title: Synthesis and properties of cross-linked DNA duplexes.
abstract: A method has been devised to synthesize DNA duplexes with covalently connected strands. The structure of cross-linked duplexes was confirmed by a reaction with the restriction endonuclease AluI. The thermal stability of the resulting compounds was investigated.
authors.affiliation: Chemistry Department, Moscow State University, Russian Federation.
authors.forename: S I
authors.initials: SI
authors.lastname: Antsypovich
authors.forename: T S
authors.initials: TS
authors.lastname: Oretskaya
authors.forename: E A
authors.initials: EA
authors.lastname: Romanova
authors.forename: E M
authors.initials: EM
authors.lastname: Volkov
authors.forename: V N
authors.initials: VN
authors.lastname: Tashlitsky
authors.forename: M
authors.initials: M
authors.lastname: Vasser
authors.forename: Z A
authors.initials: ZA
authors.lastname: Shabarova
mesh_terms: D001483:Base Sequence; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003432:Cross-Linking Reagents / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D015252:Deoxyribonucleases, Type II Site-Specific / Q000737:chemistry / Q000378:metabolism; D004586:Electrophoresis / Q000379:methods; D006358:Hot Temperature; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016328:NF-kappa B / Q000737:chemistry / Q000378:metabolism; D009841:Oligonucleotides / Q000138:chemical synthesis; D013057:Spectrum Analysis; D013696:Temperature; D014466:Ultraviolet Rays; D014529:Uridine / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D003432:Cross-Linking Reagents; D016328:NF-kappa B; D009841:Oligonucleotides; D004247:DNA; C024669:endodeoxyribonuclease AluI; D015252:Deoxyribonucleases, Type II Site-Specific; D014529:Uridine