title: Factors influencing survival in advanced gastric cancer.
abstract: Even though the incidence of gastric carcinoma is decreasing, the prognosis remains poor. A review of 88 patients with advanced gastric cancer was evaluated by univariate and multivariate analysis to determine prognostic factors. Univariate analysis showed that both "curative" resection (P = 0.006) and adjuvant chemotherapy (P = 0.02) were important therapy variables. These factors were not independent when evaluated by multivariate analysis. However, when they were combined and re-evaluated by multivariate analysis, the combination of "curative" surgery and adjuvant chemotherapy significantly improved survival in advanced gastric cancer (P = 0.04).
authors.affiliation: Dept. of Surgery, Loma Linda University Medical Center, CA 92354.
authors.forename: A D
authors.initials: AD
authors.lastname: Tabuenca
authors.forename: D R
authors.initials: DR
authors.lastname: Aitken
authors.forename: J K
authors.initials: JK
authors.lastname: Ihde
authors.forename: J
authors.initials: J
authors.lastname: Smith
authors.forename: C
authors.initials: C
authors.lastname: Garberoglio
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D015996:Survival Rate