title: An inexpensive infrared growth sensor array for detection of bacterial antibiotic susceptibility.
abstract: An inexpensive infrared sensor was constructed and used for the rapid testing of bacterial antibiotic susceptibility by detection of changes in absorbance at 950 nm. By comparing cultures of clinical isolates together with control strains (Escherichia coli NCTC 10418, Staphylococcus aureus NCTC 6571 or Pseudomonas aeruginosa NCTC 10662) after addition of an antibiotic, results on susceptibility were obtained within 3-5 h from the original plate culture. Representative strains of E. coli, P. aeruginosa, and S. aureus were tested successfully against ampicillin, penicillin, gentamicin or ciprofloxacin.
authors.affiliation: School of Pure and Applied Biology, University of Wales College of Cardiff, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Mason
authors.forename: A L
authors.initials: AL
authors.lastname: Lloyd
authors.forename: D
authors.initials: D
authors.lastname: Lloyd
mesh_terms: D000667:Ampicillin / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D002939:Ciprofloxacin / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D005069:Evaluation Studies as Topic; D005839:Gentamicins / Q000494:pharmacology; D006801:Humans; D007259:Infrared Rays; D008826:Microbial Sensitivity Tests / Q000295:instrumentation*; D010406:Penicillins / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D005839:Gentamicins; D010406:Penicillins; D002939:Ciprofloxacin; D000667:Ampicillin