[Photoimmunology of melanoma].
Several epidemiological studies suggest that exposure to ultraviolet radiation and immunological responsiveness of the host contribute to the etiology of melanoma. In addition, a growing experimental evidence indicates a stimulant effect of ultraviolet radiation and a high immunogenicity of melanocytic tumors. These findings lead to the hypothesis of an ultraviolet-induced alteration of the immune response that decreases the host-resistance to melanoma antigens.
Service de Dermatologie I, CHU, Besançon.
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F
Aubin
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P
Agache
D000818:Animals; D006801:Humans; D007108:Immune Tolerance; D008545:Melanoma / Q000209:etiology* / Q000276:immunology; D051379:Mice; D012878:Skin Neoplasms / Q000209:etiology* / Q000276:immunology; D014466:Ultraviolet Rays / Q000009:adverse effects*
La photoimmunologie du mélanome.