Fungitoxicity of essential oils against dermatophytes.
Sixteen essential oils were screened in vitro for their fungitoxicity against the two dermatophytes Trichophyton rubrum and Microsporum gypseum. Five oils (from Artemisia nelagrica, Caesulia axillaris, Chenopodium ambrosioides, Cymbopogon citratus and Mentha arvensis) showed strong activity and were assessed for their fungitoxicity against eight other dermatophytes as well as against Aspergillus fumigatus and Cladosporium trichoides. These five essential oils by formulation of ointments were able to cure experimental ringworm in guinea pigs within 7 to 12 days. Artemisia oil was found to be the most effective essential oil.
Kishore
N
N
Department of Botany, Banaras Hindu University, Varanasi, India.
Mishra
A K
AK
Chansouria
J P
JP
D000818:Animals; D003883:Arthrodermataceae / Q000187:drug effects*; D006168:Guinea Pigs; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects; D003904:Mitosporic Fungi / Q000187:drug effects; D009822:Oils, Volatile / Q000494:pharmacology*; D010938:Plant Oils / Q000494:pharmacology*; D010944:Plants / Q000737:chemistry; D014005:Tinea / Q000188:drug therapy*; D014249:Trichophyton / Q000187:drug effects
D009822:Oils, Volatile; D010938:Plant Oils