Amino-terminal sequence analysis of the Coccidioides immitis chitinase/immunodiffusion-complement fixation protein.
A chitinase isolated from Coccidioides immitis was subjected to amino-terminal protein sequence analysis. The resulting 18-amino-acid sequence was compared with the previously reported amino acid sequence of coccidioidal immunodiffusion-complement fixation (IDCF) antigen. From the homology of the two sequences, the results support the identification of the IDCF antigen with a chitinase.
Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis 95616.
S M
SM
Johnson
C R
CR
Zimmermann
D
D
Pappagianis
D000595:Amino Acid Sequence; D000946:Antigens, Fungal / Q000737:chemistry*; D002688:Chitinases / Q000737:chemistry*; D003045:Coccidioides / Q000276:immunology*; D003168:Complement Fixation Tests; D005779:Immunodiffusion; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid
D000946:Antigens, Fungal; D002688:Chitinases