Persistent human parvovirus B19 infection following an acute infection with meningitis in an immunocompetent patient.
A case in which parvovirus B19 infection persisted over a prolonged period of time in the blood of an immunocompetent patient following an acute infection with meningitis is reported. Using a nested polymerase chain reaction assay the viral genome was detected in cerebrospinal fluid as well as in blood at the time of overt disease and in consecutive blood samples collected for up to nine months.
Cassinotti
P
P
Institute for Clinical Microbiology and Immunology, St. Gallen, Switzerland.
Schultze
D
D
Schlageter
P
P
Chevili
S
S
Siegl
G
G
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D004279:DNA, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008587:Meningitis, Viral / Q000134:cerebrospinal fluid / Q000276:immunology / Q000382:microbiology*; D010198:Pancytopenia / Q000382:microbiology; D010322:Parvoviridae Infections / Q000134:cerebrospinal fluid / Q000276:immunology / Q000382:microbiology*; D016732:Parvovirus B19, Human / Q000276:immunology / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction
D000914:Antibodies, Viral; D004279:DNA, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M