Reversible ophthalmoplegia in CPEO.
OBJECTIVE
To present a case of improvement of ocular motility in a patient with chronic progressive external ophthalmoplegia (CPEO) with Coenzyme Q10.


METHODS
Coenzyme Q10 300 mg daily was given for three years with a three-day trial period of 200 mg daily after one year. Ocular ductions were measured by synoptophore.


RESULTS
Ocular ductions improved with treatment with Coenzyme Q10.


CONCLUSIONS
Coenzyme Q10, is effective in limiting the severity of ophthalmoplegia in this case.
Dunlop
I S
IS
Sydney Eye Hospital, Woolloomooloo, NSW.
Dunlop
P
P
D000328:Adult; D002908:Chronic Disease; D003067:Coenzymes; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005133:Eye Movements; D005260:Female; D006801:Humans; D007625:Kearns-Sayre Syndrome / Q000150:complications; D009886:Ophthalmoplegia / Q000150:complications / Q000188:drug therapy*; D014451:Ubiquinone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D003067:Coenzymes; D014451:Ubiquinone; C024989:coenzyme Q10