title: Tridimensional Personality Questionnaire and serotonin in bulimia nervosa.
abstract: To determine the relationship between Tridimensional Personality Questionnaire (TPQ) scales and bulimia nervosa, TPQ scores of 27 bulimic women, age range 21-59, were compared with values for an age-matched sample of 128 normal control women drawn from the national norming sample by Przybeck. Scores for Novelty Seeking and Harm Avoidance were significantly higher, while scores for Reward Dependence were significantly lower for the bulimic women. A stepwise regression model of severity of purging on TPQ selected Novelty Seeking and a composite depression score, with Novelty Seeking being the stronger of the two predictors. Whole blood serotonin levels did not relate to TPQ scores or to purging frequency.
authors.affiliation: Dept. of Psychiatry, U.T. Southwestern Medical Center, Dallas 75235-9070.
authors.forename: D A
authors.initials: DA
authors.lastname: Waller
authors.forename: C M
authors.initials: CM
authors.lastname: Gullion
authors.forename: F
authors.initials: F
authors.lastname: Petty
authors.forename: B W
authors.initials: BW
authors.lastname: Hardy
authors.forename: M V
authors.initials: MV
authors.lastname: Murdock
authors.forename: A J
authors.initials: AJ
authors.lastname: Rush
mesh_terms: D000328:Adult; D001143:Arousal / Q000187:drug effects; D002032:Bulimia / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010555:Personality Inventory / Q000706:statistics & numerical data*; D011594:Psychometrics; D012701:Serotonin / Q000097:blood*
chemical_list: D005473:Fluoxetine; D012701:Serotonin