title: Small cell carcinoma of the esophagus with an esophago-mediastinal fistula successfully treated by chemoradiation therapy and intubation: a case report.
abstract: A case of esophageal small cell carcinoma with cervical node metastases and an esophago-mediastinal fistula was treated successfully by chemoradiotherapy. The fistula, after irradiation, was handled successfully by esophageal intubation, followed by infusional 5-fluorouracil and cisplatinum chemotherapy, resulting in the closure of the fistula. Two courses of concurrent chemoradiotherapy, followed by additional cisplatinum and etoposide chemotherapy, were administered. The tumor, including the cervical lymph node metastases, disappeared completely after the treatment.
authors.affiliation: Department of Internal Medicine, National Cancer Center Hospital East, Kashiwa.
authors.forename: A
authors.initials: A
authors.lastname: Ohtsu
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
authors.forename: N
authors.initials: N
authors.lastname: Boku
authors.forename: T
authors.initials: T
authors.lastname: Fujii
authors.forename: Y
authors.initials: Y
authors.lastname: Oda
authors.forename: Y
authors.initials: Y
authors.lastname: Miyata
authors.forename: I
authors.initials: I
authors.lastname: Koba
authors.forename: K
authors.initials: K
authors.lastname: Muro
authors.forename: O
authors.initials: O
authors.lastname: Ohnaka
authors.forename: W
authors.initials: W
authors.lastname: Shimizu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000532:radiotherapy* / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004937:Esophageal Fistula / Q000532:radiotherapy* / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D005047:Etoposide / Q000008:administration & dosage; D005402:Fistula / Q000532:radiotherapy* / Q000628:therapy*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007440:Intubation / Q000379:methods; D008207:Lymphatic Metastasis; D008297:Male; D008477:Mediastinal Diseases / Q000532:radiotherapy* / Q000628:therapy*; D008875:Middle Aged; D011879:Radiotherapy Dosage
chemical_list: D003037:Cobalt Radioisotopes; D005047:Etoposide; D002945:Cisplatin; D005472:Fluorouracil