intellectual disability.
abstract: The fragile-X syndrome is the most common cause of familial intellectual disability. Recently, the gene related to the fragile-X syndrome [the 'fragile-X mental retardation'-1 (FMR-1) gene] has been isolated. In this review, clinical and molecular aspects of the fragile-X syndrome, current benefits and future prospects are discussed.
authors.affiliation: Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands.
authors.forename: L B
authors.initials: LB
authors.lastname: De Vries
authors.forename: D J
authors.initials: DJ
authors.lastname: Halley
authors.forename: B A
authors.initials: BA
authors.lastname: Oostra
authors.forename: M F
authors.initials: MF
authors.lastname: Niermeijer
mesh_terms: D005260:Female; D005600:Fragile X Syndrome / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology; D006580:Genetic Carrier Screening; D005820:Genetic Testing; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology; D007360:Intelligence / Q000235:genetics; D008297:Male; D010375:Pedigree; D010641:Phenotype