A syndrome of acute interstitial nephritis and anterior uveitis.
A syndrome of acute interstitial nephritis (AIN) and anterior uveitis is described in two children and the literature is reviewed. These disorders appear to improve, in uncontrolled studies, with systemic and topical ophthalmic corticosteroid treatment. Although the renal and ocular prognoses appear good, it is important to recognize that patients with AIN are at risk for uveitis and if present, consultation with an ophthalmologist is recommended.
Bunchman
T E
TE
Division of Pediatric Nephrology, University of Michigan, Ann Arbor.
Bloom
J N
JN
D000208:Acute Disease; D000287:Administration, Topical; D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013577:Syndrome; D014606:Uveitis, Anterior / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids