[Systemic diseases treated by corticoids, plasma exchange and cyclophosphamide: infectious complications and lymphopenia].
The sporadic observation of pneumocystosis in patients suffering from systemic diseases led us to investigate the role of treatment-induced lymphopenia, affecting in particular CD4 cells. We report the results of a retrospective study on 16 patients in whom infectious complications were sought and correlated with the number of lymphocytes.
Service de Médecine Interne, Hôpital Avicenne, Bobigny.
C
C
Ginsburg
L
L
Guillevin
F
F
Sauvaget
F
F
Lhote
B
B
Jarrousse
H
H
Komarover
D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy / Q000209:etiology; D003520:Cyclophosphamide / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008231:Lymphopenia / Q000139:chemically induced* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange / Q000009:adverse effects*; D011241:Prednisone / Q000009:adverse effects*; D012189:Retrospective Studies; D013997:Time Factors
D003520:Cyclophosphamide; D011241:Prednisone
Maladies systémiques traitées par corticoïdes, échanges plasmatiques et cyclophosphamide: complications infectieuses et lymphopénie.