alpha-Phosphonosulfonic acids: potent and selective inhibitors of squalene synthase.
Magnin
D R
DR
Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543, USA.
Biller
S A
SA
Chen
Y
Y
Dickson
J K
JK
Fryszman
O M
OM
Lawrence
R M
RM
Logan
J V
JV
Sieber-McMaster
E S
ES
Sulsky
R B
RB
Traeger
S C
SC
Hsieh
D C
DC
Lan
S J
SJ
Rinehart
J K
JK
Harrity
T W
TW
Jolibois
K G
KG
Kunselman
L K
LK
Rich
L C
LC
Slusarchyk
D A
DA
Ciosek
C P
CP
D000818:Animals; D002784:Cholesterol / Q000097:blood; D006224:Cricetinae; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors*; D000960:Hypolipidemic Agents / Q000737:chemistry / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D008968:Molecular Conformation; D051381:Rats; D013451:Sulfonic Acids / Q000737:chemistry / Q000494:pharmacology*
D000960:Hypolipidemic Agents; D013451:Sulfonic Acids; D002784:Cholesterol; D013186:Farnesyl-Diphosphate Farnesyltransferase