Volume-dependent potassium transport in camel red blood cells.
In this study the volume-dependent, ouabain-resistant K+ influx and efflux in camel red blood cells were measured with the tracer 86Rb+. The results showed that the camel erythrocytes do not have the Na(+)-K+ cotransport. The cell swelling increases a ouabain-resistant K+ influx and shrinkage decreases it nearly two-fold. The swelling-stimulated K+ influx and efflux were chloride dependent. The anion dependence of K+ influx in swollen cells was as follows: Br- > Cl- > NO3. The pH-dependent curve for swelling-stimulated potassium influx, and the active K+ influx in camel erythrocytes were determined. The findings indicate that camel erythrocytes' potassium transport system has many similarities to other mammalian species.
Gharaibeh
N S
NS
Department of Physiology and Biochemistry, Jordan University of Science and Technology, Irbid.
Rawashdeh
N M
NM
D000818:Animals; D000838:Anions / Q000494:pharmacology; D001692:Biological Transport; D002162:Camelus / Q000097:blood*; D002352:Carrier Proteins / Q000097:blood; D004912:Erythrocytes / Q000166:cytology* / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D009994:Osmolar Concentration; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium / Q000097:blood* / Q000493:pharmacokinetics; D028021:Sodium-Potassium-Chloride Symporters; D000254:Sodium-Potassium-Exchanging ATPase / Q000502:physiology
D000838:Anions; D002352:Carrier Proteins; D028021:Sodium-Potassium-Chloride Symporters; D010042:Ouabain; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium