Evaluation of the efficacy of interdental cleaning devices. How to design a clinical study.
A review of the literature was made, focusing on experimental designs used in clinical studies for assessment of the efficacy of interdental cleaning aids with regard to plaque removal and the prevention of caries and gingivitis. After careful consideration of the pros and cons of published procedures, an experimental design for such studies is proposed.
Kleisner
J
J
Department of Preventive Dentistry, Periodontology and Cardiology, University Dental Institute, Zurich, Switzerland.
Imfeld
T
T
D002986:Clinical Trials as Topic / Q000379:methods*; D015986:Confounding Factors, Epidemiologic; D003742:Dental Devices, Home Care; D003773:Dental Plaque / Q000628:therapy*; D005069:Evaluation Studies as Topic; D006801:Humans; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012107:Research Design