Absence of linkage between chromosome 21 loci and familial amyotrophic lateral sclerosis.
Familial amyotrophic lateral sclerosis (FALS) has recently been shown to be linked to chromosome 21 markers in a subset of families. However, we were unable to show linkage between FALS and chromosome 21 markers which flank the putative FALS locus in UK families.
King
A
A
Department of Biochemistry, Charing Cross and Westminister Medical School, London.
Houlden
H
H
Hardy
J
J
Lane
R
R
Chancellor
A
A
de Belleroche
J
J
D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics*; D002891:Chromosomes, Human, Pair 21; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D006113:United Kingdom
D005819:Genetic Markers