Neural organization of the locomotive oscillator.
We study the relation of neural development, organization, and activity to behavior. We provide a model of the locomotive oscillator, a neural system supplying alternating stimulation to extensor and flexor muscles creating an oscillatory motion. We propose a protocol by which this neural system starting from unstructured, unconnected neural populations develops structure and function. The protocol is studied by both computer simulation and mathematical analysis. Our main results are 1. The locomotive oscillator self-organizes and maintains its organization, assuming certain properties of the neural populations. 2. Imperfections disturbing the functional adequacy of the neural populations may lead to the deterioration and disappearance of the oscillatory behavior. 3. The locomotive oscillator may fail to organize if the development is not staged in time.
Willner
B E
BE
IBM Research Division, T.J. Watson Research Center, Yorktown Heights, NY 10598.
Miranker
W L
WL
Lu
C P
CP
D000818:Animals; D001683:Biological Clocks / Q000502:physiology; D003198:Computer Simulation; D003491:Cybernetics; D008124:Locomotion / Q000502:physiology*; D008959:Models, Neurological; D009046:Motor Neurons / Q000502:physiology; D009415:Nerve Net / Q000033:anatomy & histology / Q000254:growth & development / Q000502:physiology; D009420:Nervous System / Q000033:anatomy & histology / Q000254:growth & development; D009424:Nervous System Physiological Phenomena; D013569:Synapses / Q000502:physiology