title: [The knowledge base of the Hepaxpert I System: automatic interpretation of Hepatitis A and B serology].
abstract: The knowledge base of Hepaxpert-I, a medical expert system for interpretive analysis of hepatitis A and B serologic findings, contains 13 rules for hepatitis A and 106 rules for hepatitis B serology. Formally, the construction of the knowledge base was done by forming a partition of the sets of possible serologic finding patterns--64 for hepatitis A and 4096 for hepatitis B serology--induced by an equivalence relation, divides the elements of the sets into disjoint subsets, the equivalence classes. Each equivalence class is represented as one If-Then rule that assigns to every member of the equivalence class one interpretive text. The partition of the possible finding patterns into equivalence classes and the disposal of one and only one interpretive text for each equivalence class made the creation of a very practical and efficient computer program for the precise interpretation of any finding pattern of serologic tests for hepatitis A and B possible. The complete set of the provided If-Then rules is represented in this paper.
authors.affiliation: Section on Medical Informatics, Stanford University School of Medicine, CA 94305-5479.
authors.forename: K P
authors.initials: KP
authors.lastname: Adlassnig
authors.forename: W
authors.initials: W
authors.lastname: Horak
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation*; D005103:Expert Systems; D006506:Hepatitis A / Q000175:diagnosis* / Q000276:immunology; D035922:Hepatitis A Antibodies; D035921:Hepatitis A Antigens; D006508:Hepatitis Antibodies / Q000032:analysis; D006509:Hepatitis B / Q000175:diagnosis* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000032:analysis; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D011237:Predictive Value of Tests; D012698:Serologic Tests / Q000295:instrumentation*
chemical_list: D000956:Antigens, Viral; D035922:Hepatitis A Antibodies; D035921:Hepatitis A Antigens; D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens
vernacular_title: Die Wissensbasis des Hepaxpert-I-Systems: Automatische Interpretation der Hepatitis-A und -B-Serologie.