Application of two STRs (VWA and TPO) to human population profiling: survey in Galicia.
We have studied two tetranucleotide short tandem repeats (STRs) (VWA and human TPO) in 260 individuals from Galicia by means of polymerase chain reaction amplification followed by electrophoresis separation and silver staining. The feasibility of the analytical technique and the level of polymorphism attained by both systems (PIC = 0.764 for VWA; PIC = 0.563 for TPO) allow us to consider the two STRs as suitable and informative markers in routine population profiling studies.
Luis
J R
JR
Departamento de Antropoloxía, Facultade de Bioloxía, Universidade de Santiago, Galicia, Spain.
Caeiro
B
B
D004247:DNA / Q000235:genetics*; D004586:Electrophoresis; D005828:Genetics, Population; D006801:Humans; D007453:Iodide Peroxidase / Q000032:analysis / Q000235:genetics; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics; D013030:Spain; D014841:von Willebrand Factor / Q000032:analysis / Q000235:genetics
D014841:von Willebrand Factor; D004247:DNA; D007453:Iodide Peroxidase