title: Sero-epidemiological survey of Toxoplasma gondii infection in Ethiopia.
abstract: In Ethiopia the prevalence of IgG antibodies to Toxoplasma gondii has been determined by an enzyme-linked immunosorbent assay (ELISA). One thousand and sixteen sera collected in six different geographical regions were analyzed. Antibody titres > 15 IU/ml were detected in 74.4% of the specimens, titres exceeding 200 IU/ml in one third of the ELISA-positive sera. The highest antibody titres were found in children and 75% of young adults had sero-converted. As infection with the human immunodeficiency virus 1 (HIV-1) frequently leads to a resurgence of toxoplasmosis, the diagnosis of T. gondii encephalitis should be considered in the clinical management of the HIV-immunocompromised Ethiopian patients.
authors.affiliation: Armauer Hansen Research Institute (AHRI), Addis Abeba, Ethiopia.
authors.forename: M
authors.initials: M
authors.lastname: Guebre-Xabier
authors.forename: A
authors.initials: A
authors.lastname: Nurilign
authors.forename: A
authors.initials: A
authors.lastname: Gebre-Hiwot
authors.forename: A
authors.initials: A
authors.lastname: Hailu
authors.forename: Y
authors.initials: Y
authors.lastname: Sissay
authors.forename: E
authors.initials: E
authors.lastname: Getachew
authors.forename: D
authors.initials: D
authors.lastname: Frommel
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006306:Health Surveys; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007223:Infant; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012008:Recurrence; D016036:Seroepidemiologic Studies; D014123:Toxoplasmosis / Q000097:blood / Q000150:complications / Q000453:epidemiology*
chemical_list: D007074:Immunoglobulin G