Regulation of energy expenditure in aging humans.
The regulation of daily energy expenditure and its components in aging humans in considered in this review. Specifically, the effects of age on resting metabolic rate (RMR), the thermic effect of a meal, body composition, and the interaction of these variables with physical activity in both men and women are considered. The possible modulators of the age-related decline in RMR are examined by exploring the influence of alterations in body composition, physical activity, and the sodium-potassium pump. Thereafter, the status of energy requirements in healthy and diseased individuals is examined. New information is presented regarding the use of the doubly-labeled water technique to measure daily energy expenditure and its applicability to the determination of daily energy requirements in free-living older persons.
Department of Medicine, University of Vermont, Burlington 05405.
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Poehlman
D000273:Adipose Tissue / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism*; D000544:Alzheimer Disease / Q000378:metabolism; D001481:Basal Metabolism; D001794:Blood Pressure; D001823:Body Composition; D004034:Diet Surveys; D002149:Energy Intake; D004734:Energy Metabolism; D015444:Exercise; D005260:Female; D005502:Food; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D010101:Oxygen Consumption; D011237:Predictive Value of Tests; D012727:Sex Characteristics; D000254:Sodium-Potassium-Exchanging ATPase
D000254:Sodium-Potassium-Exchanging ATPase