title: Magnetization transfer imaging of the abdomen at 0.1 T: detection of hepatic neoplasms.
abstract: Magnetization transfer (MT) techniques have been proposed as a method of increasing contrast in MR images. To evaluate the feasibility of MT imaging of the abdomen at 0.1 T and to assess the clinical utility of this technique, the authors studied tissue contrast with a gradient-echo pulse sequence and an MT sequence in four normal volunteers, and in 17 patients with known primary or secondary neoplasms of the liver. The MT technique increased contrast between the liver and other tissues such as spleen, skeletal muscle and subcutaneous fat. The technique also produced increased contrast between hepatic tumors and normal liver parenchyma in gradient-echo images.
authors.affiliation: Department of Radiology, University of Chicago, IL 60637.
authors.forename: C E
authors.initials: CE
authors.lastname: Kahn
authors.forename: S D
authors.initials: SD
authors.lastname: Perera
authors.forename: R E
authors.initials: RE
authors.lastname: Sepponen
authors.forename: J I
authors.initials: JI
authors.lastname: Tanttu
authors.forename: E K
authors.initials: EK
authors.lastname: Tierala
authors.forename: M J
authors.initials: MJ
authors.lastname: Lipton
mesh_terms: D000005:Abdomen / Q000473:pathology*; D005240:Feasibility Studies; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods*; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D013997:Time Factors