Antimicrobial activity determined in strains of Bacillus circulans cluster.
Wild-type strains of the genus Bacillus were screened for antimicrobial activity. Two strains exhibited antimicrobial activity against Micrococcus luteus and were identified as Bacillus polymyxa MIR-23 and Bacillus circulans MIR-13. Bacillus polymyxa MIR-23 was active against Escherichia coli, Pseudomonas aeruginosa and Aspergillus niger, whereas Bacillus circulans MIR-13 did not show activity against these microorganisms. Bacillus subtilis ATCC 6633 and B. polymyxa ATCC 10401 were used as standard antibiotic-producer strain and showed different antimicrobial profiles and yields from B. polymyxa MIR-23. The different antimicrobial profile of the two selected strains could possibly be used as a taxonomic marker.
Cátedra de Farmacología, Facultad de Odontología, Universidad de Buenos Aires, Argentina.
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D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000494:pharmacology; D001234:Aspergillus niger / Q000187:drug effects; D001407:Bacillus / Q000378:metabolism*; D004353:Drug Evaluation, Preclinical; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D016982:Micrococcus luteus / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects
D000900:Anti-Bacterial Agents