Pharmacological studies on meprobamate incorporation in human beard hair.
The time course of appearance of meprobamate in beard hair after single oral administration (400, 800, or 1200 mg) was monitored in 3 groups of 4 subjects by GC/MS. Meprobamate appeared in beard hair approximately 4-5 days after administration and peaked during the 7-9th day. Drug levels in beard hair appeared to be dose-related.
Kintz
P
P
Institut de Médecine Légale, Strasbourg, France.
Tracqui
A
A
Mangin
P
P
D000284:Administration, Oral; D000328:Adult; D004305:Dose-Response Relationship, Drug; D008401:Gas Chromatography-Mass Spectrometry; D006197:Hair / Q000378:metabolism*; D006801:Humans; D008297:Male; D008620:Meprobamate / Q000008:administration & dosage / Q000493:pharmacokinetics*; D008657:Metabolic Clearance Rate / Q000502:physiology
D008620:Meprobamate