title: Opsoclonus-myoclonus syndrome: an autopsy study of three cases.
abstract: Opsoclonus-myoclonus is a rare clinical syndrome. We report three patients who died with a pure opsoclonus-myoclonus syndrome. The presentation, management and associations of this distinctive condition are discussed, and the results of detailed pathological examination described. In each case the only abnormality was perivascular collections of lymphocytes widely distributed in the brain. This supports an immune-mediated rather than structural aetiology.
authors.affiliation: Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom.
authors.forename: C A
authors.initials: CA
authors.lastname: Young
authors.forename: J M
authors.initials: JM
authors.lastname: MacKenzie
authors.forename: D W
authors.initials: DW
authors.lastname: Chadwick
authors.forename: I R
authors.initials: IR
authors.lastname: Williams
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009207:Myoclonus / Q000276:immunology / Q000473:pathology*; D015835:Ocular Motility Disorders / Q000276:immunology / Q000473:pathology*; D013577:Syndrome