title: Development of an intra blood circuit membrane oxygenator.
abstract: This paper deals with development of a prototype intra blood circuit membrane oxygenator. The shell of the oxygenator is made of a flexible polyvinyl chloride tube. The membrane surface area of the oxygenator is 0.3 m2. The total blood priming volume, including the oxygenator, was only 400-600 ml, which allows for extracorporeal circulation with no additional blood. Its potential was evaluated in in vitro experiments. The oxygen transfer rate was 140 ml/min, and the carbon dioxide transfer rate was 85 ml/min at a blood flow rate of 3 l/min. The device could make blood circuits simpler and more compact, with lower priming volumes. This indicates that it may prove useful for extracorporeal circulation.
authors.affiliation: Department of Applied Electronic Engineering, Tokyo Denki University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fukui
authors.forename: A
authors.initials: A
authors.lastname: Funakubo
authors.forename: T
authors.initials: T
authors.lastname: Kawamura
mesh_terms: D001698:Biomedical Engineering; D001783:Blood Flow Velocity; D002245:Carbon Dioxide / Q000097:blood; D005069:Evaluation Studies as Topic; D005112:Extracorporeal Circulation; D015199:Extracorporeal Membrane Oxygenation; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D010100:Oxygen / Q000097:blood; D010107:Oxygenators, Membrane / Q000009:adverse effects
chemical_list: D006454:Hemoglobins; D002245:Carbon Dioxide; D010100:Oxygen