title: Identification and characterization of the iron compounds in bone marrow by means of Mössbauer spectrometry.
abstract: In order to determine and to demonstrate the cellular iron molecular states in hematopoietic bone marrow, direct investigations were performed by means of different and complementary spectroscopic techniques: optical absorption, electron spin resonance and Mössbauer spectrometry. In fact, the latter appears to have been the most informative. In addition to the hemoglobin forms, five- and six-coordination ligand protoporphyrins IX (monomeric and polymeric stacking, respectively) were observed. A small amount of non-hemic high-spin iron III storage component (ferritin) was measured. No diferric transferrin was detected. A ferrous compound was also observed and attributed to the mitochondrial iron pool.
authors.affiliation: Laboratoire de Biophysique, Faculté des Sciences Fondamentales et Appliquées de Poitiers, France.
authors.forename: C M
authors.initials: CM
authors.lastname: Jumpertz
authors.forename: J N
authors.initials: JN
authors.lastname: Rimbert
mesh_terms: D001853:Bone Marrow / Q000737:chemistry*; D005293:Ferritins / Q000032:analysis*; D006412:Hematopoietic Stem Cells / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000032:analysis* / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D011524:Protoporphyrins / Q000032:analysis*; D015204:Spectroscopy, Mossbauer / Q000379:methods; D014019:Tissue Donors; D014168:Transferrin / Q000032:analysis
chemical_list: D011524:Protoporphyrins; D014168:Transferrin; D005293:Ferritins; C028025:protoporphyrin IX; D007501:Iron