title: Effect of rinsing time on antiplaque-antigingivitis efficacy of listerine.
abstract: This double-blind, controlled clinical study compared the effectiveness of 30- and 60-s listerine rinses in both inhibiting the development of, and reducing existing, supragingival plaque and gingivitis, using an experimental gingivitis model. 94 subjects completed this study. For each subject, a modified gingival index, modified Quigley-Hein plaque index and Eastman interdental bleeding index were recorded at baseline and at 2 weeks. Following the baseline examinations, subjects received half-mouth prophylaxes, and began 2 x daily supervised rinsing either with listerine for 30 or 60 s or with a control mouthrinse for 30 s as their sole oral hygiene measure. Statistical analysis (ANCOVA) showed that both the 30- and 60-s listerine rinses were significantly (p < 0.01) more effective than the control in inhibiting and reducing plaque, gingivitis and gingival bleeding. Although 60-s rinses with listerine were significantly more effective (p < 0.01) than 30-s rinses in controlling plaque, the 2 rinse durations were similarly effective in controlling interdental bleeding and gingivitis. This study confirms the recommendation of 2x daily rinsing with listerine for 30 s as an effective regimen for gingivitis control.
authors: Hazleton Florida, Inc., West Palm Beach.
authors: N M
authors: NM
authors: Ross
authors: S M
authors: SM
authors: Mankodi
authors: K L
authors: KL
authors: Mostler
authors: C H
authors: CH
authors: Charles
authors: L L
authors: LL
authors: Bartels
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D003773:Dental Plaque / Q000188:drug therapy*; D003774:Dental Plaque Index; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D005891:Gingivitis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000008:administration & dosage / Q000627:therapeutic use*; D009910:Oral Hygiene / Q000379:methods; D010512:Periodontal Index; D012459:Salicylates / Q000008:administration & dosage / Q000627:therapeutic use*; D013729:Terpenes / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D009067:Mouthwashes; D012459:Salicylates; D013729:Terpenes; C057473:Listerine