title: The effect of sucrose-containing chewing-gum use on in situ enamel lesion remineralization.
abstract: Two independent cross-over studies have now been carried out to evaluate the effect of a regime of chewing sucrose-containing gum on enamel lesion remineralization. The first study has been reported in detail elsewhere. This further study aimed to increase the data set with an additional 13 volunteers. Similar protocols were followed in both studies. Weighted averages from the two studies showed delta z values corresponding to 16.8% remineralization for the gum versus 11.6% remineralization for the control (p = 0.046, two-sided). A significant difference between test and control was evident for lesion body (p = 0.0004, two-sided) but not for surface zone (p = 0.32, two-sided).
authors.affiliation: Department of Oral Sciences, University of Glasgow Dental School, UK.
authors.forename: A F
authors.initials: AF
authors.lastname: Hall
authors.forename: S L
authors.initials: SL
authors.lastname: Creanor
authors.forename: R
authors.initials: R
authors.lastname: Strang
authors.forename: W H
authors.initials: WH
authors.lastname: Gilmour
authors.forename: R H
authors.initials: RH
authors.lastname: Foye
authors.forename: J
authors.initials: J
authors.lastname: Brown
authors.forename: D A
authors.initials: DA
authors.lastname: Geddes
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002638:Chewing Gum; D018592:Cross-Over Studies; D003720:Densitometry; D005500:Follow-Up Studies; D006801:Humans; D012044:Regression Analysis; D012969:Sodium Fluoride / Q000627:therapeutic use; D013395:Sucrose; D017001:Tooth Demineralization / Q000628:therapy*; D014089:Tooth Remineralization / Q000379:methods*
chemical_list: D002638:Chewing Gum; D013395:Sucrose; D012969:Sodium Fluoride