title: The effect of aspirin, paracetamol and analgin on pharmacokinetics of chloroquine.
abstract: The effect of Aspirin, paracetamol and analgin on the kinetic profile of a single oral dose of chloroquine was studied in 8 healthy subjects. Aspirin did not alter the kinetic parameters of chloroquine whereas paracetamol and analgin significantly enhanced the Cmax and AUC0-alpha of chloroquine (P < 0.01, < 0.05 respectively).
authors.affiliation: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Tawi.
authors.forename: R K
authors.initials: RK
authors.lastname: Raina
authors.forename: G
authors.initials: G
authors.lastname: Bano
authors.forename: V
authors.initials: V
authors.lastname: Amla
authors.forename: V
authors.initials: V
authors.lastname: Kapoor
authors.forename: K L
authors.initials: KL
authors.lastname: Gupta
mesh_terms: D000082:Acetaminophen / Q000494:pharmacology*; D000328:Adult; D001241:Aspirin / Q000494:pharmacology*; D002738:Chloroquine / Q000097:blood / Q000493:pharmacokinetics*; D004177:Dipyrone / Q000494:pharmacology*; D004347:Drug Interactions; D006801:Humans; D008297:Male; D008954:Models, Biological
chemical_list: D000082:Acetaminophen; D004177:Dipyrone; D002738:Chloroquine; D001241:Aspirin