Neurosarcoidosis with unusual MRI findings.
This 53-year-old white male presented with a 4-month-history of weakness and pain. Despite an initial partial response to steroid therapy, his neurologic deterioration progressed culminating in paraparesis, paresthesias, urinary incontinence, altered mentation and a 20 lb weight loss. A gadolinium-enhanced MRI study showed a pattern suggestive of perivascular involvement. A subsequent cerebral biopsy was diagnostic for neurosarcoidosis.
Handler
M S
MS
Department of Pathology and Oncology, University of Kansas Medical Center, Kansas City.
Johnson
L M
LM
Dick
A R
AR
Batnitzky
S
S
D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis* / Q000473:pathology