[Changes in the properties of the brain opiate, DA2, GABA, and 5-HT1 receptors in the progeny of female rats consuming ethanol for a long time during pregnancy and lactation].
The study was undertaken to examine two-week and two-month rats whose mothers had been given alcohol for a long period of time during pregnancy and lactation. Profound changes were found in the properties of all types of the receptors under study. The changes were found in the receptors of both group animals. Substantial changes were encountered in the properties of GABA and DA2 receptors in the brain of two-month rats after acute alcoholization. The changes were differentiated from those seen in GABA and DA2 receptors in the brain of the rats whose mothers had not been given ethanol.
Vekshina
N L
NL
Khristoliubova
N A
NA
D000375:Aging / Q000187:drug effects; D000428:Alcohol Drinking / Q000009:adverse effects*; D000818:Animals; D001921:Brain / Q000187:drug effects*; D001923:Brain Chemistry / Q000187:drug effects; D005260:Female; D007774:Lactation / Q000187:drug effects*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D011956:Receptors, Cell Surface / Q000032:analysis / Q000187:drug effects*; D017448:Receptors, Dopamine D2 / Q000032:analysis / Q000187:drug effects; D011963:Receptors, GABA-A / Q000032:analysis / Q000187:drug effects; D011957:Receptors, Opioid / Q000032:analysis / Q000187:drug effects; D011985:Receptors, Serotonin / Q000032:analysis / Q000187:drug effects
D011956:Receptors, Cell Surface; D017448:Receptors, Dopamine D2; D011963:Receptors, GABA-A; D011957:Receptors, Opioid; D011985:Receptors, Serotonin