Interleukin-3 stimulates prostaglandin E2 release by human fetal membranes at term gestation.
The effect of interleukin-3 (IL-3) on prostaglandin E2 (PGE2) release by human fetal membranes at term gestation was evaluated. It was found that interleukin-3 stimulates in vitro prostaglandin E2 release by these gestational tissues, suggesting that interleukin-3 might be involved in the regulation of arachidonic acid metabolism in the fetal membranes.
Pasetto
N
N
Department of Obstetrics and Gynecology, II University of Rome, Italy.
Ticconi
C
C
Zicari
A
A
Pontieri
G
G
Piccione
E
E
D016718:Arachidonic Acid / Q000378:metabolism; D015232:Dinoprostone / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005321:Extraembryonic Membranes / Q000187:drug effects* / Q000276:immunology / Q000502:physiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D066298:In Vitro Techniques; D007377:Interleukin-3 / Q000008:administration & dosage / Q000494:pharmacology*; D007743:Labor, Obstetric / Q000502:physiology; D011247:Pregnancy; D011493:Protein Kinase C / Q000378:metabolism
D007377:Interleukin-3; D016718:Arachidonic Acid; D011493:Protein Kinase C; D015232:Dinoprostone