title: Hospital charges for conventional therapy versus left ventricular assist system therapy in heart transplant patients.
abstract: An important goal of a left ventricular assist system (LVAS) is to provide long-term, safe, cost-effective mechanical circulatory support. The Heartmate LVAS (Thermo Cardiosystems, Inc., Woburn, MA), used in recent clinical trials as a bridge to transplantation, has proven extremely reliable for long periods, and its use has improved the survival rates in patients who subsequently received a donor heart. Patients who have been implanted with an LVAS often have significantly improved physical status and can leave the intensive care unit (ICU) and be treated at less expense elsewhere in the hospital. In this preliminary report, the authors analyzed hospital charges for three groups of patients: heart transplant patients who received conventional medical therapy before transplantation (Group 1), transplant patients who received in-hospital LVAS therapy (Group 2), and one patient who awaited transplantation at home while undergoing LVAS support. Group 1 patients (n = 6) received intraaortic balloon pump (IABP) support and inotropic therapy in an ICU before transplantation. Group 2 (n = 6) patients were receiving IABP support and inotropic therapy when the LVAS was implanted and eventually underwent heart transplantation. The length of hospital stay in Group 1 (51 days) was significantly shorter than in Group 2 (185 days). Mean hospital charge in Group 1 was $5,150/day; in Group 2, $3,178/day. The patient living at home incurred an average medical expense of $27/day. Although LVAS supported patients remain in the hospital much longer than do medically treated patients, their average daily in-hospital charges are much less. If the LVAS could be used as an alternative to transplantation, it might offer not only a longer, better quality life, but also a potential cost savings to patients with end-stage heart failure.
authors.affiliation: Cullen Cardiovascular Research Laboratories, Department of Cardiovascular Surgical Research, Texas Heart Institute, Houston 77030, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Cloy
authors.forename: T J
authors.initials: TJ
authors.lastname: Myers
authors.forename: L A
authors.initials: LA
authors.lastname: Stutts
authors.forename: M P
authors.initials: MP
authors.lastname: Macris
authors.forename: O H
authors.initials: OH
authors.lastname: Frazier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care / Q000191:economics; D009202:Cardiomyopathies / Q000191:economics / Q000601:surgery / Q000628:therapy; D004867:Equipment Design; D005260:Female; D016027:Heart Transplantation / Q000191:economics*; D006353:Heart-Assist Devices / Q000191:economics*; D017722:Hospital Charges / Q000706:statistics & numerical data*; D006801:Humans; D007423:Intra-Aortic Balloon Pumping / Q000191:economics; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D014481:United States