title: Hirudin and hirudin-based peptides.
authors.affiliation: MRC Centre, University of Cambridge, United Kingdom.
authors.forename: S R
authors.initials: SR
authors.lastname: Stone
authors.forename: J M
authors.initials: JM
authors.lastname: Maraganore
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002853:Chromatography, Liquid / Q000379:methods; D003001:Cloning, Molecular / Q000379:methods; D004926:Escherichia coli; D006629:Hirudins / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D007202:Indicators and Reagents; D007700:Kinetics; D007865:Leeches; D008433:Mathematics; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D017354:Point Mutation; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D012441:Saccharomyces cerevisiae; D013329:Structure-Activity Relationship; D013917:Thrombin / Q000037:antagonists & inhibitors*
chemical_list: D006629:Hirudins; D007202:Indicators and Reagents; D011994:Recombinant Proteins; D013917:Thrombin