[A comparative evaluation of the hemodynamic effects of nitrosorbide, korinfar, obzidan and spesikor in blockade of the left branch of the bundle of His].
The paper deals with hemodynamic parameters in the greater and lesser circulations in patients with CHD concurrent with left bundle branch block. Based on the results of clinical and instrumental studies involving electrocardiography, phonocardiography and echocardiographic techniques, the authors provide early objective measures for diagnosing the hemodynamic changes occurred with development of left bundle branch block. The authors make a comparative assessment of hemodynamic effects produced by single administration of nitrosorbide, corinfar, obsidan, and spesicor in the patients examined. Nitrosorbide and corinfar improve left ventricular contractility, reduce the degree of pulmonary hypertension and right cardiac overload, while obsidan and spesicor aggravate the hemodynamic changes in patients who have CHD and left bundle branch block.
Maev
I V
IV
V'iuchnova
E S
ES
Vorob'ev
L P
LP
D000328:Adult; D002037:Bundle-Branch Block / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008297:Male; D008790:Metoprolol / Q000627:therapeutic use*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D009543:Nifedipine / Q000627:therapeutic use*; D011433:Propranolol / Q000627:therapeutic use*; D013997:Time Factors
D011433:Propranolol; D008790:Metoprolol; D009543:Nifedipine; D007548:Isosorbide Dinitrate
Sravnitel'naia otsenka gemodinamicheskikh éffektov nitrosorbida, korinfara, obzidana i spesikora pri blokade levoĭ nozhki puchka Gisa.