title: Osteoradionecrosis of the petrous bone and recurrent cerebrospinal fluid otorrhoea.
abstract: A case is reported of delayed necrosis of the petrous bone following a course of radiotherapy for a well-differentiated squamous cell carcinoma in a 60-year-old female who presented with recurrent intractable cerebrospinal fluid otorrhoea, meningitis and pneumocephalus. Multiple attempts at surgical repair of the necrosed dural deficit and tegmental fistula failed and eventually petrousectomy was necessary leading to a successful outcome.
authors.affiliation: Royal Preston Hospital, Fulwood, UK.
authors.forename: R R
authors.initials: RR
authors.lastname: Sharma
authors.forename: A J
authors.initials: AJ
authors.lastname: Keogh
authors.forename: M
authors.initials: M
authors.lastname: Small
authors.forename: N E
authors.initials: NE
authors.lastname: New
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D002558:Cerebrospinal Fluid Otorrhea / Q000473:pathology / Q000601:surgery*; D004424:Ear Canal / Q000528:radiation effects*; D004428:Ear Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010025:Osteoradionecrosis / Q000473:pathology / Q000601:surgery*; D010579:Petrous Bone / Q000473:pathology / Q000528:radiation effects* / Q000601:surgery; D011183:Postoperative Complications / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D013524:Surgical Flaps / Q000379:methods