[DNA as a prognostic factor in colorectal cancer. A retrospective analysis of 34 patients].
OBJECTIVE
We study the tumoral DNA as a prognostic factor in patients operated for colo-rectal cancer.


METHODS
Retrospective. We analyze by flow cytometry the DNA content of tumoral tissue: Ploidy, DNA Index, Proliferative Index, S Phase.


METHODS
34 operated patients, for colo-rectal cancer, with a minimum 3 years of follow-up.


RESULTS
Ploidy doesn't show any relation with other prognostic factors. Only Dukes C aneuploid patients had more positive nodes than diploid. Ploidy was not related to better evolution or survival. Neither DNA Index, Proliferative Index and S Phase were related to the evolution of the disease.


CONCLUSIONS
The DNA study by flow cytometry has no better prognostic value then other classical factors.
Bianchi
A
A
Servicio Cirugía General, Consorci Sanitari de Mataró, Hospital Sant Jaume i Sta. Magdalena.
Mallofre
C
C
Serrano
A
A
Suñol
J
J
Barja
J
J
Ubach
M
M
D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000737:chemistry / Q000235:genetics*; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D011379:Prognosis; D012189:Retrospective Studies
D004273:DNA, Neoplasm