title: Citrobacter meningitis in adults.
abstract: Citrobacter meningitis is an uncommon infection of neonates and young children. It is rarely seen in adults. We describe a 46-year-old man with a mixed bacterial meningitis caused by C. diversus and Klebsiella oxytoca and a 64-year-old woman with C. freundii meningitis. Review of the English-language literature revealed only 2 adult patients with C. diversus meningitis and another 2, with C. freundii meningitis. The ages of these 6 aforementioned patients ranged from 31 to 84 years. Multiple facial fractures, neurosurgical procedures, alcoholism and diabetes mellitus were predisposing conditions. Among the 5 patients whose outcome was known, antibiotic therapy was successful in 4 but failed in 1. This study emphasizes that almost any of the gram-negative bacilli can cause serious infection of the central nervous system in adults in the proper setting.
authors.affiliation: Department of Neurology, Chang Gung Memorial Hospital and Chang Gung Medical College, Taipei, Taiwan.
authors.forename: L M
authors.initials: LM
authors.lastname: Tang
authors.forename: S T
authors.initials: ST
authors.lastname: Chen
authors.forename: T N
authors.initials: TN
authors.lastname: Lui
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002954:Citrobacter / Q000187:drug effects; D016971:Citrobacter freundii / Q000187:drug effects; D004756:Enterobacteriaceae Infections / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy / Q000209:etiology; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents