Elastin metabolism parameters in sera of patients with lung cancer.
Elastin metabolism parameters (elastin-derived peptides and elastase-like activity) were determined in sera of patients with lung cancer and in healthy controls. The concentration of elastin-derived peptides was statistically significantly elevated in the lung cancer group. There was no statistically significant difference in the serum elastase-like activity between the groups studied. These data seem to indicate an enhanced metabolism of elastin in patients with lung cancer.
Gmiński
J
J
Department of Biochemistry and Chemistry, Silesian Medical Academy, Katowice, Poland.
Mykala-Cieśla
J
J
Machalski
M
M
Drózdz
M
M
D000230:Adenocarcinoma / Q000097:blood*; D018288:Carcinoma, Small Cell / Q000097:blood*; D002294:Carcinoma, Squamous Cell / Q000097:blood*; D004549:Elastin / Q000097:blood / Q000302:isolation & purification / Q000378:metabolism*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010196:Pancreatic Elastase / Q000097:blood; D010446:Peptide Fragments / Q000097:blood
D010446:Peptide Fragments; D004549:Elastin; D010196:Pancreatic Elastase