[Clinical experience with continuous warm blood cardioplegia].
We applied the Continuous Warm Blood Cardioplegia (CWBC) as an approach to improve myocardial preservation. From March to June in 1992, we used the CWBC in six patients and the conventional cold crystalloid cardioplegia (CCCP) in seven patients. All of them underwent isolated coronary artery bypass grafting. There was no marked difference between the CWBC and CCCP in post operative serum level of creatine kinase (MB type), cardiac output and dose of dopamine during they weaned from cardiopulmonary bypass. All patients treated with CWBC spontaneously restored the normal sinus rhythm shortly after removal of the aortic crossclamp, which was distinct from the fact that the CCCP group showed no such recovery. This result suggest that CWBC kept high-energy phosphate level without disturbing production of ATP in myocardium. Furthermore, reperfusion injury was also likely to be prevented by CWBC.
Nagata
M
M
Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, Kurume, Japan.
Tashiro
T
T
Nakamura
M
M
Tanaka
K
K
Haruta
Y
Y
Todo
K
K
D000368:Aged; D001769:Blood; D002314:Cardioplegic Solutions; D005260:Female; D006324:Heart Arrest, Induced / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control; D011188:Potassium; D017680:Potassium Compounds; D064030:S100 Calcium Binding Protein G; D013696:Temperature
D002314:Cardioplegic Solutions; D017680:Potassium Compounds; D064030:S100 Calcium Binding Protein G; C018369:potassium cardioplegic solution; D011188:Potassium