Primary nasal melanoma with exclusive liver metastasis: a case report.
A 50-year-old male presented with a nasal mass causing obstruction and bleeding. The initial biopsy indicated a malignant lymphoma but the subsequent biopsy diagnosed an undifferentiated carcinoma. However, histopathological study and immunohistochemical study, made a final diagnosis of nasal melanoma. Six months after the diagnosis, the patient developed exclusive liver metastasis. He responded to 1 course of intensive chemotherapy with 200 mg/m2 cisplatin and 5000 mg/m2 dacarbazine for 6 months. For patients with nasal cavity malignancy, the possibility of primary melanoma should be considered. Combination chemotherapy with intensive dose of cisplatin and dacarbazine may be a viable treatment regimen for nasal melanoma with liver metastasis.
Chiou
T J
TJ
Department of Medicine, Veterans General Hospital-Taipei, Taiwan, R.O.C.
Chen
L S
LS
Lin
S L
SL
Chen
P M
PM
D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009669:Nose Neoplasms / Q000473:pathology* / Q000628:therapy