[Lymphocyte subpopulation in asthmatic children with chronic bronchial obstruction].
Lymphocyte subpopulations in peripheral blood were examined in asthmatic children, using fluorescent monoclonal antibodies. The patients were divided into three groups: Group I, no attack (FEV1.0% > or = 80% group), Group II, no attack (FEV1.0% < 80% group) and Group III, asthmatic attack group. The percentage of CD3HLADR/CD3 in the Group II and Group III were 5.58 +/- 3.59 and 5.44 +/- 4.34, respectively, which were significantly higher than that in the Group I subjects (2.70 +/- 2.17). This finding suggests that the patients with long lasting bronchial obstruction may have chronic inflammation in the airway even in the remission stage of asthmatic attacks.
Murayama
N
N
Department of Pediatric Allergy, Osaka Prefectural Habikino Hospital.
Kameda
M
M
Takamatsu
I
I
Inoue
T
T
Doi
S
S
Toyoshima
K
K
D000293:Adolescent; D001249:Asthma / Q000150:complications / Q000276:immunology*; D002648:Child; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000209:etiology / Q000276:immunology*; D008213:Lymphocyte Activation; D016131:Lymphocyte Subsets; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology
D006684:HLA-DR Antigens