title: Antimicrobial prophylaxis in 'clean' surgery: hernia repair.
abstract: Antimicrobial prophylaxis is not traditionally employed for patients undergoing 'clean' surgery. The true rates of septic complications are grossly under reported for this group of patients, with up to 72% of all complications occurring, undetected by the surgical team, after discharge from hospital. The implied costs of these infections, coupled with the costs to both the patient and the community services, suggest that antimicrobial prophylaxis should be seriously considered for many types of 'clean' surgery. This can now be made both more straightforward and cost-effective by employing the oral route of administration.
authors.affiliation: Department of Surgery, Southampton University Hospitals, Hampshire, UK.
authors.forename: C J
authors.initials: CJ
authors.lastname: Ranaboldo
authors.forename: S E
authors.initials: SE
authors.lastname: Karran
authors.forename: I S
authors.initials: IS
authors.lastname: Bailey
authors.forename: S J
authors.initials: SJ
authors.lastname: Karran
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D003362:Cost-Benefit Analysis; D059685:Herniorrhaphy; D006801:Humans; D011183:Postoperative Complications / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents