title: Application of maximum length sequence analysis to auditory brainstem response testing of premature newborns.
abstract: The feasibility of utilizing maximum length sequence analysis (MLSA) with newborns was examined on 40 premature infants residing in a neonatal intensive care unit (NICU). Auditory brainstem responses (ABRs) were initially obtained using a conventional stimulus rate of 33.3/sec. Using MLSA, responses were also recorded using much faster stimulus rates (227.3/sec, 454.5/sec, and 909.1/sec). As expected, faster stimulus rates resulted in longer ABR component wave latencies. Less expected was the clarity of the ABRs that were obtained through MLSA. Well-defined responses were obtained from premature infants at all stimulus rates. The findings suggest that MLSA may have clinical applications to newborn hearing screening.
authors.affiliation: Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710.
authors.forename: B A
authors.initials: BA
authors.lastname: Weber
authors.forename: P A
authors.initials: PA
authors.lastname: Roush
mesh_terms: D000161:Acoustic Stimulation; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D005865:Gestational Age; D006309:Hearing / Q000502:physiology*; D006320:Hearing Tests; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D008297:Male