Surgical indication in children with congenital hemiparesis.
Nine children with perinatal occlusion of the middle cerebral artery, resulting in unilateral enlargement of one lateral cerebral ventricle associated with cortical atrophy and subcortical cavity formation, were operated on because of intractable epilepsy. All subjects exhibited mild to severe hemiparesis, localized in the right side of the body in six instances and in the left side in the three cases. All but one patient presented with some degree of psychomotor retardation. The surgical treatment consisted of the removal of the atrophic cerebral cortex. One child died after surgery because of disseminated intravascular coagulation. All the remaining eight children benefited from the operation, with a decrease in the hypertonia of the affected limbs and an improvement in dexterity and gait as well as in intellectual performance. Five patients could be considered seizure-free following the surgical treatment, and the remaining three experienced a significant reduction in the frequency of the seizures.
Di Rocco
C
C
Institute of Neurosurgery, Catholic University Medical School, Rome, Italy.
Caldarelli
M
M
Guzzetta
F
F
Torrioli
G
G
D001284:Atrophy; D001925:Brain Damage, Chronic / Q000151:congenital* / Q000601:surgery; D002540:Cerebral Cortex / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000151:congenital* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006429:Hemiplegia / Q000151:congenital* / Q000601:surgery; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed