Reactivity of workshop monoclonal antibodies with normal and pathological ovine lymph nodes.
The monoclonal antibodies (82 mAbs) included in the Second Workshop that belonged to agreed named bovine CD and workshop clusters were tested for their reactivity and tissue distribution on (1) normal sheep lymph nodes and (2) pathological sheep lymph nodes. Pathological lymph nodes were induced following experimental infection with Corynebacterium pseudotuberculosis and were characterized by the presence of typical pyogranulomas. Amongst the 82 mAbs tested, 38 reacted with sheep lymph nodes. The results of these tests are presented and discussed.
Pépin
M
M
Laboratoire de Pathologie Infectieuse et Immunologie, INRA-Centre de Recherches de Tours, Nouzilly, France.
Bernard
S
S
Menanteau
P
P
Olivier
M
M
Berthon
P
P
Lantier
F
F
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity / Q000276:immunology; D000937:Antigen-Antibody Reactions / Q000276:immunology; D015703:Antigens, CD / Q000032:analysis; D003354:Corynebacterium Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary; D016925:Corynebacterium pseudotuberculosis / Q000276:immunology; D007124:Immunoenzyme Techniques; D008198:Lymph Nodes / Q000276:immunology*; D008199:Lymphadenitis / Q000276:immunology / Q000382:microbiology / Q000662:veterinary; D008297:Male; D012756:Sheep / Q000276:immunology*; D012757:Sheep Diseases / Q000276:immunology* / Q000382:microbiology
D000911:Antibodies, Monoclonal; D015703:Antigens, CD