A study of relapses in subjects with mood disorder on lithium treatment.
In a sample of 213 mood disorder subjects on long-term lithium treatment, we analyzed the recurrence indices of relapses during the prophylactic treatment period. The differences found in the recurrence rates were due to the current age and age of onset, duration of illness and polarity of the probands. The patients with personality disorders showed the worst relapse indices and could represent a group of mood disorder subjects with a bad outcome of lithium treatment.
Gasperini
M
M
Department of Neuropsychiatric Sciences, Ospedale San Raffaele, Istituto di Ricovero e Cura a Caratiere Scientifico, University of Milan Medical School, Italy.
Scherillo
P
P
Manfredonia
M G
MG
Franchini
L
L
Smeraldi
E
E
D000375:Aging / Q000523:psychology; D001714:Bipolar Disorder / Q000188:drug therapy / Q000523:psychology; D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000188:drug therapy* / Q000517:prevention & control / Q000523:psychology; D010554:Personality Disorders / Q000188:drug therapy / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012008:Recurrence; D016896:Treatment Outcome
D008094:Lithium