The use of glucagon in a case of calcium channel blocker overdose.
The hypotension and myocardial depression that result from calcium channel blocker ingestion often are refractory to standard therapeutic modalities. Anecdotal reports on the use of glucagon have failed to show significant hemodynamic improvement. We report the first case of calcium channel blocker overdose that responded to glucagon. We conclude that glucagon is safe and effective in the management of hemodynamic instability associated with calcium channel blocker poisonings.
Department of Emergency Medicine, Mercy Catholic Medical Center, Philadelphia.
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S
Doyon
J R
JR
Roberts
D000208:Acute Disease; D000368:Aged; D001919:Bradycardia / Q000188:drug therapy / Q000209:etiology; D004280:Dobutamine / Q000627:therapeutic use; D004298:Dopamine / Q000627:therapeutic use; D062787:Drug Overdose / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D005934:Glucagon / Q000627:therapeutic use*; D006801:Humans; D007022:Hypotension / Q000188:drug therapy / Q000209:etiology; D012770:Shock, Cardiogenic / Q000188:drug therapy / Q000209:etiology; D014700:Verapamil / Q000506:poisoning*
D004280:Dobutamine; D005934:Glucagon; D014700:Verapamil; D004298:Dopamine