Adenosquamous carcinoma of the duodenum. An immunohistochemical study.
A rare adenosquamous carcinoma of the duodenum occurred in an 84-year-old woman. Histologically the neoplasm showed evidence of glandular and squamous differentiation, and both components showed malignant characteristics. Intermediate elements sharing squamous and glandular features, were found and were immunoreactive for carcinoembryonic antigen, epithelial membrane antigen and cytokeratins of both low and high molecular weight. A review of the literature and discussion about the histogenesis is included.
de la Cruz
A
A
Centro Oncologico de Galicia, Servicio de Anatomia Patologica, La Couruña, Spain.
de la Cruz
E
E
Sanchez
M J
MJ
Ortiz
S
S
Lobato
A
A
Merino
E
E
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D011859:Radiography