[Lupus in children in Tunisia].
In this study, we have analyzed the clinical and serological features related to 16 Tunisian children in whom diagnosis of systemic lupus erythematosus was made before or at the age of 15. Renal involvement was found in 75% of cases and renal biopsies have mostly revealed severe histologic patterns. All of the patients who have been followed received corticosteroids and in some cases required additional cytotoxic drugs in order to control disease activity. Five children died in a context of a renal failure. This study of childhood lupus in Tunisia confirms that the clinical course of this disease in children is often aggressive.
Yalaoui
S
S
Laboratoire d'immunologie, faculté de médecine, Tunis, Tunisie.
Gorgi
Y
Y
Meddeb
S
S
Makni
S
S
Lakhoua
R
R
Debbabi
A
A
Ayed
K
K
Ben Maiz
H
H
Hamza
M
M
D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000453:epidemiology* / Q000276:immunology; D008181:Lupus Nephritis / Q000453:epidemiology / Q000209:etiology; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors
Lupus de l'enfant en Tunisie.