Morphological recognition of viral heart disease.
A large number of endomyocardial biopsies have been analysed from 1.978 patients clinically diagnosed as suffering from dilated cardiomyopathy. In 1.125 patients non-specific changes of a dilated, hypertrophied myocardium were found consistent with a clinical diagnosis of dilated cardiomyopathy. The most interesting group consisted of 676 patients among which 549 cases showed clear evidence of myocarditis. The so-called "Dallas Criteria" have been described in detail and categorised into acute, active, on-going, resolving (healing) and resolved (healed) phases. Categorization is important for therapeutic reasons. Morphological analysis performs the bases upon which other investigations can be undertaken.
Olsen
E G
EG
Department of Histopathology (Cardiovascular Disease), Royal Brompton National Heart and Lung Hospital, London, England.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D006801:Humans; D015994:Incidence; D007223:Infant; D008875:Middle Aged; D009205:Myocarditis / Q000453:epidemiology / Q000473:pathology*