AB023, novel polyene antibiotics. II. Isolation and structure determination.
AB023, a complex of new polyene antibiotics, was isolated from a soil Streptomyces strain. The two main components, pentaene antibiotics AB023a and AB023b, were separated and purified by preparative chromatographic methods and their structures were determined by extensive NMR and mass spectrometric studies.
Bortolo
R
R
Istituto Guido Donegani, ENICHEM, Novara, Italy.
Spera
S
S
Gugliemetti
G
G
Cassani
G
G
D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D011090:Polyenes / Q000737:chemistry / Q000302:isolation & purification; D013302:Streptomyces / Q000378:metabolism*
D000935:Antifungal Agents; D007783:Lactones; D011090:Polyenes