title: [Is it safe and available to transfuse directly the shed mediastinal blood after cardiac surgery?].
abstract: Autotransfusion of the shed mediastinal blood after cardiac operations was performed in 20 cases (ATS group). Safety and efficacy of the autotransfusion were studied comparing with the 10 cases without autotransfusion (control group). A 65.1 +/- 17.1% of bleeding volume within 24 hours after surgery was autotransfused in the ATS group. The ATS group received 1,396 +/- 1,674 ml of the banked blood compared with 780 +/- 1,194 ml for the control group. There was no significant difference between two groups in regard to saving the banked blood. Hematological and biochemical studies after surgery in the ATS and control groups revealed that CPK, BUN and creatinine of the ATS group were significantly higher than those of the control group, although these changes were transitory and trivial. However, prothrombin time of the ATS group was lower than that of control group, so there may be the possibility that this technique itself increases the hemorrhage. Since the cardiotomy filter was obstructed with clots in cases of massive bleeding, shed mediastinal blood may not be fully defibrinogenated in the cases with massive bleeding. These results lead to the following conclusions: autotransfusion of the shed mediastinal blood after cardiac operations is a safe method, but the efficacy of it is doubtful.
authors.affiliation: First Department of Surgery, Kagawa Medical School, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Imawaki
authors.forename: H
authors.initials: H
authors.lastname: Maeta
authors.forename: Y
authors.initials: Y
authors.lastname: Shiraishi
authors.forename: I
authors.initials: I
authors.lastname: Arioka
authors.forename: T
authors.initials: T
authors.lastname: Ugawa
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D000368:Aged; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001803:Blood Transfusion; D001804:Blood Transfusion, Autologous / Q000295:instrumentation / Q000379:methods; D006348:Cardiac Surgical Procedures; D006801:Humans; D008482:Mediastinum; D008875:Middle Aged; D011517:Prothrombin Time