title: Human small intestinal contractions and aboral traction forces during fasting and after feeding.
abstract: Small intestinal intraluminal pressure activity and aboral traction forces were explored in 19 healthy volunteers using a combined manometry and traction force detecting assembly sited in the upper small intestine. Each aboral traction event was classified as being associated with either a propagating or a stationary contraction and its force measured. During phase I no contractions or traction events were seen. During phase II, traction events related to propagating contractions mean (SEM) (2.2 (0.2)/min) and to stationary contractions (0.3 (0.1)/min) generated similar force/event (7.5(0.9 g v 8.7 (1.4) g, p > 0.05). During phase III, all traction events were related to propagating contractions and generated 9.3 (2.4) g force/event (p > 0.05 v phase II). After feeding, traction events related to propagating contractions generated similar force/event to those related to stationary contractions (5.9 (1.0) g v 9.3 (2.7) g, p > 0.05 v each other and v fasting). No consistent pattern was seen in the temporal distribution of the traction events or in the pattern of the amplitude of the force of successive traction events.
authors.affiliation: Department of Medicine, University of Manchester Medical School, Hope Hospital.
authors.forename: N K
authors.initials: NK
authors.lastname: Ahluwalia
authors.forename: D G
authors.initials: DG
authors.lastname: Thompson
authors.forename: J
authors.initials: J
authors.lastname: Barlow
authors.forename: L
authors.initials: L
authors.lastname: Heggie
mesh_terms: D000328:Adult; D004435:Eating / Q000502:physiology*; D005215:Fasting / Q000502:physiology*; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D007421:Intestine, Small / Q000502:physiology*; D008297:Male; D008365:Manometry / Q000379:methods; D014160:Transducers, Pressure