Autoantibodies to nuclear mitotic apparatus in a patient with vitiligo and autoimmune thyroiditis.
Circulating autoantibodies against the nuclear mitotic apparatus (NuMA) protein have been detected in sera of patients with a variety of connective tissue diseases. A close relation of anti-NuMA antibodies to define subsets of these diseases could not be established. This is the first description of a patient with vitiligo, autoimmune thyroiditis and a high titer of antibodies against NuMA on Hep-2 cells. The possibility of a beginning of multiple autoimmune syndrome cannot be excluded.
Auer-Grumbach
P
P
Department of Dermatology, University of Graz, Austria.
Stangl
M
M
D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D006801:Humans; D008941:Spindle Apparatus / Q000276:immunology*; D013967:Thyroiditis, Autoimmune / Q000276:immunology*; D014820:Vitiligo / Q000276:immunology*
D001323:Autoantibodies