title: Ten-year experience with artificial pneumoperitoneum for end-stage, drug-resistant pulmonary tuberculosis.
abstract: Artificial pneumoperitoneum is a form of collapse therapy that was used in the treatment of cavitary pulmonary tuberculosis before the availability of antimycobacterial chemotherapy. We report a series of cases of far-advanced pulmonary disease due to multiple-drug-resistant Mycobacterium tuberculosis, wherein artificial pneumoperitoneum with or without subsequent surgical extirpation was used as an adjunct to chemotherapy. Overall, among these desperate cases, therapeutic pneumoperitoneum provided no clear benefit.
authors.affiliation: Division of Infectious Diseases, University of Colorado Health Sciences Center, Denver.
authors.forename: A T
authors.initials: AT
authors.lastname: Nitta
authors.forename: M D
authors.initials: MD
authors.lastname: Iseman
authors.forename: J D
authors.initials: JD
authors.lastname: Newell
authors.forename: L A
authors.initials: LA
authors.lastname: Madsen
authors.forename: M
authors.initials: M
authors.lastname: Goble
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004352:Drug Resistance, Microbial; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011028:Pneumoperitoneum, Artificial / Q000009:adverse effects; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000995:Antitubercular Agents