Short-term ibuprofen to prevent ossification after hip arthroplasty. No effects in a prospective randomized study of 47 arthrosis cases.
Heterotopic ossification after hip arthroplasty can be prevented by ibuprofen given 3 months postoperatively. To evaluate the effectiveness of 10 days of ibuprofen treatment we performed a randomized, double-blind, prospective study on 57 patients with primary arthrosis, undergoing total hip arthroplasty. 47 patients completed the study and no effect on the incidence of ossification could be detected.
Ahrengart
L
L
Department of Orthopedics, Karolinska Institute, Huddinge University Hospital, Sweden.
Blomgren
G
G
Törnkvist
H
H
D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D011182:Postoperative Care; D011446:Prospective Studies; D011859:Radiography
D007052:Ibuprofen