[Cell culture in thyroid cancers].
The authors studied the diagnostic interest of cell cultures in thyroid tumors. They cultivated 10 tumours (4 papillary carcinomas, 5 medullary carcinomas and 1 sarcoma-looking tumour). In 7 cases, cultures yielded nothing more than pathologic examination. Nonetheless the study allowed to detect a double secretion (calcitonin and thyroglobulin) in 2 medullary carcinomas which turned out to be mixed proliferations. It also detected a production of thyroglobulin by the sarcoma. They think that cell cultures may have a diagnostic interest besides pathologic examination, allowing precise study of secretory features of the tumors.
Le Gall
F
F
Laboratoire d'Anatomie Pathologique B, Hopital Pontchaillou, CHR, Rennes.
Massart
C
C
Lucas
C
C
Le Clech
G
G
Bourdinière
J
J
Ramée
M P
MP
D000328:Adult; D000368:Aged; D002116:Calcitonin / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D013954:Thyroglobulin / Q000032:analysis; D013964:Thyroid Neoplasms / Q000378:metabolism / Q000473:pathology*; D014407:Tumor Cells, Cultured
D002116:Calcitonin; D013954:Thyroglobulin
Cultures cellulaires en carcinologie thyroïdienne.