title: Proprioceptive responses under rising and falling BACs: a test of the Mellanby effect.
abstract: This study examined proprioceptive responses under equivalent rising and falling blood alcohol concentrations (BAC), using a repeated-measures design. Seven volunteer subjects, 21 to 35 years of age, participated in the study. After alcohol consumption, BAC readings were obtained every 5 minutes, and the proprioceptive responses were measured at the following BAC levels (in %): 0 (baseline), rising 0.05, 0.075, 0.1, falling 0.075, and 0.05. The analysis focused on the comparisons of these measures at the equivalent rising and falling 0.05% and at the 0.075% BACs. Results showed that the proprioceptive response was less accurate during the rising than the falling BACs.
authors.affiliation: Area of Health and Human Performance Studies, University of Alabama, Tuscaloosa 35487-0312.
authors.forename: M Q
authors.initials: MQ
authors.lastname: Wang
authors.forename: M E
authors.initials: ME
authors.lastname: Nicholson
authors.forename: B S
authors.initials: BS
authors.lastname: Mahoney
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.forename: M A
authors.initials: MA
authors.lastname: Perko
mesh_terms: D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects*; D000431:Ethanol / Q000097:blood*; D006801:Humans; D007858:Learning / Q000502:physiology; D008297:Male; D009048:Motor Skills / Q000502:physiology*; D011434:Proprioception / Q000502:physiology*
chemical_list: D000431:Ethanol