Dermal toxicity of nickel and chromium in guinea pigs.
Liver and kidney enzyme activities and blood glucose and hemoglobin increased after 15 or 30 d of dermal exposure to nickel and chromium. Concentration of nickel and chromium increased in tissues. The changes were related to the duration of exposure.
Mathur
A K
AK
Industrial Toxicology Research Centre, Lucknow, India.
Gupta
B N
BN
D000279:Administration, Cutaneous; D000818:Animals; D002857:Chromium / Q000493:pharmacokinetics / Q000633:toxicity*; D004347:Drug Interactions; D006168:Guinea Pigs; D007668:Kidney / Q000187:drug effects* / Q000201:enzymology; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D009532:Nickel / Q000493:pharmacokinetics / Q000633:toxicity*; D012869:Skin Absorption
D002857:Chromium; D009532:Nickel