title: (1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide.
authors.affiliation: SmithKline Beecham Pharmaceuticals, Harlow, Essex, England.
authors.forename: L M
authors.initials: LM
authors.lastname: Gaster
authors.forename: A J
authors.initials: AJ
authors.lastname: Jennings
authors.forename: G F
authors.initials: GF
authors.lastname: Joiner
authors.forename: F D
authors.initials: FD
authors.lastname: King
authors.forename: K R
authors.initials: KR
authors.lastname: Mulholland
authors.forename: S K
authors.initials: SK
authors.lastname: Rahman
authors.forename: S
authors.initials: S
authors.lastname: Starr
authors.forename: P A
authors.initials: PA
authors.lastname: Wyman
authors.forename: K A
authors.initials: KA
authors.lastname: Wardle
authors.forename: E S
authors.initials: ES
authors.lastname: Ellis
mesh_terms: D000818:Animals; D004146:Dioxanes / Q000138:chemical synthesis* / Q000494:pharmacology; D006168:Guinea Pigs; D008787:Metoclopramide / Q000031:analogs & derivatives; D009119:Muscle Contraction / Q000187:drug effects; D010880:Piperidines / Q000138:chemical synthesis* / Q000494:pharmacology; D011985:Receptors, Serotonin / Q000378:metabolism; D012702:Serotonin Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D004146:Dioxanes; D010880:Piperidines; D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; C084858:SB 204070A; D008787:Metoclopramide