title: [Changes in the chromatin structure under the influence of intranuclear bacteria with antihistone activity].
abstract: Computed TV morphodensitometry was used to examine the integration of bacteria into the human nuclear genome. The bacterial strains with antihistone activity were shown to be incorporated into the structure of chromatin structure of an epithelial cell with its network organization impaired. The microscopic analysis of cultured Hep 2 cells by manual scanning indicated that genetically active bacteria were incorporated into the nucleus and nucleolus.
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Sokolov
mesh_terms: D002467:Cell Nucleus / Q000382:microbiology* / Q000648:ultrastructure*; D002478:Cells, Cultured / Q000382:microbiology / Q000648:ultrastructure; D002843:Chromatin / Q000382:microbiology* / Q000648:ultrastructure*; D004848:Epithelium / Q000382:microbiology / Q000648:ultrastructure; D006657:Histones / Q000037:antagonists & inhibitors*; D006801:Humans; D008837:Micrococcus / Q000472:pathogenicity* / Q000648:ultrastructure; D009297:Nasal Mucosa / Q000382:microbiology / Q000648:ultrastructure
chemical_list: D002843:Chromatin; D006657:Histones
vernacular_title: Izmeneniia v strukture khromatina pod vliianiem vnutriiadernykh bakteriĭ s antigistonovoĭ aktivnost'iu.