New delta 8- and delta 8(14)-5 alpha,6 alpha-epoxysterols from the marine sponge Spongia officinalis.
Six new delta 8- and delta 8(14)-5 alpha,6 alpha-epoxysterols (1-6) have been isolated from a collection of the Mediterranean sponge Spongia officinalis. The structures of the new metabolites, isolated as diacetate derivatives, have been determined by spectral analyses and an x-ray diffraction experiment performed on the diacetyl derivative of 1.
Migliuolo
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Dipartimenti di Chimica Organica e Biologica, Università di Napoli, Italy.
Piccialli
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Sica
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Giordano
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D000818:Animals; D002775:Cholestadienols / Q000737:chemistry / Q000302:isolation & purification*; D002782:Cholestenes / Q000737:chemistry / Q000302:isolation & purification*; D003460:Crystallization; D004852:Epoxy Compounds / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D014961:X-Ray Diffraction
D002775:Cholestadienols; D002782:Cholestenes; D004852:Epoxy Compounds