title: Allograft in the treatment of benign cystic lesions of bone.
abstract: Seventeen patients with benign cystic osseous lesions were treated by curettage and grafting using allogenic decalcified bone. Human bones were partially decalcified using 0.6 N HCl and preserved in 90% ethanol in a deep freezer at -16 degrees C. The cystic lesions were: 5 cases of fibrous dysplasia, 4 aneurysmal bone cysts, 3 simple bone cysts, 2 giant-cell tumours, 1 chondromyxoid fibroma, 1 non-ossifying fibroma and 1 fibrous cortical defect. The bones involved were: femur, tibia, humerus, fibula and calcaneum. Infection was a complication in three patients. In two of these it did not interfere with healing, but in one it persisted for more than 1 year with partial resorption of the graft. The time to adequate incorporation of the graft varied from 6 to 9 months in children and 9 to 15 months in adults. The overall response compares favourably with that to allograft from more sophisticated bone banks.
authors.affiliation: Department of Orthopaedics, University College of Medical Sciences and G.T.B. Hospital, Delhi, India.
authors.forename: A
authors.initials: A
authors.lastname: Sethi
authors.forename: K
authors.initials: K
authors.lastname: Agarwal
authors.forename: S
authors.initials: S
authors.lastname: Sethi
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.forename: S K
authors.initials: SK
authors.lastname: Marya
authors.forename: S M
authors.initials: SM
authors.lastname: Tuli
mesh_terms: D000293:Adolescent; D000328:Adult; D001845:Bone Cysts / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005269:Femur / Q000601:surgery; D005357:Fibrous Dysplasia of Bone / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D006811:Humerus / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013977:Tibia / Q000601:surgery; D014945:Wound Healing