title: Circulating CA-125 levels in superovulated women are mainly derived from the ovaries.
abstract: A prospective study was designed to determine the individual contribution of the ovaries and the endometrium to total circulating levels of CA-125. Luteal phase CA-125 levels were measured in five women superovulated before and after vaginal hysterectomy performed for pelvic relaxation. The difference in the preoperative and postoperative luteal CA-125 levels of superovulated cycles were similar, suggesting a mainly ovarian source for the antigen although endometrial and other sites of contribution cannot be excluded in view of the small number of patients studied.
authors.affiliation: Department of Obstetrics and Gynecology, University of Hacettepe, Faculty of Medicine, Ankara, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Gurgan
authors.forename: B
authors.initials: B
authors.lastname: Urman
authors.forename: H A
authors.initials: HA
authors.lastname: Kisnisci
mesh_terms: D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D004717:Endometrium / Q000276:immunology; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal; D010053:Ovary / Q000276:immunology*; D011446:Prospective Studies; D013480:Superovulation / Q000276:immunology*
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate