[Cardiac symptoms in 2 patients with Seckel syndrome].
Seckel's Syndrome is a rare (< 1:10,000) malformation, presumably inherited as an autosomal-recessive trait. It is characterized by failure to thrive, mental retardation, bird-like malformation of the face and further abnormalities. Cardiac anomalies have not been described so far. We report two patients with cardiac malformations, a complex defect and a patient ductus arteriosus.
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Klinik für Kinder und Jugendliche, Städtische Krankenanstalten Esslingen am Neckar.
von Brenndorff
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D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000235:genetics; D015148:Cardiotocography; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D004374:Ductus Arteriosus, Patent / Q000175:diagnosis / Q000235:genetics; D004392:Dwarfism / Q000175:diagnosis / Q000235:genetics; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000235:genetics*; D005808:Genes, Recessive; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D008831:Microcephaly / Q000175:diagnosis / Q000235:genetics*; D011247:Pregnancy; D063173:Retrognathia / Q000175:diagnosis / Q000235:genetics*; D013577:Syndrome