Tolerance of chronically-diseased liver to prolonged hemihepatic ischemia during hepatectomy.
Seventeen patients with chronic liver disease underwent prolonged warm ischemia of hemi-lobe during liver resection. Those included 15 cirrhotic patients and two with chronic hepatitis. The hemi-hepatic ischemia was carried out with a liver clamp. The normothermic liver ischemia time of 40 to 70 minutes (53.8 +/- 10.4 minutes, mean +/- SD) were tolerated well with an acceptable postoperative course and no mortality. The liver with cirrhosis or chronic hepatitis can tolerate a hemi-hepatic ischemia of up to 70 minutes for patients with no high-risk factors.
Department of Surgery I Oita Medical University, Japan.
Y I
YI
Kim
T
T
Ishii
S
S
Kitano
A
A
Morimoto
K
K
Nakashima
N
N
Kamada
K
K
Sugimachi
D000368:Aged; D005260:Female; D006498:Hepatectomy / Q000379:methods*; D006509:Hepatitis B / Q000503:physiopathology / Q000601:surgery*; D006526:Hepatitis C / Q000503:physiopathology / Q000601:surgery*; D006521:Hepatitis, Chronic / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007511:Ischemia / Q000503:physiopathology*; D008099:Liver / Q000098:blood supply*; D008103:Liver Cirrhosis / Q000503:physiopathology / Q000601:surgery*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology*; D016896:Treatment Outcome