title: [The relationship between P300 latencies, and WISC-R and Wechsler memory scale results in epileptic children].
abstract: Auditory event-related potentials (ERPs) were recorded in 35 epileptic children of 9 to 13 years of age, and compared with conventional test batteries of cognitive functions. ERPs were elicited with the auditory oddball paradigm. Corrected P300 latencies showed an inverse correlation with the total score (IQ) of WISC-R and that of the Wechsler memory scale (WMS). A strong inverse correlation was also observed with specific items of these test batteries, as follows; "comprehension", "picture completion" and "coding" in WISC-R, and "associated learning", "digit span", "visual reproduction", "mental control", "orientation" and "information" in WMS. These findings suggested that the prolongation of P300 latencies in epileptic children are related with the impairment of cognitive functions. The P300 latency is correlated with a characteristic kind of cognitive function; "simple recognition", "short term memory" and "easy judgement".
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Toyama Medical and Pharmaceutical University.
authors.forename: Y
authors.initials: Y
authors.lastname: Naganuma
authors.forename: T
authors.initials: T
authors.lastname: Konishi
authors.forename: M
authors.initials: M
authors.lastname: Matsui
authors.forename: K
authors.initials: K
authors.lastname: Hongou
authors.forename: M
authors.initials: M
authors.lastname: Murakami
authors.forename: M
authors.initials: M
authors.lastname: Yamatani
authors.forename: T
authors.initials: T
authors.lastname: Okada
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D003071:Cognition; D004827:Epilepsy / Q000523:psychology*; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D007837:Latency Period, Psychological; D008297:Male; D008570:Memory, Short-Term; D014888:Wechsler Scales