pH mapping in living tissues: an application of in vivo 31P NMR chemical shift imaging.
Chemical shifts were extracted from in vivo 3-dimensional 31P NMR CSI data and pH images were constructed. The images could spatially resolve tissue pH ranging from 5.8 to 7.2 (with uncertainty of 0.11-0.17 pH unit) in an ischemia-reperfusion model of diabetic rat calf muscles.
Morikawa
S
S
Molecular Neurobiology Research Center, Shiga University of Medical Science, Japan.
Inubushi
T
T
Kito
K
K
Kido
C
C
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000473:pathology; D006863:Hydrogen-Ion Concentration; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008961:Models, Structural; D009132:Muscles / Q000473:pathology*; D010758:Phosphorus / Q000378:metabolism; D051381:Rats; D015427:Reperfusion Injury / Q000175:diagnosis*
D010758:Phosphorus