Peculiar facial erythematosquamous lesions in two siblings with cyclical summer improvement and winter relapse: a variant of keratosis lichenoides chronica?
A 7-year-old girl had erythematous hyperkeratotic papules and plaques that improved in summer and recurred in winter since the age of 4 months. She had had irregular, ridge-like erythematosquamous lesions on the arms with the same seasonal variation. The lesions on the arms improved with age. Light and electron microscopic examination showed marked degeneration of keratinocytes and prominent apoptosis. Her older brother had a similar but milder dermatosis. We believe these cases may represent a variant of keratosis lichenoides chronica.
Department of Dermatology, Okayama University Medical School, Japan.
J
J
Arata
A
A
Seno
J
J
Tada
E
E
Wada
H
H
Tamaki
M
M
Tamaki
D017209:Apoptosis; D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D003937:Diagnosis, Differential; D004817:Epidermis / Q000473:pathology; D004890:Erythema / Q000235:genetics* / Q000473:pathology; D005110:Extracellular Space; D005148:Facial Dermatoses / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D015603:Keratinocytes / Q000473:pathology; D007642:Keratosis / Q000235:genetics* / Q000473:pathology; D017512:Lichenoid Eruptions / Q000235:genetics* / Q000473:pathology; D008297:Male; D012008:Recurrence; D012621:Seasons