title: Parvalbumin as an anatomical marker for discrete subregions of the ambiguus complex in the rat.
abstract: The topography of parvalbumin-immunoreactive neurons within the ventrolateral medulla of rats was investigated. Parvalbumin is a member of the 'EF-hand' family of Ca-binding proteins and is present in certain cell types within the central nervous system (fast-firing neurons with high metabolic rates). Parvalbumin-immunoreactive neurons were located in discrete rostrocaudal divisions of the ambiguus complex corresponding to regions containing respiratory-related neurons. Based on the location of physiologically characterized respiratory-related neurons reported in the literature, parvalbumin immunoreactivity does not appear to distinguish inspiratory- from expiratory-related neurons.
authors.affiliation: Department of Pathology, University of Sydney, NSW, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Cox
authors.forename: G M
authors.initials: GM
authors.lastname: Halliday
mesh_terms: D000818:Animals; D015415:Biomarkers; D007150:Immunohistochemistry; D008297:Male; D008526:Medulla Oblongata / Q000033:anatomy & histology* / Q000166:cytology / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D010320:Parvalbumins / Q000276:immunology / Q000378:metabolism*; D051381:Rats; D011920:Rats, Inbred WF
chemical_list: D015415:Biomarkers; D010320:Parvalbumins