[Treatment of keloids and hypertrophic scars. Pilot study with intralesional Lipotalon injections].
A pilot study was conducted to establish whether intralesional injection of a microsomal corticoid, Lipotalon, would reduce the development of keloids and hypertrophic scars. Thirteen patients with 17 scars and keloids were admitted to the study. In all the patients investigated, injection of Lipotalon into the lesion led to a moderate to appreciable improvement in the hypertrophic scars and keloids. Injections of 0.5 to 4 mg Lipotalon were given, for the most part, at intervals of 4 to 6 weeks, and were oriented to the respective findings. No side effects were observed. Some of the patients received topical application of Lipotalon as adjuvant treatment to surgical scar resection. Here, too, a trend towards positive results was observed, although in one case, disordered wound healing was seen.
Stark
G B
GB
Sektion für Plastische und Handchirurgie, Universitätsklinik Freiburg.
D000293:Adolescent; D000328:Adult; D002921:Cicatrix / Q000188:drug therapy*; D003907:Dexamethasone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004337:Drug Carriers; D005260:Female; D006801:Humans; D006984:Hypertrophy; D015552:Injections, Intralesional; D007627:Keloid / Q000188:drug therapy*; D008081:Liposomes; D008297:Male; D010865:Pilot Projects; D011446:Prospective Studies
D004337:Drug Carriers; D008081:Liposomes; D003907:Dexamethasone
Behandlung von Keloiden und hypertrophen Narben. Pilotstudie mit intraläsionären Lipotalon-Injektionen.