27-O-demethylrapamycin, an immunosuppressant compound produced by a new strain of Streptomyces hygroscopicus.
Box
S J
SJ
SmithKline Beecham Pharmaceuticals, Betchworth, Surrey, UK.
Shelley
P R
PR
Tyler
J W
JW
Verrall
M S
MS
Warr
S R
SR
Badger
A M
AM
Levy
M A
MA
Banks
R M
RM
D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003208:Concanavalin A / Q000494:pharmacology; D004268:DNA-Binding Proteins / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000378:metabolism; D007166:Immunosuppressive Agents; D008070:Lipopolysaccharides / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015394:Molecular Structure; D011090:Polyenes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D011714:Pyrans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D011994:Recombinant Proteins / Q000378:metabolism; D020123:Sirolimus; D013154:Spleen / Q000166:cytology; D013302:Streptomyces / Q000378:metabolism*; D022021:Tacrolimus Binding Proteins
C097851:27-O-demethylrapamycin; D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D006360:Heat-Shock Proteins; D007166:Immunosuppressive Agents; D008070:Lipopolysaccharides; D011090:Polyenes; D011714:Pyrans; D011994:Recombinant Proteins; D003208:Concanavalin A; D022021:Tacrolimus Binding Proteins; D020123:Sirolimus