Sequence of the Schizosaccharomyces pombe gtp1 gene and identification of a novel family of putative GTP-binding proteins.
A new gene, gtp1, has been identified by sequence analysis in Schizosaccharomyces pombe. The open reading frame was identified downstream from the stf1 locus. The deduced GTP1 protein has strong sequence similarity to a family of putative GTP-binding proteins from Halobacterium cutirubrum, Bacillus subtilis, Drosophila melanogaster and mouse. The conserved P-loop phosphate-binding motif places gtp1 in a family separate from previously described groups of such proteins.
Hudson
J D
JD
Department of Biology, Queen's University, Kingston, Ontario, Canada.
Young
P G
PG
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D016384:Consensus Sequence; D004271:DNA, Fungal; D004330:Drosophila / Q000235:genetics; D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics*; D019204:GTP-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D005800:Genes, Fungal; D051379:Mice; D008969:Molecular Sequence Data; D020559:Monomeric GTP-Binding Proteins; D005810:Multigene Family; D011487:Protein Conformation; D012568:Schizosaccharomyces / Q000235:genetics*; D029702:Schizosaccharomyces pombe Proteins; D017386:Sequence Homology, Amino Acid
D004271:DNA, Fungal; D005656:Fungal Proteins; D029702:Schizosaccharomyces pombe Proteins; D019204:GTP-Binding Proteins; C080520:GTP1 protein, S pombe; D020559:Monomeric GTP-Binding Proteins