Defective monocyte chemotaxis in patients with epidermoid tumors of the head and neck.
Monocyte chemotactic activity was assayed by a modified Boyden-Chamber method using the chemoattractant casein and was found to be impaired in 13 patients with epidermoid tumors of the head and neck. Using 7 healthy subjects as controls, the depression in both monocyte chemotactic activity and monocyte random migration in the patients with tumors was found to be statistically significant by the "leading front" technique (P < 0.05).
Güngör
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A
Department of Otolaryngology, Head and Neck Surgery, Hacettepe University, Ankara, Turkey.
Yetgin
S
S
Sözeri
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B
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000503:physiopathology*; D002465:Cell Movement; D002634:Chemotaxis, Leukocyte; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000502:physiology*; D009959:Oropharyngeal Neoplasms / Q000503:physiopathology