Asymptomatic cerebral involvement in Sjögren's syndrome: MRI findings of 15 cases.
Fifteen patients with Sjögren's syndrome without clinical evidence of central nervous system disease were studied by MRI. Signal abnormalities were observed in 9 (60%). They were always visible on T2-weighted images as small punctate areas of high signal in the basal ganglia and the white matter of the cerebral hemispheres. Abnormalities were less frequently seen on T1-weighted images. Enlargement of cerebral sulci was observed in 6 cases. The specificity and significance of these abnormalities are discussed.
Pierot
L
L
Service de Neuroradiologie Charcot, G.H. Pitié-Salpêtrière, Paris, France.
Sauve
C
C
Leger
J M
JM
Martin
N
N
Koeger
A C
AC
Wechsler
B
B
Chiras
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001284:Atrophy; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012859:Sjogren's Syndrome / Q000175:diagnosis*