title: Comparative bioavailability study of acetaminophen solutions used in hospital formulary.
abstract: To learn the influence of polyethylene glycol (PEG) on bioavailability, this study compared the bioavailability of acetaminophen in the presence of 10% ethanol (acetaminophen-ethanol liquid) to that in the presence of 10% PEG (acetaminophen-PEG liquid) since these two preparations are commonly used in hospital formulary. The results in Thai male volunteers showed there was not significantly different.
authors.affiliation: Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Prakongpan
authors.forename: R
authors.initials: R
authors.lastname: Puncoke
authors.forename: T
authors.initials: T
authors.lastname: Nagai
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage / Q000493:pharmacokinetics*; D000293:Adolescent; D000328:Adult; D001682:Biological Availability; D002851:Chromatography, High Pressure Liquid; D000431:Ethanol; D005572:Formularies, Hospital as Topic; D006801:Humans; D008297:Male; D011092:Polyethylene Glycols; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet
chemical_list: D012996:Solutions; D000082:Acetaminophen; D000431:Ethanol; D011092:Polyethylene Glycols