title: The relationship between endoscopic findings of gastric ulcer scar and ulcer relapse.
abstract: Regenerated mucosal patterns that appeared during the healing of chronic gastric ulcers were observed and assessed in detail by magnifying endoscopes. Three patterns of ulcer scarring were distinguished: Sa with central depression, Sb with a coarse regenerated mucosal pattern, and Sc with a fine mucosal pattern. From a study on the relationship between the depth of ulcer confirmed histologically and the endoscopic findings of the scar, a clear distinction could be made endoscopically between U1-IV scar with a well-demarcated scarring zone, U1-III scar with an unclear boundary, and U1-II scar without a distinct scar area. Scar patterns were also related to ulcer depth. Analysis of the relationship between an ulcer relapse and the scar pattern demonstrated that the ulcer relapse rate over a 2-year follow-up period was 84% in Sa, 33% in Sb, and 0% in Sc.
authors.affiliation: Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Sakaki
authors.forename: T
authors.initials: T
authors.lastname: Takemoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015738:Famotidine / Q000627:therapeutic use; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole / Q000627:therapeutic use; D012008:Recurrence; D013276:Stomach Ulcer / Q000188:drug therapy / Q000473:pathology*; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology*
chemical_list: D015738:Famotidine; D009853:Omeprazole