Asymmetric reflex responses of the nasal and tracheal vasculatures of the dog.
Both sides of the nasal vasculature of the dog in vivo were perfused separately, with measurement of vascular resistance responses to stimulation of various nerves. Stimulation of the central end of a cut superior laryngeal nerve caused an ipsilateral vasodilation (-4.98%) and a contralateral vasoconstriction (+3.96%), the difference being statistically significant (P < 0.01). Stimulation of a glossopharyngeal nerve caused vasodilation on both sides, the ipsilateral (-17.52%) being greater than the contralateral (-6.33%) response (P < 0.05). Mechanical stimulation of the nasal mucosa caused little ipsilateral change (+0.47%) and a weak contralateral vasoconstriction (+3.78%; P < 0.01). Stimulation of the central end of a cervical vagus nerve caused vasodilations on both sides, the ipsilateral (-9.75%) being greater than the contralateral (-5.73%) change (P < 0.05). With bilateral perfusions of the cervical tracheal arteries, stimulation of a superior laryngeal nerve caused vasodilation on both sides, the ipsilateral (-10.1%) being greater than the contralateral (-7.4%) response (P < 0.05). Stimulation of the central end of a vagus nerve caused vasoconstrictions on both the sides, the ipsilateral (+37.4%) being greater than the contralateral (+10.8%) change (P < 0.05). Thus various nervous inputs from the nose, pharynx, larynx, and vagal distribution cause asymmetric vascular responses both in the nose and in the cervical trachea.
Dylewska
K
K
Department of Physiology, St George's Hospital Medical School, London, United Kingdom.
Sahin
G
G
Widdicombe
J G
JG
D000818:Animals; D001794:Blood Pressure / Q000502:physiology; D004285:Dogs; D004558:Electric Stimulation; D005260:Female; D008297:Male; D009296:Nasal Cavity / Q000098:blood supply* / Q000294:innervation; D010812:Physical Stimulation; D012018:Reflex / Q000502:physiology*; D012039:Regional Blood Flow / Q000502:physiology; D014132:Trachea / Q000098:blood supply* / Q000294:innervation; D014655:Vascular Resistance / Q000502:physiology