Riboflavin can protect tissue from oxidative injury.
Elevated riboflavin levels have been reported to provide protection against oxidative damage caused by oxidized forms of hemeproteins. This effect of riboflavin may be mediated by an NADPH-dependent methemoglobin reductase.
Christensen
H N
HN
Department of Pediatrics, University of California, San Diego, La Jolla 92037.
D000818:Animals; D042966:Cytochrome-B(5) Reductase / Q000378:metabolism; D006420:Hemeproteins / Q000378:metabolism; D006801:Humans; D008168:Lung / Q000473:pathology; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control; D010084:Oxidation-Reduction / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D015427:Reperfusion Injury / Q000517:prevention & control*; D012256:Riboflavin / Q000494:pharmacology*
D006420:Hemeproteins; D042966:Cytochrome-B(5) Reductase; D012256:Riboflavin