[Isolation and structure elucidation of qianhucoumarin A].
Seven compounds were isolated from the traditional Chinese Medicine Qianhu, roots of Peucedanum praeruptorum Dunn. Their structures were identified as psoralen (II), 5-methoxypsoralen (III), 8-methoxypsoralen (IV), pteryxin (V), peucedanocoumarin II (VI), beta-sitosterol (VII) and qianhucoumarin A (VIII) by physico-chemical constants and spectral analyses (UV, IR, 1HNMR, 13CNMR, EIMS). VIII is a new compound with the structure of 3'(R)-hydroxy-4'(R)-tigloyloxy-3',4'-dihydroseslin. Its absolute configurations were determined by chemical correlation with known compounds. II, III, IV and VII were first isolated from this plant.
Kong
L Y
LY
Research Department of Natural Medicine, Shenyang College of Pharmacy.
Pei
Y H
YH
Li
X
X
Zhu
T R
TR
Okuyama
T
T
D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D011564:Furocoumarins / Q000302:isolation & purification; D015394:Molecular Structure
D003374:Coumarins; D004365:Drugs, Chinese Herbal; D011564:Furocoumarins; C084440:qianhucoumarin A