[Testicular microcirculation in rats measured with laser-Doppler flowmetry].
Study carried out in 50 male Wistar rats distributed into 5 groups: baseline and at 2, 4, 8 and 24 hours after subcutaneous injection of Human Chorionic Gonadotropin, 100 IU. It was observed that testicular microcirculatory flow shows a rhythmical fluctuating pattern (5-10 fluctuations per minute), which becomes continuous at 4 hours but recovers at 24 hours. At the same time, there is an increased volume of testicular interstitial fluid that peaks at 8 hours, and returns to baseline levels at 24 hours. Serum testosterone values increase with HCG injection, reaching a peak at 4 hours (25.9 mg/ml), to return to nearly baseline levels at 24 hours (5.04 mg/ml). Disappearance of the rhythmical microcirculatory pattern, and the increase of interstitial fluid volume do not appear to be mediated by testosterone, since the raise in hormone levels, occurred after HCG administration, preceded the observed microcirculatory changes.
Servicio de investigaciones biotecnológicas, Hospital General Universitario de Valencia.
V
V
Gonzalvo
M A
MA
Calvo
P
P
Navalón
L O
LO
Gimeno
F J
FJ
Ramada
D
D
Cejalvo
J E
JE
Blasco
J
J
Zaragozá
J M
JM
Lloris
D000818:Animals; D006063:Chorionic Gonadotropin / Q000008:administration & dosage; D017078:Laser-Doppler Flowmetry; D008297:Male; D008833:Microcirculation; D010507:Periodicity; D051381:Rats; D013737:Testis / Q000098:blood supply*; D013739:Testosterone / Q000097:blood
D006063:Chorionic Gonadotropin; D013739:Testosterone
Microcirculación testicular en la rata medida mediante flujometría laser doppler.