title: Efficacy of intravenous plasma to transfer passive immunity in clinically healthy and clinically ill equine neonates with failure of passive transfer.
abstract: The efficacy intravenous plasma to transfer passive immunity to clinically healthy colostrum-deprived and clinically ill foals with failure of passive transfer was investigated. Efficacy of transfer was evaluated by the elevation of serum IgG per gram of IgG administered as a function of body weight. Colostrum deprived healthy foals had a significantly greater increase in serum IgG than did clinically ill foals with failure of passive transfer. Knowledge of the IgG content of plasma to be administered and the health status of a foal with failure of passive transfer should allow more accurate prediction of an individual foal's response to treatment.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853.
authors.forename: P A
authors.initials: PA
authors.lastname: Wilkins
authors.forename: S
authors.initials: S
authors.lastname: Dewan-Mix
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D003126:Colostrum / Q000276:immunology; D005260:Female; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses / Q000276:immunology*; D007112:Immunity, Maternally-Acquired; D007116:Immunization, Passive / Q000662:veterinary*; D007074:Immunoglobulin G / Q000097:blood / Q000627:therapeutic use*; D011247:Pregnancy
chemical_list: D007074:Immunoglobulin G