title: Identification of an allelic variant of isoform MLC1-V/sB (human myosin light chain).
abstract: A study of 250 specimens of human myocardium by two-dimensional gel electrophoresis revealed an allelic variant of isoform MLC1-V/sB, which was identified by immunoblotting with monoclonal antibody against MLC1-V/sB and peptide mapping after in situ tryptic digestion of electroblotted proteins. The substitution Asn-144 for His-144 was found in this new allelic variant of MLC1-V/sB.
authors.affiliation: Research Centre of Medical Genetics, Russian Academy of Medical Sciences, Moscow.
authors.forename: A V
authors.initials: AV
authors.lastname: Laptev
authors.forename: S S
authors.initials: SS
authors.lastname: Shishkin
authors.forename: L I
authors.initials: LI
authors.lastname: Kovalyov
authors.forename: M A
authors.initials: MA
authors.lastname: Galyuk
authors.forename: A Kh
authors.initials: AKh
authors.lastname: Musolyamov
authors.forename: T A
authors.initials: TA
authors.lastname: Egorov
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D015180:Electrophoresis, Gel, Two-Dimensional; D014644:Genetic Variation; D006801:Humans; D008969:Molecular Sequence Data; D009206:Myocardium / Q000737:chemistry; D009218:Myosins / Q000737:chemistry / Q000235:genetics*
chemical_list: D009218:Myosins