TUBIS, a fossilized retroposon in the tubulin gene cluster of Trypanosoma brucei.
The genome of Trypanosoma brucei contains many copies of TRS/ingi, a retroposon like element of about 5 kb length. One vestigial member of this family, TUBIS, is found in the tubulin gene cluster. The element has sequence homologies to reverse transcriptase. The similarity to TRS/ingi is lost after 4 kb, resulting in a 3' truncated element. The sequence following downstream shows similarities to 5' flanking regions of VSG genes.
Glauser
A
A
Institute for General Microbiology, University of Bern, Switzerland.
Braun
R
R
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D017931:DNA Primers; D004251:DNA Transposable Elements; D016054:DNA, Protozoan; D008969:Molecular Sequence Data; D005810:Multigene Family; D016415:Sequence Alignment; D014346:Trypanosoma brucei brucei / Q000235:genetics*; D014404:Tubulin / Q000235:genetics*
D017931:DNA Primers; D004251:DNA Transposable Elements; D016054:DNA, Protozoan; D014404:Tubulin