[Control of ovulation in the mare with Ovuplant (short-term release of the GnRH analog deslorelin acetate). Overview of investigations from 1990 to 1994].
Ovuplant (deslorelin STI), when used in estrous mares with a follicle > or = 30 mm, reliably causes acceleration of ovulation and assurance that > 80% of the treated mares will ovulate within 48 hours. Time to ovulation is reduced by 30 hours or more. Treatment with Ovuplant had no adverse effects on pregnancy rates and did not increase the rate of early twin pregnancies. Treatment did not cause local or systemic side effects beyond short-term local irritation. Mares can be treated repeatedly without the development of tolerance or the loss of effectiveness. These studies have shown that Ovuplant can be used with a high level of assurance for success in the equine breeding industry. This will allow to reap benefits by reducing the number of breedings, saving stallion power and avoiding unnecessary inseminations. The mare has come an important step closer to a safe and effective management of ovulation.
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D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004343:Drug Implants; D004971:Estrus; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D006736:Horses; D007315:Insemination, Artificial / Q000662:veterinary; D008297:Male; D010060:Ovulation / Q000187:drug effects*; D011247:Pregnancy; D011270:Pregnancy, Animal; D017329:Triptorelin Pamoate / Q000031:analogs & derivatives
D006063:Chorionic Gonadotropin; D004343:Drug Implants; D017329:Triptorelin Pamoate; D007987:Gonadotropin-Releasing Hormone; C066438:deslorelin
Ovulationskontrolle bei der Stute mit Ovuplant (Kurzzeit-Freisetzung des GnRH-Analogs Deslorelinazetat). Ubersicht über Untersuchungen von 1990 bis 1994.