title: Acquired growth hormone deficiency due to pituitary stalk transection after head trauma in childhood.
abstract: Two patients are reported with growth hormone deficiency due to head trauma in childhood. Although their injuries were outwardly only slight and there was no loss of consciousness and no subsequent neurological deficits, they exhibited gradual growth retardation from the time of the trauma. Provocative endocrinological tests showed growth hormone deficiency and MRI showed transection of the pituitary stalk. These findings suggest that ordinary head trauma, as well as perinatal insult and congenital abnormalities, could be a cause of growth hormone deficiency.
authors.affiliation: Department of Pediatrics, Kyoto University Faculty of Medicine, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Yamanaka
authors.forename: T
authors.initials: T
authors.lastname: Momoi
authors.forename: I
authors.initials: I
authors.lastname: Fujisawa
authors.forename: K
authors.initials: K
authors.lastname: Kikuchi
authors.forename: M
authors.initials: M
authors.lastname: Kaji
authors.forename: H
authors.initials: H
authors.lastname: Sasaki
authors.forename: T
authors.initials: T
authors.lastname: Yorifuji
authors.forename: H
authors.initials: H
authors.lastname: Mikawa
mesh_terms: D002648:Child; D002828:Choristoma; D006259:Craniocerebral Trauma / Q000150:complications* / Q000175:diagnosis; D006130:Growth Disorders / Q000209:etiology*; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010902:Pituitary Gland / Q000293:injuries* / Q000473:pathology; D010904:Pituitary Gland, Posterior; D010911:Pituitary Neoplasms
chemical_list: D013006:Growth Hormone