Aspergillosis: advances in immunological diagnosis and therapeutic measures.
Invasive aspergillosis has become the most frequent cause of death due to opportunistic infections in hematological units where neutropenic patients and bone marrow transplant patients are treated. This is largely a consequence of the difficulty of establishing an early clinical or microbiological diagnosis, and the ensuing delay in starting antifungal therapy. Furthermore, the more effective treatment is not really codified. In this article, we make a review of advances in immunological diagnosis and in therapy against invasive aspergillosis for the last years.
Laboratoire de Parasitologie et de Mycologie, Hôpital Saint-Louis, Paris, France.
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Feuilhade de Chauvin
D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000946:Antigens, Fungal / Q000032:analysis*; D001228:Aspergillosis / Q000175:diagnosis / Q000188:drug therapy*; D001230:Aspergillus / Q000276:immunology*; D006801:Humans; D008081:Liposomes; D012698:Serologic Tests / Q000379:methods
D000935:Antifungal Agents; D000946:Antigens, Fungal; D008081:Liposomes