[The action of gamma irradiation on the luminol-dependent chemiluminescence of activated thymocytes].
The method of luminol-dependent chemiluminescence was used to study the affect of gamma radiation on activation of cells of thymus and bursa of Fabricius upon their adhesion on kapron. Thymocyte activation by adhesion on glass or kapron provoked chemiluminescence which was connected with the development in cells of active oxygen forms. The chemiluminescence amplitude was shown to increase with adhesion of thymocytes exposed to 1-5 Gy radiation and to decrease after a dose of 10 Gy. In cells of bursa of Fabricius, the analogous response to activation or irradiation was not observed.
Institute of Experimental Biology, Academy of Sciences of Estonia, Tallinn.
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Kööp
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Varjend
D000818:Animals; D002060:Bursa of Fabricius / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D002478:Cells, Cultured / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D002645:Chickens; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects* / Q000528:radiation effects*; D013601:T-Lymphocytes / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors
D008165:Luminol
Deĭstvie gamma-oblucheniia na liuminolzavisimuiu khemiliuminestsentsiiu aktivirovannykh timotsitov.