title: MRI in craniofacial fibrous dysplasia.
abstract: Five patients with biopsy-proven craniofacial fibrous dysplasia underwent MRI with T1- and T2-weighted sequences and a gadolinium-enhanced T1-weighted spin-echo sequence. Low to intermediate signal intensity was usually seen in the largest part of the lesion on both spin-echo sequences, but smaller regions of hyperintensity on T1- and T2-weighted images and intermediate signal intensity throughout a lesion on T1-weighted images were also seen. All lesions enhanced but only two became iso- or hyperintense compared to fat. High clinical and pathological activity in three cases correlated with high signal intensity on both spin-echo sequences and with strong enhancement in two of the three. The presence of large veins or sinusoids on pathological examination did not correlate with the enhancement pattern.
authors.affiliation: Department of Radiology, St. Jan Hospital, Bruges, Belgium.
authors.forename: J W
authors.initials: JW
authors.lastname: Casselman
authors.forename: I
authors.initials: I
authors.lastname: De Jonge
authors.forename: L
authors.initials: L
authors.lastname: Neyt
authors.forename: C
authors.initials: C
authors.lastname: De Clercq
authors.forename: G
authors.initials: G
authors.lastname: D'Hont
mesh_terms: D000293:Adolescent; D000328:Adult; D003287:Contrast Media; D005147:Facial Bones / Q000473:pathology*; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis*; D005358:Fibrous Dysplasia, Monostotic / Q000175:diagnosis; D005359:Fibrous Dysplasia, Polyostotic / Q000175:diagnosis; D005682:Gadolinium; D006571:Heterocyclic Compounds; D006801:Humans; D007089:Image Enhancement; D007571:Jaw Diseases / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009916:Orbital Diseases / Q000175:diagnosis; D009942:Organometallic Compounds; D012886:Skull / Q000473:pathology*; D013100:Sphenoid Bone / Q000473:pathology; D013701:Temporal Bone / Q000473:pathology
chemical_list: D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C050823:gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate; D005682:Gadolinium