title: [Renin-secreting renal tumor. A case report].
abstract: We reported a case of juxtaglomerular cell tumor, which excessively produced renin, resulting in secondary hypertension. A 25-year-old woman complained of headache and nausea. Hypertension and elevation of plasma renin activity were found by physical and laboratory examination. US and CT showed a space occupying lesion at upper pole of the right kidney. Angiography showed a hypovascular area at the corresponding area of the right kidney. Renin-secreting renal tumor of the right kidney was diagnosed and right nephrectomy was performed. Postoperatively, blood pressure and plasma renin activity became normalized and symptoms ameliorated. The juxtaglomerular cell tumor was pathologically confirmed and localization renin in the tumor cells was shown by immunohistochemical study. Forty one cases of juxtaglomerular cell tumor have been reported, since Robertson reported the first case. We discussed the clinical and pathological characteristics of the disease in this report.
authors.affiliation: Department of Urology, Gifu University School of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Uno
authors.forename: S
authors.initials: S
authors.lastname: Yamada
authors.forename: S
authors.initials: S
authors.lastname: Ozeki
authors.forename: M
authors.initials: M
authors.lastname: Okano
authors.forename: T
authors.initials: T
authors.lastname: Deguchi
authors.forename: M
authors.initials: M
authors.lastname: Kuriyama
authors.forename: Y
authors.initials: Y
authors.lastname: Ban
authors.forename: Y
authors.initials: Y
authors.lastname: Kawada
authors.forename: N
authors.initials: N
authors.lastname: Okumura
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology; D007606:Juxtaglomerular Apparatus; D007680:Kidney Neoplasms / Q000150:complications / Q000378:metabolism*; D012083:Renin / Q000378:metabolism*
chemical_list: D012083:Renin