title: Effect of carnitine supplement to the dam on plasma carnitine concentration in the sucking foal.
abstract: The changes in carnitine in plasma and milk during the first 3 months of lactation were studied in 14 broodmares and their foals. Six of the mares (Group S) were given a supplement of 10 g carnitine split between the morning and evening feeds, starting 2 weeks before birth. At birth the plasma carnitine concentration in Group S mares was about twice that in Group NS mares (no supplement). In both groups the concentration initially declined in the days after birth. Whilst this trend was reversed in Group S mares, the concentration in Group NS mares remained at a reduced level for the remainder of the study. Milk concentrations declined continuously over the monitoring period in both groups. There was no apparent relationship between milk and plasma concentrations. Despite this the milk concentration tended to be higher in Group S than in Group NS mares although differences were not significant. There was an immediate drop in the plasma concentration in foals after birth which was reversed in foals of Group S mares but not in those of Group NS mares. There were no apparent side effects of carnitine supplementation.
authors.affiliation: Department of Physiology, Animal Health Trust, Newmarket, Suffolk, UK.
authors.forename: A E
authors.initials: AE
authors.lastname: Benamou
authors.forename: R C
authors.initials: RC
authors.lastname: Harris
mesh_terms: D000821:Animal Feed; D000818:Animals; D000833:Animals, Suckling / Q000097:blood* / Q000254:growth & development; D002331:Carnitine / Q000008:administration & dosage / Q000032:analysis / Q000097:blood*; D005260:Female; D005527:Food, Fortified; D006736:Horses / Q000097:blood* / Q000254:growth & development; D007774:Lactation / Q000097:blood*; D008892:Milk / Q000737:chemistry*
chemical_list: D002331:Carnitine