Dissemination of the TEM-I beta-lactamase gene into disparate plasmids in faecal strains of Escherichia coli isolated in Vellore, south India.
The genetic basis for ampicillin resistance in commensal strains of Escherichia coli isolated in Vellore, south India has been examined. Of the 58 strains tested, 41% could transfer ampicillin resistance to a standard E. coli host strain. With the exception of one isolate, transferable ampicillin resistance was shown to result from the presence of the TEM-I beta-lactamase which was found on a wide variety of plasmid types.
Department of Medical Microbiology, Medical School, University of Edinburgh, Scotland.
C J
CJ
Thomson
S
S
Tait
M V
MV
Jesudason
S G
SG
Amyes
D000668:Ampicillin Resistance / Q000235:genetics*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005243:Feces / Q000382:microbiology; D006801:Humans; D007194:India; D010957:Plasmids / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
D001618:beta-Lactamases; C034413:beta-lactamase TEM-1