title: Antenatal cystic fibrosis carrier screening--whether, when and how?
abstract: Population screening for carriers of cystic fibrosis (CF) is now possible. Such screening may have both advantages and disadvantages and hence must be evaluated before it becomes routine practice. As the potential benefits of screening are wide and the drawbacks may include psychological effects, a combination of approaches is needed to assess screening thoroughly instead of only counting numbers of terminations or carrier tests. We describe the issues concerned and our methodology for a rigorous evaluation of population antenatal carrier screening for cystic fibrosis.
authors.affiliation: University of Aberdeen, Department of Medical Genetics, Foresterhill, UK.
authors.forename: Z
authors.initials: Z
authors.lastname: Miedzybrodzka
authors.forename: N
authors.initials: N
authors.lastname: Haites
authors.forename: M
authors.initials: M
authors.lastname: Hall
authors.forename: A
authors.initials: A
authors.lastname: Templeton
authors.forename: T
authors.initials: T
authors.lastname: Marteau
authors.forename: J
authors.initials: J
authors.lastname: Dean
authors.forename: K
authors.initials: K
authors.lastname: Kelly
authors.forename: I
authors.initials: I
authors.lastname: Russell
mesh_terms: D001007:Anxiety; D001294:Attitude to Health; D003376:Counseling; D003550:Cystic Fibrosis / Q000175:diagnosis*; D030881:Disclosure; D005820:Genetic Testing / Q000523:psychology; D006579:Heterozygote; D006801:Humans; D010290:Parents / Q000523:psychology; D037841:Pregnant People; D011897:Random Allocation; D006113:United Kingdom