An assessment of antibiotic therapy of urinary tract infection in elderly, hospitalised patients.
The aim of the study was to compare the antibiotic treatment actually received by elderly, hospitalised patients with urinary tract infection (UTI) with 'optimal' therapy (as gauged by compliance with antibiotic policy, infecting organism, sensitivity data, patient renal function and cost). UTI was more common in females and in catheterised patients and E.Coli was the commonest pathogen. Trimethoprim and co-amoxiclav were the drugs used most frequently for either empirical or sensitivity data-based treatment. In 96% of infections a drug with appropriate action was administered. Often, however, treatment could have been optimised by substituting a cheaper suitable antibiotic, by standardising duration of therapy and ensuring that doses were adjusted for renal impairment. Savings from the use of 'optimal' therapy were estimated at 17%. There is clearly considerable scope for positive input from the clinical pharmacist in this area.
School of Pharmacy, Robert Gordon University, Schoolhill, Aberdeen.
D J
DJ
McCaig
D
D
Stewart
Y
Y
Harvey
G
G
Downie
C J
CJ
Scott
D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002985:Clinical Protocols; D003365:Costs and Cost Analysis; D005260:Female; D006801:Humans; D008297:Male; D008485:Medical Audit; D012606:Scotland; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000191:economics / Q000209:etiology
D000900:Anti-Bacterial Agents