title: Wound isolate of Salmonella typhimurium that became chlorate resistant after exposure to Dakin's solution: concomitant loss of hydrogen sulfide production, gas production, and nitrate reduction.
abstract: A strain of Salmonella typhimurium isolated from a decubitus ulcer that was being treated topically with half-strength Dakin's solution became H2S negative, nitrate negative, and unable to produce gas from glucose. Experimental data suggested that these effects were associated with the development of chlorate resistance. Thirty-five other strains of Salmonella spp. that were made chlorate resistant also became negative for these three tests.
authors.affiliation: Department of Microbiology and Immunology, University of Western Ontario, London, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Lannigan
authors.forename: Z
authors.initials: Z
authors.lastname: Hussain
mesh_terms: D002704:Chlorates / Q000494:pharmacology*; D004351:Drug Resistance; D005947:Glucose / Q000378:metabolism; D006801:Humans; D006862:Hydrogen Sulfide / Q000378:metabolism*; D008297:Male; D009566:Nitrates / Q000378:metabolism*; D010084:Oxidation-Reduction; D003668:Pressure Ulcer / Q000382:microbiology*; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000378:metabolism; D012973:Sodium Hypochlorite / Q000494:pharmacology*
chemical_list: D002704:Chlorates; D009566:Nitrates; D012973:Sodium Hypochlorite; D005947:Glucose; D006862:Hydrogen Sulfide