[Effect of capoten on hemostasis of patients with hypertension].
The effects of capoten on hemostasis were studied in 63 patients with Stages I and II hypertensive disease in relation to the hemodynamic type and severity of the disease. Thrombophilia was revealed just at the onset of the disease mainly due to hemostatic endothelial dysfunction which progresses with the hemodynamic development of hypertensive disease. Capoten optimizes hemostatic parameters by affecting endothelial function, which serves an additional mechanism of the antihypertensive effect of the drug. Supplementary techniques affecting the rheological properties should be used in the treatment of hypertensives with moderate-to-serve courses along with resistive hemodynamics.
Nekrutenko
L A
LA
Tuev
A V
AV
Tschekotov
V V
VV
D000328:Adult; D002216:Captopril / Q000494:pharmacology* / Q000627:therapeutic use*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006487:Hemostasis / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D012720:Severity of Illness Index
D002216:Captopril
Optimizatsiia pod vliianiem kapotena sostoianiia gemostaza u bolńykh gipertonicheskoĭ boleznìu.