[Hepatobiliary radionuclide imaging. Clinical applications].
Iminodiacetic analogs (IDA) undergo the same metabolism as bilirubin and organic anions. After hepatocyte uptake, IDA analogs are excreted in the biliary tree and eliminated in the intestine. Technetium-99m-labeled IDA analogs provide liver and biliary tract images showing a progression from uptake to elimination. Several clinical applications are now available for the investigation of liver or biliary diseases. Hepatobiliary scintigraphy is particularly sensitive and highly specific to identify biliary atresia, acute cholécystitis and bile leak. It can also be also performed as a liver function test. It is the only technique providing real-time assessment of bile progression from the liver to the intestine.
Zerbib
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Service de Médecine Nucléaire, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson.
D000596:Amino Acids; D001656:Biliary Atresia / Q000000981:diagnostic imaging*; D002764:Cholecystitis / Q000000981:diagnostic imaging*; D006801:Humans; D007098:Imino Acids; D008099:Liver / Q000000981:diagnostic imaging*; D017093:Liver Failure / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D013667:Technetium
D000596:Amino Acids; D007098:Imino Acids; D013667:Technetium; C008109:iminodiacetic acid
Scintigraphie hépatobiliaire: Applications cliniques.