Mixed segregation and recombination of chromosomes and YACs during single-division meiosis in spo13 strains of Saccharomyces cerevisiae.
Diploid yeast strains, homozygous for the mutation spo13, undergo a single-division meiosis and form dyads (two spores held together in one ascus). Dyad analysis of spo13/spo13 strains with centromere-linked markers on five different chromosomes and on a pair of human DNA YACs shows that: (a) in spo13 meiosis, chromosomes undergo mixed segregation, namely some chromosomes segregate reductionally whereas others, in the same cell, segregate equationally; (b) different chromosomes exhibit different segregation tendencies; (c) recombination between homologous chromosomes might not determine that a bivalent undergoes reductional rather than equational segregation.
Hugerat
Y
Y
Department of Genetics, Hebrew University of Jerusalem, Israel.
Simchen
G
G
D002455:Cell Division; D002503:Centromere / Q000648:ultrastructure; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D015825:Chromosomes, Fungal / Q000648:ultrastructure*; D005785:Gene Conversion; D005800:Genes, Fungal; D005819:Genetic Markers; D005838:Genotype; D008540:Meiosis; D009154:Mutation; D011995:Recombination, Genetic; D015183:Restriction Mapping; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics*
D005819:Genetic Markers