title: Organic halogens in the environment: studies of environmental biodegradability and human exposure.
abstract: Organic halogens from chlorobleaching of kraft pulp were not as biorecalcitrant as has been assumed. Fifty percent were removed during biotreatment of wastewater, and 50% of the remaining organohalogens faded in fresh water ecosystems in 200 to 400 days. Molecular size seemed not to hinder biodegradation up to sizes of approximately 2000 daltons. Anoxic biodegradation was of prime importance for halomineralization of pulp bleaching organohalogens but could also lead to toxic metabolites such as vinyl chloride from tri- and tetrachloroethene in anoxic soil. Indigenous soil microbes were unable to clean old organohalogen pollution but had converted chlorophenols into polymeric substances, chlorohumus, which were found bioaccumulable by earthworms in spite of the large (up to 5000 g/mole) molecular sizes. Because of the danger of formation of toxic metabolites, the biochemistry of the xenobiotic degradation must be elucidated before active bioremediation is practiced on polluted soil or water. Groundwater pollution by chlorophenols led to increased disease among the exposed population in one well-studied case. Two further cases of potential environmental health impact are described.
authors.affiliation: Department of Applied Chemistry and Microbiology, University of Helsinki, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Salkinoja-Salonen
authors.forename: J
authors.initials: J
authors.lastname: Uotila
authors.forename: J
authors.initials: J
authors.lastname: Jokela
authors.forename: M
authors.initials: M
authors.lastname: Laine
authors.forename: E
authors.initials: E
authors.lastname: Saski
mesh_terms: D001673:Biodegradation, Environmental; D002733:Chlorophenols / Q000378:metabolism; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000378:metabolism*; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000378:metabolism*; D012989:Soil Pollutants / Q000378:metabolism; D018508:Water Purification
chemical_list: D002733:Chlorophenols; D004785:Environmental Pollutants; D006846:Hydrocarbons, Halogenated; D012989:Soil Pollutants