Second messengers in neuronal signaling.
The past decade has witnessed an enormous increase in our knowledge of the variety and complexity of intracellular signaling events that follow receptor binding on the cell surface. This overview emphasizes the phosphoinositidase C-mediated dual messenger pathway in brain and in brain-derived cells, with special reference to possible significance for research on the dementias.
Agranoff
B W
BW
Mental Health Research Institute, University of Michigan, Ann Arbor 48104-1687.
D000818:Animals; D001921:Brain / Q000502:physiology*; D003704:Dementia / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D009474:Neurons / Q000502:physiology*; D010716:Phosphatidylinositols / Q000378:metabolism; D015290:Second Messenger Systems; D015398:Signal Transduction / Q000502:physiology*
D010716:Phosphatidylinositols