Intermittent versus continuous administration of growth hormone treatment.
Growth hormone treatment given by daily injection was compared with growth hormone given for three weeks of every four. All children had received recombinant human growth hormone for two years before randomisation. Growth velocity decreased in both groups in years one and two of the study but the effect was significantly greater in the group receiving intermittent growth hormone.
Hakeem
V
V
Endocrine Unit, Middlesex Hospital, London.
Hindmarsh
P C
PC
Brook
C G
CG
D001827:Body Height / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy*; D013006:Growth Hormone / Q000008:administration & dosage* / Q000172:deficiency; D006801:Humans; D007267:Injections; D008297:Male; D013997:Time Factors
D013006:Growth Hormone