title: Torsional properties of healed canine diaphyseal defects grafted with a fibrillar collagen and hydroxyapatite/tricalcium phosphate composite.
abstract: The need for alternatives to autogenous bone grafts is widely recognized. This study compared the torsional strength of canine femora 1 year after grafting with one of three forms of a collagen/hydroxyapatite/tricalcium phosphate bone grafting material (COLLAGRAFTTM), autogenous bone, or no graft. The groups were compared to each other and to the unoperated contralateral femora. Results of torsional testing were evaluated for torsional strength, torsional displacement, total energy to fracture and White fracture mode. Data analysis showed lower torsional strength of the operated vs. unoperated femora with the exception of morsellized COLLAGRAFTTM material, which had higher strength. However, the only difference in the operated groups was that the morsellized COLLAGRAFTTM had greater strength than several groups including the autogenous bone group. There was no difference found in angular displacement between any of the groups. However, there was a difference in the energy to fracture in both strip forms of the COLLAGRAFTTM. The final conclusion is that in this model, grafting with COLLAGRAFTTM provided torsional properties at one year postoperatively at least equivalent to autogenous bone.
authors.affiliation: Department of Orthopaedic Surgery, University of Mississippi Medical Center, Jackson 39216, USA.
authors.forename: L D
authors.initials: LD
authors.lastname: Zardiackas
authors.forename: R D
authors.initials: RD
authors.lastname: Teasdall
authors.forename: R J
authors.initials: RJ
authors.lastname: Black
authors.forename: G S
authors.initials: GS
authors.lastname: Jones
authors.forename: K R
authors.initials: KR
authors.lastname: St John
authors.forename: L D
authors.initials: LD
authors.lastname: Dillon
authors.forename: J L
authors.initials: JL
authors.lastname: Hughes
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D016025:Bone Transplantation; D002130:Calcium Phosphates; D003094:Collagen; D018483:Diaphyses / Q000601:surgery*; D004285:Dogs; D005264:Femoral Fractures / Q000000981:diagnostic imaging / Q000601:surgery*; D005269:Femur / Q000000981:diagnostic imaging; D019736:Prostheses and Implants; D011859:Radiography; D013314:Stress, Mechanical; D013997:Time Factors; D014182:Transplantation, Autologous
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; C065819:Collagraft; D003094:Collagen