title: Hepatocellular carcinoma associated with chronic Schistosoma mansoni infection in a chimpanzee.
abstract: Hepatocellular carcinoma associated with chronic Schistosoma mansoni infection in a chimpanzee, estimated to be a 12-year-old and born in West Africa, is reported. The hepatic tumor appeared as a solitary firm nodule, and histological examination revealed well-differentiated hepatocellular carcinoma with a trabecular pattern. Hepatitis B virus and hepatitis C virus infections were excluded by serological testing in that animal. This is the first report of hepatocellular carcinoma in the chimpanzee with schistosomiasis.
authors.affiliation: Department of Pathology, National Institute of Health, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Abe
authors.forename: N
authors.initials: N
authors.lastname: Kagei
authors.forename: Y
authors.initials: Y
authors.lastname: Teramura
authors.forename: H
authors.initials: H
authors.lastname: Ejima
mesh_terms: D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D002908:Chronic Disease; D005260:Female; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D002679:Pan troglodytes; D012555:Schistosomiasis mansoni / Q000150:complications / Q000473:pathology / Q000662:veterinary*