title: Abnormal odontogenesis in children treated with radiation and chemotherapy: imaging findings.
abstract: Contemporary oncotherapy has improved survival of children with malignant diseases, but chemotherapy and radiotherapy also have deleterious effects. This essay illustrates the effects of chemotherapy and radiotherapy on dentition in children and adolescents. The illustrated abnormalities were seen on panoramic radiographs obtained before, during, and after treatment. Included are examples of hypodontia (partial anodontia), microdontia, altered eruption patterns, and root stunting. Comparison is made with normal dental development (Fig. 1).
authors.affiliation: Department of Radiology, University of Tennessee, Memphis 38103.
authors.forename: S C
authors.initials: SC
authors.lastname: Kaste
authors.forename: K P
authors.initials: KP
authors.lastname: Hopkins
authors.forename: J J
authors.initials: JJ
authors.lastname: Jenkins
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D009369:Neoplasms / Q000628:therapy; D009805:Odontogenesis / Q000187:drug effects* / Q000528:radiation effects*; D011862:Radiography, Panoramic; D011878:Radiotherapy / Q000009:adverse effects*; D014071:Tooth Abnormalities / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D000970:Antineoplastic Agents