Synthesis and metabotropic receptor activity of the novel rigidified glutamate analogues (+)- and (-)-trans-azetidine-2,4-dicarboxylic acid and their N-methyl derivatives.
Kozikowski
A P
AP
Neurochemistry Research, Mayo Foundation, Jacksonville, Florida 32224.
Tückmantel
W
W
Liao
Y
Y
Manev
H
H
Ikonomovic
S
S
Wroblewski
J T
JT
D001383:Azetidinecarboxylic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D002478:Cells, Cultured; D002531:Cerebellum / Q000187:drug effects / Q000378:metabolism; D005971:Glutamates / Q000138:chemical synthesis* / Q000494:pharmacology; D008745:Methylation; D008968:Molecular Conformation; D016202:N-Methylaspartate / Q000494:pharmacology; D010716:Phosphatidylinositols / Q000378:metabolism; D017470:Receptors, Glutamate / Q000187:drug effects / Q000378:metabolism*
D005971:Glutamates; D010716:Phosphatidylinositols; D017470:Receptors, Glutamate; D001383:Azetidinecarboxylic Acid; D016202:N-Methylaspartate