A rapid test for the detection of human immunodeficiency virus antibodies in cord blood.
A commercially available rapid test (HIVCHEK) was compared with an enzyme-linked immunosorbent assay (ELISA) for identifying human immunodeficiency virus type 1 in the serum of newborn infants. Of 1309 cord blood samples tested, the HIVCHEK test detected all the true-positive samples detected by ELISA. Of the 35 samples with positive ELISA results, six had negative results on Western blot; only 1 of the 30 samples with positive HIVCHEK results had negative results on Western blot. Thus the HIVCHEK test can be used to facilitate the rapid identification of HIV-1 in the serum of newborn infants.
Suarez
M A
MA
Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY 10461.
Blanco
B
B
Brion
L P
LP
Schulman
M
M
Calvelli
T A
TA
Youchah
J
J
Devash
Y
Y
Rubinstein
A
A
Goldstein
H
H
D003124:Colorimetry; D004797:Enzyme-Linked Immunosorbent Assay; D005188:False Negative Reactions; D005189:False Positive Reactions; D005312:Fetal Blood / Q000276:immunology* / Q000382:microbiology; D015483:HIV Antibodies / Q000097:blood*; D015488:HIV Antigens / Q000097:blood*; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D013997:Time Factors
D015483:HIV Antibodies; D015488:HIV Antigens