title: Serum level of immunosuppressive acidic protein in haemodialysis patients with or without renal cell carcinoma.
abstract: OBJECTIVE
  To assess the significance of immunosuppressive acidic protein (IAP) for detection of renal cell carcinoma in patients undergoing haemodialysis.
  
  
  METHODS
  The serum concentration of both IAP and creatinine was measured in 74 patients undergoing haemodialysis, 10 of whom had renal cell carcinoma and 64 of whom had no renal cell carcinoma. Control data was obtained from 13 healthy blood donors.
  
  
  RESULTS
  The serum IAP level of patients undergoing haemodialysis was significantly elevated compared with that of the controls. The serum level of IAP in patients with renal cell carcinoma who were undergoing haemodialysis was also considerably higher than that of patients with no renal cell carcinoma. The serum creatinine levels were not significantly different between patients with and without renal cell carcinoma but were significantly elevated when compared with the controls.
  
  
  CONCLUSIONS
  The measurement of serum IAP concentration is of value in the detection of renal cell carcinoma in patients undergoing haemodialysis.
authors.affiliation: Department of Urology, Yamagata University, School of Medicine, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Sasagawa
authors.forename: T
authors.initials: T
authors.lastname: Nakada
authors.forename: Y
authors.initials: Y
authors.lastname: Kubota
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Sawamura
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D002292:Carcinoma, Renal Cell / Q000097:blood / Q000175:diagnosis*; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000097:blood / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000097:blood*; D006435:Renal Dialysis
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; C030193:immunosuppressive acidic protein; D003404:Creatinine