title: Orbital decompression for preservation of vision in Graves' ophthalmopathy.
abstract: Graves' ophthalmopathy (thyroid eye disease) can result in progressive visual loss. The University of Washington (Seattle) experience in orbital decompression was reviewed for the years 1983 through 1990 to determine overall safety and outcome. Twenty patients underwent transantral decompression of 36 orbits for either steroid therapy failure, steroid therapy intolerance, or recurrence of optic neuropathy with tapering of the steroid therapy. Decompression successfully improved visual function in 33 of the orbits (92%) and a second decompression procedure was successful in another two (5%) of the orbits (6%). There were no major complications or cases of decreased visual function. Diplopia, present preoperatively in 17 patients (85%), was improved in eight patients (47%) and unchanged in nine patients (53%). However, of the three patients without preoperative diplopia (15%), one had development of new-onset diplopia postoperatively. Transantral decompression of the orbit offers a safe and effective therapeutic modality for vision-threatening Graves' ophthalmopathy.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, University of Washington, Seattle 98195.
authors.forename: D A
authors.initials: DA
authors.lastname: Girod
authors.forename: J C
authors.initials: JC
authors.lastname: Orcutt
authors.forename: C W
authors.initials: CW
authors.lastname: Cummings
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006111:Graves Disease / Q000145:classification / Q000150:complications / Q000601:surgery*; D006785:Hospitals, University; D006801:Humans; D007429:Intraocular Pressure; D016018:Least-Squares Analysis; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000145:classification / Q000150:complications / Q000601:surgery*; D010044:Outpatient Clinics, Hospital; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology; D014792:Visual Acuity; D014861:Washington / Q000453:epidemiology
chemical_list: D000305:Adrenal Cortex Hormones