Drugs affecting the hematologic system of the performance horse.
Pharmacologic alterations in the hematologic and rheologic properties of blood may have an important effect on transport and delivery of oxygen to working muscle during exercise. This article briefly reviews erythropoiesis, hematologic and rheologic responses to training and exercise, and the influence of these alterations on exercise performance. The hemorrheologic and performance effects of hematinics, hematopoietic stimulants, and alterations in blood rheology are discussed. The effects of exercise on blood coagulation, fibrinolysis and platelet function, and the effects of drugs that alter platelet function are briefly described.
Geor
R J
RJ
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada.
Weiss
D J
DJ
D000818:Animals; D001773:Blood Cells / Q000187:drug effects*; D001777:Blood Coagulation / Q000187:drug effects; D001792:Blood Platelets / Q000187:drug effects; D001810:Blood Volume / Q000187:drug effects; D004920:Erythropoiesis / Q000187:drug effects*; D005665:Furosemide / Q000494:pharmacology; D006397:Hematinics / Q000494:pharmacology*; D006736:Horses / Q000097:blood*; D010431:Pentoxifylline / Q000494:pharmacology; D010805:Physical Conditioning, Animal; D012212:Rheology
D006397:Hematinics; D005665:Furosemide; D010431:Pentoxifylline