title: Recombinant bovine and porcine somatotropin: safety and benefits of these biotechnologies.
abstract: This article reviews the literature about the safety and benefits of two recombinantly derived proteins, bovine somatotropin (bST) and porcine somatotropin (pST), that likely will be used in animal agriculture in the future. When administered to dairy cows, bST increases milk production per cow approximately 15% to 20% and improves productive efficiency approximately 10%. Administration of pST to growing pigs reduces carcass fat content by as much as 70% to 80% and improves productive efficiency 15% to 35%. Because meat is a major source of total fat and saturated fatty acids in the diets of human beings, pST will allow consumers to include leaner, more nutrient-dense pork in their diets and still meet current dietary guidelines. Although these biotechnologies have not yet received regulatory approval from the Food and Drug Administration (FDA) for commercial use, information published by the FDA, the National Institutes of Health, the US Congress Office of Technology Assessment, and the American Academy of Pediatrics, as well as an extensive body of scientific evidence, indicate that these products are safe for the consumer. Nonetheless, it is important that consumers understand the benefits and safety of these biotechnologies. Dietitians can play an important role in providing information to consumers about the safety and benefits of bST and pST.
authors.affiliation: Department of Dairy and Animal Science, Pennsylvania State University, University Park 16802.
authors.forename: T D
authors.initials: TD
authors.lastname: Etherton
authors.forename: P M
authors.initials: PM
authors.lastname: Kris-Etherton
authors.forename: E W
authors.initials: EW
authors.lastname: Mills
mesh_terms: D000818:Animals; D002417:Cattle; D003257:Consumer Product Safety; D004041:Dietary Fats / Q000008:administration & dosage; D005506:Food Contamination; D013006:Growth Hormone / Q000009:adverse effects / Q000494:pharmacology*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008460:Meat / Q000592:standards*; D008892:Milk / Q000592:standards*; D011994:Recombinant Proteins / Q000009:adverse effects / Q000494:pharmacology; D013552:Swine
chemical_list: D004041:Dietary Fats; D011994:Recombinant Proteins; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone