Aggressive angiomyxoma of the pelvioperineal region. Immunohistological and ultrastructural study of seven cases.
We describe seven cases of aggressive angiomyxoma of the pelvioperineal region. In three cases, we observed immunohistochemical signs of myoid differentiation in the tumor cells. In one of these cases, we could confirm the myoid differentiation at the ultrastructural level. The other four cases were devoid of this differentiation. We further discuss the relationship of aggressive angiomyxoma to the recently described angiomyofibroblastoma of the vulva.
Skálová
A
A
Sikls Department of Pathology, Medical Faculty, Charles University, Pilsen, Czech Republic.
Michal
M
M
Husek
K
K
Zámecník
M
M
Leivo
I
I
D000199:Actins / Q000032:analysis; D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D003094:Collagen / Q000032:analysis; D003893:Desmin / Q000032:analysis; D005109:Extracellular Matrix / Q000648:ultrastructure; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D007797:Laminin / Q000032:analysis; D008854:Microscopy, Electron; D008875:Middle Aged; D009130:Muscle, Smooth / Q000473:pathology; D009232:Myxoma / Q000098:blood supply / Q000473:pathology* / Q000648:ultrastructure; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D010386:Pelvic Neoplasms / Q000098:blood supply / Q000473:pathology* / Q000648:ultrastructure; D014846:Vulvar Neoplasms / Q000098:blood supply / Q000473:pathology* / Q000648:ultrastructure
D000199:Actins; D003893:Desmin; D007797:Laminin; D003094:Collagen