title: Personality disorders in cocaine dependence.
abstract: To assess the relationship between cocaine dependence and personality disorders, we administered the Structured Clinical Interview for DSM-III-R Personality Disorders (SCID-II) to 50 patients who were hospitalized for cocaine dependence. We modified the SCID-II so that patients were asked to indicate whether personality traits (if present) occurred during periods of drug use, abstinence, or both. Thirty-seven patients (74%) received at least one axis II diagnosis; 69% of these diagnoses were present both during periods of drug use and abstinence. Only one patient received a diagnosis during periods of drug use alone. These findings suggest that personality disorder diagnoses in cocaine-dependent patients remain relatively stable regardless of current drug use patterns. These data support clinicians' addressing these maladaptive personality traits as part of treatment for cocaine dependence.
authors.affiliation: Alcohol and Drug Abuse Program, McLean Hospital, Belmont.
authors.forename: R D
authors.initials: RD
authors.lastname: Weiss
authors.forename: S M
authors.initials: SM
authors.lastname: Mirin
authors.forename: M L
authors.initials: ML
authors.lastname: Griffin
authors.forename: J G
authors.initials: JG
authors.lastname: Gunderson
authors.forename: C
authors.initials: C
authors.lastname: Hufford
mesh_terms: D000328:Adult; D003042:Cocaine / Q000009:adverse effects*; D006760:Hospitalization; D006778:Hospitals, Psychiatric; D006801:Humans; D008297:Male; D010554:Personality Disorders / Q000145:classification / Q000175:diagnosis / Q000209:etiology*; D011569:Psychiatric Status Rating Scales; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000523:psychology* / Q000534:rehabilitation
chemical_list: D003042:Cocaine