title: [Current aspects of burn treatment].
abstract: Burn treatment is a complex therapeutic regimen, enclosing immediate resuscitation, burn would care and the complete spectrum of surgical intensive care as well as plastic surgical reconstruction. The pathophysiology of a severe burn injury resembles a maximal trauma response by activating a wide variety of mediators, resulting in a generalized tissue edema (capillary leak). Most important are sufficient fluid resuscitation and primary care, correct referral to a burn center, early enteral feeding and a consequent operative tactic with early removal of necrotic tissue and stable wound coverage. Sepsis is still the major mortality factor (75%). Besides established methods like skin culturing, future efforts are directed towards the generation of composite skin grafts and an immunological approach to influence or prevent the course of a burn sepsis.
authors.affiliation: Abteilung für Verbrennungen, Plastische und Handchirurgie, Berufsgenossenschaftlichen Unfallklinik Ludwigshafen.
authors.forename: G
authors.initials: G
authors.lastname: Germann
authors.forename: H U
authors.initials: HU
authors.lastname: Steinau
mesh_terms: D002053:Burn Units; D002056:Burns / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D003131:Combined Modality Therapy; D003422:Critical Care / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D011183:Postoperative Complications / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D013518:Surgery, Plastic / Q000379:methods; D015996:Survival Rate
vernacular_title: Aktuelle Aspekte der Verbrennungsbehandlung.