Hydroxyl free radical (.OH) formation reflected by salicylate hydroxylation and neuromelanin. In vivo markers for oxidant injury of nigral neurons.
Chiueh
C C
CC
Laboratory of Clinical Science, National Institute of Mental Health, National Institutes of Health Clinical Center 10/Rm 3D-41, Bethesda, Maryland 20892.
Murphy
D L
DL
Miyake
H
H
Lang
K
K
Tulsi
P K
PK
Huang
S J
SJ
D000818:Animals; D015415:Biomarkers; D004298:Dopamine / Q000378:metabolism; D016166:Free Radical Scavengers; D005609:Free Radicals / Q000032:analysis; D006878:Hydroxides / Q000032:analysis / Q000378:metabolism*; D017665:Hydroxyl Radical; D006900:Hydroxylation; D008543:Melanins / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism / Q000473:pathology*; D012459:Salicylates / Q000494:pharmacology*; D013378:Substantia Nigra / Q000378:metabolism / Q000473:pathology*
D015415:Biomarkers; D016166:Free Radical Scavengers; D005609:Free Radicals; D006878:Hydroxides; D008543:Melanins; D012459:Salicylates; C014121:neuromelanin; D017665:Hydroxyl Radical; D004298:Dopamine