Ga-67 scintigraphy after bone marrow harvest. Significance of "sacroiliac" asymmetry in the lymphoma patient.
The importance of recognizing asymmetric Ga-67 citrate uptake in the sacroiliac region after bone marrow harvest and transplant is discussed in a case of non-Hodgkin's lymphoma. The patient underwent chemotherapy, irradiation, and autologous bone marrow transplant for stage IV disease. Ga-67 scintigraphy revealed sacroiliac asymmetry suggesting medial iliac reparative changes after bone marrow harvest. Iliac bone marrow biopsy showed no evidence of infection or of recurrent tumor. Subsequent follow-up imaging and open biopsy demonstrated lymphomatous invasion of adjacent soft tissue where initial findings were thought to represent benign, postharvest changes.
Larar
G N
GN
Department of Radiology, Dana Farber Cancer Institute, Boston, Massachusetts 02115.
Janicek
M J
MJ
Kaplan
W D
WD
D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D005710:Gallium Radioisotopes / Q000493:pharmacokinetics; D006801:Humans; D007085:Ilium / Q000000981:diagnostic imaging* / Q000378:metabolism; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D009361:Neoplasm Invasiveness; D011877:Radionuclide Imaging; D012447:Sacrum / Q000000981:diagnostic imaging* / Q000378:metabolism; D014182:Transplantation, Autologous
D005710:Gallium Radioisotopes