title: Localization of the alpha-S2-casein gene (CASAS2) to the homoeologous cattle, sheep, and goat chromosomes 4 by in situ hybridization.
abstract: The alpha-S2-casein gene (CASAS2) has been mapped to the homoeologous cattle, sheep, and goat chromosomes 4 and to the long arm of a bovine chromosome translocation, t(4;8), using nonradioactive in situ hybridization and simultaneous fluorescent R-banding. The t(4;8) has been characterized by GTG-, GBG-, and RBG-banding and by silver staining of nucleolus organizer regions. These results confirm the previous (ISCNDA, 1989) localization of the casein gene group to chromosome 4 of cattle, sheep, and goats. We propose that the discrepancy between our results and earlier assignments of the casein gene group to chromosome 6 of cattle and sheep can be explained by the fact that the chromosome identified as No. 6 in the Reading Conference (1976) report was renamed chromosome 4 in the ISCNDA (1989) standardized karyotype of both species.
authors.affiliation: Laboratoire de Génétique Biochimique et de Cytogénétique, INRA-CRJ, Jouy-en-Josas, France.
authors.forename: H
authors.initials: H
authors.lastname: Hayes
authors.forename: E
authors.initials: E
authors.lastname: Petit
authors.forename: C
authors.initials: C
authors.lastname: Bouniol
authors.forename: P
authors.initials: P
authors.lastname: Popescu
mesh_terms: D000818:Animals; D002364:Caseins / Q000235:genetics*; D002417:Cattle; D002478:Cells, Cultured; D002871:Chromosome Banding; D002874:Chromosome Mapping; D006041:Goats; D017403:In Situ Hybridization; D007621:Karyotyping; D012756:Sheep; D014178:Translocation, Genetic
chemical_list: D002364:Caseins