Spectrophotometric analysis of a pharmaceutical preparation by principal component regression.
The use of a principal component regression procedure for quantitative analytical control of pharmaceutical preparations was investigated. The procedure was applied to the simultaneous quantitation of the active compound and preservative of a syrup by resolving their respective UV spectra. The most suitable conditions for quantitation were established and the results were compared with those obtained by HPLC.
Departament de Química, Universitat Autònoma de Barcelona, Spain.
M
M
Blanco
J
J
Coello
F
F
González
H
H
Iturriaga
S
S
Maspoch
D001549:Benzamides / Q000032:analysis*; D002626:Chemistry, Pharmaceutical; D002851:Chromatography, High Pressure Liquid; D012996:Solutions; D013053:Spectrophotometry
D001549:Benzamides; D012996:Solutions; C045316:cinitapride