title: Cat scratch disease in the United States: an analysis of three national databases.
abstract: OBJECTIVE
  Current knowledge of the epidemiology of cat scratch disease is based primarily on information from case series. We used three national databases to obtain more representative data to determine the incidence and demographics of cat scratch disease.
  
  
  METHODS
  Records coded with the diagnosis of cat scratch disease from two hospital discharge databases and an ambulatory care database were analyzed. Costs of diagnostic tests and hospitalization were obtained from a sample of providers and published data.
  
  
  RESULTS
  The incidence of patients discharged from hospitals with a diagnosis of cat scratch disease was between 0.77 and 0.86 per 100,000 population per year. Fifty-five percent of the case patients were 18 years of age or younger. Males accounted for 60% of cases. Incidence varied by season; approximately 60% of case patients were discharged in the months September through January. The estimated incidence of disease in ambulatory patients was 9.3 per 100,000 population per year. On the basis of these rates, we estimated the annual health care cost of the disease to be more than $12 million.
  
  
  CONCLUSIONS
  The rates and seasonality of cat scratch disease found in this study were consistent with previous reports. Adults represented a higher percentage of the total than reported in previous case series, suggesting that the disease may affect more adults than previously recognized.
authors.affiliation: Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333.
authors.forename: L A
authors.initials: LA
authors.lastname: Jackson
authors.forename: B A
authors.initials: BA
authors.lastname: Perkins
authors.forename: J D
authors.initials: JD
authors.lastname: Wenger
mesh_terms: D000043:Abstracting and Indexing; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000553:Ambulatory Care / Q000706:statistics & numerical data; D002372:Cat-Scratch Disease / Q000175:diagnosis / Q000191:economics / Q000453:epidemiology* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D003937:Diagnosis, Differential; D005260:Female; D017048:Health Care Costs; D006760:Hospitalization / Q000191:economics / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge / Q000706:statistics & numerical data; D011159:Population Surveillance; D012111:Residence Characteristics; D012621:Seasons; D012737:Sex Factors; D014481:United States / Q000453:epidemiology