[Pulmonary non-Hodgkin's lymphoma that arose in mucosa-associated lymphoid tissue of the salivary gland and was diagnosed at autopsy].
A 70-year-old woman complained of a dry mouth and swelling in the area of the left parotid gland for 6 years, and was admitted for evaluation of an abnormal shadow on chest X-ray film. She underwent a lip biopsy and a 99mTcO4- scintigram of the salivary gland, and Sjögren's syndrome was diagnosed. Histopathological examination of the percutaneous lung biopsy specimen showed pseudolymphoma, and examination of a specimen of the left parotid gland tumor showed myoepithelial sialadenitis. The patient died of respiratory failure due to a right pleural effusion 4 years later. Autopsy revealed pulmonary non-Hodgkin's lymphoma (diffuse, large, B cell, IgG) with monotonous infiltration of centrocyte-like cells. A retrospectively resected specimen of the left parotid gland tumor showed non-Hodgkin's lymphoma similar to that found in the autopsied lung. This patient probably had pulmonary non-Hodgkin's lymphoma that arose in mucosa-associated lymphoid tissue of the salivary gland and was associated with Sjögren's syndrome.
Kita
T
T
Department of Internal Medicine, Johana Kousei Hospital, Toyoma, Japan.
Fujimura
M
M
Hayase
M
M
Matsuda
T
T
Nonomura
A
A
D000368:Aged; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D016393:Lymphoma, B-Cell / Q000473:pathology*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000150:complications