Mycophenolate mofetil and brequinar sodium: new immunosuppressive agents.
Our results demonstrate the potent immunosuppressive activity of combination MM and BQR therapy to prolong allograft survival. In addition, MM may provide a highly effective therapy for the prevention of chronic rejection.
Department of Surgery, University of Wisconsin School of Medicine, Madison.
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Hullett
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Sollinger
D000818:Animals; D001713:Biphenyl Compounds / Q000494:pharmacology*; D006085:Graft Survival / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D011798:Quinaldines
D001713:Biphenyl Compounds; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid; C046943:brequinar; D011798:Quinaldines