title: Giant cell lesions complicating fibro-osseous conditions of the jaws.
abstract: Three patients who presented with giant cell lesions complicating ossifying fibroma, Paget's disease, and cherubism are reported. The giant cell lesions complicating ossifying fibroma and cherubism were diagnosed as giant cell granuloma (GCG), whereas the lesion complicating Paget's disease demonstrated more aggressive clinical and histologic features. The possible therapeutic and prognostic implications of these findings are discussed.
authors.affiliation: Southampton General Hospital, UK.
authors.forename: C N
authors.initials: CN
authors.lastname: Penfold
authors.forename: P
authors.initials: P
authors.lastname: McCullagh
authors.forename: J W
authors.initials: JW
authors.lastname: Eveson
authors.forename: A
authors.initials: A
authors.lastname: Ramsay
mesh_terms: D000328:Adult; D002636:Cherubism / Q000150:complications* / Q000473:pathology; D005350:Fibroma / Q000150:complications* / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000150:complications* / Q000473:pathology; D008439:Maxillary Diseases / Q000150:complications* / Q000473:pathology; D008441:Maxillary Neoplasms / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D010001:Osteitis Deformans / Q000150:complications* / Q000473:pathology; D010016:Osteoma / Q000150:complications* / Q000473:pathology