[Incidence of ovarian hyperstimulation syndrome in in-vitro-fertilization treatment over a period of 11 years].
A total of 2915 cycles of controlled ovarian hyperstimulation (COH) were performed from 1981 to 1992 in an in-vitro fertilization--embryo transfer (IVFET) programme at our institute. In 325 (11.2%) cycles an ovarian hyperstimulation syndrome (OHSS) developed. It was defined if more than 10 follicles with a size of > 15 mm were found on the day of follicle puncture. OHSS was found to be more frequent in the 3rd quarter of the years. Soltriol or melatonin may play a role in this context. Additionally, we were able to confirm some risk factors that were previously reported to be associated with the OHSS: use of gonadotropin-releasing hormone agonist (GnRHa) protocols, and young age (< 35 years). The pregnancy rate was found to be higher among OHSS cases.
Niederberger
V
V
II. Universitäts-Frauenklinik, Universität Wien.
Rottensteiner-Grohsmann
C
C
Turnheim
K
K
Obruca
A
A
Brunner
M
M
Feichtinger
W
W
D000328:Adult; D001317:Austria / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004624:Embryo Transfer / Q000706:statistics & numerical data*; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D016471:Ovarian Hyperstimulation Syndrome / Q000453:epidemiology* / Q000209:etiology; D011247:Pregnancy; D012307:Risk Factors; D012621:Seasons; D016896:Treatment Outcome
Beobachtungen zum Auftreten des ovariellen Uberstimulationssyndroms bei der Behandlung mit In-vitro-Fertilisation in einem Zeitraum von 11 Jahren.