Standardization of protein immunoprocedures. Choriogonadotropin (CG).
The objectives of this report is to improve the quality of immunochemical determinations of proteins. Procedures for determination of the various molecular forms hCG were chosen as the subject of a detailed study, with the aim as using this report as a model for similar future projects. The aim of this undertaking is to improve the reliability and reproducibility of the results and, as a result of this, to enhance the clinical usefulness of hCG determinations. The following means will be used to achieve these goals: (a) establishing uniform nomenclature and abbreviations for various molecular forms of hCG, (b) preparation of new calibrators for these and establishing of methods for determining the amount of substance concentration in mol/L, (c) improving quality assessment materials and procedures, (d) definition of methods for characterization of hCG measurement procedures.
Stenman
U H
UH
Helsinki University Central Hospital, FI.
Bidart
J M
JM
Birken
S
S
Mann
K
K
Nisula
B
B
O'Connor
J
J
D000918:Antibody Specificity; D006063:Chorionic Gonadotropin / Q000032:analysis* / Q000276:immunology; D003429:Cross Reactions; D006801:Humans; D007118:Immunoassay / Q000592:standards*; D007986:Luteinizing Hormone / Q000276:immunology; D012015:Reference Standards; D012016:Reference Values; D012680:Sensitivity and Specificity; D013048:Specimen Handling; D009626:Terminology as Topic
D006063:Chorionic Gonadotropin; D007986:Luteinizing Hormone