title: Case report: malignant giant cell tumour of the pancreas presenting as a large pancreatic cyst.
abstract: Carcinoma of the pancreas is a common tumour. Histologically, the majority are adenocarcinomas of duct origin. Carcinomas of the pancreas containing giant cells are uncommon and those containing osteoclast-type tumour cells are very rare. We report a case of malignant giant cell tumour presenting as an extremely large, thin walled haemorrhagic cyst of the pancreas. This tumour is most unusual in that the wall is composed of multiple highly pleomorphic malignant-looking multinucleated giant cells as well as numerous osteoclast-like giant cells in a stroma of small spindle shaped mononuclear cells.
authors.affiliation: Brenthurst Clinic, Johannesburg, South Africa.
authors.forename: R
authors.initials: R
authors.lastname: Scott
authors.forename: J
authors.initials: J
authors.lastname: Jersky
authors.forename: G
authors.initials: G
authors.lastname: Hariparsad
mesh_terms: D005870:Giant Cell Tumors / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D010181:Pancreatic Cyst / Q000000981:diagnostic imaging / Q000209:etiology*; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography