[Degradation of succinylcholine chloride].
Quantitative thin-layer chormatographic method has been developed for the investigation of the degradation of injection formulations containing succinylcholinium chloride. The method is based on the denistometric determination of the main degradation product, choline at 430 nm after visualization with iodine vapour. The stability of the injection was investigated under various storage conditions and it has been stated that considerable decomposition takes place during as short a period as one week.
Németh
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G
Országos Gyógyszerészeti Intézet, Budapest.
Török
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I
Paál
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T
D002855:Chromatography, Thin Layer; D004355:Drug Stability; D007202:Indicators and Reagents; D007267:Injections; D007700:Kinetics; D013390:Succinylcholine / Q000008:administration & dosage / Q000737:chemistry*
D007202:Indicators and Reagents; D013390:Succinylcholine
Szukcinil-kolinium-klorid injekció bomlásának vizsgálata.