title: Enhanced MRI in patients with Ramsay-Hunt's syndrome.
abstract: Enhanced MRI was performed in 14 patients with Ramsay-Hunt's syndrome to investigate the pathogenesis of this syndrome. All MRI studies were performed on a 0.5T superconductivity MRI system using a head coil with Gd-DTPA. Enhancement was observed in the areas of the distal internal auditory canal and labyrinthine segment in many patients, and was especially prominent in patients suffering from vertigo, tinnitus, and hearing loss. In some patients it involved not only the facial nerve of the internal auditory canal but also the cochlear nerve and vestibular nerves. Since histological changes of the facial nerve in patients with Ramsay-Hunt's syndrome are assumed to occur in the distal internal auditory canal and labyrinthine segment, which is more proximal than the geniculate ganglion, and the possibility is suggested that inflammation may spread to the vestibular and cochlear nerve via the internal auditory canal.
authors.affiliation: Department of Otolaryngology, Kansai Medical University, Osaka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yanagida
authors.forename: K
authors.initials: K
authors.lastname: Ushiro
authors.forename: T
authors.initials: T
authors.lastname: Yamashita
authors.forename: T
authors.initials: T
authors.lastname: Kumazawa
authors.forename: T
authors.initials: T
authors.lastname: Katoh
mesh_terms: D000368:Aged; D003056:Cochlear Nerve / Q000503:physiopathology; D003287:Contrast Media; D005154:Facial Nerve / Q000503:physiopathology; D005158:Facial Paralysis / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D019786:Gadolinium DTPA; D016697:Herpes Zoster Oticus / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D009942:Organometallic Compounds; D004369:Pentetic Acid; D014725:Vestibular Nerve / Q000503:physiopathology
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA