title: [Tetrazepam in the treatment of acute cervical syndrome. Randomized double-blind pilot study comparing tetrazepam and placebo].
abstract: METHODS
  In a double-blind study, 20 ambulatory patients with acute painful restriction of mobility of the cervical spine and overall marked impairment were treated for seven days with tetrazepam (150 mg or a lower dose from the third day onward) or placebo. Paracetamol was permitted in addition if required. Test criteria: The main criterion of efficacy was a summed score of three parameters: pain, restriction of mobility, and general impairment.
  
  
  RESULTS
  The difference between the groups was statistically highly significant (p = 0.005). Tolerability was adjudged to be "very good" for the placebo group, and, on average, "good" for the tetrazepam group.
authors.affiliation: Sanofi-Winthrop GmbH, Medizinische Abteilung, München.
authors.forename: E
authors.initials: E
authors.lastname: Salzmann
authors.forename: O
authors.initials: O
authors.lastname: Wiedemann
authors.forename: L
authors.initials: L
authors.lastname: Löffler
authors.forename: H
authors.initials: H
authors.lastname: Sperber
mesh_terms: D000328:Adult; D000368:Aged; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000627:therapeutic use*; D002574:Cervical Vertebrae; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D009129:Muscle Tonus / Q000187:drug effects*; D009334:Neck Muscles / Q000293:injuries; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement; D010865:Pilot Projects; D011602:Psychophysiologic Disorders / Q000188:drug therapy; D016059:Range of Motion, Articular / Q000187:drug effects; D013122:Spinal Diseases / Q000188:drug therapy*
chemical_list: D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D009125:Muscle Relaxants, Central; D001569:Benzodiazepines; C005245:tetrazepam
vernacular_title: Tetrazepam in der Behandlung akuter Zervikalsyndrome. Randomisierte doppelblinde Pilotstudie zum Vergleich von Tetrazepam und Plazebo.