title: Structure of an antimutagen from Carmona retusa leaves.
abstract: An antimutagenic compound was isolated from the leaves of Carmona retusa (Vahl) Masam. Its structure has been elucidated by spectral analysis to be 4-hydroxy-7,8,11,12,15,7',8',11',12',15'-decahydro-beta, psi-carotene. The results of the Micronucleus Test, an in vivo method, showed that the isolated antimutagenic compound reduced by approximately 68.4% the number of micronucleated polychromatic erythrocytes induced by tetracycline, a known mutagen.
authors.affiliation: Institute of Chemistry, University of the Philippines, Quezon City.
authors.forename: I M
authors.initials: IM
authors.lastname: Villaseñor
authors.forename: D A
authors.initials: DA
authors.lastname: Edu
authors.forename: J B
authors.initials: JB
authors.lastname: Bremner
mesh_terms: D000818:Animals; D016587:Antimutagenic Agents / Q000737:chemistry* / Q000302:isolation & purification; D002338:Carotenoids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015162:Micronucleus Tests; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D016587:Antimutagenic Agents; C079485:4-hydroxy-7,7',8,8',11,11',12,12',15,15'-decahydro-beta,psi-carotene; D002338:Carotenoids