title: Differential neural activity in the human temporal lobe evoked by faces of family members and friends.
abstract: In 6 patients, depth electrodes revealed differential evoked responses to familiar versus novel faces. These differential responses were obtained in the amygdala, hippocampus, and temporal neocortex but not in the dorsolateral frontal or cingulate cortex. The limbic and temporal structures that differentiated novel from familiar faces did not respond differentially to variations in luminance. Limbic structures and temporal cortex thus appear to participate in face recognition and in encoding the familiarity of visual experiences.
authors.affiliation: Department of Neurology, Ludwig-Maximilian University, Munich, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Seeck
authors.forename: N
authors.initials: N
authors.lastname: Mainwaring
authors.forename: J
authors.initials: J
authors.lastname: Ives
authors.forename: H
authors.initials: H
authors.lastname: Blume
authors.forename: D
authors.initials: D
authors.lastname: Dubuisson
authors.forename: R
authors.initials: R
authors.lastname: Cosgrove
authors.forename: M M
authors.initials: MM
authors.lastname: Mesulam
authors.forename: D L
authors.initials: DL
authors.lastname: Schomer
mesh_terms: D000328:Adult; D000679:Amygdala / Q000503:physiopathology*; D004292:Dominance, Cerebral; D017029:Epilepsy, Complex Partial / Q000473:pathology / Q000503:physiopathology*; D005074:Evoked Potentials, Visual; D005260:Female; D007839:Functional Laterality; D006624:Hippocampus / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009474:Neurons / Q000473:pathology / Q000502:physiology*; D009928:Organ Specificity; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology*