The use of antiepileptic drug levels in children: a survey of Canadian pediatric neurologists.
There are 60 pediatric neurologists in Canada. Replies were received from 56 in response to a survey regarding the use and perceived value of antiepileptic drug (AED) levels. AED levels are frequently ordered and influence clinical care. There were, however, discrepancies among pediatric neurologists regarding the upper and lower limits of the "therapeutic ranges" and the clinical application of levels. We suggest that both the value and use of AED levels needs further study.
Dooley
J M
JM
Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.
Camfield
P R
PR
Camfield
C S
CS
Gordon
K E
KE
Fraser
A D
AD
D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D001291:Attitude of Health Personnel; D002220:Carbamazepine / Q000031:analogs & derivatives / Q000097:blood / Q000627:therapeutic use; D002648:Child; D004827:Epilepsy / Q000097:blood / Q000188:drug therapy; D005013:Ethosuximide / Q000097:blood / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D010634:Phenobarbital / Q000097:blood / Q000627:therapeutic use; D014635:Valproic Acid / Q000097:blood / Q000627:therapeutic use
D000927:Anticonvulsants; D002220:Carbamazepine; D005013:Ethosuximide; D014635:Valproic Acid; C012227:carbamazepine epoxide; D010634:Phenobarbital