Differential electron capture mass spectral response of pentafluorobenzoyl derivatives of platelet activating factor alkyl chain homologs.
The electron capture mass spectrometric response of pentafluorobenzoyl ester derivatives of platelet-activating factor alkyl chain homologs has been found to be inversely proportional to their alkyl chain length. This phenomenon was observed when either the gas chromatograph or direct insertion probe was utilized for sample introduction. A similar differential response was also obtained for a series of fatty alcohols, analyzed as pentafluorobenzoyl esters. These studies demonstrate that multiple standard curves must be prepared for analysis of platelet-activating factor and related lipids in order to obtain accurate quantification.
Weintraub
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ST
Department of Pathology, University of Texas Health Science Center at San Antonio 78284-7750.
Lear
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C
Pinckard
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D001565:Benzoates / Q000737:chemistry*; D005233:Fatty Alcohols / Q000737:chemistry; D013058:Mass Spectrometry; D010972:Platelet Activating Factor / Q000737:chemistry*; D010738:Type C Phospholipases / Q000737:chemistry; D005464:Fluorobenzenes; D005466:Fluorocarbons
D001565:Benzoates; D005233:Fatty Alcohols; D010972:Platelet Activating Factor; D010738:Type C Phospholipases; C014737:pentafluorobenzoyl chloride; D005464:Fluorobenzenes; D005466:Fluorocarbons