title: [A case of bronchogenic squamous cell carcinoma associated with Swyer-James syndrome].
abstract: Swyer-James syndrome is considered to be a relatively uncommon disease entity presenting with unilateral hyperlucent lung due to hypoplasia of a pulmonary artery and bronchiectasis of the affected lung. Association of bronchogenic carcinoma with Swyer-James syndrome has not apparently been reported in any previous literature, except for one Japanese case. In the present paper, we describe a 48-year-old male individual, who developed poorly differentiated squamous cell carcinoma of the right upper lobe bronchus after he had been diagnosed to have Swyer-James syndrome with unilateral hyperradiancy of the left lung. It is suggested that the bronchial epithelium of the unaffected lung in Swyer-James syndrome is likely to be more exposed to extrinsic carcinogens than that of the affected, underventilated lung, hence resulting in a higher risk of developing bronchogenic carcinoma.
authors.affiliation: Department of Internal Medicine II, Daisan Hospital, Jikei University School of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Okada
authors.forename: K
authors.initials: K
authors.lastname: Yoshimura
authors.forename: A
authors.initials: A
authors.lastname: Kojima
authors.forename: H
authors.initials: H
authors.lastname: Hirose
authors.forename: N
authors.initials: N
authors.lastname: Okajima
authors.forename: H
authors.initials: H
authors.lastname: Takeda
authors.forename: I
authors.initials: I
authors.lastname: Kikuchi
authors.forename: H
authors.initials: H
authors.lastname: Tai
authors.forename: T
authors.initials: T
authors.lastname: Tokuda
authors.forename: H
authors.initials: H
authors.lastname: Okano
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000002:abnormalities; D011656:Pulmonary Emphysema / Q000150:complications; D013577:Syndrome; D014057:Tomography, X-Ray Computed