[Photobiological processes in biomembranes under the effect of ultraviolet radiation on animal cells, tissues, and organs].
The current knowledge about the mechanisms of the lipid photoperoxidation (LPPO) and the role of the process in the effects of the UV-irradiation of cells and tissues is reviewed. The LPPO in biomembranes occurs as a result of the lipid hydroperoxide phototransformation to free radicals and the antioxidant photolysis. The LPPO significantly depends on the structural state of biomembranes. The UV-radiation stimulates the two types of dark lipid peroxidation (LPO): the free radical non-enzymatic peroxidation, and the cyclooxygenase peroxidation. The UV-radiation produces increase of the membrane ion permeability, decrease (or enhancement) of the aggregatory interaction of cells, and changes of the membrane enzymatic activity. The LPPO and the dark non-enzymatic LPO play an important role in the changes of the membrane functions under the UV-irradiation. The dark non-enzymatic LPO is important for the development of UV erythema. The cyclooxygenase LPO may be responsible for the curative properties of the UV-irradiated blood.
Roshchupkin
D I
DI
Murina
M A
MA
D000818:Animals; D001769:Blood / Q000528:radiation effects*; D001803:Blood Transfusion; D002462:Cell Membrane / Q000528:radiation effects; D015227:Lipid Peroxidation / Q000528:radiation effects*; D010084:Oxidation-Reduction; D012867:Skin / Q000528:radiation effects*; D014466:Ultraviolet Rays
Fotobiologicheskie protsessy v biomembranakh pri deĭstvii ul'trafioletovogo izlucheniia na kletki, tkani i organy zhivotnykh.