title: [Neurophthalmological alterations in multiple sclerosis].
abstract: With the aim of defining the neuro-ophthalmological alterations in multiple sclerosis, both with respect to visual and oculomotor aspects, we have studied a sample of 100 clinically definite multiple sclerosis patients, all in the remittent phase of the disease. We compared them with a sample of 100 unrelated healthy controls, matched for age and sex. Visuomotor alterations were found in 99%, purely visual alterations in 38%, purely oculomotor alterations in 3%, and mixed alterations in 58% of the MS patients. Comparisons with controls showed significant statistical differences in all the tests used in the study. The neuro-ophthalmological examination in multiple sclerosis permits us to detect subclinical lesions and arrive at a better comprehension of central nervous system involvement in this disease, thereby contributing collaborating to better patient care.
authors.affiliation: Departamento de Medicina Interna, Hospital Regional de Málaga.
authors.forename: A
authors.initials: A
authors.lastname: Alcalá
authors.forename: O
authors.initials: O
authors.lastname: Fernández
authors.forename: C
authors.initials: C
authors.lastname: Juárez
mesh_terms: D017668:Age of Onset; D005260:Female; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D009886:Ophthalmoplegia / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D011681:Pupil Disorders / Q000503:physiopathology; D012029:Refraction, Ocular; D012160:Retina / Q000473:pathology* / Q000503:physiopathology
vernacular_title: Alteraciones neuroftalmológicas en la esclerosis múltiple.