Ovulation induction with GnRH agonist and human menopausal gonadotropins: response in patients with one versus two ovaries.
OBJECTIVE
To examine the effect of oophorectomy on response to gonadotropin releasing hormone-agonist/human menopausal gonadotropin (GnRH-a/hMG) for in vitro fertilization (IVF).


METHODS
Retrospective review.


METHODS
Tertiary care academic institution.


METHODS
Ninety-one infertile patients undergoing IVF. Eighty-four women had two ovaries and seven had only one ovary.


RESULTS
There was no difference observed between women with one versus two ovaries with regard to response to medications, hormone production, number of oocytes retrieved and fertilized, or the number of embryos cleaved and transferred.


CONCLUSIONS
Women with only one ovary are at no reproductive disadvantage when undergoing ovulation induction for IVF.
Penzias
A S
AS
Yale University School of Medicine, Department of Obstetrics & Gynecology, New Haven, Connecticut.
Gutmann
J N
JN
Shamma
F N
FN
LaMorte
A I
AI
DeCherney
A H
AH
D000328:Adult; D016009:Chi-Square Distribution; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D016729:Leuprolide / Q000627:therapeutic use*; D017274:Nafarelin / Q000627:therapeutic use*; D010052:Ovariectomy / Q000009:adverse effects; D010053:Ovary / Q000502:physiology*; D010062:Ovulation Induction / Q000379:methods*; D011374:Progesterone / Q000097:blood; D012044:Regression Analysis; D012189:Retrospective Studies
D006063:Chorionic Gonadotropin; D017274:Nafarelin; D011374:Progesterone; D004958:Estradiol; D016729:Leuprolide