title: Diagnosis of diffuse lung disease by cutting needle biopsy.
abstract: The results of 15 consecutive automated cutting needle (1.2 mm, n = 14; 2.0 mm, n = 1) biopsies of diffuse lung manifestations are presented. Sufficient material for histologic analysis was obtained in 13 of 15 specimens (87%) and a specific diagnosis was obtained in 11 of 14 patients (79%). The tissue specimen confirmed the clinically probable lung disease in 6 patients, gave a new, unsuspected, diagnosis in 2, and resolved a differential diagnostic problem in 3 patients. One pneumothorax after a 2.0-mm needle biopsy necessitated catheter drainage. We conclude that percutaneous lung biopsy with the automated biopsy device mounted with a 1.2-mm needle yields a histologic diagnosis with high accuracy in interstitial and alveolar lung changes, reducing the need for more invasive methods such as open lung biopsy.
authors.affiliation: Department of Diagnostic Radiology, Kiljava Hospital, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Lohela
authors.forename: T
authors.initials: T
authors.lastname: Tikkakoski
authors.forename: K
authors.initials: K
authors.lastname: Ammälä
authors.forename: L
authors.initials: L
authors.lastname: Strengell
authors.forename: I
authors.initials: I
authors.lastname: Suramo
authors.forename: U K
authors.initials: UK
authors.lastname: Repo
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography