title: Treatment of migraine headache after ocular surgery with intravenous metoclopramide hydrochloride.
abstract: OBJECTIVE
  To alert ophthalmologists that prolonged or severe postoperative periocular pain and nausea may be caused by migraine.
  
  
  METHODS
  We examined two patients who had a history of migraine and had severe episodes of prolonged periocular pain and nausea after ocular procedures. Both patients experienced symptoms similar to their previous migraine attacks. In neither was pain alleviated by routine analgesics.
  
  
  RESULTS
  Each patient had relief of symptoms within two minutes after intravenous delivery of metoclopramide hydrochloride.
  
  
  CONCLUSIONS
  Ophthalmologists should consider the diagnosis of postoperative migraine in similar patients and provide specific therapy such as intravenous metoclopramide hydrochloride.
authors.affiliation: Duke University Eye Center, Durham, NC 27710, USA.
authors.forename: M W
authors.initials: MW
authors.lastname: MacCumber
authors.forename: G J
authors.initials: GJ
authors.lastname: Jaffe
authors.forename: B W
authors.initials: BW
authors.lastname: McCuen
mesh_terms: D000328:Adult; D002387:Cataract Extraction / Q000009:adverse effects*; D018492:Dopamine Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007910:Lenses, Intraocular; D008297:Male; D008787:Metoclopramide / Q000008:administration & dosage / Q000627:therapeutic use*; D008881:Migraine Disorders / Q000188:drug therapy* / Q000209:etiology; D009325:Nausea / Q000188:drug therapy / Q000209:etiology; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology; D012163:Retinal Detachment / Q000601:surgery; D012166:Retinal Hemorrhage / Q000601:surgery; D014821:Vitrectomy / Q000009:adverse effects*
chemical_list: D018492:Dopamine Antagonists; D008787:Metoclopramide