[The relationship between oxygen consumption and the the rate of rewarming during extracorporeal circulation with induced hypothermia].
This study was performed to investigate the relation between total oxygen consumption (VO2) and the velocity of reheating in patients undergoing cardiopulmonary bypass with hypothermia. A total of 17 males undergoing this procedure were studied prospectively (mean age: 63 years, range: 52-72); during surgery they were cooled at 28 degrees C whole-body temperature. Before rewarming, patients were divided at random in two groups. Group A (n = 8) was reheated between 10 and 25 minutes, and group B (n = 9) between 26 and 50 minutes. In group A, VO2 expressed in ml.min-1 x m-2 increased from 76.6 +/- 6.99 at 28 degrees C until 100.0 +/- 6.72 at 34 degrees C; in group B increased from 68.4 +/- 4.55 until 129.1 +/- 4.73 at similar temperatures (analysis of variance: p < 0.01 at 28 degrees C). A greater VO2 in group B could indicate that slow rewarming would cause an even distribution of temperature with enough time for tissues to rid of their oxygen debt.
Departamento de Cirugía Cardiovascular, Fundación H. Pombo de Rodríguez, Academia Nacional de Medicina, Buenos Aires, Argentina.
R A
RA
Borracci
J
J
Baldi
D000368:Aged; D000704:Analysis of Variance; D001831:Body Temperature; D004311:Double-Blind Method; D005112:Extracorporeal Circulation / Q000706:statistics & numerical data; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D007036:Hypothermia, Induced / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization / Q000706:statistics & numerical data; D010101:Oxygen Consumption; D011446:Prospective Studies; D013997:Time Factors
Relación entre consumo de oxígeno y velocidad de recalentamiento durante la circulación extracórporea con hipotermia inducida.