How blood pressure in patients with non-insulin-dependent diabetes mellitus is influenced by stress.
The effects of reducing stress on blood pressure were investigated in 20 patients with non-insulin-dependent diabetes mellitus. An anxiolytic, fludiazepam, was administered to the patients for 12 weeks and their blood pressures and State Trait Anxiety Inventory scores at the beginning and end of treatment were compared. Systolic and diastolic blood pressures and trait and state anxiety scores were all significantly reduced during the treatment period. There was also a weak correlation between the extent of the improvement in the same anxiety score and the improvement in diastolic blood pressures.
Okada
S
S
Third Department of Internal Medicine, Okayama University Medical School, Japan.
Ichiki
K
K
Tanokuchi
S
S
Ishii
K
K
Hamada
H
H
Ota
Z
Z
D000328:Adult; D000368:Aged; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001007:Anxiety; D001569:Benzodiazepines; D001794:Blood Pressure / Q000187:drug effects; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology* / Q000523:psychology*; D003971:Diastole; D003975:Diazepam / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D013315:Stress, Psychological / Q000188:drug therapy; D013599:Systole
D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D003975:Diazepam; D006442:Glycated Hemoglobin; C006107:fludiazepam