title: Bone changes in postmenopausal Thai women with or without hormonal replacement therapy.
abstract: Bone mass measurement was performed in 95 healthy postmenopausal women to assess the effect of hormonal replacement therapy (HRT) on bone changes. Women in the study group (51/95) received estrogen with or without progestin. The control group (44/95) did not receive any hormone regimen. The measurement was done at lumbar spines (L1-L4) and hip by dual energy X-ray absorptiometer at 0, 6 and 12 months. The results revealed significantly higher per cent changes of bone density of lumbar spines and hip, at 12 months, in the study group than in the control. (
  
  
  METHODS
  Lumbar Spine +1.76%, Hip +3.57%;
  
  
  METHODS
  Lumbar spines -2.32%, Hip +1.32%, P < 0.05). In conclusion, this study showed the value of hormonal replacement therapy for prevention of postmenopausal bone loss in Thai women.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: K
authors.initials: K
authors.lastname: Limpaphayom
authors.forename: N
authors.initials: N
authors.lastname: Taechakraichana
authors.forename: M
authors.initials: M
authors.lastname: Poshyachinda
authors.forename: U
authors.initials: U
authors.lastname: Jaisamrarn
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D015519:Bone Density / Q000187:drug effects*; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy* / Q000517:prevention & control; D017698:Postmenopause; D011446:Prospective Studies; D013785:Thailand; D016896:Treatment Outcome
chemical_list: D004967:Estrogens