title: Ivermectin levels in human breastmilk.
abstract: Ivermectin levels were measured in breastmilk and plasma of 4 healthy mothers after an oral 150 micrograms/kg dose. Mean +/- S.D. plasma and milk values were 37.9 +/- 0.54 and 14.13 +/- 0.43 (ng/ml) respectively. Steady-state ivermectin levels in milk were low. Our results suggest that exclusion of lactating mothers from mass chemotherapy with ivermectin may be unnecessary.
authors.affiliation: Department of Pharmacology and Therapeutics, University of Nigeria Teaching Hospital, Enugu.
authors.forename: J E
authors.initials: JE
authors.lastname: Ogbuokiri
authors.forename: B C
authors.initials: BC
authors.lastname: Ozumba
authors.forename: P O
authors.initials: PO
authors.lastname: Okonkwo
mesh_terms: D000328:Adult; D001942:Breast Feeding; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000032:analysis* / Q000097:blood; D007774:Lactation; D008895:Milk, Human / Q000737:chemistry*; D009549:Nigeria; D012424:Rural Population
chemical_list: D007559:Ivermectin