title: Reassessment of the clinical significance of periodic lateralized epileptiform discharges in pediatric patients.
abstract: A review of clinical data from 18 pediatric patients with periodic lateralized epileptiform discharges and bilateral independent periodic lateralized epileptiform discharges (PLEDs and BIPLEDs) showed 2 with chronic neurologic illness, 6 with a history of prior seizures, 14 with depressed sensorium at the time of EEG, 5 deaths, and 8 of 13 survivors with neurologic deficits. These findings are similar to the combined data from reports involving adult patients only. Separating pediatric patients with PLEDs from those with BIPLEDs shows some influence from patients with BIPLEDs. Overall, our data do not suggest significant clinical differences for PLEDs between children and adults.
authors.affiliation: Department of Neurology, University of Texas Southwestern Medical Center, Dallas 75235.
authors.forename: H G
authors.initials: HG
authors.lastname: Raroque
authors.forename: W
authors.initials: W
authors.lastname: Wagner
authors.forename: P C
authors.initials: PC
authors.lastname: Gonzales
authors.forename: R F
authors.initials: RF
authors.lastname: Leroy
authors.forename: D
authors.initials: D
authors.lastname: Karnaze
authors.forename: A R
authors.initials: AR
authors.lastname: Riela
authors.forename: E S
authors.initials: ES
authors.lastname: Roach
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001927:Brain Diseases / Q000150:complications; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies