title: Multistep deprotection for peptide chemistry.
abstract: This review article focuses on some concepts which make use of special classes of protecting groups (protected protecting groups) in peptide synthesis. Terms such as gradative deprotection, dual deprotection, two-step deprotection, safety-catch protection and multidetachable protecting systems are discussed, and the general mechanistic considerations for the deprotection process are described.
authors.affiliation: Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague.
authors.forename: M
authors.initials: M
authors.lastname: Patek
mesh_terms: D002625:Chemistry, Organic / Q000379:methods / Q000639:trends; D008956:Models, Chemical; D010455:Peptides / Q000138:chemical synthesis*
chemical_list: D010455:Peptides