[A study on P21(ras) in human lung cancer and body fluid of cancer patients].
The McAb of anti-P21(ras) has been used to screen 9 cases of human lung cancer tissues, 18 cases of samples and 2 cases of hydrothorax samples of lung cancer patients by means of PAGE-immunoblots. The expression of ras gene was found in 8 cases of human lung cancer among which the expression of 4 cases was higher than that of normal control. P21(ras) has not been detected in serum and hydrothorax samples of cancer patients. The present study indicated that there was P21(ras) in human lung cancer and normal control and the expression level of ras gene in lung cancer was related to the differentiation of cancer.
Lin
X
X
Shu
X
X
Sun
Z
Z
Zhao
J
J
Sun
Z
Z
D000230:Adenocarcinoma / Q000235:genetics* / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000378:metabolism; D005122:Exudates and Transudates / Q000378:metabolism; D015870:Gene Expression; D011905:Genes, ras; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics* / Q000378:metabolism; D016283:Proto-Oncogene Proteins p21(ras) / Q000096:biosynthesis*
C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras)