MR microscopy of the rat lung using projection reconstruction.
Projection reconstruction has been implemented with self-refocused selection pulses on a small bore, 2.0 T MR microscope, to allow imaging of lung parenchyma. Scan synchronous ventilation and cardiac gating have been integrated with the sequence to minimize motion artifacts. A systematic survey of the pulse sequence parameters has been undertaken in conjunction with the biological gating parameters to optimize resolution and signal-to-noise (SNR). The resulting projection images with effective echo time of < 300 microseconds allow definition of lung parenchyma with an SNR improvement of approximately 15 x over a more conventional 2DFT short echo gradient sequence.
Gewalt
S L
SL
Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
Glover
G H
GH
Hedlund
L W
LW
Cofer
G P
GP
MacFall
J R
JR
Johnson
G A
GA
D000818:Animals; D005260:Female; D008168:Lung / Q000166:cytology*; D008279:Magnetic Resonance Imaging; D008853:Microscopy; D051381:Rats; D017207:Rats, Sprague-Dawley