The role of exposure to animals in the etiology of Campylobacter jejuni/coli enteritis.
To determine the role of animals as possible sources for human infection with Campylobacter jejuni/coli, 218 human cases of Campylobacter enteritis diagnosed among members of Group Health Cooperative of Puget Sound, King County, Washington, from April 1982 through September 1983 were compared with 526 controls, randomly selected from Group Health Cooperative members. All subjects were questioned regarding animal exposures one week prior to illness (cases) or interview (controls). There was no increase in risk for C. jejuni/coli enteritis associated with contact with various animals. However, exposure to diarrheic animals was associated with a fourfold increase in the risk of C. jejuni/coli enteritis (odds ratio = 4.3, 95% confidence interval (CI) 1.9-9.7). Adjustment for potential confounding factors by logistic regression analysis yielded an odds ratio of 3.3 (95% CI 1.2-7.5) associated with such exposure. An estimated 6.3% of cases of C. jejuni/coli enteritis was attributed to exposure to diarrheic animals.
Saeed
A M
AM
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle.
Harris
N V
NV
DiGiacomo
R F
RF
D000293:Adolescent; D000328:Adult; D000818:Animals; D001717:Birds; D002169:Campylobacter Infections / Q000635:transmission* / Q000662:veterinary*; D017000:Campylobacter coli; D016123:Campylobacter jejuni; D002415:Cats; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D004285:Dogs; D004751:Enteritis / Q000382:microbiology*; D005260:Female; D005399:Fishes; D006041:Goats; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012044:Regression Analysis; D012104:Reptiles; D012377:Rodentia; D012756:Sheep; D013552:Swine; D015047:Zoonoses / Q000635:transmission*