Superoxide generated by cigarette smoke damages the respiratory burst and induces physical changes in the membrane order and water organization of inflammatory cells.
Tsuchiya
M
M
Department of Molecular and Cell Biology, University of California, Berkeley 94720.
Suzuki
Y J
YJ
Cross
C E
CE
Packer
L
L
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001834:Body Water / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D009504:Neutrophils / Q000378:metabolism* / Q000648:ultrastructure; D010101:Oxygen Consumption / Q000187:drug effects; D010947:Plants, Toxic; D051381:Rats; D017207:Rats, Sprague-Dawley; D016897:Respiratory Burst / Q000187:drug effects; D012906:Smoke / Q000009:adverse effects*; D013482:Superoxide Dismutase / Q000494:pharmacology; D013481:Superoxides / Q000378:metabolism*; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism; D013997:Time Factors; D014026:Nicotiana; D014407:Tumor Cells, Cultured
D000975:Antioxidants; D005609:Free Radicals; D012906:Smoke; D013481:Superoxides; D013482:Superoxide Dismutase