title: [Curative effect of combined traditional Chinese medicine with Western medicine therapy on chronic nephritis and its correlation with hemorheology and microcirculation].
abstract: Patients were divided into two groups, 89 cases treated by combined traditional Chinese and Western medicine (TCM-WM) therapy, the other 36 served as control. Each of two groups was further subdivided into 4 clinical types and 5 Syndromes of TCM. Hemorheology and microcirculation were tested before and after treatment, the clinical curative effects of both groups were compared and correlation analysis between clinical curative effect and improvement of hemorheology and microcirculation was made. The results showed that the remission rate and total effective rate were 79.8% and 92.1% respectively in testing group, significantly higher than those (25% and 50%) of control (P < 0.05-0.01). The curative effect on each clinical type and Syndrome of TCM was better than that on corresponding type and Syndrome of control (P < 0.05-0.01). The improvement of hemorheology and microcirculation was more significant in testing group than that in control. It was very significant in complete and partial remission of both group (P < 0.05-0.01) but not marked in the cases of improved and ineffective cases (P > 0.05). Therefore clinical curative effect was closely related with them. So any treatment which could improve hemorheology and microcirculation would be useful in treating chronic nephritis.
authors.affiliation: Hebei Provincial Hospital, Shijiazhuang.
authors.forename: G X
authors.initials: GX
authors.lastname: Sun
mesh_terms: D000328:Adult; D001809:Blood Viscosity / Q000187:drug effects; D002908:Chronic Disease; D004176:Dipyridamole / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D009262:Nails / Q000098:blood supply*; D009393:Nephritis / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D012212:Rheology
chemical_list: D004365:Drugs, Chinese Herbal; D004176:Dipyridamole