Ocimum sanctum Linn--a study on gastric ulceration and gastric secretion in rats.
The antiulcerogenic property of Ocimum sanctum Linn (Tulsi) was studied in pyloric ligated and pyloric ligated & aspirin treated rats. The extract of OSL reduced the ulcer index, free & total acidity on acute and chronic administration. Seven days pretreatment with the drug increased the mucous secretion also. It may be concluded that OSL extract has antiulcerogenic property against experimental ulcers, and it is due to its ability to reduce acid secretion and increase mucous secretion.
Mandal
S
S
Department of Pharmacology, Burdwan Medical College, West Bengal.
Das
D N
DN
De
K
K
Ray
K
K
Roy
G
G
Chaudhuri
S B
SB
Sahana
C C
CC
Chowdhuri
M K
MK
D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D005260:Female; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007194:India; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000188:drug therapy* / Q000517:prevention & control
D000897:Anti-Ulcer Agents; D010936:Plant Extracts