title: Lymphatic disorders in rheumatoid arthritis.
abstract: Lymphedema is a rare complication of rheumatoid arthritis (RA). Diagnosis is clinical: long-standing, painful swelling of a whole limb in association with RA. Cases described in the literature are predominantly of the upper limbs, sometimes bilateral. Diagnosis can be confirmed by biopsy of lymph nodes, lymphography, or preferably lymphoscintigraphy. The etiology of the edema is unknown. Mechanical obstruction and lymphangitis have been suggested. Pharmacological and surgical treatment of the edema have been disappointing, and treatment of the underlying RA does not improve the lymphedema. Physical treatment of the affected limb, such as massage, manual drainage techniques, light compression bandaging, and exercise, has been moderately effective.
authors.affiliation: Department of Rheumatology and Physical Medicine, Saint-Pierre Hospital, Universities of Brussels, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Joos
authors.forename: P
authors.initials: P
authors.lastname: Bourgeois
authors.forename: J P
authors.initials: JP
authors.lastname: Famaey
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D001706:Biopsy; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008209:Lymphedema / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D008220:Lymphography; D008297:Male; D011877:Radionuclide Imaging