Prevalence of riboflavin deficiency among Guatemalan elderly people and its relationship to milk intake.
Six groups of elderly subjects from central Guatemala were assessed for riboflavin status by using the erythrocyte glutathione reductase activity coefficient (EGRAC). The prevalence of riboflavin deficiency ranged from 50% to 76% among the free-living rural elderly subjects. Milk intake data that were collected from some of the subjects showed a significant correlation (P < 0.0001) between frequency of milk intake and riboflavin status. In a short-term riboflavin supplementation experiment in which nine riboflavin-deficient subjects were given 10 mg riboflavin/d for 3 d, all the subjects' EGRACs were normalized by the supplementation. However, they returned to a state of deficiency within 2 wk while consuming their usual diets without supplementation. It appears that the high prevalence of riboflavin deficiency in elderly Guatemalan people is caused by inadequate intake of riboflavin-rich foods such as dairy products, and that sufficient amounts of riboflavin need to be ingested regularly to maintain satisfactory riboflavin status.
Boisvert
W A
WA
USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111.
Castañeda
C
C
Mendoza
I
I
Langeloh
G
G
Solomons
N W
NW
Gershoff
S N
SN
Russell
R M
RM
D000368:Aged; D000818:Animals; D004032:Diet; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005980:Glutathione Reductase / Q000378:metabolism; D006166:Guatemala / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008892:Milk; D012256:Riboflavin / Q000008:administration & dosage; D012257:Riboflavin Deficiency / Q000453:epidemiology*
D005980:Glutathione Reductase; D012256:Riboflavin