title: Intimate relationships of the large and the small subunits of all nickel hydrogenases with two nuclear-encoded subunits of mitochondrial NADH: ubiquinone oxidoreductase.
abstract: The sequence pattern CxxCxnGxCxxxGxmGCPP, thus far found in the small subunits from 21 different nickel hydrogenases, appears also to be present in the PSST polypeptide from NADH:ubiquinone oxidoreductase (Complex I) of beef-heart mitochondria. There is only one difference: the first cysteine residue is a leucine in the PSST subunit. The large nickel-binding subunit of nickel hydrogenases shows a surprising homology with the 49 kDa subunit of mitochondrial Complex I.
authors.affiliation: E.C. Slater Institute, BioCentrum, University of Amsterdam, The Netherlands.
authors.forename: S P
authors.initials: SP
authors.lastname: Albracht
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001419:Bacteria / Q000201:enzymology; D002417:Cattle; D008929:Mitochondria, Heart / Q000201:enzymology*; D008969:Molecular Sequence Data; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry
chemical_list: D009532:Nickel; D016660:NAD(P)H Dehydrogenase (Quinone)