When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs.
Corbett
A H
AH
Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146.
Osheroff
N
N
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D003603:Cytotoxins / Q000378:metabolism*; D004250:DNA Topoisomerases, Type II / Q000378:metabolism*; D006801:Humans
D000970:Antineoplastic Agents; D003603:Cytotoxins; D004250:DNA Topoisomerases, Type II