The efficacy of Na-naproxen after diagnostic and therapeutic arthroscopy of the knee joint.
The purpose of the study was to evaluate the effect of na-naproxen after diagnostic arthroscopy and arthroscopic surgery of the knee joint. In a double-blind trial, 41 patients were randomized to treatment with na-naproxen, and 46 patients were given placebo after surgery. For additional analgesia, patients got acetaminophen if necessary. In patients who underwent arthroscopic surgery, there were no differences between those treated with na-naproxen and those who received placebo in pain levels, but patients receiving na-naproxen had significantly less need for additional analgesia and returned significantly more quickly to work than patients receiving placebo (median 10 versus 30 days). In patients who had only diagnostic arthroscopy, there were no differences between the na-naproxen and placebo groups.
Pedersen
P
P
Department of Orthopedic Surgery, Odense University Hospital, Denmark.
Nielsen
K D
KD
Jensen
P E
PE
D000082:Acetaminophen / Q000627:therapeutic use; D000328:Adult; D001182:Arthroscopy; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D009288:Naproxen / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000517:prevention & control*
D000082:Acetaminophen; D009288:Naproxen