title: Regulation of tetrahydrobiopterin biosynthesis in cultured hypothalamic and mesencephalic neurons by cyclic AMP dependent GTP cyclohydrolase I gene expression.
authors.affiliation: Department of Psychiatry, Wayne State University School of Medicine, Detroit, Michigan 48201.
authors.forename: K
authors.initials: K
authors.lastname: Hirayama
authors.forename: M
authors.initials: M
authors.lastname: Zhu
authors.forename: G
authors.initials: G
authors.lastname: Kapatos
mesh_terms: D015124:8-Bromo Cyclic Adenosine Monophosphate / Q000494:pharmacology*; D000818:Animals; D001708:Biopterins / Q000031:analogs & derivatives* / Q000096:biosynthesis; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004622:Embryo, Mammalian; D006136:GTP Cyclohydrolase / Q000096:biosynthesis*; D015870:Gene Expression / Q000187:drug effects; D007031:Hypothalamus / Q000201:enzymology*; D007700:Kinetics; D008636:Mesencephalon / Q000201:enzymology*; D009474:Neurons / Q000187:drug effects / Q000201:enzymology*; D009928:Organ Specificity; D051381:Rats
chemical_list: D001708:Biopterins; D015124:8-Bromo Cyclic Adenosine Monophosphate; D000242:Cyclic AMP; D006136:GTP Cyclohydrolase; C003402:sapropterin