Low-dose apomorphine challenge in tardive akathisia.
We challenged seven tardive akathisia patients with low-dose apomorphine (0.01 mg/kg) SC and placebo in a double-blind, random design. Apomorphine caused a significantly greater reduction in the objective (movement) but not the subjective (distress) component of akathisia.
Sachdev
P
P
Neuropsychiatric Institute, Prince Henry Hospital, Sydney, Australia.
Loneragan
C
C
D000328:Adult; D000368:Aged; D017109:Akathisia, Drug-Induced / Q000188:drug therapy*; D001058:Apomorphine / Q000008:administration & dosage*; D004298:Dopamine / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos
D010919:Placebos; D001058:Apomorphine; D004298:Dopamine