Allergic contact dermatitis of the lip margins from para-tertiary-butylphenol in a lip liner.
We describe the use of gas chromatography with mass spectrometry (GC-MS) in the investigation of a case of allergic contact dermatitis of the lip margins caused by a lip liner. Patch testing identified sensitization to para-tertiary-butylphenol-formaldehyde resin (PTBP-FR), a resin glue frequently used in leather work but rarely found in cosmetics. Investigation specified the para-tertiary-butylphenol (PTBP) component of the resin as the hapten responsible for the allergic contact dermatitis, as well as for associated depigmentation.
Angelini
E
E
Istituto di Dermatologia e Venereologia, Università degli Studi di Roma Tor Vergata, Rome, Italy.
Marinaro
C
C
Carrozzo
A M
AM
Bianchi
L
L
Delogu
A
A
Giannello
G
G
Nini
G
G
D000328:Adult; D003358:Cosmetics / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008047:Lip Diseases / Q000139:chemically induced*; D010636:Phenols / Q000009:adverse effects* / Q000032:analysis
D003358:Cosmetics; D010636:Phenols; C006862:butylphen