Antineoblastic activity of antioxidant vitamins: the role of folic acid in the prevention of cervical dysplasia.
The authors made a study on 90 patients affected by various degrees of uterine cervix dysplasia searching for folic acid plasmatic concentrations. The team members affected by CIN have been compared with a test team consisting of women with normal pap-test and vaginoscopy. The study proved that the average levels of folic acids have significantly decreased in cases of dysplasia compared with the test team. These results allow stating that low folic acid plasmatic concentrations may be associated with cervix neoplasms development.
Grio
R
R
Department of Gynecology and Obstetrics, University of Turin, Italy.
Piacentino
R
R
Marchino
G L
GL
Navone
R
R
D000328:Adult; D000975:Antioxidants / Q000378:metabolism* / Q000494:pharmacology; D005260:Female; D005492:Folic Acid / Q000097:blood* / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000097:blood; D002578:Uterine Cervical Dysplasia / Q000097:blood* / Q000209:etiology / Q000517:prevention & control*
D000975:Antioxidants; D005492:Folic Acid