Overview of clinical trials in congestive heart failure.
Heart failure is the only cardiovascular disorder which is increasingly prevalent in North America. Several large clinical trials have emerged within the past 10 years. The results from some of these trials have had a significant impact on the way congestive heart failure is recognized and treated. The objective of this review is not to review exhaustively all recent clinical trials in heart failure but to present the most important ones selected because of their impact on how one understands and treats congestive heart failure in 1993. The results, as well as some important pathophysiological considerations related to these trials, will be addressed.
White
M
M
Department of Medicine, Montreal Heart Institute, Quebec.
Rouleau
J L
JL
D002986:Clinical Trials as Topic; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D016277:Ventricular Function, Left / Q000502:physiology