title: Strangles.
abstract: The etiology, epizootiology, pathogenesis, and clinical presentation of strangles are described. Streptococcus equi, the causative organism, is highly host-adapted to Equidae and shows no antigenic variation. Protective immunity apparently is mediated by a combination of serum opsonic and nasopharyngeal mucosal humoral responses. Vaccines based on M protein or inactivated bacterial suspensions may reduce the clinical attack rate by 50%, a level of protection much lower than that produced during recovery from strangles.
authors.affiliation: Department of Veterinary Science, University of Kentucky, Lexington.
authors.forename: J F
authors.initials: JF
authors.lastname: Timoney
mesh_terms: D000818:Animals; D006734:Horse Diseases / Q000209:etiology; D006736:Horses; D012141:Respiratory Tract Infections / Q000150:complications / Q000209:etiology / Q000662:veterinary*; D013290:Streptococcal Infections / Q000150:complications / Q000209:etiology / Q000662:veterinary*