MRI evaluation of dexamethasone acetate therapy for osteoarthritis in the hand.
A patient with clinically diagnosed Stage I primary idiopathic osteoarthritis of the first metacarpal trapezium joint of the left hand received intra-articular administration of dexamethasone acetate. Compared to pretreatment T2- weighted MR images, greatly decreased MR signal intensity was observed in the affected joint space and adjacent soft tissues 2 days after dexamethasone acetate therapy. This was representative of reduced edema in the metacarpal trapezium joint and demonstrated the ability of MRI to follow pharmacological treatment for arthritis.
Department of Radiology, New York Methodist Hospital, Brooklyn 11215, USA.
A
A
Tankhiwale
T
T
Vullo
J A
JA
Markisz
P T
PT
Cahill
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003907:Dexamethasone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008662:Metacarpophalangeal Joint / Q000473:pathology*; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy* / Q000473:pathology*
D000893:Anti-Inflammatory Agents; D003907:Dexamethasone; C018038:dexamethasone acetate