[Intermittent intra-arterial infusion chemotherapy of 5-FU and carboplatin for unresectable liver metastases].
Intermittent intra-arterial infusion chemotherapy (5-FU: 500 mg and carboplatin; 100 mg per week) using an implantable access was performed for 19 patients with unresectable liver metastasis of colon cancer (17 cases) and gastric cancer (2 cases). Survival time ranged from 12 to 641 days, and the average was 281.4 days with 50% survival at 276 days. Of 19 cases, one access was infected, two cases had catheter obstruction, and two cases had nausea and vomiting.
Koyama
H
H
First Dept. of Surgery, Kyoto Prefectural University of Medicine.
Taniguchi
H
H
Masuyama
M
M
Koishi
Y
Y
Tanaka
H
H
Miyata
K
K
Takeuchi
K
K
Oguro
A
A
Takahashi
T
T
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D016190:Carboplatin / Q000008:administration & dosage; D003110:Colonic Neoplasms / Q000473:pathology; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology
D016190:Carboplatin; D005472:Fluorouracil