title: [Hemoglobin SD disease].
abstract: A 7 year old Kurdish girl presented with a cerebral infarction and a resulting hemiparesis following a blood transfusion. Examination of the blood film suggested sickle cell anaemia. However a simultaneously carried out haemoglobin electrophoresis showed haemoglobin S and haemoglobin D. The diagnosis of haemoglobin SD disease was thereby established. This kind of haemoglobin disorder usually shows a mild clinical manifestation. According to our knowledge such serious cases have not been published before. With this disease the main emphasis is on the prevention of recurrent cerebral infarctions bay a long-term transfusion programme whereas the effects of the cerebral infarction are treated in the usual way.
authors.affiliation: Zentrum für Kinder- und Jugendmedizin, Kreiskrankenhaus Lüdenscheid.
authors.forename: H J
authors.initials: HJ
authors.lastname: Laws
authors.forename: R
authors.initials: R
authors.lastname: Dickerhoff
authors.forename: J
authors.initials: J
authors.lastname: Mayer
authors.forename: B
authors.initials: B
authors.lastname: Köster
mesh_terms: D000755:Anemia, Sickle Cell / Q000175:diagnosis / Q000235:genetics; D001921:Brain / Q000473:pathology; D002544:Cerebral Infarction / Q000175:diagnosis / Q000235:genetics; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006580:Genetic Carrier Screening; D006450:Hemoglobin SC Disease / Q000175:diagnosis / Q000235:genetics*; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D008279:Magnetic Resonance Imaging; D013789:Thalassemia / Q000175:diagnosis / Q000235:genetics*
chemical_list: D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal; C026237:hemoglobin D Punjab; C032031:hemoglobin Arab