Langerhans' cell histiocytosis: possible association with malignant germ cell tumour.
A rare case of adult onset Langerhans' cell histiocytosis associated with dysgerminoma in a 35 year old Chinese woman is reported. The patient had a history of dysgerminoma of left ovary 15 years previously and had undergone surgery followed by radiotherapy and an uneventful recovery. She presented again in March 1994, this time with a left clavicular mass, which was shown histologically to be Langerhans' cell histiocytosis. The report illustrates the probable association between the two lesions, with some discussion on the underlying pathogenesis.
Ng
W K
WK
Department of Pathology, University of Hong Kong, Queen Mary Compound, Hong Kong.
Lam
K Y
KY
Ng
I O
IO
D000328:Adult; D004407:Dysgerminoma / Q000150:complications* / Q000473:pathology; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology