A simple method for measuring glomerular filtration rate in dogs.
A technique for measuring glomerular filtration rate (by six-sample plasma clearance) and extracellular fluid volume is described. The results obtained for glomerular filtration rat per extracellular fluid volume with a three blood sample technique are also presented. Concurrently with the blood sample techniques measuring plasma clearance, glomerular filtration rate per extracellular fluid volume was also measured using an external radiation detector and no blood samples. The validity of expressing glomerular filtration rate per extracellular fluid volume (rather than per body weight or surface area) and the clinical utility of the results obtained with the external radiation detector are discussed.
Department of Large Animal Medicine and Surgery, Royal Veterinary College, North Mymms, Hatfield.
A
A
Gleadhill
A M
AM
Peters
A R
AR
Michell
D000818:Animals; D004283:Dog Diseases; D004285:Dogs / Q000502:physiology*; D005110:Extracellular Space / Q000502:physiology; D005919:Glomerular Filtration Rate / Q000662:veterinary*; D007674:Kidney Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000662:veterinary*; D051381:Rats; D012044:Regression Analysis; D016284:Technetium Tc 99m Pentetate
D016284:Technetium Tc 99m Pentetate