Haemophilus influenzae type b disease in north-west England.
A study was made in the north-west of England during 1989 in order to ascertain the incidence of serious Haemophilus influenzae infection, its short-term morbidity and certain characteristics of treatment. The incidence of culture-proven infection was 28 per 100,000 children under 5 years of age. Case fatality was 3%, one of the deaths being in a 6-year-old child. Some of the information obtained will help to assess the cost-effectiveness of the new vaccine to be administered to children in the U.K. The mean length of stay in hospital for all cases was 10 days. Of a total of 87 patients, 20 (23%) were admitted to an intensive therapy unit while five were transferred from a district general hospital to a regional paediatric unit. The estimated average cost per episode of acute care was 2700 pounds. Antibiotic regimens varied considerably.
Quigley
C
C
Manchester Public Health Laboratory, University Hospital of South Manchester, Withington, U.K.
Kaczmarski
E B
EB
Jones
D M
DM
Haycox
A R
AR
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004739:England / Q000453:epidemiology; D005260:Female; D006192:Haemophilus Infections / Q000150:complications / Q000191:economics / Q000453:epidemiology* / Q000628:therapy; D006193:Haemophilus influenzae; D017048:Health Care Costs; D006760:Hospitalization / Q000191:economics; D006801:Humans; D015994:Incidence; D007223:Infant; D007362:Intensive Care Units / Q000191:economics; D008297:Male; D009017:Morbidity
D000900:Anti-Bacterial Agents