The glomerular peripolar cell.
The PPC is a distinctive granulated epithelial cell at the vascular pole of the glomerulus. It is present in a wide range of animal species. It is especially prominent in sheep, particularly the newborn lamb. To date, it has been shown that its granules contain albumin, immunoglobulins, neuron-specific enolase and transthyretin. It does not appear to contain renin. The function of the PPC awaits clarification. It has been postulated that it may play a role in the synthesis and secretion of factors involved in modulating renal tubular function.
Alcorn
D
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Department of Anatomy, University of Melbourne, Parkville, Victoria, Australia.
Ryan
G B
GB
D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004847:Epithelial Cells; D006651:Histocytochemistry; D006801:Humans; D007678:Kidney Glomerulus / Q000166:cytology* / Q000196:embryology / Q000378:metabolism; D008854:Microscopy, Electron; D012756:Sheep