The role of host tyrosine phosphorylation in bacterial pathogenesis.
Recent studies on the pathogenic mechanisms of several bacterial genera, including the Yersinia, Salmonella and Escherichia, have revealed novel strategies of infection that involve the signal transduction processes of eukaryotic cells. These model systems are reviewed here, with emphasis on the role of tyrosine phosphorylation in these bacterial-host cell interactions.
Bliska
J B
JB
Department of Microbiology, State University of New York, Stony Brook School of Medicine 11794.
Falkow
S
S
D000818:Animals; D004926:Escherichia coli / Q000472:pathogenicity*; D006801:Humans; D010766:Phosphorylation; D012475:Salmonella / Q000472:pathogenicity*; D014443:Tyrosine / Q000378:metabolism*; D015007:Yersinia / Q000472:pathogenicity*
D014443:Tyrosine