title: [Clinical and microbiological study concerning effects of scaling and root planing. 2. The effects of mechanical debridement until one year and of minocycline application topically].
abstract: This study was performed to assess the effect of scaling and root planing clinically and microbiologically during one year. Nine patients with moderate to severe periodontitis were studied. After the process of plaque control, the selected single rooted teeth with 5mm probing depth were debrided mechanically under non-local anesthesia four times biweekly. Observing the results of the treated teeth until three months, the experimental teeth were divided into two groups. The standard of division was whether they showed good response to the mechanical debridement or not. Observation was continued until one year after the debridement according to the following criteria: 1. The sites which showed good responses at three months were continued to be observed biweekly. 2. The sites which showed no improvement at three months were applied the gel of minocycline (Periocline) four times biweekly. 3. The untreated sites used as control until three months received mechanical debridement four times biweekly. The following results were obtained: The sites that showed good responses to the mechanical debridement at three months were maintained in good condition continuously during one year. The topical application of Periocline was effective in reducing the inflammation and probing depth clinically and microbiologically until three months.
authors.affiliation: Department of Periodontology, Faculty of Dentistry, Tokyo Medical and Dental University.
authors.forename: S
authors.initials: S
authors.lastname: Hagiwara
authors.forename: M
authors.initials: M
authors.lastname: Iida
authors.forename: I
authors.initials: I
authors.lastname: Ishikawa
mesh_terms: D000287:Administration, Topical; D000328:Adult; D003646:Debridement; D012534:Dental Scaling; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage* / Q000627:therapeutic use; D010518:Periodontitis / Q000382:microbiology / Q000628:therapy*; D016745:Root Planing
chemical_list: D008911:Minocycline