[The effect of dimephosphon, sermion and piracetam on the reactivity of the cerebral vessels, on local cerebral blood flow and on oxygen tension in brain tissue].
The paper gives the results of experimental and clinical studies of the nootropic agents dimephosphone, sermion, and piracetam on local cerebral circulation, cerebrovascular responsiveness and O2 tension. The vasoactivity of the parameters studied has been shown to be displayed by their ability to normalize cerebrovascular responsiveness and it is associated with decreased brain tissue oxygen consumption when dimephosphone is applied and with its increased one when sermion and piracetam are used.
Danilov
V I
VI
Gorozhanin
A V
AV
Studentsova
I A
IA
D000293:Adolescent; D000328:Adult; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D001932:Brain Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology; D002536:Cerebral Arteries / Q000187:drug effects*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D002648:Child; D004341:Drug Evaluation; D004567:Electrodes, Implanted; D005910:Glioma / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D008579:Meningioma / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology; D008875:Middle Aged; D009530:Nicergoline / Q000494:pharmacology* / Q000627:therapeutic use; D009943:Organophosphorus Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D010101:Oxygen Consumption / Q000187:drug effects*; D010889:Piracetam / Q000494:pharmacology* / Q000627:therapeutic use; D011817:Rabbits; D013997:Time Factors; D014665:Vasodilator Agents / Q000494:pharmacology* / Q000627:therapeutic use
D009943:Organophosphorus Compounds; D014665:Vasodilator Agents; C049638:dimephosphon; D009530:Nicergoline; D010889:Piracetam
Vliianie dimefosfona, sermiona i piratsetama na reaktivnost' mozgovykh sosudov, lokal'nyĭ mozgovoĭ krovotok i napriazhenie kisloroda v tkani golovnogo mozga.