title: Glucose and zinc concentration influence fusarin C synthesis, ethanol synthesis and lipid composition in Fusarium moniliforme submerged cultures.
abstract: A fusarin C-producing Fusarium moniliforme strain was grown in submerged culture with defined media containing differing amounts of glucose (30 g/l or 90 g/l) and zinc (5 ppb or 3200 ppb). The influence of zinc on fusarin C synthesis and lipid composition was dependent on the initial glucose concentration. In cultures supplied with 30 g/l glucose, zinc inhibited fusarin C and lipid synthesis by diverting common substrates to ethanol synthesis. Zinc-supplemented cultures with 90 g/l glucose had ample carbon substrate to produce both ethanol and fusarin C. More total lipid with a higher unsaturated fatty acid content (more oleic acid and less stearic acid) was found in F. moniliforme biomass produced in zinc-deficient media.
authors: Fermentation Biochemistry Research, USDA Agricultural Research Service, Peoria, Illinois 61604.
authors: M A
authors: MA
authors: Jackson
authors: A C
authors: AC
authors: Lanser
mesh_terms: D000431:Ethanol / Q000378:metabolism*; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism; D005670:Fusarium / Q000187:drug effects / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry; D011090:Polyenes / Q000378:metabolism*; D015032:Zinc / Q000494:pharmacology
chemical_list: D005227:Fatty Acids; D008055:Lipids; D011090:Polyenes; D000431:Ethanol; C041403:fusarin C; D005947:Glucose; D015032:Zinc