Risks and benefits of femoropopliteal percutaneous balloon angioplasty.
OBJECTIVE
The purpose of this study was to evaluate the efficacy of angioplasty in the treatment of femoropopliteal arterial disease.


METHODS
From 1980 to 1991, 126 angioplasty procedures were performed in 131 limbs of 106 patients with 175 femoropopliteal lesions (26 common femoral, 118 superficial femoral, and 31 popliteal). Critical ischemia was present in 55 limbs (42%), and claudication was present in 76 (58%). Angioplasty was performed for a single lesion in 87 limbs (66%) and for multiple lesions in 44 (34%). In 13 limbs (10%) the most severe lesion was an occlusion; in 118 (90%) all lesions were stenoses. Distal runoff was good (2 or 3 vessels patent) in 72 limbs (55%) and poor (0 or 1 vessel patent) in 59 (45%).


RESULTS
Death within 30 days occurred in 0.8%, nonfatal systemic morbidity in 7.1%, and local morbidity in 1.6% of procedures. Multivariate analysis revealed that indication and age were predictive of increased morbidity and mortality rates. Immediate success was achieved in 95% of limbs treated. Mean follow-up time was 2.0 years. The overall 5-year cumulative primary patency rate was 45% (+/- 5%). In a proportional hazards model indication and lesion type were predictive (p < 0.01) of long-term failure, with relative risks of 2.0 (1.2 to 3.3) and 2.7 (1.3 to 5.6), respectively. The 5-year primary patency rate after angioplasty for stenoses and claudication was 55% (+/- 7%), for stenoses and critical ischemia it was 29% (+/- 11%), and for occlusions it was 36% (+/- 14%).


CONCLUSIONS
These results suggest that femoropopliteal angioplasty is a low-risk procedure with acceptable long-term results in patients with claudication and stenoses.
Hunink
M G
MG
Division of Cardiovascular and Interventional Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
Donaldson
M C
MC
Meyerovitz
M F
MF
Polak
J F
JF
Whittemore
A D
AD
Kandarpa
K
K
Grassi
C J
CJ
Aruny
J
J
Harrington
D P
DP
Mannick
J A
JA
D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D005263:Femoral Artery / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D007383:Intermittent Claudication / Q000453:epidemiology / Q000628:therapy; D007511:Ischemia / Q000453:epidemiology / Q000628:therapy; D007866:Leg / Q000098:blood supply; D015993:Life Tables; D016015:Logistic Models; D016017:Odds Ratio; D011150:Popliteal Artery / Q000000981:diagnostic imaging; D011446:Prospective Studies; D015641:Radiography, Interventional / Q000706:statistics & numerical data; D012307:Risk Factors; D014654:Vascular Patency