Gamma globulin re-treatment in Kawasaki disease.
We retrospectively reviewed the effects of intravenous gamma-globulin (IVGG) re-treatment of 13 children with Kawasaki disease and persistent or recrudescent fever. Fever and mucocutaneous inflammation resolved within 48 hours in nine patients; fever abated in two other children after a third course of IVGG. We conclude that IVGG re-treatment of Kawasaki disease appears to be safe and may improve the clinical course.
Sundel
R P
RP
Department of Medicine, Children's Hospital, Boston, Massachusetts 02115.
Burns
J C
JC
Baker
A
A
Beiser
A S
AS
Newburger
J W
JW
D002675:Child, Preschool; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000453:epidemiology / Q000628:therapy*; D012189:Retrospective Studies; D017211:Treatment Failure
D016756:Immunoglobulins, Intravenous