[Adrenal histoplasmosis in a non-insulin-dependent diabetic patient].
Adrenal histoplasmosis is a rare infection that can be misdiagnosed as tuberculosis. We present here a case of adrenal histoplasmosis in a 65 year-old male diabetic with marked weight loss. Laboratory investigations noticed an inflammatory syndrome and the abdominal computed tomography scanner reported an heterogenous left adrenal mass of 6 cm in diameter. Hormonal as well as bacteriological studies were negative. The patient was operated and the histopathological examination proved that the mass was a tuberculoma and an anti-tuberculous treatment was started. Four months later, the patient suffered from recurrence of symptoms and laboratory investigations confirmed the inflammatory syndrome and the abdominal computed tomography scanner showed a right adrenal mass. A surgical biopsy was performed and specific fungal researches proved that the lesion was due to Histoplasma capsulatum. The patient experienced a remarkable improvement under anti-fungal treatment.
Sert
C
C
Service d'endocrinologie-métabolisme, CHU Pitié-Salpétrière, Paris, France.
Achrafi
H
H
Jacqueminet
S
S
Hoang
C
C
Bosquet
F
F
Affres
H
H
Chigot
J P
JP
Thervet
F
F
D000307:Adrenal Gland Diseases / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D006660:Histoplasmosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male
D000935:Antifungal Agents
Histoplasmose surrénalienne chez un sujet idabétique non insulinodépendant.