title: [Chronic autoimmune type II hepatitis with various extrahepatic clinical manifestations].
abstract: We present the case of a patient with autoimmune chronic hepatitis and anti-LKM antibodies, who developed associated autoimmune diseases, cyclic nodose erythema, bilateral peripheric paralysis, idiopathic thrombocytopenic purpura and diabetes mellitus. We describe the first signs of the disease and how three different forms can be differentiated depending on the type of autoantibodies present in the patients' serum. Finally, we list several forms of presentation of the disease, the potential clinical associations with other autoimmune processes and the potential immunological basis for the development of the hepatic lesion.
authors.affiliation: Servicio de Medicina I., Hospital Universitario San Carlos, Ciudad Universitaria, Madrid.
authors.forename: J A
authors.initials: JA
authors.lastname: Colome Pavón
authors.forename: F
authors.initials: F
authors.lastname: Arranz García
authors.forename: M A
authors.initials: MA
authors.lastname: Viñuela Alejandre
authors.forename: D
authors.initials: D
authors.lastname: Espinos Pérez
mesh_terms: D001327:Autoimmune Diseases / Q000145:classification / Q000150:complications*; D002908:Chronic Disease; D006505:Hepatitis / Q000145:classification / Q000150:complications* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged
vernacular_title: Hepatitis crónica autoimmune tipo II con diversas manifestaciones clínicas extrahepáticas.