A comparison of the in vitro postantibiotic effect of meropenem and imipenem versus selected enterobacteriaceae and other pathogens.
The in vitro postantibiotic effect (PAE) of meropenem (Merrem or SM-7338) and imipenem was determined by using 12 strains of clinically important pathogens. A PAE of > or = 1/2 h duration was observed more frequently with strains tested against meropenem than with imipenem.
Nadler
H L
HL
Zeneca Pharmaceuticals Group, Wilmington, Delaware.
Sheikh
W
W
D039903:Actinobacteria / Q000187:drug effects; D004755:Enterobacteriaceae / Q000187:drug effects*; D013293:Enterococcus faecalis / Q000187:drug effects; D015378:Imipenem / Q000494:pharmacology*; D000077731:Meropenem; D008826:Microbial Sensitivity Tests; D013845:Thienamycins / Q000494:pharmacology*; D013997:Time Factors
D013845:Thienamycins; D015378:Imipenem; D000077731:Meropenem