A randomised, double-blind study on the efficacy of Tołpa Torf Preparation (TTP) in the treatment of recurrent respiratory tract infections.
TTP is a new immunomodulating drug of natural origin, registered in Poland for human use. In the randomised, double blind study to assess the therapeutic efficacy of the Tołpa Torf Preparation (TTP) in the recurrent respiratory tract infectious participated 39 young patients (age 16-22). TTP was administered orally, 5 mg daily for three weeks. During 3 months follow-up period favourable results of treatment were obtained in 14 of 20 TTP treated patients and in 8 of 19 of the placebo patients. The therapeutic effects were seen even after the 6 months follow-up period. The phagocytic activity of granulocytes was significantly stimulated in the TTP--treated patients but not in the placebo-treated patients. The results suggest that TTP is effective drug in the treatment of recurrent respiratory tract infections with undefined infectious etiology. In the period of the treatment as well as during 6 months observation no side effects were noticed.
Jankowski
A
A
Department of Pediatric Propedeutics, University Medical School, Wrocław, Poland.
Nienartowicz
B
B
Polańska
B
B
Lewandowicz-Uszyńska
A
A
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000596:Amino Acids / Q000627:therapeutic use*; D002241:Carbohydrates / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006812:Humic Substances / Q000627:therapeutic use*; D007369:Interferon Inducers / Q000627:therapeutic use*; D008297:Male; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D012987:Soil / Q000032:analysis*; D014574:Uronic Acids / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000596:Amino Acids; D002241:Carbohydrates; D004338:Drug Combinations; D006812:Humic Substances; D007369:Interferon Inducers; D012987:Soil; C084029:Tolpa; D014574:Uronic Acids