[The nature of the emergence of His+-revertants in Salmonella typhimurium].
The His(-)-->His+ spontaneous reversion of the Salmonella typhimurium alleles hisD3052 and hisG46 was studied. The expected jackpot distribution of His+ revertants was not observed in the fluctuation tests. The experimental distributions were close to Poisson. It was also shown that the mean number of His+ reversion events and the mean number of revertants per plate were similar. These data demonstrate that the His+ reversion occurred under the influence of histidine starvation. At the same time, kanamycin resistant mutants had the jackpot distribution. Selection for His+ revertants did not increase the Kans-->Kanr mutations.
Gizatullin
F Sh
FSh
Lezin
G T
GT
Lomovtseva
E Iu
EIu
Babynin
E V
EV
D005798:Genes, Bacterial; D006639:Histidine / Q000235:genetics*; D009154:Mutation; D012486:Salmonella typhimurium / Q000235:genetics*
D006639:Histidine
K prirode vozniknoveniia His+-revertantov u Salmonella typhimurium.