[Structural reorganization and change in the lipid composition of rat liver microsomes in chlorophos poisoning].
The influence of chlorophos on the endoplasmatic reticulum of rat liver has been studied using the methods of gas-liquid chromatography and fluorescence. Experiments have demonstrated an increase of lysophosphatidylethanolamine, total phospholipids, unsaturated fatty acids (C20:4 n6, C18:1 n11, C18:1 n7) and a decrease of phosphatidylserine and phosphatidylethanolamine. Changes in microviscosity and surface charge were also shown.
Boldeskul
A E
AE
Gubskiĭ
Iu I
IuI
Mel'nik
A A
AA
Fal'kovskaia
E N
EN
D000818:Animals; D004721:Endoplasmic Reticulum / Q000187:drug effects*; D005227:Fatty Acids / Q000378:metabolism; D050356:Lipid Metabolism; D008246:Lysophospholipids / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects*; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010718:Phosphatidylserines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D014236:Trichlorfon / Q000506:poisoning*; D014783:Viscosity
D005227:Fatty Acids; D008246:Lysophospholipids; D010714:Phosphatidylethanolamines; D010718:Phosphatidylserines; D010743:Phospholipids; C008301:lysophosphatidylethanolamine; D014236:Trichlorfon
Strukturnye perestroĭki i izmenenie lipidnogo sostava mikrosom pechenie krys pri intoksikatsii khlorofosom.