title: The management of carotid artery disease: application of new diagnostic techniques and their neuropathological significance.
abstract: The early management of patients with carotid artery disease was based on minimal investigative knowledge without much appreciation of its pathophysiological significance. During the last decade, however, the advent of non-invasive and functional imaging has increased our awareness and the significance of extracranial cervical vascular disease. This has led to more logical management strategies particularly for patients with carotid artery disease. Non-invasive imaging, in particular, has identified patients at risk and led to the establishment of large randomized trials of medical and surgical treatments, the recent results of which have altered management practice.
authors.affiliation: University Department of Neurology, University of Glasgow.
authors.forename: I
authors.initials: I
authors.lastname: Bone
authors.forename: A D
authors.initials: AD
authors.lastname: Mendelow
authors.forename: D I
authors.initials: DI
authors.lastname: Graham
mesh_terms: D002340:Carotid Artery Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D016893:Carotid Stenosis / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006801:Humans