Igh-6b expression in BALB.nude mice.
Mice that differ at Igh loci and the reagents that permit resolution of such distinctions are powerful genetic tools for studying B cell heterogeneity. In this report, IgM-allotype-specific ELISA revealed that two of three sources of mice designated as BALB.nude express the Igh-6b (IgMb) allotype characteristic of C57BL mice. This observation serves to warn investigators that not all strains of mice designated BALB.nude express the Igh-6a (IgMa) allotype.
Division of Immunology, Medical Biology Institute, La Jolla, California 92037.
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Riggs
D000818:Animals; D005803:Genes, Immunoglobulin; D007126:Immunoglobulin Allotypes / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C / Q000276:immunology*; D008819:Mice, Nude / Q000276:immunology*
D007126:Immunoglobulin Allotypes