title: [A case of breast cancer with multiple organ metastases in which single low dose administration of 5'-DFUR proved effective].
abstract: A 58-year-old woman with multiple organ metastases from breast cancer who had undergone radical mastectomy three years ago, was treated with oral 5'-DFUR 600 mg/day. Complete remission (CR) of lymph node metastasis has been maintained for twenty-two weeks, with partial response (PR) against skin, liver and pleural metastases from 94 weeks of treatment. The patient, who continues to be treated, is well and enjoying a favorable quality of life. 5'-DFUR is considered to be an effective first choice for treating a patient with advanced or recurrent breast cancer.
authors.affiliation: 2nd Dept. of Surgery, Hiroshima University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kataoka
authors.forename: T
authors.initials: T
authors.lastname: Okamoto
authors.forename: T
authors.initials: T
authors.lastname: Gotoh
authors.forename: S
authors.initials: S
authors.lastname: Sadamoto
authors.forename: M
authors.initials: M
authors.lastname: Nishiki
authors.forename: K
authors.initials: K
authors.lastname: Dohi
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D004334:Drug Administration Schedule; D005260:Female; D005467:Floxuridine / Q000008:administration & dosage*; D006801:Humans; D008207:Lymphatic Metastasis; D015409:Mastectomy, Radical; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011379:Prognosis; D011788:Quality of Life; D013629:Tamoxifen / Q000008:administration & dosage
chemical_list: D000970:Antineoplastic Agents; D005467:Floxuridine; D013629:Tamoxifen; D017258:Medroxyprogesterone Acetate; C025034:doxifluridine