Bartter's syndrome in two generations of an Irish family.
We report four cases of Bartter's syndrome in two consecutive generations of an Irish family. Diagnoses were made on the basis of characteristic clinical features, blood and urine biochemistry with additional evidence from renal biopsy in one case. The aetiology, treatment and inheritance of the syndrome are discussed.
Crowe
P
P
Department of Endocrinology and Metabolism, St James's Hospital, Dublin, Ireland.
Ahmad
A
A
O'Byrne
K
K
Cullen
M J
MJ
D000328:Adult; D000450:Aldosterone / Q000097:blood; D001477:Bartter Syndrome / Q000097:blood / Q000188:drug therapy / Q000235:genetics*; D002216:Captopril / Q000627:therapeutic use; D005192:Family Health; D006801:Humans; D007008:Hypokalemia / Q000150:complications; D007494:Ireland; D008274:Magnesium / Q000097:blood; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D011188:Potassium / Q000627:therapeutic use; D012083:Renin / Q000097:blood; D012964:Sodium / Q000097:blood
D000450:Aldosterone; D002216:Captopril; D012964:Sodium; D012083:Renin; D008274:Magnesium; D011188:Potassium