[Neuroradiologic methods and findings prior to the surgical treatment of epilepsy in children].
Epilepsy in childhood is often caused by morphological abnormalities and is frequently pharmacoresistant. Therefore it represents a challenge to the neuroradiologist because early and accurate diagnosis of abnormal morphology is the basis for planning surgical intervention with a high chance of controlling seizures and a low risk of complications. Both morphological (radiography, CT, MRI and angiography) and functional examinations [intracarotid amobarbital test (IAT)] are essential parts of the presurgical evaluation. In most cases MRI has proved to be most sensitive in detecting lesions except for some calcifications. Routine protocols for brain examinations are not sufficient, missing about 22% of lesions. Therefore a refined MRI and CT protocol is proposed. Even in very young children IAT can be performed at very low risk; these tests contribute highly valuable information about actual hemispheric dominance and other functions in more than 80% of procedures that is indispensable if postoperative neurological and neuropsychological deficits are to be avoided.
Epileptologische Klinik, Universität Bonn.
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B
Ostertun
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L
Solymosi
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M
Kurthen
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CE
Elger
J
J
Schramm
D000293:Adolescent; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D004292:Dominance, Cerebral / Q000502:physiology; D004827:Epilepsy / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed
Neuroradiologische Methoden und Befunde vor epilepsiechirurgischen Eingriffen im Kindesalter.