title: An electrocochleographic study of acute low-tone sensorineural hearing loss.
abstract: Twenty-four patients with acute low-tone sensorineural hearing loss (ALHL) were examined using electrocochleography. The negative summating potential (SP) amplitude and the summating potential/action potential (AP) ratio were significantly greater in the ALHL patients than in normals. The SP/AP ratio was smaller in the ALHL patients than in patients with known Meniere's disease and moderate hearing loss, although the SP amplitude was somewhat greater in the former. An abnormal increase in the SP amplitude following click stimuli was found in 54% of the ALHL patients, while the SP/AP ratio was increased abnormally in 63% of these patients. These findings suggest that the pathophysiology of ALHL may be similar to that for endolymphatic hydrops.
authors.affiliation: Department of Otolaryngology, University of Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamasoba
authors.forename: M
authors.initials: M
authors.lastname: Sugasawa
authors.forename: S
authors.initials: S
authors.lastname: Kikuchi
authors.forename: M
authors.initials: M
authors.lastname: Yagi
authors.forename: T
authors.initials: T
authors.lastname: Harada
mesh_terms: D000161:Acoustic Stimulation; D000200:Action Potentials; D000208:Acute Disease; D000328:Adult; D001300:Audiometry, Evoked Response; D003051:Cochlea / Q000503:physiopathology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000503:physiopathology; D008875:Middle Aged