Metabolic pathway of homophthalic acid in Pseudomonas alcaligenes.
A microorganism capable of degrading homophthalic acid as a sole carbon source was isolated from garden soil. The strain was identified as Pseudomonas alcaligenes. The organism degraded homophthalate by a pathway which involved phenylacetate and p-hydroxyphenylacetate as intermediates. The intermediates have been identified by physico-chemical methods. A tentative pathway for the degradation of homophthalate is proposed based on isolation of intermediates, oxygen uptake studies and presence of enzymes involved in the degradation.
Karigar
C S
CS
Department of Chemistry, Karnatak University, Dharwad, India.
Pujar
B G
BG
D007535:Isomerases / Q000378:metabolism; D010795:Phthalic Acids / Q000378:metabolism*; D011549:Pseudomonas / Q000201:enzymology / Q000378:metabolism*; D012988:Soil Microbiology; D019745:cis-trans-Isomerases
D010795:Phthalic Acids; C060218:homophthalic acid; D007535:Isomerases; D019745:cis-trans-Isomerases; C021531:maleylacetoacetate isomerase