title: [Possible origins of the gene of Hermansky-Pudlak in Puerto Rico].
abstract: Five out of six albino persons in Puerto Rico suffer from the Hermansky-Pudlak syndrome. This syndrome has been reported also in other countries such as Great Britain, the Netherlands, Belgium, and Mexico, among others. Due to the geographical isolation of the island it is likely that these patients share a common ancestor. In explaining how the gene may have arrived to Puerto Rico the following possibilities are considered: (1) British soldiers attacking the island since 1595. (2) Dutch attackers in 1625. (3) aboriginal tribes. (4) slave traders.
authors.affiliation: Centro de Enfermedades Hereditarias de la Visión de Johns Hopkins, Instituto Oftalmológico de Wilmer, Baltimore, Maryland.
authors.forename: N J
authors.initials: NJ
authors.lastname: Izquierdo
authors.forename: M A
authors.initials: MA
authors.lastname: Royuela
authors.forename: I H
authors.initials: IH
authors.lastname: Maumenee
mesh_terms: D016115:Albinism, Oculocutaneous / Q000235:genetics / Q000266:history*; D004739:England; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D006801:Humans; D009426:Netherlands; D011647:Puerto Rico
vernacular_title: Posibles vertientes del gene del síndrome de Hermansky-Pudlak en Puerto Rico.