title: [Familial multiple bilateral carcinoma of the kidney: clinical strategy and surgical approach].
abstract: A case of familiar bilateral multicentric RCC in a young woman is an ideal model to evaluate preoperative and intraoperative diagnostic and surgical tools in order to achieve two distinct goals: the oncologic radicalness and the renal function preserved. Radical bilateral nephrectomy, the renal hypothermia by perfusion of both kidneys, the bench high resolution sonography of parenchyma, the choose of one kidney suitable for conservative surgery, the resection of suspect lesions with intraoperative pathology, the reconstructive bench surgery, the autotransplantation, are the steps accurately performed with particular concern to eradication of all the tumoral lesions present in the kidneys. The results confirm that renal function has been preserved with this method. Radicalness should be appointed by a longlasting follow up. However, as it is discussed, conservative surgery, when accurately performed can give results not different from radical demolitive surgery. In this paper tools to improve diagnostic and therapeutic methods are described in order to increase the diagnostic accuracy and the therapeutic efficacy. The possibility that this multiple RCC can be a part of the abnormalities occurring in the Von Hippel-Lindau syndrome does not change the surgical approach, being the RCC the worst prognostic factor of the syndrome.
authors.affiliation: Unità Operativa di Urologia, USSL n. 8, Ospedale di Busto Arsizio, VA.
authors.forename: A
authors.initials: A
authors.lastname: Mandressi
authors.forename: C
authors.initials: C
authors.lastname: Buizza
authors.forename: A
authors.initials: A
authors.lastname: Assi
authors.forename: L
authors.initials: L
authors.lastname: Solbiati
authors.forename: D
authors.initials: D
authors.lastname: Antonelli
authors.forename: P
authors.initials: P
authors.lastname: Allaria
authors.forename: S
authors.initials: S
authors.lastname: Greco
authors.forename: V
authors.initials: V
authors.lastname: Cioffi
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D014057:Tomography, X-Ray Computed
vernacular_title: Carcinoma renale bilaterale multiplo familiare: strategia clinica e tattica chirurgica.