title: [Influence of ethanol and ethanol-induced lipid peroxidation on the steroidogenic activity of testicles].
abstract: Chronic alcohol intoxication results in the diminished testosterone level and activation of lipid peroxidation in rat testes. A significant decrease in 3 beta-hydroxysteroid-hydrogenase and 17-dehydrogenase activity has been observed in microsomes. Analogous shifts have been evoked in vitro by the induction of lipid peroxidation in microsomes. That permitted one to suppose that alcohol-induced alterations in tests are partially mediated by induction of lipid peroxidation.
authors.forename: M F
authors.initials: MF
authors.lastname: Kashko
authors.forename: A M
authors.initials: AM
authors.lastname: Khokha
authors.forename: S N
authors.initials: SN
authors.lastname: Antsulevich
authors.forename: N A
authors.initials: NA
authors.lastname: Doroshkevich
authors.forename: P P
authors.initials: PP
authors.lastname: Voronov
mesh_terms: D000437:Alcoholism / Q000201:enzymology / Q000378:metabolism*; D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000201:enzymology; D051381:Rats; D013256:Steroids / Q000096:biosynthesis*; D013737:Testis / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism
chemical_list: D013256:Steroids; D000431:Ethanol
vernacular_title: Vliianie étanola i indutsiruemogo im perekisnogo okisleniia lipidov na steroidogennuiu aktivnost' semennikov.