[Primary treatment of acute promyelocytic leukemia using all-trans-retinoic acid].
We describe the medical history of a 68-year-old woman with acute promyelocytic leukaemia. As primary treatment she received all-trans retinoic acid. For the major part this treatment could be given on an outpatient basis. After 60 days there was a complete remission of the leukaemia with disappearance of the characteristic cytogenetic abnormality t(15;17)(q22;q21).
Leeksma
O C
OC
Academisch Medisch Centrum, afd. Hematologie, Amsterdam.
van Oers
M H
MH
van der Schoot
C E
CE
Goudsmit
R
R
von dem Borne
A E
AE
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001803:Blood Transfusion; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy* / Q000628:therapy; D017713:Platelet Transfusion; D012074:Remission Induction; D014212:Tretinoin / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D014212:Tretinoin
Primaire behandeling van acute promyelocytenleukemie met all-trans-retinoïnezuur.