title: [Subglottal stenosis as the initial manifestation in Wegener's disease].
abstract: A 21-year-old man with 3-month history of hoarseness and dyspnea was suspected to have Wegener's granulomatosis with initially appearing in the trachea. In spite of unspecific biopsies, the clinicopathological picture and the high titles of anticytoplasmic autoantibodies (ACPA) confirmed the diagnosis. The early treatment with cyclophosphamide impeded the evolution to graver systemic forms of the disease.
authors.affiliation: Servicio de ORL, Hospital Universitario Arrixaca, Murcia.
authors.forename: F P
authors.initials: FP
authors.lastname: García-Ortega
authors.forename: F
authors.initials: F
authors.lastname: Herrero
authors.forename: L
authors.initials: L
authors.lastname: Pretel
authors.forename: F
authors.initials: F
authors.lastname: Sánchez-Celemin
mesh_terms: D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005931:Glottis / Q000503:physiopathology; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007829:Laryngostenosis / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D007830:Larynx / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D014832:Voice Disorders / Q000209:etiology
chemical_list: D003520:Cyclophosphamide
vernacular_title: Estenosis subglótica como primera manifestación de la enfermedad de Wegener.