title: Examination of the effects of hemodynamic and pharmacologic interventions on coronary collateral flow in a patient during cardiac catheterization.
abstract: The vasomotor response of native human collateral vessels to pharmacologic or hemodynamic vasodilatory stimuli is not well known. We describe a case where retrograde collateral flow velocity was measured both at baseline and following selected hemodynamic and pharmacologic interventions. This index case represents the first in a series of potential human physiologic studies designed to address questions pertaining to control of collateral blood supply in humans.
authors.affiliation: Cardiology Division, St. Louis University Hospital, Missouri.
authors.forename: T
authors.initials: T
authors.lastname: Donohue
authors.forename: M J
authors.initials: MJ
authors.lastname: Kern
authors.forename: R
authors.initials: R
authors.lastname: Bach
authors.forename: F
authors.initials: F
authors.lastname: Aguirre
authors.forename: T
authors.initials: T
authors.lastname: Wolford
mesh_terms: D000241:Adenosine; D015906:Angioplasty, Balloon, Coronary; D001783:Blood Flow Velocity / Q000502:physiology; D006328:Cardiac Catheterization; D003097:Collateral Circulation / Q000502:physiology*; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D003331:Coronary Vessels / Q000187:drug effects / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin; D014666:Vasomotor System / Q000187:drug effects / Q000502:physiology
chemical_list: D005996:Nitroglycerin; D000241:Adenosine