title: Audiological assessment of eleven congenital hypothyroid infants before and after treatment.
abstract: Eleven congenital hypothyroid newborns were consecutively referred for audiological evaluation before any treatment. Evoked otoacoustic emissions were present bilaterally in 9 newborns. These results suggest the normality outer hair cells and contrast with results obtained in experimental studies. The auditory brainstem responses in 6 newborns showed a prolonged wave I, as previously reported by other authors. At 9 to 12 months of age, all children treated had evoked otoacoustic emissions in at least one ear. In 9 cases, the auditory threshold was normal (equal to or below 20 dB) as determined by behavioural tests.
authors.affiliation: ORL Department, Hôpital Robert Debré, Faculty Bichat, University Paris VII, France.
authors.forename: M
authors.initials: M
authors.lastname: François
authors.forename: P
authors.initials: P
authors.lastname: Bonfils
authors.forename: J
authors.initials: J
authors.lastname: Leger
authors.forename: P
authors.initials: P
authors.lastname: Avan
authors.forename: P
authors.initials: P
authors.lastname: Czernichow
authors.forename: P
authors.initials: P
authors.lastname: Narcy
mesh_terms: D001309:Auditory Threshold; D003051:Cochlea / Q000503:physiopathology*; D003214:Conditioning, Classical; D003409:Congenital Hypothyroidism; D003638:Deafness / Q000151:congenital / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem; D005500:Follow-Up Studies; D006320:Hearing Tests; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy; D007231:Infant, Newborn; D008297:Male; D009949:Orientation; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D013974:Thyroxine