title: Studies on the acetogenins of Formosan annonaceous plants. II. Cytotoxic acetogenins from Annona reticulata.
abstract: Using cytotoxicity as a guide to fractionation, one novel acetogenin, annoreticuin-9-one [3], and four known cytotoxic acetogenins, squamone [4], solamin [5], annomonicin [6] and rolliniastatin 2 [7], were isolated from active extracts of the leaves of the Formosan plant Annona reticulata. Their structures were elucidated on the basis of uv, ir, 1H- and 13C-nmr, and ms data of the natural compounds and their derivatives.
authors.affiliation: Department of Microbiology, Kaohsiung Medical College, Taiwan, Republic of China.
authors.forename: F R
authors.initials: FR
authors.lastname: Chang
authors.forename: Y C
authors.initials: YC
authors.lastname: Wu
authors.forename: C Y
authors.initials: CY
authors.lastname: Duh
authors.forename: S K
authors.initials: SK
authors.lastname: Wang
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005663:Furans / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D013624:Taiwan
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D005663:Furans; D010936:Plant Extracts