The neuropathology of parkinsonism: an overview.
The neuropathology of parkinsonism is reviewed as it occurs in primary (idiopathic) and secondary extrapyramidal syndromes. Present understanding of the significance of Lewy bodies in Parkinson's disease, diffuse Lewy body disease, and Lewy body variant of Alzheimer's disease is emphasized. The neuropathology produced by a variety of secondary causes is also considered to demonstrate the diverse lesions that can result in parkinsonism.
Department of Pathology, UCLA School of Medicine, Harbor-UCLA Medical Center, Torrance 90509, USA.
M E
ME
Cornford
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L
Chang
B L
BL
Miller
D000544:Alzheimer Disease / Q000150:complications; D001921:Brain / Q000503:physiopathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D016631:Lewy Bodies / Q000648:ultrastructure; D008297:Male; D009410:Nerve Degeneration; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D012737:Sex Factors