[Cytokines, their receptors and inhibitors. Importance in laboratory diagnosis of rheumatoid arthritis].
The present paper reviews the literature on biological activities of human cytokines in homeostasis, as modulated by their secretion, expression of membrane-bound and soluble receptors as well as by means of other cytokines and specific inhibitors, respectively. The role of structure and properties of interleukins 1, 2, 6 and their receptors in pathophysiology and laboratory diagnostics of rheumatoid arthritis, is discussed. Methods of quantitative determination of cytokines are described.
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Zakład Biochemii Farmaceutycznej Akademii Medycznej, Wrocławiu.
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D001172:Arthritis, Rheumatoid / Q000175:diagnosis*; D016207:Cytokines / Q000502:physiology / Q000627:therapeutic use; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D007375:Interleukin-1 / Q000032:analysis; D007376:Interleukin-2 / Q000032:analysis; D015850:Interleukin-6 / Q000032:analysis
D016207:Cytokines; D007375:Interleukin-1; D007376:Interleukin-2; D015850:Interleukin-6
Cytokiny, ich receptory i inhibitory. Znaczenie w diagnostyce laboratoryjnej reumatoidalnego zapalenia stawów.