title: Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae.
abstract: The ENA2 gene encoding a P-type ATPase involved in Na+ and Li+ effluxes in Saccharomyces cerevisiae has been isolated. The putative protein encoded by ENA2 differs only in thirteen amino acids from the protein encoded by ENA1/PMR2. However, ENA2 has a very low level of expression and for this reason did not confer significant Li+ tolerance on a Li+ sensitive strain. ENA1 and ENA2 are the first two units of a tandem array of four highly homologous genes with probably homologous functions.
authors.affiliation: Departamento de Microbiología, Escuela Técnica Superior de Ingenieros Agrónomos, Madrid, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Garciadeblas
authors.forename: F
authors.initials: F
authors.lastname: Rubio
authors.forename: F J
authors.initials: FJ
authors.lastname: Quintero
authors.forename: M A
authors.initials: MA
authors.lastname: Bañuelos
authors.forename: R
authors.initials: R
authors.lastname: Haro
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Navarro
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics*; D001483:Base Sequence; D004274:DNA, Recombinant; D004352:Drug Resistance, Microbial; D015971:Gene Expression Regulation, Enzymologic; D005800:Genes, Fungal / Q000235:genetics*; D007527:Isoenzymes / Q000235:genetics*; D007763:Lac Operon / Q000235:genetics; D008094:Lithium / Q000378:metabolism / Q000494:pharmacology; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D012964:Sodium / Q000378:metabolism*
chemical_list: D004274:DNA, Recombinant; D007527:Isoenzymes; D008094:Lithium; D012964:Sodium; D000251:Adenosine Triphosphatases