title: Extrafascial hyper-reduction of the hepatic graft.
abstract: The technique and limits of graft reduction in orthotopic liver transplantation (OLT) are not well-defined, especially for small recipients. To reduce the hepatic graft to the left lateral segment (segments II and III), the authors have used an extrafascial hepatectomy without any dissection of the hepatic hilum. Among 165 pediatric OLT, 22 procedures using such hyper-reduced hepatic grafts were performed upon 21 children of median age 2.6 years between 1988 and 1992. These 22 hyper-reduced hepatic grafts were transplanted orthotopically with conservation of the inferior vena cava of the recipient. The three-year patient survival rate was 66 percent (80 and 50 percent for those patients undergoing elective and emergent procedures, respectively). The main postoperative complications were: primary graft nonfunction (n = 1), arterial complications (n = 2), portal vein thrombosis (n = 1), intra-abdominal bleeding (n = 2) and biliary complications (n = 2). This technique is useful in instances of a large size discrepancy between the donor and recipient. However, it does not increase per se the absolute number of hepatic grafts available for transplantation.
authors.affiliation: Clinique Chirurgicale, Hôpital Cochin, Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Soubrane
authors.forename: D
authors.initials: D
authors.lastname: Houssin
authors.forename: J
authors.initials: J
authors.lastname: Pitre
authors.forename: B
authors.initials: B
authors.lastname: Dousset
authors.forename: O
authors.initials: O
authors.lastname: Bernard
authors.forename: Y
authors.initials: Y
authors.lastname: Chapuis
mesh_terms: D000293:Adolescent; D002102:Cadaver; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D015996:Survival Rate