Engineered bacterial receptors in immunology.
Gram-positive surface receptors, such as staphylococcal protein A ans streptococcal protein G, have been genetically engineered for many applications in the field of immunology, including detection antigens, affinity purification of fusion proteins and display of heterologous epitopes on the surface of bacterial cells.
Ståhl
S
S
Department of Biochemistry and Biotechnology, Royal Institute of Technology, Stockholm, Sweden.
Nygren
P A
PA
Sjölander
A
A
Uhlén
M
M
D000941:Antigens / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D001426:Bacterial Proteins / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006094:Gram-Positive Bacteria / Q000235:genetics / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000302:isolation & purification / Q000378:metabolism; D007163:Immunosorbent Techniques; D015202:Protein Engineering; D011506:Proteins / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification / Q000378:metabolism; D013205:Staphylococcal Protein A / Q000235:genetics / Q000276:immunology / Q000378:metabolism
D000941:Antigens; D001426:Bacterial Proteins; C034284:IgG Fc-binding protein, Streptococcus; D007136:Immunoglobulins; D011506:Proteins; D011993:Recombinant Fusion Proteins; D013205:Staphylococcal Protein A