Multiple primary intracranial tumors and association of intra- and extracranial tumors. An autopsy study.
In 37504 autopsies performed during the last 3 decades at the Department of Pathology of Albert Szent-Györgyi Medical University (Szeged, Hungary) gliomas were found in 498 cases. These gliomas were associated with other types of intra- or extracranial tumors in 1.2-3.2% of the cases. Despite the male predominance observed in other types of multiple tumors, the multiple intracranial tumors and the intracranial tumors associated with extracranial malignancies were more frequent in females (possible role of hormonal influences). A relatively frequent association of various intracranial tumors with gastrointestinal carcinomas and in one quarter of the cases with extracranial benign tumors indicates that genetic factors may be involved in the pathomechanism.
Tiszlavicz
L
L
Department of Pathology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
D000328:Adult; D000368:Aged; D001344:Autopsy; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D005910:Glioma / Q000473:pathology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology / Q000473:pathology*; D012189:Retrospective Studies