[Prognostic factors and their importance in the modification of therapeutic approaches in patients with Hodgkin's disease].
A prognostic study was performed in a group of 236 long-term followed patients. Eleven factors in total were included into a multivariate analysis--they were global, clinical and therapeutical factors. For complete remission, clinical stage, age at the time of diagnosis and size of affliction of mediastinum are important. Signs of poor prognosis for complete remission are "bulky" mediastinal disease, male sex and absence or reduction of chemotherapy in primary treatment. Prognostic factors as to the total survival are age at the time of diagnosis, clinical stage, total number and size of afflicted lymphatic areas and absence or reduction of chemotherapy in primary treatment. Emphasis is laid upon evaluation of the amount of individual risk to adjust therapeutic procedures to every individual patient.
Interní klinika 1. LF UK, Praha.
E
E
Vernerová
P
P
Tesarová
Z
Z
Hermanská
Z
Z
Dienstbier
P
P
Chytrý
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis
Prognostické faktory a jejich význam pro modifikaci lécebného postupu u nemocných s Hodgkinovou chorobou.