Diagnostic utility of immunohistochemical techniques in intramedullary Schwann-cell tumours.
Histopathologic features in two intramedullary schwann-cell tumours, closely resembled with those of fibrillary astrocytoma and could not be differentiated from each other by the conventional histochemical stains. However application of tumour markers-Glial fibrillary acidic protein (GFAP) and S-100 protein were found to be useful in differentiating these two tumours and thus helped in making an accurate histopathological diagnosis in these two patients.
Radhakrishnan
V V
VV
Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum.
Saraswathy
A
A
Radhakrishnan
N S
NS
Rout
D
D
D001254:Astrocytoma / Q000175:diagnosis; D014408:Biomarkers, Tumor / Q000032:analysis*; D003937:Diagnosis, Differential; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000737:chemistry / Q000150:complications / Q000175:diagnosis*; D009418:S100 Proteins / Q000032:analysis*; D013117:Spinal Cord Compression / Q000209:etiology; D013120:Spinal Cord Neoplasms / Q000737:chemistry / Q000175:diagnosis*
D014408:Biomarkers, Tumor; D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins