[Toxicity of levamisole in adjuvant chemotherapy for colorectal cancer].
We studied the levamisole toxic effects in adjuvant therapy for colorectal cancer. The therapy toxic effects on 127 patients were statistically more important in the levamisole-treated group compared to patients treated with folinic acid and 5-fluorouracil alone. Randomized studies in progress will demonstrate the real therapeutic value of levamisole.
Navarro-Carola
E
E
Service de médecine interne-oncologie, hôpital Saint-Antoine, Paris, France.
de Gramont
A
A
Louvet
C
C
Varette
C
C
Demuynck
B
B
Beerblock
K
K
Soubrane
D
D
Grangé
J D
JD
Krulik
M
M
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D007978:Levamisole / Q000009:adverse effects* / Q000627:therapeutic use; D012189:Retrospective Studies
D007978:Levamisole; D002955:Leucovorin; D005472:Fluorouracil
Toxicité du lévamisole dans la chimiothérapie adjuvante du cancer colorectal.