title: [Cardiorespiratory and metabolic changes during prolonged exercise at 50% of the maximal load. Application to rehabilitation of severe cardiac insufficiencies].
abstract: The object of physical training in patients with chronic cardiac failure and severe left ventricular dysfunction is to improve skeletal muscle adaptation without impairing myocardial function. It is acknowledged that aerobic exercise limits increased ventricular strain. Therefore, the authors decided to determine whether exercise at 50% maximal power load constituted aerobic training. Eight patients with chronic cardiac failure (age 57 +/- 10 years; resting radionuclide ejection fraction: 25 +/- 5%) performed a rectangular submaximal exercise for 20 minutes at 50% of maximal aerobic load (MAL) as determined by a prior triangular exercise test at 10 W/mn (MAL = 92 +/- 26 Watts-Peak VO2 = 14.8 +/- 2.4 ml/Kg/mn). Gaseous exchanges (VO2, VCO2) minute volume (MV) and serum lactates were measured at rest and every 5 minutes during exercise. MV, VO2 and VCO2 increased significantly (p < 0.005) with a change of less than 5% between the 20th and 10th minute. Respiratory quotient was unchanged until the end of exercise and serum lactate levels stabilised between the 10th (3.4 +/- 0.66 mmol/l) and the 20th minute of exercise (3.5 +/- 0.47 mmol/l). No significant relationship was observed between ventilation and serum lactate or between respiratory quotient and serum lactate. These results confirm that exercise at 50% of maximal load is aerobic training even in patients with severe left ventricular dysfunction. This parameter would appear to be more useful than using the heart rate which is often abnormal in chronic cardiac failure (abnormal chronotropic response, atrial or ventricular arrhythmias).
authors.affiliation: Centre de réadaptation Rocheplane, Meylan.
authors.forename: E
authors.initials: E
authors.lastname: Page
authors.forename: P
authors.initials: P
authors.lastname: Flore
authors.forename: B
authors.initials: B
authors.lastname: Aguilaniu
authors.forename: C
authors.initials: C
authors.lastname: Hebert
authors.forename: R
authors.initials: R
authors.lastname: Brazier
authors.forename: J J
authors.initials: JJ
authors.lastname: Papassin
mesh_terms: D000332:Aerobiosis; D000368:Aged; D017079:Exercise Tolerance; D005260:Female; D006333:Heart Failure / Q000503:physiopathology* / Q000534:rehabilitation; D006801:Humans; D007773:Lactates / Q000097:blood; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism; D012119:Respiration
chemical_list: D007773:Lactates; D010100:Oxygen
vernacular_title: Modifications cardiorespiratoires et métaboliques au cours d'un effort prolongé à 50% de la charge maximale. Application à la rééducation des insuffisants cardiaques sévères.