title: [Epidemic of aseptic meningitis with echovirus type 30 in Gifu Prefecture].
abstract: During July to December in 1991, an epidemic of aseptic meningitis occurred in Gifu Prefecture in children. Epidemiological, virological and serological investigations were performed. The results are as follows: 1) Cases involved ranged from 0 to 13 years of age, and 75.9% of them were in the 3 to 7 year of age group. 2) Three types of enteroviruses were isolated from 83 of 133 cases (62.4%), and the echovirus type 30 was recovered from 71 cases (85.5%). 3) In 1991 with the cross neutralizing test between the prototype and isolated strains of echovirus type 30, a remarkable antigenic variation could not be found. 4) In serological studies, the positive rates of neutralizing antibodies to echovirus type 30 in infant sera aged 0-9 years in 1992-1993, was 51.9% with the prototype strain, but 34.0% with an isolated strain in 1991.
authors.affiliation: Gifu Prefectural Health and Environment Research Center.
authors.forename: C
authors.initials: C
authors.lastname: Miwa
authors.forename: S
authors.initials: S
authors.lastname: Sawatari
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D004457:Echovirus Infections / Q000453:epidemiology*; D029822:Enterovirus B, Human / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008582:Meningitis, Aseptic / Q000453:epidemiology* / Q000382:microbiology; D008587:Meningitis, Viral / Q000453:epidemiology* / Q000382:microbiology