title: Chronic fatigue syndrome: influence of histamine, hormones and electrolytes.
abstract: The chronic fatigue syndrome is poorly understood. We believe the underlying causes in many atopics and women are a persistent infection and hypersensitivity to the immune-suppressive effects of histamine and certain pathogens. We believe much to the symptomatology can be explained by all four types of hypersensitivity (Gell and Coombs classification) in reaction to a pathogen, electrolyte disturbances which include sometimes permanent changes in cell membranes' ability to pass electrolytes, sometimes permanent biochemical changes in mitochondrial function, and disturbances of insulin and T3-thyroid hormone functions. We also explain in detail what 'fatigue' means for these patients. We present evidence from the medical literature for the plausibility of our hypotheses.
authors.affiliation: Fitchburg State College, Fitchburg, Massachusetts 01420.
authors.forename: L
authors.initials: L
authors.lastname: Dechene
mesh_terms: D004573:Electrolytes / Q000378:metabolism; D015673:Fatigue Syndrome, Chronic / Q000209:etiology*; D005260:Female; D006632:Histamine / Q000276:immunology; D006728:Hormones / Q000378:metabolism; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D008297:Male; D008954:Models, Biological; D012727:Sex Characteristics
chemical_list: D004573:Electrolytes; D006728:Hormones; D006632:Histamine