title: Bone regeneration guided by resorbable collagen membranes in rabbits: a pilot study.
abstract: Artificial cross-shaped intrabony defects were created in the mandibles of 12 rabbits and the cavities covered with Type I highly cross-linked resorbable collagen membranes for 30 days. Similar cavities were prepared in three control animals and left uncovered for the same time period. Morphological and analytical data were obtained by means of light microscopy, scanning electron microscopy, and x-ray energy-dispersive spectrometry. After the experimental period, the membrane covered cavities were completely filled with regenerated bone. In the control specimens, the artificial cavities were occupied by fibrous connective tissue.
authors.affiliation: Dental School, University G. D'Annunzio, Chieti, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Colangelo
authors.forename: A
authors.initials: A
authors.lastname: Piattelli
authors.forename: S
authors.initials: S
authors.lastname: Barrucci
authors.forename: P
authors.initials: P
authors.lastname: Trisi
authors.forename: G
authors.initials: G
authors.lastname: Formisano
authors.forename: S
authors.initials: S
authors.lastname: Caiazza
mesh_terms: D000818:Animals; D001673:Biodegradation, Environmental; D001861:Bone Regeneration; D003094:Collagen; D005069:Evaluation Studies as Topic; D005260:Female; D048091:Guided Tissue Regeneration; D008297:Male; D008334:Mandible; D008566:Membranes; D008855:Microscopy, Electron, Scanning; D010865:Pilot Projects; D011817:Rabbits; D014945:Wound Healing
chemical_list: D003094:Collagen