title: Management of cytogenetic data in multi-center leukemia trials.
abstract: This paper provides methods for storing and retrieving cytogenetics data, which must reside jointly in a reference laboratory and in a data co-ordinating center. The major piece of data is the character string that uses the International System for Human Cytogenetic Nomenclature. Simple and complex data retrieval, using Statistical Analysis System (SAS) functions INDEX and SUBSTR, are illustrated. Use of the methods of this paper can save considerable costs in setting up cytogenetic data systems compared with other proposed systems which have come to the authors' attention.
authors.affiliation: POG Statistical Office, University of Florida, Gainesville.
authors.forename: J J
authors.initials: JJ
authors.lastname: Shuster
authors.forename: A J
authors.initials: AJ
authors.lastname: Carroll
authors.forename: T A
authors.initials: TA
authors.lastname: Look
authors.forename: C H
authors.initials: CH
authors.lastname: Pui
authors.forename: V J
authors.initials: VJ
authors.lastname: Land
authors.forename: J
authors.initials: J
authors.lastname: Jackson
authors.forename: D J
authors.initials: DJ
authors.lastname: Pullen
authors.forename: C P
authors.initials: CP
authors.lastname: Steuber
authors.forename: W M
authors.initials: WM
authors.lastname: Crist
mesh_terms: D002648:Child; D002869:Chromosome Aberrations / Q000145:classification*; D025063:Chromosome Disorders; D003582:Cytogenetics; D003628:Database Management Systems; D001330:Electronic Data Processing; D006801:Humans; D007621:Karyotyping; D015337:Multicenter Studies as Topic; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000145:classification / Q000235:genetics*; D009626:Terminology as Topic