Therapy-resistant seizures in pseudohypoparathyroidism. A case report.
A 30 year-old, mentally retarded female presented with uncontrolled seizures. The diagnosis of pseudohypoparathyroidism was established on grounds of clinical, laboratory and radiological evaluation. Despite normalization of serum calcium levels with vitamin D treatment, the patient continued to suffer from frequent convulsions. The possible pathogenesis of the therapy-resistant seizures and the therapeutic approach are discussed.
Department of Neurology, Assaf Harofeh Medical Center, Zerifin, Israel.
L
L
Pollak
C
C
Klein
M
M
Tieder
A
A
Arlazoroff
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D002118:Calcium / Q000097:blood; D004351:Drug Resistance; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D011547:Pseudohypoparathyroidism / Q000150:complications*; D012640:Seizures / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed
D000927:Anticonvulsants; D002118:Calcium