title: Bilateral medial medullary infarction: magnetic resonance imaging and correlative histopathologic findings.
abstract: Bilateral medial medullary infarction is a rare event which clinically presents with flaccid tetraplegia sparing the face, bilateral disturbance of deep sensation, hypoglossal nerve palsy and respiratory failure. We here report a patient with such symptoms in whom magnetic resonance imaging enabled the detection of signal abnormalities in the lower brainstem as soon as 9 h after onset. Results of a control study 3 weeks later correlated well with the extent of infarction that was seen at autopsy. Early lesion detection in the lower medulla by magnetic resonance imaging and the unfavorable prognosis of patients with ischemic damage at that location may provide the rationale for aggressive therapeutic strategies in such a condition.
authors.affiliation: Department of Neurology, Karl-Franzens University, Graz, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Kleinert
authors.forename: F
authors.initials: F
authors.lastname: Fazekas
authors.forename: R
authors.initials: R
authors.lastname: Kleinert
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
authors.forename: F
authors.initials: F
authors.lastname: Payer
authors.forename: H
authors.initials: H
authors.lastname: Offenbacher
authors.forename: H
authors.initials: H
authors.lastname: Lechner
mesh_terms: D002544:Cerebral Infarction / Q000175:diagnosis* / Q000473:pathology; D004292:Dominance, Cerebral / Q000502:physiology*; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000175:diagnosis / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008526:Medulla Oblongata / Q000098:blood supply* / Q000473:pathology; D008875:Middle Aged; D009460:Neurologic Examination