Membranous nephropathy associated with nodular sclerosing Hodgkin's disease.
A 61-year-old man developed steroid-resistant nephrotic syndrome in which renal biopsy showed membranous nephropathy. Six months after the initial presentation, nodular sclerosing Hodgkin's disease was diagnosed. Cyclophosphamide, vincristine, prednisolone and procariazine chemotherapy was administered, after which proteinuria gradually decreased resulting in complete remission in the course of 7 months. A second renal biopsy, which was undertaken 4 months after complete remission, revealed significant histological improvement with disappearance of immune deposit.
Hotta
O
O
Department of Nephrology, Sendai Shakaihoken Hospital, Japan.
Taguma
Y
Y
Kurosawa
K
K
Sudo
K
K
Takahashi
H
H
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D015433:Glomerulonephritis, Membranous / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006689:Hodgkin Disease / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D011344:Procarbazine / Q000627:therapeutic use; D011507:Proteinuria / Q000150:complications; D014750:Vincristine / Q000627:therapeutic use
D011344:Procarbazine; D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone