title: [Primary adrenal carcinoma].
abstract: A series of 17 patients with primary adrenal cortical carcinoma is presented. Of 14 patients without evidence of disseminated disease prior to radical surgery, 6 developed distant metastases during follow-up. The mean interval free of disease in these patients was 12 months (range 3-40) and the median survival 15 months. Of the six patients in whom adjuvant external beam radiotherapy was delivered, no evidence of local recurrence was observed. Of the patients treated without external beam radiotherapy, 3 local failures were observed. The projected 5 years survival was 35%, which is similar to that reported in the literature. To date, there is no evidence that chemotherapy nor radiotherapy could improve the survival, however, radiotherapy might increase the local control in selected cases.
authors.affiliation: Departamento de Urología, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra, Pamplona.
authors.forename: F
authors.initials: F
authors.lastname: de Castro
authors.forename: W
authors.initials: W
authors.lastname: Isa
authors.forename: L
authors.initials: L
authors.lastname: Agüera
authors.forename: D
authors.initials: D
authors.lastname: Rosell Costa
authors.forename: J I
authors.initials: JI
authors.lastname: Abad
authors.forename: J E
authors.initials: JE
authors.lastname: Robles
authors.forename: J J
authors.initials: JJ
authors.lastname: Zudaire
authors.forename: J M
authors.initials: JM
authors.lastname: Berián
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D000315:Adrenalectomy; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011182:Postoperative Care; D011882:Radiotherapy, High-Energy; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome