[Do employees in the rubber industry have an increased risk of laryngeal cancer?].
Blue collar workers in the rubber industry are exposed to a number of toxic and potentially carcinogenic substances. In the last years an increased incidence of laryngeal cancer has been found in this group of workers. Besides naphthylamine, asbestos, vulcanization fumes and especially nitrosamines have been considered as possible causative agents. The present paper reviews the most relevant epidemiological studies on this topic published within the last 12 years and includes 17 cohort studies and 5 cases control studies. Only some of these papers indicate an increased risk for head and neck cancer due to employment in the rubber industry. Further in most studies the reported standard mortality ratios or relative risk ratios were not increased significantly. In nearly all of these studies an adjustment was not made for alcohol and tobacco consumption to compromise findings.
HNO-Abteilung, Bundeswehrkrankenhaus Ulm.
M
M
Tisch
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P
Münch
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H
Maier
D002273:Carcinogens / Q000009:adverse effects*; D016022:Case-Control Studies; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007822:Laryngeal Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D009784:Occupational Diseases / Q000139:chemically induced* / Q000453:epidemiology; D012307:Risk Factors; D012408:Rubber / Q000009:adverse effects*
D002273:Carcinogens; D012408:Rubber
Haben Arbeitnehmer in der Gummiindustrie ein erhöhtes Kehlkopfkrebsrisiko?