title: Management of pterygium with surgery and radiation therapy. The North Florida Pterygium Study Group.
abstract: OBJECTIVE
  To compare our results in the management of pterygium using a higher total dose with other reported results.
  
  
  METHODS
  Between 1971 and 1991, 690 patients were treated with complete surgical excision followed by beta irradiation for primary or recurrent pterygium. Of these patients, 129 had two or more areas involving both eyes for a total of 825 lesions treated. Only 17 patients (2%) had temporal lesions with the rest of the patients having nasal pterygia. All patients underwent complete surgical resection of the pterygium before undergoing radiation therapy. One hundred forty-nine patients had undergone previous surgical resection alone but developed recurrence. After surgical excision, all patients were treated with Strontium-90 applicators starting immediately within 24 hr of surgery. Our standard policy was six weekly applications, each delivering a surface dose of 1000 cGy. The total dose delivered was 6000 cGy. Minimum follow-up was 1 year with a median of greater than 8 years.
  
  
  RESULTS
  There were only fourteen recurrences (1.7%) out of a total of 825 lesions treated. Nine of the fourteen patients received suboptimal therapy undergoing less than five applications of Strontium-90. There were no major complications.
  
  
  CONCLUSIONS
  The combination of surgical excision followed by adequate Strontium-90 applications is highly effective in the management of pterygium. The optimal total dose appears to be in the range of 2000 cGy to 6000 cGy.
authors.affiliation: Williams Cancer Center, Baptist Medical Center, Jacksonville, FL 32207.
authors.forename: S B
authors.initials: SB
authors.lastname: Paryani
authors.forename: W P
authors.initials: WP
authors.lastname: Scott
authors.forename: J W
authors.initials: JW
authors.lastname: Wells
authors.forename: D W
authors.initials: DW
authors.lastname: Johnson
authors.forename: R J
authors.initials: RJ
authors.lastname: Chobe
authors.forename: A
authors.initials: A
authors.lastname: Kuruvilla
authors.forename: S
authors.initials: S
authors.lastname: Schoeppel
authors.forename: A
authors.initials: A
authors.lastname: Deshmukh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011625:Pterygium / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D013326:Strontium Radioisotopes / Q000627:therapeutic use*
chemical_list: D013326:Strontium Radioisotopes