[Interleukin 2 receptor (Il-2): structure and function].
Interleukin 2 and its receptor play a crucial role in the growth and differentiation of many cells such as lymphocytes T and B, NK cells, macrophages and monocytes. Il-2 receptor (Il-2R) is involved in Il-2 induced cellular signalling. We discuss the Il-2R structure, function of three distinct subunits and the complex pathways that link the cell surface receptor to the nuclear proto-oncogene production.
Dmoszyńska
A
A
Kliniki Hematologii AM w Lublinie.
Roliński
J
J
D002454:Cell Differentiation / Q000502:physiology; D006801:Humans; D000090063:Proto-Oncogene Mas; D011519:Proto-Oncogenes / Q000502:physiology; D015375:Receptors, Interleukin-2 / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology
C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D015375:Receptors, Interleukin-2
Receptor dla interleukiny 2 (Il-2): struktura i czynność.