Clostridium bifermentans serovar malaysia: characterization of putative mosquito larvicidal proteins.
The toxicity of Clostridium bifermentans serovar malaysia to mosquito larvae is due to protein toxins, belonging to a novel class of insecticidal toxins. Toxic extracts contains three major proteins of 66, 18 and 16 kDa. The 18-kDa and 16-kDa proteins are probably involved in toxicity. They are synthesised during sporulation, concomitant with activity. They are absent from non-toxic strains of C. bifermentans and are present at very low levels in non-toxic C. bifermentans serovar malaysia cultures produced at 42 degrees C. The 66-kDa protein is present throughout the growth phases of C. bifermentans serovar malaysia, and an immunologically related 66-kDa protein is present in non-toxic C. bifermentans strains.
Nicolas
L
L
Institut Pasteur, Unité des Bactéries Entomopathogènes, Paris, France.
Charles
J F
JF
de Barjac
H
H
D000818:Animals; D000852:Anopheles / Q000187:drug effects*; D001427:Bacterial Toxins / Q000096:biosynthesis / Q000737:chemistry / Q000633:toxicity*; D003013:Clostridium / Q000378:metabolism* / Q000502:physiology; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D013170:Spores; D013696:Temperature
D001427:Bacterial Toxins