Relation between the intra-articular temperature of the temporomandibular joint and the presence of neuropeptide Y-like immunoreactivity in the joint fluid. A clinical study.
Arthritic temporomandibular joints were examined for the joint fluid content of neuropeptide Y-like immunoreactivity (NPY-LI) and the intra-articular temperature at two separate sessions. Sixteen patients (23 joints) with rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and unspecific polyarthritis or monarthritis were investigated in this study. The intra-articular temperature ranged between 35.6 and 37.5 degrees C. The concentration of NPY-LI ranged between 72.1 and 4466.0 pmol/l and was above the normal plasma level in all patients. The intra-articular temperature was negatively correlated with the joint fluid concentration of NPY-LI. Moreover, patients with low intra-articular temperature and high concentration of NPY-LI had a shorter duration of TMJ symptoms than those with high intra-articular temperature and low concentration of NPY-LI.
Appelgren
A
A
Department of Clinical Oral Physiology, Karolinska Institutet, Huddinge, Sweden.
Appelgren
B
B
Kopp
S
S
Lundeberg
T
T
Theodorsson
E
E
D000328:Adult; D000368:Aged; D001168:Arthritis / Q000097:blood / Q000378:metabolism* / Q000503:physiopathology*; D015535:Arthritis, Psoriatic / Q000097:blood / Q000378:metabolism / Q000503:physiopathology; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000378:metabolism / Q000503:physiopathology; D001831:Body Temperature; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009478:Neuropeptide Y / Q000032:analysis* / Q000097:blood; D013167:Spondylitis, Ankylosing / Q000097:blood / Q000378:metabolism / Q000503:physiopathology; D013582:Synovial Fluid / Q000737:chemistry*; D013705:Temporomandibular Joint Disorders / Q000097:blood / Q000378:metabolism* / Q000503:physiopathology*; D013997:Time Factors
D009478:Neuropeptide Y