Pulpal neuropeptidergic fibers.
A study was carried out on Met- and Leu-enkephalin, Gastrin/CCK-, SP-, CGRP-, NPY-immunoreactive fibers using paraffin sections of dental pulp taken from 8 apparently normal teeth (wisdom teeth or teeth extracted for orthodontic reasons). Within the limitations of the samples studied, dental pulp is characterized by the presence of sensory (Enkephalin-, Gastrin/CCK-immunoreactive) and pain fibers (SP-immunoreactive) and of fibers with a potent vasodilatory action (CGRP-immunoreactive) and by the absence of fibers with a vasoconstrictor action (NPY-immunoreactive).
Dental Clinic, University of Modena, Italy.
F
F
Lo Bianco
G
G
Borea
G
G
Barbolini
L
L
Lo Bianco
D000293:Adolescent; D000328:Adult; D003782:Dental Pulp / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D066298:In Vitro Techniques; D008297:Male; D009412:Nerve Fibers / Q000378:metabolism*; D009413:Nerve Fibers, Myelinated / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism*
D009479:Neuropeptides; D011956:Receptors, Cell Surface