Breast cancer developing after therapy for Hodgkin's disease.
Two patients developed breast cancer 14 and 8 years after treatment of Hodgkin's disease. Both had received mediastinal irradiation and MOPP chemotherapy. Because of the increased risk of breast cancer in women treated for Hodgkin's disease, as reported in the literature, we suggest the early initiation of periodic screening for breast cancer, to detect possible neoplasms at a more treatable stage.
Servizio di Oncologia, Ospedali Riuniti, Pesaro, Italy.
S
S
Cascinu
A
A
Fedeli
G
G
Catalano
D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000209:etiology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000209:etiology*; D003131:Combined Modality Therapy; D005260:Female; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D008466:Mechlorethamine / Q000008:administration & dosage; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000209:etiology*; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D011879:Radiotherapy Dosage; D014750:Vincristine / Q000008:administration & dosage
D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D011241:Prednisone