Ketoacidosis in diabetic pregnancy.
A study was carried out to determine the incidence of maternal ketoacidosis in 635 insulin-treated diabetic pregnancies managed in a combined antenatal/diabetic clinic between 1971 and 1990. A total of 11 episodes occurred, representing 1.73% of diabetic pregnancies of which 9 were in the antenatal period. Overall fetal loss including spontaneous abortion was 22%, but there was only one fetal death in the seven episodes of ketoacidosis in the second and third trimesters. Ketoacidosis is an infrequent occurrence in diabetic pregnancy managed in a combined clinic and is not associated with a high fetal loss after the first trimester.
General Hospital, Birmingham, UK.
J A
JA
Kilvert
H O
HO
Nicholson
A D
AD
Wright
D000022:Abortion, Spontaneous; D000293:Adolescent; D000328:Adult; D001639:Bicarbonates / Q000097:blood; D016883:Diabetic Ketoacidosis / Q000453:epidemiology*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007328:Insulin / Q000627:therapeutic use; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D011295:Prenatal Care; D012189:Retrospective Studies
D001639:Bicarbonates; D006442:Glycated Hemoglobin; D007328:Insulin