title: Hereditary nephrogenic diabetes insipidus and bilateral nonobstructive hydronephrosis.
abstract: We describe 2 cases of hereditary nephrogenic diabetes insipidus with massive bilateral dilatation of the urinary tract without any organic obstruction. A review of the literature revealed that dilatation of the urinary tract was present in 67% of the reported cases of nephrogenic diabetes insipidus which included a description of the urinary tract. This strong association between hereditary nephrogenic diabetes insipidus and nonobstructive hydronephrosis suggests a cause-and-effect relationship in which polyuria is responsible for the hydronephrosis.
authors.affiliation: Department of Medicine, Mount Sinai Medical Center, New York 10029.
authors.forename: J
authors.initials: J
authors.lastname: Uribarri
authors.forename: M
authors.initials: M
authors.lastname: Kaskas
mesh_terms: D000328:Adult; D003919:Diabetes Insipidus / Q000150:complications* / Q000175:diagnosis / Q000235:genetics*; D004108:Dilatation, Pathologic; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology* / Q000473:pathology; D008297:Male; D011141:Polyuria / Q000150:complications; D014551:Urinary Tract / Q000473:pathology