[A case of Jordans' anomaly].
A 71 year-old female with jordans' anomaly was described. Fat-containing vacuoles were observed in neutrophils, eosinophils, basophils, monocytes and lymphocytes of the peripheral blood, but not in erythrocytes and platelets. In the bone marrow they were also observed in myeloid cells including myeloblasts, erythroblasts and megakaryocytes. In the granulocyte series, numbers of vacuole-containing cells and numbers of vacuoles increased as leukocytes matured. Histochemically, vacuoles were thought to contain neutral fat based on staining with Sudan III. However serum lipids showed no abnormalities. Both the reduction rate of NBT and the phagocytic activities for Candida albicans were normal.
Hamada
K
K
Department of Central Laboratory, Kochi Municipal Central Hospital.
Takahashi
I
I
Nakamura
T
T
Nakada
H
H
Yorimitsu
S
S
Kubonishi
I
I
Outsuki
Y
Y
D000368:Aged; D001854:Bone Marrow Cells; D005260:Female; D006098:Granulocytes / Q000378:metabolism; D006801:Humans; D007962:Leukocytes / Q000166:cytology; D050356:Lipid Metabolism; D008052:Lipid Metabolism, Inborn Errors / Q000378:metabolism*; D014617:Vacuoles / Q000378:metabolism*