title: Efficacy and causes of failure of endoscopic subureteric injection of Teflon in the treatment of primary vesicoureteric reflux.
abstract: A total of 135 consecutive patients with primary vesicoureteric reflux (VUR) were treated as day cases using submucosal Teflon injection (STING) between 1984 and 1988. Up to 3 repeat procedures were performed in the event of failure; 89% of patients and 92% of ureters were cured. None was obstructed and 2 recurred. Eight patients continue to have asymptomatic reflux Grade 2 or less, while 7 have had open surgery to correct the reflux. Most of the failures had a satisfactory appearance at STING but this deteriorated with time and appears to have been caused by leakage of Teflon from the injection site post-operatively. There were no signs or symptoms of embolisation or migration of the implant material.
authors: Northern Ireland Paediatric Surgical Service, Royal Belfast Hospital for Sick Children.
authors: H A
authors: HA
authors: Bhatti
authors: H
authors: H
authors: Khattak
authors: V E
authors: VE
authors: Boston
mesh_terms: D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007267:Injections; D008297:Male; D011138:Polytetrafluoroethylene / Q000008:administration & dosage*; D019736:Prostheses and Implants; D011859:Radiography; D012086:Reoperation; D017211:Treatment Failure; D014513:Ureter / Q000601:surgery; D001743:Urinary Bladder / Q000601:surgery; D014718:Vesico-Ureteral Reflux / Q000000981:diagnostic imaging / Q000628:therapy*
chemical_list: D011138:Polytetrafluoroethylene