Acute renal failure in theophylline poisoning.
A 57-yr-old woman with an intentional theophylline overdose complicated by rhabdomyolysis, renal failure and microangiopathic haemolytic anaemia is reported. Severe renal vasoconstriction, myoglobinuria and antagonism of adenosine are considered to be the principal pathophysiological renal mechanisms involved.
ter Maaten
J C
JC
Department of Internal Medicine, Catharina Hospital, Eindhoven, Netherlands.
Hoorntje
S J
SJ
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000743:Anemia, Hemolytic / Q000139:chemically induced; D062787:Drug Overdose; D005260:Female; D006801:Humans; D008875:Middle Aged; D012206:Rhabdomyolysis / Q000139:chemically induced; D013806:Theophylline / Q000506:poisoning*
D013806:Theophylline