Correction of thrombocytopenia with dapsone in the primary antiphospholipid syndrome.
A 25-year-old woman with the antiphospholipid syndrome developed severe thrombocytopenia (18 x 10(9)/l), which was promptly corrected by treatment with dapsone. The mechanisms for the apparent therapeutic effect of dapsone are discussed.
Durand
J M
JM
Department of Internal Medicine, CHU Sainte Marguerite, Marseille, France.
Lefevre
P
P
Kaplanski
G
G
Cretel
E
E
Mongin
M
M
Soubeyrand
J
J
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D003622:Dapsone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D013921:Thrombocytopenia / Q000150:complications* / Q000188:drug therapy*
D003622:Dapsone