title: Trisomy 4 in acute nonlymphocytic leukemia: the first Brazilian case.
abstract: We report the first South American case of acute nonlymphocytic leukemia, French-American-British (FAB) subtype M1, [1] with trisomy 4 as the sole chromosome abnormality. The patient denied exposure to toxic or carcinogenic substances.
authors.affiliation: Departamento de Genética, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba-Paraná, Brazil.
authors.forename: E M
authors.initials: EM
authors.lastname: Ribeiro
authors.forename: I J
authors.initials: IJ
authors.lastname: Cavalli
authors.forename: A S
authors.initials: AS
authors.lastname: Tokutake
authors.forename: V M
authors.initials: VM
authors.lastname: Sperandio-Roxo
authors.forename: M
authors.initials: M
authors.lastname: Malvezzi
authors.forename: R
authors.initials: R
authors.lastname: Pasquini
mesh_terms: D000328:Adult; D001938:Brazil; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D014314:Trisomy