title: New perspective in the treatment of low rectal cancer: total rectal resection and coloendoanal anastomosis.
abstract: OBJECTIVE
  Presently abdominoperineal resection still remains the most diffuse modality of treatment of low rectal cancer. However, a new surgical approach is now available to avoid such a demolitive surgery and a definitive colostomy.
  
  
  METHODS
  From March 1990 to March 1993, 58 total rectal resections were performed in 55 patients affected with primary or recurring cancers of the low rectum. As a restorative procedure, a colic J-shaped pouch and a handsewn pouch-endoanal anastomosis was adopted. All of the primary lesions were within 7 cm of the anal verge; in 74 percent the distal tumor margin was located less than 6 cm from the cutaneous edge.
  
  
  RESULTS
  Histologic clearance of the rectum cut edge was documented in all cases. Seven patients relapsed locally from 7 to 14 months after surgery and in 3 more cases distant metastases were documented. Postoperative morbidity is low. After colostomy closure in 78 percent of patients, perfect continence was achieved and in 74 percent less than two bowel movements a day were recorded. Fifty patients are presently alive, 46 without evidence of disease. The follow-up ranged from 2 to 37 (median, 13) months.
  
  
  CONCLUSIONS
  This experience, along with data obtained from last year's literature, indicates that a conservative surgical procedure, such as total rectal resection and coloendoanal anastomosis, can be considered a feasible and radical option for treatment of low rectal cancer.
authors.affiliation: Division of Surgical Oncology B, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Leo
authors.forename: F
authors.initials: F
authors.lastname: Belli
authors.forename: M T
authors.initials: MT
authors.lastname: Baldini
authors.forename: M
authors.initials: M
authors.lastname: Vitellaro
authors.forename: L
authors.initials: L
authors.lastname: Mascheroni
authors.forename: S
authors.initials: S
authors.lastname: Andreola
authors.forename: M
authors.initials: M
authors.lastname: Bellomi
authors.forename: R
authors.initials: R
authors.lastname: Zucali
mesh_terms: D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical; D003106:Colon / Q000601:surgery*; D003125:Colostomy; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011183:Postoperative Complications; D012004:Rectal Neoplasms / Q000601:surgery*; D012007:Rectum / Q000601:surgery