title: [Growth rate analysis of pulmonary metastases in giant cell tumor of bone].
abstract: We reviewed six cases with pulmonary metastases in giant cell tumor of bone. The growth rate and the doubling time of pulmonary metastases was measured and compared to the clinical course. The six cases were classified into two each of the following three types: 1) spontaneous remission, 2) continuously slow growing and 3) rapid growing. A favorable factor was a doubling time of more than 80 days in pulmonary metastases. A poor prognosis was indicated by a doubling time of around 30 days. Aggressive primary lesions should be excised widely.
authors.affiliation: Dept. of Orthopaedic Surgery, Nihon University School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Osaka
authors.forename: M
authors.initials: M
authors.lastname: Toriyama
authors.forename: E
authors.initials: E
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Kawano
authors.forename: K
authors.initials: K
authors.lastname: Taira
authors.forename: M
authors.initials: M
authors.lastname: Ohata
authors.forename: M
authors.initials: M
authors.lastname: Irako
authors.forename: T
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: K
authors.initials: K
authors.lastname: Saotome
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology*; D002455:Cell Division; D005260:Female; D005870:Giant Cell Tumors / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D008297:Male; D009365:Neoplasm Regression, Spontaneous; D011379:Prognosis