title: Anti-inflammatory effects of tianrong acupoint on blood vessels of dura mater.
abstract: Although Tianrong acupoint (SI 17) is used for migraine headache, its mechanism of action remains obscure. The effects of Tianrong acupoint therapy on neurogenically-mediated plasma protein extravasation (125I-BSA) in rat dura mater induced by electrical stimulation of the right trigeminal ganglion was studied. When the unilateral trigeminal ganglion was stimulated (5 Hz, 1.2 mA, 5 msec for 5 min), the ratio of stimulated side/unstimulated side (cpm/mg) was 1.6663 +/- 0.0217. The plasma extravasation was blocked by different kinds of treatment in different degrees. The order of the ratio was as follow: Tianrong acupoint therapy (1.0917 +/- 0.0266) and Tianrong electrical needle therapy (1.1281 +/- 0.0227) < Tianrong acupoint injection with normal saline (1.325 +/- 0.0444) < Quchi acupoint (LI 11) injection with prednisolonum (1.5284 +/- 1.1624). The results indicated that Tianrong acupoint therapy could inhibit the neurongenic inflammation on the affected side.
authors.affiliation: Dept. of Neurology, Chinese PLA General Hospital, Postgraduate Medical School, Beijing, China.
authors.forename: S
authors.initials: S
authors.lastname: Yu
authors.forename: P
authors.initials: P
authors.lastname: Kuang
authors.forename: F
authors.initials: F
authors.lastname: Zhang
authors.forename: J
authors.initials: J
authors.lastname: Liu
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000818:Animals; D002199:Capillary Permeability; D004388:Dura Mater / Q000098:blood supply; D015671:Electroacupuncture; D007249:Inflammation / Q000628:therapy*; D008297:Male; D008881:Migraine Disorders / Q000209:etiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012668:Trigeminal Ganglion / Q000502:physiology*