title: Stridor in patients with HIV infection.
abstract: The immunodeficiency which results from HIV infection is associated with a range of opportunistic infections and tumors which may present with the symptoms of upper airways disease. This paper presents three cases of stridor from different causes in patients with HIV infection, all of whom recovered following treatment. The management of this problem requires consideration of the likely aetiology which, in those with advanced immunodeficiency, includes bacterial and fungal laryngitis and epiglottitis as well as rapidly growing laryngeal tumours. Recommendations for the treatment of those with HIV infection who present with severe or rapid-onset stridor should include a combination of aggressive airway intervention and broad-spectrum antibacterial and antifungal agents. Laryngeal biopsy for histology and culture is particularly important for those patients who fail to respond to the aforementioned treatment.
authors.affiliation: Regional Infectious Diseases Unit, City Hospital, Edinburgh, UK.
authors.forename: R B
authors.initials: RB
authors.lastname: Laing
authors.forename: P J
authors.initials: PJ
authors.lastname: Wardrop
authors.forename: P D
authors.initials: PD
authors.lastname: Welsby
authors.forename: R P
authors.initials: RP
authors.lastname: Brettle
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000328:Adult; D004826:Epiglottitis / Q000150:complications; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007827:Laryngitis / Q000150:complications; D016393:Lymphoma, B-Cell / Q000150:complications; D008297:Male; D012135:Respiratory Sounds / Q000209:etiology*