title: Argentine randomized trial of percutaneous transluminal coronary angioplasty versus coronary artery bypass surgery in multivessel disease (ERACI): in-hospital results and 1-year follow-up. ERACI Group.
abstract: OBJECTIVE
  This study was designed to compare freedom from combined cardiac events (death, angina, myocardial infarction) at 1-, 3- and 5-year follow-up in patients with multivessel disease randomized to either percutaneous transluminal coronary angioplasty or coronary artery bypass graft surgery.
  
  
  BACKGROUND
  Percutaneous transluminal coronary angioplasty has been an effective approach in patients with coronary artery disease, but its role in patients with multivessel coronary artery disease is still controversial.
  
  
  METHODS
  One-hundred twenty-seven patients with multivessel disease and lesions suitable for either form of therapy were randomized to either coronary artery bypass grafting (n = 64) or coronary angioplasty (n = 63). In this study we report the immediate results and freedom from combined cardiac events at 1-year follow-up.
  
  
  RESULTS
  Demographic, clinical and angiographic characteristics were similar in both groups. There were no differences in in-hospital deaths, frequency of periprocedure myocardial infarction or need for emergency revascularization procedures between the two groups. At 1-year follow-up, there were no differences in mortality or in the incidence of myocardial infarction between the groups. However, patients treated with coronary artery bypass grafting were more frequently free of angina, reinterventions and combined cardiac events than were patients treated with coronary angioplasty (83.5% vs. 63.7%, p < 0.005). In-hospital cost and cumulative cost at 1-year follow-up were greater for the coronary artery bypass grafting than for the coronary angioplasty group.
  
  
  CONCLUSIONS
  No significant differences were found in major in-hospital complications between patients treated with coronary artery bypass grafting or coronary angioplasty. Although at 1-year follow-up there were no differences in survival and freedom from myocardial infarction, patients in the coronary artery bypass grafting group were more frequently free from angina, reinterventions and combined events than were patients in the coronary angioplasty group.
authors.affiliation: Cardiac Unit, Anchorena Hospital, Buenos Aires, Argentina.
authors.forename: A
authors.initials: A
authors.lastname: Rodriguez
authors.forename: F
authors.initials: F
authors.lastname: Boullon
authors.forename: N
authors.initials: N
authors.lastname: Perez-Baliño
authors.forename: C
authors.initials: C
authors.lastname: Paviotti
authors.forename: M I
authors.initials: MI
authors.lastname: Liprandi
authors.forename: I F
authors.initials: IF
authors.lastname: Palacios
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary / Q000191:economics / Q000592:standards*; D001118:Argentina / Q000453:epidemiology; D002561:Cerebrovascular Disorders / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D001026:Coronary Artery Bypass / Q000191:economics / Q000592:standards*; D003327:Coronary Disease / Q000145:classification / Q000150:complications / Q000191:economics / Q000401:mortality / Q000628:therapy*; D004630:Emergencies; D005260:Female; D005500:Follow-Up Studies; D017048:Health Care Costs; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D012086:Reoperation; D012720:Severity of Illness Index; D015996:Survival Rate; D016896:Treatment Outcome