Effects of a pyrethroid type II pesticide on conditioned behaviors of rats.
Our present work investigated the effect of fenvalerate, a pyrethroid type II pesticide, on conditioned behaviors of rats. Pre-training administration of the pesticide did not modify passive avoidance but decreased active avoidance responses and operant conditioned responses; pre-training or pre-test administration of fenvalerate induced a facilitatory effect on passive avoidance task; pre-training and/or pre-test treatments reduced active avoidance responses of rats which received the pesticide before test; and post-training treatments were not capable of modifying both active and passive avoidance responses. Increased emotionality produced by the action of fenvalerate on the sympatho-adrenal system could be responsible for the differences observed between active and passive avoidance responses.
Moniz
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Departamento de Patologia, Faculdade de Medicina Veterinaria e Zootecnia Universidade de Sao Paulo, Brazil.
Bernardi
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Spinosa
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HS
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects*; D003216:Conditioning, Operant / Q000187:drug effects; D004193:Discrimination Learning / Q000187:drug effects; D004924:Escape Reaction / Q000187:drug effects; D007858:Learning / Q000187:drug effects*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009570:Nitriles; D011722:Pyrethrins / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D012640:Seizures / Q000139:chemically induced
D009570:Nitriles; D011722:Pyrethrins; C017690:fenvalerate