Antiepileptic drugs for the treatment of panic disorder.
Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder. We review the theoretical basis and available clinical data supporting the use of these agents in panic disorder.
Keck
P E
PE
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559.
McElroy
S L
SL
Tugrul
K C
KC
Bennett
J A
JA
Smith
J M
JM
D000927:Anticonvulsants / Q000627:therapeutic use*; D002220:Carbamazepine / Q000627:therapeutic use; D002998:Clonazepam / Q000627:therapeutic use; D006801:Humans; D016584:Panic Disorder / Q000188:drug therapy* / Q000523:psychology; D014635:Valproic Acid / Q000627:therapeutic use
D000927:Anticonvulsants; D002220:Carbamazepine; D002998:Clonazepam; D014635:Valproic Acid