[Effect of suo quan pill for reducing clozapine induced salivation].
40 Schizophrenic inpatients with clozapine induced salivation were divided into two groups randomly. They were treated with Suo Quan pill and a control study of the placebo (neutral pill) for reducing clozapine induced salivation. These cases were also classified by TCM Syndrome Differentiation and laboratory examinations were performed.


RESULTS
There was a significant difference in effect on salivation between the therapeutic group (21 cases) and the controlled group (19 cases), P < 0.01. According to their TCM subtypes two subtypes (Stagnation of Phlegm-Dampness and Yin Deficiency) showed the best results. No correlation between the peripheral clozapine level and salivation was found. No side effect was recorded.
Kang
B
B
Nanjing Neuropsychiatric Hospital.
D000328:Adult; D003024:Clozapine / Q000009:adverse effects*; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy; D012798:Sialorrhea / Q000139:chemically induced / Q000188:drug therapy*
D004365:Drugs, Chinese Herbal; D003024:Clozapine