title: Crystals of a hammerhead ribozyme.
abstract: Hammerhead ribozyme-inhibitor complexes consisting of an RNA "enzyme" strand and a DNA "inhibitor" strand have been crystallized in four different crystal forms. The crystal form that is most attractive for structure determination diffracts to approximately 3.2 A resolution; it is trigonal, space group P3(1)21 or enantiomorph, a = 92.5 A, c = 185.0 A.
authors.affiliation: Beckman Laboratories for Structural Biology, Department of Cell Biology, Stanford University School of Medicine, California 94305.
authors.forename: H W
authors.initials: HW
authors.lastname: Pley
authors.forename: D S
authors.initials: DS
authors.lastname: Lindes
authors.forename: C
authors.initials: C
authors.lastname: DeLuca-Flaherty
authors.forename: D B
authors.initials: DB
authors.lastname: McKay
mesh_terms: D001482:Base Composition; D001483:Base Sequence; D003460:Crystallization; D004247:DNA / Q000138:chemical synthesis / Q000737:chemistry; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis / Q000737:chemistry; D016337:RNA, Catalytic / Q000138:chemical synthesis / Q000737:chemistry* / Q000302:isolation & purification; D014961:X-Ray Diffraction / Q000379:methods
chemical_list: D009838:Oligodeoxyribonucleotides; D016337:RNA, Catalytic; D004247:DNA