Transient aplasia preceding adult acute lymphoblastic leukemia.
A 62-year-old woman developed common acute lymphoblastic leukemia (ALL) after spontaneous recovery from transient marrow aplasia. Although the mechanisms underlying bone marrow suppression in acute leukemia are obscure, it is important to know that transient aplasia may be observed as a prodromal feature in ALL in adult patients as well as in children.
D'Alessio
A
A
Clinica Medica 2, Università, IRCCS Policlinico San Matteo, Pavia, Italy.
Invernizzi
R
R
Bernuzzi
S
S
Fiamenghi
C
C
Giusto
M
M
Iannone
A M
AM
D000741:Anemia, Aplastic / Q000097:blood / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000473:pathology; D011289:Preleukemia / Q000097:blood / Q000473:pathology