[The effect of transcardiac galvanization on the function of the microcirculatory bed of the peri-infarct area in experimental myocardial infarct].
The model of experimental myocardial infarction in rats was used to study the effect of procedures of transcardiac galvanization (the current power 4 mA, duration 60 min) on the condition of the peri-infarction zone microcirculatory bed. The morphometric studies of the microcirculatory bed were performed using PAS reaction with amylase using a net with equidistant points. Two runs of transcardiac galvanization by the end of the first 24 hours of myocardial infarction was shown to improve the condition of the capillary network, to increase the relative and absolute area of the capillaries, the number of opened reserve capillaries, to reduce the distance of oxygen and metabolites diffusion from capillaries to cardiomyocytes in the peri-infarction zone thereby creating favourable conditions for the remaining viable myocardium and for stabilization of the affected zone.
Maslov
A G
AG
Smirnov
V P
VP
D000818:Animals; D003326:Coronary Circulation; D004195:Disease Models, Animal; D004599:Electric Stimulation Therapy; D004562:Electrocardiography; D008297:Male; D008833:Microcirculation / Q000503:physiopathology; D009203:Myocardial Infarction / Q000503:physiopathology / Q000628:therapy*; D051381:Rats; D017208:Rats, Wistar