ABP50: an actin-binding elongation factor 1 alpha from Dictyostelium discoideum.
ABP50 is a polypeptide elongation factor 1 alpha from Dictyostelium that is associated with the actin cytoskeleton. Upon chemotactic stimulation, ABP50 undergoes a dramatic cytoplasmic redistribution into newly formed surface projections and in vitro binds to and bundles actin filaments. Many questions are raised by this interaction pertaining to the spatiotemporal regulation of protein synthesis and cytoskeletal organization by extracellular signals.
Edmonds
B T
BT
Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461.
D000199:Actins / Q000378:metabolism*; D000595:Amino Acid Sequence; D000818:Animals; D004023:Dictyostelium / Q000378:metabolism*; D005656:Fungal Proteins / Q000378:metabolism*; D008969:Molecular Sequence Data; D010445:Peptide Elongation Factors / Q000378:metabolism*; D015800:Protozoan Proteins; D017386:Sequence Homology, Amino Acid
C073748:ABP-50 protein, Dictyostelium; D000199:Actins; D005656:Fungal Proteins; D010445:Peptide Elongation Factors; D015800:Protozoan Proteins