Possible mutual excitatory couplings between inspiratory neurons in caudal ventrolateral medulla of brainstem-spinal cord preparation isolated from newborn rat.
In in vitro brainstem-spinal cord preparations, projection of inspiratory neurons in the caudal ventrolateral medulla (CVL) was examined electrophysiologically, and connectivity between bilateral inspiratory neurons in the CVL was analyzed by pulse-cross correlation (PCC) analysis. CVL inspiratory neurons were found to project to the contralateral CVL and/or mainly ipsilateral spinal cord. PCC analysis revealed significant peaks with different latency on both sides of time zero in 3 of 8 pairs. Results were consistent with mono- or oligo-synaptic excitatory connections between bilateral inspiratory neurons in the CVL.
Onimaru
H
H
Department of Physiology, Showa University School of Medicine, Tokyo, Japan.
Kashiwagi
M
M
Arata
A
A
Homma
I
I
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D001933:Brain Stem / Q000502:physiology*; D002217:Carbachol / Q000494:pharmacology; D004594:Electrophysiology; D008526:Medulla Oblongata / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D012119:Respiration / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*
D002217:Carbachol; D000109:Acetylcholine