The human pancreatic lipase-encoding gene: structure and conservation of an Alu sequence in the lipase gene family.
The isolation and characterization of the human gene (hPL) encoding pancreatic lipase is reported. The gene has 13 exons dispersed in about 20 kb of genomic DNA. A pseudogene of hPL was also partially characterized. An Alu sequence is conserved in the homologous introns of hPL and the lipoprotein lipase-encoding gene.
Sims
H F
HF
Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110.
Jennens
M L
ML
Lowe
M E
ME
D001483:Base Sequence; D017124:Conserved Sequence; D005091:Exons; D006801:Humans; D007438:Introns; D008049:Lipase / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family; D010179:Pancreas / Q000201:enzymology*; D011487:Protein Conformation; D011544:Pseudogenes; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
D008049:Lipase