Modulation of non-specific immunity by hippocampal stimulation.
Rats subjected to electrical stimulation of hippocampus (30 min/day for 4 days) showed an increase in the neutrophils in the peripheral blood when compared to sham (P < 0.01) and controls (P < 0.001). They also showed a significant decrease in lymphocytes, when compared to control rats (P < 0.001). Both sham and stimulated animals showed a significant decrease in total white blood cell count when compared to controls (P < 0.001). The phagocytic index of stimulated animals showed a significant increase from control (P < 0.001) and sham (P < 0.001). In addition, the stimulated animals showed a significant (P < 0.001) decrease in plasma corticosterone level when compared to sham and controls.
Devi
R S
RS
Department of Physiology, Dr. A.L.M.P.G. Institute of Basic Medical Sciences, University of Madras, Taramani, India.
Namasivayam
A
A
Prabhakaran
K
K
D000818:Animals; D001772:Blood Cell Count; D004558:Electric Stimulation; D006624:Hippocampus / Q000276:immunology / Q000502:physiology*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology; D008297:Male; D009504:Neutrophils / Q000166:cytology / Q000276:immunology; D010587:Phagocytosis; D051381:Rats; D017208:Rats, Wistar