title: Comparison of continuous with intermittent bolus thermodilution cardiac output measurements.
abstract: BACKGROUND
  Few complete studies have been published to validate the agreement between continuous cardiac output and intermittent thermodilution cardiac output.
  
  
  OBJECTIVE
  To analyze the agreement between cardiac output measurements by the continuous thermodilution method and the intermittent bolus thermodilution method, using a continuous cardiac output catheter in postoperative cardiothoracic surgery patients.
  
  
  METHODS
  A convenience sample of 14 adult cardiothoracic surgical patients with thermodilution pulmonary artery catheters placed preoperatively was used. A total of 214 comparison measurements of cardiac output by both the continuous and intermittent thermodilution methods were taken on patient admission to the critical care unit, every 4 hours, and with any change greater than 10% from baseline readings.
  
  
  RESULTS
  The intraclass correlation between continuous cardiac output and intermittent cardiac output was .89. The limits of agreement were -1.34 to 1.18 L/min, indicating that in 95% of readings the difference between continuous cardiac output and intermittent cardiac output were within this range.
  
  
  CONCLUSIONS
  The continuous cardiac output monitoring method shows clinically acceptable agreement with the intermittent cardiac output method.
authors.affiliation: Palomar Medical Center, Escondido, Calif., USA.
authors.forename: C E
authors.initials: CE
authors.lastname: Ditmyer
authors.forename: M
authors.initials: M
authors.lastname: Shively
authors.forename: D B
authors.initials: DB
authors.lastname: Burns
authors.forename: R T
authors.initials: RT
authors.lastname: Reichman
mesh_terms: D000328:Adult; D000368:Aged; D006328:Cardiac Catheterization; D002302:Cardiac Output; D006348:Cardiac Surgical Procedures; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000191:economics / Q000379:methods* / Q000451:nursing; D015203:Reproducibility of Results; D013673:Technology Assessment, Biomedical; D013815:Thermodilution