Cryoglobulinemia and cutaneous leukocytoclastic vasculitis associated with hepatitis C virus infection.
Hepatitis C virus infection is a frequent cause of non-A, non-B hepatitis worldwide. Resultant morbidity is significant; chronic liver disease develops in 50% of infected persons. Since serologic testing has become available there have been several reports of cutaneous findings in association with hepatitis C virus infection, including vasculitis, cryoglobulinemia, urticaria, and lichen planus. We describe a patient with cryoglobulinemia, chronic cutaneous leukocytoclastic vasculitis, and hepatitis C virus infection. Hepatitis C virus infection should be included in the differential diagnosis of the causes of cryoglobulinemia and leukocytoclastic vasculitis.
Department of Dermatology, Northwestern University Medical School, Chicago, Illinois.
A S
AS
Pakula
J M
JM
Garden
S I
SI
Roth
D003449:Cryoglobulinemia / Q000209:etiology* / Q000473:pathology; D006526:Hepatitis C / Q000150:complications* / Q000473:pathology; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology / Q000473:pathology; D007868:Leg Dermatoses / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000209:etiology* / Q000473:pathology