Deoxyspergualin is synergistic with cyclosporin A, but not with FK506 in a rat heart allograft transplantation model.
Bersztel
A
A
Department of Transplantation Surgery, University Hospital, Uppsala, Sweden.
Wanders
A
A
Wadström
J
J
Ekberg
H
H
Olausson
M
M
Tufveson
G
G
Gannedahl
G
G
D000818:Animals; D016572:Cyclosporine / Q000008:administration & dosage* / Q000633:toxicity; D004347:Drug Interactions; D004357:Drug Synergism; D006146:Guanidines / Q000008:administration & dosage* / Q000633:toxicity; D016027:Heart Transplantation / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000633:toxicity; D008297:Male; D051381:Rats; D011921:Rats, Inbred WKY; D016559:Tacrolimus / Q000008:administration & dosage* / Q000633:toxicity; D014184:Transplantation, Homologous
D006146:Guanidines; D007166:Immunosuppressive Agents; D016572:Cyclosporine; C037258:gusperimus; D016559:Tacrolimus