title: Polymyositis with plasma cell infiltrate in essential mixed cryoglobulinaemia.
abstract: A patient with essential cryoglobulinaemia who presented with polymyositis is described. Muscle biopsy showed intense plasma cell infiltration of muscle. Plasmapheresis produced a rapid resolution of the cutaneous manifestations of the disease, but little improvement in muscle strength. Oral steroids resulted in moderate improvement in muscle strength. There have been no previously reported cases of polymyositis in association with essential cryoglobulinaemia.
authors.affiliation: University of Saskatchewan, Royal University Hospital, Saskatoon, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Voll
authors.forename: L C
authors.initials: LC
authors.lastname: Ang
authors.forename: J
authors.initials: J
authors.lastname: Sibley
authors.forename: R
authors.initials: R
authors.lastname: Card
authors.forename: K
authors.initials: K
authors.lastname: Lefevre
mesh_terms: D000284:Administration, Oral; D000368:Aged; D001706:Biopsy; D003449:Cryoglobulinemia / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology; D009132:Muscles / Q000473:pathology*; D009460:Neurologic Examination; D010950:Plasma Cells / Q000473:pathology*; D010956:Plasmapheresis; D017285:Polymyositis / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011241:Prednisone / Q000008:administration & dosage
chemical_list: D011241:Prednisone