Presurgical diagnosis of a primary carcinoid tumor of the thymus with MIBG.
A primary carcinoid tumor of the thymus showing ectopic ACTH syndrome was evaluated scintigraphically with four radiopharmaceuticals and a fluorescence method. Iodine-123-MIBG and 201Tl-Cl scintigraphy clearly demonstrated the tumor. Gallium-67-citrate and 99mTc(V)-DMSA showed no tumor uptake. The fluorescence method confirmed numerous storage granules of norepinephrine. Iodine-123-MIBG scintigraphy could be useful in the presurgical diagnosis of carcinoid tumors of the thymus.
Department of Nuclear Medicine, Gunma University School of Medicine, Japan.
T
T
Hirano
H
H
Otake
N
N
Watanabe
N
N
Oriuchi
A
A
Zennyouji
T
T
Fukuda
K
K
Endo
D019797:3-Iodobenzylguanidine; D000368:Aged; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002951:Citrates; D019343:Citric Acid; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008297:Male; D008856:Microscopy, Fluorescence; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D004113:Succimer; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D013794:Thallium Radioisotopes; D013950:Thymus Gland / Q000473:pathology; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery
D002951:Citrates; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D015609:Organotechnetium Compounds; D013794:Thallium Radioisotopes; D019343:Citric Acid; D019797:3-Iodobenzylguanidine; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D004113:Succimer