[Corneal crystalline deposits in benign monoclonal gammopathies. Apropos of 3 cases].
Unusual corneal crystalline opacities at the level of Bowman's membrane and superficial stroma were observed in 3 patients with benign monoclonal gammopathy. Corneal immunohistochemical examination showed that the deposits consisted of immunoglobulin crystals identical to the paraprotein found in the serum (with the same light chain: Kappa in 2 cases and Lambda in the third case). The factors and mechanisms governing intracorneal immunoglobulin deposition in the cornea are discussed.
Binaghi
M
M
Service d'anatomo-pathologie, Hôpital Henri-Mondor, Créteil.
Teboul
J C
JC
Gaulard
P
P
Divine
M
M
Coscas
G
G
D000328:Adult; D000368:Aged; D003315:Cornea / Q000473:pathology* / Q000648:ultrastructure; D003318:Corneal Opacity / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000473:pathology*
Dépôts cornéens cristallins dans les gammapathies monoclonales "bénignes". A propos de 3 observations.