Gaucher's disease associated with monoclonal gammapathy of undetermined significance: a case report.
We report a case of adult-type Gaucher's disease associated with monoclonal gammapathy of undetermined significance. Bone marrow infiltration by Gaucher's cells and spleen infiltration by Gaucher cells and plasma cells was observed on cytohistologic examination. Splenectomy induced complete recovery of cytopenias and a marked reduction of the monoclonal protein.
Airò
R
R
Servizio di Patologia, Ospedale Chiari-Rovato, USSL 34, Brescia, Italy.
Gabusi
G
G
Guindani
M
M
D000208:Acute Disease; D000740:Anemia / Q000209:etiology*; D001853:Bone Marrow / Q000473:pathology; D005776:Gaucher Disease / Q000097:blood / Q000150:complications* / Q000473:pathology; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D008297:Male; D008875:Middle Aged; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000097:blood / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D010266:Paraproteins / Q000032:analysis; D010950:Plasma Cells / Q000473:pathology; D013154:Spleen / Q000473:pathology; D013156:Splenectomy
D007145:Immunoglobulin kappa-Chains; D010266:Paraproteins