Hypometabolic and hypothermic factors from small intestine of hibernating ground squirrels (Citellus undulatus).
Low molecular mass components of the acetic acid extract from the small intestine of hibernating ground squirrels (Citellus undulatus) produced a decrease in oxygen consumption and body temperature of white mice and a dose-dependent delay in embryonic development of sea urchin (Strongylocentrotus intermedius). Equivalent doses of low molecular mass components obtained by the same method from active (summer) animals did not have such an effect.
Kramarova
L I
LI
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region.
Kolaeva
S G
SG
Bronnikov
G E
GE
Ignatiev
A D
AD
Krasts
I V
IV
D000818:Animals; D001685:Biological Factors / Q000032:analysis / Q000494:pharmacology*; D001831:Body Temperature / Q000187:drug effects* / Q000502:physiology; D002845:Chromatography; D005260:Female; D006605:Hibernation / Q000502:physiology*; D007421:Intestine, Small / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D008297:Male; D051379:Mice; D008970:Molecular Weight; D012589:Sciuridae / Q000378:metabolism / Q000502:physiology*; D012617:Sea Urchins; D014020:Tissue Extracts / Q000032:analysis / Q000494:pharmacology; D015053:Zygote / Q000187:drug effects
D001685:Biological Factors; D014020:Tissue Extracts