The roles of heat shock proteins and immediate early genes in central nervous system normal function and pathology.
The expression and transcription of heat shock proteins and immediate early genes in the central nervous system are greatly affected by disease and injury. However, the participation of these genes in both normal and pathophysiologic function is uncertain. Experiments performed this past year shed light on the possible roles of heat shock proteins and immediate early genes in neurologic tissue.
Chopp
M
M
Department of Neurology, Henry Ford Hospital, Detroit, MI 48202.
D000544:Alzheimer Disease / Q000378:metabolism / Q000503:physiopathology*; D001921:Brain / Q000378:metabolism / Q000503:physiopathology; D002545:Brain Ischemia / Q000276:immunology* / Q000503:physiopathology; D002490:Central Nervous System / Q000502:physiology* / Q000503:physiopathology; D005260:Female; D005334:Fever / Q000378:metabolism / Q000503:physiopathology; D015870:Gene Expression / Q000235:genetics / Q000502:physiology; D006360:Heat-Shock Proteins / Q000276:immunology* / Q000502:physiology*; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D010766:Phosphorylation; D012333:RNA, Messenger / Q000276:immunology / Q000502:physiology; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000276:immunology
D006360:Heat-Shock Proteins; D012333:RNA, Messenger; D016159:Tumor Suppressor Protein p53