[Prevention of IOP rise following laser iridectomy with topical timolol and indomethacin].
Double-masked study on 40 eyes (40 patients) of primary angle-closure glaucoma demonstrated that topical timolol and indomethacin prevented the IOP rise following combined argon and Nd:YAG laser iridectomy. A combination of the 2 drugs was especially effective in that the number of patients who would have an IOP increase over 1.33 kPa (1 kPa = 7.5 mmHg) above the baseline was reduced by 80%. The mechanism of IOP rise following iridectomy and its prevention were discussed.
Peng
D W
DW
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou.
D005260:Female; D015812:Glaucoma, Angle-Closure / Q000601:surgery*; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage; D007498:Iris / Q000601:surgery; D053685:Laser Therapy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000209:etiology / Q000517:prevention & control*; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*; D011292:Premedication; D011446:Prospective Studies; D013999:Timolol / Q000008:administration & dosage*
D009883:Ophthalmic Solutions; D013999:Timolol; D007213:Indomethacin