title: D-Dimer in intra-uterine growth retardation and gestational hypertension.
abstract: Pregnancy is sometime related to thromboembolic complications (1) and alterations in different hemostatic parameters have been reported in pregnancy (2-4). In particular, a progressive increase in fibrinogen and D-dimer levels occurs during normal pregnancy (5-9). D-dimer levels may be predictive for some complications such as preeclampsia (10) and they have been also reported to be useful for diagnosis of abruptio placentae (6). However, it remains to be established if common ELISA for D-dimer are able to discriminate pathologic samples in conditions such as intrauterine growth retardation (IUGR) or gestational hypertension (GH). Aim of the present study has been to evaluate the behavior of D-dimer in pregnant women with IUGR and GH.
authors.affiliation: Istituto di Clinica Medica Generale e Cardiologia, University of Florence, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Francalanci
authors.forename: P
authors.initials: P
authors.lastname: Comeglio
authors.forename: A A
authors.initials: AA
authors.lastname: Liotta
authors.forename: A P
authors.initials: AP
authors.lastname: Cellai
authors.forename: S
authors.initials: S
authors.lastname: Fedi
authors.forename: E
authors.initials: E
authors.lastname: Parretti
authors.forename: G
authors.initials: G
authors.lastname: Mello
authors.forename: D
authors.initials: D
authors.lastname: Prisco
authors.forename: R
authors.initials: R
authors.lastname: Abbate
mesh_terms: D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005317:Fetal Growth Retardation / Q000097:blood*; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy
chemical_list: D005338:Fibrin Fibrinogen Degradation Products