title: Enhanced pneumonia resolution by inhalation of nitric oxide?
abstract: We present a patient with severe bacteraemic pneumococcal pneumonia associated with severe hypoxaemia, where nitric oxide (NO) 15-40 ppm was added to the inspired gas. Nitric oxide therapy improved gas exchange, reduced pulmonary vasoconstriction and peak airway pressure. The patient survived. We observed an unexpected rapid and complete disappearance of bilateral pulmonary infiltrates during the first 120 h of the 7-day NO inhalation period.
authors.affiliation: Department of Anaesthesiology and Intensive Care, Danderyd University Hospital, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Blomqvist
authors.forename: C J
authors.initials: CJ
authors.lastname: Wickerts
authors.forename: M
authors.initials: M
authors.lastname: Andreen
authors.forename: U
authors.initials: U
authors.lastname: Ullberg
authors.forename: A
authors.initials: A
authors.lastname: Ortqvist
authors.forename: C
authors.initials: C
authors.lastname: Frostell
mesh_terms: D000280:Administration, Inhalation; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000150:complications; D008875:Middle Aged; D009569:Nitric Oxide / Q000008:administration & dosage / Q000627:therapeutic use*; D011018:Pneumonia, Pneumococcal / Q000150:complications / Q000188:drug therapy*
chemical_list: D009569:Nitric Oxide