Two cases of de novo precursor B-cell acute lymphoblastic leukemia with t(14;18), but without cytogenetic evidence of an associated Burkitt's or Burkitt's variant translocation.
This study reports two cases of acute lymphoblastic leukemia of precursor B-cell type. The cases were associated with a t(14;18), but no evidence of a Burkitt's-type translocation was found. There was also no evidence of a preexisting follicular lymphoma. This cytogenetic variety of acute lymphoblastic leukemia has not been reported previously.
Collett
J M
JM
Department of Diagnostic Hematology, Royal Melbourne Hospital, Victoria, Australia.
Begley
C G
CG
Sammann
M E
ME
Garson
O M
OM
McGrath
K M
KM
D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D002883:Chromosomes, Human, Pair 14; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D014178:Translocation, Genetic