title: Sequence of the alg8 and alg44 genes involved in the synthesis of alginate by Pseudomonas aeruginosa.
abstract: The alg8 and alg44 genes, which are required for alginate biosynthesis by Pseudomonas aeruginosa, are located in the alginate biosynthetic gene cluster between the algD and algE genes. The nucleotide sequence of these two genes is presented. Although the functions of the Alg8 and Alg44 proteins are not known, we believe that they may be involved in the polymerization of mannuronic acid residues to form alginate.
authors.affiliation: Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago 60612.
authors.forename: R
authors.initials: R
authors.lastname: Maharaj
authors.forename: T B
authors.initials: TB
authors.lastname: May
authors.forename: S K
authors.initials: SK
authors.lastname: Wang
authors.forename: A M
authors.initials: AM
authors.lastname: Chakrabarty
mesh_terms: D000464:Alginates / Q000378:metabolism*; D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D001483:Base Sequence; D003001:Cloning, Molecular; D004269:DNA, Bacterial; D005798:Genes, Bacterial; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D011550:Pseudomonas aeruginosa / Q000235:genetics* / Q000378:metabolism
chemical_list: C085500:Alg44 protein, Pseudomonas aeruginosa; C085499:Alg8 protein, Pseudomonas aeruginosa; D000464:Alginates; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D006603:Hexuronic Acids; D008565:Membrane Proteins; D020723:Glucuronic Acid