Molecular follow-up of patients after bone marrow transplantation.
The follow-up of patients after bone marrow transplantation (BMT) revealed some discrepancies between red blood cell and white blood cell origin. In all six patients under study, the DNA analysis showed full engraftment, while red blood cells in some of them indicated persistence of recipient bone marrow activity. Abnormalities detected by the probe p362A (XY homologous region) in electrophoretic patterns observed during the period of graft versus host disease (GVHD) are discussed.
Brdicka
R
R
Laboratory of Molecular Genetics, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Sieglová
Z
Z
Písacka
M
M
Hrabánek
J
J
Loudová
M
M
Haskovec
C
C
D016026:Bone Marrow Transplantation; D002678:Chimera / Q000235:genetics; D004247:DNA / Q000032:analysis; D004912:Erythrocytes / Q000166:cytology; D005500:Follow-Up Studies; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
D004247:DNA