title: A double-blind trial of the clinical effects of pulsed electromagnetic fields in osteoarthritis.
abstract: OBJECTIVE
  Further evaluation of pulsed electromagnetic fields (PEMF), which have been observed to produce numerous biological effects, and have been used to treat delayed union fractures for over a decade.
  
  
  METHODS
  In a pilot, double-blind randomized trial, 27 patients with osteoarthritis (OA), primarily of the knee, were treated with PEMF. Treatment consisted of 18 half-hour periods of exposure over about 1 month in a specially designed noncontact, air-coil device. Observations were made on 6 clinical variables at baseline, midpoint of therapy, end of treatment and one month later; 25 patients completed treatment.
  
  
  RESULTS
  An average improvement of 23-61% occurred in the clinical variables observed with active treatment, while 2 to 18% improvement was observed in these variables in placebo treated control patients. No toxicity was observed.
  
  
  CONCLUSIONS
  The decreased pain and improved functional performance of treated patients suggests that this configuration of PEMF has potential as an effective method of improving symptoms in patients with OA. This method warrants further clinical investigation.
authors: Department of Medicine (Rheumatology), Danbury Hospital, CT 06810.
authors: D H
authors: DH
authors: Trock
authors: A J
authors: AJ
authors: Bollet
authors: R H
authors: RH
authors: Dyer
authors: L P
authors: LP
authors: Fielding
authors: W K
authors: WK
authors: Miner
authors: R
authors: R
authors: Markoll
mesh_terms: D004311:Double-Blind Method; D004574:Electromagnetic Fields; D005260:Female; D006801:Humans; D010003:Osteoarthritis / Q000453:epidemiology / Q000628:therapy*; D010865:Pilot Projects; D013997:Time Factors