title: Three small nucleolar RNAs of unique nucleotide sequences.
abstract: Three small RNA species were detected in human cells, and their cDNAs were synthesized and cloned. These RNAs are nucleolar, are 207, 154, and 135 nucleotides long, and are named E1, E2, and E3, respectively, and their unique nucleotide sequences suggest that they may belong to an additional family of small nucleolar RNAs. The 5' ends of these three RNAs do not appear to have a trimethylguanosine cap or another type of cap. Apparent homologs of these three RNAs were detected in mouse, rabbit, and frog cells, suggesting their universal importance. They are housekeeping RNA species, since they are present in all rabbit tissues analyzed.
authors.affiliation: Department of Pathology, St. Louis University School of Medicine, MO 63104-1028.
authors.forename: E A
authors.initials: EA
authors.lastname: Ruff
authors.forename: O J
authors.initials: OJ
authors.lastname: Rimoldi
authors.forename: B
authors.initials: B
authors.lastname: Raghu
authors.forename: G L
authors.initials: GL
authors.lastname: Eliceiri
mesh_terms: D001483:Base Sequence; D002466:Cell Nucleolus / Q000737:chemistry*; D015342:DNA Probes; D006801:Humans; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012342:RNA, Small Nuclear / Q000235:genetics / Q000302:isolation & purification*; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
chemical_list: D015342:DNA Probes; D012342:RNA, Small Nuclear