The community effect, dorsalization and mesoderm induction.
The community effect is an interaction among muscle progenitor cells of amphibian gastrula, and is necessary for the initiation of muscle-specific gene expression. Dorsalization provides a signal that can convert ventral mesoderm cells to a muscle fate. Neither process involves mesoderm-inducing molecules. We suggest that the developmental significance of the community effect is to generate homogeneous but clearly demarcated groups of cells from progenitor cells arranged in a continuous gradient of developmental potential.
Gurdon
J B
JB
Wellcome CRC Institute, University of Cambridge, UK.
Kato
K
K
Lemaire
P
P
D000818:Animals; D004627:Embryonic Induction; D005775:Gastrula; D008648:Mesoderm; D009132:Muscles / Q000166:cytology / Q000196:embryology*