Cryopreservation of fetal stem cells.
Fetal liver cells may be transplanted, in utero, to treat disorders affecting the hematopoietic system. Conventional immunological methods were employed to determine whether pooled cryopreserved cells could be a suitable basis for a tissue bank. We found that cryopreservation did not adversely change the population, viability or immunological capacity of human fetal liver cells and therefore, pooled and cryopreserved fetal stem cells may be suitable for transplantation.
Ek
S
S
Department of Obstetrics and Gynecology, Karolinska Institute, Huddinge Hospital, Sweden.
Ringdén
O
O
Markling
L
L
Westgren
M
M
D015925:Cryopreservation; D016332:Fetal Tissue Transplantation / Q000379:methods*; D005333:Fetus / Q000166:cytology*; D006801:Humans; D008099:Liver / Q000166:cytology / Q000196:embryology*; D013234:Stem Cells / Q000166:cytology*