Combined modality therapy for locally advanced penile squamous cell carcinoma.
We report here a patient who presented with locally advanced Jackson Stage IV penile squamous cell carcinoma who was managed with preoperative 5-fluorouracil, mitomycin C chemotherapy, and concurrent radiation therapy. He experienced an excellent partial response which allowed more limited surgery than would otherwise be indicated. He is still alive and well 5 years after completion of his treatment without side effects, local recurrence, or distant metastatic disease.
Pedrick
T J
TJ
Department of Radiation Oncology, Riverside Regional Cancer Institute, Columbus, OH 43214.
Wheeler
W
W
Riemenschneider
H
H
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage; D010412:Penile Neoplasms / Q000532:radiotherapy / Q000628:therapy*
D016685:Mitomycin; D005472:Fluorouracil