Inhibitors of sterol biosynthesis and their applications.
Mercer
E I
EI
Department of Biochemistry, University of Wales, Aberystwyth, Dyfed, U.K.
D000818:Animals; D065607:Cytochrome P-450 Enzyme Inhibitors; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors; D005658:Fungi / Q000378:metabolism; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D019751:Intramolecular Transferases; D007535:Isomerases / Q000037:antagonists & inhibitors; D007810:Lanosterol / Q000037:antagonists & inhibitors; D008780:Methyltransferases / Q000037:antagonists & inhibitors; D009097:Multienzyme Complexes; D010088:Oxidoreductases / Q000037:antagonists & inhibitors; D010105:Oxygenases / Q000037:antagonists & inhibitors; D010944:Plants / Q000378:metabolism; D013185:Squalene / Q000378:metabolism; D050603:Squalene Monooxygenase; D058886:Sterol 14-Demethylase; D013261:Sterols / Q000096:biosynthesis*
C548418:CYP51A1 protein, human; D065607:Cytochrome P-450 Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D009097:Multienzyme Complexes; D013261:Sterols; D007810:Lanosterol; C023939:4-methyl sterol demethylase; D013185:Squalene; D010088:Oxidoreductases; D010105:Oxygenases; D058886:Sterol 14-Demethylase; D050603:Squalene Monooxygenase; D008780:Methyltransferases; C022670:delta 24-sterol methyltransferase; D013186:Farnesyl-Diphosphate Farnesyltransferase; D007535:Isomerases; D019751:Intramolecular Transferases; C021924:lanosterol synthase