title: Drug removal in continuous haemofiltration and haemodialysis.
abstract: Although both continuous haemofiltration and continuous haemodialysis are techniques routinely employed in the management of critically ill patients, deciding on a drug dosing regimen is often difficult. This article highlights the factors influencing drug removal by both processes, the difficulties associated with the interpretation of research in this area and offers a number of approaches which can be used when selecting a dosing regimen for a patient receiving one of these therapies.
authors.affiliation: Department of Pharmacy, University of Brighton.
authors.forename: J G
authors.initials: JG
authors.lastname: Davies
authors.forename: J C
authors.initials: JC
authors.lastname: Kingswood
authors.forename: P
authors.initials: P
authors.lastname: Sharpstone
authors.forename: M K
authors.initials: MK
authors.lastname: Street
mesh_terms: D003404:Creatinine / Q000378:metabolism; D016903:Drug Monitoring; D006440:Hemofiltration; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D010599:Pharmacokinetics; D006435:Renal Dialysis
chemical_list: D004364:Pharmaceutical Preparations; D003404:Creatinine