The renin-angiotensin system and blood pressure regulation during infancy and childhood.
The renin-angiotensin system plays multiple roles in the maintenance of normal blood pressure and renal function. The balance and integration of these roles change during development in ways that we do not yet fully understand. This article reviews the ways in which the renin-angiotensin system maintains normal cardiovascular homeostasis during development and its participation in physiologic and biochemical events.
Guillery
E N
EN
Department of Pediatrics, University of Iowa, Iowa City.
Robillard
J E
JE
D000375:Aging / Q000502:physiology*; D000595:Amino Acid Sequence; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D005314:Embryonic and Fetal Development / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D007223:Infant; D008969:Molecular Sequence Data; D012084:Renin-Angiotensin System / Q000502:physiology*
D000806:Angiotensin-Converting Enzyme Inhibitors