[The fatty acid composition of the phospholipids of the erythrocyte membranes, thrombocytes and alpha-lipoproteins in schizophrenia patients].
19 patients with different forms of schizophrenia as well as 10 healthy individuals and 6 alcoholic patients as a controls were examined. In was found that the fatty acid composition of phospholipids from schizophrenic patients erythrocytes membranes and platelets was not differed from control groups except the continuous sluggish schizophrenic patients. The decrease of polyunsaturated fatty acids C 20:3 (w = 9) and the increase C 20:5 (w = 6) were observed in the last case. The decrease of linoleic acid and C 20:5 (w = 3) acids levels in phospholipids of alpha-lipoprotein fraction was observed in all patients independently of their nosological form. The author suggests that last finding is the possible cause of the fatty acids deficiency chronization in brain structures.
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Iusupova
D000437:Alcoholism / Q000097:blood; D001792:Blood Platelets / Q000737:chemistry*; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D004910:Erythrocyte Membrane / Q000737:chemistry*; D005231:Fatty Acids, Unsaturated / Q000097:blood*; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008563:Membrane Lipids / Q000097:blood*; D010743:Phospholipids / Q000097:blood*; D012559:Schizophrenia / Q000097:blood*
D005231:Fatty Acids, Unsaturated; D008075:Lipoproteins, HDL; D008563:Membrane Lipids; D010743:Phospholipids
Zhirnokislotnyĭ sostav fosfolipidov éritrotsitarnykh membran, trombotsitov i al'fa-lipoproteidov u bol'nykh shizofrenieĭ.