title: Characterization and regulation of pre-ovulatory secretion of gonadotrophin-releasing hormone.
abstract: Using an elegant method for sampling of pituitary portal blood the secretory characteristics of gonadotrophin-releasing hormone (GnRH) during the oestradiol induced surge are studied. It is demonstrated that the neuroendocrine signal for ovulation in the ewe is a surge of GnRH released into the portal blood.
authors.affiliation: Reproductive Sciences Program, University of Michigan, Ann Arbor 48109-0404.
authors.forename: S M
authors.initials: SM
authors.lastname: Moenter
authors.forename: A
authors.initials: A
authors.lastname: Caraty
authors.forename: M N
authors.initials: MN
authors.lastname: Lehman
authors.forename: F J
authors.initials: FJ
authors.lastname: Karsch
mesh_terms: D000818:Animals; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D005498:Follicular Phase / Q000502:physiology; D007987:Gonadotropin-Releasing Hormone / Q000097:blood / Q000378:metabolism*; D009490:Neurosecretory Systems / Q000502:physiology; D010060:Ovulation / Q000187:drug effects / Q000502:physiology*; D011169:Portal Vein
chemical_list: D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol