title: Prevalence of enteropathogenic and enterotoxigenic Escherichia coli in children with and without diarrhoea in Esteli, Nicaragua.
abstract: In Esteli, Las Segovias, Nicaragua, the frequency of isolations of enteropathogenic (EPEC), and enterotoxigenic E. coli (ETEC) was investigated in 100 children with (n = 50) and without diarrhoea (n = 50). EPEC was found to be significantly (p < 0.05) more frequent in diarrhoeal (16%) than in healthy children (4%). Detailed analyses revealed that 6 serotypes of E. coli were involved. Isolation of ETEC was not statistically significantly different (p > 0.05) in diarrhoeal (28%) and healthy children (16%). Determination of the susceptibility of isolated E. coli indicated a high level of resistance to common antimicrobial drugs. These resistant strains of E. coli might become a health problem in this part of Nicaragua.
authors.affiliation: University Children's Hospital, Heidelberg, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Mayatepek
authors.forename: E
authors.initials: E
authors.lastname: Seebass
authors.forename: V
authors.initials: V
authors.lastname: Hingst
authors.forename: A
authors.initials: A
authors.lastname: Kroeger
authors.forename: H G
authors.initials: HG
authors.lastname: Sonntag
mesh_terms: D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D005243:Feces / Q000382:microbiology*; D006801:Humans; D007223:Infant; D009527:Nicaragua / Q000453:epidemiology; D013045:Species Specificity