Successful fibrinolytic therapy using tissue plasminogen activator in acute renal failure due to acute thrombosis of bilateral renal arteries.
A 46-year-old housewife with regurgitation of mitral valve developed acute renal failure due to acute thrombosis of bilateral renal arteries after cardiac catheterization. A regional fibrinolytic therapy using transarterial infusion of tissue plasminogen activator (t-PA) was performed at 8 h after the onset, and was successful. She could be taken off hemodialysis 2 weeks after the fibrinolytic therapy, and could be successfully operated on with mitral valve replacement 7 months after that. Three years after mitral valve replacement, her serum creatinine was 148 mumol/l. This is the longest follow-up case after regional transarterial fibrinolysis of acute thrombosis of renal artery using t-PA, and this therapy is a safe and good one for acute thrombosis of renal artery.
Takeda
M
M
Department of Urology, Niigata University School of Medicine, Japan.
Katayama
Y
Y
Takahashi
H
H
Saito
K
K
Tsutsui
T
T
Komeyama
T
T
D000208:Acute Disease; D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008875:Middle Aged; D012074:Remission Induction; D012078:Renal Artery Obstruction / Q000150:complications* / Q000473:pathology; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000150:complications* / Q000473:pathology; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
D010959:Tissue Plasminogen Activator