title: [Application of the concept of fuzzy logistic controller for treatment of hypertension during anesthesia].
abstract: The concept of Zadeh's fuzzy logistic controller was applied to control hypertension during anesthesia, and its clinical usefulness was examined in patients undergoing elective surgery. Arterial blood pressure was determined by use of an automatic blood pressure device. Nicardipine was used as hypotensive drug. Based on the fuzzy control rules, we developed state-action diagram so as to maintain systolic blood pressure at around 130 mmHg. Nicardipine was infused by using a digitally controlled infusion pump, and its infusion rate was changed according to this diagram. Although acute hypertension associated with endotracheal intubation was not significantly attenuated, hypertension associated with either skin incision or endotracheal extubation, where blood pressure increased slowly, was successfully controlled with our system. These results suggest that the application of the concept of fuzzy logistic controller is useful for treatment of hypertension during anesthesia, especially when blood pressure increases slowly.
authors.affiliation: Department of Anesthesiology, Yamaguchi University Hospital, Ube.
authors.forename: S
authors.initials: S
authors.lastname: Oshita
authors.forename: K
authors.initials: K
authors.lastname: Nakakimura
authors.forename: R
authors.initials: R
authors.lastname: Kaieda
authors.forename: T
authors.initials: T
authors.lastname: Murakawa
authors.forename: H
authors.initials: H
authors.lastname: Tamura
authors.forename: I
authors.initials: I
authors.lastname: Hiraoka
mesh_terms: D000758:Anesthesia; D005260:Female; D017143:Fuzzy Logic; D006801:Humans; D006973:Hypertension / Q000517:prevention & control*; D007260:Infusion Pumps; D008297:Male; D008875:Middle Aged; D009529:Nicardipine / Q000008:administration & dosage*
chemical_list: D009529:Nicardipine