title: [Relationship of histocompatibility groups to chronic HBV infections].
abstract: HLA-A, B, C and DR locus specificities studied in 168 patients (71 Chronic active Hepatitis, 97 Chronic Persistent Hepatitis) serologically and histopathologically proven Chronic Hepatitis B Virus infection. There were 113 men and 55 women with a mean age of 23.2 (21-52) years. Hundred and seventy four healthy subjects (107 men, 67 women) included in control group with a mean age of 26.4 (20-54) years. The frequency of HLA A3 (p < 0.01), HLA A11 (p < 0.01), HLA B35 (p < 0.05) and HLA B51 (p < 0.01) were significantly higher in patients than in healthy control subjects. Comparisons among the other HLA-A, B, C and DR locus were found to be statistically non-significant.
authors.affiliation: Enfeksiyon Hastaliklari ve Klinik Bakteriyoloji ve Enfeksiyon Hastaliklari Anabilim Dali Başkani.
authors.forename: A
authors.initials: A
authors.lastname: Hacibektaşoğlu
authors.forename: A
authors.initials: A
authors.lastname: Barut
authors.forename: A
authors.initials: A
authors.lastname: Inal
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006680:HLA Antigens / Q000097:blood*; D015234:HLA-A Antigens / Q000097:blood; D059870:HLA-A11 Antigen; D015791:HLA-A3 Antigen / Q000097:blood; D015235:HLA-B Antigens / Q000097:blood; D015797:HLA-B35 Antigen / Q000097:blood; D059949:HLA-B51 Antigen; D015236:HLA-C Antigens / Q000097:blood; D006684:HLA-DR Antigens / Q000097:blood; D006509:Hepatitis B / Q000276:immunology*; D006521:Hepatitis, Chronic / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; D059870:HLA-A11 Antigen; D015791:HLA-A3 Antigen; D015235:HLA-B Antigens; D015797:HLA-B35 Antigen; D059949:HLA-B51 Antigen; D015236:HLA-C Antigens; D006684:HLA-DR Antigens
vernacular_title: Kronik HBV enfeksiyonu ile doku gruplari arasindaki ilişki.