title: Brainstem auditory evoked response changes following electro-acupuncture therapy in chronic pain patients.
abstract: Brainstem auditory evoked responses were recorded in 17 patients with chronic pain who had been given electro-acupuncture therapy. The absolute peak latencies of waves I to V, and interpeak latencies and amplitudes of waves I and V were analysed before electro-acupuncture and compared with values obtained during electro-acupuncture and 5 min after its termination after one, five and 10 sittings. At these sittings the intensity of pain was recorded with the help of a 100 mm visual analogue scale. Each patient had 10 sittings given on alternate days. The absolute peak latencies of waves I, II, and III were delayed significantly (p < 0.05) after 5 and 10 sittings and amplitudes of wave V decreased significantly (p < 0.05) after 5 and 10 sittings. Visual analogue scores also decreased significantly (p < 0.01) during these sittings. It was established that before and after 10 sittings of electro-acupuncture, there was a significant positive correlation between visual analogue scores and the amplitude of wave V (p < 0.01). There was a negative correlation between visual analogue scores and absolute peak latencies of wave III at 1, 5 and 10 sittings, suggesting that there is a definite interaction between the electro-acupuncture neural mechanism and the generators of brainstem auditory evoked responses in the lower brainstem.
authors.affiliation: Department of Anaesthesiology and Critical Care, University College of Medical Sciences, Delhi, India.
authors.forename: A
authors.initials: A
authors.lastname: Kumar
authors.forename: O P
authors.initials: OP
authors.lastname: Tandon
authors.forename: S
authors.initials: S
authors.lastname: Dam
authors.forename: A
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: K K
authors.initials: KK
authors.lastname: Tyagi
mesh_terms: D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D015671:Electroacupuncture; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000503:physiopathology*; D059408:Pain Management; D010147:Pain Measurement; D011930:Reaction Time