Full-field electroretinogram in a patient with cutaneous melanoma-associated retinopathy.
A patient operated for malignant melanoma developed night blindness and a sensation of shimmering light, strong enough to make him unable to work. Shortly afterwards, melanoma metastases became apparent. A full-field ERG examination showed absence of rod responses but normal cone amplitudes, suggesting a malfunctioning rod system in the retina. The patient was not on chemotherapy. A few similar cases have previously been reported. The disease appears to differ from the cancer-associated retinopathy (CAR) syndrome, which affects mainly the photoreceptor cells.
Andréasson
S
S
Department of Ophthalmology, University of Lund, Sweden.
Ponjavic
V
V
Ehinger
B
B
D004596:Electroretinography; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000556:secondary; D008875:Middle Aged; D009755:Night Blindness / Q000209:etiology / Q000503:physiopathology; D012164:Retinal Diseases / Q000209:etiology / Q000503:physiopathology*; D017948:Retinal Rod Photoreceptor Cells / Q000503:physiopathology; D012878:Skin Neoplasms / Q000150:complications*; D014786:Vision Disorders / Q000473:pathology