title: The use of ultrasound in the non-invasive detection of changes in the renal circulation in response to blood loss using an animal model.
abstract: Using a continuous haemorrhage model, 8 anaesthetised swine were bled 1 ml/kg per min for 30 min. The resistance index (RI) of the main renal artery, interlobar and arcuate vessels all significantly increased. Cortical Doppler signals were lost in 4 animals at a mean arterial pressure of 26 mmHg. After reinfusion of blood and normal saline only the RI of the interlobar vessels was significantly different from baseline readings. Ultrasound demonstrated non-invasively changes in regional blood flow within the kidney in response to hypovolaemic shock.
authors.affiliation: Accident and Emergency Department, Bristol Royal Infirmary, Avon, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Clancy
authors.forename: J
authors.initials: J
authors.lastname: Alderman
authors.forename: C
authors.initials: C
authors.lastname: Case
authors.forename: K J
authors.initials: KJ
authors.lastname: Taylor
mesh_terms: D000818:Animals; D001794:Blood Pressure; D001803:Blood Transfusion; D002302:Cardiac Output; D004195:Disease Models, Animal; D005260:Female; D006339:Heart Rate; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000503:physiopathology*; D007672:Kidney Cortex / Q000098:blood supply / Q000000981:diagnostic imaging; D012039:Regional Blood Flow; D012077:Renal Artery / Q000000981:diagnostic imaging; D012079:Renal Circulation; D012769:Shock / Q000000981:diagnostic imaging / Q000503:physiopathology; D012771:Shock, Hemorrhagic / Q000000981:diagnostic imaging / Q000503:physiopathology; D012965:Sodium Chloride; D013552:Swine; D018608:Ultrasonography, Doppler; D018615:Ultrasonography, Doppler, Color; D018617:Ultrasonography, Doppler, Pulsed; D014655:Vascular Resistance
chemical_list: D012965:Sodium Chloride