Mutagenesis of the dehydratase active site in the erythromycin-producing polyketide synthase.
Bevitt
D J
DJ
Department of Biochemistry, University of Cambridge, U.K.
Staunton
J
J
Leadlay
P F
PF
D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D004917:Erythromycin / Q000096:biosynthesis; D064429:Fatty Acid Synthases / Q000737:chemistry / Q000235:genetics; D008969:Molecular Sequence Data; D009097:Multienzyme Complexes / Q000737:chemistry / Q000235:genetics*; D016297:Mutagenesis, Site-Directed; D051381:Rats; D016930:Saccharopolyspora / Q000201:enzymology / Q000235:genetics; D017386:Sequence Homology, Amino Acid
D009097:Multienzyme Complexes; D004917:Erythromycin; D064429:Fatty Acid Synthases