title: Inhibition of Escherichia coli chemotaxis by omega-conotoxin, a calcium ion channel blocker.
abstract: Escherichia coli chemotaxis was inhibited by omega-conotoxin, a calcium ion channel blocker. With Tris-EDTA-permeabilized cells, nanomolar levels of omega-conotoxin inhibited chemotaxis without loss of motility. Cells treated with omega-conotoxin swam with a smooth bias, i.e., tumbling was inhibited.
authors.affiliation: Department of Biochemistry, University of Wisconsin-Madison 53706-1569.
authors.forename: L S
authors.initials: LS
authors.lastname: Tisa
authors.forename: B M
authors.initials: BM
authors.lastname: Olivera
authors.forename: J
authors.initials: J
authors.lastname: Adler
mesh_terms: D002121:Calcium Channel Blockers / Q000494:pharmacology*; D002633:Chemotaxis / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects* / Q000502:physiology; D010456:Peptides, Cyclic / Q000494:pharmacology*; D020960:omega-Conotoxins
chemical_list: D002121:Calcium Channel Blockers; D010456:Peptides, Cyclic; D020960:omega-Conotoxins; C053423:Conus magus toxin