Measurement of information processing delays in human visual cortex with repetitive magnetic coil stimulation.
Previous work disclosed that single magnetic coil (MC) pulses applied over human calcarine cortex could suppress perception of letters briefly presented, e.g. 80-100 ms earlier. Although individual MC stimuli presented 0-60 ms, or more than 140 ms after the visual stimulus were apparently ineffective, combinations of 2 or 3 MC pulses at such intervals temporarily depressed visual perception. Thus, progressing of such language information could be slowed, without being abolished. By contrast, when the first MC pulse was delivered 120 ms or later, a second MC pulse 40 ms later had no detectable effect, implying that calcarine cortex had already transmitted the information. Perceptual recovery of 5-character words initially occurred no earlier than that of random letters, nor or random letters vs. arbitrary linear patterns, implying that the processing delays in calcarine cortex were similar.
Amassian
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VE
Department of Physiology, State University of New York Health Science Center, Brooklyn 11203.
Maccabee
P J
PJ
Cracco
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RQ
Cracco
J B
JB
Rudell
A P
AP
Eberle
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L
D006801:Humans; D008280:Magnetics; D008606:Mental Processes / Q000502:physiology*; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology