title: Urinary N-acetyl-beta-D-glucosaminidase and beta-aminoisobutyric acid in workers occupationally exposed to metals such as chromium, nickel, and iron.
abstract: To examine the relationships between the urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG) and beta-aminoisobutyric acid (AIBA) as a metabolite of thymine, and exposure to chromium, nickel, and iron, we determined these parameters in 58 workers engaged in the cutting and grinding of stainless steel or iron-steel plates. A significant increase in urinary NAG activity or urinary AIBA excretion was found in some of these workers. However, we could not find a significant positive correlation between the urinary excretion of NAG or AIBA and the urinary concentration of chromium, nickel, or iron as an indicator of internal dose.
authors.affiliation: Department of Community Health Science, Saga Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tomokuni
authors.forename: M
authors.initials: M
authors.lastname: Ichiba
authors.forename: Y
authors.initials: Y
authors.lastname: Hirai
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine*; D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects; D000621:Aminoisobutyric Acids / Q000652:urine*; D002857:Chromium / Q000009:adverse effects / Q000652:urine; D006801:Humans; D007501:Iron / Q000009:adverse effects / Q000652:urine; D008297:Male; D008670:Metals / Q000009:adverse effects*; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects / Q000652:urine; D016273:Occupational Exposure / Q000009:adverse effects*
chemical_list: D000395:Air Pollutants, Occupational; D000621:Aminoisobutyric Acids; D008670:Metals; D002857:Chromium; D009532:Nickel; D007501:Iron; D000118:Acetylglucosaminidase; C033435:3-aminoisobutyric acid