Clinical manifestations in patients on chronic dialysis with high titres of ANCA.
Eight untreated patients with an apparent renal-limited disease continued to maintain high titres of ANCA long after the onset of the disease and the start of dialysis. In spite of the high ANCA titres, three of them remained for a long time free of symptoms related to the disease. Three pts developed, at various times from the beginning of the disease, fatal pulmonary hemorrhages.
Gregorini
G
G
Department of Nephrology, University of Brescia, Italy.
Tira
P
P
Manili
L
L
Broccoli
R
R
De Marinis
S
S
Gazzotti
R M
RM
Maiorca
R
R
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000097:blood*; D005921:Glomerulonephritis / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D009195:Peroxidase / Q000276:immunology; D006435:Renal Dialysis
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D007074:Immunoglobulin G; D009195:Peroxidase