Effects of xanthone glycoside on ephedrine-induced biting behavior and motor activity.
1-Hydroxy-3,4,7,8-tetramethoxyxanthone, beta-sitosterol, uvaol-3-palmitate, and sweroside have been isolated from the fresh whole plant of Tripterospermum lanceolatum (Hayata) Haraex Satake (Gentianaceae). Our results on the pharmacological studies of xanthone glycoside and lanceoside suggested that they have a CNS depressant effect.
Chen
I J
IJ
Department of Pharmacology, Kaohsiung Medical College, Taiwan.
Lin
C N
CN
Wu
B N
BN
Cheng
K L
KL
D000818:Animals; D001058:Apomorphine; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004809:Ephedrine; D006027:Glycosides / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013239:Stereotyped Behavior / Q000187:drug effects*; D014966:Xanthenes / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D044004:Xanthones
D006027:Glycosides; D014966:Xanthenes; D044004:Xanthones; C009689:xanthone; D004809:Ephedrine; D001058:Apomorphine