[Surgical treatment of adenocarcinoma of the stomach: 1969-1994. Apropos of 261 cases].
The study concerned 261 cases of gastric adenocarcinoma operated on between 1969 and 1994. Clinical, histological and therapeutic features were analyzed and compared during 3 periods (Group 1: 1969-78, Group 2: 1979-88, Group 3: 1989-94). The aim was to evaluate changes and results occurred in gastric carcinoma. The median age was 65 years (rage 25-90 years), the sex ratio, 1.9. The most common location was in the lower third of the stomach and the cancer was often far-advanced (73 percent of stages III and IV). Subtotal gastrectomy was replaced by total gastrectomy; the number of distal gastrectomy was unchanged. Large lymph node dissection was systematically performed in group 3. Curative resection rate increased from 28 to 51 percent between group 1 and group 3. Despite the more radical surgery, morbidity and post operative mortality rates decreased (respectively: 44.5%, 33%, 25.4%, and 22%, 10%, 7.2% for the groups 1, 2, 3, p < 0.01). 2-year survival rates were 20 percent for group 1, 25 percent for group 2 and 32 percent for group 3 (p < 0.01). This rates can be considered as satisfying in view of the high rate of III and IV stages.
Meyer
C
C
Service de Chirurgie Générale et Digestive, Hôpital de Hautepierre, CHU de Strasbourg.
Perraud
V
V
Rohr
S
S
De Manzini
N
N
Thiry
L C
LC
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004724:Endoscopy; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
Le traitement chirurgical de l'adénocarcinome de l'estomac: évolution de 1969 à 1994. A propos de 261 cas.