Treatment of migraine headache after ocular surgery with intravenous metoclopramide hydrochloride.
OBJECTIVE
To alert ophthalmologists that prolonged or severe postoperative periocular pain and nausea may be caused by migraine.


METHODS
We examined two patients who had a history of migraine and had severe episodes of prolonged periocular pain and nausea after ocular procedures. Both patients experienced symptoms similar to their previous migraine attacks. In neither was pain alleviated by routine analgesics.


RESULTS
Each patient had relief of symptoms within two minutes after intravenous delivery of metoclopramide hydrochloride.


CONCLUSIONS
Ophthalmologists should consider the diagnosis of postoperative migraine in similar patients and provide specific therapy such as intravenous metoclopramide hydrochloride.
MacCumber
M W
MW
Duke University Eye Center, Durham, NC 27710, USA.
Jaffe
G J
GJ
McCuen
B W
BW
D000328:Adult; D002387:Cataract Extraction / Q000009:adverse effects*; D018492:Dopamine Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007910:Lenses, Intraocular; D008297:Male; D008787:Metoclopramide / Q000008:administration & dosage / Q000627:therapeutic use*; D008881:Migraine Disorders / Q000188:drug therapy* / Q000209:etiology; D009325:Nausea / Q000188:drug therapy / Q000209:etiology; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology; D012163:Retinal Detachment / Q000601:surgery; D012166:Retinal Hemorrhage / Q000601:surgery; D014821:Vitrectomy / Q000009:adverse effects*
D018492:Dopamine Antagonists; D008787:Metoclopramide