Fludarabine phosphate and 2-chlorodeoxyadenosine: immunosuppressive DNA synthesis inhibitors with potential application in islet allo- and xenotransplantation.
Goodman
E R
ER
Department of Surgery, Columbia University, New York, N.Y. 10032, USA.
Fiedor
P S
PS
Fein
S
S
Sung
R S
RS
Athan
E
E
Hardy
M A
MA
D000818:Animals; D017338:Cladribine / Q000494:pharmacology*; D004247:DNA / Q000096:biosynthesis; D003921:Diabetes Mellitus, Experimental / Q000601:surgery; D006085:Graft Survival / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D016381:Islets of Langerhans Transplantation / Q000276:immunology*; D008213:Lymphocyte Activation / Q000187:drug effects; D007959:Lymphocyte Culture Test, Mixed; D008212:Lymphocyte Depletion; D051381:Rats; D011917:Rats, Inbred Lew; D011920:Rats, Inbred WF; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous; D001084:Vidarabine Phosphate / Q000031:analogs & derivatives* / Q000494:pharmacology
D007166:Immunosuppressive Agents; D001084:Vidarabine Phosphate; C042382:fludarabine phosphate; D017338:Cladribine; D004247:DNA