title: [The effect of a Bordetella live vaccine on the occurrence and manifestation of atrophic rhinitis suum and the aerogenous infection burden in field strains of the agent].
abstract: A field study was carried out in a large scale unit for swine breeding and fattening with the object to influence the high morbidity rate of Atrophic Rhinitis and pneumonia with the help of a Bordetella live vaccine. The results show that it is possible to decrease the infectious pressure by B. bronchiseptica and to reduce the pathomorphological signs of Atrophic Rhinitis in consequence of the application of the live vaccine. The pathologic-anatomical investigations of nasal turbinates in immunized slaughtered fattening pigs show a significant lower morbidity concerning Atrophic Rhinitis and a higher percentage of pigs without changes at conchae nasales and septum nasi. We find also a lower contamination of the air with B. bronchiseptica field strains during vaccine application. The results also explain that a high infectious pressure by B. bronchiseptica and the possibility of communication between unvaccinated and vaccinated groups of pigs counteract a better efficiency of the vaccine. The decrease of the morbidity rate of Atrophic Rhinitis appears so much more important because toxicogenic Pasteurella multocida strains were isolated from nasal swabs of vaccinated pigs during the investigations. But these strains influenced the Atrophic Rhinitis frequency only accidentally. All results as a whole point out that in pig houses with a high animal density one has to pay more attention to virulent B. bronchiseptica strains than it was been done till now.
authors.affiliation: Institut für Tierhygiene, Veterinärmedizinischen Fakultät, Universität Leipzig.
authors.forename: U
authors.initials: U
authors.lastname: Ehser
authors.forename: G
authors.initials: G
authors.lastname: Mehlhorn
authors.forename: H
authors.initials: H
authors.lastname: Mietke
mesh_terms: D000818:Animals; D001427:Bacterial Toxins / Q000096:biosynthesis; D001428:Bacterial Vaccines; D001885:Bordetella Infections / Q000517:prevention & control / Q000662:veterinary*; D016950:Bordetella bronchiseptica / Q000276:immunology* / Q000472:pathogenicity; D005260:Female; D011247:Pregnancy; D012222:Rhinitis, Atrophic / Q000517:prevention & control / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary
chemical_list: D001427:Bacterial Toxins; D001428:Bacterial Vaccines
vernacular_title: Untersuchungen zum Einfluss eines Bordetellen-Lebendimpfstoffes auf das Auftreten und die Ausprägung der Rhinitis atrophicans suum sowie den aerogenen Infektionsdruck durch Feldstämme des Erregers.