[Expression of the Oct-2 protein during cell differentiation in vivo and in vitro].
The expression of an Oct-binding protein Oct-2 was studied during differentiation of three cell lines. Two inductors were used in our experiments: retinoic acid and DMSO. It was shown that all these cells have heterogeneous population of Oct-2 mRNA. Under differentiation the pattern of Oct-2 RNA and expression of active Oct-2 proteins was changed.
Pankratova
E V
EV
Sytina
E V
EV
Stepchenko
A G
AG
D000818:Animals; D015152:Blotting, Northern; D002454:Cell Differentiation / Q000187:drug effects / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D005314:Embryonic and Fetal Development / Q000235:genetics; D051379:Mice; D050813:Octamer Transcription Factor-2; D012333:RNA, Messenger / Q000378:metabolism; D014157:Transcription Factors; D014212:Tretinoin / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D004268:DNA-Binding Proteins; D050813:Octamer Transcription Factor-2; C489206:Pou2f2 protein, mouse; D012333:RNA, Messenger; D014157:Transcription Factors; D014212:Tretinoin; D004121:Dimethyl Sulfoxide
Ekspressiia belka Oct-2 v protsesse differentsirovki kletok in vivo i in vitro.