title: Clinical cardiopulmonary bypass without systemic anticoagulation.
abstract: Heparin-coated perfusion systems have been used to perform cardiopulmonary bypass with decreased systemic heparin dosages. We report the case of a 60-year-old man with end-stage liver disease and severe aortic stenosis who underwent an aortic valve replacement without systemic anticoagulation, employing a heparin-coated perfusion system. In patients with a contraindication to systemic anticoagulation, cardiopulmonary bypass with a heparin-coated system without systemic anticoagulation may be a viable alternative.
authors.affiliation: Department of Cardiothoracic Surgery and Anesthesiology, University of Pittsburgh, PA 15216.
authors.forename: R D
authors.initials: RD
authors.lastname: Dowling
authors.forename: M E
authors.initials: ME
authors.lastname: Brown
authors.forename: R O
authors.initials: RO
authors.lastname: Whittington
authors.forename: J J
authors.initials: JJ
authors.lastname: Quinlan
authors.forename: J M
authors.initials: JM
authors.lastname: Armitage
mesh_terms: D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery*; D002315:Cardiopulmonary Bypass / Q000379:methods; D006350:Heart Valve Prosthesis / Q000379:methods; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D017093:Liver Failure / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion / Q000379:methods; D012720:Severity of Illness Index
chemical_list: D006493:Heparin