title: Combination antiretroviral therapy for HIV infection.
abstract: Despite recent disappointment with antiretroviral agents, investigators continue to examine combination therapy with agents that target the same or different stages of the HIV life cycle. Initial studies suggest that when therapy is started early in the course of infection, certain combinations may be better than single-drug regimens in reducing viral burden and delaying the onset of drug resistance.
authors.affiliation: Comprehensive AIDS Program, University of Miami School of Medicine.
authors.forename: M A
authors.initials: MA
authors.lastname: Fischl
mesh_terms: D000998:Antiviral Agents / Q000145:classification / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination; D006678:HIV / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development / Q000502:physiology; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D014158:Transcription, Genetic / Q000187:drug effects; D017211:Treatment Failure; D016662:Virus Integration / Q000187:drug effects; D014779:Virus Replication / Q000187:drug effects
chemical_list: D000998:Antiviral Agents