Production of highly specific antibodies to 1 alpha,25-dihydroxyvitamin D3 utilizing a novel haptenic derivative having a chemical bridge at 11 alpha-position.
The production of highly specific antibodies to 1 alpha,25-dihydroxyvitamin D3 1a utilizing a novel haptenic derivative 2, which was synthesized from 11 alpha,25-dihydroxycholesterol via 21 steps, has been reported. The properties of the obtained antibodies are also described.
Kobayashi
N
N
Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.
Kitahori
J
J
Mano
H
H
Shimada
K
K
D000818:Animals; D002117:Calcitriol / Q000737:chemistry / Q000276:immunology*; D002417:Cattle; D006241:Haptens / Q000276:immunology; D011817:Rabbits / Q000276:immunology
D006241:Haptens; D002117:Calcitriol