Cerebrovascular autoregulation may be the probable mechanism responsible for fentanyl- and sufentanil-induced increases in intracranial pressure in patients with head trauma.
DeLima
L G
LG
D001921:Brain / Q000098:blood supply; D002560:Cerebrovascular Circulation / Q000187:drug effects* / Q000502:physiology*; D006259:Craniocerebral Trauma / Q000188:drug therapy* / Q000503:physiopathology; D005283:Fentanyl / Q000009:adverse effects* / Q000494:pharmacology; D006801:Humans; D007427:Intracranial Pressure / Q000187:drug effects*; D017409:Sufentanil / Q000009:adverse effects* / Q000494:pharmacology; D014661:Vasoconstriction / Q000187:drug effects / Q000502:physiology
D017409:Sufentanil; D005283:Fentanyl