Ascaridole as a pharmacologically active principle of "Paico," a medicinal Peruvian plant.
"Paico," Chenopodium ambrosioides L., is a traditional Peruvian medicine which is considered to be nervine, antirheumatic, anthelmintic, etc. An attempt was made to isolate the component having sedative and/or analgesic properties from "Paico" and "Aritasou" (the Japanese name for C. ambrosioides). Ascaridole was identified as the active principle in both materials.
Okuyama
E
E
Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Umeyama
K
K
Saito
Y
Y
Yamazaki
M
M
Satake
M
M
D000700:Analgesics / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D000871:Anthelmintics / Q000302:isolation & purification* / Q000494:pharmacology; D000081005:Cyclohexane Monoterpenes; D006993:Hypnotics and Sedatives / Q000302:isolation & purification* / Q000494:pharmacology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D039821:Monoterpenes; D010545:Peroxides; D010568:Peru; D010946:Plants, Medicinal / Q000737:chemistry*; D013729:Terpenes / Q000302:isolation & purification* / Q000494:pharmacology
D000700:Analgesics; D000871:Anthelmintics; D000081005:Cyclohexane Monoterpenes; D006993:Hypnotics and Sedatives; D039821:Monoterpenes; D010545:Peroxides; D013729:Terpenes; C043372:ascaridole