title: Nasopharyngeal carcinoma: a 15-year retrospective study.
abstract: Malignancy in the nasopharynx, although uncommon, is potentially devastating because of the anatomy of the region and benign early symptoms, which result in infrequent early diagnosis. High-dose radiation therapy, with fields including the oral structures, is the treatment of choice and may result in significant oral complications. This paper reviews 39 cases of nasopharyngeal carcinoma diagnosed at the University of North Carolina Hospitals over a 15-year period. Patient demographics, histopathology, presenting signs and symptoms, stage at diagnosis, possible risk factors, treatment modalities, survival, side-effects of therapy, and dental intervention are reported.
authors.affiliation: Department of Dentistry, Bowman-Gray School of Medicine, Winston-Salem, NC.
authors.forename: K E
authors.initials: KE
authors.lastname: Chapman
authors.forename: L L
authors.initials: LL
authors.lastname: Patton
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D017742:Dental Care for Chronically Ill; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012744:Sex Ratio; D015996:Survival Rate