The activity of Krebs cycle enzymes in the visual analyzer of rats in the norm and under stress.
Higher activity of the NAD-dependent dehydrogenases of the tricarboxylic acid cycle (TAC) is observed in the optic retina, and of FAD-dependent dehydrogenases in the occipital lobes of the brain, in the visual analyzer of intact rats. The influence of stress using Desiderato's method induces a compensatory increase in the activity of succinate dehydrogenase. Acute stress induces a change in the regulation of the activity of the TAC dehydrogenases, assessed on the basis of the reaction to functional load. The animals' remaining in the dark following stress promotes the restoration of the activity of the TAC cycle to the normal level.
Lutsenko
N S
NS
Department of Biochemistry, Zaporozh'e Medical Institute.
Yakushev
V S
VS
D000818:Animals; D001923:Brain Chemistry / Q000502:physiology; D002540:Cerebral Cortex / Q000201:enzymology; D002952:Citric Acid Cycle / Q000502:physiology*; D003624:Darkness; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D007521:Isocitrate Dehydrogenase / Q000378:metabolism; D008027:Light; D008291:Malate Dehydrogenase / Q000378:metabolism; D009243:NAD / Q000378:metabolism; D009778:Occipital Lobe / Q000201:enzymology / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D012160:Retina / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D013315:Stress, Psychological / Q000201:enzymology*; D013385:Succinate Dehydrogenase / Q000378:metabolism
D009243:NAD; D005182:Flavin-Adenine Dinucleotide; D008291:Malate Dehydrogenase; D007521:Isocitrate Dehydrogenase; D013385:Succinate Dehydrogenase