title: Immunonephelometry and radial immunodiffusion compared for measuring serum retinol-binding protein.
abstract: We compared a nephelometric method and a radial immunodiffusion (RID) assay for the measurement of retinol-binding protein in samples of serum from children with malignancies. The mean (+/- standard deviation) retinol-binding protein concentration as measured by the Behring Nephelometer was 31.0 +/- 15.6 mg/l; the mean by RID was 31.2 +/- 15.7 mg/l. This difference was not statistically significant by Student's t test (P = 0.6), and the correlation coefficient (r) was 0.87. Thus, the Behring Nephelometer method measures retinol-binding protein rapidly and as accurately as radial immunodiffusion.
authors.affiliation: INSERM U056, Hôpital de Bicêtre, France.
authors.forename: D J
authors.initials: DJ
authors.lastname: Malvy
authors.forename: J D
authors.initials: JD
authors.lastname: Povéda
authors.forename: M
authors.initials: M
authors.lastname: Debruyne
authors.forename: B
authors.initials: B
authors.lastname: Burtschy
authors.forename: L
authors.initials: L
authors.lastname: Dostalova
authors.forename: O
authors.initials: O
authors.lastname: Amédée-Manesme
mesh_terms: D016543:Central Nervous System Neoplasms / Q000097:blood; D002648:Child; D003627:Data Interpretation, Statistical; D006801:Humans; D005779:Immunodiffusion; D007938:Leukemia / Q000097:blood; D008223:Lymphoma / Q000097:blood / Q000503:physiopathology; D009369:Neoplasms / Q000097:blood*; D009391:Nephelometry and Turbidimetry; D012177:Retinol-Binding Proteins / Q000032:analysis*
chemical_list: D012177:Retinol-Binding Proteins