[Brief history of AIDS in non-human primates and its contribution to the study of acquired immunodeficiency syndrome].
Infection of the rhesus monkey (Macaca mulatta) with retroviruses originating from African non human primates (SIV) induces in this species an acquired immunodeficiency syndrome (SAIDS) closely resembling AIDS in humans. Analogies between the SIV-rhesus system and AIDS in humans are described in this work, analyzing the close relationship existing between the HIV and SIV viruses, and the similarities between SIV disease in the rhesus and HIV disease in humans. A review of current advances in AIDS vaccine research, using the SIV-rhesus model, is also included.
Centro de Recursos Animales, Universidad de Puerto Rico, San Juan 00936-5067.
C A
CA
Málaga
E
E
Kraiselburd
J A
JA
Lavergne
A M
AM
Del Llano
J P
JP
Amieiro
D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology; D000818:Animals; D004195:Disease Models, Animal; D006678:HIV / Q000235:genetics; D006801:Humans; D008253:Macaca mulatta; D016097:Simian Acquired Immunodeficiency Syndrome / Q000382:microbiology / Q000517:prevention & control; D015302:Simian Immunodeficiency Virus; D014612:Vaccines
D014612:Vaccines
Breve historia del SIDA en los primates no humanos y su contribución al estudio del síndrome de inmunodeficiencia adquirida.