Comparison of nylon and polypropylene sutures in a microvenous thrombosis model.
Thrombosis rates of femoral end-to-end microvenous anastomoses with nylon and polypropylene sutures (9-0 suture, 70 mu needle) were compared in a microvenous thrombosis model. The vessel injuries were produced during anastomosis by using a suture with a knot 1 cm from the needle. Anastomotic thrombosis rates were assessed by visual inspection and strip test at 24 hr postoperatively. Low thrombosis rates (0% and 20%, respectively) of anastomoses with both unknotted nylon and unknotted polypropylene sutures were obtained. Anastomoses with knotted nylon and polypropylene sutures resulted in 65% and 45% thrombosis rates, respectively. Statistical analyses showed that there were no significant differences between thrombosis rates, both in anastomosis performance with unknotted nylon and polypropylene sutures (P > 0.05) and with knotted nylon and polypropylene sutures (P > 0.05), while there were significant differences between the thrombosis rate using unknotted sutures and knotted sutures (P < 0.01). It was concluded that vascular injury, not suture material, is the main factor leading to thrombosis in this model.
Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, CA 94305, USA.
T E
TE
Ustüner
F
F
Zhang
W C
WC
Lineaweaver
D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D005268:Femoral Vein / Q000293:injuries / Q000473:pathology; D006083:Graft Occlusion, Vascular / Q000209:etiology*; D008297:Male; D009757:Nylons; D011126:Polypropylenes; D051381:Rats; D017207:Rats, Sprague-Dawley; D013536:Suture Techniques; D013537:Sutures; D013927:Thrombosis / Q000209:etiology*; D013997:Time Factors
D009757:Nylons; D011126:Polypropylenes