title: [Fetal fibronectin diagnosis of premature rupture of the amniotic membranes].
abstract: OBJECTIVE
  To determine whether fetal fibronectin is a sensitive test for the detection of premature rupture of the amniotic membranes.
  
  
  METHODS
  Fetal fibronectin by ABC immunoblotting methods were measured in samples of cervicovaginal secretion from 80 cases with ruptured amniotic membranes (study group) and 50 cases of term pregnancy (control group A). Plasma fetal fibronectin were examined in 30 cases of normal pregnancy (control group B).
  
  
  RESULTS
  The detection rate of fetal fibronectin in the women with ruptured membranes was 95.0%, While 6% in normal pregnancy.
  
  
  CONCLUSIONS
  Fetal fibronectin is a sensitive test for detection of present of amniotic fluid. It can be used for diagnosis of ruptured amniotic membranes.
authors.affiliation: Changhai Hospital, Second Military Medical University, Shanghai.
authors.forename: H
authors.initials: H
authors.lastname: Gu
authors.forename: Y
authors.initials: Y
authors.lastname: Ding
authors.forename: Y
authors.initials: Y
authors.lastname: Li
mesh_terms: D000653:Amniotic Fluid / Q000737:chemistry; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000175:diagnosis*; D005353:Fibronectins / Q000032:analysis*; D006801:Humans; D015151:Immunoblotting; D011247:Pregnancy; D014626:Vaginal Smears
chemical_list: D005353:Fibronectins