[Resorbable implant materials in retinal detachment surgery. Initial animal experiment studies].
In detachment surgery after a mechanically stabile chorioretinal scar is at present full scleral indentation no longer mandatory. Following these considerations absorbable scleral implants have been developed and tested in an animal model. Cylindrical pieces of absorbable composite-material with a diameter of 5 mm were sutured as radial scleral explants in 18 rabbits. The composite material consisted of a polyglactin-polydioxanon ratio 7:1. The absorption time for polyglactin is 60 days, for polydioxanon 180 days. The explants produced initially in ultrasonographically measured buckle height between 3.2 and 4.0 mm. The clinical and ultrasonographical follow up study demonstrated a continuous decrease of buckle height. Two weeks after implantation there was a medium height of 2.0 mm after five weeks a medium elevation of 0.5 mm was found. Histopathological examinations showed incidence of a slight resorptive inflammation in the area of the buckle which was not evident after 12 weeks. No scleral infiltration or scleral thinning was found. The promising results have justified controlled clinical trials with the absorbable material which might allow to combine the advantages of silicone sponge explants (precise localization) with those of scleral buckles by inflatible balloons (reversibility).
Guthoff
R
R
Universitätsaugenklinik Rostock.
Wagner
T
T
Holste
J
J
Winter
R
R
D000042:Absorption; D000818:Animals; D005549:Foreign-Body Reaction / Q000473:pathology; D008422:Materials Testing; D016687:Polydioxanone; D011098:Polyglactin 910; D019736:Prostheses and Implants; D011817:Rabbits; D012163:Retinal Detachment / Q000473:pathology / Q000601:surgery*; D012590:Sclera / Q000473:pathology; D012591:Scleral Buckling / Q000295:instrumentation*; D013537:Sutures; D014945:Wound Healing / Q000502:physiology
D016687:Polydioxanone; D011098:Polyglactin 910
Resorbierbare Plombenmaterialien in der Amotiochirurgie. Erste tierexperimentelle Untersuchungen.