title: Minocycline instillation for lymphorrhea after extraperitoneal pelvic lymphadenectomy. OFF.
abstract: We managed four cases of lymphorrhea after extraperitoneal pelvic lymphadenectomy by means of minocycline instillation into the cavity around the drainage tube. Two patients had concomitantly undergone cystectomy and one prostatectomy via the extraperitoneal approach. In all four cases, the lymphorrhea markedly subsided, which dramatically shortened the duration of drainage. No side effects occurred. These findings indicate that minocycline instillation is an efficacious treatment for lymphorrhea.
authors.affiliation: Department of Urology, Nagoya University School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Okamura
authors.forename: O
authors.initials: O
authors.lastname: Kuriki
authors.forename: Y
authors.initials: Y
authors.lastname: Nakano
authors.forename: J
authors.initials: J
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Shimoji
authors.forename: K
authors.initials: K
authors.lastname: Miyake
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D015653:Cystectomy; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects* / Q000379:methods; D008206:Lymphatic Diseases / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008911:Minocycline / Q000008:administration & dosage*; D010388:Pelvis; D011468:Prostatectomy
chemical_list: D008911:Minocycline