[The effect of fluctuating currents on the time course of apomorphine-induced stereotypy in rats].
The external rhythmogenic influence (repeated fluctuation low intensity) disorganized the time-course and attenuated the apomorphine-induced stereotyped behavior in rats. A decrease in the number of 4-9-minute waves on chronograms in comparison with control an animals indicated reduction of stability of the pharmacological response and the rapid formation of tolerance to the drug.
Popov
A V
AV
Tsedinov
B P
BP
Arushanian
E B
EB
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D001332:Automatism / Q000139:chemically induced / Q000503:physiopathology; D004558:Electric Stimulation; D010507:Periodicity; D051381:Rats; D013239:Stereotyped Behavior / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors
D001058:Apomorphine