title: Treatment of T3a bladder cancer with iridium implantation.
abstract: A total of 7 patients with high grade, T3a (Stage B2) bladder cancer were treated with external radiation therapy and interstitial iridium implantation from May 1986 through March 1988. Follow-up has ranged from nineteen to sixty-one months with a median of forty months. One patient has required a cystectomy and is currently free of disease, and 1 patient has had recurrence of his cancer and metastatic carcinoma has developed; 5 are free of disease and have maintained their usual state of bladder function. Iridium implantation maintains bladder function and is effective therapy for selected individuals with localized, muscle-invading bladder cancer.
authors.affiliation: Department of Surgery, University of Michigan, Ann Arbor.
authors.forename: H B
authors.initials: HB
authors.lastname: Grossman
authors.forename: H M
authors.initials: HM
authors.lastname: Sandler
authors.forename: C
authors.initials: C
authors.lastname: Perez-Tamayo
mesh_terms: D000368:Aged; D001918:Brachytherapy; D002295:Carcinoma, Transitional Cell / Q000453:epidemiology / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000532:radiotherapy*
chemical_list: D007496:Iridium Radioisotopes