title: Echocardiographic screening in neonates undergoing surgery for selected gastrointestinal malformations.
abstract: To compare echocardiography with clinical examination, radiography, and electrocardiography for the detection of congenital heart defects (CHD) a four year prospective study was carried out in 166 neonates with selected congenital gastrointestinal malformations (anorectal anomaly, tracheo-oesophageal fistula, duodenal atresia, exomphalos, and gastroschisis). Routine examination and investigation detected CHD in 16 neonates. Using echocardiography CHD was diagnosed in 38 (23%) neonates of whom five had two gastrointestinal malformations: in 22/57 (39%) with a tracheo-oesophageal fistula, 10/67 (15%) with an anorectal anomaly, 4/20 (20%) with exomphalos, 6/20 (30%) with duodenal atresia, and 1/7 with gastroschisis. A significantly higher incidence of CHD in neonates with gastrointestinal malformations was diagnosed using echocardiography (23%) compared with routine examination and investigation (9%). Early diagnosis of CHD allowed a unified approach to be presented to the family.
authors.affiliation: Department of Cardiology, Children's Hospital, Birmingham.
authors.forename: R M
authors.initials: RM
authors.lastname: Tulloh
authors.forename: S P
authors.initials: SP
authors.lastname: Tansey
authors.forename: K
authors.initials: K
authors.lastname: Parashar
authors.forename: J V
authors.initials: JV
authors.lastname: De Giovanni
authors.forename: J G
authors.initials: JG
authors.lastname: Wright
authors.forename: E D
authors.initials: ED
authors.lastname: Silove
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D004065:Digestive System Abnormalities; D004314:Down Syndrome / Q000150:complications; D004452:Echocardiography; D004562:Electrocardiography; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods*; D011446:Prospective Studies; D012680:Sensitivity and Specificity