title: A comparison of narrow band phototherapy (TL-01) and photochemotherapy (PUVA) in the management of polymorphic light eruption.
abstract: Twenty-five patients suffering from severe polymorphic light eruption (PLE) were randomized to either photochemotherapy (PUVA) or narrow-band phototherapy (TL-01 UVB) treatment in early spring; patients receiving UVB were given placebo tablets to achieve a matching therapy procedure. During the 4 months following treatment, patient exposure to solar UVB was monitored with polysulphone badges. PLE occurrence, severity, and restriction of outdoor activity were recorded, using weekly diary-sheets. Analysis of covariance on this data, using the logarithm of UVB exposure as the explanatory variable, showed no significant differences between the treatments. TL-01 UVB is an effective alternative to PUVA in the management of PLE.
authors.affiliation: Department of Photobiology, Ninewells Hospital and Medical School, Dundee, U.K.
authors.forename: D
authors.initials: D
authors.lastname: Bilsland
authors.forename: S A
authors.initials: SA
authors.lastname: George
authors.forename: N K
authors.initials: NK
authors.lastname: Gibbs
authors.forename: T
authors.initials: T
authors.lastname: Aitchison
authors.forename: B E
authors.initials: BE
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Ferguson
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D010787:Photosensitivity Disorders / Q000517:prevention & control*; D012621:Seasons; D014467:Ultraviolet Therapy / Q000295:instrumentation