[Cutaneous manifestations of primary Sjögren's syndrome].
Cutaneous manifestations including purpura, annular erythema and pernio-like erythema are one of the extraglandular findings of primary Sjögren's syndrome (SS). Histopathologically, inflammatory vascular lesions are frequently detected. Two types of annular erythema, edematous and atrophic types, can be seen. Histopathologically, atrophic annular erythema is hardly distinguished from SCLE. Skin lesions of primary SS, especially purpura and edematous annular erythema, are related with anti-SS-A/Ro and SS-B/La antibodies. Some of the cutaneous manifestations develop both in primary SS and lupus erythematosus and anti-SS-A/Ro and SS-B/La antibodies may play an important role in the development of these cutaneous lesions.
Center for Adult Diseases Kurashiki, Minami Kurashiki Hospital.
S
S
Nishiyama
S
S
Miyawaki
T
T
Hashimoto
D000974:Antibodies, Antinuclear / Q000032:analysis; D006801:Humans; D012859:Sjogren's Syndrome / Q000150:complications* / Q000276:immunology; D012871:Skin Diseases / Q000209:etiology*
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies; C035357:SS-B antibodies