title: Antioxidant systems and erythrocyte life-span in mammals.
abstract: 1. Erythrocyte antioxidant systems--superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), glutathione peroxidase (GSH-Px), glutathione S-transferase (GST) and glutathione reductase (GR)--were discussed in relation to life-spans in some mammalian species. 2. The erythrocyte life-span of different mammals was found to be correlated with the levels of SOD, GSH-Px and GSH. 3. Data reviewed indicates that the erythrocyte life-span of each species is governed by both the oxygen radical formation and the efficiency of intrinsic antioxidant systems.
authors.affiliation: Department of Veterinary Medicine, Faculty of Agriculture, Gifu University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kurata
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: N S
authors.initials: NS
authors.lastname: Agar
mesh_terms: D000818:Animals; D004905:Erythrocyte Aging / Q000502:physiology*; D004912:Erythrocytes / Q000201:enzymology; D008322:Mammals / Q000097:blood*; D010084:Oxidation-Reduction