Zinc counteracts experimentally-induced cirrhotic changes in rats.
In the present study, cirrhosis was induced in rats by administration of carbon tetra chloride for 8 weeks. In these animals ZnSo4 (equivalent to 100 and 200 micrograms of zinc) was administered orally and liver function tests and plasma zinc (Zn) estimations were carried out after 2 and 4 week intervals. The results revealed that Zn supplement counteracts cirrhotic changes in liver.
Vanaja
R
R
Institute of Physiology and Experimental Medicine, Madras Medical College.
Gajalakshmi
B S
BS
D000818:Animals; D002251:Carbon Tetrachloride / Q000037:antagonists & inhibitors; D008106:Liver Cirrhosis, Experimental / Q000139:chemically induced / Q000517:prevention & control*; D008111:Liver Function Tests; D008297:Male; D051381:Rats; D015032:Zinc / Q000097:blood / Q000494:pharmacology*
D002251:Carbon Tetrachloride; D015032:Zinc