title: Zinc metallopeptidases: active site structure and design of selective and mixed inhibitors: new approaches in the search for analgesics and anti-hypertensives.
authors.affiliation: Département de Pharmacochimie Moléculaire et Structurale, U266 INSERM-URA D 1500 CNRS, Faculté de Pharmacie, Paris, France.
authors.forename: B P
authors.initials: BP
authors.lastname: Roques
mesh_terms: D000595:Amino Acid Sequence; D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001665:Binding Sites; D015195:Drug Design; D006801:Humans; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors*; D008969:Molecular Sequence Data; D015260:Neprilysin / Q000037:antagonists & inhibitors*; D015032:Zinc / Q000378:metabolism
chemical_list: D000700:Analgesics; D000959:Antihypertensive Agents; D008666:Metalloendopeptidases; D015260:Neprilysin; D015032:Zinc