title: Aseptic meningoencephalitis in primary Sjögren's syndrome. Response to plasmapheresis and absence of CNS vasculitis at autopsy.
abstract: It has been suggested that cerebral vasculitis is the pathogenetic mechanism of the central nervous system manifestations of primary Sjögren's syndrome. We present a fatal case of aseptic meningoencephalitis in an 18-year-old woman with primary Sjögren's syndrome in whom there was no evidence of cerebral vasculitis at autopsy. On two occasions her condition improved markedly following plasmapheresis.
authors.affiliation: Clinical Neurosciences Department, St. Vincent's Hospital, Melbourne, Victoria, Australia.
authors.forename: R P
authors.initials: RP
authors.lastname: Gerraty
authors.forename: P A
authors.initials: PA
authors.lastname: McKelvie
authors.forename: E
authors.initials: E
authors.lastname: Byrne
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008590:Meningoencephalitis / Q000150:complications / Q000473:pathology* / Q000628:therapy; D010956:Plasmapheresis; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012859:Sjogren's Syndrome / Q000150:complications / Q000473:pathology* / Q000628:therapy; D014657:Vasculitis / Q000473:pathology*
chemical_list: D003520:Cyclophosphamide; D011239:Prednisolone