title: Hormone anabolic/catabolic balance in female endurance athletes.
abstract: The anabolic/catabolic hormone balance in 13 female endurance athletes was studied during basal conditions by comparing their serum concentrations of androgenic and catabolic steroids, growth hormone, insulin-like growth factor 1 (IGF-1) and insulin with corresponding values in 15 matched sedentary controls. Higher cortisol and lower levels sex hormone-binding globulin (SHBG) were found in the athletes, and these differences were enhanced depending on the degree of menstrual disorders. There was a negative correlation between cortisol and SHBG levels. No differences were found in concentrations of androgens, IGF-1 and insulin. The results indicate a normal anabolic activity in oligomenorrheic athletes, but due to their distinct hypercortisolism, the anabolic/catabolic hormone balance is changed to a predominantly catabolic state.
authors.affiliation: Department of Obstetrics and Gynecology, Karolinska Institute, Karolinska Hospital, Stockholm, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Lindholm
authors.forename: A L
authors.initials: AL
authors.lastname: Hirschberg
authors.forename: K
authors.initials: K
authors.lastname: Carlström
authors.forename: B
authors.initials: B
authors.lastname: von Schoultz
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000097:blood*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008598:Menstruation / Q000097:blood*; D009839:Oligomenorrhea / Q000097:blood*; D010807:Physical Endurance; D012420:Running; D012738:Sex Hormone-Binding Globulin / Q000032:analysis*
chemical_list: D012738:Sex Hormone-Binding Globulin; D006854:Hydrocortisone