title: Fetal outcome in mothers with impaired glucose tolerance in pregnancy.
abstract: A 75 g oral glucose tolerance test was carried out on 953 pregnant women who were identified on the basis of clinical risk factors. The tests were analysed by the WHO criteria: 826 were normal, 120 showed impaired glucose tolerance, and 7 identified diabetes. A number of obstetric and perinatal outcome measures were compared between the groups with normal and impaired glucose tolerance, and also with 135 women who had pre-existing Type 1 diabetes and delivered during the study period. There was no significant difference in the incidence of antenatal complications between mothers with normal and impaired glucose tolerance. There was a higher rate of induced labour (p < 0.05) and caesarean section (p < 0.01) in the impaired glucose tolerance group compared to the normal group, but no difference in fetal outcome or neonatal morbidity. All of these outcome measures were increased in the Type 1 diabetic pregnancies.
authors.affiliation: Royal Maternity Hospital, Belfast, UK.
authors.forename: R N
authors.initials: RN
authors.lastname: Roberts
authors.forename: J M
authors.initials: JM
authors.lastname: Moohan
authors.forename: R L
authors.initials: RL
authors.lastname: Foo
authors.forename: J M
authors.initials: JM
authors.lastname: Harley
authors.forename: A I
authors.initials: AI
authors.lastname: Traub
authors.forename: D R
authors.initials: DR
authors.lastname: Hadden
mesh_terms: D000328:Adult; D001724:Birth Weight; D001786:Blood Glucose / Q000378:metabolism*; D002585:Cesarean Section; D036861:Delivery, Obstetric; D016640:Diabetes, Gestational; D005260:Female; D005865:Gestational Age; D005951:Glucose Tolerance Test; D006801:Humans; D006943:Hyperglycemia; D007231:Infant, Newborn; D007751:Labor, Induced; D007743:Labor, Obstetric; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000453:epidemiology; D011256:Pregnancy Outcome; D012016:Reference Values
chemical_list: D001786:Blood Glucose