title: Management of meningococcal infections.
abstract: The last 5 years has seen an increase in the number of cases of meningococcal infection. Despite the availability of highly active antibiotics, the mortality from this infection remains at 10%, rising to 40% in patients presenting in severe shock. Here we describe the spectrum and pathophysiology of meningococcal infections, and the most important aspects of treatment and management.
authors.affiliation: Department of Paediatrics, St Mary's Hospital Medical School, London.
authors.forename: N J
authors.initials: NJ
authors.lastname: Klein
authors.forename: R S
authors.initials: RS
authors.lastname: Heyderman
authors.forename: M
authors.initials: M
authors.lastname: Levin
mesh_terms: D016470:Bacteremia / Q000382:microbiology; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000628:therapy; D005440:Fluid Therapy; D006801:Humans; D008589:Meningococcal Infections / Q000628:therapy; D009345:Neisseria meningitidis / Q000502:physiology; D010406:Penicillins / Q000627:therapeutic use; D012772:Shock, Septic / Q000382:microbiology
chemical_list: D010406:Penicillins