title: Primary hypergammaglobulinemic purpura associated with IgG2 deficiency. A case report.
abstract: Hypergammaglobulinemic purpura is a rare disease in children. We report a case of a 12 year-old girl with a history of frequent infections. We found the presence of IgG2 deficiency despite polyclonal hypergammaglobulinemia. An IgG subclass determination should be obtained in every child with polyclonal hypergammaglobulinemia and features of immunodeficiency.
authors.affiliation: Dipartimento di Scienze Ostetriche, Ginecologiche e Pediatriche, Università di Modena, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Venuta
authors.forename: R
authors.initials: R
authors.lastname: Penza
authors.forename: M
authors.initials: M
authors.lastname: Cellini
authors.forename: E
authors.initials: E
authors.lastname: Garetti
authors.forename: A
authors.initials: A
authors.lastname: Bergomi
authors.forename: S
authors.initials: S
authors.lastname: Pastorelli
authors.forename: F
authors.initials: F
authors.lastname: Massolo
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications* / Q000276:immunology; D017099:IgG Deficiency / Q000150:complications* / Q000276:immunology; D007074:Immunoglobulin G / Q000097:blood*; D011694:Purpura, Hyperglobulinemic / Q000150:complications* / Q000276:immunology
chemical_list: D007074:Immunoglobulin G