Chemical study of the hepatotoxins from Microcystis aeruginosa collected in California.
Four cyclic peptide toxins were purified and quantified from the aqueous extract of algal cell material utilizing high performance liquid chromatography, thin layer chromatography, and fast atom bombardment mass spectrometry. The cyclic peptide toxins appear to be similar structurally to hepatotoxins from previously identified blooms of the blue-green alga Microcystis aeruginosa.
Veterinary Medical Teaching Hospital, Department of Medicine, School of Veterinary Medicine, University of California, Davis 95616.
S E
SE
DeVries
M
M
Namikoshi
F D
FD
Galey
J E
JE
Merritt
K L
KL
Rinehart
V R
VR
Beasley
D000595:Amino Acid Sequence; D001427:Bacterial Toxins / Q000737:chemistry* / Q000302:isolation & purification; D002140:California; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D008387:Marine Toxins; D052998:Microcystins; D046931:Microcystis / Q000737:chemistry*; D008969:Molecular Sequence Data; D010456:Peptides, Cyclic / Q000032:analysis; D016339:Spectrometry, Mass, Fast Atom Bombardment
D001427:Bacterial Toxins; D008387:Marine Toxins; D052998:Microcystins; D010456:Peptides, Cyclic; C057862:cyanoginosin LR