title: Effect of ethanol on hippocampal neurons depends on their behavioural specialization.
abstract: Acute effect of ethanol on hippocampal neurons was studied during food acquisition behaviour in seven rabbits. The rabbits were taught to acquire food from a feeder by pressing a pedal on the same side of the cage. The behaviourally specialized units (L units related to newly learned behaviour and M units related to behaviour formed before learning, e.g. certain movements) were comparable with the 'place' (projectional pyramidal and granular cells) and 'displace' (non-pyramidal interneurons) units of the current classification. The same direction of ethanol effects was found as for the limbic cortex; the number of certain kinds of L units decreased and that of M units increased but there was no significant change in the relative number of L and M units as a whole. The background frequency of L units decreased, but the frequency within activations increased. The results confirm our earlier findings on the most marked depressive effect of ethanol on L units and show that it is the behavioural specialization, not the morphological unit type, which is a major determinant of the ethanol influence.
authors.affiliation: Institute of Psychology, Russian Academy of Sciences, Moscow.
authors.lastname: Alexandrov YuI
authors.lastname: Grinchenko YuV
authors.forename: S
authors.initials: S
authors.lastname: Laukka
authors.forename: T
authors.initials: T
authors.lastname: Järvilehto
authors.forename: V N
authors.initials: VN
authors.lastname: Maz
authors.forename: A V
authors.initials: AV
authors.lastname: Korpusova
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004576:Electromyography / Q000187:drug effects; D004594:Electrophysiology; D000431:Ethanol / Q000494:pharmacology*; D005247:Feeding Behavior / Q000187:drug effects; D006624:Hippocampus / Q000166:cytology* / Q000187:drug effects; D008297:Male; D009474:Neurons / Q000187:drug effects*; D051381:Rats
chemical_list: D000431:Ethanol