Resolution of danazol-induced cholestasis with S-adenosylmethionine.
In a case of danazol-induced cholestasis, the anti-cholestatic agent S-adenosylmethionine was given intravenously for 3 weeks and then orally for 6 weeks. This was well tolerated and led to prompt resolution of both jaundice and associated renal impairment.
Bray
G P
GP
Institute of Liver Studies, King's College Hospital School of Medicine and Dentistry, London, UK.
Tredger
J M
JM
Williams
R
R
D000284:Administration, Oral; D002779:Cholestasis / Q000139:chemically induced / Q000188:drug therapy*; D003613:Danazol / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D012436:S-Adenosylmethionine / Q000627:therapeutic use*; D013997:Time Factors
D012436:S-Adenosylmethionine; D003613:Danazol