The use of microsatellites in zygosity diagnosis of twins.
Although numerous genetic and anthropological markers are available for determining zygosity of twins, there is still a need for a more practical and informative method in zygosity diagnosis. Dinucleotide repeats or other short repeats (microsatellites) are highly variable between individuals and offer a simple, fast, cheap, and exact approach for zygosity determination. The feasibility of a set of microsatellites to be used for this purpose is demonstrated.
Erdmann
J
J
Institutes of Human Genetics, University of Bonn, Germany.
Nöthen
M M
MM
Stratmann
M
M
Fimmers
R
R
Franzek
E
E
Propping
P
P
D000483:Alleles; D001483:Base Sequence; D015342:DNA Probes; D004276:DNA, Satellite / Q000235:genetics*; D005858:Germany; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic; D044465:White People / Q000235:genetics
D015342:DNA Probes; D004276:DNA, Satellite