title: Dynamic breath-hold multiplanar spoiled gradient-recalled MR imaging with gadolinium enhancement for differentiating hepatic hemangiomas from malignancies at 1.5 T.
abstract: OBJECTIVE
  To compare the enhancement patterns of focal liver lesions at dynamic breath-hold gadolinium-enhanced multiplanar spoiled gradient-recalled (SPGR) magnetic resonance (MR) imaging with T2 relaxation times in the differentiation of liver hemangiomas from malignancies.
  
  
  METHODS
  Forty-seven patients with focal liver lesions underwent MR imaging with spin-echo and gadolinium-enhanced multiplanar SPGR techniques. T2 relaxation times and enhancement patterns were compared for accuracy in liver lesion characterization.
  
  
  RESULTS
  Enhancement patterns allowed better characterization of liver lesions than did T2 relaxation times. Only specific patterns of contrast enhancement indicated a hemangioma. Although 18 of the 33 malignancies and 10 of the 12 hemangiomas showed progressive centripetal hyperintense enhancement, only hemangiomas filled in with hyperintense peripheral nodules. Malignancies often filled in with hyperintense thick rinds.
  
  
  CONCLUSIONS
  Gadolinium-enhanced multiplanar SPGR imaging allows more accurate characterization of liver lesions than does T2 relaxation time.
authors.affiliation: Department of Radiology, Stanford University School of Medicine, CA 94305-5488.
authors.forename: W S
authors.initials: WS
authors.lastname: Whitney
authors.forename: R J
authors.initials: RJ
authors.lastname: Herfkens
authors.forename: R B
authors.initials: RB
authors.lastname: Jeffrey
authors.forename: C H
authors.initials: CH
authors.lastname: McDonnell
authors.forename: K C
authors.initials: KC
authors.lastname: Li
authors.forename: W J
authors.initials: WJ
authors.lastname: Van Dalsem
authors.forename: R N
authors.initials: RN
authors.lastname: Low
authors.forename: I R
authors.initials: IR
authors.lastname: Francis
authors.forename: J F
authors.initials: JF
authors.lastname: Dabatin
authors.forename: G M
authors.initials: GM
authors.lastname: Glazer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis; D003287:Contrast Media; D003937:Diagnosis, Differential; D004338:Drug Combinations; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006391:Hemangioma / Q000175:diagnosis*; D006571:Heterocyclic Compounds; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008536:Meglumine; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D004338:Drug Combinations; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C062402:gadoteridol; D008536:Meglumine; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA