title: Studies on chemotherapy of parasitic helminths: efficacy of artemether on Japanese strain of Schistosoma japonicum in mice.
abstract: Effects of artemether were examined on Schistosoma japonicum in mice. When the drug was given at a daily dosage of 200 mg/kg for 4 successive days from 46 days post-infection, a significant reduction in worm recovery was observed. A significant reduction in size of worms from the medicated mice was also seen compared with that from non-medicated controls.
authors.affiliation: Department of Parasitology, Hamamatsu University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Sano
authors.forename: C V
authors.initials: CV
authors.lastname: Akyol
authors.forename: A
authors.initials: A
authors.lastname: Tungtrongchitr
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: A
authors.initials: A
authors.lastname: Ishih
mesh_terms: D000818:Animals; D000077549:Artemether; D037621:Artemisinins; D005260:Female; D051379:Mice; D012549:Schistosoma japonicum / Q000187:drug effects; D012554:Schistosomiasis japonica / Q000188:drug therapy*; D012556:Schistosomicides / Q000627:therapeutic use*; D012717:Sesquiterpenes / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D037621:Artemisinins; D012556:Schistosomicides; D012717:Sesquiterpenes; D000077549:Artemether