title: Quantitative analysis of bone metastasis in prostate cancer.
abstract: A new method of quantitative analysis of bone metastasis in prostate cancer is described. By using a variance-dependent filter and a smoothing filter, the increased uptake lesions were distinctly demonstrated on the bone scintigraphy. The images were divided into several areas and analyzed. These procedures resulted in a clear identification of the metastatic lesions. Repeated measurements of the metastatic areas from the same scintigrams disclosed a high reproducibility. This method appears to be highly consistent and clinically applicable.
authors.affiliation: Department of Urology, Yamagata University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kubota
authors.forename: T
authors.initials: T
authors.lastname: Nakada
authors.forename: I
authors.initials: I
authors.lastname: Sasagawa
authors.forename: K
authors.initials: K
authors.lastname: Izumiya
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D011877:Radionuclide Imaging; D015203:Reproducibility of Results