Nonsteroidal anti-inflammatory agents in the management of canine allergic pruritus.
Pruritus associated with allergic skin diseases is an important reason for consultation in canine medicine. The pathophysiology of pruritus is poorly understood in the dog, but histamine, leukotrienes, and prostaglandins appear to be important mediators. The medical management of allergic pruritus in dogs with nonsteroidal anti-inflammatory agents is discussed. Antihistamines, tricyclic antidepressants, and omega-3/omega-6 fatty acid-containing products are often useful, either as single agents, in combinations, or for reducing glucocorticoid requirements.
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853.
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Scott
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Miller
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D006967:Hypersensitivity / Q000188:drug therapy / Q000662:veterinary*; D011537:Pruritus / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D012871:Skin Diseases / Q000188:drug therapy / Q000662:veterinary*
D000894:Anti-Inflammatory Agents, Non-Steroidal