title: Sib-pair linkage analyses of Alzheimer's disease.
abstract: Sib-pair linkage analyses were used to search for linkage to a set of chromosome 19 and 21 marker loci in two sets of families with Alzheimer's disease. The advantage of this technique is that no assumption is made about the mode of inheritance of the disease. Some mild suggestions of linkage were found in early-onset families for a chromosome 21 marker and in a set of late-onset families for a chromosome 19 marker.
authors.affiliation: Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans 70112.
authors.forename: J E
authors.initials: JE
authors.lastname: Bailey-Wilson
authors.forename: V
authors.initials: V
authors.lastname: Bamba
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000453:epidemiology / Q000235:genetics*; D001900:Boston / Q000453:epidemiology; D002869:Chromosome Aberrations / Q000453:epidemiology / Q000235:genetics; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19; D002891:Chromosomes, Human, Pair 21; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008875:Middle Aged; D009657:North Carolina / Q000453:epidemiology
chemical_list: D005819:Genetic Markers