Comparison of long-term efficacy of medical treatment versus percutaneous transluminal coronary angioplasty (PTCA) in single-vessel disease.
The long-term outcome of PTCA and medical therapy were compared in patients with SVD. All patients were confirmed to have > or - 75% stenosis of a major coronary artery by coronary arteriogram. The 5-year survival rates were 96.0% for medical therapy and 98.9% for successful angioplasty. Both therapies achieved an equally good long-term outcome for SVD. The incidence of nonfatal cardiac events during follow-up was higher in patients treated by PTCA than in those on medical therapy, but there was no difference between the two groups in the incidence of nonfatal MI at 5 years (2.5% vs 1.8%). The most common cardiac event in patients undergoing successful PTCA was repeat intervention associated with restenosis. In view of the long-term efficacy of PTCA, the high restenosis rate remains an important problem and it is necessary to elucidate the causes of restenosis and develop countermeasures as soon as possible.
Nishiyama
S
S
Cardiovascular Center, Division of Cardiology, Toranomon Hospital, Tokyo, Japan.
Iwase
T
T
Ishiwata
S
S
Komiyama
N
N
Yanagishita
Y
Y
Nakanishi
S
S
Seki
A
A
D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003251:Constriction, Pathologic / Q000188:drug therapy / Q000401:mortality / Q000628:therapy; D003327:Coronary Disease / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome