title: Southernmost carriers of HTLV-I/II in the world.
abstract: To clarify the real distribution of HTLV-I and -II carriers among indigenous people in central and South America, blood samples collected from indigenous people in isolated regions of Southern Chile were examined. Among 199 inhabitants from Chiloe Island and Pitrufquen town, three cases (1.5%) showed positive anti-HTLV-I antibodies. Two out of the three (82-year-old male and 58-year-old female) reacted to HTLV-II-specific Gag and/or Env proteins but not to HTLV-I-specific ones. The latter case was confirmed as an HTLV-II carrier by polymerase chain reaction test.
authors.affiliation: Department of Neurology, Faculty of Medicine, University of Chile, Santiago.
authors.forename: L
authors.initials: L
authors.lastname: Cartier
authors.forename: F
authors.initials: F
authors.lastname: Araya
authors.forename: J L
authors.initials: JL
authors.lastname: Castillo
authors.forename: V
authors.initials: V
authors.lastname: Zaninovic
authors.forename: M
authors.initials: M
authors.lastname: Hayami
authors.forename: T
authors.initials: T
authors.lastname: Miura
authors.forename: J
authors.initials: J
authors.lastname: Imai
authors.forename: S
authors.initials: S
authors.lastname: Sonoda
authors.forename: H
authors.initials: H
authors.lastname: Shiraki
authors.forename: K
authors.initials: K
authors.lastname: Miyamoto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001483:Base Sequence; D002353:Carrier State / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D002677:Chile / Q000453:epidemiology; D004279:DNA, Viral / Q000097:blood / Q000235:genetics; D005260:Female; D015481:HTLV-I Antibodies / Q000097:blood; D015490:HTLV-I Infections / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D015491:HTLV-II Infections / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D015367:Human T-lymphotropic virus 2 / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides; D016133:Polymerase Chain Reaction / Q000379:methods; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D004279:DNA, Viral; D015481:HTLV-I Antibodies; D009838:Oligodeoxyribonucleotides