The use of antibiotic/steroid ear drops to reduce post-operative otorrhoea and blockage of ventilation tubes. A prospective study.
This prospective randomized study investigates whether the use of antibiotic/steroid ear drops (Betnesol-N) is effective in reducing early post-operative otorrhoea and blockage of ventilation tubes (VTs). The study included 162 children who had bilateral VT insertion and used Betnesol-N ear drops in one ear only for three days after surgery, the other ear was left as control. These children were reviewed two weeks later and their ears were examined for VT patency, presence of blood or of mucopus. Statistical analysis of our results showed that the use of Betnesol-N ear drops has significantly reduced the incidence of post-operative otorrhoea within two weeks of VTs insertion (p < 0.01). However, these drops did not have a significant effect on the blockage rates of VTs with dried blood (p > 0.05).
Department of Otolaryngology and Head and Neck Surgery, South Warwickshire Hospital, Warwick.
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MA
Salam
H R
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Cable
D001623:Betamethasone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008876:Middle Ear Ventilation; D009355:Neomycin / Q000627:therapeutic use*; D010034:Otitis Media with Effusion / Q000601:surgery*; D010035:Otitis Media, Suppurative / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies
D004338:Drug Combinations; C081596:betamethasone, neomycin drug combination; D001623:Betamethasone; D009355:Neomycin