Allogeneic BMT from a donor with fragile X syndrome: cytogenetic and molecular evaluation.
We report the first case of engraftment of bone marrow collected from a donor with Fragile X syndrome with subsequent cytogenetic and molecular evaluation. Engraftment was prompt and stable. Whilst the Fragile X abnormality could be detected initially by molecular techniques in the peripheral blood, it could not be detected cytogenetically while the patient was receiving CsA.
Department of Haematology and Bone Marrow Transplantation, Royal Brisbane Hospital, Herston, Queensland, Australia.
J
J
Morton
L
L
Arnold
B
B
Fletcher
C
C
McCarthy
J
J
Rowell
S
S
Durrant
D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics*; D006801:Humans; D008297:Male; D014019:Tissue Donors; D014184:Transplantation, Homologous; D014960:X Chromosome