[Polyglobulia and bronchopneumopathies: correlations of ferritin and other ferric parameters with various erythrocytic indexes].
In 15 patients with chronic bronchopneumopathy (7 with polyglobulia and 8 without it), we observed that polyglobulic patients had higher average levels of sideremia and basal saturation of transferrin and lower levels of HCM, CHCM and VCM. No significant differences were observed in the average levels of ferritin between both groups. Overall, in this series of 15 patients, a significant inverse correlation was observed between sideremia and HCM (r = -0.52; p < 0.05) and between sideremia and CHCM (r = -0.55, p < 0.5), as well as a trend towards a direct correlation between sideremia and the red blood cells count (r = 0.45, N.S.). There was also a direct correlation between serum ferritin and the sedimentation rate (r = 0.72, p < 0.01) and trends towards inverse correlations although not significant, between ferritin and sideremia (r = -0.25, N.S.). These data reflect a hyperconsumption of iron in the respiratory polyglobulia, with some relative deficit, suggesting as well that serum ferritin is not a good enough criteria in these cases for the evaluation of iron deposits, because it behaves like the sedimentation rate with respect to acute phase reactants when there is inflammation.
Sánchez Sánchez
M L
ML
Servicio de Medicina Interna I. Hospital Universitario de San Carlos, Facultad de Medicina, Universidad Complutense, Madrid.
Ciriza de los Ríos
C
C
Arroyo Vicente
M
M
Ortega de Heredia
D
D
Arroyo Ordóñez
M J
MJ
Rubio Pérez
P
P
D001799:Blood Sedimentation; D001982:Bronchial Diseases / Q000097:blood* / Q000150:complications; D002908:Chronic Disease; D004909:Erythrocyte Indices; D005293:Ferritins / Q000097:blood*; D006801:Humans; D007501:Iron / Q000097:blood*; D008171:Lung Diseases / Q000097:blood* / Q000150:complications; D008297:Male; D011086:Polycythemia / Q000097:blood* / Q000150:complications; D012131:Respiratory Insufficiency / Q000097:blood* / Q000150:complications
D005293:Ferritins; D007501:Iron
Poliglobulia y bronconeumopatías: correlaciones de la ferritina y otros parámetros férricos con diversos índices eritrocíticos.