Growth factors and growth factor receptors.
Peptide growth factors and their cell surface-associated receptors are important determinants of normal and pathological growth reactions. Through signal transduction pathways, receptor occupancy triggers the production of intracellular downstream effector molecules which ultimately cause cell proliferation.
Alison
M R
MR
Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Wright
N A
NA
D002450:Cell Communication; D002455:Cell Division; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D011956:Receptors, Cell Surface / Q000502:physiology*; D015398:Signal Transduction
D006133:Growth Substances; D011956:Receptors, Cell Surface