title: Refined algorithm and computer program for calculating all non-negative fluxes admissible in steady states of biochemical reaction systems with or without some flux rates fixed.
abstract: A refined algorithm together with a computer procedure for determining the complete set of non-negative, steady-state fluxes in biochemical reaction systems of any complexity, with or without some flux rates fixed, is given. It is shown that this set is a convex polyhedron, which may or may not be bounde. The algorithm is illustrated by several examples; one of them concerns intermediary metabolism. A computer code in standard C is presented.
authors.affiliation: Université Bordeaux II, Département de Biochimie Médicale et Biologie Moléculaire, France.
authors.forename: R
authors.initials: R
authors.lastname: Schuster
authors.forename: S
authors.initials: S
authors.lastname: Schuster
mesh_terms: D000465:Algorithms; D001669:Biochemical Phenomena; D001671:Biochemistry; D008954:Models, Biological; D011381:Programming Languages; D012984:Software