Isolated ocular involvement in non-Hodgkin's lymphoma with immunocytochemical evaluation.
We report the case of a patient with isolated ocular involvement and non-Hodgkin's lymphoma (also known as reticulum cell sarcoma). Most non-Hodgkin's central nervous system lymphomas are large cell lymphomas derived from B-cells. The patient initially had iritis OD and vitreous cells OS. Eventually, rubeosis and vitritis developed OD. A systemic workup showed no extraocular lymphoma. Immunocytochemical analysis was done on the vitreous OD and detected a monoclonal B-cell population of large lymphoid cells. This case shows the frequent delay in making the diagnosis of this condition. This diagnosis must be remembered when a patient has vitreous opacities.
Allinson
R W
RW
Department of Ophthalmology, University of Arizona, Tucson 85724.
Stanko
M L
ML
Aguirre
M L
ML
Spier
C M
CM
Kramer
T R
TR
Metrikin
D
D
D005134:Eye Neoplasms / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007500:Iritis / Q000175:diagnosis; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D014822:Vitreous Body / Q000473:pathology