title: Quality of life in patients with intermittent claudication.
abstract: OBJECTIVE
  As intermittent claudication (IC) infrequently progresses to limb loss many clinicians adopt a conservative approach to treatment. Recently percutaneous transluminal angioplasty (PTA) has been applied to patients with IC. If this were to become the first line treatment for IC it would have major implications in terms of hospital facilities as well as cost. A measure is required, therefore, to decide on rationing of limited financial resources. "Quality of life" may be more influential in determining demand on services since objective medical criteria cannot give an insight into the patients feelings of well being.
  
  
  METHODS
  We applied the Nottingham Health Profile, by post, to a group of claudicants and age/sex matched controls. 70% responded from both groups. Claudicants who had recently received intervention were excluded, as were controls complaining of any leg pains on walking.
  
  
  RESULTS
  The results showed that claudicants have greater perceived problems in the areas of energy, pain, emotional reactions, sleep, and physical mobility compared to controls (p < 0.05; Mann-Whitney Test). This was reflected by a significantly greater positive response rate to problems with activities of daily living (0.05 > p > 0.02; Chi-square Test) in the claudicant group.
  
  
  CONCLUSIONS
  Because of the cost and resource implications of introducing measures such as PTA to the treatment of vast numbers of patients with IC, we suggest that trials are needed to compare various treatments using quality of life measurements in addition to traditional efficacy/safety parameters.
authors.affiliation: Department of Vascular Surgery, Queen Elizabeth Hospital, Edgbaston, Birmingham, U.K.
authors.forename: H S
authors.initials: HS
authors.lastname: Khaira
authors.forename: R
authors.initials: R
authors.lastname: Hanger
authors.forename: C P
authors.initials: CP
authors.lastname: Shearman
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004644:Emotions; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010146:Pain; D011788:Quality of Life; D012890:Sleep