[An analysis of the micronuclei in the oral mucosa of cancer patients for assessing the clastogenic effect of chemical preparations].
The frequency of micronuclei in the buccal mucosa cells have been investigated in healthy persons (donors) and patients with tumors before and after chemotherapy. It has been shown that frequency of micronuclei in the cells of patients before therapy and donors were at the same level. One day after chemotherapy the frequency of micronuclei was elevated 3.2 times.
Nersesian
A K
AK
Zil'fian
V N
VN
Kumkumadzhian
V A
VA
Nersesian
A K
AK
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D048629:Micronuclei, Chromosome-Defective / Q000187:drug effects* / Q000648:ultrastructure; D015162:Micronucleus Tests; D008875:Middle Aged; D009061:Mouth Mucosa / Q000187:drug effects* / Q000648:ultrastructure; D009153:Mutagens / Q000009:adverse effects*; D009369:Neoplasms / Q000188:drug therapy* / Q000648:ultrastructure*
D009153:Mutagens
Analiz mikroiader v slizistoĭ rotovoĭ polosti onkologicheskikh bol'nykh dlia otsenki klastogennogo éffekta khimiopreparatov.