title: Oxidants and antioxidants in exercise.
abstract: There is consistent evidence from human and animal studies that strenuous physical exercise may induce a state wherein the antioxidant defenses of several tissues are overwhelmed by excess reactive oxygen. A wide variety of physiological and dietary antioxidants act in concert to evade such a stress. Submaximal long-duration exercise training may augment the physiological antioxidant defenses in several tissues; however, this enhanced protection may not be sufficient to completely protect highly fit individuals from exhaustive exercise-induced oxidative stress. Regular physical activity in association with dietary habits that ensure adequate supply of a combination of appropriate antioxidants may be expected to yield desirable results. The significance of this area of research, current state of information, and possibilities of further investigation are briefly reviewed.
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley 94720-3200, USA.
authors.forename: C K
authors.initials: CK
authors.lastname: Sen
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D018482:Muscle, Skeletal / Q000378:metabolism*; D016877:Oxidants / Q000378:metabolism*; D010805:Physical Conditioning, Animal / Q000502:physiology
chemical_list: D000975:Antioxidants; D016877:Oxidants