Design of potent non-peptide competitive antagonists of the human bradykinin B2 receptor.
Department of Medicinal Chemistry and Enzymology, Sterling Winthrop Pharmaceutical Research Division, Pennsylvania 19426-0900.
J M
JM
Salvino
P R
PR
Seoane
B D
BD
Douty
M M
MM
Awad
R E
RE
Dolle
W T
WT
Houck
D M
DM
Faunce
D G
DG
Sawutz
D000595:Amino Acid Sequence; D000818:Animals; D001667:Binding, Competitive; D006168:Guinea Pigs; D006801:Humans; D008969:Molecular Sequence Data; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D009281:Naphthalenes / Q000138:chemical synthesis / Q000494:pharmacology; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D018002:Receptors, Bradykinin; D017981:Receptors, Neurotransmitter / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013329:Structure-Activity Relationship
D009281:Naphthalenes; D009943:Organophosphorus Compounds; D018002:Receptors, Bradykinin; D017981:Receptors, Neurotransmitter