Osteogenesis imperfecta and hyperplastic callus formation: light- and electron-microscopic findings.
In rare cases of osteogenesis imperfecta, an "overshoot" growth of new bone may occur, which, clinically gives the impression of a tumour. This condition is known as hyperplastic callus formation. Morphology showed an excessive mixed desmal-chondral osteoneogenesis. Atypical collagen fibrils in non-callus tissue represent an indicator for this callus formation in individual patients.
Stöss
H
H
Department of Pathology, University of Erlangen, Germany.
Pontz
B
B
Vetter
U
U
Karbowski
A
A
Brenner
R
R
Spranger
J
J
D002146:Bony Callus / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D008854:Microscopy, Electron; D010013:Osteogenesis Imperfecta / Q000150:complications / Q000473:pathology*