Comparative gross and histological effects of the CO2 laser, Nd-YAG laser, scalpel, Shaw scalpel and cutting cautery on skin in rats.
Surgical instruments capable of sealing blood vessels while incising skin were compared to standard scalpel incisions in rats and the resultant scars examined in the early stages of wound healing for both gross and histological appearances. Those instruments which provide for hemostasis appear to do so with a delay in the early phases of wound healing.
Middleton
W G
WG
Department of Otolaryngology, University of Toronto, Canada.
Tees
D A
DA
Ostrowski
M
M
D000818:Animals; D002921:Cicatrix / Q000473:pathology / Q000503:physiopathology; D062109:Dermatologic Surgical Procedures; D004564:Electrocoagulation / Q000295:instrumentation*; D006488:Hemostasis, Surgical; D053685:Laser Therapy / Q000295:instrumentation*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000473:pathology; D012879:Skin Physiological Phenomena; D013525:Surgical Instruments; D014945:Wound Healing