title: Isolation of an immunosuppressive lectin from Phaseolus vulgaris L. cv Cacahuate using stroma.
abstract: An immunosuppressive lectin was isolated from seed of Phaseolus vulgaris cv Cacahuate using physically entrapped stroma. The lectin was found to be a 94 kDa tetrameric protein. When 50 micrograms, of this lectin were administered intraperitoneally 2 days before the immunization with sheep red blood cells, humoral response against the immunogen was completely inhibited. Other properties of the protein are discussed.
authors.affiliation: Center of Biological Research, La Paz, México.
authors.forename: F
authors.initials: F
authors.lastname: Vargas-Albores
authors.forename: J
authors.initials: J
authors.lastname: Hernández
authors.forename: F
authors.initials: F
authors.lastname: Córdoba
authors.forename: E
authors.initials: E
authors.lastname: Zenteno
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002241:Carbohydrates / Q000032:analysis; D002417:Cattle; D004492:Edetic Acid / Q000494:pharmacology; D004912:Erythrocytes / Q000276:immunology; D007887:Fabaceae; D006041:Goats; D006168:Guinea Pigs; D006384:Hemagglutination; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents; D046911:Macromolecular Substances; D051379:Mice; D008970:Molecular Weight; D010527:Perissodactyla; D010835:Phytohemagglutinins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D037121:Plant Lectins; D010946:Plants, Medicinal; D011817:Rabbits; D051381:Rats; D012639:Seeds / Q000737:chemistry*; D012756:Sheep; D013696:Temperature
chemical_list: D000596:Amino Acids; D002241:Carbohydrates; D007166:Immunosuppressive Agents; D046911:Macromolecular Substances; D010835:Phytohemagglutinins; D037121:Plant Lectins; D004492:Edetic Acid