A receptor kinase-like protein encoded by the rice disease resistance gene, Xa21.
The rice Xa21 gene, which confers resistance to Xanthomonas oryzae pv. oryzae race 6, was isolated by positional cloning. Fifty transgenic rice plants carrying the cloned Xa21 gene display high levels of resistance to the pathogen. The sequence of the predicted protein, which carries both a leucine-rich repeat motif and a serine-threonine kinase-like domain, suggests a role in cell surface recognition of a pathogen ligand and subsequent activation of an intracellular defense response. Characterization of Xa21 should facilitate understanding of plant disease resistance and lead to engineered resistance in rice.
Song
W Y
WY
Department of Plant Pathology, University of California, Davis 95616, USA.
Wang
G L
GL
Chen
L L
LL
Kim
H S
HS
Pi
L Y
LY
Holsten
T
T
Gardner
J
J
Wang
B
B
Zhai
W X
WX
Zhu
L H
LH
Fauquet
C
C
Ronald
P
P
D000595:Amino Acid Sequence; D003001:Cloning, Molecular; D017343:Genes, Plant; D008040:Genetic Linkage; D008969:Molecular Sequence Data; D012275:Oryza / Q000201:enzymology / Q000235:genetics* / Q000382:microbiology; D010935:Plant Diseases; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D030821:Plants, Genetically Modified; D017346:Protein Serine-Threonine Kinases / Q000235:genetics* / Q000378:metabolism; D020794:Receptor Protein-Tyrosine Kinases; D011956:Receptors, Cell Surface / Q000235:genetics* / Q000378:metabolism; D014974:Xanthomonas / Q000502:physiology
D010940:Plant Proteins; D011956:Receptors, Cell Surface; C097148:Xa21 protein, Oryza sativa; D020794:Receptor Protein-Tyrosine Kinases; D017346:Protein Serine-Threonine Kinases