Control of vertebrate gastrulation: inducing signals and responding genes.
Recently, genes with similar expression patterns in the early gastrulae of several different vertebrate species have been identified. The remarkable conservation of these expression patterns suggests that fundamental similarities exist within the vertebrates at remarkably early stages. It has yet to be established exactly how these genes are activated in the correct spatial patterns and what their functions might be.
Beddington
R S
RS
Laboratory of Mammalian Development, National Institute for Medical Research, Mill Hill, London, UK.
Smith
J C
JC
D000818:Animals; D004627:Embryonic Induction / Q000502:physiology; D005775:Gastrula / Q000502:physiology*; D005786:Gene Expression Regulation; D008648:Mesoderm; D015398:Signal Transduction; D014714:Vertebrates / Q000196:embryology* / Q000235:genetics