title: [99mTc-HMPAO SPECT in the brain death--a case report].
abstract: Brain single photon emission computed tomography (SPECT) with 99mTc-d,l-hexamethyl-propyleneamine oxime (HMPAO) was performed twice in a 78-year-old man clinically diagnosed as brain death according to the standard criteria of the Japanese Ministry of Welfare. The first brain SPECT demonstrated the tracer accumulation in the brain, indicating preserved cerebral blood flow. The second brain SPECT performed 3 days later revealed cessation of the blood flow. In patients with preserved cerebral blood flow, the diagnosis of brain death cannot be made, even if they meet the existing criteria, because previous report noted the recovery in some of those patients. Brain perfusion SPECT plays an important role as a confirmatory test for the diagnosis of the brain death.
authors.affiliation: Department of Radiology and Nuclear Medicine, Kyoto University Faculty of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Tsuchida
authors.forename: N
authors.initials: N
authors.lastname: Sadato
authors.forename: S
authors.initials: S
authors.lastname: Nishizawa
authors.forename: N
authors.initials: N
authors.lastname: Matoba
authors.forename: T
authors.initials: T
authors.lastname: Fujita
authors.forename: N
authors.initials: N
authors.lastname: Tamaki
authors.forename: J
authors.initials: J
authors.lastname: Konishi
authors.forename: S
authors.initials: S
authors.lastname: Tamai
authors.forename: K
authors.initials: K
authors.lastname: Shingu
authors.forename: Y
authors.initials: Y
authors.lastname: Yonekura
mesh_terms: D000368:Aged; D001926:Brain Death / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime