[Synthesis and antitumor activity of beta-diketonato complexes of titanium].
Nine cis-beta-diketonato titanium (IV) complexes were synthesized and their chemical structures were confirmed by IR, UV spectra and elemental analyses. Among them 6 complexes have not been reported before. Preliminary pharmacological experiments showed that this kind of complexes were active against tumors.
Zhao
Y W
YW
Department of Pharmacy, Shandong Medical University, Jinan.
Yuan
H L
HL
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D051379:Mice; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000627:therapeutic use; D012510:Sarcoma 180 / Q000188:drug therapy; D014025:Titanium
D000970:Antineoplastic Agents; D009942:Organometallic Compounds; D014025:Titanium