Pregnancy rates in donors versus recipients according to the serum progesterone level at the time of human chorionic gonadotropin in a shared oocyte program.
Previous data suggested a subtle increase in serum P at the time of hCG injection without LH surge reduces the PR of women having oocyte retrievals for IVF; this study compared PRs of recipients in a shared oocyte program according to the donors' pre-hCG P level. There was no difference in viable PRs between recipients and donors when P < or = 1 ng/mL. The PR was similar for recipients when donors' P was > 1 ng/mL (12.7%). Donors with P > 1 ng/mL had the lowest PR: 7.2%. The data suggest that the adverse effect of higher serum P without LH surge may be on the endometrium rather than the oocyte.
Check
J H
JH
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Department of Obstetrics and Gynecology, Cooper Hospital/University Medical Center, Camden.
Hourani
C
C
Choe
J K
JK
Callan
C
C
Adelson
H G
HG
D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D009865:Oocytes; D011247:Pregnancy; D011374:Progesterone / Q000097:blood*; D014019:Tissue Donors
D006063:Chorionic Gonadotropin; D011374:Progesterone