[Histological and clinical characteristics of cutaneous hemangiomas and vascular malformations].
One hundred and forty-two specimens of cutaneous vascular lesions were reviewed. All specimens were classified as hemangiomas (n = 114) or vascular malformations (n = 28) from this investigation. Hemangiomas in the proliferating phase (n = 55) were characterized by endothelial hyperplasia and in the regressive phase (n = 59) by fibrinoid degeneration and fat infiltration. The average number of mast cells was 25.73 +/- 9.82 in the proliferative phase and 5.12 +/- 3.24 in the regressive phase. Vascular malformations were characterized by normal endothelial turnover and a normal mast cell count (4.15 +/- 1.45). Clinically, hemangiomas exhibited a history of rapid neonatal growth and slow involution. Vascular malformations grew in proportion to the child and failed to regress.
Jin
B R
BR
Children's Hospital, Shanghai Medical University.
D000293:Adolescent; D001808:Blood Vessels / Q000002:abnormalities* / Q000473:pathology*; D002675:Child, Preschool; D005260:Female; D006391:Hemangioma / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies