title: Translocation (X;1) in papillary renal cell carcinoma. A new cytogenetic subtype.
abstract: We report a consistent t(X;1)(p11.2;q21) that was observed in four cases of papillary renal tumors. In one of the cases, two cells showed the cytogenetic abnormality as the only change, whereas the other cases showed additional chromosomal anomalies particularly involving chromosomes 7 and 17. One identical t(X;1) has been reported previously in a papillary renal cell carcinoma. To date, all of the patients carrying this translocation have been males.
authors.affiliation: Southwest Biomedical Research Institute and Genetrix, Inc., Scottsdale, Arizona 85251.
authors.forename: A M
authors.initials: AM
authors.lastname: Meloni
authors.forename: R M
authors.initials: RM
authors.lastname: Dobbs
authors.forename: J E
authors.initials: JE
authors.lastname: Pontes
authors.forename: A A
authors.initials: AA
authors.lastname: Sandberg
mesh_terms: D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000235:genetics* / Q000473:pathology; D002292:Carcinoma, Renal Cell / Q000235:genetics* / Q000473:pathology; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D006801:Humans; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014178:Translocation, Genetic; D014960:X Chromosome