[Lung damage in amiodarone therapy].
Amiodarone pulmonary toxicity is the most serious side effect of amiodarone therapy. We describe a patient who died of this adverse effect. The clinical presentation is most often that of an indolent illness, with cough and/or fever. The diagnosis is made by careful exclusion of other causes of the observed illness and the finding of clinical, radiographic, physiologic, and pathologic abnormalities compatible with amiodarone toxicity. Examination prior to drug therapy, including lung function tests, is recommended for later controls. Of the therapeutic options, discontinuation of amiodarone is most frequent. However, for some patients with life-threatening ventricular arrhythmias this is the only effective therapy.
Andreassen
A K
AK
Medisinsk avdeling, Det Norske Radiumhospital, Oslo.
Dolva
O
O
Berner
A
A
D000368:Aged; D000638:Amiodarone / Q000506:poisoning*; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology; D011859:Radiography
D000638:Amiodarone
Lungeskade ved amiodaronterapi.