Lack of tumorigenic activity of 1,1-dimethylhydrazine in Syrian golden hamsters treated by subcutaneous injection.
Syrian golden hamsters were treated throughout their lifespan by weekly subcutaneous injections of 1,1-dimethylhydrazine (1,1-DMH) at doses of 0, 8, 17 and 35 mg/kg body weight. In contrast to our previous study using European hamsters, no treatment-related tumors occurred in this study.
Jeong
J Y
JY
Institute of Experimental Pathology, Hannover Medical School, Germany.
Kamino
K
K
D000818:Animals; D015197:Carcinogenicity Tests; D002273:Carcinogens / Q000008:administration & dosage*; D006224:Cricetinae; D004127:Dimethylhydrazines / Q000008:administration & dosage*; D005260:Female; D007279:Injections, Subcutaneous; D008297:Male; D008647:Mesocricetus
D002273:Carcinogens; D004127:Dimethylhydrazines; C013958:dimazine