title: The fixed dilated pupil after cataract surgery--is it related to intraocular use of hypromellose?
abstract: Hypromellose can be used as a viscoelastic substance during cataract surgery. Two groups of patients, one group operated on using hypromellose, the other using sodium hyaluronate as a viscoelastic substance were followed up 2-6 months postoperatively. A total of 16.7% of the eyes operated on using hypromellose developed a non-reactive semidilated pupil whereas none of the eyes from the control group developed this phenomenon. It was concluded that there is a probable link between the intraocular use of hypromellose and abnormal pupils after cataract surgery.
authors.affiliation: Department of Ophthalmology, Salisbury District Hospital.
authors.forename: A K
authors.initials: AK
authors.lastname: Tan
authors.forename: R C
authors.initials: RC
authors.lastname: Humphry
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D002482:Cellulose / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D065347:Hypromellose Derivatives; D008297:Male; D008747:Methylcellulose / Q000031:analogs & derivatives*; D011184:Postoperative Period; D011446:Prospective Studies; D011680:Pupil / Q000187:drug effects*
chemical_list: D004338:Drug Combinations; D065347:Hypromellose Derivatives; D002482:Cellulose; D008747:Methylcellulose