Reconstruction of the growing cricoid with a composite graft of demineralized bovine bone and autogenous perichondrium; a comparative study in rabbits.
In growing rabbits, the feasibility of a new type of composite graft for the reconstruction of defects in the cricoid ring is studied. This graft consists of Demineralized Bovine Bone matrix (DBBM) enfolded in a perichondrial flap. The cartilage formed in the DBBM by cells, derived from the perichondrium, is demonstrated to provide a valuable substitute for resected parts of the cricoid. A specific feature of this reconstruction is that it allows further growth and does not result in a secondary stenosis during later development.
Bean
J K
JK
Department of Otorhinolaryngology, Sophia Children's Hospital, Erasmus University, Rotterdam, The Netherlands.
Verwoerd-Verhoef
H L
HL
Meeuwis
J
J
Verwoerd
C D
CD
D000818:Animals; D001857:Bone Matrix / Q000637:transplantation*; D016025:Bone Transplantation; D002356:Cartilage / Q000637:transplantation*; D002417:Cattle; D003413:Cricoid Cartilage / Q000254:growth & development / Q000601:surgery*; D005260:Female; D011817:Rabbits; D013524:Surgical Flaps