[Treatment of endometrial hyperplasia with Goserelin depot, an LH-RH analog].
Nineteen patients with simple endometrial hyperplasia presenting metrorrhagia or menometrorrhagia were treated with 4 injections of Goserelin depot, one every 4 weeks. 12/19 patients were refractory after previous medical therapy. The treatment with Goserelin depot resulted in a complete remission of the symptoms, occurring within the first month of treatment and still present after a median follow-up of 12 months, and in the normalization of the histological profile. No patient experienced clinically relevant side effects.
Pozzi
M
M
Divisione di Ginecologia Oncologica, Istituto Regina Elena per lo Studio e la Cura dei Tumori, Roma.
Castagnola
D
D
Cherubini
F
F
D001706:Biopsy; D003692:Delayed-Action Preparations; D004714:Endometrial Hyperplasia / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D004717:Endometrium / Q000473:pathology; D005260:Female; D017273:Goserelin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008595:Menorrhagia / Q000209:etiology; D008796:Metrorrhagia / Q000209:etiology
D003692:Delayed-Action Preparations; D017273:Goserelin
Trattamento dell'iperplasia dell'endometrio con Goserelin depot, un analogo dell'LH-RH.