[Study by the immunofluorescence reaction of antibodies directed against antigens of the gut epithelium of Schistosoma mansoni. V. Modulation of granulomatous reaction around the egg under the influence of an IgM monoclonal antibody].
The periovular granulomatous reaction has been reduced in vivo by an IgM monoclonal antibody. The granulomatous reaction has been obtained either in unsensitized, or sensitized as well as immunized mouse. The granulomatous reduction could be explained by a decrease in egg viability, owing to the fact that the monoclonal antibody is lethal against an in vitro miracidium suspension.
Boisseau
H
H
Laboratoire d'Immunologie et Biologie Parasitaire, Faculté de Médecine Paul Broca, Université de Bordeaux II.
Ben Younes
R
R
Appriou
M
M
Tribouley-Duret
J
J
Tribouley
J
J
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D004848:Epithelium / Q000276:immunology / Q000469:parasitology; D005455:Fluorescent Antibody Technique; D006099:Granuloma / Q000276:immunology*; D007422:Intestines / Q000276:immunology* / Q000469:parasitology; D051379:Mice; D012550:Schistosoma mansoni / Q000276:immunology* / Q000502:physiology; D012555:Schistosomiasis mansoni / Q000276:immunology / Q000469:parasitology
D000911:Antibodies, Monoclonal
Etude par la réaction d'mmunofluorescence des anticorps dirigés contre les antigènes de l'épithélium intestinal de Schistosoma mansoni. V. Modulation de la réaction granulomateuse autour de l'oeuf sous l'influence d'un anticorps monoclonal de classe IgM.