Ultrastructural study of Cryptosporidium development in Madin-Darby canine kidney cells.
Transmission electron microscope studies have been made into phases of the life cycle of a bovine isolate of Cryptosporidium cultured in vitro on Madin-Darby canine kidney cells. The cytoplasm of parasitized cells was noticeably altered, including marked vacuolization and the appearance of membrane structures close to the developing parasites. These changes suggest that the protozoan may release cytopathogenic factors.
Rosales
M J
MJ
Department of Molecular Parasitology, Faculty of Sciences, University of Granada, Spain.
Mascaro
C
C
Osuna
A
A
D000818:Animals; D002460:Cell Line; D016785:Cryptosporidium parvum / Q000254:growth & development* / Q000648:ultrastructure; D004285:Dogs; D007668:Kidney; D008854:Microscopy, Electron