Up-regulated transport of methotrexate and 5-methyl-tetrahydrofolate in a human breast cancer cell line.
Mandelbaum-Shavit
F
F
Department of Bacteriology, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
D001692:Biological Transport; D001943:Breast Neoplasms / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002999:Clone Cells; D005260:Female; D058973:Folate Receptors, GPI-Anchored; D006801:Humans; D007700:Kinetics; D008727:Methotrexate / Q000378:metabolism* / Q000633:toxicity*; D011956:Receptors, Cell Surface / Q000378:metabolism; D013763:Tetrahydrofolates / Q000378:metabolism*; D014407:Tumor Cells, Cultured; D015854:Up-Regulation
D002352:Carrier Proteins; D058973:Folate Receptors, GPI-Anchored; D011956:Receptors, Cell Surface; D013763:Tetrahydrofolates; C005984:5-methyltetrahydrofolate; D008727:Methotrexate