title: Primary suprasellar germ cell tumor in a dog.
abstract: A 5-year-old female Rottweiler was examined because of a history of progressive CNS depression and apparent blindness. Findings included retinal degeneration and cranial nerve deficits as well as pronounced hypercholesterolemia and bradycardia. At necropsy, a 3-cm soft, tan mass was found on the ventral surface of the rostral portion of the brain, encompassing the hypophysis and filling the sella tursica. Histologic examination of tumor sections identified 3 distinct cell types. The location and histologic features of the solitary tumor were most consistent with classification as a primary intracranial germ cell tumor.
authors.affiliation: Department of Veterinary Pathobiology, Texas A&M University, College Station 77843-4467.
authors.forename: W R
authors.initials: WR
authors.lastname: Hare
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D018237:Germinoma / Q000473:pathology / Q000662:veterinary*; D012658:Sella Turcica