Surgical management of melanoma.
The incidence of melanoma is rising more rapidly than any other malignancy. More conservative margins of excision have been established and the role of elective node dissection awaits determination by prospective randomized trials. Lymphoscintigraphy has clarified lymphatic drainage from watershed areas. Lymphatic mapping and sentinel node biopsy may lead to acceptance of selective lymphadenectomy, and also allows for more sensitive staging. Further advances in outcome require the development of effective systemic adjuvant therapies. Until such time, surgery continues to play a pivotal role in all stages.
Whooley
B P
BP
Department of Surgery, St Vincent's Hospital & Medical Center of New York/New York Medical College, New York, 10011, USA.
Wallack
M K
MK
D001706:Biopsy; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008545:Melanoma / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D009367:Neoplasm Staging; D011379:Prognosis; D011877:Radionuclide Imaging; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*