title: [Cogan syndrome. Reversible perceptive hearing loss, non-syphilitic interstitial keratitis and aortic valve insufficiency].
abstract: Cogan's syndrome (CS) is a systemic disease of putative immunological origin. The syndrome comprises fluctuating and progressive sensorineural hearing loss and nonsyphilitic interstitial keratitis. Other manifestations are seen, aortic insufficiency in particular. A characteristic case of CS is described in which reversal of sensorineural hearing loss was achieved during oral corticosteroid therapy. In addition, aortic valve insufficiency was diagnosed, necessitating surgical valve replacement.
authors.affiliation: Svendborg Sygehus, øreafdelingen og medicinsk afdeling.
authors.forename: A
authors.initials: A
authors.lastname: Møller
authors.forename: P
authors.initials: P
authors.lastname: Junker
mesh_terms: D000368:Aged; D001022:Aortic Valve Insufficiency / Q000175:diagnosis* / Q000601:surgery; D001327:Autoimmune Diseases; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000188:drug therapy; D006350:Heart Valve Prosthesis; D006801:Humans; D007634:Keratitis / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D013577:Syndrome
chemical_list: D011239:Prednisolone
vernacular_title: Cogan's syndrom. Reversibel perceptiv hørenedsoettelse, non-syfilitisk interstitiel keratitis og aortaklapinsufficiens.