Results of renal transplantation in boys treated for posterior urethral valves.
The results of renal transplantation in boys treated for posterior urethral valves were evaluated and compared with a matched control group. Patient and graft survival was equal in both groups, although serum creatinine levels were slightly higher in the posterior urethral valves group. Postoperative complications, such as urinary tract infections, occurred more frequently in the posterior urethral valves group. Urodynamic evaluation was performed before transplantation in 11 of 20 patients. Adequate treatment of bladder dysfunction, such as poor compliance and/or hyperreflexia, is essential in diminishing the risks of secondary graft damage due to severe bladder dysfunction.
Groenewegen
A A
AA
Department of Pediatric Urology, Sophia Children's Hospital, Erasmus University of Rotterdam, The Netherlands.
Sukhai
R N
RN
Nauta
J
J
Scholtmeyer
R J
RJ
Nijman
R J
RJ
D002648:Child; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000453:epidemiology; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D014521:Urethra / Q000002:abnormalities*; D014547:Urinary Diversion; D014552:Urinary Tract Infections / Q000453:epidemiology; D014563:Urodynamics / Q000502:physiology