ANCA and anti-GBM antibodies in RPGN.
ANCA and anti-GBM antibodies can occur together in RPGN. These patients are rare and have two distinct populations of antibodies and the ANCA specificity tends to be for myeloperoxidase more often than expected.
Short
A K
AK
Department of Medicine, University of Cambridge, U.K.
Esnault
V L
VL
Lockwood
C M
CM
D000906:Antibodies / Q000097:blood*; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000097:blood*; D001485:Basement Membrane / Q000276:immunology; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D009195:Peroxidase / Q000276:immunology
D000906:Antibodies; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D007074:Immunoglobulin G; C051951:antiglomerular basement membrane antibody; D009195:Peroxidase