Transvaginal ultrasonographic characterization of ovarian masses by means of color flow-directed Doppler measurements and a morphologic scoring system.
OBJECTIVE
The aim of the study was to test the hypothesis that a combination of a previously devised morphologic scoring system and color flow-directed Doppler measurements would afford better discrimination between benign and malignant ovarian masses.


METHODS
The scoring system and color flow-directed Doppler measurements for 115 masses were prospectively analyzed and correlated with histopathologic surgical findings.


RESULTS
In 21 masses (18 patients) no flow was obtained. Seventy-eight masses in 70 patients were benign, and 16 masses in 12 patients were malignant. The mean total score for the benign masses was 6.7 and for the malignant masses 11.7. The resistance index was 0.64 for the benign lesions and 0.39 for the malignant masses (range 0.2 to 0.98). The mean pulsatility index of the benign masses was 1.17 and 0.52 for the malignancies (range 0.2 to 2.6). There were no malignancies in the group with no flow obtained. The sensitivity and specificity of score alone was 94% and 87%, respectively, with a 60% positive predictive value. By means of resistance index or pulsatility index the sensitivity was 94%, the specificity 99%, and the positive predictive value 94%.


CONCLUSIONS
These results suggest that Doppler flow measurements alone and in conjunction with a scoring system help differentiate benign from malignant masses.
Timor-Tritsch
L E
LE
Department of Obstetrics and Gynecology, Sloane Hospital for Women, Columbia-Presbyterian Medical Center, New York, NY 10032.
Lerner
J P
JP
Monteagudo
A
A
Santos
R
R
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D009367:Neoplasm Staging; D010048:Ovarian Cysts; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D010053:Ovary / Q000473:pathology*; D011446:Prospective Studies; D014463:Ultrasonography; D014621:Vagina