Audiological assessment of eleven congenital hypothyroid infants before and after treatment.
Eleven congenital hypothyroid newborns were consecutively referred for audiological evaluation before any treatment. Evoked otoacoustic emissions were present bilaterally in 9 newborns. These results suggest the normality outer hair cells and contrast with results obtained in experimental studies. The auditory brainstem responses in 6 newborns showed a prolonged wave I, as previously reported by other authors. At 9 to 12 months of age, all children treated had evoked otoacoustic emissions in at least one ear. In 9 cases, the auditory threshold was normal (equal to or below 20 dB) as determined by behavioural tests.
François
M
M
ORL Department, Hôpital Robert Debré, Faculty Bichat, University Paris VII, France.
Bonfils
P
P
Leger
J
J
Avan
P
P
Czernichow
P
P
Narcy
P
P
D001309:Auditory Threshold; D003051:Cochlea / Q000503:physiopathology*; D003214:Conditioning, Classical; D003409:Congenital Hypothyroidism; D003638:Deafness / Q000151:congenital / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem; D005500:Follow-Up Studies; D006320:Hearing Tests; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy; D007231:Infant, Newborn; D008297:Male; D009949:Orientation; D013974:Thyroxine / Q000627:therapeutic use
D013974:Thyroxine