Superior clinical efficacy of Sinement CR 50/200 versus Sinemet 25/100 in patients with fluctuating Parkinson's disease. An open and a double-blind, double-dummy, multicenter treatment evaluation. Dutch Sinement CR Study Group.
Wolters
E C
EC
Department of Neurology, Free University Hospital, Amsterdam, The Netherlands.
Horstink
M W
MW
Roos
R A
RA
Jansen
E N
EN
D000978:Antiparkinson Agents / Q000008:administration & dosage* / Q000009:adverse effects; D002230:Carbidopa / Q000008:administration & dosage* / Q000009:adverse effects; D004185:Disability Evaluation; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage* / Q000009:adverse effects; D009069:Movement Disorders / Q000188:drug therapy; D009127:Muscle Rigidity / Q000188:drug therapy; D009460:Neurologic Examination / Q000187:drug effects*; D010300:Parkinson Disease / Q000188:drug therapy*
D000978:Antiparkinson Agents; D004338:Drug Combinations; C009265:carbidopa, levodopa drug combination; D007980:Levodopa; D002230:Carbidopa