Synthesis and biological properties of RWJ 22108, a bronchoselective calcium channel blocker.
Dodd
J H
JH
R.W. Johnson Pharmaceutical Research Institute, Raritan, NJ 08869.
Schwender
C F
CF
Conley
R A
RA
Moore
J B
JB
Ritchie
D M
DM
Fabian
A C
AC
Fenk
C J
CJ
Bourcet
E
E
Gray-Nunez
Y
Y
Kirchner
T
T
D000818:Animals; D001249:Asthma / Q000188:drug therapy*; D001980:Bronchi / Q000187:drug effects*; D001993:Bronchodilator Agents / Q000138:chemical synthesis / Q000494:pharmacology; D002121:Calcium Channel Blockers / Q000138:chemical synthesis* / Q000494:pharmacology; D004285:Dogs; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology; D011817:Rabbits
D001993:Bronchodilator Agents; D002121:Calcium Channel Blockers; D011725:Pyridines; C080337:RWJ 22108