title: Unmasking of latent hypoparathyroidism in a child with partial DiGeorge syndrome by ethylenediaminetetraacetic acid infusion.
abstract: DiGeorge syndrome is a rare congenital anomaly with a wide range of clinical manifestations. This syndrome is usually associated with hypocalcaemia resulting from primary hypoparathyroidism. We report here a case of an 8-year-old boy with partial DiGeorge syndrome who presented initially with neonatal hypocalcaemia, but was subsequently normocalcaemic. Latent hypoparathyroidism was unmasked by a diagnostic EDTA infusion resulting in hypocalcaemia without a parathyroid hormone response. We propose that EDTA infusions can be useful in the diagnosis of latent hypoparathyroidism in children.
authors: Division of Endocrinology and Metabolism, Tokyo Metropolitan Kiyose Children's Hospital, Japan.
authors: T
authors: T
authors: Hasegawa
authors: Y
authors: Y
authors: Hasegawa
authors: T
authors: T
authors: Yokoyama
authors: S
authors: S
authors: Koto
authors: S
authors: S
authors: Asamura
authors: Y
authors: Y
authors: Tsuchiya
mesh_terms: D002648:Child; D004062:DiGeorge Syndrome / Q000097:blood / Q000150:complications*; D004492:Edetic Acid; D006801:Humans; D007011:Hypoparathyroidism / Q000175:diagnosis* / Q000209:etiology; D008297:Male
chemical_list: D004492:Edetic Acid