title: Investigation of impaired ovarian function as a contributing factor to infertility in women with pelvic adhesions.
abstract: A prospective study was performed to determine whether a relationship exists between infertility as a result of pelvic adhesions, and raised follicle stimulating hormone (FSH). A total of 66 patients, who had a diagnostic laparoscopy and dye performed as part of their infertility work-up, had an early cycle serum FSH drawn one to two cycles after this procedure. Patients were divided into two groups, one with pelvic adhesions as a result of surgery, infection or endometriosis, and a control group consisting of those with a normal pelvis at laparoscopy or with minimal/mild endometriosis without adhesions. In the adhesion group, a correlation was noted between American Fertility Society (AFS) adhesion score and basal FSH concentration, although all FSH values for this group were within the normal range. This study suggests a correlation between pelvic adhesions and ovarian compromise, but a larger study involving more severe cases of adhesions is required to determine whether this finding is of clinical importance.
authors.affiliation: University Department of Obstetrics and Gynaecology, Jessop Hospital for Women, Sheffield, UK.
authors.forename: M C
authors.initials: MC
authors.lastname: Bowman
authors.forename: I D
authors.initials: ID
authors.lastname: Cooke
authors.forename: E A
authors.initials: EA
authors.lastname: Lenton
mesh_terms: D001481:Basal Metabolism; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000503:physiopathology*; D008597:Menstrual Cycle / Q000502:physiology; D010053:Ovary / Q000503:physiopathology*; D010388:Pelvis; D011446:Prospective Studies; D000267:Tissue Adhesions / Q000503:physiopathology*
chemical_list: D005640:Follicle Stimulating Hormone