Polyglucosan bodies in brain tissue: a systematic study.
The relation between age, sex and presence of polyglucosan bodies in the brain has been systematically studied in 64 patients who did not suffer from neurological brain disorders and in 2 cases with Lafora's disease. In the normal brain the number of polyglucosan bodies is related to increasing age. Under the age of 40, polyglucosan bodies can be found sporadically in cases without a neurological disorder, but in the cases of Lafora's disease their number is uncomparatively higher. A sex relation has not been found.
Busard
H L
HL
Institute of Neurology, University Hospital Nijmegen, The Netherlands.
Span
J P
JP
Renkawek
K
K
Renier
W O
WO
Gabreëls
F J
FJ
Slooff
J L
JL
Van 't Hof
M A
MA
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004831:Epilepsies, Myoclonic / Q000473:pathology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology*; D005936:Glucans / Q000032:analysis*; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013702:Temporal Lobe / Q000473:pathology*
D005936:Glucans; C083094:polyglucosan