title: Persistent topographic quantitative EEG sequelae of chronic marihuana use: a replication study and initial discriminant function analysis.
abstract: In a previous pilot study using psychiatric patients we reported that daily marihuana users had significant elevations of (1) Absolute Alpha Power, (2) Relative Alpha Power, and (3) Interhemispheric Alpha Coherence over both frontal and frontal-central areas when contrasted with subjects who did not use marihuana. We referred to this phenomenon as Hyperfrontality of Alpha. The study presented here is a successful replication of our previous findings using new samples of subjects and identical methods. Post hoc analyses based on the combined sample from both studies suggest that variables of psychiatric diagnoses and medication did not bias our results. In addition, a discriminant function analysis using quantitative EEG variables as candidate predictors generated a 95% correct THC user versus nonuser classification accuracy which received a successful jackknife replication.
authors.affiliation: Psychiatry Department, Louisiana State University School of Medicine, Shreveport 71130-3932.
authors.forename: F A
authors.initials: FA
authors.lastname: Struve
authors.forename: J J
authors.initials: JJ
authors.lastname: Straumanis
authors.forename: G
authors.initials: G
authors.lastname: Patrick
mesh_terms: D000328:Adult; D000513:Alpha Rhythm; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D016002:Discriminant Analysis; D004569:Electroencephalography; D005544:Forecasting; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D002189:Marijuana Abuse / Q000503:physiopathology*; D001523:Mental Disorders; D009044:Motor Cortex / Q000503:physiopathology; D010865:Pilot Projects; D012815:Signal Processing, Computer-Assisted; D013826:Theta Rhythm