title: Ofloxacin eardrop treatment for active chronic suppurative otitis media: prospective randomized study.
abstract: This report presents a prospective randomized study of 0.3 percent ofloxacin eardrops for the treatment of active chronic suppurative otitis media. Twenty-nine patients were treated with ofloxacin eardrops for 1 week, and another 27 patients were treated with Augmentin for 1 week. One week after completion of treatment, 22 (76%) patients of the group treated with ofloxacin had dry ears, and only seven (26%) patients treated with Augmentin had dry ears. Ofloxacin eardrops were effective in the initial treatment of active chronic suppurative otitis media.
authors.affiliation: Department of Surgery, University of Hong Kong, Queen Mary Hospital, Hong Kong.
authors.forename: P W
authors.initials: PW
authors.lastname: Yuen
authors.forename: S K
authors.initials: SK
authors.lastname: Lau
authors.forename: P Y
authors.initials: PY
authors.lastname: Chau
authors.forename: Y
authors.initials: Y
authors.lastname: Hui
authors.forename: S F
authors.initials: SF
authors.lastname: Wong
authors.forename: S
authors.initials: S
authors.lastname: Wong
authors.forename: W I
authors.initials: WI
authors.lastname: Wei
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use; D019980:Amoxicillin-Potassium Clavulanate Combination; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D002969:Clavulanic Acids / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007322:Instillation, Drug; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use*; D010035:Otitis Media, Suppurative / Q000188:drug therapy* / Q000382:microbiology; D011446:Prospective Studies; D012720:Severity of Illness Index
chemical_list: D000890:Anti-Infective Agents; D002969:Clavulanic Acids; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin; D015242:Ofloxacin