title: [Doppler ultrasound in high grade multiple pregnancies].
abstract: From 1987 until 1992, 16 triplets and 2 quadruplets were studied by pulsed Doppler ultrasound between 17 and 36 weeks of gestation. A resistance index (RI) of the foetal aorta and umbilical artery above the 95th percentile was considered pathological. Elevated RI-values of the umbilical artery as compared to the A. cerebri media were indicative of circulatory centralisation. Intrauterine growth retardation (IUGR) was found in 9 (16%) foetuses, discordant growth occurred in 7 (39%) pregnancies. 41 (73%) of 56 foetuses survived in good health. Four of 7 foetuses with pathological Doppler findings died. The three survivors were markedly retarded. Four of 6 cases of intrauterine endangered foetuses were detected by Doppler sonography. The diagnosis of IUGR or discordant growth was based more frequently on pathological Doppler findings than on biometry and improved upon by combinations of both methods. Doppler sonography proved to be an important complementary method in the monitoring of high-grade multiple pregnancies.
authors.affiliation: Univ.-Frauenklinik Freiburg.
authors.forename: H J
authors.initials: HJ
authors.lastname: Prömpeler
authors.forename: H
authors.initials: H
authors.lastname: Madjar
authors.forename: W
authors.initials: W
authors.lastname: Klosa
authors.forename: A
authors.initials: A
authors.lastname: du Bois
authors.forename: R
authors.initials: R
authors.lastname: Peukert
authors.forename: C
authors.initials: C
authors.lastname: Wilhelm
authors.forename: M
authors.initials: M
authors.lastname: Breckwoldt
mesh_terms: D000293:Adolescent; D000328:Adult; D001238:Asphyxia Neonatorum / Q000000981:diagnostic imaging; D001724:Birth Weight / Q000502:physiology; D002585:Cesarean Section; D005260:Female; D005307:Fertilization in Vitro; D005313:Fetal Death / Q000209:etiology; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D016216:Ultrasonography, Prenatal
vernacular_title: Dopplersonographie bei höhergradigen Mehrlingsschwangerschaften.