ACTH induced adrenal enlargement in infants treated for infantile spasms and acute cerebellar encephalopathy.
ACTH is used in childhood to treat infantile spasms and acute cerebellar encephalopathy (opsoclonus-cerebellar ataxia syndrome). We report two infants with ultrasonographic and CT evidence of massive, reversible adrenal enlargement secondary to exogenous ACTH therapy for these disorders.
Liebling
M S
MS
Department of Radiology, Babies Hospital, New York, NY 10032.
Starc
T J
TJ
McAlister
W H
WH
Ruzal-Shapiro
C B
CB
Abramson
S J
SJ
Berdon
W E
WE
D000208:Acute Disease; D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology*; D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage / Q000009:adverse effects*; D002526:Cerebellar Diseases / Q000188:drug therapy*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000139:chemically induced / Q000000981:diagnostic imaging; D007223:Infant; D008297:Male; D013036:Spasms, Infantile / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D000324:Adrenocorticotropic Hormone