title: Congenital adrenal hyperplasia with testicular tumors, aggression, and gonadal failure.
abstract: Bilateral testicular tumors (adrenal rests) may occur in untreated or poorly controlled congenital adrenal hyperplasia. This case report describes two unique associated phenomena: (1) psychologic disturbances similar to those seen with exogenous androgen abuse, which resolved with appropriate glucocorticoid suppression of androgen over-production by this abnormal adrenal/adrenal rest tissue; and (2) testicular failure which showed a partial, delayed recovery with corticosteroid therapy. The need for a careful history and biochemical screening for all patients with bilateral testicular tumors is reinforced.
authors: Department of Medicine, University of Manitoba, Winnipeg, Canada.
authors: E J
authors: EJ
authors: Keely
authors: I
authors: I
authors: Matwijiw
authors: J A
authors: JA
authors: Thliveris
authors: C
authors: C
authors: Faiman
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000150:complications*; D000314:Adrenal Rest Tumor / Q000150:complications; D000328:Adult; D000374:Aggression; D006801:Humans; D008297:Male; D013736:Testicular Neoplasms / Q000150:complications*; D013737:Testis / Q000503:physiopathology*