title: Effect of sialoadenectomy on the carriage of Candida albicans in the mouths of rats.
abstract: Xerostomia provoked in rats by surgical removal of the major salivary glands significantly increased oral carriage of Candida albicans. Five weeks after 3 oral inoculations of 10(8) CFU, C. albicans were found in the mouths in 50% of normal animals but after 8 weeks in none. In xerostomic rats, 100% had oral C. albicans after 5 weeks and after 18 weeks, 66.6% still harboured yeasts. Over the whole experimental period the amount of C. albicans was greater in the mouths of sialoadenectomized than in normal rats.
authors: Department of Oral Pathology, Faculty of Odontology, Piraciacaba-SP, Brazil.
authors: A O
authors: AO
authors: Jorge
authors: M A
authors: MA
authors: Totti
authors: O P
authors: OP
authors: de Almeida
authors: C
authors: C
authors: Scully
mesh_terms: D000818:Animals; D002176:Candida albicans / Q000302:isolation & purification / Q000502:physiology*; D002180:Candidiasis, Oral; D004195:Disease Models, Animal; D008297:Male; D009055:Mouth / Q000382:microbiology*; D051381:Rats; D017208:Rats, Wistar; D012469:Salivary Glands / Q000502:physiology* / Q000601:surgery*; D014987:Xerostomia / Q000150:complications