Radioimmunoguided surgery for colorectal cancer.
This article provides a basic understanding of the RIGS (radioimmunoguided surgery) technique and reviews the evolution of the technology from its inception as an experimental technique in animal models to the current clinical trials in patients. A review of published data from the laboratory and from preclinical and clinical trials is updated by a statement of the current status of RIGS. A look at the future of RIGS as an experimental and clinical tool highlights current areas of investigation based on this technology.
Kim
J A
JA
Ohio State University Hospitals.
Triozzi
P L
PL
Martin
E W
EW
D000818:Animals; D000951:Antigens, Neoplasm; D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D004195:Disease Models, Animal; D005544:Forecasting; D006023:Glycoproteins; D006801:Humans; D008207:Lymphatic Metastasis; D051379:Mice; D009077:Mucins / Q000302:isolation & purification; D015337:Multicenter Studies as Topic; D016719:Radioimmunodetection / Q000379:methods* / Q000639:trends; D015996:Survival Rate
D000951:Antigens, Neoplasm; D006023:Glycoproteins; D009077:Mucins; C047052:tumor-associated antigen 72