title: Proton MR spectroscopic characteristics of a presumed giant subcortical heterotopia.
abstract: A newborn presented with a mass replacing the left cerebral hemisphere. Although the internal signal characteristics of the lesion were suggestive of disorganized gray and white matter, a true neoplasia such as a ganglioglioma could not be totally excluded. Biopsy is not recommended in these cases since the results may be misleading. Proton MR spectroscopy was used; this technique also suggested the hamartomatous nature of the lesion. Based on the clinical course and the imaging features, conservative therapy and observation were undertaken instead of surgery. At 6 months of age, the patient is stable and the lesion is unchanged.
authors.affiliation: Department of Radiology, University of North Carolina School of Medicine, Chapel Hill 27599.
authors.forename: M
authors.initials: M
authors.lastname: Castillo
authors.forename: L
authors.initials: L
authors.lastname: Kwock
authors.forename: J
authors.initials: J
authors.lastname: Scatliff
authors.forename: S
authors.initials: S
authors.lastname: Gudeman
authors.forename: R
authors.initials: R
authors.lastname: Greenwood
mesh_terms: D001932:Brain Neoplasms / Q000151:congenital / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002828:Choristoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D014057:Tomography, X-Ray Computed