title: Variation in quantitative respirator fit factors due to fluctuations in leak size during fit testing.
abstract: Variation in fit factors during quantitative respirator fit testing was studied for a high degree of fit (aerosol fit factors > 1000) and a low degree of fit (aerosol fit factors < 1000). In a controlled human study, fit factors were determined sequentially for three different exercises by (1) an aerosol fit test (using a portable condensation nuclei counter and room aerosol as the test agent) and (2) the newly developed dichotomous-flow fit test (Dichot). For the higher level of respirator fit, the aerosol fit factors were 30 to 60 times the corresponding flow fit factors, and for the lower level of respirator fit they were 2 to 4 times the flow fit factors. A coefficient of variation (CV) of 84% (GSD 1.6) for the higher respirator fit and 178% (GSD 2.2) for the lower respirator fit data was observed in the human study when aerosol fit factors for the three exercises were pooled. In a similar mannequin study, the center sampling probe gave aerosol fit factors with a CV of 5.4% (GSD 1.05). The flow fit factors for all three exercises pooled had a CV of 36% (GSD 1.3) for the higher respirator fit and 40% (GSD 1.5) for the lower respirator fit data, while the mannequin study gave flow fit factors with a CV of 2.2% (GSD 1.02). Thus, the variation in fit factors obtained in the human study was much higher than that obtained in a mannequin study. However, the variation in the aerosol method relative to the flow method, in the human study, os of the same order of magnitude as in the mannequin study.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Environmental Health, University of Cincinnati, OH 45267-0056.
authors.forename: U
authors.initials: U
authors.lastname: Krishnan
authors.forename: K
authors.initials: K
authors.lastname: Willeke
authors.forename: A
authors.initials: A
authors.lastname: Juozaitis
authors.forename: T
authors.initials: T
authors.lastname: Myojo
authors.forename: G
authors.initials: G
authors.lastname: Talaska
authors.forename: R
authors.initials: R
authors.lastname: Shukla
mesh_terms: D000388:Air / Q000032:analysis; D004867:Equipment Design; D006801:Humans; D011312:Pressure; D015203:Reproducibility of Results; D012134:Respiratory Protective Devices