[The reaction of the hypothalamo-hypophyseal-adrenal cortex system in rats to unilateral adrenalectomy in hypoparathyroidism].
Parathyroidectomy and subsequent hypocalcemia were shown to inhibit the response of the hypothalamo-hypophyseal-adrenocortical system (HHACS) to unilateral adrenalectomy, as expressed by a lesser compensatory hypertrophy of intact adrenal gland and a lower concentration of 11-oxycorticosteroids in adrenal gland and in plasma. The greatest activity of the HHACS was revealed in 3-month old rats. The data obtained suggest an interaction between parathyroid and adrenal glands.
I A
IA
Drzhevetskaia
Z G
ZG
Surkhobi
T I
TI
Dzhandarova
D015062:11-Hydroxycorticosteroids / Q000032:analysis; D000311:Adrenal Glands / Q000737:chemistry / Q000502:physiology*; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000375:Aging / Q000502:physiology; D000818:Animals; D003346:Corticotropin-Releasing Hormone / Q000032:analysis; D007011:Hypoparathyroidism / Q000503:physiopathology* / Q000601:surgery; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D007031:Hypothalamus / Q000737:chemistry; D008297:Male; D010280:Parathyroid Glands / Q000503:physiopathology; D016105:Parathyroidectomy; D010902:Pituitary Gland / Q000737:chemistry; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D051381:Rats
D015062:11-Hydroxycorticosteroids; D000324:Adrenocorticotropic Hormone; D003346:Corticotropin-Releasing Hormone