Oncocytic hyperplasia in the human minor salivary glands: a post-mortem study.
Oncocytic hyperplasia in the human labial salivary glands was sought in a series of 217 post-mortem subjects. Oncocytic change occurred in 183 subjects and hyperplasia was found in 19 of those (the overall incidence being 8.8%), ranging in age from the third decade to the ninth. The sex distribution showed a significantly greater rate in males (16 of 139 males, 11.5%; 3 of 78 females, 3.8%). Oncocytic hyperplasia occurred in the duct system, and not in the acinar regions; it was frequently seen in the interlobular and intralobular ducts. Oncocytic hyperplasia was classified into four types; focal hyperplasia of the duct wall resulting in partial thickening of the duct wall; marked hyperplasia resulting in thickening of the duct wall, extending over half of the circumference; marked hyperplasia extending to the whole duct wall and intralobular adeno-tubular hyperplasia with or without cystic dilatation. About half of the subjects with oncocytic hyperplasia showed a few hyperplastic foci in one gland. The changes increased in severity in older subjects.
Takeda
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Department of Oral Pathology, School of Dentistry, Iwate Medical University, Japan.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002102:Cadaver; D002648:Child; D002675:Child, Preschool; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012470:Salivary Glands, Minor / Q000473:pathology*