Granulocyte elastase alpha 1-proteinase inhibitor complex measurement in very low birthweight infants with severe intraventricular hemorrhage.
We investigated the relationship between the levels of granulocyte elastase alpha 1-proteinase inhibitor complex (E-alpha 1-PI) in plasma and severe intraventricular hemorrhage (IVH) in very low birthweight infants. The concentrations of E-alpha 1-PI and the ratio of the concentrations of E-alpha 1-PI to polymorphonuclear leucocyte counts within 24 h of birth in infants with severe IVH were significantly higher compared with those in infants without severe IVH. E-alpha 1-PI seems to be a useful indicator of IVH.
Department of Pediatrics, Saitama Medical Center, Saitama Medical School, Japan.
J
J
Takasaki
K
K
Kamiya
Y
Y
Ogawa
T
T
Tanaka
N
N
Koyama
D002543:Cerebral Hemorrhage / Q000097:blood* / Q000145:classification; D002552:Cerebral Ventricles; D004797:Enzyme-Linked Immunosorbent Assay; D005069:Evaluation Studies as Topic; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007958:Leukocyte Count; D019272:Leukocyte Elastase; D009504:Neutrophils; D010196:Pancreatic Elastase / Q000032:analysis*; D011237:Predictive Value of Tests; D011379:Prognosis; D012720:Severity of Illness Index; D000515:alpha 1-Antitrypsin / Q000032:analysis*
D000515:alpha 1-Antitrypsin; C037741:alpha 1-antitrypsin-leukocyte elastase complex; D010196:Pancreatic Elastase; D019272:Leukocyte Elastase