An elastic computerized brain atlas for the analysis of clinical PET/SPET data.
An elastic computerized brain atlas was developed for the analysis of positron emission tomography/single-photon emission tomography (PET/SPET) data. It consists of a set of digital anatomical contours and a template of regions of interest, schematically describing the brain, derived from a currently used anatomical/functional brain atlas. A warping algorithm, matching equivalent contours, was implemented to elastically fit the atlas to individual brain images. The elastic computerized brain atlas was applied to representative magnetic resonance imaging (MRI)-PET/SPET studies, MRI providing the anatomical information used by the matching procedure. The atlas is suited for clinical use in a nuclear medicine environment.
Rizzo
G
G
Department of Nuclear Medicine Scientific Institute H San Raffaele, INB-CNR, University of Milan, Italy.
Gilardi
M C
MC
Prinster
A
A
Grassi
F
F
Scotti
G
G
Cerutti
S
S
Fazio
F
F
D001921:Brain / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D001931:Brain Mapping; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D012984:Software; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon