title: Relationship between negative skin test with Johnin after vaccination and post mortem findings.
abstract: One hundred and seventy-six cattle, vaccinated against paratuberculosis in the first month of life with a whole-cell inactivated vaccine, containing Mycobacterium paratuberculosis suspended in a water/oil emulsion, were tested with intradermal Johnin between the ages of five and 14 months. Negative results in the skin test occurred more frequently in animals found positive in post mortem examinations (P = 0.008) using histological, microscopical and cultural techniques.
authors.affiliation: Department of Large Animal Medicine and Nutrition, State University of Utrecht, The Netherlands.
authors.forename: G H
authors.initials: GH
authors.lastname: Wentink
authors.forename: J H
authors.initials: JH
authors.lastname: Bongers
authors.forename: J H
authors.initials: JH
authors.lastname: Vos
authors.forename: A A
authors.initials: AA
authors.lastname: Zeeuwen
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000276:immunology; D001428:Bacterial Vaccines / Q000276:immunology; D002417:Cattle; D006968:Hypersensitivity, Delayed; D007428:Intradermal Tests / Q000662:veterinary; D016927:Mycobacterium avium subsp. paratuberculosis / Q000276:immunology* / Q000302:isolation & purification; D010283:Paratuberculosis / Q000276:immunology* / Q000473:pathology / Q000517:prevention & control; D014611:Vaccination / Q000662:veterinary*; D015164:Vaccines, Inactivated
chemical_list: D001426:Bacterial Proteins; D001428:Bacterial Vaccines; D015164:Vaccines, Inactivated