Identification and characterization of surface proteins from Staphylococcus saprophyticus.
Staphylococcus saprophyticus, a well known cause of urinary tract infections, possesses several properties, such as hemagglutination of sheep erythrocytes, adherence to various cell types and production of urease, which may be virulence factors. In this contribution, we summarise the present knowledge about recently discovered surface proteins of Staphylococcus saprophyticus, a 95 kDa surface-associated protein (Ssp) and the hemagglutinin, a 160 kDa surface polypeptide. We describe culture conditions conducive to production of these surface proteins and discuss the molecular and clinical implications of our findings.
Gatermann
S
S
Institut für Medizinische Mikrobiologie, Medizinischen Universität zu Lübeck, Germany.
Meyer
H G
HG
Marre
R
R
Wanner
G
G
D001422:Bacterial Adhesion / Q000502:physiology; D001426:Bacterial Proteins / Q000302:isolation & purification / Q000378:metabolism*; D001431:Bacteriological Techniques; D002460:Cell Line; D006384:Hemagglutination / Q000502:physiology; D006801:Humans; D008565:Membrane Proteins / Q000302:isolation & purification / Q000378:metabolism; D008854:Microscopy, Electron; D008970:Molecular Weight; D013203:Staphylococcal Infections / Q000209:etiology; D013210:Staphylococcus / Q000378:metabolism* / Q000472:pathogenicity / Q000648:ultrastructure; D014552:Urinary Tract Infections / Q000209:etiology; D014774:Virulence
D001426:Bacterial Proteins; D008565:Membrane Proteins