title: Frequency and antimicrobial susceptibility of clinical isolates of enterococci.
abstract: A study was performed to determine the frequency and antimicrobial susceptibility of Enterococcus species in clinical specimens. Of 943 aesculin-positive isolates, 873 (92%) were identified as enterococci (737 Enterococcus faecalis, 129 Enterococcus faecium and 7 other Enterococcus species). High-level resistance to gentamicin was found in 15.2% of Enterococcus faecalis, but not in Enterococcus faecium; 58% of Enterococcus faecium were resistant to gentamicin at a concentration of 64 mg/l. None of the isolates were shown to possess vancomycin resistance.
authors.affiliation: Department of Medical Microbiology, Royal London Hospital Trust, Whitechapel, UK.
authors.forename: M
authors.initials: M
authors.lastname: Guiney
authors.forename: G
authors.initials: G
authors.lastname: Urwin
mesh_terms: D004352:Drug Resistance, Microbial; D016983:Enterococcus / Q000145:classification / Q000187:drug effects*; D013293:Enterococcus faecalis / Q000145:classification / Q000187:drug effects; D016984:Enterococcus faecium / Q000145:classification / Q000187:drug effects; D005839:Gentamicins / Q000494:pharmacology* / Q000627:therapeutic use; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D014640:Vancomycin / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D005839:Gentamicins; D014640:Vancomycin