title: [The effect of elymoclavine and its derivatives on various enzymes of the gastrointestinal tract].
abstract: The influence of elymoclavine, elymoclavine hydrochloride, elymoclavine hydrobromide, 2-bromelymoclavine, 2-bromelymoclavine hydrobromide on the initial rater of enzymatic hydrolysis of cytidine-2',3'-monophosphate by RNase A and of N-alpha-benzoyl-DL-tyrosine-p-nitroanilide by alpha-chymotrypsin has been investigated. It is shown that all the compounds have the features of various types of inhibitors of RNase A and alpha-chymotrypsin with the exception of elymoclavine which shows all features of a catalytic activator of RNase A.
authors: A I
authors: AI
authors: Kudriavtseva
authors: M U
authors: MU
authors: Arinbasarov
authors: A G
authors: AG
authors: Kozlovskiĭ
authors: V I
authors: VI
authors: Krupianko
mesh_terms: D000818:Animals; D002384:Catalysis; D002417:Cattle; D002918:Chymotrypsin / Q000037:antagonists & inhibitors*; D004064:Digestive System / Q000201:enzymology*; D004789:Enzyme Activation; D004873:Ergolines / Q000737:chemistry / Q000494:pharmacology*; D006868:Hydrolysis; D012259:Ribonuclease, Pancreatic / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D004873:Ergolines; C007586:elymoclavine; D012259:Ribonuclease, Pancreatic; D002918:Chymotrypsin
vernacular_title: Vliianie élimoklavina i ego proizvodnykh na nekotorye fermenty zheludochno-kishechnogo trakta.