title: EMLA-induced analgesia inferior to lignocaine infiltration in curettage of common warts--a randomized study.
abstract: The analgesic effect of topical application of EMLA cream for the curettage verrucae vulgaris was compared to local infiltration with lignocaine in 89 patients. The main purpose of this randomized study was to evaluate the patients' overall impression of the treatment. All patients anaesthetized by lignocaine infiltration reported it as 'an acceptable procedure' compared to only 71% of the patients treated with EMLA. It cannot be recommended to use EMLA cream as local anaesthetic for curettage of verrucae vulgaris, presumably because the highly keratotic nature of the common warts does not allow sufficient penetration of epicutaneously applied EMLA.
authors.affiliation: Private Dermatological Clinics in Lyngby, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Vesterager
authors.forename: K P
authors.initials: KP
authors.lastname: Petersen
authors.forename: R
authors.initials: R
authors.lastname: Nielsen
authors.forename: A M
authors.initials: AM
authors.lastname: Niordson
authors.forename: M
authors.initials: M
authors.lastname: Gammeltoft
authors.forename: C
authors.initials: C
authors.lastname: Graudal
authors.forename: D
authors.initials: D
authors.lastname: Stahl
mesh_terms: D000293:Adolescent; D000328:Adult; D000779:Anesthetics, Local; D002648:Child; D003475:Curettage; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007267:Injections; D008012:Lidocaine / Q000008:administration & dosage*; D000077442:Lidocaine, Prilocaine Drug Combination; D008297:Male; D008875:Middle Aged; D009824:Ointments; D010147:Pain Measurement; D011318:Prilocaine / Q000008:administration & dosage*; D014860:Warts / Q000601:surgery*
chemical_list: D000779:Anesthetics, Local; D004338:Drug Combinations; D000077442:Lidocaine, Prilocaine Drug Combination; D009824:Ointments; D011318:Prilocaine; D008012:Lidocaine