Growth mechanisms and cancer progression.
In the final stages of malignant progression, tumor cell growth mechanisms become self-contained, making the cells impervious to attempts at growth control by physicians or the host. Such tactics might work better in the early stages of metastasis, when these cells are still responsive to outside influences.
Nicolson
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Department of Tumor Biology, University of Texas M.D. Anderson Cancer Center, Houston.
D000818:Animals; D016207:Cytokines / Q000235:genetics / Q000502:physiology; D015870:Gene Expression / Q000235:genetics; D006133:Growth Substances / Q000235:genetics / Q000502:physiology; D006801:Humans; D051379:Mice; D008954:Models, Biological; D008957:Models, Genetic; D009362:Neoplasm Metastasis / Q000235:genetics / Q000503:physiopathology*; D009369:Neoplasms / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy; D011990:Receptors, Transferrin / Q000235:genetics / Q000502:physiology; D014162:Transfection; D014407:Tumor Cells, Cultured / Q000502:physiology
D016207:Cytokines; D006133:Growth Substances; D011990:Receptors, Transferrin