Cardiac dysrhythmia in total thoracic oesophagectomy. A prospective study.
A prospective controlled randomized clinical study of 50 patients undergoing total thoracic oesophagectomy by one surgical team is described, in which one group of patients was given prophylactic digoxin and the other was not. The incidence of cardiac dysrhythmia in each group was compared. Fourteen (56%) of 25 patients digitalized, compared to 16 (64%) of 25 patients not digitalized, suffered cardiac dysrhythmia, with a total incidence of 30 patients (60%). The first onset of dysrhythmia occurred within 48 h in 89% of the patients who suffered this complication. These results indicate a high incidence of cardiac dysrhythmia in patients undergoing this operative procedure, which is not significantly reduced by prophylactic digitalization and which is likely to occur within 2 days of surgery.
Northern Ireland Regional Thoracic Surgical Department, Royal Victoria Hospital, Belfast, UK.
A J
AJ
Ritchie
M
M
Whiteside
M
M
Tolan
J A
JA
McGuigan
D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology* / Q000517:prevention & control; D004077:Digoxin / Q000627:therapeutic use*; D016629:Esophagectomy / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D011292:Premedication; D011446:Prospective Studies
D004077:Digoxin