title: "BFA bodies": a subcompartment of the endoplasmic reticulum.
abstract: A specialized region of the endoplasmic reticulum--the BFA body--is defined by the site of accumulation of coatomer when nonclathrin coat protein (COP)-coated vesicle assembly is prevented by the drug brefeldin A (BFA). BFA bodies are formed by part smooth, part rough domains of endoplasmic reticulum that are cis to the classical transitional endoplasmic reticulum and to BFA-induced Golgi remnants.
authors.affiliation: Department of Morphology, University of Geneva Medical School, Switzerland.
authors.forename: L
authors.initials: L
authors.lastname: Orci
authors.forename: A
authors.initials: A
authors.lastname: Perrelet
authors.forename: M
authors.initials: M
authors.lastname: Ravazzola
authors.forename: F T
authors.initials: FT
authors.lastname: Wieland
authors.forename: R
authors.initials: R
authors.lastname: Schekman
authors.forename: J E
authors.initials: JE
authors.lastname: Rothman
mesh_terms: D000818:Animals; D020126:Brefeldin A; D020756:Coatomer Protein; D003517:Cyclopentanes / Q000494:pharmacology*; D004721:Endoplasmic Reticulum / Q000648:ultrastructure*; D006056:Golgi Apparatus / Q000648:ultrastructure; D007150:Immunohistochemistry; D007425:Intracellular Membranes / Q000648:ultrastructure; D007515:Islets of Langerhans / Q000648:ultrastructure; D008565:Membrane Proteins / Q000378:metabolism; D008854:Microscopy, Electron; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D051381:Rats
chemical_list: D020756:Coatomer Protein; D003517:Cyclopentanes; D008565:Membrane Proteins; D008869:Microtubule-Associated Proteins; D020126:Brefeldin A