title: Epileptogenic potential of antimalarial drugs.
abstract: Available clinical reports suggest that antimalarial drugs may cause epileptic seizures as an adverse reaction in susceptible individuals. Epileptic patients and others with a low seizure threshold appear particularly prone. Antimalarial drugs, particularly chloroquine and mefloquine, should be used with caution by patients with epilepsy.
authors.affiliation: Department of Medicine, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors.forename: B
authors.initials: B
authors.lastname: Adamolekun
mesh_terms: D000328:Adult; D015984:Causality; D002738:Chloroquine / Q000009:adverse effects*; D003906:Developing Countries; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D015767:Mefloquine / Q000009:adverse effects; D011796:Quinacrine / Q000009:adverse effects
chemical_list: D002738:Chloroquine; D011796:Quinacrine; D015767:Mefloquine