title: p53 protein expression in Reed-Sternberg cells of Hodgkin's disease.
abstract: Hodgkin's disease (HD) is perceived to be a malignant disease of the lymphoid system. One of the main obstacles into the investigation of the cell biology of Hodgkin's disease is the relative paucity of Reed-Sternberg cells (or variants), the presumed neoplastic component of this condition, which often make up less than 1% of the total cell number.
authors.affiliation: ICRF Department of Medical Oncology, St. Bartholomew's Hospital, London, England, UK.
authors.forename: R K
authors.initials: RK
authors.lastname: Gupta
authors.forename: A J
authors.initials: AJ
authors.lastname: Norton
authors.forename: T A
authors.initials: TA
authors.lastname: Lister
authors.forename: J G
authors.initials: JG
authors.lastname: Bodmer
mesh_terms: D002467:Cell Nucleus / Q000737:chemistry; D016158:Genes, p53 / Q000235:genetics; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D016539:Reed-Sternberg Cells / Q000737:chemistry*; D016159:Tumor Suppressor Protein p53 / Q000032:analysis*
chemical_list: D016159:Tumor Suppressor Protein p53