Effect of repeated exercise bouts on high density lipoprotein-cholesterol and its subfractions HDL2-C and HDL3-C.
Nine sedentary men (mean age, 22.8 yrs) were studied during and after treadmill exercise at 65% VO2max to determine the number of repeated exercise bouts required to bring about a sustained elevation in HDL-cholesterol and its subfraction HDL2-C and HDL3-C. A Latin square counterbalanced design was used. Thirty minute exercise sessions were undertaken in the following patterns: (1) single bout, (2) two bouts on alternate days, and (3) three bouts on alternate days. The exercise bouts in patterns 2 and 3 were separated by 48 h. Patterns 1, 2 and 3 were conducted 7 days apart. Blood samples were obtained prior to each pattern and at 5 min, 24 and 48 h after the last session within each pattern. There were no significant differences in triglycerides and total cholesterol between the selected blood sampling points for all patterns. Total HDL-C remained higher (p < 0.05) than the pre-exercise level 5 min [pattern 1: 39.0 vs 41.2 mg.dl-1, pattern 2: 37.1 vs 39.2 mg.dl-1, pattern 3: 38.8 vs 42.7 mg.dl-1] and 24 h [pattern 1: 39.0 vs 39.4 mg.dl-1, pattern 2: 37.1 vs 39.1 mg.dl-1, pattern 3: 38.8 vs 42.6 mg.dl-1] post-exercise. Total HDL-C declined to pre-exercise values 48 h post-exercise in all patterns. HDL2-C was lower (p < 0.05) than pre-exercise 48 h for all exercise patterns. For all patterns, HDL3-C levels were higher (p < 0.05) at the 5 min and 48 h post-exercise time points than at the pre-exercise.(ABSTRACT TRUNCATED AT 250 WORDS)
Angelopoulos
T J
TJ
Human Energy Research Laboratory, University of Pittsburgh, PA 15261.
Robertson
R J
RJ
Goss
F L
FL
Metz
K F
KF
LaPorte
R E
RE
D000328:Adult; D001823:Body Composition; D008076:Cholesterol, HDL / Q000097:blood*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3; D008297:Male; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D008075:Lipoproteins, HDL; D053439:Lipoproteins, HDL2; D053440:Lipoproteins, HDL3; D014280:Triglycerides