title: Myxedema coma. A form of decompensated hypothyroidism.
abstract: This article describes the major pathophysiologic alterations that occur in patients with long-standing hypothyroidism and how these alterations may predispose them to the development of a decompensated state, commonly referred to as myxedema coma. Early recognition and the employment of appropriate interventions serve as the cornerstone for successful management of this condition. The use and limitations of thyroid hormone therapy for treatment of this condition are emphasized.
authors.affiliation: University of Southern California School of Medicine, Los Angeles.
authors.forename: J T
authors.initials: JT
authors.lastname: Nicoloff
authors.forename: J S
authors.initials: JS
authors.lastname: LoPresti
mesh_terms: D000368:Aged; D003128:Coma / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009230:Myxedema / Q000150:complications / Q000175:diagnosis*