Lipoprotein(a) and its role in occlusive vascular disease.
An increased serum level of lipoprotein(a) (LP(a)) is acknowledged as an independent risk factor for occlusive vascular disease, especially atherosclerosis. Recently, a considerable amount of data has been produced on the structure and functional relationships between Lp(a) and the primary cellular interactions of atherosclerosis. In this review we discuss the structure and function of Lp(a) with specific reference to its role in the proposed mechanisms of atherosclerosis.
Tennant
M
M
Department of Anatomy and Human Biology, University of Western Australia, Nedlands.
McGeachie
J K
JK
D001161:Arteriosclerosis / Q000097:blood* / Q000209:etiology; D006801:Humans; D017270:Lipoprotein(a) / Q000097:blood* / Q000737:chemistry; D010958:Plasminogen; D012307:Risk Factors; D013329:Structure-Activity Relationship
D017270:Lipoprotein(a); D010958:Plasminogen