title: Relationships between change in aerobic fitness and changes in blood pressure and plasma lipids in men and women: the "Adelaide 1000" 4-year follow up.
abstract: The aim was to assess relationships between increased aerobic fitness sustained over 4 years, and changes in blood pressure (SBP and DBP) and lipids. Measurements were made of BP, lipids, weight, and fitness in 1000 middle-aged men and women entering a fitness programme, and were repeated 2 and 4 years later. The 342 men and women selected for this 4-year follow-up were either consistent fitness "gainers" (improved by > 5%) or "non-gainers" (improved by < or = 5%) at 2 and 4 year stages. For men, comparisons of these groups and multiple regression analyses failed to show significant relationships between changes in fitness and risk factors over the 4 year period. For women, "gainers" improved more than "non-gainers" in SBP (by 4 mmHg, p < 0.03), HDL/cholesterol ratio (by 0.01 mmol l-1, p < 0.0001), and triglycerides (by 0.02 mmol l-1, p < 0.05); regression analyses resulted in a significant relationship between changes in fitness and SBP (B = 0.012, p < 0.05). The study gave weak support to the existence of causal relationships between aerobic fitness and CHD risk factors for women, and no support for men.
authors.affiliation: Institute for Fitness Research and Training, University of Adelaide, South Australia.
authors.forename: A W
authors.initials: AW
authors.lastname: Sedgwick
authors.forename: D W
authors.initials: DW
authors.lastname: Thomas
authors.forename: M
authors.initials: M
authors.lastname: Davies
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001794:Blood Pressure / Q000502:physiology*; D001835:Body Weight / Q000502:physiology; D003327:Coronary Disease / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010809:Physical Fitness / Q000502:physiology*; D012044:Regression Analysis; D012146:Rest / Q000502:physiology; D012307:Risk Factors; D013997:Time Factors
chemical_list: D008055:Lipids