Microscopic evaluation of bone-implant contact between hydroxyapatite, bioactive glass and tricalcium phosphate implanted in sheep diaphyseal defects.
In order to compare morphological discrepancies in bone-implant contact in vertebrates, cylinders of hydroxyapatite, bioactive glass and tricalcium phosphate were implanted in segmental defects of the tibia in sheep. Three types of visible bone-implant contact were observed microscopically at 4 months after implantation. The trabecular web-like bone-implant contact noted in tricalcium phosphate seemed superior to the disseminated patchy bone-implant contact in bioactive glass and the buttressed bone-implant contact in hydroxyapatite with respect to both bone ingrowth and bioresorption of the implant. Differences of physicochemical properties on the surface among the three kinds of bioceramic implants probably give rise to different types of bone-implant contact.
Gao
T J
TJ
Department of Clinical Medicine, University of Tampere, Finland.
Lindholm
T S
TS
Kommonen
B
B
Ragni
P
P
Paronzini
A
A
Lindholm
T C
TC
D000818:Animals; D001672:Biocompatible Materials; D016025:Bone Transplantation / Q000592:standards; D001842:Bone and Bones; D002130:Calcium Phosphates; D018483:Diaphyses / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000601:surgery; D017886:Durapatite; D005898:Glass; D016348:Osseointegration; D019736:Prostheses and Implants; D011859:Radiography; D012756:Sheep; D013194:Staining and Labeling; D013977:Tibia / Q000000981:diagnostic imaging
D001672:Biocompatible Materials; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; D017886:Durapatite; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous