[DNA as a prognostic factor in colorectal cancer. A retrospective analysis of 34 patients].
OBJECTIVE
We study the tumoral DNA as a prognostic factor in patients operated for colo-rectal cancer.


METHODS
Retrospective. We analyze by flow cytometry the DNA content of tumoral tissue: Ploidy, DNA Index, Proliferative Index, S Phase.


METHODS
34 operated patients, for colo-rectal cancer, with a minimum 3 years of follow-up.


RESULTS
Ploidy doesn't show any relation with other prognostic factors. Only Dukes C aneuploid patients had more positive nodes than diploid. Ploidy was not related to better evolution or survival. Neither DNA Index, Proliferative Index and S Phase were related to the evolution of the disease.


CONCLUSIONS
The DNA study by flow cytometry has no better prognostic value then other classical factors.
Servicio Cirugía General, Consorci Sanitari de Mataró, Hospital Sant Jaume i Sta. Magdalena.
A
A
Bianchi
C
C
Mallofre
A
A
Serrano
J
J
Suñol
J
J
Barja
M
M
Ubach
D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000737:chemistry / Q000235:genetics*; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D011379:Prognosis; D012189:Retrospective Studies
D004273:DNA, Neoplasm