title: [Conventional local intra-arterial fibrinolysis, spray lysis and mechanically accelerated fibrinolysis. An assessment of their position in the spectrum of angioplasty technics].
abstract: Intra-arterial local fibrinolysis was performed in 72 patients (51 men, 21 women, mean age 66.8 years) during the course of 78 angioplasties. 11.1% were stage IIa (Fontaine), 38.9% were stage II b, 27.8% were stage III and 22.2% were stage IV. The methods used were conventional fibrinolysis (15.4%), spray lysis (47.4%) and mechanically accelerated fibrinolysis (37.2%). In 66.7% the urokinase dose was < 600,000 I.U., in 17.9% it was > 1,000,000 I.U. Additional balloon dilatation was performed in 72 cases, percutaneous aspiration of thrombo-embolic material in 41 cases and stent implantation in 7 cases. Angiographically the procedure was successful in 90.7%; the Doppler index rose from 0.47 +/- 0.27 to 0.85 +/- 0.3 (p < 0.001). At discharge, staging was: I = 38.9%, IIa = 38.9%, IIb = 5.6%, III = 1.4%, IV = 15.3%. There were no systemic bleeding complications. In 5.1%, complications had to be treated surgically.
authors.affiliation: Abteilung Strahlendiagnostik des Medizinischen Zentrums für Radiologie, Philipps-Universität Marburg.
authors.forename: H J
authors.initials: HJ
authors.lastname: Wagner
authors.forename: E
authors.initials: E
authors.lastname: Starck
authors.forename: H
authors.initials: H
authors.lastname: Alfke
authors.forename: P
authors.initials: P
authors.lastname: Reuter
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D004359:Drug Therapy, Combination; D005069:Evaluation Studies as Topic; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007260:Infusion Pumps; D007261:Infusions, Intra-Arterial / Q000706:statistics & numerical data; D007269:Injections, Intra-Arterial / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015912:Thrombolytic Therapy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data
chemical_list: D005343:Fibrinolytic Agents
vernacular_title: Konventionelle lokale intraarterielle Fibrinolyse, Spraylyse und mechanisch akzelerierte Fibrinolyse. Standortbestimmung im Spektrum der Angioplastietechniken.