title: Is skewed X inactivation responsible for symptoms in female carriers for adrenoleucodystrophy?
abstract: A study of X inactivation in 12 female carriers for adrenoleucodystrophy showed no evidence that skewed patterns are related to clinical manifestation. Other possible mechanisms to explain manifestation in females are considered.
authors.affiliation: Sub-Department of Clinical Genetics, University of Birmingham, Birmingham Maternity Hospital, Edgbaston, UK.
authors.forename: E
authors.initials: E
authors.lastname: Watkiss
authors.forename: T
authors.initials: T
authors.lastname: Webb
authors.forename: S
authors.initials: S
authors.lastname: Bundey
mesh_terms: D000293:Adolescent; D000326:Adrenoleukodystrophy / Q000235:genetics*; D000328:Adult; D000368:Aged; D004303:Dosage Compensation, Genetic; D005260:Female; D006579:Heterozygote; D006801:Humans; D008875:Middle Aged