title: Anastomotic disjunction in long-term patent vascular synthetic grafts in Dacron.
abstract: This study follows the recently published paper on the in vivo behaviour of patent Dacron vascular prostheses and focuses in particular on anastomotic disjunction. The question of the evolution of anastomoses was tackled by examining its three basic components: prosthetic tissue, suture thread and arterial wall. The authors' observations were based on material taken from reoperations performed between 7 and 18 years after the first graft. These data enable the authors to affirm that the prosthesis undergoes a general physical and chemical deterioration which varies in intensity according to the type of weaving. On the contrary, in the anastomotic zone this phenomenon is not intense enough to jeopardize the anchorage of the suture thread since the original weft does not show any loss of compactness. In spite of surface morphological deterioration of various intensity, the suture threads maintain satisfactory mechanical properties and structural integrity. The artery wall in the anastomotic zone shows a massive degeneration in terms of its true anatomic structure responsible for the rupture of the suture rima. On the basis of these results the authors conclude that this phenomenon represents the "Achilles' heel" of anastomotic junction.
authors.affiliation: Institute of Pathologic Anatomy, Milan University, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Tardito
authors.forename: B
authors.initials: B
authors.lastname: Biondo
authors.forename: V
authors.initials: V
authors.lastname: Caputo
authors.forename: G
authors.initials: G
authors.lastname: Freddi
authors.forename: E
authors.initials: E
authors.lastname: Grosso
authors.forename: S
authors.initials: S
authors.lastname: Mantero
authors.forename: A
authors.initials: A
authors.lastname: Motta
authors.forename: M L
authors.initials: ML
authors.lastname: Repetti
authors.forename: L
authors.initials: L
authors.lastname: Matturri
mesh_terms: D000368:Aged; D000714:Anastomosis, Surgical; D001807:Blood Vessel Prosthesis; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D012086:Reoperation; D013314:Stress, Mechanical; D013529:Surgical Wound Dehiscence / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D013537:Sutures; D013997:Time Factors; D014654:Vascular Patency
chemical_list: D011093:Polyethylene Terephthalates