title: Angiotropic lymphoma of paranasal sinuses with initial symptoms of oculomotor nerve palsy.
abstract: A 78-year-old female was found to have angiotropic lymphoma, a rare fatal disease, with initial symptoms of oculomotor nerve palsy. A biopsy of the paranasal sinus mucosa showed that the small vessels were occupied by large mononuclear cells which upon immunohistochemical examination tested positive for pre B-cell markers. She felt a gradually increasing pain in her left thigh. Magnetic resonance imaging suggested the involvement of neoplastic cells in the left femoral bone marrow. Following chemotherapy treatment remission was achieved. Early diagnosis of angiotropic lymphoma appears very significant, as this disorder could be well controlled by systemic chemotherapy.
authors.affiliation: First Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, Fukuoka, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Wake
authors.forename: A
authors.initials: A
authors.lastname: Kakinuma
authors.forename: N
authors.initials: N
authors.lastname: Mori
authors.forename: K
authors.initials: K
authors.lastname: Nagata
authors.forename: J
authors.initials: J
authors.lastname: Tsukada
authors.forename: K
authors.initials: K
authors.lastname: Nakata
authors.forename: M
authors.initials: M
authors.lastname: Misago
authors.forename: S
authors.initials: S
authors.lastname: Oda
authors.forename: I
authors.initials: I
authors.lastname: Morimoto
authors.forename: S
authors.initials: S
authors.lastname: Eto
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006390:Hemangioendothelioma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D009297:Nasal Mucosa / Q000473:pathology; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis* / Q000209:etiology; D010255:Paranasal Sinus Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D011241:Prednisone / Q000008:administration & dosage; D012074:Remission Induction; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone