Direct chromosome analysis of 50 primary breast carcinomas.
Direct chromosome analyses were performed in 50 cases of primary breast carcinoma. Thirty-six cases had modal chromosome counts in the diploid range; the other 14 cases were polyploid. Of the 22 cases with detailed G-banding analyses, the most frequent structural changes involved chromosome 1 (15 of 22), 3 (13 of 22), and 6 (13 of 22). Deletion of chromosome 1p was noted in nine cases, and both 3p- and 6q- were noted in 10 cases.
Lu
Y J
YJ
Department of Biology, Harbin Medical College, People's Republic of China.
Xiao
S
S
Yan
Y S
YS
Fu
S B
SB
Liu
Q Z
QZ
Li
P
P
D001943:Breast Neoplasms / Q000235:genetics*; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002893:Chromosomes, Human, Pair 3; D002896:Chromosomes, Human, Pair 6; D005260:Female; D006801:Humans; D007621:Karyotyping