The role of palatability in the food intake response of rats fed high-protein diets.
Male albino rats, trained to eat over a 3-h period, reduced their food intake from 0.38 +/- 0.04 g of a low-protein diet to 0.14 +/- 0.03 g of a high-protein diet, within 1 min following diet presentation. Since this occurred before the metabolic effects of a high-protein diet should be seen, we suggest that, although neophobia could play a role, poor initial palatability may be a significant factor in this early depression in food intake. To differentiate initial palatability from responses to metabolic feedback, we designed a feeding paradigm using positive or negative taste cues and a 6-h feeding period. Pre-treatment with a 6% casein diet containing 0.15% quinine HCl resulted in near equal consumption of a 75% casein and a 6% casein unadulterated diet during the first 30 min after introduction of the diets. Later, the rate of consumption of the high-protein diet was lower than of the lower-protein diet, likely the result of post-absorptive factors. We suggest that prevention of the early reduction in food intake due to initial palatability may facilitate study of post-absorptive response(s) to high-protein diets.
McArthur
L H
LH
Department of Nutrition Sciences, University of Vermont 05405.
Kelly
W F
WF
Gietzen
D W
DW
Rogers
Q R
QR
D000818:Animals; D002364:Caseins / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage*; D004435:Eating / Q000502:physiology*; D005246:Feedback; D007700:Kinetics; D008297:Male; D011803:Quinine / Q000008:administration & dosage; D051381:Rats; D017207:Rats, Sprague-Dawley; D012439:Saccharin / Q000008:administration & dosage; D013649:Taste
D002364:Caseins; D004044:Dietary Proteins; D011803:Quinine; D012439:Saccharin