title: [Role of endothelial activation in urticaria].
abstract: The endothelial cells, because of their privileged situation between the tissues and the vessels, play an important role in the inflammatory reaction. Expression of adhesion molecules (ELAM 1 especially) allows adhesion of circulating neutrophils to the epithelial cell and thus initiates the reaction. During the reactions of immediate hypersensitivity, the flow of leucocytes observed in the late phase is dependent on mastocytes, the recruitment being under the positive or negative influence of several cytokines.
authors.affiliation: Service de dermatologie, Hôpital Timone, Marseille.
authors.forename: C
authors.initials: C
authors.lastname: Mestre-Deharo
authors.forename: J
authors.initials: J
authors.lastname: Sayag
mesh_terms: D015815:Cell Adhesion Molecules / Q000502:physiology; D016207:Cytokines / Q000502:physiology; D004730:Endothelium, Vascular / Q000503:physiopathology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000503:physiopathology; D008407:Mast Cells / Q000502:physiology; D009504:Neutrophils / Q000502:physiology; D014581:Urticaria / Q000503:physiopathology*
chemical_list: D015815:Cell Adhesion Molecules; D016207:Cytokines
vernacular_title: Rôle de l'activation endothéliale dans l'urticaire.