Identification of false-positive CK-MB activity in an elderly patient.
An unusual occurrence of an aberrant CK-MB activity in an elderly female patient is described. The CK-MB-like activity present in serum samples from this patient was definitively identified as an immunoglobulin A complex of CK-MM (macro CK, type 1) using CK isoenzyme agarose gel electrophoresis after pretreating the patient's serum sample with either anti-immunoglobulin A antiserum or anti-CK-M antibody reagent.
Murthy
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Department of Laboratory Medicine, Albert Einstein College of Medicine, Bronx, New York.
D000368:Aged; D000369:Aged, 80 and over; D001797:Blood Protein Electrophoresis; D003402:Creatine Kinase / Q000097:blood*; D004587:Electrophoresis, Agar Gel; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007527:Isoenzymes
D007070:Immunoglobulin A; D007527:Isoenzymes; D003402:Creatine Kinase