title: Long-term results after surgical reduction cheiloplasty in patients with Melkersson-Rosenthal syndrome and cheilitis granulomatosa.
abstract: Cheilitis granulomatosa in patients with Melkersson-Rosenthal syndrome has proven difficult to treat, and various forms of symptomatic treatment of orofacial swellings have been used with varying success. To evaluate long-term results after surgical reduction cheiloplasty in patients suffering from persistent lip swellings, a follow-up study was performed on 13 patients after 16 years (median). The operations were performed after unsuccessful conservative treatment and regardless of disease activity. Pre- and postoperative medical histories were updated and a clinical examination evaluated the following criteria for a good result: symmetry of the lip, a normalized anterior projection, dimensional harmony between upper and lower lip, no disfiguring cicatrices, and no sensory disturbances. In spite of postoperative disease activity in 6 patients, all 13 patients were satisfied with the long-term result. Clinically, the results in 12 patients were considered good. We therefore recommend lip resection as described when a stationary swelling becomes associated with permanent aesthetic deformity or functional disturbances and conservative measures are unsuccessful.
authors.affiliation: Department of Plastic and Reconstructive Surgery, University Hospital (Rigshospitalet), Copenhagen, Denmark.
authors.forename: N
authors.initials: N
authors.lastname: Ellitsgaard
authors.forename: A P
authors.initials: AP
authors.lastname: Andersson
authors.forename: N
authors.initials: N
authors.lastname: Worsaae
authors.forename: S
authors.initials: S
authors.lastname: Medgyesi
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008046:Lip / Q000601:surgery*; D008297:Male; D008556:Melkersson-Rosenthal Syndrome / Q000601:surgery*; D008875:Middle Aged; D013518:Surgery, Plastic / Q000379:methods