[Polycyclic aromatic alkaloids. 9. Synthesis and antifungal activity of diazafluoroanthene alkaloids].
The total syntheses of the alkaloids eupolauridine-N-oxide (2) and eupolauridine-di-N-oxide (3) are described. The compounds 2 and 3 possess lower anticandidal activity than eupolauridine (1).
Bracher
F
F
Institut für Pharmazeutische Chemie, Technischen Universität Braunschweig.
D000470:Alkaloids / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002175:Candida / Q000187:drug effects; D005449:Fluorenes / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests
D000470:Alkaloids; D000935:Antifungal Agents; D005449:Fluorenes