Scanning microradiographic study of the kinetics of subsurface demineralization in tooth sections under constant-composition and small constant-volume conditions.
The kinetics of subsurface demineralization of tooth sections has been studied in real-time by scanning microradiography (SMR). Demineralization was carried out: (1) with a large volume of solution buffered to pH = 4 to maintain a constant composition; and (2) in a small constant volume (approximately 3 mL), buffered initially at pH = 4, so that the degree of saturation at the tooth surface increased as the tooth dissolved. At constant composition, the change in lesion depth, Y, with time, T, followed a linear relation, Y = a + bT, for T > 44 +/- 5 h. Before this time, the relation could be approximated by a linear one with different a and b constants. At constant volume, Y = q(1-e-r(T + s)) for all T, where q, r and s are constants. Similar relations, with different constants, were found for the mineral loss per unit area of lesion exposed to acid. These results showed that the process of demineralization under the rather severe conditions used was essentially a surface-controlled process. The change of slope at approximately 44 h and the presence of the constant s in the exponential function were attributed to a change in kinetics after formation of the surface layer.
Gao
X J
XJ
Department of Child Dental Health, London Hospital Medical College, United Kingdom.
Elliott
J C
JC
Anderson
P
P
D003743:Dental Enamel / Q000378:metabolism; D003804:Dentin / Q000378:metabolism; D004058:Diffusion; D006801:Humans; D008852:Microradiography; D008954:Models, Biological; D013499:Surface Properties; D013997:Time Factors; D017001:Tooth Demineralization / Q000378:metabolism* / Q000473:pathology