[C-reactive protein in bacterial meningitis in adults].
In order to assess the benefits of serial assays of C-reactive protein in the course of bacterial meningitis in adults, daily blood samples were taken for CRP measurement during 10 days in 21 consecutive patients (mean age: 24 +/- 8 years) hospitalized for bacterial meningitis principally due to Neisseria meningitidis (n = 15). The highest CRP level (178 +/- 38 mg/l) was present on admission, followed by a regular decrease occurring in uncomplicated meningitis until normal level was achieved on day 9. The CRP kinetics was not influenced by the type of causative micro-organism. This study shows that CRP kinetics in adults is similar to that reported in children. The benefit of CRP assays in optimizing the duration of antibiotic treatment of meningitis needs to be more carefully assessed.
Nouira
S
S
Service de Réanimation polyvalente, CHU Fattouma-Bourguiba, Monastir, Tunisie.
Elatrous
S
S
Mustapha
R
R
Abroug
S
S
Bchir
A
A
Belghith
M
M
Boujdaria
R
R
Jaafoura
M
M
Najjar
M F
MF
Abroug
F
F
D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D001168:Arthritis / Q000097:blood / Q000209:etiology; D002097:C-Reactive Protein / Q000032:analysis*; D002439:Cefotaxime / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000097:blood* / Q000134:cerebrospinal fluid / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged; D010068:Oxacillin / Q000627:therapeutic use; D010400:Penicillin G / Q000627:therapeutic use; D011446:Prospective Studies
D000667:Ampicillin; D002097:C-Reactive Protein; D002439:Cefotaxime; D010400:Penicillin G; D010068:Oxacillin
La protéine c-réactive dans les méningites bactériennes de l'adulte.