title: Choroidal melanomas near the optic disk or macula. Long-term results after proton beam irradiation: a report of 3 cases.
abstract: Three patients with choroidal melanomas of the posterior pole were treated with proton beam irradiation. One tumor was medium-sized, two were large-sized. Two of the three eyes were functionally single eyes. 60 CGE (cobalt gray equivalents) was delivered in 4 equal treatments during 4 consecutive days. The minimum follow-up period for each patients is 4 years, the average time 4.8 years. Functionally, we lost both eyes with the large-sized tumors owing to severe radiogenic side effects; the eye containing the largest tumor had to be enucleated after 48 months because of phthisis bulbi. No metastases have developed up to now.
authors.affiliation: First University Eye Clinic, Vienna, Austria.
authors.forename: M
authors.initials: M
authors.lastname: Zehetmayer
authors.forename: R
authors.initials: R
authors.lastname: Menapace
mesh_terms: D000328:Adult; D001766:Blindness / Q000209:etiology; D002830:Choroid Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D015353:Eye Enucleation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008266:Macula Lutea / Q000528:radiation effects; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000532:radiotherapy*; D008875:Middle Aged; D009898:Optic Disk / Q000528:radiation effects; D011832:Radiation Injuries / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects