T-cell lymphoma associated with periodontal disease and HIV infection. A case report.
A case is described of gingival non-Hodgkins lymphoma presenting in a site previously diagnosed as HIV-periodontitis. The lymphoma presented along with other signs of HIV infection and AIDS, which taken together were compatible with increased immunosuppression and reactivation of Epstein-Barr virus. The implications of these findings are discussed, and it is suggested that areas of gingiva which show rapid localised recession, associated with HIV seropositivity, should be monitored closely and considered for biopsy if abnormal signs are detected.
Department of Oral Medicine and Pathology, United Medical School, Guy's Hospital, London, UK.
G D
GD
Palmer
P R
PR
Morgan
S J
SJ
Challacombe
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000276:immunology; D005887:Gingival Neoplasms / Q000175:diagnosis / Q000209:etiology*; D005892:Gingivitis, Necrotizing Ulcerative / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000382:microbiology; D016399:Lymphoma, T-Cell / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D014412:Tumor Virus Infections / Q000209:etiology