Multiple squamous-cell carcinomas of the scalp and chronic myeloid leukemia.
A 67-year-old patient with chronic myeloid leukemia for 4 years rapidly developed multiple squamous-cell carcinomas on the scalp. We discuss the role of chemotherapy, chronic immunosuppression, chronic sun exposure and of possible genetic factors.
Angeli-Besson
C
C
Department of Dermatology, CHU Timone, Marseille, France.
Koeppel
M C
MC
Jacquet
P
P
Andrac
L
L
Sayag
J
J
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology*; D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects / Q000627:therapeutic use; D016867:Immunocompromised Host; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D015122:Mercaptopurine / Q000009:adverse effects / Q000627:therapeutic use; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology*; D013472:Sunlight / Q000009:adverse effects
D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D015122:Mercaptopurine; D006918:Hydroxyurea