Corneal vascularization and opacification during long-term use of dipivefrin.
Dipivefrin hydrochloride is a lipophilic prodrug for epinephrine hydrochloride, allowing lower concentration of the drug to achieve the same intraocular pressure lowering effect and having also less harmful effects than epinephrine hydrochloride. However, harmful effects have been associated also with the use of dipivefrin and here we report of a case of corneal vascularization during long-term use of dipivefrin.
Salminen
L
L
Department of Ophthalmology, Tampere University Hospital, Finland.
Krootila
K
K
Helin
H
H
Hakala
T
T
D001762:Blepharitis / Q000139:chemically induced / Q000473:pathology; D003229:Conjunctival Diseases / Q000139:chemically induced / Q000473:pathology; D016510:Corneal Neovascularization / Q000139:chemically induced* / Q000473:pathology; D003318:Corneal Opacity / Q000139:chemically induced* / Q000473:pathology; D004837:Epinephrine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006801:Humans; D006940:Hyperemia / Q000139:chemically induced / Q000473:pathology; D008875:Middle Aged
C015173:dipivefrin; D004837:Epinephrine