title: 1,3-Diarylindan-2-carboxylic acids, potent and selective non-peptide endothelin receptor antagonists.
authors.affiliation: Research and Development Division, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406-0939.
authors.forename: J D
authors.initials: JD
authors.lastname: Elliott
authors.forename: M A
authors.initials: MA
authors.lastname: Lago
authors.forename: R D
authors.initials: RD
authors.lastname: Cousins
authors.forename: A
authors.initials: A
authors.lastname: Gao
authors.forename: J D
authors.initials: JD
authors.lastname: Leber
authors.forename: K F
authors.initials: KF
authors.lastname: Erhard
authors.forename: P
authors.initials: P
authors.lastname: Nambi
authors.forename: N A
authors.initials: NA
authors.lastname: Elshourbagy
authors.forename: C
authors.initials: C
authors.lastname: Kumar
authors.forename: J A
authors.initials: JA
authors.lastname: Lee
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D065128:Endothelin Receptor Antagonists; D016232:Endothelins / Q000737:chemistry / Q000502:physiology; D007189:Indans / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D051381:Rats; D017466:Receptors, Endothelin / Q000378:metabolism
chemical_list: D065128:Endothelin Receptor Antagonists; D016232:Endothelins; D007189:Indans; D017466:Receptors, Endothelin; C087551:1H-Indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1S,2R,3S)-