[Study of structural features of macroglobulins complexed with plasmin].
Activities of plasmin and trypsin contained in complexes with alpha 2-macroglobulin, related to pregnancy alpha 2-glycoprotein and with protein A were studied in presence of various inhibitors with a molecular mass of 0.2-70.0 kDa. Specific characteristics of interaction between plasmin and these macroglobulins inhibitors as well as with alpha 1-inhibitor of proteinases, antithrombin III and alpha 2-antiplasmin were studied using electrophoresis and immunoblotting.
Zhabin
S G
SG
Zorin
N A
NA
Gorin
V S
VS
Lykova
O F
OF
D015153:Blotting, Western; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005341:Fibrinolysin / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D008259:Macroglobulins / Q000378:metabolism*; D008970:Molecular Weight; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000378:metabolism; D011480:Protease Inhibitors / Q000378:metabolism; D013205:Staphylococcal Protein A / Q000378:metabolism
D008259:Macroglobulins; D011257:Pregnancy Proteins; D011480:Protease Inhibitors; D013205:Staphylococcal Protein A; D005341:Fibrinolysin