Phellodonic acid, a new biologically active hirsutane derivative from Phellodon melaleucus (Thelephoraceae, Basidiomycetes).
A new hirsutane derivative, phellodonic acid (1), has been isolated from fermentations of Phellodon melaleucus strain 87113. Its structure was elucidated by spectroscopic methods. The compound exhibits antibiotic activities towards bacteria and fungi. 1 is the first bioactive metabolite from cultures of a species belonging to the family Thelephoraceae.
Stadler
M
M
Lehrbereich Biotechnologie der Universität, Kaiserslautern, Bundesrepublik Deutschland.
Anke
T
T
Dasenbrock
J
J
Steglich
W
W
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000633:toxicity*; D001419:Bacteria / Q000187:drug effects*; D001487:Basidiomycota / Q000737:chemistry* / Q000254:growth & development; D002210:Caprylates / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity; D002708:Chlorella / Q000187:drug effects; D005285:Fermentation; D005658:Fungi / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity
D000900:Anti-Bacterial Agents; D002210:Caprylates; D012717:Sesquiterpenes; C083883:phellodonic acid