title: The effect of lead, gold, and silver backings on dose near 125I seeds.
abstract: Brachytherapy for ocular melanoma uses 125I seeds backed by a gold shield. Conflicting results are reported in the literature on the effect of the gold on dose close to the seeds. In this work, a small lucite jig was constructed such that the seed-to-detector separation remained fixed as high-Z materials of lead, silver, and gold were moved in and out of position behind the seed. The jig was clamped in place in the water filled tank of a beam scanning system. The response of two p-type silicon diodes was measured at several distances from the seed with and without the high-Z backings. The response with the high-Z backing relative to water, found to be the same for each diode and the same for lead and gold, decreased from about 1.01 at 1.5 mm to about 0.92 at 20 mm. It has been suggested in the literature that L-shell fluorescent x rays of approximately 10 keV from the gold backing might contribute significantly to the dose within 7 mm of the seed. To test this, the response with the gold backing relative to water was measured with an aluminum cap of 1-mm wall thickness covering the diode. The cap transmits about 70% of the 125I influence but is essentially infinitely thick to 10-keV photons. The relative response (gold/water) was the same with and without the cap showing that the contribution of 10-keV x rays is negligible. Compared to water, the silver backing was found to enhance the diode response by about 14% between 5 to 10 mm from the seed.
authors.affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06510.
authors.forename: J A
authors.initials: JA
authors.lastname: Meli
authors.forename: K A
authors.initials: KA
authors.lastname: Motakabbir
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D001918:Brachytherapy / Q000295:instrumentation*; D005069:Evaluation Studies as Topic; D005134:Eye Neoplasms / Q000532:radiotherapy*; D006046:Gold; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D007854:Lead; D008545:Melanoma / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012542:Scattering, Radiation; D012834:Silver
chemical_list: D007457:Iodine Radioisotopes; D007854:Lead; D012834:Silver; D006046:Gold