Correlations between abnormalities on brain SPECT scan and interictal EEG-foci in children with 'intractable' partial epilepsy.
SPECT scanning with Tc99mHM-PAO was performed on 40 children with 'intractable' partial epilepsy; 27 patients had abnormalities on SPECT images consisting of areas of decreased cerebral blood flow. In 18 of these 27 subjects there was a good correlation between site of the abnormalities on SPECT scan and interictal EEG foci. 12 patients with regionally decreased CBF had also neuroimaging (C.T. and/or R.M.I.) abnormalities. The brain SPECT provides more precise detection of epileptogenic foci, when used to complement EEG, also in childhood-onset epilepsy.
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Sez. Aut. Neuropsichiatria Infantile, Ospedali Riuniti di Foggia-U.S.L.
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D000293:Adolescent; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001931:Brain Mapping; D002560:Cerebrovascular Circulation; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D012039:Regional Blood Flow; D015899:Tomography, Emission-Computed, Single-Photon