title: [Detection of secretory acid proteinase enzyme from Candida strains on protein supplemented agar media].
abstract: In this study, we identified the species of 130 candida strains isolated from various clinical specimens, and we also investigated the secretory acid proteinase activity of these strains on hemoglobin, albumin and casein containing agar media. In 65 of 75 C. albicans, 8 of 15 C. tropicalis, 5 of 15 C. pseudotropicalis, in 3 C. stellatoidea and in 2 C. glabrata strains enzyme activity was shown. We couldn't detect proteinase activity in any of the 7 C. krusei, 7 C. parapsilosis and in 6 C. guilliermondii strains. Enzyme activity was shown to be inhibited when proteolytic strains were treated with specific inhibitor pepstatin-A.
authors.affiliation: Mikrobiyoloji Uzmani, Hacettepe Universitesi, Tip Fakültesi Mikrobiyoloji Anabilim Dali.
authors.forename: N
authors.initials: N
authors.lastname: Cerikcioğlu
authors.forename: R
authors.initials: R
authors.lastname: Alaçam
mesh_terms: D000418:Albumins / Q000378:metabolism*; D016282:Aspartic Acid Endopeptidases / Q000032:analysis*; D002175:Candida / Q000187:drug effects / Q000201:enzymology*; D002364:Caseins / Q000378:metabolism*; D003470:Culture Media; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D010436:Pepstatins / Q000494:pharmacology
chemical_list: D000418:Albumins; D002364:Caseins; D003470:Culture Media; D006454:Hemoglobins; D010436:Pepstatins; C014195:Streptomyces pepsin inhibitor; D016282:Aspartic Acid Endopeptidases; C031375:pepstatin
vernacular_title: Kandida suşlarinda salgisal asit proteinaz enzim varliğinin proteinli agar besiyerlerinde gösterilmesi.