title: Melanoma and occupation: results of a case-control study in The Netherlands.
abstract: Several studies have reported excesses of risk of melanoma in specific industries. Data from a case-control study in The Netherlands, including 140 cases with a cutaneous melanoma and 181 controls with other types of malignancy, were used to evaluate whether the reported associations with these specific industries could be reproduced. Adjustment for characteristics of pigmentation and exposure to sunlight was made. Increased risks of cutaneous melanoma were found for subjects who had ever worked in the electronics industry (odds ratio (OR) = 2.03, 95% confidence interval (95% CI) 0.63-6.62), in the metal industry (OR = 2.61, 95% CI 0.96-7.10), and in the transport and communication branch (OR = 1.92, 95% CI 0.84-4.35). These ORs were adjusted for age, sex, education, hair colour, tendency to burn, freckling, and exposure to sunlight. No increased risks were seen for workers in the chemical industry, the textile industry, and among health care workers. Analyses according to duration and latency of exposure did not give consistent results, but existing patterns may be obscured by the imprecision of the estimates.
authors.affiliation: Department of Medical Informatics and Epidemiology, University of Nijmegen, The Netherlands.
authors.forename: P J
authors.initials: PJ
authors.lastname: Nelemans
authors.forename: R
authors.initials: R
authors.lastname: Scholte
authors.forename: H
authors.initials: H
authors.lastname: Groenendal
authors.forename: L A
authors.initials: LA
authors.lastname: Kiemeney
authors.forename: F H
authors.initials: FH
authors.lastname: Rampen
authors.forename: D J
authors.initials: DJ
authors.lastname: Ruiter
authors.forename: A L
authors.initials: AL
authors.lastname: Verbeek
mesh_terms: D000367:Age Factors; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007221:Industry; D008297:Male; D008545:Melanoma / Q000209:etiology*; D009784:Occupational Diseases / Q000209:etiology*; D009790:Occupations; D016017:Odds Ratio; D012307:Risk Factors; D012737:Sex Factors; D012878:Skin Neoplasms / Q000209:etiology*; D013997:Time Factors