title: Do local hospitals meet the analytical goals for the use of common reference intervals?
abstract: Blood samples were obtained from 183 blood donors and measured in two hospitals in the same geographical area using identical reference intervals and measuring equipment. The analytical bias of the clinical chemical analyses was investigated through paired measurements. The results showed that out of 15 routine analyses only four meet the goals for acceptance of common reference intervals, of which at least three were of clinical significance. The problems were reflected in the quality assessment results but, nevertheless, no action seems to have been taken.
authors.affiliation: Department of Clinical Chemistry, KAS Herlev, University of Copenhagen, Denmark.
authors.forename: A
authors.initials: A
authors.lastname: Frølich
authors.forename: B F
authors.initials: BF
authors.lastname: Nielsen
authors.forename: J
authors.initials: J
authors.lastname: Nielsen
authors.forename: K
authors.initials: K
authors.lastname: Conradsen
authors.forename: P
authors.initials: P
authors.lastname: McNair
mesh_terms: D000328:Adult; D001774:Blood Chemical Analysis / Q000592:standards*; D003718:Denmark; D005260:Female; D006801:Humans; D007755:Laboratories, Hospital / Q000592:standards*; D008297:Male; D008875:Middle Aged; D011786:Quality Control; D012016:Reference Values