title: Huntington's disease. Their loss is our gain?
abstract: 'Knockout' mice have been developed that lack the Huntington's disease gene, in an effort to gain insight into the disorder and into the pathophysiological effects of tri-nucleotide repeat expansion.
authors.affiliation: Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA.
authors.forename: W
authors.initials: W
authors.lastname: Feero
authors.forename: E P
authors.initials: EP
authors.lastname: Hoffman
mesh_terms: D000818:Animals; D006801:Humans; D006816:Huntington Disease / Q000235:genetics* / Q000503:physiopathology; D051379:Mice; D018345:Mice, Knockout; D018911:Trinucleotide Repeats