[A case report: multiple liver metastasis of gastric cancer responding to intraarterial infusion of MTX and 5-FU].
In a 63-year-old male patient with gastric cancer having multiple liver metastases, the metastatic lesions responded well to postoperative staggered intraarterial infusion therapy with MTX and 5-FU. The intraarterial infusion therapy was administered once a week. A total of 5 courses of this therapy produced marked regression of liver metastases and remarkable necrosis. The effect was thus rated as PR. The patient is healthy and has been successfully rehabilitated. His dose is oral 5-FU (200 mg x 2).
Dept. of Surgery, Tagawa City Hospital.
Y
Y
Ota
Y
Y
Nakano
H
H
Yamaguchi
K
K
Yoshida
T
T
Shirafuji
A
A
Adachi
D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D006801:Humans; D007261:Infusions, Intra-Arterial; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery
D002955:Leucovorin; D005472:Fluorouracil; D008727:Methotrexate