title: Asthma related to occupational and ambient air pollutants in nonsmokers.
abstract: We attempted to determine the association between occupational and air pollutant exposure with the development of adult asthma through the analysis of a standardized respiratory questionnaire administered to a cohort of 3914 nonsmoking adults in 1977 and again in 1987. Ambient air pollution concentrations were estimated over a 20-year period using monthly interpolations from fixed-site monitoring stations applied to zip code locations by month of residence and work site. Second-hand smoke exposure was significantly associated with the development of asthma (related risk [RR] = 1.45, confidence interval [CI] = 1.21 to 1.75). Airways obstructive disease before age 16 was related to a marked increased risk (RR = 4.24, CI = 4.03 to 4.45). An increased risk of asthma was significantly associated with increased ambient concentrations of ozone exposure in men (RR = 3.12, CI = 1.61 to 5.85).
authors.affiliation: Department of Preventive Medicine, School of Public Health, Loma Linda University, California 92350.
authors.forename: J R
authors.initials: JR
authors.lastname: Greer
authors.forename: D E
authors.initials: DE
authors.lastname: Abbey
authors.forename: R J
authors.initials: RJ
authors.lastname: Burchette
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000393:Air Pollutants / Q000009:adverse effects*; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000485:Allergens / Q000009:adverse effects; D001249:Asthma / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D002140:California / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D016273:Occupational Exposure / Q000009:adverse effects*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D014028:Tobacco Smoke Pollution / Q000009:adverse effects
chemical_list: D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D000485:Allergens; D014028:Tobacco Smoke Pollution