Hypophosphataemic rickets after ifosfamide treatment in children.
Ifosfamide is a derivative of cyclophosphamide and is used to treat malignant tumours. One of its side effects is nephrotoxicity. Three children with previously normal renal function, who received ifosfamide for the treatment of Ewing's Sarcoma and subsequently developed hypophosphataemic rickets, are described.
Department of Radiology, Royal Belfast Hospital for Sick Children.
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LE
Sweeney
D002648:Child; D005198:Fanconi Syndrome / Q000139:chemically induced; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects*; D007719:Knee Joint / Q000000981:diagnostic imaging; D008297:Male; D010710:Phosphates / Q000097:blood*; D011859:Radiography; D012279:Rickets / Q000097:blood / Q000139:chemically induced* / Q000000981:diagnostic imaging; D012512:Sarcoma, Ewing / Q000188:drug therapy
D010710:Phosphates; D007069:Ifosfamide