Is chronic graft versus host disease an autoimmune disease?
Chronic graft versus host disease continues to be a major problem following bone marrow transplantation even though the incidence and severity of acute graft versus host disease has been reduced. Recent investigations have suggested that the pathogenesis of chronic graft versus host disease is more similar clinically to an autoimmune disease than to acute graft versus host disease.
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Division of Research Immunology and Bone Marrow Transplantation, Children's Hospital, Los Angeles, California 90027.
D000818:Animals; D001327:Autoimmune Diseases / Q000276:immunology*; D015551:Autoimmunity / Q000276:immunology; D016026:Bone Marrow Transplantation / Q000009:adverse effects / Q000276:immunology; D002908:Chronic Disease; D016572:Cyclosporine / Q000276:immunology; D004195:Disease Models, Animal; D006086:Graft vs Host Disease / Q000276:immunology*; D006801:Humans; D051379:Mice
D016572:Cyclosporine