Clinical analysis of steroid glaucoma.
OBJECTIVE
The authors accumulated 15 cases (26 eyes) of steroid glaucoma due to topical administration of dexamethasone or prednisolone.


METHODS
From 1970 to 1990, 26 eyes in 15 cases were observed (bilateral 11 cases, unilateral 4 cases) including 12 right eyes and 14 left eyes. 10 cases were male and 5 cases female with age ranging from 14 to 52 years averaging 28 years. 25 eyes had the manifestation of chronic open angle glaucoma in the clinical course, and 1 eye simulated an acute glaucoma attack.


RESULTS
All patients had taken antiglaucoma medication before coming to our hospital, but the IOP was over 6.7 kPa in 9 eyes. The C/D ratio was equal to or over 0.6 in 9 cases (16 eyes), and the values were inconsistent between both eyes in 55% of the patients. Treatment for glaucoma was immediate discontinuation of the steroids with antiglaucoma medication if necessary. Three eyes received filtering operations and 2 eyes had the removal of subconjunctival residual steroid. Normal IOP was restored in months up to a year.


CONCLUSIONS
Dexamethasone or prednisolone were the easiest to induce steroid glaucoma when the patients had long-term use of steroid eyedrops.
Kong
L
L
Department of Ophthalmology, First Teaching Hospital, Henan Medical University, Zhengzhou, China.
Zhang
C
C
Chen
M
M
Xue
G
G
D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D003233:Conjunctivitis, Allergic / Q000188:drug therapy; D003907:Dexamethasone / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D007500:Iritis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010862:Pilocarpine / Q000627:therapeutic use; D011239:Prednisolone / Q000009:adverse effects*; D013999:Timolol / Q000627:therapeutic use; D014794:Visual Fields
D000893:Anti-Inflammatory Agents; D010862:Pilocarpine; D003907:Dexamethasone; D013999:Timolol; D011239:Prednisolone