title: Immunohistochemical distribution of leucocyte antigens in lymphoid tissues of cynomolgus monkeys (Macaca fascicularis).
abstract: Crossreactivity of antibodies to human leucocyte antigens with lymphoid tissues of cynomolgus monkeys was studied by immunohistochemistry and immunoblotting. Of a total of 54 clusters of differentiation (CD) antigens, 39 were expressed essentially with the same immunostaining patterns in the monkey as in human lymphoid tissues. By immunoblotting L26 (CD20) detected a 35 Kd molecule in the monkey lymph node. Our observations indicated that most of the CD antigens are expressed and can be studied in lymphoid tissues of cynomolgus monkeys.
authors.affiliation: Immunopathology Lab., Karolinska Institute, Stockholm, Sweden.
authors.forename: S L
authors.initials: SL
authors.lastname: Li
authors.forename: E
authors.initials: E
authors.lastname: Kaaya
authors.forename: H
authors.initials: H
authors.lastname: Feichtinger
authors.forename: G
authors.initials: G
authors.lastname: Biberfeld
authors.forename: P
authors.initials: P
authors.lastname: Biberfeld
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D015703:Antigens, CD / Q000032:analysis*; D000943:Antigens, Differentiation / Q000032:analysis*; D015153:Blotting, Western; D003429:Cross Reactions; D006801:Humans; D007124:Immunoenzyme Techniques; D008221:Lymphoid Tissue / Q000276:immunology*; D008252:Macaca fascicularis / Q000276:immunology*; D008954:Models, Biological
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D000943:Antigens, Differentiation