Cyclosporine-induced nephrotoxicity in the rat. The effect of alpha 1-adrenoceptor blockade with prazosin.
Penner
S B
SB
Department of Internal Medicine, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.
Jeffery
J J
JJ
Smyth
D D
DD
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D016572:Cyclosporine / Q000494:pharmacology / Q000633:toxicity*; D007668:Kidney / Q000187:drug effects* / Q000294:innervation / Q000502:physiology; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D011224:Prazosin / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D018340:Receptors, Adrenergic, alpha-1 / Q000187:drug effects* / Q000502:physiology; D012964:Sodium / Q000097:blood / Q000652:urine; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000502:physiology; D014508:Urea / Q000097:blood
D018340:Receptors, Adrenergic, alpha-1; D016572:Cyclosporine; D014508:Urea; D012964:Sodium; D011224:Prazosin