Effects of observed correlation structure among tumor types on experimentwise false positive rate in animal carcinogenicity studies.
Probabilities P1, P2, ..., Pn of n events E1, E2, ..., En can impose constraints on the probability of a further event E. deFinetti's fundamental theorem of probability characterizes the interval of coherent probability of E. Lad, Dickey, and Rahman (5) extended deFinetti's theorem in a few directions. In this work we will show some applications of these results to the calculation of experimentwise false positive error rate in multiple hypotheses testing procedure.
Rahman
M A
MA
Division of Biometrics, Food and Drug Administration, Rockville, Maryland 20857, USA.
D000818:Animals; D015197:Carcinogenicity Tests / Q000706:statistics & numerical data*; D005189:False Positive Reactions; D008433:Mathematics; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology; D011338:Probability Theory