Changes in cortical field potentials during learning processes of go/no-go reaction time hand movement with tone discrimination in the monkey.
Field potentials were recorded with electrodes implanted in various cortical areas while a monkey acquired a task of go/no-go reaction time hand movement with discrimination between tone stimuli of different frequencies. After a few weeks of training, a surface-negative, depth-positive (s-N, d-P) potential (no-go potential) emerged in the dorsal bank of the principal sulcus. As the potential increased in size in 1-3 months, the monkey gradually discriminated between go and no-go stimuli. The no-go potential is considered to be related to judgement not to move and suppression of motor execution. In the superior temporal gyrus, a s-N, d-P potential at a shorter latency than the no-go potential augmented in size on both go and no-go trials, as the monkey learned the discrimination task. The s-N, d-P potential in this gyrus may reflect an information processing prior to the discrimination in the prefrontal cortex.
Gemba
H
H
Department of Integrative Brain Science, Faculty of Medicine, Kyoto University, Japan.
D000161:Acoustic Stimulation; D000818:Animals; D004193:Discrimination Learning / Q000502:physiology*; D004567:Electrodes, Implanted; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006225:Hand / Q000502:physiology; D008251:Macaca; D009068:Movement / Q000502:physiology; D017397:Prefrontal Cortex / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*