Superoxide generated by cigarette smoke damages the respiratory burst and induces physical changes in the membrane order and water organization of inflammatory cells.
Department of Molecular and Cell Biology, University of California, Berkeley 94720.
M
M
Tsuchiya
Y J
YJ
Suzuki
C E
CE
Cross
L
L
Packer
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001834:Body Water / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D009504:Neutrophils / Q000378:metabolism* / Q000648:ultrastructure; D010101:Oxygen Consumption / Q000187:drug effects; D010947:Plants, Toxic; D051381:Rats; D017207:Rats, Sprague-Dawley; D016897:Respiratory Burst / Q000187:drug effects; D012906:Smoke / Q000009:adverse effects*; D013482:Superoxide Dismutase / Q000494:pharmacology; D013481:Superoxides / Q000378:metabolism*; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism; D013997:Time Factors; D014026:Nicotiana; D014407:Tumor Cells, Cultured
D000975:Antioxidants; D005609:Free Radicals; D012906:Smoke; D013481:Superoxides; D013482:Superoxide Dismutase