Unusual findings in a myeloma kidney: a light- and electron-microscopic study.
A case of IgD myeloma together with the existence of myelofibrosis is presented. More interesting is the concurrent presence of cast nephropathy, light chain deposition and amyloidosis in the kidney. Peculiar light-microscopic, immunohistochemical, immunofluorescence and ultrastructural findings were also noted. The possible mechanisms and implications for such findings were discussed. This case was analyzed together with a review of local pictures of renal involvement in multiple myeloma.
Lam
K Y
KY
Department of Pathology, University of Hong Kong.
Chan
K W
KW
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000686:Amyloidosis / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans; D007072:Immunoglobulin D; D007146:Immunoglobulin lambda-Chains; D007668:Kidney / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000276:immunology / Q000473:pathology*; D055728:Primary Myelofibrosis / Q000150:complications
D007072:Immunoglobulin D; D007146:Immunoglobulin lambda-Chains