[The morphological and immunohistochemical study of esophageal pseudosarcomatous and carcinosarcomas--report of 10 cases].
Twenty cases of esophageal carcinosarcoma were diagnosed and treated in this hospital during 1958-1990. Of which, 10 cases were reexamined by morphology and immunohistochemistry stained with 17 different antibodies. The results showed that: (1) There were 6 cases of true carcinosarcoma, 3 of pseudosarcoma and 1 case belonging to primary esophageal malignant fibrohistiocytoma; (2) In the cases of true carcinosarcoma, the tumor tissue displayed certain heterogeneity of carcinomatous and/or sarcomatous components, suggesting a potential for multi-directional differentiation; (3) It may be important that most of the tumors showed an intra-luminal or polypoid growth pattern and fewer metastasis, with a better prognosis. There are 6 surviving cases among 9 followed up over 2 years and the longest survivor has been up to 15 years.
Zhang
X
X
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D002296:Carcinosarcoma / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D011379:Prognosis