title: [Carcinoid tumor of the lung. An unusual form of ocular metastasis].
abstract: Carcinoid tumors are slowly and locally invasive growing neoplasms. Their main localization is in the ileum or in organs derived from the embryonic foregut, i.e. bronchus, stomach, pancreas and thyroid. The low rate of metastatic manifestation of about 10% indicates their potential malignancy. The endocrine effects vary. We describe the case of a 30-year-old female patient, who had had a carcinoid tumor of the bronchus with infiltration of a hilar lymph node, which had been resected two years previously. The postoperative course was marked by an increased level of urine 5-hydroxyindolacetic acid (5-HIAA). Finally, the patient complained a 4-month history of recurrent episodes of refractory conjunctival hyperemia, visual loss and visual field defects in both eyes. Examination revealed bilateral multiple choroidal masses associated with retinal detachment. As various authors have reported, carcinoid tumor metastases to the eye are extremely rare. Diagnostic approaches and therapeutic considerations are described. Ultrasonic examination of the choroidal lesion, applying standardized A-scan echography at tissue sensitivity, showed solid tissue masses and bilateral circumscribed exudative retinal detachment. The tumor was characterized by medium to high reflectivity and slight sound attenuation. The internal structure showed less irregularity than is usually seen in metastases.
authors.affiliation: Augenklinik, Technische Universität München, Klinikum rechts der Isar.
authors.forename: R
authors.initials: R
authors.lastname: Wertheimer
authors.forename: M
authors.initials: M
authors.lastname: Maier
authors.forename: H M
authors.initials: HM
authors.lastname: Hofmann
authors.forename: A
authors.initials: A
authors.lastname: Stanowsky
authors.forename: M
authors.initials: M
authors.lastname: Weiss
mesh_terms: D000328:Adult; D002276:Carcinoid Tumor / Q000473:pathology / Q000556:secondary*; D002829:Choroid / Q000473:pathology; D002830:Choroid Neoplasms / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000473:pathology
vernacular_title: Karzinoidtumor der Lunge. Eine ungewöhnliche Form der okulären Metastasierung.