Generation of reentry in anisotropic myocardium.
BACKGROUND
We investigated numerically the effects of the rotation of fiber axis orientation through the myocardial wall on wave propagation.


RESULTS
We show that because of this rotation and inherent discrete properties of myocardium, a premature stimulus can create unidirectional conduction block leading to reentry.


CONCLUSIONS
The dynamics of the subsequent reentrant patterns are complicated by the presence of rotational anisotropy, as the center of reentry drifts, and the reentry terminates in finite time when it collides with the domain boundary.
Panfilov
A V
AV
Department of Mathematics, University of Utah, Salt Lake City.
Keener
J P
JP
D016880:Anisotropy; D003198:Computer Simulation; D006321:Heart / Q000502:physiology*; D006801:Humans; D012399:Rotation