title: Evaluation of endoscopic sinus surgery for chronic sinusitis: post-operative erythromycin therapy.
abstract: We discuss the results of endoscopic endonasal sinus surgery for chronic pan-sinusitis characterized by nasal polyposis, especially the effects of post-operative long-term administration of low-dose erythromycin (EM) therapy. The subjects analysed in this retrospective study are surgical cases who had initially been operated for chronic pan-sinusitis. They are classified into one group who has received a post-operative long-term, low-dose EM regimen and into another group who has not received this treatment. The groups have been compared with respect to: (1) the degree of improvement in the post-operative subjective symptoms; (2) postoperative objective findings of the ethmoidal sinus and the ostium of the frontal sinus; and (3) the degree of improvement in the maxillary sinus lesion. Better improvement is achieved in subjective symptoms and objective findings in the EM group than in the non-EM group.
authors.affiliation: Department of Otolaryngology, Jikei University School of Medicine, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Moriyama
authors.forename: K
authors.initials: K
authors.lastname: Yanagi
authors.forename: N
authors.initials: N
authors.lastname: Ohtori
authors.forename: M
authors.initials: M
authors.lastname: Fukami
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004724:Endoscopy; D004917:Erythromycin / Q000008:administration & dosage / Q000627:therapeutic use*; D015521:Ethmoid Sinusitis / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D015523:Maxillary Sinusitis / Q000188:drug therapy / Q000601:surgery; D008875:Middle Aged; D011182:Postoperative Care; D012189:Retrospective Studies; D012852:Sinusitis / Q000188:drug therapy* / Q000601:surgery*
chemical_list: D004917:Erythromycin