Rates and outcomes of diabetic end-stage renal disease among registered native people in Saskatchewan.
OBJECTIVE
To determine the rates and outcomes of diabetic end-stage renal disease (ESRD) among registered native people and non-native people in Saskatchewan.


METHODS
Retrospective population-based study using data from the Canadian Organ Replacement Registry.


METHODS
Saskatchewan.


METHODS
All patients with diabetic ESRD diagnosed between Jan. 1, 1981, and Dec. 31, 1990.


METHODS
Incidence rates of diabetic ESRD in the general population, rates of diabetic ESRD among patients with diabetes mellitus, nature of initial dialysis treatment, length of survival from start of dialysis, cause of death and renal transplant rates.


RESULTS
The 10-year incidence rates of diabetic ESRD were higher among all age groups among registered native people than among non-native people. The overall relative risk ratio for native people was 16.2. When a higher prevalence of diabetes among native people was taken into account, native diabetic people were still seven times as likely as non-native diabetic people to manifest diabetic ESRD. The median survival from start of dialysis was under 2 years in both groups, but more native people died of stroke and more non-native people died of heart disease. Non-native diabetic people were more likely than native diabetic people to receive renal transplants.


CONCLUSIONS
Although the overall incidence of diabetic ESRD in Saskatchewan is increasing, registered native people have a disproportionate risk for this serious complication.
Dyck
R F
RF
Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon.
Tan
L
L
D000328:Adult; D017677:Age Distribution; D000368:Aged; D002423:Cause of Death; D003928:Diabetic Nephropathies / Q000150:complications / Q000208:ethnology* / Q000401:mortality; D005260:Female; D006801:Humans; D015994:Incidence; D007198:Indians, North American / Q000706:statistics & numerical data*; D007676:Kidney Failure, Chronic / Q000208:ethnology* / Q000209:etiology / Q000401:mortality; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012525:Saskatchewan / Q000453:epidemiology; D017678:Sex Distribution; D016019:Survival Analysis