title: The callosal-septal interface lesion in multiple sclerosis: effect of sequence and imaging plane.
abstract: We examined the effect of imaging plane and sequence on the demonstration of lesions at the callosal-septal interface (CSI) by magnetic resonance imaging in 20 patients with known multiple sclerosis. Variable-echo-(VE) T2- and proton density (PD) weighted images were performed in coronal axial and sagittal planes. Sagittal gradient echo (GE) T2- and PD-weighted images were also performed. Lesions at the CSI were seen in all patients and were all demonstrated on both sagittal and coronal VE images. Sagittal PD-weighted GE images were slightly less sensitive but showed good overall agreement with sagittal VE. Axial VE and sagittal T2-weighted GE images demonstrated CSI lesions poorly.
authors.affiliation: Department of Neuroradiology, Manchester Royal Infirmary, UK.
authors.forename: A
authors.initials: A
authors.lastname: Jackson
authors.forename: J B
authors.initials: JB
authors.lastname: Fitzgerald
authors.forename: J E
authors.initials: JE
authors.lastname: Gillespie
mesh_terms: D000328:Adult; D003337:Corpus Callosum / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000453:epidemiology; D015588:Observer Variation; D012680:Sensitivity and Specificity; D012688:Septum Pellucidum / Q000473:pathology