title: Disturbance of colour perception in Parkinson's disease.
abstract: A computer-aided method for the determination of colour fusion time (CFT) was developed. CFT indicates the acuity of the perception of monochromatic contours. CFT was determined in 36 patients with Parkinson's disease (PD) and compared with a group of 36 age- and sex-matched controls. Patients with PD generally had a shortened fusion time, especially for dark-green, light-blue and dark-red stimuli. The results give evidence to the hypothesis of a colour perception disorder in PD. The physiological and pathoanatomical basis of this phenomenon is unknown, but a functional deficit of cortical neurons may be a probable cause.
authors.affiliation: Department of Neurology, Ruhr-University Bochum, St. Josef-Hospital, Federal Republic of Germany.
authors.forename: T
authors.initials: T
authors.lastname: Büttner
authors.forename: W
authors.initials: W
authors.lastname: Kuhn
authors.forename: P
authors.initials: P
authors.lastname: Klotz
authors.forename: R
authors.initials: R
authors.lastname: Steinberg
authors.forename: L
authors.initials: L
authors.lastname: Voss
authors.forename: D
authors.initials: D
authors.lastname: Bulgaru
authors.forename: H
authors.initials: H
authors.lastname: Przuntek
mesh_terms: D000328:Adult; D000368:Aged; D003118:Color Perception / Q000502:physiology*; D003119:Color Perception Tests; D003201:Computers; D005260:Female; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy / Q000523:psychology*; D012642:Selegiline / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D012642:Selegiline; D007980:Levodopa