[The relation of moderate alcohol drinking and congestive heart insufficiency].
116 patients (53 women and 63 men) with congestive heart failure, secondary to chronic ischemic heart disease and/or hypertensive heart disease, were studied with the aim of assessing effects of moderate alcohol use on the clinical features of the disease. Two subgroups were considered: a) 57 moderate drinkers (11 women and 46 men); b) 59 non-drinkers or ex-drinkers (42 women, 17 men). Left ventricular mass/m2 (LVM/m2) is higher among moderate drinkers in comparison with non-drinkers (p < 0.001); this difference is present both in men (p < 0.05) and in women (p < 0.001). These results suggest that higher LVM/m2 of drinkers does not depend on sex and cigarette smoking; i.e., in males, a subgroup with the same prevalence of cigarette smokers among drinkers and non drinkers, congestive heart failure of drinkers is associated with a greater left ventricular enlargement. Our results suggest that moderate alcohol use can represent an additional pathogenetic factor for more severe clinical and laboratory features of congestive heart failure.
Carpinteri
G
G
Clinica Medica, Università, Catania.
Caruso
G
G
Mazzone
O
O
Trovato
G
G
D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects*; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects
Rapporti tra uso moderato di alcolici e insufficienza cardiaca congestizia.