title: Predictive value of uterine Doppler waveform during pregnancies complicated by diabetes.
abstract: Diabetes, whether or not it is insulin deficient, is frequently associated with vascular complications during pregnancies. It is accepted nowadays that the uterine artery velocity waveform is predictive concerning pregnancy-induced hypertension (PIH) and its complications. It thus seemed interesting to analyse the predictivity of vascular complications of diabetes by using uterine artery velocity waveforms. We have thus explored 37 diabetic patients [group 1: insulin-deficient diabetes (IDD), n = 10; group 2: gestational IDD, n = 6; and gestational non-IDD, n = 21). We have found vascular complications for 10 patients, divided between all 2 groups: 2 pre-eclampsia, 2 fetal suffering before any labour, 2 cases of intra-uterine growth retardation (including a trisomy 18) and 5 PIH. The uterine artery velocimetry measurement has been found to be pathological 5 times, and always in patients who later developed vascular complications. Among this selected population and excluding the trisomy 18, the sensitivity is of 44.5%, the specificity of 100%, the positive predictive value of 100%, and the negative predictive value of 84.3%. If these results are confirmed, this examination could be an excellent marker of the vascular risk and thus would have its place during systematic survey of pregnancies complicated by diabetes.
authors.affiliation: Clinique Universitaire. Baudelocque-Port Royal, Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Haddad
authors.forename: M
authors.initials: M
authors.lastname: Uzan
authors.forename: C
authors.initials: C
authors.lastname: Tchobroutsky
authors.forename: S
authors.initials: S
authors.lastname: Uzan
authors.forename: E
authors.initials: E
authors.lastname: Papiernik-Berkhauer
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000000981:diagnostic imaging / Q000503:physiopathology; D016640:Diabetes, Gestational / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D005317:Fetal Growth Retardation / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D011225:Pre-Eclampsia / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000000981:diagnostic imaging* / Q000503:physiopathology; D014314:Trisomy; D014463:Ultrasonography; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging*