Depression of plasma cholesterol in men by consumption of baked products containing soy protein.
The effects of soy-protein consumption with and without soy fiber on plasma lipids in 26 mildly hypercholesterolemic men were studied. Four, 4-wk dietary treatments included 50 g protein and 20 g dietary fiber from soy flour (SF), isolated soy protein/soy cotyledon fiber (ISP/SCF), ISP/cellulose (ISP/C), or nonfat dry milk/C (NFDM/C) in conjunction with a low-fat, low-cholesterol diet. Plasma total cholesterol (TC) concentrations were lowest for both ISP dietary treatments compared with baseline (P < 0.05) and NFDM/C (P < 0.01). SF also led to lower TC compared with NFDM/C (P < 0.05). LDL-cholesterol values were lowest for both ISP treatments compared with NFDM/C (P < 0.01), but lower compared with baseline only with ISP/SCF (P < 0.05). Apolipoprotein B was lowest when ISP/C was fed, compared with baseline, SF, and NFDM (P < 0.05). HDL-cholesterol and total triglycerides (TG) were not affected. Results indicate that 50 g ISP is effective in lowering TC, LDL-C, and apolipoprotein B while maintaining HDL concentrations in mildly hypercholesterolemic men.
Potter
S M
SM
Department of Food Science, University of Illinois at Urbana-Champaign.
Bakhit
R M
RM
Essex-Sorlie
D L
DL
Weingartner
K E
KE
Chapman
K M
KM
Nelson
R A
RA
Prabhudesai
M
M
Savage
W D
WD
Nelson
A I
AI
Winter
L W
LW
D000328:Adult; D001053:Apolipoproteins / Q000378:metabolism; D002784:Cholesterol / Q000097:blood*; D003296:Cooking; D004044:Dietary Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014674:Plant Proteins, Dietary / Q000008:administration & dosage / Q000494:pharmacology*; D030262:Soybean Proteins; D014280:Triglycerides / Q000097:blood
D001053:Apolipoproteins; D004044:Dietary Proteins; D014674:Plant Proteins, Dietary; D030262:Soybean Proteins; D014280:Triglycerides; D002784:Cholesterol