Frequent amplification of a short chain dehydrogenase gene in methotrexate resistant Leishmania.
Papadopoulou
B
B
Département de Microbiologie, Université Laval, Québec, Canada.
Ouellette
M
M
D000818:Animals; D004351:Drug Resistance / Q000235:genetics; D005784:Gene Amplification; D017125:Genes, Protozoan; D007891:Leishmania / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D008727:Methotrexate / Q000378:metabolism / Q000633:toxicity*; D010088:Oxidoreductases / Q000235:genetics*; D014162:Transfection
D010088:Oxidoreductases; C085592:pteridine reductase; D008727:Methotrexate