A methodological approach for integral assessment of the immune status.
The proposed approach for assessment of the immune status includes investigation of 21 immune indices of the three effector mechanisms of the immune system--the phagocytic activity, the cellular immunity and immunoregulatory cells and the humoral immunity. Standardized reference values for the corresponding immune indices were obtained using a statistical matrix. These values take into consideration the relationships between the immune reactions, thus allowing integral assessment of immune reactivity. This method permits diagnosis of immunodeficient conditions and control of immunocorrecting therapy. It also enables screening studies to be conducted on the immune status of subjects living in ecologically endangered regions.
Zlatev
S
S
Laboratory of Clinical Immunology, University of Medicine, Plovdiv, Bulgaria.
Dimitrov
I
I
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D006801:Humans; D007107:Immune System / Q000502:physiology*; D007111:Immunity, Cellular; D007159:Immunologic Tests / Q000706:statistics & numerical data; D007223:Infant; D010587:Phagocytosis; D012016:Reference Values