Malignant histiocytosis in a cat.
A 13-year-old male domestic shorthair cat was found to have normocytic hypochromic regenerative anemia, lymphopenia, eosinopenia, thrombocytopenia, hyperglycemia, hyperbilirubinemia, and a prolonged activated partial thromboplastin time. Transfusions of packed RBC failed to maintain the PCV above 13% for > 8 hours. The cat was euthanatized. At necropsy, the spleen liver, lymph nodes, and bone marrow were infiltrated with malignant histiocytes undergoing erythrophagocytosis.
Court
E A
EA
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853-6401.
Earnest-Koons
K A
KA
Barr
S C
SC
Gould
W J
WJ
D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D054747:Histiocytic Sarcoma / Q000473:pathology / Q000662:veterinary*; D008099:Liver / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D013154:Spleen / Q000473:pathology