Bacterial adherence to bioinert and bioactive materials studied in vitro.
In vitro, bioinert stainless steel and titanium alloy, and bioactive sintered hydroxyapatite and hydroxyapatite-coated titanium materials were exposed to Staphylococcus epidermidis to study bacterial adhesion. Scanning electron microscopy showed that fibrous strands interconnected the adherent bacteria, and that background matrix enclosed bacterial colonies. This adherent mode of growth may reduce the susceptibility of the bacteria to host clearance mechanisms and antibiotic therapy. Adherence assays revealed that bacterial adherence to sintered hydroxyapatite was higher than to the other 3 materials.
Oga
M
M
Department of Orthopedics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Arizono
T
T
Sugioka
Y
Y
D000497:Alloys; D001422:Bacterial Adhesion; D001672:Biocompatible Materials; D017886:Durapatite; D006882:Hydroxyapatites; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D013193:Stainless Steel; D013212:Staphylococcus epidermidis / Q000648:ultrastructure*; D014025:Titanium
D000497:Alloys; D001672:Biocompatible Materials; D006882:Hydroxyapatites; D013193:Stainless Steel; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium