title: Mechanisms of illegitimate recombination.
abstract: Illegitimate recombination, which is one of the major causes of genome rearrangements, can occur in a number of ways. These might involve enzymes which cut and join DNA or enzymes which replicate DNA, as illustrated by two examples: (i) formation of deletions at the replication origin (ori) of an Escherichia coli bacteriophage, M13; and (ii) excision of E. coli transposon Tn10. It is proposed that a common theme to various ways by which illegitimate recombination can occur might be the capacity to create ends in the DNA molecule and to make the ends meet.
authors.affiliation: Laboratoire de Génétique Microbienne, Institut National de la Recherche Agronomique, Jouy en Josas, France.
authors.forename: S D
authors.initials: SD
authors.lastname: Ehrlich
authors.forename: H
authors.initials: H
authors.lastname: Bierne
authors.forename: E
authors.initials: E
authors.lastname: d'Alençon
authors.forename: D
authors.initials: D
authors.lastname: Vilette
authors.forename: M
authors.initials: M
authors.lastname: Petranovic
authors.forename: P
authors.initials: P
authors.lastname: Noirot
authors.forename: B
authors.initials: B
authors.lastname: Michel
mesh_terms: D017104:Bacteriophage M13 / Q000235:genetics; D004251:DNA Transposable Elements; D004926:Escherichia coli / Q000235:genetics; D011995:Recombination, Genetic
chemical_list: D004251:DNA Transposable Elements