[Morphologic analysis of arrhythmogenic and non-arrhythmogenic zones of subendocardial areas of the heart in patients with rhythm disorders].
The signs of cardiomyocyte (CMC) apoptotic degeneration which is not specific for well differentiated heart tissue were found in both arrhythmogenic and non-arrhythmogenic subendocardial zones. Contracted and over contracted CMC with characteristic ultrastructure and damaged inserted discs as well as atrophic CMC and cells with apoptotic degeneration were observed in the arrhythmogenic heart zones. These changes amy play a role in the genesis of rhythm disturbances.
Bokeriiai
L A
LA
Beskrovnova
N N
NN
Tsyplenkova
V G
VG
Golukhova
E Z
EZ
Beskrovnova
F V
FV
D000328:Adult; D017209:Apoptosis; D001145:Arrhythmias, Cardiac / Q000473:pathology*; D002454:Cell Differentiation; D004699:Endocardium / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009133:Muscular Atrophy / Q000473:pathology; D009200:Myocardial Contraction; D012016:Reference Values
Morfologicheskiĭ analiz aritmogennykh i nearitmogennykh zon subéndokardial'nykh otdelov serdtsa u bol'nykh s narusheniiami ritma.