Nonideality of water-hexafluoropropanol mixtures as studied by X-ray small angle scattering.
Strong temperature dependent low angle X-ray scattering by trifluoroethanol- and hexafluoro-2-propanol-water mixtures was observed in conditions commonly used in NMR work on peptides. At least two types of molecular effects may contribute to the observed scattering: formation of clathrate hydrate-like aggregates of alcohol with water as have been proposed for the similar system tert-butanol-water (Iwasaki, K. and Fujiyama, T. (1976) J. Phys. Chem. 81, 1908-1912) and a further heterogeneity of the solution resulting from immiscibility of the two components.
Kuprin
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S
Medical Nobel Institute for Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Gräslund
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A
Ehrenberg
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A
Koch
M H
MH
D000433:1-Propanol / Q000737:chemistry; D010455:Peptides / Q000737:chemistry; D020005:Propanols; D012542:Scattering, Radiation; D014867:Water / Q000737:chemistry*; D014965:X-Rays; D006845:Hydrocarbons, Fluorinated
D000433:1-Propanol; D010455:Peptides; D020005:Propanols; D014867:Water; C001337:hexafluoroisopropanol; D006845:Hydrocarbons, Fluorinated