Effects of exogenous gangliosides on learning and memory in rats.
After 10 or more consecutive daily injections (I.P. 50 mg/kg for developing, adult and aged, 2.5 mg/mouse for neonatal) of total bovine gangliosides, rats were trained to perform the discrimination tasks. The results show that gangliosides can enhance the learning ability and memory retention in rats at different ages.
Mei
Z T
ZT
Shanghai Institute of Physiology, Chinese Academy of Sciences.
Zheng
J Z
JZ
D000375:Aging / Q000523:psychology; D000818:Animals; D000831:Animals, Newborn; D002417:Cattle; D003216:Conditioning, Operant / Q000187:drug effects; D004193:Discrimination Learning / Q000187:drug effects; D004597:Electroshock; D005260:Female; D005502:Food; D005732:Gangliosides / Q000494:pharmacology*; D007858:Learning / Q000187:drug effects*; D008297:Male; D008568:Memory / Q000187:drug effects*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012201:Reward; D013016:Sound; D013268:Stimulation, Chemical
D005732:Gangliosides