title: Investigation of the clinical value of assessing renal size on computed tomography in autosomal dominant polycystic kidney disease.
abstract: We examined relationship between serum creatinine concentration (Scr) and renal size on CT scans on 32 occasions in 25 patients with autosomal dominant polycystic kidney disease (ADPKD). As a result, a significant correlation was observed when the Scr was less than 5 mg/dl, as shown by the correlation coefficient (r) and P values of 0.803 and 0.0001, respectively. However, these values changed to 0.482 and 0.0093, respectively when 2 cases with Scr 6.2 and 6.4 mg/dl were included, and further changed to 0.005 and 0.9775 when an additional 4 cases with Scr 7.8, 9.9, 11.1 and 20.1 mg/dl were included. Renal size is therefore thought to be a useful parameter of renal function when the Scr is less than 5 mg/dl in ADPKD, but not when the Scr exceeds 6 mg/dl, and is regarded as useless for predicting the time at which dialysis would be required.
authors.affiliation: Department of Urology, Nippon Medical School, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nishimura
authors.forename: Y
authors.initials: Y
authors.lastname: Terashima
authors.forename: Q
authors.initials: Q
authors.lastname: Shao
authors.forename: W
authors.initials: W
authors.lastname: Wong
authors.forename: S
authors.initials: S
authors.lastname: Ohba
authors.forename: Y
authors.initials: Y
authors.lastname: Fujioka
authors.forename: K
authors.initials: K
authors.lastname: Yoshida
authors.forename: M
authors.initials: M
authors.lastname: Akimoto
mesh_terms: D003404:Creatinine / Q000097:blood; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000473:pathology; D008137:Longitudinal Studies; D016891:Polycystic Kidney, Autosomal Dominant / Q000097:blood / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D012044:Regression Analysis; D014057:Tomography, X-Ray Computed
chemical_list: D003404:Creatinine