title: [Prostaglandin E1 bladder instillations for a patient with severe hemorrhagic cystitis after allogeneic bone marrow transplantation].
abstract: A 39-year-old female with AML (M2) underwent allogeneic bone marrow transplantation (BMT) on July 8th, 1991. The post transplantation course had been going well until day 85 post BMT, when severe hemorrhagic cystitis with right hydronephrosis and ureter stenosis developed. Adenovirus type 11 was isolated from the urine. She received instillations of prostaglandin E1 (PGE1) directly into the bladder after the appearance of clots in the urine. Complete resolution of hematuria was obtained by two courses of this treatment. PGE1 bladder instillations seem to be effective for the control of hematuria caused by severe hemorrhagic cystitis after BMT.
authors.affiliation: Second Department of Internal Medicine, Chiba University School of Medicine.
authors.forename: C
authors.initials: C
authors.lastname: Nakaseko
authors.forename: H
authors.initials: H
authors.lastname: Oh
authors.forename: K
authors.initials: K
authors.lastname: Kogure
authors.forename: A
authors.initials: A
authors.lastname: Ishii
authors.forename: H
authors.initials: H
authors.lastname: Ishii
authors.forename: T
authors.initials: T
authors.lastname: Ikegami
authors.forename: E
authors.initials: E
authors.lastname: Kawano
authors.forename: M
authors.initials: M
authors.lastname: Nishimura
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuura
authors.forename: S
authors.initials: S
authors.lastname: Morio
mesh_terms: D000258:Adenovirus Infections, Human; D000260:Adenoviruses, Human / Q000302:isolation & purification; D000283:Administration, Intravesical; D000328:Adult; D000527:Alprostadil / Q000008:administration & dosage*; D016026:Bone Marrow Transplantation; D003556:Cystitis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006470:Hemorrhage / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D014184:Transplantation, Homologous
chemical_list: D000527:Alprostadil