Nondepolarizing relaxants: new concepts and new drugs.
Less than a decade ago, the only nondepolarizing neuromuscular blocking drugs available to the anesthetist were traditional long-acting drugs such as pancuronium and d-tubocurarine. The revolution that began 10 years ago in our use of relaxants promises to continue unabated into the next decade. Changes in our clinical use of these drugs will be sparked not just by the introduction of new drugs but also by a greater understanding of the pharmacokinetic/pharmacodynamic principles that govern onset and recovery.
Kopman
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Department of Anesthesiology, St. Vincent's Hospital and Medical Center of New York, NY 10011.
D000732:Androstanols; D006801:Humans; D007546:Isoquinolines; D000077590:Mivacurium; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium
D000732:Androstanols; D007546:Isoquinolines; D003473:Neuromuscular Nondepolarizing Agents; D000077590:Mivacurium; D000077123:Rocuronium