title: Prediction of complications following unintentional caustic ingestion in children. Is endoscopy always necessary?
abstract: The records of 115 children hospitalized following caustic ingestion over an 18.5-year period from 1976 to 1994 were reviewed. The relationship between types of product ingested, signs and symptoms, degree of esophageal injury and complications was analyzed. All complications were the result of strong alkali ingestion (sensitivity = 1.0). Among the 102 incident patients, 36.8% of lye ingestions resulted in complications, whereas only 2.7% (one) of automatic dishwasher detergent (ADD) ingestions caused any complications (p < 0.01). Endoscopy 6 h to 4 days after injury was accurate in predicting or identifying complications in all types of strong alkali ingestions. In lye ingestions, endoscopy was not superior to the test, "one or more signs or symptoms" in predicting complications (predictivity = 1.0). Endoscopy is recommended to establish or confirm a prognosis, or to identify acute respiratory complications, in symptomatic ingestions of lye or ammonia water, in children with respiratory symptoms, and in rare cases of severe symptoms following ADD or strong acid ingestion. It is suggested that children who are non-symptomatic following unintentional ingestions are not at risk of complications and do not need endoscopic examination.
authors.affiliation: Department of Pediatrics, Aarhus University Hospital, Denmark.
authors.forename: H B
authors.initials: HB
authors.lastname: Christesen
mesh_terms: D000293:Adolescent; D000402:Airway Obstruction / Q000175:diagnosis / Q000209:etiology; D002057:Burns, Chemical / Q000175:diagnosis*; D002424:Caustics / Q000506:poisoning*; D002648:Child; D016001:Confidence Intervals; D004487:Edema / Q000139:chemically induced / Q000175:diagnosis; D004825:Epiglottis; D004935:Esophageal Diseases / Q000139:chemically induced / Q000175:diagnosis; D004940:Esophageal Stenosis / Q000139:chemically induced / Q000175:diagnosis; D004945:Esophagoscopy; D004947:Esophagus / Q000293:injuries*; D006795:Household Products / Q000506:poisoning*; D006801:Humans; D016017:Odds Ratio; D009960:Oropharynx / Q000293:injuries; D011237:Predictive Value of Tests
chemical_list: D002424:Caustics