title: [7-fluoro-4-chromone-3-sulfur compounds].
abstract: The novel 7-fluoro-4-chromone-3-sulfur compounds 5-12 were synthesized from the sulfinic acid 4, which can be obtained from the enaminone 3 and thionyl chloride. Especially the Flosequinane-like sulfoxide 12 was prepared and the vasodilating activity was evaluated in isolated ring segments of rat aorta.
authors.affiliation: Institut für Pharmazie, Freien Universität Berlin.
authors.forename: W
authors.initials: W
authors.lastname: Löwe
authors.forename: S
authors.initials: S
authors.lastname: Elz
authors.forename: H
authors.initials: H
authors.lastname: Reiser
authors.forename: S
authors.initials: S
authors.lastname: Schott
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects; D002867:Chromones / Q000138:chemical synthesis* / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D014665:Vasodilator Agents / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D002867:Chromones; D014665:Vasodilator Agents
vernacular_title: 7-Fluor-4-chromon-3-Schwefel-Verbindungen.