title: Approaches to the management of cholelithiasis for the medical consultant.
abstract: Gallstones constitute a major medical problem in the United States. Patients who are asymptomatic require no therapy. Subsequent symptoms develop in a minority of patients, and the need for cholecystectomy is low. Symptomatic patients with reversible risk factors for gallstones, those who refuse surgery, and those who are poor surgical candidates should be considered for medical therapy. Our approach is outlined in Figure 2. Practical options include oral dissolution agents, contact dissolution agents, and shock-wave lithotripsy. Unfortunately, these therapies are successful in very select patients, and only a small percentage of patients with symptomatic gallstones will be candidates for any combination of these. If successful, the recurrence rate is high. Cholecystectomy is a safe, effective procedure that definitively treats symptomatic cholelithiasis. Patients with frequent symptoms of biliary colic, those with severe symptoms, and those who are young and do not have reversible risk factors for gallstones should be considered for cholecystectomy. If surgical expertise is available, the patient requiring an elective cholecystectomy should be educated regarding the laparoscopic approach that offers a better cosmetic result, shorter hospital stay, and faster return to normal activities. The medical consult must be aware of all the options available for managing patients with cholelithiasis. This will afford greater versatility in medical care or perioperative management.
authors.affiliation: Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Goldschmid
authors.forename: P G
authors.initials: PG
authors.lastname: Brady
mesh_terms: D001647:Bile Acids and Salts / Q000627:therapeutic use; D002763:Cholecystectomy; D002769:Cholelithiasis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008096:Lithotripsy; D012017:Referral and Consultation; D012307:Risk Factors
chemical_list: D001647:Bile Acids and Salts