Effect of aerosolised verapamil and nifedipine in bronchial asthma.
Twenty patients of bronchial asthma were given 5 mg of either nifedipine or verapamil as aerosol therapy in a randomized fashion. Both drugs showed a statistically significant improvement in FVC, PEFR at zero hours lasting through 90-120 minutes. Changes in respiratory rate, pulse rate, blood pressure were insignificant with verapamil while appreciable tachycardia and transient fall in BP occurred with nifedipine therapy.
Gupta
S
S
Department of Medicine, Lady Hardinge Medical College, New Delhi.
Meena
H S
HS
Chopra
R
R
Bidani
R
R
D000280:Administration, Inhalation; D000328:Adult; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy*; D005260:Female; D006801:Humans; D009543:Nifedipine / Q000008:administration & dosage* / Q000627:therapeutic use; D014700:Verapamil / Q000008:administration & dosage* / Q000627:therapeutic use
D000336:Aerosols; D014700:Verapamil; D009543:Nifedipine