title: Thermogenic response to food: intra-individual variability and measurement reliability.
abstract: The objective of this study was to assess the reliability and variability of the thermogenic response to food (TRF) in healthy adult subjects. Eight healthy adults (4 men, 4 women) participated in three sets of measurements of TRF, evaluated by indirect calorimetry with a ventilated hood system during 6 hours after a standardized meal. The reliability of TRF measurement was estimated using a one-way analysis of variance with repeated measurements. After the 6-hour period of measurement, the within-subject coefficient of variation for TRF was 10.7%, while the between-subject variability was twice as high (24.1%, p < 0.01). The overall reliability estimate of TRF was acceptable (RE > or = 0.80) after a single measurement which lasted at least 6 hours postprandially, while duplicate and triplicate measurements reached a similar degree of reliability in 3 hours. These results suggest that intra-individual variability contributes little to the variability commonly seen in TRF studies, provided that the measurement period is at least 6 hours.
authors.affiliation: Department of Nutrition, Faculty of Medicine, University of Montreal, Quebec, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Houde-Nadeau
authors.forename: L
authors.initials: L
authors.lastname: de Jonge
authors.forename: D R
authors.initials: DR
authors.lastname: Garrel
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000886:Anthropometry; D001481:Basal Metabolism; D001833:Body Temperature Regulation; D002153:Calorimetry, Indirect; D002245:Carbon Dioxide / Q000378:metabolism; D004435:Eating / Q000502:physiology*; D002149:Energy Intake; D004734:Energy Metabolism / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010101:Oxygen Consumption; D011659:Pulmonary Gas Exchange; D015203:Reproducibility of Results
chemical_list: D002245:Carbon Dioxide