title: Asymmetrical hypersensitivity to bovine collagen.
abstract: We report a unique patient with true asymmetrical hypersensitivity to bovine collagen. Hypersensitivity is the development of an inflammatory response at a treatment site after a negative skin test. She developed an inflammatory response in only one of two simultaneously injected sites. About 1.5% of patients with a negative skin test have a hypersensitivity reaction consisting of firmness, erythema, and swelling. The signs and symptoms generally resolve spontaneously in a few months.
authors.affiliation: University of Rochester, Division of Plastic Surgery, NY 14642.
authors.forename: P
authors.initials: P
authors.lastname: Somerville
authors.forename: R C
authors.initials: RC
authors.lastname: Wray
mesh_terms: D000328:Adult; D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D002417:Cattle; D003094:Collagen / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology*; D005260:Female; D005546:Forehead; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D019736:Prostheses and Implants / Q000009:adverse effects*; D015595:Skin Aging; D012882:Skin Tests
chemical_list: D001672:Biocompatible Materials; C048470:glutaraldehyde-cross-linked collagen; D003094:Collagen