title: DNA repair.
abstract: Multiple DNA repair processes are required to maintain the integrity of the cellular genome. Recent advances, including elucidation of three-dimensional structures of DNA repair enzymes, and the cloning and characterization of DNA repair genes implicated in human inherited disease, have given new insights into the surprising complexity of cellular responses to DNA damage.
authors.affiliation: ICRF, Clare Hall Laboratories, South Mimms, UK.
authors.forename: D E
authors.initials: DE
authors.lastname: Barnes
authors.forename: T
authors.initials: T
authors.lastname: Lindahl
authors.forename: B
authors.initials: B
authors.lastname: Sedgwick
mesh_terms: D000818:Animals; D003057:Cockayne Syndrome / Q000235:genetics; D004247:DNA / Q000378:metabolism; D004260:DNA Repair; D006147:Guanine / Q000031:analogs & derivatives / Q000633:toxicity; D006801:Humans; D008745:Methylation; D014983:Xeroderma Pigmentosum / Q000235:genetics
chemical_list: C024829:8-hydroxyguanine; D006147:Guanine; D004247:DNA