title: [The experiences of a large amount of steroid therapy for symptomatic vasospasm after subarachnoid hemorrhage: clinical analysis of 21 cases].
abstract: Among 48 cases of subarachnoid hemorrhage, 21 cases (43.8%) showed symptomatic vasospasm. We attempted treatment, using a large amount of steroid therapy for them in accord with our own protocol. In the 21 cases who received steroid therapy for symptomatic vasospasm, 18 cases (85.7%) showed improvement of their symptoms. This was especially evident in about 8 cases where the steroid effect was remarkable. There was a serious side effect, GI--tract bleeding, in one case. Although the effect of the steroid therapy was evident for slight or moderate spasm cases, 5 severe spasm cases responded poorly. We concluded that a large amount of steroid therapy was effective for slight or moderate symptomatic vasospasm cases, and that in severe ones possibly another therapy combined with steroid therapy would be necessary.
authors.affiliation: Kobayashi Neurosurgical and Neurological Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Yasukawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kamijou
authors.forename: G
authors.initials: G
authors.lastname: Momose
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Kuroyanagi
authors.forename: N
authors.initials: N
authors.lastname: Morota
authors.forename: T
authors.initials: T
authors.lastname: Unoki
mesh_terms: D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage*; D002546:Ischemic Attack, Transient / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D013345:Subarachnoid Hemorrhage / Q000150:complications*
chemical_list: D006854:Hydrocortisone