title: [Prognostic factors in primary gastric non-Hodgkin's lymphoma--results of uni- and multivariate analysis].
abstract: Retrospectively analyzed data of 41 patients with primary gastric non-Hodgkin lymphoma which were all treated by gastric resection are presented with regard to their histopathologic and clinical findings. 87% of the patients were distributed on stage EI and EII (51% high-grade and 49% low-grade lymphoma). R0 resection was achieved in 80% of our cases and in 27% of the cases gastric resection was part of a multimodal therapy. The median follow up of the living patients was 42 months, the overall 5-year survival rate 74%. Tumor stage, extent of surgical resection, histologic grade, tumor site, R0-resection and tumor size showed a significant prognostic influence on survival. The question whether R0 resectable cases benefit from an adjuvant therapy must be answered by further randomized studies.
authors.affiliation: Chirurgische Klinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München.
authors.forename: G A
authors.initials: GA
authors.lastname: Melcher
authors.forename: J D
authors.initials: JD
authors.lastname: Roder
authors.forename: U
authors.initials: U
authors.lastname: Fink
authors.forename: A
authors.initials: A
authors.lastname: Funk
authors.forename: C
authors.initials: C
authors.lastname: Fellbaum
authors.forename: R
authors.initials: R
authors.lastname: Busch
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D016393:Lymphoma, B-Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000401:mortality*; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis; D015996:Survival Rate
vernacular_title: Prognosefaktoren beim primär gastrischen Non-Hodgkin Lymphom--Ergebnisse einer uni- und multivariaten Analyse.