title: Tumour induction by transplacental infection with polyoma virus of the F1 generation of Wistar rats.
abstract: Intravenous polyoma virus inoculation into pregnant Wistar rats resulted in transplacental infection of the foetus, causing tumours and hydronephroses. Cyclosporin A reduced these effects significantly.
authors.affiliation: Institute of Virology, Medical School of Hannover, Federal Republic of Germany.
authors.forename: W
authors.initials: W
authors.lastname: Verhagen
authors.forename: C M
authors.initials: CM
authors.lastname: Hubert
authors.forename: E
authors.initials: E
authors.lastname: Mohtaschem
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000097:blood; D001739:BK Virus / Q000276:immunology / Q000472:pathogenicity*; D016572:Cyclosporine / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D005315:Fetal Diseases / Q000209:etiology* / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006391:Hemangioma / Q000209:etiology; D006869:Hydronephrosis / Q000209:etiology; D007165:Immunosuppression Therapy; D007680:Kidney Neoplasms / Q000209:etiology; D009423:Nervous System Neoplasms / Q000209:etiology; D030361:Papillomavirus Infections / Q000276:immunology / Q000635:transmission*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D012513:Sarcoma, Experimental / Q000209:etiology; D014412:Tumor Virus Infections / Q000276:immunology / Q000635:transmission*
chemical_list: D000914:Antibodies, Viral; D016572:Cyclosporine