[The effect of prolonged exposure to UV radiation on the state of the ocular media and on the parameters of the electroretinogram in the rabbit].
Rabbits were exposed to vertically directed UV-B radiation (280-320 nm) 5 days a week during 10 months with daily dose 6.5 J/m2 (biological effective daily dose 0.83 J/m2). Within the first week expressed photokeratoconjunctivitis was observed, but to the end of third week state of cornea and conjunctiva became practically normal. Transparency of intra-eye structures was unchanged, functional activity of retina underwent undulatory alterations. Amplitude changes of a- and b-waves of electroretinogram reached 30% of control values during the first, were negligible within the second, and exceed control by 15-20% between 8 and 10-th months of exposure. Critical frequency of flashing was unchanged.
Belousov
V M
VM
Zaugol'nikova
L A
LA
Kniazev
V M
VM
Strzhizhovskiĭ
A D
AD
D000222:Adaptation, Physiological / Q000528:radiation effects; D000818:Animals; D004596:Electroretinography / Q000528:radiation effects*; D005123:Eye / Q000503:physiopathology / Q000528:radiation effects*; D005425:Flicker Fusion / Q000528:radiation effects; D007637:Keratoconjunctivitis / Q000209:etiology / Q000503:physiopathology; D011817:Rabbits; D011833:Radiation Injuries, Experimental / Q000209:etiology / Q000503:physiopathology; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects*
Vliianie dlitel'nogo vozdeĭstviia UF-izlucheniia na sostoianie glaznykh sred i parametry élektroretinogrammy krolika.