[The prevalence of antibodies against Giardia lamblia in umbilical cord serum and in maternal peripheral blood].
Using an immunoenzymatic assay (ELISA), 40 serum samples from the peripheral blood of women in labor and serum from the umbilical cord of their offspring were analyzed in order to detect the prevalence of antibodies against Giardia lamblia. The results show that 12.5% of the maternal serum samples and 15.0% of those from the umbilical cord had optical density values comparable to those positive for G. lamblia used in the assay. This suggests that important concentrations of maternal IgG antibodies for the parasite are transferred through the placenta. The role that these antibodies play in the neonatal protection is still to be determined.
Lascurain-Ledesma
R
R
Laboratorio de Inmunoquímica y Biología Celular, Hospital Infantil de México Federico Gómez, D.F.
Mora-Jaen
M E
ME
Acosta-Altamirano
G
G
Santos-Preciado
J I
JI
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D016829:Giardia lamblia / Q000276:immunology*; D005873:Giardiasis / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007231:Infant, Newborn; D008800:Mexico / Q000453:epidemiology; D011247:Pregnancy; D015995:Prevalence; D014219:Trial of Labor
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G