[Comparison of the effect of sijunzi decoction, siwu decoction and bazhen decoction on immune function in mice].
Sijunzi decoction, Siwu decoction and Bazhen decoction can antagonize the suppressive effect of hydrocortisone on proliferation of lymphocyte by spleen cells in C57BL/6J mice in vitro, and of the three decoctions Sijunzi works best. Sijunzi Decoction can antagonize the suppressive effect of cyclophosphamide on the delayed cutaneous hypersensitivity (DCH) induced by DNCB in mice and the production of hemolysin in mice immunized with SRBC. The three prescriptions all can enhance the clearance rate of iv charcoal particles as well as bone marrow cells inhibited by cyclophosphamide in mice, but Sijunzi decoction functions best of all.
Xu
A H
AH
Yangzhou Medical College.
Gong
Y X
YX
Gu
W R
WR
Wang
X W
XW
D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D001854:Bone Marrow Cells; D002452:Cell Count / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002606:Charcoal / Q000493:pharmacokinetics; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006460:Hemolysin Proteins / Q000096:biosynthesis; D006968:Hypersensitivity, Delayed / Q000188:drug therapy; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects; D051379:Mice
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal; D006460:Hemolysin Proteins; D002606:Charcoal