Effect of irradiation by semiconductor laser on responses evoked in trigeminal caudal neurons by tooth pulp stimulation.
The effect of irradiation with a gallium-aluminum-arsenide semiconductor laser on responses evoked in trigeminal subnucleus caudal neurons by tooth pulp stimulation was investigated electrophysiologically in Wistar rats anesthetized with urethane plus alpha-chloralose. The pulp of lower incisor was electrically stimulated and the evoked action potentials were extracellularly recorded in the ipsilateral caudal neurons. The laser beam was applied on the cervical surface of the stimulated incisor. The rate of firing discharges and the numbers of spikes evoked in the caudal neurons were compared before and after laser irradiation. Laser irradiation suppressed the late discharges in the response of the caudal neurons which were evoked by excitatory inputs from C-fiber afferents, but did not suppress the early discharges evoked by inputs from A delta-fiber afferents. This indicates that low power laser irradiation (semiconductor laser: 830 nm, 350 mW, CW, through the tooth structures, for 120 s) inhibited the excitation of unmyelinated fibers of the pulp without affecting fine myelinated fibers. These results suggest that low power laser irradiation has a suppressive effect on injured tissue by blocking the depolarization of C-fiber afferents.
Wakabayashi
H
H
Department of Endodontics, Showa University School of Dentistry, Tokyo, Japan.
Hamba
M
M
Matsumoto
K
K
Tachibana
H
H
D000200:Action Potentials / Q000528:radiation effects; D000818:Animals; D003782:Dental Pulp / Q000294:innervation* / Q000528:radiation effects; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000528:radiation effects; D007834:Lasers; D008297:Male; D009475:Neurons, Afferent / Q000502:physiology / Q000528:radiation effects*; D010146:Pain / Q000503:physiopathology / Q000532:radiotherapy; D051381:Rats; D017208:Rats, Wistar; D012666:Semiconductors; D014275:Trigeminal Caudal Nucleus / Q000502:physiology / Q000528:radiation effects*