[Interaction between active metabolites of vitamin D3 and blood aluminum in chronic uremic patients on dialysis].
In the present study, the authors show that 1, 25 (OH)2 D3 given to hemodialyzed patients taking Al (OH)3, increased their plasma concentrations of Al. Two mechanism can explain this increase: increased intestinal absorption or decreased tissue storage of Al.
Panico
F
F
Ambulatorio di Nefrologia e Dialisi Nefrodial, Avellino.
Salvati
A
A
Scoppa
F
F
Testa
G F
GF
Capobianco
A
A
Pacia
S
S
Lauriello
F
F
Aquino
A
A
Tedesco
V
V
Taccone
W
W
D000293:Adolescent; D000328:Adult; D000368:Aged; D000535:Aluminum / Q000494:pharmacology*; D000536:Aluminum Hydroxide / Q000493:pharmacokinetics / Q000627:therapeutic use; D002117:Calcitriol / Q000494:pharmacology* / Q000627:therapeutic use; D002908:Chronic Disease; D003676:Deferoxamine; D004347:Drug Interactions; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000188:drug therapy / Q000209:etiology; D007408:Intestinal Absorption / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D014018:Tissue Distribution; D014511:Uremia / Q000097:blood* / Q000150:complications / Q000628:therapy
D000536:Aluminum Hydroxide; D000535:Aluminum; D002117:Calcitriol; D003676:Deferoxamine
Interazione tra metaboliti attivi della vitamina D3 ed alluminemia nell'uremico cronico in dialisi.