title: Fluoride acquisition on and in fluorotic human enamel after topical application in vitro.
abstract: The uptake of alkali soluble and alkali insoluble fluoride on and in fluorotic enamel was investigated in vitro. Teeth from Kenya, assigned score 3 in accordance with Thylstrup-Fejerskov's fluorosis index, were used. The enamel was treated with either a neutral 2% NaF solution, a 0.2% NaF solution (pH 5.5), or the supernatant from a 0.1% NaF-containing toothpaste (pH 7). The treatment time was 1 h. The reaction product formed on the enamel was analyzed by KOH extraction and acid etching. Significantly higher amounts of alkali soluble fluoride were formed on the enamel from the 2% and 0.2% NaF solutions, as compared with the control. There was also a significant increase in the firmly bound fluoride after treatment with the neutral 2% NaF solution.
authors.affiliation: Department of Preventive Dentistry, Faculty of Dentistry, State University of Rio de Janeiro, Brazil.
authors.forename: R
authors.initials: R
authors.lastname: Cruz
authors.forename: P M
authors.initials: PM
authors.lastname: Ng'ang'a
authors.forename: B
authors.initials: B
authors.lastname: Ogaard
authors.forename: J
authors.initials: J
authors.lastname: Valderhaug
mesh_terms: D000704:Analysis of Variance; D002124:Calcium Fluoride; D003743:Dental Enamel / Q000378:metabolism* / Q000648:ultrastructure; D003745:Dental Enamel Permeability; D009050:Fluorosis, Dental / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012969:Sodium Fluoride / Q000493:pharmacokinetics*
chemical_list: D012969:Sodium Fluoride; D002124:Calcium Fluoride