title: Comparing the effects of aspartame and sucrose on motivational ratings, taste preferences, and energy intakes in humans.
abstract: This study compared the effects of four breakfast preloads on motivational ratings, taste preferences, and energy intakes of 24 normal-weight nondieting young men and women. The preloads, composed of creamy white cheese (fromage blanc), were either plain or sweetened with aspartame or sucrose. Their energy value was either 1255 or 2929 kJ (300 or 700 kcal). Taste preferences were measured before and 150 min after breakfast. Motivational ratings were obtained at 30-min intervals. The subjects ate lunch, snack, and dinner meals in the laboratory. The consumption of low-energy as opposed to high-energy breakfasts, regardless of sweetness, led to elevated motivational ratings and increased energy intakes at lunch. However, intakes at subsequent meals were the same for all preloads, and no overall compensation in energy was observed. Aspartame did not promote hunger or lead to increased energy intakes in normal-weight subjects.
authors.affiliation: Program in Human Nutrition, University of Michigan School of Public Health, Ann Arbor 48109-2029.
authors.forename: A
authors.initials: A
authors.lastname: Drewnowski
authors.forename: C
authors.initials: C
authors.lastname: Massien
authors.forename: J
authors.initials: J
authors.lastname: Louis-Sylvestre
authors.forename: J
authors.initials: J
authors.lastname: Fricker
authors.forename: D
authors.initials: D
authors.lastname: Chapelot
authors.forename: M
authors.initials: M
authors.lastname: Apfelbaum
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001066:Appetite / Q000187:drug effects*; D001218:Aspartame / Q000494:pharmacology*; D002149:Energy Intake / Q000187:drug effects*; D005260:Female; D006801:Humans; D006815:Hunger / Q000187:drug effects; D008297:Male; D008320:Maltose / Q000494:pharmacology; D009042:Motivation; D011134:Polysaccharides / Q000494:pharmacology; D012528:Satiety Response / Q000187:drug effects; D013395:Sucrose / Q000494:pharmacology*; D013649:Taste / Q000187:drug effects*
chemical_list: D011134:Polysaccharides; D013395:Sucrose; D008320:Maltose; C008315:maltodextrin; D001218:Aspartame