title: Magnetic resonance imaging in children receiving quinolones: no evidence of quinolone-induced arthropathy. A multicenter survey.
abstract: Twenty-nine children with cystic fibrosis (CF) were investigated for quinolone-induced arthropathy. Magnetic resonance imaging (MRI) was performed in 14/14 children treated with ofloxacin or ciprofloxacin and in 10/15 of those never treated with quinolones. The frequency of pathologic MRI findings, concerning cartilage thickness, careful analysis of the cartilage structure, presence of edema, cartilage-bone borderline and the presence of fluid in joints did not show any difference between both groups. Thus the presence of quinolone-induced arthrotoxicity cannot be confirmed in this study.
authors.affiliation: Department of Pediatric Nursing, Postgraduate Medical School, Bratislava, Slovak Republic.
authors.forename: A
authors.initials: A
authors.lastname: Danisovicová
authors.forename: M
authors.initials: M
authors.lastname: Brezina
authors.forename: S
authors.initials: S
authors.lastname: Belan
authors.forename: H
authors.initials: H
authors.lastname: Kayserová
authors.forename: E
authors.initials: E
authors.lastname: Kaiserová
authors.forename: I
authors.initials: I
authors.lastname: Hruskovic
authors.forename: K
authors.initials: K
authors.lastname: Orosová
authors.forename: S
authors.initials: S
authors.lastname: Dluholucký
authors.forename: K
authors.initials: K
authors.lastname: Galova
authors.forename: E
authors.initials: E
authors.lastname: Mathéova
mesh_terms: D000293:Adolescent; D002358:Cartilage, Articular / Q000473:pathology; D002648:Child; D002939:Ciprofloxacin / Q000009:adverse effects*; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000139:chemically induced*; D007719:Knee Joint / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D015242:Ofloxacin / Q000009:adverse effects*
chemical_list: D002939:Ciprofloxacin; D015242:Ofloxacin