Approach to the chemotopography of the digitalis recognition matrix in Na+/K(+)-transporting ATPase as a step in the rational design of new inotropic steroids.
Repke
K R
KR
Energy Conversion Unit, Max Delbrück Centre for Molecular Medicine, Berlin-Buch, Germany.
Weiland
J
J
Megges
R
R
Schön
R
R
D000818:Animals; D002316:Cardiotonic Agents / Q000138:chemical synthesis / Q000737:chemistry*; D004195:Disease Models, Animal; D015195:Drug Design; D006801:Humans; D000254:Sodium-Potassium-Exchanging ATPase / Q000737:chemistry*
D002316:Cardiotonic Agents; C027082:digitalis receptor; D000254:Sodium-Potassium-Exchanging ATPase