Early diagnosis of typhoid fever using monoclonal antibody.
In our study, a reverse passive hemagglutination assay (RPHA) method was established using monoclonal antibody-IgM to detect the Salmonella typhi O9 antigen. This method has the advantages of sensitivity, specificity, rapidity, and simplicity, and helps make an early diagnosis of typhoid fever using only small amounts of blood.
Xi
W
W
Wu Jin People's Hospital, Jiangsu.
Ni
X
X
Lu
T
T
Zhang
J
J
Xu
J
J
Huang
M
M
Wu
C
C
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis*; D000942:Antigens, Bacterial / Q000276:immunology; D006386:Hemagglutination Tests / Q000379:methods; D006801:Humans; D006825:Hybridomas / Q000378:metabolism; D051379:Mice; D012485:Salmonella typhi / Q000276:immunology*; D012680:Sensitivity and Specificity; D014435:Typhoid Fever / Q000175:diagnosis*
D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial