title: [Prognostic factors of hepatocellular carcinoma. Multifactorial analysis of 84 cases].
abstract: To identify prognostic factors taking in account recent advances in diagnosis and treatment, 24 clinical, biological, and morphological factors were evaluated by means of uni- and multivariate analysis in 84 patients with hepatocellular carcinoma diagnosed between 1984 and 1991. Okuda's grading (P < 0.01), creatininemia (P < 0.01), and treatment (P < 0.05) were independent prognostic factors. Des-gamma-carboxyprothrombin reached a significant level (P < 0.05) in a subgroup of 32 recent patients but its prognostic value needs to be confirmed. Further prospective randomized trials comparing surgical and non-surgical treatment should take these factors into account.
authors.affiliation: Service d'Hépato-Gastroentérologie, CHU Nord, Amiens.
authors.forename: A
authors.initials: A
authors.lastname: Razafimahaleo
authors.forename: P
authors.initials: P
authors.lastname: Burtin
authors.forename: J P
authors.initials: JP
authors.lastname: Joly
authors.forename: J L
authors.initials: JL
authors.lastname: Dupas
authors.forename: D
authors.initials: D
authors.lastname: Capron-Chivrac
authors.forename: J P
authors.initials: JP
authors.lastname: Capron
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000401:mortality* / Q000628:therapy; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000401:mortality* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D011516:Prothrombin / Q000032:analysis
chemical_list: D011516:Prothrombin; D003404:Creatinine
vernacular_title: Facteurs pronostiques du carcinome hépatocellulaire. Analyse multifactorielle de 84 cas.