title: DNA fingerprint bands applied to linkage analysis with quantitative trait loci in chickens.
abstract: An efficient approach to detect association between quantitative traits and bands of DNA fingerprint patterns uses intra-family tail analysis, which compares fingerprints of DNA mixes from individuals at the two tails of a phenotypic distribution. In analysis of 67 paternal half-sibs of a meat-type chicken family, of 57 sire bands generated by two probes, one sire-specific band (S6.6) was associated with abdominal fat deposition. The band effect was estimated by a linear model analysis to be 0.88 standard deviations, or about 30% of the family mean. The association between band S6.6 and abdominal fat was further examined by testing progeny of paternal half-sibs of the chickens which were used in the tail analysis, establishing genetic linkage between the DNA marker and a genetic locus affecting abdominal fat deposition.
authors.affiliation: Department of Genetics, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Plotsky
authors.forename: A
authors.initials: A
authors.lastname: Cahaner
authors.forename: A
authors.initials: A
authors.lastname: Haberfeld
authors.forename: U
authors.initials: U
authors.lastname: Lavi
authors.forename: S J
authors.initials: SJ
authors.lastname: Lamont
authors.forename: J
authors.initials: J
authors.lastname: Hillel
mesh_terms: D000273:Adipose Tissue / Q000254:growth & development*; D000704:Analysis of Variance; D000818:Animals; D002645:Chickens / Q000235:genetics* / Q000254:growth & development; D003433:Crosses, Genetic; D016172:DNA Fingerprinting / Q000662:veterinary; D005260:Female; D005787:Gene Frequency; D008040:Genetic Linkage; D005819:Genetic Markers; D016014:Linear Models; D008297:Male
chemical_list: D005819:Genetic Markers