High-grade pleomorphic T cell lymphoma with restricted involvement of skin and bone marrow.
Pleomorphic T cell lymphoma of the medium to large cell type expressing CD30 antigen is a most aggressive peripheral T cell lymphoma. Currently, there is no satisfactory treatment available for this neoplasm. We report the case of a woman with prominent skin and bone marrow involvement without detectable lymph node localization. This unusual presentation of disease responded well to polychemotherapy combined with autologous bone marrow transplantation.
Service de Dermatologie, CHU du Sart Tilman, Liège, Belgique.
M S
MS
Gautier
G E
GE
Piérard
F
F
Andrien
J F
JF
Hermanns
C
C
Piérard-Franchimont
G
G
Fillet
C M
CM
Lapière
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*