title: A rational reconstruction of INTERNIST-I using PROTEGE-II.
abstract: PROTEGE-II is a methodology and a suite of tools that allow developers to build and maintain knowledge-based systems in a principled manner. We used PROTEGE-II to reconstruct the well-known INTERNIST-I system, demonstrating the role of a domain ontology (a framework for specification of a model of an application area), a reusable problem-solving method, and declarative mapping relations in creating a new, working program. PROTEGE-II generates automatically a domain-specific knowledge-acquisition tool, which, in the case of the INTERNIST-I reconstruction, has much of the functionality of the QMR-KAT knowledge-acquisition tool. This study provides a means to understand better both the PROTEGE-II methodology and the models that underlie INTERNIST-I.
authors.affiliation: Section on Medical Informatics, Stanford University School of Medicine, CA 94305-5479, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Musen
authors.forename: J H
authors.initials: JH
authors.lastname: Gennari
authors.forename: W W
authors.initials: WW
authors.lastname: Wong
mesh_terms: D001185:Artificial Intelligence; D003199:Computer Systems; D007388:Internal Medicine; D012984:Software