Status of different immune cells during regression of a rat histiocytoma.
Status of CD4 and CD8 positive T-lymphocytes, natural killer cells and macrophages has been studied in animals which reject AK-5 histiocytoma. Analysis of immune cells which enter the tumour showed higher number of CD8 positive and NK cells around day 25 after tumour transplantation, suggesting their participation in tumour rejection.
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Centre for Cellular & Molecular Biology, Hyderabad, India.
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Manogaran
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D000818:Animals; D018219:Histiocytoma, Benign Fibrous / Q000276:immunology*; D007694:Killer Cells, Natural / Q000276:immunology; D016246:Lymphocytes, Tumor-Infiltrating / Q000276:immunology; D009365:Neoplasm Regression, Spontaneous / Q000276:immunology*; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000276:immunology