Carbamazepine and zonisamide increase extracellular dopamine and serotonin levels in vivo, and carbamazepine does not antagonize adenosine effect in vitro: mechanisms of blockade of seizure spread.
Kaneko
S
S
Department of Neuropsychiatry, Hirosaki University.
Okada
M
M
Hirano
T
T
Kondo
T
T
Otani
K
K
Fukushima
Y
Y
D000241:Adenosine / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D015220:Calcium Channels / Q000187:drug effects / Q000502:physiology; D002220:Carbamazepine / Q000494:pharmacology*; D046508:Culture Techniques; D004298:Dopamine / Q000378:metabolism*; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D006624:Hippocampus / Q000187:drug effects / Q000503:physiopathology; D007555:Isoxazoles / Q000494:pharmacology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012640:Seizures / Q000503:physiopathology*; D012701:Serotonin / Q000378:metabolism*; D009435:Synaptic Transmission / Q000187:drug effects* / Q000502:physiology; D000078305:Zonisamide
D000927:Anticonvulsants; D015220:Calcium Channels; D007555:Isoxazoles; D012701:Serotonin; D002220:Carbamazepine; D000078305:Zonisamide; D000241:Adenosine; D004298:Dopamine