Successful treatment of spinal sarcoidosis by high-dose intravenous methylprednisolone.
A man with known pulmonary sarcoidosis presented with paraplegia and a rod-shaped increase in T2 signal intensity in his cervical and upper thoracic spine. Initial treatment efforts using oral doses of 40 mg of methyl-prednisolone were futile, but intravenous bolus therapy (500 mg of methyl-prednisolone daily for 1 week) led to long-lasting improvement of his neurological status and to normalization of MRI findings.
Soucek
D
D
Department of Neurology, University Hospital, Innsbruck, Austria.
Prior
C
C
Luef
G
G
Birbamer
G
G
Bauer
G
G
D000328:Adult; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D012507:Sarcoidosis / Q000188:drug therapy*; D013122:Spinal Diseases / Q000188:drug therapy*
D008775:Methylprednisolone