title: Antibody-induced alterations of Na+/K(+)-ATPase activity in rabbit red blood cells during experimental thyroglobulin immunization.
abstract: Thyroid hormone modulates cell membrane Na+/K(+)-ATPase. A detailed study of erythrocyte membrane Na+/K(+)-ATPase activity was carried out during experimental thyroglobulin immunization. During the process of immunization there was a sharp decline in Na+/K(+)-ATPase activity until the 98th day of immunization, when the thyroglobulin antibody titer was at its peak. This enzyme activity retained a lower level although a fall in antibody titer occurred up to the 147th day.
authors.affiliation: Department of Gastroenterology, Osmania General Hospital, Hyderabad, India.
authors.forename: C M
authors.initials: CM
authors.lastname: Habibullah
authors.forename: M
authors.initials: M
authors.lastname: Swamy
authors.forename: S
authors.initials: S
authors.lastname: Lahiri
mesh_terms: D000818:Animals; D000906:Antibodies / Q000097:blood*; D004910:Erythrocyte Membrane / Q000201:enzymology*; D007114:Immunization; D008297:Male; D011817:Rabbits / Q000276:immunology; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood* / Q000276:immunology; D013954:Thyroglobulin / Q000276:immunology* / Q000494:pharmacology
chemical_list: D000906:Antibodies; D013954:Thyroglobulin; D000254:Sodium-Potassium-Exchanging ATPase