title: [Hyaluronidase as a therapeutic alternative in perforated tympanum].
abstract: There are many causes of tympanic perforation but usually only one treatment, surgical. However, many patients cannot or will not undergo surgery. In such cases, treatment with sodium hyaluronidate may be satisfactory. In our group of 20 patients with 21 tympanic perforations who underwent this treatment, 15 evolved favorably. The drawbacks and patient selection are discussed.
authors.affiliation: Servicio de ORL, Hospital Universitario La Fe, Valencia.
authors.forename: M D
authors.initials: MD
authors.lastname: Sánchez-Alcón
authors.forename: A
authors.initials: A
authors.lastname: Alamar
authors.forename: H
authors.initials: H
authors.lastname: Pérez
authors.forename: P
authors.initials: P
authors.lastname: Sancho-Miñana
authors.forename: S
authors.initials: S
authors.lastname: Sánchez
authors.forename: C
authors.initials: C
authors.lastname: Morera
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006026:Glycoside Hydrolases / Q000627:therapeutic use*; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D018058:Tympanic Membrane Perforation / Q000188:drug therapy*
chemical_list: D006026:Glycoside Hydrolases; D006821:Hyaluronoglucosaminidase
vernacular_title: La hialuronidasa como alternativa al tratamiento de las perforaciones timpánicas.