A comparative study on Langerhans cells in lymph nodes with dermatopathic lymphadenopathy and histiocytosis X cells.
It was elucidated that the majority of DC were LC which were positive for CD 1a, but negative for PCNA, and possessed BG in the lymph nodes with DPL. On the other hand, HCX cells were almost always positive for PCNA. From this point of view, it can be speculated that LC in the lymph nodes of the DPL are non dividing mature cells and migrate from the skin lesion. HCX cells which were positive for CD 4 may be more immature cells than LC in DPL, and may be pathological cells which can divide in the foci.
Shamoto
M
M
Division of Pathological Cytology, Fujita Health University School of Medicine, Aichi, Japan.
Osada
A
A
Shinzato
M
M
Kaneko
C
C
Shimizu
M
M
D018949:Antigens, CD1 / Q000378:metabolism; D015704:CD4 Antigens / Q000378:metabolism; D006646:Histiocytosis, Langerhans-Cell / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007801:Langerhans Cells / Q000276:immunology / Q000473:pathology*; D008198:Lymph Nodes / Q000276:immunology / Q000473:pathology*; D008206:Lymphatic Diseases / Q000276:immunology / Q000473:pathology*; D018809:Proliferating Cell Nuclear Antigen / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism
D018949:Antigens, CD1; D015704:CD4 Antigens; D018809:Proliferating Cell Nuclear Antigen; D009418:S100 Proteins