title: Resection for second and third primary lung cancer.
abstract: The continued increasing incidence of bronchogenic carcinoma increases the likelihood that a patient may develop a second or third primary tumor. We have carried out a second thoracotomy for 114 patients who met our criteria of having a new primary lung cancer. These criteria were a different histologic cell type, a tumor-free interval of 24 mo, the second primary in the contralateral lung, or the new tumor in a separate and distinct ipsilateral lobe if the tumor was on the same side. There were 18 patients who had a thoracotomy for a third primary lung cancer and they met the same criteria. There were 73 segmental resections in the 132 thoracotomies, and a conservative resection is important to minimize postoperative complications. Operative mortality for the second resection group of patients was 8.8% (10/114). There was one operative death in the 18 patients undergoing a third resection. The cumulative survival rate following a second resection in 114 patients with metachronous tumors was 33% at 5 yr and 20% at 10 yr. Early detection of a second and third primary lung cancer and surgical resection offers the greatest chance for long-term survival in this group of patients.
authors: Department of Cardiovascular-Thoracic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612.
authors: L P
authors: LP
authors: Faber
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology / Q000601:surgery*; D011013:Pneumonectomy; D012086:Reoperation; D015996:Survival Rate; D013908:Thoracotomy; D013997:Time Factors