Epidermotropic metastasis coexisting with multiple primary cutaneous malignant melanomas.
A 45-year-old male, with a history of malignant melanoma on the thorax excised 4 years ago, presented a sudden eruption of more than 300 pigmented lesions. Fifteen excisions of tumors in different stages were carried out on four different dates. Dermatopathological examinations revealed features of primary as well as metastatic malignant melanomas. We suggest that besides the extensive dissemination there was also an activation of the resting melanocytes, that led to the formation of multiple primary melanomas.
Conejo-Mir
J S
JS
Medical Surgical Dermatology and Venereology Department, V. Macarena University Hospital, Faculty of Medicine, Seville, Spain.
Camacho
F
F
Ríos
J J
JJ
González-Cámpora
R
R
D004817:Epidermis / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000473:pathology* / Q000556:secondary*; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology* / Q000556:secondary*