Assignment of the mouse tartrate-resistant acid phosphatase gene (Acp5) to chromosome 9.
Tartrate-resistant acid phosphatase is a marker enzyme for osteoclasts, the multinucleated cell responsible for bone resorption. Interspecific somatic whole cell hybrids and karyotypically simple microcell hybrids were used to map the gene encoding tartrate-resistant acid phosphatase (Acp5) to mouse Chromosome 9. Acp5 is therefore a member of a syntenic family of genes that map to human chromosome 19p13.1-p13.3 and mouse Chromosome 9.
Grimes
R
R
Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284.
Reddy
S V
SV
Leach
R J
RJ
Scarcez
T
T
Roodman
G D
GD
Sakaguchi
A Y
AY
Lalley
P A
PA
Windle
J J
JJ
D000135:Acid Phosphatase / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D006224:Cricetinae; D003412:Cricetulus; D004277:DNA, Single-Stranded; D006822:Hybrid Cells; D051379:Mice; D008969:Molecular Sequence Data; D051381:Rats; D013644:Tartrates / Q000494:pharmacology*
D004277:DNA, Single-Stranded; D013644:Tartrates; D000135:Acid Phosphatase; C029768:tartaric acid