Screening of blood donors for antibody to human immunodeficiency virus type 1.
29,575 blood donors of whom about 20% were voluntary were screened for HIV 1. During the three years period 1988 to 1990 four different tests kits were used. Three were ELISA methods and one an agglutination method. Comparison of the monthly seropositivity for each year showed variations of 0.9 to 4.4% for the first year, 1.4 to 10% for the second year and 0.2 to 6.9% for the third year. The differences in the standard errors were found to be significant. These wide differences are suggested to be due to many factors including the use of different screening kits, many first time donors and inability to perform repeat tests on positive samples.
National Blood Transfusion Service, Korle Bu Ghana.
J K
JK
Acquaye
D015492:AIDS Serodiagnosis / Q000191:economics / Q000379:methods; D000372:Agglutination Tests; D015982:Bias; D001782:Blood Donors; D003362:Cost-Benefit Analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005869:Ghana / Q000453:epidemiology; D006679:HIV Seropositivity / Q000097:blood / Q000453:epidemiology*; D015528:HIV Seroprevalence; D015497:HIV-1; D006801:Humans; D008403:Mass Screening / Q000191:economics / Q000379:methods; D011933:Reagent Kits, Diagnostic; D012621:Seasons; D012680:Sensitivity and Specificity
D011933:Reagent Kits, Diagnostic