A new myosin I gene in Drosophila.
We have identified and cloned a new myosin-I cDNA, myosin 61F, from Drosophila melanogaster. The sequence of myosin 61F cDNA shows high similarity to vertebrate myosin-I sequences. Myosin 61F is most similar to bovine myosin Ib, showing 78% similarity and 63% identity. Myosin 61F is a single copy gene which maps to polytene region 61F, a genomic region with several potential myosin mutations. The identification of a myosin-I gene in Drosophila will allow genetic analysis of myosin-I function in a metazoan organism.
Cheney
C M
CM
Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110.
Kravit
N G
NG
Verbsky
J W
JW
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004330:Drosophila / Q000235:genetics*; D017344:Genes, Insect / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics*; D009218:Myosins / Q000235:genetics* / Q000276:immunology; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
D009218:Myosins