Spermatogenesis and hormone levels in rhesus macaques inoculated with simian immunodeficiency virus.
The presence of sperm in testicular tissue of rhesus macaques that died as a result of infection with simian immunodeficiency virus (SIV) was related to age and body weight. Depressed testosterone levels were not associated with elevated LH levels. The data suggest that azoospermia in the SIV-infected macaques was due to cachexia and not a direct effect of virus on the testis, supporting a similar hypothesis regarding azoospermia in men infected with human immunodeficiency virus.
Nadler
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RD
Yerkes Regional Primate Research Center, Emory University, Atlanta, GA 30322.
Manocha
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AD
McClure
H M
HM
D000367:Age Factors; D000818:Animals; D002100:Cachexia / Q000209:etiology / Q000503:physiopathology / Q000662:veterinary; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives / Q000097:blood; D019314:Dehydroepiandrosterone Sulfate; D007986:Luteinizing Hormone / Q000097:blood; D008253:Macaca mulatta / Q000382:microbiology / Q000502:physiology*; D008297:Male; D008992:Monkey Diseases / Q000209:etiology / Q000503:physiopathology; D016097:Simian Acquired Immunodeficiency Syndrome / Q000150:complications / Q000503:physiopathology*; D013091:Spermatogenesis / Q000502:physiology*; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D003687:Dehydroepiandrosterone; D019314:Dehydroepiandrosterone Sulfate; D007986:Luteinizing Hormone