Population dynamics of human malaria parasites.
Highly sensitive detection and identification of the four Plasmodium species infecting man, and the characterization of P. falciparum isolates, have been achieved by PCR amplification. The results obtained from field and laboratory studies are described. The significance of these observations to the design and interpretation of epidemiological investigations is discussed.
Snounou
G
G
Division of Parasitology, National Institute for Medical Research, Mill Hill, London U.K.
D000818:Animals; D016054:DNA, Protozoan / Q000235:genetics; D005828:Genetics, Population; D006169:Guinea-Bissau; D006801:Humans; D008288:Malaria / Q000469:parasitology* / Q000517:prevention & control; D010961:Plasmodium / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010963:Plasmodium falciparum / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011157:Population Dynamics; D012680:Sensitivity and Specificity; D013045:Species Specificity; D013785:Thailand
D016054:DNA, Protozoan