[Lithium ion modulation of the neuronal responses evoked by monoaminergic receptor agonists].
The authors studied the action of lithium ions on the responses of rat dorsal root ganglion neurons and frog spinal motoneurons evoked by monoamine agonists using the microelectrode technique. Lithium ions reversibly inhibit the depolarizing responses of spinal sensory neurons and motoneurons evoked by activation of muscarinic choline-, alpha 1-adreno-, and 5-hydroxytryptamine2 receptors, but enhance the hyperpolarizing neuronal responses evoked by activation of 5-hidroxytryptamine1A receptors.
Abramets
I I
II
Komissarov
I V
IV
Samoĭlovich
I M
IM
D000818:Animals; D046508:Culture Techniques; D004347:Drug Interactions; D005727:Ganglia, Spinal / Q000187:drug effects / Q000502:physiology; D008094:Lithium / Q000494:pharmacology*; D018020:Lithium Compounds; D008839:Microelectrodes; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D011895:Rana ridibunda; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011950:Receptors, Cholinergic / Q000187:drug effects*; D011985:Receptors, Serotonin / Q000187:drug effects*; D013431:Sulfates / Q000494:pharmacology*
D018020:Lithium Compounds; D011941:Receptors, Adrenergic; D011950:Receptors, Cholinergic; D011985:Receptors, Serotonin; D013431:Sulfates; C054097:lithium sulfate; D008094:Lithium
Moduliatsiia ionami litiia otvetov neĭronov, vyzyvaemykh agonistami monoaminergicheskikh retseptorov.