title: Tolerability of combined treatment with lithium and fluoxetine: 14 cases treated under open conditions.
abstract: Fourteen cases of depression resistant to multiple treatments were treated by lithium augmentation of fluoxetine. Tolerability of the treatment was poor. Lithium and fluoxetine may be a possible treatment for resistant depression but there is caution regarding tolerability and toxicity with the relatively high doses of lithium used in this series.
authors.affiliation: Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK.
authors.forename: C J
authors.initials: CJ
authors.lastname: Hawley
authors.forename: A G
authors.initials: AG
authors.lastname: Roberts
authors.forename: D S
authors.initials: DS
authors.lastname: Baldwin
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D016651:Lithium Carbonate / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D005473:Fluoxetine; D016651:Lithium Carbonate