title: Correlation of corneal thickness with blood glucose control in diabetes mellitus.
abstract: The aim of this study was to prove the existence of a correlation between corneal thickness and glycaemic control in insulin-dependent patients. Ultrasound pachometry and blood glucose measurements were taken in 87 patients three times a day: fasting, two, and four hours after lunch. The sample was divided into three groups of patients: 30 of them did not have retinopathy, 30 presented background retinopathy and 27 proliferative retinopathy. Thirty normal age-matched subjects were the control group. No correlation was found between pachometry values, blood glucose and duration of diabetes in the three groups (p > 0.05). A significant increase in corneal thickness was found in patients with background and proliferative retinopathy compared to the others (p < 0.01). No corneal thickness differences resulted between background and proliferative retinopathy (p = 0.74).
authors.affiliation: Department of Ophthalmology, University of Milano, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Pierro
authors.forename: R
authors.initials: R
authors.lastname: Brancato
authors.forename: E
authors.initials: E
authors.lastname: Zaganelli
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003315:Cornea / Q000033:anatomy & histology / Q000473:pathology*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000517:prevention & control*; D003930:Diabetic Retinopathy / Q000097:blood / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis
chemical_list: D001786:Blood Glucose