Combined oesophageal adenocarcinoma and carcinoid in Barrett's oesophagitis: potential role of enterochromaffin-like cells in oesophageal malignancy.
A case of combined adenocarcinoma and carcinoid tumour which occurred in a patient with a Barrett's oesophagus is presented. Its significance is discussed in relation to the potential role of enterochromaffin-like cells in the development of oesophageal malignancy, and the possibility is raised that long term treatment with omeprazole, commonly used in this condition, could promote this.
Cary
N R
NR
Department of Pathology, Papworth Hospital, Everard, Cambridge.
Barron
D J
DJ
McGoldrick
J P
JP
Wells
F C
FC
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D001471:Barrett Esophagus / Q000150:complications / Q000473:pathology*; D001706:Biopsy; D002276:Carcinoid Tumor / Q000150:complications / Q000473:pathology; D004759:Enterochromaffin Cells / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged