[Parkinsonism induced by sodium valproate].
Parkinsonism is a rare side effect of treatment with sodium valproate. We report 2 elderly women who developed parkinsonian syndrome several years after starting valproate therapy, and in whom symptoms disappeared when treatment was withdrawn. These cases, along with others in the literature, may support experimental evidence for the importance of GABAergic modulation in motor control.
del Real Francia
M A
MA
Servicio de Neurología, Complejo Hospitalario de Ciudad Real.
Sanz Martínez
J
J
Vaamonde Gamo
J
J
Gudín Rodríguez-Magariños
M
M
Ibáñez Alonso
R
R
Riñón
V
V
D000368:Aged; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy; D005260:Female; D006801:Humans; D010300:Parkinson Disease / Q000209:etiology*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D000927:Anticonvulsants; D014635:Valproic Acid
Síndrome parkinsoniano inducido por valproato sódico.