title: [Detection of human papillomavirus DNA and clinicopathological study of vulvar human papillomavirus infection].
abstract: We studied 217 vulvar HPV infection patients by clinically, pathologically, and virologically. From 90.6% of the cauliflower-like vulvar lesions and 29.7% of the papillomatous and finger-like lesions, we detected HPV 6/11 DNA by dot blotting hybridization. The patients in 90.0% of the cauliflower-like group and 9.8% of the papillomatous and finger-like group had a high risk factor to intercourse with different sex partners (P < 0.0001). The pathological characteristics, nature history, and response to treatment were different. According to clinical, pathological, and virological findings divided three types: vulvar HPV infection type 1 (or condylomata acuminata), vulvar HPV infection type 2, and vulvar HPV infection type 3.
authors.affiliation: Department of Obstetrics and Gynecology, First Clinical School of Medicine, Beijing Medical University.
authors.forename: S R
authors.initials: SR
authors.lastname: Fan
mesh_terms: D000328:Adult; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000382:microbiology* / Q000473:pathology; D014412:Tumor Virus Infections / Q000382:microbiology* / Q000473:pathology; D014847:Vulvitis / Q000382:microbiology* / Q000473:pathology
chemical_list: D004279:DNA, Viral