title: Five case reports of high grade non-Hodgkin's lymphoma in human immunodeficiency virus-1 negative homosexual men.
abstract: High grade non-Hodgkin's lymphoma accounts for only 5%-10% of all non-Hodgkin's lymphoma. Infection with the human immunodeficiency virus increases the risk of developing high grade, usually B-cell, lymphoma, which has been noted to occur more commonly in homosexual men. These lymphomas often have unusual clinical presentations. We report five cases of high grade non-Hodgkin's lymphoma in HIV negative homosexual men who presented to our hospital in a 13-month period. As a major centre for the treatment of the acquired immune deficiency syndrome, there may be a self-selected homosexual population attending for medical care, and thus a bias in the relative incidence of lymphoma seen in this group.
authors.affiliation: Meyerstein Institute of Clinical Oncology, Middlesex Hospital, London, UK.
authors.forename: J K
authors.initials: JK
authors.lastname: Simpson
authors.forename: W
authors.initials: W
authors.lastname: Mills
authors.forename: M F
authors.initials: MF
authors.lastname: Spittle
mesh_terms: D000328:Adult; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D018023:HIV Seronegativity; D006716:Homosexuality; D006801:Humans; D015994:Incidence; D016393:Lymphoma, B-Cell / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D008297:Male; D012307:Risk Factors