[The efficacy of alprazolam in the therapy of panic disorders].
22 patients with panic disorder (diagnosis according to ICD-10) were treated with alprazolam (monotherapy) in a dose of 1-2,5 mg/daily during 6 weeks. Disappearance of panic attacks was observed in 59% of cases while in 27% of patients they arose more rarely. The drug's antipanic action was revealed during second week of treatment. The side-effects were typical for benzodiazepine preparations. No one patient refused of drug administration in connection with side-effects development. Prognostically unfavourable signs were found: the high frequency of panic attacks, the presence of atypical marked permanent symptoms in attack structure, as well as the steady vegetative disturbances presence.
G M
GM
Diukova
O V
OV
Vorob'eva
E P
EP
Petrova
S V
SV
Smirnov
Z N
ZN
Tumalaeva
D000293:Adolescent; D000328:Adult; D000525:Alprazolam / Q000009:adverse effects / Q000627:therapeutic use*; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016584:Panic Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D011599:Psychopathology; D012074:Remission Induction
D014151:Anti-Anxiety Agents; D000525:Alprazolam
Effektivnost' alprazolama v terapii panicheskikh rasstroĭstv.