Uraemia with concomitant urothelial cancer.
We report our experience with 3 uraemic patients who were found to have transitional cell carcinoma of the renal pelvis, ureter and urinary bladder after undergoing haemodialysis for an average of 18 months (range 11-28). The underlying causes of renal failure were chronic glomerulonephritis or pyelonephritis. Bloody urethral discharge was the cardinal symptom. Because of anuria, it was often discovered at a late stage. In spite of their poor general condition and advanced stage, palliative surgical intervention was still performed. After a mean follow-up of 9 months, progression of disease was noted in 1 patient. The importance of regular follow-up in patients with end-stage renal disease for early detection of concomitant cancer cannot be over-emphasised. Uraemic patients with urothelial cancer should be treated in the same way as non-uraemic patients, since aggressive surgical intervention may improve their quality of life and prolong their survival.
Jiaan
B P
BP
Department of Surgery, Veterans General Hospital Kaohsiung, Taiwan, Republic of China.
Yu
C C
CC
Lee
Y H
YH
Huang
J K
JK
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000150:complications* / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D007680:Kidney Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014511:Uremia / Q000150:complications*; D014516:Ureteral Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D014567:Urography