[The relation of moderate alcohol drinking and congestive heart insufficiency].
116 patients (53 women and 63 men) with congestive heart failure, secondary to chronic ischemic heart disease and/or hypertensive heart disease, were studied with the aim of assessing effects of moderate alcohol use on the clinical features of the disease. Two subgroups were considered: a) 57 moderate drinkers (11 women and 46 men); b) 59 non-drinkers or ex-drinkers (42 women, 17 men). Left ventricular mass/m2 (LVM/m2) is higher among moderate drinkers in comparison with non-drinkers (p < 0.001); this difference is present both in men (p < 0.05) and in women (p < 0.001). These results suggest that higher LVM/m2 of drinkers does not depend on sex and cigarette smoking; i.e., in males, a subgroup with the same prevalence of cigarette smokers among drinkers and non drinkers, congestive heart failure of drinkers is associated with a greater left ventricular enlargement. Our results suggest that moderate alcohol use can represent an additional pathogenetic factor for more severe clinical and laboratory features of congestive heart failure.
Clinica Medica, Università, Catania.
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Carpinteri
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Caruso
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Mazzone
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Trovato
D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects*; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects
Rapporti tra uso moderato di alcolici e insufficienza cardiaca congestizia.