[7 cases of carcinoma of the distal choledochus].
Seven patients with carcinoma of the lower third of the extrahepatic bile duct over a twenty year period, were analyzed with emphasis to the presentation, laboratory, surgical findings, histology and outcome. There were four males and three females. The mean age was 59 years (range 53 to 68). All patients presented jaundice, abdominal pain and weight loss. Serum bilirubin levels were over 5 mg/dL in six patients (86%). The most useful diagnostic studies were endoscopic cholangiography, percutaneous cholangiography and computed tomography. All patients underwent a Whipple procedure. There was no operative mortality. In the long term follow-up, three patients were free of disease, and four had died. Tumor recurrence was high (43%) in spite of the curative resection.
Departmento de Cirugía, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
T J
TJ
Gómez-Méndez
J C
JC
Morales-Linares
C
C
Chan
L
L
Quintanilla
L
L
de la Garza
M F
MF
Herrera
D000230:Adenocarcinoma / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003138:Common Bile Duct Neoplasms / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D008937:Mitomycins / Q000008:administration & dosage; D016577:Pancreaticoduodenectomy; D012189:Retrospective Studies
D008937:Mitomycins; D004317:Doxorubicin; D005472:Fluorouracil
Siete casos de carcinoma del colédoco distal.