Comparison of scintigraphy with indium-111 leukocyte scan and ultrasonography in assessment of X-ray-demonstrated lesions of Crohn's disease.
The aim of this study was to compare the results obtained with an indium-111 scan with those obtained with less expensive and harmless ultrasonography to evaluate the location and inflammatory activity of Crohn's disease. Thirty-one patients previously studied with x-ray underwent abdominal 111In scans and ultrasonography (US). Sensitivity and specificity of US in detecting lesions seen with 111In scan were 77% and 92.8%, respectively. Sensitivity and specificity of 111In scan in detecting x-ray-defined lesions were 69.2% and 92.7%; the figures for US were 73% and 93.3%, respectively. Considering the evaluation of disease activity, ultrasonographic bowel wall thickness was significantly related to scintigraphic intensity of emission (r = 0.75 P < 0.01). Our experience suggests that US provided information about the location and inflammatory activity of lesions similar to that obtained from 111In scan.
Brignola
C
C
Istituto di Clinica Medica e Gastroenterologia, Università di Bologna, Italy.
Belloli
C
C
Iannone
P
P
De Simone
G
G
Corbelli
C
C
Levorato
M
M
Arienti
V
V
Boriani
L
L
Gionchetti
P
P
Belluzzi
A
A
D000005:Abdomen / Q000000981:diagnostic imaging; D003424:Crohn Disease / Q000175:diagnosis* / Q000453:epidemiology; D003952:Diagnostic Imaging; D006801:Humans; D007205:Indium Radioisotopes; D007962:Leukocytes; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014463:Ultrasonography
D007205:Indium Radioisotopes