title: Elevated estrogen 16 alpha-hydroxylase activity: is this a genotoxic or nongenotoxic biomarker in human breast cancer risk?
authors.affiliation: Department of Environmental Health, University of Cincinnati Medical Center, OH 45267-0056.
authors.forename: D W
authors.initials: DW
authors.lastname: Nebert
mesh_terms: D001189:Aryl Hydrocarbon Hydroxylases; D014408:Biomarkers, Tumor / Q000378:metabolism; D001943:Breast Neoplasms / Q000201:enzymology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism; D005260:Female; D006801:Humans; D010084:Oxidation-Reduction; D011110:Polymorphism, Genetic / Q000502:physiology; D011960:Receptors, Estrogen / Q000378:metabolism; D012307:Risk Factors; D039181:Steroid 16-alpha-Hydroxylase; D013250:Steroid Hydroxylases / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D011960:Receptors, Estrogen; D004958:Estradiol; D003577:Cytochrome P-450 Enzyme System; D013250:Steroid Hydroxylases; D001189:Aryl Hydrocarbon Hydroxylases; D039181:Steroid 16-alpha-Hydroxylase