Exercise and gonadal function.
Exercise is associated with release of a number of pituitary and hypothalamic hormones and a decline in the concentration of luteinizing hormone (LH). Follicle stimulating hormone (FSH) is generally not influenced by exercise. Serum inhibin concentrations, which are reciprocally influenced by serum FSH concentrations, are increased in some animals but are unchanged after acute exercise in human males. Teleologically, the decline in gonadotrophic hormone (LH) secretion after exercise may be geared to enhance individual survival over species propagation in times of stress, analogous to the postulated 'fight or flight' reaction. The decrease in gonadotrophic hormone (LH) secretion is believed to be due to changes in gonadotrophin releasing hormone (GnRH) pulse frequency and amplitude, particularly in women, who often develop amenorrhoea. Males have less dramatic changes in their hypothalamic-pituitary-gonadal axis, although a significant decrease in serum testosterone in physically conditioned males can usually be demonstrated. In this update possible mechanisms for the decline in gonadotrophin secretion with exercise are briefly discussed.
Elias
A N
AN
Department of Medicine, University of California at Irvine 92717.
Wilson
A F
AF
D000818:Animals; D015444:Exercise / Q000502:physiology*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000096:biosynthesis / Q000378:metabolism; D006065:Gonadotropins, Pituitary / Q000378:metabolism; D006801:Humans; D007006:Hypogonadism / Q000503:physiopathology; D008297:Male; D008599:Menstruation Disturbances / Q000503:physiopathology; D010053:Ovary / Q000502:physiology*; D012636:Secretory Rate / Q000502:physiology; D013737:Testis / Q000502:physiology*
D006065:Gonadotropins, Pituitary; D007987:Gonadotropin-Releasing Hormone