Implementation of a model for estimating tumor control probability for an inhomogeneously irradiated tumor.
This paper presents the details of a practical implementation of a model for the prediction of the tumor control probability (TCP) when a tumor is irradiated non-uniformly. The implementation is based on a previously published model and represents a simplified version of the model with a limited number (five) of parameters. We show how to derive the model parameters from clinically available data and offer pseudocode for computer implementation. The model should be a useful tool for evaluating and optimizing 3D dose distributions.
Niemierko
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A
Department of Radiation Oncology, Massachusetts General Hospital, Boston 02114.
Goitein
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M
D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D009369:Neoplasms / Q000532:radiotherapy*; D011336:Probability; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted