title: Growth factors: regulation of normal and neoplastic growth.
abstract: This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.
authors.affiliation: University of Oxford, Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, U.K.
authors.forename: L
authors.initials: L
authors.lastname: Pusztai
authors.forename: C E
authors.initials: CE
authors.lastname: Lewis
authors.forename: J
authors.initials: J
authors.lastname: Lorenzen
authors.forename: J O
authors.initials: JO
authors.lastname: McGee
mesh_terms: D002455:Cell Division / Q000502:physiology; D006131:Growth Inhibitors / Q000378:metabolism; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000378:metabolism*
chemical_list: D006131:Growth Inhibitors; D006133:Growth Substances