Mechanisms and control of repolarization.
This paper describes and discusses interventions that may lead to prolongation of the action potential. Special emphasis is given to regulation by drugs. The results of studies focusing on the modulation of inward and outward currents are presented in detail. Specific attention is given to Na+, Ca2+, K+ and Cl- channel currents and their components.
Carmeliet
E
E
University of Leuven, Belgium.
D000200:Action Potentials / Q000187:drug effects / Q000502:physiology; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D015220:Calcium Channels / Q000187:drug effects / Q000502:physiology; D018118:Chloride Channels / Q000187:drug effects / Q000502:physiology; D006329:Heart Conduction System / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D015221:Potassium Channels / Q000187:drug effects / Q000502:physiology; D015222:Sodium Channels / Q000187:drug effects / Q000502:physiology
D000889:Anti-Arrhythmia Agents; D015220:Calcium Channels; D018118:Chloride Channels; D015221:Potassium Channels; D015222:Sodium Channels