Oxygen-dependent reduction of a nitroxide free radical by electron paramagnetic resonance monitoring of circulating rat blood.
The effects of fraction of inspired oxygen (FiO2) on the reduction of a nitroxide free radical were studied by X-band electron paramagnetic resonance (EPR) monitoring of circulating rat blood. The decay half-life of the metabolism/elimination phase increased significantly by 24 +/- 8% during hyperoxia and decreased significantly by 16 +/- 4% during hypoxia.
Department of Sciences and Biomedical Technologies, University L'Aquila, Italy.
V
V
Quaresima
C L
CL
Ursini
G
G
Gualtieri
A
A
Sotgiu
M
M
Ferrari
D000818:Animals; D003497:Cyclic N-Oxides / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D000860:Hypoxia / Q000097:blood*; D009589:Nitrogen Oxides / Q000097:blood* / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000097:blood*; D051381:Rats; D013113:Spin Labels
D003497:Cyclic N-Oxides; D005609:Free Radicals; D009589:Nitrogen Oxides; D013113:Spin Labels; C012517:proxyl nitroxide; D010100:Oxygen