Exstrophy of the cloaca in a 47,XXX child: review of genitourinary malformations in triple-X patients.
Cloacal exstrophy, unilateral renal agenesis, and Müllerian anomalies occurred in a liveborn infant with a 47,XXX chromosome constitution. The patient extends the range of genitourinary anomalies reported in triple-X patients. Screening asymptomatic patients for urinary tract abnormalities may be useful in searching for silent malformations potentially associated with this karyotype.
Lin
H J
HJ
Department of Pediatrics, Harbor-UCLA Medical Center, Torrance 90502.
Ndiforchu
F
F
Patell
S
S
D000015:Abnormalities, Multiple / Q000235:genetics; D001006:Anus, Imperforate / Q000235:genetics; D002988:Cloaca / Q000002:abnormalities*; D005260:Female; D006554:Hernia, Umbilical / Q000235:genetics; D006801:Humans; D007223:Infant; D007668:Kidney / Q000002:abnormalities; D010053:Ovary / Q000002:abnormalities; D014314:Trisomy; D014564:Urogenital Abnormalities; D014599:Uterus / Q000002:abnormalities; D014960:X Chromosome