title: Antibacterial activity of dentinal bonding agents.
abstract: The susceptibility of five bacterial species to seven dentinal bonding agents was examined in vitro. Agar diffusion tests using filterpaper disks containing 10 microL each of conditioner, primer, or resin were performed on blood agar and mitis salivarius bacitracin agar. Chlorhexidine (0.2%) was used as a positive control. After incubation, zones of inhibited bacterial growth were measured. Of all the compounds tested, Gluma cleanser and Gluma etchant showed the strongest growth inhibition for all bacterial strains. No antibacterial effect was noted for Prisma Universal Bond 2 and Superlux Universal Bond 2 systems. The primers of Gluma, Denthesive, and Scotchbond 2 displayed antibacterial activity that, in some cases, was comparable to that of 0.2% chlorhexidine. Zones of inhibition were seen for the resin materials of Scotchbond 2 and Tripton with Streptococcus mutans, Streptococcus sanguis and Actinomyces viscosus. No inhibition was seen after these resins were cured, whereas the antibacterial effect of XR-Bond on S sanguis and A viscosus was not affected by light curing.
authors.affiliation: Department of Cariology, University of Göteborg, Faculty of Odontology, Sweden.
authors.forename: C G
authors.initials: CG
authors.lastname: Emilson
authors.forename: G
authors.initials: G
authors.lastname: Bergenholtz
mesh_terms: D016924:Actinomyces viscosus / Q000187:drug effects*; D000891:Anti-Infective Agents, Local / Q000494:pharmacology; D015169:Colony Count, Microbial; D003188:Composite Resins / Q000494:pharmacology*; D017220:Dentin-Bonding Agents / Q000494:pharmacology*; D005976:Glutaral / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007780:Lacticaseibacillus casei / Q000187:drug effects*; D008689:Methacrylates / Q000494:pharmacology; D011109:Polymethacrylic Acids / Q000494:pharmacology; D011140:Polyurethanes / Q000494:pharmacology; D019279:Resin Cements; D013291:Streptococcus / Q000187:drug effects*
chemical_list: D000891:Anti-Infective Agents, Local; D003188:Composite Resins; C080827:Denthesive; D017220:Dentin-Bonding Agents; D008689:Methacrylates; D011109:Polymethacrylic Acids; D011140:Polyurethanes; D019279:Resin Cements; C083372:Superlux Universal Bond 2; C069300:Tripton resin; C062652:Prisma Universal Bond; C067788:scotchbond 2; C070604:XR Bond; C044372:Gluma; D005976:Glutaral