title: Efficacy evaluations on five chlorhexidine teat dip formulations.
abstract: Three developmental postmilking teat dip formulations containing chlorhexidine digluconate were evaluated against Staphylococcus aureus and Streptococcus agalactiae in sequential experimental exposure trials. Two additional commercial chlorhexidine digluconate teat dip products were evaluated in natural exposure trials. Under conditions of experimental challenge, the developmental formulations were efficacious against Staph. aureus but did not significantly reduce incidence of new IMI by Strep. agalactiae. None of the three formulations of a conventional germicide used as teat sanitizers effectively reduced incidence of new Strep. agalactiae IMI under experimental challenge conditions. In the natural exposure trials with negative controls, a .35% chlorhexidine teat sanitizer had efficacy of 88.7% against Staph. aureus and 51.4% against Strep. agalactiae. The .5% chlorhexidine product reduced Staph. aureus and Strep. agalactiae IMI by 86 and 56%, respectively.
authors.affiliation: Department of Animal and Food Sciences, University of Vermont, Burlington 05405.
authors.forename: P A
authors.initials: PA
authors.lastname: Drechsler
authors.forename: J K
authors.initials: JK
authors.lastname: O'Neil
authors.forename: P A
authors.initials: PA
authors.lastname: Murdough
authors.forename: A R
authors.initials: AR
authors.lastname: Lafayette
authors.forename: E E
authors.initials: EE
authors.lastname: Wildman
authors.forename: J W
authors.initials: JW
authors.lastname: Pankey
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D002417:Cattle; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D008321:Mammary Glands, Animal; D008414:Mastitis, Bovine / Q000517:prevention & control*; D013203:Staphylococcal Infections / Q000517:prevention & control; D013290:Streptococcal Infections / Q000517:prevention & control; D013292:Streptococcus agalactiae
chemical_list: D002710:Chlorhexidine