Hemiparkinsonism in a patient with primary Sjögren's syndrome. A case report and a review of the literature.
A 55-year-old woman presented with hemiparkinsonism on the left side. Clinical features suggested primary Sjögren's syndrome. Eye tests and a salivary gland biopsy confirmed this diagnosis. Magnetic resonance imaging of the brain showed distinct linear lesions of increased intensity on the T2-weighted images in the right striatum and globus pallidum. Treatment with prednisone and azathioprine did not give any improvement of the neurological symptoms. To date, hemiparkinsonism in association with primary Sjögren's syndrome has not been reported.
Visser
L H
LH
Department of Neurology, University Hospital Dijkzigt, Rotterdam, The Netherlands.
Koudstaal
P J
PJ
van de Merwe
J P
JP
D001379:Azathioprine / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging / Q000276:immunology / Q000503:physiopathology; D003342:Corpus Striatum / Q000276:immunology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D011859:Radiography; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D001379:Azathioprine; D011241:Prednisone