[Doppler microprobe allows evaluation of local coronary circulation].
The local coronary flow in 42 patients (mean age: 59 +/- 9 years) with ischemic heart disease was assessed by means of an 0.018" intracoronary Doppler guidewire. Study population was divided into two groups: group I--"normal vessels" (diameter stenosis < 30%) and group II--"stenosis vessels" (diameter stenosis > 60%). Measurements of: averaged peak velocity (APV), diastolic-systolic velocity ratio (DSVR) were performed in proximal segments of normal vessels and proximally to stenosis in group II. APV and DSVR were recorded at rest (bas) and during papaverine induced hyperemia. Coronary flow reserve (CFR) was calculated as ratio hyperemic and resting values of APV. Mean value of APV at rest was highest for left main stem, lowest for venous by-passes (SVBG) but did not differ among three coronary arteries (LAD, LCX, RCA). CFR value was significantly higher for group I then for group II (2.75-3.3 vs 1.8-2.0) but did not differ significantly among particular arteries in both groups. Mean value of DSVRbas in both examined groups was lowest for right coronary artery and for SVBG (ca. 1.0) and did not change significantly during hyperemia. This value was significantly higher (ca. 2.0) for left coronary arteries (LAD, LCX) then for RCA and SVBG and significantly decreased after administration of papaverine.
Gil
R
R
Klinika Kardiologii Pomorskiej Akademii Medycznej, Szczecin.
Di Mario
C
C
Serruys
P W
PW
Kornacewicz-Jach
Z
Z
Kazmierczak
J
J
D000368:Aged; D003326:Coronary Circulation / Q000187:drug effects / Q000502:physiology*; D003327:Coronary Disease / Q000503:physiopathology*; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation*; D008875:Middle Aged; D010208:Papaverine / Q000494:pharmacology; D012016:Reference Values
D010208:Papaverine
Mikrosonda dopplerowska umozliwia ocene miejscowego krazenia wieńcowego.