Differential pulse voltammetric determination of 7-hydroxycoumarin in human urine.
The electrochemical behaviour of 7-OH-coumarin at the bare glassy carbon electrode has been studied using differential pulse voltammetry, and based on anodic detection of this metabolite at 0.66 V (vs SCE) using DC amperometry, a method has been developed for the determination of 7-OH-coumarin levels in urine samples, and a pharmacokinetic profile established.
Dempsey
E
E
School of Chemical Sciences, Dublin City University, Republic of Ireland.
O'Sullivan
C
C
Smyth
M R
MR
Egan
D
D
O'Kennedy
R
R
Wang
J
J
D004566:Electrodes; D006801:Humans; D014468:Umbelliferones / Q000652:urine*
D014468:Umbelliferones; C031477:7-hydroxycoumarin