title: [Weber's syndrome of ischemic vascular origin--a clinical and neuroradiologic study].
abstract: A series of 4816 patients with cerebrovascular disease have undergone CT and/or MRI examinations over the last 25 years at the Higashi Nagoya National Hospital and the Nagoya National Hospital. Of these, we experienced 5 cases (4 men and 1 woman) of Weber's syndrome: two cases were resulted from cerebral embolism and three from cerebral thrombosis. All of the patients had left hemiparesis and right oculomotor palsy. On full investigation, complete unilateral external and internal oculomotor palsy was seen in two patients, while the remaining three patients showed pupillary sparing. The patients with complete oculomotor palsy presented with left hemiparesis as the initial symptom. In addition to oculomotor palsy and crossed hemiparesis, two patients had paralysis of the face and one patient had tongue muscle on the opposite side of the lesion and disorders of sensation. Positive Babinski's sign was found in four of the five patients. In one patient with unilateral glossoplegia on the side of hemiparesis, CT or MRI revealed a limited low-density or low signal intensity (T1) area in the inner part of the crus cerebri, and in the other patient who also had hemihypesthesia, the low-density or low-signal intensity (T1) area expanded into the dorsal midbrain. We would like concluded that the frequency of Weber's syndrome was very low though this syndrome was well celebrated, and the careful clinical observation of the neurological features of affected patients guided to the obvious site of lesion in the midbrain.
authors.affiliation: Department of Neurology, Higashi Nagoya National Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamana
authors.forename: N
authors.initials: N
authors.lastname: Murakami
authors.forename: E
authors.initials: E
authors.lastname: Itoh
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
mesh_terms: D000368:Aged; D002561:Cerebrovascular Disorders / Q000150:complications*; D005260:Female; D006429:Hemiplegia / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D013577:Syndrome; D014057:Tomography, X-Ray Computed