title: [Peutz-Jeghers syndrome with malignization of hamartomatous polyp].
abstract: Peutz-Jeghers syndrome is characterized by hamartomatous polyps in the gastrointestinal tract associated with mucocutaneous melanin spots; the condition is inherited in an autosomic dominant fashion. Although the hamartomatous polyps are not regarded as malignant, there is an association between the Peutz-Jeghers syndrome and the development of carcinomas of the gastrointestinal tract. Similarly, there is an increasing evidence suggesting that hamartomas can give rise to adenocarcinomas. We present a patient with Peutz-Jeghers syndrome who developed an adenocarcinoma in an hamartomatous jejunal polyp.
authors.affiliation: II Cátedra de Cirugía, Hospital Clínico Universidad Complutense, Madrid.
authors.forename: J M
authors.initials: JM
authors.lastname: Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: Picardo
authors.forename: A J
authors.initials: AJ
authors.lastname: Torres
authors.forename: M
authors.initials: M
authors.lastname: García Calvo
authors.forename: L
authors.initials: L
authors.lastname: Ortega
authors.forename: S
authors.initials: S
authors.lastname: Martínez
authors.forename: J L
authors.initials: JL
authors.lastname: Balibrea
mesh_terms: D000230:Adenocarcinoma; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms; D008875:Middle Aged; D010580:Peutz-Jeghers Syndrome / Q000473:pathology*; D011230:Precancerous Conditions
vernacular_title: Síndrome de Peutz-Jeghers con malignización de un pólipo hamartomatoso.