Mediastinal Castleman disease: CT findings.
OBJECTIVE
Our objective was to characterize the CT findings of mediastinal Castleman disease.


METHODS
We reviewed the CT findings of mediastinal Castleman disease in 10 patients.


RESULTS
In nine cases of hyaline-vascular type Castleman disease, lymph nodes were 2-7 cm in diameter and located in the hilum in six patients, superior mediastinum in two patients, and posterior mediastinum in one patient. On CT the tumors were well-demarcated round masses showing dense homogeneous enhancement after contrast medium injection. Dynamic CT in one case showed gradual centripetal enhancement of the mass. In one case of hyaline-vascular type Castleman disease, lumpy and irregular calcifications were noted in the center of the mass. In the one case of plasma cell type Castleman disease, multiple small homogeneously enhancing nodes were found in the mediastinal and supraclavicular area.


CONCLUSIONS
CT findings may suggest the preoperative diagnosis of mediastinal Castleman disease.
Moon
W K
WK
Department of Radiology, College of Medicine, Seoul National University, Republic of Korea.
Im
J G
JG
Kim
J S
JS
Choi
C G
CG
Kim
H C
HC
Yeon
K M
KM
Han
M C
MC
D000293:Adolescent; D000328:Adult; D005871:Castleman Disease / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008477:Mediastinal Diseases / Q000000981:diagnostic imaging*; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed