Radioassays of yttrium-90 used in nuclear medicine.
Yttrium-90 radioassays are required in nuclear medicine at the gigabecquerel activity level (GBq) for measuring injected activity, and at the becquerel level for measuring individual tissue samples in biodistribution studies. A method of standardizing 90Y for activity using high-efficiency liquid-scintillation counting is described. Solution standards were used to establish the calibration factors for commercial radionuclide calibrators. Detection efficiencies are also presented for liquid-scintillation counting, NaI(T1) bremsstrahlung counting and Cerenkov counting.
Coursey
B M
BM
Ionizing Radiation Division, NIST, Technology Administration, Gaithersburg, MD 20899.
Calhoun
J M
JM
Cessna
J T
JT
D009683:Nuclear Medicine; D012588:Scintillation Counting / Q000379:methods; D014018:Tissue Distribution; D015021:Yttrium Radioisotopes / Q000032:analysis* / Q000493:pharmacokinetics / Q000627:therapeutic use
D015021:Yttrium Radioisotopes