title: Caroli's disease versus polycystic hepatic disease. Differential diagnosis with Tc-99m DISIDA scintigraphy.
abstract: Four patients with multiple hepatic cysts were studied: two were diagnosed with Caroli's disease (CD) and two with polycystic hepatic disease (PHD). In CD, hepatic scintigraphy with Tc-99m DISIDA showed areas of focally increased radiotracer accumulation that persisted more than 120 minutes, whereas in PHD, areas of focally decreased radiotracer accumulation were observed with normal liver washout and biliary excretion. When multiple hepatic cysts are shown by abdominal echography or CT scan, hepatic scintigraphy with Tc-99m DISIDA should be performed. This examination is safe and noninvasive, and permits differential diagnosis between CD and PHD.
authors.affiliation: Quinta de Salud La Alianza (Sabadell) Barcelona, Hospital Princeps d'España (Hospitalet), Spain.
authors.forename: T
authors.initials: T
authors.lastname: Pinós
authors.forename: X
authors.initials: X
authors.lastname: Xiol
authors.forename: R
authors.initials: R
authors.lastname: Herranz
authors.forename: C
authors.initials: C
authors.lastname: Figueras
authors.forename: I
authors.initials: I
authors.lastname: Catalá
mesh_terms: D000328:Adult; D000368:Aged; D016767:Caroli Disease / Q000000981:diagnostic imaging*; D003560:Cysts / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007098:Imino Acids; D008107:Liver Diseases / Q000000981:diagnostic imaging*; D008297:Male; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019785:Technetium Tc 99m Disofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019785:Technetium Tc 99m Disofenin