Necrobiotic xanthogranuloma without periorbital lesions.
Cutaneous necrobiotic xanthogranuloma is rare and closely resembles widespread necrobiosis lipoidica. It is important to recognize this skin disorder because of its strong association with paraproteinemia and, in some cases, with a hematologic malignancy. We describe two patients with necrobiotic xanthogranuloma who are unusual in that they had no periorbital involvement, a feature previously believed to be diagnostic of this condition.
McGregor
J M
JM
Department of Dermatology, Guy's Hospital, London, United Kingdom.
Miller
J
J
Smith
N P
NP
Hay
R J
RJ
D000368:Aged; D001706:Biopsy; D005260:Female; D006099:Granuloma / Q000473:pathology*; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology*; D014973:Xanthomatosis / Q000473:pathology*