Elastin metabolism parameters in sera of patients with lung cancer.
Elastin metabolism parameters (elastin-derived peptides and elastase-like activity) were determined in sera of patients with lung cancer and in healthy controls. The concentration of elastin-derived peptides was statistically significantly elevated in the lung cancer group. There was no statistically significant difference in the serum elastase-like activity between the groups studied. These data seem to indicate an enhanced metabolism of elastin in patients with lung cancer.
Department of Biochemistry and Chemistry, Silesian Medical Academy, Katowice, Poland.
J
J
Gmiński
J
J
Mykala-Cieśla
M
M
Machalski
M
M
Drózdz
D000230:Adenocarcinoma / Q000097:blood*; D018288:Carcinoma, Small Cell / Q000097:blood*; D002294:Carcinoma, Squamous Cell / Q000097:blood*; D004549:Elastin / Q000097:blood / Q000302:isolation & purification / Q000378:metabolism*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010196:Pancreatic Elastase / Q000097:blood; D010446:Peptide Fragments / Q000097:blood
D010446:Peptide Fragments; D004549:Elastin; D010196:Pancreatic Elastase