Neural-immunologic interactions in asthma.
Recent investigations offer insights into the possible cause of asthma: Rather than being due to either neural or immunologic events, the fault may lie in concurrent malfunctioning of two interacting systems. Antigenic stimulation, for example, can affect neural depolarization and firing; by the same token, nerve stimulation can affect the growth and function of inflammatory cells.
Undem
B J
BJ
Johns Hopkins University Asthma and Allergy Center, Baltimore.
D000818:Animals; D016525:Antigenic Modulation; D001249:Asthma / Q000276:immunology / Q000503:physiopathology*; D001986:Bronchial Spasm / Q000503:physiopathology; D006168:Guinea Pigs; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D015213:Neuroimmunomodulation; D051381:Rats; D012137:Respiratory System / Q000294:innervation; D011984:Sensory Receptor Cells; D015320:Tachykinins / Q000096:biosynthesis
D015320:Tachykinins