title: [Quantitative assessment of the effect of nitroglycerin on left ventricular function with two-dimensional echocardiography in patients with myocardial infarction].
abstract: The effect of sublingual and intravenous nitroglycerin (SLNTG and IVNTG) on left ventricular global and segmental systolic function was quantitatively assessed with two-dimensional echocardiography (2DE) in 28 cases of myocardial infarction (MI), including a group without heart failure of 13 and another group with heart failure of 15. The results showed that after SLNTG and IVNTG the left ventricular end-diastolic and end-systolic volumes were significantly decreased in both groups (P < 0.05-0.001), the left ventricular global systolic function was improved particularly in MI patients with heart failure during IVNTG. The wall motion in the normal and/or hypokinetic segments was enhanced after both SLNTG and IVNTG. It was shown that nitroglycerin could strengthen the left ventricular global systolic function in patients with MI.
authors.affiliation: Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Yang
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Chen
authors.forename: Y S
authors.initials: YS
authors.lastname: Xu
mesh_terms: D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000503:physiopathology*; D005996:Nitroglycerin / Q000494:pharmacology* / Q000627:therapeutic use; D016277:Ventricular Function, Left / Q000187:drug effects*
chemical_list: D005996:Nitroglycerin