Amino acid sequences of mammalian kazal-type proteinase inhibitors from salivary glands.
1. The amino acid sequences of bikazins (the double-headed Kazal-type proteinase inhibitors from submandibular glands) isolated from the snow leopard (Unica unica), the European mink (Mustela lutreola), and the European pine marten (Martes martes) were determined. 2. N-terminal domains of bikazins are characterized by a cysteine residue spacing that differs from that of C-terminal domains of bikazins and other Kazal-type proteinase inhibitor domains. 3. N-terminal sequences of bikazins seem to be specific for, and highly conserved within, each Carnivora family.
Hochstrasser
K
K
Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Universität München, Germany.
Wachter
E
E
Reisinger
P W
PW
Greim
M
M
Albrecht
G J
GJ
Gebhard
W
W
D000595:Amino Acid Sequence; D000818:Animals; D002335:Carnivora; D003545:Cysteine / Q000737:chemistry; D006031:Glycosylation; D008907:Mink; D008969:Molecular Sequence Data; D011480:Protease Inhibitors / Q000737:chemistry*; D012471:Salivary Proteins and Peptides / Q000737:chemistry*; D013045:Species Specificity; D013363:Submandibular Gland / Q000737:chemistry*; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000737:chemistry
D011480:Protease Inhibitors; D012471:Salivary Proteins and Peptides; C083355:bikazin; D014359:Trypsin Inhibitor, Kazal Pancreatic; D003545:Cysteine