title: Leuprolide acetate and bone mineral density measured by quantitative digitized radiography.
abstract: Quantitative digitized radiography uses low-energy photons to measure bone density with precision not available in older techniques. Using this method, lumbar spine density was evaluated in 12 women before and after 6 months of therapy with LA. A 2.9% decrement in mean bone density was documented. The reproducibility of quantitative digitized radiography suggests that this small degree of bone mineral loss is a real phenomenon and not an artifact of measurement. The clinical significance of this degree of bone mineral loss has yet to be established.
authors.affiliation: Department of Obstetrics and Gynecology, Georgetown University Medical Center, Washington, D.C. 20007-2197.
authors.forename: A R
authors.initials: AR
authors.lastname: Scialli
authors.forename: K J
authors.initials: KJ
authors.lastname: Jestila
authors.forename: J A
authors.initials: JA
authors.lastname: Simon
mesh_terms: D000293:Adolescent; D000328:Adult; D015519:Bone Density / Q000187:drug effects*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D016729:Leuprolide / Q000494:pharmacology*; D008875:Middle Aged; D011856:Radiographic Image Enhancement
chemical_list: D016729:Leuprolide