[The effect of Amanita phalloides poison on the ultrastructure of neutrophilic granulocytes].
Changes of the ultrastructure of neutrophil granulocytes under the effect of Amanita phalloides was manifested by destabilization of cytoplasmic and organoid membranes, degranulation of the cytoplasm, appearance of areas of autolysis and lysed cells. The degree of destruction rose with increase of the dose and incubation time.
Kuz'menko
S A
SA
D000546:Amanitins / Q000633:toxicity*; D002478:Cells, Cultured / Q000187:drug effects / Q000648:ultrastructure; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007928:Lethal Dose 50; D008854:Microscopy, Electron; D009504:Neutrophils / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
D000546:Amanitins
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