Sensitivity of culture compared with that of polymerase chain reaction for detection of Helicobacter pylori from antral biopsy samples.
Polymerase chain reaction (PCR) was used to test the sensitivity of standard bacteriological culture of Helicobacter pylori. The tests were concordant in 97% of cases. PCR did not detect more treatment failures after triple treatment than did the standard culture method. In the present study, culture was as sensitive as PCR for the detection of H. pylori.
van Zwet
A A
AA
Regional Public Health Laboratory, Groningen, The Netherlands.
Thijs
J C
JC
Kooistra-Smid
A M
AM
Schirm
J
J
Snijder
J A
JA
D001431:Bacteriological Techniques / Q000706:statistics & numerical data; D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics; D005069:Evaluation Studies as Topic; D005756:Gastritis / Q000175:diagnosis / Q000382:microbiology; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000175:diagnosis / Q000382:microbiology; D016480:Helicobacter pylori / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000706:statistics & numerical data; D011706:Pyloric Antrum / Q000382:microbiology; D012680:Sensitivity and Specificity
D004269:DNA, Bacterial