title: In vitro comparison of bileaflet aortic heart valve prostheses. St. Jude Medical, CarboMedics, modified Edwards-Duromedics, and Sorin-Bicarbon valves.
abstract: The hydrodynamic performance of four currently used bileaflet heart valve prostheses (St. Jude Medical, CarboMedics, modified Edwards-Duromedics, and Sorin-Bicarbon) with a nominal tissue anulus diameter of 27 mm were measured in the aortic position. All experiments were performed in nonpulsatile flow and in an electrohydraulic, computer-controlled pulse duplicator simulating the left side of the human circulatory system. Testing conditions were set at cardiac outputs of 3.0, 4.5, 6.5, and 8.0 L/min at a constant heart rate of 70 beats/min. The Sorin-Bicarbon valve had the lowest pressure difference with regard to nonpulsatile (mean 5.4 mm Hg at 30 L/min) and pulsatile (mean 2.2 mm Hg at 8 L/min) flow, followed by the St. Jude Medical, CarboMedics, and modified Edwards-Duromedics valves. The leakage volumes under static and pulsatile flow conditions were lowest for the modified Edwards-Duromedics and Sorin-Bicarbon valves. The energy loss in pulsatile flow was lowest for the Sorin-Bicarbon valve, mainly because its systolic, closure, and leakage energy losses were low. Systolic sequential velocity profiles showed the most even flow distribution pattern for the St. Jude Medical and Sorin-Bicarbon valves. These findings correspond with lower overall Reynolds shear stress levels for the St. Jude Medical and the Sorin-Bicarbon valves than for the modified Edwards-Duromedics and CarboMedics valves.
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Aachen University of Technology, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Reul
authors.forename: J A
authors.initials: JA
authors.lastname: van Son
authors.forename: U
authors.initials: U
authors.lastname: Steinseifer
authors.forename: B
authors.initials: B
authors.lastname: Schmitz
authors.forename: A
authors.initials: A
authors.lastname: Schmidt
authors.forename: C
authors.initials: C
authors.lastname: Schmitz
authors.forename: G
authors.initials: G
authors.lastname: Rau
mesh_terms: D001021:Aortic Valve / Q000502:physiology*; D001696:Biomechanical Phenomena; D001783:Blood Flow Velocity; D006350:Heart Valve Prosthesis; D006801:Humans; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D011312:Pressure; D011673:Pulsatile Flow; D012212:Rheology; D013599:Systole