title: The liver-spleen scan in systemic amyloidosis: a clue to the diagnosis.
abstract: The clinical findings in cirrhosis and systemic amyloidosis may be similar, leading to difficulties in diagnosis. We studied three patients with systemic amyloidosis with a 99mTc sulfur colloid liver-spleen scan. In all three patients, uptake by the spleen was less than the liver, in contrast with the increased splenic uptake seen in patients with cirrhosis. The liver-spleen scan may be a useful tool in differentiating patients with cirrhosis from those with systemic amyloidosis when clinical findings fail to give the proper diagnosis.
authors.affiliation: Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322.
authors.forename: R F
authors.initials: RF
authors.lastname: Straub
authors.forename: T D
authors.initials: TD
authors.lastname: Boyer
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013158:Splenic Diseases / Q000000981:diagnostic imaging*; D013671:Technetium Tc 99m Sulfur Colloid
chemical_list: D013671:Technetium Tc 99m Sulfur Colloid