Granulocytic sarcoma in patients with chronic myeloid leukaemia.
Granulocytic sarcoma is an unusual variant of myeloid malignancy most commonly encountered in the course of chronic or acute myeloid leukaemia. Of 60 patients of chronic myeloid leukaemia studied over 21 months, we encountered 6 (10%) cases of granulocytic sarcoma. Four of these had granulocytic sarcoma on their first presentation. All those who were receiving hydroxyurea did not fare well but one who was put on DAT (daunorubicin, cyftosine arabinocide, 6 thioguanine)regimen went into remission with complete disappearance of lesions.
Department of Haematology, Rawalpindi.
S
S
Ahmed
M
M
Anwar
S A
SA
Siddiqui
M
M
Saleem
P A
PA
Ahmad
S
S
Mushtaq
D000293:Adolescent; D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003630:Daunorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy / Q000473:pathology*; D017254:Leukemic Infiltration; D008297:Male; D008875:Middle Aged; D011379:Prognosis
D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D006918:Hydroxyurea; D003630:Daunorubicin