Osmolarity and growth phase overlap in regulation of Salmonella typhi adherence to and invasion of human intestinal cells.
The study of the effects of osmolarity and growth phase on Salmonella typhi adherence to and invasion of Henle 407 epithelial cells provides the first evidence of a clear overlap between these two environmental stimuli. High-osmolarity conditions are required in the late-log phase for optimum induction of the adherent and invasive phenotypes.
Department of Microbiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799.
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D001422:Bacterial Adhesion; D002460:Cell Line; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D009994:Osmolar Concentration; D012485:Salmonella typhi / Q000254:growth & development / Q000472:pathogenicity*; D014774:Virulence