title: Childhood eczema: disease of the advantaged?
abstract: OBJECTIVE
  To determine whether the increased prevalence of childhood eczema in advantaged socioeconomic groups is due to increased parental reporting.
  
  
  METHODS
  Comparison of parental reports of eczema with visible eczema recorded by medical officers during a detailed physical examination.
  
  
  METHODS
  National birth cohort study.
  
  
  METHODS
  8279 children from England, Wales, and Scotland born during 3-9 March 1958 and followed up at the ages of 7, 11, and 16.
  
  
  METHODS
  Prevalence of eczema according to parental report compared with medical officer's examination at the ages of 7, 11, and 16.
  
  
  RESULTS
  Prevalence of both reported and examined eczema increased with rising social class at the ages of 7, 11, and 16 years. The point prevalence of examined eczema at age 7 was 4.8%, 3.6%, 3.6%, 2.4%, 2.2%, and 2.4% in social classes I, II, III non-manual, III manual, IV, and V respectively (chi 2 value for linear trend 12.6, P < 0.001). This trend persisted after adjustment for potential confounders such as region and family size and was not present for examined psoriasis or acne.
  
  
  CONCLUSIONS
  Eczema is more prevalent among British schoolchildren in social classes I and II than those in lower classes. Exposures associated with social class are probably at least as important as genetic factors in the expression of childhood eczema.
authors.affiliation: St John's Institute of Dermatology, United Medical School, Guy's Hospital, London.
authors.forename: H C
authors.initials: HC
authors.lastname: Williams
authors.forename: D P
authors.initials: DP
authors.lastname: Strachan
authors.forename: R J
authors.initials: RJ
authors.lastname: Hay
mesh_terms: D000293:Adolescent; D016009:Chi-Square Distribution; D002648:Child; D015331:Cohort Studies; D004485:Eczema / Q000453:epidemiology*; D005191:Family Characteristics; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D015995:Prevalence; D012111:Residence Characteristics; D012923:Social Class; D006113:United Kingdom / Q000453:epidemiology