Possible etiology for euthyroid sick syndrome.
Euthyroid sick syndrome is possibly due to an increase in Triac (a T3 analogue) and/or Tetrac (a T4 analogue). Triac and/or Tetrac possibly feed back on the pituitary/hypothalamus region and cause a secondary hypothyroidism. This is possibly analogous to such diverse conditions as fetal thyroid function and black bear hibernation.
Carlin
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Endocrinology Dept, Brooke Army Medical Center, San Antonio, Texas 78234.
Carlin
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D000818:Animals; D005067:Euthyroid Sick Syndromes / Q000209:etiology* / Q000378:metabolism; D005246:Feedback; D005943:Gluconeogenesis; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism; D007037:Hypothyroidism / Q000209:etiology / Q000378:metabolism; D008954:Models, Biological; D013974:Thyroxine / Q000031:analogs & derivatives / Q000378:metabolism; D014284:Triiodothyronine / Q000031:analogs & derivatives / Q000378:metabolism
D014284:Triiodothyronine; C010642:3,3',5-triiodothyroacetic acid; C011126:tetraiodothyroacetic acid; D013974:Thyroxine