[Interaction of prothrombin with erythrocytes and alveolar macrophages].
A study was made of porcine 125I-prothrombin interaction with red cells and alveolar macrophages in the presence of CaCl2 or EDTA. Prothrombin binding with red cells was similar to that to alveolar macrophages (Kd = 3.7 x 10(-6) M and 1.9 x 10(-6) M, respectively). These parameters did not depend on the presence of Ca2+ ions in the medium. Red cell hemolysis led to diminished affinity of prothrombin to blood ghost surfaces.
Kiselev
S V
SV
Khaĭrutdinova
A I
AI
Zubairov
D M
DM
D000818:Animals; D004912:Erythrocytes / Q000378:metabolism*; D016676:Macrophages, Alveolar / Q000378:metabolism*; D011516:Prothrombin / Q000378:metabolism*; D013552:Swine
D011516:Prothrombin
Vzaimodeĭstvie protrombina s éritrotsitami i al'veoliarnymi makrofagami.