Moebius syndrome associated with pituitary dwarfism and hypoplastic optic disc.
A 17 year old male patient with Moebius syndrome with pituitary dwarfism and unilateral hypoplastic optic disc is presented. Although there have been several reports of an association of Moebius syndrome and pituitary dysfunction, growth hormone deficiency has not been reported previously. These associations may give some insight into the pathogenesis of Moebius syndrome.
Department of Pediatrics, Faculty of Medicine, University of Tokyo, Japan.
N
N
Hashimoto
Y
Y
Sakakihara
Y
Y
Miki
J
J
Kagawa
S
S
Egi
S
S
Kamoshita
D000293:Adolescent; D004393:Dwarfism, Pituitary / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy; D005158:Facial Paralysis / Q000151:congenital* / Q000175:diagnosis; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009886:Ophthalmoplegia / Q000151:congenital* / Q000175:diagnosis; D013577:Syndrome
D013006:Growth Hormone