title: Multiple Beau's lines in a patient with fever of unknown origin.
abstract: We describe a case of fever of unknown origin (FUO) of 9 months' duration in which the finding of regularly spaced multiple Beau's lines (the "ladder nail" sign) pointed to the possibility of a relapsing fever of the Pel-Ebstein variety and an underlying lymphoma. Subsequent investigation confirmed the association of the Beau's lines and fever, as well as the diagnosis of Hodgkin's disease as the cause of the FUO. In this setting, Beau's lines may provide an important diagnostic clue and should be carefully looked for on physical examination.
authors.affiliation: Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614-0622.
authors.forename: K L
authors.initials: KL
authors.lastname: Colvett
authors.forename: D
authors.initials: D
authors.lastname: Patel
authors.forename: J K
authors.initials: JK
authors.lastname: Smith
mesh_terms: D005335:Fever of Unknown Origin / Q000209:etiology*; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000209:etiology*; D010808:Physical Examination