title: Assignment of the phosducin (PDC) gene to human chromosome 1q25-1q32.1 by somatic cell hybridization and in situ hybridization.
abstract: Phosducin is a soluble photoreceptor phosphoprotein that probably modulates phototransduction in the retina and thus qualifies as a potential candidate gene for retinitis pigmentosa. Using both human/mouse somatic cell hybrids and in situ hybridization to human metaphase chromosomes, we have mapped this gene to chromosome 1q25-1q32.1.
authors.affiliation: Department of Medicine, Jules Stein Eye Institute, UCLA Center for the Health Sciences 90024.
authors.forename: R S
authors.initials: RS
authors.lastname: Sparkes
authors.forename: R H
authors.initials: RH
authors.lastname: Lee
authors.forename: T
authors.initials: T
authors.lastname: Shinohara
authors.forename: C M
authors.initials: CM
authors.lastname: Craft
authors.forename: T
authors.initials: T
authors.lastname: Kojis
authors.forename: I
authors.initials: I
authors.lastname: Klisak
authors.forename: C
authors.initials: C
authors.lastname: Heinzmann
authors.forename: J B
authors.initials: JB
authors.lastname: Bateman
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D005136:Eye Proteins / Q000235:genetics*; D020555:GTP-Binding Protein Regulators; D006801:Humans; D006822:Hybrid Cells; D017403:In Situ Hybridization; D051379:Mice; D010750:Phosphoproteins / Q000235:genetics*
chemical_list: D005136:Eye Proteins; D020555:GTP-Binding Protein Regulators; D010750:Phosphoproteins; C065631:phosducin