title: The effect of fish oil supplements on blood pressure.
abstract: We conducted a double-blind, placebo-controlled crossover study to determine the effects of fish oil supplementation on blood pressure in middle-aged men. Subjects were randomly assigned to consume either 20 g of fish oil or safflower oil for 12 weeks and then consume the other oil for an additional 12 weeks after a 4-week washout period. We found no significant changes from the pretreatment value in systolic or diastolic blood pressure with the use of fish oil supplements. In addition, there were no significant differences in the posttreatment blood pressures comparing the fish and safflower oil phases of the study.
authors.affiliation: Department of Medicine, University of Minnesota, Minneapolis.
authors.forename: R P
authors.initials: RP
authors.lastname: Lofgren
authors.forename: T J
authors.initials: TJ
authors.lastname: Wilt
authors.forename: K L
authors.initials: KL
authors.lastname: Nichol
authors.forename: L
authors.initials: L
authors.lastname: Crespin
authors.forename: R
authors.initials: R
authors.lastname: Pluhar
authors.forename: J
authors.initials: J
authors.lastname: Eckfeldt
mesh_terms: D001794:Blood Pressure / Q000187:drug effects*; D004311:Double-Blind Method; D005395:Fish Oils / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012450:Safflower Oil / Q000494:pharmacology / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D005395:Fish Oils; D012450:Safflower Oil