Antioxidant systems and erythrocyte life-span in mammals.
1. Erythrocyte antioxidant systems--superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), glutathione peroxidase (GSH-Px), glutathione S-transferase (GST) and glutathione reductase (GR)--were discussed in relation to life-spans in some mammalian species. 2. The erythrocyte life-span of different mammals was found to be correlated with the levels of SOD, GSH-Px and GSH. 3. Data reviewed indicates that the erythrocyte life-span of each species is governed by both the oxygen radical formation and the efficiency of intrinsic antioxidant systems.
Kurata
M
M
Department of Veterinary Medicine, Faculty of Agriculture, Gifu University, Japan.
Suzuki
M
M
Agar
N S
NS
D000818:Animals; D004905:Erythrocyte Aging / Q000502:physiology*; D004912:Erythrocytes / Q000201:enzymology; D008322:Mammals / Q000097:blood*; D010084:Oxidation-Reduction