title: Twelve cases of glottic carcinoma in situ treated by radiotherapy: an observation on clinical course versus response.
abstract: Carcinoma in situ (CIS) of the glottis is an uncommon and poorly understood condition with few, large, long-term studies. Twelve cases are presented which were treated with radiotherapy. At three-year follow-up all the patients are disease free and in 83 per cent the mucosa has returned to normal. The alternative methods of treatment are discussed.
authors.affiliation: Department of Otolaryngology, East Birmingham Hospital.
authors.forename: J P
authors.initials: JP
authors.lastname: Brooks
authors.forename: D W
authors.initials: DW
authors.lastname: Morgan
authors.forename: J
authors.initials: J
authors.lastname: Glaholm
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D005931:Glottis / Q000528:radiation effects; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000209:etiology; D011882:Radiotherapy, High-Energy / Q000009:adverse effects; D012907:Smoking