title: Surface modification of the biomedical polymer poly(ethylene terephthalate).
abstract: X-ray photoelectron spectroscopy was used to characterize modified surfaces of a biomedically important polymer, poly(ethylene terephthalate). Several modification schemes were investigated and direct silanization with 3-aminopropyltriethoxysilane was found to be the optimum procedure, resulting in an aminated surface. Surface coverage of up to 100% was achieved with retention of the polymeric structural integrity. Further activation of the silanized surface was accomplished with two cross-linkers, glutaraldehyde and sebacoyl chloride. A simple biomolecule, L-cysteine, was successfully immobilized onto a surface pre-treated with 3-aminopropyltriethoxysilane and glutaraldehyde, with a coverage of 42%.
authors.affiliation: Department of Chemistry, University of Toronto, Ontario, Canada.
authors.forename: L N
authors.initials: LN
authors.lastname: Bùi
authors.forename: M
authors.initials: M
authors.lastname: Thompson
authors.forename: N B
authors.initials: NB
authors.lastname: McKeown
authors.forename: A D
authors.initials: AD
authors.lastname: Romaschin
authors.forename: P G
authors.initials: PG
authors.lastname: Kalman
mesh_terms: D001672:Biocompatible Materials; D007202:Indicators and Reagents; D008855:Microscopy, Electron, Scanning; D011093:Polyethylene Terephthalates / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D007202:Indicators and Reagents; D011093:Polyethylene Terephthalates