title: Non-leaking amperometric biosensors based on high-molecular ferrocene derivatives.
abstract: Poly(ethylene glycol)-bound ferrocene derivatives, synthesized after activation of ferrocene carboxylic acid with 1,1'-bis carbonyl diimidazol, are able to transfer electrons from the active site of reduced glucose oxidase to electrode surfaces. This opens a route to non-leaking mediated enzyme electrodes for the determination of glucose.
authors.affiliation: Lehrstuhl für Allgemeine Chemie und Biochemie, Technische Universität München, Freising-Weihenstephan, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Schuhmann
mesh_terms: D015374:Biosensing Techniques; D002374:Catalase; D005296:Ferrous Compounds; D005947:Glucose / Q000032:analysis*; D005949:Glucose Oxidase / Q000378:metabolism; D007202:Indicators and Reagents; D007700:Kinetics; D000075163:Metallocenes; D009942:Organometallic Compounds; D011092:Polyethylene Glycols
chemical_list: D005296:Ferrous Compounds; D007202:Indicators and Reagents; D000075163:Metallocenes; D009942:Organometallic Compounds; C032949:ferrocenecarboxylic acid; D011092:Polyethylene Glycols; D005949:Glucose Oxidase; D002374:Catalase; D005947:Glucose; C004998:ferrocene