title: Effects of a preload increase on ventricular filling in coronary artery disease.
abstract: This study was conducted to investigate the effects of a preload increase on ventricular filling dynamics in 50 coronary artery disease patients both before and immediately after leg elevation. Mitral and tricuspid peak E and A velocities and the mitral E/A velocity ratio increased after leg elevation whereas isovolumic relaxation time and mitral deceleration time decreased. The increase in tricuspid peak A velocity after leg elevation was related to the positivity of the exercise stress test (p = 0.01). The increase in mitral peak A velocity was related to the history of old myocardial infarction (p = 0.006).
authors.affiliation: Athens General Hospital, Athens University Medical School, Greece.
authors.forename: Z S
authors.initials: ZS
authors.lastname: Kyriakides
authors.forename: D T
authors.initials: DT
authors.lastname: Kremastinos
authors.forename: I A
authors.initials: IA
authors.lastname: Paraskevaides
authors.forename: A
authors.initials: A
authors.lastname: Koukoulas
authors.forename: F
authors.initials: F
authors.lastname: Panou
authors.forename: P
authors.initials: P
authors.lastname: Toutouzas
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology*; D001810:Blood Volume / Q000502:physiology*; D002306:Cardiac Volume / Q000502:physiology; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003971:Diastole / Q000502:physiology*; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology; D014261:Tricuspid Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology