Measured dose to ovaries and testes from Hodgkin's fields and determination of genetically significant dose.
OBJECTIVE
To determine the genetically significant dose from therapeutic radiation exposure with Hodgkin's fields by estimating the doses to ovaries and testes.


METHODS
Phantom measurements were performed to verify estimated doses to ovaries and testes from Hodgkin's fields. Thermoluminescent LiF dosimeters (TLD-100) of 1 x 3 x 3 mm3 dimensions were embedded in phantoms and exposed to standard mantle and paraaortic fields using Co-60, 4 MV, 6 MV, and 10 MV photon beams.


RESULTS
Our results show that measured doses to ovaries and testes are about two to five times higher than the corresponding graphically estimated doses for Co-60 and 4 MVX photon beams as depicted in ICRP publication 44. In addition, the measured doses to ovaries and testes are about 30% to 65% lower for 10 MV photon beams than for their corresponding Co-60 photon beams.


CONCLUSIONS
The genetically significant dose from Hodgkin's treatment (less than 0.01 mSv) adds about 4% to the genetically significant dose contribution to medical procedures and adds less than 1% to the genetically significant dose from all sources. Therefore, the consequence to society is considered to be very small. The consequences for the individual patient are, likewise, small.
Niroomand-Rad
A
A
Department of Radiation Medicine, Georgetown University Medical Center, Washington, DC.
Cumberlin
R
R
D000016:Abnormalities, Radiation-Induced / Q000453:epidemiology / Q000209:etiology*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008953:Models, Anatomic; D010053:Ovary / Q000033:anatomy & histology / Q000528:radiation effects*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011827:Radiation; D011878:Radiotherapy / Q000009:adverse effects* / Q000379:methods; D011879:Radiotherapy Dosage; D013737:Testis / Q000033:anatomy & histology / Q000528:radiation effects*
D003037:Cobalt Radioisotopes