"Tubulofilamentous particles" are not scrapie-specific and are unrelated to tubulovesicular structures.
"Tubulofilamentous particles" has been defined as "thick" tubules, apparently distinguishable from other cytoskeletal elements, in touch-preparations from scrapie- and Creutzfeldt-Jakob disease (CJD)-infected brains. I report here that "tubulofilamentous particles" are nonspecific findings unrelated to "tubulovesicular structures" (TVS) which are the only particles consistently observed in brains of naturally occurring and experimentally induced SSVE.
Liberski
P P
PP
Laboratory of Electron Microscopy and Neuropathology, Medical Academy Lódź, Poland.
D000818:Animals; D001921:Brain / Q000473:pathology* / Q000648:ultrastructure; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000473:pathology; D006224:Cricetinae; D016643:Encephalopathy, Bovine Spongiform / Q000473:pathology*; D008297:Male; D008647:Mesocricetus; D051379:Mice; D012608:Scrapie / Q000473:pathology*