Immunological properties of ribosomal proteins from Mycobacterium bovis BCG.
Two proteins with molecular mass 65 kDa, a heat shock protein, and an S1-like protein were found in a 30S ribosomal subunit from Mycobacterium bovis BCG. The 17-kDa protein in the 30S subunit was homologous to alpha-crystallin heat shock protein, and the 16-kDa protein in the 50S subunit was homologous to the L7/L12 protein. The latter provoked a strong delayed-type hypersensitivity reaction in the sensitized guinea pigs. The GroES-like protein (12 kDa) loosely associated with ribosomes.
Tantimavanich
S
S
Department of Clinical Microbiology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand.
Nagai
S
S
Nomaguchi
H
H
Kinomoto
M
M
Ohara
N
N
Yamada
T
T
D000818:Animals; D001426:Bacterial Proteins / Q000276:immunology*; D006168:Guinea Pigs; D006360:Heat-Shock Proteins / Q000276:immunology*; D006968:Hypersensitivity, Delayed; D009163:Mycobacterium bovis / Q000276:immunology*; D012269:Ribosomal Proteins / Q000276:immunology*; D012882:Skin Tests
D001426:Bacterial Proteins; D006360:Heat-Shock Proteins; D012269:Ribosomal Proteins