Urea salvage in a neonate with cloacal exstrophy.
Urea kinetics were measured in a child with congenital absence of the colon on days 15, 19, and 23 of age. Urea salvage was 5% of urea production in the first study, increasing to 79% by the third. This provides evidence that the colonic microflora play a more active part in urea salvage than the mucosa and that the establishment of an active lower ileal microflora takes over some of the metabolic functions of the intact colon.
Wheeler
R A
RA
Wessex Regional Centre for Paediatric Surgery, London.
Griffiths
D M
DM
Jackson
A A
AA
D002988:Cloaca / Q000002:abnormalities*; D003106:Colon / Q000002:abnormalities*; D005260:Female; D006801:Humans; D007081:Ileostomy; D007082:Ileum / Q000378:metabolism / Q000382:microbiology; D007231:Infant, Newborn; D007234:Infant, Premature / Q000378:metabolism*; D009584:Nitrogen / Q000378:metabolism; D014508:Urea / Q000378:metabolism / Q000493:pharmacokinetics* / Q000652:urine; D014519:Ureterostomy
D014508:Urea; D009584:Nitrogen