Safety studies of modified hemoglobin as an oxygen-carrying blood substitute.
Chang
T M
TM
Artificial Cells and Organs Research Centre, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
D000818:Animals; D001772:Blood Cell Count / Q000187:drug effects; D001777:Blood Coagulation / Q000187:drug effects; D001802:Blood Substitutes / Q000494:pharmacology / Q000633:toxicity; D003167:Complement Activation / Q000187:drug effects; D004339:Drug Compounding; D004353:Drug Evaluation, Preclinical; D006454:Hemoglobins / Q000276:immunology / Q000494:pharmacology / Q000633:toxicity; D006801:Humans; D015539:Platelet Activation / Q000187:drug effects; D011732:Pyridoxal Phosphate / Q000031:analogs & derivatives* / Q000276:immunology / Q000494:pharmacology / Q000633:toxicity; D051381:Rats; D012449:Safety
D001802:Blood Substitutes; D006454:Hemoglobins; C030939:polyhemoglobin-pyridoxal-5-phosphate; D011732:Pyridoxal Phosphate