Mild form of acute herpes simplex encephalitis in childhood.
We describe two patients, aged 3.5 years and 15 years, with a mild form of herpes simplex encephalitis (HSE). The disease was characterized by convulsions and lymphocytic pleocytosis in the cerebrospinal fluid (CSF). Involvement of herpes simplex virus (HSV) was established by antibody measurements in serum and CSF. Recovery was complete with no antiviral drug administration. It appears that scrutinized serological work-up would widen our concept of mild forms of HSE, with a better prognosis and complete recovery.
Marton
R
R
Department of Neurology, Assaf Harofeh Medical Center, Zerifin, Israel.
Gotlieb-Stematsky
T
T
Klein
C
C
Lahat
E
E
Arlazoroff
A
A
D000208:Acute Disease; D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D002675:Child, Preschool; D018792:Encephalitis, Viral / Q000134:cerebrospinal fluid / Q000503:physiopathology* / Q000523:psychology; D006561:Herpes Simplex / Q000134:cerebrospinal fluid / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D008297:Male; D009460:Neurologic Examination; D011379:Prognosis; D018139:Simplexvirus / Q000276:immunology
D000914:Antibodies, Viral