[The characteristics of new species of pathogenic microorganisms in the genus Francisella].
The comparative study of newly discovered pathogenic bacteria of the genus Francisella was carried out with the use of a complex of microbiological and serological methods. While having great similarity to the causative agent of tularemia, F. novicida, F. novicida-like bacteria and F. philomiragia had lesser growth requirements, some specific morphological and structural features, were capable of fermenting sucrose and exhibited low pathogenicity to experimental animals. The strains under study proved to be virulent with regard to golden hamsters, who were for this reason proposed as an adequate model for the isolation of these bacteria from environmental objects and pathological material obtained from patients. The use of immunoblotting made it possible to find out that all Francisella species had protein antigens, similar to their electrophoretic mobility and serological activity.
I S
IS
Meshcheriakova
M I
MI
Kormilitsyna
I V
IV
Rodionova
N D
ND
Konstantinova
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis; D006224:Cricetinae; D005603:Francisella / Q000145:classification* / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity / Q000648:ultrastructure; D005604:Francisella tularensis / Q000145:classification; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology; D006168:Guinea Pigs; D006801:Humans; D008647:Mesocricetus; D051379:Mice; D008854:Microscopy, Electron; D011817:Rabbits; D013987:Ticks / Q000382:microbiology; D014406:Tularemia / Q000382:microbiology; D014774:Virulence; D014871:Water Microbiology
D000942:Antigens, Bacterial
Kharakteristika novykh vidov patogennykh mikroorganizmov roda Francisella.