[The morphological characteristics of the circulating blood after massive reinfusion in operative surgery].
Intraoperative autologous blood extravasation represents an adequate biogenic medium for prompt and complete blood volume compensation following acute hemorrhage. The efficiency of the procedure is closely related to the functional characteristics of the ATS applied and its potential adaptation to the operative field. Over a 5-year period, autologous blood reinfusion is done in 151 patients with acute intraoperative hemorrhage associated with various types of operative interventions. The hemogram is analyzed in 32 cases undergoing reconstructive surgery of arterial vessels, with massive intraoperative hemorrhage and reinfusion (exceeding 25 per cent of the circulating volume). The quantity of AB represents 92.7 per cent of the blood loss volume; reinfusion is effected using the patient's own ATS. The circulating erythron level (its binding portion) remains within reference limits throughout the full post-reinfusion period; a tendency towards complete correlative dependence between the values of Hb, Er, Ht and the volume of reinfusion done intraoperatively is outlined (r = 0.84-0.92; p < 0.05-0.001). Free hemoglobin concentration in the transfusion product is low (66.8 +/- 24.2 mg/100 ml blood), while in the post-reinfusion circulating blood it quickly returns to normal, at 2 hours--in 87.5 per cent of the samples, and at 6 hours--in 100 per cent (r = 0.66-0.80; p > 0.001). The minimal morphologic changes in AB upon its deposition and reinfusion warrant the assumption that it is the most suitable transfusion medium, contributing to normalization of the hematologic indicators of acute hemorrhage during operative surgery.
Petkov
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D000328:Adult; D001773:Blood Cells / Q000166:cytology*; D001790:Blood Physiological Phenomena; D001804:Blood Transfusion, Autologous / Q000295:instrumentation / Q000706:statistics & numerical data; D006403:Hematologic Tests / Q000706:statistics & numerical data; D006801:Humans; D007430:Intraoperative Care / Q000706:statistics & numerical data; D013514:Surgical Procedures, Operative / Q000706:statistics & numerical data; D013997:Time Factors
Morfologichna kharakteristika na tsirkulirashtata krŭv sled masivna reinfuziia v operativnata khirurgiia.