title: Pneumothorax as a complication of tumour response to chemotherapy.
abstract: A patient with extensive pulmonary involvement by disseminated adenocarcinoma is presented. Response to chemotherapy resulted in the direct rupture of necrotic tumour tissue into the pleural cavity leading to a pneumothorax. The condition failed to improve with chest drainage and suction, necessitating surgical intervention. The development of the pneumothorax proved to be a fatal complication of treatment.
authors.affiliation: Department of Radiotherapy and Oncology, Charing Cross Hospital, London, UK.
authors.forename: M D
authors.initials: MD
authors.lastname: Leslie
authors.forename: M
authors.initials: M
authors.lastname: Napier
authors.forename: M G
authors.initials: MG
authors.lastname: Glaser
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D008875:Middle Aged; D011030:Pneumothorax / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D012422:Rupture, Spontaneous