title: The DNA sequence of adenovirus type 40.
abstract: The 34,214 bp DNA sequence of adenovirus type 40 strain Dugan was determined directly from random fragments of virion DNA cloned into a bacteriophage M13 cloning vector. The gene layout is similar to that of other human adenoviruses, and in addition contains two potential protein-coding regions that are conserved, but have not been recognized previously, in other adenovirus genomes. One is oriented rightward, contained within the intron in the protein-coding region for the L4 33K gene, and would encode a protein sharing N-terminal sequence with 33K. The other is a leftward oriented exon located between the E3 and L5 IV (fibre) regions which would specify the N terminus of a novel protein. The region encoding the C terminus of this protein is not apparent from sequence data.
authors.affiliation: MRC Virology Unit, University of Glasgow, U.K.
authors.forename: A J
authors.initials: AJ
authors.lastname: Davison
authors.forename: E A
authors.initials: EA
authors.lastname: Telford
authors.forename: M S
authors.initials: MS
authors.lastname: Watson
authors.forename: K
authors.initials: K
authors.lastname: McBride
authors.forename: V
authors.initials: V
authors.lastname: Mautner
mesh_terms: D000260:Adenoviruses, Human / Q000235:genetics*; D001482:Base Composition; D001483:Base Sequence; D016384:Consensus Sequence; D005814:Genes, Viral; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics*; D015678:Viral Structural Proteins / Q000235:genetics
chemical_list: D014764:Viral Proteins; D015678:Viral Structural Proteins