Risk factors for atherosclerotic aortoiliac occlusive disease.
Notwithstanding the difficulties in analysis because of the small number of studies available, patients with aortoiliac atherosclerosis, irrespective of their sex, have a particular "risk profile" that includes tobacco use, young age, diabetes (rare), frequent hypercholesterolemia, and limited atheroma. It must be remembered, however, that most studies have not dealt with the specific risk factors of lower limb arterial disease and the location of disease in the aortoiliac vessels. It is possible that the classical analysis of the vascular risk factors has overlooked one or more major factors such as hyperhomocysteinemia. This underscores the necessity to conduct further prospective studies specifically focused on the various aspects of lower limb and aortoiliac arterial disease in particular.
Cacoub
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Service de Médecine Interne, CHU Pitié-Salpétrière, Paris, France.
Godeau
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P
D001018:Aortic Diseases / Q000209:etiology*; D001161:Arteriosclerosis / Q000209:etiology*; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006951:Hyperlipoproteinemias / Q000150:complications; D007083:Iliac Artery / Q000473:pathology*; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects