title: Methods for ablating neurons.
abstract: This past year, laser ablation has been applied to investigations of neuromuscular connectivity in Drosophila, neuronal function in nematode, and mammalian central nervous system development. Ablation by targeted gene expression has been refined and applied to questions of neural development. Chromophore-assisted laser inactivation has been used to demonstrate distinct functions for two proteins during grasshopper neural development.
authors.affiliation: Harvard University, Cambridge.
authors.forename: E M
authors.initials: EM
authors.lastname: Shah
authors.forename: D G
authors.initials: DG
authors.lastname: Jay
mesh_terms: D000818:Animals; D002469:Cell Separation; D006801:Humans; D009462:Neurology / Q000379:methods; D009474:Neurons; D013048:Specimen Handling / Q000379:methods*