title: Tityus serrulatus scorpion venom toxins display a complex pattern of antigenic reactivity.
abstract: The antigenic properties of alpha-type and beta-type toxins purified from Tityus serrulatus (Ts) venom were analysed by radioimmunoassay, using rabbit antibodies raised against Ts VII, the main beta-type toxin in the venom, and against Ts IV, an alpha-type toxin. The anti-Ts VII serum did not recognize either the other beta-toxins Ts I and Ts II or the alpha-toxin Ts IV; the anti-Ts IV serum did not bind any of the three beta-toxins Ts I, Ts II or Ts VII. Thus, Tityus toxins display at least three distinct antigenic reactivity patterns.
authors.affiliation: Departamento de Bioquimica e Immunologia, Instituto de Ciencias Biologicas, Belo Horizonte, M.G, Brazil.
authors.forename: M E
authors.initials: ME
authors.lastname: De Lima
authors.forename: M F
authors.initials: MF
authors.lastname: Martin-Eauclaire
authors.forename: C
authors.initials: C
authors.lastname: Chavez-Olortegui
authors.forename: C R
authors.initials: CR
authors.lastname: Diniz
authors.forename: C
authors.initials: C
authors.lastname: Granier
mesh_terms: D000941:Antigens / Q000276:immunology*; D001667:Binding, Competitive; D003429:Cross Reactions; D011863:Radioimmunoassay; D012604:Scorpion Venoms / Q000276:immunology*
chemical_list: D000941:Antigens; D012604:Scorpion Venoms; C003609:tityustoxin