Discriminant analysis of clinical tests in histologic diagnosis of renal disease.
We have used discriminant analysis of the results of clinical examination to study whether or not it is possible to presume the histological findings of the kidney within the limits of the screening tests (urinalysis and blood tests) presently conducted at the outpatient clinic. A retrospective analysis was made of the data for 42 children who were found in school urine tests to have urinary abnormalities. Two discriminant functional equations were made and the overall rates of correct discrimination were > or = 90%. Proteinuria, IgA and complement titer were selected. These results were considered useful in determining the indication for renal biopsy.
Department of Pediatrics, Shimane Medical University, Japan.
A
A
Masutani
M
M
Inoue
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C
Mori
D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003937:Diagnosis, Differential; D016002:Discriminant Analysis; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D005921:Glomerulonephritis / Q000097:blood / Q000453:epidemiology / Q000473:pathology / Q000652:urine; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008403:Mass Screening / Q000379:methods*; D009393:Nephritis / Q000097:blood / Q000453:epidemiology / Q000473:pathology* / Q000652:urine; D012189:Retrospective Studies; D012572:School Health Services; D012680:Sensitivity and Specificity
D003176:Complement C3; D003181:Complement C4; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D005340:Fibrinogen