[The causes of death in animals with hydrogen peroxide poisoning].
Hydrogen peroxide (HP) was administered to experimental rats at the level of LD100. The indices of external breathing, blood pressure, ECG, heart thrust were determined. It was found that the increasing tonus of the vagus nucleus was an essential feature of the pathogenesis of HP poisoning, inducing a series of pathological changes in animals. A certain role was played by extensive gas embolism. About 80% of the experimental animals survived after administration of atropine or lobeline.
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Kuznetsov
D000208:Acute Disease; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002245:Carbon Dioxide / Q000097:blood; D002423:Cause of Death; D004562:Electrocardiography / Q000187:drug effects; D006861:Hydrogen Peroxide / Q000506:poisoning*; D010100:Oxygen / Q000097:blood; D011041:Poisoning / Q000097:blood / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D051381:Rats; D012119:Respiration / Q000187:drug effects; D013318:Stroke Volume / Q000187:drug effects
D002245:Carbon Dioxide; D006861:Hydrogen Peroxide; D010100:Oxygen