[The enhancement by hydrocortisone of the hydro-osmotic effect of vasopressin and cAMP in the frog bladder wall].
Hydroosmotic effect of vasopressin enhanced by the addition of hydrocortisone to serosal Ringer solution of frog urinary bladder. The osmotic permeability of the urinary bladder wall increased after inhibition of cAMP phosphodiesterase by isobutylmethylxanthine followed by the addition of cAMP; hydrocortisone modulated the action of cAMP phosphodiesterase and consequently increased the effect of isobutylmethylxanthine.
Natochin
Iu V
IuV
Shakhmatova
E I
EI
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002463:Cell Membrane Permeability / Q000187:drug effects; D000242:Cyclic AMP / Q000494:pharmacology*; D004357:Drug Synergism; D006854:Hydrocortisone / Q000494:pharmacology*; D009995:Osmosis / Q000187:drug effects; D011896:Rana temporaria; D001743:Urinary Bladder / Q000187:drug effects* / Q000502:physiology; D014667:Vasopressins / Q000494:pharmacology*; D014867:Water / Q000378:metabolism*
D014867:Water; D014667:Vasopressins; D000242:Cyclic AMP; D006854:Hydrocortisone