Atypical renal adenocarcinoma with features suggesting collecting duct origin and mimicking a mucinous adenocarcinoma.
We report a case of an atypical renal adenocarcinoma of the renal medulla associated with a marked desmoplastic response and interstitial mucin production. Collecting duct epithelium of the renal medulla throughout the kidney showed cytologic atypia. These features have been described by others as suggestive of a collecting duct histogenesis. This case represents the fifteenth reported case known to us of a renal adenocarcinoma of collecting duct origin. Prior reports, however, have not described the extensive mucin production that may be associated.
Milton S. Hershey Medical Center, Pennsylvania State University, Hershey.
G
G
Halenda
J N
JN
Sees
J A
JA
Belis
T J
TJ
Rohner
D000230:Adenocarcinoma / Q000175:diagnosis*; D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis*; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007679:Kidney Medulla; D007680:Kidney Neoplasms / Q000175:diagnosis*; D007685:Kidney Tubules, Collecting / Q000473:pathology*