title: Medial region of the amygdala: involvement in adrenal-steroid-induced salt appetite.
abstract: We report the following observations: first that cell body damage induced by ibotenic acid within the medial region of the amygdala resulted in the abolition of corticosterone-potentiated, aldosterone-induced salt appetite. Sodium depletion-induced salt appetite was not impaired by the lesion, nor was angiotensin-dependent salt appetite via captopril treatment. These results provide evidence that the medial region of the amygdala has a major role in the natriorexigenic effects of the adrenal steroids.
authors.affiliation: Department of Biology, University of Pennsylvania, Philadelphia.
authors.forename: D M
authors.initials: DM
authors.lastname: Zhang
authors.forename: A N
authors.initials: AN
authors.lastname: Epstein
authors.forename: J
authors.initials: J
authors.lastname: Schulkin
mesh_terms: D000450:Aldosterone / Q000494:pharmacology*; D000679:Amygdala / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001066:Appetite / Q000187:drug effects*; D003345:Corticosterone / Q000494:pharmacology*; D007051:Ibotenic Acid; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012965:Sodium Chloride; D012982:Sodium, Dietary; D013238:Stereotaxic Techniques
chemical_list: D012982:Sodium, Dietary; D007051:Ibotenic Acid; D012965:Sodium Chloride; D000450:Aldosterone; D003345:Corticosterone