Transient erythroblastopenia of childhood in Sweden: incidence and findings at the time of diagnosis.
All cases of transient erythroblastopenia in children less than 10 years of age, diagnosed in Sweden during the years 1987-89, were identified. Almost all (51/53) were less than 3 years of age. In this group, the incidence was 4.3/100 000, which is the same as that of acute lymphatic leukaemia. No geographical, but a possible temporal, cluster was seen in 1989. The anaemia was severe in some cases; haemoglobin concentration was less than 40 g/l in 8 of 53 children. Thrombocytosis and neutropenia were common and were attributed to high endogenous erythropoietin activity. Thirty-seven of 53 children were given a blood transfusion. All children recovered and no complications or relapses were seen. Transient erythroblastopenia of childhood is a benign disease, and it is important to make a correct diagnosis to prevent unnecessary anxiety for leukaemia or aplastic anaemia.
Skeppner
G
G
Department of Paediatrics, Orebro Medical Centre Hospital, Sweden.
Wranne
L
L
D000740:Anemia / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology; D002452:Cell Count; D002648:Child; D002675:Child, Preschool; D004920:Erythropoiesis; D005260:Female; D006402:Hematologic Diseases / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D012156:Reticulocytes; D012189:Retrospective Studies; D013548:Sweden / Q000453:epidemiology; D013922:Thrombocytosis / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology
D006454:Hemoglobins