[Quantitative study of diabetic retinopathy by computerized image analysis].
Composite fluorescein angiographic pictures of 66 eyes with diabetic retinopathy and nonperfusion areas were studied by computerized image analysis, and the ratio of the nonperfusion area to the disc area was calculated. There were 49 eyes with neovascularization (NV), in which the mean ratio +/- standard error was 46.33 +/- 7.01 (8.15 to 298.26), and the corresponding value in the other 17 eyes without NV was 6.90 +/- 1.31 (2.20 to 21.37), the difference being very significant. When the ratios were under 10, from 10 to 30, or over 30, the percentages of eyes manifesting NV were 13.3%, 81.8% and 100% respectively. In the 49 eyes with NV, the majority of the total 267 neovascular clusters were distributed 4-6 DD away from the optic disc, which itself was involved only in 18 eyes.
Zhang
H R
HR
Department of Ophthalmology, Third Teaching Hospital, Beijing Medical University.
Tian
L
L
D000328:Adult; D003930:Diabetic Retinopathy / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D009898:Optic Disk / Q000473:pathology; D015861:Retinal Neovascularization / Q000473:pathology*