Spectrophotometric analysis of a pharmaceutical preparation by principal component regression.
The use of a principal component regression procedure for quantitative analytical control of pharmaceutical preparations was investigated. The procedure was applied to the simultaneous quantitation of the active compound and preservative of a syrup by resolving their respective UV spectra. The most suitable conditions for quantitation were established and the results were compared with those obtained by HPLC.
Blanco
M
M
Departament de Química, Universitat Autònoma de Barcelona, Spain.
Coello
J
J
González
F
F
Iturriaga
H
H
Maspoch
S
S
D001549:Benzamides / Q000032:analysis*; D002626:Chemistry, Pharmaceutical; D002851:Chromatography, High Pressure Liquid; D012996:Solutions; D013053:Spectrophotometry
D001549:Benzamides; D012996:Solutions; C045316:cinitapride