Congenital aortic stenosis and pregnancy--a reappraisal.
OBJECTIVE
This study was performed to determine the maternal and fetal outcome in pregnant patients with congenital aortic stenosis without previous valvular replacement.


METHODS
A retrospective review of 25 pregnancies in 13 patients delivered at our centers from September 1976 to September 1992 was undertaken.


RESULTS
Five (38%) patients had associated congenital heart lesions, three (23%) had severe stenosis (echocardiographically estimated valve area < or = 0.7 cm2), two had prior open aortic valve commissurotomy, and one had balloon valvuloplasty during pregnancy. There were no maternal deaths. Of the 25 pregnancies, five (20%) resulted in therapeutic abortions. There was no perinatal mortality, preterm labor, or increased incidence of pregnancy complications or fetal growth retardation in the remaining 20 pregnancies. One infant (5%) had congenital heart disease.


CONCLUSIONS
Pregnancy outcome is generally satisfactory in patients with congenital aortic stenosis.
Special Pregnancy Unit, Toronto Hospital, Ontario, Canada.
T T
TT
Lao
M
M
Sermer
L
L
MaGee
D
D
Farine
J M
JM
Colman
D000293:Adolescent; D000328:Adult; D001024:Aortic Valve Stenosis / Q000150:complications* / Q000151:congenital / Q000601:surgery; D004452:Echocardiography; D005260:Female; D005313:Fetal Death; D006801:Humans; D008428:Maternal Mortality; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000601:surgery; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D016276:Ventricular Function