Effects of postnatal stimulation on the passive avoidance behaviour of young rats.
We examined the effects of stimulation on either postnatal days 1-7 or 21-27 on passive avoidance reaction (PAR) of young rats. Animals received tactile or visual stimulation for 10 min each day, and were trained on postnatal day 28 in a step-through apparatus using a footshock of 0.75 mA for 2 s. Retention was tested on five consecutive days beginning on day 29. Memory retention was measured for each rat 24, 48, 72, 96 and 120 h after the acquisition trial. Step-through latencies to enter the dark compartment, time spent in the illuminated compartment and number of crossings of the light beam were recorded up to 200 s. Rats that received tactile or visual stimulation during the 4th postnatal week displayed significantly lower PAR latencies, a shorter stay in the illuminated compartment and a higher number of crossings of the light beam compared to rats treated during the 1st postnatal week. The untreated control group showed a rapid decline of PAR latencies. All experimental groups remained in the illuminated compartment longer and showed PAR latencies well above those of the control group. The differences became more pronounced when visual stimulation in the first postnatal week was used. The number of crossings of the light beam was significantly reduced by the treatment, with the exception of the experimental group stimulated visually in the 4th week. The behavioural changes induced by tactile or visual stimulation have a long-lasting effect in coping with a stressful task.
Gschanes
A
A
Centre of Animal Biology, Medical School Graz, Graz University, Austria.
Eggenreich
U
U
Windisch
M
M
Crailsheim
K
K
D000818:Animals; D000831:Animals, Newborn; D001143:Arousal / Q000502:physiology*; D001362:Avoidance Learning / Q000502:physiology*; D001921:Brain / Q000254:growth & development*; D003118:Color Perception / Q000502:physiology; D005260:Female; D006234:Handling, Psychological; D008297:Male; D011939:Mental Recall / Q000502:physiology; D010775:Photic Stimulation; D011247:Pregnancy; D051381:Rats; D017207:Rats, Sprague-Dawley; D012153:Retention, Psychology / Q000502:physiology*; D012931:Social Environment; D014110:Touch / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*