Surgical treatment of induced peri-implantitis in the micro pig: clinical and histological analysis.
The purpose of this pilot study was to determine if lost osseous support adjacent to root form implants could be regenerated using a guided tissue regeneration technique. Three fixtures were placed in each edentulous mandibular bicuspid region of two micro pigs. A total of 6 fixtures were placed in each pig. Due to the presence of a pathologic condition, which was in no way related to the research, the results of one pig were not evaluated. Following osseointegration, peri-implantitis were induced by the use of ligatures and a soft diet. Three modalities of treatment were performed. Utilizing a surgical flap approach, one third of the fixtures (one per quadrant) were covered with expanded polytetrafluoroethylene (ePTFE) membrane and submerged under the soft tissue complex. The second group of fixtures were submerged under the soft tissue complex with no ePTFE membrane. The control fixtures along with their abutments were debrided and remained non-submerged. All fixtures were debrided using an air-abrasive polishing system. The osseous defects around the fixtures were measured from a fixed reference point at the time of surgery and after obtaining block sections.(ABSTRACT TRUNCATED AT 250 WORDS)
Singh
G
G
U.S. Army Dental Activity, Fort Leonard Wood, MO.
O'Neal
R B
RB
Brennan
W A
WA
Strong
S L
SL
Horner
J A
JA
Van Dyke
T E
TE
D016301:Alveolar Bone Loss / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D000818:Animals; D003758:Dental Implantation, Endosseous / Q000009:adverse effects*; D004195:Disease Models, Animal; D016557:Guided Tissue Regeneration, Periodontal; D008567:Membranes, Artificial; D016348:Osseointegration; D010518:Periodontitis / Q000473:pathology / Q000601:surgery*; D011138:Polytetrafluoroethylene; D013552:Swine; D013556:Swine, Miniature
D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene