Effect of guar gum on hunger and satiety after meals of differing fat content: relationship with gastric emptying.
To determine whether the satiating effects of fiber are due to delaying gastric emptying or slowing absorption of meals, 3% guar gum was added to high- and low-fat soups and gastric emptying rate, hunger, and satiety were measured in eight male volunteers. Guar gum delayed the emptying of the low-fat soup but the small delays in the return of hunger and decline of fullness were significantly correlated with the gastric emptying, suggesting mediation by gastric mechanoreceptors. The high-fat soup also emptied more slowly but this had no effect on the return of hunger or the decline in fullness. The delays in the return of hunger and decline of fullness were far greater when guar gum was added to the fatty soup; these delays were not correlated with the small additional delay in gastric emptying. This is more compatible with slowed absorption and prolonged contact of nutrients with intestinal chemoreceptors.
French
S J
SJ
Centre for Human Nutrition, University of Sheffield, Northern General Hospital, UK.
Read
N W
NW
D000328:Adult; D000704:Analysis of Variance; D004041:Dietary Fats / Q000008:administration & dosage*; D004043:Dietary Fiber; D005685:Galactans / Q000494:pharmacology*; D005746:Gastric Emptying / Q000502:physiology*; D006801:Humans; D006815:Hunger / Q000502:physiology*; D016014:Linear Models; D008297:Male; D008351:Mannans / Q000494:pharmacology*; D053149:Plant Gums; D012528:Satiety Response / Q000502:physiology*; D013997:Time Factors
D004041:Dietary Fats; D004043:Dietary Fiber; D005685:Galactans; D008351:Mannans; D053149:Plant Gums; C007894:guar gum