title: Dorsal-ventral polarity in the Drosophila embryo.
abstract: Embryonic dorsal-ventral polarity in Drosophila is established through a series of successive steps and requires the functions of both maternal and zygotic genes. The graded distribution of the transcription factor dorsal in blastoderm nuclei represents the transition from the maternal to the zygotic program. This results in the activation of specific zygotic genes that act to create the regional pattern along this axis.
authors.affiliation: Department of Molecular Biology, Princeton University, New Jersey 08544.
authors.forename: R
authors.initials: R
authors.lastname: Steward
authors.forename: S
authors.initials: S
authors.lastname: Govind
mesh_terms: D000818:Animals; D001483:Base Sequence; D016764:Cell Polarity; D004247:DNA; D004268:DNA-Binding Proteins / Q000378:metabolism; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000378:metabolism; D010750:Phosphoproteins / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors
chemical_list: D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D009687:Nuclear Proteins; D010750:Phosphoproteins; D014157:Transcription Factors; C062236:dl protein, Drosophila; C077938:cact protein, Drosophila; D004247:DNA