Spontaneous hemorrhage associated with accidental brodifacoum poisoning in a child.
A 36-month-old child had spontaneous hemorrhage from her nose, mouth, and urinary tract, and a fall in hemoglobin of 20 gm/L (2 gm/dl). The prothrombin time and partial thromboplastin time were markedly prolonged with a decrease in the vitamin K-dependent factors. The child had ingested brodifacoum, a long-acting rodenticide. Prolonged follow-up and treatment with vitamin K were necessary.
Department of Pediatrics, Cooper Hospital/University Medical Center, Camden, New Jersey.
S F
SF
Travis
W
W
Warfield
B H
BH
Greenbaum
M
M
Molokisher
J E
JE
Siegel
D015110:4-Hydroxycoumarins / Q000506:poisoning*; D002675:Child, Preschool; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D011041:Poisoning / Q000175:diagnosis / Q000188:drug therapy; D012378:Rodenticides / Q000506:poisoning*; D014812:Vitamin K / Q000627:therapeutic use
D015110:4-Hydroxycoumarins; D012378:Rodenticides; D014812:Vitamin K; C013418:bromfenacoum