[Somatostatin receptor scintigraphy. A new imaging procedure for the specific demonstration of carcinoids of the small intestine].
Scintigraphy with a radiolabelled somatostatin analog represents a new highly specific approach in the diagnostic work-up of receptor-positive APUD tumours and their metastases. We present our preliminary results with somatostatin receptor scintigraphy in 15 patients with histologically proven midgut carcinoid. 5 out of 6 primary tumour sites (83%) and 90% of the known metastatic lesions could be detected; unknown metastatic lesions were seen in 5 patients. Compared with other nuclear medicine procedures somatostatin receptor scintigraphy is able to detect all tumour sites within hours. This advantage will promote the acceptance of this sensitive and specific imaging modality by the clinicians with regard to preoperative work-up and symptomatic therapy with a somatostatin analog.
Dörr
U
U
Klinik für Nuklearmedizin, Katharinenhospital, Stuttgart.
Räth
U
U
Schürmann
G
G
Höring
E
E
Bach
D
D
Wurm
K
K
Scholz
M
M
Adrian
H J
HJ
Bihl
H
H
D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D007414:Intestinal Neoplasms / Q000000981:diagnostic imaging*; D007421:Intestine, Small / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D008722:Methods; D008875:Middle Aged; D015282:Octreotide / Q000031:analogs & derivatives; D004369:Pentetic Acid / Q000031:analogs & derivatives; D011877:Radionuclide Imaging; D011986:Receptors, Somatotropin; D013997:Time Factors
D007205:Indium Radioisotopes; D011986:Receptors, Somatotropin; C071632:SDZ 215-811; D004369:Pentetic Acid; D015282:Octreotide