Escherichia coli producing CNF1 and CNF2 cytotoxins in animals with different disorders.
Two DNA probes were used for the detection of CNF1- and CNF2-positive E coli strains in a collection of 553 E coli isolates from cattle, sheep, goats, pigs, horses, dogs, cats and poultry. CNF-positive E coli were frequently associated with septicaemia in cattle, dogs, and cats, with diarrhoea in calves, cats and dogs, and with abortion in bovine and porcine species. CNF2-positive strains were observed among adult healthy cattle. They were also found in cases of pneumonia, metritis, mastitis in cattle and in 1 case of metritis of a mare. The physiopathology induced by CNF-positive E coli strains remains to be elucidated. However, the impact of CNF strains on veterinary pathology is clear and the diagnosis of CNF-producing E coli should become routine in veterinary practice.
Pohl
P
P
Institut National de Recherches Vétérinaires, Brussels, Belgium.
Oswald
E
E
Van Muylem
K
K
Jacquemin
E
E
Lintermans
P
P
Mainil
J
J
D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology*; D001427:Bacterial Toxins / Q000096:biosynthesis*; D002415:Cats; D002417:Cattle; D003603:Cytotoxins / Q000096:biosynthesis*; D015342:DNA Probes; D003670:Deer; D004285:Dogs; D004926:Escherichia coli / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D029968:Escherichia coli Proteins; D006041:Goats; D006736:Horses; D009693:Nucleic Acid Hybridization; D011200:Poultry; D012756:Sheep; D013552:Swine
D001427:Bacterial Toxins; D003603:Cytotoxins; D015342:DNA Probes; D029968:Escherichia coli Proteins; C060296:cytotoxic necrotizing factor type 1