[The characteristics of the action of a direct electric (galvanic) current on the ultrastructure of the normal perfused isolated heart and during its postischemic reperfusion].
The effect of direct electric current (DEC), 0.4 mA, on the ultrastructure of normal perfusing isolated heart and in the course of its postischemic reperfusion was studied on the model of isolated rat heart using Langedorf method. DEC was shown to exert a normalizing, membrane-stabilizing effect on the subcellular organization of isolated heart CMC in the course of its normothermic perfusion. The observed changes are considered to attest to the adaptive aspect of the current effect on the ultrastructure of the myocardium under these conditions. In ischemia-reperfusion, DEC also facilitated marked stabilization of cardiomyocytes membranes and stimulation of intracellular reparative processes of the affected cardiac muscle.
A G
AG
Maslov
V G
VG
Lychev
G N
GN
Maslova
D000818:Animals; D001706:Biopsy; D004560:Electricity; D006321:Heart / Q000502:physiology*; D066298:In Vitro Techniques; D008297:Male; D008854:Microscopy, Electron; D015425:Myocardial Reperfusion / Q000379:methods; D015428:Myocardial Reperfusion Injury / Q000503:physiopathology*; D009206:Myocardium / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar