[Labial herpes in patients with affective disorders receiving long-term lithium carbonate].
Lithium carbonate has been administered to 69 patients (45 women and 24 men) for 1-17 years as affective disorders prevention. Its effect on the recurrence and clinical course of labial herpes infection has been analysed both prior to and after the administration of lithium carbonate. Labial herpes has been diagnosed in 28 patients before lithium prophylaxis. The drug significantly decreased virus infection recurrence incidence in this group. No labial herpes recurrence has been noted in 13 patients after the treatment. Lithium efficiency has not been dependent on patients' age, duration of therapy, and lithium levels in both blood serum and erythrocytes. These results suggest, that lithium salts may be effective in certain herpes simplex infections at doses used for prevention affective disorders.
Rybakowski
J
J
Katedry i Kliniki Psychiatrii AM, Poznaniu.
Strzyzewski
W
W
Zelechowska-Ruda
E
E
Chłopocka-Woźniak
M
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006560:Herpes Labialis / Q000150:complications / Q000517:prevention & control*; D006801:Humans; D016651:Lithium Carbonate / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications / Q000188:drug therapy*; D012008:Recurrence
D016651:Lithium Carbonate
Opryszczka wargowa u osób z chorobami afektywnymi otrzymujacymi długotrwale weglan litu.