N-acetylglucosamine-1-phosphate transferase gene is conserved in five Leishmania spp. and overexpressed due to its amplification in their tunicamycin-resistant variants.
Liu
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Department of Microbiology and Immunology, University of Health Sciences/Chicago Medical School, IL.
Chang
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D000818:Animals; D001483:Base Sequence; D017124:Conserved Sequence; D016054:DNA, Protozoan / Q000235:genetics; D004351:Drug Resistance / Q000235:genetics; D005784:Gene Amplification; D015870:Gene Expression; D017125:Genes, Protozoan; D014644:Genetic Variation; D007891:Leishmania / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics*; D008969:Molecular Sequence Data; D010770:Phosphotransferases / Q000235:genetics*; D013045:Species Specificity; D017855:Transferases (Other Substituted Phosphate Groups); D014415:Tunicamycin / Q000494:pharmacology
D016054:DNA, Protozoan; D014415:Tunicamycin; D010770:Phosphotransferases; D017855:Transferases (Other Substituted Phosphate Groups); C023222:UDPacetylglucosamine-dolichyl-phosphate acetylglucosamine-1-phosphate transferase