Occurrence of primary biliary cirrhosis, CREST syndrome and Sjögren's syndrome in a patient with HTLV-I-associated myelopathy.
We report the occurrence of three autoimmune diseases (primary biliary cirrhosis, CREST syndrome and Sjögren's syndrome) in a patient with HTLV-I-associated myelopathy (HAM). The patient had the depressed cell-mediated immune responses but the infiltration of CD8-T cells was found in the cerebrospinal fluid and liver. The clinical and immunological features of this case are similar to those of chronic graft-versus-host disease.
Kuroda
Y
Y
Department of Internal Medicine (Section of Neurology), Saga Medical School, Japan.
Fukuoka
M
M
Endo
C
C
Matsui
M
M
Kurohara
K
K
Kakigi
R
R
Tokunaga
O
O
D001706:Biopsy; D016827:CD8 Antigens / Q000032:analysis; D005260:Female; D015490:HTLV-I Infections / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000276:immunology / Q000473:pathology; D008214:Lymphocytes / Q000276:immunology*; D008875:Middle Aged; D011859:Radiography; D012594:Scleroderma, Localized / Q000150:complications* / Q000276:immunology / Q000473:pathology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000276:immunology / Q000473:pathology; D013116:Spinal Cord / Q000000981:diagnostic imaging / Q000473:pathology*; D016176:T-Lymphocyte Subsets / Q000276:immunology / Q000473:pathology
D016827:CD8 Antigens