title: Prevention of adhesion formation around the internal mammary artery pedicle by Gore-Tex surgical membrane. An experimental study in goats.
abstract: The effects of wrapping the internal mammary artery in Gore-Tex surgical membrane on the formation of adhesions were investigated. In seven goats both internal mammary arteries were dissected free from the thoracic wall. In six goats the internal mammary arteries were wrapped in Gore-Tex surgical membrane. In the remaining animal both arteries were removed and used as controls. After 6 months the goats were reoperated and it was found that the wrapped segments of all arteries were completely free of adhesions, whereas the non-wrapped segments showed severe adhesion formation. Histologic examination could not detect differences between the wrapped arteries and the controls. One of the 12 wrapped arteries was occluded by a longer existing thrombus, which is attributed to the surgical technique and the fact that postoperatively no anticoagulation was given. The beneficial effect of the use of Gore-Tex surgical membrane on the prevention of adhesion formation is excellent and this implies that it could be used in coronary artery bypass operations, thus reducing the chance of damage to the bypass in case of reoperation.
authors.affiliation: Department of Thoracic and Cardiac Surgery, Nijmegen, The Netherlands.
authors.forename: G L
authors.initials: GL
authors.lastname: Kaan
authors.forename: F
authors.initials: F
authors.lastname: Smedts
authors.forename: J A
authors.initials: JA
authors.lastname: Van Son
authors.forename: J G
authors.initials: JG
authors.lastname: Vincent
authors.forename: K
authors.initials: K
authors.lastname: Kubat
authors.forename: S H
authors.initials: SH
authors.lastname: Skotnicki
authors.forename: L K
authors.initials: LK
authors.lastname: Lacquet
mesh_terms: D000818:Animals; D006041:Goats; D008323:Mammary Arteries / Q000473:pathology; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications / Q000473:pathology / Q000517:prevention & control*; D000267:Tissue Adhesions / Q000473:pathology / Q000517:prevention & control
chemical_list: D011138:Polytetrafluoroethylene