title: Multicystic dysplastic kidney in children: US follow-up.
abstract: Eighty-one cases of multicystic dysplastic kidney (MCDK) in children were diagnosed over the past 11 years at the authors' institution: 25 children had their kidneys surgically removed, eight with bilateral total involvement died, and 48 underwent serial follow-up ultrasonography (US) of their kidneys. Follow-up included 193 serial ultrasound (US) studies (mean, four per patient) for a total of 1,468 months (mean, 30.5 months). In the 48 patients followed up, 32 (67%) kidneys showed a decrease in size, nine (19%) showed no change, and five (10%) increased in size, and in two (4%), a change in size could not be determined. In seven of the 48 (15%) children, the MCDKs decreased in size, and, at follow-up US, no renal tissue could be found. In those patients in whom MCDKs decreased in size. Serial US characteristics changed from predominantly an enlarged cystic structure to a small dysplastic or absent kidney. Two of the five kidneys that increased in size were surgically removed, and MCDK was pathologically confirmed. A nonsurgical approach to the treatment of patients with MCDK is supported by this study.
authors.affiliation: Department of Radiology, Children's Hospital Medical Center, Cincinnati, OH 45229-2899.
authors.forename: J L
authors.initials: JL
authors.lastname: Strife
authors.forename: A S
authors.initials: AS
authors.lastname: Souza
authors.forename: D R
authors.initials: DR
authors.lastname: Kirks
authors.forename: C F
authors.initials: CF
authors.lastname: Strife
authors.forename: M J
authors.initials: MJ
authors.lastname: Gelfand
authors.forename: J
authors.initials: J
authors.lastname: Wacksman
mesh_terms: D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities* / Q000000981:diagnostic imaging; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000628:therapy; D008297:Male; D011247:Pregnancy; D013997:Time Factors; D016216:Ultrasonography, Prenatal