Cellular immune mechanisms in rheumatoid arthritis and other inflammatory arthritides.
Advances in molecular genetics, cellular immunology and microbiology have offered promise in unravelling the aetiopathogenesis of inflammatory arthritides such as rheumatoid arthritis and reactive arthritis. Such insights are challenging the orthodox view that these diseases are primarily autoimmune in nature, and should lead to exciting and novel therapeutic approaches.
Lanchbury
J S
JS
Division of Medicine, UMDS, Guy's Hospital, London, UK.
Pitzalis
C
C
D000818:Animals; D001168:Arthritis / Q000276:immunology* / Q000382:microbiology; D016918:Arthritis, Reactive / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007111:Immunity, Cellular; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D006680:HLA Antigens; D011948:Receptors, Antigen, T-Cell