title: Optic disk appearance in ocular hypertensive eyes.
abstract: We examined the optic disk appearance in ocular hypertensive eyes that had a normal result of conventional computed perimetry. Color stereo-optic disk photographs of 104 ocular hypertensive subjects and of 216 normal individuals were morphometrically evaluated. In the ocular hypertensive eyes as compared to the normal eyes, significant differences (P < .0001) were detected for a smaller area and an abnormal shape of the neuroretinal rim, larger zones alpha and beta of the parapapillary chorioretinal atrophy, a decreased visibility of the retinal nerve fiber layer, and a higher frequency of localized nerve fiber layer defects. The variables most useful to indicate optic nerve damage were an abnormal shape of the neuroretinal rim and a decreased visibility of the nerve fiber layer. The most specific variable was the presence of localized retinal nerve fiber layer defects. Evaluation of these variables may be helpful for the early diagnosis of glaucoma.
authors.affiliation: Department of Ophthalmology, University Eye Hospital, Erlangen, Germany.
authors.forename: J B
authors.initials: JB
authors.lastname: Jonas
authors.forename: K A
authors.initials: KA
authors.lastname: Königsreuther
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology; D009798:Ocular Hypertension / Q000473:pathology* / Q000503:physiopathology; D009898:Optic Disk / Q000473:pathology* / Q000503:physiopathology; D009900:Optic Nerve / Q000473:pathology; D012160:Retina / Q000473:pathology; D058609:Visual Field Tests