title: Malignant growth of a recurrent macroprolactinoma after radiation therapy.
abstract: The authors report a case of a 60-year-old woman with a macroprolactinoma. After radiation therapy of the subtotally excised recurrent tumor, it developed a rapid malignant-destructive growth with invasion into adjacent structures. The causal factors are discussed and the literature is briefly reviewed.
authors.affiliation: Department of Neurosurgery, Martin-Luther-University Halle-Wittenberg, Germany.
authors.forename: N G
authors.initials: NG
authors.lastname: Rainov
authors.forename: W
authors.initials: W
authors.lastname: Burkert
mesh_terms: D001971:Bromocriptine / Q000008:administration & dosage; D002471:Cell Transformation, Neoplastic / Q000528:radiation effects*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008090:Lisuride / Q000008:administration & dosage; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging*; D010910:Pituitary Irradiation; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery; D011388:Prolactin / Q000097:blood; D015175:Prolactinoma / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D001971:Bromocriptine; D011388:Prolactin; D008090:Lisuride