title: Effects of lorazepam on oxygen saturation before cardiac surgery.
abstract: We have studied patients presenting for coronary artery bypass surgery on two nights before surgery. Oxygen saturation during a night when the patient received no night sedation was compared with the night before surgery, when lorazepam 3-4 mg was given. There was no difference between the two nights when the total time at oxygen saturations less than 90% were compared, but the minimum oxygen saturation value when the patient received lorazepam was significantly smaller. No patient had significant sleep apnoea.
authors.affiliation: University Department of Anaesthesia, Glasgow Royal Infirmary.
authors.forename: J S
authors.initials: JS
authors.lastname: Pollock
authors.forename: G N
authors.initials: GN
authors.lastname: Kenny
mesh_terms: D001026:Coronary Artery Bypass; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008140:Lorazepam / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010100:Oxygen / Q000097:blood*; D011292:Premedication; D011300:Preoperative Care
chemical_list: D008140:Lorazepam; D010100:Oxygen