Clinical study of bendazac lysine for in vivo contact lens cleaning.
Bendazac Lysine (BZL), a nonsteroidal anti-inflammatory drug (NSAID), prevents denaturation of proteins secondary to chemical and physical activity. The major protein deposited on soft contact lenses is lysozyme, derived from the preocular tear film. We evaluated the effectiveness of eye drops formulated with BZL for in vivo prevention of proteinaceous deposits on contact lenses and found them to be useful in inhibiting protein deposition during a 6-month clinical trial.
Evans
T C
TC
Ophthalmology Department, California Pacific Medical Centre, San Francisco.
Levy
B
B
Szabocsik
J
J
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000009:adverse effects; D003261:Contact Lenses; D004203:Disinfection / Q000379:methods; D005136:Eye Proteins / Q000378:metabolism; D005260:Female; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D007191:Indazoles / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D009883:Ophthalmic Solutions; D010919:Placebos; D011092:Polyethylene Glycols
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005136:Eye Proteins; D007191:Indazoles; D009883:Ophthalmic Solutions; D010919:Placebos; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols; C036067:bendazac lysine