Per-urethral transvesical first-trimester amniocentesis.
Early amniocentesis (before 13 weeks' gestation) using a per-urethral transvesical route is studied. Eight samples were obtained in eight patients scheduled for elective termination of pregnancy. The volume of amniotic fluid averaged 12.5 +/- 7.8 ml. Culture was successful in all samples. In one case, culture was achieved with only 2 ml of amniotic fluid. The amniotic fluid can be easily obtained via the per-urethral transvesical route. We conclude that early per-urethral amniocentesis before 13 weeks amenorrhea may be an alternative to the transabdominal route. A clinical trial should be carried out in order to evaluate both techniques.
Service de Gynécologie-Obstétrique, Hopital Antoine Béclère, Clamart, France.
R
R
Frydman
J C
JC
Pons
E
E
Borghi
J
J
Selva
F
F
Olivennes
F
F
O'Donovan
H
H
Fernandez
M
M
Le Lorc'h
D000649:Amniocentesis / Q000379:methods*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D014521:Urethra; D001743:Urinary Bladder