A class-independent drug screen in forensic toxicology using a photodiode array detector.
A class-independent drug screen, that is suitable for use in clinical and forensic toxicology and uses gradient-elution high-performance liquid chromatography and photodiode array detection, is presented. The assay is capable of detecting and identifying therapeutic and toxic amounts of barbiturates, anti-convulsants, diuretics, non-steroidal anti-inflammatory drugs, sulfonylurea anti-diabetic drugs, theophylline, and analgesic drugs. The assay has been successfully used to screen over 1000 postmortem blood specimens.
Victorian Institute of Forensic Pathology, Monash University, South Melbourne, Australia.
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Drummer
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Kotsos
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McIntyre
D002851:Chromatography, High Pressure Liquid; D005554:Forensic Medicine; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D004364:Pharmaceutical Preparations