Thallium-201 technetium-99m HMPAO single-photon emission computed tomography (SPECT) imaging for guiding stereotactic craniotomies in heavily irradiated malignant glioma patients.
SPECT scanning with Tl-201 and Tc-99m offers a unique, inexpensive functional imaging modality to combine with CT stereotactic craniotomy for guiding resection of necrosis and/or tumour in patients treated with escalated doses of radiation (> 6000 cGy) by either brachytherapy or radiosurgery. Thirty-two cases were analyzed, with a detailed description of the imaging and operative techniques.
Alexander
E
E
Department of Surgery (Neurosurgery), Harvard Medical School, Brigham and Women's Hospital, Boston, Massechusetts.
Loeffler
J S
JS
Schwartz
R B
RB
Johnson
K A
KA
Carvalho
P A
PA
Garada
B M
BM
Zimmerman
R E
RE
Holman
B L
BL
D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D001918:Brachytherapy; D001921:Brain / Q000473:pathology / Q000528:radiation effects*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D003399:Craniotomy; D005500:Follow-Up Studies; D005910:Glioma / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009336:Necrosis; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery; D015609:Organotechnetium Compounds; D010091:Oximes; D011832:Radiation Injuries / Q000000981:diagnostic imaging* / Q000601:surgery; D016634:Radiosurgery; D011879:Radiotherapy Dosage; D012086:Reoperation; D012984:Software; D013238:Stereotaxic Techniques; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime