title: "Syndrome X" and coronary artery disease.
abstract: BACKGROUND
  "Syndrome X" is a heterogeneous disorder that probably encompasses several disease states. The long-term prognosis in syndrome X is good, although a significant number of patients continue to experience chest pain and remain functionally limited. Several studies have reported that the development of coronary artery disease in patients with syndrome X is rare. Our experience, however, has shown that patients diagnosed as having syndrome X may develop atherosclerotic coronary artery disease over a relatively short period of time.
  
  
  METHODS
  Three patients with syndrome X were studied with repeat coronary angiography.
  
  
  CONCLUSIONS
  We describe the development of coronary artery disease in three syndrome X patients over a relatively short time after their normal coronary angiogram. Accordingly, the physician should remain alert to this possibility.
authors.affiliation: Regional Cardiac Unit, Papworth Hospital, Cambridge, England, UK.
authors.forename: A
authors.initials: A
authors.lastname: Chauhan
authors.forename: M C
authors.initials: MC
authors.lastname: Petch
authors.forename: P M
authors.initials: PM
authors.lastname: Schofield
mesh_terms: D000328:Adult; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D017566:Microvascular Angina / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D008875:Middle Aged; D011379:Prognosis