title: [Transrectal ultrasound guided biopsies in 266 patients].
abstract: BACKGROUND
  The objective of this study is to evaluate the diagnostic utility of digital rectal examination (DRE), prostate specific antigen (PSA) and transrectal ultrasonography (TRUS) for prostate cancer.
  
  
  METHODS
  On 266 patients ultrasonography guided transrectal biopsies were performed using the automatic biopsy gun fitted with an 18 gauge biopsy needle.
  
  
  RESULTS
  There was no major complication. Cancers were found in 52 patients (19.5%), and 16 of them were not identified by echography. Among 67 hypoechoic areas detected by echography, 36 (53.7%) were found to be cancer. The positive predictive value of DRE was 52.1% and that of PSA and TRUS were 24.4% and 53.7%, especially the rate increased to 93.7% by combining of these three techniques.
  
  
  CONCLUSIONS
  These results suggest that the use of DRE, PSA in conjunction with TRUS enhances early detection of prostate cancer.
authors.affiliation: Department of Urology, Hamamatsu University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Kurita
authors.forename: S
authors.initials: S
authors.lastname: Kageyama
authors.forename: T
authors.initials: T
authors.lastname: Ushiyama
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Fujita
authors.forename: K
authors.initials: K
authors.lastname: Kawabe
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010173:Palpation; D011237:Predictive Value of Tests; D017430:Prostate-Specific Antigen / Q000032:analysis; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012007:Rectum; D014463:Ultrasonography
chemical_list: D017430:Prostate-Specific Antigen