In situ hybridization localizes the human OTF3 to chromosome 6p21.3-->p22 and OTF3L to 12p13.
Otf-3 (Octamer-binding transcription factor 3) is an octamer binding protein encoded by the murine gene Otf-3. Otf-3 belongs to a multigenic family and maps to the mouse Chromosome 17 between the Q and T regions within the major histocompatibility complex (MHC). We report the mapping of the human homologue: OTF3, to human chromosome 6p21.3-->p22 within or close to the human MHC class I region. Furthermore, one OTF3-like copy (OTF3L) is localized to 12p13.
LIGHT INSERM CNRS, Toulouse, France.
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Guillaudeux
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Mattei
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Depetris
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Le Bouteiller
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Pontarotti
D001399:Azure Stains; D002871:Chromosome Banding; D002874:Chromosome Mapping / Q000379:methods; D002881:Chromosomes, Human, Pair 12; D002896:Chromosomes, Human, Pair 6; D004268:DNA-Binding Proteins / Q000235:genetics*; D005805:Genes, MHC Class I; D006801:Humans; D017403:In Situ Hybridization; D050814:Octamer Transcription Factor-3; D014157:Transcription Factors / Q000235:genetics*
D001399:Azure Stains; D004268:DNA-Binding Proteins; D050814:Octamer Transcription Factor-3; C494173:POU5F1 protein, human; D014157:Transcription Factors