Hepatic infarction in a pregnant patient with the 'primary' antiphospholipid syndrome.
We describe a patient with previous venous thrombosis while using oral contraceptives and recurrent pregnancy loss, who presented with massive hepatic infarction in the last trimester of the fourth gestation. Thrombocytopenia, the lupus anticoagulant (LA) and the anticardiolipin antibody (aCL) were detected and a diagnosis of a 'primary' antiphospholipid syndrome (APS) was made. The clinical and histological manifestations and the differential diagnosis, especially with DIC and pre-eclampsia, are discussed.
Millán-Mon
A
A
Department of Internal Medicine, N Sra de La Candelaria Hospital, Santa Cruz de Tenerife, La Coruña Spain.
Porto
J L
JL
Novo
C
C
García-Martin
C
C
Guitián
D
D
D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000032:analysis; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D003276:Contraceptives, Oral / Q000009:adverse effects; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis; D005260:Female; D006801:Humans; D007238:Infarction / Q000209:etiology* / Q000276:immunology; D008099:Liver / Q000098:blood supply*; D016682:Lupus Coagulation Inhibitor / Q000032:analysis; D011225:Pre-Eclampsia / Q000175:diagnosis; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology* / Q000276:immunology; D013921:Thrombocytopenia / Q000175:diagnosis / Q000209:etiology; D013924:Thrombophlebitis / Q000209:etiology
D017153:Antibodies, Anticardiolipin; D003276:Contraceptives, Oral; D016682:Lupus Coagulation Inhibitor