Simple sequence repeat length polymorphisms mapped to rat chromosome 11.
Two genes and two anonymous DNA loci were mapped to rat chromosome 11 using F2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) inbred rats. These four loci formed a single linkage group covering 21.5 cM with the following map order: somatostatin (SST)-D11N161-D11N18-cell surface protein (MOX2). These four loci were typed by PCR-based simple sequence repeat (SSR) length polymorphism detection. For each marker four to seven different alleles were detected using a panel of 13 inbred rat strains (F344/N, LEW/N, BN/SsN, BUF/N, LER/N, MR/N, MNR/N, LOU/MN, ACI/N, WBB1/N, WBB2/N, SHR/N, WKY/N). Comparative gene mapping analysis suggests syntenic conservation between rat chromosome 11 and mouse Chromosome 16.
Du
Y
Y
Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD.
Remmers
E F
EF
Goldmuntz
E A
EA
Zha
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H
Mathern
P
P
Crofford
L J
LJ
Wilder
R L
RL
D000483:Alleles; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D017931:DNA Primers / Q000737:chemistry; D008040:Genetic Linkage; D005819:Genetic Markers; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D051381:Rats; D011916:Rats, Inbred F344 / Q000235:genetics*; D011917:Rats, Inbred Lew / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid
D017931:DNA Primers; D005819:Genetic Markers