Suxamethonium-induced muscle pains are not related to cholinesterase activity.
We have investigated the possibility of using the pre-operative measurement of cholinesterase activity to predict the postoperative development of myalgia following the administration of suxamethonium. Seventy-seven patients presenting for elective extraction of wisdom teeth were entered in the study. All patients received a standard anaesthetic regimen, including suxamethonium to facilitate tracheal intubation, and standardised postoperative analgesia. Myalgia was assessed postoperatively and no correlation between muscle pains and cholinesterase activity was found.
Ansermino
J M
JM
Nuffield Department of Anaesthetics, Oxford.
Burke
M A
MA
Upton
P M
PM
McVittie
J
J
Blogg
C E
CE
D000328:Adult; D002802:Cholinesterases / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008964:Molar, Third; D009135:Muscular Diseases / Q000097:blood / Q000139:chemically induced*; D010149:Postoperative Pain / Q000097:blood / Q000139:chemically induced*; D013390:Succinylcholine / Q000009:adverse effects*; D014081:Tooth Extraction
D002802:Cholinesterases; D013390:Succinylcholine