title: Fatty liver-hemorrhagic syndrome observed in commercial layers fed diets containing chelated minerals.
abstract: This study was originally conducted to determine the effect of various chloride levels and consumption of chelated versus non-chelated minerals on egg production and eggshell breaking strength. However, the focus of this report changed after fatty liver-hemorrhagic syndrome (FLHS) was observed in hens that consumed diets containing chelated minerals. No FLHS was observed in hens that consumed a diet that contained non-chelated minerals. Four hundred thirty-two 35-week-old commercial laying hens were housed in individual cages in groups of nine hens each. The treatments were factorially arranged (3 x 2) such that six experimental diets differing in chloride levels and in source of minerals were fed for six 28-day laying periods. A significantly higher mortality attributed to FLHS was observed in hens that consumed the diets having chelated minerals as compared with hens that consumed the diets with non-chelated minerals. No difference in mortality was observed among the hens fed the various chloride diets.
authors.affiliation: USDA, South Central Poultry Research Laboratory, Mississippi State, Mississippi 39762, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Branton
authors.forename: B D
authors.initials: BD
authors.lastname: Lott
authors.forename: W R
authors.initials: WR
authors.lastname: Maslin
authors.forename: E J
authors.initials: EJ
authors.lastname: Day
mesh_terms: D000821:Animal Feed / Q000633:toxicity*; D000818:Animals; D002614:Chelating Agents / Q000633:toxicity*; D002645:Chickens; D005234:Fatty Liver / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D008099:Liver / Q000187:drug effects; D008903:Minerals / Q000633:toxicity*; D011201:Poultry Diseases / Q000139:chemically induced* / Q000473:pathology; D013577:Syndrome
chemical_list: D002614:Chelating Agents; D008903:Minerals