[The methods and results of simultaneous radiochemotherapy with carboplatin in advanced cervical carcinomas].
OBJECTIVE
The frequency and the poor therapeutic results in advanced cervical cancer establish the demand for effectiveness of treatment. Recent clinical data have shown that simultaneous radiochemotherapy may yield high remission rates in squamous cell carcinomas of other organs.


METHODS
In our Department of Radiotherapy and Radiooncology of the University of Leipzig we treated since 1.6.1991 17 patients with advanced cancer of the uterine cervix with a simultaneous radiochemotherapy with carboplatin.


RESULTS
The rate of complete remission was 76%. Follow-up is available from six to 24 months. Severe or toxic side effects of the treatment we didn't observe. Eight (47%) patients live relapse-free.


CONCLUSIONS
In our opinion randomized studies are required to determine: What is better? Simultaneous radiochemotherapy or radiotherapy?
Brock
A
A
Klinik für Strahlentherapie und Radioonkologie, Universität Leipzig.
Prager
W
W
Böhme
R
R
Pohlmann
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D016190:Carboplatin / Q000009:adverse effects / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011878:Radiotherapy / Q000009:adverse effects; D012074:Remission Induction; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*
D016190:Carboplatin
Methode und Ergebnisse der simultanen Radiochemotherapie mit Carboplatin bei fortgeschrittenen Zervixkarzinomen.