title: Evaluation of TSH and prolactin responses to TRH as predictors of the therapeutic effect of ECT in depression.
abstract: In a group of 42 unipolar depressed patients with melancholia the thyrotropin (TSH) and prolactin (PRL) responses to TRH were studied in relation to the clinical response to an ECT course. Patients were categorized as responders or nonresponders using as criterion a 50% reduction in the Hamilton Rating Scale for Depression score. Comparison between responders and nonresponders with respect to the TSH and PRL responses to TRH did not reveal any significant differences. Thus, TSH and PRL responses were not proved to have a predictive value for the therapeutic ECT response in melancholia.
authors.affiliation: Athens University Medical School, Psychiatric Clinic, Eginition Hospital, Greece.
authors.forename: L
authors.initials: L
authors.lastname: Lykouras
authors.forename: M
authors.initials: M
authors.lastname: Markianos
authors.forename: A
authors.initials: A
authors.lastname: Augoustides
authors.forename: Y
authors.initials: Y
authors.lastname: Papakostas
authors.forename: C
authors.initials: C
authors.lastname: Stefanis
mesh_terms: D000375:Aging / Q000523:psychology; D003866:Depressive Disorder / Q000097:blood / Q000523:psychology / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D011388:Prolactin / Q000097:blood*; D011569:Psychiatric Status Rating Scales; D013972:Thyrotropin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone
chemical_list: D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D013972:Thyrotropin