Synthesis and anticholinergic activity of some new N,N-disubstituted carbamodithioic acid 2-oxo-2-(diphenylamino) ethyl esters.
The synthesis of new N,N-disubstituted carbamodithioic acid 2-oxo-2-(diphenylamino) ethyl esters is reported. The structures of these compounds are supported by their UV, IR and 1H-NMR spectra, as well as by elemental analysis. The new compounds were tested for their anticholinergic activities.
Ozkanli
F
F
Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara-Turkey.
Dalkara
S
S
Calis
U
U
Erol
K
K
Ozdemir
M
M
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005260:Female; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010276:Parasympatholytics / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013859:Thiocarbamates / Q000138:chemical synthesis* / Q000494:pharmacology
D010276:Parasympatholytics; D013859:Thiocarbamates; D001285:Atropine; D000109:Acetylcholine