title: [Effectiveness of ketanserin in the treatment of light-to-moderate arterial hypertension].
abstract: The above study was undertaken in order to demonstrate the efficacy of ketanserin in mild to moderate essential arterial hypertension. Twenty-two patients, mean age 49.7 yrs., were studied during 36 months. After a 15-day washout period with clinical and instrumental assessment of basal conditions, treatment with 40 mg ketanserin every 12 hrs. was started. Pressure, blood chemistry and instrumental investigation were carried out systematically and showed the hypotensive action of ketanserin as well as a significant (about 12%) rise in HDL-cholesterol.
authors.affiliation: Dipartimento di Medicina Interna, Policlinico S. Matteo, Pavia.
authors.forename: L
authors.initials: L
authors.lastname: Poletti
authors.forename: R
authors.initials: R
authors.lastname: Fogari
authors.forename: M A
authors.initials: MA
authors.lastname: Bressan
authors.forename: M
authors.initials: M
authors.lastname: Poggio
authors.forename: M
authors.initials: M
authors.lastname: Daglio
authors.forename: L
authors.initials: L
authors.lastname: Ripamonti
authors.forename: D
authors.initials: D
authors.lastname: Vlacos
authors.forename: G
authors.initials: G
authors.lastname: Azzaretti
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D008076:Cholesterol, HDL / Q000097:blood / Q000187:drug effects; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007650:Ketanserin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D008076:Cholesterol, HDL; D007650:Ketanserin
vernacular_title: Efficacia della ketanserina nel trattamento dell'ipertensione arteriosa lieve-moderata.