title: Lipid peroxidation in cord blood at birth.
abstract: OBJECTIVE
  The purpose of this study was to determine oxygen free radical activity in the neonate at birth and relate it to umbilical cord blood acid-base status.
  
  
  METHODS
  A series of 110 singleton deliveries had determination of two lipoperoxides in umbilical cord blood: malondialdehyde and organic hydroperoxide. Umbilical pH, PO2, PCO2, bicarbonate, and base excess were also measured.
  
  
  RESULTS
  There was a significant association between lipoperoxides and cord blood pH and base excess. A significant difference existed in the levels of umbilical artery lipoperoxides between nonacidemic and acidemic fetus, as defined by an umbilical arterial pH < 7.20.
  
  
  CONCLUSIONS
  There is a positive association between lipoperoxide production and acid-base balance at delivery.
authors.affiliation: Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
authors.forename: W
authors.initials: W
authors.lastname: Wang
authors.forename: C C
authors.initials: CC
authors.lastname: Pang
authors.forename: M S
authors.initials: MS
authors.lastname: Rogers
authors.forename: A M
authors.initials: AM
authors.lastname: Chang
mesh_terms: D000136:Acid-Base Equilibrium; D000293:Adolescent; D000328:Adult; D002245:Carbon Dioxide / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood; D006863:Hydrogen-Ion Concentration; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood; D010100:Oxygen / Q000097:blood; D011247:Pregnancy
chemical_list: D002245:Carbon Dioxide; D008315:Malondialdehyde; D006861:Hydrogen Peroxide; D010100:Oxygen