title: Functional analysis suggests unexpected role for conserved active-site residue in enzyme of known structure.
authors.affiliation: Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
authors.forename: P
authors.initials: P
authors.lastname: Schimmell
mesh_terms: D001665:Binding Sites; D002384:Catalysis; D003843:Deoxycytidine Monophosphate / Q000378:metabolism; D003856:Deoxyuracil Nucleotides / Q000378:metabolism; D016297:Mutagenesis, Site-Directed; D013329:Structure-Activity Relationship; D013940:Thymidylate Synthase / Q000737:chemistry*
chemical_list: D003856:Deoxyuracil Nucleotides; D003843:Deoxycytidine Monophosphate; C007267:2'-deoxyuridylic acid; D013940:Thymidylate Synthase