title: [Screening of microalbuminuria with the Micral-Test. A semi-quantitative urinary dipstick].
abstract: Microalbuminuria, defined as a urinary albumin excretion rate of 20-200 micrograms/min, predicts diabetic nephropathy and cardiovascular disease in diabetic patients. An increased urinary albumin excretion rate is probably also associated with cardiovascular disease in non-diabetic subjects. Thus, screening for microalbuminuria is of major importance. A semi-quantitative urinary dipstick method, Micral-Test, has been developed for this purpose. In a urine sample collected overnight from each of 1359 subjects the Micral-Test was evaluated with a quantitative ELISA-method as the standard. Sensitivity, specificity and diagnostic specificity in detecting microalbuminuria was 92, 58 and 12% respectively. The prevalence of microalbuminuria was 5.6%. In conclusion, the Micral-Test is highly sensitive in detecting microalbuminuria, but at the expense of a relatively high number of false positive tests.
authors.affiliation: Steno Diabetes Center, Gentofte.
authors.forename: J S
authors.initials: JS
authors.lastname: Jensen
authors.forename: K
authors.initials: K
authors.lastname: Borch-Johnsen
authors.forename: B F
authors.initials: BF
authors.lastname: Feldt-Rasmussen
authors.forename: G
authors.initials: G
authors.lastname: Jensen
mesh_terms: D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D003430:Cross-Sectional Studies; D003718:Denmark / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D015995:Prevalence; D011934:Reagent Strips
chemical_list: D011934:Reagent Strips
vernacular_title: Screening for mikroalbuminuri med Micral-Test. En semikvantitativ urinstix.