SHORT syndrome and insulin resistance.
We describe a further case of SHORT syndrome. This girl shows nearly all the typical manifestations reported in patients with SHORT syndrome. However, at 14 years she presented with non-ketotic hyperglycemia. At 16 1/2 years, the diagnosis of diabetes mellitus secondary to severe insulin resistance was made by intravenous insulin challenge. Insulin resistant diabetes mellitus seems to be a new finding in SHORT syndrome, not previously described in this condition.
Schwingshandl
J
J
Department of Pediatrics, University of Graz, Austria.
Mache
C J
CJ
Rath
K
K
Borkenstein
M H
MH
D000015:Abnormalities, Multiple / Q000503:physiopathology*; D000293:Adolescent; D001827:Body Height; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D013577:Syndrome