The localization of sympathetic and vagal neurones innervating the carotid sinus in the rabbit.
The distribution of neurones innervating the carotid sinus of the rabbit was determined by inserting chips of horseradish peroxidase (HRP) into the adventitial layer of the carotid sinus. Labelled neurones were found in the superior cervical ganglion, along the cervical sympathetic trunk and in the nodose ganglion (mean counts of 1876, 139 and 232, respectively). No labelled neurones were located in the middle cervical ganglion or the stellate ganglion. Within the superior cervical ganglion, the fraction of labelled neurones found in equal longitudinal quadrants of the ganglion were, from rostral to caudal, 2%, 12%, 42% and 44%. Thus the majority of neurones were located in the caudal region of the superior cervical ganglion. The primary pathway for sympathetic fibres innervating the carotid sinus was shown to be in branches of the external carotid nerve. The greatest number of labelled neurones in the nodose ganglion were located in the most rostral quadrants of the ganglion.
Buller
K M
KM
Department of Physiology, Otago Medical School, Dunedin, New Zealand.
Bolter
C P
CP
D000818:Animals; D017776:Autonomic Pathways / Q000166:cytology / Q000502:physiology; D002346:Carotid Sinus / Q000294:innervation*; D005260:Female; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D008297:Male; D009474:Neurons / Q000502:physiology*; D009620:Nodose Ganglion / Q000166:cytology; D011817:Rabbits; D013233:Stellate Ganglion / Q000166:cytology; D017783:Superior Cervical Ganglion / Q000166:cytology; D013564:Sympathetic Nervous System / Q000166:cytology / Q000502:physiology*; D014630:Vagus Nerve / Q000166:cytology / Q000502:physiology*
D006735:Horseradish Peroxidase