Sydnone derivatives: synthesis and antimicrobial activity.
Amongst a number of mesoionic compounds studied so far, sydnones have attained importance due not only to their structural features and chemical properties, but also to their biological properties. Sydnone derivatives have been extensively studied for their biological activities, the antimicrobial activity of substituted aryl sydnones has been reported. Aryl sydnones are less toxic and more active than alkyl sydnones. Also chalcone analogues are known to have antimicrobial activity.
Pilli
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Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Safak
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C
Abbasoğlu
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U
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002175:Candida / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013558:Sydnones / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D013558:Sydnones