title: Laser welding of fascial grafts and its potential application in tympanoplasty: an animal model.
abstract: This study evaluates the welding effect of argon laser on fascial grafts and its potential application in tympanoplasty. An animal model was designed so that surgically induced perforations of the lumbar fascia of the animals were grafted in an underlay fashion. Each graft was "spot welded" around the circumference of the perforation using a hand-held argon laser. Various lasing parameters were used on different grafts. Control perforations were grafted but not welded. A total of 96 perforations was studied. Weld sites were evaluated both histologically and by tensile strength measurement at the end of surgery, and at 7, 14, and 21 days postoperatively. Comparison with controls showed a higher tensile strength for welded grafts, which was most significant in the early postoperative period (p < 0.001). Histologically, it seems that the basic mechanism of fascial welding involves liquification and denaturation of extravasated proteins at the weld sites. Correlation between the extent of thermal damage on the tissues and the various lasing parameters is described. Based on the well-documented safety of argon laser in otologic surgery, and the successful welding of fascial grafts in this study, argon laser may prove beneficial in welding temporalis fascia grafts in tympanoplasty.
authors: Department of Otolaryngology and Communicative Disorders, Cleveland Clinic Foundation, OH 44195-5034.
authors: E
authors: E
authors: Hanna
authors: I
authors: I
authors: Eliachar
authors: R
authors: R
authors: Cothren
authors: T
authors: T
authors: Ivanc
authors: G
authors: G
authors: Hughes
mesh_terms: D000818:Animals; D005205:Fascia / Q000473:pathology / Q000637:transplantation*; D053685:Laser Therapy; D051381:Rats; D013718:Tensile Strength; D014433:Tympanoplasty; D014945:Wound Healing