CGRP-immunoreactive cells supplying laryngeal sensory nerve fibres in the cat's nodose ganglion.
Through a combination of retrograde staining by wheat germ agglutinin (WGA) and immunohistochemistry, calcitonin gene-related peptide (CGRP)-reactive sensory neurons projecting from the laryngeal mucosa were detected in the feline nodose ganglion. The size of the CGRP-immunoreactive cell which was regarded as a laryngeal sensory neuron, was about 60 microns in diameter: the shape of the immunoreactive laryngeal sensory neuron was unipolar. CGRP-reacted laryngeal sensory cells were found in the rostral part of the nodose ganglion extending to the middle part. They aggregated in the most rostral part, were sparse in other parts and were approximately 50 per cent of WGA-reactive laryngeal sensory neurons in number. Our results suggest that this neurotransmitter might play an important role in laryngeal peripheral sensory innervation.
Tanaka
Y
Y
Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Kurume University, Japan.
Yoshida
Y
Y
Hirano
M
M
D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000032:analysis*; D002415:Cats; D005260:Female; D007150:Immunohistochemistry; D007823:Laryngeal Nerves / Q000737:chemistry*; D008297:Male; D009475:Neurons, Afferent / Q000737:chemistry*; D009620:Nodose Ganglion / Q000737:chemistry* / Q000166:cytology; D014909:Wheat Germ Agglutinins
D014909:Wheat Germ Agglutinins; D015740:Calcitonin Gene-Related Peptide