title: Hemodynamic parameters of stage 20 to stage 35 chick embryo.
abstract: Hemodynamic parameters of the chick embryo from stage 20 (3 d of a 21-d incubation) up to stage 35 (8 d) are described. Normal values of dorsal aortic flow velocity wave forms were measured with a 20-MHz directional-pulsed Doppler velocity meter that was validated to be accurate above 5 mm/s. An analysis of variance was carried out for each of the flow velocity parameters. The correlation coefficient that represents the reproducibility was satisfactory (r > 0.90). There was a 17-fold rise in mean dorsal aortic blood flow (mm3/s). Heart rate doubled from 123 +/- 12 to 239 +/- 8 bpm, and stroke volume increased from 0.14 +/- 0.08 to 1.28 +/- 0.55 mm3. A stage-related rise was seen in peak systolic and mean velocities and peak acceleration. These data may serve as a basis for flow velocity wave form investigation and interpretation in developmental stages of cardiac malformations.
authors.affiliation: Department of Obstetrics and Gynaecology, Academic Hospital Rotterdam, Dijkzigt, Erasmus University, The Netherlands.
authors.forename: M L
authors.initials: ML
authors.lastname: Broekhuizen
authors.forename: F
authors.initials: F
authors.lastname: Mast
authors.forename: P C
authors.initials: PC
authors.lastname: Struijk
authors.forename: W
authors.initials: W
authors.lastname: van der Bie
authors.forename: P G
authors.initials: PG
authors.lastname: Mulder
authors.forename: A C
authors.initials: AC
authors.lastname: Gittenberger-de Groot
authors.forename: J W
authors.initials: JW
authors.lastname: Wladimiroff
mesh_terms: D000818:Animals; D001011:Aorta / Q000196:embryology / Q000502:physiology; D002642:Chick Embryo / Q000502:physiology*; D006321:Heart / Q000196:embryology / Q000502:physiology; D006439:Hemodynamics; D015203:Reproducibility of Results; D013997:Time Factors