Life-threatening haemorrhage in a patient with rheumatoid arthritis and a lupus anticoagulant coexisting with acquired autoantibodies against factor VIII.
A case history of a patient with RA and a lupus anticoagulant coexisting with an acquired inhibitor to factor VIII is described. The factor VIII inhibitor was heralded by life-threatening haemorrhage which followed an invasive procedure.
Ballard
H S
HS
Department of Veterans' Affairs, Medical Centre, New York, NY 10010.
Nyamuswa
G
G
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood*; D001706:Biopsy / Q000009:adverse effects*; D005169:Factor VIII / Q000037:antagonists & inhibitors / Q000276:immunology*; D006470:Hemorrhage / Q000209:etiology* / Q000628:therapy; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D008297:Male
D001323:Autoantibodies; D016682:Lupus Coagulation Inhibitor; D005169:Factor VIII