title: Clinical and biological prediction of axillary and internal mammary lymph node metastases in breast cancer.
abstract: We assessed the relationships among histological axillary (AX) or internal mammary (IM) metastases and clinical and biological variables, and then attempted to evaluate their predictive values for AX and IM metastases in 128 patients with invasive breast cancer. As the results, these clinical and biological variables were significantly correlated with AX and IM metastases. However, a metastatic index calculated from clinical and biological variables was not much better in prediction of the AX metastases than axillary nodal status, whereas it was useful to predict the IM metastases. Thus, the predictive ability was still limited. Since accurate prediction of AX and IM metastases is critical to therapeutic choice, however, further study would be required.
authors.affiliation: Operation Center, Kanazawa University Hospital, School of Medicine, Kanazawa University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Noguchi
authors.forename: N
authors.initials: N
authors.lastname: Ohta
authors.forename: M
authors.initials: M
authors.lastname: Thomas
authors.forename: H
authors.initials: H
authors.lastname: Kitagawa
authors.forename: M
authors.initials: M
authors.lastname: Earashi
authors.forename: I
authors.initials: I
authors.lastname: Miyazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Mizukami
mesh_terms: D000328:Adult; D000368:Aged; D001365:Axilla; D014408:Biomarkers, Tumor / Q000032:analysis*; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008323:Mammary Arteries; D008875:Middle Aged; D009697:Nucleolus Organizer Region / Q000737:chemistry; D015513:Oncogene Proteins / Q000032:analysis; D011003:Ploidies; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016019:Survival Analysis
chemical_list: D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D015513:Oncogene Proteins