Cutaneous phaeohyphomycosis due to Alternaria alternata responding to itraconazole.
An 81-year-old man presented with a spreading, eczematous-appearing rash on the dorsum of the right hand and forearm, originating from three small, probably post-traumatic, ulcers over the knuckles. He had the nephrotic syndrome for which he was on 60 mg prednisone daily. Histology of a biopsy of lesional skin was consistent with phaeohyphomycosis and Alternaria alternata was cultured. The rash cleared following treatment with 100 mg itraconazole daily and tapering of his prednisone dose.
Duffill
M B
MB
Department of Dermatology, Waikato Hospital, Hamilton, New Zealand.
Coley
K E
KE
D000368:Aged; D000369:Aged, 80 and over; D000528:Alternaria; D003881:Dermatomycoses / Q000382:microbiology*; D006229:Hand Dermatoses / Q000382:microbiology*; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy; D009894:Opportunistic Infections / Q000382:microbiology*; D011241:Prednisone / Q000627:therapeutic use
D011241:Prednisone