[Effect of treatment with propranolol or pindolol on the left ventricular myocardium mass in patients with slight essential arterial hypertension].
The effect was studied of 8 weeks of treatment with propranolol and pindolol on the left-ventricular myocardium mass, left-ventricular myocardium mass index, plasma renin activity, and serum aldosterone and total catecholamine concentrations. The studies were carried out in 72 patients with essential arterial hypertension of slight degree. A statistically significant decrease was shown of the left-ventricular myocardium mass, left-ventricular myocardium mass index, plasma renin activity, and aldosterone concentration in all studied patients. A decrease of total catecholamine concentration appeared in patients treated with propranolol. Weaker effect of pindolol on the studied parameters may be connected with its intrinsic sympathicomimetic activity. A correlation was shown between the decrease of the left-ventricular myocardium mass, and the decrease of systolic arterial blood pressure.
Haczyński
J
J
Katedry i Kliniki Kardiologii Ak. Med., Wrocławiu.
Spring
A
A
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010869:Pindolol / Q000627:therapeutic use*; D011433:Propranolol / Q000627:therapeutic use*
D011433:Propranolol; D010869:Pindolol
Wpływ leczenia propranololem lub pindololem na mase mieśnia lewej komory serca u chorych na nadciśnienie tetnicze pierwotne stopnia lekkiego.