title: [IR-spectroscopic study of the interaction of chromium salts with native DNA].
abstract: Infrared spectra of some unoriented films of DNA contained CrCl3, K2Cr2O7 and Cr2(SO4)3 have been obtained at relative humidities (r.h.) 0 to 93%. Chromium cations were shown to interact with phosphoric groups of DNA molecules. Cr2(SO4)3 or K2Cr2O7 content exceeds 0.1 Cr/P, the sugar-phosphate backbone of the double helix becomes irregular and nucleic bases unstacked, i.e. denaturation of DNA occurs. A very small amount of the salt, less than 0.01 Cr/P contained in DNA films prevents the conformational transition of the double helix from the B to A form induced by r.h. decreasing. The efficiency of the chromium salts in preventing the transition falls in the row: Cr2(SO4)3 > K2Cr2O7-CrCl3.
authors.forename: M M
authors.initials: MM
authors.lastname: Montrel'
authors.forename: L I
authors.initials: LI
authors.lastname: Shabarchina
authors.forename: T V
authors.initials: TV
authors.lastname: Pletneva
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Ershov
mesh_terms: D000818:Animals; D002712:Chlorides; D002857:Chromium / Q000737:chemistry*; D017608:Chromium Compounds; D004247:DNA / Q000737:chemistry*; D005399:Fishes; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D011192:Potassium Dichromate / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013431:Sulfates / Q000737:chemistry*
chemical_list: D002712:Chlorides; D017608:Chromium Compounds; D013431:Sulfates; D002857:Chromium; C040874:chromium sulfate; D004247:DNA; C017133:chromous chloride; D011192:Potassium Dichromate
vernacular_title: IK-spektroskopicheskoe izuchenie vzaimodeĭstviia soleĭ khroma s prirodnoĭ DNK.