Reversed diastolic blood flow at duplex Doppler. A sign of poor prognosis in renal transplants.
In 25 renal allografts out of 253 with graft dysfunction a reversed diastolic blood flow was observed at duplex ultrasonography during the first post-transplant month. Eleven grafts were lost and 14 survived. The cause of graft loss was arterial thrombosis (n = 1), venous thrombosis or obstruction (n = 4), steroid resistant acute rejection (n = 4) and acute tubular necrosis (ATN) (n = 2). The cause of graft dysfunction in the surviving grafts was ATN (n = 7) and acute allograft rejection (n = 7). Grafts with only peak-like or low velocity continuous diastolic flow reversal had a better prognosis (3 out of 15 were lost) than grafts with any other type of reversed flow pattern (8 out of 10 were lost). This difference was statistically significant (p < 0.01).
Saarinen
O
O
Department of Radiology, University Hospital, Helsinki, Finland.
Salmela
K
K
Ahonen
J
J
Edgren
J
J
D001707:Biopsy, Needle; D001783:Blood Flow Velocity / Q000502:physiology; D003971:Diastole; D006084:Graft Rejection / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000000981:diagnostic imaging* / Q000473:pathology / Q000502:physiology*; D007683:Kidney Tubular Necrosis, Acute / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D011379:Prognosis; D012079:Renal Circulation / Q000502:physiology*; D013924:Thrombophlebitis / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D014463:Ultrasonography; D014689:Venous Insufficiency / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology