title: [rhG-CSF treatment in cyclic neutropenia. Continuous versus intermittent rhG-CSF treatment in cyclic neutropenia].
abstract: Cyclic neutropenia is a stem-cell disorder characterized by regular 21-day cyclic fluctuations in the number of neutrophils in the blood and bone marrow. The neutropenic periods may be complicated by fever, stomatitis and severe infections. In this case report only daily continuous and later intermittent treatment with recombinant human granulocyte colony-stimulating factor (two micrograms/kg) administered subcutaneously effectively prevented recurrent infections.
authors.affiliation: Medicinsk haematologisk afdeling L. Københavns Amts Sygehus i Herlev.
authors.forename: H
authors.initials: H
authors.lastname: Nielsen
authors.forename: P B
authors.initials: PB
authors.lastname: Hansen
mesh_terms: D000328:Adult; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000008:administration & dosage*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D009503:Neutropenia / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D010507:Periodicity
chemical_list: D016178:Granulocyte-Macrophage Colony-Stimulating Factor
vernacular_title: rhG-CSF-behandling ved cyklisk neutropeni. Kontinuerlig versus intermitterende rhG-CSF-behandling ved cyklisk neutropeni.