title: Extramedullary plasmacytoma of the larynx.
abstract: A case of IgD myeloma in a 54-year-old male with a long-standing history of extramedullary plasmacytoma involving the larynx is reported. The patient was treated with radiation therapy and laryngectomy. Twelve years later, he complained of nasal bleeding. On examination he was found to have large masses in the left nasal cavity and in the left supraclavicular region. Histological examination of both lesions showed plasmacytoma. Serum immunoglobulin studies revealed an IgD monoclonal spike of the lambda type. Bence-Jones protein was present. Using the immunoperoxidase staining technique, cytoplasmic monoclonal IgD was detected.
authors.affiliation: Department of Otorhinolaryngology, School of Medicine, Yokohama City University, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Mochimatsu
authors.forename: M
authors.initials: M
authors.lastname: Tsukuda
authors.forename: S
authors.initials: S
authors.lastname: Sawaki
authors.forename: Y
authors.initials: Y
authors.lastname: Nakatani
mesh_terms: D001859:Bone Neoplasms / Q000276:immunology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000209:etiology*; D009669:Nose Neoplasms / Q000276:immunology; D010954:Plasmacytoma / Q000628:therapy; D013997:Time Factors