Apolipoprotein (a) phenotypes in cardio-cerebrovascular diseases.
Apolipoprotein (a) [Lp(a)] phenotypes of 69 myocardial infarction survivor and 56 stroke patients were reported and compared to those of 190 healthy Chinese. The results revealed that the distributions of apo(a) phenotype frequency in patients with cardio-cerebrovascular disease (CCVD) were different from those of controls. The frequency of the phenotypes S1 and S2 were remarkably higher in patients than in controls within the same single-band apo(a) phenotype. Moreover, the Lp (a) serum concentrations in CCVD patients were significantly higher than in controls within the same single-band apo (a) phenotype. The apo (a) phenotype analysis of two pedigrees were shown as a typical autosomal dominant inheritance.
Zhuang
Y Y
YY
Department of Biochemistry, Nanjing Jinling Hospital, Medical Institute, Nanjing University.
Li
J J
JJ
Wang
J J
JJ
D000328:Adult; D001054:Apolipoproteins A / Q000235:genetics* / Q000378:metabolism; D002544:Cerebral Infarction / Q000097:blood / Q000235:genetics; D002561:Cerebrovascular Disorders / Q000097:blood / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype
D001054:Apolipoproteins A