Dietary factors and survival from breast cancer.
The association between self-reported intake of various dietary factors at diagnosis and survival from breast cancer was studied in a population-based cohort of breast cancer patients in Adelaide, South Australia. These patients had been recruited between 1982 and 1984 into a case-control study of diet and incident breast cancer. Of the 451 patients recruited originally, 412 were followed for a median interval of 5.5 years. There were decreases in the risk of death from breast cancer ranging from 25 to 40% at all levels of energy and protein intake above the baseline, whereas for fat intake there was a 40% increase in risk at the uppermost quintile level. There was also some reduction in risk at the upper levels of intake of beta-carotene and vitamin C. However, there were no dose-dependent variations in risk of death by level of intake for any of the dietary factors studied, and most of the variation in risk that was observed was relatively insubstantial.
Rohan
T E
TE
National Cancer Institute of Canada (NCIC) Epidemiology Unit, University of Toronto, Ontario.
Hiller
J E
JE
McMichael
A J
AJ
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D001943:Breast Neoplasms / Q000453:epidemiology / Q000378:metabolism / Q000401:mortality*; D016022:Case-Control Studies; D015331:Cohort Studies; D004032:Diet; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage* / Q000009:adverse effects; D004043:Dietary Fiber; D004044:Dietary Proteins / Q000008:administration & dosage; D002149:Energy Intake; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D016016:Proportional Hazards Models; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D012307:Risk Factors; D013021:South Australia / Q000453:epidemiology; D015996:Survival Rate
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D004044:Dietary Proteins; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone