[The origin of fibrinogen in megakaryocytes and blood platelets].
Fibrinogen is involved in platelet aggregation and clot formation. It is mainly synthesized by hepatocytes. The additional, small pool of this glycoprotein is known to exist in the alpha granules of bone marrow megakaryocytes and blood platelets. Up-date of the origin of fibrinogen in these cells has been discussed.
Podolak-Dawidziak
M
M
Kliniki Hematologii i Chorób Rozrostowych Krwi Akademii Medycznej, Wrocławiu.
D000818:Animals; D001792:Blood Platelets / Q000378:metabolism*; D005340:Fibrinogen / Q000096:biosynthesis*; D006801:Humans; D008533:Megakaryocytes / Q000378:metabolism*
D005340:Fibrinogen
Pochodzenie fibrynogenu megakariocytów i płytek krwi.