title: Clinical features and MR imaging in children with repaired myelomeningocele.
abstract: The aim of the study is to define the role of associated malformations in the clinical evolution of children affected by myelomeningocele. MRI investigation of the spinal cord was carried out on 25 patients between the age of 7.3 and 18.10 with MMC repaired and followed up for at least 7 years. The relation between associated malformations demonstrated by MRI and clinical trend was analysed. The results are the following: 1) presence of asymptomatic tethered cord in all cases; 2) high frequency (92%) of Chiari malformation; 3) presence of syringomyelia in 20% of patients, symptomatic in 1; 4) presence of ventricular enlargement in 72% of cases without increased intracranial pressure syndrome. For a better therapeutic approach prospective MRI studies are needed in order to follow up associated malformations.
authors.affiliation: Divisione Neurologia dello Sviluppo, Istituto Nazionale Neurologico C. Besta, Milano.
authors.forename: R
authors.initials: R
authors.lastname: Bono
authors.forename: M
authors.initials: M
authors.lastname: Inverno
authors.forename: G
authors.initials: G
authors.lastname: Botteon
authors.forename: M G
authors.initials: MG
authors.lastname: Bruzzone
authors.forename: M A
authors.initials: MA
authors.lastname: Vaghi
authors.forename: C L
authors.initials: CL
authors.lastname: Solero
authors.forename: E
authors.initials: E
authors.lastname: Perlasca
authors.forename: E
authors.initials: E
authors.lastname: Fedrizzi
mesh_terms: D000293:Adolescent; D002552:Cerebral Ventricles / Q000473:pathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008591:Meningomyelocele / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D011184:Postoperative Period; D013116:Spinal Cord / Q000002:abnormalities / Q000473:pathology / Q000503:physiopathology