title: The isolation and nucleotide sequence of the pyruvate decarboxylase gene from Kluyveromyces marxianus.
abstract: We have determined the nucleotide sequence of a 2360-basepair (bp) region of the Kluyveromyces marxianus genome containing the structural gene for the enzyme pyruvate decarboxylase (PDC). Comparison of the deduced amino-acid sequence of this gene to that of the Saccharomyces cerevisiae PDC genes reveals extensive homology including a motif common to thiamin diphosphate-dependent enzymes.
authors.affiliation: Department of Microbiology, University of Guelph, Ontario, Canada.
authors.forename: P
authors.initials: P
authors.lastname: Holloway
authors.forename: R E
authors.initials: RE
authors.lastname: Subden
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D004271:DNA, Fungal; D005800:Genes, Fungal; D007716:Kluyveromyces / Q000201:enzymology / Q000235:genetics*; D008969:Molecular Sequence Data; D011767:Pyruvate Decarboxylase / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
chemical_list: D004271:DNA, Fungal; D011767:Pyruvate Decarboxylase