A study of gastric emptying in non-ulcer dyspepsia using a new ultrasonographic method.
To ascertain the effect of gastric emptying on the symptoms of non-ulcer dyspepsia (NUD) patients, we randomly selected 60 NUD patients and, as control, 26 dyspepsia-free volunteers. We measured the gastric emptying time of mixed food (270 kcal), using real-time ultrasonography in two ways. NUD patients were divided randomly into two groups and given domperidone or placebo in a double-blind trial. Of the NUD patients 48% had delayed gastric emptying times and associated epigastric pain, bloating, early satiety, and regurgitation. A prokinetic agent not only improved emptying time but also relieved some of the symptoms of the NUD patients. Real-time ultrasonography proved a useful method for evaluating gastric emptying.
Duan
L P
LP
Digestive Diseases Research Center, Beijing Medical University, People's Republic of China.
Zheng
Z T
ZT
Li
Y N
YN
D000328:Adult; D004415:Dyspepsia / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D005260:Female; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013270:Stomach / Q000000981:diagnostic imaging; D014463:Ultrasonography