A triangular conditioning voltage wave does not influence spontaneous neuronal activity in the rat striatum.
A triangular potential wave applied shortly before each measuring triple pulse has been used in in vivo voltammetric experiments to ensure the maintenance of a high level of stability and sensitivity in the carbon fiber electrode. To investigate whether a triangular wave (0- +/- 1500 mV, 10 V/s slope) and a consecutive triple pulse affect spontaneous neuronal firing, extracellular recordings were made in the rat striatum at a distance of about 200-300 microns from the carbon fiber electrode while these potentials were being delivered. No significant change in the rate of spontaneous firing was found. A triangular pulse has proven to be very effective in lengthening the measurement lifetime of the carbon fiber electrode without interfering with the spontaneous activity of striatal neurons.
Nakazato
T
T
Department of Physiology, Juntendo University School of Medicine, Tokyo, Japan.
Hosoda
S
S
Akiyama
A
A
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D003342:Corpus Striatum / Q000166:cytology / Q000502:physiology*; D004298:Dopamine / Q000494:pharmacology; D004558:Electric Stimulation; D004566:Electrodes; D005110:Extracellular Space / Q000502:physiology; D008297:Male; D009474:Neurons / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar
D001205:Ascorbic Acid; D004298:Dopamine