title: A novel chromosomal abnormality detected in a case of acute myelomonocytic leukemia.
abstract: A not yet recorded translocation, t(3:17)(q21;q23), detected in a case of acute myelomonocytic leukemia, is reported. In spite of an aggressive cytotoxic chemotherapy, the disease showed a rapid fatal course, confirming the dismal prognostic significance of structural, 'primary' chromosomal abnormalities in acute leukemias.
authors.affiliation: Department of Pediatrics, University Federico II, Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Fiorillo
authors.forename: L
authors.initials: L
authors.lastname: Sebastio
authors.forename: L
authors.initials: L
authors.lastname: Del Vecchio
authors.forename: R
authors.initials: R
authors.lastname: Migliorati
authors.forename: C
authors.initials: C
authors.lastname: De Chiara
authors.forename: R
authors.initials: R
authors.lastname: D'Amore
authors.forename: L
authors.initials: L
authors.lastname: Vicari
authors.forename: A
authors.initials: A
authors.lastname: Pastore
authors.forename: C
authors.initials: C
authors.lastname: Selleri
mesh_terms: D002886:Chromosomes, Human, Pair 17; D002893:Chromosomes, Human, Pair 3; D006801:Humans; D007223:Infant; D015479:Leukemia, Myelomonocytic, Acute / Q000235:genetics*; D008297:Male; D011379:Prognosis; D014178:Translocation, Genetic