Treatment of cocaine abuse with monoamine oxidase inhibitors.
A cocaine-abusing patient was treated with phenelzine and tranylcypromine, under supervision, as deterrent drugs; other medical and psychological treatments had failed. When he eventually risked using cocaine there was no hypertensive reaction. Nevertheless, the deterrent effect seemed helpful in breaking his pattern of cocaine use, as confirmed by hair analysis for cocaine.
Brewer
C
C
Stapleford Centre, London.
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D003042:Cocaine / Q000009:adverse effects; D006801:Humans; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D010624:Phenelzine / Q000009:adverse effects / Q000627:therapeutic use; D015813:Substance Abuse Detection; D019966:Substance-Related Disorders / Q000523:psychology / Q000534:rehabilitation*; D014191:Tranylcypromine / Q000009:adverse effects / Q000627:therapeutic use
D008996:Monoamine Oxidase Inhibitors; D014191:Tranylcypromine; D003042:Cocaine; D010624:Phenelzine