Cyproheptadine-induced central anticholinergic syndrome in a child: a case report.
A 16-year-old female patient presented to our emergency department with anticholinergic psychosis after an ingestion of cyproheptadine. The central anticholinergic syndrome occurs frequently but often goes unrecognized because many patients do not fit into a well defined clinical pattern. The diagnosis depends on the suspicion and recognition of the psychiatric manifestations, including agitation, confusion, and hallucinations. A high index of suspicion is necessary in children in particular, since central effects seem to predominate in many anticholinergic overdoses.
Blaustein
B S
BS
Department of Emergency Medicine, St. Barnabas Hospital, Bronx, New York 10457, USA.
Gaeta
T J
TJ
Balentine
J R
JR
Gindi
M
M
D000293:Adolescent; D018680:Cholinergic Antagonists / Q000506:poisoning* / Q000627:therapeutic use; D003221:Confusion / Q000139:chemically induced; D003533:Cyproheptadine / Q000506:poisoning* / Q000627:therapeutic use; D062787:Drug Overdose; D001068:Feeding and Eating Disorders / Q000188:drug therapy; D005260:Female; D006212:Hallucinations / Q000139:chemically induced; D006801:Humans; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D013577:Syndrome
D018680:Cholinergic Antagonists; D003533:Cyproheptadine