Wound botulism in a patient with a tooth abscess: case report and review.
We describe a case of wound botulism associated with a tooth abscess in a 5-year-old boy. We reviewed the literature and reports to the Centers for Disease Control and Prevention (Atlanta) of laboratory-confirmed cases of wound botulism. From 1943 through 1990, 47 cases were reported. Type A botulinus toxin was identified in 32 cases, type B in 13, types A and B in 1, and an unknown type in 1. Botulism was associated with wounds from trauma, use of injectable drugs, and surgery. Sinusitis after use of intranasal cocaine has also been associated with botulism. Treatment for wound botulism includes prompt debridement of the wound for eliminating anaerobic conditions, intensive care, and treatment with antitoxin.
Weber
J T
JT
Division of Bacterial and Mycotic Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
Goodpasture
H C
HC
Alexander
H
H
Werner
S B
SB
Hatheway
C L
CL
Tauxe
R V
RV
D001905:Botulinum Toxins / Q000302:isolation & purification; D001906:Botulism / Q000175:diagnosis*; D002675:Child, Preschool; D003646:Debridement; D003731:Dental Caries / Q000150:complications* / Q000628:therapy; D006801:Humans; D008297:Male; D010508:Periodontal Abscess / Q000150:complications* / Q000628:therapy; D014081:Tooth Extraction; D014094:Tooth, Deciduous; D014946:Wound Infection / Q000382:microbiology*
D001905:Botulinum Toxins