Evaluation of extravascular thermal volume in the lung in dogs with endotoxin-induced shock by double indicator dilution method using heat and sodium ions.
Accuracy assessment was undertaken under varying hemodynamic conditions for a lung water volume measurement device which is based on the principle of a double indicator dilution method using heat and sodium ions. Changes in extravascular thermal volume were investigated in dogs with endotoxin-induced shock. The isoproterenol- or propranolol-induced changes in hemodynamics had no effect on the measurement. This confirmed the high accuracy of this measuring method. The measurement revealed a tendency for the extravascular thermal volume to gradually increase (p < 0.05) during endotoxin shock. This confirmed the gradual progression of pulmonary edema during endotoxin shock.
Tagawa
M
M
Division of Veterinary Surgery, Nippon Veterinary and Animal Science University, Tokyo, Japan.
Okano
S
S
Hara
Y
Y
Ejima
H
H
Motoyoshi
S
S
Urakawa
N
N
Furukawa
K
K
Onda
M
M
Ogawa
R
R
D000818:Animals; D004283:Dog Diseases / Q000503:physiopathology*; D004285:Dogs; D015633:Extravascular Lung Water; D006439:Hemodynamics / Q000502:physiology; D007201:Indicator Dilution Techniques / Q000662:veterinary*; D008176:Lung Volume Measurements / Q000379:methods / Q000662:veterinary*; D012772:Shock, Septic / Q000503:physiopathology / Q000662:veterinary*; D012964:Sodium; D013815:Thermodilution / Q000662:veterinary
D012964:Sodium