Non-insulin-dependent diabetes mellitus complicated with idiopathic hypoparathyroidism.
We report a case of non-insulin-dependent diabetes mellitus (NIDDM) complicated with idiopathic hypoparathyroidism. A 74-year-old male was hospitalized because of diplopia. He was revealed to have NIDDM. The levels of serum Ca and intact-PTH were 6.3 mg/dl and < 5 pg/ml, respectively. Brain computed tomography revealed abnormal calcification in the cerebral basal ganglia and the cerebellum. After recovery from hypocalcemia, the endogenous insulin secretion was normalized. It is suggested that the pathogenesis of NIDDM in this patient may have been related to an insulin secretory defect as a result of hypocalcemia in addition to the hereditary risk.
Itoh
H
H
Department of Internal Medicine, Hosogi Hospital, Kochi.
Matsuda
Y
Y
Nishiyama
M
M
Kitagawa
T
T
Kobayashi
T
T
Nio
Y
Y
Hama
S
S
Hosogi
H
H
Hiroi
T
T
Hashimoto
K
K
D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications*; D006801:Humans; D006996:Hypocalcemia / Q000097:blood / Q000209:etiology*; D007011:Hypoparathyroidism / Q000097:blood / Q000150:complications*; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D008297:Male
D007328:Insulin