title: Studies on T. spiralis and T pseudospiralis larvae recovered from mice immunized with heterologous Trichinella antigen.
abstract: In this study, S3 antigen of T. spiralis and T. pseudospiralis was given to the heterologous infection in albino mice. The recovered larvae were studied as regards: their number, length and steroscan examination. It was found that vaccination of mice with T. spiralis (S3) antigen induced reduction in T. pseudospiralis larval count by 66.43% and significant reduction in length. Using T. pseudospiralis (S3) antigen reduction of 74.77% in T. spiralis larval count was detected as well as significant reduction in length. Scanning electron microscopic (SEM) examination revealed more or less similar finding in both species: loss of integrity of the cuticle, some of the larvae were attacked by granulocytes mainly eosinophils and few larvae appeared completely destructed with loss of normal architecture. A peculiar finding was noticed in case of T. pseudospiralis larvae in form of fine electron dense deposits giving the cuticular surface a motling appearance.
authors: Department of Parasitology, Faculty of Medicine, Alexandria University, Egypt.
authors: L M
authors: LM
authors: Boulos
authors: L M
authors: LM
authors: Abou Samra
authors: I H
authors: IH
authors: Hegazy
mesh_terms: D000818:Animals; D000947:Antigens, Helminth / Q000276:immunology*; D007814:Larva / Q000276:immunology / Q000648:ultrastructure; D051379:Mice; D008855:Microscopy, Electron, Scanning; D014234:Trichinella / Q000276:immunology / Q000648:ultrastructure*; D017160:Trichinella spiralis / Q000276:immunology / Q000648:ultrastructure*; D014235:Trichinellosis / Q000469:parasitology* / Q000517:prevention & control; D014611:Vaccination
chemical_list: D000947:Antigens, Helminth