Rocuronium with alfentanil and propofol allows intubation within 45 seconds.
Following induction with alfentanil (20 micrograms kg-1) and propofol (2.0-2.5 mg kg-1), four groups of patients were given rocuronium to determine conditions for rapid sequence intubation. Two groups received 0.9 mg kg-1 and two groups received 0.6 mg kg-1. In one of each dose groups, intubation was attempted after 45 s and in the other after 60 s. Intubating conditions were scored on a four point scale but all were rated as excellent or good. Almost all intubating conditions were excellent in the 0.9 mg kg-1 groups.
Crul
J F
JF
St Jans Hospital, Genk, Belgium.
Vanbelleghem
V
V
Buyse
L
L
Heylen
R
R
van Egmond
J
J
D000732:Androstanols; D000758:Anesthesia; D018686:Anesthetics, Intravenous; D006801:Humans; D007442:Intubation, Intratracheal; D003473:Neuromuscular Nondepolarizing Agents; D015742:Propofol; D012018:Reflex / Q000187:drug effects; D000077123:Rocuronium; D013997:Time Factors
D000732:Androstanols; D018686:Anesthetics, Intravenous; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium; D015742:Propofol