Allogeneic BMT from a donor with fragile X syndrome: cytogenetic and molecular evaluation.
We report the first case of engraftment of bone marrow collected from a donor with Fragile X syndrome with subsequent cytogenetic and molecular evaluation. Engraftment was prompt and stable. Whilst the Fragile X abnormality could be detected initially by molecular techniques in the peripheral blood, it could not be detected cytogenetically while the patient was receiving CsA.
Morton
J
J
Department of Haematology and Bone Marrow Transplantation, Royal Brisbane Hospital, Herston, Queensland, Australia.
Arnold
L
L
Fletcher
B
B
McCarthy
C
C
Rowell
J
J
Durrant
S
S
D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics*; D006801:Humans; D008297:Male; D014019:Tissue Donors; D014184:Transplantation, Homologous; D014960:X Chromosome