BU-4794F, a new beta-1,3-glucan synthase inhibitor.
New beta-1,3-glucan synthase inhibitor (BU-4794F) was isolated from the culture broth of Gilmaniella sp. FA4459. Structural studies indicated that it was a novel member of the papulacandin group of antibiotics.
Aoki
M
M
Bristol-Myers Squibb Research Institute, Tokyo, Japan.
Andoh
T
T
Ueki
T
T
Masuyoshi
S
S
Sugawara
K
K
Oki
T
T
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005658:Fungi / Q000737:chemistry*; D005964:Glucosyltransferases / Q000037:antagonists & inhibitors*; D008565:Membrane Proteins; D008826:Microbial Sensitivity Tests; D011714:Pyrans / Q000494:pharmacology; D029702:Schizosaccharomyces pombe Proteins; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D000935:Antifungal Agents; D001572:Benzofurans; D008565:Membrane Proteins; D011714:Pyrans; D029702:Schizosaccharomyces pombe Proteins; D013141:Spiro Compounds; C065110:L 687781; C082434:BU 4794F; D005964:Glucosyltransferases; C020570:1,3-beta-glucan synthase