Onset of resistance to light Hymenolepis nana infection in mice of different strains.
Rapidity in onset of resistance against Hymenolepis nana egg infection after a light primary infection was studied in low and high responder mice challenged at different time intervals. A very rapid acquisition of protection was observed in C57 and a delayed response in C3H mice. In both cases the effect of resistance on weight or worm number was related to the time of challenge infection, suggesting a "race against time" involving host response and parasite development, the outcome varying according to host genetic background.
Istituto di Patologia Sperimentale, Facoltà di Medicina e Chirurgia, Università degli Studi di Cagliari.
M
M
Conchedda
F
F
Gabriele
G
G
Bortoletti
C
C
Palmas
D000818:Animals; D005260:Female; D006925:Hymenolepiasis / Q000235:genetics / Q000276:immunology*; D007113:Immunity, Innate / Q000235:genetics / Q000528:radiation effects; D016867:Immunocompromised Host; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H / Q000235:genetics / Q000276:immunology / Q000469:parasitology*; D008810:Mice, Inbred C57BL / Q000235:genetics / Q000276:immunology / Q000469:parasitology*; D011833:Radiation Injuries, Experimental / Q000276:immunology; D013047:Specific Pathogen-Free Organisms; D013997:Time Factors; D014916:Whole-Body Irradiation / Q000009:adverse effects