Spontaneous intracranial hypotension from a CSF leak in a patient with Marfan's syndrome.
A patient with Marfan's syndrome had spontaneous intracranial hypotension secondary to a proved CSF leak. It is postulated that the leak was caused by minor, unrecognised trauma rupturing spinal arachnoid diverticula. The diverticula were probably pre-existing abnormalities complicating the Marfan's syndrome. It is concluded that patients with spinal meningeal defects may be at increased risk of developing CSF leaks, possibly secondary to unrecognised trauma.
University of Edinburgh, Department of Clinical Neurosciences, Western General Hospital, Scotland.
R J
RJ
Davenport
S J
SJ
Chataway
C P
CP
Warlow
D000293:Adolescent; D002555:Cerebrospinal Fluid; D005260:Female; D006801:Humans; D007024:Hypotension, Orthostatic / Q000209:etiology* / Q000503:physiopathology; D007427:Intracranial Pressure; D008382:Marfan Syndrome / Q000150:complications* / Q000503:physiopathology; D009192:Myelography; D013346:Subarachnoid Space / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed