Precipitous hypotension after nifedipine in pheochromocytoma: report of 2 cases.
Two patients with pheochromocytoma initially responded to oral or sublingual nifedipine with marked reduction in systolic blood pressure (range 50-160 mmHg) without concomitant increment in the heart rate or clinical consequences. This could possibly be due to the combination of hypovolemia and negative inotropism.
Tantawanichpisal
D
D
Department of Medicine, Faculty of Medicine, Prince of Songkhla University, Thailand.
Rujiwanichkul
K
K
Yipintsoi
T
T
D000310:Adrenal Gland Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced*; D009543:Nifedipine / Q000009:adverse effects*; D010673:Pheochromocytoma / Q000188:drug therapy* / Q000503:physiopathology
D009543:Nifedipine