title: [Significance of historical and current hallucinogenic research in psychiatry].
abstract: Research in experimental psychosis has a long tradition extending through several stages. With the world wide abuse of psychoactive substances it came to an abrupt end. Systematic questions within this framework of research are still unresolved, and research on newly developed compounds is almost completely lacking. A review of the pharmacological and psychological effects of various psychoactive agents is provided, and results of recent experimental studies on arylalkylamines are discussed. It is argued that from a systematic as well as from a methodological viewpoint the traditional approach of experimental psychosis represents a valuable tool in psychiatric research.
authors.affiliation: Fachkrankenhaus für Psychiatrie und Neurologie, Christophsbad, Göppingen.
authors.forename: L
authors.initials: L
authors.lastname: Hermle
authors.forename: E
authors.initials: E
authors.lastname: Gouzoulis
authors.forename: G
authors.initials: G
authors.lastname: Oepen
authors.forename: M
authors.initials: M
authors.lastname: Spitzer
authors.forename: K A
authors.initials: KA
authors.lastname: Kovar
authors.forename: D
authors.initials: D
authors.lastname: Borchardt
authors.forename: M
authors.initials: M
authors.lastname: Fünfgeld
authors.forename: M
authors.initials: M
authors.lastname: Berger
mesh_terms: D015104:3,4-Methylenedioxyamphetamine / Q000031:analogs & derivatives; D000328:Adult; D001143:Arousal / Q000187:drug effects; D015198:Designer Drugs; D004305:Dose-Response Relationship, Drug; D005544:Forecasting; D006212:Hallucinations / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D006213:Hallucinogens / Q000737:chemistry / Q000145:classification; D006801:Humans; D008635:Mescaline; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011605:Psychoses, Substance-Induced / Q000209:etiology*
chemical_list: D015198:Designer Drugs; D006213:Hallucinogens; D015104:3,4-Methylenedioxyamphetamine; C051800:3,4-methylenedioxyethamphetamine; D008635:Mescaline