Long-term follow-up of 121 patients with benign fasciculations.
Using the case records of Mayo Clinic patients, 121 patients with a diagnosis of benign fasciculations were identified. All had a normal neurological examination and normal electrophysiological studies, except for fasciculation potentials. Interviews by telephone were conducted 2 to 32 years after diagnosis. None of the patients developed symptomatic motor neuron disease. Forty individuals were in health care careers. A subset of 19 patients described acute onset of fasciculations following a viral infection. Benign fasciculations are not a preclude to progressive motor neuron disease.
Blexrud
M D
MD
Mayo Clinic, Department of Neurology, Rochester, MN 55905.
Windebank
A J
AJ
Daube
J R
JR
D000328:Adult; D000368:Aged; D005207:Fasciculation / Q000150:complications / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000209:etiology