title: The cytoplasmic domain of the human T-cell leukemia virus type I envelope can modulate envelope functions in a cell type-dependent manner.
abstract: C-terminal truncations of the human T-cell leukemia virus type I envelope affected the intracellular maturation and syncytium formation in a cell type-dependent manner. The intracytoplasmic domain appears dispensable for syncytium formation, but its truncation can modulate the envelope functionality in some cell types.
authors.affiliation: Centre National de la Recherche Scientifique UA 1156, Institut Gustave Roussy, Villejuif, France.
authors.forename: C
authors.initials: C
authors.lastname: Pique
authors.forename: D
authors.initials: D
authors.lastname: Pham
authors.forename: T
authors.initials: T
authors.lastname: Tursz
authors.forename: M C
authors.initials: MC
authors.lastname: Dokhélar
mesh_terms: D002460:Cell Line / Q000382:microbiology; D004252:DNA Mutational Analysis; D015686:Gene Products, env / Q000235:genetics*; D014644:Genetic Variation; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D011487:Protein Conformation; D015682:Retroviridae Proteins, Oncogenic / Q000235:genetics*; D014162:Transfection; D014759:Viral Envelope Proteins / Q000235:genetics*; D014760:Viral Fusion Proteins / Q000235:genetics*
chemical_list: D015686:Gene Products, env; D015682:Retroviridae Proteins, Oncogenic; D014759:Viral Envelope Proteins; D014760:Viral Fusion Proteins; C055266:gp46 protein, Human T-cell leukemia virus type I; C066797:transmembrane envelope glycoprotein gp45, retrovirus