title: Combined modality therapy for locally advanced penile squamous cell carcinoma.
abstract: We report here a patient who presented with locally advanced Jackson Stage IV penile squamous cell carcinoma who was managed with preoperative 5-fluorouracil, mitomycin C chemotherapy, and concurrent radiation therapy. He experienced an excellent partial response which allowed more limited surgery than would otherwise be indicated. He is still alive and well 5 years after completion of his treatment without side effects, local recurrence, or distant metastatic disease.
authors.affiliation: Department of Radiation Oncology, Riverside Regional Cancer Institute, Columbus, OH 43214.
authors.forename: T J
authors.initials: TJ
authors.lastname: Pedrick
authors.forename: W
authors.initials: W
authors.lastname: Wheeler
authors.forename: H
authors.initials: H
authors.lastname: Riemenschneider
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage; D010412:Penile Neoplasms / Q000532:radiotherapy / Q000628:therapy*
chemical_list: D016685:Mitomycin; D005472:Fluorouracil