Transcatheter patent ductus arteriosus occlusion: application in the small child.
OBJECTIVE
This study intended to evaluate application of transcatheter occlusion of the patent ductus arteriosus in children < 10 kg body weight.


BACKGROUND
Transcatheter occlusion of the patent ductus arteriosus in the child weighing > 10 kg has been proved safe and effective.


METHODS
We reviewed 74 consecutive patients weighing < 10 kg (median 8.1 kg, range 3.98 to 10) and aged 4 to 30 months (median 13 months) who underwent patent ductus arteriosus occlusion between June 1986 and November 1992. A modification of the delivery system to facilitate application in small children is described.


RESULTS
A 12-mm device was implanted in 50 patients and a 17-mm device in 24. Three device embolizations occurred early in the experience, and one required removal because of hemolysis associated with a moderate residual shunt. One 17-mm device was removed at catheterization because of acute compromise to left pulmonary artery flow after implantation. Prevalence of residual shunting was 33% at 6 months, 20% at 12 to 18 months and 17% at 2-year follow-up and was not related to device, age, weight or size of the patent ductus. Altered flow to the left pulmonary artery was noted in seven patients (9.9%), with more significant compromise associated with the 17-mm device.


CONCLUSIONS
Transcatheter patent ductus arteriosus occlusion is feasible in the small child < 10 kg, particularly with the use of a modified delivery system. However, implantation of a 17-mm device in this patient population may impair flow to the left lung and should be reserved for the symptomatic child.
Nykanen
D G
DG
Department of Pediatrics, University of Toronto Faculty of Medicine, Ontario, Canada.
Hayes
A M
AM
Benson
L N
LN
Freedom
R M
RM
D006328:Cardiac Catheterization / Q000379:methods*; D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D011651:Pulmonary Artery / Q000503:physiopathology