The comprehensive assessment of health status in survivors of childhood cancer: application to high-risk acute lymphoblastic leukaemia.
The health status of 69 survivors of high-risk acute lymphoblastic leukaemia (ALL) is assessed using a multi-attribute classification system. Seven attributes are included: sensation, mobility, emotion, cognition, self-care, pain and fertility. Three to five levels of functioning are defined for each attribute. Comprehensive health states are described as a specific combination of seven attribute levels. The system captures combinations of sequelae. The system provides a compact but comprehensive tool for long term follow up of survivors of childhood cancer. The results underscore the cognitive and emotional burdens of morbidity affecting survivors of high-risk ALL.
Feeny
D
D
Department of Clinical Epidemiology and Biostatistics, McMaster University, Ontario, Canada.
Leiper
A
A
Barr
R D
RD
Furlong
W
W
Torrance
G W
GW
Rosenbaum
P
P
Weitzman
S
S
D003072:Cognition Disorders / Q000209:etiology; D005260:Female; D006801:Humans; D007246:Infertility / Q000209:etiology; D008297:Male; D017063:Outcome Assessment, Health Care; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000503:physiopathology*; D015996:Survival Rate