Inverse relationship between IgE and worm burdens in cattle infected with Ostertagia ostertagi.
Changes in serum total and Ostertagia-specific IgE levels, and pepsinogen concentrations were evaluated in 28 Holstein calves naturally or experimentally infected with Ostertagia ostertagi. In addition, IgE and pepsinogen concentrations were determined in abomasal lymph. Results showed that (1) lymph IgE responses were inversely correlated with worm burdens, and (2) serum IgE levels were unreliable for predicting worm burdens.
Department of Veterinary Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis 95616.
D G
DG
Baker
L J
LJ
Gershwin
D000818:Animals; D000909:Antibodies, Helminth / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology* / Q000469:parasitology; D007073:Immunoglobulin E / Q000276:immunology*; D008196:Lymph / Q000276:immunology*; D008297:Male; D010029:Ostertagiasis / Q000276:immunology / Q000662:veterinary*; D010435:Pepsinogens / Q000097:blood; D012044:Regression Analysis
D000909:Antibodies, Helminth; D010435:Pepsinogens; D007073:Immunoglobulin E