[Mobile element distribution and quantitative character penetrance in the scute mutants of Drosophila melanogaster induced in the system of P-M hybrid dysgenesis].
A series of new scute mutants noted for reduction in one pair of bristles (humerals), but different penetrance with respect to this character, were induced in the system of P--M hybrid dysgenesis. In situ hybridization technique was used to determine the sites of the MEs pertaining to six families in 6 scute mutants and 18 isogenic lined derived from those. Through calculating the similarity indices, similarity with respect to the pattern of total distribution of all MEs examined was estimated for the lines. Results obtained favour the correlation between penetrance and ME localization. The "ME pattern-penetrance" dependence was verified using the isogenic lines. The matrix of similarity indices and the similarity tree were constructed for the mutant lines following comparative analysis of distribution of 132 hybridization sites. The structure of the tree gives in a number (3-4) of blocks made up by isogenic lines of different origin. The rank of stocks following merely ordering them as regards penetrance and the structure of both the tree and the matrix run together pretty well; what's more, compact blocks of labelled sites answer to the groups of stocks of close penetrance. Our results suggest that penetrance with respect to the number of numerals should directly depend on the peculiarities of ME localization in the genomes of mutant lines.
Furman
D P
DP
Rodin
S N
SN
Kozhemiakina
T A
TA
D000483:Alleles; D000818:Animals; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D016678:Genome; D017403:In Situ Hybridization; D008297:Male; D009154:Mutation
D004251:DNA Transposable Elements