title: Red cell 6-phosphogluconate dehydrogenase polymorphism in the Gadaba of Andhra Pradesh (India). Report of new variant phenotypes.
abstract: Blood samples from 1000 unrelated, adult individuals of the Gadaba tribal population were screened for 6-phosphogluconate dehydrogenase. We report the occurrence of a new fast moving variant, which is caused by the allele PGD* Gadaba. This allele is reported for the first time among the tribal populations of Andhra Pradesh. Its frequency comes to 0.0115, and it was observed in heterozygous (2.10%) and homozygous (0.10%) conditions.
authors.affiliation: Department of Anthropology, Government Degree College, Srikakulam, India.
authors.forename: P M
authors.initials: PM
authors.lastname: Rao
authors.forename: R L
authors.initials: RL
authors.lastname: Kirk
authors.forename: B R
authors.initials: BR
authors.lastname: Busi
authors.forename: G G
authors.initials: GG
authors.lastname: Reddi
authors.forename: G V
authors.initials: GV
authors.lastname: Ramana
mesh_terms: D000328:Adult; D000483:Alleles; D003906:Developing Countries; D004912:Erythrocytes / Q000201:enzymology*; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D014644:Genetic Variation; D005828:Genetics, Population; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007194:India; D008297:Male; D010641:Phenotype; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics*
chemical_list: D010734:Phosphogluconate Dehydrogenase