title: Influence of unilateral vocal fold fixation on the structure of the intrinsic laryngeal muscles.
abstract: Histomorphometric data (fiber frequencies, fiber diameters, and atrophy factors) were determined in laryngeal muscles [thyroarytenoid (VOC), posterior (PCA) and lateral (LCA) cricoarytenoids, and cricothyroid (CT) muscles]. Seventy-three muscles (43,700 fibers) from normal and carcinoma-infiltrated sides of the larynges of 11 patients were analyzed. The fiber diameters showed uniform values of 24.2 +/- 9.1 microns. Type-I fibers were more frequent in the PCA and less frequent in the LCA and the CT. In the VOC, the ratio was 1:1. The unilateral fixation of a vocal fold modified the structures of the LCA and the CT. The VOC and the PCA were not affected. A hypothesis based on the phonatory function of the CT is used to explain its atrophy.
authors.affiliation: Klinik für Hals-, Nasen- und Ohrenkranke, Universität München, FRG.
authors.forename: R
authors.initials: R
authors.lastname: Langkau
authors.forename: F
authors.initials: F
authors.lastname: Martin
authors.forename: F
authors.initials: F
authors.lastname: Klingholz
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000368:Aged; D006801:Humans; D007821:Laryngeal Muscles / Q000473:pathology*; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009133:Muscular Atrophy / Q000473:pathology; D014827:Vocal Cords / Q000473:pathology*
chemical_list: D000251:Adenosine Triphosphatases