title: Timing and transplant materials for closure of alveolar clefts. A clinical comparison of 296 cases.
abstract: A retrospective study of bone grafting of 296 clefts (165 unilateral and 131 bilateral was required) to answer questions about the most favourable timing and the most appropriate bone graft material. The results as such are not exceptional in comparison with earlier publications by the same or other authors, but it is of special interest that operations with different graft materials applied at different times in development, in (usually) a sufficient number of cases, can be compared together. The patients have been operated on during a period of 11 years, by the same surgeons, applying the same principles and techniques. It is shown that early secondary grafting, before the eruption of the canine, results in by far, the highest success rate. Similarly, chin bone is considerably better than any other type of transplant. Aspects of general planning, timing, technique and failures are extensively discussed. Besides the afore-mentioned most significant findings, it is also concluded that the results of grafting during osteotomies are better than they appear; that tertiary grafting is extremely difficult, and requires special surgical skill; that rib grafts score as high as iliac crest grafts and that materials other than these three types of bone should be avoided.
authors.affiliation: Department of Oral and Maxillo-Facial Surgery, University of Nijmegen, The Netherlands.
authors.forename: H P
authors.initials: HP
authors.lastname: Freihofer
authors.forename: W A
authors.initials: WA
authors.lastname: Borstlap
authors.forename: A M
authors.initials: AM
authors.lastname: Kuijpers-Jagtman
authors.forename: R A
authors.initials: RA
authors.lastname: Voorsmit
authors.forename: P A
authors.initials: PA
authors.lastname: van Damme
authors.forename: K L
authors.initials: KL
authors.lastname: Heidbüchel
authors.forename: V M
authors.initials: VM
authors.lastname: Borstlap-Engels
mesh_terms: D000539:Alveolar Process / Q000002:abnormalities*; D000543:Alveoloplasty / Q000379:methods*; D016025:Bone Transplantation / Q000379:methods*; D002972:Cleft Palate / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D007085:Ilium; D008334:Mandible; D008437:Maxilla / Q000601:surgery; D010027:Osteotomy / Q000379:methods; D012189:Retrospective Studies; D012272:Ribs; D013997:Time Factors; D016896:Treatment Outcome