Atheroemboli-associated polyps of the sigmoid colon.
Atheroemboli-associated inflammatory type polyps localized to a portion of the sigmoid colon occurred in a 68-year-old diabetic man presenting with a 2-year history of bloody diarrhea and abdominal pain. The patient underwent segmental resection of the sigmoid colon. The specimen contained 15 polyps ranging from 0.3 to 1.9 cm in greatest dimension, localized to an 8-cm length of sigmoid colon. The polyps had an edematous submucosa with a superficially ulcerated mucosa. Microscopically, arterioles within the submucosa of the polyps contained organized atheroemboli. The overlying mucosa was largely replaced by granulation tissue, with foci of coagulation necrosis present in residual mucosa. The remainder of the bowel was unremarkable. The histologic diagnosis of atheroembolization to the gastrointestinal tract is difficult, requiring the inclusion of submucosa with atheroemboli in the biopsy tissue. Ischemic ulcers and erosions as well as inflammatory polyps related to atheroemboli may require deeper biopsy for etiologic diagnosis.
Cheville
J C
JC
Department of Pathology, University of Iowa College of Medicine, Iowa City 52242.
Mitros
F A
FA
Vanderzalm
G
G
Platz
C E
CE
D000368:Aged; D003111:Colonic Polyps / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D004620:Embolism, Fat / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D012811:Sigmoid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery