title: [Extended resections in bronchial cancer: complications and late results].
abstract: From 1982 through April 1992, 192 patients underwent extended resection for non-small cell carcinoma of the lung (NSCLC) invading the chest wall (n = 52) or the mediastinum (n = 140). Complete resection of the tumor was possible in 81 (58%) patients with invasion of mediastinum and in 34 (65%) patients with invasion of the chest wall. The operative mortality was 9%, respiratory complications causing most of the postoperative morbidity and mortality. Incomplete resection was associated with poor prognosis. The mean survival of these patients was 10 month. The 5 year actuarial survival rate of patients having curative resection was 20%. In these patients the presence of lymphatic metastases significantly reduced survival, with a 3 year actuarial survival rate of 40% of patients with No disease, and 30% or 5% for those with N1 or N2 disease, respectively. In conclusion, extended resection for advanced NSCLC offers a significant chance for long-term survival in the absence of N2 lymphatic metastases. In the presence of N2 metastases and poor overall prognosis however, reasonable palliation is the primary goal of surgical management.
authors.affiliation: Chirurgische Klinik und Poliklinik, Klinikum Grosshadern, Ludwig-Maximilians-Universität München.
authors.forename: H
authors.initials: H
authors.lastname: Dienemann
authors.forename: H
authors.initials: H
authors.lastname: Hoffmann
authors.forename: A
authors.initials: A
authors.lastname: Mewes
authors.forename: C
authors.initials: C
authors.lastname: Müller
authors.forename: F W
authors.initials: FW
authors.lastname: Schildberg
mesh_terms: D002283:Carcinoma, Bronchogenic / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000379:methods; D011183:Postoperative Complications / Q000401:mortality; D015996:Survival Rate; D013908:Thoracotomy / Q000379:methods*
vernacular_title: Erweiterte Resektionen bei Bronchialkarzinom: Komplikationen und Spätergebnisse.