title: Is there a best castration?
abstract: Androgen ablation by bilateral orchidectomy has long been considered the gold standard against which other forms of treatment for the management of advanced prostate cancer can be evaluated. It now is recognized that the use of luteinizing hormone-releasing hormone analogs provides a form of primary endocrine therapy that is as effective as surgical castration for the treatment of disseminated disease.
authors.affiliation: Tenovus Cancer Research Centre, University of Wales College of Medicine, Heath Park, Cardiff, England.
authors.forename: K
authors.initials: K
authors.lastname: Griffiths
mesh_terms: D000726:Androgen Antagonists / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004054:Diethylstilbestrol / Q000627:therapeutic use; D017273:Goserelin / Q000627:therapeutic use; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009919:Orchiectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000601:surgery*; D013739:Testosterone / Q000097:blood
chemical_list: D000726:Androgen Antagonists; D017273:Goserelin; D013739:Testosterone; D004054:Diethylstilbestrol; D007986:Luteinizing Hormone