Oesophageal cancer in gastric surgery patients.
Oesophageal adenocarcinoma (which has been steadily increasing in incidence during the last 20 years) is thought to be promoted by gastric reflux. In a cohort of 5018 gastric surgery patients, 19 of whom developed oesophageal cancer, there was no increased proportion of adenocarcinomas. We conclude that the hypothesized aetiology was not supported.
Caygill
C P
CP
PHLS Communicable Disease Surveillance Centre, London, UK.
Hill
M J
MJ
Kirkham
J S
JS
Northfield
T C
TC
D000230:Adenocarcinoma / Q000453:epidemiology* / Q000401:mortality; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000401:mortality; D002423:Cause of Death; D004938:Esophageal Neoplasms / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D005743:Gastrectomy / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D008131:London / Q000453:epidemiology; D008297:Male; D010437:Peptic Ulcer / Q000601:surgery; D012307:Risk Factors; D015167:Vagotomy, Truncal / Q000706:statistics & numerical data