title: [Nerve-neuroendocrine complexes in stomach mucosa in Zollinger-Ellison syndrome].
abstract: Nerve fibre-neuroendocrine cell complexes (NF-NEC-C's) are neuroendocrine cells located in the lamina propria of the gastro-intestinal tract directly connected with nerve fibres of Meissner's plexus. We report on a patient with sporadic Zollinger-Ellison syndrome (ZES) with electron microscopically demonstrated multiple NF-NEC-C's in non-antral gastric mucosa. It is suspected that in ZES the hypergastrinaemia may represent a trophic stimulus for the proliferation of NF-NEC-C's in the gastric mucosa.
authors.affiliation: Medizinische Klinik I, Universität Erlangen-Nürnberg.
authors.forename: H G
authors.initials: HG
authors.lastname: Schmidt
authors.forename: A
authors.initials: A
authors.lastname: Schmid
authors.forename: W
authors.initials: W
authors.lastname: Domschke
mesh_terms: D000328:Adult; D001369:Axons / Q000473:pathology; D001485:Basement Membrane / Q000473:pathology; D002455:Cell Division / Q000502:physiology; D003594:Cytoplasmic Granules / Q000473:pathology; D005753:Gastric Mucosa / Q000294:innervation*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000473:pathology*; D009490:Neurosecretory Systems / Q000473:pathology*; D013368:Submucous Plexus / Q000473:pathology*; D015043:Zollinger-Ellison Syndrome / Q000473:pathology*
vernacular_title: Nerval-Neuroendokrine Komplexe in Magenschleimhaut bei Zollinger-Ellison-Syndrom.