title: Computed tomography of spontaneous intracranial haemorrhage due to haemostatic disorders in children.
abstract: Intracranial haemorrhage is a serious problem in haemostatic disorders in children. Intracranial bleeding is sometimes more marked than suspected clinically. Computed tomography (CT) permits accurate, sensitive diagnosis of intracranial haemorrhage. We report 13 patients; 3 patients with hypoprothrombinaemia, 4 patients with thrombocytopenia or platelet dysfunction and 6 with haemophilia A, B or Von-Willebrand's disease. One patient with hypoprothrombinaemia had a subarachnoid hemorrhage (SAH), one a subdural haematoma (SDH) and the third a combination of SAH, SDH and intracerebral haematoma (ICH). One patient with thrombocytopenia or platelet dysfunction had a SDH, while the others had ICH. In the six patients with haemophilia A, B or Von-Willebrand's disease, there were four examples of ICH, five of SAH and six of SDH. A neurosurgical procedure was performed in only one patient. Three children died of serious intracranial complications with uncal herniation.
authors.affiliation: Department of Radiology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: S L
authors.initials: SL
authors.lastname: Shih
authors.forename: J C
authors.initials: JC
authors.lastname: Lin
authors.forename: D C
authors.initials: DC
authors.lastname: Liang
authors.forename: J K
authors.initials: JK
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000818:Animals; D001778:Blood Coagulation Disorders / Q000150:complications*; D001791:Blood Platelet Disorders / Q000150:complications*; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging* / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007223:Infant; D008297:Male; D014057:Tomography, X-Ray Computed