title: Adenosine deaminase activity in leprosy.
abstract: Serum adenosine deaminase (ADA) was studied in 60 patients of different types of leprosy and 50 healthy control subjects. ADA levels in patients with tuberculoid (50.50 +/- 5.22 U/L), borderline (41.14 +/- 3.89 U/L) and lepromatous leprosy (30.10 +/- .03 U/L) were higher than that in controls (17.84 +/- 2.78 U/L), thus correlating with the immunological status of patients. Patients with lepra reaction showed decreased ADA levels and higher grade of lepromin test positivity was associated with increased ADA activity.
authors.affiliation: Department of Medicine, Govt Medical College & Hospital, Aurangabad.
authors.forename: R K
authors.initials: RK
authors.lastname: Shende
authors.forename: J
authors.initials: J
authors.lastname: Bardapurker
authors.forename: V
authors.initials: V
authors.lastname: Patil
authors.forename: A
authors.initials: A
authors.lastname: Gaikwad
mesh_terms: D000243:Adenosine Deaminase / Q000097:blood / Q000378:metabolism*; D006801:Humans; D015439:Leprosy, Borderline / Q000201:enzymology*; D015440:Leprosy, Lepromatous / Q000201:enzymology*; D015441:Leprosy, Tuberculoid / Q000201:enzymology*
chemical_list: D000243:Adenosine Deaminase