Progressive systemic sclerosis preceded by malignant lymphoma.
We report a patient who suffered from progressive systemic sclerosis (PSS) two years after she showed evidence of malignant lymphoma of the jejunum. Surgical resection of the tumor mass and VEMP regimen were successful; the patient was in remission but died of acute respiratory failure five years later. Although several reports have reported malignant lymphoma associated with PSS, lymphoma antecedent to PSS is rarely seen. Immune abnormalities including a high titer of antinuclear factor and positive anti-RNP antibodies were suspected to be associated with the development of PSS in our case.
Yamamoto
T
T
Department of Dermatology, Kiryu Kosei General Hospital, Gunma, Japan.
Furuse
Y
Y
Nishioka
K
K
D005260:Female; D006801:Humans; D007580:Jejunal Neoplasms / Q000150:complications / Q000473:pathology; D008223:Lymphoma / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology