GC/MS identification of tetramine in samples from human alimentary intoxication and evaluation of artificial carbonic kidneys for the treatment of the victims.
One day in July 1991, 78 people became victims of accidental alimentary intoxication in a factory in Hebei Province, China. Related samples, including rodenticide bait, the artificial carbonic kidneys used for the treatment of the victims, and the victims' blood, were analyzed by GC/MS. Tetramine [80-12-6], a highly toxic rodenticide, was identified as the toxicant. The effectiveness of artificial carbonic kidneys was evaluated. The analytical results revealed that detoxification of the patients was effective 48 hours after intoxication by percolating their blood through artificial carbonic kidneys.
Institute of Toxicology and Pharmacology, Beijing, P.R., China.
F Y
FY
Guan
Y T
YT
Liu
Y
Y
Luo
X Y
XY
Hu
F
F
Liu
Q Y
QY
Li
Z W
ZW
Kang
D001952:Bridged-Ring Compounds / Q000032:analysis* / Q000506:poisoning*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007688:Kidneys, Artificial; D011041:Poisoning / Q000628:therapy; D012378:Rodenticides / Q000032:analysis*
D001952:Bridged-Ring Compounds; D012378:Rodenticides; C010349:tetramethylenedisulfotetramine