title: Ondansetron in the treatment of intractable nausea associated with theophylline toxicity.
abstract: OBJECTIVE
  To report the efficacy of ondansetron in the treatment of a patient poisoned with theophylline.
  
  
  METHODS
  A 36-year-old man who ingested 6 g of sustained-release theophylline.
  
  
  METHODS
  Ondansetron 8 mg intravenously after clinical failure of other antiemetics.
  
  
  RESULTS
  Subjective relief of nausea within minutes, enabling the patient to tolerate multiple doses of activated charcoal and whole bowel irrigation.
  
  
  CONCLUSIONS
  Ondansetron may offer an alternative to present antiemetic therapy in the poisoned patient.
authors.affiliation: Department of Pharmacy, Department of Veterans Affairs Medical Center, San Diego, CA.
authors.forename: T A
authors.initials: TA
authors.lastname: Sage
authors.forename: W N
authors.initials: WN
authors.lastname: Jones
authors.forename: R F
authors.initials: RF
authors.lastname: Clark
mesh_terms: D000328:Adult; D003692:Delayed-Action Preparations; D006801:Humans; D008297:Male; D009325:Nausea / Q000188:drug therapy* / Q000209:etiology; D017294:Ondansetron / Q000627:therapeutic use*; D011041:Poisoning / Q000628:therapy; D013806:Theophylline / Q000008:administration & dosage / Q000506:poisoning*; D014839:Vomiting / Q000188:drug therapy / Q000209:etiology
chemical_list: D003692:Delayed-Action Preparations; D017294:Ondansetron; D013806:Theophylline