title: The use of 13C n.m.r. and saturation transfer to detect tetrahedral intermediates in reactions catalysed by chymotrypsin and also in an amide inhibitor complex.
authors.affiliation: Department of Biochemistry, University College Dublin, Ireland.
authors.forename: T P
authors.initials: TP
authors.lastname: O'Connell
authors.forename: M D
authors.initials: MD
authors.lastname: Finucane
authors.forename: J P
authors.initials: JP
authors.lastname: Malthouse
mesh_terms: D001665:Binding Sites; D002247:Carbon Isotopes; D002918:Chymotrypsin / Q000737:chemistry / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D011480:Protease Inhibitors / Q000737:chemistry / Q000378:metabolism*; D012663:Semicarbazides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D002247:Carbon Isotopes; D011480:Protease Inhibitors; D012663:Semicarbazides; C087664:N-formylphenylalanine semicarbazide; D010649:Phenylalanine; D002918:Chymotrypsin