Unusual kinetic behavior predicted for alpha-keto acid dehydrogenase complexes.
A novel regulation type, which may be observed as an unusual kinetic 'cooperativity', is predicted for the alpha-keto acid dehydrogenase complexes. The inter-relationship of this regulation with the well-known regulatory effect of enzyme phosphorylation is discussed.
Goldstein
B N
BN
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow region.
Selivanov
V A
VA
D000818:Animals; D007700:Kinetics; D008322:Mammals; D008962:Models, Theoretical; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism*; D011773:Pyruvates / Q000378:metabolism
D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates