Short-term oral sensory deprivation: possible cause of binge eating in sham-feeding dogs.
Six mongrel dogs (18-20 kg) were prepared with gastric and esophageal fistulas. All dogs were studied under four experimental conditions. In conditions 1 and 3 the dogs were allowed to sham feed either a high-palatable or low-palatable meal on days 1-5 followed by a sham feed of a high-palatable or low-palatable meal on day 6. In conditions 2 and 4 the dogs were not sham fed (oral sensory deprived) on days 1-5 but were allowed to sham feed either a high-palatable or low-palatable meal on day 6. Total caloric requirement during each 6-day study was given by infusion of a liquid diet (Isocal) through the gastric fistula following the experiment. In condition 4, dogs deprived of oral sensation on days 1-5, significantly overconsumed their low-palatable meal on day 6. In condition 2, dogs deprived of oral sensation on days 1-5 also overconsumed their high-palatable meal on day 6, although this did not reach statistical significance. Dogs that received oral stimulation days 1-5 (conditions 1 and 3) did not overconsume their high- and low-palatable meals on day 6, suggesting that binge eating following short-term oral deprivation may be avoided if the diet provides adequate oral sensory stimulation. Body weights were well maintained throughout each study period and no changes were observed.
Lawson
D C
DC
Department of Surgery, Duke University Medical Center, Durham, NC 27710.
Schiffman
S S
SS
Pappas
T N
TN
D000818:Animals; D004285:Dogs; D004435:Eating / Q000502:physiology*; D002149:Energy Intake / Q000502:physiology; D004750:Enteral Nutrition; D005744:Gastric Acid / Q000378:metabolism; D010191:Pancreatic Polypeptide / Q000097:blood; D012528:Satiety Response / Q000502:physiology*; D012683:Sensory Deprivation / Q000502:physiology*; D013649:Taste / Q000502:physiology*
D010191:Pancreatic Polypeptide