Upper-extremity deep-vein thrombosis: thrombolytic therapy with anistrepalase.
A patient with primary axillary vein thrombosis was treated successfully in the emergency department with a single IV bolus of anistrepalase followed by continuous IV heparin. The patient's symptoms resolved quickly, and a repeat venogram 16 hours later showed near-complete resolution of the venous obstruction. We discuss briefly the role of thrombolytic therapy in the treatment of upper-extremity deep-vein thrombosis and the potential advantages of using anistrepalase.
Pires
L A
LA
Division of Cardiovascular Medicine, University of Massachusetts Medical Center, Worcester.
Jay
G
G
D000328:Adult; D016255:Anistreplase / Q000627:therapeutic use*; D001367:Axillary Vein / Q000000981:diagnostic imaging*; D004630:Emergencies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011859:Radiography; D013927:Thrombosis / Q000188:drug therapy*
D016255:Anistreplase; D006493:Heparin