Familial occurrence of periapical cemental dysplasia.
A family with periapical cemental dysplasia is reported. The affected individuals displayed classical features of periapical cemental dysplasia on radiographic examination. The lesions consisted chiefly of radiolucent areas; however, some had central areas of radiodensity. Histopathological examination of one of the lesions revealed fibrous elements containing fused dense sclerotic cemental masses. Familial incidence of florid cemento-osseous dysplasia with an autosomal mode of inheritance has been reported previously. The condition described in this report appears to be different. However, the two conditions may be part of a spectrum occurring in a single genetic entity with the diversity possibly resulting from variable expressivity of a single gene.
Thakkar
N S
NS
Department of Medical Genetics St. Mary's Hospital, Manchester, UK.
Horner
K
K
Sloan
P
P
D002485:Cementoma / Q000000981:diagnostic imaging* / Q000235:genetics*; D003739:Dental Cementum / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D010483:Periapical Diseases / Q000000981:diagnostic imaging* / Q000235:genetics; D011859:Radiography