An automated aerosol actuator: application to the uniformity testing of pharmaceutical aerosol dosage forms.
An automated system for valve performance testing to determine net weight loss per actuation of pharmaceutical aerosol dosage forms has been developed and is described. The principal element of the system is a novel automatic aerosol actuation device. Details of the validation, comparison to manual methods of analysis and advantages are presented. The automated system has been shown to be a cost-effective, productive and facile alternative to manual testing.
Mazzo
D J
DJ
Department of Analytical and Physical Chemistry, Rhône-Poulenc Rorer Central Research, Collegeville, PA 19426.
Engerer
R
R
Egoville
J
J
D000336:Aerosols / Q000008:administration & dosage / Q000032:analysis*; D001322:Autoanalysis; D008838:Microcomputers; D012371:Robotics; D012984:Software
D000336:Aerosols