title: [The enzyme systems in natural populations of the housefly Musca domestica highly resistant to organophosphate insecticides].
abstract: Two natural population of house flies from the Podol'sk District, Moscow Province have been studied. The both natural populations proved to be highly resistant to organophosphorus insecticides and sensitive to pyrethroids. The activity of esterases and glutathione-S-transferase has been studied, as well as the sensitivity of the enzymes of esterase complex in vitro to TBTP, DDVP and paraoxon, as compared with that of the sensitive strain SRS. Reliable differences have been established in the sensitivity of non-specific esterases to organophosphorus compounds. The esterase spectrum of enzymes from heads and abdomens of house flies has been studied by electrophoresis in PAAG and the zones of esterase activity have been revealed in the presence of two substrates: 2-HA and ATX. Differences in the activity of catecholamine esterase and cholinesterase and inn the sensitivity of cholinesterase from the natural populations to organophosphorus compounds have been established.
authors.forename: S A
authors.initials: SA
authors.lastname: Roslavtseva
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Eremina
authors.forename: E I
authors.initials: EI
authors.lastname: Bakanova
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Poliakova
mesh_terms: D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D004950:Esterases / Q000032:analysis / Q000187:drug effects; D005982:Glutathione Transferase / Q000032:analysis / Q000187:drug effects; D006793:Houseflies / Q000201:enzymology*; D007305:Insecticide Resistance; D007306:Insecticides; D009943:Organophosphorus Compounds; D011722:Pyrethrins; D012426:Russia; D013379:Substrate Specificity / Q000187:drug effects
chemical_list: D007306:Insecticides; D009943:Organophosphorus Compounds; D011722:Pyrethrins; D005982:Glutathione Transferase; D004950:Esterases
vernacular_title: Izuchenie nekotorykh fermentnykh sistem u prirodnykh populiatsiĭ komnatnykh mukh Musca domestica, vysokorezistentnykh k fosfororganicheskim insektitsidam.