title: A clinical comparison of glass ionomer (polyalkenoate) and silver amalgam restorations in the treatment of Class 5 caries in xerostomic head and neck cancer patients.
abstract: Fifty-four pairs of restorations (one glass ionomer and the other amalgam) were placed in the mouths of 36 xerostomic head and neck cancer patients. Patients were either fluoride users or fluoride nonusers. In patients who used a daily application of a mildly acidic (pH 5.8) sodium fluoride gel, glass-ionomer cements failed and amalgam restorations did not (P < 0.0001). In patients who neglected to use their topical fluoride as directed, glass-ionomer cement restorations did not fail, but amalgam restorations did (P < 0.001). The mean time to restoration loss for both restorative materials was 8.5 months. In severely xerostomic patients these findings were exaggerated.
authors.affiliation: Ontario Cancer Institute Incorporating the Princess Margaret Hospital, Dept. of Dentistry, Toronto, Canada.
authors.forename: R E
authors.initials: RE
authors.lastname: Wood
authors.forename: W G
authors.initials: WG
authors.lastname: Maxymiw
authors.forename: D
authors.initials: D
authors.lastname: McComb
mesh_terms: D016722:Cermet Cements; D016371:Cranial Irradiation / Q000009:adverse effects*; D003723:Dental Amalgam; D017742:Dental Care for Chronically Ill; D003731:Dental Caries / Q000209:etiology / Q000628:therapy*; D003793:Dental Restoration, Permanent / Q000379:methods*; D005460:Fluorides, Topical / Q000627:therapeutic use; D005899:Glass Ionomer Cements; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D008298:Maleates; D018030:Silver Compounds; D014987:Xerostomia / Q000150:complications / Q000209:etiology
chemical_list: D016722:Cermet Cements; D005460:Fluorides, Topical; D005899:Glass Ionomer Cements; D008298:Maleates; D018030:Silver Compounds; C067445:Chelon Silver; D003723:Dental Amalgam; C040964:Ketac-Fil