Trisomy 13 (Patau syndrome) with an 11-year survival.
Trisomy 13 is very rare in live-born children. Only a small number of these children survive the first year and very few cases are reported to live longer. Survival time depends partly on the cytogenetic findings--full trisomy 13 or trisomy 13 mosaicism--and partly on the existence of serious somatic malformations. We report on a 11-year-old girl with full trisomy 13. In this case, missing cerebral and cardiovascular malformations probably allowed the long survival.
Zoll
B
B
Institut für Humangenetik, Universität Göttingen, FRG.
Wolf
J
J
Lensing-Hebben
D
D
Pruggmayer
M
M
Thorpe
B
B
D000015:Abnormalities, Multiple / Q000235:genetics*; D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D002882:Chromosomes, Human, Pair 13; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics; D017880:Limb Deformities, Congenital; D008297:Male; D008831:Microcephaly / Q000235:genetics; D012535:Scalp / Q000002:abnormalities; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014314:Trisomy