Pneumococcal bacteremia in two tertiary care hospitals in Winnipeg, Canada. Pneumococcal Bacteremia Study Group.
OBJECTIVE
To review experience with pneumococcal bacteremia at two Canadian tertiary care centers.


METHODS
Retrospective record review.


METHODS
Two tertiary acute care teaching hospitals in Winnipeg, Manitoba.


METHODS
Patients identified with pneumococcal bacteremia during an 8-year period.


RESULTS
Hospital records were reviewed for 534 of 617 patients with pneumococcal bacteremia. The overall case fatality ratio was 70 (13%), varying from 3.2% in children to 43% in those older than 80 years. Twenty-seven (18%) hospitalized children and 68 (23%) adults required ICU admission. Duration of hospitalization was 14.9 +/- 24.9 and 11.0 +/- 19.1 days for children at the two institutions and 22.5 +/- 37.6 days and 38 +/- 93 days for adults. For the 217 viable pneumococcal strains studied, 89% were serotypes included in the present 23-valent vaccine. Documentation of prior vaccination was present for only 9 (1.7%) patients, although 281 (89%) adults and 99 (45%) children met criteria for vaccination.


CONCLUSIONS
Mortality in our population is similar to previous reports. More widespread pneumococcal vaccination in eligible populations may not only decrease mortality, but may also provide savings through decreased hospital admission and need for intensive care.
Department of Internal Medicine, Health Sciences Centre, Winnipeg, Manitoba, Canada.
Y
Y
Mirzanejad
S
S
Roman
J
J
Talbot
L
L
Nicolle
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology; D002423:Cause of Death; D002648:Child; D003422:Critical Care / Q000706:statistics & numerical data; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006769:Hospitals, General; D006784:Hospitals, Teaching; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008350:Manitoba / Q000453:epidemiology; D008875:Middle Aged; D010343:Patient Admission / Q000706:statistics & numerical data; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D012189:Retrospective Studies; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000276:immunology; D014611:Vaccination
D001428:Bacterial Vaccines