Urethral condylomata, due to human papilloma virus (HPV) type 6/11., associated with transitional cell tumors in the bladder and ureter. A case report.
Condylomata in the urethra usually occur as a complication to genital warts on the external genitals and are most often situated in the distal part of the urethra. This is a report of a male patient with recurring papillomatous transitional cell tumors, stage Ta and T1, grade 2 and 3 in the bladder and the right ureter, who presented with extensive condylomatosis in the urethra from the meatus to the verumontanum, without simultaneous presence of condylomata at the external genitals. Condylomatous fragments were also present in the TUR specimen from the bladder, but may have been displaced from the urethra during cystoscopy. Using PCR technique and in situ hybridisation, HPV types 6/11 were detected in the condylomata, but no virus was present in the transitional cell tumors.
Olsen
S
S
Department of Urology, University of Aarhus, Skejby Hospital, Denmark.
Marcussen
N
N
Jensen
K M
KM
Lindeberg
H
H
D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000473:pathology / Q000821:virology*; D003218:Condylomata Acuminata / Q000473:pathology*; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000473:pathology*; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000473:pathology*; D014516:Ureteral Neoplasms / Q000473:pathology / Q000821:virology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000821:virology*