title: Smooth pursuit eye movements and saccadic eye movements in patients with delusional disorder.
abstract: OBJECTIVE
  This study used eye movement tests to examine whether frontal lobe dysfunction is present in delusional disorder.
  
  
  METHODS
  Smooth pursuit and voluntary saccadic eye movements of 15 delusional patients, 40 schizophrenic patients, and 40 normal subjects were recorded and analyzed statistically.
  
  
  RESULTS
  The schizophrenic patients differed significantly from the normal subjects in some smooth pursuit eye movement characteristics, whereas both the schizophrenic and the delusional patients showed more saccades than the normal subjects during the smooth pursuit test. The delusional patients and normal subjects differed significantly in some voluntary saccadic eye movement characteristics.
  
  
  CONCLUSIONS
  The data support the idea of a biological dysfunction in eye tracking in delusional disorder.
authors.affiliation: Department of Biomedical and Technological Sciences, University of Milan Medical School, Italy.
authors.forename: O
authors.initials: O
authors.lastname: Gambini
authors.forename: C
authors.initials: C
authors.lastname: Colombo
authors.forename: R
authors.initials: R
authors.lastname: Cavallaro
authors.forename: S
authors.initials: S
authors.lastname: Scarone
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003702:Delusions / Q000175:diagnosis / Q000503:physiopathology*; D003937:Diagnosis, Differential; D005163:Factor Analysis, Statistical; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D011698:Pursuit, Smooth / Q000502:physiology*; D011930:Reaction Time; D012438:Saccades / Q000502:physiology*; D012559:Schizophrenia / Q000175:diagnosis / Q000503:physiopathology*; D012565:Schizophrenic Psychology