Effect of calcium channel blockers on serum levels of thyroid hormones.
One month oral therapy with calcium channel blockers caused significant (P < 0.001) decrease in serum levels of triiodothyronine and thyroxine and significant increase in serum levels of thyroid stimulating hormone in rabbits. Most probable mechanism of action was block in the synthesis and/or release of thyroid hormones.
Mittal
S R
SR
J.L.N. Medical College, AJMER, Rajasthan, India.
Mathur
A K
AK
Prasad
N
N
D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D011817:Rabbits; D013961:Thyroid Gland / Q000187:drug effects; D013963:Thyroid Hormones / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D002121:Calcium Channel Blockers; D013963:Thyroid Hormones; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine