title: Fish consumption, omega-3 fatty acids and the Mediterranean diet.
abstract: Many epidemiological, interventional and animal studies have concluded that consumption of polyunsaturated fatty acids of marine origin may confer special benefits in reducing cardiovascular heart disease (CHD) mortality rates by different physiological mechanisms. The available epidemiological data, although limited, suggest that a dietetic recommendation on the consumption of one or two servings per week (200-300 g = 2-4 g eicosapentaenoic acid) of cold water marine fish could lead to a reduction of the CHD risk. Nevertheless, there are important methodological shortcomings and contradictory findings in most published investigations on the omega-3 fatty acids. In order to assess the role of fish consumption in the Mediterranean diet, we have compared data on average fish and fatty fish consumption trends in some Mediterranean (Spain, Yugoslavia and Italy) and northern European (Norway, Denmark) countries. Fish consumption is not positively correlated with ischaemic heart disease mortality. That suggests that dietary factors other than fish, such as the lower meat consumption associated to the higher fish intake, or other differences of lifestyle have perhaps intervened, helping to explain the healthy nature of the Mediterranean diet.
authors.affiliation: Unit of Preventive Medicine, School of Medicine, University of Barcelona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: García-Closas
authors.forename: L
authors.initials: L
authors.lastname: Serra-Majem
authors.forename: R
authors.initials: R
authors.lastname: Segura
mesh_terms: D000818:Animals; D003327:Coronary Disease / Q000097:blood / Q000209:etiology / Q000378:metabolism / Q000401:mortality*; D003718:Denmark / Q000453:epidemiology; D004032:Diet; D004034:Diet Surveys; D015777:Eicosanoids / Q000378:metabolism; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage* / Q000494:pharmacology; D005340:Fibrinogen / Q000032:analysis / Q000187:drug effects; D005342:Fibrinolysis / Q000187:drug effects; D005399:Fishes; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008019:Life Style; D008074:Lipoproteins / Q000187:drug effects / Q000378:metabolism; D008460:Meat; D009664:Norway / Q000453:epidemiology; D011159:Population Surveillance; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D015022:Yugoslavia / Q000453:epidemiology
chemical_list: D015777:Eicosanoids; D015525:Fatty Acids, Omega-3; D008074:Lipoproteins; D005340:Fibrinogen