title: Epidermodysplasia verruciformis and malignant thymoma.
abstract: We describe a patient with a long history of skin lesions clinically and histologically consistent with epidermodysplasia verruciformis (EV) who developed malignant thymoma. HPV-9DNA was found in the macular lesion and HPV-4DNA and HPV-9DNA in the coexistent common warts. Thrombocytopenia and hypogammaglobulinaemia preceded the diagnosis of thymoma. Our patient seems to represent an example of an EV-like syndrome in immunodeficiency.
authors.affiliation: Department of Dermatology, University of Pretoria, Republic of South Africa.
authors.forename: W K
authors.initials: WK
authors.lastname: Jacyk
authors.forename: J A
authors.initials: JA
authors.lastname: Hazelhurst
authors.forename: L
authors.initials: L
authors.lastname: Dreyer
authors.forename: M A
authors.initials: MA
authors.lastname: Coccia-Portugal
mesh_terms: D000328:Adult; D004819:Epidermodysplasia Verruciformis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology; D013945:Thymoma / Q000150:complications* / Q000473:pathology