Comparison of the acceptability of the Ventolin metered-dose inhaler and the Bricanyl Turbuhaler.
One hundred fifty-nine asthmatic patients aged 19 to 76 years completed an open crossover-designed study comparing the acceptability of the Bricanyl Turbuhaler (BTH) and the Ventolin metered-dose inhaler (VMDI). The doses given were presumed to be equiactive. Each treatment period lasted for 14 days. Patients registered morning and evening peak expiratory flow rate (PEFR) before and five minutes after medication. Asthma symptoms as well as adverse events were registered on diary cards. After each study period a questionnaire containing acceptability questions was completed. At the end of the study the patients indicated their preference for one of the two treatments. The two treatments were equal concerning bronchodilation and asthma symptoms. There was an overall preference for the Bricanyl Turbuhaler.
Vilsvik
J S
JS
Department of Pulmonary Diseases, Regional Hospital, University of Trondheim, Norway.
Ringdal
N
N
Albrektsen
T
T
Holthe
S
S
D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D000420:Albuterol / Q000008:administration & dosage / Q000009:adverse effects; D002940:Circadian Rhythm; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers / Q000592:standards*; D010147:Pain Measurement; D010342:Patient Acceptance of Health Care; D010366:Peak Expiratory Flow Rate; D013726:Terbutaline / Q000008:administration & dosage / Q000009:adverse effects
D013726:Terbutaline; D000420:Albuterol