Characterization of Centers for Disease Control group NO-1, a fastidious, nonoxidative, gram-negative organism associated with dog and cat bites.
Seventeen strains of fastidious, nonoxidative, gram-negative rods, isolated from human wounds resulting primarily from dog or cat bites, formed a distinct group, which was designated Centers for Disease Control (CDC) group nonoxidizer 1 (NO-1). The phenotypic characteristics of CDC group NO-1 were most similar to non-acid-producing Acinetobacter species, with the major difference being a negative reaction in the transformation assay test for Acinetobacter spp. The cellular fatty acid composition of CDC group NO-1 was different from those of Acinetobacter species and all other bacteria tested to date. The isolates were susceptible to a variety of antimicrobial agents including the aminoglycosides, beta-lactam antibiotics, tetracyclines, quinolones, and sulfonamides. Fifty percent of the isolates were resistant to trimethoprim. Ubiquinone-8 was present as the major isoprenoid quinone in CDC group NO-1.
Special Bacteriology Reference Laboratory, Centers for Disease Control and Prevention, Atlanta, Georgia 30333.
D G
DG
Hollis
C W
CW
Moss
M I
MI
Daneshvar
L
L
Meadows
J
J
Jordan
B
B
Hill
D000150:Acinetobacter / Q000145:classification; D000818:Animals; D015373:Bacterial Typing Techniques; D001733:Bites and Stings / Q000382:microbiology*; D002415:Cats; D002487:Centers for Disease Control and Prevention, U.S. / Q000592:standards; D004285:Dogs; D005227:Fatty Acids / Q000032:analysis; D006088:Gram-Negative Aerobic Bacteria / Q000145:classification*; D006801:Humans; D008826:Microbial Sensitivity Tests; D014481:United States; D014946:Wound Infection
D005227:Fatty Acids