Diffuse alveolar hemorrhage due to antibasement membrane antibody disease appearing with a polyglandular autoimmune syndrome.
We describe a patient with type 3-C polyglandular autoimmune syndrome who presented with diffuse alveolar hemorrhage and normal renal function. The diagnosis of antibasement membrane antibody disease was established by immunofluorescent staining of transbronchial biopsy specimens. We suggest the incorporation of antibasement membrane antibody disease into the spectrum of diseases that define the polyglandular autoimmune syndromes.
Moss
M
M
Division of Pulmonary Sciences and Critical Care Medicine, Denver General Hospital.
Neff
T A
TA
Colby
T V
TV
Schwarz
M I
MI
Zamora
M R
MR
D000328:Adult; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D001485:Basement Membrane / Q000276:immunology; D005260:Female; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008171:Lung Diseases / Q000209:etiology / Q000276:immunology; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications*; D011650:Pulmonary Alveoli / Q000276:immunology* / Q000473:pathology*
D000888:Antibodies, Anti-Idiotypic; D007074:Immunoglobulin G