title: Prognostic factors in patients with nasopharyngeal carcinoma.
abstract: From 1971 to 1985 a total of 122 patients with non-distant metastatic nasopharyngeal carcinoma were treated at the Norwegian Radium Hospital with radiation doses that increased from 50 Gy (at 2 Gy/fractions) to 70 Gy (at 2 Gy/fractions) during the treatment period. Possible relationship between the increase in dose and survival time was investigated. The median cancer-specific survival time was 50 months, and the median crude survival time 38 months. No correlation was found between radiation dose and survival time. In a multivariate analysis histology was found to be the most important prognostic factor for survival with a relative risk of death from cancer of 3.4 and 3.2 for non-keratinizing carcinoma and squamous cell carcinoma respectively compared with undifferentiated carcinoma. When assessed in terms of N category the relative death risk for N2/N3 was 2.1 compared to N0/N1.
authors.affiliation: Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo.
authors.forename: S
authors.initials: S
authors.lastname: Kaasa
authors.forename: E
authors.initials: E
authors.lastname: Kragh-Jensen
authors.forename: K
authors.initials: K
authors.lastname: Bjordal
authors.forename: E
authors.initials: E
authors.lastname: Lund
authors.forename: J F
authors.initials: JF
authors.lastname: Evensen
authors.forename: H
authors.initials: H
authors.lastname: Vermund
authors.forename: O
authors.initials: O
authors.lastname: Monge
authors.forename: P
authors.initials: P
authors.lastname: Boehler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000401:mortality* / Q000532:radiotherapy*; D011379:Prognosis; D011879:Radiotherapy Dosage; D016019:Survival Analysis