title: [Experimental model of induction in the rat of rapidly developing biliary cirrhosis in peripartal nodular cirrhosis].
abstract: The treatment with CCl4 and progesterone subsequent the common biliary duct ligature induced, in the rat, after 4-5 weeks, a cirrhotic picture characterized by an early and strong biliary epithelium proliferation followed by a perilobular fibrosis with a concentric sclerosis as in true perilobular cirrhosis.
authors.affiliation: Istituto di Patologia generale, Università degli Studi di Genova.
authors.forename: A
authors.initials: A
authors.lastname: Novelli
authors.forename: G R
authors.initials: GR
authors.lastname: Gambella
authors.forename: E
authors.initials: E
authors.lastname: Anselmo
authors.forename: G
authors.initials: G
authors.lastname: Nanni
mesh_terms: D000818:Animals; D001284:Atrophy; D002251:Carbon Tetrachloride / Q000633:toxicity*; D002455:Cell Division; D003135:Common Bile Duct; D004195:Disease Models, Animal; D005347:Fibroblasts / Q000473:pathology; D008026:Ligation; D008105:Liver Cirrhosis, Biliary / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D011374:Progesterone / Q000633:toxicity*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
chemical_list: D011374:Progesterone; D002251:Carbon Tetrachloride
vernacular_title: Modello sperimentale di induzione nel ratto di una cirrosi biliare a rapida evoluzione in cirrosi nodulare periportale.