Peripheral nervous system involvement in a large cohort of human immunodeficiency virus-infected individuals.
OBJECTIVE
In individuals who were infected with the human immunodeficiency virus (HIV) we determined the prevalence of peripheral neuropathies (PNs) and explored the relationship between immunologic competence and nerve function.


METHODS
Cohort survey.


METHODS
US Air Force medical center.


METHODS
Population based. Seven hundred ninety-eight of 817 HIV-positive personnel identified by US Air Force HIV screening program from 1985 to 1989. Average age of cohort was 29.2 years. The majority were male with early-stage HIV disease.


METHODS
Neurologists examined all subjects for symptoms and signs of PN. We grouped patients by CD4 T-lymphocyte count. We further studied 300 HIV-infected volunteers without clinical evidene of PN by nervex
Department of Neurology, Wilford Hall US Air Force Medical Center, Lackland Air Force Base, Tex.
R J
RJ
Barohn
G S
GS
Gronseth
B R
BR
LeForce
A L
AL
McVey
S A
SA
McGuire
C A
CA
Butzin
R B
RB
King
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000276:immunology / Q000503:physiopathology; D015704:CD4 Antigens / Q000032:analysis; D002452:Cell Count; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D009431:Neural Conduction; D010525:Peripheral Nerves / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*; D013601:T-Lymphocytes / Q000276:immunology
D015704:CD4 Antigens