title: [Intrathymic regulation of proliferation of medullary thymocytes in CBA mice].
abstract: The action of non-peptide mitogenic factor (NMF) on the following thymocytes populations: common cortisone-resistant (CR); cortisone-resistant cells without macrophages (CR-M) and mature (PNP-) thymocytes was studied. It has been shown, that NMF shifts the catabolism of (8-(14) C) AMP towards hypoxanthine accumulation as well as stimulates the (2(-14) C) Thd incorporation in DNA of thymocyte populations to an increasing degree when comparing CR with PNA- cells. The action of NMF is not mediated by macrophages. It has been concluded that mature PNP- population is the target for NMF.
authors.forename: I A
authors.initials: IA
authors.lastname: Bezvershenko
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Selishcheva
authors.forename: V Kh
authors.initials: VKh
authors.lastname: Premislov
authors.forename: M G
authors.initials: MG
authors.lastname: Boĭko
mesh_terms: D000249:Adenosine Monophosphate / Q000378:metabolism; D000818:Animals; D001685:Biological Factors / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D003348:Cortisone / Q000494:pharmacology; D004247:DNA / Q000378:metabolism; D004351:Drug Resistance; D019271:Hypoxanthine; D007042:Hypoxanthines / Q000378:metabolism; D008264:Macrophages / Q000502:physiology; D051379:Mice; D008808:Mice, Inbred CBA; D008934:Mitogens / Q000502:physiology*; D013936:Thymidine / Q000378:metabolism; D013950:Thymus Gland / Q000166:cytology*
chemical_list: D001685:Biological Factors; D007042:Hypoxanthines; D008934:Mitogens; D019271:Hypoxanthine; D000249:Adenosine Monophosphate; D004247:DNA; D003348:Cortisone; D013936:Thymidine
vernacular_title: Vnutrishn'otymichna rehuliatsiia proliferatsiï meduliarovykh tymotsytiv mysheĭ liniï CBA.