[Therapy of pronounced pleural and pericardial effusion in metastatic breast cancer with local mitoxantrone and radiation therapy. Presentation of the intrapleural cytologic findings during this therapy].
The method of intrapleural Mitoxantrone therapy in case of metastasizing mammary cancer is presented in form of a case report. The uncomplicated procedure, the high rate of remission and the few side effects are the advantages as compared to other methods of pleurodesis. Mitoxantrone could cause an intrapleural inflammatory reaction. That is supported by the cytologic findings before and after the therapy.
Universitäts-Frauenklinik der Humboldt-Universität zu Berlin, Charité.
J U
JU
Blohmer
A
A
Kohls
H U
HU
Lau
D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008942:Mitoxantrone / Q000008:administration & dosage* / Q000009:adverse effects; D009367:Neoplasm Staging; D010490:Pericardial Effusion / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D010496:Pericardium / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects; D010994:Pleura / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects; D016066:Pleural Effusion, Malignant / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000473:pathology
D008942:Mitoxantrone