Prevalence of microalbuminuria in older-onset diabetes.
OBJECTIVE
To examine the prevalence of microalbuminuria and the relationships of microalbuminuria to blood pressure and other risk factors.


METHODS
Individuals diagnosed with diabetes at > or = 30 yr of age either taking insulin (n = 435) or not taking insulin (n = 363), who were participants in the population-based Wisconsin Epidemiologic Study of Diabetic Retinopathy, were examined during 1984-1986. Random urine samples were collected and an agglutination inhibition test was used to determine the presence of microalbuminuria, which is defined as > or = 0.03 g/L but < 0.3 g/L.


RESULTS
The frequency of microalbuminuria was 29.2% in those individuals taking insulin and 22.0% in those not taking insulin. Microalbuminuria was significantly associated with the male sex, older age, higher systolic blood pressure, higher GHb, use of insulin, higher recent alcohol consumption, and a history of cardiovascular disease.


CONCLUSIONS
These findings suggest a relationship between controllable risk factors, blood pressure and GHb, and microalbuminuria in older-onset diabetic individuals.
Klein
R
R
University of Wisconsin, Department of Ophthalmology, Madison.
Klein
B E
BE
Moss
S E
SE
D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D000419:Albuminuria / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology; D000428:Alcohol Drinking; D001794:Blood Pressure; D002561:Cerebrovascular Disorders / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy / Q000652:urine*; D003930:Diabetic Retinopathy / Q000453:epidemiology; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011507:Proteinuria / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D014922:Wisconsin / Q000453:epidemiology
D007328:Insulin