Con: glucose priming solutions should not be used for cardiopulmonary bypass.
In conclusion, the advantage of glucose-containing CPB priming solutions are quite modest. In contrast, the weight of current evidence strongly supports the notion that hyperglycemia is far more likely to be detrimental than beneficial to a brain challenged by ischemia, especially when there is reperfusion (hypotension or circulatory arrest) or when the brain is normothermic. Because neurologic complications pose such a serious threat to cardiac surgery patients, avoidance of hyperglycemia during surgery and CPB seems prudent at this time. Hence, CPB priming solutions should not contain glucose.
Department of Anesthesia, College of Medicine, University of Iowa, Iowa City 52245, USA.
B
B
Hindman
D002315:Cardiopulmonary Bypass / Q000379:methods*; D000075202:Contraindications; D005947:Glucose; D006801:Humans; D012307:Risk Factors; D012996:Solutions
D012996:Solutions; D005947:Glucose