Sebaceous epithelioma: a review of twenty-one cases.
BACKGROUND
Sebaceous epithelioma is a benign tumor that must be differentiated from basal cell carcinoma and other appendageal tumors.


OBJECTIVE
Histologic and clinical findings were reviewed in 21 patients with sebaceous epitheliomas.


METHODS
Twenty-one cases of sebaceous epithelioma collected during a 5-year period were reviewed.


RESULTS
The tumors appeared as yellow to flesh-colored papules, most often on the face and neck. They consisted of basaloid cells with foci of sebaceous differentiation. Cystic spaces formed by holocrine degeneration or simulating sebaceous duct lining were common findings. Patients with sebaceous epitheliomas were more likely than the general population to have an internal malignancy.


CONCLUSIONS
Patients with sebaceous epithelioma should be examined for an underlying malignancy.
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
A M
AM
Dinneen
D R
DR
Mehregan
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000175:diagnosis; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000473:pathology; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology*; D012626:Sebaceous Gland Neoplasms / Q000473:pathology*