[Autoregressive analysis of variability in heart rate and blood pressure in asthmatic children--difference of severity].
Changes in ECG R-R intervals and blood pressure (lye and stand) were assessed by the autoregressive power spectral analysis method in 40 asthmatic children (age range: 2-16 years, mean +/- SD: 9.4 +/- 4.1 years). Significantly lower low frequency (LF: < or = 0.1 cycle/beat) power and high frequency (HF: 0.1-0.5 cycle/beat) power of R-R intervals were detected in severe type. LF fluctuations in R-R intervals are known to be mediated by the parasympathetic nervous system and the beta-adrenergic nervous system, while HF fluctuations in R-R intervals are mediated by the parasympathetic nervous system, LF fluctuations in systolic blood pressure by the alpha-adrenergic nervous system. The results suggested parasympathetic nervous system disorder especially in severe asthmatic children. Thus, spectral analysis of variability in R-R intervals and blood pressure are a useful tool for quantifying autonomic nervous system activity.
Department of Pediatrics, Oita Medical University.
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Korematsu
D000293:Adolescent; D001249:Asthma / Q000150:complications / Q000503:physiopathology*; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis / Q000209:etiology; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D010275:Parasympathetic Nervous System / Q000503:physiopathology*; D012044:Regression Analysis; D012720:Severity of Illness Index