[A case of binswanger-type dementia with bilateral temporoparietal hypoperfusion in SPECT].
We report a case of Binswanger-type dementia demonstrated bilateral temporoparietal hypoperfusion in SPECT with 123I-IMP. The perfusion pattern in the present case was different from those previously obtained in SPECT or PET studies of patients with Binswanger-type dementia, and was similar to regional abnormalities in patients with Alzheimer-type dementia. Temporoparietal hypoperfusion in this case is likely to be mediated by neuronal mechanisms via projection fibers as a result of the deep white matter lesions in the temporoparietal area. A decreased perfusion or metabolism in the temporoparietal area is considered to be a characteristic in patients with Alzheimer-type dementia, however, we should keep in mind that other cerebral disorders may also show a similar perfusion pattern.
Hanyu
H
H
Department of Internal Medicine, Tachikawa General Hospital.
Sugiyama
T
T
Abe
S
S
Kobayashi
Y
Y
Katsunuma
H
H
Asano
T
T
Arai
H
H
Takasaki
M
M
D000368:Aged; D000369:Aged, 80 and over; D000662:Amphetamines; D003704:Dementia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D010477:Perfusion; D012039:Regional Blood Flow; D013702:Temporal Lobe / Q000098:blood supply*; D015899:Tomography, Emission-Computed, Single-Photon
D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine