Darrow-Gamble disease: ultrasonographic and radiographic findings.
A case of Darrow-Gamble disease is presented with review of the radiographic and ultrasonographic appearance of this rare cause of profound chronic diarrhea beginning at birth. The disease is caused by a defect of active intestinal chloride transport which results in a large loss of the electrolytes and water. To prevent growth retardation and renal involvement an adequate replacement therapy is necessary. This uncommon anomaly was detected by ultrasound 3 weeks before delivery. Both sonography and radiography were useful diagnostic tools in the postnatal period. The clinical features of the lesion are also discussed.
Poggiani
C
C
Neonatal Intensive Care Unit, Ospedali Riuniti, Bergamo, Italy.
Auriemma
A
A
Menghini
P
P
Lando
B
B
Bonhoeffer
P
P
Colombo
A
A
D002712:Chlorides / Q000378:metabolism; D003968:Diarrhea, Infantile / Q000151:congenital / Q000175:diagnosis* / Q000378:metabolism; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D014057:Tomography, X-Ray Computed; D016216:Ultrasonography, Prenatal; D014883:Water-Electrolyte Imbalance / Q000151:congenital / Q000175:diagnosis* / Q000378:metabolism
D002712:Chlorides