[The thermoregulatory response to noradrenaline in rats tested for stress or pharmacological exposures in the early postnatal period].
Norepinephrine-induced increase of the thermoconductivity of the body surface was depressed in rats exposed to cold, handling or treatment with thyroid hormone or alpha-adrenomimetic (mezatone) during the first week after birth. This effect was enhanced by prolonged cold exposure of adult animals. On the contrary, the norepinephrine-induced increase of heat losses from the tail surface was higher in new-born rats, exposed to cold or treated with beta-adrenomimetic (novodrine) than in control or mezatone-treated groups. The effects of neonatal stress or pharmacological treatment on oxygen consumption and rectal temperature responses to norepinephrine were unsignificant.
M P
MP
Moshkin
V G
VG
Seliatitskaia
E I
EI
Zhigulina
T V
TV
Arshinova
D000818:Animals; D000831:Animals, Newborn; D001833:Body Temperature Regulation / Q000187:drug effects*; D003080:Cold Temperature; D006234:Handling, Psychological; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*; D010656:Phenylephrine / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D013315:Stress, Psychological / Q000503:physiopathology*; D013696:Temperature; D013997:Time Factors; D014284:Triiodothyronine / Q000494:pharmacology
D014284:Triiodothyronine; D010656:Phenylephrine; D007545:Isoproterenol; D009638:Norepinephrine