title: Creatine-kinase isoenzyme pattern in colonic infarction consequent to acute aortic dissection. A case report.
abstract: Bowel infarction can complicate acute aortic dissection (AAD); in that case early diagnosis, which decreases the high mortality, is often difficult. We report the case of one patient who underwent surgery for AAD and developed a colonic infarction, which was clinically manifest on the 4th postoperative day. However, bowel ischemia was suspected already 48 hours after surgery, on the basis of the suggestive CK pattern and the absence of myoglobin in plasma. Total CK activity reached the highest level only 48 hours after surgery (92,800 U/l); the peak was coincident with LDH, which increased proportionally less; CK-MM constituted 100% of total CK activity. The absence of myoglobin in plasma excluded the presence of rhabdomyolysis. We conclude that such laboratory findings suggest the occurrence of severe bowel ischemia.
authors.affiliation: Department of Anesthesiology and Resuscitation, Università Cattolica del Sacro Cuore, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Cavaliere
authors.forename: L
authors.initials: L
authors.lastname: Martinelli
authors.forename: S
authors.initials: S
authors.lastname: Guarneri
authors.forename: M
authors.initials: M
authors.lastname: Morelli
authors.forename: G F
authors.initials: GF
authors.lastname: Possati
authors.forename: R
authors.initials: R
authors.lastname: Schiavello
mesh_terms: D000208:Acute Disease; D000328:Adult; D000784:Aortic Dissection / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D004796:Clinical Enzyme Tests; D003106:Colon / Q000098:blood supply*; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D007238:Infarction / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D007527:Isoenzymes; D008297:Male; D012086:Reoperation
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase