BGP serum levels in patients with thyroid carcinoma before and 4-14 weeks after radioiodine therapy.
In the present short paper we compared the BGP and AP levels of 26 patients with thyroid carcinoma during radio-iodine therapy. BGP values reflect the bone turnover before and after radio-iodine therapy. There were no significant AP changes during this period. These results suggest that thyroid hormone has a direct effect on osteoblast function and that this effect can be best monitored by determination of BGP levels.
Stracke
H
H
Third Medical Department, University of Giessen, Federal Republic of Germany.
Federlin
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D002277:Carcinoma / Q000097:blood* / Q000201:enzymology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D015675:Osteocalcin / Q000097:blood*; D013964:Thyroid Neoplasms / Q000097:blood* / Q000201:enzymology / Q000532:radiotherapy*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
D007457:Iodine Radioisotopes; D015675:Osteocalcin; D013972:Thyrotropin; D000469:Alkaline Phosphatase; D013974:Thyroxine