Neutropenia associated with myelofibrosis in systemic lupus erythematosus.
Although myelofibrosis has been described in systemic lupus erythematosus (SLE), this coexistence must be rare since there are few reports showing this combination. The possible relationship between hematologic abnormalities and SLE remains unresolved. The authors describe a 39-year-old woman with persistent neutropenia and SLE in whom myelofibrosis was found. Unlike previously reported cases, myelofibrosis did not resolve with steroid therapy. In this report, the clinical course of the patient is compared with others described in the literature.
Borba
E F
EF
Department of Rheumatology, School of Medicine, University of São Paulo, Brazil.
Pereira
R M
RM
Velloso
E D
ED
Pereira
I A
IA
Goncalves
C R
CR
Yoshinari
N H
NH
D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008775:Methylprednisolone / Q000008:administration & dosage; D009503:Neutropenia / Q000097:blood / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D009504:Neutrophils / Q000187:drug effects; D011241:Prednisone / Q000008:administration & dosage; D055728:Primary Myelofibrosis / Q000097:blood / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
D011241:Prednisone; D008775:Methylprednisolone