title: Hip disease in adults with Down syndrome.
abstract: The life expectancy of patients with Down syndrome has increased significantly in recent years. Hip abnormalities occur in children with this syndrome but little is known about their natural history in later life. In 65 adults with Down syndrome we found hip abnormalities in 28%, and this was statistically correlated with walking ability. A subgroup of 18 patients was followed by serial examination; this showed that hip instability occurred in adulthood and became worse with time. In some patients, hip instability started after skeletal maturity.
authors.affiliation: Tufts University School of Medicine, Boston, Massachusetts 02111.
authors.forename: M T
authors.initials: MT
authors.lastname: Hresko
authors.forename: J C
authors.initials: JC
authors.lastname: McCarthy
authors.forename: M J
authors.initials: MJ
authors.lastname: Goldberg
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D004314:Down Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology; D005260:Female; D006618:Hip Dislocation, Congenital / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007593:Joint Instability / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008297:Male; D008404:Massachusetts / Q000453:epidemiology; D008875:Middle Aged; D011859:Radiography; D016138:Walking