title: Ulcerating necrobiosis lipoidica effectively treated with pentoxifylline.
abstract: A 30-year-old man had suffered from persistent ulceration within an area of necrobiosis lipoidica diabeticorum for 13 months. The ulcerating necrobiosis lipoidica was resistant to topical therapy and oral therapy with acetylsalicylic acid. However, the ulcers healed completely within 8 weeks of administration of 400 mg pentoxifylline twice daily.
authors.affiliation: Department of Dermatology, Academic Hospital Leiden, The Netherlands.
authors.forename: K C
authors.initials: KC
authors.lastname: Noz
authors.forename: M J
authors.initials: MJ
authors.lastname: Korstanje
authors.forename: B J
authors.initials: BJ
authors.lastname: Vermeer
mesh_terms: D000284:Administration, Oral; D000328:Adult; D006801:Humans; D008297:Male; D009335:Necrobiosis Lipoidica / Q000188:drug therapy*; D010431:Pentoxifylline / Q000008:administration & dosage / Q000627:therapeutic use*; D012883:Skin Ulcer / Q000188:drug therapy
chemical_list: D010431:Pentoxifylline