Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate): a potent selective 5-phosphatase inhibitor.
Kozikowski
A P
AP
Mayo Foundation for Medical Education and Research, Jacksonville, Florida 32224.
Ognyanov
V I
VI
Chen
C
C
Fauq
A H
AH
Safrany
S T
ST
Wilcox
R A
RA
Nahorski
S R
SR
D015220:Calcium Channels / Q000378:metabolism; D003510:Cyclohexanes / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D015544:Inositol 1,4,5-Trisphosphate / Q000031:analogs & derivatives*; D053496:Inositol 1,4,5-Trisphosphate Receptors; D008698:Mesylates / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D015394:Molecular Structure; D010749:Phosphoprotein Phosphatases / Q000037:antagonists & inhibitors*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D013329:Structure-Activity Relationship
D015220:Calcium Channels; D003510:Cyclohexanes; D053496:Inositol 1,4,5-Trisphosphate Receptors; D008698:Mesylates; D018160:Receptors, Cytoplasmic and Nuclear; C083633:cyclohexane-1,2,4-tris(methylenesulfonate); D015544:Inositol 1,4,5-Trisphosphate; D010749:Phosphoprotein Phosphatases