[Botulinum toxin. A new therapeutic alternative in spastic dysphonia (laryngeal abductor dystonia)].
Laryngeal dystonia is a condition characterized by involuntary spasms of the laryngeal muscles. In most patients this involves the adductor laryngeal muscles (adductor laryngeal dystonia). Treatment with a variety of therapies, including speech therapy and pharmacotherapy, have led to minimal improvement. Injections of botulinum-toxin (Botox) bilaterally into the vocalis muscles is a new treatment for adductor laryngeal dystonia. Since May 1991 we have treated 23 patients with adductor laryngeal dystonia with botulinum-toxin. In 74% of the patients the voice improved within 24-72 hours, and effect lasted for 2-14 months (average four months). Most of the patients got a breathy voice and a mild sensation of dysphagia during the first week after the injection.
Loven
J O
JO
Ore-nese-halsavdelingen Rikshospitalet, Oslo.
Brøndbo
K
K
Ganes
T
T
D000328:Adult; D000368:Aged; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use*; D004421:Dystonia / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007821:Laryngeal Muscles / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D014832:Voice Disorders / Q000503:physiopathology / Q000628:therapy*
D001905:Botulinum Toxins
Botulinumtoksin. Et nytt behandlingsalternativ ved spastisk dysfoni (laryngeal adduktordystoni).