title: Possible role of a choline-containing teichoic acid in the maintenance of normal cell shape and physiology in Streptococcus oralis.
abstract: Streptococcus oralis ATCC 35037 took up radioactively labeled choline from growth medium. Most of the choline (80 to 90%) was incorporated into the cell wall teichoic acid, and about 10% was localized in the plasma membrane. While cells grew in choline-free medium, they did so at slow rates and produced cell walls with greatly reduced amounts of phosphate and no detectable choline. Cells grown in choline-free medium had grossly abnormal shape and size. Both biochemical and morphological abnormalities were reversible by addition of choline to the medium.
authors.affiliation: Department of Microbiology, Weber State University, Ogden, Utah 84408-2506.
authors.forename: D S
authors.initials: DS
authors.lastname: Horne
authors.forename: A
authors.initials: A
authors.lastname: Tomasz
mesh_terms: D002794:Choline / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D003470:Culture Media; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D013291:Streptococcus / Q000166:cytology* / Q000254:growth & development / Q000378:metabolism; D013682:Teichoic Acids / Q000378:metabolism*
chemical_list: D003470:Culture Media; D013682:Teichoic Acids; D002794:Choline