Gemeprost in the management of second trimester intrauterine fetal death.
Gemeprost (Cervagem), a synthetic PGE1 prostaglandin analogue was used to induce labour in 20 patients with second trimester intra uterine fetal death. The mean induction abortion interval was 13.8 hours; 17 of the 20 patients delivered within 24 hours. In 17 cases the placenta was retained and the uterus was evacuated under general anaesthesia. Nausea was noted in five (25%) patients, vomiting in two (10%) and diarrhoea in three (15%). No serious side-effects were encountered.
Byrne
P
P
Department of Obstetrics and Gynaecology, Walsgrave Hospital, Coventry, UK.
Onyekwuluje
T
T
D000020:Abortifacient Agents, Nonsteroidal; D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D000527:Alprostadil / Q000031:analogs & derivatives*; D005260:Female; D005313:Fetal Death; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second
D000020:Abortifacient Agents, Nonsteroidal; C021182:gemeprost; D000527:Alprostadil