title: [Fetal chromosome abnormalities diagnosed by chorionic villi sampling].
abstract: Chorionic villus sampling was performed for chromosome analysis in 387 cases during a 4-year-period. In 115 cases transcervical while in 272 cases transabdominal sampling was carried out. Chromosomal abnormalities were found in 25 cases (6.4%). Autosomal trisomies occurred in 17 cases, structural anomalies in 2 cases and sex chromosomal aberrations in 6 cases. The pregnancy was terminated in 19 cases because of chromosome abnormality, in 5 further cases because of X-linked disease and male fetus. After transcervical sampling spontaneous abortion occurred in 7 cases (5.8%), while after transabdominal sampling in 8 cases (2.8%). The authors prefer in their practice the early transabdominal CVS, which can be performed safety already at the end of the first trimester.
authors.affiliation: Petz Aladár Megyei Kórház Györ, Szülészeti és Nögyógyászati Osztály.
authors.forename: S
authors.initials: S
authors.lastname: Gardó
authors.forename: K
authors.initials: K
authors.lastname: Bajnóczky
authors.forename: M
authors.initials: M
authors.lastname: Nagy
authors.forename: S
authors.initials: S
authors.lastname: Nagy
mesh_terms: D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations / Q000175:diagnosis* / Q000235:genetics; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis; D012729:Sex Chromosome Aberrations / Q000175:diagnosis / Q000235:genetics; D014314:Trisomy / Q000175:diagnosis / Q000235:genetics; D014960:X Chromosome
vernacular_title: Chorionbolyhokból diagnosztizált magzati kromoszóma-rendellenességek.