title: Isolation of Actinomyces species and Eikenella corrodens from patients with chronic diffuse sclerosing osteomyelitis.
abstract: Cultures from 26 patients with chronic diffuse sclerosing osteomyelitis of the mandible were studied. In most cases there was a mutualistic infection involving any one of the known human Actinomyces species together with Eikenella corrodens. In a few cases, Arachnia species were substituted for Actinomyces and gram-negative anaerobes for E corrodens. The specific culture protocol used to identify these organisms from clinical specimens is described. Taxonomic and experimental evidence that supports an infectious etiology are presented.
authors.affiliation: Division of Oral and Maxillofacial Surgery, University of Miami School of Medicine 33114.
authors.forename: R E
authors.initials: RE
authors.lastname: Marx
authors.forename: E R
authors.initials: ER
authors.lastname: Carlson
authors.forename: B R
authors.initials: BR
authors.lastname: Smith
authors.forename: N
authors.initials: N
authors.lastname: Toraya
mesh_terms: D000190:Actinomyces / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity; D000293:Adolescent; D000328:Adult; D001426:Bacterial Proteins; D002908:Chronic Disease; D004796:Clinical Enzyme Tests; D016124:Eikenella corrodens / Q000302:isolation & purification* / Q000472:pathogenicity; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000382:microbiology*; D008875:Middle Aged; D010019:Osteomyelitis / Q000382:microbiology* / Q000473:pathology; D015163:Superinfection; D009626:Terminology as Topic
chemical_list: D001426:Bacterial Proteins