title: Circadian variations of superoxide dismutase activity in the rat pineal gland.
abstract: The 24 h profile of the activity of the antioxidant enzyme superoxide dismutase (SOD) in the pineal gland of rats was studied. Rhythmic analysis showed a significant 24 h rhythm with an amplitude of oscillation of 25% of the 24 h mean value, that was 100.34 +/- 1.6 U SOD (nitrite). An ultradian rhythm of 9 h was also detected. The diurnal profile of superoxide dismutase activity is discussed in relation to the oxidative metabolism of the pineal gland.
authors.affiliation: Department of Physiology and Biophysics, Universidade de São Paulo, Brazil.
authors.forename: J
authors.initials: J
authors.lastname: Cipolla-Neto
authors.forename: D S
authors.initials: DS
authors.lastname: Abdalla
authors.forename: R P
authors.initials: RP
authors.lastname: Markus
authors.forename: A
authors.initials: A
authors.lastname: Campa
mesh_terms: D000204:Activity Cycles / Q000502:physiology; D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism; D002940:Circadian Rhythm / Q000502:physiology*; D008297:Male; D008550:Melatonin / Q000378:metabolism; D010870:Pineal Gland / Q000201:enzymology*; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D015306:Biogenic Monoamines; D013482:Superoxide Dismutase; D008550:Melatonin