title: Circulatory assist techniques after cardiomyoplasty. Determinants for clinical outcome and later consequences.
abstract: Cardiomyoplasty, in spite of recent improvements, remains a high risk operation. The early postoperative period is sometimes very critical, even for patients selected from preoperative New York Heart Association functional class IV. During the surgical period, poor hemodynamics may be responsible for early death, as well as influence latissimus dorsi muscle long-term viability. Circulatory assist, including pharmacologic support with enoximone, intraaortic balloon counterpulsation (IABP), and ventricular assist devices (VAD), may be needed. From February, 1993 to September, 1994, 14 clinical dynamic cardiomyoplasty procedures were performed using the Medtronic (Minneapolis, MN) system at Hôpital La Timone, Marseille, France. Eight patients suffered from early and severe postoperative heart failure. Enoximone was used in three patients and IABP in five patients. Two days after cardiomyoplasty, one of the IABP patients required an implantable left VAD (Thermocardio Systems, Woburn, MA) as a bridge to cardiac transplantation. Overall hospital mortality was 7%. The authors studied the preoperative clinical data and surgical techniques to find specific risk factors that could have influenced postoperative events. Another aim of this study was to evaluate long-term benefits in these particular patients. Results showed that cardiomyoplasty patients may require complex means to overcome postoperative hemodynamic failure, but without necessarily poor long-term results. This should be an important step in improving future patient selection.
authors.affiliation: Department of Cardiac Surgery, Hôpital de la Timone, Marseille, France.
authors.forename: T G
authors.initials: TG
authors.lastname: Mesana
authors.forename: S
authors.initials: S
authors.lastname: Bauer
authors.forename: T
authors.initials: T
authors.lastname: Caus
authors.forename: C
authors.initials: C
authors.lastname: Pomane
authors.forename: A
authors.initials: A
authors.lastname: Mouly
authors.forename: J R
authors.initials: JR
authors.lastname: Montiès
mesh_terms: D000328:Adult; D000368:Aged; D001243:Assisted Circulation / Q000009:adverse effects* / Q000379:methods*; D018421:Cardiomyoplasty / Q000009:adverse effects* / Q000379:methods*; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011183:Postoperative Complications / Q000209:etiology; D011379:Prognosis; D012307:Risk Factors; D013997:Time Factors; D016277:Ventricular Function, Left