Proton MR spectroscopic characteristics of a presumed giant subcortical heterotopia.
A newborn presented with a mass replacing the left cerebral hemisphere. Although the internal signal characteristics of the lesion were suggestive of disorganized gray and white matter, a true neoplasia such as a ganglioglioma could not be totally excluded. Biopsy is not recommended in these cases since the results may be misleading. Proton MR spectroscopy was used; this technique also suggested the hamartomatous nature of the lesion. Based on the clinical course and the imaging features, conservative therapy and observation were undertaken instead of surgery. At 6 months of age, the patient is stable and the lesion is unchanged.
Castillo
M
M
Department of Radiology, University of North Carolina School of Medicine, Chapel Hill 27599.
Kwock
L
L
Scatliff
J
J
Gudeman
S
S
Greenwood
R
R
D001932:Brain Neoplasms / Q000151:congenital / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002828:Choristoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D014057:Tomography, X-Ray Computed