title: Fatal septicemia and bullae caused by non-01 Vibrio cholerae.
abstract: Bullous lesions associated with non-01 Vibrio cholerae developed in a patient with hepatic cirrhosis who had recently ingested raw oysters. He died of overwhelming sepsis despite 5 days of aggressive antibiotic therapy. Non-01 V. cholerae was isolated from blood, peritoneal fluid, and bullae. The organism produced a cytotoxic factor that destroyed Chinese hamster ovary cells. Although septicemia caused by non-01 V. cholerae is uncommon, cutaneous manifestations of this organism are even rarer. Our patient represents the first reported case of bullous lesions associated with non-01 V. cholerae septicemia.
authors.affiliation: Department of Dermatology, University of Texas Medical Branch, Galveston 77550.
authors.forename: C
authors.initials: C
authors.lastname: Newman
authors.forename: M
authors.initials: M
authors.lastname: Shepherd
authors.forename: M D
authors.initials: MD
authors.lastname: Woodard
authors.forename: A K
authors.initials: AK
authors.lastname: Chopra
authors.forename: S K
authors.initials: SK
authors.lastname: Tyring
mesh_terms: D000818:Animals; D002771:Cholera / Q000209:etiology*; D017809:Fatal Outcome; D005517:Foodborne Diseases / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010125:Ostreidae; D018805:Sepsis / Q000209:etiology*; D012772:Shock, Septic / Q000209:etiology; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology*; D014734:Vibrio cholerae / Q000302:isolation & purification*