title: Leydig cell tumour in a man with human immunodeficiency virus.
abstract: We report a case of Leydig-cell testicular tumour in a 32-year-old intravenous drug abuser bearing HIV-infection and pulmonary tuberculosis. The testicular mass was initially interpreted as genital tuberculosis and the diagnosis was made by aspiration cytology. Radical orchiectomy was performed and pathology revealed a Leydig-cell tumour. Gynecomastia was found as a possible sign of endocrine activity. Although testicular malignancies in men with human immunodeficiency virus are increasingly reported, this is the first case of Leydig-cell neoplasia associated to HIV-infection.
authors.affiliation: Department of Urology, Hospital Principe de Asturias, Universidad de Alcalá de Henares, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Sanchez-Chapado
authors.forename: J C
authors.initials: JC
authors.lastname: Angulo
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007984:Leydig Cell Tumor / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D008297:Male; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D014376:Tuberculosis / Q000150:complications