Neuropsychological features of progressive supranuclear palsy.
Progressive supranuclear palsy (PSP) is the epitome of a subcortical dementia process. Due to its relative rarity, there is only a small literature on the neuropsychological consequences of PSP. The findings to date demonstrate that PSP patients have dramatically slowed information processing and motor execution, rapid forgetting, problems in orienting attentional resources, and difficulty in planning and shifting conceptual sets. The pattern and severity of these deficits are unique to PSP and suggest that the study of PSP patients can provide a special insight into brain-behavior relations.
Cognitive Neuroscience Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA.
J
J
Grafman
I
I
Litvan
M
M
Stark
D001921:Brain / Q000503:physiopathology; D003072:Cognition Disorders / Q000209:etiology; D006801:Humans; D001523:Mental Disorders / Q000209:etiology; D012720:Severity of Illness Index; D013494:Supranuclear Palsy, Progressive / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology