title: [Long-term efficacy of endovascular embolization with silk particles and their effects on surrounding tissues in rabbits].
abstract: Long-term efficacy of therapeutic embolization with silk particles in rabbits was observed. The effectiveness of embolization and their histotoxicity on surrounding tissues were compared with dry dura mater particles, polyvinyl alcohol foam (i.e. Ivalon) and isobutyl 1-2-cyanoacrylate (IBCA). The results showed that the endovascular embolization with silk particles was almost as effective as that with IBCA and superior to dry dura mater particles or Ivalon. The toxicity of silk particles was similar to Ivaion, but less than IBCA and dry dura mater particles. The authors considered that silk particles are a good embolic agent at present.
authors.affiliation: Wuhan General Hospital, Guangzhou Unit, People's liberation Army.
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Wu
mesh_terms: D000818:Animals; D002015:Bucrylate; D017536:Carotid Artery, Common / Q000473:pathology* / Q000648:ultrastructure; D004388:Dura Mater; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D008297:Male; D008863:Microspheres; D011145:Polyvinyls; D011817:Rabbits; D013784:Textiles
chemical_list: D011145:Polyvinyls; C026699:ivalon sponge; D002015:Bucrylate