[Monoxycarbogenic reaction of chloral: application to the obtention of carboxyhemoglobin and to its determination in blood].
Carbon monoxide CO, generated from chloral (10(-2) M) in a dilution of hemochrome (pH 13), turns the solution of hemochrome into a solution of carboxyhemoglobin. The spectrum of this solution is identical to the one obtained after bubbling with CO. The reaction is fast and makes it possible to determine the percentage of carboxyhemoglobinemia in whole blood.
Malbosc
R
R
Service de Toxicologie, Faculté de Pharmacie, Toulouse, France.
Broqua
C
C
Tufenkji
A E
AE
Bergeal
M F
MF
Mabon
N
N
D002248:Carbon Monoxide / Q000138:chemical synthesis; D002263:Carboxyhemoglobin / Q000493:pharmacokinetics*; D002697:Chloral Hydrate / Q000031:analogs & derivatives* / Q000494:pharmacology; D013053:Spectrophotometry / Q000379:methods
D002697:Chloral Hydrate; D002248:Carbon Monoxide; D002263:Carboxyhemoglobin; C021100:trichloroacetaldehyde
La réaction monoxycarbogénique du chloral: application à l'obtention de la carboxyhémoglobine et à son dosage dans le sang.