title: Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a.
abstract: Expression of pathogenesis-related protein 1a (PR-1a), a protein of unknown biochemical function, is induced to high levels in tobacco in response to pathogen infection. The induction of PR-1a expression is tightly correlated with the onset of systemic acquired resistance (SAR), a defense response effective against a variety of fungal, viral, and bacterial pathogens. While PR-1a has been postulated to be involved in SAR, and is the most highly expressed of the PR proteins, evidence for its role is lacking. In this report, we demonstrate that constitutive high-level expression of PR-1a in transgenic tobacco results in tolerance to infection by two oomycete pathogens, Peronospora tabacina and Phytophthora parasitica var. nicotianae.
authors.affiliation: Calgene, Inc., Davis, CA 95616.
authors.forename: D
authors.initials: D
authors.lastname: Alexander
authors.forename: R M
authors.initials: RM
authors.lastname: Goodman
authors.forename: M
authors.initials: M
authors.lastname: Gut-Rella
authors.forename: C
authors.initials: C
authors.lastname: Glascock
authors.forename: K
authors.initials: K
authors.lastname: Weymann
authors.forename: L
authors.initials: L
authors.lastname: Friedrich
authors.forename: D
authors.initials: D
authors.lastname: Maddox
authors.forename: P
authors.initials: P
authors.lastname: Ahl-Goy
authors.forename: T
authors.initials: T
authors.lastname: Luntz
authors.forename: E
authors.initials: E
authors.lastname: Ward
mesh_terms: D009868:Oomycetes / Q000472:pathogenicity*; D010935:Plant Diseases; D010940:Plant Proteins / Q000235:genetics*; D030821:Plants, Genetically Modified; D010947:Plants, Toxic; D014026:Nicotiana
chemical_list: D010940:Plant Proteins; C053376:pathogenesis-related proteins, plant