title: Photochemical decomposition of organic compounds in water after UV-irradiation: investigation of positive mutagenic effects.
abstract: It should be investigated whether UV-disinfection of natural and contaminated organic substances in surface and drinking water may generate a positive mutagenic effect. Selected organic pesticides (atrazine, simazine, metobromurone, methabenzthiazurone, dichlorprop) and organic compounds naturally present in water (phenylalanine, tyrosine, polysaccharides) were examined in Ames-test (bacterial strains TA 98 and TA 100) and sister chromatid exchange (SCE)-test (V79 cells) before and after UV-irradiation. UV-irradiation with low- and high-pressure mercury vapor lamps was carried out in parallel experiments. Based on results in Ames- and SCE-test a mutagenic activity was not obtained for all samples, neither before nor after UV-irradiation.
authors.affiliation: Institute for Hygiene, Free University of Berlin, Klinikum Charlottenburg, Germany.
authors.forename: I
authors.initials: I
authors.lastname: de Veer
authors.forename: H J
authors.initials: HJ
authors.lastname: Moriske
authors.forename: H
authors.initials: H
authors.lastname: Rüden
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D003412:Cricetulus; D004203:Disinfection / Q000379:methods; D009152:Mutagenicity Tests; D009153:Mutagens / Q000737:chemistry* / Q000633:toxicity*; D010575:Pesticides / Q000737:chemistry* / Q000633:toxicity*; D010777:Photochemistry; D012854:Sister Chromatid Exchange / Q000528:radiation effects; D014466:Ultraviolet Rays; D014874:Water Pollutants, Chemical / Q000633:toxicity*; D014876:Water Pollution; D014881:Water Supply
chemical_list: D009153:Mutagens; D010575:Pesticides; D014874:Water Pollutants, Chemical