Experimental infection of weaned calves and lambs with two strains of bovine adenovirus type 2.
The pathogenicity of two genetically different strains of bovine adenovirus type 2 (BAV-2) was tested in a double cross experimental infection of weaned lambs and calves. One of the virus strains was isolated from cattle and represented BAV-2 subgroup "A", while the other was isolated from sheep and belonged to subgroup "B" (Belák et al., 1983). The two virus strains caused infection both in lambs and calves; the viruses were repeatedly reisolated and definite seroconversion was found in all four groups. However, remarkable differences were observed in the pathogenicity: the most intensive virus multiplication and shedding, the most severe clinical symptoms and histopathological lesions were observed in the lamb group infected with the ovine isolate.
Rusvai
M
M
Department of Microbiology and Infectious Diseases, University of Veterinary Science, Budapest, Hungary.
Glávits
R
R
Kucsera
L
L
Belák
S
S
D000256:Adenoviridae / Q000472:pathogenicity*; D000257:Adenoviridae Infections / Q000382:microbiology / Q000662:veterinary*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D005260:Female; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology*