title: Globule leukocytes in transitional cell hyperplasia and carcinomas of aged mice.
abstract: Globule leukocytes (GLs) infiltrating in transitional cell hyperplasia and carcinomas of aged BDF1 mice were pathologically examined. The intracytoplasmic granules of globule leukocytes showed a variety of reactivity to histochemical staining for polysaccharides and were ultrastructurally composed of homogeneous electron dense material, occasionally containing crystaloids or vesicles. The GL infiltrating in tumor tissue is extremely rare.
authors.affiliation: Safety Research Laboratory, Tanabe Seiyaku Co., Ltd., Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Kawai
mesh_terms: D000375:Aging; D000818:Animals; D002295:Carcinoma, Transitional Cell / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006651:Histocytochemistry; D006965:Hyperplasia; D007962:Leukocytes / Q000473:pathology*; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D009369:Neoplasms / Q000473:pathology / Q000662:veterinary*; D012376:Rodent Diseases / Q000473:pathology*; D014516:Ureteral Neoplasms / Q000473:pathology / Q000662:veterinary