title: Motion sickness induced by sinusoidal linear acceleration in rats.
abstract: The characteristics of linear acceleration to cause motion sickness of rats were examined using pica as a behavioral index of motion sickness. A vestibular sled was used to generate sinusoidal linear acceleration. At 0.4 Hz and with a peak acceleration of 0.15 G, the effectiveness of linear acceleration in inducing motion sickness was X-axis > Y-axis > Z-axis. At 0.4 Hz and along the X-axis, rats suffered from more severe motion sickness with a high peak G load (0.15 G) than with a low one (0.08 G). Along the X-axis and with a peak acceleration of 0.15 G, the severity of motion sickness was not related to frequency (0.4, 0.6 Hz).
authors.affiliation: Department of Otolaryngology, Osaka University Medical School, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Horii
authors.forename: N
authors.initials: N
authors.lastname: Takeda
authors.forename: M
authors.initials: M
authors.lastname: Morita
authors.forename: T
authors.initials: T
authors.lastname: Kubo
authors.forename: T
authors.initials: T
authors.lastname: Matsunaga
mesh_terms: D000054:Acceleration; D000818:Animals; D004435:Eating; D007616:Kaolin / Q000008:administration & dosage; D008297:Male; D009041:Motion Sickness / Q000209:etiology* / Q000503:physiopathology; D009068:Movement; D051381:Rats; D017208:Rats, Wistar; D012399:Rotation; D012444:Saccule and Utricle / Q000503:physiopathology; D012665:Semicircular Canals / Q000503:physiopathology
chemical_list: D007616:Kaolin