Potentially active antimicrobial agents from 2-benzenesulfonyloxyphenyl-3,1-benzoxazine-4-one derivative.
Fourteen of nitrogeneous heterocyclic compounds that accommodate the sulfonate-ester moiety were synthesized through interaction of 2-benzenesulfonylo xyphenyl-3,1-benzoxazine-4-one with some nucleophilic reagents. The assigned structures for the prepared new compounds were confirmed on the basis of elemental and spectral data. Evaluation of the antimicrobial activity of these products, relative to standard antibiotics was tested and discussed.
Habib
O M
OM
Chemistry Department, Mansoura Faculty of Science, Egypt.
Moawad
E B
EB
Girges
M M
MM
el-Shafei
A M
AM
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001557:Benzenesulfonates / Q000138:chemical synthesis* / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010078:Oxazines / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001557:Benzenesulfonates; D010078:Oxazines