Analysis of changes in coagulation factors after postoperative blood loss in burn and non-burn patients.
A prospective study of the postoperative kinetics of coagulation factors was undertaken in 23 burn patients and in six non-burn patients. All procedures resulted in a large volume blood loss. Fibrinogen, platelets and factors V, VIII and IX were measured serially. Burn patients returned all parameters to preoperative levels by 48 h postoperation, while non-burn patients showed a slower rate of return of platelets and factor V. This study suggests that burn patients may safely undergo re-operation at 48 h intervals for successive wound debridements if clinically necessary.
Chang
P
P
Department of Surgery, University of Iowa College of Medicine, Iowa City, USA.
Murray
D J
DJ
Olson
J D
JD
Pennell
B J
BJ
Lewis
R W
RW
Kealey
G P
GP
D000293:Adolescent; D000328:Adult; D000368:Aged; D001779:Blood Coagulation Factors / Q000378:metabolism*; D002056:Burns / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008875:Middle Aged; D010976:Platelet Count; D019106:Postoperative Hemorrhage / Q000097:blood* / Q000601:surgery; D011446:Prospective Studies; D012086:Reoperation
D001779:Blood Coagulation Factors