Natural history of untreated cytomegalovirus retinitis.
Cytomegalovirus infection is common in patients with AIDS, and often causes retinitis. Treatment is rarely curative, but the progression of retinitis is delayed. The untreated course of cytomegalovirus retinitis in AIDS is unknown. We report a 35-year-old man with retinitis who refused treatment. Retinitis resulted in blindness within 6 months. Measurement of cytomegalovirus genomes showed an increasing viral load in blood and urine.
Bowen
E F
EF
Department of Virology, Royal Free Hospital School of Medicine, Hampstead, London, UK.
Wilson
P
P
Atkins
M
M
Madge
S
S
Griffiths
P D
PD
Johnson
M A
MA
Emery
V C
VC
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D001766:Blindness / Q000209:etiology; D001769:Blood / Q000821:virology; D003587:Cytomegalovirus / Q000235:genetics; D017726:Cytomegalovirus Retinitis / Q000150:complications* / Q000821:virology; D016679:Genome, Viral; D006801:Humans; D008297:Male; D014556:Urine / Q000821:virology