Mucosal adenosine deaminase activity and gastric ulcer healing.
Adenosine deaminase activity was studied in gastric corpus mucosa close to an ulcer crater. It was found that 6 weeks of therapy with ranitidine was accompanied by a decrease in enzyme activity in the mucosa around healed ulcers and an increase around those which failed to heal. The different activities of adenosine deaminase in the vicinity of healed and unhealed ulcers may indicate its possible role in peptic ulcer healing.
Namiot
Z
Z
Department of Physiology, Medical School, Bialystok, Poland.
Marcinkiewicz
M
M
Jaroszewicz
W
W
Stasiewicz
J
J
Gorski
J
J
D000243:Adenosine Deaminase / Q000502:physiology*; D000328:Adult; D005260:Female; D005753:Gastric Mucosa / Q000201:enzymology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011899:Ranitidine / Q000627:therapeutic use; D013276:Stomach Ulcer / Q000188:drug therapy / Q000201:enzymology* / Q000209:etiology
D011899:Ranitidine; D000243:Adenosine Deaminase