Unilateral linear lichenoid eruption after bone marrow transplantation: an unmasking of tolerance to an abnormal keratinocyte clone?
Chronic cutaneous graft-versus-host disease may appear clinically as a lichenoid eruption. We describe a 26-year-old man who developed a unilateral linear lichenoid eruption 7 months after allogeneic bone marrow transplantation. We believe this represents an unusual form of localized, chronic graft-versus-host disease. The possible relationship to viral infection or cellular mosaicism and the clinical, histologic, and immunologic similarities to idiopathic lichen planus are discussed.
Beers
B
B
Division of Dermatology, University of Florida College of Medicine.
Kalish
R S
RS
Kaye
V N
VN
Dahl
M V
MV
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002999:Clone Cells; D006086:Graft vs Host Disease / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007108:Immune Tolerance; D015603:Keratinocytes / Q000276:immunology / Q000473:pathology; D007642:Keratosis / Q000473:pathology; D017512:Lichenoid Eruptions / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D008297:Male