[Triploidy as a cause of failure in human reproduction].
Triploidy is a frequent chromosomal abnormality found in 12% of all spontaneous first trimester abortions. Triploidy can result from various mechanisms: failure of segregation during meiosis I or II leads to the formation of gametes with an extra haploid set of chromosomes or abnormally fertilization by two spermatozoa. The authors presents physiological mechanism which prevent polyspermic fertilization, the morphological pictures of triploid early embryos. After implantation of triploid embryos partial embryonal hydatidiform moles develops. Now the possibility of the prevention and treatment of triploid in humans are very limited.
Wołczyński
S
S
Zakładu Endokrynologii Ginekologicznej, Instytutu Połoznictwa i Chorób Kobiecych w Białymstoku.
Kulikowski
M
M
Szamatowicz
M
M
D000022:Abortion, Spontaneous / Q000235:genetics*; D002869:Chromosome Aberrations / Q000517:prevention & control; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D011003:Ploidies; D011247:Pregnancy
Triploidia jako przyczyna niepowodzeń w rozrodzie człowieka.