Biochemical polymorphisms in Long-Evans Cinnamon (LEC) inbred strain of rat.
Long-Evans Cinnamon (LEC) rat is an inbred strain of mutant rat which has been proposed to be an animal model for human Wilson's disease. In the present study, 28 genetic marker proteins were analyzed by electrophoresis in sublines of LEC inbred strain held separately by four facilities. As expected, the 27 markers were homozygous and identical in all of examined animals. We further found a novel variant of esterase-2 (ES-2) showing an intermediate mobility between profiles of ES-2A and ES-2C types.
Yamada
T
T
Institute for Animal Experimentation, University of Tokushima School of Medicine, Japan.
Moralejo
D
D
Agui
T
T
Matsumoto
K
K
D000818:Animals; D004195:Disease Models, Animal; D004798:Enzymes / Q000235:genetics; D005819:Genetic Markers; D014644:Genetic Variation; D006527:Hepatolenticular Degeneration / Q000235:genetics; D006720:Homozygote; D006801:Humans; D010375:Pedigree; D011110:Polymorphism, Genetic; D051381:Rats; D011922:Rats, Mutant Strains / Q000235:genetics*
D004798:Enzymes; D005819:Genetic Markers