title: Histocompatibility antigens in Egyptians with cutaneous leishmaniasis: a preliminary study.
abstract: The frequency of human leucocytic antigens (HLA) were studied in 27 patients with cutaneous leishmaniasis to evaluate the role of HLA antigens as genetic markers in the pathogenesis of this protozoal skin infection. A significant statistical association was observed between HLA-A11, -B5 and -B7 antigens and diffuse cutaneous leishmaniasis. In conclusion, study of immune response genes could be of value to understand the pathogenic mechanisms responsible for cutaneous leishmaniasis.
authors.affiliation: Department of Dermatology, Mansoura Faculty of Medicine, Egypt.
authors.forename: M H
authors.initials: MH
authors.lastname: el-Mogy
authors.forename: I A
authors.initials: IA
authors.lastname: Abdel-Hamid
authors.forename: M M
authors.initials: MM
authors.lastname: Abdel-Razic
authors.forename: R A
authors.initials: RA
authors.lastname: Rizk
authors.forename: S A
authors.initials: SA
authors.lastname: Romia
mesh_terms: D000328:Adult; D004534:Egypt / Q000453:epidemiology; D005819:Genetic Markers; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D015234:HLA-A Antigens / Q000032:analysis / Q000235:genetics; D059870:HLA-A11 Antigen; D015235:HLA-B Antigens / Q000032:analysis / Q000235:genetics; D015793:HLA-B7 Antigen / Q000032:analysis / Q000235:genetics; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology / Q000209:etiology / Q000276:immunology*; D008297:Male
chemical_list: D005819:Genetic Markers; D006680:HLA Antigens; D015234:HLA-A Antigens; D059870:HLA-A11 Antigen; D015235:HLA-B Antigens; C035270:HLA-B5 antigen; D015793:HLA-B7 Antigen