Electrolyte disturbance with omeprazole therapy.
Omeprazole is an antagonist to the H+K+ ATPase of the gastric parietal cell. We report a case of severe electrolyte disturbance in a 5-year-old child treated with omeprazole associated with excessive urinary sodium loss, that responded completely to omeprazole withdrawal.
Melville
C
C
Department of Paediatric Gastroenterology, Hospital for Sick Children, London, UK.
Shah
A
A
Matthew
D
D
Milla
P
P
D002675:Child, Preschool; D004942:Esophagitis, Peptic / Q000188:drug therapy; D006801:Humans; D007714:Klippel-Feil Syndrome / Q000150:complications; D008297:Male; D009853:Omeprazole / Q000009:adverse effects*; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced*
D012964:Sodium; D009853:Omeprazole; D011188:Potassium