title: A novel site of DNA amplification on chromosome 1p32-33 in a rhabdomyosarcoma revealed by comparative genomic hybridization.
abstract: Cytogenetic analysis of a human embryonal rhabdomyosarcoma revealed a near-diploid karyotype with structural chromosome aberrations not involving the typical rearrangements of rhabdomyosarcomas, plus a large number of double minutes. Comparative genomic hybridization revealed a previously undescribed site of DNA amplification on the short arm of chromosome 1 (band 1p32-33).
authors.affiliation: Dep. of Neurosurgery, University Clinic, Homburg/Saar, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Steilen-Gimbel
authors.forename: K
authors.initials: K
authors.lastname: Remberger
authors.forename: N
authors.initials: N
authors.lastname: Graf
authors.forename: W I
authors.initials: WI
authors.lastname: Steudel
authors.forename: K D
authors.initials: KD
authors.lastname: Zang
authors.forename: W
authors.initials: W
authors.lastname: Henn
mesh_terms: D002648:Child; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D015342:DNA Probes; D004273:DNA, Neoplasm / Q000235:genetics*; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D019042:Muscle Neoplasms / Q000235:genetics* / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000235:genetics* / Q000473:pathology
chemical_list: D015342:DNA Probes; D004273:DNA, Neoplasm