[The effect of translam on the natural resistance indices of the irradiated organism].
It has been studied the influence of translam-beta-1,3; 1,6-glucan, extracted from seaweed Laminaria, on the isolation of E. coli from spleen and on the functional activity of peritoneal macrophages of sublethal irradiated and infected mice. It has been shown the reduction of the number of microbes, isolated from spleen and stimulation of ingestive and digestive activity of macrophages following the introduction of translam in mice. This results show about the increase of natural resistance of irradiated organism under translam action and characterise this glucan as effective stimulator of immunity.
Kuznetsova
T A
TA
Krylova
N V
NV
Besednova
N N
NN
Vasil'eva
V N
VN
Zviagintseva
T N
TN
Krashevskiĭ
S V
SV
Eliakova
L A
LA
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D004353:Drug Evaluation, Preclinical; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000276:immunology; D005720:Gamma Rays; D005936:Glucans / Q000627:therapeutic use*; D007113:Immunity, Innate / Q000187:drug effects; D007795:Laminaria; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects; D011833:Radiation Injuries, Experimental / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D013997:Time Factors
D000276:Adjuvants, Immunologic; D005936:Glucans; D011837:Radiation-Protective Agents
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