Seizure in a normal marrow donor: Addison's disease unmasked.
Adrenal insufficiency may be clinically occult yet cause life-threatening complications following even minor surgery. We report the case of a patient who became acutely hyponatremic after undergoing a marrow harvesting procedure using spinal anesthesia. The initial presentation mimicked the syndrome of inappropriate ADH (SIADH) secretion; however, further investigation revealed Addison's disease as the underlying cause.
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Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle 98104.
D000224:Addison Disease / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D000328:Adult; D000775:Anesthesia, Spinal / Q000009:adverse effects*; D016026:Bone Marrow Transplantation / Q000379:methods*; D005260:Female; D006801:Humans; D012640:Seizures / Q000209:etiology*; D012964:Sodium / Q000097:blood; D014019:Tissue Donors
D012964:Sodium