A polymorphism in the 5' region of coagulation factor VII gene (F7) caused by an inserted decanucleotide.
We describe a polymorphism in the 5' region of the coagulation factor VII (FVII) gene, originating from a decanucleotide (CCTATATCCT) insert present in the less frequent allele. This marker can be detected by restriction analysis of polymerase chain reaction products.
Marchetti
G
G
Centro di Studi Biochimici delle Patologie del Genoma Umano, Università di Ferrara, Italy.
Patracchini
P
P
Papacchini
M
M
Ferrati
M
M
Bernardi
F
F
D000483:Alleles; D001483:Base Sequence; D002882:Chromosomes, Human, Pair 13; D004247:DNA / Q000032:analysis; D004251:DNA Transposable Elements; D005167:Factor VII / Q000235:genetics*; D005787:Gene Frequency; D005799:Genes, Dominant; D006801:Humans; D008969:Molecular Sequence Data; D009841:Oligonucleotides; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic
D004251:DNA Transposable Elements; D009841:Oligonucleotides; D005167:Factor VII; D004247:DNA