title: [Scleromyxedema associated with myopathy].
abstract: We describe a 45 year-old man, with scleromyxedema associated to systemic manifestations, including myopathy. After 6 years of dermatologic manifestations, muscular weakness, with proximal predominance resulting in incapacity, was established. Corticosteroids plus cyclophosphamide treatment suppressed muscular symptomatology, and a second biopsy was normal. The common association between scleromyxedema and myopathy and other systemic alterations suggest that this entity should probably be considered as a systemic disease instead as a skin disease.
authors.affiliation: Servicio de Neurología, Hospital La Fe, Valencia.
authors.forename: J
authors.initials: J
authors.lastname: Catalá
authors.forename: J
authors.initials: J
authors.lastname: López-Aldeguer
authors.forename: J J
authors.initials: JJ
authors.lastname: Vílchez
authors.forename: M
authors.initials: M
authors.lastname: Chirivella
authors.forename: M T
authors.initials: MT
authors.lastname: Catalá
mesh_terms: D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D008010:Lichen Planus / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000150:complications* / Q000188:drug therapy; D009230:Myxedema / Q000150:complications* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D003520:Cyclophosphamide; D011241:Prednisone
vernacular_title: Escleromixedema asociado a miopatía.