title: Biemnasterol, a new cytotoxic sterol with the rare 22,25-diene side chain, isolated from the marine sponge Biemna sp.
abstract: Biemnasterol [2], a new sterol with a 22,25-diene side chain possessing cytotoxic activity, has been isolated from the Okinawan marine sponge Biemna sp. and the structure elucidated on the basis of spectroscopic data and chemical means.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
authors.forename: C M
authors.initials: CM
authors.lastname: Zeng
authors.forename: M
authors.initials: M
authors.lastname: Ishibashi
authors.forename: J
authors.initials: J
authors.lastname: Kobayashi
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D007624:KB Cells / Q000187:drug effects; D007939:Leukemia L1210 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D011161:Porifera / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013261:Sterols / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D013261:Sterols; C085402:biemnasterol