Sialadenosis of the parotid gland: report of four cases diagnosed by fine-needle aspiration cytology.
Four patients presented with a history of recurrent bilateral swellings of parotid glands. Fine-needle aspiration (FNA) specimens showed highly cellular smears containing clusters of enlarged acini and numerous naked nuclei. A diagnosis consistent with sialadenosis was made considering the distinct morphologic appearance: micrometric measurements in all cases, in addition to histology and electron microscopy in two cases confirmed this hypothesis. A review of clinical histories revealed hormonal, nutritional and neurogenic disorders, which are known to be associated with sialadenosis. In the work-up of salivary gland swellings, it is important to recognize cytologically this underestimated entity, which does not necessarily require surgical treatment.
Department of Biopathology, University La Sapienza, Rome, Italy.
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Ascoli
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Albedi
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De Blasiis
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Nardi
D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D010305:Parotid Diseases / Q000473:pathology*; D010306:Parotid Gland / Q000473:pathology / Q000648:ultrastructure