Blocking of potassium channels in Ranvier nodes by 1,2,3,4,10-substituted acridin-9-ons and its possible significance on demyelinating diseases.
Bohuslavizki
K H
KH
Physiological Institute, University of Kiel, Germany.
Hänsel
W
W
Kneip
A
A
Koppenhöfer
E
E
Niemöller
E
E
D000166:Acridines / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D003711:Demyelinating Diseases / Q000188:drug therapy; D004594:Electrophysiology; D066298:In Vitro Techniques; D026902:Potassium Channel Blockers; D015221:Potassium Channels / Q000187:drug effects / Q000378:metabolism; D011901:Ranvier's Nodes / Q000187:drug effects* / Q000502:physiology; D012964:Sodium / Q000378:metabolism; D013329:Structure-Activity Relationship; D014982:Xenopus laevis
D000166:Acridines; D026902:Potassium Channel Blockers; D015221:Potassium Channels; D012964:Sodium