title: A multiscintigraphic approach to imaging of lymphedema and other causes of the congenitally enlarged extremity.
abstract: Nuclear imaging in the definition of the components of the congenitally enlarged extremity is important in the design of a successful therapeutic regimen. In our series of 32 patients evaluated for primary lymphedema, 85% were determined to have abnormalities that were not purely lymphatic in origin. The multiscintigraphic approach defines the components of the lymphatic and vascular systems with the use of technetium-99m [99mTc] antimony sulfide colloid (99mTc Sb2S3) for lymphatic, 99mTc diethylenetriamine pentacetic acid (DTPA) for capillary-interstitial, and 99mTc-tagged red blood cells for venous systems.
authors.affiliation: Department of Medical Imaging, Alfred I duPont Institute, Wilmington, DE 19899.
authors.forename: G A
authors.initials: GA
authors.lastname: Mandell
authors.forename: M A
authors.initials: MA
authors.lastname: Alexander
authors.forename: H T
authors.initials: HT
authors.lastname: Harcke
mesh_terms: D000965:Antimony; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000000981:diagnostic imaging; D008209:Lymphedema / Q000151:congenital / Q000000981:diagnostic imaging*; D008297:Male; D011877:Radionuclide Imaging; D017556:Technetium Compounds; D016284:Technetium Tc 99m Pentetate
chemical_list: D017556:Technetium Compounds; C019096:technetium Tc 99m antimony sulfide; D000965:Antimony; D016284:Technetium Tc 99m Pentetate