title: High dose rate intracavitary brachytherapy of early and superficial carcinoma of the nasal vestibule as an alternative to low dose rate interstitial radiation therapy.
abstract: A new technique of high dose rate intracavitary brachytherapy is introduced for treating patients with early and superficial squamous cell carcinoma of the nasal vestibule. This method is illustrated by a case report. A customized intranasal mould was fabricated in which afterloading catheters were placed. These catheters were loaded with a high activity 192Ir pointsource, using the HDR-microSelectron. In this way the patient was treated twice daily over 5 days without hospitalization. The indications for the use of this technique and the advantages in comparison with low dose rate interstitial irradiation are discussed.
authors.affiliation: Institute of Radiotherapy, University of Nijmegen, The Netherlands.
authors.forename: L A
authors.initials: LA
authors.lastname: Pop
authors.forename: J H
authors.initials: JH
authors.lastname: Kaanders
authors.forename: E C
authors.initials: EC
authors.lastname: Heinerman
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D004867:Equipment Design; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D020366:Methylmethacrylate; D008768:Methylmethacrylates; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology / Q000528:radiation effects*; D009297:Nasal Mucosa / Q000528:radiation effects; D009669:Nose Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011879:Radiotherapy Dosage
chemical_list: D008768:Methylmethacrylates; D020366:Methylmethacrylate