Localized expression of the H-ras proto-oncogene during Ilyanassa development.
We have immunostained Ilyanassa embryos with an antibody to the ras protein and shown that the ras gene (1) is not expressed from early cleavage through the gastrula stage, but (2) is expressed during organogenesis by both normal and lobeless embryos, (3) that the ras protein is first synthesized from the third day of development in the normal embryo and from the fifth day of development in the lobeless embryo, and (4) that the expression of the ras protein is localized in mesodermal lineages of both normal and lobeless embryos.
Department of Biology, City University of New York, Brooklyn College 11210.
K
K
Yan
J R
JR
Collier
D000818:Animals; D002970:Cleavage Stage, Ovum / Q000737:chemistry; D005775:Gastrula / Q000737:chemistry; D005786:Gene Expression Regulation; D011905:Genes, ras; D008648:Mesoderm / Q000378:metabolism*; D009024:Morphogenesis; D009154:Mutation; D016283:Proto-Oncogene Proteins p21(ras) / Q000032:analysis* / Q000235:genetics; D012908:Snails / Q000196:embryology* / Q000235:genetics
D016283:Proto-Oncogene Proteins p21(ras)