[Preoperative monitoring of blood coagulation in urologic operations: diagnosis of familial factor XI deficiency within the scope of preoperative blood coagulation studies].
Presurgical coagulation diagnosis should--apart from coagulation monitoring in the laboratory based on a stepwise diagnosis for detection of coagulations disorders, starting with global tests (NT/APTT) followed by appropriate specific investigation in case of pathological findings--consist of an adequate hemostaseological anamnesis and physical checkup of the patient. This would allow detection of important signs of hemostaseological impairment during the pre-analytical phase already and permit subsequent initiation of more specific coagulation tests. The casuistics of a patient with factor XI-deficiency ("Minor Form"), a condition which is extremely infrequent in our country, demonstrates the coagulation diagnostic procedure which led to detection of his inherited factor XI-deficiency. In addition the pre-, peri- and postsurgical therapeutical management of this particular patient using an antifibrinolytic drug (tranexamic acid) is presented.
Zentrallaboratorium, Krankenhauses der Stadt Wien-Lainz.
A
A
Haushofer
W M
WM
Halbmayer
E
E
Toth
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H
Pflüger
D001780:Blood Coagulation Tests; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D003955:Diagnostic Tests, Routine; D005173:Factor XI Deficiency / Q000097:blood / Q000175:diagnosis / Q000235:genetics*; D006474:Hemorrhagic Disorders / Q000097:blood / Q000235:genetics / Q000517:prevention & control; D006801:Humans; D008297:Male; D010375:Pedigree; D010688:Phimosis / Q000097:blood / Q000235:genetics / Q000601:surgery*; D011183:Postoperative Complications / Q000097:blood / Q000517:prevention & control
Präoperatives Gerinnungsmonitoring bei urologischen Operationen: Diagnostik eines familiären Faktor-XI-Mangels im Rahmen einer präoperativen Gerinnungsuntersuchung.