Prevalence of Candida ciferrii in elderly patients with trophic disorders of the legs.
In order to define the prevalence of Candida ciferrii in onychomycosis, the fungal biota associated with toe nail onyxis was examined in 50 elderly patients with trophic disorders of the legs and in 220 patients without clinical evidence of trophic disorders. Candida ciferrii was more frequent in the first group of patients since it was recovered from 24% of these patients, whereas its prevalence was only 1.4% in the control group. Moreover, the positivity of the direct examination of toe nail scrapings, the absence of any other associated pathogens, and the repeated isolation of this yeast species for some of the patients confirmed its pathogenicity.
Laboratoire de Parasitologie-Mycologie, CHU, Angers, France.
L
L
de Gentile
J P
JP
Bouchara
C
C
Le Clec'h
B
B
Cimon
F
F
Symoens
D
D
Chabasse
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000494:pharmacology; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification* / Q000378:metabolism; D002177:Candidiasis / Q000150:complications* / Q000382:microbiology; D005533:Foot Dermatoses / Q000150:complications / Q000382:microbiology; D006801:Humans; D007866:Leg / Q000098:blood supply; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009262:Nails / Q000382:microbiology*; D014009:Onychomycosis / Q000150:complications* / Q000382:microbiology; D010084:Oxidation-Reduction; D016491:Peripheral Vascular Diseases / Q000150:complications*; D011446:Prospective Studies; D013778:Tetrazolium Salts / Q000378:metabolism; D014034:Toes
D000935:Antifungal Agents; D013778:Tetrazolium Salts; C009591:triphenyltetrazolium