Surface modification of the biomedical polymer poly(ethylene terephthalate).
X-ray photoelectron spectroscopy was used to characterize modified surfaces of a biomedically important polymer, poly(ethylene terephthalate). Several modification schemes were investigated and direct silanization with 3-aminopropyltriethoxysilane was found to be the optimum procedure, resulting in an aminated surface. Surface coverage of up to 100% was achieved with retention of the polymeric structural integrity. Further activation of the silanized surface was accomplished with two cross-linkers, glutaraldehyde and sebacoyl chloride. A simple biomolecule, L-cysteine, was successfully immobilized onto a surface pre-treated with 3-aminopropyltriethoxysilane and glutaraldehyde, with a coverage of 42%.
Bùi
L N
LN
Department of Chemistry, University of Toronto, Ontario, Canada.
Thompson
M
M
McKeown
N B
NB
Romaschin
A D
AD
Kalman
P G
PG
D001672:Biocompatible Materials; D007202:Indicators and Reagents; D008855:Microscopy, Electron, Scanning; D011093:Polyethylene Terephthalates / Q000737:chemistry*; D013499:Surface Properties
D001672:Biocompatible Materials; D007202:Indicators and Reagents; D011093:Polyethylene Terephthalates