Comparison of DNA damage from genotoxicants using the microgel electrophoresis assay with primary cultures of rat and human hepatocytes.
Monteith
D K
DK
Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, MI 48105, USA.
Vanstone
J
J
D000818:Animals; D001564:Benzo(a)pyrene / Q000378:metabolism / Q000633:toxicity*; D001711:Biotransformation; D002478:Cells, Cultured; D003520:Cyclophosphamide / Q000633:toxicity*; D004249:DNA Damage; D004277:DNA, Single-Stranded / Q000187:drug effects*; D004587:Electrophoresis, Agar Gel; D005020:Ethyl Methanesulfonate / Q000633:toxicity*; D006801:Humans; D008099:Liver / Q000187:drug effects*; D008297:Male; D009153:Mutagens / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
D004277:DNA, Single-Stranded; D009153:Mutagens; D001564:Benzo(a)pyrene; D003520:Cyclophosphamide; D005020:Ethyl Methanesulfonate