Somatostatin receptors in meningiomas: a scintigraphic study using 111In-DTPA-D-Phe-1-octreotide.
111In-octreotide (Octreoscan) planar scintigraphy was performed in 12 patients with suspected meningioma. The scan was positive in 10 patients with meningioma and negative in two patients with acoustic neurinoma assisting in the differential diagnosis. Good quality images were obtained as early as 2 h after injection and there was no increase in diagnostic quality at 24 h. No adverse effects were observed to radiopharmaceutical administration. The following conclusions are drawn: 111In-octreotide is a safe and fast test which can increase the specificity of traditional neuroimaging procedures.
Maini
C L
CL
Nuclear Medicine Department, Regina Elena National Cancer Institute, Rome, Italy.
Tofani
A
A
Sciuto
R
R
Carapella
C
C
Cioffi
R
R
Crecco
M
M
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging*; D008579:Meningioma / Q000000981:diagnostic imaging*; D008875:Middle Aged; D015282:Octreotide / Q000031:analogs & derivatives*; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D011877:Radionuclide Imaging; D011986:Receptors, Somatotropin / Q000032:analysis*
D007205:Indium Radioisotopes; D011986:Receptors, Somatotropin; C071632:SDZ 215-811; D004369:Pentetic Acid; D015282:Octreotide