title: Effects of preparation methods of biomedical samples on PIXE measurement sensitivity.
abstract: Instrumental sample preparation techniques for PIXE measurements of human blood serum and bovine muscle were investigated. The techniques studied were direct measurement of a drop, drying on a foil and on an Al cup, lyophilization on a foil, pellet pressing of dried material, microtome sectioning and biopsy preparation. The same serum and muscle were used in each procedure allowing the comparison of detection limits between different methods. The most beneficial technique for both samples was lyophilization and pellet pressing.
authors.affiliation: University of Helsinki, Department of Physics, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Kupila-Rantala
authors.forename: M
authors.initials: M
authors.lastname: Hyvönen-Dabek
authors.forename: J
authors.initials: J
authors.lastname: Räisänen
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis / Q000295:instrumentation*; D002417:Cattle; D006801:Humans; D009132:Muscles / Q000737:chemistry*; D013052:Spectrometry, X-Ray Emission / Q000379:methods*