Family study of obsessive-compulsive disorder in a Mexican population.
Twenty seven obsessive-compulsive disorder (OCD) patients were studied at the Instituto Mexicano de Psiquiatría in Mexico City. This is the first sample of OCD patients studied in Latin America. There was a significant sex ratio difference and a significant difference in the type of obsessions and compulsions displayed by males and females. Co-morbidity data demonstrated a high frequency of obsessive-compulsive personality disorders, depression, sexual abuse, suicidal attempts and neurological damage. Approximately one third of OCD cases demonstrated a positive family history. There was a higher than expected frequency of first degree relatives affected with OCD. In addition, this study may support the hypothesis that OCD and tics are genetically related.
Nicolini
H
H
Unidad de Genética Molecular Psiquiátrica PUIS-UNAM, Instituto Mexicano de Psiquiatría, D.F.
Weissbecker
K
K
Mejía
J M
JM
Sánchez de Carmona
M
M
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000235:genetics; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology / Q000235:genetics*; D012737:Sex Factors; D013981:Tic Disorders / Q000235:genetics