title: Distribution of calretinin mRNA in rat spinal cord and dorsal root ganglia: a study using non-radioactive in situ hybridization histochemistry.
abstract: Using non-radioactive in situ hybridization calretinin mRNA was detected in numerous small neurons within lamina II and IV of the dorsal horn. Many labelled cells are distributed over the whole ventral horn; however, no motoneurons contained the mRNA. In dorsal root ganglia 4.9 +/- 1.7% (mean +/- S.D., n = 5 animals) of the primary afferent neurons contained calretinin mRNA. Labelled cells were of intermediate and large size with diameters ranging from 36 to 68 microns indicating that calretinin is synthesized in neurons with myelinated afferent fibers and presumably a corpuscular ending.
authors.affiliation: Physiologisches Institut, Universität Würzburg, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Heppelmann
authors.forename: P C
authors.initials: PC
authors.lastname: Emson
mesh_terms: D000818:Animals; D064032:Calbindin 2; D005727:Ganglia, Spinal / Q000166:cytology / Q000378:metabolism*; D006651:Histocytochemistry; D017403:In Situ Hybridization; D009419:Nerve Tissue Proteins / Q000235:genetics; D009474:Neurons / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D064030:S100 Calcium Binding Protein G / Q000235:genetics*; D013116:Spinal Cord / Q000166:cytology / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: C576512:Calb2 protein, rat; D064032:Calbindin 2; D009419:Nerve Tissue Proteins; D012333:RNA, Messenger; D064030:S100 Calcium Binding Protein G