title: Response to a single oral test of molybdenum stable isotopes for absorption studies in humans.
abstract: Two volunteer subjects were given orally enriched solutions of Mo-95 and Mo-96 respectively. Blood samples were drawn at various times following the tracer administration. The Mo-95 and Mo-96 content in plasma samples was determined by proton nuclear activation and the response to the single oral test of enriched stable molybdenum isotopes was determined. Assuming a simple two-open-compartment model where the first compartment is the gastrointestinal tract and the other is the plasma, an indicative value of the fractional intestinal absorption for the two subjects is given. The feasibility of direct quantitative measurements of Mo intestinal absorption by the double-tracer technique, using stable tracers, is evidenced.
authors.affiliation: Dipartimento di Fisica dell'Universita' di Milano, Italy.
authors.forename: M C
authors.initials: MC
authors.lastname: Cantone
authors.forename: D
authors.initials: D
authors.lastname: de Bartolo
authors.forename: N
authors.initials: N
authors.lastname: Molho
authors.forename: L
authors.initials: L
authors.lastname: Pirola
authors.forename: G
authors.initials: G
authors.lastname: Gambarini
authors.forename: C
authors.initials: C
authors.lastname: Hansen
authors.forename: P
authors.initials: P
authors.lastname: Roth
authors.forename: E
authors.initials: E
authors.lastname: Werner
mesh_terms: D000284:Administration, Oral; D006801:Humans; D007408:Intestinal Absorption; D007554:Isotopes; D008982:Molybdenum / Q000008:administration & dosage* / Q000097:blood
chemical_list: D007554:Isotopes; D008982:Molybdenum