title: A unique case of apocrine carcinoma on the male pubic skin: histopathologic and ultrastructural observations.
abstract: We report a case of cutaneous adenocarcinoma on the pubic region of a 56-year-old male. The exophytic tumor showed solid, ductal, and glandular patterns with decapitation secretion and mucinous carcinoma-like nests. Despite the exophytic nature of the lesion, an invasive growth pattern into the deep dermis and subcutaneous fat was seen. An additional characteristic of this tumor was the presence of Paget's phenomenon. From these findings, we conclude that this tumor is an apocrine adenocarcinoma having an unusual clinical appearance and unique histopathological features which have some similarities to apocrine carcinoma of the breast and some to syringocystadenoma papilliferum and nipple adenomatosis.
authors.affiliation: Department of Dermatology, Boston University School of Medicine, MA 02118.
authors.forename: O
authors.initials: O
authors.lastname: Yamamoto
authors.forename: J
authors.initials: J
authors.lastname: Haratake
authors.forename: M
authors.initials: M
authors.lastname: Hisaoka
authors.forename: M
authors.initials: M
authors.lastname: Asahi
authors.forename: J
authors.initials: J
authors.lastname: Bhawan
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000473:pathology* / Q000648:ultrastructure; D006119:Groin; D006801:Humans; D015994:Incidence; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012878:Skin Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000648:ultrastructure