title: [Four cases of advanced adenocarcinoma showing marked response to EAP (etoposide, ADM, CDDP) treatment].
abstract: Four cases of unresectable adenocarcinoma due to multiple metastasis were treated by EAP (etoposide, ADM, CDDP). The first was a 49-year-old male with gall bladder cancer, who was admitted to the hospital with metastatic umbilical tumor and intraabdominal dissemination. After 2 courses of treatment, the tumor was significantly decreased and the dissemination was diminished. The second was a 42-year-old female of breast cancer, involving lung, adrenal gland and bone metastasis. After 2 courses of treatment, all metastasis responded remarkably. Case 3 was a 42-year-old female with recurrent rectal cancer. Her lung metastasis completely disappeared after EAP treatment. Case 4 was a 42-year-old breast cancer patient with multiple liver metastasis, who also exhibited a remarkable response. In spite of severe side effects, EAP treatment was remarkably effective in all four cases of unresectable advanced adenocarcinoma.
authors.affiliation: Dept. of Surgery, Urayasu Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Iba
authors.forename: Y
authors.initials: Y
authors.lastname: Yagi
authors.forename: A
authors.initials: A
authors.lastname: Kidokoro
authors.forename: M
authors.initials: M
authors.lastname: Fukunaga
authors.forename: T
authors.initials: T
authors.lastname: Fukunaga
authors.forename: S
authors.initials: S
authors.lastname: Mishima
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D005706:Gallbladder Neoplasms / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000188:drug therapy*; D012074:Remission Induction
chemical_list: D005047:Etoposide; D004317:Doxorubicin; D002945:Cisplatin