title: Effect of intermittent pneumatic leg compression on intracranial pressure in brain-injured patients.
abstract: OBJECTIVE
  To evaluate the effect of intermittent pneumatic leg compression on intracranial pressure and cerebral perfusion pressure in brain-injured patients.
  
  
  METHODS
  Prospective, sequential patient study.
  
  
  METHODS
  Surgical/trauma ICU of a community hospital providing regional trauma care.
  
  
  METHODS
  Twenty-four adult, brain-injured patients (mean Glasgow Coma Scale score = 6) who required hemodynamic and intracranial pressure monitoring.
  
  
  METHODS
  Placement of intermittent sequential pneumatic leg compression devices for prevention of venous thrombosis.
  
  
  METHODS
  Mean arterial pressure (MAP), heart rate, central venous pressure, and intracranial pressure were measured at baseline, and at 0, 10, 20, and 30 mins of intermittent pneumatic leg compression. Cerebral perfusion pressure was calculated as the difference between MAP and intracranial pressure.
  
  
  RESULTS
  No significant changes in MAP, central venous pressure, or intracranial pressure occurred during the study interval. Calculated cerebral perfusion pressure remained unchanged. A total of 23 of 24 study patients had intracranial pressure controlled by hyperventilation or pharmacologic measures within the normal range at the time of study.
  
  
  CONCLUSIONS
  Intermittent pneumatic leg compression results in no significant changes in intracranial pressure or cerebral perfusion pressure in stable, brain-injured patients who have intracranial pressure controlled by medical means.
authors.affiliation: University of California San Diego Medical Center.
authors.forename: J E
authors.initials: JE
authors.lastname: Davidson
authors.forename: D C
authors.initials: DC
authors.lastname: Willms
authors.forename: M S
authors.initials: MS
authors.lastname: Hoffman
mesh_terms: D001794:Blood Pressure; D001930:Brain Injuries / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D015600:Glasgow Coma Scale; D005676:Gravity Suits; D006801:Humans; D007427:Intracranial Pressure; D007866:Leg; D008297:Male; D011446:Prospective Studies; D013924:Thrombophlebitis / Q000517:prevention & control; D014193:Trauma Centers