Cloning and expression of human cDNA encoding phosphatidylinositol transfer protein beta.
cDNA encoding the beta isoform of human phosphatidylinositol transfer protein was cloned from a human brain cDNA library. The deduced sequence of the protein comprised 271 amino acids with a calculated molecular mass of 31,539 Da, and showed 98.1% identity to that of the beta isoform of rat phosphatidylinositol transfer protein. The cDNA hybridized to a 3.4-kb mRNA, which was widely expressed in various human tissues including brain.
Tanaka
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S
Department of Biochemistry, Gunma University School of Medicine, Maebashi, Japan.
Yamashita
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S
Hosaka
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K
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D001921:Brain / Q000378:metabolism; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics*; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000737:chemistry / Q000235:genetics; D015870:Gene Expression; D006801:Humans; D008565:Membrane Proteins; D008969:Molecular Sequence Data; D010716:Phosphatidylinositols / Q000378:metabolism*; D049294:Phospholipid Transfer Proteins; D051381:Rats; D017421:Sequence Analysis
D002352:Carrier Proteins; D018076:DNA, Complementary; D008565:Membrane Proteins; D010716:Phosphatidylinositols; D049294:Phospholipid Transfer Proteins