Isolated cerebral thrombo-embolism and Crohn disease.
Arterial thrombo-embolism is an unusual complication in inflammatory bowel disease in adults and children. Cerebral arterial disease has been reported on only a few occasions. There are only two previous case reports of arterial disease occurring in a child with Crohn disease. However in both instances the arterial disease was part of a generalised Takayasu arteritis which resulted in multi-organ involvement. This report describes a 14-year-old boy who developed seizures before a histological diagnosis of Crohn disease was made. These seizures were the result of a vascular lesion which was confined to the right middle cerebral artery. CONCLUSION. Crohn disease as well as ulcerative colitis should be considered as a possible cause of cerebrovascular accidents in children.
Department of Paediatrics, University College Dublin, Ireland.
S M
SM
Gormally
W
W
Bourke
B
B
Kierse
H
H
Monaghan
J
J
McMenamin
B
B
Drumm
D000293:Adolescent; D001706:Biopsy; D002533:Cerebral Angiography; D003424:Crohn Disease / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology*; D008297:Male