title: Cosmetic possibilities and problems in eyelid neurofibromas.
abstract: Neurofibromatosis type 1 (NF1) is an inherited systemic disease with frequent ocular involvement. A typical alteration observed in NF1 is the eyelid plexiform neurofibroma, often associated with facial homolateral hypertrophy. In such cases, surgical cosmetic results are rather unsatisfactory, since plexiform neurofibromas classically show a non-capsulated mass, with a marked tendency to local recurrence. The techniques for a cosmetic attempt are discussed on the basis of a personal series of eyelid reconstructions in NF1. The results can be considered satisfactory in some cases, when the orbital shape is preserved and the eyelid structure has not been excessively altered by the neurofibroma; in all other cases, the cosmetic outcome is inferior to the patient's and parents' expectations. The serious problem of recurrence is however a limitation to cosmetic surgery in eyelid neurofibromas.
authors.affiliation: Department of Ophthalmology and Neurosurgery, University of Siena, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Polito
authors.forename: A
authors.initials: A
authors.lastname: Leccisotti
authors.forename: R
authors.initials: R
authors.lastname: Frezzotti
mesh_terms: D002648:Child; D002675:Child, Preschool; D005142:Eyelid Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016609:Neoplasms, Second Primary / Q000601:surgery*; D009456:Neurofibromatosis 1 / Q000000981:diagnostic imaging / Q000601:surgery*; D013518:Surgery, Plastic / Q000379:methods*; D014057:Tomography, X-Ray Computed