title: Nonsteroidal anti-inflammatory drugs. Tailoring therapy to achieve results and avoid toxicity.
abstract: When used appropriately, non-steroidal anti-inflammatory drugs (NSAIDs) are safe and effective for treating pain and inflammation. NSAIDs that block both the lipoxygenase and cyclooxygenase pathways may be advantageous in some patients. New classes of NSAIDs that may have a more favorable safety profile than older agents may improve patient outcome. However, all patients receiving NSAIDs, especially the elderly, should be carefully monitored for possible drug-related complications.
authors.affiliation: Jefferson Medical College, Thomas Jefferson University, Department of Family Medicine, Philadelphia, PA 19107.
authors.forename: P
authors.initials: P
authors.lastname: Amadio
authors.forename: D M
authors.initials: DM
authors.lastname: Cummings
authors.forename: P
authors.initials: P
authors.lastname: Amadio
mesh_terms: D000042:Absorption; D000367:Age Factors; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D001927:Brain Diseases / Q000139:chemically induced; D004066:Digestive System Diseases / Q000139:chemically induced; D004347:Drug Interactions; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D008171:Lung Diseases / Q000139:chemically induced; D010146:Pain / Q000188:drug therapy; D012307:Risk Factors; D013997:Time Factors; D014652:Vascular Diseases / Q000139:chemically induced
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal