Hypertonic saline solution: an effective wound dressing solution.
In search of a cheaper and effective dressing solution for ulcers, 53 patients presenting with various types of ulcers at the University of Port Harcourt Teaching Hospital were treated with different strengths hypertonic saline 0.3, 0.9, 1.2, 1.5, 2 and 3 osmoles. The ages of the ulcers were between 3 months and 3 years. Optimal results were obtained with solution of 1.5 mmols and above. Desloughing occurred within 2 weeks and granulation was fast and good enough for skin grafting where necessary. Healing was faster in other ulcers that were not due for grafting.
Department of Surgery, University of Port Harcourt Teaching Hospital, Nigeria.
E D
ED
Mangete
K S
KS
West
C D
CD
Blankson
D000279:Administration, Cutaneous; D006801:Humans; D009994:Osmolar Concentration; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D016038:Skin Transplantation; D012883:Skin Ulcer / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D007507:Therapeutic Irrigation; D014945:Wound Healing
D012462:Saline Solution, Hypertonic