title: Signal transduction of beta-catenin.
abstract: Beta-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus. The adenomatous polyposis coli tumor suppressor protein is also implicated in beta-catenin signaling.
authors.affiliation: Cellular Biochemistry & Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
authors.forename: B M
authors.initials: BM
authors.lastname: Gumbiner
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D003598:Cytoskeletal Proteins / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D015534:Trans-Activators; D051176:beta Catenin
chemical_list: D003598:Cytoskeletal Proteins; D015534:Trans-Activators; D051176:beta Catenin