title: Acute electrolyte disturbances in coronary sinus during left coronary arteriography in man.
abstract: Electrolyte disturbances, particularly reduction of ionized calcium, induced by iodinated contrast media (CM) are important considerations in coronary arteriography. A study was conducted in 24 patients to evaluate the acute electrolyte alterations in the coronary sinus during left coronary arteriography. During left coronary arteriography, coronary sinus blood was withdrawn for measurement of electrolytes. The CM used were diatrizoate, ioxaglate, iohexol, and iopamidol. The hematocrit was decreased moderately by all 4 CM used at 5 s and returned to the control level at 15 s. The level of ionized calcium was decreased by all CM at 5 s. Prolonged reduction of ionic calcium was observed with diatrizoate and ioxaglate at 15 s. The level of potassium was almost unchanged by diatrizoate and ioxaglate in spite of hemodilution, which may lead us to a hypothesis that potassium can be released from the intracellular spaces such as red blood cells and vascular endothelial cells. Thus the depression of left ventricular function might be caused not only by reduction of ionized calcium, but also by a relative increase in the level of serum potassium.
authors: Department of Radiology and the Cardiology, Kyoto City Hospital, Japan.
authors: K
authors: K
authors: Hayakawa
authors: M
authors: M
authors: Mitsumori
authors: H
authors: H
authors: Uwatoko
authors: T
authors: T
authors: Monji
authors: Y
authors: Y
authors: Okuno
authors: T
authors: T
authors: Torizuka
authors: Y
authors: Y
authors: Satoh
authors: F
authors: F
authors: Tanaka
authors: K
authors: K
authors: Kitamura
authors: T
authors: T
authors: Misaki
mesh_terms: D000328:Adult; D000368:Aged; D001769:Blood / Q000187:drug effects; D002118:Calcium / Q000097:blood; D003287:Contrast Media / Q000009:adverse effects*; D017023:Coronary Angiography / Q000009:adverse effects*; D003331:Coronary Vessels / Q000187:drug effects*; D004573:Electrolytes / Q000097:blood*; D005260:Female; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D011446:Prospective Studies; D012964:Sodium / Q000097:blood
chemical_list: D003287:Contrast Media; D004573:Electrolytes; D012964:Sodium; D011188:Potassium; D002118:Calcium