Pathophysiology of muscular dystrophy.
The inevitable and remorseless clinical decline in a patient with Duchenne muscular dystrophy (DMD) evokes a special sense of impotent desperation, which was, until recently, exacerbated by lack of obvious progress in its treatment. However, identification of the culpable gene has provided insight into the pathogenesis of DMD and glimmerings of hope for its treatment.
Partridge
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Department of Histopathology, Charing Cross and Westminster Medical School, London.
D000595:Amino Acid Sequence; D000818:Animals; D002415:Cats; D004195:Disease Models, Animal; D004285:Dogs; D016189:Dystrophin / Q000172:deficiency / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009136:Muscular Dystrophies / Q000235:genetics / Q000503:physiopathology*; D009137:Muscular Dystrophy, Animal
D016189:Dystrophin