title: [Anticholinesterase activity of certain carboranyl-containing thio- and selenoesters of pentavalent phosphorus acids].
abstract: Anticholinesterase activity of carboranyl containing thio- and selenoesters of pentavalent phosphorus acids has been studied. Insertion of the carboranyl substituents in the thioester group of phosphororganic compounds was found to increase the anticholinesterase activity as compared with the thioalkyl analogues. The compounds with B-carboranyl group are less active inhibitors of cholinesterase than their isomers with C-carboranyl group.
authors.forename: V P
authors.initials: VP
authors.lastname: Balema
authors.forename: E G
authors.initials: EG
authors.lastname: Rys
authors.forename: E E
authors.initials: EE
authors.lastname: Sochilina
authors.forename: O V
authors.initials: OV
authors.lastname: Iagodina
authors.forename: S N
authors.initials: SN
authors.lastname: Moralev
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Zhukovskiĭ
authors.forename: N N
authors.initials: NN
authors.lastname: Godovikov
authors.forename: M I
authors.initials: MI
authors.lastname: Kabachnik
mesh_terms: D000110:Acetylcholinesterase / Q000097:blood; D000818:Animals; D002091:Butyrylcholinesterase / Q000097:blood; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D004952:Esters; D006736:Horses; D006801:Humans; D010757:Phosphorous Acids / Q000737:chemistry / Q000494:pharmacology*; D012643:Selenium / Q000737:chemistry*; D013329:Structure-Activity Relationship; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D002800:Cholinesterase Inhibitors; D004952:Esters; D010757:Phosphorous Acids; D013438:Sulfhydryl Compounds; D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase; D012643:Selenium
vernacular_title: Antikholinésteraznaia aktivnost' nekotorykh karboranilsoderzhashchikh tio- i selenoéfirov kislot piativalentnogo fosfora.