title: Bullous amyloidosis. Report of 3 cases and review of the literature.
abstract: We report 3 cases of bullous immunoglobulinic amyloidosis and review 25 published cases. In 2 of our patients, amyloid deposits were not detected with special staining, but by means of ultrastructural methods. Investigations of the skin lesions permitted the diagnosis of associated plasma cell dyscrasia in 2 patients. Unexplained bullous lesions should be investigated for amyloid deposits and the presence of monoclonal gammopathy by methods including electron microscopy and immunochemical analysis of serum and urine.
authors.affiliation: Clinique des Maladies Cutanées, Hôpital Saint-Louis, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Robert
authors.forename: S
authors.initials: S
authors.lastname: Aractingi
authors.forename: C
authors.initials: C
authors.lastname: Prost
authors.forename: O
authors.initials: O
authors.lastname: Verola
authors.forename: C
authors.initials: C
authors.lastname: Blanchet-Bardon
authors.forename: F
authors.initials: F
authors.lastname: Blanc
authors.forename: M
authors.initials: M
authors.lastname: Bagot
authors.forename: L
authors.initials: L
authors.lastname: Dubertret
authors.forename: J P
authors.initials: JP
authors.lastname: Fermand
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000276:immunology / Q000378:metabolism; D005260:Female; D006801:Humans; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications / Q000175:diagnosis* / Q000276:immunology / Q000378:metabolism; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology / Q000378:metabolism