title: Effect of serotonin on gastrointestinal electrical activity in the conscious piglet.
abstract: In conscious piglets with electrodes implanted in the wall of the antrum pylori, duodenum, jejunum and ileum, the influence of intravenous infusion of serotonin (5-HT), 4 micrograms/kg/min for 2 hours, on gastrointestinal electrical activity and arterial pressure was examined. 5-HT was without significant influence on antral electrical activity and arterial pressure. In the small intestinal parts 5-HT provoked a shortening of the interval of the migrating myoelectrical complex (MMC) by reducing the duration of phase I and phase II activities, and an increase in propagation velocity. 5-HT also induced an increase in phase III activity. A possible involvement of 5-HT in the initiation and propagation of the MMC is suggested.
authors.affiliation: Laboratory of Veterinary Physiology, University Centre of Antwerp, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Wechsung
authors.forename: A
authors.initials: A
authors.lastname: Houvenaghel
mesh_terms: D000818:Animals; D004576:Electromyography / Q000662:veterinary; D005260:Female; D007262:Infusions, Intravenous / Q000662:veterinary; D007421:Intestine, Small / Q000187:drug effects* / Q000502:physiology; D012701:Serotonin / Q000008:administration & dosage / Q000494:pharmacology*; D013270:Stomach / Q000187:drug effects* / Q000502:physiology; D013552:Swine / Q000502:physiology*
chemical_list: D012701:Serotonin