title: Secondary antibody response to Haemophilus somnus antigen in breeding Japanese black cattle fed selenium-deficient and alpha-tocopherol-fortified diets.
abstract: The cattle with adequate alpha-tocopherol (Vit E) and marginally deficient selenium (Se) status manifested significantly lower anti-Haemophilus somnus antibody titer than the cattle supplemented with Se in the later stage of an 8-week trial. However, in the early stage no difference was observed in magnitude of anti-H. somnus antibody development between them. These results suggested that Se may contribute to anti-H. somnus antibody production, and that Vit E can make up for Se deficiency to a certain degree.
authors.affiliation: Department of Veterinary Internal Medicine, Faculty of Agriculture, Miyazaki University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Makimura
authors.forename: A
authors.initials: A
authors.lastname: Kodama
authors.forename: M
authors.initials: M
authors.lastname: Kishita
authors.forename: H
authors.initials: H
authors.lastname: Takagi
authors.forename: K
authors.initials: K
authors.lastname: Adachi
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D000917:Antibody Formation; D002417:Cattle; D004032:Diet; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D006190:Haemophilus / Q000276:immunology*; D011247:Pregnancy; D012643:Selenium / Q000097:blood / Q000172:deficiency*; D013997:Time Factors; D014810:Vitamin E / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D000907:Antibodies, Bacterial; D014810:Vitamin E; D005979:Glutathione Peroxidase; D012643:Selenium