Compression strength of donor bone for posterior lumbar interbody fusion.
Forty-three blocks of allograft bone used clinically for posterior lumbar interbody fusion and twenty-three blocks of xenograft bone from goats and cows were tested in compression and compared with the clinical mechanical requirements of posterior lumbar interbody fusion. Variations in processing methods allowed evaluation of the effects of processing on mechanical strength. Fresh-frozen cancellous bone from Os Bone (Cleveland, OH) failed at an average load of 863 +/- 615 N. Fresh-frozen cancellous bone from the Mid American Tissue Center (Massilon, OH) failed at an average load of 3492 +/- 1720 N. Freeze-dried cancellous bone obtained from the American Red Cross failed at an average load of 1595 +/- 1031 N. Air-dried ethylene oxide sterilized cancellous bone from Os Bone failed at an average load of 1338 +/- 691 N. Air-dried ethylene oxide sterilized cancellous bone from Mid America failed at an average load of 1616 +/- 1157 N. Fresh-frozen tricortical bone from Mid America failed at an average load of 2257 +/- 1081 N. Air-dried ethylene oxide sterilized tricortical bone from Os Bone failed at an average load of 2474 +/- 1928 N. Air-dried ethylene oxide sterilized tricortical bone from Mid America failed at an average load of 2308 +/- 422 N. Bovine Surgibone from Unilab (Hillside, NJ) failed at an average load of 2967 +/- 399 N. Strength of bone in compression was not weakened by freeze drying, air drying, ethylene oxide sterilization, or by incubation at 37 degrees C for 1 week before testing.(ABSTRACT TRUNCATED AT 250 WORDS)
Brantigan
J W
JW
Cleveland Spine and Arthritis Center, Ohio.
Cunningham
B W
BW
Warden
K
K
McAfee
P C
PC
Steffee
A D
AD
D000818:Animals; D001696:Biomechanical Phenomena; D015519:Bone Density; D016025:Bone Transplantation; D001842:Bone and Bones / Q000502:physiology*; D002417:Cattle; D006041:Goats; D006801:Humans; D066298:In Vitro Techniques; D008159:Lumbar Vertebrae / Q000601:surgery*; D013123:Spinal Fusion; D014021:Tissue Preservation; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous