title: [Formation of heat stability of gametes in Drosophila oogenesis and connection of this property with the mutation process].
abstract: It has been demonstrated that heat resistance (and radiosensitivity) of the germ cells at all stages of oogenesis in the females of heat resistant drosophila line (T) is being formed during ontogenesis and depends on the environmental temperature. These characteristics were retained at the stage of imago, even in the cases of temperature changes (from +32 to +25 degrees C, or from +25 to +32 degrees C). The intensity of induced mutagenesis (by X-rays and high temperature) which was evaluated for the frequency of dominant lethal mutations and X-chromosome loss depended on the temperature during development, but depends on no temperature at the time of treating imago with the mutagenic agents. It is suggested to be a result of the participation of heat shock proteins in repair of DNA damages.
authors: M M
authors: MM
authors: Timomirova
authors: O Ia
authors: OIa
authors: Beliatskaia
mesh_terms: D000818:Animals; D002872:Chromosome Deletion; D004330:Drosophila / Q000235:genetics* / Q000502:physiology; D005260:Female; D005799:Genes, Dominant; D005804:Genes, Lethal; D005854:Germ Cells; D006358:Hot Temperature; D016296:Mutagenesis; D009866:Oogenesis / Q000235:genetics*; D014960:X Chromosome
vernacular_title: Formirovanie teploustoĭchivosti gamet v oogeneze u Drozofily i sviaz' étogo svoĭstva s mutatsionnym protsessom.