Surveillance in patients with stage I testicular nonseminomatous germ cell tumors.
Fourteen patients with testicular nonseminomatous germ cell tumor, clinical stage I were entered into a surveillance study. Median age was 31 (range 18-58). Three patients had pure tumor, and 11, mixed tumor. In 2 patients, vascular invasion was noted, and in 1, involvement of the spermatic cord. Serum alpha fetoprotein and beta subunit choriogonadotropin were high in 9 and in 3 patients, respectively. In median follow-up of 21 months (range 2-63), 3 patients relapsed: 1 had inguinal lymphadenopathy and 2 had lung metastases at 12, 4, and 16 months, respectively. Salvage chemotherapy PEB and PVB achieved complete response in the latter 2 patients for 6 and 49 months. Except for 1 patient lost to follow-up, all are alive.
Gez
E
E
Hadassah University Hospital, Jerusalem, Israel.
Wygoda
M
M
Nussbaum
N
N
Figer
A
A
Gil
R I
RI
Inbal
M
M
D000293:Adolescent; D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D009919:Orchiectomy; D011446:Prospective Studies; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*