title: Astasia and gait failure with damage of the pontomesencephalic locomotor region.
abstract: Although there is evidence in experimental animals of the importance of the pedunculopontine area in locomotion, clinical lesion reports are lacking. An 83-year-old woman became unable to stand and to generate stepping movements after a hemorrhage at the pontomesencephalic junction involving the right pedunculopontine area. Her deficit resembled the gait failure present in some elderly individuals.
authors.affiliation: Department of Neurology, St Vincent's Hospital and Medical Center of New York, NY 10011.
authors.forename: J C
authors.initials: JC
authors.lastname: Masdeu
authors.forename: U
authors.initials: U
authors.lastname: Alampur
authors.forename: R
authors.initials: R
authors.lastname: Cavaliere
authors.forename: G
authors.initials: G
authors.lastname: Tavoulareas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005684:Gait / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008636:Mesencephalon; D009069:Movement Disorders / Q000209:etiology* / Q000503:physiopathology; D011149:Pons