title: [Spontaneous rupture of the left hepatic duct].
abstract: A previously well 24-year-old man complained of persistent epigastric pain after a session of intensive muscle building exercise especially of the abdominal muscles. The abdomen was diffusely tender without guarding. There was an increased concentration of bilirubin (64.7 mumol/l), GOT (117 U/l), GPT (529 U/l) and alkaline phosphatase (150 U/l). Ultrasound examination showed a widening of the choledochal duct to 11 mm without signs of gallstones. Endoscopic retrograde cholangiography additionally revealed contrast-medium extravasation from the left hepatic duct. Computed tomography, performed immediately afterwards, confirmed the extravasation, while liver and pancreas were unremarkable. Laparoscopy revealed a 5 mm tear in the left hepatic duct, close to the hepatic duct bifurcation with bile effusion into the peritoneal cavity. The latter was rinsed endoscopically with Ringer's solution and drains were placed in the omental bursa and subhepatically in the region of the bile leak. To relax the sphincter Oddi glycerol trinitrate was administered postoperatively, for the first five days 72 mg/24 h intravenously, then for nine days twice daily 20 mg by month. No more bile drained as early as the second postoperative day and the patient was free of symptoms 2 weeks later.
authors.affiliation: Departement Medizinische Radiologie, Universitätsspital Zürich.
authors.forename: M F
authors.initials: MF
authors.lastname: Müller
authors.forename: G P
authors.initials: GP
authors.lastname: Krestin
authors.forename: W
authors.initials: W
authors.lastname: Weder
authors.forename: R
authors.initials: R
authors.lastname: Münch
authors.forename: A
authors.initials: A
authors.lastname: Wegmann
mesh_terms: D000328:Adult; D001649:Bile Duct Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde; D006500:Hepatic Duct, Common / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D012422:Rupture, Spontaneous; D014057:Tomography, X-Ray Computed; D014891:Weight Lifting / Q000293:injuries