N-(carboxymethyl)-N-[3,5-bis(decyloxy)-phenyl]glycine (Ro 23-9358): a potent inhibitor of secretory phospholipases A2 with antiinflammatory activity.
LeMahieu
R A
RA
Roche Research Center, Nutley, New Jersey 07110.
Carson
M
M
Han
R J
RJ
Madison
V S
VS
Hope
W C
WC
Chen
T
T
Morgan
D W
DW
Hendrickson
H S
HS
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology*; D001665:Binding Sites; D003998:Dicarboxylic Acids / Q000737:chemistry / Q000494:pharmacology*; D005998:Glycine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D010741:Phospholipases A / Q000037:antagonists & inhibitors* / Q000737:chemistry
D000894:Anti-Inflammatory Agents, Non-Steroidal; D003998:Dicarboxylic Acids; C083630:N-(carboxymethyl)-N-(3,5-bis(decyloxy)-phenyl)glycine; D010741:Phospholipases A; D005998:Glycine