title: [Clinical, electrocardiographic and electrophysiologic evaluation of intravenous and oral ipratropium bromide in patients with symptomatic bradycardia].
abstract: Both oral and intravenous ipratropium bromide were assessed clinically, electrocardiographically and electrophysiologically in 15 patients with symptomatic bradycardia, aged between 32 and 79 years. Ipratropium bromide administered intravenously accelerated heart rate by more than 30% in the majority of patients. Electrophysiologically it normalized conduction time and sinus node response. Electrophysiological studies did not enable to foreseen the efficiency of oral form which may be useful in the treatment of symptomatic bradycardia in increased parasympathetic tone and both mild, and moderate sinus node insufficiency.
authors.affiliation: Oddziału Internistyczno-Kardiologicznego Wojewódzkiego Szpitala Specjalistycznego, Wrocławiu.
authors.forename: J
authors.initials: J
authors.lastname: Lewczuk
authors.forename: P
authors.initials: P
authors.lastname: Palka
authors.forename: K
authors.initials: K
authors.lastname: Reczuch
authors.forename: P
authors.initials: P
authors.lastname: Piszko
authors.forename: J
authors.initials: J
authors.lastname: Spikowski
authors.forename: K
authors.initials: K
authors.lastname: Wrabec
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D001919:Bradycardia / Q000175:diagnosis / Q000188:drug therapy*; D004562:Electrocardiography; D004594:Electrophysiology; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D009241:Ipratropium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D009241:Ipratropium