Pregnancy and birth after intracytoplasmic sperm injection with spermatozoa from a patient with tail stump syndrome.
Tail stump syndrome, which may be associated with primary ciliary dyskinesia, is also associated with morphological defects of the flagellum resulting in severe asthenozoospermia. Until recently, these morphological anomalies caused definite male infertility. Today, however, new methods such as micromanipulation techniques provide a rational therapy for this patient group. A pregnancy followed by living offspring was achieved following the intracytoplasmic injection of immotile spermatozoa from a patient with tail stump syndrome.
Stalf
T
T
Department of Dermatology and Andrology, Justus Liebig University, Gìessen, Germany.
Sánchez
R
R
Köhn
F M
FM
Schalles
U
U
Kleinstein
J
J
Hinz
V
V
Tielsch
J
J
Khanaga
O
O
Turley
H
H
Gips
H
H
D000328:Adult; D003593:Cytoplasm; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000473:pathology; D008297:Male; D008845:Microinjections; D011247:Pregnancy; D011256:Pregnancy Outcome; D013081:Sperm Motility / Q000502:physiology; D013082:Sperm Tail / Q000473:pathology*; D013094:Spermatozoa; D013577:Syndrome; D016896:Treatment Outcome