[A rare mesenchymal tumor of the larynx . Case report and anatomo-clinical features].
Laryngeal chondrosarcoma is an uncommon mesenchymal tumor and in the world literature only 220 cases have been reported. We report in this retrospective examination three cases which age ranged from 54 to 65 years; one was a man and two were women. Two of the tumors arose in the thyroid cartilage, one in the cricoid cartilage. All the cases corresponded to low-grade, well-differentiated chondrosarcomas of the hyaline type (grade I) and two of the patients were alive and free from recurrence or metastasis after 6 and 12 years. One had a recurrence 5 years later with a superior histologic grade (grade II) and died 6 months after laryngectomy from metastatic disease. The AA. discusses the importance of assessing location, size, state of the resection borders, histologic grade and recurrence for the correct evaluation of the neoplasia, for therapeutic and prognostic purposes.
Cattedra di Istitituzioni di Anatomia e Istologia Patologia, Università di Catania.
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D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D002813:Chondrosarcoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D003413:Cricoid Cartilage / Q000737:chemistry / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D013957:Thyroid Cartilage / Q000473:pathology*
D014408:Biomarkers, Tumor
Su un raro tumore mesenchimale della laringe. Contributo casistico e rilievi anatomo-clinici.