title: [Proteolytic enzymes and their inhibitors].
abstract: Tryptase (T), chymase (C), carboxypeptidase A, cathepsin G-like constituent of preformed mediators contained in mastocyte granules, are a group of neutral proteases with proteolytic activity. These enzymes gives differentiation of two groups of mastocytes, MCTC and MCT as a function of the richness of enzymes. Although the functions of these molecules are becoming better and better understood, their exact roles as well as that of their inhibitors, still remain to be explored in urticaria.
authors.affiliation: CHU Timone Adultes, Service de Dermatologie Vénérologie, Marseille.
authors.forename: M C
authors.initials: MC
authors.lastname: Koeppel
authors.forename: J
authors.initials: J
authors.lastname: Sayag
mesh_terms: D000799:Angioedema / Q000201:enzymology; D002908:Chronic Disease; D053818:Chymases; D003594:Cytoplasmic Granules / Q000201:enzymology; D003876:Dermatitis, Atopic / Q000201:enzymology; D010450:Endopeptidases / Q000502:physiology; D008407:Mast Cells / Q000201:enzymology / Q000648:ultrastructure; D011480:Protease Inhibitors; D012697:Serine Endopeptidases / Q000502:physiology; D053802:Tryptases; D014581:Urticaria / Q000201:enzymology
chemical_list: D011480:Protease Inhibitors; D010450:Endopeptidases; D012697:Serine Endopeptidases; C083294:chymase 2; D053818:Chymases; D053802:Tryptases
vernacular_title: Enzymes protéolytiques et leurs inhibiteurs.