title: Medulloblastomas.
abstract: 81 patients with biopsy proven medulloblastoma with a mean age of 11.4 years were reviewed. Total removal of the tumour was accomplished in 18 cases (22.2%), subtotal removal in 55 cases (67.9%) and biopsy alone in 8 cases (9.9%). 34 patients (27.5%) had a recurrence of the tumour and 8 patients underwent a second posterior fossa exploration at the time of recurrence. In patients with total resection, five-year survival was 27.7%. With partial resection, five-year survival decreased to 14.5%. In patients with radiotherapy chemotherapy, 21.4% survived 5 years after treatment but this rate decreased to 18.4% in patients treated with radiotherapy only. The surgical mortality rate was 12.3%.
authors.affiliation: Ankara University Faculty of Medicine, Department of Neurosurgery, Turkey.
authors.forename: H Z
authors.initials: HZ
authors.lastname: Gökalp
authors.forename: E
authors.initials: E
authors.lastname: Arasil
authors.forename: Y
authors.initials: Y
authors.lastname: Kanpolat
authors.forename: A
authors.initials: A
authors.lastname: Erdogan
authors.forename: H
authors.initials: H
authors.lastname: Deda
authors.forename: A
authors.initials: A
authors.lastname: Unlü
mesh_terms: D000293:Adolescent; D000328:Adult; D002528:Cerebellar Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D002648:Child; D002675:Child, Preschool; D016371:Cranial Irradiation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D015996:Survival Rate