Effect of indigenous drugs on glucuronoglycan metabolism in diabetic hypertensive rabbits.
Development of hypertension further exaggerated the deranged level of total glucuronoglycan (GAG), different fractions of GAG, activities of synthetic and degradative enzymes of GAG and biological sulphation observed in diabetic rabbits. Administration of indigenous drug preparations (nisakathakathi Kashayam and rasnairandadi Kashayam and its mixture) ameliorated the diabetic hypertensive condition by reversing these effects and thereby arrested.
Kumari
K S
KS
Department of Biochemistry, University of Kerala, Trivandrum, India.
Devi
K S
KS
D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003921:Diabetes Mellitus, Experimental / Q000150:complications / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000378:metabolism*; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism*; D008297:Male; D008515:Medicine, Ayurvedic; D010946:Plants, Medicinal; D011817:Rabbits
D000959:Antihypertensive Agents; D006025:Glycosaminoglycans