title: Color Doppler study of mitral regurgitation during percutaneous transluminal coronary angioplasty.
abstract: Mitral regurgitation (MR) was evaluated by color Doppler echocardiography during percutaneous transluminal coronary angioplasty (PTCA) in 28 patients with one-vessel artery disease (left anterior descending artery in 11, right coronary artery in 8, and circumflex artery in 9) and normal left ventricular function. In all three groups, left ventricular ejection fraction (LVEF) and wall motion score index (WMSI) decreased significantly during artery occlusion in comparison with baseline values (no differences among various groups). Anterior and inferior akinesia/dyskinesia was observed in all patients during left anterior descending and right coronary artery occlusion, respectively. Lateral akinesia/dyskinesia was induced by occlusion of the circumflex artery in six patients (all with proximal lesions [p < 0.05 vs the other two groups]) and the right coronary artery in one. Only the six patients with circumflex artery occlusion showed PTCA-related MR (> 2+ in two). LVEF and WMSI were similar during artery occlusion in patients with and without MR. Neither mitral leaflet prolapse nor anulus dilation occurred during PTCA in any of the patients. Our data show that during brief occlusion of the proximal circumflex artery, functional MR (usually mild) frequently occurs in relation to specific lateral akinesia/dyskinesia.
authors.affiliation: Institute of Cardiology, Catholic University Sacro Cuore, Rome, Italy.
authors.forename: L M
authors.initials: LM
authors.lastname: Biasucci
authors.forename: A
authors.initials: A
authors.lastname: Lombardo
authors.forename: E
authors.initials: E
authors.lastname: Rossi
authors.forename: F
authors.initials: F
authors.lastname: Pennestri
authors.forename: R
authors.initials: R
authors.lastname: Mongiardo
authors.forename: M
authors.initials: M
authors.lastname: Mazzari
authors.forename: G
authors.initials: G
authors.lastname: Alecce
authors.forename: M
authors.initials: M
authors.lastname: Testa
authors.forename: A
authors.initials: A
authors.lastname: Costalunga
authors.forename: F
authors.initials: F
authors.lastname: Loperfido
mesh_terms: D000208:Acute Disease; D000368:Aged; D000704:Analysis of Variance; D015906:Angioplasty, Balloon, Coronary; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D003327:Coronary Disease / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy; D015150:Echocardiography, Doppler / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D004562:Electrocardiography; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology