Volume-dependent potassium transport in camel red blood cells.
In this study the volume-dependent, ouabain-resistant K+ influx and efflux in camel red blood cells were measured with the tracer 86Rb+. The results showed that the camel erythrocytes do not have the Na(+)-K+ cotransport. The cell swelling increases a ouabain-resistant K+ influx and shrinkage decreases it nearly two-fold. The swelling-stimulated K+ influx and efflux were chloride dependent. The anion dependence of K+ influx in swollen cells was as follows: Br- > Cl- > NO3. The pH-dependent curve for swelling-stimulated potassium influx, and the active K+ influx in camel erythrocytes were determined. The findings indicate that camel erythrocytes' potassium transport system has many similarities to other mammalian species.
Department of Physiology and Biochemistry, Jordan University of Science and Technology, Irbid.
N S
NS
Gharaibeh
N M
NM
Rawashdeh
D000818:Animals; D000838:Anions / Q000494:pharmacology; D001692:Biological Transport; D002162:Camelus / Q000097:blood*; D002352:Carrier Proteins / Q000097:blood; D004912:Erythrocytes / Q000166:cytology* / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D009994:Osmolar Concentration; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium / Q000097:blood* / Q000493:pharmacokinetics; D028021:Sodium-Potassium-Chloride Symporters; D000254:Sodium-Potassium-Exchanging ATPase / Q000502:physiology
D000838:Anions; D002352:Carrier Proteins; D028021:Sodium-Potassium-Chloride Symporters; D010042:Ouabain; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium