Biochemical mechanisms underlying MPTP-induced and idiopathic parkinsonism. New vistas.
Singer
T P
TP
Molecular Biology Division, Department of Veterans Affairs Medical Center, San Francisco, California 94121.
Ramsay
R R
RR
Sonsalla
P K
PK
Nicklas
W J
WJ
Heikkila
R E
RE
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D000818:Animals; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology; D006801:Humans; D020267:MPTP Poisoning; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000037:antagonists & inhibitors; D009410:Nerve Degeneration / Q000187:drug effects / Q000502:physiology; D010084:Oxidation-Reduction; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000503:physiopathology; D013378:Substantia Nigra / Q000187:drug effects / Q000503:physiopathology; D013481:Superoxides / Q000378:metabolism
D013481:Superoxides; D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; D016660:NAD(P)H Dehydrogenase (Quinone)