title: General distribution of the nitrogen control gene ntcA in cyanobacteria.
abstract: The ntcA gene from Synechococcus sp. strain PCC 7942 encodes a regulatory protein which is required for the expression of all of the genes known to be subject to repression by ammonium in that cyanobacterium. Homologs to ntcA have now been cloned by hybridization from the cyanobacteria Synechocystis sp. strain PCC 6803 and Anabaena sp. strain PCC 7120. Sequence analysis has shown that these ntcA genes would encode polypeptides strongly similar (77 to 79% identity) to the Synechococcus NtcA protein. Sequences hybridizing to ntcA have been detected in the genomes of nine other cyanobacteria that were tested, including strains of the genera Anabaena, Calothrix, Fischerella, Nostoc, Pseudoanabaena, Synechococcus, and Synechocystis.
authors.affiliation: Instituto de Bioquímica Vegetal y Fotosíntesis, Facultad de Biología, Universidad de Sevilla-Consejo Superior de Investigaciones Científicas, Spain.
authors.forename: J E
authors.initials: JE
authors.lastname: Frías
authors.forename: A
authors.initials: A
authors.lastname: Mérida
authors.forename: A
authors.initials: A
authors.lastname: Herrero
authors.forename: J
authors.initials: J
authors.lastname: Martín-Nieto
authors.forename: E
authors.initials: E
authors.lastname: Flores
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins; D001483:Base Sequence; D003001:Cloning, Molecular; D000458:Cyanobacteria / Q000235:genetics*; D004247:DNA / Q000302:isolation & purification; D004268:DNA-Binding Proteins; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D009584:Nitrogen / Q000378:metabolism; D015183:Restriction Mapping; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D014157:Transcription Factors; C075617:ntcA protein, Synechococcus; D004247:DNA; D009584:Nitrogen