Immunosuppression in dogs naturally infected with Babesia gibsoni.
We examined lymphoproliferative response to phytohemagglutinin and anti-parasite antibody level in dogs naturally infected with Babesia gibsoni. The dogs with subclinical B. gibsoni infection exhibited suppressed lymphocyte blastogenesis. Prominent depression of lymphocyte blastogenesis and anti-parasite antibody production was observed in dogs suffering from relapses of clinical B. gibsoni infection.
Adachi
K
K
Department of Veterinary Internal Medicine, Faculty of Agriculture, Miyazaki University, Japan.
Ueno
C
C
Makimura
S
S
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000917:Antibody Formation; D001404:Babesiosis / Q000276:immunology*; D004283:Dog Diseases; D004285:Dogs / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D007108:Immune Tolerance; D008213:Lymphocyte Activation; D008297:Male; D012016:Reference Values
D000913:Antibodies, Protozoan