[Extrapulmonary and disseminated pneumocystosis in HIV infection].
Three cases of extrapulmonary disseminated Pneumocystis carinii infection are reported. All 3 patients had HIV infection with less than 50 CD4 lymphocytes per cubic millimeter and were having aerosols of pentamidine as prophylactic treatment of pneumocystosis. P. carinii may invade numerous organs and in particular the liver, spleen and bone marrow. Extrapulmonary lesions, often pan-symptomatic, are to be feared in deeply immunodepressed patients receiving prophylactic aerosols of pentamidine. Infection of the choroid can be detected by systematic ophthalmoscopy. An early diagnosis raises hopes of a good, if temporary, response to treatment.
Service des Maladies infectieuses, parasitaires et tropicales-Réanimation médicale, CHRU, Caen.
C
C
Bazin
P
P
Hazera
A
A
Greder
P
P
Cren
B
B
Lechevalier
E
E
Gallet
P
P
Charbonneau
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D001855:Bone Marrow Diseases / Q000150:complications / Q000382:microbiology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology*; D008297:Male; D010419:Pentamidine / Q000627:therapeutic use; D016720:Pneumocystis Infections / Q000150:complications / Q000188:drug therapy; D011020:Pneumonia, Pneumocystis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D013158:Splenic Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
D010419:Pentamidine
Pneumocystoses extrapulmonaires et disséminées au cours de l'infection par le VIH.