title: [Microbiological study of nosocomial lung infections].
abstract: A total of 83 adult patients between 25 and 60 years of age who acquired pulmonary infectious disease within 48 hours after being admitted to the medical, surgical and/or intensive care units at the university hospital of the "Universidad de Los Andes" (Mérida, Venezuela) were studied during a period of 18 months. The most frequent clinical entity observed was pneumonia (49.4%). In all types of pulmonary samples obtained by secretion or puncture, more than half gave positive results to the microbiological analysis. Gram-negative bacilli prevailed as the etiological agents, with a preponderance of the species from Klebsiella (21.7%) and Pseudomonas (15.1%) genus. Staphylococcus aureus was also isolated in 13.3% of all cases. Satisfactory sensitivity to third generation cephalosporins and aminoglucosides was observed on these strains. Quinolones showed the highest antimicrobial activity. The application of an adequate antimicrobial therapy, according to the antibiotics sensitivity test results, allowed a successful clinical efficacy in 67.4% of all cases.
authors.affiliation: Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad de Los Andes, Mérida, Venezuela.
authors.forename: M C
authors.initials: MC
authors.lastname: Araque-Granadillo
authors.forename: B M
authors.initials: BM
authors.lastname: Nieves-Blanco
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D008169:Lung Abscess / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D016896:Treatment Outcome; D014687:Venezuela / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Estudio microbiológico de infecciones pulmonares de origen intrahospitalario.