title: Psychosocial factors and recurrent genital herpes: a review of prediction and psychiatric treatment studies.
abstract: OBJECTIVE
  The purpose of this review was to evaluate the evidence which supports the association between psychosocial factors and genital herpes simplex virus recurrences (HSV), as well as to examine the biological and psychological treatments for disease.
  
  
  METHODS
  Forty-five studies were reviewed from the years 1928 to 1991. Studies were identified via computerized biographic literature search of Psychological Abstracts and Medline. Additional studies were located by inspection of key article reference sections. Studies were included in the review if the sample consisted of recurrent genital herpes sufferers and the design was either correlational or experimental. Cases studies were reviewed if they described HSV psychiatric treatment and provided outcome information.
  
  
  RESULTS
  Psychosocial variables are important elements in the prediction, maintenance, and management of recurrent genital herpes. Furthermore, the effectiveness of psychological treatment regimes may be explained via psychoimmunological theory.
  
  
  CONCLUSIONS
  Psychosocial treatment should be considered as adjunctive therapy for biological treatment of recurrent HSV infections. Future research should address primary prevention of genital herpes and other sexually transmitted diseases, including HIV infections.
authors.affiliation: Geisinger Medical Center, Danville, Pennsylvania.
authors.forename: D
authors.initials: D
authors.lastname: Longo
authors.forename: K
authors.initials: K
authors.lastname: Koehn
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000223:Adaptation, Psychological; D006558:Herpes Genitalis / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D008016:Life Change Events; D011336:Probability; D011602:Psychophysiologic Disorders / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011613:Psychotherapy; D012008:Recurrence; D012309:Risk-Taking; D013315:Stress, Psychological / Q000150:complications / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D000212:Acyclovir