title: The human leucine zipper-containing guanine-nucleotide exchange protein elongation factor-1 delta.
abstract: Copy-DNA clones containing the complete coding region of the human elongation factor-1 delta (EF-1 delta) mRNA have been isolated and characterized. We present the deduced amino acid sequence and observe in it a leucine zipper motif seen recently in EF-1 delta from Artemia and Xenopus laevis. The human EF-1 delta sequence shows a strong conservation in its C-terminal domain. The homology between the N-terminal domains of EF-1 delta proteins is low and almost exclusively limited to the leucine zipper motif.
authors.affiliation: Department of Medical Biochemistry, Sylvius Laboratory, Leiden, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Sanders
authors.forename: R
authors.initials: R
authors.lastname: Raggiaschi
authors.forename: J
authors.initials: J
authors.lastname: Morales
authors.forename: W
authors.initials: W
authors.lastname: Möller
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001156:Artemia / Q000235:genetics; D017124:Conserved Sequence; D020662:Guanine Nucleotide Exchange Factors; D006801:Humans; D016350:Leucine Zippers; D008969:Molecular Sequence Data; D020648:Peptide Elongation Factor 1; D010445:Peptide Elongation Factors / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment; D014982:Xenopus laevis / Q000235:genetics
chemical_list: D020662:Guanine Nucleotide Exchange Factors; D020648:Peptide Elongation Factor 1; D010445:Peptide Elongation Factors; D011506:Proteins