A rich complexity emerges in phototransduction.
Over the past two decades there has been an explosive growth in our understanding of phototransduction, leading to the development of a comprehensive scheme for the process. On the basis of this scheme the finer details of the process are being elucidated. Additional protein components and pathways have been identified, successful quantitative models of parts of the process have been developed, and a detailed understanding of the molecular basis of physiological function has begun to emerge. Here we summarize the most recent developments.
Koutalos
Y
Y
Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2185.
Yau
K W
KW
D000818:Animals; D002118:Calcium / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D005246:Feedback; D006801:Humans; D008959:Models, Neurological; D017949:Retinal Cone Photoreceptor Cells / Q000502:physiology*; D012164:Retinal Diseases / Q000235:genetics / Q000503:physiopathology; D012374:Rod Cell Outer Segment / Q000502:physiology*; D015398:Signal Transduction
D006152:Cyclic GMP; D002118:Calcium