title: Duodenal diaphragmlike stricture induced by acetylsalicylic acid.
abstract: Many reports have mentioned the role of nonsteroidal antiinflammatory drugs in inducing diaphragm-like strictures in the small and large bowel. These lesions are mostly seen in patients with chronic use of nonsteroidal antiinflammatory drugs. We report the case of a 57-year-old man who developed a diaphragmlike stricture in the second part of the duodenum. The patient had been using a preparation containing acetylsalicylic acid during many years. Although a congenital origin of the diaphragm is not completely excluded, we postulate that this stricture probably occurred as a result of acetylsalicylic acid-induced ulcerations, followed by submucosal fibrosis.
authors.affiliation: Department of Internal Medicine, Middleheim General Hospital, Antwerpen, Belgium.
authors.forename: G H
authors.initials: GH
authors.lastname: Blinder
authors.forename: M L
authors.initials: ML
authors.lastname: Hautekeete
authors.forename: J P
authors.initials: JP
authors.lastname: Holvoet
authors.forename: M M
authors.initials: MM
authors.lastname: Kockx
authors.forename: H K
authors.initials: HK
authors.lastname: Hubens
mesh_terms: D001241:Aspirin / Q000009:adverse effects*; D003251:Constriction, Pathologic; D004380:Duodenal Obstruction / Q000139:chemically induced* / Q000473:pathology; D004381:Duodenal Ulcer / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D001241:Aspirin