title: Bisbenzylisoquinoline alkaloids from Cyclea barbata.
abstract: Continuing studies of the alkaloidal fraction from the roots of Cyclea barbata afforded two new bisbenzylisoquinoline alkaloids, namely, (-)-2'-norlimacine [1] and (+)-cycleabarbatine [2]. The known (+)-tetrandrine-2'-beta-N-oxide [3], for which the configuration of the N-oxide function is now assigned, was identified, as were (+)-berbamine, (-)-repandine, (+)-cycleanorine, (+)-daphnandrine, (-)-curine, (+)-coclaurine, and (-)-N-methylcoclaurine.
authors.affiliation: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612.
authors.forename: H
authors.initials: H
authors.lastname: Guinaudeau
authors.forename: L Z
authors.initials: LZ
authors.lastname: Lin
authors.forename: N
authors.initials: N
authors.lastname: Ruangrungsi
authors.forename: G A
authors.initials: GA
authors.lastname: Cordell
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D044182:Benzylisoquinolines; D007546:Isoquinolines / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation
chemical_list: D000470:Alkaloids; D044182:Benzylisoquinolines; D007546:Isoquinolines; C085398:cycleabarbatine; C085399:2'-norlimacine; C009438:tetrandrine