Assessment of anthracycline cardiomyopathy by endomyocardial biopsy.
Ultrastructural evaluation of endomyocardial biopsy specimens is a sensitive and effective method with which to detect and quantitate cardiotoxicity produced by anthracylines. The procedure and grading system used at the M.D. Anderson Cancer Center are described, and some of the pitfalls that may be encountered by the electron microscopist are reviewed.
Mackay
B
B
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Ewer
M S
MS
Carrasco
C H
CH
Benjamin
R S
RS
D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008854:Microscopy, Electron; D009206:Myocardium / Q000473:pathology*; D012680:Sensitivity and Specificity
D000903:Antibiotics, Antineoplastic