title: The effects of hyperbaric oxygenation on bone-titanium implant interface strength with and without preceding irradiation.
abstract: This study investigated the influence of a single 15-Gy dose of irradiation on the capacity of titanium screws to integrate in irradiated bone tissue. The biomechanical force necessary to unscrew the titanium implants 8 weeks after placement was 54% lower for implants in irradiated bone tissue compared to implants in nonirradiated bone tissue. Postirradiation use of hyperbaric oxygen treatment at 2.8 ATA (2-hour daily treatments for 21 days) increased the biomechanical force necessary to unscrew the titanium implants by 44% in irradiated bone and by 22% in nonirradiated bone.
authors.affiliation: Biomaterials Group, Department of Handicap Research, University of Gothenburg, Sweden.
authors.forename: K
authors.initials: K
authors.lastname: Johnsson
authors.forename: A
authors.initials: A
authors.lastname: Hansson
authors.forename: G
authors.initials: G
authors.lastname: Granström
authors.forename: M
authors.initials: M
authors.lastname: Jacobsson
authors.forename: I
authors.initials: I
authors.lastname: Turesson
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001861:Bone Regeneration / Q000528:radiation effects*; D016723:Bone Remodeling / Q000528:radiation effects; D001842:Bone and Bones / Q000378:metabolism / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006931:Hyperbaric Oxygenation; D008297:Male; D016348:Osseointegration / Q000528:radiation effects*; D010710:Phosphates / Q000378:metabolism; D019736:Prostheses and Implants; D011817:Rabbits; D011837:Radiation-Protective Agents; D014025:Titanium
chemical_list: D010710:Phosphates; D011837:Radiation-Protective Agents; D014025:Titanium