[The combined treatment of patients with locally disseminated prostatic cancer].
A randomized study has been made to compare combined treatments of 111 patients with local prostatic cancer (T2b-4N0-2M0). The control also included 33 matched patients previously given estrogen therapy alone. Four treatment regimens were compared: radiation treatment alone (I), combined radiation, drug and estrogen treatments (II), estrogen therapy alone (III), combined estrogens and radiation (IV). The resultant responses were assessed by treatment efficacy, 3-year survival and recurrence-free interval. Regimens II and IV appeared superior to treatment I, scheme II was more effective than III. A three-year recurrence-free interval lasted 72.6%, 55.3% and 40% for combinations II, IV, treatments I and III, respectively.
Matveev
B P
BP
Iiazaliev
K T
KT
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology / Q000628:therapy; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D011879:Radiotherapy Dosage; D012074:Remission Induction
Kombinirovannoe lechenie bol'nykh mestnorasprostranennym rakom predstatel'noĭ zhelezy.