title: Antibiotic susceptibility, serovars and auxotypes of gonococcal isolates in Stockholm. Relation to geographical origin of the infection.
abstract: The antibiotic susceptibility, serovars and auxotypes were investigated in gonococcal strains isolated from all patients with gonorrhoea during one year in Stockholm, Sweden. The results were correlated to geographical origin of the infection. A total of 394 gonococcal strains were isolated from 392 patients, 135 (34%) women and 257 (66%) men. Beta-lactamase-producing gonococcal strains (PPNG) were isolated from 5% of the women and 16% of the men. Men had acquired their infection abroad more often than women (54% vs 33%) (P < 0.001). The majority (81%) of the PPNG infections were imported. Some serovars and auxotypes were more common among imported strains than among indigenous ones. All strains were sensitive to spectinomycin and 2 strains had decreased susceptibility to norfloxacin and ciprofloxacin. Decreased susceptibility to benzylpenicillin, ampicillin, doxycycline and cefuroxime was related to the geographical origin of the strains with strains imported from regions other than Europe being the most resistant.
authors.affiliation: Department of Clinical Bacteriology, Huddinge Hospital, Stockholm, Sweden.
authors.forename: S M
authors.initials: SM
authors.lastname: Bygdeman
authors.forename: A K
authors.initials: AK
authors.lastname: Rudén
authors.forename: A
authors.initials: A
authors.lastname: Jonsson
authors.forename: P
authors.initials: P
authors.lastname: Lidbrink
authors.forename: M B
authors.initials: MB
authors.lastname: Olofsson
authors.forename: M
authors.initials: M
authors.lastname: Bäckman
authors.forename: B
authors.initials: B
authors.lastname: Gästrin
authors.forename: I
authors.initials: I
authors.lastname: Kallings
authors.forename: M
authors.initials: M
authors.lastname: Ramberg
authors.forename: M
authors.initials: M
authors.lastname: Rylander
mesh_terms: D000293:Adolescent; D000328:Adult; D000349:Africa; D000667:Ampicillin / Q000494:pharmacology / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001208:Asia; D002444:Cefuroxime / Q000494:pharmacology / Q000627:therapeutic use; D004318:Doxycycline / Q000494:pharmacology / Q000627:therapeutic use; D005060:Europe; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000302:isolation & purification; D010400:Penicillin G / Q000494:pharmacology / Q000627:therapeutic use; D012537:Scandinavian and Nordic Countries; D013020:South America; D013548:Sweden / Q000453:epidemiology; D014481:United States
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin; D004318:Doxycycline; D002444:Cefuroxime; D010400:Penicillin G