A comparison of diclofenac with and without single-dose intravenous steroid to prevent postoperative pain after third molar removal.
The efficacy of 40 mg of methylprednisolone given intravenously before operation in combination with orally administered rapid-release and sustained-release diclofenac preparations in preventing postoperative pain after third molar removal was studied. The administration of methylprednisolone and diclofenac resulted in greater pain relief than did administration of diclofenac alone.
University of Helsinki, Finland.
T
T
Hyrkäs
P
P
Ylipaavalniemi
V J
VJ
Oikarinen
I
I
Paakkari
D000284:Administration, Oral; D000328:Adult; D003692:Delayed-Action Preparations; D004008:Diclofenac / Q000008:administration & dosage* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D008964:Molar, Third / Q000601:surgery*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011292:Premedication; D014081:Tooth Extraction
D003692:Delayed-Action Preparations; D004008:Diclofenac; D008775:Methylprednisolone