[The immune status in different clinical forms of insulin-dependent diabetes mellitus].
Immune status with reference to the disease duration and genetic factors (HLA-typing) was studied in various clinical variants of insulin-dependent diabetes mellitus. The disease duration appeared the key factor in development of immune deficiency in insulin-dependent diabetes mellitus. Critical immunological values were established (CD5+ cells--1200 in 1 microliter, CD4+ cells--35%, expression of CD5 and antigens HLA class II--110 and 75%, respectively) for septic complications which are highly probable in lower indices. Females with diffuse thyroid enlargement, subclinical hypothyroidism, wide spectrum of antibodies to DNA, antigenic determinants of thyroid gland, hypophysis were found to be a group associated with HLA--DR3 carriage.
Borisova
A M
AM
Efuni
S S
SS
Matiukov
A E
AE
Polianskaia
I S
IS
Shishko
P I
PI
Dreval'
A V
AV
Baliura
A V
AV
Kondrat'ev
Ia Iu
IaIu
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000276:immunology*; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000097:blood; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000276:immunology*; D008297:Male; D012727:Sex Characteristics; D016176:T-Lymphocyte Subsets / Q000276:immunology
D001323:Autoantibodies; D006680:HLA Antigens
Immunnyĭ status pri razlichnykh klinicheskikh formakh insulinzavisimogo sakharnogo diabeta.