Clinical features of Kleine-Levin syndrome with localized encephalitis.
We report the clinico-pathological findings regarding a 9 year-old girl with some clinical features of Kleine-Levin syndrome who died suddently as a result of pulmonary embolism in the course of femoro-iliac thrombophlebitis. Neuropathological examination provided evidence of perivascular inflammatory infiltrates and microglial proliferation of nodular type located in the diencephalon and midbrain. These findings suggest that a localized encephalitis may be the underlying condition in Kleine-Levin syndrome.
Fenzi
F
F
Istituto di Neurologia, Universita di Verona, Italy.
Simonati
A
A
Crosato
F
F
Ghersini
L
L
Rizzuto
N
N
D001931:Brain Mapping; D002648:Child; D003645:Death, Sudden / Q000473:pathology; D004660:Encephalitis / Q000473:pathology*; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000473:pathology; D007124:Immunoenzyme Techniques; D017593:Kleine-Levin Syndrome / Q000473:pathology*; D008636:Mesencephalon / Q000473:pathology; D009457:Neuroglia / Q000473:pathology; D011655:Pulmonary Embolism / Q000473:pathology; D013787:Thalamic Nuclei / Q000473:pathology