Microbiological and clinical monitoring of non-localized juvenile periodontitis in young adults: a report of 11 cases.
It has been shown that patients with localized juvenile periodontitis (LJP) often harbor Actinobacillus actinomycetemcomitans in the subgingival area. However, little is known of the oral microflora in non-LJP juvenile periodontitis patients with less extensive disease. The purpose of this study was to describe the microflora and clinical parameters of young adults with minor to moderate periodontitis during treatment for a period of 1 year. Eleven patients 15 to 16 years of age were studied. All of them had 4 to 8 mm loss of attachment at minimally one site, but the typical clinical description of localized juvenile periodontitis was an exclusion criterion in this study. Microbiological examination of the deepest periodontal pocket and of the tongue revealed that 6 patients harbored Actinobacillus actinomycetemcomitans and 5 harbored Porphyromonas gingivalis. Almost all subjects showed relatively high proportions of Prevotella intermedia, Campylobacter rectus, motile organisms, and spirochetes. On the basis of clinical and microbiological parameters the 11 patients could be assigned to 1 of 2 groups. Six cases had moderate periodontal breakdown with loss of attachment at 7 to 44 sites. All harbored A. actinomycetemcomitans and 5 of them P. gingivalis. These 6 cases responded relatively well to initial treatment despite the continued presence of A. actinomycetemcomitans. The other group consisted of 5 cases with relatively minor periodontal breakdown; i.e, 1 or 2 sites with 4 to 6 mm loss of attachment. Neither A. actinomycetemcomitans nor P. gingivalis was detected in the deepest pocket of these patients. All 5 responded well to initial treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
Department of Oral Microbiology, Academic Centre for Dentistry Amsterdam, The Netherlands.
T J
TJ
van Steenbergen
U
U
van der Velden
F
F
Abbas
J
J
de Graaff
D000293:Adolescent; D016976:Aggregatibacter actinomycetemcomitans / Q000254:growth & development / Q000302:isolation & purification; D010520:Aggressive Periodontitis / Q000382:microbiology* / Q000628:therapy; D001439:Bacteroides / Q000254:growth & development / Q000302:isolation & purification; D002167:Campylobacter / Q000302:isolation & purification; D015169:Colony Count, Microbial; D012534:Dental Scaling; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D016745:Root Planing; D013144:Spirochaetales / Q000302:isolation & purification; D014059:Tongue / Q000382:microbiology