[Acute cerebellar syndrome in preventive lithium treatment and atypical pneumonia in Q fever].
CNS-involvement in Coxiella burnetii infection is rare. Severe cerebellar symptoms with incomplete restitution were observed in 3 patients who developed Q-fever pneumonia associated with a long-term prophylaxis with lithium for manic-depressive disorder. Several pathophysiological mechanisms for these complications are discussed and a specific toxic-infectious interaction is suggested.
Pfadenhauer
K
K
Neurologische Klinik mit klinischer Neurophysiologie, Zentralklinikum Augsburg.
Stapf
U
U
D000208:Acute Disease; D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy*; D002524:Cerebellar Ataxia / Q000139:chemically induced / Q000175:diagnosis; D002526:Cerebellar Diseases / Q000139:chemically induced* / Q000175:diagnosis; D003527:Cyclothymic Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications*; D011778:Q Fever / Q000150:complications*; D013577:Syndrome
D008094:Lithium