title: The manufacture and molecular characterization of phosphorothioate deoxynucleotides for use as antisense therapeutics in human clinical trials.
authors.affiliation: Lynx Therapeutics, Inc., Foster City, CA 94404.
authors.forename: B J
authors.initials: BJ
authors.lastname: Bergot
authors.forename: M
authors.initials: M
authors.lastname: Foy
authors.forename: C
authors.initials: C
authors.lastname: Hansen
authors.forename: K
authors.initials: K
authors.lastname: Fearon
authors.forename: J
authors.initials: J
authors.lastname: Frediani
authors.forename: B
authors.initials: B
authors.lastname: Hirschbein
mesh_terms: D017321:Clinical Trials, Phase I as Topic; D016373:DNA, Antisense / Q000138:chemical synthesis* / Q000235:genetics / Q000627:therapeutic use; D003854:Deoxyribonucleotides / Q000737:chemistry* / Q000235:genetics / Q000627:therapeutic use; D005786:Gene Expression Regulation; D016158:Genes, p53; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D013873:Thionucleotides / Q000138:chemical synthesis* / Q000235:genetics / Q000627:therapeutic use
chemical_list: D016373:DNA, Antisense; D003854:Deoxyribonucleotides; D013873:Thionucleotides