title: Extensive skeletal metastases from chondrosarcoma without pulmonary involvement.
abstract: Among 251 patients who presented to our orthopedic oncology unit over the last 20 years with chondrosarcoma, we identified two patients with low to intermediate grade conventional chondrosarcoma who developed multifocal bone metastases in the absence of pulmonary spread. The metastatic lesions were of a similar histologic grade to the primary site. One of the patients had synchronous foci, while the other developed the bone lesions 3 years after initial presentation. The unusual behavior of these cases, as well as the possibility that they may represent instances of multicentric chondrosarcoma, is discussed.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston 02114.
authors.forename: D G
authors.initials: DG
authors.lastname: Disler
authors.forename: A E
authors.initials: AE
authors.lastname: Rosenberg
authors.forename: D
authors.initials: D
authors.lastname: Springfield
authors.forename: J X
authors.initials: JX
authors.lastname: O'Connell
authors.forename: D I
authors.initials: DI
authors.lastname: Rosenthal
authors.forename: S V
authors.initials: SV
authors.lastname: Kattapuram
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary; D008297:Male; D011859:Radiography