Studies on the hypocalcemic actions of salmon calcitonin and ultimobranchial gland extracts in the freshwater teleost Cyprinus carpio.
A single injection of synthetic salmon calcitonin (sCT) or homologous ultimobranchial gland (UBG) extract caused a significant reduction in total and ultrafiltrable plasma Ca2+ in a freshwater teleost, Cyprinus carpio. A time-bound analysis on the effect of sCT or UBG extract caused a short-duration hypocalcemia and the response was more pronounced in fish kept in low-Ca2+ water. Sexually immature fish showed a greater response than did mature fish. In all the studies the protein-bound Ca2+ fraction remained unaffected. The observation thus indicate a potent hypocalcemic role of calcitonin or UBG in freshwater common carp under laboratory conditions.
Chakrabarti
P
P
Department of Zoology, University of Kalyani, India.
Mukherjee
D
D
D000818:Animals; D002116:Calcitonin / Q000009:adverse effects* / Q000494:pharmacology; D002118:Calcium / Q000097:blood / Q000378:metabolism; D002347:Carps / Q000378:metabolism*; D005260:Female; D006996:Hypocalcemia / Q000097:blood / Q000139:chemically induced* / Q000378:metabolism; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood; D013997:Time Factors; D014020:Tissue Extracts / Q000009:adverse effects* / Q000032:analysis / Q000494:pharmacology; D014460:Ultimobranchial Body / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology
D014020:Tissue Extracts; D002116:Calcitonin; D012964:Sodium; D011188:Potassium; D002118:Calcium