title: Experimental studies of laser myocardial revascularization in rats.
abstract: Myocardial revascularization by Nd: YAG laser used in rats with myocardial infarction was studied. The left coronary artery was ligated and the laser channels with a diameter of 300 microns were made immediately by 2.5-4.2 W lasersonics YAG unit. After 24 hours, the rats were killed. Evaluation included hemodynamics, lactate dehydrogenase of myocardium and myocardial infarct size. The results showed that laser myocardial revascularization reduced myocardial infarct size and enzyme leakage, and improved left ventricular function. The study may provide theoretical basis for the clinical applications of this new technique in the treatment of ischemic heart disease.
authors.affiliation: Department of Cardiology, Third Hospital, Beijing Medical University.
authors.forename: J X
authors.initials: JX
authors.lastname: Guo
authors.forename: J
authors.initials: J
authors.lastname: Pan
authors.forename: L
authors.initials: L
authors.lastname: Ma
authors.forename: M Z
authors.initials: MZ
authors.lastname: Chen
authors.forename: H
authors.initials: H
authors.lastname: Xu
authors.forename: A Y
authors.initials: AY
authors.lastname: Shi
mesh_terms: D000818:Animals; D006439:Hemodynamics; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D053685:Laser Therapy; D008297:Male; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D009204:Myocardial Revascularization / Q000379:methods*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D007770:L-Lactate Dehydrogenase