title: [Post sinusoidal obstruction of the hepatic venous flow associated with antiphospholipid syndrome in 3 cases].
abstract: Three cases of post-sinusoidal hepatic blood flow obstruction as the main feature of antiphospholipid syndrome are reported. Clinically, these patients developed jaundice, malaise, ascites and hepatomegaly. Ultrasonography-Doppler and hepatic venography showed small hepatic vein disease in two and partial occlusion in the suprahepatic segment of inferior vena cava in the remaining patient. In all, anticardiolipin antibodies were positive and activated partial thromboplastin time was prolonged. This experience emphasizes that in patients with post sinusoidal portal hypertension, a systematic search for antiphospholipid syndrome must be carried out.
authors.affiliation: Departamento de Medicina, Universidad de Chile, Santiago de Chile.
authors.forename: M
authors.initials: M
authors.lastname: Velasco
authors.forename: J
authors.initials: J
authors.lastname: Chesta
authors.forename: M
authors.initials: M
authors.lastname: Grisanti
authors.forename: G
authors.initials: G
authors.lastname: Smok
authors.forename: J
authors.initials: J
authors.lastname: Poniachik
authors.forename: J
authors.initials: J
authors.lastname: Brahm
authors.forename: R
authors.initials: R
authors.lastname: Alvarez
authors.forename: M
authors.initials: M
authors.lastname: Fernández
authors.forename: J C
authors.initials: JC
authors.lastname: Seitz
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D006502:Budd-Chiari Syndrome / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male
vernacular_title: Obstrucción postsinusoidal del flujo venoso hepático asociado a síndrome antifosfolípido en 3 casos.