[Changes in some parameters of carbohydrate and lipid metabolism in rats with adrenaline administration in the rehabilitation period after hypokinesia].
Changes in the blood levels of glucose, lactate and free fatty acids, and glycogen in the livers and skeletal muscles of rats (n = 47) on epinephrine administration (150 mcg/kg body weight) were studied on Day 7 of a recovery period following hypokinesia of 15 and 30-day durations. In the animals exposed to restrained motor activity, as compared to normal rats, epinephrine has a less effect on glycogen content in the muscle, is not accompanied by increased serum levels of free fatty acids and results in more marked elevation of blood lactic acid levels. Adrenal control of lipolytic processes in the adipose tissue and of glycogenolytic processes in the muscles in the post-hypokinetic recovery period is reduced.
Telushkin
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Potapov
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D000222:Adaptation, Physiological; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects* / Q000378:metabolism; D004837:Epinephrine / Q000494:pharmacology*; D005230:Fatty Acids, Nonesterified / Q000032:analysis*; D006003:Glycogen / Q000032:analysis*; D007103:Immobilization; D007773:Lactates / Q000032:analysis*; D019344:Lactic Acid; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007773:Lactates; D019344:Lactic Acid; D006003:Glycogen; D004837:Epinephrine
Izmeneniia nekotorykh pokazateleĭ uglevodnogo i lipidnogo obmena u krys pri vvedenii adrenalina v vosstanovitelńyĭ period posle gipokinezii.