title: The size of regional lymph nodes does not correlate with the presence or absence of metastasis in lymph nodes in rectal cancer.
abstract: We evaluated the relationship between the size of regional lymph nodes and the presence of metastasis in them in rectal cancer. Of 1,064 lymph nodes in 46 specimens, 133 (13%) were found to have metastases. A half of the positive nodes and most of the negative ones were less than 5 mm in diameter. Therefore, we must find lymph nodes smaller than 5 mm in diameter for assessment of lymph node metastasis. Although positive nodes were larger than negative ones, there was no significant difference. However, when comparing the size of lymph nodes in relation to their location, the epi- and pararectal lymph nodes larger than 10 mm in diameter were highly suggestive of metastases, but the size of the lymph node was not a reliable indicator of lymph node metastases in other situations.
authors.affiliation: Department of Surgery, Akita University, School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kotanagi
authors.forename: T
authors.initials: T
authors.lastname: Fukuoka
authors.forename: Y
authors.initials: Y
authors.lastname: Shibata
authors.forename: T
authors.initials: T
authors.lastname: Yoshioka
authors.forename: O
authors.initials: O
authors.lastname: Aizawa
authors.forename: Y
authors.initials: Y
authors.lastname: Saito
authors.forename: G E
authors.initials: GE
authors.lastname: Tur
authors.forename: K
authors.initials: K
authors.lastname: Koyama
mesh_terms: D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology*; D012004:Rectal Neoplasms / Q000473:pathology*