Balanced 7;12 translocation associated with minimally differentiated acute myeloid leukemia.
A 4-year-old boy with leukemic blasts of myeloid lineage was shown by bone marrow (BM) examination to have a balanced 7;12 translocation. To our knowledge, this translocation in association with acute myeloid leukemia (AML) has not been reported previously.
Billson
A L
AL
Department of Child Health, University Hospital, Nottingham, England.
Latham
M
M
Jalihal
S
S
Martin
K
K
Walker
D A
DA
D000208:Acute Disease; D002675:Child, Preschool; D002881:Chromosomes, Human, Pair 12; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic / Q000235:genetics*