title: [Tuberculosis in children and adolescents in orphanage and boarding schools and optimization of its prevention].
abstract: Clinical examinations and follow-up were conducted in 1641 children and adolescents at risk of tuberculosis infection. Of them, 701 examinees attended children's homes and boarding schools, 940 controls went to kindergartens and secondary schools. The trial revealed that the test group children and adolescents are at much higher risk to develop tuberculosis than controls. Primary infection and the disease were recorded in them 8.5 and 1.8 times more frequently, respectively. These facts urge compulsory introduction in children's homes and boarding schools as the foci of minor bacterial dissemination of the whole complex of antituberculosis measures, tuberculin diagnosis twice a year and isoniazid chemoprophylaxis, particularly.
authors.forename: L A
authors.initials: LA
authors.lastname: Mitinskaia
authors.forename: E S
authors.initials: ES
authors.lastname: Ivanova
authors.forename: G A
authors.initials: GA
authors.lastname: Kufakova
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001500:BCG Vaccine; D002648:Child; D002674:Child, Institutionalized; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007538:Isoniazid / Q000627:therapeutic use; D012307:Risk Factors; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control
chemical_list: D001500:BCG Vaccine; D007538:Isoniazid
vernacular_title: Tuberkulëznaia infektsiia u deteĭ i podrostkov detskikh domov i shkol-internatov i optimizatsiia profilakticheskikh meropriiatiĭ sredi nikh.