title: Neosporosis-associated abortion in a dairy goat.
abstract: Neospora canium tachyzoites and tissue cysts were found in tissues of a goat fetus aborted after 3.5 months of gestation. The fetus had hydrocephalus and a hypoplastic cerebellum. The predominant lesion in the fetus was severe encephalitis associated with numerous N canium tissue cysts. Parasites in fetal tissues reacted positively with N caninum antibodies in immunohistochemical tests. The doe was clinically normal and had a 1:800 antibody titer to N caninum as determined by use of an indirect fluorescent antibody test 9 months after abortion. Five of 77 other does from this herd also had indirect fluorescent antbody titers to N caninum that were > or = 1:100.
authors.affiliation: Parasite Biology and Epidemiology Laboratory, USDA, Beltsville, MD 20705-2350, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
authors.forename: J A
authors.initials: JA
authors.lastname: Morales
authors.forename: P
authors.initials: P
authors.lastname: Villalobos
authors.forename: D S
authors.initials: DS
authors.lastname: Lindsay
authors.forename: B L
authors.initials: BL
authors.lastname: Blagburn
authors.forename: M J
authors.initials: MJ
authors.lastname: Topper
mesh_terms: D000034:Abortion, Veterinary / Q000469:parasitology*; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D003048:Coccidiosis / Q000469:parasitology / Q000662:veterinary*; D005260:Female; D005333:Fetus / Q000469:parasitology* / Q000473:pathology; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D015511:Goat Diseases / Q000469:parasitology*; D006041:Goats; D007150:Immunohistochemistry; D008297:Male; D018688:Neospora / Q000276:immunology / Q000302:isolation & purification*; D011247:Pregnancy
chemical_list: D000913:Antibodies, Protozoan