An assessment of spin-echo rotating-frame imaging for spatially localized determination of short T2 relaxation times in vivo.
The rotating frame of localized spectroscopy can be augmented by the inclusion of a refocusing pulse to enable the measurement of T2 relaxation times. This technique is particularly appropriate for determining short relaxation parameters due to the absence of time consuming switched B(omicron) field gradients. We have evaluated the accuracy of this protocol by measuring localized T2s in the range of 1 to 20 ms. Preliminary data obtained from muscle and liver of normal and iron overloaded human subjects are also presented.
Dixon
R M
RM
MRC Biochemical Unit, John Radcliffe Hospital, Oxford, United Kingdom.
Styles
P
P
D008279:Magnetic Resonance Imaging / Q000379:methods*