Hemostatic activity of organs in declamping shock.
The aim of the study was to determine the haemostatic components activity of organs in declamping shock. The abdominal aorta was cross-clamped below or above renal arteries. No significant changes in tromboplastic and antithrombin activities were found in the kidney, liver, lung, heart and skeletal muscle. Renal cortex and medulla as well as the lungs show higher plasminogen activator activity and considerably higher antiplasmin activity. Diminished fibrinolysis in the kidney and the lung may promote thrombotic complications.
Department of Vascular Surgery and Transplantology, Medical Academy of Bialystok.
S
S
Głowiński
M
M
Gacko
J
J
Głowiński
A
A
Worowska
M
M
Zakrzewski
K
K
Worowski
D000818:Animals; D001777:Blood Coagulation / Q000502:physiology; D003250:Constriction; D004285:Dogs; D005341:Fibrinolysin / Q000378:metabolism; D005342:Fibrinolysis / Q000502:physiology; D006487:Hemostasis / Q000502:physiology*; D007668:Kidney / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008297:Male; D010958:Plasminogen / Q000378:metabolism; D015427:Reperfusion Injury / Q000503:physiopathology*; D012773:Shock, Surgical / Q000503:physiopathology*
D010958:Plasminogen; D005341:Fibrinolysin