sIL-2R levels in rheumatoid arthritis: poor correlation with clinical activity is due in part to disease duration.
The serum levels of soluble interleukin-2 receptors (sIL-2R) were measured in an attempt to determine whether they correlated with 'disease activity' in 59 patients suffering from rheumatoid arthritis. Our results indicate that serum levels of sIL-2R do not permit patients to be classified as having active or inactive disease according to standard clinical indices. A correlation between sIL-2R and disease duration could offer one explanation for the current discrepancies found in the literature.
Service de Rhumatologie, Centre Hospitalier Lyon Sud, France.
J G
JG
Tebib
M C
MC
Letroublon
E
E
Noel
J
J
Bienvenu
M
M
Bouvier
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D006801:Humans; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D012044:Regression Analysis; D012720:Severity of Illness Index; D012995:Solubility; D013997:Time Factors
D015415:Biomarkers; D015375:Receptors, Interleukin-2