High-performance liquid chromatographic analysis of cyclosporine A in human skin.
A three-dimensional high-performance liquid chromatography (HPLC) method is described for the determination of cyclosporine A in human skin. The method allows to determine at least 3 ng cyclosporine A in 10 mg skin (total sample amount needed) and is suitable for cyclosporine A level monitoring in the skin of psoriatic patients.
Husek
A
A
Department of Medical Chemistry, Medical Faculty, Palacky University, Olomouc, Czech Republic.
Eibler
E
E
Wiegrebe
W
W
D002851:Chromatography, High Pressure Liquid; D016572:Cyclosporine / Q000032:analysis*; D006801:Humans; D012867:Skin / Q000737:chemistry*
D016572:Cyclosporine