title: Response of urinary sodium excretion to elevated intravesical pressure.
abstract: This experimental study was designed to investigate the possibility of an interaction between elevated intravesical pressure and urinary sodium excretion. Fourteen male New Zealand rabbits were used. After performing a ureterocutaneous diversion, urinary sodium excretion was measured in two situations: with the bladder empty and with the bladder overdistended and an intravesical pressure of 60 cm H2O. There was a significant decrease in urinary sodium excretion at an elevated intravesical pressure. The urinary sodium excretion returned to normal after relief of the pressure. The results suggest the existence of a neurogenic pathway activated by the elevated intravesical pressure.
authors.affiliation: Department of Urology, Hippokration General Hospital, Athens, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Dangas
authors.forename: E
authors.initials: E
authors.lastname: Parashou
authors.forename: M
authors.initials: M
authors.lastname: Lymberi
authors.forename: P
authors.initials: P
authors.lastname: Kehayas
mesh_terms: D000818:Animals; D007668:Kidney / Q000294:innervation / Q000502:physiology; D008297:Male; D009318:Natriuresis / Q000502:physiology*; D009424:Nervous System Physiological Phenomena; D011312:Pressure; D011817:Rabbits; D012018:Reflex / Q000502:physiology; D012964:Sodium / Q000652:urine*; D001743:Urinary Bladder / Q000294:innervation / Q000502:physiology*
chemical_list: D012964:Sodium