title: Trisomy 21 presented as a transient unilateral pleural effusion at 18 weeks' gestation.
abstract: We describe a rare case in which a unilateral fetal pleural effusion was noted at 18 weeks' gestation with subsequent spontaneous resolution occurring 1 week later. Amniocentesis revealed a trisomy 21 karyotype. Chromosomal analysis may be indicated in cases in which accumulation of fluid in fetal serous cavities has spontaneously resolved.
authors.affiliation: Department of Obstetrics and Gynecology, Strong Memorial Hospital, University of Rochester School of Medicine and Dentistry, NY 14642-8668.
authors.forename: D M
authors.initials: DM
authors.lastname: Sherer
authors.forename: J S
authors.initials: JS
authors.lastname: Abramowicz
authors.forename: S R
authors.initials: SR
authors.lastname: Sanko
authors.forename: J R
authors.initials: JR
authors.lastname: Woods
mesh_terms: D000328:Adult; D000649:Amniocentesis; D004314:Down Syndrome / Q000175:diagnosis*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000235:genetics*; D005865:Gestational Age; D006801:Humans; D007621:Karyotyping; D010996:Pleural Effusion / Q000000981:diagnostic imaging / Q000235:genetics*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal