title: Temporal bone histopathology of open mastoidectomy cavities.
abstract: Open cavity mastoidectomy remains the principle surgical treatment of middle ear cholesteatoma in the United Kingdom. A significant proportion of mastoid cavities are prone to intermittent or continuous discharge. In this study the temporal bone histopathology of four patients who had undergone open cavity mastoidectomy is presented. Cavities were predominantly lined with stratified keratinizing squamous epithelium. Residual air cells were obliterated by fibrous tissue, with no evidence of persistent respiratory epithelium. Where inflammatory changes were found, these consisted of areas of granulation tissue in association with epithelial ulceration. Residual cholesteatoma pearls (epidermoids) were not associated with significant inflammatory changes.
authors.affiliation: Department of Otolaryngology, West Suffolk Hospital, Bury St Edmunds.
authors.forename: R
authors.initials: R
authors.lastname: Youngs
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002781:Cholesteatoma / Q000473:pathology* / Q000601:surgery; D004427:Ear Diseases / Q000601:surgery; D004432:Ear, Middle; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008416:Mastoid / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000473:pathology; D011183:Postoperative Complications / Q000473:pathology; D013701:Temporal Bone / Q000473:pathology*