Evaluation of role of upper cervical inspiratory neurons in respiration, emesis and cough.
Upper cervical (C1-3) inspiratory (UCI) propriospinal neurons project to spinal segments containing respiratory motoneurons, but their functional significance is unknown. Bilateral kainic acid injections into this cell column in 12 decerebrate cats (11 paralyzed and artificially ventilated) had no major effect on phrenic, intercostal, and abdominal nerve discharge or EMG activity during (fictive) respiration, vomiting and coughing. Thus, UCI neurons are unessential for activation of major respiratory muscles during these behaviors.
Miller
A D
AD
Rockefeller University, New York, NY 10021.
Yates
B J
BJ
D000005:Abdomen / Q000294:innervation; D000818:Animals; D002415:Cats; D003371:Cough / Q000503:physiopathology*; D003655:Decerebrate State; D004576:Electromyography; D004594:Electrophysiology; D007367:Intercostal Nerves / Q000502:physiology; D007608:Kainic Acid / Q000494:pharmacology; D009333:Neck; D009424:Nervous System Physiological Phenomena; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D010791:Phrenic Nerve / Q000502:physiology; D012119:Respiration / Q000502:physiology*; D013116:Spinal Cord / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D014839:Vomiting / Q000503:physiopathology*
D007608:Kainic Acid