Respiratory failure due to pulmonary lymphangitis carcinomatosis.
A man with primary lung cancer developed respiratory failure due to lymphangitis carcinomatosis that was diagnosed by transbronchial lung biopsy specimen. After combination chemotherapy with high-dose etoposide and cisplatin (CDDP), he was able to cease oxygen therapy and showed improvement of his lymphangitis carcinomatosis. He received a total dose of 13,400 mg/m2 of etoposide. This case suggested that respiratory failure due to lymphangitis carcinomatosis can be a treatable condition.
Fujita
J
J
First Department of Internal Medicine, Kagawa Medical School, Japan.
Yamagishi
Y
Y
Kubo
A
A
Takigawa
K
K
Yamaji
Y
Y
Takahara
J
J
D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy; D008205:Lymphangitis / Q000150:complications* / Q000188:drug therapy; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000188:drug therapy / Q000209:etiology*
D005047:Etoposide; D002945:Cisplatin; D005472:Fluorouracil