[Effect of nitrobenzenes on methemoglobin formation and activity of antioxidative enzymes in mouse erythrocytes].
The mice intoxication with intraperitoneal introduction of 1,3,5-trinitrobenzene and 2,4,6-trinitrotoluene causes an increase of methemoglobin and a decrease of glutathione level. But intoxication by polynitrobenzenes exerts no effect on the total level of SH-groups. A small increase in total activity of dehydrogenases of the pentose phosphate way in response to 2,4,6-trinitrotoluene intoxication is also revealed. The level of both lipid peroxidation, superoxide dismutase and catalase activity is not influenced by 2,4,6-trinitrotoluene and 1,3,5-trinitrobenzene.
Shugaleĭ
I V
IV
Tselinskiĭ
I V
IV
L'vov
S N
SN
Baev
V I
VI
Dolmatov
V Iu
VIu
Karpenkova
I V
IV
D000818:Animals; D002374:Catalase / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects* / Q000201:enzymology; D005978:Glutathione / Q000097:blood; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008706:Methemoglobin / Q000378:metabolism*; D051379:Mice; D009578:Nitrobenzenes / Q000506:poisoning*; D010084:Oxidation-Reduction; D013482:Superoxide Dismutase / Q000187:drug effects
D009578:Nitrobenzenes; D008706:Methemoglobin; D002374:Catalase; D013482:Superoxide Dismutase; D005978:Glutathione
Vliianie nitrobenzolov na metgemoglobinoobrazovanie i aktivnost' antiokislitel'nykh fermentov éritrotsitov myshi.