title: [The effectiveness of intravenous administration of large quantities of glucose in the treatment of bovine ketosis].
abstract: Glucose in a 40% (w/v) solution (200 g, 400 g or 600 g) was infused intravenously in clinically healthy cattle. On urinalysis, 13%, 19% and 26% respectively of the infused glucose was excreted. In cattle with elevated urinary ketone bodies, only the infusion of 400 or 600 g glucose led to a significant rise in the serum glucose concentration compared to initial values. Only the infusion of 600 g of glucose was followed by a significant decrease in serum beta-hydroxybutyrate 24 hours later compared to initial values. The present results indicate a possibility of improving the results of treatment of ketosis by infusion of high amounts of glucose.
authors.affiliation: Klinik für Klauentiere, Fortpflanzung und Haltungshygiene, Freien Universität Berlin.
authors.forename: M
authors.initials: M
authors.lastname: Metzner
authors.forename: W
authors.initials: W
authors.lastname: Hofmann
authors.forename: C
authors.initials: C
authors.lastname: Laiblin
mesh_terms: D020155:3-Hydroxybutyric Acid; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005947:Glucose / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006885:Hydroxybutyrates / Q000097:blood; D007262:Infusions, Intravenous / Q000662:veterinary; D007657:Ketone Bodies / Q000652:urine; D007662:Ketosis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D001786:Blood Glucose; D006885:Hydroxybutyrates; D007657:Ketone Bodies; D005947:Glucose; D020155:3-Hydroxybutyric Acid
vernacular_title: Untersuchungen zur Wirksamkeit intravenös verabreichter hoher Glukosemengen bei der Behandlung der Ketose des Rindes.