Colon transplantation: a new microvascular technique.
This paper describes a new transplantation technique, using the colon instead of the small bowel for intestinal transplantation. With microsurgical techniques, allogeneic colon transplantation was carried out in rats in a heterotopic fashion. The vascular pedicle containing the aortic cuff and the portal vein was anastomosed to the aorta and the inferior vena cava of the host, respectively. The technique has proven reliable and reproducible, and our preliminary results suggest that the colon produces a milder rejection response than transplantation of the small bowel.
Plapler
H
H
Department of Surgery, University of Toronto, Ontario, Canada.
Cohen
Z
Z
D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001011:Aorta / Q000601:surgery; D003106:Colon / Q000098:blood supply / Q000637:transplantation*; D003125:Colostomy; D006084:Graft Rejection / Q000473:pathology; D007421:Intestine, Small / Q000637:transplantation; D008197:Lymph Node Excision; D008638:Mesenteric Arteries / Q000601:surgery; D008866:Microsurgery / Q000379:methods*; D011169:Portal Vein / Q000601:surgery; D051381:Rats; D011917:Rats, Inbred Lew; D011920:Rats, Inbred WF; D015996:Survival Rate; D014656:Vascular Surgical Procedures / Q000379:methods*; D014682:Vena Cava, Inferior / Q000601:surgery