Appenolides A-C: three new antifungal furanones from the coprophilous fungus Podospora appendiculata.
Appenolides A [1], B [2], and C [3], three new antifungal 2(5H)-furanones, have been isolated from liquid cultures of the coprophilous fungus Podospora appendiculata (UAMH 7225) by repeated preparative tlc on Si gel. The structures were assigned on the basis of nmr and ms data.
Wang
Y
Y
Department of Chemistry, University of Iowa, Iowa City 52242.
Gloer
J B
JB
Scott
J A
JA
Malloch
D
D
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry* / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents; C080967:appenolide A; C080968:appenolide B; C080969:appenolide C; D015107:4-Butyrolactone