title: Cytotoxicity of some modified root canal sealers and their leachable components.
abstract: The toxic effects of modified endodontic sealers, Fillcanal, N-Rickert, FS, and Sealer 26, were assessed. The material toxicity was measured through radiochromium release method that uses direct and indirect contact methods. The sealers were evaluated freshly mixed and after various setting times. L929 mouse and periodontal ligament fibroblast cells were used as target cells. Fillcanal, N-Rickert, and FS showed high toxicity. Fillcanal leaches toxic material when fresh and after setting time. Sealer 26 was the least toxic.
authors: University of Connecticut Health Center, Farmington.
authors: S V
authors: SV
authors: Barbosa
authors: K
authors: K
authors: Araki
authors: L S
authors: LS
authors: Spångberg
mesh_terms: D000818:Animals; D001466:Barium Sulfate / Q000633:toxicity; D001729:Bismuth / Q000633:toxicity; D001881:Borates / Q000633:toxicity; D002126:Calcium Hydroxide / Q000633:toxicity; D002860:Chromium Radioisotopes; D004338:Drug Combinations; D004853:Epoxy Resins; D005054:Eugenol / Q000633:toxicity; D007739:L Cells; D008422:Materials Testing; D008709:Methenamine / Q000633:toxicity; D051379:Mice; D012117:Resins, Synthetic / Q000633:toxicity; D012387:Root Canal Filling Materials / Q000633:toxicity*; D012834:Silver / Q000633:toxicity; D014025:Titanium / Q000633:toxicity; D015034:Zinc Oxide / Q000633:toxicity; D015035:Zinc Oxide-Eugenol Cement / Q000633:toxicity*
chemical_list: D001881:Borates; D002860:Chromium Radioisotopes; D004338:Drug Combinations; D004853:Epoxy Resins; C080619:FS Paste; C080618:N-Rickert sealer; D012117:Resins, Synthetic; D012387:Root Canal Filling Materials; C080620:Sealer 26; D015035:Zinc Oxide-Eugenol Cement; D001466:Barium Sulfate; D012834:Silver; D005054:Eugenol; C028044:epoxy resin AH-26; C038425:Fillcanal; D014025:Titanium; D008709:Methenamine; D002126:Calcium Hydroxide; D015034:Zinc Oxide; D001729:Bismuth