Radiographic findings in 13q-syndrome.
Of 169 children with retinoblastoma treated at our institution between 1962 and 1993, 5 had concurrent severe mental retardation, hypotonia, and abnormalities of constitutional chromosome 13. The associated skeletal abnormalities of these 5 children are described and include delayed skeletal maturation, metaphyseal abnormalities, microcrania, facial bone abnormalities, and gracile long bones.
Kaste
S C
SC
Department of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee.
Pratt
C B
CB
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000000981:diagnostic imaging*; D025063:Chromosome Disorders; D002882:Chromosomes, Human, Pair 13; D005134:Eye Neoplasms / Q000150:complications / Q000235:genetics; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography; D012175:Retinoblastoma / Q000150:complications / Q000235:genetics; D013577:Syndrome