Isradipine, a calcium-channel antagonist, has immunosuppressor activity on T lymphocytes from peripheral blood and synovial fluid from patients with autoimmune arthritis.
Servicio de Enfermedades del Sistema Immune, Hospital Universitario Príncipe de Asturias, Spain.
C
C
Guillen
A
A
Prieto
M
M
Alvarez De Buergo
L
L
Villa
H
H
Rico
A
A
Zea
M P
MP
Hernandez
M
M
Alvarez-Mon
D001168:Arthritis / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D001327:Autoimmune Diseases / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D002121:Calcium Channel Blockers / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D017275:Isradipine / Q000494:pharmacology* / Q000627:therapeutic use; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D013582:Synovial Fluid / Q000187:drug effects / Q000276:immunology*; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology
D002121:Calcium Channel Blockers; D007166:Immunosuppressive Agents; D017275:Isradipine