[Laboratory diagnosis of autoimmune sensorineural hearing loss with modified western blotting method].
Anti-membranous labyrinth proteins antibody were tested in suspectable autoimmune sensorineural hearing loss (ASNHL) with a modified western blotting method. 5 strongly positive bands (including 68,000) existed in at most 18 of 25 cases (72%). This method was found to be more sensitive than the routine one (40%). Anti-membranous proteins of Klebsiella pneumoniae antibodies were also found in 7 of 9 tested patients.
Zou
J
J
Institute of Otolaryngology, PLA General Hospital, Beijing.
Jiang
S
S
Gu
R
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000276:immunology*; D001426:Bacterial Proteins / Q000276:immunology; D015153:Blotting, Western; D007758:Ear, Inner / Q000276:immunology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000276:immunology*; D006801:Humans; D007711:Klebsiella pneumoniae / Q000276:immunology; D008297:Male; D008565:Membrane Proteins / Q000276:immunology*; D008875:Middle Aged
D000907:Antibodies, Bacterial; D001323:Autoantibodies; D001426:Bacterial Proteins; D008565:Membrane Proteins