Fluoxetine treatment of depression caused by interferon-alpha.
Interferon-alpha is the only approved and effective treatment for hepatitis C. Psychiatric side effects are common and have frequently required a decrease in dose or discontinuation of therapy. We here report a case of interferon-alpha-induced depression in a 40-yr-old man with hepatitis C successfully treated with the antidepressant fluoxetine, which allowed completion of interferon treatment.
Levenson
J L
JL
Department of Psychiatry, Medical College of Virginia Hospitals, Virginia Commonwealth University, Richmond.
Fallon
H J
HJ
D000328:Adult; D003863:Depression / Q000188:drug therapy* / Q000209:etiology*; D005473:Fluoxetine / Q000627:therapeutic use*; D006526:Hepatitis C / Q000628:therapy; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D011994:Recombinant Proteins
D007370:Interferon Type I; D011994:Recombinant Proteins; D005473:Fluoxetine