Mycophenolic acid and brequinar, inhibitors of purine and pyrimidine synthesis, block the glycosylation of adhesion molecules.
Allison
A C
AC
Syntex Discovery Research, Palo Alto, CA 94002.
Kowalski
W J
WJ
Muller
C J
CJ
Waters
R V
RV
Eugui
E M
EM
D000963:Antimetabolites / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000494:pharmacology*; D015815:Cell Adhesion Molecules / Q000378:metabolism*; D006031:Glycosylation / Q000187:drug effects; D006801:Humans; D009173:Mycophenolic Acid / Q000494:pharmacology*; D011687:Purines / Q000378:metabolism*; D011743:Pyrimidines / Q000096:biosynthesis*; D011798:Quinaldines
D000963:Antimetabolites; D001713:Biphenyl Compounds; D015815:Cell Adhesion Molecules; D009173:Mycophenolic Acid; D011687:Purines; D011743:Pyrimidines; C046943:brequinar; D011798:Quinaldines