title: Left ventricular fibromuscular band is not a specific substrate for idiopathic left ventricular tachycardia.
abstract: BACKGROUND
  A fibromuscular band has been detected in patients with idiopathic left ventricular tachycardia, and this band has been suggested to be the anatomic substrate for the arrhythmia. Whether the fibromuscular band is a specific substrate for the tachycardia was systematically evaluated in a large group of consecutive patients with and without idiopathic left ventricular tachycardia.
  
  
  RESULTS
  Conventional transthoracic two-dimensional echocardiography and multiplane transesophageal echocardiography were performed in 18 patients with idiopathic left ventricular tachycardia that was responsive to calcium blockers (group 1, tachycardia patients) and 40 patients with paroxysmal supraventricular tachycardia (group 2, control patients). There were 17 men and 1 woman, with a mean age of 29 +/- 11 years, in group 1 patients, and 21 men and 19 women, with a mean age of 42 +/- 12 years, in group 2 patients. The QRS morphology during tachycardia in group 1 patients displayed a pattern of right bundle-branch block with superior axis in 15 patients, indeterminate axis in 2 patients, and inferior axis in 1 patient. Radiofrequency ablation successfully eliminated the tachycardia in all 18 patients; the successful ablation site was located at the inferior apical septum in 11 patients, at the midseptum in 6 patients, and at the anterior lateral wall in 1 patient. Transthoracic echocardiography detected the fibromuscular band in 11 of the 18 patients, whereas multiplane transesophageal echocardiography detected the band in 17 of 18 patients. The fibromuscular band extended from the interventricular septum to the apex of the left ventricle. In group 2 patients, transthoracic echocardiography detected the fibromuscular band in 22 and multiplane transesophageal echocardiography detected the band in 35 of the 40 patients. The presence of a fibromuscular band in these two groups of patients was not statistically different.
  
  
  CONCLUSIONS
  The presence of a left ventricular fibromuscular band is not a specific anatomic substrate for idiopathic left ventricular tachycardia.
authors.affiliation: Department of Medicine, Chang Gung Memorial Hospital, Chang Gung Medical College, Taipei, Taiwan.
authors.forename: F C
authors.initials: FC
authors.lastname: Lin
authors.forename: M S
authors.initials: MS
authors.lastname: Wen
authors.forename: C C
authors.initials: CC
authors.lastname: Wang
authors.forename: S J
authors.initials: SJ
authors.lastname: Yeh
authors.forename: D
authors.initials: D
authors.lastname: Wu
mesh_terms: D000328:Adult; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D017115:Catheter Ablation; D004452:Echocardiography; D017548:Echocardiography, Transesophageal; D005260:Female; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D008297:Male; D013617:Tachycardia, Supraventricular / Q000209:etiology; D017180:Tachycardia, Ventricular / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy
chemical_list: D002121:Calcium Channel Blockers