Three groups of afferent pulpal feline nerve fibres show different electrophysiological response properties.
Responses were recorded, after the application of four types of stimuli (slow or rapid elevation of temperature, hydrostatic negative pressure through thin dentine, and bradykinin directly applied to exposed pulp), from functional single fibres innervating the cat lower canine tooth pulp, dissected from the inferior alveolar nerve. A total of 278 single pulpal fibres were isolated. A fibres (n = 220) were divided into two groups: one (FA; fast A fibre, n = 160) consisting of those whose conduction velocities (CVs) were more than 2 m/s both inside and outside the tooth pulp, and the other (SA delta; slow A delta fibre, n = 60) consisting of those whose intrapulpal CVs were less than 2 m/s and extrapulpal CVs greater than 2 m/s. Fifty eight C fibres (C) were also found. None of FA, 40% of SA delta and 52% of C responded to continuous heat. None of C, 47% of FA and 45% of SA delta responded to rapid elevation of temperature. None of C, 20% of FA and 20% of SA delta responded to hydrostatic pressure. None of FA, 83% of SA delta and all of C responded to bradykinin. It was found that 21 of 60 SA delta responded to both types of stimuli that reportedly activate only A (rapid heat and hydrostatic negative pressure) or C (continuous slow heat and bradykinin) nerve fibres and that 29 SA delta responded to slow heating and/or bradykinin, similar to C fibres.
Department of Endodontics, Faculty of Dentistry, Tokyo Medical and Dental University, Japan.
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Ikeda
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Sunakawa
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Suda
D000818:Animals; D001920:Bradykinin / Q000494:pharmacology; D002415:Cats; D003782:Dental Pulp / Q000294:innervation*; D004558:Electric Stimulation; D004594:Electrophysiology; D006358:Hot Temperature; D006874:Hydrostatic Pressure; D008340:Mandibular Nerve / Q000033:anatomy & histology / Q000502:physiology; D009412:Nerve Fibers / Q000187:drug effects / Q000502:physiology*; D009413:Nerve Fibers, Myelinated / Q000187:drug effects / Q000502:physiology; D009431:Neural Conduction; D009475:Neurons, Afferent / Q000502:physiology*; D009619:Nociceptors / Q000502:physiology
D001920:Bradykinin