Correcting for factors affecting ABR wave V latency.
The latency of auditory brainstem response (ABR) wave V has been shown to be affected by several subject and technical factors. Previous studies have often concluded with a recommendation to account or correct for one or more of these factors when latency is used as a means of detecting retrocochlear dysfunction. This study investigated the effect of subject age, sex, hearing loss and stimulus intensity on ABR wave V latency in a group of 189 clinical subjects in whom retrocochlear disease was effectively excluded. Regression analysis showed that all four factors exerted a significant influence on latency and that hearing loss and intensity were most effectively represented when combined to form a sensation level variable, together with a measure of audiogram slope.
Lightfoot
G R
GR
Department of Clinical Engineering, Royal Liverpool University Hospital.
D000161:Acoustic Stimulation / Q000379:methods; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001300:Audiometry, Evoked Response; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D015834:Cochlear Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D004056:Differential Threshold; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006313:Hearing Loss, Central / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D012001:Hyperacusis; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000175:diagnosis* / Q000503:physiopathology; D011930:Reaction Time; D012044:Regression Analysis; D012737:Sex Factors