Hematocrit influence on peritoneal dialysis effectiveness during recombinant human erythropoietin treatment in patients with chronic renal failure.
Seven intermittent peritoneal dialysis (IPD) patients were investigated before and after correction of anemia with recombinant human erythropoietin (r-HuEPO). When hematocrit exceeded 30%, the peritoneal equilibration test was performed at 1, 2, 4, 8 hours. Correction of anemia was associated with a mean value increment in creatinine and phosphate clearance in 1- and 2-hour dwells. Differences in clearance of sodium, potassium, and urea in protein loss and glucose absorption before and after r-HuEPO therapy were not statistically significant. Increased creatinine and phosphate clearance during short dwells can be effected in IPD patients.
Ksiazek
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Nephrology Department, Medical Academy of Lublin, Poland.
Baranowska-Daca
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D000328:Adult; D000740:Anemia / Q000097:blood / Q000209:etiology / Q000628:therapy; D003404:Creatinine / Q000378:metabolism; D004921:Erythropoietin / Q000627:therapeutic use*; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D010710:Phosphates / Q000378:metabolism; D011994:Recombinant Proteins / Q000627:therapeutic use
D006454:Hemoglobins; D010710:Phosphates; D011994:Recombinant Proteins; D004921:Erythropoietin; D003404:Creatinine