title: Post-traumatic seizures.
abstract: Acute traumatic brain injury causes a cascade of changes in brain metabolism, blood flow, and homeostasis that are challenges to survival. Seizures, whether focal or convulsive, may be a manifestation of the acute injury response and are liable to complicate management. This article discusses mechanisms and biochemical effects of brain injury, cellular mechanisms of epileptogenesis, genetic factors, prevention and prophylaxis, alteration of brain injury responses, and recommendations for management.
authors.affiliation: Department of Neurology, University of Texas Health Science Center, Houston.
authors.forename: L J
authors.initials: LJ
authors.lastname: Willmore
mesh_terms: D001930:Brain Injuries / Q000150:complications* / Q000503:physiopathology; D004834:Epilepsy, Post-Traumatic / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D012640:Seizures / Q000209:etiology* / Q000517:prevention & control