title: [Changes and progress in the treatment of TTP--protocols of therapeutic plasma infusion and plasma exchange--therapeutic results by the Japanese and Canadian Study Groups].
abstract: Plasma exchange (PE) and plasma infusion (PI) are effective in the treatment of TTP (thrombotic thrombocytopenic purpura). Comparison of PE and PI in the treatment of TTP was carried out by the Canadian Apheresis Study Group, which reported that PE was superior to PI. The Japanese TTP Study Group made a therapeutic protocol in which a smaller volume of Fresh frozen plasma (FFP) was used in the treatment with PI. The efficacy of PE and PI was similar. The results suggest that the volume of FFP necessary for effective treatment is not very large.
authors.affiliation: Department of Transfusion Medicine, Kyoto University Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Ito
authors.forename: A
authors.initials: A
authors.lastname: Hattori
authors.forename: S
authors.initials: S
authors.lastname: Hirosawa
authors.forename: J
authors.initials: J
authors.lastname: Takamatsu
authors.forename: E
authors.initials: E
authors.lastname: Kakishita
authors.forename: K
authors.initials: K
authors.lastname: Fujimura
mesh_terms: D016913:Blood Component Transfusion; D002170:Canada; D003937:Diagnosis, Differential; D006801:Humans; D007564:Japan; D010951:Plasma Exchange; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy*
chemical_list: D010975:Platelet Aggregation Inhibitors