[Comparative study of the effect of radiation and other lymphatic agents on lymphoid tissue of dogs and rats: chromatin degradation, DNA and protein synthesis in cells].
It is established that lymphatic tissue of dogs shows far less degradation of chromatin after whob body irradiation (6 Gy) or exposure to lympholytic agents (hydrocortisone and colchicine), compared to rats. The fragmentation of chromatin in dog thymus occurs, like in rat, according to the internucleosome type, but affects a considerably less part of the thymocyte population.
Ermolaeva
N V
NV
Aphonin
A N
AN
Ushenkova
L N
LN
D000818:Animals; D000831:Animals, Newborn; D001853:Bone Marrow / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D002843:Chromatin / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D003078:Colchicine / Q000494:pharmacology*; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects* / Q000528:radiation effects*; D004285:Dogs; D005260:Female; D006854:Hydrocortisone / Q000494:pharmacology*; D008221:Lymphoid Tissue / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D011833:Radiation Injuries, Experimental / Q000378:metabolism; D051381:Rats; D013154:Spleen / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D013950:Thymus Gland / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects
D002843:Chromatin; D004247:DNA; D003078:Colchicine; D006854:Hydrocortisone
Sravnitelńyĭ analiz deĭstviia radiatsii i drugikh lympholiticheskikh agentov na limphoidnuiu tkan sobak i krys: degradatsiia khromatina, sintez DNK i belka v kletkakh.