title: [Tracheobronchopathia osteochondroplastica. Personal observation and review of the literature].
abstract: Tracheobronchobathia osteoplastica (TBO) is a benign disease first described in 1855 and rather rare since only 371 cases have been reported so far. The disease is characterized by the presence of subepithelial osteocartilaginous focal lesions without any relation to tracheal rings. The mechanism of its occurrence remains controverted. We report a case of TBO which is particular in that is was associated with atrophic rhinitis, polydactylia and disorder of oesophageal motricity. From a compilation of 113 cases published by French and Anglo-Saxon authors since 1970, it appears that the clinico-radiological and laboratory picture is of little help in the positive diagnosis which in fact rests on three key-points: bronchial endoscopy, pathological examination of bronchial biopsy fragments and thoracic imaging techniques including computerized topography and magnetic resonance imaging. The usually benign course of the disease can be marked by severe complications, such as infections, haemorrhages, acute dyspnoea by extension to the larynx or significant narrowing of the tracheal lumen which may need tracheotomy or surgical resection of the lesions.
authors.affiliation: Centre Laser, Service du Dr J. F. Dumon, Hôpital Sainte-Marguerite, Marseille, France.
authors.forename: A
authors.initials: A
authors.lastname: Mathlouthi
authors.forename: C
authors.initials: C
authors.lastname: Ben Rehouma
authors.forename: S
authors.initials: S
authors.lastname: Ben M'Rad
authors.forename: J F
authors.initials: JF
authors.lastname: Dumon
authors.forename: N
authors.initials: N
authors.lastname: Labbene
authors.forename: B
authors.initials: B
authors.lastname: Driss
authors.forename: M
authors.initials: M
authors.lastname: Sellami
authors.forename: F
authors.initials: F
authors.lastname: Djenayah
mesh_terms: D000328:Adult; D001982:Bronchial Diseases / Q000175:diagnosis* / Q000209:etiology; D001995:Bronchography; D001999:Bronchoscopy; D005260:Female; D006801:Humans; D010009:Osteochondrodysplasias / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014133:Tracheal Diseases / Q000175:diagnosis* / Q000209:etiology
vernacular_title: La trachéobronchopathie chondro-ostéoplastique. Mise au point à propos d'une observation personnelle et d'une revue bibliographique.