Second primary malignancies of the head and neck in children.
Second malignant neoplasms are not uncommon in children, especially following multimodality therapy. The incidence of second cancers may approach 12% at 20 years following the initial cancer. Diligent surveillance is mandatory over a patient's lifetime to minimize morbidity and mortality from second malignant neoplasms.
Myer
C M
CM
Department of Pediatric Otolaryngology, Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.
D000293:Adolescent; D018277:Carcinoma, Mucoepidermoid / Q000473:pathology; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology*; D009447:Neuroblastoma / Q000628:therapy; D012516:Osteosarcoma / Q000473:pathology; D010307:Parotid Neoplasms / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D012888:Skull Neoplasms / Q000473:pathology