title: Control of established Salmonella typhimurium intestinal colonization with in vivo-passaged anaerobes.
abstract: Broiler chickens were inoculated orally with 10(6) Salmonella typhimurium on the day of hatch. Twenty-four to 72 hr after challenge, the chicks were inoculated orally with cecal microflora that had been repeatedly passed through lactose-fed broiler chicks. In vivo passage proved to be a convenient and practical method for preserving protective anaerobic flora. These organisms effectively reduced S. typhimurium concentrations in the cecal contents by 4-5 orders of magnitude, even when given 24 to 72 hr after Salmonella challenge inoculation.
authors.affiliation: Food Animal Protection Research Unit, U.S. Department of Agriculture, College Station, Texas 77845.
authors.forename: R L
authors.initials: RL
authors.lastname: Ziprin
authors.forename: D E
authors.initials: DE
authors.lastname: Corrier
authors.forename: J R
authors.initials: JR
authors.lastname: DeLoach
mesh_terms: D000818:Animals; D001421:Bacteria, Anaerobic / Q000254:growth & development*; D002432:Cecum / Q000382:microbiology*; D002645:Chickens / Q000382:microbiology*; D007785:Lactose / Q000494:pharmacology; D008297:Male; D011201:Poultry Diseases / Q000382:microbiology / Q000517:prevention & control*; D012481:Salmonella Infections, Animal / Q000517:prevention & control*; D012486:Salmonella typhimurium / Q000254:growth & development*; D012692:Serial Passage / Q000662:veterinary
chemical_list: D007785:Lactose