The influence of adjuvants on oral vaccination of chickens against Newcastle disease.
Living V4 strain Newcastle disease vaccine was given to chickens orally. The inclusion of DEAE-dextran, Quil-A or TiterMax in the vaccine, or delivering the vaccine as Iscoms, did not enhance the serological response. The immediate serological response to living V4 vaccine was enhanced in the presence of Avridine. Chickens produced a low serological response to oral administration of inactivated V4 vaccine. This response was not enhanced in the presence of Avridine.
Department of Veterinary Pathology, University of Queensland, Brisbane, Australia.
S F
SF
Rehmani
P B
PB
Spradbrow
D000276:Adjuvants, Immunologic; D000284:Administration, Oral; D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D000917:Antibody Formation; D002642:Chick Embryo; D002645:Chickens; D003637:DEAE-Dextran; D006385:Hemagglutination Inhibition Tests; D009521:Newcastle Disease / Q000276:immunology* / Q000517:prevention & control; D009522:Newcastle disease virus / Q000254:growth & development / Q000276:immunology*; D011060:Poloxalene; D062605:Quillaja Saponins; D012503:Saponins; D015164:Vaccines, Inactivated / Q000008:administration & dosage*; D014765:Viral Vaccines / Q000008:administration & dosage*
D000276:Adjuvants, Immunologic; D000914:Antibodies, Viral; D062605:Quillaja Saponins; D012503:Saponins; D015164:Vaccines, Inactivated; D014765:Viral Vaccines; C086752:TiterMax; C046386:Quil A; D011060:Poloxalene; D003637:DEAE-Dextran