title: Emergence of leprosy in a patient with mycosis fungoides.
abstract: A patient with mycosis fungoides that had progressed to tumor stage responded to chemotherapy and electron beam treatment, but 6 years later a peripheral neuropathy, extensive plaques, erythroderma, and enlarged pinnae containing acid-fast organisms developed while he was being treated with photopheresis. The skin lesions cleared with administration of rifampin and dapsone, but a reversal reaction biopsy specimen showed features of both mycosis fungoides and leprosy. This case raises the question of whether there may be an association between mycosis fungoides and leprosy.
authors.affiliation: Department of Dermatology, Baylor College of Medicine, Houston, TX 77030.
authors.forename: D
authors.initials: D
authors.lastname: Grossman
authors.forename: R P
authors.initials: RP
authors.lastname: Rapini
authors.forename: B
authors.initials: B
authors.lastname: Osborne
authors.forename: M
authors.initials: M
authors.lastname: Duvic
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003622:Dapsone / Q000627:therapeutic use; D006801:Humans; D015440:Leprosy, Lepromatous / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D017893:Photopheresis; D012293:Rifampin / Q000627:therapeutic use; D017192:Skin Diseases, Bacterial / Q000150:complications* / Q000188:drug therapy; D012878:Skin Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy
chemical_list: D003622:Dapsone; D012293:Rifampin