Urticaria associated with thyrotoxicosis.
We report a patient with chronic urticaria which was closely associated with elevated levels of thyroxine. The urticaria responded poorly to antihistamines and only partially to systemic steroids, but resolved consistently when the thyroxine level was reduced to normal. The mechanism for the association may involve modulation of the cyclic AMP levels within mast cells.
Henderson
C A
CA
Department of Dermatology, Walsgrave Hospital, Coventry, UK.
Highet
A S
AS
D000328:Adult; D002231:Carbimazole / Q000627:therapeutic use; D002908:Chronic Disease; D005260:Female; D006801:Humans; D013971:Thyrotoxicosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013974:Thyroxine / Q000097:blood; D014581:Urticaria / Q000097:blood / Q000150:complications*
D002231:Carbimazole; D013974:Thyroxine