title: Synthesis and characterization of human neutrophil elastase inhibitors derived from aromatic esters of phenylalkanoic acids.
authors.affiliation: Cortech, Inc., Denver, CO 80221.
authors.forename: G P
authors.initials: GP
authors.lastname: Kirschenheuter
authors.forename: J
authors.initials: J
authors.lastname: Oleksyszyn
authors.forename: L W
authors.initials: LW
authors.lastname: Spruce
authors.forename: M
authors.initials: M
authors.lastname: Wieczorek
authors.forename: T M
authors.initials: TM
authors.lastname: Kloppel
authors.forename: S R
authors.initials: SR
authors.lastname: Simon
authors.forename: J C
authors.initials: JC
authors.lastname: Cheronis
mesh_terms: D010450:Endopeptidases / Q000378:metabolism; D005109:Extracellular Matrix / Q000201:enzymology; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D019272:Leukocyte Elastase; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors*; D010654:Phenylbutyrates / Q000138:chemical synthesis / Q000494:pharmacology*; D011480:Protease Inhibitors / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D010654:Phenylbutyrates; D011480:Protease Inhibitors; D010450:Endopeptidases; D010196:Pancreatic Elastase; D019272:Leukocyte Elastase