Synthesis and physicochemical study (pka, logP) of some new thiazole derivatives with probable local anaesthetic activity.
Sotiropoulou
E
E
Department of Pharmaceutical Chemistry, School of Pharmacy, University of Thessaloniki, Greece.
Geronikaki
A
A
Kourounakis
P N
PN
D000779:Anesthetics, Local / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D001001:Anura; D002599:Chalcone / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012584:Sciatic Nerve / Q000187:drug effects; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000779:Anesthetics, Local; D013844:Thiazoles; D002599:Chalcone