MMP-8 (neutrophil collagenase) mRNA and aggrecanase cleavage products are present in normal and osteoarthritic human articular cartilage.
Cole
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Department of Biochemistry, Rush Medical College at Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612, USA.
Kuettner
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D000328:Adult; D001483:Base Sequence; D002358:Cartilage, Articular / Q000737:chemistry* / Q000196:embryology; D002478:Cells, Cultured; D017364:Collagenases / Q000235:genetics* / Q000378:metabolism; D018076:DNA, Complementary / Q000032:analysis; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D017403:In Situ Hybridization; D066298:In Vitro Techniques; D020784:Matrix Metalloproteinase 8; D008969:Molecular Sequence Data; D009504:Neutrophils / Q000737:chemistry; D010003:Osteoarthritis / Q000378:metabolism*; D012333:RNA, Messenger / Q000032:analysis*; D012016:Reference Values; D012680:Sensitivity and Specificity
D018076:DNA, Complementary; D012333:RNA, Messenger; D010450:Endopeptidases; D017364:Collagenases; D020784:Matrix Metalloproteinase 8; C083641:aggrecanase