[Management of recurrent genital herpes virus infections in gynecology and obstetrics].
Continuous oral therapy with acyclovir (200 mg four times a day or 400 mg twice daily) has been shown to be safe and effective in reducing recurrence of genital herpes by 74-93%. Continuing therapy appears to be safe, even when used for up to 4 years. When an episode of genital herpes is diagnosed in term pregnancy, cesarean section should be considered, even if intrauterine infection is possible until the rupture of membranes. The efficacy of suppressive therapy in term pregnancy to reduce the cesarean section rate is the objective of ongoing studies.
Reichel
R P
RP
I. Universitäts-Frauenklinik, Wien, Osterreich.
D000212:Acyclovir / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006558:Herpes Genitalis / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D012008:Recurrence
D000212:Acyclovir
Management rezidivierender genitaler Herpesinfektionen in Gynäkologie und Geburtshilfe.