[Refractory epilepsy in adults and the new antiepileptic drugs: the role of gabapentin].
The features of refractory epilepsies and the role of functional surgery and new antiepileptic drugs is reviewed. Among the latter, gabapentin, a drug with peculiar pharmacokinetic properties, is highlighted as a therapeutic alternative in refractory epilepsies and eventually for epileptic patients without previous treatment. A new type of relationship between the pharmaceutical industry and physicians, that privileges clinical research, is discussed.
Galdames
D
D
Departamento de Neurología Neurocirugía, Facultad de Medicina, Universidad de Chile, Hospital Clínico José Joaquín Aguirre, Santiago de Chile.
Aguilera
L
L
Fauré
E
E
D000085:Acetates / Q000097:blood / Q000627:therapeutic use*; D000588:Amines; D000927:Anticonvulsants / Q000627:therapeutic use*; D002677:Chile; D002986:Clinical Trials as Topic; D003509:Cyclohexanecarboxylic Acids; D004351:Drug Resistance; D004827:Epilepsy / Q000188:drug therapy* / Q000601:surgery; D000077206:Gabapentin; D006801:Humans; D005680:gamma-Aminobutyric Acid
D000085:Acetates; D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin
La epilepsia refractaria del adulto y los antiepilépticos noveles: el rol de la gabapentina.