Predictive value of neurological abnormalities in HIV 1 patients in the early stages of the infection.
A longitudinal clinical neurological and electrophysiological follow-up study was carried out on 31 HIV1 seropositive outpatients in the asymptomatic or LAS stages of the infection (CDC II-III). The results of clinical examination and multimodal evoked potentials (EP) recording showed a high percentage of abnormalities (42% and 39% of cases respectively); in a statistically significant number of subjects these abnormalities were predictive of subsequent immunological deterioration, thus demonstrating the close relationship between neurological and immunological functions in HIV1 infection.
Tilia
G
G
Istituto di Clinica delle Malattie Nervose e Mentali, Università La Sapienza, Roma.
Spadaro
M
M
Soldati
G
G
Pinter
E
E
Morocutti
C
C
D000328:Adult; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006679:HIV Seropositivity / Q000276:immunology / Q000503:physiopathology*; D015497:HIV-1; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D011237:Predictive Value of Tests; D013997:Time Factors