[Study on Alpiniae Fructus. I. Pharmacological evidence of efficacy of Alpiniae Fructus on ancient herbal literature].
Pharmacological effects on anti-diuresis, anti-ulceration, anti-dementia and learning function of 50% ethanolic extract (AO-ext) from Alpiniae Fructus (fruit of Alpinia oxyphylla) removed seed vessel were investigated in order to prove the evidence of the efficacy of Alpiniae Fructus on the ancient herbal literature. AO-ext showed the effects of anti-diuresis, anti-ulceration, anti-dementia and on increase in the learning function in animals. And also, AO-ext exhibited the increasing effect on the serum 11-hydroxycorticosteroid (11-OHCS) level in the above-described experimental animals and in intact and hypophysectomized rats.
Faculty of Pharmaceutical Sciences, Kinki University, Osaka, Japan.
M
M
Kubo
H
H
Matsuda
T
T
Suo
J
J
Yamanaka
M
M
Sakanaka
M
M
Yoshimura
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000818:Animals; D003704:Dementia / Q000517:prevention & control; D004231:Diuresis / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005849:Gerbillinae; D007858:Learning / Q000187:drug effects; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014456:Ulcer / Q000517:prevention & control
D015062:11-Hydroxycorticosteroids; D004365:Drugs, Chinese Herbal