title: Spatial dose-rate distribution for an 194Ir point source in water.
abstract: The spatial dose-rate distribution arising from a unit activity point source of 194Ir embedded in an infinite water medium has been calculated. These results may prove to be both useful and timely; 194Ir is a beta-particle-emitting radionuclide that is a suitable candidate for radioimmunotherapy, and a means for producing it fairly easily has recently been made available. Calculation of the beta-ray dose-rate distribution is based on a new set of monoenergetic electron dose point kernels which are results from an improved Monte Carlo (ETRAN) calculation. The spatial dose-rate distribution for 32P was also calculated and compared with results from the EGS4-PRESTA and ACCEPT Monte Carlo codes. The ETRAN-based distribution agrees with that from EGS4-PRESTA to within 2% out to 3.6 mm from the source, a distance over which 90% of the source energy is deposited. The ETRAN-based distribution also agrees well with that from ACCEPT between 0.6 and 4 mm from the source; at distances < 0.6 mm, values from ACCEPT are about 6% larger than ones calculated here.
authors: Department of Physics, McMaster University, Hamilton, Ontario, Canada.
authors: J
authors: J
authors: Nunes
authors: W V
authors: WV
authors: Prestwich
authors: C S
authors: CS
authors: Kwok
mesh_terms: D001610:Beta Particles; D007496:Iridium Radioisotopes; D011829:Radiation Dosage; D014867:Water
chemical_list: D007496:Iridium Radioisotopes; D014867:Water