[Value of dobutamine technetium-99m-MIBI SPECT in detecting coronary artery disease].
The value of dobutamine 99mTc-MIBI SPECT (Dobu-ECT) for detecting coronary artery disease (CAD) was assessed in 39 patients. Compared with coronary angiography, the overall sensitivity and specificity of Dobu-ECT for detecting CAD were 92.9% and 90.9%. Of 13 patients with CAD without myocardial infarction, the sensitivity of Dobu-ECT was 84.6%. In detecting CAD with single, double or triple vessel diseases, the sensitivity of Dobu-ECT was 90.9%, 87.5% and 100% respectively. Furthermore, 88.2% of the patients (15/17) with multivessel (two or three vessels) diseases were correctly identified as having multivessel involvement. For detecting CAD, the sensitivity and specificity of dobutamine ECG were 53.5% and 82%. No serious side effects were observed in the study. The results showed that Dobu-ECT is a feasibie, safe and noninvasive method for diagnosing CAD.
Shen
D
D
Department of Cardiology, Beijing People's Hospital, Beijing Medical University.
Xu
C
C
Tian
Y
Y
D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004280:Dobutamine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
D004280:Dobutamine; D017256:Technetium Tc 99m Sestamibi