A new pair of surface molecules involved in human IgE regulation.
The molecules controlling IgE production are the subject of intense study in the effort to find new ways to treat allergic diseases. One candidate, the CD23 molecule, a low affinity receptor for IgE, was recently identified to interact with another molecule, named CD21, in the regulation of IgE production.
Bonnefoy
J Y
JY
Glaxo Institute for Molecular Biology, Ouates/Geneva, Switzerland.
Pochon
S
S
Aubry
J P
JP
Graber
P
P
Gauchat
J F
JF
Jansen
K
K
Flores-Romo
L
L
D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000096:biosynthesis*; D015847:Interleukin-4 / Q000494:pharmacology; D017464:Receptors, Complement 3d / Q000378:metabolism; D017455:Receptors, IgE / Q000378:metabolism
D017464:Receptors, Complement 3d; D017455:Receptors, IgE; D015847:Interleukin-4; D007073:Immunoglobulin E