HIV recovery from saliva before and after dental treatment: inhibitors may have critical role in viral inactivation.
Unstimulated whole saliva was collected from 21 HIV-positive men and women before and after dental treatment. The frequency of HIV detection did not increase after dental treatment. Infectious HIV was recovered from only one patient. Study findings raise the possibility that, in most cases, salivary inhibitors render the virus non-infectious.
Moore
B E
BE
Department of Microbiology, University of Texas Medical Branch, Galveston 77555-1019.
Flaitz
C M
CM
Coppenhaver
D H
DH
Nichols
M
M
Kalmaz
G D
GD
Bessman
J D
JD
Cloyd
M W
MW
Lynch
D P
DP
Prabhakar
B S
BS
Baron
S
S
D000328:Adult; D000998:Antiviral Agents; D017742:Dental Care for Chronically Ill; D005260:Female; D006678:HIV / Q000302:isolation & purification*; D016655:HIV Core Protein p24 / Q000302:isolation & purification; D015658:HIV Infections / Q000635:transmission*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000502:physiology; D006472:Oral Hemorrhage; D012463:Saliva / Q000382:microbiology*; D012471:Salivary Proteins and Peptides / Q000502:physiology*
D000998:Antiviral Agents; D016655:HIV Core Protein p24; D009077:Mucins; D012471:Salivary Proteins and Peptides