title: Eosinophilic granuloma of the hand.
abstract: The first reported case of eosinophilic granuloma of the hand is presented. A slowly expanding lesion of the right third metacarpal shaft was treated by biopsy and curettage. Histological examination confirmed the presence of eosinophilic granuloma. A bone scan showed that it was a solitary lesion. There has been no evidence of recurrence of the lesion during follow-up. Eosinophilic granuloma is a rare disease of the mononuclear phagocyte system, representing one of the clinical manifestations of Langerhans-cell histiocytosis. The lesions are usually associated with the skull, femur, mandible and ribs; this condition has not been previously reported in the hand.
authors.affiliation: Department of Orthopaedic Surgery, Northwick Park Hospital, London, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Miller
authors.forename: W W
authors.initials: WW
authors.lastname: Williams
mesh_terms: D000328:Adult; D004803:Eosinophilic Granuloma / Q000473:pathology / Q000601:surgery*; D006225:Hand; D006801:Humans; D008297:Male; D008663:Metacarpus