Are the WHO (1980) criteria for the 75 g oral glucose tolerance test appropriate for pregnant women?
OBJECTIVE
To determine the normal response to a 75 g glucose challenge in the context of an oral glucose tolerance test in the third trimester of pregnancy.


METHODS
Prospective observational study.


METHODS
Antenatal clinic, Kandang Kerbau Hospital, Singapore.


METHODS
Sixty-four normal pregnant women with a low risk for diabetes.


METHODS
Glucose (75 g) challenge following an overnight fast after 28 weeks of gestation.


METHODS
Venous plasma glucose levels taken before and 2 h after the glucose challenge.


RESULTS
Upper limits of normality were found to be fasting glucose 4.9 mmol/l and 2 h glucose 9.2 mmol/l.


CONCLUSIONS
The WHO (1980) criteria should not be used in pregnancy.
Cheng
L C
LC
Academic Department of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry, London.
Salmon
Y M
YM
D000328:Adult; D005260:Female; D005947:Glucose / Q000378:metabolism*; D005951:Glucose Tolerance Test / Q000592:standards*; D006801:Humans; D011247:Pregnancy / Q000378:metabolism*; D011256:Pregnancy Outcome; D011295:Prenatal Care; D012016:Reference Values; D014944:World Health Organization
D005947:Glucose