Involvement of 10q22 in leiomyoma.
Cytogenetic investigation of uterine leiomyomas revealed a rearranged 10q22 present in nine tumors as a clonal change in most of the cells analyzed. These findings indicate that abnormalities involving chromosome 10 and, particularly 10q22, may characterize a cytogenetic subgroup of uterine leiomyomas.
Ozisik
Y Y
YY
Cancer Center of Southwest Biomedical Research Institute, Scottsdale, Arizona 85251.
Meloni
A M
AM
Surti
U
U
Sandberg
A A
AA
D002869:Chromosome Aberrations; D002879:Chromosomes, Human, Pair 10; D005260:Female; D006801:Humans; D007621:Karyotyping; D007889:Leiomyoma / Q000235:genetics*; D014594:Uterine Neoplasms / Q000235:genetics*