MRI in thorotrastosis.
Magnetic resonance imaging (MRI) and computed tomography (CT) were performed in four patients with thorotrastosis. On CT scan, Thorotrast (thorium oxide) deposition was shown as high-density areas in the liver and spleen and the abdominal lymph nodes. These deposits were not found on MRIs. Splenic volume was significantly small due to atrophy. The contrast-noise ratio in the spleen on T1-weighted images was significantly lower. Thorotrast deposition does not affect MRI appearance; therefore it may be useful for the early detection of malignant tumors as a complication of thorotrastosis.
Ono
N
N
Second Department of Medicine, Kurume University School of Medicine, Japan.
Hirai
K
K
Ijyuin
H
H
Itano
S
S
Noguchi
H
H
Sakata
K
K
Aoki
Y
Y
Aritaka
T
T
Abe
H
H
Tanikawa
K
K
D000368:Aged; D056486:Chemical and Drug Induced Liver Injury; D003287:Contrast Media / Q000009:adverse effects* / Q000493:pharmacokinetics; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000139:chemically induced* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D013154:Spleen / Q000473:pathology; D013158:Splenic Diseases / Q000139:chemically induced* / Q000175:diagnosis; D013911:Thorium Dioxide / Q000009:adverse effects* / Q000493:pharmacokinetics; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D013911:Thorium Dioxide