title: [Detection and analysis of cryoglobulins: comparative study of a population of patients and one of healthy controls].
abstract: During an 11-month period, 270 cryoglobulins were identified in 735 sera from patients versus 34 in 82 sera from apparently healthy blood donors. Western-blot analysis of the cryoglobulins was performed and cryoglobulin protein content was determined using a colorimetric assay. Comparison of findings in the two groups suggested that a substantial proportion of cryoglobulins identified in the sera of patients are quantitatively and qualitatively indistinguishable from cryoglobulins identified in healthy controls.
authors.affiliation: Laboratoire d'Immunologie, Faculté de Pharmacie, Clermont-Ferrand, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Romaszko
authors.forename: A
authors.initials: A
authors.lastname: Tridon
authors.forename: P
authors.initials: P
authors.lastname: Jouanel
authors.forename: E
authors.initials: E
authors.lastname: Subtil
authors.forename: P
authors.initials: P
authors.lastname: Dibet
authors.forename: G
authors.initials: G
authors.lastname: Betail
mesh_terms: D001424:Bacterial Infections / Q000097:blood; D003450:Cryoglobulins / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D007122:Immunoelectrophoresis; D007674:Kidney Diseases / Q000097:blood; D012016:Reference Values; D012216:Rheumatic Diseases / Q000097:blood; D012871:Skin Diseases / Q000097:blood
chemical_list: D003450:Cryoglobulins
vernacular_title: Détection et analyse des cryoglobulines: étude comparative d'une population de malades et d'une population de témoins sains.