[A case of Listeria rhombencephalitis with a secondary vasculitis suggested by MRI].
We reported a rare case of Listeria rhombencephalitis with meningitis. A 48-year-old healthy man suddenly experienced high fever and headache, then he had lower cranial nerve's palsies and mental dysfunction developed during one week period. On admission, his temperature was 38 degrees C. He was slightly delirious and euphoric. He had nuchal rigidity, mild paresthesia over his left cheek to left upper lip, a right sixth nerve palsy, dysphagia, hiccup, nasal voice and left cerebellar ataxia. His tongue deviated toward the right side on protrusion. A CSF culture grew Listeria monocytogenes. Intravenous antibiotic therapy (PIPC, minocycline hydrochloride) produced improvement in one month except for mild paresthesia and dysphagia. He almost recovered after 7 months of illness. Brain MRI on T2 weighted image demonstrated multiple small ischemic lesions in the left lateral medulla, upper pontine tegmentum in the right side, and pontine tegmentum in the left side. These lesions enhanced by Gd. were assumed to be due to the secondary vasculitis. Listeria rhombencephalitis is extremely rare in human beings. To our knowledge only thirteen cases have been reported. In seven cases, post-mortem pathological findings confirmed necrotizing angitis in brainstem. Clinical aspects of Listeria rhombencephalitis were discussed, and the entity of this disease should be considered as a treatable cause of acute progressive brainstem meningoencephalitis.
Tokonami
F
F
Department of Internal Medicine, Kumamoto Rosai Hospital.
Imamura
S
S
Suga
M
M
Tokunaga
K
K
Fukuda
Y
Y
D006801:Humans; D008088:Listeriosis / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D008584:Meningitis, Listeria / Q000150:complications; D008590:Meningoencephalitis / Q000150:complications*; D008875:Middle Aged; D012249:Rhombencephalon; D014657:Vasculitis / Q000175:diagnosis / Q000209:etiology*