The manufacture and molecular characterization of phosphorothioate deoxynucleotides for use as antisense therapeutics in human clinical trials.
Bergot
B J
BJ
Lynx Therapeutics, Inc., Foster City, CA 94404.
Foy
M
M
Hansen
C
C
Fearon
K
K
Frediani
J
J
Hirschbein
B
B
D017321:Clinical Trials, Phase I as Topic; D016373:DNA, Antisense / Q000138:chemical synthesis* / Q000235:genetics / Q000627:therapeutic use; D003854:Deoxyribonucleotides / Q000737:chemistry* / Q000235:genetics / Q000627:therapeutic use; D005786:Gene Expression Regulation; D016158:Genes, p53; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D013873:Thionucleotides / Q000138:chemical synthesis* / Q000235:genetics / Q000627:therapeutic use
D016373:DNA, Antisense; D003854:Deoxyribonucleotides; D013873:Thionucleotides