Effects of Chlorella stigmatophora extract on the central nervous system.
At the level of the central nervous system an aqueous extract of the marine microalga Chlorella stigmatophora (Butcher) (Chlorophyceae) showed anti-dopaminergic-type activity in assays of its effects on spontaneous motor response, rectal temperature, motor coordination, amphetamine-induced hypermotility, exploratory conduct, muscle relaxation, catalepsy, conditioned avoidance responses, oxotremorine-induced cholinergic syndrome, and pentylenetetrazole-induced convulsions.
Laguna
M R
MR
Departamento de Farmacología, Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Santiago de Compostela, Spain.
Villar
R
R
Calleja
J M
JM
Cadavid
I
I
D000818:Animals; D002490:Central Nervous System / Q000187:drug effects*; D002708:Chlorella / Q000737:chemistry*; D005260:Female; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*
D010936:Plant Extracts