Imperforate hymen: report of an unusual familial occurrence.
BACKGROUND
Although imperforate hymen occurs in approximately 0.1% of female newborns, familial occurrence of imperforate hymen has been reported only once.


METHODS
We report two families in which imperforate hymen was diagnosed in three siblings of each family. One family is described in detail; the patients were two postmenarchal young women and one premenarchal girl.


CONCLUSIONS
Imperforate hymen usually occurs sporadically but can be familial. We advise screening all female newborns and children for vaginal patency, especially family members of an affected child. Identification of other families with a similar problem might point to a specific mode of inheritance.
Usta
I M
IM
Department of Obstetrics and Gynecology, American University of Beirut-Medical Center, Lebanon.
Awwad
J T
JT
Usta
J A
JA
Makarem
M M
MM
Karam
K S
KS
D000293:Adolescent; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D006801:Humans; D006924:Hymen / Q000002:abnormalities*