[Evaluation of the Vidas system for the serological diagnosis of toxoplasmosis].
The recent immuno-analysis system Vidas (bioMérieux) for the serological diagnosis of toxoplasmosis was compared to the Abbott Toxo EIA system, taking the indirect immunofluorescence assay (IFA) as reference for immunoglobulin G and the immunosorbent agglutination assay (ISAGA) for immunoglobulin M. Five hundred and ninety-four individual sera and 15 seroconversions or recent infections (39 sera) were studied. Sensitivity and specificity of the Vidas system were respectively 99.7% and 99.4% for IgG, and 100% and 97% for IgM. During primary toxoplasmia infection, the Vidas system allows very early detection of the appearance of IgM and IgG. The Vidas Toxo IgG is more sensitive than the Abbott G EIA. For IgM, the Vidas Toxo M is less specific but much more sensitive than the Abbott M EIA.
Pelloux
H
H
Service de parasitologie, CHU de Grenoble, France.
Ciapa
P
P
Goullier-Fleuret
A
A
Ambroise-Thomas
P
P
D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D014125:Toxoplasmosis, Congenital / Q000175:diagnosis* / Q000276:immunology
D007074:Immunoglobulin G; D007075:Immunoglobulin M
Evaluation du système Vidas pour le diagnostic sérologique de la toxoplasmose.