Invasive pulmonary aspergillosis and nocardiosis in an immunocompromised host.
A case of invasive pulmonary aspergillosis and nocardiosis following high dose prolonged steroid therapy given for suspected rapidly progressive glomerulonephritis is reported. A favourable response was achieved with a combination of amphotericin B and cotrimoxazole. A high index of suspicion and aggressive investigations are necessary for confirmation of diagnosis and early institution of appropriate therapy.
Varma
P P
PP
Department of Nephrology and Internal Medicine, PGIMER, Chandigarh.
Chugh
S
S
Gupta
K L
KL
Sakhuja
V
V
Chugh
K S
KS
D000666:Amphotericin B / Q000627:therapeutic use; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D005921:Glomerulonephritis / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects*; D008875:Middle Aged; D009617:Nocardia Infections / Q000150:complications* / Q000188:drug therapy; D011859:Radiography; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000666:Amphotericin B; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D008775:Methylprednisolone