title: Adrenal hemorrhage in infants undergoing ECMO: prevalence and clinical significance.
abstract: OBJECTIVE
  To determine the prevalence and clinical significance of adrenal hemorrhage in infants undergoing ECMO therapy.
  
  
  METHODS
  Prospective US evaluation of the adrenal glands was performed in 50 consecutive infants undergoing ECMO. The infants were examined at least every other day while on bypass. Adrenal hemorrhage was diagnosed at US examination when a suprarenal mass or adrenal gland enlargement was identified.
  
  
  RESULTS
  Adrenal hemorrhage was identified in two infants (4%); one infant with septicemia, and one with primary pulmonary hypertension. Both hemorrhages were unilateral; one was right-sided, and one left-sided. One hemorrhage occurred on the first day following the onset of ECMO and the other on the third day. The adrenal hemorrhage was not associated with an acute drop in hematocrit nor with adrenal insufficiency in either infant.
  
  
  CONCLUSIONS
  Adrenal hemorrhage is uncommon in infants undergoing ECMO. When hemorrhage did occur in this series, it did not result in clinical complications.
authors.affiliation: Department of Diagnostic Imaging and Radiology, Children's National Medical Center, Washington, DC 20010.
authors.forename: C M
authors.initials: CM
authors.lastname: Sivit
authors.forename: B L
authors.initials: BL
authors.lastname: Short
authors.forename: M E
authors.initials: ME
authors.lastname: Revenis
authors.forename: L C
authors.initials: LC
authors.lastname: Rebolo
authors.forename: C
authors.initials: C
authors.lastname: Brown-Jones
authors.forename: D B
authors.initials: DB
authors.lastname: Garin
mesh_terms: D000307:Adrenal Gland Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects*; D005260:Female; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011446:Prospective Studies; D014463:Ultrasonography