title: Efferent synapse mechanisms in chick hair cells.
abstract: Electrical stimulation of the efferent fiber to the hair cell is known to suppress peripheral auditory function. In isolated hair cells from the chick, acetylcholine (ACh) generated membrane hyperpolarization when a puff was applied at concentrations from 1 microM to 5 mM. Ionophoretic application of ACh generated a membrane hyperpolarization with a rapid time course. This is due to the increase of K conductance and is accompanied by the rise of the [Ca]i.
authors.affiliation: Department of Physiology, Faculty of Medicine, University of Kyoto, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ohmori
mesh_terms: D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D002118:Calcium / Q000502:physiology; D002645:Chickens; D004525:Efferent Pathways / Q000502:physiology*; D006198:Hair Cells, Auditory / Q000502:physiology*; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission
chemical_list: D000109:Acetylcholine; D002118:Calcium