Chromosome cultures from human cartilage.
Choosing the best post-mortem biological tissue source for chromosomal studies is a challenge for cytogeneticists. Acceptable cytogenetic results are difficult to obtain from macerated and necrosed tissues. This report describes a method that is carried out after enzymatic digestion of cartilage from human fetuses and infants. It is currently employed successfully in our laboratory and our experience has shown that human cartilage could well be the tissue of choice for cytogenetic studies in stillborn fetuses and dead infants.
Urioste
M
M
ECEMC, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
D002356:Cartilage / Q000648:ultrastructure*; D002469:Cell Separation; D002478:Cells, Cultured; D002877:Chromosomes, Human / Q000648:ultrastructure*; D003584:Cytological Techniques; D005069:Evaluation Studies as Topic; D005313:Fetal Death / Q000235:genetics; D005821:Genetic Techniques; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping