A case of cutaneous B-cell lymphoma with a storiform stromal reaction.
A case of cutaneous B-cell lymphoma is described. The patient was treated only by surgical excision of the skin tumors five times during a period of about two years from February of 1984 to October of 1986. After the last surgical excision, a continuous disease-free period was achieved. Biopsy samples showed dense lymphocytic infiltrations with discrete masses in the dermis and subcutis; one of them showed a storiform pattern. At the time, the infiltrating cells were composed of medium and large lymphoid cells and spindle-shaped cells. The medium and large lymphoid cells were positive for CD20, CD22 and HLA-DR and negative for CD3, CD4, CD5, CD8, CD43, and kappa and lambda light chain. The spindle-shaped cells were negative for CD20, CD43, kappa and lambda light chain, lysozyme, and S-100 protein.
Nagatani
T
T
Department of Dermatology, Yokohama City University, School of Medicine, Japan.
Miyazawa
M
M
Matsuzaki
T
T
Iemoto
G
G
Kim
S T
ST
Baba
N
N
Miyamoto
H
H
Nakajima
H
H
D000328:Adult; D000951:Antigens, Neoplasm / Q000032:analysis; D001940:Breast; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000276:immunology / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*
D000951:Antigens, Neoplasm