Presence of serum antibodies to coagulation protein C in patients with systemic lupus erythematosus is not associated with antigenic or functional protein C deficiencies.
Antibodies directed to immunopurified coagulation protein C (PC) were investigated in serum samples from 108 patients with systemic lupus erythematosus (SLE) and found in 12 of them. However, their presence was not associated with antigenic or functional deficiencies of PC, which were documented in 6 and 17 patients, respectively.
Ruiz-Arguelles
A
A
Laboratorios Clinicos de Puebla, Instituto Nacional de la Nutricion Salvador Zubiran, Mexico City, Mexico.
Vazquez-Prado
J
J
Deleze
M
M
Perez-Romano
B
B
Drenkard
C
C
Alarcon-Segovia
D
D
Ruiz-Arguelles
G J
GJ
D000906:Antibodies / Q000032:analysis* / Q000276:immunology; D001777:Blood Coagulation / Q000502:physiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology*; D011486:Protein C / Q000276:immunology* / Q000502:physiology; D020151:Protein C Deficiency
D000906:Antibodies; D011486:Protein C