Reconstruction of suboccipital craniectomy defects with hydroxyapatite cement: a preliminary report.
Hydroxyapatite cement, a new biomaterial presently under clinical investigation, has been demonstrated to have potentially wide application in cranial reconstruction. We describe our experience with this biologic bone cement in the reconstruction of suboccipital craniectomy defects in seven patients after vestibular schwannoma removal. With up to 2-year follow-up, cranial bone integrity has been reestablished in five patients. Dissolution of cement has occurred in dependent areas and appears to be technique related. Cranial bone contour appears dependent on the amount of cement used. The frequency of debilitating postoperative headache was reduced in these patients when compared to patients who had no reconstruction of the craniectomy defect. Reconstruction of the bony defect after suboccipital craniectomy with hydroxyapatite cement is not only useful to restore cranial contour, but also appears to reduce some of the functional deficits attributed to this surgical approach.
Department of Surgery, Yale University School of Medicine, New Haven, Conn 06520, USA.
J F
JF
Kveton
C D
CD
Friedman
J M
JM
Piepmeier
P D
PD
Costantino
D001672:Biocompatible Materials; D001843:Bone Cements / Q000009:adverse effects; D005500:Follow-Up Studies; D006261:Headache / Q000139:chemically induced; D006801:Humans; D006882:Hydroxyapatites / Q000009:adverse effects; D011183:Postoperative Complications; D012886:Skull / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D001672:Biocompatible Materials; D001843:Bone Cements; D006882:Hydroxyapatites