title: Naftidrofuryl treatment for rest cramp.
abstract: A double-blind placebo-controlled study was carried out in 14 subjects to investigate the effect of naftidrofuryl in the treatment of rest cramp. Naftidrofuryl caused a significant reduction in cramp frequency (median naftidrofuryl = 5; median placebo = 17; P < 0.004) and a significant 34% increase in cramp free days (median naftidrofuryl = 22; median placebo = 14; P < 0.004). Naftidrofuryl is an effective alternative to quinine in the treatment of this painful condition.
authors.affiliation: St Luke's Hospital, Bradford, UK.
authors.forename: J B
authors.initials: JB
authors.lastname: Young
authors.forename: M J
authors.initials: MJ
authors.lastname: Connolly
mesh_terms: D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009120:Muscle Cramp / Q000517:prevention & control*; D009257:Nafronyl / Q000627:therapeutic use*; D012146:Rest; D013997:Time Factors
chemical_list: D009257:Nafronyl