[The clinical manifestations of HIV infection during seroconversion].
21 seroconversion HIV-infected subjects have been examined. 16 of them presented with acute symptoms. The disease in the period of seroconversion manifested with fever, weakness, headache, pain in the throat, enlargement of peripheral lymph nodes, polymorphous eruption. Typical mononucleosis-like syndrome occurred in 3 patients only. Half of the patients had subclinical disease, no eruption was seen. Because of clinical indications only 8 of 21 patients were examined for HIV infection. One-third of the patients in seroconversion had moderate thrombocytopenia, probably of autoimmune nature. Autoimmune disorder of the thyroid was registered in 1 patient. The diagnosis of acute HIV infection is not easy in view of rare occurrence of immunodeficiency typical for this infection. Candidiasis of the mucosa was seen in 37.5%, low levels of CD4-lymphocytes in 66.7% of the cases.
Kravchenko
A V
AV
Iurin
O G
OG
Buravtsova
E V
EV
Pankova
G Iu
GIu
Serebrovskaia
L V
LV
Galina
M V
MV
Roslyĭ
I M
IM
Pokrovskiĭ
V V
VV
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002180:Candidiasis, Oral / Q000175:diagnosis; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000175:diagnosis*; D006679:HIV Seropositivity / Q000175:diagnosis*; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged
D015483:HIV Antibodies
Klinicheskie proiavleniia VICh-infektsii v periode serokonversii.