Prevalence of cervical pathogens in women with and without inflammatory changes on smear testing.
OBJECTIVE
To assess correlation between nonspecific cervicitis, inflammation, or exudate on cervical smears tests and confirmed presence of known cervical pathogens.


METHODS
Investigation of women attending a family practice clinic for smear test by microbiological screening for Chlamydia trachomatis, Mycoplasma hominis, Ureaplasma urealyticum, Trichomonas vaginalis, Candida species, group B streptococcus, Gardnerella vaginalis, and Neisseria gonorrhoeae.


METHODS
Family practice teaching clinic in a university hospital.


METHODS
411 women presenting for a smear test.


METHODS
Prevalence of genital infections associated with presence or absence of inflammatory changes on cervical smear.


RESULTS
Of the 132 women with inflammatory changes on cervical smear, 64 (48%) had positive cultures. Of the 248 without inflammatory changes, 117 (47%) had positive cultures. Subgroup analysis on individual organisms also showed no significant difference between the two groups.


CONCLUSIONS
Reports of inflammatory changes on cervical smear testing are a poor indicator of infection.
Memorial University of Newfoundland, St John's, Canada.
W L
WL
Parsons
M
M
Godwin
C
C
Robbins
R
R
Butler
D000328:Adult; D002181:Candidiasis, Vulvovaginal / Q000382:microbiology; D002584:Cervix Uteri / Q000382:microbiology*; D002690:Chlamydia Infections / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D013292:Streptococcus agalactiae / Q000302:isolation & purification; D002575:Uterine Cervicitis / Q000382:microbiology*; D014626:Vaginal Smears