[An experimental animal model for inducing fetal distress during pregnancy].
In order to try to understand and treat efficiently pathology in the human pregnant woman the authors have carried out experimental work on animals. Twenty four pregnant ewes with a single fetus were operated on in the last trimester of pregnancy. Fetal distress was provoked by injecting microspheres into the aorta beneath the renal arteries via the femoral route. The first results in terms of survival, by chemical and Doppler measurements were very encouraging. The operation itself was not a significantly disturbing factor, but the injection of microspheres did cause fetal distress. This experiment should be continued.
Gaucherand
P
P
Service de Gynécologie-Obstétrique, Hôpital de la Croix-Rousse, Lyon.
Franck
M
M
Tran-Minh
V
V
Parisot
P
P
D000208:Acute Disease; D000818:Animals; D001012:Aorta, Abdominal; D001783:Blood Flow Velocity; D001784:Blood Gas Analysis; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D002908:Chronic Disease; D004195:Disease Models, Animal; D004617:Embolism / Q000097:blood / Q000000981:diagnostic imaging / Q000401:mortality / Q000503:physiopathology; D005069:Evaluation Studies as Topic; D005260:Female; D005316:Fetal Distress / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology* / Q000401:mortality / Q000503:physiopathology; D007269:Injections, Intra-Arterial; D008863:Microspheres; D011247:Pregnancy; D011256:Pregnancy Outcome; D012756:Sheep; D015996:Survival Rate; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology
Modèle animal expérimental d'induction de la souffrance foetale pendant la grossesse.