The newly discovered retinoic acid-X receptors (RXRs).
All-trans-retinoic acid functions by binding to nuclear receptor proteins (RAR alpha,beta,gamma) that interact with response elements in various genes involved in development and differentiation. A new family of nuclear receptors (RXR alpha,beta,gamma) has been discovered that uses 9-cis-retinoic acid as ligand and may function particularly in regulation of genes involved in intermediary metabolism.
Department of Nutritional Sciences, University of California, Berkeley 94720.
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D002352:Carrier Proteins / Q000502:physiology*; D006801:Humans; D009928:Organ Specificity; D018168:Receptors, Retinoic Acid; D012177:Retinol-Binding Proteins / Q000235:genetics / Q000378:metabolism; D054840:Retinol-Binding Proteins, Cellular; D014212:Tretinoin / Q000378:metabolism
D002352:Carrier Proteins; C518459:RBP2 protein, human; D018168:Receptors, Retinoic Acid; D012177:Retinol-Binding Proteins; D054840:Retinol-Binding Proteins, Cellular; D014212:Tretinoin