title: Clinical comparison of Colgate Platinum Toothwhitening System and Rembrandt Gel Plus.
abstract: A 2-week, three-cell study was conducted to evaluate the tooth-whitening efficacy of the Colgate Platinum Professional Toothwhitening System vs Rembrandt Gel Plus (a regimen of products consisting of a 10% carbamide peroxide gel, a whitening toothpaste, and a mouthrinse), and a placebo paste. Seventy subjects completed this parallel, single-blind, three-compartment, randomized clinical study. The subjects were balanced into two groups based on a minimal shade of A3 on the Vita shade guide and assigned a product. The duration of product usage was 1 hour twice daily for 2 weeks. Change in tooth color was measured by reflectance spectroscopy using a colorimeter. The readings were taken in the L*, a*, b* color space at the initiation, at 1 week, and at 2 weeks of the study. Calculation of color change (delta E) was performed using the color difference equation established by the Commission Internationale de L'Eclairage. Visual evaluation of shade changes was performed using the Vita shade guide. Results from this clinical study showed that Colgate Platinum was 77.7% more effective at tooth whitening after 1 week and 41.8% more effective after 2 weeks of treatment vs the Rembrandt regimen. Results showed that the Colgate product is significantly superior vs Rembrandt at increasing tooth whiteness (increase in delta E). Shade guide changes showed an overall improvement of 7.08 Vita tabs for the Colgate product and 5.12 Vita tabs for the Rembrandt regimen.
authors.affiliation: University of California, Los Angeles, School of Dentistry.
authors.forename: G M
authors.initials: GM
authors.lastname: Kowitz
authors.forename: S A
authors.initials: SA
authors.lastname: Nathoo
authors.forename: K N
authors.initials: KN
authors.lastname: Rustogi
authors.forename: M B
authors.initials: MB
authors.lastname: Chmielewski
authors.forename: L J
authors.initials: LJ
authors.lastname: Liang
authors.forename: R
authors.initials: R
authors.lastname: Wong
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000077463:Carbamide Peroxide; D003124:Colorimetry / Q000379:methods; D003188:Composite Resins / Q000627:therapeutic use*; D003742:Dental Devices, Home Care; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010545:Peroxides / Q000627:therapeutic use*; D019279:Resin Cements; D016037:Single-Blind Method; D013997:Time Factors; D014073:Tooth Bleaching / Q000379:methods*; D014075:Tooth Discoloration / Q000628:therapy*; D014508:Urea / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D003188:Composite Resins; D004338:Drug Combinations; D010545:Peroxides; D019279:Resin Cements; D000077463:Carbamide Peroxide; C049160:Den-Mat; D014508:Urea