[The body's nonspecific resistance factors in a localized experimental infection caused by Bacteroides].
Under local experimental infection induced by bacteroides of Fragilis group the factors of nonspecific organism resistance take an active part in the inflammation process. Phase changes of the state of monocytic-phagocytic and complement systems were observed. Peripheral blood leukocyte phagocytic activity decreased at the primary stage, then followed the complement activation by the alternative pathway mainly. The increase of phagocytic and metabolic activities of those phagocytes taking part in the inflammation, the complement at this stage is activated due to the classical pathway while being at the stage of clinic manifestation. Levels of antibody titres are also increasing.
Tyshko
A G
AG
Bebko
Iu M
IuM
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001442:Bacteroides Infections / Q000097:blood / Q000276:immunology*; D001441:Bacteroides fragilis / Q000276:immunology; D003170:Complement Pathway, Alternative; D003165:Complement System Proteins / Q000032:analysis; D004195:Disease Models, Animal; D006651:Histocytochemistry; D007113:Immunity, Innate; D007962:Leukocytes / Q000378:metabolism; D051379:Mice; D008810:Mice, Inbred C57BL; D010587:Phagocytosis; D013997:Time Factors
D000907:Antibodies, Bacterial; D003165:Complement System Proteins
Sostoianie faktorov nespetsificheskoĭ rezistentnosti organizma v usloviiakh lokalizovannoĭ éksperimental'noĭ infektsii, vyzvannoĭ bakteroidami.