[New treatment of psoriasis with the vitamin D analogue calcipotriol].
A new topical treatment for psoriasis was introduced in 1992 when the vitamin D analogue calcipotriol was registered in Norway. This is a new therapeutic principle for psoriasis. Calcipotriol induces differentiation and inhibits proliferation of the keratinocytes. Application twice daily for 6-8 weeks gives a 60-70% improvement in plaque type psoriasis. No serious side effects have been reported when using up to 100 grams of the ointment weekly.
Austad
J
J
Rikshospitalet, Oslo.
D000287:Administration, Topical; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000737:chemistry; D003879:Dermatologic Agents / Q000008:administration & dosage*; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology
D003879:Dermatologic Agents; C055085:calcipotriene; D002117:Calcitriol
Ny behandling av psoriasis med D-vitaminanalogen calcipotriol.