title: Immunological and clinical surveillance in Recklinghausen's neurofibromatosis (NF1).
abstract: Neurofibromatosis evolution is described in relation to the factors that may favour its expansion and immune modifications. NF1 monitorization should employ periodic clinical and immune surveillance. Such an approach would allow the application of immunomodulating treatment (e.g. adapted therapy) only when indicated, thereby reducing its duration and potentiating its efficacy.
authors.affiliation: Department of Orthopaedics, Niguarda Hospital, Milan, Italy.
authors.forename: P L
authors.initials: PL
authors.lastname: Gerosa
authors.forename: C
authors.initials: C
authors.lastname: Vai
authors.forename: L
authors.initials: L
authors.lastname: Bizzozero
authors.forename: A
authors.initials: A
authors.lastname: Fontana
authors.forename: G
authors.initials: G
authors.lastname: Giussani
authors.forename: M
authors.initials: M
authors.lastname: Spinelli
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000097:blood; D003176:Complement C3 / Q000378:metabolism; D005260:Female; D006801:Humans; D007107:Immune System / Q000503:physiopathology; D007136:Immunoglobulins / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000097:blood / Q000276:immunology*
chemical_list: D000936:Antigen-Antibody Complex; D003176:Complement C3; D007136:Immunoglobulins