title: Factor XI: structure-function relationships utilizing monoclonal antibodies protein modification, computational chemistry, and rational synthetic peptide design.
authors.affiliation: Department of Medicine, Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
authors.forename: P N
authors.initials: PN
authors.lastname: Walsh
authors.forename: F A
authors.initials: FA
authors.lastname: Baglia
authors.forename: B A
authors.initials: BA
authors.lastname: Jameson
mesh_terms: D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal; D000937:Antigen-Antibody Reactions; D001345:Autoradiography / Q000379:methods; D003488:Cyanogen Bromide; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D005172:Factor XI / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D015945:Factor XIa / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D007074:Immunoglobulin G / Q000145:classification / Q000378:metabolism; D007202:Indicators and Reagents; D007457:Iodine Radioisotopes; D007700:Kinetics; D046911:Macromolecular Substances; D008958:Models, Molecular; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010446:Peptide Fragments / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification; D011487:Protein Conformation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D011863:Radioimmunoassay / Q000379:methods; D011865:Radioisotope Dilution Technique; D014316:Tritium
chemical_list: D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D007202:Indicators and Reagents; D007457:Iodine Radioisotopes; D046911:Macromolecular Substances; D010446:Peptide Fragments; D014316:Tritium; D005172:Factor XI; D015945:Factor XIa; D003488:Cyanogen Bromide