Morphometric profiles of the mandible of SMXA recombinant inbred strains of mice and strain identification on the basis of mandible measurements.
SMXA recombinant inbred (RI) strains were derived from the F2 generation of a cross between two progenitor inbred strains, A/J and SM/J, which differ considerably with respect to many characters. In order to determine the morphometric profiles of the mandible of SMXA RI strains and to identify these strains, principal component and discriminant analyses (mandible analysis) were carried out using 11 mandible measurements. Principal component analysis revealed that the mandibles of each strain have their own characteristic size and shape. The RI strains, however, were roughly divided into 15 groups based on the morphometric profile of their mandibles. Discriminant analysis showed the probability of erroneous discrimination to be 6.49% (20/308) for the males and 8.06% (27/335) for the females. In both sexes, most of the erroneous discrimination (13 in the male, 17 in the female) occurred between RI strains having comparatively similar morphometric profiles. This suggested that all of the SMXA RI strains examined could be regarded as genetically homogeneous within each strain.
Goto
N
N
Laboratory of Animal Breeding, Faculty of Agriculture, Kobe University, Hyogo, Japan.
Yamaoka
A
A
Sudo
T
T
Mannen
H
H
Fukuta
K
K
Nishimura
M
M
D000818:Animals; D016002:Discriminant Analysis; D005260:Female; D008297:Male; D008334:Mandible / Q000033:anatomy & histology*; D051379:Mice; D008815:Mice, Inbred Strains / Q000145:classification* / Q000235:genetics; D011995:Recombination, Genetic