Pasteurella multocida pneumonia in a man with AIDS and nontraumatic feline exposure.
A case of acute pneumonia due to Pasteurella multocida ssp multocida occurred in a young man with AIDS and chronic sinusitis. The pneumonia was diagnosed by bronchoscopy and responded to treatment with aztreonam. Epidemiologic investigation revealed the case was temporally related to nontraumatic exposure to cat secretions that the patient presumably had acquired via an aerosol. The cat's oral cavity was cultured and an isolate of P multocida ssp multocida with identical biochemical reactions, DNA restriction patterns, and nearly identical fatty acid profile to that of the patient's isolate was obtained suggesting they were identical strains and therefore epidemiologically linked. A control strain with identical biochemical reactions and antibiotic sensitivities exhibited different patterns. To our knowledge, this is the first such reported infection in a patient infected with human immunodeficiency virus.
Drabick
J J
JJ
Department of Bacterial Diseases, Walter Reed Army Institute of Research, Washington, DC 20307-5100.
Gasser
R A
RA
Saunders
N B
NB
Hadfield
T L
TL
Rogers
L C
LC
Berg
B W
BW
Drabick
C J
CJ
D017088:AIDS-Related Opportunistic Infections; D000328:Adult; D000818:Animals; D002415:Cats / Q000382:microbiology*; D002908:Chronic Disease; D004269:DNA, Bacterial / Q000032:analysis; D004781:Environmental Exposure; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D008297:Male; D010326:Pasteurella Infections; D016979:Pasteurella multocida / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification; D011014:Pneumonia / Q000382:microbiology*; D012852:Sinusitis / Q000150:complications; D015047:Zoonoses
D004269:DNA, Bacterial; D005227:Fatty Acids