Plants used in Guatemala for the treatment of gastrointestinal disorders. 3. Confirmation of activity against enterobacteria of 16 plants.
Ethnobotanical surveys and literature review identified 408 plants used in Guatemala for the treatment of gastrointestinal disorders. The screening of 84 showed that 34 inhibit one or more enterobacteria; 16 of these were selected for further investigation. Extracts were obtained with three solvents of different polarity (n-hexane, acetone and alcohol) and the in vitro activity was demonstrated against enteropathogenic Escherichia coli, Salmonella enteritidis and Shigella flexneri. The activity of nine ethanolic extracts against enterobacteria, particularly Acalypha guatemalensis, Diphysa robinioides, Lippia dulcis, Psidium guajava and Spondias purpurea was confirmed. The plants with antibacterial activity are discussed.
Cáceres
A
A
Faculty of Chemical Sciences and Pharmacy, University of San Carlos (USAC), Guatemala City, Guatemala.
Fletes
L
L
Aguilar
L
L
Ramirez
O
O
Figueroa
L
L
Taracena
A M
AM
Samayoa
B
B
D003967:Diarrhea / Q000188:drug therapy / Q000382:microbiology; D004755:Enterobacteriaceae / Q000187:drug effects*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D000431:Ethanol / Q000737:chemistry; D005767:Gastrointestinal Diseases / Q000188:drug therapy* / Q000382:microbiology; D006166:Guatemala; D006801:Humans; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal
D010936:Plant Extracts; D000431:Ethanol