[The action of blood plasma and cerebrospinal fluid on the functional properties of human hemoglobin].
The blood plasma increases the O2 affinity and acid-base capacity of haemoglobin. The coefficient lg p50/pH is 2-5 times higher than Bohr coefficient. The effect remains unchanged after boiling of plasma, increases after dilution of haemoglobin and decreases after boiling of plasma with ethanol. The cerebrospinal fluid also increases the O2-affinity of haemoglobin. Probable mechanisms of the phenomenon are discussed.
Irzhak
L I
LI
Loshchinskiĭ
Iu V
IuV
D000328:Adult; D001930:Brain Injuries / Q000097:blood; D002021:Buffers; D002555:Cerebrospinal Fluid / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006454:Hemoglobins / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D010100:Oxygen / Q000097:blood; D010949:Plasma / Q000502:physiology*
D002021:Buffers; D006454:Hemoglobins; D010100:Oxygen