[Psychiatric manifestations in Wilson's disease].
Wilson's disease is an inherited, autosomal recessive disease characterized by progressive hepatic and neurological symptoms. Clinical features usually start between the ages of 10 and 40. Psychiatric disturbances are present in almost all patients. In about a third of them psychiatric symptoms are present early in the disease and in almost 20% they precede hepatic and neurological dysfunction. In these cases the diagnosis of Wilson's disease is often difficult, as a result of which treatment is begun when the illness is already advanced. We report 3 patients with Wilson's disease in whom the psychiatric manifestations preceded neurological symptoms and necessitated admission for psychiatric treatment.
Schwartz
M
M
Neurology Dept., Bnai Zion Medical Center, Haifa.
Fuchs
S
S
Polak
H
H
Sharf
B
B
D000328:Adult; D006527:Hepatolenticular Degeneration / Q000523:psychology*; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000209:etiology*