Bacteriology and drug susceptibility of tuberculosis at St Vincent's Hospital, Melbourne 1962-1991.
39,000 specimens were examined for the growth of Mycobacterium tuberculosis over a 27-year period (1962-1989) at St Vincent's Hospital, Melbourne. The culture positive rate was 2.0% overall but was as high as 3.5% for tissue specimens and less than 1% for specimens of pleural fluid. There were 329 culture positive patients over a 29-year period (1962-1991) of whom 34 (10.5%) yielded an isolate resistant to at least one anti-tuberculosis drug and 19 (5.8%) were resistant to isoniazid. An overall increase in the rate of drug resistance together with important ethnic group differences were noted.
Hurley
J C
JC
Microbiology Department, St. Vincent's Hospital, Melbourne, Australia.
Andrew
J H
JH
D004352:Drug Resistance, Microbial; D005006:Ethnicity; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification; D010996:Pleural Effusion / Q000382:microbiology; D013183:Sputum / Q000382:microbiology; D013270:Stomach / Q000382:microbiology; D014376:Tuberculosis / Q000208:ethnology / Q000382:microbiology*; D014556:Urine / Q000382:microbiology; D014739:Victoria