title: Acute myelomonocytic leukemia in a XYY man.
abstract: A case of acute myeloid leukemia (M4) in a 29-year-old male with a 47,XYY karyotype is reported. This aneuploidy was found in both bone marrow cells and mitogen-stimulated lymphocytes. Monosomy 7 correlated with myelodysplastic features. The possible role of XYY in increasing the risk of leukemia is discussed.
authors.affiliation: Department of Hematology, Hôtel-Dieu, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Bauduer
authors.forename: S
authors.initials: S
authors.lastname: Ramond
authors.forename: A
authors.initials: A
authors.lastname: Delmer
authors.forename: B
authors.initials: B
authors.lastname: Delmas-Marsalet
authors.forename: F
authors.initials: F
authors.lastname: Viguié
authors.forename: J P
authors.initials: JP
authors.lastname: Dadoune
authors.forename: R
authors.initials: R
authors.lastname: Zittoun
mesh_terms: D000328:Adult; D005602:France; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D011174:Portugal / Q000208:ethnology; D014997:XYY Karyotype