Persistence of a high degree of structural organization of the telencephalon in brain homotransplants in adult Triturus carnifex (Urodele Amphibians).
Brains of adult Urodele Amphibians (Triturus carnifex Laur.) were homoplastically transplanted in conditions of complete morpho-functional isolation and fixed 100 and 365 days after the operation. Results show that in the post-telencephalic regions structural organization disappear in all cases, while, in some cases the telencephalon retain a fairly complex structural organization even after one year. The heterogeneous nature of the histological patterns observed may be attributed to the different size of the matrix areas, besides the different degree of immune response of the host to the graft. In the telencephalic district, where the matrix areas are particularly well developed, undifferentiated elements of these areas would be capable of opposing the degenerative phenomena in the transplants by neoformation of neurons. However, in post-telencephalic districts, where the matrix areas are less developed or absent, it would not be possible to make up for neuronal degeneration and these regions disappear or are formed only by some undifferentiated elements outside the surviving ependyma portions.
Margotta
V
V
Dipartimento di Biologia animale e dell'Uomo (Facoltà di Scienze), Università di Roma La Sapienza, Italy.
Filoni
S
S
Del Vecchio
P
P
D000818:Animals; D016380:Brain Tissue Transplantation; D005260:Female; D006085:Graft Survival; D008297:Male; D008938:Mitosis; D009474:Neurons / Q000166:cytology; D013687:Telencephalon / Q000033:anatomy & histology* / Q000166:cytology / Q000637:transplantation*; D013997:Time Factors; D014319:Triturus