title: Information processing and gene expression.
abstract: The process by which information is transferred from DNA to RNA to protein accommodates the further editing and altering of information, particularly in messenger RNA. From one gene, a cell may derive different protein products by altering the information content of mRNA to accommodate the very specialized functions of the cell. Information processing in the form of posttranscriptional RNA processing allows for incredible complexity and differentiation of tissue and tissue function. Most importantly, the posttranscriptional processing of mRNA does not alter the indelible information stored in the DNA which must be maintained and passed on from one generation to the next. Rather, the alteration of information occurs during the transient flow of information from DNA to RNA at the level of messenger RNA. Developmental and differentiation processes are dependent on this information processing which endows the cell with another level of control in gene expression.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of South Florida College of Medicine.
authors.forename: D C
authors.initials: DC
authors.lastname: Eichler
mesh_terms: D000818:Animals; D015870:Gene Expression; D006801:Humans; D012323:RNA Processing, Post-Transcriptional; D012326:RNA Splicing; D012333:RNA, Messenger / Q000378:metabolism*
chemical_list: D012333:RNA, Messenger