title: Effect of D-400, a herbomineral preparation on lipid profile, glycated haemoglobin and glucose tolerance in streptozotocin induced diabetes in rats.
abstract: This study was undertaken to investigate D-400, a herbomineral formulation in streptozotocin induced diabetes in rats. Glycated haemoglobin, lipid profile and glucose tolerance test were studied. D-400 has an established hypoglycaemic effect in alloxan induced diabetes in rats as well as in non-insulin dependent diabetes mellitus patients. D-400 treated group showed lower glycated haemoglobin, triglycerides and higher HDL levels. The hyperglycaemic response was blunted after administration of oral glucose in the same group.
authors.affiliation: R&D Centre, Himalaya Drug Co., Makali, Bangalore.
authors.forename: S K
authors.initials: SK
authors.lastname: Mitra
authors.forename: S
authors.initials: S
authors.lastname: Gopumadhavan
authors.forename: T S
authors.initials: TS
authors.lastname: Muralidhar
authors.forename: S D
authors.initials: SD
authors.lastname: Anturlikar
authors.forename: M B
authors.initials: MB
authors.lastname: Sujatha
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000378:metabolism*; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008055:Lipids / Q000097:blood*; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D008055:Lipids; D010936:Plant Extracts; C095293:D 400