Adult onset nemaline myopathy: a distinct nosologic entity?
A 61-year-old woman presented progressive distal weakness and wasting of her upper limbs spreading to the shoulder girdle and to the neck muscles. Creatine kinase, cerebrospinal fluid, spinal X-ray and spinal nuclear magnetic resonance were normal. Electromyography showed myopathic alterations. Muscle biopsy showed abundant rods in many fibres. Prednisone 75 mg/die for two months did not modify the symptoms.
Palmucci
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L
Paolo Peirolo Centre for Neuromuscular Diseases, Università di Torino, Italy.
Doriguzzi
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C
Mongini
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T
Chiadò-Piat
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L
D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008875:Middle Aged; D009123:Muscle Hypotonia / Q000473:pathology*; D009132:Muscles / Q000473:pathology; D009133:Muscular Atrophy / Q000473:pathology*; D009210:Myofibrils / Q000648:ultrastructure; D009468:Neuromuscular Diseases / Q000473:pathology*