[The effect of amiridin on the spectral characteristics of the human EEG].
EEG testing of 28 healthy males showed that amiridine (two tablets, each 20 mg, orally at a 45-min interval) significantly enhanced alpha stability and spectral power and decreased the stability of delta activity as compared to placebo. These effects were more pronounced in the left hemisphere at rest and in the right hemisphere during mnestic activity. The perspectives of clinical application of amiridine as an antiamnestic drug are discussed in the paper.
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D000328:Adult; D000634:Aminoquinolines / Q000494:pharmacology*; D002800:Cholinesterase Inhibitors; D003071:Cognition / Q000187:drug effects; D004292:Dominance, Cerebral / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography / Q000187:drug effects* / Q000379:methods; D006801:Humans; D008297:Male; D011619:Psychotropic Drugs / Q000494:pharmacology*; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors
D000634:Aminoquinolines; D002800:Cholinesterase Inhibitors; D011619:Psychotropic Drugs; C049860:amiridine
Vliianie amiridina na spektral'nye kharakteristiki EEG cheloveka.