Neurological findings in newborn infants after extracorporeal membrane oxygenation, with special reference to the EEG.
Seventeen newborn infants were treated with extracorporeal membrane oxygenation (ECMO). Two died shortly after the start of ECMO due to the underlying disease, two died later in the course due to a lack of recovery of lung function and two others died weeks after ECMO from renal damage and a cardiac defect. Of the survivors, nine are developing normally (aged between one and four years) and two are severely disabled because of infarctions of the left hemisphere, acquired before and after ECMO. Intermittent-discontinuous EEGs did not indicate a poor prognosis if normalization of the EEG occurred within seven days. However, infarcted areas on ultrasonography, persistent EEG changes or deteriorating findings indicated disability or early death.
Korinthenberg
R
R
Department of Neuropediatrics and Muscular Diseases, Pediatric University Hospital Freiburg, Germany.
Kachel
W
W
Koelfen
W
W
Schultze
C
C
Varnholt
V
V
D001921:Brain / Q000098:blood supply; D001927:Brain Diseases / Q000188:drug therapy / Q000209:etiology; D004569:Electroencephalography; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008168:Lung / Q000503:physiopathology; D008171:Lung Diseases / Q000150:complications / Q000503:physiopathology; D008297:Male; D009020:Morphine / Q000627:therapeutic use; D009026:Mortality; D011665:Pulmonary Valve Insufficiency / Q000150:complications / Q000628:therapy*
D009020:Morphine