Cyclic peptides, acyclic diterpene glycosides and other compounds from Lycium chinense Mill.
The chemical structures of four cyclic peptides, lyciumins A-D (1-4), three acyclic diterpene glycosides, lyciumosides I-III (5-7) and other three compounds, a tryptophan derivative glycoside (8), a monoterpene glycoside (9) and a steroidal glycoside (10) isolated from Lycium chinense, have been elucidated by a combination of chemical, 1H- and 13C-NMR, and mass spectrometric studies. Lyciumins are interesting because of their monocyclic octapeptides containing a novel C-N linkage between tryprophan N1 and glycine C alpha.
Faculty of Pharmaceutical Sciences, Kumamoto University, Japan.
S
S
Yahara
C
C
Shigeyama
T
T
Ura
K
K
Wakamatsu
T
T
Yasuhara
T
T
Nohara
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*
D000596:Amino Acids; D004224:Diterpenes; D006027:Glycosides; D010456:Peptides, Cyclic