Identification of T-like and B-like lymphocyte subsets in sea star Asterias rubens by monoclonal antibodies to human leukocytes.
The axial organ of sea star Asterias rubens is a primitive immune organ. The total cell population was fractionated into two populations: adherent (B-like) and non-adherent cells (T-like) to nylon wool. These two cell subsets were previously defined as functionally acting as mammals T and B cells. In the present report, we pointed out that these T and B-like cells can be identified using mouse to human monoclonal antibodies. Reproducible results were obtained with anti-CD7 monoclonal antibody which detects the T-like cell subset and with anti-CD14 antibody that characterizes the B-like population.
Leclerc
M
M
Immunologie des Invertébrés, UER Sciences, Université d'Orléans, France.
Arneodo
V J
VJ
Legac
E
E
Bajelan
M
M
Vaugier
G L
GL
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D016175:B-Lymphocyte Subsets / Q000276:immunology*; D003429:Cross Reactions; D005434:Flow Cytometry; D006801:Humans; D013215:Starfish / Q000166:cytology / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*
D000911:Antibodies, Monoclonal