title: A significant percentage of normal T lymphocytes express HLA-DP in the peripheral blood.
abstract: HLA-DP expression has been widely investigated on T lymphocytes activated under different conditions. In the present study, a double staining procedure was used in flow cytometric experiments to define DP expression on normal peripheral blood T lymphocytes. In about two-thirds of the case analyzed, DP was expressed on a higher percentage of normal peripheral T lymphocytes than DR was. This was particularly true for 1 of the 16 cases investigated in which the percentage of T lymphocytes expressing DP was 46% and in which DP expression was mainly the prerogative of CD8+ and CD56+ lymphocytes.
authors.affiliation: Centre Régional de Transfusion Sanguine, Strasbourg, France.
authors.forename: C
authors.initials: C
authors.lastname: Baudeau
authors.forename: A
authors.initials: A
authors.lastname: Falkenrodt
authors.forename: A
authors.initials: A
authors.lastname: Parissiadis
authors.forename: M M
authors.initials: MM
authors.lastname: Tongio
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D015415:Biomarkers; D005260:Female; D005434:Flow Cytometry; D005455:Fluorescent Antibody Technique; D006682:HLA-DP Antigens / Q000096:biosynthesis / Q000097:blood*; D006684:HLA-DR Antigens / Q000097:blood; D006801:Humans; D016130:Immunophenotyping; D008213:Lymphocyte Activation; D008297:Male; D016176:T-Lymphocyte Subsets / Q000378:metabolism*
chemical_list: D015703:Antigens, CD; D015415:Biomarkers; D006682:HLA-DP Antigens; D006684:HLA-DR Antigens