title: Low dose oral methotrexate treatment of multiple sclerosis: a pilot study.
abstract: An 18-month double-blind treatment of multiple sclerosis with low dose oral methotrexate showed it to be well tolerated and suggested effectiveness in exacerbating-remitting MS but not in the exacerbating progressive and chronic progressive stages.
authors.affiliation: Department of Neurology, University of Mississippi Medical Center, Jackson 39216.
authors.forename: R D
authors.initials: RD
authors.lastname: Currier
authors.forename: A F
authors.initials: AF
authors.lastname: Haerer
authors.forename: E F
authors.initials: EF
authors.lastname: Meydrech
mesh_terms: D000284:Administration, Oral; D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage*; D009103:Multiple Sclerosis / Q000188:drug therapy*; D010919:Placebos
chemical_list: D010919:Placebos; D008727:Methotrexate