The therapeutic action of cyclosporin A (Sandimmun): its application in rheumatoid arthritis.
The main properties, mechanism of action, mode of administration, side effects and therapeutic indications of Cyclosporin A are reviewed, with special emphasis on its applications in rheumatoid arthritis (RA). The drug administration in small doses, only in patients with severe RA, refractory to the usual antirheumatic therapy, was effective in a significant proportion of cases.
Suţeanu
S T
ST
Clinic of Internal Medicine, Dr. I. Cantacuzino Hospital, Bucharest.
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D000075202:Contraindications; D016572:Cyclosporine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007668:Kidney / Q000187:drug effects; D013997:Time Factors
D016572:Cyclosporine