title: Trisomy 4 in a case of acute myelogenous leukemia accompanied by subcutaneous soft tissue tumors. Report of a case and review of the literature.
abstract: We report a patient with acute myelogenous leukemia [AML, French-American-British classification (FAB) M2] with trisomy 4, who developed subcutaneous soft tissue tumors at the time leukemia was diagnosed. A review of the literature on AML with trisomy 4 suggests a relation between trisomy 4 and tumor formation of leukemic cells.
authors.affiliation: Department of Internal Medicine, Kumamoto National Hospital, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Suenaga
authors.forename: I
authors.initials: I
authors.lastname: Sanada
authors.forename: A
authors.initials: A
authors.lastname: Tsukamoto
authors.forename: M
authors.initials: M
authors.lastname: Sato
authors.forename: F
authors.initials: F
authors.lastname: Kawano
authors.forename: T
authors.initials: T
authors.lastname: Shido
authors.forename: K
authors.initials: K
authors.lastname: Miura
authors.forename: R
authors.initials: R
authors.lastname: Tominaga
mesh_terms: D000368:Aged; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D017254:Leukemic Infiltration / Q000235:genetics*; D012983:Soft Tissue Neoplasms / Q000235:genetics*; D014314:Trisomy