title: The mammalian Na+/H+ exchanger gene family--initial structure/function studies.
abstract: A gene family of mammalian Na+/H+ exchangers has been identified. Three isoforms have been cloned, sequenced, and stably expressed, and structure/function studies have been begun. Several of the isoforms are found in the epithelia, and one of them is epithelial specific.
authors.forename: M
authors.initials: M
authors.lastname: Tse
authors.forename: S
authors.initials: S
authors.lastname: Levine
authors.forename: C
authors.initials: C
authors.lastname: Yun
authors.forename: S
authors.initials: S
authors.lastname: Brant
authors.forename: J
authors.initials: J
authors.lastname: Pouyssegur
authors.forename: M
authors.initials: M
authors.lastname: Donowitz
mesh_terms: D000584:Amiloride / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D006801:Humans; D007082:Ileum / Q000378:metabolism; D015394:Molecular Structure; D005810:Multigene Family; D011817:Rabbits; D051381:Rats; D017923:Sodium-Hydrogen Exchangers / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D017923:Sodium-Hydrogen Exchangers; D000584:Amiloride