NADPH-d (dihydronicotinamide adenine dinucleotide phosphate diaphorase) activity in geniculo-tectal neurons of the rat.
Retrograde transport of horseradish peroxidase (HRP) and dihydronicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) histochemistry were used in order to determine whether NADPH-d-positive neurons of the ventral lateral geniculate nucleus (LGv) project to the superior colliculus (SC). Our results show that intensely stained NADPH-d neurons are restricted to the lateral half of the magnocellular division of LGv (LGv-MC), where they represent 50% of the total number of retrogradely labeled neurons. These findings indicate: (1) that LGv provides an important NADPH-d input to SC, and (2) that within the population of geniculo-tectal neurons, which constitute a morphologically well defined neuronal type, there are two different subclasses, one being NADPH-d positive and the other NADPH-d negative.
González-Hernández
T
T
Department of Anatomy, Faculty of Medicine, University of La Laguna, Tenerife, Spain.
Mantolán-Sarmiento
B
B
González-González
B
B
Ferres-Torres
R
R
Meyer
G
G
D000818:Animals; D005829:Geniculate Bodies / Q000166:cytology / Q000201:enzymology*; D006735:Horseradish Peroxidase; D009252:NADPH Dehydrogenase / Q000378:metabolism*; D009474:Neurons / Q000201:enzymology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013477:Superior Colliculi / Q000502:physiology; D009435:Synaptic Transmission; D003336:Tectum Mesencephali / Q000166:cytology / Q000201:enzymology*
D006735:Horseradish Peroxidase; D009252:NADPH Dehydrogenase