[The effect of captopril on the arterial pressure, structural resistance and vascular reactivity of the kidney in rats with nephrogenic hypertension].
The angiotensin-converting enzyme inhibiting agent captopryl suppressed a moderate hypertension in rats with pyelonephritis and with ureteral obstruction, but not in rats with ureteral obstruction combined with the renal artery constriction. The suppression of the hypertension was accompanied by a reversion of structural alterations in the blood vessels.
Rodionov
I M
IM
Tarasova
O S
OS
Storozhevykh
T P
TP
Kuzenkov
V S
VS
Pinelis
V G
VG
Sokolova
R I
RI
Rudneva
L F
LF
Markov
Kh M
KhM
Koshelev
V B
VB
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002216:Captopril / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004927:Escherichia coli Infections / Q000150:complications / Q000503:physiopathology; D006869:Hydronephrosis / Q000150:complications / Q000503:physiopathology; D006978:Hypertension, Renovascular / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D010656:Phenylephrine / Q000494:pharmacology; D011704:Pyelonephritis / Q000150:complications / Q000503:physiopathology; D051381:Rats; D012077:Renal Artery / Q000187:drug effects* / Q000503:physiopathology; D014655:Vascular Resistance / Q000187:drug effects*
D010656:Phenylephrine; D002216:Captopril
Vliianie kaptoprila na arterial'noe davlenie, strukturnoe soprotivlenie i reaktivnost' sosudov pochi u krys s nefrogennoĭ gipertenzieĭ.