title: Differential diagnosis between granular corneal dystrophy Groenouw type I and paraproteinemic crystalline keratopathy.
abstract: A case of corneal opacities in a leukemic patient with an M-component in the serum proteins is presented, and a comparison is made to patients with granular corneal dystrophy Groenouw type I. The corneal deposits associated with the two conditions may appear identical with slit-lamp biomicroscopy. Granular dystrophy patients, however, show a normal serum immunoglobulin pattern in contrast to patients with paraproteinemic crystalline keratopathy. The two entities can therefore be distinguished from each other by a serum electrophoresis.
authors.affiliation: Department of Ophthalmology, Arhus University Hospital, Denmark.
authors.forename: H U
authors.initials: HU
authors.lastname: Møller
authors.forename: N
authors.initials: N
authors.lastname: Ehlers
authors.forename: M
authors.initials: M
authors.lastname: Bojsen-Møller
authors.forename: A E
authors.initials: AE
authors.lastname: Ridgway
mesh_terms: D003315:Cornea / Q000648:ultrastructure; D003316:Corneal Diseases / Q000175:diagnosis*; D003317:Corneal Dystrophies, Hereditary / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008875:Middle Aged; D010265:Paraproteinemias / Q000175:diagnosis*
chemical_list: D007136:Immunoglobulins