[Acute postoperative pancreatitis].
The authors analysed 373 patients with acute pancreatitis which developed after operations on the organs of the pancreatoduodenal zone. Acute postoperative pancreatitis developed in 17.15% of cases after operations on the biliary tract, in 26.8% after resection of the stomach for ulcer, and in 51.47% of cases after resection of the stomach for carcinoma. A comparative evaluation of various methods for the prevention and treatment of acute postoperative pancreatitis (APP) is given, with appraisal of the traditional therapy (154 patients) without the use of protease inhibitors, and various methods of administration of protease inhibitors (135 patients) and cytostatics (84 patients). The mortality rate in progressive forms of APP was 25.2%, mortality being highest (30.4%) in treatment by the traditional methods including protease inhibitors and lowest in inclusion of cytostatics in the complex of therapeutic measures (7.1%).
Kulazhenkov
S A
SA
Anisimov
M A
MA
Fëdorov
V N
VN
Kuznetsov
E V
EV
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D011480:Protease Inhibitors / Q000627:therapeutic use*; D015996:Survival Rate
D000970:Antineoplastic Agents; D011480:Protease Inhibitors
Ostryĭ posleoperatsionnyĭ pankreatit.