[The determinants of exercise tolerance in patients with hypertensive cardiopathy].
A study was made of 45 patients with arterial hypertension, no prior angina or myocardial infarction, mean age 64 +/- 5 years, and ejection fraction > 50%. Twenty (group I) had congestive heart failure while 25 (group II) were asymptomatic. Testing following remission of symptoms revealed impaired exercise tolerance (VO2 max < 20 ml/kg/min) in 22 (subgroup A-80% from group I), and normal tolerance in 23 (subgroup B). Of ventricular function indexes, only peak filling rate correlated significantly with VO2 max (r = 0.65). Of 32 patients with thallium-201 negative in ergometric tests, the 12 in subgroup A had a higher degree of hypertrophy (p > 0.01). Nine thallium-positive patients had lower VO2 max (p > 0.05) than did 17 thallium-negative patients with a similar degree of hypertrophy. Thus, in hypertensive patients, exercise tolerance depends on prior congestive heart failure, diastolic dysfunction, degree of hypertrophy and silent regional ischemia.
Iriarte Ezkurdia
M M
MM
Instituto de Cardiología Miguel Iriarte Iriarte, Universidad del País Vasco, Bizkaia Pro-Cardíacos.
Murga Eizaga Etxebarría
N
N
Sagastagoitia Gorostiza
J D
JD
Molinero de Miguel
E
E
Ormaetxe Merodio
J
J
Morillas Bueno
M
M
Bóveda Romeo
J
J
Salcedo Arruti
A
A
D000368:Aged; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D004452:Echocardiography / Q000706:statistics & numerical data; D005080:Exercise Test / Q000706:statistics & numerical data; D017079:Exercise Tolerance; D005260:Female; D015637:Gated Blood-Pool Imaging / Q000706:statistics & numerical data; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*