Reflex blepharospasm associated with bilateral basal ganglia lesion.
A patient with a bilateral striatal lesion secondary to anoxia presented reflex blepharospasm associated with parkinsonism and dystonia in the limbs. The blink reflex excitability curve was enhanced and the R-2 response prolonged as in patients with essential blepharospasm. The findings in this patient support the notion that blepharospasm may be secondary to basal ganglia dysfunction through abnormal facilitation of reticular formation neurons controlling facial nucleus motoneuron excitability.
Larumbe
R
R
Department of Neurology, University of Navarra Medical School, Pamplona, Spain.
Vaamonde
J
J
Artieda
J
J
Zubieta
J L
JL
Obeso
J A
JA
D000293:Adolescent; D001480:Basal Ganglia Diseases / Q000175:diagnosis / Q000503:physiopathology*; D001764:Blepharospasm / Q000175:diagnosis / Q000503:physiopathology*; D001767:Blinking / Q000502:physiology*; D002421:Caudate Nucleus / Q000503:physiopathology; D002544:Cerebral Infarction / Q000175:diagnosis / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology*; D004421:Dystonia / Q000175:diagnosis / Q000503:physiopathology; D004576:Electromyography; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000175:diagnosis / Q000503:physiopathology*; D007431:Intraoperative Complications / Q000175:diagnosis / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D010302:Parkinson Disease, Secondary / Q000175:diagnosis / Q000503:physiopathology; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology; D011699:Putamen / Q000503:physiopathology