title: Delivery of constant air-oxygen mixtures using a closed circle absorber system.
abstract: The aim of this study was to devise and validate a technique to deliver constant air-oxygen mixtures from a standard anaesthetic machine using only oxygen as the compressed gas source. The common gas outlet was modified to allow measured quantities of ambient air to be insufflated via a three-way attachment into a closed circle absorber system with a double-circuit collapsible bellows ventilator. During positive pressure ventilation, leakages of between 50-150 ml.min-1 occur from the circuit and nomograms of the minimal air and oxygen flow rates needed to maintain constant oxygen concentrations in the presence of the leaks were then mathematically derived. The accuracy of the nomograms was tested on three different anaesthetic machines using test lung models. There were no differences observed among the mean oxygen concentrations using the three machines. Pooled mean values (SD) of 30.65% (0.77), 51.07% (1.04) and 70.4% (0.73) were obtained for predicted inspired concentrations of 30, 50 and 70% respectively. Next, the technique was studied on 18 patients who underwent isoflurane or propofol anaesthesia (duration 40-210 min) for various surgical procedures. Pooled mean values (SD) obtained were 29.3% (1.86), 40.95% (1.65) and 50.06% (1.41) respectively for predicted oxygen concentrations of 30, 40 and 50% respectively. We conclude that this technique can be used to deliver constant air-oxygen mixtures accurately during inhalational or total intravenous anaesthesia when N2O is contraindicated but a source of compressed air is not readily available.
authors: Department of Anaesthesia, Tan Tock Seng Hospital, Singapore.
authors: T W
authors: TW
authors: Lew
authors: W M
authors: WM
authors: San
authors: M K
authors: MK
authors: Chin
mesh_terms: D000328:Adult; D000388:Air; D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation* / Q000379:methods; D002245:Carbon Dioxide / Q000032:analysis; D004867:Equipment Design; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage; D008168:Lung / Q000502:physiology; D008954:Models, Biological; D008991:Monitoring, Physiologic; D009294:Narcotics / Q000008:administration & dosage; D010100:Oxygen / Q000008:administration & dosage*; D010101:Oxygen Consumption / Q000502:physiology; D011312:Pressure; D015203:Reproducibility of Results; D012121:Respiration, Artificial; D012212:Rheology
chemical_list: D009294:Narcotics; D002245:Carbon Dioxide; D007530:Isoflurane; D010100:Oxygen