Nerve-like myoid differentiation in sclerosing adenosis of breast. A diagnostic pitfall.
A surgically excised lesion from the breast of a 33 year old woman showed apart from cystic disease sclerosing adenosis with distinct myoid differentiation. The myoid bundles were wrapped around original ductules producing a misleading picture which simulated tangentially cut nerves, infiltrated by tumour glands. Immunohistochemically, actin positivity and S-100 protein negativity confirmed the nature of the lesion as sclerosing adenosis.
Sikl's Department of Pathology, Medical Faculty Charles University, Pilsen, Czech Republic.
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Michal
D000328:Adult; D001940:Breast / Q000294:innervation; D001943:Breast Neoplasms / Q000473:pathology*; D002454:Cell Differentiation; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry