Paradoxical cerebral embolism originating from thrombus in tumour veins as presenting manifestation of retroperitoneal liposarcoma.
The coincidence of pulmonary and systemic emboli suggests paradoxical embolism. We present the case of a young man in whom a blood clot travelled from the veins in a retroperitoneal liposarcoma via a patent foramen ovalis to the systemic arterial circulation. Young patients with embolic disease but no obvious source of thrombus may have underlying neoplastic disease. Venous thrombosis is a frequent complication of neoplastic disease. Arterial embolism associated with neoplasm is, however, not widely recognised.
Garrett
P J
PJ
Department of Medicine and Pathology, Princess Margaret Hospital, Swindon.
Mulcahy
K
K
Burden
R J
RJ
Ng
W C
WC
Price
P A
PA
D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology*; D008080:Liposarcoma / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000209:etiology; D012186:Retroperitoneal Neoplasms / Q000098:blood supply*; D013927:Thrombosis / Q000150:complications*