title: Thrombolysis and stroke management.
abstract: Up to 90% of patients (those with occlusive stroke) may be candidates for clot lysis. Fears that lysis might cause hemorrhage appear to be unwarranted. The most important clinical lesson learned to date is that the earlier the intervention, the better the outcome. Issues such as the most efficient diagnosis, most amenable sites, and IV versus intra-arterial administration are under study.
authors.affiliation: Scripps Clinic and Research Institute, La Jolla, Calif.
authors.forename: G J
authors.initials: GJ
authors.lastname: del Zoppo
mesh_terms: D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D014057:Tomography, X-Ray Computed
chemical_list: D005343:Fibrinolytic Agents