title: Management of unusual presentations of acute leukemia.
abstract: Unusual patterns of presentation of acute leukemia are discussed, with an emphasis on the diagnostic and therapeutic challenges that they pose. Clinical syndromes reviewed include the leukostasis syndrome, disseminated intravascular coagulation, granulocytic sarcoma, central nervous system leukemia, leukemia cutis, Sweet's syndrome, pyoderma gangrenosum, and acute leukemia diagnosed during pregnancy. Each of these uncommon presentations of acute leukemia has a unique impact on patient management.
authors.affiliation: Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York.
authors.forename: M R
authors.initials: MR
authors.lastname: Baer
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000453:epidemiology; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000628:therapy; D005260:Female; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007938:Leukemia / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D007951:Leukemia, Myeloid / Q000628:therapy; D017254:Leukemic Infiltration; D007964:Leukocytosis / Q000209:etiology / Q000401:mortality; D008297:Male; D008578:Meninges / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy; D017511:Pyoderma Gangrenosum / Q000209:etiology / Q000628:therapy; D012867:Skin / Q000473:pathology; D016463:Sweet Syndrome / Q000209:etiology / Q000628:therapy; D013577:Syndrome
chemical_list: D000970:Antineoplastic Agents