Abnormal degradation of red cell membrane proteins in diabetes.
The degradation of main membrane proteins, spectrin and band 3 protein, was studied in erythrocyte membranes of elderly diabetic patients and of healthy donors of various ages. In general, the rates of proteolysis were higher in diabetics. The degradation intensity depended on the sex of the diabetic patients and on the age of healthy donors.
Department of Biophysics, University of Lódź, Poland.
M
M
Gaczyńska
L
L
Judkiewicz
K
K
Szosland
D000293:Adolescent; D000328:Adult; D001457:Anion Exchange Protein 1, Erythrocyte / Q000032:analysis; D003920:Diabetes Mellitus / Q000097:blood*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000097:blood*; D008875:Middle Aged; D012737:Sex Factors; D013049:Spectrin / Q000032:analysis
D001457:Anion Exchange Protein 1, Erythrocyte; D008565:Membrane Proteins; D013049:Spectrin