[The interferon status and cellular immunity of pregnant women with viral hepatitis B].
The examination of 62 pregnant women with acute viral hepatitis B has established in them inhibition of interferon genesis and the presence of secondary T-cell immunodeficiency. The most pronounced and long-lasting was a fall of gamma-interferon. A simultaneous lowering of alpha-, gamma- and serum interferon was indicative of complicated pregnancy or premorbid condition. A persistent deficient production of gamma-interferon and T lymphocytes, imbalance of their subpopulations promoted long-term course of hepatitis and persistence of HBsAg.
Akhmedova
M D
MD
Zmyzgova
A V
AV
Karimova
M T
MT
D000033:Abortion, Threatened / Q000276:immunology; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D003289:Convalescence; D005260:Female; D006509:Hepatitis B / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007372:Interferons / Q000097:blood*; D018655:Lymphocyte Count; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D007372:Interferons
Interferonovyĭ status i kletochnyĭ immunitet u beremennykh zhenshchin, bol'nykh ostrym virusnym gepatitom B.