Neutrophil-catalysed dimerisation of tyrosyl peptides.
Evidence is given that tyrosyl-peptides are dimerised by polymorphonuclear leukocytes leading to a new family of compounds. The products formed are homo- and hetero-dimeric peptides with linkage between the tyrosyl residues. This corresponds to a dityrosine structure as determined by analytic and spectroscopic data.
Salman-Tabcheh
S
S
INSERM unité 58, Montpellier, France.
Rabgaoui
N
N
Torreilles
J
J
D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D006735:Horseradish Peroxidase / Q000378:metabolism; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D007700:Kinetics; D046911:Macromolecular Substances; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009504:Neutrophils / Q000378:metabolism*; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism*; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014443:Tyrosine / Q000378:metabolism*
D046911:Macromolecular Substances; D010455:Peptides; D014443:Tyrosine; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase; D013755:Tetradecanoylphorbol Acetate