Discovery of inhibitors of the 5-lipoxygenase activating protein (flap).
Young
R N
RN
Merck Frosst Centre for Therapeutic Research, Pointe Claire-Dorval, Quebec, Canada.
Gillard
J W
JW
Hutchinson
J H
JH
Léger
S
S
Prasit
P
P
D058927:5-Lipoxygenase-Activating Proteins; D000818:Animals; D002352:Carrier Proteins / Q000037:antagonists & inhibitors*; D006801:Humans; D007211:Indoles / Q000737:chemistry / Q000494:pharmacology; D015289:Leukotrienes / Q000096:biosynthesis; D016859:Lipoxygenase Inhibitors; D008565:Membrane Proteins / Q000037:antagonists & inhibitors*; D051381:Rats; D013329:Structure-Activity Relationship; D002722:Chlorobenzenes
D058927:5-Lipoxygenase-Activating Proteins; D002352:Carrier Proteins; D007211:Indoles; D015289:Leukotrienes; D016859:Lipoxygenase Inhibitors; D008565:Membrane Proteins; C548592:ALOX5AP protein, human; C060893:MK-886; D002722:Chlorobenzenes