title: [Extracorporal and endogenous detoxication in appendicular peritonitis in children].
abstract: The article deals with the method for detoxification of patients with diffuse and generalized peritonitis. Exogenous detoxification was accomplished by the open method for peritonitis management (laparotomy), endogenous detoxification was achieved by well-founded intraperitoneal and intravenous administration of proteolysis inhibitors. Comparison of the two groups of patients who were operated on showed marked reduction of mortality from 22.2% to 2.7% in generalized peritonitis and from 9.6% to zero in diffuse peritonitis.
authors.forename: Ia B
authors.initials: IaB
authors.lastname: Iudin
authors.forename: Iu D
authors.initials: IuD
authors.lastname: Prokopenko
mesh_terms: D001064:Appendicitis / Q000150:complications; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D010447:Peptide Hydrolases / Q000627:therapeutic use*; D010538:Peritonitis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D016060:Sorption Detoxification
chemical_list: D010447:Peptide Hydrolases
vernacular_title: Ekstrakorporalńaia i éndogennaia detoksikatsiia pri appendikuliarnom peritonite u deteĭ.