Biphenylyl-substituted xanthones: highly potent leukotriene B4 receptor antagonists.
Sawyer
J S
JS
Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana 46285.
Baldwin
R F
RF
Sofia
M J
MJ
Floreancig
P
P
Marder
P
P
Saussy
D L
DL
Froelich
L L
LL
Silbaugh
S A
SA
Stengel
P W
PW
Cockerham
S L
SL
D000818:Animals; D016084:Bronchoconstriction / Q000187:drug effects; D002462:Cell Membrane / Q000378:metabolism; D006168:Guinea Pigs; D006801:Humans; D007975:Leukotriene B4 / Q000494:pharmacology; D008168:Lung / Q000378:metabolism; D015394:Molecular Structure; D009504:Neutrophils / Q000378:metabolism; D010636:Phenols / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology*; D018102:Receptors, Leukotriene B4 / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D014966:Xanthenes / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology*
D010636:Phenols; D018102:Receptors, Leukotriene B4; D014966:Xanthenes; C084688:LY 292728; D007975:Leukotriene B4