title: Chemiluminescence immunoassay to detect anti-HTLV-I antibodies.
abstract: A fully automated chemiluminescence immunoassay was developed for the detection of antibodies to HTLV-I. We used partially purified viral antigens coated on small polystyrene beads together with acridinium ester-labeled anti-human immunoglobulin G mouse immunoglobulin G in this method. A good agreement was observed between our proposed method, the indirect immunofluorescence assay, the particle-agglutination test and the enzyme immunoassay. This new method, which is simple, sensitive, specific and rapid, should be useful for mass screening of anti-HTLV-I antibodies.
authors.affiliation: Blood Transfusion Service, School of Medicine, Nagasaki University.
authors.forename: S
authors.initials: S
authors.lastname: Kamihira
authors.forename: S
authors.initials: S
authors.lastname: Nakashima
authors.forename: S
authors.initials: S
authors.lastname: Saitoh
authors.forename: M
authors.initials: M
authors.lastname: Kawamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Kawashima
authors.forename: M
authors.initials: M
authors.lastname: Shimamoto
mesh_terms: D015481:HTLV-I Antibodies / Q000032:analysis*; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008163:Luminescent Measurements
chemical_list: D015481:HTLV-I Antibodies