Malignant hyperthermia and severe hypoglycemia after reexposure to halothane.
A four year child presented with an episode of malignant hyperthermia induced by reexposure to halothane. The episode was associated with early onset of a severe hypoglycemia and liver enzymatic perturbances. Etiology of these perturbances is hard to state precisely in this clinical context, but a hepatic toxicity of halothane and/or by dantrolene is considered.
Bichel
T
T
Department of Anesthesiology, University Hospital of Liege, C.H.U. B 35, Domaine Universitaire du Sart Tilman, Belgium.
Canivet
J L
JL
Damas
P
P
Lamy
M
M
D002675:Child, Preschool; D003620:Dantrolene / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006221:Halothane / Q000009:adverse effects*; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced* / Q000150:complications; D008099:Liver / Q000187:drug effects; D008305:Malignant Hyperthermia / Q000150:complications / Q000209:etiology*; D009301:Nasolacrimal Duct / Q000601:surgery
D003620:Dantrolene; D006221:Halothane