title: Preoperative serum intercellular adhesion molecule-1 (ICAM-1) and E-selectin (endothelial cell leukocyte adhesion molecule, ELAM-1) in patients with epithelial ovarian cancer.
abstract: The serum levels of intercellular adhesion molecule-1 (ICAM-1) and E-Selectin (endothelial cell leukocyte adhesion molecule, ELAM-1) were retrospectively measured in serum samples drawn at diagnosis from 66 patients with epithelial ovarian cancer and 128 patients with benign ovarian masses. The preoperative serum ICAM-1 levels were higher in the former group (p < 0.0001), while serum E-Selectin concentrations were similar in the two groups (p = NS). Among patients with epithelial ovarian cancer, neither serum ICAM-1 nor E-selectin levels correlated with FIGO stage and with histologic type. The serum assay of ICAM-1 and E-Selectin seems to have limited value in the management of patients with epithelial ovarian cancer.
authors.affiliation: Istituto di Medicina Nucleare, Università di Pisa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Ferdeghini
authors.forename: A
authors.initials: A
authors.lastname: Gadducci
authors.forename: C
authors.initials: C
authors.lastname: Prontera
authors.forename: C
authors.initials: C
authors.lastname: Annicchiarico
authors.forename: O
authors.initials: O
authors.lastname: Gagetti
authors.forename: M
authors.initials: M
authors.lastname: Bianchi
authors.forename: V
authors.initials: V
authors.lastname: Facchini
authors.forename: A R
authors.initials: AR
authors.lastname: Genazzani
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019040:E-Selectin / Q000097:blood*; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000097:blood*; D010051:Ovarian Neoplasms / Q000097:blood*; D012189:Retrospective Studies
chemical_list: D019040:E-Selectin; D018799:Intercellular Adhesion Molecule-1