title: [Successful delivery following continuous cytostatic therapy of a leukemic pregnant women].
abstract: The authors report about a successful labour and delivery after pregnancy with chronic myeloid leukemia treated with hydroxyurea. The haematological state of the mother could be well balanced with this cytostatic drug. The fetus was in a good condition during the whole pregnancy. At term a healthy newborn delivered with no signs of malformation or haematological disease. At a follow up visit 6 weeks after delivery the state of the mother and the newborn was satisfactory. The incidence of leukemia and pregnancy is rare. The creation of a central registry to pool experiences and data would help define optimum treatment regimens for this group of patients. A close cooperation among haematologist, obstetrician and pediatrician is emphasized.
authors.affiliation: Szent-Györgyi Albert Orvostudományi Egyetem Szülészeti és Nögyógyászati Klinika, Szeged.
authors.forename: F
authors.initials: F
authors.lastname: Szántó
authors.forename: L
authors.initials: L
authors.lastname: Kovács
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage / Q000627:therapeutic use*; D007231:Infant, Newborn; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy; D011256:Pregnancy Outcome
chemical_list: D000970:Antineoplastic Agents; D006918:Hydroxyurea