[Radiation therapy in the prevention of periarticular, heterotopic ossification following implantation of a total hip endoprosthesis].
From June 1988 to January 1991 the efficacy of a low-dose (5 x 2 Gy) versus a high-dose (10 x 2 Gy, resp. 5 x 3,5 Gy) prophylactic postoperative radiotherapy was assessed in a prospective randomized trial. 60 patients at the highest risk for formation of heterotopic ossification (HO) were included in this study, i.e. patients that presented already HO in the ipsi- or contralateral hip at the time of surgery. After both irradiation regimen the incidence and severity of HO was significantly less than without prophylaxis; there was no significant difference (regarding the severity of HO, the hip score (16) and the hip mobility) between the two regimen.
Goldmann
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AR
Orthopädische Klinik und Poliklinik, Friedrich-Alexander Universität Erlangen-Nürnberg.
Seegenschmiedt
M
M
Andreas
P
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Hohmann
D
D
Sauer
R
R
Beck
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H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000517:prevention & control / Q000532:radiotherapy*; D011183:Postoperative Complications / Q000517:prevention & control; D011446:Prospective Studies; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D012307:Risk Factors
D003037:Cobalt Radioisotopes
Strahlentherapie zur Prophylaxe von periartikulären, heterotopen Ossifikationen nach Implantation von Hüfttotalendoprothesen.