title: [Role of heart transplantation in the treatment of complex congenital malformations in adolescents and adults].
abstract: The number of pediatric heart transplants for complex congenital heart disease has increased in recent years, but little experience has been reported in the adolescent and adult population. Between 1987 and 1992, 6 patients (mean age 24 years, range 14 to 42) underwent transplant in our institution because of structural congenital heart disease with or without prior palliative operation or definitive repair. The diagnose covered: congenitally corrected transposition of the great vessels, late systemic ventricular failure after surgically corrected transposition of the great arteries, left superior vena cava, and tricuspid atresia with right ventricular hypoplasia. The palliative repairs included modified Blalock-Taussig shunt, cavo-pulmonary Glenn shunt, two aorto-pulmonary Waterstone shunts, two Blalock-Hanlon atrioseptectomies and one pulmonary valvotomy by the method of Brock. One patient had undergone pulmonary artery banding, in two patients atrial repair by Senning's technique had been performed for definitive repair of transposition of the great arteries. Donor cardiectomy was modified to remove complete inflow and outflow tissue and transplantation was performed without prosthetic material in all patients, in no case was deep hypothermic arrest necessary. There was no early or late mortality after a mean follow-up of 28 months. Postoperative echocardiography and cardiac catheterization demonstrated perfect anatomical and functional results. There was no early or late mortality after a mean follow-up of 28 months. Postoperative echocardiography and cardiac catheterization demonstrated perfect anatomical and functional results. Adult patients with complex congenital cardiac diseases can be transplanted with a very low perioperative risk, even after several prior operative procedures.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Clinique de chirurgie cardiovasculaire, Hôpital universitaire, Zurich.
authors.forename: T
authors.initials: T
authors.lastname: Carrel
authors.forename: M
authors.initials: M
authors.lastname: Ritter
authors.forename: M
authors.initials: M
authors.lastname: Maggiorini
authors.forename: R
authors.initials: R
authors.lastname: Jenni
authors.forename: F
authors.initials: F
authors.lastname: Real
authors.forename: M
authors.initials: M
authors.lastname: Turina
mesh_terms: D000293:Adolescent; D000328:Adult; D000714:Anastomosis, Surgical / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000601:surgery*; D006334:Heart Function Tests; D016027:Heart Transplantation / Q000379:methods; D006801:Humans; D008297:Male; D014188:Transposition of Great Vessels / Q000601:surgery
vernacular_title: Rôle de la transplantation cardiaque dans le traitement des malformations congénitales complexes chez l'adolescent et l'adulte.