[Castleman's disease: evaluation of 338 cases].
OBJECTIVE
To evaluate a large group of patients with Castleman's tumours (Castleman's disease = MC) with regard to age, sex and tumour localisation.


METHODS
338 cases of MC were evaluated. All cases were registered by the Lymphknotenregister of the German Society of Pathology, Kiel.


RESULTS
292 MC of the hyaline vascular type (MC-HV) and 46 of the plasma cell type (MC-PC) were found, 259 (76.6%) in nodal and 79 (23.4%) in extranodal localisation. Main nodal localisation were the neck (25.5%) and the axilla (12.8%). The mediastinum was involved in only 6.2%. There was a slight preference of female (56%) compared to male (44%). Patients with MC-PC (mean age: 50 +/- 16.9 years) were significantly older (p < 0.001) than patients with MC-HV (mean age: 39 +/- 18.9 years).


CONCLUSIONS
The main localisation of MC is the neck. MC-HV is more common than MC-PC. There is a slight preference for women. Mean age of patients with MC-PC is approximate 10 years higher than for MC-HV.
Klinik für Radiologische Diagnostik, Christian-Albrechts-Universität zu Kiel.
H
H
Schwarzenberg
H H
HH
Wacker
R J
RJ
Elfeldt
G
G
Brinkmann
M
M
Heller
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005871:Castleman Disease / Q000175:diagnosis / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D012737:Sex Factors; D014057:Tomography, X-Ray Computed
Morbus Castleman: Auswertung von 338 Fällen.