title: Thrombin functions and antithrombotic intervention.
authors.affiliation: New York State Department of Health, Wadsworth Center for Laboratories and Research, Albany 12201, USA.
authors.forename: J W
authors.initials: JW
authors.lastname: Fenton
mesh_terms: D000590:Amino Acid Chloromethyl Ketones / Q000494:pharmacology; D000595:Amino Acid Sequence; D000818:Animals; D000991:Antithrombins / Q000627:therapeutic use*; D001777:Blood Coagulation / Q000502:physiology; D006224:Cricetinae; D024764:Hirudin Therapy; D006629:Hirudins / Q000031:analogs & derivatives; D051379:Mice; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000627:therapeutic use; D051381:Rats; D018179:Receptors, Thrombin / Q000737:chemistry / Q000378:metabolism; D011994:Recombinant Proteins / Q000627:therapeutic use; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D013379:Substrate Specificity; D013917:Thrombin / Q000302:isolation & purification / Q000502:physiology*; D013927:Thrombosis / Q000188:drug therapy* / Q000517:prevention & control
chemical_list: D000590:Amino Acid Chloromethyl Ketones; D000991:Antithrombins; D006629:Hirudins; D010446:Peptide Fragments; D018179:Receptors, Thrombin; D011994:Recombinant Proteins; D013917:Thrombin; C040308:phenylalanyl-prolyl-arginine-chloromethyl ketone; C074619:bivalirudin