title: System considerations favoring rotary artificial hearts with blood-immersed bearings.
abstract: Hydrodynamic blood pumps provide such advantages as not requiring an air vent or compliance chamber as well as a great reduction in mechanical complexity with the potential for very long durability. The detailed design of their bearings is emerging as the single most important determinant of long-term success. Three categories of bearings include remote force, such as magnetic suspension; blood-isolated, which require a shaft seal; and blood-immersed using either mechanical or hydrodynamic support. Blood-immersed bearings permit maximum simplification and miniaturization of the entire system, require no flush fluid, and require no electronics as with magnetic suspension. The Jarvik 2000 heart represents an example of their potential. The intraventricular titanium pump (25 mm diameter, 25 cc, 85 g), uses blood flow through the motor air gap with blood-immersed bearings. The longest in vitro bearing durability test is ongoing at 20,000,000,000 revolutions with minimal wear (3 years at 15,000 rpm). In vivo results include 5-month calf survival, no thromboembolism, plasma Hb 2-5 mg%, and power under 10 W.
authors.affiliation: Jarvik Research, Inc., New York, New York 10023, USA.
authors.forename: R K
authors.initials: RK
authors.lastname: Jarvik
mesh_terms: D001783:Blood Flow Velocity; D004389:Durable Medical Equipment / Q000592:standards; D004574:Electromagnetic Fields; D006354:Heart, Artificial / Q000592:standards*; D006353:Heart-Assist Devices / Q000592:standards*; D006801:Humans; D014025:Titanium / Q000737:chemistry
chemical_list: D014025:Titanium