title: Primary rhabdomyosarcoma of the iliac bone in an adult: a case mimicking fibrosarcoma.
abstract: Primary rhabdomyosarcoma of bone is exceedingly rare. We present a case of rhabdomyosarcoma of the iliac bone in a 32-year-old male. Histologically, the tumour consisted mainly of a uniform proliferation of elongated spindle cells arranged in a herring bone pattern, simulating fibrosarcoma. Focally there was a conventional embryonal pattern with scattered rhabdomyoblasts possessing an eosinophilic cytoplasm. Immunohistochemical studies disclosed expression of muscle markers such as desmin and muscle-specific actin, in both the embryonal and spindle-cell areas and myoglobin only in the embryonal areas. Such histological features are unusual for classical embryonal rhabdomyosarcoma. The anatomical site and age of the patient are also atypical.
authors.affiliation: Second Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Oda
authors.forename: M
authors.initials: M
authors.lastname: Tsuneyoshi
authors.forename: H
authors.initials: H
authors.lastname: Hashimoto
authors.forename: T
authors.initials: T
authors.lastname: Iwashita
authors.forename: M
authors.initials: M
authors.lastname: Ushijima
authors.forename: S
authors.initials: S
authors.lastname: Masuda
authors.forename: Y
authors.initials: Y
authors.lastname: Iwamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Sugioka
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005354:Fibrosarcoma / Q000175:diagnosis*; D006801:Humans; D007085:Ilium / Q000000981:diagnostic imaging / Q000473:pathology; D007124:Immunoenzyme Techniques; D008297:Male; D011859:Radiography; D012208:Rhabdomyosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D000911:Antibodies, Monoclonal