title: Application of a conformationally restricted Phe-Leu dipeptide mimetic to the design of a combined inhibitor of angiotensin I-converting enzyme and neutral endopeptidase 24.11.
authors.affiliation: Marion Merrell Dow Research Institute, Cincinnati, Ohio 45215.
authors.forename: G A
authors.initials: GA
authors.lastname: Flynn
authors.forename: D W
authors.initials: DW
authors.lastname: Beight
authors.forename: S
authors.initials: S
authors.lastname: Mehdi
authors.forename: J R
authors.initials: JR
authors.lastname: Koehl
authors.forename: E L
authors.initials: EL
authors.lastname: Giroux
authors.forename: J F
authors.initials: JF
authors.lastname: French
authors.forename: P W
authors.initials: PW
authors.lastname: Hake
authors.forename: R C
authors.initials: RC
authors.lastname: Dage
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000737:chemistry*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D015260:Neprilysin / Q000037:antagonists & inhibitors / Q000737:chemistry*; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000494:pharmacology; D011487:Protein Conformation; D051381:Rats; D011918:Rats, Inbred SHR; D013329:Structure-Activity Relationship; D013566:Sympathomimetics / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D009842:Oligopeptides; D013566:Sympathomimetics; D015260:Neprilysin