[Recurrent annular erythema--cutaneous manifestation of Sjögren syndrome with anti SS-A (Ro) and anti SS-B (La) antibodies].
Eight cases of Sjögren syndrome (SjS) with anti-SS-A and anti-SS-B antibodies are reported. They developed erythema annulare centrifugum-like annular erythema which mainly appeared on the face. Laboratory tests showed similar serologic changes. RA factor, speckled type antinuclear antibody, anti SS-A & SS-B antibodies (DID & ELISA) were observed but complements and anti-double stranded DNA antibodies were not detected. In spite of mild sicca symptoms, sialogram, lip biopsy, Shirmer test and Rose Bengal staining showed typical changes of SjS. It is considered that the recurrent annular erythema is a specific skin manifestation of SjS with anti SS-A/SS-B antibodies.
Usuda
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Division of Dermatology, Social Insurance Chukyo Hospital.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis*; D004890:Erythema / Q000209:etiology* / Q000473:pathology; D005145:Face; D005260:Female; D006801:Humans; D012008:Recurrence; D012859:Sjogren's Syndrome / Q000150:complications* / Q000276:immunology
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies; C035357:SS-B antibodies