title: Digital geometric measurements in comparison to cinefilm analysis of coronary artery dimensions.
abstract: Six months follow-up post-PTCA angiograms from 31 patients were acquired digitally and on cinefilm and used for a comparison of geometric coronary measurements at the site of the previous dilatation. On 70 images of 34 coronary segments quantitative analysis was performed both on-line, using the Automated Coronary Analysis package of the Philips Digital Cardiac Imaging System (DCI, pixel matrix 512 x 512) and off-line, using the Cardiovascular Angiography Analysis System (CAAS). With the CAAS a cine-video conversion is performed and a 6.9 x 6.9 mm region of interest from the 18 x 24 mm cineframe is digitized into a 512 x 512 pixel matrix. In both systems the vascular contours are assessed by means of operator-independent edge detection algorithms. The angiographic catheter was used for calibration. Best agreement between DCI and CAAS was found for obstruction diameter and minimal luminal diameter, respectively (r = 0.82; y = 0.12 + 0.97x; SEE = 0.29). The reconstructed reference diameter related to a computed reference contour yields lower correlation (r = 0.76; y = 0.27 + 0.91x; SEE = 0.37). Worst results were obtained from the relative measure of percent diameter stenosis as well as from the derived parameter of plaque area. The on-line digital approach of geometric coronary assessments provides good agreement with cinefilm analysis when direct measurements of coronary dimensions are applied.
authors: Thoraxcenter, Erasmus University Rotterdam, The Netherlands.
authors: J
authors: J
authors: Haase
authors: S K
authors: SK
authors: Nugteren
authors: E
authors: E
authors: Montauban van Swijndregt
authors: C J
authors: CJ
authors: Slager
authors: C
authors: C
authors: Di Mario
authors: P J
authors: PJ
authors: de Feyter
authors: P W
authors: PW
authors: Serruys
mesh_terms: D000465:Algorithms; D015906:Angioplasty, Balloon, Coronary; D002932:Cineangiography; D017023:Coronary Angiography / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000628:therapy; D003331:Coronary Vessels / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007548:Isosorbide Dinitrate
chemical_list: D007548:Isosorbide Dinitrate