Factors influencing anaemia in dialysis patients. A special survey by the EDTA-ERA Registry.
The European Dialysis and Transplantation Association-European Renal Association (EDTA-ERA) Registry conducted a special study on anaemia in dialysis patients because it seemed important to elucidate the various factors that influence the degree of anaemia and the use of regular transfusions in dialysis patients before the introduction of recombinant human erythropoietin (rHuEpo) for larger groups of patients. In a 20% sample of all patients recorded to have been dialysed throughout 1987, statistically significant associations could be found by multifactorial analysis between haemoglobin (Hb) concentration and age, sex, primary renal disease, type of treatment, hours of dialysis per week, and number of years on renal replacement therapy. The type of dialyser membrane did not seem to play a role (although there was weak evidence of an effect of the dialyser). Mean Hb concentration for dialysis patients differed between countries as did the transfusion policy. In view of the high costs of the rHuEpo treatment and potential side-effects, factors such as method of dialysis and hours of haemodialysis per week should be taken into consideration in the treatment of anaemia in dialysis patients.
Leyenberg Ziekenhuis, The Hague, Netherlands.
W
W
Geerlings
R W
RW
Morris
F P
FP
Brunner
H
H
Brynger
J H
JH
Ehrich
W
W
Fassbinder
G
G
Rizzoni
N H
NH
Selwood
G
G
Tufveson
A J
AJ
Wing
D000293:Adolescent; D000328:Adult; D000368:Aged; D000740:Anemia / Q000209:etiology* / Q000628:therapy; D001803:Blood Transfusion; D002648:Child; D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory; D012042:Registries; D006435:Renal Dialysis / Q000009:adverse effects
D006454:Hemoglobins; D004921:Erythropoietin