title: An improved ocular perfusion system.
abstract: We describe the design, construction and testing of an improved ocular perfusion system for outflow facility measurement. The essential feature of the system is the measurement of a differential pressure across a calibrated length of tubing, which provides a stable and accurate reading of facility and hence also of flowrate. Perfusion of calibrated lengths of tubing showed excellent accuracy, while perfusions of enucleated eyes showed very low noise levels. The system is relatively inexpensive, easy to construct and maintain, insensitive to vibrations and other noise, and accurate. It is therefore felt to be superior to conventional "hanging bucket" ocular perfusion systems.
authors.affiliation: Department of Mechanical Engineering, University of Toronto, Ontario, Canada.
authors.forename: C R
authors.initials: CR
authors.lastname: Ethier
authors.forename: P
authors.initials: P
authors.lastname: Ajersch
authors.forename: R
authors.initials: R
authors.lastname: Pirog
mesh_terms: D000818:Animals; D001082:Aqueous Humor / Q000502:physiology*; D002417:Cattle; D004867:Equipment Design; D006801:Humans; D009799:Ocular Physiological Phenomena; D010477:Perfusion / Q000295:instrumentation / Q000379:methods*