[Determination of six main components in compound theophylline tablet by convolution curve method after prior separation by column partition chromatography].
On a partition chromatographic column in which the support is Kieselguhr and the stationary phase is sulfuric acid solution (2 mol/L), three components of compound theophylline tablet were simultaneously eluted by chloroform and three other components were simultaneously eluted by ammonia-saturated chloroform. The two mixtures were determined by computer-aided convolution curve method separately. The corresponding average recovery and relative standard deviation of the six components were as follows: 101.6, 1.46% for caffeine; 99.7, 0.10% for phenacetin; 100.9, 1.31% for phenobarbitone; 100.2, 0.81% for theophylline; 99.9, 0.81% for theobromine and 100.8, 0.48% for aminopyrine.
Zhang
S Y
SY
First Military Medical University, Guangzhou.
Wang
G F
GF
Wu
Y T
YT
D000632:Aminopyrine / Q000032:analysis; D002845:Chromatography / Q000379:methods; D004338:Drug Combinations; D011786:Quality Control; D013607:Tablets; D013805:Theobromine / Q000032:analysis; D013806:Theophylline / Q000737:chemistry*
D004338:Drug Combinations; D013607:Tablets; D000632:Aminopyrine; D013806:Theophylline; D013805:Theobromine