title: Actin molecular structure and function.
abstract: The understanding of actin structure and function has been improved by comparing the atomic structure of G-actin, the model of the F-actin structure, and the properties of actin mutants. Several aspects of actin structure have been tested and good progress has been made in mapping its myosin-binding sites. The dynamic properties of actin and genetic evaluation of its cellular function are attracting increasing attention.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Los Angeles 90024-1570.
authors.forename: E
authors.initials: E
authors.lastname: Reisler
mesh_terms: D000199:Actins / Q000737:chemistry* / Q000235:genetics / Q000502:physiology; D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism; D001665:Binding Sites; D002148:Calmodulin-Binding Proteins / Q000378:metabolism; D002465:Cell Movement; D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics; D008840:Microfilament Proteins / Q000378:metabolism; D009119:Muscle Contraction; D009218:Myosins / Q000378:metabolism; D011485:Protein Binding; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D014335:Tropomyosin / Q000378:metabolism; D014336:Troponin / Q000378:metabolism; D019210:Troponin I
chemical_list: D000199:Actins; D001426:Bacterial Proteins; D002148:Calmodulin-Binding Proteins; D005656:Fungal Proteins; D008840:Microfilament Proteins; D014335:Tropomyosin; D014336:Troponin; D019210:Troponin I; D009218:Myosins