title: AB5046A and B, novel chlorosis-inducing substances from Nodulisporium sp.
abstract: Novel chlorosis-inducing substances, AB5046A and B, were isolated from the culture broth of a fungal strain. The producing organism, designated AB5046, was identified as a member of Nodulisporium. AB5046A and B were purified by extraction with EtOAc and silica gel chromatography. The structure of AB5046A and B were determined to be 2-butyryl-3,5-dihydroxy-cyclohex-2-ene-1-one and 2-acetyl-3,5-dihydroxy-cyclohex-2-ene-1-one, respectively, by spectroscopic analyses. AB5046A and B induced chlorosis against Japanese barnyard millet in vitro. The chlorosis activity of these compounds was stronger against monocotyledons than dicotyledons.
authors.affiliation: Central Research Laboratories, Hokko Chemical Industries Co. Ltd., Kanagawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Igarashi
authors.forename: Y
authors.initials: Y
authors.lastname: Tetsuka
authors.forename: Y
authors.initials: Y
authors.lastname: Mimura
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Tamamura
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Naganawa
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003512:Cyclohexanones / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity*; D005658:Fungi / Q000737:chemistry* / Q000378:metabolism; D006540:Herbicides / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008897:Panicum / Q000187:drug effects; D010935:Plant Diseases / Q000139:chemically induced*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D003512:Cyclohexanones; D006540:Herbicides; C085618:AB 5046A; C085619:AB 5046B