Protection against Ehrlichia equi is conferred by prior infection with the human granulocytotropic Ehrlichia (HGE agent).
A Thoroughbred filly that developed clinical signs of equine granulocytic ehrlichiosis following inoculation with the human granulocytotropic ehrlichia was shown to be resistant to challenge with Ehrlichia equi, a closely related agent. This result further substantiates the close and potentially conspecific relationship between these two granulocytotropic ehrlichiae.
Barlough
J E
JE
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA.
Madigan
J E
JE
DeRock
E
E
Dumler
J S
JS
Bakken
J S
JS
D000818:Animals; D004269:DNA, Bacterial / Q000235:genetics; D004536:Ehrlichia / Q000235:genetics / Q000276:immunology* / Q000472:pathogenicity; D016873:Ehrlichiosis / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D006098:Granulocytes / Q000382:microbiology*; D006734:Horse Diseases / Q000276:immunology* / Q000382:microbiology / Q000517:prevention & control; D006736:Horses; D006801:Humans; D016133:Polymerase Chain Reaction; D013045:Species Specificity
D004269:DNA, Bacterial