title: Laryngeal chondrosarcomas.
abstract: Four cases of laryngeal chondrosarcoma are presented. The patients' ages ranged from 60 to 75 years; one was a man and three were women. Two of the tumors arose in the thyroid cartilage, one in the cricoid cartilage, and one in the left arytenoid cartilage. A rapid fatal course with pulmonary and cerebral metastases was observed for the tumor arising in the arytenoid cartilage that histologically corresponded to a myxoid chondrosarcoma. The other three cases corresponded to low-grade, well-differentiated chondrosarcomas of the hyaline type, and the patients were alive and free of recurrence or metastases 3 to 6 years following total and partial laryngectomy. A review of the literature on the topic and the importance of assessing histologic grade, size, and location in the evaluation of these neoplasms is discussed.
authors.affiliation: Department of Surgical Pathology, Yale-New Haven, Conn.
authors.forename: C A
authors.initials: CA
authors.lastname: Moran
authors.forename: S
authors.initials: S
authors.lastname: Suster
authors.forename: D
authors.initials: D
authors.lastname: Carter
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000556:secondary*; D002813:Chondrosarcoma / Q000556:secondary*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged