title: Temperature changes associated with forebrain ischemia in the gerbil.
abstract: Changes in brain temperature during and following ischemia have not been systematically examined in the gerbil. In this study, gerbils were subjected to a 5-min bilateral carotid artery occlusion. During surgery, skull and body temperatures were maintained with a heated water blanket and a homeothermic blanket unit, respectively. Rectal, skull and brain temperatures were monitored throughout ischemia and for up to 3 h in the post-ischemic period. Intra-ischemic brain temperature fell by approximately 1.5 degrees C even though skull and rectal temperatures remained at normal values. Since brain temperature modulates the extent of ischemic injury it may not be sufficient to rely on skull and/or rectal temperature readings, especially during periods of anesthesia.
authors.affiliation: Division of Basic Medical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Canada.
authors.forename: F
authors.initials: F
authors.lastname: Colbourne
authors.forename: S M
authors.initials: SM
authors.lastname: Nurse
authors.forename: D
authors.initials: D
authors.lastname: Corbett
mesh_terms: D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D001921:Brain / Q000473:pathology / Q000502:physiology; D017536:Carotid Artery, Common / Q000502:physiology; D005260:Female; D005849:Gerbillinae; D002546:Ischemic Attack, Transient / Q000473:pathology / Q000503:physiopathology*