Nonsurgical treatment of heterotopic pregnancy: a report of six cases.
OBJECTIVE
To evaluate nonsurgical management of heterotopic pregnancy.


METHODS
Retrospective case series.


METHODS
Department of Obstetrics and Gynecology (Antoine Béclère Hospital, Clamart, France, Paris-Sud University).


METHODS
Six women with heterotopic pregnancy who conceived in four cases after ovulation induction.


METHODS
Transvaginal ultrasound (US)-guided aspiration/injection of potassium chloride (KCl) was performed in three cornual pregnancies with alive embryo. Expectant management was realized in three other cases. The regression was followed by serial US examination.


METHODS
Early and late complications related to the procedure, outcome of intrauterine pregnancy (IUP).


RESULTS
Five of six patients were treated successfully (3 with KCl and 2 after expectant management). Three of these five patients had a spontaneous vaginal delivery, and two abortions occurred in the remaining two patients. Salpingectomy had to be performed in one case 10 days after medical treatment. This twin pregnancy ended with an abortion at 23 weeks of amenorrhea. Four cornual heterotopic pregnancies were treated successfully. No complication occurred after the initial management.


CONCLUSIONS
Ultrasound permits a reliable and early diagnosis of heterotopic pregnancy. In such cases nonsurgical management is an efficient alternative with a good IUP prognosis.
Department of Obstetrics and Gynecology, Antoine Béclère Hospital, Clamart, France.
H
H
Fernandez
C
C
Lelaidier
S
S
Doumerc
P
P
Fournet
F
F
Olivennes
R
R
Frydman
D000328:Adult; D005260:Female; D006801:Humans; D007267:Injections; D011189:Potassium Chloride / Q000008:administration & dosage* / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications; D011271:Pregnancy, Ectopic / Q000628:therapy*; D011272:Pregnancy, Multiple; D013396:Suction; D014427:Twins; D014465:Ultrasonics; D014599:Uterus
D011189:Potassium Chloride