title: Serum lactate dehydrogenase in head and neck malignancy patients.
abstract: 50 patients of head and neck malignancy were selected for this study while excluding those associated with renal, hepatic, cardiac and metabolic diseases. Age and sex matched even number of controls were also included for comparison. Serum LDH levels in the control group were 124.2 +/- 3.50 I.U./L. Higher levels of LDH were observed in patients with malignancy of head and neck (335.50 +/- 21.60 I.U./L, P < 0.001). Serum LDH level was also related to histopathological stage of malignancy, being higher in poorly differentiated tumour as compared to moderate and well differentiated malignancy. Patients without metastasis had insignificantly lower serum LDH levels as compared to those with metastasis.
authors.affiliation: Department of Otorhinolaryngology, J.N. Medical College, Aligarh Muslim University.
authors.forename: S K
authors.initials: SK
authors.lastname: Singh
authors.forename: S A
authors.initials: SA
authors.lastname: Hasan
authors.forename: S C
authors.initials: SC
authors.lastname: Sharma
authors.forename: K
authors.initials: K
authors.lastname: Chandra
authors.forename: R
authors.initials: R
authors.lastname: Ali
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D006258:Head and Neck Neoplasms / Q000201:enzymology*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor; D007770:L-Lactate Dehydrogenase