MsmE, a lipoprotein involved in sugar transport in Streptococcus mutans.
Metabolic labelling by [14C]palmitic acid showed that growth of Streptococcus mutans LT11 in raffinose, an inducer of the msm operon, resulted in increased production of a 45-kDa lipoprotein corresponding to MsmE, which is believed to be a sugar-binding protein. MsmE was also labelled when an msmE clone was expressed in Escherichia coli. The presence of a lipid anchor on MsmE provides a likely explanation of how the sugar-binding protein component of the msm binding protein-dependent multiple sugar transport system is retained at the cell surface.
Sutcliffe
I C
IC
Department of Oral Biology, Dental School, University of Newcastle Upon Tyne, United Kingdom.
Tao
L
L
Ferretti
J J
JJ
Russell
R R
RR
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001692:Biological Transport; D050260:Carbohydrate Metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D008074:Lipoproteins / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D013295:Streptococcus mutans / Q000235:genetics / Q000378:metabolism*
D001426:Bacterial Proteins; D008074:Lipoproteins