[Electroclinical manifestations elicited by intracerebral electric stimulation "shocks" in temporal lobe epilepsy].
In patients with severe drug-resistant partial epilepsy, undergoing Stereo-EEG investigations, spatial definition of the "epileptogenic area" is mainly based on spontaneous seizures recordings, but also on seizures induced by intracerebral electrical stimulation (ES). Only "trains" ES (TES, 50 pps) are currently used with this aim; "shocks" ES (SES, 1 pps) are principally applied to localize motor pathways. We have shown, during a prospective study concerning 10 temporal lobe epileptic patients, that SES could frequently induce seizures, especially when stimulation is applied in the anterior part of the Ammon's horn. Even if its efficacy seems lower than by TES, this kind of stimulation, in the majority of the cases, does reproduce isolated ictal subjective symptomatology, allowing the visualization of the progressive organisation of ictal electrical discharges, and avoids "unexpected" ("false positive"?) clinical responses.
Kahane
P
P
Département des neurosciences cliniques et biologiques, CHRU de Grenoble, France.
Tassi
L
L
Francione
S
S
Hoffmann
D
D
Lo Russo
G
G
Munari
C
C
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000503:physiopathology*; D002648:Child; D004558:Electric Stimulation; D004569:Electroencephalography; D004597:Electroshock; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors
Manifestations électrocliniques induites par la stimulation électrique intracérébrale par "chocs" dans les épilepsies temporales.