title: [Lupus in children in Tunisia].
abstract: In this study, we have analyzed the clinical and serological features related to 16 Tunisian children in whom diagnosis of systemic lupus erythematosus was made before or at the age of 15. Renal involvement was found in 75% of cases and renal biopsies have mostly revealed severe histologic patterns. All of the patients who have been followed received corticosteroids and in some cases required additional cytotoxic drugs in order to control disease activity. Five children died in a context of a renal failure. This study of childhood lupus in Tunisia confirms that the clinical course of this disease in children is often aggressive.
authors.affiliation: Laboratoire d'immunologie, faculté de médecine, Tunis, Tunisie.
authors.forename: S
authors.initials: S
authors.lastname: Yalaoui
authors.forename: Y
authors.initials: Y
authors.lastname: Gorgi
authors.forename: S
authors.initials: S
authors.lastname: Meddeb
authors.forename: S
authors.initials: S
authors.lastname: Makni
authors.forename: R
authors.initials: R
authors.lastname: Lakhoua
authors.forename: A
authors.initials: A
authors.lastname: Debbabi
authors.forename: K
authors.initials: K
authors.lastname: Ayed
authors.forename: H
authors.initials: H
authors.lastname: Ben Maiz
authors.forename: M
authors.initials: M
authors.lastname: Hamza
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000453:epidemiology* / Q000276:immunology; D008181:Lupus Nephritis / Q000453:epidemiology / Q000209:etiology; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors
vernacular_title: Lupus de l'enfant en Tunisie.