[Expression of the v-src oncogene in Escherichia coli affects the rate of cell growth and leads to phosphorylation of cellular proteins].
The possible influence of expression of v-src oncogene harboring tyrosine-specific protein kinase activity on the physiological state of E. coli cells, carrying plasmid which expresses src oncoprotein was studied. The realization of this activity in the cells brings to the phosphorylation of tyrosine in some additional cellular proteins and, as a consequence, to an increased proliferative activity of cells expressing src oncoprotein.
Ambartsumian
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Nalbandian
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Favorova
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Tatosian
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D001426:Bacterial Proteins / Q000378:metabolism*; D002455:Cell Division / Q000235:genetics; D004269:DNA, Bacterial / Q000096:biosynthesis; D004926:Escherichia coli; D015688:Oncogene Protein pp60(v-src) / Q000235:genetics*; D010766:Phosphorylation; D014443:Tyrosine / Q000378:metabolism
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D014443:Tyrosine; D015688:Oncogene Protein pp60(v-src)
Ekspressiia onkogena v-src v Escherichia coli vliiaet na skorost' rostakletok i privodit k fosforilirovaniiu kletochnykh belkov.