[Clinical significance of fungi-bearing status of hospitalized patients].
The samples for fungi culture were collected from 11 body parts of 1109 patients who had been admitted to hospitals in Wuhan for more than 3 days. The body parts included the cavities and foramina (inner canthus, nasal vestibule, external auditory canal), skin (finger raphe, cubital fossa, axillary fossa, nipple), and mucosa (pharynx, vagina, coronary sulcus and anal canal). 201 healthy subjects were also examined and served as controls. It was found that the total fungus-bearing rate in hospitalized patients was 88.73% (984/1109), while the rate in healthy subject was 76.62% (154/201) (X2 = 21.61). Among the hospitalized patients, the fungus-bearing rate in patients with leukemia, tumors, connective tissue diseases or severe infectious diseases was significantly higher than other patients (X2 = 4.30-9.87). In the hospitalized patients, the body parts with highest fungus-bearing rates were cavities and foramina, 80.70% (895/1109) for patients and 71.64% (144/201) for healthy subjects respectively. The skin had lowest fungus-bearing rate. 20.02% (222/1109) and 13.43% (26/201), and the mucosa had a rate of 50.77% (563/1109) for patients and 32.34% (65/201) respectively. The fungi in the hospitalized patients included 1884 strains (mean = 1.92 strains per case) in which the Candida accounted for 29.78% (561/1884) and Aspergilla 24.31% (458/1884) and those identified in healthy subjects covered 234 strains (mean = 1.52 strains per person) in which Penicillia accounted for 45.30% (106/234) and Saccharomycetes 26.07% (61/234). The patients who had been hospitalized for 3-10 days and over 20 days had higher fungus-bearing rate as compared with those who had been hospitalized for 10 to 20 days (X2 = 5.633-97.09). The patients before the administration of antibiotics and adrenocortical steroid and those who had been given these medicines for over 20 days had a higher fungus-bearing rate than those who had been on these medicines for 1-20 days.
Zheng
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Department of Dermatology and venereal Diseases, Xiehe Hospital, Tongji Medical University, Wuhan.
Wu
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Y
Tang
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Z
D000293:Adolescent; D000328:Adult; D001228:Aspergillosis / Q000453:epidemiology; D002177:Candidiasis / Q000453:epidemiology; D002353:Carrier State / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007223:Infant; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000453:epidemiology*