Carcinoma of the papilla of Vater in a brother and sister with familial adenomatous polyposis.
Familial adenomatous polyposis (FAP) is characterized by the development of adenomas throughout the entire gastrointestinal tract. We describe a brother and sister with FAP who developed adenocarcinoma around the papilla of Vater. Incidence, premalignancy, treatment and the need for prophylactic endoscopy are discussed.
Gerritsen
R T
RT
Department of Internal Medicine, Medical Centre, Leeuwarden, Netherlands.
Spoelstra
P
P
Breeuwsma
N G
NG
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000235:genetics; D014670:Ampulla of Vater; D001706:Biopsy; D003138:Common Bile Duct Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D010375:Pedigree