title: Familial occurrence of periapical cemental dysplasia.
abstract: A family with periapical cemental dysplasia is reported. The affected individuals displayed classical features of periapical cemental dysplasia on radiographic examination. The lesions consisted chiefly of radiolucent areas; however, some had central areas of radiodensity. Histopathological examination of one of the lesions revealed fibrous elements containing fused dense sclerotic cemental masses. Familial incidence of florid cemento-osseous dysplasia with an autosomal mode of inheritance has been reported previously. The condition described in this report appears to be different. However, the two conditions may be part of a spectrum occurring in a single genetic entity with the diversity possibly resulting from variable expressivity of a single gene.
authors.affiliation: Department of Medical Genetics St. Mary's Hospital, Manchester, UK.
authors.forename: N S
authors.initials: NS
authors.lastname: Thakkar
authors.forename: K
authors.initials: K
authors.lastname: Horner
authors.forename: P
authors.initials: P
authors.lastname: Sloan
mesh_terms: D002485:Cementoma / Q000000981:diagnostic imaging* / Q000235:genetics*; D003739:Dental Cementum / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D010483:Periapical Diseases / Q000000981:diagnostic imaging* / Q000235:genetics; D011859:Radiography