The effect of nifedipine [correction of nifidipine] and cimetidine on the haemodynamics of Egyptian bilharzial pulmonary hypertension.
The pathogenesis of bilharzial pulmonary hypertension differs from the hypoxic type of pulmonary hypertension. Nifedipine [corrected] a calcium channel blocker was tried as a treatment for lowering pulmonary artery pressure. Nifedipine [corrected] 20 mg sublingually was found to lower the pulmonary artery pressure but not to a statistically significant level. No significant changes before and after 200 mg cimetidine intravenous, were seen.
el Hawy
A M
AM
Department of Tropical Medicine, Faculty of Medicine, Al-Azhar University, Imbaba, Cairo.
Negm
I A
IA
el-Rakaybe
A
A
Abdel-Maged
A I
AI
Mansour
R E
RE
D001794:Blood Pressure / Q000187:drug effects*; D002927:Cimetidine / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000209:etiology*; D009543:Nifedipine / Q000494:pharmacology / Q000627:therapeutic use*; D011897:Random Allocation; D012552:Schistosomiasis / Q000150:complications*
D002927:Cimetidine; D009543:Nifedipine