[Structural similarity of the active sites of major histocompatibility complex class I proteins and ubiquitin].
With the help of a new method of protein primary structures analysis, i.e. CAACRA (comparative amino acid codon root analysis) a marked structural similarity of the MHC class I protein active sites and ubiquitin alpha-helix has been revealed. Using the CAACRA a periodicity of ubiquitin primary structure has been shown. Ubiquitin molecule consists of 4 repeat units.
Chipens
G I
GI
Inkina
N M
NM
D000595:Amino Acid Sequence; D001665:Binding Sites / Q000502:physiology; D003062:Codon; D015789:HLA-A2 Antigen / Q000737:chemistry*; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary; D017386:Sequence Homology, Amino Acid; D014452:Ubiquitins / Q000737:chemistry*
D003062:Codon; D015789:HLA-A2 Antigen; D014452:Ubiquitins
Skhodstvo struktur aktivnykh tsentrov belkov glavnogo kompleksa gistosovmestimosti klassa I i ubikvitina.