title: Intraperitoneal cisplatin and carboplatin in the management of ovarian cancer.
abstract: The intraperitoneal delivery of cisplatin or carboplatin in the management of ovarian cancer is based on a sound pharmacokinetic rationale. Objective responses, including surgically documented complete responses, have been observed in patients with ovarian cancer who have previously responded to systemic platinum-based therapy. A precise role for intraperitoneal cisplatin or carboplatin in the management of ovarian cancer remains to be defined.
authors.affiliation: Cleveland Clinic Cancer Center, OH.
authors.forename: M
authors.initials: M
authors.lastname: Markman
mesh_terms: D016190:Carboplatin / Q000008:administration & dosage* / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D016879:Salvage Therapy
chemical_list: D016190:Carboplatin; D002945:Cisplatin