[A difference in the growth-controlling action of Syrian hamster fibroblasts from early and late embryogenesis on tumor cells with different degrees of malignancy].
The difference in the effect of embryo fibroblasts from early (EHEF) and late (LHEF) embryos on the proliferative activity (PA) of transformed and tumour cells of different degree of malignancy was demonstrated in culture. The dense monolayer of EHEF cells exerted stronger growth-inhibitory influence on the PA of all tested strains of the transformed and tumour cells as compared to the LHEF cells.
Gurova
E V
EV
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects / Q000473:pathology; D002478:Cells, Cultured / Q000166:cytology / Q000187:drug effects / Q000502:physiology; D006224:Cricetinae; D005314:Embryonic and Fetal Development / Q000502:physiology*; D005347:Fibroblasts / Q000166:cytology / Q000502:physiology; D005865:Gestational Age; D006131:Growth Inhibitors / Q000494:pharmacology*; D008647:Mesocricetus; D009374:Neoplasms, Experimental / Q000473:pathology*; D013997:Time Factors; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000473:pathology
D006131:Growth Inhibitors
Razlichie v rostkontroliruiushchem deĭstvii fibroblastov siriĭskogo khomiaka rannikh i pozdnikh srokov émbriogeneza na opukholevye kletki razlichnoĭ stepeni zlokachestvennosti.