Effect of hyperbaric oxygen therapy on osseointegration of titanium implants in irradiated bone: a preliminary report.
Four patients who had undergone combined surgical and radiotherapeutic treatment for maxillofacial cancer had osseointegrated titanium implants placed in the bone of the treated region at various intervals after irradiation. Preoperatively and postoperatively, hyperbaric oxygen therapy was administered to the patients at the level of 2 or 3 atmosphere absolute (ATA). Of the 21 fixtures placed, one was lost because of lack of osseointegration, rendering the survival rate 92.3%. Hyperbaric oxygen therapy seemed to be a viable method to improve the survival rate of fixtures in irradiated bone tissue.
Ueda
M
M
Department of Oral Surgery, Nagoya University Hospital, Japan.
Kaneda
T
T
Takahashi
H
H
D000368:Aged; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008334:Mandible / Q000528:radiation effects / Q000601:surgery; D008437:Maxilla / Q000528:radiation effects* / Q000601:surgery; D008441:Maxillary Neoplasms / Q000532:radiotherapy / Q000601:surgery; D008447:Maxillofacial Prosthesis; D008875:Middle Aged; D009060:Mouth Floor; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000601:surgery; D016348:Osseointegration; D019736:Prostheses and Implants; D011475:Prosthesis Failure; D011832:Radiation Injuries / Q000628:therapy*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects; D014025:Titanium; D014945:Wound Healing
D014025:Titanium