Circulatory effects of vasoconstrictors combined with local anesthetics.
Vasoconstrictors are clinically used as adjuvants to local anesthetics to improve anesthetic action and to minimize local bleeding. Accidental intravascular injection or rapid systemic absorption of vasoconstrictors can induce a number of potentially life-threatening circulatory risks, which are described in this paper.
Jage
J
J
Clinic of Anesthesiology, University of Mainz, Germany.
D000766:Anesthesia, Dental / Q000009:adverse effects; D000779:Anesthetics, Local / Q000493:pharmacokinetics / Q000494:pharmacology*; D000075202:Contraindications; D017742:Dental Care for Chronically Ill; D004338:Drug Combinations; D004347:Drug Interactions; D004837:Epinephrine / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology; D008619:Mepivacaine / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D014662:Vasoconstrictor Agents / Q000494:pharmacology*
D000779:Anesthetics, Local; D004338:Drug Combinations; D014662:Vasoconstrictor Agents; D008012:Lidocaine; D008619:Mepivacaine; D009638:Norepinephrine; D004837:Epinephrine