Glutathion S-transferase activity and DDT-susceptibility of Malaysian mosquitos.
Comparative DDT-susceptibility status and glutathion s-transferase (GST) activity of Malaysian Anopheles maculatus, Culex quinquefasciatus and Aedes aegypti was investigated to ascertain the role of this enzyme in DDT resistance. The standardised WHO dose-mortality bioassay tests were used to determine DDT susceptibility in these mosquitos, whilst GST microassay (Brogdon and Barber, 1990) was conducted to measure the activity of this enzyme in mosquito homogenate. It appeared that DDT susceptibility status of Malaysian mosquitos was not correlated with GST activity.
Lee
H L
HL
Division of Medical Entomolgy, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia.
Chong
W L
WL
D000818:Animals; D009033:Culicidae / Q000187:drug effects / Q000201:enzymology*; D003634:DDT / Q000494:pharmacology*; D005982:Glutathione Transferase / Q000378:metabolism*; D007305:Insecticide Resistance / Q000502:physiology*; D007306:Insecticides / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D008296:Malaysia
D007306:Insecticides; D003634:DDT; D005982:Glutathione Transferase