Primary ovarian small cell carcinoma: four more cases.
A case report of four patients affected by primary ovarian small cell carcinoma is presented. The surgical and chemotherapeutic approaches are described for each case. Cisplatin-based chemotherapy obtained objective responses in two of four patients, but three of four patients died of disease progression within 2 years from the diagnosis. One patient, who was stage Ib and underwent bilateral salpingo-oophorectomy, total hysterectomy, and adjuvant chemotherapy is still alive 58 months after surgery. Accurate diagnosis and a multidisciplinary approach are needed to ameliorate the prognosis of this tumor that, at present, remains very poor.
Peccatori
F
F
Department of Obstetrics and Gynecology, Ospedale San Gerardo, Istituto di Scienze Biomediche San Gerardo, University of Milan, Monza, Italy.
Bonazzi
C
C
Lucchini
V
V
Bratina
G
G
Mangioni
C
C
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology / Q000628:therapy*; D010052:Ovariectomy