Follicular thyroid carcinoma and mediastinal goiter in a case of situs inversus viscerum.
A 55-year-old woman with total situs inversus viscerum was subjected to total thyroidectomy for a well-differentiated follicular thyroid carcinoma. After surgery the patient remained euthyroid for two months and serum TSH did not rise. A whole body scan with iodine-131 (131I) showed mediastinal uptake. A chest computed tomography visualized a sequestered substernal goiter. Upon the patient's refusal to undergo surgery, she was treated with 150 mCi of 131I. A further dose of 100 mCi of 131I was administered six months later. Ten years after treatment, the patient is still alive and disease-free.
Panza
N
N
Unit of Immunological and Endocrinological Oncology, Cardarelli Hospital, Naples, Italy.
Mansi
L
L
Pacilio
C
C
Lombardi
G
G
D018263:Adenocarcinoma, Follicular / Q000097:blood / Q000150:complications* / Q000601:surgery; D005260:Female; D006045:Goiter, Substernal / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D007457:Iodine Radioisotopes; D008875:Middle Aged; D011877:Radionuclide Imaging; D012857:Situs Inversus / Q000150:complications*; D013954:Thyroglobulin / Q000097:blood; D013964:Thyroid Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000601:surgery; D013965:Thyroidectomy; D013972:Thyrotropin / Q000097:blood; D014057:Tomography, X-Ray Computed
D007457:Iodine Radioisotopes; D013972:Thyrotropin; D013954:Thyroglobulin