title: Distribution of serotypes of Streptococcus pneumoniae isolated from invasive infections over a 16-year period in the greater São Paulo area, Brazil.
abstract: Capsular types of pneumococci from normally sterile body sites of 1,622 patients in Brazil were analyzed. Of 1,477 isolates from cerebrospinal fluid, 76.1% were of types represented in the currently available pneumococcal vaccine. The importance of age, time, and place in determining the optimal formulation of pneumococcal vaccine is considered.
authors.affiliation: Bacteriology Division, Adolfo Lutz Institute, São Paulo, Brazil.
authors.forename: M C
authors.initials: MC
authors.lastname: Brandileone
authors.forename: V S
authors.initials: VS
authors.lastname: Vieira
authors.forename: R C
authors.initials: RC
authors.lastname: Zanella
authors.forename: I M
authors.initials: IM
authors.lastname: Landgraf
authors.forename: C E
authors.initials: CE
authors.lastname: Melles
authors.forename: A
authors.initials: A
authors.lastname: Taunay
authors.forename: J C
authors.initials: JC
authors.lastname: de Moraes
authors.forename: R
authors.initials: R
authors.lastname: Austrian
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001428:Bacterial Vaccines; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008586:Meningitis, Pneumococcal / Q000453:epidemiology / Q000382:microbiology; D008875:Middle Aged; D010995:Pleural Diseases / Q000382:microbiology; D011008:Pneumococcal Infections / Q000134:cerebrospinal fluid / Q000453:epidemiology / Q000382:microbiology*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification*
chemical_list: D001428:Bacterial Vaccines