title: Familial systemic lupus erythematosus characterized by digital ischemia.
abstract: We describe a family in which 3 members each developed systemic lupus erythematosus complicated by ischemic vasculopathy. The calendar years and patient ages of disease onset and the clinical courses were remarkably similar for all 3 patients, although their genotypes were not. The potential contributions of heredity and environment to the concordance of disease expression in this family are discussed.
authors: Department of Medicine, University of Saskatchewan, Saskatoon, Canada.
authors: J T
authors: JT
authors: Sibley
authors: K L
authors: KL
authors: Blocka
authors: D P
authors: DP
authors: Sheridan
authors: W P
authors: WP
authors: Olszynski
mesh_terms: D000328:Adult; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000150:complications* / Q000235:genetics* / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000235:genetics* / Q000276:immunology; D008297:Male; D014034:Toes / Q000098:blood supply*