title: [Cyclophosphamide bolus therapy in lupus nephritis--status of the clinical study].
abstract: In order to establish a low-dose cumulative cyclophosphamide therapy for lupus nephritis, 21 patients were either randomized for at least 3 i.v. cyclophosphamide pulses until remission occurred or for 12 pulses. 18/21 patients developed a remission after an average of 7.3 pulses and a cumulative cyclophosphamide dose of 9.3 g. Side effects were only mild.
authors.affiliation: Abteilung für Immunologie und Transfusionsmedizin, Medizinische Hochschule Hannover.
authors.forename: T
authors.initials: T
authors.lastname: Witte
authors.forename: D
authors.initials: D
authors.lastname: Schaumann
authors.forename: R
authors.initials: R
authors.lastname: Hein
authors.forename: K H
authors.initials: KH
authors.lastname: Neumann
authors.forename: K M
authors.initials: KM
authors.lastname: Koch
authors.forename: H
authors.initials: H
authors.lastname: Deicher
authors.forename: R E
authors.initials: RE
authors.lastname: Schmidt
mesh_terms: D003520:Cyclophosphamide / Q000008:administration & dosage*; D006801:Humans; D008181:Lupus Nephritis / Q000188:drug therapy*
chemical_list: D003520:Cyclophosphamide
vernacular_title: Cyclophosphamidbolus-Therapie bei Lupusnephritis--Stand der Therapiestudie.