[A case of vivax malaria with thrombocytopenia suggesting immunological mechanisms].
Recently, it has been shown that the thrombocytopenia that complicates some malarial infections is caused by immune mechanisms. We report a case of malaria associated with thrombocytopenia and increased platelet-associated IgG (PAIgG). In this case, anti-malarial therapy reduced the level of PAIgG to normal levels in association with normalization of the platelet count. This case suggests the immunological mechanisms of thrombocytopenia in malaria.
First Department of Internal Medicine, Tokyo Medical College.
M
M
Ohtaka
K
K
Ohyashiki
H
H
Iwabuchi
A
A
Iwabuchi
K Y
KY
Lin
K
K
Toyama
D000328:Adult; D001792:Blood Platelets / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D016780:Malaria, Vivax / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D008297:Male; D011803:Quinine / Q000008:administration & dosage; D013413:Sulfadoxine / Q000008:administration & dosage; D013921:Thrombocytopenia / Q000209:etiology*; D014195:Travel
D007074:Immunoglobulin G; D013413:Sulfadoxine; D011803:Quinine