title: Intracranial compliance in infants: evaluation with Doppler US.
abstract: OBJECTIVE
  To test graded fontanelle compression during Doppler ultrasound (US) scanning to identify and monitor infants with altered cranial compliance.
  
  
  METHODS
  An ophthalmodynamometer exerted pressure on the anterior fontanelle during Doppler US scanning of the middle cerebral artery. Sixty examinations were performed in 43 infants--13 full-term and 11 premature healthy control subjects, 10 with increased intracranial volume, and nine with suspected abnormal cranial compliance but without increased intracranial volume. Resistive index (RI) and angle-corrected time-averaged mean velocities (TAV) of blood flow were compared at three different pressures.
  
  
  RESULTS
  Baseline RI values in healthy full-term infants were significantly lower than in healthy premature infants and infants with abnormal compliance (P < .05). Values for healthy premature infants and infants with abnormal compliance were indistinguishable (P > .5). Neither RI nor TAV changed significantly in healthy infants, but both changed significantly with compression in infants with abnormal cranial compliance.
  
  
  CONCLUSIONS
  This procedure may be more useful than measurement of RI of the anterior cerebral artery alone to evaluate infants with altered cranial compliance.
authors.affiliation: Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21287.
authors.forename: G A
authors.initials: GA
authors.lastname: Taylor
authors.forename: M D
authors.initials: MD
authors.lastname: Phillips
authors.forename: R N
authors.initials: RN
authors.lastname: Ichord
authors.forename: B S
authors.initials: BS
authors.lastname: Carson
authors.forename: J A
authors.initials: JA
authors.lastname: Gates
authors.forename: C S
authors.initials: CS
authors.lastname: James
mesh_terms: D001927:Brain Diseases / Q000000981:diagnostic imaging*; D001929:Brain Edema / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D003187:Compliance; D004453:Echoencephalography; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging; D007427:Intracranial Pressure; D011312:Pressure; D012886:Skull / Q000503:physiopathology*