Sequence and expression of a Drosophila melanogaster cDNA encoding a putative ribosomal protein.
An abundant ovarian cDNA from Drosophila melanogaster has been cloned and sequenced. The predicted protein sequence is similar to that of the ribosomal protein 1024 of Dictyostelium discoideum, the 40S ribosomal protein ys11 of Saccharomyces cerevisiae and a 22 kd protein from Trypanosoma brucei. It seems, therefore, that the Drosophila cDNA also encodes a ribosomal protein. Transcripts are found at all stages of the life cycle but are especially abundant in the ovary, suggesting that this mRNA is maternally stored for utilization in embryogenesis to enable the rapid production of ribosomal proteins and assembly of ribosomes.
Institute of Cell and Molecular Biology, University of Edinburgh, UK.
N
N
Zhang
M
M
Bownes
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary / Q000378:metabolism; D004023:Dictyostelium / Q000235:genetics; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D008297:Male; D008969:Molecular Sequence Data; D010053:Ovary / Q000378:metabolism; D012269:Ribosomal Proteins / Q000096:biosynthesis / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D014346:Trypanosoma brucei brucei / Q000235:genetics
D018076:DNA, Complementary; D012269:Ribosomal Proteins