Two computer programs using logit transformation for the analysis of S-shaped curves.
Two BASIC computer programs using logit transformation for the analysis of S-shaped curves are presented. The first program estimates the median effective dose (ED50) of drugs. A maximum likelihood method similar to Finney's algorithm of probit analysis is applied. The second fits S-shaped curves to empirical data which cannot be transformed easily to proportions. Logit transformation proves to be a simple and accurate alternative to probit transformation when computing memory is limited or calculation speed is critical.
Rieger
E
E
Department of Dermatology, University of Graz, Austria.
Bijl
J J
JJ
Rieger
M
M
D000465:Algorithms; D003199:Computer Systems; D003627:Data Interpretation, Statistical; D004305:Dose-Response Relationship, Drug; D016015:Logistic Models; D004364:Pharmaceutical Preparations / Q000008:administration & dosage; D012984:Software; D012985:Software Design
D004364:Pharmaceutical Preparations