Effectiveness of vitamin E for treatment of long-term tardive dyskinesia.
Eleven patients with tardive dyskinesia were treated in a double-blind study of vitamin E or placebo for 12 weeks. Abnormal Involuntary Movement Scale (AIMS) ratings were performed before and after treatment. Patients receiving vitamin E showed a significant reduction in their AIMS scale score, but patients receiving placebo showed no significant change. Vitamin E had a helpful effect even for patients whose tardive dyskinesia was mild and long-term.
Dabiri
L M
LM
Department of Psychiatry, San Mateo County Mental Health Services, Calif.
Pasta
D
D
Darby
J K
JK
Mosbacher
D
D
D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D004311:Double-Blind Method; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010808:Physical Examination; D010919:Placebos; D012720:Severity of Illness Index; D014810:Vitamin E / Q000627:therapeutic use*
D010919:Placebos; D014810:Vitamin E