[Genetic analysis of the resting EEG parameters of schizophrenics and their relatives].
The heritability of the resting EEG parameters was studied in 45 schizophrenic families. In offspring--parent pairs (N = 94) and sibs pairs (N = 27) high correlation of average power values of frequency bands between relatives was found (r > 0.5 for alpha and beta power; r 0.2 to 0.45 for delta and theta power in different electrode placement). Linear discriminate functions (LDF) to separate 1) a control group (N = 20) from healthy relatives (N = 46), 2) control group from relatives with borderline pathology (N = 36) and 3) healthy relatives from relatives with borderline pathology were obtained. True classification is possible in 79%, 81% and 76% cases, heritability coefficients of LDF are 47.7, 64.6 and 57.1% respectively.
Trubnikov
V I
VI
Uvarova
L G
LG
Orlova
V A
VA
D000293:Adolescent; D000328:Adult; D000368:Aged; D016002:Discriminant Analysis; D004569:Electroencephalography; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012146:Rest; D012559:Schizophrenia / Q000235:genetics* / Q000503:physiopathology
Geneticheskiĭ analiz pokazateleĭ EEG pokoia bol'nykh shizofrenieĭ i ikh rodstvennikov.