Preventive effect of Spirulina maxima on the fatty liver induced by a fructose-rich diet in the rat, a preliminary report.
Cyanobacteria Spirulina maxima from Texcoco Lake in Mexico was administered as a 5% component of a purified diet, to Wistar rats together with a high percentage of fructose (60%) and its effect on several lipid fractions of plasma and liver was studied and compared to those of rats fed purified diets containing 60% of glucose or 60% of fructose. A preventive effect of Spirulina maxima on the fructose-induced increase of the liver triglycerides level was observed together with an elevation of the phospholipid concentration in this tissue. On the other hand Spirulina maxima produced a plasma cholesterol level even lower than that observed in the control group.
Departamento de Bioquímica, Facultad de Medicina, UNAM, México, D.F.
C
C
González de Rivera
R
R
Miranda-Zamora
J C
JC
Díaz-Zagoya
M A
MA
Juárez-Oropeza
D000818:Animals; D001835:Body Weight; D002784:Cholesterol / Q000097:blood / Q000378:metabolism; D000458:Cyanobacteria; D004032:Diet; D005234:Fatty Liver / Q000378:metabolism / Q000517:prevention & control*; D005632:Fructose / Q000494:pharmacology*; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D009929:Organ Size; D010743:Phospholipids / Q000097:blood / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000097:blood / Q000378:metabolism
D008055:Lipids; D010743:Phospholipids; D014280:Triglycerides; D005632:Fructose; D002784:Cholesterol