title: Correlation of ultrasound and renal scintigraphy in children with unilateral hydronephrosis in primary workup.
abstract: Ultrasound accurately detects hydronephrosis in infants and children, while nuclear medicine techniques quantify relative renal function in addition to characterizing the urodynamic relevance of hydronephrosis. This prospective study was undertaken to examine the relationship between ultrasound morphological findings and relative renal function, quantified with dynamic 99mtechnetium mercaptotriacetylglycine imaging, in the initial diagnostic workup of children with unilateral hydronephrosis. The ultrasound grade of hydronephrosis and relative renal function ipsilateral to the hydronephrosis were inversely related, indicating that with more severe hydronephrosis ultrasound fails to estimate the potential reduction of relative kidney function. Because renal function is not necessarily affected by hydronephrosis, renal scintigraphy is indicated to assess the functional status of hydronephrotic kidneys.
authors: Division of Nuclear Medicine and Special Biophysics, UCLA School of Medicine 90024-1721.
authors: E U
authors: EU
authors: Nitzsche
authors: L B
authors: LB
authors: Zimmerhackl
authors: R A
authors: RA
authors: Hawkins
authors: B
authors: B
authors: Stöver
authors: A
authors: A
authors: Frankenschmidt
authors: G
authors: G
authors: Sigmund
authors: Y
authors: Y
authors: Choi
authors: C K
authors: CK
authors: Hoh
authors: E A
authors: EA
authors: Moser
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007223:Infant; D007677:Kidney Function Tests; D008297:Male; D011446:Prospective Studies; D011877:Radionuclide Imaging; D017263:Technetium Tc 99m Mertiatide; D014463:Ultrasonography
chemical_list: D017263:Technetium Tc 99m Mertiatide