title: Hysteroscopic metroplasty in the diethylstilbestrol-exposed uterus and similar nonfusion anomalies: effects on subsequent reproductive performance; a preliminary report.
abstract: OBJECTIVE
  To determine the feasibility of correcting the uterine abnormalities seen in diethylstilbestrol (DES)-exposed women and similar anomalies.
  
  
  METHODS
  Patients served as their own controls.
  
  
  METHODS
  University based and private practice tertiary referral practice.
  
  
  METHODS
  Eight patients referred for infertility, recurrent pregnancy loss, or both with an abnormal uterine contour as seen by hysterosalpingogram.
  
  
  METHODS
  Hysteroscopic metroplasty.
  
  
  METHODS
  Ability to conceive and carry pregnancy to livebirth.
  
  
  RESULTS
  Three of five patients with secondary infertility and recurrent pregnancy losses had livebirths as did a patient with secondary infertility. Two patients with primary infertility failed to conceive.
  
  
  CONCLUSIONS
  Metroplasty may decrease pregnancy loss in these patients but may not enhance fertility.
authors.affiliation: Department of Obstetrics and Gynecology, University of Minnesota, Minneapolis.
authors.forename: T C
authors.initials: TC
authors.lastname: Nagel
authors.forename: J W
authors.initials: JW
authors.lastname: Malo
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D005298:Fertility; D006801:Humans; D015907:Hysteroscopy; D011247:Pregnancy; D011256:Pregnancy Outcome; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery*
chemical_list: D004054:Diethylstilbestrol