[Clinical aspects and outcome of recurrent pulmonary tuberculosis].
Recurrent tuberculosis was treated in hospital in 86 patients, 82.7% of whom had destructive disease, while 84.0% disseminated the bacteria. Combined chemotherapy included 4 tuberculostatic drugs: 10% isoniazid (7 mg/kg iv drip), streptomycin (0.5 g intramuscularly), rifadin (0.6 g orally) and tisamid (25-30 mg/kg orally). The drugs were given twice a week under the intermittent regimen in combination with 10% isoniazid (7 mg/kg) and streptomycin (0.5 g) inhalations. During a mean hospital stay of 6.5 months disappearance of destruction and discontinuation of the bacilli dissemination were achieved in 91.1% and 93.9% of patients, respectively, suffering from infiltrative and disseminated tuberculosis.
Krasnov
V A
VA
Potashova
V A
VA
Zyrianova
T V
TV
Naryshkina
S L
SL
D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011718:Pyrazinamide / Q000627:therapeutic use*; D012008:Recurrence; D012293:Rifampin / Q000627:therapeutic use*; D013307:Streptomycin / Q000627:therapeutic use*; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology
D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin
Klinicheskoe techenie i iskhody retsidiva tuberkulëza lëgkikh.