title: Idiopathic, herpetic, and HIV-associated facial nerve palsies: abnormal MR enhancement patterns.
abstract: OBJECTIVE
  To determine specific criteria that can be used to define normal versus abnormal MR contrast enhancement of the facial nerve.
  
  
  METHODS
  Twenty-three patients with acute unilateral inflammatory peripheral facial nerve palsy were examined on a 1.5-T MR using multiplanar T1-weighted spin-echo sequences before and after injection of gadopentetate dimeglumine. These MR patterns were compared with those of healthy control subjects.
  
  
  RESULTS
  The normal facial nerve usually showed a mild to moderate enhancement of the geniculate ganglion and the tympanic-mastoid segment. The intracanalicular-labyrinthine segment did not enhance. All patients showed abnormal enhancement of the distal intracanalicular and the labyrinthine segment. An intense enhancement could be observed in the geniculate ganglion and the proximal tympanic segment, especially in herpetic palsy. Associated enhancement of the vestibulocochlear nerve was seen in herpetic and idiopathic palsy. Enhancement of the inner ear structures was detected only in herpetic palsy.
  
  
  CONCLUSIONS
  Abnormal contrast enhancement of the distal intracanalicular and the labyrinthine facial nerve segment is observed in all patients and is the only diagnostically reliable MR feature proving an inflammatory facial nerve lesion. The intense enhancement of the geniculate ganglion and the proximal tympanic segment is possibly correlated with the reactivation of the latent infection in the sensory ganglion. The abnormal enhancement results from breakdown of the blood-peripheral nerve barrier and/or from venous congestion in the venous plexuses of the epi- and perineurium.
authors.affiliation: Department of Neuroradiology, University Hospital of Zurich, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Sartoretti-Schefer
authors.forename: W
authors.initials: W
authors.lastname: Wichmann
authors.forename: A
authors.initials: A
authors.lastname: Valavanis
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005154:Facial Nerve / Q000033:anatomy & histology; D005158:Facial Paralysis / Q000209:etiology / Q000473:pathology*; D005260:Female; D016697:Herpes Zoster Oticus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies