Terpestacin, a new syncytium formation inhibitor from Arthrinium sp.
Terpestacin, a new antibiotic which inhibits syncytium formation, was isolated from Arthrinium sp. FA1744 (ATCC 74132). The structure of terpestacin was elucidated as a bicyclic sesterterpene on the basis of spectroscopic data and chemical derivatization.
Oka
M
M
Bristol-Myers Squibb Research Institute, Tokyo, Japan.
Iimura
S
S
Tenmyo
O
O
Sawada
Y
Y
Sugawara
M
M
Ohkusa
N
N
Yamamoto
H
H
Kawano
K
K
Hu
S L
SL
Fukagawa
Y
Y
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001643:Bridged Bicyclo Compounds / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002460:Cell Line; D005285:Fermentation; D015726:Giant Cells / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D001643:Bridged Bicyclo Compounds; C080890:terpestacin