[The development of chronic kidney failure in spontaneously hypertensive rats].
Normotensive Wistar and spontaneously hypertensiverten Okamoto rats with relatively low blood pressure were compared with regard to the development of chronic renal failure after subtotal renal ablation. Structural and biochemical studies revealed that Okamoto rats had more intensive glomerular sclerosis and higher degrees of chronic renal failure than Wistar rats.
V V
VV
Barabanova
V A
VA
Titova
E L
EL
Miroshnichenko
T E
TE
Timoshenko
D000818:Animals; D001794:Blood Pressure; D004195:Disease Models, Animal; D007668:Kidney / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D009392:Nephrectomy; D051381:Rats; D011918:Rats, Inbred SHR / Q000502:physiology*; D017208:Rats, Wistar; D013997:Time Factors