title: [The role of bile acids in the regulation of human gallbladder filling].
abstract: An artificial increase of a pool of bile acids due to administration of dehydrocholic, chenodesoxycholic acid preparations and dry bile in 22 healthy people and 179 patients with chronic cholecystitis has been studied for its effect on regulation of the gallbladder filling on an empty stomach using daily echocholecystometry. Filling of the gallbladder under artificial sequestration of bile acids during duodenal probing, enterosorption and cholatogenic diarrhea was studied in 55 patients with cholecystitis. It has been proved that an increase of the pool of bile acids induces intensification of the gallbladder filling on an empty stomach, while a decrease of the pool, vice versa, causes attenuation of its filling. It is found out a size of a pool of bile acids in the human organism is an important humoral factor in the physiological mechanism of the gallbladder filling regulation.
authors.forename: V A
authors.initials: VA
authors.lastname: Berezovskyĭ
authors.forename: T D
authors.initials: TD
authors.lastname: Nykula
authors.forename: O B
authors.initials: OB
authors.lastname: Dynnyk
authors.forename: I V
authors.initials: IV
authors.lastname: Pavlyk
authors.forename: O M
authors.initials: OM
authors.lastname: Korychenskyĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002635:Chenodeoxycholic Acid / Q000494:pharmacology / Q000502:physiology*; D002764:Cholecystitis / Q000503:physiopathology*; D002908:Chronic Disease; D003685:Dehydrocholic Acid / Q000494:pharmacology*; D005260:Female; D005704:Gallbladder / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002635:Chenodeoxycholic Acid; D003685:Dehydrocholic Acid
vernacular_title: Rol zhovchnykh kyslot u reguliatsiĭ napovnennia zhovchnogo mikhura liudyny.