title: Age at onset of geriatric depression and sensorineural hearing deficits.
abstract: Comorbidity of sensorineural hearing deficits and both depressive states and dementia in late life provided the rationale for this investigation. Cognitively intact geriatric major depressives (n = 43) were assessed for depressive symptoms, cognitive performance, and delusions while symptomatic, and following treatment, when audiometry was performed. Late-onset depressed patients (LOD) had more hearing deficits compared to early-onset depressives (EOD). Age at onset of depression was found to have a significant effect on Pure-Tone Thresholds for 0.5-4.0 kHz and on Word Recognition in Noise in the better ear (0.001 < p < 0.031; ANCOVA). Criteria for neural deficit were met more frequently in LODs compared to EODs, although this was attributable to the older age of LOD. Additional investigations can contribute to our understanding of the relationship between forms of hearing loss and both the course of geriatric depression and its relationship to dementia.
authors.affiliation: Department of Psychiatry, Cornell University Medical College, New York, NY.
authors.forename: B
authors.initials: B
authors.lastname: Kalayam
authors.forename: B S
authors.initials: BS
authors.lastname: Meyers
authors.forename: T
authors.initials: T
authors.lastname: Kakuma
authors.forename: G S
authors.initials: GS
authors.lastname: Alexopoulos
authors.forename: R C
authors.initials: RC
authors.lastname: Young
authors.forename: S
authors.initials: S
authors.lastname: Solomon
authors.forename: R
authors.initials: R
authors.lastname: Shotland
authors.forename: D
authors.initials: D
authors.lastname: Nambudiri
authors.forename: D
authors.initials: D
authors.lastname: Goldsmith
mesh_terms: D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001299:Audiometry; D003702:Delusions / Q000175:diagnosis / Q000209:etiology; D003704:Dementia / Q000150:complications; D003866:Depressive Disorder / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D011304:Presbycusis / Q000150:complications / Q000175:diagnosis; D012044:Regression Analysis