Acute renal failure after exercise in a child with renal hypouricaemia.
We describe a 12-year-old boy with renal hypouricaemia who presented with acute renal failure after a 6-h sports training session. Back and loin pain were noted at presentation. Although serum creatinine and blood urea nitrogen were elevated, the serum uric acid concentration was normal (2.6 mg/dl). This decreased to 0.3 mg/dl after recovery. The pyrazinamide and probenecid tests revealed that the cause of renal hypouricaemia in this patient was totally defective uric acid reabsorption. Acute renal failure after exercise is a rare but serious complication in paediatric patients with renal hypouricaemia.
Department of Paediatrics, Faculty of Medicine, University of Tokyo, Japan.
T
T
Igarashi
T
T
Sekine
H
H
Sugimura
H
H
Hayakawa
T
T
Arayama
D058186:Acute Kidney Injury / Q000209:etiology*; D001806:Blood Urea Nitrogen; D002648:Child; D003404:Creatinine / Q000097:blood; D015444:Exercise; D006801:Humans; D008297:Male; D014527:Uric Acid / Q000097:blood*
D014527:Uric Acid; D003404:Creatinine