Epidemic spread of plasmid-mediated tetracycline resistant Neisseria gonorrhoeae in Zaire.
A cohort of 650 prostitutes from Kinshasa, Zaire, was followed at monthly intervals for sexually transmitted diseases as part of an HIV intervention project. Neisseria gonorrhoeae isolates, obtained during a period of 30 months, were auxotyped, serotyped and tested for antimicrobial susceptibility. Among 1085 gonococcal isolates tested, 725 (67%) produced beta-lactamase (PPNG) and 323 (30%) showed plasmid-mediated resistance to tetracyline (TRNG). Over time, the prevalence of PPNG varied between 60 and 73%, while the level of TRNG increased from 11 to 45%.
Division of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium.
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Van Dyck
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Laga
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Manoka
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Behets
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Piot
D015023:Democratic Republic of the Congo / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006069:Gonorrhea / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000145:classification*; D011159:Population Surveillance; D015995:Prevalence; D011815:R Factors; D012703:Serotyping; D011477:Sex Work; D013753:Tetracycline Resistance; D014504:Urban Health