The distribution and interrelationship of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, and BANA scores among older adults.
In a random sample of subgingival dental plaque samples from 375 blacks and 300 whites aged 65 and older, immunofluorescence assays for 3 target pathogens including Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Prevotella intermedia, and BANA enzyme analysis were carried out. Blacks had significantly greater proportions of P. gingivalis and P. intermedia in their subgingival plaque and had significantly higher BANA scores. These assay results were investigated for concordance with each other and with 2 cariogenic salivary bacteria, Streptococcus mutans and lactobacilli. In general for both races, the periodontal pathogens were more likely to occur in combination with each other than with either S. mutans or lactobacilli. P. gingivalis and P. intermedia were more frequently associated with each other than with A. actinomycetemcomitans. There was a significant negative concordance between BANA and A. actinomycetemcomitans in whites and a significant positive concordance between BANA and P. intermedia in blacks.
Department of Diagnostic Sciences, University of North Carolina, Chapel Hill.
C W
CW
Drake
R J
RJ
Hunt
J D
JD
Beck
J J
JJ
Zambon
D001741:Black or African American; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification*; D001439:Bacteroides / Q000302:isolation & purification*; D001587:Benzoylarginine-2-Naphthylamide / Q000378:metabolism; D016009:Chi-Square Distribution; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000208:ethnology / Q000382:microbiology*; D005260:Female; D015200:Fluoroimmunoassay; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009657:North Carolina; D016017:Odds Ratio; D010510:Periodontal Diseases / Q000382:microbiology; D016966:Porphyromonas gingivalis / Q000302:isolation & purification*; D015995:Prevalence; D012307:Risk Factors; D044465:White People
D001587:Benzoylarginine-2-Naphthylamide