title: Automated DNA sequencing: an image processing approach.
abstract: An automatic DNA sequencing analysis system has been developed by Scanalytics/CSPI. The strategies used to solve some of the common problems in the automation of DNA sequencing systems will be discussed. Algorithms developed include fast image background correction, automatic base detection, resolution enhancement by deconvolution, desmiling and artificial intelligence algorithms for sequence interpretation.
authors.affiliation: Scanalytics/CSPI, Billerica, MA 01821.
authors.forename: Y
authors.initials: Y
authors.lastname: Wu
authors.forename: D
authors.initials: D
authors.lastname: Mislan
mesh_terms: D000465:Algorithms; D016477:Artifacts; D001331:Automation; D001483:Base Sequence; D004247:DNA / Q000032:analysis*; D007091:Image Processing, Computer-Assisted; D008969:Molecular Sequence Data; D015203:Reproducibility of Results
chemical_list: D004247:DNA