title: Meizothrombin: active intermediate formed during prothrombinase-catalyzed activation of prothrombin.
authors.affiliation: Haematologic Technologies, Inc., Essex Junction, Vermont 05452.
authors.forename: M F
authors.initials: MF
authors.lastname: Doyle
authors.forename: P E
authors.initials: PE
authors.lastname: Haley
mesh_terms: D000818:Animals; D001665:Binding Sites; D001780:Blood Coagulation Tests / Q000379:methods; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D004792:Enzyme Precursors / Q000032:analysis / Q000378:metabolism* / Q000494:pharmacology*; D004950:Esterases / Q000378:metabolism; D005165:Factor V / Q000378:metabolism*; D015943:Factor Va / Q000378:metabolism; D005263:Femoral Artery / Q000187:drug effects / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents; D007700:Kinetics; D008297:Male; D008954:Models, Biological; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D015539:Platelet Activation / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects; D011486:Protein C / Q000378:metabolism*; D011516:Prothrombin / Q000378:metabolism*; D011817:Rabbits; D013053:Spectrophotometry / Q000379:methods; D013379:Substrate Specificity; D013917:Thrombin / Q000032:analysis / Q000378:metabolism* / Q000494:pharmacology*; D013925:Thromboplastin / Q000378:metabolism*
chemical_list: D004792:Enzyme Precursors; D007202:Indicators and Reagents; D011486:Protein C; D015943:Factor Va; D005165:Factor V; D011516:Prothrombin; D013925:Thromboplastin; D004950:Esterases; D013917:Thrombin; C026812:meizothrombin