Aliphatic 1,2-alkanolamines--inhibitors of beta-glucanase from Candida utilis.
Aliphatic 1,2-alkanolamines inhibited beta-glucanase from Candida utilis. The highest inhibitory effect was observed with 1-dodecylamino-3-chloro-2-propanol (Ki = 1.0 mumol/L) and it was much higher than that of D-glucono-delta-lactone. Simple 1,2-alkanolamines, like 2-aminoethanol or 2-methylaminoethanol, did not exhibit any significant inhibitory effect.
Steiner
B
B
Institute of Chemistry, Slovak Academy of Sciences, Bratislava.
Omelková
J
J
Proksa
B
B
Sasinková
V
V
Koós
M
M
D000605:Amino Alcohols / Q000494:pharmacology*; D002175:Candida / Q000201:enzymology*; D005960:Glucosides / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors*
D000605:Amino Alcohols; D005960:Glucosides; C025193:4-nitrophenyl beta-D-glucoside; D006026:Glycoside Hydrolases