Salivary effects on polymorphonuclear leukocyte functions.
Respiratory burst, enzymatic degranulation and bacterial killing were investigated on peripheral blood polymorphonuclear leukocytes (polymorphonuclear leukocytes) incubated with a pool of salivary fluids elicited from healthy donors. Low saliva concentrations primed polymorphonuclear leukocytes for enhancement of O2 consumption, O2- and beta-glucuronidase release and Staphylococcus aureus killing. Whole saliva, on the contrary, depressed all tested phagocytic activities.
Fumarulo
R
R
Department of Biomedical Sciences, University of Bari, Italy.
Giordano
D
D
Laforgia
A
A
Larocca
A
A
Quarto
M
M
D000328:Adult; D005966:Glucuronidase / Q000378:metabolism; D006801:Humans; D009504:Neutrophils / Q000378:metabolism / Q000502:physiology*; D010101:Oxygen Consumption; D010587:Phagocytosis / Q000502:physiology; D016897:Respiratory Burst; D012463:Saliva / Q000201:enzymology / Q000502:physiology*
D005966:Glucuronidase