[The effect of creatine phosphate (Neoton) in acute myocardial infarct (a prospective multicenter pilot study].
The authors investigated in a group of 106 patients with a first myocardial infarction treated by thrombolysis the effect of i.v. administration of creatine phosphate (a new drug with cardioprotective action--Neoton Alfa Schiapparelli Wassermann Co). In the course of treatment electrocardiographic changes were recorded and the presence of arrhythmias examined by the Holter technique. The Neoton group displayed a statistically insignificant but nevertheless obvious trend of electrocardiographically less serious forms of infarction and a lower incidence of infarctions, as compared with the control group.
Stejfa
M
M
I. interní klinika FN u sv. Anny, Brno.
Zeman
K
K
Groch
L
L
Marek
J
J
Komárek
J
J
Janota
T
T
Vávra
F
F
Kölbel
F
F
Charvát
I
I
Weinbergová
O
O
D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D010725:Phosphocreatine / Q000627:therapeutic use*; D010865:Pilot Projects; D011446:Prospective Studies; D015912:Thrombolytic Therapy
D010725:Phosphocreatine
Ucinek kreatinfosfátu (Neoton) u akutního srdecního infarktu (pilotní multicentrická prospektivní studie).