[Features of the distribution of alleles of the HLA-DRB1 04 and HLA-DQB1 03 genes among healthy people of European origin in Western Siberia].
The allelic HLA-DRB1 04 and HLA-DQB1 03 polymorphism in caucasians living among the West Siberia Mongoloid aborigenes was studied. As a result of our studies, it was shown that the HLA-DRB1 0403/07 predominates and HLA-DRB1 0404/08 is absent in the Russian population of West Siberia, in contrast to those among Caucasians living in West Europe and North America. The frequencies of HLA-DQB1 03 alleles are similar to those observed among the all Caucasians. Gametic association HLA-DR4 - HLA-DQw was found for the first time in Caucasians of West Siberia.
Sartakova
M L
ML
Medical Institute of Bioregulation, Fucuoka, Japan.
Konenkov
V I
VI
Kimura
A
A
D000328:Adult; D000483:Alleles; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D005060:Europe / Q000208:ethnology; D005260:Female; D005787:Gene Frequency; D006683:HLA-DQ Antigens / Q000235:genetics*; D006684:HLA-DR Antigens / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D012016:Reference Values; D012800:Siberia; D044465:White People / Q000235:genetics*
D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens
Osobennosti raspredeleniia alleleĭ genov HLA-DRB1 04 i HLA-DQB1 03 sredi zdorovykh lits Evropeĭskogo proiskhozhdeniia v Zapadnoĭ Sibiri.