Responses of neurons in the caudal intralaminar thalamic complex of the rat to stimulation of the uterus, vagina, cervix, colon and skin.
This study examined responses of 35 neurons in the caudal intralaminar (IL) thalamic nuclei in 12 adult female virgin rats to mechanical stimulation of the skin (brush, pressure, pinch) and to 4 different visceral stimuli (noxious distension of the uterine horns and vaginal canal; gentle distension of the colon and probing the cervix). As in male rats and other species, many IL neurons (24/35) responded to frankly noxious somatic stimuli applied to several bodily regions. Some of these (16/24) also responded to one or more of the visceral stimuli (mainly the noxious ones), while 4/35 responded only to a visceral stimulus. Thus, unlike neurons in lateral thalamus studied under identical conditions, IL neurons appear to be signalling information primarily when intense somatic and visceral stimuli are frankly above the noxious threshold.
Berkley
K J
KJ
Program in Neuroscience, Florida State University, Tallahassee 32306-1051, USA.
Benoist
J M
JM
Gautron
M
M
Guilbaud
G
G
D000818:Animals; D002584:Cervix Uteri / Q000502:physiology; D003106:Colon / Q000502:physiology; D005260:Female; D009474:Neurons / Q000502:physiology*; D010812:Physical Stimulation; D051381:Rats; D012879:Skin Physiological Phenomena; D013788:Thalamus / Q000502:physiology*; D014599:Uterus / Q000502:physiology*; D014621:Vagina / Q000502:physiology*