Sequence of the Candida albicans erg7 gene.
The nucleotide sequence of the Candida albicans erg7 gene, which complements erg7 mutants of Saccharomyces cerevisiae and restores oxidosqualene cyclase activity, was determined. The gene encodes a 728-aa protein that displays homology with squalene-hopene cyclase, providing further evidence that erg7 is the gene encoding 2,3-oxidosqualene cyclase.
Roessner
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CA
Department of Chemistry, Texas A & M University, College Station 77843-3255.
Min
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Hardin
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Harris-Haller
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McCollum
J C
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Scott
A I
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D000595:Amino Acid Sequence; D001483:Base Sequence; D002176:Candida albicans / Q000201:enzymology / Q000235:genetics*; D004271:DNA, Fungal; D005800:Genes, Fungal; D019751:Intramolecular Transferases; D007535:Isomerases / Q000235:genetics*; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid
D004271:DNA, Fungal; D007535:Isomerases; D019751:Intramolecular Transferases; C066630:squalene-hopene cyclase; C021924:lanosterol synthase