title: Methoxylation of cocaine reduces binding affinity and produces compounds of differential binding and dopamine uptake inhibitory activity: discovery of a weak cocaine "antagonist".
authors.affiliation: Mayo Foundation for Medical Education and Research, Jacksonville, Florida 32224.
authors.forename: D
authors.initials: D
authors.lastname: Simoni
authors.forename: J
authors.initials: J
authors.lastname: Stoelwinder
authors.forename: A P
authors.initials: AP
authors.lastname: Kozikowski
authors.forename: K M
authors.initials: KM
authors.lastname: Johnson
authors.forename: J S
authors.initials: JS
authors.lastname: Bergmann
authors.forename: R G
authors.initials: RG
authors.lastname: Ball
mesh_terms: D003042:Cocaine / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors* / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D004298:Dopamine / Q000378:metabolism*; D008454:Mazindol / Q000378:metabolism; D015394:Molecular Structure; D013329:Structure-Activity Relationship
chemical_list: C084740:methyl 3-benzoyloxy-7-methoxy-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylate; D008454:Mazindol; D003042:Cocaine; D004298:Dopamine