Inhibition of the autoxidation of linoleic acid by phenylpropanoid glycosides from Pedicularis in micelles.
The activities of six phenylpropanoid glycosides as chain-breaking antioxidants have been studied for the autoxidation of linoleic acid in cetyl trimethylammonium bromide (CTAB) micelles at 37 degrees C. Verbascoside, isoverbascoside, echinacoside and pedicularioside A, which possess four phenolic hydroxyl groups, exhibited antioxidant activities, while cistanoside D possessing only two phenolic hydroxyl groups and permethyl verbascoside without phenolic hydroxyl group did not suppress the oxidation appreciably. The ratio of rate constants for inhibition and propagation kinh/kp and stoichiometric factor n were determined.
Zheng
R L
RL
Department of Biology, Lanzhou University, Gansu, People's Republic of China.
Wang
P F
PF
Li
J
J
Liu
Z M
ZM
Jia
Z J
ZJ
D000578:Amidines / Q000494:pharmacology; D000077286:Cetrimonium; D002593:Cetrimonium Compounds; D005960:Glucosides / Q000494:pharmacology; D006027:Glycosides / Q000494:pharmacology*; D057888:Iridoid Glucosides; D039823:Iridoids; D007700:Kinetics; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000737:chemistry / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects; D008823:Micelles; D010084:Oxidation-Reduction / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D010636:Phenols; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D059808:Polyphenols
D000578:Amidines; D000077286:Cetrimonium; D002593:Cetrimonium Compounds; D005960:Glucosides; D006027:Glycosides; D057888:Iridoid Glucosides; D039823:Iridoids; D019787:Linoleic Acid; D008041:Linoleic Acids; D008823:Micelles; D010636:Phenols; D010936:Plant Extracts; C070619:pedicularioside A; C058956:acteoside; D059808:Polyphenols; C046728:2,2'-azobis(2-amidinopropane)