Unilateral linear lichenoid eruption after bone marrow transplantation: an unmasking of tolerance to an abnormal keratinocyte clone?
Chronic cutaneous graft-versus-host disease may appear clinically as a lichenoid eruption. We describe a 26-year-old man who developed a unilateral linear lichenoid eruption 7 months after allogeneic bone marrow transplantation. We believe this represents an unusual form of localized, chronic graft-versus-host disease. The possible relationship to viral infection or cellular mosaicism and the clinical, histologic, and immunologic similarities to idiopathic lichen planus are discussed.
Division of Dermatology, University of Florida College of Medicine.
B
B
Beers
R S
RS
Kalish
V N
VN
Kaye
M V
MV
Dahl
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002999:Clone Cells; D006086:Graft vs Host Disease / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007108:Immune Tolerance; D015603:Keratinocytes / Q000276:immunology / Q000473:pathology; D007642:Keratosis / Q000473:pathology; D017512:Lichenoid Eruptions / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D008297:Male