title: [Differentiated treatment of generalized peritonitis].
abstract: The article discusses the results of treatment of 327 patients with generalized peritonitis in the toxic and terminal stages. The patients were divided conditionally into three groups. In the first group (42 patients) treatment consisted in routine cleansing of the abdominal cavity with drainage and introduction of antibiotics into it in the postoperative period. Mortality was 45.7%, complications occurred in 52.6% of patients who had survived. In the second group (145 patients) peritoneal dialysis in the flow-drip regimen was applied 3 or 4 times per 24 hours in a volume of 3-4 liters. In this group mortality was 37.9%, the number of complications among the survivals was 41.1%. In the third group (140 patients) a complex of differentiated peritoneal therapy was employed, including the following developed methods: thorough intraoperative cleansing of the abdominal cavity with 10-15 liters of antiseptic solutions containing antibiotics chosen according to the results of express-bacterioscopy, "active" peritoneal dialysis in the flow-fraction regimen, as well as developed methods of laparostomy--controlled laparostomy, prolonged open administration with local cleansing and use of antibacterial ointments. With use of this complex, mortality reduced to 27.1% and the incidence of complications to 20.6%.
authors.forename: Sh I
authors.initials: ShI
authors.lastname: Karimov
authors.forename: B D
authors.initials: BD
authors.lastname: Babadzhanov
authors.forename: B D
authors.initials: BD
authors.lastname: Durmanov
authors.forename: M S
authors.initials: MS
authors.lastname: Islamov
authors.forename: I A
authors.initials: IA
authors.lastname: Kim
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004322:Drainage; D006801:Humans; D007430:Intraoperative Care; D010530:Peritoneal Dialysis; D010533:Peritoneal Lavage; D010538:Peritonitis / Q000401:mortality / Q000628:therapy*; D011182:Postoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000401:mortality; D015996:Survival Rate
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Differentsirovannaia terapiia pri rasprostranennom peritonite.