Obstructive sleep hypopnea syndrome in a patient with Marfan syndrome treated with oxygen therapy.
A patient with Marfan's syndrome and obstructive sleep hypopnea syndrome is reported. She had complained about insomnia, tiredness and hypersomnolence lasting 2 years. A complete nightly polysomnography revealed 94 obstructive hypopneas (the hypopnea index was 12.85) and no obstructive apneas. Presumably an increased laxity of the pharyngeal wall was responsible for the phenomenon. A therapy with CPAP was started, but was not tolerated by the patient. Oxygen therapy on the other hand turned out to be effective and well tolerated.
Verbraecken
J A
JA
Department of Respiratory Medicine, University Hospital of Antwerp, Belgium.
Willemen
M
M
De Cock
W
W
Coen
E
E
Van de Heyning
P
P
De Backer
W
W
D000328:Adult; D005260:Female; D006801:Humans; D008382:Marfan Syndrome / Q000150:complications*; D010102:Oxygen Inhalation Therapy / Q000295:instrumentation; D017286:Polysomnography; D011175:Positive-Pressure Respiration; D012891:Sleep Apnea Syndromes / Q000209:etiology* / Q000628:therapy*