title: Diffusion approximations for stochastic compartmental models.
abstract: A diffusion approximation is developed for one-compartment systems with nonlinear elimination rates. Both impulsive input and continuous infusion are considered. Explicit expressions for the mean and autocovariance functions of the contents of the compartment as time elapses are given.
authors.affiliation: Department of Mathematics, University of Queensland, Australia.
authors.forename: M J
authors.initials: MJ
authors.lastname: Faddy
mesh_terms: D006801:Humans; D008433:Mathematics; D008962:Models, Theoretical; D010599:Pharmacokinetics; D013269:Stochastic Processes