Erythrocyte band 3-like protein immunoreactivity in the human brain cortex.
The immunoreactivity of erythrocyte band 3 (B3-IR)-related protein was estimated on cortex biopsies from the brains of 33 patients varying in age from 14-week-old fetus until 67 years of life. B3-IR was not a feature of embryonic brains. A positive reaction was restricted to neurons. It appeared at early postnatal life, increased sharply until 9 years, and than stayed approximately stable between 17 and 67 years of age. The results indicate that there is a positive relation between the amount of neuronal band 3-like protein and the stage of human brain development.
Renkawek
K
K
Research Laboratory of Morphological Neurology, University of Nijmegen, The Netherlands.
Bosman
G C
GC
van Workum
F P
FP
de Grip
W J
WJ
Gabreëls
F J
FJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D001457:Anion Exchange Protein 1, Erythrocyte / Q000737:chemistry* / Q000276:immunology / Q000378:metabolism; D002540:Cerebral Cortex / Q000737:chemistry* / Q000254:growth & development / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000737:chemistry* / Q000276:immunology; D005260:Female; D006801:Humans; D015151:Immunoblotting; D007150:Immunohistochemistry; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D011247:Pregnancy
D001457:Anion Exchange Protein 1, Erythrocyte