Comparison between methods for human papillomavirus DNA testing: a model for self-testing in young women.
This study examined the accuracy of samples obtained by women with Dacron swabs for testing for human papillomavirus (HPV). A total of 114 women obtained samples with the swabs and then had routine pelvic examinations done by nurse practitioners during which endocervical and exocervical samples were obtained by speculum-assisted technique. These samples were used for HPV DNA testing and cytology. The results of both sets of samples were compared. A total of 104 samples (91%) obtained by self-sampling were concordant with those obtained by speculum-assisted technique. Thus, self-sampling with a Dacron swab appears to be an accurate and noninvasive method for obtaining samples for HPV DNA testing.
Department of Pediatrics, University of California, San Francisco.
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Moscicki
D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D015151:Immunoblotting; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D016353:Self-Examination; D014412:Tumor Virus Infections / Q000175:diagnosis*; D014626:Vaginal Smears / Q000379:methods*
D015344:DNA Probes, HPV; D004279:DNA, Viral