Trichorzins HA and MA, antibiotic peptides from Trichoderma harzianum. II. Sequence determination.
A series of 18-residue antibiotic-antifungal peptides, trichorzins HA and MA, were isolated from Trichoderma harzianum strains exhibiting antagonistic properties against phytopathogenic fungi. The sequences of the nine major pure peptides isolated by HPLC were determined by positive ion FAB-MS data and two-dimensional NMR measurements, including COSY, HOHAHA, ROESY and 1H-13C LRCOSY experiments.
Hlimi
S
S
Laboratoire de Chimie des Substances Naturelles, URA 401 CNRS, Muséum National d'Histoire Naturelle, Paris, France.
Rebuffat
S
S
Goulard
C
C
Duchamp
S
S
Bodo
B
B
D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry*; D017421:Sequence Analysis; D017385:Sequence Homology; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014242:Trichoderma / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D010455:Peptides