title: Anorectal function of children with neurological problems. I: Spina bifida.
abstract: Anorectal function was assessed with anorectal manometry in 45 children with spina bifida (21 girls and 24 boys, mean age 11 1/2 years). 24 enuretic children served as controls. The pressure in the first and second centimeters of the anal canal was lower among index children than controls and also lower among those with high spinal lesions compared with those with low lesions. Rectal activity (rectal sensation and trace appearance) during rectal distension appeared to be reduced among index children; sensation was particularly poor among those with high spinal lesions. Manometry may be useful in children with spina bifida as it provides a clearer understanding of sphincter function and leads to a more rational approach to the management of bowel problems.
authors.affiliation: United Medical School, London.
authors.forename: U
authors.initials: U
authors.lastname: Agnarsson
authors.forename: C
authors.initials: C
authors.lastname: Warde
authors.forename: G
authors.initials: G
authors.lastname: McCarthy
authors.forename: G S
authors.initials: GS
authors.lastname: Clayden
authors.forename: N
authors.initials: N
authors.lastname: Evans
mesh_terms: D000293:Adolescent; D001003:Anal Canal / Q000503:physiopathology; D001004:Anus Diseases / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008365:Manometry; D012002:Rectal Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D012007:Rectum / Q000294:innervation / Q000503:physiopathology; D012018:Reflex / Q000502:physiology*; D016135:Spinal Dysraphism / Q000150:complications / Q000503:physiopathology*