title: [Spontaneous coronary dissection. Apropos of 2 cases].
abstract: Spontaneous coronary dissection is a rare and still poorly understood pathological disease entity; the authors report two cases in which the diagnosis was reached in the context of incipient necrosis in young patients. A review of the literature reveals the main characteristics of this problem: the clinical aspect is generally that of acute coronary failure with the constitution of an infarction. The subjects are young with no risk factor but some cases of combination with a disease affecting the elastic tissue have been described. Female gender and the post-partum phase are promoting factors. Diagnosis was long established by means of autopsy but can now be based on coronary angiography. Histologically, the lesion is a hematoma which dissects the arterial wall between the internal two thirds and external third of the media. The main etiological hypothesis is acquired or congenital fragility of the media, which promotes the formation of a dissecting hematoma, however the triggering phenomenon remains poorly understood.
authors.affiliation: Service de Cardiologie, Hôpital du Bocage, CHU de Dijon.
authors.forename: M
authors.initials: M
authors.lastname: Cohen
authors.forename: Y
authors.initials: Y
authors.lastname: Cottin
authors.forename: P
authors.initials: P
authors.lastname: Morelon
authors.forename: F
authors.initials: F
authors.lastname: André
authors.forename: R
authors.initials: R
authors.lastname: Brenot
authors.forename: J E
authors.initials: JE
authors.lastname: Wolf
authors.forename: P
authors.initials: P
authors.lastname: Louis
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000175:diagnosis* / Q000209:etiology; D003323:Coronary Aneurysm / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male
vernacular_title: Dissection coronaire spontanée. A propos de deux cas.