Early detection of cutaneous microcirculatory change during hemorrhage using a laser Doppler flowmetry.
The purpose of the present study was to evaluate the usefulness of cutaneous microcirculatory monitoring during hemorrhage. We observed changes in cutaneous blood volume, velocity and flow of five adult rabbits during hemorrhage by using a laser Doppler flowmetry. Mean arterial blood pressure, heart rate and blood gas values were measured. Cutaneous blood volume, velocity and flow decreased significantly after drawing 10 mL/kg of blood, while heart rate, mean arterial blood pressure and blood gas did not change. The decrease of cutaneous blood velocity preceded that of blood volume and was associated more deeply with the reduction of blood flow. In conclusion, cutaneous microcirculatory monitoring using laser Doppler flowmetry is a sensitive technique for detecting early changes of circulatory failure caused by hemorrhage.
Takayanagi
T
T
Department of Pediatrics, Nagasaki University School of Medicine, Japan.
Fukuda
M
M
Tsuji
Y
Y
Nakazawa
M
M
D000818:Animals; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017078:Laser-Doppler Flowmetry; D008297:Male; D008833:Microcirculation / Q000000981:diagnostic imaging; D011817:Rabbits; D012867:Skin / Q000098:blood supply*; D014463:Ultrasonography