title: Effects of p-chloroamphetamine (PCA) on ejaculation in aged rats.
abstract: In general, sexual activity in normal animals declines with increasing age. In aged male rats, for example, no ejaculation occurs when paired with receptive females. The ejaculatory response induced by p-chloroamphetamine (PCA) in aged adult rats, 14 to 18 months of age, was observed. The animals were treated intraperitoneally with PCA. The ejaculation rates were 0.28.6, 57.1 and 100% at doses of 0.3125, 0.625, 1.25 and 2.5 mg/kg, respectively. These animals, with a few exceptions, showed an ejaculation within 2 hrs of PCA injection. These data for aged adults are similar to those for young adults.
authors: Department of Laboratory Animal Science, Nippon Veterinary and Animal Science University, Tokyo, Japan.
authors: T R
authors: TR
authors: Saito
authors: R
authors: R
authors: Hokao
authors: S
authors: S
authors: Aoki
authors: Y
authors: Y
authors: Wakafuji
authors: K W
authors: KW
authors: Takahashi
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D000830:Animals, Laboratory; D004542:Ejaculation / Q000187:drug effects*; D005260:Female; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D010133:p-Chloroamphetamine / Q000494:pharmacology*
chemical_list: D010133:p-Chloroamphetamine