Tremor and skeletal muscle tone.
Stereotactic interventions at thalamic/subthalamic levels for parkinsonian tremor give the chance to investigate the influence of the supraspinal proprioceptive loops on the tonic component of motor tasks. Studies demonstrate not only a normalization of the late stretch reflex component and a decrease of the pre-reflex stiffness in muscles contralateral to the side of the lesion, but also a reduction of low threshold motor unit firing frequency in the elbow flexors during isometric contractions. These data indicate a shift from a more tonic to a more phasic mode of innervation, which we interpret as the cause of hypotonia.
Klinikum rechts der Isar der TU München, BRD.
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D006801:Humans; D009123:Muscle Hypotonia / Q000209:etiology / Q000503:physiopathology*; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology*; D014202:Tremor / Q000209:etiology / Q000503:physiopathology*