title: A study of structure and degradation of nonpolymeric biomaterials implanted in bone using reflected and transmitted light microscopy.
abstract: Orthopedic biomaterials currently are made of metal alloy coated with one or more thin layers of dense or porous ceramic or metal. Sections of these materials implanted in human bone were made without altering the implant or bone-implant interfaces. Bone containing an implant was fixed and then embedded in polymethylmethacrylate. Thick sections were made using a cooled, low speed diamond saw, then ground and polished. Some were stained by fuchsin-toluidine staining solution, others were acid etched to reveal the structure of the metal contained in the prosthesis. Observation by reflected and transmitted light microscopy revealed microstructure of the implant material as well as features of the surrounding tissues.
authors.affiliation: Physical Metallurgy Department, National School of Chemistry of Tolouse, France.
authors.forename: P
authors.initials: P
authors.lastname: Frayssinet
authors.forename: F
authors.initials: F
authors.lastname: Tourenne
authors.forename: I
authors.initials: I
authors.lastname: Primout
authors.forename: C
authors.initials: C
authors.lastname: Delga
authors.forename: E
authors.initials: E
authors.lastname: Sergent
authors.forename: C
authors.initials: C
authors.lastname: Besse
authors.forename: P
authors.initials: P
authors.lastname: Conte
authors.forename: A
authors.initials: A
authors.lastname: Guilhem
mesh_terms: D000497:Alloys; D001672:Biocompatible Materials / Q000737:chemistry* / Q000378:metabolism; D001842:Bone and Bones / Q000166:cytology* / Q000378:metabolism; D017886:Durapatite; D006801:Humans; D008768:Methylmethacrylates; D008853:Microscopy / Q000379:methods; D019736:Prostheses and Implants; D016610:Tissue Embedding; D014025:Titanium / Q000737:chemistry
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D008768:Methylmethacrylates; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium