Effect of surgical repair on the neurologic function in infants with lipomeningocele.
Eighteen children under the age of 1 year underwent surgery for lipomeningocele at our institution between 1983 and 1991. All the patients had neurologic exams and urodynamic studies (UDS) including a cystometrogram and electromyography of the external urethral sphincter pre- and postoperatively. The surgical procedure performed included an untethering of the spinal cord, laser debulking of the lipoma and placement of a dural graft. All the infants presented with a lesion on their back. Two of 10 infants with a normal neurological exam had abnormal UDS preoperatively. Early surgery normalized abnormal preoperative UDS in 5 of 6 (83%) infants with abnormal UDS. Moreover, 3 of 8 (38%) infants with an abnormal neurological exam preoperatively improved after surgery and none worsened. These observations suggest that abnormal urinary tract function in infants with lipomeningocele may be reversible with early prophylactic surgery.
Department of Neurosurgery, Children's Hospital, Boston, MA 02115.
S
S
Sathi
J R
JR
Madsen
S
S
Bauer
R M
RM
Scott
D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000151:congenital / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000002:abnormalities / Q000601:surgery; D008297:Male; D008588:Meningocele / Q000601:surgery*; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis*; D012189:Retrospective Studies; D012447:Sacrum / Q000002:abnormalities / Q000601:surgery; D013125:Spinal Neoplasms / Q000151:congenital / Q000601:surgery*; D001750:Urinary Bladder, Neurogenic / Q000175:diagnosis; D014563:Urodynamics / Q000502:physiology