title: Thioesterase and protein deacylase activities of porcine pancreatic phospholipase A2.
abstract: The thioesterase activity of porcine pancreatic phospholipase A2 has been investigated with non-phospholipid substrates. The acyl-CoA hydrolase activity towards acyl-CoA derivatives is specific for long chain fatty acids (14 C, 16 C) but is unable to hydrolyze short chain acyl-CoA compounds (below 8 C). The same enzyme also shows protein deacylase activity liberating [3H]palmitic acid from [3H]palmitoyl-acyl carrier protein.
authors.affiliation: Department of Immunology, Hospital Ramón y Cajal, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Nocito
authors.forename: G
authors.initials: G
authors.lastname: Roy
authors.forename: L M
authors.initials: LM
authors.lastname: Villar
authors.forename: C
authors.initials: C
authors.lastname: Palacios
authors.forename: A
authors.initials: A
authors.lastname: Serrano
authors.forename: J C
authors.initials: JC
authors.lastname: Alvarez-Cermeño
authors.forename: P
authors.initials: P
authors.lastname: González-Porqué
mesh_terms: D000217:Acyltransferases / Q000378:metabolism*; D000818:Animals; D010170:Palmitoyl-CoA Hydrolase / Q000378:metabolism; D010179:Pancreas / Q000201:enzymology*; D010741:Phospholipases A / Q000378:metabolism*; D054467:Phospholipases A2; D013552:Swine; D013869:Thiolester Hydrolases / Q000378:metabolism*
chemical_list: D000217:Acyltransferases; C065617:acyl carrier protein acylase; D010741:Phospholipases A; D054467:Phospholipases A2; D013869:Thiolester Hydrolases; D010170:Palmitoyl-CoA Hydrolase