[Autopsy case of non-invasive thymoma associated with pancytopenia and hypogammaglobulinemia].
A 57-year-old male presented with palpitations and dyspnea on exertion. Examination of the peripheral blood and bone marrow showed pancytopenia with marked red cell aplasia. Hypogammaglobulinemia was also recognized. Chest X-ray and CT showed a mass in the anterior mediastinum. A biopsy showed thymoma. Two months after admission, the patient died of sepsis secondary to worsening pancytopenia and hypogammaglobulinemia. Autopsy showed non-invasive spindle cell type thymoma and a marked decrease of hematogenous cells. Review of the literature indicates that pancytopenia associated with thymoma is resistant to all forms of treatment and its prognosis is poor.
Department of Surgery, Saiseikai Central Hospital.
H
H
Nomori
R
R
Kobayashi
Y
Y
Takahashi
R
R
Iga
S
S
Morinaga
D000361:Agammaglobulinemia / Q000150:complications*; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000150:complications*; D011379:Prognosis; D018805:Sepsis / Q000150:complications; D013945:Thymoma / Q000150:complications / Q000473:pathology*; D013953:Thymus Neoplasms / Q000150:complications / Q000473:pathology*