Post-transplant lymphoma in a liver allograft.
We describe the development of a lymphoma in a liver allograft shortly after orthotopic liver transplantation. Aspiration and core biopsies of the nodule were persistently negative so that a diagnosis could not be made until the patient underwent retransplantation, when examination of the liver resection specimen revealed a B-cell lymphoma. Using a rapid technique based on the polymerase chain reaction, we were able to demonstrate that the tumor was of donor origin.
Ribas
Y
Y
Liver Transplant Unit, C.S.U. Bellvitge, Hospitalet de Llobregat, Barcelona, Spain.
Rafecas
A
A
Figueras
J
J
Benasco
C
C
Fabregat
J
J
Torras
J
J
Cañas
C
C
Valls
C
C
Volpini
V
V
Banchs
I
I
D001483:Base Sequence; D004273:DNA, Neoplasm / Q000032:analysis*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000209:etiology*; D016031:Liver Transplantation / Q000009:adverse effects*; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D014184:Transplantation, Homologous
D004273:DNA, Neoplasm