title: A three-component model for magnetization transfer. Solution by projection-operator technique, and application to cartilage.
abstract: A projection-operator technique is applied to a general three-component model for magnetization transfer, extending our previous two-component model [R.S. Adler and H.N. Yeung, J. Magn. Reson. A 104, 321 (1993), and H.N. Yeung, R. S. Adler, and S.D. Swanson, J. Magn. Reson. A 106, 37 (1994)]. The PO technique provides an elegant means of deriving a simple, effective rate equation in which there is natural separation of relaxation and source terms and allows incorporation of Redfield-Provotorov theory without any additional assumptions or restrictive conditions. The PO technique is extended to incorporate more general, multicomponent models. The three-component model is used to fit experimental data from samples of human hyaline cartilage and fibrocartilage. The fits of the three-component model are compared to the fits of the two-component model.
authors.affiliation: Department of Radiology, University of Michigan Hospital, Ann Arbor 48109-0553, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Adler
authors.forename: S D
authors.initials: SD
authors.lastname: Swanson
authors.forename: H N
authors.initials: HN
authors.lastname: Yeung
mesh_terms: D000328:Adult; D000465:Algorithms; D001834:Body Water / Q000737:chemistry; D002356:Cartilage / Q000033:anatomy & histology* / Q000737:chemistry; D002358:Cartilage, Articular / Q000033:anatomy & histology / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D006818:Hyalin / Q000737:chemistry; D046911:Macromolecular Substances; D008279:Magnetic Resonance Imaging; D008297:Male; D008962:Models, Theoretical
chemical_list: D046911:Macromolecular Substances