Inhibition of DNA adduct formation of 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) by dietary indole-3-carbinol (I3C) in the mammary gland, colon, and liver of the female F-344 rat.
Schut
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HA
Department of Pathology, Medical College of Ohio, Toledo 43614, USA.
Dashwood
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RH
D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D002273:Carcinogens / Q000378:metabolism* / Q000493:pharmacokinetics; D003106:Colon / Q000378:metabolism; D018736:DNA Adducts / Q000037:antagonists & inhibitors* / Q000302:isolation & purification / Q000378:metabolism; D005260:Female; D007093:Imidazoles / Q000378:metabolism* / Q000493:pharmacokinetics; D007211:Indoles / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism; D008321:Mammary Glands, Animal / Q000378:metabolism; D051381:Rats; D011916:Rats, Inbred F344; D014018:Tissue Distribution
D016588:Anticarcinogenic Agents; D002273:Carcinogens; D018736:DNA Adducts; D007093:Imidazoles; D007211:Indoles; C049584:2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; C016517:indole-3-carbinol