[Synthesis of stearoyl derivatives of proline-containing hydrophobic peptides].
Hydrophobic stearoyl derivatives of proline-containing di- and tripeptides and their deuterated analogs were synthesized. It was shown by NMR spectroscopy that cis-trans-equilibrium around an X-Pro peptide bond is displaced towards trans-conformers for compounds containing a Ste-Pro fragment as opposed to the compounds containing Boc-Pro or Gly-Pro fragments.
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D000595:Amino Acid Sequence; D004151:Dipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry*; D011392:Proline / Q000032:analysis*; D013229:Stearic Acids / Q000737:chemistry*
D004151:Dipeptides; D009842:Oligopeptides; D013229:Stearic Acids; C031183:stearic acid; D011392:Proline
Sintez stearoil'nykh proizvodnykh prolinsoderzhashchikh gidrofobnykh peptidov.