title: In vivo evidence of all-trans retinoic acid inducing maturation in acute promyelocytic leukaemia.
abstract: All-trans retinoic acid therapy induces maturation in acute promyelocytic leukaemia. We document in vivo evidence of differentiation by all-trans retinoic acid in a case of acute promyelocytic leukaemia which was characterized by cytoplasmic vacuolations.
authors: Haematology Unit, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur.
authors: H N
authors: HN
authors: Hamidah
authors: S K
authors: SK
authors: Cheong
authors: O
authors: O
authors: Ainoon
mesh_terms: D001853:Bone Marrow / Q000648:ultrastructure; D002454:Cell Differentiation; D005260:Female; D006098:Granulocytes / Q000648:ultrastructure; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D014212:Tretinoin / Q000627:therapeutic use*; D014617:Vacuoles / Q000473:pathology
chemical_list: D014212:Tretinoin