Comparison of binding and activity of 8-alkyl-pterins and 8-alkyl-N5-deaza-pterins with dihydrofolate reductase.
Ivery
M T
MT
Department of Biochemistry, University of Sydney, NSW, Australia.
Gready
J E
JE
D000478:Alkylation; D000818:Animals; D002645:Chickens; D005493:Folic Acid Antagonists / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D015394:Molecular Structure; D011622:Pterins / Q000378:metabolism* / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013762:Tetrahydrofolate Dehydrogenase / Q000737:chemistry* / Q000378:metabolism*; D013816:Thermodynamics
D005493:Folic Acid Antagonists; D011622:Pterins; D013762:Tetrahydrofolate Dehydrogenase