title: Mammary cystosarcoma with mature adipose stromal differentiation (lipophyllodes tumor) arising in a lipomatous hamartoma.
abstract: This report documents an uncommon variant of benign cystosarcoma phyllodes with mature adipose stromal differentiation, for which the term lipophyllodes tumor is proposed. Origin of this unusual tumor within a lipomatous hamartoma was confirmed by histologic and mammographic observations. The lesion developed in a 40-year-old woman 2 months post partum, and she remained well after treatment by biopsy. Lipophyllodes tumor, which features mature adipose tissue in much of the stromal component of a cystosarcoma, should not be mistaken for a malignant neoplasm. Complete excision is adequate therapy.
authors.affiliation: Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021.
authors.forename: P P
authors.initials: PP
authors.lastname: Rosen
authors.forename: K
authors.initials: K
authors.lastname: Romain
authors.forename: L
authors.initials: L
authors.lastname: Liberman
mesh_terms: D000273:Adipose Tissue / Q000473:pathology*; D000328:Adult; D001941:Breast Diseases / Q000150:complications* / Q000473:pathology; D001943:Breast Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*; D002454:Cell Differentiation; D005260:Female; D006222:Hamartoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008327:Mammography; D003557:Phyllodes Tumor / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D017154:Stromal Cells / Q000473:pathology