The effect of amoxycillin versus penicillin V in the treatment of acutely abscessed primary teeth.
A clinical study was carried out to compare the efficacy of a short course, high dose amoxycillin versus a conventional penicillin regimen in the treatment of acute abscessed primary teeth. In a blind way children were assigned to either group A (amoxycillin) or group B (penicillin). The efficacy of the antibiotics was assessed using the clinical parameters of pain, swelling, tenderness, mobility and lymphadenitis. The results showed a general trend of less swelling in patients in group A as compared with patients in group B. This was significant at days 1 and 7 for the operators assessment (Mann Whitney U test; z = 2.48 and z = 2.12). More teeth in group A were considered suitable for first stage pulpectomy by day 7 (c2 test; P 0.037 pounds). A short course, high dose amoxycillin regimen proved as efficacious as a conventional penicillin regimen.
Division of Child Dental Health, Leeds Dental Institute.
S A
SA
Paterson
M E
ME
Curzon
D000658:Amoxicillin / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D010147:Pain Measurement; D010349:Patient Compliance; D010404:Penicillin V / Q000008:administration & dosage / Q000627:therapeutic use*; D010482:Periapical Abscess / Q000188:drug therapy*; D011670:Pulpectomy; D014094:Tooth, Deciduous
D000658:Amoxicillin; D010404:Penicillin V