VP4 serotype of the Gottfried strain of porcine rotavirus.
The antigenic relationships of the VP4 serotype of porcine rotavirus Gottfried strain with other rotaviruses were determined by using antiserum to Gottfried VP4-baculovirus recombinant. This antiserum failed to react significantly with virus of serotypes P1A, P1B, P3, and OSU; however, it reacted with P2 strains. In the reciprocal assay, antiserum to VP4 of an asymptomatic strain (P2) failed to neutralize the Gottfried strain virus to a significant level. It thus appears that the Gottfried strain should be considered a subtype of P2.
Li
B
B
Epidemiology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
Gorziglia
M
M
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D001483:Base Sequence; D002213:Capsid / Q000235:genetics / Q000276:immunology*; D036022:Capsid Proteins; D006168:Guinea Pigs; D007106:Immune Sera / Q000276:immunology; D008969:Molecular Sequence Data; D009500:Neutralization Tests; D012401:Rotavirus / Q000145:classification / Q000276:immunology*; D012703:Serotyping; D013552:Swine / Q000382:microbiology*
D000911:Antibodies, Monoclonal; D036022:Capsid Proteins; D007106:Immune Sera; C060339:VP4 protein, Rotavirus