Current reproductive technology: considerations for the oncologist.
Advances in reproductive technology now afford options for certain cancer patients that the oncologist must consider when planning treatment. For men undergoing treatment likely to destroy testicular function, the development of sperm banks to store cryopreserved sperm offers the hope of future fatherhood. Cryopreserved sperm can be held indefinitely, with pregnancies via artificial insemination reported up to 15 years after freezing. For female cancer patients who will lose ovarian function but likely retain a viable womb, in vitro fertilization techniques hold the promise of pregnancy with the use of donated ova. In some cases, it may even be possible to extract the woman's own eggs before surgery and fertilize them with her husband's sperm. The resulting embryos, like sperm, can be frozen for indefinite future use. In the future, with new technological advances, extraction of ova for freezing at the time of ovarian extirpation may be a possibility.
Winkel
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Dept. of Obstetrics and Gynecology, Jefferson Medical College, Philadelphia, Pennsylvania.
Fossum
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D015925:Cryopreservation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007246:Infertility / Q000209:etiology / Q000628:therapy; D008297:Male; D009369:Neoplasms / Q000150:complications; D011247:Pregnancy; D012099:Reproductive Techniques; D012662:Semen Preservation