A case of laboratory acquired infection with Escherichia coli O157:H7.
A case of laboratory-acquired infection with Escherichia coli O157:H7 is presented. Evidence of the identity of the infecting strain was provided by toxin type and plasmid profiles. Because no obvious technical errors in laboratory practices could be demonstrated we conclude that the infecting dose for E. coli O157:H7 may be small. The clinical course was uncomplicated; during reconvalescence, the patient's serum recognized a unique 87 kDa band on immunoblots of the infecting strain.
Burnens
A P
AP
National Reference Laboratory for Foodborne Diseases, University of Berne, Switzerland.
Zbinden
R
R
Kaempf
L
L
Heinzer
I
I
Nicolet
J
J
D000907:Antibodies, Bacterial / Q000097:blood; D001426:Bacterial Proteins / Q000276:immunology; D001427:Bacterial Toxins / Q000276:immunology; D015153:Blotting, Western; D002648:Child; D003092:Colitis / Q000382:microbiology; D004797:Enzyme-Linked Immunosorbent Assay; D004926:Escherichia coli / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000276:immunology / Q000382:microbiology*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000382:microbiology; D006801:Humans; D007757:Laboratory Infection / Q000276:immunology / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D022622:Shiga Toxin 1; D022641:Shiga Toxin 2
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D022622:Shiga Toxin 1; D022641:Shiga Toxin 2