title: The value of the delay phenomenon in flap prefabrication: an experimental study in rabbits.
abstract: Neovascularisation of thin skin flaps after arteriovenous pedicle implantation (flap prefabrication) and the impact of the delay mechanism on the viability of these flaps were investigated. Twenty-four full thickness skin flaps were raised in twelve New Zealand white rabbits. Delay incisions were made at the lateral borders of the planned flaps at the same time as pedicle implantation, 1 week before pedicle implantation, or 1 week after pedicle implantation and the flaps based on the implanted vessels raised at 2 weeks after implantation. Flap survival assessed at 1 week was found to be improved when flap delay was performed 1 week before or after pedicle implantation. Angiographic studies demonstrated an increased density and linearity of the vascular pattern in these delay group flaps. The combination of the time-tested concept of delaying a flap with the newer technique of flap prefabrication appears to improve flap viability.
authors.affiliation: Brigham and Women's Hospital, Boston.
authors.forename: P K
authors.initials: PK
authors.lastname: Maitz
authors.forename: J J
authors.initials: JJ
authors.lastname: Pribaz
authors.forename: F J
authors.initials: FJ
authors.lastname: Duffy
authors.forename: C A
authors.initials: CA
authors.lastname: Hergrueter
mesh_terms: D000792:Angiography; D000818:Animals; D005260:Female; D006085:Graft Survival / Q000502:physiology; D011817:Rabbits; D012867:Skin / Q000098:blood supply; D013524:Surgical Flaps / Q000379:methods* / Q000502:physiology; D013997:Time Factors