title: [Ultrastructural study of hereditary benign telangiectasia. Differential diagnosis from Osler Rendu disease].
abstract: BACKGROUND
  There are two hereditary forms of primary telangiectasia with a totally opposite prognosis. In Rendu-Osler disease, also called hereditary haemorrhagic telangiectasia, there is a major risk of severe haemorrhage in adults. In benign hereditary telangiectasia there is no such risk.
  
  
  METHODS
  We report two brothers who were diagnosed as having Rendu-Osler disease. Under standard electron microscopy, a biopsy of a telangiectasia taken from the right arm pit showed that the vessels of the superficial reticular derma were dilated with thick walls but no dehiscences as in Rendu-Osler disease.
  
  
  CONCLUSIONS
  This ultrastructure explains why there had been no haemorrhages in our two cases and favoured a diagnosis of hereditary benign telangiectasia.
authors.affiliation: Département d'Histologie, Faculté de Médecine Lariboisière-Saint-Louis, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Tsianakas
authors.forename: D
authors.initials: D
authors.lastname: Teillac-Hamel
authors.forename: S
authors.initials: S
authors.lastname: Fraitag
authors.forename: Y
authors.initials: Y
authors.lastname: De Prost
authors.forename: C
authors.initials: C
authors.lastname: Prost
mesh_terms: D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D011379:Prognosis; D012867:Skin / Q000648:ultrastructure*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000175:diagnosis*; D013684:Telangiectasis / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology
vernacular_title: Etude ultrastructurale des télangiectasies héréditaires bénignes. Un diagnostic différentiel de la maladie de Rendu-Osler.