Norpethidine toxicity and patient controlled analgesia.
Patient-controlled analgesia (PCA) with i.v. opioids is prescribed increasingly. We report three cases of norpethidine toxicity in patients receiving pethidine by PCA.
Stone
P A
PA
Department of Anaesthesia and Intensive Care, Royal Adelaide Hospital, South Australia.
Macintyre
P E
PE
Jarvis
D A
DA
D000328:Adult; D016058:Analgesia, Patient-Controlled; D002800:Cholinesterase Inhibitors / Q000009:adverse effects* / Q000097:blood; D005260:Female; D006801:Humans; D008614:Meperidine / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy
D002800:Cholinesterase Inhibitors; D008614:Meperidine; C002752:normeperidine