[The mechanisms of the formation of the plateau phase of the ureteral action potential].
The duration of the AP plateau was shown to be controlled by the Na+ and Li+ ions in the solution incubating the smooth muscle of the ureter. Addition of ouabain to the sodium solution or replacement of the Na+ ions by the Li+ those shorted the plateau duration. The generation of the AP plateau seems to be due to participation of the Na(+)-Ca++ exchange mechanism.
Kazarian
K V
KV
Oganesian
A S
AS
Akopian
R R
RR
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002118:Calcium / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008094:Lithium / Q000494:pharmacology; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D010042:Ouabain / Q000494:pharmacology; D010477:Perfusion / Q000379:methods; D012964:Sodium / Q000494:pharmacology; D014513:Ureter / Q000502:physiology*
D010042:Ouabain; D008094:Lithium; D012964:Sodium; D002118:Calcium
O nekotorykh mekhanizmakh formirovaniia fazy plato potentsiala deĭstviia mochetochnika.