title: Differential permeance of retina and retinal pigment epithelium to water: implications for retinal adhesion.
abstract: Water movement from the vitreous to the choroid would tend to maintain retinal apposition, if the retina were less permeable than the retinal pigment epithelium (RPE). We used a rabbit model, to test the relative permeability of retina and RPE to tritiated water. The retina was found less permeable than the RPE. This result suggests the presence of a hydrostatic pressure gradient across the retina which could enhance apposition of retina to the RPE.
authors.affiliation: Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles.
authors.forename: B
authors.initials: B
authors.lastname: Kirchhof
authors.forename: S J
authors.initials: SJ
authors.lastname: Ryan
mesh_terms: D000818:Animals; D001692:Biological Transport; D002463:Cell Membrane Permeability / Q000502:physiology; D004195:Disease Models, Animal; D010857:Pigment Epithelium of Eye / Q000378:metabolism*; D011817:Rabbits; D012160:Retina / Q000378:metabolism*; D012164:Retinal Diseases / Q000209:etiology* / Q000378:metabolism; D012167:Retinal Perforations / Q000378:metabolism; D000267:Tissue Adhesions / Q000209:etiology; D014821:Vitrectomy; D014822:Vitreous Body / Q000378:metabolism; D014867:Water / Q000378:metabolism*
chemical_list: D014867:Water