The analgesic activity of Hedyosmum bonplandianum: flavonoid glycosides.
Kaempferol 3-O-[alpha-L-rhamnopyranosyl (1-->6)-beta-D-glucopyranoside] and kaempferol 3-O-[beta-D-glucopyranoside] were isolated from the leaves of Hedyosmum bonplandianum H.B.K. (Chloranthaceae), which is used in Colombian folk medicine as an analgesic. The n-butanol extract and the glycosyl flavonoids isolated exhibited significant analgesic activity in mice.
Cárdenas
L C
LC
Departamento de Química, Orgánica, Facultad de Química, Universidad de Santiago de Compostela, Spain.
Rodríguez
J
J
Villaverde
M C
MC
Riguera
R
R
Cadena
R
R
Otero
J A
JA
D000700:Analgesics / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D002240:Carbohydrate Sequence; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
D000700:Analgesics; D005419:Flavonoids; D006027:Glycosides