Simultaneous optimization of pH and micelle concentration in micellar liquid chromatography.
A retention model for ionizable compounds in micellar liquid chromatography is derived and verified. The use of the model for the prediction of retention is illustrated and appropriate optimization strategies for the separation of ionizable compounds in Micellar Liquid Chromatography are discussed.
Chemistry Department, University of New Orleans, Lakefront, LA 70148.
A H
AH
Rodgers
J K
JK
Strasters
M G
MG
Khaledi
D002853:Chromatography, Liquid / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D008823:Micelles; D008956:Models, Chemical; D013056:Spectrophotometry, Ultraviolet
D008823:Micelles