[Perioperative clinical pathomorphologic evaluation of pararectal lymph node status and its contribution to definitive decision for local excision of rectal cancer].
On the basis of 669 patients with rectal carcinoma, who underwent radical surgery, we evaluated by means of discriminant statistics the prognostic value of 7 factors concerning lymph node involvement. By stratifying for important prognostic factors (level of differentiation, lymphocytic stromal reaction, depth of tumour infiltration) we have revealed 3 different groups: I--no or rare lymph node metastases; II--more frequent metastases but confined to "N1", and III--numerous distant metastases classified as "N2-3". On the basis of these results the final decision for local extirpation of the tumour with curative intention is made easier.
Chirurgische Abteilung, Robert-Rössle-Klinik Berlin-Buch.
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W
Slisow
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C
Kolbow
J
J
Fischer
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D002288:Adenocarcinoma, Mucinous / Q000401:mortality / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003111:Colonic Polyps / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000401:mortality*; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D012007:Rectum / Q000473:pathology / Q000601:surgery; D015996:Survival Rate