Schistosoma haematobium cercarial host-finding and host-recognition differs from that of S. mansoni.
Schistosoma haematobium cercarial host-finding responses differ from those of Schistosoma mansoni. The attachment response to warm substrata is more sensitive and intense and is inhibited by unphysiologically warm substrata. Attachment is also stimulated by L-arginine as the exclusive chemical cue of the human skin surface (threshold 3 microM); however, the response is drastically lower than that of S. mansoni cercariae. No chemical host stimulus could be identified for an enduring contact with the host after attachment. After attachment, the cercariae creep in a temperature gradient toward heat source; their response is, however, more sensitive than that of S. mansoni (threshold 0.03 vs. 0.15 C/mm). Creeping S. haematobium cercariae orientate in chemical gradients in the same way as S. mansoni cercariae toward L-arginine as the exclusive chemical signal of the human skin surface. The selective benefit of this behavior is not yet understood. The penetration of both species is stimulated by free fatty acids from the human skin surface, not by heat. Thus, S. haematobium responds more to thermal host signals, whereas S. mansoni prefers chemical host signals.
Haas
W
W
Institut für Zoologie I, Universität Erlangen-Nürnberg, Germany.
Haberl
B
B
Schmalfuss
G
G
Khayyal
M T
MT
D000818:Animals; D001120:Arginine / Q000378:metabolism; D003470:Culture Media; D005227:Fatty Acids / Q000378:metabolism; D006790:Host-Parasite Interactions; D006358:Hot Temperature; D006801:Humans; D009068:Movement; D012548:Schistosoma haematobium / Q000502:physiology*; D012550:Schistosoma mansoni / Q000502:physiology*; D012867:Skin / Q000737:chemistry / Q000469:parasitology*; D013550:Swimming
D003470:Culture Media; D005227:Fatty Acids; D001120:Arginine