Evaluation of an ACTBP2 ladder composed of 26 sequenced alleles.
A total of 90 alleles found in white Caucasians from North-West Germany were sequenced and 26 alleles chosen to construct a uniform and reliable allelic ladder for the STR system ACTBP2 (SE33). In addition 3 new aspects concerning the sequence structure were observed. Population studies were carried out on white Caucasians (n = 278) from North-West Germany using the new improved ladder. A total of 24 alleles and 14 "interalleles" were found and reproducible results obtained. No significant deviation from Hardy-Weinberg-equilibrium could be observed.
Institute of Legal Medicine, Westfälische Wilhelms-Universität, Münster, Germany.
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Möller
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Schürenkamp
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Brinkmann
D000483:Alleles; D004586:Electrophoresis / Q000379:methods; D005787:Gene Frequency; D005858:Germany; D006801:Humans; D011110:Polymorphism, Genetic; D012015:Reference Standards; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D015203:Reproducibility of Results; D017422:Sequence Analysis, DNA / Q000379:methods*; D009626:Terminology as Topic; D044465:White People / Q000235:genetics*