Study of photodynamic reactions of p-nitroacetophenone using ESR and optical techniques.
The photosensitizing properties of p-nitroacetophenone (PNAP), a well-known radiosensitizer, have been studied in near UV region. The mechanism of PNAP photosensitization has been investigated by testing the efficiency of singlet oxygen production using photooxidation of 2,2,6,6-tetramethylpiperidine (TEMP) and photodegradation of guanosine. In both the cases, the enhancement effect of deuterated solvents has been observed. Results of these experiments suggest the significant role of type II mechanisms in PNAP photosensitization.
Krishna
C M
CM
Solid State & Molecular Physics Division, Saha Institute of Nuclear Physics, Bidhan Nagar, Calcutta.
Roy
A K
AK
D000098:Acetophenones / Q000737:chemistry / Q000528:radiation effects*; D003497:Cyclic N-Oxides / Q000528:radiation effects; D004578:Electron Spin Resonance Spectroscopy; D006151:Guanosine / Q000528:radiation effects; D066298:In Vitro Techniques; D010100:Oxygen / Q000528:radiation effects; D010777:Photochemistry; D011838:Radiation-Sensitizing Agents / Q000737:chemistry / Q000528:radiation effects*; D026082:Singlet Oxygen; D013056:Spectrophotometry, Ultraviolet; D013113:Spin Labels
D000098:Acetophenones; D003497:Cyclic N-Oxides; D011838:Radiation-Sensitizing Agents; D013113:Spin Labels; C001972:4-nitroacetophenone; D006151:Guanosine; D026082:Singlet Oxygen; D010100:Oxygen; C003959:TEMPO