[DNA flow cytometry of malignant melanoma of the choroid].
Thirty-five choroidal melanomas were analyzed by flow cytometry. DNA euploidy, aneuploidy and polyploidy were found in approximately 54, approximately 46, and approximately 20% of the tumors, respectively. No correlation between histological type and ploidy was found. The synthesis phase was irregular in approximately 25 and approximately 38% of the spindle and the mixed cell melanomas, respectively. The G2M peak was broadened in approximately 50% and in approximately 23% of the spindle and the mixed cell melanomas. About 20% of the malignant melanomas were highly proliferative. In 25% of the melanomas chemotherapy seemed to be useful.
Fuchs
M
M
Augenklinik Universität Leipzig.
Wohlrab
W
W
Klapperstück
T
T
Fuchs
U
U
D001918:Brachytherapy; D002455:Cell Division / Q000502:physiology; D002829:Choroid / Q000473:pathology; D002830:Choroid Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D004273:DNA, Neoplasm / Q000032:analysis*; D015353:Eye Enucleation; D005434:Flow Cytometry; D016195:G2 Phase / Q000502:physiology; D006801:Humans; D008545:Melanoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D009367:Neoplasm Staging; D011003:Ploidies
D004273:DNA, Neoplasm
DNS-Durchflusszytometrie maligner Melanome der Chorioidea.