title: Changes in bone mineral density of the proximal tibia after uncemented total knee arthroplasty. A 3-year follow-up of 25 knees.
abstract: We measured bone remodeling of the proximal tibia prospectively for 3 years after uncemented total knee arthroplasty (TKA) in 25 knees with primary arthrosis. In the trabecular bone below the tibial component, bone mineral density (BMD) was measured in 6 different regions of interest (ROI), using dual photon absorptiometry (DPA). In the tibial condyles, where the change in knee alignment indicated that the load was reduced postoperatively, a fast bone loss of 7-20% was seen during the first 6 months after surgery. A small, but significant increase in BMD of 2-7% was seen in the tibial condyles, where the load was increased. On average, the density for all ROI below the tibial component showed a significant and progressive decrease in BMD, reaching 22% at 3 years follow-up.
authors.affiliation: Department of Orthopedics U 2161, Rigshospitalet, University of Copenhagen, Denmark.
authors.forename: M M
authors.initials: MM
authors.lastname: Petersen
authors.forename: P T
authors.initials: PT
authors.lastname: Nielsen
authors.forename: J B
authors.initials: JB
authors.lastname: Lauritzen
authors.forename: B
authors.initials: B
authors.lastname: Lund
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D016723:Bone Remodeling; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013977:Tibia / Q000503:physiopathology*