Rhabdomyolysis associated with malaria tertiana in a patient with myoadenylate deaminase deficiency.
A male patient presented with malaria tertiana due to Plasmodium vivax. He developed a severe attack of rhabdomyolysis with acute renal failure. The patient was treated successfully with chloroquine medication. After complete recovery further muscle study revealed a deficiency of myoadenyl deaminase (MAD). The infection with P. vivax probably has been the triggering factor in the process of muscle necrosis, because the patient also had MAD deficiency.
Institute of Neurology, Nijmegen University Hospital, The Netherlands.
P J
PJ
Poels
W M
WM
Dolmans
F J
FJ
Gabreëls
D000659:AMP Deaminase / Q000172:deficiency*; D058186:Acute Kidney Injury / Q000150:complications; D000328:Adult; D002738:Chloroquine / Q000627:therapeutic use; D006801:Humans; D016780:Malaria, Vivax / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D012206:Rhabdomyolysis / Q000175:diagnosis / Q000209:etiology*
D002738:Chloroquine; D000659:AMP Deaminase