Cataracts in Morquio syndrome (mucopolysaccharidosis IV A).
Three siblings with Morquio syndrome (mucopolysaccharidosis IV A) are described. In addition to the characteristic dwarfism with skeletal deformities, odontoid anomalies, hearing loss and corneal clouding, the authors found almost identical lens opacities in all three patients. Lenticular opacities have not previously been described in patients with Morquio's syndrome IV A.
Olsen
H
H
Department of Ophthalmology, Aarhus University Hospital, Denmark.
Baggesen
K
K
Sjolie
A K
AK
D000293:Adolescent; D002386:Cataract / Q000150:complications / Q000175:diagnosis*; D002478:Cells, Cultured; D002648:Child; D002811:Chondroitinsulfatases / Q000378:metabolism; D003241:Consanguinity; D005260:Female; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D007908:Lens, Crystalline / Q000473:pathology*; D008297:Male; D009085:Mucopolysaccharidosis IV / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D010375:Pedigree
D002811:Chondroitinsulfatases