title: Anxious and non-anxious bipolar disorder.
abstract: Eighty-one outpatients with bipolar disorder (BD) were grouped by SADS anxiety symptom scores (high vs. low) or diagnosis of generalized anxiety disorder, and/or panic disorder. BD patients with high anxiety scores were more likely to have suicidal behaviour (44% vs. 19%), alcohol abuse (28% vs. 6%), cyclothymia (44% vs. 21%) and an anxiety disorder (56% vs. 25%) with a trend toward lithium non-responsiveness. Diagnosis of an anxiety disorder was related only to high anxiety and lower GAS scores. Thus, anxiety may have similar clinical relevance in BD as it does in unipolar patients.
authors.affiliation: Mood Disorders Program, Clarke Institute of Psychiatry, Toronto, Canada.
authors.forename: L T
authors.initials: LT
authors.lastname: Young
authors.forename: R G
authors.initials: RG
authors.lastname: Cooke
authors.forename: J C
authors.initials: JC
authors.lastname: Robb
authors.forename: A J
authors.initials: AJ
authors.lastname: Levitt
authors.forename: R T
authors.initials: RT
authors.lastname: Joffe
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D008094:Lithium