[The effect of adenosine on the contractile function of the heart during experimental ischemia and reperfusion].
It has been shown that 30 min ischemia followed by 30 min reperfusion inhibits cardiac contractility. The addition of adenosine at a concentration of 50 or 100 mumol/l into the perfusate normalized a decreased cardiac contractility and prevented the onset of contracture.
Selizarova
N O
NO
Eliseev
V V
VV
D000241:Adenosine / Q000627:therapeutic use*; D000818:Animals; D005260:Female; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000628:therapy*; D015425:Myocardial Reperfusion; D051381:Rats
D000241:Adenosine
Deĭstvie adenozina na sokratitelńuiu funktsiiu serdtsa pri éksperimentalńoĭ ishemii i reperfuzii.