title: Human interleukin-2-IgM heavy-chain-fusion proteins are cytotoxic for cells expressing the IL2 receptor.
authors.affiliation: Institut National pour la Santé et la Recherche Médicale (INSERM U.211), Nantes, France.
authors.forename: H
authors.initials: H
authors.lastname: Vie
authors.forename: T
authors.initials: T
authors.lastname: Gauthier
authors.forename: R
authors.initials: R
authors.lastname: Breathnach
authors.forename: M
authors.initials: M
authors.lastname: Bonneville
authors.forename: A
authors.initials: A
authors.lastname: Godard
authors.forename: J
authors.initials: J
authors.lastname: Dietrich
authors.forename: G
authors.initials: G
authors.lastname: Karam
authors.forename: M C
authors.initials: MC
authors.lastname: Gesnel
authors.forename: M A
authors.initials: MA
authors.lastname: Peyrat
authors.forename: Y
authors.initials: Y
authors.lastname: Jacques
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D007075:Immunoglobulin M / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D007376:Interleukin-2 / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology*; D015375:Receptors, Interleukin-2 / Q000187:drug effects / Q000378:metabolism*; D011993:Recombinant Fusion Proteins / Q000378:metabolism / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014162:Transfection; D014407:Tumor Cells, Cultured
chemical_list: D007143:Immunoglobulin Heavy Chains; D007075:Immunoglobulin M; D007376:Interleukin-2; D015375:Receptors, Interleukin-2; D011993:Recombinant Fusion Proteins