Heterotopic gastric mucosa and Helicobacter pylori infection in Meckel's diverticulum in Indian subjects.
Two of twenty nine (6.8%) patients who had undergone resection of Meckel's diverticulum demonstrated heterotopic gastric mucosa. In both these patients gastric mucosa was of antral type. Remaining 27 of 29 (93.2%) patients with Meckel's diverticulum had intestinal mucosa. 9 of 29 (31%) patients with Meckel's resected were symptomatic (8 bleeding, 1 perforation) and all 9 were negative for heterotopic gastric mucosa. Helicobacter pylori (H. pylori) was absent in both patients with intestinal mucosa. Antral biopsy from 13 partial gastrectomy specimens (surgery done for carcinoma stomach) were used as methodological controls and 7 of 13 (54%) showed H. pylori colonization. We conclude that (i) incidence of gastric mucosa is 6.8% in Meckel's diverticulum in our population, (ii) presence of heterotopic gastric mucosa is unlikely to be associated with complications of Meckel's diverticulum and (iii) heterotopic mucosa in Meckel's diverticulum is not commonly colonized by H. pylori.
Parikh
S S
SS
Department of Gastroenterology and Pathology, BYL Nair Ch Hospital and TN Medical College, Bombay.
Ranganathan
S
S
Prabhu
S R
SR
Kalro
R H
RH
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000150:complications*; D005260:Female; D005753:Gastric Mucosa; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori; D006801:Humans; D007077:Ileal Diseases / Q000150:complications; D008297:Male; D008467:Meckel Diverticulum / Q000150:complications*; D008875:Middle Aged