Acute lymphoidic leukemia in a patient with thrombocytopenia/absent radii (Tar) syndrome.
OBJECTIVE
Patients with thrombocytopenia, absent radii (TAR) syndrome have a spontaneous amelioration of thrombocytopenia after infancy. No individual with the syndrome has been reported to develop subsequent bone marrow disease.


METHODS
We report a child with TAR syndrome who developed acute lymphoidic leukemia.


CONCLUSIONS
The TAR syndrome may predispose patients to other forms of marrow disease (as do other inherited marrow failure diseases). Additional cases are needed to confirm this hypothesis.
Camitta
B M
BM
Department of Pediatrics, Medical College of Wisconsin, Milwaukee.
Rock
A
A
D002675:Child, Preschool; D005260:Female; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D011884:Radius / Q000002:abnormalities*; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications* / Q000151:congenital