title: Toxocariasis simulating hepatic recurrence in a patient with Wilms' tumor.
abstract: We report the case of a 3-year-old girl with stage I Wilms' tumor of favorable histology. During the course of chemotherapy 5 months post-diagnosis, an abdominal ultrasonogram revealed hypoechoic areas consistent with hepatic tumor recurrence. A liver biopsy performed to rule out recurrence of the malignancy was suggestive of toxocariasis and the diagnosis was confirmed by serologic testing. Although the patient had few classic signs of visceral larva migrans, her eosinophilia and family social history should have suggested this possibility. This case demonstrates that hepatic toxocariasis should be considered in evaluating hepatic hypoechoic lesions in a child, even when features typical of the disease are absent.
authors.affiliation: Instituto da Criança, Hospital das Clinicas, Universidade Estadual de São Paulo, Brazil.
authors.forename: M T
authors.initials: MT
authors.lastname: Almeida
authors.forename: R C
authors.initials: RC
authors.lastname: Ribeiro
authors.forename: W M
authors.initials: WM
authors.lastname: Kauffman
authors.forename: P T
authors.initials: PT
authors.lastname: Maluf Júnior
authors.forename: J L
authors.initials: JL
authors.lastname: Brito
authors.forename: L M
authors.initials: LM
authors.lastname: Cristofani
authors.forename: C A
authors.initials: CA
authors.lastname: Jacob
authors.forename: V
authors.initials: V
authors.lastname: Odone-Filho
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology; D007816:Larva Migrans, Visceral / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008109:Liver Diseases, Parasitic / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000469:parasitology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D013827:Thiabendazole / Q000627:therapeutic use; D014463:Ultrasonography; D009396:Wilms Tumor / Q000000981:diagnostic imaging* / Q000556:secondary*
chemical_list: D013827:Thiabendazole