Signal transduction by inflammatory cytokines.
The mechanisms by which the inflammatory cytokines interleukin-1 and interleukin-6, and tumour necrosis factor alpha activate cellular genes are reviewed. Common usage of some receptors and transcription factors are beginning to emerge, and many offer insights into newer therapeutic options.
Woo
P
P
Section of Molecular Rheumatology, Clinical Research Centre, Harrow, UK.
D001483:Base Sequence; D016207:Cytokines / Q000235:genetics / Q000502:physiology*; D005786:Gene Expression Regulation; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D007375:Interleukin-1 / Q000502:physiology; D015850:Interleukin-6 / Q000235:genetics / Q000502:physiology; D008969:Molecular Sequence Data; D015398:Signal Transduction
D016207:Cytokines; D007375:Interleukin-1; D015850:Interleukin-6