Rapamycin reverses acute heart, kidney, and pancreas allograft rejection and prevents accelerated heart allograft rejection in the rat.
Chen
H
H
Laboratory of Experimental Surgery, Notre-Dame Hospital, University of Montreal, Quebec, Canada.
Wu
J
J
Xu
D
D
Luo
H
H
Daloze
P
P
D000208:Acute Disease; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D004386:Duodenum / Q000637:transplantation; D006084:Graft Rejection / Q000188:drug therapy* / Q000517:prevention & control; D016027:Heart Transplantation / Q000276:immunology*; D007074:Immunoglobulin G / Q000097:blood; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D016035:Pancreas Transplantation / Q000276:immunology*; D011090:Polyenes / Q000627:therapeutic use*; D051381:Rats; D011915:Rats, Inbred BUF; D011917:Rats, Inbred Lew; D011920:Rats, Inbred WF; D020123:Sirolimus; D014184:Transplantation, Homologous
D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D011090:Polyenes; D020123:Sirolimus