Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential.
Howarth
N M
NM
Department of Medicinal Chemistry, School of Pharmacy & Pharmacology, University of Bath, Claverton Down, U.K.
Purohit
A
A
Reed
M J
MJ
Potter
B V
BV
D001943:Breast Neoplasms / Q000188:drug therapy / Q000201:enzymology; D002455:Cell Division / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D004970:Estrone / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D013429:Sulfatases / Q000037:antagonists & inhibitors*; D013451:Sulfonic Acids / Q000494:pharmacology / Q000627:therapeutic use; D014407:Tumor Cells, Cultured
D013451:Sulfonic Acids; D004970:Estrone; C005741:sulfamic acid; D013429:Sulfatases; C020121:estrone sulfatase