Analysis of hepatic recurrence of colorectal cancer after resection of hepatic metastases.
Forty patients with history of resected hepatic metastases of colorectal cancer were examined for pattern of recurrence. The 5-year survival rate was 41.3% for 40 patients. Recurrences of the malignancy were seen in 25 of the patients, with hepatic recurrence in 42.5% of them. The hepatic recurrence rate did not correlate with the lobar distribution of metastases or surgical methods. The pathological margins of less than 1 cm, 3 or more liver metastatic lesions, and the metastatic lesions of greater than 5 cm were at increased risk of hepatic recurrence. The recurrence rate was high, or 56% for aneuploid tumors, while it was 18.5% for diploid tumors.
Yamaguchi
A
A
Department of Surgery II, School of Medicine, Kanazawa University, Japan.
Kurosaka
Y
Y
Kanno
M
M
Yonemura
Y
Y
Izumi
R
R
Miwa
K
K
Miyazaki
I
I
D000782:Aneuploidy; D015179:Colorectal Neoplasms / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D004171:Diploidy; D005260:Female; D005434:Flow Cytometry; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology / Q000556:secondary* / Q000601:surgery*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D012307:Risk Factors; D015996:Survival Rate
D004273:DNA, Neoplasm