title: The role of vacuolar digestive system in preventing cadmium poisoning in Acanthamoeba castellanii.
abstract: Constituents showing cadmium affinity were found in digestive residues of the vacuolar digestive system in Acanthamoeba. Cadmium was detected by means of X-ray analysis in complexes appearing both in residues included within the digestive vacuoles and in those egested outside the cell. The digestive vacuolar system in Acanthamoeba castellanii is characterized by a particularly high turnover rate (4). Confronted with this fact, results of the present study suggest that the system is able to egest rapidly the ligand-bound cadmium. In this way protects the amoeba against serious toxic effects of the Cd-polluted environment.
authors.affiliation: Department of Cell Biology, Nencki Institute of Experimental Biology, Warsaw, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Przełecka
authors.forename: A M
authors.initials: AM
authors.lastname: Kluska
authors.forename: M
authors.initials: M
authors.lastname: Zwierzyk
mesh_terms: D000048:Acanthamoeba / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D002104:Cadmium / Q000032:analysis; D002105:Cadmium Poisoning / Q000517:prevention & control*; D004068:Digestive System Physiological Phenomena; D004577:Electron Probe Microanalysis; D014617:Vacuoles / Q000502:physiology*
chemical_list: D002104:Cadmium