title: [Therapeutic management and survival of gastric adenocarcinoma in the province of Finistère between 1984 and 1989].
abstract: OBJECTIVE
  The aim of this study was to analyze the evolution of treatment regimens and survival rates of stomach adenocarcinoma recorded in the Finistère cancer registry from 1984 to 1989.
  
  
  METHODS
  In a population of 838,627 inhabitants, 1,280 patients with a gastric cancer were registered; 1,164 patients (693 males and 471 females) had an adenocarcinoma. Survival rates were estimated by the actuarial method, and compared using the logrank test and the Cox model.
  
  
  RESULTS
  Surgical resection was the main treatment for 661 patients (57%). The frequency of curative resection increased from 25% between 1984 and 1986 to 35% after 1986. Among the other patients, 39 (3%) were treated by chemotherapy and/or radiotherapy, and 53 patients (4%) by endoscopy alone; 253 patients had only symptomatic treatment. The survival rates of all patients were 43% at 1 year and 20% at 5 years. The median survival was 9.2 +/- 0.6 months. In patients with cancer managed surgically, the factors associated with a better prognosis were young age, long duration of symptoms before diagnosis, ulcerated macroscopic aspect, limited tumour extension and curative surgical resection. In other patients, 2 factors were associated a with better prognosis: the absence of metastases and an endoscopic palliative treatment.
  
  
  CONCLUSIONS
  Surgical resection is the main treatment of gastric adenocarcinoma. Although the frequency of surgery increased, the prognosis of gastric adenocarcinoma did not improve within this 6-year period.
authors.affiliation: Service d'Hépato-Gastroentérologie, CH de Cornouaille, Quimper.
authors.forename: M
authors.initials: M
authors.lastname: Le Page
authors.forename: J M
authors.initials: JM
authors.lastname: Cauvin
authors.forename: G
authors.initials: G
authors.lastname: Le Dréau
authors.forename: J B
authors.initials: JB
authors.lastname: Nousbaum
authors.forename: L
authors.initials: L
authors.lastname: Enard
authors.forename: A
authors.initials: A
authors.lastname: Gourlaouen
authors.forename: M
authors.initials: M
authors.lastname: Robaszkiewicz
authors.forename: H
authors.initials: H
authors.lastname: Gouérou
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality* / Q000601:surgery / Q000628:therapy; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013274:Stomach Neoplasms / Q000401:mortality* / Q000601:surgery / Q000628:therapy
vernacular_title: Prise en charge thérapeutique et survie de l'adénocarcinome gastrique dans le département du Finistère entre 1984 et 1989.