[A double ambulatory product (blood pressure and heart rate), mild arterial hypertension and left ventricular hypertrophy].
OBJECTIVE
Analysis of the different ambulatory blood pressure monitoring derived parameters in terms of cardiac structural repercussion, in patients with isolated systolic and mild systolic-diastolic hypertension.


METHODS
Prospective study involving simultaneously the two-dimensional echocardiographic technique and the ambulatory blood pressure monitoring method.


METHODS
Out patients regularly observed in the Cardiology Department of Egas Moniz Hospital in Lisbon, were included in our study.


METHODS
We studied 50 hypertensive patients who fulfilled the inclusion criteria of our study (Group H) and 20 subjects who were the normal aged matched population (Group N). through ambulatory blood pressure monitoring, in each individual of these two groups, we considered the mean values of daily systolic blood and diastolic blood pressure, heart rate and ambulatory heart rate blood pressure product. Through two-dimensional echocardiography we calculated the left ventricular mass and the correspondent index corrected for the body surface.


RESULTS
In the H group an comparing to the N group, the mean value of the daily systolic blood pressure was 112 +/- 6 mmHg and 159 +/- 8 mmHg (p < 0.001) respectively, diastolic blood pressure was 60 +/- 5 mmHg and 75 +/- 7 mmHg respectively (p < 0.001), heart rate blood pressure product was 6720 +/- 580 and 12561 +/- 678 (p < 0.0001) and of the left ventricular mass index was 109 +/- 10 gm2 and 145 +/- 7 g/m2 (p < 0.001). The correlation coefficient between the left ventricular mass index and mean systolic, diastolic blood pressures and ambulatory heart rate blood pressure product was 0.60 (p < 0.01), 0.45 (p = NS) and 0.73 (p < 0.001) respectively.


CONCLUSIONS
In the evaluation of the increase in left ventricular mass, ambulatory heart rate blood pressure product is a more accurate parameter compared to the mean daily blood pressure values. Ambulatory blood pressure monitoring is a method with a great potential and clinical application, when studying patients with hypertension diagnosis.
Azevedo
J
J
Laboratório de Ecocardiografia, Hospital Egas Moniz, Lisboa.
Arroja
I
I
Jacques
A
A
Santos
I
I
Amado
P
P
Marques
J C
JC
Araújo
V
V
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D015924:Blood Pressure Monitors / Q000706:statistics & numerical data; D002940:Circadian Rhythm; D004452:Echocardiography / Q000706:statistics & numerical data; D005260:Female; D006339:Heart Rate; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012044:Regression Analysis
Duplo produto ambulatório, hipertensão arterial ligeira e hipertrofia ventricular esquerda.