Occupational exposures and thyroid cancer: results of a case-control study.
A case-control study on thyroid cancer concerning 180 cases and 360 controls aged 20-70 years at diagnosis was performed. Both females and males were included. Of the cases, 63% had had papillary thyroid cancer. Work with diagnostic X-ray investigations constituted a risk factor for thyroid cancer of the papillary type yielding an odds ratio (OR) of 2.9 with 95% confidence interval (CI) = 1.1-8.3. For women only OR was 3.3 (CI = 1.2-9.8). The results also indicated that work as a lineman, which entails exposure to electromagnetic fields and chemicals, increased the risk. Exposure to impregnating agents gave an increased OR = 2.8 with CI = 1.0-8.6. For men only OR was 3.8 with CI = 1.1-16. Women who were previously smokers and female current smokers had significantly decreased risks with OR = 0.5 (CI = 0.2-0.96) and OR = 0.6 (CI = 0.3-0.96), respectively.
Hallquist
A
A
Department of Oncology, University Hospital, Umeå, Sweden.
Hardell
L
L
Degerman
A
A
Boquist
L
L
D000230:Adenocarcinoma / Q000453:epidemiology / Q000473:pathology; D000328:Adult; D000368:Aged; D002273:Carcinogens; D002277:Carcinoma / Q000453:epidemiology* / Q000473:pathology; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000473:pathology; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D009790:Occupations; D012111:Residence Characteristics; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D013548:Sweden / Q000453:epidemiology; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000473:pathology; D013997:Time Factors; D014881:Water Supply
D002273:Carcinogens