title: Hepatitis C virus quasispecies populations during chronic hepatitis C infection.
abstract: Hepatitis C virus populations in infected individuals consist of quasispecies with diverse mutations. These quasispecies have different biological properties, and the analysis of these variants has led to new interpretations of viral persistence, carcinogenesis and resistance to interferon therapy.
authors.affiliation: Second Dept of Internal Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Enomoto
authors.forename: C
authors.initials: C
authors.lastname: Sato
mesh_terms: D000595:Amino Acid Sequence; D002908:Chronic Disease; D004352:Drug Resistance, Microbial; D016174:Hepacivirus / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D006526:Hepatitis C / Q000188:drug therapy / Q000821:virology*; D006801:Humans; D007372:Interferons / Q000494:pharmacology; D008969:Molecular Sequence Data; D013045:Species Specificity
chemical_list: D007372:Interferons