[Significance of monoclonal macroglobulinemia].
A monoclonal IgM protein in the plasma results from an expansion of a B lymphoid clone which encompasses a spectrum of different diseases: transient clones, monoclonal gammopathy of undetermined significance, Waldenström's macroglobulinemia and other B lymphoid malignancies, or primary amyloidosis. The main symptoms are related to the M component concentration and specific properties, the tumor development or both. Prognosis best correlates with the underlying histologic disorder.
Service d'hématologie clinique, centre hospitalier universitaire, Caen.
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Leporrier
D000368:Aged; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D008259:Macroglobulins / Q000276:immunology; D008297:Male; D008875:Middle Aged; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000276:immunology*; D008258:Waldenstrom Macroglobulinemia / Q000276:immunology*
D007075:Immunoglobulin M; D008259:Macroglobulins
Signification d'une macroglobulinémie monoclonale.