Isolation of flavins from the Amazonian shrub Faramea guianesis.
In the pursuit of new leishmanicidal natural products, 5,7,4'-trihydroxyflavan [1] and the new product, 5,7-dihydroxy-4'-methoxyflavan [2], were isolated from the Guianian medicinal plant Faramea guianensis.
Sauvain
M
M
Institut Français de Recherche Scientifique pour le Développement en Coopération (ORSTOM), La Paz, Bolivia.
Dedet
J P
JP
Kunesch
N
N
Poisson
J
J
D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology; D005415:Flavins / Q000302:isolation & purification* / Q000494:pharmacology; D006172:Guyana; D007891:Leishmania / Q000187:drug effects; D007896:Leishmaniasis / Q000188:drug therapy; D008264:Macrophages / Q000187:drug effects / Q000469:parasitology; D051379:Mice; D008807:Mice, Inbred BALB C; D010946:Plants, Medicinal / Q000737:chemistry*
D000981:Antiprotozoal Agents; D005415:Flavins