Paraneoplastic pyoderma gangrenosum.
Pyoderma Gangrenosum (PG) is often associated with an underlying disease. PG as a paraneoplastic disease is illustrated by the presentation of four patients with malignancy of myeloproliferative origin and PG. An associated malignancy is found in approximately 7% of patients with PG, most commonly haematologic in nature and in particular leukaemia. Clinically the PG is often of the superficial bullous variant and is associated with a poor prognosis.
Duguid
C M
CM
Department of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland.
O'Loughlin
S
S
Otridge
B
B
Powell
F C
FC
D000368:Aged; D005260:Female; D006801:Humans; D007938:Leukemia / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000473:pathology*; D011087:Polycythemia Vera / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology; D017511:Pyoderma Gangrenosum / Q000473:pathology*