title: Tooth sensitivity: mechanisms and management.
abstract: Tooth sensitivity is a common complaint encountered in clinical practice. Exposed superficial dentin is free of nerve endings, yet sensitive. Experimental evidence indicates that stimuli, such as probing the dentin surface and air blasts, induce fluid movements in the dentinal tubules and these fluid movements, in turn, activate the intradental nerves. The condition of the dentin surface is critically important in allowing this process. In addition, the internal environment of the pulp may influence nerve excitability. Therapies for tooth sensitivity include both agents that obstruct the dentinal tubules and agents that can decrease the excitability of the intradental nerves. The exact treatment used depends on the etiology of the individual's problem and the extent of dentinal tissue damage.
authors.affiliation: Division of Endodontics, School of Dental and Oral Surgery-Columbia University, New York.
authors.forename: K
authors.initials: K
authors.lastname: Markowitz
mesh_terms: D000818:Animals; D001826:Body Fluids; D002412:Cations; D003782:Dental Pulp / Q000098:blood supply / Q000294:innervation; D003804:Dentin / Q000648:ultrastructure; D003807:Dentin Sensitivity / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D006874:Hydrostatic Pressure; D008564:Membrane Potentials; D009566:Nitrates / Q000627:therapeutic use; D011188:Potassium / Q000378:metabolism; D017680:Potassium Compounds / Q000627:therapeutic use; D013324:Strontium / Q000627:therapeutic use; D014098:Toothache / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D002412:Cations; D009566:Nitrates; D017680:Potassium Compounds; C025700:strontium chloride; C023844:potassium nitrate; D011188:Potassium; D013324:Strontium