[Infectious sinusitis in HIV infection. Clinical and therapeutic data on 20 patients].
To assess the clinical presentation and outcome of infectious sinusitis in HIV-infected patients, we analyzed in a retrospective study, the records of HIV-infected patients hospitalized from June 1986 to November 1989. Twenty-eight episodes of infectious sinusitis, defined by radiological signs, were recorded in 20 HIV-infected patients. Clinical presentation suggestive of acute sinusitis was inconstant and in 6 episodes a persistent fever was the only symptom. Concomitant pneumonia was detected in 8 episodes. Bacteria were isolated in 8 episodes, and in 4 of them, Haemophilus influenzae was identified. Clinical relapses occurred in 8/20 patients, requiring a surgical drainage in 3 cases. The frequency of relapses and the possibility of chronicity justify a more prolonged and aggressive therapy in infectious sinusitis occurring in HIV-infected patients.
Service des Maladies infectieuses et tropicales, Hôpital Bichat-Claude Bernard, Paris.
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F
Lacassin
P
P
Longuet
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C
Perronne
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C
Leport
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Gehanno
J L
JL
Vildé
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015521:Ethmoid Sinusitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D024841:Fluoroquinolones; D015522:Frontal Sinusitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D018942:Macrolides; D008297:Male; D015523:Maxillary Sinusitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012852:Sinusitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D015524:Sphenoid Sinusitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002969:Clavulanic Acids; D024841:Fluoroquinolones; D018942:Macrolides; D019818:Clavulanic Acid; D000658:Amoxicillin