title: The Loyola University lung transplant experience.
abstract: BACKGROUND
  We reviewed our experience with isolated lung transplantation at Loyola University Medical Center, Maywood, Ill. From April 1990 through June 1992, 33 lung transplantations for end-stage pulmonary disease were performed (30 single lung, three bilateral single lung). Recipient diagnoses include chronic obstructive pulmonary disease, alpha 1-antiprotease deficiency, pulmonary fibrosis, primary pulmonary hypertension, Eisenmenger's syndrome, sarcoidosis, cystic fibrosis, bronchiectasis, and bronchiolitis obliterans.
  
  
  METHODS
  For patients who underwent transplantation for end-stage obstructive airway disease, we retrospectively reviewed functional indexes before and after transplantation. In addition, the overall survival rate was determined.
  
  
  RESULTS
  Successful transplantation resulted in a marked improvement in functional capacity. Single-lung transplantation for end-stage obstructive airway disease resulted in a threefold improvement in the 1-second forced expiratory volume, from 0.49 to 1.64 L. The actual survival for all isolated lung transplant recipients (including both single-lung and bilateral single-lung procedures) was 73%, with a 15% 30-day mortality.
  
  
  CONCLUSIONS
  Isolated lung transplantation can significantly improve functional capacity as well as the quality of life in patients with end-stage lung disease.
authors.affiliation: Department of Medicine, Loyola University of Chicago, Stritch School of Medicine, Maywood, IL.
authors.forename: J R
authors.initials: JR
authors.lastname: Doud
authors.forename: M M
authors.initials: MM
authors.lastname: McCabe
authors.forename: A
authors.initials: A
authors.lastname: Montoya
authors.forename: E R
authors.initials: ER
authors.lastname: Garrity
mesh_terms: D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007087:Illinois; D008171:Lung Diseases / Q000601:surgery; D016040:Lung Transplantation / Q000009:adverse effects / Q000191:economics / Q000592:standards*; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis; D014019:Tissue Donors; D016896:Treatment Outcome