[A case of vivax malaria with thrombocytopenia suggesting immunological mechanisms].
Recently, it has been shown that the thrombocytopenia that complicates some malarial infections is caused by immune mechanisms. We report a case of malaria associated with thrombocytopenia and increased platelet-associated IgG (PAIgG). In this case, anti-malarial therapy reduced the level of PAIgG to normal levels in association with normalization of the platelet count. This case suggests the immunological mechanisms of thrombocytopenia in malaria.
Ohtaka
M
M
First Department of Internal Medicine, Tokyo Medical College.
Ohyashiki
K
K
Iwabuchi
H
H
Iwabuchi
A
A
Lin
K Y
KY
Toyama
K
K
D000328:Adult; D001792:Blood Platelets / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D016780:Malaria, Vivax / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D008297:Male; D011803:Quinine / Q000008:administration & dosage; D013413:Sulfadoxine / Q000008:administration & dosage; D013921:Thrombocytopenia / Q000209:etiology*; D014195:Travel
D007074:Immunoglobulin G; D013413:Sulfadoxine; D011803:Quinine