Sex linked valvular dysplasia.
A family is described in which three males have been affected by congenital valvular dysplasia of one or more heart valves, in one case leading to neonatal death. The pedigree is consistent with sex linked inheritance.
Newbury-Ecob
R A
RA
Department of Clinical Genetics, City Hospital, Nottingham, UK.
Zuccollo
J M
JM
Rutter
N
N
Young
I D
ID
D000328:Adult; D005808:Genes, Recessive; D008040:Genetic Linkage; D006330:Heart Defects, Congenital / Q000235:genetics*; D006349:Heart Valve Diseases / Q000151:congenital* / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009154:Mutation; D012729:Sex Chromosome Aberrations; D014694:Ventricular Outflow Obstruction / Q000151:congenital / Q000235:genetics; D014960:X Chromosome