[The effect of the electrical stimulation of the superior colliculli on focal epileptic activity in the cerebral cortex ].
Acute experiments in rats showed that SC electrical stimulation (ES) (100 Hz, 5 V, 0.25 ms) resulted in suppression of the epileptic activity in contralateral strychnine-induced (0.1%; 1.0%) focus and shortening of the focus existence time. After electrocoagulation of SC ES-zone the EpA in the focus was restored. ES of SC ipsilateral to strychnine-induced (0.1%) focus caused an increase in the spike frequencies but significant part of the antiepileptic system.
Kryzhanovskiĭ
G N
GN
Shandra
A A
AA
Godlevskiĭ
L S
LS
Vikhrestiuk
S L
SL
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002540:Cerebral Cortex / Q000503:physiopathology*; D004558:Electric Stimulation / Q000295:instrumentation / Q000379:methods; D004569:Electroencephalography / Q000295:instrumentation / Q000379:methods; D004828:Epilepsies, Partial / Q000139:chemically induced / Q000503:physiopathology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013331:Strychnine; D013477:Superior Colliculi / Q000502:physiology*; D013997:Time Factors
D013331:Strychnine
Vliianie élektricheskoĭ stimuliatsii verkhnikh bugorkov chetverokholmiia na ochagovuiu épilepticheskuiu aktivnost' v kore golovnogo mozga.