title: Accuracy and reproducibility of duplex ultrasonography in grading femoropopliteal stenoses.
abstract: OBJECTIVE
  The aim of this study was to determine the accuracy of Doppler waveform characteristics in grading femoropopliteal stenoses and to determine the interobserver and intraobserver reproducibility of measuring the same waveform characteristics.
  
  
  METHODS
  Thirty patients with isolated areas of stenosis found by arteriography were evaluated by color duplex sonography. Each patient underwent scanning by two observers on two separate occasions. Each observer was blind to the other's results. Doppler spectra were recorded in areas where color change suggested the highest velocity and also at the nearest normal proximal area. Peak systolic velocity, spectral broadening, and waveform configuration were measured at each site.
  
  
  RESULTS
  An increase in peak systolic velocity of more than 200% accurately predicted a 50% or greater reduction in luminal diameter on angiography (70% sensitivity, 96% specificity). The presence of spectral broadening and an abnormal waveform shape were found to correlate poorly with the degree of stenosis. Analysis of variance showed no significant difference between observers in velocity measurements (p = 0.78).
  
  
  CONCLUSIONS
  We conclude that although stenoses of greater than 50% can be distinguished from minor stenoses, more precise definition of the degree of narrowing is unlikely. The good repeatability of the velocity ratio makes it an excellent tool for monitoring major changes in the progression of disease.
authors.affiliation: Department of Public Health Sciences, University of Edinburgh, United Kingdom.
authors.forename: G C
authors.initials: GC
authors.lastname: Leng
authors.forename: M R
authors.initials: MR
authors.lastname: Whyman
authors.forename: P T
authors.initials: PT
authors.lastname: Donnan
authors.forename: C V
authors.initials: CV
authors.lastname: Ruckley
authors.forename: I
authors.initials: I
authors.lastname: Gillespie
authors.forename: F G
authors.initials: FG
authors.lastname: Fowkes
authors.forename: P L
authors.initials: PL
authors.lastname: Allan
mesh_terms: D000704:Analysis of Variance; D003251:Constriction, Pathologic / Q000145:classification / Q000000981:diagnostic imaging; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D006801:Humans; D015588:Observer Variation; D011150:Popliteal Artery / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011859:Radiography; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D014463:Ultrasonography