title: Radical hysterectomy for invasive cervical cancer. A 25-year prospective experience with the Miami technique.
abstract: BACKGROUND
  The Miami modification of the traditional Wertheim-Meigs radical hysterectomy was used to treat Stage IB-IIA cervical cancer in a 25-year prospective study involving 978 patients.
  
  
  METHODS
  The modifications included: vaginal reconstruction and closure using bladder and rectosigmoid serosa, retroperitoneal drainage through abdominal suction catheters, and suspension of the denuded ureters with the ipsilateral obliterated hypogastric artery.
  
  
  RESULTS
  The overall corrected 5-year survival rate was 90.1%, with a surgical mortality rate of 1.4% and an overall urinary fistula rate of 1.4%. This fistula rate was significantly better than a 4.4% incidence rate in a literature survey. Although not measured, the Miami modification appeared to lengthen the vagina.
  
  
  CONCLUSIONS
  Therefore, it was concluded that radical hysterectomy with the Miami modifications can be done safely in most patients with Stage IB-IIA cervical cancer.
authors.affiliation: Department of Obstetrics and Gynecology, University of Miami School of Medicine, FL 33136.
authors.forename: H E
authors.initials: HE
authors.lastname: Averette
authors.forename: H N
authors.initials: HN
authors.lastname: Nguyen
authors.forename: D M
authors.initials: DM
authors.lastname: Donato
authors.forename: M A
authors.initials: MA
authors.lastname: Penalver
authors.forename: B U
authors.initials: BU
authors.lastname: Sevin
authors.forename: R
authors.initials: R
authors.lastname: Estape
authors.forename: W A
authors.initials: WA
authors.lastname: Little
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000556:secondary / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D010298:Parity; D010388:Pelvis; D011446:Prospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D014599:Uterus / Q000601:surgery; D014621:Vagina / Q000601:surgery