Analysis of sulfamethazine in the presence of sulfamerazine or sulfadiazine by first-derivative photochemically induced fluorescence.
A first-derivative photochemically-induced fluorescence method is proposed for the determination of sulfamethazine (SMTZ) in the presence of sulfamerazine (SMRZ) or sulfadiazine (SDZ). Linear calibration plots were obtained for SMTZ in SMTZ-SMRZ or SMTZ-SDZ binary mixtures with correlation coefficients larger than 0.999. For SMTZ the lower limits of detection were 7-13 ppb. Recoveries of 91-114% were obtained in the analysis of SMTZ in pharmaceutical formulations.
Sanchez Pena
M
M
Department of Analytical Chemistry, Faculty of Sciences, University of Extramadura, Badajoz, Spain.
Acedo
M J
MJ
Salinas
F
F
Mahedero
M C
MC
Aaron
J J
JJ
D000890:Anti-Infective Agents / Q000032:analysis* / Q000737:chemistry; D004347:Drug Interactions; D008027:Light; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013411:Sulfadiazine / Q000737:chemistry*; D013416:Sulfamerazine / Q000737:chemistry*; D013418:Sulfamethazine / Q000032:analysis* / Q000737:chemistry
D000890:Anti-Infective Agents; D013411:Sulfadiazine; D013418:Sulfamethazine; D013416:Sulfamerazine