title: [Influence of liver cirrhosis with and without ascites on ventilatory mechanics].
abstract: BACKGROUND
  The thoracic cavity plays an important role in the mechanical ventilatory function, and the alteration of some of its structures, such as those which occur in decompensated cirrhosis of the liver, for example the presence of ascites and muscle atrophy, directly influence its normal function.
  
  
  METHODS
  In the present study we have evaluated the ventilatory function and respiratory muscular tension by means of the calculation of volumes, flows and resistances of the airways, and also the maximum inspiratory and expiratory pressures (Pimax, Pemax).
  
  
  METHODS
  One hundred patients with liver cirrhosis and ascites without associated respiratory illness, mean age 57 +/- 15 years (range 32-80), were studied. We evaluated the respiratory function before and after the disappearance of the ascites.
  
  
  RESULTS
  A restrictive pattern was evident, and various parameters were altered. The most affected being that of the reserve expiratory volume. No associated bronchial obstruction was observed. Respiratory muscular tension was decreased in both the Pimax and the Pemax. With the disappearance of the ascites we found an improvement in the affected parameters, but this did not reach normality.
  
  
  CONCLUSIONS
  In liver cirrhosis associated with ascites, the most common respiratory pattern, is a decrease in ventilatory function of a restrictive type, and also a decrease in the respiratory muscular tension. These alterations improve after the resolution of the ascites.
authors.affiliation: Sección de Neumología, Complejo Hospitalario de León.
authors.forename: J J
authors.initials: JJ
authors.lastname: Ordiales Fernández
authors.forename: A
authors.initials: A
authors.lastname: Fernández Moya
authors.forename: F
authors.initials: F
authors.lastname: Nistal de Paz
authors.forename: A
authors.initials: A
authors.lastname: Linares Rodríguez
authors.forename: L
authors.initials: L
authors.lastname: Colubi Colubi
authors.forename: E
authors.initials: E
authors.lastname: Alvarez Asensio
authors.forename: L
authors.initials: L
authors.lastname: Rodrigo Sáez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001201:Ascites / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000502:physiology* / Q000503:physiopathology
vernacular_title: Influencia de la cirrosis hepática con y sin ascitis sobre la mecánica ventilatoria.