A case control study of selenium in cancer.
As selenium has been shown to be a risk modifier of cancer at several sites in a case-control approach, selenium nutriture was studied in oral and oesophageal cancer patients. The mean selenium level in oral cancer patients was 102.6 ng/ml and in oesophageal cancer 103.3 ng/ml, while in the matched controls it was 117.5 and 116.2 ng/ml respectively. Relative risk estimates were 3.16 (P < 0.02) and 16.0 (P < 0.01) in oral and oesophageal cancer patients respectively. The risk appears to increase with selenium levels lower than 115 ng/ml.
Krishnaswamy
K
K
Food & Drug Toxicology Research Centre, National Institute of Nutrition, Hyderabad.
Prasad
M P
MP
Krishna
T P
TP
Pasricha
S
S
D016022:Case-Control Studies; D004032:Diet; D004938:Esophageal Neoplasms / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000097:blood*; D016017:Odds Ratio; D012307:Risk Factors; D012643:Selenium / Q000008:administration & dosage / Q000097:blood*
D012643:Selenium