Chromosomal analysis of two neuroblastomas.
We report the results of cytogenetic analysis in two children with neuroblastoma. The analysis was performed on slides obtained from a 24-hour bone marrow (BM) culture or by a direct method of the primary tumor tissue. The structural and numeric karyotype aberrations were established, including structural aberrations of chromosome 1. The finding of i(1q) and t(1;5)(p22;q13) is of interest because these chromosome aberrations are rare in this type of disease.
Petković
I
I
Institute for Mother and Child Health, Faculty of Medicine, University of Zagreb, Croatia.
Nakić
M
M
Cepulić
M
M
Konja
J
J
D000008:Abdominal Neoplasms / Q000235:genetics*; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000235:genetics*; D002878:Chromosomes, Human, Pair 1; D002895:Chromosomes, Human, Pair 5; D005260:Female; D006801:Humans; D008297:Male; D009447:Neuroblastoma / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics