Pregnancy-induced hypertensive disorders.
The concept that endothelial cell activation and injury constitutes the key pathogenetic event is receiving increasing support, but the causative factor or factors are, as yet, unclear. The search for a reliable and clinically useful test to identify pregnant women at risk continues. No definitive conclusions can yet be drawn as to the efficacy and safety of low-dose aspirin prophylaxis. Monitoring of maternal-fetal condition, careful consideration of maternal and perinatal risks, and a balanced decision to continue or terminate pregnancy are key elements of clinical management.
Wallenburg
H C
HC
Institute of Obstetrics and Gynecology, Erasmus University Medical School, Rotterdam, The Netherlands.
Visser
W
W
D000959:Antihypertensive Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D004730:Endothelium, Vascular / Q000293:injuries; D005260:Female; D005323:Fetal Monitoring; D006801:Humans; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D011247:Pregnancy; D011295:Prenatal Care / Q000379:methods; D012307:Risk Factors
D000959:Antihypertensive Agents; D001241:Aspirin