title: Viscosity sensing with lamb-wave microsensor: dimethylsulfoxide solution viscosity as a function of temperature.
abstract: Recently, a new microsensor employing low-velocity ultrasonic Lamb waves was developed and demonstrated to be capable of measuring the viscosity of solutions in small volumes. The microsensor, when attached to a temperature-controlled stage, can measure viscosity as a function of temperature. In this investigation, the ultrasonic Lamb-wave oscillator is employed to experimentally measure the viscosity of dimethylsulfoxide (Me2SO) solutions as a function of temperature. The microsensor and the experimental procedure are described and results for 1M, 3M, and 5M Me2SO aqueous solutions are presented. Dimethylsulfoxide is a compound commonly employed as a cryoprotectant in cryopreservation, the low-temperature preservation of biological materials. The temperature dependence of viscosity obtained through this study can be used in determining the probability for ice nucleation in biological materials, a parameter of importance during cryopreservation.
authors.affiliation: Department of Mechanical Engineering, University of California at Berkeley 94720.
authors.forename: T K
authors.initials: TK
authors.lastname: Eto
authors.forename: B J
authors.initials: BJ
authors.lastname: Costello
authors.forename: S W
authors.initials: SW
authors.lastname: Wenzel
authors.forename: R M
authors.initials: RM
authors.lastname: White
authors.forename: B
authors.initials: B
authors.lastname: Rubinsky
mesh_terms: D002138:Calibration; D015925:Cryopreservation / Q000379:methods; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D005069:Evaluation Studies as Topic; D007053:Ice / Q000009:adverse effects; D009991:Oscillometry / Q000295:instrumentation / Q000379:methods; D012996:Solutions; D013696:Temperature; D014465:Ultrasonics; D014783:Viscosity; D014867:Water / Q000737:chemistry
chemical_list: D007053:Ice; D012996:Solutions; D014867:Water; D004121:Dimethyl Sulfoxide