Deletions and amplifications of tandemly arranged ribosomal 5S genes internal to a P element occur at a high rate in a dysgenic context.
We observed unusual kinds of rearrangements within tandemly clustered 5S genes internal to a P element in dysgenic context. Rearranged P transposons, initially containing eight 5S genes, were found to display discrete numbers of 5S genes, from 4 up to 17 units. Precise deletions and amplifications occurred at a high rate (40%), at both original and new insertion sites. These events can be explained by a "cut and paste" transposition model. Possible links between rearrangements due to dysgenic-like processes and concerted evolution are discussed.
Pâques
F
F
Laboratoire d'Embryologie Moléculaire et Expérimentale, Université Paris XI, Orsay, France.
Wegnez
M
M
D000818:Animals; D003433:Crosses, Genetic; D004251:DNA Transposable Elements; D004275:DNA, Ribosomal / Q000235:genetics / Q000302:isolation & purification; D004330:Drosophila / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics; D005260:Female; D005784:Gene Amplification; D017353:Gene Deletion; D015321:Gene Rearrangement; D008297:Male; D008957:Models, Genetic; D005810:Multigene Family; D011110:Polymorphism, Genetic; D012341:RNA, Ribosomal, 5S / Q000235:genetics*
D004251:DNA Transposable Elements; D004275:DNA, Ribosomal; D012341:RNA, Ribosomal, 5S