title: Kyrle's disease. Effectively treated with isotretinoin.
abstract: Kyrle's disease is an uncommon dermatologic entity with characteristic clinical and histopathologic features. A case is recorded in a 63-year-old man undergoing hemodialysis for chronic renal failure. Systemic isotretinoin treatment for 13 weeks resulted in a complete clearance of the cutaneous lesions. Systemic treatment is effective and could be considered preferred therapy.
authors.affiliation: University of Florida Health Science Center, Jacksonville.
authors.forename: H A
authors.initials: HA
authors.lastname: Saleh
authors.forename: K M
authors.initials: KM
authors.lastname: Lloyd
authors.forename: S
authors.initials: S
authors.lastname: Fatteh
mesh_terms: D004439:Eccrine Glands / Q000473:pathology; D006197:Hair / Q000473:pathology*; D006801:Humans; D015474:Isotretinoin / Q000627:therapeutic use*; D007642:Keratosis / Q000188:drug therapy* / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects
chemical_list: D015474:Isotretinoin