Sparse data analysis.
In recent years there has been a growing interest in techniques capable of analyzing sparse data, particularly gathered during Phase III clinical trials, and there is now pressure on manufacturers to obtain more kinetic and dynamic information from Phase III studies. Techniques for the analysis of sparse data are reviewed drawing on a number of examples taken from pharmacokinetic and pharmacodynamic experiments.
Aarons
L
L
Pharmacy Department, University of Manchester, UK.
D000818:Animals; D017326:Clinical Trials, Phase III as Topic / Q000706:statistics & numerical data*; D006801:Humans; D010599:Pharmacokinetics