title: Leiomyosarcoma of the bladder eighteen years after cyclophosphamide therapy for retinoblastoma.
abstract: We report a case of leiomyosarcoma in the bladder which occurred in an 18-year-old boy who had been treated with cyclophosphamide over a period of 6 years for retinoblastoma diagnosed 50 days postpartum. Total cystectomy and formation of an ileal conduit were performed. Three years after the operation, he was tumor-free.
authors.affiliation: Department of Urology, Mie University School of Medicine, Tsu, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Kawamura
authors.forename: M
authors.initials: M
authors.lastname: Sakurai
authors.forename: K
authors.initials: K
authors.lastname: Tsukamoto
authors.forename: H
authors.initials: H
authors.lastname: Tochigi
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use*; D015653:Cystectomy; D005134:Eye Neoplasms / Q000188:drug therapy*; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D008297:Male; D012175:Retinoblastoma / Q000188:drug therapy*; D013997:Time Factors; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy
chemical_list: D003520:Cyclophosphamide