Measurement of total and unilateral renal blood flow by oblique-angle velocity-encoded 2D-cine magnetic resonance angiography.
Two independent measurements of total renal blood flow (RBF) were made in healthy human subjects (n = 14, mean age 30 yr) by CINE phase-contrast magnetic resonance angiography. RBF, measured by summing the flows measured in the right and left renal arteries, was 1152 +/- 44 ml/min (mean +/- SE). RBF, measured from the difference between supra- and infrarenal abdominal aorta flow, was 1109 +/- 68 ml/min. Regression analysis of the comparison of these two different RBF calculations yielded a correlation coefficient of 0.72 at a p < .05 level of significance. Based on other studies of RBF in normal subjects by para-aminohippuric acid (PAH) clearance, the expected RBF in this subject group was 1211 +/- 62 ml/min. The results indicate that noninvasive measurement of RBF is possible using phase-contrast magnetic resonance methods.
Lundin
B
B
Department of Radiology, Michigan State University, East Lansing 48824.
Cooper
T G
TG
Meyer
R A
RA
Potchen
E J
EJ
D000293:Adolescent; D000328:Adult; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009040:Motion Pictures / Q000295:instrumentation / Q000706:statistics & numerical data; D015588:Observer Variation; D012016:Reference Values; D012044:Regression Analysis; D012077:Renal Artery / Q000033:anatomy & histology*; D012079:Renal Circulation; D012082:Renal Veins / Q000033:anatomy & histology*