title: Murine protein which binds preferentially to oligo-C-rich single-stranded nucleic acids.
abstract: Two single-stranded nucleic acid binding proteins mCBP and mCTBP were identified by means of their binding to a potential recombination hotspot in LTRs of mouse retro-transposons. Both are nuclear proteins of 35 and 55 kDa respectively. mCBP binds preferentially to oligo dC, mCTBP to oligo dCdT. mCBP was purified and its cDNA was isolated and sequenced.
authors.affiliation: Institut für Virologie und Immunbiologie, Universität Würzburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Goller
authors.forename: B
authors.initials: B
authors.lastname: Funke
authors.forename: C
authors.initials: C
authors.lastname: Gehe-Becker
authors.forename: B
authors.initials: B
authors.lastname: Kröger
authors.forename: F
authors.initials: F
authors.lastname: Lottspeich
authors.forename: I
authors.initials: I
authors.lastname: Horak
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D003001:Cloning, Molecular; D004251:DNA Transposable Elements / Q000235:genetics; D018076:DNA, Complementary / Q000096:biosynthesis; D004277:DNA, Single-Stranded / Q000235:genetics / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism*; D008099:Liver / Q000737:chemistry; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009154:Mutation / Q000235:genetics; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D011066:Poly C / Q000378:metabolism*; D011485:Protein Binding; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics; D017421:Sequence Analysis; D017386:Sequence Homology, Amino Acid; D013737:Testis / Q000737:chemistry
chemical_list: D004251:DNA Transposable Elements; D018076:DNA, Complementary; D004277:DNA, Single-Stranded; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; C087623:mCBP protein, mouse; D011066:Poly C