Mammographic aspect, cell kinetics and hormone receptor status of operable breast cancer.
To investigate the relationships between the mammographic aspects (according to Broberg), proliferative activity and hormone receptor status, we studied 165 patients subjected to radical mastectomy for operable breast cancer. The highest percentage of estrogen receptor-positive cases was observed in mammograph class I (p < 0.02) while classes III and V were highest in progesterone receptor-positive cases. Proliferative activity (111 cases) was significantly lower in class I and IV with respect to all other classes (p < 0.03 and p < 0.01, respectively). This study suggests that certain mammographic signs can be related to the biological characteristics of breast cancer.
Paradiso
A
A
Medical Oncology Division, Oncology Institute, Bari, Italy.
Ventrella
V
V
Farchi
G
G
Tommasi
S
S
Mangia
A
A
Barletta
A
A
Schittulli
F
F
Racanelli
A
A
De Lena
M
M
D001943:Breast Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000145:classification / Q000473:pathology* / Q000601:surgery; D002453:Cell Cycle; D002455:Cell Division / Q000502:physiology; D005260:Female; D006801:Humans; D008327:Mammography; D009367:Neoplasm Staging; D009376:Neoplasms, Hormone-Dependent / Q000145:classification / Q000473:pathology* / Q000601:surgery; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D014316:Tritium; D013936:Thymidine