Rheumatoid nodules at the cement-bone interface in revision arthroplasty of rheumatoid patients.
We studied the histology of the cement-bone interface and the regenerated synovium in ten aseptically loosened arthroplasties in rheumatoid patients. In two patients we found rheumatoid nodules at the cement-bone interface and marked lymphoplasmacytic infiltration in another three. Failed joints in osteoarthritic patients did not show these changes, and it seems likely that the presence of abundant immunocompetent cells was due to the background disease. We speculate that rheumatoid inflammation contributed to the process of loosening.
Department of Orthopaedic Surgery, Shiga University of Medical, Japan.
K
K
Inoue
J
J
Nishioka
S
S
Hukuda
K
K
Shichikawa
H
H
Okabe
D000328:Adult; D000368:Aged; D001171:Arthritis, Juvenile / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D001706:Biopsy; D001843:Bone Cements; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation; D012218:Rheumatoid Nodule / Q000473:pathology*; D013583:Synovial Membrane / Q000473:pathology*; D013997:Time Factors
D001843:Bone Cements