title: Hallervorden-Spatz disease with bilateral involvement of globus pallidus and substantia nigra: MR demonstration.
abstract: Hallervorden-Spatz disease presents with relentless mental and physical deterioration. Pathologically there is abnormal iron deposition in the globi pallidi, substantia nigra, and red nuclei. A spectrum of abnormal basal ganglia signal intensities have been described on MRI. A pediatric case with low signal intensity in the globi pallidi and substantia nigra is presented.
authors.affiliation: Department of Diagnostic Radiology, Henry Ford Hospital, Detroit, MI 48202.
authors.forename: L
authors.initials: L
authors.lastname: Porter-Grenn
authors.forename: R
authors.initials: R
authors.lastname: Silbergleit
authors.forename: B A
authors.initials: BA
authors.lastname: Mehta
mesh_terms: D002648:Child; D005260:Female; D005917:Globus Pallidus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000175:diagnosis* / Q000473:pathology; D013378:Substantia Nigra / Q000473:pathology*