Memory functions and temporal-limbic morphology in schizophrenia.
Several psychopathological and morphological studies support the hypothesis of temporal-limbic involvement in the pathophysiology of schizophrenia. In the present study, magnetic resonance imaging was used to evaluate the areas of the temporal lobes and related structures in 18 schizophrenic patients and 18 normal control subjects who were homogeneous for sex and age. The Wechsler Memory Scale was used to assess the memory functions of all subjects. Although the MRI data did not reveal any significant differences between the two groups, the Wechsler Memory Scale indices of memory functions showed significant differences between the schizophrenic patients and the control subjects.
Colombo
C
C
Department of Biomedical and Technological Sciences, University of Milan Medical School, Italy.
Abbruzzese
M
M
Livian
S
S
Scotti
G
G
Locatelli
M
M
Bonfanti
A
A
Scarone
S
S
D000328:Adult; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008032:Limbic System / Q000473:pathology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory / Q000502:physiology*; D012559:Schizophrenia / Q000473:pathology* / Q000503:physiopathology; D012565:Schizophrenic Psychology; D013702:Temporal Lobe / Q000473:pathology* / Q000503:physiopathology; D014888:Wechsler Scales