[Synthesis and antimicrobial properties of methyl 3-O-alkyl-glucopyranosides].
A new type of nonionic surface-active agents containing sugars as the hydrophilic group were synthesized and evaluated for their antimicrobial activity. Methyl 6-deoxy-3-O-dodecyl-6-halo-D-glucopyranoside derivatives showed powerful antimicrobial activity, but no significant differences were observed on the activity with regard to the kinds of anomers as well as halogen atoms.
Yago
K
K
Department of Pharmacy, Kitasato University Hospital, School of Hygienic Science, Sagamihara, Japan.
Kawada
K
K
Uchibori
T
T
Zen
S
S
Tomonaga
F
F
D001419:Bacteria / Q000187:drug effects*; D005960:Glucosides / Q000138:chemical synthesis* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
D005960:Glucosides