Intra-articular injection of stromelysin into rabbit knees as a model to evaluate matrix metalloprotease inhibitors.
Goldberg
R L
RL
Research Department, Ciba-Geigy Corporation, Summit, NJ 07901, USA.
Parker
D
D
MacPherson
L
L
Ganu
V
V
Melton
R
R
Hu
S I
SI
Blancuzzi
V
V
Wilson
D
D
Doughty
J
J
Spirito
S
S
D000818:Animals; D001169:Arthritis, Experimental / Q000139:chemically induced* / Q000473:pathology; D002358:Cartilage, Articular / Q000201:enzymology / Q000473:pathology; D005109:Extracellular Matrix / Q000201:enzymology*; D007270:Injections, Intra-Articular; D019278:Matrix Metalloproteinase 3; D008666:Metalloendopeptidases / Q000008:administration & dosage / Q000037:antagonists & inhibitors* / Q000494:pharmacology*; D011480:Protease Inhibitors / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism; D011817:Rabbits
D011480:Protease Inhibitors; D011509:Proteoglycans; D008666:Metalloendopeptidases; D019278:Matrix Metalloproteinase 3