Continuous subarachnoid infusion of local anaesthetic.
We observed the sensory, motor and cardiovascular changes occurring during subarachnoid infusion of bupivacaine 0.125% at 15 ml.h-1 in six patients. After 1 h, motor block and lower sensory levels were consistent and predictable but upper sensory levels were variable. There was a moderate decrease in systolic blood pressure. Regular assessments of motor block are more likely to detect accidental subarachnoid infusion than assessments of upper sensory level or measurements of blood pressure.
Department of Anaesthetics, Royal Infirmary, Edinburgh.
C P
CP
Morton
P J
PJ
Armstrong
J H
JH
McClure
D000368:Aged; D000369:Aged, 80 and over; D000775:Anesthesia, Spinal / Q000009:adverse effects*; D001794:Blood Pressure / Q000187:drug effects; D002045:Bupivacaine / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000187:drug effects; D009407:Nerve Block; D009475:Neurons, Afferent / Q000187:drug effects; D011674:Pulse / Q000187:drug effects; D013997:Time Factors
D002045:Bupivacaine