Factors which influence levels of selected organisms in saliva of older individuals.
The most commonly measured bacterial parameters in saliva are the levels of the mutans group streptococci and lactobacilli, which have diagnostic implications for the incidence of dental decay. Diagnostic guidelines which are applicable to children and young adults in whom most, if not all, teeth are present and in whom the rate of stimulated saliva is almost always greater than 0.5 ml/min have been developed. Dental decay is a potential health problem of considerable magnitude among elderly individuals. In elderly individuals, missing teeth, the presence of dentures, and a reduced salivary flow could confound the interpretation of salivary levels of cariogenic bacteria. In the present study, in which saliva was collected from more than 560 elderly individuals (average age, 70 +/- 8 years), there was a significant positive relationship between the salivary levels of Streptococcus mutans and increased numbers of teeth. There was a positive association between the salivary levels of S. mutans and decay when the data were stratified for the presence of a complaint of xerostomia and the presence of dentures. However, a similar analysis indicated that lactobacilli and yeasts were more likely to be associated with decay. The various variables which could influence the bacterial counts per milliliter of saliva, e.g., independent or dependent living status, complaint of xerostomia, stimulated salivary flow, salivary pH, the presence of dentures, number of teeth, and decay, were analyzed simultaneously by using a multivariable linear model. In that analysis the number of decayed teeth was significantly associated with the presence of lactobacilli (P = 0.0001) and yeasts (P = 0.025) but not with the presence of S. mutans. Our findings indicate that salivary levels of lactobacilli and yeasts, as well as the salivary levels of S. mutans, should be monitored when seeking microbial indicators that might predict the incidence of caries in elderly individuals.
Loesche
W J
WJ
School of Denistry, University of Michigan, Ann Arbor 48109-1078, USA.
Schork
A
A
Terpenning
M S
MS
Chen
Y M
YM
Stoll
J
J
D000203:Activities of Daily Living; D000368:Aged; D000375:Aging; D003731:Dental Caries; D003778:Dentures; D006094:Gram-Positive Bacteria / Q000302:isolation & purification*; D006801:Humans; D007576:Jaw, Edentulous, Partially; D007778:Lactobacillus / Q000302:isolation & purification; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism / Q000382:microbiology*; D013291:Streptococcus / Q000302:isolation & purification; D014987:Xerostomia; D015003:Yeasts / Q000302:isolation & purification*