[Clinical and experimental study of left ventricular diastolic function in heart qi insufficiency syndrome].
In order to assess the left ventricular diastolic function of Heart Qi Insufficiency Syndrome (HQIS), apexcardiogram, ECG, electro-cardio-phonogram, impedance cardiogram were recorded and computerized simultaneously. A/D, PEP/LEVT, A/H were increased, while TRTI, DATI, HI, SV, CI reduced in 64 patients, 34 of them with coronary heart disease. The change was statistically significant. This study showed that DATI was more sensitive than PEP/LEVT in patients with HQIS, while there was no significant difference between abnormal ratio of them, overlapping of the two indices was showed. Replenishing Heart Mixture attained its therapeutic effect through improving abnormal left ventricular function. After treatment A/H, A/D, PEP/LEVT were reduced and DATI, SV, CI increased (P < 0.05-0.01). In experiment, HQIS was produced by acute myocardial ischemia in open-chest anesthetized dogs by left anterior descending coronary artery occlusion. It has been shown that dp/dtmax and T were more sensitive than dp/dtmax. Result of the clinical and the experimental study were consistent.
Cheng
W
W
Affiliated Hospital of Hubei College of TCM, Wuhan.
Shi
Z X
ZX
D000328:Adult; D000818:Animals; D003327:Coronary Disease / Q000188:drug therapy / Q000503:physiopathology*; D003971:Diastole; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D004452:Echocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D007702:Kinetocardiography; D008297:Male; D008875:Middle Aged; D005894:Panax; D010946:Plants, Medicinal; D016277:Ventricular Function, Left / Q000502:physiology*; D016711:Yang Deficiency / Q000188:drug therapy / Q000503:physiopathology*
D004365:Drugs, Chinese Herbal