Basal cell carcinoma: rapid techniques using cytokeratin markers to assist treatment by micrographic (Mohs') surgery.
In micrographic (Mohs') surgery, routine haematoxylin and eosin stains may present difficulties in interpretation of infiltrative (morphoeic) basal cell carcinoma. To supplement these routine stains rapid immunoperoxidase and immunofluorescence techniques are described using cytokeratin markers Dako LP34, MNF 116 or Novocastra NCL-Pan CK on frozen sections to help in the histological evaluation of these tumours.
Ramnarain
N D
ND
Department of Dermatopathology, St. John's Institute of Dermatology, St. Thomas' Hospital, London, England, UK.
Walker
N P
NP
Markey
A C
AC
D014408:Biomarkers, Tumor / Q000032:analysis*; D002280:Basal Cell Carcinoma / Q000601:surgery*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis*; D015580:Mohs Surgery / Q000379:methods*; D012878:Skin Neoplasms / Q000601:surgery*
D014408:Biomarkers, Tumor; D007633:Keratins