title: Intraoperative procurement of autologous fibrin glue.
abstract: A method of intraoperative procurement of autologous fibrin glue is described. The relative efficacy of our autologous preparation is compared with that of fibrin glue made with homologous cryoprecipitate. Experimentally, the fibrinogen content and the strength are less than those found in cryoprecipitate and appear related to the fibrinogen content of the autologous plasma used as substrate in the fibrin glue reaction. Clinically, no significant differences are noted in the performance of autologous fibrin glue. We believe the absence of the risk of blood-borne infection with the autologous product is a major advantage.
authors.affiliation: Department of Surgery, Northwestern University, Evanston Hospital, Illinois 60201.
authors.forename: R L
authors.initials: RL
authors.lastname: Quigley
authors.forename: J A
authors.initials: JA
authors.lastname: Perkins
authors.forename: R J
authors.initials: RJ
authors.lastname: Gottner
authors.forename: R D
authors.initials: RD
authors.lastname: Curran
authors.forename: B E
authors.initials: BE
authors.lastname: Kuehn
authors.forename: W J
authors.initials: WJ
authors.lastname: Hoff
authors.forename: M E
authors.initials: ME
authors.lastname: Wallock
authors.forename: C E
authors.initials: CE
authors.lastname: Arentzen
authors.forename: J C
authors.initials: JC
authors.lastname: Alexander
mesh_terms: D000268:Adhesiveness; D000818:Animals; D015718:Fibrin Tissue Adhesive / Q000737:chemistry; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D007432:Intraoperative Period; D012867:Skin; D013514:Surgical Procedures, Operative
chemical_list: D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen