title: Multi-infarct dementia in Down's syndrome.
abstract: In spite of a burgeoning literature on the association of Down's syndrome with Alzheimer's disease, the occurrence of multi-infarct dementia has largely been overlooked. A 55-year-old woman with Down's syndrome in whom a dementing process was associated with evidence of significant cerebrovascular disease is reported here. It is considered that she sustained both multi-infarct dementia and probable Alzheimer's disease. It is suggested that such cases are under-reported.
authors.affiliation: Frith Hospital, Leicester, England.
authors.forename: R A
authors.initials: RA
authors.lastname: Collacott
authors.forename: S A
authors.initials: SA
authors.lastname: Cooper
authors.forename: I A
authors.initials: IA
authors.lastname: Ismail
mesh_terms: D001921:Brain / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000150:complications / Q000503:physiopathology; D015161:Dementia, Multi-Infarct / Q000150:complications* / Q000503:physiopathology; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged