title: Osteogenesis imperfecta and hyperplastic callus formation: light- and electron-microscopic findings.
abstract: In rare cases of osteogenesis imperfecta, an "overshoot" growth of new bone may occur, which, clinically gives the impression of a tumour. This condition is known as hyperplastic callus formation. Morphology showed an excessive mixed desmal-chondral osteoneogenesis. Atypical collagen fibrils in non-callus tissue represent an indicator for this callus formation in individual patients.
authors.affiliation: Department of Pathology, University of Erlangen, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Stöss
authors.forename: B
authors.initials: B
authors.lastname: Pontz
authors.forename: U
authors.initials: U
authors.lastname: Vetter
authors.forename: A
authors.initials: A
authors.lastname: Karbowski
authors.forename: R
authors.initials: R
authors.lastname: Brenner
authors.forename: J
authors.initials: J
authors.lastname: Spranger
mesh_terms: D002146:Bony Callus / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D008854:Microscopy, Electron; D010013:Osteogenesis Imperfecta / Q000150:complications / Q000473:pathology*