Prevalence of antibodies to Norwalk virus in England: detection by enzyme-linked immunosorbent assay using baculovirus-expressed Norwalk virus capsid antigen.
A total of 3,250 serum specimens collected in England in 1991 and 1992 were tested by an indirect enzyme-linked immunosorbent assay for antibody to Norwalk virus using baculovirus-expressed capsid antigen, and 2,382 (73.3%) were positive. The prevalence of Norwalk virus antibody differed regionally. It was lowest (24.6%) in 6- to 11-month-old infants and increased to 89.7% in persons over 60 years old.
Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, United Kingdom.
J J
JJ
Gray
X
X
Jiang
P
P
Morgan-Capner
U
U
Desselberger
M K
MK
Estes
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000097:blood*; D000956:Antigens, Viral / Q000276:immunology*; D016367:Baculoviridae / Q000235:genetics; D002213:Capsid / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004739:England / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009663:Norwalk virus / Q000276:immunology*; D015995:Prevalence; D011994:Recombinant Proteins / Q000276:immunology; D014777:Virus Diseases / Q000453:epidemiology*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D011994:Recombinant Proteins