Clinical correlates of acoustic neuroma morphology.
Thirty-eight patients with vestibular schwannomas were reviewed. A correlation was found between tumour morphology and clinical presentation. Based on our knowledge of the variability in the neurilemmal-neurologlial junction and therefore the site of origin of these tumours in relation to the internal auditory canal, a classification into three different appearances on magnetic resonance imaging was possible. Dumbbell shaped tumours (21 per cent) represented laterally arising schwannomas, lollipop shaped tumours (18 per cent) were medially arising and cone shaped tumours (61 per cent) were the more common intermediate form. Patients with laterally arising dumb-bell shaped tumours were more likely to present early with hearing loss and had smaller tumours than patients with medially arising lollipop shaped ones. The relatively well preserved hearing in patients with medially arising tumours made them more likely to present at a later stage with signs of trigeminal compression, cerebellar dysfunction and raised intracranial pressure.
Moffat
D A
DA
Department of Otoneurosurgery, Addenbrooke's Hospital, Cambridge.
Golledge
J
J
Baguley
D M
DM
Hardy
D G
DG
D003390:Cranial Nerve Neoplasms / Q000145:classification / Q000150:complications / Q000473:pathology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000145:classification / Q000150:complications / Q000473:pathology*; D014725:Vestibular Nerve / Q000473:pathology*