title: Eyelid involvement in acanthosis nigricans.
abstract: We treated a 56-year-old man who had acanthosis nigricans associated with gastric adenocarcinoma and involving the axillae, hands, feet, anus, soft palate, and eyes. The patient developed epiphora from occlusion of the canaliculi with papillomatous lesions. Recognition of the ocular signs of this paraneoplastic syndrome may indicate to the ophthalmologist that the patient should have a thorough oncologic examination.
authors.affiliation: Department of Ophthalmology, University of California, Davis 95618.
authors.forename: E B
authors.initials: EB
authors.lastname: Groos
authors.forename: M J
authors.initials: MJ
authors.lastname: Mannis
authors.forename: T B
authors.initials: TB
authors.lastname: Brumley
authors.forename: A C
authors.initials: AC
authors.lastname: Huntley
mesh_terms: D000052:Acanthosis Nigricans / Q000150:complications / Q000473:pathology*; D000230:Adenocarcinoma / Q000150:complications; D005143:Eyelids / Q000473:pathology*; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000209:etiology; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000150:complications