title: On the frequency and reproducibility of orthostatic blood pressure changes in healthy community-dwelling elderly during 60-degree head-up tilt.
abstract: The postural effects of 20 minutes of 60-degree head-up tilt on systolic, diastolic, and mean arterial blood pressures (BPs), heart rate, and rhythm were studied in 70 healthy, community-dwelling volunteer subjects of both sexes, divided into three age groups. Group A consisted of 30 subjects, with a mean age of 76 years (range 65 to 95 years); group B had 19 subjects, with a mean age of 54 years (range 45 to 64 years); and group C had 21 subjects, with a mean age of 33 years (range 24 to 44 years). To qualify, subjects had to have a systolic BP of 150 mm Hg or less and a diastolic BP of < 90 mm Hg, be taking no prescribed medications, have had no previous syncopal episodes, and have absence of any significant medical illness. Nine of 30 (30%) subjects in group A, 1 of 19 (5%) subjects in group B, and 2 of 21 (9.5%) subjects in group C exhibited asymptomatic postural drops in systolic blood pressure > 20 mm Hg (p < 0.05). The mean time for the systolic blood pressure drops in group A was 9.2 minutes. Results were reproducible upon retesting after 1 week.
authors.affiliation: Department of Medicine, Jersey City Medical Center, NJ 07304.
authors.forename: A
authors.initials: A
authors.lastname: Patel
authors.forename: A
authors.initials: A
authors.lastname: Maloney
authors.forename: A N
authors.initials: AN
authors.lastname: Damato
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D005260:Female; D006304:Health Status; D006339:Heart Rate; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis* / Q000503:physiopathology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011187:Posture / Q000502:physiology; D015203:Reproducibility of Results; D013575:Syncope / Q000175:diagnosis / Q000503:physiopathology