Interaction between human immunodeficiency virus and Toxoplasma gondii replication in dually infected monocytoid cells.
THP-1 monocytoid cells, either not infected or chronically infected with human immunodeficiency virus type 1 (HIV-1), were challenged with Toxoplasma gondii. Parasitic growth, as assessed by trophozoite counting and measurement of supernatant p30 membrane antigen, was similar in HIV-infected and noninfected THP-1 cells. Also, T. gondii did not affect HIV replication. These experiments therefore failed to demonstrate any interaction between HIV-1 and T. gondii replication in concurrently infected monocytoid cells.
Welker
Y
Y
Laboratory of Parasitology, Saint-Louis Hospital, Paris, France.
Molina
J M
JM
Poirot
C
C
Ferchal
F
F
Decazes
J M
JM
Lagrange
P
P
Derouin
F
F
D000818:Animals; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1 / Q000254:growth & development*; D006801:Humans; D009000:Monocytes / Q000382:microbiology*; D014122:Toxoplasma / Q000254:growth & development*; D014123:Toxoplasmosis / Q000150:complications*; D014407:Tumor Cells, Cultured; D014779:Virus Replication