[Experimental study on the action of EDTA-liposome to remove mercury from the mice given methylmercury chloride].
It was reported that experimental study on the action of EDTA-Liposome to remove mercury from the mice given methylmercury chloride showed that elimination of methylmercury chloride from brain, testicle, liver, kidney and blood of mice treated by EDTA-Liposome was more significant than that of mice treated by EDTA alone. Mercury level in feces of EDTA-Liposome treated group increased significantly (P < 0.001). The advantages of treatment with EDTA-Liposome were discussed. Applying EDTA-Liposome is an efficient method in therapy of metal poisoning.
Wang
K L
KL
Norman Bethune University of Medical Sciesces, Changchun.
Yang
H Y
HY
Li
Z C
ZC
D000818:Animals; D004337:Drug Carriers; D004492:Edetic Acid / Q000008:administration & dosage*; D005243:Feces / Q000737:chemistry; D008081:Liposomes; D008297:Male; D008628:Mercury / Q000032:analysis; D008767:Methylmercury Compounds / Q000506:poisoning*; D051379:Mice; D011041:Poisoning / Q000188:drug therapy
D004337:Drug Carriers; D008081:Liposomes; D008767:Methylmercury Compounds; D004492:Edetic Acid; D008628:Mercury; C004925:methylmercuric chloride