Keto/enol epoxy steroids: a new structural class of HIV-1 Tat inhibitors.
Michne
W F
WF
Department of Medicinal Chemistry, Sterling Winthrop Pharmaceuticals Research Division, Malvern, Pennsylvania 19355.
Schroeder
J D
JD
Bailey
T R
TR
Young
D C
DC
Hughes
J V
JV
Dutko
F J
FJ
D000732:Androstanols / Q000737:chemistry / Q000494:pharmacology*; D000734:Androstenediols / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D015696:Gene Products, tat / Q000037:antagonists & inhibitors*; D015756:Genes, tat; D015497:HIV-1 / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014162:Transfection; D054322:tat Gene Products, Human Immunodeficiency Virus
D000732:Androstanols; D000734:Androstenediols; D015696:Gene Products, tat; D054322:tat Gene Products, Human Immunodeficiency Virus; C083424:2-carbamoyl-4,5-epoxyandrost-2-ene-3,17-diol; C083425:4,5-epoxy-17-hydroxy-2-methylsulfonyl-3-androstanone