Intramedullary spinal sarcoidosis: clinical and magnetic resonance imaging characteristics.
We present a retrospective series of the clinical and MRI findings in 16 patients with intramedullary spinal sarcoidosis (ISS), including 12 patients studied with gadolinium-DTPA. The spectrum of MRI findings includes leptomeningeal enhancement, fusiform spinal cord enlargement, focal or diffuse intramedullary disease, and spinal cord atrophy. We present a classification of ISS correlating the clinical progression and the temporal sequence of MRI abnormalities. Improvement occurred in five of 12 patients (42%) treated with immunosuppressive therapy.
Junger
S S
SS
North Central Neurology, Denville, NJ 07834.
Stern
B J
BJ
Levine
S R
SR
Sipos
E
E
Marti-Masso
J F
JF
D000328:Adult; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D012507:Sarcoidosis / Q000473:pathology*; D013118:Spinal Cord Diseases / Q000473:pathology*
D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA