[Turbo-spin-echo sequences with selective fat suppression (SPIR) in the MRI of focal liver lesions at 0.5 tesla].
OBJECTIVE
The value of T2 weighted turbo-spin-echo sequences with selective fat suppression (TSE-SPIR) in the detection and differential diagnosis of focal liver lesions was compared to TSE sequences and conventional T1 weighted spin-echo (T1 SE) sequences at 0.5T.


METHODS
In 50 patients with focal liver lesions T1 SE-TSE-, and TSE-SPIR sequences were performed. Two independent readers evaluated the sequences with regard to the image quality, fat suppression, and the number and conspicuity of liver lesions. Quantitative analysis was performed by tumour-liver contrast-to-noise (CNR) measurements.


RESULTS
From a total of 118 liver lesions the T1 SE sequence, the TSE sequence, and the TSE-SPIR sequence showed 85.6%, 83.9%, and 91.5%, respectively (p < 0.05). The tumour-liver CNR of malignant liver lesions was 30.2-46.6% higher on the TSE-SPIR sequence compared to the TSE sequence (p < 0.01). With the exception of fat-containing lesions there was no significant difference of CNR in benign lesions on both TSE sequences.


CONCLUSIONS
With regard to lesion detection the TSE-SPIR sequence is superior to the TSE sequence without fat suppression, whereas it is inferior to the TSE sequence in the differential diagnosis of benign and malignant lesions.
Radiologische Klinik, Universität Bonn.
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Kreft
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Kuhl
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Sommer
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Gieseke
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Schild
D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D016477:Artifacts; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D018709:Statistics, Nonparametric
Turbo-Spin-Echo-Sequenzen mit selektiver Fettunterdrückung (SPIR) in der MRT von fokalen Leberläsionen bei 0.5 Tesla.