Changing role of surgery in childhood lymphomas.
The use of combinations of chemo- and radiotherapy have decreased the need for surgical staging of Hodgkin's disease. The goal of decreasing therapy while maintaining cure rates, however, recreates a need for staging. Attempts are being made to devise criteria to decrease the need for surgical staging or to decrease the extent of the procedure. Non-Hodgkin's lymphoma requires adequate tissue samples for analysis, for example, for immunophenotyping to determine treatment. Surgical resection in non-Hodgkin's lymphoma is inadequate for treatment but may be helpful. Debulking, however, is no longer recommended.
Ternberg
J L
JL
Department of Surgery, St. Louis Children's Hospital, Missouri.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D006689:Hodgkin Disease / Q000473:pathology / Q000601:surgery / Q000628:therapy; D006801:Humans; D008223:Lymphoma / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000601:surgery / Q000628:therapy; D009367:Neoplasm Staging