Effect of aging on respiratory skeletal muscles.
Although it has been recognized that limb skeletal muscles undergo changes during aging, it has been unclear to what extent age-related changes occur in respiratory muscles. This article reviews the structural organization of human skeletal muscles, including those of the respiratory system. Evidence that changes do occur in the structure and function of these muscles in elderly individuals is presented. The potential clinical significance of aging on respiratory muscle strength and endurance is discussed.
Tolep
K
K
Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.
Kelsen
S G
SG
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D000818:Animals; D005081:Exercise Therapy; D005121:Extremities; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D009132:Muscles / Q000033:anatomy & histology / Q000502:physiology; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000033:anatomy & histology* / Q000502:physiology*