A ferric calcium phosphorous oxide (FECAP) ceramic for rebuilding bone.
A ferric-calcium-phosphorous oxide ceramic (FECAP) was fabricated for repairing traumatized bone. Seventy-two Sprague-Dawley rats were distributed into three groups: non-operated controls, sham-operated, and FECAP implanted animals. A 4 mm hole was drilled into the diaphysial ridge communicating with the medullary canal in the femurs of sham-operated and experimental animals. In the experimental animals, the hole was packed with 0.25 g of FECAP ceramic particles. Eight animals from each group were sacrificed at 15, 30, and 45 days. Morphological examination and analysis of blood data, body weights, and organ:body weight ratios indicated that FECAP ceramics can be used as non toxic bone substitutes.
Larrabee
R A
RA
Department of Biology, University of Dayton, OH 45469-2320.
Fuski
M P
MP
Bajpai
P K
PK
D000818:Animals; D001672:Biocompatible Materials; D001835:Body Weight; D001842:Bone and Bones / Q000601:surgery*; D002516:Ceramics / Q000737:chemistry; D019736:Prostheses and Implants; D051381:Rats; D017207:Rats, Sprague-Dawley
D001672:Biocompatible Materials