Zirconium granuloma resulting from an aluminum zirconium complex: a previously unrecognized agent in the development of hypersensitivity granulomas.
Zirconium compounds have been associated with the development of hypersensitivity granulomas. However, aluminum zirconium complexes have not previously been shown to induce sensitization. We present the clinical and histologic findings of a case in which a patient developed an acute hypersensitivity reaction to an aluminum zirconium complex.
Skelton
H G
HG
Department of Dermatopathology, Armed Forces Institute of Pathology, Walter Reed Institute of Research, George Washington University.
Smith
K J
KJ
Johnson
F B
FB
Cooper
C R
CR
Tyler
W F
WF
Lupton
G P
GP
D000328:Adult; D000535:Aluminum / Q000009:adverse effects*; D001365:Axilla; D003836:Deodorants / Q000009:adverse effects; D005260:Female; D005355:Fibrosis; D005990:Glycerol / Q000009:adverse effects / Q000031:analogs & derivatives*; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology* / Q000473:pathology; D009336:Necrosis; D009942:Organometallic Compounds / Q000009:adverse effects*; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology; D015040:Zirconium / Q000009:adverse effects*
D003836:Deodorants; D009942:Organometallic Compounds; C081216:aluminum zirconium tetrachlorohydrexglycerin; D015040:Zirconium; D000535:Aluminum; D005990:Glycerol