Increased depression in multiple sclerosis patients. A meta-analysis.
Clinical reports and experimental studies have conflicted on depression in multiple sclerosis (MS) patients. Recent reviews show that few controlled studies have been done. A comprehensive search of the literature revealed six studies that compared depression in MS patients with depression in comparison groups. The meta-analytic combination of these studies indicates that MS patients are significantly more depressed than comparison groups.
Schubert
D S
DS
Case Western Reserve University School of Medicine, Cleveland, OH.
Foliart
R H
RH
D000203:Activities of Daily Living / Q000523:psychology; D000328:Adult; D003866:Depressive Disorder / Q000523:psychology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000523:psychology* / Q000628:therapy; D019965:Neurocognitive Disorders / Q000523:psychology* / Q000628:therapy; D010555:Personality Inventory; D012307:Risk Factors; D012803:Sick Role