title: [Perfusion imaging with 99mTc PPN-1011 for the assessment of myocardial area at risk and the efficacy of PTCA/PTCR in myocardial infarction and unstable angina].
abstract: The determination of the myocardium at risk before intervention and the change in that region after intervention constitute a promising measurement tool for the assessment of acute therapy. We used 99mTc PPN-1011 in 4 patients with acute myocardial ischemia (2 patients with acute myocardial infarction, 2 unstable angina) and subsequent successful reperfusion. All 4 patients had perfusion defect on the pre-reperfusion image. Perfusion abnormality on post-reperfusion image was all improved significantly compared with pre-reperfusion image, suggesting the efficacy of acute treatment in acute myocardial ischemia. We conclude that 99mTc PPN-1011 scintigraphy is useful method for the assessment of myocardial area at risk and the efficacy of PTCA/PTCR in myocardial infarction and unstable angina.
authors.affiliation: Division of Cardiology and Radiology, Prefectural Gifu Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Nishida
authors.forename: S
authors.initials: S
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Matsuo
authors.forename: Y
authors.initials: Y
authors.lastname: Kotoo
authors.forename: H
authors.initials: H
authors.lastname: Oda
authors.forename: T
authors.initials: T
authors.lastname: Matsubara
authors.forename: A
authors.initials: A
authors.lastname: Sugiyama
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuno
authors.forename: M
authors.initials: M
authors.lastname: Kano
authors.forename: S
authors.initials: S
authors.lastname: Tanihata
mesh_terms: D000368:Aged; D000789:Angina, Unstable / Q000000981:diagnostic imaging* / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000628:therapy; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012306:Risk; D015912:Thrombolytic Therapy
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; C078700:technetium tc-99m tetrofosmin