Fractal dimension analysis of the oscillated blood flow with a vibrating flow pump.
To analyze the hemodynamic parameters during circulation with oscillated blood flow, nonlinear mathematical analyzing techniques, including fractal theory, were utilized. Vibrating flow pumps (VFP) were implanted as a left heart bypass, and the ascending aorta was clamped to constitute the total left heart circulation with oscillated blood flow in acute animal experiments using 7 adult goats. Using nonlinear mathematical analyzing techniques, reconstructed attractors of the arterial blood pressure waveform in the phase space during natural circulation and oscillated circulation were analyzed. Using the Grassberger-Procaccia correlation dimension analyzing technique, fractal dimension analysis of the reconstructed attractor was performed. During VFP bypass, lower fractal dimensions of the reconstructed attractor were shown compared with those during natural heart circulation. The results suggest that lower dimensional chaotic dynamics contributed to the circulation with oscillated blood flow.
Yambe
T
T
Department of Medical Engineering, Tohoku University, Sendai, Japan.
Sonobe
T
T
Naganuma
S
S
Kobayashi
S
S
Nanka
S
S
Akiho
H
H
Kakinuma
Y
Y
Mitsuoka
M
M
Chiba
S
S
Ohsawa
N
N
D000818:Animals; D001011:Aorta / Q000502:physiology; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D003326:Coronary Circulation / Q000502:physiology; D004562:Electrocardiography; D017709:Fractals; D006041:Goats; D018611:Heart Bypass, Left; D006354:Heart, Artificial / Q000592:standards*; D006439:Hemodynamics; D008961:Models, Structural; D011673:Pulsatile Flow