[The pharmacokinetics and pharmacodynamics of trental in pregnant women with chronic placental insufficiency].
Examining the relationship between the pharmacokinetic characteristics of trental, its effect on platelet aggregation and adverse effects in pregnant females with chronic placental failure has allowed the optimal dosage regimen to be recommended in the third trimester in this abnormality. Its daily dose was found to be 400 mg (100 mg x 4).
Zherdev
V P
VP
Boĭko
S S
SS
Vikhliaeva
E M
EM
Supriaga
O M
OM
D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D010431:Pentoxifylline / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000494:pharmacology*; D010927:Placental Insufficiency / Q000097:blood / Q000188:drug therapy*; D010974:Platelet Aggregation / Q000187:drug effects; D011247:Pregnancy; D011263:Pregnancy Trimester, Third
D010431:Pentoxifylline
Farmakokinetika i farmakodinamika trentala u beremennykh s khronicheskoĭ platsentarnoĭ nedostatochnost'iu.