title: [Contribution of antimyosin antibody myocardial scintigraphy in the diagnosis of acute myocarditis].
abstract: The authors report three cases of acute myocarditis: the first patient was a 23 year old woman treated for tuberculosis who presented with rapidly progressive congestive cardiac failure. The second patient was a 52 year old man with atypical chest pain and the third was a 55 year old woman presenting as an acute myocardial infarction. In all three cases, a positive antimyosin antibody myocardial scintigraphy supported the presumptive diagnosis. The authors review the principles of the method and its potential indications, antimyosin antibody scintigraphy being able to demonstrate recent myocardial necrosis but not to identify the cause. The sensitivity of the technique is high (83 to 100% according to the series) but the specificity is much lower (about 55%) compared with endomyocardial biopsy, an investigation which is specific but not very sensitive. Modifications of the antibody and the radioactive tracer used at present should improve the diagnostic value of the technique in the near future.
authors.affiliation: Service de médecine nucléaire, hôpital Avicenne, Bobigny.
authors.forename: P
authors.initials: P
authors.lastname: Weinmann
authors.forename: D
authors.initials: D
authors.lastname: Le Guludec
authors.forename: M
authors.initials: M
authors.lastname: Kebbou
authors.forename: S
authors.initials: S
authors.lastname: Bouton
authors.forename: J P
authors.initials: JP
authors.lastname: Maroni
authors.forename: M
authors.initials: M
authors.lastname: Namade
authors.forename: M
authors.initials: M
authors.lastname: Faraggi
authors.forename: J L
authors.initials: JL
authors.lastname: Moretti
mesh_terms: D000208:Acute Disease; D000328:Adult; D000911:Antibodies, Monoclonal; D001706:Biopsy; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D009218:Myosins / Q000276:immunology*; D011877:Radionuclide Imaging
chemical_list: D000911:Antibodies, Monoclonal; D009218:Myosins
vernacular_title: Apports de la scintigraphie myocardique aux anticorps anti-myosine dans le diagnostic des myocardites aiguës.