Effect of streptozotocin-induced diabetes on electrically evoked erection in the rat.
This study was designed to investigate whether experimental diabetes in rats could functionally affect reflexogenic erection. Erection was elicited by means of electrical stimulation of the dorsal nerves of the penis and recorded as intracorporeal pressure. Rats were examined 1, 3 and 6 months after diabetes induction by streptozotocin. Three and 6 month diabetes caused a significant decrease of latency for erection and a slower phase of detumescence when compared to age-matched controls. In addition, a trend for a lower developed intracorporeal pressure was present in the 6 month diabetes group. Our results indicate that experimental diabetes is associated with alterations of reflexogenic erection.
Italiano
G
G
Fidia Research Laboratories, Abano Terme, Padua, Italy.
Marin
A
A
Pescatori
E S
ES
Calabrò
A
A
Artibani
W
W
Pagano
F
F
Triban
C
C
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000150:complications / Q000503:physiopathology*; D004558:Electric Stimulation; D008297:Male; D010410:Penile Erection / Q000502:physiology*; D010413:Penis / Q000294:innervation; D051381:Rats; D017207:Rats, Sprague-Dawley