title: Third cranial nerve palsy caused by gummatous neurosyphilis: MR findings.
abstract: The clinical and MR findings in an unusual case of gummatous neurosyphilis are reported. A 44-year-old woman suffering from diplopia and right-sided headaches was admitted. Physical examination and routine laboratory parameters were normal except for a third-nerve palsy. MR images revealed a contrast-enhancing lesion of the upper brain stem and third cranial nerve. Differential diagnosis included neuroma of the third cranial nerve, as well as neurosarcoidosis and other inflammatory processes. Serologic tests and lumbar puncture revealed the presence of active syphilis. After intravenous treatment with penicillin G, follow-up MR examinations showed diminishing size of the lesion with its complete resolution within 3 months.
authors.affiliation: Department of Radiology, University of Munich, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Vogl
authors.forename: S
authors.initials: S
authors.lastname: Dresel
authors.forename: H
authors.initials: H
authors.lastname: Lochmüller
authors.forename: C
authors.initials: C
authors.lastname: Bergman
authors.forename: C
authors.initials: C
authors.lastname: Reimers
authors.forename: J
authors.initials: J
authors.lastname: Lissner
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009494:Neurosyphilis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis / Q000209:etiology*