title: A new antiherpetic agent produced by Streptomyces sp. strain no. 758.
abstract: A new antiherpetic agent, AH-758, was isolated from the culture broth of Streptomyces sp. strain No. 758. The structure was determined by NMR special analyses to be a new antibiotic belonging to bafilomycin group containing (5-oxo-2-pyrrolin-2-yl) methyl fumarate in its C-21.
authors.affiliation: Faculty of Pharmaceutical Sciences, Kumamoto University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Uyeda
authors.forename: K I
authors.initials: KI
authors.lastname: Kondo
authors.forename: A
authors.initials: A
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Yokomizo
authors.forename: Y
authors.initials: Y
authors.lastname: Kido
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D017077:Culture Media, Conditioned; D006094:Gram-Positive Bacteria / Q000187:drug effects; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013302:Streptomyces / Q000145:classification / Q000378:metabolism*
chemical_list: C097817:AH 758; D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D017077:Culture Media, Conditioned; D018942:Macrolides