title: Wound healing following demineralization of resected root ends in periradicular surgery.
abstract: The objective of this study was to determine the effect of demineralization of resected root ends on the temporal and qualitative healing of the dentoalveolar (apical attachment apparatus) and alveolar (osseous) tissues in the excisional wound site created during periradicular surgery. Root end resections to orthograde gutta-percha obturations were performed on the mandibular premolars of six mongrel dogs. Twenty-four experimental root ends were demineralized by citric acid burnishing of the resected surfaces. The remaining 24 standard treatment root ends were not demineralized. Microscopic evaluations at postsurgical intervals from 4 to 45 days revealed that the demineralized root ends were associated with more rapid and complete healing than the nondemineralized root ends. It is proposed that demineralization enhances cementogenesis, the key to dentoalveolar healing, by removing the smear layer barrier and exposing the organic component (collagen fibrils) of resected cementum and dentin.
authors.affiliation: Baylor College of Dentistry, Dallas, TX 75246.
authors.forename: K R
authors.initials: KR
authors.lastname: Craig
authors.forename: J W
authors.initials: JW
authors.lastname: Harrison
mesh_terms: D000134:Acid Etching, Dental; D000818:Animals; D025021:Cementogenesis; D003648:Decalcification Technique; D003739:Dental Cementum / Q000503:physiopathology; D004285:Dogs; D008137:Longitudinal Studies; D010486:Periapical Tissue / Q000503:physiopathology*; D010513:Periodontal Ligament / Q000503:physiopathology; D016369:Smear Layer; D013997:Time Factors; D017001:Tooth Demineralization; D014092:Tooth Root / Q000503:physiopathology / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology*