[Umbilical colonization in normal newborns. A comparative study of 4 methods for umbilical antisepsis].
We report the results of a prospective study in which the effectiveness of 70% alcohol (A), mercurochrome (M), a solution of alcohol and mercurochrome (AM) and 1% chlorhexidine (C) as umbilical antiseptics was tested on 311 normal newborn infants. Similar results were obtained by using A, M, or AM; however, when C was used umbilical colonization was significantly reduced as compared to when the other three antiseptic agents were used. The umbilical cords that had been scrubbed with A, M or AM were detached by the 8th day after birth, whereas those treated with C took 14 days to fall off. The use of chlorhexidine resulted in a marked increase in pure cultures positive for Gram negative bacteria (Proteus spp. and Pseudomonas spp.) which was not the case with the other three antiseptics tested.
Perapoch López
J
J
Servicio de Neonatología, Hospital Universitario Materno-Infantil Vall d'Hebrón, Universitat Autonoma de Barcelona.
Salcedo Abizanda
S
S
Gallart Catalá
A
A
Peguero Monforte
G
G
Casellas Caro
M
M
Barroso Pérez
C
C
Fernández Pérez
F
F
Rodríguez Garrido
V
V
D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D000985:Antisepsis / Q000379:methods*; D001419:Bacteria / Q000302:isolation & purification; D006801:Humans; D007231:Infant, Newborn; D011446:Prospective Studies; D012016:Reference Values; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D014472:Umbilicus / Q000382:microbiology*
D000891:Anti-Infective Agents, Local
Colonización umbilical en recién nacidos normales. Estudio comparativo de cuatro métodos de antisepsia umbilical.