title: Phenotypes of cytoskeletal mutants.
abstract: Phenotypic studies continue to contribute to an understanding of the functions of cytoskeletal proteins. Many of these studies indicate some degree of functional redundancy within a family of cytoskeletal proteins. Some surprises have emerged, such as suggestions of unexpected relationships between the actin and microtubule cytoskeletons. Finally, phenotypic studies have provided evidence for a function of intermediate filaments.
authors.affiliation: Department of Anatomy and Cell Biology, University of Michigan Medical School, Ann Arbor 48109-0616.
authors.forename: S S
authors.initials: SS
authors.lastname: Brown
mesh_terms: D000199:Actins / Q000235:genetics / Q000502:physiology; D000818:Animals; D003285:Contractile Proteins; D003598:Cytoskeletal Proteins / Q000235:genetics* / Q000502:physiology; D003599:Cytoskeleton; D005656:Fungal Proteins / Q000235:genetics; D005658:Fungi / Q000235:genetics; D007381:Intermediate Filament Proteins / Q000235:genetics / Q000502:physiology; D007448:Invertebrates / Q000235:genetics; D016547:Kinesins / Q000235:genetics / Q000502:physiology; D008840:Microfilament Proteins / Q000235:genetics / Q000502:physiology; D005810:Multigene Family; D009218:Myosins / Q000235:genetics / Q000502:physiology; D010641:Phenotype; D051304:Profilins
chemical_list: D000199:Actins; D003285:Contractile Proteins; D003598:Cytoskeletal Proteins; D005656:Fungal Proteins; D007381:Intermediate Filament Proteins; D008840:Microfilament Proteins; D051304:Profilins; D009218:Myosins; D016547:Kinesins