title: Hepoxilins.
abstract: 1. This article reviews the formation, metabolism and pharmacological actions of the hepoxilins. These are biologically active hydroxy epoxide derivatives of arachidonic acid formed through the 12-lipoxygenase pathway. 2. This review summarizes literature data available at the time of writing of this article.
authors.affiliation: Division of Neurosciences, Hospital for Sick Children, Toronto, Canada.
authors.forename: C R
authors.initials: CR
authors.lastname: Pace-Asciak
mesh_terms: D015126:8,11,14-Eicosatrienoic Acid / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D006801:Humans
chemical_list: C022948:10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid; C038243:8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid; D015126:8,11,14-Eicosatrienoic Acid