[Effect of fushen decoction on thyroid hormone in chronic glomerulonephritis of both spleen and kidney-yang deficiency patients].
Changes of thyroid hormone level before and after treatment in 45 patients with chronic glomerulo-nephritis were observed. Of which, 23 cases were treated with Fushen Decoction and the other with Shenyan Siwei tablet as control. The results showed: (1) The level of serum T3 and T4 of 45 patients were significantly reduced (P < 0.001-0.01). (2) The level of serum T3 and T4 were significantly negative correlated with the value of BUN and Scr and the score of both Spleen and Kidney-Yang Deficiency Syndrome (P < 0.01-0.05), but there existed no significant negative correlation with urinary protein excretion in 24 hours (P > 0.05). (3) After treatment with Fushen Decoction, the level of serum T3 and T4 significantly increased (P < 0.01-0.05), but no significant change was recorded in control group (P > 0.05). (4) Although the level of serum T3 and T4 were raised, they were still lower than those of normal people.
Han
M X
MX
Affiliated Hospital of Anhui College of TCM, Hefei.
Wang
Y P
YP
D000328:Adult; D000368:Aged; D001806:Blood Urea Nitrogen; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005921:Glomerulonephritis / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013963:Thyroid Hormones / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D016711:Yang Deficiency / Q000188:drug therapy*
D004365:Drugs, Chinese Herbal; D013963:Thyroid Hormones; D014284:Triiodothyronine; D013974:Thyroxine