title: [Susceptibility in vitro to certain quinolines of gram-negative bacteria and gram-positive cocci causing urinary tract infections].
abstract: Susceptibility to norfloxacin, ofloxacin, pipemidic acid and nalidixic acid of 848 bacterial strains isolated from urine of patients treated in 1989-1992 in Wrocław hospitals was investigated. The study, performed by the disc diffusion methods, concerned 568 Enterobacteriaceae strains, 147 Gram-negative non-fermenting bacteria and 133 strains of staphylococci. Highest percentage (90-100%) of susceptibility to all used antimicrobial agents was detected among Escherichia, Proteus, Morganella and Citrobacter. Less frequent susceptibility (30-70%) was observed among Klebsiella, Enterobacter and Serratia. Among strains of P. aeruginosa susceptible to norfloxacin and ofloxacin were, respectively, 61.4 and 22.2% isolates. Over 95% of strains of P. aeruginosa were resistant to nalidixic acid. Among other non-fermenting Gram-negative bacteria, over 50% were resistant to norfloxacin and ofloxacin. Both S. aureus and S. epidermidis were susceptible to ofloxacin and norfloxacin in 81-93% of tested strains. They were 2-3 times less frequently susceptible to pipemidic and nalidixic acid.
authors.affiliation: Katedra i Zakład Mikrobiologii, Katedra i Klinika Nefrologii, Wrocławiu.
authors.forename: E
authors.initials: E
authors.lastname: Mróz
authors.forename: S
authors.initials: S
authors.lastname: Jankowski
authors.forename: J
authors.initials: J
authors.lastname: Bartelmus
authors.forename: K
authors.initials: K
authors.lastname: Grzybek-Hryncewicz
authors.forename: J
authors.initials: J
authors.lastname: Ruczkowska
authors.forename: J
authors.initials: J
authors.lastname: Starek
authors.forename: M
authors.initials: M
authors.lastname: Boratyńska
mesh_terms: D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects / Q000302:isolation & purification; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D013045:Species Specificity; D013210:Staphylococcus / Q000187:drug effects* / Q000302:isolation & purification; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D014556:Urine / Q000382:microbiology
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents
vernacular_title: Wrazliwość in vitro na niektóre chinolony Gram-ujemnych pałeczek i Gram-dodatnich ziarenkowców powodujacych zakazenia układu moczowego.