The glycolic acid trichloroacetic acid peel.
BACKGROUND
Chemical peeling has become increasingly popular. Technique is more critical in medium depth peeling than with deeper peels because of variable penetration of the trichloroacetic acid.


OBJECTIVE
This article describes a novel use of two caustic agents, glycolic acid and trichloroacetic acid, to effect a predictable approach to medium depth peeling.


METHODS
Without other skin preparation, 70% glycolic acid was applied to the entire face and diluted with water after 2 minutes. Then, 35% trichloroacetic acid was applied over the same areas. Biopsies were done on selected patients after 24 hours and 30, 60, and 90 days.


RESULTS
Both clinically and histologically the glycolic trichloroacetic acid peel resulted in medium depth injury. Improvement in pigmentary dyschromias and actinic damage was impressive.


CONCLUSIONS
The GA-TCA peel provides a consistent approach to medium depth peeling to add to the armamentarium of the dermatologic surgeon.
Coleman
W P
WP
Department of Dermatology, Tulane University School of Medicine, New Orleans, Louisiana.
Futrell
J M
JM
D000328:Adult; D001706:Biopsy; D002615:Chemexfoliation / Q000379:methods*; D005145:Face; D005260:Female; D006016:Glycolates / Q000008:administration & dosage*; D006801:Humans; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D014238:Trichloroacetic Acid / Q000008:administration & dosage*
D006016:Glycolates; C031149:glycolic acid; D014238:Trichloroacetic Acid