Chronic pancreatitis: MR imaging features before and after administration of gadopentetate dimeglumine.
Magnetic resonance (MR) imaging was performed in patients with a history (> 1 year) of inflammatory pancreatic disease. Calcification was seen at recent computed tomographic examinations in 13 patients and was not seen in nine patients. On fat-suppressed spin-echo images, the signal-to-noise ratio of the pancreas was significantly lower (P < .001) in patients with pancreatic calcification (18.2 +/- 2.5 vs 38.1 +/- 6.1). On fast low-angle shot images, the percentage of contrast enhancement was also significantly lower (P < .001) in patients with calcification (26.1% +/- 5.8 vs 78.7% +/- 15.9). The results suggest that MR imaging may be useful in evaluating patients with a long history of pancreatic disease for the presence of irreversible disease.
Semelka
R C
RC
Department of Radiology, St Boniface General Hospital MRI Facility, Winnipeg, Manitoba, Canada.
Shoenut
J P
JP
Kroeker
M A
MA
Micflikier
A B
AB
D002114:Calcinosis / Q000175:diagnosis; D002908:Chronic Disease; D003287:Contrast Media; D004338:Drug Combinations; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008536:Meglumine; D008875:Middle Aged; D009942:Organometallic Compounds; D010179:Pancreas / Q000473:pathology*; D010195:Pancreatitis / Q000175:diagnosis*; D004369:Pentetic Acid
D003287:Contrast Media; D004338:Drug Combinations; D009942:Organometallic Compounds; D008536:Meglumine; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA