Objective and subjective efficacy evaluation of various polymer-based saliva substitutes.
Various polymer solutions with and without surfactants were evaluated regarding their lubricating properties on the oral mucosa. After rinsing with the solutions, the oral mucosal friction value was registered with a probe (objective effect). After each rinsing occasion at home, the patients answered a questionnaire (subjective effect). None of the tested polymers showed a longer, clinically significant effect than the other ones. Some of them had the same effect as substitutes available on the Swedish market.
Olsson
H
H
Department of Oral Surgery and Oral Medicine, Faculty of Odontology, Lund University, Malmö, Sweden.
Axéll
T
T
Carlsson
A
A
Bogentoft
C
C
D002482:Cellulose / Q000031:analogs & derivatives / Q000627:therapeutic use; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D012463:Saliva / Q000378:metabolism; D012464:Saliva, Artificial / Q000627:therapeutic use*; D013501:Surface-Active Agents / Q000627:therapeutic use; D011795:Surveys and Questionnaires; D014783:Viscosity; D014987:Xerostomia / Q000628:therapy*
D012464:Saliva, Artificial; D013501:Surface-Active Agents; D002482:Cellulose; C068339:ethyl-2-hydroxyethylcellulose