Low-dose rapamycin potentiates the effects of subtherapeutic doses of cyclosporine to prolong renal allograft survival in the mongrel canine model.
Knight
R
R
Department of Surgery, Mount Sinai Medical School, New York, New York 10029.
Ferraresso
M
M
Serino
F
F
Katz
S
S
Lewis
R
R
Kahan
B D
BD
D000818:Animals; D016572:Cyclosporine / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D004382:Duodenitis / Q000139:chemically induced; D005260:Female; D005756:Gastritis / Q000139:chemically induced; D006085:Graft Survival / Q000187:drug effects*; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced; D011090:Polyenes / Q000008:administration & dosage* / Q000633:toxicity; D020123:Sirolimus; D013997:Time Factors; D014184:Transplantation, Homologous / Q000276:immunology
D011090:Polyenes; D016572:Cyclosporine; D020123:Sirolimus