title: [Effects of 12wk-exercise walking on serum lipids, lipoproteins and apolipoproteins in middle aged women--does menopause status influence training effects?].
abstract: The present study examined the effects of 12wk-exercise walking on serum lipids in pre- and post-menopausal women, to elucidate the influence of menopausal status on the training effects. Twenty one premenopausal women (42.2 +/- 5.6 yr) and seventeen postmenopausal women (56.7 +/- 6.9 yr) participated in a 12 wk-walking program. Self-monitored exercise walking was performed 3 or 4 times per week in sessions of 45 minutes. Average intensity of the exercise was 57% HRmax in the premenopausal group (Pre-M) and 65.5% HRmax in the postmenopausal group (Post-M), respectively. After adjustment for age, baseline value of apolipoprotein AI (Apo AI) was significantly lower and total cholesterol (TC) and low density lipoprotein cholesterol (LDLC) were higher in Post-M than in Pre-M. After 12 weeks, percent body fat decreased significantly in both groups and BMI decreased in Pre-M. Physical fitness tended to increase only in Pre-M. The increase of high density lipoprotein cholesterol (HDLC) and the decrease of Apo AI, Apo B, TC/HDLC were significant in both groups. The decrease of TC, LDLC, Apo B and TG and the increase of HDLC were common changes in both groups, even after adjusting for baseline values, change in body composition, exercise intensity and total exercise time. Change volume of TG tended to be larger in Pre-M than in Post-M. Results of multiple regression analysis showed that the change in serum lipids, especially cholesterol, correlated to initial values, change in body composition and change in fitness, in Post-M but not in Pre-M.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Health Administration, Faculty of Medicine, University of Tokyo.
authors.forename: R
authors.initials: R
authors.lastname: Yanagibori
authors.forename: K
authors.initials: K
authors.lastname: Kawakubo
authors.forename: A
authors.initials: A
authors.lastname: Gunji
authors.forename: K
authors.initials: K
authors.lastname: Aoki
authors.forename: M
authors.initials: M
authors.lastname: Miyashita
mesh_terms: D000328:Adult; D001059:Apoproteins / Q000097:blood*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008593:Menopause / Q000502:physiology*; D008875:Middle Aged; D012044:Regression Analysis; D013997:Time Factors; D016138:Walking / Q000502:physiology*
chemical_list: D001059:Apoproteins; D008055:Lipids