title: Mechanisms of supraspinal correction of locomotor activity generator.
abstract: In experiments on immobilized decerebrate cats, data about reorganization of efferent activity parameters of the forelimb and hindlimb locomotor generators evoked by electrical stimulation of descending systems were obtained. The generators controlling both forelimb and hindlimb locomotor movements were found to be characterized by the existence of stable states at which total influence of different descending systems on these generators was extremely limited. These data enable us to conclude that the sense of activity reorganization in locomotor generators of both forelimb and hindlimb under the influence of descending system signals is in bringing the motor program to a dynamic relation with supraspinal inflow, where a sufficient degree of limitation and balancing of the influences of corresponding descending systems on the interneuronal nets, determining time and phase characteristics of these generators, is ensured. Possible mechanisms of realization of this interaction between descending signals and locomotor activity generators are discussed.
authors.affiliation: Department of Physiology of the Spinal Cord, A. A. Bogomoletz Institute of Physiology, Ukrainian Academy of Sciences, Kiev.
authors.forename: A M
authors.initials: AM
authors.lastname: Degtyarenko
authors.forename: T V
authors.initials: TV
authors.lastname: Zavadskaya
authors.forename: K V
authors.initials: KV
authors.lastname: Baev
mesh_terms: D000818:Animals; D002415:Cats; D003655:Decerebrate State / Q000503:physiopathology; D004558:Electric Stimulation; D005121:Extremities / Q000502:physiology; D007103:Immobilization; D009043:Motor Activity / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology; D009476:Neurons, Efferent / Q000187:drug effects / Q000502:physiology; D011712:Pyramidal Tracts / Q000502:physiology; D012012:Red Nucleus / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology*; D003689:Vestibular Nucleus, Lateral / Q000166:cytology / Q000502:physiology