title: [Pure dysgerminomas of the ovary. Retrospective analysis of 17 cases treated at the Claudius Regaud Center from 1974 to 1989].
abstract: From 1974 to 1989, 17 dysgerminomas of the ovary were treated at the Centre Claudius Regaud. The mean age of the patients was 21 years: 53% were FIGO stage IA, 17% were stage IB, 6% were stage IIB and 24% were stage IIIC. Conservative surgery was performed in 13 patients (unilateral salpingo-oophorectomy) and non-conservative surgery was performed in the others patients. 70% of the patients underwent complete resection. Post-operative treatment was administered in every case but one (radiotherapy: 15 patients; combined chemo-radiotherapy: 1 patient). All patients achieved complete remission after the first-line treatment, but 2 of them recurred (1 IA, 1 IIB). A second remission was achieved in both cases. The overall survival rates were 100% at 2 years, 94% at 5 years and 89% at 10 years. The dual objective of curing the patient of her malignant disease while preserving her reproductive function was achieved in 53% of the patients.
authors.affiliation: Département d'Oncologie Médicale, Centre Claudius Regaud, Toulouse.
authors.forename: I
authors.initials: I
authors.lastname: About
authors.forename: R
authors.initials: R
authors.lastname: Bugat
authors.forename: A
authors.initials: A
authors.lastname: Naja
authors.forename: J F
authors.initials: JF
authors.lastname: David
authors.forename: J
authors.initials: J
authors.lastname: Mihura
mesh_terms: D000206:Actuarial Analysis; D000293:Adolescent; D000328:Adult; D002648:Child; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000401:mortality / Q000628:therapy*; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000401:mortality / Q000628:therapy*; D012074:Remission Induction; D012189:Retrospective Studies
vernacular_title: Dysgerminomes purs de l'ovaire. Analyse rétrospective de dix-sept cas traités au Centre Cladius Regaud de 1974 à 1989.