The Salmonella typhimurium uracil-sensitive mutation use is in argU and encodes a minor arginine tRNA.
The use gene of Salmonella typhimurium was previously identified by a mutation conferring sensitivity to uracil in glucose minimal medium. The use gene was cloned and identified as an allele of argU encoding a tRNA for a minor arginine codon (CGG). The uracil-sensitive phenotype was shown to result from a base substitution in the anticodon stem of this tRNA.
Lu
C D
CD
Biology Department, Georgia State University, Atlanta 30303.
Abdelal
A T
AT
D000926:Anticodon; D001483:Base Sequence; D003001:Cloning, Molecular; D017353:Gene Deletion; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D009154:Mutation; D010641:Phenotype; D012347:RNA, Transfer, Arg / Q000235:genetics*; D015183:Restriction Mapping; D012486:Salmonella typhimurium / Q000235:genetics*; D014498:Uracil / Q000378:metabolism
D000926:Anticodon; D012347:RNA, Transfer, Arg; D014498:Uracil