Comparative immunohistochemical demonstration of 1,25-dihydroxyvitamin D3 receptors in the vertebrate integument.
The study demonstrates 1,25-dihydroxyvitamin D3 receptors in the integument of different vertebrate groups, using a very sensitive streptavidin method. Positive reaction staining was confined to fibroblasts/fibrocytes in the dermis of those animals, which lacked strongly calcified or hardened tissue elements in this skin layer.
Meyer
W
W
Institut für Zoologie, Tierärztliche Hochschule Hannover, Germany.
D000818:Animals; D001426:Bacterial Proteins; D002113:Calcification, Physiologic; D002117:Calcitriol / Q000378:metabolism*; D005347:Fibroblasts / Q000737:chemistry; D018167:Receptors, Calcitriol; D011987:Receptors, Steroid / Q000032:analysis*; D012867:Skin / Q000033:anatomy & histology / Q000737:chemistry*; D013045:Species Specificity; D019809:Streptavidin; D014714:Vertebrates / Q000033:anatomy & histology / Q000378:metabolism*
D001426:Bacterial Proteins; D018167:Receptors, Calcitriol; D011987:Receptors, Steroid; D019809:Streptavidin; D002117:Calcitriol