The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones.
Willson
T M
TM
Glaxo Wellcome Research and Development, Research Triangle Park, North Carolina 27709, USA.
Cobb
J E
JE
Cowan
D J
DJ
Wiethe
R W
RW
Correa
I D
ID
Prakash
S R
SR
Beck
K D
KD
Moore
L B
LB
Kliewer
S A
SA
Lehmann
J M
JM
D000818:Animals; D002460:Cell Line; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology*; D051379:Mice; D018160:Receptors, Cytoplasmic and Nuclear / Q000819:agonists*; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000737:chemistry* / Q000494:pharmacology*; D014157:Transcription Factors / Q000819:agonists*
D007004:Hypoglycemic Agents; D018160:Receptors, Cytoplasmic and Nuclear; D013844:Thiazoles; D014157:Transcription Factors