Cervical conization and preterm delivery/low birth weight. A systematic review of the literature.
OBJECTIVE
Evaluate the effect of cervical conization on preterm birth/low birth weight (LBW).


METHODS
A systematic review of the literature using external or internal controls.


RESULTS
The typical odds ratio for preterm delivery in women with prior cervical conization using external controls was 3.23 (95% confidence interval 2.29-4.55). Using internal controls the typical odds ratio for LBW was 2.97 (95% confidence interval 1.09-8.05). Using external controls the typical odds ratio for LBW was 2.31 (95% confidence interval 1.33-3.99).


CONCLUSIONS
Women with cervical conization are at higher risk for preterm birth than external controls, and the surgical intervention as such is a major determining factor.
Kristensen
J
J
Department of Obstetrics and Gynecology, University Hospital (Rigshospitalet), Copenhagen, Denmark.
Langhoff-Roos
J
J
Wittrup
M
M
Bock
J E
JE
D002584:Cervix Uteri / Q000601:surgery*; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000209:etiology*; D016017:Odds Ratio; D011247:Pregnancy; D012307:Risk Factors