MRI of choroidal plexus involvement in intracranial cryptococcosis.
OBJECTIVE
The sensitivity of medical imaging in the diagnosis of intracranial cryptococcosis is poor. MRI can provide additional information in establishing this diagnosis.


METHODS
We present two cases of CNS cryptococcosis (HIV negative) studied by MRI and discuss the involvement of the ventricles and the choroid plexuses.


RESULTS
The choroid plexuses are unusually enlarged and they enhance intensely. Intraventricular loculations were also noted including entrapment of CSF in the temporal horns.


CONCLUSIONS
The constellation of these findings is highly suggestive of cryptococcosis.
Patronas
N J
NJ
Department of Radiology, National Institutes of Health, Bethesda, MD 20892.
Makariou
E V
EV
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D002831:Choroid Plexus / Q000473:pathology*; D003287:Contrast Media; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy; D004338:Drug Combinations; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008536:Meglumine; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D012680:Sensitivity and Specificity
D003287:Contrast Media; D004338:Drug Combinations; D009942:Organometallic Compounds; D008536:Meglumine; D004369:Pentetic Acid; D000666:Amphotericin B; D019786:Gadolinium DTPA