T lymphocytes in pulmonary tuberculosis.
T cells and their sub-populations were evaluated with respect to reactive, intermediate and unreactive forms of tuberculosis as classified by Lenzini. Significant CD4 lymphopenia and a reduction of CD4/CD8 ratios were found in patients with reactive tuberculosis. It was observed that there was a B lymphocytosis, CD8 lymphocytosis and a reduction of CD4/CD8 ratio in patients with intermediate and unreactive forms of tuberculosis. The T lymphocytes and CD4 subset were unchanged. There was no significant difference in the lymphocytes and sub-populations among the intermediate and unreactive groups.
Ashtekar
M D
MD
Radiation Medicine Centre, Bhabha Atomic Research Centre, Bombay.
Samuel
A M
AM
Kadival
G V
GV
Sakhalkar
V
V
Rajadhyaksha
S
S
Virdi
S S
SS
D000328:Adult; D016516:CD4-CD8 Ratio; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D016176:T-Lymphocyte Subsets; D013601:T-Lymphocytes; D014391:Tuberculosis, Miliary / Q000276:immunology*; D014397:Tuberculosis, Pulmonary / Q000276:immunology*