[A case report of CMV hepatitis and nephropathy after living related renal transplantation].
Cytomegalovirus (CMV) infection is serious complication after clinical renal transplantation. A case of CMV hepatitis and nephropathy after living related renal transplantation was reported. A 32-year-old women with chronic renal failure due to systemic lupus erythematosis received a renal transplant from her mother. On day 35 after operation, she developed high fever with hepatic and renal damage and was diagnosed as CMV infection from clinical course and virological examination. Although the use of anti-CMV high titer gamma globulin with reduction of immunosuppressant therapy could not cure the infection, the administration of Ganciclovir improved hepatic and renal damage without deterioration of renal graft function.
Tanaka
S
S
Department of Surgery, National Okayama Hospital, Okayama, Japan.
Fujioka
M
M
Sasaki
S
S
D000328:Adult; D003586:Cytomegalovirus Infections / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006525:Hepatitis, Viral, Human / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D007674:Kidney Diseases / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*
D015774:Ganciclovir