HLA class II alleles in juvenile dermatomyositis.
HLA class II alleles were investigated in 27 Czech patients (11 females and 16 males) with juvenile dermatomyositis. The immunogenetic investigation comprised determination of DRB1, DRB3, DRB5, DQA1, DQB1, and DPB1 alleles. Their prevalence was compared with that found in healthy Czech controls. No allele was found significantly more frequently in patients than in controls.
Pediatric Rheumatology Unit, Institute of Rheumatology, Prague, Czech Republic.
P
P
Vavrincová
S
S
Havelka
M
M
Cerna
P
P
Stastny
D000293:Adolescent; D000483:Alleles; D002648:Child; D002675:Child, Preschool; D003882:Dermatomyositis / Q000235:genetics / Q000276:immunology*; D005260:Female; D006682:HLA-DP Antigens / Q000032:analysis / Q000235:genetics; D059868:HLA-DP beta-Chains; D006683:HLA-DQ Antigens / Q000032:analysis / Q000235:genetics; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; D006684:HLA-DR Antigens / Q000032:analysis / Q000235:genetics; D059811:HLA-DRB1 Chains; D059826:HLA-DRB3 Chains; D059847:HLA-DRB5 Chains; D000949:Histocompatibility Antigens Class II / Q000032:analysis / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male
D006682:HLA-DP Antigens; D059868:HLA-DP beta-Chains; C071170:HLA-DPB1 antigen; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; C069050:HLA-DQA1 antigen; C069051:HLA-DQB1 antigen; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D059826:HLA-DRB3 Chains; D059847:HLA-DRB5 Chains; D000949:Histocompatibility Antigens Class II