title: [Changes in the hemostatic system in anomalous uterine hemorrhages and uterine myoma at perimenopause].
abstract: Concentrations of some hemostasis system parameters in the total blood stream and in the menstrual fluid were measured in 58 patients of a perimenopausal age suffering from uterine bleedings and myomas. Plasminogen, fibrinogen, and fibrin/fibrinogen degradation product concentrations were increased in the menstrual fluid of patients with profuse uterine bleedings in comparison with patients with moderate menstrual discharge. These shifts were the most marked in the patients with submucous localization of uterine myoma. Gestrinon and danason exerted no pathologic effect on the studied hemostasis system parameters.
authors.forename: I G
authors.initials: IG
authors.lastname: Ishchenko
authors.forename: A L
authors.initials: AL
authors.lastname: Mishchenko
authors.forename: Iu D
authors.initials: IuD
authors.lastname: Landekhovskiĭ
authors.forename: L S
authors.initials: LS
authors.lastname: Ezhova
mesh_terms: D003613:Danazol / Q000627:therapeutic use; D005260:Female; D005867:Gestrinone / Q000627:therapeutic use; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D007889:Leiomyoma / Q000097:blood* / Q000188:drug therapy; D008593:Menopause / Q000097:blood* / Q000187:drug effects; D008875:Middle Aged; D013997:Time Factors; D014592:Uterine Hemorrhage / Q000097:blood* / Q000188:drug therapy; D014594:Uterine Neoplasms / Q000097:blood* / Q000188:drug therapy
chemical_list: D005867:Gestrinone; D003613:Danazol
vernacular_title: Izmeneniia v sisteme gemostaza pri anomal'nykh matochnykh krovotecheniiakh i miome matki v perimenopauzal'nom periode.