Cortical magnetic and electric fields associated with voluntary finger movements.
Multichannel recordings of both movement-related magnetic fields (MRMFs) and movement-related cortical potentials (MRCPs) were simultaneously recorded in association with voluntary unilateral self-paced index finger abduction movement in two normal volunteers. 1) Slow magnetic field (readiness field; RF) can be detected several hundred msec before the movement onset, and its field distribution indicates the existence of the largest generator source over the contralateral primary motor area. Taken together with the vertex-maximal Bereitschaftspotential which corresponds to the earlier part of the RF, the complexity of this magnetic field suggested by relatively low correlation value in single dipole model indicates the co-activation of other underlying generators besides this largest dipole. 2) The utilization of MRMF with MRCP facilitates the separation of two distinct electrophysiological events in proximity to the movement onset, which are difficult to be determined by the technique of MRCP only. Those are the motor field (MF) and the movement evoked field I (MEFI) in MRMF, and the parietal peak motor potential (ppMP) and the frontal peak motor potential (fpMP) in MRCP, which occur approximately 20 and 100 msec after EMG onset, respectively. These two subcomponents may imply the culmination of motor cortex and sensory feedback activation, respectively. Combined study of MRMF and MRCP will provide better definition of cortical events related to voluntary movement than the study of either modality alone.
Nagamine
T
T
Department of Brain Pathophysiology, Kyoto University School of Medicine, Japan.
Toro
C
C
Balish
M
M
Deuschl
G
G
Wang
B
B
Sato
S
S
Shibasaki
H
H
Hallett
M
M
D000328:Adult; D002540:Cerebral Cortex / Q000502:physiology*; D003265:Contingent Negative Variation / Q000502:physiology; D004569:Electroencephalography; D004574:Electromagnetic Fields; D005385:Fingers / Q000294:innervation / Q000502:physiology*; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D009068:Movement / Q000502:physiology*