Estimation of double-strand break quality based on track-structure calculations.
The aim of this study was to investigate whether double-strand break (DSB) quality is related to the complexity of radiation-induced damage or to the spatial distribution of initial DSBs. The analysis was based on track structure calculations and DNA damage modelling. The results obtained indicate that the quality of DSBs is related to their initial spatial distribution rather than to their complexity.
Michalik
V
V
Institute of Radiation, Dosimetry, Czech Republic.
D004249:DNA Damage; D008957:Models, Genetic