title: [Primary sclerosing cholangitis. Illustrated by an unselected hospital material].
abstract: During the period from 1985 to 1993 primary sclerosing cholangitis was diagnosed in 16 patients, five females and 11 males, mean age 43 years. 12 of the patients (75%) had inflammatory bowel disease. Among 262 patients with ulcerative colitis, cholangitis was found in ten, whereas the disease was diagnosed in only two (1.9%) of the 108 patients with Crohn's disease. In eight patients (50%) no progression of the cholangitis was observed. However, six patients (38%) died during the observation period, three 19% due to cholangiocarcinoma and one due to liver failure. Cholangiocarcinoma is frequently found in patients with primary sclerosing cholangitis. A mortality of 38% indicates a serious clinical course in many patients.
authors.affiliation: Medisinsk avdeling, Aker sykehus, Oslo.
authors.forename: P
authors.initials: P
authors.lastname: Utzon
authors.forename: E
authors.initials: E
authors.lastname: Aadland
authors.forename: H
authors.initials: H
authors.lastname: Bell
authors.forename: M
authors.initials: M
authors.lastname: Stiris
authors.forename: N
authors.initials: N
authors.lastname: Raknerud
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015209:Cholangitis, Sclerosing / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009664:Norway; D011379:Prognosis; D011859:Radiography
vernacular_title: Primaer skleroserende kolangitt. Belyst i et uselektert sykehusmateriale.