[Reduced "oxidative burst" in a granulocyte subpopulation in a case of Sweet syndrome].
Oxidative burst was defective in 50% of peripheral blood neutrophils in a case of Sweet syndrome with leukemoid granulocytosis. Phagocytosis was normal. We suggest that the decreased ability to produce oxygen radicals observed in this patient might lead to a compensatory recruitment of hematopoietic growth factors. Consecutive activation, increased chemotaxis and adhesion of polymorphonuclear granulocytes might be the cause of the neutrophilic dermal infiltrate of Sweet syndrome.
Walker
U A
UA
Abteilung Rhematologie, Universität Freiburg.
Riecken
B
B
Herbst
E W
EW
Wolff-Vorbeck
G
G
Schlesier
M
M
Peter
H H
HH
D000328:Adult; D005260:Female; D006098:Granulocytes / Q000502:physiology*; D006801:Humans; D009504:Neutrophils / Q000502:physiology; D016897:Respiratory Burst; D016463:Sweet Syndrome / Q000503:physiopathology*
Verminderter "oxidative burst" in einer Granulozytensubpopulation bei einem Fall von Sweet-Syndrom.