Copro-antibody in calves from dams vaccinated against Salmonella typhimurium.
Calves received colostrum either with (positive colostrum) or without (negative colostrum) anti-Salmonella typhimurium antibodies. Regarding the detectability of copro-antibodies, the following observations have been made. In calves that had been given positive colostrum on day 4 post natum (p.n.), copro-antibodies were detectable over 7 days, while in those that had received positive colostrum on day 1 p.n. copro-antibodies were detectable over 45 days. After supplying highly positive colostrum, copro-antibodies were found over a period of 8 weeks, and after supplying weakly positive colostrum, they were found over a period of 5 weeks. It is concluded that serum antibodies are transferred to the intestine for maximum local protection, and that there exists a preference for the intestinal system regarding the distribution of salmonella antibodies. Challenge infection on day 5 p.n. of calves that had received highly positive colostrum resulted in a copro-antibody gap that reached the limit of detectability in two calves that were excreting salmonellas. Challenge infection of calves that had received negative colostrum provoked a local IgM and IgA antibody response.
Staak
C
C
Federal Institute for Health Protection of Consumers and Veterinary Medicine (BGVV), Berlin, Germany.
Luge
E
E
D000818:Animals; D000831:Animals, Newborn; D000907:Antibodies, Bacterial / Q000032:analysis*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology* / Q000517:prevention & control; D003126:Colostrum / Q000276:immunology; D005243:Feces / Q000737:chemistry; D005260:Female; D007112:Immunity, Maternally-Acquired; D012481:Salmonella Infections, Animal / Q000276:immunology* / Q000517:prevention & control; D012486:Salmonella typhimurium / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary
D000907:Antibodies, Bacterial