title: [Effectiveness of the biospecific antiproteinase hemosorbent "Ovosorb" in the comprehensive treatment of diffuse suppurative peritonitis and acute destructive pancreatitis in dogs].
abstract: The authors examined the efficacy of the biospecific antiprotease hemosorption Ovosorb containing ovomucoid from duck egg protein as part of polyacrylamide gel, which was used in the multimodality treatment for experimental diffuse pyoperitoneum and acute destructive pancreatitis in dogs. Ovosorb effectively diminished proteasemia, restored the plasma inhibitory potential by eliminating dysproteinemia, suppressed the production of secondary peptide endotoxins. These effects of the hemosorbent promoted the regression of endotoxicosis and the significant reduction in experimental animal deaths.
authors.forename: N E
authors.initials: NE
authors.lastname: Filipovich
authors.forename: V V
authors.initials: VV
authors.lastname: Kirkovskiĭ
authors.forename: O F
authors.initials: OF
authors.lastname: Antiperovich
authors.forename: S B
authors.initials: SB
authors.lastname: Sinilo
authors.forename: G A
authors.initials: GA
authors.lastname: Lobacheva
mesh_terms: D000208:Acute Disease; D000818:Animals; D003131:Combined Modality Therapy; D004285:Dogs; D005260:Female; D008297:Male; D010059:Ovomucin / Q000627:therapeutic use*; D010195:Pancreatitis / Q000628:therapy*; D010538:Peritonitis / Q000628:therapy*; D011480:Protease Inhibitors / Q000627:therapeutic use*
chemical_list: D011480:Protease Inhibitors; C073841:Ovosorb; D010059:Ovomucin
vernacular_title: Effektivnost' biospetsificheskogo antiproteinaznogo gemosorbenta "Ovosorb" v kompleksnom lechenii razlitogo gnoĭnogo peritonita i ostrogo destruktivnogo pankreatita u sobak.