[Autopsy case of non-invasive thymoma associated with pancytopenia and hypogammaglobulinemia].
A 57-year-old male presented with palpitations and dyspnea on exertion. Examination of the peripheral blood and bone marrow showed pancytopenia with marked red cell aplasia. Hypogammaglobulinemia was also recognized. Chest X-ray and CT showed a mass in the anterior mediastinum. A biopsy showed thymoma. Two months after admission, the patient died of sepsis secondary to worsening pancytopenia and hypogammaglobulinemia. Autopsy showed non-invasive spindle cell type thymoma and a marked decrease of hematogenous cells. Review of the literature indicates that pancytopenia associated with thymoma is resistant to all forms of treatment and its prognosis is poor.
Nomori
H
H
Department of Surgery, Saiseikai Central Hospital.
Kobayashi
R
R
Takahashi
Y
Y
Iga
R
R
Morinaga
S
S
D000361:Agammaglobulinemia / Q000150:complications*; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000150:complications*; D011379:Prognosis; D018805:Sepsis / Q000150:complications; D013945:Thymoma / Q000150:complications / Q000473:pathology*; D013953:Thymus Neoplasms / Q000150:complications / Q000473:pathology*