title: Distinguishing mixed anxiety/depression from anxiety and depressive groups using the family history method.
abstract: The relationship between anxiety and depression has long been discussed and studied. Although it appears that there are pure forms of these disorders, several investigators have suggested that there is a separate combined anxiety/depression disorder distinct from either individual disorder. Several attempts have been made to investigate this distinction using family history methods. This report compares an anxiety/depression group to a depression-only group and anxiety-only group in a veteran population (n = 71) using the family history method. The depression group was clearly differentiated from the anxiety/depression group on the variables of generalized anxiety disorder and alcohol abuse. There was also discrimination between the anxiety and anxiety/depression groups on the DSM-III-R anxious personality disorder cluster. This is the first report in this area of the literature to use standardized family history methods that include personality disorder clusters.
authors.affiliation: Department of Psychiatry, Brown University, Providence, RI.
authors.forename: J
authors.initials: J
authors.lastname: Reich
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D001008:Anxiety Disorders / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D016584:Panic Disorder / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D010554:Personality Disorders / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D010698:Phobic Disorders / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics; D012565:Schizophrenic Psychology; D014728:Veterans / Q000523:psychology*