Transcutaneous oxygen monitoring for predicting skin viability in dogs.
Transcutaneous oxygen (PO2-TC) monitoring is commonly used in human medicine for evaluating skin viability. The application of transcutaneous monitoring for evaluating skin viability in dogs was investigated. The changes in PO2-TC values were measured from 16 avascular skin flaps created along the lateral hemithoraces of 4 dogs. Transcutaneous oxygen values were serially recorded from the vascular base and avascular apex of each flap for 12 hours after surgery. A single transcutaneous measurement was obtained from each flap base and apex 24 hours after surgery. Serial arterial blood gas analyses were obtained to compare central oxygen values with PO2-TC values. Full-thickness skin biopsy specimens were harvested from the base and apex of each flap 24 hours after surgery. The flaps were observed for 4 days and then excised for histologic examination. A subjective grading scale was used to assess histologic changes. Throughout the 12-hour period and at 24 hours, a statistically significant difference was found between the PO2-TC values for apices and bases of the flaps. The mean PO2-TC for all bases was 90.9 mm of Hg +/- 3.3 SEM, and the mean PO2-TC for all apices was 21.2 mm of Hg +/- 1.8 SEM. The mean regional perfusion index (apex PO2-TC/base PO2-TC) was 0.23 +/- 0.02. The subjective numbers assigned to the biopsy specimens were statistically evaluated by using a paired Student's t test and a Wilcoxon signed-rank test. A significant difference was found between the numbers for the collective bases and apices with both tests.(ABSTRACT TRUNCATED AT 250 WORDS)
Rochat
M C
MC
Department of Veterinary Medicine, College of Veterinary Medicine, University of Missouri, Columbia 65211.
Pope
E R
ER
Payne
J T
JT
Pace
L W
LW
Wagner-Mann
C C
CC
D000818:Animals; D001706:Biopsy; D001784:Blood Gas Analysis / Q000295:instrumentation / Q000379:methods / Q000662:veterinary; D004285:Dogs / Q000502:physiology*; D005260:Female; D007249:Inflammation; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods / Q000662:veterinary; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D012867:Skin / Q000098:blood supply / Q000166:cytology; D012879:Skin Physiological Phenomena; D013524:Surgical Flaps / Q000662:veterinary*
D010100:Oxygen