Ion channels and pumps in cardiac function.
Ion channels and pumps are intrinsic membrane proteins that regulate the membrane potential and transport of ions and substrates, controlling excitation and excitation-contraction coupling. Several have been cloned and an example of our progress in structure-function correlation is the identification of the pore region of the Na channel.
Fozzard
H A
HA
Department of Pharmacological & Physiological Sciences, University of Chicago, IL 60637, USA.
Lipkind
G
G
D000818:Animals; D001693:Biological Transport, Active; D006321:Heart / Q000502:physiology*; D006801:Humans; D007473:Ion Channels / Q000502:physiology*; D008958:Models, Molecular
D007473:Ion Channels