Typing and grading breast carcinoma on fine-needle aspiration: is this clinically useful information?
The ability of fine-needle aspiration (FNA) to diagnose breast cancer is beyond question. The established role of cytopathology is to maintain a low benign to malignant biopsy ratio by reducing the number of benign lesions excised. Both typing and grading of breast cancers on FNA have received attention in the cytology literature but how this knowledge can influence management has not been fully explored. Recently we described a method for the cytological grading of breast cancer that compares well with the established Bloom and Richardson grades. In this paper we present our experience of 1,387 breast cancer FNAs reported by us with histological verification. We show that cytologically typing and grading breast cancers are valid exercises that can predict the true nature of the neoplasm. This information may assist in the clinical approach to the malignant breast.
Robinson
I A
IA
Department of Cytopathology, Royal-Surrey County Hospital, Guildford, United Kingdom.
McKee
G
G
Kissin
M W
MW
D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000145:classification / Q000473:pathology* / Q000628:therapy; D002277:Carcinoma / Q000145:classification / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity