title: Blood and hepatic glutathione in linamarin fed rats.
abstract: Female Sprague Dawley rats were fed 5 mg linamarin daily for 10 days. Reduced glutathione (GSH) levels in blood and liver of experimental rats were analysed. The results showed an increase of 45% and 33% glutathione levels in blood and liver respectively in experimental rats. This alteration in glutathione levels could be most likely either due to increased hepatic biosynthesis or as a consequence of decreased peripheral utilization which might be appreciated due to hypothyroidal status induced by linamarin feeding.
authors.affiliation: Institute of Nuclear Medicine & Allied Sciences, Delhi, India.
authors.forename: B P
authors.initials: BP
authors.lastname: Uniyal
authors.forename: L R
authors.initials: LR
authors.lastname: Singh
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherjee
mesh_terms: D000818:Animals; D005260:Female; D005978:Glutathione / Q000097:blood / Q000378:metabolism*; D007037:Hypothyroidism / Q000209:etiology; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D002365:Manihot / Q000633:toxicity; D009570:Nitriles / Q000633:toxicity*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D009570:Nitriles; D005978:Glutathione; C005091:linamarin