title: Prevention of apical periodontal ligament pain: a preliminary report of 100 vital pulp cases.
abstract: A preliminary study was conducted in a private practice office to determine the incidence of postoperative pain in 100 vital pulp cases. An ophthalmic dexamethasone-neomycin solution was introduced within the root canal during the complete cleaning and shaping procedure with the purpose of premedicating and preventing apical periodontal ligament inflammation and pain. The postoperative pain outcome was compared between cases premedicated with intracanal dexamethasone-neomycin solution alone and in combination with an oral administration of Mesulide. Moderate pain was reported in 10 cases and tooth sensitivity in 13. The clinical results indicated no report of severe pain.
authors.affiliation: Postgraduate School of Endodontics of San Luis Potosi, Mexico.
authors.forename: A
authors.initials: A
authors.lastname: Calderon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002648:Child; D003907:Dexamethasone / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009355:Neomycin / Q000627:therapeutic use; D010149:Postoperative Pain / Q000517:prevention & control*; D010513:Periodontal Ligament / Q000503:physiopathology*; D010865:Pilot Projects; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D012390:Root Canal Therapy / Q000379:methods*; D013449:Sulfonamides / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004338:Drug Combinations; D012388:Root Canal Irrigants; D013449:Sulfonamides; D003907:Dexamethasone; D009355:Neomycin; C012655:nimesulide