title: Large-scale randomized evidence: large, simple trials and overviews of trials.
authors.affiliation: ICRF/MRC/BHF Clinical Trial Service Unit, University of Oxford, United Kingdom.
authors.forename: R
authors.initials: R
authors.lastname: Peto
authors.forename: R
authors.initials: R
authors.lastname: Collins
authors.forename: R
authors.initials: R
authors.lastname: Gray
mesh_terms: D001241:Aspirin / Q000627:therapeutic use; D015982:Bias; D001943:Breast Neoplasms / Q000628:therapy; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000401:mortality; D015987:Effect Modifier, Epidemiologic; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006302:Health Services Research; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use; D008297:Male; D015201:Meta-Analysis as Topic; D008875:Middle Aged; D016016:Proportional Hazards Models; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D015996:Survival Rate; D013629:Tamoxifen / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D013629:Tamoxifen; D008274:Magnesium; D001241:Aspirin