title: [Efficacy of and tolerance to buspirone hydrochloride in the treatment of psychosomatic symptoms in clinical cardiology].
abstract: OBJECTIVE
  To evaluate the efficacy of buspirone hydrochloride in patients of the cardiologic clinic with generalized anxiety.
  
  
  METHODS
  Fifty out-patients with psychosomatic cardiovascular symptoms in cardiology were treated for six weeks with initial dose of 5mg of buspirone hydrochloride t.i.d.
  
  
  RESULTS
  The results obtained were good in 76% of the patients, fair in 18% and ineffective in 6% of the cases. Thirteen patients (26%) reported at least one adverse event, the side effects reported were: somnolence, headache, flatulence, tinnitus, nasal congestion and dry mouth. No interruption of the treatment was needed.
  
  
  CONCLUSIONS
  Buspirone hydrochloride is a valid alternative for treating pathological anxiety in patients in which the state of alertness and good psychomotor skills must be preserved.
authors.affiliation: Instituto do Coração do Hospital das Clínicas, FMUSP.
authors.forename: J A
authors.initials: JA
authors.lastname: Ramires
authors.forename: M C
authors.initials: MC
authors.lastname: Solimene
authors.forename: C V
authors.initials: CV
authors.lastname: Serrano Júnior
authors.forename: A de P
authors.initials: Ade P
authors.lastname: Mansur
authors.forename: F
authors.initials: F
authors.lastname: Pileggi
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D001007:Anxiety / Q000188:drug therapy*; D002065:Buspirone / Q000008:administration & dosage / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D011602:Psychophysiologic Disorders / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D002065:Buspirone
vernacular_title: Eficácia e tolerabilidade do cloridrato de buspirona no tratamento dos sintomas psicossomáticos na clínica cardiológica.