title: Method to reduce blur distortion from EEG's using a realistic head model.
abstract: A mathematical procedure, which we call "Deblurring," was developed to reduce spatial blur distortion of scalp-recorded brain potentials due to transmission through the skull and other tissues. Deblurring estimates potentials at the superficial cerebral cortical surface from EEG's recorded at the scalp using a finite element model of each subject's scalp, skull and cortical surface constructed from their magnetic resonance images (MRI's). Simulations indicate that Deblurring is numerically stable, while a comparison of deblurred data with a direct cortical recording from a neurosurgery patient suggests that the procedure is valid. Application of Deblurring to somatosensory evoked potential data recorded at 124 scalp sites suggests that the method produces a dramatic improvement in spatial detail, and merits further development.
authors.affiliation: EEG Systems Laboratory and SAM Technology, San Francisco, CA 94107.
authors.forename: J
authors.initials: J
authors.lastname: Le
authors.forename: A
authors.initials: A
authors.lastname: Gevins
mesh_terms: D000328:Adult; D001931:Brain Mapping; D003198:Computer Simulation; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008953:Models, Anatomic; D012016:Reference Values; D012886:Skull / Q000033:anatomy & histology