title: [Ergotamine-induced rectal stenosis in a patient with long-term migraine].
abstract: A 36 year old woman was admitted to our hospital for treatment of a high-grade rectal stenosis of unknown origin. She had a history of migraine going back 10 years. On intensive questioning she admitted using up to 5 ergotamine-containing suppositories a day. On the basis of history and clinical investigations the rectal stenosis must be connected with the abuse of ergotamine-containing suppositories. This case demonstrates that patients with an unexplained rectal syndrome should be asked for analgetics-containing suppositories specifically. Only discontinuation of treatment in time can preserve the patient from development of a rectal stenosis. In case of a rectal stenosis surgical treatment can be avoided by means of endoscopic controlled dilatation.
authors.affiliation: I. Med. Klinik mit Poliklinik, Universität Erlangen/Nürnberg.
authors.forename: T
authors.initials: T
authors.lastname: Machnig
authors.forename: A
authors.initials: A
authors.lastname: May
authors.forename: H
authors.initials: H
authors.lastname: Steininger
authors.forename: U
authors.initials: U
authors.lastname: von Streitberg
authors.forename: E G
authors.initials: EG
authors.lastname: Hahn
authors.forename: C
authors.initials: C
authors.lastname: Ell
mesh_terms: D000328:Adult; D000632:Aminopyrine / Q000008:administration & dosage / Q000009:adverse effects*; D001706:Biopsy; D002110:Caffeine; D003113:Colonoscopy; D004106:Dilatation; D004338:Drug Combinations; D004878:Ergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005998:Glycine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007415:Intestinal Obstruction / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D007511:Ischemia / Q000139:chemically induced / Q000473:pathology; D008881:Migraine Disorders / Q000188:drug therapy*; D011437:Propylamines / Q000008:administration & dosage / Q000009:adverse effects*; D047069:Pyrazolones; D012002:Rectal Diseases / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D012007:Rectum / Q000098:blood supply; D013488:Suppositories
chemical_list: D004338:Drug Combinations; D011437:Propylamines; D047069:Pyrazolones; D013488:Suppositories; C002926:caffeine, camylofin, ergotamine, mecloxamine, propyphenazone drug combination; D000632:Aminopyrine; D002110:Caffeine; D004878:Ergotamine; D005998:Glycine
vernacular_title: Ergotamin-induzierte Rektumstenose bei einer Patientin mit langjähriger Migräne.