title: Epi-sarsasapogenin and epi-smilagenin: two sapogenins isolated from the rumen content of sheep intoxicated by Brachiaria decumbens.
abstract: Spectroscopic examination of purified extracts of the rumen content of sheep intoxicated by Brachiaria decumbens revealed the presence of two spirostanes, identified as epi-sarsasapogenin and epi-smilagenin. Sarsasapogenone was obtained by the oxidation of sarsasapogenin. The reduction of sarsasapogenone using lithium aluminum hydride yielded isomeric products, sarsasapogenin (20%) and epi-sarsasapogenin (80%).
authors.affiliation: Department of Chemistry, Universiti Pertanian Malaysia, Selangor D. E.
authors.forename: N H
authors.initials: NH
authors.lastname: Lajis
authors.forename: A S
authors.initials: AS
authors.lastname: Abdullah
authors.forename: S J
authors.initials: SJ
authors.lastname: Salim
authors.forename: J B
authors.initials: JB
authors.lastname: Bremner
authors.forename: M N
authors.initials: MN
authors.lastname: Khan
mesh_terms: D000818:Animals; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D006109:Poaceae; D012417:Rumen / Q000737:chemistry* / Q000378:metabolism; D012502:Sapogenins / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D012756:Sheep; D012757:Sheep Diseases / Q000139:chemically induced*; D013150:Spirostans / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D012502:Sapogenins; D013150:Spirostans; C046296:sarsasapogenone; C046297:sarsasapogenin