title: Adult T cell leukaemia lymphoma in a non-aboriginal Australian woman with no apparent risk factors.
abstract: OBJECTIVE
  To present a case of adult T cell leukaemia lymphoma (ATLL) in a non-Aboriginal Australian woman with no apparent risk factor.
  
  
  METHODS
  A 43-year-old Australian woman of European descent presented with a febrile illness associated with generalised lymphadenopathy and splenomegaly.
  
  
  METHODS
  There was lymphocytosis in the peripheral blood with a T helper cell phenotype. There were also lytic bone lesions with associated hypercalcaemia. HTLV-1 antibody was detected by agglutination assay and confirmed by western blot test.
  
  
  RESULTS
  After initial response to CHOP chemotherapy (cyclophosphamide, doxorubicin, vincristine, prednisolone), she relapsed and died with central nervous system involvement eight months after the initial diagnosis.
  
  
  CONCLUSIONS
  To our knowledge this is only the third case of ATLL in a non-Aboriginal person in Australia.
authors: Department of Haematology and Medical Oncology, Peter MacCallum Cancer Institute, Melbourne, Vic.
authors: M K
authors: MK
authors: Tong
authors: M
authors: M
authors: Wolf
authors: S
authors: S
authors: Juneja
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001315:Australia; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis / Q000473:pathology; D011241:Prednisone / Q000008:administration & dosage; D012307:Risk Factors; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone