Preliminary Tl-201 SPECT for assessment of treatment efficacy in three patients with pancreatic cancer.
To evaluate treatment efficacy, Tl-201 SPECT was performed in three patients with pancreatic cancer. In all of the patients, the degree of Tl-201 uptake by tumor, evaluated from the tumor-liver uptake ratio of Tl-201 activity, correlated well with alterations in serum level of a tumor marker (CA 19-9, DUPAN-2) after treatment. One of the patients showed no tumor shrinkage on CT after treatment; however, Tl-201 SPECT demonstrated reduced uptake in the tumor coupled with a decreased level of CA 19-9. These results suggest that Tl-201 SPECT may become a new tool for assessing the efficacy of treatment in pancreatic cancer.
Suga
K
K
Department of Radiology, Yamaguchi University School of Medicine, Ube, Japan.
Fujita
T
T
Nakada
T
T
Yoneshiro
S
S
Uchisako
H
H
Nishigauchi
K
K
Nakanishi
T
T
Hamada
Y
Y
D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000628:therapy*; D013514:Surgical Procedures, Operative; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
D013794:Thallium Radioisotopes