title: Parathyroid scintigraphy with iodine-123 and 99mTc-sestamibi: imaging findings.
abstract: Subtraction scintigraphy with 99mTc-pertechnetate and 201Tl-chloride is widely used for localizing the parathyroid gland, but the sensitivity of this method averages only 55%. The sensitivity of scintigraphy is improved by using a combination of 99mTc-sestamibi and iodine-123. Parathyroid adenomas can also be localized with 99mTc-sestamibi alone by subtracting early images from late sequential images. The fast washout of 99mTc-sestamibi from the thyroid gland allows visualization of the parathyroid gland. The purpose of this essay is to illustrate the findings of abnormalities of the parathyroid glands when using a combination of 99mTc-sestamibi and iodine-123.
authors.affiliation: Department of Radiology, Medical College of Georgia, Augusta 30912-3910.
authors.forename: G J
authors.initials: GJ
authors.lastname: Burke
authors.forename: J P
authors.initials: JP
authors.lastname: Wei
authors.forename: E F
authors.initials: EF
authors.lastname: Binet
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D010280:Parathyroid Glands / Q000000981:diagnostic imaging*; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
chemical_list: D007457:Iodine Radioisotopes; D017256:Technetium Tc 99m Sestamibi