title: Changes of subgingival microflora around single-crystal sapphire endosseous implants after experimental ligature-induced plaque accumulation in monkeys.
abstract: A study was performed to evaluate the change of subgingival microflora with plaque accumulation around the single-crystal sapphire implant. Four implants were inserted into mandibular and maxillary edentulous regions, and the super-structure was inserted 1 month after implant insertion in each of nine monkeys. Plaque control was maintained for 3 months after insertion to establish the baseline. Plaque was allowed to accumulate on one side by placement of ligatures around the implants and natural teeth with no plaque control. On the other side plaque control was continued for 9 months. Both the implants and natural teeth on the ligature side showed significant increases in proportions of motile rods and spirochetes. No significant difference of microflora was detected between the implants and natural teeth. These findings indicate that plaque control is necessary to maintain the normal microflora around the implant.
authors.affiliation: Department of Removable Prosthodontics, Hiroshima University School of Dentistry, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Akagawa
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: M
authors.initials: M
authors.lastname: Kawamura
authors.forename: H
authors.initials: H
authors.lastname: Tsuru
mesh_terms: D000537:Aluminum Oxide; D000818:Animals; D001419:Bacteria / Q000302:isolation & purification; D000044:Dental Abutments; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D003773:Dental Plaque / Q000382:microbiology*; D005260:Female; D005891:Gingivitis / Q000382:microbiology*; D008026:Ligation; D008251:Macaca; D013144:Spirochaetales / Q000302:isolation & purification
chemical_list: D015921:Dental Implants; D000537:Aluminum Oxide