Bilateral carcinoma of the breast.
In a retrospective review of 2820 patients with breast carcinoma seen at the Combined Breast Clinic of St George's Hospital over a 23-year period 101 cases were bilateral of which 52 (1.8%) presented synchronously and 49 (1.7%) metachronously. Twenty deaths occurred in the synchronous group after a mean follow-up of 56.2 months and 15 deaths in the metachronous group after a mean follow-up of 48.5 months following diagnosis of the second tumour. If timed from initial presentation patients with metachronous tumours fared better than those with unilateral disease (P < 0.01). There was no significant difference in survival between patients with metachronous (if timed from the second tumour), synchronous or unilateral breast carcinoma.
Graham
M D
MD
Surgical Breast Unit, St George's Hospital, Tooting, London.
Yelland
A
A
Peacock
J
J
Beck
N
N
Ford
H
H
Gazet
J C
JC
D001943:Breast Neoplasms; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D016609:Neoplasms, Second Primary; D012189:Retrospective Studies; D016019:Survival Analysis