A study from south India on the association between the papilloma virus and carcinoma of the penis.
Specimens from 39 cases of squamous cell carcinoma of the penis were treated for the papilloma virus using the bovine papilloma virus antibody and the peroxidase-antiperoxidase technique. All 39 cases showed a viral antigen situated intranuclearly, intracytoplasmically or both intranuclearly and intracytoplasmically. No correlation could be seen between the presence of viral antigen and age of patient, duration of lesion, cell morphology and histological grade. The adjacent mucosa and skin were used as controls and showed no viral antigen. The inflammatory infiltrate was dense and predominantly "T" lymphocyte in type.
Kini
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U
Department of Pathology, St. John's Medical College, Bangalore, India.
Thomas
J A
JA
Shariff
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S
D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000032:analysis; D052688:Bovine papillomavirus 1 / Q000302:isolation & purification; D002294:Carcinoma, Squamous Cell / Q000382:microbiology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007194:India; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000382:microbiology*; D014412:Tumor Virus Infections / Q000150:complications* / Q000382:microbiology
D000956:Antigens, Viral