Small cell carcinoma of the ovary with hypercalcemia responsive to sequencing chemotherapy.
Small cell carcinoma of the ovary with hypercalcemia is a rare neoplasm that has been exceedingly difficult to treat. It tends to occur in young women, and we have found no reports of survivors when this neoplasm has spread beyond the ovary. We have described a patient who has had long-term survival despite extraovarian disease. We conclude that aggressive sequencing chemotherapy followed by irradiation may be of value in treating this neoplasm.
Department of Obstetrics and Gynecology, University of Florida Health Science Center, Jacksonville 32209-6511.
G I
GI
Benrubi
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P
Pitel
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N
Lammert
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003131:Combined Modality Therapy; D004351:Drug Resistance; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis / Q000209:etiology*; D007044:Hysterectomy; D007124:Immunoenzyme Techniques; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D011379:Prognosis; D012086:Reoperation; D015996:Survival Rate; D014057:Tomography, X-Ray Computed