title: Laser tomography of heterogeneous scattering media using spatial and temporal resolution.
abstract: Time-resolved tomography is performed in transillumination by using 527 nm picosecond pulses from a passively mode-locked doubled Nd/glass laser and a streak camera to select photons according to their flight time. This work reports on the increase in contrast of a time-resolved profile of a 2 mm radius opaque object embedded in a scattering medium, constituted of diluted milk in a 30 mm thick cell. For spatial analysis, the emerging photons are detected through a 6 mm slit at the outlet face of the cell. Transmission profiles obtained as a function of time show that the contrast is enhanced for the shortest flight times, while the 'shadow' of the object is no longer detected after about 100 ps. Moreover, improvements in contrast are studied for different configurations of the model, to analyse separately the role of collimated and scattered photons. It is expected that such a tomographic method based on time-resolved absorption could be applied to imaging for more complex biological structures in the red and near-infra-red range.
authors.affiliation: INSERM Unité 2, Département de Physiologie, Faculté de Médecine, Créteil, France.
authors.forename: G
authors.initials: G
authors.lastname: Jarry
authors.forename: J P
authors.initials: JP
authors.lastname: Lefebvre
authors.forename: S
authors.initials: S
authors.lastname: Debray
authors.forename: J
authors.initials: J
authors.lastname: Perez
mesh_terms: D006801:Humans; D007834:Lasers; D008954:Models, Biological; D013997:Time Factors; D014054:Tomography / Q000379:methods*; D014172:Transillumination / Q000379:methods*