Kallmann's syndrome: pregnancy achieved through gamete intrafallopian transfer.
This case report describes the use of GIFT to achieve pregnancy for a man with Kallmann's syndrome who obtained only marginal sperm counts with both the pulsatile GnRH infusion pump and gonadotropin injections. Failure of this man to achieve a pregnancy with hormonal therapy alone and in combination with IUI suggests that assisted reproductive technologies should be considered in male patients with Kallmann's syndrome when suboptimal sperm concentrations are achieved despite exogenous hormonal stimulation.
Smith
Y R
YR
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor.
Ansbacher
R
R
Christman
G M
GM
Hurd
W W
WW
Randolph
J F
JF
D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D005260:Female; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D007317:Insemination, Artificial, Homologous; D017436:Kallmann Syndrome / Q000150:complications*; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D011247:Pregnancy; D013480:Superovulation
D006063:Chorionic Gonadotropin; D008596:Menotropins