Predictive value of neurological abnormalities in HIV 1 patients in the early stages of the infection.
A longitudinal clinical neurological and electrophysiological follow-up study was carried out on 31 HIV1 seropositive outpatients in the asymptomatic or LAS stages of the infection (CDC II-III). The results of clinical examination and multimodal evoked potentials (EP) recording showed a high percentage of abnormalities (42% and 39% of cases respectively); in a statistically significant number of subjects these abnormalities were predictive of subsequent immunological deterioration, thus demonstrating the close relationship between neurological and immunological functions in HIV1 infection.
Istituto di Clinica delle Malattie Nervose e Mentali, Università La Sapienza, Roma.
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Morocutti
D000328:Adult; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006679:HIV Seropositivity / Q000276:immunology / Q000503:physiopathology*; D015497:HIV-1; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D011237:Predictive Value of Tests; D013997:Time Factors