title: Comments on the Health Effects Institute-Asbestos Research (HEI-AR) report: "Asbestos in public and commercial buildings," with emphasis on risk assessment methods used.
abstract: A Health Effects Institute--Asbestos Research Report calculates the risk of exposure to environmental asbestos fibers (EAF) by downward extrapolation from the mortality of workers exposed for 20 years. This extrapolation is improper because 1) relative risks of asbestos exposure very likely are not linearly progressive; 2) the composition of EAF may not be equivalent to that in mining or fabricating; 3) the same environmental asbestos concentration probably represents different exposure doses for different populations; and 4) health effects of asbestos exposure on children, seniors, patients, the institutionalized, the handicapped, and the chronically ill may not be the same as those of healthy workers. Evidence of asbestos-related disease among family members of exposed workers demonstrates that the risk observed for EAF is substantially larger than that estimated from downward extrapolation and suggests a basis for an alternative approach to estimating asbestos-related health risks. Such epidemiologic procedures are well established and ought to form the basis for detecting the health effects of EAF. It is also unclear which industry supports HEI-AR.
authors.affiliation: School of Computing Science, Faculty of Applied Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
authors.forename: T D
authors.initials: TD
authors.lastname: Sterling
authors.forename: C W
authors.initials: CW
authors.lastname: Collett
authors.forename: W L
authors.initials: WL
authors.lastname: Rosenbaum
authors.forename: J J
authors.initials: JJ
authors.lastname: Weinkam
mesh_terms: D000047:Academies and Institutes; D000368:Aged; D001194:Asbestos / Q000009:adverse effects*; D015982:Bias; D002648:Child; D004781:Environmental Exposure; D004812:Epidemiologic Methods; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology; D012306:Risk
chemical_list: D001194:Asbestos