Current nonsteroidal anti-inflammatory drug applications for rheumatic diseases.
This article reviews recent knowledge of the pharmacology of non-steroidal anti-inflammatory drugs (NSAIDs). Changes in use and perception of safety considerations are discussed. Additionally, the concept that all NSAIDs are both anti-inflammatory and analgesic is introduced, discussing the mechanism for each effect. A glimpse into the future of NSAIDs is presented, including different formulations and the concept of enantiomers and their possible role in future developments.
Kantor
T G
TG
Department of Medicine, New York University School of Medicine, New York.
D000368:Aged; D000375:Aging / Q000378:metabolism; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy / Q000378:metabolism; D012216:Rheumatic Diseases / Q000188:drug therapy* / Q000378:metabolism
D000894:Anti-Inflammatory Agents, Non-Steroidal