title: Tail chasing in a bull terrier.
abstract: A Bull Terrier that was continuously chasing its tail was examined clinically, electroencephalographically, and by computed tomography of the head. The dog was also given test treatments with an anticonvulsant (diazepam) and a pure opioid antagonist (naloxone). The dog appeared to be hysterical and dissociated from its surroundings. Electroencephalography revealed a seizure pattern that was most marked over the temporal lobe, and computed tomography revealed mild hydrocephalus. Diazepam effectively controlled tail chasing, whereas naloxone did not. The dog was discharged on anticonvulsant therapy but subsequently had to be euthanatized when aggression developed. Results of examination and treatment have led the investigators to propose a hereditary mechanism for tail chasing, perhaps related to zinc malabsorption.
authors.affiliation: Section of Anesthesia and Behavioral Pharmacology, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536.
authors.forename: N H
authors.initials: NH
authors.lastname: Dodman
authors.forename: R
authors.initials: R
authors.lastname: Bronson
authors.forename: J
authors.initials: J
authors.lastname: Gliatto
mesh_terms: D000374:Aggression; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D003975:Diazepam / Q000494:pharmacology / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D004285:Dogs; D004569:Electroencephalography / Q000662:veterinary; D004833:Epilepsy, Temporal Lobe / Q000150:complications / Q000188:drug therapy / Q000662:veterinary*; D006849:Hydrocephalus / Q000473:pathology / Q000662:veterinary; D008297:Male; D009270:Naloxone / Q000494:pharmacology / Q000627:therapeutic use; D010634:Phenobarbital / Q000494:pharmacology / Q000627:therapeutic use; D013239:Stereotyped Behavior / Q000187:drug effects
chemical_list: D009270:Naloxone; D003975:Diazepam; D010634:Phenobarbital