Nuclear ultrastructures associated with the RNA synthesis and processing.
Relatively little is known about the spatial organization of RNA synthesis, processing, and transport in (mammalian) cell nuclei. This review summarizes results of electron microscopic mapping of RNA synthetic sites and macromolecules involved directly, or indirectly, in the metabolism of RNAs in somatic cell mammalian nuclei. Significance of these results will be discussed in the context of the molecular mechanisms underlying spatial arrangements of RNA metabolism.
Raska
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Laboratory of Cell Biology, Academy of Sciences of Czech Republic, Prague, Czech Republic.
D002466:Cell Nucleolus / Q000648:ultrastructure; D002467:Cell Nucleus / Q000378:metabolism / Q000648:ultrastructure*; D002843:Chromatin / Q000378:metabolism; D006801:Humans; D008854:Microscopy, Electron; D012313:RNA / Q000096:biosynthesis* / Q000378:metabolism; D012323:RNA Processing, Post-Transcriptional
D002843:Chromatin; D012313:RNA