Heparin-induced thrombocytopenia in children.
Two children aged 3 months and 14 years developed heparin-induced thrombocytopenia whilst receiving heparin. The clinical course was complicated by renal vein thrombosis in the 3-month-old infant and subcutaneous haemorrhage requiring resuscitation in the 14-year-old child. Anticoagulant therapy was discontinued immediately in the 3-month-old child. In the 14-year-old child, because of the need for continued anticoagulation therapy, low molecular weight heparin was used until warfarin could be substituted.
Department of Paediatrics, Guy's Hospital, London, UK.
I A
IA
Murdoch
R M
RM
Beattie
D M
DM
Silver
D000293:Adolescent; D005260:Female; D006493:Heparin / Q000009:adverse effects* / Q000494:pharmacology; D006801:Humans; D007223:Infant; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects; D013921:Thrombocytopenia / Q000139:chemically induced*
D006493:Heparin