title: Clostridium perfringens septicemia with massive hemolysis.
abstract: Massive hemolysis and renal failure are rare complications of infection with Clostridium perfringens, resulting in a very high mortality rate (70-100%). The severity of the infection depends on the presence of underlying conditions such as malignancies and diabetes mellitus. In patients without underlying disorders, massive hemolysis and anuria have been observed in only eight cases, according to recent reports. This case report describes a 61-year-old man who died of C. perfringens septicemia with massive hemolysis and anuria less than 4 h after admittance to the hospital, despite rapid and adequate antibiotic treatment. No focal infection was found.
authors.affiliation: Medical Dept., Buskerud Central Hospital, Drammen, Norway.
authors.forename: B
authors.initials: B
authors.lastname: Rogstad
authors.forename: S
authors.initials: S
authors.lastname: Ritland
authors.forename: S
authors.initials: S
authors.lastname: Lunde
authors.forename: A G
authors.initials: AG
authors.lastname: Hagen
mesh_terms: D001002:Anuria / Q000209:etiology; D016470:Bacteremia / Q000150:complications / Q000382:microbiology*; D003015:Clostridium Infections / Q000150:complications / Q000382:microbiology*; D003016:Clostridium perfringens; D006461:Hemolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology