title: Risk factors for HIV-1 and HIV-2 infection in pregnant women in Dakar, Senegal.
abstract: This study examines the prevalence and risk factors for Human Immunodeficiency Virus type 1 (HIV-1) and type 2 (HIV-2) infection in pregnant women in Dakar, Senegal. From April 1991 to January 1993, 9,518 pregnant women were interviewed and serologically tested for antibodies to HIV-1 and HIV-2; 26 (0.3%) were HIV-1 seropositive, 44 (0.5%) were HIV-2 seropositive, two (0.02%) were dually seropositive, and 9,448 (99.3%) were seronegative. Guinea-Bissau nationality and age > 25 years were associated with HIV-2 infection, whereas parity < or = 2 was associated with HIV-1 infection. Among women who gave birth to live infants, shorter length of union with the partner and having been married more than once were associated with HIV-2 infection, whereas age < or = 25 years was associated with HIV-1 infection. Information gained by this study may help target intervention strategies for preventing maternal HIV infection and understanding biological differences between the two viruses.
authors.affiliation: Department of Cancer Biology, Harvard School of Public Health, Boston, Massachusetts 02115.
authors.forename: R C
authors.initials: RC
authors.lastname: Abbott
authors.forename: A
authors.initials: A
authors.lastname: NDour-Sarr
authors.forename: A
authors.initials: A
authors.lastname: Diouf
authors.forename: T
authors.initials: T
authors.lastname: NDoye
authors.forename: D
authors.initials: D
authors.lastname: Bâ
authors.forename: N
authors.initials: N
authors.lastname: Tall
authors.forename: N
authors.initials: N
authors.lastname: MBaye
authors.forename: F
authors.initials: F
authors.lastname: Kébé
authors.forename: F
authors.initials: F
authors.lastname: Diadhiou
authors.forename: M E
authors.initials: ME
authors.lastname: Essex
mesh_terms: D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D005260:Female; D006169:Guinea-Bissau / Q000208:ethnology; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1 / Q000276:immunology; D015498:HIV-2 / Q000276:immunology; D006801:Humans; D015999:Multivariate Analysis; D010298:Parity; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012675:Senegal / Q000453:epidemiology; D012747:Sexual Partners; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
chemical_list: D015483:HIV Antibodies