title: The human pancreatic lipase-encoding gene: structure and conservation of an Alu sequence in the lipase gene family.
abstract: The isolation and characterization of the human gene (hPL) encoding pancreatic lipase is reported. The gene has 13 exons dispersed in about 20 kb of genomic DNA. A pseudogene of hPL was also partially characterized. An Alu sequence is conserved in the homologous introns of hPL and the lipoprotein lipase-encoding gene.
authors.affiliation: Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110.
authors.forename: H F
authors.initials: HF
authors.lastname: Sims
authors.forename: M L
authors.initials: ML
authors.lastname: Jennens
authors.forename: M E
authors.initials: ME
authors.lastname: Lowe
mesh_terms: D001483:Base Sequence; D017124:Conserved Sequence; D005091:Exons; D006801:Humans; D007438:Introns; D008049:Lipase / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family; D010179:Pancreas / Q000201:enzymology*; D011487:Protein Conformation; D011544:Pseudogenes; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D008049:Lipase