Optimization of azathioprine therapy by measuring 6-thioguanine nucleotides and methylated mercaptopurine in renal allograft recipients.
Bergan
S
S
Dept of Clinical Pharmacology, National Hospital, University of Oslo, Norway.
Rugstad
H E
HE
Bentdal
O
O
Sødal
G
G
Hartmann
A
A
Klemetsdal
B
B
Aarbakke
J
J
Stokke
O
O
D001379:Azathioprine / Q000008:administration & dosage* / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D006084:Graft Rejection / Q000517:prevention & control; D006150:Guanine Nucleotides / Q000097:blood*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000378:metabolism; D016030:Kidney Transplantation; D015122:Mercaptopurine / Q000031:analogs & derivatives* / Q000097:blood; D008780:Methyltransferases / Q000097:blood; D011446:Prospective Studies; D013873:Thionucleotides / Q000097:blood*
D006150:Guanine Nucleotides; D007166:Immunosuppressive Agents; D013873:Thionucleotides; C003964:6-thioguanylic acid; C010240:6-methylthiopurine; D015122:Mercaptopurine; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D001379:Azathioprine