title: The SBASE protein domain library, release 2.0: a collection of annotated protein sequence segments.
abstract: SBASE 2.0 is the second release of SBASE, a collection of annotated protein domain sequences. SBASE entries represent various structural, functional, ligand-binding and topogenic segments of proteins [Pongor, S. et al. (1993) Prot. Eng., in press]. This release contains 34,518 entries provided with standardized names and it is cross-referenced to the major protein and nucleic acid databanks as well as to the PROSITE catalog of protein sequence patterns [Bairoch, A. (1992) Nucl. Acids Res., 20 suppl, 2013-2018]. SBASE can be used for establishing domain homologies using different database-search tools such as FASTA [Lipman and Pearson (1985) Science, 227, 1436-1441], FASTDB [Brutlag et al. (1990) Comp. Appl. Biosci., 6, 237-245] or BLAST3 [Altschul and Lipman (1990) Proc. Natl. Acad. Sci. USA, 87, 5509-5513] which is especially useful in the case of loosely defined domain types for which efficient consensus patterns can not be established. SBASE 2.0 and a set of search and retrieval tools are freely available on request to the authors or by anonymous 'ftp' file transfer from mean value of ftp.icgeb.trieste.it.
authors.affiliation: International Centre for Genetic Engineering and Biotechnology, Area Science Park, Trieste, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Pongor
authors.forename: V
authors.initials: V
authors.lastname: Skerl
authors.forename: M
authors.initials: M
authors.lastname: Cserzö
authors.forename: Z
authors.initials: Z
authors.lastname: Hátsági
authors.forename: G
authors.initials: G
authors.lastname: Simon
authors.forename: V
authors.initials: V
authors.lastname: Bevilacqua
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D016208:Databases, Factual; D006801:Humans; D008969:Molecular Sequence Data; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D012091:Repetitive Sequences, Nucleic Acid; D017386:Sequence Homology, Amino Acid; D012984:Software
chemical_list: D011506:Proteins