title: Three-dimensional architecture of human cutaneous vascular lesions: a scanning electron microscopic study of corrosion casts.
abstract: Corrosion casts were made from angiosarcoma of the scalp of an elderly person, Klippel-Trenaunay syndrome, pseudo-Kaposi's sarcoma, diffuse neonatal hemangiomatosis, cavernous hemangioma and arteriovenous malformation and were examined by scanning electron microscopy (SEM). The normal scalp from a cadaver was studied as a control for the angiosarcoma of the scalp. the SEM of the vascular corrosion casts clearly demonstrated the fine three-dimensional (3-D) architectures of malignant and benign cutaneous vascular lesions; the superficial fine and medium-sized vascular networks of the skin were replaced by abnormal balloon-like dilatations, extravasated fringes, glomerular structures, sinusoidal vessels or localized bulla-like structures of the capillary loops, depending on the nature of the cutaneous vascular lesions. The corrosion cast technique is helpful for understanding the 3-D patterns of various vascular lesions.
authors.affiliation: Department of Dermatology, University of Ehime School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Arashiro
authors.forename: H
authors.initials: H
authors.lastname: Ohtsuka
authors.forename: Y
authors.initials: Y
authors.lastname: Miki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001165:Arteriovenous Malformations / Q000473:pathology; D001808:Blood Vessels / Q000648:ultrastructure; D002648:Child; D016319:Corrosion Casting; D005260:Female; D018324:Hemangioma, Capillary / Q000098:blood supply; D006392:Hemangioma, Cavernous / Q000098:blood supply; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000473:pathology; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000098:blood supply; D012867:Skin / Q000098:blood supply*; D017445:Skin Diseases, Vascular / Q000473:pathology*; D012878:Skin Neoplasms / Q000098:blood supply*