title: An algorithm combining DNA and protein alignment.
abstract: An algorithm is presented that aligns two DNA sequences minimizing the overall amount of evolution that the associated proteins have experienced. It is generalized to minimizing a weighted average of protein and DNA evolution.
authors.affiliation: Institute of Biological Sciences, Aarhus University, Denmark.
authors.forename: J
authors.initials: J
authors.lastname: Hein
mesh_terms: D000465:Algorithms; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D004247:DNA / Q000235:genetics*; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics*; D016415:Sequence Alignment
chemical_list: D011506:Proteins; D004247:DNA