Reduced control of motor output in a human hand muscle of elderly subjects during submaximal contractions.
1. The effect of age on the motor output of the first dorsal interosseous muscle of 22 (6 female, 16 male) human subjects was investigated. The purpose of the study was to determine the effect of age on the control of muscle force and the associated changes in the discharge behavior and mechanical properties of single motor units. 2. Each subject performed three tasks requiring isometric abduction of the left index finger: a maximum voluntary contraction (MVC), a constant-force task, and a threshold task. The ability to control force was assessed during the constant-force task by quantifying the variation in isometric force about four submaximal target forces (5, 20, 35, and 50% MVC). The threshold task involved sustaining the discharge of the isolated motor unit at a low, steady rate for approximately 3 min. 3. The discharge behavior and the mechanical properties of single motor units were determined during the threshold task by measuring the interimpulse intervals and the peak amplitude and time to peak of the spike-triggered average force. 4. The data indicated that age had an effect on the variation of force about submaximal target forces (range: 5-50% MVC), and that these force variations, when calculated relative to the target force, were greater at lower force levels in the elderly subjects.(ABSTRACT TRUNCATED AT 250 WORDS)
Galganski
M E
ME
Department of Exercise, University of Arizona, Tucson 85721.
Fuglevand
A J
AJ
Enoka
R M
RM
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D004576:Electromyography; D005260:Female; D006225:Hand / Q000294:innervation / Q000502:physiology*; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology; D009132:Muscles / Q000294:innervation / Q000502:physiology*; D011999:Recruitment, Neurophysiological / Q000502:physiology