title: Assessment of zinc bioavailability: studies in rats on zinc absorption from wheat using radio- and stable isotopes.
abstract: Absorption from wheat intrinsically and extrinsically labelled with 67Zn and extrinsically labelled with 65Zn was measured from 67Zn faecal excretion and 65Zn whole-body retention in rats. There were significant differences between the extrinsically- and intrinsically-labelled 67Zn (P < 0.001), but not between the extrinsically-labelled 65Zn and intrinsically-labelled 67Zn. The effect of chicken meat on the absorption of Zn from intrinsically-labelled wheat was also studied in the rat. Mean Zn absorption from wheat and chicken meat fed separately was 18.5 and 68.2% respectively, and from a mixture of the two containing the same level of Zn was 50.1%. The apparent absorption of Zn from the composite meal was significantly higher than predicted from the results of the foods on their own (P < 0.001).
authors.affiliation: AFRC Institute of Food Research, Norwich Laboratory, Colney.
authors.forename: T E
authors.initials: TE
authors.lastname: Fox
authors.forename: S J
authors.initials: SJ
authors.lastname: Fairweather-Tait
authors.forename: J
authors.initials: J
authors.lastname: Eagles
authors.forename: S G
authors.initials: SG
authors.lastname: Wharf
mesh_terms: D000042:Absorption; D000818:Animals; D001682:Biological Availability; D002645:Chickens; D008297:Male; D008460:Meat; D051381:Rats; D017208:Rats, Wistar; D014908:Triticum; D015032:Zinc / Q000493:pharmacokinetics*; D015033:Zinc Isotopes; D015037:Zinc Radioisotopes
chemical_list: D015033:Zinc Isotopes; D015037:Zinc Radioisotopes; D015032:Zinc