Mycophenolic acid simultaneously reduces intracellular GTP and tetrahydrobiopterin levels in neuro-2A cells.
Harada
T
T
Department of Medical Chemistry, Osaka Medical College, Japan.
Hatakeyama
K
K
Kagamiyama
H
H
D000429:Alcohol Oxidoreductases / Q000378:metabolism; D000818:Animals; D001708:Biopterins / Q000031:analogs & derivatives* / Q000378:metabolism; D002460:Cell Line; D004093:Dihydropteridine Reductase / Q000378:metabolism; D006136:GTP Cyclohydrolase / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism* / Q000494:pharmacology; D007700:Kinetics; D051379:Mice; D009173:Mycophenolic Acid / Q000494:pharmacology*; D009447:Neuroblastoma / Q000378:metabolism*; D019761:Phosphorus-Oxygen Lyases; D014407:Tumor Cells, Cultured
D001708:Biopterins; D006160:Guanosine Triphosphate; D000429:Alcohol Oxidoreductases; C022630:sepiapterin reductase; D004093:Dihydropteridine Reductase; D006136:GTP Cyclohydrolase; D019761:Phosphorus-Oxygen Lyases; C043497:6-pyruvoyltetrahydropterin synthase; C003402:sapropterin; D009173:Mycophenolic Acid