[The efficacy of hydroxycinnamic acids in toxic lesions of the liver].
The albino rat experiments studied the pharmacological action of oxycinnamic acid derivatives in acute tetrachloromethane-induced hepatic dystrophy and combined CCl4-ethanol-induced hepatic lesion. The tested agents were found to produce cholagogic, membrane-protective, and antioxidative effects in these hepatic abnormalities, thus improving the functional (cholate- and glycogen-synthetic) parameters of the liver.
Drogovoz
S M
SM
Slyshkov
V V
VV
Sal'nikova
S I
SI
D000208:Acute Disease; D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000150:complications / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000209:etiology; D003373:Coumaric Acids / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D000431:Ethanol / Q000633:toxicity; D005419:Flavonoids / Q000627:therapeutic use; D008099:Liver / Q000187:drug effects; D010936:Plant Extracts / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D014810:Vitamin E / Q000627:therapeutic use
D003373:Coumaric Acids; D005419:Flavonoids; D010936:Plant Extracts; C061938:silibor; D014810:Vitamin E; D000431:Ethanol
Effektivnost' oksikorichnykh kislot pri toksicheskikh porazheniiakh pecheni.