The MPTP tale: pathway to prevention of Parkinson's disease?
Striking similarities between poisoning by the protoxin MPTP and Parkinson's disease have always been clear (Williams, 1984). Predictions that this could lead to the discovery of the cause of Parkinson's disease have not yet materialized, but the trail has not gone cold.
Williams
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A
University of Birmingham.
Waring
R
R
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics; D004032:Diet; D006801:Humans; D020267:MPTP Poisoning; D010300:Parkinson Disease / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics / Q000378:metabolism; D011725:Pyridines / Q000378:metabolism; D012307:Risk Factors
D011725:Pyridines; D003577:Cytochrome P-450 Enzyme System; D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine