[Fenofibrate photoallergy].
Photosensitization to lipid-lowering fibric acid derivatives are rare. We report a case of photoallergy induced by fenofibrate, proved by a positive UVA photo-patch-test. Evolution towards persistent photosensitization is probable, since photobiological abnormalities persisted during four months after fenofibrate was discontinued. The fact that patch-tests to various benzophenones were negative is not in favour of the benzophenone group being responsible for the photosensitization reaction.
Jeanmougin
M
M
Unité de Photodermatologie, Hôpital Saint-Louis, Paris.
Manciet
J R
JR
De Prost
Y
Y
Reygagne
P
P
Pinquier
L
L
Dubertret
L
L
D017454:Dermatitis, Photoallergic / Q000276:immunology / Q000473:pathology*; D004485:Eczema / Q000139:chemically induced* / Q000276:immunology / Q000473:pathology; D011345:Fenofibrate / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010787:Photosensitivity Disorders; D014466:Ultraviolet Rays / Q000009:adverse effects
D011345:Fenofibrate
Photo-allergie au fénofibrate.