Chemically bonded stationary phases that use synthetic hosts containing aromatic binding clefts: HPLC analysis of nitro-substituted polycyclic aromatic hydrocarbons.
The synthesis of hosts with improved binding affinities for nitroaromatic guests is described. Association constants for several host-guest complexes were measured in chloroform solution and ranged over three orders of magnitude. Two hosts were covalently linked to silica gel to produce chemically bonded stationary phases for HPLC. The use of these phases for HPLC analysis of nitro-substituted polycyclic aromatic hydrocarbons is discussed.
Zimmerman
S C
SC
Department of Chemistry, University of Illinois, Urbana 61801.
Saionz
K W
KW
Zeng
Z
Z
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D015394:Molecular Structure; D009574:Nitro Compounds / Q000032:analysis* / Q000138:chemical synthesis / Q000737:chemistry; D011083:Polycyclic Compounds / Q000032:analysis* / Q000138:chemical synthesis / Q000737:chemistry; D013329:Structure-Activity Relationship
D007202:Indicators and Reagents; D009574:Nitro Compounds; D011083:Polycyclic Compounds