Acetylcholine level in the brain and other organs of the bivalve Anodonta cygnea L. and its modification by heavy metals.
Acetylcholine was detected and measured in the ganglia (60-80 nmol/g), in the heart (10-15 nmol/g) and in the adductor muscles (4-5 nmol/g) of the bivalve Anodonta cygnea L. using gas chromatographic determination. Treatment of the animals with low concentration of heavy metals, which cause change in the behaviour, resulted in decrease of the brain acetylcholine level. Within 7 days treatment Cu2+ caused 80 per cent, Cd2+ and Pb2+ 30 per cent reduction with varying types of recovery after wash.
Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany.
J
J
Salánki
D
D
Budai
L
L
Hiripi
P
P
Kása
D000109:Acetylcholine / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D002104:Cadmium / Q000494:pharmacology; D003300:Copper / Q000494:pharmacology; D006321:Heart / Q000187:drug effects; D007854:Lead / Q000494:pharmacology; D008670:Metals / Q000494:pharmacology*; D009132:Muscles / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D009420:Nervous System / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*; D012908:Snails / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*
D008670:Metals; D002104:Cadmium; D007854:Lead; D003300:Copper; D000109:Acetylcholine