title: RNA drug therapy acting via the 2-5A synthetase/RNase L pathway.
authors.affiliation: Department of Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
authors.forename: R J
authors.initials: RJ
authors.lastname: Suhadolnik
authors.forename: N L
authors.initials: NL
authors.lastname: Reichenbach
authors.forename: P M
authors.initials: PM
authors.lastname: Hitzges
authors.forename: D V
authors.initials: DV
authors.lastname: Ablashi
authors.forename: D R
authors.initials: DR
authors.lastname: Strayer
authors.forename: W A
authors.initials: WA
authors.lastname: Carter
mesh_terms: D015088:2',5'-Oligoadenylate Synthetase / Q000378:metabolism*; D004311:Double-Blind Method; D004722:Endoribonucleases / Q000378:metabolism*; D015673:Fatigue Syndrome, Chronic / Q000188:drug therapy* / Q000201:enzymology; D006801:Humans; D011070:Poly I-C / Q000627:therapeutic use*; D011072:Poly U / Q000627:therapeutic use*; D012330:RNA, Double-Stranded / Q000627:therapeutic use*
chemical_list: D012330:RNA, Double-Stranded; D011072:Poly U; C047490:poly(I).poly(c12,U); D015088:2',5'-Oligoadenylate Synthetase; D004722:Endoribonucleases; C031956:2-5A-dependent ribonuclease; D011070:Poly I-C