Is this opioid analgesic tolerance?
Tolerance to the analgesic effect of opioids is a poorly understood phenomenon. While generally accepted to be an uncommon problem, it clearly can present major management difficulties in some patients. This case report illustrates different aspects of tolerance, describes a management approach using different opioids, and provides a focus for discussion of some current developments in understanding and managing this problem.
Fainsinger
R L
RL
Palliative Care Program, Edmonton General Hospital, Edmonton, Canada.
Bruera
E
E
D000368:Aged; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D004361:Drug Tolerance; D006801:Humans; D008297:Male; D010166:Palliative Care
D000701:Analgesics, Opioid