The effect of taurine on the incorporation of thymidine by chick B cells.
1. This study was conducted to determine the effect of extracellular taurine on chick B cell proliferation as measured by the incorporation of [3H] thymidine. 2. B cells were cultured in RPMI-1640 media containing bacterial lipopolysaccharide and either 0 or 100 microM taurine. 3. Thymidine incorporation was significantly increased in the presence of 100 microM extracellular taurine. 4. These results suggest a role for taurine in the chick B cell proliferation process.
Porter
D W
DW
West Virginia University, College of Agriculture and Forestry, Division of Animal and Veterinary Science, Morgantown 26506.
Kaczmarczyk
W
W
Martin
W G
WG
D000818:Animals; D001402:B-Lymphocytes / Q000187:drug effects*; D002455:Cell Division / Q000502:physiology; D002478:Cells, Cultured; D002645:Chickens / Q000378:metabolism*; D013654:Taurine / Q000494:pharmacology*; D013936:Thymidine / Q000378:metabolism*
D013654:Taurine; D013936:Thymidine