title: Successful delivery following myocardial ischemia during the second trimester of pregnancy.
abstract: Acute myocardial infarction during pregnancy is considered to be associated with approximately 50% mortality of both mother and fetus. However, there are not enough data regarding the role of acute myocardial ischemia. We present a 36-year-old, pregnant, white female who was admitted twice at 18 and 20 weeks of gestation with acute myocardial ischemia. Cardiac catheterization revealed 70-80% stenosis of the mid left anterior descending artery (LAD) with normal antegrade flow and very good retrograde filling of the LAD from distal collaterals of the right coronary artery. Therefore, due to angiographic suggestion of protected LAD territory, we recommended medical therapy and scheduled a vaginal delivery that was successfully completed without cardiovascular complications. A stress thallium test performed 6 months later was normal, supporting our clinical judgment. In conclusion, every case of a pregnant woman with coronary insufficiency should be treated according to individual coronary anatomy and blood supply to the territory of the diseased artery, and should not be based on the old data in the literature. The decision for revascularization prior to delivery versus medical therapy, or Caesarean section versus natural delivery, should be made by a team of a cardiologist and an obstetrician.
authors.affiliation: Heart Institute, Kaplan Hospital, Rehovot, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Shalev
authors.forename: H
authors.initials: H
authors.lastname: Ben-Hur
authors.forename: Z
authors.initials: Z
authors.lastname: Hagay
authors.forename: I
authors.initials: I
authors.lastname: Blickstein
authors.forename: M
authors.initials: M
authors.lastname: Epstein
authors.forename: O
authors.initials: O
authors.lastname: Ayzenberg
authors.forename: A
authors.initials: A
authors.lastname: Gelven
authors.forename: A
authors.initials: A
authors.lastname: Caspi
mesh_terms: D000208:Acute Disease; D000328:Adult; D001262:Atenolol / Q000627:therapeutic use; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007548:Isosorbide Dinitrate; D007751:Labor, Induced; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000188:drug therapy*; D009543:Nifedipine / Q000627:therapeutic use; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000188:drug therapy*; D011256:Pregnancy Outcome
chemical_list: D001262:Atenolol; D006493:Heparin; D009543:Nifedipine; D007548:Isosorbide Dinitrate