[Ganglioside GM3 from horse erythrocytes: structure and effect on cell proliferation].
An increase of the mouse fibroblast proliferation by ganglioside GM3 from equine erythrocytes is described. The structure of GM3 has been established on the basis of chemical methods, enzymatic degradation, GC-MS, as well as plasma desorption mass spectrometry and HPLC of 9-anthrylmethyl esters of gangliosides to characterize the long-chain base composition. The oligosaccharide moiety includes an N-glycolylneuraminic acid residue, whereas the main components of the lipid moiety are 20:1 sphingosine and 24:0 fatty acids.
Menzeleev
R F
RF
Smirnova
G P
GP
Chekareva
N V
NV
Zvonkova
E N
EN
Krasnopol'skiĭ
Iu M
IuM
Shvets
V I
VI
D000818:Animals; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D004912:Erythrocytes / Q000187:drug effects*; D005679:G(M3) Ganglioside / Q000737:chemistry* / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D006736:Horses; D008969:Molecular Sequence Data
D005679:G(M3) Ganglioside