title: [Hypothalamic astrocytoma presenting as obesity with hypogonadism].
abstract: We report herein a case of a 30 year old male patient who consulted for a long standing obesity since childhood. Clinical examination reveals the presence of hypogonadism and gynecomastia without galactorrhea. Endocrine assessment showed an hypogonadotrophic hypogonadism with a moderate insufficiency of the adrenocortical axis. Neuro-ophthalmological examination disclosed an inferior bitemporal quadranopsia. MRI showed an extra-axial suprasellar mass, lightly hypointense in T1 and hyperintense in T2. After craniotomy and conservative biopsy, pathological examination of the tumor showed regular cells surrounded with collagen and reticulin marked with immunoperoxidase against S100 protein and GFAP (glial fibrinolytic acidic protein) strongly suggesting the diagnosis of juvenile pilocytic astrocytoma.
authors.affiliation: Département de médecine, Hôpital Notre-Dame, Sherbrooke Est. Montréal, Quebec.
authors.forename: N
authors.initials: N
authors.lastname: Adingra-Groga
authors.forename: O
authors.initials: O
authors.lastname: Serri
authors.forename: F
authors.initials: F
authors.lastname: Robert
authors.forename: H
authors.initials: H
authors.lastname: Beauregard
authors.forename: J
authors.initials: J
authors.lastname: Lesage
authors.forename: M
authors.initials: M
authors.lastname: Bojanowski
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis*; D007029:Hypothalamic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D009767:Obesity, Morbid / Q000175:diagnosis*
vernacular_title: Astrocytome hypothalamique se présentant comme une obésité avec hypogonadisme.