[Scleromyxedema associated with myopathy].
We describe a 45 year-old man, with scleromyxedema associated to systemic manifestations, including myopathy. After 6 years of dermatologic manifestations, muscular weakness, with proximal predominance resulting in incapacity, was established. Corticosteroids plus cyclophosphamide treatment suppressed muscular symptomatology, and a second biopsy was normal. The common association between scleromyxedema and myopathy and other systemic alterations suggest that this entity should probably be considered as a systemic disease instead as a skin disease.
Catalá
J
J
Servicio de Neurología, Hospital La Fe, Valencia.
López-Aldeguer
J
J
Vílchez
J J
JJ
Chirivella
M
M
Catalá
M T
MT
D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D008010:Lichen Planus / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000150:complications* / Q000188:drug therapy; D009230:Myxedema / Q000150:complications* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use
D003520:Cyclophosphamide; D011241:Prednisone
Escleromixedema asociado a miopatía.