[Preventive chemotherapy for tuberculous infection. Arguments against].
Preventive chemotherapy with isoniazid (INH) is generally considered to be indicated in some patients with tuberculous infection who have a high risk of evolution towards disease. There are, however, some practical problems of treatment which may limit its application: correct assessment of tuberculin tests and risk factors, monitoring of treatment, patient compliance and management of possible side effects. Current treatment may not yet represent the ideal solution.
Zellweger
J P
JP
Dispensaire antituberculeux, Lausanne.
D003951:Diagnostic Errors; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects / Q000627:therapeutic use*; D008099:Liver / Q000187:drug effects; D010349:Patient Compliance; D014374:Tuberculin Test; D014376:Tuberculosis / Q000517:prevention & control*
D007538:Isoniazid