title: Intraocular lymphoma invades the optic nerve and orbit.
abstract: A diagnosis uveitis OS was made in a 54-year-old woman; this was resistant to corticosteroid treatment. One year later, both eyes were involved. Examination of the vitreous aspirate and the results of a chorioretinal biopsy OD did not yield a correct diagnosis. Computed tomographic scanning showed orbital invasion OD. Malignant lymphoma was diagnosed after a biopsy specimen of the orbital contents was studied histopathologically. Radiotherapy and chemotherapy diminished the orbital mass and intraocular lesions. After regression of the orbital lesion, a brain tumor was found and treated with radiotherapy and chemotherapy. At age 57 years, the patient died. We believe that our patient had a rare case of intraocular lymphoma associated with orbital invasion.
authors.affiliation: Department of Ophthalmology, Shimane Medical University, Izumo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Noda
authors.forename: S
authors.initials: S
authors.lastname: Hayasaka
authors.forename: T
authors.initials: T
authors.lastname: Setogawa
mesh_terms: D003390:Cranial Nerve Neoplasms / Q000473:pathology*; D005134:Eye Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000473:pathology*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009901:Optic Nerve Diseases / Q000473:pathology*; D009918:Orbital Neoplasms / Q000473:pathology*