title: [Clastogenic activity of dietary sugar substitutes].
abstract: The present paper describes the possible clastogenic activity of the following synthetic sugar substitutes, such as cyclamate in daily doses of 11 and 110 mg/kg, saccharin, 5 and 50 mg/kg, acesulfam, 15 and 150 mg/kg, sucralose, 15 and 150 mg/kg, aspartame, 40 and 400 mg/kg, orally given to C57Bl/6 mice during 5 days. No clastogenic activity was found in the compounds tested.
authors.forename: A D
authors.initials: AD
authors.lastname: Durnev
authors.forename: A V
authors.initials: AV
authors.lastname: Oreshchenko
authors.forename: A V
authors.initials: AV
authors.lastname: Kulakova
authors.forename: N F
authors.initials: NF
authors.lastname: Beresten'
authors.forename: S B
authors.initials: SB
authors.lastname: Seredenin
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations; D004032:Diet; D004305:Dose-Response Relationship, Drug; D051379:Mice; D008810:Mice, Inbred C57BL; D009152:Mutagenicity Tests; D013549:Sweetening Agents / Q000633:toxicity*
chemical_list: D013549:Sweetening Agents
vernacular_title: Issledovanie klastogennoĭ aktivnosti pishchevykh sakharozameniteleĭ.