Expression of CGRP mRNAs in the pink salmon, Oncorhynchus gorbuscha.
We report the isolation of calcitonin gene-related peptide (CGRP) mRNAs and expression of these RNAs in different tissues in the pink salmon, Oncorhynchus gorbuscha. Hybridization of poly(A+) RNAs indicated a mature CGRP RNA of 1.1 kb. The CGRP-like immunoreactivity occurring in tissues and plasma had the same relative molecular weight as the synthetic molecule. Variations in CGRP plasma levels were observed during migration, spawning, and postspawning states. These data suggest that CGRP may play an important role during the reproductive cycle of salmon.
Maubras
L
L
U.113 INSERM et UA 163 CNRS, Paris, France.
Taboulet
J
J
Pidoux
E
E
Lasmoles
F
F
Julienne
A
A
Milhaud
G
G
Benson
A A
AA
Moukhtar
M S
MS
Cressent
M
M
D000818:Animals; D015152:Blotting, Northern; D015740:Calcitonin Gene-Related Peptide / Q000235:genetics*; D005260:Female; D017683:Oncorhynchus / Q000378:metabolism*; D009928:Organ Specificity / Q000502:physiology; D012333:RNA, Messenger / Q000096:biosynthesis*; D011863:Radioimmunoassay; D012098:Reproduction / Q000502:physiology
D012333:RNA, Messenger; D015740:Calcitonin Gene-Related Peptide