Intestinal and pelvic endometriosis presenting as a tumor and associated with tamoxifen therapy: report of a case.
BACKGROUND
Tamoxifen has been used in the adjuvant treatment of breast cancer because of its antiestrogenic effects. However, recent reports have shown it to have estrogenic effects as well. The purpose of this report is to describe a potential association between tamoxifen therapy and endometriosis.


METHODS
A 50-year-old postmenopausal woman who had received 2 years of adjuvant tamoxifen therapy for breast carcinoma developed extensive tumor-like endometriosis necessitating extensive pelvic and intestinal surgery.


CONCLUSIONS
This case report highlights the need for obstetricians and gynecologists to be familiar with the actions of tamoxifen and its potential complications.
Department of Gynecology and Obstetrics, Henry Ford Medical Center, Detroit, Michigan.
L R
LR
Hajjar
W
W
Kim
G H
GH
Nolan
S
S
Turner
U R
UR
Raju
D001943:Breast Neoplasms / Q000188:drug therapy; D004715:Endometriosis / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000139:chemically induced* / Q000175:diagnosis; D008875:Middle Aged; D010386:Pelvic Neoplasms / Q000139:chemically induced* / Q000175:diagnosis; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use
D013629:Tamoxifen