Relative risk of development and active detection of primary multiple endometrial, breast and ovarian cancer.
The cumulative relative risk of polyneoplasia and the factors which influence it were retrospectively studied in 8065 primary patients (1400 endometrial cancer, 5450 breast cancer, 1215 ovarian cancer). In breast cancer the cumulative risk of patients developing synchronous corpus uteri cancer is 13.9 times higher than in the general population. In corpus uteri cancer patients risk of breast cancer 9.0. The indices mentioned increase from the age of 40-59 years and in the first stage. In prospective research mammography and ultrasonic examination of the pelvis were carried out in 481 patients of primary corpus uteri cancer. Asymptomatic initial patients of primary corpus uteri cancer. Asymptomatic initial breast cancer of the first stage was detected in 1.9%, 19 times more frequently than in the controls (24.29 practically healthy women). Among 318 primary breast cancer patients cytologic examination of endometrial material allowed us to detect endometrial cancer in 2.4% (6 times more frequent than in the controls), and under echography ovarian cancer of the 1.st-2.rd stages was diagnosed in 1.3%.
Prof. Petrov Scientific Research Institute of Oncology, Ministry of Health, Leningrad.
J B
JB
Bokhman
S J
SJ
Maximov
D000328:Adult; D000368:Aged; D001706:Biopsy; D001943:Breast Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D008327:Mammography; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000453:epidemiology* / Q000209:etiology; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D010388:Pelvis / Q000000981:diagnostic imaging; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D014463:Ultrasonography; D014626:Vaginal Smears