title: Single-exposure dual-energy chest images with computed radiography. Evaluation with simulated pulmonary nodules.
abstract: OBJECTIVE
  Dual-energy subtraction radiography using computed radiography (CR) can aid in the detection of pulmonary abnormalities such as nodules, but the subtracted image requires higher x-ray exposure than usual to reduce quantum mottle. To reduce quantum mottle without increasing x-ray exposure, a new dual-energy subtraction algorithm was investigated that included an edge-adaptive smoothing process and a subtraction process. The signal-to-noise ratio and the image quality of this new subtracted image was significantly superior to that of conventional subtracted images.
  
  
  METHODS
  Observer performance of the subtracted digital radiography in detecting simulated pulmonary nodules was compared with original CR images and conventional subtracted digital radiography of 50 patients.
  
  
  RESULTS
  A combination of an original CR image and a new subtracted CR image was significantly superior to a single original CR image or a combination of an original CR image and a conventional subtracted CR image (P < .01).
  
  
  CONCLUSIONS
  The single-exposure dual-energy subtraction method is superior to the conventional subtraction method in the detection of pulmonary nodules.
authors.affiliation: Department of Radiology, Osaka University Medical School, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kido
authors.forename: J
authors.initials: J
authors.lastname: Ikezoe
authors.forename: H
authors.initials: H
authors.lastname: Naito
authors.forename: S
authors.initials: S
authors.lastname: Tamura
authors.forename: T
authors.initials: T
authors.lastname: Kozuka
authors.forename: W
authors.initials: W
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Shimura
authors.forename: H
authors.initials: H
authors.lastname: Kato
mesh_terms: D006801:Humans; D008961:Models, Structural; D011857:Radiographic Image Interpretation, Computer-Assisted; D015900:Radiography, Dual-Energy Scanned Projection; D013902:Radiography, Thoracic; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging*