Herpes simplex type 1 encephalitis in acquired immunodeficiency syndrome.
A severe acute necrotizing herpes simplex virus type 1 encephalitis, apparently mediated by macrophages or cytokines or both, was seen in a patient with acquired immunodeficiency syndrome. The necrosis had a distribution similar to that seen in immunocompetent subjects. Viral inclusions were abundant and meningeal reaction was minimal, as previously described in one anergic patient.
Tan
S V
SV
Department of Neurology, Westminster Hospital, London.
Guiloff
R J
RJ
Scaravilli
F
F
Klapper
P E
PE
Cleator
G M
GM
Gazzard
B G
BG
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000473:pathology*; D000328:Adult; D004279:DNA, Viral / Q000134:cerebrospinal fluid; D004660:Encephalitis / Q000150:complications / Q000473:pathology*; D006561:Herpes Simplex / Q000150:complications / Q000473:pathology*; D018259:Herpesvirus 1, Human / Q000235:genetics; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D016133:Polymerase Chain Reaction
D004279:DNA, Viral