A sensitive high-performance liquid chromatographic determination of 6-(pyridin-3-yl)-quinolin-2(1H)-one and its N-oxide metabolite in rat plasma and urine.
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Department of Bioanalytical Sciences, Wellcome Research Laboratories, Beckenham, UK.
Damani
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Rance
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D000818:Animals; D002316:Cardiotonic Agents / Q000032:analysis* / Q000097:blood / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D003497:Cyclic N-Oxides / Q000032:analysis / Q000097:blood; D004285:Dogs; D007202:Indicators and Reagents; D011725:Pyridines / Q000032:analysis* / Q000097:blood / Q000652:urine; D015363:Quinolones / Q000032:analysis* / Q000097:blood / Q000652:urine; D051381:Rats; D012015:Reference Standards; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
D002316:Cardiotonic Agents; D003497:Cyclic N-Oxides; D007202:Indicators and Reagents; D011725:Pyridines; D015363:Quinolones; C075393:6-(pyridin-3-yl)quinolin-2(1H)-one; C082956:UK 59572