title: [Use of cholinesterase inhibitors in Alzheimer disease].
abstract: According to the cholinergic theory of Alzheimer's disease, the cognitive failure depends on a deficit in acetylcholine. The study reported above examines the efficacy and tolerability of cholinesterase inhibitors, such as tetrahydroamino acridine (THA), for the management of this pathology.
authors.affiliation: II Divisione di Geriatria, Ospedale dell'Addolorata di Roma.
authors.forename: M
authors.initials: M
authors.lastname: Sampalmieri
authors.forename: M P
authors.initials: MP
authors.lastname: Troiani
authors.forename: M
authors.initials: M
authors.lastname: Servi
mesh_terms: D000109:Acetylcholine / Q000172:deficiency*; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism; D002800:Cholinesterase Inhibitors / Q000008:administration & dosage*; D003072:Cognition Disorders / Q000188:drug therapy / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D013619:Tacrine / Q000008:administration & dosage*
chemical_list: D002800:Cholinesterase Inhibitors; D013619:Tacrine; D000109:Acetylcholine
vernacular_title: Impiego degli inibitori della colinesterasi nella malattia di Alzheimer.