title: [Suppression of macrophage subpopulations in post-traumatic osteomyelitis].
abstract: Similar to other chronic inflammatory diseases such as rheumatoid arthritis the distribution of macrophage subtypes seems to be disturbed in post-traumatic osteomyelitis. This atypical distribution is clearly locally restricted in osteomyelitis. 27E10-positive macrophages found only during the acute phase of inflammation were reduced in 39%, the 25F9-positive subtype, predominating in the late stage of inflammation, was missing in 33%. The antiinflammatory macrophage RM3/1 was decreased in 40% of the osteomyelitis biopsies. Local suppression of macrophage subsets has to be discussed as one of the reasons for the persistence of chronic inflammatory processes in osteomyelitis.
authors: Orthopädische Klinik, RWTH Aachen.
authors: K M
authors: KM
authors: Peters
authors: G
authors: G
authors: Zwadlo-Klarwasser
authors: K
authors: K
authors: Koberg
authors: T
authors: T
authors: Rosendahl
authors: K W
authors: KW
authors: Zilkens
authors: W
authors: W
authors: Schmutzler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008264:Macrophages / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000473:pathology*
vernacular_title: Verminderung von Makrophagensubpopulationen bei der posttraumatischen Osteomyelitis.