Carbamazepine-induced thrombocytopenia and leucopenia complicated by Henoch-Schönlein purpura symptoms.
A rare case of carbamazepine-induced leucopenia and thrombocytopenia complicated by Henoch-Schönlein purpura (HSP) symptoms is presented. Laboratory findings suggested that leucopenia and thrombocytopenia could be due to bone marrow suppression and HSP symptoms to an allergic reaction to carbamazepine. To the best of our knowledge this is the first report that carbamazepine may cause haematological disorders associated with symptoms of HSP by different mechanisms at the same time in the same patient.
Kaneko
K
K
Department of Paediatrics, Juntendo University School of Medicine, Tokyo, Japan.
Igarashi
J
J
Suzuki
Y
Y
Niijima
S
S
Ishimoto
K
K
Yabuta
K
K
D001853:Bone Marrow / Q000187:drug effects; D002220:Carbamazepine / Q000009:adverse effects*; D002648:Child; D003864:Depression, Chemical; D004342:Drug Hypersensitivity / Q000209:etiology; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000139:chemically induced*; D007970:Leukopenia / Q000139:chemically induced*; D013921:Thrombocytopenia / Q000139:chemically induced*
D002220:Carbamazepine