title: Primary plasmacytoma of generalized lymph nodes: a long survivor.
abstract: Extramedullary plasmacytomas are occasionally seen in the course of multiple myeloma; however, primary plasmacytomas are unusual. Most of the primary plasmacytomas arise in the upper respiratory system, but a plasmacytoma of the lymph nodes is very rare. A case of a 56-year-old female with primary plasmacytoma in the lower mandibular, cervical, axillary, and para-aortic lymph nodes accompanied by IgA Kappa paraproteinemia is described. After ten courses of combination chemotherapy with cyclophosphamide and prednisolone, she obtained complete response. However, 6 years later, she had a relapse of plasmacytoma in the generalized lymph nodes. She received ten treatments of melphalan-prednisolone and again obtained complete response. She has remained well without chemotherapy or recurrent signs for 9 years. It is considered that conventional chemotherapy can be useful for primary plasmacytoma of generalized lymph nodes.
authors.affiliation: Third Department of Internal Medicine, College of Medical Care and Technology, Gunma University School of Medicine, Maebashi, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Matsushima
authors.forename: H
authors.initials: H
authors.lastname: Murakami
authors.forename: J
authors.initials: J
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Sawamura
authors.forename: T
authors.initials: T
authors.lastname: Naruse
authors.forename: J
authors.initials: J
authors.lastname: Tsuchiya
mesh_terms: D005260:Female; D006801:Humans; D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains; D008198:Lymph Nodes; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications; D010954:Plasmacytoma / Q000150:complications / Q000175:diagnosis* / Q000401:mortality; D013997:Time Factors
chemical_list: D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains