Cytomegalovirus infections of the oral cavity. A report of six cases and review of the literature.
Cytomegalovirus is responsible for a significant percentage of asymptomatic viral infections worldwide. Although virtually any cell or organ may be infected, involvement of the oral cavity is uncommon. Only nine well-documented examples of intraoral cytomegalovirus infections were found in a review of the English-language literature. We report six additional examples, five of which possessed unique clinical and histopathologic characteristics. The light and electron-microscopic features of cytomegalovirus are discussed, as well as diagnostic adjuncts such as immunohistochemistry and deoxyribonucleic acid in situ hybridization.
Jones
A C
AC
Department of Oral Diagnostic Sciences, University of Florida College of Dentistry, Gainesville.
Freedman
P D
PD
Phelan
J A
JA
Baughman
R A
RA
Kerpel
S M
SM
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D000368:Aged; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D004279:DNA, Viral / Q000032:analysis; D006679:HIV Seropositivity / Q000150:complications; D006660:Histoplasmosis / Q000150:complications; D006801:Humans; D017403:In Situ Hybridization; D007181:Inclusion Bodies, Viral; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D012514:Sarcoma, Kaposi / Q000150:complications; D013283:Stomatitis, Herpetic / Q000150:complications
D004279:DNA, Viral