title: Tumor control probability for permanent implants in prostate.
abstract: The tumor control probabilities (TCPs) for 11 transperineal permanent implants of the prostate with 125I seeds have been computed, based on target-specific volume-dose histogram data. Prostate dose-response of this modality is converted from that of external beam therapy based on biologically effective dose derived from the alpha beta model. The calculated TCPs for these transperineal prostate cases are compared with the results of 679 previous retropubic implants, providing interesting insight about these two techniques. Further refinement and validation of this model await long-term followup results of sufficient number of patients.
authors.affiliation: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY.
authors.forename: J N
authors.initials: JN
authors.lastname: Roy
authors.forename: L L
authors.initials: LL
authors.lastname: Anderson
authors.forename: K E
authors.initials: KE
authors.lastname: Wallner
authors.forename: Z
authors.initials: Z
authors.lastname: Fuks
authors.forename: C C
authors.initials: CC
authors.lastname: Ling
mesh_terms: D001918:Brachytherapy; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage
chemical_list: D007457:Iodine Radioisotopes