title: Astins A and B, antitumor cyclic pentapeptides from Aster tataricus.
abstract: Two novel antitumor chlorine- and alloThr-containing cyclic pentapeptides, named astins A and B, both of which were isomers and took a cis configuration in one of the amide bonds, were isolated from Aster tataricus together with astin C. Their structures were solved by spectroscopic analysis and chemical degradation.
authors.affiliation: Tokyo College of Pharmacy, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Morita
authors.forename: S
authors.initials: S
authors.lastname: Nagashima
authors.forename: K
authors.initials: K
authors.lastname: Takeya
authors.forename: H
authors.initials: H
authors.lastname: Itokawa
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000494:pharmacology; D051379:Mice; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000494:pharmacology; D012510:Sarcoma 180 / Q000188:drug therapy
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010456:Peptides, Cyclic; C082413:astin A; C082414:astin B