Dog genetic polymorphism revealed by synthetic tandem repeats.
We are studying the genetic polymorphism associated with Variable Number of Tandem Repeat (VNTR) loci in 13 breeds of dogs, namely: Alaskan Malamute, Barzoi, Beagle, Belgian Shepherd, Fox Terrier, Griffon, Labrador, Irish Setter, Spaniel, Dachshund, Irish Terrier, Shar Pei and Poodle. Our approach is based upon synthetic tandem repeats (STRs). Using a panel of these arbitrary unit polymers to detect minisatellites, we are attempting to develop paternity testing systems on pure bred dog pedigrees. We are evaluating the potential importance of STRs as a tool for the isolation of minisatellites in dogs, as well as for the characterization of dog genetic markers.
URA-INRA de Génétique Moléculaire, Ecole Nationale Vétérinaire de Maisons-Alfort, France.
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Mariat
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Robert
D000818:Animals; D001483:Base Sequence; D016172:DNA Fingerprinting; D015342:DNA Probes / Q000235:genetics; D004276:DNA, Satellite / Q000235:genetics; D004285:Dogs / Q000235:genetics*; D005260:Female; D005819:Genetic Markers; D008297:Male; D008969:Molecular Sequence Data; D010334:Paternity; D010375:Pedigree; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D013045:Species Specificity
D015342:DNA Probes; D004276:DNA, Satellite; D005819:Genetic Markers