[A female case of isolated angiitis of the central nervous system].
Isolated angiitis of the central nervous system (IACNS) is an extremely rare disorder in childhood. This report presents an 8-year-old female case of IACNS. She showed paresis at the right face and upper limb at the onset, followed by various focal neurological symptoms. Cranial T2-weighted magnetic resonance imaging revealed multiple subcortical high signal lesions, which appeared and disappeared in accordance with her clinical manifestations. The level of her plasma thrombin-antithrombin III complex (TAT) was high during the active phase of the illness and seemed to be a useful marker for the detection of vasculitis in the CNS. Complete remission was achieved by the combination therapy of prednisone and cyclophosphamide.
Shimizu
N
N
Department of Pediatrics, School of Medicine, University of Chiba.
Sugita
K
K
Ishii
M
M
Kawazoe
Y
Y
Miyamoto
H
H
Niimi
H
H
D015901:Angiography, Digital Subtraction; D001927:Brain Diseases / Q000175:diagnosis* / Q000188:drug therapy; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011241:Prednisone / Q000627:therapeutic use; D012074:Remission Induction; D014657:Vasculitis / Q000175:diagnosis* / Q000188:drug therapy
D011241:Prednisone