title: Changes of myocardial myoglobin, myosin and creatine kinase in cases of sudden nocturnal death syndrome.
abstract: Myoglobin, myosin creatine kinase MM (CK-MM), creatine kinase BB(CK-BB) in cardiac muscle and H chain of myosin in atrial and ventricular muscle were studied in specimens from 8 patients who died of sudden nocturnal death syndrome (SNDS) by avidin-biotin complex (ABC) method to investigate the possible early or very early myocardial ischemia in the syndrome. Hematoxylin-eosin staining was conducted for comparison. The results showed evident loss of CK-MM, CK-BB, myoglobin and myosin from cardiac muscle cells, indicating that occurrence of SNDS is closely associated with acute myocardial ischemia.
authors.affiliation: Department of Forensic Pathology, Faculty of Forensic Medicine, China Medical University, Shenyang.
authors.forename: B L
authors.initials: BL
authors.lastname: Zhu
authors.forename: D W
authors.initials: DW
authors.lastname: Guan
authors.forename: D X
authors.initials: DX
authors.lastname: Li
authors.forename: O
authors.initials: O
authors.lastname: Tohru
authors.forename: N
authors.initials: N
authors.lastname: Taizo
mesh_terms: D000328:Adult; D003402:Creatine Kinase / Q000378:metabolism*; D016757:Death, Sudden, Cardiac / Q000209:etiology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D009211:Myoglobin / Q000378:metabolism*; D009218:Myosins / Q000378:metabolism*; D013577:Syndrome
chemical_list: D007527:Isoenzymes; D009211:Myoglobin; D003402:Creatine Kinase; D009218:Myosins