Topical pharmacotherapy for allergic rhinitis: nedocromil.
Nedocromil sodium is a mast-cell stabilizer that prevents or ablates both the acute and late phases of the allergic response. It is an antiinflammatory agent that is not a steroid. It is more potent than the currently available mast-cell stabilizer, cromolyn, and maintenance therapy may be possible at less frequent intervals than the initially recommended regimen of 4 times daily. Nedocromil for pulmonary administration is currently available. The nasal form has undergone clinical trials but has not yet been released in the United States.
Mabry
R L
RL
Department of Otolaryngology, University of Texas Southwestern Medical Center, Dallas 75235-9035.
D000281:Administration, Intranasal; D000336:Aerosols; D006801:Humans; D017835:Nedocromil / Q000008:administration & dosage* / Q000627:therapeutic use; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*
D000336:Aerosols; D017835:Nedocromil