The mode of Roux-en-Y reconstruction affects motility in the efferent limb.
OBJECTIVE
To compare motility of a Roux-en-Y esophagojejunostomy after total gastrectomy with normal jejunal motility and to determine the effect on motility of the incorporation of a pouch in the reconstruction.


METHODS
Jejunal motility in normal subjects was compared with jejunal motility in the Roux-en-Y reconstruction with and without a Hunt-Lawrence pouch.


METHODS
The case were collected during a 4-year period at a university hospital. The mean time from resection to study was 14 months (range, 4 to 49 months).


METHODS
Seven control patients were compared with 10 patients with a Roux-en-Y reconstruction and 17 with a Roux-en-Y and Hunt-Lawrence pouch.


METHODS
The fasting-state motility of the jejunum used for reconstruction was measured by a water-perfused manometric system for 2 to 4 hours with the subject in the supine position.


RESULTS
Compared with normal subjects, patients with a Roux-en-Y esophagojejunostomy without a pouch had an increased number of phases of the interdigestive motor complex per hour (P < .05). The phases were of shorter duration with a random sequence and increased total time spent in the quiescent phase 1 (P < .05). In patients with a pouch, no differences were detected between the motility in the pouch and the efferent limb. Compared with those without a pouch, there were significantly fewer orthograde interdigestive motor complex phase 3 fronts and more total time spent in phase 1 (P < .05).


CONCLUSIONS
Construction of a gastric substitute from jejunum leads to substantial motility changes. The addition of a pouch decreases the overall activity, which may contribute to the storage function of the pouch.
Department of Surgery, University of Southern California School of Medicine, Los Angeles, USA.
H
H
Thomas
J
J
Heimbucher
K H
KH
Fuchs
S M
SM
Freys
T R
TR
DeMeester
J H
JH
Peters
C G
CG
Bremner
A
A
Thiede
D000328:Adult; D000713:Anastomosis, Roux-en-Y / Q000379:methods; D004946:Esophagostomy / Q000379:methods*; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D007582:Jejunostomy / Q000379:methods*; D007583:Jejunum / Q000502:physiology*; D008297:Male; D016896:Treatment Outcome