High dose tamoxifen in the treatment of recurrent high grade glioma: a report of clinical stabilization and tumour regression.
We present a case of recurrent glioma, previously treated with maximal surgery and radiation in which a high dose of tamoxifen has stabilized the tumour clinically and has resulted in it's radiologic regression. Given tamoxifen's relative lack of toxicity, it might serve as a useful adjuvant in the treatment of recurrent glioma.
Baltuch
G
G
Department of Neurology and Neurosurgery, McGill University, Montreal.
Shenouda
G
G
Langleben
A
A
Villemure
J G
JG
D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005625:Frontal Lobe / Q000000981:diagnostic imaging* / Q000473:pathology; D005910:Glioma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012008:Recurrence; D013629:Tamoxifen / Q000008:administration & dosage / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
D013629:Tamoxifen