Lithium-induced parathyroid dysfunction: a case report and review of the literature.
OBJECTIVE
Twenty-six cases of lithium-induced hyperparathyroidism have been reported in the literature. This article describes an additional case that illustrates current management recommendations.


METHODS
Case report. Clinical presentation and proposed mechanisms of the suspected drug-induced effect are discussed.


CONCLUSIONS
Serum calcium concentrations should be determined before and periodically during long-term lithium carbonate therapy. Discontinuation of therapy in patients who develop lithium-induced parathyroid dysfunction generally corrects calcium and parathyroid hormone concentrations. Surgery is indicated in patients with complications of hyperparathyroidism.
Taylor
J W
JW
University of Mississippi, Jackson 39216.
Bell
A J
AJ
D000328:Adult; D000368:Aged; D006801:Humans; D006961:Hyperparathyroidism / Q000139:chemically induced* / Q000628:therapy; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged
D008094:Lithium