Spinal cord compression in metastatic cervical cancer.
Spinal cord compression secondary to metastatic cervical cancer may not be considered as a possible cause of neurologic symptoms by primary care physicians who do not often treat these patients. Delays in diagnosis and treatment may result in irreversible but potentially preventable neurologic changes. This report describes 5 cases of spinal cord compression in patients with metastatic cervical carcinoma, 2 of whom were previously undiagnosed with cervical cancer. These 2 patients represent 1.6% (2 of 121) of all new cervical cancer cases diagnosed during this time period. Two of 5 patients (40%) with spinal cord compression showed improvement following therapy by regaining the ability to walk, while none of the remaining patients had further acute deterioration of neurologic function. The mean survival of patients presenting with spinal cord compression from cervical cancer in this series was 4 months (maximum 6 months). This series illustrates the relative frequency with which spinal cord compression is seen in patients with a new diagnosis of invasive cancer. This diagnosis should be considered when evaluating neurologic complaints in known cervical cancer patients or any woman with apparent pelvic pathology. Rapid diagnosis and treatment of these lesions, while not likely to improve overall survival significantly, can improve function and alleviate symptoms.
Robinson
W R
WR
Department of Obstetrics/Gynecology, LAC/USC Medical Center 90033.
Muderspach
L I
LI
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000532:radiotherapy / Q000556:secondary; D005260:Female; D006801:Humans; D008875:Middle Aged; D011879:Radiotherapy Dosage; D013117:Spinal Cord Compression / Q000209:etiology* / Q000532:radiotherapy; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000532:radiotherapy