[A comprehensive radioisotope assessment of the effectiveness of Ferrum Lek in patients with iron-deficiency anemia].
Before and after treatment iron metabolism was evaluated in 37 iron deficient women given intravenous Ferrum Lek. In addition to standard blood counts and serum iron tests, iron metabolism was investigated with Fe-59 whole body radiometry in a low-background camera. The treatment effect was assessed in 1.3 and 6 months. The red blood cells and iron content in the serum returned to normal values. The effect persisted for 6 months. The initial 3 months iron accumulated in the depot, being further distributed in the blood. Total body iron 6 months after the treatment was at the baseline levels. It is thought adequate to use Ferrum Lek in the management of women with iron deficiency anemia.
Matveeva
N P
NP
Kaplan
M A
MA
Sloventantor
V Iu
VIu
Bozadzhiev
L L
LL
D000328:Adult; D000747:Anemia, Hypochromic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007501:Iron / Q000627:therapeutic use*; D008875:Middle Aged; D009942:Organometallic Compounds / Q000627:therapeutic use*; D011134:Polysaccharides / Q000627:therapeutic use*; D011874:Radiometry
D009942:Organometallic Compounds; D011134:Polysaccharides; C009766:ferrum lek; D007501:Iron
Kompleksnaia radioizotopnaia otsenka éffektivnosti preparata Ferrum Lek u bol'nykh zhelezodefitsitnoĭ anemieĭ.