[Adrenal hormones in the formation of atherosclerotic precursors in adolescents with primary arterial hypertension].
The components of blood lipid spectrum (total cholesterol, triglycerides and high density lipoprotein cholesterol) were studied in 131 adolescents (12-18 years old) with primary arterial hypertension at various levels of adrenal hormones (hydrocortisone and aldosterone) and blood plasma renin activity. The optimal ratio of lipid components in blood was detected if concentrations of adrenal hormones and blood plasma renin activity were low. Hyperfunction of the adrenal cortex in teen-agers contributed both to the development of hypertension and to atherosclerotic changes in vessels. This suggests that definite forms of hypertension occurred in adults, with specific impairments in the metabolism of blood serum lipids, were developed during the juvenile age.
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D000293:Adolescent; D000450:Aldosterone / Q000097:blood / Q000502:physiology*; D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000502:physiology*; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D012083:Renin / Q000097:blood*; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D014280:Triglycerides; D000450:Aldosterone; D002784:Cholesterol; D012083:Renin; D006854:Hydrocortisone
Gormony nadpochechnikov v formirovanii predvestnikov ateroskleroza u podrostkov s pervichnoĭ arterial'noĭ gipertenzieĭ.