[Detection and analysis of cryoglobulins: comparative study of a population of patients and one of healthy controls].
During an 11-month period, 270 cryoglobulins were identified in 735 sera from patients versus 34 in 82 sera from apparently healthy blood donors. Western-blot analysis of the cryoglobulins was performed and cryoglobulin protein content was determined using a colorimetric assay. Comparison of findings in the two groups suggested that a substantial proportion of cryoglobulins identified in the sera of patients are quantitatively and qualitatively indistinguishable from cryoglobulins identified in healthy controls.
Romaszko
J P
JP
Laboratoire d'Immunologie, Faculté de Pharmacie, Clermont-Ferrand, France.
Tridon
A
A
Jouanel
P
P
Subtil
E
E
Dibet
P
P
Betail
G
G
D001424:Bacterial Infections / Q000097:blood; D003450:Cryoglobulins / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D007122:Immunoelectrophoresis; D007674:Kidney Diseases / Q000097:blood; D012016:Reference Values; D012216:Rheumatic Diseases / Q000097:blood; D012871:Skin Diseases / Q000097:blood
D003450:Cryoglobulins
Détection et analyse des cryoglobulines: étude comparative d'une population de malades et d'une population de témoins sains.