Hepatitis B virus infection in patients with systemic lupus erythematosus.
Sera from 76 patients with systemic lupus erythematosus (SLE) were examined for HBsAg, anti-HBsAb and total anti-HBcAB by radioimmunoassay. Fifteen patients (19.7%) had one or more of these serological markers of HBV infection. This is comparable to the sero-prevalence in 100 sex- and age-matched healthy individuals (19%). There was no significant difference in the prevalence of HBV infection in patients who had received immunosuppressants compared with those who had not. Patients who had received transfusion of blood or blood products had a higher prevalence of serological markers but this was not statistically significant.
Chng
H H
HH
Department of Rheumatology and Immunology, Tan Tock Seng Hospital, Singapore.
Fock
K M
KM
Chew
C N
CN
Guan
R
R
Feng
P H
PH
Boey
M L
ML
Chee
E N
EN
Chua
K L
KL
D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion; D005260:Female; D006509:Hepatitis B / Q000150:complications* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000097:blood; D006512:Hepatitis B Core Antigens / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications*; D008875:Middle Aged; D015995:Prevalence
D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D007166:Immunosuppressive Agents