Influence of stress on IgE production.
Intense acute stress, consequent to restraint, leads to a diminished production of IgE antiovalbumin antibodies in mice. The IgE content of sera from experimental or control animals was assayed by the enzyme-linked immunosorbent assay (ELISA) at days 8, 16, and 20 after immunization. The statistics revealed significant differences in the IgE level of the animals submitted to acute stress and home cage control animals on days 16 and 20 after immunization, but not on day 8.
Loureiro
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Immunology Research and Training Center O. G. Bier, Butantan Institute, São Paulo, Brasil.
Wada
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CY
D000707:Anaphylaxis / Q000276:immunology; D000818:Animals; D001143:Arousal / Q000502:physiology*; D007108:Immune Tolerance / Q000276:immunology; D007073:Immunoglobulin E / Q000096:biosynthesis*; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D010047:Ovalbumin / Q000276:immunology; D012931:Social Environment; D013312:Stress, Physiological / Q000276:immunology*
D007073:Immunoglobulin E; D010047:Ovalbumin