title: Nutrition support after total laryngectomy.
abstract: This study was performed to evaluate the influence of different nutrition supports (enteral vs parenteral) on nutritional status, postoperative complications, and length of hospitalization in patients undergoing total laryngectomy. Forty-eight patients were divided at random into two groups and received enteral nutrition support by percutaneous endoscopic gastrostomy with a casein and soy-based polymeric formula blended with a modular protein (group A) or a balanced formula in total parenteral nutrition given through a subclavian venous catheter (group B). The results show a satisfactory preservation of nutritional status after total laryngectomy and no significant differences in the nutritional parameters between groups fed enterally or parenterally; however, percutaneous endoscopic gastrostomy could avoid many problems related to enteral nutrition support for patients undergoing laryngectomy. This route of administration was well tolerated by all the patients and, moreover, the percutaneous endoscopic gastrostomy-related complications were clinically less significant than those associated with total parenteral nutrition; this fact could explain the longer hospitalization for group B (34 +/- 11 vs 26 +/- 11 days) (p < .05).
authors.affiliation: Department of Anesthesiology and Intensive Care, University of L'Aquila, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Iovinelli
authors.forename: I
authors.initials: I
authors.lastname: Marsili
authors.forename: G
authors.initials: G
authors.lastname: Varrassi
mesh_terms: D000368:Aged; D002405:Catheterization, Central Venous / Q000009:adverse effects; D004750:Enteral Nutrition / Q000379:methods; D005069:Evaluation Studies as Topic; D005260:Female; D005774:Gastrostomy / Q000009:adverse effects; D006801:Humans; D007825:Laryngectomy; D007902:Length of Stay; D007958:Leukocyte Count; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D010288:Parenteral Nutrition / Q000379:methods; D011183:Postoperative Complications; D011184:Postoperative Period; D012709:Serum Albumin / Q000032:analysis; D012885:Skinfold Thickness; D014168:Transferrin / Q000032:analysis
chemical_list: D012709:Serum Albumin; D014168:Transferrin