Ophthalmic findings in classical galactosaemia--prospective study.
Thirty three children with classical galactosaemia diagnosed through newborn screening are considered. It is concluded that cataract formation has a direct relationship with poor dietary control. Erythrocyte galactose-1-phosphate (Gal-1-P) levels do not correspond to cataract formation unless many times higher than normal. The value of crystalline lens biomicroscopy is confirmed as a useful method for monitoring the dietary and biochemical control in classical galactosaemia.
Beigi
B
B
Department of Paediatric Ophthalmology, Children's Hospital, Dublin, Ireland.
O'Keefe
M
M
Bowell
R
R
Naughten
E
E
Badawi
N
N
Lanigan
B
B
D002386:Cataract / Q000209:etiology; D002648:Child; D005260:Female; D005693:Galactosemias / Q000150:complications / Q000178:diet therapy / Q000473:pathology*; D005695:Galactosephosphates / Q000097:blood; D006801:Humans; D007908:Lens, Crystalline / Q000473:pathology*; D008297:Male; D010349:Patient Compliance; D011446:Prospective Studies
D005695:Galactosephosphates; C029973:galactose-1-phosphate