[An inhibitory analysis of the role of the enterocyte cytoskeleton in the absorption of food substances in the small intestine].
The effect of colchicine and cytochalasin B and D on the process of glucose and plant oil absorption in the small intestine of rats was studied using the light and electron microscopy and biochemical methods. The colchicine and CB, CD action on the elements of enterocytes' apical contractile complex and cytoskeleton inhibited the absorption thus suggesting the major role of endocytosis in the process of nutrients absorption in the small intestine.
Morozov
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Verina
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D000818:Animals; D003078:Colchicine / Q000494:pharmacology; D003571:Cytochalasin B / Q000494:pharmacology; D015638:Cytochalasin D / Q000494:pharmacology; D003599:Cytoskeleton / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D003864:Depression, Chemical; D005947:Glucose / Q000378:metabolism; D007408:Intestinal Absorption / Q000187:drug effects / Q000502:physiology*; D007421:Intestine, Small / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D010938:Plant Oils / Q000493:pharmacokinetics; D051381:Rats; D013997:Time Factors
D010938:Plant Oils; D015638:Cytochalasin D; D003571:Cytochalasin B; D005947:Glucose; D003078:Colchicine