title: Stimulation causing the double effect as in dyspraxia, a universal mechanism of disease, and auto-electrocution, the fatal factor.
abstract: Almost every action in the body involves the nervous system which uses electricity for its speed and versatility. Operating and controlling muscular activity is a major function of the nervous system. Muscles are paired so every normal contraction requires a reciprocal relaxation of its doppelganger (Newton said 'Equal and opposite'). Minor failures of co-operation, i.e. neuromuscular dysfunction make common survivable diseases. Multiple and major stimuli can create chaotic conflicts within these couplings and lead to fatalities. Excessive, abnormal, even ordinary stimulation will cause the (irritable?) partner(s) which should relax also to contract. Thus function is impaired or impossible. In the limbs faulty neuromuscular co-ordination is obvious as stiffness, Parkinson's Disease, Erb's Palsy etc. Less evident, it is even more important in the cardiovascular, gastrointestinal, genitourinary and respiratory systems.
authors.forename: M G
authors.initials: MG
authors.lastname: Baggot
mesh_terms: D003645:Death, Sudden / Q000209:etiology; D004558:Electric Stimulation; D006801:Humans; D008954:Models, Biological; D009468:Neuromuscular Diseases / Q000209:etiology*; D009469:Neuromuscular Junction / Q000503:physiopathology