title: Hypertrophic cardiomyopathy in a dog.
abstract: A 12-year-old spayed Corgi with heart failure did not respond to conventional medical therapy for congestive cardiomyopathy (furosemide, 2.5 mg/kg of body weight, IV, q 8 h; captopril 1 mg/kg, PO, q 8 h). Cardiac ultrasonography subsequently revealed a hypertrophic left ventricle and interventricular septum. Because a causative agent could not be identified, a diagnosis of primary hypertrophic cardiomyopathy was made. Administration of diltiazem (1.25 mg/kg, PO, q 12 h) resulted in sustained clinical improvement for several weeks. Complete cardiac evaluation, including echocardiography, was essential in determining the correct treatment for this dog.
authors.affiliation: Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PEI, Canada.
authors.forename: C A
authors.initials: CA
authors.lastname: Marks
mesh_terms: D000818:Animals; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D004110:Diltiazem / Q000627:therapeutic use*; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004285:Dogs; D004359:Drug Therapy, Combination; D004452:Echocardiography / Q000662:veterinary; D005260:Female; D005665:Furosemide / Q000627:therapeutic use*
chemical_list: D005665:Furosemide; D004110:Diltiazem