Current treatment modalities for symptomatic gallstones.
Gallstone disease is an important clinical problem: approximately 10% of all adults in the western population have gallstones. Most gallstones, however, remain asymptomatic, and from various disciplines there is consensus that only symptomatic gallstones require therapy. Since the first gallbladder extirpation in 1882, cholecystectomy has been considered the gold standard. Nowadays, this operation is performed laparoscopically in most hospitals. Despite relatively low morbidity and mortality rates, a number of alternative therapies have been developed in the past few years. These alternative treatment modalities are especially indicated in high risk patients and in patients rejecting surgery. In this review article, the currently available treatment modalities are discussed.
Plaisier
P W
PW
Department of General Surgery, University Hospital, Erasmus University Rotterdam, The Netherlands.
van der Hul
R L
RL
Terpstra
O T
OT
Bruining
H A
HA
D002635:Chenodeoxycholic Acid / Q000627:therapeutic use; D002763:Cholecystectomy; D017081:Cholecystectomy, Laparoscopic; D002769:Cholelithiasis / Q000628:therapy*; D004987:Ethers / Q000627:therapeutic use; D006801:Humans; D008096:Lithotripsy; D008738:Methyl Ethers; D012997:Solvents / Q000627:therapeutic use; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
D004987:Ethers; D008738:Methyl Ethers; D012997:Solvents; D002635:Chenodeoxycholic Acid; C043243:methyl tert-butyl ether; D014580:Ursodeoxycholic Acid