title: Endocarditis in neonatal intensive care unit.
abstract: The clinical spectrum of infective endocarditis (IE) in infants is examined in four infants between 3 and 9 months of age. None of the patients had signs of IE; all four had an anatomically normal heart. Echocardiograms showed echo-dense vegetations in the left side of heart in three cases and in the right side in one. Three of the four patients recovered after the episode of endocarditis. Three of the four patients had necrotizing enterocolitis in the neonatal period. The important predisposing factor was the presence of indwelling central catheter for intravenous nutrition. Unlike previously reported cases, coagulase-negative Staphylococci and Enterococci were important causative organisms in this high-risk nursery population.
authors.affiliation: Department of Pediatrics, Cook County Hospital, University of Illinois College of Medicine 60612.
authors.forename: A
authors.initials: A
authors.lastname: Rastogi
authors.forename: J A
authors.initials: JA
authors.lastname: Luken
authors.forename: R S
authors.initials: RS
authors.lastname: Pildes
authors.forename: D
authors.initials: D
authors.lastname: Chrystof
authors.forename: F
authors.initials: F
authors.lastname: LaBranche
mesh_terms: D002405:Catheterization, Central Venous / Q000295:instrumentation; D003428:Cross Infection / Q000000981:diagnostic imaging / Q000209:etiology*; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000209:etiology*; D004756:Enterobacteriaceae Infections / Q000000981:diagnostic imaging / Q000209:etiology; D004761:Enterocolitis, Pseudomembranous / Q000601:surgery; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D007363:Intensive Care Units, Neonatal; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000209:etiology