[Extramedullary blastic transformation in chronic granulocytic leukemia].
A patient with Ph1(Philadelphia chromosome) positive chronic granulocytic leukemia and extramedullary blast transformation (crisis) in lymph nodes of the neck and axillae which appeared after a 4-year treatment with busulfan, is presented. Biopsy of lymph node and histopathological examination showed lymphoblastic infiltration. The patient was treated with radiotherapy and chemotherapy with protocol COP. He survived 7 months and expired due to renal insufficiency.
Vidović
A
A
Institut za hematologiju UKC, Beograd.
Janković
G
G
Suvajdzić
N
N
Colović
M
M
D001752:Blast Crisis / Q000473:pathology*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010677:Philadelphia Chromosome
Ekstramedulski blastni preobrazaj u hronicnoj granulocitnoj leukemiji.