Evaluation of the anti-arthritic activity and an alternate synthesis of a thiophene-substituted 10-deazaaminopterin.
Desai
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Department of Biochemistry, University of South Alabama Mobile 36688.
Nair
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D000818:Animals; D001169:Arthritis, Experimental / Q000188:drug therapy*; D005260:Female; D005493:Folic Acid Antagonists / Q000627:therapeutic use*; D005971:Glutamates / Q000138:chemical synthesis* / Q000627:therapeutic use*; D007202:Indicators and Reagents; D008727:Methotrexate / Q000627:therapeutic use*; D011622:Pterins / Q000138:chemical synthesis* / Q000627:therapeutic use*; D051381:Rats; D011917:Rats, Inbred Lew
D005493:Folic Acid Antagonists; D005971:Glutamates; D007202:Indicators and Reagents; C085588:N-((5-(2,4-diamino-6-pteridinyl)ethyl)-2-thenoyl)glutamic acid; D011622:Pterins; D008727:Methotrexate