Identification of an allelic variant of isoform MLC1-V/sB (human myosin light chain).
A study of 250 specimens of human myocardium by two-dimensional gel electrophoresis revealed an allelic variant of isoform MLC1-V/sB, which was identified by immunoblotting with monoclonal antibody against MLC1-V/sB and peptide mapping after in situ tryptic digestion of electroblotted proteins. The substitution Asn-144 for His-144 was found in this new allelic variant of MLC1-V/sB.
Laptev
A V
AV
Research Centre of Medical Genetics, Russian Academy of Medical Sciences, Moscow.
Shishkin
S S
SS
Kovalyov
L I
LI
Galyuk
M A
MA
Musolyamov
A Kh
AKh
Egorov
T A
TA
D000483:Alleles; D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D015180:Electrophoresis, Gel, Two-Dimensional; D014644:Genetic Variation; D006801:Humans; D008969:Molecular Sequence Data; D009206:Myocardium / Q000737:chemistry; D009218:Myosins / Q000737:chemistry / Q000235:genetics*
D009218:Myosins