title: Pronounced differences in the frequency of TaqI beta A-inhibin alleles between sheep breeds with different reproductive performance.
abstract: A total of 419 individuals of four breeds with differing fecundity (Rhoenschaf, Merinolandschaf, East Friesian Milksheep, Romanov) and several wild sheep of the Ovis musimon, O. orientalis, O. vignei and O. ammon groups were screened for genetic variation at the beta A-inhibin (INHBA) locus with up to 11 enzymes. The four breeds differed significantly (P < 0.001) in TaqI allele frequencies. The frequency of the TaqI A allele coincided with the average litter size in each breed.
authors.affiliation: Institut für Tierzucht und Haustiergenetik, Justus-Liebig-Universitaet Giessen, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Leyhe
authors.forename: S
authors.initials: S
authors.lastname: Hiendleder
authors.forename: C
authors.initials: C
authors.lastname: Jaeger
authors.forename: R
authors.initials: R
authors.lastname: Wassmuth
mesh_terms: D000483:Alleles; D000818:Animals; D015252:Deoxyribonucleases, Type II Site-Specific; D005298:Fertility / Q000235:genetics*; D014644:Genetic Variation; D007265:Inhibins / Q000235:genetics*; D008098:Litter Size; D010455:Peptides / Q000235:genetics; D029584:Prostatic Secretory Proteins; D012756:Sheep / Q000235:genetics* / Q000502:physiology; D013045:Species Specificity
chemical_list: D010455:Peptides; D029584:Prostatic Secretory Proteins; C043076:beta-microseminoprotein; D007265:Inhibins; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases