title: [Lung interstitial disease in systemic sclerosis: semiologic characteristics with high-resolution computerized tomography and comparison with other methods].
abstract: In 28 patients with systemic sclerosis interstitial lung involvement was investigated with high-resolution Computed Tomography (HRCT) in comparison with other diagnostic methods (respiratory function tests, lung scintigraphy and conventional radiography of the chest). The most frequent CT signs were: interlobular septal thickening, intralobular interstitial thickening, and ground-glass density. Their distribution was generally basal and posterior and high correlation was observed between the extent of lung disease and the cutaneous pattern of scleroderma. Pathological findings were present in 93% of cases: HRCT can must be considered more effective than the other methods in the evaluation of systemic sclerosis and should therefore be a fundamental diagnostic tool in the study and follow-up of interstitial diseases in the patients with systemic sclerosis.
authors.affiliation: II Cattedra di Radiologia, Facoltà di Medicina, Università Federico II, Napoli.
authors.forename: A
authors.initials: A
authors.lastname: Rotondo
authors.forename: R
authors.initials: R
authors.lastname: Grassi
authors.forename: O
authors.initials: O
authors.lastname: Catalano
authors.forename: L
authors.initials: L
authors.lastname: Del Viscovo
authors.forename: M
authors.initials: M
authors.lastname: Vatti
authors.forename: M
authors.initials: M
authors.lastname: Gallo
authors.forename: L
authors.initials: L
authors.lastname: Bianco
authors.forename: L
authors.initials: L
authors.lastname: Celentano
authors.forename: A
authors.initials: A
authors.lastname: Brunetti
authors.forename: M
authors.initials: M
authors.lastname: Rivellini
mesh_terms: D000328:Adult; D000368:Aged; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications*; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods
vernacular_title: La patologia interstiziale polmonare nella sclerosi sistemica: caratteristiche semeiologiche con la tomografia computerizzata con alta risoluzione e confronto con altre metodiche.