The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein.
Boulter
M K
MK
Tropical Pharmacology Unit, Liverpool School of Tropical Medicine, UK.
Bray
P G
PG
Howells
R E
RE
Ward
S A
SA
D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D002738:Chloroquine / Q000378:metabolism / Q000494:pharmacology*; D003891:Desipramine / Q000378:metabolism / Q000494:pharmacology*; D004351:Drug Resistance; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000378:metabolism
D001798:Blood Proteins; D002738:Chloroquine; D003891:Desipramine