Hyperbaric oxygen therapy in calciphylaxis-induced skin necrosis in a peritoneal dialysis patient.
A 58-year-old white woman on continuous ambulatory peritoneal dialysis for 2 years developed calciphylaxis-induced necrotic skin lesions over both lower extremities. Despite subtotal parathyroidectomy and other conventional measures, skin lesions continued to worsen. Mapping of transcutaneous oxygen pressure showed markedly low values in involved areas. Skin ulcers completely healed after 38 sessions of hyperbaric oxygen therapy. The results in our case indicate that hyperbaric oxygen therapy may be useful in the treatment of skin ulcers secondary to calciphylaxis.
Vassa
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Division of Nephrology, University of Missouri Health Sciences Center, Columbia 65212.
Twardowski
Z J
ZJ
Campbell
J
J
D002115:Calciphylaxis / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008875:Middle Aged; D009336:Necrosis; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects; D012883:Skin Ulcer / Q000209:etiology / Q000473:pathology / Q000628:therapy*