title: Bioactive compounds from the buds of Platanus orientalis and isolation of a new kaempferol glycoside.
abstract: A new compound kaempferol 3-O-alpha-L-(2"-E-p-coumaroyl)-rhamnopyranoside, as well as the known flavonoids, kaempferol 3-O-beta-D-(6"-E-p-coumaroyl)-glucopyranoside, kaempferol 3-O-alpha-L-(2",3"-di-E-p-coumaroyl)-rhamnopyranoside, and caffeic acid were obtained from the methanolic extract of Platanus orientalis L. buds. All the compounds were isolated by column chromatography and identified using 1H-NMR, 2D-1H-NMR (COSY), 1H-13C-NMR, and CIDMS techniques. Cytotoxic and antimicrobial studies were carried out in vitro against human cell lines and against Gram-positive and Gram-negative organisms.
authors.affiliation: Department of Pharmacy, University Campus Zografou, Athens, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Mitrokotsa
authors.forename: S
authors.initials: S
authors.lastname: Mitaku
authors.forename: C
authors.initials: C
authors.lastname: Demetzos
authors.forename: C
authors.initials: C
authors.lastname: Harvala
authors.forename: A
authors.initials: A
authors.lastname: Mentis
authors.forename: S
authors.initials: S
authors.lastname: Perez
authors.forename: D
authors.initials: D
authors.lastname: Kokkinopoulos
mesh_terms: D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002460:Cell Line; D005419:Flavonoids; D006027:Glycosides / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D044949:Kaempferols; D011794:Quercetin / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D014197:Trees / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D005419:Flavonoids; D006027:Glycosides; D044949:Kaempferols; C006552:kaempferol; D011794:Quercetin