title: Use of micellar electrokinetic capillary chromatography in the study of in vitro metabolism of phenol by human liver microsomes.
abstract: Micellar electrokinetic capillary chromatography (MECC) is used for analysis of microsome incubation samples. Phenol, a neutral analyte, is separated from interferences. The separation is achieved without sample clean-up. MECC is shown to be advantageous for situations where rapid sampling with minimum handling is desired.
authors.affiliation: Department of Chemistry, University of Kansas, Lawrence 66045, USA.
authors.forename: M I
authors.initials: MI
authors.lastname: Davies
authors.forename: C E
authors.initials: CE
authors.lastname: Lunte
authors.forename: M R
authors.initials: MR
authors.lastname: Smyth
mesh_terms: D002138:Calibration; D002845:Chromatography / Q000379:methods; D004563:Electrochemistry / Q000379:methods; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006873:Hydroquinones / Q000032:analysis; D008823:Micelles; D008862:Microsomes, Liver / Q000378:metabolism*; D010084:Oxidation-Reduction; D019800:Phenol; D010636:Phenols / Q000378:metabolism*; D012015:Reference Standards
chemical_list: D006873:Hydroquinones; D008823:Micelles; D010636:Phenols; D019800:Phenol; C031927:hydroquinone