[Rapid diagnosis of cytomegalovirus interstitial pneumonitis by the polymerase chain reaction method--comparison of four diagnostic procedures].
The authors conducted a comparative study on the rapid diagnosis of cytomegalovirus (CMV) interstitial pneumonitis by 4 different methods. Among them, the polymerase chain reaction (PCR) method was found to achieve the most rapid diagnosis of CMV infection. The clinical usefulness of making a diagnosis from the serum antibody titer and viral isolation was questionable as compared with the PCR method. Therefore, early diagnosis of CMV infection by PCR may be promising especially for the compromised patients with hematological diseases.
Takemoto
Y
Y
Second Department of Internal Medicine, Hyogo College of Medicine.
Hashimoto
T
T
Eizuru
Y
Y
Ogawa
A
A
Furuyama
J
J
Okada
M
M
Wada
H
H
Kanamuru
A
A
Kakishita
E
E
Nagai
K
K
D001483:Base Sequence; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000382:microbiology*; D012698:Serologic Tests