S-100 protein in normal and pathologic oral tissues. A review.
S-100 protein is an acidic calcium binding protein widely distributed in different tissues and cells of different origin. The precise biological role of S-100 is still unknown, but several features suggest a function activity for this protein. Oral tissues have not been extensively studied for S-100 protein presence. Here, we review the investigations of S-100 protein content in normal oral tissues and oral pathological lesions. The immunolocalization of this protein is used to demonstrate evidence of neuroectodermal histogenesis and is useful in the differential diagnosis of certain neoplasms or proliferative conditions.
Lombardi
T
T
Division of Stomatology and Oral Surgery, School of Dental Medicine, Geneva.
Samson
J
J
D005881:Gingiva / Q000378:metabolism; D006801:Humans; D009055:Mouth / Q000378:metabolism*; D009059:Mouth Diseases / Q000378:metabolism*; D009061:Mouth Mucosa / Q000378:metabolism; D009062:Mouth Neoplasms / Q000378:metabolism; D009808:Odontogenic Tumors / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism*; D012469:Salivary Glands / Q000378:metabolism; D014070:Tooth / Q000378:metabolism
D009418:S100 Proteins