[The function of the reproductive system in x-ray-irradiated male rats after the transplantation of a culture of testicular cells from newborn piglets].
The effect exerted by transplantation of the 5 day culture of testicles from newly born piglets on the hypogonadal state of mature X-ray irradiated (3 Gy) rats was studied. It has been found that a month after transplantation (two months after irradiation) the hypogonadal state disappeared for a while, which is confirmed by normalization of the weight of seminal vesicles, content of testosterone and biologically active lutropine, restoration of the reproductive function of rats. No significant changes in steroidogenesis activity have been found, which proves a substituent character of transplantation. The effect disappears three months later but certain restoration of the content of nucleic acids in the testicles is observed.
Varha
S V
SV
Reznikov
O H
OH
Turchyn
I S
IS
Demchenko
V M
VM
Potikha
O P
OP
Sinitsyn
P V
PV
Tarasenko
L V
LV
Chaĭkovs'ka
L V
LV
D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism / Q000528:radiation effects; D000818:Animals; D000831:Animals, Newborn; D002478:Cells, Cultured; D004247:DNA / Q000378:metabolism / Q000528:radiation effects; D007986:Luteinizing Hormone / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D012313:RNA / Q000378:metabolism / Q000528:radiation effects; D051381:Rats; D012098:Reproduction / Q000502:physiology / Q000528:radiation effects*; D013552:Swine; D013737:Testis / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects* / Q000637:transplantation*; D013739:Testosterone / Q000378:metabolism / Q000528:radiation effects; D013997:Time Factors; D014183:Transplantation, Heterologous
D013739:Testosterone; D012313:RNA; D007986:Luteinizing Hormone; D004247:DNA; D015096:3-Hydroxysteroid Dehydrogenases
Stan reproduktyvnoï systemy u renthenoprominenykh samtsiv shchuriv pislia transplantatsiï kul'tury klityn sim'ianykiv novonarodzhenykh porosiat.