title: Serologic response to Helicobacter pylori among children and teenagers in northern Chile.
abstract: The serologic response to Helicobacter pylori was determined in 388 children and teenagers living in Iquique, Chile by using an IgG enzyme-linked immunosorbent assay. Serum antibody levels, as measured by optical density, correlated strongly with age. Increases in the mean antibody level were seen primarily after age five, with rates of seropositivity increasing to > or = 70% among teenagers. The reasons for this age-related pattern of acquisition of infection remain to be determined.
authors.affiliation: Program in Comparative Medicine, University of Maryland School of Medicine, Baltimore.
authors.forename: R G
authors.initials: RG
authors.lastname: Russell
authors.forename: S S
authors.initials: SS
authors.lastname: Wasserman
authors.forename: J M
authors.initials: JM
authors.lastname: O'Donnoghue
authors.forename: D N
authors.initials: DN
authors.lastname: Taylor
authors.forename: J
authors.initials: J
authors.lastname: Boslego
authors.forename: J G
authors.initials: JG
authors.lastname: Moreno
authors.forename: R J
authors.initials: RJ
authors.lastname: Hopkins
authors.forename: L J
authors.initials: LJ
authors.lastname: DeTolla
authors.forename: J G
authors.initials: JG
authors.lastname: Morris
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000704:Analysis of Variance; D000907:Antibodies, Bacterial / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D002677:Chile / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D008297:Male; D015995:Prevalence
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G