title: Postnatal development of the projection from the medial superior olive to the inferior colliculus in the rat.
abstract: Normal projection development from the medial superior olive (MSO) to the inferior colliculus (IC) was examined by injecting Fluoro-Gold (FG), a retrograde tracer, into the IC unilaterally at postnatal days 0 (P0), P3, P7 and maturity. The rats were killed 1 day after FG injection. At all ages, labeled neurons in the MSO appeared on the ipsilateral side only, as in adult controls. The total number of MSO neurons counted in Nissl-stained sections was constant throughout the postnatal periods. The labeled frequency index of MSO neurons was increased stepwise (from 35% to 90%) with increasing postnatal stages (from P0 to adulthood), suggesting differential growth of early- and late-developing axons.
authors.affiliation: Department of Anatomy, School of Medicine, Kanazawa University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Okoyama
authors.forename: T
authors.initials: T
authors.lastname: Moriizumi
authors.forename: Y
authors.initials: Y
authors.lastname: Kitao
authors.forename: J
authors.initials: J
authors.lastname: Kawano
authors.forename: M
authors.initials: M
authors.lastname: Kudo
mesh_terms: D000367:Age Factors; D000818:Animals; D001369:Axons; D005260:Female; D005456:Fluorescent Dyes; D007245:Inferior Colliculi / Q000033:anatomy & histology* / Q000166:cytology / Q000254:growth & development; D008297:Male; D008856:Microscopy, Fluorescence; D009474:Neurons / Q000166:cytology; D009847:Olivary Nucleus / Q000033:anatomy & histology* / Q000166:cytology / Q000254:growth & development; D051381:Rats; D017207:Rats, Sprague-Dawley; D013266:Stilbamidines
chemical_list: C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D005456:Fluorescent Dyes; D013266:Stilbamidines