[The action of exogenous RNAse on the cells of lower eukaryotes].
We studied the mechanism of growth-stimulating effect of various compounds using an exogenous RNase-micromycete model and found that the treatment with microdoses of RNase intensified the reproduction of the yeast Candida valida and growth of Aspergillus fumigatus. At the same time the respiration activity of yeast cells and fungal mitochondria as well as succinate dehydrogenase activity increased. The secretion of total protein, cellulase and cellobiase changed in the presence of RNase in the growth medium. Electrophoretic mobility of Candida valida cells enhanced by 20%. The RNase stimulating effect on microbial cells seems to result from changes in characteristics of the cell surface.
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D001232:Aspergillus fumigatus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D001407:Bacillus / Q000201:enzymology; D002175:Candida / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004586:Electrophoresis; D012260:Ribonucleases / Q000494:pharmacology*; D013268:Stimulation, Chemical
D012260:Ribonucleases
Deĭstvie ékzogennoĭ RNKazy na kletku nizshikh éukariot.