title: The morquio A syndrome (mucopolysaccharidosis IVA) gene maps to 16q24.3.
abstract: The gene for N-acetylgalactosamine-6-sulfatase, the deficiency of which results in Morquio A syndrome (mucopolysaccharidosis type IVA), was assigned to chromosome 16 at band q24.3 by fluorescence in situ hybridization. Localization of this band was confirmed by PCR analysis of a somatic cell hybrid panel used for fine mapping of chromosome 16.
authors.affiliation: Department of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital, Australia.
authors.forename: E
authors.initials: E
authors.lastname: Baker
authors.forename: X H
authors.initials: XH
authors.lastname: Guo
authors.forename: A M
authors.initials: AM
authors.lastname: Orsborn
authors.forename: G R
authors.initials: GR
authors.lastname: Sutherland
authors.forename: D F
authors.initials: DF
authors.lastname: Callen
authors.forename: J J
authors.initials: JJ
authors.lastname: Hopwood
authors.forename: C P
authors.initials: CP
authors.lastname: Morris
mesh_terms: D000818:Animals; D001483:Base Sequence; D002811:Chondroitinsulfatases / Q000172:deficiency / Q000235:genetics*; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D004277:DNA, Single-Stranded; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D009085:Mucopolysaccharidosis IV / Q000235:genetics*; D016133:Polymerase Chain Reaction
chemical_list: D004277:DNA, Single-Stranded; D002811:Chondroitinsulfatases