title: Two deaths involving isoflurane abuse.
abstract: Two deaths due to isoflurane abuse are reported. One case was a suicide and the other a multiple drug death including isoflurane. A simple headspace gas chromatographic method was used for isoflurane quantitation. A review of the literature did not reveal blood and tissue concentrations of isoflurane. Drug tissue distributions and a discussion of the toxicological findings are presented.
authors.affiliation: DoD Drug Detection Quality Control Laboratory, Armed Forces Institute of Pathology, Washington, DC.
authors.forename: J J
authors.initials: JJ
authors.lastname: Kuhlman
authors.forename: J
authors.initials: J
authors.lastname: Magluilo
authors.forename: B
authors.initials: B
authors.lastname: Levine
authors.forename: M L
authors.initials: ML
authors.lastname: Smith
mesh_terms: D000328:Adult; D002849:Chromatography, Gas; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage / Q000032:analysis* / Q000493:pharmacokinetics; D008297:Male; D019966:Substance-Related Disorders / Q000175:diagnosis*; D014018:Tissue Distribution
chemical_list: D007530:Isoflurane