Acute tumour lysis syndrome.
Acute tumour lysis syndrome results from a rapid massive release of cellular breakdown products consequent upon tumour cell death following effective therapy. This may overwhelm normal excretory mechanisms, resulting in metabolic disturbance which can lead to sudden death or prolonged morbidity from renal impairment.
Chasty
R C
RC
University Department of Clinical Haematology, Manchester Royal Infirmary.
Liu-Yin
J A
JA
D000208:Acute Disease; D006801:Humans; D051437:Renal Insufficiency / Q000209:etiology; D015275:Tumor Lysis Syndrome / Q000503:physiopathology / Q000628:therapy