title: Immunoblastic malignant lymphoma in adult onset Still's disease.
abstract: Lymphadenopathy commonly occurs in patients with adult onset Still's disease (AOSD). Besides the more common reactive hyperplasia, the histological pattern may occasionally be confused with that of malignant lymphoma. A case of AOSD that developed an immunoblastic malignant lymphoma is described. Immunohistochemistry showed the B cell nature of the proliferating cells. As a result, AOSD should be added to the list of systemic rheumatic diseases, the course of which may be complicated by lymphoproliferative malignancies. Our case underlines the need for a careful examination and of close followup to detect this eventuality earlier.
authors.affiliation: Division of Rheumatology, Hospital of Ferrara, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Trotta
authors.forename: L
authors.initials: L
authors.lastname: Dovigo
authors.forename: G
authors.initials: G
authors.lastname: Scapoli
authors.forename: L
authors.initials: L
authors.lastname: Cavazzini
authors.forename: G
authors.initials: G
authors.lastname: Castoldi
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000473:pathology; D016706:Still's Disease, Adult-Onset / Q000150:complications*