6-Azasteroids: potent dual inhibitors of human type 1 and 2 steroid 5 alpha-reductase.
Frye
S V
SV
Glaxo Inc. Research Institute, Research Triangle Park, North Carolina 27709.
Haffner
C D
CD
Maloney
P R
PR
Mook
R A
RA
Dorsey
G F
GF
Hiner
R N
RN
Batchelor
K W
KW
Bramson
H N
HN
Stuart
J D
JD
Schweiker
S L
SL
D058891:5-alpha Reductase Inhibitors; D000818:Animals; D001378:Azasteroids / Q000138:chemical synthesis* / Q000494:pharmacology; D016367:Baculoviridae / Q000235:genetics; D002460:Cell Line; D013196:Dihydrotestosterone / Q000378:metabolism; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D008297:Male; D009036:Moths; D009919:Orchiectomy; D051381:Rats; D017207:Rats, Sprague-Dawley; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors; D013739:Testosterone / Q000378:metabolism; D014162:Transfection
D058891:5-alpha Reductase Inhibitors; D001378:Azasteroids; D007527:Isoenzymes; D011994:Recombinant Proteins; D013196:Dihydrotestosterone; D013739:Testosterone