A comparison of narrow band phototherapy (TL-01) and photochemotherapy (PUVA) in the management of polymorphic light eruption.
Twenty-five patients suffering from severe polymorphic light eruption (PLE) were randomized to either photochemotherapy (PUVA) or narrow-band phototherapy (TL-01 UVB) treatment in early spring; patients receiving UVB were given placebo tablets to achieve a matching therapy procedure. During the 4 months following treatment, patient exposure to solar UVB was monitored with polysulphone badges. PLE occurrence, severity, and restriction of outdoor activity were recorded, using weekly diary-sheets. Analysis of covariance on this data, using the logarithm of UVB exposure as the explanatory variable, showed no significant differences between the treatments. TL-01 UVB is an effective alternative to PUVA in the management of PLE.
Bilsland
D
D
Department of Photobiology, Ninewells Hospital and Medical School, Dundee, U.K.
George
S A
SA
Gibbs
N K
NK
Aitchison
T
T
Johnson
B E
BE
Ferguson
J
J
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D010787:Photosensitivity Disorders / Q000517:prevention & control*; D012621:Seasons; D014467:Ultraviolet Therapy / Q000295:instrumentation