Familial occurrence of multiple cutaneous chondromas.
True cutaneous chondromas are rare lesions with an uncertain pathogenesis. We report an unusual case of a patient with multiple cutaneous chondromas of the face. One of the patient's siblings, a brother, and that brother's son had similar facial lesions. We conclude that this familial pattern suggests an autosomal dominant mode of transmission.
Humphreys
T R
TR
Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Herzberg
A J
AJ
Elenitsas
R
R
Johnson
B L
BL
Goldstein
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002467:Cell Nucleus / Q000648:ultrastructure; D018210:Chondromatosis / Q000235:genetics* / Q000473:pathology; D003593:Cytoplasm / Q000648:ultrastructure; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D009669:Nose Neoplasms / Q000235:genetics* / Q000473:pathology; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology