Signal transduction in Bacillus subtilis sporulation.
The initiation of sporulation in Bacillus subtilis is regulated by a signal transduction system leading to activation (by phosphorylation) of the Spo0A transcription factor. Activated Spo0A controls the expression of genes encoding different RNA polymerase sigma factors, whose synthesis and activities are related to morphological events and intercompartmental communication between the developing forespore and the mother cell.
Department of Molecular and Experimental Medicine, Scripps Research Institute La Jolla, CA 92037.
M A
MA
Strauch
J A
JA
Hoch
D001412:Bacillus subtilis / Q000235:genetics / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D008561:Membrane Fusion; D008954:Models, Biological; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D011505:Protein-Tyrosine Kinases / Q000235:genetics / Q000502:physiology; D012808:Sigma Factor / Q000235:genetics / Q000502:physiology; D015398:Signal Transduction; D013171:Spores, Bacterial; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology
D001426:Bacterial Proteins; D012808:Sigma Factor; D014157:Transcription Factors; D011505:Protein-Tyrosine Kinases