Immunosuppressive peptides corresponding to MHC class I sequences.
The induction of tolerance is a long-standing goal in transplantation. Intact MHC molecules, or fragments of them, are being used to render T cells unresponsive both in vitro and in vivo. Elucidation of the mechanisms underlying the effects of these treatments should aid the design of novel therapies for transplantation.
Clayberger
C
C
Department of Cardiothoracic Surgery, Stanford University, CA 94305-5247, USA.
Krensky
A M
AM
D003460:Crystallization; D015395:Histocompatibility Antigens Class I / Q000737:chemistry* / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000138:chemical synthesis / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*
D015395:Histocompatibility Antigens Class I; D007166:Immunosuppressive Agents; D010455:Peptides; C092373:allotrap