title: [Synthetic mineralocorticoid, clinical application of fludrocortisone acetate (Florinef)].
abstract: Fludrocortisone acetate (Florinef), a 9 alpha-fluorinated derivative of hydrocortisone, has strong mineralocorticoid activity. From the calculated values in a tracer study, the divided dose regimen is recommended. Florinef has been widely used in the treatment of salt-wasting congenital adrenal hyperplasia (CAH). A tentative guideline for the treatment of salt-wasting CAH was described and its usefulness was discussed.
authors.affiliation: Department of Pediatrics, Hamamatsu University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Igarashi
mesh_terms: D000224:Addison Disease / Q000188:drug therapy*; D000284:Administration, Oral; D000312:Adrenal Hyperplasia, Congenital / Q000188:drug therapy*; D000818:Animals; D005438:Fludrocortisone / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D013607:Tablets
chemical_list: D013607:Tablets; D005438:Fludrocortisone