[The effect of high-frequency ventilation of the lungs on the pulmonary and systemic circulations in microembolism of the pulmonary artery].
The linear and volumetric blood flow velocity in the ascending aorta and pulmonary artery conus, right-left ventricular ejection balance, pulmonary and femoral arterial blood pressures, pulmonary microcirculation in fat pulmonary microembolism induced during the routine and high-frequency jet lung ventilation (HFJLV) were studied by ultrasonic techniques in acute experiments on cats with open chest under nembutal narcosis. Pulmonary microembolism was shown to resulted in 487 and 252% increases in pulmonary vascular resistance during the routine and HFJLVs, respectively. There were also 167 and 127% increases in mean pulmonary pressure and 60 and 34% decreases in the volumetric velocity of pulmonary blood flow. The linear velocity of pulmonary blood flow was unchanged with routine lung ventilation, whereas it decreased by 68% with HFJLV. Microembolism impaired the balance between right and left ventricular ejections with blood being redistributed into the greater circulation. The imbalance lasted 5-7 min during HFJLV, while with the routine lung ventilation it was preserved up to the end of the experiment, and systemic blood pressure and total peripheral vascular resistance decreased. Alveolar edema developed in interstitial pulmonary edema. The animals' death occurred 40-60 min later.
Sanotskaia
N V
NV
Vyzhigina
M A
MA
Matsievskiĭ
D D
DD
Luk'ianov
M V
MV
Aleĭnikov
S O
SO
D000818:Animals; D001775:Blood Circulation; D002415:Cats; D004620:Embolism, Fat / Q000139:chemically induced / Q000503:physiopathology / Q000628:therapy*; D005069:Evaluation Studies as Topic; D006439:Hemodynamics; D006611:High-Frequency Jet Ventilation; D008297:Male; D000069463:Olive Oil; D010938:Plant Oils; D011652:Pulmonary Circulation; D011655:Pulmonary Embolism / Q000139:chemically induced / Q000503:physiopathology / Q000628:therapy*; D012121:Respiration, Artificial
D000069463:Olive Oil; D010938:Plant Oils
Vliianie vysokochastotnoĭ ventiliatsii legkikh na legochnoe i sistemnoe krovoobrashchenie pri mikroémbolii legochnoĭ arterii.