Lachnumon and lachnumol a, new metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. II. Structural elucidation.
The structures of two new biologically active chlorinated metabolites isolated from submerged cultures of the ascomycete Lachnum papyraceum have been elucidated by NMR and mass spectroscopy. The compounds, lachnumon (1) and lachnumol A (2), which structurally are related with mycorrhizin A that also is produced by the fungus, contain an unusual chlorinated epoxide group.
Stadler
M
M
University of Kaiserslautern, Department of Biotechnology, Germany.
Anke
H
H
Bergquist
K E
KE
Sterner
O
O
D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification; D000969:Antinematodal Agents / Q000737:chemistry* / Q000302:isolation & purification; D001203:Ascomycota / Q000737:chemistry*; D003511:Cyclohexanols / Q000737:chemistry* / Q000302:isolation & purification; D003512:Cyclohexanones / Q000737:chemistry* / Q000302:isolation & purification; D004852:Epoxy Compounds / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy
D000935:Antifungal Agents; D000969:Antinematodal Agents; D003511:Cyclohexanols; D003512:Cyclohexanones; D004852:Epoxy Compounds; C082435:lachnumon; C082436:lachnumol A