[Prevention and antibiotic treatment of Pseudomonas aeruginosa septicemia].
Thirty-six cases of pseudomonas aeruginosa septicemia were found in 5 years from 1986 to 1990. The main risk factors predisposing septicemia included severe underlying diseases and local primary infection or impaired anatomic barrier. The use of broad-spectrum antibiotics, cytotoxic or immunosuppressive therapy, and leukopenia were also important risk factors. The percentages of in vitro resistant strains to 8 antipseudomonal antibiotics varied from 18% to 47%. The overall effective rate was 42% in 26 patients receiving appropriate antibiotic therapy. The mortality attributable to pseudomonas aeruginosa septicemia was 61%. The prevention and antibiotic treatment of pseudomonas aeruginosa septicemia are discussed.
Deng
G H
GH
Peking Union Medical College Hospital, Beijing.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000668:Ampicillin Resistance; D016470:Bacteremia / Q000188:drug therapy* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010878:Piperacillin / Q000494:pharmacology / Q000627:therapeutic use*; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000517:prevention & control; D011550:Pseudomonas aeruginosa / Q000187:drug effects
D010878:Piperacillin