title: Dermatoglyphics in type 1 diabetes mellitus.
abstract: Although fingerprints and handprints are widely used in criminology, it is only recently that this approach has been applied to the field of medical and genetic diagnoses. In order to investigate dermatoglyphics in Type 1 diabetes mellitus, quantitative characteristics of fingers and palms (ridge count and main line indices) as well as qualitative parameters such as digital and interdigital patterns, the position of the palmar axial triradii and main line courses were analysed in 88 male and 108 female Type 1 diabetic patients and compared with data from 100 male and 99 female normal controls. Type 1 diabetic patients show a lower third finger ridge count (p < 0.05) and a-b ridge count (p < 0.001) and higher transversality of the main lines as indicated by the main line index value (p < 0.001) or the ending of the main line A in a specific sector 5, 5', and 5" (p < 0.001) compared with controls. In addition, diabetic patients show higher frequency of palmar axial t' and t" triradii (p < 0.001) and a lower frequency of 'true' patterns in the fourth interdigital and thenar area (p < 0.001) than controls. By multivariate analysis of quantitative and qualitative variables a predictive value of 78.6% and 77.3%, respectively, for male, and 81.4% and 82.2%, respectively, for female Type 1 diabetic patients was found. In conclusion, dermatoglyphics seem to be an interesting tool for genetic studies related to Type 1 diabetes.
authors.affiliation: Diabetes Research Institute, Munich, Germany.
authors.forename: A G
authors.initials: AG
authors.lastname: Ziegler
authors.forename: R
authors.initials: R
authors.lastname: Mathies
authors.forename: G
authors.initials: G
authors.lastname: Ziegelmayer
authors.forename: H J
authors.initials: HJ
authors.lastname: Baumgartl
authors.forename: A
authors.initials: A
authors.lastname: Rodewald
authors.forename: V
authors.initials: V
authors.lastname: Chopra
authors.forename: E
authors.initials: E
authors.lastname: Standl
mesh_terms: D003878:Dermatoglyphics; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D012727:Sex Characteristics; D012737:Sex Factors