title: [Gonadotropin receptor system and its signal transduction pathway].
abstract: Recent advances in genetic studies have elucidated structure of gonadotropin receptors. This transmembrane receptor contains seven transmembrane domains and induces multiple biological changes in granulosa/theca cells resulting in follicular maturation in women. The signal transduction involves G protein mediated systems, cAMP mediated systems and phospholipase C systems. This paper reviews recent advances in gonadotropin receptor system and its signal transduction pathway.
authors.affiliation: Department of Obstetrics and Gynecology, Nihon University School of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Takami
authors.forename: H
authors.initials: H
authors.lastname: Sakamoto
authors.forename: K
authors.initials: K
authors.lastname: Satoh
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism; D005260:Female; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D011967:Receptors, Gonadotropin / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction; D010738:Type C Phospholipases / Q000378:metabolism
chemical_list: D011967:Receptors, Gonadotropin; D000242:Cyclic AMP; D010738:Type C Phospholipases; D019204:GTP-Binding Proteins