Separation of 21-(R)- and 21-(S)-argatroban: solubility and activity of the individual diastereoisomers.
Rawson
T E
TE
VanGorp
K A
KA
Yang
J
J
Kogan
T P
TP
D000818:Animals; D000991:Antithrombins / Q000737:chemistry / Q000302:isolation & purification*; D001120:Arginine / Q000031:analogs & derivatives; D001777:Blood Coagulation / Q000187:drug effects; D002417:Cattle; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D007536:Isomerism; D010875:Pipecolic Acids / Q000737:chemistry / Q000302:isolation & purification*; D012995:Solubility; D013449:Sulfonamides
D000991:Antithrombins; D010875:Pipecolic Acids; D013449:Sulfonamides; D001120:Arginine; C031942:argatroban