title: Predicting the donor liver lobe weight from body weight for split-liver transplantation.
abstract: It is possible to obtain two good-quality hepatic transplants from a single cadaveric liver by separation of the right and left lobes of the liver. We attempted to define a relationship based only on donor body weight for predicting donor total liver weight as well as donor right (segments V-VIII) and left (segments II-IV) hepatic lobe weight. Segment I (caudate lobe) is resected and thus lost in this procedure. The study was performed on 60 human cadaveric livers. We correlated cadaveric body weight (mean +/- SD), 72.43 +/- 9.54 kg, with total liver weight, 1.54 +/- 0.36 kg, and right and left lobe weight, 0.88 +/- 0.23 kg and 0.65 +/- 0.17 kg, respectively, with total liver weight. A formula was obtained by linear regression which provided the following relationships: total liver weight (g) = [245.57 + 17.92 x (body weight, kg)]; right lobe weight (g) = [67.58 + 0.52 x (total liver weight, g)]; left lobe weight (g) = [-63.38 + 0.47 x (total liver weight, g)]. The selection of the recipient on the liver transplant waiting list can be made on the basis of these relationships.
authors.affiliation: Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de São Paulo, Brasil.
authors.forename: E
authors.initials: E
authors.lastname: Chaib
authors.forename: M M
authors.initials: MM
authors.lastname: Morales
authors.forename: M B
authors.initials: MB
authors.lastname: Bordalo
authors.forename: L G
authors.initials: LG
authors.lastname: Antonio
authors.forename: L F
authors.initials: LF
authors.lastname: Feijo
authors.forename: R Y
authors.initials: RY
authors.lastname: Ishida
authors.forename: J
authors.initials: J
authors.lastname: Lima Júnior
authors.forename: P A
authors.initials: PA
authors.lastname: Nunes
mesh_terms: D000328:Adult; D000368:Aged; D001835:Body Weight; D006801:Humans; D008099:Liver / Q000033:anatomy & histology*; D016031:Liver Transplantation / Q000379:methods*; D008875:Middle Aged; D009929:Organ Size; D018579:Patient Selection; D011237:Predictive Value of Tests; D012044:Regression Analysis; D014019:Tissue Donors