Magnetic resonance spectroscopy and positron emission tomography scanning in neuropsychiatric systemic lupus erythematosus.
Nuclear magnetic resonance spectroscopy (MRS) and positron emission tomography (PET) scanning are the only two non-invasive methods available for obtaining metabolic data on inaccessible tissues such as the brain. MRS and PET scanning are powerful research techniques that provide strong evidence that neuropsychiatric lupus is a brain disorder characterized by profound metabolic alterations including impaired blood flow, ischemia, decreased aerobic metabolism, and progressive neuronal loss.
Sibbitt
W L
WL
Center for Non-invasive Diagnosis, University of New Mexico School of Medicine, Albuquerque.
Sibbitt
R R
RR
D002493:Central Nervous System Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D014055:Tomography, Emission-Computed