New developments in anti-asthma drugs.
OBJECTIVE
To review the current approach to the management of bronchial asthma with particular reference to drug therapy.


METHODS
All significant English language journals were searched for current studies, particularly controlled clinical trials, in the management of asthma.


METHODS
Sixty articles were reviewed. They were selected on the basis of the known reputation of the author or the unit from which the study emanated, the place that the study has assumed in academic respiratory circles, and whether the study contributed something new to our understanding of drug therapy in asthma. Review articles from eminent scientific bodies were also analysed.


CONCLUSIONS
Asthma is an inflammatory disease and therapy must be directed towards this as well as to bronchoconstriction. Inhaled corticosteroids are the mainstay of treatment and inhaled beta-agonists are best used on an as needed basis. Regular objective assessments of patients' progress are essential, as are written, individualised action plans. The adjunctive use of other drugs is discussed and new therapies which may prove useful in the future are reviewed.
Breslin
A B
AB
Repatriation General Hospital Concord, NSW.
D000280:Administration, Inhalation; D000284:Administration, Oral; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D006801:Humans; D013256:Steroids
D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D013256:Steroids