title: Congenital nystagmus cosegregating with a balanced 7;15 translocation.
abstract: We report a family in which autosomal dominant congenital nystagmus cosegregates with a balanced 7;15 translocation. Ophthalmic investigation showed predominantly horizontal nystagmus with a small rotatory component and no significant loss of visual function. This finding suggests a possible localisation for autosomal dominant congenital nystagmus (McKusick 164100).
authors.affiliation: South West Thames Regional Genetic Service, St George's Hospital Medical School, London, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Patton
authors.forename: S
authors.initials: S
authors.lastname: Jeffery
authors.forename: N
authors.initials: N
authors.lastname: Lee
authors.forename: C
authors.initials: C
authors.lastname: Hogg
mesh_terms: D002884:Chromosomes, Human, Pair 15; D002897:Chromosomes, Human, Pair 7; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000151:congenital* / Q000235:genetics*; D010375:Pedigree; D014178:Translocation, Genetic