title: [Outcome of conservative treatment of high-degree vesicoureteral reflux].
abstract: We performed a retrospective study to evaluate the results of a nonsurgical approach of primary high grade vesicoureteral reflux (VUR). 241 patients (209 III and 32 IV) were reviewed during and average time of 9.4 years. 55% of them were under 6 months and 52% had bilateral reflux (50% III and 63% IV). During the observation period spontaneous resolution of reflux was observed in 126 (60%) with grade III at 5 years and 26% in patient with grade IV at 4 years. In both grades the duration of persistent reflux was analyzed using life-table method. When age at presentation was compared with duration of reflux there was a shorter time of reflux in those patients presenting from age 0 to 6 months. New renal scars developed in 5 patients during the period of observational therapy. We conclude that high grade VUR can resolve over a protracted interval. On basis of this analysis, we advocate the surgical correction in these patients after 5-year period to grade III and 2-year to grade IV.
authors.affiliation: Unidad de Urología Infantil, Hospital Infantil La Paz, Madrid.
authors.forename: M J
authors.initials: MJ
authors.lastname: Martínez Urrutia
authors.forename: R
authors.initials: R
authors.lastname: Muguerza
authors.forename: F
authors.initials: F
authors.lastname: Eire
authors.forename: P
authors.initials: P
authors.lastname: López Pereira
authors.forename: A
authors.initials: A
authors.lastname: Hasan
authors.forename: L
authors.initials: L
authors.lastname: Espinosa
authors.forename: E
authors.initials: E
authors.lastname: Jaureguizar
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D014718:Vesico-Ureteral Reflux / Q000145:classification / Q000628:therapy*
vernacular_title: Resultados del tratamiento conservador en el reflujo vesicoureteral de alto grado.