title: [The hierarchy of complexes and compact structures of trivaline with nucleic acids. I. Interaction of trivaline with double-stranded DNA].
abstract: It was shown that trivaline-poly(U) complexes have no appreciable fluorescence at any peptide concentration if the polymer concentration is less than critical. By electron microscopy it was shown that dsDNA molecules undergo a second step of compactization if polymer and peptide concentrations are high enough. The diameter of this rod-like particles is over 40 nm. If the polymer concentration is less than critical, dsDNA molecules form with trivaline extended structures of dissimilar morphology. We propose a scheme of trivaline-dsDNA complexes and compact structure formation, beginning from a dimer complex. It is consistent with the results of equilibrium dialysis, fluorescence, electron microscopy, flow linear and circular dichroism measurements.
authors.forename: S A
authors.initials: SA
authors.lastname: Strel'tsov
authors.forename: T E
authors.initials: TE
authors.lastname: Semenov
authors.forename: O V
authors.initials: OV
authors.lastname: Moroz
mesh_terms: D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure; D005453:Fluorescence; D008854:Microscopy, Electron; D011072:Poly U / Q000737:chemistry*; D011487:Protein Conformation; D014633:Valine / Q000737:chemistry*
chemical_list: D011072:Poly U; D004247:DNA; D014633:Valine
vernacular_title: Ob ierarkhii kompleksov i kompaktnykh struktur trivalina s nukleinovymi kislotami. I. Vzaimodeĭstvie trivalina s dtsDNK.