Sclerosing cholangitis associated with Crohn's disease and autoimmune haemolytic anaemia.
A middle-aged man was found to have autoimmune haemolytic anaemia. Seven years after the first manifestations of the anaemia, he developed jaundice without haemolysis and a diagnosis of primary sclerosing cholangitis was made by endoscopic retrograde cholangiography. Crohn's colitis was later confirmed by X-rays and colonoscopy. This association is unique to the best of our knowledge and suggests that genetic and immunological mechanisms may be involved in the pathogenesis of these diseases.
Eilam
O
O
Department of Gastroenterology, Hadassah University Hospital, Jerusalem, Israel.
Goldin
E
E
Shouval
D
D
Gimon
T
T
Brautbar
C
C
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015209:Cholangitis, Sclerosing / Q000150:complications* / Q000000981:diagnostic imaging; D003424:Crohn Disease / Q000150:complications*; D006801:Humans; D008297:Male