title: Squamous cell carcinoma of the prostate: 2 cases of a rare malignancy and review of the literature.
abstract: Primary squamous cell carcinoma of the prostate is an extremely uncommon malignancy, accounting for less than 1% of all prostatic cancers. We report on 2 patients with primary squamous cell carcinoma of the prostate: 1 with organ-confined disease and 1 with metastatic disease. Both patients presented with urinary obstructive symptoms and carcinoma was not suspected on digital rectal examination. Serum acid phosphatase and prostate specific antigen levels were normal. From a review of the literature and our 2 cases it is apparent that squamous cell carcinoma of the prostate is biologically more aggressive than adenocarcinoma.
authors.affiliation: Department of Surgery, Duke University School of Medicine, Durham, North Carolina.
authors.forename: N A
authors.initials: NA
authors.lastname: Little
authors.forename: J S
authors.initials: JS
authors.lastname: Wiener
authors.forename: P J
authors.initials: PJ
authors.lastname: Walther
authors.forename: D F
authors.initials: DF
authors.lastname: Paulson
authors.forename: E E
authors.initials: EE
authors.lastname: Anderson
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology*