Stage T1c prostate cancer: perspectives on clinical management.
Nonpalpable prostate cancer, detected on a biopsy sample and prompted by an elevated prostate-specific antigen level, has become one of the most common presentations of the disease. The clinical significance of these cancers has been debated, but pathologic examination has shown a substantial tumor volume in most patients. On the other hand, a tumor is confined within the surgical margins in some 80% of men undergoing radical prostatectomy for T1c cancers. Overall, then, most T1c prostate cancers meet the desired selection criteria for radical prostatectomy, which include a tumor of clinical significance, yet one which can be totally excised surgically.
Department of Urology, Vanderbilt University Medical Center, Nashville, TN 37232-2765, USA.
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Smith
D001707:Biopsy, Needle; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D018579:Patient Selection; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000276:immunology / Q000473:pathology / Q000601:surgery*; D011788:Quality of Life; D016896:Treatment Outcome
D017430:Prostate-Specific Antigen