title: [Cross-reacting HLA antigens as a factor increasing the risk of childlessness in a family].
abstract: A comparative analysis of HLA phenotypes of fertile and infertile spouses revealed that among the infertile the sum of spouses showed compatibility in two or three HLA antigens. A detailed analysis also showed that 10 infertile couples exhibited identical and 2 antigens with a similar structure and function with so-called cross-reactions increasing the histocompatibility index to 75%. The significance of these facts for infertility risk factors is discussed.
authors.forename: T S
authors.initials: TS
authors.lastname: Montag
authors.forename: G N
authors.initials: GN
authors.lastname: Drannik
authors.forename: I I
authors.initials: II
authors.lastname: Gorpinchenko
authors.forename: L A
authors.initials: LA
authors.lastname: Bystrov
authors.forename: M N
authors.initials: MN
authors.lastname: Sokolova
authors.forename: S N
authors.initials: SN
authors.lastname: Vashchenko
mesh_terms: D003429:Cross Reactions / Q000276:immunology; D005260:Female; D005298:Fertility / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology*; D006650:Histocompatibility Testing; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology / Q000276:immunology*; D007248:Infertility, Male / Q000453:epidemiology / Q000276:immunology*; D008297:Male; D010641:Phenotype; D011379:Prognosis; D012307:Risk Factors
chemical_list: D006680:HLA Antigens
vernacular_title: Perekrestnoreagiruiushchie antigeny sistemy HLA kak fator, povyshaiushchiĭ risk bezdetnosti v sem'e.