[Importance of mutations interfering with mouse development].
In the mouse several point mutations and a great variety of chromosomal rearrangements are available. They all represent useful tools for experimental studies in developmental biology. This review provides, with the help of a few examples, an overview of the importance of the mouse for studies of the genetics of mammalian development.
Unité de Génétique des Mammifères, Institut Pasteur, Paris, France.
J L
JL
Guenet
D000818:Animals; D002869:Chromosome Aberrations / Q000196:embryology / Q000235:genetics; D025063:Chromosome Disorders; D005314:Embryonic and Fetal Development / Q000235:genetics*; D005260:Female; D005796:Genes; D005804:Genes, Lethal; D006239:Haplotypes; D008297:Male; D051379:Mice / Q000196:embryology* / Q000235:genetics; D009154:Mutation; D009630:Nondisjunction, Genetic; D014178:Translocation, Genetic; D014314:Trisomy
Intérêt des mutations interférant avec le développement de la souris.