[Adhesion molecules and homing in inflamed synovia].
The role of adhesion molecules for lymphocyte-endothelial interactions in the synovia of rheumatoid arthritis patients was studied using the frozen section assay. Partial inhibition of lymphocyte binding to endothelium of synovial sections could be observed with antibodies against CD44, L-selectin, beta 1 and beta 2 integrins, pointing to the participation of several adhesion molecules in the regulation of lymphocyte immigration into inflamed synovia.
Fischer
C
C
Abteilung für Immunologie, Universitäts-Krankenhaus Eppendorf, Hamburg.
Thiele
H G
HG
Hamann
A
A
D001172:Arthritis, Rheumatoid / Q000276:immunology; D015815:Cell Adhesion Molecules / Q000502:physiology*; D004730:Endothelium, Vascular / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D016201:Receptors, Lymphocyte Homing / Q000502:physiology*; D013583:Synovial Membrane / Q000473:pathology*
D015815:Cell Adhesion Molecules; D016201:Receptors, Lymphocyte Homing
Adhäsionsmoleküle und Homing in entzündliche Synovia.