Systemic ceroid-lipofuscinosis in a Japanese domestic cat.
An 11-month-old castrated male Japanese domestic cat was euthanized because of neurological symptoms such as shivering and difficulty of walking. Histopathological examination showed glial proliferation and marked deposition of ceroid-lipofuscin in the neuronal and glial cells of the brain. Ceroid-lipofuscin was deposited also in reticuloendothelial cells of the liver, spleen and some lymph nodes.
Nakayama
H
H
Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Japan.
Uchida
K
K
Shouda
T
T
Uetsuka
K
K
Sasaki
N
N
Goto
N
N
D000818:Animals; D001284:Atrophy; D001921:Brain / Q000473:pathology*; D002371:Cat Diseases; D002415:Cats; D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D008297:Male; D017628:Microglia / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009472:Neuronal Ceroid-Lipofuscinoses / Q000473:pathology / Q000662:veterinary*; D009919:Orchiectomy