Treatment of fluorosed and white-spot human enamel with calcium sucrose phosphate in vitro.
A number of treatments have been devised to improve the appearance of fluorosed enamel. However, many of these have been empirically based, and the success of the various treatment regimens have not been quantitated. In this study, the relative whiteness of normal, mildly fluorosed, moderately fluorosed, and carious white-spot lesions on extracted teeth was quantitated by light reflectance using a Minolta Chroma Meter. The color was again determined following a number of treatment regimens to assess the potential use of various agents in treating the enamel lesions. Treatment of the enamel with a 35% hydrogen peroxide gel resulted in a significantly increased whitening, which was not reduced by subsequent treatment (P < 0.05). Removal of the enamel surface with a dental bur, followed by treatment with 5.25% sodium hypochlorite and placement in an artificial saliva was successful for returning white-spot lesions to a normal enamel color. Treatment of enamel with 5.25% sodium hypochlorite followed by calcium sucrose phosphate paste and placement in artificial saliva was most successful in returning both white-spot and fluorosed lesions to a normal color. SEM imaging of the calcium sucrose phosphate treated enamel suggests that this treatment filled the porous enamel, resulting in a normal light reflectance from the enamel.
Den Besten
P
P
University of California, San Francisco, USA.
Giambro
N
N
D002130:Calcium Phosphates / Q000627:therapeutic use*; D003743:Dental Enamel / Q000648:ultrastructure; D003745:Dental Enamel Permeability; D009050:Fluorosis, Dental / Q000188:drug therapy*; D006801:Humans; D006861:Hydrogen Peroxide / Q000627:therapeutic use; D066298:In Vitro Techniques; D008027:Light; D008855:Microscopy, Electron, Scanning; D016062:Porosity; D012973:Sodium Hypochlorite / Q000627:therapeutic use; D013395:Sucrose / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014073:Tooth Bleaching / Q000379:methods*; D017001:Tooth Demineralization / Q000188:drug therapy
D002130:Calcium Phosphates; C006875:calcium sucrose phosphate; D013395:Sucrose; D006861:Hydrogen Peroxide; D012973:Sodium Hypochlorite