The cerebrospinal fluid from patients with prolactinoma promotes neurite growth of sensory neurones.
The cerebrospinal fluid (CSF) of patients with hypophysis adenomas was used to investigate its effect on organotypic cultures of dorsal root ganglia (DRG) of 10-11 day old chick embryo. Only the CSF from patients with prolactinoma showed a neurite-stimulating effect compared with other hypophysis adenomas.
I.P. Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg.
G N
GN
Akoev
K S
KS
Babu
N I
NI
Chalisova
M I
MI
Ludino
D000818:Animals; D002555:Cerebrospinal Fluid / Q000502:physiology; D002642:Chick Embryo; D005727:Ganglia, Spinal / Q000502:physiology*; D006801:Humans; D016501:Neurites / Q000502:physiology*; D009475:Neurons, Afferent / Q000648:ultrastructure*; D009924:Organ Culture Techniques; D010911:Pituitary Neoplasms / Q000134:cerebrospinal fluid*; D015175:Prolactinoma / Q000134:cerebrospinal fluid*