Coulometric determination of some antiinflammatory compounds.
A method is presented for the chlorocoulometric assay of small amounts of piroxicam and tenoxicam. This assay is carried out directly by coulometrically titrating the investigated substances with electrogenerated chloride in the presence of methyl orange as indicator. Results are accurate and reproducible. The method can be applied for routine analysis of these substances.
Nikolic
K
K
Institute of Organic Chemistry, Faculty of Pharmacy, Belgrade, Vojvode Stepe, Yugoslavia.
Bogavac
M
M
Arsenijevic
L
L
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D001391:Azo Compounds; D002214:Capsules; D004563:Electrochemistry; D009682:Magnetic Resonance Spectroscopy; D010894:Piroxicam / Q000031:analogs & derivatives / Q000032:analysis; D013055:Spectrophotometry, Infrared; D013488:Suppositories; D013607:Tablets
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001391:Azo Compounds; D002214:Capsules; D013488:Suppositories; D013607:Tablets; D010894:Piroxicam; C100258:methyl orange; C032801:tenoxicam