title: [The transformation of a cervical chordoma into an anaplastic tumor. A case report and review of the literature].
abstract: The authors describe a case of a cervical chordoma in a 28-year-old man with local recurrence and metastasis. Particular attention is paid to the fact that complete malignant transformation was observed during the follow-up. A review of the literature is undertaken chronicling the documented associations of chordoma and malignant neoplasm. Followed by a discussion of the three causes proposed to explain this phenomenon. Further on the current opinion on the therapy methods of chordomas is reviewed.
authors.affiliation: Radiologische Klinik, Universität Heidelberg.
authors.forename: A P
authors.initials: AP
authors.lastname: Wichmann
authors.forename: D M
authors.initials: DM
authors.lastname: Latz
mesh_terms: D000328:Adult; D000708:Anaplasia / Q000473:pathology; D002277:Carcinoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D002817:Chordoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007796:Laminectomy; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D012086:Reoperation