[Apoptosis in radiosensitive malignant tumors].
This study reported the radiation induced apoptosis in 6 cases with malignancies that were observed rapid tumor regression with radiotherapy up to 10 Gy. Microscopic examinations of 6 cases revealed the tumor cell number reduction and the appearance of apoptotic cells in the irradiated cases. It is suggested that the radiation-induced apoptosis plays an important role in rapid tumor regression by radiotherapy and occurs not only in lymphoma which has been recently reported in vitro but also in carcinoma.
Akagi
Y
Y
Department of Radiology, Hiroshima University School of Medicine.
Hirokawa
Y
Y
Fujita
M
M
Kiriu
H
H
Kashimoto
K
K
Kashiwado
K
K
Ito
K
K
D017209:Apoptosis / Q000502:physiology / Q000528:radiation effects*; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D005887:Gingival Neoplasms / Q000532:radiotherapy*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000532:radiotherapy*; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D011836:Radiation Tolerance