Thiazohalostatin, a new cytoprotective substance produced by Actinomadura. II. Physico-chemical properties and structure determination.
Thiazohalostatin is a new cytoprotective substance produced by Actinomadura sp. HQ24. Its structure was elucidated as shown in Fig. 1 by NMR spectral analyses and chemical modifications. Thiazohalostatin was found to possess a novel skeleton containing trichloropyrrole and thiazoline ring moieties.
Shindo
K
K
Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd., Gunma, Japan.
Yamagishi
Y
Y
Kawai
H
H
D000191:Actinomycetaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D011758:Pyrroles / Q000737:chemistry*; D013053:Spectrophotometry; D013844:Thiazoles / Q000737:chemistry*
D011758:Pyrroles; D013844:Thiazoles; C085028:thiazohalostatin