Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13.
S-lac lectins are a family of soluble lactose-binding proteins thought to function in the control of cell growth. We now report the chromosomal mapping of two members of the family, termed L-14-I and L-14-II, to the q12-q13 region of human chromosome 22, suggesting the possibility of a cluster of genes for lactose-binding proteins.
Mehrabian
M
M
Division of Cardiology, University of California, Los Angeles 90024.
Gitt
M A
MA
Sparkes
R S
RS
Leffler
H
H
Barondes
S H
SH
Lusis
A J
AJ
D000818:Animals; D002352:Carrier Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D002892:Chromosomes, Human, Pair 22; D029968:Escherichia coli Proteins; D006801:Humans; D006822:Hybrid Cells; D017403:In Situ Hybridization; D007785:Lactose / Q000378:metabolism*; D037102:Lectins / Q000235:genetics*; D051379:Mice; D009004:Monosaccharide Transport Proteins; D005810:Multigene Family; D027981:Symporters
D002352:Carrier Proteins; D029968:Escherichia coli Proteins; C050221:LacY protein, E coli; D037102:Lectins; D009004:Monosaccharide Transport Proteins; D027981:Symporters; D007785:Lactose