Ocular manifestation of hairy cell leukemia with dramatic response to 2-chloro-deoxy-adenosine.
OBJECTIVE
To demonstrate that hairy cell leukemia may involve the eye.


METHODS
We examined a patient who had a unique ocular manifestation of hairy cell leukemia with severe panuveitis in one eye and leukemic retinopathy in the fellow eye.


RESULTS
Therapy with 2-chloro-deoxy-adenosine, a drug recently introduced for treatment of hairy cell leukemia, led to dramatic improvement of the ocular complications.


CONCLUSIONS
Hairy cell leukemia may involve the eye and ocular symptoms may respond to systemic treatment with 2-chloro-deoxy-adenosine.
Robinson
A
A
Department of Ophthalmology, Golda Medical Center, Hasharon Hospital, Petach-Tikva, Israel.
Eting
E
E
Zeidman
A
A
Djaldetti
M
M
Mittelman
M
M
Savir
H
H
D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001402:B-Lymphocytes / Q000648:ultrastructure; D017338:Cladribine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D007943:Leukemia, Hairy Cell / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D014605:Uveitis / Q000150:complications
D000970:Antineoplastic Agents; D017338:Cladribine