title: Left ventricular volume calculation with integrated backscatter from echocardiography.
abstract: Integrated backscatter analysis (IB) is a new echocardiographic method for automatically differentiating tissue from blood on the basis of differences in the amplitude of reflected ultrasound. Left ventricular volume was estimated with IB by use of a modification of Pappus' theorem and a summated ellipsoid method. IB measurements correlated well with a standard biplane area-length method derived off-line from endocardial borders drawn by hand from the same echocardiographic data (y = 1.09 x - 35, r = 0.95). Integrated backscatter measurement of ventricular volume derived from six imaging planes with both the Pappus' rule and the summated ellipsoid methods correlated well with magnetic resonance imaging volume estimates (r = 0.91 and r = 0.90, respectively), whereas use of one imaging plane correlated less well (r = 0.75). Automated analysis of integrated backscatter differentiates tissue from blood sufficiently to allow accurate volume calculations compared with magnetic resonance imaging and to standard hand-drawn echo techniques. This method provides accurate measurement of left ventricular volumes that should be useful in clinical hemodynamic assessments.
authors.affiliation: Department of Cardiology, Cleveland Clinic Foundation, Ohio.
authors.forename: W J
authors.initials: WJ
authors.lastname: Stewart
authors.forename: S M
authors.initials: SM
authors.lastname: Rodkey
authors.forename: S
authors.initials: S
authors.lastname: Gunawardena
authors.forename: R D
authors.initials: RD
authors.lastname: White
authors.forename: B
authors.initials: B
authors.lastname: Luvisi
authors.forename: A L
authors.initials: AL
authors.lastname: Klein
authors.forename: E
authors.initials: E
authors.lastname: Salcedo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004452:Echocardiography / Q000379:methods*; D006331:Heart Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D008962:Models, Theoretical; D012815:Signal Processing, Computer-Assisted