title: [Mitral valve prolapse. A possible cause of retinal vascular occlusion in young patients].
abstract: Retinal vessel occlusion in the elderly is considered to be of arteriosclerotic etiology, but in young patients the reasons for retinal vessel occlusions are manifold and much more obscure. We report on five patients under the age of 45 years who had retinal artery occlusion or retinal vein obstruction. A detailed general investigation revealed nothing but an identical cardiac abnormality in all five cases: mitral valve prolapse (MVP). A potential explanation for the coincidence of retinal vessel occlusion and MVP might be local hyperaggregability of platelets generated by the prolapsing mitral valve. In conclusion, to prevent retinal vessel occlusion from recurring in patients with proven MVP, medication containing platelet aggregation inhibitors should be given.
authors.affiliation: Universitäts-Augenklinik Düsseldorf.
authors.forename: M
authors.initials: M
authors.lastname: Schimkat
authors.forename: D
authors.initials: D
authors.lastname: Horstkotte
authors.forename: R
authors.initials: R
authors.lastname: Sundmacher
mesh_terms: D000328:Adult; D000368:Aged; D001241:Aspirin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000150:complications*; D015356:Retinal Artery Occlusion / Q000209:etiology* / Q000517:prevention & control
chemical_list: D001241:Aspirin
vernacular_title: Der Mitralklappenprolaps. Mögliche Ursache retinaler Gefässverschlüsse junger Menschen.