title: Pharmacological bridge to cardiac transplantation: current limitations.
abstract: Addition of intravenous enoximone to sympathomimetic agents permits a rapid and drastic improvement in the clinical and hemodynamical condition of patients in cardiogenic shock referred for a mechanical bridge to transplantation. The present experience, based on the management of 52 patients, permits us to point out the current limitations of this pharmacological bridge: the rate of sudden death, the incompleteness of the physical rehabilitation of the patients, and the vanishing effect of intravenous enoximone.
authors.affiliation: Centre de Recherches Chirurgicales, CHU Henri Mondor, Faculté de Médicine, Creteil, France.
authors.forename: D Y
authors.initials: DY
authors.lastname: Loisance
authors.forename: P H
authors.initials: PH
authors.lastname: Deleuze
authors.forename: R
authors.initials: R
authors.lastname: Houel
authors.forename: C
authors.initials: C
authors.lastname: Benvenuti
authors.forename: A
authors.initials: A
authors.lastname: el Sayed
authors.forename: J P
authors.initials: JP
authors.lastname: Mazzucotelli
authors.forename: A
authors.initials: A
authors.lastname: Tarral
authors.forename: J P
authors.initials: JP
authors.lastname: Saal
authors.forename: J P
authors.initials: JP
authors.lastname: Cachera
mesh_terms: D000328:Adult; D001243:Assisted Circulation; D002315:Cardiopulmonary Bypass; D002423:Cause of Death; D004334:Drug Administration Schedule; D017335:Enoximone / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology; D016027:Heart Transplantation / Q000502:physiology*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D012151:Resuscitation
chemical_list: D017335:Enoximone