[The effect of alpha-1-acidic glycoprotein on neutrophil chemiluminescence and lipid peroxidation in experimental thermal trauma].
Induced chemoluminescence of neutrophils was distinctly inhibited both in intact mice and the animals with thermal injury after administration of acid alpha 1-glycoprotein. At the same time, the glycoprotein decreased the rate of thermal burn-induced activation of lipid peroxidation in rat blood, skin and liver tissue. Antioxidative and therapeutic effects of acid alpha 1-glycoprotein in burns appear to be related to regulation of neutrophil activity.
Salomatin
V V
VV
Liutov
A G
AG
Enikeeva
S A
SA
Charnaia
L F
LF
Zurochka
A V
AV
Dolgushin
I I
II
D000818:Animals; D002056:Burns / Q000188:drug therapy / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects; D008163:Luminescent Measurements; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009504:Neutrophils / Q000187:drug effects / Q000378:metabolism; D009961:Orosomucoid / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats
D009961:Orosomucoid
Vliianie alpha-1-kislogo glikoproteina na khemiliuminestsentsiiu neĭtrofilov i perekisnoe okislenie lipidov pri éksperimental'noĭ termicheskoĭ travme.