title: Prognostic value of the tall cell variety of papillary cancer of the thyroid.
abstract: We analyse a new variety of papillary carcinoma of the thyroid, known as the tall cell variant. The lesion is characterized by a papillary cancer (PCT) in which more than 30% of the tumour is made up of a population of tall columnar cells over twice as tall as their width. Of a population of 158 differentiated thyroid carcinomas we found five cases of this rare variant. We studied their clinico-pathological features, the importance of an early diagnosis and their prognostic implications. The data were compared with those of Well-Differentiated or Classical PCT (WDPC), the most important features of which were: (a) later age of appearance; (b) greater predilection for males; (c) greater frequency of extrathyroid tumor extensions; (d) greater frequency of recurrences; and (e) a shorter survival or disease-free interval. The prognostic importance involved in recognizing this variant is based on the need to give patients a more aggressive treatment and more exhaustive follow-up.
authors.affiliation: Department of Surgery, Virgen de la Arrixaca Hospital, Murcia, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Moreno Egea
authors.forename: J M
authors.initials: JM
authors.lastname: Rodriguez Gonzalez
authors.forename: J
authors.initials: J
authors.lastname: Sola Perez
authors.forename: T
authors.initials: T
authors.lastname: Soria Cogollos
authors.forename: P
authors.initials: P
authors.lastname: Parrilla Paricio
mesh_terms: D000368:Aged; D002291:Carcinoma, Papillary / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D013223:Statistics as Topic; D016019:Survival Analysis; D013964:Thyroid Neoplasms / Q000473:pathology*