Bioactivity of certain medicinal latexes used by the Ese'ejas.
Latexes from Croton erythrochilus, Ficus inspidia and Sapium marmieri used traditionally as medicinal by the Ese'ejas were analyzed for bioactivity. The assays run were: the brine shrimp toxicity microplate bioassay, the wheat rootlet growth inhibition and the DNA-methyl green bioassay. The three latexes showed cytotoxicity to the brine shrimp and concentration-related growth inhibition. No interaction with the DNA-methyl green complex was observed with any of the three latex samples. The field bioassays described has demonstrated to be useful for supporting ethnobotanical information.
Mongelli
E
E
Cátedra de Biotecnología y Microbiología Industrial, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín, Argentina.
Desmarchelier
C
C
Giulietti
A
A
Coussio
J
J
Ciccia
G
G
D000818:Animals; D001118:Argentina; D001156:Artemia / Q000187:drug effects; D001681:Biological Assay; D003124:Colorimetry; D004247:DNA / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D007840:Latex / Q000633:toxicity*; D007928:Lethal Dose 50; D008739:Methyl Green / Q000737:chemistry; D018517:Plant Roots / Q000187:drug effects / Q000254:growth & development; D010946:Plants, Medicinal; D014908:Triticum / Q000187:drug effects
D007840:Latex; D008739:Methyl Green; D004247:DNA