title: Surgery for Crohn's disease.
abstract: In the last 12 years, 72 operations have been performed on 41 patients for Crohn's disease in this hospital. The patients were predominantly young (mean age 32 yrs) and there were more females than males. 28 had ileocolic disease, three small intestinal, two pan-enteric and eight colonic. Pain (in 76%), diarrhoea (56%) and weight loss (66%) were the main presenting symptoms. Diarrhoea occurred in all those with colonic disease, but in only 43% of those with ileocolic disease. A right hemicolectomy (28 patients), colonic resection (12) and small intestinal resection (9) were the commonest operations. There were no deaths. 22 patients had a total of 26 complications after surgery, eight necessitating further surgery. The mean post-operative stay was 15 days, being lowest in those with ileocolic disease. 19 patients have required only one operation, with a mean follow-up of 5.3 years. These patients also had significantly less complications (p < 0.05). Half of the patients requiring surgery for Crohn's disease have done very well. The other half require many operations and have a substantial morbidity.
authors.affiliation: Dept of Pathology, University College Hospital, Galway.
authors.forename: M A
authors.initials: MA
authors.lastname: Stokes
authors.forename: K
authors.initials: K
authors.lastname: Barry
authors.forename: R
authors.initials: R
authors.lastname: Sullivan
authors.forename: J
authors.initials: J
authors.lastname: Byrne
authors.forename: J
authors.initials: J
authors.lastname: Callaghan
authors.forename: H F
authors.initials: HF
authors.lastname: Given
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003424:Crohn Disease / Q000453:epidemiology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007494:Ireland / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology; D011379:Prognosis