title: Fathers and sons: the Y chromosome and human evolution.
abstract: It should be possible to use Y chromosome DNA polymorphisms to trace paternal lineages for evolutionary and other studies, but progress in these areas has been slow because it has been difficult to find suitable markers. However, it is now possible to use selected, slowly evolving polymorphisms to draw a rudimentary Y chromosome tree, while more rapidly evolving polymorphisms allow most independent Y chromosomes to be distinguished. Different populations often have characteristically different Y chromosomes, and Y chromosome studies are soon likely to make a major contribution to our understanding of the origins of modern humans.
authors.affiliation: Department of Genetics, University of Leicester, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Jobling
authors.forename: C
authors.initials: C
authors.lastname: Tyler-Smith
mesh_terms: D001483:Base Sequence; D005075:Biological Evolution; D004247:DNA; D017931:DNA Primers; D005220:Fathers; D005544:Forecasting; D006801:Humans; D008969:Molecular Sequence Data; D009679:Nuclear Family; D011110:Polymorphism, Genetic; D014998:Y Chromosome
chemical_list: D017931:DNA Primers; D004247:DNA