title: Comprehensive inpatient treatment for intractable migraine: a prospective long-term outcome study.
abstract: This paper describes outcome data for 100 patients with severe, intractable, persistent migraine (chronic daily headache), who were admitted to a comprehensive inpatient Head-Pain Treatment Unit for a mean of 8.5 days. Headache, pain-related behavior, depression, sleep disturbance, functional performance, work status, and medication use were assessed at admission, post-discharge (mean = 2.3 weeks) and long-term follow-up (mean = 8.3 months). Significant improvement noted two weeks after discharge was maintained over time. Long-term results revealed a 64% reduction in the mean number of days in a 2-week period with severe to incapacitating headache (6.29 to 2.26), with a corresponding increase in pain-free days (1.03 to 5.40). At follow-up, the frequency of severe headaches was reduced by at least 50% for 75% of the patients. The mean rating of overall improvement was 74%. Patients on work-leave due to pain dropped from 24% to 4%, while the number of working patients rose from 31% to 53%. The data showed statistically significant reductions in days lost to pain, depression, sleep disturbance, and use of symptomatic medication. All the above analyses were significant at P = .000. These results demonstrate the efficacy of the inpatient headache program intervention for this group of patients.
authors.affiliation: Michigan Head-Pain and Neurological Institute, Ann Arbor 48104.
authors.forename: A E
authors.initials: AE
authors.lastname: Lake
authors.forename: J R
authors.initials: JR
authors.lastname: Saper
authors.forename: S F
authors.initials: SF
authors.lastname: Madden
authors.forename: C
authors.initials: C
authors.lastname: Kreeger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use; D001519:Behavior / Q000502:physiology; D003863:Depression / Q000523:psychology; D006760:Hospitalization; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D010147:Pain Measurement; D017060:Patient Satisfaction; D011379:Prognosis; D011446:Prospective Studies; D012893:Sleep Wake Disorders / Q000503:physiopathology; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D000700:Analgesics