Verruca vulgaris and radiation exposure are associated with squamous cell carcinoma of the finger.
BACKGROUND
Factors associated with the development of squamous cell carcinoma (SCC) of the finger are verruca vulgaris, radiation exposure, burns, and arsenic ingestion.


OBJECTIVE
We wish to further document the relationship between human papillomavirus (HPV) and roentgen exposure to squamous cell carcinoma of the finger.


METHODS
A retrospective study of 32 cases of digital squamous cell carcinoma seen at UCLA Medical Center was performed.


RESULTS
Ten patients (31%) had histories of verrucae at the site of the carcinoma. Eight patients (25%) had histories of x-ray therapy to the hand.


CONCLUSIONS
Our study further supports the association of verruca vulgaris and radiation exposure in the development of squamous cell carcinoma of the finger.
Kopelson
P L
PL
UCLA Division of Dermatology, VA West Los Angeles Medical Center, Jonsson Comprehensive Cancer Center, UCLA School of Medicine.
Nguyen
Q H
QH
Moy
R L
RL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020261:Arsenic Poisoning; D002056:Burns / Q000150:complications; D002278:Carcinoma in Situ / Q000209:etiology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000601:surgery; D005260:Female; D005385:Fingers; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009381:Neoplasms, Radiation-Induced; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000209:etiology* / Q000601:surgery; D014860:Warts / Q000150:complications*