Simultaneous occurrence of primary choroidal and cutaneous malignant melanoma and skin metastasis.
This case report describes the clinical and histopathological findings in a 65-year-old woman enucleated for a malignant choroidal melanoma. Simultaneously, an excision was performed of a cutaneous melanoma together with a satellite nodule presumed to be a metastasis from the cutaneous, superficial spreading melanoma. Six months later, chemotherapy for liver metastasis was given without effect. There were no signs of dysplastic nevus syndrome. A 39-year-old cousin, however, had been enucleated for a malignant choroidal melanoma. This sporadic case might suggest a common etiologic factor in the pathogenesis of multicentric melanomas.
Eide
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N
University Eye Department, National Hospital, University of Oslo, Norway.
Foerster
A
A
D000328:Adult; D000368:Aged; D002830:Choroid Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008545:Melanoma / Q000473:pathology* / Q000556:secondary*; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D014792:Visual Acuity