A study of homologous chromosomes using a morphometric approach.
A previous study of 100 karyotyped metaphase cells has demonstrated the utility of a graphic arts tool in deriving chromosome measurements for relative length determination. In the present study we utilize this same approach to address the question: "What are the average differences in relative lengths between apparently normal homologous chromosomes?" Normal standards derived from this study will be useful for testing specific hypotheses involving heteromorphic differences between homologs. No such data on normal controls could readily be found in either An International System for Human Cytogenetic Nomenclature (1985) or elsewhere.
Mark
H F
HF
Cytogenetics Laboratory, Department of Pathology, Rhode Island Hospital and Department of Pathology and Laboratory Medicine, Brown University School of Medicine, Providence, U.S.A.
Wyandt
H E
HE
Pan
T
T
Mark
R
R
Paramenter
M
M
Campbell
W
W
Mark
Y
Y
D002875:Chromosomes; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008432:Mathematical Computing; D012016:Reference Values; D012984:Software; D014960:X Chromosome; D014998:Y Chromosome