[Expression pattern of fibroblast growth factor receptor 1 gene during chick eye development].
To reveal the expression pattern of fibroblast growth factor receptor 1 (FGFR1) gene during chick eye development, in situ hybridization was performed on sections of chick embryo from stage 8 to 28. At stage 8 and 10, transcripts of FGFR1 were observed over the whole embryo and they were located at the optic cup, the lens vesicle, the orbital mesenchyme and the neuroepithelium of the diencephalon at stage 17. In the inner layer of the optic cup at stage 21, the expression was restricted to the anterior portion. It was suggested that FGFR1 expression was involved in chick eye development, especially in determination of anterior-posterior axis of the eye.
Department of Ophthalmology, Okayama University Medical School, Japan.
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Ohuchi
D000818:Animals; D002642:Chick Embryo; D005123:Eye / Q000196:embryology*; D015870:Gene Expression; D017403:In Situ Hybridization; D020794:Receptor Protein-Tyrosine Kinases; D051496:Receptor, Fibroblast Growth Factor, Type 1; D011956:Receptors, Cell Surface / Q000235:genetics*; D017468:Receptors, Fibroblast Growth Factor; D013997:Time Factors
D011956:Receptors, Cell Surface; D017468:Receptors, Fibroblast Growth Factor; D020794:Receptor Protein-Tyrosine Kinases; D051496:Receptor, Fibroblast Growth Factor, Type 1