A new antibiotic, structurally related to leptomycin A, flattens the morphology of v-ras(ts) NRK cells.
Hosokawa
N
N
Institute of Microbial Chemistry, Tokyo, Japan.
Iinuma
H
H
Naganawa
H
H
Hamada
M
M
Takeuchi
T
T
Itoh
T
T
Hori
M
M
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D002460:Cell Line; D005231:Fatty Acids, Unsaturated / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011905:Genes, ras / Q000187:drug effects*; D007668:Kidney / Q000166:cytology* / Q000187:drug effects; D007928:Lethal Dose 50; D051379:Mice; D011714:Pyrans / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D051381:Rats; D013302:Streptomyces / Q000737:chemistry*
D000903:Antibiotics, Antineoplastic; D005231:Fatty Acids, Unsaturated; D011714:Pyrans; C081419:reductoleptomycin A