title: Teflon granuloma presenting as an enlarging, gadolinium enhancing, posterior fossa mass with progressive hearing loss following microvascular decompression.
abstract: Deleterious effects of Teflon strand placement during microvascular decompression (MVD) for hemifacial spasm are rare. In this report, a patient who had previously undergone suboccipital MVD for hemifacial spasm presented 3 years postoperatively with a progressive asymmetric sensorineural hearing loss and magnetic resonance imaging evidence of an enlarging ipsilateral gadolinium enhancing 1-cm cerebellopontine angle lesion. At surgery a granuloma was found displacing the structures of the internal auditory canal. Histologically, evidence of a Teflon fiber-induced giant cell granuloma was identified. This paper reviews the literature of Teflon-induced histopathology as it relates to posterior fossa MVD surgery, as well as its relation to this previously unreported complication.
authors.affiliation: Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Megerian
authors.forename: N Y
authors.initials: NY
authors.lastname: Busaba
authors.forename: M J
authors.initials: MJ
authors.lastname: McKenna
authors.forename: R G
authors.initials: RG
authors.lastname: Ojemann
mesh_terms: D000368:Aged; D003388:Cranial Fossa, Posterior / Q000473:pathology*; D003937:Diagnosis, Differential; D005154:Facial Nerve / Q000098:blood supply / Q000601:surgery; D005260:Female; D005682:Gadolinium; D015745:Granuloma, Foreign-Body / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D006101:Granuloma, Giant Cell / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D008833:Microcirculation / Q000601:surgery; D009408:Nerve Compression Syndromes / Q000601:surgery; D011138:Polytetrafluoroethylene / Q000009:adverse effects*; D011183:Postoperative Complications / Q000209:etiology*; D013035:Spasm / Q000601:surgery
chemical_list: D011138:Polytetrafluoroethylene; D005682:Gadolinium