title: [Prevalence of HIV infection among stable female partners of seropositive men].
abstract: Prevalence of HIV transmission to female sexual partners of seropositive men is not known yet. In order to know the condition in Japan, 11 HIV-seropositive men (25-42 years old; mean +/- SD, 32.5 +/- 6.0) and their stable female partners (24-42 years old; mean +/- SD, 31.3 +/- 6.0) were analyzed. Seropositive men consisted of seven hemophiliacs including a hemophiliac with intravenous drug abuse, three men who acquired HIV infection through heterosexual contact, and a man with intravenous drug abuse. Six of them were asymptomatic carriers, two had AIDS-related complex, and three had AIDS. All of the female partners had no risk factors other than sexual contact with their stable, seropositive male partners, except one who used to inject intravenous drug. Four of 11 female partners (36%) were found to be infected with HIV. All of the male partners of infected females had AIDS or AIDS-related complex, and had CD4 counts fewer than 100 cells/microliters. Asymptomatic carriers and men with CD4 counts more than 200 cells/microliters did not transmit HIV to their partners: rate of transmission of HIV by symptomatic men was significantly higher than that by asymptomatic men (p < 0.01), and the rate by men with CD4 counts fewer than 100 cells/microliters was also significantly higher than that by men with larger CD4 counts (p < 0.01). HIV-p24 antigen was measured in 10 of 11 seropositive men. The antigen was positive in four men, and negative in six.(ABSTRACT TRUNCATED AT 250 WORDS)
authors: Department of Infectious Diseases and Applied Immunology, University of Tokyo.
authors: S
authors: S
authors: Kimura
authors: S
authors: S
authors: Oka
authors: K
authors: K
authors: Shimada
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000635:transmission; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000635:transmission*; D006801:Humans; D008297:Male; D012747:Sexual Partners; D013997:Time Factors