Intra-abdominal desmoplastic small round cell tumor.
A rarely encountered but distinctive type of aggressive malignant tumor of childhood and adolescence has been recently described as occurring predominantly or exclusively intrabdominally. It is characterized by a generally diffuse pattern of growth of small cells with hyperchromatic nuclei, scanty cytoplasm, patchy epithelial differentiation, immunohistochemical co-expression of keratin and desmin intermediate filaments and a focal but pronounced desmoplastic stromal component. It is regarded as yet another variant in the group of small round cell tumors (SRCT) of infancy and childhood. This case report of a mass in the greater omentum of a 15 yr-old girl adds to the 33 cases already described in the English literature.
Yeoh
G
G
Department of Anatomical Pathology, Royal Prince Alfred Hospital, Sydney.
Russell
P
P
Wills
E J
EJ
Fleming
S
S
D000293:Adolescent; D005260:Female; D006801:Humans; D007381:Intermediate Filament Proteins / Q000032:analysis; D008854:Microscopy, Electron; D009852:Omentum / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000737:chemistry / Q000473:pathology / Q000648:ultrastructure*
D007381:Intermediate Filament Proteins