title: Interleukin-2 in autologous bone marrow transplantation.
abstract: Interleukin-2 results in the generation of lymphokine activated killer cells which exhibit a potent effect against a wide variety of tumours. Consequently, interleukin-2 therapy has been used to induce a graft versus tumour effect following autologous bone marrow transplantation. Preclinical studies have shown that this results in successful engraftment, and an enhanced reconstitution of the immune system.
authors.forename: B S
authors.initials: BS
authors.lastname: Charak
mesh_terms: D001853:Bone Marrow / Q000187:drug effects; D016026:Bone Marrow Transplantation / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007376:Interleukin-2 / Q000627:therapeutic use*; D015979:Killer Cells, Lymphokine-Activated / Q000276:immunology; D009369:Neoplasms / Q000628:therapy; D014182:Transplantation, Autologous
chemical_list: D007376:Interleukin-2