[Antimutagenic action of superoxide dismutase on sodium azide- and nitrosoguanidine-induced mutagenesis in Salmonella typhimurium TA 1535].
It was shown that superoxide dismutase (SOD) decreased the mutagenic action of sodium azide (NaN3) and N-methyl-N'-nitro-N-nitrosoguanidine in Salmonella typhimurium TA1535. Catalase and quenchers of hydroxyl radicals showed, unlike SOD no effect on the mutagenicity of NaN3. Cell extract from propionic acid bacteria also possessed the antimutagenic activity, only partially depending on the SOD activity.
Vorob'eva
L I
LI
Cherdyntseva
T A
TA
Aver'ianov
A A
AA
Abilev
S K
SK
D016587:Antimutagenic Agents / Q000494:pharmacology*; D001386:Azides; D002374:Catalase / Q000494:pharmacology; D005609:Free Radicals; D006878:Hydroxides; D017665:Hydroxyl Radical; D007202:Indicators and Reagents; D008769:Methylnitronitrosoguanidine; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics*; D019810:Sodium Azide; D013482:Superoxide Dismutase / Q000494:pharmacology*
D016587:Antimutagenic Agents; D001386:Azides; D005609:Free Radicals; D006878:Hydroxides; D007202:Indicators and Reagents; D008769:Methylnitronitrosoguanidine; D017665:Hydroxyl Radical; D019810:Sodium Azide; D002374:Catalase; D013482:Superoxide Dismutase