title: Consistent numerical chromosome aberrations in congenital fibrosarcoma.
abstract: Cytogenetic analysis of a congenital fibrosarcoma of the volar forearm from a 2.5-month-old boy revealed a mosaic karyotype 46,XY/49,XY,+11,+17,+20. This pattern of specific trisomies provides additional support to the cytogenetic findings in five cases of congenital fibrosarcoma reported previously. Trisomy 11 appears to be characteristic of congenital fibrosarcoma with additional trisomies 8, 17, and 20 as common findings.
authors.affiliation: Department of Human Genetics, University of Pittsburgh, Pennsylvania.
authors.forename: S
authors.initials: S
authors.lastname: Sankary
authors.forename: P S
authors.initials: PS
authors.lastname: Dickman
authors.forename: E
authors.initials: E
authors.lastname: Wiener
authors.forename: W
authors.initials: W
authors.lastname: Robichaux
authors.forename: W P
authors.initials: WP
authors.lastname: Swaney
authors.forename: P S
authors.initials: PS
authors.lastname: Malone
authors.forename: S M
authors.initials: SM
authors.lastname: Gollin
mesh_terms: D002869:Chromosome Aberrations / Q000235:genetics*; D005354:Fibrosarcoma / Q000151:congenital* / Q000235:genetics* / Q000473:pathology; D005542:Forearm; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D014407:Tumor Cells, Cultured / Q000473:pathology