title: [Morphological and biological features of squamous cell carcinoma of the larynx].
abstract: The study of morphological and biological criteria of laryngeal squamous cell carcinoma in 81 patients proved essential in the disease prognosis. In grade I malignancy 90 +/- 6.7% of patients were 3 years free of recurrences and metastases, in grade 11 - 76 +/- 8.6%, in grade III - 50 +/- 15.8%. Aneuploid laryngeal tumors produced recurrences 6 times more frequently than diploid ones. 3-year recurrence--and metastases-free survival was reported in 88.7 +/- 6.3% of patients with diploid and 59.3 +/- 7.7%. 7% with aneuploid tumors (p < 0.05).
authors.forename: V S
authors.initials: VS
authors.lastname: Alferov
authors.forename: A A
authors.initials: AA
authors.lastname: Akhundov
authors.forename: A I
authors.initials: AI
authors.lastname: Pavlovskaia
authors.forename: T G
authors.initials: TG
authors.lastname: Nikolaeva
authors.forename: R I
authors.initials: RI
authors.lastname: Azizian
authors.forename: K M
authors.initials: KM
authors.lastname: Zak
authors.forename: L E
authors.initials: LE
authors.lastname: Rotobel'skaia
mesh_terms: D000328:Adult; D000368:Aged; D000782:Aneuploidy; D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000401:mortality / Q000473:pathology*; D004273:DNA, Neoplasm / Q000235:genetics; D004171:Diploidy; D018572:Disease-Free Survival; D006801:Humans; D007822:Laryngeal Neoplasms / Q000235:genetics* / Q000401:mortality / Q000473:pathology*; D007830:Larynx / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D013997:Time Factors
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Morfologicheskie i biologicheskie osobennosti ploskokletochnogo raka gortani.