Regulation of the Escherichia coli hfq gene encoding the host factor for phage Q beta.
The host factor (HF-I) for phage Q beta RNA replication is a small protein of 102 amino acid residues encoded by the hfq gene at 94.8 min on the Escherichia coli chromosome. The synthesis rate of HF-I at the exponential-growth phase is higher than at the stationary phase, and it increases concomitantly with the increase in cell growth rate. The intracellular level of HF-I is about 30,000 to 60,000 molecules per cell, the majority being associated with ribosomes as one of the salt wash proteins. Taken together, we suggest that HF-I is one of the growth-related proteins.
Kajitani
M
M
Department of Molecular Genetics, National Institute of Genetics, Shizuoka, Japan.
Kato
A
A
Wada
A
A
Inokuchi
Y
Y
Ishihama
A
A
D017908:Allolevivirus / Q000254:growth & development*; D002352:Carrier Proteins / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D002458:Cell Fractionation; D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism; D029968:Escherichia coli Proteins; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial / Q000235:genetics*; D035001:Host Factor 1 Protein; D034982:Integration Host Factors
D002352:Carrier Proteins; D029968:Escherichia coli Proteins; D035001:Host Factor 1 Protein; D034982:Integration Host Factors; C440502:integration host factor, E coli