title: Solitary vaginal metastasis as a presenting form of unsuspected renal adenocarcinoma.
abstract: Vaginal bleeding may be the first clinical manifestation of an occult renal neoplasm. The renal adenocarcinoma is a tumor with a wide variety of presenting forms. Sometimes the clinical signs of the metastatic lesions are the first evidence of disease. The prevalence of solitary metastases at diagnosis is lower than 3%, and solitary vaginal metastasis from this tumor is rare. Histologically, this metastasis is indistinguishable from that of a primary vaginal mesonephric adenocarcinoma, making electron microscopy necessary for the differential diagnosis. Treatment consists of surgical removal of the renal neoplasm as well as the vaginal lesion.
authors.affiliation: Department of Obstetrics & Gynecology, Hospital Clínic i Provincial, University of Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Torné
authors.forename: J
authors.initials: J
authors.lastname: Pahisa
authors.forename: C
authors.initials: C
authors.lastname: Castelo-Branco
authors.forename: F
authors.initials: F
authors.lastname: Fábregues
authors.forename: C
authors.initials: C
authors.lastname: Mallofré
authors.forename: X
authors.initials: X
authors.lastname: Iglesias
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology* / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D009392:Nephrectomy; D014625:Vaginal Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery