Temperature rise in tumor tissue during high-dose-rate photoradiation.
The bioheat transfer equation and optical diffusion theory are used to develop a mathematical model for describing the thermal field in a spherical tumor and its surrounding normal tissue resulting from photoradiation. Analytical solutions to the model equations are presented for determining both the steady-state and transient temperature profiles. The effect of the optical and thermal properties of the surrounding normal tissue on the thermal field generated within the tumor is explored.
King
W E
WE
Department of Chemical Engineering, Bucknell University, Lewisburg, Pennsylvania.
Rudolph
D B
DB
D001831:Body Temperature; D006801:Humans; D006979:Hyperthermia, Induced; D008433:Mathematics; D008954:Models, Biological; D009369:Neoplasms / Q000503:physiopathology / Q000628:therapy*; D010778:Photochemotherapy