[The clinical morphofunctional determinants of restabilization in the course of acute forms of ischemic heart disease: approaches to the procedure for managing patients with unstable stenocardia].
There has been no concept of the ways of stabilizing the status in patients with unstable angina and preventing further coronary heart disease progression. The application of stress tests suggests that consequent use of transesophageal cardiac pacing and bicycle exercise makes it possible to work out an appropriate regime of graded exercise, to objectivize the patients' status to noninvasively evaluate the coronary reserve, to indirectly define the number of diseased vessels and their topology, and to evaluate the efficiency of therapy. To supplement stress echocardiography to examination techniques is of interest in studying left ventricular performance and segmental contractility. Based on their own studies, by using long-term monitoring of the status in terms of clinical features, dynamics of coronary reserve and myocardial function, changes in the blood lipid spectrum, immune link, the morphofunctional properties of platelets, neurohumoral factors, the authors propose a classification of unstable angina. The detected clinical and morphofunctional determinants of restabilization allow one to optimize a long-term management of patients with unstable angina, to identify groups at various risk and to improve the patients lifestyle in adequate drug correction.
Bobrov
V A
VA
Tashchuk
V K
VK
D000208:Acute Disease; D000789:Angina, Unstable / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D017202:Myocardial Ischemia / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*