title: Blood pressure variability and urinary electrolyte excretion in normotensive adults.
abstract: The principal aim of the present study was to determine the relationship of ambulatory blood pressure (BP) to urinary electrolyte excretion in normotensives. Twenty-five young adults underwent ambulatory BP and heart rate monitoring while collecting urine over 24 h. The correlations of 24 h urine sodium excretion and the ratio of sodium/potassium excretion with systolic BP in the laboratory (r = 0.12 and 0.24), ambulatory awake (r = 0.11 and 0.24), and ambulatory asleep (r = 0.24 and 0.31) settings were all in the positive direction but not significant. However, 24 h sodium excretion did correlate significantly and positively with awake and asleep ambulatory systolic (r = 0.45 and 0.41, P < .05) and diastolic (r = 0.42 and 0.43, P < .05) coefficients of variability. Thus, in normotensives on an unlimited diet, 24 h urinary sodium was more closely related to ambulatory BP variability than to BP level.
authors.affiliation: Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08903-0019.
authors.forename: M C
authors.initials: MC
authors.lastname: Ruddy
authors.forename: A
authors.initials: A
authors.lastname: Arora
authors.forename: E S
authors.initials: ES
authors.lastname: Malka
authors.forename: G B
authors.initials: GB
authors.lastname: Bialy
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D001794:Blood Pressure / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology; D003404:Creatinine / Q000652:urine; D003430:Cross-Sectional Studies; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D011188:Potassium / Q000652:urine*; D012964:Sodium / Q000652:urine*; D013223:Statistics as Topic
chemical_list: D012964:Sodium; D003404:Creatinine; D011188:Potassium