title: A dimensional and categorical approach to the symptomatology of recent-onset schizophrenia.
abstract: Sixty-five patients with recent-onset schizophrenia were assessed with two widely used symptom scales, the Brief Psychiatric Rating Scale-Expanded (BPRS-E) and the Psychiatric Assessment Scale (Manchester scale). Principal components analysis of the BPRS-E scores yielded a four-dimensional structure: positive symptoms, negative symptoms, disorganization, and depression. With the Psychiatric Assessment Scale, three dimensions were found: the positive symptoms (delusions, hallucinations) and disorganization (incoherence) appeared in one dimension. A categorical analysis resulted in predominantly positive, negative, and disorganized clusters, but more than half of the sample could not be allocated to any of these groups.
authors.affiliation: Department of Psychiatry, Leiden University, The Netherlands.
authors.forename: A J
authors.initials: AJ
authors.lastname: Van der Does
authors.forename: D H
authors.initials: DH
authors.lastname: Linszen
authors.forename: P M
authors.initials: PM
authors.lastname: Dingemans
authors.forename: M A
authors.initials: MA
authors.lastname: Nugter
authors.forename: W F
authors.initials: WF
authors.lastname: Scholte
mesh_terms: D000293:Adolescent; D000328:Adult; D016000:Cluster Analysis; D003702:Delusions / Q000145:classification / Q000175:diagnosis; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis; D016002:Discriminant Analysis; D005163:Factor Analysis, Statistical; D005260:Female; D006212:Hallucinations / Q000145:classification / Q000175:diagnosis; D006760:Hospitalization; D006801:Humans; D008297:Male; D008960:Models, Psychological; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D012559:Schizophrenia / Q000145:classification / Q000175:diagnosis*; D012565:Schizophrenic Psychology