title: Dominant lethals induced by Dithane M-45 in silkworm Bombyx mori.
abstract: Dithane M-45, a ethylenebis(dithiocarbamate) fungicide widely used in agriculture, including moriculture and sericulture, was tested for its efficacy in inducing dominant lethals in Bombyx mori. A polyvotine race of Pure Mysore was used for the studies and the topical application method was employed. After treatment with sublethal concentrations of 5, 10, and 20 g/50 larvae, the results have revealed that all of the concentrations could induce significant dominant lethals in a dose-dependent manner compared to controls. The results are discussed in the light of precautionary measures in the use of Dithane M-45 in the sericulture industry.
authors.affiliation: Department of Studies in Zoology, University of Mysore, India.
authors.forename: V
authors.initials: V
authors.lastname: Vasudev
authors.forename: G
authors.initials: G
authors.lastname: Subramanya
authors.forename: N B
authors.initials: NB
authors.lastname: Krishnamurthy
mesh_terms: D000818:Animals; D012831:Bombyx / Q000187:drug effects / Q000235:genetics* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D005260:Female; D007814:Larva / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D008297:Male; D008344:Maneb / Q000031:analogs & derivatives* / Q000633:toxicity; D009154:Mutation; D010058:Oviposition / Q000187:drug effects; D015038:Zineb / Q000031:analogs & derivatives* / Q000633:toxicity
chemical_list: D008344:Maneb; C011453:dithane M-45; D015038:Zineb