title: [Amiodarone-induced skin pigmentation].
abstract: Amiodarone (Cordarone) is used in the treatment of cardiac arrhythmias. A blue-grey skin pigmentation appears after long term use or a high concentration of amiodarone. Two cases are described. Histopathological findings of skin punch biopsies from the face showed collections of yellow-brown granula pigment within histiocytes throughout the dermis. Sunlight initiates accumulation of the pigment. It is recommended to use sunprotection to avoid the pigmentation.
authors.affiliation: Patologisk afdeling, Hvidovre Hospital, København.
authors.forename: E
authors.initials: E
authors.lastname: Balslev
authors.forename: G
authors.initials: G
authors.lastname: Heydenreich
authors.forename: S E
authors.initials: SE
authors.lastname: Jensen
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology*; D012880:Skin Pigmentation / Q000187:drug effects* / Q000528:radiation effects; D013472:Sunlight / Q000009:adverse effects
chemical_list: D000638:Amiodarone
vernacular_title: Amiodaroninduceret hudpigmentering.