Peptides corresponding to the CD8 binding region of HLA class I block the differentiation of cytotoxic T lymphocyte precursors.
Krensky
A M
AM
Department of Pediatrics, Stanford University, CA 94305.
Lyu
S C
SC
Pouletty
P
P
Benjamin
R
R
Parham
P
P
Clayberger
C
C
D000818:Animals; D001665:Binding Sites; D016827:CD8 Antigens / Q000378:metabolism*; D016466:CHO Cells; D002454:Cell Differentiation / Q000187:drug effects*; D002460:Cell Line; D006224:Cricetinae; D003602:Cytotoxicity, Immunologic; D015789:HLA-A2 Antigen / Q000737:chemistry / Q000235:genetics / Q000276:immunology*; D016297:Mutagenesis, Site-Directed; D010446:Peptide Fragments / Q000138:chemical synthesis / Q000276:immunology / Q000494:pharmacology; D017433:Protein Structure, Secondary; D013601:T-Lymphocytes / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000166:cytology* / Q000187:drug effects / Q000276:immunology; D014162:Transfection
D016827:CD8 Antigens; D015789:HLA-A2 Antigen; D010446:Peptide Fragments