Genetic transformation of mycobacteria.
Recent advances in methods for introducing DNA into both fast- and slow-growing species of mycobacteria have stimulated the construction of a variety of cloning vectors and the development of a versatile genetic system. These tools will facilitate studies of mycobacterial pathogenicity, antibiotic action and drug resistance, and lead to more effective methods for diagnosis, prevention and treatment of mycobacterial diseases.
Hatfull
G F
GF
Dept of Biological Sciences, University of Pittsburgh, PA 15260.
D003227:Conjugation, Genetic; D009161:Mycobacterium / Q000235:genetics*; D010957:Plasmids; D014169:Transformation, Bacterial