title: Interstitial irradiation of a large, low grade ependymoma with stereotactically implanted iodine-125 seeds. Case report.
abstract: In this case report a patient with a large intraventricular benign ependymoma is presented. The tumour was treated with stereotactically implanted Iodine-125 seeds and interstitial irradiation. Extension (diameter: 6.5 cm) and volume (112.5 ml) of the lesion caused the application of an unusually low dose (tumour surface dose: 40 Gy). The tumour shrank significantly within a few weeks. Follow-up at nearly 5 years shows the patient to be tumour free.
authors.affiliation: Department of Stereotactic and Functional Neurosurgery, University Köln, Federal Republic of Germany.
authors.forename: J
authors.initials: J
authors.lastname: Voges
authors.forename: C
authors.initials: C
authors.lastname: Gaus
authors.forename: W
authors.initials: W
authors.lastname: Schlegel
authors.forename: O
authors.initials: O
authors.lastname: Pastyr
authors.forename: B
authors.initials: B
authors.lastname: Wowra
authors.forename: V
authors.initials: V
authors.lastname: Sturm
mesh_terms: D000328:Adult; D001918:Brachytherapy / Q000379:methods*; D002551:Cerebral Ventricle Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D004806:Ependymoma / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D011859:Radiography; D011879:Radiotherapy Dosage; D017287:Ventriculoperitoneal Shunt
chemical_list: D007457:Iodine Radioisotopes