title: [Cytogenetic abnormalities in seven patients with the Sezary syndrome].
abstract: The cytogenetic studies performed on 7 patients diagnosed of Sezary's syndrome are reported. The chromosomal study was made after 72 hours of culture of phytohaemagglutinin-stimulated peripheral blood. The 7 patients had abnormal karyotypes, the numeral alterations involving chromosomes 10 and 13, whereas the structural abnormalities affected chromosomes 1, 2, 4, 6 and 14. The large-cell variant has been associated with tetraploidy and the small-cell variant with diploidy, but this fact was not confirmed in the present series.
authors.affiliation: Laboratori de Citologia Hematològica, Hospital Central l'Aliança, Barcelona.
authors.forename: F
authors.initials: F
authors.lastname: Solé
authors.forename: S
authors.initials: S
authors.lastname: Woessner
authors.forename: T
authors.initials: T
authors.lastname: Vallespí
authors.forename: A
authors.initials: A
authors.lastname: Domingo
authors.forename: A
authors.initials: A
authors.lastname: Pérez Losada
authors.forename: L
authors.initials: L
authors.lastname: Florensa
authors.forename: D
authors.initials: D
authors.lastname: Irriguible
authors.forename: B
authors.initials: B
authors.lastname: Espinet
authors.forename: J
authors.initials: J
authors.lastname: Sans-Sabrafén
mesh_terms: D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D012751:Sezary Syndrome / Q000235:genetics*
vernacular_title: Alteraciones citogenéticas en siete pacientes con síndrome de Sézary.