Recurrent recall of sunburn by methotrexate.
An unusual recall reaction of sunburn with methotrexate use has been previously reported. Heretofore, all reports have documented a single occurrence of this reaction in each patient. We report, for the first time, a patient who developed recurrent facial sunburn recalls while receiving methotrexate for psoriasis. This reaction is distinct from true photosensitivity. Photosensitivity is listed in the drug brochure for methotrexate. However, a review of the literature does not support true photosensitivity associated with methotrexate.
Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
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D000284:Administration, Oral; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005148:Facial Dermatoses / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy; D012008:Recurrence; D013471:Sunburn / Q000209:etiology*; D013472:Sunlight / Q000009:adverse effects
D003879:Dermatologic Agents; D008727:Methotrexate