Life-threatening right ventricular thrombosis in association with phospholipid antibodies.
An 18 year old man presented with cough and dyspnoea caused by pulmonary infarction. A large friable mass of organising thrombus in an anatomically normal right ventricle was identified as an embolic source. The acute illness was associated with raised titres of anticardiolipin antibodies, one of the antiphospholipid group. This thrombus recurred after surgical removal but subsequently was dissipated after treatment with oral corticosteroids and long-term oral anticoagulation.
Department of Cardiology, East Birmingham Hospital.
S
S
O'Hickey
C
C
Skinner
J
J
Beattie
D000293:Adolescent; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications*; D003328:Coronary Thrombosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D011655:Pulmonary Embolism / Q000276:immunology / Q000628:therapy
D017152:Antibodies, Antiphospholipid; D000925:Anticoagulants