Cholinergic neurons contain Calbindin-D28k in the monkey medial septal nucleus and nucleus of the diagonal band: an immunocytochemical study.
The distribution patterns of choline acetyltransferase (CAT), as a marker for cholinergic neurons, and Calbindin-D28k (CaBP) immunoreactivities in the forebrain basal ganglia of the Japanese monkey Macaca fuscata were compared. Similar distribution patterns of CAT and CaBP immunoreactivities were found in the medial septal nucleus (MS) and the nucleus of the diagonal band of Broca (DBB). Double-labeling fluorescence immunocytochemistry revealed that most, but not all, cholinergic neurons were CaBP-immunoreactive in the MS and DBB. The results suggest that CaBP may play a role in the septohippocampal cholinergic neuron system of the monkey.
Ichitani
Y
Y
Institute of Psychology and Behavioral Neuroscience, University of Tsukuba, Ibaraki, Japan.
Tanaka
M
M
Okamura
H
H
Ibata
Y
Y
D000818:Animals; D064026:Calbindins; D002795:Choline O-Acetyltransferase / Q000032:analysis*; D005260:Female; D005625:Frontal Lobe / Q000737:chemistry* / Q000166:cytology; D007124:Immunoenzyme Techniques; D008251:Macaca; D008297:Male; D009474:Neurons / Q000737:chemistry*; D064030:S100 Calcium Binding Protein G / Q000032:analysis*; D012686:Septal Nuclei / Q000737:chemistry* / Q000166:cytology
D064026:Calbindins; D064030:S100 Calcium Binding Protein G; D002795:Choline O-Acetyltransferase