Probing the mechanism of TNF-alpha(cachectin)- and TNF-beta(lymphotoxin)-induced pancreatic inflammation with transgenic mice.
Ruddle
N H
NH
Yale University School of Medicine, New Haven, CT.
Picarella
D
D
Kratz
A
A
Li
C B
CB
Flavell
R A
RA
D000818:Animals; D005786:Gene Expression Regulation; D005813:Genes, Synthetic; D007249:Inflammation; D007328:Insulin / Q000097:blood; D007515:Islets of Langerhans / Q000378:metabolism / Q000473:pathology*; D007668:Kidney / Q000378:metabolism / Q000473:pathology; D008233:Lymphotoxin-alpha / Q000235:genetics / Q000633:toxicity*; D051379:Mice; D008810:Mice, Inbred C57BL; D016688:Mice, Inbred NOD; D008822:Mice, Transgenic; D009928:Organ Specificity; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis / Q000633:toxicity; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics / Q000633:toxicity*
D007328:Insulin; D008233:Lymphotoxin-alpha; D011993:Recombinant Fusion Proteins; D014409:Tumor Necrosis Factor-alpha