title: Caries-preventive effect of two different topical fluoride concentrations with two different frequencies of application in preschool children.
abstract: The effects of standard topical amine fluoride solution (1% F) and a low-fluoride solution (0.5% F) with two different frequencies of application (5 and 10 times a year) on 2 years dental caries increment were compared in a double-blind clinical trial involving 199 kindergarten children. The results suggest that increased frequency of application of a low fluoride topical solution (10 times a year) may provide caries protection in preschool children with relatively high caries activity.
authors.affiliation: Department of Pharmacology, Faculty of Dentistry, University of Zagreb, Croatia.
authors.forename: I
authors.initials: I
authors.lastname: Lincir
authors.forename: K
authors.initials: K
authors.lastname: Rosin-Grget
mesh_terms: D000704:Analysis of Variance; D016009:Chi-Square Distribution; D002675:Child, Preschool; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D004311:Double-Blind Method; D005460:Fluorides, Topical / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D015588:Observer Variation
chemical_list: D005460:Fluorides, Topical