title: Risk factors involved in stomal recurrence following laryngectomy.
abstract: Stomal recurrence after surgery for laryngeal tumours is an extremely serious complication, with a dismal prognosis despite aggressive surgical therapy or high-dose irradiation. Data from 209 patients who underwent total laryngectomy for cancers of the larynx and hypopharynx were retrieved from the registry of the Department of Otorhinolaryngology at the Hospital 'Virgen de las Nieves' of Granada. Stomal recurrence developed in 8.1 per cent of them (17 cases). We analysed several parameters from each case: first, those parameters significantly associated with stomal recurrence were detected, and secondly, a logistic regression analysis was done. Three factors were found independently related to stomal recurrence: T-staging, site of the primary tumour and prior tracheostomy. Together with a review of the literature, we discuss our findings and a proposal for management of the high risk patient.
authors.affiliation: Department of Otorhinolaryngology, Virgen de las Nieves Hospital, Granada, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Esteban
authors.forename: J A
authors.initials: JA
authors.lastname: Moreno
authors.forename: M
authors.initials: M
authors.lastname: Delgado-Rodriguez
authors.forename: A
authors.initials: A
authors.lastname: Mochon
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000209:etiology*; D011184:Postoperative Period; D012189:Retrospective Studies; D012307:Risk Factors; D014134:Tracheal Neoplasms / Q000209:etiology*; D014139:Tracheostomy