Micromanipulation of human gametes for assisted fertilization.
The techniques of partial zona dissection, subzonal sperm insertion, and intracytoplasmic sperm injection have been clinically employed to alleviate aberrations of human gamete interaction. This article reviews the current status of assisted fertilization technology and its relevance in treating male infertility. Indications for the application of each technique and factors affecting outcome are discussed.
Alikani
M
M
Center for Reproductive Medicine and Infertility, Cornell University Medical Center, New York, New York.
D004210:Dissection; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D007267:Injections; D007315:Insemination, Artificial / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D008297:Male; D008846:Micromanipulation / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D011247:Pregnancy; D011256:Pregnancy Outcome; D013084:Sperm-Ovum Interactions; D015044:Zona Pellucida