title: Primary low-grade B-cell lymphoma of the conjunctiva: a mucosa-associated lymphoid tissue type lymphoma.
abstract: We describe the clinical presentation, morphology, immunophenotypic features and molecular biology of seven cases of conjunctival lymphoid infiltration. In five cases there was either immunophenotypic or molecular evidence of B-cell lymphoma. Each of these cases showed the morphological, immunophenotypic and molecular feature of low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type. The findings suggest that most conjunctival lymphomas are of this type and explains their uniformly favourable prognosis.
authors.affiliation: Department of Histopathology, University College London Medical School, UK.
authors.forename: A C
authors.initials: AC
authors.lastname: Wotherspoon
authors.forename: T C
authors.initials: TC
authors.lastname: Diss
authors.forename: L X
authors.initials: LX
authors.lastname: Pan
authors.forename: C
authors.initials: C
authors.lastname: Schmid
authors.forename: M G
authors.initials: MG
authors.lastname: Kerr-Muir
authors.forename: S H
authors.initials: SH
authors.lastname: Lea
authors.forename: P G
authors.initials: PG
authors.lastname: Isaacson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003230:Conjunctival Neoplasms / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D004273:DNA, Neoplasm / Q000235:genetics; D005260:Female; D015326:Gene Rearrangement, B-Lymphocyte, Heavy Chain; D006801:Humans; D008221:Lymphoid Tissue / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000473:pathology; D011379:Prognosis
chemical_list: D004273:DNA, Neoplasm