[The ultrastructural and cytointerferometric changes in blood cells induced by endotoxin action].
The results of ultrastructural and cytointerferometric changes of different blood cells in the main target-organ microcirculation are present in the dynamics of endotoxin shock. It is established that the development of endotoxin shock is accompanied by a decrease in dry mass and content of dense substance in red blood cells and leucocytes. Ultrastructural alterations of blood cells have a stable enough character and may be the action of humoral mediator systems or due to direct effects of lipopolysaccharide. Ultrastructural and cytointerferometric changes are discussed in the context of possible receptor-ligand interrelations.
N G
NG
Kharlanova
E A
EA
Bardakhch'ian
Iu M
IuM
Lomov
D000818:Animals; D001773:Blood Cells / Q000187:drug effects* / Q000648:ultrastructure*; D004731:Endotoxins / Q000633:toxicity*; D004926:Escherichia coli; D008297:Male; D008854:Microscopy, Electron; D008857:Microscopy, Interference; D051381:Rats; D013997:Time Factors; D014115:Toxemia / Q000097:blood
D004731:Endotoxins
Ul'trastrukturnye i tsitointerferometricheskie izmeneniia nekotorykh kletok krovi, vyzvannye deĭstviem éndotoksina.