title: Update: availability of sulfadiazine--United States.
abstract: Sulfadiazine is a sulfa drug commonly used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome (AIDS) and newborns with congenital infections. In December 1992, CDC reported that the domestic manufacturer of sulfadiazine had ceased production in October 1992 and that no large inventories of the drug were available from major distributors (1). On February 8, CDC obtained permission from the Food and Drug Administration (FDA) to proceed with an "Investigational New Drug" (IND) application protocol under which sulfadiazine may be imported and made available to physicians until a domestic commercial source is re-established.
mesh_terms: D015507:Drugs, Investigational / Q000600:supply & distribution; D013411:Sulfadiazine / Q000600:supply & distribution*; D014481:United States
chemical_list: D015507:Drugs, Investigational; D013411:Sulfadiazine