Diagnostic use of B-cell alloantigen D8/17 in rheumatic chorea.
Two unrelated patients with a family history of rheumatic fever had isolated, acquired chorea. Both index cases, as well as affected family members, had increased expression of the rheumatic B-cell alloantigen D8/17. This test may help differentiate Sydenham chorea from lupus chorea.
Feldman
B M
BM
Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Zabriskie
J B
JB
Silverman
E D
ED
Laxer
R M
RM
D001402:B-Lymphocytes / Q000276:immunology*; D002648:Child; D002819:Chorea / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007519:Isoantigens; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis / Q000235:genetics; D008297:Male; D012213:Rheumatic Fever / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D013577:Syndrome
C082034:B-cell alloantigen D8-17; D007519:Isoantigens