[Evaluation of gonadal hormone function in adolescent girls after antineoplastic therapy].
In 17 girls after the complex anti-neoplasm therapy we estimated the state of genital organs and the course of menorrhagia cycle together with plasma levels of beta-estradiol, progesterone and prolactin assessed by RIA. We found the secondary lack of menorrhagia together with lowered progesterone and beta-estradiol levels in 3 girls, in whom the abdominal cavity was irradiated. In other 3 girls the transient lack of menorrhagia was stated in the course of chemotherapy.
Wszelaki-Lass
E
E
Instytutu Połoznictwa i Chorób Kobiecych Akademii Medycznej, Gdańsku.
Korzon
M
M
Bohdan
Z
Z
Kuźmińska
A
A
D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008598:Menstruation / Q000097:blood / Q000187:drug effects* / Q000528:radiation effects*; D009369:Neoplasms / Q000628:therapy; D011374:Progesterone / Q000097:blood*; D011388:Prolactin / Q000097:blood; D011863:Radioimmunoassay; D011878:Radiotherapy / Q000009:adverse effects*
D000970:Antineoplastic Agents; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin