Side effects of phenytoin related to the xenobiotics metabolism by cytochrome P-450-linked monooxygenase of liver microsomes in dark Agouti rats.
Taki
K
K
Department of Neuropsychiatry, Kagawa Medical School.
Iwahashi
K
K
Kugoh
T
T
Matsuo
Y
Y
Ichikawa
Y
Y
Hosokawa
K
K
Suwaki
H
H
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000502:physiology*; D005260:Female; D008658:Inactivation, Metabolic / Q000502:physiology; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D009410:Nerve Degeneration / Q000187:drug effects; D010105:Oxygenases / Q000502:physiology*; D010672:Phenytoin / Q000493:pharmacokinetics / Q000633:toxicity*; D011689:Purkinje Cells / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors
D010672:Phenytoin; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases