[Activated partial thromboplastin time. Evaluation of sensitivity and validity for determination of factor VIII coagulant activity].
The authors evaluate the sensibility and validity of some reagents for activated partial thromboplastin time during construction of a curve for measurement of factor VIII coagulant activity. For every reagent three clotting factor VIII deficient plasmas have been used; Baldacci, Dade and Behering. Significant differences in results between every reagent for aPTT and laboratory have been observed. By these results the Authors show the best reagent for aPTT. Future fields of research have been analyzed.
Camici
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Insegnamento di Metodologia Clinica, Università degli Studi di Pisa.
Evangelisti
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D000293:Adolescent; D000328:Adult; D005169:Factor VIII / Q000502:physiology*; D005260:Female; D006801:Humans; D007202:Indicators and Reagents; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D012016:Reference Values; D012680:Sensitivity and Specificity
D007202:Indicators and Reagents; D005169:Factor VIII
Tempo parziale di tromboplastina attivata. Valutazione della sensibilità e validità per la determinazione del fattore VIII attività coagulante.