Growth factors: regulation of normal and neoplastic growth.
This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.
Pusztai
L
L
University of Oxford, Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, U.K.
Lewis
C E
CE
Lorenzen
J
J
McGee
J O
JO
D002455:Cell Division / Q000502:physiology; D006131:Growth Inhibitors / Q000378:metabolism; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000378:metabolism*
D006131:Growth Inhibitors; D006133:Growth Substances