title: [Cardiodynamics and myocardial contractile reserve in patients with hypertrophic cardiomyopathy].
abstract: Cardiodynamics and myocardial contractile reserve were studied in 60 patients with hypertrophic cardiomyopathy by using radionuclide ventriculography at rest and during graded exercise test. All findings that characterize cardiodynamics (normal or higher overall ejection fraction and stroke volume or lower end-systolic volume, higher maximum ejection rate) show the contractility of the left ventricle in patients with hypertrophic cardiomyopathy which can be regarded to be more severe. During graded exercise test, in patients with hypertrophic cardiomyopathy three types of reactions were identified: (1) positive inotropic effect; (2) negative inotropic effect; (3) intermediate (deviation of major cardiodynamic parameters was no more than 20-25% of the baseline levels). Identification of the above types allows one to assess the presence and conditions of myocardial contractile reserve implementation in these patients and to objectivize the choice of corrective drugs.
authors.forename: G V
authors.initials: GV
authors.lastname: Ianovskiĭ
authors.forename: N P
authors.initials: NP
authors.lastname: Stroganova
authors.forename: Zh M
authors.initials: ZhM
authors.lastname: Vysotskaia
authors.forename: E V
authors.initials: EV
authors.lastname: Dmitrichenko
mesh_terms: D000293:Adolescent; D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000503:physiopathology*; D004452:Echocardiography; D005080:Exercise Test; D015637:Gated Blood-Pool Imaging; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction
vernacular_title: Sostoianie kardiodinamiki i sokratitel'nyĭ rezerv miokarda u bol'nykh s gipertroficheskoĭ kardiomiopatieĭ.