title: Cellular motions and thermal fluctuations: the Brownian ratchet.
abstract: We present here a model for how chemical reactions generate protrusive forces by rectifying Brownian motion. This sort of energy transduction drives a number of intracellular processes, including filopodial protrusion, propulsion of the bacterium Listeria, and protein translocation.
authors.affiliation: Courant Institute of Mathematical Sciences, New York, New York 10012.
authors.forename: C S
authors.initials: CS
authors.lastname: Peskin
authors.forename: G M
authors.initials: GM
authors.lastname: Odell
authors.forename: G F
authors.initials: GF
authors.lastname: Oster
mesh_terms: D001693:Biological Transport, Active; D001696:Biomechanical Phenomena; D055592:Biophysical Phenomena; D001703:Biophysics; D002465:Cell Movement / Q000502:physiology*; D004734:Energy Metabolism; D008089:Listeria monocytogenes / Q000502:physiology; D008565:Membrane Proteins / Q000502:physiology; D008954:Models, Biological; D011108:Polymers / Q000378:metabolism; D013816:Thermodynamics
chemical_list: D008565:Membrane Proteins; D011108:Polymers