Maloprim-induced pulmonary eosinophilia.
A 47-year-old woman developed pulmonary eosinophilia from the use of maloprim as malaria prophylaxis. The diagnosis was confirmed by bronchoalveolar lavage (BAL) and transbronchial lung biopsy. Her condition improved with drug withdrawal and steroid therapy. With the increased use of pyrimethamine and dapsone in the treatment of human immunodeficiency syndrome (HIV) infection, this form of drug allergy may become more common.
Begbie
S
S
Department of Internal Medicine, Manly Hospital, Sydney, NSW, Australia.
Burgess
K R
KR
D000962:Antimalarials / Q000009:adverse effects*; D001992:Bronchoalveolar Lavage Fluid / Q000473:pathology; D001999:Bronchoscopy; D003622:Dapsone / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000473:pathology; D011739:Pyrimethamine / Q000009:adverse effects*
D000962:Antimalarials; D004338:Drug Combinations; C001678:Maloprim; D003622:Dapsone; D011739:Pyrimethamine