Localization of 15 cosmids on human chromosome 22 by fluorescence in situ hybridization.
Fluorescence in situ hybridization has been used in a cytogenetic analysis to map 15 cosmids on human chromosome 22. Thirteen cosmids were localized on the long arm of chromosome 22 (22q) while two other probes displayed a hybridization signal on 22p and the short arm of the acrocentric chromosomes of groups D and G. The regional assignment of these new chromosome markers will improve the mapping of chromosome 22; they can be used to detect numerical and structural aberrations of this chromosome involved in numerous pathologies.
Lévy
N
N
CNRS URA 1158, Laboratoire de Cytogénétique et Génétique Oncologiques, Institut Gustave-Roussy, Villejuif, France.
Lamour
V
V
Danglot
G
G
Slim
R
R
Lipinski
M
M
Bernheim
A
A
D002874:Chromosome Mapping; D002892:Chromosomes, Human, Pair 22; D003360:Cosmids / Q000235:genetics*; D015342:DNA Probes / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D017404:In Situ Hybridization, Fluorescence
D015342:DNA Probes; D005819:Genetic Markers