In situ hybridisation for decorin mRNA in rabbit synovium during antigen-induced arthritis.
Decorin mRNA was localised primarily in the lining layer of normal rabbit synovium. The distribution changed during the development of antigen-induced arthritis. It became more abundant deeper in the synovium and may be correlated with the progressive increase in the deposition of collagen.
Noble
D P
DP
Kennedy Institute of Rheumatology, Hammersmith, London.
Lewthwaite
J C
JC
Dudhia
J
J
Blake
S
S
Henderson
B
B
Hardingham
T E
TE
D000818:Animals; D001169:Arthritis, Experimental / Q000378:metabolism*; D001345:Autoradiography; D015152:Blotting, Northern; D003094:Collagen / Q000378:metabolism; D058575:Decorin; D016326:Extracellular Matrix Proteins; D005260:Female; D017403:In Situ Hybridization; D011509:Proteoglycans / Q000737:chemistry / Q000378:metabolism*; D015347:RNA Probes; D012333:RNA, Messenger / Q000737:chemistry / Q000378:metabolism*; D011817:Rabbits; D013583:Synovial Membrane / Q000033:anatomy & histology / Q000737:chemistry / Q000378:metabolism*; D014158:Transcription, Genetic
D058575:Decorin; D016326:Extracellular Matrix Proteins; D011509:Proteoglycans; D015347:RNA Probes; D012333:RNA, Messenger; D003094:Collagen