title: [The dissolution of cystine lithiasis with n-acetylcysteine].
abstract: OBJECTIVE
  The results of in situ dissolution of a cystine calculus is described. This approach was attempted in a female patient for whom surgery was not considered to be the best therapeutic option.
  
  
  METHODS
  An obstructive cystine calculus was treated by in situ litholysis using N-acetylcysteine applied locally via two percutaneous nephrostomies and adjuvant oral metaphylaxis. The patient had a long clinical history of lithiasis that had also required surgery and a family history of cystinuria.
  
  
  RESULTS
  In situ litholysis completely dissolved the cystine calculus and avoided the need for a complex surgery. The procedure and a pharmacological analysis are presented.
  
  
  CONCLUSIONS
  In our view, this procedure is practical, carries minimal morbidity and should be considered in the management of cystine calculus.
authors.affiliation: Servicio de Urología, Hospital Na. Sra. Alarcos, Ciudad Real, España.
authors.forename: J
authors.initials: J
authors.lastname: Benítez Navio
authors.forename: P
authors.initials: P
authors.lastname: Tudela Pavón
authors.forename: G
authors.initials: G
authors.lastname: Laguna Urraca
authors.forename: T
authors.initials: T
authors.lastname: Casanueva Luis
authors.forename: M
authors.initials: M
authors.lastname: Ruana Encinar
authors.forename: F
authors.initials: F
authors.lastname: Mata Guijarro
authors.forename: C
authors.initials: C
authors.lastname: Gallardo Galán
mesh_terms: D000111:Acetylcysteine / Q000008:administration & dosage*; D000328:Adult; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003553:Cystine / Q000032:analysis*; D003555:Cystinuria / Q000235:genetics / Q000628:therapy; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000737:chemistry / Q000628:therapy*; D012074:Remission Induction; D012996:Solutions; D013997:Time Factors
chemical_list: D012996:Solutions; D003553:Cystine; D000111:Acetylcysteine
vernacular_title: Disolución de una litiasis cistínica con n-acetilcisteína.