The discovery of erythropoietin.
A personal vignette of life as a resident and fellow at the Yale New Haven Hospital in the early 1950s follows. John Peters and his associates created a superb renal center at Yale New Haven, and they instilled in me a respect for quantitative measurements and a love for simple physiologic concepts. The environment was ideal for clinical and laboratory research, and it enabled me to show the existence of a regulatory erythropoietic hormone. I consider it a tribute to Dr. Peters that erythropoietin was later found to be produced by the kidneys and that it, as a recombinant drug, has helped ameliorate the anemia of uremia.
Erslev
A J
AJ
Cardeza Foundation for Hematologic Research, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
D000818:Animals; D003237:Connecticut; D004921:Erythropoietin / Q000266:history* / Q000494:pharmacology / Q000627:therapeutic use; D006400:Hematocrit; D049673:History, 20th Century; D006801:Humans; D011817:Rabbits; D012156:Reticulocytes / Q000187:drug effects
D004921:Erythropoietin