Human interleukin-2-IgM heavy-chain-fusion proteins are cytotoxic for cells expressing the IL2 receptor.
Vie
H
H
Institut National pour la Santé et la Recherche Médicale (INSERM U.211), Nantes, France.
Gauthier
T
T
Breathnach
R
R
Bonneville
M
M
Godard
A
A
Dietrich
J
J
Karam
G
G
Gesnel
M C
MC
Peyrat
M A
MA
Jacques
Y
Y
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D007075:Immunoglobulin M / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D007376:Interleukin-2 / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D015375:Receptors, Interleukin-2 / Q000187:drug effects / Q000378:metabolism*; D011993:Recombinant Fusion Proteins / Q000378:metabolism / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014162:Transfection; D014407:Tumor Cells, Cultured
D007143:Immunoglobulin Heavy Chains; D007075:Immunoglobulin M; D007376:Interleukin-2; D015375:Receptors, Interleukin-2; D011993:Recombinant Fusion Proteins