The pharmacokinetics and metabolism of SC-53228, a specific leukotriene B4 receptor antagonist.
Paulson
S
S
Searle Research and Development, Skokie, IL 60077, USA.
Readus
Y
Y
Bulik
S
S
Schoenhard
G
G
Stolzenbach
J
J
Fretland
D
D
D000284:Administration, Oral; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000378:metabolism* / Q000493:pharmacokinetics*; D001549:Benzamides / Q000008:administration & dosage / Q000378:metabolism* / Q000493:pharmacokinetics*; D001578:Benzopyrans / Q000008:administration & dosage / Q000378:metabolism* / Q000493:pharmacokinetics*; D001682:Biological Availability; D004285:Dogs; D006168:Guinea Pigs; D007275:Injections, Intravenous; D008252:Macaca fascicularis; D008253:Macaca mulatta; D008297:Male; D051381:Rats; D018102:Receptors, Leukotriene B4 / Q000037:antagonists & inhibitors*; D013045:Species Specificity
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001549:Benzamides; D001578:Benzopyrans; D018102:Receptors, Leukotriene B4; C082206:7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2H-1-benzopyran-2-propanoic acid