Wegener's granulomatosis complicated by arterial aneurysm.
Wegener's granulomatosis is a distinct clinicopathologic entity characterized by granulomatous vasculitis of the upper and lower respiratory tract and kidneys. A 56-year-old Japanese man with Wegener's granulomatosis died of intraperitoneal hemorrhage from a ruptured aneurysm of his left gastric artery. Histological findings revealed necrotizing granulomatous vasculitis involving this artery. No previously published reports have described Wegener's granulomatosis patients with aneurysms in such a large artery. We conclude that this case represents either an atypical form of Wegener's granulomatosis or a polyangiitis overlap syndrome of Wegener's granulomatosis and classic polyarteritis nodosa.
Aoki
N
N
Department of Emergency and Critical Care Medicine, Kitasato University School of Medicine, Kanagawa.
Soma
K
K
Owada
T
T
Ishii
H
H
D000783:Aneurysm / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous; D013270:Stomach / Q000098:blood supply* / Q000473:pathology