The gamma fibrinogen gene (FGG) maps to chromosome 17 in both cattle and sheep.
The gamma fibrinogen gene (FGG) was localised in both cattle and sheep using in situ hybridisation. The probe employed was a 1-kb bovine cDNA fragment. Based on observations of QFQ-banded chromosome preparations, this locus is on bovine chromosome 17q12-->q13 and on the homologous sheep chromosome 17. This localisation is, to our knowledge, the first assignment to chromosome 17 in either the bovine or ovine genome. In addition to localising FGG to this chromosome, the assignment provisionally maps the previously unassigned syntenic group U23, containing (besides FGG) the genes for mitochondrial aldehyde dehydrogenase 2 (ALDH2), interleukin 2 (IL2), immunoglobulin lambda (IGL), and beta fibrinogen (FGB), to chromosome 17 in cattle and probably to the same chromosome in sheep.
Johnson
S E
SE
CSIRO, Division of Tropical Animal Production, University of Queensland, Australia.
Barendse
W
W
Hetzel
D J
DJ
D000818:Animals; D002417:Cattle / Q000235:genetics*; D002874:Chromosome Mapping; D002875:Chromosomes; D004247:DNA / Q000032:analysis; D015342:DNA Probes; D005340:Fibrinogen / Q000235:genetics*; D005347:Fibroblasts / Q000166:cytology; D017403:In Situ Hybridization; D012689:Sequence Homology, Nucleic Acid; D012756:Sheep / Q000235:genetics*
D015342:DNA Probes; D005340:Fibrinogen; D004247:DNA