Migrating myoelectric complex and jejunal slow-wave propagation after Roux gastrectomy in dogs.
Roux-en-Y gastrectomy is associated with a high incidence of symptoms of gastric stasis. Retrograde propagation of jejunal electrical slow waves and spike bursts has been implicated in the Roux Y stasis syndrome. Since the fasted state may persist after feeding, this study examined the extent of retrograde slow-wave propagation in the fasted state, particularly during aboral migration of phase III. Six dogs underwent Roux gastrectomy and placement of bipolar electrodes along the Roux limb. Four normal dogs with electrodes acted as controls. Thirty-five migrating myoelectric complexes were recorded in Roux dogs and 13 in controls. In Roux dogs, the incidences of retrograde propagation of slow waves during the migrating myoelectric complex were phase I 56 +/- 13%, phase II 60 +/- 12% and phase III 58 +/- 14% (not significant). For controls, the incidences were 0%, 0%, and 1%, respectively (P < 0.006 versus Roux dogs). In the Roux limb, retrograde propagation of slow waves, and hence spike bursts, occurs even during aboral migration of phase III. This abnormality may contribute to the Roux Y stasis syndrome.
Department of Surgery, VAMC, Syracuse, New York.
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Woodward
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Sillin
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Bortoff
D000713:Anastomosis, Roux-en-Y; D000818:Animals; D004285:Dogs; D004567:Electrodes, Implanted; D005215:Fasting / Q000502:physiology; D005743:Gastrectomy / Q000379:methods*; D007583:Jejunum / Q000502:physiology*; D016065:Myoelectric Complex, Migrating; D011178:Postgastrectomy Syndromes / Q000209:etiology / Q000503:physiopathology; D011184:Postoperative Period