title: Sturge-Weber syndrome: management of glaucoma with combined trabeculotomy-trabeculectomy.
abstract: We reviewed the records of 16 patients (19 eyes) with Sturge-Weber syndrome (SWS). Scleral pigmentation was present in 12 (63.2%) of these eyes; nevus of Ota in two (10.6%). Combined trabeculotomy-trabeculectomy was performed in 18 eyes. After a mean follow up of 42 months (range, 1 to 8 years), intraocular pressure was controlled (< or = 22 mm Hg) in 11 eyes (61.1%), and visual acuity was better than 6/60 in eight. Intraoperative hyphema occurred in four eyes (22.2%); vitreous loss in three (16.7%). Postoperative choroidal detachment occurred in three eyes (16.7%); vitreous hemorrhage in one (5.6%). In all of the cases of repeat surgery (three eyes), postoperative subconjunctival injections of 5-fluorouracil resulted in a diffuse filtering bleb. We conclude that combined trabeculotomy-trabeculectomy is a promising treatment for patients with SWS with glaucoma.
authors.affiliation: Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi.
authors.forename: H C
authors.initials: HC
authors.lastname: Agarwal
authors.forename: S
authors.initials: S
authors.lastname: Sandramouli
authors.forename: R
authors.initials: R
authors.lastname: Sihota
authors.forename: N N
authors.initials: NN
authors.lastname: Sood
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005500:Follow-Up Studies; D005901:Glaucoma / Q000150:complications / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007429:Intraocular Pressure; D008297:Male; D011379:Prognosis; D013341:Sturge-Weber Syndrome / Q000150:complications / Q000601:surgery*; D014130:Trabeculectomy / Q000009:adverse effects / Q000379:methods*; D014792:Visual Acuity
chemical_list: D005472:Fluorouracil