title: Male hypogonadotropic hypogonadism.
abstract: Hypogonadotropic hypogonadism in the male is caused by alterations in gonadotropin-releasing hormone secretion or through abnormal pituitary secretion of luteinizing hormone or follicle-stimulating hormone. Recent studies in animal and human models have demonstrated possible pathophysiologic explanations for the occurrence of some GnRH-deficient states. It is critical to ascertain whether such patients represent a variant of normal or have true hypogonadotropic hypogonadism. Recent developments in both diagnostic techniques and hormonal treatment increase the chances of a correct diagnosis and successful treatment outcome.
authors.affiliation: Department of Medicine, Massachusetts General Hospital, Boston.
authors.forename: R W
authors.initials: RW
authors.lastname: Whitcomb
authors.forename: W F
authors.initials: WF
authors.lastname: Crowley
mesh_terms: D003937:Diagnosis, Differential; D006065:Gonadotropins, Pituitary / Q000378:metabolism; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D007031:Hypothalamus / Q000503:physiopathology; D008297:Male
chemical_list: D006065:Gonadotropins, Pituitary