title: Mitochondrial activity is required for the expression of IME1, a regulator of meiosis in yeast.
abstract: Sporulation in the yeast Saccharomyces cerevisiae occurs in diploid cells following starvation for glucose and nitrogen sources. A key gene in the regulation of the meiotic process is IME1. A well-documented fact is that respiration is necessary for sporulation. We now show that respiration is necessary for the expression of IME1. We suggest that glucose repression of meiosis is transduced through its effect on respiration, in a pathway separate from that of adenylyl cyclase.
authors.affiliation: Department of Genetics, Hebrew University, Jerusalem, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Treinin
authors.forename: G
authors.initials: G
authors.lastname: Simchen
mesh_terms: D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D005809:Genes, Regulator; D005947:Glucose / Q000378:metabolism; D008540:Meiosis; D008928:Mitochondria / Q000502:physiology*; D010101:Oxygen Consumption; D012331:RNA, Fungal / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D013172:Spores, Fungal
chemical_list: D012331:RNA, Fungal; D012333:RNA, Messenger; D005947:Glucose