Successful treatment with captopril of an elderly man with polydipsia and hyponatremia.
A case of severe hyponatremia in a polydipsic 64-year-old man is described. He was unsuccessfully treated with both demeclocycline and lithium carbonate. However, low-dose captopril reversed the polydipsia and resulted in sustained normal serum sodium levels. We believe the antidipsogenic effect of captopril may benefit some patients with polydipsia and hyponatremia.
University of Florida, Department of Psychiatry, University of Florida Hospitals, Gainesville 32608.
M J
MJ
Tueth
J
J
Broderick-Cantwell
D001925:Brain Damage, Chronic / Q000150:complications* / Q000523:psychology; D003707:Demeclocycline / Q000627:therapeutic use; D004326:Drinking / Q000187:drug effects*; D004359:Drug Therapy, Combination; D006801:Humans; D007010:Hyponatremia / Q000188:drug therapy*; D016651:Lithium Carbonate / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011604:Psychoses, Alcoholic / Q000188:drug therapy* / Q000523:psychology; D014882:Water-Electrolyte Balance / Q000187:drug effects
D016651:Lithium Carbonate; D003707:Demeclocycline