Fetal anaemia and its relation with increased concentrations of adenosine.
Adenosine concentrations were measured in umbilical venous blood obtained by cordocentesis from 14 fetuses of 19-34 weeks' gestation. The concentration did not change significantly with gestational age, but anaemic fetuses showed significantly increased concentrations of adenosine and there was a positive association with blood oxygen tension. These findings suggest that the fetus responds to tissue hypoxia by increasing blood adenosine concentrations from at least 19 weeks' gestation.
Ross Russell
R I
RI
Department of Child Health, Kings College Hospital, London.
Greenough
A
A
Lagercrantz
H
H
Dahlin
I
I
Nicolaides
K
K
D000241:Adenosine / Q000097:blood*; D000740:Anemia / Q000097:blood*; D017218:Cordocentesis; D003430:Cross-Sectional Studies; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005315:Fetal Diseases / Q000097:blood*; D005865:Gestational Age; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D011247:Pregnancy
D006454:Hemoglobins; D000241:Adenosine