[Efficacy of and tolerance to buspirone hydrochloride in the treatment of psychosomatic symptoms in clinical cardiology].
OBJECTIVE
To evaluate the efficacy of buspirone hydrochloride in patients of the cardiologic clinic with generalized anxiety.


METHODS
Fifty out-patients with psychosomatic cardiovascular symptoms in cardiology were treated for six weeks with initial dose of 5mg of buspirone hydrochloride t.i.d.


RESULTS
The results obtained were good in 76% of the patients, fair in 18% and ineffective in 6% of the cases. Thirteen patients (26%) reported at least one adverse event, the side effects reported were: somnolence, headache, flatulence, tinnitus, nasal congestion and dry mouth. No interruption of the treatment was needed.


CONCLUSIONS
Buspirone hydrochloride is a valid alternative for treating pathological anxiety in patients in which the state of alertness and good psychomotor skills must be preserved.
Ramires
J A
JA
Instituto do Coração do Hospital das Clínicas, FMUSP.
Solimene
M C
MC
Serrano Júnior
C V
CV
Mansur
A de P
Ade P
Pileggi
F
F
D000328:Adult; D000553:Ambulatory Care; D001007:Anxiety / Q000188:drug therapy*; D002065:Buspirone / Q000008:administration & dosage / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D011602:Psychophysiologic Disorders / Q000188:drug therapy*; D016896:Treatment Outcome
D002065:Buspirone
Eficácia e tolerabilidade do cloridrato de buspirona no tratamento dos sintomas psicossomáticos na clínica cardiológica.