[A rapid method of HbA1c determination in a pediatric diabetic patient sample].
A new Method for HbA1c measurements (Abbott vision) was evaluated. 107 patients (45 F, 62 M) of a paediatric diabetes clinic participated. The mean age was 14.9 (5.8-26.3) years, the mean duration of diabetes was 7.6 (0.1-21.1) years. Measurements were performed immediately after capillary blood sampling, the result was available within 15 min. The automated HPLC-system Diamat was used as a reference method, blood samples were stored at 4 degrees C and analysed within 24 h after blood sampling. There was a close correlation between both methods (r = 0.96, P < 0.0001). In the lower range the results measured by Abbott Vision were slightly lower, whereas in the higher range the results were slightly higher (HbA1c (Abbott) = 1.53 + HbA1c (Diamat).0.84). The accuracy seems to be satisfactory for estimating metabolic control. The HbA1c-result is available within 15 min which means a major advantage for the management of children and adolescents with type I diabetes.
Schwingshandl
J
J
Universitäts-Kinderklinik, Graz.
Stübchen-Kirchner
H
H
Borkenstein
M
M
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002846:Chromatography, Affinity; D002851:Chromatography, High Pressure Liquid; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000175:diagnosis; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic
D006442:Glycated Hemoglobin
Schnellbestimmungsmethode von HbA1c in einem pädiatrisch diabetologischen Patientengut.