title: Frequent amplification of a short chain dehydrogenase gene in methotrexate resistant Leishmania.
authors.affiliation: Département de Microbiologie, Université Laval, Québec, Canada.
authors.forename: B
authors.initials: B
authors.lastname: Papadopoulou
authors.forename: M
authors.initials: M
authors.lastname: Ouellette
mesh_terms: D000818:Animals; D004351:Drug Resistance / Q000235:genetics; D005784:Gene Amplification; D017125:Genes, Protozoan; D007891:Leishmania / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D008727:Methotrexate / Q000378:metabolism / Q000633:toxicity*; D010088:Oxidoreductases / Q000235:genetics*; D014162:Transfection
chemical_list: D010088:Oxidoreductases; C085592:pteridine reductase; D008727:Methotrexate