Postmortem comparative analysis of titanium and hydroxyapatite porous-coated femoral implants retrieved from the same patient. A case study.
The results of bilateral postmortem analysis of titanium and plasma-sprayed hydroxyapatite (HA) porous-coated femoral components of the same Anatomic Porous Replacement design retrieved from a 35-year-old female donor are reported. Analysis was conducted using backscattered electron imaging, histology, and radiographic techniques. The appositional bone index, percent bone ingrowth, and mineral content were measured for both implants. The results showed a 177% higher appositional bone index (P = .014) for the HA porous-coated Anatomic Porous Replacement component compared to the titanium Anatomic Porous Replacement component. Backscattered electron analysis showed 50% more bone in the HA porous-coated implant (P = .028). The mineral content analysis demonstrated that the bone ingrown into the HA porous-coated device was 23% less mineralized (P = .016). The data from this case study suggested that plasma-sprayed HA porous-coated implants may assist in increasing the amount of bone ingrowth and skeletal attachment in total hip arthroplasties.
Bone and Joint Research Labs, VA Medical Center, Salt Lake City, UT 84148.
R D
RD
Bloebaum
K N
KN
Bachus
M H
MH
Rubman
L D
LD
Dorr
D000328:Adult; D001171:Arthritis, Juvenile / Q000601:surgery; D015519:Bone Density; D017886:Durapatite; D005260:Female; D005269:Femur / Q000033:anatomy & histology; D006622:Hip Prosthesis; D006801:Humans; D006882:Hydroxyapatites; D016348:Osseointegration; D011474:Prosthesis Design; D014025:Titanium
D006882:Hydroxyapatites; D017886:Durapatite; D014025:Titanium