title: Laparoscopic correction of vesicoureteral reflux.
abstract: Major advances have been made in the area of laparoscopic surgery. The advantages of this approach include smaller incisions, shorter hospitalizations, a more rapid convalescence and decreased postoperative discomfort. To explore the technical feasibility of performing antireflux surgery laparoscopically, we conducted a pilot study in 4 mini-pigs in which bilateral vesicoureteral reflux had been created surgically. We applied a modification of the Lich extravesical ureteral approach to perform laparoscopic antireflux surgery. All mini-pigs underwent successful unilateral mobilization, creation of a bladder wall trough and creation of a new ureteral tunnel laparoscopically. Examinations were performed postoperatively, and then serially at 1, 2, 3 and 5 months after repair. Fluoroscopic cystograms demonstrated the resolution of reflux in the corrected ureters and persistence of reflux in the uncorrected control ureters in all animals. Excretory urography showed no evidence of obstruction. Laparoscopic correction of vesicoureteral reflux appears to be technically feasible in the animal model. Long-term followup is necessary to determine the possible applicability of this technique in humans.
authors.affiliation: Pediatric Urology Research Laboratory, Children's Hospital, Boston, Massachusetts.
authors.forename: A
authors.initials: A
authors.lastname: Atala
authors.forename: L R
authors.initials: LR
authors.lastname: Kavoussi
authors.forename: D S
authors.initials: DS
authors.lastname: Goldstein
authors.forename: A B
authors.initials: AB
authors.lastname: Retik
authors.forename: C A
authors.initials: CA
authors.lastname: Peters
mesh_terms: D000818:Animals; D010535:Laparoscopy; D008722:Methods; D011183:Postoperative Complications; D013552:Swine; D013556:Swine, Miniature; D014718:Vesico-Ureteral Reflux / Q000601:surgery*