title: A variant family of mouse minor satellite located on the centromeric region of chromosome 2.
abstract: A variant sequence of minor satellite that exhibits a polymorphism in strains and a subspecies of the mouse by pulsed-field gel analysis has been cloned. A segregation study using intrasubspecific backcross mice reveals that the variant maps to the centromeric region of chromosome 2. A long-range physical analysis of the region shows that the variant family is probably located between the proximal telomere and the major satellite. The sequence probe provides an important marker of the chromosome 2-specific centromere.
authors.affiliation: First Department of Biochemistry, Niigata University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hayashi
authors.forename: H
authors.initials: H
authors.lastname: Ohtsuka
authors.forename: K
authors.initials: K
authors.lastname: Kuwabara
authors.forename: Y
authors.initials: Y
authors.lastname: Mafune
authors.forename: N
authors.initials: N
authors.lastname: Miyashita
authors.forename: K
authors.initials: K
authors.lastname: Moriwaki
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: R
authors.initials: R
authors.lastname: Kominami
mesh_terms: D000818:Animals; D001483:Base Sequence; D002503:Centromere / Q000502:physiology* / Q000648:ultrastructure; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004276:DNA, Satellite / Q000235:genetics*; D015247:Deoxyribonuclease HindIII; D005260:Female; D014644:Genetic Variation; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics*; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D011110:Polymorphism, Genetic; D015183:Restriction Mapping
chemical_list: D004276:DNA, Satellite; D015345:Oligonucleotide Probes; D015247:Deoxyribonuclease HindIII