[Differentiating between tumor and implant material in the postoperative sella using MRT].
MRT criteria have been developed to distinguish between tumour and implant material following examination of 50 patients who had transsphenoidal hypophysectomies for tumours. Judgements were based on the postoperative hormonal status and the operation notes. Following contrast injection of Gd-DTPA and using T1 weighted spin-echo sequences, implant material appeared as sandwich-like, linear or circular structures. Residual recurrent tumour produced homogenous or non-homogenous aspects without marginal enhancement in 84% of cases. Postoperative displacement of the infundibulum to the opposite side was observed in 73% of patients with tumour remnants. Sensitivity of MRT was 70%, specificity 95%. There was a positive predictive value of 94% and a negative predictive value of 72% with an accuracy of 81%. This provides assistance in differentiating between tumour remnants and implant material. MRT is recommended as a method of examination for hypophyseal tumours to evaluate the success of surgery and where there is clinical doubt concerning residual or recurrent tumour.
Radiologische Universitätsklinik, Bonn.
W A
WA
Kaiser
V
V
Steckelbroeck
B
B
Siewert
G
G
Layer
A
A
Hochstetter
M
M
Reiser
D000236:Adenoma / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D005547:Foreign Bodies / Q000175:diagnosis* / Q000453:epidemiology; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007016:Hypophysectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D011184:Postoperative Period; D012189:Retrospective Studies
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
Differenzierung zwischen Tumor und Implantatmaterial in der postoperativen Sella mit der MRT.