title: [Isoptin-Retard 240 mg in the treatment of mild and moderate arterial hypertension].
abstract: To elucidate a hypotensive effect of isoptin-retard in a dose 240 mg/day, 17 males with mild and moderate hypertension receiving the drug underwent 24-h monitoring by SpaceLabs 5300 and pressure loading. A significant lowering of both mean systolic and diastolic pressure was found both in daytime and at night. A hypotensive effect persisted for 2 months. No case of serious cardiovascular complications, of noticeable shifts in blood biochemistry was reported.
authors.forename: G G
authors.initials: GG
authors.lastname: Arabidze
authors.forename: A N
authors.initials: AN
authors.lastname: Rogoza
authors.forename: V V
authors.initials: VV
authors.lastname: Dmitriev
authors.forename: T V
authors.initials: TV
authors.lastname: Metelitsa
authors.forename: G Iu
authors.initials: GIu
authors.lastname: Domba
authors.forename: V K
authors.initials: VK
authors.lastname: Sitina
mesh_terms: D001794:Blood Pressure / Q000187:drug effects; D015924:Blood Pressure Monitors; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D014700:Verapamil / Q000627:therapeutic use*
chemical_list: D003692:Delayed-Action Preparations; D014700:Verapamil
vernacular_title: Izoptin-retard 240 mg pri lechenii miagkoĭ i umerennoĭ arterial'noĭ gipertonii.