Bronchodilator response to nebulized salbutamol in elderly patients with stable chronic airflow limitation.
The bronchodilator response to 5 mg nebulized salbutamol was studied in 20 elderly patients with stable chronic airflow limitation. Salbutamol produced significantly greater increases in FEV1 and FVC compared with placebo although there was no difference in subjective sensation of breathlessness. Spirometry can be successfully used to assess respiratory function in appropriately selected elderly patients with chronic airflow limitation.
Geraghty
R
R
King's College and Dulwich Hospitals, London, U.K.
Foster
C
C
Black
D
D
Roe
S
S
D000336:Aerosols; D000368:Aged; D000420:Albuterol / Q000008:administration & dosage* / Q000627:therapeutic use; D001980:Bronchi / Q000187:drug effects* / Q000502:physiology; D004311:Double-Blind Method; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D013147:Spirometry; D014797:Vital Capacity / Q000187:drug effects
D000336:Aerosols; D000420:Albuterol