title: Neurocardiogenic syncope. Diagnosis, mechanisms, and treatment.
abstract: Neurocardiogenic syncope is a common medical problem that can be identified easily by history and the findings of the head-up tilt test. Depressor reflexes from the heart causing sympathetic withdrawal that, in turn, lead to peripheral vasodilatation and hypotension may have an important role in the pathogenesis of neurocardiogenic dysfunction. Once a diagnosis of neurocardiogenic syncope has been made, specific therapeutic strategies can usually prevent recurrent syncope. However, the natural history of neurocardiogenic syncope has not been studied. Double-blind placebo-controlled studies or drug withdrawal trials are needed to assess whether all patients with neurocardiogenic syncope need lifelong therapy.
authors.affiliation: Sinai Samaritan Medical Center, Milwaukee, Wisconsin.
authors.forename: J S
authors.initials: JS
authors.lastname: Sra
authors.forename: M R
authors.initials: MR
authors.lastname: Jazayeri
authors.forename: A
authors.initials: A
authors.lastname: Dhala
authors.forename: S
authors.initials: S
authors.lastname: Deshpande
authors.forename: Z
authors.initials: Z
authors.lastname: Blanck
authors.forename: M
authors.initials: M
authors.lastname: Akhtar
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology; D002319:Cardiovascular System / Q000294:innervation; D006801:Humans; D013575:Syncope / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy