title: Changes in serum C-reactive protein levels in dogs with various disorders and surgical traumas.
abstract: The serum levels of C-reactive protein (CRP) produced as an inflammatory response in dogs with various disorders and surgical traumas were measured by enzyme-linked immunoabsorbent assay and slide reversed passive latex agglutination test (RPLA). The CRP levels were greatly increased 1-2 days after surgery in most of the dogs (n = 29) subjected to surgery. These levels had markedly decreased by the time the sutures were removed. In dogs with various disorders (n = 58), the serum CRP levels at first diagnosis were high in infectious diseases. In dogs from which paired serum samples were examined, the serum CRP usually showed a decrease with improvement in the condition (n = 11) or a terminal increase (n = 4) but, conversely, some showed an increase with improvement in the condition (n = 3).
authors.affiliation: Department of Immunology, Faculty of Environmental Health, Azabu University, Kanagawa, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Shida
authors.forename: S
authors.initials: S
authors.lastname: Miyaji
authors.forename: H
authors.initials: H
authors.lastname: Santsuka
authors.forename: H
authors.initials: H
authors.lastname: Fujise
authors.forename: K
authors.initials: K
authors.lastname: Mukawa
authors.forename: E
authors.initials: E
authors.lastname: Furukawa
authors.forename: T
authors.initials: T
authors.lastname: Nagae
authors.forename: M
authors.initials: M
authors.lastname: Naiki
mesh_terms: D000818:Animals; D002097:C-Reactive Protein / Q000096:biosynthesis*; D004283:Dog Diseases / Q000097:blood* / Q000601:surgery; D004285:Dogs / Q000293:injuries / Q000601:surgery*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D007841:Latex Fixation Tests / Q000662:veterinary; D007958:Leukocyte Count; D011184:Postoperative Period; D013245:Sterilization, Reproductive / Q000662:veterinary; D014947:Wounds and Injuries / Q000097:blood / Q000662:veterinary
chemical_list: D002097:C-Reactive Protein