title: Regional cerebral blood flow in Angelman syndrome.
abstract: A patient with typical features of Angelman syndrome--a genetically inherited disorder involving developmental delay, ataxia, episodes of paroxysmal laughter and brachiocephaly--was studied with single-photon emission tomography. Hypoperfusion found in the left frontal and left temporoparietal regions can provide insights into the functional cerebral pathology, which may be due to a disturbance of the developmental process related to a chromosomal abnormality.
authors.affiliation: Department of Pediatric Neurology, Faculty of Medicine, Gazi University, Besevler, Ankara, Turkey.
authors.forename: K
authors.initials: K
authors.lastname: Gücüyener
authors.forename: N
authors.initials: N
authors.lastname: Gökçora
authors.forename: N
authors.initials: N
authors.lastname: Ilgin
authors.forename: N
authors.initials: N
authors.lastname: Buyan
authors.forename: A
authors.initials: A
authors.lastname: Sayli
mesh_terms: D017204:Angelman Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002648:Child; D005260:Female; D006801:Humans; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime