Fulminant hepatitis following exposure to dichlorohydrin--report of two cases.
A 34-year-old man suffered from fulminant hepatitis after cleaning a tank in which there were traces of dichlorohydrin. In spite of daily plasma exchanges, he died 10 days after exposure. A 27-year-old man with much lighter exposure showed only slight liver dysfunction. This is the first report of lethal injury following exposure to dichlorohydrin.
Shiozaki
T
T
Department of Traumatology, Osaka University Medical School, Japan.
Mizobata
Y
Y
Sugimoto
H
H
Yoshioka
T
T
Sugimoto
T
T
D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004811:Epichlorohydrin / Q000378:metabolism / Q000506:poisoning; D017809:Fatal Outcome; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects; D000517:alpha-Chlorohydrin / Q000031:analogs & derivatives* / Q000378:metabolism / Q000506:poisoning
D004811:Epichlorohydrin; C033489:1,3-dichloro-2-propanol; D000517:alpha-Chlorohydrin