Silicone gel breast implants, breast cancer and connective tissue disorders.
Recent worldwide media speculation that silicone gel-filled breast implants may be linked to an increased incidence of breast and other cancers, and connective tissue disease (particularly systemic sclerosis) has caused concern to the medical profession and public alike. Until carefully controlled studies have been performed to prove the safety of these implants, the US Food and Drug Administration has restricted their use to research and breast reconstruction. Research has so far failed to prove a causative relationship between silicone implants and cancer or connective tissue disorders.
Park
A J
AJ
Department of Plastic Surgery, St John's Hospital, Livingston, UK.
Black
R J
RJ
Watson
A C
AC
D000818:Animals; D001943:Breast Neoplasms / Q000209:etiology*; D003240:Connective Tissue Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D016462:Mammaplasty; D011183:Postoperative Complications / Q000209:etiology; D019736:Prostheses and Implants / Q000009:adverse effects*; D051381:Rats; D011919:Rats, Inbred Strains; D012828:Silicones / Q000009:adverse effects*
D012828:Silicones