[A clinical study on cefditoren pivoxil in pediatrics].
Clinical evaluations of cefditoren pivoxil (CDTR-PI, ME 1207) in granules were carried out. The obtained results are summarized as follows. 1. Thirty-nine patients with pediatric infections were treated with CDTR-PI. Clinical responses of 36 assessable cases were excellent in 25, good in 9 and fair in 2. The overall efficacy rate was 94%. 2. Bacteriologically, 30 of the 31 identified bacteria presumed to be pathogens were eradicated and the eradication rate was 97%. 3. Side effects observed were diarrhea in 3 of 39 patients. The incidence was 7.7%. Abnormal laboratory test results were not observed. The results suggested that CDTR-PI might be a very useful and safe drug for the treatment of pediatric infections.
Department of Pediatrics, Ohta General Hospital.
Y
Y
Satoh
S
S
Iwata
H
H
Akita
T
T
Aoyama
Y
Y
Takeuchi
T
T
Yokota
K
K
Sunakawa
D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002511:Cephalosporins / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D012541:Scarlet Fever / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000188:drug therapy*
D002511:Cephalosporins; C057710:cefditoren pivoxil