Glucose tolerance factor reduces blood glucose and free fatty acids levels in diabetic rats.
Effect of Glucose Tolerance Factor (GTF) extracted from commercially available yeast extract powder was examined on streptozotocin diabetic rats. Different doses of GTF preparation were injected into diabetic rats, with no addition of exogenous insulin. Within two hours there was a significant decrease both in blood glucose and free fatty acids (FFA) levels in the diabetic animals, indicating an anti-diabetic potential of GTF.
Mirsky
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Department of Biology, Oranim, University of Haifa, Tivon, Israel.
D000596:Amino Acids / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D002857:Chromium / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D007700:Kinetics; D008297:Male; D009539:Nicotinic Acids / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017207:Rats, Sprague-Dawley
D000596:Amino Acids; D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D009539:Nicotinic Acids; C015240:glucose tolerance factor; D002857:Chromium