title: [Local complications of papaverine-induced erection: follow-up at 7 years].
abstract: 127 patients whose age was from 36 to 68 years old, affected by coeundi impotence, have been started to pharmaco-injection. 44 of these patients practised self-injection for 3 years: 25% once a week, 60% fortnightly and 15% once a month. The 60% of first group patients showed a certain fibrotic plaque between the 11th and the 13th month. At the end of the first year two patients with significative penile deviation underwent to corporoplasty. The 40% (6 patients) that made injection every 15-20 days showed fibrotic plaque between the 22nd and the 32nd month. At the third year two more patients underwent to corporoplasty. The 9 patients that made pharmacoerection monthly, showed plaque after almost 38 months. Only 11 patients have been using self-injection from about 7 years. At the half of the fifth year all patients presented multiple plaques and the 95% showed significant bends. At the end of the sixth year, 3 patients with serious bend, not to permit sexual intercourses, underwent to corporoplasty, having refused prosthesis. The anatomo-pathologic situation of the cavernous bodies has showed an heavy fibrosis, hipertrophy of smooth muscle and many perivascular phlogistic infiltrates.
authors.affiliation: Clinica Urologica, Università di Genova.
authors.forename: A F
authors.initials: AF
authors.lastname: De Rose
authors.forename: G F
authors.initials: GF
authors.lastname: Oppezzi
authors.forename: S
authors.initials: S
authors.lastname: Scotto
mesh_terms: D000328:Adult; D000368:Aged; D007172:Erectile Dysfunction / Q000188:drug therapy; D005355:Fibrosis / Q000139:chemically induced; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000009:adverse effects* / Q000627:therapeutic use; D010413:Penis / Q000473:pathology*
chemical_list: D010208:Papaverine
vernacular_title: Complicanze locali della farmacoerezione con papaverina: follow-up a 7 anni.