Hepatocellular carcinoma associated with chronic Schistosoma mansoni infection in a chimpanzee.
Hepatocellular carcinoma associated with chronic Schistosoma mansoni infection in a chimpanzee, estimated to be a 12-year-old and born in West Africa, is reported. The hepatic tumor appeared as a solitary firm nodule, and histological examination revealed well-differentiated hepatocellular carcinoma with a trabecular pattern. Hepatitis B virus and hepatitis C virus infections were excluded by serological testing in that animal. This is the first report of hepatocellular carcinoma in the chimpanzee with schistosomiasis.
Abe
K
K
Department of Pathology, National Institute of Health, Tokyo, Japan.
Kagei
N
N
Teramura
Y
Y
Ejima
H
H
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D002908:Chronic Disease; D005260:Female; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D002679:Pan troglodytes; D012555:Schistosomiasis mansoni / Q000150:complications / Q000473:pathology / Q000662:veterinary*