title: Dietary modifications versus dicyclomine hydrochloride in the treatment of severe infantile colics.
abstract: This study examined 120 infants, aged 3-12 weeks, with severe colics and compared the results of a specific hypoallergenic diet (group A) with those of pharmacological treatment (group B). Non-breast-fed group A infants received soy milk and if unresponsive, hydrolyzed milk formulas; mothers of breast-fed infants received a diet without cow's milk, eggs or fish. Breast-fed and non-breast-fed group B infants received dicyclomine hydrochloride 3 mg/kg/day. Results, based on quantitative measurements of crying, indicated that in breast-fed infants there was no significant improvement between group A (62.5%) and group B (66.6%) infants. Among formula-fed infants, comparison of positive results using soy milk (65.9%) with positive results using dicyclomine (53.3%) was not significant; positive results using soy milk and hydrolyzed milk formulas in non-responders to soy milk, provided an improvement in 95.4% of cases. Pharmacological treatment provided an improvement in 53.3% of cases. The difference was significant (p < 0.01).
authors.affiliation: Institute of Pediatrics, University Hospital, Turin, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Oggero
authors.forename: G
authors.initials: G
authors.lastname: Garbo
authors.forename: F
authors.initials: F
authors.lastname: Savino
authors.forename: M
authors.initials: M
authors.lastname: Mostert
mesh_terms: D001942:Breast Feeding; D003085:Colic / Q000178:diet therapy* / Q000188:drug therapy* / Q000209:etiology; D004025:Dicyclomine / Q000627:therapeutic use*; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000517:prevention & control; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D008297:Male; D008895:Milk, Human; D013025:Glycine max
chemical_list: D004025:Dicyclomine