Measuring the rupture stress point of biological sealant-collagen bonding: validation of a technique used after hepatectomy.
The aim of this experimental study was to measure the rupture stress point of a fibrin clot situated on a liver, in realistic surgical conditions. The experimental method was carried out with a machined wooden cylinder bonded on the liver, connected with a wire to a setup and pulled at a constant speed, and a sensor was placed on the wire measuring the applied strength. This method, realized in the dog, made it possible to validate a precise and reproducible method designed for testing the adhesive characteristics of biological sealant-collagen bonding on the liver.
Michot
F
F
Groupe de Biochimie et Physiopathologie Digestive et Nutritionnelle, Hôpital Charles-Nicolle, Rouen, France.
Scotte
M
M
Dujardin
F
F
Hoebeke
Y
Y
Le Blanc
I
I
Amelot
A
A
Azema
P
P
Bouvier
P
P
D000268:Adhesiveness; D000818:Animals; D003094:Collagen; D004285:Dogs; D015718:Fibrin Tissue Adhesive / Q000494:pharmacology*; D006498:Hepatectomy / Q000379:methods*; D013718:Tensile Strength
D015718:Fibrin Tissue Adhesive; D003094:Collagen