Human T-cell leukemia virus type II infection among high risk groups and its influence on HIV-1 disease progression.
The prevalence and the risk factors of the human T-cell leukemia virus type I/II (HTLV-I/II) infection were evaluated among 552 individuals at high risk for HIV-1. HTLV infections showed a low (1.6%) prevalence, were restricted to intravenous drug addicts and were due to HTLV-II alone. Moreover, in order to weigh the influence of HTLV-II on the natural history of HIV-1 infection, the clinical outcome of HIV-1 disease was compared between subjects with and without HTLV-II coinfection. Our findings showed that HTLV-II does not adversely affect the outcome of HIV-1 infection. Infact, a slower disease progression has been recorded in some HTLV-II coinfected subjects.
Cattedra di Malattie Infettive, Università degli Studi di Parma, Italy.
M
M
Giacomo
E G
EG
Franco
C
C
Claudio
C
C
Carlo
D A
DA
Anna
D
D
Anna
F
F
Franco
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000503:physiopathology; D000328:Adult; D015897:Comorbidity; D004279:DNA, Viral / Q000032:analysis; D015480:Deltaretrovirus Antibodies / Q000097:blood; D018450:Disease Progression; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000453:epidemiology* / Q000503:physiopathology; D015497:HIV-1 / Q000235:genetics / Q000276:immunology; D015491:HTLV-II Infections / Q000453:epidemiology* / Q000503:physiopathology; D006716:Homosexuality / Q000706:statistics & numerical data; D015367:Human T-lymphotropic virus 2 / Q000235:genetics / Q000276:immunology; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D015819:Substance Abuse, Intravenous / Q000453:epidemiology; D015996:Survival Rate; D016176:T-Lymphocyte Subsets / Q000473:pathology
D004279:DNA, Viral; D015480:Deltaretrovirus Antibodies; D015483:HIV Antibodies