title: Neurological state, infarct size and clinical outcome are related to early platelet count decrease in stroke.
abstract: We performed this study in order to verify the existence of a correlation between early platelet count reduction and initial neurological impairment, infarct extension and mortality or clinical outcome in an established ischemic cerebral infarction. The results demonstrate that the platelet consumption and/or accumulation in the infarct area, expressed by circulating platelet decrease, is related to the severity of neurological involvement, infarct size and poor clinical outcome.
authors.affiliation: II Clinica Medica, University of Rome La Sapienza, Italy.
authors.forename: E
authors.initials: E
authors.lastname: D'Erasmo
authors.forename: M
authors.initials: M
authors.lastname: Acca
authors.forename: D
authors.initials: D
authors.lastname: Pisani
authors.forename: M S
authors.initials: MS
authors.lastname: Volpe
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002544:Cerebral Infarction / Q000097:blood / Q000150:complications / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000097:blood* / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D009420:Nervous System / Q000503:physiopathology; D010976:Platelet Count; D011379:Prognosis; D013921:Thrombocytopenia / Q000097:blood* / Q000209:etiology* / Q000503:physiopathology