title: Hearing loss and vestibular dysfunction in childhood from the use of streptomycin in Albania.
abstract: With the entry of a large number of Albanians in the area of Epirus over the past 8 months, a significant number of children with hearing problems or deafness has been examined in the out patient ward of the University Hospital of Ioannina. From the Pediatric-Neurologic-Psychiatric and Otorhinolaryngologic examination of these children, 18 cases with hearing problems and vestibular dysfunction due to administration of streptomycin sulfate have been defined. This article reports the ototoxic drug which has been used and is still being used in Albania, the procedure of audiological and vestibular investigation, and the damage which has been evoked in the auditory and vestibular pathway of the children in whom it has been administered.
authors.affiliation: Department of Otorhinolaryngology, Medical School, University of Ioannina, Greece.
authors.forename: J
authors.initials: J
authors.lastname: Kastanioudakis
authors.forename: A
authors.initials: A
authors.lastname: Skevas
authors.forename: D
authors.initials: D
authors.lastname: Assimakopoulos
authors.forename: D
authors.initials: D
authors.lastname: Anastasopoulos
mesh_terms: D000158:Acoustic Impedance Tests; D000415:Albania / Q000453:epidemiology; D001300:Audiometry, Evoked Response; D002150:Caloric Tests; D002648:Child; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D009760:Nystagmus, Physiologic; D012022:Reflex, Acoustic / Q000187:drug effects; D013307:Streptomycin / Q000009:adverse effects*; D015837:Vestibular Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology
chemical_list: D013307:Streptomycin