Activation of the various cyclin/cdc2 protein kinases.
Recent research has led to the near culmination of the biochemical confirmation of the most basic genetic predictions about how p34cdc2 activity is controlled. The field is now moving from a biochemical dissection of the machinery to understanding how the system is regulated. The discovery of numerous, highly related protein kinase complexes that control other cell cycle events will test the generality of this paradigm.
Solomon
M J
MJ
Yale University, New Haven.
D000818:Animals; D001665:Binding Sites; D016203:CDC2 Protein Kinase; D002453:Cell Cycle; D006801:Humans; D010766:Phosphorylation; D012440:Saccharomyces
D016203:CDC2 Protein Kinase