[The interrelationship of the arterial and venous sections of the systemic vascular bed under the action of verapamil and propranolol].
Electromagnetic flowmetry and analogue computer techniques were used in the experiments on 12 anesthesized cats which indicated that verapamil increased cardiac output (CO) (due to lower afterload) and venous return (VR), distributed CO, by improving brain blood supply. The latter was due to more marked decrease in the vascular resistance of the brachiocephalic artery than that in the descending thoracic aorta. Propranolol diminished CO due to higher afterload, lower VR and cardiac pump function. At the same time blood flow in the brachiocephalic artery decreased to a lesser extent than that in the descending thoracic aorta. The blood flow changes in the great arteries, which were induced by the drug determined its use in the vena cava.
Kostko
S Z
SZ
D000818:Animals; D001158:Arteries / Q000187:drug effects* / Q000502:physiology; D001783:Blood Flow Velocity / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D003202:Computers, Analog; D055590:Electromagnetic Phenomena; D006339:Heart Rate / Q000187:drug effects; D011433:Propranolol / Q000494:pharmacology*; D012212:Rheology / Q000379:methods; D014655:Vascular Resistance / Q000187:drug effects; D014680:Veins / Q000187:drug effects* / Q000502:physiology; D014700:Verapamil / Q000494:pharmacology*
D011433:Propranolol; D014700:Verapamil
Vzaimootnoshenie arterial'nogo i venoznogo otdelov sistemnogo sosudistogo rusla pri deĭstvii verapamila i propranolola.