title: Evaluation of transient heart murmur resembling pulmonary artery stenosis in term infants by Doppler and M-mode echocardiography.
abstract: Four term infants with transient murmurs resembling that of pulmonary artery stenosis were examined. A grade 3/6 systolic ejection murmur was transmitted clearly to the entire precordium and the back. This murmur was first detected 7 days after birth in 1 infant and at a 1-month medical check in the other 3. The murmur continued for 7 to 22 weeks, with an average of 12 weeks. It gradually localized in the region of the left sternal border, and eventually disappeared. At the first medical examination, peak velocities of over 2.0 m/s, in the left or right pulmonary artery, were detected by a pulsed Doppler. The diameter of the right pulmonary artery was small (mean, 58 +/- 8%; range, 46 to 64% of predicted normal). When the heart murmur disappeared, the diameter of the right pulmonary artery (mean, 97 +/- 28%; range, 70 to 126%) had increased significantly (p < 0.05). Peak velocities in the right pulmonary arteries had decreased significantly (2.22 +/- 0.37 m/s vs 1.13 +/- 0.10 m/s, p < 0.01). We suggest that hypoplasia of pulmonary artery branches, in relation to the main trunk, is the main cause of the murmur resembling pulmonary artery stenosis.
authors.affiliation: Department of Cardiovascular Surgery, Kinki University School of Medicine, Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyake
authors.forename: T
authors.initials: T
authors.lastname: Yokoyama
mesh_terms: D001157:Arterial Occlusive Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D006337:Heart Murmurs / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011651:Pulmonary Artery / Q000033:anatomy & histology / Q000254:growth & development*