title: Noninfectious risks and new trends in transfusion practice.
abstract: HIV infection and hepatitis are considered major transfusion risks, but there are other serious adverse effects; circulatory overload, acute hemolytic transfusion reaction, and graft-versus-host disease. Each can be minimized by attention to preventative measures. Current transfusion practice emphasizes the appropriate use of selected components, promotion of autologous transfusions, single donor apheresis platelets, and intraoperative blood salvage. Blood cell growth factors are important in the management of patients with production disorders. Tracking of bones and tissues used as allografts will become an important function for health-care facilities.
authors.affiliation: Department of Clinical Pathology, William Beaumont Hospital, Royal Oak, Mich.
authors.forename: R H
authors.initials: RH
authors.lastname: Walker
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001810:Blood Volume; D006086:Graft vs Host Disease / Q000209:etiology; D006461:Hemolysis; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D012769:Shock / Q000209:etiology; D065227:Transfusion Reaction