In vitro susceptibility of Haemophilus ducreyi to several antibiotics.
Haemophilus ducreyi was isolated from 59 (52%) of 113 men with a clinical diagnosis of chancroid. The following MIC50 (MIC90) values for H. ducreyi were obtained: erythromycin 0.14 (0.5) micrograms/ml, trimethoprim 0.25 (8.0) micrograms/ml, ceftriaxone 0.009 (0.14) micrograms/ml, and ciprofloxacin 0.007 (0.04) micrograms/ml. These data indicate that all isolates appear to be fully susceptible to erythromycin and the other antimicrobial agents tested, although ciprofloxacin was the most effective antibiotic.
Ismaeel
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Department of Microbiology, College of Medicine and Allied Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002443:Ceftriaxone / Q000494:pharmacology; D002602:Chancroid / Q000382:microbiology*; D002939:Ciprofloxacin / Q000494:pharmacology; D004917:Erythromycin / Q000494:pharmacology; D006191:Haemophilus ducreyi / Q000187:drug effects*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D014295:Trimethoprim / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D004917:Erythromycin; D002443:Ceftriaxone; D014295:Trimethoprim