[The pulmonary toxicity of amiodarone in our hospital: apropos 8 cases].
We present the most relevant data of a series of 8 cases of PTA coming from our environment. We highlight the onset of PTA with low doses of amiodarone (equal or lower than 400 mg/day), the affectation of only aged patients (range 63-77 years) and always, except in one case, during the first five years of treatment with amiodarone. Dyspnea was the most frequent symptom. The definition of PTA is mainly clinical-radiological and it has no biochemical, radiological or functional unique characteristics, determining the need for a careful differential diagnosis. The prognosis was excellent when the administration of amiodarone was stopped and, in some cases, steroids were added.
Nistal de Paz
F
F
Sección de Neumología, Complejo Hospitalario del Insalud, León.
Allende González
J
J
Herrero Fernández
B
B
Cabreros Pisonero
E
E
Möller Bustinza
I
I
Pérez Laiz
C
C
Costilla García
S
S
D000368:Aged; D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D011859:Radiography; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D013997:Time Factors
D000638:Amiodarone