title: Pseudomonas septicemia in infants and children: a retrospective analysis of 49 cases.
abstract: Reviewed 49 cases of Pseudomonas bacteremia which occurred in pediatric patients during an 8-year period showed the annual rate, per 1000 discharges, was 1.7. In most of the patients (73.5%), the disease was hospital-acquired. Male to female distribution was about 3 to 2. The average age of the 49 patients was 1.29 years, and 55.1% were infected at less than 2 months old. Overall mortality was 44.9%; among the mortalities, 63.6% were under two months of age. Clinical features were not characteristic, but the most common sign associated with this infection was fever (42.9%). Ecthyma gangrenosum occurred in only one patient. Respiratory tract and skin were the most frequent sources of the bacteremia. Polymicrobial bacteremia occurred in 18.4%. Patients with shock, pneumonia, inadequate antibiotic therapy or persistent neutropenia had a substantially poorer prognosis. Administration of combination therapy to patients with Pseudomonas bacteremia seemed to be superior to monotherapy for positive outcome.
authors.affiliation: Section of Pediatrics, Veterans General Hospital-Taichung, Taiwan, R.O.C.
authors.forename: T M
authors.initials: TM
authors.lastname: Wang
authors.forename: S C
authors.initials: SC
authors.lastname: Chen
authors.forename: W J
authors.initials: WJ
authors.lastname: Shian
authors.forename: C H
authors.initials: CH
authors.lastname: Chen
authors.forename: C S
authors.initials: CS
authors.lastname: Chi
mesh_terms: D000293:Adolescent; D016470:Bacteremia / Q000453:epidemiology* / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology / Q000401:mortality; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011552:Pseudomonas Infections / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D013624:Taiwan / Q000453:epidemiology