title: Structural repeats in cyclosporin A.
abstract: The conformation of various dipeptides of free and cyclophilin A-bound cyclosporin A were compared. Cyclosporin A was shown to contain in both states conformationally duplicated fragments in the putative binding sites for cyclophilin A and phosphatase calcineurin.
authors.affiliation: Institute of Immunology, Lyubuchany, Moscow Region, Russia.
authors.forename: A I
authors.initials: AI
authors.lastname: Denesyuk
authors.forename: J
authors.initials: J
authors.lastname: Lundell
authors.forename: A
authors.initials: A
authors.lastname: Goldman
authors.forename: V P
authors.initials: VP
authors.lastname: Zav'yalov
authors.forename: T
authors.initials: T
authors.lastname: Korpela
mesh_terms: D000591:Amino Acid Isomerases / Q000378:metabolism; D000595:Amino Acid Sequence; D001665:Binding Sites; D002352:Carrier Proteins / Q000378:metabolism; D016572:Cyclosporine / Q000737:chemistry* / Q000378:metabolism; D004151:Dipeptides / Q000737:chemistry; D008958:Models, Molecular; D019696:Peptidylprolyl Isomerase; D011485:Protein Binding; D011487:Protein Conformation
chemical_list: D002352:Carrier Proteins; D004151:Dipeptides; D016572:Cyclosporine; D000591:Amino Acid Isomerases; D019696:Peptidylprolyl Isomerase