title: [Fibrin agglutination of thyroid gland cysts after fine needle puncture].
abstract: Tolerance to and efficacy of a fibrin adhesive injected into thyroid cysts after their evacuation by fine needle puncture was investigated in 60 consecutive patients (52 women, 8 men; mean age 50 [18-82] years) with solitary thyroid cysts. The patients were randomly separated into two groups of 30 each. In group A patients the cysts were completely emptied by fine needle puncture under ultrasound control. In group B patients a fibrin adhesive (0.8-1.4 ml) was subsequently injected. 25 of 30 patients in group A had recurring cysts, twelve of which were larger than the original one. There were 13 recurrences in group B (P < 0.005), but only one was of a larger volume. In each group three patients reported a brief period of pain after the evacuation procedure. The described technique has proven to be reliable and well tolerated. Cysts obliterated by fibrin adhesive recurred less frequently and had a smaller volume than those only evacuated by needle puncture.
authors.affiliation: Abteilung Nuklearmedizin, Universität Göttingen.
authors.forename: D
authors.initials: D
authors.lastname: Sandrock
authors.forename: M
authors.initials: M
authors.lastname: Steinröder
authors.forename: D
authors.initials: D
authors.lastname: Emrich
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D003560:Cysts / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D001239:Inhalation; D007267:Injections; D008297:Male; D008875:Middle Aged; D009339:Needles; D011446:Prospective Studies; D012008:Recurrence; D013959:Thyroid Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D014463:Ultrasonography
chemical_list: D015718:Fibrin Tissue Adhesive