[Treatment of menorrhagia with tranexamic acid. A clinical trial of an underestimated problem in general practice].
44 women with heavy menstrual bleeding participated in a six months randomised, double blind, cross over clinical trial. The objective was to use simple methods to study whether treatment of menorrhagia with tranexamic acid has an effect that can be detected by the women themselves. The effect was evaluated by means of diaries and a visual analog scale. The bleeding during each period of treatment was compared with the bleeding during untreated periods. Bleeding during the different periods of treatment was also compared directly. The results indicate that tranexamic acid was more effective than placebo. This difference was not disclosed, however, in the laboratory data. After the study, 75% of the women wished to continue treatment with tranexamic acid.
Drøsdal
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D000328:Adult; D004311:Double-Blind Method; D005194:Family Practice; D005260:Female; D006801:Humans; D008595:Menorrhagia / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged; D014148:Tranexamic Acid / Q000009:adverse effects / Q000627:therapeutic use*
D014148:Tranexamic Acid
Behandling av menoragi med tranexamsyre. Klinisk studie av et undervurdert problem i allmennprakis.