Influence of haptic materials on the adherence of staphylococci to intraocular lenses.
A recent case-control study indicated that the insertion of an intraocular lens with polypropylene (Prolene) haptic materials was a significant risk factor for postoperative endophthalmitis (odds ratio = 4.5, P < .01). In the present study, we used quantitative techniques to evaluate adherence of Staphylococcus epidermidis to two intraocular lens types--lenses with polypropylene haptic materials and all-polymethyl methacrylate optic and three-piece all-polymethyl methacrylate lenses--using a quantitative culture method, a radioisotope technique, and scanning electron microscopy. All three methods demonstrated approximately twice as many bacteria adherent to lenses with polypropylene haptic materials as to all-polymethyl methacrylate lenses. Scanning electron microscopy showed preferential bacterial adherence to the polypropylene haptic materials. These data provide a pathogenic mechanism to explain our epidemiologic findings of an increased risk of postoperative endophthalmitis associated with implantation of intraocular lenses with polypropylene haptic materials.
Raskin
E M
EM
Department of Ophthalmology, New York Eye and Ear Infirmary, NY 10003.
Speaker
M G
MG
McCormick
S A
SA
Wong
D
D
Menikoff
J A
JA
Pelton-Henrion
K
K
D000327:Adsorption; D001422:Bacterial Adhesion; D015169:Colony Count, Microbial; D009877:Endophthalmitis / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology; D004866:Equipment Contamination; D007553:Isotope Labeling; D007910:Lenses, Intraocular / Q000592:standards*; D008422:Materials Testing; D020366:Methylmethacrylate; D008768:Methylmethacrylates / Q000592:standards; D008855:Microscopy, Electron, Scanning; D011126:Polypropylenes / Q000592:standards*; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology; D012307:Risk Factors; D013010:Sonication; D013212:Staphylococcus epidermidis / Q000254:growth & development / Q000302:isolation & purification
D008768:Methylmethacrylates; D011126:Polypropylenes; D020366:Methylmethacrylate