[Anti-edematous action of EDTA, its effect on lipid peroxidation intensity and various components of the antioxidant system of the lungs in rats exposed to NO2].
It has been studied how preventive administration of EDTA influences toxic NO2- induced pulmonary edema and disturbances in antioxidant systems. The compound in question, being preventively administered, has exerted a significant antiedematic effect as a result of a decrease in lipid peroxidation intensity and protection of the most important substrate components of the nonenzymatic antioxidant system from the oxidation effect.
Galkin
B N
BN
Golovenko
N Ia
NIa
Ostrov
V E
VE
Filippova
T O
TO
Tikhonov
A V
AV
Barinov
V A
VA
Chernienko
I E
IE
D000818:Animals; D000931:Antidotes / Q000494:pharmacology*; D000975:Antioxidants / Q000378:metabolism*; D004492:Edetic Acid / Q000737:chemistry / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D051379:Mice; D009585:Nitrogen Dioxide / Q000037:antagonists & inhibitors*; D011654:Pulmonary Edema / Q000188:drug therapy*; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000737:chemistry
D000931:Antidotes; D000975:Antioxidants; D004492:Edetic Acid; D012964:Sodium; D009585:Nitrogen Dioxide
Protivootechnoe deĭstvie EDTA i ee vliianie na intensivnost' perekisnogo okisleniia lipidov i nekotorye komponenty antioksidantnoĭ sistemy legkikh krys pri vozdeĭstvii NO2.