[The effect of antiparkinson preparations on the self-stimulation reaction of rabbits in a helium-oxygen environment under increased pressure].
The authors studied hypothalamic self-stimulation of 30 rabbits in hyperbaric heliox after intraperitoneal injections of L-DOPA, melanostatin, and cyclodol. The frequency of self-stimulation was decreased with 40 atm of heliox. After L-DOPA administration, a reduction of self-stimulation was twice less than that in heliox without pharmaceuticals.
Sledkov
A Iu
AIu
D000818:Animals; D000978:Antiparkinson Agents / Q000494:pharmacology*; D001273:Atmosphere Exposure Chambers; D001274:Atmospheric Pressure; D004242:Diving; D004305:Dose-Response Relationship, Drug; D004567:Electrodes, Implanted; D004780:Environment, Controlled; D006371:Helium; D008297:Male; D010100:Oxygen; D011817:Rabbits; D012653:Self Stimulation / Q000187:drug effects*
D000978:Antiparkinson Agents; D006371:Helium; C038949:heliox; D010100:Oxygen
Vliianie antiparkinsonicheskikh preparatov na reaktsiiu samostimuliatsii u krolikov v geliĭ-kislorodnoĭ srede pod povyshennym vliianiem.