[Radiosensitizing effect of hyperthermia (41.5C, 30 min) in stem cells of mouse spermatogenic epithelium].
Mouse testes preheated up to 41.5 degrees C for 30 min exhibit an increased radiosensitivity of testis epithelium stem cells. High death rate is described by a shift (by approximately 4 Gy) in the "dose-response" curve to the Abscissa left. The DMF value for hyperthermia depends on the cell survival rate, at which calculations are made, and varies from 2.1 to 1.4 within the range under study.
Lebedeva
T V
TV
Konopliannikova
O A
OA
D000818:Animals; D002470:Cell Survival; D004307:Dose-Response Relationship, Radiation; D004847:Epithelial Cells; D004848:Epithelium / Q000528:radiation effects; D006358:Hot Temperature; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011836:Radiation Tolerance; D013234:Stem Cells / Q000166:cytology / Q000528:radiation effects*; D013737:Testis / Q000166:cytology / Q000528:radiation effects*; D013997:Time Factors