Optic tract atrophy with cerebral arteriovenous malformations: direct and transsynaptic degeneration.
Three patients with postgeniculate cerebral arteriovenous malformations (AVM) had band atrophy of the contralateral optic nerve. One patient had homonymous hemioptic hypoplasia. These cases might have been construed as demonstrating transsynaptic degeneration across the lateral geniculate nucleus to the anterior visual pathway. However, neuroimaging studies revealed abnormal deep venous drainage remote from the AVM nidus that directly involved the lateral geniculate nucleus and posterior optic tract.
Kupersmith
M J
MJ
Department of Neurology, New York University Medical Center, NY.
Vargas
M
M
Hoyt
W F
WF
Berenstein
A
A
D000328:Adult; D002533:Cerebral Angiography; D002550:Cerebral Veins / Q000000981:diagnostic imaging; D005260:Female; D005829:Geniculate Bodies / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009410:Nerve Degeneration; D009887:Ophthalmoscopy; D009896:Optic Atrophy / Q000150:complications* / Q000473:pathology* / Q000503:physiopathology; D009898:Optic Disk / Q000473:pathology; D013569:Synapses / Q000648:ultrastructure*; D014794:Visual Fields