Immunohistochemical demonstration of neuron specific antigen, HPC-1 in the enteric nervous system of the guinea-pig distal colon.
The HPC-1 antigen is a newly identified neuron specific membrane protein in the central nervous system. The HPC-1 antigen was revealed similarity to epimorphin. The presence of HPC-1 antigen in the enteric nervous system of guinea-pig distal colon was immunohistochemically demonstrated using the antibody against the HPC-1. Immunohistochemical study clearly revealed the topography and structure of the enteric nervous system of the guinea-pig distal colon. HPC-1 was present only in the nervous system and entirely distributed. HPC-1 antigen is present at the surfaces of ganglion cells, but not in the cytoplasm.
Nagahama
M
M
Institute for Developmental Research, Aichi, Japan.
Tsutsui
Y
Y
Kuwahara
A
A
Akagawa
K
K
D000818:Animals; D000954:Antigens, Surface / Q000276:immunology*; D003106:Colon / Q000276:immunology / Q000294:innervation*; D017615:Enteric Nervous System / Q000276:immunology / Q000502:physiology*; D006168:Guinea Pigs; D007150:Immunohistochemistry; D008297:Male; D009419:Nerve Tissue Proteins / Q000276:immunology*; D009457:Neuroglia / Q000276:immunology; D050827:Syntaxin 1
D000954:Antigens, Surface; D009419:Nerve Tissue Proteins; D050827:Syntaxin 1