Distribution of the HLA-DQ alpha alleles and genotypes in a sample of a population from Barcelona (Spain).
Allele and genotype frequencies at the HLA-DQ alpha locus were determined by the use of polymerase chain reaction (PCR) and the reverse dot blot format. 6 HLA-DQ alpha alleles and 21 genotypes were detected among the 178 unrelated individuals from Barcelona. A fair agreement was found between observed and expected numbers assuming a Hardy-Weinberg equilibrium. The Barcelona population is statistically similar to the Finnish population, but differs significantly from the Japanese, Black and Caucasoid series.
Huguet
E
E
Laboratorio de Hemogenética Forense, Facultad de Medicina, Universidad de Barcelona, Spain.
Gené
M
M
Corbella
J
J
Moreno
P
P
D000483:Alleles; D005787:Gene Frequency; D005838:Genotype; D006683:HLA-DQ Antigens / Q000235:genetics*; D006801:Humans; D011110:Polymorphism, Genetic; D013030:Spain / Q000453:epidemiology
D006683:HLA-DQ Antigens