[The cerebral vasoconstrictor effects of malondialdehyde].
Malonic dialdehyde has a pronounced central vasoconstrictor effect, though when given in large doses, it causes a profound decrease in systemic blood pressure, however its vasoconstrictor effects are not directly related to fluctuations in systemic blood pressure. The universal antioxidant alpha-tocopherol acetate abolishes and prevents the central vasoconstrictor effects of malonic dialdehyde.
Mirzoian
S A
SA
Mkrtchian
S L
SL
Manukian
A A
AA
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D002536:Cerebral Arteries / Q000187:drug effects*; D002560:Cerebrovascular Circulation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006339:Heart Rate / Q000187:drug effects; D008315:Malondialdehyde / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D014662:Vasoconstrictor Agents / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D014810:Vitamin E / Q000494:pharmacology
D014662:Vasoconstrictor Agents; D014810:Vitamin E; D008315:Malondialdehyde
Tserebral'nye vazokonstriktornye éffekty malonovogo dial'degida.