[Comparison between various methods of pregnancy screening during a large-scale ivermectin treatment in Cameroon].
During a mass treatment with ivermectin which is contraindicated to pregnant women, authors made a screening for pregnancy by questioning 2,580 women from 15 to 45 years old. 1,409 of these women were also interrogated by a female physician assisted by a native matron to detect pregnant women. In 1,798 women, at least one immunological pregnancy test has been used in the field. A nine months follow-up was made to check answers. Women's knowledge led to a good appreciation of pregnancy as they correctly appreciated their pregnancy from the second month: specificity was good (98%) but sensitivity was moderate (71%). Conclusions made by gynecological team after detailed questionnaire were more sensitive (80%), but specificity decrease dramatically to 59%. Combinations of several items in the questionnaire showed no benefit. Sensitivity of the various immunological pregnancy tests tried was included in 70 to 90% and specificity was varying from 87 to 97%. Simple questioning of women was the most efficient method (efficiency value was 94% against 63% for interview and 92% for pregnancy tests). However, the use of this method induced the risk that about 29% of women have been treated although they were pregnant.
Chippaux
J P
JP
Centre Pasteur du Cameroun, Yaoundé, Cameroun.
Gardon-Wendel
N
N
Ernould
J C
JC
Gardon
J
J
D000293:Adolescent; D000328:Adult; D002163:Cameroon; D000075202:Contraindications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007407:Interviews as Topic; D007559:Ivermectin / Q000627:therapeutic use*; D008403:Mass Screening; D008875:Middle Aged; D009855:Onchocerciasis / Q000517:prevention & control; D011159:Population Surveillance; D011247:Pregnancy; D011258:Pregnancy Tests; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires
D007559:Ivermectin
Comparaison entre différentes méthodes de dépistage des grossesses au cours de traitements par ivermectine à large échelle au Cameroun.