Sex hormones in juvenile nasopharyngeal angiofibroma tissue.
Five cases of juvenile nasopharyngeal angiofibroma were studied in terms of the presence of progesterone, estradiol, testosterone, and dihydrotestosterone in the juvenile nasopharyngeal angiofibroma tissue using the peroxidase-antiperoxidase method. Progesterone and estradiol were positive in all cases. Testosterone was positive in 2 of the 5 patients. Dihydrotestosterone was positive in 3 of the 5 patients. Hormone in the juvenile nasopharyngeal angiofibroma tissue seems to change by the activity of nasopharyngeal angiofibroma.
Kumagami
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Department of Otolaryngology, School of Medicine, Nagasaki University, Japan.
D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005347:Fibroblasts / Q000187:drug effects / Q000648:ultrastructure; D005474:Fluoxymesterone / Q000008:administration & dosage / Q000627:therapeutic use; D005485:Flutamide / Q000008:administration & dosage / Q000627:therapeutic use; D012739:Gonadal Steroid Hormones / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000473:pathology*; D009367:Neoplasm Staging; D010784:Photomicrography; D012737:Sex Factors
D012739:Gonadal Steroid Hormones; D005485:Flutamide; D005474:Fluoxymesterone