[Mononeuritis multiplex as initial manifestation of systemic granulomatosis].
We report two young patients with a painful and rapidly progressive polyneuropathy of the mononeuritis multiplex type confiding them to bed. Extensive investigations led to the diagnosis of a granulomatosis in both: Churg-Strauss allergic granulomatosis in one and Wegener's granulomatosis in the other. The importance and frequency of peripheral nervous system manifestations in the presenting clinical pattern of a systemic granulomatosis and vasculitis are discussed. Their proper recognition with regard to available effective therapeutic measures is stressed.
Neurologische Universitätsklinik, Inselspital, Bern.
M
M
Sturzenegger
A
A
Stratmann
P
P
Wyss
D000328:Adult; D001369:Axons / Q000502:physiology; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D009132:Muscles / Q000294:innervation; D009460:Neurologic Examination; D010525:Peripheral Nerves / Q000503:physiopathology; D011115:Polyneuropathies / Q000209:etiology* / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology
Mononeuritis multiplex als Erstmanifestation einer systemischen Granulomatose.