Hypothalamic, striatal and plasma leucine enkephalin level in two rat models of portal hypertension.
In two rat models of portal hypertension obtained by common bile duct obstruction or by partial portal vein ligation the hypothalamic level of leu-enkephalin was increased but striatal and plasma level of leu-enkephalin was unchanged. These results may be of importance for understanding some disturbance related to hepatic encephalopathy.
Klin
M J
MJ
Department of Clinical Pharmacology, Medical Academy, Katowice, Poland.
Waluga
M
M
Madej
A
A
Plewka
A
A
Herman
Z S
ZS
D000818:Animals; D001663:Bilirubin / Q000097:blood; D003342:Corpus Striatum / Q000378:metabolism*; D004195:Disease Models, Animal; D004743:Enkephalin, Leucine / Q000032:analysis / Q000378:metabolism*; D006975:Hypertension, Portal / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism*; D008099:Liver / Q000473:pathology; D008297:Male; D009929:Organ Size; D011863:Radioimmunoassay; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000473:pathology
D004743:Enkephalin, Leucine; D001663:Bilirubin