title: Screening for cephalosporin-resistant Streptococcus pneumoniae with the Kirby-Bauer disk susceptibility test.
abstract: Kirby-Bauer disk susceptibility tests with five standard cephalosporin disks were performed on 23 penicillin-resistant Streptococcus pneumoniae isolates for which ceftriaxone MICs were 0.125 to 4 micrograms/ml. Cefuroxime disk inhibition zone diameters distinguished clearly isolates for which ceftriaxone MICs were > or = 2 micrograms/ml from more susceptible strains, whereas cephalothin, ceftizoxime, cefotaxime, and ceftriaxone disks distinguished these isolates less clearly than the cefuroxime disk did.
authors.affiliation: Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9063.
authors.forename: I R
authors.initials: IR
authors.lastname: Friedland
authors.forename: S
authors.initials: S
authors.lastname: Shelton
authors.forename: G H
authors.initials: GH
authors.lastname: McCracken
mesh_terms: D002443:Ceftriaxone / Q000494:pharmacology; D002444:Cefuroxime / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D002648:Child; D004352:Drug Resistance, Microbial; D005069:Evaluation Studies as Topic; D006801:Humans; D008586:Meningitis, Pneumococcal / Q000188:drug therapy / Q000382:microbiology; D008826:Microbial Sensitivity Tests / Q000379:methods*; D010403:Penicillin Resistance; D013296:Streptococcus pneumoniae / Q000187:drug effects*
chemical_list: D002511:Cephalosporins; D002443:Ceftriaxone; D002444:Cefuroxime