Effects of contralateral acoustic stimulation on otoacoustic emissions following vestibular neurectomy.
This study demonstrates that, following unilateral vestibular neurectomy, the inhibitory effect of contralateral acoustic stimulation on evoked otoacoustic emissions is absent. The patient acts as her own control in that the unoperated side shows normal suppression of otoacoustic emission amplitude with contralateral acoustic stimulation. The lack of interaural suppression of otoacoustic emissions on the sectioned side, in the presence of normal acoustic reflex threshold levels, provides evidence that observed phenomena are not merely a function of middle ear reflex activity. It is concluded that the lack of inhibition in the operated ear is due to the sectioning of the olivocochlear bundle within the inferior vestibular nerve, removing the efferent control of the receptor cells. Otoacoustic emissions recorded during contralateral acoustic stimulation may thus provide a rapid, non-invasive means of investigating the functional of the efferent auditory system.
Williams
E A
EA
Department of Neuro-otology, National Hospital for Neurology and Neurosurgery, London, UK.
Brookes
G B
GB
Prasher
D K
DK
D000161:Acoustic Stimulation; D000328:Adult; D001300:Audiometry, Evoked Response; D001301:Audiometry, Pure-Tone; D003051:Cochlea / Q000502:physiology; D005260:Female; D006198:Hair Cells, Auditory / Q000502:physiology; D006309:Hearing; D006801:Humans; D009434:Neural Pathways / Q000502:physiology; D012022:Reflex, Acoustic / Q000502:physiology*; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology; D015837:Vestibular Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D014722:Vestibule, Labyrinth / Q000503:physiopathology / Q000601:surgery*