title: VP4 serotype of the Gottfried strain of porcine rotavirus.
abstract: The antigenic relationships of the VP4 serotype of porcine rotavirus Gottfried strain with other rotaviruses were determined by using antiserum to Gottfried VP4-baculovirus recombinant. This antiserum failed to react significantly with virus of serotypes P1A, P1B, P3, and OSU; however, it reacted with P2 strains. In the reciprocal assay, antiserum to VP4 of an asymptomatic strain (P2) failed to neutralize the Gottfried strain virus to a significant level. It thus appears that the Gottfried strain should be considered a subtype of P2.
authors.affiliation: Epidemiology Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
authors.forename: B
authors.initials: B
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Gorziglia
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D001483:Base Sequence; D002213:Capsid / Q000235:genetics / Q000276:immunology*; D036022:Capsid Proteins; D006168:Guinea Pigs; D007106:Immune Sera / Q000276:immunology; D008969:Molecular Sequence Data; D009500:Neutralization Tests; D012401:Rotavirus / Q000145:classification / Q000276:immunology*; D012703:Serotyping; D013552:Swine / Q000382:microbiology*
chemical_list: D000911:Antibodies, Monoclonal; D036022:Capsid Proteins; D007106:Immune Sera; C060339:VP4 protein, Rotavirus