Annuloplasty with flexible or rigid ring does not alter left ventricular systolic performance, energetics, or ventricular-arterial coupling in conscious, closed-chest dogs.
Eighteen dogs were randomly chosen to undergo mitral annuloplasty with either a Carpentier-Edwards rigid ring (n = 6 in each group) or a Duran-Medtronic flexible ring or to undergo a sham procedure with an operation, but no ring. Tantalum markers were inserted to measure left ventricular volume and geometry. After 1 and 6 weeks, biplane videofluoroscopic images were obtained during steady-state conditions and during vena caval occlusion. Global and regional systolic function was assessed with load-insensitive indexes. Comparison of all three groups and both times (1 and 6 weeks) showed no significant differences among the three groups in global or regional (basal, equatorial, and apical) left ventricular systolic performance. Furthermore, neither type of annuloplasty ring significantly affected left ventricular pump efficiency, ventricular-arterial coupling ratio, or systolic circumferential contraction and rotation of the basal left ventricular sites.
Castro
L J
LJ
Department of Cardiovascular and Thoracic Surgery, Stanford University School of Medicine, CA 94305.
Moon
M R
MR
Rayhill
S C
SC
Niczyporuk
M A
MA
Ingels
N B
NB
Daughters
G T
GT
Derby
G C
GC
Miller
D C
DC
D000818:Animals; D003243:Consciousness; D003971:Diastole; D004285:Dogs; D015150:Echocardiography, Doppler; D006350:Heart Valve Prosthesis / Q000295:instrumentation* / Q000379:methods; D006439:Hemodynamics; D008943:Mitral Valve / Q000502:physiology / Q000601:surgery*; D011182:Postoperative Care; D011474:Prosthesis Design; D011897:Random Allocation; D013599:Systole; D016277:Ventricular Function, Left / Q000502:physiology*