[A simultaneous determination of honokiol and mangolol in Oriental pharmaceutical decoctions containing magnolia bark by ion-pair high-performance liquid chromatography. II].
A simple method using ion-pair high-performance liquid chromatography was established for the rapid and precise determination of honokiol(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol) and magnolol(5,5'-di-2-propenyl-1,1'-biphenyl-2,2'-diol) in eighteen species of oriental pharmaceutical decoctions containing Magnolia bark. An ODS column and a mixed solvent system of water involving 10 mM tetra-n-amyl-ammonium bromide (TAA) and acetonitrile (4:6) as a mobile phase were used for the separation. Honokiol and magnolol were eluted without interference of other coexisting components within 12 min.
Ueda
J
J
Tohoku College of Pharmacy, Miyagi, Japan.
Asaka
N
N
Tanaka
I
I
Hayashi
Y
Y
Hirose
Y
Y
Momma
N
N
Yasuda
T
T
Ohsawa
K
K
D001713:Biphenyl Compounds / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D017705:Lignans; D000498:Allyl Compounds; D010636:Phenols
D001713:Biphenyl Compounds; D004365:Drugs, Chinese Herbal; D017705:Lignans; C005498:magnolol; C005499:honokiol; D000498:Allyl Compounds; D010636:Phenols