Blunted growth hormone responses to growth hormone-releasing factor and to clonidine in panic disorder.
Blunted growth hormone (GH) responses to growth hormone-releasing factor (GH-RF) and clonidine have been reported in patients with panic disorder. In this study GH-RF and clonidine were administered to 13 patients with panic disorder and 20 healthy volunteers. Compared to the normal subjects, the patients with panic disorder had significantly blunted GH responses after both GH-RF and clonidine.
Tancer
M E
ME
Section on Anxiety and Affective Disorders, NIMH. Bethesda, MD 20892.
Stein
M B
MB
Black
B
B
Uhde
T W
TW
D000328:Adult; D000704:Analysis of Variance; D003000:Clonidine / Q000494:pharmacology; D003937:Diagnosis, Differential; D004311:Double-Blind Method; D005260:Female; D013006:Growth Hormone / Q000097:blood*; D013007:Growth Hormone-Releasing Hormone / Q000494:pharmacology; D006801:Humans; D008297:Male; D016584:Panic Disorder / Q000097:blood / Q000175:diagnosis*
D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone; D003000:Clonidine