Quantitative analysis of bone metastasis in prostate cancer.
A new method of quantitative analysis of bone metastasis in prostate cancer is described. By using a variance-dependent filter and a smoothing filter, the increased uptake lesions were distinctly demonstrated on the bone scintigraphy. The images were divided into several areas and analyzed. These procedures resulted in a clear identification of the metastatic lesions. Repeated measurements of the metastatic areas from the same scintigrams disclosed a high reproducibility. This method appears to be highly consistent and clinically applicable.
Kubota
Y
Y
Department of Urology, Yamagata University School of Medicine, Japan.
Nakada
T
T
Sasagawa
I
I
Izumiya
K
K
D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*; D011877:Radionuclide Imaging; D015203:Reproducibility of Results