Complete heart block and torsade de pointes associated with thioridazine poisoning.
A 72-year-old woman attempted suicide with thioridazine 3000 mg and 60 tablets of acetaminophen 325 mg plus codeine 30 mg. She was semicomatose and had persistent third-degree atrioventricular block, progressive hypotension, and an episode of torsade de pointes. Heart block, arrhythmias, and hypotension resolved within 48 hours, and the patient recovered without adverse sequelae.
Hulisz
D T
DT
Akron General Medical Center, Department of Medicine, OH 44307.
Dasa
S L
SL
Black
L D
LD
Heiselman
D E
DE
D000368:Aged; D005260:Female; D006327:Heart Block / Q000139:chemically induced*; D006801:Humans; D013406:Suicide, Attempted; D013881:Thioridazine / Q000506:poisoning*; D016171:Torsades de Pointes / Q000139:chemically induced*
D013881:Thioridazine