title: [Empty sella syndrome].
abstract: An empty sella is defined as a sella which, regardless of its size, is completely or partly filled with cerebrospinal fluid (CSF). Empty sella is occasionally found as a normal anatomical variation, which is referred to as primary empty sella. On the other hand, empty sella is also seen after surgery, irradiation or medical treatment of pituitary adenoma, which is called secondary empty sella. Magnetic resonance imaging (MRI) is useful in diagnosing empty sella. Primary empty sella is usually free from clinical symptoms but sometimes associated with headache, obesity, visual disturbance, non-traumatic CSF rhinorrhea and pituitary insufficiency. These associated findings constitute the empty sella syndrome. CSF rhinorrhea, visual disturbance and severe increased intracranial pressure are the indications for surgical treatment. Non-symptomatic cases require no treatment but periodical follow up is necessary.
authors.affiliation: Department of Neurosurgery, Shimane Medical University.
authors.forename: Y
authors.initials: Y
authors.lastname: Akiyama
authors.forename: T
authors.initials: T
authors.lastname: Yamasaki
authors.forename: T
authors.initials: T
authors.lastname: Kagawa
authors.forename: K
authors.initials: K
authors.lastname: Moritake
mesh_terms: D000236:Adenoma / Q000601:surgery; D000328:Adult; D004621:Embolization, Therapeutic; D004652:Empty Sella Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D006801:Humans; D010901:Pituitary Function Tests; D010911:Pituitary Neoplasms / Q000601:surgery; D011379:Prognosis