Overexpression or polycyclic aromatic hydrocarbon-mediated induction of an apparently novel class 3 aldehyde dehydrogenase in human breast adenocarcinoma cells and its relationship to oxazaphosphorine-specific acquired resistance.
Department of Pharmacology, University of Minnesota, Minneapolis 55455.
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Sreerama
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Sladek
D000230:Adenocarcinoma / Q000201:enzymology*; D000444:Aldehyde Dehydrogenase / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D001943:Breast Neoplasms / Q000201:enzymology*; D004351:Drug Resistance; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D005982:Glutathione Transferase / Q000378:metabolism; D006801:Humans; D008748:Methylcholanthrene / Q000494:pharmacology; D009943:Organophosphorus Compounds / Q000378:metabolism / Q000494:pharmacology; D011083:Polycyclic Compounds / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000378:metabolism
D009943:Organophosphorus Compounds; D011083:Polycyclic Compounds; D008748:Methylcholanthrene; D000444:Aldehyde Dehydrogenase; D005982:Glutathione Transferase