title: [Splenic rupture in chronic pancreatitis. A clinical case. Observations].
abstract: The paper reports a case of splenic rupture during the course of chronic pancreatitis, an event rarely reported in the literature. The anatomical arrangement of organs and peripancreatic vessels is a predisposing factor for this complication. There are essentially three different but correlated pathogenetic hypotheses. The first refers to thrombosis of the splenic vein with portal hypertension documented by some researchers even in angiographical terms: during the course of chronic pancreatitis the spleen is sometimes palpable. Thrombosis and/or vascular compression make the spleen more fragile and its rupture more likely: this is particularly true during the course of calcific chronic pancreatitis and cases involving the tail. An enzymatic factor may also be responsible and this appears more clearly in pancreatitis with pseudocysts. In this case it is the direct action of pancreatic enzymes on the ileum or splenic parenchyma, which may also affect all organs surrounding the pancreas, which leads to hemorrhage or hematoma. Sometimes the cause of bleeding is a pseudoaneurysm of the splenic artery which is eroded by the contents of the pseudocysts themselves. There is also a mechanical hypothesis which some authors consider the sole possibility: in chronic pancreatitis the splenic compartment presents severe perisplenitis which fixes the spleen making it more vulnerable and even a mini-trauma will cause rupture. The patient is almost always an emaciated young alcoholic suffering from chronic pancreatic pathology.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Divisione di Chirurgia Generale, Ospedale Civile, La Spezia.
authors.forename: M
authors.initials: M
authors.lastname: Nincheri Kunz
authors.forename: L
authors.initials: L
authors.lastname: Evaristi
authors.forename: M
authors.initials: M
authors.lastname: Pera
authors.forename: A
authors.initials: A
authors.lastname: Veneroso
authors.forename: R
authors.initials: R
authors.lastname: Cozzani
authors.forename: L
authors.initials: L
authors.lastname: Caliendo
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012422:Rupture, Spontaneous; D013154:Spleen / Q000473:pathology; D013156:Splenectomy; D013161:Splenic Rupture / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000601:surgery
vernacular_title: Rottura di milza in corso di pancreatite cronica. Caso clinico. Considerazioni.