Synthesis, structural and biochemical characterization of cytostatic methotrexate-gamma-glutamyl-glutathione conjugates.
Kussmann
M
M
Faculty of Chemistry, University of Konstanz, Germany.
Wiehr
D
D
Knepper
T
T
Przybylski
M
M
D000818:Animals; D002645:Chickens; D005493:Folic Acid Antagonists / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D005978:Glutathione / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008099:Liver / Q000201:enzymology; D009682:Magnetic Resonance Spectroscopy; D008727:Methotrexate / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008968:Molecular Conformation; D015394:Molecular Structure; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013329:Structure-Activity Relationship
D005493:Folic Acid Antagonists; D005978:Glutathione; D008727:Methotrexate