Vaginal occlusion induced by cancer therapy.
Two adolescent girls with acquired vaginal occlusion and resultant hematometracolpos are presented. Both are long-term survivors of childhood malignancies, who prior to multiagent chemotherapy and pelvic irradiation had normal uteri by imaging. Both were amenorrheic post therapy. Routine follow-up computed tomography (CT) scans to monitor their malignancies demonstrated unexpected cystic pelvic masses, subsequently diagnosed as hematometracolpos.
Kaste
S C
SC
Department of Diagnostic Imaging, St. Jude Children's Research Hospital, University of Tennessee, Memphis 38105.
Gronemeyer
S A
SA
Muram
D
D
D000293:Adolescent; D000568:Amenorrhea / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006409:Hematometra / Q000209:etiology*; D006801:Humans; D007512:Ischium; D009369:Neoplasms / Q000628:therapy*; D010388:Pelvis; D011878:Radiotherapy / Q000009:adverse effects*; D018232:Rhabdomyosarcoma, Alveolar / Q000628:therapy; D012512:Sarcoma, Ewing / Q000628:therapy; D014057:Tomography, X-Ray Computed; D014621:Vagina / Q000000981:diagnostic imaging / Q000473:pathology* / Q000528:radiation effects