Catalytic antibodies: the concept and the promise.
Catalytic antibodies both label antigenic targets and perform enzymatic functions. Since the conceivable specificities are virtually limitless, the potential of such tools is great. They can, for example, be engineered to destroy specific pathogens or tumor cells, to protect normal cells from chemotoxicity, or to activate prodrugs at the target site.
Lerner
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Scripps Research Institute, La Jolla, Calif.
D017151:Antibodies, Catalytic / Q000378:metabolism* / Q000627:therapeutic use; D001665:Binding Sites; D003198:Computer Simulation; D006801:Humans; D009369:Neoplasms / Q000201:enzymology / Q000378:metabolism; D013379:Substrate Specificity
D017151:Antibodies, Catalytic