Total reaction time: a new approach in early HIV encephalopathy?
In an attempt to develop better methods for diagnosis, screening and serial assessment of HIV-1-associated cognitive/motor complex, we have added a motor component to tests of reaction time, defining the new parameter as total reaction time. Thirty-four non-drug-using, HIV-positive men underwent four different tests of total reaction time. All four tests reached a level of statistical significance, both for a group of patients with early disease and for a group of patients with symptoms, compared with a control group. Total reaction time had a better discriminatory ability than standard reaction time, particularly for patients with early disease. It is suggested that neuropsychological studies of HIV-1-associated cognitive/motor complex should include tests of total reaction time.
Dunlop
O
O
Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway.
Bjørklund
R
R
Abdelnoor
M
M
Myrvang
B
B
D015526:AIDS Dementia Complex / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology; D000328:Adult; D001307:Auditory Perception / Q000502:physiology; D002755:Choice Behavior / Q000502:physiology; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009460:Neurologic Examination; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*; D012016:Reference Values; D014796:Visual Perception / Q000502:physiology