[The effect of new synthetic fragments of thymus hormones on the proliferative response of lymphocytes].
Influence of three new artificial fragments of beta-thymosines Phe-Asp-Lys-Ala, Glu-Lys-Phe-Asp-Lys and Thr-Leu-Pro-Thr on phytohemagglutinin-induced proliferative response of human lymphocytes was studied. These peptides studied either stimulated or inhibited incorporation of 3H-thymidine in cell cultures of human lymphocytes. Possible mechanisms of these effects of the peptides on lymphocyte proliferation are discussed.
Ivanova
V P
VP
Sorochinskaia
E I
EI
Lozhkina
T K
TK
D000595:Amino Acid Sequence; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D006801:Humans; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects*; D013951:Thymus Hormones / Q000737:chemistry*
D010446:Peptide Fragments; D013951:Thymus Hormones
Vliianie novykh sinteticheskikh fragmentov timusnykh gormonov na proliferativnyĭ otvet limfotsitov.