Lamina propria microinvasion of bladder tumors, incidence on stage allocation (pTa vs pT1): recommended approach. Pathologists of the French Association of Urology Cancer Committee.
A total of 100 bladder cancers posing a diagnostic problem as to invasion of the lamina propria were reevaluated by several pathologists. Agreement was reached in 90 cases after 4 assessments, but no agreement was obtained in the remaining 10 cases. In general, errors were due to overevaluation of microinvasion; only half of the "pT 1 tumors" remained classified as microinvasive pT 1 tumors. We propose that in the assessment presented to the clinician, there should be a clear distinction between pTa tumors with a doubt as to microinvasion, microinvasive pT 1 tumors, and highly invasive pT 1 tumors.
D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging / Q000379:methods*; D015203:Reproducibility of Results; D001743:Urinary Bladder / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*