Swyer-James syndrome associated with Noonan syndrome: report of a case.
A 28-year-old man with Noonan syndrome associated with unilateral hyperlucent lung is reported. He had the typical craniofacial appearance and short stature of Noonan syndrome; he had mild mental retardation, atrophic testis, mild funnel chest and kyphosis. cardiovascular abnormalities included asymmetric hypertrophic cardiomyopathy and a significantly different caliber of the left and right pulmonary arteries. The unilateral hyperlucent lung was shown to result from acquired nondestructive emphysema caused by nonvalvular obstruction of the bronchi (Swyer-James syndrome or Macleod's syndrome). To the authors' knowledge, this is the first reported case of Noonan syndrome associated with Swyer-James syndrome.
Lin
Y M
YM
Department of Internal Medicine, Taiwan Provincial Feng Yuan Hospital, Taichung, Feng Yuan, ROC.
Huang
W L
WL
Hwang
J J
JJ
Ko
Y L
YL
Lien
W P
WP
D000328:Adult; D000402:Airway Obstruction / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D009634:Noonan Syndrome / Q000150:complications*; D011656:Pulmonary Emphysema / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography; D013577:Syndrome