title: MR microscopy of the rat lung using projection reconstruction.
abstract: Projection reconstruction has been implemented with self-refocused selection pulses on a small bore, 2.0 T MR microscope, to allow imaging of lung parenchyma. Scan synchronous ventilation and cardiac gating have been integrated with the sequence to minimize motion artifacts. A systematic survey of the pulse sequence parameters has been undertaken in conjunction with the biological gating parameters to optimize resolution and signal-to-noise (SNR). The resulting projection images with effective echo time of < 300 microseconds allow definition of lung parenchyma with an SNR improvement of approximately 15 x over a more conventional 2DFT short echo gradient sequence.
authors.affiliation: Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
authors.forename: S L
authors.initials: SL
authors.lastname: Gewalt
authors.forename: G H
authors.initials: GH
authors.lastname: Glover
authors.forename: L W
authors.initials: LW
authors.lastname: Hedlund
authors.forename: G P
authors.initials: GP
authors.lastname: Cofer
authors.forename: J R
authors.initials: JR
authors.lastname: MacFall
authors.forename: G A
authors.initials: GA
authors.lastname: Johnson
mesh_terms: D000818:Animals; D005260:Female; D008168:Lung / Q000166:cytology*; D008279:Magnetic Resonance Imaging; D008853:Microscopy; D051381:Rats; D017207:Rats, Sprague-Dawley