Clonogenic cytotoxicity testing by microdrop encapsulation.
Cytotoxicity is defined as the in situ measurement of cellular function in response to a toxic substance. Cytotoxicity assays are widely used in drug screening and development research to minimize the number of compounds on which expensive mammalian animal model toxicology studies are performed.
Goguen
B
B
One Cell Systems, Inc., Cambridge, Massachusetts 02139.
Kedersha
N
N
D002448:Cell Adhesion; D003114:Colony-Forming Units Assay / Q000379:methods*; D003603:Cytotoxins / Q000633:toxicity*; D004129:Dimethylpolysiloxanes; D005434:Flow Cytometry; D005782:Gels; D012685:Sepharose; D014116:Toxicology / Q000379:methods*; D014407:Tumor Cells, Cultured
D003603:Cytotoxins; D004129:Dimethylpolysiloxanes; D005782:Gels; D012685:Sepharose