title: The greyhound dog as a model for studying pressure ulcers.
abstract: Because of their angular conformation, short hair, and thin skin, greyhounds are particularly subject to development of pressure ulcers. Greyhounds, therefore, can serve as a model to study pressure ulcers, either naturally occurring pressure ulcers or induced dermal pressure lesions. A method for inducing dermal pressure lesions was developed using a short-limb walking cast on one pelvic limb of the dog. Physical characteristics, dermal thromboxane B2 concentrations, and histopathologic changes were used to determine the severity of the lesions. Different lesion severities can be induced over the calcaneal tuberosity depending upon the amount of padding in the cast and the length of time the cast is in place. The technique for inducing a mild dermal pressure lesion is described.
authors.forename: S F
authors.initials: SF
authors.lastname: Swaim
authors.forename: D M
authors.initials: DM
authors.lastname: Bradley
authors.forename: D M
authors.initials: DM
authors.lastname: Vaughn
authors.forename: R D
authors.initials: RD
authors.lastname: Powers
authors.forename: C E
authors.initials: CE
authors.lastname: Hoffman
mesh_terms: D000818:Animals; D002370:Casts, Surgical; D004195:Disease Models, Animal; D004285:Dogs; D011312:Pressure; D003668:Pressure Ulcer / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D013929:Thromboxane B2 / Q000032:analysis
chemical_list: D013929:Thromboxane B2