title: The institutional review board as a mirror of scientific and ethical standards.
abstract: Decisions by institutional review boards (IRBs) are presumed to reflect the norms and standards of the scientific community. Such criteria have shifted as changes have occurred in experimental interventions and protocols, codes of federal regulatory agencies, norms among investigators, and expectations of participants. The tension created by shifting norms and standards raises two questions: (a) Should IRBs evaluate the scientific (e.g., design) features of the proposed research, and (b) should consistent standards be expected even in areas that are in constant flux (e.g., AIDS research)? We discuss these questions and propose a mechanism to keep IRBs abreast of emergent issues and sensitized not only to the costs of doing research but also to the costs of not doing it.
authors.affiliation: Department of Psychology, Temple University, Philadelphia, PA 19122.
authors.forename: R L
authors.initials: RL
authors.lastname: Rosnow
authors.forename: M J
authors.initials: MJ
authors.lastname: Rotheram-Borus
authors.forename: S J
authors.initials: SJ
authors.lastname: Ceci
authors.forename: P D
authors.initials: PD
authors.lastname: Blanck
authors.forename: G P
authors.initials: GP
authors.lastname: Koocher
mesh_terms: D032761:Animal Experimentation; D035841:Behavioral Research; D035843:Biomedical Research; D003657:Decision Making; D034462:Dissent and Disputes; D026724:Ethical Review; D028744:Ethics Committees, Research; D004991:Ethics, Institutional; D004995:Ethics, Professional; D005260:Female; D006126:Group Processes; D006801:Humans; D008297:Male; D033242:Minors; D035622:Parental Notification; D011367:Professional Staff Committees / Q000458:organization & administration*; D011584:Psychology; D012106:Research / Q000191:economics; D035842:Research Subjects; D018570:Risk Assessment