[The prediction of the superactivity of embryo-toxic benzine and indole derivatives by the discriminant analysis method].
The discriminant functions allowing to predict the phenomenon of superactivity for some embryotoxic neurochemicals by means of tabular electronic and lipophilic parameters are received. The prognosis possibility of the received functions for benzene and indole derivatives on the sea urchin embryos is about 93%.
Ordukhanian
A A
AA
Buznikov
G A
GA
Landau
M A
MA
D000818:Animals; D001555:Benzene Derivatives / Q000737:chemistry / Q000633:toxicity*; D016002:Discriminant Analysis; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D007211:Indoles / Q000737:chemistry / Q000633:toxicity*; D011379:Prognosis; D012617:Sea Urchins; D013329:Structure-Activity Relationship
D001555:Benzene Derivatives; D007211:Indoles
Prognozirovanie fenomena sverkhaktivnosti émbriotoksicheskikh proizvodnykh benzola i indola s pomoshch'iu metoda diskriminantnogo analiza.