[Antioxidant activity of a new derivative of 4-hydrazinoquinazoline in experimental cerebral hypoxia].
It is established that KS-79 compound possesses the high level of antioxidant activity and realizes its antioxidant effect at initial stages of free-radical hydrogen peroxide oxidation of lipids. Due to this ability it differs from the oxidants of direct-type action.
Dunaev
V V
VV
Belenichev
I F
IF
Kovalenko
S I
SI
Mazur
I A
IA
Siniak
R S
RS
Bashkin
I N
IN
Tishkin
V S
VS
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002545:Brain Ischemia / Q000188:drug therapy / Q000378:metabolism; D005609:Free Radicals; D006834:Hydrazines / Q000494:pharmacology*; D002534:Hypoxia, Brain / Q000188:drug therapy* / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D011799:Quinazolines / Q000494:pharmacology*; D052999:Quinazolinones; D051381:Rats; D017208:Rats, Wistar; D014810:Vitamin E / Q000378:metabolism
D000975:Antioxidants; D005609:Free Radicals; D006834:Hydrazines; D011799:Quinazolines; D052999:Quinazolinones; D014810:Vitamin E; C085354:4-hydrazinoquinazoline
Antioksidantnaia aktivnost'novogo proizvodnogo 4-gidrazinokhinazolina pri éksperimental'noĭ gipoksii golovnogo mozga.