title: Isolated congenital atrichia in an Omani kindred.
abstract: Congenital atrichia may occur isolated or with associated defects. The isolated variant is especially uncommon. Sporadic and familial cases have been rarely reported. We present a large inbred kindred from Oman where 22 affected members with this disorder were found over six generations. The male-to-female ratio was 1:1.4. No associated ectodermal or other defects were noted. A typical autosomal recessive mode of inheritance was documented. Though inbreeding was high, anticipated quasidominance was observed only once.
authors.affiliation: Department of Human and Clinical Anatomy, College of Medicine, Sultan Qaboos University, Muscat, Sultanate of Oman.
authors.forename: R K
authors.initials: RK
authors.lastname: Kenue
authors.forename: K S
authors.initials: KS
authors.lastname: al-Dhafri
mesh_terms: D000505:Alopecia / Q000151:congenital* / Q000235:genetics* / Q000473:pathology; D002648:Child; D003241:Consanguinity; D004439:Eccrine Glands / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree; D012744:Sex Ratio; D012867:Skin / Q000473:pathology