[An athrombogenic material based on modified polyethylene].
An athrombogenic material, exhibiting selective proteolytic activity, was developed. The material was obtained after modification of polyethylene by means of the polymer complex containing polyacrylic acid and E-caprolactam. The modified polyethylene was treated with thionyl chloride and then it was maintained in the solution containing streptokinase or urokinase. The athrombogenic material exhibited fibrinolytic activity within 15 days; its athrombogenic properties were studied in vitro.
M G
MG
Asadullin
A N
AN
Sadova
V P
VP
Glukhov
M V
MV
Borisova
D000180:Acrylic Resins / Q000737:chemistry; D002209:Caprolactam / Q000737:chemistry; D006868:Hydrolysis; D011095:Polyethylenes / Q000737:chemistry / Q000627:therapeutic use*; D013300:Streptokinase; D013927:Thrombosis / Q000628:therapy*; D014568:Urokinase-Type Plasminogen Activator
D000180:Acrylic Resins; D011095:Polyethylenes; C006903:carbopol 940; D002209:Caprolactam; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator