In vitro dissolution studies on nifedipine capsules.
The in vitro dissolution rates of 5 and 10 mg nifedipine capsules from eight suppliers were measured in simulated gastric fluid using the rotating paddle apparatus. A total of fourteen products were tested and the performance was found to be satisfactory for all products (> 80% dissolution in 20 min).
Mehta
A C
AC
Department of Pharmacy, General Infirmary, Leeds, Yorkshire, U.K.
Hart-Davies
S
S
Kay
E A
EA
D002121:Calcium Channel Blockers / Q000737:chemistry*; D002214:Capsules; D055598:Chemical Phenomena; D002626:Chemistry, Pharmaceutical; D002627:Chemistry, Physical; D009543:Nifedipine / Q000737:chemistry*; D012995:Solubility
D002121:Calcium Channel Blockers; D002214:Capsules; D009543:Nifedipine