Mucopolysaccharidosis IV A: assignment of the human N-acetylgalactosamine-6-sulfate sulfatase (GALNS) gene to chromosome 16q24.
Plasmid clones of three independent genomic fragments of the gene for human N-acetylgalactosamine-6-sulfate sulfatase (GALNS; EC 3.1.6.4) were utilized in a fluorescence in situ suppression hybridization study to assign the locus to chromosome 16q24. Enzyme assay for GALNS in a patient with del(16)(q22.1) confirmed this finding.
Masuno
M
M
Department of Pediatrics, Gifu University School of Medicine, Japan.
Tomatsu
S
S
Nakashima
Y
Y
Hori
T
T
Fukuda
S
S
Masue
M
M
Sukegawa
K
K
Orii
T
T
D015139:Blotting, Southern; D002811:Chondroitinsulfatases / Q000235:genetics*; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D003001:Cloning, Molecular; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D009085:Mucopolysaccharidosis IV / Q000235:genetics*; D010957:Plasmids
D002811:Chondroitinsulfatases