Sequence analysis of the 5.34-kb 5' flanking region of the human rhodopsin-encoding gene.
In order to define elements which may be involved in regulating human rhodopsin expression, we have isolated and sequenced a clone containing 5.34 kb of the 5'-upstream region of the human rhodopsin-encoding gene. The 5.34-kb human segment contains multiple potential transcription factor-binding sites and a subfamily of Alu repeats. The same subfamily of Alu repeats is found 5.8 kb upstream from the human red/green visual pigment-encoding gene.
Bennett
J
J
Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, School of Medicine, Philadelphia 19104-6069, USA.
Sun
D
D
Karikó
K
K
D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D006224:Cricetinae; D005796:Genes; D006801:Humans; D008969:Molecular Sequence Data; D012045:Regulatory Sequences, Nucleic Acid; D012091:Repetitive Sequences, Nucleic Acid; D012243:Rhodopsin / Q000235:genetics*; D014157:Transcription Factors / Q000378:metabolism
D014157:Transcription Factors; D012243:Rhodopsin