Epidermodysplasia verruciformis and malignant thymoma.
We describe a patient with a long history of skin lesions clinically and histologically consistent with epidermodysplasia verruciformis (EV) who developed malignant thymoma. HPV-9DNA was found in the macular lesion and HPV-4DNA and HPV-9DNA in the coexistent common warts. Thrombocytopenia and hypogammaglobulinaemia preceded the diagnosis of thymoma. Our patient seems to represent an example of an EV-like syndrome in immunodeficiency.
Jacyk
W K
WK
Department of Dermatology, University of Pretoria, Republic of South Africa.
Hazelhurst
J A
JA
Dreyer
L
L
Coccia-Portugal
M A
MA
D000328:Adult; D004819:Epidermodysplasia Verruciformis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology; D013945:Thymoma / Q000150:complications* / Q000473:pathology