The combination of coculture and selective assisted hatching: results from their clinical application.
OBJECTIVE
To establish pregnancies using a combination of coculture and selective assisted hatching.


METHODS
Clinical application for a selected group of patients. Not a controlled study.


METHODS
Private infertility practice.


METHODS
Women with high basal FSH levels, ovulatory disorders, and multiple failed IVF attempts.


METHODS
Pregnancy and implantation rates.


RESULTS
Of the 95 patients who had coculture and selective assisted hatching, 45 (47.0%) have an ongoing pregnancy with a 23.0% implantation rate.


CONCLUSIONS
The combination of coculture and assisted hatching produced acceptable pregnancy and implantation rates within the selected patient population.
Wiemer
K E
KE
Northwest Center for Infertility and Reproductive Endocrinology, Margate, Florida.
Hu
Y
Y
Cuervo
M
M
Genetis
P
P
Leibowitz
D
D
D000328:Adult; D000818:Animals; D001755:Blastocyst; D002417:Cattle; D002478:Cells, Cultured; D010064:Embryo Implantation; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D008846:Micromanipulation; D011247:Pregnancy; D015044:Zona Pellucida