title: An unusual retinal pigment epitheliopathy endemic to the island of Guam.
abstract: An unusual retinal pigment epitheliopathy resembling ophthalmomyiasis interna posterior (OMI) is endemic to Guam. Sixteen percent of a sample of the indigenous population were found to have the retinopathy. Fifty-two percent of a group of individuals suffering from amyotrophic lateral sclerosis/Parkinsonism-dementia complex (ALS/PDC) were found to have the same retinopathy. Although the retinal appearance is similar to that caused by a subretinal parasite, a definite etiology has not been identified. Three case reports are presented as samples of the clinical presentation of the condition.
authors.affiliation: Micronesian Health Study, University of Guam, Mangilao.
authors.forename: S D
authors.initials: SD
authors.lastname: Hanlon
authors.forename: J C
authors.initials: JC
authors.lastname: Steele
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001927:Brain Diseases / Q000453:epidemiology; D015822:Eye Infections, Parasitic / Q000453:epidemiology; D005260:Female; D005654:Fundus Oculi; D006141:Guam / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009198:Myiasis / Q000453:epidemiology; D010857:Pigment Epithelium of Eye / Q000469:parasitology / Q000473:pathology*; D012164:Retinal Diseases / Q000453:epidemiology* / Q000469:parasitology