Human connexin43 gene locus, GJA1, sublocalized to band 6q21-->q23.2.
Gap junctions permit transfer of small molecules directly between cells. Several laboratories have mapped the human gap junction protein subunit, connexin43 (locus designation, GJA1), to overlapping regions of chromosome 6, localizing GJA1 to 6q14-->q24. We have sublocalized human GJA1 to a very small region. 6q21-->q23.2, using a human x rodent somatic cell hybrid mapping panel and a rat connexin43 cDNA probe.
Corcos
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Department of Biology, University of Michigan, Ann Arbor.
Meese
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Loch-Caruso
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D015139:Blotting, Southern; D002874:Chromosome Mapping; D002896:Chromosomes, Human, Pair 6; D017630:Connexins; D006801:Humans; D006822:Hybrid Cells; D008565:Membrane Proteins / Q000235:genetics*
D017630:Connexins; D008565:Membrane Proteins