Chemical and biological properties of cytotoxic alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazones.
Liu
M C
MC
Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520, USA.
Lin
T S
TS
Sartorelli
A C
AC
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry*; D006801:Humans; D007938:Leukemia / Q000188:drug therapy; D051379:Mice; D012262:Ribonucleoside Diphosphate Reductase / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D013882:Thiosemicarbazones / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use
D000970:Antineoplastic Agents; D013882:Thiosemicarbazones; C002526:1-formylisoquinoline thiosemicarbazone; C013996:2-formylpyridine thiosemicarbazone; D012262:Ribonucleoside Diphosphate Reductase