title: Invasive pulmonary aspergillosis and nocardiosis in an immunocompromised host.
abstract: A case of invasive pulmonary aspergillosis and nocardiosis following high dose prolonged steroid therapy given for suspected rapidly progressive glomerulonephritis is reported. A favourable response was achieved with a combination of amphotericin B and cotrimoxazole. A high index of suspicion and aggressive investigations are necessary for confirmation of diagnosis and early institution of appropriate therapy.
authors.affiliation: Department of Nephrology and Internal Medicine, PGIMER, Chandigarh.
authors.forename: P P
authors.initials: PP
authors.lastname: Varma
authors.forename: S
authors.initials: S
authors.lastname: Chugh
authors.forename: K L
authors.initials: KL
authors.lastname: Gupta
authors.forename: V
authors.initials: V
authors.lastname: Sakhuja
authors.forename: K S
authors.initials: KS
authors.lastname: Chugh
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D005921:Glomerulonephritis / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects*; D008875:Middle Aged; D009617:Nocardia Infections / Q000150:complications* / Q000188:drug therapy; D011859:Radiography; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000666:Amphotericin B; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D008775:Methylprednisolone