title: Erdheim-Chester disease with epiphyseal and systemic disease.
abstract: A case of Erdheim-Chester disease which affected the epiphysis and showed evidence of systemic disease is presented. Clinical and histopathological similarities with other forms of disseminated Langerhans' cell histiocytosis are noted, particularly reaction of infiltrating histiocytes for S100 and HLA-DR.
authors.affiliation: Department of Pathology, Nuffield Orthopaedic Centre, Oxford.
authors.forename: N A
authors.initials: NA
authors.lastname: Athanasou
authors.forename: C
authors.initials: C
authors.lastname: Barbatis
mesh_terms: D000368:Aged; D004838:Epiphyses / Q000473:pathology; D005487:Foam Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D008297:Male; D010026:Osteosclerosis / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging