title: Predictors of postoperative respiratory complications in premature infants after inguinal herniorrhaphy.
abstract: There is a significant incidence of inguinal hernia in premature infants and the optimal timing of repair is controversial. A high rate of postoperative respiratory complications has been reported in this group. In this study, the records of 47 premature infants (mean gestational age, 30.3 weeks) who underwent herniorrhaphy while still in the neonatal intensive care unit were reviewed in an effort to define those conditions that are independent risk factors for complications. Forty-three percent of infants had complications, including postoperative assisted ventilation (34%), episodes of apnea and/or bradycardia (23%), emesis and cyanosis with first feeding (6%), and requirement for postoperative reintubation (4%). Although low gestational age and postconceptual age at operation, low birth weight for gestational age, and preoperative ventilatory assistance were significantly associated with postoperative complications, only a history of respiratory distress syndrome/bronchopulmonary dysplasia (odds ratio 2.3), a history of patent ductus arteriosus (odds ratio 2.5), and low absolute weight at operation (odds ratio 3.5 for 1,000-g decrease) were independent risk factors for postoperative complication. Despite previous reports citing postconceptual age as the factor having the greatest impact on postoperative complications, these results indicate that a history of respiratory dysfunction and size at operation may be more important predictors of postoperative respiratory dysfunction in preterm infants.
authors.affiliation: Department of Surgery, Yale University School of Medicine, New Haven, CT 06510.
authors.forename: G
authors.initials: G
authors.lastname: Gollin
authors.forename: C
authors.initials: C
authors.lastname: Bell
authors.forename: R
authors.initials: R
authors.lastname: Dubose
authors.forename: R J
authors.initials: RJ
authors.lastname: Touloukian
authors.forename: J H
authors.initials: JH
authors.lastname: Seashore
authors.forename: C W
authors.initials: CW
authors.lastname: Hughes
authors.forename: T H
authors.initials: TH
authors.lastname: Oh
authors.forename: J
authors.initials: J
authors.lastname: Fleming
authors.forename: T
authors.initials: T
authors.lastname: O'Connor
mesh_terms: D000367:Age Factors; D000777:Anesthetics / Q000009:adverse effects; D015897:Comorbidity; D003237:Connecticut / Q000453:epidemiology; D005865:Gestational Age; D006552:Hernia, Inguinal / Q000601:surgery*; D006785:Hospitals, University; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008659:Metabolic Diseases / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D012121:Respiration, Artificial; D012140:Respiratory Tract Diseases / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000777:Anesthetics