title: [Drug-induced syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Review of literature].
abstract: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is caused by an incapacity of plasmatic hypotonia to inhibit antidiuretic hormone (ADH) secretion. This phenomenon leads to a water retention and an expanded extracellular fluid volume, and secondary to a dilution of plasmatic sodium and also to a renal loss of sodium. The SIADH is a relatively rare syndrome, which may occur in various circumstances: central nervous system diseases, cancers, infections... Sometimes, it may be observed as a drug-related side effect: carbamazepine, chlorpropamide, antidepressors, anticancer drugs are particularly involved.
authors.affiliation: Service de Biochimie Médicale, Cliniques Universitaires St-Luc, Bruxelles, Belgique.
authors.forename: L
authors.initials: L
authors.lastname: Verstraeten
authors.forename: B
authors.initials: B
authors.lastname: Dewier
authors.forename: C
authors.initials: C
authors.lastname: Montjoie
authors.forename: A
authors.initials: A
authors.lastname: Hassoun
mesh_terms: D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000139:chemically induced*