title: Vesicular stomatitis virus M protein may be inside the ribonucleocapsid coil.
abstract: Vesicular stomatitis virus is an enveloped virus with an external glycoprotein G and a nucleocapsid that form, together with the M protein, a tight helically coiled structure: the skeleton. Negative staining and immunoelectron microscopy studies on skeleton preparations were performed to determine the localization of the M protein. These studies have resulted in a new model for the structure of rhabdoviruses in which the nucleocapsid is wound around a core containing the M protein. This model predicts contact between M and lipid only at the extreme ends of the skeleton, which is confirmed by skeleton-liposome binding studies.
authors.affiliation: EMBL Grenoble Outstation, France.
authors.forename: A
authors.initials: A
authors.lastname: Barge
authors.forename: Y
authors.initials: Y
authors.lastname: Gaudin
authors.forename: P
authors.initials: P
authors.lastname: Coulon
authors.forename: R W
authors.initials: RW
authors.lastname: Ruigrok
mesh_terms: D002213:Capsid / Q000378:metabolism / Q000648:ultrastructure*; D006046:Gold; D007150:Immunohistochemistry; D008081:Liposomes / Q000378:metabolism; D008961:Models, Structural; D012367:RNA, Viral / Q000378:metabolism / Q000648:ultrastructure*; D012209:Rhabdoviridae / Q000648:ultrastructure; D012995:Solubility; D014721:Vesicular stomatitis Indiana virus / Q000378:metabolism / Q000648:ultrastructure*; D014758:Viral Core Proteins / Q000378:metabolism / Q000648:ultrastructure*; D014763:Viral Matrix Proteins / Q000378:metabolism / Q000648:ultrastructure*
chemical_list: D008081:Liposomes; D012367:RNA, Viral; D014758:Viral Core Proteins; D014763:Viral Matrix Proteins; D006046:Gold