A new pharmacological activity of dibutyl phthalate (DBP) on selective elimination of tumor cells from bone marrow.
DBP possesses a new pharmacological activity leading to selective deterioration of leukemic cells, with less harmful effect on the growth of normal hematopoietic progenitors.
Wu
C T
CT
Department of Experimental Hematology, Beijing Institute of Radiation Medicine, People's Republic of China.
Pei
X T
XT
Cao
J R
JR
Xue
H H
HH
D000208:Acute Disease; D001853:Bone Marrow / Q000187:drug effects* / Q000473:pathology; D001854:Bone Marrow Cells; D016465:Bone Marrow Purging; D002455:Cell Division / Q000187:drug effects; D003993:Dibutyl Phthalate / Q000494:pharmacology*; D006098:Granulocytes / Q000166:cytology; D006412:Hematopoietic Stem Cells / Q000187:drug effects; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy / Q000473:pathology*; D008264:Macrophages / Q000166:cytology; D014411:Neoplastic Stem Cells / Q000187:drug effects; D014407:Tumor Cells, Cultured
D003993:Dibutyl Phthalate