Hereditary non-polyposis colorectal cancer (Lynch syndrome I) in a 13 year old male.
A case of adenocarcinoma of the colon is reported. It presented in a family with hereditary non-polyposis colorectal cancer (HNPCC). Colonoscopic screening at a young age is recommended in such families. It also suggests a genetic basis for colorectal carcinogenesis in this family. Three of the members of this family also have peptic ulceration and an association between this syndrome and HNPCC is postulated.
Moorabbin Campus, Monash Medical Centre, Melbourne, Victoria, Australia.
I G
IG
Faragher
C J
CJ
Cox
A
A
Stevenson
D000293:Adolescent; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D010437:Peptic Ulcer / Q000235:genetics