External beam radiotherapy: hard facts and painful realities.
In comparison to whole brain radiotherapy, local field radiotherapy in a consecutive series of 100 patients with malignant astrocytoma resulted in remarkably less toxicity. Survivorship is not different; the advantage is limited to the 7% long term survivors (defined as living 100% or more beyond median) since toxicity from brain radiation does not occur until a year or more after treatment.
Vick
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Division of Neurology, Evanston Hospital, Northwestern University Medical School, Illinois, USA.
Paleologos
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D001254:Astrocytoma / Q000401:mortality / Q000532:radiotherapy*; D001932:Brain Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods; D015996:Survival Rate