title: Maxon is an optimal suture for bile duct anastomoses in pigs.
abstract: BACKGROUND
  Three commonly used sutures were tested in a pig model of bile duct anastomosis to assess their relative contributions to inflammation and scarring.
  
  
  METHODS
  Thirty pigs were randomised to bile duct division and anastomosis with either polyglyconate (Maxon), polyglactin 910 (Vicryl) or polypropylene (Prolene). Half the animals were sacrificed at two weeks and the remainder at 23 weeks. Anastomoses were assessed by cholangiography, scanning electron microscopy and light microscopy.
  
  
  RESULTS
  There was less short term histological reaction with the two monofilament materials, Prolene and Maxon, compared to the braided suture Vicryl. Maxon was associated with less long term inflammation than Prolene, was found to handle better, and has an advantage over Prolene by being absorbable.
  
  
  CONCLUSIONS
  Maxon is an optimal suture for bile duct anastomoses. Its long term absorption characteristics make it suitable for situations where bile duct healing may be delayed.
authors.affiliation: Department of Surgery, Flinders University, Adelaide, South Australia.
authors.forename: P
authors.initials: P
authors.lastname: Jeans
authors.forename: P
authors.initials: P
authors.lastname: Hall
authors.forename: Y F
authors.initials: YF
authors.lastname: Liu
authors.forename: R A
authors.initials: RA
authors.lastname: Baker
authors.forename: A
authors.initials: A
authors.lastname: Holt
authors.forename: G T
authors.initials: GT
authors.lastname: Saccone
authors.forename: J R
authors.initials: JR
authors.lastname: Harvey
authors.forename: J
authors.initials: J
authors.lastname: Scicchitano
authors.forename: J
authors.initials: J
authors.lastname: Toouli
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001652:Bile Ducts / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D002758:Cholangiography; D005260:Female; D008297:Male; D008855:Microscopy, Electron, Scanning; D008954:Models, Biological; D011098:Polyglactin 910; D011108:Polymers; D011126:Polypropylenes; D011183:Postoperative Complications / Q000401:mortality*; D011897:Random Allocation; D015996:Survival Rate; D013537:Sutures; D013552:Swine; D013997:Time Factors; D014945:Wound Healing
chemical_list: D011108:Polymers; D011126:Polypropylenes; D011098:Polyglactin 910; C046409:polyglyconate