title: Depression in old age. A reconsideration of cerebral disease in relation to outcome.
abstract: In a prospective study, 32 patients with depressed mood and cerebral pathology were compared over one year with 66 depressed patients who were cerebrally intact. The hypothesis that the former would have a poorer outcome for depression was not confirmed, although the group with cerebral pathology had a significantly higher than expected death rate. Prognostic factors were identified only for the cerebrally intact group. Those who had major depression were more likely than those with minor depression to be given physical treatments, irrespective of which group they belonged to.
authors.affiliation: Manchester Royal Infirmary.
authors.forename: R C
authors.initials: RC
authors.lastname: Baldwin
authors.forename: S M
authors.initials: SM
authors.lastname: Benbow
authors.forename: A
authors.initials: A
authors.lastname: Marriott
authors.forename: B
authors.initials: B
authors.lastname: Tomenson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D000928:Antidepressive Agents / Q000627:therapeutic use; D001925:Brain Damage, Chronic / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D003430:Cross-Sectional Studies; D003704:Dementia / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D015161:Dementia, Multi-Infarct / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008016:Life Change Events; D008137:Longitudinal Studies; D008297:Male; D009483:Neuropsychological Tests; D010552:Personality Assessment; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents