title: Mohs' micrographic surgery and distal urethrectomy with immediate urethral reconstruction for glanular carcinoma in situ with significant urethral extension.
abstract: OBJECTIVE
  To report the use of conservative extirpative surgical techniques to manage glanular carcinoma in situ with significant urethral extension.
  
  
  METHODS
  Over a 5-year period, 2 patients with carcinoma in situ of the glans with significant distal urethral involvement, who refused penectomy, were managed with combined treatment modalities using Mohs' micrographic surgery and distal urethrectomy with immediate urethral reconstruction.
  
  
  RESULTS
  At follow-up of 5 years and of 12 months, there has been no evidence of meatal or proximal urethral recurrence.
  
  
  CONCLUSIONS
  Mohs' micrographic surgical excision and distal urethrectomy with immediate urethral reconstruction offers an acceptable alternative to partial penectomy in patients with perimeatal carcinoma in situ who fail conservative treatment or refuse penectomy.
authors.affiliation: Department of Urology, Indiana University Medical Center, Indianapolis 46202-5265, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Nash
authors.forename: R
authors.initials: R
authors.lastname: Bihrle
authors.forename: P E
authors.initials: PE
authors.lastname: Gleason
authors.forename: M C
authors.initials: MC
authors.lastname: Adams
authors.forename: C W
authors.initials: CW
authors.lastname: Hanke
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D009378:Neoplasms, Multiple Primary / Q000601:surgery*; D010412:Penile Neoplasms / Q000601:surgery*; D014521:Urethra / Q000601:surgery*; D014523:Urethral Neoplasms / Q000601:surgery*