Kasabach-Merritt syndrome with profound platelet support.
The Kasabach-Merritt Syndrome describes thrombocytopenia occurring in patients with giant hemangiomata. The resultant thrombocytopenia may be profound and occasionally even life-threatening. An 11-month-old infant with prolonged thrombocytopenia whose course was complicated by recurrent hemorrhaging requiring intense platelet transfusions is reported. During her 19-month hospitalization she received 6,622 platelet concentrates. This represents the most extensive platelet support ever given to an infant with this syndrome.
Department of Pathology, Indiana University Medical Center, School of Medicine, Indianapolis 46202-5283.
J D
JD
Henley
C F
CF
Danielson
S S
SS
Rothenberger
Y
Y
Hsueh
A
A
Thelia
L J
LJ
McCarthy
D016913:Blood Component Transfusion; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000150:complications / Q000473:pathology; D005260:Female; D006391:Hemangioma / Q000097:blood* / Q000473:pathology; D006801:Humans; D007223:Infant; D017713:Platelet Transfusion; D013577:Syndrome; D013921:Thrombocytopenia / Q000097:blood* / Q000473:pathology