title: Orbital infarction syndrome.
abstract: BACKGROUND
  The authors define orbital infarction as ischemia of all intraorbital and intraocular structures. It is a rare disorder due to the rich anastomotic vascularization of the orbit.
  
  
  METHODS
  The authors report three patients with orbital infarction with similar clinical presentations: acute blindness, orbital pain, total ophthalmoplegia, and anterior and posterior segment ischemia.
  
  
  RESULTS
  Etiologies of orbital infraction syndrome include occlusion of the common carotid artery (case 1), giant-cell arteritis (case 2), and mucormycosis (case 3).
  
  
  CONCLUSIONS
  Three cases discussed in this article illustrate that orbital infarction is a disorder that can occur secondary to different mechanisms such as (1) acute perfusion failure (e.g., common carotid artery occlusion [possibly combined with anomalous orbital anastomotic channels]), 2) systemic vasculitis (e.g., giant-cell arteritis), and (3) orbital cellulitis with vasculitis (mucormycosis). The blindness and retinal and optic nerve damage were permanent, whereas the other signs of orbital ischemia (ophthalmoplegia and anterior segment ischemia) resolved. Therefore, diagnosis of orbital infarction can best be made during the acute phase.
authors: Hôpital Ophtalmique Jules Gonin, University Eye Clinic, Lausanne, Switzerland.
authors: F X
authors: FX
authors: Borruat
authors: J
authors: J
authors: Bogousslavsky
authors: S
authors: S
authors: Uffer
authors: G
authors: G
authors: Klainguti
authors: N J
authors: NJ
authors: Schatz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001766:Blindness / Q000209:etiology; D016893:Carotid Stenosis / Q000150:complications; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D013700:Giant Cell Arteritis / Q000150:complications; D006801:Humans; D007238:Infarction / Q000150:complications / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications; D009915:Orbit / Q000098:blood supply*; D013577:Syndrome; D014057:Tomography, X-Ray Computed