title: The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments.
abstract: Many bacterial pathogens and eukaryotic parasites can enter mammalian cells and live intracellularly inside membrane-bound vacuoles. The intravacuolar lifestyle of these pathogens plays a key role in pathogenesis. Understanding the molecular basis of the development of these specialized intracellular compartments is critical to understanding how these organisms cause disease.
authors.affiliation: Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa, Facultad de Biología, Universidad Autónoma de Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Garcia-del Portillo
authors.forename: B B
authors.initials: BB
authors.lastname: Finlay
mesh_terms: D000818:Animals; D018407:Bacterial Physiological Phenomena; D004912:Erythrocytes / Q000382:microbiology / Q000469:parasitology; D006790:Host-Parasite Interactions; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010271:Parasites / Q000502:physiology*; D010588:Phagosomes; D014617:Vacuoles / Q000382:microbiology* / Q000469:parasitology*