The basic reproduction ratio for sexually transmitted diseases. Part 2. Effects of variable HIV infectivity.
In this paper we investigate the effects of variable infectivity on the spread of HIV in a heterosexual population where pair formation and separation are taken into account. We calculate the basic reproduction ratio as a function of the number of new partners during the infectious period, keeping the total number of contacts fixed. Numerical evidence suggests that the basic reproduction ratio decreases for variable infectivity if the average infectivity is kept constant.
Dietz
K
K
Institut für Medizinische Biometrie, Universität Tübingen, Germany.
Heesterbeek
J A
JA
Tudor
D W
DW
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000635:transmission*; D005260:Female; D006678:HIV; D015658:HIV Infections / Q000453:epidemiology / Q000635:transmission*; D006801:Humans; D008297:Male; D008433:Mathematics; D015233:Models, Statistical; D012749:Sexually Transmitted Diseases / Q000453:epidemiology / Q000635:transmission*