title: Presentation of an acquired factor VIII inhibitor with a muscular haematoma mimicking a deep venous thrombosis in a patient with breast cancer.
abstract: Acquired haemophilia is a rare disorder that it is associated with several diseases. Patients may present with spontaneous haematomas in different places which can sometimes be fatal. We present a 69-year-old woman with breast carcinoma who developed a factor VIII inhibitor. The initial haemorrhagic event was a spontaneous deep muscular haematoma in the right leg mimicking a deep venous thrombosis. She was successfully treated with prednisone.
authors.affiliation: Haematology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: López
authors.forename: J
authors.initials: J
authors.lastname: Mateo
authors.forename: J
authors.initials: J
authors.lastname: Cruz
authors.forename: A
authors.initials: A
authors.lastname: López
authors.forename: T
authors.initials: T
authors.lastname: Urrutia
authors.forename: J
authors.initials: J
authors.lastname: Fontcuberta
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D001943:Breast Neoplasms / Q000150:complications; D003937:Diagnosis, Differential; D005169:Factor VIII / Q000037:antagonists & inhibitors*; D005260:Female; D006406:Hematoma / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D009135:Muscular Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D011241:Prednisone / Q000627:therapeutic use; D013924:Thrombophlebitis
chemical_list: D001323:Autoantibodies; D005169:Factor VIII; D011241:Prednisone