Rapamycin inhibits lymphocyte proliferation in a popliteal lymph node model via an IL-2-independent mechanism.
Warner
L M
LM
Wyeth-Ayerst Research, Princeton, New Jersey 08543.
Lewis
G M
GM
Weichman
B M
BM
Sehgal
S N
SN
D000818:Animals; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007376:Interleukin-2 / Q000502:physiology*; D008198:Lymph Nodes / Q000187:drug effects / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects*; D051379:Mice; D008809:Mice, Inbred C3H; D011090:Polyenes / Q000494:pharmacology*; D020123:Sirolimus
D007166:Immunosuppressive Agents; D007376:Interleukin-2; D011090:Polyenes; D020123:Sirolimus