Neonatal lupus erythematosus and maternal lupus erythematosus mimicking HELLP syndrome.
A 4-month-old boy had a faint, confluent, macular erythema involving the forehead, nose, and philtrum, and matlike telangiectases over the forehead and eyelids. The clinical features, course, and laboratory studies were characteristic of neonatal lupus erythematosus. He was otherwise healthy and the product of a preterm twin pregnancy complicated by the development of maternal HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome. The patient had elevated Ro(SSA) and La(SSB) antibody titers, and studies performed on maternal blood disclosed positive antinuclear antibodies and elevated Ro and La antibody titers.
Paton
S
S
Dermatology Program, Children's Hospital, Boston, Massachusetts.
Wiss
K
K
Lyon
N
N
Baden
L
L
Gellis
S E
SE
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D017359:HELLP Syndrome / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007223:Infant; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000276:immunology
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies; C035357:SS-B antibodies