1,3-Diarylindan-2-carboxylic acids, potent and selective non-peptide endothelin receptor antagonists.
Elliott
J D
JD
Research and Development Division, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406-0939.
Lago
M A
MA
Cousins
R D
RD
Gao
A
A
Leber
J D
JD
Erhard
K F
KF
Nambi
P
P
Elshourbagy
N A
NA
Kumar
C
C
Lee
J A
JA
D000595:Amino Acid Sequence; D000818:Animals; D065128:Endothelin Receptor Antagonists; D016232:Endothelins / Q000737:chemistry / Q000502:physiology; D007189:Indans / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D051381:Rats; D017466:Receptors, Endothelin / Q000378:metabolism
D065128:Endothelin Receptor Antagonists; D016232:Endothelins; D007189:Indans; D017466:Receptors, Endothelin; C087551:1H-Indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1S,2R,3S)-