The determination of a new inhalational anaesthetic, sevoflurane, using an internal standard, xenon, by gas chromatography/mass spectrometry/selected ion monitoring.
A novel determination method for a new inhalation anaesthetic, sevoflurane, in a closed circuit in the presence of carbon dioxide absorbents is investigated using gas chromatography/selected ion monitoring with xenon as an internal standard. The decrease rate of sevoflurane with soda lime was 0.22% +/- 0.158/h (mean +/- SD), while that with baralyme was 0.57% +/- 0.115/h (mean +/- SD).
Miyano
K
K
Department of Anesthesiology, Jikei University School of Medicine, Tokyo, Japan.
Tanifuji
Y
Y
Obata
T
T
D000769:Anesthesia, Inhalation; D000777:Anesthetics / Q000032:analysis*; D004987:Ethers / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D007477:Ions; D008738:Methyl Ethers; D012015:Reference Standards; D000077149:Sevoflurane; D014978:Xenon / Q000737:chemistry*
D000777:Anesthetics; D004987:Ethers; D007477:Ions; D008738:Methyl Ethers; D000077149:Sevoflurane; D014978:Xenon