Organ function during early acute renal failure does not predict survival in long-term intensive care.
OBJECTIVE
To examine outcome in relation to organ function variables during early acute renal failure (ARF).


METHODS
Retrospective inception cohort.


METHODS
General intensive care unit (ICU).


METHODS
69 consecutive ARF cases verified to have a creatinine clearance below 50 ml/min with no history of previous renal disease.


METHODS
ICU survival.


RESULTS
Septic severity score (SSS), creatinine clearance, thrombocyte count, bilirubin concentration, cardiac inotropic support, PaO2/FIO2 ratio and oliguria were measured. No differences related to outcome were observed in patients surviving more than 7 days after ARF diagnosis. Patients dying within 7 days of ARF had a significantly higher (worse) SSS. Organ dysfunction was established at the time of ICU admission in the majority of cases.


CONCLUSIONS
The organ function variables tested in this study are of limited predictive value during the early stage of ARF.
Størset
P
P
Department of Anaesthesia, Ullevål University Hospital, Oslo, Norway.
Smith-Erichsen
N
N
Vaagenes
P
P
D058186:Acute Kidney Injury / Q000150:complications* / Q000175:diagnosis* / Q000401:mortality; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003422:Critical Care; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology*; D017063:Outcome Assessment, Health Care; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D018805:Sepsis / Q000209:etiology*; D012720:Severity of Illness Index; D015996:Survival Rate; D013997:Time Factors