title: [Special MR methods for primary bone tumors: II. Volume selective 1H-spectroscopy].
abstract: The method of localised 1H MR spectroscopy was used in 19 examinations in 9 patients with primary bone tumours in order to obtain spectral signals and to determine whether these are specific for tumour classification. The spectra were obtained by a double spin echo method and the tumour tissue showed very high water content and only minor lipid and proton signals which showed J-coupling characteristics. The latter are not found in normal bone marrow and are probably due to products of tumour metabolism. The resolution of the spectra within a 13 mm or 20 mm tissue cube depends largely on the structural homogeneity of the tumour. The signal patterns in the spectra were not specific to histological tumour types.
authors.affiliation: Abteilung für Radiologische Diagnostik, Eberhard-Karls-Universität Tübingen.
authors.forename: F
authors.initials: F
authors.lastname: Schick
authors.forename: S
authors.initials: S
authors.lastname: Duda
authors.forename: M
authors.initials: M
authors.lastname: Laniado
authors.forename: W I
authors.initials: WI
authors.lastname: Jung
authors.forename: C D
authors.initials: CD
authors.lastname: Claussen
authors.forename: O
authors.initials: O
authors.lastname: Lutz
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis*; D002648:Child; D002813:Chondrosarcoma / Q000175:diagnosis*; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis*; D012512:Sarcoma, Ewing / Q000175:diagnosis*
vernacular_title: Spezielle MR-Methoden bei primären Knochentumoren: II. Volumenselektive 1H-Spektroskopie.