title: Commonly used diagnostic criteria for pelvic inflammatory disease have poor sensitivity for plasma cell endometritis.
abstract: BACKGROUND
  The majority of women with tubal damage do not have a history of acute pelvic inflammatory disease. The prevalence of upper genital tract inflammation was evaluated in women deemed not to have pelvic inflammatory disease by common diagnostic criteria.
  
  
  OBJECTIVE
  To compare clinical signs and laboratory tests used to diagnose pelvic inflammatory disease with endometrial biopsy histopathology.
  
  
  METHODS
  Endometrial biopsy and commonly used physical and laboratory tests were performed on 52 women with pelvic tenderness, 51 with vaginosis or cervicitis, and 22 control subjects who had no evidence of infection with Neisseria gonorrhoeae or Chlamydia trachomatis and who tested negative for bacterial vaginosis using vaginal swab Gram's stain.
  
  
  RESULTS
  Thirty-six of 52 patients (69%) with pelvic tenderness, compared with 22 of 51 patients (43%) with vaginosis or cervicitis and two of 22 control subjects (9%), had plasma cell endometritis. The Centers for Disease Control and Prevention minimal diagnostic criteria for pelvic inflammatory disease had a sensitivity of 33% for plasma cell endometritis.
  
  
  CONCLUSIONS
  The clinical diagnosis of pelvic inflammatory disease using published criteria correlates poorly with plasma cell endometritis.
authors.affiliation: Department of Obstetrics, Gynecology, University of California, San Francisco, USA.
authors.forename: A P
authors.initials: AP
authors.lastname: Korn
authors.forename: N
authors.initials: N
authors.lastname: Hessol
authors.forename: N
authors.initials: N
authors.lastname: Padian
authors.forename: G
authors.initials: G
authors.lastname: Bolan
authors.forename: D
authors.initials: D
authors.lastname: Muzsnai
authors.forename: E
authors.initials: E
authors.lastname: Donegan
authors.forename: J
authors.initials: J
authors.lastname: Jonte
authors.forename: J
authors.initials: J
authors.lastname: Schachter
authors.forename: D V
authors.initials: DV
authors.lastname: Landers
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D016022:Case-Control Studies; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis; D004716:Endometritis / Q000382:microbiology / Q000473:pathology*; D005260:Female; D006069:Gonorrhea / Q000150:complications*; D006801:Humans; D000292:Pelvic Inflammatory Disease / Q000382:microbiology / Q000473:pathology*; D010950:Plasma Cells / Q000473:pathology*; D012680:Sensitivity and Specificity; D002575:Uterine Cervicitis / Q000473:pathology; D016585:Vaginosis, Bacterial / Q000473:pathology