Compromise of the spinal canal in Proteus syndrome.
We report on 2 children with spinal stenosis and neurologic sequelae. They illustrate the 2 ways in which spinal compromise may develop in Proteus syndrome--vertebral anomalies or tumor infiltration. In one patient, spinal stenosis resulted from an angular kyphoscoliosis. In the other, cord compression resulted from infiltration of a paraspinal, intrathoracic angiolipoma.
Skovby
F
F
Department of Pediatrics, Rigshospitalet, Copenhagen, Denmark.
Graham
J M
JM
Sonne-Holm
S
S
Cohen
M M
MM
D018206:Angiolipoma / Q000150:complications / Q000473:pathology; D002648:Child; D006801:Humans; D007738:Kyphosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D016715:Proteus Syndrome / Q000150:complications* / Q000473:pathology; D011859:Radiography; D012600:Scoliosis / Q000150:complications; D013117:Spinal Cord Compression / Q000209:etiology; D013125:Spinal Neoplasms / Q000150:complications / Q000473:pathology; D013130:Spinal Stenosis / Q000000981:diagnostic imaging / Q000209:etiology*; D013131:Spine / Q000002:abnormalities