[The dynamics of the formation of spontaneous autoantibodies to the synaptonemal complex in male mice].
Time-related changes in formation of spontaneous autoantibodies against the synaptonemal complex were studied by indirect immunofluorescence in male mice. Appearance of the spontaneous autoantibodies against the synaptonemal complex coincided with that of the cells containing synaptonemal complexes. The mouse synaptonemal complexes were binding spontaneous autoantibodies of the rabbit and human sera. The synaptonemal complexes of the equine spermatocytes were binding spontaneous autoantibodies of the mouse serum. There was no fluorescence of synaptonemal complexes on preparations of spread rye meiocytes treated with the mouse serum. Antigenic similarity was shown for the synaptonemal complex components in representatives of the different mammalian orders: rodents, odd-toed ungulates, and primates.
S Ia
SIa
Dadashev
G G
GG
Gorach
O L
OL
Kolomiets
Iu S
IuS
Fedotova
D000375:Aging / Q000276:immunology; D000818:Animals; D000831:Animals, Newborn; D001323:Autoantibodies / Q000096:biosynthesis*; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D013090:Spermatocytes / Q000276:immunology; D013573:Synaptonemal Complex / Q000276:immunology*
D001323:Autoantibodies
Issledovanie dinamiki formirovaniia spontannykh autoantitel k sinaptonemnomu kompleksu u samtsov myshi.