[Synthesis and biological effects of new N,N-disubstituted 5-alkyliden- and 5-aralkyliden-3-aminorhodanines].
Numerous novel N,N-disubstituted 5-alkyliden- or 5-aralkyliden-3-aminorhodanines 2 have been prepared by condensation of carbonyl compounds with 1. The effectiveness of some derivatives in an "akanthose test" with hairless mice was shown.
Hanefeld
W
W
Institut für Pharmazeutische Chemie, Philipps-Universität Marburg.
Helfrich
V
V
Jalili
M A
MA
Schlitzer
M
M
D000818:Animals; D003879:Dermatologic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D008297:Male; D051379:Mice; D008812:Mice, Hairless; D012236:Rhodanine / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000494:pharmacology; D012867:Skin / Q000033:anatomy & histology / Q000187:drug effects
D003879:Dermatologic Agents; D012236:Rhodanine
Synthese und biologische Wirksamkeit neuer N,N-disubstituierter 5-Alkyliden- bzw. 5-Aralkyliden-3-aminorhodanine.