Fetal type II lissencephaly: a case report.
Type II lissencephaly is a rare cortical malformation associated with a number of clinical syndromes, including Walker-Warburg syndrome and some forms of congenital muscular dystrophy. The neuropathology of a 20-week fetus is described showing the pathogenesis of the malformation, which appears to result from abnormal migration of neurons through the pial-glial barrier into the leptomeninges.
Squier
M V
MV
Department of Neuropathology, Radcliffe Infirmary, Oxford, UK.
D001933:Brain Stem / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000002:abnormalities* / Q000473:pathology*; D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D006801:Humans; D008297:Male; D011247:Pregnancy; D013577:Syndrome