Acyclovir: is it an effective virostatic agent for orofacial infections?
Oral and intravenous acyclovir formulations provide effective virostasis against many herpes viruses infections, especially severe herpes simplex or varicella-zoster infections in ambulatory and immunocompromised patients. The therapeutic virostatic efficacy of topical acyclovir formulations requires further development, however, especially for orolabial herpetic infections.
Lavelle
C L
CL
University of Manitoba, Department of Oral Biology, Winnipeg, Canada.
D000212:Acyclovir / Q000627:therapeutic use*; D000287:Administration, Topical; D006560:Herpes Labialis / Q000188:drug therapy*; D006562:Herpes Zoster / Q000188:drug therapy; D006801:Humans; D016867:Immunocompromised Host; D013283:Stomatitis, Herpetic / Q000188:drug therapy*
D000212:Acyclovir