Hepatitis viral markers in patients undergoing primary liver transplants.
The purpose of the study was to determine the prevalence in liver transplant (OLTx) patients of the hepatitis markers (anti-A, anti-B, anti-C, anti-D and HBsAg) and the interrelationships between markers and patients' sexes, ages, dates of transplant, clinicopathological diagnoses, and short-term survivals. Slightly more than half of the patients were male. Anti-A and anti-B were about evenly distributed between male and female. Anti-C, anti-D, and HBsAg were far more common in males. Age and year of transplant showed only a moderate increase in anti-A with increasing age. Anti-A was found in 57% of all patients, anti-B in 18%, anti-C in 17%, and HBsAg in 17%. Anti-D was tested only in patients who were positive for anti-B or HBsAg and occurred in 21 (11%) of 185. The poorest short-term survival occurred in males who showed both anti-A and HBsAg.
Lewis
J H
JH
Central Blood Bank, Pittsburgh, Pennsylvania 15219.
el-Ashmawy
L
L
Ramsey
G E
GE
Bontempo
F A
FA
Rochlani
M
M
Demetris
A J
AJ
Van Thiel
D H
DH
Starzl
T E
TE
D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006508:Hepatitis Antibodies / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006525:Hepatitis, Viral, Human / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D016031:Liver Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012737:Sex Factors; D016019:Survival Analysis; D013997:Time Factors
D006508:Hepatitis Antibodies; D006514:Hepatitis B Surface Antigens