[Administration of naloxone to newborn infants at obstetric departments in Norway].
Recommendations for the dosage of naloxone to reverse opiate depression in neonates were revised by the American Academy of Pediatrics in 1989. In order to ascertain the extent to which these new recommendations have been implemented in Norway, we sent questionnaires to the maternity centres by mail. The responses from 60 different centres covered 88% of the total births in Norway in 1991. The dosages of naloxone used varied from 0.01-0.1 mg/kg, and the reported frequency of use in newborns varied between < 10-50%. Similarly, the use of opiate analgesia in parturients varied considerably, with frequencies ranging from < 10 to 90%. We conclude that there is wide variation in use of naloxone to treat neonates in Norway and in the prescribed dose, and suggest that most centres should re-evaluate the dose. Some centres also need to re-evaluate the rate of usage.
Fagerli
I
I
Neonatalseksjonen, Barneklinikken, Rikshospitalet, Oslo.
Hansen
T W
TW
D016362:Analgesia, Obstetrical / Q000706:statistics & numerical data*; D000075202:Contraindications; D004363:Drug Utilization; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008614:Meperidine / Q000008:administration & dosage / Q000009:adverse effects; D009270:Naloxone / Q000008:administration & dosage* / Q000009:adverse effects; D009664:Norway; D009775:Obstetrics and Gynecology Department, Hospital / Q000706:statistics & numerical data*; D011247:Pregnancy; D012119:Respiration / Q000187:drug effects; D011795:Surveys and Questionnaires
D009270:Naloxone; D008614:Meperidine
Bruk av naloxon til nyfødte ved fødeavdelinger i Norge.