[2-Guanidino-4(3H)-quinazolinones with chemotherapeutic activities].
Partially introduction of the biguanide structure into heterocyclic systems leads to various substituted 2-guanidino-4(3H)-chinazolinones. The compounds exhibit significant antimycotic and gyrase-inhibiting activities.
Kreutzberger
A
A
Institut für Pharmazie, Johannes-Gutenberg-Universität Mainz.
Balbach
S
S
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011799:Quinazolines / Q000138:chemical synthesis*; D059005:Topoisomerase II Inhibitors
D000935:Antifungal Agents; D011799:Quinazolines; D059005:Topoisomerase II Inhibitors