title: Reevaluation of the results of iodine prophylaxis in eradication of endemic goiter in Macedonia.
abstract: In order to reevaluate effectiveness of iodine prophylaxis in Macedonia, epidemiological, ultrasonographic studies and estimation of urine excretion were performed. The results from the epidemiological survey in nongoitrogenic regions demonstrated goiter between 12.8% and 18%. Much higher prevalence of goiter was found in goitrogenic regions, between 20.8% and 60.8%. The incidence of goiter increased with age, and its prevalence is higher in girls when compared with the boys of the same age group. The thyroid volume estimated by ultrasonography was higher in children from goitrogenic regions when compared to nongoitrogenic. There was a good correlation between ultrasonographic volumetry data and size of the thyroid estimated by palpation. Urinary iodine excretion demonstrated low values in children from goitrogenic regions as indicator of iodine deficiency.
authors.affiliation: Institute of Pathophysiology and Nuclear Medicine, Medical Faculty, University Kiril and Metodij, Skopje, Macedonia.
authors.forename: B
authors.initials: B
authors.lastname: Karanfilski
authors.forename: G
authors.initials: G
authors.lastname: Sestakov
authors.forename: S
authors.initials: S
authors.lastname: Loparska
authors.forename: S
authors.initials: S
authors.lastname: Miceva-Ristevska
authors.forename: N
authors.initials: N
authors.lastname: Serafimov
authors.forename: I
authors.initials: I
authors.lastname: Tadzer
authors.forename: V
authors.initials: V
authors.lastname: Bogdanova
authors.forename: B
authors.initials: B
authors.lastname: Georgievska
authors.forename: N
authors.initials: N
authors.lastname: Simova
authors.forename: O
authors.initials: O
authors.lastname: Vaskova
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006043:Goiter, Endemic / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D007455:Iodine / Q000627:therapeutic use*; D008297:Male; D018843:Republic of North Macedonia / Q000453:epidemiology; D014463:Ultrasonography
chemical_list: D007455:Iodine