Benign course after massive ingestion of yohimbine.
Yohimbine is an alpha 2 adrenoreceptor antagonist occasionally used in the treatment of impotence. Overdose of this drug is uncommon. We describe a 62-year-old male who ingested 100, 2.0 mg tablets whose only adverse effects were tachycardia, hypertension, and anxiety of brief duration. The limited experience to date suggests a benign course even after massive overdose. Observation would seem to be the management of choice.
Friesen
K
K
Concordia General Hospital, Winnipeg, Manitoba.
Palatnick
W
W
Tenenbein
M
M
D001007:Anxiety / Q000139:chemically induced; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D062787:Drug Overdose; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D013610:Tachycardia / Q000139:chemically induced; D015016:Yohimbine / Q000009:adverse effects*
D015016:Yohimbine