title: Paratesticular leiomyosarcoma with elevated serum basic fetoprotein: a case report.
abstract: A case of paratesticular leiomyosarcoma associated with elevated serum basic fetoprotein level is reported. A 45-year-old male visited our hospital with a 6-month history of a painless left scrotal mass. High orchiectomy was performed under the diagnosis of left testicular tumor. Macroscopic and microscopic examination of the resected tumor demonstrated it to be paratesticular leiomyosarcoma. The value of serum basic fetoprotein, which is a newly identified oncofetal protein and useful as a tumor marker in some kinds of malignant neoplasm, was elevated before therapy, and its fluctuation was correlated with his clinical course. In spite of chemotherapy and resection of metastatic lesions in the lung, his condition gradually deteriorate with increasing serum basic fetoprotein level, and he died with carcinomatosis 2 years and 6 months after his admission. We suggest that basic fetoprotein is a useful tumor marker in this disease.
authors.affiliation: Department of Urology, Hyogo Medical Center for Adults, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Gohji
authors.forename: Y
authors.initials: Y
authors.lastname: Oka
authors.forename: A
authors.initials: A
authors.lastname: Higuchi
authors.forename: K
authors.initials: K
authors.lastname: Ueno
authors.forename: A
authors.initials: A
authors.lastname: Fujii
mesh_terms: D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D006801:Humans; D007890:Leiomyosarcoma / Q000097:blood* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000097:blood* / Q000175:diagnosis
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; C031192:oncofetal antigens