Prominent telangiectasia associated with marked bleeding in CREST syndrome.
A 64-year-old woman with CREST syndrome developed prominent telangiectases mimicking hereditary hemorrhagic telangiectasia (HHT) of Osler-Rendu-Weber. We have been following her since she first came to us with discrete telangiectatic mats and Raynaud's phenomenon 11 years ago. Telangiectatic lesions have been seen on her larynx and esophagus in addition to commonly affected sites. She has experienced spontaneous epistaxis and marked bleeding from the lesions on her lips, oral mucous membrane, and soles. This case illuminates new aspects of telangiectasia in CREST syndrome.
Ueda
M
M
Department of Dermatology, Okayama University Medical School, Japan.
Abe
Y
Y
Fujiwara
H
H
Fujimoto
W
W
Arakawa
K
K
Arata
J
J
Yoshioka
T
T
Tomoda
J
J
Katayama
H
H
D002114:Calcinosis / Q000473:pathology; D003937:Diagnosis, Differential; D004935:Esophageal Diseases / Q000473:pathology; D005260:Female; D006470:Hemorrhage / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D011928:Raynaud Disease / Q000473:pathology; D012595:Scleroderma, Systemic / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000473:pathology*; D013577:Syndrome; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000175:diagnosis; D013684:Telangiectasis / Q000473:pathology*