[The effect of the inoculum concentration on the in vitro sensitivity of Pseudomonas aeruginosa].
Using a broth microtiter dilution method, the minimum inhibitory concentrations of antipseudomonal antibiotics were determined against 19 P. aeruginosa isolates. Two different concentration of inoculum, 10(5) and 10(8), were used to show the inoculum concentration effect of in vitro antibiotic susceptibility tests. On the basis of the MIC values and using Howard B.J. (1) breakpoints, the effect of inoculum density was most prominent for amikacin and aztreonam, intermediate for mezlocillin, ticarcillin, piperacillin, cefotaxime, cefoperazone, netilmicin, tobramycin, gentamicin, and least apparent for ciprofloxacin and carbenicillin respectively.
Zarakolu
P
P
Refik Saydam Hifzissihha Merkez Başkanliği, Mikrobiyoloji ve Klinik Mikrobiyoloji Bölümü.
Cöplü
N
N
Güvener
E
E
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015169:Colony Count, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000254:growth & development
D000900:Anti-Bacterial Agents
Pseudomonas aeruginosa'ya karşi in vitro antibiyotik hassasiyet çalişmalarinda inokulum konsantrastrasyonunun etkisi.