Tall cell carcinoma of the thyroid gland.
Tall cell carcinoma of the thyroid gland is an aggressive variant of papillary carcinoma with a respectable 20% to 25% lethality. Its histologic features are characterized by a basal orientation of nuclei, abundant eosinophilic or oxyphilic cytoplasm, and a cellular height-width ratio greater than 2:1. These distinguish it from another aggressive variant, columnar cell carcinoma, which has a stratification of its nuclei and scant cellular cytoplasm.
Hicks
M J
MJ
University of Texas M.D. Anderson Cancer Center, Houston 77030.
Batsakis
J G
JG
D002291:Carcinoma, Papillary / Q000145:classification / Q000473:pathology*; D006801:Humans; D009361:Neoplasm Invasiveness; D013964:Thyroid Neoplasms / Q000145:classification / Q000473:pathology*