On age-related changes of cell membrane permeability in human buccal epithelium cells.
An original method for the determination of cell membrane permeability has been developed. Human buccal epithelium cells were treated with Indigo Carmine and the percentage of stained cells was determined. Employing this method, the age-related differences in properties of plasma membrane in cells of human buccal epithelium were demonstrated. In the group of aged donors the average level of cell stainability was higher than in the group of younger donors. These results demonstrate a decrease in outer cell membrane integrity with age.
Shckorbatov
Y G
YG
Institute of Biology, Kharkov State University, Ukraine.
Shakhbazov
V G
VG
Bogoslavsky
A M
AM
Rudenko
A O
AO
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000502:physiology*; D004848:Epithelium / Q000378:metabolism; D004928:Escin / Q000493:pharmacokinetics; D006801:Humans; D008875:Middle Aged; D009061:Mouth Mucosa / Q000166:cytology / Q000378:metabolism*
D004928:Escin