Strategies for the treatment of pneumoconiosis.
Regulatory control of dust in the workplace has greatly reduced the development of pneumoconiosis, yet the prevention of silicosis and coal workers' pneumoconiosis has not been accomplished. Cases of pneumoconiosis continue to occur, and there is no proven way to affect the natural history of these progressive inflammatory and fibrotic processes. Although pneumoconiosis and silicosis are considered untreatable in Western countries, in China an aggressive search has been underway for therapeutic agents and clinical procedures to treat these diseases. The important aspects are reviewed for the tried therapies, including corticosteroids, aluminum citrate complex, PVNO, tetrandrine, xinin, and whole lung lavage.
Banks
D E
DE
Section of Pulmonary and Critical Care Medicine, School of Medicine, West Virginia University, Morgantown.
Cheng
Y H
YH
Weber
S L
SL
Ma
J K
JK
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000470:Alkaloids / Q000627:therapeutic use*; D044182:Benzylisoquinolines; D002951:Citrates / Q000627:therapeutic use*; D019343:Citric Acid; D006801:Humans; D011009:Pneumoconiosis / Q000628:therapy*; D012829:Silicosis / Q000628:therapy; D007507:Therapeutic Irrigation
D000305:Adrenal Cortex Hormones; D000470:Alkaloids; D044182:Benzylisoquinolines; D002951:Citrates; D019343:Citric Acid; C009438:tetrandrine