Plasma and red blood cell magnesium levels and plasma creatinine after a 100 km race.
Magnesium homeostasis is critical for exercise performance. In this report the effect of long distance race on the erythrocyte and plasma magnesium concentration is determined in a group of 7 well-trained male amateur runners. After a 100 km race the plasma Mg2+ levels increased significantly from 0.845 +/- 0.074 to 0.934 +/- 0.099 mmol.l-1 (p < 0.05). However, the intra-erythrocyte Mg2+ concentrations were not modified significantly (2.10 +/- 0.2 mmol.l-1 versus 2.14 +/- 0.12 mmol.l-1). Creatinine plasma levels increased significantly from 73.4 +/- 3.5 mumol.l-1 to 117.6 +/- 19.4 mumol.l-1 (p < 0.01), suggesting impairment of the renal function. A significant positive correlation between plasma magnesium and plasma creatinine, r = +0.65 (p < 0.01) was found. These results suggest that an increase in the magnesium plasma levels could be related to renal failure during long-distance running.
Rama
R
R
Departamento de Bioquímica y Fisiología, Facultad de Biología, Universidad de Barcelona, Spain.
Ibáñez
J
J
Pagés
T
T
Callis
A
A
Palacios
L
L
D000328:Adult; D003402:Creatine Kinase / Q000097:blood; D003404:Creatinine / Q000097:blood*; D004912:Erythrocytes / Q000737:chemistry*; D006400:Hematocrit; D006706:Homeostasis; D006801:Humans; D007527:Isoenzymes; D007668:Kidney / Q000502:physiology*; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008274:Magnesium / Q000032:analysis* / Q000097:blood; D008297:Male; D012420:Running / Q000502:physiology*
D007527:Isoenzymes; D007773:Lactates; D019344:Lactic Acid; D003404:Creatinine; D003402:Creatine Kinase; D008274:Magnesium