title: [Disseminated cutaneous neurilemmomatosis].
abstract: BACKGROUND
  Neurilemmomatosis is a rare, non-inherited disease which has several features similar to type I neurofibromatosis.
  
  
  METHODS
  A 30-year-old man had more than 300 cutaneomucosal tumours. Most were sessile and of firm consistency on normal coloured skin. Histology reported masses of fusiform dermal cells S100 protein (+), NSE (-), actin (-). The cells had a polygonal ultrastructure with fine ramifications. Neurilemmomatosis (schwannomatosis) was diagnosed. No neurological or systemic disorder could be detected. The most bothersome tumors were destroyed.
  
  
  CONCLUSIONS
  This is a typical anatomoclinical presentation of cutaneous neurilemmomatosis. This exceptional state raises the problem of differential diagnosis and nosological distinction from von Recklinhausen's disease. A characteristic feature in this case was the total absence of any malformation or associated tumour, notably neurological tumours. To our knowledge, this is the only documented case of disseminated neurilemmomatosis strictly limited to the skin.
authors.affiliation: Service de Dermatologie, Hôpital de l'Antiquaille, Lyon.
authors.forename: L
authors.initials: L
authors.lastname: Thomas
authors.forename: J
authors.initials: J
authors.lastname: Chaudier
authors.forename: A
authors.initials: A
authors.lastname: Fiere
authors.forename: G
authors.initials: G
authors.lastname: Choquet
authors.forename: B
authors.initials: B
authors.lastname: Balme
authors.forename: D
authors.initials: D
authors.lastname: Barrut
authors.forename: J
authors.initials: J
authors.lastname: Kanitakis
authors.forename: G
authors.initials: G
authors.lastname: Moulin
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009442:Neurilemmoma / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D009456:Neurofibromatosis 1 / Q000175:diagnosis; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure
vernacular_title: Neurilemmomatose cutanée disséminée.