Preparation of autologous fibrin glue from pericardial blood.
To salvage patients' blood and improve hemostasis in cardiac operations, autologous fibrin glue was prepared in a new way by means of ethanol from pericardial blood. The yield from 44 mL of blood was 2.1 +/- 0.7 mL (mean +/- standard deviation) of fibrinogen concentrate with a concentration of 25.1 +/- 7.5 mg/mL; 2.7 mL of two-component glue was obtained after the addition of thrombin solution. The glue has the advantages of safety from transmission of viral diseases and from immunologic reactions.
Kjaergard
H K
HK
Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen, Denmark.
Weis-Fogh
U S
US
Thiis
J J
JJ
D000328:Adult; D000368:Aged; D001769:Blood; D001026:Coronary Artery Bypass; D005260:Female; D015718:Fibrin Tissue Adhesive; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010496:Pericardium
D015718:Fibrin Tissue Adhesive