title: [Updating of relative data on tocopherols in clinical biochemistry].
abstract: The working group on lipophilic vitamins of the FSBC has reviewed current knowledge in the field of tocopherols and tried to summarize the most important and recent aspects that may be useful to clinical practitioners. The molecular structure of tocopherols and tocotrienols, their biogenesis, their analysis in foods, their metabolism in humans, their measurement in biological fluids, and the organism's needs and dietary requirements are reviewed. Their main functions as antioxidants and free radical scavengers are described at the molecular, ultra-structural, cellular and organ levels. The interest of these vitamins in three pathologies in which oxidative-stress has been implicated (atherosclerosis, cancer, kidney failure) is discussed.
authors.affiliation: Laboratoire de biochimie médicale A, université de Bordeaux II, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Artur
authors.forename: M J
authors.initials: MJ
authors.lastname: Cals
authors.forename: M
authors.initials: M
authors.lastname: Clerc
authors.forename: G
authors.initials: G
authors.lastname: Covi
authors.forename: A
authors.initials: A
authors.lastname: Crastes de Paulet
authors.forename: M
authors.initials: M
authors.lastname: Cruz-Pastor
authors.forename: B
authors.initials: B
authors.lastname: Herbeth
authors.forename: A
authors.initials: A
authors.lastname: Laschi-Loquerie
authors.forename: M
authors.initials: M
authors.lastname: Leclercq
authors.forename: J C
authors.initials: JC
authors.lastname: Mazière
mesh_terms: D001161:Arteriosclerosis / Q000378:metabolism; D002462:Cell Membrane / Q000502:physiology; D005260:Female; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology; D008099:Liver / Q000378:metabolism; D008297:Male; D009369:Neoplasms / Q000378:metabolism; D051437:Renal Insufficiency / Q000378:metabolism; D014810:Vitamin E / Q000737:chemistry / Q000378:metabolism*
chemical_list: D014810:Vitamin E
vernacular_title: Actualisation des données relatives aux tocophérols en biochimie clinique.