Fatal flecainide intoxication.
Two fatalities resulting from suicidal ingestion of flecainide are described. The decedents, ages 33 and 15, were otherwise healthy; both took their mothers' medications. In one case, from electrocardiographic data, there was found a high-grade conduction block with idioventricular rhythm. Blood and tissue samples from autopsy were analyzed for flecainide by gas chromatography/nitrogen-phosphorous detection and gas chromatography/mass spectrometry. Blood concentrations of 93.7 and 100 mg/L flecainide were found.
Rogers
C
C
Anderson
D T
DT
Ribe
J K
JK
Sathyavagiswaran
L
L
D000293:Adolescent; D000328:Adult; D002849:Chromatography, Gas; D005260:Female; D005424:Flecainide / Q000032:analysis / Q000506:poisoning*; D006801:Humans; D008297:Male; D013405:Suicide
D005424:Flecainide