Lineage-dependent mating-type transposition in fission and budding yeast.
The basis of cellular differentiation is perhaps best understood in the yeast mating-type switching system. The yeast cell produces daughter cells that differ from each other or from their parent cell via developmentally regulated genomic rearrangements. Recent experiments on cell-type determination in fission yeast have revealed that this process is determined by the inheritance of specific parental chromosome strands by the progeny cells.
Klar
A J
AJ
Laboratory of Eukaryotic Gene Expression, NCI-Frederick Cancer Research and Development Center, Maryland 21702-1201.
D004251:DNA Transposable Elements; D005800:Genes, Fungal; D049770:Genes, Mating Type, Fungal; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D012568:Schizosaccharomyces / Q000235:genetics*
D004251:DNA Transposable Elements