[Neuropathy caused by necrotizing vasculitis in HIV-1 infection].
A 33 year-old male homosexual infected with human immunodeficiency virus type I developed an asymmetrical and painful neuropathy in the lower limbs. Neuro-muscular biopsy showed a necrotizing vasculitis. There were no clinical features indicative of systemic vasculitis. Prednisone therapy dramatically improved the neuropathy, without adverse effects. Although rare, necrotizing arteritis must be considered in HIV-1 patients with neuropathy, especially in case of mononeuropathy multiplex and when immunodepression is mild or absent, since a successful corticosteroid therapy can be prescribed.
Chamouard
J M
JM
Service de Neurologie, Hôpital de la Salpêtrière, Paris.
Smadja
D
D
Chaunu
M P
MP
Bouche
P
P
D000328:Adult; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006801:Humans; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D011241:Prednisone / Q000627:therapeutic use; D014657:Vasculitis / Q000150:complications / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
D011241:Prednisone
Neuropathie par vasculite nécrosante au cours de l'infection par le VIH1.