[Storage of thrombocyte concentrates: quality control by in vitro bleeding test].
BACKGROUND
The increasing demand for single-donor platelet concentrates necessitates the storage of these blood products prior to transfusion. Quality control of these platelets, however, is still a problem. Most of the available techniques are time-consuming and require sophisticated equipment and specifically trained personnel. The present paper describes a new method for quality control of stored platelet concentrates.


METHODS
Single-donor platelet concentrates were stored for 7 days; daily aliquots were taken and the in vitro bleeding time (Thrombostat 4000) and platelet aggregation (aggregometer) were determined.


RESULTS
The in vitro bleeding test can be handled simply and fast. The results are comparable with those of platelet aggregation tests.


CONCLUSIONS
The in vitro bleeding test provides a good alternative to the conventional methods commonly used for quality control of platelet concentrates.
Tranfusionzentrum (Med. Klinik III) Klinikum Grosshadern, Universität München.
A
A
Glaser
M
M
Böck
G
G
Rüschemeyer
C
C
Salat
M U
MU
Heim
E
E
Hiller
W
W
Mempel
D001760:Bleeding Time; D016913:Blood Component Transfusion; D001793:Blood Preservation / Q000379:methods*; D006801:Humans; D066298:In Vitro Techniques; D010974:Platelet Aggregation / Q000502:physiology; D011786:Quality Control; D012016:Reference Values
Lagerung von Thrombozytenkonzentraten: Qualitätskontrolle durch In-vitro-Blutungstest.