[Membrane control of the photodeblocking reaction of cytochrome oxidase in the mitochondrial electron transport chain].
Hyperosmotic shrinkage and hypoosmotic swelling of the internal mitochondrial membrane decrease considerably the efficiency of the reaction of the cyanide photodissociation from the cytochrome oxidase. The osmotic effect increases after the reduction of the membrane potential by a protonophore uncoupler. This suggests that the local photochemical reaction is subject to membrane control.
Konev
S V
SV
Rudenok
A N
AN
Vybiranets
L M
LM
D000818:Animals; D004579:Electron Transport; D003576:Electron Transport Complex IV / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000528:radiation effects; D004789:Enzyme Activation; D007425:Intracellular Membranes / Q000201:enzymology* / Q000502:physiology; D008564:Membrane Potentials; D008930:Mitochondria, Liver / Q000201:enzymology* / Q000502:physiology; D008933:Mitochondrial Swelling; D010782:Photolysis; D011190:Potassium Cyanide / Q000494:pharmacology; D051381:Rats
D003576:Electron Transport Complex IV; D011190:Potassium Cyanide
Membrannyĭ kontrol' reaktsii fotodeblokirovaniia tsitokhromoksidazy v élektrontransportnoĭ tsepi mitokhondriĭ.