title: Identification and analysis of the transport/capsid assembly protein (tp/cap) gene of human herpesvirus-6 (HHV6).
abstract: The transport/capsid assembly protein (tp/cap) gene of human herpesvirus 6 (HHV6) strain U1102 has been identified and localized on the restriction enzyme map of the viral genome, to the EcoRI-Q fragment. The complete DNA sequence of the tp/cap gene was determined. The tp/cap gene encodes a protein product of 726 amino acids and has the strongest similarity with the homologous gene (HCMV UL56) from HCMV. Upstream of the tp/cap open reading frame is the gene for the major DNA binding protein (mdbp) and downstream is the glycoprotein B (gB) gene. This gene block arrangement is common to all herpesviruses.
authors.affiliation: Department of Virology, Royal Postgraduate Medical School, London, United Kingdom.
authors.forename: M D
authors.initials: MD
authors.lastname: Jones
authors.forename: I A
authors.initials: IA
authors.lastname: Teo
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003062:Codon / Q000235:genetics; D016384:Consensus Sequence; D017931:DNA Primers; D004268:DNA-Binding Proteins / Q000235:genetics; D005814:Genes, Viral; D016679:Genome, Viral; D015654:Herpesvirus 6, Human / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D016133:Polymerase Chain Reaction; D015183:Restriction Mapping; D017386:Sequence Homology, Amino Acid; D014764:Viral Proteins / Q000235:genetics*
chemical_list: D003062:Codon; D017931:DNA Primers; D004268:DNA-Binding Proteins; D014764:Viral Proteins; C083787:transport-capsid assembly protein, Human herpesvirus 6