Automated solid-phase extraction of opiates from urine (II). Establishing criteria for the detection of opiate abuse.
Automation in the laboratory was taken one step further with the introduction of automated solid-phase extraction of opiates from urine using C18 bonded-phase columns as an alternative to traditional liquid-liquid partitioning. A comparison of the automated procedure with an established liquid-liquid extraction procedure showed a linear correlation between the two over the concentration range studied. Criteria for the identification of opiate abusers were established to adapt this new methodology to large-scale screening of urine specimens.
Tay
M K
MK
Department of Scientific Services, Institute of Science and Forensic Medicine, Singapore.
Lee
T K
TK
Chui
W Y
WY
D003061:Codeine / Q000652:urine; D006801:Humans; D009020:Morphine / Q000652:urine; D009269:Nalorphine / Q000652:urine; D009294:Narcotics / Q000652:urine*; D015813:Substance Abuse Detection / Q000379:methods*; D016482:Urinalysis / Q000379:methods*
D009294:Narcotics; D009020:Morphine; D009269:Nalorphine; D003061:Codeine