Spontaneous intracranial hypotension from a CSF leak in a patient with Marfan's syndrome.
A patient with Marfan's syndrome had spontaneous intracranial hypotension secondary to a proved CSF leak. It is postulated that the leak was caused by minor, unrecognised trauma rupturing spinal arachnoid diverticula. The diverticula were probably pre-existing abnormalities complicating the Marfan's syndrome. It is concluded that patients with spinal meningeal defects may be at increased risk of developing CSF leaks, possibly secondary to unrecognised trauma.
Davenport
R J
RJ
University of Edinburgh, Department of Clinical Neurosciences, Western General Hospital, Scotland.
Chataway
S J
SJ
Warlow
C P
CP
D000293:Adolescent; D002555:Cerebrospinal Fluid; D005260:Female; D006801:Humans; D007024:Hypotension, Orthostatic / Q000209:etiology* / Q000503:physiopathology; D007427:Intracranial Pressure; D008382:Marfan Syndrome / Q000150:complications* / Q000503:physiopathology; D009192:Myelography; D013346:Subarachnoid Space / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed