title: Conservative management of ovarian hyperstimulation syndrome.
abstract: OBJECTIVE
  To evaluate the performance of a conservative treatment protocol for ovarian hyperstimulation syndrome (OHSS) that utilized low-dose dopamine, volume expanders and diuretics.
  
  
  METHODS
  Prospective, open trial.
  
  
  RESULTS
  Thirteen patients met the criteria for diagnosis of severe OHSS during the study period. Two of these were in vitro fertilization (IVF) patients who did not undergo transfer and so were excluded from analysis. Of the remaining 11, 10 (91%) were pregnant. The average time for resolution of the OHSS and discharge from the hospital was 6 days (range, 2-11). Compared to levels at admission, there was no significant difference in those of sodium, potassium or creatinine after resolution of the syndrome. Hemoglobin and hematocrit, however, were significantly reduced (P < .03). There were no cases of adult respiratory distress syndrome or thrombosis. No pregnancies were interrupted.
  
  
  CONCLUSIONS
  Conservative treatment of OHSS is an acceptable form of management. Risky and invasive therapies, such as paracentesis, are not warranted.
authors.affiliation: Department of Obstetrics and Gynecology, Lutheran General Hospital, Park Ridge, Illinois, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Morris
authors.forename: C
authors.initials: C
authors.lastname: Miller
authors.forename: L
authors.initials: L
authors.lastname: Jacobs
authors.forename: K
authors.initials: K
authors.lastname: Miller
mesh_terms: D000328:Adult; D004232:Diuretics / Q000627:therapeutic use*; D004298:Dopamine / Q000627:therapeutic use*; D016903:Drug Monitoring; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007902:Length of Stay; D016471:Ovarian Hyperstimulation Syndrome / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D010062:Ovulation Induction / Q000009:adverse effects; D010952:Plasma Substitutes / Q000627:therapeutic use*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies
chemical_list: D004232:Diuretics; D010952:Plasma Substitutes; D004298:Dopamine