New variant t(9;11;14)(p22;q23;q24) suggests a translocation of 9p to 11q as the critical genetic event.
We describe a patient with M5a (FAB classification) associated with a new type of variant translocation (9;11), namely t(9;11;14)(p22;q23;q24). The translocation of chromosome fragment from 9p to 11q is the common feature among the five variant translocations in the literature and our patient.
Miura
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I
Third Department of Internal Medicine, Akita University School of Medicine, Japan.
Yamaguchi
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A
Takatsu
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H
Miura
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AB
D000368:Aged; D002880:Chromosomes, Human, Pair 11 / Q000648:ultrastructure*; D002883:Chromosomes, Human, Pair 14 / Q000648:ultrastructure*; D002899:Chromosomes, Human, Pair 9 / Q000648:ultrastructure*; D006801:Humans; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic