Failure to detect dopaminergic neuroblastoma in a mass-screening system.
Dopaminergic neuroblastoma comprised 12% of the patients under 1 year of age, and 83% of the older ones. Seven cases were missed by the mass-screening system performed at age 6 months and were detected after 16 months. Three of these advanced cases were positive only for dopamine. These findings supports our second mass-screening system using dopamine evaluation at age 14 months.
Department of Surgery, Sapporo National Hospital, Hokkaido Cancer Center, Japan.
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Naito
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Takeda
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Hanai
D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004298:Dopamine / Q000652:urine*; D005260:Female; D006719:Homovanillic Acid / Q000652:urine; D006801:Humans; D007223:Infant; D008297:Male; D008403:Mass Screening; D009447:Neuroblastoma / Q000175:diagnosis* / Q000652:urine; D014642:Vanilmandelic Acid / Q000652:urine
D014642:Vanilmandelic Acid; D004298:Dopamine; D006719:Homovanillic Acid