Red cell 6-phosphogluconate dehydrogenase polymorphism in the Gadaba of Andhra Pradesh (India). Report of new variant phenotypes.
Blood samples from 1000 unrelated, adult individuals of the Gadaba tribal population were screened for 6-phosphogluconate dehydrogenase. We report the occurrence of a new fast moving variant, which is caused by the allele PGD* Gadaba. This allele is reported for the first time among the tribal populations of Andhra Pradesh. Its frequency comes to 0.0115, and it was observed in heterozygous (2.10%) and homozygous (0.10%) conditions.
Rao
P M
PM
Department of Anthropology, Government Degree College, Srikakulam, India.
Kirk
R L
RL
Busi
B R
BR
Reddi
G G
GG
Ramana
G V
GV
D000328:Adult; D000483:Alleles; D003906:Developing Countries; D004912:Erythrocytes / Q000201:enzymology*; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D014644:Genetic Variation; D005828:Genetics, Population; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007194:India; D008297:Male; D010641:Phenotype; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics*
D010734:Phosphogluconate Dehydrogenase