title: Automatic determination of amylocaine and bromhexine by atomic absorption spectrometry.
abstract: An automatic method for the determination of amylocaine and bromhexine hydrochloride by atomic absorption spectrometry (AAS) is proposed. The drugs were determined indirectly by formation of reineckates, extraction into 1,2-dichloroethane and measurement of chromium in the organic phase. The chemical conditions and experimental variables influencing the performance of the flow system of the liquid-liquid extractor were established. The proposed method allows the determination of amylocaine and bromhexine at concentrations between 3 and 120 micrograms ml-1 with a relative standard deviation of 1 and 3%, respectively, even in the presence of other synthetic drugs.
authors.affiliation: Department of Analytical Chemistry, Faculty of Sciences, University of Córdoba, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Eisman
authors.forename: M
authors.initials: M
authors.lastname: Gallego
authors.forename: M
authors.initials: M
authors.lastname: Valcárcel
mesh_terms: D001322:Autoanalysis; D001565:Benzoates / Q000032:analysis*; D001964:Bromhexine / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D013054:Spectrophotometry, Atomic; D013861:Thiocyanates
chemical_list: D001565:Benzoates; D007202:Indicators and Reagents; D013861:Thiocyanates; C001818:Reinecke Salt; D001964:Bromhexine; C015677:amylocaine