[Human parvovirus B19-induced aplastic crisis in an elderly man with intestinal hemorrhage].
An elderly man with an intestinal hemorrhage from bowel diverticulosis developed human parvovirus B19-induced aplastic crisis. A 71-year-old man noticed occasional tarry stools and at the same time showed fever, arthralgia and severe anemia. Blood counts revealed Hgb 5.3g/dl, reticulocytes 0%, and WBC 1,900/microliters. Bone marrow examination showed hypocellular marrow with rare erythroid precursors (4.8%). A few giant proerythroblasts were found in the bone marrow smears. A diagnosis of parvovirus B19 infection was made because of detection of B19-specific IgM and IgG antibodies. Parvovirus B19 infection should be carefully checked for in patients with hemorrhage as well as those with hemolysis.
Division of Hematology, University of Tsukuba.
M
M
Kamoshita
K
K
Ohtani
Y
Y
Hasegawa
Y
Y
Satoh
H
H
Kozima
A
A
Shibuya
H
H
Ninomiya
T
T
Nagasawa
Y
Y
Matsunaga
T
T
Abe
D000208:Acute Disease; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D004241:Diverticulum, Colon / Q000150:complications; D016731:Erythema Infectiosum / Q000150:complications*; D006471:Gastrointestinal Hemorrhage / Q000150:complications*; D006801:Humans; D008297:Male; D016732:Parvovirus B19, Human; D012010:Red-Cell Aplasia, Pure / Q000209:etiology* / Q000473:pathology