title: Evaluation of Emit II reagents on the Chem 1.
abstract: An evaluation study of Syva Emit II reagents using the Chem 1 was performed for the following drugs: barbiturates, benzodiazepines, cannabinoids, benzoylecgonine, opiates, and phencyclidine. The Emit II reagents (100-mL bottles) were reconstituted to 70 mL and evaluated against the Emit d.a.u. reagents. A minimum of 446 samples were run for each drug. For all drugs tested, there were a total of 11 discordant results between the two reagents. The Emit II reagent was found to be correct on 8 of the 11 discordances after retesting by FPIA or GC/MS. The CV of within-run and day-to-day precision of the Emit II was 1.8% or less and 12.3% or less, respectively.
authors.affiliation: National Toxicology Laboratories, Inc., Bakersfield, CA 93304.
authors.forename: R C
authors.initials: RC
authors.lastname: Sreenivasam
authors.forename: T C
authors.initials: TC
authors.lastname: Sneath
authors.forename: N C
authors.initials: NC
authors.lastname: Jain
mesh_terms: D001463:Barbiturates / Q000652:urine; D001569:Benzodiazepines / Q000652:urine; D002186:Cannabinoids / Q000652:urine; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D003042:Cocaine / Q000031:analogs & derivatives / Q000652:urine; D005069:Evaluation Studies as Topic; D006801:Humans; D007202:Indicators and Reagents / Q000032:analysis*; D009294:Narcotics / Q000652:urine; D010622:Phencyclidine / Q000652:urine; D015203:Reproducibility of Results
chemical_list: D001463:Barbiturates; D002186:Cannabinoids; D007202:Indicators and Reagents; D009294:Narcotics; D001569:Benzodiazepines; C005618:benzoylecgonine; D003042:Cocaine; D010622:Phencyclidine