Leuprolide acetate and bone mineral density measured by quantitative digitized radiography.
Quantitative digitized radiography uses low-energy photons to measure bone density with precision not available in older techniques. Using this method, lumbar spine density was evaluated in 12 women before and after 6 months of therapy with LA. A 2.9% decrement in mean bone density was documented. The reproducibility of quantitative digitized radiography suggests that this small degree of bone mineral loss is a real phenomenon and not an artifact of measurement. The clinical significance of this degree of bone mineral loss has yet to be established.
Scialli
A R
AR
Department of Obstetrics and Gynecology, Georgetown University Medical Center, Washington, D.C. 20007-2197.
Jestila
K J
KJ
Simon
J A
JA
D000293:Adolescent; D000328:Adult; D015519:Bone Density / Q000187:drug effects*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D016729:Leuprolide / Q000494:pharmacology*; D008875:Middle Aged; D011856:Radiographic Image Enhancement
D016729:Leuprolide