Cytokines as mediators of organ graft rejection and tolerance.
The analysis of cytokines following organ transplantation continues to flourish as a major area of investigation for transplant biologists. Over the past year many papers have reported the use of both molecular and antibody-based tools to dissect the expression of cytokines during graft rejection in both experimental and clinical transplantation. Further, how the expression of cytokines is altered during the induction of tolerance has been investigated by several groups.
Dallman
M J
MJ
University of Oxford, Nuffield Department of Surgery, John Radcliffe Hospital, Headington, UK.
D000818:Animals; D016207:Cytokines / Q000096:biosynthesis / Q000276:immunology*; D006084:Graft Rejection / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D015850:Interleukin-6 / Q000096:biosynthesis / Q000276:immunology; D016377:Organ Transplantation; D016133:Polymerase Chain Reaction; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis / Q000276:immunology
D016207:Cytokines; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha