[Reconstruction of the stapes superstructure with bioactive ceramics].
In this study we examined the feasibility of rebuilding a stable stapes superstructure for a new articulated ossicular chain by using bioactive ceramics. Dense hydroxylapatite and ceravital were tested in guinea pigs. The ceramic prosthesis was placed on the remnants of the footplate to create a bony connection without touching the tympanic membrane, thereby protecting it from relative movements. The implants were explanted together with the stapes footplate at six weeks and three months, respectively. Histologically, bony connections were found between all ceramic implants and the remnants of the crura even at six weeks and became more pronounced after three months.
Reide
W
W
Universitäts-HNO-Klinik Essen.
Dost
P
P
Missfeldt
N
N
Heine
J
J
Jahnke
K
K
D000818:Animals; D001672:Biocompatible Materials; D002516:Ceramics; D017886:Durapatite; D005260:Female; D006097:Granulation Tissue / Q000473:pathology; D006168:Guinea Pigs; D006882:Hydroxyapatites; D016348:Osseointegration / Q000502:physiology; D009998:Ossicular Prosthesis; D011474:Prosthesis Design; D013199:Stapes / Q000473:pathology; D013201:Stapes Surgery / Q000379:methods*
D001672:Biocompatible Materials; D006882:Hydroxyapatites; C031323:bio-vitroceramic AP40; D017886:Durapatite