title: Neoadjuvant (induction) chemotherapy in advanced bladder carcinoma.
abstract: Traditional approaches for the treatment of locally advanced bladder tumours may not be sufficient enough. Neoadjuvant chemotherapy, a new modality, may be beneficial by enhancing the local and systemic control of the disease. The background of this new modality and early results of various trials are discussed.
authors.affiliation: Department of Urology, Marmara University School of Medicine, Istanbul, Turkey.
authors.forename: L
authors.initials: L
authors.lastname: Türkeri
authors.forename: Y
authors.initials: Y
authors.lastname: Ilker
authors.forename: F
authors.initials: F
authors.lastname: Simşek
authors.forename: A
authors.initials: A
authors.lastname: Akdaş
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D015996:Survival Rate; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D014747:Vinblastine / Q000008:administration & dosage
chemical_list: D009944:Organoplatinum Compounds; C055423:didimethylsulfoxide dichloroplatinum(II); D014747:Vinblastine; D004317:Doxorubicin; D003520:Cyclophosphamide; D008727:Methotrexate