Does the transferrin C2 frequency depend on age?
In a previous study Beckman and Beckman [Hum Hered 1986;36:254-255] reported a decrease in the Tf C2 frequency with age, from 0.173 in newborns to 0.099 in 70-year-old healthy individuals. The authors suggested a selective disadvantage for Tf C2. In a population from Leipzig (FRG) older people have the highest C2 gene frequency (0.1701 vs. 0.1629 in children < 5 years). The differences are not significant. A dependency of C2 frequency on age seems to remain in question.
Department of Legal Medicine, University of Münster, FRG.
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Du Chesne
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D000483:Alleles; D002648:Child; D002675:Child, Preschool; D005787:Gene Frequency; D006801:Humans; D008875:Middle Aged; D014168:Transferrin / Q000235:genetics* / Q000502:physiology
D014168:Transferrin