Peptidomimetic HIV protease inhibitors: phosphate prodrugs with improved biological activities.
Chong
K T
KT
Cancer & Infectious Diseases Research, Upjohn Company, Kalamazoo, Michigan 49001.
Ruwart
M J
MJ
Hinshaw
R R
RR
Wilkinson
K F
KF
Rush
B D
BD
Yancey
M F
MF
Strohbach
J W
JW
Thaisrivongs
S
S
D000818:Animals; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology; D017320:HIV Protease Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D006207:Half-Life; D006801:Humans; D008297:Male; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology; D011355:Prodrugs / Q000138:chemical synthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013329:Structure-Activity Relationship
D000998:Antiviral Agents; D017320:HIV Protease Inhibitors; D009943:Organophosphorus Compounds; D011355:Prodrugs