Properties and stereoselectivity of carbonyl reductases involved in the ketone reduction of warfarin and analogues.
Dept. Pharmacology, University of Limburg, Maastricht, The Netherlands.
J J
JJ
Hermans
H H
HH
Thijssen
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000429:Alcohol Oxidoreductases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000818:Animals; D003600:Cytosol / Q000201:enzymology; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007223:Infant; D007659:Ketones / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D010084:Oxidation-Reduction; D011817:Rabbits; D013237:Stereoisomerism; D014859:Warfarin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism*
D007659:Ketones; D014859:Warfarin; D000429:Alcohol Oxidoreductases