title: [Sertoli-Leydig tumors in children. 2 case reports].
abstract: Sertoli-Leydig tumors stem from the mesenchyma and sexual cords of the embryonic gonad. Two cases are reported. One manifested as symptoms of virilization in a 12 year old girl. The other patient developed adnexal torsion at the age of five years. Pelvic ultrasonography visualized the tumor in both cases. Increased production of ovarian androgens suggested the diagnosis in the first case. Histological studies disclosed intermediate differentiation in the first case and tubular differentiation in the second. These tumors usually exhibit low-grade malignancy and unilateral salpingo-oophorectomy ensures recovery in most instances.
authors.affiliation: Service de Pédiatrie, Hôpital de Cimiez, Nice.
authors.forename: R
authors.initials: R
authors.lastname: Mariani
authors.forename: A
authors.initials: A
authors.lastname: Taleb-Figueroa
authors.forename: F
authors.initials: F
authors.lastname: Bastiani-Griffet
authors.forename: F
authors.initials: F
authors.lastname: Monpoux
authors.forename: A
authors.initials: A
authors.lastname: Coussement
authors.forename: R
authors.initials: R
authors.lastname: Loubière
mesh_terms: D000291:Adnexal Diseases / Q000209:etiology*; D000728:Androgens / Q000097:blood; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007984:Leydig Cell Tumor / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D010052:Ovariectomy; D012707:Sertoli Cell Tumor / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014102:Torsion Abnormality; D014463:Ultrasonography; D014770:Virilism / Q000209:etiology*
chemical_list: D000728:Androgens
vernacular_title: Tumeurs de Sertoli-Leydig de l'enfant. A propos de deux observations.