[Lysis block technique. Local fibrinolytic treatment of venous and arterial occlusions].
With lysis-block technique an oversystolic tourniquet is put on the thigh or upper arm. The fibrinolytic substance is injected into a dorsal foot vein or forearm vein. By using this strictly local lysis it was possible to remove distal venous and arterial occlusions. During oversystolic blockade there was only a minimal link between the blocked part of the limb and systemic circulation. By choosing a lytic substance with a short half-life-period (rt-PA) the systemic effect after loosening the blockade was small. LBT is a new and interesting method for the fibrinolytic treatment of peripheral venous and arterial occlusions. The procedure is characterized by minimal systemic reactions and it can probably be applied in those patients with contraindications for systemic lysis.
Heimig
T
T
Geriatrischen Klinik, Städtischen Kliniken Duisburg, Deutschland.
Martin
M
M
D000765:Anesthesia, Conduction; D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000628:therapy*; D001162:Arteriosclerosis Obliterans / Q000628:therapy; D010478:Chemotherapy, Cancer, Regional Perfusion; D006801:Humans; D007866:Leg / Q000098:blood supply*; D012039:Regional Blood Flow / Q000187:drug effects; D015912:Thrombolytic Therapy; D013924:Thrombophlebitis / Q000628:therapy*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage* / Q000009:adverse effects
D010959:Tissue Plasminogen Activator