title: Objective and subjective efficacy evaluation of various polymer-based saliva substitutes.
abstract: Various polymer solutions with and without surfactants were evaluated regarding their lubricating properties on the oral mucosa. After rinsing with the solutions, the oral mucosal friction value was registered with a probe (objective effect). After each rinsing occasion at home, the patients answered a questionnaire (subjective effect). None of the tested polymers showed a longer, clinically significant effect than the other ones. Some of them had the same effect as substitutes available on the Swedish market.
authors.affiliation: Department of Oral Surgery and Oral Medicine, Faculty of Odontology, Lund University, Malmö, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Olsson
authors.forename: T
authors.initials: T
authors.lastname: Axéll
authors.forename: A
authors.initials: A
authors.lastname: Carlsson
authors.forename: C
authors.initials: C
authors.lastname: Bogentoft
mesh_terms: D002482:Cellulose / Q000031:analogs & derivatives / Q000627:therapeutic use; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D012463:Saliva / Q000378:metabolism; D012464:Saliva, Artificial / Q000627:therapeutic use*; D013501:Surface-Active Agents / Q000627:therapeutic use; D011795:Surveys and Questionnaires; D014783:Viscosity; D014987:Xerostomia / Q000628:therapy*
chemical_list: D012464:Saliva, Artificial; D013501:Surface-Active Agents; D002482:Cellulose; C068339:ethyl-2-hydroxyethylcellulose