title: Interactions between denture lining material, protein pellicles and Candida albicans.
abstract: The interactions between pellicles derived from saliva, serum, mucin and lysozyme deposited on lining material (tissue conditioner) and Candida albicans were investigated by monitoring pH changes associated with protein-free and protein-coated lining material and by ultrastructural observations of yeast colonization. No significant differences in pH reduction between culture media in contact with the protein-free, control lining materials and those coated with saliva, serum or mucin were observed after 120 h of incubation. However, scanning electron microscopy revealed that much greater numbers of the yeasts colonized the saliva- or serum-coated lining material than the lysozyme-, mucin-coated or control material. Hyphal invasion was observed in saliva-coated lining material. These results suggested that denture pellicle derived from saliva and/or serum may potentiate candidal colonization of denture lining materials.
authors.affiliation: Department of Prosthetic Dentistry, Hiroshima University School of Dentistry, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nikawa
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Nikawa
authors.forename: T
authors.initials: T
authors.lastname: Hamada
authors.forename: L P
authors.initials: LP
authors.lastname: Samaranayake
mesh_terms: D000268:Adhesiveness; D001798:Blood Proteins / Q000502:physiology; D002176:Candida albicans / Q000254:growth & development / Q000502:physiology*; D003741:Dental Deposits / Q000382:microbiology / Q000503:physiopathology*; D044622:Dental Pellicle; D003822:Denture Liners; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008689:Methacrylates / Q000737:chemistry; D009077:Mucins / Q000502:physiology; D009113:Muramidase / Q000502:physiology; D010047:Ovalbumin / Q000502:physiology; D010795:Phthalic Acids / Q000737:chemistry; D011506:Proteins / Q000502:physiology*; D012471:Salivary Proteins and Peptides / Q000502:physiology; D013499:Surface Properties
chemical_list: D001798:Blood Proteins; D008689:Methacrylates; D009077:Mucins; D010795:Phthalic Acids; D011506:Proteins; D012471:Salivary Proteins and Peptides; C073909:GC Soft-Liner; D010047:Ovalbumin; D009113:Muramidase