Myasthenia gravis associated with small-cell carcinoma of the lung.
A 49-year-old man complained of a 3-month history of progressive generalized muscle weakness. He was diagnosed as having small-cell lung carcinoma at the same time. He received an intravenous injection of edrophonium chloride with remarkable improvement of muscle strength. Electromyographic studies revealed a compound muscle action potential that decreased after repetitive stimulation. These findings were considered representative of myasthenia gravis (MG), and inconsistent with Eaton-Lambert syndrome. The appearance of MG with small-cell lung carcinoma seems to be very rare, but possible.
Fujita
J
J
First Department of Internal Medicine, Kagawa Medical School, Japan.
Yamadori
I
I
Yamaji
Y
Y
Yamagishi
Y
Y
Takigawa
K
K
Takahara
J
J
D018288:Carcinoma, Small Cell / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications*