[Obliterating bronchiolitis with organized pneumonia. Experience in a general hospital].
Bronchiolitis obliterans with organizing pneumonia (BOOP) is a histopathologic entity that has been described in association with numerous clinical conditions. In the 1980s an idiopathic form was described as a definite clinicopathologic entity differentiated from other infiltrative pulmonary processes. We present 7 patients diagnosed of BOOP over the past 6 years and discuss their clinical and radiologic signs as well as their response to steroid treatment. Our patients' evolution was subacute, cough and fever being the main symptoms. Lung function tests revealed a pattern that was predominantly restrictive. Radiology showed 1 or several alveolar infiltrates in all patients; these were migratory in 3. Bilateral pleural effusion with marked eosinophilia in pleural fluid was observed in 1 patient. In another cavitated nodules were present in chest-X-ray, with no evidence of vasculitis in tissue examination. All patients were treated with steroids (mean 10 months) and a low maintenance dose was required in only 1. The remaining patients experienced full recovery.
Barba Romero
M A
MA
Sección de Neumología, Hospital General de Albacete.
Arévalo González
M
M
Aguilar Bargalló
X
X
González Valladares
G
G
Vizcaya Sánchez
M
M
Puras Tellaeche
A
A
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D001989:Bronchiolitis Obliterans / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006769:Hospitals, General; D006801:Humans; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013030:Spain
D000305:Adrenal Cortex Hormones
Bronquiolitis obliterante con neumonía organizada. Experiencia en un hospital general.