title: [Adverse effect of prolonged formalin fixation on DNA ploidy in paraffin-embedded tissue].
abstract: From retrospective analysis of 174 formalin fixed, paraffin-embedded, HCC tissue samples, the possible correlation was investigated between the CV determined by FCM and the duration of formalin fixation. An adverse effect of prolonged formalin fixation on CV and fluorescence intensity in liver tissue was investigated prospectively in samples from 4 patients.
authors: First Dept. of Surgery, Hyogo College of Medicine.
authors: N
authors: N
authors: Ichikawa
authors: E
authors: E
authors: Okamoto
authors: J
authors: J
authors: Fujimoto
authors: N
authors: N
authors: Yamanaka
authors: T
authors: T
authors: Oriyama
authors: K
authors: K
authors: Furukawa
authors: E
authors: E
authors: Kawamura
authors: T
authors: T
authors: Tanaka
authors: F
authors: F
authors: Tomoda
authors: M
authors: M
authors: Takeuchi
mesh_terms: D004273:DNA, Neoplasm / Q000032:analysis* / Q000235:genetics; D005434:Flow Cytometry; D005557:Formaldehyde / Q000009:adverse effects*; D006801:Humans; D008113:Liver Neoplasms / Q000235:genetics / Q000473:pathology*; D016612:Paraffin Embedding; D011003:Ploidies; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D004273:DNA, Neoplasm; D005557:Formaldehyde