title: Using pyridoxine to treat carpal tunnel syndrome. Randomized control trial.
abstract: In this study, we examined prospectively the effect of pyridoxine on idiopathic carpal tunnel syndrome. Thirty-two patients with the disease were randomized to receive treatment or placebo. No differences in outcome were found in electrophysiologic signs, clinical signs, or significant symptoms. Our findings do not support the use of pyridoxine for treating carpal tunnel syndrome.
authors.affiliation: Department of Family Medicine, University of Alberta, Edmonton.
authors.forename: G R
authors.initials: GR
authors.lastname: Spooner
authors.forename: H B
authors.initials: HB
authors.lastname: Desai
authors.forename: J F
authors.initials: JF
authors.lastname: Angel
authors.forename: B A
authors.initials: BA
authors.lastname: Reeder
authors.forename: J R
authors.initials: JR
authors.lastname: Donat
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001219:Aspartate Aminotransferases / Q000097:blood; D002349:Carpal Tunnel Syndrome / Q000188:drug therapy* / Q000503:physiopathology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology; D010349:Patient Compliance; D010919:Placebos; D011732:Pyridoxal Phosphate / Q000097:blood; D011736:Pyridoxine / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D011930:Reaction Time / Q000502:physiology
chemical_list: D010919:Placebos; D011732:Pyridoxal Phosphate; D001219:Aspartate Aminotransferases; D011736:Pyridoxine