title: Endogenous susceptibility contrast in myocardium during apnea measured using gradient recalled echo planar imaging.
abstract: Gradient recalled echo planar imaging was used to monitor changes in myocardial and left ventricular chamber blood intensity during apnea in rats. Significant signal loss in both blood (to 62 +/- 5% and 51 +/- 6% of baseline) and myocardium (to 79 +/- 2% and 76 +/- 3% of baseline) was observed at 45 and 90 s apnea while O2 saturation decreased from 98 +/- 1% to 62 +/- 7% and 36 +/- 9%, respectively. These results show that myocardial intensity is modulated by alterations in blood oxygenation.
authors.affiliation: Department of Radiology, University of California, San Francisco 94143.
authors.forename: M F
authors.initials: MF
authors.lastname: Wendland
authors.forename: M
authors.initials: M
authors.lastname: Saeed
authors.forename: K
authors.initials: K
authors.lastname: Lauerma
authors.forename: A
authors.initials: A
authors.lastname: de Crespigny
authors.forename: M E
authors.initials: ME
authors.lastname: Moseley
authors.forename: C B
authors.initials: CB
authors.lastname: Higgins
mesh_terms: D000818:Animals; D001049:Apnea / Q000175:diagnosis*; D017352:Echo-Planar Imaging / Q000379:methods*; D006454:Hemoglobins / Q000378:metabolism; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*; D010100:Oxygen / Q000097:blood; D051381:Rats; D017207:Rats, Sprague-Dawley; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D006454:Hemoglobins; C100003:deoxyhemoglobin; D010100:Oxygen