[The dissolution of cystine lithiasis with n-acetylcysteine].
OBJECTIVE
The results of in situ dissolution of a cystine calculus is described. This approach was attempted in a female patient for whom surgery was not considered to be the best therapeutic option.


METHODS
An obstructive cystine calculus was treated by in situ litholysis using N-acetylcysteine applied locally via two percutaneous nephrostomies and adjuvant oral metaphylaxis. The patient had a long clinical history of lithiasis that had also required surgery and a family history of cystinuria.


RESULTS
In situ litholysis completely dissolved the cystine calculus and avoided the need for a complex surgery. The procedure and a pharmacological analysis are presented.


CONCLUSIONS
In our view, this procedure is practical, carries minimal morbidity and should be considered in the management of cystine calculus.
Benítez Navio
J
J
Servicio de Urología, Hospital Na. Sra. Alarcos, Ciudad Real, España.
Tudela Pavón
P
P
Laguna Urraca
G
G
Casanueva Luis
T
T
Ruana Encinar
M
M
Mata Guijarro
F
F
Gallardo Galán
C
C
D000111:Acetylcysteine / Q000008:administration & dosage*; D000328:Adult; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003553:Cystine / Q000032:analysis*; D003555:Cystinuria / Q000235:genetics / Q000628:therapy; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000737:chemistry / Q000628:therapy*; D012074:Remission Induction; D012996:Solutions; D013997:Time Factors
D012996:Solutions; D003553:Cystine; D000111:Acetylcysteine
Disolución de una litiasis cistínica con n-acetilcisteína.