title: [Cerebral hemometabolism: from isolated measurements to monitoring and therapy].
abstract: An overview is presented on historical and multivariate aspects of cerebral hemometabolism. This involves a full multivariate approach, from blood pressure to cerebral metabolism. From isolated measurements, to monitoring and management, a comprehensive overview of cerebral hemometabolism is addressed, from its inception to current days, up to a new concept, the cerebral hemodynamic reserve. A multivariate functional diagram is proposed, to summarize the multivariate interrelationships of cerebral hemometabolism. A generic proposition is made for studies of truly normal cerebral hemometabolism in children, for subsequent clinical applications. Another proposition is made for multivariate cerebral hemometabolic monitoring, in a broad variety of circumstances of predominantly global changes in intracranial dynamics, both in animal and clinical research.
authors.affiliation: Division of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia 19104.
authors.forename: J
authors.initials: J
authors.lastname: Cruz
mesh_terms: D000328:Adult; D000818:Animals; D001921:Brain / Q000378:metabolism*; D001930:Brain Injuries / Q000378:metabolism / Q000628:therapy*; D002560:Cerebrovascular Circulation; D002648:Child; D006439:Hemodynamics; D006801:Humans; D007427:Intracranial Pressure; D007601:Jugular Veins; D008991:Monitoring, Physiologic / Q000379:methods; D010101:Oxygen Consumption
vernacular_title: Hemometabolismo cerebral. De medidas isoladas a medidas de monitorização e terapêutica.