[Antiviral compounds: current approaches for development].
Recent dynamic advances of molecular biology have been discovering the specific virus functions and replication strategies that differ greatly from their host cells. These studies made it possible to design the antiviral agents which block virus replication specifically. In this paper, we review the recent approach for development of anti-HIV agents and the problems of anti-herpes compounds applied in clinical treatment.
Suzutani
T
T
Department of Microbiology, Asahikawa Medical College.
Azuma
M
M
D000212:Acyclovir / Q000627:therapeutic use; D000818:Animals; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006678:HIV / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D006561:Herpes Simplex / Q000188:drug therapy; D006801:Humans; D014158:Transcription, Genetic / Q000187:drug effects; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; D000212:Acyclovir