beta-Carbolines from the blue-green alga Dichothrix baueriana.
Three new chlorine-containing beta-carbolines, bauerines A-C (1-3), have been isolted from the terrestrial blue-green alga Dichothrix baueriana GO-25-2, and identifying mass and nmr spectral analysis. The alkaloids show activity against herpes simplex virus type 2.
Larsen
L K
LK
Department of Chemistry, University of Hawaii, Honolulu.
Moore
R E
RE
Patterson
G M
GM
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002243:Carbolines / Q000302:isolation & purification* / Q000494:pharmacology; D002478:Cells, Cultured; D000458:Cyanobacteria / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D018258:Herpesvirus 2, Human / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008907:Mink; D014407:Tumor Cells, Cultured
D000998:Antiviral Agents; D002243:Carbolines; C087543:bauerine A; C087544:bauerine B; C087545:bauerine C