[Differential determination of fibrinogen degradation products in assessment of the stages of plasma consumption in patients with infection and liver cirrhosis].
In the present study soluble fibrin complexes and fibrin(ogen) degradation products are determined in patients with sepsis and liver-cirrhotic simultaneously by means of FM-Test, FDP-Kit and SCT in order to detect the different and early phases of disseminated intravascular coagulation. According to the possible configuration of test results 43 patients (sepsis n = 23, liver cirrhotic n = 20) could be grouped in 4 phases. The FDP-concentrations and the FM-Test-result appear to be independent from one another. A positive FM-Test was found at least once in 35% of patients with liver-cirrhotic and 26% of patients with sepsis. The correlation coefficient for the two FDP-Tests (FDP-Kit and SCT) was r = 0.97 (p < 0.001) for liver-cirrhotic and r = 0.98 (p < 0.001) for sepsis.
Raschka
C
C
Medizinische Klinik II, Justus-Liebig-Universität Giessen.
Róka
L
L
D004211:Disseminated Intravascular Coagulation / Q000097:blood* / Q000145:classification / Q000175:diagnosis; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood* / Q000175:diagnosis; D011933:Reagent Kits, Diagnostic; D012016:Reference Values; D012772:Shock, Septic / Q000097:blood* / Q000175:diagnosis
D005338:Fibrin Fibrinogen Degradation Products; D011933:Reagent Kits, Diagnostic