title: [Infectious complications in oncologic-gynecologic surgery: clinical and economic evaluation].
abstract: In the Department of Obstetric and Gynecology, Faculty of Medicine-Varese, between March 1991 and June 1992, 74 consecutive patients undergoing elective oncologic surgery were evaluated in order to rationalize the use of antibiotics to decrease the costs of infectious complications. We divided the patients into two groups: a high infection risk group (in which every patient was submitted to antibiotic prophylaxis) and a low infection risk group (in which we didn't use any antibiotic prophylaxis). Our findings indicate that selection criteria for HIR patients are probably correct and in this group AP is necessary. In the LIR group, 45.5% of patients was not submitted to any antibiotic therapy. It's necessary to test the real efficacy of an AP in LIR patients in whom we had not a important incidence of infectious complications. In the LIR group AP should not exceed Lit. 23,251 per patient to be cost-effective.
authors.affiliation: Clinica Ostetrico-Ginecologica, Ospedale di Circolo e Fondazione Macchi, Varese.
authors.forename: P
authors.initials: P
authors.lastname: Beretta
authors.forename: M
authors.initials: M
authors.lastname: Franchi
authors.forename: F
authors.initials: F
authors.lastname: Zanaboni
authors.forename: S
authors.initials: S
authors.lastname: Confalonieri
authors.forename: S
authors.initials: S
authors.lastname: Salvatore
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001424:Bacterial Infections / Q000453:epidemiology*; D003362:Cost-Benefit Analysis; D005260:Female; D005833:Genital Neoplasms, Female / Q000191:economics / Q000601:surgery*; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects / Q000191:economics; D007558:Italy / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D011300:Preoperative Care; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Morbosità infettiva in chirurgia oncologico-ginecologica: valutazione clinica ed economica.