title: [Chromosome loss in metaphase of peripheral blood lymphocytes in patients with Turner's syndrome before treatment and at the time of substitution therapy].
abstract: Chromosome loss in metaphases of 72 hours human peripheral blood lymphocyte cultures, at the Turner syndrome (45,X, and 46,X,izo(Xq),) patients is three times higher than in lymphocyte cultures of healthy women. Hormonal therapy decreases frequency of chromosome loss.
authors.affiliation: Zakładu Genetyki i Patomorfologii PAM, Szczecinie.
authors.forename: J
authors.initials: J
authors.lastname: Gronwald
authors.forename: S
authors.initials: S
authors.lastname: Zajaczek
authors.forename: E
authors.initials: E
authors.lastname: Sowińska
authors.forename: I
authors.initials: I
authors.lastname: Rzepka-Gorska
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002872:Chromosome Deletion; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000166:cytology*; D008677:Metaphase / Q000235:genetics; D012016:Reference Values; D014424:Turner Syndrome / Q000235:genetics* / Q000628:therapy*
vernacular_title: Utrata chromosomów w metafazach limfocytów krwi obwodowej chorych z zespołem Turnera przed leczeniem i w trakcie hormonalnej substytucji.