[A case of rabies encephalitis with long survival. Clinical pathological correlations].
We present a case of a 22 year old male patient who developed a rabies encephalomyelitis with evolution of six weeks, treated first as a psychiatric disorder and later as an encephalitis. This case had the following important features; 1--A long time with the disease: usually the patients die into the first eight days after diagnosis; 2--The evident reactive gliosis; 3--Almost all the studied fields showed inclusion bodies in both supratentorial and infratentorial portions; 4--The hippocampus and spinal cord neurons had many or unique Negri bodies and some of those were giant; 5--Microglia proliferation and free acidophilus bodies. All those microscopic features mean a long evolution time that is rarely seen in this illness; in medical literature we found only ten long duration cases.
Servicio de Neurocirugía del Hospital de Especialidades del Centro Médico Nacional Siglo XXI.
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Guinto
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Felix
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Rivas
D000328:Adult; D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D018792:Encephalitis, Viral / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology*; D006801:Humans; D007181:Inclusion Bodies, Viral; D008297:Male; D011818:Rabies / Q000175:diagnosis / Q000401:mortality* / Q000473:pathology*; D013997:Time Factors
Un caso de encefalitis rábica de larga evolución. Correlación clínico patológica.