title: Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics.
abstract: 1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during haloperidol decanoate treatment.
authors.affiliation: Laboratory of Biological Psychiatry, Taipei City Psychiatric Center.
authors.forename: W H
authors.initials: WH
authors.lastname: Chang
authors.forename: S K
authors.initials: SK
authors.lastname: Lin
authors.forename: D J
authors.initials: DJ
authors.lastname: Juang
authors.forename: L C
authors.initials: LC
authors.lastname: Chen
authors.forename: C H
authors.initials: CH
authors.lastname: Yang
authors.forename: W H
authors.initials: WH
authors.lastname: Hu
authors.forename: C P
authors.initials: CP
authors.lastname: Chien
authors.forename: Y F
authors.initials: YF
authors.lastname: Lam
authors.forename: M W
authors.initials: MW
authors.lastname: Jann
mesh_terms: D000284:Administration, Oral; D000328:Adult; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D012559:Schizophrenia / Q000188:drug therapy*
chemical_list: C040692:4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol; C033563:haloperidol decanoate; D006220:Haloperidol