Clinicopathological studies of multiple cancers in the large bowel and other organs.
During the past 17 years, 1,463 cases of cancer of large intestine, there were 117 cases (8.0%) with overlapping cancer in other organs. The male/female ratio was 1.0:1.1 and the mean age was 65.8 years old. The region of existence in other organs was in the order of frequency: stomach 28.3%, uterus 26.3%, and liver 8.1%. The location and histology showed almost similar results to that of single cancer. In comparison with single cancer, overlapping cancer cases showed a high complication rate of adenoma. So it was suggested that a region of cancer development was present but latent. The preceding cases of cancer of the uterus almost all underwent radiotherapy. About 36% of their histology of colon cancer were mucinous carcinoma suggesting at least the development of cancer by radiation.
Akagi
Y
Y
Department of Surgery, Kurume University School of Medicine, Japan.
Araki
Y
Y
Ogata
Y
Y
Morodomi
T
T
Shirouzu
K
K
Isomoto
H
H
Kakegawa
T
T
D000367:Age Factors; D000368:Aged; D003110:Colonic Neoplasms / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D011878:Radiotherapy / Q000009:adverse effects; D012737:Sex Factors; D016896:Treatment Outcome