Non-immune hydrops fetalis and bilateral pulmonary hypoplasia in a newborn infant with extralobar pulmonary sequestration.
Extralobar pulmonary sequestration was found in a newborn premature infant that presented with non-immune hydrops fetalis, massive bilateral hydrothorax and polyhydramnios in utero. The baby died of severe respiratory insufficiency 15 h after birth. Postmortem examination revealed distended lymphatic vessels in the sequestered lung tissue probably due to impeded lymph drainage. We suggest that not extralobar pulmonary sequestration itself but a subsequent massive unilateral hydrothorax due to severe obstruction of lymph drainage was the cause of the non-immune hydrops fetalis, pulmonary hypoplasia and polyhydramnios. If these symptoms are diagnosed before delivery, a search for extralobar pulmonary sequestration is indicated.
Brus
F
F
Department of Pediatrics, University Hospital Groningen, The Netherlands.
Nikkels
P G
PG
van Loon
A J
AJ
Okken
A
A
D000328:Adult; D001998:Bronchopulmonary Sequestration / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D015160:Hydrops Fetalis / Q000150:complications* / Q000000981:diagnostic imaging; D006876:Hydrothorax / Q000150:complications* / Q000151:congenital / Q000000981:diagnostic imaging; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis* / Q000473:pathology; D008168:Lung / Q000473:pathology; D006831:Polyhydramnios / Q000150:complications* / Q000000981:diagnostic imaging; D011247:Pregnancy; D016216:Ultrasonography, Prenatal