title: Development and application of a quantitative method of monitoring macroscopic cavitation in smooth surface carious lesions in vivo.
abstract: Replica techniques have been widely used in dental research, but not previously applied to the in vivo study of carious cavities on free smooth surfaces. A replica method was developed using an epimine resin as the impression material, and a silicone elastomer as the casting material. Cavity areas were measured on the replicas using the Reflex microscope. The sources of method error were identified and quantified. The method was successfully incorporated into a conventional clinical trial and changes in cavity size with time were investigated.
authors.affiliation: Department of Dental Surgery and Periodontology, University of Dundee, Scotland, UK.
authors.forename: A
authors.initials: A
authors.lastname: Neilson
authors.forename: N B
authors.initials: NB
authors.lastname: Pitts
mesh_terms: D000293:Adolescent; D001388:Aziridines; D003731:Dental Caries / Q000473:pathology* / Q000517:prevention & control; D003734:Dental Casting Investment; D003760:Dental Impression Materials; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D011108:Polymers; D011145:Polyvinyls; D016628:Replica Techniques / Q000295:instrumentation; D015203:Reproducibility of Results; D012117:Resins, Synthetic; D012833:Siloxanes; D014100:Toothpastes
chemical_list: D001388:Aziridines; D003734:Dental Casting Investment; D003760:Dental Impression Materials; D011108:Polymers; D011145:Polyvinyls; D012117:Resins, Synthetic; D012833:Siloxanes; D014100:Toothpastes; C034183:vinyl polysiloxane; C019085:scutan; D005459:Fluorides