title: Effects of high frequency stimulation on cardiac tissue with an inexcitable obstacle.
abstract: We study numerically the effects of high-frequency stimulation in excitable cardiac tissue with an inexcitable obstacle using a Fitz-Hugh Nagumo type model. We show that if the frequency of stimulation is sufficiently high and the size of the inexcitable obstacle is sufficiently large, then a re-entrant pattern can be initiated. We also show that with overdrive stimulation a re-entrant pattern can be removed provided there are no obstacles at which new re-entrant patterns are created.
authors.affiliation: Utrecht University, The Netherlands.
authors.forename: A V
authors.initials: AV
authors.lastname: Panfilov
authors.forename: J P
authors.initials: JP
authors.lastname: Keener
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D004594:Electrophysiology; D006321:Heart / Q000502:physiology*; D006801:Humans; D008433:Mathematics; D008955:Models, Cardiovascular