title: [Lipid composition and fertility of human ejaculate].
abstract: The morpho-functional indexes of ejaculates from 35 healthy and 145 infertile men were studied. The depression of functional sperm activity was found in the majority of infertile men. Phospholipid analysis of whole ejaculates from 12 healthy and 35 infertile subjects was performed. It was shown that inorganic phosphorus of total phospholipids decreased in ejaculates of men with secretory infertility. Lyso-phosphatidyl choline (LPC) was not detected in ejaculates of men with relative infertility. The amount of lyso-phosphatidyl ethanolamine (lyso-PE) and sphingomyelin in whole ejaculates of those patients decreased. The levels of LPC and lyso-PE decreased in ejaculates of persons with associated infertility. The level of phosphatidyl inositol, LPC and PE decreased in ejaculates of men with secretory infertility. The gas-lipid chromatography analysis of fatty acids composition of whole ejaculates of the infertile men showed significant changes in quantity of fatty acids. The quantity of docosahexaenoic acid in ejaculates of infertile men decreased and positively correlated with motility of spermatozoa.
authors.forename: N M
authors.initials: NM
authors.lastname: Hula
authors.forename: M D
authors.initials: MD
authors.lastname: Tron'ko
authors.forename: H L
authors.initials: HL
authors.lastname: Volkov
authors.forename: V M
authors.initials: VM
authors.lastname: Marhitych
mesh_terms: D005227:Fatty Acids / Q000032:analysis; D005298:Fertility / Q000502:physiology*; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008244:Lysophosphatidylcholines / Q000032:analysis; D008246:Lysophospholipids / Q000032:analysis; D008297:Male; D010716:Phosphatidylinositols / Q000032:analysis; D010743:Phospholipids / Q000032:analysis; D010758:Phosphorus / Q000032:analysis; D012661:Semen / Q000737:chemistry* / Q000166:cytology
chemical_list: D005227:Fatty Acids; D008055:Lipids; D008244:Lysophosphatidylcholines; D008246:Lysophospholipids; D010716:Phosphatidylinositols; D010743:Phospholipids; C008301:lysophosphatidylethanolamine; D010758:Phosphorus
vernacular_title: Lipidovyĭ sklad ta fertyl'na spromozhnist' liuds'koho eiakuliatu.