Malignant lymphoma of Waldeyer's ring. A histological and immunohistochemical study.
The histopathological and immunohistological features of non-Hodgkin's lymphoma limited to the Waldeyer's ring were studied in 22 Japanese patients using a panel of T- and B-cell markers on paraffin-embedded sections. All cases showed a diffuse growth pattern. Twenty cases were B-cell lymphomas and two were T-cell lymphomas. In contrast to the primary malignant lymphomas of the nasal cavity and paranasal sinuses, in which T-cell neoplasms are more frequently seen, the majority of the primary Waldeyer's ring lymphomas were B-cell neoplasms. Sixteen of the 20 cases of B-cell lymphoma were centroblastic lymphomas, and the monomorphic variant comprised the majority of these; the other three B-cell lymphomas were immunocytomas. Two of the T-cell lymphomas showed morphological features of angiocentric lymphomas.
Department of Pathology, Ashikaga Red Cross Hospital, Japan.
M
M
Kojima
Y
Y
Tamaki
S
S
Nakamura
Y
Y
Hosomura
Y
Y
Kurabayashi
H
H
Itoh
K
K
Yoshida
H
H
Niibe
T
T
Suchi
T
T
Johshita
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007128:Immunoglobulin Fragments / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D007150:Immunohistochemistry; D008223:Lymphoma / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010157:Palatal Neoplasms / Q000473:pathology* / Q000628:therapy; D010160:Palate, Soft; D011379:Prognosis; D014067:Tonsillar Neoplasms / Q000473:pathology* / Q000628:therapy
D007128:Immunoglobulin Fragments; D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains