A-bomb survivors: further evidence of late effects of early deaths.
Reanalysis of A-bomb survivor data has shown the following: a) in the high-dose (> 1 Gy) subgroups of the life span study cohort of 5-y survivors, there is a significant deficit of individuals who were < 10 y or > 50 y at the time of the bomb; and b) in the cohort on in utero children, there is a significant deficit of individuals who were < 8 wk of fetal age when exposed. This paper discusses how this selection bias has affected the perception of three effects of A-bomb radiation: marrow damage, carcinogenesis, and second-generation effects.
Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, UK.
A M
AM
Stewart
G W
GW
Kneale
D000367:Age Factors; D015331:Cohort Studies; D005260:Female; D005333:Fetus / Q000528:radiation effects; D006801:Humans; D008017:Life Expectancy; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000401:mortality*; D009689:Nuclear Warfare; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011832:Radiation Injuries / Q000401:mortality*; D015983:Selection Bias