title: [Biomechanical pump as a cardiac assist and replacement system--the trend of research and development].
abstract: The trend of research and development of biomechanical pump (BMP) reviewed and two BMPs were presented. One was the BMP, consisting of a skeletal muscle ventricle, lined with a bioartificial endocardium. It consisted of a structural matrix made of a polyurethane porous membrane, fragmented blood vessels and collagen gel. In vitro and in vivo construction showed that this could provide biocompatibility. Another BMP is the system actuated by in situ latissimus dorsi muscle (LDM). Bellows were mounted on the back of the pump. The force of LDM contraction was transmitted through cables to the bellows resulting in blood ejection. To assist the pump filling and LDM re-extension, an additional force was incorporated to the pump. The prototype system showed good performance.
authors.affiliation: National Cardiovascular Center Research Institute.
authors.forename: T
authors.initials: T
authors.lastname: Nakatani
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D004558:Electric Stimulation; D004699:Endocardium; D006331:Heart Diseases / Q000628:therapy; D006353:Heart-Assist Devices; D006801:Humans; D008567:Membranes, Artificial; D009132:Muscles
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial