Efficacy of zeolitic ore compounds on the toxicity of aflatoxin to growing broiler chickens.
Commercially available zeolitic ore compounds, when incorporated into the diets at 0.5%, were evaluated for their ability to reduce the deleterious effects of 3.5 mg aflatoxin/kg feed on growing broiler chickens from 1 day to 3 weeks of age. In a series of four experiments, the compounds used included the following: mordenite (particle size of -20 mesh; Zeomite); clinoptilolite (particle size of -20 mesh; Zeobrite); SC Zeolite (particle size of -20 mesh); and clinoptilolite (particle size of -35 mesh; Clino 1) or clinoptilolite (particle sizes of -20 plus +35 mesh; Clino 2). Results demonstrated that 0.5% Zeobrite, Clino 1, or Clino 2 added to aflatoxin-contaminated diets did not significantly (P < 0.05) diminish the toxicity of high concentrations of aflatoxin to growing broiler chicks. Zeomite mordenite ore reduced the toxicity of aflatoxin to growing chicks by 41%, as indicated by weight gains, liver weight, and serum biochemical measurements, which compares favorably with its in vitro binding capacity to aflatoxin. SC Zeolite reduced weight-gain toxicity of aflatoxin by approximately 29%.
Harvey
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Food Animal Protection Research Laboratory, U.S. Department of Agriculture, College Station, Texas 77845.
Kubena
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Elissalde
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MH
Phillips
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TD
D000327:Adsorption; D000348:Aflatoxins / Q000037:antagonists & inhibitors* / Q000633:toxicity; D000538:Aluminum Silicates / Q000494:pharmacology*; D000818:Animals; D002645:Chickens / Q000254:growth & development*; D008297:Male; D010316:Particle Size; D015430:Weight Gain / Q000187:drug effects; D017641:Zeolites
D000348:Aflatoxins; D000538:Aluminum Silicates; C048397:mordenite; D017641:Zeolites