Complications and risk factors after ileal pouch-anal anastomosis for ulcerative colitis associated with primary sclerosing cholangitis.
OBJECTIVE
This study determined predictive factors for postoperative complications and outcome after ileal pouch-anal anastomosis in patients with ulcerative colitis and primary sclerosing cholangitis.


BACKGROUND
Patients with ulcerative colitis and primary sclerosing cholangitis treated by colectomy and ileostomy are at high risk of troublesome bleeding from peristomal varices.


METHODS
Postoperative complications and outcome were assessed in 40 patients with ulcerative colitis and sclerosing cholangitis who received an ileal pouch-anal anastomosis between January 1981 and February 1990.


RESULTS
Immediate postoperative and remote ileoanal anastomosis-related complications were high but related directly to the severity of liver disease. No patient had perianastomotic anal bleeding.


CONCLUSIONS
In patients with both ulcerative colitis and primary sclerosing cholangitis, ileal pouch-anal anastomosis is safe and is not associated with perianastomotic bleeding.
Kartheuser
A H
AH
Section of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota.
Dozois
R R
RR
Wiesner
R H
RH
LaRusso
N F
NF
Ilstrup
D M
DM
Schleck
C D
CD
D000328:Adult; D001003:Anal Canal / Q000098:blood supply; D001803:Blood Transfusion; D015209:Cholangitis, Sclerosing / Q000150:complications*; D003082:Colectomy; D003093:Colitis, Ulcerative / Q000150:complications* / Q000601:surgery*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D009017:Morbidity; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology; D016737:Proctocolectomy, Restorative / Q000009:adverse effects*; D012307:Risk Factors; D013997:Time Factors; D014648:Varicose Veins / Q000453:epidemiology