Target apex-seeking in factor analysis of medical image sequences.
The aim of factor analysis of medical image sequences (FAMIS) is to estimate a limited number of physical or physiological fundamental functions. Its oblique rotation stage strongly affects the quality and the interpretation of the resulting estimates (factors and factor images). A new target apex-seeking method which integrates physical or physiological knowledge in this stage is described. This knowledge concerns some of the fundamental functions and reacts on the determination of all the factors. A simulated spectral study illustrates the method. We discuss its properties in comparison with the other approaches using a priori physical or physiological information.
Buvat
I
I
U66 INSERM, Institut Gustave Roussy, Villejuif, France.
Benali
H
H
Frouin
F
F
Bazin
J P
JP
Di Paola
R
R
D003198:Computer Simulation; D005163:Factor Analysis, Statistical; D006801:Humans; D008961:Models, Structural; D011877:Radionuclide Imaging / Q000706:statistics & numerical data*