title: Ketorolac as a rapid and effective treatment of migraine headache: evaluations by patients.
abstract: The objective of this study was to determine the speed and efficiency of ketorolac in reducing the symptoms of migraine headache. Twenty-three patients who presented in the emergency department during the period between April and July 1992 with a previous diagnosis of migraine headache were considered for the study. Patients subjectively evaluated parameters of their migraine headaches (eg, pain and nausea) with a numerical scale and were asked to re-evaluate these same parameters at 30, 60, and 360 minutes after a single injection of Ketorolac. Seventeen (74%) patients reported a decrease in headache symptoms that was significant (P < .005) after 1 hour. Relief lasted at least 6 hours after injection.
authors.affiliation: Department of Surgery (Emergency Services), University of Texas Medical Branch, Galveston 77555.
authors.forename: C P
authors.initials: CP
authors.lastname: Davis
authors.forename: P R
authors.initials: PR
authors.lastname: Torre
authors.forename: N C
authors.initials: NC
authors.lastname: Schafer
authors.forename: B
authors.initials: B
authors.lastname: Dave
authors.forename: B
authors.initials: B
authors.lastname: Bass
mesh_terms: D000208:Acute Disease; D000328:Adult; D000700:Analgesics / Q000494:pharmacology / Q000627:therapeutic use*; D001835:Body Weight; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D020910:Ketorolac; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D010147:Pain Measurement; D017060:Patient Satisfaction; D012720:Severity of Illness Index; D013997:Time Factors; D014046:Tolmetin / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D014046:Tolmetin; D020910:Ketorolac