title: Three-dimensional OctreoScan111 SPECT of abdominal manifestation of neuroendocrine tumours.
abstract: In the present study we have investigated the three-dimensional (3D) reconstruction of OctreoScan111 SPECT (single photon emission tomography) images in 20 patients with neuroendocrine tumours. All patients had at least 2 tumour lesions as assessed from computerized tomography (CT) and SPECT. The 3D rendering was performed using a software, which produces images by implementing direct rendering from voxels without an intermediate surface data structure. The software has options for a free choice of thresholding and possibilities of clipping in coronal, transversal and sagittal planes. The results obtained showed that 3D reconstruction with volume rendering (3Dvr) gave a superior topographical localization of tumour uptakes when compared with SPECT. The 3Dvr technique was also combined with transversal clipping in rendered volumes (3Dvr+c). The major advantage with the 3Dvr+c technique was found to be an improved visualization of anatomical references as well as improved diagnostic information in a particular, selected, transversal slice, thus facilitating the identification and comparison of individual tumour lesions.
authors.affiliation: Department of Oncology, University Hospital, Uppsala, Sweden.
authors.forename: J E
authors.initials: JE
authors.lastname: Westlin
authors.forename: H
authors.initials: H
authors.lastname: Ahlström
authors.forename: J
authors.initials: J
authors.lastname: Ylä-Jääski
authors.forename: K
authors.initials: K
authors.lastname: Oberg
authors.forename: S
authors.initials: S
authors.lastname: Nilsson
mesh_terms: D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007205:Indium Radioisotopes; D007414:Intestinal Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D008297:Male; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D009490:Neurosecretory Systems / Q000000981:diagnostic imaging* / Q000378:metabolism; D015282:Octreotide / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D004369:Pentetic Acid / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D007205:Indium Radioisotopes; C071632:SDZ 215-811; D004369:Pentetic Acid; D015282:Octreotide