title: Effect of vitamin-E on high fat diet induced hyperlipidemia in rats.
abstract: High fat diet intake in rats resulted in hyperlipidemia which was evidenced by elevated levels of plasma cholesterol, free fatty acids, triglycerides and increased LDLc/HDLc ratio. Vitamin E (400 mg/kg body wt/day) administration for 60 days prevented the elevations in plasma lipid levels. It reduced LDLc/HDLc ratio, lipid peroxide levels and elevated the level of reduced glutathione (GSH) in hyperlipidemic rats. Vitamin-E was non-toxic.
authors.affiliation: Department of Biochemistry, Bharathi Women's College, North Madras, India.
authors.forename: R
authors.initials: R
authors.lastname: Manimegalai
authors.forename: A
authors.initials: A
authors.lastname: Geetha
authors.forename: K
authors.initials: K
authors.lastname: Rajalakshmi
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000097:blood; D004041:Dietary Fats / Q000009:adverse effects*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006949:Hyperlipidemias / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000097:blood; D014810:Vitamin E / Q000627:therapeutic use*
chemical_list: D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D014280:Triglycerides; D014810:Vitamin E; D002784:Cholesterol