title: Improving clinical outcome with centrifugal mechanical assist for postcardiotomy ventricular failure.
abstract: Between October 1986 and May 1994, 65 patients undergoing cardiac surgery required centrifugal mechanical assist devices to separate from cardiopulmonary bypass. This experience was arbitrarily divided into early (n = 33) and recent (n = 32) groups for the purpose of comparing trends in morbidity and mortality. The incidence of mechanical assist application decreased from 2.19% in the early group to 0.96% in the recent group (p < 0.0001). Ability to wean patients from centrifugal assist increased from 33% in the early group to 53% in the more recent group, and hospital survival increased from 15 to 28%. The median chest tube drainage during the first 24 h decreased from 3,245 ml to 1,535 ml, and the incidence of renal failure decreased from 39.4% and 18.8% in the more recent group. Clinically relevant improvement in patient outcome following application of centrifugal mechanical assist for postcardiotomy ventricular failure is being observed.
authors.affiliation: University of Missouri-Columbia, MA312 Health Sciences Center 65212, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Curtis
authors.forename: J T
authors.initials: JT
authors.lastname: Walls
authors.forename: R A
authors.initials: RA
authors.lastname: Schmaltz
authors.forename: T L
authors.initials: TL
authors.lastname: Demmy
authors.forename: C
authors.initials: C
authors.lastname: Wagner-Mann
authors.forename: C
authors.initials: C
authors.lastname: McKenney
authors.forename: W
authors.initials: W
authors.lastname: Nawarawong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D002498:Centrifugation; D016009:Chi-Square Distribution; D005260:Female; D006333:Heart Failure / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D006353:Heart-Assist Devices / Q000592:standards*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome