[Chronic urticaria-macroglobulinemia (Schnitzler syndrome): developing to IgM myeloma. Apropos of a case].
Schnitzler's syndrome has been described in 1972. It associates a chronic urticaria with leukocytoclastic vasculitis, a macroglobulinemia, bone pains, hyperostosis. In the twenty three cases reported, the evolution is benign but three patients including the princeps case developed a Waldenström's disease or a lymphoplasmocytic lymphoma. We present the case of one patient, aged 65, with Schnitzler's syndrome, who, after 6 years evolution, presents a IgM myeloma. Schnitzler's syndrome appeared as a pre-hemopathic state which has to be taken care of regularly and for a long time.
Govindaraju
S
S
Service de rhumatologie, CHU, hôpital Sébastopol, Reims, France.
Brochot
P
P
Ringot
A C
AC
Paternotte
L
L
Morrone
A
A
Eschard
J P
JP
Etienne
J C
JC
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D002699:Chlorambucil / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D007075:Immunoglobulin M; D008297:Male; D009101:Multiple Myeloma / Q000188:drug therapy / Q000209:etiology*; D013577:Syndrome; D013997:Time Factors; D014581:Urticaria / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology
D000305:Adrenal Cortex Hormones; D007075:Immunoglobulin M; D002699:Chlorambucil
Urticaire chronique-macroglobulinémie (syndrome de Schnitzler): évolution vers un myélome à IgM. A propos d'un cas.