[Mutations in mouse minisatellite DNA, induced by radiation].
Male (101/HY x C3H/SnY) F1-hybrid mice were given an acute exposure to 0.5 or 1 Gy gamma-irradiation using 60Co, and DNA fingerprints were produced from parents and progeny using probes 33.6 and 33.15. The frequency of mutations in the offspring of irradiated males was 1.72 times higher than in offspring of nonirradiated males. Possible implications of the DNA fingerprint technique in monitoring of mutations in human populations are discussed.
Dubrova
Iu E
IuE
Dzheffreĭz ADzh
Malashenko
A M
AM
D000818:Animals; D016172:DNA Fingerprinting; D004276:DNA, Satellite / Q000528:radiation effects*; D005720:Gamma Rays; D008297:Male; D051379:Mice; D009154:Mutation
D004276:DNA, Satellite
Mutatsii v minisatellitnoĭ DNK mysheĭ industirovannye radiatsieĭ.