[Comparison between ELISA and culture method for detection of Helicobacter pylori].
Detection of Helicobacter pylori (H. pylori) by ELISA was compared with that by the culture method in 115 patients with gastroduodenal diseases. Both the sensitivity and specificity were more than 85% for patients with histological gastritis with neutrophil infiltration. This indicated that the detection of H. pylori by ELISA is useful for the diagnosis of H. pylori-related gastritis. Although the sensitivity between the ELISA and culture method was 85%, the specificity was 58.8%. The false negative detection may have been caused by a sampling error during the endoscopic biopsy.
Takagi
A
A
Department of Gastroenterology, Shiga Medical Center for Adult Disease, Moriyama.
Suyama
T
T
Kida
M
M
Matsuda
M
M
Matsumoto
H
H
Kojima
K
K
Taniyama
K
K
Miyoshi
A
A
D000328:Adult; D000368:Aged; D001431:Bacteriological Techniques; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005756:Gastritis / Q000382:microbiology; D016481:Helicobacter Infections / Q000382:microbiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity