High levels of aggrecan aggregate components are present in synovial fluids from human knee joints with chronic injury or osteoarthrosis.
Ratcliffe
A
A
Department of Orthopaedic Surgery, Columbia University, Columbia Presbyterian Medical Center, New York, NY 10032, USA.
Grelsamer
R P
RP
Kiernan
H
H
Saed-Nejad
F
F
Visco
D
D
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D053674:Aggrecans; D001182:Arthroscopy; D015415:Biomarkers / Q000032:analysis; D002358:Cartilage, Articular / Q000737:chemistry; D011508:Chondroitin Sulfate Proteoglycans / Q000032:analysis*; D002908:Chronic Disease; D018604:Epitope Mapping; D016326:Extracellular Matrix Proteins; D006801:Humans; D066298:In Vitro Techniques; D007718:Knee Injuries / Q000175:diagnosis*; D007719:Knee Joint / Q000737:chemistry; D037181:Lectins, C-Type; D008592:Menisci, Tibial / Q000737:chemistry; D008875:Middle Aged; D010003:Osteoarthritis / Q000175:diagnosis*; D011509:Proteoglycans / Q000032:analysis*; D013582:Synovial Fluid / Q000737:chemistry*
D053674:Aggrecans; D015415:Biomarkers; D011508:Chondroitin Sulfate Proteoglycans; D016326:Extracellular Matrix Proteins; D037181:Lectins, C-Type; D011509:Proteoglycans