title: Ganglioglioma presenting as a vascular lesion in a 10-year-old boy. Case report.
abstract: The authors present the case of a 10-year-old boy admitted for evaluation of a generalized seizure and a history of headaches. Computerized tomography (CT) and gadolinium-enhanced magnetic resonance (MR) imaging demonstrated a large nonhomogeneous contrast-enhancing mass of the left frontal lobe, with a large cystic component. Cerebral angiography revealed the lesion to be highly vascular and fed entirely by the internal carotid artery system. The patient underwent craniotomy and the lesion was completely removed. Neuropathological study revealed that the tumor was a ganglioglioma. On review of the literature, it was found that gangliogliomas often present in the second and third decade, are known to have cystic components, and are contrast-enhancing on CT and MR imaging; however, they are classically known to be avascular on angiography. This case of a markedly vascular ganglioglioma emphasizes that these tumors should be included in the differential diagnosis of vascular supratentorial lesions.
authors.affiliation: Department of Neurosurgery, Montreal Children's Hospital, McGill University, Quebec, Canada.
authors.forename: G H
authors.initials: GH
authors.lastname: Baltuch
authors.forename: J P
authors.initials: JP
authors.lastname: Farmer
authors.forename: K
authors.initials: K
authors.lastname: Meagher-Villemure
authors.forename: A M
authors.initials: AM
authors.lastname: O'Gorman
authors.forename: J L
authors.initials: JL
authors.lastname: Montes
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000175:diagnosis*; D002648:Child; D003937:Diagnosis, Differential; D005625:Frontal Lobe; D018303:Ganglioglioma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed