title: Endosaccular treatment of inoperable intracranial aneurysms with platinum coils.
abstract: Endosaccular packing of inoperable aneurysms with electrolytic platinum coils was performed in 50 patients. Complete embolization of the aneurysms was achieved in 100% of small, 95% of large and 85% of giant aneurysms, with combined procedural and periprocedural morbidity and mortality rates of 6 and 4%, respectively. Follow-up angiography of 42 aneurysms demonstrated some degree of refilling in 17% of small, 19% of large and 50% of giant aneurysms. The risks associated with the procedure were similar in aneurysms of the carotid and vertebrobasilar circulations. This treatment should therefore be considered for all inoperable aneurysms and particularly for aneurysms involving the posterior circulation. Its long-term efficacy remains uncertain.
authors.affiliation: Department of Neuroradiology, Radcliffe Infirmary, Oxford, UK.
authors.forename: J V
authors.initials: JV
authors.lastname: Byrne
authors.forename: C B
authors.initials: CB
authors.lastname: Adams
authors.forename: R S
authors.initials: RS
authors.lastname: Kerr
authors.forename: A J
authors.initials: AJ
authors.lastname: Molyneux
mesh_terms: D000328:Adult; D000368:Aged; D001488:Basilar Artery / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010984:Platinum; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000401:mortality; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy; D015996:Survival Rate; D016896:Treatment Outcome; D014711:Vertebral Artery / Q000000981:diagnostic imaging
chemical_list: D010984:Platinum