[Topical treatment with oxybutynin chloride in neurogenic incontinence].
Intravesical oxybutynin chloride was administered to 12 children with neurogenic bladder and incontinence who had unacceptable side effects. Urodynamic studies showed hyperreflexia was eliminated or improvement in 100% of them and low compliance was improved (88%), with a mean increase in bladder volume to 123% and a mean decrease of filling pressure to 24 cm H2O. Six patients became completely dry (50%), 4 continent period was increased and 2 did not improve. No systemic effects were observed.
Departamento de Cirugía Pediátrica, Unidad de Urología, Hospital Infantil La Paz, Madrid.
P
P
López Pereira
M J
MJ
Martínez
R
R
Muguerza
E
E
Jaureguizar
D000287:Administration, Topical; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000008:administration & dosage* / Q000627:therapeutic use; D010276:Parasympatholytics / Q000008:administration & dosage* / Q000627:therapeutic use; D001750:Urinary Bladder, Neurogenic / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D014549:Urinary Incontinence / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D014563:Urodynamics
D008333:Mandelic Acids; D010276:Parasympatholytics; C005419:oxybutynin
Tratamiento tópico con cloruro de oxibutinina en la incontinencia de causa neurógena.