Butchers' warts: no evidence for person to person transmission of HPV7.
The distribution of warts due to HPV7 in workers in six abattoirs and 103 retail and wholesale butcheries has been studied to determine whether the high prevalence of HPV7 in the meat trade is the result of enhanced person to person transmission, or whether it is a ubiquitous virus which is activated by an unknown factor in meat. Warts were detected in 164 of 486 men. Scrapings were taken from 156 men, and HPV DNA was found in 112 samples, 74 of which contained HPV7. HPV7 was found in 36 workplaces, and there was no evidence of clustering of cases, as would be expected if person to person transmission was occurring in the workplace. This suggests that HPV7 is widely distributed in the community, but only causes clinical disease under specific conditions. We suggest that some unknown factor in meat enhances viral replication.
Keefe
M
M
Department of Dermatology, University of Southampton, Royal South Hants Hospital, Southampton, U.K.
al-Ghamdi
A
A
Coggon
D
D
Maitland
N J
NJ
Egger
P
P
Keefe
C J
CJ
Carey
A
A
Sanders
C M
CM
D000003:Abattoirs; D000818:Animals; D002417:Cattle; D002645:Chickens; D003132:Commerce; D004279:DNA, Viral / Q000032:analysis; D004738:Engineering; D005511:Food Handling; D006229:Hand Dermatoses / Q000209:etiology*; D006801:Humans; D008297:Male; D008460:Meat; D009784:Occupational Diseases / Q000209:etiology*; D027383:Papillomaviridae / Q000235:genetics; D030361:Papillomavirus Infections / Q000635:transmission*; D016133:Polymerase Chain Reaction; D012756:Sheep; D013552:Swine; D014412:Tumor Virus Infections / Q000382:microbiology / Q000635:transmission*; D014860:Warts / Q000635:transmission*
D004279:DNA, Viral