New developments with herpesviruses and the nervous system.
Most of the human herpesviruses have a unique relationship with the central nervous system. In this review we summarize recent developments in the establishment of viral latency, and discuss the nervous system illnesses instigated by direct viral cytopathic effect, by immune activation, and by neoplastic events. Special consideration is given to herpesvirus infections in the context of acquired immunodeficiency syndrome, and in association with neonatal infections. New diagnostic techniques and treatments are also summarized.
University of Western Ontario, University Hospital, London, Canada.
F J
FJ
Picard
S D
SD
Poland
G P
GP
Rice
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D000212:Acyclovir / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D006564:Herpesviridae / Q000276:immunology; D006566:Herpesviridae Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology
D000212:Acyclovir