Naltrexone and fluoxetine in Prader-Willi syndrome.
The case discussed is of a 9-year-old boy with a diagnosis of Prader-Willi, compulsive eating, severe skin picking, mild mental retardation, and behavioral problems. Prehospital, hospital, and posthospital course is reviewed. An approach using fluoxetine and naltrexone shows a marked improvement in weight control, skin picking, and behavior. Obesity and self-mutilation are discussed with regard to the use of fluoxetine and naltrexone.
Benjamin
E
E
Phoenix Children's Hospital.
Buot-Smith
T
T
D002648:Child; D002653:Child Behavior Disorders / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009271:Naltrexone / Q000627:therapeutic use*; D011218:Prader-Willi Syndrome / Q000188:drug therapy* / Q000523:psychology; D016728:Self-Injurious Behavior / Q000188:drug therapy* / Q000523:psychology
D005473:Fluoxetine; D009271:Naltrexone