title: Differentiation of transiently ischemic from infarcted myocardium by thallium-201 exercises scintigram after active ergometer rehabilitation.
abstract: It has been frequently reported that while myocardial viability is neglected in conventional methods of diagnosis such as left ventriculography, ECG, and exercise thallium-201 myocardial scintigraphy (Ex-Tl), revascularization often results in improving left ventricular wall motility. In the present study, the authors contrived a method to accurately evaluate the viability of the myocardium by means of exercise rehabilitation, and tested the method in clinical cases. Among patients with myocardial infarction, we selected a patient with negative viability in the diseased area as determined by chronic ECG, left ventriculography (LVG), coronary angiography and Ex-Tl. This patient went through two weeks of active exercise rehabilitation gauged with an ergometer, and was then re-examined by Ex-Tl. After the evaluation, revascularization was performed for the patient who demonstrated viability of the infarcted myocardium in EX-Tl after rehabilitation, and significant improvement in contractility was shown in the chronic LVG. These findings indicate that our method of detecting potential viability of the infarcted myocardium is of clinical significance.
authors.affiliation: Department of Medical Engineering and Cardiology, Tohoku University, Sendai, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yambe
authors.forename: S
authors.initials: S
authors.lastname: Nitta
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Meguro
authors.forename: Y
authors.initials: Y
authors.lastname: Saijoh
authors.forename: S
authors.initials: S
authors.lastname: Naganuma
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: N
authors.initials: N
authors.lastname: Endoh
authors.forename: Y
authors.initials: Y
authors.lastname: Terasawa
authors.forename: Y
authors.initials: Y
authors.lastname: Katahira
mesh_terms: D016552:Ergometry; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000534:rehabilitation*; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000534:rehabilitation*; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes