The determination of diethylstilbestrol (DES) in the faeces and tissues of chickens treated with DES and in the faeces and tissue samples of calves, lambs and chickens collected from various areas of Turkey.
Diethylstilbestrol (DES) analyses were carried out on muscle, liver, kidney and faeces samples of 20 control and 20 experimental broilers to which 5 mg DES/day had been given orally for a period of 7 days. The treated samples were analysed using the Radioimmunoassay method. The removal time of DES from the tissues was determined. Five days following the final administration of DES, its faecal concentration was 151 ppb. However, 7 days after the final administration faecal DES concentrations increased again. On the first day after the final DES administration, DES concentrations in the liver, muscle and kidney were 0.78, 0.74 and 1.33 ppb, respectively. While these values measured on the final day were within the range of the control values. There was an increase of DES in plasma at the end of the experimental period. A total of 1811 muscle, liver, kidney and faeces samples of calves, lambs and chickens and feed samples collected from various areas in Turkey were analysed for the presence of DES. Positive samples for chicken feed was 36.9%. Also 1.9% of the chicken faeces samples were DES positive. All other samples were negative for DES.
Ersoy
E
E
Biochemistry Department, Veterinary Faculty, Ankara University.
Agthe
O
O
Ergun
H
H
Sel
T
T
Güldür
T
T
D000818:Animals; D002417:Cattle / Q000378:metabolism*; D002645:Chickens / Q000378:metabolism*; D004054:Diethylstilbestrol / Q000032:analysis*; D004350:Drug Residues / Q000032:analysis*; D005243:Feces / Q000737:chemistry; D012756:Sheep / Q000378:metabolism*; D014421:Turkey
D004054:Diethylstilbestrol