Early neonatal complications after elective preterm delivery in hypertensive pregnancies.
We evaluated the rates of short-term neonatal complications, neonatal brain damage or mortality in a group of 96 singleton pregnancies complicated by hypertension and electively delivered before 36 weeks gestation. The neonatal outcome of these pregnancies was compared with that of a matched control group of 192 uneventful pregnancies delivered because of spontaneous preterm labor or premature rupture of membranes. Although the rates of acidosis, apneoic crises, bradycardia and ventilatory support were higher among cases than controls, the risk of intraventricular hemorrhage, severe brain damage (grade III-IV intraventricular hemorrhage or periventricular leucomalacia) or neonatal mortality were comparable between the two groups. Neonatal complications were more frequent among infants born to mothers with severe hypertension or severe proteinuria. In conclusion, this study has shown that short term neonatal complications after elective preterm delivery in hypertensive pregnancies are increased in comparison with low risk controls. However, these complications, which were well managed in our intensive care nursery, did not affected neonatal mortality or severe brain damage.
Spinillo
A
A
Department of Obstetrics and Gynecology, University of Pavia School of Medicine, Italy.
Capuzzo
E
E
Stronati
M
M
Iasci
A
A
Ometto
A
A
Solerte
L
L
D000138:Acidosis / Q000453:epidemiology / Q000209:etiology; D000328:Adult; D001049:Apnea / Q000453:epidemiology / Q000209:etiology; D001919:Bradycardia / Q000453:epidemiology / Q000209:etiology; D016022:Case-Control Studies; D002543:Cerebral Hemorrhage / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005317:Fetal Growth Retardation / Q000150:complications / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000150:complications*; D015994:Incidence; D007226:Infant Mortality; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000453:epidemiology / Q000209:etiology*; D015999:Multivariate Analysis; D007752:Obstetric Labor, Premature / Q000150:complications*; D011225:Pre-Eclampsia / Q000150:complications / Q000209:etiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D011256:Pregnancy Outcome; D011379:Prognosis; D011446:Prospective Studies; D011507:Proteinuria / Q000150:complications / Q000209:etiology