CD34-positive blastoma in a patient with idiopathic myelofibrosis.
We report CD34-positive "blastoma" which developed in a patient with idiopathic myelofibrosis (IMF). A 48-year-old woman was diagnosed as having essential thrombocythemia, then the disease had transformed into IMF 41 months later. Finally, a subcutaneous tumor, composed of blastic cells positive for CD34 but negative for lineage-specific antigens, developed without any evidence of systemic leukemia transformation.
Komeno
T
T
Division of Hematology, University of Tsukuba.
Ninomiya
H
H
Itoh
T
T
Hasegawa
Y
Y
Kobayashi
T
T
Mori
N
N
Nagasawa
T
T
Abe
T
T
D018952:Antigens, CD34 / Q000032:analysis*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000150:complications*; D013922:Thrombocytosis / Q000150:complications
D018952:Antigens, CD34