Dietary fatty acids and protection against experimental cardiac arrhythmias in rats.
Sudden cardiac death accounts for about 50% of total coronary disease mortality in westernized industrial countries. The lack of early symptoms for this disorder makes prevention the preferred strategy. In a rat model of cardiac ischemia, dietary n-6 (sunflower seed oil) and n-3 (fish-oil) polyunsaturated fatty acids were shown to protect against arrhythmia compared with saturated fat, with greatest protection observed with fish oil. The frequency of arrhythmia was similar with monounsaturated fat from olive oil and saturated fat.
Topping
D
D
Glenthorne Laboratory, CSIRO Division of Human Nutrition, Australia.
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000517:prevention & control*; D016757:Death, Sudden, Cardiac / Q000517:prevention & control*; D004041:Dietary Fats / Q000008:administration & dosage*; D004195:Disease Models, Animal; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage*; D051381:Rats
D004041:Dietary Fats; D005231:Fatty Acids, Unsaturated