Epileptogenic potential of antimalarial drugs.
Available clinical reports suggest that antimalarial drugs may cause epileptic seizures as an adverse reaction in susceptible individuals. Epileptic patients and others with a low seizure threshold appear particularly prone. Antimalarial drugs, particularly chloroquine and mefloquine, should be used with caution by patients with epilepsy.
Adamolekun
B
B
Department of Medicine, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
D000328:Adult; D015984:Causality; D002738:Chloroquine / Q000009:adverse effects*; D003906:Developing Countries; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D015767:Mefloquine / Q000009:adverse effects; D011796:Quinacrine / Q000009:adverse effects
D002738:Chloroquine; D011796:Quinacrine; D015767:Mefloquine