Bronchial carcinoid associated with Cushing's syndrome.
Bronchial carcinoid is the most frequent cause of Cushing's syndrome due to ectopic ACTH production. The authors report a case of bronchial carcinoid which diagnosis was difficult because of the presence of pulmonary mycosis, that determined a hypercorticosuprarenalism. Medical treatment with octreotide, ketoconazolo and mitotane was useless, and bilateral suprarenalectomy was performed. A scintigraphy with raced somatostatin revealed a left lung area capting radiation. A CT scan of the thorax revealed a lesion of the lingula and the patient underwent an atypical lung resection with complete solution of the symptom. The problems of diagnosis and treatment of neuroendocrine tumors of the lung are discussed and the importance of SSA in the diagnostic procedure is pointed out.
Oliaro
A
A
Department of Thoracic Surgery, University of Turin, Italy.
Filosso
P L
PL
Casadio
C
C
Ruffini
E
E
Mazza
E
E
Molinatti
M
M
Cianci
R
R
Porrello
C
C
Rastelli
M
M
Oliveri
F
F
D000182:ACTH Syndrome, Ectopic; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000328:Adult; D001984:Bronchial Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D002276:Carcinoid Tumor / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D003480:Cushing Syndrome / Q000175:diagnosis / Q000209:etiology*; D006729:Hormones, Ectopic / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D008172:Lung Diseases, Fungal / Q000150:complications / Q000175:diagnosis; D008297:Male
D006729:Hormones, Ectopic; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone