title: A new method of blood sampling and determination of the local anesthetic agent lidocaine in dentistry.
abstract: Blood levels of local anesthetic agents after application in dentistry have been determined only in peripheral venous blood. A method of withdrawing blood from the alveolus after extraction of a tooth was developed. With a new simple gas chromatographic method with a low detection limit, concentration of lidocaine was determined. A correlation between the blood levels of lidocaine and the type of anesthesia and the localization of the extracted teeth was found.
authors: Institute of Clinical Pharmacology, Medical Academy C.G. Carus, Dresden, FRG.
authors: R
authors: R
authors: Oertel
authors: A
authors: A
authors: Oertel
authors: K
authors: K
authors: Feller
mesh_terms: D000698:Analgesia; D002849:Chromatography, Gas; D006801:Humans; D008012:Lidocaine / Q000097:blood*; D014081:Tooth Extraction
chemical_list: D008012:Lidocaine