Long-term evolution of chronic delta hepatitis in children.
Twenty-three children, aged 3 to 15 years, with chronic delta hepatitis have been followed for 5 to 12 years to evaluate long-term outcome. Although 83% of patients had chronic active hepatitis when first seen, with cirrhosis in 26%, the clinical and biochemical features of the disease remained reasonably stable during observation; liver histologic findings, obtained in 14 patients, worsened in only two.
Clinica Medica 2, Department of Infectious Diseases, Padua, Italy.
F
F
Bortolotti
V
V
Di Marco
P
P
Vajro
C
C
Crivellaro
L
L
Zancan
G
G
Nebbia
C
C
Barbera
M
M
Tedesco
A
A
Craxi
M
M
Rizzetto
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D003699:Hepatitis D / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D006521:Hepatitis, Chronic / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D008099:Liver / Q000473:pathology; D008297:Male; D011994:Recombinant Proteins; D012074:Remission Induction; D012075:Remission, Spontaneous; D013997:Time Factors
D007370:Interferon Type I; D011994:Recombinant Proteins