Erythema nodosum associated with all-trans-retinoic acid in the treatment of acute promyelocytic leukemia.
A patient with acute promyelocytic leukemia is presented. During treatment with all-trans-retinoic acid, erythema nodosum developed. Treatment with all-trans-retinoic acid was continued, the erythema nodosum resolved with steroid treatment, and a complete remission was attained. This case is the first report of erythema nodosum associated with all-trans-retinoic acid.
Hakimian
D
D
Department of Medicine, Robert H. Lurie Cancer Center of Northwestern University, Chicago, Illinois.
Tallman
M S
MS
Zugerman
C
C
Caro
W A
WA
D000328:Adult; D004893:Erythema Nodosum / Q000139:chemically induced*; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D014212:Tretinoin / Q000009:adverse effects*
D014212:Tretinoin