[Primary report of a specific light absorption peak of red blood cells in pregnancy induced hypertension--one drop blood assay with photoacoustic spectroscopy].
One drop of red blood cells (RBC) was assayed with double beam photoacoustic spectroscopy device (PAS) in 89 blood samples collected from 71 pregnant women during 3rd trimester of pregnancy. A specific light absorption peak at a spectral range of 620-650 nm was showed in 86.36% of women with pregnancy induced hypertension (PIH), while only 16.67% of normal pregnant women (P < 0.01). However we can not identify the component which induced this specific peak in RBC. Our conclusion is that this simple assay could be used promisingly in prediction and differential diagnosis for PIH in clinic.
Fu
Y L
YL
Guangzhou Maternal and Neonatal Hospital.
D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D013057:Spectrum Analysis
D006454:Hemoglobins