Relief of sickle cell priapism by hydralazine. Report of a case.
We report a 16-year-old Tanner IV male with homozygous hemoglobin S who presented with recurrent episodes of priapism unresponsive to standard therapy with hydration, analgesia, and exchange transfusion. He had a complete resolution of his symptoms with hydralazine therapy. We therefore suggest a trial of vasodilator therapy for recurrent sickle cell priapism before attempting surgical therapy.
Baruchel
S
S
Division of Hematology, McGill University, Montreal, Quebec, Canada.
Rees
J
J
Bernstein
M L
ML
Goodyer
P
P
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000628:therapy; D003131:Combined Modality Therapy; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use*; D008297:Male; D015995:Prevalence; D011317:Priapism / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D012008:Recurrence
D006830:Hydralazine