title: Treatment failure of a single high dose of ivermectin for Mansonella perstans filariasis.
abstract: Infections with Mansonella perstans are common in certain parts of Africa and South America. There is no standard treatment at present. We evaluated the effect of a single high dose of ivermectin (600 micrograms/kg) on microfilaraemia in 7 consecutive patients. No decrease in microfilarial counts could be demonstrated after a follow-up period of 7-56 d.
authors: Institute for Tropical Medicine, Antwerp, Belgium.
authors: E
authors: E
authors: Van den Enden
authors: A
authors: A
authors: Van Gompel
authors: P
authors: P
authors: Van der Stuyft
authors: T
authors: T
authors: Vervoort
authors: J
authors: J
authors: Van den Ende
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008368:Mansonelliasis / Q000188:drug therapy*; D008842:Microfilariae; D008875:Middle Aged; D017211:Treatment Failure
chemical_list: D007559:Ivermectin