Assessment of regional left ventricular long-axis motion with MR velocity mapping in healthy subjects.
The pattern of left ventricular long-axis motion during early diastole was assessed with magnetic resonance (MR) velocity mapping in 31 healthy volunteers. Regional long-axis velocity varied with time and position around the ventricle. During systole, the base descended toward the apex. The greatest magnitude of long-axis velocity occurred during early diastole. The lateral wall had the highest velocity (140 mm/sec +/- 40 [mean +/- standard deviation]); the anterior and inferior walls had lower velocities (96 mm/sec +/- 27 and 92 mm/sec +/- 34, respectively). The inferoseptal area consistently had the lowest velocities (87 mm/sec +/- 40). Absolute values of peak early-diastolic velocity declined with age (r = -.64, P < .001). Peak early-diastolic velocity was not dependent on heart rate (r = .014, P = .94). Regional variations in left ventricular wall motion were seen. MR velocity mapping is a useful technique for assessing regional left ventricular long-axis heart function.
Karwatowski
S P
SP
Royal Brompton National Heart and Lung Hospital, London, England.
Mohiaddin
R
R
Yang
G Z
GZ
Firmin
D N
DN
Sutton
M S
MS
Underwood
S R
SR
Longmore
D B
DB
D000328:Adult; D000368:Aged; D003971:Diastole / Q000502:physiology*; D005069:Evaluation Studies as Topic; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009040:Motion Pictures; D009200:Myocardial Contraction / Q000502:physiology; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*