Bladder sparing surgery for locally advanced female urethral cancer.
Cystectomy remains one of the standard treatments for women with locally advanced (stage C) urethral cancer, or stage A or B lesions that have failed radiation therapy. Often, the urethral neoplasm does not invade the bladder. We treated 5 women with stage C urethral cancer by wide local excision with or without concomitant radiation therapy, while preserving the bladder. Local control was achieved in all patients with followup ranging from 4 to 75 months (median 42). We believe that bladder sparing treatment strategies should be considered for selected stage C tumors when the bladder is not invaded by the neoplasm.
Hedden
R J
RJ
Department of Surgery, University of Cincinnati Medical Center, Ohio.
Husseinzadeh
N
N
Bracken
R B
RB
D000230:Adenocarcinoma / Q000532:radiotherapy / Q000601:surgery*; D000368:Aged; D001918:Brachytherapy; D002295:Carcinoma, Transitional Cell / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D014521:Urethra / Q000601:surgery*; D014523:Urethral Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D001743:Urinary Bladder