Extension of the cleft lip phenotype: the subepithelial cleft.
We present a previously undescribed occult malformation of the upper lip manifest by discontinuity of the orbicularis oris muscle. The relationship of this defect to our current concept of abnormal maxillary process development is discussed along with a proposal to extend the cleft lip phenotype.
Martin
R A
RA
Department of Pediatrics, University of California Irvine Medical Center, Orange 92613-1491.
Jones
K L
KL
Benirschke
K
K
D002971:Cleft Lip / Q000196:embryology / Q000473:pathology*; D004848:Epithelium / Q000002:abnormalities / Q000196:embryology; D005865:Gestational Age; D006801:Humans; D008046:Lip / Q000002:abnormalities / Q000196:embryology; D008648:Mesoderm / Q000473:pathology; D009132:Muscles / Q000002:abnormalities / Q000196:embryology; D010641:Phenotype