Orofacial manifestations in primary immunodeficiencies: polymorphonuclear leukocyte defects.
The orofacial manifestations of 17 children with primary defects of polymorphonuclear leukocyte function are reported. Oral disease was commonly found and included recurrent oral ulceration (35% of patient group), oral candidiasis (29%), recurrent herpes labialis (12%), enamel hypoplasia (18%) and delayed tooth eruption (12%). Only 3 children had no orofacial disease. Cervical lymph node enlargement was present in 41% of the children.
Porter
S R
SR
University Department of Oral Medicine, Pathology and Microbiology, Bristol Dental School and Hospital, England.
Scully
C
C
D000293:Adolescent; D002180:Candidiasis, Oral / Q000276:immunology / Q000473:pathology; D002634:Chemotaxis, Leukocyte / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000473:pathology*; D008206:Lymphatic Diseases / Q000276:immunology / Q000473:pathology; D008297:Male; D009059:Mouth Diseases / Q000276:immunology / Q000473:pathology*; D009504:Neutrophils / Q000276:immunology* / Q000473:pathology; D010587:Phagocytosis / Q000276:immunology; D014456:Ulcer / Q000276:immunology / Q000473:pathology