Cholesterol uptake in the human intestine. Hypo- and hyperresponsiveness.
Cholesterol uptake was studied at the small intestine biopsies taken from patients without intestinal malfunction. Three distinct groups of patients were described: those with low (146 +/- 19) nmol/mm2 per 2 h), medium (455 +/- 18 nmol/mm2 per 2 h) and high (833 +/- 24 nmol/mm2 per 2 h) rates of cholesterol uptake. Positive correlation between cholesterol uptake and intestinal cholesterol synthesis was observed in the last two groups.
Safonova
I G
IG
Institute of Experimental Cardiology, Cardiology Research Center, Moscow, Russia.
Sviridov
D D
DD
Roytman
A
A
Rytikov
F M
FM
Dolgov
V V
VV
Nano
J L
JL
Rampal
P
P
Repin
V S
VS
D000085:Acetates / Q000378:metabolism; D002250:Carbon Radioisotopes; D002784:Cholesterol / Q000096:biosynthesis* / Q000378:metabolism*; D046508:Culture Techniques; D006801:Humans; D007421:Intestine, Small / Q000378:metabolism*; D007700:Kinetics
D000085:Acetates; D002250:Carbon Radioisotopes; D002784:Cholesterol