title: Bilateral carcinoma of the breast.
abstract: In a retrospective review of 2820 patients with breast carcinoma seen at the Combined Breast Clinic of St George's Hospital over a 23-year period 101 cases were bilateral of which 52 (1.8%) presented synchronously and 49 (1.7%) metachronously. Twenty deaths occurred in the synchronous group after a mean follow-up of 56.2 months and 15 deaths in the metachronous group after a mean follow-up of 48.5 months following diagnosis of the second tumour. If timed from initial presentation patients with metachronous tumours fared better than those with unilateral disease (P < 0.01). There was no significant difference in survival between patients with metachronous (if timed from the second tumour), synchronous or unilateral breast carcinoma.
authors.affiliation: Surgical Breast Unit, St George's Hospital, Tooting, London.
authors.forename: M D
authors.initials: MD
authors.lastname: Graham
authors.forename: A
authors.initials: A
authors.lastname: Yelland
authors.forename: J
authors.initials: J
authors.lastname: Peacock
authors.forename: N
authors.initials: N
authors.lastname: Beck
authors.forename: H
authors.initials: H
authors.lastname: Ford
authors.forename: J C
authors.initials: JC
authors.lastname: Gazet
mesh_terms: D001943:Breast Neoplasms; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D016609:Neoplasms, Second Primary; D012189:Retrospective Studies; D016019:Survival Analysis