[Survival, complications and quality of life in patients with breast cancer after ovariectomy and hormonal therapy].
Seventy one women with breast cancer in clinical stage IIIa were treated by chemotherapy and radical operation on the basis five features, namely: survivals, relapses, metastases, quality of life, and post-therapy complications. The two treatment methods were compared. The dependence between survivals and time elapsed between breast surgery and ovariectomy was evaluated. Women treated by ovariectomy suffer from; menopause symptoms, osteoporosis, blood coagulation distortions more after than women treated by hormonotherapy. Tamoxifen therapy increases the rate of breast cancer relapses and probably it is the cause of breast cancer metastases into liver. Women who underwent hormonal castration are professionally active more after them women treated by ovariectomy. Time elapsed between breast surgery and ovariectomy does not affect survivals in stage IIIa. In stage IIIb however, performing later ovariectomy prolongs survivals.
Czub
M
M
Katedry Onkologii AM, Poznaniu.
Markowska
J
J
Tomczak
P
P
Wiese
E
E
Markowski
M
M
D000328:Adult; D001943:Breast Neoplasms / Q000401:mortality / Q000628:therapy*; D003131:Combined Modality Therapy / Q000009:adverse effects; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000009:adverse effects; D008875:Middle Aged; D010052:Ovariectomy; D011788:Quality of Life; D012307:Risk Factors; D016019:Survival Analysis; D013629:Tamoxifen / Q000009:adverse effects
D013629:Tamoxifen
Przezycia, powikłania i jakość zycia u chorych na raka sutka po kastracji chirurgicznej i terapii hormonalnej.