title: Evaluation of complications during and after conscious sedation for endoscopy using pulse oximetry.
abstract: All events prolonging an endoscopic procedure or recovery, or requiring a medication or an intervention, were analyzed from a consecutive sample of 508 patients receiving conscious sedation. Although 102 events were identified (20%), 33 of these (7%) were major. These included four episodes of apnea and four patients with a prompt and sustained fall in oxygenation during the procedure; 19 additional patients had a decrease to less than 89% in oxygen saturation in the 30 minutes after the completion of the procedure. The patients with observed events had significantly more major illnesses, a higher fraction older than 70 years, and a higher fraction of endoscopic retrograde cholangiopancreatography than those without events (p < 0.05) but had a similar dose of sedative medications, mean age, and fraction of colonoscopies.
authors.affiliation: Division of Gastroenterology, Edward Hines Jr. VAMC, Hines, IL 60141.
authors.forename: F L
authors.initials: FL
authors.lastname: Iber
authors.forename: M
authors.initials: M
authors.lastname: Sutberry
authors.forename: R
authors.initials: R
authors.lastname: Gupta
authors.forename: D
authors.initials: D
authors.lastname: Kruss
mesh_terms: D000367:Age Factors; D000368:Aged; D001049:Apnea / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003113:Colonoscopy / Q000009:adverse effects*; D016292:Procedural Sedation; D016145:Endoscopy, Digestive System / Q000009:adverse effects*; D006801:Humans; D007040:Hypoventilation / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D008614:Meperidine / Q000627:therapeutic use; D008874:Midazolam / Q000627:therapeutic use; D008991:Monitoring, Physiologic / Q000379:methods*; D010092:Oximetry; D012307:Risk Factors
chemical_list: D008614:Meperidine; D008874:Midazolam