[Morphological features of tissue reactions in combined treatment of experimental tuberculosis induced by xenobiotics].
The trend to aggravated running and contribution of air pollution of large industrial centers with polycyclic aromatic hydrocarbons (PAH) to tuberculosis onset and progress dictate the necessity of the search for new treatment methods. The authors made an attempt to treat experimental tuberculosis with sodium glutamate and isoniazide under chronic exposure to PAH dust. Sodium glutamate especially in combination with isoniazide produces a good effect enhancing granulomatous reactions fibroplastic processes in the foci of specific inflammation. Sodium glutamate is thought an effective pathogenetic treatment of tuberculosis.
Pavlov
V A
VA
Kazak
T I
TI
Kleĭn
A V
AV
Nosova
N A
NA
D000818:Animals; D004359:Drug Therapy, Combination; D006168:Guinea Pigs; D007538:Isoniazid / Q000008:administration & dosage*; D011083:Polycyclic Compounds / Q000009:adverse effects*; D012970:Sodium Glutamate / Q000008:administration & dosage*; D014376:Tuberculosis / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology*; D014386:Tuberculosis, Hepatic / Q000139:chemically induced / Q000188:drug therapy / Q000473:pathology; D014388:Tuberculosis, Lymph Node / Q000139:chemically induced / Q000188:drug therapy / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000139:chemically induced / Q000188:drug therapy / Q000473:pathology; D015262:Xenobiotics / Q000009:adverse effects*
D011083:Polycyclic Compounds; D015262:Xenobiotics; D007538:Isoniazid; D012970:Sodium Glutamate
Morfologicheskie osobennosti tkanevykh reaktsiĭ pri kompleksnoĭ terapii éksperimental'nogo tuberkuleza, razvivshegosia na fone predvaritel'nogo vozdeĭstviia ksenobiotikov.