title: Intramedullary spinal sarcoidosis: clinical and magnetic resonance imaging characteristics.
abstract: We present a retrospective series of the clinical and MRI findings in 16 patients with intramedullary spinal sarcoidosis (ISS), including 12 patients studied with gadolinium-DTPA. The spectrum of MRI findings includes leptomeningeal enhancement, fusiform spinal cord enlargement, focal or diffuse intramedullary disease, and spinal cord atrophy. We present a classification of ISS correlating the clinical progression and the temporal sequence of MRI abnormalities. Improvement occurred in five of 12 patients (42%) treated with immunosuppressive therapy.
authors.affiliation: North Central Neurology, Denville, NJ 07834.
authors.forename: S S
authors.initials: SS
authors.lastname: Junger
authors.forename: B J
authors.initials: BJ
authors.lastname: Stern
authors.forename: S R
authors.initials: SR
authors.lastname: Levine
authors.forename: E
authors.initials: E
authors.lastname: Sipos
authors.forename: J F
authors.initials: JF
authors.lastname: Marti-Masso
mesh_terms: D000328:Adult; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D012507:Sarcoidosis / Q000473:pathology*; D013118:Spinal Cord Diseases / Q000473:pathology*
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA