Transgenesis in nonmurine species.
Although the mouse remains the species of choice for most transgenic experimentation, it may be preferable or even necessary to use alternative species for certain applications. We review the strategies by which transgenic technology has been applied to other animals, specifically, the rat, rabbit, pig, sheep, goat, and cow. Additionally, we outline the potential applications of alternative transgenic species with reference to the field of hypertension and cardiovascular research.
Mullins
J J
JJ
AFRC Centre for Genome Research, University of Edinburgh, UK.
Mullins
L J
LJ
D000818:Animals; D000829:Animals, Domestic; D030801:Animals, Genetically Modified; D002417:Cattle; D005260:Female; D005818:Genetic Engineering / Q000379:methods*; D006041:Goats; D011817:Rabbits; D051381:Rats; D012418:Ruminants; D012756:Sheep; D013552:Swine