Some features on RNA folding structures of cytochrome c oxidase subunit II and cytochrome P450.
We have defined the folding index of the RNA secondary structure and compared the value of this index obtained from a given RNA molecule with one from the random sequences with the same A, U, G, C ratio. The mRNA of the cytochrome c oxidase subunit II and cytochrome P450 from various species was analyzed. We found that the mRNA of these genes were more folded than the random sequences and the coding regions of these mRNA were as equally folded as the random sequences. This result suggests that the coding region of these mRNA has no more important secondary structure than have the random sequences with the same A, U, G, C ratio.
Arakawa
E
E
Department of Bacteriology, Medical School, University of Tokyo.
Yoshikura
H
H
Yamamoto
K
K
D000818:Animals; D001482:Base Composition; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D003576:Electron Transport Complex IV / Q000235:genetics*; D005069:Evaluation Studies as Topic; D006801:Humans; D009690:Nucleic Acid Conformation; D012333:RNA, Messenger / Q000737:chemistry* / Q000235:genetics*; D012984:Software; D012985:Software Design; D013045:Species Specificity
D012333:RNA, Messenger; D003577:Cytochrome P-450 Enzyme System; D003576:Electron Transport Complex IV