title: Cardiopulmonary performance at rest and exercise after repair of total anomalous pulmonary venous connection.
abstract: Although long-term evaluations of patients after repair of total anomalous pulmonary venous connection have generally shown them to be clinically asymptomatic, assessment of their cardiovascular and pulmonary systems have been limited. Residual cardiopulmonary abnormalities undetected at rest may result in impaired function during exercise. To evaluate this hypothesis 9 patients underwent exercise testing after repair of total anomalous pulmonary venous connection. Pulmonary function testing was performed before exercise. Patients exercised using a 1-minute incremental bicycle or treadmill protocol monitoring heart rate, oxygen consumption, carbon dioxide production and minute ventilation. Compared with healthy children, the study patients had reduced maximal oxygen consumption and reduced oxygen consumption at ventilatory anaerobic threshold. Chronotropic response was impaired in 5 patients. Resting pulmonary functions showed evidence of mild restrictive lung disease. Breathing reserve was within normal limits. It is concluded that (1) aerobic capacity is mildly reduced after repair of total anomalous pulmonary venous connection, (2) chronotropic impairment is a common occurrence, and (3) pulmonary testing suggests mild restrictive lung disease that does not compromise exercise performance.
authors.affiliation: Cardiology Division, Children's Hospital of Michigan, Detroit 48201.
authors.forename: S M
authors.initials: SM
authors.lastname: Paridon
authors.forename: N M
authors.initials: NM
authors.lastname: Sullivan
authors.forename: J
authors.initials: J
authors.lastname: Schneider
authors.forename: W W
authors.initials: WW
authors.lastname: Pinsky
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005080:Exercise Test; D006330:Heart Defects, Congenital / Q000378:metabolism / Q000503:physiopathology* / Q000601:surgery; D006334:Heart Function Tests; D006439:Hemodynamics; D006801:Humans; D010101:Oxygen Consumption; D011667:Pulmonary Veins / Q000002:abnormalities* / Q000503:physiopathology / Q000601:surgery; D012119:Respiration; D012129:Respiratory Function Tests; D012146:Rest