Recurrent apparent life-threatening events during infancy: a manifestation of inborn errors of metabolism.
To determine how often inborn errors of metabolism may cause unexplained apnea or recurrent apparent life-threatening events in infants, we retrospectively reviewed the records of 166 infants who were referred for apnea evaluation. A metabolic disorder was identified in 7 infants (4.2%), all of whom had recurrent apparent life-threatening events.
Arens
R
R
Division of Neonatology and Pediatric Pulmonology, Childrens Hospital Los Angeles, CA 90027.
Gozal
D
D
Williams
J C
JC
Ward
S L
SL
Keens
T G
TG
D001049:Apnea / Q000209:etiology* / Q000401:mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008661:Metabolism, Inborn Errors / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology*; D012008:Recurrence; D012189:Retrospective Studies