[Measurement of collagen content in articular cartilage of normal Chinese].
We determine the collagen contents of fresh articular cartilage from 188 normal Chinese who died in accidents. Among them, the collagen content of femoral head cartilage (104 cases) was 496 +/- 35mg/g, femoral condyle cartilage (62) 456 +/- 38mg/g, and humeral head cartilage 588 +/- 42mg/g. The normal range of collagen contents in Chinese articular cartilage was defined for the pathological studies of collagen metabolic changes in cartilage. The collagen contents of the non-loading areas were evidently higher than those of the loading ones. The more pressure the cartilage beared, the less collagen contents it contained. In our experiment, the disturbances of "free" hydroxyproline were eliminated by analysing hydroxyproline with rehydrolysis after extraction with heated trichloroacetic acid.
Department of Orthopaedic Surgery, 3rd Teaching Hospital, Norman Bethune University of Medical Sciences, Changchun.
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Zhu
D000293:Adolescent; D000328:Adult; D002358:Cartilage, Articular / Q000737:chemistry*; D003094:Collagen / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013053:Spectrophotometry; D016474:Weight-Bearing
D003094:Collagen