RNA drug therapy acting via the 2-5A synthetase/RNase L pathway.
Suhadolnik
R J
RJ
Department of Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
Reichenbach
N L
NL
Hitzges
P M
PM
Ablashi
D V
DV
Strayer
D R
DR
Carter
W A
WA
D015088:2',5'-Oligoadenylate Synthetase / Q000378:metabolism*; D004311:Double-Blind Method; D004722:Endoribonucleases / Q000378:metabolism*; D015673:Fatigue Syndrome, Chronic / Q000188:drug therapy* / Q000201:enzymology; D006801:Humans; D011070:Poly I-C / Q000627:therapeutic use*; D011072:Poly U / Q000627:therapeutic use*; D012330:RNA, Double-Stranded / Q000627:therapeutic use*
D012330:RNA, Double-Stranded; D011072:Poly U; C047490:poly(I).poly(c12,U); D015088:2',5'-Oligoadenylate Synthetase; D004722:Endoribonucleases; C031956:2-5A-dependent ribonuclease; D011070:Poly I-C