title: Septa in the liver of patients with chronic hepatic schistosomiasis japonica: MR appearance.
abstract: OBJECTIVE
  Chronic hepatic schistosomiasis japonica is a disorder characterized by broad fibrous septa in the liver. The ability to recognize these septa on MR images might enable distinction of this lesion from other cirrhotic disorders. The purpose of this study was to analyze the MR appearance of these septa.
  
  
  METHODS
  MR images of 18 patients who had typical calcifications of hepatic septa on CT scans were reviewed. The diagnosis was proved by biopsy in six patients. In the remaining 12, stool examinations were positive for schistosomiasis. T1-weighted MR images and T2-weighted and intermediate (long repetition time and short echo time) MR images acquired with the use of gradient-moment nulling were obtained in all 18 patients. In eight of 18 patients, additional T2-weighted and intermediate images were obtained without gradient-moment nulling. Fifteen patients had contrast-enhanced T1-weighted images. The presence of abnormal MR signal and its intensity at sites corresponding to the septa seen on CT scans were studied.
  
  
  RESULTS
  MR images showed the septa as linear abnormalities frequently seen in the subdiaphragmatic portion of the right lobe of the liver. On T1-weighted images, septa had low signal intensity and were identified in nine of 18 patients. On T2-weighted images obtained with gradient-moment nulling, septa had high signal intensity and were seen in 13 of 18 patients. On T2-weighted images obtained without gradient-moment nulling, the septa had primarily low signal intensity and were seen in five of eight patients. On intermediate MR images obtained with gradient-moment nulling, the septa had primarily high signal intensity and were seen in nine of 18 patients. On intermediate images obtained without gradient-moment nulling, the septa had primarily low signal intensity and were seen in four of eight patients. In nine of 15 patients, septa were visualized as high-signal-intensity lesions on contrast-enhanced T1-weighted images. In 14 of 18 patients, the septa were detected in one or more sequences.
  
  
  CONCLUSIONS
  Our experience suggests that MR imaging in patients with chronic schistosomiasis of the liver depicts the morphologic features of hepatic septa. MR signal characteristics of septa are not unique, but use of gradient-moment nulling alters the signal intensity of septa, similar to that of blood vessels, on intermediate and T2-weighted images.
authors.affiliation: Department of Radiology, Yamanashi Medical College, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Monzawa
authors.forename: K
authors.initials: K
authors.lastname: Ohtomo
authors.forename: H
authors.initials: H
authors.lastname: Oba
authors.forename: Y
authors.initials: Y
authors.lastname: Nogata
authors.forename: K
authors.initials: K
authors.lastname: Kachi
authors.forename: G
authors.initials: G
authors.lastname: Uchiyama
mesh_terms: D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008099:Liver / Q000469:parasitology / Q000473:pathology*; D008109:Liver Diseases, Parasitic / Q000453:epidemiology / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D012554:Schistosomiasis japonica / Q000453:epidemiology / Q000473:pathology*; D014057:Tomography, X-Ray Computed