title: A case of ovarian carcinoma with production of granulocyte colony-stimulating factor.
abstract: A 60-year-old female with ovarian carcinoma showed marked leucocytosis. After exploratory laparotomy she had received carboplatin-based chemotherapy, but she died of respiratory failure. In this case the immunohistochemical examination of the tumour cells showed partial-positive staining for anti-G-CSF monoclonal antibody in addition to the elevation of the serum G-CSF concentration. This case is the first report of an ovarian carcinoma producing G-CSF.
authors.affiliation: Department of Obstetrics and Gynaecology, Obihiro Kousei Hospital, Hokkaido, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Sudo
authors.forename: H
authors.initials: H
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Kikuchi
authors.forename: A
authors.initials: A
authors.lastname: Sumie
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: N
authors.initials: N
authors.lastname: Tumura
authors.forename: I
authors.initials: I
authors.lastname: Kawaguchi
authors.forename: S
authors.initials: S
authors.lastname: Fujimoto
authors.forename: A
authors.initials: A
authors.lastname: Kato
authors.forename: J
authors.initials: J
authors.lastname: Yamaguchi
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism*; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007964:Leukocytosis / Q000378:metabolism; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism*
chemical_list: D016179:Granulocyte Colony-Stimulating Factor