title: Chromosome structure inside the nucleus.
abstract: Recent in situ three-dimensional structural studies have provided a new model for the 30 nm chromatin fiber. In addition, research during the past year has revealed some of the molecular complexity of non-histone chromosomal proteins. Still to come is the unification of molecular insights with chromosomal architecture.
authors.affiliation: Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco 94143-0554.
authors.forename: J R
authors.initials: JR
authors.lastname: Swedlow
authors.forename: D A
authors.initials: DA
authors.lastname: Agard
authors.forename: J W
authors.initials: JW
authors.lastname: Sedat
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D002875:Chromosomes / Q000648:ultrastructure*; D006801:Humans; D009687:Nuclear Proteins / Q000737:chemistry; D011487:Protein Conformation
chemical_list: D009687:Nuclear Proteins