Excessive stimulation is bad, so desensitization is ubiquitous.
Gershergorn
M C
MC
D000302:Adrenal Cortex / Q000378:metabolism / Q000473:pathology; D004702:Endocrine Glands / Q000378:metabolism*; D004700:Endocrine System Diseases / Q000209:etiology*; D019204:GTP-Binding Proteins / Q000378:metabolism*; D006706:Homeostasis; D007545:Isoproterenol / Q000494:pharmacology; D011943:Receptors, Adrenergic, beta / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism*; D015398:Signal Transduction; D013997:Time Factors
D011943:Receptors, Adrenergic, beta; D011956:Receptors, Cell Surface; D019204:GTP-Binding Proteins; D007545:Isoproterenol