Rhabdomyolysis associated with malaria tertiana in a patient with myoadenylate deaminase deficiency.
A male patient presented with malaria tertiana due to Plasmodium vivax. He developed a severe attack of rhabdomyolysis with acute renal failure. The patient was treated successfully with chloroquine medication. After complete recovery further muscle study revealed a deficiency of myoadenyl deaminase (MAD). The infection with P. vivax probably has been the triggering factor in the process of muscle necrosis, because the patient also had MAD deficiency.
Poels
P J
PJ
Institute of Neurology, Nijmegen University Hospital, The Netherlands.
Dolmans
W M
WM
Gabreëls
F J
FJ
D000659:AMP Deaminase / Q000172:deficiency*; D058186:Acute Kidney Injury / Q000150:complications; D000328:Adult; D002738:Chloroquine / Q000627:therapeutic use; D006801:Humans; D016780:Malaria, Vivax / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D012206:Rhabdomyolysis / Q000175:diagnosis / Q000209:etiology*
D002738:Chloroquine; D000659:AMP Deaminase