title: Granular cell tumors.
abstract: The skin and subcutaneous tissue and mucosae of the head and neck are areas of predilection for granular cell tumors. These often histogenetically enigmatic lesions have two principal clinicopathologic presentations: an infantile (congenital) epulis form of the gnathic gingiva and a noncongenital soft tissue and aerodigestive form. Recurrences of either form are largely attributable to marginal excision and, for all sites, approach 15%. A malignant granular cell tumor is recognized, but requires rigorous histologic confirmation.
authors.affiliation: Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: M
authors.initials: M
authors.lastname: Kershisnik
authors.forename: J G
authors.initials: JG
authors.lastname: Batsakis
authors.forename: B
authors.initials: B
authors.lastname: Mackay
mesh_terms: D000367:Age Factors; D003937:Diagnosis, Differential; D005260:Female; D016586:Granular Cell Tumor / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008247:Lysosomes / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D012737:Sex Factors; D015996:Survival Rate