title: Acute third cranial nerve ophthalmoplegia: possible pathogenesis from alpha-II-interferon treatment.
abstract: We report the case of a 67 year old man with acute ophthalmoplegia due to extensive damage to the fibers innervating the extrinsic muscles of the left third cranial nerve. The condition was secondary to protracted treatment with alpha-II-interferon for a HCV virus chronic active hepatopathy.
authors.affiliation: Divisione di Neurologia, Ospedale S. Giovanni Calibita Fatebenefratelli, Isola Tiberina, Roma.
authors.forename: L
authors.initials: L
authors.lastname: Pacifici
authors.forename: F
authors.initials: F
authors.lastname: Passarelli
authors.forename: G
authors.initials: G
authors.lastname: Papa
authors.forename: L
authors.initials: L
authors.lastname: Cannone
authors.forename: P M
authors.initials: PM
authors.lastname: Rossini
mesh_terms: D000208:Acute Disease; D000368:Aged; D003389:Cranial Nerve Diseases / Q000139:chemically induced; D006526:Hepatitis C / Q000188:drug therapy; D006521:Hepatitis, Chronic / Q000188:drug therapy; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D009802:Oculomotor Nerve / Q000187:drug effects*; D009886:Ophthalmoplegia / Q000139:chemically induced*
chemical_list: D016898:Interferon-alpha