Acute myopathy and neuropathy in status asthmaticus: case report and literature review.
A 38-year-old woman developed acute, severe weakness during the treatment of status asthmaticus that included high-dose intravenous corticosteroids. A muscle biopsy and EMG indicated a myopathy, and nerve conduction studies disclosed a neuropathic component. In association with corticosteroid tapering, the clinical, EMG, and nerve conduction abnormalities resolved. In some patients, intensive treatment of status asthmaticus may cause a reversible, toxic disorder of muscle and nerve.
Lacomis
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D
Department of Neurology, University of Massachusetts Medical Center, Worcester 01655.
Smith
T W
TW
Chad
D A
DA
D000208:Acute Disease; D000328:Adult; D005260:Female; D006801:Humans; D009132:Muscles / Q000473:pathology; D009135:Muscular Diseases / Q000139:chemically induced / Q000209:etiology / Q000503:physiopathology*; D009422:Nervous System Diseases / Q000139:chemically induced / Q000209:etiology / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D013224:Status Asthmaticus / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*