Fatigue in systemic lupus erythematosus. Prevalence and relation to disease expression.
Significant fatigue was observed in 63/83 (76%) SLE patients. Patients with fatigue had significantly lower lymphocyte counts (1090 +/- 60 vs 1675 +/- 205 cells/mm3 P = 0.003), and higher ratings for headache, nervousness and musculoskeletal symptoms and signs. These disease parameters also correlate significantly with the magnitude of fatigue. Fatigue correlated with disease activity index (r = 0.49 P < 0.001).
Wysenbeek
A J
AJ
Rheumatology Unit, B. Beilinson Medical Center, Petah Tiqva, Israel.
Leibovici
L
L
Weinberger
A
A
Guedj
D
D
D000328:Adult; D005221:Fatigue / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013223:Statistics as Topic; D013997:Time Factors