Adhesion proteins on airway eosinophils in allergy and asthma.
Adhesion to, and interaction with, airway endothelium, interstitial matrix and epithelium during migration to the allergen-challenged airways of allergic rhinitis and asthma patients may account for the observed functional upregulation (priming) of airway eosinophils compared with corresponding blood eosinophils.
Sedgwick
J B
JB
Department of Medicine, University of Wisconsin, Madison 53792.
Busse
W W
WW
D000485:Allergens / Q000276:immunology; D000595:Amino Acid Sequence; D001249:Asthma / Q000276:immunology*; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D002448:Cell Adhesion / Q000502:physiology; D015815:Cell Adhesion Molecules / Q000097:blood*; D002470:Cell Survival / Q000502:physiology; D004804:Eosinophils / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D008969:Molecular Sequence Data; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology
D000485:Allergens; D015815:Cell Adhesion Molecules