[A case of giant hepatocellular carcinoma effectively treated by UFT].
An 84-year-old woman who suffered from heart failure was admitted to our hospital in July 1991. We found a hepatocellular carcinoma, of about 9 cm in diameter in her right liver lobe. The patient could not be operated on, TAE and PEIT, so she has been administered UFT (300 mg/day) orally every day. After seven months, observing the patient by means of computerized tomography, we noticed that the tumor had decreased in size until only a small cyst was left. PIVKA-II reached the normal range (under 0.063 AU/ml) from its previous level (42.940 AU/ml). She has maintained a good state of health for about two years now. This is considered a very rare case in which chemotherapy proved to be completely effective, and the patient has survived for a long time afterwards.
Urabe
T
T
Dept. of Internal Medicine, Hiroshima Prefectural Setoda Hospital.
Hino
F
F
D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015415:Biomarkers; D014408:Biomarkers, Tumor / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000188:drug therapy*; D011498:Protein Precursors / Q000378:metabolism; D011516:Prothrombin / Q000378:metabolism; D012074:Remission Induction; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
D015415:Biomarkers; D014408:Biomarkers, Tumor; D011498:Protein Precursors; D005641:Tegafur; C008208:acarboxyprothrombin; D014498:Uracil; D011516:Prothrombin