Relation between intra-articular temperature of the arthritic temporomandibular joint and presence of calcitonin gene-related peptide in the joint fluid. A clinical study.
Arthritic temporomandibular joints were investigated for intra-articular temperature and joint fluid content of calcitonin gene-related peptide. Eleven patients (16 joints) with rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, or chronic unspecific polyarthritis or monarthritis participated in the study. The intra-articular temperature varied between 35.5 and 37.5 degrees C, with a mean of 36.5 degrees C. The concentration of calcitonin gene-related peptide varied between 7.5 and 749.0 pmol/l, with a mean of 108.6 pmol/l. There was a positive correlation between the intra-articular temperature and the joint fluid concentration of calcitonin gene-related peptide. The plasma level of the peptide was on an average 5% of the joint fluid level.
Appelgren
A
A
Department of Clinical Oral Physiology, Karolinska Institutet, Huddinge, Sweden.
Appelgren
B
B
Kopp
S
S
Lundeberg
T
T
Theodorsson
E
E
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000378:metabolism / Q000503:physiopathology*; D001831:Body Temperature; D015740:Calcitonin Gene-Related Peptide / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013582:Synovial Fluid / Q000378:metabolism*; D013704:Temporomandibular Joint / Q000378:metabolism / Q000503:physiopathology*
D015740:Calcitonin Gene-Related Peptide