title: Cerebrospinal fluid thyrotropin-releasing hormone concentrations in patients with anxiety disorders.
abstract: In a study of 45 patients with anxiety disorders and 11 control subjects, mean cerebrospinal fluid (CSF) concentrations of thyrotropin-releasing hormone (TRH) were not significantly different between nonpsychiatric control subjects and those with panic disorder, generalized anxiety disorder, or obsessive-compulsive disorder. Male subjects, regardless of diagnosis, had significantly higher mean CSF concentrations of TRH than females.
authors.affiliation: Institute of Psychiatry, Medical University of South Carolina, Charleston 29425.
authors.forename: M D
authors.initials: MD
authors.lastname: Fossey
authors.forename: R B
authors.initials: RB
authors.lastname: Lydiard
authors.forename: J C
authors.initials: JC
authors.lastname: Ballenger
authors.forename: M T
authors.initials: MT
authors.lastname: Laraia
authors.forename: G
authors.initials: G
authors.lastname: Bissette
authors.forename: C B
authors.initials: CB
authors.lastname: Nemeroff
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000378:metabolism*; D001921:Brain / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D009434:Neural Pathways / Q000378:metabolism; D011569:Psychiatric Status Rating Scales; D012737:Sex Factors; D013973:Thyrotropin-Releasing Hormone / Q000032:analysis / Q000134:cerebrospinal fluid* / Q000378:metabolism*
chemical_list: D013973:Thyrotropin-Releasing Hormone