Hepatocellular carcinoma coexistent with adenomatous hyperplasia: report of a case.
We would like to draw attention to hepatic tumor-like lesions which frequently complicate the differential diagnosis of hepatocellular carcinoma (HCC), while considering their pathology and diagnosis by radiographic imaging. In particular, adenomatous hyperplasia is recognized as a precancerous lesion of HCC, and the relationship between adenomatous hyperplasia and the multicentric development of HCC is recognized. We observed a patient who demonstrated hyperplastic changes in both the liver cells and a well-differentiated HCC lesion adjacent to the adenomatous hyperplasia, suggesting a multicentric development of the HCC. The histopathological features of adenomatous hyperplasia are also described.
First Department of Surgery, Faculty of Medicine, Kagoshima University, Japan.
K
K
Kurita
A
A
Yoshida
G
G
Tanabe
K
K
Shirao
M
M
Hamanoue
T
T
Aikou
H
H
Shimazu
D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia / Q000150:complications / Q000473:pathology; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000150:complications / Q000473:pathology*