title: Severe idiopathic congenital aplastic anemia: role of hematopoietic growth factors.
abstract: A baby boy with constitutional aplastic anemia refractory to treatment with hematopoietic growth factors underwent BMT from an unrelated HLA-compatible donor. The BM failed to engraft but the combination of a conditioning regimen, immunosuppression and hematopoietic growth factors resulted in a recovery of the patient's own BM and a good outcome.
authors.affiliation: Department of Pediatrics, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Vermylen
authors.forename: G
authors.initials: G
authors.lastname: Cornu
authors.forename: M
authors.initials: M
authors.lastname: DeWitte
authors.forename: M T
authors.initials: MT
authors.lastname: Heremans
authors.forename: J
authors.initials: J
authors.lastname: Ninane
authors.forename: B
authors.initials: B
authors.lastname: Brichard
mesh_terms: D000015:Abnormalities, Multiple; D000741:Anemia, Aplastic / Q000151:congenital* / Q000601:surgery / Q000628:therapy; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D004351:Drug Resistance; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D006410:Hematopoiesis; D016298:Hematopoietic Cell Growth Factors / Q000502:physiology*; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D007231:Infant, Newborn; D007377:Interleukin-3 / Q000627:therapeutic use*; D008297:Male
chemical_list: D016298:Hematopoietic Cell Growth Factors; D007155:Immunologic Factors; D007377:Interleukin-3; D016178:Granulocyte-Macrophage Colony-Stimulating Factor