Thrombosis-inducing activity--a factor which appears in plasma of patients with allergic asthma during attack.
Thrombosis-inducing activity (TIA) is a factor which was recently identified in plasma from patients with advanced lung cancer and acute respiratory tract infection. In the present study, TIA was measured during periods of attack and nonattack in patients with the allergic and nonallergic type of asthma and pulmonary emphysema with an asthmatic component. In the allergic type of asthma, the attack was accompanied by the appearance of TIA, but when the attack ended it disappeared from plasma. In the nonallergic type of asthma and emphysema with an asthmatic component, TIA remained negative even during the attack. These observations indicate that TIA has some correlations with allergic asthma.
Nakanishi
M
M
Second Department of Internal Medicine, Fukuoka University Medical School, Japan.
Takayama
M
M
Ishii
H
H
Ogino
H
H
Kawasaki
M
M
Hayashi
S
S
Yoshida
M
M
Yagawa
K
K
D000328:Adult; D000368:Aged; D001249:Asthma / Q000097:blood*; D001685:Biological Factors / Q000276:immunology*; D001779:Blood Coagulation Factors / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000097:blood; D013927:Thrombosis / Q000276:immunology*
D001685:Biological Factors; D001779:Blood Coagulation Factors