title: Portable system for continuous ex vivo measurements of lactate.
abstract: The lactate profile in serum was monitored continuously in volunteers under physical exercise on a test bicycle. The assay was operated ex vivo by means of continuous sampling through a coaxial catheter. After dialysis online, lactate was converted by means of lactate oxidase immobilized to porous glass, and the depletion of oxygen was registered by means of a Clark electrode. Good agreement between the continuous monitoring and off-line analyses was found.
authors.affiliation: Department of Biotechnology, Chemical Centre, Lund, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Håkanson
authors.forename: M
authors.initials: M
authors.lastname: Kyröläinen
authors.forename: B
authors.initials: B
authors.lastname: Mattiasson
mesh_terms: D015374:Biosensing Techniques; D002374:Catalase / Q000378:metabolism; D015444:Exercise; D006801:Humans; D007773:Lactates / Q000097:blood*; D006899:Mixed Function Oxygenases / Q000378:metabolism; D008991:Monitoring, Physiologic / Q000379:methods; D005082:Physical Exertion
chemical_list: D007773:Lactates; D006899:Mixed Function Oxygenases; D002374:Catalase; C021497:lactate 2-monooxygenase