Effects of a porcine somatotropin implant on tissue mineral status of finishing pigs exposed to a thermoneutral or cold environment.
An experiment was conducted with 24 crossbred (Landrace x Yorkshire x Duroc) finishing pigs (mean BW 85 kg) to study the effects of a single 100-mg recombinant porcine somatotropin (rpST) implant on the tissue mineral status of pigs exposed to either a thermoneutral (TN; 18 to 21 degrees C, 50 to 55% RH) or cold (C; 5 to 15 degrees C, 50 to 70% RH) environment until BW averaged 110 kg. The implants used in this study delivered an average 2.4 to 2.5 mg of rpST/d during the course of the study. Control pigs were implanted with a placebo. All diets were supplemented with minerals at levels that either met or exceeded the requirements of an 85-kg pig. At slaughter (mean BW 110 kg), tissues were collected and analyzed for selected macro- and microminerals. Pigs treated with rpST had higher (P < .05) Ca concentrations and total Ca in liver and kidney and higher (P < .05) Ca concentrations in muscle. Total P, Mg, Na, and K were all higher (P < .05) in the liver and kidneys of rpST-treated pigs. In general, rpST had little influence on Cu, Zn, and Fe in tissues. No consistent trend was evident in the response of tissue minerals to environmental temperature. Results indicated that pigs treated with rpST and supplemented with adequate minerals accumulated more minerals in certain tissues than did pigs not given rpST.
Department of Animal Science, University of Missouri, Columbia 65211.
D R
DR
Ledoux
C D
CD
Knight
B A
BA
Becker
C A
CA
Baile
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D004343:Drug Implants; D005260:Female; D013006:Growth Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D008903:Minerals / Q000008:administration & dosage / Q000493:pharmacokinetics*; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000494:pharmacology; D013154:Spleen / Q000378:metabolism; D013552:Swine / Q000254:growth & development / Q000378:metabolism*; D013696:Temperature; D014018:Tissue Distribution / Q000187:drug effects; D015430:Weight Gain / Q000187:drug effects
D004343:Drug Implants; D008903:Minerals; D011994:Recombinant Proteins; D013006:Growth Hormone