Unusual lymphangioma observed prenatally in a 45,X fetus.
We present a case of a large frontal lesion, suspected on antenatal ultrasound to be a cephalocele. The cardiac anatomy was abnormal and fetal blood sampling showed a 45,X chromosome constitution. Postmortem examination proved this to be a lymphangioma and confirmed the presence of a cardiac defect. We suggest that this lymphangioma represents an unusual manifestation of monosomy X and discuss the importance of doing chromosome analysis in the presence of such a lesion which is of similar appearance as a cephalocele.
Haeusler
M C
MC
Department of Fetal Medicine, University College Hospital, London, United Kingdom.
Ryan
G
G
Sams
V
V
Robson
S C
SC
Young
M
M
Sullivan
I D
ID
Lipitz
S
S
Rodeck
C H
CH
D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008202:Lymphangioma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology; D009006:Monosomy; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012535:Scalp; D012878:Skin Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology; D014463:Ultrasonography; D014960:X Chromosome