Fish-oil supplementation reduces intestinal hyperproliferation in persons at risk for colon cancer.
Hyperproliferation in the upper compartments of colonic crypts is associated with an increased risk for colon cancer. A recent short-term, double-blind, placebo-controlled study found that fish-oil supplementation (8 g/day) reduced the rate of proliferation in the upper crypt cells of patients with a history of colonic polyps.
D002455:Cell Division / Q000187:drug effects*; D002986:Clinical Trials as Topic; D003110:Colonic Neoplasms / Q000473:pathology / Q000517:prevention & control*; D003111:Colonic Polyps / Q000473:pathology*; D005395:Fish Oils / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007422:Intestines / Q000473:pathology*; D012307:Risk Factors
D005395:Fish Oils