title: Affective reactivity of language in schizophrenia.
abstract: Thirty acutely schizophrenic inpatients each provided two speech samples: one on affectively negative, "high-stress" topics and one on affectively positive, "low-stress" topics. We analyzed these using two different, established methods for assessment of deviance in natural language, including clinical measures of thought disorder and linguistic measures of reference performance. For the group as a whole, the speech on negative topics contained more disorder than did the speech on positive topics, as rated both clinically and linguistically, and these differences were sizeable and highly significant. Level of language disturbance and degree of affective reactivity of language symptoms correlated positively with severity of the positive syndrome but were not associated in either direction with negative syndrome severity. Affective reactivity of symptoms is discussed as a variable potentially relevant to studies of psychophysiology and subtyping in schizophrenia.
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519.
authors.forename: N M
authors.initials: NM
authors.lastname: Docherty
authors.forename: I M
authors.initials: IM
authors.lastname: Evans
authors.forename: W H
authors.initials: WH
authors.lastname: Sledge
authors.forename: J P
authors.initials: JP
authors.lastname: Seibyl
authors.forename: J H
authors.initials: JH
authors.lastname: Krystal
mesh_terms: D000328:Adult; D000339:Affect; D005260:Female; D006760:Hospitalization; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D011578:Psycholinguistics; D012559:Schizophrenia / Q000145:classification / Q000175:diagnosis*; D012564:Schizophrenic Language; D012565:Schizophrenic Psychology; D012660:Semantics; D012720:Severity of Illness Index; D013060:Speech