More on adducts and addicts. Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.
Coggon
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MRC Environmental Epidemiology Unit, Southampton General Hospital, UK.
D000107:Acetylation; D000588:Amines / Q000009:adverse effects / Q000378:metabolism*; D001191:Arylamine N-Acetyltransferase / Q000235:genetics* / Q000378:metabolism; D002273:Carcinogens / Q000009:adverse effects / Q000378:metabolism*; D016022:Case-Control Studies; D018736:DNA Adducts / Q000096:biosynthesis; D005838:Genotype; D006801:Humans; D009784:Occupational Diseases / Q000139:chemically induced / Q000201:enzymology* / Q000235:genetics; D016273:Occupational Exposure; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced / Q000201:enzymology* / Q000235:genetics
D000588:Amines; D002273:Carcinogens; D018736:DNA Adducts; D001191:Arylamine N-Acetyltransferase