Early pregnancy factor (EPF) as tumour marker in two patients with trophoblastic tumour.
Two patients with a trophoblastic tumour (one with an invasive mole and one with a choriocarcinoma) had early pregnancy factor (EPF; detected by rosette inhibition test) in serum. In both cases the EPF already disappeared during surgery which suggests that EPF could be a useful and sensitive tumour marker if laboratory technology for its detection could be improved.
Clinic of Obstetrics and Gynecology, Ernst Moritz Arndt University of Greifswald, Germany.
B
B
Bojahr
W
W
Straube
T
T
Römer
D000030:Abortion, Missed / Q000097:blood / Q000175:diagnosis; D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D018835:Chaperonin 10; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000097:blood / Q000175:diagnosis; D008875:Middle Aged; D010455:Peptides / Q000097:blood*; D011247:Pregnancy; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; D014328:Trophoblastic Neoplasms / Q000097:blood / Q000175:diagnosis*; D014594:Uterine Neoplasms / Q000097:blood / Q000175:diagnosis*
D014408:Biomarkers, Tumor; D018835:Chaperonin 10; D010455:Peptides; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; C025124:early pregnancy factor