Treatment of T3a bladder cancer with iridium implantation.
A total of 7 patients with high grade, T3a (Stage B2) bladder cancer were treated with external radiation therapy and interstitial iridium implantation from May 1986 through March 1988. Follow-up has ranged from nineteen to sixty-one months with a median of forty months. One patient has required a cystectomy and is currently free of disease, and 1 patient has had recurrence of his cancer and metastatic carcinoma has developed; 5 are free of disease and have maintained their usual state of bladder function. Iridium implantation maintains bladder function and is effective therapy for selected individuals with localized, muscle-invading bladder cancer.
Grossman
H B
HB
Department of Surgery, University of Michigan, Ann Arbor.
Sandler
H M
HM
Perez-Tamayo
C
C
D000368:Aged; D001918:Brachytherapy; D002295:Carcinoma, Transitional Cell / Q000453:epidemiology / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000532:radiotherapy*
D007496:Iridium Radioisotopes