Serotonin, reserpine, and motility in Mesocestoides tetrathyridia. An experimental spectrofluorometry and immunocytochemistry study.
The relationship between serotonin (5-HT) and motility in tetrathyridia of Mesocestoides vogae (syn. M. corti) was studied with the aid of reserpine. Reserpine decreases the content of 5-HT as measured spectrofluorometrically and immunocytochemically and, furthermore, inhibits the motility, thus indicating a connection between the two. The results support the hypothesis about 5-HT being an excitatory neurotransmitter of motor activity in M. vogue. New neuroanatomical details were revealed by immunocytochemical staining.
Terenina
N B
NB
Institute of Parasitology of the Russian Academy of Sciences, Moscow, Russia.
Gustafsson
M K
MK
Reuter
M
M
D000818:Animals; D007150:Immunohistochemistry; D008645:Mesocestoides / Q000187:drug effects / Q000502:physiology*; D051379:Mice; D009068:Movement; D012110:Reserpine / Q000494:pharmacology*; D012701:Serotonin / Q000502:physiology*; D013050:Spectrometry, Fluorescence
D012701:Serotonin; D012110:Reserpine