title: Pyrroloquinoline quinone, a chemotactic attractant for Escherichia coli.
abstract: Escherichia coli is attracted by pyrroloquinoline quinone (PQQ), and chemotaxis toward glucose is enhanced by the presence of PQQ. A ptsI mutant showed no chemotactic response to either glucose or PQQ alone but did show a chemotactic response to a mixture of glucose and PQQ. A strain lacking the methylated chemotaxis receptor protein Tar showed no response to PQQ.
authors.affiliation: Department of Microbiology, E.C. Slater Institute, University of Amsterdam, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: de Jonge
authors.forename: M J
authors.initials: MJ
authors.lastname: Teixeira de Mattos
authors.forename: J B
authors.initials: JB
authors.lastname: Stock
authors.forename: O M
authors.initials: OM
authors.lastname: Neijssel
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D002628:Chemoreceptor Cells; D002630:Chemotactic Factors / Q000494:pharmacology*; D002633:Chemotaxis / Q000502:physiology*; D003067:Coenzymes / Q000494:pharmacology; D004347:Drug Interactions; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology*; D029968:Escherichia coli Proteins; D005947:Glucose / Q000494:pharmacology; D005948:Glucose Dehydrogenases / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics; D009154:Mutation; D045542:PQQ Cofactor; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000235:genetics; D017852:Phosphotransferases (Nitrogenous Group Acceptor) / Q000235:genetics; D015363:Quinolones / Q000494:pharmacology*; D011956:Receptors, Cell Surface; D015398:Signal Transduction
chemical_list: D001426:Bacterial Proteins; D002630:Chemotactic Factors; D003067:Coenzymes; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D015363:Quinolones; D011956:Receptors, Cell Surface; C057331:Tar protein, E coli; D045542:PQQ Cofactor; D005948:Glucose Dehydrogenases; C033955:glucose dehydrogenase (pyrroloquinoline-quinone); D010731:Phosphoenolpyruvate Sugar Phosphotransferase System; D017852:Phosphotransferases (Nitrogenous Group Acceptor); C022360:phosphoenolpyruvate-protein phosphotransferase; D005947:Glucose