Neutrophilic dermatosis associated with chronic neutrophilic leukemia.
Chronic neutrophilic leukemia is an uncommon myeloproliferative disorder. We report a new case that fulfills the clinical and biologic criteria for such a diagnosis. The hematologic disease was revealed by a neutrophilic dermatosis that finally disappeared spontaneously after a duration of 1 year. Despite the lack of parallelism in the course of dermatologic and hematologic manifestations, we believe they were strongly linked. Occurrence of neutrophilic dermatoses in the course of other myeloproliferative disorders is well known. However, in our case, clinical and histologic features could not be used to distinguish between atypical Sweet's syndrome and specific cutaneous lesions because of the mature appearance of both skin and blood neutrophils.
Castanet
J
J
Department of Dermatology, University of Nice, France.
Lacour
J P
JP
Garnier
G
G
Perrin
C
C
Taillan
B
B
Fuzibet
J G
JG
Ortonne
J P
JP
D000368:Aged; D006801:Humans; D015467:Leukemia, Neutrophilic, Chronic / Q000150:complications / Q000175:diagnosis*; D008297:Male; D009504:Neutrophils; D012871:Skin Diseases / Q000209:etiology*