A UV-sensitive mutant of Arabidopsis defective in the repair of pyrimidine-pyrimidinone(6-4) dimers.
Plants are continually subjected to ultraviolet-B (UV-B) irradiation (290 to 320 nanometers) as a component of sunlight, which induces a variety of types of damage to the plant DNA. Repair of the two major DNA photoproducts was analyzed in wild-type Arabidopsis thaliana and in a mutant derivative whose growth was sensitive to UV-B radiation. In wild-type seedlings, repair of cyclobutane pyrimidine dimers occurred more slowly in the dark than in the light; repair of this photoproduct was not affected in the mutant. Repair, in the dark, of pyrimidine-pyrimidinone(6-4) dimers was defective in the UV-sensitive mutant.
Britt
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AB
Section of Botany, University of California at Davis 95616.
Chen
J J
JJ
Wykoff
D
D
Mitchell
D
D
D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000528:radiation effects; D004260:DNA Repair; D003624:Darkness; D008027:Light; D009154:Mutation; D011740:Pyrimidine Dimers / Q000378:metabolism*; D014466:Ultraviolet Rays
D011740:Pyrimidine Dimers