[Preliminary study on antenatal diagnosis of cytomegalovirus infection by polymerase chain reaction (PCR) technique].
Polymerase chain reaction (PCR) technique were used for screening intrauterine human cytomegalovirus (CMV) infection in pregnant women with 10-16 gestational weeks, 31 out of 106 blood specimens investigated were CMV DNA positive. Then CMV DNA in amniotic fluid was tested in 23 of the 31 pregnant women with CMV DNA positive, and AFP was examined at the same time. 11 cases were CMV DNA positive in the amniotic fluid. Of the 9 fetus or neonates monitored, CMV DNA were detected in all umbilical blood, and in liver tissue of 4 aborted fetus. Clinical symptoms were also supportive of intrauterine CMV infection.
Li
S K
SK
People's Hospital of Panyu City, Guangdong.
D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000382:microbiology; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D011296:Prenatal Diagnosis / Q000379:methods*
D004279:DNA, Viral