Bending membranes to the task: structural intermediates in bilayer fusion.
Merger of lipid bilayers plays a central role in diverse biological fusion reactions. Recent studies suggest that different membrane fusion systems, including fusion of purely lipid bilayers, involve formation of similar stalk-type intermediates--highly bent (net negative curvature) and transient lipidic connections between fusing membranes.
Laboratory of Theoretical and Physical Biology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1855, USA.
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LV
Chernomordik
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J
Zimmerberg
D002462:Cell Membrane / Q000737:chemistry / Q000502:physiology; D008051:Lipid Bilayers / Q000737:chemistry*; D008561:Membrane Fusion
D008051:Lipid Bilayers