Trisomy 4 in acute nonlymphocytic leukemia: the first Brazilian case.
We report the first South American case of acute nonlymphocytic leukemia, French-American-British (FAB) subtype M1, [1] with trisomy 4 as the sole chromosome abnormality. The patient denied exposure to toxic or carcinogenic substances.
Ribeiro
E M
EM
Departamento de Genética, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba-Paraná, Brazil.
Cavalli
I J
IJ
Tokutake
A S
AS
Sperandio-Roxo
V M
VM
Malvezzi
M
M
Pasquini
R
R
D000328:Adult; D001938:Brazil; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D014314:Trisomy