title: Electron-microscopic observation of a human epidermal Langerhans cell in mitosis.
abstract: Langerhans cells are dendritic cells of the epidermis originating from bone marrow precursors which may exceptionally undergo mitosis within the skin. We report herein an electron-microscopic observation of a dividing LC within a seemingly hyperproliferative human epidermis. This observation further underlines the self-reproducing capacity of LC in situ and suggests that LC may respond to the same mitogenic stimuli as keratinocytes.
authors: Lab. of Dermatopathology/INSERM U346, Hôp. Ed. Herriot, Lyon, France.
authors: J
authors: J
authors: Kanitakis
authors: E
authors: E
authors: Hoyo
authors: C
authors: C
authors: Perrin
authors: D
authors: D
authors: Schmitt
mesh_terms: D002648:Child; D004817:Epidermis / Q000473:pathology; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000473:pathology*; D007801:Langerhans Cells / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008938:Mitosis