title: Clear cell basal cell carcinoma: an unusual degenerative variant.
abstract: Clear cell basal cell carcinoma (BCC) is an unusual variant of BCC which is characterized by a variable component of large clear cells. Twenty cases are presented which are further subdivided into pure, mixed, or metatypical categories. Although initially thought to represent sebaceous or tricholemmal differentiation, electron microscopic studies demonstrated that the clear cell changes are a degenerative phenomenon, probably involving lysosomes.
authors.affiliation: Department of Dermatology, University of California, Irvine, Orange 92668.
authors.forename: R J
authors.initials: RJ
authors.lastname: Barr
authors.forename: K S
authors.initials: KS
authors.lastname: Alpern
authors.forename: D J
authors.initials: DJ
authors.lastname: Santa Cruz
authors.forename: D F
authors.initials: DF
authors.lastname: Fretzin
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000145:classification / Q000453:epidemiology / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D008247:Lysosomes / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012878:Skin Neoplasms / Q000145:classification / Q000453:epidemiology / Q000473:pathology*