Effects of folic acid on pyrimethamine teratogenesis in rats.
Kudo
G
G
Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan.
Tsunematsu
K
K
Shimoda
M
M
Kokue
E
E
D000014:Abnormalities, Drug-Induced / Q000517:prevention & control; D000284:Administration, Oral; D000818:Animals; D004357:Drug Synergism; D004622:Embryo, Mammalian / Q000187:drug effects; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage / Q000494:pharmacology* / Q000633:toxicity; D007274:Injections, Intraperitoneal; D002955:Leucovorin / Q000008:administration & dosage / Q000494:pharmacology* / Q000633:toxicity; D051379:Mice; D008813:Mice, Inbred ICR; D011247:Pregnancy; D011739:Pyrimethamine / Q000493:pharmacokinetics / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D013723:Teratogens / Q000493:pharmacokinetics / Q000633:toxicity*
D013723:Teratogens; D005492:Folic Acid; D002955:Leucovorin; D011739:Pyrimethamine