Bone marrow transplantation: a children's hospital of New Orleans experience.
Bone marrow transplantation has become an important therapeutic strategy in the treatment of pediatric malignancies and certain congenital disorders. We initiated a bone marrow transplant program at Children's Hospital in New Orleans at the start of January 1989. Both allogeneic and autologous bone marrow transplantations have been performed. To date, a total of 20 children have received transplants for a variety of diseases. Their ages ranged from 17 months to 20 years. The overall 2-year survival is 40%. For the good-risk patients, the projected 2-year disease-free survival is 85%, compared to 30% for the poor-risk patients. Regimen-related mortality has been extremely low in our settings primarily due to improvement of available supportive care. We conclude that bone marrow transplantation offers a potential cure for these otherwise fatal diseases.
Yu
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LC
Louisiana State University Medical Center, New Orleans.
Ode
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Warrier
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D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation / Q000379:methods* / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D005260:Female; D006776:Hospitals, Pediatric; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D008145:Louisiana; D008297:Male; D011379:Prognosis; D016019:Survival Analysis