[Effect of immunomodulators on selected functions of neonatal polymorphonuclear neutrophils in vitro].
Phagocytosis, bactericidal capacity, production of superoxide anions O2- and expression of receptor for the Fc portion of IgG of polymorphonuclear neutrophils (PMN) were estimated in umbilical venous blood of neonates and their mothers. We also evaluated the influence of immunomodulating agents on these parameters. The influence of the maternal serum on the function of neonatal PMN was examined. The obtained results indicate that functional defect of neonatal PMN may be corrected under the influence of the maternal serum and/or immunomodulating agents.
Wysocki
H
H
Instytutu Chorób Wewnetrznych, Akademii Medycznej im. K. Marcinkowskiego, Poznaniu.
Orzeszko-Spaczyńska
A
A
Wykretowicz
A
A
Wierusz-Wysocka
B
B
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D066298:In Vitro Techniques; D007231:Infant, Newborn; D009504:Neutrophils / Q000187:drug effects*; D010585:Phagocyte Bactericidal Dysfunction / Q000188:drug therapy*; D011247:Pregnancy / Q000276:immunology
D000276:Adjuvants, Immunologic; D007074:Immunoglobulin G
Wpływ immunomodulatorów na wybrane funkcje granulocytów obojetnochłonnych noworodka in vitro.