title: Congenital heart block in one of the HLA identical twins.
abstract: A case of HLA identical twins with one affected by congenital heart block is reported. Both twins, as their mother, had more than 12-fold higher anti-Ro antibody titers compared to healthy controls, but no differences were observed between the affected and the healthy baby. It is possible that there is a third factor causing the manifestation of this disease.
authors.affiliation: Department of Obstetrics and Gynecology, University of Helsinki, Finland.
authors.forename: R
authors.initials: R
authors.lastname: Kaaja
authors.forename: H
authors.initials: H
authors.lastname: Julkunen
authors.forename: P
authors.initials: P
authors.lastname: Ammälä
authors.forename: P
authors.initials: P
authors.lastname: Kurki
authors.forename: S
authors.initials: S
authors.lastname: Koskimies
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D004200:Diseases in Twins; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006327:Heart Block / Q000276:immunology*; D006330:Heart Defects, Congenital / Q000276:immunology*; D006801:Humans; D011247:Pregnancy
chemical_list: D000974:Antibodies, Antinuclear; D006680:HLA Antigens; C035356:SS-A antibodies; C035357:SS-B antibodies