title: Photodistributed nifedipine-induced facial telangiectasia.
abstract: Five months after starting nifedipine (Adalat), two patients developed photodistributed facial telangiectasia, which became more noticeable with time. Neither patient complained of photosensitivity or flushing. Both patients reported a significant cosmetic improvement after discontinuing the drug. One commenced the closely related drug amlodipine 3 years later, with recurrence of telangiectasia. The photodistribution of the telangiectasia suggests a significant drug/light interaction.
authors.affiliation: Department of Dermatology, Ninewells Hospital and Medical School, Dundee, U.K.
authors.forename: P
authors.initials: P
authors.lastname: Collins
authors.forename: J
authors.initials: J
authors.lastname: Ferguson
mesh_terms: D000328:Adult; D017311:Amlodipine / Q000009:adverse effects; D005148:Facial Dermatoses / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000009:adverse effects*; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000473:pathology; D013684:Telangiectasis / Q000139:chemically induced* / Q000473:pathology
chemical_list: D017311:Amlodipine; D009543:Nifedipine