title: Change of paraprotein from IgG lambda to lambda chain in myeloma.
abstract: We describe a unique case of IgG lambda myeloma in which a plasma cell leukemia developed and the paraprotein changed from IgG lambda to lambda chain, the latter inducing fatal renal failure. In addition, J-chain was detected in the cytoplasm of the plasma cell leukemia cells.
authors: Third Department of Internal Medicine, Gunma University School of Medicine, Japan.
authors: M
authors: M
authors: Sawamura
authors: K
authors: K
authors: Murayama
authors: S
authors: S
authors: Tokizawa
authors: T
authors: T
authors: Matsushima
authors: J
authors: J
authors: Tamura
authors: H
authors: H
authors: Murakami
authors: T
authors: T
authors: Naruse
authors: J
authors: J
authors: Tsuchiya
mesh_terms: D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism*; D007144:Immunoglobulin J-Chains / Q000378:metabolism*; D007146:Immunoglobulin lambda-Chains / Q000097:blood / Q000378:metabolism*; D007952:Leukemia, Plasma Cell / Q000097:blood / Q000378:metabolism*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood / Q000378:metabolism*
chemical_list: D007074:Immunoglobulin G; D007144:Immunoglobulin J-Chains; D007146:Immunoglobulin lambda-Chains