title: [Carbamazepine cardiotoxicity in acute poisoning].
abstract: Manifestations of cardiotoxicity in 9 patients with acute carabamazepine poisoning treated at the Clinic of Toxicology and Clinical Pharmacology of the M.M.A. in 1989 are reported. In all patients together with symptoms and signs characteristic for acute carbamezapine poisoning, there have been also present disorders of the cardiovascular system. The most common clinical signs of cardiotoxicity have been tachycardia and hypotension, and electrocardiographic, ventricular extrasystoles and repolarization disorders. Cardiotoxic manifestations in two cases have been the vital threat for the patients. After application of nonspecific and symptomatic therapy, clinical and electrocardiographic signs of cardiotoxicity were withdrawn, that is, heart sequeles were not recorded.
authors.forename: V
authors.initials: V
authors.lastname: Todorović
authors.forename: S
authors.initials: S
authors.lastname: Randelović
authors.forename: D
authors.initials: D
authors.lastname: Joksović
authors.forename: J
authors.initials: J
authors.lastname: Jović-Stosić
authors.forename: S
authors.initials: S
authors.lastname: Vucinić
authors.forename: L
authors.initials: L
authors.lastname: Glisović
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D002220:Carbamazepine / Q000506:poisoning*; D005260:Female; D006321:Heart / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000503:physiopathology
chemical_list: D002220:Carbamazepine
vernacular_title: Kardiotoksicnost karbamazepina u akutnim trovanjima.