title: Probing structure-function relationships of tissue-type plasminogen activator by oligonucleotide-mediated site-specific mutagenesis.
authors.affiliation: Department of Vascular Biology, Scripps Research Institute, La Jolla, California 92037.
authors.forename: E L
authors.initials: EL
authors.lastname: Madison
authors.forename: J E
authors.initials: JE
authors.lastname: Sambrook
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017104:Bacteriophage M13; D002460:Cell Line; D003001:Cloning, Molecular / Q000379:methods; D004926:Escherichia coli; D015870:Gene Expression; D006801:Humans; D007202:Indicators and Reagents; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D017395:Plasminogen Activator Inhibitor 1 / Q000494:pharmacology; D017354:Point Mutation; D011487:Protein Conformation; D017510:Protein Folding; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D010959:Tissue Plasminogen Activator / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism*; D014162:Transfection / Q000379:methods
chemical_list: D007202:Indicators and Reagents; D017395:Plasminogen Activator Inhibitor 1; D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator