[Effects of combined therapy of traditional Chinese and Western medicine on C-reactive protein in post-debridement patients].
Closely monitoring whether the secondary infection in the patients of post-debridement occurred or not and appropriately treating these patients were the important ways to reduce the incidence of infection. Through estimating the level of the serum C-reactive protein (CRP) as the monitoring index of infection, dynamically observed the effect of the combined traditional Chinese and Western medicine therapy (TCM-WM) on CRP after debridement, as was compared with the effect of the Western medicine therapy (WM) group in which only the WM was administrated. The result showed that the levels of CRP decreased in both TCM-WM and WM group on 4th day after the operation, but the level of CRP in former group was lower than that in latter one, the difference was very significant (P < 0.001). So that, it was assumed that TCM-WM significantly excelled the WM on affecting the level of CRP and reducing the incidence of infection. It was suggested that CRP could be used as an effective and objective index to determine whether the secondary infection has happened and to assess the efficacy of some drugs.
Liu
B P
BP
Xiehe Hospital, Tonji Medical University, Wuhan.
Shen
L
L
Yang
J Y
JY
D000293:Adolescent; D000328:Adult; D001134:Arm Injuries / Q000097:blood / Q000601:surgery; D002097:C-Reactive Protein / Q000378:metabolism*; D003131:Combined Modality Therapy; D003646:Debridement; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007869:Leg Injuries / Q000097:blood / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010406:Penicillins / Q000627:therapeutic use*; D013530:Surgical Wound Infection / Q000097:blood* / Q000188:drug therapy
D004365:Drugs, Chinese Herbal; D010406:Penicillins; D002097:C-Reactive Protein