Recovery of fertility 14 years following radiotherapy and chemotherapy for testicular tumour.
We report a patient who developed a left-sided malignant teratoma with ipsilateral para-aortic nodes at the age of 20 years. Following treatment with left orchidectomy, abdominal and pelvic radiotherapy and chemotherapy, he was found to be azoospermic. More than 14 years after treatment, he regained his fertility. Similar prolonged iatrogenic depression of spermatogenesis has been reported in younger lymphoma patients; however, in post-pubertal patients with testicular tumour this has not been frequently reported.
Chakraborti
P R
PR
Department of Radiotherapy and Oncology, Royal London Hospital, UK.
Neave
F
F
D000328:Adult; D003131:Combined Modality Therapy / Q000009:adverse effects; D005298:Fertility; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000209:etiology; D013724:Teratoma / Q000503:physiopathology / Q000628:therapy*; D013736:Testicular Neoplasms / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors