The design and development of an immunosuppressive drug, mycophenolate mofetil.
Allison
A C
AC
Institute of Immunology and Biological Sciences, Syntex Research, Palo Alto, CA.
Eugui
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EM
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D002240:Carbohydrate Sequence; D002648:Child; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D004357:Drug Synergism; D006031:Glycosylation / Q000187:drug effects; D006084:Graft Rejection / Q000517:prevention & control; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D008969:Molecular Sequence Data; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D011687:Purines / Q000378:metabolism
D007166:Immunosuppressive Agents; D011687:Purines; D006160:Guanosine Triphosphate; D009173:Mycophenolic Acid