Primary splenic lymphoma with filiform ultrastructure.
A case of primary large cell splenic lymphoma of B lineage exhibiting filiform cell appearance is reported. The patient presented with massive splenomegaly, and following spontaneous splenic rupture, died of adult respiratory distress syndrome. The clinical aspects of the case, notably a lymphoma arising as a primary tumour in the spleen, with spontaneous spleen rupture and rapid fatal outcome, in combination with the filiform appearance of the lymphoma on electron microscopic examination, constitute an unusual combination of features. As far as is known, this B cell neoplasm is only the second primary splenic lymphoma of filiform type to be recorded.
Suresh
U R
UR
District Pathology Department, Stepping Hill Hospital, Stockport.
Eyden
B P
BP
Banerjee
S S
SS
Reeve
N L
NL
D000368:Aged; D006801:Humans; D007150:Immunohistochemistry; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D013160:Splenic Neoplasms / Q000473:pathology* / Q000648:ultrastructure