[Lipid peroxidation in experimental glaucoma and the possibilities for its correction (preliminary report)].
Lipid peroxidation products and intraocular pressure were measured in 10 rabbits with adrenalin-induced glaucoma, and the possibility of correcting these parameters with a bioantioxidant was tested. Intraocular pressure and levels of lipid peroxidation products in rabbit blood sera were found to grow in the course of adrenalin injections. Intraocular pressure significantly reduced and lipid peroxidation normalized after subconjunctival administration of a bioantioxidant.
Alekseev
V N
VN
Ketlinskiĭ
S A
SA
Sharonov
B P
BP
Martynova
E B
EB
Lauta
V F
VF
D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage; D004353:Drug Evaluation, Preclinical; D004837:Epinephrine; D005901:Glaucoma / Q000097:blood* / Q000139:chemically induced / Q000188:drug therapy; D007429:Intraocular Pressure / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects; D008315:Malondialdehyde / Q000097:blood; D011817:Rabbits; D013997:Time Factors
D000975:Antioxidants; D008315:Malondialdehyde; D004837:Epinephrine
Perekisnoe okislenie lipidov pri éksperimental'noĭ glaukome i vozmozhnosti ego korrektsii (predvaritel'noe soobshchenie).