title: Generation of cytotoxic agents by targeted enzymes.
authors.affiliation: Bristol-Myers Squibb Pharmaceutical Research Institute, Seattle, Washington 98121.
authors.forename: P D
authors.initials: PD
authors.lastname: Senter
authors.forename: P M
authors.initials: PM
authors.lastname: Wallace
authors.forename: H P
authors.initials: HP
authors.lastname: Svensson
authors.forename: V M
authors.initials: VM
authors.lastname: Vrudhula
authors.forename: D E
authors.initials: DE
authors.lastname: Kerr
authors.forename: I
authors.initials: I
authors.lastname: Hellström
authors.forename: K E
authors.initials: KE
authors.lastname: Hellström
mesh_terms: D000469:Alkaline Phosphatase / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents / Q000378:metabolism* / Q000627:therapeutic use; D004337:Drug Carriers; D057487:Enzyme Therapy; D004798:Enzymes / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D011355:Prodrugs / Q000378:metabolism* / Q000627:therapeutic use; D011623:gamma-Glutamyl Hydrolase / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use
chemical_list: D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D004337:Drug Carriers; D004798:Enzymes; D011355:Prodrugs; D000469:Alkaline Phosphatase; D011623:gamma-Glutamyl Hydrolase