title: Ewing's sarcoma of bone: oncologic and functional results.
abstract: This paper describes 29 patients with Ewing's sarcoma of bone treated between 1975 and 1990 at the University of Nijmegen Hospital, Nijmegen, The Netherlands. Osteomyelitis was the primary diagnosis in 24%. Treatment consisted of chemotherapy in combination with surgery and/or radiotherapy. Nine patients received radiotherapy only; five of them died of disease. Five patients underwent an intralesional excision; four of them died of disease. Twelve patients underwent a wide excision; there is no evidence of disease in any of them. Three patients underwent a radical disarticulation; all died of disease. The disease-free survival at 1.5 years was 66%. This figure at 5 years was 55%. After wide excision and reconstruction in tumors of expendable, femoral or radial bones good functional results were obtained in all cases.
authors.affiliation: Department of Orthopaedics, University Hospital of St. Radboud, University of Nijmegen, The Netherlands.
authors.forename: A J
authors.initials: AJ
authors.lastname: Renard
authors.forename: R P
authors.initials: RP
authors.lastname: Veth
authors.forename: M
authors.initials: M
authors.lastname: Pruszczynksi
authors.forename: J
authors.initials: J
authors.lastname: Hoogenhout
authors.forename: J
authors.initials: J
authors.lastname: Bökkerink
authors.forename: F J
authors.initials: FJ
authors.lastname: van der Staak
authors.forename: T
authors.initials: T
authors.lastname: Wobbes
authors.forename: J A
authors.initials: JA
authors.lastname: Lemmens
authors.forename: R
authors.initials: R
authors.lastname: van Hoesel
authors.forename: J R
authors.initials: JR
authors.lastname: van Horn
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects; D012512:Sarcoma, Ewing / Q000503:physiopathology / Q000628:therapy*