title: [Invasive Haemophilus influenzae type B infections in infancy (1981-1990)].
abstract: We report the epidemiology of invasive Haemophilus influenzae type B infections. The study is based on 58 children and was carried out during the years from 1981 to 1990. Sixty-three percent of the patients had meningitis, 10.3% had arthritis, 10.3% had epiglottitis, 8.6% had cellulitis and 6.9% had pneumonia. Thirteen percent of the cases were children who were less than 6 months old, 34.4% were less than 12 months old, 70.6% were less than 24 months of age and 93% were less than 4 years old. Among the latter, 90% of the children with epiglottis or pneumonia were 24 months or older compared with 16% of the patients with meningitis, arthritis or cellulitis (p < 0.001). Sixty-three percent of the isolated strains of Haemophilus influenzae type B were resistant to ampicillin and 19.2% of the strains were resistant to ampicillin and chloramphenicol.
authors.affiliation: Sección de Infecciosos, Hospital Infantil Miguel Servet, Zaragoza.
authors.forename: F
authors.initials: F
authors.lastname: de Juan Martín
authors.forename: C
authors.initials: C
authors.lastname: Campos Calleja
authors.forename: M
authors.initials: M
authors.lastname: Bustillo Alonso
authors.forename: I
authors.initials: I
authors.lastname: Baldovín Ballesteros
authors.forename: E
authors.initials: E
authors.lastname: Bello Andrés
authors.forename: L
authors.initials: L
authors.lastname: Elviro Mayoral
mesh_terms: D000367:Age Factors; D000667:Ampicillin / Q000494:pharmacology; D001168:Arthritis / Q000453:epidemiology / Q000382:microbiology; D002481:Cellulitis / Q000453:epidemiology / Q000382:microbiology; D002675:Child, Preschool; D002701:Chloramphenicol / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004826:Epiglottitis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006192:Haemophilus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D006193:Haemophilus influenzae / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D008583:Meningitis, Haemophilus / Q000175:diagnosis / Q000453:epidemiology; D011014:Pneumonia / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D012703:Serotyping; D013030:Spain / Q000453:epidemiology
chemical_list: D002701:Chloramphenicol; D000667:Ampicillin
vernacular_title: Infecciones invasivas por Haemophilus influenzae tipo B en la infancia (1981-1990).