title: [MR tomography and bone marrow scintigraphy in the screening of skeletal metastases in patients with breast carcinoma].
abstract: 46 patients with recently diagnosed carcinoma of the breast were included in a prospective comparative study of MRI and bone marrow scintigraphy. The aim of the study was to compare these procedures within a histologically unified patient collective. It was shown that MRI was superior to bone marrow scintigraphy in respect of sensitivity (92% vs 58%) and specificity (97% vs. 85%), although only about three quarters of the marrow spaces are examined by MRI screening. Bone marrow scintigraphy suffered particularly from a relatively high number of false positive findings (haemangiomas, degenerative changes). MRI remains the method of choice for investigating the bone marrow.
authors.affiliation: Radiologische Klinik, Universität Bonn.
authors.forename: G
authors.initials: G
authors.lastname: Layer
authors.forename: O
authors.initials: O
authors.lastname: Rieker
authors.forename: D
authors.initials: D
authors.lastname: Dörr
authors.forename: D
authors.initials: D
authors.lastname: Schnakenberg
authors.forename: A
authors.initials: A
authors.lastname: Steudel
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D001853:Bone Marrow / Q000000981:diagnostic imaging* / Q000473:pathology*; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000556:secondary*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D002277:Carcinoma / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D009367:Neoplasm Staging; D011446:Prospective Studies; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013669:Technetium Tc 99m Medronate; D014915:Whole-Body Counting / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data
chemical_list: D013669:Technetium Tc 99m Medronate
vernacular_title: MRT und Knochenmarkszintigraphie im Screening von Skelettmetastasen bei Patientinnen mit Mammakarzinom.