Reactivation in children of juvenile chronic arthritis and chronic iridocyclitis associated with human herpesvirus-6 infection.
The human herpesvirus-6 (HHV-6) causes exanthem subitum. Moreover it can provoke a large scale of different other clinical symptoms. The life-long persistence of human herpes viruses is well known (HSV 1 and 2, VZV, CMV, EBV). For the HHV-6 we have described here for the first time the onset/reactivation of juvenile chronic arthritis (jcA) and chronic iridocyclitis as chronically active and persistent infection in two children of school age.
Wiersbitzky
S
S
Department of Pediatrics, Ernst-Moritz-Arndt-University, Greifswald, Germany.
Ratzmann
G W
GW
Bruns
R
R
Wiersbitzky
H
H
D000914:Antibodies, Viral / Q000032:analysis; D001171:Arthritis, Juvenile / Q000276:immunology*; D002648:Child; D005077:Exanthema Subitum / Q000276:immunology*; D005260:Female; D015654:Herpesvirus 6, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D015863:Iridocyclitis / Q000276:immunology*; D008297:Male; D012008:Recurrence
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M