[Chronic hepatitis B infection and liver failure following kidney transplantation].
Chronic liver diseases, especially due to chronic hepatitis B virus infection, are among the leading causes of late mortality in renal transplant recipients. We report on 4 HBsAg-positive patients observed over a period of 8 years, who were free of symptomatic liver disease for 7-19 years after renal transplantation and died within a few days of acute hepatic failure. The cases presented document the prognostic relevance of chronic hepatitis B virus infection in renal transplant recipients and illustrate that an asymptomatic HBsAg carrier state can evolve within a very short time to fatal liver disease.
Christen
R
R
Medizinische Klinik, Kantonsspital Olten.
Blumberg
A
A
Pirovino
M
M
D000328:Adult; D000368:Aged; D002353:Carrier State; D006509:Hepatitis B / Q000150:complications* / Q000276:immunology; D006513:Hepatitis B e Antigens; D006521:Hepatitis, Chronic / Q000150:complications*; D006801:Humans; D016030:Kidney Transplantation; D017093:Liver Failure / Q000209:etiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology
D006513:Hepatitis B e Antigens
Chronische HBV-Infektion und Leberversagen nach Nierentransplantation.