[Value of several hormone indicators and cyclic nucleotides in the assessment and prognosis of resistance to acute hypoxia during operator activities].
A study was performed in which 16 healthy volunteers, aged 25-40 years, worked in a two-dimensional tracking simulator and breathed a mixture containing 9-12% oxygen. This led to a higher incretion of cortisol, insulin, somatotropin, a greater renal excretion of epinephrine, norepinephrine, and a higher content of cAMP in lymphocytes, plasma and urine. The subjects with a higher insulin in plasma and renal excretion of catecholamines showed a longer time of tolerance to the above exposure which varied from 50 to 120 min. The high tolerance was combined with a greater activity of the sympathoadrenal system, incretion of cortisol and cAMP in lymphocytes. A significant correlation was demonstrated between cAMP in the above environments both before and after exposure.
Bobrovnitskiĭ
I P
IP
Petrova
T V
TV
Iakovleva
I P
IP
Kalinkin
S V
SV
D000208:Acute Disease; D000328:Adult; D000337:Aerospace Medicine; D004837:Epinephrine / Q000652:urine; D004912:Erythrocytes / Q000378:metabolism; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D000860:Hypoxia / Q000097:blood / Q000378:metabolism*; D007328:Insulin / Q000097:blood*; D008297:Male; D009638:Norepinephrine / Q000652:urine; D009712:Nucleotides, Cyclic / Q000097:blood / Q000378:metabolism* / Q000652:urine; D009790:Occupations
D007328:Insulin; D009712:Nucleotides, Cyclic; D013006:Growth Hormone; D006854:Hydrocortisone; D009638:Norepinephrine; D004837:Epinephrine
Informativnost' nekotorykh gormonal'nykh pokazateleĭ i tsiklicheskikh nukleotidov v otsenke i prognoze ustoĭchivosti k vozdeĭstviiu ostroĭ gipoksii pri operatorskoĭ deiatel'nosti.