title: Solubility and stability of sterigmatocystin in different organic solvents.
abstract: In the present work we studied the solubility of sterigmatocystin (ST) in different organic solvents and the stability of these solutions during cold and frozen storage. ST was more soluble in chloroform and in pyridine. In cold storage ST was more stable in chloroform after both 7 and 30 days. In pyridine, ST was stable on day 7 but not on day 30. In frozen storage, 90% recovery was achieved only in chloroform. We conclude that chloroform is the most suitable organic solvent of those studied to solubilize and store standard solutions of ST.
authors.affiliation: Departamento Patología Animal I (Sanidad Animal), Facultad de Veterinaria, Universidad Complutense, Madrid, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Septien
authors.forename: M T
authors.initials: MT
authors.lastname: Cutuli
authors.forename: M E
authors.initials: ME
authors.lastname: Garcia
authors.forename: G
authors.initials: G
authors.lastname: Suarez
authors.forename: J L
authors.initials: JL
authors.lastname: Blanco
mesh_terms: D004355:Drug Stability; D012995:Solubility; D012997:Solvents; D013241:Sterigmatocystin / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D012997:Solvents; D013241:Sterigmatocystin