[The histological study of the cochlea of the human temporal bone with the diagnosis of fetal distress].
Hypoacusia is a common audiologic sequela of hypoxia associated with fetal suffering. Nonetheless, the structural features of the cochlear lesions associated with the disorder have not been studied much. We analyzed histopathologically the cochleas of 21 newborns diagnosed as fetal suffering. Each cochlea was dissected from the temporal bone, decalcified in EDTA, included in methacrylate, sliced into serial 10 microns-thick sections, and stained with hematoxylin and eosin. The cochleas of eight newborns were eliminated because of intense autolysis. Of the 13 newborns whose cochlea were considered suitable for histopathologic study, seven had hemorrhage of the vestibular ramp and one had a ruptured Reissner's membrane. The other cochlea was were within the limits of normality. The histologic technique is discussed and the critical factor judged to be the post mortem period prior to sample fixation.
López Moya
J J
JJ
Servicio de ORL, Hospital Severo Ochoa, Leganés, Madrid.
Mico Magán
C
C
Gil-Loyzaga
P
P
D001238:Asphyxia Neonatorum / Q000150:complications*; D001344:Autopsy; D003051:Cochlea / Q000473:pathology / Q000648:ultrastructure*; D005316:Fetal Distress; D006311:Hearing Disorders / Q000151:congenital / Q000209:etiology*; D006470:Hemorrhage / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D013701:Temporal Bone / Q000601:surgery*
Estudio histológico de la cóclea de hueso temporal humano con diagnóstico de sufrimiento fetal.