title: Permeability of dentin to adhesive agents.
abstract: The permeability of dentin to adhesive agents is of crucial importance in obtaining good dentinal bonding. In those systems that remove the smear layer, the opportunity exists for resin to infiltrate both tubules and intertubular dentin. Resin penetration into tubules can effectively seal the tubules and can contribute to bond strength if the resin bonds to the tubule wall. Resin infiltration into intertubular dentin can only occur if the mineral phase of dentin is removed by acidic conditioners or chelators. This is more easily accomplished in fractured dentin than in smear layer-covered dentin because of the residual collagen debris that remains on the surface following acid etching of smear layers. The channels for resin infiltration are the perifibrillar spaces created around the collagen fibers of dentin following removal of apatite mineral by acids. The diffusion of adhesive resins through these narrow, tortuous, long channels in 1 to 2 minutes offers a number of challenges that require further research.
authors.affiliation: Department of Oral Biology, Medical College of Georgia, School of Dentistry, Augusta 30912.
authors.forename: D H
authors.initials: DH
authors.lastname: Pashley
authors.forename: B
authors.initials: B
authors.lastname: Ciucchi
authors.forename: H
authors.initials: H
authors.lastname: Sano
authors.forename: J A
authors.initials: JA
authors.lastname: Horner
mesh_terms: D000134:Acid Etching, Dental; D003094:Collagen; D001840:Dental Bonding; D003804:Dentin / Q000648:ultrastructure*; D003806:Dentin Permeability; D017220:Dentin-Bonding Agents; D006801:Humans; D008855:Microscopy, Electron, Scanning; D012117:Resins, Synthetic; D016369:Smear Layer; D013499:Surface Properties; D017001:Tooth Demineralization / Q000503:physiopathology
chemical_list: D017220:Dentin-Bonding Agents; D012117:Resins, Synthetic; D003094:Collagen