Treatment of herpes zoster with Clinacanthus nutans (bi phaya yaw) extract.
A randomized, placebo-controlled trial of the efficacy of topical formulation of Clinacanthus nutans (Bi Phaya Yaw) extract was carried out in 51 patients with varicella-zoster virus infection. The study medication was applied five times daily for 7-14 days until the lesions were healed. The number of patients with lesion crusting within 3 days and with lesion healing within 7 days and 10 days were significantly greater in the C. nutans extract-treated group than the placebo group (p < 0.01). Pain scores were reduced more rapidly in the C. nutans extract-treated group than in the placebo group. There were no side effects of the study medication.
Sangkitporn
S
S
Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand.
Chaiwat
S
S
Balachandra
K
K
Na-Ayudhaya
T D
TD
Bunjob
M
M
Jayavasu
C
C
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006562:Herpes Zoster / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal