title: Transferrin-binding capacity by rat bone marrow populations containing different proportions of erythroid cells.
abstract: The transferrin-binding capacity of rat bone marrow cells and different erythroid-enriched populations from rat bone marrow has been studied and compared with that previously reported for pure reticulocyte populations. Two components with different transferrin-binding capacities were found. The one with higher affinity was present mainly in erythroid cells and showed an association constant similar to that observed in reticulocyte populations. The component with a lower transferrin affinity was observed mainly in bone marrow fractions containing low proportions of erythroid cells.
authors.affiliation: Departamento de Bioquímica y Biología Molecular, Universidad de Alcalá de Henares, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Mendieta
authors.forename: P
authors.initials: P
authors.lastname: Sancho
authors.forename: J
authors.initials: J
authors.lastname: Luque
mesh_terms: D000740:Anemia / Q000378:metabolism; D000818:Animals; D001853:Bone Marrow / Q000378:metabolism*; D001854:Bone Marrow Cells; D004900:Erythroblasts / Q000378:metabolism; D015672:Erythroid Precursor Cells / Q000378:metabolism*; D006801:Humans; D008297:Male; D011485:Protein Binding; D051381:Rats; D017208:Rats, Wistar; D012156:Reticulocytes / Q000378:metabolism; D014168:Transferrin / Q000378:metabolism*
chemical_list: D014168:Transferrin