Gastric mucosa in acute viral hepatitis.
In acute viral hepatitis, gastric biopsy and augmented histamine test were performed in 63 patients. Gastric histology was abnormal in 12 of 63 (19%) patients; 3 with superficial and 9 with atrophic gastritis. Maximal acid output was less than 10 mEq/h in 35 of 63 (55.5%) patients. Acid load tests were performed in 23 patients measuring H+, K+, Na+ fluxes; the results showed increased loss of acid from lumen to mucosa in 16 of 23 (69.6%) patients, indicating damage to the gastric mucosal barrier.
Contractor
Q Q
QQ
Department of Gastroenterology, BYL Nair Charitable Hospital, Bombay.
Zaveri
M P
MP
Kalro
R H
RH
Desai
H G
HG
D000208:Acute Disease; D000328:Adult; D001706:Biopsy; D005744:Gastric Acid / Q000378:metabolism*; D005753:Gastric Mucosa / Q000473:pathology*; D005757:Gastritis, Atrophic / Q000209:etiology* / Q000473:pathology; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000473:pathology; D006632:Histamine / Q000031:analogs & derivatives; D006801:Humans
D006632:Histamine; C027556:histamine phosphate