Results of treatment with pollen extract (Cernilton N) in chronic prostatitis and prostatodynia.
We report the results of a prospective study with the pollen extract, Cernilton N, in a dose of 1 tablet tid for 6 months for the treatment of chronic prostatitis syndrome in 90 patients. The factors documented before and after 3 and 6 months' treatment were digital rectal examination (DRE) of the prostate, uroflowmetry, bacterial studies, leucocyte counts in urine and measurement of complement C3/coeruloplasmin in the seminal fluid. The patients were divided into 2 groups: those without associated complicating factors (CFs) (n = 72) and those with complicating factors, i.e. urethral strictures, prostatic calculi, bladder neck sclerosis (n = 18). In the group without CFs, 56 (78%) had a favorable response; 26 (36%) were cured of their symptoms and signs and 30 (42%) improved significantly with an increase in flow rate, a reduction in leukocyturia in the post-prostate massage urine (VB3) and a decrease in complement C3/coeruloplasmin in the ejaculate. In the patients with CFs only 1 patient showed a response. Complicating factors should be considered in patients who fail to respond to treatment within 3 months. Cernilton N was well tolerated by 97% of patients.
Department of Urology, Georg-August-University, Göttingen, Germany.
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Rugendorff
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Weidner
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Ebeling
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Buck
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002570:Ceruloplasmin / Q000032:analysis; D002908:Chronic Disease; D003176:Complement C3 / Q000737:chemistry; D006801:Humans; D007958:Leukocyte Count; D007970:Leukopenia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D010936:Plant Extracts / Q000627:therapeutic use*; D011446:Prospective Studies; D011472:Prostatitis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D012212:Rheology; D012434:Secale; D016896:Treatment Outcome; D014554:Urination; D014563:Urodynamics
D003176:Complement C3; D010936:Plant Extracts; C010070:cernilton; D002570:Ceruloplasmin