Isocladosporin, a biologically active isomer of cladosporin from Cladosporium cladosporioides.
Extraction of the fungus Cladosporium cladosporioides yielded the known isocoumarin, cladosporin [1], and a new compound. This metabolite, which inhibited the growth of etiolated wheat coleoptiles slightly more than did cladosporin, was characterized as a diastereoisomer of cladosporin at C-14 and was named isocladosporin [2].
Jacyno
J M
JM
College of Pharmacy, Ohio Northern University, Ada 45810.
Harwood
J S
JS
Cutler
H G
HG
Lee
M K
MK
D002963:Cladosporium / Q000737:chemistry* / Q000378:metabolism; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D049934:Isocoumarins; D013058:Mass Spectrometry; D008968:Molecular Conformation; D009183:Mycotoxins / Q000737:chemistry* / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism; D014908:Triticum / Q000187:drug effects / Q000254:growth & development*
D003374:Coumarins; D049934:Isocoumarins; D009183:Mycotoxins; C000488:cladosporin