Renal hypouricemia and absorptive hypercalciuria: a real syndrome.
We describe a case of renal hypouricemia due to increased tubular secretion of urate associated with absorptive hypercalciuria. This association has been described in the past, but this is the first time that high plasma levels of 1,25-dihydroxyvitamin D have been reported. A possible cause-and-effect relation between altered uric acid transport and altered vitamin D metabolism in the proximal tubule is suggested.
Uribarri
J
J
Department of Medicine, Mount Sinai Medical Center, New York, NY 10029-6574.
Oh
M S
MS
D000328:Adult; D001692:Biological Transport / Q000502:physiology; D002117:Calcitriol / Q000097:blood / Q000378:metabolism; D002118:Calcium / Q000652:urine*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000097:blood* / Q000503:physiopathology; D007687:Kidney Tubules, Proximal / Q000378:metabolism / Q000502:physiology; D013577:Syndrome; D014527:Uric Acid / Q000097:blood* / Q000493:pharmacokinetics
D014527:Uric Acid; D002117:Calcitriol; D002118:Calcium