title: Assignment of 22 loci in the rat by somatic hybrid and linkage analysis.
abstract: Twenty structural genes and two unique anonymous DNA fragments have been mapped in the rat (Rattus norvegicus) with a panel of mouse x rat hybrids and linkage analysis. Ten of the 20 autosomes are represented by at least one of these markers. A new syntenic relationship among rat Chromosome (Chr) 16, mouse Chr 14, and human Chr 10q was established. Results of this study further support the extensive conservation of synteny between the rat and mouse and, to a lesser degree, between rat and human.
authors.affiliation: Fox Chase Cancer Center, Department of Surgical Oncology, Philadelphia, Pennsylvania 19111.
authors.forename: R S
authors.initials: RS
authors.lastname: Yeung
authors.forename: O
authors.initials: O
authors.lastname: Hino
authors.forename: M
authors.initials: M
authors.lastname: Vilensky
authors.forename: K
authors.initials: K
authors.lastname: Buetow
authors.forename: C
authors.initials: C
authors.lastname: Szpirer
authors.forename: J
authors.initials: J
authors.lastname: Szpirer
authors.forename: K
authors.initials: K
authors.lastname: Klinga-Levan
authors.forename: G
authors.initials: G
authors.lastname: Levan
authors.forename: A G
authors.initials: AG
authors.lastname: Knudson
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping / Q000379:methods*; D003433:Crosses, Genetic; D005260:Female; D005796:Genes; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D008297:Male; D051379:Mice; D051381:Rats
chemical_list: D005819:Genetic Markers