[The effect of diprivan on the indices of central hemodynamics and the heart conduction system].
Using impedance tetrapolar plethysmography and transesophageal electrical stimulation of the left ventricle, changes in central hemodynamic parameters have been assessed in 46 women during brief (up to 10 min) anesthesias with diprivanum. Bolus injection of diprivanum at a dose of 2.5 mg per 1 kg body weight was used. It has been demonstrated that diprivanum administration decreased BP, which was associated with a drop in total peripheral resistance and stroke volume that led to the absence of compensatory tachycardia to an increase in the cardiac output. The absence of compensatory tachycardia upon diprivanum administration is accounted for by a combined effect of vagotonic diprivanum action and its ability to inhibit moderately the automatic function of the sinoatrial node.
Malyshev
V D
VD
Zhdanov
A M
AM
Andriukhin
I M
IM
Omarov
Kh T
KhT
Kheĭmets
G I
GI
Sviridov
S V
SV
Vedenina
I V
IV
Orudzheva
S A
SA
D000328:Adult; D000771:Anesthesia, Intravenous; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery*; D006329:Heart Conduction System / Q000187:drug effects* / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D015742:Propofol
D015742:Propofol
Vliianie diprivana na pokazateli tsentralńoĭ gemodinamiki i provodiashchuiu sistemu serdtsa.