title: Argyrophilic neuroendocrine carcinoma of the male breast.
abstract: A case of breast carcinoma with neuroendocrine features occurring in an elderly male patient is reported. Histologically, the tumor was characterized by solid growth with nests and ribbons of small to medium-size uniform neoplastic cells. Argyrophilia, expression of chromogranins at both protein and gene level, and the presence of dense granules of the neurosecretory type by electron microscopy were demonstrated.
authors.affiliation: Department of Human Oncology, University of Turin, Torino, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Papotti
authors.forename: F
authors.initials: F
authors.lastname: Tanda
authors.forename: G
authors.initials: G
authors.lastname: Bussolati
authors.forename: F
authors.initials: F
authors.lastname: Pugno
authors.forename: L
authors.initials: L
authors.lastname: Bosincu
authors.forename: G
authors.initials: G
authors.lastname: Massareli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology*; D002276:Carcinoid Tumor / Q000737:chemistry / Q000473:pathology*; D002277:Carcinoma / Q000737:chemistry / Q000473:pathology*; D002864:Chromogranins / Q000032:analysis; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D010751:Phosphopyruvate Hydratase / Q000032:analysis
chemical_list: D002864:Chromogranins; D010751:Phosphopyruvate Hydratase