title: Occurrence of paroxysmal synchronous EEG discharges in subcortical arteriosclerotic encephalopathy (Binswanger's disease).
abstract: A 72-year-old patient with von Recklinghausen's disease showed akinetic mutism within 6 months of the onset of dementia. The findings of diffuse cerebral atrophy on CT and periodic synchronous discharges (PSDs) in EEG suggested Creutzfeldt-Jakob disease. However, autopsy findings of diffuse softening of the subcortical white matter and marked arteriosclerotic changes of the subcortical arterioles with sparing of the cortex in the cerebrum confirmed a diagnosis of Binswanger's disease. Binswanger's disease should be included in the differential diagnosis of dementia showing PSDs in EEG.
authors.affiliation: Department of Internal Medicine, Saga Medical School, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kuroda
authors.forename: A
authors.initials: A
authors.lastname: Ikeda
authors.forename: K
authors.initials: K
authors.lastname: Kurohara
authors.forename: R
authors.initials: R
authors.lastname: Kakigi
authors.forename: S
authors.initials: S
authors.lastname: Ryuh
authors.forename: H
authors.initials: H
authors.lastname: Kouda
authors.forename: N
authors.initials: N
authors.lastname: Misago
authors.forename: H
authors.initials: H
authors.lastname: Sugihara
mesh_terms: D000368:Aged; D001344:Autopsy; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D015140:Dementia, Vascular / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D006801:Humans; D008297:Male; D017253:Neurofibromatoses / Q000150:complications