title: Characterization of the smtA gene encoding an S-adenosylmethionine-dependent methyltransferase of Escherichia coli.
abstract: The mukB operon is located at 21 min on the Escherichia coli chromosome and seems to consist of four genes, orf30 (smtA), mukF, mukE, and mukB. Based on sequence similarity, the promoter-proximal gene, orf30 (smtA), could encode an S-adenosylmethionine-dependent methyltransferase. The smtA gene is not essential for cell growth and its expression is positively regulated by H-NS, an Escherichia coli histone-like protein.
authors.affiliation: Department of Molecular Cell Biology, Kumamoto University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamanaka
authors.forename: T
authors.initials: T
authors.lastname: Ogura
authors.forename: H
authors.initials: H
authors.lastname: Niki
authors.forename: S
authors.initials: S
authors.lastname: Hiraga
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D008780:Methyltransferases / Q000235:genetics*; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D011401:Promoter Regions, Genetic / Q000235:genetics; D012436:S-Adenosylmethionine / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D001616:beta-Galactosidase / Q000378:metabolism
chemical_list: D004269:DNA, Bacterial; D012436:S-Adenosylmethionine; D008780:Methyltransferases; D001616:beta-Galactosidase