Beneficial liaisons: radiobiology meets cellular and molecular biology.
The scientific knowledge that is emerging in all fields of medicine is rapidly changing our understanding of the concepts in radiation oncology. In this review, some of the classic radiation biology theories and models are examined and newer 'models' are illustrated. The ability of radiation oncologists to remain current with the newer scientific findings is essential to the development of improved therapeutic strategies and, importantly, to the proper balance between investment in technology and biology.
Coleman
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CN
Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA 02115.
D002453:Cell Cycle / Q000528:radiation effects; D005786:Gene Expression Regulation / Q000528:radiation effects; D006801:Humans; D008967:Molecular Biology; D009369:Neoplasms / Q000532:radiotherapy*; D011853:Radiobiology; D015398:Signal Transduction / Q000528:radiation effects; D009626:Terminology as Topic