Molecular analysis of the microtubule motor dynein.
Dynein is a large enzyme complex that has been found in recent years to be responsible for a variety of forms of intracellular movement associated with microtubules. Molecular analysis of several of the polypeptide components of dynein and a related complex has provided important new insight into their structural organization and mechanism of action in the cell.
Vallee
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Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545.
D000818:Animals; D004398:Dyneins / Q000737:chemistry* / Q000378:metabolism*; D046911:Macromolecular Substances; D008870:Microtubules / Q000201:enzymology*; D008961:Models, Structural; D011487:Protein Conformation; D017510:Protein Folding
D046911:Macromolecular Substances; D004398:Dyneins