[Mycobacterium kansasii infection in patients with human immunodeficiency virus infection].
We report a retrospective study of 12 caucasian men infected with HIV who had developed Mycobacterium kansasii infection (Mk). All patients had a low blood lymphocyte CD4 count (1-130, mean 15/mm3) and ten met the diagnostic criteria for AIDS. The 12 patients had pulmonary symptoms (dyspnea, cough) and fever. On chest X-ray, nodular, interstitial or diffuse parenchymal infiltrates, mediastinal and hilar adenopathies were observed. Two patients had pleural effusion, but none had cavitary lung disease. Mk was isolated by culture of sputum (n = 7), blood (n = 3), bronchial biopsy (n = 2) or bone marrow (n = 1). No patient had clinical extra-pulmonary disease. Survival after diagnosis was in average 7 months. Potential for therapeutic response is reviewed and documented.
Service de médecine interne, Hôpital Robert-Ballanger, Aulnay-sous-Bois, France.
P
P
Boudon
M P
MP
Le Pennec
D
D
Malbec
M
M
Mathieu
J L
JL
Slama
P
P
Manet
E
E
Pines
S
S
Kretz
T
T
Giacomini
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000401:mortality; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000209:etiology* / Q000401:mortality; D012189:Retrospective Studies; D013997:Time Factors
D000995:Antitubercular Agents
Infection à Mycobacterium kansasii chez des patients infectés par le virus de l'immunodéficience humaine.