title: Factors associated with occurrence of large vessel and lacunar cerebral infarctions.
abstract: A stroke registry was developed to determine the localizing value of various clinical data. Adequate localization was achieved in 98% of 246 patients with infarcts. Among 212 male patients with cerebral infarcts not due to cardiogenic embolism or an unusual etiology, there were 152 with large-vessel and 59 with lacunar infarcts. Logistic regression analysis of factors associated with large vessel and lacunar stroke identified myocardial infarction on ECG as the only statistically significant variable; its presence was associated with an odds ratio for lacunar infarction of 0.19 (95% confidence interval 0.06-0.66) (P = 0.009). Logistic regression analysis of factors associated with anterior and posterior circulation large vessel stroke identified pack years of smoking as the only statistically significant variable; the odds ratio for posterior circulation infarction for a 10-year increment in pack years of smoking was 0.83 (95% confidence interval 0.73-0.94) (P = 0.0035).
authors.affiliation: GRECC (182), Veterans Administration Medical Center, Gainesville, FL 32608-1197.
authors.forename: S E
authors.initials: SE
authors.lastname: Nadeau
authors.forename: J E
authors.initials: JE
authors.lastname: Jordan
authors.forename: S K
authors.initials: SK
authors.lastname: Mishra
mesh_terms: D000367:Age Factors; D000704:Analysis of Variance; D002536:Cerebral Arteries / Q000473:pathology / Q000503:physiopathology; D002544:Cerebral Infarction / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology; D016017:Odds Ratio; D044469:Racial Groups; D012042:Registries; D012044:Regression Analysis; D013599:Systole; D014280:Triglycerides / Q000097:blood
chemical_list: D014280:Triglycerides; D003404:Creatinine