Radioisotopic labels for blood cell survival studies: a review.
The different methods of labeling blood cells, in particular erythrocytes and platelets, for survival studies are reviewed. Besides the technical information about these procedures, attention is also paid to the indications of blood cell survival studies, the effective dose equivalent involved and the interpretation of the resulting data. In the final section the possibilities created by dual-labeling procedures are discussed.
de Vries
R A
RA
Hospital Gelderse Vallei, Department of Internal Medicine, Bennekom, The Netherlands.
de Bruin
M
M
Marx
J J
JJ
Van de Wiel
A
A
D000818:Animals; D001773:Blood Cells / Q000502:physiology; D001792:Blood Platelets / Q000502:physiology; D002470:Cell Survival; D004912:Erythrocytes / Q000502:physiology; D006801:Humans; D007553:Isotope Labeling / Q000379:methods*