[Use of cholinesterase inhibitors in Alzheimer disease].
According to the cholinergic theory of Alzheimer's disease, the cognitive failure depends on a deficit in acetylcholine. The study reported above examines the efficacy and tolerability of cholinesterase inhibitors, such as tetrahydroamino acridine (THA), for the management of this pathology.
Sampalmieri
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M
II Divisione di Geriatria, Ospedale dell'Addolorata di Roma.
Troiani
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MP
Servi
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M
D000109:Acetylcholine / Q000172:deficiency*; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism; D002800:Cholinesterase Inhibitors / Q000008:administration & dosage*; D003072:Cognition Disorders / Q000188:drug therapy / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D013619:Tacrine / Q000008:administration & dosage*
D002800:Cholinesterase Inhibitors; D013619:Tacrine; D000109:Acetylcholine
Impiego degli inibitori della colinesterasi nella malattia di Alzheimer.