Adenosine in the heart: its emerging roles.
An important regulator of cardiac rhythm and coronary blood flow, adenosine is finding valuable applications in treatment and diagnosis. It should soon be available for cardiac imaging and eventually as a protective agent against acute myocardial infarction and reperfusion injury. Study of adenosine's uses is providing insights into its biologic effects in a variety of organ systems.
Pelleg
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Likoff Cardiovascular Institute, Hahnemann University, Philadelphia.
D000241:Adenosine / Q000502:physiology / Q000627:therapeutic use; D000818:Animals; D001783:Blood Flow Velocity / Q000187:drug effects*; D015220:Calcium Channels / Q000187:drug effects; D002986:Clinical Trials as Topic; D003331:Coronary Vessels / Q000187:drug effects*; D003937:Diagnosis, Differential; D004195:Disease Models, Animal; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D005080:Exercise Test; D006339:Heart Rate / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D015221:Potassium Channels / Q000187:drug effects; D011983:Receptors, Purinergic / Q000187:drug effects / Q000502:physiology; D015398:Signal Transduction; D013614:Tachycardia, Paroxysmal / Q000175:diagnosis / Q000188:drug therapy; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000188:drug therapy
D015220:Calcium Channels; D015221:Potassium Channels; D011983:Receptors, Purinergic; D000241:Adenosine