title: Morphological and histochemical changes in the liver and pancreas of gilthead, Sparus auratus L., induced by acute action of the anionic detergent, sodium dodecyl sulphate.
abstract: This paper reports the morphological and histochemical changes in the livers and pancreas of giltheads (Sparus auratus, L.) induced by acute action of the anionic detergent, sodium dodecyl sulphate (SDS). Sixty-five giltheads were exposed to SDS concentrations of 5, 8.5, 10 and 15 mg/l. The surface tension induced at each concentration was determined and the LC50 calculated. Morphological changes dependent on detergent concentrations and length of exposure were seen. Histochemical techniques showed alterations in carbohydrates and proteins, which may interfere with liver and pancreas function.
authors.affiliation: Department of Morphological Sciences, Faculty of Medicine, University of Cádiz, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Ribelles
authors.forename: M C
authors.initials: MC
authors.lastname: Carrasco
authors.forename: M
authors.initials: M
authors.lastname: Rosety
authors.forename: M
authors.initials: M
authors.lastname: Aldana
mesh_terms: D000818:Animals; D050260:Carbohydrate Metabolism; D004305:Dose-Response Relationship, Drug; D006651:Histocytochemistry; D007928:Lethal Dose 50; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D010179:Pancreas / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D010473:Perciformes; D011506:Proteins / Q000378:metabolism; D012967:Sodium Dodecyl Sulfate / Q000633:toxicity*; D013500:Surface Tension; D013501:Surface-Active Agents / Q000633:toxicity*
chemical_list: D011506:Proteins; D013501:Surface-Active Agents; D012967:Sodium Dodecyl Sulfate