title: Total reaction time: a new approach in early HIV encephalopathy?
abstract: In an attempt to develop better methods for diagnosis, screening and serial assessment of HIV-1-associated cognitive/motor complex, we have added a motor component to tests of reaction time, defining the new parameter as total reaction time. Thirty-four non-drug-using, HIV-positive men underwent four different tests of total reaction time. All four tests reached a level of statistical significance, both for a group of patients with early disease and for a group of patients with symptoms, compared with a control group. Total reaction time had a better discriminatory ability than standard reaction time, particularly for patients with early disease. It is suggested that neuropsychological studies of HIV-1-associated cognitive/motor complex should include tests of total reaction time.
authors.affiliation: Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway.
authors.forename: O
authors.initials: O
authors.lastname: Dunlop
authors.forename: R
authors.initials: R
authors.lastname: Bjørklund
authors.forename: M
authors.initials: M
authors.lastname: Abdelnoor
authors.forename: B
authors.initials: B
authors.lastname: Myrvang
mesh_terms: D015526:AIDS Dementia Complex / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology; D000328:Adult; D001307:Auditory Perception / Q000502:physiology; D002755:Choice Behavior / Q000502:physiology; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009460:Neurologic Examination; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*; D012016:Reference Values; D014796:Visual Perception / Q000502:physiology