An evaluation of vesical urodynamics before renal transplantation and its effect on renal allograft function and survival.
This prospective study investigated the urodynamics of the urinary bladder prior to renal transplantation in 57 patients and related this to graft function and transplantation outcome. The study demonstrated a clear deterioration in the pretransplant urodynamic characteristics in all subgroups, with male patients in the hemodialysis group (HD) showing a more substantial decline: 1st sensation volume (ml) in male HD patients = 112 (120) vs. 171 (173) in male CAPD patients, P < 0.05; and corresponding average flow rate for same groups 3 (3) ml/sec vs. 5 (5) ml/sec, P < 0.05. Figures are median (interquartile range). We have identified a subgroup of patients with a small bladder capacity (less than 100 ml) who have a reduced graft survival (55% vs. 92% for bladders larger than 100 ml at 2 years) apparently unrelated to immunological processes.
Kashi
S H
SH
Academic Unit of Surgery, St. James's University Hospital, Leeds, United Kingdom.
Wynne
K S
KS
Sadek
S A
SA
Lodge
J P
JP
D000328:Adult; D005260:Female; D006085:Graft Survival; D006801:Humans; D007668:Kidney / Q000502:physiology; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D001743:Urinary Bladder / Q000502:physiology*; D014552:Urinary Tract Infections / Q000150:complications