title: Lithium induces changes in the plasma membrane protein pattern of early amphibian embryos.
abstract: The plasma membrane protein pattern of Rana ridibunda embryos subjected to lithium (Li) treatment at various stages of development was examined by two-dimensional gel electrophoresis. Differences were observed at the neurula stage not only as compared to controls but among lithium-treated embryos as well. Of particular interest was the presence of proteins, specific for the gastrula stage, in lithium-treated embryos. The results are discussed in relation to the well-known effect of lithium on amphibian morphogenesis.
authors.affiliation: Department of Zoology, School of Sciences, University of Thessaloniki, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Lazou
authors.forename: A
authors.initials: A
authors.lastname: Beis
mesh_terms: D000818:Animals; D002970:Cleavage Stage, Ovum / Q000187:drug effects; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D008094:Lithium / Q000633:toxicity*; D008565:Membrane Proteins / Q000187:drug effects*; D009436:Neural Tube Defects / Q000139:chemically induced*; D011895:Rana ridibunda
chemical_list: D008565:Membrane Proteins; D008094:Lithium