Acetazolamide in dominant cystoid macular dystrophy. A pilot study.
Eight patients (four men, four women), with low visual acuity caused by autosomal dominant cystoid macular dystrophy, were treated daily with oral 250 mg dose acetazolamide. Treatment ranged from two to 17 months. None of these eight patients had improvement of visual acuity of more than 0.1.


CONCLUSIONS
Treatment with 250 mg acetazolamide appears not to be an effective therapy for cystoid macular oedema in dominant cystoid macular dystrophy. The electroretinography b-wave/a-wave ratio was normal. The primary lesion in dominant cystoid macular dystrophy remains obscure.
Pinckers
A
A
Institute of Ophthalmology, University of Nijmegen, The Netherlands.
Cruysberg
J R
JR
Kremer
H
H
Aandekerk
A L
AL
D000086:Acetazolamide / Q000008:administration & dosage / Q000627:therapeutic use*; D000284:Administration, Oral; D000328:Adult; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008268:Macular Degeneration / Q000188:drug therapy* / Q000235:genetics*; D008269:Macular Edema / Q000188:drug therapy* / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D016896:Treatment Outcome; D014786:Vision Disorders / Q000188:drug therapy; D014792:Visual Acuity / Q000187:drug effects
D000086:Acetazolamide