title: Iron overload: prevalence and impact on health.
abstract: Clinical manifestations attributable to the damaging effects of iron occur when the total body iron is 5-10 times higher than normal. In adults this degree of iron overload occurs in hereditary hemochromatosis, a human leukocyte antigen (HLA)-linked autosomal recessive disorder, as well as in secondary iron-overload conditions.
authors.affiliation: Hematology/Oncology VAMC, Hampton, Virginia, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Lynch
mesh_terms: D000328:Adult; D005260:Female; D005808:Genes, Recessive; D006432:Hemochromatosis / Q000097:blood* / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007501:Iron / Q000097:blood* / Q000506:poisoning; D008297:Male; D008875:Middle Aged; D014481:United States
chemical_list: D007501:Iron