title: Management of depression. Current options for this highly treatable disorder.
abstract: Depression is a common disorder that leads to substantial functional impairment and even death if untreated. Suicide rates in persons with untreated major depression can be as high as 30%. However, the disorder is treatable; pharmacotherapy in combination with psychotherapy is effective in up to 90% of patients. Established diagnostic criteria enable physicians to differentiate major depression from other psychiatric disorders and from somatic conditions that may mimic depression. Current treatment options include traditional antidepressant medications as well as the newer serotonin-reuptake inhibitors. Successful treatment depends on administration of an appropriate dose for an adequate duration.
authors.affiliation: Middletown Psychiatric Center, New York.
authors.forename: L
authors.initials: L
authors.lastname: Citrome
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003863:Depression / Q000175:diagnosis / Q000188:drug therapy* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008487:Medical History Taking; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use; D011613:Psychotherapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
chemical_list: D000928:Antidepressive Agents; D008996:Monoamine Oxidase Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors