title: Modulation of non-specific immunity by hippocampal stimulation.
abstract: Rats subjected to electrical stimulation of hippocampus (30 min/day for 4 days) showed an increase in the neutrophils in the peripheral blood when compared to sham (P < 0.01) and controls (P < 0.001). They also showed a significant decrease in lymphocytes, when compared to control rats (P < 0.001). Both sham and stimulated animals showed a significant decrease in total white blood cell count when compared to controls (P < 0.001). The phagocytic index of stimulated animals showed a significant increase from control (P < 0.001) and sham (P < 0.001). In addition, the stimulated animals showed a significant (P < 0.001) decrease in plasma corticosterone level when compared to sham and controls.
authors.affiliation: Department of Physiology, Dr. A.L.M.P.G. Institute of Basic Medical Sciences, University of Madras, Taramani, India.
authors.forename: R S
authors.initials: RS
authors.lastname: Devi
authors.forename: A
authors.initials: A
authors.lastname: Namasivayam
authors.forename: K
authors.initials: K
authors.lastname: Prabhakaran
mesh_terms: D000818:Animals; D001772:Blood Cell Count; D004558:Electric Stimulation; D006624:Hippocampus / Q000276:immunology / Q000502:physiology*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology; D008297:Male; D009504:Neutrophils / Q000166:cytology / Q000276:immunology; D010587:Phagocytosis; D051381:Rats; D017208:Rats, Wistar