[Sevoflurane anesthesia in a patient following renal transplantation].
A 29-year-old male after renal transplantation with aseptic necrosis of the head of the left femur was anesthetized with sevoflurane-nitrous oxide-oxygen for replacement surgery. Anesthesia was induced with N2O 4 l.min-1, O2 2 l.min-1, plus sevoflurane and maintained with N2O4 l.min-1, O2 2 l.min-1 and sevoflurane. Sevoflurane concentrations ranged from 1% to 4%. The serum inorganic fluoride showed the peak level of 38.4 microM.l-1 about 60 minutes after discontinuation of sevoflurane a decrease in serum inorganic fluoride was delayed. Urinary N-acetyl-beta-D-glucosaminidase (NAG), gamma-glutamyl transpeptidase (gamma-GTP) and beta 2-microglobulin (beta 2-m) increased over five postoperative days. NAG and gamma-GTP returned to the preanesthetic level on the 6th postoperative day, but beta 2-m higher than the preanesthetic level lasted for 14 postoperative days. In conclusion, sevoflurane brought about little effect on the transplanted kidney in this patient.
Department of Anesthesiology, Jichi Medical School, Tochigi.
K
K
Saitoh
Y
Y
Hirabayashi
H
H
Fukuda
R
R
Shimizu
D000328:Adult; D000769:Anesthesia, Inhalation; D004987:Ethers; D005271:Femur Head Necrosis / Q000601:surgery*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008738:Methyl Ethers; D009609:Nitrous Oxide; D000077149:Sevoflurane
D004987:Ethers; D008738:Methyl Ethers; D000077149:Sevoflurane; D009609:Nitrous Oxide