Linear dichroism demonstrates that the bases in poly[d(AC)].poly[d (GT)] and poly[d(AG)].poly[d(CT)] are inclined from perpendicular to the helix axis.
Flow linear dichroism is used to measure specific inclinations for each of the four bases in poly[d(AC)].poly[d(GT)] and poly[d(AG)].poly[d(CT)] in both the B and A forms. For the B form in solution the bases are found to have a sizable inclination. Inclination is increased in the A form, as expected. In all cases the pyrimidines are more inclined than the purines.
Kang
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Department of Biochemistry and Biophysics, Oregon State University, Corvallis 97331-6503.
Johnson
W C
WC
D000225:Adenine / Q000737:chemistry; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003596:Cytosine / Q000737:chemistry; D006147:Guanine / Q000737:chemistry; D008968:Molecular Conformation; D011089:Polydeoxyribonucleotides / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods; D013941:Thymine / Q000737:chemistry
D011089:Polydeoxyribonucleotides; C050366:poly(dG-dA)n.poly(dC-dT)n; C033927:poly(dA-dC).poly(dG-dT); D006147:Guanine; D003596:Cytosine; D000225:Adenine; D013941:Thymine