title: Rinderpest vaccination responses among calves and adult cattle in Uganda monitored using ELISA assay.
abstract: Responses to the Plowright Rinderpest vaccine by 43 calves and 70 adult cattle in Uganda in 1990, through the production of IgG antibodies, were monitored for 4 weeks using the ELISA assay. 80% of the calves were seronegative before vaccination of which 32% remained seronegative and 68% subsequently seroconverted at 2 weeks postvaccination. 20% of the calves were seropositive before vaccination but registered a decline during the 2nd and 4th weeks postvaccination. 50% of adult Ankole cattle seroconverted after 3 weeks postvaccination, while the other 50% of them, which were seropositive before vaccination, showed a decline in seronegative levels during the first 2 weeks postvaccination, but increased again at the 4th week. 90% of Friesian adult cattle were seronegative before vaccination; however, they all seroconverted within the 2nd week of postvaccination. The other 10% remained seropositive, with a slight decline of antibody levels during the 4 weeks after vaccination.
authors.affiliation: Faculty of Veterinary Medicine, Department of Veterinary Public Health and Preventive Medicine, Makerere University, Kampala.
authors.forename: J
authors.initials: J
authors.lastname: Opuda-Asibo
authors.forename: L
authors.initials: L
authors.lastname: Siefert
authors.forename: L
authors.initials: L
authors.lastname: Omamure-Epaye
authors.forename: T
authors.initials: T
authors.lastname: Ekopai
authors.forename: H
authors.initials: H
authors.lastname: Kyeyamwa
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000096:biosynthesis*; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D004797:Enzyme-Linked Immunosorbent Assay; D007074:Immunoglobulin G / Q000096:biosynthesis; D007279:Injections, Subcutaneous / Q000662:veterinary; D012301:Rinderpest / Q000517:prevention & control*; D012302:Rinderpest virus / Q000276:immunology*; D013997:Time Factors; D014454:Uganda; D014611:Vaccination / Q000662:veterinary; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D014765:Viral Vaccines