title: Study of 45 cases of nasopharyngeal carcinoma with dermatomyositis.
abstract: The authors have conducted a study of 61 cases of nasopharyngeal carcinoma (NPC) with dermatomyositis (DM) admitted to the hospital between April 1964 and May 1989 and accounting for 0.027% (61/226, 183) of all the malignant tumors at the hospital and 0.086% (61/70,899) of the nasopharyngeal carcinoma cases, during that time period. We have analyzed 45 cases with complete data, using equal number of age-, sex-, and stage-matched cases with only NPC as control. The findings show a 5- and 10-year survival rate and distant metastatic rate of 50.4, 34.5, and 40.5% respectively, for NPC with DM, and 57.8, 55.2, and 56.5% for controls. The results indicated that the radiotherapy with prednisone treatment not only is quite effective but also will not result in a significantly increased rate of distant metastasis.
authors.affiliation: Department of Radiotherapy, Sun Yat-sen University of Medical Sciences, Guangzhou, Peoples Republic of China.
authors.forename: W J
authors.initials: WJ
authors.lastname: Hu
authors.forename: D L
authors.initials: DL
authors.lastname: Chen
authors.forename: H Q
authors.initials: HQ
authors.lastname: Min
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary; D016022:Case-Control Studies; D003131:Combined Modality Therapy; D003882:Dermatomyositis / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D011241:Prednisone / Q000627:therapeutic use; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011241:Prednisone