title: [Clinical, diagnostic and therapeutic aspects of Moraxella catarrhalis infections].
abstract: Moraxella catarrhalis is a Gram-negative diplococcus of the Neisseriaceae family now recognized as a cause of acute otitis media in pediatric patients and of lower respiratory tract infections in debilitated adults. The finding that 80% to 90% of strains produce beta-lactamases together with reports of cases of bacteremia and arthritis due to M. catarrhalis suggest an increasing pathogenic role for this organism. Antibiotic susceptibility testing suggests that the greatest bactericidal effect is provided by amoxicillin-clavulanic acid.
authors.affiliation: Laboratoire de Microbiologie, Hôpital Robert-Debré, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Bourgeois
authors.forename: N
authors.initials: N
authors.lastname: Lambert-Zechovsky
authors.forename: E
authors.initials: E
authors.lastname: Bingen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002462:Cell Membrane / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000494:pharmacology; D003937:Diagnosis, Differential; D004352:Drug Resistance, Microbial; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D001936:Moraxella catarrhalis / Q000187:drug effects / Q000302:isolation & purification* / Q000472:pathogenicity / Q000648:ultrastructure; D016870:Neisseriaceae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology*; D010033:Otitis Media / Q000382:microbiology*; D010405:Penicillinase; D012141:Respiratory Tract Infections / Q000382:microbiology*; D014774:Virulence
chemical_list: D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D019818:Clavulanic Acid; D010405:Penicillinase
vernacular_title: Aspects cliniques, diagnostiques et thérapeutiques des infections à Moraxella catarrhalis.