title: [Primary aspergillus endocarditis].
abstract: A 38-year old man was admitted for investigation of suspected endocarditis presenting with two cerebrovascular accidents and pyrexia. The initial clinical, echocardiographic and infectious investigations were normal, apart from a neutrophilic leukocytosis. The clinical course was marked by the recurrence of systemic embolism in the lower limbs, the appearance of cervical and axillary lymphadenopathy and, within a short period of time, of massive aortic valve vegetations. The diagnosis of aspergillosis was made from the culture of a peripheral embolus recovered by a Fogarty catheter and this was confirmed by the positivity of serological investigations. The patient died within two months despite antifungal therapy. Aspergillus endocarditis is characterised by its rapid progression, the volume and embolic tendency of the vegetations, the relative inefficacy of medical therapy and the potential benefits of early surgical management.
authors.affiliation: Service de soins intensifs et de réanimation cardiologiques, Hôpital cardiologique de Lille.
authors.forename: J C
authors.initials: JC
authors.lastname: Aisenfarb
authors.forename: M
authors.initials: M
authors.lastname: Dupré-Minet
authors.forename: P
authors.initials: P
authors.lastname: Asseman
authors.forename: E
authors.initials: E
authors.lastname: Chammas
authors.forename: M
authors.initials: M
authors.lastname: Lesenne
authors.forename: C
authors.initials: C
authors.lastname: Théry
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000150:complications* / Q000188:drug therapy; D002544:Cerebral Infarction / Q000209:etiology; D004696:Endocarditis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D014463:Ultrasonography
vernacular_title: Endocardite aspergillaire primitive.