[Isolation and structure determination of biologically active peptides from the bone marrow].
Two hexapeptides affecting pain sensitivity were isolated from the bone marrow cells supernatant, shown to have primary structure Leu-Val-Val-Tyr-Pro-Trp and Phe-Leu-Gly-Phe-Pro-Thr, and synthesized by the solid phase method. In physico-chemical and biological properties the synthetic peptides were identical to the peptides isolated.
S A
SA
Gur'ianov
L A
LA
Fonina
A A
AA
Mikhaĭlova
D000595:Amino Acid Sequence; D000818:Animals; D001853:Bone Marrow / Q000737:chemistry*; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000502:physiology; D017288:Pain Threshold; D013552:Swine
D009842:Oligopeptides