The kinin system in inflammation.
Bradykinin and related kinins are important mediators of most kinds of inflammation. Mechanisms of kinin production in injury, infection and immune system activation are discussed. Bradykinin antagonists show great promise for development of new drugs for inflammation.
Stewart
J M
JM
University of Colorado School of Medicine, Department of Biochemistry, Denver 80262.
D000595:Amino Acid Sequence; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D001920:Bradykinin / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D007705:Kinins / Q000502:physiology*; D008969:Molecular Sequence Data
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007705:Kinins; D001920:Bradykinin