Lissencephaly syndromes: clinical aspects.
We report clinical and neurophysiological findings in six children (three female, three male) with type I lissencephaly and three children (all female) with type II lissencephaly (Walker-Warburg syndrome). In type I lissencephaly the diagnosis is based only on electroencephalographic (EEG) signs, whereas in type II lissencephaly the diagnosis rests on clinical signs. In type I lissencephaly the EEG typically shows high alpha-beta activity, which is not seen in type II lissencephaly.
Kurlemann
G
G
Kinderklinik (Neuropädiatrie) Westfälische Wilhelms-Universität, Münster, Germany.
Schuierer
G
G
Kuchelmeister
K
K
Kleine
M
M
Weglage
J
J
Palm
D G
DG
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D001706:Biopsy; D002540:Cerebral Cortex / Q000002:abnormalities*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004576:Electromyography; D005124:Eye Abnormalities; D005190:Family; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008831:Microcephaly; D009132:Muscles / Q000000981:diagnostic imaging / Q000473:pathology; D012640:Seizures / Q000209:etiology; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography