[A comparative evaluation of the hemodynamic parameters and of the vascular adrenergic reactions in the skeletal muscles of normo- and hypertensive rats].
In normotensive and hypertonic rats of the WKY and SHR lines, resp., a significant difference between values of the resistance against blood flow was found: it was 1.34 and 1.5-fold greater in the latters for the regimens of constant perfusion pressure and stabilised blood flow, resp. The capillary hydrostatic pressure and the capillary filtration coefficient did not differ significantly in both groups. The increase of the vascular resistance in skeletal muscles in response to noradrenaline administration was significantly lesser in the hypertensive rats. The data obtained suggest that the extent of distensibility of the vascular bed by the blood pressure can be a determining factor of the adrenergic shift of vascular resistance in both groups of animals.
Matchanov
A T
AT
Shustova
N Ia
NIa
Shalenkov
V F
VF
Dvoretskiĭ
D P
DP
D000818:Animals; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D009132:Muscles / Q000098:blood supply*; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D011941:Receptors, Adrenergic / Q000502:physiology*; D014655:Vascular Resistance / Q000502:physiology
D011941:Receptors, Adrenergic
Sravnitel'naia otsenka parametrov gemodinamiki i sosudistykh adrenergicheskikh reaktsiĭ v skeletnykh myshtsakh u normo- i gipertenzivnykh krys.