title: [Flubiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic].
abstract: OBJECTIVE
  We compared the efficacy of flurbiprofen (NSAID) versus dipirone + hyoscine N-butylbromide in the treatment of nephric colic.
  
  
  METHODS
  The study comprised 135 patients, aged 18 to 75 yrs, with intense nephric colic. The patients were observed 60 min after a single IM dose of 150 mg flurbiprofen (n = 67) or 2 gm dipirone + 20 mg hyoscine N-butylbromide.
  
  
  RESULTS
  Both treatment modalities were well-tolerated and afforded significant pain relief. Flurbiprofen, however, was faster-acting and superior to dipirone + hyoscine in the overall evaluation of good and excellent therapeutic response rates.
  
  
  CONCLUSIONS
  The results of the study show that IM flurbiprofen is a useful alternative to dipirone + hyoscine N-butylbromide in the treatment of nephric colic.
authors.affiliation: Servicio de Urología, Hospital de Móstoles, Madrid, España.
authors.forename: M J
authors.initials: MJ
authors.lastname: Mora Durban
authors.forename: J
authors.initials: J
authors.lastname: Extramiana Cameno
authors.forename: M
authors.initials: M
authors.lastname: Arrizabalaga Moreno
authors.forename: P
authors.initials: P
authors.lastname: Paniagua Andrés
authors.forename: J
authors.initials: J
authors.lastname: Camp Herrero
authors.forename: J
authors.initials: J
authors.lastname: Milla Santos
authors.forename: F
authors.initials: F
authors.lastname: del Nogal Saez
authors.forename: F
authors.initials: F
authors.lastname: Gimeno Albo
authors.forename: E
authors.initials: E
authors.lastname: Moreno Carretero
authors.forename: R
authors.initials: R
authors.lastname: Domínguez Granados
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002086:Butylscopolammonium Bromide / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D003085:Colic / Q000188:drug therapy*; D004177:Dipyrone / Q000627:therapeutic use*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D005480:Flurbiprofen / Q000627:therapeutic use*; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012601:Scopolamine / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D002086:Butylscopolammonium Bromide; D005480:Flurbiprofen; D004177:Dipyrone; D012601:Scopolamine
vernacular_title: Flubiprofeno vs dipirona asociada a hioscina: eficacia analgésica en el cólico nefrítico.