[Thermodynamic and spectroscopic study of complex formation of dipeptides with dimethyl sulfoxide in their aqueous solutions].
Peculiarities of intermolecular interactions in water-dimethylsulfoxide solutions of dipeptides-glycyl-glycine, beta-alanyl-glycine, beta-alanyl-beta-alanine, DL-alpha-alanyl-DL-alpha-alanine, DL-alpha-alanyl-DL-valine-were analysed on the basis of thermodynamic characteristics and data on IR-spectra. Dimethylsulfoxide additions were shown to cause destruction of peptide associates present in aqueous solutions due to the formation of stronger bonds "peptide-DMSO". The existence of complexes between dimethylsulfoxide and beta-alanyl-glycine, beta-alanyl-beta-alanine, DL-alpha-alanyl-DL-alpha-alanine was found. The mechanism of their formation was determined by the dipeptide structure.
Kulikov
O V
OV
Badelin
V G
VG
Krestov
G A
GA
D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D004151:Dipeptides / Q000737:chemistry*; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D013816:Thermodynamics; D014867:Water / Q000737:chemistry*
D004151:Dipeptides; D012996:Solutions; D014867:Water; D004121:Dimethyl Sulfoxide
Termodinamicheskoe i spektroskopicheskoe issledovanie kompleksoobrazovaniia dipeptidov s dimetilsul'foksidom v ikh vodnykh rastvorakh.