title: Metastasis of malignant struma ovarii to the cranial vault during pregnancy.
abstract: Malignant struma ovarii is a rare type of ovarian teratoma; only 16 cases with distant metastases have been reported previously. We report an extremely rare case of malignant struma ovarii metastatic to the cranial vault, which developed during pregnancy. A 28-year-old woman in the 26th week of pregnancy, who had undergone resection of an ovarian tumor 3 years previously, noticed a mass in her left frontal region that had enlarged gradually in 6 months. Magnetic resonance imaging revealed a massive extradural tumor growing through the cranium. Under fetal heart monitoring, the patient underwent total resection of the tumor, including the adjacent cranial bone and dura, and a healthy infant was delivered at full term. Pathological examination showed that the tumor was a follicular adenocarcinoma. Because there was no abnormality in the patient's thyroid gland, this tumor was considered to be a metastasis from the ovarian tumor, a malignant struma ovarii, resected 3 years previously. The management of brain tumor during pregnancy is also discussed.
authors.affiliation: Department of Neurosurgery, Mazda Hospital, Hiroshima, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tokuda
authors.forename: T
authors.initials: T
authors.lastname: Hatayama
authors.forename: K
authors.initials: K
authors.lastname: Sakoda
mesh_terms: D000328:Adult; D005260:Female; D005624:Frontal Bone / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000601:surgery*; D011262:Pregnancy Trimester, Second; D012888:Skull Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D013330:Struma Ovarii / Q000473:pathology / Q000556:secondary* / Q000601:surgery