[Oro-esophageal candidiasis resistant to fluconazole in patients with AIDS].
BACKGROUND
Fluconazole-resistant Candida albicans has been seldom reported in the literature. in this study, two clinical cases of oro-esophageal candidosis resistant to this antifungal drug are described.


METHODS
Infection was confirmed by isolation of yeasts (culture of mouth swabs, oesophagoscopy and histology of biopsy specimens). In vitro antifungal susceptibility tests were performed with standard methods (NCCLS).


RESULTS
Clinical and microbiological fluconazole-resistant Candida albicans was isolated.


CONCLUSIONS
Causes of development of resistances are commented, and the role of immunodeficiency and the possibility of a Candida strain selection is discussed.
Diz
P
P
Facultad de Medicina y Odontología, Universidad de Santiago de Compostela, La Coruña.
Ocampo
A
A
Miralles
C
C
Otero
I
I
Iglesias
I
I
Martínez
C
C
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology; D000328:Adult; D002177:Candidiasis / Q000188:drug therapy* / Q000382:microbiology; D002180:Candidiasis, Oral / Q000188:drug therapy*; D004352:Drug Resistance, Microbial; D004941:Esophagitis / Q000188:drug therapy* / Q000382:microbiology; D015725:Fluconazole / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D012008:Recurrence
D015725:Fluconazole
Candidosis oroesofágica resistente al fluconazol en pacientes con SIDA.