title: [Positron-emission tomographic study of the dopaminergic system in a case of secondary unilateral tremor after mesencephalic hematoma].
abstract: A 30 year-old woman developed a postural and rest tremor of the left hand following a right peduncular post-traumatic hematoma. Two years later, positron emission tomography showed a marked decrease in [18F] fluorodopa uptake contrasting with a normal [76Br] bromolisuride uptake in the right striatum. This suggests that: 1) chronic unilateral dopaminergic striatal denervation may occur without persistent D2 dopaminergic receptor upregulation in humans; and 2) symptomatic mesencephalic tremor may be, at least in part, related to dopaminergic striatal denervation.
authors.affiliation: Service Hospitalier Frédéric Joliot, DRIPP, CEA, Orsay.
authors.forename: A
authors.initials: A
authors.lastname: De Recondo
authors.forename: P
authors.initials: P
authors.lastname: Rondot
authors.forename: C
authors.initials: C
authors.lastname: Loc'h
authors.forename: C
authors.initials: C
authors.lastname: Crouzel
authors.forename: M H
authors.initials: MH
authors.lastname: Dao-Castellana
authors.forename: N G
authors.initials: NG
authors.lastname: Bathien
authors.forename: O
authors.initials: O
authors.lastname: Rascol
authors.forename: M
authors.initials: M
authors.lastname: Clanet
authors.forename: J
authors.initials: J
authors.lastname: De Recondo
authors.forename: Y
authors.initials: Y
authors.lastname: Samson
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications* / Q000175:diagnosis; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis; D003342:Corpus Striatum / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004298:Dopamine / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008636:Mesencephalon; D014055:Tomography, Emission-Computed; D014202:Tremor / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D004298:Dopamine
vernacular_title: Etude du système dopaminergique en tomographie par émission de positons dans un cas de tremblement unilatéral secondaire à un hématome mésencéphalique.