[Effect of riboxine on mice resistance to long-term gamma-irradiation in non-lethal dose].
In experiments with mice subjected to long-term irradiation with a non-lethal dose of 4 Gy, (0.017 Gy/min), it has been shown that the number of chromosome aberrations in myelocaryocytes is reduced, the cell precursors pool in the bone marrow and the germinative epithelium are unchanged, the number of lipid radiotoxins decreases, and cell membranes are stabilized after a single dose of a purine nucleoside, riboxine (150 mg/kg, 12 h prior to irradiation).
Legeza
V I
VI
Abdul IuA
Antushevich
A E
AE
Vasiléva
T P
TP
Deev
S P
SP
Petkevich
N V
NV
Fomina
G S
GS
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000528:radiation effects; D002869:Chromosome Aberrations; D005720:Gamma Rays; D007288:Inosine / Q000494:pharmacology*; D007962:Leukocytes / Q000187:drug effects* / Q000528:radiation effects; D051379:Mice; D009504:Neutrophils / Q000187:drug effects* / Q000528:radiation effects; D011829:Radiation Dosage; D011836:Radiation Tolerance / Q000187:drug effects*; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D013997:Time Factors
D011837:Radiation-Protective Agents; D007288:Inosine
Vliianie riboksina na rezistentnost mysheĭ k prolongirovannomu gamma-oblucheniiu v neletalńoĭ doze.