[A case of bronchogenic squamous cell carcinoma associated with Swyer-James syndrome].
Swyer-James syndrome is considered to be a relatively uncommon disease entity presenting with unilateral hyperlucent lung due to hypoplasia of a pulmonary artery and bronchiectasis of the affected lung. Association of bronchogenic carcinoma with Swyer-James syndrome has not apparently been reported in any previous literature, except for one Japanese case. In the present paper, we describe a 48-year-old male individual, who developed poorly differentiated squamous cell carcinoma of the right upper lobe bronchus after he had been diagnosed to have Swyer-James syndrome with unilateral hyperradiancy of the left lung. It is suggested that the bronchial epithelium of the unaffected lung in Swyer-James syndrome is likely to be more exposed to extrinsic carcinogens than that of the affected, underventilated lung, hence resulting in a higher risk of developing bronchogenic carcinoma.
Okada
M
M
Department of Internal Medicine II, Daisan Hospital, Jikei University School of Medicine.
Yoshimura
K
K
Kojima
A
A
Hirose
H
H
Okajima
N
N
Takeda
H
H
Kikuchi
I
I
Tai
H
H
Tokuda
T
T
Okano
H
H
D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000002:abnormalities; D011656:Pulmonary Emphysema / Q000150:complications; D013577:Syndrome; D014057:Tomography, X-Ray Computed