title: Malignant melanoma of the nasal cavity and paranasal sinuses.
abstract: Malignant melanoma affecting the nasal cavity and paranasal sinuses is a rare condition with a poor prognosis. The Head and Neck Oncology Clinic at the University Hospital Nottingham has treated 16 patients in an 8-year-period. Twelve patients were treated with primary radical surgery and salvage radiotherapy was used for 7 patients with local recurrence. This resulted in tumour shrinkage in 4 patients. Eight patients treated surgically, have died of systemic spread. Four are currently alive, although 2 have local disease.
authors.affiliation: Combined Head and Neck Oncology Clinic, University Hospital, Queen's Medical Centre, Nottingham, UK.
authors.forename: A C
authors.initials: AC
authors.lastname: Thompson
authors.forename: D A
authors.initials: DA
authors.lastname: Morgan
authors.forename: P J
authors.initials: PJ
authors.lastname: Bradley
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D015996:Survival Rate