title: A new method to study the efficiency of third generation blood filters.
abstract: In order to study the efficiency of third generation blood filters we have devised a new method using 3 microns pore size polycarbonate filter membranes and a filtration chamber to trap leucocytes passing through the blood filter. The method has enabled us to make two important observations: (1) The filters function very efficiently at the start but the efficiency diminishes progressively with time. (2) When the blood flow through the filter is retarded, due to defective priming and/or filter malfunction, the filters fail even at the outset of the transfusion.
authors.affiliation: Department of Haematology, Leicester Royal Infirmary.
authors.forename: M
authors.initials: M
authors.lastname: Sivakumaran
authors.forename: D R
authors.initials: DR
authors.lastname: Norfolk
authors.forename: K E
authors.initials: KE
authors.lastname: Major
authors.forename: J A
authors.initials: JA
authors.lastname: Revill
authors.forename: R M
authors.initials: RM
authors.lastname: Hutchinson
authors.forename: J K
authors.initials: JK
authors.lastname: Wood
mesh_terms: D004868:Equipment Failure; D006440:Hemofiltration; D006801:Humans; D007958:Leukocyte Count; D008851:Micropore Filters; D011076:Polycarboxylate Cement
chemical_list: D011076:Polycarboxylate Cement; C005506:polycarbonate