title: Relief of sickle cell priapism by hydralazine. Report of a case.
abstract: We report a 16-year-old Tanner IV male with homozygous hemoglobin S who presented with recurrent episodes of priapism unresponsive to standard therapy with hydration, analgesia, and exchange transfusion. He had a complete resolution of his symptoms with hydralazine therapy. We therefore suggest a trial of vasodilator therapy for recurrent sickle cell priapism before attempting surgical therapy.
authors.affiliation: Division of Hematology, McGill University, Montreal, Quebec, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Baruchel
authors.forename: J
authors.initials: J
authors.lastname: Rees
authors.forename: M L
authors.initials: ML
authors.lastname: Bernstein
authors.forename: P
authors.initials: P
authors.lastname: Goodyer
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000628:therapy; D003131:Combined Modality Therapy; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use*; D008297:Male; D015995:Prevalence; D011317:Priapism / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D012008:Recurrence
chemical_list: D006830:Hydralazine