Mouse T-cell receptor variable gene segment families.
All mouse T-cell receptor alpha/delta, beta, and gamma variable (Tcra/d-, b-, and g-V) gene segments were aligned to compare the sequences with one another, to group them into subfamilies, and to derive a name which complies with the standard nomenclature. It was necessary to change the names of some V gene segments because they conflicted with those of other segments. The traditional classification into subfamilies was re-evaluated using a much larger pool of sequences. In the mouse, most V gene segments can be grouped into subfamilies of closely related genes with significantly less similarity between different subfamilies.
Paul-Ehrlich-Institute, Langen, Germany.
B
B
Arden
S P
SP
Clark
D
D
Kabelitz
T W
TW
Mak
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D051379:Mice; D008969:Molecular Sequence Data; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000145:classification / Q000235:genetics*; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000145:classification / Q000235:genetics*; D016415:Sequence Alignment; D009626:Terminology as Topic
D016693:Receptors, Antigen, T-Cell, alpha-beta; D016692:Receptors, Antigen, T-Cell, gamma-delta