Dermatitis herpetiformis and established coeliac disease.
Fifteen (5.3%) of 282 patients with dermatitis herpetiformis (DH) were diagnosed as suffering from coeliac disease before the onset of their DH. This group showed a female preponderance, and a later than usual onset of DH. The mean age at which DH developed was 40.0 years, and there was a mean interval of 13.2 years between the two diagnoses. Seven patients had stopped their gluten-free diet, and a further four were poor compliers. Persistent gluten ingestion in coeliacs with a specific genetic predisposition may result in the development of DH.
Gawkrodger
D J
DJ
University Department of Medicine, Royal Hallamshire Hospital, Sheffield, U.K.
Vestey
J P
JP
O'Mahony
S
S
Marks
J M
JM
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D002446:Celiac Disease / Q000150:complications* / Q000178:diet therapy; D002675:Child, Preschool; D003874:Dermatitis Herpetiformis / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D012737:Sex Factors