title: Minimum views required to characterize cataracts when using the Scheimpflug camera.
abstract: We performed Scheimpflug slit lamp photography and computerized image analysis on 20 normal and 25 cataractous lenses using 18 slit images for each lens taken 10 degrees apart. The data gathered from the normals served as the reference to estimate the accuracy of representation of the cataracts by the least number of views (18 and less) using a Fourier interpolative algorithm. Using the error obtained with one view for the normals, our study suggests that the minimum number of views necessary for adequate characterization is two for cortical cataracts, two for nuclear cataracts, and six for posterior subcapsular cataracts. This information will be useful in longitudinal studies of cataracts, since most researchers presently use only one view, which may be adequate for normals but not for cataractous lenses. We found the Fourier interpolative algorithm useful in estimating the minimum views required for the current method of analyzing Scheimpflug images, and it can be easily applied to other similar images.
authors.affiliation: Cataract and Corneal Diseases Section, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892.
authors.forename: K
authors.initials: K
authors.lastname: Kashima
authors.forename: M
authors.initials: M
authors.lastname: Unser
authors.forename: M B
authors.initials: MB
authors.lastname: Datiles
authors.forename: B L
authors.initials: BL
authors.lastname: Trus
authors.forename: P A
authors.initials: PA
authors.lastname: Edwards
mesh_terms: D000465:Algorithms; D002386:Cataract / Q000473:pathology*; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007908:Lens, Crystalline / Q000473:pathology; D008433:Mathematics; D009885:Ophthalmology / Q000295:instrumentation; D010781:Photography / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results