Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome.
Yohimbine is an indole alkaloid obtained from the yohimbe tree, a common tree in West Africa. We describe a forty-two-year black man in whom a generalized erythrodermic skin eruption, progressive renal failure, and lupus-like syndrome developed following treatment with the drug, yohimbine. A literature review failed to reveal any reported association of these side effects. We review current information on yohimbine's use in male impotence, reported side effects, and its role as a drug allergen.
Sandler
B
B
Department of Internal Medicine, Wayne State University, Detroit, Michigan.
Aronson
P
P
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D003875:Drug Eruptions / Q000209:etiology*; D007172:Erectile Dysfunction / Q000188:drug therapy; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008297:Male; D015016:Yohimbine / Q000009:adverse effects*
D015016:Yohimbine