Parentage determination on placental tissues through deoxyribonucleic acid fingerprints.
Investigation of genomic polymorphisms detected by a mini-satellite "Myo" probe gives distinct and different Deoxyribonucleic Acid (DNA) fingerprints of chorionic villus and decidual membrane in the same placenta. The chorionic villus, which is regarded as the extra-embryonal tissue, represents the essential embryonal DNA fingerprint pattern, while the decidual membrane reveals the maternal pattern. A comparison between the DNA fingerprints from the chorionic villus and from the blood sample of the suspected father provides the possibility of setting a paternity test in the early gestational stage. Twenty-eight cases of paternity test on aborted placental tissues by DNA fingerprints were analysed.
Jiang
X H
XH
DNA Analysis Laboratory, Liaoning Criminal Scientific and Technical Research Institute, People's Republic of China.
Wei
Y
Y
D000028:Abortion, Induced; D002824:Chorionic Villi / Q000737:chemistry; D016172:DNA Fingerprinting; D005260:Female; D005554:Forensic Medicine; D006801:Humans; D008297:Male; D010334:Paternity; D011247:Pregnancy