title: Childhood neuroborreliosis: clinicoradiological correlation.
abstract: We report the cranial CT and MRI findings in three children with Lyme disease (neuroborreliosis). The neuroimaging findings in children have been rarely reported. We found cranial MRI far superior to cranial CT. Ring-enhancing lesions have been described in acute disseminating encephalomyelitis and multiple sclerosis but not in neuroborreliosis. Although other infectious and inflammatory diseases cannot be excluded, Lyme disease should be included in the differential diagnosis and put forward as being the most likely diagnosis in the appropriate clinical setting. Gadopentetate dimeglumine is helpful in assessing the response to antibiotic treatment.
authors.affiliation: Department of Radiology, University Hospitals K.U. Leuven, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Demaerel
authors.forename: G
authors.initials: G
authors.lastname: Wilms
authors.forename: K
authors.initials: K
authors.lastname: Casteels
authors.forename: P
authors.initials: P
authors.lastname: Casaer
authors.forename: J
authors.initials: J
authors.lastname: Silberstein
authors.forename: A L
authors.initials: AL
authors.lastname: Baert
mesh_terms: D001921:Brain / Q000473:pathology*; D002648:Child; D003287:Contrast Media; D003937:Diagnosis, Differential; D004338:Drug Combinations; D004679:Encephalomyelitis / Q000175:diagnosis*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D008536:Meglumine; D009460:Neurologic Examination; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D004338:Drug Combinations; D009942:Organometallic Compounds; D008536:Meglumine; D004369:Pentetic Acid; D019786:Gadolinium DTPA