Neurovascular considerations in surgery of glomus tumors with intracranial extensions.
Paragangliomas of the skull base, by virtue of their location, locally infiltrative behavior, and vascular nature, are difficult tumors to resect. Surgical removal is especially complicated when intracranial extensions are encountered. Our experience with a one-stage resection of intracranial extensions of glomus tumors in 20 patients is presented. These 20 patients had a total of 29 paragangliomas: 23 glomus jugulare or tympanicum tumors, 5 carotid body tumors, and 1 pterygopalatine lesion. Ten patients had intradural extension; the other 10 had intracranial extradural tumors. The primary complicating treatment factor was the loss of surgical planes in 6 patients with prior surgery and or radiotherapy. The presence of multiple paragangliomas (20%) and catecholamine secretion by the tumors (15%) complicated surgical treatment as well. Surgical morbidity was primarily related to deficits of lower cranial nerves (50%).
Division of Otolaryngology, University of Mississippi Medical Center, Jackson 39216.
V K
VK
Anand
J P
JP
Leonetti
O
O
al-Mefty
D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology; D002343:Carotid Artery, Internal / Q000473:pathology; D005260:Female; D005925:Glomus Jugulare Tumor / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005918:Glomus Tumor / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011183:Postoperative Complications