Translocation (Y;1)(q12;q21) in acute leukemia.
This report documents one patient with myelodysplasia evolving into acute leukemia who showed a t(Y;1) translocation confirmed by in situ hybridization. Most of the q arm of the Y chromosome was translocated to an additional q arm of chromosome 1, resulting in trisomy 1q. To our knowledge only four other cases with this t(Y;1) have been reported.
Singh
S
S
Kanematsu Research Laboratories, Royal Prince Alfred Hospital, Camperdown, Australia.
Wass
J
J
Devaraj
J
J
Young
G
G
Vincent
P
P
D000328:Adult; D002878:Chromosomes, Human, Pair 1; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic; D014998:Y Chromosome