TiN coating: surface characterization and haemocompatibility.
The left ventricular assist device under consideration is based on the principle of the Maillard-Wankel rotary pump. The construction materials must meet stringent requirements. Titanium nitride was chosen for its surface properties and graphite for its bulk characteristics. The purpose of this study was to characterize the chemical vapour deposition titanium nitride coating via morphology, roughness, crystallinity, chemical composition, to report and discuss the results of in vitro haemocompatibility tests (protein adsorption, platelet retention, haemolysis) and to discuss physico-chemical and biological results. This chemical vapour deposition titanium nitride coating is well tolerated by the blood despite its surface irregularities, and appears as a good candidate material after improvements.
Dion
I
I
INSERM U.306, Université de Bordeaux II, France.
Rouais
F
F
Trut
L
L
Baquey
C
C
Monties
J R
JR
Havlik
P
P
D000042:Absorption; D001672:Biocompatible Materials; D001792:Blood Platelets; D004912:Erythrocytes; D006108:Graphite; D006353:Heart-Assist Devices; D006461:Hemolysis; D006801:Humans; D066298:In Vitro Techniques; D008855:Microscopy, Electron, Scanning; D014025:Titanium; D014961:X-Ray Diffraction
D001672:Biocompatible Materials; C041500:titanium nitride; D006108:Graphite; D014025:Titanium