title: Surgical relief of acute airway obstruction due to primary tuberculosis.
abstract: Primary pulmonary tuberculosis in children remains a leading cause of mortality and morbidity in developing countries. Thirteen children requiring urgent thoracotomy for relief of acute respiratory distress resulting from critical major airway narrowing caused by enlarged tuberculous mediastinal lymph nodes were admitted to two hospitals over a 4-year period. Ages ranged from 2 months to 10 years. The condition of each patient had deteriorated despite appropriate antituberculosis therapy and an oral corticosteroid. At operation, the enlarged tuberculous subcarinal or paratracheal lymph nodes or both were decompressed. Surgical complications included a bronchial tear and a pulmonary artery laceration. Additional procedures included a right upper lobectomy, two pneumonectomies, plication of a hemidiaphragm, and mobilization of two muscle flaps. Postoperatively all children showed dramatic improvement. The trachea to main bronchi diameter ratio improved by 49.1% on the left and 44.9% on the right in the immediate postoperative period. In children with respiratory distress produced by compression of the main bronchi between enlarged subcarinal and paratracheal lymph nodes, surgical decompression of the lymph nodes is indicated if there is no marked initial response to appropriate medical therapy. At operation, lymph nodes should be decompressed only by incision and curettage. Attempts at lymph node excision are associated with increased complications.
authors.affiliation: Department of Cardiothoracic Surgery, University of Cape Town, South Africa.
authors.forename: M G
authors.initials: MG
authors.lastname: Worthington
authors.forename: J G
authors.initials: JG
authors.lastname: Brink
authors.forename: J A
authors.initials: JA
authors.lastname: Odell
authors.forename: J
authors.initials: J
authors.lastname: Buckels
authors.forename: M K
authors.initials: MK
authors.lastname: de Groot
authors.forename: M
authors.initials: M
authors.lastname: Klein
authors.forename: A J
authors.initials: AJ
authors.lastname: Gunning
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D000402:Airway Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011182:Postoperative Care; D011183:Postoperative Complications; D011859:Radiography; D012086:Reoperation; D012189:Retrospective Studies; D013908:Thoracotomy; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents