Studies on chemotherapy of parasitic helminths: efficacy of artemether on Japanese strain of Schistosoma japonicum in mice.
Effects of artemether were examined on Schistosoma japonicum in mice. When the drug was given at a daily dosage of 200 mg/kg for 4 successive days from 46 days post-infection, a significant reduction in worm recovery was observed. A significant reduction in size of worms from the medicated mice was also seen compared with that from non-medicated controls.
Sano
M
M
Department of Parasitology, Hamamatsu University School of Medicine, Japan.
Akyol
C V
CV
Tungtrongchitr
A
A
Ito
M
M
Ishih
A
A
D000818:Animals; D000077549:Artemether; D037621:Artemisinins; D005260:Female; D051379:Mice; D012549:Schistosoma japonicum / Q000187:drug effects; D012554:Schistosomiasis japonica / Q000188:drug therapy*; D012556:Schistosomicides / Q000627:therapeutic use*; D012717:Sesquiterpenes / Q000627:therapeutic use*; D013997:Time Factors
D037621:Artemisinins; D012556:Schistosomicides; D012717:Sesquiterpenes; D000077549:Artemether