Postoperative nausea vomiting (PONV): influence of bowel manipulation during intraabdominal surgery.
This study does not confirm the hypothesis that "bowel manipulation during intraabdominal surgery may release 5 HT3 to stimulate the vomiting center via the vagus nerve". Thus routine prophylactic use of 5 HT3 receptor antagonist is probably not necessary, especially in Thai patients whose PONV is not distinct both in incidence and intensity of emesis.
Sirivanasandha
P
P
Department of Anesthesiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
D000293:Adolescent; D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D013505:Digestive System Surgical Procedures; D005260:Female; D005767:Gastrointestinal Diseases / Q000601:surgery*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000453:epidemiology / Q000209:etiology*; D011183:Postoperative Complications / Q000453:epidemiology; D012307:Risk Factors; D013514:Surgical Procedures, Operative / Q000009:adverse effects / Q000379:methods; D014839:Vomiting / Q000453:epidemiology / Q000209:etiology*