Amniotic fluid interleukin-8 as a marker for intraamniotic infection.
We measured the amniotic fluid Interleukin-8 (AF IL-8) levels of 80 women to see whether or not AF IL-8 levels were of value in the diagnosis of intraamniotic infection. Of twelve patients developing conventional signs of infection, 9 had an AF IL-8 concentration above 10,000 pg/ml serum. In two patients, whose baby had a serious neonatal infection, AF IL-8 concentration also exceeded 10,000 pg/ml. Only one out of 66 apparently uninfected patients had an AF IL-8 level above 10,000 pg/ml. We therefore suggest that measuring the AF IL-8 levels is of value in cases of suspected intraamniotic infection.
Puchner
T
T
Abteilung für Geburtshilfe und Gynäkologie, Landeskrankenhaus, Vöcklabruck, Austria.
Egarter
C
C
Wimmer
C
C
Lederhilger
F
F
Weichselbraun
I
I
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000276:immunology*; D002097:C-Reactive Protein / Q000032:analysis; D002585:Cesarean Section; D002821:Chorioamnionitis / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D016209:Interleukin-8 / Q000032:analysis*; D007752:Obstetric Labor, Premature / Q000175:diagnosis / Q000276:immunology; D011247:Pregnancy; D012016:Reference Values
D016209:Interleukin-8; D002097:C-Reactive Protein