Adjuvant activity of the Escherichia coli WF table L-form cytoplasmic membranes.
It was established that the stable E. coli WF+ L-form cytoplasmic membranes (CM) increase the antibody response in rabbit during experimental hyperimmunization with cells of Streptococcus pyogenes A49 and Proteus mirabilis D52. Using the skin-induration test and the reaction for aggregation of macrophages in presence of homologous antigens it was established that CM increase the cell-mediated immunity of guinea-pigs to protein antigens of the same bacterial strains.
Ivanova
E
E
Institute of Microbiology, Bulgarian Academy of Sciences.
Kenarova
B
B
Gumpert
J
J
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D002449:Cell Aggregation / Q000187:drug effects / Q000276:immunology; D002462:Cell Membrane / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology*; D005260:Female; D006168:Guinea Pigs; D007111:Immunity, Cellular / Q000187:drug effects; D007114:Immunization / Q000379:methods; D007740:L Forms / Q000276:immunology*; D008264:Macrophages / Q000187:drug effects / Q000276:immunology; D008297:Male; D011513:Proteus mirabilis / Q000276:immunology; D011817:Rabbits; D012882:Skin Tests; D013297:Streptococcus pyogenes / Q000276:immunology
D000276:Adjuvants, Immunologic