Orally active water-soluble N,O-acyl transfer products of a beta,gamma-bishydroxyl amide containing renin inhibitor.
Hurley
T R
TR
Department of Analytical Development, Parke-Davis Pharmaceutical Research, Ann Arbor, Michigan 48106.
Colson
C E
CE
Hicks
G
G
Ryan
M J
MJ
D000284:Administration, Oral; D000577:Amides / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology; D000818:Animals; D008252:Macaca fascicularis; D008297:Male; D012995:Solubility; D013329:Structure-Activity Relationship; D000092502:Renin Inhibitors
D000577:Amides; D000092502:Renin Inhibitors