title: Verucopeptin, a new antitumor antibiotic active against B16 melanoma. II. Structure determination.
abstract: The structure of a new antibiotic verucopeptin has been determined by the spectroscopic analyses and chemical degradation studies. It is a 19-membered cyclodepsipeptide which is structurally related to azinothricin and A83586C.
authors.affiliation: Bristol-Myers Squibb Research Institute, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sugawara
authors.forename: S
authors.initials: S
authors.lastname: Toda
authors.forename: T
authors.initials: T
authors.lastname: Moriyama
authors.forename: M
authors.initials: M
authors.lastname: Konishi
authors.forename: T
authors.initials: T
authors.lastname: Oki
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry* / Q000494:pharmacology; D047630:Depsipeptides; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008546:Melanoma, Experimental / Q000188:drug therapy; D051379:Mice; D008969:Molecular Sequence Data; D010456:Peptides, Cyclic / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000903:Antibiotics, Antineoplastic; D047630:Depsipeptides; D010456:Peptides, Cyclic; C082424:verucopeptin