title: Polytetrafluoroethylene grafts in infrainguinal arterial revascularization. Factors affecting outcome.
abstract: One hundred thirty-seven polytetrafluoroethylene infrainguinal bypass grafts were performed over 2 years. The results were analyzed using univariate and multivariate analyses. Our operative mortality was 3.2% and the post-operative amputation rate was 5.8%. Forty-eight reconstructions were done for claudication, with a 5-year secondary patency rate of 64%, no early amputations, and a 2.9% (one limb) late amputation rate. Sixty-six reconstructions were done for rest pain with a 5-year secondary patency rate of 58% and a 3-year limb salvage rate of 77%. The 5-year secondary patency rate for 23 patients with trophic changes was 30%, and the 3-year limb salvage rate was 71%. Multivariate analysis identified the ankle-brachial index as the most important independent factor predicting both primary and secondary graft patency. The cumulative primary and secondary patency rates for patients with an ankle-brachial index of less than 0.5 at 78 months was 37% and 46%, respectively; and 57% and 68%, respectively for patients with an ankle-brachial index of 0.5 or more.
authors.affiliation: Department of Surgery, West Virginia University Health Sciences Center/Charleston Area Medical Center.
authors.forename: A F
authors.initials: AF
authors.lastname: AbuRahma
authors.forename: P A
authors.initials: PA
authors.lastname: Robinson
authors.forename: S P
authors.initials: SP
authors.lastname: Stuart
authors.forename: T A
authors.initials: TA
authors.lastname: Witsberger
authors.forename: W A
authors.initials: WA
authors.lastname: Stewart
authors.forename: J P
authors.initials: JP
authors.lastname: Boland
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001158:Arteries / Q000601:surgery; D001807:Blood Vessel Prosthesis / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D011138:Polytetrafluoroethylene