Neonatal lupus erythematosus syndrome: late detection of isolated heart block.
Heart block in neonatal lupus erythematosus is typically complete and detected in utero or in the neonatal period. We describe a child diagnosed with incomplete heart block at 9 years of age whose mother was diagnosed with Sjögren's syndrome and anti-Ro(SSA) 2 years after diagnosis of heart block in her child. This is the first case of late detection of incomplete heart block in a child felt to be causally related to the presence of anti-Ro(SSA) in the mother.
Johns Hopkins Medical Institutions, Department of Medicine (Division of Molecular and Clinical Rheumatology, Division of Cardiology), Baltimore, MD.
D P
DP
McCarron
D B
DB
Hellmann
T A
TA
Traill
R M
RM
Watson
D001324:Autoantigens / Q000032:analysis; D002648:Child; D005260:Female; D006327:Heart Block / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000151:congenital / Q000276:immunology; D008297:Male; D008431:Maternal-Fetal Exchange; D008875:Middle Aged; D011247:Pregnancy; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins / Q000032:analysis; D012859:Sjogren's Syndrome / Q000175:diagnosis / Q000276:immunology; D013997:Time Factors; D000099207:SS-A Antigen
D001324:Autoantigens; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins; D000099207:SS-A Antigen; C116006:RO60 protein, human