title: Fascioliasis: case reports and review.
abstract: Fasciola hepatica, a zoonotic liver fluke, can cause disease in humans. Fascioliasis, while common in some tropical and developing countries, is uncommon in the United States. We report two cases of fascioliasis that illustrate both the hepatic and biliary stages of the disease. Clinical features and diagnostic aspects including serologic, radiographic, and histopathologic studies are emphasized. Praziquantel was ineffective in treatment of both patients. Bithionol appears to be an effective treatment for fascioliasis.
authors.affiliation: Department of Medicine, George Washington University Medical Center, Washington, DC.
authors.forename: T A
authors.initials: TA
authors.lastname: Price
authors.forename: C U
authors.initials: CU
authors.lastname: Tuazon
authors.forename: G L
authors.initials: GL
authors.lastname: Simon
mesh_terms: D001735:Bithionol / Q000627:therapeutic use; D005211:Fascioliasis / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use
chemical_list: D011223:Praziquantel; D001735:Bithionol