Comparative efficacy of two- and five-day courses of ceftriaxone for treatment of severe shigellosis in children.
Administration of ceftriaxone for 5 days has been shown to be highly efficient in the treatment of severe shigellosis in children. Our study, involving 40 children, demonstrated that a 2-day course of ceftriaxone was as beneficial as a 5-day course and constituted effective therapy for children with severe shigellosis.
Eidlitz-Marcus
T
T
Department of Pediatrics, Hasharon Hospital, Sackler School of Medicine, Tel Aviv University, Petach Tikvah, Israel.
Cohen
Y H
YH
Nussinovitch
M
M
Elian
I
I
Varsano
I
I
D000293:Adolescent; D002443:Ceftriaxone / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003968:Diarrhea, Infantile / Q000188:drug therapy / Q000382:microbiology; D004305:Dose-Response Relationship, Drug; D004405:Dysentery, Bacillary / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D012763:Shigella flexneri; D012764:Shigella sonnei; D016896:Treatment Outcome
D002443:Ceftriaxone