title: Sinus neoplasia.
abstract: After an overview of the epidemiology, histology, and evaluation of nasal and sinus neoplasms, this article discusses surgical advances in facial translocation, skull base dissection, and defect reconstruction. With the aforementioned, the question of what is technically resectable vs what is curable has become an important but as yet unanswered question. Radiation therapy, combined with surgery or as palliation, presents special challenges in the head and neck, and ports must be carefully defined to minimize damage to vision and adjacent cranial structures. Chemotherapy is usually reserved for palliation, though some report favorable results with induction treatment of squamous cell carcinomas with platin-based regimens.
authors.affiliation: Department of Otolaryngology and Communicative Sciences, Medical University of South Carolina, Charleston.
authors.forename: J D
authors.initials: JD
authors.lastname: Osguthorpe
mesh_terms: D006801:Humans; D008722:Methods; D010255:Paranasal Sinus Neoplasms / Q000532:radiotherapy / Q000601:surgery*