Adverse drug reaction to metoclopramide hydrochloride in a macaw with proventricular dilatation syndrome.
A 4-year-old female blue and gold macaw (Ara ararauna) with a history of chronic vomiting was treated with metoclopramide hydrochloride. After the second treatment, ataxia, torticollis, and opisthotonos became evident. These signs resolved with the administration of diphenhydramine hydrochloride. Despite supportive care, the bird died several days later. Histologic lesions were suggestive of proventricular dilatation syndrome.
Massey
J G
JG
CARE Animal Hospital, Inc., Honolulu, HI 96816.
D000818:Animals; D001715:Bird Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000209:etiology; D004108:Dilatation, Pathologic / Q000150:complications / Q000662:veterinary; D004155:Diphenhydramine / Q000627:therapeutic use; D005260:Female; D008787:Metoclopramide / Q000009:adverse effects* / Q000627:therapeutic use; D009422:Nervous System Diseases / Q000139:chemically induced / Q000188:drug therapy / Q000662:veterinary*; D011531:Proventriculus; D011563:Psittaciformes; D013272:Stomach Diseases / Q000150:complications / Q000662:veterinary*; D013577:Syndrome; D014839:Vomiting / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary
D004155:Diphenhydramine; D008787:Metoclopramide