Correction of vitamin E deficiency with fat-soluble versus water-miscible preparations of vitamin E in patients with cystic fibrosis.
Of 27 patients with cystic fibrosis, 17 had levels of alpha-tocopherol more than 2 SD below the mean. Patients were randomly given either a water-miscible form of vitamin E or a fat-soluble form for 6 months. Either form was effective in achieving normal serum levels; the fat-soluble supplement has a significant cost advantage.
Department of Pediatrics, University of Michigan Medical Center, Ann Arbor 48109-0718.
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O'Leary
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D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D016896:Treatment Outcome; D014810:Vitamin E / Q000008:administration & dosage / Q000627:therapeutic use*; D014811:Vitamin E Deficiency / Q000188:drug therapy* / Q000209:etiology
D014810:Vitamin E