The immunopathogenesis of cutaneous T-cell lymphoma.
A perplexing array of immune abnormalities have been described in cutaneous T-cell lymphoma. This article discusses the mechanisms underlying these immune abnormalities. The immune processes that have become disordered are examined with reference to the steps involved in generating the disease and how these steps can be corrected therapeutically.
Rook
A H
AH
Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, USA.
Heald
P
P
D016207:Cytokines / Q000378:metabolism; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D012878:Skin Neoplasms / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D016176:T-Lymphocyte Subsets; D013601:T-Lymphocytes / Q000473:pathology
D016207:Cytokines