Intussusception and leiomyosarcoma of the gastrointestinal tract in a pediatric patient. Case report and review of the literature.
Intestinal leiomyosarcoma is a rare tumor in infants and children; only 46 cases have been reported in the English literature. Presenting signs and symptoms include abdominal pain and gastrointestinal obstruction and bleeding. We describe a neonate with the unique presentation of ileocecal intussusception accompanying an ileal leiomyosarcoma. In contrast to adult patients, where intussusception is associated with smooth muscle tumors in 30% of cases, leiomyosarcoma and subsequent intussusception is rare in infancy and childhood. The overall prognosis for long-term survival is similar for both pediatric and adult patients with leiomyosarcoma of the intestinal tract, with a five-year survival in reported cases of 53% and 40%, respectively.
Furuta
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Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Boston 02114.
Bross
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Doody
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Kleinman
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D006801:Humans; D007077:Ileal Diseases / Q000209:etiology; D007078:Ileal Neoplasms / Q000150:complications / Q000453:epidemiology; D007080:Ileocecal Valve; D007223:Infant; D007443:Intussusception / Q000209:etiology*; D007890:Leiomyosarcoma / Q000150:complications / Q000453:epidemiology; D008297:Male