[Acquired localized epidermolysis bullosa. A case with scalp involvement and immunoelectron microscopic study].
The case of a 59-year old man who had a clinical Brunsting-Perry pemphigoid localized to the scalp is described. Direct immunoelectron microscopy demonstrated IgG and C3 immune deposits in the anchoring fibril zone, as in epidermolysis bullosa acquisita. No circulating antibodies were detected by Western immunoblotting on epidermal and dermal extracts. These findings show that Brunsting-Perry pemphigoid is not an immunological entity and that it widens the clinical spectrum of epidermolysis bullosa acquisita.
Karpouzis
A
A
Clinique Dermatologique, Hôpital Saint-Louis, Paris.
Prost
C
C
Cordoliani
F
F
Viguier
D
D
Blum
L
L
Puissant
A
A
D001323:Autoantibodies / Q000032:analysis; D003937:Diagnosis, Differential; D016107:Epidermolysis Bullosa Acquisita / Q000150:complications / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008297:Male; D016253:Microscopy, Immunoelectron; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000473:pathology; D012536:Scalp Dermatoses / Q000209:etiology / Q000276:immunology / Q000473:pathology*
D001323:Autoantibodies
Epidermolyse bulleuse acquise localisée. Un cas avec atteinte du cuir chevelu étudié en immunomicroscopie électronique.