title: Comparison of the in vitro effects of several cephalosporins on the oxidative burst of human phagocytes.
abstract: The metabolic activity (oxygen radical formation) of human phagocytes was not substantially affected by the tested cephalosporins. Therapeutic concentrations caused only a mild suppression or immunopotentiation in some cases or there were no effects altogether.
authors.affiliation: Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno.
authors.forename: D
authors.initials: D
authors.lastname: Kubícková
authors.forename: L
authors.initials: L
authors.lastname: Benes
authors.forename: A
authors.initials: A
authors.lastname: Lojek
authors.forename: M
authors.initials: M
authors.lastname: Cíz
authors.forename: J
authors.initials: J
authors.lastname: Pillich
mesh_terms: D002439:Cefotaxime / Q000494:pharmacology; D002441:Cefsulodin / Q000494:pharmacology; D002442:Ceftazidime / Q000494:pharmacology; D002443:Ceftriaxone / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D009504:Neutrophils / Q000187:drug effects / Q000378:metabolism; D010084:Oxidation-Reduction; D010586:Phagocytes / Q000187:drug effects* / Q000378:metabolism; D016897:Respiratory Burst / Q000187:drug effects*
chemical_list: D002511:Cephalosporins; D002443:Ceftriaxone; D002442:Ceftazidime; D002439:Cefotaxime; D002441:Cefsulodin