title: Cytodiagnosis of breast disease using a liquid suspension medium.
abstract: Fine-needle aspiration cytology specimens from 187 breast lesions were processed using conventional slide cytology. Results were compared with those from 201 lesions prepared using a liquid suspension medium (Cytospin) for specimen collection, to assess the clinical utility of each technique. The frequency of diagnostic groups was similar for each method. No significant difference was found in sensitivity (conventional slide cytology 86 per cent versus Cytospin 82 per cent), specificity (72 versus 82 per cent) or diagnostic accuracy (88 versus 91 per cent). The Cytospin technique compares favourably with conventional slide cytology and can be recommended for ease of use in breast cytodiagnosis.
authors.affiliation: Department of Surgery, Royal Hampshire County Hospital, Winchester, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Ross
authors.forename: S C
authors.initials: SC
authors.lastname: Cunningham
authors.forename: A C
authors.initials: AC
authors.lastname: Vincenti
authors.forename: R M
authors.initials: RM
authors.lastname: Rainsbury
mesh_terms: D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology*; D003470:Culture Media; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods
chemical_list: D003470:Culture Media