Comparison of nylon and polypropylene sutures in a microvenous thrombosis model.
Thrombosis rates of femoral end-to-end microvenous anastomoses with nylon and polypropylene sutures (9-0 suture, 70 mu needle) were compared in a microvenous thrombosis model. The vessel injuries were produced during anastomosis by using a suture with a knot 1 cm from the needle. Anastomotic thrombosis rates were assessed by visual inspection and strip test at 24 hr postoperatively. Low thrombosis rates (0% and 20%, respectively) of anastomoses with both unknotted nylon and unknotted polypropylene sutures were obtained. Anastomoses with knotted nylon and polypropylene sutures resulted in 65% and 45% thrombosis rates, respectively. Statistical analyses showed that there were no significant differences between thrombosis rates, both in anastomosis performance with unknotted nylon and polypropylene sutures (P > 0.05) and with knotted nylon and polypropylene sutures (P > 0.05), while there were significant differences between the thrombosis rate using unknotted sutures and knotted sutures (P < 0.01). It was concluded that vascular injury, not suture material, is the main factor leading to thrombosis in this model.
Ustüner
T E
TE
Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, CA 94305, USA.
Zhang
F
F
Lineaweaver
W C
WC
D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D005268:Femoral Vein / Q000293:injuries / Q000473:pathology; D006083:Graft Occlusion, Vascular / Q000209:etiology*; D008297:Male; D009757:Nylons; D011126:Polypropylenes; D051381:Rats; D017207:Rats, Sprague-Dawley; D013536:Suture Techniques; D013537:Sutures; D013927:Thrombosis / Q000209:etiology*; D013997:Time Factors
D009757:Nylons; D011126:Polypropylenes