title: Autologous predonation, haemodilution and intraoperative blood salvage in elective abdominal aortic aneurysm repair.
abstract: The feasibility of predonated autologous blood transfusion and intraoperative blood salvage in elective abdominal aortic aneurysm repair was studied. Twenty consecutive patients were evaluated, of whom five were excluded according to protocol criteria. Patients each donated 1 unit blood 14 and 7 days before operation. A third unit was withdrawn in the anaesthetic room and replaced with Hartmann's solution, producing a haemodiluted state. Intraoperative losses were minimized using the Haemonetics Cell Saver III Plus autotransfusion system. Predonated blood from two patients passed its expiry date owing to repeated operation postponements, leaving 13 patients for study. The mean(s.d.) intraoperative blood loss was 700(300) ml with a mean(s.d.) intraoperative salvage of 420(300) ml. Two patients were transfused intraoperative salvage of 420(300) ml. Two patients were transfused according to clinical need. Thus nine patients safely avoided homologous transfusion. With autologous predonation, haemodilution and intraoperative blood salvage, elective aortic aneurysm repair can be performed safely with minimal need for homologous blood.
authors: Department of Surgery, Cheltenham General Hospital, Gloucestershire, UK.
authors: B R
authors: BR
authors: Tulloh
authors: C P
authors: CP
authors: Brakespear
authors: S C
authors: SC
authors: Bates
authors: D C
authors: DC
authors: Adams
authors: R G
authors: RG
authors: Dalton
authors: M J
authors: MJ
authors: Richards
authors: M A
authors: MA
authors: Durkin
authors: J B
authors: JB
authors: Bristol
authors: K R
authors: KR
authors: Poskitt
mesh_terms: D001012:Aorta, Abdominal / Q000601:surgery; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001804:Blood Transfusion, Autologous; D005240:Feasibility Studies; D006438:Hemodilution; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D011184:Postoperative Period
chemical_list: D006454:Hemoglobins