Perturbation of the grasp component of a prehension movement in a subject with hemiParkinson's disease.
The response to perturbation of the manipulation component during prehension was assessed for both hands of a hemiParkinson and of a Control subject. With perturbed trials, the hemiParkinson showed the same pattern as the Control: a reorganization of kinematic parameters and no increase of movement time. However, for both limbs of the hemiParkinson subject there was a transition phase from precision grip to whole hand prehension--this was more pronounced for the affected limb. The manipulation component did not show a delay of activation [2]. Thus the global dysfunction in the performance of sequential movement patterns was related to aspects of task predictability.
Castiello
U
U
Dipartimento di Psicologia, Università di Bologna, Italy.
Bennett
K M
KM
Adler
C H
CH
Stelmach
G E
GE
D000368:Aged; D000978:Antiparkinson Agents / Q000009:adverse effects / Q000627:therapeutic use; D001288:Attention / Q000187:drug effects / Q000502:physiology; D004292:Dominance, Cerebral / Q000187:drug effects / Q000502:physiology*; D007839:Functional Laterality / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology*; D009949:Orientation / Q000187:drug effects / Q000502:physiology; D010300:Parkinson Disease / Q000188:drug therapy / Q000503:physiopathology*; D011597:Psychomotor Performance / Q000187:drug effects / Q000502:physiology*; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D012815:Signal Processing, Computer-Assisted
D000978:Antiparkinson Agents