[The value of diuretics in monotherapy of hypertension].
OBJECTIVE
To represent the usefulness of thiazide diuretics as monotherapy of primary hypertension.


RESULTS
Moderate doses of thiazide diuretics can produce a reduction in blood pressure equal to that of beta blockers, calcium antagonists and ACE inhibitors, and achieve an equally high response rate. The advantages and disadvantages of the specific action profile of these diuretics are described. Discussions about the reduction in cardiovascular mortality is represented and practical conclusions drawn. The specific indications for monotherapy with thiazide diuretics include systolic, diastolic and isolated systolic hypertension in the elderly hypertensive, and hypertension in NYHA III and IV cardiac insufficiency. Suggestions for their use in practice are given.
Klaus
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Leitender Arzt des KfH-Dialysezentrums Dortmund.
D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use; D001581:Benzothiadiazines; D001794:Blood Pressure / Q000187:drug effects; D004232:Diuretics; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D012307:Risk Factors; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*
D000959:Antihypertensive Agents; D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors
Stellenwert der Diuretika in der Monotherapie der Hypertonie.