[Calcium protein signaling].
Calcium ion is thought to play an important role in the intracellular signal transduction system and transfer its information through Ca(2+)-receptive proteins. Among many calcium receptive proteins, EF-hand type calcium receptive protein family are being investigated quite extensively. Calmodulin, one of representative EF-hand protein, localizes ubiquitously in many cells and tissues. This protein is involved in a general signal transduction system, such as, cell proliferation and differentiation. On the other hand, S-100 protein are distributed in specific cells and play specified roles.
Hidaka
H
H
Department of Pharmacology, Nagoya University School of Medicine.
Watanabe
M
M
D000595:Amino Acid Sequence; D000818:Animals; D002118:Calcium / Q000502:physiology*; D002135:Calcium-Binding Proteins / Q000737:chemistry / Q000502:physiology; D002147:Calmodulin / Q000502:physiology; D018797:Cell Cycle Proteins; D002454:Cell Differentiation; D002455:Cell Division; D006801:Humans; D008969:Molecular Sequence Data; D000075383:S100 Calcium Binding Protein A6; D000071999:S100 Calcium-Binding Protein A4; D009418:S100 Proteins / Q000502:physiology; D015398:Signal Transduction
D002135:Calcium-Binding Proteins; D002147:Calmodulin; D018797:Cell Cycle Proteins; D000075383:S100 Calcium Binding Protein A6; D000071999:S100 Calcium-Binding Protein A4; D009418:S100 Proteins; C055351:S100A6 protein, human; C077591:S100A4 protein, human; D002118:Calcium