Increased resistance to quinolone in Catalonia, Spain.
From 1989 to 1991, the level of resistance to ciprofloxacin in our hospital increased from 0.47% to 6.7% in opportunistic Enterobacteriaceae, from 9.9% to 16% in Pseudomonas aeruginosa and from 8.27% to 31.8% in Campylobacter jejuni-coli. We also observed an increase in quinolone consumption from 1.1 in 1989 to 1.5 defined daily doses per 1000 inhabitants per day in 1991.
Mirelis
B
B
Microbiology Service, Hospital De Sant Pau, Barcelona, Spain.
Miro
E
E
Navarro
F
F
Ogalla
C A
CA
Bonal
J
J
Prats
G
G
D000890:Anti-Infective Agents / Q000494:pharmacology*; D002169:Campylobacter Infections / Q000188:drug therapy; D002939:Ciprofloxacin / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D009894:Opportunistic Infections / Q000188:drug therapy; D011552:Pseudomonas Infections / Q000188:drug therapy; D013030:Spain; D013997:Time Factors
D000890:Anti-Infective Agents; D002939:Ciprofloxacin