Ovarian superstimulation and intrauterine insemination for the treatment of unexplained infertility.
OBJECTIVE
To evaluate the efficacy of controlled ovarian hyperstimulation (COH) and IUI in the treatment of unexplained infertility.


METHODS
The pregnancy rate (PR) in patients with unexplained infertility treated by COH and IUI (group A) was compared with a no-treatment control (group B).


METHODS
The Egyptian IVF-ET Center.


METHODS
Four hundred ninety-two patients with the diagnosis of unexplained infertility.


METHODS
Controlled ovarian hyperstimulation and IUI.


METHODS
Cycle fecundity per treatment cycle and PR per patient.


RESULTS
In group A cycle fecundity was 20.1% per treatment cycle, and the PR was 34.7% per patient. In group B the PR was 8.9% per patient. Pregnancy rate per patient was significantly higher in group A when compared with the spontaneous PR in group B.


CONCLUSIONS
Controlled ovarian hyperstimulation and IUI significantly increased the PR in patients with unexplained infertility when compared with a no-treatment control group.
Aboulghar
M A
MA
Egyptian IVF-ET Center, Cairo University, Egypt.
Mansour
R T
RT
Serour
G I
GI
Amin
Y
Y
Abbas
A M
AM
Salah
I M
IM
D000328:Adult; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D007315:Insemination, Artificial / Q000379:methods*; D016471:Ovarian Hyperstimulation Syndrome / Q000139:chemically induced; D010053:Ovary / Q000503:physiopathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D013268:Stimulation, Chemical; D014599:Uterus