title: Natural resistance of opossum (Didelphis marsupialis) to the mapanare (Bothrops lanceolatus) snake venom.
abstract: The inactivation of local and general effects of the Mapanare (Bothrops lanceolatus) venom by Opossum's (Didelphis marsupialis) serum fractions was tested using an in vivo assay and an in vitro preincubation experiment. A serum fraction of the Opossum serum has been obtained by immunochemical purification. It is only present in opossum's protective opossum serum fraction (F-0.1).
authors.affiliation: Instituto de Medicina Tropical, Universidad Central de Venezuela.
authors.forename: F
authors.initials: F
authors.lastname: Pifano
authors.forename: I
authors.initials: I
authors.lastname: Aguilar
authors.forename: M E
authors.initials: ME
authors.lastname: Giron
authors.forename: N
authors.initials: N
authors.lastname: Gamboa
authors.forename: A
authors.initials: A
authors.lastname: Rodriguez-Acosta
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000032:analysis / Q000187:drug effects; D017837:Bothrops; D002848:Chromatography, DEAE-Cellulose / Q000379:methods; D002850:Chromatography, Gel / Q000379:methods; D003435:Crotalid Venoms / Q000037:antagonists & inhibitors* / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D004351:Drug Resistance; D006470:Hemorrhage / Q000097:blood / Q000139:chemically induced; D051379:Mice; D009893:Opossums / Q000097:blood*; D014687:Venezuela
chemical_list: D001798:Blood Proteins; D003435:Crotalid Venoms