A model of stereociliary tip-link stretches.
A model of the tip-link stretches produced by angular deflections of the stereocilia of vertebrate acoustico-lateralis hair cells is presented. It is shown that tip-link stretch in the model is proportional to the angle of stereociliary deflection. By contrast, the stretch of a horizontal (e.g., row-to-row) link is proportional to the square of the angle of stereociliary deflection. Possible roles of these stretches in sensory transduction are discussed.
Geisler
C D
CD
Department of Neurophysiology, University of Wisconsin-Madison 53706.
D000818:Animals; D002923:Cilia / Q000502:physiology; D006198:Hair Cells, Auditory / Q000502:physiology*; D008433:Mathematics; D008954:Models, Biological; D014714:Vertebrates