[Adenoid cystic cancer of the breast. Case report and meta-analysis of the literature].
Adenoid-cystic carcinoma of the breast is considered a rare entity with a comparatively favourable prognosis. We report the case of a 58 year old woman and review another 150 cases published to date in the pertinent literature. The clinical course and outcome of 99 patients was evaluated by meta-analysis. Recurrence-free ten-year survival was calculated at 85.1 percent following mastectomy and at 45.7 percent after breast-conserving therapy (p < 0.05). Six of ten local recurrences and 7 of 8 distant metastases occurred 5 years or later after initial treatment. It is concluded that patients with adenoid-cystic carcinoma of the breast should be treated by primary mastectomy and extended follow-up is recommended.
Pathologisches Institut, Universität Heidelberg.
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Sinn
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Lehnert
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Otto
D014408:Biomarkers, Tumor / Q000032:analysis; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D015411:Mastectomy, Modified Radical; D008875:Middle Aged; D011379:Prognosis
D014408:Biomarkers, Tumor