[The value of dynamic MRT in the perfusion evaluation of pelvic tumors under hyperthermia].
For the purpose of assessing perfusion of deep seated pelvic tumours 22 dynamic MR studies were carried out and correlated with relevant CT studies as well as with the intratumoural distribution of temperature under hyperthermia in different areas. Using changes of signal intensity, dynamic MR could thus distinguish between well and poorly perfused tumours, besides supplying reliable information on inhomogeneities in tumour perfusion. Altogether, a correlation of 0.92 (p < 0.001) was found between MR and CT and 0.72 (p < 0.001) between MR and the steady state determination of intratumoural temperature. Thus, dynamic MR provides prognostic information concerning therapeutic temperatures (> = 42 degrees C) in tumours and therefore their response to hyperthermia.
Röntgendiagnostisches Zentralinstitut, Universitätsklinikum Essen.
K W
KW
Sievers
H J
HJ
Feldmann
J
J
Füller
M
M
Molls
H
H
Sack
D010478:Chemotherapy, Cancer, Regional Perfusion; D006801:Humans; D006979:Hyperthermia, Induced; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000532:radiotherapy / Q000628:therapy; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000532:radiotherapy / Q000628:therapy; D010386:Pelvic Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy / Q000628:therapy; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000628:therapy; D014057:Tomography, X-Ray Computed