title: Incidence of nervous system Borrelia burgdorferi infection in patients with lumboradicular syndrome.
abstract: We investigated 103 consecutive patients primarily admitted to our Department of Neurosurgery (36 women, age: median 44, range 21-79; 67 men, age: 47, range 19-77) suffering from low back pain radiating into one or both legs. Neurological examination combined with computer tomography and lumbar myelography revealed lumbar-disc herniation in 74, vertebrostenosis in 10 and relapsed disc herniation in 9 patients. In 9 patients the diagnosis of pseudoradicular syndrome was established without definite neuroradiological morphological evidence. Two patients were diagnosed as having polyneuropathy, and 1 patient suffered from a nervus ischiadicus lesion due to a gluteal abscess. CSF of all patients was examined according to a fixed routine schedule (cells, protein, sugar, immunoglobulins, IgG index). Antibodies to Borrelia burgdorferi were found in the serum and CSF of 5.8%, and in the serum alone of 2% of patients. Intrathecally produced specific antibodies were detected in 3 patients (2.9%) with neuroradiological evidence of disc or spinal-canal disease, indicating the coexistence of previous CNS infection by B. burgdorferi with lumbar-disc herniation. None of the patients showed CSF pleocytosis; thus, in no case was acute radiculitis due to B. burgdorferi infection diagnosed.
authors: Department of Neurology, University Hospital Innsbruck, Austria.
authors: E
authors: E
authors: Schmutzhard
authors: I
authors: I
authors: Mohsenipour
authors: G
authors: G
authors: Stanek
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015994:Incidence; D007405:Intervertebral Disc Displacement / Q000175:diagnosis*; D008161:Lumbosacral Region; D008193:Lyme Disease / Q000150:complications / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000150:complications / Q000453:epidemiology*; D011446:Prospective Studies; D011843:Radiculopathy / Q000175:diagnosis*; D013577:Syndrome