title: [Hemophiliac arthropathy of the knee joint. Gd-DTPA-enhanced MRI; clinical and roentgenological correlation].
abstract: 17 patients with hemophilic arthropathy of the knee joint were studied with static and dynamic MRT before and after i.v. bolus injection of Gadolinium-DTPA (0.1 mmol/kg body weight). After contrast enhancement, synovial proliferations exhibited an increase of signal intensity (SI) on FFE and SE images of 47.7% and 37.4% respectively, whereas muscle and fatty tissue, tendons, bone marrow and joint effusion revealed only minor increase in SI. The gradient of signal intensity (ratio SI/time) of pannus was 39.6%/min. Gd-DTPA enhanced MRI studies delineate and quantify the synovial proliferations in hemophilic arthropathy. Dynamic studies in hemophilic arthropathy do not provide qualitative assessment of the inflammatory process.
authors.affiliation: Radiologische Universitätsklinik, Bonn.
authors.forename: M
authors.initials: M
authors.lastname: Nägele
authors.forename: V
authors.initials: V
authors.lastname: Kunze
authors.forename: M
authors.initials: M
authors.lastname: Hamann
authors.forename: H
authors.initials: H
authors.lastname: Eickhoff
authors.forename: W
authors.initials: W
authors.lastname: Koch
authors.forename: J
authors.initials: J
authors.lastname: Oldenburg
authors.forename: M
authors.initials: M
authors.lastname: Reiser
authors.forename: A
authors.initials: A
authors.lastname: Steudel
mesh_terms: D000328:Adult; D003287:Contrast Media; D005682:Gadolinium; D019786:Gadolinium DTPA; D006395:Hemarthrosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D006467:Hemophilia A / Q000150:complications; D006801:Humans; D007719:Knee Joint / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D011859:Radiography; D013583:Synovial Membrane / Q000473:pathology
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
vernacular_title: Hämophile Arthropathie des Kniegelenkes. Gd-DTPA-verstärkte MRT; klinische und röntgenologische Korrelation.