title: [MRI of the hyaline knee joint cartilages. Animal and clinical studies].
abstract: The value of MR imaging for the detection of hyaline cartilage lesions using 2-D spin-echo and 3-D gradient-echo imaging was evaluated in an animal experiment in 10 dogs and in a clinical study in 30 patients. MR imaging findings were compared with histopathological and arthroscopy findings, respectively. Using MRI neither grade I nor grade II hyaline cartilage lesions were detectable. In the animal experiments 77% of grade III lesions and all the grade IV lesions were seen. However, in the clinical study only about the half of grade III and IV lesions were detected. 3-D gradient-echo MR imaging was superior to 2-D spin-echo imaging (p < 0.001), while 3-D FLASH and 3-D FISP did not differ significantly in the detection rate (p < 0.34). 3-D gradient-echo MR imaging seems to be the best method for the delineation of high grade cartilage lesions. However, early stages of cartilage degeneration are invisible even with this imaging modality.
authors.affiliation: Klinik für Radiologische Diagnostik, RWTH Aachen.
authors.forename: G
authors.initials: G
authors.lastname: Adam
authors.forename: A
authors.initials: A
authors.lastname: Prescher
authors.forename: C
authors.initials: C
authors.lastname: Nolte-Ernsting
authors.forename: M
authors.initials: M
authors.lastname: Bühne
authors.forename: K
authors.initials: K
authors.lastname: Scherer
authors.forename: W
authors.initials: W
authors.lastname: Küpper
authors.forename: R W
authors.initials: RW
authors.lastname: Günther
mesh_terms: D000328:Adult; D000818:Animals; D001182:Arthroscopy; D002357:Cartilage Diseases / Q000175:diagnosis / Q000473:pathology; D002358:Cartilage, Articular / Q000033:anatomy & histology* / Q000293:injuries / Q000473:pathology; D004285:Dogs; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000033:anatomy & histology* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male
vernacular_title: MRT des hyalinen Kniegelenkknorpels. Tierexperimentelle und klinische Untersuchungen.