[Toxoplasmosis in pregnancy. Diagnosis and new therapeutic possibilities].
Congenital toxoplasmosis results from contamination of the foetus by Toxoplasma gondii during pregnancy. It is a frequent and severe condition calling for close surveillance of mothers at risk. During the last few years, numerous advances have been made in the diagnosis and treatment of toxoplasmosis. Its diagnosis in the mother is now more reliable due to improvements in serological techniques, while in the foetus the use of foetal vascular techniques has made it possible to detect those who are infected. Owing to a new and effective therapeutic method certain foetuses can now be treated successfully in utero, so that induced abortion is reserved to cases with severe and early toxoplasmosis. The contribution of new molecular biology techniques to advances in this ever moving field is explained.
Service de Médecine et de Biologie foetales, Institut de Puériculture de Paris.
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V
Mirlesse
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Jacquemard
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F
Daffos
D000328:Adult; D004359:Drug Therapy, Combination; D005260:Female; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis / Q000188:drug therapy; D011296:Prenatal Diagnosis; D011739:Pyrimethamine / Q000627:therapeutic use; D015572:Spiramycin / Q000627:therapeutic use; D013411:Sulfadiazine / Q000627:therapeutic use; D014125:Toxoplasmosis, Congenital / Q000175:diagnosis* / Q000188:drug therapy
D013411:Sulfadiazine; D015572:Spiramycin; D011739:Pyrimethamine
Toxoplasmose au cours de la grossesse. Diagnostic et nouvelles possibilités thérapeutiques.