title: The use of cultured epithelial autografts in the wound care of severely burned patients.
abstract: Commercially prepared cultured epithelial autografts permit closure of deep burn wounds when insufficient uninjured skin is available for split-thickness grafting. This technique was used in seven patients with a mean total body surface area (TBSA) burn of 66% and full-thickness burn of 52%. All patients survived with a mean initial take of 69% and final take of 80% for the cultured epithelial autografts. Patients with a TBSA burn greater than 80% required at least a second application of the grafts. We feel our approach to wound preparation and postoperative wound care has contributed to our success with this technique.
authors.affiliation: Department of Surgery, Akron General Medical Center, OH.
authors.forename: K G
authors.initials: KG
authors.lastname: McAree
authors.forename: R L
authors.initials: RL
authors.lastname: Klein
authors.forename: C R
authors.initials: CR
authors.lastname: Boeckman
mesh_terms: D016475:3T3 Cells; D000293:Adolescent; D000328:Adult; D000818:Animals; D001706:Biopsy; D001830:Body Surface Area; D002056:Burns / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002478:Cells, Cultured; D002648:Child; D004848:Epithelium / Q000254:growth & development / Q000637:transplantation; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006085:Graft Survival; D006776:Hospitals, Pediatric; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D051379:Mice; D008875:Middle Aged; D009820:Ohio / Q000453:epidemiology; D012086:Reoperation / Q000706:statistics & numerical data; D016038:Skin Transplantation / Q000379:methods / Q000592:standards*; D015996:Survival Rate; D014182:Transplantation, Autologous / Q000379:methods / Q000592:standards*; D016896:Treatment Outcome