[Pleural washing with povidone-iodine for treatment of empyema].
In this paper, we report two successful cases of empyema treated by pleural washing with povidone-iodine solution. In these two cases, empyema was caused by secondary infection of multi-drug resistant Pseudomonas aeruginosa. First, we replaced intrathoracic drainage tube and washed intrathoracic space with 500-1000 ml saline containing antibiotics (tobramycin, aztreonam) every 8 hours for 10-14 days. But, cultural studies of pleural effusion were positive even after this treatment. So, we tried pleural washing with warm povidone-iodine solution 1:20 diluted with saline every 8 hours. Surprisingly, after 3 days treatment, cultural studies of the pleural effusion became negative. This pleural washing method with povidone-iodine was very effective for treatment of empyema patients.
Takayama
K
K
Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University.
Hirata
M
M
Nabeshima
S
S
Nabeshima
A
A
Hara
H
H
Kashiwagi
S
S
D000368:Aged; D016724:Empyema, Pleural / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011206:Povidone-Iodine / Q000627:therapeutic use*; D011552:Pseudomonas Infections / Q000628:therapy; D015163:Superinfection / Q000628:therapy; D007507:Therapeutic Irrigation / Q000379:methods*
D011206:Povidone-Iodine