title: Correlation of serum lipids, lipoproteins, lipid peroxide products and metals with coronary heart disease.
abstract: Serum lipids, lipoproteins, malondialdelyde (MDA) and metal levels were determined in 86 patients with coronary heart disease (CHD) proved angiographically and 33 controls subjects. Serum concentrations of TC, LDL-C, AI, MDA and Cu were significantly elevated and serum HDL-C, Zn and Mg contents were decreased markedly in patients. Correlation analyses indicated that the severity of coronary arterial lesions was related positively to serum TC, LDL-C, AI, MDA and Cu levels, and inversely to HDL-C levels; both the serum Cu and MDA contents were related positively to TC and LDL-C levels. These data suggest that serum Cu and MDA might have effects on the extent of CA lesions during the progress of atherosclerosis in patients with CHD.
authors.affiliation: Department of Cardiology, 1st Affiliated Hospital, 4th Military Medical University, Xi'an.
authors.forename: Y
authors.initials: Y
authors.lastname: Wen
authors.forename: X X
authors.initials: XX
authors.lastname: Qian
authors.forename: G L
authors.initials: GL
authors.lastname: Jia
authors.forename: S B
authors.initials: SB
authors.lastname: Gao
authors.forename: Y F
authors.initials: YF
authors.lastname: Jin
authors.forename: D Y
authors.initials: DY
authors.lastname: Han
authors.forename: S F
authors.initials: SF
authors.lastname: He
mesh_terms: D002784:Cholesterol / Q000097:blood*; D003327:Coronary Disease / Q000097:blood*; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D014131:Trace Elements / Q000097:blood*; D014280:Triglycerides / Q000097:blood
chemical_list: D008074:Lipoproteins; D014131:Trace Elements; D014280:Triglycerides; D008315:Malondialdehyde; D002784:Cholesterol