Headache, thrombolytic therapy, and chronic subdural hemorrhage--a case report.
Subdural hematomas are well known but infrequent complications of thrombolytic therapy. Although these are usually associated with head trauma, the authors describe a case of a patient who received a particularly aggressive thrombolytic regimen and presented six months later with complaints of nothing more than a headache resistant to medical therapy, without associated neurologic manifestations, which was finally diagnosed as a chronic subdural hematoma by computerized tomography. In the era of thrombolysis, physicians should maintain a heightened index of suspicion for subdural hematoma in patients complaining of headache.
Nathan
P E
PE
Division of Cardiology, Long Island College Hospital, Brooklyn, New York.
Sonenblick
D
D
Chakote
V
V
Wolf
R
R
Sacchi
T J
TJ
D000368:Aged; D005260:Female; D006261:Headache / Q000139:chemically induced*; D006408:Hematoma, Subdural / Q000139:chemically induced*; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy; D011994:Recombinant Proteins / Q000009:adverse effects; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D010959:Tissue Plasminogen Activator / Q000009:adverse effects
D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator