title: Laser-assisted enterocystoplasty in rats.
abstract: The employment of laser welds to anastomose bowel to bladder in urological surgery has never been described. Using rats, we compared laser-assisted enterocystoplasty (LAE) with conventional sutured enterocystoplasty (CSE). A "patch" ileocystoplasty was performed using distal ileum. Operative time, intraluminal bursting pressure and histologic changes were evaluated. Operative time was 38% less in the LAE (p < 0.001). No statistically significant differences in bursting pressure between LAE and CSE groups was demonstrated (p = 0.654) in rats sacrificed 2 weeks postoperatively. Histologic findings in the laser-assisted enterocystoplasties included early loose granulation tissue and later organization of the granulation tissue with significant collagen deposition. In our preliminary study, laser welding of bowel within the urinary stream was safe, efficacious and rapid and resulted in a mechanically comparable surgical outcome.
authors.affiliation: Department of Urology, University of Miami School of Medicine, Florida.
authors.forename: P E
authors.initials: PE
authors.lastname: Perito
authors.forename: M
authors.initials: M
authors.lastname: Carter
authors.forename: F
authors.initials: F
authors.lastname: Civantos
authors.forename: S
authors.initials: S
authors.lastname: Hart
authors.forename: C M
authors.initials: CM
authors.lastname: Lynne
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D007082:Ileum / Q000601:surgery; D053685:Laser Therapy; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013536:Suture Techniques; D001743:Urinary Bladder / Q000601:surgery*; D014547:Urinary Diversion / Q000379:methods*; D016476:Urinary Reservoirs, Continent