title: Effect of a short maximal physical exercise on the eosinophil cationic protein.
abstract: Eosinophil cationic protein (ECP) has been shown to be a marker of eosinophil granulocyte activation. In 10 healthy young subjects the plasma concentrations of ECP were measured before and after a graded maximal bicycle exercise test. The analyses were carried out 30 min before and immediately before exercise, immediately after exercise and 20 and 45 min later. The post-exercise values were corrected for plasma volume changes which were calculated from hematocrit and hemoglobin values. Immediately post-exercise the ECP increased significantly (p < 0.01) from 1.25 +/- 0.28 at rest to 2.40 +/- 0.59 micrograms/l. Twenty and 45 min later the values normalized and significant differences from the pre-exercise values could no longer be measured. The results provide strong evidence for an activation of eosinophil granulocytes after a short maximal exercise.
authors.affiliation: Institute for Cardiology and Sports Medicine, German Sport University Cologne.
authors.forename: B
authors.initials: B
authors.lastname: Dufaux
authors.forename: O
authors.initials: O
authors.lastname: Heine
authors.forename: U
authors.initials: U
authors.lastname: Prinz
authors.forename: C
authors.initials: C
authors.lastname: Soll
authors.forename: R
authors.initials: R
authors.lastname: Rost
mesh_terms: D000328:Adult; D001798:Blood Proteins / Q000378:metabolism*; D047091:Eosinophil Granule Proteins; D004804:Eosinophils / Q000378:metabolism*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D010953:Plasma Volume; D012260:Ribonucleases; D013997:Time Factors
chemical_list: D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D012260:Ribonucleases