A new perspective on muscle contraction.
Recent experimental findings suggest that the myosin cross-bridge theory may no longer be adequate to account for certain basic facts concerning muscle contraction. A newly-proposed mechanism based on length changes in actin filaments might be the basis for a simpler explanation for how the free energy of ATP hydrolysis can be transduced into work by muscle fibers.
Schutt
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CE
Henry H. Hoyt Laboratory, Princeton University, NJ 08544.
Lindberg
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D000199:Actins / Q000502:physiology; D000251:Adenosine Triphosphatases / Q000378:metabolism; D008954:Models, Biological; D009119:Muscle Contraction / Q000502:physiology*; D009132:Muscles / Q000502:physiology
D000199:Actins; D000251:Adenosine Triphosphatases