title: Microfibrillar collagen hemostat during laparoscopically directed liver biopsy.
abstract: Meticulous hemostasis is a necessity during laparoscopic procedures in maintaining a clear visual field and avoiding the need for an extended laparotomy to secure hemostasis. Methods of hemostasis available to laparoscopic surgeons include direct pressure, suture/clip ligation, conventional monopolar or argon-enhanced coagulation, and application of topical hemostatic agents. The effectiveness of topical hemostatic agents for open surgical procedures has been demonstrated; however, to date, laparoscopic utilization of topical hemostatic agents has been hampered by lack of compatible forms for laparoscopic instillation. Endo-Avitene is a 15 x 50 mm rolled sheet of microfibrillar collagen hemostat, available in an applicator capable of placement through standard laparoscopic trocar. The use of Endo-Avitene during laparoscopically-directed liver biopsies in a porcine model is reported. The effective hemostatic properties of microfibrillar collagen hemostat were reaffirmed and the clinical utility of Endo-Avitene for laparoscopic use is demonstrated.
authors.affiliation: Department of Urology, University of California, Davis, Sacramento 95817.
authors.forename: R K
authors.initials: RK
authors.lastname: Low
authors.forename: M E
authors.initials: ME
authors.lastname: Moran
authors.forename: J E
authors.initials: JE
authors.lastname: Goodnight
mesh_terms: D000818:Animals; D001706:Biopsy / Q000295:instrumentation* / Q000379:methods; D003094:Collagen / Q000008:administration & dosage*; D016558:Hemostasis, Endoscopic / Q000295:instrumentation* / Q000379:methods; D006490:Hemostatics / Q000008:administration & dosage*; D020706:Laparoscopes; D010535:Laparoscopy / Q000379:methods; D008099:Liver / Q000473:pathology*; D013552:Swine
chemical_list: D006490:Hemostatics; D003094:Collagen