title: [Tick-borne encephalitis in Alsace].
abstract: Central European tick-borne encephalitis is mainly found in Central European countries and Austria where hundreds of cases are reported each year. Apart from 2 cases diagnosed in Alsace in 1968 and 1970 respectively, this disease was hitherto unknown in France. We report 8 new cases observed in Alsace between 1985 and 1990. Clinical presentation in these 10 patients was a pure meningitis syndrome in 4 cases and meningo-encephalitis in 6 cases, very severe in 3 of them. All patients recovered rapidly, and only 3 have slight sequelae. In a seroprevalence survey conducted in 1989 among 619 professional foresters of Eastern France, 8% were found to be seropositive, which suggests that the disease is often unrecognized. A study of the large series published in Austria and in other Central European countries has shown that the prognosis of tick-borne encephalitis is not always as favourable as it was in the Alsatian cases: severe sequelae or death occur in 1 to 2% of the patients. The need for a better detection of the disease and for vaccination of the subjects at risk must be emphasized.
authors.affiliation: Clinique Neurologique, CHU Strasbourg.
authors.forename: M
authors.initials: M
authors.lastname: Collard
authors.forename: J P
authors.initials: JP
authors.lastname: Gut
authors.forename: D
authors.initials: D
authors.lastname: Christmann
authors.forename: E
authors.initials: E
authors.lastname: Hirsch
authors.forename: G
authors.initials: G
authors.lastname: Nastorg
authors.forename: F
authors.initials: F
authors.lastname: Sellal
authors.forename: X
authors.initials: X
authors.lastname: Haller
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004675:Encephalitis, Tick-Borne / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D005260:Female; D016468:Forestry; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012698:Serologic Tests; D012699:Serology; D014611:Vaccination
vernacular_title: L'encéphalite à tiques en Alsace.