title: First-episode mania in late life.
abstract: Among 14 elderly patients (mean age = 74.6 years) with first-episode mania who were followed for 3 to 10 years, men had a higher risk of mortality. Compared to 36 elderly patients with multiple episodes of mania, patients with first-episode mania were twice as likely to have a comorbid neurological disorder (71% [N = 10] versus 28% [N = 10]). Mania in the elderly appears to be a heterogeneous disorder.
authors.affiliation: Bipolar Program, McLean Hospital, Belmont, MA 02178.
authors.forename: M
authors.initials: M
authors.lastname: Tohen
authors.forename: K I
authors.initials: KI
authors.lastname: Shulman
authors.forename: A
authors.initials: A
authors.lastname: Satlin
mesh_terms: D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000401:mortality; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies