title: Localized Langerhans cell histiocytosis of bone: treatment and follow- up in children.
abstract: We report a case of Langerhans cell histiocytosis (LCH) involving the right scapula in a 4-year-old child. Because of progressive shoulder pain and immobility methylprednisolone was injected directly into the lesion under computed tomography (CT) guidance. Follow-up studies with magnetic resonance imaging (MRI) and ultrasound (US) revealed continuous ossification of the osteolytic lesion with healing after 6 months. Plain films and CT confirmed the healing process. We consider intralesional corticoid instillation a safe method when performed under CT guidance. For initial evaluation and follow-up, MRI and US yielded reliable results in comparison to plain films and CT, thus helping to reduce the radiation dosage in children.
authors.affiliation: Department of Diagnostic Radiology, University of Heidelberg, Im Neuenheimer Feld 110, D-69120 Heidelberg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Libicher
authors.forename: T
authors.initials: T
authors.lastname: Roeren
authors.forename: J
authors.initials: J
authors.lastname: Tröger
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001847:Bone Diseases / Q000175:diagnosis / Q000188:drug therapy*; D002675:Child, Preschool; D003952:Diagnostic Imaging; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use*; D012540:Scapula; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D008775:Methylprednisolone