title: Anaerobic lung infections.
abstract: Aspiration is the leading cause of anaerobic lung infections. Risk factors for these infections include a depressed level of consciousness, a history of seizure, general anesthesia, central nervous system or neuromuscular disease, cerebrovascular accident, impaired swallowing and use of a tracheal or nasogastric tube. Clinical presentation includes fever, weight loss, malaise and cough productive of foul-smelling sputum. Diagnosis is based on radiographic findings, clinical features and a characteristic morphology of mixed flora on Gram stain of uncontaminated pulmonary specimens. The diagnosis is confirmed by isolation of organisms, usually polymicrobial, on culture. Treatment includes proper drainage, debridement of necrotic tissue and an antibiotic regimen (often initially empiric) with an agent active against anaerobic and aerobic organisms.
authors.affiliation: State University of New York Health Science Center, Brooklyn College of Medicine.
authors.forename: M T
authors.initials: MT
authors.lastname: Vincent
authors.forename: B S
authors.initials: BS
authors.lastname: Goldman
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000191:economics; D001421:Bacteria, Anaerobic; D001424:Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy* / Q000382:microbiology* / Q000503:physiopathology; D011015:Pneumonia, Aspiration / Q000188:drug therapy / Q000382:microbiology / Q000503:physiopathology; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents