title: [A clinical study of intravenous captopril in heart failure].
abstract: A clinical study of intravenous captopril was performed in 10 patients with mild heart failure and 20 with severe heart failure. The results indicated that intravenous captopril may rapidly reduce cardiac preload and afterload, increase cardiac output, inhibit renin system activity and decrease plasma level of catecholamine. A short period of treatment with intravenous captopril may produce a rapid symptomatic improvement in patients with acute or severe heart failure. There was a good tolerance with the therapy.
authors.affiliation: Department of Internal Medicine, Tongji Hospital, Tongji Medical University, Wuhan.
authors.forename: H
authors.initials: H
authors.lastname: Wu
authors.forename: H Y
authors.initials: HY
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000804:Angiotensin II / Q000097:blood; D001806:Blood Urea Nitrogen; D002216:Captopril / Q000627:therapeutic use*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged
chemical_list: D000804:Angiotensin II; D002216:Captopril