title: Classification of hypertensive cardiomyopathy.
abstract: A clinical pathophysiological classification of hypertensive cardiomyopathy has been established on the basis of the degree to which the heart is affected by chronic, systemic arterial hypertension: Degree I: Asymptomatic patients without left ventricular hypertrophy but with left ventricular diastolic dysfunction according to Doppler mitral inversion relation (E/A < 0.9) or to gamma scintigraphy (peak filling rate reduction < or = 2.7 EDC.s-1. These patients are classified as Group 1. Degree II: Asymptomatic or mildly symptomatic patients (New York Heart Association class I) with echocardiographic left ventricular hypertrophy; classified as Group IIA or IIB according to whether weight-adjusted maximal oxygen uptake is normal or below normal, respectively. Degree III: The basic characteristic is the presence of congestive heart failure with normal ejection fraction (EF > or = 50%). Two subsets can be distinguished on the basis of degree of hypertrophy: Group IIIA, with a mass/volume index > 1.8, and IIIB with a mass/volume index < 1.8. The differences between the two are as follows: patients classified as IIIA had a lower rate of regional ischaemia, a higher ejection fraction, a more frequently audible fourth sound, rarely a third sound and a cardiothoracic ratio < 0.5; IIIB patients had a higher prevalence of regional ischaemia (thallium-positive), a frequently audible third sound and a cardiothoracic ratio > 0.5. Degree IV: This category is characterized by the presence of depressed contractility, which could cause heart failure, by an ejection fraction < 50% and an increase in ventricular volumes. Echocardiography shows increased distance between mitral point E and the septum.
authors.affiliation: University of the Basque Country Institute of Cardiology, Hospital Civil de Basurto, Bilbao (Bizkaia), Spain.
authors.forename: M
authors.initials: M
authors.lastname: Iriarte
authors.forename: N
authors.initials: N
authors.lastname: Murga
authors.forename: D
authors.initials: D
authors.lastname: Sagastagoitia
authors.forename: M
authors.initials: M
authors.lastname: Morillas
authors.forename: J
authors.initials: J
authors.lastname: Boveda
authors.forename: E
authors.initials: E
authors.lastname: Molinero
authors.forename: J
authors.initials: J
authors.lastname: Etxebeste
authors.forename: A
authors.initials: A
authors.lastname: Salcedo
authors.forename: E
authors.initials: E
authors.lastname: Rodriguez
authors.forename: J M
authors.initials: JM
authors.lastname: Ormaetxe
mesh_terms: D000328:Adult; D006332:Cardiomegaly / Q000145:classification* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D016277:Ventricular Function, Left