title: Avian epidermis contains ATPase- and Ia-positive Langerhans-like cells.
abstract: The occurrence of cells resembling mammalian Langerhans cells in the avian epidermis was studied by ATPase histochemistry, Ia immunoreactivity and electron microscopy. The existence of MHC class II antigen-(Ia) expressing, ATPase-positive dendritic cells, which are ultrastructurally similar to mammalian Langerhans cells except for the absence of Birbeck granules, was demonstrated. These cells may be a basic component of the immune system of birds.
authors.affiliation: Department of Anatomy, Nagoya University School of Medicine, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Akhter
authors.forename: M
authors.initials: M
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Hoshino
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001717:Birds / Q000033:anatomy & histology* / Q000276:immunology / Q000378:metabolism; D002645:Chickens; D003713:Dendritic Cells / Q000201:enzymology / Q000276:immunology / Q000648:ultrastructure; D005260:Female; D000949:Histocompatibility Antigens Class II; D006651:Histocytochemistry; D007150:Immunohistochemistry; D007801:Langerhans Cells / Q000201:enzymology / Q000276:immunology / Q000648:ultrastructure*; D008297:Male; D008322:Mammals; D008854:Microscopy, Electron; D011784:Quail; D013045:Species Specificity
chemical_list: D000949:Histocompatibility Antigens Class II; D000251:Adenosine Triphosphatases