Long survival after splenic immunoblastic transformation of Waldenström's macroglobulinaemia.
Immunoblastic transformation of Waldenström's macroglobulinaemia is normally a preterminal event. We report a case in which the immunoblastic transformation appeared to be limited to the spleen. Splenectomy was more effective than cytotoxic chemotherapy in controlling the disease, and the patient remains free of disease 45 months later.
Department of Haematology, Alexandra Hospital, Redditch.
A J
AJ
Winter
D
D
Obeid
E L
EL
Jones
D006801:Humans; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D013156:Splenectomy; D013163:Splenomegaly / Q000209:etiology / Q000601:surgery; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*