World-wide strategies for immunization against invasive Haemophilus influenzae type b disease.
Data available on the immunogenicity, safety and efficacy of Haemophilus influenzae type b (Hib) conjugate vaccines are encouraging and the prospects for controlling invasive Hib disease are good. The incidence of Hib meningitis in many industrialized countries increases sharply between 6 and 12 months of age and the first two doses of a Hib vaccine should ideally be given before that. In non-industrialized countries, the incidence peak is seen very early in life, which would require a very early start for Hib vaccination in such areas.
Iwarson
S
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Department of Infectious Diseases, University of Göteborg, Sweden.
D000293:Adolescent; D016667:Bacterial Capsules; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000008:administration & dosage; D006192:Haemophilus Infections / Q000453:epidemiology / Q000517:prevention & control*; D018073:Haemophilus Vaccines; D006193:Haemophilus influenzae / Q000145:classification / Q000276:immunology; D006801:Humans; D007115:Immunization Schedule; D007223:Infant; D007231:Infant, Newborn; D008583:Meningitis, Haemophilus / Q000453:epidemiology / Q000517:prevention & control; D011135:Polysaccharides, Bacterial / Q000008:administration & dosage / Q000494:pharmacology*
D001428:Bacterial Vaccines; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine; D011135:Polysaccharides, Bacterial