[2,8 dihydroxyadenine(2,8 DHA) lithiasis. Report of 3 cases].
Presentation of three cases of 2,8 dihydroxyadenine calculi. This is an infrequent but potentially serious form of lithiasis, of purinic origin, caused by a genetic abnormality (deficit of adenine phosphoribosyltransferase, APRT) affecting both sexes. Frequent confusion of this form with uric lithiasis forces to try the use of IR spectrum or X-ray diffraction. Long-term follow-up of these patients and treatment with allopurinol, avoiding alkalinizating agents, is essential.
Wuhl
O
O
Servicio de Urología, Fundación Puigvert, Barcelona.
Vila
R
R
Barcelo
P
P
Laguna
P
P
Rousaud
A
A
D000225:Adenine / Q000031:analogs & derivatives* / Q000032:analysis; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D011687:Purines / Q000378:metabolism; D014545:Urinary Calculi / Q000737:chemistry* / Q000175:diagnosis / Q000209:etiology / Q000235:genetics / Q000378:metabolism / Q000628:therapy
D011687:Purines; C002993:2,8-dihydroxyadenine; D000225:Adenine
Litiasis de 2,8 dihidroxiadenina (2,8 DHA). A próposito de tres casos.