title: Auditory brainstem responses recorded at fast stimulation rates using maximum length sequences.
abstract: There are now commercially available systems which can provide maximum length sequence averaging techniques. This study examines the effects on auditory brainstem response amplitude and latency of using such a system and stimulating at rates from 9 to 1000 clicks/s. As expected there is considerable adaptation of the response such that at 1000 clicks/s wave V amplitude is only approximately 8% of its low stimulation rate value. As the stimulation rate is increased so the test time taken to obtain a response of the same signal-to-noise ratio as a conventional recording decreases. This process continues up to a maximum click rate of about 200 clicks/s. Thereafter, the response adapts so rapidly that further increases of rate lead to a worsening of performance. Thus, the optimum stimulation rate appears to be of the order of 200 clicks/s and this can give a speed improvement by a factor of approximately 2.8 over conventional recordings taken at 9 or 10 clicks/s.
authors.affiliation: MRC Institute of Hearing Research, Royal South Hants Hospital, Southampton, UK.
authors.forename: A R
authors.initials: AR
authors.lastname: Thornton
authors.forename: A
authors.initials: A
authors.lastname: Slaven
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D001300:Audiometry, Evoked Response / Q000379:methods*; D001309:Auditory Threshold / Q000502:physiology; D004569:Electroencephalography / Q000379:methods; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D006801:Humans; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors