title: Eczematous skin reaction from patch testing with aeroallergens in atopic children with and without atopic dermatitis.
abstract: To determine whether aeroallergens could induce eczematous lesions, 30 patients with atopic dermatitis were studied in comparison with 30 patients with respiratory atopy without atopic dermatitis. All patients were between 2 and 14 years of age. Patch testing with five aeroallergens--housedust, mite, cockroach, mold mix, and grass mix--was done on skin that was stripped by 10 applications of adhesive tape. Intradermal tests with the same antigens were done on the forearm. In 27 (90%) children with atopic dermatitis, patch testing with aeroallergens induced eczematous lesions at one or more sites. Mite, cockroach, house dust, mold mix, and grass mix caused reactions in 21 (70%), 21 (70%), 19 (63%), 15 (50%), and 13 (43%) patients, respectively. Three patients had a dermatitis flare at the antecubital and popliteal fossae during testing. Only three (10%) atopic children without atopic dermatitis had eczematous lesions, which was significantly different from children with atopic dermatitis (P < 10(-6)). Intradermal skin tests in both groups were not significantly different. This study supports previous reports that aeroallergens plays an important role in causing eczematous skin lesions.
authors.affiliation: Department of Pediatrics, Chulalongkorn University, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Wananukul
authors.forename: P
authors.initials: P
authors.lastname: Huiprasert
authors.forename: P
authors.initials: P
authors.lastname: Pongprasit
mesh_terms: D000293:Adolescent; D000485:Allergens; D000818:Animals; D000946:Antigens, Fungal / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003058:Cockroaches / Q000276:immunology; D003876:Dermatitis, Atopic / Q000276:immunology*; D004391:Dust; D004485:Eczema / Q000209:etiology*; D006801:Humans; D007428:Intradermal Tests; D008925:Mites / Q000276:immunology; D010328:Patch Tests; D006109:Poaceae; D012130:Respiratory Hypersensitivity / Q000276:immunology*
chemical_list: D000485:Allergens; D000946:Antigens, Fungal; D004391:Dust