title: [Use of molecular genetic diagnosis of malignant hyperthermic syndrome (MHS) in selection of pigs].
abstract: Recently, a mutation has been discovered in the ryanodine-receptor gene causing malignant hyperthermic syndrome (MHS) in pigs. Taking advantage of the RCR analysis of tissue samples from pigs of the Deutch Landeras breed we could have demonstrated that the gene-diagnostics MHS analysis is a simple, reliable and significant way of gene-typing for the stress resistance. Employing this test with sufficient reliability and effectively will make it possible to create homozygous stress resistant lines and to produce heterozygous stress resistant animals having both good meat quality tending to improvement and good feeding characters. The advantages of this first gene--technological technique just ready for application in animal breeding seem to ensure its quick implementation into the applied pig breeding.
authors.forename: G
authors.initials: G
authors.lastname: Brém
authors.forename: B
authors.initials: B
authors.lastname: Brening
mesh_terms: D000818:Animals; D001483:Base Sequence; D015698:Genomic Library; D005838:Genotype; D008305:Malignant Hyperthermia / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D008969:Molecular Sequence Data; D009124:Muscle Proteins / Q000235:genetics; D016133:Polymerase Chain Reaction; D019837:Ryanodine Receptor Calcium Release Channel; D012641:Selection, Genetic; D013552:Swine; D013553:Swine Diseases / Q000235:genetics*; D013577:Syndrome
chemical_list: D009124:Muscle Proteins; D019837:Ryanodine Receptor Calcium Release Channel
vernacular_title: Ispol'zovanie v selektsii svineĭ molekuliarnoĭ gennoĭ diagnostiki zlokachestvennogo gipertermicheskogo sindroma (MHS).