Left ventricular assist with an axial flow pump (Hemopump): clinical application.
Eighteen patients suffering from acute left heart failure were selected as candidates for Hemopump support. In 6 patients, peripheral atheromatosis prevented insertion of the device. Of the remaining 12 patients, 9 had postcardiotomy shock, 2 had acute rejection after orthotopic heart transplantation, and 1 had acute myocardial infarction complicated by a large postinfarction ventricular septal defect. During Hemopump support, hemodynamics recovered in all patients. Major complications were related to mechanical pump failure, such as fracture of the drive cable and expulsion of the cannula out of the ventricle, or to hemolysis of variable degree. Seven patients (58%) survived and were discharged from the hospital: the 2 patients bridged to heart transplantation and 5 of the 9 postcardiotomy patients, including 1 who could not be weaned but later underwent successful transplantation. The patient with the postinfarction ventricular septal defect died after removal of the device because of hemolysis. These results indicate that the Hemopump is a relatively noninvasive and efficacious left ventricular system of moderate power.
Department of Cardiac Surgery, University Clinic Gasthuisberg, Katholieke Universiteit Leuven, Belgium.
A C
AC
Wiebalck
P F
PF
Wouters
F R
FR
Waldenberger
B
B
Akpinar
P M
PM
Lauwers
R H
RH
Demeyere
P T
PT
Sergeant
W J
WJ
Daenen
W J
WJ
Flameng
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D002302:Cardiac Output / Q000502:physiology; D002303:Cardiac Output, Low / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D002496:Central Venous Pressure / Q000502:physiology; D004867:Equipment Design; D004868:Equipment Failure; D005260:Female; D006084:Graft Rejection / Q000150:complications; D016027:Heart Transplantation / Q000009:adverse effects; D006353:Heart-Assist Devices / Q000009:adverse effects; D006461:Hemolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D012770:Shock, Cardiogenic / Q000150:complications; D015996:Survival Rate; D016896:Treatment Outcome; D016277:Ventricular Function, Left