Prostaglandin prophylaxis and bladder function after vaginal hysterectomy: a prospective randomised study.
OBJECTIVE
To assess the efficacy of prostaglandins in enhancing bladder function after vaginal hysterectomy.


METHODS
Prospective randomised study of women who underwent vaginal hysterectomy between November 1989 and August 1990.


METHODS
Sackler School of Medicine Tel Aviv University Medical Center, Department of Obstetrics and Gynaecology 'B'.


METHODS
24 women who underwent vaginal hysterectomy and anterior and posterior colporrhaphy for prolapse.


METHODS
Administration of prostaglandin F2 alpha 5 mg intravesically or E2 3 mg intravaginally versus 100 ml saline intravesically (control) daily, starting on the first postoperative day, until adequate spontaneous voiding was established.


RESULTS
Women receiving PGE2 resumed spontaneous bladder functions earlier, required significantly fewer days catheterisation and had significantly less febrile morbidity compared to women in the control group or PGE2 group.


CONCLUSIONS
Prostaglandins PGE2 intravaginally are beneficial in enhancing functions after vaginal hysterectomy [corrected].
Bergman
A
A
University of Southern California School of Medicine, Women's Hospital, Los Angeles 90033.
Mushket
Y
Y
Gordon
D
D
David
M P
MP
D000328:Adult; D000368:Aged; D015237:Dinoprost / Q000627:therapeutic use*; D015232:Dinoprostone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects*; D008875:Middle Aged; D010570:Pessaries; D011446:Prospective Studies; D001743:Urinary Bladder / Q000503:physiopathology*; D014555:Urination Disorders / Q000503:physiopathology / Q000517:prevention & control*
D015237:Dinoprost; D015232:Dinoprostone