title: Surgically treated adnexal masses in infancy, childhood, and adolescence.
abstract: OBJECTIVE
  We retrospectively evaluated the clinical presentation and histopathologic findings of benign and malignant adnexal masses in infants, children, and adolescents.
  
  
  METHODS
  Between 1955 and 1992, 486 patients (aged 7 days through 20 years) with adnexal masses were surgically evaluated.
  
  
  RESULTS
  Of 521 adnexal masses, 92% were benign, including 335 nonneoplastic and 144 of 186 (77%) neoplastic lesions. The frequency of ovarian malignancies correlated inversely with patient age. Germ cell, stromal, and epithelial malignancies accounted for 40%, 21%, and 33%, respectively, of the 42 cancers. Nonconcordance between preoperative and postoperative diagnoses was noted in 94 cases. The most common preoperative diagnosis necessitating reassignment was acute appendicitis. During the last decade of this study, ultrasonography and computed tomography missed no malignancies.
  
  
  CONCLUSIONS
  Physicians who care for young girls must be familiar with the differential diagnosis of adnexal masses to advise conservative management when appropriate and surgical intervention when necessary.
authors.affiliation: Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905.
authors.forename: J T
authors.initials: JT
authors.lastname: van Winter
authors.forename: P S
authors.initials: PS
authors.lastname: Simmons
authors.forename: K C
authors.initials: KC
authors.lastname: Podratz
mesh_terms: D000046:Academic Medical Centers; D000291:Adnexal Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008910:Minnesota; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies