Circulating CA-125 levels in superovulated women are mainly derived from the ovaries.
A prospective study was designed to determine the individual contribution of the ovaries and the endometrium to total circulating levels of CA-125. Luteal phase CA-125 levels were measured in five women superovulated before and after vaginal hysterectomy performed for pelvic relaxation. The difference in the preoperative and postoperative luteal CA-125 levels of superovulated cycles were similar, suggesting a mainly ovarian source for the antigen although endometrial and other sites of contribution cannot be excluded in view of the small number of patients studied.
Gurgan
T
T
Department of Obstetrics and Gynecology, University of Hacettepe, Faculty of Medicine, Ankara, Turkey.
Urman
B
B
Kisnisci
H A
HA
D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D004717:Endometrium / Q000276:immunology; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal; D010053:Ovary / Q000276:immunology*; D011446:Prospective Studies; D013480:Superovulation / Q000276:immunology*
D015295:Antigens, Tumor-Associated, Carbohydrate