The analgesic efficacy of diclofenac dispersible and ibuprofen in postoperative pain after dental extraction.
We have compared single oral doses of drinkable diclofenac dispersible (50 mg) with ibuprofen (400 mg) and placebo in a randomized, double-blind, parallel-group trial in 127 adults complaining of at least moderately severe pain after removal of an impacted third molar. Within 40 min both diclofenac and ibuprofen produced significant pain relief that persisted for 6 h. There were no differences between diclofenac and ibuprofen in analgesic efficacy.
Ahlström
U
U
Department of Oral Surgery, Institute of Postgraduate Dental Education, Jönköping, Sweden.
Bakshi
R
R
Nilsson
P
P
Wåhlander
L
L
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000698:Analgesia; D004008:Diclofenac / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D008297:Male; D008964:Molar, Third; D010149:Postoperative Pain / Q000188:drug therapy*; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery
D004008:Diclofenac; D007052:Ibuprofen