The influence of portoenterostomy with stoma on morbidity in pediatric patients with biliary atresia undergoing orthotopic liver transplantation.
A portoenterostomy (PE) procedure for extrahepatic biliary atresia (EHBA) is sometimes performed with a stoma in an attempt to reduce the incidence of acute cholangitis. The purpose of this study was to determine if the presence of a stoma increased the complication rate of patients undergoing orthotopic liver transplantation (OLT) for EHBA. The medical records of 42 consecutive patients with EHBA who underwent primary OLT between October 1988 and October 1991 were retrospectively reviewed. Three patients were excluded, since their grafts were lost within 3 days of OLT. The remaining 39 patients were divided into three groups: no PE (n = 7), PE without stoma (n = 23), and PE with stoma (n = 9). The mean age of the whole group was 19.62 +/- 24.37 months, with a range of 5 to 132 months. Mean weight was 9.62 kg, with a range of 4.2 to 41 kg. Survival at 3 and 12 months as well as number of retransplantations were similar among the three groups. However, at the time of OLT increased morbidity was observed, consisting of increased operative time and number of reoperations, whether or not the stoma had been closed prior to OLT.
Meister
R K
RK
Department of Transplantation, California Pacific Medical Center, San Francisco.
Esquivel
C O
CO
Cox
K L
KL
Concepcion
W
W
Berquist
W
W
Nakazato
P
P
deVries
P A
PA
D001656:Biliary Atresia / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D004766:Enterostomy; D006801:Humans; D007223:Infant; D016031:Liver Transplantation; D009017:Morbidity; D011171:Portoenterostomy, Hepatic / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology*; D012086:Reoperation; D012189:Retrospective Studies