title: [MR tomographic measurement of the diastolic relaxation of the hypertrophied left ventricle with the single-slice-multiphase technic].
abstract: In order to assess diastolic ventricular function in hypertensive patients, a single-slice multiphase sequence was used in order to measure contraction and early diastolic relaxation. There was no difference in the contraction velocity between hypertensives and normals (Vsys. n.r. = 56.1 +/- 13.8% LVDV/s vs. 51.7 +/- 8.6% LVEDV/s, stat, n. sign.). Early diastolic relaxation velocity in hypertensives was reduced as compared with the control group (Vdiast. 1n.r. = 37.9 +/- 13.1% LVEDV/s vs. 47.1 +/- 9.6% LVEDV/s, p < 0.05). There was no linear relation between abnormal relaxation and the extent of myocardial hypertrophy. Hypertensives with myocardial hypertrophy frequently had reduced early diastolic relaxation velocity. Regression analysis for estimating left ventricular volumes derived from single-slice measurements were confirmed by additional multislice measurements. The calculated LVEDV correlated at r = 0.956 with multi-slice measurements and tended to show lower values (LVEDV n.r. = 104.6 +/- 30.8 ml vs. LVEDV = 102.1 +/- 28.8 ml, r = 0.956, p < 0.05). The LVESV was overestimated by the multi-slice technique, the calculated regression volume averaged 23% lower, realistic values (LVESV n.r. = 28.5 +/- 15.3 ml vs. LVESV = 37.1 +/- 15.6 ml, r = 0.887, p < 0.001).
authors.affiliation: Klinik und Poliklinik für Radiologie, Universität Mainz.
authors.forename: M B
authors.initials: MB
authors.lastname: Pitton
authors.forename: M
authors.initials: M
authors.lastname: Just
authors.forename: F
authors.initials: F
authors.lastname: Himmelsbach
authors.forename: M
authors.initials: M
authors.lastname: Thelen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003971:Diastole; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D011446:Prospective Studies; D012016:Reference Values; D012044:Regression Analysis; D013599:Systole
vernacular_title: MR-tomographische Messung der diastolischen Relaxation hypertrophierter linker Ventrikel mit Single-slice-multi-phase-Technik.