[Effect of pyrazole on the activity of acetaldehyde-producing enzymes in the liver].
Influence of pyrazole on the endogenous ethanol level and activities of acetaldehyde-producing enzymes was investigated. Drastic enhancement of the endogenous ethanol level in the blood and tissues was accompanied by an insignificant increase of phosphoethanolamine lyase activity, while activity of threonine aldolase and pyruvate dehydrogenase was unchanged.
Gerashchenko
D Iu
DIu
Gorenshteĭn
B I
BI
Pyzhik
T N
TN
Ostrovskiĭ
Iu M
IuM
D000079:Acetaldehyde / Q000378:metabolism*; D000410:Alanine Transaminase / Q000187:drug effects; D000818:Animals; D019757:Carbon-Oxygen Lyases; D005969:Glutamate Dehydrogenase / Q000187:drug effects; D012696:Glycine Hydroxymethyltransferase / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D008190:Lyases / Q000187:drug effects; D008297:Male; D011720:Pyrazoles / Q000494:pharmacology*; D011768:Pyruvate Dehydrogenase Complex / Q000187:drug effects; D051381:Rats; D000637:Transaminases / Q000187:drug effects
D011720:Pyrazoles; D011768:Pyruvate Dehydrogenase Complex; C031280:pyrazole; D005969:Glutamate Dehydrogenase; D012696:Glycine Hydroxymethyltransferase; D000637:Transaminases; C019741:asparagine-oxo-acid aminotransferase; D000410:Alanine Transaminase; D008190:Lyases; D019757:Carbon-Oxygen Lyases; C020127:ethanolaminephosphate phospho-lyase; D000079:Acetaldehyde
Vliianie pirazola na aktivnost' atsetal'degidprodutsiruiushchikh fermentov pecheni.