[Myositis, polysynovitis and pulmonary fibrosis: anti-Jo-1 syndrome].
Polymyositis/dermatomyositis are rare autoimmune diseases. Classification is usually performed according to the criteria of Bohan and Peter. The occurrence of myositis-specific autoantibodies has recently been described in inflammatory myopathies. Approximately half of the patients can now be classified by these specific autoantibodies. Several of these autoantibodies (anti-aminoacyl-tRNA synthetases, anti-SRP, anti-Mi2) are strongly associated with the clinical presentation. We may expect that in the future different subsets of these diseases will be increasingly identified by serum antibodies. We report on a patient with myopathy, pulmonary fibrosis and polysynovitis, a typical clinical presentation of the anti-Jo1 syndrome (anti-synthetase syndrome).
Perrenoud
F G
FG
Service de rhumatologie, Hôpital communal, La Chaux-de-Fonds, Lausanne.
Van Lindhoudt
D
D
Ochsner
F
F
Janzer
R C
RC
Ott
H
H
D000368:Aged; D000974:Antibodies, Antinuclear / Q000097:blood; D001327:Autoimmune Diseases / Q000276:immunology; D005260:Female; D006801:Humans; D017285:Polymyositis / Q000175:diagnosis*; D011658:Pulmonary Fibrosis / Q000175:diagnosis*; D013577:Syndrome; D013585:Synovitis / Q000175:diagnosis*
D000974:Antibodies, Antinuclear
Myosite, polysynovite et fibrose pulmonaire: le syndrome anti-Jo-1.