The reversal of multidrug resistance in cancer (review).
A brief review of the "state of the art" (1992) knowledge concerning various strategies and tactics to overcome multidrug resistance is presented. Multidrug resistance remains the main obstacle to long-term successful cancer chemotherapy; its prevention or elimination is probably one of the most promising avenues in cancer research.
Kellen
J A
JA
Department of Clinical Biochemistry, Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada.
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004351:Drug Resistance; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents