title: [Barrett++ esophagus in children. Presentation of 12 cases].
abstract: This paper describes 12 cases of Barrett's oesophagus selected out of a population of 364 refluxing children studied from 1986 to 1990. Their mean age was 14, seven were cared for in special institutions for brain damaged and 2 had been operated upon for oesophageal atresia at birth. Excessive acid exposure was documented in 8/10 patient studied and simultaneous gastric and oesophageal pH-monitoring demonstrated massive duodeno-gastric alkaline reflux in 3. Histological studies revealed that columnar-lined epithelium was of fundic type in 2 cases, of junctional type in 7 and of specialized type in three. Helicobacter pylori was found in the mucosa of 8 patients. The present series confirms that BE should be looked for endoscopically in children with GER and provides further evidence of the long duration of GER disease and the excessive acid-alkaline chemical exposure of the oesophageal lining in the pathogenesis of mucosal changes.
authors.affiliation: Servicio de Cirugía Pediátrica, Universidad del País Vasco, Hospital N.S. Aránzazu, San Sebastián.
authors.forename: I
authors.initials: I
authors.lastname: Eizaguirre
authors.forename: J A
authors.initials: JA
authors.lastname: Tovar
authors.forename: L
authors.initials: L
authors.lastname: Gorostiaga
authors.forename: J
authors.initials: J
authors.lastname: Echeverry
authors.forename: J
authors.initials: J
authors.lastname: Torrado
mesh_terms: D000293:Adolescent; D000328:Adult; D001471:Barrett Esophagus / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005764:Gastroesophageal Reflux / Q000209:etiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry
vernacular_title: Esófago de Barrett en niños. Presentación de doce casos.