title: Bacterial interspersed mosaic elements (BIMEs) are present in the genome of Klebsiella.
abstract: Bacterial interspersed mosaic elements (BIMEs) constitute a family of highly repetitive sequences containing palindromic units (PUs), also called repetitive extragenic palindromes (REPs). BIMEs were originally described in Escherichia coli and Salmonella typhimurium. We show here, by determining the nucleotide sequence of two intergenic regions of Klebsiella pneumoniae, by computer searches, and by hybridization, that sequences with similar characteristics are found in the genome of several Klebsiella species. This reinforces the idea that BIMEs play general and important roles in enterobacteria such as in the organization of the bacterial chromosome.
authors.affiliation: Unité de Programmation Moléculaire et Toxicologie Génétique, CNRS URA 1444, Institut Pasteur, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Bachellier
authors.forename: D
authors.initials: D
authors.lastname: Perrin
authors.forename: M
authors.initials: M
authors.lastname: Hofnung
authors.forename: E
authors.initials: E
authors.lastname: Gilson
mesh_terms: D001483:Base Sequence; D015342:DNA Probes; D004269:DNA, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics; D014644:Genetic Variation; D016680:Genome, Bacterial; D007709:Klebsiella / Q000235:genetics*; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D012486:Salmonella typhimurium / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
chemical_list: D015342:DNA Probes; D004269:DNA, Bacterial