Technetium-99m(V)dimercaptosuccinic acid uptake in intra-abdominal massive deposit of amyloid protein.
Technetium-99m(V)dimercaptosuccinic acid (DMSA) scintigraphy was performed in two patients with pathologically confirmed primary amyloidosis. Both patients had tumor-like deposits of AL-type amyloid in the abdomen. Marked uptake of the tracer by the amyloid deposits was noted. Technetium-99m-(V)DMSA scintigraphy appears to be useful in detecting the distribution of amyloid deposits and in determining the appropriate site for biopsy.
Kobayashi
H
H
Department of Radiology and Nuclear Medicine, Kyoto University, Faculty of Medicine, Japan.
Sakahara
H
H
Itoh
T
T
Kudoh
T
T
Takagi
T
T
Shibuya
K
K
Nomura
S
S
Hosono
M
M
Endo
K
K
Konishi
J
J
D000005:Abdomen / Q000000981:diagnostic imaging*; D000368:Aged; D000682:Amyloid / Q000378:metabolism*; D000686:Amyloidosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics; D011877:Radionuclide Imaging; D004113:Succimer / Q000493:pharmacokinetics; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
D000682:Amyloid; D015609:Organotechnetium Compounds; C035222:amyloid protein AL; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D004113:Succimer