title: A hepatitis B vaccination program targeting adolescents.
abstract: OBJECTIVE
  To determine the effectiveness of using a middle school for hepatitis B vaccination of adolescents.
  
  
  METHODS
  An immunization program was designed to educate parents and students about hepatitis B virus (HBV) infection and hepatitis B vaccination using science class presentations and mailings. Students were given at each visit and on vaccination series completion. Costs were calculated and divided by the number of students completing the series to obtain per student cost.
  
  
  RESULTS
  Of the 654 students, 519 (79%) received at least one dose of hepatitis B vaccine, 497 (76%) two doses, and 425 (65%) three doses. Student participation did not vary by grade level, gender, or income. Per student vaccination cost was $77.23 for those receiving three doses of hepatitis B vaccine and $66.04 when those receiving at least two doses were included. Of 103 students with postvaccination serologic testing, three had evidence of previous hepatitis B virus infection, four had no evidence of vaccine induced immunity, and 96 (96% of susceptible students) developed protective levels of antibodies against hepatitis B surface antigen. The geometric mean antibody titer among persons responding to vaccination was 661 mIU.
  
  
  CONCLUSIONS
  Hepatitis B vaccination of adolescents can be successfully integrated into a middle school setting.
authors.affiliation: Louisiana State University School of Medicine, Earl K. Long Medical Center, Baton Rouge, Louisiana, USA.
authors.forename: W M
authors.initials: WM
authors.lastname: Cassidy
authors.forename: F J
authors.initials: FJ
authors.lastname: Mahoney
mesh_terms: D000293:Adolescent; D016497:Adolescent Health Services / Q000458:organization & administration*; D002648:Child; D005240:Feasibility Studies; D005260:Female; D017048:Health Care Costs; D006266:Health Education; D006509:Hepatitis B / Q000517:prevention & control*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage* / Q000191:economics; D006801:Humans; D008297:Male; D015397:Program Evaluation; D012572:School Health Services / Q000458:organization & administration*; D014611:Vaccination / Q000191:economics / Q000379:methods
chemical_list: D017325:Hepatitis B Vaccines