[The mitochondrial genome of the trypanosomatid kinetoplast: gene organization and transcription of the maxicircle DNA].
Modern data on genic organization and transcription of the mitochondrial genome in various trypanosomatids are reviewed, detailed genetical and transcriptional maps of the maxi-circle DNA being presented. A novel mechanism of the transcript processing in trypanosomatids, a so-called editing of mitochondrial RNAs, is especially emphasized. The phenomenon of the maxi-circle genome transcription initiation is discussed in addition to the regulatory mechanisms of expression and differential transcription of mitochondrial genes in trypanosomes.
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D000818:Animals; D002874:Chromosome Mapping; D004270:DNA, Circular / Q000235:genetics*; D018105:DNA, Kinetoplast; D004272:DNA, Mitochondrial / Q000235:genetics*; D016054:DNA, Protozoan / Q000235:genetics*; D005786:Gene Expression Regulation / Q000235:genetics; D017125:Genes, Protozoan; D014644:Genetic Variation / Q000235:genetics; D015183:Restriction Mapping; D014158:Transcription, Genetic / Q000235:genetics*; D014351:Trypanosomatina / Q000235:genetics*
D004270:DNA, Circular; D018105:DNA, Kinetoplast; D004272:DNA, Mitochondrial; D016054:DNA, Protozoan