Synthesis and antimycobacterial activity of some 4-pyridinecarboxyamidrazone derivatives.
A series of N1-aryliden-4-pyridinecarboxyamidrazone derivatives was prepared. Some of the synthesized compounds showed interesting in vitro antimycobacterial activity against some strains of Mycobacterium and clinical isolates of Mycobacterium tuberculosis.
Mamolo
M G
MG
Dipartimento di Scienze Farmaceutiche, Facoltà di Farmacia, Università Degli Studi, Trieste, Italia.
Vio
L
L
Banfi
E
E
Predominato
M
M
Fabris
C
C
Asaro
F
F
D000995:Antitubercular Agents / Q000138:chemical synthesis / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects*; D009162:Mycobacterium avium / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology
D000995:Antitubercular Agents; D011725:Pyridines