Uterine contamination in the guinea pig following transcervical uterine monofilament insertion.
The effects of transcervical, intrauterine monofilaments on guinea pig uterine microflora were determined. The results indicated that bacteria were transferred to the uterus during the insertion process, although in sham control animals these bacteria were eradicated within 10 days. In the presence of an intrauterine substrate the bacteria within the uterus persisted for up to 6 months. Electron micrographs showed that bacteria were adhered to the monofilament within a biofilm, although some bacteria were planktonic.
Gard
P R
PR
Department of Pharmacy, Brighton Polytechnic, UK.
Malhi
J S
JS
Hanlon
G W
GW
D000818:Animals; D001419:Bacteria / Q000254:growth & development* / Q000648:ultrastructure; D005260:Female; D006168:Guinea Pigs; D007434:Intrauterine Devices / Q000009:adverse effects*; D008855:Microscopy, Electron, Scanning; D000292:Pelvic Inflammatory Disease / Q000209:etiology*; D013997:Time Factors; D014599:Uterus / Q000382:microbiology*