title: [A case of binswanger-type dementia with bilateral temporoparietal hypoperfusion in SPECT].
abstract: We report a case of Binswanger-type dementia demonstrated bilateral temporoparietal hypoperfusion in SPECT with 123I-IMP. The perfusion pattern in the present case was different from those previously obtained in SPECT or PET studies of patients with Binswanger-type dementia, and was similar to regional abnormalities in patients with Alzheimer-type dementia. Temporoparietal hypoperfusion in this case is likely to be mediated by neuronal mechanisms via projection fibers as a result of the deep white matter lesions in the temporoparietal area. A decreased perfusion or metabolism in the temporoparietal area is considered to be a characteristic in patients with Alzheimer-type dementia, however, we should keep in mind that other cerebral disorders may also show a similar perfusion pattern.
authors.affiliation: Department of Internal Medicine, Tachikawa General Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Hanyu
authors.forename: T
authors.initials: T
authors.lastname: Sugiyama
authors.forename: S
authors.initials: S
authors.lastname: Abe
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: H
authors.initials: H
authors.lastname: Katsunuma
authors.forename: T
authors.initials: T
authors.lastname: Asano
authors.forename: H
authors.initials: H
authors.lastname: Arai
authors.forename: M
authors.initials: M
authors.lastname: Takasaki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000662:Amphetamines; D003704:Dementia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D010477:Perfusion; D012039:Regional Blood Flow; D013702:Temporal Lobe / Q000098:blood supply*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine