title: Disseminated atypical blastomycosis in two patients with AIDS.
abstract: Two men with AIDS developed fungal infections and subsequently died as a result of dissemination of the fungal infection. Findings obtained by histologic examination, serological studies, and cultures suggested that the infections were caused by Blastomyces dermatitidis. Tissue sections showed polymorphic yeast-like cells 5-20 microns in diameter (some with broad and others with narrow single- or multiple-based buds), small yeasts, and hyphal elements. The exoantigen K positivity and exoantigen A negativity of one of the isolates indicated that the fungus was more like an African than a North American serotype.
authors.affiliation: Department of Pathology, University of California, Irvine, Orange 92668.
authors.forename: G
authors.initials: G
authors.lastname: Tan
authors.forename: L
authors.initials: L
authors.lastname: Kaufman
authors.forename: E M
authors.initials: EM
authors.lastname: Peterson
authors.forename: L M
authors.initials: LM
authors.lastname: de la Maza
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D000946:Antigens, Fungal / Q000032:analysis; D001758:Blastomyces / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D001759:Blastomycosis / Q000382:microbiology*; D006801:Humans; D008168:Lung / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000382:microbiology; D008297:Male
chemical_list: D000946:Antigens, Fungal