title: Synergy characterization for Enterococcus faecalis strains displaying moderately high-level gentamicin and streptomycin resistance.
abstract: Synergy of 14 Enterococcus faecalis strains displaying moderately high-level aminoglycoside resistance (MICs, 500 and 256 to 1,000 micrograms/ml for gentamicin and streptomycin, respectively) was characterized by time-kill studies. All strains proved resistant to penicillin plus the respective aminoglycoside. Strains with moderately high-level aminoglycoside resistance should be considered to exhibit high-level resistance in severe infections.
authors.affiliation: Laboratorio de Bacteriología Clínica, Centro de Educación Médica e Investigaciones Clínicas, Buenos Aires, Argentina.
authors.forename: C E
authors.initials: CE
authors.lastname: Bantar
authors.forename: M
authors.initials: M
authors.lastname: Micucci
authors.forename: L
authors.initials: L
authors.lastname: Fernandez Canigia
authors.forename: J
authors.initials: J
authors.lastname: Smayevsky
authors.forename: H M
authors.initials: HM
authors.lastname: Bianchini
mesh_terms: D004352:Drug Resistance, Microbial; D004357:Drug Synergism; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000302:isolation & purification; D005839:Gentamicins / Q000008:administration & dosage / Q000494:pharmacology*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy; D006801:Humans; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D013307:Streptomycin / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D005839:Gentamicins; D013307:Streptomycin