[Study of the interaction of DNA with manganese ions by IR-spectroscopy].
DNA complexed with Mn2+ ions in films is studied at different relative humidities and ion contents ([Mn2+]/[P] = 0.4-1) by IR spectroscopy. It is shown that substantially more sorbed water molecules are necessary for the transition of DNA complexed with Mn2+ ions into the double helical conformation (preferentially B-form) that for macromolecules in the absence of ions. DNA-Mn2+ complexes ([Mn2+]/[P] = 1) are able to absorb more water molecules than DNA. The results of the work evidence Mn2+ ion interaction with phosphates and nitrogen bases of the macromolecule: N7G, O6G.
Kornilova
S A
SA
Kapinos
L E
LE
Blagoĭ
Iu P
IuP
D000818:Animals; D002417:Cattle; D004247:DNA / Q000737:chemistry*; D008345:Manganese / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D013055:Spectrophotometry, Infrared
D008345:Manganese; D004247:DNA
Izuchenie vzaimodeĭstviia DNK s ionami margantsa metodom IK-spektroskopii.