title: Conservative surgery and radiation therapy in early breast cancer: ten-year experience at the West Florida Cancer Institute.
abstract: Between July 1981 and December 1989, 143 patients received conservative surgery and radiation for 147 primary breast tumors. Ten lesions were staged as Tis, 122 as T1, and 15 as T2. N stages were NX in 15 cases, N0 in 93, and N1 in 39. All patients had lumpectomy, and 132 (89%) had axillary lymph node dissection. All had irradiation (45 to 50 Gy) to the entire breast. All received an electron boost to the primary site to a total dose of 60 Gy. Minimal follow-up was 18 months, and median follow-up was 56 months; 123 patients had at least 3 years of follow-up, and 59 patients had at least 5 years. The local control rates at 3 and 5 years were 96% and 97%, respectively. Tumor-free states at 3 and 5 years were 93% and 86%, respectively. Minor complications occurred in four patients. Approximately 90% of patients had good to excellent cosmetic results.
authors: Department of Radiation Oncology, West Florida Cancer Institute, Pensacola 32514.
authors: E H
authors: EH
authors: Amos
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local