[Lead: histopathological findings in experimental contamination].
The aim of the present paper is to show lead toxicity and cell deposition of concentrations lower than those regarded as toxic on an experimental model with rats C3Hs., forty five grams-rats were used. A standard diet was administered together with water ad-libitium, containing very low doses of lead acetate which was constantly administered and at fixed periods. Light and electron microscopy were used to study the liver and the spleen. These organs are considered to harbour a great amount of constant macrophages with phagocytic function. The findings showed lesions and lead deposits which confirmed the causative agent as well as its toxic contaminating action.
Riera de Martínez Villa
N
N
Cátedra de Toxicología, Facultad de Medicina, Universidad Nacional de Tucumán, San Miguel de Tucumán, Argentina.
Torres de Mercau
G
G
Martínez Riera
N
N
Soria de Santos
N
N
Vitalone
H
H
D000818:Animals; D007855:Lead Poisoning / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D051379:Mice; D008809:Mice, Inbred C3H; D013154:Spleen / Q000473:pathology*
Plomo: hallazgos histopatológicos en contaminación experimental.