Cardiosympathetic neuropathy is independent of cardioparasympathetic neuropathy in patients with non-insulin-dependent diabetes mellitus.
The relationship between cardiosympathetic neuropathy and cardioparasympathetic neuropathy was investigated in 103 patients with non-insulin-dependent diabetes mellitus. Cardioparasympathetic nerve function was assessed by comparing electrocardiographically the expiratory and inspiratory R-R interval ratios, during a period of deep breathing, and the coefficients of variation of the R-R intervals. Cardiosympathetic nerve function was assessed by determining the uptake of [123I]metaiodobenzyl guanidine into the myocardium. The results indicate that there is no significant correlation between cardioparasympathetic and cardiosympathetic nerve function.
Okada
S
S
Third Department of Internal Medicine, Okayama University Medical School, Japan.
Tanokuchi
S
S
Higuchi
T
T
Ogino
Y
Y
Ichiki
K
K
Ishii
K
K
Hamada
H
H
Ota
Z
Z
Shimizu
M
M
Hiraki
Y
Y
D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000503:physiopathology*; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000294:innervation*; D006331:Heart Diseases / Q000503:physiopathology*; D006801:Humans; D008297:Male; D010275:Parasympathetic Nervous System / Q000503:physiopathology*; D012119:Respiration; D013564:Sympathetic Nervous System / Q000503:physiopathology*