Instructed polarisation of sister chromatids.
We discuss a mechanism leading to antipodal polarisation of sister chromatids. The information to migrate to opposite poles originates from the interaction between spindle microtubules and the kinetochores when two sister chromatids disentangle from each other at the centromeric braid.
Matioli
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GT
USC Medical School, Los Angeles 90033.
D002503:Centromere / Q000502:physiology / Q000648:ultrastructure; D002842:Chromatids / Q000502:physiology* / Q000648:ultrastructure; D008870:Microtubules / Q000502:physiology / Q000648:ultrastructure; D008938:Mitosis; D008954:Models, Biological; D009068:Movement; D008941:Spindle Apparatus / Q000502:physiology / Q000648:ultrastructure