Noninfectious inflammatory response to gold weight eyelid implants.
We describe three patients with noninfectious inflammatory reactions to gold weight eyelid implants, a complication not previously reported. Eyelid edema and erythema developed gradually in each patient, and maximal inflammation that prompted treatment was present at 12, 3, and 5 weeks, respectively, after surgery in the three patients. Management involved removal of the implant in the first patient, oral corticosteroids followed by replacement of the implant by a platinum weight in the second patient, and a local corticosteroid injection with retention of the implant in the third. Histopathological features included a thick eosinophilic coagulum at the tissue-gold interface and an intense, predominantly lymphocytic infiltrate in the collagenous capsule that surrounded the implants. Gold weight eyelid implants can elicit a gradually progressive inflammatory response. In at least some cases, local corticosteroid injection may suppress the inflammation and permit retention of the implant.
Bair
R L
RL
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee 53226, USA.
Harris
G J
GJ
Lyon
D B
DB
Komorowski
R A
RA
D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001762:Blepharitis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D004487:Edema / Q000209:etiology / Q000473:pathology / Q000628:therapy; D004890:Erythema / Q000209:etiology / Q000473:pathology / Q000628:therapy; D005141:Eyelid Diseases / Q000209:etiology / Q000473:pathology / Q000628:therapy; D005143:Eyelids / Q000601:surgery; D005158:Facial Paralysis / Q000150:complications; D005260:Female; D006046:Gold / Q000009:adverse effects*; D006801:Humans; D007634:Keratitis / Q000209:etiology / Q000517:prevention & control; D008875:Middle Aged; D019736:Prostheses and Implants / Q000009:adverse effects*; D012086:Reoperation; D013256:Steroids
D000893:Anti-Inflammatory Agents; D013256:Steroids; D006046:Gold