title: The INO1 promoter of Saccharomyces cerevisiae includes an upstream repressor sequence (URS1) common to a diverse set of yeast genes.
abstract: The INO1 promoter of Saccharomyces cerevisiae includes a copy of an upstream repression sequence (URS1; 5'AGCCGCCGA 3') observed in the promoters of several unrelated yeast genes. Expression of INO1-lacZ and CYC1-lacI'Z, activated by the INO1 UASINO, is significantly decreased by the INO1 URS1.
authors.affiliation: Department of Molecular and Cellular Biochemistry, Stritch School of Medicine, Loyola University, Chicago, Maywood, Illinois 60153.
authors.forename: J M
authors.initials: JM
authors.lastname: Lopes
authors.forename: K L
authors.initials: KL
authors.lastname: Schulze
authors.forename: J W
authors.initials: JW
authors.lastname: Yates
authors.forename: J P
authors.initials: JP
authors.lastname: Hirsch
authors.forename: S A
authors.initials: SA
authors.lastname: Henry
mesh_terms: D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000378:metabolism; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal / Q000235:genetics*; D008969:Molecular Sequence Data; D007296:Myo-Inositol-1-Phosphate Synthase / Q000096:biosynthesis / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics*; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004268:DNA-Binding Proteins; D011993:Recombinant Fusion Proteins; D007296:Myo-Inositol-1-Phosphate Synthase