Psychophysical visual function, retinopathy, and glycemic control in insulin-dependent diabetics with normal visual acuity.
We studied relations between psychophysical visual function and grade of retinopathy, glycemic control and clinical background data in 51 insulin-dependent diabetic patients, aged 17-47 years. Three separate qualities of visual function were examined, macular recovery time (nyctometry; 2 min adaptation), contrast sensitivity (Vistech 6000 chart; between 1.5 and 18 cycles per degree (cpd)) and colour vision (Fletcher DS8; protan/deutan and tritan). Only contrast sensitivity of 6 cpd was associated with the grade of retinopathy; reduced function was found in patients with retinopathy compared to those without. No correlations between macular recovery, contrast sensitivity and colour vision were found. None of the visual functions was significantly related to glycemic control, age, duration of diabetes, blood pressure, intraocular pressure, or urinary albumin excretion. Our data suggests that the neurosensory function of contrast sensitivity correlates more sensitively to the grade of diabetic retinopathy than macular recovery and colour vision. Cross-sectional assessments of different psychophysical visual functions seem to be of restricted clinical value as indicators of preceding glycemic control in diabetic patients with no or mild nonproliferative retinopathy.
Brinchmann-Hansen
O
O
Department of Ophthalmology, Trondheim University Hospital, Norway.
Bangstad
H J
HJ
Hultgren
S
S
Fletcher
R
R
Dahl-Jørgensen
K
K
Hanssen
K F
KF
Sandvik
L
L
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose; D003118:Color Perception / Q000502:physiology*; D015350:Contrast Sensitivity / Q000502:physiology*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology / Q000517:prevention & control*; D003930:Diabetic Retinopathy / Q000097:blood / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D010781:Photography; D011601:Psychophysics; D014792:Visual Acuity / Q000502:physiology*
D001786:Blood Glucose