Infiltrating ductal carcinoma of the breast: extensive intraductal component has no impact on lymph node involvement and survival.
The extensive intraductal component (EIC) in infiltrating ductal carcinoma (IDC) was reported to be a predictor of local recurrence. We investigated the influence of this histopathological parameter on nodal status and overall survival. In 115 patients suffering from an IDC with tumor stage FIGO I and II, 35 were EIC positive. We did not find a correlation with the nodal status. The mean follow up was 73 (+/- 38) months. EIC showed no influence on overall survival. Based on our findings, the presence of EIC is not a criterion for therapeutic decisions in IDC.
Joura
E A
EA
Department of Gynecology and Obstetrics, University of Vienna and Medical School, Austria.
Lösch
A
A
Kainz
C
C
Sam
C
C
Joura
E M
EM
Gitsch
G
G
Dadak
C
C
Breitenecker
G
G
D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D015996:Survival Rate