[The correction of postvagotomy disorders of the motor function in the small intestine by using antihypoxants and antioxidants].
Study of the electric activity of small intestine smooth muscle in vagotomized rats demonstrated diminution and disturbance of intestinal motility. These changes were most expressed within 30 days after vagotomy. Injection of antihypoxant sodium gamma-oxybutyrate and antioxidant dibunol to the vagotomized rats resulted in normalization of intestinal motility.
Ettinger
A P
AP
Tsibulevskiĭ
A Iu
AIu
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use; D002084:Butylated Hydroxytoluene / Q000494:pharmacology / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D004576:Electromyography; D005769:Gastrointestinal Motility / Q000187:drug effects* / Q000502:physiology; D000860:Hypoxia / Q000188:drug therapy* / Q000503:physiopathology; D007421:Intestine, Small / Q000187:drug effects* / Q000294:innervation* / Q000502:physiology; D008297:Male; D009130:Muscle, Smooth / Q000187:drug effects / Q000294:innervation / Q000502:physiology; D051381:Rats; D012978:Sodium Oxybate / Q000494:pharmacology / Q000627:therapeutic use; D013997:Time Factors; D015167:Vagotomy, Truncal; D014630:Vagus Nerve / Q000502:physiology*
D000975:Antioxidants; D002084:Butylated Hydroxytoluene; D012978:Sodium Oxybate
Korrektsiia postvagotomicheskikh barusheniĭ dvigatel'noĭ funktsii tonkoĭ kishki s pomoshch'iu antigipoksantov i antioksidantov.