Immunological infertility in humans.
This review deals with some of the most controversial problems in the field of immunologic infertility and antisperm antibodies (ASA) in humans: (a) sperm antigens and their identification; (b) the aetiopathogenesis of the immune reaction and the biological effects of ASA; (c) laboratory tests set up for ASA detection, and (d) the therapy for immunologic infertility both in vivo and in vitro.
Dondero
F
F
University Laboratory of Seminology and Immunology of Reproduction, University of Rome La Sapienza, Italy.
Lenzi
A
A
Gandini
L
L
Lombardo
F
F
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001323:Autoantibodies / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D005260:Female; D005306:Fertilization; D005832:Genital Diseases, Male / Q000150:complications / Q000276:immunology; D005837:Genitalia, Male / Q000276:immunology; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D008297:Male; D011247:Pregnancy; D013094:Spermatozoa / Q000276:immunology*
D000305:Adrenal Cortex Hormones; D001323:Autoantibodies; D001324:Autoantigens