Simple column liquid chromatographic assay for serum neopterin.
A simple high-performance liquid chromatographic assay for serum neopterin with highly sensitive fluorimetric detection (limit 1 nM) is proposed. Comparison with results obtained by radioimmunoassay revealed a good correlation between the two techniques. The potential use of this method for the follow-up of liver transplant patients is discussed.
Laboratoire de Biochimie, Hôpital Pasteur, Nice, France.
M
M
Candito
C
C
Cavenel
J
J
Gugenheim
J
J
Mouiel
F
F
Parisot
Y
Y
Jacomet
P
P
Sudaka
P
P
Chambon
D000328:Adult; D001708:Biopterins / Q000031:analogs & derivatives* / Q000097:blood / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D015394:Molecular Structure; D019798:Neopterin; D011863:Radioimmunoassay; D013050:Spectrometry, Fluorescence
D001708:Biopterins; D019798:Neopterin