Inhibition of pancreatic islet beta cell function by tumor necrosis factor is blocked by a soluble tumor necrosis factor receptor.
Department of Surgery, University of Minnesota, Minneapolis.
A C
AC
Farney
E
E
Xenos
D E
DE
Sutherland
M
M
Widmer
E
E
Stephanian
M J
MJ
Field
D B
DB
Kaufman
R B
RB
Stevens
B
B
Blazar
J
J
Platt
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000235:genetics; D007074:Immunoglobulin G / Q000235:genetics; D066298:In Vitro Techniques; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D011956:Receptors, Cell Surface / Q000235:genetics / Q000502:physiology*; D018124:Receptors, Tumor Necrosis Factor; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*
D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D007328:Insulin; D011956:Receptors, Cell Surface; D018124:Receptors, Tumor Necrosis Factor; D011993:Recombinant Fusion Proteins; D014409:Tumor Necrosis Factor-alpha