title: Inhibition of the scarlet fever exanthem in concurrent varicella and group A streptococcus infection.
abstract: An atypical scarlet fever exanthem was noted in a 5-year-old child with varicella complicated by secondary group A beta-hemolytic streptococcus pneumonia and empyema. The rash consisted of symmetrical, concentric, circular exanthem-free zones surrounding individual varicella vesicles. The possible role of virus-induced interferon in locally modifying the effect of streptococcal pyrogenic exotoxin is explored.
authors.affiliation: Department of Pediatrics, Thomas Jefferson University School of Medicine, Philadelphia, Pennsylvania.
authors.forename: M A
authors.initials: MA
authors.lastname: Friedman
authors.forename: J D
authors.initials: JD
authors.lastname: Klein
authors.forename: S C
authors.initials: SC
authors.lastname: Eppes
mesh_terms: D002644:Chickenpox / Q000150:complications* / Q000473:pathology; D002675:Child, Preschool; D006801:Humans; D008297:Male; D012541:Scarlet Fever / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology; D013290:Streptococcal Infections / Q000150:complications*; D013297:Streptococcus pyogenes