Distal renal tubular acidosis: molecular and clinical aspects.
The traditionally descriptive classification of DRTA disorders is being refined as molecular defects are identified. Diagnosis of DRTA is easy: Hyperchloremic acidosis should arouse suspicion, and confirmation can be obtained by measuring urinary pH and ammonia excretion. Treatment is also relatively straightforward and readily corrects all manifestations of the acidification defect.
Arruda
J A
JA
University of Illinois, Chicago.
Cowell
G
G
D000141:Acidosis, Renal Tubular / Q000145:classification / Q000150:complications / Q000235:genetics / Q000628:therapy / Q000652:urine; D000641:Ammonia / Q000652:urine; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007686:Kidney Tubules, Distal / Q000503:physiopathology; D008967:Molecular Biology; D017693:Sodium Bicarbonate / Q000627:therapeutic use; D016482:Urinalysis
D000641:Ammonia; D017693:Sodium Bicarbonate