title: Capillary blood flow velocity measurements in cystoid macular edema with the scanning laser ophthalmoscope.
abstract: Using a scanning laser ophthalmoscope, we calculated the velocity of retinal blood flow in a juxta-foveolar capillary during the course of cystoid macular edema after partial central retinal vein occlusion in a 53-year-old woman. The mean velocity of the fluorescent dots in the macular capillary of the right eye with cystoid macular edema was 1.59 +/- 0.08 mm/sec at the initial examination. Despite the systemic administration of indomethacin (75 mg/day for three weeks), best-corrected visual acuity decreased from 20/30 to 20/70, and the velocity became 0.82 +/- 0.13 mm/sec. Prednisolone (30 mg/day orally for one week) improved the cystoid macular edema, and the velocity was 0.96 +/- 0.06 mm/sec 12 days after initiation of the drug. The velocity gradually improved; one year later it was 1.65 +/- 0.17 mm/sec and visual acuity was 20/22. Velocity in the left eye, which did not have cystoid macular edema, was 2.16 +/- 0.16 mm/sec. Thus, scanning laser ophthalmoscopy proved useful for measuring the velocity of retinal blood flow.
authors.affiliation: Department of Ophthalmology, Kyushu University, Fukuoka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ohnishi
authors.forename: K
authors.initials: K
authors.lastname: Fujisawa
authors.forename: T
authors.initials: T
authors.lastname: Ishibashi
authors.forename: H
authors.initials: H
authors.lastname: Kojima
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D002196:Capillaries / Q000503:physiopathology; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods; D008269:Macular Edema / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000379:methods; D011239:Prednisolone / Q000627:therapeutic use; D012170:Retinal Vein Occlusion / Q000150:complications; D012171:Retinal Vessels / Q000503:physiopathology*; D014792:Visual Acuity
chemical_list: D011239:Prednisolone