title: The effect of temperature on the stability of the synthetic SPf(66)n malaria vaccine.
abstract: We hereby report on the effect of temperature on the physico-chemical and immunogenic characteristics and stability of the SPf(66)n synthetic malaria vaccine. The pattern of polymerization, the adsorption to aluminium hydroxide and the immunological properties of these vaccine groups were not significantly affected.
authors.affiliation: Instituto de Parasitologia y Biomedicina López Neyra, CSIC, Granada, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: López
authors.forename: M C
authors.initials: MC
authors.lastname: Thomas
authors.forename: M
authors.initials: M
authors.lastname: Olivares
authors.forename: P
authors.initials: P
authors.lastname: Alonso
authors.forename: C
authors.initials: C
authors.lastname: Alonso
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000953:Antigens, Protozoan; D003906:Developing Countries; D004355:Drug Stability; D006801:Humans; D017780:Malaria Vaccines / Q000737:chemistry*; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000276:immunology*; D011634:Public Health; D013696:Temperature; D014614:Vaccines, Synthetic / Q000737:chemistry*
chemical_list: D000953:Antigens, Protozoan; D017780:Malaria Vaccines; D014614:Vaccines, Synthetic