title: Synthetic enhancement in gene interaction: a genetic tool come of age.
abstract: Synthetic enhancement, in which one mutation exacerbates the severity of another, is a genetic interaction of increasing importance in biology. This review focuses on the logic of interpreting synthetic enhancement, and begins by comparing the phenomenon with genetic suppression.
authors.affiliation: Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
authors.forename: L
authors.initials: L
authors.lastname: Guarente
mesh_terms: D000818:Animals; D009154:Mutation; D013489:Suppression, Genetic