title: Effect of silica on the spontaneous cytotoxicity of axial organ cells from Asterias rubens.
abstract: Axial organ cells (A.O.) which are composed of phagocytes and lymphocytes from the sea star Asterias rubens exert a spontaneous cytotoxicity against mouse tumour cells. This toxicity was tested in the presence or absence of silica. It appears that phagocytes play the role of killer cells.
authors.affiliation: Department of Biology, University of Orleans, France.
authors.forename: M
authors.initials: M
authors.lastname: Leclerc
authors.forename: M
authors.initials: M
authors.lastname: Bajelan
authors.forename: R
authors.initials: R
authors.lastname: Barot
authors.forename: H
authors.initials: H
authors.lastname: Tlaskalova-Hogenova
mesh_terms: D000818:Animals; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D008221:Lymphoid Tissue / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D010586:Phagocytes / Q000187:drug effects* / Q000276:immunology; D010587:Phagocytosis / Q000187:drug effects; D012822:Silicon Dioxide / Q000494:pharmacology*; D013045:Species Specificity; D013215:Starfish / Q000187:drug effects / Q000276:immunology*
chemical_list: D007166:Immunosuppressive Agents; D012822:Silicon Dioxide