Cutaneous granuloma with ataxia telangiectasia--a case report and review of literature.
A patient is reported who had ataxia telangiectasia with multiple cutaneous lesions mainly on the limbs, which showed atrophy and scarring. Histopathology of these skin lesions showed tuberculoid granulomas without frank collagen necrobiosis in the dermis. Chromosomal analysis revealed a translocation between 7 and 14 as well as deletion of chromosomes 4 and 6.
Joshi
R K
RK
Division of Dermatology, Riyadh Armed Forces Hospital, Saudi Arabia.
al Asiri
R H
RH
Haleem
A
A
Abanmi
A
A
Patel
C K
CK
D001260:Ataxia Telangiectasia / Q000235:genetics*; D001859:Bone Neoplasms / Q000235:genetics*; D002648:Child; D002872:Chromosome Deletion; D005260:Female; D006099:Granuloma / Q000235:genetics*; D006801:Humans; D008223:Lymphoma / Q000235:genetics*; D012878:Skin Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic