N-acyl-L-tryptophan benzyl esters: potent substance P receptor antagonists.
MacLeod
A M
AM
Merck, Sharp and Dohme Research Laboratories, Harlow, Essex, U.K.
Merchant
K J
KJ
Cascieri
M A
MA
Sadowski
S
S
Ber
E
E
Swain
C J
CJ
Baker
R
R
D001593:Benzyl Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D004952:Esters / Q000138:chemical synthesis / Q000494:pharmacology; D006801:Humans; D018040:Receptors, Neurokinin-1; D017981:Receptors, Neurotransmitter / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D014364:Tryptophan / Q000031:analogs & derivatives*
D001593:Benzyl Compounds; D004952:Esters; D018040:Receptors, Neurokinin-1; D017981:Receptors, Neurotransmitter; D014364:Tryptophan