Temporary redistribution of hepatic or pancreatic blood flow by vascular occluders during intra-arterial chemotherapy for carcinoma of the liver or pancreas.
Surgically placed inflatable vascular occluders temporarily increased or restricted the target volume for intra-arterial therapy for tumors in the liver and pancreas. Proximal occlusion of the common hepatic artery directed retrograde flow from the cannulated gastroduodenal artery into a variant left hepatic artery in one patient with carcinoma of the liver. Occlusion of the distal splenic artery and common hepatic artery after distal gastrectomy with cannulation of the left gastric artery gave selective perfusion of the tumor-bearing pancreatic head in three patients. The occlusions had no untoward effects and the regional infusions seemed to retard local tumor growth.
Shimamura
Y
Y
Chibanishi West Hospital, Matsudo, Japan.
Gunvén
P
P
Ishii
M
M
Abe
K
K
D002404:Catheterization / Q000379:methods; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods*; D008099:Liver / Q000098:blood supply*; D008113:Liver Neoplasms / Q000098:blood supply* / Q000188:drug therapy; D008297:Male; D010179:Pancreas / Q000098:blood supply*; D010190:Pancreatic Neoplasms / Q000098:blood supply* / Q000188:drug therapy