title: Postpartum blues: relationship between not-protein bound steroid hormones in plasma and postpartum mood changes.
abstract: The relationship between non-bound steroid hormone levels in plasma and the occurrence of postpartum mood changes was investigated in 26 newly delivered mothers throughout the first 5 days postpartum. Studies with saliva samples had reported higher concentrations of 17 beta-estradiol and progesterone on the days of symptoms in women experiencing postpartum blues. As there had been a controversy as to how far saliva concentrations reflect free hormone levels in plasma, free hormone levels of 17 beta-estradiol and progesterone were determined in plasma using ultrafiltration. No significant difference concerning free hormone levels could be found between women with and without postpartum blues.
authors.affiliation: Department of Psychiatry, Wuerzburg University, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Heidrich
authors.forename: M
authors.initials: M
authors.lastname: Schleyer
authors.forename: H
authors.initials: H
authors.lastname: Spingler
authors.forename: P
authors.initials: P
authors.lastname: Albert
authors.forename: M
authors.initials: M
authors.lastname: Knoche
authors.forename: J
authors.initials: J
authors.lastname: Fritze
authors.forename: M
authors.initials: M
authors.lastname: Lanczik
mesh_terms: D000339:Affect / Q000502:physiology*; D001007:Anxiety / Q000097:blood / Q000175:diagnosis / Q000523:psychology; D003863:Depression / Q000097:blood* / Q000175:diagnosis / Q000523:psychology; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D015592:Immunoradiometric Assay; D010555:Personality Inventory; D011247:Pregnancy; D011374:Progesterone / Q000097:blood*; D011388:Prolactin / Q000097:blood*; D011485:Protein Binding / Q000502:physiology; D011644:Puerperal Disorders / Q000097:blood* / Q000175:diagnosis / Q000523:psychology; D011863:Radioimmunoassay; D012016:Reference Values; D012463:Saliva / Q000378:metabolism
chemical_list: D011374:Progesterone; D004958:Estradiol; D011388:Prolactin