Kin recognition. A model for the retention of Golgi enzymes.
The surprising result that the spanning domain causes retention of proteins in the Golgi stack poses the question as to the actual mechanism. Here we present a simple model that might have general applicability.
Nilsson
T
T
Imperial Cancer Research Fund, London, UK.
Slusarewicz
P
P
Hoe
M H
MH
Warren
G
G
D000595:Amino Acid Sequence; D001692:Biological Transport; D006056:Golgi Apparatus / Q000201:enzymology*; D008361:Mannosidases / Q000378:metabolism; D008954:Models, Biological; D008969:Molecular Sequence Data; D017351:N-Acetylglucosaminyltransferases / Q000378:metabolism; D009237:N-Acetyllactosamine Synthase / Q000378:metabolism; D011506:Proteins / Q000378:metabolism
D011506:Proteins; D017351:N-Acetylglucosaminyltransferases; C024850:alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase I; D009237:N-Acetyllactosamine Synthase; D008361:Mannosidases; C038829:mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidase