Risk factors for HIV-1 and HIV-2 infection in pregnant women in Dakar, Senegal.
This study examines the prevalence and risk factors for Human Immunodeficiency Virus type 1 (HIV-1) and type 2 (HIV-2) infection in pregnant women in Dakar, Senegal. From April 1991 to January 1993, 9,518 pregnant women were interviewed and serologically tested for antibodies to HIV-1 and HIV-2; 26 (0.3%) were HIV-1 seropositive, 44 (0.5%) were HIV-2 seropositive, two (0.02%) were dually seropositive, and 9,448 (99.3%) were seronegative. Guinea-Bissau nationality and age > 25 years were associated with HIV-2 infection, whereas parity < or = 2 was associated with HIV-1 infection. Among women who gave birth to live infants, shorter length of union with the partner and having been married more than once were associated with HIV-2 infection, whereas age < or = 25 years was associated with HIV-1 infection. Information gained by this study may help target intervention strategies for preventing maternal HIV infection and understanding biological differences between the two viruses.
Abbott
R C
RC
Department of Cancer Biology, Harvard School of Public Health, Boston, Massachusetts 02115.
NDour-Sarr
A
A
Diouf
A
A
NDoye
T
T
Bâ
D
D
Tall
N
N
MBaye
N
N
Kébé
F
F
Diadhiou
F
F
Essex
M E
ME
D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D005260:Female; D006169:Guinea-Bissau / Q000208:ethnology; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1 / Q000276:immunology; D015498:HIV-2 / Q000276:immunology; D006801:Humans; D015999:Multivariate Analysis; D010298:Parity; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012675:Senegal / Q000453:epidemiology; D012747:Sexual Partners; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
D015483:HIV Antibodies