title: DNA repair in the variable platyfish (Xiphophorus variatus) irradiated in vivo with ultraviolet B light.
abstract: Dark- and light-dependent DNA repair processes were studied in vivo in the variable platyfish, Xiphophorus variatus. Excision (dark) repair of the (6-4) photoproduct was more efficient than that of the cyclobutane dimer with approximately 70% of the (6-4) photoproducts removed by 24 h post-UVB radiation compared to approximately 30% of the cyclobutane dimers. Exposure to photoreactivating light resulted in rapid loss of most (> 90%) of the cyclobutane dimers and increased excision repair of the (6-4) photoproduct. Preexposure to photoreactivating light 8 h prior to UVB radiation increased the rate of photoreactivation two-fold.
authors.affiliation: University of Texas M.D. Anderson Cancer Center, Science Park/Research Division, Smithville 78957.
authors.forename: D L
authors.initials: DL
authors.lastname: Mitchell
authors.forename: J T
authors.initials: JT
authors.lastname: Scoggins
authors.forename: D C
authors.initials: DC
authors.lastname: Morizot
mesh_terms: D000818:Animals; D003532:Cyprinodontiformes / Q000235:genetics*; D004260:DNA Repair / Q000528:radiation effects*; D011740:Pyrimidine Dimers / Q000737:chemistry; D014466:Ultraviolet Rays
chemical_list: D011740:Pyrimidine Dimers