Simultaneous randomization of antibody CDRs by a synthetic ligase chain reaction strategy.
Deng
S J
SJ
Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario.
MacKenzie
C R
CR
Narang
S A
SA
D000595:Amino Acid Sequence; D000907:Antibodies, Bacterial / Q000235:genetics; D000916:Antibody Diversity / Q000235:genetics; D001483:Base Sequence; D004247:DNA; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D008025:Ligases / Q000378:metabolism*; D008969:Molecular Sequence Data; D019081:O Antigens; D011105:Polyisoprenyl Phosphate Sugars / Q000276:immunology
D000907:Antibodies, Bacterial; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D019081:O Antigens; C062656:O-specific polysaccharide, Salmonella; D011105:Polyisoprenyl Phosphate Sugars; D004247:DNA; D008025:Ligases