The immunorejection of neoplasia in a theoretical model.
A theoretical model is presented based on the idea that the immune system of a patient with a tumour can cross-react against transplanted normal foreign cells as well as against the patient's own neoplastic cells, thereby rejecting both. This hypothesis is shown in a diagram, the potential use of which is discussed.
Pellettieri
L
L
Department of Neurosurgery, University Hospital, Uppsala, Sweden.
D000951:Antigens, Neoplasm / Q000276:immunology; D017690:Cell Transplantation; D003429:Cross Reactions; D006084:Graft Rejection / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology; D006648:Histocompatibility; D006789:Host vs Graft Reaction; D006801:Humans; D018448:Models, Immunological; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy; D014181:Transplantation Immunology; D014184:Transplantation, Homologous / Q000276:immunology
D000951:Antigens, Neoplasm; D006680:HLA Antigens