title: Canalicular infection caused by Actinomyces.
abstract: We present 7 cases of canalicular involvement with Actinomyces collected over a 5-year period. All patients had involvement of one canaliculus, upper or lower, with lacrimal drainage patent to syringing. Curettings obtained by incising the involved canaliculi yielded Actinomyces species (5 cases) and Arachnia propionica (2 cases), typically in association with a mixed bacterial growth. Our results show that these patients often remain undiagnosed for months or even years, and are treated inappropriately for their recurrent symptoms. Despite sensitivity of Actinomyces to a broad spectrum of antibiotics, medical therapy alone does not eradicate the disease, and surgical evacuation of all concretions is essential to achieve a cure.
authors.affiliation: Royal Eye Hospital, Manchester, UK.
authors.forename: I
authors.initials: I
authors.lastname: Hussain
authors.forename: R E
authors.initials: RE
authors.lastname: Bonshek
authors.forename: K
authors.initials: K
authors.lastname: Loudon
authors.forename: M
authors.initials: M
authors.lastname: Armstrong
authors.forename: A B
authors.initials: AB
authors.lastname: Tullo
mesh_terms: D000196:Actinomycosis / Q000150:complications*; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003607:Dacryocystitis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000935:Antifungal Agents