Benign Leydig cell tumor of the testis associated with human papillomavirus type 33 presenting with the sign of Leser-Trélat.
We present a case of a benign testicular Leydig cell tumor and eruptive seborrheic keratosis associated with human papillomavirus type 33 infection. To our knowledge this is the first occurrence of a Leydig cell tumor in a patient with tuberous sclerosis and the second documented case of eruptive seborrheic keratoses (sign of Leser-Trélat) associated with a benign neoplasm.
Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, Maryland.
R W
RW
Martin
P
P
Rady
I
I
Arany
S K
SK
Tyring
D000328:Adult; D006801:Humans; D017403:In Situ Hybridization; D017492:Keratosis, Seborrheic / Q000382:microbiology*; D007984:Leydig Cell Tumor / Q000150:complications / Q000382:microbiology*; D008297:Male; D027383:Papillomaviridae / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D013736:Testicular Neoplasms / Q000150:complications / Q000382:microbiology*; D014402:Tuberous Sclerosis / Q000150:complications*; D014412:Tumor Virus Infections / Q000175:diagnosis*