Extensive osteolysis around an aseptic, stable, uncemented total knee replacement.
Extensive osteolysis occurred around an aseptic, well-fixed, stable, uncemented total knee prosthesis. At the time of revision, tibial polyethylene wear and minimal metal-on-metal contact were present. A hypertrophic synovium-like membrane abutted bone in regions of osteolysis. Examination of this membrane revealed polyethylene-wear debris and significant levels of chromium, cobalt, and titanium. Wear debris--polyethylene, metal, or a combination of both--may be responsible for the osteolytic process in this case.
Berry
D J
DJ
Department of Orthopedics, Mayo Clinic, Rochester, Minnesota 55905.
Wold
L E
LE
Rand
J A
JA
D001843:Bone Cements; D002857:Chromium / Q000032:analysis; D003035:Cobalt / Q000032:analysis; D005269:Femur / Q000473:pathology*; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000209:etiology* / Q000473:pathology; D011095:Polyethylenes / Q000032:analysis; D011475:Prosthesis Failure; D013583:Synovial Membrane / Q000737:chemistry; D014025:Titanium / Q000032:analysis
D001843:Bone Cements; D011095:Polyethylenes; D002857:Chromium; D003035:Cobalt; D014025:Titanium