[The action of bilirubin in vitro on the antioxidant activity and lipid peroxidation of the plasma and erythrocytes of cord blood].
Plasma and erythrocytes of cord blood were incubated with bilirubin (40-400 mkMol/l) for 30 min. This incubation resulted in reduction of lipid peroxidation both in plasma and erythrocytes. The antioxidant activity increased in erythrocytes after incubation, but decreased in plasma. It concluded that high concentration of protein-bound bilirubin and about its effect exerted an antioxidant effect and could influence the stability of blood cells.
Burmistrov
S O
SO
Dubinina
E E
EE
Shabalov
N P
NP
Khodov
D A
DA
Talabi
E
E
D000975:Antioxidants; D001663:Bilirubin / Q000494:pharmacology*; D002374:Catalase / Q000097:blood / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D005312:Fetal Blood / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D015227:Lipid Peroxidation / Q000187:drug effects*; D010949:Plasma / Q000187:drug effects* / Q000378:metabolism
D000975:Antioxidants; D002374:Catalase; D001663:Bilirubin