title: Three-dimensional surface display using 123I-IMP in a case of motor neuron disease with dementia.
abstract: A case of motor neuron disease with dementia is presented. A brain CT showed atrophic changes mainly in the left frontal cortex, and 123I-IMP SPECT disclosed a decrease in 123I-IMP uptake in the frontal regions. To distinguish a subregion related to dementia from that related to motor system disorders, a three-dimensional surface display with 123I-IMP was reconstructed. The imaging method clearly demonstrated cortical hypoperfusion in the inferomedial frontal cortex and the motor-sensory cortex. These findings suggest that dementia may be due to the former lesion and motor system disorders due to the latter lesion, respectively.
authors.affiliation: Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
authors.forename: B
authors.initials: B
authors.lastname: Okuda
authors.forename: K
authors.initials: K
authors.lastname: Kawabata
authors.forename: H
authors.initials: H
authors.lastname: Tachibana
authors.forename: M
authors.initials: M
authors.lastname: Sugita
authors.forename: M
authors.initials: M
authors.lastname: Fukuchi
mesh_terms: D000662:Amphetamines; D000690:Amyotrophic Lateral Sclerosis / Q000000981:diagnostic imaging*; D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging; D003704:Dementia / Q000000981:diagnostic imaging*; D005625:Frontal Lobe / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000000981:diagnostic imaging*; D012039:Regional Blood Flow / Q000502:physiology; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine