[Change in the concentration of nontoxic plasma components in the process of hemosorption in experimental acute liver failure].
To study the hemosorption-induced changes in the plasma levels on nontoxic components, experiments were made on dogs with acute hepatic failure simulated by ligation of the common bile and vesicle tracts followed by administration of carbon tetrachloride into the common bile duct. Hemosorption was accomplished by the vein-vein variant by using KAU-type sorbent. Changes in lipid metabolism and the concentrations of biogenic amines were examined during and after a hemosorption session. The positive action of this procedure was found to appear as normalization of lipolysis whose activation occurred in acute hepatic failure, and as increases in the level of histamine and moderate-weight molecules.
Gutnikova
A R
AR
Alimov
M M
MM
Abidova
S S
SS
Kasymov
A Kh
AKh
D000818:Animals; D002251:Carbon Tetrachloride; D004285:Dogs; D006464:Hemoperfusion; D008026:Ligation; D017114:Liver Failure, Acute / Q000097:blood / Q000209:etiology / Q000628:therapy*
D002251:Carbon Tetrachloride
Izmenenie kontsentratsii netoksichnykh komponentov plazmy v protsesse gemosorbtsii pri éksperimental'noĭ ostroĭ pechenochnoĭ nedostatochnosti.