Intraoperative identification of parathyroid gland pathology: a new approach.
Technetium 99m-sestamibi, a radiopharmaceutical used for the diagnostic imaging of abnormal parathyroid tissue, and the Neoprobe 1000, a hand-held, gamma-detecting probe, were used concurrently, during surgical exploration, in three children with hyperparathyroidism. This novel combination assisted with the identification of an ectopic mediastinal parathyroid adenoma and with the localization of multiple hyperplastic parathyroid glands. 99mTc-sestamibi combined with the Neoprobe 1000 may prove to be a useful adjunctive technique for the intraoperative localization of abnormal parathyroid tissue in selected patients.
Department of Surgery, Ohio State University College of Medicine, Columbus, USA.
D A
DA
Martinez
D R
DR
King
C
C
Romshe
R A
RA
Lozano
J D
JD
Morris
M S
MS
O'Dorisio
E
E
Martin
D000236:Adenoma / Q000000981:diagnostic imaging* / Q000601:surgery*; D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007432:Intraoperative Period; D008297:Male; D010280:Parathyroid Glands / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi
D017256:Technetium Tc 99m Sestamibi