title: Glutaminase-like immunoreactivity in rat spinomesencephalic tract cells.
abstract: Retrograde transport of the fluorescent tracer Fluorogold was used in combination with immunohistochemical staining for the enzyme glutaminase to identify putative glutamatergic neurons belonging to the rat spinomesencephalic tract. Glutaminase-like staining in spinal projection neurons suggests that the relay of nociceptive information from the spinal cord to midbrain may involve the excitatory amino acid glutamate.
authors.affiliation: Department of Neurological Surgery, University of Miami, FL 33136.
authors.forename: R P
authors.initials: RP
authors.lastname: Yezierski
authors.forename: T
authors.initials: T
authors.lastname: Kaneko
authors.forename: K E
authors.initials: KE
authors.lastname: Miller
mesh_terms: D000818:Animals; D005456:Fluorescent Dyes; D005972:Glutaminase / Q000378:metabolism*; D007150:Immunohistochemistry; D008636:Mesencephalon / Q000166:cytology / Q000378:metabolism*; D009434:Neural Pathways / Q000166:cytology / Q000378:metabolism; D009474:Neurons / Q000378:metabolism / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000166:cytology / Q000378:metabolism*; D013266:Stilbamidines; D009435:Synaptic Transmission
chemical_list: C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D005456:Fluorescent Dyes; D013266:Stilbamidines; D005972:Glutaminase