Protection of goats against rinderpest by vaccination with attenuated peste des petits ruminants virus.
The ability of the attenuated peste des petits ruminants vaccine virus to protect small ruminants against virulent rinderpest virus was investigated. Out of four susceptible goats that were infected with the highly virulent Saudi strain of rinderpest virus by intranasal ioculation, three developed mild clinical signs of disease and infected susceptible in-contact goats and cattle with rinderpest virus. However, four goats which had been vaccinated with the attenuated peste des petits ruminants virus resisted challenge with virulent rinderpest virus and did not infect susceptible in-contact animals.
Couacy-Hymann
E
E
CIRAD-EMVT, France.
Bidjeh
K
K
Angba
A
A
Domenech
J
J
Diallo
A
A
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D002522:Chlorocebus aethiops; D004198:Disease Susceptibility; D015511:Goat Diseases; D006041:Goats; D008297:Male; D018103:Morbillivirus / Q000276:immunology* / Q000472:pathogenicity; D009500:Neutralization Tests; D012301:Rinderpest / Q000276:immunology / Q000517:prevention & control* / Q000635:transmission; D014611:Vaccination / Q000662:veterinary*; D014613:Vaccines, Attenuated; D014709:Vero Cells; D014765:Viral Vaccines; D014774:Virulence
D000914:Antibodies, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines