title: Dauricoside, a new glycosidal alkaloid having an inhibitory activity against blood-platelet aggregation.
abstract: Dauricoside (1), a new glycosidal alkaloid, was isolated from the rhizomes of Menispermum dauricum DC. along with dauricine (2), daurisoline (3), dauriporphine (4), menisporphine (5), and 6-O-demethylmenisporphine (6), and its structure was determined by means of spectroscopic methods. Compounds 1, 2, and 3 inhibited blood-platelet aggregation induced by adenosine 5'-diphosphate (ADP).
authors.affiliation: Shenyang College of Pharmacy, China.
authors.forename: S M
authors.initials: SM
authors.lastname: Hu
authors.forename: S X
authors.initials: SX
authors.lastname: Xu
authors.forename: X S
authors.initials: XS
authors.lastname: Yao
authors.forename: C B
authors.initials: CB
authors.lastname: Cui
authors.forename: Y
authors.initials: Y
authors.lastname: Tezuka
authors.forename: T
authors.initials: T
authors.lastname: Kikuchi
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D011817:Rabbits
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D006027:Glycosides; D010975:Platelet Aggregation Inhibitors; C085280:dauricoside