Bone scan findings in craniometaphyseal dysplasia.
Craniometaphyseal dysplasia is a rare genetic bone disorder characterized by undertubulation of the long bones, especially in the lower extremities, and sclerosis of the skull base. Differentiation from other sclerosing bone dysplasias, including metaphyseal dysplasia (Pyle's disease), craniodiaphyseal dysplasia, and diaphyseal dysplasia is based largely on characteristic radiographic findings. Radionuclide bone scans usually are not necessary for diagnosis, but are helpful in demonstrating the abnormal bone metabolism. The authors report the first whole-body bone images in a patient with craniometaphyseal dysplasia, demonstrating the abnormal bone activity over time.
Ramseyer
L T
LT
Department of Radiological Sciences, University of Oklahoma Health Sciences Center, Oklahoma City 73190.
Leonard
J C
JC
Stacy
T M
TM
D001848:Bone Diseases, Developmental / Q000000981:diagnostic imaging* / Q000235:genetics; D002648:Child; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011877:Radionuclide Imaging; D012886:Skull / Q000002:abnormalities* / Q000000981:diagnostic imaging; D013669:Technetium Tc 99m Medronate
D013669:Technetium Tc 99m Medronate