title: [Smoking and gastrointestinal function].
abstract: Aspects of gastrointestinal function pathogenetically related to peptic ulcer have been studied extensively. Even as to secretion of gastric acid and pancreatic bicarbonate a definite statement concerning the impact of smoking is difficult. Most of the available studies found that smoking increases acid secretion and decreases pancreatic secretion. This may, at least in part, explain the untoward effect of smoking in ulcer disease. Gastric emptying is slightly decreased by smoking. Gastro-oesophageal and duodenogastric reflux are obviously not influenced to a clinically relevant extent. With regard to the colon, we did not retrieve any relevant publications. In summary, in patients with ulcer disease there is one good reason more to discourage from smoking.
authors.affiliation: Medizinische Klinik, Klinikum Innenstadt, Universität München.
authors.forename: A G
authors.initials: AG
authors.lastname: Klauser
authors.forename: S A
authors.initials: SA
authors.lastname: Müller-Lissner
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology; D001639:Bicarbonates / Q000378:metabolism; D005744:Gastric Acid / Q000378:metabolism*; D005764:Gastroesophageal Reflux / Q000503:physiopathology; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D009130:Muscle, Smooth / Q000503:physiopathology; D010434:Pepsin A / Q000378:metabolism; D010437:Peptic Ulcer / Q000503:physiopathology*; D012636:Secretory Rate / Q000502:physiology; D012907:Smoking / Q000009:adverse effects* / Q000503:physiopathology
chemical_list: D001639:Bicarbonates; D010434:Pepsin A
vernacular_title: Rauchen und gastrointestinale Funktion.