[The role of lipid peroxidation processes in the pathogenesis of paraneoplastic anemia].
Growth of Pliss lymphosarcoma inoculated into rats was accompanied by development of amenia, whereas content of Schiff bases was increased and concentration of SH-groups was decreased in erythrocytes of peripheric blood. Alterations in content of lipid peroxidation products, especially the decrease of SH-groups, were detected before manifestations of the anemia indications registered under laboratory conditions. This suggests the importance of lipid peroxidation in elevated rate of erythrocyte hemolysis during tumor growth.
Barmina
S E
SE
Novitskiĭ
V V
VV
Gol'dberg
E D
ED
D000740:Anemia / Q000150:complications / Q000378:metabolism*; D000818:Animals; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D015227:Lipid Peroxidation; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D009374:Neoplasms, Experimental / Q000150:complications*; D051381:Rats; D013438:Sulfhydryl Compounds / Q000378:metabolism
D013438:Sulfhydryl Compounds
Rol' protessov lipoperoksidatsii v patogeneze paraneoplasticheskoĭ anemii.