The induction of intracellular calcium activity in cultured human myometrial smooth muscle cells.
Cells maintained in serum free medium for 24 hours were found to have a higher incidence of both spontaneous increases in intracellular calcium ([Ca2+]i) (Ca2+ spikes) and small random changes in [Ca2+]i (Ca2+ 'noise'). The spontaneous transient increases in [Ca2+]i and the Ca2+ 'noise' disappear in solutions containing nominally zero Ca2+.
Morgan
J M
JM
Department of Physiological Sciences, Medical School, University of Newcastle upon Tyne, UK.
Lynn
S
S
Gillespie
J I
JI
Greenwell
J R
JR
D000328:Adult; D002118:Calcium / Q000378:metabolism*; D002478:Cells, Cultured; D016895:Culture Media, Serum-Free; D005260:Female; D016257:Fura-2; D006801:Humans; D009130:Muscle, Smooth / Q000166:cytology / Q000378:metabolism*; D009215:Myometrium / Q000166:cytology / Q000378:metabolism*; D011247:Pregnancy
D016895:Culture Media, Serum-Free; D002118:Calcium; D016257:Fura-2