title: Aliphatic 1,2-alkanolamines--inhibitors of beta-glucanase from Candida utilis.
abstract: Aliphatic 1,2-alkanolamines inhibited beta-glucanase from Candida utilis. The highest inhibitory effect was observed with 1-dodecylamino-3-chloro-2-propanol (Ki = 1.0 mumol/L) and it was much higher than that of D-glucono-delta-lactone. Simple 1,2-alkanolamines, like 2-aminoethanol or 2-methylaminoethanol, did not exhibit any significant inhibitory effect.
authors.affiliation: Institute of Chemistry, Slovak Academy of Sciences, Bratislava.
authors.forename: B
authors.initials: B
authors.lastname: Steiner
authors.forename: J
authors.initials: J
authors.lastname: Omelková
authors.forename: B
authors.initials: B
authors.lastname: Proksa
authors.forename: V
authors.initials: V
authors.lastname: Sasinková
authors.forename: M
authors.initials: M
authors.lastname: Koós
mesh_terms: D000605:Amino Alcohols / Q000494:pharmacology*; D002175:Candida / Q000201:enzymology*; D005960:Glucosides / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors*
chemical_list: D000605:Amino Alcohols; D005960:Glucosides; C025193:4-nitrophenyl beta-D-glucoside; D006026:Glycoside Hydrolases