Laminin and aminoterminal propeptide of type III procollagen in seminal plasma from fertile and vasectomized men.
The components of the extracellular matrix, laminin and aminoterminal propeptide of type III procollagen (PIIINP) were determined in seminal plasma of 50 patients with vasectomy and of 50 age-matched fertile patients. The concentration of laminin was highly significantly (P < 0.001) elevated in the fertile group as compared to the vasectomy group, whereas the concentrations of PIIINP were not significantly different between these two groups. Only weak correlations were observed between the concentrations of laminin and PIIINP. It is suggested that part of the laminin found in seminal plasma is derived from the ductus deferens, while the source of PIIINP is probably located at an upper part of the urogenital tract.
Geipel
U
U
Department of Clinical Chemistry, Philipps-University, Marburg, Germany.
Kropf
J
J
Bürgi
W
W
Gressner
A M
AM
D000328:Adult; D006801:Humans; D007797:Laminin / Q000032:analysis*; D008297:Male; D010446:Peptide Fragments / Q000032:analysis*; D011347:Procollagen / Q000032:analysis*; D012661:Semen / Q000737:chemistry*; D014659:Vasectomy
D007797:Laminin; D010446:Peptide Fragments; D011347:Procollagen; C041876:procollagen Type III-N-terminal peptide