[Changes of audio-vestibular parameters in experimental endolymphatic hydrops].
Endolymphatic hydrops were produced in twenty guinea pigs by obliteration of the endolymphatic sac. Auditory and vestibular functions were investigated before and after the obliteration. Our experimental data showed that: 1) the SPVN (sinusoidal pendular vestibular nystagmus) frequency decreased after the obliteration of the lymphatic sac; 2) the CAP response threshold to filtered clicks and the CAP response threshold to clicks were both elevated after obliteration of the endolymphatic sac; and 3) 2f1-f2 DPO (distortion product otoacoustic emissions) amplitudes, as induced by primary tones of adequate frequency and level rations, decreased as endolymphatic hydrops occurred.
Zhang
S Z
SZ
PLA General Hospital, Beijing.
D000818:Animals; D004584:Electronystagmography; D018159:Endolymphatic Hydrops / Q000503:physiopathology*; D005072:Evoked Potentials, Auditory; D005260:Female; D006168:Guinea Pigs; D009760:Nystagmus, Physiologic; D017084:Otoacoustic Emissions, Spontaneous; D014722:Vestibule, Labyrinth / Q000503:physiopathology*