Endocrine-like cells and insulin-binding sites in the epineurium of Helix pomatia.
Endocrine/paracrine-like cells are described for the first time in the epineurium of the cerebro-subesophageal ganglia connectives and in the epineurium of the nervus pallialis dexter et internus of Helix pomatia. At least a population of these cells contains insulin-immunoreactive material. Immunoelectron-microscopic investigations showed that electron-dense granules exhibit insulin-like material. Insulin-binding studies revealed granular cells as putative target-cells of insulin in the epineurium.
University of Salzburg, Department of Physiology, Austria.
H H
HH
Kerschbaum
K
K
Holzinger
A
A
Hermann
D000818:Animals; D003238:Connective Tissue / Q000378:metabolism*; D003239:Connective Tissue Cells; D004702:Endocrine Glands / Q000166:cytology; D006372:Helix, Snails / Q000378:metabolism*; D010525:Peripheral Nerves / Q000502:physiology*; D011972:Receptor, Insulin / Q000032:analysis*
D011972:Receptor, Insulin