Annetocin: an oxytocin-related peptide isolated from the earthworm, Eisenia foetida.
An oxytocin-vasopressin-related peptide, Cys-Phe-Val-Arg-Asn-Cys-Pro-Thr-Gly-NH2, was isolated from the lumbricid earthworm, Eisenia foetida and termed annectocin. Annetocin potentiated not only spontaneous contractions of the gut but also pulsatory contractions and bladder-shaking movement of the nephridia. Annetocin may be involved in osmoregulation of the animal through nephridial function.
Oumi
T
T
Faculty of Science, Hiroshima University, Japan.
Ukena
K
K
Matsushima
O
O
Ikeda
T
T
Fujita
T
T
Minakata
H
H
Nomoto
K
K
D000595:Amino Acid Sequence; D000818:Animals; D001681:Biological Assay; D002851:Chromatography, High Pressure Liquid; D007447:Invertebrate Hormones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008969:Molecular Sequence Data; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D009835:Oligochaeta / Q000502:physiology*; D010121:Oxytocin / Q000737:chemistry*; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D017386:Sequence Homology, Amino Acid
D007447:Invertebrate Hormones; D010456:Peptides, Cyclic; C085335:annetocin; D010121:Oxytocin