[The interrelationship of the content of catecholamines in salivary gland tissue, oral mucosa and in the saliva in experimental staphylococcal sialoadenitis].
Catecholamine contents in non-stimulated and pilocarpine-stimulated submaxillary salivary gland tissue (SGT), oral mucosa (OM) and stimulated saliva in acute experimental staphylococcal sialoadenitis were determined in rats using standard HPLC method. It was shown that 2 hrs after toxin injection, NA contents decreased in non-stimulated SGT, NA and A contents in SGT and OM also decreased. After 2 and 24 hrs NA and A contents were not changed in stimulated SGT and OM and after 24 hrs A content increased in SGT and OM. In saliva after 2 hrs the content and secretion of NA increased, after 24 hrs the content and secretion of NA decreased, but that of A increased. It was concluded that in sialoadenitis the disorders of catecholamine contents in the saliva correlated with its content in OM and influenced the trophic of OM and could be conductive to the development of its pathology.
Mikhaĭlov
V V
VV
Rusanova
A G
AG
D000208:Acute Disease; D000818:Animals; D002395:Catecholamines / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D005260:Female; D008297:Male; D009061:Mouth Mucosa / Q000737:chemistry* / Q000187:drug effects; D010862:Pilocarpine / Q000494:pharmacology; D051381:Rats; D012463:Saliva / Q000737:chemistry* / Q000187:drug effects; D012469:Salivary Glands / Q000737:chemistry* / Q000187:drug effects; D012472:Salivation / Q000187:drug effects; D012793:Sialadenitis / Q000378:metabolism*; D013203:Staphylococcal Infections / Q000378:metabolism*
D002395:Catecholamines; D010862:Pilocarpine