Sickle cell anemia is a multigene disease: sickle painful crises, a case in point.
Nagel
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Division of Hematology, Albert Einstein College of Medicine, Bronx, New York 10461.
D000755:Anemia, Sickle Cell / Q000235:genetics* / Q000473:pathology; D002880:Chromosomes, Human, Pair 11; D004843:Epistasis, Genetic; D005796:Genes; D006801:Humans; D008957:Models, Genetic; D010146:Pain