Analysis of serotype-specific antibodies to Trichosporon cutaneum types I and II in patients with summer-type hypersensitivity pneumonitis with monoclonal antibodies to serotype-related polysaccharide antigens.
Summer-type hypersensitivity pneumonitis is the most prevalent type of hypersensitivity pneumonitis in Japan. We constructed a sandwich enzyme-linked immunosorbent assay system for diagnosis of summer-type hypersensitivity pneumonitis in which monoclonal antibodies were used to bind serotype-related polysaccharides to plastic plates, and this system was proven to have sufficient sensitivity and specificity.
Mizobe
T
T
Department of Immunology, Kumamoto University School of Medicine, Honjo, Japan.
Yamasaki
H
H
Doi
K
K
Ando
M
M
Onoue
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D000908:Antibodies, Fungal / Q000097:blood*; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D000946:Antigens, Fungal; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods / Q000706:statistics & numerical data; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides / Q000276:immunology; D012680:Sensitivity and Specificity; D012703:Serotyping; D014250:Trichosporon / Q000145:classification / Q000276:immunology*
D000908:Antibodies, Fungal; D000911:Antibodies, Monoclonal; D000946:Antigens, Fungal; D011134:Polysaccharides