Rhabdomyolysis syndrome in children: report of three cases.
Three cases with distinct clinical manifestations associated with rhabdomyolysis syndrome were encountered in this hospital's pediatric intensive care unit. Elevation of serum creatine phosphokinase, uric acid, potassium, inorganic phosphate and hypocalcemia with seizure were noted. The three patients all had signs of acute renal failure. One died of respiratory failure, and autopsy revealed multiple intrathoracic anomalies. The remaining two recovered completely from rhabdomyolysis. It is of importance to early recognize any acutely ill patient as having rhabdomyolysis syndrome when there is elevation of muscle enzymes, hypocalcemic seizure, positive orthotolidine reaction of urine strip while negative finding of red blood cell. The syndrome may damage the kidneys. Appropriate management to induce diuresis usually can salvage this potentially life-threatening condition.
Huang
S J
SJ
Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.
Yen
D C
DC
Tsau
Y K
YK
Tsai
W S
WS
Chen
C H
CH
D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012206:Rhabdomyolysis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D013577:Syndrome