title: [Analysis of the spatial structure of proteins in terms of residue-residue contacts. II. Contact affinity].
abstract: The possibility of detecting the mutual amino acid residue affinity when protein three-dimensional structures are described in terms of residue-residue contact matrices is discussed. The hypothesis of the lack of affinity between amino acid residues is examined; the values of the pertinent elements of the overall residue-residue contact matrices prove not to be statistically different from random estimates in 91%; the chance hypothesis is rejected in 9% of cases, represented as a rule by residues with charged side groups, especially oppositely charged ones.
authors: M A
authors: MA
authors: Rodionov
authors: A V
authors: AV
authors: Gurevich
authors: S G
authors: SG
authors: Galaktionov
mesh_terms: D000596:Amino Acids / Q000737:chemistry* / Q000378:metabolism; D001665:Binding Sites; D008956:Models, Chemical; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000596:Amino Acids; D011506:Proteins
vernacular_title: Analiz prostranstvennoĭ struktury belkov v terminakh matrits ostatok-ostatochnykh kontaktov. III. Srodstvo ostatkov.