title: Temporal changes in myocardial uptake on serial bone scans in two cases of presumed senile cardiac amyloidosis.
abstract: Two unusual examples of cardiac uptake in elderly patients who had received serial bone scans, one with a "waxing" and the other with a "waning" pattern of myocardial tracer uptake, are presented. An apparent temporal discordance between echocardiographic and scintigraphic findings is noted. Neither of the two patients had clinical, electrocardiographic, or other laboratory evidence of old or new myocardial infarction. Possible causes for the temporal changes are described. Presumptive diagnoses of senile cardiac amyloidosis were made based on clinical findings, noninvasive imaging, and comparison with a historic cohort at the Veterans Administration Medical Center in Houston.
authors.affiliation: Department of Radiology (Nuclear Medicine Section), Baylor College of Medicine, Houston, Texas.
authors.forename: R M
authors.initials: RM
authors.lastname: Davidson
authors.forename: D S
authors.initials: DS
authors.lastname: Lin
authors.forename: M
authors.initials: M
authors.lastname: Klima
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000686:Amyloidosis / Q000000981:diagnostic imaging*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D009202:Cardiomyopathies / Q000000981:diagnostic imaging*; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013669:Technetium Tc 99m Medronate; D016698:Technetium Tc 99m Pyrophosphate; D013997:Time Factors
chemical_list: D016698:Technetium Tc 99m Pyrophosphate; D013669:Technetium Tc 99m Medronate