[Dna damage induced by active oxygen species and its role in the carcinogenesis process].
Oxygen, a necessary element for the life of a cell is also the source of active state of oxygen including free radicals, which can induced damage to cellular DNA. The damage can result in deleterious biological consequences such as the initiation and promotion of cancer. In this paper the characterization of the DNA damage and molecular mechanisms causing this damage is presented.
Oliński
R
R
Katedra i Zakład Biochemii Klinicznej AM, Bydgoszczy.
D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D004249:DNA Damage / Q000235:genetics*; D004273:DNA, Neoplasm / Q000032:analysis*; D006801:Humans; D017382:Reactive Oxygen Species / Q000009:adverse effects*
D004273:DNA, Neoplasm; D017382:Reactive Oxygen Species
Uszkodzenie DNA indukowane działaniem aktywnych form tlenu i ich rola w procesie karcynogenezy.