title: [Moderately differentiated neuroendocrine carcinoma of the larynx].
abstract: We present a case of moderately differentiated neuroendocrine carcinoma of the larynx. These tumors represent 0.6% of all laryngeal carcinomas. Histological diagnosis requires the use of immunohistochemical methods, the tumoral cells presenting positivity for epithelial markers (cytokeratin) and neuroendocrine markers (chromogranin). Clinically, their location is supraglottic and they affect mainly males between the 6th-7th decades of life. The prognosis is better than that of squamous carcinoma or adenocarcinoma. The differential diagnosis must be made with granular cell tumor and paragangliomas.
authors.affiliation: Servicio de Anatomía Patológica, Hospital General Universitario, Valencia.
authors.forename: I
authors.initials: I
authors.lastname: Salvador Villalba
authors.forename: E
authors.initials: E
authors.lastname: Martínez Leandro
authors.forename: P
authors.initials: P
authors.lastname: Alemany Monraval
authors.forename: M
authors.initials: M
authors.lastname: Martorell Cebollada
authors.forename: J
authors.initials: J
authors.lastname: Basterra Alegre
mesh_terms: D018278:Carcinoma, Neuroendocrine / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D007830:Larynx / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D008875:Middle Aged
vernacular_title: Carcinoma neuroendocrino medianamente diferenciado de laringe. A propósito de un caso.