Primary plasmacytoma of generalized lymph nodes: a long survivor.
Extramedullary plasmacytomas are occasionally seen in the course of multiple myeloma; however, primary plasmacytomas are unusual. Most of the primary plasmacytomas arise in the upper respiratory system, but a plasmacytoma of the lymph nodes is very rare. A case of a 56-year-old female with primary plasmacytoma in the lower mandibular, cervical, axillary, and para-aortic lymph nodes accompanied by IgA Kappa paraproteinemia is described. After ten courses of combination chemotherapy with cyclophosphamide and prednisolone, she obtained complete response. However, 6 years later, she had a relapse of plasmacytoma in the generalized lymph nodes. She received ten treatments of melphalan-prednisolone and again obtained complete response. She has remained well without chemotherapy or recurrent signs for 9 years. It is considered that conventional chemotherapy can be useful for primary plasmacytoma of generalized lymph nodes.
Matsushima
T
T
Third Department of Internal Medicine, College of Medical Care and Technology, Gunma University School of Medicine, Maebashi, Japan.
Murakami
H
H
Tamura
J
J
Sawamura
M
M
Naruse
T
T
Tsuchiya
J
J
D005260:Female; D006801:Humans; D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains; D008198:Lymph Nodes; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications; D010954:Plasmacytoma / Q000150:complications / Q000175:diagnosis* / Q000401:mortality; D013997:Time Factors
D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains