Allopurinol-induced toxic pustuloderma.
We report the case of a 67-year-old man who developed a pustular eruption, fever, neutrophilia and eosinophilia, following a short course of allopurinol. Toxic pustuloderma is an uncommon form of generalized pustular eruption with several characteristic clinical and pathological features. A number of drugs have been incriminated, but to our knowledge this is the first reported case of toxic pustuloderma occurring after the administration of allopurinol.
Yu
R C
RC
Unit of Dermatology, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
Chu
T C
TC
D000368:Aged; D000493:Allopurinol / Q000009:adverse effects*; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology
D000493:Allopurinol