title: Requiem for distributive segregation: achiasmate segregation in Drosophila females.
abstract: The segregation of achiasmate chromosome pairs at meiosis I is not brought about by a single 'distributive system' as previously thought, but rather by two separate mechanisms. One system uses the pairing of proximal heterochromatic sequences to mediate the segregation of achiasmate homologs-an observation that, at long last, defines a function for heterochromatin. The other system facilitates the segregation of heterologous chromosomes, by an as yet undiscovered mechanism.
authors.affiliation: Department of Genetics, University of California, Davis 95616.
authors.forename: R S
authors.initials: RS
authors.lastname: Hawley
authors.forename: W E
authors.initials: WE
authors.lastname: Theurkauf
mesh_terms: D000818:Animals; D002503:Centromere / Q000502:physiology; D002875:Chromosomes / Q000502:physiology; D003434:Crossing Over, Genetic; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D006570:Heterochromatin / Q000502:physiology / Q000648:ultrastructure; D016547:Kinesins; D008540:Meiosis; D008868:Microtubule Proteins / Q000502:physiology; D008957:Models, Genetic; D009630:Nondisjunction, Genetic; D012689:Sequence Homology, Nucleic Acid
chemical_list: D029721:Drosophila Proteins; D006570:Heterochromatin; D008868:Microtubule Proteins; C080298:Nod protein, Drosophila; D016547:Kinesins