Insulin-like growth factor-I and angiographically documented coronary artery disease.
In conclusion, we have reported an association between low IGF-I concentrations and CAD in relatively young men. This observation raises the possibility that IGF-I deficiency could be part of the polymetabolic syndrome. Whether a subnormal IGF-I production is due to growth hormone secretory abnormalities or to other metabolic reasons (e.g., insulin resistance or fat distribution, or both) is still unknown.
Department of Internal Medicine, University of Genoa, Italy.
P
P
Spallarossa
C
C
Brunelli
F
F
Minuto
D
D
Caruso
M
M
Battistini
S
S
Caponnetto
R
R
Cordera
D000328:Adult; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood* / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D007334:Insulin-Like Growth Factor I