title: Direct chromosome analysis of 50 primary breast carcinomas.
abstract: Direct chromosome analyses were performed in 50 cases of primary breast carcinoma. Thirty-six cases had modal chromosome counts in the diploid range; the other 14 cases were polyploid. Of the 22 cases with detailed G-banding analyses, the most frequent structural changes involved chromosome 1 (15 of 22), 3 (13 of 22), and 6 (13 of 22). Deletion of chromosome 1p was noted in nine cases, and both 3p- and 6q- were noted in 10 cases.
authors.affiliation: Department of Biology, Harbin Medical College, People's Republic of China.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Lu
authors.forename: S
authors.initials: S
authors.lastname: Xiao
authors.forename: Y S
authors.initials: YS
authors.lastname: Yan
authors.forename: S B
authors.initials: SB
authors.lastname: Fu
authors.forename: Q Z
authors.initials: QZ
authors.lastname: Liu
authors.forename: P
authors.initials: P
authors.lastname: Li
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics*; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002893:Chromosomes, Human, Pair 3; D002896:Chromosomes, Human, Pair 6; D005260:Female; D006801:Humans; D007621:Karyotyping