Principles of genetics in the molecular era. A primer for dermatologists.
Advances in technology have resulted in an explosion of information about the molecular bases of human inheritance and human disease. Much of the new terminology is daunting, and it is becoming increasingly difficult to remain current. This article briefly reviews some of the changes in our understanding of the rules of inheritance and recurrence risks for genetic disorders. Further readings are suggested, and a glossary of technical terms is provided.
Sybert
V P
VP
Department of Pediatrics, University of Washington School of Medicine, Seattle.
D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D004247:DNA / Q000235:genetics*; D016172:DNA Fingerprinting; D004261:DNA Replication / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics; D003880:Dermatology; D005260:Female; D030342:Genetic Diseases, Inborn / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D008297:Male; D008967:Molecular Biology / Q000379:methods*; D015394:Molecular Structure; D009030:Mosaicism / Q000235:genetics; D009154:Mutation; D009711:Nucleotides / Q000235:genetics; D011110:Polymorphism, Genetic / Q000235:genetics; D014176:Protein Biosynthesis; D013577:Syndrome; D014158:Transcription, Genetic
D004272:DNA, Mitochondrial; D009711:Nucleotides; D004247:DNA