Safety testing of Liberase, a purified enzyme blend for human islet isolation.
Gill
J F
JF
Boehringer Mannheim Biochemicals, Indianapolis, Indiana 46250, USA.
Chambers
L L
LL
Baurley
J L
JL
Ellis
B B
BB
Cavanaugh
T J
TJ
Fetterhoff
T J
TJ
Dwulet
F E
FE
D000707:Anaphylaxis / Q000139:chemically induced; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002469:Cell Separation / Q000379:methods*; D017364:Collagenases / Q000302:isolation & purification / Q000494:pharmacology / Q000633:toxicity*; D006224:Cricetinae; D005260:Female; D005334:Fever / Q000139:chemically induced; D006168:Guinea Pigs; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D007515:Islets of Langerhans / Q000166:cytology* / Q000187:drug effects / Q000502:physiology; D016381:Islets of Langerhans Transplantation; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity; D011749:Pyrogens / Q000633:toxicity; D011817:Rabbits; D012449:Safety
D009153:Mutagens; D011749:Pyrogens; D017364:Collagenases