New insights into membrane dynamics from the analysis of cell surface interactions by physical methods.
The physical, chemical and mechanical properties of the cell surface can be probed using a variety of microscopy-based techniques. The movements of membrane components are currently being characterized, and recent experiments have begun to define the structural origins of these modes of transport at a molecular level. However, explicit relationships between new knowledge of membrane structure and complex, linked functions, such as signal transduction and adhesion, remain elusive.
Sheets
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Department of Chemistry, University of North Carolina, Chapel Hill 27599-3290, USA.
Simson
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Jacobson
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D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002448:Cell Adhesion / Q000502:physiology*; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
D008565:Membrane Proteins