title: Adenine dinucleotide-mediated cytosolic free Ca2+ oscillations in single hepatocytes.
abstract: Single rat hepatocytes microinjected with aequorin respond to Ca(2+)-mobilizing agonists, including ADP and ATP, with oscillations in cytosolic free Ca2+. We show here that single rat hepatocytes also respond to the adenine dinucleotides Ap3A and Ap4A with Ca2+ oscillations which resemble those induced by ADP and ATP.
authors: Department of Human Anatomy and Cell Biology, University of Liverpool, UK.
authors: A K
authors: AK
authors: Green
authors: C J
authors: CJ
authors: Dixon
authors: A G
authors: AG
authors: McLennan
authors: P H
authors: PH
authors: Cobbold
authors: M J
authors: MJ
authors: Fisher
mesh_terms: D000331:Aequorin; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015226:Dinucleoside Phosphates / Q000502:physiology*; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D015226:Dinucleoside Phosphates; D000331:Aequorin; C020733:diadenosine tetraphosphate; C011440:diadenosine triphosphate; D002118:Calcium