Methionine metabolism: a window on carcinogenesis?
Recent experimental evidence links changes in methionine metabolism to the onset and progression of cancer. Aberrant methylation reactions and polyamine synthesis may alter genome stability, gene expression, and cell proliferation.
Gatton-Umphress
T L
TL
University of Health Sciences, Kansas City, Mo.
Weber
K A
KA
Seidler
N W
NW
D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D004249:DNA Damage; D004260:DNA Repair; D006801:Humans; D008715:Methionine / Q000378:metabolism*; D009369:Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism; D015513:Oncogene Proteins / Q000378:metabolism
D015513:Oncogene Proteins; D008715:Methionine