Structure of HIV-1 protease with KNI-272: a transition state mimetic inhibitor containing allophenylnorstatine.
Baldwin
E T
ET
NCI-Frederick Cancer Research and Development Center, PRI/DynCorp, Structural Biochemistry Program, Frederick, Maryland 21702, USA.
Bhat
T N
TN
Gulnik
S
S
Liu
B
B
Kiso
Y
Y
Mitsuya
H
H
Erickson
J W
JW
D000595:Amino Acid Sequence; D000998:Antiviral Agents / Q000737:chemistry*; D001665:Binding Sites; D016333:HIV Protease / Q000737:chemistry* / Q000378:metabolism*; D017320:HIV Protease Inhibitors / Q000737:chemistry*; D006801:Humans; D006860:Hydrogen Bonding; D007700:Kinetics; D008958:Models, Molecular; D009842:Oligopeptides / Q000737:chemistry*; D010654:Phenylbutyrates; D011487:Protein Conformation
D000998:Antiviral Agents; D017320:HIV Protease Inhibitors; D009842:Oligopeptides; D010654:Phenylbutyrates; C034940:3-amino-2-hydroxy-4-phenylbutanoic acid; D016333:HIV Protease; C077822:kynostatin 272