Idiopathic peripheral gangrene in Nigeria.
A severe, acutely evolving peripheral gangrene of unknown etiology has been reported sporadically from different parts of Africa. This case report describes such a case of fulminant gangrene of the extremities following a febrile diarrheal illness associated with abdominal pain, polyarthropathy, and altered hemostatic function in a black adolescent male. A model of autoimmune causation for this uncommon clinical syndrome is proposed with guidelines for therapy.
Adogu
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AA
Department of Clinical Medicine, Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria.
Abengove
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CU
D000208:Acute Disease; D000293:Adolescent; D000671:Amputation, Surgical; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D003967:Diarrhea / Q000150:complications; D005334:Fever / Q000150:complications; D005734:Gangrene / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D006801:Humans; D007866:Leg; D008297:Male; D009549:Nigeria