Reimplantation of ventral rootlets into the cervical spinal cord after their avulsion: an anterior surgical approach.
Root avulsions from the cervical spinal cord due to traction injuries are beyond repair up to the present day. An anterior surgical approach has been developed in cats for reimplantation of the ventral rootlets into the site of avulsion. The consecutive surgical steps towards exposure of the ventral surface of the cervical cord are given in detail. The morphological relations during the operative procedure are explained in the text and by illustrations. In this study the surgery related mortality rate was 16% and the overall mortality rate amounted to 21%. Loss of blood, initially a major problem, was coped with by increasing technical experience and the infusion of plasma expanding fluid. In 2 animals with survival times of 209 and 293 days respectively, many ventral horn motoneurons were found HRP-positive after retrograde HRP transport through the site of reimplantation. The findings provide evidence that the axonal continuity between reimplanted ventral roots and their motoneurons may be restored.
Hoffmann
C F
CF
Department of Neurosurgery, University of Leiden, The Netherlands.
Thomeer
R T
RT
Marani
E
E
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D001917:Brachial Plexus / Q000293:injuries* / Q000473:pathology / Q000601:surgery; D002415:Cats; D008297:Male; D008866:Microsurgery; D009046:Motor Neurons / Q000473:pathology; D009416:Nerve Regeneration / Q000502:physiology*; D012421:Rupture; D013116:Spinal Cord / Q000473:pathology / Q000601:surgery; D013119:Spinal Cord Injuries / Q000473:pathology / Q000601:surgery*; D013126:Spinal Nerve Roots / Q000293:injuries* / Q000473:pathology / Q000601:surgery