Towards molecular oncology.
Oncogene amplification and loss of heterozygosity for tumor suppressor genes have been correlated with prognosis in a variety of human tumors. Detection of mutations in tumor suppressor genes have been found to serve as risk factor determinants in gastrointestinal adenocarcinomas.
Brentani
R R
RR
Department of Oncologic and Radiologic, University of São Paulo.
Brentani
M M
MM
D000230:Adenocarcinoma / Q000235:genetics*; D005770:Gastrointestinal Neoplasms / Q000235:genetics*; D016147:Genes, Tumor Suppressor; D006801:Humans; D009154:Mutation; D009857:Oncogenes; D011379:Prognosis; D012307:Risk Factors