[Serum apolipoproteins in uremic patients].
Serum Apolipoproteins (Apo) and lipids were determined in 20 patients with uremia. The results were compared with those obtained in sex and age matched controls. The patients had significantly reduced level of Apo AI and ratio of Apo AI/Apo B100, and increased levels of Apo CII, Apo CIII. It was also found that the patients had normal levels of TC, TG and significant decrease of HDL-C, HDL2-C. These findings suggested that Chinese uremic patients had wide extensive Apo abnormalities which could induce disturbances of lipid metabolism and development of atherosclerosis although serum lipid levels were normal, and that Apo might be better predicators of cardiovascular complications than lipids in Chinese patients with uremia.
Fan
J M
JM
Dept. of Medicine, West China University of Medical Sciences, Chengdu.
Xu
G Z
GZ
D000328:Adult; D016632:Apolipoprotein A-I / Q000032:analysis; D053299:Apolipoprotein B-100; D053304:Apolipoprotein C-II; D053305:Apolipoprotein C-III; D001053:Apolipoproteins / Q000032:analysis*; D001055:Apolipoproteins B / Q000032:analysis; D001056:Apolipoproteins C / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D014511:Uremia / Q000097:blood*
D016632:Apolipoprotein A-I; D053299:Apolipoprotein B-100; D053304:Apolipoprotein C-II; D053305:Apolipoprotein C-III; D001053:Apolipoproteins; D001055:Apolipoproteins B; D001056:Apolipoproteins C