Parapapillary chorioretinal atrophy in normal-pressure glaucoma.
Parapapillary chorioretinal atrophy has been shown to be associated with glaucomatous optic nerve damage. We sought to determine whether eyes with normal-pressure glaucoma have an unusually large parapapillary atrophy as compared to eyes with primary open-angle glaucoma. Color stereoscopic optic disk photographs of 34 patients with normal-pressure glaucoma and 283 patients with primary open-angle glaucoma were morphometrically analyzed. Both groups were matched for neuroretinal rim area and visual field loss. Severely myopic eyes were excluded. The parapapillary atrophy was differentiated into a peripheral Zone Alpha with irregular pigmentation and a central Zone Beta with visible sclera. Zones Alpha and Beta did not differ significantly between the two groups in either frequency or size. Eyes with normal-pressure glaucoma do not have an abnormally large parapapillary atrophy as compared to eyes with primary open-angle glaucoma, which is diagnostically and pathogenetically important.
Jonas
J B
JB
Department of Ophthalmology, University Erlangen-Nürnberg, Germany.
Xu
L
L
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001284:Atrophy; D002829:Choroid / Q000473:pathology*; D005260:Female; D005901:Glaucoma / Q000473:pathology* / Q000503:physiopathology; D005902:Glaucoma, Open-Angle / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D011897:Random Allocation; D012160:Retina / Q000473:pathology*