Complete sequence of a bovine alpha-lactalbumin pseudogene: the region homologous to the gene is flanked by two directly repeated LINE sequences.
A 3-kb fragment hybridizing with a bovine alpha-lactalbumin cDNA probe was isolated from a bovine genomic library and completely sequenced. An internal fragment beginning downstream from exon 2, as already reported for another pseudogene, but ending in the 3'-untranslated region of exon 4 shares 78% sequence similarity with the bovine alpha-lactalbumin gene. This region is flanked by two directly repeated LINE sequences. The 5' ends of the fragment and of the aforementioned pseudogene share a specific nucleotide stretch, which suggests that they might have had a common origin.
Vilotte
J L
JL
Laboratoire de Génétique Biochimique, INRA-CRJ 78352, Jouy-en-Josas, France.
Soulier
S
S
Mercier
J C
JC
D025181:ATP Synthetase Complexes; D000818:Animals; D001483:Base Sequence; D002417:Cattle / Q000235:genetics*; D004247:DNA / Q000235:genetics; D007768:Lactalbumin / Q000235:genetics*; D008969:Molecular Sequence Data; D009097:Multienzyme Complexes / Q000235:genetics; D009113:Muramidase / Q000235:genetics; D010770:Phosphotransferases / Q000235:genetics; D011544:Pseudogenes; D012091:Repetitive Sequences, Nucleic Acid; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid
D009097:Multienzyme Complexes; D004247:DNA; D007768:Lactalbumin; D010770:Phosphotransferases; D025181:ATP Synthetase Complexes; D009113:Muramidase