The Drosophila melanogaster homolog of ribosomal protein S18.
The sequence of the cDNA encoding the Drosophila melanogaster homolog of the human and rat small-subunit ribosomal protein, S18 (rpS18), is presented. The deduced 152-amino-acid (aa) sequence exhibits 76% identity to that of the human and rat rpS18 (152 aa), and is, like them, a member of the larger rpS13 family which includes archaebacterial, eubacterial and plant mitochondrial (mt) rpS13. The D. melanogaster rpS18 gene is single copy and maps at 56F, a chromosome region encompassing a previously characterised Minute locus, M(2)56F. The rpS18 gene gives rise to a single 700-nucleotide transcript present throughout development. A comparison of the rpS13 family members suggests that conservation is greatest at the N- and C-termini, whilst additional insertions are present in the Drosophila, mammalian and archaebacterial proteins relative to the eubacterial and plant mt proteins.
Garwood
J
J
Institut Jacques Monod, Paris, France.
Lepesant
J A
JA
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary; D004275:DNA, Ribosomal; D004331:Drosophila melanogaster / Q000235:genetics*; D017344:Genes, Insect; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D012269:Ribosomal Proteins / Q000235:genetics*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D018076:DNA, Complementary; D004275:DNA, Ribosomal; D012269:Ribosomal Proteins