Ocular and neurological Behçet's disease without orogenital ulceration?
A 28 year old West Indian patient is described who had a relapsing and remitting steroid-sensitive illness for 3 years. The clinical features included uveitis and widespread CNS involvement. The patient was treated as though he had neurosarcoidosis. Post mortem examination revealed histological changes compatible with a diagnosis of Behçet's disease, but at no time did he suffer from oral or genital ulceration or arthritis. The authors suggest a new term to encompass such an entity: the "Behçet's MINUS" syndrome (multifocal intermittent neurological and uveitic syndrome).
Department of Neurology, National Hospital for Neurology and Neurosurgery, London, UK.
C J
CJ
Lueck
M
M
Pires
A C
AC
McCartney
E M
EM
Graham
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis*; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000648:ultrastructure; D001927:Brain Diseases / Q000175:diagnosis / Q000503:physiopathology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004401:Dysarthria / Q000150:complications; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011859:Radiography; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy; D014605:Uveitis / Q000150:complications; D014786:Vision Disorders / Q000150:complications
D000995:Antitubercular Agents; D011239:Prednisolone