Immunoreactive endothelins in human follicular fluid.
Endothelin levels were measured by means of [125I]endothelin-1,2,3 radioimmunoassay in the follicular fluids of 22 mature ovarian follicles of 11 patients, obtained during ovum pickup. In all but 1 of the follicles, endothelin levels were detectable and ranged between 0.2 and 3.6 pg/ml (mean 1.47 +/- 0.99). In this preliminary study, no correlation was found between follicular endothelin levels and oocyte fertilization or the hormonal ovarian response during the follicular phase.
Schiff
E
E
Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Aviv University, Israel.
Alcalay
M
M
Peleg
E
E
Rosenthal
T
T
Mashiach
S
S
Dor
J
J
D016232:Endothelins / Q000032:analysis*; D005260:Female; D005307:Fertilization in Vitro; D015571:Follicular Fluid / Q000737:chemistry*; D006801:Humans; D008297:Male; D006080:Ovarian Follicle / Q000502:physiology; D010062:Ovulation Induction; D011863:Radioimmunoassay
D016232:Endothelins