title: [The 24-hour hemodynamic changes after percutaneous mitral valvuloplasty].
abstract: Hemodynamic studies were performed immediately before, within 1/2 hour and 24 hours after percutaneous mitral valvuloplasty in 31 patients with severe mitral stenosis and pulmonary hypertension. Single rubber-nylon balloon (Inoue balloon) technique was used in all the procedures. Mean transmitral gradient fell from 12.7 +/- 5.4 mmHg to 6.1 +/- 3.1 mmHg (p < 0.001). Mitral valve area increased from 0.9 +/- 0.2 cm2 to 1.8 +/- 0.3 cm2 (p < 0.001). Mean pressure in the left atrium decreased from 21.8 +/- 7.1 mmHg to 16.9 +/- 5.1 mmHg (p < 0.001). After 24 hours there was a significant further drop in left atrial pressure (or pulmonary capillary wedge pressure), that decreased to 11.5 +/- 5 mmHg (p < 0.001). Mean cardiac output increased from 4.1 +/- 0.8 l/min to 4.5 +/- 0.9 l/min immediately after successful valvuloplasty and after 24 hours was significantly higher (5.4 +/- 1.2 l/min; p < 0.001). Mean pulmonary pressure immediately decreased from 29.2 +/- 9.7 mmHg to 26.5 +/- 6 mmHg (p < 0.05) and after 24 hours was 19.4 +/- 6 mmHg (p < 0.001). Left ventricular end-diastolic pressure increased from 9.9 +/- 3.8 mmHg to 13.8 +/- 5 mmHg (p < 0.001). In conclusion, pulmonary hemodynamic and cardiac output improve immediately after percutaneous mitral valvuloplasty and get progressively better up to 24 hours from the procedure.
authors.affiliation: Istituto di Malattie dell'Apparato Cardiovascolare, Università degli Studi, Bologna.
authors.forename: G
authors.initials: G
authors.lastname: Piovaccari
authors.forename: A
authors.initials: A
authors.lastname: Marzocchi
authors.forename: F
authors.initials: F
authors.lastname: Prati
authors.forename: M
authors.initials: M
authors.lastname: Zimarino
authors.forename: C
authors.initials: C
authors.lastname: Marrozzini
authors.forename: M
authors.initials: M
authors.lastname: Ferlito
authors.forename: S
authors.initials: S
authors.lastname: Specchia
authors.forename: M
authors.initials: M
authors.lastname: Gobbi
authors.forename: A
authors.initials: A
authors.lastname: Branzi
authors.forename: B
authors.initials: B
authors.lastname: Magnani
mesh_terms: D000328:Adult; D002404:Catheterization; D002940:Circadian Rhythm / Q000502:physiology*; D004452:Echocardiography; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*
vernacular_title: Modificazioni emodinamiche 24 ore dopo valvuloplastica mitralica percutanea.