Successful treatment of a desmoid tumor with doxorubicin.
BACKGROUND
Desmoid tumors are the source of significant morbidity and mortality in patients with Gardner syndrome.


METHODS
The authors present a case report and review of the literature.


RESULTS
A young woman with an extensive abdominal desmoid had a prolonged response to doxorubicin after she did not respond to more conventional treatments.


CONCLUSIONS
To the authors' knowledge, this is the first report of the successful treatment of desmoids with doxorubicin used as a single agent. Reports of the efficacy of chemotherapy in these and related tumors are reviewed.
Seiter
K
K
Gastrointestinal Tumor Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
Kemeny
N
N
D000008:Abdominal Neoplasms / Q000188:drug therapy* / Q000209:etiology; D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D004317:Doxorubicin / Q000627:therapeutic use*; D005260:Female; D005350:Fibroma / Q000188:drug therapy* / Q000209:etiology; D005736:Gardner Syndrome / Q000150:complications; D006801:Humans; D007223:Infant; D008875:Middle Aged
D004317:Doxorubicin