In vitro antimicrobial susceptibilities of strains of Yersinia pestis.
The in vitro activities of 14 antimicrobial agents were determined for 78 strains of Yersinia pestis. The most active antibiotics were ceftriaxone and ciprofloxacin, followed by ofloxacin and ampicillin. The agents traditionally used for the treatment of plague (streptomycin, tetracycline, and chloramphenicol) were considerably less active. Azithromycin showed poor activity against all strains.
Wellcome Trust Clinical Research Unit, Cho Quan Hospital, Ho Chi Minh City, Vietnam.
M D
MD
Smith
D X
DX
Vinh
T T
TT
Nguyen
J
J
Wain
D
D
Thung
N J
NJ
White
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010930:Plague / Q000188:drug therapy / Q000382:microbiology; D013045:Species Specificity; D014744:Vietnam; D015010:Yersinia pestis / Q000187:drug effects*
D000900:Anti-Bacterial Agents