Nitrogen regulation of lignin peroxidase and manganese-dependent peroxidase production is independent of carbon and manganese regulation in Phanerochaete chrysosporium.
In this study, a N-deregulated mutant (der8-5) of Phanerochaete chrysosporium was used as a tool to investigate the interrelationships between N, C, and Mn(II) regulation of LIP and MNP production in this organism. The results showed that LIP and MNP production by der8-5 was blocked in excess C medium but not in excess N medium. Furthermore, LIP and MNP production in this organism was subject to Mn(II) regulation regardless of the fact whether it is grown in low N medium or in high N medium. These and other results indicate that N regulation of LIP and MNP production in P. chrysosporium is independent of C and Mn(II) regulation.
Van der Woude
M W
MW
Department of Microbiology, Michigan State University, East Lansing 48824-1101.
Boominathan
K
K
Reddy
C A
CA
D000641:Ammonia / Q000378:metabolism; D001487:Basidiomycota / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D002244:Carbon / Q000494:pharmacology*; D003470:Culture Media; D005947:Glucose / Q000378:metabolism; D008345:Manganese / Q000494:pharmacology*; D009154:Mutation; D009584:Nitrogen / Q000494:pharmacology*; D010544:Peroxidases / Q000096:biosynthesis*; D013997:Time Factors
D003470:Culture Media; D008345:Manganese; D002244:Carbon; D000641:Ammonia; D010544:Peroxidases; C042858:lignin peroxidase; C051129:manganese peroxidase; D005947:Glucose; D009584:Nitrogen