title: Studies on varicocele. II. The inhibin secretion.
abstract: In this paper a previous interpretation given by the authors concerning one of the ways varicocele can affect fertility is confirmed. Moreover, it is definitely demonstrated that the high temperature stimulates inhibin secretion (and probably the testosterone-estradiol conversion) in the Sertoli cells, while the somatomedin secretion in vitro seems to be unaffected. It means that the action of the temperature on the germinal cells seems to be mediated by the pathway: inhibin (plus estradiol)-->pituitary-->FSH. Inhibin in the Golgi complex of Sertoli and germinal cells has been detected by electron microscopical immunocytochemical techniques.
authors: Institute of General Biology of the University, Siena, Italy.
authors: B
authors: B
authors: Baccetti
authors: A G
authors: AG
authors: Burrini
authors: S
authors: S
authors: Capitani
authors: E
authors: E
authors: Costantino-Ceccarini
authors: G
authors: G
authors: Collodel
authors: G
authors: G
authors: Di Cairano
authors: M
authors: M
authors: Estenoz
authors: L
authors: L
authors: Martini
authors: E
authors: E
authors: Moretti
authors: P
authors: P
authors: Piomboni
mesh_terms: D000328:Adult; D000818:Animals; D002478:Cells, Cultured; D005246:Feedback; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007265:Inhibins / Q000097:blood / Q000378:metabolism*; D008297:Male; D008954:Models, Biological; D051381:Rats; D017208:Rats, Wistar; D012708:Sertoli Cells / Q000378:metabolism*; D013002:Somatomedins / Q000378:metabolism; D013091:Spermatogenesis; D013094:Spermatozoa / Q000648:ultrastructure; D013739:Testosterone / Q000097:blood; D014646:Varicocele / Q000097:blood / Q000473:pathology*
chemical_list: D013002:Somatomedins; D013739:Testosterone; D007265:Inhibins; D005640:Follicle Stimulating Hormone