title: Acute renal failure due to tubular necrosis caused by wildfowl-mediated hemlock poisoning.
abstract: We report the clinical and histological findings in patients with acute renal failure caused by the ingestion of wildfowl who had eaten hemlock buds. Neurotoxic effects were accompanied by rhabdomyolysis, myoglobinuria, and acute tubular necrosis. Histological studies showed diffuse degeneration of the tubular epithelium. Immunohistological studies demonstrated the presence of myoglobin and actin in renal tubular cells.
authors.affiliation: Department of Nephrology, Regional Hospital, Taranto, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Scatizzi
authors.forename: A
authors.initials: A
authors.lastname: Di Maggio
authors.forename: D
authors.initials: D
authors.lastname: Rizzi
authors.forename: A M
authors.initials: AM
authors.lastname: Sebastio
authors.forename: C
authors.initials: C
authors.lastname: Basile
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000470:Alkaloids / Q000506:poisoning*; D000818:Animals; D001717:Birds; D006801:Humans; D007668:Kidney / Q000473:pathology; D007683:Kidney Tubular Necrosis, Acute / Q000209:etiology* / Q000473:pathology; D010880:Piperidines; D010939:Plant Poisoning / Q000150:complications / Q000209:etiology*
chemical_list: D000470:Alkaloids; D010880:Piperidines; C007112:coniine