Monoamine oxidase inhibitors and anesthesia: an updated literature review.
Safe anesthesia for patients taking MAOIs has been possible since the 1980s using judicious choice of agents. The introduction of a new class of MAOIs (RIMA) has increased the margin of safety for these anesthetics. These drugs allow selective and rapidly reversible inhibition of type A-MAO. The pharmacologic effects of this new class of drug as well as their potential interactions with agents used in anesthesia are reviewed.
Blom-Peters
L
L
Service d'Anesthésiologie, CHR de la Citadelle, Liège, Belgique.
Lamy
M
M
D000758:Anesthesia; D000777:Anesthetics / Q000494:pharmacology; D001549:Benzamides / Q000494:pharmacology; D004347:Drug Interactions; D006801:Humans; D020912:Moclobemide; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*
D000777:Anesthetics; D001549:Benzamides; D008996:Monoamine Oxidase Inhibitors; D020912:Moclobemide