title: Expression of an ovine growth hormone transgene in mice causes organomegaly and hepatic lesions which resolve following transgene inactivation.
authors.affiliation: Animal Resources Service, University of California at Davis 95616, USA.
authors.forename: K R
authors.initials: KR
authors.lastname: Sharp
authors.forename: D E
authors.initials: DE
authors.lastname: Knudsen
authors.forename: D
authors.initials: D
authors.lastname: Pomp
authors.forename: J D
authors.initials: JD
authors.lastname: Murray
mesh_terms: D000818:Animals; D001835:Body Weight; D048429:Cell Size; D005260:Female; D005786:Gene Expression Regulation / Q000235:genetics; D013006:Growth Hormone / Q000096:biosynthesis / Q000235:genetics*; D006529:Hepatomegaly / Q000473:pathology / Q000662:veterinary; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D008297:Male; D051379:Mice; D008822:Mice, Transgenic / Q000235:genetics*; D009929:Organ Size; D011247:Pregnancy; D012376:Rodent Diseases / Q000209:etiology* / Q000473:pathology; D012756:Sheep / Q000235:genetics; D013163:Splenomegaly / Q000473:pathology / Q000662:veterinary; D019076:Transgenes / Q000235:genetics*
chemical_list: D013006:Growth Hormone