title: [A case of postoperative chylothorax successfully treated by chemical pleurodesis with OK-432].
abstract: Recently, cases of postoperative chylothorax have increased concomitantly with the increase in number of aggressive thoracic surgery. Chylothorax was complicated on the 6 th postoperative day in a 69-year-old male who underwent right lower lobectomy with mediastinal lymph node dissection for adenocarcinoma of the lung. After the leaking point from thoracic duct was confirmed by lymphangiography and chest CT, OK-432 1.5 KE was instilled into the intrapleural space through a intrathoracic tube. By this procedure, the chylous fistulas were completely cured. Application of OK-432, even in such a small dose as 1.5 KE, appeared very useful for the treatment of postoperative chylothorax.
authors.affiliation: First Department of Surgery, Kagoshima University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: N
authors.initials: N
authors.lastname: Mitani
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
authors.forename: Y
authors.initials: Y
authors.lastname: Horikawa
authors.forename: H
authors.initials: H
authors.lastname: Nishijima
authors.forename: T
authors.initials: T
authors.lastname: Shimotakahara
authors.forename: H
authors.initials: H
authors.lastname: Shimazu
authors.forename: T
authors.initials: T
authors.lastname: Oyama
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000368:Aged; D002916:Chylothorax / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007322:Instillation, Drug; D008175:Lung Neoplasms / Q000601:surgery; D008297:Male; D010844:Picibanil / Q000008:administration & dosage / Q000627:therapeutic use*; D010994:Pleura; D011013:Pneumonectomy / Q000009:adverse effects*
chemical_list: D010844:Picibanil