T-lymphocyte proliferation stimulated by alpha beta TCR/CD2 bispecific antibody is dependent on LFA-1/ICAM-1 recognition of accessory cells.
University of Manchester, U.K.
M E
ME
Di Mauro
A
A
Ager
D000818:Animals; D018033:Antibodies, Bispecific / Q000494:pharmacology*; D000938:Antigen-Presenting Cells / Q000276:immunology*; D018821:CD18 Antigens / Q000378:metabolism; D018801:CD2 Antigens / Q000378:metabolism; D066298:In Vitro Techniques; D039041:Integrin alpha4beta1; D016023:Integrins / Q000378:metabolism; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism; D008213:Lymphocyte Activation; D016169:Lymphocyte Function-Associated Antigen-1 / Q000378:metabolism; D051379:Mice; D051381:Rats; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000378:metabolism; D016201:Receptors, Lymphocyte Homing / Q000378:metabolism; D013601:T-Lymphocytes / Q000276:immunology*
D018033:Antibodies, Bispecific; D018821:CD18 Antigens; D018801:CD2 Antigens; D039041:Integrin alpha4beta1; D016023:Integrins; D016169:Lymphocyte Function-Associated Antigen-1; D016693:Receptors, Antigen, T-Cell, alpha-beta; D016201:Receptors, Lymphocyte Homing; D018799:Intercellular Adhesion Molecule-1