title: [The antidepressive properties of anaprilin].
abstract: After chronic administration of propranolol (1 and 5 mg/kg) to rats for 14 days, the time course of forced swimming was changed, by decreasing the rhythmic index of depression. With propranolol, the depressogenic properties of reserpine and clonidine were attenuated. The antidepressive activity of propranolol was associated with cerebral beta-adrenoceptor block.
authors.forename: E B
authors.initials: EB
authors.lastname: Arushanian
authors.forename: E V
authors.initials: EV
authors.lastname: Beĭer
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003000:Clonidine; D003863:Depression / Q000188:drug therapy / Q000209:etiology; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004347:Drug Interactions; D008297:Male; D011433:Propranolol / Q000627:therapeutic use*; D051381:Rats; D012110:Reserpine; D013550:Swimming; D013997:Time Factors
chemical_list: D000928:Antidepressive Agents; D012110:Reserpine; D011433:Propranolol; D003000:Clonidine
vernacular_title: Antidepressivnye svoĭstva anaprilina.