title: Epidermolysis bullosa acquisita: efficacy of high-dose intravenous immunoglobulins.
abstract: A 16-year-old boy had a 6-year history of a generalized bullous eruption that was resistant to multiple therapies. Findings of immunofluorescent split-skin studies and electron microscopy were consistent with a diagnosis of epidermolysis bullosa acquisita. Treatment with cyclosporine and prednisolone decreased new blister formation. Additional therapy with high-dose intravenous immunoglobulins was successful in controlling the patient's disease.
authors.affiliation: Department of Dermatology, Eberhard-Karls-Universität, Tübingen, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Meier
authors.forename: K
authors.initials: K
authors.lastname: Sönnichsen
authors.forename: G
authors.initials: G
authors.lastname: Schaumburg-Lever
authors.forename: R
authors.initials: R
authors.lastname: Dopfer
authors.forename: G
authors.initials: G
authors.lastname: Rassner
mesh_terms: D000293:Adolescent; D002908:Chronic Disease; D016572:Cyclosporine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D016107:Epidermolysis Bullosa Acquisita / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*
chemical_list: D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous; D016572:Cyclosporine; D011239:Prednisolone