[Status of the pool of hematopoietic stem cells in the peripheral blood in patients with lung cancer before and during polychemotherapy].
The pool of hematopoietic cells-precursors from the peripheral blood of patients with lung cancer stage III-IV was characterized by reduced number of circulating cells-precursors of granulomonocyto-(CFU-GM) and erythropoiesis (CFU-E). In the course of antitumor chemotherapy the counts of CFU-GM and CFU-E diminished 2 and 4-fold, respectively. The prednisolone functional test determined that depletion of CFU-GM and CFU-E pools in the peripheral blood was preceded with lowered pool reserve for hematopoietic precursors.
Gol'dberg
V E
VE
Abramova
E V
EV
Kulagina
I V
IV
Gumilevskiĭ
B Iu
BIu
Dygaĭ
A M
AM
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006412:Hematopoietic Stem Cells / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged
Sostoianie pula krovetvornykh kletok-predshestvennikov perifericheskoĭ krovi u bol'nykh rakom legkogo do i v usloviiakh provedeniia polikhimioterapii.