Selective screen to recover pairs of deletion-tandem duplications.
A method of selecting pairs of deletion-tandem duplications in an autosome arm of Drosophila has been developed. Males containing autosome 2 and the right and left free arms of this autosome produce gametes with the metacentric and the free arm through meiotic non-disjunction. Unequal exchanges induced in such gametes give deletions and tandem duplications within the left or right chromosomal arms. This approach removes the necessity of using markers to identify deletions in the chromosome region.
Omelyanchuk
L
L
Institute of Cytology and Genetics, Novosibirsk, Russia.
D000818:Animals; D002872:Chromosome Deletion; D003433:Crosses, Genetic; D004330:Drosophila / Q000235:genetics*; D005260:Female; D015321:Gene Rearrangement; D008297:Male