Circadian variations of superoxide dismutase activity in the rat pineal gland.
The 24 h profile of the activity of the antioxidant enzyme superoxide dismutase (SOD) in the pineal gland of rats was studied. Rhythmic analysis showed a significant 24 h rhythm with an amplitude of oscillation of 25% of the 24 h mean value, that was 100.34 +/- 1.6 U SOD (nitrite). An ultradian rhythm of 9 h was also detected. The diurnal profile of superoxide dismutase activity is discussed in relation to the oxidative metabolism of the pineal gland.
Cipolla-Neto
J
J
Department of Physiology and Biophysics, Universidade de São Paulo, Brazil.
Abdalla
D S
DS
Markus
R P
RP
Campa
A
A
D000204:Activity Cycles / Q000502:physiology; D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism; D002940:Circadian Rhythm / Q000502:physiology*; D008297:Male; D008550:Melatonin / Q000378:metabolism; D010870:Pineal Gland / Q000201:enzymology*; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000378:metabolism*
D015306:Biogenic Monoamines; D013482:Superoxide Dismutase; D008550:Melatonin