Detection of human papillomavirus DNA in an ameloblastoma using the in situ hybridization technique.
HPV type 18 DNA was identified in an intrabony ameloblastoma using radiolabelled in situ hybridization. The viral DNA was found in a verrucous lesion in a cystic area of the tumor. The absence of HPV DNA in other epithelial areas of the ameloblastoma is suggestive of a secondary infection. HPV is not considered to be an etiological factor in the pathogenesis of this ameloblastoma.
Department of Oral Pathology and Oral Biology, Medical University of Southern Africa, Medunsa.
W F
WF
van Heerden
E J
EJ
van Rensburg
E J
EJ
Raubenheimer
E H
EH
Venter
D000328:Adult; D000564:Ameloblastoma / Q000382:microbiology* / Q000473:pathology; D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics; D004848:Epithelium / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D007642:Keratosis / Q000473:pathology; D008297:Male; D008339:Mandibular Neoplasms / Q000382:microbiology* / Q000473:pathology; D009693:Nucleic Acid Hybridization; D010212:Papilloma / Q000473:pathology; D027383:Papillomaviridae / Q000235:genetics*
D015344:DNA Probes, HPV; D004279:DNA, Viral