title: Cardiac surgery with extracorporeal circulation in severe factor VII deficiency.
abstract: We describe here successful open heart surgery with extracorporeal circulation and haemodilution in a child with severe congenital factor VII deficiency. Substitution therapy was realized with factor VII concentrate (SD proconvertin concentrate, Bio-Transfusion). This is the first report case of successful cardiac surgery in severe congenital factor VII deficiency.
authors: Department of Haematology, Hôpital Universitaire des Enfants Reine Fabiola, Free University Brussels (ULB), Belgium.
authors: A
authors: A
authors: Ferster
authors: V
authors: V
authors: Capouet
authors: A
authors: A
authors: Deville
authors: P
authors: P
authors: Fondu
authors: F
authors: F
authors: Corazza
mesh_terms: D002675:Child, Preschool; D005112:Extracorporeal Circulation; D005167:Factor VII / Q000008:administration & dosage / Q000032:analysis / Q000235:genetics; D005168:Factor VII Deficiency; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006438:Hemodilution; D006801:Humans; D008297:Male; D011182:Postoperative Care; D011300:Preoperative Care; D011517:Prothrombin Time
chemical_list: D005167:Factor VII