title: Synthesis and biological activity of some methoctramine-related tetraamines bearing a 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-one moiety as antimuscarinics: a second generation of highly selective M2 muscarinic receptor antagonists.
authors.affiliation: Department of Pharmaceutical Sciences, University of Bologna, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Melchiorre
authors.forename: M L
authors.initials: ML
authors.lastname: Bolognesi
authors.forename: A
authors.initials: A
authors.lastname: Chiarini
authors.forename: A
authors.initials: A
authors.lastname: Minarini
authors.forename: S
authors.initials: S
authors.lastname: Spampinato
mesh_terms: D000818:Animals; D001569:Benzodiazepines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D003959:Diamines / Q000737:chemistry* / Q000494:pharmacology; D006168:Guinea Pigs; D015394:Molecular Structure; D018727:Muscarinic Antagonists; D051381:Rats; D011976:Receptors, Muscarinic / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D003959:Diamines; D018727:Muscarinic Antagonists; D011976:Receptors, Muscarinic; D001569:Benzodiazepines; C084480:tripitramine; C054938:methoctramine