title: A case of polymyositis in a patient with primary biliary cirrhosis treated with D-penicillamine.
abstract: Although D-penicillamine has been used for many rheumatologic diseases, toxicity limits its usefulness in many patients. Polymyositis/dermatomyositis can develop as one of the autoimmune complications of D-penicillamine treatment, but its exact pathogenesis remains unclear. We report a patient with primary biliary cirrhosis, who developed polymyositis while receiving D-penicillamine therapy. We described the special clinical course of the patient. Patients receiving D-penicillamine therapy should be followed carefully for the development of autoimmune complications like polymyositis/dermatomyositis.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Ahn
authors.forename: T H
authors.initials: TH
authors.lastname: Kim
authors.forename: K R
authors.initials: KR
authors.lastname: Peck
authors.forename: Y W
authors.initials: YW
authors.lastname: Song
mesh_terms: D001327:Autoimmune Diseases / Q000139:chemically induced; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000188:drug therapy*; D008875:Middle Aged; D010396:Penicillamine / Q000009:adverse effects*; D017285:Polymyositis / Q000139:chemically induced*
chemical_list: D010396:Penicillamine