title: Measuring the rupture stress point of biological sealant-collagen bonding: validation of a technique used after hepatectomy.
abstract: The aim of this experimental study was to measure the rupture stress point of a fibrin clot situated on a liver, in realistic surgical conditions. The experimental method was carried out with a machined wooden cylinder bonded on the liver, connected with a wire to a setup and pulled at a constant speed, and a sensor was placed on the wire measuring the applied strength. This method, realized in the dog, made it possible to validate a precise and reproducible method designed for testing the adhesive characteristics of biological sealant-collagen bonding on the liver.
authors.affiliation: Groupe de Biochimie et Physiopathologie Digestive et Nutritionnelle, Hôpital Charles-Nicolle, Rouen, France.
authors.forename: F
authors.initials: F
authors.lastname: Michot
authors.forename: M
authors.initials: M
authors.lastname: Scotte
authors.forename: F
authors.initials: F
authors.lastname: Dujardin
authors.forename: Y
authors.initials: Y
authors.lastname: Hoebeke
authors.forename: I
authors.initials: I
authors.lastname: Le Blanc
authors.forename: A
authors.initials: A
authors.lastname: Amelot
authors.forename: P
authors.initials: P
authors.lastname: Azema
authors.forename: P
authors.initials: P
authors.lastname: Bouvier
mesh_terms: D000268:Adhesiveness; D000818:Animals; D003094:Collagen; D004285:Dogs; D015718:Fibrin Tissue Adhesive / Q000494:pharmacology*; D006498:Hepatectomy / Q000379:methods*; D013718:Tensile Strength
chemical_list: D015718:Fibrin Tissue Adhesive; D003094:Collagen