title: Update on lithium carbonate therapy in children and adolescents.
abstract: The use of lithium to treat child and adolescent psychiatric disorders is becoming more common. Since the publication of the report of The Committee on Biological Aspects of Child Psychiatry of the American Academy of Child Psychiatry in 1978, a considerable body of literature has accumulated on the efficacy of lithium in treating adolescent bipolar disorders, childhood aggression, and behavioral disorders associated with mental retardation and developmental disorders. Efforts to understand lithium's mechanism(s) and refinements in psychiatric diagnosis have contributed to its growing use.
authors.affiliation: University of Michigan Medical Center, Department of Psychiatry, Ann Arbor 48109-0290.
authors.forename: N
authors.initials: N
authors.lastname: Alessi
authors.forename: M W
authors.initials: MW
authors.lastname: Naylor
authors.forename: M
authors.initials: M
authors.lastname: Ghaziuddin
authors.forename: J K
authors.initials: JK
authors.lastname: Zubieta
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism; D000293:Adolescent; D000296:Adolescent Psychiatry; D002648:Child; D002665:Child Psychiatry; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D006801:Humans; D016651:Lithium Carbonate / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D001523:Mental Disorders / Q000145:classification / Q000188:drug therapy*; D010716:Phosphatidylinositols / Q000378:metabolism; D011954:Receptors, Dopamine / Q000187:drug effects; D011985:Receptors, Serotonin / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D010716:Phosphatidylinositols; D011954:Receptors, Dopamine; D011985:Receptors, Serotonin; D016651:Lithium Carbonate; D000262:Adenylyl Cyclases