title: [The expanded ileal pouch as a reservoir in continence preserving proctocolectomy. An experimental study on the pig].
abstract: Silicone balloons were inserted into bypassed segments of terminal ileum of five mini-pigs. The balloons were expanded over a period of 3 months, thereby creating pouches with a mean volume of 700 cm3 (a 9.5-fold increase). Functional proctocolectomy was performed and the bypassed segment was than placed in continuity with its terminal end at the previous site of the anus, thus creating a neorectum. One year later, the three pigs were still alive. They were continent and stool frequency was 2-3 times a day. The final mean volume of the pouch was still 360 cm3, corresponding to a 5.7-fold increase. At the end of the experiment significant hypertrophy of the bowel wall thickness was observed compared to the controls. The rectal X-ray contrast study demonstrated a new rectal reservoir without fistula or stenosis.
authors.affiliation: Klinik für Plastische und Wiederherstellungschirurgie, Handchirurgie, Schwerstverbranntenzentrum, Köln-Merheim.
authors.forename: A
authors.initials: A
authors.lastname: Dorer
authors.forename: K J
authors.initials: KJ
authors.lastname: Walgenbach
authors.forename: G B
authors.initials: GB
authors.lastname: Stark
authors.forename: A
authors.initials: A
authors.lastname: Hirner
mesh_terms: D000818:Animals; D003093:Colitis, Ulcerative / Q000601:surgery*; D003111:Colonic Polyps / Q000601:surgery*; D003672:Defecation / Q000502:physiology; D005242:Fecal Incontinence / Q000517:prevention & control; D016737:Proctocolectomy, Restorative / Q000379:methods*; D013536:Suture Techniques; D013552:Swine; D013556:Swine, Miniature; D014945:Wound Healing / Q000502:physiology
vernacular_title: Die expandierte Ileumschlinge als Reservoir bei kontinenzerhaltender Proktokolektomie. Eine experimentelle Studie am Schwein.