Hemoglobinopathies in the Dogon Country: presence of beta S, beta C, and delta A' genes.
The population of the Dogon, located in Mali, is divided in an endogamic Noble class and two endogamic servant castes (Tanners and Blacksmiths). We find that the polymorphic frequencies of beta c, beta S, and, unexpectedly, a mutation of the delta-chain (delta A'), are geographically (valley vs. plateau) as well as social status dependent.
Ducrocq
R
R
INED, Paris, France.
Bennani
M
M
Bellis
G
G
Baby
M
M
Traore
K
K
Nagel
R L
RL
Krishnamoorthy
R
R
Chaventre
A
A
D001483:Base Sequence; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006453:Hemoglobinopathies / Q000453:epidemiology* / Q000235:genetics; D006801:Humans; D008297:Male; D008302:Mali / Q000453:epidemiology; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012923:Social Class