Characterization of Actinobacillus pleuropneumoniae riboflavin biosynthesis genes.
In this paper, we report the identification, cloning, and complete nucleotide sequence of four genes from Actinobacillus pleuropneumoniae that are involved in riboflavin biosynthesis. The cloned genes can specify production of large amounts of riboflavin in Escherichia coli, can complement several defined genetic mutations in riboflavin biosynthesis in E. coli, and are homologous to riboflavin biosynthetic genes from E. coli, Haemophilus influenzae, and Bacillus subtilis. The genes have been designated A. pleuropneumoniae ribGBAH because of their similarity in both sequence and arrangement to the B. subtilis ribGBAH operon.
Fuller
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TE
Department of Microbiology, Michigan State University, East Lansing 48824, USA.
Mulks
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MH
D016977:Actinobacillus pleuropneumoniae / Q000235:genetics* / Q000378:metabolism; D000595:Amino Acid Sequence; D001483:Base Sequence; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D012256:Riboflavin / Q000096:biosynthesis* / Q000235:genetics
D012256:Riboflavin