[A genotypic study of children ill with tuberculosis and of healthy BCG-revaccinated ones of Tuvinian nationality].
The genotype was studied according to the 8 polymorphic genetic systems (Gm, Hp, Tf, Gc, ESD, PGM, ACP and ADA) in 73 children suffering from tuberculosis and 251 healthy children of the Tuvinian nationality. Analysis of the data obtained showed that a positive association was found in the allotype G1m (2), phenotype G1m (+1, +2, +4) and the genetic variant ESD 2-2 with tuberculosis in subjects of the Tuvinian nationality, and a negative association with the genotype ESD 1-1. It has been suggested that these genetic markers play a definite role in susceptibility to tuberculosis.
Matrakshin
A G
AG
Tsoĭ
K N
KN
Pospelov
L E
LE
Kapina
M A
MA
Kholod
O N
ON
Pushkina
E I
EI
D001500:BCG Vaccine / Q000276:immunology*; D002648:Child; D005260:Female; D005819:Genetic Markers; D005838:Genotype; D006801:Humans; D007117:Immunization, Secondary; D007129:Immunoglobulin Gm Allotypes / Q000235:genetics; D008297:Male; D011110:Polymorphism, Genetic; D012800:Siberia; D014397:Tuberculosis, Pulmonary / Q000208:ethnology / Q000235:genetics* / Q000517:prevention & control
D001500:BCG Vaccine; D005819:Genetic Markers; D007129:Immunoglobulin Gm Allotypes
Izuchenie genotipa u bol'nykh tuberkulezom i zdorovykh revaktsinirovannykh BTsZh deteĭ tuvinskoĭ natsional'nosti.