title: [A case of superficial hemosiderosis of the central nervous system with normal CSF findings and unknown source of bleeding].
abstract: A 65-year-old woman had suffered from slowly progressive hearing loss for one year. She had neither repeated episodes of headache or vomiting nor a past history of neurosurgical operation. Neurologic examination revealed moderate diminution in hearing, pyramidal tract sign and cerebellar ataxia without dementia. CSF was under normal pressure, clear and colorless, with total protein 35 mg/dl, glucose 59 mg/dl and a cell count of 2 WBC/mm3. T2-weighted images (TR200/TE80) of high-field MRI demonstrated marginal hypointensity of the brainstem, the Sylvian fissures and the entire spinal cord. Angiography of the cerebral vessels failed to identify the source of bleeding. To our knowledge, this is the first report of superficial hemosiderosis of the central nervous system with normal CSF findings and an unknown source of bleeding confirmed by MRI.
authors.affiliation: First Department of Internal Medicine, Nagasaki University School of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Tsuboi
authors.forename: K
authors.initials: K
authors.lastname: Ohishi
authors.forename: S
authors.initials: S
authors.lastname: Shirabe
authors.forename: M
authors.initials: M
authors.lastname: Tsujihata
authors.forename: S
authors.initials: S
authors.lastname: Nagataki
mesh_terms: D000368:Aged; D001927:Brain Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D002543:Cerebral Hemorrhage / Q000175:diagnosis*; D005260:Female; D006486:Hemosiderosis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging