title: Near infrared spectroscopy in adults. Does the Invos 3100 really measure intracerebral oxygenation?
abstract: Does the Invos near infrared spectroscopy monitor detect intracranial oxygenation, or reflect oxygenation of extracerebral tissues? The change in Invos regional cerebral oxygenation was studied during a doubling of middle cerebral artery flow with hypercapnia. There was no significant change in regional cerebral oxygenation, which suggests that the Invos does not reflect intracerebral oxygenation, possibly because of its narrow optode separation. The use of near infrared spectroscopy in adults may require a more powerful machine.
authors.affiliation: Department of Anaesthesia, Royal Postgraduate Medical School, Hammersmith Hospital, London.
authors.forename: D N
authors.initials: DN
authors.lastname: Harris
authors.forename: S M
authors.initials: SM
authors.lastname: Bailey
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D001783:Blood Flow Velocity; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry; D002245:Carbon Dioxide; D002536:Cerebral Arteries; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000032:analysis; D010101:Oxygen Consumption; D013055:Spectrophotometry, Infrared
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen