Liver disease from surreptitious administration of urethane.
We report subacute necrosis, peliosis hepatis, venoocclusive disease and hepatic angiosarcoma after long-term administration of urethane. We take this to be the 12th case of urethane-induced hepatitis and the first associated with vascular liver tumor.
Cadranel
J F
JF
Service d'hepato-gastro-enterologie, Hôpital Saint-Antoine, Paris, France.
Legendre
C
C
Desaint
B
B
Delamarre
N
N
Florent
C
C
Levy
V G
VG
D002908:Chronic Disease; D005260:Female; D006394:Hemangiosarcoma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D009336:Necrosis; D010382:Peliosis Hepatis / Q000139:chemically induced* / Q000473:pathology; D012651:Self Medication / Q000009:adverse effects*; D014520:Urethane / Q000009:adverse effects*
D014520:Urethane