title: [A case of pulmonary lymphangiomyomatosis treated with bilateral oophorectomy and methyl-progesterone-acetate].
abstract: A case of pulmonary lymphangiomyomatosis is reported. A 37-year-old woman was admitted with hemosputum and dyspnea on exertion. Chest roentgenogram revealed diffuse reticulonodular shadows and arterial hypoxemia was present. Pulmonary function tests showed severe restrictive & obstructive impairment, and pulmonary perfusion scintigraphy with 99mTc-MAA showed non-segmental disproportion. The histological diagnosis of pulmonary lymphangiomyomatosis was made by transbronchial lung biopsy. She underwent bilateral oophorectomy under general anesthesia. However, the arterial hypoxemia advanced gradually, and medroxyprogesterone-acetate (MPA) was commenced (200 mg/day). Her condition remained stable after the description of MPA.
authors.affiliation: Department of Chest Diseases & Thoracic Surgery, Kansai Denryoku Hospital, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Itoi
authors.forename: M
authors.initials: M
authors.lastname: Kuwabara
authors.forename: K
authors.initials: K
authors.lastname: Okubo
authors.forename: K
authors.initials: K
authors.lastname: Matsuoka
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000628:therapy*; D018192:Lymphangioleiomyomatosis / Q000628:therapy*; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage*; D010052:Ovariectomy
chemical_list: D017258:Medroxyprogesterone Acetate