Examination of the effects of hemodynamic and pharmacologic interventions on coronary collateral flow in a patient during cardiac catheterization.
The vasomotor response of native human collateral vessels to pharmacologic or hemodynamic vasodilatory stimuli is not well known. We describe a case where retrograde collateral flow velocity was measured both at baseline and following selected hemodynamic and pharmacologic interventions. This index case represents the first in a series of potential human physiologic studies designed to address questions pertaining to control of collateral blood supply in humans.
Donohue
T
T
Cardiology Division, St. Louis University Hospital, Missouri.
Kern
M J
MJ
Bach
R
R
Aguirre
F
F
Wolford
T
T
D000241:Adenosine; D015906:Angioplasty, Balloon, Coronary; D001783:Blood Flow Velocity / Q000502:physiology; D006328:Cardiac Catheterization; D003097:Collateral Circulation / Q000502:physiology*; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D003331:Coronary Vessels / Q000187:drug effects / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin; D014666:Vasomotor System / Q000187:drug effects / Q000502:physiology
D005996:Nitroglycerin; D000241:Adenosine