title: Three-dimensional structures of oligosaccharides.
abstract: Oligosaccharides represent a particularly challenging class of molecules for conformational analysis. Recent advances in experimental and theoretical methods have begun to yield further insight into their conformational behavior; however, general rules governing their conformational preferences have not yet emerged. X-ray and NMR techniques may provide vital insights into protein-bound oligosaccharide conformations, but these do not necessarily represent highly populated solution conformations. Moreover, an oligosaccharide's inherent flexibility and lack of strong intermolecular interactions places extreme demands on theoretical methods.
authors.affiliation: Complex Carbohydrate Research Center, University of Georgia, Athens 30602-4712, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Woods
mesh_terms: D002236:Carbohydrate Conformation; D018360:Crystallography, X-Ray; D006001:Glycoconjugates / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009010:Monte Carlo Method; D009844:Oligosaccharides / Q000737:chemistry*; D011485:Protein Binding
chemical_list: D006001:Glycoconjugates; D009844:Oligosaccharides