Bone mineral status in preterm-born children: assessment by dual-energy X-ray absorptiometry.
To elucidate the long-term consequences of osteopenia of prematurity, lumbar spinal bone mass was measured in 21 preterm-born children aged 3-4 years by dual-energy X-ray absorptiometry. Their mineral intake remained low during early life, and all 11 infants previously studied were osteopenic at term postconception. At the age of 3-4 years, however, all 21 children were found to have normal bone mineral content and density with slightly elevated serum osteocalcin levels. Our results show that in preterm-born children spontaneous resolution of lumbar spinal osteopenia occurs during early childhood.
Hori
C
C
Department of Pediatrics, Fukui Medical School, Japan.
Tsukahara
H
H
Fujii
Y
Y
Kawamitsu
T
T
Konishi
Y
Y
Yamamoto
K
K
Ishii
Y
Y
Sudo
M
M
D015502:Absorptiometry, Photon / Q000592:standards*; D001835:Body Weight / Q000502:physiology; D015519:Bone Density / Q000502:physiology*; D001851:Bone Diseases, Metabolic / Q000097:blood / Q000503:physiopathology; D002118:Calcium / Q000097:blood; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D007235:Infant, Premature, Diseases / Q000097:blood / Q000503:physiopathology; D008159:Lumbar Vertebrae / Q000502:physiology; D008297:Male; D015675:Osteocalcin / Q000097:blood; D012075:Remission, Spontaneous
D015675:Osteocalcin; D002118:Calcium