title: Management of non-palpable breast lesions detected mammographically.
abstract: A total of 212 consecutive fine-wire localization breast biopsies in 202 patients were performed on impalpable mammographically suspicious lesions. Preoperative fine-needle aspiration cytology was performed on 159 lesions and was valuable in planning the extent of the fine-wire localization biopsy. All 212 target lesions were accurately biopsied during the initial surgery. Overall, 134 lesions were malignant and 78 benign (benign:malignant ratio 1:1.72), with fewer biopsies for benign lesions performed in screened patients (benign:malignant ratio 1:2.43) than in those with symptoms (ratio 1:1). Breast conservation was achieved in 72 patients (80 per cent) with screen-detected in situ or invasive carcinoma and in 19 of 37 presenting via a symptomatic clinic. In 160 of 202 patients (79 per cent) the initial fine-wire localization biopsy was diagnostic and therapeutic.
authors.affiliation: Department of Surgery, North Tees General Hospital, Stockton-on-Tees, Cleveland, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Allen
authors.forename: W D
authors.initials: WD
authors.lastname: Thompson
authors.forename: R C
authors.initials: RC
authors.lastname: Stuart
authors.forename: P T
authors.initials: PT
authors.lastname: Gill
authors.forename: E W
authors.initials: EW
authors.lastname: Walton
authors.forename: K
authors.initials: K
authors.lastname: Karczenski
authors.forename: J
authors.initials: J
authors.lastname: Hoffman
authors.forename: A L
authors.initials: AL
authors.lastname: Peel
mesh_terms: D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D002278:Carcinoma in Situ / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000601:surgery; D018275:Carcinoma, Lobular / Q000601:surgery; D005260:Female; D006801:Humans; D008327:Mammography; D015413:Mastectomy, Simple; D008875:Middle Aged; D015641:Radiography, Interventional