Divalent cation and lipid-protein interactions of biomembranes.
Divalent cations play an important role in the functions of biomembranes. This review deals with three topics: (1) Mg(2+)-mediated change in physical state of phospholipid induces conformation and activity change of reconstituted mitochondrial H(+)-ATPase, (2) a proper transmembrane Ca2+ gradient is essential for the higher enzymatic activity of adenylate cyclase, and (3) role of transmembrane Ca2+ gradient in the modulation of reconstituted sarcoplasmic reticulum Ca(2+)-ATPase activity.
Yang
F Y
FY
National Laboratory of Biomacromolecules, Institute of Biophysics, Academia Sinica, Beijing, China.
Huang
Y G
YG
Tu
Y P
YP
D000818:Animals; D002413:Cations, Divalent / Q000032:analysis / Q000378:metabolism*; D002462:Cell Membrane / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D007425:Intracellular Membranes / Q000737:chemistry / Q000378:metabolism; D008563:Membrane Lipids / Q000032:analysis / Q000378:metabolism*; D008565:Membrane Proteins / Q000032:analysis / Q000378:metabolism*
D002413:Cations, Divalent; D008563:Membrane Lipids; D008565:Membrane Proteins