[Liver microcirculative disturbance in schistosomiasis portal hypertension].
Using reing resin vascular casts, ink perfusion, VG and electron microscope. We studied the liver microcirculative disturbance in rabbits (n = 20) and mice (n = 10) with chronic schistosomiasis. The results showed a decrease in the liver sinusoid number, tortuosity of the terminal branches of the portal vein, formation of a basement membrane in the space of Disse, capillarization of the sinusoid. These results suggest that liver microcirculative disturbance can contribute to schistosomiasis portal hypertension.
Department of Basic Medicine, Tongji Hospital, Tongji Medical University.
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Yang
D000818:Animals; D005260:Female; D006975:Hypertension, Portal / Q000209:etiology / Q000503:physiopathology*; D008099:Liver / Q000098:blood supply* / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008833:Microcirculation / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D012554:Schistosomiasis japonica / Q000150:complications / Q000473:pathology / Q000503:physiopathology*