Looking into the grooves of DNA.
The present study is aimed at understanding the effects of DNA sequence, local conformation, and curvature on groove geometry. Energy-optimized structures are obtained by Jumna methodology; groove geometry is analyzed by a recently developed technique that allows an accurate and continuous measurement of width and depth. The mechanics of groove deformations is also studied and analyzed in terms of helicoidal parameters.
Boutonnet
N
N
Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique, Paris, France.
Hui
X
X
Zakrzewska
K
K
D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D013816:Thermodynamics
D009838:Oligodeoxyribonucleotides; D004247:DNA