title: Application of magnetron sputtering for producing ceramic coatings on implant materials.
abstract: Radiofrequent magnetron sputtering was used to produce calcium phosphate coatings on metal and plastic substrates. Scanning electron microscopy showed that the deposited films had a uniform thickness and a dense columnar structure. Energy-dispersive X-ray analysis, X-ray crystal diffraction and atomic absorption spectrometry demonstrated that the sputtered layer was well-crystallized calcium phosphate ceramic with a Ca/P ratio varying between 1.9 and 2.5. The biocompatibility of the coatings was determined by in vitro and in vivo experiments. It was found that the coatings were biocompatible without any sign of adverse tissue reaction. It was concluded that magnetron sputtering is a promising method for forming a biocompatible ceramic coating onto an implant material. Nevertheless, several problems have to be solved before magnetron sputtering can be used on a routine basis for the production of Ca/P coatings.
authors.affiliation: Department of Oral Function and Prosthetic Dentistry, Laboratory of Biomaterials, Dental School, University of Nijmegen, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Jansen
authors.forename: J G
authors.initials: JG
authors.lastname: Wolke
authors.forename: S
authors.initials: S
authors.lastname: Swann
authors.forename: J P
authors.initials: JP
authors.lastname: Van der Waerden
authors.forename: K
authors.initials: K
authors.lastname: de Groot
mesh_terms: D000818:Animals; D015921:Dental Implants; D004577:Electron Probe Microanalysis; D006882:Hydroxyapatites; D008422:Materials Testing; D011817:Rabbits; D051381:Rats; D013054:Spectrophotometry, Atomic; D013499:Surface Properties; D014025:Titanium; D014961:X-Ray Diffraction
chemical_list: D015921:Dental Implants; D006882:Hydroxyapatites; D014025:Titanium