title: Reinfection with hookworm after chemotherapy in Papua New Guinea.
abstract: Reinfection with hookworm (Necator americanus) following chemotherapy was studied over 2 years in a rural village in Madang Province, Papua New Guinea. The prevalence of hookworm infection had returned to pre-treatment levels after 2 years, and the geometric mean hookworm burden had returned to 58% of the pre-treatment value. The rate of acquisition of adult worms was independent of host age, and was estimated as a geometric mean of 2.9-3.3 worms/host/year (arithmetic mean 7.9-8.9 worms/host/year). There was significant predisposition to hookworm infection; the strength of this predisposition did not vary significantly between age or sex classes.
authors.affiliation: Department of Zoology, Oxford.
authors.forename: R J
authors.initials: RJ
authors.lastname: Quinnell
authors.forename: A F
authors.initials: AF
authors.lastname: Slater
authors.forename: P
authors.initials: P
authors.lastname: Tighe
authors.forename: E A
authors.initials: EA
authors.lastname: Walsh
authors.forename: A E
authors.initials: AE
authors.lastname: Keymer
authors.forename: D I
authors.initials: DI
authors.lastname: Pritchard
mesh_terms: D000367:Age Factors; D000818:Animals; D001196:Ascariasis / Q000150:complications; D015984:Causality; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D017221:Necator americanus; D009332:Necatoriasis / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D010219:Papua New Guinea / Q000453:epidemiology; D011716:Pyrantel Pamoate / Q000627:therapeutic use*; D012008:Recurrence; D012737:Sex Factors; D013997:Time Factors; D014257:Trichuriasis / Q000150:complications
chemical_list: D011716:Pyrantel Pamoate