Alterations in the lipid composition of seminal plasma in patients with a chronic infection of the urogenital tract.
The lipid composition of seminal plasma was studied in 15 control subjects and 21 patients consulting for hypofertility and showing a chronic infection of the urogenital tract. In the infected patients a significant reduction in total cholesterol, HDL cholesterol and total phospholipids was noted. Moreover, there is a significant correlation between the rates of total cholesterol and prostatic acid phosphatases and the rates of phospholipids and proteins in seminal plasma. Knowing the role of lipids in the phenomena of maturation and capacitation of spermatozoa, such modifications enable us to understand better the functional anomalies of sperm observed in patients with chronic infection of the urogenital tract and also enable us to explain the effects of the infection on fertility.
Vignon
F
F
Groupe de Recherche en Andrologie, Faculté de Médecine, Université Louis-Pasteur, Strasbourg, France.
Clavert
A
A
Cranz
C
C
Koll-Back
M H
MH
Reville
P
P
D000135:Acid Phosphatase / Q000032:analysis; D000328:Adult; D002908:Chronic Disease; D006801:Humans; D007239:Infections / Q000150:complications / Q000378:metabolism*; D007248:Infertility, Male / Q000150:complications / Q000378:metabolism; D008055:Lipids / Q000032:analysis*; D008297:Male; D052801:Male Urogenital Diseases / Q000150:complications / Q000378:metabolism*; D011506:Proteins / Q000032:analysis; D012661:Semen / Q000737:chemistry*
D008055:Lipids; D011506:Proteins; D000135:Acid Phosphatase