title: Somatosensory evoked potentials after iohexol myelography.
abstract: Tibial nerve and S1 dermatome somatosensory evoked potentials (SSEPs) were recorded before and after iohexol lumbar myelography in order to evaluate possible neurotoxic effects of this contrast medium. No significant change in SSEP latencies nor amplitudes was noted after iohexol myelography, supporting the low neurotoxic profile of this contrast agent. Results were compared to those of a control group of patients before and after lumbar puncture (LP), without injection of contrast agent. In this group also no significant change in SSEP components was found, indicating that a preceding LP does not affect this electrophysiological examination.
authors.affiliation: Department of Clinical Neurophysiology, St. Lucas Hospital, Amsterdam, The Netherlands.
authors.forename: J G
authors.initials: JG
authors.lastname: Imanse
authors.forename: D M
authors.initials: DM
authors.lastname: Laman
authors.forename: H
authors.initials: H
authors.lastname: van Duijn
mesh_terms: D000328:Adult; D000368:Aged; D002490:Central Nervous System / Q000187:drug effects; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D007472:Iohexol / Q000633:toxicity*; D008297:Male; D008875:Middle Aged; D009192:Myelography; D009422:Nervous System Diseases / Q000000981:diagnostic imaging; D013129:Spinal Puncture; D013979:Tibial Nerve / Q000187:drug effects
chemical_list: D007472:Iohexol