title: Identification and localization of G(i) alpha 3 in the clonal adipocyte cell lines HGFu and Ob17.
abstract: The HGFu and Ob17 cell lines, derived from adipose tissue of lean (+/?) and ob/ob mice, respectively, express several G-protein peptides. Investigation of the expression and subcellular localization of the G(i) alpha 3 subunit showed that this peptide is associated with the Golgi apparatus. These findings indicate a role for this subunit in vesicular traffic and are in agreement with the view of the adipocyte as a secretory cell.
authors.affiliation: Department of Pathology, University of Ottawa, ON, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Cadrin
authors.forename: N
authors.initials: N
authors.lastname: McFarlane-Anderson
authors.forename: N
authors.initials: N
authors.lastname: Bégin-Heick
mesh_terms: D017667:Adipocytes / Q000737:chemistry*; D000818:Animals; D002451:Cell Compartmentation; D002454:Cell Differentiation; D002999:Clone Cells; D005455:Fluorescent Antibody Technique; D019204:GTP-Binding Proteins / Q000302:isolation & purification*; D006056:Golgi Apparatus / Q000737:chemistry*; D051379:Mice; D008820:Mice, Obese
chemical_list: D019204:GTP-Binding Proteins