title: General linear compartment model with zero input: III. First passage residence time of enzyme systems.
abstract: In this paper, we present an alternative procedure to derive the residence times of enzyme and compartment systems. This procedure allows to express the residence time by a general, symbolic and simplified formula relating it directly with the rate constants. It is applicable to any enzyme reaction scheme which can be formulated as a set of first-order or pseudo-first order interconversions, without any other restriction. A computer program has been developed that greatly facilitates the task of the residence time derivations. The above analysis was extrapolated to any linear compartment model.
authors.affiliation: Departamento de Química-Fisica, Universidad de Castilla-La Mancha, Albacete, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Varón
authors.forename: M J
authors.initials: MJ
authors.lastname: García-Meseguer
authors.forename: E
authors.initials: E
authors.lastname: Valero
authors.forename: M
authors.initials: M
authors.lastname: García-Moreno
authors.forename: F
authors.initials: F
authors.lastname: García-Cánovas
mesh_terms: D003198:Computer Simulation; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D016014:Linear Models; D012984:Software
chemical_list: D004798:Enzymes