title: DNA neosynthesis in Auerbach plexus ganglia isolated from the rat hypertrophic gut: an electrophoretic analysis.
abstract: We analysed using electrophoresis the total genomic DNA extracted from isolated Auerbach plexus ganglia of the hypertrophic duodenum upstream from a partial experimental stenosis. Results indicated the presence of two extra-bands migrating below the high molecular weight DNA. suggesting that DNA amplification is the basic mechanism of the DNA neosynthesis previously observed in myenteric neurons.
authors.affiliation: Dipartimento di Anatomia e Fisiologia Umana, Universita degli Studi di Torino, Italy.
authors.forename: M G
authors.initials: MG
authors.lastname: Giacobini Robecchi
authors.forename: P
authors.initials: P
authors.lastname: Borrione
authors.forename: M
authors.initials: M
authors.lastname: Canavese
authors.forename: S
authors.initials: S
authors.lastname: Geuna
authors.forename: A
authors.initials: A
authors.lastname: Paraninfo
authors.forename: A
authors.initials: A
authors.lastname: Poncino
authors.forename: L
authors.initials: L
authors.lastname: Silengo
mesh_terms: D000818:Animals; D004247:DNA / Q000096:biosynthesis*; D004171:Diploidy; D004586:Electrophoresis; D005725:Ganglia, Autonomic / Q000378:metabolism*; D016678:Genome; D006984:Hypertrophy; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000294:innervation / Q000473:pathology; D008297:Male; D009197:Myenteric Plexus / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004247:DNA