title: Visualization of nasopharyngeal carcinoma with Tl-201 chloride and a three-head rotating gamma camera SPECT system.
abstract: Tl-201 SPECT was performed on 12 patients with nasopharyngeal carcinoma (NPC) by means of a three-head rotating gamma camera to evaluate whether or not Tl-201 SPECT was useful and reliable for assessing the tumor viability of NPC. Tl-201 clearly accumulated in the tumor in 3 patients before radiation treatment and increased Tl-201 uptake by the lesion ceased after the treatment. Three of 9 patients who were followed up after radiotherapy developed apparent local recurrence and Tl-201 SPECT clearly visualized these recurrent lesions. Tl-201 SPECT was very useful for assessing the tumor response to irradiation and for detecting local recurrent tumor. A high resolution SPECT system employing Tl-201 chloride is a new reliable and accurate diagnostic tool for the assessment of NPC.
authors.affiliation: Division of Nuclear Medicine, Chiba Cancer Center Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Togawa
authors.forename: N
authors.initials: N
authors.lastname: Yui
authors.forename: F
authors.initials: F
authors.lastname: Kinoshita
authors.forename: F
authors.initials: F
authors.lastname: Shimada
authors.forename: K
authors.initials: K
authors.lastname: Omura
authors.forename: S
authors.initials: S
authors.lastname: Takemiya
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D015902:Gamma Cameras; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D010865:Pilot Projects; D013793:Thallium; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation*
chemical_list: D013794:Thallium Radioisotopes; C027549:thallium chloride; D013793:Thallium