title: Comprehensive breast diagnosis.
abstract: Applying a comprehensive diagnostic approach to breast pathology (clinical information, physical exam, state of the art mammography complemented by ultrasonography) 36,396 patients were evaluated. 462 malignancies (40%) were found. 81.2% of carcinomas were clinically occult. 45.2% of the non-palpable lesions were 1 cm or smaller. The yield of carcinomas was 1 every 2.7 biopsies. The preoperative diagnosis of presumptive extensive intraductal component was 85% correct. This information helps to define the excisional limits and upon pathological confirmation select the appropriate surgical therapy: lympectomy vs. mastectomy.
authors.affiliation: Comprehensive Breast Center, Mount Sinai Medical Center, Miami Beach, Florida.
authors.forename: R H
authors.initials: RH
authors.lastname: Matallana
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008327:Mammography / Q000191:economics; D008403:Mass Screening / Q000191:economics / Q000379:methods; D015412:Mastectomy, Segmental; D016217:Ultrasonography, Mammary; D014481:United States / Q000453:epidemiology