Acute non-lymphocytic leukemia with t(16;21).
A patient with ANLL FAB subtype M1 was found to possess a t(16;21)(p11;q22) and trisomy 10. The 16;21 translocation has been reported in 12 other cases of ANLL, of various subtypes, and its relationship to the disease profile is discussed.
Nobbs
M C
MC
South Western Regional Cytogenetics Centre, Southmead Hospital, Bristol, U.K.
Chan-Lam
D
D
Howell
R T
RT
Kitchen
C
C
Copplestone
J A
JA
D000328:Adult; D002871:Chromosome Banding; D002879:Chromosomes, Human, Pair 10; D002885:Chromosomes, Human, Pair 16; D002891:Chromosomes, Human, Pair 21; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic; D014314:Trisomy