title: Ocular involvement correlated with age in patients affected by major and intermedia beta-thalassemia treated or not with desferrioxamine.
abstract: We examined 25 patients affected from Cooley's disease and five by beta-thalassemia intermedia. The mean age was 15 +/- 6.3 years. Fifteen patients, (18 years or older) three of them affected by beta-thalassemia intermedia, presented ocular abnormalities. So it was impossible to establish a correlation between laboratory data and ocular damages; their observation, with reference to untreated beta-thalassemia subjects, suggested that ocular abnormalities cannot be only attributed to desferrioxamine treatment.
authors.affiliation: Eye Clinic First School of Medicine, University of Naples, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Rinaldi
authors.forename: M
authors.initials: M
authors.lastname: Della Corte
authors.forename: V
authors.initials: V
authors.lastname: Ruocco
authors.forename: C
authors.initials: C
authors.lastname: D'Onofrio
authors.forename: G
authors.initials: G
authors.lastname: Zanotta
authors.forename: A
authors.initials: A
authors.lastname: Romano
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000793:Angioid Streaks / Q000209:etiology; D002386:Cataract / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003676:Deferoxamine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D012164:Retinal Diseases / Q000209:etiology; D017086:beta-Thalassemia / Q000150:complications / Q000188:drug therapy*
chemical_list: D003676:Deferoxamine