title: In-vitro susceptibility to antimicrobial drugs of bacterial isolates from horses in The Netherlands.
abstract: Minimum inhibitory concentrations (MICs) of 30 antimicrobial agents (including the hitherto unreported antimicrobial agents doxycycline, minocycline, vanomycin, 3 quinolones and 3 combinations of antimicrobial agents) for isolates of Salmonella spp. (20), Escherichia coli (17), Klebsiella spp. (8), Proteus spp. (7), Pseudomonas aeruginosa (7), Actinobacillus equuli (5), Rhodococcus equi (4), Streptococcus zooepidemicus (23), Streptococcus equisimilis (6), Streptococcus equi (4), coagulase-positive Staphylococcus spp. (20) and Taylorella equigenitalis (19) were determined using the agar dilution method. All isolates were of equine origin. MICs were compared with recommended MIC breakpoints. The results indicate that, for some of the pathogenic bacteria evaluated, susceptibility testing of isolates from the individual patient is essential to determine an appropriate antimicrobial treatment.
authors.affiliation: Department of General and Large Animal Surgery, Utrecht University, The Netherlands.
authors.forename: J M
authors.initials: JM
authors.lastname: Ensink
authors.forename: B
authors.initials: B
authors.lastname: van Klingeren
authors.forename: D J
authors.initials: DJ
authors.lastname: Houwers
authors.forename: W R
authors.initials: WR
authors.lastname: Klein
authors.forename: A G
authors.initials: AG
authors.lastname: Vulto
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D006736:Horses / Q000382:microbiology*; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D009426:Netherlands; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents