Paralysis of downgaze in two patients with clinical-radiologic correlation.
Selective downgaze paralysis was correlated with discrete bilateral lesions at the mesencephalic-diencephalic junction in a 9-year-old girl following severe pneumococcal meningitis, and in a 64-year-old man who suffered an embolic infarction. Magnetic resonance imaging demonstrated bilateral lesions in the region of the rostral interstitial nucleus of the medial longitudinal fasciculus. Clinical-radiologic correlation allowed identification of the likely vascular cause in both patients.
Green
J P
JP
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Ga.
Newman
N J
NJ
Winterkorn
J S
JS
D002544:Cerebral Infarction / Q000150:complications*; D002648:Child; D004027:Diencephalon / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008586:Meningitis, Pneumococcal / Q000150:complications*; D008636:Mesencephalon / Q000473:pathology*; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D009887:Ophthalmoscopy