C-ANCA and p-ANCA positive vasculitis with crescentic glomerulonephritis: the same clinical feature but different immunological pathways?
Patients with cytoplasmatic (c)-ANCA positive vasculitis and crescentic glomerulonephritis (n = 25) had similar clinical presentation, age, sex distribution, organ involvement, therapy requirements, and outcome as patients with perinuclear (p)-ANCA positive vasculitis and crescentic glomerulonephritis (n = 7). Therefore, we conclude that these two entities are very closely related or even the same disease.
Grotz
W
W
Medizinische Universitätsklinik Freiburg, Germany.
Röther
E
E
Schollmeyer
P
P
D000328:Adult; D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D005921:Glomerulonephritis / Q000150:complications / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009195:Peroxidase / Q000276:immunology; D014657:Vasculitis / Q000150:complications / Q000276:immunology*
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D007074:Immunoglobulin G; D009195:Peroxidase