Localization of the alpha-S2-casein gene (CASAS2) to the homoeologous cattle, sheep, and goat chromosomes 4 by in situ hybridization.
The alpha-S2-casein gene (CASAS2) has been mapped to the homoeologous cattle, sheep, and goat chromosomes 4 and to the long arm of a bovine chromosome translocation, t(4;8), using nonradioactive in situ hybridization and simultaneous fluorescent R-banding. The t(4;8) has been characterized by GTG-, GBG-, and RBG-banding and by silver staining of nucleolus organizer regions. These results confirm the previous (ISCNDA, 1989) localization of the casein gene group to chromosome 4 of cattle, sheep, and goats. We propose that the discrepancy between our results and earlier assignments of the casein gene group to chromosome 6 of cattle and sheep can be explained by the fact that the chromosome identified as No. 6 in the Reading Conference (1976) report was renamed chromosome 4 in the ISCNDA (1989) standardized karyotype of both species.
Hayes
H
H
Laboratoire de Génétique Biochimique et de Cytogénétique, INRA-CRJ, Jouy-en-Josas, France.
Petit
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E
Bouniol
C
C
Popescu
P
P
D000818:Animals; D002364:Caseins / Q000235:genetics*; D002417:Cattle; D002478:Cells, Cultured; D002871:Chromosome Banding; D002874:Chromosome Mapping; D006041:Goats; D017403:In Situ Hybridization; D007621:Karyotyping; D012756:Sheep; D014178:Translocation, Genetic
D002364:Caseins