Fate of renal allografts transplanted in patients with urinary diversion.
Fifty-five kidneys were transplanted into 50 patients with supravesical urinary diversion at 16 transplant centers between 1970 and 1991. Of the 32 males and 18 females, 40 were adults (> or = 18 years) and 10 were less than 18 years old at the time of first transplant. Mean follow-up was 7.8 years. At last follow-up, 94% of recipients were alive and 73% of the kidneys were functioning. Fifteen kidneys were lost: 9 to rejection, 3 to noncompliance, and 3 patients died with a functioning kidney. Ten (18%) transplants were followed by surgical complications. Twenty-four (44%) were followed by medical complications of which urinary tract infection was most common. Recipients age 18 or younger had more urinary tract infections than older patients. No patient had urinary stones and no patient required medical treatment for metabolic abnormalities. We conclude that drainage of kidney transplants into a supravesical urinary diversion is an effective treatment for end-stage renal disease patients without adequate urinary bladders.
Hatch
D A
DA
Urologic Society for Transplantation and Vascular Surgery, Los Angeles, California 90024-1738.
Belitsky
P
P
Barry
J M
JM
Novick
A C
AC
Taylor
R J
RJ
Jordan
M L
ML
Sagalowsky
A I
AI
Zaontz
M R
MR
D000328:Adult; D002648:Child; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation / Q000401:mortality / Q000502:physiology; D015993:Life Tables; D008297:Male; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome; D014547:Urinary Diversion
D003404:Creatinine