Towards defining receptors for L-tyrosine and L-dopa.
We postulate that in mammalian systems neurotransmitter and hormone-like functions of L-tyrosine (LT) and L-DOPA (LD) are mediated via specific membrane-bound and/or nuclear receptors. The structure and function of these receptors may represent an evolutionary continuum of regulatory proteins binding LT or LD in unicellular and lower multicellular organisms.
Slominski
A
A
Department of Pathology & Laboratory Medicine, Albany Medical College, NY 12208.
Paus
R
R
D000818:Animals; D002462:Cell Membrane; D002467:Cell Nucleus; D007980:Levodopa / Q000378:metabolism*; D017459:Receptors, Amino Acid / Q000502:physiology*; D017981:Receptors, Neurotransmitter / Q000502:physiology*; D014443:Tyrosine / Q000502:physiology*
D017459:Receptors, Amino Acid; D017981:Receptors, Neurotransmitter; C087658:levodopa receptor; C087659:tyrosine receptor; D014443:Tyrosine; D007980:Levodopa