[The blood microcirculatory bed of the liver in fetuses under increased physical loading in pregnant rats].
Morphological and morphometrical methods were used to study the hemomicrocirculatory bed of fetuses during greater physical exercise of pregnant rats during 18 and 21 days. As a result, a mosaic picture is noted in the liver. There appear areas with sharply constricted vessels which alternate with dilated vessels and loci of hemorrhages of different sizes. In the areas of the liver with narrow vessels minimum dystrophic changes were noted. In areas with dilated vessels, particularly in the II and III zones of the acinus, there were pronounced dystrophic alterations of the walls of vessels and hepatocytes which is a manifestation of the organ hypoxia. Besides the dystrophic processes in the liver there appear symptoms of adaptation-compensation phenomena such as a greater amount of foci of hemopoiesis, elevated activity of redox enzymes, higher content of glycogen in hepatocytes by the 21st day. The increased physical exercise of the mother results in faster differentiation of the walls of the hemomicrocirculatory bed vessels (interlobular veins and arterioles, sinusoids, central and collecting veins) of the fetus liver, mainly in the portal vein system, and accelerated processes of the formation of its architectonics.
Rashidov
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D000818:Animals; D005260:Female; D005865:Gestational Age; D006651:Histocytochemistry; D008099:Liver / Q000098:blood supply* / Q000196:embryology / Q000201:enzymology; D008833:Microcirculation / Q000196:embryology / Q000201:enzymology; D005082:Physical Exertion / Q000502:physiology*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D051381:Rats; D013550:Swimming
Gemomikrotsirkuliatornoe ruslo pecheni plodov pri povyshennoĭ fizicheskoĭ nagruzke beremennykh krys.