[Surgical results of aortitis syndrome (Takayasu disease) combined with annuloaortic ectasia].
From March 1973 to December 1994, 8 patients (2 males and 6 females) aged 34.4 +/- 7.8 years, underwent composite graft replacement (CGR) for aortitis syndrome combined with annuloaortic ectasia (AAE) in our institute. Five patients showed active aortitis syndrome and steroid therapy was administrated to 2 of them. The mean value of the C-reactive protein (CRP) was 1.6 +/- 1.8 before the operation. The maximum diameter of the ascending aorta was 67.1 +/- 10.3 mm (range 53 to 85 mm). Stenosis and/or ectasia of the neck vessels were recognized in 5 cases, as well as the coronary artery in 2 cases. Isolated CGR was performed in 6 cases, and combined with single CABG to LAD in 1 case and with total arch replacement in 1 case. The enlarged ascending aorta was replaced with main graft using the exclusion method and interposed grafts for coronary arteries were sutured with pledgetted mattress sutures all around the coronary ostia. In patients with stenosis of neck vessels, oxygen saturation of the jugular vein was monitored during extracorporeal circulation for surveillance of cerebral ischemia. There was 1 early death due to pulmonary failure. Seven cases survived without any complications during 4-132 months (mean 83.4 months) of the follow-up period. After the operation, 3 cases required steroid therapy during 4-50 months. We concluded that preoperative control of active inflammation, selection of operative procedures, timing for the operation, and the long-term precise management of the intractable disease were essential for successful treatment of aortitis syndrome with AAE.
Department of Cardiovascular Surgery, Tokyo Women's Medical College, Japan.
H
H
Nakano
A
A
Hashimoto
S
S
Aomi
S
S
Nemoto
F
F
Yamaki
M
M
Kitamura
M
M
Hachida
H
H
Nishida
M
M
Endo
H
H
Koyanagi
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001022:Aortic Valve Insufficiency / Q000150:complications / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000379:methods*; D005112:Extracorporeal Circulation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013256:Steroids; D013625:Takayasu Arteritis / Q000150:complications / Q000601:surgery*
D000893:Anti-Inflammatory Agents; D013256:Steroids