Combined oesophageal adenocarcinoma and carcinoid in Barrett's oesophagitis: potential role of enterochromaffin-like cells in oesophageal malignancy.
A case of combined adenocarcinoma and carcinoid tumour which occurred in a patient with a Barrett's oesophagus is presented. Its significance is discussed in relation to the potential role of enterochromaffin-like cells in the development of oesophageal malignancy, and the possibility is raised that long term treatment with omeprazole, commonly used in this condition, could promote this.
Department of Pathology, Papworth Hospital, Everard, Cambridge.
N R
NR
Cary
D J
DJ
Barron
J P
JP
McGoldrick
F C
FC
Wells
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D001471:Barrett Esophagus / Q000150:complications / Q000473:pathology*; D001706:Biopsy; D002276:Carcinoid Tumor / Q000150:complications / Q000473:pathology; D004759:Enterochromaffin Cells / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged