title: Validation of an MRI/PET landmark registration method using 3D simulated PET images and point simulations.
abstract: Three-dimensional (3D) simulated PET images generated from MRI were used to validate a multimodality registration technique based on the identification of internal anatomical landmarks. In addition, point-based simulations were compared with registration datasets acquired over 3 yr of routine use of the technique. Registration errors were found to range from 1.0 mm at the brain centre to 2.8 mm in each dimension at the brain surface.
authors.affiliation: McConnell Brain Imaging Centre, Montréal Neurological Institute, Canada.
authors.forename: P
authors.initials: P
authors.lastname: Neelin
authors.forename: J
authors.initials: J
authors.lastname: Crossman
authors.forename: D J
authors.initials: DJ
authors.lastname: Hawkes
authors.forename: Y
authors.initials: Y
authors.lastname: Ma
authors.forename: A C
authors.initials: AC
authors.lastname: Evans
mesh_terms: D003198:Computer Simulation; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015203:Reproducibility of Results; D014055:Tomography, Emission-Computed / Q000379:methods*