Effects of dietary intakes on plasma lipids, lipoproteins, and apolipoproteins in free-living elderly men and women.
Plasma lipid and apolipoprotein (apo) A-I and B concentrations and habitual dietary intakes were determined in 306 free-living elderly individuals (119 men and 187 women, age range 60-100 y). Plasma lipid and apo A-I concentrations were significantly higher in women than in men. In older men, plasma triglyceride, total cholesterol, and apo B concentrations were significantly lower than in younger men, whereas a significant trend towards lower LDL-cholesterol concentrations was observed in older women. Energy intake and percent macronutrient intake were not influenced by age. Higher carbohydrate intake was associated with lower HDL cholesterol and apo A-I concentrations, whereas higher total fat intake was associated with higher apo A-I concentrations. Higher vitamin A intake was associated with higher plasma concentrations of HDL cholesterol and apo A-I. Our data indicate that both dietary and plasma concentrations of vitamin A, body mass index, age, and sex are important determinants of plasma lipid concentrations in the elderly.
Lamon-Fava
S
S
Lipid Metabolism Laboratory, Tufts University, Boston, MA 02111.
Jenner
J L
JL
Jacques
P F
PF
Schaefer
E J
EJ
D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001053:Apolipoproteins / Q000032:analysis*; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000097:blood; D015992:Body Mass Index; D001835:Body Weight; D003327:Coronary Disease / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood; D004032:Diet; D004034:Diet Surveys; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014801:Vitamin A / Q000008:administration & dosage / Q000097:blood
D001053:Apolipoproteins; D008055:Lipids; D008074:Lipoproteins; D014801:Vitamin A; D001205:Ascorbic Acid