[The administration of corticoliberin into the caudate nucleus activates the sympathetic-adrenal medullary and hypophyseal-adrenal cortical systems by different mechanisms].
The activation was revealed, through a considerable increase of levels of adrenaline, noradrenaline and cortisol. Corticotropin-releasing factor seems to act upon the sympatho-adrenal system (SAS) via dopaminergic mediation. The mechanisms of triggering of the SAS and pituitary-adrenocortical system by the corticotropin-releasing factor seem to be different and due to involvement of different extrahypothalamic structures in the regulating contours.
Shaliapina
V G
VG
Rakitskaia
V V
VV
Garina
I A
IA
Voĭlokova
N L
NL
Suvorov
N F
NF
D000302:Adrenal Cortex / Q000187:drug effects* / Q000502:physiology; D000313:Adrenal Medulla / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D002421:Caudate Nucleus / Q000187:drug effects* / Q000502:physiology; D003346:Corticotropin-Releasing Hormone / Q000008:administration & dosage*; D003907:Dexamethasone / Q000494:pharmacology; D004285:Dogs; D004347:Drug Interactions; D016627:Oxidopamine / Q000494:pharmacology; D010902:Pituitary Gland / Q000187:drug effects* / Q000502:physiology; D013268:Stimulation, Chemical; D013564:Sympathetic Nervous System / Q000187:drug effects* / Q000502:physiology
D003907:Dexamethasone; D016627:Oxidopamine; D003346:Corticotropin-Releasing Hormone
Vvedenie kortikoliberina v khvostatoe iadro aktiviruet simpatoadrenomedulliarnuiu i gipofiz-adrenokortikal'nuiu sistemy raznymi mekhanizmami.