A dimensional and categorical approach to the symptomatology of recent-onset schizophrenia.
Sixty-five patients with recent-onset schizophrenia were assessed with two widely used symptom scales, the Brief Psychiatric Rating Scale-Expanded (BPRS-E) and the Psychiatric Assessment Scale (Manchester scale). Principal components analysis of the BPRS-E scores yielded a four-dimensional structure: positive symptoms, negative symptoms, disorganization, and depression. With the Psychiatric Assessment Scale, three dimensions were found: the positive symptoms (delusions, hallucinations) and disorganization (incoherence) appeared in one dimension. A categorical analysis resulted in predominantly positive, negative, and disorganized clusters, but more than half of the sample could not be allocated to any of these groups.
Van der Does
A J
AJ
Department of Psychiatry, Leiden University, The Netherlands.
Linszen
D H
DH
Dingemans
P M
PM
Nugter
M A
MA
Scholte
W F
WF
D000293:Adolescent; D000328:Adult; D016000:Cluster Analysis; D003702:Delusions / Q000145:classification / Q000175:diagnosis; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis; D016002:Discriminant Analysis; D005163:Factor Analysis, Statistical; D005260:Female; D006212:Hallucinations / Q000145:classification / Q000175:diagnosis; D006760:Hospitalization; D006801:Humans; D008297:Male; D008960:Models, Psychological; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D012559:Schizophrenia / Q000145:classification / Q000175:diagnosis*; D012565:Schizophrenic Psychology