title: Comparison of oxygenation measurements in pediatric patients during sickle cell crises.
abstract: Measurements of the saturation of arterial blood with oxygen (SaO2) were compared in 24 children during sickle cell crises. Simultaneous pulse oximetry (Nellcor N-100 pulse oximeter) and arterial blood analysis showed that SaO2 measured by pulse oximetry overestimated cooximeter-measured SaO2 (mean bias, 6.9%; p < 0.001). The blood gas machine-calculated SaO2 also overestimated cooximeter-measured SaO2 (p < 0.001). The bias increased with increasing age (p = 0.002) and carboxyhemoglobin level (p = 0.005) but was not related to methemoglobin, total hemoglobin, percentage of hemoglobin S, or percentage of hemoglobin F.
authors.affiliation: Department of Pediatrics, Medical Center of Delaware, Newark 19718.
authors.forename: J A
authors.initials: JA
authors.lastname: Craft
authors.forename: E
authors.initials: E
authors.lastname: Alessandrini
authors.forename: L B
authors.initials: LB
authors.lastname: Kenney
authors.forename: B
authors.initials: B
authors.lastname: Klein
authors.forename: G
authors.initials: G
authors.lastname: Bray
authors.forename: N L
authors.initials: NL
authors.lastname: Luban
authors.forename: R
authors.initials: R
authors.lastname: Meek
authors.forename: V M
authors.initials: VM
authors.lastname: Nadkarni
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D016014:Linear Models; D010092:Oximetry; D010100:Oxygen / Q000097:blood*
chemical_list: D010100:Oxygen