Systemic Pneumocystis carinii pneumonia prophylaxis with dapsone and pyrimethamine fails to protect against extrapulmonary pneumocystosis.
Extrapulmonary pneumocystosis is a feature of severe immunosuppression which earlier reports have suggested is limited to patients receiving either no prophylaxis or aerosolised pentamidine. We report a case of disseminated pneumocystosis which developed in an HIV positive homosexual man despite systemic primary Pneumocystis carinii pneumonia prophylaxis.
Carlin
E M
EM
Department of Genitourinary Medicine, St. Mary's Hospital, London, UK.
Coker
R J
RJ
Goldin
R D
RD
Harris
J R
JR
D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control*; D000280:Administration, Inhalation; D000328:Adult; D003622:Dapsone / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D011020:Pneumonia, Pneumocystis / Q000517:prevention & control*; D011739:Pyrimethamine / Q000008:administration & dosage / Q000627:therapeutic use*
D003622:Dapsone; D011739:Pyrimethamine