Circadian-clock regulation of gene expression.
During the past year, our understanding of the cellular and molecular processes involved in the generation and control of circadian rhythms has advanced significantly. Progress has been made at the level of the circadian pacemaker mechanism itself, the input pathways that regulate the pacemaker, and the mechanisms by which the pacemaker regulates its various outputs. A common theme underlying all three of these processes is the involvement of transcriptional and translational control. This review is an updated and extended version of a review first published in Current Opinion in Neurobiology 1991, 1:556-561.
Takahashi
J S
JS
Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208-3520.
D000828:Animal Population Groups / Q000235:genetics / Q000502:physiology; D000818:Animals; D002940:Circadian Rhythm / Q000235:genetics*; D004330:Drosophila / Q000235:genetics / Q000502:physiology; D029721:Drosophila Proteins; D005786:Gene Expression Regulation; D008957:Models, Genetic; D009687:Nuclear Proteins / Q000502:physiology; D056950:Period Circadian Proteins; D018521:Plant Physiological Phenomena; D010944:Plants / Q000235:genetics; D014176:Protein Biosynthesis; D013493:Suprachiasmatic Nucleus / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology; D014158:Transcription, Genetic
D029721:Drosophila Proteins; D009687:Nuclear Proteins; C539040:PER protein, Drosophila; D056950:Period Circadian Proteins; D014157:Transcription Factors