Determination of captopril in pharmaceutical samples by flow injection analysis.
A flow injection spectrophotometric method for the determination of captopril involving measurement of the absorbance of the captopril complex with palladium(II) in a 0.12 M HCl medium at 400 nm is presented. The calibration graph was linear over the range 2 x 10(-5)-6 x 10(-4) M. The sampling frequency was 90 h-1 with sample injections of 70 microliters. The proposed method was applied to the determination of captopril in pharmaceutical samples.
Albero
M I
MI
Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain.
Sánchez-Petreño
C
C
García
M S
MS
Ródenas
V
V
D002216:Captopril / Q000032:analysis*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D017022:Flow Injection Analysis; D010165:Palladium / Q000032:analysis
D010165:Palladium; D002216:Captopril