Introduction and history of the use of electroencephalography in animal drug studies.
A brief review of the development and the state-of-the-art of EEG methods used to study drug effects is presented. Classification systems based on drug effects in animals kept awake artificially, and based on drug effects on the sleep-wake state duration and distribution are discussed. It is concluded that the techniques are there and the time is ripe to develop animal EEG-based drug classification systems with high predictive ability.
van Riezen
H
H
Research and Development Department, Pharmaceuticals Division Ciba-Geigy Ltd., Basel, Switzerland.
Glatt
A F
AF
D000818:Animals; D004569:Electroencephalography / Q000187:drug effects / Q000266:history*; D049673:History, 20th Century; D011619:Psychotropic Drugs / Q000145:classification / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects
D011619:Psychotropic Drugs