Spinal cord blood flow changes during the sleep-wake cycle in rat.
Regional spinal cord blood flow was measured in rats during the sleep-wake cycle with the use of radioactive microspheres. Spinal cord blood flow decreases from wakefulness to quiet (synchronized) sleep while increasing in active (desynchronized) sleep. Blood-flow changes depend on changes in vascular resistance whose mechanisms have yet to be elucidated. Blood-gas tension or mean arterial pressure, however, do not play a relevant causal role.
Zoccoli
G
G
Institute of Human Physiology, University of Bologna, Italy.
Bach
V
V
Nardo
B
B
Cianci
T
T
Lenzi
P
P
Franzini
C
C
D000818:Animals; D001794:Blood Pressure; D003037:Cobalt Radioisotopes; D004569:Electroencephalography; D004576:Electromyography; D006339:Heart Rate; D008297:Male; D008863:Microspheres; D011868:Radioisotopes; D051381:Rats; D017207:Rats, Sprague-Dawley; D012039:Regional Blood Flow; D012890:Sleep / Q000502:physiology*; D013116:Spinal Cord / Q000098:blood supply* / Q000502:physiology; D013324:Strontium; D014001:Tin; D014655:Vascular Resistance; D014851:Wakefulness / Q000502:physiology*
D003037:Cobalt Radioisotopes; D011868:Radioisotopes; D014001:Tin; D013324:Strontium