Intestinal infarction due to nifedipine overdose.
The first case of intestinal infarction associated with nifedipine overdose is presented. This is also the first reported case of an overdose with an extended release nifedipine preparation. The formation of a large gastric concretion of nifedipine tablets may have enhanced its local vasodilatory effects thereby producing mesenteric hypoperfusion, ischemia, and infarction.
Department of Emergency Medicine, University of Rochester School of Medicine, NY 14642, USA.
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D000006:Abdomen, Acute / Q000175:diagnosis / Q000000981:diagnostic imaging; D000328:Adult; D002121:Calcium Channel Blockers / Q000506:poisoning; D017809:Fatal Outcome; D006801:Humans; D007238:Infarction / Q000139:chemically induced*; D007422:Intestines / Q000098:blood supply*; D007511:Ischemia / Q000139:chemically induced; D008297:Male; D009543:Nifedipine / Q000506:poisoning*; D011859:Radiography; D014665:Vasodilator Agents / Q000506:poisoning*
D002121:Calcium Channel Blockers; D014665:Vasodilator Agents; D009543:Nifedipine