[The phenomenon of the enhancement of the formation of lymphocytotoxic alloimmune antibodies during the use of plasmapheresis].
Apheresis was applied in 17 patients with hypoplastic anemia, myelodysplastic syndrome, chronic renal failure and other diseases sensitized to HLA. Apheresis was done for removal of anti-HLA antibodies and prevention of nonhemolytic transfusion reactions. Multiple massive apheresis led to a marked decrease in the antibody level. After the first or second apheresis with removal of 700.0-2000.0 ml of plasma weekly half of the patients showed increasing titres of lymphocytotoxic antibodies.
Zotikov
E A
EA
Babaeva
A G
AG
Kalinin
N N
NN
Vasil'eva
M N
MN
Golovkina
L L
LL
Shtyreva
E M
EM
Mikhaĭlova
E A
EA
Biriukova
L S
LS
D000961:Antilymphocyte Serum / Q000096:biosynthesis* / Q000097:blood; D005260:Female; D006680:HLA Antigens / Q000276:immunology; D006402:Hematologic Diseases / Q000276:immunology / Q000628:therapy; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis* / Q000097:blood; D008297:Male; D010956:Plasmapheresis
D000961:Antilymphocyte Serum; D006680:HLA Antigens; D007518:Isoantibodies