title: A comparison of stress-induced porosity due to conventional and a modified spinal fixation device.
abstract: A hypothesis that device-related osteopenia can be reduced by decreasing the rigidity of a fixation device was tested through a canine study. Polymer washers were interposed between the integral nut and plate of the variable spinal plating (VSP) system to reduce its rigidity. A solid fusion was observed 6 months postoperatively in all of the animals using VSP or modified systems. The stabilized segment using both systems showed similar load-displacement behaviors immediately after surgery and 6 months postoperatively. Although not significant, 5.6 and 1.8% decreases in volumetric density of mineralized bone were found in the stabilized segments due to VSP and modified systems, respectively. The modified system also increased bone growth around screws. The new concept of using polymer washers, to decrease rigidity of the fixation device over time, may reduce device-related osteopenia.
authors.affiliation: Department of Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee 53226.
authors.forename: T H
authors.initials: TH
authors.lastname: Lim
authors.forename: V K
authors.initials: VK
authors.lastname: Goel
authors.forename: J M
authors.initials: JM
authors.lastname: Winterbottom
authors.forename: B
authors.initials: B
authors.lastname: Kessler
authors.forename: J Y
authors.initials: JY
authors.lastname: Ahn
authors.forename: J K
authors.initials: JK
authors.lastname: Gwon
authors.forename: J B
authors.initials: JB
authors.lastname: Park
authors.forename: J N
authors.initials: JN
authors.lastname: Weinstein
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001851:Bone Diseases, Metabolic / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D001860:Bone Plates; D001863:Bone Screws; D002921:Cicatrix / Q000473:pathology; D004285:Dogs; D004577:Electron Probe Microanalysis; D004867:Equipment Design; D005260:Female; D016268:Internal Fixators / Q000009:adverse effects*; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery; D008297:Male; D016348:Osseointegration; D013123:Spinal Fusion / Q000295:instrumentation*; D013314:Stress, Mechanical; D014945:Wound Healing