title: [Pulmonary carcinoma associated with bullous emphysema].
abstract: Malignant complication of pulmonary bullous disease is rare but not negligible. Its importance lies in the young age when it appears. Eighty-nine cases in the literature, including four of our own cases, are included in this review. Etiopathogenic theories are discussed along with clinical, radiological, pathological, diagnostic, prognostic, and treatment characteristics. Smoking is a primary factor in this process, and quitting is key in terms of prevention. Surgical methods are usually necessary to perform the diagnosis, but that does not exclude the use of other techniques-particularly, fine-needle aspiration biopsy under radiological control-whose role should be validated. The prognosis is bad if there is no commitment to prevention. Even though the value of serial radiological controls is unknown, such controls may help in the early detection of neoplastic degeneration in bullous disease. The nature of the problem in handling these cases therapeutically is determined by the severity of bullous dystrophy: therefore, surgery should be considered on an individual basis.
authors.affiliation: Sección de Neumología, Hospital General Yagüe, Burgos.
authors.forename: J F
authors.initials: JF
authors.lastname: Pascual Lledó
authors.forename: J
authors.initials: J
authors.lastname: Terán Santos
authors.forename: J P
authors.initials: JP
authors.lastname: García Muñoz
authors.forename: L
authors.initials: L
authors.lastname: Rodríguez Pascual
authors.forename: F
authors.initials: F
authors.lastname: Gallo Marín
authors.forename: C
authors.initials: C
authors.lastname: de Abajo Cucurrull
authors.forename: A
authors.initials: A
authors.lastname: Pueyo Bastida
authors.forename: J L
authors.initials: JL
authors.lastname: Viejo Bañuelos
mesh_terms: D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy
vernacular_title: Carcinoma pulmonar asociado a enfisema bulloso.