Pain management with intravenous ketorolac.
OBJECTIVE
To report a case in which intravenous ketorolac was used successfully on a chronic basis to treat cancer pain.


METHODS
Clinical and compatibility studies obtained through a computer literature search.


METHODS
We identified five reports that specifically addressed intravenous dosing of ketorolac.


RESULTS
A 41-year-old man received pain relief from intravenous injections of ketorolac for 11 months. As far as we know, there are no other reports in the literature in which intravenous ketorolac has been used on a chronic basis.


CONCLUSIONS
Experience at our institution indicates that intravenous ketorolac is a useful, well-tolerated nonsteroidal antiinflammatory drug that should be investigated further for use in selected pain models.
Miller
L J
LJ
Division of Pharmacy, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Kramer
M A
MA
D000230:Adenocarcinoma / Q000503:physiopathology; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001650:Bile Duct Neoplasms / Q000503:physiopathology; D002908:Chronic Disease; D006801:Humans; D007275:Injections, Intravenous; D020910:Ketorolac; D008297:Male; D010146:Pain / Q000188:drug therapy*; D013997:Time Factors; D014046:Tolmetin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D014046:Tolmetin; D020910:Ketorolac