title: Management of chondrosarcoma including modular ceramic and alumina prosthetic replacement.
abstract: Forty-one cases of chondrosarcoma from varying sites throughout the body, and treated exclusively by one of the authors (R.L.H.) from 1972 to 1990 were reviewed. The symptoms, signs, location of tumours, treatment and progress are presented. Particular attention was paid to modular bone replacement techniques. Excision and reconstruction of the bone or joint were carried out in 17 femora, five tibia and six humeri. Comparison between this method of management and other techniques is discussed. Titanium and alumina prostheses for the hip, femur, tibia, shoulder and humerus have been designed by the senior author. These are both inert and modular, and have been found to be superior to other methods of treatment in both function and cosmesis. They do not possess the same potential donor infection risks and other disadvantages of allograft replacement. Immediate postoperative weight bearing and mobilization are possible with these systems. The Huckstep prostheses allow for bony ingrowth into their porous coated alumina sleeves, spacers and stems. In addition, the titanium alloy locking component for the femoral stems has an elasticity half that of other metal alloys and this was found to minimize stress shielding.
authors.affiliation: Department of Traumatic and Orthopaedic Surgery, University of New South Wales, Prince of Wales Hospital, Sydney, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Slater
authors.forename: R L
authors.initials: RL
authors.lastname: Huckstep
authors.forename: D
authors.initials: D
authors.lastname: Kirwan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000537:Aluminum Oxide / Q000627:therapeutic use; D001858:Bone Nails; D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation; D002516:Ceramics / Q000627:therapeutic use; D002813:Chondrosarcoma / Q000601:surgery*; D005260:Female; D005270:Femur Head / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D006811:Humerus / Q000601:surgery; D007719:Knee Joint / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants
chemical_list: D000537:Aluminum Oxide