title: [First evaluation of the Variant haemoglobin analyzer (Bio-Rad)].
abstract: OBJECTIVE
  The analytical performance of the first automated HPLC analyzer of haemoglobins A2 and Foetal is presented.
  
  
  RESULTS
  The analyzer shows an imprecision within-run between 0.66-2.7% and between-run 1.8-6.44. Correlation index with manual methods were r = 0.965 (p < 0.005) for Hb A2 and r = 0.999 (p < 0.0001) for Foetal Hb and the reference values of an adult population were established; Hb A2 (1.98-2.94%) and Hb F (0-0.95%). Several chromatograms of haemoglobinopathies are presented.
  
  
  CONCLUSIONS
  These results validate the method to resolve the increased demand of these parameters.
authors.affiliation: Laboratorio y Servicio de Hematología, Hospital Universitario Materno-Infantil del Valle d'Hebrón, Barcelona.
authors.forename: C
authors.initials: C
authors.lastname: Aulesa
authors.forename: J
authors.initials: J
authors.lastname: Comellas
authors.forename: M
authors.initials: M
authors.lastname: Sentis
authors.forename: J J
authors.initials: JJ
authors.lastname: Ortega
mesh_terms: D000328:Adult; D002851:Chromatography, High Pressure Liquid; D005319:Fetal Hemoglobin / Q000032:analysis; D006441:Hemoglobin A / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D012016:Reference Values; D012680:Sensitivity and Specificity; D017086:beta-Thalassemia / Q000097:blood
chemical_list: D006454:Hemoglobins; D006441:Hemoglobin A; D005319:Fetal Hemoglobin
vernacular_title: Primera evaluación del analizador de hemoglobinas Variant (Bio-Rad).