Pulmonary fibrosis and sea-blue histiocyte infiltration in a patient with primary myelofibrosis.
The authors present the case of a 73 year old man with primary myelofibrosis, pulmonary fibrosis, and acquired sea-blue histiocytosis, who died of respiratory failure. Pathology of the lungs revealed infiltration by sea-blue histiocytes, and fibrosis in the alveolar septa, and clumps of these cells filling the alveolar spaces. Megakaryocytes were also occasionally observed in the alveolar capillaries.
Yamauchi
K
K
Dept of Internal Medicine, School of Medicine, Tokai University, Japan.
Shimamura
K
K
D000368:Aged; D001706:Biopsy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D055728:Primary Myelofibrosis / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D011658:Pulmonary Fibrosis / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D012618:Sea-Blue Histiocyte Syndrome / Q000150:complications / Q000473:pathology* / Q000503:physiopathology