Generation of humanized monoclonal antibodies by 'best fit' framework selection and recombinant polymerase chain reaction.
Lewis
A P
AP
Department of Cell Biology, Wellcome Research Laboratories, Beckenham, Kent, UK.
Crowe
J S
JS
D000818:Animals; D000911:Antibodies, Monoclonal / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D000918:Antibody Specificity; D005803:Genes, Immunoglobulin; D005813:Genes, Synthetic; D007135:Immunoglobulin Variable Region / Q000235:genetics / Q000276:immunology; D051379:Mice; D016297:Mutagenesis, Site-Directed; D016133:Polymerase Chain Reaction; D015202:Protein Engineering / Q000379:methods*; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D013698:Templates, Genetic
D000911:Antibodies, Monoclonal; D007135:Immunoglobulin Variable Region; D011993:Recombinant Fusion Proteins