DNA profile of nephrogenic adenoma assessed by flow cytometry.
Nephrogenic adenoma is a metaplastic condition which usually involves the bladder urothelium within the clinical setting of chronic inflammation. Its presentation/endoscopic appearance may mimic bladder cancer and a premalignant potential has been speculated. DNA flow cytometry performed on involved bladder tissue revealed a diploid phenotype exhibiting low proliferative activity. These findings are most suggestive of a benign process.
Gaylis
F D
FD
Department of Urology, Northwestern University Medical School, Chicago, Illinois.
Keer
H N
HN
Bauer
K D
KD
Kozlowski
J M
JM
Grayhack
J T
JT
D000236:Adenoma / Q000235:genetics / Q000473:pathology*; D000328:Adult; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007684:Kidney Tubules / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000235:genetics / Q000473:pathology*
D004273:DNA, Neoplasm