Fast anatomical imaging of the heart and assessment of myocardial perfusion with arrhythmia insensitive magnetization preparation.
A new contrast preparation based on modified driven equilibrium Fourier transfer is introduced and evaluated for generation of T1-weighted images for assessment of the myocardial perfusion with contrast agent first-pass kinetics. The new preparation scheme produces T1 contrast with insensitivity to arrhythmias in prospectively triggered sequential imaging thereby eliminating one of the major sources of problems in potential patient studies with previously employed contrast preparations schemes.
Tsekos
N V
NV
Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455, USA.
Zhang
Y
Y
Merkle
H
H
Wilke
N
N
Jerosch-Herold
M
M
Stillman
A
A
Uğurbil
K
K
D000465:Algorithms; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics; D003326:Coronary Circulation; D003327:Coronary Disease / Q000175:diagnosis; D004285:Dogs; D005583:Fourier Analysis; D005682:Gadolinium / Q000008:administration & dosage / Q000493:pharmacokinetics; D019786:Gadolinium DTPA; D006321:Heart / Q000033:anatomy & histology*; D006339:Heart Rate; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007700:Kinetics; D008279:Magnetic Resonance Imaging / Q000379:methods; D008863:Microspheres; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics; D004369:Pentetic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D011446:Prospective Studies; D016277:Ventricular Function, Left
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA