title: Successful treatment of sporotrichosis with oral fluconazole: a report of three cases.
abstract: We report three cases of sporotrichosis successfully treated with oral fluconazole. A verrucous lesion on the toe was cured after 126 days, and a lesion on the left foot resolved after 91 days' treatment. A case of lymphangitic-type sporotrichosis required 174 days of treatment to achieve a cure, and a higher dose (400 mg daily) was necessary in this case. Any side-effects were insignificant. We conclude that this new bis-triazole compound can be successfully used as an alternative treatment for sporotrichosis when conventional drugs must be avoided.
authors: Department of Dermatology, University of São Paulo, Brazil.
authors: L G
authors: LG
authors: Castro
authors: W
authors: W
authors: Belda Júnior
authors: L C
authors: LC
authors: Cucé
authors: S A
authors: SA
authors: Sampaio
authors: D A
authors: DA
authors: Stevens
mesh_terms: D000284:Administration, Oral; D000328:Adult; D015725:Fluconazole / Q000627:therapeutic use*; D005533:Foot Dermatoses / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013174:Sporotrichosis / Q000188:drug therapy*
chemical_list: D015725:Fluconazole