Minimum alveolar concentration of sevoflurane in elderly patients.
We have determined the minimum alveolar concentration (MAC) for sevoflurane in elderly patients (mean age 71.4 yr). MAC was found to be 1.48 (SEM 0.08)%, which is smaller than the values for children and adults. The magnitude of the change in MAC with age is similar to that for halothane and isoflurane. The calculated anesthetic ED95 for preventing 95% of patients from moving was 1.98%.
Nakajima
R
R
Department of Anesthesiology and Critical Care Medicine, Hamamatsu University School of Medicine, Japan.
Nakajima
Y
Y
Ikeda
K
K
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000777:Anesthetics / Q000032:analysis*; D004987:Ethers / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008738:Methyl Ethers; D008875:Middle Aged; D011650:Pulmonary Alveoli / Q000737:chemistry*; D000077149:Sevoflurane; D013990:Tidal Volume
D000777:Anesthetics; D004987:Ethers; D008738:Methyl Ethers; D000077149:Sevoflurane