Jacalin, a lectin interacting with O-linked sugars and mediating protection of CD4+ cells against HIV-1, binds to the external envelope glycoprotein gp120.
Centre de Tri des Molécules anti-HIV, CNRS UPR9008, INSERM U249, Montpellier, France.
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Corbeau
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Pasquali
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Devaux
D000998:Antiviral Agents / Q000737:chemistry*; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects / Q000276:immunology* / Q000821:virology; D002241:Carbohydrates / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D015699:HIV Envelope Protein gp120 / Q000737:chemistry*; D015497:HIV-1 / Q000187:drug effects / Q000276:immunology*; D006801:Humans; D037102:Lectins / Q000737:chemistry*; D037121:Plant Lectins; D011485:Protein Binding / Q000276:immunology
D000998:Antiviral Agents; D002241:Carbohydrates; D015699:HIV Envelope Protein gp120; D037102:Lectins; D037121:Plant Lectins; C043696:jacalin