title: Long-term results of treatment for axillary subclavian vein thrombosis.
abstract: Thrombolytic therapy is an effective method for reopening an occluded venous segment, but little is known about the long-term results of thrombolysis via direct intravenous route for axillary subclavian vein thrombosis (ASVT). Our experience with 13 cases of primary ASVT illustrates the possible advantages of a protocol consisting of lytic therapy, surgical decompression and percutaneous balloon angioplasty if a high-grade stenosis persists. If accompanied by adjunctive therapy to correct the underlying cause, thrombolytic therapy for ASVT results in acceptable long-term symptom relief and vein patency.
authors.affiliation: Department of Surgery, New England Medical Center, Boston, Mass 02111.
authors.forename: J
authors.initials: J
authors.lastname: Malcynski
authors.forename: T F
authors.initials: TF
authors.lastname: O'Donnell
authors.forename: W C
authors.initials: WC
authors.lastname: Mackey
authors.forename: V A
authors.initials: VA
authors.lastname: Millan
mesh_terms: D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon / Q000379:methods*; D000925:Anticoagulants / Q000627:therapeutic use; D001365:Axilla / Q000098:blood supply*; D015984:Causality; D002985:Clinical Protocols; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006358:Hot Temperature / Q000627:therapeutic use; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D013300:Streptokinase / Q000627:therapeutic use*; D013350:Subclavian Vein; D017131:Thrombectomy / Q000379:methods*; D015912:Thrombolytic Therapy / Q000379:methods*; D013927:Thrombosis / Q000145:classification / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*; D016896:Treatment Outcome; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*; D014654:Vascular Patency; D014680:Veins / Q000637:transplantation
chemical_list: D000925:Anticoagulants; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator