Scleroderma and autoimmune thrombocytopenia associated with ingestion of L-tryptophan.
We report the occurrence of scleroderma and autoimmune thrombocytopenia in a patient who took L-tryptophan as a muscle-building adjuvant. This is the first time such an association has been reported.
Morgan
J M
JM
Department of Dermatology, Carter Bequest Hospital, Middlesbrough, U.K.
Adams
S J
SJ
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000139:chemically induced* / Q000188:drug therapy; D001379:Azathioprine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012594:Scleroderma, Localized / Q000139:chemically induced* / Q000188:drug therapy; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000188:drug therapy; D014364:Tryptophan / Q000009:adverse effects*
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D014364:Tryptophan; D011239:Prednisolone; D001379:Azathioprine