Dilated cardiomyopathy in haemophiliacs infected with the human immunodeficiency virus.
Infection with the human immunodeficiency virus (HIV) can result in several cardiac abnormalities including dilated cardiomyopathy. These phenomena have been described in people contracting the virus through sexual intercourse, injection drug use and by vertical transmission. We have identified recently two Scottish haemophiliacs who have developed dilated cardiomyopathy in the context of HIV infection acquired through treatment with contaminated factor VIII. The significance of this finding is discussed.
Jacob
A J
AJ
Department of Cardiology, Royal Infirmary, Edinburgh.
Sutherland
G R
GR
Boon
N A
NA
Ludlam
C A
CA
D000293:Adolescent; D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000150:complications* / Q000175:diagnosis; D004452:Echocardiography; D004562:Electrocardiography; D005169:Factor VIII / Q000032:analysis; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000097:blood / Q000150:complications* / Q000276:immunology; D006467:Hemophilia A / Q000097:blood / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
D005169:Factor VIII