title: Acute aortic occlusion. A 40-year experience.
abstract: OBJECTIVE
  To review a large experience with acute aortic occlusion (AAO) to better define the cause, clinical presentation, treatment, prognostic variables, and outcome.
  
  
  METHODS
  Retrospective review of 46 consecutive patients with AAO during a 40-year period.
  
  
  METHODS
  A large urban tertiary care referral center in Detroit, Mich.
  
  
  METHODS
  Adult patients with arteriographic and/or operative confirmation of acute occlusion of the abdominal aorta plus signs and symptoms of acute ischemia.
  
  
  METHODS
  Operative and nonoperative treatment of AAO.
  
  
  METHODS
  Mortality, morbidity, and long-term survival. Other variables measured included cause, risk factors, and effects of duration and severity of ischemia and treatment methods on outcome.
  
  
  RESULTS
  Two primary causes were identified--embolism (65%) and thrombosis (35%). Heart disease and female gender were risk factors for embolism, while smoking and diabetes were risk factors for thrombosis. Severity of ischemia on presentation correlated better with outcome than duration of ischemia. The hospital mortality rate was 35% and morbidity, 74%, with no difference between the two groups. Recurrent arterial embolism occurred in 43% of patients with embolic AAO. Seventy-two percent of AAO survivors were alive 5 years after therapy.
  
  
  CONCLUSIONS
  Acute aortic occlusion remains a serious vascular surgical emergency with significant morbidity and mortality, even when recognized promptly and treated appropriately. Nevertheless, survivors have a reasonable long-term outcome. Permanent anticoagulation is suggested in patients with embolic AAO to minimize a high incidence of recurrent arterial embolism.
authors.affiliation: Department of Surgery, Henry Ford Hospital, Detroit, Mich.
authors.forename: C D
authors.initials: CD
authors.lastname: Dossa
authors.forename: A D
authors.initials: AD
authors.lastname: Shepard
authors.forename: D J
authors.initials: DJ
authors.lastname: Reddy
authors.forename: C M
authors.initials: CM
authors.lastname: Jones
authors.forename: J P
authors.initials: JP
authors.lastname: Elliott
authors.forename: R F
authors.initials: RF
authors.lastname: Smith
authors.forename: C B
authors.initials: CB
authors.lastname: Ernst
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D001012:Aorta, Abdominal; D001018:Aortic Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy*; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy*; D003327:Coronary Disease / Q000150:complications / Q000453:epidemiology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000453:epidemiology; D004617:Embolism / Q000150:complications; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011859:Radiography; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D015996:Survival Rate; D013927:Thrombosis / Q000150:complications; D013997:Time Factors; D016896:Treatment Outcome