A mathematical model for fundamental regulation processes in the cardiovascular system.
Based on the four compartment model by Grodins we develop a model for the response of the cardiovascular system to a short term submaximal workload. Basic mechanisms included in the model are Starling's law of the heart, the Bowditch effect and autoregulation in the peripheral regions. A fundamental assumption is that the action of the feedback control is represented by the baroceptor loop and minimizes a quadratic cost functional. Simulation results show that the model provides a satisfactory description of data obtained in bicycle ergometer tests.
Institut für Mathematik, Universität Graz, Austria.
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D001794:Blood Pressure / Q000502:physiology; D001810:Blood Volume / Q000502:physiology; D002320:Cardiovascular Physiological Phenomena; D003198:Computer Simulation; D005246:Feedback; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008433:Mathematics; D008955:Models, Cardiovascular; D011311:Pressoreceptors / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology; D016276:Ventricular Function