Synthesis and antitumor activity of LY288601, the 5,6-dihydro analog of LY231514.
Barnett
C J
CJ
Lilly Research Laboratories, A Division of Eli Lilly and Company, Indianapolis, Indiana 46285-4813.
Wilson
T M
TM
Grindey
G B
GB
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D005493:Folic Acid Antagonists / Q000138:chemical synthesis*; D005971:Glutamates / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D006147:Guanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000627:therapeutic use / Q000633:toxicity; D006801:Humans; D019271:Hypoxanthine; D007042:Hypoxanthines / Q000494:pharmacology; D008223:Lymphoma / Q000188:drug therapy; D051379:Mice; D015394:Molecular Structure; D000068437:Pemetrexed; D013329:Structure-Activity Relationship; D013936:Thymidine / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D005493:Folic Acid Antagonists; D005971:Glutamates; D007042:Hypoxanthines; D000068437:Pemetrexed; C085587:LY 288601; D019271:Hypoxanthine; D006147:Guanine; D013936:Thymidine