title: Pharmacological modulation of 5-fluorouracil and its clinical implications: an overview.
abstract: Authors present an overview of the present knowledge in the field of biochemical modulation of 5-fluorouracil and its potential clinical applications. Interaction between 5-fluorouracil and several modulators, such as leucovorin, interferons, cisplatin, hydroxyurea, thymidine, methotrexate, and PALA are extensively analyzed.
authors.affiliation: Institute of Pharmacology, University of Palermo, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Gebbia
authors.forename: A
authors.initials: A
authors.lastname: Testa
authors.forename: N
authors.initials: N
authors.lastname: Borsellino
authors.forename: G
authors.initials: G
authors.lastname: Cannata
authors.forename: R
authors.initials: R
authors.lastname: Valenza
authors.forename: N
authors.initials: N
authors.lastname: Gebbia
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols; D004334:Drug Administration Schedule; D004347:Drug Interactions; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D005472:Fluorouracil