title: Persistent hyperbilirubinemia in a healthy thoroughbred horse.
abstract: Persistent hyperbilirubinemia and icterus are described in a healthy 4-year-old Thoroughbred horse. Hyperbilirubinemia was not related to food intake and was not associated with evidence of increased hemolysis or with acquired hepatic disease. The hyperbilirubinemia was thought to be a result of inappropriate conjugation of bilirubin rather than any abnormality in bilirubin uptake or excretion. The bilirubinemia in this horse appears most similar to a human syndrome, caused by a familial deficiency of bilirubin-uridine diphosphate glucuronyl transferase.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
authors.forename: T J
authors.initials: TJ
authors.lastname: Divers
authors.forename: K A
authors.initials: KA
authors.lastname: Schappel
authors.forename: R W
authors.initials: RW
authors.lastname: Sweeney
authors.forename: B C
authors.initials: BC
authors.lastname: Tennant
mesh_terms: D000818:Animals; D003414:Crigler-Najjar Syndrome / Q000662:veterinary; D006734:Horse Diseases / Q000175:diagnosis*; D006736:Horses; D006932:Hyperbilirubinemia / Q000175:diagnosis / Q000662:veterinary*; D007565:Jaundice / Q000175:diagnosis / Q000662:veterinary; D008297:Male