title: [A female patient with Werner's syndrome].
abstract: We describe a 42-year old female with Werner's syndrome, an autosomal recessive connective tissue disorder, characterised, in her case, by juvenile cataract, chronic ulcers on the feet, characteristic skin changes, a typical appearance of the face ('bird-like face'), severe deformities of the feet, generalised osteoporosis, soft tissue calcifications and a high pitched hoarse voice. Werner's syndrome has to be distinguished from systemic sclerosis in particular. No causal therapy is available.
authors.affiliation: St. Antonius Ziekenhuis, afd. Reumatologie/Interne Geneeskunde, Nieuwegein.
authors.forename: E J
authors.initials: EJ
authors.lastname: ter Borg
authors.forename: J C
authors.initials: JC
authors.lastname: van der Horst
authors.forename: J W
authors.initials: JW
authors.lastname: Meijer
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011379:Prognosis; D011859:Radiography; D012595:Scleroderma, Systemic / Q000175:diagnosis; D012867:Skin / Q000473:pathology; D014898:Werner Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology
vernacular_title: Een patiënte met het syndroom van Werner.