[Effect of nonselective beta-adrenergic blockade on blood plasma levels of glucagon in plasma during insulin-induced hypoglycemia].
An effect of nonselective beta-adrenergic blockade with propranolol on the blood plasma level of glucagon during insulin-induced hypoglycemia was studies in 20 control dogs and 20 alloxan diabetic dogs. Increased sensitivity to exogenous insulin and prolonged hypoglycemia were noted during nonselective beta-adrenergic blockade. However, glucagon response to insulin-induced hypoglycemia following propranolol administration was increased.
Szelechowska
M
M
Kliniki Endokrynologii AM, Białymstoku.
Kinalska
I
I
D000818:Animals; D004285:Dogs; D005934:Glucagon / Q000097:blood*; D007003:Hypoglycemia / Q000097:blood* / Q000139:chemically induced; D007328:Insulin; D011433:Propranolol / Q000494:pharmacology*
D007328:Insulin; D005934:Glucagon; D011433:Propranolol
Wpływ niewybiórczej blokady beta-adrenergicznej na stezenie glukagonu w osoczu w hipoglikemii poinsulinowej.