An extended genetic linkage map and an "index" map for human chromosome 17.
Our previous genetic map for chromosome 17 has been expanded to include 72 loci defined by 90 RFLP markers and four microsatellite markers assayed by the polymerase chain reaction. Forty-one of these loci were ordered with odds greater than 1000:1 against local inversion, and the other 31 were ordered within 95% confidence limits. From the set of 41 unambiguously mapped loci, 14 well-spaced "index markers" can be extracted for efficient genetic studies. The complete map spans 173 cM (136 cM in males and 214 cM in females); average spacing between markers is 4.2 cM.
O'Connell
P
P
Howard Hughes Medical Institute, University of Utah, Salt Lake City 84112.
Plaetke
R
R
Matsunami
N
N
Odelberg
S
S
Jorde
L
L
Chance
P
P
Leppert
M
M
Lalouel
J M
JM
White
R
R
D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D004247:DNA; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D008297:Male; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D051381:Rats; D011995:Recombination, Genetic; D012727:Sex Characteristics
D005819:Genetic Markers; D004247:DNA