title: A comparison of the susceptibility of Djallonké sheep and West African Dwarf goats to experimental infection with two different strains of Trypanosoma congolense.
abstract: Two cloned strains of Trypanosoma congolense, of West and East African origin, were used to infect by intradermal inoculation two groups of young adult female Djallonké sheep and West African Dwarf goats. For a 3 month period post-infection, packed red cell volume (PCV), parasitaemia, body weight and clinical parameters were followed to evaluate their trypanotolerant nature and to control the pathogenicity of the two strains of T. congolense. Although the West African strain of T. congolense was more pathogenic than the East African strain, it seemed that the Djallonké sheep and the West African Dwarf goats, despite high levels of parasitaemia and a concomitant drop in PCV, showed a high degree of trypanotolerance, as reflected by zero mortality and an increase in body weight during 12 weeks of observation.
authors.affiliation: International Trypanotolerance Centre (ITC), Banjul, Gambia.
authors.forename: S
authors.initials: S
authors.lastname: Osaer
authors.forename: B
authors.initials: B
authors.lastname: Goossens
authors.forename: D J
authors.initials: DJ
authors.lastname: Clifford
authors.forename: S
authors.initials: S
authors.lastname: Kora
authors.forename: M
authors.initials: M
authors.lastname: Kassama
mesh_terms: D000818:Animals; D001835:Body Weight; D004198:Disease Susceptibility; D005243:Feces / Q000469:parasitology; D005260:Female; D015511:Goat Diseases / Q000097:blood / Q000276:immunology*; D006041:Goats; D006400:Hematocrit / Q000662:veterinary; D010270:Parasite Egg Count / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood / Q000276:immunology*; D014348:Trypanosoma congolense / Q000472:pathogenicity*; D014353:Trypanosomiasis, African / Q000097:blood / Q000276:immunology / Q000662:veterinary*