title: [Technique and results of hyperthermic perfusion of the extremity in melanoma patients].
abstract: The results of hyperthermic isolated limb perfusion therapy in 36 patients with stage II-IV malignant melanoma of the extremities are presented. With the technique employed, neither severe complications nor functional deficiencies attributable to the perfusion therapy were observed. The findings on follow-up for up to 36 months are comparable to those reported in the literature, with survival rates of about 90% for stage II and III patients and nearly 50% for stage IV patients. Thus, our technique appears to be beneficial, especially in respect of the very low rate of side effects.
authors.affiliation: Abteilung für Allgemeine, Abdominal- und Gefässchirurgie, Universität des Saarlandes, Homburg/Saar.
authors.forename: G
authors.initials: G
authors.lastname: Omlor
authors.forename: F
authors.initials: F
authors.lastname: Bahmer
authors.forename: S
authors.initials: S
authors.lastname: Meessen
authors.forename: D
authors.initials: D
authors.lastname: Zang
authors.forename: G
authors.initials: G
authors.lastname: Feifel
authors.forename: H
authors.initials: H
authors.lastname: Zaun
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007866:Leg / Q000098:blood supply*; D008197:Lymph Node Excision; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D008558:Melphalan / Q000008:administration & dosage; D008875:Middle Aged; D009367:Neoplasm Staging; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
chemical_list: D002945:Cisplatin; D008558:Melphalan