Primary hepatic vipoma.
A 35-yr-old male presented with a 3-yr history of voluminous watery diarrhea. He had episodes of severe generalized weakness which responded to fluid and electrolyte replacement therapy. Investigations revealed a solitary liver mass and an elevated vasoactive intestinal polypeptide level. An extensive work-up did not show any other extrahepatic primary lesion. Surgical resection ameliorated all of his symptoms, accompanied by a decrease in the vasoactive intestinal polypeptide level. We believe that this patient represents a case of primary hepatic vipoma syndrome. To our present knowledge, this has not been reported previously. We discuss the clinical manifestations, investigations, and management of the case.
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
A
A
Ayub
M
M
Zafar
A
A
Abdulkareem
M A
MA
Ali
T
T
Lingawi
A
A
Harbi
D000328:Adult; D001706:Biopsy; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D008297:Male; D015282:Octreotide / Q000627:therapeutic use; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism; D003969:Vipoma / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy
D014660:Vasoactive Intestinal Peptide; D015282:Octreotide