title: Fumonisin toxicity in turkey poults.
abstract: The effects of dietary fumonisin B1 were evaluated in young turkey poults. The experimental design consisted of 3 treatments, with 24 female turkey poults allotted randomly per treatment. Day-old poults were fed diets containing 0 mg (feed control), 100 mg, and 200 mg fumonisin B1/kg feed for 21 days. Body weight gains and efficiency of feed conversion decreased linearly with increasing dietary fumonisin. Liver, kidney, and pancreas weights increased linearly with increasing dietary fumonisin, and spleen and heart weights decreased. Serum aspartate aminotransferase levels increased with increasing dietary fumonisin, and serum cholesterol; alkaline phosphatase, mean cell volume, and mean cell hemoglobin all decreased. Biliary hyperplasia, hypertrophy of Kupffer's cells, thymic cortical atrophy, and moderate widening of the proliferating and degenerating hypertrophied zones of tibial physes were present in poults fed diets containing fumonisin B1. Results indicate that fumonisin B1, from Fusarium moniliforme culture material, is toxic in young poults, and the poult appears to be more sensitive to fumonisin than the broiler chick.
authors: Animal Sciences Department, University of Missouri, Columbia 65211.
authors: T S
authors: TS
authors: Weibking
authors: D R
authors: DR
authors: Ledoux
authors: T P
authors: TP
authors: Brown
authors: G E
authors: GE
authors: Rottinghaus
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001284:Atrophy; D001835:Body Weight / Q000187:drug effects; D002274:Carcinogens, Environmental / Q000633:toxicity; D002784:Cholesterol / Q000097:blood; D005260:Female; D037341:Fumonisins; D006321:Heart / Q000033:anatomy & histology / Q000187:drug effects; D007668:Kidney / Q000033:anatomy & histology / Q000187:drug effects / Q000473:pathology; D008099:Liver / Q000033:anatomy & histology / Q000187:drug effects / Q000473:pathology; D009183:Mycotoxins / Q000633:toxicity*; D009206:Myocardium / Q000473:pathology; D009929:Organ Size / Q000187:drug effects; D010179:Pancreas / Q000033:anatomy & histology / Q000187:drug effects / Q000473:pathology; D013154:Spleen / Q000033:anatomy & histology / Q000187:drug effects / Q000473:pathology; D013950:Thymus Gland / Q000187:drug effects / Q000473:pathology; D014422:Turkeys; D015430:Weight Gain
chemical_list: D002274:Carcinogens, Environmental; D037341:Fumonisins; D009183:Mycotoxins; C056933:fumonisin B1; D002784:Cholesterol; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase