A subgroup of bipolar cells in human retina is GABA-immunoreactive.
The distribution of GABA in the perifoveal and the near and far peripheral region of human retina was studied with peroxidase anti-peroxidase immunocytochemistry applied on semithin epoxy resin sections. Among the labeled amacrine cells in these regions, four types can be identified: putative diffuse A2 amacrines, stratified semilunar amacrines, interstitial amacrines and small displaced amacrines. GABA-immunoreactive interplexiform cells and ganglion cells also occur. Contrary to previous post-embedding studies, our preparations show that some bipolar cells in the near and far peripheral region are GABA-immunopositive. This indicates that a number of bipolar cells in human retina does have an enhanced GABA content.
Van Haesendonck
E
E
Eye Research Laboratory, Katholieke Universiteit Leuven, U.Z. Sint-Rafaël, Belgium.
Missotten
L
L
D015353:Eye Enucleation; D006801:Humans; D007150:Immunohistochemistry; D016613:Plastic Embedding; D012160:Retina / Q000166:cytology / Q000378:metabolism*; D012165:Retinal Ganglion Cells / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000276:immunology / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid