[Functions of antioncogene products].
Inactivation of antioncogenes result in the generation of tumor cells. Recent progress in molecular biology of antioncogenes enabled us to study the function of the products of RB, WT, p53, NF1, DCC, APC and MCC genes. Analyses of the function of these proteins will give us an insight into the mechanisms of cell transformation.
Akiyama
T
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Dept. of Oncogene Research, Osaka University.
D025601:Adenomatous Polyposis Coli Protein; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000502:physiology; D016147:Genes, Tumor Suppressor; D006801:Humans; D009363:Neoplasm Proteins / Q000737:chemistry / Q000502:physiology; D025542:Neurofibromin 1; D011506:Proteins / Q000737:chemistry / Q000502:physiology; D016160:Retinoblastoma Protein / Q000737:chemistry / Q000502:physiology*; D014170:Transformation, Genetic; D016159:Tumor Suppressor Protein p53 / Q000737:chemistry / Q000502:physiology*; D025721:WT1 Proteins
D025601:Adenomatous Polyposis Coli Protein; D004268:DNA-Binding Proteins; D009363:Neoplasm Proteins; D025542:Neurofibromin 1; D011506:Proteins; D016160:Retinoblastoma Protein; D016159:Tumor Suppressor Protein p53; D025721:WT1 Proteins