title: 3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic acid: a non-steroidal estrogen with functional selectivity for bone over uterus in rats.
authors.affiliation: Department of Medicinal Chemistry, Glaxo Research Institute, Research Triangle Park, NC 27709.
authors.forename: T M
authors.initials: TM
authors.lastname: Willson
authors.forename: B R
authors.initials: BR
authors.lastname: Henke
authors.forename: T M
authors.initials: TM
authors.lastname: Momtahen
authors.forename: P S
authors.initials: PS
authors.lastname: Charifson
authors.forename: K W
authors.initials: KW
authors.lastname: Batchelor
authors.forename: D B
authors.initials: DB
authors.lastname: Lubahn
authors.forename: L B
authors.initials: LB
authors.lastname: Moore
authors.forename: B B
authors.initials: BB
authors.lastname: Oliver
authors.forename: H R
authors.initials: HR
authors.lastname: Sauls
authors.forename: J A
authors.initials: JA
authors.lastname: Triantafillou
mesh_terms: D000179:Acrylates / Q000737:chemistry / Q000494:pharmacology*; D000469:Alkaline Phosphatase / Q000096:biosynthesis; D000818:Animals; D015519:Bone Density / Q000187:drug effects; D001842:Bone and Bones / Q000187:drug effects*; D002460:Cell Line; D002934:Cinnamates; D004790:Enzyme Induction / Q000187:drug effects; D004965:Estrogen Antagonists / Q000494:pharmacology; D004968:Estrogens, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology*; D005260:Female; D006801:Humans; D009929:Organ Size / Q000187:drug effects; D010052:Ovariectomy; D051381:Rats; D011960:Receptors, Estrogen / Q000737:chemistry / Q000187:drug effects / Q000502:physiology; D013267:Stilbenes / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D014599:Uterus / Q000033:anatomy & histology / Q000187:drug effects* / Q000201:enzymology
chemical_list: D000179:Acrylates; D002934:Cinnamates; D004965:Estrogen Antagonists; D004968:Estrogens, Non-Steroidal; D011960:Receptors, Estrogen; D013267:Stilbenes; C087550:3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid; D000469:Alkaline Phosphatase