title: Electrolyte disturbance with omeprazole therapy.
abstract: Omeprazole is an antagonist to the H+K+ ATPase of the gastric parietal cell. We report a case of severe electrolyte disturbance in a 5-year-old child treated with omeprazole associated with excessive urinary sodium loss, that responded completely to omeprazole withdrawal.
authors.affiliation: Department of Paediatric Gastroenterology, Hospital for Sick Children, London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Melville
authors.forename: A
authors.initials: A
authors.lastname: Shah
authors.forename: D
authors.initials: D
authors.lastname: Matthew
authors.forename: P
authors.initials: P
authors.lastname: Milla
mesh_terms: D002675:Child, Preschool; D004942:Esophagitis, Peptic / Q000188:drug therapy; D006801:Humans; D007714:Klippel-Feil Syndrome / Q000150:complications; D008297:Male; D009853:Omeprazole / Q000009:adverse effects*; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced*
chemical_list: D012964:Sodium; D009853:Omeprazole; D011188:Potassium