title: In vitro methods for assessing human hepatic drug metabolism: their use in drug development.
authors.affiliation: Department of Drug Metabolism, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.
authors.forename: S A
authors.initials: SA
authors.lastname: Wrighton
authors.forename: M
authors.initials: M
authors.lastname: Vandenbranden
authors.forename: J C
authors.initials: JC
authors.lastname: Stevens
authors.forename: L A
authors.initials: LA
authors.lastname: Shipley
authors.forename: B J
authors.initials: BJ
authors.lastname: Ring
authors.forename: A E
authors.initials: AE
authors.lastname: Rettie
authors.forename: J R
authors.initials: JR
authors.lastname: Cashman
mesh_terms: D003577:Cytochrome P-450 Enzyme System / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism* / Q000648:ultrastructure; D010105:Oxygenases / Q000502:physiology; D004364:Pharmaceutical Preparations / Q000378:metabolism*
chemical_list: D004364:Pharmaceutical Preparations; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases; C020066:dimethylaniline monooxygenase (N-oxide forming)