title: [A case of chronic necrotizing pulmonary aspergillosis treated with itraconazole].
abstract: An 84-year-old woman was admitted because of fever, hemoptysis and productive cough with infiltrative shadows in the right lung field on chest X-ray. Chronic necrotizing pulmonary aspergillosis was diagnosed on the basis of her clinical and radiographic features, positive cultures and positive serological tests. Conventional chemotherapy with fluconazole and 5-FC produced only minimal improvement. A course of itraconazole was initiated and proved to be effective.
authors.affiliation: Department of Medicine, School of Medicine, Keio University, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Terashima
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Naoki
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: M
authors.initials: M
authors.lastname: Kanazawa
authors.forename: T
authors.initials: T
authors.lastname: Kawashiro
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D001228:Aspergillosis / Q000188:drug therapy* / Q000209:etiology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D017964:Itraconazole / Q000008:administration & dosage*; D008172:Lung Diseases, Fungal / Q000188:drug therapy* / Q000209:etiology; D009336:Necrosis; D014397:Tuberculosis, Pulmonary / Q000150:complications
chemical_list: D017964:Itraconazole