Task force report on the outcome of pregnancies and children conceived by in vitro fertilization (France: 1987 to 1989).
OBJECTIVE
To describe the outcome of pregnancies conceived by IVF and the follow-up of the children after a minimum of 1 year of life.


METHODS
Survey of clinical pregnancies and follow-up of the children and comparison with national statistics.


METHODS
All clinical pregnancies from 11 French centers between January 1987 and June 1989.


METHODS
A total of 1,637 pregnancies resulting in 1,263 deliveries and 1,669 live-born or still-born children and 1,411 alive children after 1 year.


METHODS
Gestational age of birth, birth weight, mortality rates, prevalence of congenital malformation, and prevalence of disorders during the follow-up of the children.


RESULTS
The preterm birth rate was 22.7% of all deliveries and 12.2% of single deliveries compared with 5.6% in France, and 34.7% of babies weighed < 2,500 g compared with 5.2% in France. The rate of perinatal, neonatal, and infant mortality were higher than the national average. The rate of malformation (2.86%) was comparable with national survey (2.08%). The health of children diseased during the whole follow-up was approximately 2%.


CONCLUSIONS
The health of children after 1 year of live is close normal.
Rufat
P
P
Institut National de la Santé et de la Recherche Médicale (INSERM), Bicêtre, France.
Olivennes
F
F
de Mouzon
J
J
Dehan
M
M
Frydman
R
R
D001724:Birth Weight; D000013:Congenital Abnormalities / Q000453:epidemiology; D005260:Female; D005307:Fertilization in Vitro; D005602:France; D005865:Gestational Age; D006304:Health Status; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome