title: [Malignant lymphomas with first manifestation in the spine as a rare differential diagnosis of lumbar intervertebral disk syndrome].
abstract: Spinal epidural lymphoma need rarely be considered as a cause of lumbar nerve root compression. We report on two patients suffering from malignant epidural non-Hodgkin lymphoma, admitted with clinical and radiological signs of a lumbar herniated disc. Non-Hodgkin lymphoma can affect the spinal cord and nerve roots rarely as an isolated epidural spinal infiltration in the absence of widespread disease or - as in our two cases - as the first feature of disseminated systemic disease. Epidural non-Hodgkin lymphoma with neurological deficits should be treated by early decompressive (hemi-)laminectomy, postoperative radiotherapy and chemotherapy.
authors.affiliation: Neurochirurgische Abteilung des Knappschafts-Krankenhauses, Bergmannsheil, Gelsenkirchen-Buer.
authors.forename: F J
authors.initials: FJ
authors.lastname: Prestar
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008297:Male; D009192:Myelography; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed