Post-orchiectomy management in stage I testicular seminoma: elective irradiation or surveillance?
Fifty-six patients with stage I testicular seminoma were treated at this institute between January 1982 and December 1988. Post-orchiectomy elective radiotherapy to ipsilateral iliac-inguinal and para-aortic lymph nodes was delivered in 54 cases. An overall 3 year survival rate of 96% was observed in this series. Four patients (7%) relapsed (one junctional recurrence in iliac node region, two mediastinal/hilar nodes and one skeletal metastasis). Salvage chemotherapy proved successful in two out of three cases with nodal relapse. No dose limiting acute or late radiation related complications were noticed. No definite correlation was found between the patients who relapsed and various known adverse prognostic factors. We recommend elective irradiation of the draining lymph nodes in stage I seminoma, particularly at centres where surveillance is not feasible.
Department of Radiotherapy, Gujarat Cancer & Research Institute, Ahmedabad, India.
S
S
Singhal
S
S
Dixit
R K
RK
Vyas
J P
JP
Neema
R R
RR
Murthy
H A
HA
Baboo
D000328:Adult; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000532:radiotherapy* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000532:radiotherapy* / Q000601:surgery*