[Experimental studies on the symptom-complex mechanism of pi man zao shi of dachengqi decoction].
Experiments have shown that Dachengqi Decoction can inhibit the activity of G-germs which commonly grow in the intestinal tract, inactivate the endotoxin directly in vitro, reduce the amplitude of fever caused by endotoxin injected intravenously, promote the gastric secretion and gastric retaining in rats, and increase the level of glycogen in liver. It also has some other effects. All these actions contribute to the explanation on the efficacy of Dachengqi Decoction to purge off the internal heat.
Tian
Z S
ZS
Department of Pharmacology, Tianjin ITCWM Institute of Acute Abdomenal Diseases.
Shen
C H
CH
Li
D H
DH
Liu
Y Y
YY
D000818:Animals; D001646:Bile / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D004731:Endotoxins; D004755:Enterobacteriaceae / Q000187:drug effects; D005260:Female; D005334:Fever / Q000139:chemically induced / Q000188:drug therapy; D005750:Gastric Juice / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D007958:Leukocyte Count / Q000187:drug effects; D008033:Limulus Test; D008099:Liver / Q000378:metabolism; D008297:Male; D008826:Microbial Sensitivity Tests; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal; D004731:Endotoxins; D006003:Glycogen