title: Biology and behavior. A set-point hypothesis of psychological functioning.
abstract: This article provides a broad overview of an exploratory thesis designed to enhance an understanding of perturbations and rigidities of psychological functioning--a set-point hypothesis of psychological functioning. Historical precedents and parallels with Keesey's set-point theory of obesity are offered. Basic tenets of the hypothesis are detailed, and relevance to clinical behavioral theory is outlined. It is concluded that the set-point hypothesis may provide a framework for conceptualizing clinical cases and optimizing interventions. The thesis appears to be testable; however, the articulation of specific methodologies and research designs must be undertaken before the ultimate usefulness of the set-point hypothesis can be determined.
authors.affiliation: Section of Psychology, Mayo Clinic, Rochester, NY 55905.
authors.forename: D E
authors.initials: DE
authors.lastname: Williams
authors.forename: J K
authors.initials: JK
authors.lastname: Thompson
mesh_terms: D000223:Adaptation, Psychological / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D006801:Humans; D007206:Individuality; D010551:Personality / Q000502:physiology*; D011603:Psychophysiology; D012931:Social Environment