[Gastric adenocarcinoma with an endocrine component. Report of nine cases].
Nine gastric adenocarcinomas containing endocrine cells were retrospectively studied to evaluate anatomo-clinical and immunohistochemical features, and the out-come of the patients. These gastric tumors were bulky with frequently lymph node metastasis. The immunohistochemical analysis had shown that all tumors contain EC cells, two tumors D cells, one tumor PP cells, but neither G cells nor A cells were detected. Five-years survival rate of these gastric tumors was slightly but not significantly increased as compared to usual adenocarcinomas (45.5% vs 36.5%). However, one can raise the question of possible control of local hormonal secretions on tumoral growth, particularly the anti-trophic part of the somatostatin.
Lepidi
H
H
Service d'Anatomie Pathologique, Institut Paoli-Calmettes, Marseille.
Monges
G
G
Delpero
J R
JR
Houvenaeghel
G
G
Parc
P
P
Hassoun
J
J
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology*; D000368:Aged; D004702:Endocrine Glands / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology*; D015996:Survival Rate
Adénocarcinomes gastriques à composante endocrine. A propos de neuf cas.