title: [Febrile status and micronodular changes of the lung parenchyma in HIV infection].
abstract: This 49-year-old man with the acquired immunodeficiency syndrome (AIDS) was admitted to the hospital because of fever, weight loss and respiratory symptoms. The radiograph of the chest showed diffuse fine nodular opacities. Histology of lung and lymph node revealed a necrotising granulomatosis and yeasts suggesting histoplasmosis. It's identity was confirmed by positive cultures for Histoplasma capsulatum in blood, urine, lung specimen and lymph node. There was a successful induction treatment and a maintenance therapy with amphotericin B. We discuss disseminated histoplasmosis in the immunodeficiency syndrome.
authors.affiliation: Medizinische Klinik, Stadtspital Triemli, Zürich.
authors.forename: R
authors.initials: R
authors.lastname: Wüthrich
authors.forename: G
authors.initials: G
authors.lastname: Hold
authors.forename: F
authors.initials: F
authors.lastname: Bannwart
authors.forename: E
authors.initials: E
authors.lastname: Imhof
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D000666:Amphotericin B / Q000627:therapeutic use; D001706:Biopsy; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011859:Radiography
chemical_list: D000666:Amphotericin B
vernacular_title: Status febrilis und feinnoduläre Lungenparenchymveränderung bei HIV-Infektion.