Direct interaction of the sialic acid residue of human lutropin and chorionic gonadotropin with target cell is necessary for the full expression of their hormonal action.
Amano
J
J
Department of Biochemistry, University of Tokyo, Japan.
Kobata
A
A
D001665:Binding Sites; D006063:Chorionic Gonadotropin / Q000737:chemistry*; D000242:Cyclic AMP / Q000096:biosynthesis; D006801:Humans; D007986:Luteinizing Hormone / Q000737:chemistry*; D011134:Polysaccharides / Q000494:pharmacology; D011974:Receptors, LH / Q000737:chemistry* / Q000378:metabolism; D012794:Sialic Acids / Q000737:chemistry*; D013329:Structure-Activity Relationship
D006063:Chorionic Gonadotropin; D011134:Polysaccharides; D011974:Receptors, LH; D012794:Sialic Acids; D007986:Luteinizing Hormone; C014420:colominic acid; D000242:Cyclic AMP