title: Antibiotic susceptibility and phage typing of methicillin-resistant Staphylococcus aureus clinical isolates from blood cultures of 692 patients in 15 Israeli hospitals.
abstract: Six hundred ninety-two clinical isolates of Staphylococcus aureus were collected from blood cultures of 692 patients in 15 Israeli hospitals over a two year period. Antibiotic sensitivity was tested by the standard disk diffusion technique. Of these isolates, 41.6% were methicillin-resistant (MRSA). All 288 MRSA isolates were sensitive to vancomycin and pristinomycin; 98.6% were sensitive to fucidine; 97.9% to imipenem; 79% to rifampicin; 63.6% to amikacin; 54.5% to augmentin; 36.4% to clindamycin; 12.6% to ciprofloxacin; 11.9% to cotrimoxazole and ofloxacin; 10.5% to gentamicin; 9.8% to erythromycin; and 8.4% to norfloxacin. Phage typing was determined by using the international set of phages. All the isolates that were sensitive to Group I phages, and 91.8% of those sensitive to Group II phages, were sensitive to methicillin. Of the isolates that were sensitive to Group III phages, 79.2% were methicillin-resistant and 72.4% of the latter were sensitive to phages 75/85. Of the isolates that were sensitive to Group III and miscellaneous phages, 50.7% were methicillin-resistant and 71% of the latter were sensitive to phages 75/85 as well.
authors.affiliation: Department of Microbiology, Beilinson Medical Center, Petach Tiqva, Israel.
authors.forename: Z
authors.initials: Z
authors.lastname: Samra
authors.forename: R
authors.initials: R
authors.lastname: Gadba
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016470:Bacteremia / Q000382:microbiology*; D001434:Bacteriophage Typing; D006761:Hospitals; D006801:Humans; D007557:Israel; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents