[Immunohistochemical study of hepatitis B surface and core antigens in HBsAg seronegative and seropositive organ and tissue donors].
Hepatitis B virus antigen screening in the liver of organ and tissue donors was performed. The results of a 4-year period are compared with the serological findings. The immunohistochemical and serological data altered in two out of 15 organ donors. HBV antigen could be detected in the liver, however the serological examination was negative in these persons. The author emphasize the risk of a possible hepatitis B virus transmission through organ and tissue transplantation. A detailed examination of the donors is suggested.
Rékó
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Országos Traumatológiai Intézet, Pathologiai Osztály, Budapest.
D006509:Hepatitis B / Q000635:transmission; D006512:Hepatitis B Core Antigens / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006801:Humans; D007150:Immunohistochemistry; D008099:Liver / Q000276:immunology*; D016377:Organ Transplantation; D012307:Risk Factors; D014019:Tissue Donors; D016378:Tissue Transplantation
D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens
Hepatitis B surface és core antigén immunhisztokémiai vizsgálata HBsAg szeronegatív és szeropozitív szerv- és szövetdonorokon.