title: Rubella vaccination and congenital rubella syndrome in Western Australia.
abstract: OBJECTIVE
  To review the incidence of congenital rubella syndrome (CRS) and the acceptance of schoolgirl rubella vaccination in Western Australia (WA), and to determine whether any groups in the community are at increased risk of having a child affected by CRS.
  
  
  METHODS
  Review of records of the WA Birth Defects Registry for cases of CRS; survey of obstetricians for terminations of pregnancy for maternal rubella infection; survey of schoolgirls eligible for the 1991 annual rubella vaccination campaign; review of Perth Immunisation Clinic and rural community and child health records; review of the rubella immune status of women tested antenatally.
  
  
  METHODS
  The incidence rate of CRS per 10,000 live births in WA 1980-1990; the incidence of rubella-associated terminations of pregnancy during 1990 and 1991; trends in rubella vaccine acceptance among WA schoolgirls between 1971 and 1991; and the proportion of women attending antenatal clinics who showed satisfactory immunity against rubella, stratified by country of birth.
  
  
  RESULTS
  The incidence rate of CRS in WA remains below 2 cases per 10,000 live births. Approximately 86% of Perth schoolgirls have been vaccinated against rubella. Rubella vaccine acceptance fell in some country areas during the late 1980s, but is now returning to acceptable levels. Women born in Asia are at greater risk of having a baby affected by CRS than women born in Australia. Babies with CRS may be born to women who have previously been vaccinated against rubella.
  
  
  CONCLUSIONS
  The incidence of CRS has fallen dramatically since the introduction of the schoolgirl vaccination program, but there is still a need for mechanisms to identify and vaccinate non-immune women.
authors: Health Department of Western Australia, East Perth.
authors: R J
authors: RJ
authors: Condon
authors: C
authors: C
authors: Bower
mesh_terms: D000028:Abortion, Induced / Q000706:statistics & numerical data; D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis; D001208:Asia / Q000208:ethnology; D004641:Emigration and Immigration; D005260:Female; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D010342:Patient Acceptance of Health Care; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology; D012409:Rubella / Q000517:prevention & control*; D012410:Rubella Syndrome, Congenital / Q000453:epidemiology* / Q000517:prevention & control; D012411:Rubella Vaccine; D012412:Rubella virus / Q000276:immunology; D014904:Western Australia / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral; D012411:Rubella Vaccine