title: [Effect of ethanol on carboxypeptidase H in the rat brain].
abstract: It is established that under a single-dose introduction of ethanol activity of carboxypeptidase H increases. During chronic consumption of ethanol changes of enzyme activity was less than during a single-dose introduction of ethanol. Most considerable changes in carboxypeptidase H activity are observed in the pituitary gland, hypothalamus and striatum. Ethanol effect on the activity of membrane-bound and soluble forms of enzyme was distinguished. It is supposed that carboxypeptidase H is involved into the formation of response to ethanol.
authors.forename: M T
authors.initials: MT
authors.lastname: Gengin
authors.forename: A N
authors.initials: AN
authors.lastname: Vernigora
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D043423:Carboxypeptidase H; D002268:Carboxypeptidases / Q000187:drug effects*; D003342:Corpus Striatum / Q000187:drug effects; D004334:Drug Administration Schedule; D000431:Ethanol / Q000008:administration & dosage*; D007031:Hypothalamus / Q000187:drug effects; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects; D051381:Rats; D012995:Solubility
chemical_list: D000431:Ethanol; D002268:Carboxypeptidases; D043423:Carboxypeptidase H
vernacular_title: Vliianie étanola na aktivnost' karboksipeptidazy H b mozge krys.