title: [Serum soluble CD23 and soluble CD25 in bronchial asthmatic patients].
abstract: Serum sCD23 and sCD25 levels in asthmatic patients and healthy subjects were assayed. Serum sCD23 levels in asthmatic patients were significantly higher than those in healthy subjects (p < 0.05). Serum sCD25 levels in asthmatic patients were also significantly higher than those in healthy subjects (p < 0.02). There was a significant correlation between serum sCD23 and sCD25 levels in asthmatic patients (r = 0.52, p < 0.001). It is well known that sCD23 and sCD25 levels are regulated by different cytokines, and this study suggests that T cells play important roles in the pathogenesis of asthma.
authors.affiliation: Department of Clinical Research, Kure Kyousai Hospital, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shiota
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Ono
authors.forename: M
authors.initials: M
authors.lastname: Kaji
mesh_terms: D000328:Adult; D000368:Aged; D001249:Asthma / Q000097:blood / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017455:Receptors, IgE / Q000032:analysis*; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D012995:Solubility
chemical_list: D017455:Receptors, IgE; D015375:Receptors, Interleukin-2