title: Local calcium regulatory compartments in neurons.
abstract: We have demonstrated that calcium concentration is under local control in two different systems: hippocampal pyramidal cell dendritic spines, and developing grasshopper pioneer neuron axons. Controllable, photoinduced damage to fura-2 filled processes was used for generating defined, reliable cytoplasmic calcium transients to demonstrate these local calcium regulatory compartments.
authors.affiliation: Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523.
authors.forename: P B
authors.initials: PB
authors.lastname: Guthrie
authors.forename: R W
authors.initials: RW
authors.lastname: Davenport
authors.forename: S B
authors.initials: SB
authors.lastname: Kater
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000502:physiology*; D003712:Dendrites / Q000502:physiology / Q000648:ultrastructure; D005456:Fluorescent Dyes; D006110:Grasshoppers / Q000502:physiology*; D006624:Hippocampus / Q000166:cytology / Q000502:physiology; D006706:Homeostasis / Q000502:physiology; D066298:In Vitro Techniques; D009474:Neurons / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D015398:Signal Transduction / Q000502:physiology
chemical_list: D005456:Fluorescent Dyes; D002118:Calcium