Disseminated measles infection after vaccination in a child with a congenital immunodeficiency.
An infant boy with a congenital immunodeficiency had fatal disseminated measles after administration of a live attenuated measles vaccine. This rare complication was confirmed with molecular virologic techniques. Although efforts to expand availability of vaccinations are critically important, caution is warranted in children with potentially severe immunologic dysfunction.
Monafo
W J
WJ
Department of Pediatrics, Washington University Medical Center, St. Louis, Missouri.
Haslam
D B
DB
Roberts
R L
RL
Zaki
S R
SR
Bellini
W J
WJ
Coffin
C M
CM
D005183:Failure to Thrive / Q000209:etiology; D006801:Humans; D007223:Infant; D008297:Male; D008457:Measles / Q000209:etiology* / Q000473:pathology; D008458:Measles Vaccine / Q000009:adverse effects*; D016511:Severe Combined Immunodeficiency / Q000150:complications*; D014613:Vaccines, Attenuated / Q000009:adverse effects
D008458:Measles Vaccine; D014613:Vaccines, Attenuated