title: Effect of interferon alpha IIb on the activity of sialyltransferase in testis homogenates of adult rats.
abstract: Interferon alpha IIb was injected to adult male rats at doses ranging from 10,000 to 200,000 units. Animals were dissected at intervals of 12 h, 24 h, and 5 days. The activity of the enzyme sialyltransferase in testis homogenates was estimated. In the majority of experiments enzyme activity decreased in comparison to controls.
authors.affiliation: Male Fertility Laboratory, Beilinson Medical Center, Petah Tikva, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Singer
authors.forename: A
authors.initials: A
authors.lastname: Cohen
authors.forename: H
authors.initials: H
authors.lastname: Levinsky
authors.forename: P
authors.initials: P
authors.lastname: Raanani
authors.forename: B B
authors.initials: BB
authors.lastname: Luria
authors.forename: R
authors.initials: R
authors.lastname: Weissenberg
authors.forename: M
authors.initials: M
authors.lastname: Lahav
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D011994:Recombinant Proteins; D012799:Sialyltransferases / Q000187:drug effects / Q000378:metabolism*; D013737:Testis / Q000201:enzymology*; D013997:Time Factors
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D012799:Sialyltransferases