title: Standardization of enzyme determinations: process and outcome.
abstract: Standardization of enzyme measurements grew out of an unsatisfactory situation in the late 1960's. More national and regional professional groups began a process based on standardization of methodologies. Experiences from these national efforts were utilized by the International Federation of Clinical Chemistry as part of a development of international reference methods. Based on these modified routine methods were suggested and implemented. A last brick in the system is the production of certified reference materials. Together these components comprise a consistent system for measurement of the catalytic activity of enzymes.
authors.affiliation: Department of Clinical Chemistry, Odense University Hospital, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Hørder
mesh_terms: D002624:Chemistry, Clinical / Q000379:methods / Q000592:standards*; D004798:Enzymes / Q000032:analysis* / Q000097:blood; D006801:Humans; D007391:International Cooperation; D012015:Reference Standards; D012537:Scandinavian and Nordic Countries
chemical_list: D004798:Enzymes