Mycobacterium gordonae: a treatable disease in HIV-positive patients.
OBJECTIVE
To evaluate the pathogenicity of Mycobacterium gordonae in patients with and without human immunodeficiency virus (HIV) infection.


METHODS
Twenty-one HIV-positive and 15 HIV-negative patients in a tertiary care center. A descriptive, case-control, and cohort study with a review of the literature with a computer-based data research.


RESULTS
The 15 HIV-negative patients had colonization only. Seven HIV-positive patients had colonization, 12 had possible disease, and 2 had dissemination. The two patients with definitive dissemination improved objectively with treatment.


CONCLUSIONS
Mycobacterium gordonae in HIV-negative patients is rarely a pathogen. In HIV-positive patients with a low CD4+ cell count, it can cause significant disease and treatment is beneficial.
Lessnau
K D
KD
Department of Pulmonary/Critical Care Medicine, Cabrini Medical Center, New York 10003.
Milanese
S
S
Talavera
W
W
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000628:therapy*; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000628:therapy*; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000628:therapy*