title: The effects of an artificial meniscus substitute in a knee joint with a resected anterior cruciate ligament. An experimental study in rabbits.
abstract: A Dacron meniscus prosthesis was substituted for the medial meniscus in an anterior cruciate ligament (ACL) resected rabbit knee. At three months, the joints were evaluated biomechanically, with gross and histologic inspection. In a paired comparison with the contralateral knee, differences between ACL resection with intact, incised, or resected medial menisci were evaluated. Knees with intact menisci and ligaments served as controls. Because of cartilage destruction, soft-tissue hypertrophy, and increased anterior laxity, joint stiffness was less than normal in all ACL-resected knees. Ingrowth and stable fixation, especially of the posterior horns of the prostheses and the incised menisci, were rare. Almost all normal menisci had ruptured in the same area. Anterior cruciate ligament resection led to severe osteoarthrosis in both compartments, regardless of initial meniscal treatment. Knees with prostheses had the same incidence and severity of osteoarthrosis as knees with meniscus resection. Anterior cruciate ligament resection alone induced excessive osteoarthrosis and synovitis and diminished the effects of different meniscal treatments three months earlier.
authors: Department of Orthopaedics, University Hospital, Linköping, Sweden.
authors: K
authors: K
authors: Sommerlath
authors: J
authors: J
authors: Gillquist
mesh_terms: D000818:Animals; D016118:Anterior Cruciate Ligament / Q000601:surgery*; D001696:Biomechanical Phenomena; D001706:Biopsy; D005069:Evaluation Studies as Topic; D005355:Fibrosis; D006984:Hypertrophy; D007719:Knee Joint; D007720:Knee Prosthesis; D008592:Menisci, Tibial / Q000601:surgery*; D010003:Osteoarthritis / Q000453:epidemiology* / Q000473:pathology / Q000503:physiopathology; D011183:Postoperative Complications / Q000453:epidemiology* / Q000473:pathology / Q000503:physiopathology; D011474:Prosthesis Design; D011817:Rabbits; D012720:Severity of Illness Index; D016474:Weight-Bearing