Screening of esophageal and gastric cancer by occult blood bead detector.
A previously described bead method used to detect blood is simple, cheap, and effective; it can be repeated periodically. In 11 provinces in China, 233,825 persons (age range, 30-70 years) were screened. A positive occult blood test result was found in 28,557 persons (12%). Of these, 16,918 underwent a gastroscopy, resulting in the detection of 581 cancers that were located in similar frequencies in the esophagus, gastric cardia, and gastric body; 70% of the lesions were in an early or moderately advanced stage. Among 119 patients with early-stage cancer, the 3-year survival rate was 98.3%. After preliminary screening of cancer, the 4-year follow-up found a mortality rate in the group with negative occult blood test results that was only 25% of that of the positive group. Preliminary yearly screening would detect more early cancers and fewer advanced cancers. The mortality rate of esophageal and gastric cancer might be reduced drastically.
Qin
D X
DX
Department of Cancer Prevention and Detection, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing.
Wang
G Q
GQ
Zuo
J H
JH
Zhang
X H
XH
Yuan
F L
FL
Li
M S
MS
Wu
C R
CR
Ju
C L
CL
D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D004938:Esophageal Neoplasms / Q000401:mortality / Q000517:prevention & control*; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000295:instrumentation*; D008875:Middle Aged; D009780:Occult Blood; D013274:Stomach Neoplasms / Q000401:mortality / Q000517:prevention & control*; D015996:Survival Rate