Ergotamine-induced fetal stress: review of side effects of ergot alkaloids during pregnancy.
A case of sudden fetal stress after accidental administration of ergotamine tartrate (2 mg) suppository is reported. Caesarean section was performed because of unexplained fetal stress. In retrospect, we conclude that it is likely that sudden fetal stress was caused by the severe vasoconstrictive effect of ergotamine. The side effects of ergot derivatives during pregnancy are discussed.
de Groot
A N
AN
Department of Obstetrics and Gynaecology, University Hospital Nijmegen Sint Radboud, The Netherlands.
van Dongen
P W
PW
van Roosmalen
J
J
Eskes
T K
TK
D000328:Adult; D004878:Ergotamine / Q000009:adverse effects*; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced*; D005317:Fetal Growth Retardation; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013610:Tachycardia / Q000139:chemically induced; D014661:Vasoconstriction / Q000187:drug effects
D004878:Ergotamine