title: Chondrosarcoma treated by reimplantation of resected bone after autoclaving and supplementation with allogeneic bone matrix. A case report.
abstract: An extensive intramedullary lesion of the femur was diagnosed as a Grade I chondrosarcoma in 1986. At definitive surgery, four fifths of the femoral diaphysis were resected, autoclaved, and reimplanted. The reconstruction, after stabilization with AO plates, was supplemented with allogeneic bone matrix to induce new bone formation. No autografts were used. Despite subsequent infection and sequestration of the autoclaved tumorous segment, the reconstructed area was gradually enveloped by new bone. Three years after primary surgery, the infection persisted. The AO-plated and autoclaved sequestered bone was excised. Six years after the operation, the patient walks bearing full weight and works full time. There are no signs of tumor recurrence.
authors.affiliation: Department of Orthopaedics, Karolinska Hospital, Stockholm, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Köhler
authors.forename: A
authors.initials: A
authors.lastname: Kreicbergs
mesh_terms: D000328:Adult; D001860:Bone Plates; D016025:Bone Transplantation; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000601:surgery*; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005269:Femur / Q000601:surgery; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000628:therapy; D011183:Postoperative Complications / Q000628:therapy; D011859:Radiography; D012092:Replantation / Q000379:methods; D014184:Transplantation, Homologous