title: Generalized melanosis associated with malignant melanoma: unusual histologic appearance.
abstract: A case of generalized melanosis associated with malignant melanoma, characterized by up-to-date, previously undescribed histologic findings, is reported. Markedly dilated dermal lymphatics with features resembling secondary lymphangioma were found. We speculate that a further mechanism, as well as those previously reported in the literature, could be operative in the pathogenesis of this disorder of altered pigmentation.
authors.affiliation: Department of Dermatology, Hospital of Brescia, Italy.
authors.forename: A M
authors.initials: AM
authors.lastname: Manganoni
authors.forename: F
authors.initials: F
authors.lastname: Facchetti
authors.forename: A
authors.initials: A
authors.lastname: Lonati
authors.forename: P
authors.initials: P
authors.lastname: Calzavara
authors.forename: G
authors.initials: G
authors.lastname: De Panfilis
mesh_terms: D000368:Aged; D004817:Epidermis / Q000473:pathology; D006801:Humans; D008202:Lymphangioma / Q000473:pathology; D008264:Macrophages / Q000473:pathology; D008297:Male; D008543:Melanins; D008545:Melanoma / Q000473:pathology*; D008548:Melanosis / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*
chemical_list: D008543:Melanins