Gynecologic surgery and adhesion prevention. Asherman's syndrome.
Asherman's Syndrome was described by Asherman in 1948 as Amenorrhea Traumatica. Since the introduction of hysteroscopic surgery about 1970, an enlarging experience with the repair as well as the induction of intrauterine adhesions has been collected. The pathology and histologic processes involved in surgical repair and induction of scar in the uterus are discussed. The influence of the hormonal milieu as well as the special nature of endometrial repair as observed from the histologic evolution of the endometrium in menstruation are thought to be important factors in the induction and correction of intrauterine scar. While probably a special case, the endometrial model for healing appears to be fundamentally the same as other tissues.
Neuwirth
R S
RS
College of Physicians and Surgeons of Columbia University, St. Luke's-Roosevelt Hospital Center, New York, NY 10025.
D000568:Amenorrhea / Q000209:etiology*; D003475:Curettage / Q000009:adverse effects*; D004598:Electrosurgery; D004717:Endometrium / Q000601:surgery; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008598:Menstruation / Q000502:physiology; D000267:Tissue Adhesions / Q000209:etiology* / Q000601:surgery; D014591:Uterine Diseases / Q000209:etiology* / Q000601:surgery; D014599:Uterus / Q000601:surgery*