BCG vaccination against tuberculosis: past disappointments and future hopes.
Three billion doses of the bacille Calmette-Guérin (BCG) vaccine have been given over the past 60 years. BCG has a widely variable ability to protect humans against tuberculosis. This article examines some of the reasons for this variability, and discusses ways in which BCG vaccination might be improved.
Roche
P W
PW
Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia.
Triccas
J A
JA
Winter
N
N
D000818:Animals; D001500:BCG Vaccine / Q000008:administration & dosage*; D005544:Forecasting; D006801:Humans; D014376:Tuberculosis / Q000517:prevention & control*
D001500:BCG Vaccine