Primary hepatic vipoma.
A 35-yr-old male presented with a 3-yr history of voluminous watery diarrhea. He had episodes of severe generalized weakness which responded to fluid and electrolyte replacement therapy. Investigations revealed a solitary liver mass and an elevated vasoactive intestinal polypeptide level. An extensive work-up did not show any other extrahepatic primary lesion. Surgical resection ameliorated all of his symptoms, accompanied by a decrease in the vasoactive intestinal polypeptide level. We believe that this patient represents a case of primary hepatic vipoma syndrome. To our present knowledge, this has not been reported previously. We discuss the clinical manifestations, investigations, and management of the case.
Ayub
A
A
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Zafar
M
M
Abdulkareem
A
A
Ali
M A
MA
Lingawi
T
T
Harbi
A
A
D000328:Adult; D001706:Biopsy; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D008297:Male; D015282:Octreotide / Q000627:therapeutic use; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism; D003969:Vipoma / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy
D014660:Vasoactive Intestinal Peptide; D015282:Octreotide