[Enhancing effect of jian pi jin dan on immune functions of normal and cyclophosphamide induced immunosuppressed mice].
By means of normal and cyclophosphamide (CY) injected NIH mice, the effect of Jian Pi Jin Dan on immuno-modulation was studied which could treat the "Gan" disease effectively in TCM.


RESULTS
Markedly improved the level of serum lysozyme, enhance the phagocytosis of abdominal macrophage. The proliferation of spleen T, B cells, the production of interleukin-1 (IL-1) by macrophage and of interleukin-2 (IL-2) by T cells in normal and CY injected mice were also enhanced. Furthermore, it was able to restore the weight, spleen and thymus index of CY injected mice. This prescription can not only reinforce Spleen, but also regulate Liver, complying to the children's physiological and pathological characteristics.
Fan
Y P
YP
Beijing College of TCM.
D000818:Animals; D003520:Cyclophosphamide; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D016867:Immunocompromised Host / Q000187:drug effects*; D007375:Interleukin-1 / Q000096:biosynthesis; D007376:Interleukin-2 / Q000096:biosynthesis; D051379:Mice; D009929:Organ Size / Q000187:drug effects; D010587:Phagocytosis / Q000187:drug effects*; D013154:Spleen / Q000033:anatomy & histology; D013601:T-Lymphocytes / Q000187:drug effects*; D013950:Thymus Gland / Q000033:anatomy & histology
D004365:Drugs, Chinese Herbal; D007375:Interleukin-1; D007376:Interleukin-2; D003520:Cyclophosphamide