Capsular types and susceptibility to penicillin of pneumococci isolated from cerebrospinal fluid or blood in Denmark, 1983-1988.
By means of the capsular reaction test, we typed 2,294 pneumococcal strains isolated from blood or cerebrospinal fluid (CSF) in Denmark during 1983-88.91% of the strains belonged to types included in the 23-valent vaccine. Among 254 pneumococcal isolates from blood and CSF from Danish children, types 6A + 6B, 18C, 14, 7F, 1 and 19F, in that order of frequency, were the most common ones, accounting for 68%. Among 2,031 pneumococcal strains from adults, the most common isolates were types 1, 3, 14, 7F, 4, and 6A + 6B, accounting for 50% of all pneumococcal strains isolated from patients with invasive disease. Penicillin-resistant invasive strains of Streptococcus pneumoniae are rare in Denmark (< 1%).
Collaborating Centre for Reference and Research on Pneumococci, Statens Seruminstitut, Copenhagen, Denmark.
S V
SV
Nielsen
J
J
Henrichsen
D000293:Adolescent; D016667:Bacterial Capsules / Q000187:drug effects*; D015373:Bacterial Typing Techniques; D001769:Blood / Q000382:microbiology*; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D003718:Denmark; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology*; D013296:Streptococcus pneumoniae / Q000145:classification / Q000302:isolation & purification*; D013997:Time Factors
D010406:Penicillins