[Neurological side effects following vaccination of early-summer meningoencephalitis. Case report and experiences of the Swiss Center for Adverse Drug Effects].
Two weeks after vaccination against tick-born encephalitis (TBE) a 69-year-old patient developed subacute myelo-polyradiculitis. The neurological symptoms subsided after a few weeks. Alerted by this observation, we scanned the database of the Swiss Drug Monitoring Center (SANZ) for similar case reports. Of twenty spontaneous reports 11 concerned neurological side effects closely related to TBE vaccination. We conclude that TBE vaccination is associated with substantial neurological side effects and should, therefore, remain restricted to individuals at high risk for TBE.
Goerre
S
S
Medizinische Klinik, Kantonsspital Chur.
Kesselring
J
J
Hartmann
K
K
Kuhn
M
M
Reinhart
W H
WH
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D000075202:Contraindications; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D004675:Encephalitis, Tick-Borne / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology; D011128:Polyradiculopathy / Q000209:etiology*; D012307:Risk Factors; D014765:Viral Vaccines / Q000009:adverse effects*
D014765:Viral Vaccines
Neurologische Nebenwirkungen nach Impfung gegen die Frühsommer-Meningo-Enzephalitis. Fallbericht und Erfahrungen der Schweizerischen Arzneimittel-Nebenwirkungszentrale (SANZ).