Giant cell fibroblastoma with dermatofibrosarcoma protuberans-like transformation.
A giant cell fibroblastoma (GCF) presented in the subcutis of the breast in a 13-month-old girl which recurred 6 years later as a dermal and subcutaneous neoplasm whose patterns were in part GCF and spindle cells with a storiform configuration resembling dermatofibrosarcoma protuberans (DFSP). The issue remains unsettled as to whether GCF is the juvenile variant of DFSP, but an argument about this relationship is supported circumstantially by a case such as ours.
Perry
D A
DA
Department of Pathology and Surgery, Children's Hospital, Omaha, Nebraska.
Schultz
L R
LR
Dehner
L P
LP
D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002648:Child; D018223:Dermatofibrosarcoma / Q000473:pathology*; D005260:Female; D005354:Fibrosarcoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery