title: The discovery and development of new antileukemic drugs.
abstract: Despite the major advances that have been made over the past few decades in the management of adult acute leukemia, a substantial number of the patients still die from the underlying disease. Therefore, it is essential that we vigorously pursue efforts to discover and develop novel therapeutic agents for the treatment of leukemia.
authors.affiliation: Division of Cancer Treatment, National Cancer Institute, Bethesda, Maryland.
authors.forename: M
authors.initials: M
authors.lastname: Grever
authors.forename: L
authors.initials: L
authors.lastname: Malspeis
mesh_terms: D000208:Acute Disease; D000328:Adult; D000818:Animals; D000970:Antineoplastic Agents / Q000145:classification / Q000494:pharmacology / Q000627:therapeutic use; D015195:Drug Design; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D004351:Drug Resistance; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*; D007942:Leukemia, Experimental / Q000188:drug therapy; D009316:National Institutes of Health (U.S.); D014481:United States
chemical_list: D000970:Antineoplastic Agents