Activity of PDGF (A) gene in the human cell line derived from a renal carcinoma metastasis.
PDGF-like activity was investigated in conditioned media of cell cultures derived from 4 human renal carcinomas. Transient production of PDGF-like factor was found only in the cell line derived from a subcutaneously growing metastasis. Further analysis of this cell line showed an increase of PDGF (A) gene activity in one cellular clone.
Sovová
V
V
Institute of Molecular Genetics, Czechoslovak Academy of Sciences, Praha.
Sloncová
E
E
Damková
M
M
Vydra
J
J
Jakoubková
J
J
D015152:Blotting, Northern; D002277:Carcinoma / Q000378:metabolism* / Q000556:secondary*; D003470:Culture Media; D015342:DNA Probes; D005786:Gene Expression Regulation; D006801:Humans; D007680:Kidney Neoplasms / Q000378:metabolism*; D010982:Platelet-Derived Growth Factor / Q000096:biosynthesis* / Q000235:genetics; D012878:Skin Neoplasms / Q000378:metabolism / Q000556:secondary; D014407:Tumor Cells, Cultured
D003470:Culture Media; D015342:DNA Probes; D010982:Platelet-Derived Growth Factor; C075278:platelet-derived growth factor A