Immunity to Toxoplasma gondii.
Recent advances in our understanding of the immunological mechanisms involved during infection with Toxoplasma gondii include evidence for the role of different subsets of lymphocytes and cytokines in acute infection as well as in reactivation of chronic infection. The mechanisms of presentation of T. gondii antigen have been clarified recently, and animal models of toxoplasmosis that mimic disease observed in AIDS patients developed.
Subauste
C S
CS
Department of Immunology and Infectious Diseases, Palo Alto Medical Foundation, California 94301.
Remington
J S
JS
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology; D000818:Animals; D016207:Cytokines / Q000276:immunology; D003602:Cytotoxicity, Immunologic / Q000276:immunology; D006801:Humans; D007109:Immunity; D051379:Mice; D009061:Mouth Mucosa / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000276:immunology*; D014124:Toxoplasmosis, Animal / Q000276:immunology*
D016207:Cytokines