title: Urinary excretion of immunoglobulins and their subunits in human subjects before and after exercise.
abstract: Immunoglobulins and their subunits in urines collected before and after exercise from healthy human subjects were studied. Quantitative analysis showed that only gamma A- and gamma G-immunoglobulins were excreted as whole molecules in normal urine, at a concentration of 0.35 and 1.70 micrograms/min., respectively. Exercise enhanced the excretion of both types of molecules. In some cases, gamma D-immunoglobulins were found in "exercise urine." Gel filtration on Sephadex G-150 showed that only gamma G-subunits were present in normal and in "exercise urine." The distribution of gamma G-subunits was not affected by exercise. The authors consider the importance of the present data in relation to renal physiology.
authors.affiliation: Laboratoire de l'Effort, Université Libre de Bruxelles, Belgium.
authors.forename: J R
authors.initials: JR
authors.lastname: Poortmans
authors.forename: R W
authors.initials: RW
authors.lastname: Jeanloz
mesh_terms: D015444:Exercise / Q000502:physiology*; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000652:urine; D007141:Immunoglobulin Fc Fragments / Q000652:urine; D007137:Immunoglobulin alpha-Chains / Q000652:urine; D007138:Immunoglobulin delta-Chains / Q000652:urine; D007142:Immunoglobulin gamma-Chains / Q000652:urine; D007136:Immunoglobulins / Q000652:urine*; D008297:Male
chemical_list: D007140:Immunoglobulin Fab Fragments; D007141:Immunoglobulin Fc Fragments; D007137:Immunoglobulin alpha-Chains; D007138:Immunoglobulin delta-Chains; D007142:Immunoglobulin gamma-Chains; D007136:Immunoglobulins