title: Clinical findings in patients with marker chromosomes identified by fluorescence in situ hybridization.
abstract: Twenty-seven patients carrying marker chromosomes were previously collected, characterized by cytogenetic techniques, and identified by stepwise fluorescence in situ hybridization (FISH) with alpha-satellite DNA probes. Clinical features of 22 patients are described here and compared to other patients with marker chromosomes similarly identified and reported in the literature.
authors.affiliation: Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis 46202-5251.
authors.forename: R
authors.initials: R
authors.lastname: Plattner
authors.forename: N A
authors.initials: NA
authors.lastname: Heerema
authors.forename: P N
authors.initials: PN
authors.lastname: Howard-Peebles
authors.forename: J H
authors.initials: JH
authors.lastname: Miles
authors.forename: S
authors.initials: S
authors.lastname: Soukup
authors.forename: C G
authors.initials: CG
authors.lastname: Palmer
mesh_terms: D000328:Adult; D002675:Child, Preschool; D002869:Chromosome Aberrations; D000013:Congenital Abnormalities / Q000235:genetics*; D015342:DNA Probes; D004276:DNA, Satellite; D005260:Female; D005819:Genetic Markers; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007223:Infant; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012303:Ring Chromosomes; D012306:Risk
chemical_list: D015342:DNA Probes; D004276:DNA, Satellite; D005819:Genetic Markers