Bronchiolitis obliterans organizing pneumonia associated with essential mixed cryoglobulinemia.
Bronchiolitis obliterans organizing pneumonia (BOOP) is an uncommon and underrecognized pathologic finding observed in a variety of syndromes including connective tissue diseases. Although lung involvement in essential mixed cryoglobulinemia (EMC) has been reported, there are no previous reports of BOOP in EMC. We report herein a case of longstanding EMC associated with interstitial and cavitary lung disease histologically consistent with BOOP. A theory of a possible etiologic basis for the development of BOOP in patients with connective tissue diseases is discussed.
Zackrison
L H
LH
Division of Rheumatology, Immunology, Georgetown University Medical Center, Washington, DC 20007.
Katz
P
P
D001706:Biopsy; D001989:Bronchiolitis Obliterans / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D003449:Cryoglobulinemia / Q000150:complications*; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D013902:Radiography, Thoracic
D008775:Methylprednisolone