[An open study on the clinical efficacy of citicoline in patients with chronic cerebral vasculopathy].
In this study we evaluated the safety/efficacy of citicoline in 30 patients affected by atherosclerotic processes with cerebral localization. Aim of this study was to confirm, from a clinical point of view, the efficacy of citicoline in increasing blood flow in the vascular zone and in exerting a trophic action on cerebral cells improving the symptoms related to the chronic cerebrovasculopathy. Therapeutic effect was evaluated, by means of subjective parameters, at the beginning, during and at the end of the study. The results obtained was statistically analyzed confirming the efficacy of citicoline on the subjective symptomatology. Safety was excellent in all cases.
Rossi
M
M
Divisione Neurologica, USL 11, Ospedali Civili Sampierdarena Genova.
Zanardi
M
M
D000368:Aged; D000369:Aged, 80 and over; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D002908:Chronic Disease; D003566:Cytidine Diphosphate Choline / Q000627:therapeutic use*; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D003566:Cytidine Diphosphate Choline
Studio in aperto sull'efficacia clinica della citicolina in pazienti affetti da cerebrovasculopatia cronica.