[Interpretation of diagnostic data exemplified by tests for identification of Helicobacter pylori in gastric mucosa].
Seven diagnostic tests were employed to detect the infection of gastric mucosa with the H. pylori bacteria, among patients with epigastric pain and dyspeptic complains. The tests' results were compared to the bacteriologic culture. For each test the following criteria were taken into consideration: sensitivity, specificity, positive and negative predictive values. The tests' accuracy was compared with the agreement expected by chance and beyond chance (kappa). For each test the likelihood ratio was calculated for its positive and negative results. The construction of so called diagnostic decision tree was presented, which allows on the evaluation of the diagnostic test and its utility. The best result were obtained from the test, in which the identification of bacteria took place in the histopathologic specimen after its Gram staining. The interpretation of clinical significance of diagnostic data is simplified with the use of likelihood ratio calculated for a positive test result.
Katedry i Kliniki Chirurgii Ogólnej i Naczyń AM w Bydgoszczy.
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Dabrowiecki
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Zegarski
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003663:Decision Trees; D004415:Dyspepsia / Q000209:etiology; D005753:Gastric Mucosa / Q000382:microbiology*; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D016013:Likelihood Functions; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
Interpretacja danych diagnostycznych na przykładzie testów dla identyfikacji Helicobacter pylori w błonie śluzowej zoładka.