Identification of markers flanking the tuberous sclerosis locus on chromosome 9 (TSC1).
Analysis of a large tuberous sclerosis pedigree confirmed linkage to a locus on the long arm of chromosome 9, with recombination events placing the disease gene distal to gelsolin and proximal to dopamine beta-hydroxylase.
Institute of Medical Genetics, University Hospital of Wales, Heath Park, Cardiff.
M
M
Nellist
P T
PT
Brook-Carter
J M
JM
Connor
D J
DJ
Kwiatkowski
P
P
Johnson
J R
JR
Sampson
D000017:ABO Blood-Group System / Q000235:genetics; D002135:Calcium-Binding Proteins / Q000235:genetics; D002874:Chromosome Mapping; D002899:Chromosomes, Human, Pair 9; D004299:Dopamine beta-Hydroxylase / Q000235:genetics; D005260:Female; D018260:Gelsolin; D008040:Genetic Linkage; D005819:Genetic Markers; D006239:Haplotypes; D006801:Humans; D008297:Male; D008840:Microfilament Proteins / Q000235:genetics; D010375:Pedigree; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic; D014402:Tuberous Sclerosis / Q000235:genetics*
D000017:ABO Blood-Group System; D002135:Calcium-Binding Proteins; D018260:Gelsolin; D005819:Genetic Markers; D008840:Microfilament Proteins; D004299:Dopamine beta-Hydroxylase