title: [Toxicity of levamisole in adjuvant chemotherapy for colorectal cancer].
abstract: We studied the levamisole toxic effects in adjuvant therapy for colorectal cancer. The therapy toxic effects on 127 patients were statistically more important in the levamisole-treated group compared to patients treated with folinic acid and 5-fluorouracil alone. Randomized studies in progress will demonstrate the real therapeutic value of levamisole.
authors.affiliation: Service de médecine interne-oncologie, hôpital Saint-Antoine, Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Navarro-Carola
authors.forename: A
authors.initials: A
authors.lastname: de Gramont
authors.forename: C
authors.initials: C
authors.lastname: Louvet
authors.forename: C
authors.initials: C
authors.lastname: Varette
authors.forename: B
authors.initials: B
authors.lastname: Demuynck
authors.forename: K
authors.initials: K
authors.lastname: Beerblock
authors.forename: D
authors.initials: D
authors.lastname: Soubrane
authors.forename: J D
authors.initials: JD
authors.lastname: Grangé
authors.forename: M
authors.initials: M
authors.lastname: Krulik
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D007978:Levamisole / Q000009:adverse effects* / Q000627:therapeutic use; D012189:Retrospective Studies
chemical_list: D007978:Levamisole; D002955:Leucovorin; D005472:Fluorouracil
vernacular_title: Toxicité du lévamisole dans la chimiothérapie adjuvante du cancer colorectal.