[Autosomal dominant polycystic kidney disease: urologic complications and results of kidney transplantation: 217 patients].
The authors report a retrospective series of 217 cases of autosomal dominant renal polycystic disease collected over a period of 30 years in the urology and nephrology departments of Nantes university hospital. They study the incidence of urological complications, observed in 87 patients (40%), consisting of calculi (15%), infection (22%, with 4 deaths), intracystic haemorrhages (3.5%) and urinary tract compression (2%). The diagnostic and therapeutic methods are presented and discussed. The results of renal transplantation are also analysed: 39 patients were transplanted, 72% retained a functioning kidney with a mean follow-up of 44.9 months (range: 12-108 months) and three patients died as a result of infectious complications. The 1-year and 3-year actuarial transplant survival rate of 92% was similar to that of renal transplantations performed for another form of renal disease. Preparation for renal transplantation remains an essential problem: the two major indications for pre-transplantation nephrectomy were the size of the kidneys and the presence of infection.
Clinique urologique, Centre hospitalier-universitaire de Nantes, Hôtel-Dieu.
O
O
Wetzel
M
M
Hormi
L
L
Le Normand
G
G
Karam
J
J
Guenel
J
J
Auvigne
J M
JM
Buzelin
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006417:Hematuria / Q000209:etiology; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications* / Q000601:surgery*; D011704:Pyelonephritis / Q000209:etiology; D012189:Retrospective Studies; D018805:Sepsis / Q000209:etiology; D015996:Survival Rate; D014545:Urinary Calculi / Q000209:etiology
La maladie polykystique rénale autosomique dominante: complications urologiques et résultats de la transplantation rénale: 217 patients.