title: A biosocial model of the alcohol-aggression relationship.
abstract: Four of alcohol's dose- and rate-dependent pharmacological properties may increase the likelihood of human aggression. As an anxiolytic, alcohol is capable of reducing the inhibitory effect of fear on manifestation of aggressive behavior. As a psychomotor stimulant, alcohol can potentiate aggressive behavior, once evoked, or lower the threshold for such evocation. Alcohol-related disruption of certain higher order cognitive functions may reduce the inhibitory control generally exercised by previously established knowledge and decrease ability to plan in the face of threat or punishment. Finally, alcohol's ability to increase pain sensitivity may increase the likelihood of defensive aggression. Discussion of the nature and relevance of these pharmacological properties is structured according to a heuristic and synthetic schema, predicated upon consideration of an inhibitory neuropsychological structure--the individually and culturally determined general expectancy set.
authors.affiliation: Department of Psychology, McGill University, Montreal, Quebec, Canada.
authors.forename: R O
authors.initials: RO
authors.lastname: Pihl
authors.forename: J B
authors.initials: JB
authors.lastname: Peterson
authors.forename: M A
authors.initials: MA
authors.lastname: Lau
mesh_terms: D000374:Aggression / Q000187:drug effects*; D000428:Alcohol Drinking; D000435:Alcoholic Intoxication; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D000431:Ethanol / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010146:Pain; D010919:Placebos; D011596:Psychomotor Disorders / Q000209:etiology; D018079:Receptors, GABA / Q000187:drug effects; D012701:Serotonin / Q000378:metabolism
chemical_list: D010919:Placebos; D018079:Receptors, GABA; D012701:Serotonin; D000431:Ethanol