title: Infectivity, growth and distribution of preovigerous adults of Echinostoma caproni in ICR mice.
abstract: All 23 6-8-week old outbred female ICR mice, each fed 100 metacercarial cysts of Echinostoma caproni, were infected on days 2, 4, 6, and 8 postinfection (PI) with a mean of 45 worms/host. To examine worm distribution in the mouse, the small intestine was divided into five equal sections (segments 1-5 beginning with the pylorus). Worms were found mainly in segments 3 and 4 and were never found in segment 1. Mean body area of worms fixed in 10% neutral buffered formalin (NBF), hot alcohol-formalin-acetic acid (AFA) and aceto-carmine increased slowly until day 4 and then rapidly until day 8 PI. There was a significant difference in the mean body area of worms fixed in hot AFA, NBF, and aceto-carmine on all days except 4 and 6. Distinction of the ovary and ootype was apparent by day 6 and uterine cooling was observed by day 8 PI. Only 2 of 50 worms showed eggs in the uterus on day 8 PI.
authors.affiliation: Department of Biology, Lafayette College, Easton, Pennsylvania 18042.
authors.forename: P M
authors.initials: PM
authors.lastname: Manger
authors.forename: B
authors.initials: B
authors.lastname: Fried
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004449:Echinostoma / Q000254:growth & development* / Q000502:physiology; D004451:Echinostomiasis / Q000469:parasitology*; D005260:Female; D007421:Intestine, Small / Q000469:parasitology; D008297:Male; D051379:Mice