title: Carnitine acetyltransferase is absent from acuJ mutants of Aspergillus nidulans.
abstract: The acuJ mutant of Aspergillus nidulans has been shown to lack carnitine acetyltransferase (CAT) activity when grown under conditions where this activity is readily detectable in wild-type strains. Revertants selected for growth on acetate recover CAT activity and the ability to grow on long-chain fatty acids. When growing on carbon sources such as sucrose, cytosolic acetyl coenzyme A was generated by adenosine triphosphate (ATP):citrate lyase.
authors: Department of Applied Biology, University of Hull, UK.
authors: M
authors: M
authors: Midgley
mesh_terms: D001275:ATP Citrate (pro-S)-Lyase / Q000378:metabolism; D000085:Acetates / Q000378:metabolism; D019342:Acetic Acid; D001233:Aspergillus nidulans / Q000201:enzymology* / Q000235:genetics* / Q000254:growth & development; D002332:Carnitine O-Acetyltransferase / Q000235:genetics* / Q000378:metabolism; D007522:Isocitrate Lyase / Q000378:metabolism; D009154:Mutation; D013395:Sucrose / Q000378:metabolism
chemical_list: D000085:Acetates; D013395:Sucrose; D002332:Carnitine O-Acetyltransferase; D001275:ATP Citrate (pro-S)-Lyase; D007522:Isocitrate Lyase; D019342:Acetic Acid