Reye syndrome associated with subclinical varicella zoster virus and influenza A infection.
An association is reported between Reye syndrome and varicella zoster virus (VZV) infection in a 10-year-old boy who had serologic evidence of coinfection with VZV and influenza A H3N2, and exposure to salicylates. He developed VZV reinfection without skin lesions after family exposure and influenza A was community-acquired. Recent chickenpox contact should initiate VZV serologic studies in Reye syndrome patients, regardless of the chickenpox history or evidence of infection with other viruses.
Hukin
J
J
Department of Pediatrics, University of British Columbia, Vancouver, Canada.
Junker
A K
AK
Thomas
E E
EE
Farrell
K
K
D000596:Amino Acids / Q000097:blood; D000641:Ammonia / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects; D002648:Child; D006562:Herpes Zoster / Q000175:diagnosis* / Q000188:drug therapy; D014645:Herpesvirus 3, Human / Q000276:immunology; D006801:Humans; D009980:Influenza A virus / Q000276:immunology / Q000302:isolation & purification; D007251:Influenza, Human / Q000175:diagnosis* / Q000188:drug therapy; D008111:Liver Function Tests; D008297:Male; D009460:Neurologic Examination / Q000187:drug effects; D012202:Reye Syndrome / Q000139:chemically induced / Q000175:diagnosis*
D000596:Amino Acids; D000914:Antibodies, Viral; D000641:Ammonia; D001241:Aspirin