title: US contrast enhancement with intra-arterial CO2 injection in the staging of hepatocellular carcinomas.
abstract: Liver US contrast enhancement was obtained with the intrahepatic arterial injection of CO2 in 45 hepatocellular carcinoma patients. Before digital subtraction angiography (DSA) all the patients underwent conventional US and CT of the liver; 20 patients also underwent CT during arterial portography (CTAP). Liver US contrast enhancement with CO2 exhibited the same sensitivity as DSA (92%) in demonstrating hypervascular HCCs and proved superior to the other diagnostic procedures -- 85% for CT and 78% for conventional US. DSA combined with echocarbography, with its 2D demonstration of liver anatomy, improved the correct staging of HCCs, for better treatment planning.
authors.affiliation: Istituto Nazionale Tumori, Radiologia Interventistica, Milano.
authors.forename: F
authors.initials: F
authors.lastname: Garbagnati
authors.forename: M
authors.initials: M
authors.lastname: Milella
authors.forename: C
authors.initials: C
authors.lastname: Spreafico
authors.forename: A
authors.initials: A
authors.lastname: Marchianò
authors.forename: L F
authors.initials: LF
authors.lastname: Frigerio
authors.forename: G
authors.initials: G
authors.lastname: Di Tolla
authors.forename: G
authors.initials: G
authors.lastname: Patelli
authors.forename: R
authors.initials: R
authors.lastname: Lanocita
mesh_terms: D000792:Angiography; D002245:Carbon Dioxide / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods
chemical_list: D003287:Contrast Media; D002245:Carbon Dioxide