A retrospective study of 370 borderline tumors of the ovary treated at the Norwegian Radium Hospital from 1970 to 1982. A review of clinicopathologic features and treatment modalities.
METHODS
Three-hundred seventy patients with borderline tumors treated between 1970 and 1982 at the Norwegian Radium Hospital were analyzed retrospectively for clinicopathologic features, treatment, and survival characteristics.


RESULTS
One hundred seventy-eight patients had mucinous tumors, 174 patients had serous tumors, and 18 patients had other types of tumors. There were 311 patients with Stage I, 20 with Stage II, and 39 with Stage III tumors by the classification of the International Federation of Gynecology and Obstetrics. Most of the patients were treated in conformity with the protocols for invasive carcinoma at the current time. Total abdominal hysterectomy, bilateral adnexectomy, and omentectomy were performed in 287 patients and less extensive surgery was performed in 77 patients. Only six patients had residual tumor after surgery. The independent prognostic factors evaluated by Cox analysis in regard to corrected (dead of disease) short-term and long-term survival were stage (P < 0.0001) and histologic type (P = 0.0144); age (P = 0.0115) affected only long-term survival. Adjuvant treatment was of no benefit.


CONCLUSIONS
Stage, histologic type, and age had prognostic significance. Fertility-saving surgery can be offered to patients with Stage IA disease with serous or mucinous tumors.
Department of Gynecologic Oncology, Norwegian Radium Hospital, Montebello, Oslo.
J
J
Kaern
C G
CG
Tropé
V M
VM
Abeler
D002288:Adenocarcinoma, Mucinous / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D015996:Survival Rate