Effect of dietary aluminum and vitamin D interaction on growth and calcium and phosphorus metabolism of broiler chicks.
The interaction of dietary aluminum (as aluminum sulfate) and vitamin D on growth performance and calcium and phosphorus metabolism was investigated using male broiler chicks. A corn-soybean broiler starter diet, containing .88% Ca and .45% available P and without added cholecalciferol (vitamin D3), was fed with 0 or .2% Al and with 0, 100, or 200 ICU of vitamin D3/kg of diet in a complete factorial arrangement. Four replicate cages of 10 chicks, 1 day of age, were assigned to each dietary treatment. Average body weight gain (328 versus 545 g), feed intake (611 versus 784 g), gain:feed (.54 versus .68), and plasma inorganic P (4.2 versus 6.7 mg/dL) were significantly reduced (P < .05) in chicks fed diets with .2% Al, compared with those fed 0% Al. These four variables were improved by increasing the level of vitamin D3 in the diet from 0 to 100 ICU/kg. However, further improvements were not obtained by elevating the vitamin D3 level to 200 ICU/kg. There were significant interactions of Al and vitamin D3 on gain, feed intake, and gain:feed, but not on plasma P. Gain and feed intake were significantly decreased by Al at each level of vitamin D3. Plasma total Ca was significantly increased by vitamin D3, but was unaffected by Al. Increasing the level of dietary vitamin D3 did not completely alleviate the negative effects of Al.
Hussein
A S
AS
Department of Animal Sciences, University of Kentucky, Lexington 40546-0215.
Cantor
A H
AH
Pescatore
A J
AJ
Johnson
T H
TH
D000535:Aluminum / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D002118:Calcium / Q000097:blood*; D002645:Chickens / Q000254:growth & development / Q000502:physiology*; D002762:Cholecalciferol / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D008274:Magnesium / Q000097:blood; D008297:Male; D010758:Phosphorus / Q000097:blood*; D015430:Weight Gain / Q000187:drug effects
D002762:Cholecalciferol; D010758:Phosphorus; D000535:Aluminum; D008274:Magnesium; D002118:Calcium