[Changes in the fibrinolytic activity in hypertension and acute cerebral infarction].
The fibrinolytic activity was measured in 30 patients with essential hypertension and 15 patients with acute cerebral infarction. The content of plasminogen (PLG) and plasminogen activator inhibitor-1(PAI-1) were higher in the patients with essential hypertension than in the controls. The results suggested that the fibrinolytic activity had a potential tendency towards decreasing in the patients with essential hypertension. The fibrinolytic activity was lower in the stage of cerebral attack and was higher in the stationary stage of acute cerebral infarction, which showed that a change of the fibrinolytic activity in acute cerebral infarction was related to the clinical course.
Guan
K J
KJ
First affiliated Hospital, Hunan Medical University, Changsha.
D000328:Adult; D000368:Aged; D002544:Cerebral Infarction / Q000097:blood*; D005260:Female; D005341:Fibrinolysin / Q000378:metabolism; D005342:Fibrinolysis; D006801:Humans; D006973:Hypertension / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010958:Plasminogen / Q000378:metabolism; D017395:Plasminogen Activator Inhibitor 1 / Q000097:blood; D010959:Tissue Plasminogen Activator / Q000097:blood
D017395:Plasminogen Activator Inhibitor 1; D010958:Plasminogen; D010959:Tissue Plasminogen Activator; D005341:Fibrinolysin