title: Topical retinoids. Their uses in dermatology.
abstract: The retinoids provide an important new way of treating dermatologic disorders. They have also proved to have a role in the prevention of new lesion formation. New retinoids, of which adapalene is one, have recently been synthesized in order to obtain similar or better efficacy while reducing skin irritation potential. These new molecules are currently under clinical investigation. Preliminary results are encouraging. In the near future, an expanded range of topical retinoids should be available.
authors.affiliation: Clinical Research Department, Valbonne, France.
authors.forename: M
authors.initials: M
authors.lastname: Verschoore
authors.forename: M
authors.initials: M
authors.lastname: Bouclier
authors.forename: J
authors.initials: J
authors.lastname: Czernielewski
authors.forename: C
authors.initials: C
authors.lastname: Hensby
mesh_terms: D000068816:Adapalene; D000279:Administration, Cutaneous; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D006801:Humans; D015474:Isotretinoin / Q000627:therapeutic use; D051379:Mice; D008954:Models, Biological; D009281:Naphthalenes / Q000627:therapeutic use; D011565:Psoriasis / Q000188:drug therapy; D012176:Retinoids / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D015595:Skin Aging / Q000187:drug effects; D012871:Skin Diseases / Q000188:drug therapy*; D014212:Tretinoin / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009281:Naphthalenes; D012176:Retinoids; D000068816:Adapalene; D014212:Tretinoin; D015474:Isotretinoin