Computer simulation and analysis of the reaction pathway for the decomposition of the hydrated peptide bond in aspartic proteases.
Cachau
R E
RE
Structural Biochemistry Program, PRI/DynCorp, National Cancer Institute, Frederick Cancer Research and Development Center, MD 21702-1210, USA.
Topol
I A
IA
Burt
S K
SK
Silva
A M
AM
Erickson
J W
JW
D001224:Aspartic Acid; D016282:Aspartic Acid Endopeptidases / Q000737:chemistry* / Q000378:metabolism*; D003198:Computer Simulation; D016333:HIV Protease / Q000737:chemistry* / Q000378:metabolism; D015497:HIV-1 / Q000201:enzymology; D006801:Humans; D008961:Models, Structural; D011487:Protein Conformation
D001224:Aspartic Acid; D016282:Aspartic Acid Endopeptidases; D016333:HIV Protease