title: Risk of melanoma after treatment of pigmented lesions with Solcoderm.
abstract: A 40-year-old patient developed a 5-mm-deep melanoma from a lesion on her chest which had been treated with Solcoderm 10 years previously. We recently described 3 other cases of melanoma that evolved in a lesion treated by Solcoderm. Much debate surrounds the recommendation as to the appropriate method for treatment of pigmented lesions when the removal is indicated for cosmetic reasons only. Most of the authors agree that any pigmented lesion which merits excision merits submission for histological examination. The aim of the present report was to express a warning regarding what we think is an inappropriate and hazardous method of treating pigmented lesions, namely their chemical destruction with Solcoderm. In view of the reported cases of melanoma evolving in lesions treated previously with Solcoderm, we believe that this treatment is absolutely contraindicated for pigmented lesions.
authors.affiliation: Department of Dermatology, Tel-Aviv Sourasky Medical Center, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Brenner
authors.forename: R
authors.initials: R
authors.lastname: Wolf
mesh_terms: D000085:Acetates / Q000009:adverse effects; D019342:Acetic Acid; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D003300:Copper / Q000009:adverse effects; D003879:Dermatologic Agents / Q000009:adverse effects; D005260:Female; D006801:Humans; D007773:Lactates / Q000009:adverse effects; D008545:Melanoma / Q000139:chemically induced*; D016609:Neoplasms, Second Primary / Q000139:chemically induced*; D009508:Nevus, Pigmented / Q000188:drug therapy*; D009566:Nitrates / Q000009:adverse effects; D012307:Risk Factors; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000188:drug therapy*
chemical_list: D000085:Acetates; D003879:Dermatologic Agents; D007773:Lactates; D009566:Nitrates; D003300:Copper; D019342:Acetic Acid