Starfish saponins, part 49. New cytotoxic steroidal glycosides from the starfish Fromia monilis.
Nine new cytotoxic steroidal glycosides 1-9 have been isolated from the starfish Fromia monilis collected off New Caledonia. Structures of these compounds, which include four mono-(1-4), two di-(5,6), and three glycosides (7-9), were elucidated through spectral interpretation. Monilosides G [7], H [8], and I [9] are the first tri-glycosides to be found among the group of glycosides of polyhydroxilated steroids from starfishes.
Casapullo
A
A
Dipartimento di Chimica della Sostanze Naturali, Università degli Studi di Napoli "Federico II.", Italy.
Finamore
E
E
Minale
L
L
Zollo
F
F
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D006027:Glycosides / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D012503:Saponins / Q000302:isolation & purification* / Q000494:pharmacology; D013215:Starfish / Q000737:chemistry*; D013256:Steroids / Q000302:isolation & purification* / Q000494:pharmacology; D014709:Vero Cells / Q000187:drug effects
D000970:Antineoplastic Agents; D006027:Glycosides; D012503:Saponins; D013256:Steroids