Pulmonary sporotrichosis treated with itraconazole.
A 62-year-old woman had chronic cavitary pulmonary sporotrichosis refractory to medical management over an 8-year period. She was treated with oral itraconazole and had an apparent microbiologic and clinical response; however, the patient succumbed to progressive pulmonary hypertension. The early use of oral itraconazole for treatment of pulmonary sporotrichosis is advocated.
Infectious Disease Division, Brigham and Women's Hospital, Boston.
J L
JL
Breeling
L
L
Weinstein
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008172:Lung Diseases, Fungal / Q000188:drug therapy*; D008875:Middle Aged; D011193:Potassium Iodide / Q000627:therapeutic use; D013174:Sporotrichosis / Q000188:drug therapy*
D000935:Antifungal Agents; D011193:Potassium Iodide; D017964:Itraconazole; D000666:Amphotericin B; D007654:Ketoconazole