Evaluation of rapid urease test for detection of Helicobacter pylori in gastric biopsy specimens.
Using 80 gastric biopsy specimens from patients with various gastroduodenal diseases, the isolation rate of H. pylori and urease activity of the biopsy specimens were examined. The sensitivity and specificity of the rapid urease test was 84.6% and 75.9%, respectively, for the cultivation of H. pylori. The mean number of H. pylori detected in urease-positive and negative biopsy specimens was 10(6.1 +/- 0.9) and 10(4.5 +/- 1.2) cfu/g specimens, respectively.
Kamiya
S
S
Department of Infectious Diseases, Tokai University, Isehara, Japan.
Taniguchi
I
I
Yamamoto
T
T
Shirai
T
T
Harasawa
S
S
Miwa
T
T
Ozawa
A
A
D000328:Adult; D000368:Aged; D001706:Biopsy; D004378:Duodenal Diseases / Q000175:diagnosis / Q000382:microbiology*; D004942:Esophagitis, Peptic / Q000175:diagnosis / Q000382:microbiology; D005260:Female; D005753:Gastric Mucosa / Q000201:enzymology / Q000473:pathology; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000201:enzymology / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013272:Stomach Diseases / Q000175:diagnosis / Q000382:microbiology*; D014510:Urease / Q000378:metabolism*
D014510:Urease