title: Effects of high-frequency sound on the guinea pig cochlea. Electrophysiological study using cochlear microphonics, action and endocochlear potential.
abstract: There are only a few studies investigating the effect of high-frequency sound on hearing. Authors investigated experimentally the effect of long exposure to high-frequency sound (19 and 25 kHz) below 100 dB (SPL) on guinea pig inner ear. Changes in cochlear microphonics (decrease of maximum output voltage) and especially in endocochlear potential (decrease of the absolute value of negative potential) were observed. The effects of high-frequency sound (10-30 kHz) on the inner ear were discussed.
authors.affiliation: Department of Hygiene Asahikawa Medical College, Hokkaido, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Ishida
authors.forename: T
authors.initials: T
authors.lastname: Sugisawa
authors.forename: K
authors.initials: K
authors.lastname: Yamamura
mesh_terms: D000200:Action Potentials; D000818:Animals; D015687:Cell Hypoxia; D003051:Cochlea / Q000473:pathology / Q000503:physiopathology*; D003055:Cochlear Microphonic Potentials / Q000502:physiology*; D004710:Endolymph / Q000378:metabolism* / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006168:Guinea Pigs; D008839:Microelectrodes; D009622:Noise / Q000009:adverse effects; D011188:Potassium / Q000378:metabolism; D011930:Reaction Time; D013997:Time Factors; D014465:Ultrasonics / Q000009:adverse effects*
chemical_list: D011188:Potassium