title: Complete bilateral oculomotor palsy: the only clinical sign of subarachnoid hemorrhage in leukemia.
abstract: We report the original case of a patient with acute myelogenous leukemia who presented with a painless, complete bilateral oculomotor palsy during induction chemotherapy. Headache, signs of meningeal irritation or further neurological symptoms were absent throughout the course of illness. The CT revealed a subarachnoid hemorrhage (SAH). Within a day of the onset of symptoms, the oculomotor palsy subsided completely with no residual damage. To our knowledge, this is the first described case of SAH in leukemia with complete bilateral oculomotor palsy being the only clinical symptom. Furthermore, the spontaneous remission of this pathological condition is an extremely rare event.
authors.affiliation: Department of Neurology, University of Münster, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Papke
authors.forename: H
authors.initials: H
authors.lastname: Masur
authors.forename: A
authors.initials: A
authors.lastname: Martinez-Rubio
authors.forename: H
authors.initials: H
authors.lastname: Ostermann
authors.forename: G
authors.initials: G
authors.lastname: Schuierer
mesh_terms: D000368:Aged; D017542:Aneurysm, Ruptured / Q000150:complications / Q000503:physiopathology; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000503:physiopathology; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D013345:Subarachnoid Hemorrhage / Q000150:complications; D013921:Thrombocytopenia / Q000150:complications / Q000503:physiopathology; D014057:Tomography, X-Ray Computed