Effect of concentric exercise on serum muscle and collagen markers.
The effect of an acute bout of high-intensity concentric exercise on serum muscle and collagen marker proteins was studied in nine male students. The muscle-derived serum carbonic anhydrase III, myoglobin, and creatine kinase all increased as a result of the exercise. Serum type I procollagen carboxyterminal propeptide decreased at first but started to increase 2 days after the exercise. Serum galactosylhydroxylysyl glucosyltransferase was elevated immediately after the exercise. No significant changes were seen in the concentrations of serum amino-terminal propeptide of type III procollagen or 4-hydroxyproline. It seems that a single bout of heavy concentric exercise causes protein leakage from muscles and probably from the collagen-synthesizing cells of the connective tissue, which may be accompanied by an initial decrease and a subsequent increase in type I collagen production. The activation of type I collagen production seems to depend on the strain and damage of the musculoskeletal system.
Virtanen
P
P
Department of Sports Medicine, University of Oulu, Finland.
Viitasalo
J T
JT
Vuori
J
J
Väänänen
K
K
Takala
T E
TE
D000328:Adult; D015415:Biomarkers; D001769:Blood / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D009132:Muscles / Q000378:metabolism*; D005082:Physical Exertion; D013739:Testosterone / Q000097:blood
D015415:Biomarkers; D013739:Testosterone; D003094:Collagen; D006854:Hydrocortisone