[Clinical evaluation of Clozapol in the treatment of schizophrenia].
The clinical research on Klozapol included 28 patients (17 female and 11 male) diagnosed as suffering from schizophrenia. The drug was tested in open trial without comparison with original medication. This research revealed a high therapeutic effectiveness of Klozapol in roughly 2/3 of the cases. The side effects which have been observed were slight, and occurred with similar frequency as Leponex. The hematological complications such as granulocytopenia and agranulocytosis were not observed. The range of the doses was quite wide between 50 and 900 mg per day.
Kiejna
A
A
Katedry i Kliniki Psychiatrii AM, Wrocławiu.
Borys
J
J
Hein-Antonik
K
K
Baranowski
P
P
D000328:Adult; D003024:Clozapine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017448:Receptors, Dopamine D2 / Q000187:drug effects; D011985:Receptors, Serotonin / Q000187:drug effects; D012559:Schizophrenia / Q000188:drug therapy*; D016896:Treatment Outcome
D017448:Receptors, Dopamine D2; D011985:Receptors, Serotonin; D003024:Clozapine
Ocena kliniczna Klozapolu w leczeniu schizofrenii.