[Pre-therapeutic prognostic factors of survival in small cell bronchial cancer. Retrospective study in a series of 112 patients].
Pretherapeutic prognostic factors were studied retrospectively in 112 consecutive patients diagnosed as small cell lung cancer between January 1st 1986 and December 30th 1990 in our department. Mean age of the population was 59.3, 89.3% were males. Median survival time of the whole population is 11.66 months. It is 15.3 months for the 48 patients with limited disease stage and 9.74 months for 64 patients with extensive disease stage. Among the patients with limited disease stage, those with supraclavicular lymph nodes had a significantly shorter survival (p < 0.001). Univariate analysis of survival identified age, performances status, weight loss, T, N, bone and liver involvement, serum sodium, albumin and sedimentation rate as prognostic factors. The final model in multivariate analysis of survival includes for the patients with performance status < or = 70, extent of disease as an independent prognostic factor and for the patients with performance status < 70, extent of disease, serum sodium and albumin.
Pavillon Laënnec, Hôpitaux universitaires de Strasbourg.
E
E
Quoix
G
G
Hedelin
R
R
Seibert
E
E
Popin
A
A
Dietemann
N
N
Roeslin
G
G
Pauli
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001799:Blood Sedimentation; D018288:Carcinoma, Small Cell / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology; D005260:Female; D005602:France / Q000453:epidemiology; D006785:Hospitals, University; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D008940:Mitotic Index; D009367:Neoplasm Staging; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D012709:Serum Albumin / Q000032:analysis; D012964:Sodium / Q000097:blood; D016019:Survival Analysis; D015996:Survival Rate; D015431:Weight Loss
D012709:Serum Albumin; D012964:Sodium