Evaluation of pulmonary vascular anatomy and blood flow by magnetic resonance.
Rapidly evolving magnetic resonance (MR) imaging techniques provide noninvasive approaches to evaluating morphology and quantitative physiologic information about blood flow in the pulmonary circulation. Important clinical applications currently include the preoperative and postoperative evaluation of congenital abnormalities, assessment of vascular involvement by extrinsic and intrinsic tumors, identification of central thromboemboli, and diagnosis of vascular lung lesions. Ongoing refinements in pulmonary MR angiography may make it possible to use the technique for the noninvasive detection of acute pulmonary emboli in the near future. Quantitative measurements based upon MR flow-encoding sequences are promising for the evaluation of patients with abnormal degrees or distributions of pulmonary blood flow, for example, those with unilateral lung transplants or pulmonary arterial stenoses. MR contrast agents currently under development also show promise for quantitative measurements of regional pulmonary ventilation and perfusion. The coupling of high-resolution anatomic and functional images renders MR a uniquely attractive and powerful method for evaluating the pulmonary vasculature.
Gefter
W B
WB
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Hatabu
H
H
D006801:Humans; D008168:Lung / Q000098:blood supply*; D008279:Magnetic Resonance Imaging / Q000379:methods; D011652:Pulmonary Circulation / Q000502:physiology*; D012039:Regional Blood Flow / Q000502:physiology