title: False DNA aneuploidy in canine and human neoplasms.
abstract: In most cases, the appearance of aneuploid peaks in DNA histograms may be an artefact of tissue preparation or it may reflect non-stoichiometric dye binding of a cellular subpopulation rather than true DNA aneuploidy. This report reviews how false DNA aneuploidy can be recognized and eliminated from sample submitted for DNA flow cytometric analysis.
authors.affiliation: Department of Urology, University of California, Davis 95817.
authors.forename: A D
authors.initials: AD
authors.lastname: Deitch
authors.forename: R W
authors.initials: RW
authors.lastname: de Vere White
authors.forename: B R
authors.initials: BR
authors.lastname: Madewell
mesh_terms: D000782:Aneuploidy; D000818:Animals; D004273:DNA, Neoplasm / Q000032:analysis* / Q000235:genetics; D004283:Dog Diseases; D004285:Dogs; D005189:False Positive Reactions; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D009369:Neoplasms / Q000737:chemistry* / Q000235:genetics / Q000662:veterinary*
chemical_list: D004273:DNA, Neoplasm