title: [Chronic urticaria-macroglobulinemia (Schnitzler syndrome): developing to IgM myeloma. Apropos of a case].
abstract: Schnitzler's syndrome has been described in 1972. It associates a chronic urticaria with leukocytoclastic vasculitis, a macroglobulinemia, bone pains, hyperostosis. In the twenty three cases reported, the evolution is benign but three patients including the princeps case developed a Waldenström's disease or a lymphoplasmocytic lymphoma. We present the case of one patient, aged 65, with Schnitzler's syndrome, who, after 6 years evolution, presents a IgM myeloma. Schnitzler's syndrome appeared as a pre-hemopathic state which has to be taken care of regularly and for a long time.
authors.affiliation: Service de rhumatologie, CHU, hôpital Sébastopol, Reims, France.
authors.forename: S
authors.initials: S
authors.lastname: Govindaraju
authors.forename: P
authors.initials: P
authors.lastname: Brochot
authors.forename: A C
authors.initials: AC
authors.lastname: Ringot
authors.forename: L
authors.initials: L
authors.lastname: Paternotte
authors.forename: A
authors.initials: A
authors.lastname: Morrone
authors.forename: J P
authors.initials: JP
authors.lastname: Eschard
authors.forename: J C
authors.initials: JC
authors.lastname: Etienne
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D002699:Chlorambucil / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D007075:Immunoglobulin M; D008297:Male; D009101:Multiple Myeloma / Q000188:drug therapy / Q000209:etiology*; D013577:Syndrome; D013997:Time Factors; D014581:Urticaria / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D000305:Adrenal Cortex Hormones; D007075:Immunoglobulin M; D002699:Chlorambucil
vernacular_title: Urticaire chronique-macroglobulinémie (syndrome de Schnitzler): évolution vers un myélome à IgM. A propos d'un cas.