title: Compensatory function of central dopaminergic system for suppressing psychic seizures--repeated plasma homovanillic acid measurement in refractory temporal lobe epilepsy.
abstract: Repeatedly measured plasma homovanillic acid concentration, as a clinically available index of central dopaminergic activity in a patient with temporal lobe epilepsy during a drug-free period, was significantly correlated with seizure frequency in the week immediately following, but not preceding, blood sampling days. This result suggests a compensatory function of the dopaminergic system in suppressing refractory psychic seizures.
authors.affiliation: Department of Neuropsychiatry, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fukuda
authors.forename: S I
authors.initials: SI
authors.lastname: Niwa
authors.forename: N
authors.initials: N
authors.lastname: Kumagai
authors.forename: S
authors.initials: S
authors.lastname: Nagakubo
authors.forename: Y
authors.initials: Y
authors.lastname: Shirayama
authors.forename: O
authors.initials: O
authors.lastname: Hashimoto
authors.forename: A
authors.initials: A
authors.lastname: Hata
authors.forename: T
authors.initials: T
authors.lastname: Kameyama
authors.forename: N
authors.initials: N
authors.lastname: Anzai
mesh_terms: D000328:Adult; D002851:Chromatography, High Pressure Liquid; D004833:Epilepsy, Temporal Lobe / Q000097:blood* / Q000503:physiopathology; D005260:Female; D006212:Hallucinations / Q000503:physiopathology; D006719:Homovanillic Acid / Q000097:blood*; D006801:Humans; D011954:Receptors, Dopamine / Q000502:physiology*
chemical_list: D011954:Receptors, Dopamine; D006719:Homovanillic Acid