title: Introduction and history of the use of electroencephalography in animal drug studies.
abstract: A brief review of the development and the state-of-the-art of EEG methods used to study drug effects is presented. Classification systems based on drug effects in animals kept awake artificially, and based on drug effects on the sleep-wake state duration and distribution are discussed. It is concluded that the techniques are there and the time is ripe to develop animal EEG-based drug classification systems with high predictive ability.
authors.affiliation: Research and Development Department, Pharmaceuticals Division Ciba-Geigy Ltd., Basel, Switzerland.
authors.forename: H
authors.initials: H
authors.lastname: van Riezen
authors.forename: A F
authors.initials: AF
authors.lastname: Glatt
mesh_terms: D000818:Animals; D004569:Electroencephalography / Q000187:drug effects / Q000266:history*; D049673:History, 20th Century; D011619:Psychotropic Drugs / Q000145:classification / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects
chemical_list: D011619:Psychotropic Drugs