Translocation (12;13) in a case of infantile fibrosarcoma.
Cytogenetic analysis of an infantile fibrosarcoma showed the presence of a t(12;13) and numerical changes of chromosomes 15 and 20. Until now only non-random gain or loss of total chromosomes as well as one case with a deletion at 17p have been reported for this kind of tumor. This report represents the first cytogenetic description of an aggressive infantile fibrosarcoma with a translocation.
Strehl
S
S
CCRI, Children's Cancer Research Institute, Vienna, Austria.
Ladenstein
R
R
Wrba
F
F
Salzer-Kuntschik
M
M
Gadner
H
H
Ambros
P F
PF
D002881:Chromosomes, Human, Pair 12; D002882:Chromosomes, Human, Pair 13; D005260:Female; D005354:Fibrosarcoma / Q000151:congenital* / Q000235:genetics*; D006801:Humans; D007223:Infant; D013899:Thoracic Neoplasms / Q000151:congenital / Q000235:genetics; D014178:Translocation, Genetic