Two light-transducing membrane proteins: bacteriorhodopsin and the mammalian rhodopsin.
Site-directed mutagenesis has provided insight into the mechanisms of action of bacteriorhodopsin and rhodopsin. These studies are summarized here.
Khorana
H G
HG
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
D000595:Amino Acid Sequence; D000818:Animals; D001436:Bacteriorhodopsins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D002417:Cattle; D002462:Cell Membrane / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics; D006153:Guanosine Diphosphate / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D019617:Halobacterium salinarum / Q000235:genetics / Q000378:metabolism; D008027:Light; D008322:Mammals; D008954:Models, Biological; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D012243:Rhodopsin / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D013053:Spectrophotometry; D015293:Transducin / Q000378:metabolism
D011994:Recombinant Proteins; D006153:Guanosine Diphosphate; D001436:Bacteriorhodopsins; D006160:Guanosine Triphosphate; D012243:Rhodopsin; D015293:Transducin