Autoionization reaction of phosgene (OCCl2) studied by electron paramagnetic resonance/spin trapping techniques.
The reaction of phosgene with nitrone spin traps was investigated using electron paramagnetic resonance (EPR)/spin trapping techniques. Evidence for the intermediacy of a carbamoyl monochloride intermediate was obtained. Isotopic substitution of 13C-phosgene was employed to verify the hyperfine coupling constant assignments. The implications of these observations on pulmonary damage caused by inhalation of phosgene are mentioned.
Arroyo
C M
CM
U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5425.
Feliciano
F
F
Kolb
D L
DL
Keeler
J R
JR
Millette
S R
SR
Stotts
R R
RR
D004578:Electron Spin Resonance Spectroscopy / Q000379:methods; D005609:Free Radicals; D009589:Nitrogen Oxides / Q000737:chemistry; D010705:Phosgene / Q000737:chemistry*; D013113:Spin Labels
D005609:Free Radicals; D009589:Nitrogen Oxides; D013113:Spin Labels; D010705:Phosgene