Successful treatment of sporotrichosis with oral fluconazole: a report of three cases.
We report three cases of sporotrichosis successfully treated with oral fluconazole. A verrucous lesion on the toe was cured after 126 days, and a lesion on the left foot resolved after 91 days' treatment. A case of lymphangitic-type sporotrichosis required 174 days of treatment to achieve a cure, and a higher dose (400 mg daily) was necessary in this case. Any side-effects were insignificant. We conclude that this new bis-triazole compound can be successfully used as an alternative treatment for sporotrichosis when conventional drugs must be avoided.
Castro
L G
LG
Department of Dermatology, University of São Paulo, Brazil.
Belda Júnior
W
W
Cucé
L C
LC
Sampaio
S A
SA
Stevens
D A
DA
D000284:Administration, Oral; D000328:Adult; D015725:Fluconazole / Q000627:therapeutic use*; D005533:Foot Dermatoses / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013174:Sporotrichosis / Q000188:drug therapy*
D015725:Fluconazole