[Isoptin-Retard 240 mg in the treatment of mild and moderate arterial hypertension].
To elucidate a hypotensive effect of isoptin-retard in a dose 240 mg/day, 17 males with mild and moderate hypertension receiving the drug underwent 24-h monitoring by SpaceLabs 5300 and pressure loading. A significant lowering of both mean systolic and diastolic pressure was found both in daytime and at night. A hypotensive effect persisted for 2 months. No case of serious cardiovascular complications, of noticeable shifts in blood biochemistry was reported.
Arabidze
G G
GG
Rogoza
A N
AN
Dmitriev
V V
VV
Metelitsa
T V
TV
Domba
G Iu
GIu
Sitina
V K
VK
D001794:Blood Pressure / Q000187:drug effects; D015924:Blood Pressure Monitors; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D014700:Verapamil / Q000627:therapeutic use*
D003692:Delayed-Action Preparations; D014700:Verapamil
Izoptin-retard 240 mg pri lechenii miagkoĭ i umerennoĭ arterial'noĭ gipertonii.