Vasculitis presenting as primary leptomeningeal enhancement with minimal parenchymal findings.
In this case of biopsy-proved granulomatous angiitis, MR showed prominent leptomeningeal enhancement with comparatively little parenchymal involvement. Pathologically, granulomatous angiitis chiefly affects small vessels, with a predilection for those in the leptomeninges. Although marked leptomeningeal enhancement is not the most common finding, vasculitis should be added to the differential diagnosis of this MR appearance.
Negishi
C
C
Department of Diagnostic Radiology, School of Medicine, Yale University, New Haven, CT 06510.
Sze
G
G
D001921:Brain / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000175:diagnosis*; D005260:Female; D006099:Granuloma / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008578:Meninges / Q000473:pathology*; D008875:Middle Aged; D014657:Vasculitis / Q000175:diagnosis*