Immunization of chickens with live Newcastle disease vaccine adjuvanted with oil.
Chickens of various ages and breeds were vaccinated subcutaneously with Newcastle disease live-in-oil vaccines. These vaccines were prepared immediately prior to the vaccination by mixing the lyophilized live vaccine with the oil adjuvant, which was kept at room temperature. The live-in-oil vaccines were shown to be 30-50 times more effective in efficacy tests than either the same vaccines reconstituted in water or killed-in-oil vaccines. In addition to its biological advantage, the method of preparation of live-in-oil vaccine saves the expensive space of cold storage and shipment necessary for conventional killed-in-oil vaccines.
Peleg
B A
BA
State Laboratory for Vaccine Control, Kimron Veterinary Institute, Bet Dagan, Israel.
Samina
I
I
Brenner
J
J
D000276:Adjuvants, Immunologic; D000818:Animals; D002645:Chickens / Q000276:immunology*; D008297:Male; D009521:Newcastle Disease / Q000517:prevention & control*; D009522:Newcastle disease virus / Q000276:immunology*; D009821:Oils; D014611:Vaccination / Q000662:veterinary; D014765:Viral Vaccines / Q000008:administration & dosage
D000276:Adjuvants, Immunologic; D009821:Oils; D014765:Viral Vaccines