Chromosomal localization of the epsilon 1, epsilon 3 and zeta 1 subunit genes of the human NMDA receptor channel.
Partial complementary DNAs for the epsilon 1, epsilon 3 and zeta 1 subunits of the human N-methyl-D-aspartate (NMDA) receptor channel were cloned using the corresponding mouse subunit cDNA clones as probes. Genomic DNA clones for the human epsilon 1, epsilon 3 and zeta 1 subunit genes were isolated using the corresponding partial cDNA clones as probes. By the fluorescence in situ hybridization, we mapped the genes for the epsilon 1, epsilon 3 and zeta 1 subunits of the human NMDA receptor channel to chromosomes 16p13, 17q25 and 9q34, respectively.
Takano
H
H
Department of Neurology, Niigata University, Japan.
Onodera
O
O
Tanaka
H
H
Mori
H
H
Sakimura
K
K
Hori
T
T
Kobayashi
H
H
Mishina
M
M
Tsuji
S
S
D000328:Adult; D002540:Cerebral Cortex / Q000378:metabolism; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D002886:Chromosomes, Human, Pair 17; D002899:Chromosomes, Human, Pair 9; D003001:Cloning, Molecular; D015342:DNA Probes; D018076:DNA, Complementary / Q000378:metabolism; D015723:Gene Library; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D046911:Macromolecular Substances; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics*
D015342:DNA Probes; D018076:DNA, Complementary; D046911:Macromolecular Substances; D016194:Receptors, N-Methyl-D-Aspartate