title: Generalized medullary infarction of the long bones in a horse.
abstract: Generalized medullary infarction of the long bones was diagnosed in a 12-year-old Tennessee Walking Horse mare. The mare was referred after a 6-week course of shifting weight on her hind limbs, and kicking. Physical examination revealed mild stifle joint distention and withdrawal reactions to digital pressure over the long bones. Radiography revealed patchy areas of medullary sclerosis in the distal portion of each femur and proximal portion of each tibia. A full-thickness cortical and cancellous tibial biopsy revealed infarcted bone marrow, with cortical and periosteal osteonecrosis. The cause of the intramedullary infarction could not be determined, but might have been attributable to cumulative bone stress resulting from mild primary hyperparathyroidism and some unidentified inflammatory factor.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210.
authors.forename: C K
authors.initials: CK
authors.lastname: Fenger
authors.forename: J J
authors.initials: JJ
authors.lastname: Bertone
authors.forename: D
authors.initials: D
authors.lastname: Biller
authors.forename: J
authors.initials: J
authors.lastname: Merryman
mesh_terms: D000818:Animals; D001706:Biopsy / Q000662:veterinary; D001853:Bone Marrow / Q000098:blood supply* / Q000473:pathology; D005260:Female; D005269:Femur / Q000098:blood supply* / Q000473:pathology; D006734:Horse Diseases / Q000473:pathology; D006736:Horses; D007238:Infarction / Q000662:veterinary*; D010020:Osteonecrosis / Q000473:pathology / Q000662:veterinary; D013977:Tibia / Q000098:blood supply* / Q000473:pathology