Polycystic ovarian disease: a new look at an old subject.
The understanding of the pathogenesis of polycystic ovary syndrome has advanced significantly, and improvements have been made in the treatment of the commonly associated symptoms. New data continue to implicate a derangement in insulin secretion and metabolism as a cause of the disease. Therapeutic regimens for those patients unsuccessfully treated by traditional approaches have been further validated, especially for the treatment of infertility. Future therapeutic strategies involving the retrieval of unstimulated, immature oocytes that are fertilized and matured in vitro are a possibility.
Udoff
L
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Department of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore, USA.
Adashi
E Y
EY
D005260:Female; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology / Q000628:therapy