[Role of heat-shock proteins in recovery of cell proliferation following high temperature treatment of Drosophila melanogaster larvae].
The processes of the recovery of proliferation activity of nervous ganglion cells following heat-shock (37 degrees C, 30 min) were compared in two strains of Drosophila melanogaster (Canton S--the wild-type strain and 1(1)ts403--the mutant with the defect in the heat-shock protein system). The ts-mutant is characterized by the delay n reaching the maximum level in the HSP's synthesis and by more prolonged synthesis of these proteins after heat shock as compared with the wild-type strain. The block in cell proliferation after heat-shock is also more prolonged in the ts mutant's nervous ganglion in comparison with the wild-type strain. These results are n accordance with the hypothesis about the role of HSP's in cell proliferation.
Mamon
L A
LA
Kutskova
Iu A
IuA
D000818:Animals; D002455:Cell Division / Q000502:physiology; D002869:Chromosome Aberrations / Q000502:physiology; D004331:Drosophila melanogaster / Q000235:genetics* / Q000378:metabolism; D005724:Ganglia / Q000166:cytology; D006360:Heat-Shock Proteins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D006358:Hot Temperature; D007814:Larva / Q000502:physiology; D008677:Metaphase / Q000502:physiology; D009154:Mutation
D006360:Heat-Shock Proteins
Rol' belkov teplovogo shoka v vosstanovlenii kletochnoĭ proliferatsii posle vozdeĭstviia vysokoĭ temperaturoĭ na lichinok Drosophila melanogaster.