title: [Myositis, polysynovitis and pulmonary fibrosis: anti-Jo-1 syndrome].
abstract: Polymyositis/dermatomyositis are rare autoimmune diseases. Classification is usually performed according to the criteria of Bohan and Peter. The occurrence of myositis-specific autoantibodies has recently been described in inflammatory myopathies. Approximately half of the patients can now be classified by these specific autoantibodies. Several of these autoantibodies (anti-aminoacyl-tRNA synthetases, anti-SRP, anti-Mi2) are strongly associated with the clinical presentation. We may expect that in the future different subsets of these diseases will be increasingly identified by serum antibodies. We report on a patient with myopathy, pulmonary fibrosis and polysynovitis, a typical clinical presentation of the anti-Jo1 syndrome (anti-synthetase syndrome).
authors.affiliation: Service de rhumatologie, Hôpital communal, La Chaux-de-Fonds, Lausanne.
authors.forename: F G
authors.initials: FG
authors.lastname: Perrenoud
authors.forename: D
authors.initials: D
authors.lastname: Van Lindhoudt
authors.forename: F
authors.initials: F
authors.lastname: Ochsner
authors.forename: R C
authors.initials: RC
authors.lastname: Janzer
authors.forename: H
authors.initials: H
authors.lastname: Ott
mesh_terms: D000368:Aged; D000974:Antibodies, Antinuclear / Q000097:blood; D001327:Autoimmune Diseases / Q000276:immunology; D005260:Female; D006801:Humans; D017285:Polymyositis / Q000175:diagnosis*; D011658:Pulmonary Fibrosis / Q000175:diagnosis*; D013577:Syndrome; D013585:Synovitis / Q000175:diagnosis*
chemical_list: D000974:Antibodies, Antinuclear
vernacular_title: Myosite, polysynovite et fibrose pulmonaire: le syndrome anti-Jo-1.