title: Comparison of the automated random access immunoassay analysers, ACS-180 (Ciba Corning) and AIA-1200 (Tosoh).
abstract: Two random access immunoassay analysers, the ACS-180 (Ciba Corning) and the AIA-1200 (Tosoh Corp.) were compared with respect to performance and user-friendliness. Precision studies revealed an almost equal intra-assay variation coefficient, but day-to-day reproducibility was better on the AIA-1200. Recovery of dilution series of tumour markers was too high with the ACS-180. Both systems were free from carry-over effects, on account of the extra wash step in the ACS-180 (for thyrotropin, carcinoembryonic antigen and human chorionic gonadotropin) and the separate pipetting tip in the AIA-1200. Reagent stability is better in the AIA-1200 than in the ACS-180. The AIA-1200 is more user-friendly and produces a higher throughput than the ACS-180 in daily routine operation (92 results/hour vs. 78 results/hour).
authors.affiliation: Dept. Clinical Chemistry, Maaslandziekenhuis, Sittard, The Netherlands.
authors.forename: G M
authors.initials: GM
authors.lastname: Costongs
authors.forename: P C
authors.initials: PC
authors.lastname: Janson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001774:Blood Chemical Analysis / Q000295:instrumentation*; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity