title: Bioactivity of certain medicinal latexes used by the Ese'ejas.
abstract: Latexes from Croton erythrochilus, Ficus inspidia and Sapium marmieri used traditionally as medicinal by the Ese'ejas were analyzed for bioactivity. The assays run were: the brine shrimp toxicity microplate bioassay, the wheat rootlet growth inhibition and the DNA-methyl green bioassay. The three latexes showed cytotoxicity to the brine shrimp and concentration-related growth inhibition. No interaction with the DNA-methyl green complex was observed with any of the three latex samples. The field bioassays described has demonstrated to be useful for supporting ethnobotanical information.
authors.affiliation: Cátedra de Biotecnología y Microbiología Industrial, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín, Argentina.
authors.forename: E
authors.initials: E
authors.lastname: Mongelli
authors.forename: C
authors.initials: C
authors.lastname: Desmarchelier
authors.forename: A
authors.initials: A
authors.lastname: Giulietti
authors.forename: J
authors.initials: J
authors.lastname: Coussio
authors.forename: G
authors.initials: G
authors.lastname: Ciccia
mesh_terms: D000818:Animals; D001118:Argentina; D001156:Artemia / Q000187:drug effects; D001681:Biological Assay; D003124:Colorimetry; D004247:DNA / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D007840:Latex / Q000633:toxicity*; D007928:Lethal Dose 50; D008739:Methyl Green / Q000737:chemistry; D018517:Plant Roots / Q000187:drug effects / Q000254:growth & development; D010946:Plants, Medicinal; D014908:Triticum / Q000187:drug effects
chemical_list: D007840:Latex; D008739:Methyl Green; D004247:DNA