[Genetic effects of tritium-labeled amino acids in mice].
The frequency of dominant lethal mutations (DLM) in germ cells and the frequency of reciprocal translocations (RT) in spermatogonia of male mice exposed to H-labeled amino acids at the dose of 1.45-2.30 Gy was studied. The effect from H-glycine was equal to that from tritium oxide (THO). When D,L-lysine-3H and L-lysine-3H were injected into the body of mice the frequency of DLM exceeded that from the equal dose of THO by 2.5 and 7 times, respectively. As to RT, these indexes for H-amino acids have no statistically significant differences from the similar index for THO.
Zhesko
T V
TV
Balanov
M I
MI
Pomerantseva
M D
MD
Ramaĭia
L K
LK
D000596:Amino Acids / Q000008:administration & dosage*; D000818:Animals; D005260:Female; D005799:Genes, Dominant; D005804:Genes, Lethal; D008297:Male; D051379:Mice; D009154:Mutation; D013093:Spermatogonia / Q000528:radiation effects; D014178:Translocation, Genetic; D014316:Tritium / Q000009:adverse effects*
D000596:Amino Acids; D014316:Tritium
Geneticheskie éffekty mechennykh tritiem aminokislot u myshi.