title: An enzyme-linked immunosorbent assay for detecting anthrax antibody in white-tailed deer (Odocoileus virginianus): evaluation of anthrax vaccination and sera from free-ranging deer.
abstract: An enzyme-linked immunosorbent assay for anthrax antibody in white-tailed deer (Odocoileus virginianus) was developed and used to evaluate a vaccination study and compare sera from hunter-killed deer in anthrax endemic and non-endemic areas. Deer subcutaneously vaccinated with anthrax avirulent spore vaccine developed specific antibody to protective antigen (PA) which was significantly higher than the non-vaccinated controls at 30, 60, 90, and 240 days post-vaccination. There was no difference between the levels of antibody to PA between deer in anthrax endemic and non-endemic areas.
authors.affiliation: Department of Wildlife and Fisheries Sciences, Texas A&M University, College Station 77843-2258.
authors.forename: M J
authors.initials: MJ
authors.lastname: Peterson
authors.forename: D S
authors.initials: DS
authors.lastname: Davis
authors.forename: J W
authors.initials: JW
authors.lastname: Templeton
mesh_terms: D000818:Animals; D000835:Animals, Wild; D000881:Anthrax / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*; D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000276:immunology; D001408:Bacillus anthracis / Q000276:immunology*; D001428:Bacterial Vaccines / Q000276:immunology*; D003670:Deer; D004196:Disease Outbreaks / Q000662:veterinary; D004797:Enzyme-Linked Immunosorbent Assay; D007074:Immunoglobulin G / Q000097:blood; D013781:Texas / Q000453:epidemiology; D014611:Vaccination / Q000662:veterinary
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D007074:Immunoglobulin G