title: Implication of prescriptions for nitrates: 7 year follow up of patients treated for angina in general practice.
abstract: OBJECTIVE
  To determine the demand placed on local cardiological services by patients prescribed nitrates for ischaemic heart disease.
  
  
  METHODS
  A follow up study of a cohort of patients identified in 1985.
  
  
  METHODS
  Nottingham Health District.
  
  
  METHODS
  Four hundred and ninety nine patients prescribed nitrates in 1985 for presumed ischaemic heart disease.
  
  
  METHODS
  Referral to medical outpatients, admittance to hospital with chest pain, cardiological investigations, and mortality.
  
  
  RESULTS
  Over the seven year period 26% of patients were admitted urgently with chest pain and 15% were referred to the medical outpatient department--a referral rate of 6% a year. 4% of patients had an exercise test and 6% a coronary angiogram. The death rate was 6% a year and a higher proportion died of cardiovascular causes than would be expected in the general population.
  
  
  CONCLUSIONS
  Prescription of nitrate is useful in the determination of the prevalence of ischaemic heart disease. Most patients with angina are still treated within the community, and the rate of specialist investigation remains low.
authors.affiliation: University Hospital, Nottingham.
authors.forename: K W
authors.initials: KW
authors.lastname: Clarke
authors.forename: D
authors.initials: D
authors.lastname: Gray
authors.forename: J R
authors.initials: JR
authors.lastname: Hampton
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000188:drug therapy* / Q000401:mortality; D016507:Cardiology Service, Hospital / Q000706:statistics & numerical data; D002423:Cause of Death; D004739:England / Q000453:epidemiology; D005194:Family Practice; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000453:epidemiology / Q000401:mortality; D009566:Nitrates / Q000627:therapeutic use*; D015995:Prevalence
chemical_list: D009566:Nitrates