Effects of acetate on human immune system.
The immunopharmacologic effects of Ringer's acetate on healthy persons and cancer patients were investigated. Enhancement of in vivo polyclonal antibody production in peripheral blood lymphocytes from healthy subjects and cancer patients was elicited after the intravenous administration of 500 ml Ringer's acetate solution. Allogeneic mixed lymphocyte reaction(MLR) and natural killer(NK) activity were also increased in the majority of healthy individuals and cancer patients when administered Ringer's acetate solution but not Ringer's lactate solution.
Ishizaka
S
S
Third Department of Internal Medicine, Nara Medical University, Japan.
Kikuchi
E
E
Tsujii
T
T
D000085:Acetates / Q000494:pharmacology*; D019342:Acetic Acid; D000328:Adult; D000368:Aged; D000917:Antibody Formation / Q000187:drug effects; D000920:Antibody-Dependent Cell Cytotoxicity / Q000187:drug effects; D006801:Humans; D007107:Immune System / Q000187:drug effects*; D007552:Isotonic Solutions / Q000494:pharmacology; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000276:immunology; D000077325:Ringer's Lactate
D000085:Acetates; D007552:Isotonic Solutions; D000077325:Ringer's Lactate; C028570:Ringer's acetate; D019342:Acetic Acid