title: Modelling photon transport in non-uniform media for SPECT with a vectorized Monte Carlo code.
abstract: A vectorized Monte Carlo code has been developed for modelling photon transport in non-uniform media for single-photon-emission computed tomography (SPECT). The code is designed to compute photon detection kernels, which are used to build system matrices for simulating SPECT projection data acquisition and for use in matrix-based image reconstruction. Non-uniform attenuating and scattering regions are constructed from simple three-dimensional geometric shapes, in which the density and mass attenuation coefficients are individually specified. On a Stellar GS1000 computer, Monte Carlo simulations are performed between 1.6 and 2.0 times faster when the vector processor is utilized than when computations are performed in scalar mode. Projection data acquired with a clinical SPECT gamma camera for a line source in a non-uniform thorax phantom are well modelled by Monte Carlo simulations. The vectorized Monte Carlo code was used to stimulate a 99Tcm SPECT myocardial perfusion study, and compensations for non-uniform attenuation and the detection of scattered photons improve activity estimation. The speed increase due to vectorization makes Monte Carlo simulation more attractive as a tool for modelling photon transport in non-uniform media for SPECT.
authors.affiliation: Department of Biomedical Engineering, Duke University, Durham, NC 27708.
authors.forename: M F
authors.initials: MF
authors.lastname: Smith
mesh_terms: D006801:Humans; D008954:Models, Biological; D009010:Monte Carlo Method; D055585:Physical Phenomena; D010825:Physics; D015899:Tomography, Emission-Computed, Single-Photon