title: Administration errors with a conventional metered dose inhaler versus a novel breath actuated device.
abstract: Metered dose inhalers are difficult for patients to use. A device that eliminates coordination and timing of actuation may simplify the use of metered dose inhalers. This trial compared (1) number of errors made and (2) specific errors made between the conventional press and breathe metered dose inhaler (MDI) and the novel breath actuated Autohaler inhalation device in 24 subjects. We studied the use of each device in 12 patients trained and experienced in using an MDI and in 12 volunteers who had never been exposed to any inhalation device. We observed that even experienced patients continue to have difficulty with the coordination and timing of metered dose inhalers. The volunteer group had equal difficulty with both devices but it appeared that it was easier for them to learn how to use the breath actuated device than the MDI.
authors.affiliation: College of Pharmacy, University of Minnesota, Minneapolis.
authors.forename: J S
authors.initials: JS
authors.lastname: Larsen
authors.forename: M
authors.initials: M
authors.lastname: Hahn
authors.forename: J W
authors.initials: JW
authors.lastname: Kochevar
authors.forename: R J
authors.initials: RJ
authors.lastname: Morris
authors.forename: H B
authors.initials: HB
authors.lastname: Kaiser
authors.forename: S C
authors.initials: SC
authors.lastname: Weisberg
authors.forename: P C
authors.initials: PC
authors.lastname: Halverson
authors.forename: S N
authors.initials: SN
authors.lastname: Quessy
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008508:Medication Errors; D008875:Middle Aged; D009330:Nebulizers and Vaporizers / Q000592:standards*; D012138:Respiratory Therapy / Q000379:methods