title: Candida zeylanoides causing candidiasis as tinea cruris.
abstract: Candida zeylanoides caused candidiasis as tinea cruris in 4 cases. Candida zeylanoides were characterized by good growth of the strain in malt medium, potato dextrose agar and Sabourard's agar. Their colony was milky white and greasy with smooth surface. The diameter of the colony reaches 12 mm within a week. As candida type pseudohyphae but not hyphae, they do not produce ascospore and bolospore. Carbon sources fermentation showed positive results. Nitrogen sources assimilation agar (KNO3) negative, arbutin agar negative, nonvitamin medium positive. G+C mol% value of their DNA was 51.24. Animal experiment showed that guinea pigs were infected by Candida zeylanoides. The main feature of candidiasis as tinea cruris caused by the strain was pink infiltrative erythema with clear margin, a lot of grain-sized papules, a few vesicles, and thin scales. The disease can be cured by preparation of ketoconazole.
authors.affiliation: Department of Dermatology, Changzheng Hospital, Shanghai.
authors.forename: W Q
authors.initials: WQ
authors.lastname: Liao
authors.forename: Z G
authors.initials: ZG
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Guo
authors.forename: J Z
authors.initials: JZ
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000818:Animals; D002175:Candida / Q000254:growth & development / Q000302:isolation & purification*; D002177:Candidiasis / Q000188:drug therapy / Q000382:microbiology*; D003470:Culture Media; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D014005:Tinea / Q000382:microbiology*
chemical_list: D003470:Culture Media; D007654:Ketoconazole