title: New version of flow-transformed pulsatile total artificial heart with no electrical switching valve.
abstract: The flow-transformed pulsatile total artificial heart (FTPTAH) is a new pulsatile total artificial heart that consists of a single continuous flow rotary blood pump and blood flow switching valves. It can perfuse the pulmonary and the systemic circulation alternately with pulsatile flow. A new version of the FTPTAH, which consists of one undulation pump (UP), 4 jellyfish valves, and a compensatory chamber, has been proposed. The UP is a reversible continuous flow blood pump, and flow transformation is caused by switching the direction of the motor rotation so that no electrical flow switching valve is needed. A prototype model could perfuse alternately pulmonary and systemic circulation with 3.0 L/min in a mock circulation. Unoxygenated blood in the UP at the end of pulmonary circulation will be stored in the compensatory chamber by shifting a flexible membrane to the direction of the left atrium (LA); therefore, the blood is not sent to the systemic circulation.
authors.affiliation: Research Center for Advanced Science and Technology, University of Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Isoyama
authors.forename: K
authors.initials: K
authors.lastname: Imachi
authors.forename: Y
authors.initials: Y
authors.lastname: Abe
authors.forename: T
authors.initials: T
authors.lastname: Chinzei
authors.forename: K
authors.initials: K
authors.lastname: Imanishi
authors.forename: K
authors.initials: K
authors.lastname: Mabuchi
authors.forename: H
authors.initials: H
authors.lastname: Matsuura
authors.forename: I
authors.initials: I
authors.lastname: Fujimasa
mesh_terms: D016275:Atrial Function; D001783:Blood Flow Velocity / Q000502:physiology; D004867:Equipment Design; D006351:Heart Valves; D006354:Heart, Artificial / Q000592:standards* / Q000639:trends; D010101:Oxygen Consumption; D011652:Pulmonary Circulation / Q000502:physiology; D011673:Pulsatile Flow; D012399:Rotation