Systemic cytomegalovirus infection mimicking an exacerbation of Wegener's granulomatosis.
A patient with Wegener's granulomatosis developed a systemic cytomegalovirus infection that mimicked an exacerbation of her vasculitis including pulmonary infiltrates, renal insufficiency, and cutaneous necrotizing ulcers. All of her symptoms resolved with ganciclovir. Physicians should maintain a high index of suspicion for similar presentations in other patients with vasculitis with or without immunosuppressive therapy.
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor.
D J
DJ
Weiss
J W
JW
Greenfield
K S
KS
O'Rourke
W J
WJ
McCune
D000368:Aged; D003520:Cyclophosphamide / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D013902:Radiography, Thoracic
D003520:Cyclophosphamide; D015774:Ganciclovir; D011241:Prednisone