Potential use of IgA protease therapy in IgA myeloma patients.
Multiple myeloma is generally not cured with conventional cytotoxic chemotherapy. Biologic agents and bone marrow transplantation have been among the newer avenues explored to increase the cure rate. It is suggested that IgA proteases too may be of value in the treatment of IgA myeloma.
Lee Streich Flow Cytometry Laboratory, Brookdale Hospital Medical Center, Brooklyn, NY 11212.
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Nusbaum
D000936:Antigen-Antibody Complex / Q000097:blood; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000378:metabolism*; D008954:Models, Biological; D009101:Multiple Myeloma / Q000097:blood / Q000276:immunology / Q000628:therapy*; D010447:Peptide Hydrolases / Q000627:therapeutic use*; D012697:Serine Endopeptidases
D000936:Antigen-Antibody Complex; D007070:Immunoglobulin A; D010447:Peptide Hydrolases; D012697:Serine Endopeptidases; C021433:IgA-specific serine endopeptidase