Acute pulmonary coccidioidomycosis mimicking bacterial pneumonia and septic shock: a report of two cases.
Two patients with acute pulmonary coccidioidomycosis presenting as acute bacterial pneumonia and sepsis are described. One patient died despite appropriate antifungal therapy, whereas the diagnosis in the other patient was only established after postmortem examination. In both cases, coccidioidomycosis had disseminated beyond the lungs. Factors leading to overwhelming coccidioidomycosis are discussed, and the relation of the sepsis syndrome to coccidioidomycosis is reviewed.
Lopez
A M
AM
Department of Medicine, Arizona Health Sciences Center, Tucson.
Williams
P L
PL
Ampel
N M
NM
D000208:Acute Disease; D000368:Aged; D003047:Coccidioidomycosis / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006192:Haemophilus Infections / Q000175:diagnosis / Q000382:microbiology; D006193:Haemophilus influenzae; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications / Q000175:diagnosis*; D008297:Male; D011014:Pneumonia / Q000175:diagnosis* / Q000382:microbiology; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000382:microbiology; D012772:Shock, Septic / Q000175:diagnosis* / Q000382:microbiology