title: Bazex's syndrome (acrokeratosis paraneoplastica)--first case report of association with a bladder carcinoma.
abstract: Bazex's acrokeratosis paraneoplastica is a clinically well-defined entity consisting of a distal erythemato-squamous eruption and nail dystrophy. It is always associated with neoplasia, mainly squamous carcinomas of the upper digestive and respiratory tracts; therefore, Bazek's acrokeratosis is considered to be a specific marker of internal malignancy. Two new cases of this syndrome are reported. The first was in a 41-year-old man with a squamous cell carcinoma of the oesophagus, the second in a 73-year-old man who presented with a transitional cell bladder carcinoma, an association not previously reported.
authors.affiliation: Department of Dermatology, Cruces Hospital, Bilbao, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Arregui
authors.forename: J A
authors.initials: JA
authors.lastname: Ratón
authors.forename: N
authors.initials: N
authors.lastname: Landa
authors.forename: R
authors.initials: R
authors.lastname: Izu
authors.forename: X
authors.initials: X
authors.lastname: Eizaquirre
authors.forename: J L
authors.initials: JL
authors.lastname: Díaz-Pérez
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications; D002295:Carcinoma, Transitional Cell / Q000150:complications*; D004938:Esophageal Neoplasms / Q000150:complications; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000150:complications* / Q000473:pathology; D009369:Neoplasms / Q000150:complications; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000150:complications*