title: [The morphofunctional indices of the erythrocytic link in hemopoiesis in persons constantly working in an area of intensified radioecological control].
abstract: A study of the peripheral blood indicates that persons constantly working in the zone of rigid radiation control showed a statistically valid reduction of the hemoglobin concentration, appearance of spinous and spheric erythrocyte forms, reduction of the mechanical resistance. Simultaneously 18% of males and 26% of females revealed moderate hypochromic anemia with a normal level of serum iron. The intensity of Fe-transferrin electron paramagnetic resonance was statistically reduced, that may be related to reduction of trivalent iron to bivalent and formation of a pool of free bivalent iron--a potent inductor of lipid peroxidation. Activation of oxidative processes in blood is confirmed by significant fluctuations of the blood ceruloplasmin level.
authors.forename: V I
authors.initials: VI
authors.lastname: Klimenko
authors.forename: L N
authors.initials: LN
authors.lastname: Iukhimuk
mesh_terms: D002570:Ceruloplasmin / Q000032:analysis / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004578:Electron Spin Resonance Spectroscopy; D004784:Environmental Monitoring; D004912:Erythrocytes / Q000166:cytology / Q000528:radiation effects*; D004920:Erythropoiesis / Q000528:radiation effects*; D005260:Female; D006801:Humans; D008297:Male; D008706:Methemoglobin / Q000032:analysis / Q000528:radiation effects; D016273:Occupational Exposure / Q000009:adverse effects*; D014168:Transferrin / Q000032:analysis / Q000528:radiation effects; D014455:Ukraine
chemical_list: D014168:Transferrin; D008706:Methemoglobin; D002570:Ceruloplasmin
vernacular_title: Morfofunktsional'nye pokazateli éritrotsitarnogo zvena gemopoéza u lits, postoianno rabotaiushchikh v zone usilennogo radioékologicheskogo kontrolia.