title: [Nedocromil in treating chronic bronchial asthma of a moderate course].
abstract: Randomized, double blind, placebo controlled clinical studies aimed at evaluating the efficiency of nedocromil sodium (Tilade) in the form of metered dosimeter aerosol. Studies involved patients with moderate chronic bronchial asthma controlled with beta 2-agonists and theophylline in the form of sustained release preparations. Forty patients completed the studies. All patients were examined clinically (staging of the symptoms and doses of drugs) and spirometrically prior to and after 4 and 8 weeks of the treatment with nedocromil sodium. Statistically significant clinical improvement and spirometric improvement as well in patients treated with nedocromil sodium were noted. It may be concluded that nedocromil sodium is effective and well tolerated adjuvant therapy in the bronchial asthma.
authors.affiliation: Katedry i Kliniki Chorób Wewnetrznych i Alergologii Sl. AM.
authors.forename: B
authors.initials: B
authors.lastname: Rogala
authors.forename: J
authors.initials: J
authors.lastname: Jarzab
authors.forename: E
authors.initials: E
authors.lastname: Rogala
authors.forename: M
authors.initials: M
authors.lastname: Nowakowski
mesh_terms: D000280:Administration, Inhalation; D000818:Animals; D001249:Asthma / Q000188:drug therapy*; D002415:Cats; D002908:Chronic Disease; D004311:Double-Blind Method; D006801:Humans; D008875:Middle Aged; D017835:Nedocromil / Q000008:administration & dosage / Q000627:therapeutic use*; D013147:Spirometry; D016896:Treatment Outcome
chemical_list: D017835:Nedocromil