title: Chemotactic signalling in Rhodobacter sphaeroides requires metabolism of attractants.
abstract: Rhodobacter sphaeroides showed chemotaxis towards L-alanine but not towards the analog 2-aminoisobutyrate. 2-Aminoisobutyrate and alanine were shown to share a common transport system, but 2-aminoisobutyrate was not metabolized. Chemotaxis towards alanine was inhibited by structurally unrelated metabolites, suggesting cross-inhibition by common metabolic intermediates.
authors.affiliation: Department of Microbiology, University of Reading, Whiteknights, United Kingdom.
authors.forename: P S
authors.initials: PS
authors.lastname: Poole
authors.forename: M J
authors.initials: MJ
authors.lastname: Smith
authors.forename: J P
authors.initials: JP
authors.lastname: Armitage
mesh_terms: D000409:Alanine / Q000378:metabolism* / Q000494:pharmacology; D000621:Aminoisobutyric Acids / Q000378:metabolism* / Q000494:pharmacology; D001692:Biological Transport; D002245:Carbon Dioxide / Q000378:metabolism; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone / Q000494:pharmacology; D002450:Cell Communication; D002633:Chemotaxis / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D012242:Rhodobacter sphaeroides / Q000187:drug effects / Q000378:metabolism*
chemical_list: D000621:Aminoisobutyric Acids; D002245:Carbon Dioxide; C100049:2-aminoisobutyric acid; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone; D000409:Alanine