Paternity in a patient with testicular seminoma and contralateral testicular intraepithelial neoplasia.
A 32-year-old patient with unilateral beta hCG-positive seminoma and contralateral testicular intraepithelial neoplasia (TIN; so-called carcinoma-in-situ) with no metastases (clinical stage I) received one course of adjuvant carboplatin therapy. He refused further treatment of TIN in his remaining testis. His wife became pregnant by him 4 months later and delivered a healthy child at term. This case shows that patients with TIN in their remaining solitary testis are not necessarily infertile, and testes afflicted with TIN must also contain tubules that retain normal spermatogenic potential. Surveillance may be an treatment option for patients with TIN in their remaining testis in cases where there is a strong desire for paternity.
Urologische Klinik, Freie Universität Berlin, Germany.
K P
KP
Dieckmann
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V
Loy
D000328:Adult; D002278:Carcinoma in Situ / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D004407:Dysgerminoma / Q000150:complications / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D013736:Testicular Neoplasms / Q000150:complications / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery