Metastatic prostate cancer simulating sclerosing cholangitis.
We report what we believe to be the first case of metastatic prostate cancer presenting as sclerosing cholangitis. In a 71-year-old man with known prostate cancer and cholestatic jaundice, an endoscopic retrograde cholangiopancreatography revealed multifocal strictures of both the intrahepatic and extrahepatic biliary system consistent with sclerosing cholangitis. Review of a liver biopsy and cholecystectomy specimen showed metastases from prostate cancer, which stained positively with prostate-specific antigen. Multiple hepatic metastases from prostate cancer should be included among the conditions that simulate primary sclerosing cholangitis on cholangiography.
Taylor
J
J
Division of Gastroenterology, Mayo Clinic, Rochester, MN 55905.
Lindor
K
K
D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015209:Cholangitis, Sclerosing / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005706:Gallbladder Neoplasms / Q000175:diagnosis / Q000556:secondary*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*