Myocardial infarction induced by coronary vasospasm after self-administration of epinephrine.
A case of a 30-year-old man who developed a myocardial infarction after self-administering an Epi-Pen for an episode of idiopathic anaphylaxis is reported. The patient had numerous risk factors for coronary artery disease, and it was suspected that epinephrine-induced coronary spasm caused the infarct. The Epi-Pen Junior may be indicated in such adults with numerous risk factors for coronary artery disease who are at risk for recurrent anaphylaxis.
Department of Medicine, Medical College of Wisconsin, Milwaukee.
R
R
Saff
A
A
Nahhas
J N
JN
Fink
D000328:Adult; D000707:Anaphylaxis / Q000188:drug therapy; D003327:Coronary Disease / Q000453:epidemiology; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000150:complications*; D004837:Epinephrine / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology*; D012307:Risk Factors; D012646:Self Administration
D004837:Epinephrine