title: [The assessment of solitary osteolytic bone lesions in breast carcinoma. A special case report].
abstract: BACKGROUND
  Solitary bone lesions occurring 10 and more years after primary known breast cancer are usually declared as metastases of this tumor. However, this assumption is not correct. In such cases the probability of a second malignancy has to be concerned as well.
  
  
  METHODS
  We report the case of a 77-year-old woman, in whom 18 years after primary breast cancer therapy an osteolysis in her right radius occurred. The treatment planning was aggravated by the diagnostic classification of this lesion.
  
  
  RESULTS
  The diagnostical differentiation between bone metastases of the known breast cancer or another extramammary solid cancer and a primary tumor of the bone was not possible by clinical and blood examination, X-ray and MRT-imaging. As the diagnostically decisive step a biopsy was performed proving a metastasis of the known breast cancer.
  
  
  CONCLUSIONS
  This case pointed out that the diagnostical classification of a solitary osseous lesion exclusively based on anamnestically known primary cancer treated long times ago is not permissible. Before therapeutic decision is correctly fixed, detailed diagnostic examinations according to basic oncological rules are conclusively required.
authors.affiliation: Abteilung für Strahlentherapie und Onkologie, Johann-Wolfgang-Goethe-Universität Frankfurt am Main.
authors.forename: S
authors.initials: S
authors.lastname: Mose
authors.forename: I A
authors.initials: IA
authors.lastname: Adamietz
authors.forename: H D
authors.initials: HD
authors.lastname: Böttcher
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary; D001943:Breast Neoplasms / Q000150:complications* / Q000175:diagnosis; D018276:Carcinoma, Medullary / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary; D010014:Osteolysis / Q000175:diagnosis / Q000209:etiology*; D011859:Radiography; D011884:Radius / Q000000981:diagnostic imaging; D013997:Time Factors
vernacular_title: Zur Dignität solitärer osteolytischer Knochenläsionen beim Mammakarzinom. Einzelfallbericht.