title: Effects of microwaves on membranes of hematopoietic cells in their structural and functional organization.
abstract: The role of cell membranes in stimulating and inhibiting the effects of microwaves was investigated in experiments carried out with a suspension of murine bone marrow cells irradiated with microwaves in vitro [f = 2.45 GHz, CW, specific absorption rate (SAR) = 12 W/kg]. Results obtained by means of a structural probe, 2.4-TNS, indicate that no structural changes occur in the region of the protein-lipid interphase under conditions of short-term irradiation with microwaves that induced temperatures in the range 36-45 degrees C (exposure time 315 and 525 s, respectively). Investigation of one functional parameter--the ability to produce hematopoietic colonies in the spleen after transplantation of the bone marrow irradiated in vitro by microwaves--indicated the possibility of affecting stimulatory and inhibitory effects of microwaves by using a blocker of cell receptors, Trimepranol. The role of microwaves as a physical factor interfering in the process of cell proliferation at the level of receptor regulation is discussed.
authors.affiliation: Institute of Biophysics, Czechoslovak Academy of Sciences, Brno.
authors.forename: D
authors.initials: D
authors.lastname: Rotkovská
authors.forename: A
authors.initials: A
authors.lastname: Bartonicková
authors.forename: J
authors.initials: J
authors.lastname: Kautská
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells; D002462:Cell Membrane / Q000502:physiology / Q000528:radiation effects*; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008872:Microwaves