Influence of phospholipid liposomes (PLL) on UVB-induced erythema formation.
Application of liposomal phospholipids (Natipide II) caused a significant decrease in erythema induced by UVB (280-312 mm) in patients with skin types II and III (n = 31). In accordance with findings in other organs, e.g. liver, the present findings suggest that phospholipids are capable of reducing H2O2 formation and/or increasing glutathione synthesis in human skin, thus reducing erythema formation by preventing oxidative stress.
Thiele
B
B
Department of Dermatology and Venereology, Medical University of Lübeck, Germany.
Ghyczy
M
M
Lunow
C
C
Teichert
H M
HM
Wolff
H H
HH
D000328:Adult; D004890:Erythema / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000627:therapeutic use*; D014466:Ultraviolet Rays
D010743:Phospholipids