title: Determination of the percentage purity, active ingredients and other parameters in paracetamol and chloroquine syrups.
abstract: In this paper the percentage purity, active ingredients, specific gravity and the pH of paracetamol and chloroquine syrups were determined. For paracetamol the percentage purity ranged from 102.6-106.67, while the active ingredients (in mg/5 ml base) ranged from 123.2-128. The specific gravity ranged from 1.13-1.24 and the pH from 4.16-5.32. For the chloroquine the percentage purity ranged from 97-106.3, and the active ingredient 48.5-53.13, the specific gravity 1.17-1.27 and the pH 2.44-4.17. The results are discussed in relation to the purity, active ingredients and sources of the drugs. The drugs were coded. The paracetamol had a code of 1p-5p while the chloroquine was coded from 1c-5c.
authors.affiliation: Department of Biochemistry, College of Medical Sciences, University of Calabar, Nigeria.
authors.forename: E O
authors.initials: EO
authors.lastname: Udosen
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage / Q000737:chemistry / Q000592:standards* / Q000600:supply & distribution; D000284:Administration, Oral; D002738:Chloroquine / Q000008:administration & dosage / Q000737:chemistry / Q000592:standards* / Q000600:supply & distribution; D004340:Drug Contamination; D006863:Hydrogen-Ion Concentration; D009549:Nigeria; D004366:Nonprescription Drugs / Q000008:administration & dosage / Q000737:chemistry / Q000592:standards* / Q000600:supply & distribution; D011786:Quality Control; D013046:Specific Gravity; D013810:Therapeutic Equivalency
chemical_list: D004366:Nonprescription Drugs; D000082:Acetaminophen; D002738:Chloroquine