title: Hypothalamic, striatal and plasma leucine enkephalin level in two rat models of portal hypertension.
abstract: In two rat models of portal hypertension obtained by common bile duct obstruction or by partial portal vein ligation the hypothalamic level of leu-enkephalin was increased but striatal and plasma level of leu-enkephalin was unchanged. These results may be of importance for understanding some disturbance related to hepatic encephalopathy.
authors.affiliation: Department of Clinical Pharmacology, Medical Academy, Katowice, Poland.
authors.forename: M J
authors.initials: MJ
authors.lastname: Klin
authors.forename: M
authors.initials: M
authors.lastname: Waluga
authors.forename: A
authors.initials: A
authors.lastname: Madej
authors.forename: A
authors.initials: A
authors.lastname: Plewka
authors.forename: Z S
authors.initials: ZS
authors.lastname: Herman
mesh_terms: D000818:Animals; D001663:Bilirubin / Q000097:blood; D003342:Corpus Striatum / Q000378:metabolism*; D004195:Disease Models, Animal; D004743:Enkephalin, Leucine / Q000032:analysis / Q000378:metabolism*; D006975:Hypertension, Portal / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism*; D008099:Liver / Q000473:pathology; D008297:Male; D009929:Organ Size; D011863:Radioimmunoassay; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000473:pathology
chemical_list: D004743:Enkephalin, Leucine; D001663:Bilirubin