title: [Distribution of p27 and gp70 feline leukemia virus antigens in various tissues].
abstract: Application of immunocytochemical methods (DP, IP, PAP, APAAP and IP-IP) has confirmed the existence of p27 and gp70 feline leukosis viral antigens (FeLV) in various tissues of 22 cats. Both viral antigens were found in bone marrow stem cells, but p27 antigens were mostly found in epithelial cells of intestinal crypts. In splenic T-lymphocytes and mediastinal lymph nodes the predominance of gp70 antigens in FeLV was confirmed, while the tropism of leukosis viruses in the lung was inclined to epithelial cells of bronchial glands where p27 antigens were dominant.
authors.affiliation: Univerzitet u Beogradu, Veterinarski fakultet, Katedra za patolosku morfologiju, Beograd.
authors.forename: S
authors.initials: S
authors.lastname: Kovacević
authors.forename: M
authors.initials: M
authors.lastname: Knezević
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D002415:Cats; D005260:Female; D015683:Gene Products, gag / Q000032:analysis*; D007150:Immunohistochemistry; D005256:Leukemia Virus, Feline / Q000276:immunology*; D016582:Leukemia, Feline / Q000276:immunology*; D008297:Male; D015682:Retroviridae Proteins, Oncogenic / Q000032:analysis*; D014759:Viral Envelope Proteins / Q000032:analysis*
chemical_list: D000956:Antigens, Viral; D015683:Gene Products, gag; D015682:Retroviridae Proteins, Oncogenic; D014759:Viral Envelope Proteins; C073723:glycoprotein gp70, Feline leukemia virus
vernacular_title: Distribucija p27 i gp70 antigena virusa leukoze macaka u razlicitim tkivima.