Okihiro syndrome: thenar hypoplasia and Duane anomaly in three generations.
We describe a family with five members in three generations affected by Duane anomaly, three of whom also have minor radial ray abnormalities. This appears to be inherited as an autosomal dominant condition and is probably the same condition as that described by Temtamy et al. in 1975 and Okihiro et al. in 1977. One member also has congenital clubbing of the fingers and toes.
Collins
A
A
Department of Clinical Genetics, Institute of Child Health, London, UK.
Baraitser
M
M
Pembrey
M
M
D000328:Adult; D002675:Child, Preschool; D005124:Eye Abnormalities / Q000235:genetics*; D005260:Female; D006228:Hand Deformities, Congenital / Q000235:genetics; D006801:Humans; D008297:Male; D010375:Pedigree; D013577:Syndrome; D013933:Thumb / Q000002:abnormalities*