title: Helium-oxygen mixture in respiratory distress syndrome: a double-blind study.
abstract: In a randomized, controlled trial, the lungs of infants with respiratory distress syndrome were ventilated with either a helium-oxygen mixture or a nitrogen-oxygen mixture. In the helium-oxygen group, infants required a lower inspired oxygen concentration and a shorter duration of ventilation. There were also fewer deaths and fewer cases of bronchopulmonary dysplasia in the helium-oxygen group.
authors.affiliation: Service de réanimation néonatale, Hôpital Pellegrin, France.
authors.forename: C
authors.initials: C
authors.lastname: Elleau
authors.forename: R I
authors.initials: RI
authors.lastname: Galperine
authors.forename: H
authors.initials: H
authors.lastname: Guenard
authors.forename: J L
authors.initials: JL
authors.lastname: Demarquez
mesh_terms: D000403:Airway Resistance; D001794:Blood Pressure; D001997:Bronchopulmonary Dysplasia / Q000209:etiology; D004311:Double-Blind Method; D006371:Helium / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007442:Intubation, Intratracheal; D009584:Nitrogen / Q000627:therapeutic use*; D010100:Oxygen / Q000097:blood / Q000627:therapeutic use*; D001261:Pulmonary Atelectasis / Q000209:etiology; D012119:Respiration / Q000502:physiology; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D006371:Helium; C038949:heliox; D009584:Nitrogen; D010100:Oxygen