title: [Arteriosclerosis obliterans and ozone therapy. Its administration by different routes].
abstract: We report 72 non-diabetic patients with obliterant atherosclerosis, stadium II, (intermittent claudication). The medium age of these patients was 62 +/- 4.5 years old. They were randomly included into four groups. Three were treated with Ozone: one of them by endovenous way, other intramuscular way, and the last one by rectal way; meanwhile, in the fourth group the patients were submitted to conventional medical treatment (control group). In the three ozone-groups there weren't differences when they were compared between then. But there was a significant improvement in comparison with the control group. The claudication distance in the treadmill increased to the 2.5 km/hour. Ankle/arm pressure rates hadn't significant differences, this corroborates the ozone action on the microcirculation. The least uncomfortable, the more harmless and the more economic way was the rectal way.
authors.affiliation: Instituto de Angiología y Cirugía Vascular, La Habana, Cuba.
authors.forename: A
authors.initials: A
authors.lastname: Romero Valdés
authors.forename: R
authors.initials: R
authors.lastname: Blanco González
authors.forename: S
authors.initials: S
authors.lastname: Menéndez Cepero
authors.forename: M
authors.initials: M
authors.lastname: Gómez Moraleda
authors.forename: J
authors.initials: J
authors.lastname: Ley Pozo
mesh_terms: D001162:Arteriosclerosis Obliterans / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007383:Intermittent Claudication / Q000188:drug therapy / Q000503:physiopathology; D008875:Middle Aged; D010126:Ozone / Q000008:administration & dosage*; D012074:Remission Induction
chemical_list: D010126:Ozone
vernacular_title: Ateroesclerosis obliterante y ozonoterapia. Administración por diferentes vías.