title: Vacuum measurement in steam sterilizable lyophilizers.
abstract: This paper discusses the performance and sterilizability attributes of several different types of capacitance manometers as used in steam sterilizable lyophilizers. Recommendations are made for proper capacitance manometer selection, installation, operation, and calibration. An overview of vacuum gauging methods and the performance and sterility benefits of a new high-temperature (125 degrees C)/high-overpressure capacitance manometer are discussed.
authors.affiliation: MKS Instruments, Inc., Andover, MA.
authors.forename: J
authors.initials: J
authors.lastname: Welch
mesh_terms: D002138:Calibration; D004345:Drug Industry / Q000295:instrumentation*; D004867:Equipment Design; D005612:Freeze Drying / Q000295:instrumentation*; D008365:Manometry; D011312:Pressure; D013227:Steam; D013242:Sterilization / Q000379:methods*; D014618:Vacuum
chemical_list: D013227:Steam