title: [Regional cerebral blood flow in diabetic patients].
abstract: N-isopropyl-p-123I-iodoamphetamine (IMP) was used to quantify the regional cerebral blood flow (r-CBF) in 11 diabetic patients (average age; 67.9 years) and 12 non-diabetic subjects (average age; 67.4 years), none of whom had CVD (Cerebrovascular disease) on CT studies. A reference sampling method by continuous arterial blood sampling was used to quantify r-CBF. There were no significant differences in physiological or laboratory data between diabetic and non-diabetic groups except for fasting plasma glucose and HbA1C levels. The average of r-CBF in each region of cerebrum and cerebellum was significantly lower in diabetic group than that in the control group (p < 0.01). These observations show that r-CBF of diabetic patients is reduced, even in the absence of findings of CVD on a CT study.
authors: Department of Radiology, Nichinan Hospital of Miyazaki Prefecture.
authors: S
authors: S
authors: Nagamachi
authors: S
authors: S
authors: Ono
authors: T
authors: T
authors: Nishikawa
authors: M
authors: M
authors: Ageta
authors: T
authors: T
authors: Matsuo
authors: N
authors: N
authors: Kuroki
authors: S
authors: S
authors: Jinnouchi
authors: H
authors: H
authors: Hoshi
authors: S
authors: S
authors: Futami
authors: T
authors: T
authors: Ohnishi
mesh_terms: D000368:Aged; D000662:Amphetamines; D001921:Brain / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation; D003920:Diabetes Mellitus / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D008875:Middle Aged; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine