General linear compartment model with zero input: I. Kinetic equations.
The derivation of kinetic equations is described for n-compartment linear models, in which the substance may be simultaneously introduced into one or more compartments at t = 0 and eliminated from any compartment. For a given zero-input, general formulas are derived which describe the amount of tracer in any of the compartments as a function of time and the model parameters. New algorithms have been developed which allow the expression of the kinetic equations.
Varón
R
R
Departamento de Química-Fisica, Universidad de Castilla-La Mancha, Albacete, Spain.
García-Meseguer
M J
MJ
García-Cánovas
F
F
Havsteen
B
B
D000465:Algorithms; D003198:Computer Simulation; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D016014:Linear Models
D004798:Enzymes