Wegener's granulomatosis presenting as a primary seizure disorder with brain lesions demonstrated by magnetic resonance imaging.
Since the earliest attempt by Klinger in 1931 to describe the systemic vasculitis subsequently characterized in 1936 by Wegener as Wegener's granulomatosis, this disorder has been reported to present in a number of differing fashions. No previous description relates Wegener's presenting as a seizure disorder, and no reports of MRI of the brain in such patients exists. We relate such a case, along with MRI findings, prior to and after treatment, with a review of neurologic manifestations of the disorder.
Miller
K S
KS
Trident Regional Medical Center, Charleston, SC.
Miller
J M
JM
D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis*; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000175:diagnosis*