Omeprazole coinduces multiple xenobiotic-metabolizing enzymes in the rat.
Department of Medicine, New York Hospital-Cornell Medical Center, New York, USA.
K
K
Kashfi
A J
AJ
Dannenberg
D000704:Analysis of Variance; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D003600:Cytosol / Q000187:drug effects / Q000201:enzymology; D004386:Duodenum / Q000201:enzymology; D004790:Enzyme Induction; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D014453:Glucuronosyltransferase / Q000096:biosynthesis*; D005982:Glutathione Transferase / Q000096:biosynthesis*; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000201:enzymology*; D008862:Microsomes, Liver / Q000201:enzymology*; D009853:Omeprazole / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D015262:Xenobiotics / Q000378:metabolism*
D004791:Enzyme Inhibitors; D015262:Xenobiotics; D003577:Cytochrome P-450 Enzyme System; D014453:Glucuronosyltransferase; D005982:Glutathione Transferase; D009853:Omeprazole