[The effect of low and sublethal doses of ionizing radiation on the function of the spermatogenic epithelium and the yield of dominant lethal mutations in different strains of mice].
There was a 30% increase in spermatozoids with microheads and a 3-fold increase in "young" spermatozoids at later times after irradiation of BALB/c mice a dose of 1.0 Gy. With radiation doses of 0.1-1.0 Gy, BALB/c and CBA mice (which differ in viability of spermatogenous cells, the number of Sertoli cells and total embryonal death rate) exhibited a significant increase in the preimplantation death at the stage of spermatogonia and stem cells. The results obtained indicate reduction of the fertilizing capacity of sperm which is probably realized as dominant lethal mutations.
Mamina
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Sheĭko
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D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004848:Epithelium / Q000528:radiation effects; D005720:Gamma Rays; D005799:Genes, Dominant / Q000528:radiation effects*; D005804:Genes, Lethal / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D009154:Mutation; D011836:Radiation Tolerance; D013091:Spermatogenesis / Q000235:genetics / Q000528:radiation effects*; D013737:Testis / Q000528:radiation effects*; D013997:Time Factors; D014916:Whole-Body Irradiation
Vliianie malykh i subletal'nykh doz ioniziruiushchego izlucheniia na sostoianie spermatogennogo épiteliia i vykhod dominantnykh letal'nykh mutatsiĭ u mysheĭ raznykh liniĭ.