Persistent altered mentation due to ethanol.
It has long been appreciated that the chronic abuse of alcohol may lead to a deterioration of intellect, personality, and behavior. Some of the ways in which this comes about are reasonably well established. The dementing diseases of Wernicke-Korsakoff syndrome, pellagra, the nonfamilial form of hepatocerebral degeneration, Marchiafava-Bignami disease, and alcoholic dementia and their relationships to chronic alcoholism are discussed in this article.
Department of Medicine (Neurology), Dartmouth Medical School, Hanover, New Hampshire.
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D000437:Alcoholism / Q000150:complications* / Q000523:psychology; D003072:Cognition Disorders / Q000209:etiology* / Q000523:psychology; D006801:Humans; D008108:Liver Diseases, Alcoholic; D010383:Pellagra / Q000209:etiology / Q000523:psychology; D011604:Psychoses, Alcoholic; D014899:Wernicke Encephalopathy / Q000209:etiology