Chronic interstitial cystitis occurring during the shift between rheumatoid arthritis and lupus.
This case reports documents the progressive development of chronic interstitial cystitis during the overlapping process from rheumatoid arthritis to lupus. Concomitantly high titer antinuclear antibody with an anti-68 KD RNP pattern and other biological markers of lupus were observed in the blood. The symptoms dramatically improved under methotrexate therapy. The pathogenic mechanism is discussed.
Golstein
M A
MA
Division of Rheumatology, Erasmus University Hospital, University of Brussels.
Manto
M
M
Noel
J C
JC
Appelboom
T
T
D001172:Arthritis, Rheumatoid / Q000150:complications*; D001327:Autoimmune Diseases / Q000503:physiopathology; D002908:Chronic Disease; D003556:Cystitis / Q000188:drug therapy / Q000209:etiology / Q000276:immunology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000209:etiology*; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged
D008727:Methotrexate