Considerations on HAM/TSP. Rediscovering Tumaco.
Considerations are made on the role of HTLV-I in the etiopathogeny of HAM/TSP. Neuroepidemiologic data reported in the literature are revisited for this purpose. Among results of this evaluation it is pointed-out that the Okinawan Community of Brazil presents ethnographic and demographic characteristics which are ideal for designing new studies. For instance, analyses on HTLV-I and on HAM/TSP in face of the cohort of such community classified according to time and direction of the migration (Japan-Brazil and vice-versa), will ensure promising results for the understanding of etipathogeny of HAM/TSP. They can also be paths towards clarifying the simultaneous generating, of geographical foci of the disease distant one the other, as that of Tumaco and that of south Japan.
Yasuda
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Department of Neurology, Faculty of Medicine, Unviersity of São Paulo, Brasil.
D016000:Cluster Analysis; D003105:Colombia / Q000453:epidemiology; D004641:Emigration and Immigration; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D015493:Paraparesis, Tropical Spastic / Q000453:epidemiology* / Q000209:etiology; D015995:Prevalence