Physiologic and behavioral responses of children receiving intermittent intravenous morphine following orthopaedic surgery.
The purpose of this study was to describe the physiologic and behavioral responses of children receiving intermittent intravenous morphine following orthopaedic surgery. The nonrandomized sample was made up of 29 children between the ages of 6 months and 11 years. Subjects received morphine IV push over 5 minutes (0.1 mg/kg body weight) every 3-4 hours prn. Heart rate, respiratory rate, transcutaneous CO2 and oxygen saturation were collected prior to administration and then at 5-minute intervals for a total of 25 minutes. Pain cue behaviors were assessed prior to morphine and at 25 minutes after intravenous injection, the time of peak analgesia. Subjects received a total of 199 doses of morphine. Physiologic data were analyzed using repeated measures of variance with Waller-Duncan multiple comparison procedures. The results of this study support the safe and effective use of intravenous morphine in children 6 months to 11 years following orthopaedic surgery.
Trentadue
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NC
Bollig
A
A
D002648:Child; D002675:Child, Preschool; D015400:Clinical Nursing Research; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D008991:Monitoring, Physiologic; D009020:Morphine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D009730:Nursing Assessment; D016530:Orthopedic Nursing; D010149:Postoperative Pain / Q000188:drug therapy* / Q000451:nursing / Q000503:physiopathology
D009020:Morphine