title: Coding of movement direction and amplitude in Parkinson's disease: are they differentially impaired (or unimportant)?
abstract: A recent study suggested that the preparation of movement direction, but not amplitude, may be selectively impaired by Parkinson's disease (PD). The authors examined the reprogramming of direction only, amplitude only, and direction and amplitude together, and included a control condition in which neither parameter was reprogrammed. The findings suggested that neither direction nor amplitude coding was differentially impaired in PD. Thus the structures affected by PD may not be uniquely involved in specifying only the direction or the amplitude of future movements; these structures probably have more complex higher-level roles.
authors: Department of Psychology, Monash University, Melbourne, Australia.
authors: D L
authors: DL
authors: Jones
authors: J G
authors: JG
authors: Phillips
authors: J L
authors: JL
authors: Bradshaw
authors: R
authors: R
authors: Iansek
authors: J A
authors: JA
authors: Bradshaw
mesh_terms: D000368:Aged; D001288:Attention / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009949:Orientation / Q000187:drug effects / Q000502:physiology*; D010300:Parkinson Disease / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D011597:Psychomotor Performance / Q000187:drug effects / Q000502:physiology*; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology*
chemical_list: D007980:Levodopa