[Platelet aggregation and receptor expression of low affinity to IgE (Fc epsilon RII CD23) in patients with seasonal allergic rhinitis].
In 12 patients with pollinosis analysis of platelet function was carried out. Platelet function was assessed basing on the thromboelastogram curve and aggregation capability induced by ADP. Total serum IgE levels, as well as, specific antibodies to grass pollens, IgE and IgG4 levels and circulating receptor of low IgE affinity (sFc epsilon RII/sCD23) were also analysed. The study was carried out in a dynamic state, during natural allergen exposition and natural remission. A significant correlation was found between loss of platelet function and sCD23 levels. The observed relations were not influenced by seasonal changes.
Rogala
B
B
Katedry i Kliniki Chorób Wewnetrznych i Alergologii Kierownik.
Gumprecht
J
J
Strojek
K
K
Rogala
E
E
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D010974:Platelet Aggregation / Q000276:immunology*; D011058:Pollen / Q000276:immunology*; D017455:Receptors, IgE / Q000032:analysis*; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*
D000906:Antibodies; D007074:Immunoglobulin G; D017455:Receptors, IgE; D007073:Immunoglobulin E
Agregacja płytek i ekspresja receptora o niskim powinowactwie dla IgE Fc epsilon RII (CD23) u chorych na pyłkowice.