title: IgD paraproteinemias.
abstract: In a series of 2038 paraproteinemic sera, 9 IgD paraproteins (0.44%) were found. Clinical diagnosis of all the 9 was multiple myeloma. One patient had an IgD-lambda plasmacytoma which developed into plasmocellular leukemia. Our series of IgD paraproteins consisted of 6 females and 3 males with a mean age of 58.5 years. The mean concentrations of IgD paraproteins were 6.7 +/- 4.26 g/l and the mean proteinuria was 5.1 +/- 4.76 g/24 h. Eight IgD paraproteins had light chains lambda and one had light chains kappa.
authors.affiliation: 2nd Department of Medicine, Charles University, Hradec Králové, Czechoslovakia.
authors.forename: M
authors.initials: M
authors.lastname: Tichý
authors.forename: F
authors.initials: F
authors.lastname: Matĕja
authors.forename: P
authors.initials: P
authors.lastname: Urban
authors.forename: M
authors.initials: M
authors.lastname: Matuska
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007072:Immunoglobulin D / Q000097:blood* / Q000652:urine; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains; D007136:Immunoglobulins / Q000097:blood; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000276:immunology*; D010265:Paraproteinemias / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D012737:Sex Factors; D001613:beta 2-Microglobulin / Q000032:analysis
chemical_list: D007072:Immunoglobulin D; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains; D007136:Immunoglobulins; D001613:beta 2-Microglobulin