Time and dose-related effects of the pyrethroid fluvalinate on haemolymph carbohydrates and gut lipids of honeybees, following in vivo injection of very low doses.
The injection to emerging adult workerbees with fluvalinate doses ranging from 1 femtomol to 1 nanomol per individual resulted in a reduction of haemolymph carbohydrate concentrations, particularly at the lowest dose 1 hour after injections. At the same time, a large increase was observed for triacylglycerols and to a much lesser extent for steroids and phospholipids with 0.1 picomol per bee. By contrast, fatty acids, steroids and triacylglycerols exhibited a depress at the higher dose. Most responses were thus biphasic, showing that much attention should be paid to the effects of very low doses of pesticide.
M'Diaye
K
K
University of Avignon, France.
Bounias
M
M
D000818:Animals; D001516:Bees / Q000187:drug effects / Q000378:metabolism*; D002241:Carbohydrates / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D006458:Hemolymph / Q000187:drug effects / Q000378:metabolism*; D007306:Insecticides / Q000009:adverse effects*; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000187:drug effects; D008055:Lipids / Q000032:analysis*; D009570:Nitriles; D011722:Pyrethrins / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors
D002241:Carbohydrates; D007306:Insecticides; D008055:Lipids; D009570:Nitriles; D011722:Pyrethrins; C034227:fluvalinate