The effect of temperature on the stability of the synthetic SPf(66)n malaria vaccine.
We hereby report on the effect of temperature on the physico-chemical and immunogenic characteristics and stability of the SPf(66)n synthetic malaria vaccine. The pattern of polymerization, the adsorption to aluminium hydroxide and the immunological properties of these vaccine groups were not significantly affected.
López
M C
MC
Instituto de Parasitologia y Biomedicina López Neyra, CSIC, Granada, Spain.
Thomas
M C
MC
Olivares
M
M
Alonso
P
P
Alonso
C
C
D000595:Amino Acid Sequence; D000818:Animals; D000953:Antigens, Protozoan; D003906:Developing Countries; D004355:Drug Stability; D006801:Humans; D017780:Malaria Vaccines / Q000737:chemistry*; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000276:immunology*; D011634:Public Health; D013696:Temperature; D014614:Vaccines, Synthetic / Q000737:chemistry*
D000953:Antigens, Protozoan; D017780:Malaria Vaccines; D014614:Vaccines, Synthetic