Failure of immune sera to neutralize dengue-2 virus in intrathoracically inoculated Aedes aegypti.
Aedes aegypti became infected when inoculated with a mixture of dengue-2 virus and anti-dengue-2 antibodies, but not when they were exposed to the same mixture per os. This phenomenon merits more detailed investigation. Understanding why this difference in mosquito infection rate occurs may lead to improved dengue virus assays or provide insights into the nature of dengue virus-antibody interactions.
Putnam
J L
JL
Department of Entomology, University of Maryland, College Park 20742, USA.
Clark
G G
GG
Scott
T W
TW
D000330:Aedes / Q000276:immunology* / Q000821:virology; D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D003716:Dengue Virus / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D009500:Neutralization Tests
D000914:Antibodies, Viral