Synergistic activity of the triple combination: cyclosporine, rapamycin, and brequinar.
Stepkowski
S M
SM
Department of Surgery, University of Texas Medical School, Houston 77030.
Kahan
B D
BD
D000284:Administration, Oral; D000818:Animals; D001713:Biphenyl Compounds / Q000494:pharmacology*; D016572:Cyclosporine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006085:Graft Survival / Q000187:drug effects*; D016027:Heart Transplantation; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D011090:Polyenes / Q000494:pharmacology*; D051381:Rats; D011920:Rats, Inbred WF; D020123:Sirolimus; D014184:Transplantation, Homologous; D011798:Quinaldines
D001713:Biphenyl Compounds; D016572:Cyclosporine; D007166:Immunosuppressive Agents; D011090:Polyenes; D020123:Sirolimus; C046943:brequinar; D011798:Quinaldines