title: [Chest pain of esophageal origin in patients with a normal coronary angiogram and ergonovine-induced coronary spasm].
abstract: In order to differentiate the cardiac or oesophageal origin of chest pain, 55 patients with chest pain, normal coronary arteriogram and normal left ventricular function, were studied. Patients were evaluated with ergonovine test to induce coronary artery spasm and oesophageal function study (including basal manometry in all cases, ClH acid instillation in 53, manometry during ClH instillation in 32 and edrophonium test in 9). There was coronary artery spasm following ergonovine test in 8 patients (group 1) and negative results in 47 (group 2). There was oesophageal disfunction in 50% patients in group 1 and in 62% patients in group 2 (p = NS). The incidence of motor disorders or chest pain following acid instillation was not significatively different in both groups. Nevertheless, in group 1 a tendency to a greater incidence of oesophageal spasm was observed while in group 2 unspecified disorders were more frequent. Thus, in patients with chest pain and normal coronary arteriogram, we always must discard coronary artery spasm and oesophageal disfunction, because, due to a probably common cause, association between both disorders is frequent.
authors.affiliation: Servicio de Cardiología (Unidad de Hemodinámica), Hospital Universitario Virgen del Rocío, Sevilla.
authors.forename: J A
authors.initials: JA
authors.lastname: Fournier
authors.forename: L
authors.initials: L
authors.lastname: Trujillo
authors.forename: M C
authors.initials: MC
authors.lastname: Hernández
authors.forename: J A
authors.initials: JA
authors.lastname: Fernández-Cortacero
mesh_terms: D000328:Adult; D000368:Aged; D006328:Cardiac Catheterization; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D004874:Ergonovine / Q000031:analogs & derivatives*; D015155:Esophageal Spasm, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D004947:Esophagus / Q000503:physiopathology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged
chemical_list: D004874:Ergonovine