Urinary endothelin-1: not a useful marker for preeclampsia.
Urinary endothelin-1 levels were assayed from 50 gravidas with preeclampsia and 11 with normotension in the third trimester of pregnancy. Urinary endothelin-1 levels (mean +/- SEM) were similar between gravidas with normotension and preeclampsia (62.7 +/- 7.5 vs 79.8 +/- 9.3 fmol/mg urinary creatinine, respectively). Urinary endothelin-1 excretion is not significantly increased in patients with preeclampsia and therefore not a good marker for preeclampsia.
Barton
J R
JR
Department of Obstetrics and Gynecology, University of Tennessee, Memphis.
Sibai
B M
BM
Whybrew
W D
WD
Mercer
B M
BM
D016232:Endothelins / Q000652:urine*; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000652:urine*; D011247:Pregnancy / Q000652:urine; D011263:Pregnancy Trimester, Third; D012016:Reference Values; D012044:Regression Analysis
D016232:Endothelins