Is the single site binding model for aldehyde dehydrogenase an oversimplification? The one-site, two-site debate revisited.
Hill
J P
JP
Department of Chemistry and Biochemistry, Massey University, Palmerston North, New Zealand.
Bennett
A F
AF
Buckley
P D
PD
Motion
R L
RL
Blackwell
L F
LF
D000444:Aldehyde Dehydrogenase / Q000737:chemistry / Q000378:metabolism*; D000447:Aldehydes; D000818:Animals; D001665:Binding Sites; D002729:Chloromercuribenzoates; D003600:Cytosol / Q000201:enzymology; D004221:Disulfiram / Q000494:pharmacology; D005453:Fluorescence; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008956:Models, Chemical; D009243:NAD / Q000378:metabolism; D011522:Protons; D012756:Sheep
D000447:Aldehydes; D002729:Chloromercuribenzoates; D011522:Protons; D009243:NAD; C005556:propionaldehyde; D000444:Aldehyde Dehydrogenase; D004221:Disulfiram