Synthesis of (3'-5'),(2'-5')-linked di- and tri-adenylyl methylphosphonate analogs.
Stereoselectivity was found during the coupling reaction, to form 2',5'- and 3',5'-linked di- and triadenylyl methylphosphonate. The configuration of phosphorus was determined by 1HNMR NOE.
Wang
C G
CG
School of Pharmaceutical Sciences, Beijing Medical University, China.
Wang
L X
LX
Yang
X B
XB
Jiang
T Y
TY
Zhang
L H
LH
D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D009943:Organophosphorus Compounds; C032627:methylphosphonic acid