[Effect of aminophylline on respiratory function in patients with chronic renal failure treated by peritoneal dialysis].
In 8 patients with chronic renal failure aminophylline influence was studied on respiratory function. No changes were seen in lung volumes after 30 minutes of intravenous aminophylline infusion. After 2 weeks of intraperitoneal infusion of aminophylline, maximal ventilation, vital capacity, forced vital capacity and inspiratory residual volume rose significantly. Residual volume and the ratio residual volume/total lung capacity, decreased. This changes may indicate an improved contractility of the respiratory muscles. A rise in the concentration of oxypurines after peritoneal dialysis and a significant improvement in the arterial oxygen tension indicate that aminophylline influences the respiratory function by bronchodilatation and by contractility improvement of the respiratory muscles.
Wanic-Kossowska
M
M
Kliniki Nefrologii Instytutu Chorób Wewnetrznych Akademii Medycznej im. K. Marcinkowskiego, Poznaniu.
Chmara
E
E
Banaszak
F
F
D000628:Aminophylline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D012119:Respiration / Q000187:drug effects*; D012129:Respiratory Function Tests
D000628:Aminophylline
Wpływ aminofiliny na funkcje układu oddechowego u chorych z przewlekła niewydolnościa nerek leczonych dializa otrzewnowa.