title: Pectoralis major muscle transposition: an adjunct to laryngeal preservation in severe chondroradionecrosis.
abstract: Radiation-induced chondronecrosis of the larynx in early glottic cancer is a rare but serious complication, sometimes requiring total laryngectomy. We describe two patients who developed the major complication of chondroradionecrosis of the larynx 11 and 18 years after completion of radiotherapy. Both cases underwent excision of the overlying skin and of all infected and devitalized thyroid cartilage, followed by pectoralis major muscle transposition and split thickness skin grafting. This procedure resulted in a preservation of all laryngeal functions and also an acceptable cosmetic outcome.
authors.affiliation: Department of ENT/Head and Neck Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Huis, Amsterdam.
authors.forename: A J
authors.initials: AJ
authors.lastname: Balm
authors.forename: F J
authors.initials: FJ
authors.lastname: Hilgers
authors.forename: G
authors.initials: G
authors.lastname: Baris
authors.forename: R B
authors.initials: RB
authors.lastname: Keus
mesh_terms: D000328:Adult; D006801:Humans; D007817:Laryngeal Cartilages / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010369:Pectoralis Muscles / Q000637:transplantation*; D011832:Radiation Injuries / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011878:Radiotherapy / Q000009:adverse effects*; D013524:Surgical Flaps / Q000379:methods* / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed