Error propagation in reproduction of diploid organisms. A case study on single peaked landscapes.
Two versions of the diploid selection mutation equation as adapted to sequence space are studied. Focussing on diploid generalizations of the well-established single peaked landscape, quantitative effects of dominance on error thresholds in infinite populations are found, as well as unexpected qualitative features like multiple equilibria. Analogues of these phenomena are also recovered in stochastic versions for finite populations.
Wiehe
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Institut für Molekulare Biotechnologie, Jena, Germany.
Baake
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Schuster
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D000818:Animals; D004171:Diploidy; D008957:Models, Genetic; D009154:Mutation / Q000235:genetics*; D012098:Reproduction; D012641:Selection, Genetic