[Evaluation of a micromethod for the bactericidal activity of five disinfectants on 108 hospital strains].
The authors studied 5 disinfectants containing aldehyde and quaternary ammonium against 108 hospital strains. The minimal bactericidal activities (MBC) were determined with a microdilution method and the dilution-neutralization method (AFNOR T 72-150). The microdilution method results were validated using the MBCs of four reference strains tested with the dilution-neutralization method (AFNOR T 72-150). 3 disinfectants proved to be valuable. 1 disinfectant was valuable but with a MBC toward all bacteria only a dilution away from the dilution of use. 1 disinfectant was determined as unsatisfactory as 9.5 p. cent of all strains proved resistant toward it. All disinfectants matched AFNOR standards; but those specifications did not match toward hospital strains. Such an evaluation using a simple and reliable method should be of use.
Dusseau
J Y
JY
Laboratoire de Biologie Médicale, Hôpital d'Instruction des Armées Desgenettes, Lyon, France.
Chapalain
J C
JC
Rouby
Y
Y
Reverdy
M E
ME
Bartoli
M
M
D000150:Acinetobacter / Q000187:drug effects; D004202:Disinfectants / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D007709:Klebsiella / Q000187:drug effects; D011511:Proteus / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects*; D013212:Staphylococcus epidermidis / Q000187:drug effects
D004202:Disinfectants
Evaluation par une microméthode de l'activité bactéricide de cinq désinfectants sur 108 souches hospitalières.