title: Isometric exercise increases strength and does not produce sustained creatinine phosphokinase increases in a patient with polymyositis.
abstract: A patient with active stable idiopathic polymyositis received a 4-week supervised right quadriceps and biceps isometric strengthening program. He demonstrated a significant increase in isometric peak torque without a sustained rise in creatinine phosphokinase (CPK). A significant decrease in postexercise CPK occurred at the end of the exercise program. We conclude a randomized clinical trial using a nonexercised patient group vs an exercised patient group may be useful.
authors.affiliation: Department of Rehabilitation Medicine, National Institutes of Health, Bethesda, MD 20892.
authors.forename: J E
authors.initials: JE
authors.lastname: Hicks
authors.forename: F
authors.initials: F
authors.lastname: Miller
authors.forename: P
authors.initials: P
authors.lastname: Plotz
authors.forename: T H
authors.initials: TH
authors.lastname: Chen
authors.forename: L
authors.initials: L
authors.lastname: Gerber
mesh_terms: D003402:Creatine Kinase / Q000097:blood*; D005081:Exercise Therapy; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology*; D017285:Polymyositis / Q000097:blood / Q000503:physiopathology* / Q000628:therapy*
chemical_list: D003402:Creatine Kinase