Impairment of motor coordination in mice after ingestion of aluminum chloride.
The mechanisms of aluminum (Al) neurotoxicity is of increasing interest. Al compounds are known to produce neurological and behavioral abnormalities in some mammalian species. The present study was designed to determine the effects of Al chloride on the skilled motor performance in mice on the rota-rod treadmill. Al chloride, depending on the duration of treatment, produced an impairment of the motor coordination ability in mice.
Sahin
G
G
Department of Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Taşkin
T
T
Benli
K
K
Duru
S
S
D000535:Aluminum / Q000633:toxicity*; D000818:Animals; D003864:Depression, Chemical; D008297:Male; D051379:Mice; D004856:Postural Balance / Q000187:drug effects; D011597:Psychomotor Performance / Q000187:drug effects*
D000535:Aluminum