title: The human D11S554 locus: four distinct families of repeat pattern alleles at one locus.
abstract: We have sequenced amplified products of 44 short tandem repeat alleles at the human D11S554 locus. The sequences revealed four distinct, but related, families of consensus repeat patterns. Six alleles deviated from the consensus patterns. Alleles differed in size by as little as one base pair, and precise sizing is required for analysis of alleles at this highly polymorphic locus. The evolution of alleles at the D11S554 locus and related short tandem repeat loci is discussed.
authors.affiliation: Central Research and Support Establishment, Forensic Science Service, Aldermaston, Berkshire, UK.
authors.forename: M
authors.initials: M
authors.lastname: Adams
authors.forename: A
authors.initials: A
authors.lastname: Urquhart
authors.forename: C
authors.initials: C
authors.lastname: Kimpton
authors.forename: P
authors.initials: P
authors.lastname: Gill
mesh_terms: D000483:Alleles; D001483:Base Sequence; D002880:Chromosomes, Human, Pair 11; D016384:Consensus Sequence; D004247:DNA / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D005819:Genetic Markers; D004247:DNA