title: Sleep in nondepressed patients with panic disorder: II. Polysomnographic assessment of sleep architecture and sleep continuity.
abstract: This study assessed the EEG sleep of 16 patients with panic disorder who did not currently meet criteria for major depression in comparison to 16 age-comparable healthy controls. Patients with panic disorder had remarkably normal sleep, with only a modest reduction in total sleep time (374 +/- 46 min vs. 399 +/- 36 min) and delta sleep (11.4 +/- 6.2% vs. 16.4 +/- 6.6%) noted. Contrary to expectation, impairment in sleep maintenance and continuity was not found in the patients with panic disorder. We conclude (a) sleep in non-depressed patients with panic disorder is fairly unremarkable, and does not resemble that classically described for depressed patients, and (b) excessive arousability is not a characteristic feature of sleep in panic disorder.
authors.affiliation: Department of Psychiatry, University of Manitoba, Winnipeg, Canada.
authors.forename: M B
authors.initials: MB
authors.lastname: Stein
authors.forename: M W
authors.initials: MW
authors.lastname: Enns
authors.forename: M H
authors.initials: MH
authors.lastname: Kryger
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology*; D003866:Depressive Disorder / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D016584:Panic Disorder / Q000175:diagnosis / Q000503:physiopathology*; D017286:Polysomnography; D011930:Reaction Time / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology; D014851:Wakefulness / Q000502:physiology*