Experimental infection of weaned calves and lambs with two strains of bovine adenovirus type 2.
The pathogenicity of two genetically different strains of bovine adenovirus type 2 (BAV-2) was tested in a double cross experimental infection of weaned lambs and calves. One of the virus strains was isolated from cattle and represented BAV-2 subgroup "A", while the other was isolated from sheep and belonged to subgroup "B" (Belák et al., 1983). The two virus strains caused infection both in lambs and calves; the viruses were repeatedly reisolated and definite seroconversion was found in all four groups. However, remarkable differences were observed in the pathogenicity: the most intensive virus multiplication and shedding, the most severe clinical symptoms and histopathological lesions were observed in the lamb group infected with the ovine isolate.
Department of Microbiology and Infectious Diseases, University of Veterinary Science, Budapest, Hungary.
M
M
Rusvai
R
R
Glávits
L
L
Kucsera
S
S
Belák
D000256:Adenoviridae / Q000472:pathogenicity*; D000257:Adenoviridae Infections / Q000382:microbiology / Q000662:veterinary*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D005260:Female; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology*