Clinical findings in patients with marker chromosomes identified by fluorescence in situ hybridization.
Twenty-seven patients carrying marker chromosomes were previously collected, characterized by cytogenetic techniques, and identified by stepwise fluorescence in situ hybridization (FISH) with alpha-satellite DNA probes. Clinical features of 22 patients are described here and compared to other patients with marker chromosomes similarly identified and reported in the literature.
Plattner
R
R
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis 46202-5251.
Heerema
N A
NA
Howard-Peebles
P N
PN
Miles
J H
JH
Soukup
S
S
Palmer
C G
CG
D000328:Adult; D002675:Child, Preschool; D002869:Chromosome Aberrations; D000013:Congenital Abnormalities / Q000235:genetics*; D015342:DNA Probes; D004276:DNA, Satellite; D005260:Female; D005819:Genetic Markers; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007223:Infant; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012303:Ring Chromosomes; D012306:Risk
D015342:DNA Probes; D004276:DNA, Satellite; D005819:Genetic Markers