Histones, nucleosomes and transcription.
It is becoming increasingly clear that nucleosome structure is integrally involved in gene regulation. In particular, the study of inducible genes has shown that nucleosomes not only contribute to a repressed basal state, but can also be rearranged in response to induction. The mechanism of this process is just beginning to be elucidated, and genetic studies have implicated several proteins in the modulation of nucleosome structure.
Svaren
J
J
Institut für Physiologische Chemie, Universität München, Germany.
Hörz
W
W
D000818:Animals; D002843:Chromatin / Q000648:ultrastructure; D004330:Drosophila / Q000235:genetics / Q000502:physiology; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D005786:Gene Expression Regulation; D015966:Gene Expression Regulation, Fungal; D015967:Gene Expression Regulation, Viral; D005800:Genes, Fungal; D005814:Genes, Viral; D006657:Histones / Q000235:genetics / Q000502:physiology*; D008324:Mammary Tumor Virus, Mouse / Q000235:genetics; D051379:Mice; D009707:Nucleosomes / Q000502:physiology* / Q000648:ultrastructure; D011401:Promoter Regions, Genetic; D012045:Regulatory Sequences, Nucleic Acid; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology; D014158:Transcription, Genetic
D002843:Chromatin; D005656:Fungal Proteins; D006657:Histones; D009707:Nucleosomes; D014157:Transcription Factors