[Topical treatment of psoriasis with calcipotriol. Report of clinical experience].
BACKGROUND
Numerous clinical studies have demonstrated the efficacy of calcipotriol, a synthetic vitamin D3 analogue, in the treatment of mild to moderate chronic psoriasis.


METHODS
Report on clinical experience of 40 psoriasis patients treated with calcipotriol, alone or in combination with phototherapy.


RESULTS
After four weeks of treatment, the condition had largely cleared up in eleven out of 18 patients (61%) receiving calcipotriol alone, and in 20 out of 22 patients (91%) receiving combination treatment with UVB or UVA plus UVB. The new anti-psoriasis agent was well tolerated and readily accepted by the patients.


CONCLUSIONS
Calcipotriol represents a valuable addition to the available therapy spectrum in chronic psoriasis.
Hofmann
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C
Schirle
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D000287:Administration, Topical; D002117:Calcitriol / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D004359:Drug Therapy, Combination; D006801:Humans; D011701:PUVA Therapy; D011565:Psoriasis / Q000188:drug therapy*
D003879:Dermatologic Agents; C055085:calcipotriene; D002117:Calcitriol
Topische Behandlung der Psoriasis mit Calcipotriol. Ein klinischer Erfahrungsbericht.