Bullous systemic lupus erythematosus. Report of a case with lupus erythematosus cells in the dermis.
A 20-year-old black patient with bullous systemic lupus erythematosus developed papular and vesicular lesions on the extensor surfaces of the extremities. Histologically, subepidermal blisters and papillary neutrophilic abscesses with a striking number of lupus erythematosus cells were observed. No circulating anti-basal-membrane-zone antibodies were found. By Western immunoblotting, the patient's serum showed no reactivity against epidermal or dermal extracts.
Borradori
L
L
Department of Dermatology, University Hospital, Lausanne, Switzerland.
Hohl
D
D
Monteil
M
M
Frenk
E
E
D000328:Adult; D002467:Cell Nucleus / Q000648:ultrastructure; D004817:Epidermis / Q000473:pathology; D004912:Erythrocytes / Q000473:pathology; D005337:Fibrin; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000473:pathology*; D008297:Male; D009077:Mucins; D009504:Neutrophils / Q000473:pathology; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*
D009077:Mucins; D005337:Fibrin