[The display of hormesis in the action of quinoid radiotoxins].
Two hours before irradiation (7.5 Gy) mice were injected with quinoid radiotoxins in concentrations close to those formed in mouse blood after gamma-irradiation with a dose of 10 cGy. This increased the survival rate (from 10-20% to 80%), prevented the radiation-induced weight loss, and increased catalase activity in the liver and blood of exposed animals.
Kopylov
V A
VA
Revin
A F
AF
Kuzin
A M
AM
D000818:Animals; D002374:Catalase / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D002588:Cesium Radioisotopes; D004305:Dose-Response Relationship, Drug; D004307:Dose-Response Relationship, Radiation; D004353:Drug Evaluation, Preclinical; D005720:Gamma Rays; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000528:radiation effects; D008297:Male; D051379:Mice; D010636:Phenols / Q000528:radiation effects* / Q000627:therapeutic use; D010936:Plant Extracts / Q000528:radiation effects* / Q000627:therapeutic use; D011833:Radiation Injuries, Experimental / Q000201:enzymology / Q000401:mortality / Q000517:prevention & control*; D011836:Radiation Tolerance; D013997:Time Factors; D014118:Toxins, Biological / Q000528:radiation effects* / Q000627:therapeutic use
D002588:Cesium Radioisotopes; D010636:Phenols; D010936:Plant Extracts; D014118:Toxins, Biological; D002374:Catalase
Proiavlenie gormezisa v deĭstvii khinoidnykh radiotoksinov.