title: A hypermetabolic reaction during anaesthesia and surgery. A case report.
abstract: A young man underwent anaesthesia and surgery after multiple fractures. After 2 hours of anaesthesia, the patient developed hypercapnia, acidosis, hyperpyrexia and mild muscle rigidity. He was treated for malignant hyperthermia. Muscle tension studies with caffeine-halothane and muscle histology proved normal. The differential diagnosis of this abnormal metabolic response is briefly discussed.
authors.affiliation: Department of Anaesthesia, Hillbrow Hospital, University of the Witwatersrand, Johannesburg.
authors.forename: D
authors.initials: D
authors.lastname: Hopkins
authors.forename: E A
authors.initials: EA
authors.lastname: Shipton
mesh_terms: D000328:Adult; D000768:Anesthesia, General / Q000009:adverse effects*; D006221:Halothane / Q000009:adverse effects; D006801:Humans; D008297:Male; D008305:Malignant Hyperthermia / Q000209:etiology*
chemical_list: D006221:Halothane