title: Purification and characterization of inhibitors of blood coagulation factor Xa from hematophagous organisms.
authors.affiliation: Department of Cardiovascular Biology, Rhone-Poulenc Rorer, Collegeville, Pennsylvania 19426.
authors.forename: C T
authors.initials: CT
authors.lastname: Dunwiddie
authors.forename: L
authors.initials: L
authors.lastname: Waxman
authors.forename: G P
authors.initials: GP
authors.lastname: Vlasuk
authors.forename: P A
authors.initials: PA
authors.lastname: Friedman
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000925:Anticoagulants / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D001777:Blood Coagulation; D002846:Chromatography, Affinity / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004285:Dogs; D015951:Factor Xa / Q000032:analysis; D065427:Factor Xa Inhibitors; D006801:Humans; D007202:Indicators and Reagents; D007447:Invertebrate Hormones / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D007700:Kinetics; D007865:Leeches; D008253:Macaca mulatta; D008969:Molecular Sequence Data; D009036:Moths; D011487:Protein Conformation; D011817:Rabbits; D011994:Recombinant Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D012469:Salivary Glands / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D013053:Spectrophotometry / Q000379:methods; D013917:Thrombin / Q000032:analysis / Q000378:metabolism; D013925:Thromboplastin / Q000032:analysis; D014162:Transfection / Q000379:methods
chemical_list: D000925:Anticoagulants; D065427:Factor Xa Inhibitors; D007202:Indicators and Reagents; D007447:Invertebrate Hormones; D011994:Recombinant Proteins; C053155:antistasin; D013925:Thromboplastin; D013917:Thrombin; D015951:Factor Xa