title: Necrotizing bronchial aspergillosis in a patient with acute myelocytic leukaemia: a case report.
abstract: This case report describes a patient with acute myelocytic leukaemia, who developed a necrotizing bronchial aspergillosis. This is an uncommon, new form of invasive aspergillosis, which is mainly seen in the heart-lung transplantation setting and has only been reported once in another patient with leukaemia. Neither amphotericin B nor liposomal amphotericin (AmBisome) was effective. Only after the immune system had recovered did the infection disappear.
authors.affiliation: Department of Haematology, Dr. Daniel den Hoed Cancer Center, Rotterdam, Netherlands.
authors.forename: G J
authors.initials: GJ
authors.lastname: Creemers
authors.forename: R
authors.initials: R
authors.lastname: Slingerland
authors.forename: A
authors.initials: A
authors.lastname: Hagenbeek
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D001228:Aspergillosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D001982:Bronchial Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D001999:Bronchoscopy; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000097:blood / Q000145:classification / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D011859:Radiography
chemical_list: D000666:Amphotericin B