title: Genetics of signal transduction in invertebrates.
abstract: Receptor tyrosine kinases regulate a number of different cell fate decisions during invertebrate development. Genetic analysis of the signal transduction pathways activated by these kinases suggests that they converge upon a common pathway involving Ras and a cascade of cytoplasmic kinases, diverging again in the nucleus with the regulation of specific transcription factors.
authors.affiliation: Zoologisches Institut, Universität Zürich, Switzerland.
authors.forename: B
authors.initials: B
authors.lastname: Dickson
authors.forename: E
authors.initials: E
authors.lastname: Hafen
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002454:Cell Differentiation; D011905:Genes, ras; D007448:Invertebrates / Q000235:genetics* / Q000502:physiology*; D008969:Molecular Sequence Data; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics*
chemical_list: D020794:Receptor Protein-Tyrosine Kinases