title: Different pattern of IgE binding to chicken egg yolk between patients with inhalant allergy to birds and food-allergic children.
abstract: IgE binding antigens in budgerigar, canary and parrot serum were analyzed by immunoblotting. With 4 sera from patients with a respiratory allergy to birds, a closely related pattern of IgE binding to SDS-PAGE separated sera of the 3 birds was found. In all 3 bird sera a major IgE binding structure was present with a MW of about 60 kD. The pattern of IgE binding to SDS-PAGE separated egg yolk in sera from the patients allergic to birds, was different from sera of food-allergic children. Whereas in the bird-allergic patients major IgE binding occurred to a 60 kD component in egg yolk, IgE from food-allergic children was preferentially bound to a 35-kD structure in egg yolk.
authors.affiliation: Department of Clinical Chemistry, University Hospital Dijkzigt, The Netherlands.
authors.forename: A W
authors.initials: AW
authors.lastname: van Toorenenbergen
authors.forename: M I
authors.initials: MI
authors.lastname: Huijskes-Heins
authors.forename: R
authors.initials: R
authors.lastname: Gerth van Wijk
mesh_terms: D000328:Adult; D000818:Animals; D001717:Birds / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004530:Egg Yolk / Q000276:immunology; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood* / Q000276:immunology; D007223:Infant; D008970:Molecular Weight
chemical_list: D007073:Immunoglobulin E