title: [Cytostructure of the mantle zone in lymphatic tissue].
abstract: Four cellular layers of the follicular mantle zone in palatine tonsil lymphatic tissue were studied by electron microscopy after simultaneous immunophenotypical investigation. The first layer of the mantle zone consisting of small blastic cells was analogous to the small (centrocytoid) blastic layer of germinal centres. The second B monocytoid layer was lacking analogy in basic series of lymphocytes and seemed to be an independent morphological and probably functional unit. Plasmacytoid and clarocellular elements in outer layers of follicular mantle zone were in a way similar to T plasmacytoid and clarocellular components of Sézary syndrome infiltrates but considering transitional forms they had a local origin from incompletely transformed elements of B monocytoid layer. Inner follicular mantle zone was discussed as a source of incompletely transformed B lymphocytes for further mantle layers where their immunophenotypical modulation is taking place according to actual need. Outer mantle layers are aggressive against damaged epithelial and litoral structures and may be instrumental in a common reaction of B and T components.
authors.affiliation: Hlavův I. patologicko-anatomický ústav 1. LF UK, Praha.
authors.forename: B
authors.initials: B
authors.lastname: Bednár
mesh_terms: D006801:Humans; D014066:Palatine Tonsil / Q000166:cytology*
vernacular_title: Cytostruktura plást'ové zóny lymfatické tkánĕ.