title: Basaloid bronchial carcinoma. A histologic group with a poor prognosis.
abstract: BACKGROUND
  Basal cell carcinomas (BCCs) have been described in various locations, such as skin, anal canal, tongue, larynx, and recently, the lungs. These tumors seem to have a poor prognosis.
  
  
  METHODS
  A series of 115 surgically resected lung tumors, previously classified as poorly or undifferentiated carcinoma, were reviewed retrospectively. From these, 37 cases were reclassified as BCCs and were compared in terms of clinical features and survival, with 40 cases reclassified as poorly differentiated squamous cell (PDSC) carcinoma of the lung.
  
  
  RESULTS
  There was no difference between the groups regarding age, clinical presentation, pattern of relapse, and cause of death. Median and overall survival were different between the two groups, especially for Stage I and II patients: 5-year actuarial survival in the BCC group was 15% and in the PDSC group 47% (P = 0.004).
  
  
  CONCLUSIONS
  This subset of non-small cell lung cancer (NSCLC) has a worse prognosis than other NSCLC, and this should be considered in survival studies and new treatment trials.
authors.affiliation: Department of Respiratory Medicine, Hopital A. Michallon, Grenoble, France.
authors.forename: D
authors.initials: D
authors.lastname: Moro
authors.forename: P Y
authors.initials: PY
authors.lastname: Brichon
authors.forename: E
authors.initials: E
authors.lastname: Brambilla
authors.forename: D
authors.initials: D
authors.lastname: Veale
authors.forename: F
authors.initials: F
authors.lastname: Labat
authors.forename: C
authors.initials: C
authors.lastname: Brambilla
mesh_terms: D000328:Adult; D000368:Aged; D001984:Bronchial Neoplasms / Q000401:mortality* / Q000473:pathology*; D002280:Basal Cell Carcinoma / Q000401:mortality* / Q000473:pathology*; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality* / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology; D002423:Cause of Death; D005260:Female; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate