Desmoplastic trichoepithelioma of the upper lip. A case report with histochemical features and observations on its histogenesis.
A case of desmoplastic trichoepithelioma of the upper lip investigated by histochemistry and immunocytochemistry is presented. There was histologic suggestion of cytoplasmic vacuolation that does not appear to have been previously described. Histochemical examination indicated the presence of glycogen within tumor cells and a reparative-type stroma. Immunocytochemical examination revealed variable reactivity for high molecular weight cytokeratin and colonization by Langerhans' cells. The observations suggest a follicular and sudoriferous differentiation for desmoplastic trichoepithelioma and hence an origin from a pluripotential adnexal keratinocyte.
Academic Unit of Oral Diseases, University of Liverpool School of Dentistry, UK.
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A
Triantafyllou
J
J
Scott
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A
Blacklock
D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008048:Lip Neoplasms / Q000737:chemistry / Q000473:pathology*; D008875:Middle Aged; D018295:Neoplasms, Basal Cell / Q000737:chemistry / Q000473:pathology*
D007633:Keratins