title: Enzyme-activated antagonists of the strychnine-insensitive glycine/NMDA receptor.
authors.affiliation: Marion Merrell Dow Research Institute, Cincinnati, Ohio 45215.
authors.forename: F G
authors.initials: FG
authors.lastname: Salituro
authors.forename: R C
authors.initials: RC
authors.lastname: Tomlinson
authors.forename: B M
authors.initials: BM
authors.lastname: Baron
authors.forename: M G
authors.initials: MG
authors.lastname: Palfreyman
authors.forename: I A
authors.initials: IA
authors.lastname: McDonald
authors.forename: W
authors.initials: W
authors.lastname: Schmidt
authors.forename: H Q
authors.initials: HQ
authors.lastname: Wu
authors.forename: P
authors.initials: P
authors.lastname: Guidetti
authors.forename: R
authors.initials: R
authors.lastname: Schwarcz
mesh_terms: D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D002540:Cerebral Cortex / Q000201:enzymology; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D005998:Glycine / Q000037:antagonists & inhibitors* / Q000378:metabolism; D007700:Kinetics; D007737:Kynurenine / Q000031:analogs & derivatives* / Q000378:metabolism*; D008190:Lyases; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013331:Strychnine / Q000494:pharmacology*; D000637:Transaminases / Q000378:metabolism*
chemical_list: D016194:Receptors, N-Methyl-D-Aspartate; D007737:Kynurenine; C027883:4-chlorokynurenine; D000637:Transaminases; C427605:glutamine - phenylpyruvate transaminase; C021481:kynurenine-oxoglutarate transaminase; D008190:Lyases; D013331:Strychnine; D005998:Glycine