Prostanoids and related compounds. VI. Synthesis of isoindolinone derivatives possessing inhibitory activity for thromboxane A2 analog (U-46619)-induced vasoconstriction.
Kato
Y
Y
School of Pharmaceutical Sciences, University of Shizuoka, Japan.
Takemoto
M
M
Achiwa
K
K
D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; D000818:Animals; D007211:Indoles / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D011450:Prostaglandin Endoperoxides, Synthetic / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D013552:Swine; D013928:Thromboxane A2 / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors; D014661:Vasoconstriction / Q000187:drug effects*; D014662:Vasoconstrictor Agents / Q000037:antagonists & inhibitors*
D007211:Indoles; D011450:Prostaglandin Endoperoxides, Synthetic; D014662:Vasoconstrictor Agents; D013928:Thromboxane A2; D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid