[A complex antibiotic preparation obtained from a medicinal plant from the family Asteraceae].
Data of in vitro and in vivo investigations of antimicrobial activity of preparation K carried out both by the authors and by other researchers and pharmacological properties of this preparation have been summarized. Preparation K has been obtained from medicinal plant of the Asteraceae family. It is a natural composition of two antibiotics and of a number of minor compounds. The preparation possesses a wide spectrum of biological action. It is antimicrobially active against gram-positive bacteria, some species of gram-negative bacteria, fungi-dermatophytes including antibiotic-resistant strains. It is not toxic for animals, stimulates some defensive reactions of macroorganism, has immunomodulating, anti-inflammatory, anti-exudative, keratolytic properties. Preparation K is efficient for treatment of experimental mycoses of animals and is clinically tested as a local agent for treatment of dermatomycoses.
Smirnov
V V
VV
Bondarenko
A S
AS
Petrenko
G T
GT
Prikhod'ko
V A
VA
Evseenko
O V
OV
Pavlenko
L V
LV
D000818:Animals; D000904:Antibiotics, Antitubercular / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects; D006801:Humans; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use / Q000633:toxicity; D010946:Plants, Medicinal
D000904:Antibiotics, Antitubercular; D000935:Antifungal Agents; D010936:Plant Extracts; C018371:Preparation K
Kompleksnyĭ antibioticheskiĭ preparat, poluchennyĭ iz lekarstvennogo rasteniia semeĭstva Asteraceae.