Kinetic model of parasite development and of the host microelement content under combined drug treatment.
The content of nine microelements has been investigated in a parasite-host system by nondestructive neutron activation analysis. A mathematical model has been proposed for the development of Ascaridia galli in the "Leghorn" chicks intestines and for the microelement content dynamics under combined treatment with antiparasite agent and microelements. An analytical solution of the system of nonlinear differential equations has been obtained for the case of simple invasion. The model explains well the experimentally observed process of the change in the microelement content. The recovery constant has been introduced for the damaged by the helminthosis tissue and its value has been determined.
Damyanova
A
A
Institute of Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Sofia.
Teodorova
S
S
Gabrashanska
M
M
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D001197:Ascaridia / Q000254:growth & development*; D001198:Ascaridiasis / Q000188:drug therapy / Q000378:metabolism / Q000469:parasitology / Q000662:veterinary*; D002645:Chickens / Q000378:metabolism* / Q000469:parasitology*; D004602:Elements; D006790:Host-Parasite Interactions; D008954:Models, Biological; D011201:Poultry Diseases / Q000188:drug therapy / Q000378:metabolism / Q000469:parasitology*
D000871:Anthelmintics; D004602:Elements