Observation of a conformational effect in peptide molecule by reversed-phase high-performance liquid chromatography.
RP-HPLC of analogues of oxytocin containing a reduced peptide bond was studied using various columns and buffers. Anomalous behavior of one analogue served as a basis for the discussion of possible conformational consequences of this substitution.
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Selectide Corporation, Tucson, AZ 85737.
D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D008969:Molecular Sequence Data; D010121:Oxytocin / Q000031:analogs & derivatives; D010455:Peptides / Q000737:chemistry* / Q000302:isolation & purification; D011487:Protein Conformation
D010455:Peptides; D010121:Oxytocin