title: Endoscopic collagen injection therapy in elderly women with type I stress urinary incontinence.
abstract: OBJECTIVE
  The safety and efficacy of collagen injection therapy for the treatment of type I stress urinary incontinence were determined.
  
  
  METHODS
  A total of 12 women 68 to 85 years old (mean age 76) with type I stress urinary incontinence underwent collagen injection. Incontinence was subjectively categorized as grades 0 to 3, and Valsalva leak point pressures were measured before and after injection.
  
  
  RESULTS
  At a mean of 10.3 months (range 3 to 24) 10 of the 12 women (83%) were cured, while the remaining 2 noticed subjective improvement in incontinence. Average number of injections per patient was 1.25 (1 injection in 9 and 2 in 3), average total collagen injected per patient was 2.2 cc (range 1.0 to 3.5) and average increase in Valsalva leak point pressure after collagen injection was 22 cm. water (range 0 to 40).
  
  
  CONCLUSIONS
  Collagen injection appears to be an effective alternative method for the treatment of type I stress urinary incontinence in elderly women.
authors.affiliation: Section of Urology, University of Michigan Medical Center, Veteran's Administration Medical Center, Ann Arbor, USA.
authors.forename: G J
authors.initials: GJ
authors.lastname: Faerber
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003094:Collagen / Q000008:administration & dosage*; D003558:Cystoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D014550:Urinary Incontinence, Stress / Q000145:classification / Q000628:therapy*
chemical_list: D003094:Collagen