title: Does pulmonary hypertension syndrome (ascites) occur more frequently in broilers medicated with monensin?
abstract: The performance of broilers reared in floor pens and given monensin in the feed at 121 ppm was compared with that of birds given no drug. Feed intake and BW gain of medicated birds was significantly lower than that of unmedicated birds from 0 to 22 d of age. Feed intake and feed conversion of medicated birds was significantly reduced, compared with unmedicated birds, from 22 to 53 and 0 to 60 d of age. Total mortality, and mortality due to leg abnormalities from 22 to 53 and 0 to 60 d, was significantly lower in birds given monensin. There was no difference in the incidence of tibial dyschondroplasia (TD) by 60 d. No differences in mortality due to pulmonary hypertension syndrome (PHS) were observed for any age period. Birds removed from pens at 28 d that had received monensin had lower hematocrit and percentage saturation of hemoglobin with oxygen in the blood than unmedicated birds. No differences in these variables were found at 54 d. There were no differences in the right ventricle weight: total ventricular weight ratios or electrocardiogram lead II values at 28 or 54 d. The results indicate that PHS does not occur more frequently in broilers medicated with monensin.
authors.affiliation: Department of Poultry Science, University of Arkansas, Fayetteville 72701, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Chapman
authors.forename: H D
authors.initials: HD
authors.lastname: Chapman
authors.forename: R F
authors.initials: RF
authors.lastname: Wideman
authors.forename: W E
authors.initials: WE
authors.lastname: Huff
authors.forename: A H
authors.initials: AH
authors.lastname: Hacker
authors.forename: N C
authors.initials: NC
authors.lastname: Rath
authors.forename: J M
authors.initials: JM
authors.lastname: Balog
mesh_terms: D000818:Animals; D001201:Ascites / Q000139:chemically induced / Q000453:epidemiology / Q000662:veterinary*; D002645:Chickens; D004435:Eating / Q000187:drug effects; D005527:Food, Fortified; D015994:Incidence; D008297:Male; D008985:Monensin / Q000008:administration & dosage*; D011201:Poultry Diseases / Q000139:chemically induced / Q000453:epidemiology*; D015430:Weight Gain / Q000187:drug effects
chemical_list: D008985:Monensin