title: [Parkinsonism induced by sodium valproate].
abstract: Parkinsonism is a rare side effect of treatment with sodium valproate. We report 2 elderly women who developed parkinsonian syndrome several years after starting valproate therapy, and in whom symptoms disappeared when treatment was withdrawn. These cases, along with others in the literature, may support experimental evidence for the importance of GABAergic modulation in motor control.
authors.affiliation: Servicio de Neurología, Complejo Hospitalario de Ciudad Real.
authors.forename: M A
authors.initials: MA
authors.lastname: del Real Francia
authors.forename: J
authors.initials: J
authors.lastname: Sanz Martínez
authors.forename: J
authors.initials: J
authors.lastname: Vaamonde Gamo
authors.forename: M
authors.initials: M
authors.lastname: Gudín Rodríguez-Magariños
authors.forename: R
authors.initials: R
authors.lastname: Ibáñez Alonso
authors.forename: V
authors.initials: V
authors.lastname: Riñón
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy; D005260:Female; D006801:Humans; D010300:Parkinson Disease / Q000209:etiology*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D014635:Valproic Acid
vernacular_title: Síndrome parkinsoniano inducido por valproato sódico.