title: Treatment of experimental canine carotid aneurysms with platinum coils.
abstract: OBJECTIVE
  To evaluate and compare the deliverability, positioning, stability, and effectiveness of aneurysm occlusion and the incidence of parent-artery thrombosis of two different types of platinum coils, using a canine carotid aneurysm model.
  
  
  METHODS
  29 experimental canine carotid aneurysms (19 lateral, 6 bifurcation, and 4 terminal) were constructed and treated with complex-shaped fibered platinum coils and simple curved nonfibered platinum Guglielmi detachable coils (GDCs).
  
  
  RESULTS
  Fibered complex coils were stable, producing 38% complete aneurysm occlusion and 61% average reduction in aneurysm lumen size but resulting in 19% parent artery occlusions. GDC coils were stable, producing 31% complete aneurysm occlusion and 95% average reduction in aneurysm lumen size with no parent-artery occlusions.
  
  
  CONCLUSIONS
  GDC coils produced an average reduction in aneurysm lumen size of 95% without any associated parent-artery occlusions. There were no delayed migrations of GDC coils. The ability to remove, reposition, and detach a coil was the most significant feature of the GDC coil.
authors.affiliation: Department of Radiology, University of Wisconsin Clinical Science Center, Madison 53792-0001.
authors.forename: V B
authors.initials: VB
authors.lastname: Graves
authors.forename: C M
authors.initials: CM
authors.lastname: Strother
authors.forename: A H
authors.initials: AH
authors.lastname: Rappe
mesh_terms: D000783:Aneurysm / Q000628:therapy*; D000818:Animals; D002340:Carotid Artery Diseases / Q000628:therapy*; D004285:Dogs; D004621:Embolization, Therapeutic / Q000379:methods*; D010984:Platinum
chemical_list: D010984:Platinum