Salvage and interconversion of purines in developing Artemia.
Incorporation of the radiolabelled purine bases adenine, guanine and hypoxanthine into acid soluble fraction, RNA and DNA nucleotides during the early larval development of Artemia sp. was studied. Adenine was the best precursor and guanine the poorest. The adenine phosphoribosyltransferase (APRT) activity was considerably higher than that of hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and these activities did not significantly change throughout larval development. The pattern of purine interconversion was dependent on naupliar age. Conversion of [14C]adenine and [14C]hypoxanthine into guanine nucleotides increased with time of development. However, the conversion of [14C]guanine into [14C]adenine nucleotides was very low.
Rotllan
P
P
Instituto de Investigaciones Biomédicas del C.S.I.C., Madrid, Spain.
Liras
A
A
Llorente
P
P
D000225:Adenine / Q000378:metabolism; D000227:Adenine Nucleotides / Q000378:metabolism; D000228:Adenine Phosphoribosyltransferase / Q000378:metabolism; D000818:Animals; D001156:Artemia / Q000378:metabolism*; D002250:Carbon Radioisotopes; D006150:Guanine Nucleotides / Q000378:metabolism; D019271:Hypoxanthine; D007041:Hypoxanthine Phosphoribosyltransferase / Q000378:metabolism; D007042:Hypoxanthines / Q000378:metabolism; D007814:Larva / Q000378:metabolism; D011687:Purines / Q000378:metabolism*
D000227:Adenine Nucleotides; D002250:Carbon Radioisotopes; D006150:Guanine Nucleotides; D007042:Hypoxanthines; D011687:Purines; D019271:Hypoxanthine; D000228:Adenine Phosphoribosyltransferase; D007041:Hypoxanthine Phosphoribosyltransferase; D000225:Adenine