title: Familial subungual keratoacanthoma in association with ectodermal dysplasia.
abstract: Described is the first report of familial SUKA, occurring in two of three sisters with ectodermal dysplasia, a rare, hereditary disorder involving ectodermally derived organ systems. Although rare, SUKA should be considered when assessing rapidly growing nailbed lesions. Differentiation from subungual squamous cell carcinoma is essential. Tumor excision and curettage and close postoperative follow-up are recommended, with conservative amputation reserved for tumor recurrences. If the diagnosis of SUKA is confirmed in a female, an association with ectodermal dysplasia should be sought.
authors.affiliation: Division of Plastic Surgery, State University of New York Health Science Center Brooklyn.
authors.forename: B T
authors.initials: BT
authors.lastname: Shatkin
authors.forename: J G
authors.initials: JG
authors.lastname: Hunter
authors.forename: I C
authors.initials: IC
authors.lastname: Song
mesh_terms: D000328:Adult; D004476:Ectodermal Dysplasia / Q000150:complications* / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007184:Incontinentia Pigmenti / Q000150:complications / Q000235:genetics / Q000473:pathology; D007636:Keratoacanthoma / Q000150:complications* / Q000235:genetics* / Q000473:pathology; D009260:Nail Diseases / Q000150:complications / Q000235:genetics* / Q000473:pathology