title: A recurrent chondromyxoid fibroma with chromosome aberrations ins(5;2)(q13;p21p25) and 2p deletion: a case report.
abstract: We report a patient with a recurrent chondromyxoid fibroma, a rare benign tumor of the bone with clonal aberrations in chromosomes 2 and 5. Karyotyping, chromosome painting, interphase cytogenetics by in situ hybridization, and DNA flow cytometry were used. The karyotype was interpreted as 46,XX,der(2)ins(5;2)(q13;p21p25),der(2)ins(5;2)(q13;p21p25), der(5)ins(5;2) (q13;p21p25).
authors.affiliation: Department of Medical Genetics, University of Helsinki, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Tarkkanen
authors.forename: T
authors.initials: T
authors.lastname: Böhling
authors.forename: H
authors.initials: H
authors.lastname: Heliö
authors.forename: E
authors.initials: E
authors.lastname: Karaharju
authors.forename: A
authors.initials: A
authors.lastname: Kaipainen
authors.forename: J
authors.initials: J
authors.lastname: Szymanska
authors.forename: I
authors.initials: I
authors.lastname: Elomaa
authors.forename: S
authors.initials: S
authors.lastname: Knuutila
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000235:genetics* / Q000601:surgery; D002812:Chondroma / Q000235:genetics* / Q000601:surgery; D002878:Chromosomes, Human, Pair 1; D002881:Chromosomes, Human, Pair 12; D002889:Chromosomes, Human, Pair 2; D002895:Chromosomes, Human, Pair 5; D002897:Chromosomes, Human, Pair 7; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D007621:Karyotyping; D009364:Neoplasm Recurrence, Local / Q000235:genetics* / Q000601:surgery; D011884:Radius / Q000601:surgery; D012086:Reoperation; D014178:Translocation, Genetic / Q000235:genetics*; D014314:Trisomy
chemical_list: D004273:DNA, Neoplasm