Tc-99m HM-PAO pulmonary imaging of large cell carcinoma in the lung of a smoker showing a rounded photon deficient area.
Tc-99m HM-PAO has been used as a tumor-imaging agent because this radiopharmaceutical localizes in tumor masses, including lung carcinoma. We present a smoker with giant-cell-carcinoma of the lung whose Tc-99m MAA and Tc-99m HM-PAO lung images showed a photon-deficient area corresponding to the tumor mass. Rapid growth of large cell carcinoma leading to tumor necrosis and interruption of blood flow resulted in a localized photon deficient area in diffuse lung uptake secondary to a long smoking history on a Tc-99m HM-PAO lung images.
Nuclear Medicine Service, Department of Veterans Affairs Medical Center, Lexington, KY 40511.
W J
WJ
Shih
M L
ML
Dillon
D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010091:Oximes; D011877:Radionuclide Imaging; D012907:Smoking / Q000009:adverse effects*; D013668:Technetium Tc 99m Aggregated Albumin; D019690:Technetium Tc 99m Exametazime; D013997:Time Factors
D015609:Organotechnetium Compounds; D010091:Oximes; D013668:Technetium Tc 99m Aggregated Albumin; D019690:Technetium Tc 99m Exametazime