Cryptococcal meningitis and confusional psychosis. A case report and literature review.
A previously healthy and immuno-competent 22-year-old man presented in confusional psychosis. Cryptococcal meningitis was later found to be the underlying cause as proven by culturing Cryptococcus neoformans serotype A from the cerebrospinal fluid. Combined antifungal therapy with amphotericin B and 5-fluorocytosine resulted in sustained improvement of all mental and physical functions. Cryptococcosis has rarely been reported from the Middle East. This represents the second case from Kuwait.
Sa'adah
M A
MA
Medical Department, Islamic Hospital, Amman, Jordan.
Araj
G F
GF
Diab
S M
SM
Nazzal
M
M
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D003221:Confusion / Q000188:drug therapy / Q000209:etiology*; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D016919:Meningitis, Cryptococcal / Q000150:complications* / Q000188:drug therapy; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000209:etiology*
D000666:Amphotericin B; D005437:Flucytosine