title: Allopurinol-induced toxic pustuloderma.
abstract: We report the case of a 67-year-old man who developed a pustular eruption, fever, neutrophilia and eosinophilia, following a short course of allopurinol. Toxic pustuloderma is an uncommon form of generalized pustular eruption with several characteristic clinical and pathological features. A number of drugs have been incriminated, but to our knowledge this is the first reported case of toxic pustuloderma occurring after the administration of allopurinol.
authors.affiliation: Unit of Dermatology, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
authors.forename: R C
authors.initials: RC
authors.lastname: Yu
authors.forename: T C
authors.initials: TC
authors.lastname: Chu
mesh_terms: D000368:Aged; D000493:Allopurinol / Q000009:adverse effects*; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology
chemical_list: D000493:Allopurinol