title: Antenatal assessment of neurological impairment.
abstract: An unreactive cardiotocograph late in the mid-trimester led to a sequence of investigations that revealed an appropriately grown fetus, with hepatic calcification, and evidence of intrauterine infection. Ultrasound observation and stimulation of the fetus with vibration and glucose revealed altered neurophysiological responses. The profound neurological impairment was confirmed by detailed neonatal investigations.
authors.affiliation: Fetal Centre, Liverpool Maternity Hospital.
authors.forename: W G
authors.initials: WG
authors.lastname: Taylor
authors.forename: S A
authors.initials: SA
authors.lastname: Walkinshaw
authors.forename: M A
authors.initials: MA
authors.lastname: Thomson
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis; D001933:Brain Stem; D002114:Calcinosis / Q000175:diagnosis; D015148:Cardiotocography; D002644:Chickenpox / Q000150:complications / Q000151:congenital*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011379:Prognosis