title: Rheological evaluation of X-ray irradiated blood.
abstract: CPD blood, in glass containers and polyvinyl chloride (PVC) bags, was X-irradiated with 50 Gy (n = 4), and then stored for up to 4 weeks. Rheological, hematological and biochemical changes of the red cells during storage were examined. Changes in blood viscosity and various properties of red cells (deformability, shape, hematological indices and concentrations of 2,3-diphosphoglycerate and nucleotides) during storage at 4 degrees C were not altered by the irradiation. The rheological, biochemical and morphological properties of red cells were as well preserved in PVC bags as in glass containers. No abnormal and/or cross-linked proteins in red-cell membranes were induced by the irradiation. Irradiation of PVC bags did not affect the above properties of red cells through any changes in the bag constituents. In conclusion, X-ray irradiation with 50 Gy to CPD blood in PVC bags does not affect the rheological functions of red cells.
authors: Department of Physiology, School of Medicine, Ehime University, Shigenobu, Japan.
authors: Y
authors: Y
authors: Suzuki
authors: A
authors: A
authors: Seiyama
authors: N
authors: N
authors: Tateishi
authors: S
authors: S
authors: Yamanishi
authors: N
authors: N
authors: Maeda
mesh_terms: D001769:Blood / Q000528:radiation effects*; D001793:Blood Preservation / Q000379:methods*; D001809:Blood Viscosity / Q000528:radiation effects; D048429:Cell Size / Q000528:radiation effects; D004907:Erythrocyte Deformability / Q000528:radiation effects; D004912:Erythrocytes / Q000528:radiation effects*; D005898:Glass; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000528:radiation effects; D009943:Organophosphorus Compounds / Q000097:blood; D011143:Polyvinyl Chloride; D012212:Rheology; D012996:Solutions
chemical_list: D008565:Membrane Proteins; D009943:Organophosphorus Compounds; D012996:Solutions; D011143:Polyvinyl Chloride