title: Percutaneous ultrasound-guided biopsy. Fine needle biopsy, cutting needle biopsy, or both?
abstract: The results of 155 US-guided cutting needle biopsies, mainly of abdominal and transthoracic lesions, were reviewed to assess the diagnostic accuracy of the method. A fine needle biopsy (FNB) was additionally performed in 99 of the patients. Sufficient material for histologic and cytologic analysis was obtained in 88% (137/155) and 98% (97/99), and a correct benign or malignant diagnosis was made in 87% and 88%, respectively. Among the 99 combined biopsies the corresponding figures were 100% and 97%, respectively. The proportions of inconclusive and false-negative results among histologic samples were 0% and 4% (2/57), in FNBs 7% (7/99) and 5% (3/56), and in combined examinations 3% (3/99) and 0%. One major complication, Streptococcus faecalis sepsis, occurred. The combined use of FNB and histologic biopsy increases the proportion of correct diagnoses about 10% without increasing the complications.
authors.affiliation: Department of Diagnostic Radiology, Oulu University Central Hospital, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Tikkakoski
authors.forename: M
authors.initials: M
authors.lastname: Päivänsalo
authors.forename: T
authors.initials: T
authors.lastname: Siniluoto
authors.forename: S
authors.initials: S
authors.lastname: Hiltunen
authors.forename: T
authors.initials: T
authors.lastname: Typpö
authors.forename: P
authors.initials: P
authors.lastname: Jartti
authors.forename: M
authors.initials: M
authors.lastname: Apaja-Sarkkinen
mesh_terms: D000008:Abdominal Neoplasms / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000379:methods; D001707:Biopsy, Needle / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D013899:Thoracic Neoplasms / Q000473:pathology; D014463:Ultrasonography