title: [Possibility of detecting phenobarbital in biological fluids after taking a therapeutic dose].
abstract: The authors have examined the possibility of detecting phenobarbital in normal subjects' urine after a single intake of a therapeutic dose and in experimental animals' (rats) organs after a single intake and after a course of administration of the drug. They came to a conclusion that the positive results of the qualitative method of the drug detection in biologic fluids, particularly in case of death at the site of the accident, are not sufficient for the expert to substantiate the cause of death.
authors.forename: M I
authors.initials: MI
authors.lastname: Krut'
authors.forename: M N
authors.initials: MN
authors.lastname: Gorskaia
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000737:chemistry*; D002855:Chromatography, Thin Layer; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008875:Middle Aged; D010634:Phenobarbital / Q000008:administration & dosage / Q000032:analysis* / Q000506:poisoning; D051381:Rats; D013053:Spectrophotometry; D013997:Time Factors
chemical_list: D010634:Phenobarbital
vernacular_title: O vozmozhnosti vyiavleniia fenobarbitala v biologicheskikh zhidkostakh posle priema lechebnoĭ dozy.