Diagnostic methods of early detection of endometrial hyperplasia and cancer.
Endometrial carcinoma is the most frequent genital neoplasia in women. Our own experience is based on a group of 3310 patients who were studied between 1985 and April 1994. In 2148 cases, equivalent to 56.4%, hysteroscopy was performed because of the presence of abnormal uterine bleeding (AUB). We found 672 endometrial hyperplasia (601 low risk-71 high risk) and 93 endometrial carcinoma. According to our experience we can assert that: hysteroscopy allows the measurement of the extension of the intracavitary neoplastic pathology and the definition of its topographic map; it is the only method that allows a target biopsy; it facilitates the evaluation of the extension of the neoplasia in the cervical canal, with the help of a deep biopsy into the cervical tissue (as proposed by La Sala) increasing its diagnostic accuracy.
2nd Department of Obstetrics e Gynecology, Rome University La Sapienza, Italy.
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Pace
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Grassi
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Ferrero
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Figliolini
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Catania
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Labi
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Pachì
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Figliolini
D000368:Aged; D001706:Biopsy; D004107:Dilatation and Curettage; D004714:Endometrial Hyperplasia / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D015994:Incidence; D008403:Mass Screening; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate