Intra-articular injection of stromelysin into rabbit knees as a model to evaluate matrix metalloprotease inhibitors.
Research Department, Ciba-Geigy Corporation, Summit, NJ 07901, USA.
R L
RL
Goldberg
D
D
Parker
L
L
MacPherson
V
V
Ganu
R
R
Melton
S I
SI
Hu
V
V
Blancuzzi
D
D
Wilson
J
J
Doughty
S
S
Spirito
D000818:Animals; D001169:Arthritis, Experimental / Q000139:chemically induced* / Q000473:pathology; D002358:Cartilage, Articular / Q000201:enzymology / Q000473:pathology; D005109:Extracellular Matrix / Q000201:enzymology*; D007270:Injections, Intra-Articular; D019278:Matrix Metalloproteinase 3; D008666:Metalloendopeptidases / Q000008:administration & dosage / Q000037:antagonists & inhibitors* / Q000494:pharmacology*; D011480:Protease Inhibitors / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism; D011817:Rabbits
D011480:Protease Inhibitors; D011509:Proteoglycans; D008666:Metalloendopeptidases; D019278:Matrix Metalloproteinase 3