[Treatment of chronic non-healing donor sites: transplantation of cultured human fibroblasts].
The authors discuss the first results of the use of cultivated human allofibroblasts in the treatment of persisting wounds of the donor areas in 13 patients with deep burns and cicatricial deformities caused by the burns. Transplantation of cell cultures led to complete epithelialization of the wounds in 6-10 days. Complication, suppuration of the grafted material, was recorded in one case. Reaction of graft rejection was not encountered. The authors believe that the effect of the transplantation is due to stimulation of the epithelialization processes by the cultivated fibroblasts.
Moroz
V Iu
VIu
Grishkevich
V M
VM
Alekseev
A A
AA
Glushchenko
E V
EV
Sarkisov
D S
DS
Gurukov
Sh R
ShR
Tumanov
V P
VP
Morozov
S S
SS
D002056:Burns / Q000150:complications / Q000601:surgery*; D002478:Cells, Cultured; D002908:Chronic Disease; D002921:Cicatrix / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005347:Fibroblasts / Q000637:transplantation*; D006801:Humans; D012086:Reoperation; D016038:Skin Transplantation; D016896:Treatment Outcome; D014945:Wound Healing
Lechenie dlitelńo ne zazhivaiushchikh donorskikh uchastkov: transplan tatsiia kultivirovannykh allofibroblastov cheloveka.