Episodic activation of the coagulation system in unstable angina does not elicit an acute phase reaction.
The results of our study suggest that the acute phase response may be partly related to a yet unknown primary inflammatory component in unstable angina. Further studies are needed to elucidate the actual role of inflammation in unstable angina and its relation to activation of the coagulation system.
Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy.
L M
LM
Biasucci
G
G
Liuzzo
G
G
Caligiuri
W
W
van de Greef
G
G
Quaranta
C
C
Monaco
A G
AG
Rebuzzi
C
C
Kluft
A
A
Maseri
D000210:Acute-Phase Reaction / Q000209:etiology* / Q000503:physiopathology*; D000328:Adult; D000368:Aged; D000789:Angina, Unstable / Q000150:complications* / Q000503:physiopathology*; D000990:Antithrombin III / Q000378:metabolism* / Q000502:physiology; D001777:Blood Coagulation / Q000502:physiology*; D002097:C-Reactive Protein / Q000378:metabolism* / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism* / Q000502:physiology; D011516:Prothrombin / Q000378:metabolism*
D010446:Peptide Fragments; C046193:antithrombin III-protease complex; C045879:prothrombin fragment 1.2; D000990:Antithrombin III; D011516:Prothrombin; D002097:C-Reactive Protein; D010447:Peptide Hydrolases