Efficacy of corticosteroids in reversing regression after myopic photorefractive keratectomy.
Topical corticosteroids are given commonly after photorefractive keratectomy (PRK). We present six eyes treated for correction of myopia ranging between -6.00 and -8.00 D, to whom corticosteroid drops were given and then suspended. Each eye had an increase in myopia with a mean of 2.00 D (range 1.00 to 3.50 D). All were then treated with topical dexamethasone (0.1%) four times per day for at least 15 days, and all showed decreases in myopia with partial or complete recovery of the intended correction (mean: 1.625 D; range 1.00 to 3.50 D). All of these refractive variations were documented by corneal topography. In one eye, refractive and topographic variations were detected by 3 days after corticosteroid treatment was initiated and they increased for 15 days. We believe corticosteroids can modulate refractive changes after PRK.
Carones
F
F
Department of Ophthalmology, University of Milan, Scientific Institute San Raffaele Hospital, Italy.
Brancato
R
R
Venturi
E
E
Scialdone
A
A
Bertuzzi
A
A
Tavola
A
A
D000328:Adult; D003315:Cornea / Q000601:surgery*; D003319:Corneal Stroma / Q000187:drug effects; D003907:Dexamethasone / Q000008:administration & dosage*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D053685:Laser Therapy; D009216:Myopia / Q000503:physiopathology / Q000517:prevention & control* / Q000601:surgery*; D009883:Ophthalmic Solutions; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control*; D012029:Refraction, Ocular; D014792:Visual Acuity
D009883:Ophthalmic Solutions; D003907:Dexamethasone