Ranitidine-induced bradycardia in a neonate--a first report.
Bradycardia, an extremely rare side-effect of ranitidine therapy is described in a 4-day-old full-term male neonate, who was admitted because of massive gastro-intestinal bleeding. Two hours after the intravenous injection of 1 mg/kg body weight per day, ECG showed sinus bradycardia of 60 beats/min with normal axis and QRS complex. The bradycardia gradually resolved in the next 24 h.
Nahum
E
E
Department of Neonatology, Beilinson Medical Centre, Tel Aviv University, Petah Tiqva, Israel.
Reish
O
O
Naor
N
N
Merlob
P
P
D001919:Bradycardia / Q000139:chemically induced*; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011899:Ranitidine / Q000009:adverse effects* / Q000627:therapeutic use
D011899:Ranitidine