title: Intracavernous papaverine for impotence in spinal cord injured patients.
abstract: The majority of the spinal cord injury patients in our centre are young healthy males aged between 20 and 40 years. Loss of erection and inability to have coitus and father children have been responsible for inadequate sociosexual rehabilitation. In 1985, under urologist supervision, intracavernosal papaverine injection treatment was started in 101 volunteers, 65 paraplegics and 36 tetraplegics. Satisfactory erection sufficient for coital penetration was possible in 98 patients. Three had prolonged erection lasting beyond 4 hours. Only one required irrigation of the corpus with saline to achieve detumscence. One patient developed cavernosal fibrosis necessitating discontinuing the injection. Administration was under medical supervision so that possible complications of priapism/systemic effects could be promptly managed.
authors.affiliation: Spinal Cord Injury Centre, Military Hospital, Kirkee, Pune, India.
authors.forename: V K
authors.initials: VK
authors.lastname: Kapoor
authors.forename: A S
authors.initials: AS
authors.lastname: Chahal
authors.forename: S P
authors.initials: SP
authors.lastname: Jyoti
authors.forename: Y J
authors.initials: YJ
authors.lastname: Mundkur
authors.forename: S V
authors.initials: SV
authors.lastname: Kotwal
authors.forename: V K
authors.initials: VK
authors.lastname: Mehta
mesh_terms: D000328:Adult; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage* / Q000627:therapeutic use; D010410:Penile Erection / Q000187:drug effects; D010413:Penis; D013119:Spinal Cord Injuries / Q000150:complications*
chemical_list: D010208:Papaverine