title: No major differences in energy metabolism between matched and unmatched groups of 'large-eating' and 'small-eating' men.
abstract: Rates of energy expenditure (J/kg fat-free mass (FFM) per min) in normal weight, 'small-eating' men were compared with those obtained for normal weight (n 8) and underweight (n 5) 'large-eating' men. For the matched groups of 'large-' and 'small-eaters' there were no differences in resting metabolic rate (RMR) measurements but during controlled daily activities there was a small but significant increase (P < 0.05) in energy expenditure in the 'large-eaters'. These results contrast with those obtained for the unmatched groups where energy requirements were about 10% (P < 0.01) higher in the underweight 'large-eaters' at rest but were not different during the more energetic (walking) activities. However, after adjustment for differences in FFM between these two groups, the resting energy expenditures of the 'large-eaters' (82.54 (SE 1.51) J/kg FFM per min) were similar to those of the 'small-eaters' (81.87 (SE 1.51) J/kg FFM per min). Oral temperatures were significantly higher in the matched (0.35-0.65 degrees) and unmatched (0.7-0.9 degrees) 'large-eaters' both at rest and during the different activities, but the thermic effect of food (50 kJ/kg FFM) was one fifth lower (not significant) in both groups of 'large-eaters'. These results provide little evidence for any major metabolic differences between groups of 'large-eating' and 'small-eating' men.
authors.affiliation: CSIRO, Division of Human Nutrition, Adelaide, Australia.
authors.forename: D
authors.initials: D
authors.lastname: Clark
authors.forename: F
authors.initials: F
authors.lastname: Tomas
authors.forename: R T
authors.initials: RT
authors.lastname: Withers
authors.forename: S D
authors.initials: SD
authors.lastname: Neville
authors.forename: S R
authors.initials: SR
authors.lastname: Nolan
authors.forename: M
authors.initials: M
authors.lastname: Brinkman
authors.forename: C
authors.initials: C
authors.lastname: Chandler
authors.forename: C
authors.initials: C
authors.lastname: Clark
authors.forename: F J
authors.initials: FJ
authors.lastname: Ballard
authors.forename: M
authors.initials: M
authors.lastname: Berry
mesh_terms: D000328:Adult; D001481:Basal Metabolism; D001833:Body Temperature Regulation; D001835:Body Weight; D002153:Calorimetry, Indirect; D004734:Energy Metabolism; D005247:Feeding Behavior / Q000502:physiology*; D006801:Humans; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D009584:Nitrogen / Q000652:urine; D010101:Oxygen Consumption; D005082:Physical Exertion; D011506:Proteins / Q000378:metabolism
chemical_list: D011506:Proteins; D009584:Nitrogen