title: Antitumor efficacy of classical non-polyglutamylatable antifolates that inhibit dihydrofolate reductase.
authors.affiliation: University of South Alabama, Mobile 36688.
authors.forename: A
authors.initials: A
authors.lastname: Abraham
authors.forename: M G
authors.initials: MG
authors.lastname: Nair
authors.forename: J J
authors.initials: JJ
authors.lastname: McGuire
authors.forename: J
authors.initials: J
authors.lastname: Galivan
authors.forename: R L
authors.initials: RL
authors.lastname: Kisliuk
authors.forename: B R
authors.initials: BR
authors.lastname: Vishnuvajjala
mesh_terms: D000630:Aminopterin / Q000031:analogs & derivatives* / Q000627:therapeutic use / Q000633:toxicity; D000818:Animals; D000970:Antineoplastic Agents / Q000633:toxicity*; D004354:Drug Screening Assays, Antitumor; D005493:Folic Acid Antagonists / Q000633:toxicity*; D006801:Humans; D007939:Leukemia L1210 / Q000188:drug therapy; D007941:Leukemia P388 / Q000188:drug therapy; D008727:Methotrexate / Q000627:therapeutic use / Q000633:toxicity*; D051379:Mice; D008815:Mice, Inbred Strains; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D005493:Folic Acid Antagonists; C085593:gamma-methylene-10-deazaaminopterin; C085594:gamma-methylene-10-ethyl-10-deazaaminopterin; D000630:Aminopterin; D008727:Methotrexate