MR findings of secondary hemochromatosis: transfusional vs erythropoietic.
OBJECTIVE
The aim of this study was to demonstrate the MR characteristics of secondary hemochromatosis (transfusional versus erythropoietic).


METHODS
Magnetic resonance images of five patients with transfusional (n = 3) or erythropoietic (n = 2) hemochromatosis were reviewed.


RESULTS
The liver of all patients had low signal intensity in all pulse sequences. The spleen had low signal intensity in all patients with transfusional iron overload, but normal signal intensity in erythropoietic hemochromatosis, which had similar MR findings to idiopathic hemochromatosis. However, the pancreas had variable signal intensity.


CONCLUSIONS
On MRI the signal intensity of the spleen may allow distinction between transfusional and erythropoietic hemochromatosis.
Yoon
D Y
DY
Department of Radiology, Seoul National University College of Medicine, Korea.
Choi
B I
BI
Han
J K
JK
Han
M C
MC
Park
M O
MO
Suh
S J
SJ
D000328:Adult; D000368:Aged; D001855:Bone Marrow Diseases / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D006432:Hemochromatosis / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008099:Liver / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology; D013154:Spleen / Q000473:pathology; D065227:Transfusion Reaction