SOS mutagenesis.
In Escherichia coli, UV and many chemicals appear to cause mutagenesis by a process of translesion synthesis that requires some form of DNA polymerase III and the SOS-regulated proteins UmuD, UmuC and RecA. An analysis of SOS mutagenesis offers insights into the molecular basis of induced mutagenesis and into mechanisms of DNA damage tolerance.
Murli
S
S
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
Walker
G C
GC
D004249:DNA Damage; D004926:Escherichia coli / Q000235:genetics*; D016296:Mutagenesis; D013014:SOS Response, Genetics / Q000235:genetics*