title: Molecular cloning of two novel protein kinase genes from Arabidopsis thaliana.
abstract: We have isolated two novel protein kinase genes, MHK and NAK, from the plant Arabidopsis thaliana by using low stringency hybridization with the catalytic domain of a putative plant receptor protein kinase. Sequence analysis of the cDNAs reveals that MHK is a member of the cdc2+ family of protein kinases and is particularly similar to the mak gene of rats; mak encodes a protein kinase that may play a role in spermatogenesis. NAK encodes a candidate protein kinase that is similar to the oncogenes met and abl. The homology that these two Arabidopsis genes share with other protein kinases suggests that they may play a role in the regulation of plant growth and development.
authors.affiliation: Division of Biological Sciences, University of Missouri-Columbia 65211.
authors.forename: T V
authors.initials: TV
authors.lastname: Moran
authors.forename: J C
authors.initials: JC
authors.lastname: Walker
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000201:enzymology / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D008969:Molecular Sequence Data; D011494:Protein Kinases / Q000235:genetics*
chemical_list: D011494:Protein Kinases