title: [Progress and application of molecular genetics in the research of Mycobacterium tuberculosis].
abstract: In the last decade, a great deal of advances in the genetics of Mycobacterium tuberculosis have been made by the introduction of new genetic technologies. In this review, a brief discussion of the progress in mycobacterial genetics, especially, gene cloning, development of host-vector systems, structural analysis of chromosomal DNA, plasmid DNA and mycobacteriophage DNA, IS element, and drug resistance mechanism was presented.
authors.affiliation: Department of Microbiology, University of Occupational and Environmental Health, Japan, Kitakyushu.
authors.forename: Y
authors.initials: Y
authors.lastname: Mizuguchi
mesh_terms: D006801:Humans; D008967:Molecular Biology; D009169:Mycobacterium tuberculosis / Q000235:genetics*