title: Ocular siderosis.
abstract: The authors report their experience in the management of 8 patients with ocular siderosis due to a retained intraocular foreign body (IOFB). All patients were male, aged between 19 and 39 years. Seven had a definite history of trauma; 3 had presented at the time of injury to a casualty department, and the diagnosis had been missed. The interval between injury and diagnosis ranged from 2 to 24 months. IOFB removal was performed in 7 patients: through a sclerotomy and magnet or foreign body forceps in 4 eyes and via a pars plana vitrectomy and intraocular foreign body forceps in 3 eyes. Cataract extraction was performed in 4 patients. Histological examination of specimens removed at the time of surgery showed iron deposition in the conjunctiva, anterior lens capsule and pars plana. Transmission electron microscope X-ray microanalysis showed that iron was contained in siderosomes, intracytoplasmic membrane-bound dense bodies. Final visual acuity was 6/12 or better in 6 patients and reduced to light perception in the remaining 2 due to proliferative vitreoretinopathy.
authors.affiliation: Birmingham and Midland Eye Hospital, UK.
authors.forename: M
authors.initials: M
authors.lastname: Hope-Ross
authors.forename: G J
authors.initials: GJ
authors.lastname: Mahon
authors.forename: P B
authors.initials: PB
authors.lastname: Johnston
mesh_terms: D000328:Adult; D002924:Ciliary Body / Q000648:ultrastructure; D004577:Electron Probe Microanalysis; D005128:Eye Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005129:Eye Foreign Bodies / Q000150:complications*; D015807:Eye Injuries, Penetrating / Q000150:complications*; D006801:Humans; D007501:Iron; D008297:Male; D008854:Microscopy, Electron; D012806:Siderosis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D007501:Iron