title: Relapse of herpes simplex encephalitis after acyclovir therapy.
abstract: A case of herpes simplex encephalitis in a previously healthy 17-month-old girl relapsing 1 week after completion of a 10-day acyclovir therapy is described. The child responded favourably to a second 10-day course with acyclovir. The time of relapse and the satisfactory response to a second course of acyclovir treatment indicate that the first course of therapy was inadequate for eradication of herpes simplex virus infection.
authors.affiliation: First Department of Paediatrics, University of Athens, St. Sophie, Children's Hospital, Greece.
authors.forename: P
authors.initials: P
authors.lastname: Nicolaidou
authors.forename: N
authors.initials: N
authors.lastname: Iacovidou
authors.forename: S
authors.initials: S
authors.lastname: Youroukos
authors.forename: T
authors.initials: T
authors.lastname: Liacopoulou-Tsitsipi
authors.forename: C
authors.initials: C
authors.lastname: Kattamis
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004660:Encephalitis / Q000188:drug therapy*; D005260:Female; D006561:Herpes Simplex / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D012008:Recurrence
chemical_list: D000212:Acyclovir