Isolation of Actinomyces species and Eikenella corrodens from patients with chronic diffuse sclerosing osteomyelitis.
Cultures from 26 patients with chronic diffuse sclerosing osteomyelitis of the mandible were studied. In most cases there was a mutualistic infection involving any one of the known human Actinomyces species together with Eikenella corrodens. In a few cases, Arachnia species were substituted for Actinomyces and gram-negative anaerobes for E corrodens. The specific culture protocol used to identify these organisms from clinical specimens is described. Taxonomic and experimental evidence that supports an infectious etiology are presented.
Marx
R E
RE
Division of Oral and Maxillofacial Surgery, University of Miami School of Medicine 33114.
Carlson
E R
ER
Smith
B R
BR
Toraya
N
N
D000190:Actinomyces / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity; D000293:Adolescent; D000328:Adult; D001426:Bacterial Proteins; D002908:Chronic Disease; D004796:Clinical Enzyme Tests; D016124:Eikenella corrodens / Q000302:isolation & purification* / Q000472:pathogenicity; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000382:microbiology*; D008875:Middle Aged; D010019:Osteomyelitis / Q000382:microbiology* / Q000473:pathology; D015163:Superinfection; D009626:Terminology as Topic
D001426:Bacterial Proteins