Heat-shock proteins in host-pathogen interactions: implications for cystic fibrosis.
The expression of heat-shock proteins by both pathogen and host cells during the phagocytosis of Staphylococcus aureus and Pseudomonas aeruginosa, two bacterial species that colonize the airways of patients with cystic fibrosis, probably contributes to pulmonary inflammation in cystic fibrosis. Here, we discuss the likely signals for heat-shock-protein induction within host and bacterial cells.
Polla
B S
BS
University Paris V, Laboratory of Respiratory Physiology, UFR Cochin Port-Royal, France.
Mariéthoz
E
E
Hubert
D
D
Barazzone
C
C
D001426:Bacterial Proteins / Q000276:immunology / Q000502:physiology*; D002462:Cell Membrane / Q000378:metabolism; D003550:Cystic Fibrosis / Q000276:immunology / Q000382:microbiology*; D006360:Heat-Shock Proteins / Q000276:immunology / Q000502:physiology*; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000276:immunology; D013211:Staphylococcus aureus / Q000276:immunology
D001426:Bacterial Proteins; D006360:Heat-Shock Proteins