Localization of indoleamine 2,3-dioxygenase gene (INDO) to chromosome 8p12-->p11 by fluorescent in situ hybridization.
Indolamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase are two enzymes that degrade tryptophan to N-formylkynurenine. The gene (TDO2) for tryptophane 2,3-dioxygenase has been localized to 4q31-->32. We now report localization of INDO (the gene encoding indolamine 2,3-dioxygenase) by fluorescent in situ hybridization to 8p12-->p11.
Najfeld
V
V
Tumor Cytogenetics Laboratory, Mount Sinai Medical Center, New York, NY 10029.
Menninger
J
J
Muhleman
D
D
Comings
D E
DE
Gupta
S L
SL
D002898:Chromosomes, Human, Pair 8; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D014366:Tryptophan Oxygenase / Q000235:genetics*
D014366:Tryptophan Oxygenase