[The relative role of different mechanisms of glucose absorption in the small intestine under physiological conditions].
Chronic experiments in animals have shown that, even at the maximal glucose (75 mM) and maltose (37.5 mM) concentrations in the initial perfusate, the rate of glucose transfer by a solvent drug does not exceed 10 and 13 per cent, resp. of the total rate of glucose absorption in an isolated intestinal loop. The absorption of glucose under physiological conditions seems to be due mainly to its active transport across the apical membrane of the enterocytes.
Gromova
L V
LV
Gruzdkov
A A
AA
D000818:Animals; D001693:Biological Transport, Active / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D005947:Glucose / Q000378:metabolism*; D006868:Hydrolysis; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000502:physiology*; D007421:Intestine, Small / Q000502:physiology*; D008297:Male; D008320:Maltose / Q000378:metabolism; D010477:Perfusion / Q000379:methods; D051381:Rats; D017208:Rats, Wistar; D014867:Water / Q000378:metabolism
D014867:Water; D008320:Maltose; D005947:Glucose