Gastrointestinal effects and energy value of polydextrose in healthy nonobese men.
We studied seven healthy volunteers before and during acute (PD1) and chronic (PD2) ingestion of 30 g polydextrose (PD)/d. The energy value of PD was assessed after [U-14C]PD was added to the 10-g morning dose of PD during PD1 and at the end of PD2. Thirty-one +/- five percent (mean +/- SD) (PD1) and 29 +/- 4% (PD2) of the dose appeared in breath within 48 h. A small fraction of the ingested radioactivity was recovered in urine (4 +/- 1%) and excreted in flatus (< or = 1%) and in feces as volatile fatty acids (VFAs) (< 1%) and bacteria (3-4%); the remaining radioactivity in stools, 33 +/- 3% (PD1) and 32 +/- 4% (PD2), was assumed to be intact PD. Breath excretion of the label was 49 +/- 5% after intracolonic infusion of [U-14C] acetate. The energy value of PD, calculated by means of Miller and Wolin's stoichiometric equation of colonic fermentation, was similar during PD1 and PD2: 4.0 and 6.1 kJ/g, respectively, when breath 14CO2 and VFA production from PD were used for calculation.
Achour
L
L
Unité de Recherche sur les Fonctions Intestinales, le Métabolisme et la Nutrition, INSERM Unité 290, Hôpital Saint-Lazare, Paris.
Flourié
B
B
Briet
F
F
Pellier
P
P
Marteau
P
P
Rambaud
J C
JC
D000328:Adult; D001944:Breath Tests; D002245:Carbon Dioxide / Q000032:analysis; D004064:Digestive System / Q000187:drug effects* / Q000382:microbiology; D004734:Energy Metabolism / Q000502:physiology*; D005243:Feces / Q000737:chemistry; D005285:Fermentation; D005503:Food Additives / Q000378:metabolism* / Q000494:pharmacology; D005936:Glucans / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D008297:Male; D008962:Models, Theoretical; D009765:Obesity / Q000378:metabolism; D012016:Reference Values
D005503:Food Additives; D005936:Glucans; D002245:Carbon Dioxide; C033375:polydextrose