Coexistent multiple myeloma and myelofibrosis.
Although the association of bone marrow fibrosis with plasma cell dyscrasias has already been described in several reports, the close relationship between these entities still remains unclear. In this report we describe a patient with clinical and pathologic findings which initially suggested a diagnosis of myelofibrosis, subsequently shown to be coexistent with multiple myeloma. Possible explanations for this association are discussed.
Pulsoni
A
A
Department of Human Biopathology, University La Sapienza, Rome, Italy.
Bianco
P
P
La Verde
G
G
Mecarocci
S
S
Petrucci
M T
MT
Torromeo
C
C
Avvisati
G
G
D001853:Bone Marrow / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology; D002999:Clone Cells / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006412:Hematopoietic Stem Cells / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis / Q000473:pathology; D014411:Neoplastic Stem Cells / Q000473:pathology; D011230:Precancerous Conditions; D055728:Primary Myelofibrosis / Q000473:pathology