Outcome of 21 patients with biliary atresia living more than 10 years.
The outcome of 21 survivors (8 males, 13 females; age range, 11 to 29 years) followed for > 10 years after surgery for biliary atresia are discussed. Of the 21 patients, 18 with type III disease had hepatic portoenterostomy (Kasai operation), and 3 with type I disease had hepaticoenterostomy. Twenty patients are alive leading almost normal lives; however, 13 (61.9%) patients did have a history of complications, including hemorrhage from esophageal varices in 10, from a gastric ulcer or erosion in 3, and from a duodenal ulcer in 2; biliary reobstruction in 3; and multiple pulmonary arteriovenous fistulae in 2. Of those with complications, 7 required surgery. One died suddenly at the age of 19 years of a bleeding gastric ulcer. Liver function is normal in 9 (45.0%) of the 20 alive patients, 2 (10.0%) have slight hepatic dysfunction, and 9 (45.0%) have mild-to-moderate hepatic dysfunction. Liver function is almost normal in 3 patients who had a history of variceal hemorrhage.
Toyosaka
A
A
First Department of Surgery, Hyogo College of Medicine, Japan.
Okamoto
E
E
Okasora
T
T
Nose
K
K
Tomimoto
Y
Y
D000293:Adolescent; D000328:Adult; D001656:Biliary Atresia / Q000145:classification / Q000601:surgery*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D011171:Portoenterostomy, Hepatic; D011183:Postoperative Complications / Q000097:blood / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality / Q000601:surgery; D011379:Prognosis; D012086:Reoperation; D017741:Survivors; D013997:Time Factors; D016896:Treatment Outcome