[Bouginage of peptic esophageal stenoses. Results of one year with long-term omeprazole medication].
METHODS
Within the framework of an open prospective study, 47 patients with chronic reflux esophagitis, unresponsive to H2-receptor blockers and complicated by stenosis, underwent endoscopic bougienage. Unsuccessful treatment with H2-receptor blockers was followed in all patients by antisecretion treatment with omeprazole at a dose of 40 mg/day.


RESULTS
At the latest after 3 months, stenotic and inflammatory changes had cleared up in all patients and under continued omeprazole over the long-term, remission of at least one year was achieved.


CONCLUSIONS
A combination of endoscopic bougienage and simultaneous treatment with the proton pump blocker, omeprazole, represents effective treatment of chronic reflux disease complicated by stenosis.
Jaspersen
D
D
Medizinische Klinik II, Städtisches Klinikum, Fulda.
Körner
T
T
Schorr
W
W
Hammar
C H
CH
Blaurock
M
M
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004106:Dilatation / Q000295:instrumentation*; D004940:Esophageal Stenosis / Q000628:therapy*; D004942:Esophagitis, Peptic / Q000628:therapy*; D020701:Esophagoscopes; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D009853:Omeprazole / Q000008:administration & dosage*; D011446:Prospective Studies
D009853:Omeprazole
Bougierung peptischer Osophagusstenosen. Ein-Jahres-Resultate unter Dauermedikation mit Omeprazol.