[Efficacy of antimicrobial prevention with single-dose ceftriaxone in urologic surgery].
One gm ceftriaxone was administered i.m. to 266 patients 1 h before urologic surgery. The antimicrobial spectrum and long half life of this beta-lactam make it potentially useful for prophylaxis. Its efficacy was determined by the incidence of infections and antibiotics required postoperatively. Postoperative bacteriuria was determined by two urine cultures: one at discharge from hospital or after catheter removal and another 4 weeks postoperatively. The overall postoperative infection rate was 9.7% and bacteriuria was 11.2%; most of these were asymptomatic. Antibiotics were administered postoperatively in 13.9% of the patients. The foregoing results corroborate the efficacy of this agent given in a single dose for prophylaxis against infection in urologic surgery.
Gallego Gómez
J
J
Servicio de Urología, Hospital General de Castellón, España.
Martínez García
R
R
Francisco Mingol
V
V
Llau Arcusa
L
L
Almela Tejedo
T
T
Ripoll Perello
J
J
D002443:Ceftriaxone / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D004724:Endoscopy / Q000009:adverse effects; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D011229:Preanesthetic Medication; D014552:Urinary Tract Infections / Q000382:microbiology / Q000517:prevention & control*; D014570:Urologic Diseases / Q000601:surgery*
D002443:Ceftriaxone
Eficacia de la profilaxis antimicrobiana con dosis única de ceftriaxona en cirugía urológica.