Chorionic villus sampling in a patient who is an unusual carrier of hemophilia B.
We describe a patient who is a carrier of hemophilia B, who was unusual in that she had symptoms and abnormal hematologic findings. She became pregnant and desired to have chorionic villus sampling for fetal sex determination. This was performed without complication. Her pregnancy continued, and she was delivered of a normal female infant with no complications for mother or infant. We believe this to be the first report of chorionic villus sampling in a symptomatic carrier of hemophilia B.
Shipley
C F
CF
Department of Obstetrics and Gynecology, University of South Carolina School of Medicine, Columbia 29203.
Nelson
G H
GH
D000328:Adult; D015193:Chorionic Villi Sampling; D005164:Factor IX / Q000032:analysis; D005260:Female; D002836:Hemophilia B / Q000175:diagnosis; D006579:Heterozygote; D006801:Humans; D010314:Partial Thromboplastin Time; D011247:Pregnancy; D011248:Pregnancy Complications; D012732:Sex Determination Analysis
D005164:Factor IX