title: Dynamic echography of the penis in the follow-up of impotent patients treated with intracavernous injections.
abstract: Dynamic echography of the penis (DEP) after pharmacological stimulation of erection has been designed to evaluate the albugineal wall thickness (AWT), the cavernosal appearance in the normal penis and corporeal changes in patients treated with intracavernous injections presenting with haematomata, hyperechoic images, prolonged erection and Peyronie's disease. DEP was performed in 973 patients who had had an average number of 89 (+/- 16) intracavernous injections for 16.7 +/- 11.7 months. A total of 1424 DEP examinations were performed. Transducer positioning, erectile condition, clinical recording and computer retrieval methods were adapted to gather ultrasonography data. The standard average AWTs recorded in patients free from Peyronie's disease and who were untreated were 0.11 cm at the septum, 0.17 and 0.15 cm at the dorsal root and the tip of the albuginea respectively, 0.14 cm ventrally and the diameter of the corpus cavernosum averaged 1.61 cm. Intracavernous therapy brought an increase in AWT of 15.38% to the septum, 11.76% and 10.53% to the dorsal tip and root respectively and 12.5% ventrally. Frequent haematomata induced greater increase, while prolonged erections did not. Patients with untreated Peyronie's disease were found to have greater AWT which decreased after treatment with intracavernosal injections. Before treatment abnormal penile hyperechoic images were found in 3.18% (intracavernous images) and 3.31% (albugineal nodules) of DEP, and in 7.09% and 7.54% respectively post-treatment.
authors.affiliation: Centre d'Etudes et de Recherche de l'Impuissance, Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Virag
authors.forename: F
authors.initials: F
authors.lastname: Nollet
authors.forename: E
authors.initials: E
authors.lastname: Greco
authors.forename: K
authors.initials: K
authors.lastname: Shoukry
mesh_terms: D007172:Erectile Dysfunction / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D010410:Penile Erection / Q000187:drug effects / Q000502:physiology; D010411:Penile Induration / Q000000981:diagnostic imaging / Q000473:pathology; D010413:Penis / Q000000981:diagnostic imaging* / Q000473:pathology; D011446:Prospective Studies; D014463:Ultrasonography; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D014662:Vasoconstrictor Agents