title: Ovulation induction with GnRH agonist and human menopausal gonadotropins: response in patients with one versus two ovaries.
abstract: OBJECTIVE
  To examine the effect of oophorectomy on response to gonadotropin releasing hormone-agonist/human menopausal gonadotropin (GnRH-a/hMG) for in vitro fertilization (IVF).
  
  
  METHODS
  Retrospective review.
  
  
  METHODS
  Tertiary care academic institution.
  
  
  METHODS
  Ninety-one infertile patients undergoing IVF. Eighty-four women had two ovaries and seven had only one ovary.
  
  
  RESULTS
  There was no difference observed between women with one versus two ovaries with regard to response to medications, hormone production, number of oocytes retrieved and fertilized, or the number of embryos cleaved and transferred.
  
  
  CONCLUSIONS
  Women with only one ovary are at no reproductive disadvantage when undergoing ovulation induction for IVF.
authors.affiliation: Yale University School of Medicine, Department of Obstetrics & Gynecology, New Haven, Connecticut.
authors.forename: A S
authors.initials: AS
authors.lastname: Penzias
authors.forename: J N
authors.initials: JN
authors.lastname: Gutmann
authors.forename: F N
authors.initials: FN
authors.lastname: Shamma
authors.forename: A I
authors.initials: AI
authors.lastname: LaMorte
authors.forename: A H
authors.initials: AH
authors.lastname: DeCherney
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D016729:Leuprolide / Q000627:therapeutic use*; D017274:Nafarelin / Q000627:therapeutic use*; D010052:Ovariectomy / Q000009:adverse effects; D010053:Ovary / Q000502:physiology*; D010062:Ovulation Induction / Q000379:methods*; D011374:Progesterone / Q000097:blood; D012044:Regression Analysis; D012189:Retrospective Studies
chemical_list: D006063:Chorionic Gonadotropin; D017274:Nafarelin; D011374:Progesterone; D004958:Estradiol; D016729:Leuprolide