title: AH17, a new non-polyenic antifungal antibiotic produced by a strain of Spirillospora.
abstract: An antibiotic (AH17) was produced by Spirillospora strain 719. This substance was obtained only from the broth filtrate after precipitation with acetic acid followed by extraction with n-butanol. Its purification was carried out by thin layer chromatography on silica gel followed by HPLC procedures. It showed activity against Gram-positive and Gram-negative bacteria and fungi. The spectroscopic and chemical properties were examined and indicated that AH17 was a quinone. It seems that this is a new antibiotic from Spirillospora.
authors.affiliation: Laboratoire de Microbiologie, Université des Sciences et de la Technologie Houari-Boumediène, Alger-Gare, Algeria.
authors.forename: H
authors.initials: H
authors.lastname: Hacène
authors.forename: G
authors.initials: G
authors.lastname: Lefebvre
mesh_terms: D000192:Actinomycetales / Q000378:metabolism*; D000935:Antifungal Agents / Q000096:biosynthesis / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development; D005658:Fungi / Q000187:drug effects / Q000254:growth & development
chemical_list: D000935:Antifungal Agents