title: The clinical and radiological evaluation of primary brain neoplasms in children, Part II: Radiological evaluation.
abstract: Data collected over the past 8 years on the radiological appearance of common pediatric primary brain neoplasms are presented. An emphasis is placed on the newer radiological imaging modality of magnetic resonance imaging (MRI). Part I of this article emphasized the clinical evaluation of these brain neoplasms. Three hundred eighty-five children with known brain neoplasms ranging in age from newborn to 18 years were evaluated with one or all of the following radiological modalities: MRI, computed tomography (CT), water-soluble myelography (WSM), WSM with CT, and angiography. Contrast-enhanced MRI and CT scans both were accurate in delineating these brain neoplasms although MRI provided better resolution and delineation than CT. Angiography provided information on the vascularity of the neoplasms and their relationship to prominent arterial and venous structures. Water-soluble myelography with CT and gadolinium-enhanced MRI of the spine were equally accurate in demonstrating metastatic spread to the spinal canal and spinal cord. Magnetic resonance imaging with gadolinium was more accurate than CT with contrast in demonstrating recurrent or residual neoplasm at the operative site and metastatic spread to the brain. Magnetic resonance imaging with gadolinium is the best radiological modality to fully evaluate pediatric brain neoplasms.
authors.affiliation: Department of Radiology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614.
authors.forename: E D
authors.initials: ED
authors.lastname: Allen
authors.forename: S E
authors.initials: SE
authors.lastname: Byrd
authors.forename: C F
authors.initials: CF
authors.lastname: Darling
authors.forename: T
authors.initials: T
authors.lastname: Tomita
authors.forename: M A
authors.initials: MA
authors.lastname: Wilczynski
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis*; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D005682:Gadolinium; D006801:Humans; D007223:Infant; D015192:Infratentorial Neoplasms / Q000175:diagnosis; D007472:Iohexol; D007483:Iothalamic Acid; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D009192:Myelography; D015173:Supratentorial Neoplasms / Q000175:diagnosis; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods
chemical_list: D007483:Iothalamic Acid; D007472:Iohexol; D005682:Gadolinium