title: Variation of cortical hypertrophy depending on the medullary filling material. An experimental study of canine tibial diaphysis.
abstract: In order to evaluate the mineralization of bone after polymethyl methacrylate cementation, measurements of the periosteal apposition were made histologically and measurements of the bone-mineral content were made by dual-photon absorptiometry of the tibial diaphysis in 15 adult mongrel dogs in paired studies. Six dogs were investigated 4 weeks after intramedullary reaming of both sides and obturation of the medullary cavity with bone-wax on one side. Nine dogs were reamed on both sides. The medullary cavities were filled with polymethyl methacrylate bone-cement and bone-wax, respectively. The authors found (1) an increased bone-mineral content and an increased periosteal apposition after filling with bone-wax in comparison with the reamed side and (2) a decreased bone-mineral content and a decreased periosteal apposition on the cemented side in comparison with bone-wax. These findings are interpreted as consequential upon repair processes with a high remodeling and mineralization rate after reaming or filling with bone-wax, whereas remodeling in inhibited after filling with acrylic bone-cement.
authors.affiliation: Department of Orthopedic Surgery, Rigshospitalet, University of Copenhagen, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Kramhøft
authors.forename: S
authors.initials: S
authors.lastname: Bødtker
authors.forename: L
authors.initials: L
authors.lastname: Nimb
authors.forename: J S
authors.initials: JS
authors.lastname: Jensen
mesh_terms: D015502:Absorptiometry, Photon; D000818:Animals; D015519:Bone Density / Q000502:physiology; D016723:Bone Remodeling / Q000502:physiology; D004285:Dogs; D004338:Drug Combinations; D006984:Hypertrophy; D008768:Methylmethacrylates; D010168:Palmitates; D013977:Tibia / Q000502:physiology* / Q000601:surgery; D014885:Waxes
chemical_list: D004338:Drug Combinations; D008768:Methylmethacrylates; D010168:Palmitates; D014885:Waxes; C055480:bone wax