title: [Therapeutic problems in disseminated histiocytosis X].
abstract: The authors are dealing with the therapy problems of disseminated Langerhans cell histiocytosis on the basis of seven patients. In the treatment the combination of Vinblastine and Prednisolone was usually applied. The therapy was successful in four cases. The most significant prognostic factors were found to be the presence of organ dysfunction (mainly hepatic and pulmonary), the bone involvement and immunological parameters, respectively. Real therapy goals are stressed.
authors.affiliation: Borsod-Abaúj-Zemplén Megyei Kórház.
authors.forename: R
authors.initials: R
authors.lastname: Simkó
authors.forename: K
authors.initials: K
authors.lastname: Nagy
authors.forename: K
authors.initials: K
authors.lastname: Hunyadi
authors.forename: L
authors.initials: L
authors.lastname: Velkey
mesh_terms: D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008107:Liver Diseases / Q000209:etiology; D008171:Lung Diseases / Q000209:etiology; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D011379:Prognosis; D012074:Remission Induction; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D014747:Vinblastine; D011239:Prednisolone
vernacular_title: A disseminált histiocytosis X terápiás problémái.