Laboratory methods for diagnosing and monitoring HIV infection.
The authors provide a brief review of laboratory methods used to diagnose infection, monitor HIV disease progression, and monitor response to treatment in the HIV-infected person. Included are descriptions of the characteristics of the HIV virus, and the immune damage that results from HIV infection. The authors describe the antibody tests, tests of the virus, "surrogate markers" of disease progression, and immune parameters. Nurses' understanding of these tests will facilitate effective patient monitoring and education.
Grady
C
C
National Center for Nursing Research, National Institutes of Health, Bethesda, MD.
Vogel
S
S
D015492:AIDS Serodiagnosis / Q000295:instrumentation / Q000379:methods*; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D016655:HIV Core Protein p24 / Q000097:blood; D015658:HIV Infections / Q000097:blood* / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology / Q000451:nursing; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D001613:beta 2-Microglobulin / Q000032:analysis
D016655:HIV Core Protein p24; D001613:beta 2-Microglobulin