title: A tight binding inhibitor of 5-aminoimidazole ribonucleotide carboxylase.
authors.affiliation: Department of Medicinal Chemistry and Pharmacognosy, Purdue University, West Lafayette, Indiana 47907-1333.
authors.forename: S M
authors.initials: SM
authors.lastname: Firestine
authors.forename: V J
authors.initials: VJ
authors.lastname: Davisson
mesh_terms: D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D007700:Kinetics; D009593:Nitroimidazoles / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology; D010766:Phosphorylation; D012265:Ribonucleotides / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology; D014542:Uridine Monophosphate / Q000031:analogs & derivatives*
chemical_list: C084132:5-amino-1-(5'-phosphoribofuranosyl)-4-nitroimidazole; D009593:Nitroimidazoles; D012265:Ribonucleotides; D014542:Uridine Monophosphate; D002262:Carboxy-Lyases; C022378:phosphoribosylaminoimidazole carboxylase