title: [Acute toxicity of zidovudine. Analysis of the literature and number of cases at the Paris Poison Control Center].
abstract: 13 cases of zidovudine overdosage have been previously published; 30 have been notified to Paris Control Poison Centre up to January 1991. This analysis shows that acute toxicity appears infrequent and mild when ingested dose is lower than 25 gr. However it appears from this series that an haematologic monitoring is needed because of the risk of myelosuppression.
authors.affiliation: Centre Anti-Poisons de Paris, Hôpital Fernand Widal.
authors.forename: F
authors.initials: F
authors.lastname: Maignen
authors.forename: S
authors.initials: S
authors.lastname: Meglio
authors.forename: I
authors.initials: I
authors.lastname: Bidault
authors.forename: A
authors.initials: A
authors.lastname: Castot
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D062787:Drug Overdose; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010297:Paris; D011039:Poison Control Centers; D015215:Zidovudine / Q000378:metabolism / Q000506:poisoning*
chemical_list: D015215:Zidovudine
vernacular_title: Toxicité aiguë de la zidovudine. Analyse de la littérature et des cas notifiés au centre Anti-Poisons de Paris.