Effect of xylene, toluene and methyl alcohol on liver collagenesis in rats.
Among the three important industrial solvents used, maximum stimulation of collagen formation in rat liver was caused by methyl alcohol followed by toluene and xylene. A combined treatment also promoted collagenesis suggesting a synergistic effect of these solvents.
Rana
S V
SV
Department of Zoology, Meerut University, India.
Kumar
S
S
D000818:Animals; D003094:Collagen / Q000096:biosynthesis*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D000432:Methanol / Q000633:toxicity; D051381:Rats; D012997:Solvents / Q000633:toxicity*; D014050:Toluene / Q000633:toxicity; D014992:Xylenes / Q000633:toxicity
D012997:Solvents; D014992:Xylenes; D014050:Toluene; D003094:Collagen; D000432:Methanol