title: A temporary antibiotic-loaded joint replacement system for management of complex infections involving the hip.
abstract: Management of the infected hip replacement associated with substantial loss of bone, especially segmental loss of the proximal femur, is a challenging problem. In this report, the authors outline the development of an immediate-fit, custom-made, antibiotic-selective replacement system for the hip and proximal femur, to help maintain limb length, joint stability, and mobility of the patient. Despite the initial relatively crude design, it was a valuable adjunct in the management of 15 consecutive cases. A more sophisticated and versatile system has since been developed for use in straightforward and complex cases.
authors.affiliation: Department of Orthopaedics, University of British Columbia, Vancouver, Canada.
authors.forename: C P
authors.initials: CP
authors.lastname: Duncan
authors.forename: C
authors.initials: C
authors.lastname: Beauchamp
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control*; D001862:Bone Resorption / Q000150:complications / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006622:Hip Prosthesis / Q000295:instrumentation / Q000379:methods* / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000517:prevention & control*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents