Neoglycoconjugates and their applications in glycobiology.
Within the past two years new developments in neoglycoconjugate formation have increased the accessibility and usefulness of these probes for the analyses of glycan structure and function. This article reviews several simple chemical and enzymatic methods for tagging oligosaccharides with chromophores, biotin, peptides, proteins and lipids, and describes some representative applications of these neoglycoconjugates.
Wong
S Y
SY
University of British Columbia, Vancouver, Canada.
D000911:Antibodies, Monoclonal / Q000276:immunology; D006001:Glycoconjugates / Q000737:chemistry*; D006017:Glycolipids / Q000737:chemistry*; D006020:Glycopeptides / Q000138:chemical synthesis / Q000737:chemistry; D006023:Glycoproteins / Q000737:chemistry*; D006031:Glycosylation; D015335:Molecular Probes; D009844:Oligosaccharides / Q000737:chemistry / Q000302:isolation & purification; D011134:Polysaccharides / Q000737:chemistry
D000911:Antibodies, Monoclonal; D006001:Glycoconjugates; D006017:Glycolipids; D006020:Glycopeptides; D006023:Glycoproteins; D015335:Molecular Probes; D009844:Oligosaccharides; D011134:Polysaccharides