title: Analysis of ventricular activation in patients with chronic non-Q wave myocardial infarction: comparison with left ventricular asynergy and myocardial perfusion defects.
abstract: In this report, we dealt with ventricular activation abnormalities in 30 patients with previous non-Q myocardial infarction (MI) by means of the CARDIAG 128.1 device, which enables analysis of ECGs, VCGs and body surface potential maps. The diagnosis was verified by left ventriculography, echocardiography and perfusion scintigraphy. Twenty-nine healthy subjects served as the control group. Morphological findings confirmed the presence of a significant subgroup with serious left ventricular asynergy. Seven electrocardiological variables, which significantly differed from control values, disclosed that non-Q MI is responsible for localized activation time prolongation, and that inferoposterior scars tend to delay the entire activation of ventricles, and to cause disturbances of the terminal depolarization phase together with a decrease in voltage production during QRS. Lesions of the anterior wall and the apicomesial part of the inferoposterior wall affect the distribution of the Q wave more often than the posterior basal ones. The probability of such abnormalities increases with the degree of asynergy. Some VCG criteria increase the sensitivity of electrocardiological analysis. These parameters will be used for evaluating the diagnostic value of electrocardiological analysis in the chronic non-Q MI. Non-Q myocardial infarctions represent a heterogeneous group of infarctions from both electrophysiological and morphological aspects.
authors.affiliation: Second Medical Department, First Faculty of Medicine, Charles University, Prague.
authors.forename: P
authors.initials: P
authors.lastname: Stovícek
authors.forename: M
authors.initials: M
authors.lastname: Stojan
authors.forename: J
authors.initials: J
authors.lastname: Kasalický
authors.forename: V
authors.initials: V
authors.lastname: Vondrácek
authors.forename: J
authors.initials: J
authors.lastname: Vojácek
authors.forename: A
authors.initials: A
authors.lastname: Linhart
authors.forename: Z
authors.initials: Z
authors.lastname: Anger
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D017202:Myocardial Ischemia / Q000503:physiopathology*; D011877:Radionuclide Imaging; D016276:Ventricular Function; D016277:Ventricular Function, Left