title: Epidemiology of salmonellosis and its sensitivity in Karachi.
abstract: Over the past five years 25,000 blood cultures were screened for septicaemia. Of these 6.7% were positive for salmonella species, the commonest being salmonella typhi accounting for 92% of total salmonella isolates. Over the years, S. typhi showed a gradual decline ranging from 96.7 to 87%. While salmonella paratyphi A has shown a gradual increase ranging from 2.5% to 11.4%. Salmonellosis peaked in the year 1990 suggesting an epidemic. The antibiotic sensitivity pattern showed a gradual increase in resistance over the years and even resistance to the new quinolones has emerged. Thus salmonellosis poses a major threat to the community and we must look into the alternative antibiotics to combat the threat.
authors.affiliation: Zafar Research and Diagnostic Centre, Karachi.
authors.forename: S
authors.initials: S
authors.lastname: Hafiz
authors.forename: S W
authors.initials: SW
authors.lastname: Khan
authors.forename: R
authors.initials: R
authors.lastname: Shariff
authors.forename: I
authors.initials: I
authors.lastname: Yazdani
authors.forename: Y
authors.initials: Y
authors.lastname: Syed
authors.forename: T
authors.initials: T
authors.lastname: Hafiz
mesh_terms: D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006801:Humans; D010154:Pakistan / Q000453:epidemiology; D012480:Salmonella Infections / Q000453:epidemiology*; D012482:Salmonella paratyphi A; D012484:Salmonella paratyphi B; D012485:Salmonella typhi