Sulfoorientalols a, b, c, and d, four new biologically active sesquiterpenes from Alismatis rhizoma.
Four new sesquiterpenes, sulfoorientalols a, b, c, and d, having a sulfonic acid function were isolated from Chinese Alismatis Rhizoma. Their structures were determined on the basis of chemical and physicochemical evidence. Sulfoorientalols inhibited the contraction of isolated bladder smooth muscle induced by carbachol.
Yoshikawa
M
M
Kyoto Pharmaceutical University, Japan.
Fukuda
Y
Y
Hatakeyama
S
S
Tanaka
N
N
Matsuda
H
H
Yamahara
J
J
Murakami
N
N
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes