title: The dynamics of multiple sclerosis. The Charcot Lecture.
abstract: The history of our understanding of the pathogenesis and pathophysiology of multiple sclerosis are reviewed in the context of Charcot's contribution. The implications for treatment of the new knowledge gained from studies during life of pathology and pathogenesis (by MRI) and pathophysiology (by evoked potentials) are reviewed.
authors.affiliation: NMR Research Group, Institute of Neurology, Queen Square, London, UK.
authors.forename: W I
authors.initials: WI
authors.lastname: McDonald
mesh_terms: D049672:History, 19th Century; D006801:Humans; D009103:Multiple Sclerosis / Q000266:history* / Q000503:physiopathology