title: Syphilitic placentitis: an immunopathy.
abstract: The placentas of eight infants with congenital syphilis were examined by both immunohistochemical and immunofluorescent techniques. Significant IgM, C3 and rheumatoid factor reactivity were observed in all the syphilitic placentas. We postulate that their presence plays an important role in the evolution of the pathological changes.
authors.affiliation: Department of Paediatrics, Groote Schuur Hospital, University of Cape Town, RSA.
authors.forename: G R
authors.initials: GR
authors.lastname: Samson
authors.forename: M P
authors.initials: MP
authors.lastname: Meyer
authors.forename: D R
authors.initials: DR
authors.lastname: Blake
authors.forename: M C
authors.initials: MC
authors.lastname: Cohen
authors.forename: S C
authors.initials: SC
authors.lastname: Mouton
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007150:Immunohistochemistry; D010920:Placenta / Q000737:chemistry / Q000473:pathology; D010922:Placenta Diseases / Q000150:complications* / Q000276:immunology / Q000473:pathology; D011247:Pregnancy; D012217:Rheumatoid Factor / Q000032:analysis; D013590:Syphilis, Congenital / Q000150:complications* / Q000276:immunology / Q000473:pathology
chemical_list: D000936:Antigen-Antibody Complex; D003176:Complement C3; D007075:Immunoglobulin M; D012217:Rheumatoid Factor