title: Meningitis due to penicillin resistant Streptococcus pneumoniae occurring in a patient on long term ampicillin prophylaxis.
abstract: A patient with persistent dural fistula, CSF rhinorrhoea and a history of recurrent bacterial meningitis developed meningitis with a penicillin-resistant strain of Streptococcus pneumoniae while on prophylactic ampicillin. The microbiological aspects of management are discussed.
authors.affiliation: Department of Microbiology, Hope Hospital, Salford, U.K.
authors.forename: P R
authors.initials: PR
authors.lastname: Chadwick
authors.forename: M G
authors.initials: MG
authors.lastname: Keaney
authors.forename: R A
authors.initials: RA
authors.lastname: Jones
mesh_terms: D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use*; D006259:Craniocerebral Trauma / Q000150:complications; D005260:Female; D006801:Humans; D008586:Meningitis, Pneumococcal / Q000382:microbiology* / Q000517:prevention & control; D010403:Penicillin Resistance; D013296:Streptococcus pneumoniae / Q000187:drug effects*; D013997:Time Factors
chemical_list: D000667:Ampicillin