Novel 2,4-diamino-5-substituted furo[2,3-d]-pyrimidines as potential antifolates.
Gangjee
A
A
Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282.
Devraj
R
R
Queener
S F
SF
Kisliuk
R L
RL
D000818:Animals; D005493:Folic Acid Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology*; D006801:Humans; D007202:Indicators and Reagents; D007780:Lacticaseibacillus casei / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008958:Models, Molecular; D015394:Molecular Structure; D011010:Pneumocystis / Q000201:enzymology; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology*; D051381:Rats; D013329:Structure-Activity Relationship; D014122:Toxoplasma / Q000201:enzymology
D005493:Folic Acid Antagonists; D007202:Indicators and Reagents; D011743:Pyrimidines