Fresh frozen plasma and edrophonium in a patient with a plasma cholinesterase deficiency.
A 35-year-old woman undergoing laparoscopic sterilisation developed prolonged apnoea after suxamethonium. Fresh frozen plasma was given to replenish plasma cholinesterase, but recovery of neuromuscular transmission was not accelerated. Routine use of quantitative neuromuscular monitoring simplified her postoperative management.
Smith
D C
DC
Department of Anaesthesia, Western Infirmary, Glasgow.
Ridley
S A
SA
Donaldson
K F
KF
D000328:Adult; D001049:Apnea / Q000139:chemically induced* / Q000628:therapy; D002802:Cholinesterases / Q000172:deficiency*; D004491:Edrophonium / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008991:Monitoring, Physiologic; D009469:Neuromuscular Junction / Q000502:physiology; D010949:Plasma; D011183:Postoperative Complications / Q000139:chemically induced; D013390:Succinylcholine / Q000009:adverse effects*; D009435:Synaptic Transmission / Q000502:physiology
D004491:Edrophonium; D002802:Cholinesterases; D013390:Succinylcholine