title: [Holmium laser versus mechanical cartilage resection. Comparative studies in the rabbit arthrosis model].
abstract: The aim of this work was to investigate and evaluate the tissue reactions after sham operation and after mechanical and holmium laser chondral debridement in a rabbit model at different postoperative intervals. In 27 rabbits an arthrosis was induced by implantation of a piece of polyethylene sheeting in one knee joint. After 5 months, distinct arthritic changes had developed. Nine animals each were randomized for sham operation, mechanical debridement, and holmium laser chondral debridement. At 1 day, 1 month, and 3 months postoperatively, three animals in each group were sacrificed and their joints examined grossly and microscopically. At 3 months after mechanical debridement the articular surface was relatively smooth, and tears and defects were filled with fibrous repair tissue. After holmium laser debridement chondral necroses were regularly found, occasionally with damage to the subchondral bone and distinct inflammation in the marrow space. The articular surface remained rough and uneven. These preliminary results suggest that use of the holmium laser is not superior to mechanical methods for remodelling and smoothing of fairly large chondral areas.
authors.affiliation: Klinik für Chirurgie, Medizinischen Universität zu Lübeck.
authors.forename: K O
authors.initials: KO
authors.lastname: Möller
authors.forename: B M
authors.initials: BM
authors.lastname: Lind
authors.forename: K
authors.initials: K
authors.lastname: Karcher
authors.forename: G
authors.initials: G
authors.lastname: Hohlbach
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000473:pathology / Q000601:surgery*; D004195:Disease Models, Animal; D005260:Female; D007719:Knee Joint / Q000473:pathology / Q000601:surgery; D053685:Laser Therapy / Q000295:instrumentation*; D010003:Osteoarthritis / Q000473:pathology / Q000601:surgery*; D011817:Rabbits
vernacular_title: Holmiumlaser versus mechanische Knorpelabtragung. Vergleichende Untersuchungen am Arthrosemodell bei Kaninchen.