Cardiac conduction abnormalities during carbamazepine therapy for neuralgia following Guillain-Barré syndrome.
A 61-year-old man without previous medical history was admitted for Guillain-Barré syndrome (GBS). Carbamazepine was prescribed on day 72 for dysesthesia occurring at the time of recovery. Subsequently, severe cardiac conduction disturbances (asystole, atrioventricular block) were observed and a permanent pacemaker had to be inserted. The possible relationship between carbamazepine therapy and cardiac side effects is discussed in this condition, as GBS itself is often complicated by cardiac arrhythmias.
Hantson
P
P
Department of Intensive Care Medicine, Cliniques Universitaires St-Luc, Brussels, Belgium.
Ilunga
K
K
Martin
N
N
Ziade
D
D
Evenepoel
M
M
Cojocaru
M
M
Mahieu
P
P
D002220:Carbamazepine / Q000009:adverse effects*; D006323:Heart Arrest / Q000139:chemically induced*; D006327:Heart Block / Q000139:chemically induced* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D011129:Polyradiculoneuropathy / Q000188:drug therapy*
D002220:Carbamazepine