Radiation-induced squamous carcinoma arising within a seborrhoeic keratosis.
Seborrhoeic keratoses (SK) are common skin tumours. They are benign, and present little difficulty in management. However, rare malignant transformation is recognized. We report a case of a squamous cell carcinoma arising from dysplastic changes within a long-standing SK on the chest wall of a 75-year-old retired radiologist, and consider the role of radiation in inducing malignant change within SKs.
Department of Histopathology, St Mary's Hospital, London, U.K.
S K
SK
Suvarna
M
M
Bagary
G
G
Glazer
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D006801:Humans; D017492:Keratosis, Seborrheic / Q000150:complications* / Q000473:pathology; D008297:Male; D009381:Neoplasms, Radiation-Induced; D009784:Occupational Diseases / Q000209:etiology*; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology