title: A model for prosthetogenic enzyme amplification assays.
abstract: A mathematical model describing the behaviour of a new class of prosthetogenic enzyme amplification assays is described. The predictions of the model are favourably compared with an enzyme amplification assay for alkaline phosphatase. The model is used to kinetically characterise and optimise the enzyme amplification assay.
authors.affiliation: London Biotechnology Limited, Department of Biochemistry and Molecular Biology, University College London, UK.
authors.forename: S
authors.initials: S
authors.lastname: Harbron
authors.forename: M
authors.initials: M
authors.lastname: Fisher
authors.forename: B R
authors.initials: BR
authors.lastname: Rabin
mesh_terms: D000469:Alkaline Phosphatase / Q000032:analysis / Q000737:chemistry; D004798:Enzymes / Q000032:analysis* / Q000737:chemistry; D005182:Flavin-Adenine Dinucleotide; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008956:Models, Chemical
chemical_list: D004798:Enzymes; D005182:Flavin-Adenine Dinucleotide; D000469:Alkaline Phosphatase