title: [The treatment of chronic atrial fibrillation].
abstract: Atrial fibrillation is a common arrhythmia. It is associated with increased morbidity and mortality, in part secondary to an increased rate of thromboembolism. Considering the arrhythmia's duration, a chronic and paroxysmal type can be recognized. Only the former will be discussed here. Treatment of atrial fibrillation should be aimed at restoring sinus rhythm. This may improve exercise tolerance and alleviate symptoms. In addition, it may obviate the need for antithrombotic therapy. Electrical cardioversion is the method of choice to restore sinus rhythm in patients with chronic atrial fibrillation. To prevent arrhythmia relapses, anti-arrhythmic drugs are often prescribed. These drugs, however, may have serious side effects, e.g. proarrhythmia. The pros and cons of antiarrhythmics should therefore be considered seriously before prescribing these drugs. An alternative strategy is to optimize ventricular rate response (usually pharmacologically) while the patient maintains in atrial fibrillation. To prevent thromboembolism, however, the use of antithrombotic is strongly recommended in most of these patients.
authors.affiliation: Afdeling Cardiologie, Acadamisch Ziekenhuis Groningen.
authors.forename: A T
authors.initials: AT
authors.lastname: Gosselink
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000009:adverse effects / Q000145:classification / Q000627:therapeutic use*; D000925:Anticoagulants / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D002908:Chronic Disease; D004554:Electric Countershock; D006801:Humans; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control; D016276:Ventricular Function / Q000187:drug effects
chemical_list: D000889:Anti-Arrhythmia Agents; D000925:Anticoagulants
vernacular_title: De behandeling van chronisch boezemfibrilleren.