title: [Natural history of viral hepatitis A in Chilean adults: clinical and laboratory aspects].
abstract: In many countries, Hepatitis is mainly due to virus. A. When improving life condition in a given population, initially there is a tendency to increase the number of cases in adults. We report clinical and laboratory findings in 87 adults with acute viral Hepatitis A in Chile. The rate man/woman was 1.55/1. Mean age: 23.8 years. Clinical forms: icteric classical (77.01%), cholestatic (10.34%), anicteric (8.05%), biphasic (2.30%) and fulminant (2.30%). From 87 patients in consult 1, 64 were controlled at day 15 (consult 2) and 35 one year later (consult 3). Laboratory (means): ALT (UI/L): 856.8, 111.6 and 20.8 in consult 1, 2 and 3 respectively. Correlation between values of ALT and AST (p < 0.0001). Mean total bilirubin (mg%): 6.6, 2.5 and 0.8 respectively. The evolution of Hepatitis A was favorable with a rapid decrease of clinical signs and normalization of laboratory values within the 3 first weeks of disease.
authors.affiliation: Instituto de Medicina, Facultad de Medicina, Universidad Austral de Chile.
authors.forename: H
authors.initials: H
authors.lastname: Ibarra
authors.forename: S
authors.initials: S
authors.lastname: Riedemann
authors.forename: G
authors.initials: G
authors.lastname: Froesner
authors.forename: G
authors.initials: G
authors.lastname: Reinhardt
authors.forename: J C
authors.initials: JC
authors.lastname: Gómez
authors.forename: A
authors.initials: A
authors.lastname: Cornejo
authors.forename: C
authors.initials: C
authors.lastname: Toledo
authors.forename: N
authors.initials: N
authors.lastname: Soto
authors.forename: M
authors.initials: M
authors.lastname: Ruiz
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002677:Chile / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006506:Hepatitis A / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012737:Sex Factors; D012959:Socioeconomic Factors; D013997:Time Factors
chemical_list: D007075:Immunoglobulin M
vernacular_title: Historia natural de la hepatitis viral A en adultos en Chile: clínica y laboratorio.