Epithelioid hemangioendothelioma with osteoclastlike giant cells.
This article describes histopathologic and immunohistologic features of an epithelioid hemangioendothelioma that presented in the neck of a 40-year-old man. This tumor was unusual because of the presence of osteoclastlike giant cells scattered throughout the entire lesion. The tumor cells reacted positively for factor VIII-related antigen, and the osteoclastlike giant cells were reactive for KP1 antibody, a macrophage-associated antigen. We are aware of only one other previously reported example of soft-tissue epithelioid hemangioendothelioma with an abundance of osteoclast-like giant cells.
Williams
S B
SB
Department of Oral Pathology, Armed Forces Institute of Pathology, Washington, DC 20306.
Butler
B C
BC
Gilkey
F W
FW
Kapadia
S B
SB
Burton
D M
DM
D000328:Adult; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006390:Hemangioendothelioma / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010010:Osteoclasts / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology*