title: [Comparative evaluation of dipyridamole and dobutamine 2-dimensional echocardiography in ischemic heart disease].
abstract: Dipyridamole and dobutamine stress were performed in the same 41 angiographically controlled patients. Both tests were followed by 2 dimensional-echocardiography. The dose of dipyridamole was 0.56 mg/kg/4 min. or 0.84 mg/kg over 10 min., while the dose of dobutamine was 10-20-30-40 and 40 micrograms/kg/min. over 3 min. each step. In addition, to reach the submaximal heart rate 0.25 mg/min Atropine was also injected for 4 minutes in 13 cases. One vessel disease was found in 15 cases, and 2 vessel disease was in 2 cases. The number of coronarography negative cases was 24. The sensitivity, specificity, positive and negative predictive values for both tests were 70%, 91%, 85% and 81%, respectively. False positive results were observed in 2 cases and false negative ones were found in 5 cases, mainly at left anterior descendent stenosis. There was a good agreement between the wall motion abnormality and the anatomic localization of stenoses. Both non-invasive tests are suitable for the diagnosis of ischaemic heart disease.
authors.affiliation: Szent-Györgyi Albert Orvostudományi Egyetem, II. Belgyógyászati Klinika, Szeged.
authors.forename: N
authors.initials: N
authors.lastname: Gruber
authors.forename: A
authors.initials: A
authors.lastname: Varga
authors.forename: T
authors.initials: T
authors.lastname: Forster
authors.forename: L
authors.initials: L
authors.lastname: Varga
authors.forename: A
authors.initials: A
authors.lastname: Borthaiser
authors.forename: M
authors.initials: M
authors.lastname: Csanády
mesh_terms: D000328:Adult; D000368:Aged; D004176:Dipyridamole; D004280:Dobutamine; D004341:Drug Evaluation; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis*; D011237:Predictive Value of Tests
chemical_list: D004280:Dobutamine; D004176:Dipyridamole
vernacular_title: Dipyridamol és dobutamin terheléses 2 dimenziós echocardiographia összehasonlító értékelése ischaemiás szívbetegségben.