title: Evaluation of computed tomography in patients with peritoneal carcinomatosis.
abstract: BACKGROUND
  Radiologic tests to determine the size and location of cancer on peritoneal surfaces are needed for patient management and for clinical research activity.
  
  
  METHODS
  Computed tomography (CT) of the abdomen and pelvis were obtained on 45 patients with a diagnosis of peritoneal carcinomatosis before implementation of a complete exploratory laparotomy with biopsy or resection of all tissues suspicious of malignancy. CT findings and surgical findings were recorded and the data analyzed by dividing the abdomen into 9 regions or into 15 anatomic sites.
  
  
  RESULTS
  In an overall patient analysis, the sensitivity was 79%. In the nine different abdominal regions, sensitivity was greater than 80% in the right flank, left flank, and right lower and left lower abdominal regions. Sensitivity was lowest in the pelvis (60%). Negative predictive value in the pelvis was 20%. The volume of tumor present within an abdominal region or anatomic site greatly influenced the sensitivity. A sensitivity of only 28% was recorded when tumor nodules were less than 0.5 cm in thickness. This increased to 90% when nodule thickness was greater than 5 cm.
  
  
  CONCLUSIONS
  CT is not a reliable diagnostic test for low volume tumor on peritoneal surfaces, and the greatest inaccuracies were recorded in the pelvis. Its diagnostic value increased as tumor volume increased.
authors.affiliation: Chirurgie Abdominole et generale, Centre Hospital University Liege, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Jacquet
authors.forename: J S
authors.initials: JS
authors.lastname: Jelinek
authors.forename: M A
authors.initials: MA
authors.lastname: Steves
authors.forename: P H
authors.initials: PH
authors.lastname: Sugarbaker
mesh_terms: D000005:Abdomen / Q000473:pathology; D000328:Adult; D000368:Aged; D001063:Appendiceal Neoplasms / Q000473:pathology; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary; D003110:Colonic Neoplasms / Q000473:pathology; D003536:Cystadenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D010388:Pelvis / Q000000981:diagnostic imaging / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary; D011446:Prospective Studies; D011860:Radiography, Abdominal; D012004:Rectal Neoplasms / Q000473:pathology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed