title: Growth and plasma zinc responses of young pigs fed pharmacologic levels of zinc.
abstract: Three trials were conducted to evaluate high levels of Zn addition from various Zn sources on growth performance and plasma Zn responses of 8-kg pigs. Zinc supplements were added to 20% CP starting diets (125 mg of Zn/kg) containing antibiotics. Trial 1 was done to evaluate plasma Zn responses of pigs fed three different feed-grade Zn sources: ZnO where supplemental Zn levels were 0, 250, 500, 1,000, 3,000, and 5,000 mg/kg; ZnSO4 at 1,500 or 2,500 mg of Zn/kg; and a zinc-lysine complex (Zn-Lys) at 1,500 or 2,500 mg of Zn/kg. Plasma Zn concentration as a function of supplemental Zn intake was fitted to a broken-line for ZnO data and to simple linear models for ZnSO4 and Zn-Lys data. For ZnO, plasma Zn did not increase until concentrations > 1,000 mg Zn/kg were fed. Above this level, plasma Zn increased linearly (P < .01) for all three sources of Zn, although slopes of the ZnO and Zn-Lys response curves were 56% (P < .05) and 110%, respectively, of the ZnSO4 slopes. In Trial 2, five diets were fed: basal, 3,000 and 5,000 mg of Zn/kg from ZnO, and 3,000 and 5,000 mg of Zn/kg from ZnSO4. Daily gain and daily feed intake were increased (P < .05) by ZnO addition, regardless of level, whereas ZnSO4 addition increased these performance indices only at the 3,000 mg of Zn/kg level of supplementation. Plasma Zn responses to ZnSO4 addition were almost double those of ZnO addition.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Animal Sciences, University of Illinois, Urbana 61801.
authors.forename: J D
authors.initials: JD
authors.lastname: Hahn
authors.forename: D H
authors.initials: DH
authors.lastname: Baker
mesh_terms: D000821:Animal Feed; D000818:Animals; D005260:Female; D005527:Food, Fortified; D008297:Male; D013431:Sulfates / Q000008:administration & dosage; D013552:Swine / Q000097:blood / Q000254:growth & development*; D015430:Weight Gain / Q000187:drug effects; D015032:Zinc / Q000008:administration & dosage* / Q000097:blood; D017967:Zinc Compounds / Q000008:administration & dosage; D015034:Zinc Oxide / Q000008:administration & dosage; D019287:Zinc Sulfate
chemical_list: D013431:Sulfates; D017967:Zinc Compounds; D019287:Zinc Sulfate; D015032:Zinc; D015034:Zinc Oxide