title: Bacterial adherence to hydrophilic polymer-coated polyurethane stents.
abstract: Biliary stent blockage by adherence of bacteria and formation of biofilm is a major problem in endoscopic stenting procedures. We have investigated bacterial adherence to hydrophilic polymer (Hydromer)-coated polyurethane stents in stationary and perfusion experiments. Adherence of gram negative and gram positive organisms under stationary conditions was similar between Hydromer-coated and non-coated control polyurethane stents; however, a marked 1 to 3 log reduction in adherence to Hydromer-coated stents occurred when perfusion experiments in phosphate buffer solution or bile were performed. The results suggest that Hydromer-coated polyurethane stents could be useful in preventing complications caused by biliary stent blockage.
authors.affiliation: Institute of Medical Microbiology and Hygiene, University of Cologne, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Jansen
authors.forename: L P
authors.initials: LP
authors.lastname: Goodman
authors.forename: D
authors.initials: D
authors.lastname: Ruiten
mesh_terms: D001422:Bacterial Adhesion / Q000502:physiology*; D013293:Enterococcus faecalis / Q000502:physiology; D004926:Escherichia coli / Q000502:physiology; D006801:Humans; D017953:Isocyanates; D007709:Klebsiella / Q000502:physiology; D011140:Polyurethanes; D011205:Povidone / Q000031:analogs & derivatives*; D011513:Proteus mirabilis / Q000502:physiology; D015607:Stents / Q000009:adverse effects
chemical_list: D017953:Isocyanates; D011140:Polyurethanes; C050067:hydromer; D011205:Povidone