Intracavernosal papaverine and phentolamine for the medical management of erectile dysfunction in a genitourinary clinic.
A total of 160 men with erectile failure received treatment with 13,030 intracavernosal papaverine and phentolamine injections as outpatients. One-hundred-and-fifteen (72%) achieved an erection sufficient for sexual intercourse and after a mean follow-up period of 14.1 months, 55 (48%) are still attending and successfully using intracavernous therapy. Sixteen patients had a total of 22 episodes of priapism and one patient developed corporeal fibrosis. We conclude that intracavernous papaverine and phentolamine is an effective therapy for erectile failure in a genitourinary clinic.
Department of Genitourinary Medicine, Royal Victoria Hospital, Belfast, Northern Ireland.
D K
DK
Armstrong
A
A
Convery
W W
WW
Dinsmore
D000328:Adult; D000368:Aged; D003075:Coitus / Q000502:physiology; D003151:Community Health Centers; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009660:Northern Ireland; D010208:Papaverine / Q000008:administration & dosage* / Q000009:adverse effects; D010409:Penile Diseases / Q000188:drug therapy; D010410:Penile Erection / Q000187:drug effects*; D010646:Phentolamine / Q000494:pharmacology / Q000627:therapeutic use*
D010208:Papaverine; D010646:Phentolamine