title: [Analgesic effect and gastro-intestinal motility inhibitory action of 3-hydroxy-4-methoxy-acetophenone from Cynanchum paniculatum (Bunge) Kitagawa].
abstract: 3-Hydroxy-4-methoxy-acetophenone (HMA) isolated from Cynanchum paniculatum was found to have analgesic effect and inhibitory action on the gastro-intestinal motility. The effect and action were equivalent to that of paeonol, HMA displayed a very low degree of antibacterial activity against Escherichia coli and Shigella flexneri.
authors.affiliation: Nanjing Institute of Materia Medica.
authors.forename: F Z
authors.initials: FZ
authors.lastname: Sun
authors.forename: M
authors.initials: M
authors.lastname: Cai
authors.forename: F C
authors.initials: FC
authors.lastname: Lou
mesh_terms: D000098:Acetophenones / Q000302:isolation & purification / Q000494:pharmacology*; D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects*; D008297:Male; D051379:Mice; D017288:Pain Threshold / Q000187:drug effects*; D012763:Shigella flexneri / Q000187:drug effects
chemical_list: D000098:Acetophenones; D000700:Analgesics; D004365:Drugs, Chinese Herbal; C085119:3-hydroxy-4-methoxyacetophenone; C013638:paeonol