title: Accuracy of blood sampling through central venous lines in intensive-care unit patients.
abstract: OBJECTIVE
  In intensive-care unit (ICU) patients it is common practice to sample blood from central venous lines (CVL). This study was designed to answer the question on how much blood has to be aspirated through the CVL before the actual blood sample is taken to get accurate laboratory findings.
  
  
  METHODS
  Simultaneous blood samples from a peripheral vein (intraindividual control) and 5-ml portions from a CVL up to 25 ml were analyzed.
  
  
  METHODS
  5 patients of an internal ICU participated in the study.
  
  
  RESULTS
  For the analyzed 24 different parameters it could be shown that after aspirating 10 ml of blood, the results are comparable to analyses from peripheral vein samples.
  
  
  CONCLUSIONS
  Although blood sampling from a CVL--after aspiration of 10 ml blood--results in correct laboratory analyses, this procedure leads to a greater amount of blood loss and, hence, cannot be recommended in long-term ICU treatment.
authors.affiliation: Zentrum für Innere Medizin, Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main.
authors.forename: G
authors.initials: G
authors.lastname: Cieslinski
authors.forename: G
authors.initials: G
authors.lastname: Oremek
authors.forename: H
authors.initials: H
authors.lastname: Klepzig
mesh_terms: D000368:Aged; D001774:Blood Chemical Analysis; D001800:Blood Specimen Collection; D001810:Blood Volume / Q000502:physiology; D002405:Catheterization, Central Venous; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012016:Reference Values