title: Antiplatelet therapy--Part I.
abstract: We summarize current information about aspirin and other antiplatelet drugs in patients with cardiac and vascular disease. For each indication, we briefly summarize the rationale for the use of antiplatelet therapy and describe the findings of relevant clinical trials. We propose recommendations for the use of these agents in clinical practice. Part I covers the use of antiplatelet therapy for the primary and secondary prevention of myocardial infarction, coronary thrombolysis, unstable and chronic stable angina, and coronary artery-saphenous vein bypass grafts. In part II we review the use of antiplatelet agents in coronary angioplasty, atrial fibrillation, artificial cardiac valves, stroke, and peripheral vascular disease.
authors.affiliation: Department of Pathology, Oregon Health Sciences University School of Medicine, Portland 97201-3098.
authors.forename: S H
authors.initials: SH
authors.lastname: Goodnight
authors.forename: B M
authors.initials: BM
authors.lastname: Coull
authors.forename: J H
authors.initials: JH
authors.lastname: McAnulty
authors.forename: L M
authors.initials: LM
authors.lastname: Taylor
mesh_terms: D000787:Angina Pectoris / Q000188:drug therapy; D000789:Angina, Unstable / Q000188:drug therapy; D001241:Aspirin / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000517:prevention & control; D001026:Coronary Artery Bypass; D003328:Coronary Thrombosis / Q000188:drug therapy; D006801:Humans; D009203:Myocardial Infarction / Q000517:prevention & control; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D015912:Thrombolytic Therapy
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin