A review of gene transfer techniques.
The ability to transfer genetic material from one cell to another provides a novel approach for the investigation and potential treatment of a variety of diseases. Several gene transfer techniques have been developed. Of these, the use of retroviruses as vectors has allowed highly efficient and stable introduction of foreign genes into target mammalian cells, thus making gene therapy possible. The current prospects are that some unusual lethal diseases can be corrected and that various forms of cancer will be treated in this manner.
Watt
P C
PC
Department of Surgery, UCLA School of Medicine.
Sawicki
M P
MP
Passaro
E
E
D000818:Animals; D002477:Cells; D005822:Genetic Vectors; D006801:Humans; D008322:Mammals; D012190:Retroviridae; D014162:Transfection / Q000379:methods*