Imaging of post-transplant spindle cell tumors.
Spindle/smooth muscle cell proliferation is an additional neoplastic process related to immunosuppression and EBV infection. We describe four post transplant children with this diagnosis. Multiple organ systems may be involved, particularly the liver, gastrointestinal tract, and lungs. Lesions are radiographically, clinically, and endoscopically indistinguishable from those of post-transplant lymphoproliferative disease (PTLD).
Pollock
A N
AN
Department of Radiology, Children's Hospital of Pittsburgh, 3705 Fifth Avenue at De Soto Street Pittsburgh, PA 15213, USA.
Newman
B
B
Putnam
P E
PE
Dickman
P S
PS
Medina
J L
JL
D002648:Child; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007421:Intestine, Small / Q000637:transplantation; D016031:Liver Transplantation; D008232:Lymphoproliferative Disorders / Q000175:diagnosis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000821:virology; D011183:Postoperative Complications / Q000175:diagnosis* / Q000821:virology; D018235:Smooth Muscle Tumor / Q000175:diagnosis* / Q000821:virology; D014412:Tumor Virus Infections / Q000175:diagnosis*