[Studies on chemotherapeutic agents against Schistosomiasis japonica: synthesis of benzimidazole derivatives].
A series of 3-(1H-benzimidazole-2)-2-propenoic acid derivatives were prepared and tested for schistosomicidal activity. The acid was proved to be a cis-isomer. Preliminary pharmacological tests showed that these compounds were in effective.
Ying
H Q
HQ
Nan jing Institute of Wild Plants.
Dai
X F
XF
D000818:Animals; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use; D051379:Mice; D015394:Molecular Structure; D012554:Schistosomiasis japonica / Q000517:prevention & control; D012556:Schistosomicides / Q000138:chemical synthesis* / Q000627:therapeutic use; D013237:Stereoisomerism
D001562:Benzimidazoles; D012556:Schistosomicides