title: Role of the vitreous in the prognosis of peripheral uveitis.
abstract: We studied 116 eyes with peripheral uveitis (mean follow-up, 5.0 years) to ascertain the effect of the vitreous on prognosis. At the initial examination, the prevalence of partial posterior vitreous detachment was significantly higher in eyes with macular edema (27%) than in those without (7%, P = .01). During follow-up, the prevalence of no posterior vitreous detachment initially was significantly higher in eyes that developed macular edema (78%) than in those that did not (22%, P = .01). The prevalence of no or partial posterior vitreous detachment was also significantly higher in eyes with decreased visual acuity of three or more Snellen lines (57% and 38%, respectively) compared with those with visual acuity decreases of two Snellen lines or less (21% and 11%; P = .02 and P = .01, respectively). Eyes with peripheral uveitis with vitreous adhesion may have a less favorable prognosis compared with those with complete posterior vitreous detachment.
authors.affiliation: Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114.
authors.forename: T
authors.initials: T
authors.lastname: Hikichi
authors.forename: C L
authors.initials: CL
authors.lastname: Trempe
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008269:Macular Edema / Q000175:diagnosis / Q000209:etiology; D008297:Male; D015995:Prevalence; D011379:Prognosis; D012163:Retinal Detachment / Q000209:etiology; D012189:Retrospective Studies; D014605:Uveitis / Q000150:complications* / Q000503:physiopathology; D014792:Visual Acuity; D014822:Vitreous Body / Q000473:pathology / Q000502:physiology*