title: In vivo quantitation of basal ganglia and thalamic degenerative changes in two temporal lobectomy patients with affective disorder.
abstract: The authors examined the brain magnetic resonance imaging scans of two epilepsy patients who had temporal lobectomies, one on the right and one on the left, with postoperative symptoms of affective disorders. Degenerative changes of ipsilateral thalamus and putamen after surgery, with coincident affective disorder, were noted. The authors discuss a possible relationship between postlobectomy degeneration and depression.
authors.affiliation: Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710.
authors.forename: I A
authors.initials: IA
authors.lastname: Parashos
authors.forename: S L
authors.initials: SL
authors.lastname: Oxley
authors.forename: O B
authors.initials: OB
authors.lastname: Boyko
authors.forename: K R
authors.initials: KR
authors.lastname: Krishnan
mesh_terms: D000328:Adult; D001479:Basal Ganglia / Q000503:physiopathology*; D001480:Basal Ganglia Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D001927:Brain Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008950:MMPI; D008279:Magnetic Resonance Imaging; D008297:Male; D019964:Mood Disorders / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D011183:Postoperative Complications; D011612:Psychosurgery / Q000009:adverse effects; D011699:Putamen / Q000503:physiopathology; D011859:Radiography; D015203:Reproducibility of Results; D013702:Temporal Lobe / Q000503:physiopathology* / Q000601:surgery*; D013788:Thalamus / Q000503:physiopathology*