title: Reflex seizures as initial manifestations of systemic lupus erythematosus in childhood.
abstract: We report a 10-year-old girl with reflex seizures characterized by visual and acoustic hallucinations, induced by visual and acoustic stimulations. The EEG showed atypical spike-wave discharges on the left temporo-occipital area, markedly activated by visual and acoustic stimuli (intermittent light, pattern-reversal stimulation and monoaural right pure tone). The patient was treated with carbamazepine and seizure stopped within 7 months. After 10 months from the start of the therapy she developed signs of systemic lupus erythematosus.
authors.affiliation: Dipartimento di Scienze Neurologiche e Psichiatriche dell'Età Evolutiva, Università La Sapienza, Roma, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Brinciotti
authors.forename: G
authors.initials: G
authors.lastname: Ferrucci
authors.forename: G
authors.initials: G
authors.lastname: Trasatti
authors.forename: R
authors.initials: R
authors.lastname: Priori
authors.forename: E
authors.initials: E
authors.lastname: Squilloni
authors.forename: G
authors.initials: G
authors.lastname: Valesini
mesh_terms: D000161:Acoustic Stimulation; D002220:Carbamazepine / Q000627:therapeutic use; D002648:Child; D005072:Evoked Potentials, Auditory / Q000502:physiology; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D010775:Photic Stimulation; D012018:Reflex / Q000502:physiology*; D012022:Reflex, Acoustic / Q000502:physiology*; D012640:Seizures / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D002220:Carbamazepine