title: Immediate results of interventional devices for coronary ostial narrowing with angina pectoris.
abstract: Angioplasty of aorto-ostial lesions has had suboptimal results. This study reports on the immediate results of new debulking devices (atherectomy, excimer laser) in the treatment of aorto-ostial disease. Thirty-one vessels (29 patients) with an ostial lesion treated with a new device (group I) were compared with 15 vessels (13 patients) with an ostial lesion treated with angioplasty alone during the preceding 24 months (group II). Both groups were similar in their clinical characteristics. A larger proportion of vessels in group I (64%) compared with group II (7%) had unfavorable features for angioplasty. Procedural success was similar: 28 vessels in group I (91%) and 14 in group II (93%). Among the new devices, success was also similar: atherectomy in 8 arteries (89%), rotablator in 4 (100%) and excimer laser in 17 (94%). The acute gain was more significant with new devices: absolute reduction in percent stenosis was 66% for directional atherectomy, 67% for rotational atherectomy (p = 0.016 compared with angioplasty), 52% for excimer laser (p = 0.09) and 46% for angioplasty. In group I, 2 patients (6%) required emergency bypass surgery during our early experience; no deaths or Q-wave myocardial infarctions occurred. Group II had no complications. Therefore in aorto-ostial lesions, despite a much higher prevalence of unfavorable angiographic characteristics, new devices had (1) a success rate of > or = 90%, (2) a significantly larger acute gain compared with angioplasty alone, and (3) an acceptable complication rate. Larger studies with complete angiographic follow-up are needed to assess restenosis.
authors.affiliation: Cardiac Catheterization Laboratory, Medical College of Virginia, Richmond.
authors.forename: M N
authors.initials: MN
authors.lastname: Sabri
authors.forename: M J
authors.initials: MJ
authors.lastname: Cowley
authors.forename: G
authors.initials: G
authors.lastname: DiSciascio
authors.forename: D
authors.initials: D
authors.lastname: DeBottis
authors.forename: K
authors.initials: K
authors.lastname: Kelly
authors.forename: E
authors.initials: E
authors.lastname: Goudreau
authors.forename: G W
authors.initials: GW
authors.lastname: Vetrovec
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D000787:Angina Pectoris / Q000209:etiology / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D017225:Atherectomy, Coronary / Q000379:methods; D003327:Coronary Disease / Q000150:complications / Q000628:therapy*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome