Parvalbumin as an anatomical marker for discrete subregions of the ambiguus complex in the rat.
The topography of parvalbumin-immunoreactive neurons within the ventrolateral medulla of rats was investigated. Parvalbumin is a member of the 'EF-hand' family of Ca-binding proteins and is present in certain cell types within the central nervous system (fast-firing neurons with high metabolic rates). Parvalbumin-immunoreactive neurons were located in discrete rostrocaudal divisions of the ambiguus complex corresponding to regions containing respiratory-related neurons. Based on the location of physiologically characterized respiratory-related neurons reported in the literature, parvalbumin immunoreactivity does not appear to distinguish inspiratory- from expiratory-related neurons.
Cox
M
M
Department of Pathology, University of Sydney, NSW, Australia.
Halliday
G M
GM
D000818:Animals; D015415:Biomarkers; D007150:Immunohistochemistry; D008297:Male; D008526:Medulla Oblongata / Q000033:anatomy & histology* / Q000166:cytology / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D010320:Parvalbumins / Q000276:immunology / Q000378:metabolism*; D051381:Rats; D011920:Rats, Inbred WF
D015415:Biomarkers; D010320:Parvalbumins