Calcitonin-testosterone interrelationship. A classic feedback system?
Calcitonin infusion in pharmacological doses reduces the serum concentration of testosterone, LH and FSH, probably by acting at the hypothalamic level. This fact, in combination with the well-known calcitonin stimulating effect of testosterone, suggests that calcitonin and testosterone are possibly acting as a classic negative feedback system.
Department of Internal Medicine, Ijsselland Hospital, Capelle a.d. Ijssel, Netherlands.
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Mulder
D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000494:pharmacology*; D002116:Calcitonin / Q000008:administration & dosage / Q000494:pharmacology*; D004341:Drug Evaluation; D005246:Feedback; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007031:Hypothalamus / Q000187:drug effects; D007275:Injections, Intravenous; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects; D012965:Sodium Chloride / Q000008:administration & dosage / Q000494:pharmacology; D013739:Testosterone / Q000097:blood*
D000700:Analgesics; D013739:Testosterone; D012965:Sodium Chloride; C028815:salmon calcitonin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D002116:Calcitonin