title: Morphometrical histochemical and biochemical parameters in the dog alloxan diabetes.
abstract: Changes of morphometrical, biochemical, histochemical and immunohistochemical parameters were investigated in the alloxan diabetes in the dog. Samplings of material for electron microscopical and histochemical examinations were performed in 3 month period (4 times). A significant thickening of capillary basement membranes in the striated muscle (vastus lateralis) was ascertained even in the dog with glucose intolerance only. In this mentioned case a decrease of glucoso-6-phosphatase activity was observed. Evaluation of different types of muscle fibres assigned an increase of slow twitch fibres or intermediate ones respectively.
authors.affiliation: Institute of Histology and Embryology, 1st Medical Fac., Charles University, Praha, Czech Republik.
authors.forename: J
authors.initials: J
authors.lastname: Martínek
authors.forename: S
authors.initials: S
authors.lastname: Matolín
authors.forename: M
authors.initials: M
authors.lastname: Nozicková
authors.forename: V
authors.initials: V
authors.lastname: Bartos
authors.forename: Z
authors.initials: Z
authors.lastname: Lojda
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism / Q000473:pathology*; D004285:Dogs; D006651:Histocytochemistry; D008297:Male