[Polymorphism of the C-band segments of chromosomes 1, 9 and 16 in the peripheral blood lymphocytes of patients with endometrial cancer].
The paper presents results of investigation of constitutive heterochromatin of chromosomes 1, 9 and 16 in 23 patients with endometrial cancer and 5 women of the control group. The analysis was carried out on slides obtained by the routine method of the peripheral blood cell culture. The C-band segment variability was studied by the C-binding method. The investigation established an increase of polymorphism of constitutive heterochromatin in cancer patients, extreme variants and heteromorphism of homologues of chromosomes 1, 9 and 16. It is shown that polymorphism of the C-band on chromosomes 1, 9 and 16 in patients with cancer in their families increases as compared to the patients without cancer pathology in pedigrees.
Polishchuk
L Z
LZ
Nesina
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IP
D000328:Adult; D000368:Aged; D002478:Cells, Cultured / Q000648:ultrastructure; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002885:Chromosomes, Human, Pair 16; D002899:Chromosomes, Human, Pair 9; D016889:Endometrial Neoplasms / Q000097:blood / Q000235:genetics*; D005260:Female; D014644:Genetic Variation / Q000235:genetics; D006570:Heterochromatin / Q000648:ultrastructure; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008875:Middle Aged; D011110:Polymorphism, Genetic / Q000235:genetics*
D006570:Heterochromatin
Polimofizm C-segmentov 1, 9 i 16 khromosom v limfotsitakh perifericheskoĭ krovi bol'nykh rakom éndometriia.