Coagulation disorders in patients with monoclonal gammopathies.
Monoclonal gammopathies can present as disorders of coagulation whether the gammopathy is due to a malignant B-cell lymphoproliferative disorder or a monoclonal gammopathy of undetermined significance. Detection of the monoclonal gammopathy involves quantification of immunoglobulins including kappa and lambda along with high-resolution electrophoresis of serum. Immunofixation is occasionally needed on serum and always needed on urine for the final diagnosis.
Keren
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Warde Medical Laboratory, Ann Arbor, Michigan.
D001778:Blood Coagulation Disorders / Q000209:etiology*; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis
D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains; D016682:Lupus Coagulation Inhibitor