title: Effects of progesterone on the ultrastructure of the golden hamster parathyroid gland.
abstract: The ultrastructure of the parathyroid glands in golden hamsters after administration of progesterone was investigated. In the parathyroid glands of the female hamsters after administration of progesterone, the mean serum calcium concentration was significantly higher when compared to that of the control hamsters. In the male experimental hamsters, the percentage area occupied by Golgi complexes and lipid droplets was significantly increased when compared to that of the control hamsters, respectively. In the female hamsters after administration of progesterone, the percentage area occupied by large vacuolar bodies was significantly decreased when compared to that of the control hamsters. In the male and female experimental hamsters, the mean number of secretory granules per 100 microns2 of cytoplasm showed a significant increase compared with that of the male and female control hamsters, respectively. These findings suggest that the secretory activity of the parathyroid glands may be stimulated in response to hypocalcemia induced by progesterone.
authors.affiliation: College of Medical Sciences, Gifu University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Emura
authors.forename: D
authors.initials: D
authors.lastname: Hayakawa
authors.forename: T
authors.initials: T
authors.lastname: Yamahira
authors.forename: K
authors.initials: K
authors.lastname: Terasawa
authors.forename: A
authors.initials: A
authors.lastname: Tamada
authors.forename: M
authors.initials: M
authors.lastname: Arakawa
authors.forename: H
authors.initials: H
authors.lastname: Isono
authors.forename: S
authors.initials: S
authors.lastname: Shoumura
mesh_terms: D000818:Animals; D002118:Calcium / Q000097:blood; D006224:Cricetinae; D003594:Cytoplasmic Granules / Q000187:drug effects / Q000648:ultrastructure; D005260:Female; D006056:Golgi Apparatus / Q000187:drug effects / Q000648:ultrastructure; D008247:Lysosomes / Q000187:drug effects / Q000648:ultrastructure; D008297:Male; D008647:Mesocricetus; D010280:Parathyroid Glands / Q000187:drug effects / Q000648:ultrastructure*; D011374:Progesterone / Q000494:pharmacology*; D012727:Sex Characteristics; D014617:Vacuoles / Q000187:drug effects / Q000648:ultrastructure
chemical_list: D011374:Progesterone; D002118:Calcium