Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.
Olson
S T
ST
Division of Biochemical Research, Henry Ford Hospital, Detroit, Michigan 48202.
Björk
I
I
Shore
J D
JD
D000991:Antithrombins / Q000302:isolation & purification / Q000378:metabolism*; D001779:Blood Coagulation Factors / Q000037:antagonists & inhibitors*; D002846:Chromatography, Affinity / Q000379:methods; D002850:Chromatography, Gel / Q000379:methods; D002852:Chromatography, Ion Exchange / Q000379:methods; D010450:Endopeptidases / Q000097:blood*; D005341:Fibrinolysin / Q000037:antagonists & inhibitors; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D007610:Kallikreins / Q000037:antagonists & inhibitors; D007700:Kinetics; D008433:Mathematics; D011480:Protease Inhibitors / Q000494:pharmacology*; D013050:Spectrometry, Fluorescence / Q000379:methods; D013917:Thrombin / Q000037:antagonists & inhibitors / Q000378:metabolism; D014357:Trypsin / Q000378:metabolism
D000991:Antithrombins; D001779:Blood Coagulation Factors; D011480:Protease Inhibitors; D006493:Heparin; D010450:Endopeptidases; D007610:Kallikreins; D014357:Trypsin; D013917:Thrombin; D005341:Fibrinolysin