title: Staging of prostate cancer: results of Radiology Diagnostic Oncology Group project comparison of three MR imaging techniques.
abstract: OBJECTIVE
  To assess accuracy of three different magnetic resonance (MR) imaging techniques, including the endorectal coil, in staging prostate cancer.
  
  
  METHODS
  MR imaging was performed in 213 patients with prostate cancer with a conventional body coil, with fat suppression and a body coil, and with an endorectal coil. Radiologists identified tumor invasion into periprostatic tissues, neurovascular bundles, and seminal vesicles. Each technique was evaluated separately, and in a subset of 74 patients the three techniques were evaluated together. Images obtained with the two body-coil techniques were read in combination with images obtained with the endorectal coil (combination A) and alone (combination B).
  
  
  RESULTS
  Overall accuracy for conventional body-coil, fat-suppressed body-coil, and endorectal-coil MR was 61%, 64%, and 54%, respectively. Overall group accuracy for combinations A and B was 57% and 61%. Considerable interreader variability was found for combination A.
  
  
  CONCLUSIONS
  No technique was highly accurate for staging early prostate cancer. Individual radiologists did achieve a high degree of staging accuracy with the endorectal-coil and body-coil combination.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, Md.
authors.forename: C M
authors.initials: CM
authors.lastname: Tempany
authors.forename: X
authors.initials: X
authors.lastname: Zhou
authors.forename: E A
authors.initials: EA
authors.lastname: Zerhouni
authors.forename: M D
authors.initials: MD
authors.lastname: Rifkin
authors.forename: L E
authors.initials: LE
authors.lastname: Quint
authors.forename: C W
authors.initials: CW
authors.lastname: Piccoli
authors.forename: J H
authors.initials: JH
authors.lastname: Ellis
authors.forename: B J
authors.initials: BJ
authors.lastname: McNeil
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012372:ROC Curve; D012680:Sensitivity and Specificity