Minimal change nephropathy in the west of Scotland: a review of sixty-four patients.
Sixty-four patients with a histological diagnosis of minimal change nephropathy have been followed for a median of 110 months. Patients transferred from paediatric units (11%) had a worse prognosis in that all became frequent relapsers. Patients who relapsed within three months or who went on to become frequent relapsers had a higher 24 hour urine protein excretion at presentation than patients who did not relapse. After fifteen months of remission relapse was rare; 97% of those who relapsed did so within 36 months. Patients who have been off steroids and proteinuria free for 36 months might therefore be considered cured.
Shilliday
I R
IR
Renal Unit, Royal Infirmary, Glasgow.
Simpson
K
K
Jackson
R
R
McLay
A L
AL
Boulton-Jones
M
M
D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D009402:Nephrosis, Lipoid / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D011507:Proteinuria / Q000209:etiology; D012008:Recurrence; D012606:Scotland / Q000453:epidemiology
D003520:Cyclophosphamide; D011239:Prednisolone