Escherichia coli serotype K45 capsular antigen: a glycan containing 3-acetamido-3,6-dideoxygalactopyranose.
The primary structure of the acidic capsular antigen of Escherichia coli O8:K45:H9 was shown by glycose analysis, methylation analysis, and one- and two-dimensional 1H and 13C NMR spectroscopy to be composed of repeating branched tetrasaccharide units having the structure: [formula: see text] The polysaccharide contains the uncommon amino sugar 3-acetamido-3,6-dideoxy-D- galactopyranose, which has not been previously identified in a capsular antigen.
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School of Pharmaceutical Sciences, Rhodes University, Grahamstown, South Africa.
Parolis
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Parolis
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LA
D000116:Acetylgalactosamine / Q000032:analysis; D000117:Acetylglucosamine / Q000032:analysis; D000942:Antigens, Bacterial / Q000737:chemistry* / Q000302:isolation & purification; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D004926:Escherichia coli / Q000737:chemistry* / Q000145:classification; D005643:Fucose / Q000032:analysis; D005690:Galactose / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000737:chemistry* / Q000302:isolation & purification; D011135:Polysaccharides, Bacterial / Q000737:chemistry* / Q000302:isolation & purification
D000942:Antigens, Bacterial; D009844:Oligosaccharides; D011135:Polysaccharides, Bacterial; D005643:Fucose; D000116:Acetylgalactosamine; D000117:Acetylglucosamine; D005690:Galactose