Abnormalities of the interdigestive migrating motor complex in a patient with carcinoid syndrome.
Intraluminal pressures of the gastric antrum, duodenum and jejunum were recorded for 206 min after a 12 h fast in a patient with carcinoid syndrome due to neoplasia of enterochromaffin cells of the ileum and with hepatic metastases. The most conspicuous alteration was a tachyrrhythmia of 16 waves/min predominating in the activity fronts of both duodenum and jejunum. Periods of 11-12 waves/min frequency appeared irregularly and the simultaneous occurrence of frequencies of 11 waves/min and 16 waves/min was also recorded. The gastric antrum was fully quiescent throughout the study. The alterations observed are presumed to be produced by substances secreted by the carcinoid tumor.
Meneghelli
U G
UG
Hospital das Clínicas, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
Martinelli
A L
AL
de Oliveira
R B
RB
Villanova
M G
MG
Dantas
R O
RO
Soares
F A
FA
D004386:Duodenum / Q000503:physiopathology; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000503:physiopathology*; D007583:Jejunum / Q000503:physiopathology; D008113:Liver Neoplasms / Q000503:physiopathology / Q000556:secondary*; D008303:Malignant Carcinoid Syndrome / Q000503:physiopathology*; D008365:Manometry; D008875:Middle Aged; D016065:Myoelectric Complex, Migrating / Q000502:physiology*; D013270:Stomach / Q000503:physiopathology; D013610:Tachycardia