Primary malignant lymphoma of the uterus: localization in a cervical polyp.
Distinction between benign and malignant lymphoid lesions of the uterine cervix can be difficult. Two patients showing atypical lymphoid tissue confined to a uterine cervical polyp are presented. In one patient a non-Hodgkin lymphoma stage IE was diagnosed. Treatment consisted of combination chemotherapy. In a second patient the lesion was classified as atypical lymphoid hyperplasia. No treatment was initiated. The presence of a non-Hodgkin lymphoma in a cervical polyp is extremely rare. Distinction between benign and malignant lymphoid tissue within a cervical polyp can be facilitated by immunohistochemical staining and application of the histological criteria for a reactive nature of such lesions.
Broekmans
F J
FJ
Department of Obstetrics and Gynecology, Free University Hospital, Amsterdam, The Netherlands.
Swartjes
J M
JM
Van der Valk
P
P
Schutter
E M
EM
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002584:Cervix Uteri / Q000473:pathology*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007150:Immunohistochemistry; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000473:pathology*; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology*; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone; D008727:Methotrexate