Substituted 2-azaspiro[5.3]nonan-1-ones as potent cholesterol absorption inhibitors: defining a binding conformation for SCH 48461.
Schering Plough Research Institute, Kenilworth, New Jersey 07033, USA.
S
S
Dugar
J W
JW
Clader
T M
TM
Chan
H
H
Davis
D000818:Animals; D000924:Anticholesteremic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001384:Azetidines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006224:Cricetinae; D015195:Drug Design; D008958:Models, Molecular; D008968:Molecular Conformation; D013329:Structure-Activity Relationship
D000924:Anticholesteremic Agents; D001384:Azetidines; C095487:1,4-bis(4-methoxyphenyl)-3-(3-phenylpropyl)-2-azetidinone