A case of central diabetes insipidus with spontaneous remission after 8 years of the disease.
A 55-year-old male smoker developed polyuria and polydipsia in November 1983. A water deprivation study revealed a defect in the urine concentrating function, which was corrected by vasopressin. Plasma antidiuretic hormone (ADH) was not increased by smoking. His condition was well controlled by deamino-D-arginine vasopressin. However, since February 1992 he has become completely free from the need for medication to control his urine volume. Re-evaluation studies with water deprivation and smoking revealed dramatic improvements in the urine concentrating function and ADH response. A patient with idiopathic diabetes insipidus with spontaneous remission after 8 years is reported.
Nagae
A
A
Second Department of Internal Medicine, Ehime University School of Medicine, Japan.
Kohara
K
K
Iwata
T
T
Okura
T
T
Ohtsuka
T
T
Kukita
H
H
Hiwada
K
K
D003919:Diabetes Insipidus / Q000097:blood / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D014667:Vasopressins / Q000097:blood; D014868:Water Deprivation / Q000502:physiology
D014667:Vasopressins