Fine needle aspiration of a renal cell carcinoma with eosinophilic globules. A case report.
Fine needle aspiration (FNA) of a renal cell carcinoma with hyaline eosinophilic globules is presented. The cytology of the tumor cells was characterized by intracytoplasmic, dense, well-circumscribed globules that had a bright magenta appearance on Diff-Quik staining. Tissue sections demonstrated the globules to be located predominantly within the cytoplasm of the clear cells of the carcinoma. Immunohistochemical and ultrastructural evaluation is discussed, as is the significance of this finding.
Department of Pathology, Mount Sinai Medical Center, New York, New York 10029.
P
P
Unger
K
K
Hague
G
G
Klein
R E
RE
Gordon
S N
SN
Thung
A
A
Szporn
D000236:Adenoma / Q000378:metabolism / Q000473:pathology; D000310:Adrenal Gland Neoplasms / Q000378:metabolism / Q000473:pathology; D000328:Adult; D001707:Biopsy, Needle; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D004802:Eosinophilia / Q000473:pathology; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000473:pathology; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed