title: Treatment and outcome of severe lower-limb ischaemia.
abstract: The overall outcome of severe lower-limb ischaemia in terms of limb salvage and mortality is poorly documented. A consecutive series of 232 severely ischaemic legs in 209 patients was therefore studied. An aggressive policy of revascularization has been pursued; this was attempted in 89 per cent of legs, with a primary amputation rate of 8 per cent. The perioperative 30-day limb salvage rate was 79 per cent with a patient mortality rate of 20 per cent. At 12 and 24 months the limb salvage rates were 74 and 71 per cent and patient survival rates 75 and 73 per cent respectively. To identify high-risk groups the effects on limb salvage and mortality of age, sex, presentation, diabetes and ankle systolic pressure of 50 mmHg or less were studied. Using life-table analysis, none of the preoperative risk factors had an effect on limb salvage and mortality. An aggressive policy of revascularization provides excellent results in the treatment of patients with severe leg ischaemia.
authors.affiliation: Department of Surgery, Leicester Royal Infirmary, UK.
authors.forename: R D
authors.initials: RD
authors.lastname: Sayers
authors.forename: M M
authors.initials: MM
authors.lastname: Thompson
authors.forename: T
authors.initials: T
authors.lastname: Hartshorne
authors.forename: J S
authors.initials: JS
authors.lastname: Budd
authors.forename: P R
authors.initials: PR
authors.lastname: Bell
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical; D000800:Angioplasty, Balloon; D001794:Blood Pressure; D003925:Diabetic Angiopathies / Q000601:surgery; D005260:Female; D006801:Humans; D007511:Ischemia / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome