title: [Unusual course of glioblastoma multiforme as calcinosis in CCT].
abstract: We report about a rare case of multifocal bihemispheric glioblastoma (WHO grade IV) with unusual course: At time of histological diagnosis via open biopsy and subtotal tumor resection right parieto-occipital the tumorous lesion presents itself for nine months unchanged as a little calcification right parietal, before developing in CCT multiocular bihemispheric hyperdens-hypodens areals with margin contrast enhancement and perifocal edema within one month. Tumor histogenesis of this special case is discussed contrasting the embryogenetic concept with the concept of tumor-grading. From clinical relevance is the fact that even a long time unchanged unifocal calcification in CCT could be the first sign of developing glioblastoma, and so short-term clinical and computer tomographic controls are necessary.
authors.affiliation: Neurochirurgische Klinik, Ruhr-Universität Bochum am Knappschaftskrankenhaus Bochum-Langendreer.
authors.forename: S
authors.initials: S
authors.lastname: Victor
authors.forename: Y
authors.initials: Y
authors.lastname: Altay
authors.forename: T
authors.initials: T
authors.lastname: Schneider
mesh_terms: D001706:Biopsy; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D005909:Glioblastoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009778:Occipital Lobe / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D010296:Parietal Lobe / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
vernacular_title: Ungewöhnliche Verlaufsform eines Glioblastoma multiforme als Verkalkung im CCT.