title: Inhibition of formalin-induced responses of spinal dorsal horn neurons by stimulation of lateral reticular nucleus in rats.
abstract: The effects of stimulation of the lateral reticular nucleus (LRN) on responses of spinal dorsal horn neurons produced by formalin (5%, 50 microliters, sc) were investigated. In 12 out of 19 neurons tested, formalin induced 2 distinct phases of response. The first phase was initiated immediately after the injection of formalin and lasted for 3-8 min. The second phase started gradually 20-35 min after administration of formalin and lasted 30-65 min. Both phases of the response were inhibited by LRN stimulation.
authors.affiliation: Shanghai Brain Research Institute, Chinese Academy of Sciences.
authors.forename: G Z
authors.initials: GZ
authors.lastname: Zhao
authors.forename: R Y
authors.initials: RY
authors.lastname: Liu
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Zhao
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D005557:Formaldehyde / Q000494:pharmacology*; D009474:Neurons / Q000502:physiology; D009619:Nociceptors / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D012154:Reticular Formation / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*
chemical_list: D005557:Formaldehyde