[Efficacy of and tolerance to a new NSAID in the treatment of arthrosis: droxicam. Randomized study versus tenoxicam].
A four-week open study was carried out to evaluate the efficacy and tolerability of droxicam, a new NSAID, in the treatment of painful osteoarthritis (OA). The results were compared with those obtained treating a similar group of patients with tenoxicam, at the same dosage of 20 mg/day, orally administered. The study showed that both drugs are effective in treating OA, with a mild predominance of droxicam in decreasing pain, functional limitation and chronic inability score. Tolerability was excellent or good in over 70% of patients and only one subject of each group was dropped out for severe side-effects. According to the Authors droxicam has shown to be an effective analgesic and anti-inflammatory agent as judged by its efficacy on pain relief and joint mobility in OA.
Insituto Ortopedico Gaetano Pini, Università degli Studi di Milano.
M
M
Chevallard
C
C
Venegoni
B
B
Colombo
D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D010894:Piroxicam / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011725:Pyridines / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011725:Pyridines; D010894:Piroxicam; C049073:droxicam; C032801:tenoxicam
Efficacia e tollerabilità di un nuovo FANS nella terapia dell'artrosi: il droxicam. Studio randomizzato versus tenoxicam.