title: Napyradiomycins A and B1: non-steroidal estrogen-receptor antagonists produced by a Streptomyces.
authors.affiliation: Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hori
authors.forename: Y
authors.initials: Y
authors.lastname: Abe
authors.forename: N
authors.initials: N
authors.lastname: Shigematsu
authors.forename: T
authors.initials: T
authors.lastname: Goto
authors.forename: M
authors.initials: M
authors.lastname: Okuhara
authors.forename: M
authors.initials: M
authors.lastname: Kohsaka
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003600:Cytosol / Q000187:drug effects / Q000378:metabolism; D005260:Female; D009285:Naphthoquinones / Q000494:pharmacology; D051381:Rats; D011960:Receptors, Estrogen / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013302:Streptomyces / Q000378:metabolism*; D014599:Uterus / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure
chemical_list: D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; D011960:Receptors, Estrogen; C054848:napyradiomycin B1; C054847:napyradiomycin A1; C054262:napyradiomycin A2