title: Sequence analysis of the 5.34-kb 5' flanking region of the human rhodopsin-encoding gene.
abstract: In order to define elements which may be involved in regulating human rhodopsin expression, we have isolated and sequenced a clone containing 5.34 kb of the 5'-upstream region of the human rhodopsin-encoding gene. The 5.34-kb human segment contains multiple potential transcription factor-binding sites and a subfamily of Alu repeats. The same subfamily of Alu repeats is found 5.8 kb upstream from the human red/green visual pigment-encoding gene.
authors.affiliation: Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, School of Medicine, Philadelphia 19104-6069, USA.
authors.forename: J
authors.initials: J
authors.lastname: Bennett
authors.forename: D
authors.initials: D
authors.lastname: Sun
authors.forename: K
authors.initials: K
authors.lastname: Karikó
mesh_terms: D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D006224:Cricetinae; D005796:Genes; D006801:Humans; D008969:Molecular Sequence Data; D012045:Regulatory Sequences, Nucleic Acid; D012091:Repetitive Sequences, Nucleic Acid; D012243:Rhodopsin / Q000235:genetics*; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D014157:Transcription Factors; D012243:Rhodopsin