title: Differentiation of sugar assimilation characteristics and colony phenotypes in pathogenic and commensal oral candidal isolates.
abstract: A comparison of sugar assimilation patterns has been made using 72 oral candidal isolates recovered from diseased and non-diseased patients. Significant differences were demonstrated between isolates recovered from diseased versus healthy mouths. In addition, significant changes in colony phenotype (switch frequency and morphologic predominance) were found to relate to predictive data generated from carbon source utilization data. These results suggest that biochemical properties and colony phenotypic characteristics may hold promise in predicting the behavior of oral candidal isolates in disease.
authors.affiliation: United States Army Dental Corp., Fort Bliss, Texas.
authors.forename: J H
authors.initials: JH
authors.lastname: Hellstein
authors.forename: P G
authors.initials: PG
authors.lastname: Fotos
authors.forename: S S
authors.initials: SS
authors.lastname: Law
authors.forename: M
authors.initials: M
authors.lastname: Kovacevic
authors.forename: K C
authors.initials: KC
authors.lastname: Carriere
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002176:Candida albicans / Q000145:classification / Q000166:cytology / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D002180:Candidiasis, Oral / Q000382:microbiology; D050260:Carbohydrate Metabolism; D002648:Child; D002675:Child, Preschool; D004269:DNA, Bacterial / Q000235:genetics; D005260:Female; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D007223:Infant; D007785:Lactose / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D009059:Mouth Diseases / Q000382:microbiology*; D010641:Phenotype
chemical_list: D004269:DNA, Bacterial; D007785:Lactose