title: Use of the Gibbs sampler to estimate transition rates between grades of coronary disease following cardiac transplantation.
abstract: Coronary occlusive disease following cardiac transplantation is monitored using serial angiography, and graded on a 3 point scale according to the amount of narrowing observed in major vessels. Disease progression is modelled as a continuous time Markov process. The Gibbs sampler is used to estimate the marginal posterior distributions of the transition rates between grades of disease and from each grade to death.
authors.affiliation: MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, U.K.
authors.forename: L D
authors.initials: LD
authors.lastname: Sharples
mesh_terms: D000293:Adolescent; D000328:Adult; D000792:Angiography; D015982:Bias; D002648:Child; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008390:Markov Chains; D008875:Middle Aged; D011159:Population Surveillance; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D012494:Sampling Studies; D012720:Severity of Illness Index; D015996:Survival Rate; D013997:Time Factors