title: Outpatient management with oral corticosteroid therapy for obstructive conditions in chronic granulomatous disease.
abstract: We report the outpatient management of three patients with X-linked chronic granulomatous disease, two of whom had episodes of gastric outlet obstruction and another, urinary bladder obstruction. These obstructive conditions were successfully treated with 2-week courses of orally administered corticosteroids with or without the addition of orally administered clindamycin. There were no infectious or other adverse reactions.
authors.affiliation: Division of Allergy, Immunology, and Infectious Diseases, Children's Hospital of Philadelphia, PA 19104-4399.
authors.forename: R N
authors.initials: RN
authors.lastname: Danziger
authors.forename: A T
authors.initials: AT
authors.lastname: Goren
authors.forename: J
authors.initials: J
authors.lastname: Becker
authors.forename: J M
authors.initials: JM
authors.lastname: Greene
authors.forename: S D
authors.initials: SD
authors.lastname: Douglas
mesh_terms: D000284:Administration, Oral; D000553:Ambulatory Care; D002648:Child; D002981:Clindamycin / Q000008:administration & dosage / Q000627:therapeutic use; D017219:Gastric Outlet Obstruction / Q000188:drug therapy*; D006105:Granulomatous Disease, Chronic / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D001748:Urinary Bladder Neck Obstruction / Q000188:drug therapy*
chemical_list: D002981:Clindamycin; D011241:Prednisone