[Effects of water hardness and salt intake on the formation and disappearance of experimental atherosclerosis].
The present study examined the effects of water-hardness and salt-intake, both of which were higher in north China than in the south, on experimental atherosclerosis in quail. At the end of the experiment atherosclerotic lesions in the high-salt groups were found to be more marked than those in the low-salt groups. No significant difference in total cholesterol value was found between the two groups. There was a significant positive correlation between the degree of atherosclerosis and serum-sodium value (r = 0.501, P < 0.01). There was no difference in all values between hard-water or soft-water groups. Our study suggested that high salt-intake stimulated and enhanced the formation of atherosclerosis while it delayed and impeded its disappearance, but water-hardness did not.
Zhang
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ST
Department of Cardioligy, Shandong Academy of Medical Science, Ji'nan.
D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology*; D002118:Calcium / Q000032:analysis; D008274:Magnesium / Q000032:analysis; D011784:Quail; D012965:Sodium Chloride / Q000009:adverse effects*; D012982:Sodium, Dietary / Q000008:administration & dosage*; D014881:Water Supply / Q000032:analysis
D012982:Sodium, Dietary; D012965:Sodium Chloride; D008274:Magnesium; D002118:Calcium