The control of oocyte maturation in the starfish and amphibians by serotonin and its antagonists.
Serotonin acts as antagonist of progesterone on amphibian oocytes. Serotonin antagonists inhibit maturation of starfish oocytes and stimulate or trigger maturation in amphibians. We propose that endogenous serotonin participates in the control of oocyte maturation.
N.K. Koltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow.
G A
GA
Buznikov
L A
LA
Nikitina
Galanov AYu
L A
LA
Malchenko
O B
OB
Trubnikova
D000225:Adenine / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D007700:Kinetics; D009865:Oocytes / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D011374:Progesterone / Q000494:pharmacology; D012621:Seasons; D012701:Serotonin / Q000494:pharmacology*; D012702:Serotonin Antagonists / Q000494:pharmacology*; D013215:Starfish; D014982:Xenopus laevis
D012702:Serotonin Antagonists; D012701:Serotonin; D011374:Progesterone; C008407:1-methyladenine; D000225:Adenine