title: [Hypercalcemia caused by lithium medication in a female patient with a bipolar affective disorder].
abstract: In a 68-year-old woman, who used lithium carbonate because of longstanding recurring depression, an association was found between hypercalcaemia and the use of lithium. The serum calcium concentration appeared to be significantly correlated with the serum lithium concentration (y = 2.38 + 0.37x; r = 0.36; p = 0.009). There was a significant inverse correlation between the ratio of 24-hour urinary calcium and creatinine excretion and the serum lithium concentration (y = 0.80 - 0.22x; r = 0.43; p = 0.030). The association of hypercalcaemia and use of lithium has been reported before. The finding may be due to an effect of lithium on the parthyroids and (or) on the kidneys.
authors.affiliation: Afd. Interne Geneeskunde, Slingeland Ziekenhuis, Doetinchem.
authors.forename: A H
authors.initials: AH
authors.lastname: Mudde
authors.forename: R
authors.initials: R
authors.lastname: Kok
mesh_terms: D000368:Aged; D001714:Bipolar Disorder / Q000188:drug therapy*; D002118:Calcium / Q000097:blood / Q000652:urine; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced*; D016651:Lithium Carbonate / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D016651:Lithium Carbonate; D002118:Calcium
vernacular_title: Hypercalciëmie door lithiummedicatie bij een patiënte met een bipolaire affectieve stoornis.