title: Expression of the pS2 gene in breast cancer--a comparison of pS2 protein radioimmunoassay and immunohistochemistry.
abstract: pS2 expression was studied in a series of 82 primary breast carcinomas using and comparing a radioimmunoassay (RIA) technique and immunohistochemistry (IPOX). There was close correlation of the results obtained with each technique. Accurate and reliable determination of pS2 status in breast cancer can be made on the basis of immunohistochemistry using formalin fixed paraffin embedded sections. Immunohistochemical determination of pS2 status may be used in situations where the RIA technique cannot be applied, i.e. instances when fresh tumor tissue is not available.
authors.affiliation: Hospital Pathology Service, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
authors.forename: P D
authors.initials: PD
authors.lastname: Robbins
authors.forename: E
authors.initials: E
authors.lastname: Hähnel
authors.forename: G F
authors.initials: GF
authors.lastname: Sterrett
authors.forename: J
authors.initials: J
authors.lastname: Harvey
authors.forename: S
authors.initials: S
authors.lastname: Carrello
authors.forename: R
authors.initials: R
authors.lastname: Hähnel
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics*; D002277:Carcinoma / Q000235:genetics*; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007150:Immunohistochemistry; D009363:Neoplasm Proteins / Q000032:analysis*; D011506:Proteins; D011863:Radioimmunoassay; D015203:Reproducibility of Results; D000071163:Trefoil Factor-1; D025521:Tumor Suppressor Proteins
chemical_list: D009363:Neoplasm Proteins; D011506:Proteins; C051838:TFF1 protein, human; D000071163:Trefoil Factor-1; D025521:Tumor Suppressor Proteins