[Glucose-6-phosphate dehydrogenase deficiency in erythrocytes observed in two cases].
In two male patients the deficiency of G-6-PD in erythrocytes became manifested in 27th year of age with severe hemolytic crisis. In the first case hemolysis appeared after three days of heavy alcohol drinking. There was no evident relation between alcohol and hemolysis. In the second patient (an Iraqi Student) suffering from diabetes since adolescence, hemolysis was provoked by respiratory tract infection, antiinflammatory drugs and concomitant ketosis. Pneumonia, renal insufficiency and acute pancreatitis complicated the course of illness. The patient required a consecutive erythrocyte concentrate transfusions. Aplastic crisis was treated with folic acid.
Przybyłowski
J
J
Kliniki Chorób Wewnetrznych Instytutu Medycyny Klinicznej, Krakowie.
Kłos
M
M
Kisiel
E
E
Mierzwa-Slefarska
H
H
D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000201:enzymology*; D005492:Folic Acid / Q000627:therapeutic use; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood / Q000209:etiology / Q000628:therapy; D006801:Humans; D007662:Ketosis / Q000150:complications; D008297:Male; D012141:Respiratory Tract Infections / Q000150:complications
D005492:Folic Acid
Niedobór dehydrogenazy glukozo-6-fosforanu krwinek czerwonych w świetle obserwowanych dwóch przypadków.