title: [Clinical iconographic dissociation in a case of monophasic demyelinating disease].
abstract: We report a patient with monophasic inflammatory demyelinizing disease whose initial symptoms and imaging studies led to the undertaking of a cerebral biopsy for suspicion of an expansive process. The evolution of the both the CT and MR imaging studies with contrast and overall the surprising size of the lesions in MR when the patient was clinically asymptomatic support the hypothesis of residual dysfunction in the hemato-encephalic barrier as a cause of the persistence of MR images. This explanation appears more acceptable than its attribution to a gliosis secondary to previous inflammation.
authors.affiliation: Servicio de Neurología, Hospital General de Especialidades Virgen de las Nieves, Granada.
authors.forename: T
authors.initials: T
authors.lastname: García Gómez
authors.forename: J F
authors.initials: JF
authors.lastname: Maestre Moreno
authors.forename: J A
authors.initials: JA
authors.lastname: Tamayo Toledo
authors.forename: A
authors.initials: A
authors.lastname: Mínguez Castellanos
authors.forename: J
authors.initials: J
authors.lastname: Foronda Bengoa
authors.forename: P
authors.initials: P
authors.lastname: Serrano Castro
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001812:Blood-Brain Barrier; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000503:physiopathology; D004679:Encephalomyelitis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Disociación clinicoiconográfica en un caso de enfermedad desmielinizante monofásica.