[The use of nimodipine in comatose patients with different types of cerebrovascular pathology].
The authors report on the use of nimodipine in 36 patients for coma due to severe cerebral (20 haemorrhagic, 2 ischaemic, 9 post-anoxic, 4 traumatic, 1 neoplastic) lesions. In addition to resuscitative therapy, all patients were given nimodipine per os, 60 mg every 4 hrs for 21 days. In all patients, survival, duration of the coma and degree of disability, according G.O.S., were evaluated. Decrease of mortality was highly significant, decrease of disability of surviving patients was significant if compared with comatose patients suffering from similar diseases, but not treated with nimodipine.
Alia
G
G
Servizio di Rianimazione e Terapia Intensiva, U.S.L. 58, Ospedale Civico di Palermo.
Mattaliano
A
A
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D002561:Cerebrovascular Disorders / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D002648:Child; D003128:Coma / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009553:Nimodipine / Q000627:therapeutic use*; D012151:Resuscitation
D009553:Nimodipine
Uso della nimodipina in pazienti comatosi affetti da patologie vascolari cerebrali di varia natura.