title: Exchange arthroplasty for infected knee replacements. A new two-stage method.
abstract: We report a series of 17 exchange arthroplasties for infected knee prostheses, ten one-stage and seven two-stage procedures. The method proved successful in controlling infection and restoring function. In two-stage exchanges the interval between the stages was managed by using a prosthesis as a spacer, and acrylic cement beads containing the appropriate antibiotic to provide high local concentrations. Three one-stage procedures had recurrence of infection, but were successfully treated by further exchange operations. All patients had satisfactory function and there have been no serious complications. We recommend this modified two-stage technique for the management of infected knee arthroplasties.
authors.affiliation: Northern General Hospital, Sheffield, England.
authors.forename: I R
authors.initials: IR
authors.lastname: Scott
authors.forename: I
authors.initials: I
authors.lastname: Stockley
authors.forename: C J
authors.initials: CJ
authors.lastname: Getty
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001178:Arthroplasty / Q000379:methods; D005260:Female; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000601:surgery*; D012086:Reoperation
chemical_list: D000900:Anti-Bacterial Agents