title: Hemodynamics of a side-to-end proximal arterial anastomosis model.
abstract: OBJECTIVE
  The purpose of this article was to analyze the fluid mechanical effects of a side-to-end proximal anastomosis and to compare the results with those from our earlier study on the end-to-side distal anastomosis.
  
  
  METHODS
  The photochromic tracer technique was used to determine the instantaneous wall shear stress and to visualize the overall flow field under pulsatile flow conditions. The flow consisted of a sinusoid plus a steady component with mean and modulation Reynolds numbers of 355 and 565, respectively, and a Womersley number of 7.9.
  
  
  RESULTS
  At the toe and heel of the junction, very high and positive wall shear stresses were seen together with substantial nonperiodic fluctuations. The peak wall shear stress was about four times higher at the toe and about seven times higher at the heel than the maximum values observed at about four tube diameters upstream from the junction. On the bed of the host vessel, nonperiodic fluctuations were also observed, but the shear stresses were mainly negative with magnitudes comparable to those seen upstream. With leakages of 11% and 28% of the mean flow through the blocked end of the host vessel, the shear stress pattern seemed to be significantly affected only at the toe for the higher leakage. Further, when the mean Reynolds number was reduced to 320, the magnitudes of the variations in the wall shear stress were reduced proportionately, except at the heel, where the reduction was much larger than expected.
  
  
  CONCLUSIONS
  It appears that the preferential development of intimal hyperplasia at the distal end-to-side anastomosis may be promoted by low wall shear stress at the toe and heel, and probably by high shear stresses or shear stress gradients on the bed.
authors: Institute of Biomedical Engineering, University of Toronto, Ontario, Canada.
authors: M
authors: M
authors: Ojha
authors: R S
authors: RS
authors: Cobbold
authors: K W
authors: KW
authors: Johnston
mesh_terms: D000714:Anastomosis, Surgical; D001158:Arteries / Q000502:physiology* / Q000601:surgery*; D001783:Blood Flow Velocity; D004396:Coloring Agents; D006439:Hemodynamics; D006801:Humans; D007834:Lasers; D008955:Models, Cardiovascular; D008961:Models, Structural; D013314:Stress, Mechanical; D014466:Ultraviolet Rays
chemical_list: D004396:Coloring Agents