title: Family study of obsessive-compulsive disorder in a Mexican population.
abstract: Twenty seven obsessive-compulsive disorder (OCD) patients were studied at the Instituto Mexicano de Psiquiatría in Mexico City. This is the first sample of OCD patients studied in Latin America. There was a significant sex ratio difference and a significant difference in the type of obsessions and compulsions displayed by males and females. Co-morbidity data demonstrated a high frequency of obsessive-compulsive personality disorders, depression, sexual abuse, suicidal attempts and neurological damage. Approximately one third of OCD cases demonstrated a positive family history. There was a higher than expected frequency of first degree relatives affected with OCD. In addition, this study may support the hypothesis that OCD and tics are genetically related.
authors.affiliation: Unidad de Genética Molecular Psiquiátrica PUIS-UNAM, Instituto Mexicano de Psiquiatría, D.F.
authors.forename: H
authors.initials: H
authors.lastname: Nicolini
authors.forename: K
authors.initials: K
authors.lastname: Weissbecker
authors.forename: J M
authors.initials: JM
authors.lastname: Mejía
authors.forename: M
authors.initials: M
authors.lastname: Sánchez de Carmona
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000235:genetics; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology / Q000235:genetics*; D012737:Sex Factors; D013981:Tic Disorders / Q000235:genetics