title: Screening of esophageal and gastric cancer by occult blood bead detector.
abstract: A previously described bead method used to detect blood is simple, cheap, and effective; it can be repeated periodically. In 11 provinces in China, 233,825 persons (age range, 30-70 years) were screened. A positive occult blood test result was found in 28,557 persons (12%). Of these, 16,918 underwent a gastroscopy, resulting in the detection of 581 cancers that were located in similar frequencies in the esophagus, gastric cardia, and gastric body; 70% of the lesions were in an early or moderately advanced stage. Among 119 patients with early-stage cancer, the 3-year survival rate was 98.3%. After preliminary screening of cancer, the 4-year follow-up found a mortality rate in the group with negative occult blood test results that was only 25% of that of the positive group. Preliminary yearly screening would detect more early cancers and fewer advanced cancers. The mortality rate of esophageal and gastric cancer might be reduced drastically.
authors.affiliation: Department of Cancer Prevention and Detection, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing.
authors.forename: D X
authors.initials: DX
authors.lastname: Qin
authors.forename: G Q
authors.initials: GQ
authors.lastname: Wang
authors.forename: J H
authors.initials: JH
authors.lastname: Zuo
authors.forename: X H
authors.initials: XH
authors.lastname: Zhang
authors.forename: F L
authors.initials: FL
authors.lastname: Yuan
authors.forename: M S
authors.initials: MS
authors.lastname: Li
authors.forename: C R
authors.initials: CR
authors.lastname: Wu
authors.forename: C L
authors.initials: CL
authors.lastname: Ju
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D004938:Esophageal Neoplasms / Q000401:mortality / Q000517:prevention & control*; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000295:instrumentation*; D008875:Middle Aged; D009780:Occult Blood; D013274:Stomach Neoplasms / Q000401:mortality / Q000517:prevention & control*; D015996:Survival Rate