[Sideroses of alveolar macrophages. Analysis of a continuous series of 360 bronchoalveolar lavages].
360 consecutive bronchoalveolar lavage fluids (BAL) were studied using semi-quantitative method described by GOLDE (GOLDE score). 44 hemosiderosis were detected (12%). Most of them corresponded to massive alveolar hemorrhage (AH). Depending on pathological contexts, we distinguished three main groups of AH frequency: a group of high frequency (around 40%), an intermediate group (10%) and a low frequency group with less than 5%. Matching cytological results with clinical and radiological data, revealed that AH was often too late diagnosed because inconstancy of typical clinical and radiological signs. Even with a variable prognosis related to different physiopathological mechanisms, AH evolution is unpredictable. The authors suggest thus BAL cytological examination may systematically include a research of hemosiderosis in AH high frequency groups.
Moumouni
H
H
Laboratoire de Pathologie Cellulaire, CHR Bretonneau, Tours, France.
Lamotte
F
F
Anthonioz
P
P
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D002648:Child; D002675:Child, Preschool; D006331:Heart Diseases / Q000150:complications; D006402:Hematologic Diseases / Q000150:complications; D006470:Hemorrhage / Q000150:complications / Q000175:diagnosis*; D006486:Hemosiderosis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007674:Kidney Diseases / Q000150:complications; D016676:Macrophages, Alveolar / Q000737:chemistry*; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced / Q000150:complications
Sidéroses ds macrophages alvéolaires. Analyse d'une série continue de 360 lavages broncho-alvéolaires.