title: Serum protein markers in the Piaroa Indians of Amazonia (Venezuela).
abstract: A sample of 121 Piaroa Indians from the Federal Amazonia Territory (Venezuela) was studied for the following serum protein polymorphisms: haptoglobin (HP), group-specific component subtypes (GC), orosomucoid (ORM), third component of complement (C3), transferrin C subtypes (TF) and alpha 1-antitrypsin subtypes (PI). The gene frequencies in the whole sample were: HP1 = 0.821; GC1S = 0.698; GC1F = 0.058; GC2 = 0.244; ORMS = 0.434; C3S = 0.699; C3F = 0.289; C3var = 0.012; TFC1 = 0.955; PIM1 = 0.467; PIM2 = 0.004; PIM3 = 0.529. The studied Piaroa sample came from three different communities: Gavilan, Paria and Alto Carinagua. The distribution of GC, C3 and HP polymorphisms was heterogeneous within the three groups. All the examined serum protein markers were polymorphic, in contrast to some enzymatic markers (ADA, DIA, 6PGD, AK) previously studied, which were shown to be monomorphic in the Piaroa. The results were compared with data from other populations living in the same territory.
authors.affiliation: Dipartimento Biologia Sperimentale, Università di Cagliari, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Marini
authors.forename: P
authors.initials: P
authors.lastname: Moral
authors.forename: I
authors.initials: I
authors.lastname: Petralanda
authors.forename: M
authors.initials: M
authors.lastname: Pacheco
authors.forename: T
authors.initials: T
authors.lastname: Sandiumenge
authors.forename: V
authors.initials: V
authors.lastname: Succa
authors.forename: S
authors.initials: S
authors.lastname: Vives
authors.forename: G
authors.initials: G
authors.lastname: Vona
mesh_terms: D000704:Analysis of Variance; D001798:Blood Proteins / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D008297:Male; D010641:Phenotype; D014687:Venezuela
chemical_list: D001798:Blood Proteins; D005819:Genetic Markers