The role of marine fish oils in the treatment of ulcerative colitis.
Recent studies suggest that marine fish-oil supplements, which are rich in n-3 fatty acids, may reduce the inflammation associated with ulcerative colitis. Fish oils may exert their beneficial effects by shifting eicosanoid synthesis to less inflammatory species or by modulating tissue levels of certain cytokines.
Ross
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Department of Internal Medicine, Tufts University School of Medicine, Boston, MA 02111.
D003093:Colitis, Ulcerative / Q000188:drug therapy*; D016207:Cytokines / Q000378:metabolism; D015777:Eicosanoids / Q000378:metabolism; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use; D005395:Fish Oils / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism
D016207:Cytokines; D015777:Eicosanoids; D015525:Fatty Acids, Omega-3; D005395:Fish Oils