beta 2-Microglobulin amyloidosis: illustrative cases.
Patients on long-term dialysis tend to develop amyloidosis derived from beta 2-microglobulin. Serum levels of this protein rise in renal insufficiency and remain high in patients on dialysis. The distribution of amyloid deposits in such patients as well as tissue diagnosis, immunohistochemistry, and electron microscopic features are briefly discussed.
Picken
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MM
Loyola University Medical Center, Maywood, Illinois 60153.
Shen
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D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis* / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D001613:beta 2-Microglobulin / Q000378:metabolism*
D001613:beta 2-Microglobulin