title: Application of a new atmospheric pressure ionization source for double focusing sector instruments.
abstract: In three application examples we demonstrate how the capabilities of a modern atmospheric pressure ionization (API) source, as a universal LC-MS coupling tool, are supplemented by the high mass resolution available on double focusing sector instruments. The examples include charge state determination in complex electrospray ionization-collisional induced dissociation (ESI-CID) spectra of multiply charged ions, mixture analysis of multicomponent samples without prior chromatographic separation, and very sensitive and highly specific detection of pesticides using atmospheric pressure chemical ionization (APCI).
authors.affiliation: Finnigan MAT, Bremen, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Dobbertein
authors.forename: H
authors.initials: H
authors.lastname: Muenster
mesh_terms: D000595:Amino Acid Sequence; D001274:Atmospheric Pressure; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007477:Ions; D013058:Mass Spectrometry / Q000379:methods*; D008969:Molecular Sequence Data; D010575:Pesticides / Q000032:analysis; D017421:Sequence Analysis
chemical_list: D007477:Ions; D010575:Pesticides