title: [Early empiric antibiotic therapy of infectious complications in patients with neutropenia].
abstract: Aggressive chemotherapy used at present for the treatment of malignant haematological diseases leads to prolonged aplasia of the bone marrow with the possible development of fulminant infectious complications. Treatment of these complications must be started immediately when they are detected, i.e. as a rule without knowing the bacteriological finding at the time. The objective of the present work was to assess by analysis of 376 positive bacteriological findings from hospitalized patients with neutropenia and 141 findings of immunocompromised patients in their homes a combination of antibiotics for empirical treatment of infectious complications which developed during hospitalization or treatment at home.
authors.affiliation: II. interní klinika FNsP Brno Bohunice.
authors.forename: H
authors.initials: H
authors.lastname: Kubesová
authors.forename: J
authors.initials: J
authors.lastname: Zemanová
authors.forename: J
authors.initials: J
authors.lastname: Vorlícek
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects; D001424:Bacterial Infections / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced / Q000150:complications*; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents
vernacular_title: Casná empirická antibiotická lécba infekcních komplikací u nemocných s neutropenií.