[An experimental study of chemical necrectomy in chemical injuries of the skin].
The authors studied experimentally the morphological changes of injuries and the surrounding areas after a skin chemical injury caused by sodium hydroxide, sulphuric acid and chlorhydric acid under the influence of acidic necrolytics--40% benzoic acid and 40% salycilic acid in unguentus. The necrolytics are applied on the injured areas immediately upon getting the wound or on the 4th day thereafter, while the morphological study is carried out after getting off the necrosis. It has been established that the necrolysis in the case of sodium hydroxide was not effected by the 28th day. The processes in the tissues upon acidic injuries do not differ from the spontaneous healing process.
Troshev
K
K
Markov
D
D
Skerlev
M
M
D000818:Animals; D001565:Benzoates / Q000008:administration & dosage*; D019817:Benzoic Acid; D002057:Burns, Chemical / Q000188:drug therapy* / Q000473:pathology; D003646:Debridement / Q000379:methods*; D004353:Drug Evaluation, Preclinical; D009336:Necrosis; D009824:Ointments; D012459:Salicylates / Q000008:administration & dosage*; D020156:Salicylic Acid; D012867:Skin / Q000187:drug effects / Q000473:pathology; D013997:Time Factors
D001565:Benzoates; D009824:Ointments; D012459:Salicylates; D019817:Benzoic Acid; D020156:Salicylic Acid
Eksperimentalno prouchvane na khimicheskata nekrektomiia pri khimicheski uvrezhdaniia na kozhata.