Inhibition of Escherichia coli chemotaxis by omega-conotoxin, a calcium ion channel blocker.
Escherichia coli chemotaxis was inhibited by omega-conotoxin, a calcium ion channel blocker. With Tris-EDTA-permeabilized cells, nanomolar levels of omega-conotoxin inhibited chemotaxis without loss of motility. Cells treated with omega-conotoxin swam with a smooth bias, i.e., tumbling was inhibited.
Tisa
L S
LS
Department of Biochemistry, University of Wisconsin-Madison 53706-1569.
Olivera
B M
BM
Adler
J
J
D002121:Calcium Channel Blockers / Q000494:pharmacology*; D002633:Chemotaxis / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects* / Q000502:physiology; D010456:Peptides, Cyclic / Q000494:pharmacology*; D020960:omega-Conotoxins
D002121:Calcium Channel Blockers; D010456:Peptides, Cyclic; D020960:omega-Conotoxins; C053423:Conus magus toxin