Hysteroscopic metroplasty in the diethylstilbestrol-exposed uterus and similar nonfusion anomalies: effects on subsequent reproductive performance; a preliminary report.
OBJECTIVE
To determine the feasibility of correcting the uterine abnormalities seen in diethylstilbestrol (DES)-exposed women and similar anomalies.


METHODS
Patients served as their own controls.


METHODS
University based and private practice tertiary referral practice.


METHODS
Eight patients referred for infertility, recurrent pregnancy loss, or both with an abnormal uterine contour as seen by hysterosalpingogram.


METHODS
Hysteroscopic metroplasty.


METHODS
Ability to conceive and carry pregnancy to livebirth.


RESULTS
Three of five patients with secondary infertility and recurrent pregnancy losses had livebirths as did a patient with secondary infertility. Two patients with primary infertility failed to conceive.


CONCLUSIONS
Metroplasty may decrease pregnancy loss in these patients but may not enhance fertility.
Nagel
T C
TC
Department of Obstetrics and Gynecology, University of Minnesota, Minneapolis.
Malo
J W
JW
D000014:Abnormalities, Drug-Induced / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D005298:Fertility; D006801:Humans; D015907:Hysteroscopy; D011247:Pregnancy; D011256:Pregnancy Outcome; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery*
D004054:Diethylstilbestrol