title: Duodenal manometry in postobstructive enteropathy in infants with a transient enterostomy.
abstract: Intestinal motility was studied in 11 children with a transient enterostomy secondary to a neonatal organic small intestine obstruction (5 total colon Hirschsprung's disease, 2 necrotizing enterocolitis, 1 intussusception, 3 ileal atresia). Eight children presented with a postobstructive enteropathy (severe grade I [5], moderate grade II [3]) and three were considered as controls (grade III). They were assigned to one of the three groups on the basis of the duration of parenteral nutrition and constant rate enteral nutrition needed and the oral feeding tolerance. Barium small intestine transit showed no persistent partial obstruction or peritoneal adhesions. The abnormal inert marker transit times were statistically correlated with the clinical groups as well as duodenal manometric abnormalities. Manometric recordings were characterised by the absence (grade I) or abnormal phase III (grade II) of the migrating motor complex and decreased motility index (grades I and II). This study confirms that this enteropathy is due to a chronic alteration in motility induced by prenatal or postnatal obstructions.
authors.affiliation: Service de Gastroentérologie Pédiatrique et de Chirurgie, Hôpital Robert Debre, Paris, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Cezard
authors.forename: G
authors.initials: G
authors.lastname: Cargill
authors.forename: C
authors.initials: C
authors.lastname: Faure
authors.forename: N
authors.initials: N
authors.lastname: Boige
authors.forename: L M
authors.initials: LM
authors.lastname: Mashako
authors.forename: A
authors.initials: A
authors.lastname: Munck
authors.forename: Y
authors.initials: Y
authors.lastname: Aigrain
authors.forename: J
authors.initials: J
authors.lastname: Navarro
mesh_terms: D001466:Barium Sulfate; D016022:Case-Control Studies; D004386:Duodenum / Q000503:physiopathology*; D004750:Enteral Nutrition; D004766:Enterostomy; D005769:Gastrointestinal Motility; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000151:congenital / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D008365:Manometry / Q000379:methods*; D010288:Parenteral Nutrition; D011184:Postoperative Period; D012720:Severity of Illness Index; D013997:Time Factors
chemical_list: D001466:Barium Sulfate