title: Age-related changes in marrow distribution in the shoulder: MR imaging findings.
abstract: OBJECTIVE
  To define age-specific patterns of distribution of red and yellow marrow about the shoulder.
  
  
  METHODS
  Red and yellow marrow distribution was reviewed on magnetic resonance images of 189 subjects aged 15-69 years. Double-echo and fast spin-echo, gradient, and short inversion time inversion recovery pulse sequences were used. The acromion, glenoid, and proximal humeral epiphysis, metaphysis, and diaphysis in each shoulder were graded semiquantitatively and qualitatively.
  
  
  RESULTS
  There was a wide variation in the normal pattern of red-yellow marrow distribution both among subjects and among locations. All five anatomic locations showed an orderly progression from greater to lesser amounts of red marrow with increasing age. Many of the subjects had focal subchondral red marrow in the epiphysis, which was associated with patient age (P = .0001) and gender (P = .04).
  
  
  CONCLUSIONS
  Knowledge of normal patterns of marrow distribution can prevent their being misinterpreted as marrow-based disease.
authors.affiliation: Department of Radiology SB-05, University of Washington, Seattle 98195.
authors.forename: M L
authors.initials: ML
authors.lastname: Richardson
authors.forename: R M
authors.initials: RM
authors.lastname: Patten
mesh_terms: D000174:Acromion / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D006801:Humans; D006811:Humerus / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012782:Shoulder