[The effect of different concentrations of strophanthin K on the chrono- and inotropic parameters of the isolated myocardial preparation and its oxygen consumption].
The contraction rate and force of the myocardium and its oxygen consumption under the action of various strophanthin-K concentrations for 10 min after its administration into the cuvette were studied in the experiments on the isolated frog atria contracting in the isometric mode. There was a two-phase response of cardiac glycoside, which depended on the time of its action and concentration.
Lemkina
S M
SM
D000818:Animals; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D006339:Heart Rate / Q000187:drug effects*; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000187:drug effects*; D009206:Myocardium / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects*; D011895:Rana ridibunda; D013328:Strophanthins / Q000008:administration & dosage*; D013997:Time Factors
D013328:Strophanthins; C029082:strophanthin K
Vliianie razlichnykh kontsentratsiĭ strofantina K na khronoinotropnye parametry izolirovannogo preparata miokarda i potreblenie im kisloroda.