title: Quantification of aortic regurgitation by magnetic resonance velocity mapping.
abstract: The use of magnetic resonance (MR) velocity mapping in the quantification of aortic valvular blood flow was examined in 10 patients with angiographically verified aortic regurgitation. MR velocity mapping succeeded in identifying and quantifying the regurgitation in all patients, and the regurgitant volume determined with MR velocity mapping agreed well with the grade obtained by aortic root angiography (p < 0.02). The accuracy in quantification of the aortic valvular flow rate was demonstrated by a significant correlation between the stroke volume (ml) measured by MR velocity mapping and calculated from MR imaging of the left ventricular end-diastolic and end-systolic volumes in eight patients (Y = 0.89 x X + 11, r = 0.97, p < 0.001). This finding was confirmed by a good agreement between the net cardiac output (L/min) quantified with MR velocity mapping and simultaneous 125I-indicator dilution measurement in all subjects (Y = 0.89 x X + 0.08, r = 0.82, p < 0.01). In conclusion, MR velocity mapping may be used as a noninvasive tool in the quantification of aortic regurgitation.
authors: Danish Research Centre of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen.
authors: L
authors: L
authors: Søndergaard
authors: K
authors: K
authors: Lindvig
authors: P
authors: P
authors: Hildebrandt
authors: C
authors: C
authors: Thomsen
authors: F
authors: F
authors: Ståhlberg
authors: T
authors: T
authors: Joen
authors: O
authors: O
authors: Henriksen
mesh_terms: D000328:Adult; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000175:diagnosis* / Q000503:physiopathology; D001783:Blood Flow Velocity; D006328:Cardiac Catheterization; D005260:Female; D006801:Humans; D007201:Indicator Dilution Techniques; D007457:Iodine Radioisotopes; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009040:Motion Pictures; D016277:Ventricular Function, Left
chemical_list: D007457:Iodine Radioisotopes