[Regulation of lipid metabolism in blood of weaving shop workers (noise level of about 90 dB A) by alpha-tocopherol acetate].
alpha-Tocopherol acetate, used for repeated treatment within a year of weavers working under highly uncomfortable conditions (the level of noise up to 90 dB), was shown to exhibit the regulating effect on the rate of lipid peroxidation and on content of alpha-tocopherol and cholesterol in blood plasma and erythrocyte membranes as well as on the ratios alpha-tocopherol acetate/total lipids, alpha-tocopherol acetate/cholesterol in blood plasma and cholesterol/alpha-tocopherol acetate in erythrocyte membranes. The vitamin decreased distinctly the atherogenicity coefficient; these data suggest that treatment with tocopherol is essential for prophylaxis of noise-produced impairments.
Melkonian
M M
MM
D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000494:pharmacology*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008055:Lipids / Q000097:blood*; D008875:Middle Aged; D009623:Noise, Occupational; D013783:Textile Industry; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000494:pharmacology; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
D000975:Antioxidants; D008055:Lipids; D014810:Vitamin E; D024502:alpha-Tocopherol; D024505:Tocopherols
Reguliatsiia metabolizma lipidov krovi rabotnits tkatskogo tsekha (uroven' shuma 90 dB A) alpha-tokoferol atsetatom.