Characterization and regulation of pre-ovulatory secretion of gonadotrophin-releasing hormone.
Using an elegant method for sampling of pituitary portal blood the secretory characteristics of gonadotrophin-releasing hormone (GnRH) during the oestradiol induced surge are studied. It is demonstrated that the neuroendocrine signal for ovulation in the ewe is a surge of GnRH released into the portal blood.
Moenter
S M
SM
Reproductive Sciences Program, University of Michigan, Ann Arbor 48109-0404.
Caraty
A
A
Lehman
M N
MN
Karsch
F J
FJ
D000818:Animals; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D005498:Follicular Phase / Q000502:physiology; D007987:Gonadotropin-Releasing Hormone / Q000097:blood / Q000378:metabolism*; D009490:Neurosecretory Systems / Q000502:physiology; D010060:Ovulation / Q000187:drug effects / Q000502:physiology*; D011169:Portal Vein
D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol