title: Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment.
abstract: The authors compared Alz-50 immunoreactivity in the brain tissue of nine cognitively impaired elderly schizophrenic patients and 13 elderly comparison subjects, both without neuritic plaques or neurofibrillary tangles, and 13 patients with Alzheimer's disease. Alz-50 reactivity was absent in the schizophrenic patients, indicating that geriatric, cognitively impaired patients are unlikely to display the pathology of Alzheimer's disease.
authors.affiliation: Department of Psychiatry, Mount Sinai Medical Center, New York.
authors.forename: P
authors.initials: P
authors.lastname: Powchik
authors.forename: M
authors.initials: M
authors.lastname: Davidson
authors.forename: C B
authors.initials: CB
authors.lastname: Nemeroff
authors.forename: V
authors.initials: V
authors.lastname: Haroutunian
authors.forename: D
authors.initials: D
authors.lastname: Purohit
authors.forename: M
authors.initials: M
authors.lastname: Losonczy
authors.forename: G
authors.initials: G
authors.lastname: Bissette
authors.forename: D
authors.initials: D
authors.lastname: Perl
authors.forename: H
authors.initials: H
authors.lastname: Ghanbari
authors.forename: B
authors.initials: B
authors.lastname: Miller
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000276:immunology*; D000911:Antibodies, Monoclonal; D000941:Antigens / Q000032:analysis*; D001921:Brain / Q000276:immunology*; D003072:Cognition Disorders / Q000276:immunology*; D006801:Humans; D016874:Neurofibrillary Tangles / Q000276:immunology; D012559:Schizophrenia / Q000276:immunology*; D012565:Schizophrenic Psychology
chemical_list: C056167:Alzheimer's disease antigen; D000911:Antibodies, Monoclonal; D000941:Antigens