Correlation of the in vitro and in vivo immunosuppressive activity of brequinar sodium.
Eiras-Hreha
G
G
Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California 90211.
Cramer
D V
DV
Cajulis
E
E
Cosenza
C
C
Mills
L
L
Hough
K
K
Frankland
M
M
Chapman
F
F
Wang
H
H
Zajac
I
I
D000818:Animals; D001713:Biphenyl Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D002478:Cells, Cultured; D016572:Cyclosporine / Q000494:pharmacology / Q000627:therapeutic use; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D016027:Heart Transplantation / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D007700:Kinetics; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology* / Q000378:metabolism; D008297:Male; D011743:Pyrimidines / Q000378:metabolism; D051381:Rats; D011912:Rats, Inbred ACI; D011917:Rats, Inbred Lew; D013997:Time Factors; D016042:Transplantation, Heterotopic; D014529:Uridine / Q000494:pharmacology; D011798:Quinaldines
D001713:Biphenyl Compounds; D016572:Cyclosporine; D007166:Immunosuppressive Agents; D011743:Pyrimidines; D014529:Uridine; C046943:brequinar; D011798:Quinaldines