Changes in serum C-reactive protein levels in dogs with various disorders and surgical traumas.
The serum levels of C-reactive protein (CRP) produced as an inflammatory response in dogs with various disorders and surgical traumas were measured by enzyme-linked immunoabsorbent assay and slide reversed passive latex agglutination test (RPLA). The CRP levels were greatly increased 1-2 days after surgery in most of the dogs (n = 29) subjected to surgery. These levels had markedly decreased by the time the sutures were removed. In dogs with various disorders (n = 58), the serum CRP levels at first diagnosis were high in infectious diseases. In dogs from which paired serum samples were examined, the serum CRP usually showed a decrease with improvement in the condition (n = 11) or a terminal increase (n = 4) but, conversely, some showed an increase with improvement in the condition (n = 3).
Yamamoto
S
S
Department of Immunology, Faculty of Environmental Health, Azabu University, Kanagawa, Japan.
Shida
T
T
Miyaji
S
S
Santsuka
H
H
Fujise
H
H
Mukawa
K
K
Furukawa
E
E
Nagae
T
T
Naiki
M
M
D000818:Animals; D002097:C-Reactive Protein / Q000096:biosynthesis*; D004283:Dog Diseases / Q000097:blood* / Q000601:surgery; D004285:Dogs / Q000293:injuries / Q000601:surgery*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D007841:Latex Fixation Tests / Q000662:veterinary; D007958:Leukocyte Count; D011184:Postoperative Period; D013245:Sterilization, Reproductive / Q000662:veterinary; D014947:Wounds and Injuries / Q000097:blood / Q000662:veterinary
D002097:C-Reactive Protein