title: Diabetic nephropathy: a comprehensive approach.
abstract: By the time the traditional dipstick test shows excess urinary albumin, glomerular damage may be beyond repair and nephrotic syndrome virtually guaranteed. More sensitive assays provide earlier warning, allowing the clinician to institute a surveillance and antihypertensive program that--along with dietary glycemic control--can stave off disease progression.
authors.affiliation: Yale University School of Medicine, New Haven.
authors.forename: R L
authors.initials: RL
authors.lastname: Mahnensmith
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002985:Clinical Protocols / Q000592:standards; D002986:Clinical Trials as Topic; D003376:Counseling / Q000592:standards; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006830:Hydralazine / Q000494:pharmacology / Q000627:therapeutic use; D006852:Hydrochlorothiazide / Q000494:pharmacology / Q000627:therapeutic use; D007328:Insulin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D010347:Patient Care Planning / Q000592:standards; D051381:Rats; D012110:Reserpine / Q000494:pharmacology / Q000627:therapeutic use; D012307:Risk Factors; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D007328:Insulin; D006852:Hydrochlorothiazide; D006830:Hydralazine; D012110:Reserpine