Malignant mixed mullerian tumors of the fallopian tube.
Malignant mixed mullerian tumors of the female genital tract are rare and occur least commonly in the fallopian tube. A case is reported and 51 other cases in the literature are reviewed. The mean age at diagnosis is 59 years. Abdominal pain is the most common presenting complaint. A pelvic or abdominal mass is present in 75% of patients. The diagnosis is not usually established until surgery, with the most common preoperative diagnosis being ovarian malignancy. Seventy-five percent of cases had tumor extension beyond the fallopian tube at the time of surgery. Treatment has focused on surgery with postoperative radiation and/or chemotherapy. Prognosis is poor, with fewer than half of patients surviving 2 years. Recent reports suggest improved outcome with platinum-based chemotherapy but data are limited.
Weber
A M
AM
Division of Gynecologic Oncology, Hartford Hospital, Connecticut 06115.
Hewett
W F
WF
Gajewski
W H
WH
Curry
S L
SL
D000368:Aged; D016190:Carboplatin / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005185:Fallopian Tube Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D011379:Prognosis
D016190:Carboplatin