title: Solitary fibrosing paraspinal plaque: solitary morphoea profunda?
abstract: Solitary morphoea profunda is a recently described morphological variant of localized scleroderma. Two of the five reported patients had a solitary fibrotic plaque in the paraspinal region. We report a 16-year-old boy with a solitary fibrotic paraspinal plaque which, on histological examination, showed dermal and subcutaneous sclerosis, with a polymorphous infiltrate including plasma cells and eosinophils. Laboratory tests were either negative or normal, except for mild peripheral blood eosinophilia. Antinuclear antibodies were not detected, and the patient had no evidence of Borrelia infection. Magnetic resonance imaging (MRI) showed that the process involved the subcutaneous tissue, but did not extend to the underlying bone. As half of the patients with this entity (three of six) now described have had a solitary fibrotic plaque in a paraspinal location, we suggest that it may be premature to classify all these cases as being a variant of morphoea. We propose the use of the descriptive term solitary fibrosing paraspinal plaque, until the aetiology or aetiologies of this condition are better understood.
authors.affiliation: University of Miami School of Medicine, Department of Dermatology and Cutaneous Surgery, FL 33136.
authors.forename: R S
authors.initials: RS
authors.lastname: Kirsner
authors.forename: J B
authors.initials: JB
authors.lastname: Pardes
authors.forename: V
authors.initials: V
authors.lastname: Falanga
mesh_terms: D000293:Adolescent; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography; D012594:Scleroderma, Localized / Q000000981:diagnostic imaging / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D013131:Spine / Q000000981:diagnostic imaging