[Protective reaction of brain cells during change in permeability of the blood-brain barrier].
General anesthesia carried out in neurosurgical operations caused liberation of neurospecific proteins into blood. High content of these antigens was maintained in biological fluids within 7 days, which occurred apparently due to activation of biosynthesis. Antibodies to the antigens were detected only within 21 days after the surgical intervention. A gross liberation of specific proteins into blood, occurring under critical conditions, appears to be a protective response of brain cells to autoimmune impairments.
A P
AP
Khokhlov
I G
IG
Fetisova
A M
AM
Podlesnyĭ
V P
VP
Chekhonin
V K
VK
Malakhovskiĭ
D000941:Antigens / Q000032:analysis / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D001812:Blood-Brain Barrier / Q000276:immunology; D001921:Brain / Q000166:cytology / Q000276:immunology*; D001932:Brain Neoplasms / Q000276:immunology* / Q000473:pathology; D006801:Humans
D000941:Antigens; D001323:Autoantibodies