The influence of energy intake on the pathophysiology of Trypanosoma congolense infection in Scottish blackface sheep.
The intensity of parasitaemia, degree of anaemia, live body weight gains and blood biochemical changes were measured in two groups of Scottish Blackface sheep infected experimentally with Trypanosoma congolense and allowed either a high (9.9 MJ metabolisable energy (ME) day-1) or a low (6.1 MJ ME day-1) energy intake. It was observed that infected animals on the low energy intake had a longer mean prepatent period, but following patency they developed more severe anaemia and greater growth retardation than those on the high energy intake. Both infected groups exhibited significant reductions in serum total lipids, phospholipids, plasma cholesterol and albumin. However, these changes were more severe in the animals on the low energy intake than in those on the high energy intake. It was concluded that adequate energy nutrition enhances the ability of infected animals to withstand the adverse effects of infection, by promoting body weight gains and moderating the severity of the pathophysiological changes associated with ovine trypanosomosis.
University of Glasgow Veterinary School, Bearsden, UK.
E
E
Katunguka-Rwakishaya
J J
JJ
Parkins
G
G
Fishwick
M
M
Murray
P H
PH
Holmes
D000740:Anemia / Q000209:etiology / Q000662:veterinary; D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D002149:Energy Intake; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006128:Growth; D006454:Hemoglobins / Q000378:metabolism; D008297:Male; D009919:Orchiectomy; D010743:Phospholipids / Q000097:blood; D012709:Serum Albumin / Q000378:metabolism; D012756:Sheep; D012757:Sheep Diseases; D013997:Time Factors; D014280:Triglycerides / Q000097:blood; D014348:Trypanosoma congolense; D014353:Trypanosomiasis, African / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D014508:Urea / Q000097:blood
D001798:Blood Proteins; D005230:Fatty Acids, Nonesterified; D006454:Hemoglobins; D010743:Phospholipids; D012709:Serum Albumin; D014280:Triglycerides; D014508:Urea; D002784:Cholesterol