Microvenular hemangioma.
We report five cases of microvenular hemangioma, a recently described benign vascular disorder. Clinically, they were acquired, slowly enlarging angiomatous lesions without distinctive features. Histologically, these tumors were characterized by a proliferation of small-sized, irregularly branched, blood vessels throughout the dermis embedded in a desmoplastic stroma. In many areas, the endothelial cells were surrounded by pericytes. The architectural pattern of microvenular hemangioma make its differentiation possible from other cutaneous benign vascular lesions, namely, capillary hemangioma, lobular capillary hemangioma, angioblastoma, and hemangiomas in polyneuropathy, organomegaly, endocrinology, M protein, skin changes (POEMS) syndrome. A close relationship among these vascular proliferations is suggested.
Aloi
F
F
Department of Dermatology, University of Turin, Italy.
Tomasini
C
C
Pippione
M
M
D000328:Adult; D005260:Female; D006391:Hemangioma / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology*