title: Myasthenia gravis and scleroderma.
abstract: Myasthenia gravis is an autoimmune disease that is associated with antibodies to acetylcholine receptors. It is associated with other autoimmune diseases such as thyroiditis (10%), systemic lupus erythematosus (2-8%), rheumatoid arthritis (4-7%), Sjögren's syndrome and polymyositis. It is not commonly found with scleroderma. We describe a case of scleroderma developing in a patient 6 years after the onset of myasthenia gravis. HLA-B8/DR3 may play a role in the association of the 2 conditions.
authors.affiliation: Department of Medicine, University of Illinois at Chicago 60612.
authors.forename: R
authors.initials: R
authors.lastname: Bhalla
authors.forename: W I
authors.initials: WI
authors.lastname: Swedler
authors.forename: M B
authors.initials: MB
authors.lastname: Lazarevic
authors.forename: H S
authors.initials: HS
authors.lastname: Ajmani
authors.forename: J L
authors.initials: JL
authors.lastname: Skosey
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D005260:Female; D006801:Humans; D009157:Myasthenia Gravis / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D011241:Prednisone / Q000627:therapeutic use; D011729:Pyridostigmine Bromide / Q000627:therapeutic use; D012595:Scleroderma, Systemic / Q000150:complications* / Q000188:drug therapy / Q000276:immunology
chemical_list: D000974:Antibodies, Antinuclear; D011729:Pyridostigmine Bromide; D011241:Prednisone