title: [A comparison of changes of cerebrovascular oxygen saturation in retrograde and selective cerebral perfusion during aortic arch surgery].
abstract: To evaluate the effect of retrograde cerebral perfusion (RCP) and selective cerebral perfusion (SCP) on brain protection, changes of cerebrovascular oxygen saturation (rSO2) were studied in 14 patients with aortic arch reconstruction during the procedure. The rSO2 was monitored with spectroscopy instrument (Invos 3100, Somanetics). The mean value of rSO2 measured just before cardiopulmonary bypass was 65.9 +/- 6.2% in 7 patients with RCP, and was 64.9 +/- 4.7% in 7 patients with SCP. The value of rSO2 during core cooling of cardiopulmonary bypass was increased step by step. Although RCP time with a mean of 38.9 +/- 9.7 min was statistically shorter than SCP time (80.7 +/- 45.1 min), the mean value of rSO2 during cerebral protection in RCP group was decreased from 80.3 +/- 8.1% to 63.4 +/- 10.2%, lowest 46% with a ratio of 21.1%. In contrast, the mean value of rSO2 in SCP group was well maintained from 79.9 +/- 6.5 to 75.6 +/- 6.8%, lowest 63% with a ratio of 5.4%. Although no neurological deficits were recognized after operation in both groups, rSO2 in SCP group was sustained above the control value (65% just before cardiopulmonary bypass) but rSO2 in RCP group was decreased below the control value after 35 min. So we conclude that with regard to brain protection assessed from rSO2 measured by Invos 3100 cerebral oximeter, there is no time limitation of SCP during the procedure but RCP had a limit of the duration.
authors.affiliation: Division of Cardiovascular Surgery, Hyogo Brain and Heart Center at Himeji, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Higami
authors.forename: S
authors.initials: S
authors.lastname: Kozawa
authors.forename: T
authors.initials: T
authors.lastname: Asada
authors.forename: N
authors.initials: N
authors.lastname: Mukohara
authors.forename: H
authors.initials: H
authors.lastname: Obo
authors.forename: K
authors.initials: K
authors.lastname: Gan
authors.forename: K
authors.initials: K
authors.lastname: Iwahashi
authors.forename: K
authors.initials: K
authors.lastname: Ogawa
mesh_terms: D000368:Aged; D001013:Aorta, Thoracic / Q000601:surgery; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D001921:Brain / Q000378:metabolism*; D002315:Cardiopulmonary Bypass; D005260:Female; D006801:Humans; D008297:Male; D010100:Oxygen / Q000378:metabolism*; D010477:Perfusion / Q000379:methods*; D013057:Spectrum Analysis / Q000295:instrumentation
chemical_list: D010100:Oxygen