title: Pregnancy after orthotopic continent urinary diversion.
abstract: Continent urinary diversion has become a common form of bladder management for the female exstrophy patient in whom primary reconstruction has failed. Reported are the results of successful pregnancies in four young adult females, who had previously undergone a flap vaginoplasty as part of earlier management and more recently a continent right colonic urinary reservoir with a perineal stoma (Indiana pouch). Pregnancy in each of these patients was characterized by several urinary tract infections, cervical prolapse and mild to severe maternal hydronephrosis. All of the patients had some degree of difficulty with clean intermittent catheterization. One patient required an indwelling catheter with prolonged bed rest. Maternal hydronephrosis resolved after delivery in all instances. All four patients delivered their infants by way of cesarean section, either emergently for maternal or fetal distress or electively. Cervical prolapse did not resolve in three patients and will require surgical repair. After delivery, all patients returned to their previous pattern of clean intermittent catheterization without loss of continence. All the infants delivered were healthy with appropriate weights and high Apgar scores (more than 8). Orthotopic (perineal stoma) continent urinary diversion is not a contraindication to pregnancy. However, our experience mandates delivery by cesarean section with close monitoring for maternal or fetal distress during gestation.
authors.affiliation: Department of Urology, College of Physicians and Surgeons, Columbia University, New York, New York.
authors.forename: W A
authors.initials: WA
authors.lastname: Kennedy
authors.forename: T W
authors.initials: TW
authors.lastname: Hensle
authors.forename: E A
authors.initials: EA
authors.lastname: Reiley
authors.forename: H E
authors.initials: HE
authors.lastname: Fox
authors.forename: T
authors.initials: T
authors.lastname: Haus
mesh_terms: D000328:Adult; D001746:Bladder Exstrophy / Q000601:surgery; D002585:Cesarean Section; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000453:epidemiology; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D011256:Pregnancy Outcome / Q000453:epidemiology*; D014547:Urinary Diversion; D016476:Urinary Reservoirs, Continent; D014552:Urinary Tract Infections / Q000453:epidemiology; D014596:Uterine Prolapse / Q000453:epidemiology