[Lipiodol chemoembolization in the treatment of hepatic carcinoma. Our experience].
Of the alternative methods of treatment to surgery in the treatment of liver cancer, chemoembolization with Lipiodol appears to have obtained encouraging results. After a preoperative study to confirm the diagnosis and staging of the tumour, lipiodolisation is performed: a mix of Adriamycin, Iopamidol and Lipiodol is injected using selective catheterism of the hepatic artery; gelfoam is then added. Lipiodol selectively localises in the hepatocarcinoma and has a distal embolising effect on the vessels of the tumour, thus necrotising it, acting as a carrier for chemotherapy. Since july 1990 a total of 15 hepatocarcinoma have been observed: 6 in healthy livers and 9 in cirrhotic livers; 3 patients recovered after radical surgery, 1 patient underwent associated surgery and chemoembolization, whereas in 11 the only therapy was chemoembolization, at six monthly intervals. Lipiodolisation enabled a better diagnosis to be made and was found to be a valuable therapeutic aid both when used alone in Inoperable patients and in association with non-radical surgery.
Padula
G
G
Istituto di Patologia Speciale Chirurgica, Facoltà di Medicina e Chirurgia, Università degli Studi di Sassari.
Derosas
M
M
Carpanese
L
L
Pisano
I
I
Deiana
A
A
Serra
G
G
Trignano
M
M
D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000628:therapy*; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D004621:Embolization, Therapeutic / Q000379:methods*; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage*; D007479:Iopamidol / Q000008:administration & dosage; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging / Q000628:therapy; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D014057:Tomography, X-Ray Computed
D007459:Iodized Oil; D004317:Doxorubicin; D007479:Iopamidol
La chemioembolizzazione con Lipiodol nel trattamento del carcinoma epatico. Nostra esperienza.