title: [A preliminary report on the treatment of climacteric symptoms with Org OD14].
abstract: Climacteric symptoms were treated with Org OD14 in 30 women. Each patient received 2.5 mg/day orally, for 90 consecutive days in 6 cases and 120 consecutive days in 24 cases. The results demonstrated a good clinical effect with a significant difference in Kupperman's score is 26.67 +/- 9.97 t 5.06 +/- 3.95 before and after treatment. The fasting urinary calcium/creatinine and urinary hydroxyproline/creatinine ratios, blood triglyceride and cholesterol levels decreased, vaginal cytology showed estrogenic effects during therapy. In 2 of 20 patients the endometrium changed from atrophic before treatment to slightly proliferative phase after treatment. The clinical use of org OD14 for perimenopaused women was discussed.
authors.affiliation: Beijing Hospital.
authors.forename: Y Y
authors.initials: YY
authors.lastname: Wu
mesh_terms: D000328:Adult; D045930:Anabolic Agents / Q000627:therapeutic use*; D002979:Climacteric / Q000187:drug effects*; D004717:Endometrium / Q000187:drug effects; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D009652:Norpregnenes / Q000627:therapeutic use*
chemical_list: D045930:Anabolic Agents; D009652:Norpregnenes; C027385:tibolone