The VP35 and VP40 proteins of filoviruses. Homology between Marburg and Ebola viruses.
The fragments of genomic RNA sequences of Marburg (MBG) and Ebola (EBO) viruses are reported. These fragments were found to encode the VP35 and VP40 proteins. The canonic sequences were revealed before and after each open reading frame. It is suggested that these sequences are mRNA extremities and at the same time the regulatory elements for mRNA transcription. Homology between the MBG and EBO proteins was discovered.
Bukreyev
A A
AA
Institute of Molecular Biology, Koltsovo, Novosibirsk Region, Russian Federation.
Volchkov
V E
VE
Blinov
V M
VM
Netesov
S V
SV
D000595:Amino Acid Sequence; D001483:Base Sequence; D004279:DNA, Viral; D029043:Ebolavirus / Q000235:genetics*; D029024:Marburgvirus / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D012367:RNA, Viral / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000235:genetics*; D054334:Viral Regulatory and Accessory Proteins
D004279:DNA, Viral; D012367:RNA, Viral; C080980:VP35 protein, filovirus; C080981:VP40 protein, virus; D014763:Viral Matrix Proteins; D014764:Viral Proteins; D054334:Viral Regulatory and Accessory Proteins