[Thioredoxin-reductase: structure, properties, and function].
Thioredoxin reductase (TR-RED) pertains to the family of pyridine nucleotide disulfide oxidoreductases distinguished by their remarkable structural homology. The enzyme is a constituent component of the thioredoxin complex which is present in all types of organisms and is universal in respect of the numerous physiological functions it performs. The ability of TR-RED to protect the skin from UV-generated free oxygen species has been found. Owing to its ability to control melanin biosynthesis, the enzyme "doses" the suntan.
Labudova
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Kollarova
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D000595:Amino Acid Sequence; D002478:Cells, Cultured; D004926:Escherichia coli / Q000201:enzymology; D005609:Free Radicals; D006801:Humans; D015603:Keratinocytes / Q000201:enzymology / Q000378:metabolism; D008543:Melanins / Q000096:biosynthesis; D008969:Molecular Sequence Data; D013880:Thioredoxin-Disulfide Reductase / Q000737:chemistry* / Q000378:metabolism
D005609:Free Radicals; D008543:Melanins; D013880:Thioredoxin-Disulfide Reductase