title: [An analysis of chromosome aberrations and SCE in children from radiation-contaminated regions of Ukraine].
abstract: About a two years later after the reactor accident in Chernobyl we carried out a three-year cytogenetical study of children, dwelling in two regions of Ukraine where the radiation fallout occurred. Chromosome analyses of these individuals have shown a significant increase of the frequency of aberrant cells and chromosomal type aberrations in comparison to the control. We have discovered the increase of the level of chromosomal type aberrations, extension in spectrum of complicate aberrations of chromosome (dicentrics, rings and exchange aberrations) with the years and the increase with the years a share of children with various chromosomal abnormalities. Analyses of sister chromatid exchanges (SCE) and a replication index (RI) show a significant increase of RI meaning with the years in comparison to the control. The SCE frequency didn't altered as compared to the control during different years of investigation.
authors.forename: I M
authors.initials: IM
authors.lastname: Eliseeva
authors.forename: E L
authors.initials: EL
authors.lastname: Iofa
authors.forename: E F
authors.initials: EF
authors.lastname: Stoian
authors.forename: V A
authors.initials: VA
authors.lastname: Shevchenko
mesh_terms: D000062:Accidents, Occupational; D000398:Air Pollution, Radioactive / Q000009:adverse effects*; D002648:Child; D002869:Chromosome Aberrations; D006801:Humans; D008677:Metaphase / Q000528:radiation effects; D009031:Moscow; D009688:Nuclear Reactors; D011210:Power Plants; D012424:Rural Population; D012854:Sister Chromatid Exchange / Q000528:radiation effects*; D013997:Time Factors; D014455:Ukraine; D014505:Urban Population
vernacular_title: Analiz aberratsiĭ khromosom i SKhO u deteĭ iz radiatsionno-zagriaznennykh raĭonov Ukrainy.