title: Appendiceal intussusception due to an appendiceal malignant polyp--an association in a patient with Peutz-Jeghers syndrome: report of a case.
abstract: A 40-year-old woman with Peutz-Jeghers syndrome and an appendiceal intussusception is reported. In this patient, the lead point was a large sessile, appendiceal polyp. The invaginated and inverted portion of the appendix resembled the long stalk of a pedunculated polyp on roentgenography and endoscopic examination. Histologically, the appendiceal polyp was a villous adenoma with mild to severe atypia and focal carcinoma in situ. In patients with Peutz-Jeghers syndrome, hamartomatous polyps and colorectal adenomatous polyps with highly malignant potential can coexist and must be managed appropriately. Therefore, when evaluating a polypoid or a pedunculated lesion in the cecal lumen, the possibility of an appendiceal intussusception should also be investigated.
authors.affiliation: Department of Surgery I, Oita Medical University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Miyahara
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: K
authors.initials: K
authors.lastname: Etoh
authors.forename: K
authors.initials: K
authors.lastname: Shimoda
authors.forename: S
authors.initials: S
authors.lastname: Kitano
authors.forename: M
authors.initials: M
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Yokoyama
mesh_terms: D018253:Adenoma, Villous / Q000473:pathology / Q000601:surgery*; D000328:Adult; D001062:Appendectomy; D001063:Appendiceal Neoplasms / Q000473:pathology / Q000601:surgery*; D001065:Appendix / Q000473:pathology; D002278:Carcinoma in Situ / Q000473:pathology / Q000601:surgery*; D002429:Cecal Diseases / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007417:Intestinal Polyps / Q000473:pathology / Q000601:surgery*; D007443:Intussusception / Q000473:pathology / Q000601:surgery*; D010580:Peutz-Jeghers Syndrome / Q000473:pathology / Q000601:surgery