Alveolar haemorrhage as a presenting feature of myeloma.
An immunoglobulin A (IgA)-paraprotein secreting myeloma was found to be the underlying disease in a patient who presented with alveolar haemorrhage. The diffuse pulmonary bleeding stopped after initiation of treatment consisting of corticosteroids and melphalan. A paraprotein mediated lesion of the alveolar capillary membrane was suspected but could not be demonstrated.
Russi
E
E
Dept of Medicine, University Hospital of Zurich, Switzerland.
Odermatt
B
B
Joller-Jemelka
H I
HI
Spycher
M A
MA
D001706:Biopsy; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis; D011650:Pulmonary Alveoli / Q000473:pathology*; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed