title: Disruption of the 3' phosphoglycerate kinase (pgk) gene in Aspergillus nidulans.
abstract: We report the isolation of a pgk- mutant strain of Aspergillus nidulans by means of a gene disruption strategy, and demonstrate that the pgk gene is located on chromosome VIII. The pgk- mutant conidiates poorly, will only grow on media supplemented with both a glycolytic and a gluconeogenic carbon source, and is inhibited by hexoses.
authors.affiliation: Department of Genetics, University of Leicester, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Streatfield
authors.forename: C F
authors.initials: CF
authors.lastname: Roberts
mesh_terms: D001233:Aspergillus nidulans / Q000201:enzymology* / Q000235:genetics; D002874:Chromosome Mapping; D015825:Chromosomes, Fungal; D004171:Diploidy; D005800:Genes, Fungal; D005822:Genetic Vectors; D006238:Haploidy; D009154:Mutation; D010408:Penicillium chrysogenum / Q000235:genetics; D010641:Phenotype; D010735:Phosphoglycerate Kinase / Q000235:genetics*; D014170:Transformation, Genetic
chemical_list: D010735:Phosphoglycerate Kinase