title: Factor structure and scoring of the SKT test battery.
abstract: The SKT (Syndrom Kurztest) has been used in the assessment of treatment responses in numerous clinical trials for treatment of dementia in German-speaking Europe. Data from 265 patients with mild to moderate Alzheimer's disease in a study conducted in the U.S. were analyzed to evaluate factor structure, common and specific subtest content, reliability, and concurrent validity. Results confirm the presence of two primary factors of memory and attention. Test-retest reliability of the factor scores was estimated to be .75 and .93. Test-retest reliability of the composite SKT total score was .90. The correlations between the SKT memory and attention factor scores and the MMSE and ADAS measurements of dementia also support validity with regard to the broader construct of cognitive dysfunction.
authors.affiliation: Du Pont Merck Pharmaceutical Company, Wilmington, DE 19880-0027.
authors.forename: Y S
authors.initials: YS
authors.lastname: Kim
authors.forename: D W
authors.initials: DW
authors.lastname: Nibbelink
authors.forename: J E
authors.initials: JE
authors.lastname: Overall
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D001288:Attention / Q000187:drug effects; D004311:Double-Blind Method; D006801:Humans; D007211:Indoles / Q000627:therapeutic use; D011939:Mental Recall / Q000187:drug effects; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011594:Psychometrics; D011725:Pyridines / Q000627:therapeutic use; D012016:Reference Values
chemical_list: D007211:Indoles; D011725:Pyridines; C061017:linopirdine