Primary ovarian small cell carcinoma: four more cases.
A case report of four patients affected by primary ovarian small cell carcinoma is presented. The surgical and chemotherapeutic approaches are described for each case. Cisplatin-based chemotherapy obtained objective responses in two of four patients, but three of four patients died of disease progression within 2 years from the diagnosis. One patient, who was stage Ib and underwent bilateral salpingo-oophorectomy, total hysterectomy, and adjuvant chemotherapy is still alive 58 months after surgery. Accurate diagnosis and a multidisciplinary approach are needed to ameliorate the prognosis of this tumor that, at present, remains very poor.
Department of Obstetrics and Gynecology, Ospedale San Gerardo, Istituto di Scienze Biomediche San Gerardo, University of Milan, Monza, Italy.
F
F
Peccatori
C
C
Bonazzi
V
V
Lucchini
G
G
Bratina
C
C
Mangioni
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology / Q000628:therapy*; D010052:Ovariectomy