title: Schwannoma of the nasal septum. Apropos of 2 cases.
abstract: We present two cases of schwannoma of the nasal septum. One of the patients has neurofibromatosis type 2; however, her main complaint was nasal obstruction. Schwannoma deriving from the septum is an extremely rare pathology, both in systemic neurofibromatosis type 2 and as a solitary lesion. There are no characteristic symptoms. Histopathologic examination may be inconclusive so that the definitive diagnosis requires immunohistochemic studies or electron microscopy. Differential diagnosis includes several neurogenic and mesenchymal tumors. CT scan and MRI studies are helpful in evaluating the origin, localization and extension of the lesion. Complete resection of the mass is usually curative, although patients with neurofibromatosis present a higher risk of local recurrence and malignant transformation.
authors.affiliation: Clinica Otorrinolaringologica do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Brésil.
authors.forename: O
authors.initials: O
authors.lastname: Butugan
authors.forename: S S
authors.initials: SS
authors.lastname: Grasel
authors.forename: E R
authors.initials: ER
authors.lastname: de Almeida
authors.forename: A
authors.initials: A
authors.lastname: Miniti
mesh_terms: D000328:Adult; D004724:Endoscopy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000209:etiology; D009300:Nasal Septum; D009442:Neurilemmoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D016518:Neurofibromatosis 2 / Q000150:complications; D009669:Nose Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed