title: [Pulsatile gonadotropin releasing hormone treatment following previous ovarian hyperstimulation].
abstract: Physiological follicular maturation was achieved by pulsatile gonadotrophin releasing hormone treatment in ovarian hyperstimulatory cases induced previously by other ovulation induction methods (clomiphene, clomiphene + hCG, clomiphene + hMG + hCG). The follicular development was detected by vaginal ultrasound examination (Hitachi-3000, 6.5 MHz) in 8 cycles treated with gonadotrophin releasing hormone. During the pulsatile gonadotrophin releasing hormone treatment ovulation was found in all cases and 2 pregnancies occurred. Ovarian hyperstimulation was not noticed. Physiological follicular maturation can be induced with the pulsatile administration of gonadotrophin releasing hormone after previous ovarian hyperstimulation because using this method the hypophyseal-ovarian steroid feed back mechanism remains unchanged.
authors.affiliation: Szent-Györgyi Albert Orvostudományi Egyetem, Szülészeti és Nögyógyászati Klinika, Szeged.
authors.forename: S
authors.initials: S
authors.lastname: Koloszár
authors.forename: G
authors.initials: G
authors.lastname: Bártfai
mesh_terms: D000328:Adult; D002996:Clomiphene / Q000009:adverse effects; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage*; D006801:Humans; D016471:Ovarian Hyperstimulation Syndrome / Q000139:chemically induced / Q000188:drug therapy*; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D011673:Pulsatile Flow
chemical_list: D002996:Clomiphene; D007987:Gonadotropin-Releasing Hormone
vernacular_title: Pulzatorikus gonadotropin releasing hormon kezelés elözetes ovarium hyperstimulatio után.