title: Isolated peripheral nerve relapse masquerading as Guillain-Barré syndrome in a patient with acute lymphoblastic leukemia.
abstract: We report a 30 year old patient with acute lymphoblastic leukemia (ALL) whose leukemic relapse presented as an isolated symmetrical peripheral neuropathy with facial diplegia. Initially, this was consistent with a Guillain-Barré syndrome but the peripheral nerve biopsy revealed leukaemic infiltration. This was followed by a systemic relapse. Reports of peripheral nerve infiltration are scarce and to the best of our knowledge this is the first documented case of peripheral polyneuropathy as a presenting manifestation of ALL relapse.
authors.affiliation: Unité de Greffe de Moëlle, Hopital Haut-Lévêque, Pessac, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Boiron
authors.forename: E
authors.initials: E
authors.lastname: Ellie
authors.forename: A
authors.initials: A
authors.lastname: Vital
authors.forename: A
authors.initials: A
authors.lastname: Lagueny
authors.forename: C
authors.initials: C
authors.lastname: Vital
authors.forename: J
authors.initials: J
authors.lastname: Julien
authors.forename: J
authors.initials: J
authors.lastname: Reiffers
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D017254:Leukemic Infiltration / Q000175:diagnosis*; D010525:Peripheral Nerves / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis*; D011129:Polyradiculoneuropathy / Q000175:diagnosis*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D012008:Recurrence