title: [Studies on percutaneous absorption of ruyi jinhuang san patcher with radioisotope tracer].
abstract: Berberine is one of the active ingredients in Ruyi Jinhuang San Patcher. With 3H-berberine as the tracer, a radio-labelled method was used for determining percutaneous rate and drug concentration of berberine in plasma in vivo and in vitro. A study on the percutaneous rate of different technological plasters and various animal skins was also carried out.
authors.affiliation: Hospital of Hubei, Traditional Chinese Medical College, Wuhan.
authors.forename: H W
authors.initials: HW
authors.lastname: Zhao
authors.forename: Z
authors.initials: Z
authors.lastname: Shen
authors.forename: B
authors.initials: B
authors.lastname: Zhou
authors.forename: X
authors.initials: X
authors.lastname: Lin
authors.forename: M
authors.initials: M
authors.lastname: Ye
mesh_terms: D000818:Animals; D001599:Berberine / Q000493:pharmacokinetics*; D004365:Drugs, Chinese Herbal / Q000493:pharmacokinetics*; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009132:Muscles / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D012867:Skin / Q000378:metabolism; D012869:Skin Absorption; D013045:Species Specificity; D013678:Technology, Pharmaceutical
chemical_list: D004365:Drugs, Chinese Herbal; D001599:Berberine