Methemoglobinemia associated with prilocaine use in neonatal circumcision.
A term, 2500 g infant was circumcised at 2 days of age. The circumcision was uneventful, with no excessive bleeding. Analgesia was provided by prilocaine, 0.5 cc, and subsequently, the neonate developed methemoglobinemia. Alternatives to analgesia with prilocaine are discussed.
Department of Pediatrics, University of Alberta Hospitals, Edmonton, Canada.
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Tse
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Barrington
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Byrne
D000779:Anesthetics, Local / Q000009:adverse effects*; D002944:Circumcision, Male; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced*; D011318:Prilocaine / Q000009:adverse effects*
D000779:Anesthetics, Local; D011318:Prilocaine