Multiple benign stromal cell tumours of the small bowel.
A rare case of multiple small intestinal stromal cell tumours is described in a 79 year old woman who presented with melaena and anaemia. At surgery, about 40 lesions were noted on the serosal surface of the small intestine, the largest of these tumours being located in the mid-jejunum. This lesion showed central necrosis and haemorrhage with a sinus opening into the jejunal lumen. Histological examination of this jejunal tumour showed epithelioid and spindle shaped cells. A smaller biopsied tumour was a pure spindle cell lesion. Both lesions fitted the criteria for benign stromal cell tumours. Although skenoid fibres were identified, the immunophenotype was characteristically heterogeneous. Multiple benign small intestinal tumours can raise the spectre of metastases when seen at surgery, although their presence in this case does not seem to indicate this.
Gall
J A
JA
Department of Anatomical Pathology, Royal Melbourne Hospital, Australia.
Chetty
R
R
Kemp
A J
AJ
Penfold
J C
JC
D000368:Aged; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000473:pathology*; D007580:Jejunal Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology