Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test.
Tateishi
T
T
Graham
S G
SG
Krivoruk
Y
Y
Wood
A J
AJ
D000328:Adult; D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D001944:Breath Tests; D002250:Carbon Radioisotopes; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects* / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004917:Erythromycin / Q000493:pharmacokinetics*; D006801:Humans; D008297:Male; D006899:Mixed Function Oxygenases / Q000187:drug effects* / Q000378:metabolism; D009853:Omeprazole / Q000494:pharmacology*; D012016:Reference Values
D000897:Anti-Ulcer Agents; D002250:Carbon Radioisotopes; D004791:Enzyme Inhibitors; D004917:Erythromycin; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human; D009853:Omeprazole