Aversive reactions and alcohol use in Europeans.
Two hundred subjects of European descent completed a questionnaire about alcohol use and reactions to alcohol. Eleven subjects (5.5%) reported that they always experienced unpleasant reactions after small amounts of alcohol, and these subjects reported significantly lower levels for quantity and frequency of habitual alcohol use, and fewer drinks in the preceding 7 days, than the other subjects. Reactions to alcohol, either genetic or acquired, can therefore be significant in determining alcohol use in non-Asian groups.
Whitfield
J B
JB
Department of Clinical Biochemistry, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Martin
N G
NG
D000079:Acetaldehyde / Q000493:pharmacokinetics; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000235:genetics; D000444:Aldehyde Dehydrogenase / Q000172:deficiency; D003431:Cross-Cultural Comparison; D004200:Diseases in Twins / Q000235:genetics; D000431:Ethanol / Q000493:pharmacokinetics; D005060:Europe; D005260:Female; D005483:Flushing / Q000209:etiology* / Q000235:genetics; D006801:Humans; D007527:Isoenzymes / Q000172:deficiency; D008297:Male
D007527:Isoenzymes; D000431:Ethanol; D000444:Aldehyde Dehydrogenase; D000079:Acetaldehyde