title: Infiltrating ductal carcinoma of the breast: extensive intraductal component has no impact on lymph node involvement and survival.
abstract: The extensive intraductal component (EIC) in infiltrating ductal carcinoma (IDC) was reported to be a predictor of local recurrence. We investigated the influence of this histopathological parameter on nodal status and overall survival. In 115 patients suffering from an IDC with tumor stage FIGO I and II, 35 were EIC positive. We did not find a correlation with the nodal status. The mean follow up was 73 (+/- 38) months. EIC showed no influence on overall survival. Based on our findings, the presence of EIC is not a criterion for therapeutic decisions in IDC.
authors.affiliation: Department of Gynecology and Obstetrics, University of Vienna and Medical School, Austria.
authors.forename: E A
authors.initials: EA
authors.lastname: Joura
authors.forename: A
authors.initials: A
authors.lastname: Lösch
authors.forename: C
authors.initials: C
authors.lastname: Kainz
authors.forename: C
authors.initials: C
authors.lastname: Sam
authors.forename: E M
authors.initials: EM
authors.lastname: Joura
authors.forename: G
authors.initials: G
authors.lastname: Gitsch
authors.forename: C
authors.initials: C
authors.lastname: Dadak
authors.forename: G
authors.initials: G
authors.lastname: Breitenecker
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D015996:Survival Rate