title: Folate metabolites as modulators of antitumor drug activity.
authors.affiliation: Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston 29425-2211.
authors.forename: D G
authors.initials: DG
authors.lastname: Priest
authors.forename: J C
authors.initials: JC
authors.lastname: Schmitz
authors.forename: M A
authors.initials: MA
authors.lastname: Bunni
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001692:Biological Transport; D001711:Biotransformation; D002460:Cell Line; D015179:Colorectal Neoplasms / Q000188:drug therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D005492:Folic Acid / Q000097:blood / Q000378:metabolism*; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage / Q000378:metabolism* / Q000627:therapeutic use; D010051:Ovarian Neoplasms; D013763:Tetrahydrofolates / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D014407:Tumor Cells, Cultured
chemical_list: D013763:Tetrahydrofolates; C013123:5,10-methylenetetrahydrofolic acid; D005492:Folic Acid; D002955:Leucovorin; D005472:Fluorouracil