Acquired immune deficiency syndrome-related pulmonary non-Hodgkin lymphoma regressing after zidovudine therapy.
BACKGROUND
Zidovudine is a thymidine analogue that has been reported to have antiviral and antineoplastic activity in vitro.


METHODS
The case of a patient with acquired immune deficiency syndrome (AIDS) and a pulmonary non-Hodgkin lymphoma treated with zidovudine and no other treatment is presented.


RESULTS
The patient achieved a prolonged partial remission of a pulmonary non-Hodgkin lymphoma while receiving zidovudine alone.


CONCLUSIONS
Zidovudine may have antitumor effects in AIDS-related lymphomas and should be evaluated for its antitumor potential.
Baselga
J
J
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
Krown
S E
SE
Telzak
E E
EE
Filippa
D A
DA
Straus
D J
DJ
D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D016483:Lymphoma, AIDS-Related / Q000188:drug therapy*; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy*; D008297:Male; D015215:Zidovudine / Q000627:therapeutic use*
D015215:Zidovudine