[A case of Down's syndrome with progressive dementia of Alzheimer type].
A rare case of Down's syndrome complicated with progressive dementia of Alzheimer type in a 41-year-old man was reported. On 123I-IMP SPECT, the patient revealed symmetrical bilateral temporo-parietal hypoperfusion. This finding seemed to support the developing dementia of Alzheimer type on the basis of clinical manifestations. 123I-IMP SPECT seemed to be useful for early diagnosis of Alzheimer-like change in a natural course of Down's syndrome.
Ishino
Y
Y
Department of Radiology, University of Occupational and Environmental Health, School of Medicine.
Mori
T
T
Nakata
H
H
D000328:Adult; D000544:Alzheimer Disease / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D000662:Amphetamines; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D004314:Down Syndrome / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D015899:Tomography, Emission-Computed, Single-Photon
D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine