title: Chlamydial etiology of acute lower respiratory tract infections in children in the Sudan.
abstract: The role of Chlamydia pneumoniae in 110 Sudanese children with signs of acute lower respiratory tract infections (ALRI) was investigated. Four (3.6%) had evidence of C. pneumoniae infection, of whom 3 were culture-positive, while 1 had an antibody response suggesting a recent infection. IgG antibodies at a titer of > or = 1:32 to C. pneumoniae, Chlamydia psittaci and Chlamydia trachomatis were detected in 27 (24.5%), 27 (24.5%) and 7 (6.4%) of the 110 ALRI cases, respectively. C. pneumoniae, C. trachomatis or C. psittaci were not detected in nasopharyngeal secretions from any of 110 patients when fluorescence-labeled specific monoclonal antibodies were used. In a seroepidemiological survey, 318 healthy Sudanese persons aged between 1 month and 67 years were studied for C. pneumoniae antibodies.
authors.affiliation: Institute of Clinical Bacteriology, University of Uppsala, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Herrmann
authors.forename: M A
authors.initials: MA
authors.lastname: Salih
authors.forename: B E
authors.initials: BE
authors.lastname: Yousif
authors.forename: O
authors.initials: O
authors.lastname: Abdelwahab
authors.forename: P A
authors.initials: PA
authors.lastname: Mårdh
mesh_terms: D000208:Acute Disease; D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D002690:Chlamydia Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D016993:Chlamydophila pneumoniae / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D008297:Male; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology*; D016036:Seroepidemiologic Studies; D013397:Sudan / Q000453:epidemiology
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G