Oral candidiasis established in the sialoadenectomised rat.
Xerostomia provoked in rats by surgical removal of the major salivary glands favoured the development of oral candidiasis. After 32 weeks of inoculation, 20% of normal and 70% of xerostomic rats showed candidal infection on the tongue but only in xerostomic rats did candidiasis affect the pharyngeal aspect of the tongue.
Jorge
A O
AO
Department of Oral Pathology, Faculty of Dentistry, Piracicaba-SP, Brasil.
Totti
M A
MA
de Almeida
O P
OP
Scully
C
C
D000818:Animals; D002180:Candidiasis, Oral / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D004195:Disease Models, Animal; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012469:Salivary Glands / Q000502:physiology / Q000601:surgery; D014060:Tongue Diseases / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D014987:Xerostomia / Q000150:complications*