Timing of exposures in ultrasonic hemorrhage of murine lung.
Pressure thresholds for lung hemorrhage by exposure to low-temporal-average-intensity, pulsed ultrasound are of the order of 1 MPa. Earlier evidence suggested that ultrasound modifies the tissue over short periods of time in such a way that the nonthermal action of ultrasound is enhanced. Measurements of thresholds (1) for hemorrhage and (2) for penetration of the hemorrhage through the murine lung in which a given "on-time" was presented to the tissue over periods of time up to 3 min support the hypothesis.
Raeman
C H
CH
Department of Electrical Engineering, University of Rochester, NY 14627.
Child
S Z
SZ
Carstensen
E L
EL
D000818:Animals; D006470:Hemorrhage / Q000209:etiology*; D055370:Lung Injury; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D013997:Time Factors; D014465:Ultrasonics / Q000009:adverse effects*