Isolated peripheral nerve relapse masquerading as Guillain-Barré syndrome in a patient with acute lymphoblastic leukemia.
We report a 30 year old patient with acute lymphoblastic leukemia (ALL) whose leukemic relapse presented as an isolated symmetrical peripheral neuropathy with facial diplegia. Initially, this was consistent with a Guillain-Barré syndrome but the peripheral nerve biopsy revealed leukaemic infiltration. This was followed by a systemic relapse. Reports of peripheral nerve infiltration are scarce and to the best of our knowledge this is the first documented case of peripheral polyneuropathy as a presenting manifestation of ALL relapse.
Boiron
J M
JM
Unité de Greffe de Moëlle, Hopital Haut-Lévêque, Pessac, France.
Ellie
E
E
Vital
A
A
Lagueny
A
A
Vital
C
C
Julien
J
J
Reiffers
J
J
D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D017254:Leukemic Infiltration / Q000175:diagnosis*; D010525:Peripheral Nerves / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis*; D011129:Polyradiculoneuropathy / Q000175:diagnosis*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D012008:Recurrence