title: [Changes in left ventricular diastolic function and in tolerance to physical loading under the influence of finoptin in stenocardia patients].
abstract: A total of 45 patients aged 53.6 +/- 6.1 years who had Functional Class II-IV angina pectoris were examined. In patients with stable angina and normal left ventricular diastolic pressure, a moderate antianginal effect of finoptin was shown to be associated with decreased myocardial afterload. The normalizing effects of finoptin on baseline left ventricular diastolic dysfunction along with lower myocardial afterload resulted in an increase in coronary reserve and a more pronounced antianginal effect.
authors.forename: M I
authors.initials: MI
authors.lastname: Lutaĭ
authors.forename: A N
authors.initials: AN
authors.lastname: Lomakovskiĭ
mesh_terms: D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D003971:Diastole / Q000187:drug effects*; D004341:Drug Evaluation; D017079:Exercise Tolerance / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D016277:Ventricular Function, Left / Q000187:drug effects*; D014700:Verapamil / Q000627:therapeutic use*
chemical_list: D014700:Verapamil
vernacular_title: Izmenenie diastolicheskoĭ funktsii levogo zheludochka i tolerantnosti k fizicheskoĭ nagruzke pod vliianiem finoptina u bol'nykh stenokardieĭ.