Management of vitiligo.
Vitiligo is a disease of unknown origin that causes destruction of melanocytes in the skin, mucous membranes, the eyes, and occasionally in hairbulbs and in the ears. The loss of melanocytes alters both structure and function of these organs. The goals of therapy are multifold. The primary goal is to restore melanocytes to the skin so that the epidermis has a normal morphology. Such repigmented skin regains its normal immune/inflammatory functions.
Nordlund
J J
JJ
Department of Dermatology, University of Cincinnati, Ohio.
Halder
R M
RM
Grimes
P
P
D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D002648:Child; D003869:Dermabrasion; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008074:Lipoproteins / Q000627:therapeutic use; D008297:Male; D008544:Melanocytes / Q000637:transplantation; D011701:PUVA Therapy; D010924:Placental Extracts / Q000627:therapeutic use; D011613:Psychotherapy; D016038:Skin Transplantation; D013473:Sunscreening Agents / Q000627:therapeutic use; D013653:Tattooing; D014467:Ultraviolet Therapy; D014820:Vitiligo / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*
D004365:Drugs, Chinese Herbal; D008074:Lipoproteins; C070432:Melagenine; D010924:Placental Extracts; D013473:Sunscreening Agents; D005472:Fluorouracil