Unilateral frontal lobectomy can produce strategy application disorder.
Following a 5 cm left frontal lobectomy for the removal of a mixed astrocytoma-oligodendroglioma, a 51 year old right handed man showed a marked dissociation between his performance on standard neuropsychological tests and his everyday behaviour. In contrast to his intact neuropsychological test performance, he was impaired on a test of "strategy application" which requires goal articulation, plan specification, self-monitoring, and evaluation of outcomes, as well as the establishment of mental "markers" to trigger specific behaviour. Strategy application disorder can therefore be produced by a unilateral circumscribed frontal lobe lesions.
Goldstein
L H
LH
Neuropsychiatry Unit, Maudsley Hospital, London.
Bernard
S
S
Fenwick
P B
PB
Burgess
P W
PW
McNeil
J
J
D000786:Anger / Q000502:physiology; D001254:Astrocytoma / Q000601:surgery*; D001364:Awareness / Q000502:physiology; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000503:physiopathology*; D001932:Brain Neoplasms / Q000601:surgery*; D003657:Decision Making / Q000502:physiology; D005625:Frontal Lobe / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000175:diagnosis / Q000503:physiopathology*; D009483:Neuropsychological Tests; D009837:Oligodendroglioma / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology*; D011340:Problem Solving / Q000502:physiology*; D011612:Psychosurgery; D012919:Social Behavior