Effect of otologic drill noise on ABR thresholds in a guinea pig model.
The noise generated by the otologic drill has been implicated as a cause of sensorineural hearing loss after ear surgery. However, clinical studies on this subject are contradictory and difficult to interpret. Therefore a guinea pig model was used to study whether the level of noise generated by the otologic drill can cause threshold shifts in the auditory brainstem response (ABR). The source noise was a recording obtained during a human cadaver mastoidectomy using a microphone and an accelerometer. Ten female Topeka-strain guinea pigs were exposed to the recorded drill noise for a period of 55 minutes. Exposure included both air-conducted energy from a speaker and bone-conducted energy from a bone vibrator applied directly to the skull. ABR threshold measurements were taken pre-exposure (baseline), immediately after exposure, and at weekly intervals thereafter for 3 weeks. Three control animals were subjected to the same procedure without the sound exposure. A significant threshold shift (p < 0.0001) was seen for each frequency tested (2, 4, 8, 16, 20, and 32 kHz) immediately after exposure to noise in all experimental animals. Thresholds returned to baseline within 3 weeks. We conclude that the level of noise generated by the otologic drill in mastoid surgery can cause a temporary threshold shift in this guinea pig model.
Suits
G W
GW
Department of Otolaryngology-Head and Neck Surgery, Oregon Hearing Research Center, Oregon Health Sciences University, Portland 97201.
Brummett
R E
RE
Nunley
J
J
D000704:Analysis of Variance; D000818:Animals; D001844:Bone Conduction / Q000502:physiology; D003051:Cochlea / Q000502:physiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006168:Guinea Pigs; D006319:Hearing Loss, Sensorineural / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D008416:Mastoid / Q000601:surgery; D009622:Noise / Q000009:adverse effects*; D010036:Otolaryngology / Q000295:instrumentation*; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D012684:Sensory Thresholds / Q000502:physiology; D013997:Time Factors