title: Symmetrical transcription in the tRNA region of the mitochondrial genome of Saccharomyces cerevisiae.
abstract: The occurrence of discrete transcripts originating from the non-coding strand of the yeast mitochondrial genome is described. The region under investigation is localized in the large tRNA gene cluster between the LSU ribosomal RNA and OXI 1 genes. The transcripts originating from the non-coding strand were detected in a wild-type strain and in a rho- mutant. Their size range includes transcripts of about 2000 nucleotides able to accommodate more than one "anti-tRNA". In some cases their extremities can be mapped near highly-conserved nonanucleotides that could function as origins of transcription. The involvement of the tRNA-processing machinery in the cleavage of these transcripts is also hypothesized.
authors.affiliation: Department of Developmental and Cell Biology, University of Rome, La Sapienza, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Grisanti
authors.forename: S
authors.initials: S
authors.lastname: Francisci
authors.forename: P
authors.initials: P
authors.lastname: Tataseo
authors.forename: C
authors.initials: C
authors.lastname: Palleschi
mesh_terms: D001483:Base Sequence; D015152:Blotting, Northern; D004271:DNA, Fungal; D004272:DNA, Mitochondrial / Q000235:genetics*; D016681:Genome, Fungal; D007438:Introns; D008969:Molecular Sequence Data; D005810:Multigene Family; D012323:RNA Processing, Post-Transcriptional; D012331:RNA, Fungal / Q000235:genetics*; D012343:RNA, Transfer / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D004271:DNA, Fungal; D004272:DNA, Mitochondrial; D012331:RNA, Fungal; D012343:RNA, Transfer