[In vitro susceptibility to cefoperazone and sulbactam/cefoperazone combination of bacterial strains isolated from various patient materials].
Susceptibility of 110 bacterial strains isolated from clinical materials to Cefoperazone (CPZ) and Sulbactam/Cefoperazone (SBT/CPZ) combination was investigated and every strain was examined for beta-lactamase activity. Total beta-lactamase positivity rate was 40.9%. Antibacterial activity of SBT/CPZ combination was found to be higher than CPZ alone, especially on beta-lactamase producing bacteria.
Aksoy
A M
AM
Ankara Universitesi, Tip Fakültesi Mikrobiyoloji Anabilim Dali.
Ozsan
M
M
Ural
O
O
Ekmen
H
H
D001419:Bacteria / Q000187:drug effects* / Q000201:enzymology; D002438:Cefoperazone / Q000494:pharmacology*; D004338:Drug Combinations; D006801:Humans; D008826:Microbial Sensitivity Tests; D013407:Sulbactam / Q000494:pharmacology*; D001618:beta-Lactamases / Q000096:biosynthesis
D004338:Drug Combinations; D002438:Cefoperazone; D001618:beta-Lactamases; D013407:Sulbactam
Ceşitli hastalik materyallerinden izole edilen bakteri suşlarinin sefoperazon ve sulbaktam/sefoperazon kombinasyonuna karşi duyarliliklarinin in-vitro araştirilmasi.