title: The microcirculation in venous disease.
abstract: The author discusses three factors involved in venous ulceration: skin hypoxia, white-cell trapping, abnormalities in regulation of the microcirculation, eg, neuropathy. Leukocytes remain the most likely initiating factor.
authors.affiliation: Department of Surgery, Middlesex Hospital, London, England.
authors.forename: J H
authors.initials: JH
authors.lastname: Scurr
authors.forename: P D
authors.initials: PD
authors.lastname: Coleridge-Smith
mesh_terms: D006801:Humans; D007866:Leg / Q000098:blood supply; D007962:Leukocytes / Q000502:physiology; D008833:Microcirculation; D010100:Oxygen / Q000097:blood; D012867:Skin / Q000098:blood supply*; D014647:Varicose Ulcer / Q000097:blood / Q000503:physiopathology*
chemical_list: D010100:Oxygen