[Changes in the retinal structural elements in the early and late periods after neutron exposure].
Local fractionated exposure of a rabbit eye to fast neutrons of 3 Gy (1.5 x 2) and 7.5 Gy (1.5 x 5) induces early reactions of all structural elements of retina, among which dose-dependent degradation of photoreceptor membrane discs and damages to pigmentoepitheliocytes are of prime importance. Further pathomorphogenesis is connected with the surpassing degeneration of a radial glia with respect to destruction of interneuronal synapses and a minor part of neurons. The postirradiation (one and six months after 7.5 Gy irradiation) changes in the blood-retinal barrier are responsible for the disturbances in the glioneuronal complex.
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SV
Logvinov
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NP
Buĭmova
D000818:Animals; D001813:Blood-Retinal Barrier / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005214:Fast Neutrons; D008297:Male; D008854:Microscopy, Electron; D009474:Neurons / Q000528:radiation effects / Q000648:ultrastructure; D010857:Pigment Epithelium of Eye / Q000528:radiation effects / Q000648:ultrastructure; D011817:Rabbits; D012160:Retina / Q000528:radiation effects* / Q000648:ultrastructure; D013569:Synapses / Q000528:radiation effects / Q000648:ultrastructure; D013997:Time Factors
Izmeneniia strukturnykh élementov setchatki v rannie i otdalennye sroki posle neĭtronnogo vozdeĭstviia.