[The activity of the antioxidant system and membrane lipid peroxidation in hypertension patients].
With the view to study state of antioxidant protection and membrane lipid peroxidation (LPO) in hypertonic disease (HD) 200 patients with HD of I and II stage (WHO classification) were examined. Structural and functional state of myocardium was assessed echocardiographically. Enzymatic and non-enzymatic LPO, catalase and superoxide-dismutase activity were analyzed in erythrocytes. Destabilization of cell membranes due to LPO activation and alteration of antioxidant potential established in patients with HD was paralleled by the degree of left ventricle hypertrophy.
Polivoda
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Shershnev
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VG
D000975:Antioxidants; D002374:Catalase / Q000097:blood; D002463:Cell Membrane Permeability; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D017379:Hypertrophy, Left Ventricular / Q000097:blood; D015227:Lipid Peroxidation; D008297:Male; D008563:Membrane Lipids / Q000097:blood*; D008875:Middle Aged; D013482:Superoxide Dismutase / Q000097:blood
D000975:Antioxidants; D008563:Membrane Lipids; D002374:Catalase; D013482:Superoxide Dismutase
Aktivnost' antioksidantnykh sistem i sostoianie perekisnogo okisleniia lipidov membran u bol'nykh gipertonicheskoĭ bolezn'iu.