[Peutz-Jeghers syndrome with malignization of hamartomatous polyp].
Peutz-Jeghers syndrome is characterized by hamartomatous polyps in the gastrointestinal tract associated with mucocutaneous melanin spots; the condition is inherited in an autosomic dominant fashion. Although the hamartomatous polyps are not regarded as malignant, there is an association between the Peutz-Jeghers syndrome and the development of carcinomas of the gastrointestinal tract. Similarly, there is an increasing evidence suggesting that hamartomas can give rise to adenocarcinomas. We present a patient with Peutz-Jeghers syndrome who developed an adenocarcinoma in an hamartomatous jejunal polyp.
Rodríguez
J M
JM
II Cátedra de Cirugía, Hospital Clínico Universidad Complutense, Madrid.
Picardo
A
A
Torres
A J
AJ
García Calvo
M
M
Ortega
L
L
Martínez
S
S
Balibrea
J L
JL
D000230:Adenocarcinoma; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms; D008875:Middle Aged; D010580:Peutz-Jeghers Syndrome / Q000473:pathology*; D011230:Precancerous Conditions
Síndrome de Peutz-Jeghers con malignización de un pólipo hamartomatoso.