title: Epidermoid carcinoma of the lung in stage I: factors of prognostic interest.
abstract: Factors affecting stage I epidermoid cancer of the lung were studied in a series of 29 patients treated only by surgery and followed up for ten years. A set of 13 variables with a possible influence on prognosis were investigated. The application of the Cox Univariate Analysis to the different variables showed the grade of cell differentiation and the mitotic index to be predictors. In the Cox Multivariate Analysis, the proportional regression equation revealed two independently significant variables (p < 0.01), which were the Mitotic Index and Nuclear Area. Grouping patients on the basis of the prognostic variables indicated allows a better prediction for survival to be made for this series of patients.
authors.affiliation: Lung and Chest Surgery Unit, University Hospital, Marqués de Valdecilla, Faculty of Medicine, University of Cantabria, Santander, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Carbajo
authors.forename: F J
authors.initials: FJ
authors.lastname: Ortega
authors.forename: M
authors.initials: M
authors.lastname: Hernández
authors.forename: R
authors.initials: R
authors.lastname: Ondiviela
authors.forename: C
authors.initials: C
authors.lastname: Blanco
authors.forename: L
authors.initials: L
authors.lastname: Buelta
authors.forename: F
authors.initials: F
authors.lastname: Garijo
authors.forename: F
authors.initials: F
authors.lastname: Val-Bernal
mesh_terms: D000367:Age Factors; D000368:Aged; D000704:Analysis of Variance; D001999:Bronchoscopy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002454:Cell Differentiation; D002467:Cell Nucleus / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008175:Lung Neoplasms / Q000473:pathology*; D008208:Lymphatic System / Q000473:pathology; D008297:Male; D008875:Middle Aged; D008940:Mitotic Index; D009336:Necrosis / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis; D011667:Pulmonary Veins / Q000473:pathology