title: Surgery for chronic left ventricular aneurysm. Benefits and side effects.
abstract: Seventy patients who underwent elective resection of symptomatic postinfarction apico-anterior left ventricular (LV) aneurysm with or without coronary revascularization are reviewed. The early (< or = 30 day) mortality was 5.7%. Mural thrombosis occurred in 29 cases (41.4%), unrelated to the degree of preoperative LV impairment and predictable from preoperative LV angiography in only seven cases. The response to surgery comprised significant overall improvement of global LV ejection fraction (LVEF) during rest and of all variables in stress testing. This LVEF recovery correlated significantly with that of peak ejections rate, a variable of myocardial contractility. Contrastingly, right ventricular ejection fraction (RVEF) at rest decreased slightly but significantly without correlation to preoperative RVEF or LVEF. In comparisons between patients with congestive heart failure or angina at rest as dominant symptom, the former group showed greater depression of preoperative watt and LVEF but better postoperative recovery of these variables, while right ventricular deterioration was significant only in the latter. Postoperative recovery was best in patients with poor preoperative LV function (LVEF < or = 20%), even when surgery comprised only aneurysmectomy in isolated but ungraftable LAD disease (5 cases). The observed RV deterioration may be 'nonspecific', but it must be kept in mind as a side effect of the operation, as it detracts unpredictably from postoperative ventricular recovery. Patients with well preserved preoperative LVEF, small LV aneurysm and marginal expected post-aneurysmectomy changes according to LaPlace's law are probably at risk, and surgery should then instead be directed towards preserving the remaining viable myocardium by direct revascularization.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Hospital, Uppsala, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Oxelbark
authors.forename: F
authors.initials: F
authors.lastname: Mannting
authors.forename: J
authors.initials: J
authors.lastname: Ramström
authors.forename: A
authors.initials: A
authors.lastname: Taube
authors.forename: A
authors.initials: A
authors.lastname: Henze
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005080:Exercise Test; D005260:Female; D006322:Heart Aneurysm / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D006352:Heart Ventricles / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011300:Preoperative Care; D013318:Stroke Volume; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right