title: Quantitative evaluation of saccadic and smooth pursuit eye movements. Is it reliable?
abstract: OBJECTIVE
  The authors evaluated the reliability of the coefficients of the (1) amplitude/duration and (2) amplitude/peak velocity relationships of the mean precision values and the mean latency values (saccadic eye movements) and the coefficients of the target velocity/gain relationship (smooth pursuit eye movements). They computed test-retest maximum variability limits for these parameters.
  
  
  METHODS
  After a 1-week interval, saccadic and smooth pursuit eye movements were recorded twice from 20 healthy subjects; 12 of these subjects underwent a third recording session. The estimate of the intraclass coefficient of reliability, R, was adopted to evaluate the reliability of eye movement quantitative analysis.
  
  
  RESULTS
  The data demonstrated that the reliability was fairly good for the amplitude/peak velocity relationship, was good for the precision, and was excellent for the amplitude/duration, the target velocity/gain relationships, and the latency.
  
  
  CONCLUSIONS
  Quantitative analysis of both saccadic and smooth pursuit eye movements is reliable. One statistic used to estimate reliability, ie, the within-subjects mean square value, also enables the determination of test-retest normal variability values for both the variances and the differences of measurements.
authors: Istituto Neurologico Fondazione C. Mondino, Pavia, Italy.
authors: M
authors: M
authors: Versino
authors: G
authors: G
authors: Castelnovo
authors: R
authors: R
authors: Bergamaschi
authors: A
authors: A
authors: Romani
authors: G
authors: G
authors: Beltrami
authors: D
authors: D
authors: Zambarbieri
authors: V
authors: V
authors: Cosi
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D004585:Electrooculography / Q000379:methods*; D005133:Eye Movements; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012438:Saccades / Q000502:physiology*; D012680:Sensitivity and Specificity