Trypanosoma cruzi-heart muscle cell interaction: the presence of two or more trypomastigotes within a single endocytic vacuole.
Ultrastructural studies of the interaction between T. cruzi clone Dm28c and heart muscle cells (HMC) showed that in the initial phase of the cell recognition process several parasites could be found attached to a focal point on the surface of the host cell. Immediately following this phase, two or more parasites could be detected inside the same endocytic vacuole by electron spectroscopic imaging (ESI).
Barbosa
H S
HS
Department of Ultrastructure and Cellular Biology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Carvalho
E L
EL
Ferreira
C F
CF
Meirelles
M N
MN
D000818:Animals; D004705:Endocytosis; D006321:Heart / Q000469:parasitology*; D006790:Host-Parasite Interactions; D008855:Microscopy, Electron, Scanning; D009206:Myocardium / Q000473:pathology / Q000648:ultrastructure*; D014349:Trypanosoma cruzi / Q000472:pathogenicity / Q000648:ultrastructure*; D014617:Vacuoles / Q000469:parasitology / Q000648:ultrastructure*