title: Radiofrequency catheter ablation of idiopathic left ventricular tachycardia: further evidence for microeentry as the underlying mechanism.
abstract: BACKGROUND
  Idiopathic left ventricular tachycardia with a QRS pattern of right bundle branch block and left-axis deviation constitutes a rare but electrophysiologically distinct arrhythmia entity. The underlying mechanism of this tachycardia, however, is still a matter of controversy. This report describes findings in a 42-year-old man who underwent successful radiofrequency catheter ablation of idiopathic left ventricular tachycardia.
  
  
  RESULTS
  On electrophysiologic study, the tachycardia was reproducibly induced and terminated with double ventricular extrastimuli. Intravenous verapamil terminated the tachycardia whereas adenosine did not. Detailed left ventricular catheter mapping during sinus rhythm revealed a fragmented delayed potential at the mid-apical region of the inferior site near the posterior fascicle of the left bundle branch. At the same site, continuous electrical activity throughout the entire cardiac cycle was recorded during ventricular tachycardia. Repeated spontaneous termination of this continuous electrical activity in late diastole was followed immediately by termination of the tachycardia. Single application of radiofrequency current for 20 seconds at this site completely abolished inducibility of the tachycardia. After catheter ablation, at the identical site of preablation recording of the fractionated potential during sinus rhythm, no fragmented delayed activity could be recorded. There was no complication from the ablation procedure.
  
  
  CONCLUSIONS
  The preablation recordings of fragmented delayed potentials during sinus rhythm and continuous diastolic electrical activity during tachycardia, together with ablation characteristics and previously reported electrophysiologic properties of this arrhythmia, may further support microreentry as the underlying mechanism in idiopathic left ventricular tachycardia.
authors.affiliation: Department of Cardiology and Angiology, Hospital of the Westfälische Wilhelms-University, Münster, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Kottkamp
authors.forename: X
authors.initials: X
authors.lastname: Chen
authors.forename: G
authors.initials: G
authors.lastname: Hindricks
authors.forename: S
authors.initials: S
authors.lastname: Willems
authors.forename: M
authors.initials: M
authors.lastname: Borggrefe
authors.forename: G
authors.initials: G
authors.lastname: Breithardt
mesh_terms: D000328:Adult; D001283:Atrioventricular Node / Q000503:physiopathology; D017115:Catheter Ablation; D004562:Electrocardiography; D004594:Electrophysiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012848:Sinoatrial Block / Q000503:physiopathology; D017180:Tachycardia, Ventricular / Q000503:physiopathology / Q000601:surgery*; D014700:Verapamil / Q000494:pharmacology
chemical_list: D014700:Verapamil