Amphetamine-induced modification of quinine palatability: analysis by the taste reactivity test.
The effects of low doses of d-amphetamine (0.25-0.5 mg/kg, IP) on taste reactions elicited by quinine solutions in a 5-10-min taste reactivity test were assessed in a series of three experiments. Amphetamine consistently suppressed aversive reactions elicited by quinine solutions. The results suggest that amphetamine, like morphine, attenuates the aversiveness of the taste of quinine solution.
Parker
L
L
Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada.
Leeb
K
K
D000818:Animals; D003913:Dextroamphetamine / Q000494:pharmacology*; D004327:Drinking Behavior / Q000187:drug effects; D008297:Male; D009020:Morphine / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects; D009271:Naltrexone / Q000494:pharmacology; D010868:Pimozide / Q000494:pharmacology; D011803:Quinine / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013395:Sucrose / Q000494:pharmacology; D013649:Taste / Q000187:drug effects*
D010868:Pimozide; D013395:Sucrose; D009271:Naltrexone; D009020:Morphine; D011803:Quinine; D003913:Dextroamphetamine