title: Non-invasive measurement of brain activity using functional MRI: toward the study of brain response to acupuncture stimulation.
abstract: We studied functional MRI in 15 male and 13 female normal volunteers on a clinical MRI system using gradient echo sequence. During the experiments, brain activation was induced by grasping the unilateral hand once or twice a second for motor tasks. A localized increase of MRI signal in the contralateral motor cortex was observed in 17 out of 21 cases (81%) under right hand motor task and 11 out of 21 cases (52%) under left hand motor task. The application of this method may be useful to evaluate brain response to acupuncture.
authors.affiliation: Department of Neurosurgery, Meiji College of Oriental Medicine, Kyoto, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yoshida
authors.forename: C
authors.initials: C
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Umeda
authors.forename: T
authors.initials: T
authors.lastname: Higuchi
authors.forename: M
authors.initials: M
authors.lastname: Fukunaga
authors.forename: S
authors.initials: S
authors.lastname: Naruse
mesh_terms: D015670:Acupuncture Therapy; D000328:Adult; D001921:Brain / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012016:Reference Values; D013997:Time Factors