Noninfectious inflammatory response to gold weight eyelid implants.
We describe three patients with noninfectious inflammatory reactions to gold weight eyelid implants, a complication not previously reported. Eyelid edema and erythema developed gradually in each patient, and maximal inflammation that prompted treatment was present at 12, 3, and 5 weeks, respectively, after surgery in the three patients. Management involved removal of the implant in the first patient, oral corticosteroids followed by replacement of the implant by a platinum weight in the second patient, and a local corticosteroid injection with retention of the implant in the third. Histopathological features included a thick eosinophilic coagulum at the tissue-gold interface and an intense, predominantly lymphocytic infiltrate in the collagenous capsule that surrounded the implants. Gold weight eyelid implants can elicit a gradually progressive inflammatory response. In at least some cases, local corticosteroid injection may suppress the inflammation and permit retention of the implant.
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee 53226, USA.
R L
RL
Bair
G J
GJ
Harris
D B
DB
Lyon
R A
RA
Komorowski
D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001762:Blepharitis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D004487:Edema / Q000209:etiology / Q000473:pathology / Q000628:therapy; D004890:Erythema / Q000209:etiology / Q000473:pathology / Q000628:therapy; D005141:Eyelid Diseases / Q000209:etiology / Q000473:pathology / Q000628:therapy; D005143:Eyelids / Q000601:surgery; D005158:Facial Paralysis / Q000150:complications; D005260:Female; D006046:Gold / Q000009:adverse effects*; D006801:Humans; D007634:Keratitis / Q000209:etiology / Q000517:prevention & control; D008875:Middle Aged; D019736:Prostheses and Implants / Q000009:adverse effects*; D012086:Reoperation; D013256:Steroids
D000893:Anti-Inflammatory Agents; D013256:Steroids; D006046:Gold