Are we at risk for heart disease because of normal iron status?
A recent prospective three-year follow-up study of 1931 men in Finland demonstrated a significant 2.2-fold greater risk of acute myocardial infarct in 42- to 60-year-old men who had serum ferritin concentrations above 200 micrograms/dL. However, the mean plasma ferritin concentration in this population was high and the prevalence of hemochromatosis was unknown; these issues mitigate the suggestion that high-normal iron stores leads to heart disease.
Beard
J L
JL
Pennsylvania State University, University Park 16802.
D000328:Adult; D005293:Ferritins / Q000097:blood; D005387:Finland; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D012307:Risk Factors
D005293:Ferritins; D007501:Iron