Effects of carotenoids on cells.
When added to cells, carotenoids display a variety of properties, including inhibition of mutagenesis, genotoxicity, malignant transformation, and growth of tumor cells. In addition, carotenoids increase cell-cell communication, and may have direct effects as cellular antioxidants.
Krinsky
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Department of Biochemistry, Tufts University School of Medicine, Boston, MA 02111-1837.
D000818:Animals; D016587:Antimutagenic Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002338:Carotenoids / Q000494:pharmacology*; D002450:Cell Communication / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002468:Cell Physiological Phenomena; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D002477:Cells / Q000166:cytology / Q000187:drug effects*; D006801:Humans; D016296:Mutagenesis; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity; D012854:Sister Chromatid Exchange / Q000187:drug effects; D014407:Tumor Cells, Cultured
D016587:Antimutagenic Agents; D000975:Antioxidants; D009153:Mutagens; D002338:Carotenoids