Acute obstructive respiratory diseases (ARD) and bacterial complications of ARD (pneumonia, sinusitis) in infants and children associated with human herpesvirus-6 infection.
The existence of catharreal respiratory symptoms (such as pharyngitis, tracheitis, bronchitis etc.) is established as the usual manifestation of "exanthema subitum" due to acute human herpesvirus-6 (HHV-6) infection. But so far pneumonia, purulent sinusitis, purulent otitis media and/or acute obstructive bronchitis (bronchiolitis) in infants and children have not been described. Here we report the results of observations of 2 children with bronchopneumonia/sinusitis maxillaris and severe bronchiolitis associated with an acute HHV-6 infection. Other respiratory viruses were excluded as agents causing the ARD.
Wiersbitzky
S
S
Department of Pediatrics, Ernst-Moritz-Arndt-University, Greifswald, Germany.
Bruns
R
R
Wiersbitzky
H
H
Ballke
E H
EH
D000914:Antibodies, Viral / Q000032:analysis; D001424:Bacterial Infections / Q000276:immunology / Q000382:microbiology; D001988:Bronchiolitis / Q000276:immunology / Q000382:microbiology*; D001991:Bronchitis / Q000276:immunology / Q000382:microbiology*; D001996:Bronchopneumonia / Q000276:immunology / Q000382:microbiology*; D005077:Exanthema Subitum / Q000276:immunology / Q000382:microbiology; D005260:Female; D006566:Herpesviridae Infections / Q000276:immunology / Q000382:microbiology*; D015654:Herpesvirus 6, Human / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D007223:Infant; D008297:Male; D015523:Maxillary Sinusitis / Q000276:immunology / Q000382:microbiology*; D015163:Superinfection / Q000276:immunology / Q000382:microbiology; D014774:Virulence
D000914:Antibodies, Viral