title: Locating the central sulcus: comparison of MR anatomic and magnetoencephalographic functional methods.
abstract: OBJECTIVE
  To compare MR anatomic and magnetoencephalographic (MEG) functional methods in locating the central sulcus.
  
  
  METHODS
  Eleven healthy subjects and five patients with focal cerebral lesions were studied. The central sulcus was located anatomically with MR by two independent observers using axial vertex and sagittal (midline and lateral) images. Locations via the MEG functional method were based on detecting the somatosensory-evoked magnetic fields elicited by painless tactile stimuli.
  
  
  RESULTS
  The axial method yielded the most consistent interrater results, with complete agreement in 76% of sections in both control subjects and patients. The intermethod discordance of the sagittal midline and lateral methods was 32% in control subjects and 33% in patients. The concordance of MR and MEG methods ranged from 55% to 84% in control subjects and 65% to 67% in patients.
  
  
  CONCLUSIONS
  MR anatomic techniques can usually identify the central sulcus, but in the presence of anatomic distortion, the MEG functional method adds significant information.
authors.affiliation: Division of Neuroradiology, Scripps Clinic and Research Foundation, La Jolla, CA 92037.
authors.forename: D F
authors.initials: DF
authors.lastname: Sobel
authors.forename: C C
authors.initials: CC
authors.lastname: Gallen
authors.forename: B J
authors.initials: BJ
authors.lastname: Schwartz
authors.forename: T A
authors.initials: TA
authors.lastname: Waltz
authors.forename: B
authors.initials: B
authors.lastname: Copeland
authors.forename: S
authors.initials: S
authors.lastname: Yamada
authors.forename: E C
authors.initials: EC
authors.lastname: Hirschkoff
authors.forename: F E
authors.initials: FE
authors.lastname: Bloom
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged