title: Teflon granulomas and overinjection of Teflon: a therapeutic challenge for the otorhinolaryngologist.
abstract: We have found that Teflon granulomas and the overinjection of Teflon with the resulting laryngeal dysfunction, although uncommon, present a challenge to the otorhinolaryngologist, due in large part to the inflammatory reaction to the injected Teflon. This report addresses the management of 16 patients (12 women and 4 men) treated surgically for symptoms secondary to Teflon granulomas or vocal folds that had been overinjected with Teflon. The presenting symptoms varied and included airway obstruction, cough, choking, swallowing difficulties, and dysphonia. In each case the granuloma and Teflon were removed endoscopically via a lateral cordotomy. A second procedure to address dysphonia due to vocal cord lateralization was frequently required and presents the challenge for the surgeon to select the appropriate procedure and time of intervention. The results of this retrospective review suggest that resolution of inflammatory changes and fibrosis subsequent to Teflon removal requires significant lengths of time and that thyroplasty techniques provide a means for medialization without reintroduction of the original inflammatory material.
authors.affiliation: Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 55905.
authors.forename: J L
authors.initials: JL
authors.lastname: Kasperbauer
authors.forename: D H
authors.initials: DH
authors.lastname: Slavit
authors.forename: N E
authors.initials: NE
authors.lastname: Maragos
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000402:Airway Obstruction / Q000209:etiology; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene / Q000008:administration & dosage / Q000009:adverse effects*; D012189:Retrospective Studies; D014826:Vocal Cord Paralysis / Q000628:therapy; D014827:Vocal Cords / Q000601:surgery*; D014832:Voice Disorders / Q000209:etiology
chemical_list: D011138:Polytetrafluoroethylene