[Cytofluorimetric research on the epithelium of the cervix uteri in malignancy].
The cervical dysplasia and cancer of the uterine cervix of 82 patients have been studied by the cyto-fluorimetric technique. There were 46 patients with dysplasia of mild, moderate and severe degree and 36 patients with different histopathologic type cancer of the uterine cervix T1-2N0M0. DNA content was determined in cytological smears and scrapings of cervix uterus epithelium using luminescent microscope equipped with photometric device FMEI-1. The mean DNA content under dysplasia of cervix uterus reliably differed from that in control (3.504 +/- 0.054 and 4.715 +/- 0.051, respectively). The level of DNA content was heterogenic and elevated in cases of intraepithelial cancer and carcinoma in situ (8.369 +/- 0.84 and 10.098 +/- 0.28, respectively). This value was considerably higher than tumor progression (9,423 +/- 0.051).
Ganina
K P
KP
Nosa
P P
PP
Boroda
A N
AN
Klevetenko
M P
MP
D000293:Adolescent; D000328:Adult; D002277:Carcinoma / Q000737:chemistry; D002278:Carcinoma in Situ / Q000737:chemistry; D002467:Cell Nucleus / Q000737:chemistry; D002584:Cervix Uteri / Q000737:chemistry*; D004273:DNA, Neoplasm / Q000032:analysis; D004848:Epithelium / Q000737:chemistry; D005260:Female; D005434:Flow Cytometry / Q000295:instrumentation / Q000379:methods; D006801:Humans; D008875:Middle Aged; D002578:Uterine Cervical Dysplasia / Q000737:chemistry; D002583:Uterine Cervical Neoplasms / Q000737:chemistry*
D004273:DNA, Neoplasm
Tsitofliuorometricheskoe issledovanie épitelia sheĭki matki pri malignizatsii.