Systolic and diastolic function in tricuspid valve atresia before the Fontan operation.
Systolic and diastolic function were assessed at preoperative cardiac catheterization in 6 patients with classic tricuspid atresia and were compared with those in control subjects. All patients had systemic-to-pulmonary shunts. Left ventricular end-systolic and end-diastolic volumes and masses were significantly larger in the patient group; stroke volume and the ratio of volume to mass were also higher, but not significantly. Mean end-diastolic, peak systolic and end-systolic pressures were similar. Mean stress at end-systole and peak systole were significantly higher in the patient group. Operant chamber stiffness tended to be lower than normal, but was not statistically significant, and myocardial stiffness was normal for the patient group also. Indexes of systolic function were compared. The rate-corrected mean velocity of fiber shortening in the patient group was lower and its relation with stress at end-systole was variable with 4 abnormal patients. The ratio of stress at end-systole/end-systolic volume was significantly lower in patients. The duration of hospital stay did not correlate with end-diastolic volume or any parameter. Thus, this study found abnormalities of load-dependent and independent indexes of systolic function with normal diastolic function in young preoperative patients with tricuspid atresia.
Sandor
G G
GG
Department of Paediatrics and Cardiovascular Surgery, University of British Columbia, British Columbia's Children's Hospital, Vancouver, Canada.
Patterson
M W
MW
LeBlanc
J G
JG
D006328:Cardiac Catheterization; D006348:Cardiac Surgical Procedures / Q000379:methods; D002648:Child; D002675:Child, Preschool; D003971:Diastole / Q000502:physiology*; D006801:Humans; D009200:Myocardial Contraction / Q000502:physiology; D013599:Systole / Q000502:physiology*; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000002:abnormalities* / Q000601:surgery*