title: Desmoid tumor occurring after reconstruction mammaplasty for breast carcinoma.
abstract: We present a case of desmoid tumor associated with prior alloplastic breast reconstruction. Wide local excision that includes chest wall resection, if necessary, is the primary treatment of choice. Patients with extensive nonresectable or recurrent disease may benefit from radiation therapy. Systemic therapy is a possibility in certain cases, but its toxicity generally precludes its use with this nonmetastatic tumor. Although this is the fourth reported case of desmoid tumor arising after implantation of a silicone prosthesis, we cannot claim a causal relationship. Careful follow-up consisting of yearly physical and mammagraphic examinations may facilitate early diagnosis and treatment of locally aggressive desmoid tumors but is not warranted, except in the context of routine screening for breast carcinoma.
authors.affiliation: Joyce Eisenberg Keefer Breast Center, John Wayne Cancer Institute at Saint John's Hospital and Health Center, Santa Monica, CA 90404, USA.
authors.forename: P S
authors.initials: PS
authors.lastname: Dale
authors.forename: J C
authors.initials: JC
authors.lastname: Wardlaw
authors.forename: D G
authors.initials: DG
authors.lastname: Wootton
authors.forename: J I
authors.initials: JI
authors.lastname: Resnick
authors.forename: A E
authors.initials: AE
authors.lastname: Giuliano
mesh_terms: D000368:Aged; D018427:Breast Implants / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000601:surgery*; D002278:Carcinoma in Situ / Q000601:surgery; D018275:Carcinoma, Lobular / Q000601:surgery; D005260:Female; D018222:Desmoid Tumors / Q000209:etiology*; D006801:Humans; D016462:Mammaplasty; D013899:Thoracic Neoplasms / Q000209:etiology