title: [Anaphylaxis caused by chlorhexidine following cystoscopy or urethral catheterization].
abstract: Since 1983 the Netherlands Centre for Monitoring of Adverse Reactions to Drugs received 6 reports of anaphylaxis due to a chlorhexidine-containing lubricant used during cystoscopy or urinary catheterization. One case was described earlier. An accidental rechallenge in two patients was positive. In 5 cases, the causal relationship with chlorhexidine was confirmed by a positive reaction to intracutaneous testing. Although this adverse reaction is probably rare, medical practitioners should be aware of the possibility that a severe anaphylactic reaction may occur during use of these products.
authors.affiliation: Bureau Bijwerkingen Geneesmiddelen, Rijswijk.
authors.forename: L E
authors.initials: LE
authors.lastname: Visser
authors.forename: J H
authors.initials: JH
authors.lastname: Veeger
authors.forename: M H
authors.initials: MH
authors.lastname: Roovers
authors.forename: E
authors.initials: E
authors.lastname: Chan
authors.forename: B H
authors.initials: BH
authors.lastname: Stricker
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D002710:Chlorhexidine / Q000009:adverse effects*; D002974:Clemastine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
chemical_list: D000305:Adrenal Cortex Hormones; D002974:Clemastine; D002710:Chlorhexidine
vernacular_title: Anafylaxie door chloorhexidine na cystoscopie of urethrale catheterisatie.