Two human breast tumors with translocations involving 12q13-15 as the sole cytogenetic abnormality.
Two benign epithelial breast lesions showing clonal chromosomal alterations involving 12q13-15 are reported. As the only clonal aberration a t(12;14)(q13-14;q24) was noted in a florid epithelial hyperplasia with extended adenosis. A t(10;12)(p14-15;q13) was found in a papilloma also with areas of florid epithelial hyperplasia.
Center of Human Genetics and Genetic Counseling, University of Bremen, Germany.
C
C
Rohen
U
U
Bonk
B
B
Staats
S
S
Bartnitzke
J
J
Bullerdiek
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology; D002478:Cells, Cultured; D002871:Chromosome Banding; D002879:Chromosomes, Human, Pair 10; D002881:Chromosomes, Human, Pair 12; D002883:Chromosomes, Human, Pair 14; D005260:Female; D006801:Humans; D007621:Karyotyping; D014178:Translocation, Genetic