Anti-tumour-promoting glyceroglycolipids from the green alga, Chlorella vulgaris.
Two new monogalactosyl diacylglycerols were isolated from the freshwater green alga, Chlorella vulgaris, as anti-tumour promoters, together with three monogalactosyl diacylglycerols and two digalactosyl diacylglycerols. The new monogalactosyl diacylglycerol containing (7Z,10Z)-hexadecadienoic acid showed a more potent inhibitory effect toward tumour promotion than the other glycerolipids isolated.
Faculty of Pharmaceutical Sciences, Nagoya City University, Japan.
T
T
Morimoto
A
A
Nagatsu
N
N
Murakami
J
J
Sakakibara
H
H
Tokuda
H
H
Nishino
A
A
Iwashima
D016588:Anticarcinogenic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D002240:Carbohydrate Sequence; D002708:Chlorella / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D005990:Glycerol / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006017:Glycolipids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008969:Molecular Sequence Data
D016588:Anticarcinogenic Agents; D006017:Glycolipids; D005990:Glycerol