title: [Hyperintense brain lesions on T1-weighted MRI after parenteral nutrition].
abstract: We experienced five children having T1-shortening lesions in basal ganglia or thalami on magnetic resonance imaging (MRI), which were supposed to be caused by manganese (Mn) overdoses. Instead of the presence of above mentioned lesions, no neurological manifestations corresponding to them had developed in all patients. This observation suggests that a MRI is useful for detecting the side effects caused by overdoses of Mn in patients having parenteral nutrition.
authors.affiliation: Department of Pediatrics, Urafune Hospital of Yokohama City University, Kanagawa.
authors.forename: Y
authors.initials: Y
authors.lastname: Saitoh
authors.forename: S
authors.initials: S
authors.lastname: Kimura
authors.forename: A
authors.initials: A
authors.lastname: Nezu
authors.forename: N
authors.initials: N
authors.lastname: Ohtsuki
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: H
authors.initials: H
authors.lastname: Osaka
authors.forename: S
authors.initials: S
authors.lastname: Uehara
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D002648:Child; D062787:Drug Overdose; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008345:Manganese / Q000008:administration & dosage; D020149:Manganese Poisoning; D010288:Parenteral Nutrition; D011041:Poisoning / Q000175:diagnosis
chemical_list: D008345:Manganese