Immunopathogenesis of pulmonary tuberculosis.
Antimicrobial therapy quickly eradicates susceptible bacilli, but the fight against drug-resistant disease must be waged entirely by host defenses. Knowledge of the two main types of immune response against tuberculosis and of how to manipulate those mechanisms--leading to precisely designed recombinant BCG vaccines--is essential to mounting an effective attack on the current epidemic.
Dannenberg
A M
AM
Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore.
D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use; D004195:Disease Models, Animal; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D011817:Rabbits; D012720:Severity of Illness Index; D013601:T-Lymphocytes / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology
D000995:Antitubercular Agents