title: Virulence factors in endometrial cancer.
abstract: The majority of endometrial cancers are relatively benign and curable; there is a subset of virulent tumors that demands recognition. Factors that must be evaluated include: tumor grade, ploidy, steroid receptors, myometrial invasion, lymph node status, extrauterine disease or positive peritoneal fluid, and certain special tumors. These tumors of special virulence include: papillary adenocarcinoma, papillary serous adenocarcinoma, adenosquamous carcinoma, and clear cell carcinoma. Virulent tumors (approximately 20%) require special consideration and special treatment.
authors.affiliation: Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, New York, New York.
authors.forename: S B
authors.initials: SB
authors.lastname: Gusberg
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000231:Adenocarcinoma, Papillary / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003536:Cystadenocarcinoma / Q000473:pathology; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D014594:Uterine Neoplasms / Q000473:pathology*