Myasthenia gravis.
The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.
Willcox
N
N
Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
D000818:Animals; D001323:Autoantibodies / Q000276:immunology; D006801:Humans; D006965:Hyperplasia / Q000276:immunology; D007167:Immunotherapy; D009157:Myasthenia Gravis / Q000235:genetics / Q000276:immunology* / Q000628:therapy; D011950:Receptors, Cholinergic / Q000276:immunology; D013945:Thymoma / Q000276:immunology; D013950:Thymus Gland / Q000473:pathology; D013953:Thymus Neoplasms / Q000276:immunology
D001323:Autoantibodies; D011950:Receptors, Cholinergic