title: Mortality trend from prostate cancer in The Netherlands (1950-1989).
abstract: The trend in prostate cancer mortality in The Netherlands was studied, using data from the National Causes of Death Registry of the Central Bureau of Statistics. During the period 1950-1989, the age-adjusted mortality rate showed a steady rise from 20.5 to 30.6 per 100,000 man-years. A multiplicative model was used to examine possible period effects and birth-cohort effects separately. This analysis demonstrated that the increase in prostate cancer mortality is largely due to a birth-cohort effect, though calendar time of death may have had a slight effect as well. Among Dutch men, a continuous increase of mortality from prostate cancer was found in consecutive birth cohorts. This finding is in contrast with that of comparable studies in other Western countries, in which a peak mortality rate was found for the cohort born at the end of the 19th century with stabilizing or declining rates for later birth cohorts.
authors.affiliation: Department of Occupational Medicine, University of Nijmegen, The Netherlands.
authors.forename: J W
authors.initials: JW
authors.lastname: van der Gulden
authors.forename: L A
authors.initials: LA
authors.lastname: Kiemeney
authors.forename: A L
authors.initials: AL
authors.lastname: Verbeek
authors.forename: H
authors.initials: H
authors.lastname: Straatman
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D011471:Prostatic Neoplasms / Q000401:mortality*