title: Radical hysterectomy for stage IB adenocarcinoma of the cervix: the University of Miami experience.
abstract: The treatment of adenocarcinoma of the cervix has traditionally followed that of squamous cancer. A 25-year review of 88 radical hysterectomies for Stage IB adenocarcinoma of the cervix at the University of Miami/Jackson Medical Center (UM) is compared to over 1600 cases reported in the literature. Adenocarcinoma represented 10.4% of 978 radical hysterectomies performed at UM from July 1965 to December 1990. In a survey of the literature, patients with Stage IB cervical adenocarcinoma treated by radical surgery alone had a statistically better 5-year survival than those treated by radiation alone (79% vs 67%, respectively; P < or = 0.05). Furthermore, no additional benefit was achieved by combining the two therapeutic modalities. The corrected 5-year survival at UM is 81% for Stage IB adenocarcinoma of the cervix treated with radical hysterectomy, a number consistent with the cumulative data base. Radical surgery is an acceptable primary therapy in Stage IB adenocarcinoma of the cervix.
authors: Department of Obstetrics & Gynecology, University of Miami School of Medicine, Florida 33101.
authors: A
authors: A
authors: Steren
authors: H N
authors: HN
authors: Nguyen
authors: H E
authors: HE
authors: Averette
authors: R
authors: R
authors: Estape
authors: R
authors: R
authors: Angioli
authors: D M
authors: DM
authors: Donato
authors: M A
authors: MA
authors: Penalver
authors: B U
authors: BU
authors: Sevin
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D015993:Life Tables; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local; D011859:Radiography; D012189:Retrospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*