title: Benign partial epilepsy with centrotemporal spikes: analysis of 94 Chinese children.
abstract: From October 1982 to June 1992, 94 neurologically normal Chinese Children (50 males & 44 females) with benign partial epilepsy of childhood with centrotemporal spikes were studied among 1847 epileptic infants and children. Their ages at onset were between 3.6 and 12 years (a mean of 7.3 years). All of them had normal birth and developmental histories. Seven patients (7.5%) had past history of febrile convulsion and 12 cases (12.8%) had family history of epilepsy. The depicted seizure patterns were protean, but most attacks (83%) occurred during sleep (nocturnal & diurnal). The duration of active period and seizure frequency had no significant difference in terms of sex and treatment, but early-onset patients (< 7.3 years) had statistically significant longer duration of active period than that of late-onset group (p < 0.01). We recommend that antiepileptic drug treatment is not essential for this disease. Even if antiepileptic drug is used, the low-dosed carbamazepine is suggested.
authors.affiliation: Department of Pediatrics, Taichung Veterans General Hospital, Taiwan, R.O.C.
authors.forename: W J
authors.initials: WJ
authors.lastname: Shian
authors.forename: C S
authors.initials: CS
authors.lastname: Chi
authors.forename: S C
authors.initials: SC
authors.lastname: Mak
authors.forename: C H
authors.initials: CH
authors.lastname: Chen
authors.forename: N Y
authors.initials: NY
authors.lastname: Hsu
mesh_terms: D002220:Carbamazepine / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D013624:Taiwan / Q000208:ethnology
chemical_list: D002220:Carbamazepine