Effects on cell morphology of growing Pseudomonas aeruginosa, Enterobacter cloacae and Staphylococcus aureus in subinhibitory concentrations of p-aminobenzoic acid.
Light microscopy and electron microscopy studies with Enterobacter cloacae, Pseudomonas aeruginosa and Staphylococcus aureus grown in the presence of subinhibitory concentrations of p-aminobenzoic acid indicate that p-aminobenzoic acid may have a direct or indirect effect on the cell walls. The morphological effects of p-aminobenzoic acid varied with different bacterial species. E. cloacae grown in the presence of p-aminobenzoic acid produced filaments while P. aeruginosa cells were elongated and had thicker peripheral cell walls. S. aureus had increased overall cell size and thicker transverse cell walls.
Richards
R M
RM
School of Pharmacy, Robert Gordon University, Aberdeen, Scotland, Great Britain.
Xing
D K
DK
King
T P
TP
D010129:4-Aminobenzoic Acid / Q000494:pharmacology*; D016972:Enterobacter cloacae / Q000166:cytology / Q000187:drug effects*; D008854:Microscopy, Electron; D011550:Pseudomonas aeruginosa / Q000166:cytology / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000166:cytology / Q000187:drug effects*
D010129:4-Aminobenzoic Acid