title: Adult T-cell leukemia involving the central nervous system after remission of adult respiratory distress syndrome.
abstract: We report a rare case of adult T-cell leukemia (ATL) in which the patient had an acute type of ATL involving the central nervous system (CNS) after remission of adult respiratory distress syndrome (ARDS) due to human T lymphotropic virus type 1 associated bronchopneumopathy. A 62-year-old woman was admitted to the hospital because of ARDS. Pulse therapy with methylprednisolone improved ARDS, but she fell into a coma due to ATL and CNS invasion 5 months after recovery. Although chemotherapy decreased the fraction of abnormal lymphocytes, her consciousness level did not improve and she died.
authors.affiliation: First Department of Internal Medicine, Matsushita Memorial Hospital, Osaka, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Hara
authors.forename: K
authors.initials: K
authors.lastname: Yoshioka
authors.forename: A
authors.initials: A
authors.lastname: Hori
authors.forename: A
authors.initials: A
authors.lastname: Ohsawa
authors.forename: S
authors.initials: S
authors.lastname: Yokoo
mesh_terms: D016543:Central Nervous System Neoplasms / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications* / Q000175:diagnosis; D008168:Lung / Q000000981:diagnostic imaging; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography; D012128:Respiratory Distress Syndrome / Q000150:complications*