title: [Malignant pleural mesothelioma. A diagnostic and therapeutic challenge].
abstract: Malignant pleural mesothelioma is a tumor very difficult to diagnose and with a very controversial therapy. We describe an illustrative case with development of pleural overflow and detection of high adenosine-deaminase levels. Surgical resection combined with radiotherapy and/or chemotherapy is the current therapeutics. We describe the state-of-the-art advances in the immunohistochemical diagnosis and therapeutics and we stress the need to conduct cooperative studies in order to achieve a better knowledge of the prognosis factors, an effective step-by-step approach and innovative therapy strategies.
authors.affiliation: Servicio de Neumología, SCIAS, Hospital de Barcelona.
authors.forename: J L
authors.initials: JL
authors.lastname: Aliaga
authors.forename: A
authors.initials: A
authors.lastname: Román
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Buges
authors.forename: M
authors.initials: M
authors.lastname: Montane
authors.forename: X
authors.initials: X
authors.lastname: Puig
mesh_terms: D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D010994:Pleura / Q000473:pathology; D016066:Pleural Effusion, Malignant / Q000175:diagnosis / Q000628:therapy; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000628:therapy; D013902:Radiography, Thoracic
vernacular_title: Mesotelioma pleural maligno. Un desafío diagnóstico y terapéutico.