title: Single dose of ofloxacin treatment in women with dysuria and frequency.
abstract: The efficacy of single dose ofloxacin in lower urinary tract infections was investigated in this study. Fifty-one women with complaints of dysuria and frequency were treated with a single dose of 400 mg ofloxacin orally. The results of urinalysis and urine culture which were performed 4-7 days after the administration of the drug were evaluated. Thirty-eight of the 47 evaluable patients (80.85%) were asymptomatic with normal urinalysis and sterile urine, thus cured. The data of the study suggest that single dose ofloxacin may be the first treatment option in the particular group of women with uncomplicated urinary tract infection.
authors.affiliation: Department of Urology, Marmara University, School of Medicine, Istanbul, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Simşek
authors.forename: O
authors.initials: O
authors.lastname: Dillioğlugil
authors.forename: Y
authors.initials: Y
authors.lastname: Ilker
authors.forename: A
authors.initials: A
authors.lastname: Akdaş
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000892:Anti-Infective Agents, Urinary / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D015242:Ofloxacin / Q000008:administration & dosage* / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D014555:Urination Disorders / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology / Q000652:urine; D014563:Urodynamics
chemical_list: D000892:Anti-Infective Agents, Urinary; D015242:Ofloxacin