title: Intratubular spermatic seminoma in a Fischer-344 rat.
abstract: A case of a spontaneous intratubular spermatic seminoma is described in a 98-wk-old Fischer-344 (F-344) rat. The differential diagnosis of spermatic seminoma from the other morphological forms of the tumor was based on the recognition of 3 cell types. The tumor cells were positive for S-100 antigen and cytokeratin. To the best of our knowledge, this is the second case of a seminoma reported in an F-344 rat and the first dealing with electron microscopic and immunohistochemical features of this tumor.
authors.affiliation: Kimron Veterinary Institute, Department of Pathology, Beit Dagan, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Nyska
authors.forename: A
authors.initials: A
authors.lastname: Harmelin
authors.forename: J
authors.initials: J
authors.lastname: Sandbank
authors.forename: M
authors.initials: M
authors.lastname: Scolnik
authors.forename: T
authors.initials: T
authors.lastname: Waner
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D011916:Rats, Inbred F344 / Q000502:physiology*; D018239:Seminoma / Q000737:chemistry* / Q000175:diagnosis / Q000648:ultrastructure*; D013736:Testicular Neoplasms / Q000737:chemistry* / Q000175:diagnosis / Q000648:ultrastructure*