Molecular inactivation. Spatially and temporally defined molecular knockouts.
Most monoclonal antibodies do not functionally inactivate the antigen they recognize. This limitation can be overcome by localized chromophore-assisted laser inactivation (CALI) of specific antibody-linked proteins.
Müller
B K
BK
Abteilung Physikalische Biologie, Max-Planck-Institute für Entwicklungsbiologie, Tübingen, Germany.
Bonhoeffer
F
F
D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry* / Q000276:immunology; D000941:Antigens / Q000737:chemistry* / Q000276:immunology; D004396:Coloring Agents; D007834:Lasers; D011489:Protein Denaturation
D000911:Antibodies, Monoclonal; D000941:Antigens; D004396:Coloring Agents