Acceleration of the ventricular response in paroxysmal lone atrial fibrillation following the injection of adenosine.
Treatment of a patient with new onset atrial fibrillation with intravenous adenosine was followed by transient but significant acceleration of the ventricular rate. This unexpected response to adenosine can be explained by a predominating increase in sympathetic discharge relative to the drug's direct atrial ventricular nodal-blocking action.
White
R D
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Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905.
D000241:Adenosine / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D001281:Atrial Fibrillation / Q000188:drug therapy*; D004562:Electrocardiography / Q000187:drug effects*; D006801:Humans; D008297:Male; D013617:Tachycardia, Supraventricular / Q000188:drug therapy / Q000503:physiopathology*
D000241:Adenosine