Comparison of immunoaffinity chromatography combined with gas chromatography-negative ion chemical ionisation mass spectrometry and radioimmunoassay for screening dexamethasone in equine urine.
A comparison of the sensitive analytical methods of radioimmunoassay (RIA) and immunoaffinity chromatography (IAC) combined with gas chromatography-negative ion chemical ionisation mass spectrometry for the specific and reliable screening of dexamethasone in equine post-race urine is presented. Results from analyses of samples collected from a mare during 144 hours post administration of 26 mg of dexamethasone sodium phosphate are described.
Stanley
S M
SM
Laboratory of the Jockey Club of South Africa, Johannesburg.
Wilhelmi
B S
BS
Rodgers
J P
JP
D000818:Animals; D002846:Chromatography, Affinity / Q000379:methods*; D003907:Dexamethasone / Q000652:urine*; D004300:Doping in Sports; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006736:Horses / Q000652:urine*; D010084:Oxidation-Reduction; D011863:Radioimmunoassay
D003907:Dexamethasone