title: Changes of soft-tissue water examined with magnetic resonance and electrical impedance tomography: an in vivo experiment.
abstract: The purpose of this study was the examination of short-term changes in soft-tissue water under in vivo conditions. In 12 healthy volunteers the water distribution of a selected slice of the lower limb was examined after change of position and rapid infusion of 0.9% saline solution. Two methods were used for data acquisition: magnetic resonance imaging (MRI) (Repetition Time (TR) = 1600 msec, Inversion Time (TI) = 300 msec, Echo Time (TE) = 22 msec) and electrical impedance tomography (EIT). In orthostatic equilibrium all 12 volunteers demonstrated changes of MR signal intensity and resistivity in the range of 12% and 7%, respectively. After infusion, mean changes of signal intensity and resistivity were 7% and 4%, respectively. The overall correlation of MRI and EIT was -0.96 (p < 0.001). Results indicate that inversion recovery sequences are a sensitive method of detecting in vivo changes of water distribution in selected areas of the body.
authors.affiliation: Department of Radiology, University of Essen, Germany.
authors.forename: K W
authors.initials: KW
authors.lastname: Sievers
authors.forename: J
authors.initials: J
authors.lastname: Gauger
authors.forename: T
authors.initials: T
authors.lastname: Bauermann
authors.forename: E
authors.initials: E
authors.lastname: Löhr
mesh_terms: D000328:Adult; D001834:Body Water / Q000502:physiology*; D017097:Electric Impedance; D006801:Humans; D007262:Infusions, Intravenous; D007866:Leg / Q000502:physiology; D008279:Magnetic Resonance Imaging; D008297:Male; D011187:Posture / Q000502:physiology*; D012965:Sodium Chloride / Q000008:administration & dosage; D014054:Tomography / Q000379:methods
chemical_list: D012965:Sodium Chloride