Deletion(2)(p23) abnormality in a case of secondary acute myeloid leukemia.
We report a case of acute myeloid leukemia (M5a of the FAB classification), secondary to the myelodysplastic syndrome, showing a deletion of the short arm of chromosome 2 at p23 in the bone marrow cells. In addition, a duplication of chromosome 13,dup(13)(q12q14) was found.
Medical Genetics Department, Hospital Ramón y Cajal, Madrid, Spain.
T
T
Ferro
I
I
Krsnik
M
M
Resino
P
P
Cabello
J M
JM
García-Sagredo
C
C
San Román
D000368:Aged; D002869:Chromosome Aberrations / Q000235:genetics*; D002872:Chromosome Deletion; D025063:Chromosome Disorders; D002889:Chromosomes, Human, Pair 2; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D009190:Myelodysplastic Syndromes / Q000150:complications*