[Neuronal migration disorders: clinical-radiological correlation].
We present the correlation of imaging findings with clinical deficits in 34 children with several anomalies of neuronal migration which were studied retrospectively. The cases studied corresponded to: Schizencephaly 10, lissencephaly 4, heterotopy 9, and hemimegalencephaly 2. The diagnosis of the malformations was performed by computerized tomography (CT) in a few patients and by magnetic resonance (MR) in most cases. Among the clinical alterations, psychomotor delay and seizures of difficult control were the most severe, both appeared at early age. The findings observed in this study suggest the correlations between extension, location and gray matter displasticity and the neurological manifestations.
Servicio de Neurología Pediátrica, Hospital Infantil La Paz, Madrid.
D
D
Guillén
I
I
Pascual-Castroviejo
V
V
López Martín
M C
MC
Roche
S I
SI
Pascual-Pascual
J
J
Viaño
V
V
Martínez
D000293:Adolescent; D001927:Brain Diseases / Q000175:diagnosis / Q000503:physiopathology*; D002465:Cell Movement; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D009474:Neurons; D012189:Retrospective Studies; D012640:Seizures / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
Trastornos de la migración neuronal: correlación clínico-radiológica.