Urinary excretion of 6-hydroxymethylpterin in brain tumours.
The urinary 6-hydroxymethylpterin(Pt-6-CH2OH) excretion was determined in 87 patients with brain tumours and in 50 control patients. The Pt-6-CH2OH levels were significantly elevated in all patients with tumours. No difference was observed when malignant tumours were compared with benign neoplasms. Following therapy, the Pt-6-CH2OH levels were partially reduced when compared with control patients and their pre-operative values.
Manjula
S
S
Department of Biochemistry, Kasturba Medical College and Hospital, Manipal, India.
Aroor
A R
AR
Raja
A
A
Rao
S
S
Rao
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000652:urine*; D002648:Child; D005260:Female; D005910:Glioma / Q000652:urine; D006801:Humans; D008297:Male; D008579:Meningioma / Q000652:urine; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000652:urine; D011622:Pterins / Q000652:urine*
D011622:Pterins; C013044:6-hydroxymethylpterin