Similarity of DNA fingerprints due to chance and relatedness.
Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance and relatedness. From these results, the degree of similarity due to relatedness alone may be calculated.
Li
C C
CC
Department of Human Genetics, Graduate School of Public Health, University of Pittsburg, Pa. 15261.
Weeks
D E
DE
Chakravarti
A
A
D000483:Alleles; D016172:DNA Fingerprinting; D005190:Family; D006801:Humans; D011336:Probability