title: Improvement of yellow nail syndrome with oral zinc supplementation.
abstract: An unusual case of yellow nail syndrome (YNS) is reported. Total resolution of yellow nails and lymphoedema was observed following oral zinc supplementation for 2 years. A few years later, the patient developed a classical seropositive rheumatoid arthritis (RA). YNS, alone or associated with RA remains a rare clinical condition. The reported beneficial effects of zinc supplementation in YNS, as well as in several other pathological conditions, raise interest about the role of this trace element and its potential therapeutic implications and suggest further investigations are necessary.
authors.affiliation: Department of Rheumatology, St Vincent's Hospital, Sydney, NSW, Australia.
authors.forename: J F
authors.initials: JF
authors.lastname: Arroyo
authors.forename: M L
authors.initials: ML
authors.lastname: Cohen
mesh_terms: D000284:Administration, Oral; D000328:Adult; D005260:Female; D006801:Humans; D008209:Lymphedema / Q000150:complications / Q000188:drug therapy*; D009260:Nail Diseases / Q000150:complications / Q000188:drug therapy*; D010859:Pigmentation Disorders / Q000150:complications / Q000188:drug therapy*; D013577:Syndrome; D015032:Zinc / Q000008:administration & dosage*
chemical_list: D015032:Zinc