title: NMR and time-resolved optical studies of brain imaging.
abstract: The classical optical method of the biochemist used in so many applications to determine stoichiometry kinetics, quantitative analysis of biochemical systems which was subsequently applied to tissue studies by G.A. Millikan and others seems now to have a new lease on life provided by time and frequency resolved studies which appear to afford the essential quantification lacking in the earlier methods. The fact that localization seems possible as well may bring the optical technology into the arena of new non-invasive technology capable of high sensitivity, high resolution and rapid data acquisition.
authors.affiliation: University of Pennsylvania, Department of Biochemistry and Biophysics Johnson Foundation, Philadelphia.
authors.forename: B
authors.initials: B
authors.lastname: Chance
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D003071:Cognition; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010100:Oxygen / Q000378:metabolism; D010759:Phosphorus Isotopes; D013996:Time and Motion Studies
chemical_list: D010759:Phosphorus Isotopes; D010100:Oxygen