Nonoperative management of post-transplantation bladder leak: serendipitous salutary effect of temporary cyclosporine nephrotoxicity and oligoanuria.
Post-transplantation bladder leak, a potentially serious complication, is traditionally managed by reexploration and closure, and may require percutaneous placement of a nephrostomy tube. We report intractable bladder leakage that persisted following reclosure in a patient who also had cyclosporine nephrotoxicity. The attendant oligoanuria obviated the need for nephrostomy drainage and allowed healing of the bladder leak. The patient subsequently recovered from cyclosporine injury and regained renal function.
Khauli
R B
RB
Department of Surgery, University of Massachusetts Medical School, Worcester 01655.
Cohen
A J
AJ
Pullman
J M
JM
Stoff
J S
JS
D000328:Adult; D001002:Anuria / Q000139:chemically induced*; D016572:Cyclosporine / Q000009:adverse effects*; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications / Q000628:therapy*; D001747:Urinary Bladder Fistula / Q000628:therapy*
D016572:Cyclosporine