Animal models for radiolabeled monoclonal antibodies in cancer research.
A review of the different animal tumor model systems used for radiolabeled monoclonal antibody research is given. Problems within the field of radioimmunotargeting are presented, and the tumor models are discussed in relation to the types of problems which can be investigated, and the ability of the models to answer different questions.
Aas
M
M
Department of Nuclear Medicine, Norwegian Radium Hospital, Oslo.
Fjeld
J G
JG
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D004195:Disease Models, Animal; D006801:Humans; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D009374:Neoplasms, Experimental; D016719:Radioimmunodetection; D016499:Radioimmunotherapy; D011868:Radioisotopes / Q000627:therapeutic use
D000911:Antibodies, Monoclonal; D011868:Radioisotopes