MRI evaluation of dexamethasone acetate therapy for osteoarthritis in the hand.
A patient with clinically diagnosed Stage I primary idiopathic osteoarthritis of the first metacarpal trapezium joint of the left hand received intra-articular administration of dexamethasone acetate. Compared to pretreatment T2- weighted MR images, greatly decreased MR signal intensity was observed in the affected joint space and adjacent soft tissues 2 days after dexamethasone acetate therapy. This was representative of reduced edema in the metacarpal trapezium joint and demonstrated the ability of MRI to follow pharmacological treatment for arthritis.
Tankhiwale
A
A
Department of Radiology, New York Methodist Hospital, Brooklyn 11215, USA.
Vullo
T
T
Markisz
J A
JA
Cahill
P T
PT
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003907:Dexamethasone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008662:Metacarpophalangeal Joint / Q000473:pathology*; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy* / Q000473:pathology*
D000893:Anti-Inflammatory Agents; D003907:Dexamethasone; C018038:dexamethasone acetate