[The effect of long-term adaptation to hypoxia on the open-field behavioral reactions in rats with different types of behavior].
We studied the influence of long-term (30 days) adaptation to hypobaric hypoxia (daily lifting to 5000 m for 5 h) on behaviour of rats with different typological characteristics and levels of resistance to hypoxia. Correlation was ascertained between the resistance of rats to oxygen deficiency and the open field locomotor activity. Adaptation was shown to induce the state of increased anxiety in animals of all the groups under study. In rats with the low resistance to hypoxia adaptation led to increase of exploratory activity. In rats with high initial resistance hypoxic influences caused an increased extinction of orienting reaction at repeated testing in the open field as well as motor excitation increase. In animals with active and medial types of behaviour hypoxic influences increased exploratory activity. In animals with the medial behavioural type increased exploratory activity was changed later by general motor excitation. In rats with the passive type of behaviour adaptation resulted in decrease of the number of rearings testifying to suppression of exploratory reactions, and in the phase changes of locomotor activity.
Livanova
L M
LM
Luk'ianova
L D
LD
Torshin
V I
VI
D000208:Acute Disease; D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D004198:Disease Susceptibility; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D051381:Rats; D013997:Time Factors
Vliianie dlitel'noĭ adaptatsii k gipoksii na povedencheskie reaktsii v otkrytom pole krys s raznym tipom povedeniia.