title: Mood state as a predictor of treatment outcome after in vitro fertilization/embryo transfer technology (IVF/ET).
abstract: The association between mood state and treatment outcome after In Vitro Fertilization/Embryo Transfer (IVF/ET) was assessed in a prospective sample of 330 women, of whom 113 were first time participants (inductees) and 217 were repeat cycle women (veterans). Initial evaluation of mood state indicated a significantly higher level of depression amongst veterans than inductees and a significantly greater proportion of veterans (25%) with clinically elevated depression scores compared with inductees (15%) and community norms (approx. 12%). Up to 12 months after initial assessment and after controlling for the number of treatment cycles, a significant difference was observed in the course of pregnancy over time between depressed and non-depressed women. Depressed women exhibited a lower pregnancy rate for the first treatment cycles than non-depressed women. The results and their implications are discussed.
authors.affiliation: Department of Academic Psychiatry, Royal North Shore Hospital, St Leonards, NSW, Australia.
authors.forename: P
authors.initials: P
authors.lastname: Thiering
authors.forename: J
authors.initials: J
authors.lastname: Beaurepaire
authors.forename: M
authors.initials: M
authors.lastname: Jones
authors.forename: D
authors.initials: D
authors.lastname: Saunders
authors.forename: C
authors.initials: C
authors.lastname: Tennant
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000523:psychology*; D001007:Anxiety / Q000523:psychology; D003863:Depression / Q000523:psychology; D004624:Embryo Transfer / Q000523:psychology*; D005260:Female; D005307:Fertilization in Vitro; D005500:Follow-Up Studies; D006801:Humans; D007247:Infertility, Female / Q000523:psychology* / Q000628:therapy; D010555:Personality Inventory; D011247:Pregnancy / Q000523:psychology