Characterization of antimicrobial resistance in enterococci of animal origin.
Among 97 enterococci cultured from animals, gentamicin MICs were > or = 2,000 micrograms/ml for 9 isolates and between 250 and 1,024 micrograms/ml for 6 isolates. For two isolates tested (gentamicin MICs, 256 and 512 micrograms/ml, respectively), there was no in vitro synergy with penicillin plus gentamicin, resistance was transferable, and there was no hybridization with a probe specific for 6'-aminoglycoside acetyltransferase-2"-aminoglycoside phosphotransferase. The results of the study indicate the presence of a unique gentamicin resistance genotype in enterococci of animal origin.
Thal
L A
LA
Department of Medicine, William Beaumont Hospital, Royal Oak, Michigan 48073, USA.
Chow
J W
JW
Mahayni
R
R
Bonilla
H
H
Perri
M B
MB
Donabedian
S A
SA
Silverman
J
J
Taber
S
S
Zervos
M J
MJ
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001717:Birds; D002417:Cattle; D002645:Chickens; D004352:Drug Resistance, Microbial; D016983:Enterococcus / Q000187:drug effects*; D005516:Food Microbiology; D005839:Gentamicins / Q000494:pharmacology; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology* / Q000662:veterinary*; D006736:Horses; D008826:Microbial Sensitivity Tests; D013552:Swine
D000900:Anti-Bacterial Agents; D005839:Gentamicins