Antiphospholipid syndrome in pregnancy: a diagnostic dilemma.
OBJECTIVE
To present a case of severe pre-eclampsia in which diagnosis of the antiphospholipid syndrome was made after delivery, and to discuss pointers to the diagnosis.


METHODS
A 32-year-old woman in her second pregnancy presented at 32 weeks' gestation with severe pre-eclampsia. Her persisting severe postpartum illness was investigated. The presence of anticardiolipin antibodies and lupus anticoagulant led to the diagnosis of antiphospholipid syndrome.


RESULTS
Induction of labour was successful, with delivery of a healthy baby girl. The patient made a full recovery after treatment with corticosteroids and warfarin.


CONCLUSIONS
The antiphospholipid syndrome should be considered in cases of severe early pre-eclampsia.
Clark
F L
FL
James Paget Hospital, Great Yarmouth, Norfolk, United Kingdom.
Greenwood
P
P
Forster
P J
PJ
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*