title: Fetal anaemia and its relation with increased concentrations of adenosine.
abstract: Adenosine concentrations were measured in umbilical venous blood obtained by cordocentesis from 14 fetuses of 19-34 weeks' gestation. The concentration did not change significantly with gestational age, but anaemic fetuses showed significantly increased concentrations of adenosine and there was a positive association with blood oxygen tension. These findings suggest that the fetus responds to tissue hypoxia by increasing blood adenosine concentrations from at least 19 weeks' gestation.
authors.affiliation: Department of Child Health, Kings College Hospital, London.
authors.forename: R I
authors.initials: RI
authors.lastname: Ross Russell
authors.forename: A
authors.initials: A
authors.lastname: Greenough
authors.forename: H
authors.initials: H
authors.lastname: Lagercrantz
authors.forename: I
authors.initials: I
authors.lastname: Dahlin
authors.forename: K
authors.initials: K
authors.lastname: Nicolaides
mesh_terms: D000241:Adenosine / Q000097:blood*; D000740:Anemia / Q000097:blood*; D017218:Cordocentesis; D003430:Cross-Sectional Studies; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005315:Fetal Diseases / Q000097:blood*; D005865:Gestational Age; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D011247:Pregnancy
chemical_list: D006454:Hemoglobins; D000241:Adenosine