title: [DNA flow cytometry of malignant melanoma of the choroid].
abstract: Thirty-five choroidal melanomas were analyzed by flow cytometry. DNA euploidy, aneuploidy and polyploidy were found in approximately 54, approximately 46, and approximately 20% of the tumors, respectively. No correlation between histological type and ploidy was found. The synthesis phase was irregular in approximately 25 and approximately 38% of the spindle and the mixed cell melanomas, respectively. The G2M peak was broadened in approximately 50% and in approximately 23% of the spindle and the mixed cell melanomas. About 20% of the malignant melanomas were highly proliferative. In 25% of the melanomas chemotherapy seemed to be useful.
authors.affiliation: Augenklinik Universität Leipzig.
authors.forename: M
authors.initials: M
authors.lastname: Fuchs
authors.forename: W
authors.initials: W
authors.lastname: Wohlrab
authors.forename: T
authors.initials: T
authors.lastname: Klapperstück
authors.forename: U
authors.initials: U
authors.lastname: Fuchs
mesh_terms: D001918:Brachytherapy; D002455:Cell Division / Q000502:physiology; D002829:Choroid / Q000473:pathology; D002830:Choroid Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D004273:DNA, Neoplasm / Q000032:analysis*; D015353:Eye Enucleation; D005434:Flow Cytometry; D016195:G2 Phase / Q000502:physiology; D006801:Humans; D008545:Melanoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D009367:Neoplasm Staging; D011003:Ploidies
chemical_list: D004273:DNA, Neoplasm
vernacular_title: DNS-Durchflusszytometrie maligner Melanome der Chorioidea.