title: Orally active squalene synthase inhibitors: bis((acyloxy)alkyl) prodrugs of the alpha-phosphonosulfonic acid moiety.
authors.affiliation: Bristol-Myers Sqibb Pharmaceutical Research Institute, Princeton, New Jersey 08543, USA.
authors.forename: J K
authors.initials: JK
authors.lastname: Dickson
authors.forename: S A
authors.initials: SA
authors.lastname: Biller
authors.forename: D R
authors.initials: DR
authors.lastname: Magnin
authors.forename: E W
authors.initials: EW
authors.lastname: Petrillo
authors.forename: J W
authors.initials: JW
authors.lastname: Hillyer
authors.forename: D C
authors.initials: DC
authors.lastname: Hsieh
authors.forename: S J
authors.initials: SJ
authors.lastname: Lan
authors.forename: J K
authors.initials: JK
authors.lastname: Rinehart
authors.forename: R E
authors.initials: RE
authors.lastname: Gregg
authors.forename: T W
authors.initials: TW
authors.lastname: Harrity
authors.forename: K G
authors.initials: KG
authors.lastname: Jolibois
authors.forename: S S
authors.initials: SS
authors.lastname: Kalinowski
authors.forename: L K
authors.initials: LK
authors.lastname: Kunselman
authors.forename: K A
authors.initials: KA
authors.lastname: Mookhtiar
authors.forename: C P
authors.initials: CP
authors.lastname: Ciosek
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors*; D006168:Guinea Pigs; D000960:Hypolipidemic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D011355:Prodrugs / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D013451:Sulfonic Acids / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D000960:Hypolipidemic Agents; D011355:Prodrugs; D013451:Sulfonic Acids; D013186:Farnesyl-Diphosphate Farnesyltransferase