Malignant degeneration of a mature cystic teratoma five decades after discovery.
Malignant degeneration of mature cystic teratomas has been reported in 1-3% of cases. A patient with the unusual occurrence of a stage IIIC squamous cell carcinoma arising in a mature teratoma over 50 years after initial diagnosis is presented. The patient was treated with pelvic radiotherapy. The role of serum squamous cell carcinoma antigen in detecting degeneration of mature cystic teratomas at an early stage is considered.
Griffiths
D
D
Department of Obstetrics and Gynecology, Indiana University Medical Center, Indianapolis 46202, USA.
Wass
J
J
Look
K
K
Sutton
G
G
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D013724:Teratoma / Q000000981:diagnostic imaging / Q000473:pathology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed