Local medical treatment of interstitial pregnancy after in-vitro fertilization and embryo transfer (IVF-ET): two case reports.
Two cases of interstitial pregnancy (one singleton, one heterotopic twins) were confirmed 31 and 34 days after in-vitro fertilization. Serum human chorionic gonadotrophin concentrations were 35,000 and 86,000 mlU/ml, respectively. They were treated conservatively with transvaginal ultrasonically guided intra-ovular injection of either methotrexate in the singleton pregnancy, or potassium chloride into the ectopic sac of the heterotopic twins. No complications were observed. The intra-uterine pregnancy continued and the patient delivered a 3350 g healthy baby at 39 weeks.
Centre de PMA Baudelocque St-Vincent de Paul, Paris, France.
J A
JA
Pérez
M M
MM
Sadek
M
M
Savale
P
P
Boyer
J R
JR
Zorn
D000032:Abortion, Therapeutic / Q000379:methods*; D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood*; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007267:Injections; D008727:Methotrexate / Q000008:administration & dosage; D011189:Potassium Chloride / Q000008:administration & dosage; D011247:Pregnancy; D011256:Pregnancy Outcome; D011271:Pregnancy, Ectopic / Q000097:blood / Q000000981:diagnostic imaging / Q000628:therapy*; D016216:Ultrasonography, Prenatal
D006063:Chorionic Gonadotropin; D011189:Potassium Chloride; D008727:Methotrexate