[Cutaneous candidiasis due to Candida parapsilosis occurring in the course of idiopathic aplastic anemia].
Candida parapsilosis is a very common and saprophytic fungus. Its pathogenic role has been reported in intensive care units after invasive instrumentations. We report a case of dermal candidiasis due to Candida parapsilosis occurring in an immunocompromised patient suffering from aplastic anemia treated with corticosteroids. The histopathological aspect was non specific, showing a polymorphous granulomatous reaction in the middermis. Findings of periodic acid-Schiff and Grocott-Gomori stains revealed a large number of pseudohyphae and spores. Candida parasilosis was cultured from a skin biopsy. The route of skin infection is discussed: direct inoculation or septic localization after fungemia.
Service d'Anatomie Pathologique, CHU Trousseau, Tours.
M C
MC
Machet
E
E
Diot
E
E
Stéphanov
N
N
Cochelin
D
D
Richard-Lenoble
A
A
De Muret
L
L
Machet
M C
MC
Grangeponte
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000368:Aged; D000369:Aged, 80 and over; D000741:Anemia, Aplastic / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D002179:Candidiasis, Cutaneous / Q000150:complications* / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male
D000305:Adrenal Cortex Hormones
Candidose cutanée à Candida parapsilosis survenant au cours d'une aplasie médullaire idiopathique.