title: [Synthesis of nucleoside analogs containing a cis-2-pentene fragment and their triphosphates].
abstract: Acyclic analogs of thymidine, adenine, and cytosine where the ribose moiety is replaced with cis-5-hydroxypenthene, were obtained via condensation of cis-5-acetoxy-1-bromo-2-pentene with nucleic acid bases. Triphosphate derivatives of the new nucleosides were also synthesized to evaluate their action as terminators of DNA synthesis catalyzed by DNA polymerases.
authors: B I
authors: BI
authors: Mitsner
authors: M V
authors: MV
authors: Kochetkov
authors: D V
authors: DV
authors: Filippov
authors: A V
authors: AV
authors: Tsytovich
authors: N B
authors: NB
authors: Diatkina
mesh_terms: D002384:Catalysis; D004247:DNA / Q000096:biosynthesis; D004259:DNA-Directed DNA Polymerase / Q000737:chemistry; D009696:Nucleic Acids / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D013728:Terminator Regions, Genetic
chemical_list: D009696:Nucleic Acids; D009705:Nucleosides; D004247:DNA; D004259:DNA-Directed DNA Polymerase
vernacular_title: Sintez analogov nukleozidov, soderzhashchikh tsis-2-pentenovyĭ fragment, i ikh trifosfatov.