title: [Effect of intraocular irrigating solution on electroretinogram during pars plana vitrectomy].
abstract: The effects of intraocular irrigating solutions on the human retina are not known. We recorded 30 Hz-flicker electroretinograms (ERGs) during vitrectomy, and examined the effects of perfusate S-MA2 and DE-057 on the human ERG. The amplitude of the 30 Hz-flicker ERGs were not significantly different for the two irrigating solutions. The peak latency of the 30 Hz-flicker ERG was increased 14 +/- 4.4% (mean +/- SE) during irrigation with S-MA2, compared with the preoperative peak latency. Replacement of S-MA2 by DE-057 increased the peak latency by 37 +/- 5.8% (p < 0.01). Since the peak latency of the 30 Hz-flicker ERG became shorter after replacement of DE-057 by S-MA2, these effects were reversible (p < 0.01).
authors.affiliation: Department of Ophthalmology, Miyazaki Medical College, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Maruiwa
authors.forename: S D
authors.initials: SD
authors.lastname: Kim
authors.forename: N
authors.initials: N
authors.lastname: Nao-i
authors.forename: A
authors.initials: A
authors.lastname: Sawada
mesh_terms: D000368:Aged; D001639:Bicarbonates / Q000494:pharmacology*; D004338:Drug Combinations; D004596:Electroretinography; D005260:Female; D005947:Glucose / Q000494:pharmacology*; D005978:Glutathione / Q000494:pharmacology*; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000494:pharmacology*; D012996:Solutions; D007507:Therapeutic Irrigation; D014821:Vitrectomy
chemical_list: D001639:Bicarbonates; D004338:Drug Combinations; D008903:Minerals; C030661:S-MA2 solution; D012996:Solutions; C013003:glutathione-bicarbonate-Ringer solution; D005978:Glutathione; D005947:Glucose