Fine needle aspiration of invasive cribriform carcinoma with benign osteoclast-like giant cells of histiocytic origin. A case report.
We report the fine needle aspiration findings, with histologic confirmation, of a case of invasive cribriform carcinoma of the breast with benign osteoclast-like giant cells. We suggest that this diagnosis be considered when low to moderate grade malignant epithelial cells and numerous benign giant cells are seen in fine needle aspirates of the breast. We also confirmed immunohistochemically the histiocytic origin of the benign giant cells.
Phillipson
J
J
Department of Pathology, Olive View/University of California, Los Angeles Medical Center, Sylmar 91342.
Ostrzega
N
N
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D015726:Giant Cells / Q000473:pathology*; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D015411:Mastectomy, Modified Radical; D009361:Neoplasm Invasiveness; D010010:Osteoclasts / Q000473:pathology*; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; C067980:CD68 antigen, human; D000097382:CD68 Molecule