title: Sodium lactate infusion in late luteal phase dysphoric disorder.
abstract: The effects of sodium lactate infusion were compared in 13 women who sought treatment for marked premenstrual dysphoric changes that met criteria for late luteal phase dysphoric disorder and 7 control women. No subject had a lifetime history of panic disorder. The rate of blindly rated panic to sodium lactate was 7 (58%) in patients and 0% in controls. Nonpanicking patients also had higher Modified Acute Panic Inventory scores than control subjects. The differences cannot be fully explained on the basis of a history of panic attacks. Further study is warranted.
authors: Department of Psychiatry, College of Physicians and Surgeons, Columbia University.
authors: D
authors: D
authors: Sandberg
authors: J
authors: J
authors: Endicott
authors: W
authors: W
authors: Harrison
authors: J
authors: J
authors: Nee
authors: J
authors: J
authors: Gorman
mesh_terms: D000328:Adult; D001143:Arousal / Q000187:drug effects / Q000502:physiology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007773:Lactates; D019344:Lactic Acid; D008183:Luteal Phase / Q000187:drug effects* / Q000502:physiology; D016584:Panic Disorder / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D010555:Personality Inventory; D011293:Premenstrual Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D011603:Psychophysiology; D016037:Single-Blind Method
chemical_list: D007773:Lactates; D019344:Lactic Acid