title: Late recurrent metastasis in Wilms' tumour.
abstract: Recurrence of Wilms' tumour after 5 years of disease-free survival is rare. We present the case of a 26-year-old man who had been diagnosed of Wilms' tumour at the age of 6 years treated by surgery, chemotherapy, and radiotherapy and who remained disease free for 8 years, after which lung metastases were detected. Second complete remission was attained with surgery and chemotherapy and 20 years after initial diagnosis he again presented with lung metastases, similarly achieving complete remission with surgery and second-line chemotherapy. The clinical and biological aspects of late metastasis in this neoplasm are discussed.
authors.affiliation: Unit of Oncología Pediátrica, Hospital Universitario Materno-Infantil Vall d'Hebron, Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Gallego-Melcón
authors.forename: J
authors.initials: J
authors.lastname: Sánchez de Toledo
authors.forename: D
authors.initials: D
authors.lastname: Doste
authors.forename: D
authors.initials: D
authors.lastname: López
authors.forename: F
authors.initials: F
authors.lastname: Moraga
authors.forename: C
authors.initials: C
authors.lastname: Rodríguez
authors.forename: T
authors.initials: T
authors.lastname: Vidal
authors.forename: J
authors.initials: J
authors.lastname: Bellmunt
mesh_terms: D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D012074:Remission Induction; D013997:Time Factors; D009396:Wilms Tumor / Q000473:pathology*