SPECT, CT and MRI in a Turkish family with Huntington's disease.
A Turkish family with Huntington's disease documented on CT, MRI and SPECT is reported. Whereas in clinically definite cases CT and MRI are of limited value and SPECT does not add anything of value, in one asymptomatic subject SPECT showed moderate caudate nucleus hypoperfusion, underlining the hypothesis that SPECT may have a role in predicting Huntington's disease.
Bruyn
R P
RP
Department of Neurology, Medisch Spectrum Twente, Enschede, The Netherlands.
Hageman
G
G
Geelen
J A
JA
van der Weel
F A
FA
Rozeboom
A R
AR
Barkhof
F
F
Scheltens
P
P
D000328:Adult; D001284:Atrophy; D001921:Brain / Q000098:blood supply / Q000473:pathology*; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis / Q000235:genetics*; D008279:Magnetic Resonance Imaging; D008297:Male; D010375:Pedigree; D012039:Regional Blood Flow / Q000502:physiology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed