Value of transrectal prostate ultrasonography pre-transurethral prostatectomy in screening for occult prostate carcinoma.
A total of 311 patients who underwent consecutive transurethral resection of prostate (TURP) for obstructive voiding symptoms were reviewed. All patients had benign prostate glands by digital rectal examination. Results of preoperative ultrasound screening of the prostate in 65 of 311 patients showed 41 with nonmalignant prostate, but pathologic examination showed cancer in 11 and benign hyperplasia in 30. Of seven ultrasounds interpreted as suspicious for cancer, pathologic examination revealed benign hyperplasia in all seven. Of 17 patients with ultrasound interpretations consistent with prostate cancer, 14 had transrectal ultrasound-guided prostate biopsies prior to TURP. Biopsy specimens revealed benign hyperplasia without carcinoma in all 14 patients. Two of 17 patients refused biopsies, and 1 underwent TURP without biopsy for urinary retention and did have cancer. Sensitivity of prostate ultrasound in evaluation of occult prostate carcinoma in this group of patients was 8.3 percent and specificity was 56.6 percent. Our results indicate that transrectal prostate ultrasound performed on men with obstructive voiding symptoms and benign glands as evidenced by digital rectal palpation has little value in predicting the presence or absence of occult prostate cancer.
Department of Urology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
M B
MB
Chancellor
C A
CA
VanAppledorn
D000368:Aged; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011468:Prostatectomy; D011469:Prostatic Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D012007:Rectum; D012189:Retrospective Studies; D014463:Ultrasonography / Q000379:methods