Protective effect of vitamin E on brain ischaemia during ontogenesis.
Vitamin E in a dose of 150 mg and 300 mg/kg of body weight, administered i.p., has a protective effect--in the course of the whole ontogenesis--against stagnant hypoxia induced in the laboratory rat by positive radial acceleration + 10xg. The favourable influence of vitamin E is relatively greater in older animals.
Trojan
S
S
Institute of Physiology, First Faculty of Medicine, Charles University, Prague.
D000375:Aging; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002545:Brain Ischemia / Q000517:prevention & control*; D002540:Cerebral Cortex / Q000187:drug effects / Q000254:growth & development; D010100:Oxygen / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D014810:Vitamin E / Q000008:administration & dosage / Q000494:pharmacology*
D014810:Vitamin E; D010100:Oxygen