Functional development of central nervous system in the rat: ontogeny of nociceptive thresholds.
The functional development of central nervous system (CNS) in the rat has been studied from the 10th to the 45th postnatal day, through a sensory function: nociception. Baseline pain responsiveness has been assessed with the tail-flick procedure. The mean tail-flick latency clearly decreases from the 10th to the 25th day, and remains stationary from this age to 45 days. The maturational processes underlying these reductions of tail-flick latencies in developing rats are discussed.
Département de Biologie et Physiologie animale, Faculté des Sciences et Techniques, Université Nationale, Abidjan, Côte d'Ivoire.
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D000375:Aging / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn; D002490:Central Nervous System / Q000502:physiology*; D005260:Female; D008297:Male; D009619:Nociceptors / Q000502:physiology*; D017288:Pain Threshold / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D011930:Reaction Time / Q000502:physiology; D013697:Thermosensing / Q000502:physiology