[2-Guanidino-4(3H)-quinazolinones with chemotherapeutic activities].
Partially introduction of the biguanide structure into heterocyclic systems leads to various substituted 2-guanidino-4(3H)-chinazolinones. The compounds exhibit significant antimycotic and gyrase-inhibiting activities.
Institut für Pharmazie, Johannes-Gutenberg-Universität Mainz.
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Kreutzberger
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Balbach
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011799:Quinazolines / Q000138:chemical synthesis*; D059005:Topoisomerase II Inhibitors
D000935:Antifungal Agents; D011799:Quinazolines; D059005:Topoisomerase II Inhibitors