Reye syndrome associated with subclinical varicella zoster virus and influenza A infection.
An association is reported between Reye syndrome and varicella zoster virus (VZV) infection in a 10-year-old boy who had serologic evidence of coinfection with VZV and influenza A H3N2, and exposure to salicylates. He developed VZV reinfection without skin lesions after family exposure and influenza A was community-acquired. Recent chickenpox contact should initiate VZV serologic studies in Reye syndrome patients, regardless of the chickenpox history or evidence of infection with other viruses.
Department of Pediatrics, University of British Columbia, Vancouver, Canada.
J
J
Hukin
A K
AK
Junker
E E
EE
Thomas
K
K
Farrell
D000596:Amino Acids / Q000097:blood; D000641:Ammonia / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects; D002648:Child; D006562:Herpes Zoster / Q000175:diagnosis* / Q000188:drug therapy; D014645:Herpesvirus 3, Human / Q000276:immunology; D006801:Humans; D009980:Influenza A virus / Q000276:immunology / Q000302:isolation & purification; D007251:Influenza, Human / Q000175:diagnosis* / Q000188:drug therapy; D008111:Liver Function Tests; D008297:Male; D009460:Neurologic Examination / Q000187:drug effects; D012202:Reye Syndrome / Q000139:chemically induced / Q000175:diagnosis*
D000596:Amino Acids; D000914:Antibodies, Viral; D000641:Ammonia; D001241:Aspirin