title: Alkaloids from bufonid toads (Melanophryniscus): decahydroquinolines, pumiliotoxins and homopumiliotoxins, indolizidines, pyrrolizidines, and quinolizidines.
abstract: Skins of bufonid toads of the genus Melanophryniscus contain several classes of alkaloids: decahydroquinolines, pumiliotoxins, allopumiliotoxins, homopumiliotoxins, both 3,5- and 5,8-disubstituted indolizidines, 3,5-disubstituted pyrrolizidines, and a 1,4-disubstituted quinolizidine. Tricyclic alkaloids, including precoccinelline [193A] and alkaloid 236, an oxime methyl ether, are present in one population of Melanophryniscus stelzneri.
authors: Laboratory of Bioorganic Chemistry, NIDDK, NIH, Bethesda, MD 20892.
authors: H M
authors: HM
authors: Garraffo
authors: T F
authors: TF
authors: Spande
authors: J W
authors: JW
authors: Daly
authors: A
authors: A
authors: Baldessari
authors: E G
authors: EG
authors: Gros
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D002025:Bufonidae / Q000378:metabolism*; D008401:Gas Chromatography-Mass Spectrometry; D013058:Mass Spectrometry; D008968:Molecular Conformation; D012867:Skin / Q000737:chemistry; D013055:Spectrophotometry, Infrared
chemical_list: D000470:Alkaloids