Histopathology of the vessels of the femoral heads in specimens of osteonecrosis, osteoarthritis and algodystrophy.
The authors studied by light microscopy the vessels of the femoral head and neck in 38 well preserved specimens from core biopsy. There were 17 cases of osteonecrosis (ON), 11 cases of osteoarthrosis (OA) and 10 cases of reflex sympathetic dystrophy, so called algodystrophy (AD). Mean age of the patients was respectively 44, 45 and 42 years. The sex ratio, M/F, was respectively 12/5, 6/5 and 9/1. Types of staining used were hematoxylin-eosin, Masson Trichrome, P.A.S. and Verhoeff. In counting, thick-walled and thin-walled vessels were distinguished. There was a significant reduction in the number of the thick- and thin-walled vessels, in the ON group, by comparison with the OA and AD groups. An increased number of thin-walled vessels in the AD group were also observed. Morphological study showed an abnormal frequency of fibrosis of the media in the arteries of the ON group, i.e. arteriosclerosis. These data were compared with the few other histopathological studies previously published. The authors recommend further studies in order to precise their frequency and their significance.
Arlet
J
J
Service de Rhumatologie, CHU Rangueil, Toulouse, France.
Laroche
M
M
Soler
R
R
Thiechart
M
M
Pieraggi
M T
MT
Mazières
B
B
D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D005270:Femur Head / Q000098:blood supply*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000473:pathology*; D010020:Osteonecrosis / Q000473:pathology*; D012019:Reflex Sympathetic Dystrophy / Q000473:pathology*