Virulence of Salmonella enteritidis phagetypes 4, 8 and 13 and other Salmonella spp. for day-old chicks, hens and mice.
Virulence of three Canadian poultry strains of Salmonella enteritidis, namely phagetypes (PT) 4, 8 and 13, and one Salmonella heidelberg strain was assessed in orally and intraperitoneally inoculated one-day old chickens and compared to the virulence of a human S. enteritidis PT 4 strain from the United Kingdom (UK). The two PT 4 strains were also compared in orally inoculated adult laying hens. In addition, orally inoculated Balb/c mice were used to evaluate virulence of the above strains and two strains of Salmonella typhimurium containing different plasmids. In orally inoculated one-day old chickens, the UK S. enteritidis PT 4 strain was more virulent than the Canadian PT 4 strain. The UK PT 4 strain was also more virulent and invasive in adult laying hens than the Canadian PT 4 strain. The S. enteritidis PT 8 strain and one S. typhimurium strain isolated from a chicken hatchery were the most virulent for orally inoculated Balb/c mice. This strain of S. typhimurium contained the 60 megadalton plasmid associated with virulence for Balb/c mice which was not present in the S. typhimurium strain isolated from a pig with septicemic disease.
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Agriculture Canada, Health of Animals Laboratory, Guelph, Ontario.
Demczuk
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McFadden
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Johnson
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D000818:Animals; D001434:Bacteriophage Typing; D002432:Cecum / Q000382:microbiology; D002645:Chickens / Q000382:microbiology*; D004195:Disease Models, Animal; D004531:Eggs / Q000382:microbiology; D005260:Female; D005766:Gastrointestinal Contents / Q000382:microbiology; D007928:Lethal Dose 50; D008099:Liver / Q000382:microbiology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011201:Poultry Diseases / Q000382:microbiology*; D012475:Salmonella / Q000472:pathogenicity; D012481:Salmonella Infections, Animal / Q000382:microbiology*; D012477:Salmonella enteritidis / Q000145:classification / Q000472:pathogenicity*; D013154:Spleen / Q000382:microbiology; D014774:Virulence