Oxygen transport in peripheral arterial occlusive disease: effects of calf blood dialysate.
The obvious relationship of arterial blood flow to tissue hypoxia has led to the relative neglect of secondary mechanisms that might influence the functional and morphologic consequences of major vessel obstruction. Oxygen diffusion through capillaries, both locally and systemically, may be disturbed in subjects with chronic local ischemia. Follow-up data after a double-blind, placebo-controlled evaluation of the effect of treatment with a calf blood dialysate confirm that such treatment may alleviate the consequences of peripheral arterial obstructive disease even though there is no improvement in blood flow through the arterial system involved.
Department of Analgesia, Regional General Hospital, Ancona, Italy.
C
C
Rossano
M
M
Weiner
E
E
Haigis
D000818:Animals; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000145:classification / Q000453:epidemiology / Q000628:therapy*; D001685:Biological Factors / Q000008:administration & dosage*; D001769:Blood; D002417:Cattle; D004311:Double-Blind Method; D005500:Follow-Up Studies; D006801:Humans; D010101:Oxygen Consumption / Q000187:drug effects*; D010147:Pain Measurement / Q000706:statistics & numerical data; D010313:Partial Pressure; D006435:Renal Dialysis; D013997:Time Factors
D001685:Biological Factors