title: Severe vascular toxicity associated with cisplatin-based chemotherapy.
abstract: A 19-year-old man with a germ cell tumor who experienced hypertension, acute myocardial infarction, and cerebrovascular accident (CVA) associated with hypomagnesemia as late complications of cisplatin-based chemotherapy is presented, and previously reported cases in the literature are reviewed. Different physiopathologic mechanisms are hypothesized for early and late vascular complications of cisplatin.
authors.affiliation: Department of Medicine, Ankara University, School of Medicine, Ibn-i Sina Hospital, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Içli
authors.forename: H
authors.initials: H
authors.lastname: Karaoğuz
authors.forename: D
authors.initials: D
authors.lastname: Dinçol
authors.forename: A
authors.initials: A
authors.lastname: Demirkazik
authors.forename: N
authors.initials: N
authors.lastname: Günel
authors.forename: R
authors.initials: R
authors.lastname: Karaoğuz
authors.forename: A
authors.initials: A
authors.lastname: Uner
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001157:Arterial Occlusive Diseases / Q000139:chemically induced*; D002561:Cerebrovascular Disorders / Q000139:chemically induced; D002945:Cisplatin / Q000009:adverse effects*; D004562:Electrocardiography; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D008274:Magnesium / Q000097:blood; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced; D013724:Teratoma / Q000188:drug therapy; D013736:Testicular Neoplasms / Q000188:drug therapy
chemical_list: D008274:Magnesium; D002945:Cisplatin