title: Preparation and in vivo evaluation of a newly developed bioglass ceramic.
abstract: This paper presents details of the fabrication of a glass ceramic, and its application as an artificial bone prosthetic material. This new bioglass ceramic, with composition of Na2O 8.4%, CaO 40.6%, P2O5 12% and SiO2 39%, had 160-190 MPa and 800-980 MPa of three-point bending strength and compressive strength respectively. The ceramic has a (Na, Ca) (P, Si) O3 crystalline phase with a uniform crystal size of about 10 microns, which was attributed to the high nucleation frequency. The rabbit condyle test showed that the material formed a tight chemical bond with biological texture and had good biocompatibility.
authors.affiliation: Center for Biomedical Engineering, College of Medicine, National Taiwan University, Taipei, ROC.
authors.forename: F H
authors.initials: FH
authors.lastname: Lin
authors.forename: H C
authors.initials: HC
authors.lastname: Liu
authors.forename: M H
authors.initials: MH
authors.lastname: Hon
authors.forename: C Y
authors.initials: CY
authors.lastname: Wang
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D002516:Ceramics; D005069:Evaluation Studies as Topic; D005269:Femur / Q000000981:diagnostic imaging / Q000601:surgery; D008422:Materials Testing; D016348:Osseointegration; D019736:Prostheses and Implants; D011817:Rabbits; D011859:Radiography; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; C022107:Bioglass