A new spontaneous allele at the pink-eyed dilution (p) locus discovered in Mus musculus castaneus.
Mutant mice characterized by a cream coat and pink eyes were spontaneously discovered among the descendants of Indonesian wild mice (Mus musculus castaneus). This mutant phenotype was controlled by a single autosomal recessive gene that was allelic to the pink-eyed dilution (p) gene. The mutant mouse phenotypically resembled the original p mouse which was the first mutant identified at this locus. Nevertheless, these two alleles differed in origin, a previous report suggesting that the original p allele was derived from Japanese wild mice (M. m. molossinus). Thus the symbol pcas (pink-eyed castaneus) was proposed for the present mutation allele.
Tsuji
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Laboratory of Animal Genetics, School of Agricultural Sciences, Nagoya University, Aichi, Japan.
Wakayama
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Ishikawa
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D000483:Alleles; D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D008040:Genetic Linkage; D005838:Genotype; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008817:Mice, Mutant Strains / Q000235:genetics*; D010641:Phenotype