title: [Risk factors of perioperative morbidity and mortality in colorectal cancer with special reference to tumor stage, site and age].
abstract: The perioperative risk was prospectively analyzed in 511 patients with colorectal cancer, out of which 5% had an emergency procedure. The morbidity rate was 23.6% without an association with tumour stage or localization. The incidence of nonsurgical complications rose with increasing age because of a rising number of concomitant illnesses (< 50: 5.7%, > 80: 28.1%). The morbidity was associated with an increasing blood loss during the operation (< 500 ml: 10.6%, > 2000 ml: 30.4%), but not with the type of treatment. The overall operative mortality rate was 2.3% with the same rate of surgical complications and complications of preexisting conditions. Morbidity and mortality following emergency procedure were 56%, respectively 20%, expressing mainly septical complications of colorectal cancer.
authors.affiliation: Klinik für Allgemein und Abdominalchirurgie, Johannes Gutenberg Universität Mainz.
authors.forename: H
authors.initials: H
authors.lastname: Menke
authors.forename: J M
authors.initials: JM
authors.lastname: Graf
authors.forename: A
authors.initials: A
authors.lastname: Heintz
authors.forename: A
authors.initials: A
authors.lastname: Klein
authors.forename: T
authors.initials: T
authors.lastname: Junginger
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D004630:Emergencies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000401:mortality*; D012307:Risk Factors