title: Automated lesion placement in the rabbit eye.
abstract: OBJECTIVE
  The objective of this research was to build a prototype feedback control system to precisely place argon laser lesions on the retina for treatment of retinal disorders. STUDY DESIGN/MATERIALS, AND METHODS: The prototype feedback control system was tested by placing lesions at specific locations on the retina of pigmented rabbits to simulate the treatment of diabetic retinopathy, retinal breaks or tears, and a pre-programmed, two-dimensional array of lesions was placed at a specific site.
  
  
  RESULTS
  Results of feedback-controlled lesion placement performed in vivo on pigmented rabbits are presented. The ability to place lesions with automated feedback control is demonstrated.
  
  
  CONCLUSIONS
  Automated feedback control placement of argon laser lesions is possible at a reasonable cost and has numerous therapeutic and safety benefits over current ballistic delivery.
authors.affiliation: Biomedical Engineering Program, University of Texas, Austin 78712, USA.
authors.forename: S F
authors.initials: SF
authors.lastname: Barrett
authors.forename: M R
authors.initials: MR
authors.lastname: Jerath
authors.forename: H G
authors.initials: HG
authors.lastname: Rylander
authors.forename: A J
authors.initials: AJ
authors.lastname: Welch
mesh_terms: D000818:Animals; D005246:Feedback; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008028:Light Coagulation / Q000295:instrumentation*; D011817:Rabbits; D012160:Retina / Q000473:pathology / Q000601:surgery*; D012164:Retinal Diseases / Q000473:pathology / Q000601:surgery; D012984:Software