title: Cerebral arteriovenous malformations in The Netherlands Antilles. High prevalence of hereditary hemorrhagic telangiectasia-related single and multiple cerebral arteriovenous malformations.
abstract: Seventeen patients with symptomatic cerebral arteriovenous malformations (AVMs) were diagnosed between 1980 and 1990 in the Leeward Islands of the Netherlands Antilles. Five patients had multiple AVMs. The annual incidence of symptomatic AVMs was 1.1/100,000. The mean age of presentation was 35 years. In 6 patients cerebral AVMs were associated with hereditary hemorrhagic telangiectasia (HHT); 4 of these patients had multiple AVMs. We conclude that HHT is frequently encountered in Netherlands Antillians with symptomatic and multiple cerebral AVMs.
authors.affiliation: Department of Internal Medicine, St. Elisabeth Hospital, Curaçao, Netherlands Antilles.
authors.forename: G A
authors.initials: GA
authors.lastname: Jessurun
authors.forename: D J
authors.initials: DJ
authors.lastname: Kamphuis
authors.forename: F H
authors.initials: FH
authors.lastname: van der Zande
authors.forename: J C
authors.initials: JC
authors.lastname: Nossent
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002533:Cerebral Angiography; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015994:Incidence; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009427:Netherlands Antilles / Q000453:epidemiology; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D014057:Tomography, X-Ray Computed