Similarity of DNA fingerprints due to chance and relatedness.
Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance and relatedness. From these results, the degree of similarity due to relatedness alone may be calculated.
Department of Human Genetics, Graduate School of Public Health, University of Pittsburg, Pa. 15261.
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Li
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Weeks
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Chakravarti
D000483:Alleles; D016172:DNA Fingerprinting; D005190:Family; D006801:Humans; D011336:Probability