title: Reproductive failure in sows following experimental infection with a Belgian EMCV isolate.
abstract: In this study, a transplacental infection with fetal death was demonstrated following inoculation of pregnant sows with a Belgian encephalomyocarditis virus (EMCV) isolate. Eight multiparus sows were inoculated between 60 and 92 days of gestation with this EMCV-isolate to investigate its ability to cause reproductive failure in sows. Virus persistence and antibody titre in their offspring were also studied. Only the two sows inoculated at 60 days of gestation showed premature farrowing, but all sows seroconverted to EMCV. Virus was recovered from the offspring of all sows at the time of farrowing, but not from every piglet born. One month after birth EMCV could be isolated from all the piglets examined. These results can help in a better understanding of the spread of the disease in piggeries.
authors.affiliation: Nationaal Instituut voor Diergeneeskundig Onderzoek (NIDO-INRV), Ukkel,Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Koenen
authors.forename: K
authors.initials: K
authors.lastname: De Clercq
authors.forename: J
authors.initials: J
authors.lastname: Lefebvre
authors.forename: R
authors.initials: R
authors.lastname: Strobbe
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001530:Belgium; D018188:Cardiovirus Infections / Q000150:complications / Q000382:microbiology / Q000662:veterinary*; D004686:Encephalomyocarditis virus / Q000276:immunology / Q000472:pathogenicity*; D005260:Female; D005313:Fetal Death / Q000382:microbiology / Q000662:veterinary*; D006321:Heart / Q000196:embryology / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology / Q000662:veterinary*; D013154:Spleen / Q000196:embryology / Q000382:microbiology; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*
chemical_list: D000914:Antibodies, Viral