Site-directed mutagenesis of mammalian alcohol and sorbitol dehydrogenases map functional differences within the enzyme family.
Höög
J O
JO
Department of Chemistry I, Karolinska Institutet, Stockholm, Sweden.
Karlsson
C
C
Eklund
H
H
Shapiro
R
R
Jörnvall
H
H
D000426:Alcohol Dehydrogenase / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D006801:Humans; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D007700:Kinetics; D007064:L-Iditol 2-Dehydrogenase / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D051381:Rats; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D013379:Substrate Specificity
D007527:Isoenzymes; D011994:Recombinant Proteins; D000426:Alcohol Dehydrogenase; D007064:L-Iditol 2-Dehydrogenase