[Draize test and alternative methods for evaluating irritation from chemical substances].
The eye irritancy test in rabbits (Draize test) is currently the method used to evaluate the hazard or safety of chemical substances. To reduce the need for animal testing some new procedures as alternative were elaborated. We present a review of method used as well as evaluation of sensitivity and repeatability of alternative tests applied in laboratories of European Economic Communities.
Zakładu Histologii i Embriologii AM w Warszawie.
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S
Moskalewski
E T
ET
Mystkowska
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E
Kiss
D000826:Animal Testing Alternatives; D000818:Animals; D005123:Eye / Q000187:drug effects*; D015386:Hazardous Substances / Q000633:toxicity*; D007509:Irritants / Q000633:toxicity*; D011817:Rabbits; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D015386:Hazardous Substances; D007509:Irritants
Test Draize' a i alternatywne metody oceny działania drazniacego substancji chemicznych.