Vascular steal mimicking compression myelopathy in Paget's disease of bone: rapid reversal with calcitonin and systemic steroids.
Neurologic manifestations of Paget's disease of bone are primarily a result of mechanical compression on cranial nerves, spinal cord and roots. Less recognized is a myelopathy from "vascular steal" to highly vascularized and hypermetabolic pagetic bone. We describe a case of presumed ischemic myelitis in a patient with Paget's disease and aortic stenosis that was rapidly reversed with subcutaneous calcitonin and intravenous dexamethasone.
Yost
J H
JH
Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.
Spencer-Green
G
G
Krant
J D
JD
D000368:Aged; D001024:Aortic Valve Stenosis / Q000150:complications; D002116:Calcitonin / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D009187:Myelitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D010001:Osteitis Deformans / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D013116:Spinal Cord / Q000098:blood supply*
D003907:Dexamethasone; D002116:Calcitonin