title: Hydrogen grafted polymer surfaces: interaction and morphology of platelets.
abstract: Besides the quantification of platelet adhesion, the morphology of adherent platelets on a polymer surface seems to be important as far as thrombogenicity is concerned. It is suggested that such events usually take place on a layer of adsorbed proteins on the surface of the blood. In the present study, we observed the morphological variation of adherent calf platelets (in vitro under static conditions) on bare and hydrogel-grafted Angioflex sheets. Electron micrographs indicate the extent of deformation of the Angioflex sheets varying with modified substrates as compared to the bare sheets.
authors.affiliation: Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram, India.
authors.forename: P R
authors.initials: PR
authors.lastname: Hari
authors.forename: B
authors.initials: B
authors.lastname: Ajithkumar
authors.forename: C P
authors.initials: CP
authors.lastname: Sharma
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001792:Blood Platelets / Q000648:ultrastructure; D002417:Cattle; D008855:Microscopy, Electron, Scanning; D010973:Platelet Adhesiveness; D011102:Polyhydroxyethyl Methacrylate / Q000032:analysis; D011140:Polyurethanes; D012826:Silicone Elastomers; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D011140:Polyurethanes; D012826:Silicone Elastomers; D011102:Polyhydroxyethyl Methacrylate; C084425:Angioflex