title: [Evolutionary programming for finding "structure-activity" relationships in a series of 3-phenoxychromone and 3-phenoxy-4-hydroxycoumarin derivatives].
abstract: Based on a set of compounds possessing hypolipidemic activity, it was demonstrated that evolutionary algorithms can be successfully used to compile an informative set of molecular parameters. The parameter sets selected using the method of potential functions allowed correct prediction of the activity of test molecules.
authors.forename: I V
authors.initials: IV
authors.lastname: Tetko
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Tanchuk
authors.forename: S A
authors.initials: SA
authors.lastname: Vasil'ev
authors.forename: V P
authors.initials: VP
authors.lastname: Khilia
authors.forename: G I
authors.initials: GI
authors.lastname: Poda
authors.forename: A I
authors.initials: AI
authors.lastname: Luĭk
mesh_terms: D015110:4-Hydroxycoumarins / Q000737:chemistry* / Q000494:pharmacology; D000465:Algorithms; D002867:Chromones / Q000737:chemistry* / Q000494:pharmacology; D000960:Hypolipidemic Agents / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: C097882:3-phenoxychromone; D015110:4-Hydroxycoumarins; D002867:Chromones; D000960:Hypolipidemic Agents; C097883:3-phenoxy-4-hydroxycoumarin
vernacular_title: Evoliutsionnoe programmirovanie dlia vyiavleniia zakonomernosteĭ "struktura-aktivnost" v riadu proizvodnykh 3-fenoksikhromona i 3-fenoksi-4-gidroksikumarina.