[Morphologic classification of glomerulonephritis revisited].
The use of a wide spectrum of monoclonal antibodies allowed us to distinguish two groups of glomerulopathies: inflammatory (glomerulonephritis) and non-inflammatory. Glomerulus infiltration with inflammatory cells, glomerulus cell proliferation, heterogeneous composition and localization of the immune complex depositions even within one morphological form are characteristic of inflammatory glomerulopathies. A proliferative reaction is practically absent in non-inflammatory glomerulopathies, localization and deposits composition within one morphological form is homogeneous, the appearance of non-immune deposits containing only fibrin or low-density lipoproteins is typical. Specific podocyte marker, antigen of acute lymphoblastic leukemia, is practically absent at early stages of non-inflammatory glomerulopathies.
Ivanov
A A
AA
Pal'tsev
M A
MA
Serov
V V
VV
Varshavskiĭ
V A
VA
D015415:Biomarkers / Q000032:analysis; D002455:Cell Division / Q000502:physiology; D005921:Glomerulonephritis / Q000145:classification / Q000473:pathology*; D006801:Humans; D007249:Inflammation / Q000473:pathology
D015415:Biomarkers
Eshche raz o morfologicheskoĭ klassifikatsii glomerulonefrita.