Behavioral evaluating methods in the objective clinical assessment of motor function after experimental brachial plexus reconstruction in the rat.
Unfortunately, the results of brachial plexus surgery have not fulfilled expectations. Although the components of the rat brachial plexus are similar to those of the human plexus, experimental work in this field is limited. No functional test to assess experimental brachial plexus reconstruction has so far been published. We worked out a method of evaluating brachial plexus impairment in rats in the laboratory. It consists of a simple test in which a bowl of water is projected over the animal's head, eliciting grooming movements of the forepaws towards the head. This test is therefore called the 'grooming test'. A system of scoring the animals' performance is suggested. Rats were also submitted to walking tracks analysis, but this was of limited value in assessing brachial plexus impairment.
Bertelli
J A
JA
Laboratoire de Neurobiologie, Université René Descartes, Paris, France.
Mira
J C
JC
D000818:Animals; D001522:Behavior, Animal; D001917:Brachial Plexus / Q000503:physiopathology* / Q000601:surgery; D003714:Denervation; D004550:Elbow / Q000503:physiopathology; D006120:Grooming; D008026:Ligation; D009043:Motor Activity / Q000502:physiology*; D009132:Muscles / Q000294:innervation; D009333:Neck; D011184:Postoperative Period; D051381:Rats; D012867:Skin / Q000294:innervation; D013126:Spinal Nerve Roots; D016138:Walking