[Role of DNA double strand breaks in the radiation structural mutagenesis in eukaryotic cells].
The latest experimental findings in the field of radiation-induced structural mutagenesis especially concerned with the role of the DNA double strand breaks (DSBs) in the formation of chromosome aberrations were analyzed. It was shown slow-repairable and non-repairable DSBs appeared to be the DNA critical damages leading to aberrations.
Obaturov
G M
GM
Filimonov
A S
AS
D000818:Animals; D002869:Chromosome Aberrations; D004247:DNA / Q000096:biosynthesis / Q000528:radiation effects*; D004249:DNA Damage / Q000528:radiation effects*; D004260:DNA Repair / Q000528:radiation effects*; D005057:Eukaryotic Cells / Q000378:metabolism / Q000528:radiation effects*; D016296:Mutagenesis / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000235:genetics*
D004247:DNA
Rol dvunitevykh razryvov DNK v protsessakh radiatsionnogo strukturnogo mutageneza v éukarioticheskikh kletkakh.