title: Rapid development of a tophus following ipsilateral hemiparesis.
abstract: An 85 year old man with a longstanding history of non-tophaceous gout developed a single large tophus, unassociated with inflammation, on his paretic leg over a six week period following an acute hemiplegia. The rapidity of tophus formation, its localisation to the paretic limb, and the apparent blunting of the acute inflammatory response represent a previously unreported interaction between gout and neurological deficit.
authors: Department of Health Care of the Elderly, City Hospital, Nottingham, United Kingdom.
authors: C F
authors: CF
authors: Donegan
authors: P
authors: P
authors: Berman
authors: M
authors: M
authors: Doherty
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D002561:Cerebrovascular Disorders / Q000150:complications*; D005534:Foot Diseases / Q000209:etiology; D006073:Gout / Q000209:etiology* / Q000378:metabolism; D006429:Hemiplegia / Q000150:complications*; D006801:Humans; D008297:Male; D013997:Time Factors; D014527:Uric Acid / Q000032:analysis*
chemical_list: D014527:Uric Acid