Diet as a risk factor for peripheral arterial disease in the general population: the Edinburgh Artery Study.
The Edinburgh Artery Study included a cross-sectional survey of 1592 men and women (aged 55-74 y). One aim was to examine relationships between an indicator of peripheral arterial disease, the ankle brachial pressure index (ABPI), and dietary factors. Nutrient intake was derived from a food-frequency questionnaire. Higher frequency of consumption of fiber-containing foods was associated with greater mean ABPI in males and higher consumption of meat and meat products were significantly associated with low mean ABPI in males and females. In a multiple linear regression with ABPI as outcome and energy-adjusted nutrients as predictors, cereal fiber (P = 0.02) and alcohol (P = 0.04) were positively associated with the ABPI in males but not in females. Dietary vitamin E(alpha-tocopherol) intake was positively associated with ABPI (P = 0.04) independently of smoking and other nutrients. Dietary vitamin C intake was significantly related to ABPI (P = 0.006) only among those who had ever smoked.
Wolfson Unit for Prevention of Peripheral Vascular Diseases, Department of Public Health Sciences, University of Edinburgh, UK.
P T
PT
Donnan
M
M
Thomson
F G
FG
Fowkes
R J
RJ
Prescott
E
E
Housley
D000368:Aged; D000842:Ankle / Q000098:blood supply; D001158:Arteries; D001205:Ascorbic Acid / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D001916:Brachial Artery / Q000502:physiology; D004032:Diet / Q000009:adverse effects*; D004043:Dietary Fiber / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008460:Meat; D008875:Middle Aged; D012044:Regression Analysis; D012307:Risk Factors; D012737:Sex Factors; D014652:Vascular Diseases / Q000209:etiology*
D004043:Dietary Fiber; D001205:Ascorbic Acid