title: Syndrome X.
abstract: Using cross-sectional and longitudinal analysis of data from the San Antonio Heart Study, syndrome X (primary insulin resistance syndrome) has been redefined in terms of hyperinsulinaemia combined with changes in glucose tolerance, lipid pattern, blood pressure and body fat distribution. Syndrome X is itself an atherogenic cardiovascular risk factor, which interacts with environmental and genetic factors to lead to the eventual development of the endpoint of cardiovascular disease.
authors.affiliation: CNR Institute of Clinical Physiology, University of Pisa, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Ferrannini
mesh_terms: D000273:Adipose Tissue; D001823:Body Composition; D002318:Cardiovascular Diseases / Q000209:etiology; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood; D012307:Risk Factors; D013577:Syndrome
chemical_list: D007328:Insulin; D008055:Lipids