title: Prostaglandin prophylaxis and bladder function after vaginal hysterectomy: a prospective randomised study.
abstract: OBJECTIVE
  To assess the efficacy of prostaglandins in enhancing bladder function after vaginal hysterectomy.
  
  
  METHODS
  Prospective randomised study of women who underwent vaginal hysterectomy between November 1989 and August 1990.
  
  
  METHODS
  Sackler School of Medicine Tel Aviv University Medical Center, Department of Obstetrics and Gynaecology 'B'.
  
  
  METHODS
  24 women who underwent vaginal hysterectomy and anterior and posterior colporrhaphy for prolapse.
  
  
  METHODS
  Administration of prostaglandin F2 alpha 5 mg intravesically or E2 3 mg intravaginally versus 100 ml saline intravesically (control) daily, starting on the first postoperative day, until adequate spontaneous voiding was established.
  
  
  RESULTS
  Women receiving PGE2 resumed spontaneous bladder functions earlier, required significantly fewer days catheterisation and had significantly less febrile morbidity compared to women in the control group or PGE2 group.
  
  
  CONCLUSIONS
  Prostaglandins PGE2 intravaginally are beneficial in enhancing functions after vaginal hysterectomy [corrected].
authors.affiliation: University of Southern California School of Medicine, Women's Hospital, Los Angeles 90033.
authors.forename: A
authors.initials: A
authors.lastname: Bergman
authors.forename: Y
authors.initials: Y
authors.lastname: Mushket
authors.forename: D
authors.initials: D
authors.lastname: Gordon
authors.forename: M P
authors.initials: MP
authors.lastname: David
mesh_terms: D000328:Adult; D000368:Aged; D015237:Dinoprost / Q000627:therapeutic use*; D015232:Dinoprostone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects*; D008875:Middle Aged; D010570:Pessaries; D011446:Prospective Studies; D001743:Urinary Bladder / Q000503:physiopathology*; D014555:Urination Disorders / Q000503:physiopathology / Q000517:prevention & control*
chemical_list: D015237:Dinoprost; D015232:Dinoprostone