title: Penetration of lipophilic agents with multiple protonation sites into bacterial cells: tetracyclines and fluoroquinolones as examples.
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley 94720.
authors.forename: H
authors.initials: H
authors.lastname: Nikaido
authors.forename: D G
authors.initials: DG
authors.lastname: Thanassi
mesh_terms: D000890:Anti-Infective Agents / Q000493:pharmacokinetics*; D001419:Bacteria / Q000166:cytology* / Q000378:metabolism; D001665:Binding Sites; D002463:Cell Membrane Permeability; D024841:Fluoroquinolones; D008051:Lipid Bilayers / Q000378:metabolism; D013754:Tetracyclines / Q000493:pharmacokinetics*
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D008051:Lipid Bilayers; D013754:Tetracyclines