title: Escherichia coli K48 capsular polysaccharide: a glycan containing a novel diacetamido sugar.
abstract: The structure of the exocellular capsular polysaccharide expressed by Escherichia coli O8:K48:H9 has been investigated by hydrolysis and methylation analysis, and by NMR spectroscopic studies of the polysaccharide and of the oligosaccharides generated by solvolysis with anhydrous HF. The capsular polysaccharide was shown to have the repeating unit: [formula: see text] where beta-L-Sug p represents 2,3-diacetamido-2,3,6-trideoxy-beta-L- mannopyranose.
authors.affiliation: School of Pharmaceutical Sciences, Rhodes University, Grahamstown, South Africa.
authors.forename: D V
authors.initials: DV
authors.lastname: Whittaker
authors.forename: L A
authors.initials: LA
authors.lastname: Parolis
authors.forename: H
authors.initials: H
authors.lastname: Parolis
mesh_terms: D000942:Antigens, Bacterial; D000954:Antigens, Surface / Q000737:chemistry*; D016667:Bacterial Capsules; D002240:Carbohydrate Sequence; D004926:Escherichia coli / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D011135:Polysaccharides, Bacterial / Q000737:chemistry*; D017421:Sequence Analysis; D013237:Stereoisomerism
chemical_list: D000942:Antigens, Bacterial; D000954:Antigens, Surface; C030659:K antigens; C087304:K48 capsular polysaccharide, Escherichia coli; D011135:Polysaccharides, Bacterial