Diffuse bone marrow uptake [123I]MIBG in neuroblastoma: an "MIBG super scan" case report.
We present the case of a 3-year-old child with neuroblastoma metastatic to the bone marrow. [123I]MIBG total body scintigraphy revealed a diffuse pattern of intense fixation throughout the skeleton. This was analogous to the "super scan" described with 99mTc-MDP bone scintigraphy when extensive metastatic or metabolic bone disease is present. Essentially, a high bone-to-soft tissue ratio was found without uptake in the liver, kidney and bladder, owing to a "steal" mechanism caused by the avid bone metastases.
Giammarile
F
F
Service de Médecine Nucléaire, Institut Gustave Roussy, Villejuif, France.
Olier
A L
AL
Lumbroso
J
J
D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000473:pathology; D001853:Bone Marrow / Q000000981:diagnostic imaging; D019046:Bone Marrow Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002675:Child, Preschool; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D009447:Neuroblastoma / Q000000981:diagnostic imaging* / Q000556:secondary*; D011877:Radionuclide Imaging
D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine