Thrombocytopenia in patients infected with human immunodeficiency virus: treatment update.
Thrombocytopenia that is associated with infection due to human immunodeficiency virus (HIV) is an important and common hematologic abnormality. Although this condition is often asymptomatic, it may manifest clinically as a spectrum of bleeding problems including petechiae, ecchymoses, epistaxis, or menorrhagia or as hemorrhage of the gingivae, gastrointestinal tract, or CNS. Thrombocytopenia may be present in patients at any stage of immunodeficiency, and spontaneous remission can occur. We review the natural history of HIV-related thrombocytopenia and discuss treatment options.
Glatt
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Department of Medicine, Catholic Medical Center of Brooklyn and Queens, Jamaica, New York 11432, USA.
Anand
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D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006801:Humans; D013921:Thrombocytopenia / Q000209:etiology* / Q000628:therapy*