title: [Hormonal changes in open-angle glaucoma. II. Levels of cortisol and somatotropin in serum].
abstract: Observing interrelation between carbohydrate metabolism disorders and contrainsular mechanisms in a group of 102 glaucomatous patients, a higher level of cortisol in plasma was detected in 40.2% of glaucomatous patients of whom 31% had increased levels of cortisol together with IRI. In isolation the increased level of cortisol occurred in 8.9%. The frequency of increased cortisol level in glaucomatous patients is substantially lower (40.2%) than the frequency of abnormal insulin curves (78%). Increased levels of growth hormone in the group of patients occurred in 9.3% of cases and these were almost always associated with an abnormal immuno-reactive insulin curve (IRI curve). Accordingly, it is evident that hormonal disorders are a major factor in the onset of both diabetes and glaucoma.
authors.affiliation: Ocní klinika lékarské fakulty UK, Plzen.
authors.forename: K
authors.initials: K
authors.lastname: Janousková
authors.forename: P
authors.initials: P
authors.lastname: Tĕsínský
authors.forename: O
authors.initials: O
authors.lastname: Topolcan
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000097:blood* / Q000150:complications; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D013006:Growth Hormone; D006854:Hydrocortisone