title: Tracheal intubation after induction of anaesthesia with propofol, alfentanil and i.v. lignocaine.
abstract: We have assessed tracheal intubating conditions in 60 ASA I or II patients after induction of anaesthesia with propofol 2.5 mg kg-1 and alfentanil 10 or 20 micrograms kg-1 with or without i.v. lignocaine 1 mg kg-1. No neuromuscular blocking agents were administered. Patients were allocated randomly to four groups: group 1 = propofol-alfentanil 10 micrograms kg-1; group 2 = propofol-alfentanil 10 micrograms kg-1-lignocaine 1 mg kg-1; group 3 = propofol-alfentanil 20 micrograms kg-1; group 4 = propofol-alfentanil 20 micrograms kg-1-lignocaine 1 mg kg-1. Intubating conditions were assessed as acceptable or unacceptable on the basis of a scoring system dependent on ease of laryngoscopy, vocal cord position and coughing on insertion of the tracheal tube. Intubating conditions were acceptable in 20%, 73%, 73% and 93% of patients in groups 1-4, respectively. Intubating conditions were better and there was less coughing in the lignocaine group.
authors.affiliation: Department of Anaesthesia, Western Infirmary, Glasgow.
authors.forename: J A
authors.initials: JA
authors.lastname: Davidson
authors.forename: J A
authors.initials: JA
authors.lastname: Gillespie
mesh_terms: D000328:Adult; D015760:Alfentanil; D000771:Anesthesia, Intravenous; D003371:Cough; D004311:Double-Blind Method; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007442:Intubation, Intratracheal; D007828:Laryngoscopy; D008012:Lidocaine; D008875:Middle Aged; D015742:Propofol; D014827:Vocal Cords / Q000033:anatomy & histology
chemical_list: D015760:Alfentanil; D008012:Lidocaine; D015742:Propofol