title: [Effect of succinylcholine on serum potassium concentration in children with chronic renal failure].
abstract: Serum potassium (K+) levels were measured after intravenous injection of succinylcholine (SCh) in 10 children with chronic renal failure, 10 normal children aged 1 to 10 years and 10 children with chronic renal failure after pretreatment with pancuronium prior to SCh. Arterial blood gas was maintained within normal ranges. The serum K+ level increased significantly during 10 minutes after SCh in normal children. There was no significant difference between serum K+ levels in normal children and those in children with chronic renal failure. Administration of pancuronium in small doses (20 micrograms.kg-1) prior to SCh (1 mg.kg-1) was not effective to prevent serum K+ elevation completely. Our results indicate that the administration of SCh in children with chronic renal failure might be possible without increasing serum potassium level.
authors.affiliation: Department of Anesthesiology, Tokyo Metropolitan Kiyose Children's Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Kotani
authors.forename: I
authors.initials: I
authors.lastname: Nishio
authors.forename: H
authors.initials: H
authors.lastname: Kou
authors.forename: G
authors.initials: G
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Fukushima
authors.forename: I
authors.initials: I
authors.lastname: Noguchi
mesh_terms: D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000097:blood*; D011188:Potassium / Q000097:blood*; D013390:Succinylcholine / Q000494:pharmacology*
chemical_list: D013390:Succinylcholine; D011188:Potassium