Prenatal diagnosis of trisomy 9. Six cases and a review of the literature.
Six prenatally diagnosed cases of trisomy 9 are reported and 22 previously reported cases are reviewed; the difficulty of genetic counselling for such cases and the variation in the percentage of trisomic cells in different tissues, thus making accurate diagnosis of trisomy 9 difficult, are emphasized. In addition to karyotyping results, ultrasound findings are important in achieving diagnoses. Finally, a course of action when prenatal trisomy 9 is detected is proposed.
Centre de Diagnostic Prénatal, Maternité Pellegrin, CHU Bordeaux, France.
R
R
Saura
W
W
Traore
L
L
Taine
Z Q
ZQ
Wen
D
D
Roux
B
B
Maugey-Laulom
M
M
Ruffie
A
A
Vergnaud
J
J
Horovitz
D000328:Adult; D002899:Chromosomes, Human, Pair 9; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014314:Trisomy / Q000175:diagnosis*