title: Vaginal occlusion induced by cancer therapy.
abstract: Two adolescent girls with acquired vaginal occlusion and resultant hematometracolpos are presented. Both are long-term survivors of childhood malignancies, who prior to multiagent chemotherapy and pelvic irradiation had normal uteri by imaging. Both were amenorrheic post therapy. Routine follow-up computed tomography (CT) scans to monitor their malignancies demonstrated unexpected cystic pelvic masses, subsequently diagnosed as hematometracolpos.
authors.affiliation: Department of Diagnostic Imaging, St. Jude Children's Research Hospital, University of Tennessee, Memphis 38105.
authors.forename: S C
authors.initials: SC
authors.lastname: Kaste
authors.forename: S A
authors.initials: SA
authors.lastname: Gronemeyer
authors.forename: D
authors.initials: D
authors.lastname: Muram
mesh_terms: D000293:Adolescent; D000568:Amenorrhea / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006409:Hematometra / Q000209:etiology*; D006801:Humans; D007512:Ischium; D009369:Neoplasms / Q000628:therapy*; D010388:Pelvis; D011878:Radiotherapy / Q000009:adverse effects*; D018232:Rhabdomyosarcoma, Alveolar / Q000628:therapy; D012512:Sarcoma, Ewing / Q000628:therapy; D014057:Tomography, X-Ray Computed; D014621:Vagina / Q000000981:diagnostic imaging / Q000473:pathology* / Q000528:radiation effects