title: Immunohistological study on bovine small intestine including gut associated lymphoid tissue using monoclonal antibodies to WC1, TCR1 and BoCD3.
abstract: Selected antibodies (mAbs) that clustered in temporary cluster TC22 (WC1) and TC36 (TCR1) and one unclustered mAb thought to detect BoCD3 were used to compare the distribution of T and B cells and subpopulations of WC1+ or TCR1+ cells in fetal, calf, and young adult gut associated lymphoid tissue. Cells putatively positive for BoCD3 (MM1A) were detected in the interfollicular tissue similar to the pattern noted for BoCD2+ or BoCD5+ cells. WC1+ or TCR1+ cells were detected in small numbers in follicles and interfollicular tissue. Numerous WC1+ or TCR1+ cells were evident in the lamina propria and epithelia, with the highest frequency evident in tissues from animals 8 months of age.
authors.affiliation: Department of Veterinary Pathology, Faculty of Agriculture, Iwate University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Okada
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Murakami
authors.forename: W C
authors.initials: WC
authors.lastname: Davis
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D015703:Antigens, CD / Q000276:immunology; D002417:Cattle / Q000276:immunology*; D007124:Immunoenzyme Techniques / Q000662:veterinary; D007413:Intestinal Mucosa / Q000166:cytology; D007421:Intestine, Small / Q000166:cytology* / Q000276:immunology; D016131:Lymphocyte Subsets / Q000166:cytology* / Q000276:immunology; D010581:Peyer's Patches / Q000166:cytology*; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D016692:Receptors, Antigen, T-Cell, gamma-delta