title: Epithelioid hemangioendothelioma with osteoclastlike giant cells.
abstract: This article describes histopathologic and immunohistologic features of an epithelioid hemangioendothelioma that presented in the neck of a 40-year-old man. This tumor was unusual because of the presence of osteoclastlike giant cells scattered throughout the entire lesion. The tumor cells reacted positively for factor VIII-related antigen, and the osteoclastlike giant cells were reactive for KP1 antibody, a macrophage-associated antigen. We are aware of only one other previously reported example of soft-tissue epithelioid hemangioendothelioma with an abundance of osteoclast-like giant cells.
authors.affiliation: Department of Oral Pathology, Armed Forces Institute of Pathology, Washington, DC 20306.
authors.forename: S B
authors.initials: SB
authors.lastname: Williams
authors.forename: B C
authors.initials: BC
authors.lastname: Butler
authors.forename: F W
authors.initials: FW
authors.lastname: Gilkey
authors.forename: S B
authors.initials: SB
authors.lastname: Kapadia
authors.forename: D M
authors.initials: DM
authors.lastname: Burton
mesh_terms: D000328:Adult; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006390:Hemangioendothelioma / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010010:Osteoclasts / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology*