title: [Primary antiphospholipid syndrome in juvenile ischemic stroke].
abstract: Results obtained in three patients with juvenile ischemic stroke and criteria of primary antiphospholipid syndrome is reported. These patients are selected out from a series of 12 patients with 18-mounts follow-up. Lupic anticoagulant and anticardiolipin antibodies were found in two of three patients and one patient show anticardiolipin antibodies with negative lupic anticoagulant. All others coagulation proteins examined (antithrombin III, plasminogen, protein C and protein S) were normal. We conclude that antiphospholipid antibodies are associated with increase risk of thrombosis. Therefore should be systematically investigated in juvenile ischemic stroke of unknown aetiology.
authors.affiliation: Servicio de Neurología, Hospital Clínico Universitario, Salamanca.
authors.forename: J
authors.initials: J
authors.lastname: Cacho
authors.forename: J F
authors.initials: JF
authors.lastname: Tomás
authors.forename: J
authors.initials: J
authors.lastname: Arcaya
authors.forename: V
authors.initials: V
authors.lastname: León
authors.forename: I
authors.initials: I
authors.lastname: Alberca
authors.forename: V
authors.initials: V
authors.lastname: Vicente
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear; D017152:Antibodies, Antiphospholipid / Q000276:immunology*; D016736:Antiphospholipid Syndrome / Q000175:diagnosis / Q000276:immunology*; D001777:Blood Coagulation; D001798:Blood Proteins / Q000276:immunology; D002545:Brain Ischemia / Q000175:diagnosis / Q000276:immunology*; D002308:Cardiolipins / Q000276:immunology; D002536:Cerebral Arteries / Q000503:physiopathology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D008297:Male; D010718:Phosphatidylserines / Q000276:immunology
chemical_list: D000974:Antibodies, Antinuclear; D017152:Antibodies, Antiphospholipid; D001798:Blood Proteins; D002308:Cardiolipins; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010718:Phosphatidylserines
vernacular_title: Síndrome antifosfolipídico primario en el ictus isquémico juvenil.