Medication delivery in the short-bowel syndrome.
Technologic advances such as total parenteral nutrition have prolonged the lives of individuals with short-bowel syndrome who previously would not have survived. However, the day-to-day management of these patients presents a significant challenge to those who take care of them. Providing medications on either an acute or chronic basis without the use of their central catheters is a difficult clinical problem. This article reviews the approach and methods of treating short-bowel patients on the basis of their individual circumstances and physiology.
McFadden
M A
MA
Division of Gastroenterology and Nutrition, Medical College of Virginia, Richmond.
DeLegge
M H
MH
Kirby
D F
DF
D000042:Absorption; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002408:Catheters, Indwelling; D004333:Drug Administration Routes; D006801:Humans; D010289:Parenteral Nutrition, Total; D012778:Short Bowel Syndrome / Q000378:metabolism / Q000628:therapy*
D000900:Anti-Bacterial Agents