title: Clinical evaluation of Colgate Platinum Professional Toothwhitening System and Rembrandt Lighten Bleaching Gel.
abstract: A 2-week study was conducted to evaluate the tooth-whitening efficacy of Colgate Platinum Professional Toothwhitening System vs Rembrandt Lighten Bleaching Gel. Thirty-eight subjects completed this single-blind, randomized, parallel clinical study. The subjects were balanced into two groups based on a minimal shade of A3 on the Vita shade guide. The duration of product use was 30 minutes, twice daily for 2 weeks. Change in toodth color was measured by reflectance spectroscopy using a colorimeter. The readings were taken in the L*, a*, and b* color space at the initiation of the study, at 1 week, and at 2 weeks. Calculation of color change (deltaE) was performed using the color difference equation established by the Commission International de L'Eclairage. Results demonstated that Colgate Platinum was 46% more effective at tooth whitening after 1 week, and 96% more effective after 2 weeks of treatment. The results demonstrated that the Colgate product was significantly superior vs Rembrandt at increasing tooth whiteness (increase in deltaE), and tooth lightness (increase in deltaL*). No adverse reations were noted on clinical examination.
authors.forename: S A
authors.initials: SA
authors.lastname: Nathoo
authors.forename: M B
authors.initials: MB
authors.lastname: Chmielewski
authors.forename: K N
authors.initials: KN
authors.lastname: Rustogi
mesh_terms: D000704:Analysis of Variance; D000077463:Carbamide Peroxide; D003124:Colorimetry / Q000379:methods; D003188:Composite Resins / Q000627:therapeutic use*; D003742:Dental Devices, Home Care; D004338:Drug Combinations; D006801:Humans; D010545:Peroxides / Q000627:therapeutic use*; D019279:Resin Cements; D016037:Single-Blind Method; D014073:Tooth Bleaching; D014075:Tooth Discoloration / Q000628:therapy*; D014508:Urea / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D003188:Composite Resins; D004338:Drug Combinations; D010545:Peroxides; D019279:Resin Cements; D000077463:Carbamide Peroxide; C049160:Den-Mat; D014508:Urea