[Hepato-cholangiocarcinoma with diffuse metastases and hypercalcemia].
The combined hepatocellular-cholangiocarcinoma (C-HCC) is a very uncommon neoplasm, its diagnosis is difficult and its course is usually very rapid. We report the case of a patient with CHCC type II or transitional tumor, which shows two cellular types in certain zones. Our patient had tumoral hypercalcemia as well, which was very difficult to control. There was a metastatic spread with cholangiolar features almost from the beginning, that made impossible any sort of therapy. It seems that dissemination followed lymphatic pathways.
Servicio de Aparato Digestivo, Hospital General Universitario Gregorio Marañón, Madrid.
F
F
Pérez Roldán
L
L
Carretero
A
A
Aguirre
R
R
Bañares
M
M
Casado
E
E
Cos
G
G
Clemente
D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D018281:Cholangiocarcinoma / Q000473:pathology*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology*
Hepatocolangiocarcinoma con metástasis difusas e hipercalcemia.