Thrombolysis as an adjunct to angioplasty.
Acute coronary occlusion following angioplasty is a significant cause of in-hospital morbidity and mortality. Following acute closure, several strategies can be used to reopen the artery, including redilation, adjunctive thrombolysis, or other interventional techniques. Definite indications for thrombolysis as an adjunct to angioplasty include (1) recently occluded saphenous vein grafts, patent native vessels, or saphenous grafts with abundant intracoronary thrombus; and (2) acute closure during angioplasty, which is presumably secondary to thrombus formation and resistant to redilation alone.
Ambrose
J A
JA
Department of Medicine, Mount Sinai Hospital, New York, New York 10029.
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D002986:Clinical Trials as Topic; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology / Q000517:prevention & control*; D015912:Thrombolytic Therapy