[The arrest of hemorrhage in mechanical injuries to parenchymatous organs].
The work describes results of the application of a new highly effective hemostatic drug--Caprofer. The investigations were performed in 61 rabbits who were given graded injuries of the liver, kidney and spleen. In all the cases hemostasis made its appearance quickly within 1-20 sec. after the application of Caprofer. Reliability of hemostasis was checked by the method of hydropressure of the organs under study which was shown to be very high. Caprofer was used under clinical conditions in 61 patients in operations for traumas and diseases of the liver, kidney, spleen, gallbladder and in resection of the prostate. The results obtained speak of high efficiency of Caprofer for parenchymatous bleedings. Pronounced adhesive properties of the drug were noted as well as the absence of undesirable side effects.
A S
AS
Deviatov
S A
SA
Kalashnikov
E M
EM
Prokof'ev
D015119:Aminocaproic Acid / Q000008:administration & dosage / Q000009:adverse effects; D000818:Animals; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D005290:Ferric Compounds / Q000008:administration & dosage / Q000009:adverse effects; D006470:Hemorrhage / Q000188:drug therapy* / Q000473:pathology; D006488:Hemostasis, Surgical / Q000379:methods*; D006490:Hemostatics / Q000008:administration & dosage; D007431:Intraoperative Complications / Q000188:drug therapy* / Q000473:pathology; D007668:Kidney / Q000187:drug effects / Q000293:injuries / Q000601:surgery*; D008099:Liver / Q000187:drug effects / Q000293:injuries / Q000601:surgery; D011817:Rabbits; D013154:Spleen / Q000187:drug effects / Q000293:injuries / Q000601:surgery*
C043246:Amifer; D005290:Ferric Compounds; D006490:Hemostatics; D015119:Aminocaproic Acid