Synthesis and antifungal activity of novel cationic pneumocandin B(o) derivatives.
Bouffard
F A
FA
Department of Synthetic Chemical Research, Merck Research Laboratories, Rahway, New Jersey 07065.
Zambias
R A
RA
Dropinski
J F
JF
Balkovec
J M
JM
Hammond
M L
ML
Abruzzo
G K
GK
Bartizal
K F
KF
Marrinan
J A
JA
Kurtz
M B
MB
McFadden
D C
DC
D000818:Animals; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000627:therapeutic use; D054714:Echinocandins; D051379:Mice; D008811:Mice, Inbred DBA; D009181:Mycoses / Q000188:drug therapy; D010455:Peptides; D010456:Peptides, Cyclic / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D054714:Echinocandins; D010455:Peptides; D010456:Peptides, Cyclic; C079465:pneumocandin B(0)