Direct interaction of the sialic acid residue of human lutropin and chorionic gonadotropin with target cell is necessary for the full expression of their hormonal action.
Department of Biochemistry, University of Tokyo, Japan.
J
J
Amano
A
A
Kobata
D001665:Binding Sites; D006063:Chorionic Gonadotropin / Q000737:chemistry*; D000242:Cyclic AMP / Q000096:biosynthesis; D006801:Humans; D007986:Luteinizing Hormone / Q000737:chemistry*; D011134:Polysaccharides / Q000494:pharmacology; D011974:Receptors, LH / Q000737:chemistry* / Q000378:metabolism; D012794:Sialic Acids / Q000737:chemistry*; D013329:Structure-Activity Relationship
D006063:Chorionic Gonadotropin; D011134:Polysaccharides; D011974:Receptors, LH; D012794:Sialic Acids; D007986:Luteinizing Hormone; C014420:colominic acid; D000242:Cyclic AMP