[Efficacy of 2 different leukocyte filters for erythrocyte concentrates].
By leukocyte reduction in red blood cell concentrates to < 5 x 10(6) leukocytes per transfused unit, febrile non-hemolytic transfusion reaction as well as alloimmunization and transmission of certain viral diseases (CMV, HTLV-1) can be prevented. Using a Nageotte hemocytometer with a large-volume chamber, the residual leukocyte number after filtration of 40 buffy-coat free red blood cell units with the filters Pall RC100 and Sepacell R500 B1 was determined in a clinical routine setting. Both tested filters underscored the limit (< 5 x 10(6) leukocytes per unit) set by the American Association of Blood Banks. Hemoglobin loss accounted for 8.9 g (Pall RC100) versus 7.7 g (Sepacell R500 B1), which is about 15-18% of the hemoglobin content of a red blood cell concentrate.
Barth
A
A
Hämatologisches Zentrallabor der Universität Bern, Inselspital.
Passerini
M
M
Oppliger
R
R
Spycher
M
M
Nydegger
U
U
D001781:Blood Component Removal / Q000295:instrumentation*; D004906:Erythrocyte Count; D017707:Erythrocyte Transfusion; D005374:Filtration / Q000295:instrumentation*; D006400:Hematocrit; D006801:Humans; D007962:Leukocytes; D010976:Platelet Count; D012680:Sensitivity and Specificity
Wirksamkeit von zwei verschiedenen Leukozytenfiltern für Erythrozytenkonzentrate.