title: Clinical use of antineutrophil cytoplasmic antibodies.
abstract: Antineutrophil cytoplasmic antibodies (ANCAs) are found in sera from patients with vasculitis and less commonly in sera from other autoimmune diseases. ANCAs provide the only specific diagnostic test for vasculitis and are also useful in monitoring disease activity. The indirect immunofluorescence test remains the best screening test for ANCAs.
authors.affiliation: Institute of Nephrology and Urology, University College, London.
authors.forename: B
authors.initials: B
authors.lastname: Leaker
authors.forename: G
authors.initials: G
authors.lastname: Cambridge
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000302:isolation & purification*; D015415:Biomarkers; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000302:isolation & purification*; D014657:Vasculitis / Q000276:immunology*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D015415:Biomarkers; D007074:Immunoglobulin G