title: Ultrastructural similarity between bat and human mast cell secretory granules.
abstract: Mast cells in the tongue of the bat (Artibeus lituratus) show a well-developed Golgi area and abundant mitochondria in the granule-free perinuclear cytoplasm. Rough endoplasmic reticulum profiles, free ribosomes, mitochondria, bundles of filaments and a great number of secretory granules are found throughout the remaining cytoplasm. The granules, of various shapes and sizes, are simple containing an electron-dense, homogeneous matrix, coarse particles or cylindrical scrolls, or combinations (cylindrical scrolls with either electron-dense, homogeneous matrix or coarse particle contents). Up to now, scroll-containing granules have been considered to be a unique feature of human mast cells.
authors.affiliation: Department of Biology, IBILCE-UNESP, Säo José do Rio Prêto, Brazil.
authors.forename: S M
authors.initials: SM
authors.lastname: Oliani
authors.forename: I
authors.initials: I
authors.lastname: Vugman
authors.forename: M C
authors.initials: MC
authors.lastname: Jamur
mesh_terms: D000818:Animals; D002685:Chiroptera / Q000033:anatomy & histology*; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000648:ultrastructure*; D014059:Tongue / Q000166:cytology