Effects of amphetamine on influenza virus infection in mice.
Several experiments were conducted to evaluate the effects of chronic amphetamine on the influenza A (PR-8/34) virus specific immune injury in CD-1 mice. Treatment with amphetamine resulted in a significant increase of lung virus titers and pulmonary vascular permeability. Amphetamine also increased the lethality of infected mice.
Núñez
M J
MJ
Neuroinmunología-Universidad de Santiago (NIMUS), University of Santiago de Compostela, Spain.
Fernández-Rial
J C
JC
Couceiro
J
J
Suárez
J A
JA
Gómez-Fernández
D E
DE
Rey-Méndez
M
M
Freire-Garabal
M
M
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D008168:Lung / Q000382:microbiology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009975:Orthomyxoviridae / Q000187:drug effects* / Q000472:pathogenicity; D009976:Orthomyxoviridae Infections / Q000188:drug therapy*; D011897:Random Allocation
D000661:Amphetamine