Divalproex sodium as a treatment for borderline personality disorder.
Divalproex sodium was given to a series of individuals with the diagnosis of borderline personality disorder. Objective measures of agitation and anxiety were then used to assess the effect of divalproex sodium on such symptoms. Data were collected on the subjects and the amount of time spent in the agitated state was evaluated. We found that divalproex sodium reduced agitation in our subjects.
Wilcox
J A
JA
MECCA, Iowa City, Iowa, USA.
D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D018692:Antimanic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001143:Arousal / Q000187:drug effects; D001883:Borderline Personality Disorder / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D016896:Treatment Outcome; D014635:Valproic Acid / Q000009:adverse effects / Q000627:therapeutic use*
D000927:Anticonvulsants; D018692:Antimanic Agents; D014635:Valproic Acid