Myocardial perfusion and left ventricular function early after successful PTCA in 1-vessel coronary artery disease.
Myocardial perfusion (201TI-ECT) and contractile function (99mTc-ventriculography) were studied during exercise and rest 3 to 6 days after PTCA in 20 patients (11 with stable and 9 with unstable angina pectoris). All patients had single vessel disease and no previous myocardial infarction. During exercise after PTCA the ejection fraction increased for 3 to 5% and no regional wall motion abnormalities, ST-segment depression or perfusion defects occurred (with exception in one patient with very early restenosis). Therefore, perfusion and wall motion were completely normalized at rest and during exercise within days after technically successful PTCA even in patients with previously unstable angina pectoris. Pathological stress test results after this time should thus be attributed to other causes e.g. early restenosis, multivessel disease, false positive tests) and are not due to the specific situation early after PTCA.
Hoffmeister
H M
HM
Medizinische Klinik und Poliklinik, Abt. III, Universität Tübingen, FRG.
Kaiser
W
W
Hanke
H
H
Müller-Schauenburg
W
W
Karsch
K R
KR
Seipel
L
L
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000503:physiopathology / Q000628:therapy*; D000789:Angina, Unstable / Q000503:physiopathology / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D003326:Coronary Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016277:Ventricular Function, Left / Q000502:physiology*