title: [Surgical treatment of thymoma--clinical evaluation].
abstract: Sixty-seven patients with thymoma were surgically treated during the past 19 years in our department. The 5-year, 10-year and 15-year survival rates of total cases with thymomas were 69.2%, 59.6% and 59.6%, respectively. Survival rates of thymoma with MG and without MG were not significantly different. According to clinical stages in Masaoka's classification, there were significant difference between Stage I and Stag III (p < 0.05), Stage I and Stage IV a (p < 0.01), and Stage I and Stage IV b (p < 0.01). We can conclude that complete resection of thymomas lead to better prognosis, and immunochemotherapy using cyclophosphamide, vincristine and OK-432 are effective.
authors.affiliation: Department of Surgery, Kanazawa University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ietsugu
authors.forename: J
authors.initials: J
authors.lastname: Shimizu
authors.forename: S
authors.initials: S
authors.lastname: Murakami
authors.forename: M
authors.initials: M
authors.lastname: Oda
authors.forename: Y
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Tatsuzawa
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
authors.forename: N
authors.initials: N
authors.lastname: Sekido
authors.forename: Y
authors.initials: Y
authors.lastname: Arano
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000008:administration & dosage; D011379:Prognosis; D015996:Survival Rate; D013945:Thymoma / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D013953:Thymus Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D010844:Picibanil; D014750:Vincristine; D003520:Cyclophosphamide