Cancer. Exploring the bowels of DNA methylation.
Recent studies of mice lacking methyltransferase, and of genes that modify cancer susceptibility, have shed light on the long-standing problem of how DNA methylation affects carcinogenesis.
Balmain
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Department of Medical Oncology, University of Glasgow, Bearsden, UK.
D000818:Animals; D004247:DNA / Q000378:metabolism*; D015254:DNA Modification Methylases / Q000378:metabolism; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008745:Methylation; D051379:Mice; D009369:Neoplasms / Q000235:genetics*; D011519:Proto-Oncogenes
D004247:DNA; D015254:DNA Modification Methylases