[Cytokine treatment of renal cell carcinoma].
Cytokine treatment of renal cell carcinoma is described, focusing on interferons (IFN) and interleukin-2 (IL-2). Some cases with excellent responses are being reported, but long term follow-up results are rare. The results of monotherapy by cytokine are not satisfactory, so effective combination therapies with cytokines are awaited in future studies. Effects of the ongoing mono-therapy by cytokines are limited. For further development of the treatment, analyses of the complicated production system of cytokines and interactions are prerequisite.
Tazaki
H
H
Dept. of Urology, School of Medicine, Keio University, Tokyo, Japan.
D002292:Carcinoma, Renal Cell / Q000628:therapy*; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D007376:Interleukin-2 / Q000627:therapeutic use*; D007680:Kidney Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000627:therapeutic use
D016898:Interferon-alpha; D007376:Interleukin-2; D010844:Picibanil