title: Estimating the seroincidence of HIV-1 in the general adult population in Kigali, Rwanda.
abstract: OBJECTIVE
  To estimate the seroincidence of HIV-1 infection in the general adult population of Kigali, Rwanda.
  
  
  METHODS
  Repeated standardized cross-sectional studies.
  
  
  METHODS
  Two urban prenatal clinics.
  
  
  METHODS
  A total of 4486 consecutive pregnant women consulting in 1989 and 1990.
  
  
  METHODS
  Prevalence of HIV-1 antibodies.
  
  
  RESULTS
  HIV seropositivity increased by 3-5% annually over this period, indicating that it has not reached a plateau in this sentinel population. The percentage infection rates, calculated using two complementary methods, were 26.2-30.7% in 1990. Extrapolating these results to the general population of Kigali, we estimate that 2300-3800 new infections in young women and 3600-6100 new infections in young men occur annually among the total population of 350,000 in Kigali.
  
  
  CONCLUSIONS
  A new HIV infection occurred in an adult every 50-90 min, on average, in Kigali during 1989-1990, while every 6-7 h a baby with maternally acquired HIV infection was born. Our HIV surveillance system, which is based on prenatal sentinel posts, is a useful tool for monitoring the progression of the HIV epidemic in Kigali.
authors: Rwanda National AIDS Control Program, Ministry of Health, Kigali.
authors: A
authors: A
authors: Bucyendore
authors: P
authors: P
authors: Van de Perre
authors: E
authors: E
authors: Karita
authors: A
authors: A
authors: Nziyumvira
authors: I
authors: I
authors: Sow
authors: E
authors: E
authors: Fox
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology / Q000635:transmission; D015528:HIV Seroprevalence; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D012432:Rwanda / Q000453:epidemiology