The morquio A syndrome (mucopolysaccharidosis IVA) gene maps to 16q24.3.
The gene for N-acetylgalactosamine-6-sulfatase, the deficiency of which results in Morquio A syndrome (mucopolysaccharidosis type IVA), was assigned to chromosome 16 at band q24.3 by fluorescence in situ hybridization. Localization of this band was confirmed by PCR analysis of a somatic cell hybrid panel used for fine mapping of chromosome 16.
Baker
E
E
Department of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital, Australia.
Guo
X H
XH
Orsborn
A M
AM
Sutherland
G R
GR
Callen
D F
DF
Hopwood
J J
JJ
Morris
C P
CP
D000818:Animals; D001483:Base Sequence; D002811:Chondroitinsulfatases / Q000172:deficiency / Q000235:genetics*; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D004277:DNA, Single-Stranded; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D009085:Mucopolysaccharidosis IV / Q000235:genetics*; D016133:Polymerase Chain Reaction
D004277:DNA, Single-Stranded; D002811:Chondroitinsulfatases