title: Adenoma residua in colorectal cancer. A study of 34 colorectal cancers detected by an immunological occult blood test.
abstract: A retrospective histological study was made searching for adenoma remnants in 34 colorectal cancer specimens detected by the quantitative and human Hb-specific immunological FECA-EIA test for occult blood in the faeces. As a control group, 34 colorectal cancer preparations from routine hospital material were studied in a similar manner. A difference was found between these materials, 12 out of 34 study cancers showing adenoma residua compared with only two in the control group. Even if a proportion of colorectal cancers is apparently not associated with adenomas, it is suggested that the existence of adenoma remnants is a sign of biologically early tumour development and consequently, it might correlate with a favourable prognosis.
authors.affiliation: Department of Surgery, University Central Hospital, Turku, Finland.
authors.forename: I
authors.initials: I
authors.lastname: Häkkinen
authors.forename: O
authors.initials: O
authors.lastname: Järvi
authors.forename: E
authors.initials: E
authors.lastname: Nylamo
authors.forename: K O
authors.initials: KO
authors.lastname: Söderström
mesh_terms: D000368:Aged; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003111:Colonic Polyps / Q000473:pathology* / Q000601:surgery; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology / Q000601:surgery; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009780:Occult Blood