title: The impact of patient's age on surgical therapy of colorectal liver metastases.
abstract: In a consecutive series of 90 hepatic resections for colorectal liver metastases which were performed during a 10-year period at one institution, the influence of patient's age on surgical strategies and postoperative results was investigated. The mean age of all patients was 61 +/- 11 years with a range from 27-78 years; 19 patients (21%) were younger than 50 years and 18 patients (20%) were older than 70 years. Thirty-six (40%) major and 54 (60%) minor hepatic resections were performed. The postoperative complication rate was 26% and resection mortality 3%. Estimated overall median survival time was 27 months, operative mortality included. 1-, 3-, and 5-year survival rates were 78%, 45%, and 32%, respectively. Although there is some suggestion that selection criteria are more aggressive in younger patients, neither surgical procedures nor postoperative results were found to be determined by the numeric age of the patient in a significant way.
authors.affiliation: Department of Surgery, University of Cologne, Germany.
authors.forename: H U
authors.initials: HU
authors.lastname: Zieren
authors.forename: J M
authors.initials: JM
authors.lastname: Müller
authors.forename: J
authors.initials: J
authors.lastname: Zieren
authors.forename: H
authors.initials: H
authors.lastname: Pichlmaier
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D000367:Age Factors; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D016019:Survival Analysis; D015996:Survival Rate