Omeprazole induction of cytochrome P-450IA2: the importance of selecting the appropriate human model.
Watkins
P B
PB
Clinical Research Center, University of Michigan Medical School, Ann Arbor 48105.
D000818:Animals; D002478:Cells, Cultured; D019388:Cytochrome P-450 CYP1A2; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D004790:Enzyme Induction; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008954:Models, Biological; D009853:Omeprazole / Q000494:pharmacology*; D010088:Oxidoreductases / Q000096:biosynthesis*; D011817:Rabbits; D051381:Rats
D003577:Cytochrome P-450 Enzyme System; D010088:Oxidoreductases; D019388:Cytochrome P-450 CYP1A2; D009853:Omeprazole