title: SHIN, a low frequency red cell antigen, found in two Japanese blood donors.
abstract: A low frequency red cell antigen, SHIN, was detected in two Japanese blood donors. Red cells of the first propositus reacted, in pretransfusion tests, with the serum of a previously untransfused male patient. The second propositus was disclosed when anti-SHIN was used to screen red cells from 3,000 random blood donors in Tokyo: a frequency of 0.03% in this population. Family studies showed SHIN to be inherited as an autosomal dominant character and not to be part of the MNS, FY, JK or P1 blood group systems. Anti-SHIN is not a common antibody in normal sera but was found in about 10% of multispecific sera used in investigation of low frequency antigens.
authors.affiliation: Department of Forensic Medicine, Tokyo Medical and Dental University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nakajima
authors.forename: H
authors.initials: H
authors.lastname: Satoh
authors.forename: F
authors.initials: F
authors.lastname: Komatsu
authors.forename: C A
authors.initials: CA
authors.lastname: Green
authors.forename: P
authors.initials: P
authors.lastname: Tippett
authors.forename: A
authors.initials: A
authors.lastname: Lubenko
mesh_terms: D044466:Asian People / Q000235:genetics; D001782:Blood Donors; D001789:Blood Group Antigens / Q000097:blood / Q000235:genetics* / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D005799:Genes, Dominant; D008040:Genetic Linkage; D006801:Humans; D016130:Immunophenotyping; D007564:Japan; D008297:Male; D008875:Middle Aged; D010375:Pedigree
chemical_list: D001789:Blood Group Antigens