title: Localized Wegener's granulomatosis relapsing as diffuse massive intra-alveolar hemorrhage.
abstract: In a 75-year-old patient presenting with a solitary pulmonary mass, a localized form of Wegener's granulomatosis was diagnosed after lobectomy. In the absence of extrapulmonary manifestations and after a benign postoperative course, the patients was discharged without medical treatment. Three months later, diffuse alveolar hemorrhage developed abruptly, necessitating mechanical ventilation, and was followed by cardiac complications and a fatal outcome. This case and another previously reported strongly suggest the need for medical treatment in patients with a localized form of pulmonary Wegener's granulomatosis, even when complete remission after surgical resection of the lung lesion seems to have been achieved.
authors.affiliation: Department of Internal Medicine B, B'nai Zion Medical Center, Haifa, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Odeh
authors.forename: L A
authors.initials: LA
authors.lastname: Best
authors.forename: H
authors.initials: H
authors.lastname: Kerner
authors.forename: H
authors.initials: H
authors.lastname: Bassan
authors.forename: A
authors.initials: A
authors.lastname: Oliven
mesh_terms: D000368:Aged; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000601:surgery; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000601:surgery; D011013:Pneumonectomy; D012008:Recurrence