Hormone replacement therapy for prevention and treatment of osteoporosis.
Estrogen therapy is clearly effective in the prevention and treatment of osteoporosis. Several estrogens and routes of administration are available. A progestin is required to protect the endometrium if the patient has a uterus. The duration of treatment required is unknown but probably is > or = 10 years for prevention and may be life-long, which is the requirement for patients with established disease. A regimen of patient monitoring can be easily established and must become routine for all patients on long-term treatment.
Lindsay
R
R
Regional Bone Center, Helen Hayes Hospital, West Haverstraw, New York 10993.
D000279:Administration, Cutaneous; D000284:Administration, Oral; D016903:Drug Monitoring; D015914:Estrogen Replacement Therapy / Q000379:methods; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007044:Hysterectomy; D015663:Osteoporosis, Postmenopausal / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control*