Autism and hypomelanosis of Ito in twins.
A pair of monozygotic and a pair of dizygotic twins with autism and hypomelanosis of Ito skin-abnormalities are described. These observations are further evidence of the frequent association between these two conditions, already demonstrated in the literature, and suggest a possibly higher incidence of single gene associations among cases of autism with known genetic basis.
Zappella
M
M
Department of Child Neuropsychiatry, USL 30, Siena, Italy.
D000293:Adolescent; D001321:Autistic Disorder / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D003337:Corpus Callosum / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D007621:Karyotyping; D008279:Magnetic Resonance Imaging; D008297:Male; D008550:Melatonin / Q000032:analysis* / Q000378:metabolism; D008659:Metabolic Diseases / Q000150:complications / Q000503:physiopathology; D010859:Pigmentation Disorders / Q000150:complications / Q000503:physiopathology*; D011859:Radiography; D014430:Twins, Monozygotic
D008550:Melatonin