The lupus anticoagulant and pregnancy.
The lupus anticoagulant has been understood for more than 40 years. However, reports of obstetric cases, although available, are not frequent. The author reviews the literature on this subject, including current recommendations on managing the problem in pregnancy. He reports a single case that involved a spontaneous abortion and a subsequent pregnancy in the same person. The second pregnancy during which the patient received prednisone and aspirin therapy, had a successful outcome.
Department of Family Medicine, Marshfield Clinic-Mercer Center, Wis.
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Olson
D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood* / Q000188:drug therapy
D016682:Lupus Coagulation Inhibitor; D001241:Aspirin; D011241:Prednisone