title: FDG PET imaging of paragangliomas of the neck: comparison with MIBG SPET.
abstract: Two patients with cervical paragangliomas underwent positron emission tomography (PET) with 2-[18F]-fluoro-2-deoxy-D-glucose (FDG). There was marked tumor uptake and retention of FDG. Adjacent salivary gland accumulation of FDG was minimal, though quite prominent with meta-iodobenzylguanidine. FDG PET offers another potentially useful approach to functional imaging of these uncommon tumors, independent of the presence of specific amine uptake mechanisms or cell surface receptors required by other scintigraphic techniques.
authors.affiliation: Division of Nuclear Medicine, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Macfarlane
authors.forename: B L
authors.initials: BL
authors.lastname: Shulkin
authors.forename: K
authors.initials: K
authors.lastname: Murphy
authors.forename: G T
authors.initials: GT
authors.lastname: Wolf
mesh_terms: D019797:3-Iodobenzylguanidine; D000328:Adult; D002345:Carotid Body Tumor / Q000000981:diagnostic imaging*; D003287:Contrast Media; D003847:Deoxyglucose / Q000031:analogs & derivatives*; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D005925:Glomus Jugulare Tumor / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008875:Middle Aged; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D003287:Contrast Media; D005462:Fluorine Radioisotopes; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019788:Fluorodeoxyglucose F18; D019797:3-Iodobenzylguanidine; D003847:Deoxyglucose