title: [Detection of asbestos in thoracic lymph nodes in patients with asbestosis].
abstract: To detect a possible lymph transport of inhaled asbestos fibres and fragments from the human lung we examined via light and scanning electron microscope a total of 224 intrapulmonary, extrapulmonary and paratracheal lymph nodes of 6 postmortem cases and 3 lung resectates from patients with histologically proven pulmonary asbestosis. The lymph nodes were subdivided into 3 groups and examined separately. We found partly sharp-edged staff-shaped and partly amorphous dust particles that were mostly embedded in phagolysosomes of macrophages, using energy-dispersive x-ray microanalysis; these particles yielded a spectrum like that of asbestos, which means they must be identified as asbestos fragments. Besides these, typical asbestos bodies and asbestos needles were also identified.
authors.affiliation: Abteilung für Pathologie, Ruhr-Universität Bochum.
authors.forename: S
authors.initials: S
authors.lastname: Philippou
authors.forename: H
authors.initials: H
authors.lastname: Mandelartz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001194:Asbestos / Q000032:analysis*; D001195:Asbestosis / Q000473:pathology*; D004577:Electron Probe Microanalysis; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged
chemical_list: D001194:Asbestos
vernacular_title: Asbestnachweis in thorakalen Lymphknoten bei Patienten mit Asbestose.