[Current status of transfusion-transmitted infection].
Recently transfusion-transmitted infections (TTI) have been decreased remarkably. Especially nonA, nonB posttransfusion hepatitis (PTH) has reduced to one third by introducing anti-HCV (C100-3) antibody screening. HCV-PTH will be lowered more with screening by the 2nd generation reagent of HCV. None of cases with HIV infection by transfusion has been reported since introduction of anti-HIV antibody screening, but we have to watch out it, due to rapid increase of heterosexual infection of HIV during this one year in Japan. Voluntary blood donors should warrant blood safety by their own responsibility. We have no cases with malaria by transfusion for these several years. There are no reported cases with Chagas' disease in Japan, but increase of international immigrations will be potential to introduce these infections by transfusion into Japan. Recently TTI by bacteria-contaminated blood have been very rare owing to technical improvement of blood-drawing. However, platelet concentrates stored at 22 degrees C for 3-5 days and red cell products stored at 4 degrees C for 35-42 days have presented new problems concerning bacterial contamination. We have to consider these problems concerning bacterial contamination.
Shimizu
M
M
Department of Transfusion Medicine, Tokyo Women's Medical College.
D001782:Blood Donors; D001793:Blood Preservation / Q000592:standards; D015658:HIV Infections / Q000517:prevention & control / Q000635:transmission; D006526:Hepatitis C / Q000517:prevention & control / Q000635:transmission*; D006801:Humans; D065227:Transfusion Reaction