Successful treatment with captopril of an elderly man with polydipsia and hyponatremia.
A case of severe hyponatremia in a polydipsic 64-year-old man is described. He was unsuccessfully treated with both demeclocycline and lithium carbonate. However, low-dose captopril reversed the polydipsia and resulted in sustained normal serum sodium levels. We believe the antidipsogenic effect of captopril may benefit some patients with polydipsia and hyponatremia.
Tueth
M J
MJ
University of Florida, Department of Psychiatry, University of Florida Hospitals, Gainesville 32608.
Broderick-Cantwell
J
J
D001925:Brain Damage, Chronic / Q000150:complications* / Q000523:psychology; D003707:Demeclocycline / Q000627:therapeutic use; D004326:Drinking / Q000187:drug effects*; D004359:Drug Therapy, Combination; D006801:Humans; D007010:Hyponatremia / Q000188:drug therapy*; D016651:Lithium Carbonate / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011604:Psychoses, Alcoholic / Q000188:drug therapy* / Q000523:psychology; D014882:Water-Electrolyte Balance / Q000187:drug effects
D016651:Lithium Carbonate; D003707:Demeclocycline