title: Preimplantation diagnosis.
abstract: Preimplantation embryonic biopsy and analysis offer couples at increased risk of having offspring affected with a genetic disorder the possibility of an early prenatal diagnosis. For many couples, this approach would avoid the issue of the selective termination of affected fetuses. Substantial advances have been made in the area of preimplantation diagnosis, but the possible difficulties with this approach cannot be ignored.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, UCSF School of Medicine 94143-0132.
authors.forename: J D
authors.initials: JD
authors.lastname: Goldberg
authors.forename: M C
authors.initials: MC
authors.lastname: Martin
authors.forename: R V
authors.initials: RV
authors.lastname: Lebo
authors.forename: R A
authors.initials: RA
authors.lastname: Pedersen
mesh_terms: D000818:Animals; D001757:Blastomeres / Q000166:cytology; D004624:Embryo Transfer; D047108:Embryonic Development; D005260:Female; D005307:Fertilization in Vitro; D030342:Genetic Diseases, Inborn / Q000175:diagnosis; D006801:Humans; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*