[Intravenous administration of gadolinium DPTA in proton spin tomography of the knee joint].
In a prospective study we evaluated the benefits of iv-application of gadolinium-DPTA examining 25 patients with degenerative disease of the knee joint by MRI (1.0 Tesla). All patients were scanned with standard spin echo sequences (SE 500/20), short time inversion recovery sequences (STIR 1600/100), and FEDIF sequences (FEDIF 500/10). After gadolinium-DPTA application (0.1-0.35 mmol/kg BW) the patients were scanned with spin echo sequences (SE SE 500/20), and FEDIF sequences (FEDIF 500/10). After iv-Gadolinium the synovial membrane of joints with inflammation show significant increase of the signal. Due to this effect a differentiation between joint effusion and hypertrophic synovia is possible. Small areas of local synovitis not visible before the use of gadolinium can be documented. A differentiation between degenerative subchondral cysts and cysts due to an inflammatory process is possible.


CONCLUSIONS
The use of iv-application of gadolinium-DPTA in patients with degenerative joint disease seems to offer additional information. With iv-application all shortcomings of intraarticular use can be avoided. The differentiation between degenerative and inflammatory processes is possible.
Jerosch
J
J
Klinik und Poliklinik für Allgemeine Orthopädie, Westfälische-Wilhelms-Universität Münster.
Lahm
A
A
Castro
W H
WH
Assheuer
J
J
D003287:Contrast Media; D005122:Exudates and Transudates; D005682:Gadolinium; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis; D007719:Knee Joint / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D011446:Prospective Studies; D013583:Synovial Membrane / Q000473:pathology; D013585:Synovitis / Q000175:diagnosis
D003287:Contrast Media; D005682:Gadolinium
Intravenöse Anwendung von Gadolinium DPTA bei der Kernspintomographie des Kniegelenkes.