[Nuclear receptors and ontogenesis of the hematopoietic tissue].
Differentiation of the hematopoietic tissue is controlled by growth factors which act precisely on stem cells arriving at a specific stage of differentiation. The recent identification of retinoic acid, a vitamin A metabolite, as an active differentiating agent of acute promyelocytic leukemia, has allowed to define a normal group of growth and differentiation factors of the myeloid tissue: vitamins A and B and thyroid hormones.
Chomienne
C
C
Laboratoire de Biologie Cellulaire Hématopoïétique, Hôpital Saint-Louis, Paris.
Guidez
F
F
Micléa
J M
JM
Bastie
J N
JN
Delva
L
L
Rousselot
P
P
Ballerini
P
P
D002454:Cell Differentiation / Q000187:drug effects; D002762:Cholecalciferol / Q000494:pharmacology; D004626:Embryology; D018922:HL-60 Cells / Q000473:pathology; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D007641:Keratolytic Agents / Q000494:pharmacology; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics*; D011988:Receptors, Thyroid Hormone / Q000235:genetics; D014212:Tretinoin / Q000494:pharmacology
D007641:Keratolytic Agents; D018160:Receptors, Cytoplasmic and Nuclear; D011988:Receptors, Thyroid Hormone; D002762:Cholecalciferol; D014212:Tretinoin
Récepteurs nucléaires et ontogénèse du tissu hématopoïétique.