title: The chromosomal distribution of Mus musculus-like AT-rich heterochromatin in the M. dunni complex as revealed by AluI digestion of metaphase chromosomes.
abstract: In situ digestion of metaphase chromosomes with AluI revealed differences in the distribution of Mus musculus-like AT-rich heterochromatin in the complements of the Indian pygmy field mice, M. booduga and M. dunni. In M. booduga, although the banding pattern was almost comparable to that of M. musculus, AluI-resistant bands were much reduced in size at the centromeric regions. In all three chromosome types of the M. dunni complex, M. musculus-like AT-rich heterochromatin was found to be confined mainly to two small segments on the short arm of the X chromosome. This AT-rich heterochromatin varied greatly in both position and quantity in the two X chromosomes. In addition to the polymorphism, a whole block of M. musculus-like AT-rich heterochromatin was found at the centromeric region of an autosome in one individual of M. dunni.
authors.affiliation: Cytogenetics Laboratory, Banaras Hindu University, Varanasi, India.
authors.forename: A S
authors.initials: AS
authors.lastname: Balajee
authors.forename: T
authors.initials: T
authors.lastname: Sharma
mesh_terms: D000225:Adenine; D000818:Animals; D001482:Base Composition; D002874:Chromosome Mapping; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism*; D005260:Female; D006570:Heterochromatin / Q000737:chemistry*; D008677:Metaphase; D051379:Mice; D013941:Thymine
chemical_list: D006570:Heterochromatin; C024669:endodeoxyribonuclease AluI; D015252:Deoxyribonucleases, Type II Site-Specific; D000225:Adenine; D013941:Thymine