title: Assessment of the effect of ovarian suppressants on women with the premenstrual syndrome: iterative spectral analysis.
abstract: The daily mood symptoms of four women with the premenstrual syndrome (PMS) were recorded before, and after spontaneous or induced ovarian failure. Response was assessed by iterative spectral analysis and the results compared with techniques based on changes in the mean or median mood score, or the measurement of premenstrual tension in arbitrary 'menstrual' cycles. Only iterative spectral analysis had the capacity to establish the significance of a change in symptom cyclicity, an important attribute for a condition such as the PMS.
authors.affiliation: Department of Endocrinology, Christchurch School of Medicine, New Zealand.
authors.forename: M G
authors.initials: MG
authors.lastname: Metcalf
authors.forename: J H
authors.initials: JH
authors.lastname: Livesey
authors.forename: V
authors.initials: V
authors.lastname: Braiden
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects / Q000502:physiology; D005260:Female; D005583:Fourier Analysis; D012739:Gonadal Steroid Hormones / Q000097:blood; D017273:Goserelin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007044:Hysterectomy; D008593:Menopause / Q000502:physiology* / Q000523:psychology; D008597:Menstrual Cycle / Q000187:drug effects / Q000502:physiology / Q000523:psychology; D008875:Middle Aged; D010052:Ovariectomy; D011293:Premenstrual Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology
chemical_list: D012739:Gonadal Steroid Hormones; D017273:Goserelin