title: A simplified method for the preparation of succinimidyl carbonate polyethylene glycol for coupling to proteins.
abstract: An improved method for the activation of polyethylene glycol with commercially available succinimidyl carbonate is described. The activated polyethylene glycol was coupled to proteins in high yield.
authors.affiliation: Department of Biophysics, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: T
authors.initials: T
authors.lastname: Miron
authors.forename: M
authors.initials: M
authors.lastname: Wilchek
mesh_terms: D002254:Carbonates / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D013388:Succinimides / Q000737:chemistry*
chemical_list: D002254:Carbonates; D011506:Proteins; D013388:Succinimides; C085786:succinimidyl carbonate; D011092:Polyethylene Glycols; C028210:monomethoxypolyethylene glycol