Multiple central giant cell lesions with a Noonan-like phenotype.
A small number of patients with the phenotypic features of Noonan syndrome have also developed giant cell lesions of the jaws similar to those seen in cherubism. This case report describes an individual with the features of the recently described Noonan-like/multiple giant cell lesion syndrome. Previously reported cases and issues relative to diagnosis and management are considered.
Betts
N J
NJ
Department of Oral and Maxillofacial Surgery, University of Pennsylvania School of Dental Medicine, Philadelphia.
Stewart
J C
JC
Fonseca
R J
RJ
Scott
R F
RF
D000293:Adolescent; D002636:Cherubism / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007571:Jaw Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D009634:Noonan Syndrome / Q000150:complications* / Q000473:pathology; D010641:Phenotype