Kasabach-Merritt syndrome with profound platelet support.
The Kasabach-Merritt Syndrome describes thrombocytopenia occurring in patients with giant hemangiomata. The resultant thrombocytopenia may be profound and occasionally even life-threatening. An 11-month-old infant with prolonged thrombocytopenia whose course was complicated by recurrent hemorrhaging requiring intense platelet transfusions is reported. During her 19-month hospitalization she received 6,622 platelet concentrates. This represents the most extensive platelet support ever given to an infant with this syndrome.
Henley
J D
JD
Department of Pathology, Indiana University Medical Center, School of Medicine, Indianapolis 46202-5283.
Danielson
C F
CF
Rothenberger
S S
SS
Hsueh
Y
Y
Thelia
A
A
McCarthy
L J
LJ
D016913:Blood Component Transfusion; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000150:complications / Q000473:pathology; D005260:Female; D006391:Hemangioma / Q000097:blood* / Q000473:pathology; D006801:Humans; D007223:Infant; D017713:Platelet Transfusion; D013577:Syndrome; D013921:Thrombocytopenia / Q000097:blood* / Q000473:pathology