Autoionization reaction of phosgene (OCCl2) studied by electron paramagnetic resonance/spin trapping techniques.
The reaction of phosgene with nitrone spin traps was investigated using electron paramagnetic resonance (EPR)/spin trapping techniques. Evidence for the intermediacy of a carbamoyl monochloride intermediate was obtained. Isotopic substitution of 13C-phosgene was employed to verify the hyperfine coupling constant assignments. The implications of these observations on pulmonary damage caused by inhalation of phosgene are mentioned.
U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5425.
C M
CM
Arroyo
F
F
Feliciano
D L
DL
Kolb
J R
JR
Keeler
S R
SR
Millette
R R
RR
Stotts
D004578:Electron Spin Resonance Spectroscopy / Q000379:methods; D005609:Free Radicals; D009589:Nitrogen Oxides / Q000737:chemistry; D010705:Phosgene / Q000737:chemistry*; D013113:Spin Labels
D005609:Free Radicals; D009589:Nitrogen Oxides; D013113:Spin Labels; D010705:Phosgene