Use of imipenem in the treatment of pulmonary nocardiosis.
A case of pulmonary nocardiosis with empyema in a 55-year-old man with macroglobulinemic lymphoma is presented. Treatment with imipenem followed by oral trimethoprim-sulfamethoxazole (TMP-SMX) resolved his symptoms and cleared the roentgenographic abnormalities. This case illustrates the clinical potential of imipenem against Nocardia.
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Department of Medical Specialties, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Rolston
K V
KV
D004359:Drug Therapy, Combination; D004653:Empyema / Q000150:complications / Q000188:drug therapy; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D008171:Lung Diseases / Q000150:complications / Q000188:drug therapy*; D008175:Lung Neoplasms / Q000150:complications; D008223:Lymphoma / Q000150:complications; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009617:Nocardia Infections / Q000150:complications / Q000188:drug therapy*; D009616:Nocardia asteroides / Q000187:drug effects / Q000302:isolation & purification; D009894:Opportunistic Infections / Q000150:complications / Q000188:drug therapy; D013274:Stomach Neoplasms / Q000150:complications; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D008258:Waldenstrom Macroglobulinemia / Q000150:complications
D015378:Imipenem; D015662:Trimethoprim, Sulfamethoxazole Drug Combination