Relapse of herpes simplex encephalitis after acyclovir therapy.
A case of herpes simplex encephalitis in a previously healthy 17-month-old girl relapsing 1 week after completion of a 10-day acyclovir therapy is described. The child responded favourably to a second 10-day course with acyclovir. The time of relapse and the satisfactory response to a second course of acyclovir treatment indicate that the first course of therapy was inadequate for eradication of herpes simplex virus infection.
Nicolaidou
P
P
First Department of Paediatrics, University of Athens, St. Sophie, Children's Hospital, Greece.
Iacovidou
N
N
Youroukos
S
S
Liacopoulou-Tsitsipi
T
T
Kattamis
C
C
D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004660:Encephalitis / Q000188:drug therapy*; D005260:Female; D006561:Herpes Simplex / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D012008:Recurrence
D000212:Acyclovir