Fasting hyperglycemia in type I diabetes mellitus.
The differential diagnosis of fasting hyperglycemia in type I diabetes includes the Somogyi effect, the dawn phenomenon, and insufficient insulin administration. To determine the causes of fasting hyperglycemia and their effect on subsequent daytime blood glucose control, the authors retrospectively reviewed blood glucose profiles of 126 patients with type I diabetes. The Somogyi effect accounted for 12.6% of all instances of fasting hyperglycemia, the dawn phenomenon, 24.1%, and poor control, 63.3%. Measurement of 3 AM and 5 AM blood glucose values is the key to making a correct diagnosis. Once a patient's fasting hyperglycemia is placed in one of these groups, appropriate treatment can be started.
Mozersky
R P
RP
Division of Endocrinology, Shadyside Hospital, Pittsburgh, PA 15232.
Bahl
V K
VK
Patel
H
H
Patel
N
N
Palushock
S
S
Yamakawa
H
H
Mook
W
W
Basuray
R
R
Velez-Giraldo
J R
JR
D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D002940:Circadian Rhythm; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000150:complications / Q000188:drug therapy; D005215:Fasting; D005260:Female; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D006943:Hyperglycemia / Q000097:blood* / Q000209:etiology / Q000503:physiopathology; D007328:Insulin / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D001786:Blood Glucose; D007328:Insulin; D013006:Growth Hormone; D006854:Hydrocortisone