AB023, novel polyene antibiotics. I. Taxonomy of the producing organism, fermentation and antifungal activity.
AB023 is a complex of polyene antibiotics produced by an actinomycete, SD581, which was isolated from a Kenyan soil sample. The two main components, pentaene antibiotics AB023a and AB023b, have antifungal activity against some phytopathogenic fungi, particularly against Botrytis cinerea (MIC of 5 micrograms/ml).
Cidaria
D
D
Istituto Guido Donegani, ENICHEM, Novara, Italy.
Borgonovi
G
G
Pirali
G
G
D000935:Antifungal Agents / Q000096:biosynthesis / Q000302:isolation & purification* / Q000494:pharmacology; D005285:Fermentation; D005658:Fungi / Q000187:drug effects; D007783:Lactones / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D011090:Polyenes / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D013302:Streptomyces / Q000145:classification / Q000378:metabolism*
D000935:Antifungal Agents; D007783:Lactones; D011090:Polyenes