title: Effects of balloon dilatation on canine ureteric physiology.
abstract: The concept of adynamic ureteric obstruction following balloon dilatation was explored in 12 female mongrel dogs. Upper ureteric segments were dilated to 15 french at 10 atm for 3 min. Pressure and motility in the dilated segments were compared to that proximal and distal to the dilated segment prior to, immediately after, and at 2 and 6 weeks after dilatation. Immediately after dilatation the dilated segment and proximal pelvi-ureter showed a rise in baseline pressure from 2.5 +/- 0.3 and 1.9 +/- 0.3 to 32 +/- 4.6 and 37.2 +/- 5.7 mm Hg, with an associated decrease in the amplitude of contractions. Distal ureteric pressure/motility was unaffected at this point. At 2 weeks, the motility of the pelvis, dilated segment and distal ureter was diminished. Nephrostograms showed hydronephrosis and dilated upper ureteric segments with extravasation in 2 animals. At 6 weeks there was residual dilatation but motility of the dilated segment, and that of the proximal pelvi-ureter and distal ureter had returned to normal.
authors.affiliation: Department of Surgery/Urology, Mater Misericordiae Hospital and University College, Dublin, Ireland.
authors.forename: G M
authors.initials: GM
authors.lastname: Lennon
authors.forename: J M
authors.initials: JM
authors.lastname: Fitzpatrick
mesh_terms: D000818:Animals; D002404:Catheterization / Q000009:adverse effects; D004285:Dogs; D005260:Female; D009119:Muscle Contraction / Q000502:physiology; D009130:Muscle, Smooth / Q000502:physiology; D011312:Pressure; D013997:Time Factors; D014513:Ureter / Q000502:physiology*; D014517:Ureteral Obstruction / Q000209:etiology*