title: Therapeutic effects of flunitrazepam in dystonias and torticollis. Preliminary communication.
abstract: A new form of clinical treatment is proposed for dystonias and torticollis using flunitrazepam (FN), a powerful agonist of all benzodiazepine receptors of GABA neurons. FN has a specific effect in dystonic patients, specially those in which the hypnotic effect of this drug is absent or diminished, thus suggesting the existence of two different neurochemical categories of dystonias.
authors.affiliation: Department of Neurology, Hospital das Clínicas, University of São Paulo Medical School (FMUSP), Brasil.
authors.forename: R
authors.initials: R
authors.lastname: Marino Júnior
authors.forename: R
authors.initials: R
authors.lastname: Benabou
authors.forename: S
authors.initials: S
authors.lastname: Benabou
mesh_terms: D004421:Dystonia / Q000188:drug therapy*; D005260:Female; D005445:Flunitrazepam / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D014103:Torticollis / Q000188:drug therapy*
chemical_list: D005445:Flunitrazepam