title: Monte Carlo analysis on a large pedigree.
abstract: Monte Carlo methods for linkage and segregation analysis are applied to the HGAR1 pedigree. To address these data, the methods are extended in several ways. The results are compared with those provided by PAP.
authors.affiliation: Department of Statistics, University of Washington, Seattle 98195.
authors.forename: E A
authors.initials: EA
authors.lastname: Thompson
authors.forename: S
authors.initials: S
authors.lastname: Lin
authors.forename: A B
authors.initials: AB
authors.lastname: Olshen
authors.forename: E M
authors.initials: EM
authors.lastname: Wijsman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D008040:Genetic Linkage; D020022:Genetic Predisposition to Disease; D006801:Humans; D006937:Hypercholesterolemia / Q000235:genetics; D007223:Infant; D007231:Infant, Newborn; D016013:Likelihood Functions; D008055:Lipids / Q000235:genetics; D008297:Male; D008875:Middle Aged; D008957:Models, Genetic; D009010:Monte Carlo Method; D010375:Pedigree; D011973:Receptors, LDL / Q000235:genetics
chemical_list: D008055:Lipids; D011973:Receptors, LDL