Evaluation of the hormonal function and features of the ultrasound picture of transposed ovary in cervical cancer patients after surgery and pelvic irradiation.
Conventional surgical methods for treatment of invasive cervical cancer inevitably lead to castration. In young women premature cessation of ovarian function may lead to serious short term and long term complications. The preservation of ovarian function if possible is crucial to improving quality of life. 48 patients with Ia and Ib carcinoma of the cervix entered this study. All patients were treated by Wertheim's radical hysterectomy with ovarian transposition. Some of them had adjuvant radiotherapy. It appears that radical surgery even with postoperative brachytherapy has not had adverse effect on ovarian function. It has been found that depletion of ovarian function might be expected in patients treated by external beam irradiation if the distance between the upper margin of the inlet field and the transposed ovary was less than 3 cm. In 91% cases, in USG examinations distinct reduction of transposed ovary echostructure were found.
Bidziński
M
M
Department of Gynaecological Oncology, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.
Lemieszczuk
B
B
Zieliński
J
J
D000328:Adult; D001918:Brachytherapy / Q000009:adverse effects; D003131:Combined Modality Therapy; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D007986:Luteinizing Hormone / Q000097:blood; D010053:Ovary / Q000098:blood supply / Q000000981:diagnostic imaging / Q000378:metabolism / Q000528:radiation effects / Q000601:surgery*; D011374:Progesterone / Q000378:metabolism; D011832:Radiation Injuries / Q000517:prevention & control*; D011867:Radioisotope Teletherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*; D014463:Ultrasonography; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*
D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone