Enzyme-activated antagonists of the strychnine-insensitive glycine/NMDA receptor.
Salituro
F G
FG
Marion Merrell Dow Research Institute, Cincinnati, Ohio 45215.
Tomlinson
R C
RC
Baron
B M
BM
Palfreyman
M G
MG
McDonald
I A
IA
Schmidt
W
W
Wu
H Q
HQ
Guidetti
P
P
Schwarcz
R
R
D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D002540:Cerebral Cortex / Q000201:enzymology; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D005998:Glycine / Q000037:antagonists & inhibitors* / Q000378:metabolism; D007700:Kinetics; D007737:Kynurenine / Q000031:analogs & derivatives* / Q000378:metabolism*; D008190:Lyases; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013331:Strychnine / Q000494:pharmacology*; D000637:Transaminases / Q000378:metabolism*
D016194:Receptors, N-Methyl-D-Aspartate; D007737:Kynurenine; C027883:4-chlorokynurenine; D000637:Transaminases; C427605:glutamine - phenylpyruvate transaminase; C021481:kynurenine-oxoglutarate transaminase; D008190:Lyases; D013331:Strychnine; D005998:Glycine