Efficacy of methylprednisolone administration in a case of continuous abnormal muscle activity syndrome.
We report a 20-year-old woman with continuous abnormal muscle activity syndrome in which pharmacological blockade of different sites of the motor unit demonstrates a peripheral nerve origin for the abnormal muscle activity. The case showed no markers of autoimmune disease. A rapid recovery after high dose i.v. methylprednisolone was observed supporting the hypothesis of an autoimmune pathogenesis.
Jalil
P
P
Servicio de Neurologia, Hospital Dr. Sotero del Rio, Chile.
Frenkel
C
C
Guiloff
R
R
Gajewski
C
C
Vergara
F
F
D000328:Adult; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use*; D009119:Muscle Contraction; D009135:Muscular Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D010525:Peripheral Nerves / Q000503:physiopathology*; D016896:Treatment Outcome
D008775:Methylprednisolone