Treatment of adenoviral pneumonitis with intravenous ribavirin and immunoglobulin.
A 67 year old woman developed a severe adenoviral pneumonitis whilst receiving immunosuppressive therapy. She showed clinical and radiological evidence of a response to treatment with nebulised and intravenous ribavirin and intravenous pooled normal human immunoglobulin. To our knowledge this is the first time that such a therapeutic approach has been used in the treatment of a condition which normally carries a very high mortality.
Sabroe
I
I
Department of Infectious Diseases and Bacteriology, Royal Postgraduate Medical School, London, UK.
McHale
J
J
Tait
D R
DR
Lynn
W A
WA
Ward
K N
KN
Shaunak
S
S
D000257:Adenoviridae Infections / Q000188:drug therapy*; D000368:Aged; D000998:Antiviral Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007275:Injections, Intravenous; D011024:Pneumonia, Viral / Q000188:drug therapy*; D012254:Ribavirin / Q000008:administration & dosage*
D000998:Antiviral Agents; D016756:Immunoglobulins, Intravenous; D012254:Ribavirin