Azotobacter vinelandii mutS: nucleotide sequence and mutant analysis.
An Azotobacter vinelandii homolog to the Salmonella typhimurium mutS gene was discovered upstream of the fdxA gene. The product of this gene is much more similar to S. typhimurium MutS than either is to the HexA protein of Streptococcus pneumoniae. An A. vinelandii delta mutS mutant strain was shown to have a spontaneous mutation frequency 65-fold greater than that of the wild type.
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Department of Molecular Biology and Biochemistry, University of California, Irvine 92717.
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Iismaa
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Burgess
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D000251:Adenosine Triphosphatases; D000595:Amino Acid Sequence; D016948:Azotobacter vinelandii / Q000235:genetics*; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics*; D004260:DNA Repair; D004268:DNA-Binding Proteins / Q000235:genetics; D029968:Escherichia coli Proteins; D005288:Ferredoxins / Q000235:genetics; D017353:Gene Deletion; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D051719:MutS DNA Mismatch-Binding Protein; D012486:Salmonella typhimurium / Q000235:genetics; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D013296:Streptococcus pneumoniae / Q000235:genetics
D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; D005288:Ferredoxins; C084499:HexA protein, bacteria; D000251:Adenosine Triphosphatases; D051719:MutS DNA Mismatch-Binding Protein; C497175:MutS protein, E coli