The benefits of clomipramine-fluoxetine combination in obsessive compulsive disorder.
We report the benefits of clomipramine-fluoxetine combination in four cases of severe obsessive compulsive disorder. In two cases, the combination was effective when either drug used singly was ineffective. In the other two cases, fluoxetine adjunct produced benefits with no additional side effects.
Browne
M
M
Out-Patient Department, Queensway Carleton Hospital, Ottawa, Ontario.
Horn
E
E
Jones
T T
TT
D000328:Adult; D002997:Clomipramine / Q000008:administration & dosage* / Q000009:adverse effects; D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000523:psychology; D012008:Recurrence
D005473:Fluoxetine; D002997:Clomipramine