title: Systemic ceroid-lipofuscinosis in a Japanese domestic cat.
abstract: An 11-month-old castrated male Japanese domestic cat was euthanized because of neurological symptoms such as shivering and difficulty of walking. Histopathological examination showed glial proliferation and marked deposition of ceroid-lipofuscin in the neuronal and glial cells of the brain. Ceroid-lipofuscin was deposited also in reticuloendothelial cells of the liver, spleen and some lymph nodes.
authors.affiliation: Department of Veterinary Pathology, Faculty of Agriculture, University of Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nakayama
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: T
authors.initials: T
authors.lastname: Shouda
authors.forename: K
authors.initials: K
authors.lastname: Uetsuka
authors.forename: N
authors.initials: N
authors.lastname: Sasaki
authors.forename: N
authors.initials: N
authors.lastname: Goto
mesh_terms: D000818:Animals; D001284:Atrophy; D001921:Brain / Q000473:pathology*; D002371:Cat Diseases; D002415:Cats; D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D008297:Male; D017628:Microglia / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009472:Neuronal Ceroid-Lipofuscinoses / Q000473:pathology / Q000662:veterinary*; D009919:Orchiectomy