[Phosphoinositide response and changes in the supraoptic-neurohypophyseal system in individual resistance of rats to hypoxia].
The dynamics of phosphatidyl inositol, phosphatidyl inositol-4-phosphate and phosphatidyl inositol-4.5-diphosphate was studied in brain and liver tissues of rats with hypoxia developed as a result of treatment in the altitude chamber at 6,000 m, daily 6 hrs, on day 30. The content of phosphatidyl inositol-4-phosphate and--4.5-diphosphate was increased on days 3 and 30 altitude post-training. This hypoxia caused impairments in brain circulation as well as led to increase in the hypophysis mass in lowly resistant rats within early periods of treatment and in highly resistant animals on day 30.
Vishnevskiĭ
A A
AA
Iangalycheva
E Ia
EIa
Iakovlev
V M
VM
D000818:Animals; D000860:Hypoxia / Q000378:metabolism / Q000503:physiopathology*; D008099:Liver / Q000378:metabolism; D008297:Male; D010716:Phosphatidylinositols / Q000378:metabolism*; D010904:Pituitary Gland, Posterior / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013495:Supraoptic Nucleus / Q000378:metabolism*
D010716:Phosphatidylinositols
Fosfoinozitidnyĭ otvet i izmeneniia v supraoptiko-neĭrogipofizarnoĭ sisteme pri individual'noĭ rezistentnosti krys k gipoksii.