title: Elevated human chorionic gonadotropin levels in pregnancies with sex chromosome abnormalities.
abstract: Numerous reports have dealt with the usefulness of the maternal serum alpha-fetoprotein marker (MsAFP) and human chorionic gonadotropin (MshCG) levels in the detection of Down syndrome (DS) and other autosomal trisomies. Only few reports have discussed the possible association of elevated levels of MshCG and sex chromosome aneuploidy. We wish to report on 3 cases in which this association was found.
authors.affiliation: Genetics Unit, Sapir Medical Center, Meir General Hospital, Kfar-Saba, Israel.
authors.forename: I
authors.initials: I
authors.lastname: Barnes-Kedar
authors.forename: A
authors.initials: A
authors.lastname: Amiel
authors.forename: O
authors.initials: O
authors.lastname: Maor
authors.forename: M
authors.initials: M
authors.lastname: Fejgin
mesh_terms: D000328:Adult; D000782:Aneuploidy; D015415:Biomarkers; D006063:Chorionic Gonadotropin / Q000097:blood*; D005260:Female; D005315:Fetal Diseases / Q000097:blood / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007713:Klinefelter Syndrome / Q000097:blood / Q000175:diagnosis; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000175:diagnosis; D011296:Prenatal Diagnosis; D012729:Sex Chromosome Aberrations / Q000097:blood* / Q000175:diagnosis
chemical_list: D015415:Biomarkers; D006063:Chorionic Gonadotropin