Cytologic diagnosis of metastatic malignant melanoma of the lung in sputum and bronchial washings. A case report.
A 60-year-old woman with a fever, productive cough, anorexia, weight loss and past history of malignant melanoma of the finger proved to have metastatic melanoma in both lungs on cytologic study of sputum and bronchial washings. The literature in English over 40 years (1952-1992) gives only a few hints about the value of cytologic diagnosis of metastatic malignant melanoma of the lung. Cytologic features include a variable amount of melanin pigment, isolated or loosely cohesive groups of round to oval cells with eccentric nuclei, regular nuclear outline, anisocytosis, binucleation and multinucleation, fine chromatin pattern and prominent nucleoli.
Khoddami
M
M
Department of Pathology, Faghihi Hospital, Shiraz University of Medical Sciences, Medical School, Iran.
D001992:Bronchoalveolar Lavage Fluid / Q000473:pathology*; D002466:Cell Nucleolus / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary*; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology* / Q000648:ultrastructure; D008875:Middle Aged; D013183:Sputum / Q000166:cytology*
D002843:Chromatin