title: Fatal hyperthyroidism after amiodarone treatment and total lymphoid irradiation in a heart transplant recipient.
abstract: Recurrent severe allograft rejection is an uncommon but difficult management problem in heart transplantation. Total lymphoid irradiation is now a recognized treatment modality when conventional therapy has failed. We describe an unusual complication of total lymphoid irradiation in a patient who had been treated with amiodarone for malignant arrhythmias before transplantation.
authors.affiliation: Department of Cardiology, Mount Sinai Medical Center, Mount Sinai School of Medicine, New York, N.Y. 10029-6574.
authors.forename: P J
authors.initials: PJ
authors.lastname: Hauptman
authors.forename: B
authors.initials: B
authors.lastname: Fyfe
authors.forename: J
authors.initials: J
authors.lastname: Mechanick
authors.forename: S
authors.initials: S
authors.lastname: Lansman
authors.forename: A
authors.initials: A
authors.lastname: Gass
mesh_terms: D000638:Amiodarone / Q000009:adverse effects*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D006084:Graft Rejection / Q000532:radiotherapy; D016027:Heart Transplantation; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D015182:Lymphatic Irradiation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D013961:Thyroid Gland / Q000473:pathology
chemical_list: D000638:Amiodarone