title: [Endometrioid adenocarcinoma of the uterine isthmus associated with atypical endometrial hyperplasia and polycystic ovaries. Apropos of a case with bicornuate uterus in a 38 year old woman].
abstract: A 38 year old patient with multiple known risk factors for endometrial carcinoma (monophasic cycles, obesity, familial prediabetes, nulliparity, polycystic ovaries with diffuse thecal hyperplasia) presented with metrorrhagia caused by an endometrial lesion for which the diagnosis hesitated between atypical endometrial hyperplasia and carcinoma. Hysterectomy was performed because of the presence of a bicornuate uterus, obesity of 130 kg and the patient's lack of desire to have children. Examination of the uterus did not reveal any myometrial invasion in contact with the hyperplastic endometrium. The discovery of an endometrioid carcinomatous metastasis in the lower third of the vagina one year later allowed the retrospective detection of a 3 mm endometrioid carcinoma in the isthmus. No other metastases or recurrence were observed with a follow-up of 5 years.
authors.affiliation: Institut de Pathologie, Strasbourg.
authors.forename: A
authors.initials: A
authors.lastname: Chadli-Debbiche
authors.forename: P
authors.initials: P
authors.lastname: Dellenbach
authors.forename: E
authors.initials: E
authors.lastname: Philippe
authors.forename: M
authors.initials: M
authors.lastname: Hummel
mesh_terms: D000328:Adult; D018269:Carcinoma, Endometrioid / Q000150:complications / Q000473:pathology* / Q000556:secondary; D004714:Endometrial Hyperplasia / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000601:surgery; D014591:Uterine Diseases / Q000150:complications / Q000601:surgery; D014594:Uterine Neoplasms / Q000150:complications / Q000473:pathology*; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery; D014625:Vaginal Neoplasms / Q000473:pathology / Q000556:secondary
vernacular_title: Adénocarcinome endométrioïde de l'isthme utérin associé à une hyperplasie endométriale atypique et à des ovaires polykystiques. A propos d'un cas sur utérus didelphe chez une femme de 38 ans.