title: Cutaneous necrosis resulting from protein S deficiency and increased antiphospholipid antibody in a patient with systemic lupus erythematosus.
abstract: A 23-year-old woman with widespread cutaneous necrosis resulting from protein S deficiency and increased antiphospholipid antibody in the setting of systemic lupus erythematosus is described. Our report illustrates the complex nature of evaluation of skin lesions in patients with active systemic lupus erythematosus.
authors.affiliation: Department of Dermatology, State University of New York at Buffalo.
authors.forename: M S
authors.initials: MS
authors.lastname: Amster
authors.forename: J
authors.initials: J
authors.lastname: Conway
authors.forename: M
authors.initials: M
authors.lastname: Zeid
authors.forename: S
authors.initials: S
authors.lastname: Pincus
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D009336:Necrosis; D018455:Protein S Deficiency; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology
chemical_list: D017152:Antibodies, Antiphospholipid