Electron microscopic identification of parvovirus virions in erythroid and granulocytic-line cells in a patient with human parvovirus B19 induced pancytopenia.
In this short report we describe a patient with human parvovirus B19 (HPV B19)-induced transient pancytopenia. Parvovirus virions were seen by electron microscopy in both erythroid and granulocytic precursors. Erythroid cells are not the only targets in these cases. We draw attention to this disorder so that physicians involved with hematological disorders and transplantation be more aware of this infection.
Millá
F
F
Haematology-Haemotherapy Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Feliu
E
E
Ribera
J M
JM
Juncà
J
J
Flores
A
A
Vidal
J
J
Zarco
M A
MA
Masat
T
T
D000328:Adult; D016731:Erythema Infectiosum / Q000150:complications / Q000175:diagnosis*; D004912:Erythrocytes / Q000382:microbiology / Q000648:ultrastructure; D005260:Female; D006098:Granulocytes / Q000382:microbiology / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D010198:Pancytopenia / Q000382:microbiology* / Q000473:pathology; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D014771:Virion / Q000302:isolation & purification