title: Urogenital malacoplakia treated with fluoroquinolones.
abstract: We report 2 cases of urogenital malacoplakia and discuss the problems associated with diagnosing and treating this rare disease. In 1 case extensive pelvic disease was successfully controlled with ciprofloxacin. In the other case the malacoplakia was localized in the distal ureter and was initially mistaken for urothelial carcinoma. Nephrectomy was performed due to persistent ureteral obstruction and renal dysfunction. In the management of urogenital malacoplakia it seems essential that urinary tract infections be effectively treated. The new fluoroquinolones appear to be potentially successful in managing this disorder due to their high uptake of macrophages.
authors.affiliation: Department of Urology, State University Leiden, The Netherlands.
authors.forename: G R
authors.initials: GR
authors.lastname: Dohle
authors.forename: J
authors.initials: J
authors.lastname: Zwartendijk
authors.forename: J H
authors.initials: JH
authors.lastname: Van Krieken
mesh_terms: D002939:Ciprofloxacin / Q000627:therapeutic use*; D005260:Female; D052776:Female Urogenital Diseases / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008287:Malacoplakia / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged
chemical_list: D002939:Ciprofloxacin