Metabolic alterations in organs of Meriones unguiculatus infected with Echinococcus multilocularis.
1. 1H-NMR spectra of liver, spleen and kidney extracts from Meriones unguiculatus infected with Echinococcus multilocularis showed decreased levels of glucose. In addition, the liver extracts were severely glycogen-depleted. 2. Both livers and spleens contained less glycine, taurine and acetate. Spleens also had fewer cholines and less lactate but more betaine and alanine. 3. In the kidneys, elevated concentrations of succinate, acetate and lactate were found.
Novak
M
M
Department of Biology, University of Winnipeg, Manitoba, Canada.
Modha
A
A
Blackburn
B J
BJ
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001622:Betaine / Q000378:metabolism; D002264:Carboxylic Acids / Q000378:metabolism; D002794:Choline / Q000378:metabolism; D004443:Echinococcosis / Q000378:metabolism*; D005849:Gerbillinae; D005947:Glucose / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D013154:Spleen / Q000378:metabolism*; D013654:Taurine / Q000378:metabolism
D000596:Amino Acids; D002264:Carboxylic Acids; D013654:Taurine; D001622:Betaine; D006003:Glycogen; D005947:Glucose; D002794:Choline