[Neuroleptics and nicotine].
Excessive smoking is a well know phenomenon in psychiatry. Nicotine, the most important content of cigarette tobacco, interacts with several receptors of neurotransmitters in the CNS: especially the dopaminergic system appears to be relevant in this respect. Nicotine is a potent substance to counteract neuroleptic-induced parkinsonism. On the other hand nicotine is possibly a risk-factor for tardive dyskinesia. Nicotine has enormous therapeutical implications.
Erdmann
R
R
Abteilung Klinische Psychiatrie und Psychotherapie der Medizinischen Hochschule Hannover.
D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D004409:Dyskinesia, Drug-Induced / Q000503:physiopathology; D006801:Humans; D009538:Nicotine / Q000008:administration & dosage / Q000009:adverse effects*; D010302:Parkinson Disease, Secondary / Q000139:chemically induced / Q000517:prevention & control; D011954:Receptors, Dopamine / Q000187:drug effects* / Q000502:physiology; D018079:Receptors, GABA / Q000187:drug effects / Q000502:physiology; D017470:Receptors, Glutamate / Q000187:drug effects / Q000502:physiology; D012559:Schizophrenia / Q000188:drug therapy* / Q000503:physiopathology; D012565:Schizophrenic Psychology; D012907:Smoking / Q000009:adverse effects* / Q000523:psychology
D014150:Antipsychotic Agents; D011954:Receptors, Dopamine; D018079:Receptors, GABA; D017470:Receptors, Glutamate; D009538:Nicotine
Neuroleptika und Nikotin.