[Kapromed - antibacterial suture material].
The paper gives data on the composition and strength characteristics and experimental and clinical findings of resolving antimicrobial suture materials, such as Capromed-type one, based on the modified caproic fiber coated by the biocompatible polymer PPB-1 which contains antimicrobial drugs. Capromed threads are demonstrated to have high strength characteristics and resolve in the body within 8-9 months. Coating the modified caproic fibers with the biocompatible copolymer imparts them pseudomonfilament characteristics and prevents the penetration of cellular elements to the thickness of threads. The content of antibacterial agents in the polymer coating confers prolonged antibacterial properties on Capromed. Desorption of antimicrobial agents from Capromed is conducive to more favourable healing, prevents the development of ligature fistulas, favours an over 4-fold reduction in the incidence of wound complications, as compared to the controls.
Volenko
A V
AV
Germanovich
Ch S
ChS
Gurova
O P
OP
Shvets
R A
RA
D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control*; D001672:Biocompatible Materials; D004338:Drug Combinations; D004867:Equipment Design; D006801:Humans; D009757:Nylons; D011108:Polymers; D011183:Postoperative Complications / Q000517:prevention & control*; D011810:Quinoxalines / Q000627:therapeutic use*; D012995:Solubility; D013537:Sutures
D000890:Anti-Infective Agents; D001672:Biocompatible Materials; C060170:Capromed DC; D004338:Drug Combinations; D009757:Nylons; D011108:Polymers; D011810:Quinoxalines
Kapromed - antibakterialńyĭ shovnyĭ material.