Use of murine models of cytokine-secreting tumor vaccines to study feasibility and toxicity issues critical to designing clinical trials.
Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
E M
EM
Jaffee
A
A
Lazenby
J
J
Meurer
F
F
Marshall
K M
KM
Hauda
C
C
Counts
H
H
Hurwitz
J W
JW
Simons
H I
HI
Levitsky
D M
DM
Pardoll
D000818:Animals; D017321:Clinical Trials, Phase I as Topic; D004195:Disease Models, Animal; D005260:Female; D005615:Freezing; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000097:blood / Q000378:metabolism*; D016219:Immunotherapy, Adoptive / Q000009:adverse effects; D008546:Melanoma, Experimental / Q000378:metabolism* / Q000628:therapy*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D014407:Tumor Cells, Cultured
D016178:Granulocyte-Macrophage Colony-Stimulating Factor