Drug-induced pemphigus.
Drug-induced pemphigus is a heterogenous group of disorders in which a drug induces acantholysis. The majority of patients have immune features of pemphigus and have a course similar to idiopathic pemphigus. Few patients do not have a detectable autoimmune process, and their eruption usually resolves with discontinuation of the associated drug. The mechanism of induction of the autoimmune process and acantholysis is not clear.
Mutasim
D F
DF
Department of Dermatology, University of Cincinnati Medical Center, Ohio.
Pelc
N J
NJ
Anhalt
G J
GJ
D005455:Fluorescent Antibody Technique; D006801:Humans; D010392:Pemphigus / Q000139:chemically induced* / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000276:immunology / Q000473:pathology