title: Free hydroxyl radicals are formed on reaction between the neutrophil-derived species superoxide anion and hypochlorous acid.
abstract: Superoxide anion reacts with hypochlorous acid to yield free hydroxyl radicals, as shown by the hydroxylation of benzoate. This reaction is analogous to the Haber-Weiss reaction but in the absence of metal ions is at least six orders of magnitude faster.
authors.affiliation: Cancer Research Campaign Gray Laboratory, Northwood, Middlesex, UK.
authors.forename: L P
authors.initials: LP
authors.lastname: Candeias
authors.forename: K B
authors.initials: KB
authors.lastname: Patel
authors.forename: M R
authors.initials: MR
authors.lastname: Stratford
authors.forename: P
authors.initials: P
authors.lastname: Wardman
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005720:Gamma Rays; D017665:Hydroxyl Radical / Q000378:metabolism*; D006997:Hypochlorous Acid / Q000378:metabolism*; D008956:Models, Chemical; D009504:Neutrophils / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism*
chemical_list: D013481:Superoxides; D017665:Hydroxyl Radical; D006997:Hypochlorous Acid