title: T cell receptor variable region gene usage in juvenile chronic arthritis.
abstract: Up to now the data regarding T cell receptor V-gene usage by juvenile chronic arthritis synovial T lymphocytes has been conflicting. Thus, some studies claim that locally in the diseased joint there is an oligoclonal expansion of T cells with restricted T cell receptor variable region gene usage while others have found V-gene usage in the joint compatible with a polyclonal expansion of the T cells.
authors.affiliation: Oslo Sanitetsforenings Rheumatism Hospital, Norway.
authors.forename: O
authors.initials: O
authors.lastname: Førre
authors.forename: M
authors.initials: M
authors.lastname: Sioud
mesh_terms: D001171:Arthritis, Juvenile / Q000209:etiology / Q000235:genetics*; D005796:Genes; D006801:Humans; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D011948:Receptors, Antigen, T-Cell / Q000235:genetics*
chemical_list: D007135:Immunoglobulin Variable Region; D011948:Receptors, Antigen, T-Cell