[Liver microcirculative disturbance in schistosomiasis portal hypertension].
Using reing resin vascular casts, ink perfusion, VG and electron microscope. We studied the liver microcirculative disturbance in rabbits (n = 20) and mice (n = 10) with chronic schistosomiasis. The results showed a decrease in the liver sinusoid number, tortuosity of the terminal branches of the portal vein, formation of a basement membrane in the space of Disse, capillarization of the sinusoid. These results suggest that liver microcirculative disturbance can contribute to schistosomiasis portal hypertension.
Yang
Z
Z
Department of Basic Medicine, Tongji Hospital, Tongji Medical University.
D000818:Animals; D005260:Female; D006975:Hypertension, Portal / Q000209:etiology / Q000503:physiopathology*; D008099:Liver / Q000098:blood supply* / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008833:Microcirculation / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D012554:Schistosomiasis japonica / Q000150:complications / Q000473:pathology / Q000503:physiopathology*