title: Biliary cystadenocarcinoma arising in a cystadenoma. Report of a case diagnosed by fine needle aspiration cytology.
abstract: Hepatic cyst fluid cytology tends to yield disappointing results. We report a case of a 56-year-old woman with a biliary cystadenocarcinoma diagnosed by fine needle aspiration cytology. Computed tomography scans had shown a solitary, unilocular hepatic cyst over a five-year period. There was a recent increase in the size and development of a mural echogenic focus. Cytologic examination revealed clusters of malignant glandular cells in a background of cellular debris and mucinophages. The resected specimen confirmed the presence of an adenocarcinoma arising from malignant transformation of a preexisting cystadenoma.
authors.affiliation: Department of Pathology, National University Hospital, National University of Singapore.
authors.forename: A
authors.initials: A
authors.lastname: Wee
authors.forename: B
authors.initials: B
authors.lastname: Nilsson
authors.forename: J Y
authors.initials: JY
authors.lastname: Kang
authors.forename: L K
authors.initials: LK
authors.lastname: Tan
authors.forename: A
authors.initials: A
authors.lastname: Rauff
mesh_terms: D002759:Adenoma, Bile Duct / Q000473:pathology*; D001707:Biopsy, Needle; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D003536:Cystadenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D003537:Cystadenoma / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D002272:Carcinoembryonic Antigen