Microdontia with severe microcephaly and short stature in two brothers: osteodysplastic primordial dwarfism with dental findings.
Two brothers from a black family had microcephaly, short stature, and generalized microdontia. Endocrine and chromosome studies were normal, and mild skeletal manifestations were present. The patients may represent a distinct dental-skeletal dysplasia, possibly osteodysplastic primordial dwarfism type II. Attention to dental manifestations in similar cases may be useful for classification.
Department of Pediatrics, Harbor-UCLA Medical Center, Torrance 90502, USA.
H J
HJ
Lin
G Y
GY
Sue
C D
CD
Berkowitz
J A
JA
Brasel
R S
RS
Lachman
D000293:Adolescent; D002648:Child; D004392:Dwarfism / Q000145:classification / Q000235:genetics*; D006801:Humans; D008297:Male; D008831:Microcephaly / Q000235:genetics*; D014071:Tooth Abnormalities / Q000235:genetics*