The effect of a 6-month cardiac rehabilitation programme on serum lipoproteins and apoproteins A1 and B and lipoprotein a.
One hundred and forty-two cardiac rehabilitation patients were followed up over a period of 6 months and the percentage change over time was recorded for various lipid fractions including apoprotein AI (apo AI), apoprotein B (apo B) and lipoprotein a (Lp(a)). Data were analysed to see if improvement in peak oxygen consumption (VO2) or changes in body weight were related to any of the above. A significant percentage change was found for peak VO2, ventilatory threshold, high-density lipoprotein cholesterol (HDLC) and triglyceride levels, total cholesterol (TC)/HDL ratio, apo AI, apo A/apo B ratio and Lp(a). Multiple regression analysis showed that alterations in the lipid fractions were not related to changes in physical fitness except in the case of TC levels which dropped independently of other measures. On multivariate analysis, Lp(a) correlated positively with both the Broca index and the use of drugs of the fibrate series.
Morris
R
R
Cardiac Rehabilitation Unit, Johannesburg City Health Department.
Digenio
A
A
Padayachee
G N
GN
Kinnear
B
B
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000534:rehabilitation; D015906:Angioplasty, Balloon, Coronary / Q000534:rehabilitation; D016632:Apolipoprotein A-I / Q000378:metabolism*; D001055:Apolipoproteins B / Q000378:metabolism*; D001026:Coronary Artery Bypass / Q000534:rehabilitation; D003327:Coronary Disease / Q000534:rehabilitation*; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D017270:Lipoprotein(a) / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000534:rehabilitation; D012044:Regression Analysis
D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D017270:Lipoprotein(a)