title: [C-reactive protein: structure, properties, and methods of isolation].
abstract: Data on the structure, properties, and biosynthesis of C-reactive protein (CRP) are summarized. Special attention is paid to the specific interaction of C-reactive protein with Ca(2+)-dependent and Ca(2+)-independent ligands: phosphorylcholine-containing compounds, lipoproteins, chromatin, galactans, polycations, etc. The data on the interaction of CRP with Ca2+ are presented. The methods for the CRP isolation and purification are discussed with an emphasis on affinity chromatography as the most promising method for obtaining purified CRP.
authors.forename: E G
authors.initials: EG
authors.lastname: Zotova
authors.forename: E B
authors.initials: EB
authors.lastname: Mysiakin
authors.forename: S Zh
authors.initials: SZh
authors.lastname: Toksambaeva
authors.forename: K S
authors.initials: KS
authors.lastname: Rubtsov
authors.forename: G A
authors.initials: GA
authors.lastname: Serebrennikova
mesh_terms: D000595:Amino Acid Sequence; D002097:C-Reactive Protein / Q000096:biosynthesis / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002846:Chromatography, Affinity; D006801:Humans; D008024:Ligands; D008969:Molecular Sequence Data; D011485:Protein Binding
chemical_list: D008024:Ligands; D002097:C-Reactive Protein; D002118:Calcium
vernacular_title: C-reaktivnyĭ belok: stroenie, svoĭstva i sposoby ego vydeleniia.