title: Aspiration biopsy cytology of primary bone lesions.
abstract: Fine needle aspiration cytology of 79 primary bone lesions was done, and the clinical and radiologic features were correlated with cytopathology. Seventy-four of these cases were primary malignant bone tumors, two cases each were tumor-like or inflammatory lesions, and one case was a benign bone tumor. Osteosarcoma (37.7%) and Ewing's sarcoma (15.6%) were the most common primary lesions. Correlation with histopathology was possible in 37 cases, and an accuracy rate of 94.1% was achieved. There was an 89% correlation between radiologic and cytologic diagnoses. It was concluded that in this oncology center a working diagnosis based on cytology was possible in almost all cases after correlating with the radiologic findings. However, when there was a discrepancy between the clinical, radiologic and cytologic diagnoses, an open biopsy was mandatory.
authors.affiliation: Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, India.
authors.forename: R V
authors.initials: RV
authors.lastname: Kumar
authors.forename: C R
authors.initials: CR
authors.lastname: Rao
authors.forename: D
authors.initials: D
authors.lastname: Hazarika
authors.forename: G
authors.initials: G
authors.lastname: Mukherjee
authors.forename: B M
authors.initials: BM
authors.lastname: Gowda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods; D001859:Bone Neoplasms / Q000473:pathology* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008223:Lymphoma / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D012516:Osteosarcoma / Q000473:pathology* / Q000628:therapy; D012512:Sarcoma, Ewing / Q000473:pathology* / Q000628:therapy