title: Biology of chronic radiation effect on tissues and wound healing.
abstract: Radiation therapy exerts both acute and chronic effects on normal tissue included within treatment fields. The physics of radiation therapy and treatment techniques to minimize deleterious effects of radiation are presented. Management of radiation-damaged skin is discussed. Radiation effect on tissue, wound healing, and tumorigenesis also are reviewed.
authors.affiliation: Department of Dermatology, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: E F
authors.initials: EF
authors.lastname: Bernstein
authors.forename: F J
authors.initials: FJ
authors.lastname: Sullivan
authors.forename: J B
authors.initials: JB
authors.lastname: Mitchell
authors.forename: G D
authors.initials: GD
authors.lastname: Salomon
authors.forename: E
authors.initials: E
authors.lastname: Glatstein
mesh_terms: D000818:Animals; D006801:Humans; D009381:Neoplasms, Radiation-Induced; D011853:Radiobiology; D011878:Radiotherapy / Q000009:adverse effects* / Q000379:methods; D012867:Skin / Q000528:radiation effects; D012878:Skin Neoplasms / Q000209:etiology; D014945:Wound Healing / Q000528:radiation effects*