title: Endocarditis caused by Kingella denitrificans.
abstract: We report the case of a 48-year-old man with native valve endocarditis caused by Kingella denitrificans. He was successfully treated with a combination of beta-lactam antibiotics and aminoglycosides, after which he underwent valve replacement surgery. This case represents the first report in the literature of elective native valve replacement. Previously reported cases are discussed together with management options, including suggestions for the treatment of patients with beta-lactam allergy and those infected with beta-lactamase producing strains.
authors.affiliation: Department of Microbiology, Bristol Royal Infirmary, U.K.
authors.forename: I J
authors.initials: IJ
authors.lastname: Hassan
authors.forename: L
authors.initials: L
authors.lastname: Hayek
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D006350:Heart Valve Prosthesis; D006801:Humans; D017881:Kingella / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D016870:Neisseriaceae Infections / Q000188:drug therapy / Q000382:microbiology*; D001618:beta-Lactamases / Q000096:biosynthesis; D047090:beta-Lactams
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D001618:beta-Lactamases