[Continuous intravenous antibiotic home treatment in 11 patients with cystic fibrosis in The Northern Netherlands].
OBJECTIVE
Assessment of intravenous home treatment of respiratory infections of cystic fibrosis (CF) patients.


METHODS
Provinces Groningen, Drente, Friesland and Overijssel.


METHODS
Open study.


METHODS
Eleven CF patients, aged 10 to 28 years participated. Thirty episodes of home i.v. treatment with antibiotics were arranged. Differences in vital capacity (VC) and forced expiratory volume in one second (FEV1) and in body weight before and after treatment were compared with the same variables obtained during hospitalisation in the year before they were treated at home. Adverse events during home treatment were recorded.


RESULTS
No differences were noted in changes in VC, FEV1 and body weight between home and hospital treatments. During 30 episodes of home treatment a new intravenous catheter had to be implanted only twice.


CONCLUSIONS
In these 11 patients, intravenous treatment of respiratory infections at home was as efficacious as in hospital. No serious adverse events were observed.
van Aalderen
W M
WM
Afd. Kinderlongziekten, Academisch Ziekenhuis, Beatrix Kinderkliniek, Groningen.
Mannes
G P
GP
van Bommel
G
G
Voorthuis
I
I
Bosma
E
E
Heymans
H S
HS
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications*; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D006699:Home Care Services / Q000458:organization & administration*; D006801:Humans; D007260:Infusion Pumps; D009426:Netherlands; D010290:Parents / Q000193:education; D010353:Patient Education as Topic; D015397:Program Evaluation; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000150:complications / Q000188:drug therapy*
D000900:Anti-Bacterial Agents
Continue intraveneuze thuisbehandeling met antibiotica van luchtweginfecties bij 11 patiënten met cystische fibrose in Noord-Nederland.