title: Novel genes in the human major histocompatibility complex class-II region.
abstract: Recent studies have identified a number of new genes mapping to the class-II region of the human major histocompatibility complex. Functionally these can be grouped into three broad categories: those encoding the new class-II-related genes DMA and DMB; those involved in aspects of class-I antigen-processing and presentation, and those with no apparent association with the immune system. There is evidence that further factors involved in class-II antigen presentation are located in the DMB to DQB1 interval.
authors.affiliation: Human Immunogenetics Laboratory, Imperial Cancer Research Fund, London, UK.
authors.forename: A
authors.initials: A
authors.lastname: Kelly
authors.forename: J
authors.initials: J
authors.lastname: Trowsdale
mesh_terms: D017951:Antigen Presentation; D006682:HLA-DP Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006801:Humans; D008285:Major Histocompatibility Complex / Q000276:immunology*
chemical_list: D006682:HLA-DP Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II