The stimulation by dendritic cells of host-versus-graft reactivity in vivo.
Dendritic cells (DC) isolated from peripheral intestinal lymph of inbred Wistar rats were injected into the hind footpads of Hooded CBH/Cbi rats. Administration of 10(4) and 5 x 10(5) allogeneic DC produced approximately six-fold increase in popliteal node weight. This is only marginally greater than that caused by similar doses of syngeneic DC and about 30% greater than that caused by allogeneic mononuclear cells. The data indicated that allogeneic DC were not effective stimulators of host-versus-graft reactions in this assay.
Chaudhuri
S
S
Department of Pathology, University College of Medicine, Calcutta, India.
Chaudhuri
S
S
Barfoot
R
R
Denham
S
S
Hall
J G
JG
D000818:Animals; D003713:Dendritic Cells / Q000276:immunology*; D006648:Histocompatibility; D006789:Host vs Graft Reaction / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D017737:Macrophages, Peritoneal / Q000276:immunology; D008285:Major Histocompatibility Complex; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar; D016038:Skin Transplantation / Q000276:immunology