title: Hypertrophic cranial pachymeningitis with spinal epidural granulomatous lesion.
abstract: A 67-year-old woman with a one-year history of tinnitus and headache had multiple cranial nerve palsies of V, VII, VIII, IX, X, XI and spastic paraparesis. She also had a secretory otitis media. Gd-DTPA-enhanced magnetic resonance imaging (MRI) revealed hypertrophy of the dura of the posterior fossa and spinal epidural mass which extended from C7 to T10. A biopsy of the epidural mass showed chronic granulomatous change. These lesions were completely cured with administration of antibiotics. We believe this case of double-lesion of hypertrophic cranial pachymeningitis and spinal epidural granulomatous lesion originated from a bacterial infection secondary to the secretory otitis media.
authors.affiliation: Department of Neurology, University of Tsukuba, Ibaraki.
authors.forename: M
authors.initials: M
authors.lastname: Adachi
authors.forename: A
authors.initials: A
authors.lastname: Hayashi
authors.forename: N
authors.initials: N
authors.lastname: Ohkoshi
authors.forename: H
authors.initials: H
authors.lastname: Nagata
authors.forename: H
authors.initials: H
authors.lastname: Mizusawa
authors.forename: S
authors.initials: S
authors.lastname: Shoji
authors.forename: F
authors.initials: F
authors.lastname: Tabei
authors.forename: A
authors.initials: A
authors.lastname: Matsumura
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D016920:Meningitis, Bacterial / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D010034:Otitis Media with Effusion / Q000150:complications / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents