title: [The use of domestic viscoelastic substances in IOL implantation and their toxicity to endothelial cells in vitro].
abstract: 34 senile cataract patients were randomly divided into groups of 1% sodium hyaluronate (Healon) 14 patients, 2% hydroxypropylmethylcellulose (HPMC) 10 patients and Viscose 10 patients for extracapsular cataract extraction with IOL implantation. The rate of endothelial cell loss, the corneal thickness, the intraocular pressure, and the anterior chamber reactions were investigated; the toxicity of the viscoelastic substances on human corneal endothelial cells was studied in vitro for comparative evaluation.
authors.affiliation: Institute of Ophthalmology, Shandong Academy of Medical Sciences, Qingdao.
authors.forename: J
authors.initials: J
authors.lastname: Zeng
mesh_terms: D002386:Cataract / Q000473:pathology / Q000628:therapy*; D002452:Cell Count / Q000187:drug effects; D002478:Cells, Cultured; D003315:Cornea / Q000187:drug effects / Q000473:pathology; D004728:Endothelium, Corneal / Q000187:drug effects* / Q000473:pathology; D006801:Humans; D006820:Hyaluronic Acid / Q000009:adverse effects* / Q000633:toxicity; D065347:Hypromellose Derivatives; D007429:Intraocular Pressure / Q000187:drug effects; D007910:Lenses, Intraocular; D008747:Methylcellulose / Q000009:adverse effects / Q000031:analogs & derivatives / Q000633:toxicity
chemical_list: D065347:Hypromellose Derivatives; D006820:Hyaluronic Acid; D008747:Methylcellulose