title: [Chronic demyelinating polyneuropathy associated with multiple sclerosis: a patient with two diseases].
abstract: We studied the clinical, paraclinical and laboratory findings of a patient suffering from multiple sclerosis (MS) with chronic demyelinating polyneuropathy. As well as being a new case of demyelination of the central and peripheral nervous system not normally associated with the presence of antiganglionic antibodies, our patient presented clinical signs distinct from each disease with the characteristic abnormalities of cerebrospinal fluid (CSF) (cytological albumin dissociation at the moment when an outbreak appeared at the peripheral level and an increase in intrathecal secretion when the outbreak was at the central nervous system level). Demyelinating diseases of the central and peripheral nervous systems are a field of great interest in trying to find the antigenic bull's eye for MS.
authors.affiliation: Departamento de Neurologia, Hospital Universitario, Sevilla.
authors.forename: M A
authors.initials: MA
authors.lastname: Quesada
authors.forename: G
authors.initials: G
authors.lastname: Izquierdo
authors.forename: J
authors.initials: J
authors.lastname: Bautista
authors.forename: I
authors.initials: I
authors.lastname: Chinchón
mesh_terms: D000328:Adult; D000418:Albumins / Q000134:cerebrospinal fluid; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000150:complications* / Q000188:drug therapy; D017933:Peripheral Nervous System / Q000503:physiopathology; D013497:Sural Nerve / Q000648:ultrastructure
chemical_list: D000418:Albumins; D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone
vernacular_title: Polineuropatia crónica desmielinizante asociada a esclerosis múltiple. Un paciente y dos enfermedades.