A polymorphism in the 5' region of coagulation factor VII gene (F7) caused by an inserted decanucleotide.
We describe a polymorphism in the 5' region of the coagulation factor VII (FVII) gene, originating from a decanucleotide (CCTATATCCT) insert present in the less frequent allele. This marker can be detected by restriction analysis of polymerase chain reaction products.
Centro di Studi Biochimici delle Patologie del Genoma Umano, Università di Ferrara, Italy.
G
G
Marchetti
P
P
Patracchini
M
M
Papacchini
M
M
Ferrati
F
F
Bernardi
D000483:Alleles; D001483:Base Sequence; D002882:Chromosomes, Human, Pair 13; D004247:DNA / Q000032:analysis; D004251:DNA Transposable Elements; D005167:Factor VII / Q000235:genetics*; D005787:Gene Frequency; D005799:Genes, Dominant; D006801:Humans; D008969:Molecular Sequence Data; D009841:Oligonucleotides; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic
D004251:DNA Transposable Elements; D009841:Oligonucleotides; D005167:Factor VII; D004247:DNA