Use of the Gibbs sampler to estimate transition rates between grades of coronary disease following cardiac transplantation.
Coronary occlusive disease following cardiac transplantation is monitored using serial angiography, and graded on a 3 point scale according to the amount of narrowing observed in major vessels. Disease progression is modelled as a continuous time Markov process. The Gibbs sampler is used to estimate the marginal posterior distributions of the transition rates between grades of disease and from each grade to death.
Sharples
L D
LD
MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Cambridge, U.K.
D000293:Adolescent; D000328:Adult; D000792:Angiography; D015982:Bias; D002648:Child; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008390:Markov Chains; D008875:Middle Aged; D011159:Population Surveillance; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D012494:Sampling Studies; D012720:Severity of Illness Index; D015996:Survival Rate; D013997:Time Factors