Development of an all-in-one percutaneous cardiopulmonary support system.
This paper deals with development of an all-in-one percutaneous cardiopulmonary support (PCPS) system. In recent years, PCPS has been used for the treatment of acute myocardial infarction. A prototype of a compact all-in-one PCPS system was developed. The system contains a centrifugal pump and an extra-capillary flow-type membrane lung in one body. The system has a priming volume of 250 ml, which allows for PCPS with no additional blood. The in vitro tests and an ex vivo test were conducted. The system produces 1.6-5 L/min of flow in the experiments. The O2 transfer rate was 310 ml/min, and the CO2 transfer rate was 300 ml/min at a blood flow rate of 5 L/min. This device is compact, requires less priming volume than a standard system, and is easy-to-handle in the experiments. The system is considered applicable to percutaneous cardiopulmonary support.
Fukui
Y
Y
Department of Applied Electronic Engineering, Faculty of Science and Engineering, Tokyo Denki University, Japan.
Kawamura
T
T
Higami
T
T
Funakubo
A
A
Sakuma
I
I
D000818:Animals; D001783:Blood Flow Velocity; D002417:Cattle; D004867:Equipment Design; D006353:Heart-Assist Devices / Q000009:adverse effects; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D066298:In Vitro Techniques; D008961:Models, Structural; D011659:Pulmonary Gas Exchange
D006454:Hemoglobins