Efficacy of closantel against fenbendazole and levamisole resistant Haemonchus contortus in small ruminants.
Sheep infected with a fenbendazole resistant strain of Haemonchus contortus and goats with a levamisole resistant strain of the same parasite were used to evaluate the anthelmintic efficacy of closantel. Closantel at the rate of 10 mg/kg body weight was 100% effective against the 2 resistant strains of the parasite as indicated by faecal egg count and worm reduction. The efficacy of fenbendazole in sheep and of levamisole in goats was 56.68 and 76.90%, respectively.
Uppal
R P
RP
College of Veterinary Sciences, CCS Haryana Agricultural University, Hisar, India.
Yadav
C L
CL
Bhushan
C
C
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004351:Drug Resistance; D005273:Fenbendazole; D015511:Goat Diseases / Q000188:drug therapy*; D006041:Goats; D006188:Haemonchiasis / Q000188:drug therapy / Q000662:veterinary*; D006189:Haemonchus / Q000187:drug effects*; D007978:Levamisole; D012458:Salicylanilides / Q000627:therapeutic use*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*; D016896:Treatment Outcome
D000871:Anthelmintics; D012458:Salicylanilides; D007978:Levamisole; D005273:Fenbendazole; C023342:closantel