title: Effect of androgen treatment on fear reactions in ewes.
abstract: The effects of prolonged androgen treatment (testosterone propionate, 10 mg/day for 56 days) on fear reactions in ewes were studied using a battery of tests previously designed and validated. These tests involved situations classically reported to induce fear in sheep: isolation from conspecifics, surprise, and presence of a human. Testosterone-treated ewes differed from controls in a number of behavioral characteristics which indicate that they are less fearful in the various test situations. Their overall scores were respectively 9.5 vs 11.5 (P < 0.05) in the isolation test, 7.9 vs 13.1 (P < 0.001) in the surprise test, and 7.8 vs 13.2 (P < 0.001) in the human test. Testosterone treatment thus clearly reduces fear reactions in ewes subjected to nonsocial situations that are typically fear-eliciting.
authors.affiliation: Laboratoire d'Etude du Comportement Animal, I.N.R.A. Centre de Tours-Nouzilly, France.
authors.forename: M
authors.initials: M
authors.lastname: Vandenheede
authors.forename: M F
authors.initials: MF
authors.lastname: Bouissou
mesh_terms: D000818:Animals; D001143:Arousal / Q000187:drug effects*; D005239:Fear / Q000187:drug effects*; D005260:Female; D006185:Habituation, Psychophysiologic / Q000187:drug effects; D010052:Ovariectomy; D011930:Reaction Time / Q000187:drug effects; D012756:Sheep; D012931:Social Environment; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D013739:Testosterone