title: [Value of ultrasonography in the early diagnosis of hepatocellular carcinoma].
abstract: The size and the treatment of 135 hepatocellular carcinomas (HCC) has been analyzed, comparing patients diagnosed by a US screening program (group 1) and these diagnosed outside this program (group 2) to determine whether US screening on patients with chronic liver disease is able to diagnose (HCC) at an early stage. alpha-fetoprotein levels above 500 U/ml were considered as diagnostic. Twenty (46.5%) out of 43 patients from group 1 showed a HCC < 5 cm. vs. 14/92 (15.2%) in group 2 (p = 0.001). Only 5.9% of the HCC < 5 cm. showed AFP > 500 U/ml. vs. 29.7% of the advanced HCC (p = 0.003). 88.3% of patients of group 1 vs. 63% of group 2 received specific treatment for HCC (p = 0.002). By means of US screening it is possible to diagnose HCC of smaller size and more susceptible to treatment. AFP is not useful in the early diagnosis of HCC.
authors.affiliation: Sección de Hepatología, Hospital de la Santa Creu i Sant Pau, Barcelona.
authors.forename: F J
authors.initials: FJ
authors.lastname: Martínez Cerezo
authors.forename: M
authors.initials: M
authors.lastname: Puig
authors.forename: A
authors.initials: A
authors.lastname: Martínez Nogueras
authors.forename: A
authors.initials: A
authors.lastname: Tomás
authors.forename: J
authors.initials: J
authors.lastname: Pamplona
authors.forename: C
authors.initials: C
authors.lastname: Guarner
authors.forename: J
authors.initials: J
authors.lastname: Balanzó
authors.forename: J
authors.initials: J
authors.lastname: Enríquez
authors.forename: F
authors.initials: F
authors.lastname: Vilardell
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D013997:Time Factors; D014463:Ultrasonography
vernacular_title: Valor de la ecografía en el diagnóstico precoz del carcinoma hepatocelular.