title: Paradoxical changes in iodine-131 scintigraphic findings in advanced follicular thyroid cancer.
abstract: We present the findings on iodine-131 (131I) scintigraphy, thallium-201 (201Tl) scintigraphy and quantitative thyroglobulin (QTG) estimation in two patients with follicular carcinoma of the thyroid with extensive metastases. The lesions were initially seen on 131I scintigraphs, but were not subsequently visualized with scanning doses of 131I (5 mCi), while retaining their ability to produce increasing amounts of thyroglobulin and take up 201Tl. Implications in choosing the appropriate diagnostic tests in the management of differentiated thyroid cancer are discussed.
authors.affiliation: Department of Radiation Oncology and Nuclear Medicine, Hahnemann University, Philadelphia, PA 19102-1192.
authors.forename: L
authors.initials: L
authors.lastname: Krishna
authors.forename: S
authors.initials: S
authors.lastname: Dadparvar
authors.forename: L W
authors.initials: LW
authors.lastname: Brady
authors.forename: B
authors.initials: B
authors.lastname: Micaily
authors.forename: M
authors.initials: M
authors.lastname: Meihofer
authors.forename: W J
authors.initials: WJ
authors.lastname: Slizofski
authors.forename: S J
authors.initials: SJ
authors.lastname: Brown
authors.forename: A
authors.initials: A
authors.lastname: Chevres
authors.forename: R
authors.initials: R
authors.lastname: Roman
authors.forename: A S
authors.initials: AS
authors.lastname: Khan
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000628:therapy; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes; D013954:Thyroglobulin / Q000097:blood; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy; D013997:Time Factors
chemical_list: D007457:Iodine Radioisotopes; D013794:Thallium Radioisotopes; D013954:Thyroglobulin