title: Relationship between gastroesophageal reflux and gastric emptying after distal gastrectomy.
abstract: OBJECTIVE
  Our objective was to determine whether delayed gastric emptying contributes to gastroesophageal reflux after distal gastrectomy.
  
  
  METHODS
  To study gastric emptying and gastroesophageal reflux, we used a tecnnetium-labeled mixed liquid and solid test meal in 46 distal gastrectomy patients (19 with reflux symptoms and 27 without) and in 10 controls. The relationship of reflux symptoms to gastric emptying and the correlation between gastric emptying and the scintigraphic reflux index were evaluated.
  
  
  RESULTS
  The reflux index was significantly higher in the symptomatic group (9.76 +/- 5.64%) than in the asymptomatic group (4.45 +/- 2.70%). The gastric emptying half time was significantly longer in the symptomatic group (53.13 +/- 19.39 min) than in asymptomatic group (34.26 +/- 20.40 min) and in normal controls (27.31 +/- 4.60 min). There was a significant linear correlation between the scintigraphic reflux index and the gastric emptying half time (r = 0.505,p < 0.001).
  
  
  CONCLUSIONS
  These findings suggest that scintigraphy is a reasonably accurate test for detecting gastroesophageal reflux and that delayed gastric emptying plays an important role in the development of reflux after distal gastrectomy.
authors.affiliation: Second Department of Surgery, Hyogo College of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: K
authors.initials: K
authors.lastname: Nakagawa
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: J
authors.initials: J
authors.lastname: Utsunomiya
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D005746:Gastric Emptying; D005764:Gastroesophageal Reflux / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D011877:Radionuclide Imaging / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D016284:Technetium Tc 99m Pentetate
chemical_list: D016284:Technetium Tc 99m Pentetate