title: [Effect of cholelithiasis and cholecystectomy on duodenogastric biliary reflux].
abstract: The aim of this work was to study the influence of cholelithiasis and cholecystectomy on duodenogastric biliary reflux. Total bile acid concentration (TBAC) in fasting gastric juice was measured in 23 consecutive patients with cholelithiasis and functioning gallbladder before and at least 3 months after cholecystectomy (group 1) and in 14 healthy volunteers (group II). In group two, TBAC was 8.5 +/- 2.8 uMol/l (mean +/- sem), the preoperative value in group I was 32.8 +/- 8.9 uMol/l and the postoperative value 69.9 +/- 14 uMol/l (p < 0.002 compared with group II and < 0.035 compared with preoperative values). These results suggest that cholelithiasis, even with a functioning gallbladder is associated with a significant increase in bile reflux to the stomach, with raises further after cholecystectomy.
authors.affiliation: Departamento de Cirugía, Facultad de Medicina, Universidad de Concepción, Chile.
authors.forename: M
authors.initials: M
authors.lastname: Anselmi
authors.forename: C
authors.initials: C
authors.lastname: Milos
authors.forename: H
authors.initials: H
authors.lastname: Schultz
authors.forename: M A
authors.initials: MA
authors.lastname: Muñoz
authors.forename: R
authors.initials: R
authors.lastname: Alvarez
authors.forename: J
authors.initials: J
authors.lastname: Maturana
mesh_terms: D000328:Adult; D000368:Aged; D001647:Bile Acids and Salts / Q000032:analysis; D002763:Cholecystectomy; D002769:Cholelithiasis / Q000503:physiopathology* / Q000601:surgery; D004383:Duodenogastric Reflux / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013270:Stomach / Q000737:chemistry
chemical_list: D001647:Bile Acids and Salts
vernacular_title: Efecto de la colelitiasis y de la colecistectomia sobre el reflujo duodenogastrico de bilis.