The human S-cone electroretinogram and its variation among subjects with and without L and M-cone function.
OBJECTIVE
To examine the S-cone ERG in subjects with and without L and M-cone function.


METHODS
Ganzfeld spectral flashes in the presence of strong Ganzfeld adapting fields are used to elicit S-cone ERGs.


RESULTS
The S-cone ERG b-wave ranges from 0.2 to 4 mV in amplitude and 38-45 msec in implicit time. There is a progressive decrease in amplitude with age. The response is similar in subjects with or without L and M cone function.


CONCLUSIONS
The S-cone ERG is detectable in subjects of all ages, but intersubject variability limits its diagnostic usefulness. The S-cone ERG is slightly later than but does not appear to be obviously influenced by the L and M-cone ERG.
Gouras
P
P
Edward S. Harkness Eye Institute, Columbia University, New York, New York.
MacKay
C J
CJ
Yamamoto
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001035:Aphakia / Q000503:physiopathology; D002648:Child; D003117:Color Vision Defects / Q000503:physiopathology*; D004596:Electroretinography; D006801:Humans; D008875:Middle Aged; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000502:physiology*