Kaposi's sarcoma with visceral involvement after intraarticular and epidural injections of corticosteroids.
Kaposi's sarcoma has been reported in patients receiving immunosuppressive therapy, most of whom are organ transplant recipients. The development of Kaposi's sarcoma after treatment with corticosteroids has been reported in only 38 patients who have not had acquired immunodeficiency syndrome or undergone organ transplantation. Cutaneous Kaposi's sarcoma developed 2 months after intraarticular steroid injections in a man with ulnar nerve entrapment. The lesions regressed spontaneously after 3 months but reappeared with visceral involvement 18 months later, shortly after initiation of a course of epidural steroid injections for treatment of low back pain. The cutaneous lesions and some visceral lesions rapidly regressed after cessation of treatment.
Trattner
A
A
Department of Dermatology, Beilinson Medical Center, Petah Tiqva, Israel.
Hodak
E
E
David
M
M
Neeman
A
A
Sandbank
M
M
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D001623:Betamethasone / Q000009:adverse effects / Q000031:analogs & derivatives*; D005938:Glucocorticoids; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects / Q000031:analogs & derivatives*; D000077555:Methylprednisolone Acetate; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000139:chemically induced*; D017769:Ulnar Nerve Compression Syndromes / Q000188:drug therapy
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D000077555:Methylprednisolone Acetate; C011175:betamethasone-17,21-dipropionate; D001623:Betamethasone; D008775:Methylprednisolone