title: Primary aldosteronism: new approaches to diagnosis and management.
abstract: Primary aldosteronism remains a diagnostic challenge. Certain immunoassay techniques, simplified diagnostic testing, and the introduction of sensitive imaging techniques have facilitated the diagnosis, but obstacles that remain include a lack of optimal screening methods, low sensitivity and specificity of current diagnostic tests, and a growing number of etiological subgroups. A rational approach to the diagnosis of primary aldosteronism is described, as is the differentiation of the surgically correctable lesion (adenoma) from the other etiological subgroups.
authors.affiliation: Department of Cardiovascular Biology, Cleveland Clinic Foundation, OH 44195.
authors.forename: E L
authors.initials: EL
authors.lastname: Bravo
mesh_terms: D000236:Adenoma / Q000378:metabolism / Q000601:surgery; D000310:Adrenal Gland Neoplasms / Q000378:metabolism / Q000601:surgery; D000450:Aldosterone / Q000378:metabolism; D006801:Humans; D006929:Hyperaldosteronism / Q000175:diagnosis* / Q000628:therapy; D012680:Sensitivity and Specificity
chemical_list: D000450:Aldosterone