Cutaneous vasculitis and IgA glomerulonephritis in ankylosing spondylitis.
Two patients with ankylosing spondylitis were found to have IgA nephropathy and leucocytoclastic cutaneous vasculitis. Immunofluorescence showed perivascular deposition of IgA in the skin of one patient and in the mesangium of both patients. Such an association has been reported only once before. This supports the concept of abnormal IgA immune stimulation in the pathogenesis of ankylosing spondylitis.
Beauvais
C
C
Department of Rheumatology, Hôpital Saint Antoine, Paris, France.
Kaplan
G
G
Mougenot
B
B
Michel
C
C
Marinho
E
E
D005922:Glomerulonephritis, IGA / Q000209:etiology*; D006801:Humans; D011695:IgA Vasculitis / Q000209:etiology* / Q000276:immunology; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000276:immunology; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000276:immunology
D007070:Immunoglobulin A