title: [Beta-carbolines (harman/norharman) are increased in heroin dependent patients].
abstract: Endogenous substances resulting from interactions between alcohol and possibly opioid metabolites and neurotransmitters (dopamine, indolamines) are mediators of the pathochemical process towards dependence. Beta-carbolines are increased in alcoholics and--according to our own results--in heroin-addicts. Still unclear is the impact of other psychopathological disturbances like states of anxiety or depression; unclear is also, if it has to be interpreted as state, trait or residual marker of the dependence syndrome.
authors: Psychiatrische Universitätsklinik, Basel.
authors: R
authors: R
authors: Stohler
authors: H
authors: H
authors: Rommelspacher
authors: D
authors: D
authors: Ladewig
authors: G
authors: G
authors: Dammann
mesh_terms: D000328:Adult; D002243:Carbolines; D005260:Female; D006247:Harmine / Q000031:analogs & derivatives* / Q000097:blood; D006556:Heroin Dependence / Q000097:blood* / Q000534:rehabilitation; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use; D013375:Substance Withdrawal Syndrome / Q000097:blood
chemical_list: D002243:Carbolines; D006247:Harmine; C005010:harman; C010262:norharman; D008691:Methadone
vernacular_title: Beta-Carboline (Harman/Norharman) sind bei Heroinabhängigen erhöht.