Hematology and serum biochemistry of Japanese quail fed dietary tri-n-butyltin oxide during reproduction.
During a subchronic toxicity and reproduction study with tri-n-butyltin oxide (TBTO) concentrations of 0, 24, 60, and 150 mg/kg diet in Japanese quail, preliminary data on hematology and serum biochemistry were obtained. The absence of serious effects in blood parameters in both adult quail and developing chicks are discussed in view of the adverse effects of TBTO on reproduction.
Coenen
T M
TM
NOTOX Safety and Environmental Research BV., 's-Hertogenbosch, The Netherlands.
Enninga
I C
IC
Cave
D A
DA
van der Hoeven
J C
JC
D000284:Administration, Oral; D000375:Aging / Q000097:blood; D000818:Animals; D001769:Blood / Q000187:drug effects*; D003370:Coturnix; D004305:Dose-Response Relationship, Drug; D005260:Female; D005659:Fungicides, Industrial / Q000633:toxicity*; D008297:Male; D012098:Reproduction / Q000187:drug effects; D012737:Sex Factors; D014220:Trialkyltin Compounds / Q000633:toxicity*
D005659:Fungicides, Industrial; D014220:Trialkyltin Compounds; C005961:bis(tri-n-butyltin)oxide