title: Cholesterol granuloma in the middle cranial fossa: report of two cases.
abstract: We report two cases of cholesterol granuloma in the middle cranial fossa. On CT the lesions appeared as a nonspecific, nonenhancing soft-tissue mass with bone erosion. On MRI they were seen as areas of high signal intensity surrounded by a low-intensity peripheral zone on both T1- and T2-weighted images. Cholesterol granuloma is thought to occur when pneumatised cells in the temporal bone become obstructed. Although this lesion usually occurs in the petrous bone, it can extend to the middle cranial fossa. The diagnosis and surgical management are discussed.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Kyushu University 60, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Morioka
authors.forename: K
authors.initials: K
authors.lastname: Fujii
authors.forename: S
authors.initials: S
authors.lastname: Nishio
authors.forename: Y
authors.initials: Y
authors.lastname: Miyagi
authors.forename: S
authors.initials: S
authors.lastname: Nagata
authors.forename: K
authors.initials: K
authors.lastname: Hasuo
authors.forename: K
authors.initials: K
authors.lastname: Hisashi
authors.forename: M
authors.initials: M
authors.lastname: Fukui
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002784:Cholesterol; D003937:Diagnosis, Differential; D004427:Ear Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D004432:Ear, Middle / Q000473:pathology / Q000601:surgery; D005260:Female; D015745:Granuloma, Foreign-Body / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008416:Mastoid / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D010579:Petrous Bone / Q000473:pathology / Q000601:surgery; D013701:Temporal Bone / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D002784:Cholesterol