title: Isolation and characterization of seven lyso platelet-activating factors and two lyso phosphatidylcholines from the crude drug "suitetsu" (the leech, Hirudo nipponica).
abstract: Nine lyso glycerophospholipids were isolated in the pure state from the crude drug "Suitetsu", which is the dried body of the leech, Hirudo nipponica (Hirudidae). They were identified as 1-O-hexadecyl-(1), 1-O-octadecyl-(2), 1-O-tetradecyl-(3), 1-O-9-cis-hexadecenyl-(4), 1-O-hexadecanoyl-(5), 1-O-pentadecyl-(6), 1-O-15-methylhexadecyl-(7), 1-O-octadecanoyl-(8) and 1-O-heptadecyl-sn-glycero-3-phosphocholine (9). Two of them (5 and 8) are lysophosphatidylcholines and the other seven are lyso platelet-activating factors. One of them has an alkenyl carbon chain.
authors.affiliation: Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Noda
authors.forename: R
authors.initials: R
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Nishi
authors.forename: S
authors.initials: S
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Miyahara
mesh_terms: D000818:Animals; D002855:Chromatography, Thin Layer; D007865:Leeches / Q000378:metabolism*; D008244:Lysophosphatidylcholines / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D010972:Platelet Activating Factor / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D008244:Lysophosphatidylcholines; D010972:Platelet Activating Factor