title: A fluid dynamic analysis of a rotary blood pump for design improvement.
abstract: The proper design of a left ventricular assist device (LVAD) requires an understanding of the pump's fluid dynamic and biocompatible properties. A hydraulically efficient system minimizes the power required for pumping. Biocompatibility refers to the ability to pump blood with minimal hemolysis and thrombus formation. Typically, shear stresses below a threshold level will not damage blood significantly. A fluid dynamic analysis of a prototype centrifugal pump designed for use as an LVAD was performed to establish flow characteristics. A flow visualization technique using Amberlite particles suspended in a glycerin/water blood analogue was used. The system was illuminated with a 1 mm planar beam strobed helium-neon laser, and the results were recorded photographically. An analysis of photographs revealed laminar and turbulent flows with vortices within an illuminated plane in both the inlet and outlet port areas. From these data, velocity and shear stress profiles were generated that showed possible areas of improvement. It was concluded that the outlet port design could be improved by changing its angle and the continuity of its expansion. The inlet port could also be improved by smoothing the transition area between the inlet tube and the pump body to allow for gradual acceleration of the entering fluid.
authors.affiliation: Department of Surgery, Baylor College of Medicine, Houston, Texas 77030.
authors.forename: J
authors.initials: J
authors.lastname: Treichler
authors.forename: S E
authors.initials: SE
authors.lastname: Rosenow
authors.forename: G
authors.initials: G
authors.lastname: Damm
authors.forename: K
authors.initials: K
authors.lastname: Naito
authors.forename: Y
authors.initials: Y
authors.lastname: Ohara
authors.forename: K
authors.initials: K
authors.lastname: Mizuguchi
authors.forename: K
authors.initials: K
authors.lastname: Makinouchi
authors.forename: S
authors.initials: S
authors.lastname: Takatani
authors.forename: Y
authors.initials: Y
authors.lastname: Nosé
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D001792:Blood Platelets / Q000502:physiology; D004867:Equipment Design; D004912:Erythrocytes / Q000502:physiology; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000502:physiology*; D006461:Hemolysis / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D016277:Ventricular Function, Left / Q000502:physiology