title: Hepatic acylcoenzyme A:cholesterol acyltransferase activity is low in hamsters fed apples in addition to a standard diet.
abstract: The effect of consumption of apples as a supplement to a standard diet on hepatic acylcoenzyme A: cholesterol acyltransferase (ACAT) activity was investigated in adult golden hamsters (Mesocricetus auratus). The experimental diet was given for 2 months. IN response to the high-fruit intake, the level of cholesteryl esters was reduced in the liver, and hepatic ACAT activity, determined in vitro under various conditions of incubation, was lowered by about 30%. Moreover, plasma cholesterol was redistributed among the lipoproteins, with a decrease in the cholesterol transported in the ApoB-rich lipoproteins.
authors: Laboratoire des Régulations des Métabolismes et Nutrition, CNRS, Université Paul Sabatier, Toulouse, France.
authors: R
authors: R
authors: Sablé-Amplis
authors: R
authors: R
authors: Sicart
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000097:blood / Q000378:metabolism; D006224:Cricetinae; D005638:Fruit; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D008297:Male; D008647:Mesocricetus; D002785:Sterol O-Acyltransferase / Q000378:metabolism*
chemical_list: D002784:Cholesterol; D002785:Sterol O-Acyltransferase