Determination of ichthiomycin concentration by biological test with Cyprinus carpio L.
We have found out that one-year-old carps are extremely sensitive to ichthiomycin in concentrations between 25-125 micrograms/dm3. This fact permitted the use of biological methods for determination of ichthiomycin concentrations in cultural medium of Streptomyces levoris 1107 or crude preparations of the antibiotic.
Gameyska
Y
Y
Institute of Microbiology, Bulgarian Academy of Sciences.
Popov
K
K
Ognianov
I
I
Tishinova
R
R
Rachev
R
R
D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D000968:Antimycin A / Q000031:analogs & derivatives / Q000032:analysis; D001681:Biological Assay / Q000379:methods*; D002347:Carps; D004305:Dose-Response Relationship, Drug; D013302:Streptomyces; D013997:Time Factors
D000900:Anti-Bacterial Agents; C032456:antimycin; D000968:Antimycin A