Serum lipid profile in children of coronary heart disease patients.
Serum lipid and lipoprotein cholesterol levels were analysed in 44 children from 5-14 years of age (index), belonging to 29 parents diagnosed as coronary artery disease (CAD). 314 children of parents without any CAD served as control. Index group had significantly (P < .05) higher levels of total cholesterol (Tch), triglycerides (TG) and very low density lipo-proteins cholesterol (VLDLc) and low levels of high density lipoprotein cholesterol (HDLc) (P < .05). Index group revealed higher levels of cholesterol, triglycerides and low density lipoprotein cholesterol in 31.8%, 6.8% and 36% cases respectively. HDLc did not show any significant variation. Index group whose parents had hypercholesteremia (Tch > 260 mg/dl) with CAD had raised levels of Tch, TG, LDLs and VLDLc when compared with control group (P < .05).
Department of Pediatrics, Government Medical College, Srinagar.
W
W
Ali
A
A
Bandh
M
M
Ul Hassan
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000235:genetics; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000235:genetics; D006951:Hyperlipoproteinemias / Q000097:blood / Q000235:genetics; D015228:Hypertriglyceridemia / Q000097:blood / Q000235:genetics; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood
D008076:Cholesterol, HDL; D015243:Cholesterol, VLDL; D008055:Lipids; D008074:Lipoproteins; D002784:Cholesterol