title: Sequential imputation and multipoint linkage analysis.
abstract: A novel Monte Carlo method for linkage analyses involving large pedigrees and many polymorphic loci is introduced. Issues related to the efficiency of the method are discussed.
authors.affiliation: Department of Statistics, University of Chicago, IL 60637.
authors.forename: A
authors.initials: A
authors.lastname: Kong
authors.forename: N
authors.initials: N
authors.lastname: Cox
authors.forename: M
authors.initials: M
authors.lastname: Frigge
authors.forename: M
authors.initials: M
authors.lastname: Irwin
mesh_terms: D002874:Chromosome Mapping; D030342:Genetic Diseases, Inborn / Q000235:genetics; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D009010:Monte Carlo Method; D010375:Pedigree
chemical_list: D005819:Genetic Markers