title: Renovascular hypertension and coronary heart disease complicating essential thrombocythemia.
abstract: A 36-year-old male was evaluated for treatment-resistant hypertension. A high platelet count 828 x 10(9).l-1, led to the diagnosis of essential thrombocythemia (ET). Aorto-renal angiography revealed critical bilateral renal artery stenosis and coronary angiography showed three-vessel disease. Percutaneous transluminal renal angioplasty was only partially successful. The patient received a 12-week course of busulphan and subsequently the thrombocyte count decreased to 200 x 10(9).l-1. Renal angiography 12 months later showed bilateral regression of the renal artery stenosis with lowering of the blood pressure to normal levels.
authors: Department of Medicine, Landspitalinn, National University Hospital, Reykjavik, Iceland.
authors: D O
authors: DO
authors: Arnar
authors: M K
authors: MK
authors: Pétursson
authors: E
authors: E
authors: Jónmundsson
authors: J
authors: J
authors: Björnsdóttir
mesh_terms: D000328:Adult; D000800:Angioplasty, Balloon; D002066:Busulfan / Q000627:therapeutic use; D003327:Coronary Disease / Q000150:complications*; D006801:Humans; D006978:Hypertension, Renovascular / Q000150:complications* / Q000628:therapy; D008297:Male; D012078:Renal Artery Obstruction / Q000150:complications; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000188:drug therapy
chemical_list: D002066:Busulfan