title: Ultrasound monitored laser-induced local hyperthermia in the liver. An experimental study on pigs.
abstract: Ultrasound (US) was used to monitor the size of tissue necrosis generated by Nd-YAG laser-induced local interstitial hyperthermia and tissue coagulation in 8 normal pig livers. Four treatments were done in each liver with 4 different energy settings. The size of the tissue necrosis measured on specimens was compared to the size measured on US. The laser energy caused a round tissue necrosis with some charring in the centre surrounded by a zone of white necrosis and a thin border of hyperaemia. A good correlation was found between the true and US-measured size of the necrosis diameters. It therefore seems possible to safely guide and monitor local laser hyperthermia in the liver with real-time US. The water-cooled quartz fibre used in this study has, however, some limitations.
authors.affiliation: Department of Radiology, University Hospital, Uppsala, Sweden.
authors.forename: A M
authors.initials: AM
authors.lastname: Löfberg
authors.forename: D
authors.initials: D
authors.lastname: Arvidsson
authors.forename: T
authors.initials: T
authors.lastname: Andersson
authors.forename: P G
authors.initials: PG
authors.lastname: Lindgren
authors.forename: L E
authors.initials: LE
authors.lastname: Lörelius
authors.forename: H
authors.initials: H
authors.lastname: Nordlinder
mesh_terms: D000537:Aluminum Oxide; D000538:Aluminum Silicates; D000818:Animals; D005260:Female; D006358:Hot Temperature; D006979:Hyperthermia, Induced; D017075:Laser Coagulation; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D008297:Male; D009336:Necrosis; D009354:Neodymium; D013552:Swine; D014463:Ultrasonography; D015019:Yttrium
chemical_list: D000538:Aluminum Silicates; D009354:Neodymium; D015019:Yttrium; D000537:Aluminum Oxide