title: Headache, thrombolytic therapy, and chronic subdural hemorrhage--a case report.
abstract: Subdural hematomas are well known but infrequent complications of thrombolytic therapy. Although these are usually associated with head trauma, the authors describe a case of a patient who received a particularly aggressive thrombolytic regimen and presented six months later with complaints of nothing more than a headache resistant to medical therapy, without associated neurologic manifestations, which was finally diagnosed as a chronic subdural hematoma by computerized tomography. In the era of thrombolysis, physicians should maintain a heightened index of suspicion for subdural hematoma in patients complaining of headache.
authors.affiliation: Division of Cardiology, Long Island College Hospital, Brooklyn, New York.
authors.forename: P E
authors.initials: PE
authors.lastname: Nathan
authors.forename: D
authors.initials: D
authors.lastname: Sonenblick
authors.forename: V
authors.initials: V
authors.lastname: Chakote
authors.forename: R
authors.initials: R
authors.lastname: Wolf
authors.forename: T J
authors.initials: TJ
authors.lastname: Sacchi
mesh_terms: D000368:Aged; D005260:Female; D006261:Headache / Q000139:chemically induced*; D006408:Hematoma, Subdural / Q000139:chemically induced*; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy; D011994:Recombinant Proteins / Q000009:adverse effects; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D010959:Tissue Plasminogen Activator / Q000009:adverse effects
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator