title: ADP-ribosylation of rainbow trout (Oncorhynchus mykiss) actin by botulinum C2 toxin.
abstract: Intracellular actin of rainbow trout macrophages was ADP-ribosylated by botulinum C2 toxin, which is composed of two nonlinked protein components, component I and trypsinized component II. The actin in the supernatants of various tissue homogenates of the trout was also directly ADP-ribosylated by component I of C2 toxin, indicating that fish actin other than those of land vertebrates is susceptible to enzymatic modification by component I of C2 toxin.
authors.affiliation: Department of Veterinary Science, College of Agriculture, University of Osaka Prefecture, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kodama
authors.forename: I
authors.initials: I
authors.lastname: Ohishi
mesh_terms: D000199:Actins / Q000187:drug effects* / Q000378:metabolism*; D000246:Adenosine Diphosphate Ribose / Q000378:metabolism*; D000818:Animals; D005075:Biological Evolution; D001905:Botulinum Toxins / Q000737:chemistry / Q000633:toxicity*; D066298:In Vitro Techniques; D007424:Intracellular Fluid / Q000187:drug effects / Q000378:metabolism; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism; D017686:Oncorhynchus mykiss / Q000378:metabolism*; D013045:Species Specificity
chemical_list: D000199:Actins; D000246:Adenosine Diphosphate Ribose; D001905:Botulinum Toxins