title: The gene encoding myeloid alpha-3-fucosyl-transferase (FUT4) is located between D1 1S388 and D11S919 on 11q21.
abstract: The last step in the biosynthesis of Le(x) antigen, the addition of a fucose to precursor polysaccharides, can be catalyzed by different alpha-3-fucosyltransferases. We localized the gene (FUT4) encoding myeloid alpha-3-fucosyltransferase by PCR assay using panels of somatic cell and radiation hybrids which retain different rearrangements of chromosome 11. FUT4 was assigned to chromosome band 11q21 between D11S388 and D11S919.
authors.affiliation: INSERM U178, Villejuif, France.
authors.forename: I
authors.initials: I
authors.lastname: Reguigne
authors.forename: M R
authors.initials: MR
authors.lastname: James
authors.forename: C W
authors.initials: CW
authors.lastname: Richard
authors.forename: R
authors.initials: R
authors.lastname: Mollicone
authors.forename: A
authors.initials: A
authors.lastname: Seawright
authors.forename: J B
authors.initials: JB
authors.lastname: Lowe
authors.forename: R
authors.initials: R
authors.lastname: Oriol
authors.forename: P
authors.initials: P
authors.lastname: Couillin
mesh_terms: D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D006224:Cricetinae; D004247:DNA; D015342:DNA Probes; D005647:Fucosyltransferases / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data
chemical_list: D015342:DNA Probes; D004247:DNA; D005647:Fucosyltransferases; C031692:galactoside 3-fucosyltransferase