15N NMR studies of the binding of C15N- with gold(I) drugs.
15N NMR studies of the interaction of 15N cyanide ion with gold(I)-thiomalate (Autm) and gold(I)-thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two 15N ions containing species Au(C15N)2- and RS-Au-C15N- (where RS- = tm- or tg-) were identified at 265.94 and 260.30 ppm, respectively. From the broadened 15N NMR signals, approximate life times of the RS-Au-CN- species were calculated.
Isab
A A
AA
Chemistry Department, King Fahad University of Petroleum and Minerals, Dhahran, Saudi Arabia.
Ghazi
I H
IH
Wazeer
M I
MI
Perzanowski
H P
HP
D006051:Aurothioglucose; D002250:Carbon Radioisotopes; D003486:Cyanides; D006052:Gold Sodium Thiomalate; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009587:Nitrogen Isotopes
D002250:Carbon Radioisotopes; D003486:Cyanides; D009587:Nitrogen Isotopes; D006052:Gold Sodium Thiomalate; D006051:Aurothioglucose