title: [MR evaluation of common femoral arterial flow: age-related changes and characteristics in obstructive arterial disease of lower extremities].
abstract: Flow velocity measurements of the common femoral arteries in 60 lower extremities of 30 healthy subjects and 12 lower extremities of 7 patients with arteriosclerosis obliterans (ASO) were performed by means of magnetic resonance imaging with a use of presaturation bolus tracking (PBT) method. Our PBT method can provide both precise determination of flow velocity and evaluation of flow patterns within 30 minutes in the clinical setting. In phantom study, MR flow velocity had good correlation with actual flow velocity (r = 0.997). 30 healthy volunteers were classified into three groups; group I (20-40 years), group II (41-60 years) and group III (61-80 years). Starting time of acceleration (STA) were shortened as the age progressed. Peak reverse velocity (PRV), maximum deceleration rate (MDR), peak forward velocity/mean velocity ratio (PFV/MV) and pulsatility index (PI) were significantly decreased in group III as compared to group I and group II. Although intraluminal flow profile showed almost uniform during acceleration time on MR images, flow profile became disproportioned and reverse flow was observed in the medial portion during deceleration time. These characteristic hemodynamics were recognized in all healthy subjects regardless to the different age group. In ASO, STA was prolonged and PFV, PRV, Maximum acceleration rate, MDR, PFV/MV, PI, Vascular sectional area, flow volume were significantly decreased (p < 0.001) as compared to the control healthy group III. As the result we obtained marked characteristics such as flattening of curves and disappearance of reverse flow in MR flow waveform. On MR images, disproportion of intraluminal flow profile, decreased flow velocities during acceleration time and disappearance of reverse flow (11 of 12 extremities) during deceleration time were observed.
authors.affiliation: Department of Radiology, Toyama Medical and Pharmaceutical University.
authors.forename: K
authors.initials: K
authors.lastname: Nomura
authors.forename: R
authors.initials: R
authors.lastname: Futatsuya
authors.forename: H
authors.initials: H
authors.lastname: Seto
authors.forename: T
authors.initials: T
authors.lastname: Kamei
authors.forename: M
authors.initials: M
authors.lastname: Kakishita
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D001157:Arterial Occlusive Diseases / Q000503:physiopathology*; D001783:Blood Flow Velocity; D005263:Femoral Artery / Q000503:physiopathology*; D006801:Humans; D007866:Leg / Q000098:blood supply; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D008961:Models, Structural