Thermolability of residual methylene-tetrahydrofolate reductase (MR) activity, methionine synthase activity and methyl-cobalamin levels in cultured fibroblasts from patients with MR deficiency.
Rosenblatt
D S
DS
Centre for Human Genetics, Hess B. and Diane Finestone Laboratory, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Lue-Shing
H
H
Matiaszuk
N
N
Low-Nang
L
L
Arzoumanian
A
A
Cooper
B A
BA
D002460:Cell Line; D002478:Cells, Cultured; D004795:Enzyme Stability; D005260:Female; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000172:deficiency* / Q000378:metabolism*; D012867:Skin / Q000201:enzymology*; D014805:Vitamin B 12 / Q000031:analogs & derivatives* / Q000378:metabolism
C019476:mecobalamin; D000587:Oxidoreductases Acting on CH-NH Group Donors; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D014805:Vitamin B 12