Long-acting antirheumatic drugs induce differentiation of cells of the monocyte-macrophage lineage and alter the expression of cytokines and IL-1 receptor antagonist.
Allison
A C
AC
Syntex Discovery Research, Palo Alto, California 94304.
Waters
R V
RV
D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D016207:Cytokines / Q000096:biosynthesis*; D003692:Delayed-Action Preparations; D006801:Humans; D008264:Macrophages / Q000187:drug effects*; D009000:Monocytes / Q000187:drug effects*; D017472:Receptors, Interleukin-1 / Q000037:antagonists & inhibitors*
D000893:Anti-Inflammatory Agents; D016207:Cytokines; D003692:Delayed-Action Preparations; D017472:Receptors, Interleukin-1