title: The efficacy of injectable and pour-on formulations of moxidectin against lice on cattle.
abstract: The efficacy of one administration of moxidectin against natural infestations of the 3 common species of cattle lice in Australia: Linognathus vituli, Damalinia bovis and Haematopinus eurysternus, was determined. A high degree of control of L vituli (the long-nosed sucking louse) was achieved with both the cattle injection (96.7% and 100%) at 0.2 mg/kg and the cattle pour-on formulation (94.6% and 100%) at 0.5 mg/kg on the 2 farms where this louse occurred. An injection of moxidectin at 0.2 mg/kg did not eliminate D bovis. In these trials efficacy ranged from nil to 85.2%. In contrast the pour-on formulation at 0.5 mg/kg provided consistently high efficacy (83.6 to 100%) against D bovis on 3 farms. Infestations of H eurysternus (the short-nosed sucking louse) were low and no significant difference was recorded between treatment groups in a single trial, however, lice persisted on 3 to 7 cattle in the untreated group at each inspection, whereas none were found on any animals in the 2 groups treated with moxidectin on inspection after treatment.
authors.affiliation: Veterinary Health Research Pty Ltd, Armidale, New South Wales.
authors.forename: B
authors.initials: B
authors.lastname: Chick
authors.forename: D
authors.initials: D
authors.lastname: McDonald
authors.forename: R
authors.initials: R
authors.lastname: Cobb
authors.forename: P J
authors.initials: PJ
authors.lastname: Kieran
authors.forename: I
authors.initials: I
authors.lastname: Wood
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000854:Anoplura; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000517:prevention & control; D005260:Female; D007279:Injections, Subcutaneous / Q000662:veterinary; D007306:Insecticides / Q000008:administration & dosage / Q000627:therapeutic use*; D010373:Lice Infestations / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D018942:Macrolides; D008297:Male; D008003:Phthiraptera
chemical_list: D000900:Anti-Bacterial Agents; D007306:Insecticides; D018942:Macrolides; C027837:moxidectin