Cholestatic hepatitis associated with amoxicillin-clavulanate.
This 70-year-old man experienced an episode of cholestatic hepatitis most likely due to an immunologically mediated reaction to amoxicillin-clavulanate. The episode occurred after cessation of the drug combination. Duration of illness was 16 weeks, and the patient recovered completely.
Belknap
M K
MK
McClelland
K J
KJ
D000368:Aged; D000658:Amoxicillin / Q000009:adverse effects* / Q000627:therapeutic use; D019980:Amoxicillin-Potassium Clavulanate Combination; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced*; D002969:Clavulanic Acids / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D012852:Sinusitis / Q000188:drug therapy*
D002969:Clavulanic Acids; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin