title: Lymphoplasmacytic lymphoma in a stallion.
abstract: Lymphoplasmacytic lymphoma found in a 6-year-old Anglo-Arabian stallion was investigated histologically, immunohistochemically and ultrastructurally. The animal showed a large mediastinal mass and generalized lymph node involvement. The neoplastic cells were in various differentiation stages of small lymphocyte, centrocyte, centroblast, immunoblast and plasma cell. Some neoplastic cells showed positive cytoplasmic reactivity for mu and lambda chains. There were well developed rough endoplasmic reticulum (RER) and Golgi complexes in plasmacytoid cells, and slightly developed RER or a few long strands of RER in medium-sized to large lymphoid cells. These findings suggest that this neoplasm is of B-cell origin.
authors.affiliation: Chuo Meat Inspection Office, Kochi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Fukunaga
authors.forename: M
authors.initials: M
authors.lastname: Ninomiya
authors.forename: Y
authors.initials: Y
authors.lastname: Oohara
authors.forename: K
authors.initials: K
authors.lastname: Kusunose
authors.forename: Y
authors.initials: Y
authors.lastname: Okamura
authors.forename: H
authors.initials: H
authors.lastname: Nagasaki
authors.forename: S
authors.initials: S
authors.lastname: Ishino
authors.forename: K
authors.initials: K
authors.lastname: Kadota
mesh_terms: D000818:Animals; D006734:Horse Diseases; D006736:Horses; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007142:Immunoglobulin gamma-Chains / Q000032:analysis; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D008198:Lymph Nodes / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D008854:Microscopy, Electron
chemical_list: D007147:Immunoglobulin Light Chains; D007142:Immunoglobulin gamma-Chains