[Parametric resonance as a possible mechanism of action of superlow concentrations of biologically active substances at the cellular and subcellular levels].
At extra-low concentrations of biologically active substances (BAS) the limiting stage of processes determining their action at cell and sub-sell levels is BAS diffusion to the cell surface. According to proposed parametric resonance model the BAS activity extreme values are to be observed when the reciprocal values of collision frequency between BAS molecules and cell surface coincide (by order of magnitude) with the characteristic times of conformational relaxation of certain macromolecular structures responsible of the studied process. The calculation results do not contradict the experimental data.
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D004058:Diffusion; D004798:Enzymes / Q000737:chemistry / Q000502:physiology*; D046911:Macromolecular Substances; D011487:Protein Conformation
D004798:Enzymes; D046911:Macromolecular Substances
Parmetricheskiĭ rezonans, kak vozmozhnyĭ mekhanizm deĭstviia sverkhnizkikh kontsentratsiĭ biologicheski aktivnykh veshchestv na kletochnom i subkletochnom urovniakh.