title: A cytotoxic beta-carboline from the bryozoan Catenicella cribraria.
abstract: 1-Vinyl-8-hydroxy-beta-carboline was identified as the cytotoxic constituent of the bryozoans Catenicella cribraria and Cribricellina cribraria. Literature nmr data for this previously known compound, now reported from a new source, were corrected.
authors.affiliation: Laboratory of Drug Discovery Research & Development, National Cancer Institute, Frederick, Maryland 21702-1201.
authors.forename: J A
authors.initials: JA
authors.lastname: Beutler
authors.forename: J H
authors.initials: JH
authors.lastname: Cardellina
authors.forename: T
authors.initials: T
authors.lastname: Prather
authors.forename: R H
authors.initials: RH
authors.lastname: Shoemaker
authors.forename: M R
authors.initials: MR
authors.lastname: Boyd
authors.forename: K M
authors.initials: KM
authors.lastname: Snader
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002013:Bryozoa / Q000737:chemistry*; D002243:Carbolines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002855:Chromatography, Thin Layer; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D014753:Vinyl Compounds / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D002243:Carbolines; D014753:Vinyl Compounds; C085149:1-vinyl-8-hydroxy-beta-carboline