Cytomegalovirus infections of the oral cavity. A report of six cases and review of the literature.
Cytomegalovirus is responsible for a significant percentage of asymptomatic viral infections worldwide. Although virtually any cell or organ may be infected, involvement of the oral cavity is uncommon. Only nine well-documented examples of intraoral cytomegalovirus infections were found in a review of the English-language literature. We report six additional examples, five of which possessed unique clinical and histopathologic characteristics. The light and electron-microscopic features of cytomegalovirus are discussed, as well as diagnostic adjuncts such as immunohistochemistry and deoxyribonucleic acid in situ hybridization.
Department of Oral Diagnostic Sciences, University of Florida College of Dentistry, Gainesville.
A C
AC
Jones
P D
PD
Freedman
J A
JA
Phelan
R A
RA
Baughman
S M
SM
Kerpel
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D000368:Aged; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D004279:DNA, Viral / Q000032:analysis; D006679:HIV Seropositivity / Q000150:complications; D006660:Histoplasmosis / Q000150:complications; D006801:Humans; D017403:In Situ Hybridization; D007181:Inclusion Bodies, Viral; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D012514:Sarcoma, Kaposi / Q000150:complications; D013283:Stomatitis, Herpetic / Q000150:complications
D004279:DNA, Viral