The outbreak of equine influenza (H3N8) in the United Kingdom in 1989: diagnostic use of an antigen capture ELISA.
In July 1989 influenza A/equine-2 (H3N8) was isolated from a nasopharyngeal swab taken from a non-thoroughbred horse exhibiting acute clinical respiratory disease. This was the first isolation of equine influenza virus in the United Kingdom since 1981. Subsequent investigations of acute respiratory disease in horses indicated that the infection was dispersed throughout the UK. However, unlike the previous epidemic of 1979, the first horses from which the virus was isolated had been vaccinated. This outbreak of influenza provided an opportunity to evaluate an antigen capture ELISA, directed against the influenza virus nucleoprotein, as a rapid method for detecting virus in the nasopharyngeal secretions of naturally infected horses.
Livesay
G J
GJ
Department of Infectious Diseases, Animal Health Trust, Newmarket, Suffolk.
O'Neill
T
T
Hannant
D
D
Yadav
M P
MP
Mumford
J A
JA
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000276:immunology; D004196:Disease Outbreaks / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000453:epidemiology* / Q000276:immunology; D006736:Horses; D053123:Influenza A Virus, H3N8 Subtype; D009980:Influenza A virus / Q000276:immunology; D008297:Male; D009976:Orthomyxoviridae Infections / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*; D006113:United Kingdom / Q000453:epidemiology
D000914:Antibodies, Viral; D000956:Antigens, Viral