title: Suxamethonium-induced muscle pains are not related to cholinesterase activity.
abstract: We have investigated the possibility of using the pre-operative measurement of cholinesterase activity to predict the postoperative development of myalgia following the administration of suxamethonium. Seventy-seven patients presenting for elective extraction of wisdom teeth were entered in the study. All patients received a standard anaesthetic regimen, including suxamethonium to facilitate tracheal intubation, and standardised postoperative analgesia. Myalgia was assessed postoperatively and no correlation between muscle pains and cholinesterase activity was found.
authors.affiliation: Nuffield Department of Anaesthetics, Oxford.
authors.forename: J M
authors.initials: JM
authors.lastname: Ansermino
authors.forename: M A
authors.initials: MA
authors.lastname: Burke
authors.forename: P M
authors.initials: PM
authors.lastname: Upton
authors.forename: J
authors.initials: J
authors.lastname: McVittie
authors.forename: C E
authors.initials: CE
authors.lastname: Blogg
mesh_terms: D000328:Adult; D002802:Cholinesterases / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008964:Molar, Third; D009135:Muscular Diseases / Q000097:blood / Q000139:chemically induced*; D010149:Postoperative Pain / Q000097:blood / Q000139:chemically induced*; D013390:Succinylcholine / Q000009:adverse effects*; D014081:Tooth Extraction
chemical_list: D002802:Cholinesterases; D013390:Succinylcholine