title: The PIR-International databases.
abstract: PIR-International is an association of macromolecular sequence data collection centers dedicated to fostering international cooperation as an essential element in the development of scientific databases. PIR-International is most noted for the Protein Sequence Database. This database originated in the early 1960's with the pioneering work of the late Margaret Dayhoff as a research tool for the study of protein evolution and intersequence relationships; it is maintained as a scientific resource, organized by biological concepts, using sequence homology as a guiding principle. PIR-International also maintains a number of other genomic, protein sequence, and sequence-related databases. The databases of PIR-International are made widely available. This paper briefly describes the architecture of the Protein Sequence Database, a number of other PIR-International databases, and mechanisms for providing access to and for distribution of these databases.
authors.affiliation: Protein Information Resource, National Biomedical Research Foundation, Georgetown University Medical Center.
authors.forename: W C
authors.initials: WC
authors.lastname: Barker
authors.forename: D G
authors.initials: DG
authors.lastname: George
authors.forename: H W
authors.initials: HW
authors.lastname: Mewes
authors.forename: F
authors.initials: F
authors.lastname: Pfeiffer
authors.forename: A
authors.initials: A
authors.lastname: Tsugita
mesh_terms: D000595:Amino Acid Sequence; D016251:CD-ROM; D016208:Databases, Factual / Q000592:standards; D004926:Escherichia coli / Q000235:genetics; D016247:Information Storage and Retrieval; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D017386:Sequence Homology, Amino Acid
chemical_list: D011506:Proteins