Preliminary experience with a modified Tenckhoff catheter for intraperitoneal chemotherapy.
This study reports our preliminary experience with a modified Tenckhoff catheter for intraperitoneal chemotherapy, primarily designed to be larger, longer, and have more perfusion holes. There were 137 catheters implanted in 125 ovarian cancer patients from June 1988 to December 1990, among which 116 were actually used for intraperitoneal chemotherapy. A total of 559 cycles of intraperitoneal chemotherapy was given with a range of 1 to 16 uses per catheter. There were seven infections (6.0%), four inflow obstructions (3.4%), three bowel perforations (2.6%), and one leakage (0.8%). Among patients with catheter infection, three had delayed bowel perforation. Although the incidence of inflow obstruction was reduced from 5.5 to 3.4%, the improvement did not reach statistical significance. The frequency of delayed bowel perforation and infection were similar to the literature experience of other catheters. An unused catheter should be removed to avoid this serious complication. Further study is needed to evaluate fully the performance of this catheter system.
Nguyen
H N
HN
Division of Gynecologic Oncology, University of Miami School of Medicine, FL 33101.
Averette
H E
HE
Wyble
L
L
Sevin
B U
BU
Donato
D
D
Penalver
M
M
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002408:Catheters, Indwelling; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007274:Injections, Intraperitoneal / Q000295:instrumentation*; D010051:Ovarian Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents