title: [Autologous transplantation of nasal mucosa after severe chemical and thermal eye burns].
abstract: BACKGROUND
  Extensive conjunctival scarring is common after severe chemical and thermal eye burns. There is often not enough healthy conjunctiva from the other eye available to correct the symblepharons, therefore other autologous tissues have to be transplanted.
  
  
  METHODS
  From February 1992 until March 1993 13 patients were treated with free nasal mucosal grafts from the inferior turbinates for reconstruction of the fornices. The newly created deep fornices were secured by a silicone band. In 3 patients an Illig plastic shell was used additionally. The surgical treatment was supplemented with an intensive treatment with topical corticosteroids to decrease the inflammatory reaction.
  
  
  RESULTS
  The patients were followed for an average of 7-18 months. The interval between the accident and the transplantation ranged from 2-26 months. In 10 patients a reconstruction of the fornices was achieved. In all patients, however, some slight scars could be observed. Postoperative Schirmertest was markedly improved. These results encourage us to plan a penetrating keratoplasty in 7 cases. 3 patients showed a recurrence of the symblepharon 2 months after the transplantation.
  
  
  CONCLUSIONS
  The nasal mucosa graft material is best suited for repair of extensive symblepharon. The advantages of this tissue are the availability of large pieces of mucosa and the transplantation of intraepithelial goblet-cells. Long-term effects are the improvement and stabilisation of the tear film.
authors.affiliation: Augenklinik der RWTH Aachen.
authors.forename: R
authors.initials: R
authors.lastname: Kuckelkorn
authors.forename: M
authors.initials: M
authors.lastname: Wenzel
authors.forename: J
authors.initials: J
authors.lastname: Lamprecht
authors.forename: B
authors.initials: B
authors.lastname: Böcking
authors.forename: M
authors.initials: M
authors.lastname: Reim
mesh_terms: D000293:Adolescent; D000328:Adult; D000869:Anterior Eye Segment / Q000293:injuries / Q000601:surgery; D002057:Burns, Chemical / Q000601:surgery*; D005126:Eye Burns / Q000139:chemically induced* / Q000601:surgery; D006801:Humans; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D009297:Nasal Mucosa / Q000637:transplantation*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology; D013536:Suture Techniques
vernacular_title: Autologe Nasenschleimhauttransplantation nach schwersten Verätzungen und Verbrennungen.