title: Risk of bilateral cervical lymph node metastases in papillary thyroid cancer.
abstract: We evaluated the risk of bilateral or contralateral cervical lymph node metastases in 135 patients with papillary thyroid cancer who underwent bilateral neck dissection. We confirmed that bilateral jugular lymph node metastases were frequent in patients with obvious carcinoma in both lobes of the gland, in those with cancers arising in the isthmus, in those with clinically detectable bilateral lymphadenopathy, and in those with recurrent thyroid cancer. However, only 24% of the patients who had cancer clinically confined to one lobe with no bilateral or contralateral lymphadenopathy had histologically detected bilateral or contralateral jugular lymph node metastases. But the occurrence of contralateral jugular lymph node metastases was significantly correlated with both clinical lymphadenopathy in the ipsilateral neck and contralateral paratracheal lymph node metastases. Bilateral lymph dissection might be beneficial for these patients.
authors.affiliation: Department of Surgery II, Kanazawa University Hospital, School of Medicine, Kanazawa University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Noguchi
authors.forename: S
authors.initials: S
authors.lastname: Kinami
authors.forename: K
authors.initials: K
authors.lastname: Kinoshita
authors.forename: H
authors.initials: H
authors.lastname: Kitagawa
authors.forename: M
authors.initials: M
authors.lastname: Thomas
authors.forename: I
authors.initials: I
authors.lastname: Miyazaki
authors.forename: T
authors.initials: T
authors.lastname: Michigishi
authors.forename: Y
authors.initials: Y
authors.lastname: Mizukami
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000556:secondary* / Q000601:surgery; D016009:Chi-Square Distribution; D002648:Child; D005260:Female; D006258:Head and Neck Neoplasms / Q000517:prevention & control / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery