title: Expression of the exoglucanase gene in yeast and hyphal forms of Candida albicans.
abstract: The gene for the beta-(1,3) exoglucanase of Candida albicans was used as a probe to detect transcripts of related genes in C. albicans and in several other Candida species. A single homologous transcript was detected in all of the species tested. Expression of the exoglucanase gene in C. albicans was found to be coincident with the onset of growth and the levels of the transcript were proportional to the growth rate. Comparable levels of the transcript were produced during yeast and hyphal forms of growth.
authors.affiliation: Biochemistry Department, University of Otago, Dunedin, New Zealand.
authors.forename: R S
authors.initials: RS
authors.lastname: Chambers
authors.forename: P A
authors.initials: PA
authors.lastname: Sullivan
mesh_terms: D015152:Blotting, Northern; D002175:Candida / Q000201:enzymology / Q000235:genetics; D002176:Candida albicans / Q000201:enzymology / Q000235:genetics* / Q000502:physiology; D015971:Gene Expression Regulation, Enzymologic; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D043326:Glucan 1,3-beta-Glucosidase; D007700:Kinetics; D010940:Plant Proteins / Q000235:genetics; D012331:RNA, Fungal / Q000096:biosynthesis / Q000302:isolation & purification; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics*; D013045:Species Specificity; D014158:Transcription, Genetic; D001617:beta-Glucosidase / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D010940:Plant Proteins; D012331:RNA, Fungal; D001617:beta-Glucosidase; D043326:Glucan 1,3-beta-Glucosidase