title: The role of surgical therapy in patients with nonmetastatic Ewing's sarcoma of the limbs.
abstract: Of 131 patients with primary Ewing's sarcoma (ES) with extremity locations, treated between April 1972 and May 1987, 13 had amputation; 56 had a local resection with 31 (55%) requiring radiation therapy (RT) as an adjuvant to local therapy. Sixty-two of 131 patients (47%) had RT only. Local recurrences were reported in 5% of patients treated with surgery alone, 1% of the group treated with surgery and radiation therapy, 24% of patients treated with radiation therapy alone (46% for cesium-radiation therapy, and 12% with cobalt-radiation therapy).
authors.affiliation: Clinica Ortopedica dell'Università, Istituto Rizzoli, Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Toni
authors.forename: J R
authors.initials: JR
authors.lastname: Neff
authors.forename: A
authors.initials: A
authors.lastname: Sudanese
authors.forename: D
authors.initials: D
authors.lastname: Ciaroni
authors.forename: G
authors.initials: G
authors.lastname: Bacci
authors.forename: P
authors.initials: P
authors.lastname: Picci
authors.forename: E
authors.initials: E
authors.lastname: Barbieri
authors.forename: M
authors.initials: M
authors.lastname: Campanacci
authors.forename: A
authors.initials: A
authors.lastname: Giunti
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D002588:Cesium Radioisotopes / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy / Q000009:adverse effects; D005121:Extremities; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009381:Neoplasms, Radiation-Induced; D011183:Postoperative Complications / Q000209:etiology; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D012509:Sarcoma / Q000209:etiology; D012512:Sarcoma, Ewing / Q000532:radiotherapy / Q000601:surgery*
chemical_list: D002588:Cesium Radioisotopes; D003037:Cobalt Radioisotopes