Inactivation of the IGF-I gene in mice results in perinatal lethality.
Powell-Braxton
L
L
Genentech Inc., South San Francisco, California 94080.
Hollingshead
P
P
Giltinan
D
D
Pitts-Meek
S
S
Stewart
T
T
D000483:Alleles; D000818:Animals; D005314:Embryonic and Fetal Development / Q000235:genetics*; D005260:Female; D005786:Gene Expression Regulation; D007334:Insulin-Like Growth Factor I / Q000235:genetics*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains; D016254:Mutagenesis, Insertional; D010735:Phosphoglycerate Kinase / Q000235:genetics; D011247:Pregnancy; D011401:Promoter Regions, Genetic; D015183:Restriction Mapping
D007334:Insulin-Like Growth Factor I; D010735:Phosphoglycerate Kinase