title: Prilocaine: an old anesthetic agent and a new ophthalmic procedure.
abstract: We present a new local anesthetic technique for ophthalmic surgery that reduces the risks associated with retrobulbar and peribulbar anesthesia. This method uses topical proparacaine plus 1.5 mL of prilocaine (3%) with felypressin injected into the subconjunctival (sub-Tenon's) space. Of 5210 consecutive adult patients in whom the technique was used, all demonstrated adequate analgesia. Sixty-three (1.2%) of the eyes required supplemental analgesia, provided by a single injection of prilocaine (0.5 mL). Ecchymosis and subconjunctival hemorrhage developed in 63 (1.2%) of the eyes. There were no instances of ptosis.
authors.affiliation: Refractive Microsurgery Center, Belo Horizonte, Brazil.
authors.forename: E T
authors.initials: ET
authors.lastname: Coelho
authors.forename: E B
authors.initials: EB
authors.lastname: Gomes
authors.forename: H S
authors.initials: HS
authors.lastname: Martins
authors.forename: B
authors.initials: B
authors.lastname: de Sousa
mesh_terms: D000328:Adult; D000368:Aged; D000698:Analgesia; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage; D003228:Conjunctiva; D005128:Eye Diseases / Q000601:surgery*; D005133:Eye Movements / Q000187:drug effects; D005259:Felypressin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007267:Injections; D008875:Middle Aged; D011318:Prilocaine / Q000008:administration & dosage* / Q000009:adverse effects; D011430:Propoxycaine / Q000008:administration & dosage
chemical_list: D000779:Anesthetics, Local; D011318:Prilocaine; D005259:Felypressin; C005717:proxymetacaine; D011430:Propoxycaine