[Lipid peroxidation processes and activity of brain succinate dehydrogenase in experimental craniocerebral trauma].
A statistically significant decrease in the activity of succinate dehydrogenase (SDH) was found in the rabbit brain after craniocerebral injury. The decrease in the activity of brain SDH was not shown to result from "competitive inhibition" by malonate accumulated after activation of lipid peroxidation. The activity of brain SDH was normalized by directed modification of the function of the central nervous system via administration of phenamine (amphetamine) into the injured animals.
Demchuk
M L
ML
Medvedev
A E
AE
Promyslov
M Sh
MSh
Gorkin
V Z
VZ
D000818:Animals; D001921:Brain / Q000201:enzymology*; D001930:Brain Injuries / Q000201:enzymology*; D007700:Kinetics; D015227:Lipid Peroxidation; D008297:Male; D008314:Malonates / Q000378:metabolism; D011817:Rabbits; D013385:Succinate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*
D008314:Malonates; C030290:malonic acid; D013385:Succinate Dehydrogenase
Protsessy perekisnogo okisleniia lipidov i aktivnost' suktsinatdegidrogenazy mozga pri cherepno-mozgovoĭ travme v éksperimente.