Parainfluenza virus infection in adult bone marrow transplant recipients.
The clinical course of parainfluenza virus infection occurring in 8 of 265 (3%) adult bone marrow transplant recipients during 1991 was reviewed. Parainfluenza virus type 3 was isolated from all eight patients. The clinical course ranged from self-limited upper respiratory tract infections (2 patients) to severe lower respiratory tract disease (6 patients) associated with a 50% mortality. This study highlights the important role of community respiratory viruses such as parainfluenza virus in the etiology of pneumonia in immunocompromised adults.
Whimbey
E
E
Section of Infectious Diseases, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Vartivarian
S E
SE
Champlin
R E
RE
Elting
L S
LS
Luna
M
M
Bodey
G P
GP
D000328:Adult; D016026:Bone Marrow Transplantation; D006801:Humans; D016867:Immunocompromised Host; D007938:Leukemia / Q000150:complications; D008223:Lymphoma / Q000150:complications; D008875:Middle Aged; D010224:Parainfluenza Virus 3, Human / Q000302:isolation & purification*; D018184:Paramyxoviridae Infections / Q000150:complications / Q000382:microbiology* / Q000401:mortality; D011024:Pneumonia, Viral / Q000150:complications / Q000382:microbiology* / Q000401:mortality