AccuMeter noninstrumented quantitative assay of high-density lipoprotein in whole blood.
A novel noninstrumented technology (ChemTrak AccuMeter) for the quantitative measurement of analytes in biological fluids was reported at the 1990 Oak Ridge Conference (Clin Chem 1990;36:1591-7). This instrument-free technology has been adapted for the quantitative measurement of high-density lipoprotein (HDL). An in situ lipoprotein separation method has been developed and incorporated into the test for HDL determination. The sensitivity of the assay system has been adjusted so that HDL is measured over a clinically significant range of 250 to 1000 mg/L. This compares to a range of 1000 to 4000 mg/L for the total cholesterol in the earlier reported assay. Like the AccuMeter total cholesterol test, the Accumeter HDL test system is self-contained and consolidates blood separation, lipoprotein separation, and specimen measurement into a single step. The test procedure is simple, and the results are accurate.
Liu
V Y
VY
ChemTrak, Inc., Sunnyvale, CA 94086-4520.
Lin
T Y
TY
Schrier
W
W
Allen
M
M
Singh
P
P
D001774:Blood Chemical Analysis / Q000295:instrumentation; D002854:Chromatography, Paper; D006801:Humans; D007122:Immunoelectrophoresis; D008075:Lipoproteins, HDL / Q000097:blood*; D012680:Sensitivity and Specificity
D008075:Lipoproteins, HDL