DNA diagnosis for the detection of sickle hemoglobinopathies.
At this time, the sole generally accepted use for DNA diagnosis in the hemoglobinopathies is for the prenatal detection of disease, which can be identified by these means early in the first trimester of pregnancy. By ascertaining genotype rather than phenotype, the confusion that results from diagnostic errors should be diminished. DNA diagnostics are the future of all genetic disease detection and this future will soon be upon us.
Steinberg
M H
MH
VA Medical Center, Jackson, MS 39216.
D004247:DNA / Q000032:analysis*; D003951:Diagnostic Errors; D005240:Feasibility Studies; D006451:Hemoglobin, Sickle; D006453:Hemoglobinopathies / Q000175:diagnosis* / Q000235:genetics; D006455:Hemoglobins, Abnormal; D006801:Humans; D008722:Methods
D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal; D004247:DNA