A potentially artifact-free oral contrast agent for gastrointestinal MRI.
The combination of diamagnetic barium sulfate and superparamagnetic iron oxide (SPIO) in one suspension produces a macroscopic cancellation of positive and negative magnetic susceptibility components that can potentially eliminate susceptibility artifacts even with gradient echo pulse sequences. The relaxation properties that make the SPIO suspension a useful negative contrast agent are retained.
Liebig
T
T
Department of Radiology, University of Florida College of Medicine, Gainesville.
Stoupis
C
C
Ros
P R
PR
Ballinger
J R
JR
Briggs
R W
RW
D000284:Administration, Oral; D016477:Artifacts; D001466:Barium Sulfate / Q000008:administration & dosage; D003287:Contrast Media / Q000008:administration & dosage*; D004064:Digestive System / Q000033:anatomy & histology*; D052203:Ferrosoferric Oxide; D006801:Humans; D007501:Iron / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008961:Models, Structural; D010087:Oxides / Q000008:administration & dosage
D003287:Contrast Media; D010087:Oxides; D001466:Barium Sulfate; D007501:Iron; D052203:Ferrosoferric Oxide