title: [Chronic lipogranuloma (paraffin granuloma) of the eyelids and orbits after endonasal paranasal sinus operation].
abstract: During the last five years 10 patients received surgical treatment in our eye clinic for tumours of the eyelids and the orbit that had developed after endonasal sinus surgery. In most patients the first signs of lid or orbital involvement had occurred 4 weeks after ENT surgery and after a unilateral or bilateral postoperative haematoma had subsided. The histological examination of the surgical specimens showed chronic sclerosing lipogranuloma containing large vacuoles surrounded by epithelioid and giant cells, typical of a so-called paraffin granuloma. MR-spectroscopy detected high concentrations of paraffin in the specimens of 3 patients. Since paraffin is a constituent of many ointments, we assume that the granulomatous reaction was elicited by the ointment tampons routinely applied to the wound area following sinus surgery. The bleeding acted as a vehicle to distribute the paraffin into the surrounding tissues.
authors.affiliation: Universitäts-Augenklinik Freiburg.
authors.forename: K
authors.initials: K
authors.lastname: Geiger
authors.forename: H
authors.initials: H
authors.lastname: Witschel
authors.forename: C
authors.initials: C
authors.lastname: Büttner
mesh_terms: D000328:Adult; D004724:Endoscopy; D015521:Ethmoid Sinusitis / Q000473:pathology / Q000601:surgery*; D005141:Eyelid Diseases / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D005143:Eyelids / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006099:Granuloma / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D015523:Maxillary Sinusitis / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009915:Orbit / Q000473:pathology; D009916:Orbital Diseases / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D010232:Paraffin / Q000008:administration & dosage / Q000009:adverse effects*; D011183:Postoperative Complications / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D012086:Reoperation
chemical_list: D010232:Paraffin
vernacular_title: Chronische Lipogranulome (Paraffingranulome) der Lider und der Orbita nach endonasaler Nebenhöhlenoperation.