[Regulation of enzymes of the first and last stage of lysine biosynthesis in Streptococcus bovis and Enterococcus faecium].
Regulation of aspartate kinase and diaminopimelate decarboxylase activities in Streptococcus bovis and Enterococcus faecium cell-free extracts was studied. The levels of synthesis of aspartate kinase and diaminopimelate decarboxylase in both microorganisms are growth-dependent. The synthesis of these enzymes is depressed by lysine, but the activity of aspartate kinase is induced by addition of this amino acid and threonine to the reaction system. Meso-diaminopimelate dehydrogenase activity was not found in the extracts of Streptococcus bovis and Enterococcus faecium. The data excludes the possibility of lysine formation via six enzyme reactions.
Kal'cheva
E O
EO
Faĭziev
M M
MM
Shanskaia
V O
VO
Maliuta
S S
SS
D001222:Aspartate Kinase / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000378:metabolism*; D001426:Bacterial Proteins; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000378:metabolism*; D002384:Catalysis; D002474:Cell-Free System; D016984:Enterococcus faecium / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D008239:Lysine / Q000096:biosynthesis*; D016985:Streptococcus bovis / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism
D001426:Bacterial Proteins; D001222:Aspartate Kinase; D002262:Carboxy-Lyases; C079912:LysA protein, Bacteria; C020031:diaminopimelic acid decarboxylase; D008239:Lysine
Reguliatsiia fermentov pervoĭ i posledneĭ stadiĭ biosinteza lizina u Streptococcus bovis i Enterococcus faecium.