title: Double cardiomyopathy: coexistent cardiac amyloidosis and hypertrophic obstructive cardiomyopathy.
abstract: A combination of hypertrophic obstructive cardiomyopathy (HOCM) and cardiac amyloidosis in the same patient is very rare. Clinical diagnosis could be extremely difficult and may require myocardial biopsy. We are reporting a patient with this combination who was referred to our institution because of features of HOCM based on clinical, echocardiographic and Doppler criteria. Cardiac amyloidosis was only recognized after myocardial biopsy that failed to reveal evidence of HOCM. Only after the patient expired from severe, intractable heart failure did the autopsy findings confirm the association of HOCM. We believe that the combination of the two cardiomyopathic processes is very rare and makes treatment extremely difficult.
authors.affiliation: Department of Medicine, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157.
authors.forename: W P
authors.initials: WP
authors.lastname: Buchanan
authors.forename: S W
authors.initials: SW
authors.lastname: Schreiter
authors.forename: F R
authors.initials: FR
authors.lastname: Kahl
authors.forename: P E
authors.initials: PE
authors.lastname: Lantz
authors.forename: H B
authors.initials: HB
authors.lastname: Cheek
authors.forename: J
authors.initials: J
authors.lastname: Risley
authors.forename: A M
authors.initials: AM
authors.lastname: Nomeir
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D009202:Cardiomyopathies / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D004452:Echocardiography; D005260:Female; D006801:Humans