title: Cloning and characterization of Atlantic salmon (Salmo salar) serum transferrin cDNA.
abstract: Characterization of Atlantic salmon serum transferrin cDNA representing a near full-length transferrin mRNA revealed a 2,070-bp open reading frame encoding a protein of 690 amino acids. The predicted protein contains an 18 amino acids' long signal sequence and shows 49% amino acid positional identity with Xenopus laevis transferrin and human serum transferrin. On the basis of sequence differences obtained from different salmon transferrin cDNA clones, 2 distinct classes of transferrin mRNA were identified. Both variants were present together in genomic DNA from haploid embryos, demonstrating that Atlantic salmon have 2 transferrin genes per haploid complement. Salmon transferrin is expressed mainly in the liver.
authors.affiliation: AKVAFORSK (Institute of Aquaculture Research), As, Norway.
authors.forename: A M
authors.initials: AM
authors.lastname: Kvingedal
authors.forename: K A
authors.initials: KA
authors.lastname: Rørvik
authors.forename: P
authors.initials: P
authors.lastname: Alestrøm
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics*; D008969:Molecular Sequence Data; D012474:Salmon / Q000235:genetics*; D014168:Transferrin / Q000032:analysis / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; D014168:Transferrin