A new O-acetylated trisialoganglioside, 9-O-acetyl GT2, in cod brain.
An O-acetylated trisialoganglioside that is converted to GT2 on mild base treatment was found in cod brain. This alkali-labile ganglioside was isolated using high-performance liquid chromatography, and its chemical structure was characterized. This novel ganglioside was identified as a GT2 derivative having an acetyl group at the C-9 position of the external sialic acid. Its chemical structure is as follows.
Waki
H
H
Department of Membrane Biochemistry, Tokyo Metropolitan Institute of Gerontology.
Masuzawa
A
A
Kon
K
K
Ando
S
S
D000107:Acetylation; D000818:Animals; D001923:Brain Chemistry; D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D005399:Fishes / Q000378:metabolism*; D005732:Gangliosides / Q000032:analysis* / Q000737:chemistry; D008969:Molecular Sequence Data; D015394:Molecular Structure
D005732:Gangliosides; C085195:9-O-acetyl GT2