title: Evaluation of erectile dysfunction by dynamic infusion cavernosometry and cavernosography (DICC). Multi-institutional study.
abstract: In a cooperative, private practice, multi-institutional impotence study, dynamic infusion cavernosometry and cavernosography (DICC) was performed on 743 patients to make an accurate diagnosis and/or identify candidates for penile revascularization. Maximum equilibrium intracorporeal pressure achieved following papaverine and phentolamine injection (Phase I) averaged 29.42 +/- 0.76 mm Hg, approximately one third of normal erection pressure. Corporeal pressure fall from 150 mm Hg over thirty seconds (cavernosometry) averaged 82.38 +/- 1.33 mm Hg (Phase II). The gradient between systolic and cavernosal artery pressure averaged 42.84 +/- 1.12 mm Hg on the right and 43.33 +/- 1.13 mm Hg on the left (Phase III). Cavernosography at 90 mm Hg erection pressure was performed in Phase IV. Of the 124 patients from one center who were reviewed in greater detail, pure cavernosal artery insufficiency (CAI) was found in 25 (20.2%), corporeal veno-occlusive dysfunction (CVOD) in 26 (21.0%), and 73 patients (58.9%) demonstrated combined CAI and CVOD. Diabetics (n = 69) achieved lower equilibrium intracorporeal pressures than nondiabetics, had similar CVOD, and worse CAI. Smokers (n = 365) and patients with Peyronie's disease (n = 32) had erectile dysfunction similar to those without these conditions. Patients impotent after trauma (n = 124) were younger, achieved higher intracorporeal pressures, and showed better corporeal veno-occlusive function than those without trauma. Complications of DICC were minimal and infrequent. After DICC, 169 patients underwent internal pudendal arteriography, 105 had arterial bypass surgery with or without penile venous ligation procedures, and 45 had venous surgery alone. Dynamic infusion cavernosometry and cavernosography is a useful erectile function study to evaluate impotence and can be performed easily in a private practice setting.
authors: Humana Impotence Research Study Group, Humana Hospitals, Aurora, Colorado.
authors: J M
authors: JM
authors: Kaufman
authors: F D
authors: FD
authors: Borges
authors: W P
authors: WP
authors: Fitch
authors: R A
authors: RA
authors: Geller
authors: M B
authors: MB
authors: Gruber
authors: J G
authors: JG
authors: Hubbard
authors: D L
authors: DL
authors: McKay
authors: J P
authors: JP
authors: Tuttle
authors: F R
authors: FR
authors: Witten
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D003925:Diabetic Angiopathies / Q000175:diagnosis; D007172:Erectile Dysfunction / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged; D010208:Papaverine; D010410:Penile Erection / Q000187:drug effects / Q000502:physiology*; D010411:Penile Induration / Q000175:diagnosis; D010413:Penis / Q000098:blood supply* / Q000000981:diagnostic imaging; D010646:Phentolamine; D011859:Radiography; D012039:Regional Blood Flow / Q000502:physiology; D012907:Smoking / Q000503:physiopathology; D014652:Vascular Diseases / Q000175:diagnosis
chemical_list: D010208:Papaverine; D010646:Phentolamine