Percutaneous nephrostomy drainage in the treatment of severe hemorrhagic cystitis.
We report on 2 patients who underwent urinary diversion with bilateral percutaneous nephrostomy tube drainage for intractable hemorrhagic cystitis. Both patients received cyclophosphamide-based chemotherapy and 1 also underwent pelvic irradiation for locally advanced prostate adenocarcinoma. In each case the bleeding gradually ceased during a 1-week period. Both patients were alive at 6 months and were voiding spontaneously. We propose that the mechanism of treatment involves diverting endogenous urokinase as well as avoiding overdistention of the bladder.
Sneiders
A
A
Department of Urologic Surgery, University of Minnesota Hospital and Clinic, Minneapolis.
Pryor
J L
JL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003556:Cystitis / Q000150:complications / Q000601:surgery*; D004322:Drainage; D006470:Hemorrhage / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D009403:Nephrostomy, Percutaneous; D001745:Urinary Bladder Diseases / Q000209:etiology / Q000601:surgery*; D014547:Urinary Diversion