Scanning electron microscopic study of Trichinella pseudospiralis muscle phase after modulation of host response using an immunostimulant drug.
In a previous study, evident collagen deposition around T. pseudospiralis larvae was noticed after administration of Levamisole to infected mice. The present investigation was undertaken to confirm these findings. Scanning electron microscopic examination revealed multiple clear cystic formations on the surface of the diaphragm muscle. The present investigation was undertaken to confirm these findings. Scanning electron microscopic examination revealed multiple clear cystic formations on the surface of the diaphragm muscle. The presence of such structures was seen to be more frequent when the drug was given as early as the 6th day post infection. Membrane like structure was observed around T. pseudospiralis larvae, an interesting finding which was by far not reported before.
Department of Parasitology, Faculty of Medicine, Alexandria University, Egypt.
I H
IH
Hegazy
L M
LM
Boulos
D000818:Animals; D003094:Collagen / Q000096:biosynthesis; D003964:Diaphragm / Q000469:parasitology* / Q000648:ultrastructure; D007814:Larva / Q000648:ultrastructure; D007978:Levamisole / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008855:Microscopy, Electron, Scanning; D014234:Trichinella / Q000648:ultrastructure*; D014235:Trichinellosis / Q000188:drug therapy / Q000276:immunology / Q000469:parasitology*
D007978:Levamisole; D003094:Collagen