title: Causes of increasing pericardial pressure in experimental cardiac tamponade induced by ventricular perforation.
abstract: It has been shown that the intravenous infusion of saline solution in a dog with stabilized cardiac tamponade produced an increase in pericardial pressure. To demonstrate that this pressure increase is the result of bleeding into the pericardial sac, an experimental study was conducted, consisting of the injection of red cells marked with 51Cr during the intravenous infusion of saline solution in dogs with and without progressive tamponade. The results showed that in the dogs without progressive tamponade, both the pericardial pressure and the red cell count in the pericardial cavity remained stable during the infusion of saline solution, whereas in dogs with progressive tamponade, the numbers of marked cells and the pericardial pressure increased significantly, following a similar pattern.
authors.affiliation: Department of Surgery, Faculty of Medicine, University of Concepción, Chile.
authors.forename: J
authors.initials: J
authors.lastname: Pierart
authors.forename: A
authors.initials: A
authors.lastname: Gyhra
authors.forename: P
authors.initials: P
authors.lastname: Torres
authors.forename: L
authors.initials: L
authors.lastname: Cid
authors.forename: F
authors.initials: F
authors.lastname: Rocha
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002305:Cardiac Tamponade / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D002860:Chromium Radioisotopes; D004195:Disease Models, Animal; D004285:Dogs; D004912:Erythrocytes; D006335:Heart Injuries / Q000150:complications*; D006352:Heart Ventricles / Q000293:injuries; D007262:Infusions, Intravenous; D016014:Linear Models; D010490:Pericardial Effusion / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D010496:Pericardium; D012965:Sodium Chloride / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D002860:Chromium Radioisotopes; D012965:Sodium Chloride