Muir-Torre syndrome associated with a family history of hyperlipidemia.
The Muir-Torre syndrome is a rare disorder characterized by sebaceous neoplasms of the skin and multiple visceral malignancies. The syndrome appears to be a familial, autosomal dominant condition. We diagnosed this syndrome in a previously unreported patient and found a personal and family history of malignancies and hyperlipidemia. The association of Muir-Torre syndrome with a family history of hyperlipidemia, another autosomal dominant condition, has not been previously reported. The possible genetic relationship between the two disorders is discussed.
Ródenas
J M
JM
Department of Dermatology, Hospital Universitario, Granada, Spain.
Herranz
M T
MT
Tercedor
J
J
López
B
B
Naranjo
R
R
Delgado
V
V
D000368:Aged; D006801:Humans; D006950:Hyperlipidemia, Familial Combined / Q000150:complications* / Q000235:genetics; D007414:Intestinal Neoplasms / Q000150:complications* / Q000235:genetics; D008297:Male; D009386:Neoplastic Syndromes, Hereditary / Q000150:complications* / Q000235:genetics; D010375:Pedigree; D012626:Sebaceous Gland Neoplasms / Q000150:complications* / Q000235:genetics; D013577:Syndrome