title: Isolation and identification of a novel peptide from the accessory sex gland of the female house fly, Musca domestica.
abstract: A peptide of novel structure was isolated from accessory glands of the female house fly, Musca domestica by molecular-weight limit centrifugal ultrafiltration and reversed-phase HPLC. After amino acid and protein sequence analyses, the structure of this peptide was confirmed by chemical synthesis and plasma desorption mass spectral analysis to be Leu-Leu-Asn-Ala-Leu-Pro-Leu-Asp-Ala-Leu-Ser-Ser-Leu-Thr-Gly-NH2. The accessory gland peptide stimulated contraction of the house fly oviduct at concentrations of 10(-7) M and above.
authors.affiliation: United States Department of Agriculture, Livestock Insects Laboratory, Livestock, Beltsville, MD.
authors.forename: R M
authors.initials: RM
authors.lastname: Wagner
authors.forename: C W
authors.initials: CW
authors.lastname: Woods
authors.forename: J A
authors.initials: JA
authors.lastname: Hayes
authors.forename: J P
authors.initials: JP
authors.lastname: Kochansky
authors.forename: J C
authors.initials: JC
authors.lastname: Hill
authors.forename: B A
authors.initials: BA
authors.lastname: Fraser
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D005260:Female; D005836:Genitalia, Female / Q000737:chemistry*; D006793:Houseflies / Q000502:physiology*; D007301:Insect Hormones / Q000302:isolation & purification* / Q000494:pharmacology*; D008969:Molecular Sequence Data; D010057:Oviducts / Q000187:drug effects*; D017421:Sequence Analysis
chemical_list: D000596:Amino Acids; D007301:Insect Hormones; C082629:accessory sex gland peptide, Musca domestica