[Effect of bacteria on chemotaxis of peripheral blood lymphocytes from nonatopic asthmatics].
The chemotactic response of peripheral blood lymphocytes from nonatopic asthmatics and healthy subjects in the gradients of various bacterial strains obtained from the airways of the asthmatic patients was investigated. The dominant autologous strains were found to be effective chemoattractants for lymphocytes form the asthmatics. However, none of the bacterial strains investigated in this study induced increased motility of lymphocytes from healthy subjects. These findings might explain the mechanisms of the accumulation of lymphocytes in the airways of nonatopic asthmatics.
Zak-Nejmark
T
T
Katedry i Kliniki Chorób Wewnetrznych i Alergologii AM, Wrocławiu.
Małolepszy
J
J
Kraus-Filarska
M
M
Nadobna
G
G
Jutel
M
M
Stankiewicz
M
M
D000328:Adult; D001249:Asthma / Q000276:immunology* / Q000382:microbiology; D001419:Bacteria / Q000276:immunology*; D002464:Cell Migration Inhibition; D002634:Chemotaxis, Leukocyte / Q000276:immunology*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008297:Male
Wpływ bakterii na chemotaksje limfocytów krwi obwodowej w astmie nieatopowej.