Metoclopramide in anorexia caused by cancer-associated dyspepsia syndrome (CADS).
Anorexia is a common problem in advanced cancer, part of the cancer anorexia-cachexia syndrome. Although the etiology is multifactorial, symptoms suggestive of gastroparesis are often present in patients with cancer anorexia. We have successfully used metoclopramide, a prokinetic agent, to stimulate appetite in advanced cancer and relieve other dyspeptic symptoms associated with anorexia.
Department of Hematology/Oncology, Cleveland Clinic Cancer Center, Ohio.
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Nelson
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Walsh
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000855:Anorexia / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004415:Dyspepsia / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000503:physiopathology*; D013577:Syndrome
D008787:Metoclopramide