Effective population size, genetic diversity, and coalescence time in subdivided populations.
A formula for the effective population size for the finite island model of subdivided populations is derived. The formula indicates that the effective size can be substantially greater than the actual number of individuals in the entire population when the migration rate among subpopulations is small. It is shown that the mean nucleotide diversity, coalescence time, and heterozygosity for genes sampled from the entire population can be predicted fairly well from the theory for randomly mating populations if the effective population size for the finite island model is used.
Nei
M
M
Department of Biology, Pennsylvania State University, University Park 16802.
Takahata
N
N
D000818:Animals; D003198:Computer Simulation; D005787:Gene Frequency; D014644:Genetic Variation; D006579:Heterozygote; D006801:Humans; D008957:Models, Genetic; D011156:Population Density; D012689:Sequence Homology, Nucleic Acid; D013997:Time Factors