Compressive and bone-bonding strength of hydroxyapatite thermal decomposition product implanted in the femur of rabbit as a bioactive ceramic bone cement.
Hydroxyapatite thermal decomposition product (HATDP) after mixing with water was injected into the femur of rabbits, and its biocompatibility, compressive strength and bone-bonding strength were investigated. The compressive strength of a block of HATDP was 56.0 MPa 4 weeks after injection, which was about 60% of that of poly(methyl methacrylate) (PMMA) cement. The bone-bonding strength was 8.2 MPa 4 weeks after injection, which was significantly higher than that of PMMA cement. HATDP seems to be useful as a cement material because of its good bone-bonding property and relatively high mechanical strength.
Takahashi
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Department of Orthopaedic Surgery, Yokohama City University School of Medicine, Kanagawa, Japan.
Koshino
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D000042:Absorption; D000818:Animals; D001672:Biocompatible Materials / Q000592:standards; D001696:Biomechanical Phenomena; D001843:Bone Cements / Q000592:standards*; D002516:Ceramics; D004396:Coloring Agents; D005269:Femur / Q000000981:diagnostic imaging / Q000502:physiology; D006882:Hydroxyapatites; D008768:Methylmethacrylates; D019736:Prostheses and Implants / Q000592:standards*; D011817:Rabbits; D011859:Radiography; D012015:Reference Standards; D014048:Tolonium Chloride / Q000737:chemistry
D001672:Biocompatible Materials; D001843:Bone Cements; D004396:Coloring Agents; D006882:Hydroxyapatites; D008768:Methylmethacrylates; D014048:Tolonium Chloride