[4'-Branched nucleosides. I. Synthesis of 3'-deoxy-3'-amino-4'-hydroxymethylnucleosides].
The condensation of 1, 2-di-O-acetyl-3-azido-3-deoxy-4-benzoyloxymethyl-1-5-O-benzoyl-bet a-D-ribofuranose with trimethylsilyl derivatives of N6-benzoyladenine, N4-acetylcytosine and uracil in the presence of stannic chloride led to the corresponding nucleosides. After deprotection with methanolic ammonia the azidonucleosides were reduced with PPh3 into 3'-amino-3'-deoxy-4'-hydroxymethynucleosides.
S A
SA
Surzhikov
N B
NB
Diatkina
D009682:Magnetic Resonance Spectroscopy; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D009705:Nucleosides