[Persistent trophoblastic tumor. Report of 15 cases at the National Institute of Perinatal Medicine].
Fifteen (18%) out of 83 patients with gestational trophoblastic disease, developed persistent trophoblastic tumor, from January, 1988 to March, 1994. Average age of patient was 25.5. There was antecedent of molar pregnancy in two cases. Beta fraction of chorionic gonadotrophin hormone at the time of diagnosis was 152,200 m UI/ml, average. During control it was in 80% of anovulatory oral cases. The treatment was based on metotrexate, and folinic acid; there was 100% remission. There was a total of 46.6% of pregnancies, after treatment; and 40% of them were normal.
Departamento de Oncología, Instituto Nacional de Perinatología, México, D.F.
J
J
Lira Plascencia
F
F
Tenorio González
A
A
Novoa Vargas
J
J
Gómezpedroso Rea
C
C
Aranda Flores
F
F
Ibargüengoitia Ochoa
D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D006063:Chorionic Gonadotropin / Q000032:analysis; D005260:Female; D005492:Folic Acid / Q000627:therapeutic use; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D008800:Mexico; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D018245:Trophoblastic Tumor, Placental Site / Q000737:chemistry / Q000188:drug therapy*
D000964:Antimetabolites, Antineoplastic; D006063:Chorionic Gonadotropin; D005492:Folic Acid; D008727:Methotrexate
Tumor trofoblástico persistente. Informe de 15 casos del Instituto Nacional de Perinatología.