title: [Topical treatment of oral bleeding in children with clotting disturbances].
abstract: Owing to substitutive therapy an inhibition is possible of bleeding from oral mucosa as well as stomatological procedures in children with haemorrhagic diathesis. For elimination or limiting of substitutive therapy in 29 children with congenital haemorrhagic diathesis caused by plasma or platelet disorders, tissue glue was used. The preparation Tissucol, IMMUNO, was given during 37 stomatological procedures in which 44 tooth were extracted, and for post-traumatic bleeding from oral mucosa. Very good and good results were obtained in 95% of the performed stomatological procedures. That makes possible a statement that Tissucol is effective in maintaining of local haemostasis in children with haemorrhagic diathesis. This method is safer and less expensive than blood-derived preparations used for substitutive therapy, and is especially valuable in the treatment of children with haemophilia type A with antibodies against factor VIII.
authors.affiliation: Kliniki i Katedry Pediatrii, Hematologii i Onkologii Ak. Med., Warszawie.
authors.forename: H
authors.initials: H
authors.lastname: Gazda
authors.forename: A
authors.initials: A
authors.lastname: Grabowska
mesh_terms: D000287:Administration, Topical; D001778:Blood Coagulation Disorders / Q000150:complications / Q000151:congenital; D002648:Child; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006474:Hemorrhagic Disorders / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D006472:Oral Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D014081:Tooth Extraction / Q000009:adverse effects
chemical_list: D015718:Fibrin Tissue Adhesive
vernacular_title: Miejscowe leczenie krwawień z jamy ustnej u dzieci z zaburzeniami krzepniecia.