title: Characteristics of Escherichia coli isolated from septic foals.
abstract: Fifteen Escherichia coli isolates from the blood and tissue of foals with septicemia were compared with 15 from the feces of clinically normal horses. Comparisons were made with respect to survival in normal equine serum, production of aerobactin, and production of hemolysin. Isolates from the blood and tissues of septic foals were more likely to be resistant to equine serum than were isolates from feces of clinically normal horses. There were minimal differences between the isolates with respect to aerobactin and hemolysin production, almost all being nonhemolytic and aerobactin negative. Serum resistance is probably a virulence determinant for invasive E. coli in horses.
authors.affiliation: Department of Veterinary Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis 95616.
authors.forename: D C
authors.initials: DC
authors.lastname: Hirsh
authors.forename: C
authors.initials: C
authors.lastname: Kirkham
authors.forename: W D
authors.initials: WD
authors.lastname: Wilson
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D016470:Bacteremia / Q000382:microbiology / Q000662:veterinary*; D001770:Blood Bactericidal Activity; D004926:Escherichia coli / Q000276:immunology / Q000502:physiology*; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D005243:Feces / Q000382:microbiology; D006461:Hemolysis; D006734:Horse Diseases / Q000382:microbiology*; D006736:Horses; D006801:Humans; D006877:Hydroxamic Acids / Q000378:metabolism; D017262:Siderophores / Q000096:biosynthesis
chemical_list: D006877:Hydroxamic Acids; D017262:Siderophores; C031819:aerobactin