Potassium replacement associated with the development of tetany in a patient with hypomagnesaemia.
A case of hypomagnesaemia secondary to cisplatin therapy and diarrhoea had concomitant hypokalaemia. Increasing the serum potassium level from 2.8 to 3.4 mmol/litre by potassium supplementation induced tetany. Hypokalaemia in the face of hypomagnesaemia may have a membrane-stabilizing effect and preserve excitability.
Cohen
L
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Department of Medicine B, Lady Davis Carmel Hospital, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
D000328:Adult; D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced* / Q000188:drug therapy*; D008275:Magnesium Deficiency / Q000139:chemically induced*; D008297:Male; D011188:Potassium / Q000008:administration & dosage / Q000009:adverse effects*; D013736:Testicular Neoplasms / Q000188:drug therapy; D013746:Tetany / Q000139:chemically induced*
D002945:Cisplatin; D011188:Potassium