title: Enzootic intranasal tumour of goats in Italy.
abstract: An outbreak of enzootic intranasal tumour (EIT) in a goat herd in Central Italy is described. From October 1990 to September 1992 41 tumors were diagnosed in goats ranging in age from 6 months to 6 years and of both the Alpine and Saanen breeds. Clinically the affected goats showed nasal discharge, facial swelling, sneezing and snoring respiration and weight loss. Post-mortem examinations revealed uni- or bilateral tumours of the olfactory mucous membrane. The neoplasms were classified as low grade adenocarcinomas. Ultrastructurally, retrovirus-like particles were observed in 10/10 tumours examined. Epidemiological and ultrastructural findings strongly suggest a viral aetiology for intranasal enzootic adenocarcinoma in the goats examined.
authors.affiliation: Istituto di Patologia Generale ed Anatomia Patologica Veterinaria, Facoltà di Medicina Veterinaria, Università di Perugia, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Vitellozzi
authors.forename: L
authors.initials: L
authors.lastname: Mughetti
authors.forename: M
authors.initials: M
authors.lastname: Palmarini
authors.forename: M T
authors.initials: MT
authors.lastname: Mandara
authors.forename: L
authors.initials: L
authors.lastname: Mechelli
authors.forename: J M
authors.initials: JM
authors.lastname: Sharp
authors.forename: I
authors.initials: I
authors.lastname: Manocchio
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000662:veterinary*; D000818:Animals; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D015511:Goat Diseases / Q000453:epidemiology*; D006041:Goats; D007558:Italy / Q000453:epidemiology; D008297:Male; D009669:Nose Neoplasms / Q000453:epidemiology / Q000662:veterinary*; D009831:Olfactory Mucosa; D012192:Retroviridae Infections / Q000453:epidemiology / Q000662:veterinary; D014412:Tumor Virus Infections / Q000453:epidemiology / Q000662:veterinary