title: Computer-assisted DREZ microcoagulation: posttraumatic spinal deafferentation pain.
abstract: Our data demonstrate that approximately 23-29% of standard dorsal root entry zone (DREZ) microcoagulation procedures fail to relieve pain due to inadequate thermal lesions and that approximately 39% fail due to insufficient superior extent of lesions. The remaining failures are related to inadequate lesion placement, improper selection of patients, and, rarely, posttraumatic spinal deafferentation pain resulting from other non-DREZ mechanisms. Computer-assisted DREZ microcoagulation is a satisfactory procedure to treat intractable posttraumatic spinal deafferentation pain, brachial plexus avulsion pain, and lumbosacral nerve root avulsion pain. In all these conditions we have identified areas of abnormal focal hyperactivity in the DREZ area. Perhaps this procedure can be applied to other central pain conditions if, using this technique, abnormal focal hyperactivity is demonstrated to be present.
authors.affiliation: Neuroscience Laboratory, Craig Hospital, Englewood, Colorado.
authors.forename: R E
authors.initials: RE
authors.lastname: Edgar
authors.forename: L G
authors.initials: LG
authors.lastname: Best
authors.forename: P A
authors.initials: PA
authors.lastname: Quail
authors.forename: A D
authors.initials: AD
authors.lastname: Obert
mesh_terms: D017115:Catheter Ablation; D002422:Causalgia / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D004564:Electrocoagulation / Q000009:adverse effects / Q000379:methods*; D004594:Electrophysiology; D005069:Evaluation Studies as Topic; D005500:Follow-Up Studies; D006801:Humans; D007796:Laminectomy; D017075:Laser Coagulation; D008866:Microsurgery / Q000009:adverse effects / Q000379:methods*; D015995:Prevalence; D013119:Spinal Cord Injuries / Q000150:complications*; D013126:Spinal Nerve Roots / Q000601:surgery*; D013813:Therapy, Computer-Assisted