A technique for complete thymectomy in adult rats.
50 open thymectomies were performed in adult rodents using intubation combined with a fibrin glue able to prevent hemorrhage and pulmonary air leakage. This method had a 100% success rate and lower mortality than the ordinal suction procedure. Although the conventional suction thymectomy has been widely used, the open thymectomy method would permit more complete thymectomies for immunological studies.
Kobayashi
E
E
Department of Surgery, Omiya Medical Center, Jichi Medical School, Japan.
Kamada
N
N
Enosawa
S
S
Toyama
N
N
Delriviere
L
L
Goto
S
S
Lord
R
R
Stamatiou
S
S
Miyata
M
M
D000818:Animals; D005260:Female; D008297:Male; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D013934:Thymectomy / Q000379:methods*; D013950:Thymus Gland / Q000601:surgery*