Clinical cardiopulmonary bypass without systemic anticoagulation.
Heparin-coated perfusion systems have been used to perform cardiopulmonary bypass with decreased systemic heparin dosages. We report the case of a 60-year-old man with end-stage liver disease and severe aortic stenosis who underwent an aortic valve replacement without systemic anticoagulation, employing a heparin-coated perfusion system. In patients with a contraindication to systemic anticoagulation, cardiopulmonary bypass with a heparin-coated system without systemic anticoagulation may be a viable alternative.
Dowling
R D
RD
Department of Cardiothoracic Surgery and Anesthesiology, University of Pittsburgh, PA 15216.
Brown
M E
ME
Whittington
R O
RO
Quinlan
J J
JJ
Armitage
J M
JM
D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery*; D002315:Cardiopulmonary Bypass / Q000379:methods; D006350:Heart Valve Prosthesis / Q000379:methods; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D017093:Liver Failure / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion / Q000379:methods; D012720:Severity of Illness Index
D006493:Heparin