Physical mapping of the human ELA1 gene between D12S361 and D12S347 on chromosome 12q13.
ELA1, the pancreatic elastase 1 gene, is conserved in mammalian genomes. ELA1 was previously mapped to chromosome 12 using a panel of mouse-human somatic cell hybrids. We now report the physical and cytogenetic localization of the ELA1 gene. On the physical map, ELA1 is adjacent to the polymorphic marker AFMa283yg1 and between D12S361 and D12S347. Using fluorescence in situ hybridization, we determined that ELA1 maps to 12q13.
Davies
R L
RL
Department of Biology, Sweet Briar College, Virginia 24595, USA.
Yoon
S J
SJ
Weissenbach
J
J
Ward
D
D
Krauter
K
K
Kucherlapati
R
R
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D002881:Chromosomes, Human, Pair 12; D017124:Conserved Sequence; D017931:DNA Primers; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D008322:Mammals; D051379:Mice; D008969:Molecular Sequence Data; D010196:Pancreatic Elastase / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
D017931:DNA Primers; D005819:Genetic Markers; D010196:Pancreatic Elastase