Primary osteoporosis. Methods to combat bone loss that accompanies aging.
Osteoporosis is a major public health problem in the United States. The key to its management is prevention by ensuring adequate amounts of calcium, vitamin D, and protein and exercise throughout life. When a significant amount of bone mass has been lost, therapeutic interventions are aimed at preventing further loss with use of antiresorptive agents (ie, estrogen, progestin, calcitonin, and bisphosphonates). Use of pharmacologic agents that stimulate bone formation is still in experimental stages. Research efforts focusing on prevention, diagnosis, and treatment of osteoporosis are in progress and should provide improved strategies in the future.
Department of Medicine, University of Missouri-Columbia School of Medicine 65212.
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Allen
D000328:Adult; D000367:Age Factors; D000368:Aged; D015519:Bone Density; D016723:Bone Remodeling; D001862:Bone Resorption; D002116:Calcitonin / Q000627:therapeutic use; D002118:Calcium / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D015984:Causality; D015914:Estrogen Replacement Therapy; D012968:Etidronic Acid / Q000627:therapeutic use; D015444:Exercise; D005194:Family Practice; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009751:Nutritional Requirements; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D011322:Primary Prevention; D012907:Smoking / Q000009:adverse effects
D002116:Calcitonin; D012968:Etidronic Acid; D002118:Calcium