title: Extraosseous multiple myeloma: imaging features.
abstract: Multiple myeloma is a disseminated malignant neoplasm usually derived from a single clone of plasma cells. Patients with myeloma have diverse signs such as anemia, hypercalcemia, uremia, pathologic fractures, and recurrent infections. Extraosseous manifestations are found in less than 5% of patients with multiple myeloma. They can arise in any tissue, and their presence has been associated with more aggressive disease. The purpose of this essay is to illustrate the imaging findings of extraosseous myeloma and heighten awareness of this unusual manifestation of multiple myeloma.
authors.affiliation: Department of Diagnostic Radiology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: L A
authors.initials: LA
authors.lastname: Moulopoulos
authors.forename: C A
authors.initials: CA
authors.lastname: Granfield
authors.forename: M A
authors.initials: MA
authors.lastname: Dimopoulos
authors.forename: E E
authors.initials: EE
authors.lastname: Kim
authors.forename: R
authors.initials: R
authors.lastname: Alexanian
authors.forename: H I
authors.initials: HI
authors.lastname: Libshitz
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging*; D012878:Skin Neoplasms / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014565:Urogenital Neoplasms / Q000000981:diagnostic imaging