[Anti-free-radical damaging action of panaxadiol saponins and panaxatriol saponins on the myocardial contractibility of the isolated rat working heart].
Rats were free-radical-damaged by xanthine 6.4 mg.100g-1.d-1 and xanthine oxidase 0.1U.100g-1d-1 to cause significant decrease in the cardiac functional parameters. Panaxatriol saponins 10mg.100g-1.d-1 converted all the indices toward normal without exception. Panaxadiol saponins were more effective than panaxatriol saponins.
Wang
X M
XM
Norman Bethune University of Medical Sciences, Changchun.
Jiang
Y
Y
Zhong
G G
GG
Sun
X X
XX
D000818:Animals; D005260:Female; D016166:Free Radical Scavengers; D036145:Ginsenosides; D006439:Hemodynamics / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D014315:Triterpenes / Q000494:pharmacology*
D016166:Free Radical Scavengers; D036145:Ginsenosides; D014315:Triterpenes; C004564:panaxadiol; C004563:panaxatriol