[Flubiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic].
OBJECTIVE
We compared the efficacy of flurbiprofen (NSAID) versus dipirone + hyoscine N-butylbromide in the treatment of nephric colic.


METHODS
The study comprised 135 patients, aged 18 to 75 yrs, with intense nephric colic. The patients were observed 60 min after a single IM dose of 150 mg flurbiprofen (n = 67) or 2 gm dipirone + 20 mg hyoscine N-butylbromide.


RESULTS
Both treatment modalities were well-tolerated and afforded significant pain relief. Flurbiprofen, however, was faster-acting and superior to dipirone + hyoscine in the overall evaluation of good and excellent therapeutic response rates.


CONCLUSIONS
The results of the study show that IM flurbiprofen is a useful alternative to dipirone + hyoscine N-butylbromide in the treatment of nephric colic.
Mora Durban
M J
MJ
Servicio de Urología, Hospital de Móstoles, Madrid, España.
Extramiana Cameno
J
J
Arrizabalaga Moreno
M
M
Paniagua Andrés
P
P
Camp Herrero
J
J
Milla Santos
J
J
del Nogal Saez
F
F
Gimeno Albo
F
F
Moreno Carretero
E
E
Domínguez Granados
R
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002086:Butylscopolammonium Bromide / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D003085:Colic / Q000188:drug therapy*; D004177:Dipyrone / Q000627:therapeutic use*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D005480:Flurbiprofen / Q000627:therapeutic use*; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012601:Scopolamine / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002086:Butylscopolammonium Bromide; D005480:Flurbiprofen; D004177:Dipyrone; D012601:Scopolamine
Flubiprofeno vs dipirona asociada a hioscina: eficacia analgésica en el cólico nefrítico.