Complications and effectiveness of gastrostomy feedings in pediatric cancer patients.
OBJECTIVE
The objective of this study was to assess the complications and efficacy of gastrostomy (GT) feedings in pediatric cancer patients.


METHODS
We reviewed the medical records of 33 pediatric cancer patients who received enteral nutrition via a GT.


RESULTS
Median age was 9.4 years (range, 1-19.8 years), and 28 of the 33 patients had solid tumors. Seventeen patients had a significant weight loss (median, 8.5%) and therapy-related weight loss was anticipated in 16 patients. The GT device was placed an average of 5.5 months after diagnosis. Twenty-five patients were fed via a tube and eight via a button device. The tube was placed surgically in 21 cases (including all eight button types) and endoscopically in 12. Nutritional support lasted a median of 9.5 months. One or more complications occurred in 30 patients and were categorized as (a) insertion site reactions (inflammation, 23; infection/colonization, 14; exuberant granulation tissue, 6); (b) mechanical problems (leaking, 3; obstruction, 2; breakage, 1; accidental dislodgement, 2); (c) insertion site bleeding, 8; and (d) feeding intolerance, 12. Only one insertion site cellulitis progressed to a systemic infection. All eight patients with a button GT experienced insertion site complications, with local infection occurring significantly more often in patients with the button than in those with the tube GT. There were no significant associations between insertion technique and type of complication. Twenty-seven patients (82%) achieved or maintained ideal body weight with this intervention.


CONCLUSIONS
GT feeding was associated with minor complications, but permitted effective nutritional support for pediatric cancer patients.
Mathew
P
P
Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, TN 38101-0318, USA.
Bowman
L
L
Williams
R
R
Jones
D
D
Rao
B
B
Schropp
K
K
Warren
B
B
Klyce
M K
MK
Whitington
G
G
Hudson
M
M
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004750:Enteral Nutrition / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D005260:Female; D005774:Gastrostomy / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007223:Infant; D008297:Male; D009369:Neoplasms / Q000628:therapy*