167-A, a new antibiotic produced by a mutant of an inactive wild strain of Amycolata autotrophica.
Two related antibiotics, 167-A and 167-B, were isolated from the fermentation broth of a mutant of an inactive wild strain of Amycolata autotrophica. Antibiotic 167-B was found to be cervinomycin A2; antibiotic 167-A is a new representative of the same group and has the structure of 18-O-demethyl cervinomycin A2.
Malkina
N D
ND
Institute of New Antibiotics, Moscow, Russia.
Dudnik
Y V
YV
Lysenkova
L N
LN
Lazhko
E I
EI
Galatenko
O A
OA
Katrukha
G S
GS
D000192:Actinomycetales / Q000145:classification / Q000378:metabolism*; D018943:Anthracyclines; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000145:classification / Q000302:isolation & purification / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005285:Fermentation; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D016296:Mutagenesis
C087128:18-O-demethylcervinomycin A2; D018943:Anthracyclines; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; C035628:cervinomycin A2