title: In vitro susceptibility of Actinobacillus pleuropneumoniae strains to 42 antimicrobial agents.
abstract: Minimal inhibitory concentration of 42 antimicrobial agents was determined against 57 field strains of Actinobacillus pleuropneumoniae isolated from pigs in Spain. Penicillins, aminoglycosides, and tetracyclines had irregular activity; ticarcillin, tobramycin, and doxycycline were the most active of each group, respectively. Macrolides, vancomycin, dapsone, and tiamulin, to which strains had high rate of resistance, were almost ineffective. Thiamphenicol, colistin, rifampin, fosfomycin, mupirocin, and metronidazole had good activity, with resistance ranging between 0 and 8.8%. Finally, cephalosporins (except cephalexin) and quinolones (especially ciprofloxacin, enrofloxacin, and sparfloxacin) were the most active antibiotics against A pleuropneumoniae.
authors: Unidad de Microbiología e Inmunología, Falcultad de Veterinaria, Universidad de León, Spain.
authors: C B
authors: CB
authors: Gutiérrez
authors: S
authors: S
authors: Píriz
authors: S
authors: S
authors: Vadillo
authors: E F
authors: EF
authors: Rodríguez Ferri
mesh_terms: D016977:Actinobacillus pleuropneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D018942:Macrolides; D008826:Microbial Sensitivity Tests; D013552:Swine
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides