title: [Changes in right ventricular hemodynamic function by unilateral pulmonary arterial occlusion test].
abstract: We performed unilateral pulmonary arterial occlusion test (UPAO) for the preoperative evaluation of lung function in patients undergoing lung resection. In this test, the main pulmonary artery of either side is occluded to simulate postoperative functional status. In order to evaluate the right ventricular hemodynamic function, we measured right ventricular ejection fraction (RVEF) and right ventricular end-diastolic volume index (RVEDVI) throughout UPAO by thermodilution method. We investigated the relationships between changes in right ventricular hemodynamic function and postoperative complications related to cardiac functions, namely arrhythmias or heart failure. Thirty-four patients without heart disease prior to lung resection were examined by UPAO, and RVEF and RVEDVI were measured. Analyses demonstrated that changes in RVEF were inversely correlated with changes in RVEDVI. In 6 cases, RVEDVI increased from control by over 20% during UPAO. All of these patients had postoperative cardiac complications. The hypothetical ventricular function curves showed a large increase in RVEDVI relative to right ventricular stroke work index (RVSWI), suggesting a decrease in right ventricular function. In conclusion, these results suggest that changes in RVEDVI during UPAO may predict postoperative cardiac complications in patients undergoing pulmonary resection.
authors.affiliation: Department of Surgery, Tohoku University, Sendai, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ueda
authors.forename: T
authors.initials: T
authors.lastname: Tanita
authors.forename: Y
authors.initials: Y
authors.lastname: Hoshikawa
authors.forename: T
authors.initials: T
authors.lastname: Nishimura
authors.forename: J
authors.initials: J
authors.lastname: Shibuya
authors.forename: S
authors.initials: S
authors.lastname: Iwabuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Asino
authors.forename: S
authors.initials: S
authors.lastname: Ono
authors.forename: K
authors.initials: K
authors.lastname: Koike
authors.forename: S
authors.initials: S
authors.lastname: Fujimura
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D011237:Predictive Value of Tests; D011651:Pulmonary Artery / Q000503:physiopathology*; D012129:Respiratory Function Tests / Q000379:methods; D014655:Vascular Resistance; D016278:Ventricular Function, Right