Cytomegalovirus retinitis in pediatric acquired immunodeficiency syndrome: report of two cases.
Two cases of cytomegalovirus retinitis in pediatric acquired immunodeficiency syndrome (AIDS) are described. The first case was a 7-month-old infant who received an HIV-infected blood transfusion in 1983. The infant was treated with specific anti-cytomegalovirus immunoglobulin. The second case was an 8-year-old hemophiliac child who received HIV-infected factor VIII concentrates. Intravenous ganciclovir therapy resulted in marked improvement of ocular lesions. This is, to our best knowledge, the first report of pediatric AIDS-induced retinopathy resulting from postnatal intravenous causes.
Section of Pediatric Ophthalmology, Hospital Materno-Infantil del Vall d'Hebron, Barcelona, Spain.
F
F
Salvador
R
R
Blanco
A
A
Colín
A
A
Galán
J J
JJ
Gil-Gibernau
D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000163:Acquired Immunodeficiency Syndrome / Q000209:etiology; D002648:Child; D003586:Cytomegalovirus Infections / Q000209:etiology*; D015828:Eye Infections, Viral / Q000209:etiology*; D005169:Factor VIII / Q000009:adverse effects; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D012173:Retinitis / Q000382:microbiology*; D065227:Transfusion Reaction
D005169:Factor VIII; D015774:Ganciclovir