[Idiopathic hypercalciuria--the effect of physical stress on calciuria].
The authors investigated calciuria (dU-Ca) in a group of 37 patients with confirmed idiopathic hypercalciuria. The group comprised 17 men, mean age 46.1 +/- 10.4 years, and 20 women, mean age 55.7 +/- 14.9 years (on statistical evaluation the group of women was significantly older, p > 0.01). After a load the calciuria declined in men by 27.3%, in women by 31.3%, in the total group by 27.85% (all reduced values are statistically significant as compared with controls, p < 0.001). In individual subjects calciuria declined by as much as 58%. Similar results were achieved during treatment with hydrochlorothiazide: the drop of calciuria during a physical load in men was 27.60%, in women 34.70%. The group of patients who participated in the whole programme, i.e. rest/load and rest/load after one month hydrochlorothiazide treatment, 25 mg/day, is too small for conclusive evaluation.


CONCLUSIONS
physical load and hydrochlorothiazide reduce the amount of calcium excreted in urine by patients with idiopathic hypercalciuria.
Kocián
J
J
Katedra interního lékarství, ILF, Praha.
D002118:Calcium / Q000652:urine*; D015444:Exercise; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged
D006852:Hydrochlorothiazide; D002118:Calcium