Pooled outcome measures in arthritis: the pros and cons.
This article considers the implications of reporting multiple measures of efficacy in studies of patients with rheumatoid arthritis (RA). A possible solution to the problems that result is the use of a pooled index which combines the individual outcome measures. The potential advantages and disadvantages of pooled indexes are discussed in the context of clinical trials in RA.
Roberts
R S
RS
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.
D001172:Arthritis, Rheumatoid / Q000628:therapy*; D002986:Clinical Trials as Topic; D006801:Humans; D012720:Severity of Illness Index; D016896:Treatment Outcome