title: Connective tissue diseases: advances in diagnosis and management.
abstract: Connective tissue diseases encompass a group of multisystem inflammatory syndromes whose pathogenesis is thought to be autoimmune. They are all associated with the production of autoantibodies that bind to predominantly intracellular antigens. We will describe recent advances that have led to improved classification and more accurate prognosis.
authors.affiliation: Rheumatology Unit, Hammersmith Hospital, London.
authors.forename: T J
authors.initials: TJ
authors.lastname: Vyse
authors.forename: M J
authors.initials: MJ
authors.lastname: Walport
mesh_terms: D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000628:therapy*; D003240:Connective Tissue Diseases / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology
chemical_list: D001323:Autoantibodies