[Hereditary diseases and abnormalities as cause of death during the first 2 years of life among 7 groups of Oslo children. A comparison between Norwegian and Pakistani children].
Perinatal and infant death are important indicators of community health. We examined the rate of stillbirth and death before the age of two years among 36,700 children with Norwegian and 2,750 children with Pakistani background. There was no difference in the rate of stillbirth and death during the second year of life, but a 2.5-3 times higher death rate during the first year of life among the Pakistani children, compared with the Norwegian children. When deaths due to single gene disorders and congenital malformations were excluded, the death rate during the first year of life was similar in the two groups. The Pakistani children had an 18 times higher death rate from autosomal recessive disorders and a ten times higher death rate from malformations of the central nervous system. The difference in death rate between the two groups was probably due to the high rate of consanguinity among the Pakistani parents.
Steen
J
J
Barneavdelingen, Familie-barn klinikken, Ullevål sykehus, Oslo.
Lindemann
R
R
Orstavik
K H
KH
D002423:Cause of Death; D002675:Child, Preschool; D000013:Congenital Abnormalities / Q000235:genetics / Q000401:mortality*; D003241:Consanguinity; D005260:Female; D005313:Fetal Death; D030342:Genetic Diseases, Inborn / Q000235:genetics / Q000401:mortality*; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D008297:Male; D009664:Norway / Q000453:epidemiology; D010154:Pakistan / Q000453:epidemiology / Q000208:ethnology; D011247:Pregnancy