Why does Escherichia coli recycle its cell wall peptides?
This review discusses the phenomenon of recycling of cell wall peptides. It is a major, though non-essential, pathway of the cell and is required for induction of beta-lactamase. Consequently, the recycling pathway is viewed as a possible signalling vehicle, informing the cell of the condition of the murein sacculus, an essential structure existing outside the cell itself. As the study of this phenomenon is in its infancy, several speculations are offered for a possible regulatory function.
Park
J T
JT
Department of Molecular Biology and Microbiology, Tufts University Health Sciences Campus, Boston, Massachusetts 02111, USA.
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002240:Carbohydrate Sequence; D002473:Cell Wall / Q000737:chemistry / Q000378:metabolism; D004790:Enzyme Induction; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D006094:Gram-Positive Bacteria / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D026901:Membrane Transport Proteins; D008969:Molecular Sequence Data; D009238:N-Acetylmuramoyl-L-alanine Amidase / Q000378:metabolism; D010455:Peptides / Q000235:genetics / Q000378:metabolism*; D010457:Peptidoglycan / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D001618:beta-Lactamases / Q000096:biosynthesis
C084284:AmpG protein, Bacteria; D001426:Bacterial Proteins; D008565:Membrane Proteins; D026901:Membrane Transport Proteins; D010455:Peptides; D010457:Peptidoglycan; C062460:AmpD protein, Bacteria; D009238:N-Acetylmuramoyl-L-alanine Amidase; D001618:beta-Lactamases