[The emotive and cognitive reactions in temporary pharmacological menopause].
The authors have attempted to evaluate the extent to which menopausal crisis is linked to hypoestrogenism and the extent to which it is linked to the socioenvironmental context in which it takes place. The study analyses emotional and cognitive aspects in a group of women in temporary menopause which was pharmacologically induced for therapeutic purposes. The study was carried out in 30 patients suffering from benign gynecological pathologies receiving ovarian steroidogenesis-blocking treatment. Treatment consisted of a subcutaneous administration of a Gn-Rh analog every 28 days for 6 months. After having collected information regarding the symptoms that appeared following the administration of therapy, the authors evaluated the emotive (anxiety and depression) and cognitive (short-term memory and concentration) conditions of patients using psychometric reactives performed during the first check-up, and then repeated at the 3rd, 5th and 7th control visit: the State-Trait-Anxiety-Inventory to assess trait anxiety and state anxiety; scale D of the Minnesota Multiphasic Personality Inventory to assess depression; the sub-test for memory of figures from Wechsler-Bellevue Intelligence Scale to evaluate short-term memory; the Toulouse-Pieron reactive to evaluate attention and concentration. The results obtained were analysed statistically using Student's t-test and Pearson's coefficient. An analysis of the data shows that, after the first doses of the drug stress trends to diminish from the high levels recorded at the first visit, stabilising at normal values throughout treatment. Like anxiety and depression, concentration and memory do not show marked variations.(ABSTRACT TRUNCATED AT 250 WORDS)
Giusto
M D
MD
Università degli Studi di Roma La Sapienza, Dipartimento di Scienze Psichiatriche e Medicina Psicologica.
Lambiasi
A
A
Cantonetti
G
G
Morini
A
A
D000328:Adult; D003071:Cognition; D003692:Delayed-Action Preparations; D004644:Emotions; D005260:Female; D005831:Genital Diseases, Female / Q000523:psychology; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists; D017273:Goserelin / Q000008:administration & dosage; D006801:Humans; D007406:Interview, Psychological; D008950:MMPI; D008593:Menopause / Q000187:drug effects* / Q000523:psychology*; D011594:Psychometrics; D013997:Time Factors; D014888:Wechsler Scales
D003692:Delayed-Action Preparations; D017273:Goserelin; D007987:Gonadotropin-Releasing Hormone
Reazioni emotivo-cognitive in menopausa farmacologica temporanea.