title: Prosthetic valve dysfunction in a Nigerian.
abstract: A case is presented of a mechanical cardiac valve dysfunction occurring in a 19-year-old Nigerian 7 years after valve surgery and presenting with cardiac failure, supraventricular tachycardia and later, cardiogenic shock but initially masquerading as generalised bleeding probably from Warfarin-drug interaction. The problem of management of an artificial heart valve in our setting is discussed.
authors.affiliation: Department of Medicine, University of Benin, Nigeria.
authors.forename: A O
authors.initials: AO
authors.lastname: Obasohan
authors.forename: V
authors.initials: V
authors.lastname: Ukoh
authors.forename: C O
authors.initials: CO
authors.lastname: Ajuyah
mesh_terms: D000328:Adult; D000962:Antimalarials / Q000009:adverse effects*; D004338:Drug Combinations; D004347:Drug Interactions; D017809:Fatal Outcome; D006333:Heart Failure / Q000209:etiology*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009549:Nigeria; D011475:Prosthesis Failure; D011739:Pyrimethamine / Q000009:adverse effects*; D012771:Shock, Hemorrhagic / Q000139:chemically induced*; D013413:Sulfadoxine / Q000009:adverse effects*; D013617:Tachycardia, Supraventricular / Q000209:etiology*; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D000962:Antimalarials; D004338:Drug Combinations; C001205:fanasil, pyrimethamine drug combination; D014859:Warfarin; D013413:Sulfadoxine; D011739:Pyrimethamine