[Antiphospholipid antibodies and cerebral ischemic infarction in a 6-year-old boy].
Lupus anticoagulant activity and anti-phospholipid antibodies (aPL) were found in a six-year-old child with cerebral ischemic infarction in the absence of any underlying disease. The association of these antibodies with thrombosis has been well documented in adult patients. In view of our observation, we believe that aPL may also be involved in the pathogenesis of arterial thrombotic events in childhood, and aPL should be systematically searched in these cases.
Forastiero
R R
RR
Sección Hemostasia y Trombosis, Hospital de Clínicas, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Falcón
C
C
Rodrigué
S
S
Kordich
L C
LC
Carreras
L O
LO
D017152:Antibodies, Antiphospholipid / Q000097:blood*; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications*; D001780:Blood Coagulation Tests; D002545:Brain Ischemia / Q000276:immunology*; D002544:Cerebral Infarction / Q000276:immunology*; D002648:Child; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D008297:Male; D010716:Phosphatidylinositols / Q000276:immunology
D017152:Antibodies, Antiphospholipid; D016682:Lupus Coagulation Inhibitor; D010716:Phosphatidylinositols
Anticuerpos antifosfolípidos e infarto isquémico cerebral en un niño de seis años.