Mechanisms of pancreatic B-cell dysfunction and glucose toxicity in non-insulin-dependent diabetes.
Flatt
P R
PR
Department of Biological and Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland, U.K.
Barnett
C R
CR
Swanston-Flatt
S K
SK
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001341:Autonomic Nervous System / Q000503:physiopathology; D002118:Calcium / Q000378:metabolism; D002237:Carbohydrate Dehydrogenases / Q000378:metabolism; D003285:Contractile Proteins / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics / Q000378:metabolism / Q000503:physiopathology*; D005941:Glucokinase / Q000378:metabolism; D005947:Glucose / Q000633:toxicity*; D051273:Glucose Transporter Type 2; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000096:biosynthesis / Q000378:metabolism; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology*; D008928:Mitochondria / Q000201:enzymology; D009004:Monosaccharide Transport Proteins / Q000378:metabolism; D015221:Potassium Channels / Q000502:physiology
D003285:Contractile Proteins; D051273:Glucose Transporter Type 2; D007328:Insulin; D009004:Monosaccharide Transport Proteins; D015221:Potassium Channels; D000255:Adenosine Triphosphate; D002237:Carbohydrate Dehydrogenases; C056470:3-glycerophosphate dehydrogenase; D005941:Glucokinase; D005952:Glucose-6-Phosphatase; D005947:Glucose; D002118:Calcium