Sequence analysis of the nucleocapsid protein gene of rat coronavirus SDAV-681.
The nucleotide sequence of the 3'-end of the genomic RNA of sialodacryoadenitis virus strain 681 (SDAV-681) was determined. A large open reading frame encoding a 454-amino-acid protein was identified as the nucleocapsid protein (N) gene, since the predicted protein is similar in size, chemical properties, and amino acid sequence to the N proteins of other coronaviruses. The amino acid variance of the N proteins between SDAV and mouse hepatitis virus (MHV) is not markedly different from that among MHV strains. A high degree of genetic relatedness between SDAV and MHV was revealed in the intergenic and 3'-noncoding sequences as well as in the N gene.
Kunita
S
S
Department of Laboratory Animal Science, School of Hygienic Sciences, Kitasato University, Sagamihara, Japan.
Mori
M
M
Terada
E
E
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002213:Capsid / Q000235:genetics*; D003332:Coronaviridae / Q000235:genetics*; D016679:Genome, Viral; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics; D051381:Rats; D017386:Sequence Homology, Amino Acid; D014758:Viral Core Proteins / Q000235:genetics*
D014758:Viral Core Proteins