title: Coincidental amyloid nephropathy and IgA glomerulonephritis in a patient with ankylosing spondylitis.
abstract: A 43-year-old man with ankylosing spondylitis (AS) was admitted with proteinuria and renal insufficiency. Coincidental IgA nephropathy and secondary renal amyloidosis were diagnosed on renal biopsy. This is the first case reported of coincidental IgA nephropathy and renal amyloidosis as a cause of renal insufficiency in a patient with AS. Both entities should be considered in the diagnosis in a patient with AS and renal impairment. A careful study of the renal tissue including, Congo red stain and immunofluorescence studies is necessary to establish a correct diagnosis in these patients.
authors.affiliation: Department of Rheumatology, Hospital Clínico i Provincial de Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Gratacós
authors.forename: A
authors.initials: A
authors.lastname: Collado
authors.forename: R
authors.initials: R
authors.lastname: Sanmartí
authors.forename: E
authors.initials: E
authors.lastname: Poch
authors.forename: A
authors.initials: A
authors.lastname: Torras
authors.forename: J
authors.initials: J
authors.lastname: Muñoz-Gomez
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D003224:Congo Red; D005455:Fluorescent Antibody Technique; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D007678:Kidney Glomerulus / Q000378:metabolism / Q000473:pathology; D008297:Male; D013167:Spondylitis, Ankylosing / Q000150:complications*
chemical_list: D003224:Congo Red