[Features of lipid peroxidation in the blood of patients with chronic glomerulonephritis at the stage of renal dysfunction in the presence of nephrotic syndrome].
An increase in the rate of lipid peroxidation and exhaustion of protective antioxidative factors were detected in blood of patients with chronic glomerulonephritis in renal failure. The severity of renal failure did not affect noticeably the alteration of the patterns studied, while the most serious impairments were found in patients with the nephrotic syndrome. The value of antioxidation coefficient whose calculation is given in the paper may be used as an integral pattern evaluating impartially the ratio between pro- and antioxidation factors. The drugs with antioxidative properties should be involved in routine courses of glomerulonephritis treatment especially in the nephrotic syndrome.
Tugusheva
F A
FA
Kulikova
A I
AI
Zubina
I M
IM
D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use; D002908:Chronic Disease; D005260:Female; D005921:Glomerulonephritis / Q000150:complications / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications*; D051437:Renal Insufficiency / Q000150:complications*
D000975:Antioxidants
Osobennosti perekisnogo okisleniia lipidov krovi bol'nykh khronicheskim glomerulonefritom v stadii narusheniia funktsii pochek na fone nefroticheskogo sindroma.