[Epidermal cysts and folliculitis caused by cyclosporin A].
A 66-year-old man was treated with cyclosporin A (Sandimmun) after a kidney transplant and developed numerous epidermal cysts, comedones and folliculitis in the 2nd year of the immunosuppressive therapy. The eruptions were more marked on the back and in the temporal and retroauricular regions of the face. Histological examination of a cystic tumour revealed a follicular cyst of the acro-infundibular type. While hypertrichosis and gingival hyperplasia are now well known as side effects of cyclosporin A, cystic and acneiform skin lesions must also be attributed to this drug.
Hautklinik der Städtischen Kliniken Dortmund.
A
A
Richter
S
S
Beideck
W
W
Bender
P J
PJ
Frosch
D000152:Acne Vulgaris / Q000139:chemically induced / Q000473:pathology; D000368:Aged; D001706:Biopsy; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects*; D004814:Epidermal Cyst / Q000139:chemically induced* / Q000473:pathology; D005499:Folliculitis / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications / Q000139:chemically induced* / Q000473:pathology; D012867:Skin / Q000473:pathology
D016572:Cyclosporine