Common bile duct obstruction due to intraluminal metastatic melanoma.
Although metastatic melanoma is renowned for its propensity to spread to a wide range of sites, symptomatic metastases within the biliary tree are very rare. A patient with a past history of melanoma who presented with obstructive jaundice and in whom computerized tomography (CT) scanning revealed a spherical filling defect 1 cm in diameter at the lower end of the common bile duct is reported. The obstructing lesion was thought likely to be a gallstone. However, on surgical exploration it was found to be a polypoid melanoma metastasis, freely mobile within the lumen of the lower duct but attached to its wall by a thin stalk. There was no evidence of metastatic melanoma elsewhere in the abdomen. The tumour was removed without difficulty, completely relieving the obstructive jaundice. The patient remains well 14 months later, with no evidence of recurrent visceral melanoma.
Sydney Melanoma Unit, Royal Prince Alfred Hospital, New South Wales, Australia.
J F
JF
Thompson
M N
MN
Mathur
A S
AS
Coates
D000328:Adult; D002769:Cholelithiasis / Q000175:diagnosis; D002779:Cholestasis / Q000209:etiology*; D003138:Common Bile Duct Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications / Q000175:diagnosis / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology