title: [A special case of frontal lobe epilepsy].
abstract: We present clinical, electrophysiological and neuropsychological data of a patient with an extraordinary type of frontal lobe epilepsy. In addition to complex partial and secondary generalized seizures the patient had 183 non-convulsive states per day. Chronical electrocorticography via subdural electrodes clearly revealed that the complex partial seizures and the secondary generalized seizures originated within the right frontal lobe. During the non-convulsive states a constantly increasing spike frequency which showed characteristics of secondary bilateral synchrony was noticed within both frontal lobes. After a period of 20-40 min a sudden transition into a clinically generalized seizure occurred. In contrast to the clinical generalization the onset of bilateral motor phenomena was paralleled by a "secondary focalisation" of the pre-existent high frequency interictal bifrontal epileptiform activity within the right frontal lobe.
authors.affiliation: Klinik für Epileptologie, Universität Bonn.
authors.forename: M
authors.initials: M
authors.lastname: König
authors.forename: A
authors.initials: A
authors.lastname: Hufnagel
authors.forename: C
authors.initials: C
authors.lastname: Helmstaedter
authors.forename: C E
authors.initials: CE
authors.lastname: Elger
mesh_terms: D000328:Adult; D004569:Electroencephalography / Q000295:instrumentation; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000503:physiopathology*; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000503:physiopathology*; D017034:Epilepsy, Frontal Lobe / Q000175:diagnosis / Q000503:physiopathology*; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests; D012039:Regional Blood Flow / Q000502:physiology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D015899:Tomography, Emission-Computed, Single-Photon