UCE6, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from actinomycetes.
N
N
Fujii
Y
Y
Yamashita
S
S
Chiba
Y
Y
Uosaki
Y
Y
Saitoh
Y
Y
Tuji
H
H
Nakano
D000192:Actinomycetales / Q000378:metabolism*; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis / Q000494:pharmacology*; D002417:Cattle; D004249:DNA Damage / Q000187:drug effects*; D004264:DNA Topoisomerases, Type I / Q000187:drug effects*; D006801:Humans; D011809:Quinones / Q000378:metabolism / Q000494:pharmacology*
D000903:Antibiotics, Antineoplastic; D011809:Quinones; C082796:UCE6; D004264:DNA Topoisomerases, Type I