title: Adaptation of Pseudomonas putida S12 to high concentrations of styrene and other organic solvents.
abstract: Pseudomonas putida S12 could adapt to grow on styrene in a two-phase styrene-water system. Acetate was toxic for P. putida S12, but cells were similarly able to adapt to higher acetate concentrations. Only by using these acetate-adapted cells was growth observed in the presence of supersaturating concentrations of toxic nonmetabolizable solvents such as toluene.
authors.affiliation: Department of Food Science, Agricultural University, Wageningen, The Netherlands.
authors.forename: F J
authors.initials: FJ
authors.lastname: Weber
authors.forename: L P
authors.initials: LP
authors.lastname: Ooijkaas
authors.forename: R M
authors.initials: RM
authors.lastname: Schemen
authors.forename: S
authors.initials: S
authors.lastname: Hartmans
authors.forename: J A
authors.initials: JA
authors.lastname: de Bont
mesh_terms: D000085:Acetates / Q000378:metabolism / Q000494:pharmacology; D019342:Acetic Acid; D000222:Adaptation, Physiological; D016958:Pseudomonas putida / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D012997:Solvents / Q000378:metabolism* / Q000494:pharmacology; D020058:Styrene; D013343:Styrenes / Q000378:metabolism* / Q000494:pharmacology; D014050:Toluene / Q000378:metabolism / Q000494:pharmacology
chemical_list: D000085:Acetates; D012997:Solvents; D013343:Styrenes; D014050:Toluene; D020058:Styrene; D019342:Acetic Acid