title: Localization of indoleamine 2,3-dioxygenase gene (INDO) to chromosome 8p12-->p11 by fluorescent in situ hybridization.
abstract: Indolamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase are two enzymes that degrade tryptophan to N-formylkynurenine. The gene (TDO2) for tryptophane 2,3-dioxygenase has been localized to 4q31-->32. We now report localization of INDO (the gene encoding indolamine 2,3-dioxygenase) by fluorescent in situ hybridization to 8p12-->p11.
authors.affiliation: Tumor Cytogenetics Laboratory, Mount Sinai Medical Center, New York, NY 10029.
authors.forename: V
authors.initials: V
authors.lastname: Najfeld
authors.forename: J
authors.initials: J
authors.lastname: Menninger
authors.forename: D
authors.initials: D
authors.lastname: Muhleman
authors.forename: D E
authors.initials: DE
authors.lastname: Comings
authors.forename: S L
authors.initials: SL
authors.lastname: Gupta
mesh_terms: D002898:Chromosomes, Human, Pair 8; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D014366:Tryptophan Oxygenase / Q000235:genetics*
chemical_list: D014366:Tryptophan Oxygenase