Prediction of the migration behavior of organic acids in micellar electrokinetic chromatography.
The migration behavior of an homologous series of phenols in micellar electrokinetic chromatography is quantitatively presented. This model describes mobility in terms of fundamental physical and chemical constants of each solute (acid dissociation constant Ka, micelle binding constant Km), the pH of the buffer, and the micelle concentration ([M]) in the buffer. The model was used to predict the mobility of each solute over a two-dimensional pH/[M] space. Predicted and actual electropherograms show the usefulness of this technique.
Smith
S C
SC
Department of Chemistry, North Carolina State University, Raleigh 27695-8204.
Khaledi
M G
MG
D000143:Acids / Q000737:chemistry*; D002845:Chromatography / Q000379:methods*; D007700:Kinetics; D008823:Micelles; D008956:Models, Chemical
D000143:Acids; D008823:Micelles