24-hour energy expenditure and substrate oxidation rates are unaffected by body fat distribution in obese women.
Twenty-four-hour energy expenditure (EE) and nonprotein respiratory quotient (RQnp) were measured by indirect calorimetry in 19 upper-body-obese (UBO) and 15 lower-body-obese (LBO) women with similar body mass index (BMI) and body fat percent. The measurements were performed in a respiration chamber on a predetermined physical activity program and a controlled diet. No differences between the UBO and LBO groups were found in 24-hour, daytime, and sleeping EE after adjustment for differences in fat-free mass (FFM). Furthermore, no group effect was observed in RQnp, but a positive correlation was found between RQnp and age. Despite the fact that an increased free fatty acid (FFA) turnover has been found in UBO subjects, the present study does not support the contention that upper-body obesity is accompanied by an increased lipid oxidation.
Buemann
B
B
Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
Astrup
A
A
Quaade
F
F
Madsen
J
J
D000273:Adipose Tissue / Q000378:metabolism* / Q000502:physiology; D000328:Adult; D001824:Body Constitution / Q000502:physiology; D015992:Body Mass Index; D001833:Body Temperature Regulation / Q000502:physiology; D002151:Calorimetry; D002940:Circadian Rhythm / Q000502:physiology*; D004734:Energy Metabolism / Q000502:physiology*; D005230:Fatty Acids, Nonesterified / Q000097:blood / Q000378:metabolism; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D009765:Obesity / Q000378:metabolism* / Q000503:physiopathology*; D010084:Oxidation-Reduction; D013997:Time Factors
D005230:Fatty Acids, Nonesterified