Treatment failure of a single high dose of ivermectin for Mansonella perstans filariasis.
Infections with Mansonella perstans are common in certain parts of Africa and South America. There is no standard treatment at present. We evaluated the effect of a single high dose of ivermectin (600 micrograms/kg) on microfilaraemia in 7 consecutive patients. No decrease in microfilarial counts could be demonstrated after a follow-up period of 7-56 d.
Van den Enden
E
E
Institute for Tropical Medicine, Antwerp, Belgium.
Van Gompel
A
A
Van der Stuyft
P
P
Vervoort
T
T
Van den Ende
J
J
D000328:Adult; D000368:Aged; D000818:Animals; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008368:Mansonelliasis / Q000188:drug therapy*; D008842:Microfilariae; D008875:Middle Aged; D017211:Treatment Failure
D007559:Ivermectin