Regioselective and enantioselective epoxidation catalyzed by metalloporphyrins.
Recent progress in regioselective and enantioselective epoxidations catalyzed by metalloporphyrins is discussed here, with an explanation of the biomimetic antecedents of this area and its relevance to synthetic applications. Classification of the catalysts that have been studied allows useful conclusions to be drawn about the development of this field. In particular, both the most promising biomimetic and practical catalysts have arisen from systems that can be systematically modified by convenient synthetic methodology.
Collman
J P
JP
Department of Chemistry, Stanford University, CA 94305.
Zhang
X
X
Lee
V J
VJ
Uffelman
E S
ES
Brauman
J I
JI
D000475:Alkenes / Q000737:chemistry; D001665:Binding Sites; D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry / Q000378:metabolism*; D005029:Ethylenediamines / Q000737:chemistry; D006900:Hydroxylation; D008024:Ligands; D008665:Metalloporphyrins / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D000475:Alkenes; D004852:Epoxy Compounds; D005029:Ethylenediamines; D008024:Ligands; D008665:Metalloporphyrins; C011452:disalicylaldehyde ethylenediamine