title: 3-(Alkylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers?
authors.affiliation: Laboratoire de Chimie Pharmaceutique, Université de Liège, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Pirotte
authors.forename: P
authors.initials: P
authors.lastname: de Tullio
authors.forename: P
authors.initials: P
authors.lastname: Lebrun
authors.forename: M H
authors.initials: MH
authors.lastname: Antoine
authors.forename: J
authors.initials: J
authors.lastname: Fontaine
authors.forename: B
authors.initials: B
authors.lastname: Masereel
authors.forename: M
authors.initials: M
authors.lastname: Schynts
authors.forename: L
authors.initials: L
authors.lastname: Dupont
authors.forename: A
authors.initials: A
authors.lastname: Herchuelz
authors.forename: J
authors.initials: J
authors.lastname: Delarge
mesh_terms: D000818:Animals; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism*; D015221:Potassium Channels / Q000187:drug effects*; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D013329:Structure-Activity Relationship; D013829:Thiadiazines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D007328:Insulin; D015221:Potassium Channels; D011725:Pyridines; D013829:Thiadiazines