A review of the Japanese Pharmaceutical Manufacturers' Association database currently established to examine retrospectively the value of long-term animal toxicity studies.
Igarashi
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R&D Information Management, Eisai Co. Ltd, Tokyo, Japan.
D000818:Animals; D002626:Chemistry, Pharmaceutical / Q000592:standards; D016206:Databases, Bibliographic / Q000592:standards; D004285:Dogs; D064420:Drug-Related Side Effects and Adverse Reactions; D005069:Evaluation Studies as Topic; D012189:Retrospective Studies; D013997:Time Factors; D014116:Toxicology / Q000379:methods*