title: Mal de Meleda.
abstract: A case of mal de Meleda originating in Chile is reported. The patient had no history of consanguinity and cases could not be detected in four generations of the patient's family. The palmoplantar keratoderma was progrediens and transgrediens, with distant hyperkeratotic plaques of the knees and elbows. The nails, hair, and teeth were normal.
authors.affiliation: Caja de Previsión de la Defensa Nacional, Santiago, Chile.
authors.forename: F
authors.initials: F
authors.lastname: Urbina
authors.forename: M C
authors.initials: MC
authors.lastname: Cristóbal
authors.forename: R
authors.initials: R
authors.lastname: Sandoval
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D002677:Chile; D002908:Chronic Disease; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D008297:Male; D012008:Recurrence; D012867:Skin / Q000473:pathology / Q000648:ultrastructure*