Decreased postprandial thermogenesis and fat oxidation but increased fullness after a high-fiber meal compared with a low-fiber meal.
The effect of a high-fiber (4.7 g/MJ) and an isoenergetic low-fiber (1.7 g/MJ) meal on 6-h postprandial thermogenesis, substrate metabolism, hormones, and satiety was investigated in 10 healthy, normal-weight male subjects. Diet-induced thermogenesis (DIT) was significantly reduced after the high-fiber meal (416.4 +/- 28.6 kJ/6 h) compared with the low-fiber meal (498.5 +/- 23.1 kJ/6 h; ANOVA: P < 0.0001), as was postprandial fat oxidation (P < 0.0001). The difference in DIT was correlated with the different palatability of the test meal (r = 0.89, P < 0.01). No differences were observed in plasma concentrations of glucose, insulin, norepinephrine, epinephrine, or gastrointestinal hormones, but C-peptide increased less (P < 0.05) and nonesterified fatty acids decreased more (P < 0.05) after the high-fiber meal. Finally, fullness was increased and desire to eat decreased after the high-fiber meal (P < 0.0001). In conclusion, a high-fiber meal decreased DIT and fat oxidation but increased fullness compared with a low-fiber meal.
Raben
A
A
Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
Christensen
N J
NJ
Madsen
J
J
Holst
J J
JJ
Astrup
A
A
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001831:Body Temperature / Q000502:physiology*; D050260:Carbohydrate Metabolism; D004043:Dietary Fiber; D004734:Energy Metabolism / Q000502:physiology; D005223:Fats / Q000378:metabolism*; D005227:Fatty Acids / Q000097:blood; D006728:Hormones / Q000097:blood; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D008962:Models, Theoretical; D010084:Oxidation-Reduction; D011506:Proteins / Q000378:metabolism; D012527:Satiation
D001786:Blood Glucose; D004043:Dietary Fiber; D005223:Fats; D005227:Fatty Acids; D006728:Hormones; D007773:Lactates; D011506:Proteins; D019344:Lactic Acid