Diffuse proliferative glomerulonephritis with hepatitis C virus-like particles in paramesangial dense deposits in a patient with chronic hepatitis C virus hepatitis.
A 62-year-old man with hepatitis C virus (HCV) infection developed proliferative glomerulonephritis with IgM and C3 deposits. Electron microscopy showed HCV-like particles in the paramesangial dense deposits, which are similar in shape to HCV previously described. These findings suggest HCV-related proliferative glomerulonephritis.
Department of Medicine, Juntendo University School of Medicine, Tokyo, Japan.
S
S
Horikoshi
T
T
Okada
I
I
Shirato
S
S
Inokuchi
H
H
Ohmuro
Y
Y
Tomino
H
H
Koide
D002908:Chronic Disease; D003176:Complement C3 / Q000276:immunology; D005920:Glomerular Mesangium / Q000382:microbiology* / Q000473:pathology; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D016174:Hepacivirus; D006526:Hepatitis C / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged
D003176:Complement C3; D007075:Immunoglobulin M