title: [Disclosure of systemic lupus erythematosus in a case of hepatitis caused by ibuprofen].
abstract: We report the case of an hepatitis induced by ibuprofen in a young 32 years old woman, which allowed to discover an until then unknown systemic lupus erythematosus. After an analysis of the data of the literature, we are able to estimate at more than a 50% the specificity of the above mentioned induced effect of this drug for the diagnosis of lupus. Thus, non only a meningitis, but also an hepatitis induced by the ibuprofen need a systematic research of a connective tissue disease.
authors.affiliation: Service de médecine interne, hôpital de la Croix Saint-Simon, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Vigouroux
authors.forename: D
authors.initials: D
authors.lastname: Fitoussi
authors.forename: D
authors.initials: D
authors.lastname: Cariou
authors.forename: J
authors.initials: J
authors.lastname: Aerts
authors.forename: P
authors.initials: P
authors.lastname: Pasquier
mesh_terms: D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis*
chemical_list: D007052:Ibuprofen
vernacular_title: Découverte d'un lupus érythémateux disséminé à l'occasion d'une hépatite à l'ibuprofène.