Periodontal disease and dental caries in relation to primary IgG subclass and other humoral immunodeficiencies.
22 females and 3 males with primary hypogammaglobulinaemia (n = 6) or IgG subclass deficiencies with (n = 3) or without (n = 16) concomitant IgA deficiency were examined for periodontal disease and dental caries. Only 1 patient showed more tooth loss than that found in the normal Swedish population. 1 patient demonstrated advanced periodontal disease. No patient exhibited more severe dental caries than that of comparable normal Swedes. Microbiological samples from periodontal pockets and saliva showed recovery of potential periodontopathic and cariogenic bacteria within normal ranges. This study could not support the notion that immunodeficient subjects exhibit an increased risk of developing periodontal disease or dental caries.
Dahlén
G
G
Department of Oral Microbiology, Faculty of Odontology, University of Göteborg, Sweden.
Björkander
J
J
Gahnberg
L
L
Slots
J
J
Hanson
L A
LA
D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications / Q000276:immunology; D000368:Aged; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D001439:Bacteroides / Q000302:isolation & purification; D002206:Capnocytophaga / Q000302:isolation & purification; D002648:Child; D003731:Dental Caries / Q000150:complications*; D005260:Female; D006801:Humans; D017098:IgA Deficiency / Q000150:complications* / Q000276:immunology; D017099:IgG Deficiency / Q000150:complications* / Q000276:immunology; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis / Q000145:classification*; D007778:Lactobacillus / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000150:complications; D010510:Periodontal Diseases / Q000150:complications* / Q000382:microbiology; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000382:microbiology; D012463:Saliva / Q000737:chemistry / Q000276:immunology; D013295:Streptococcus mutans / Q000302:isolation & purification; D016968:Wolinella / Q000302:isolation & purification
D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G