[Anti-hemophilia drugs: from cryoprecipitate to factor VIII concentrates of high purity].
The methods have been surveyed concerning the isolation of concentrates of the factor VIII which are the drugs used in treatment of a hereditary disease--hemophilia. Prospects of improvement of these drugs have been considered, their characteristics (activity, purity, method of virus inactivation) are presented that permits one to orientate himself in a wide assortment of drugs, as well as to choose the concrete drug to be used in clinic.
Gutsalo
A E
AE
Varetskaia
T V
TV
Kozulina
E P
EP
Papaian
L P
LP
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D015925:Cryopreservation; D005169:Factor VIII / Q000302:isolation & purification / Q000627:therapeutic use*; D006467:Hemophilia A / Q000188:drug therapy*; D006358:Hot Temperature; D006801:Humans; D014841:von Willebrand Factor / Q000302:isolation & purification
D000998:Antiviral Agents; D014841:von Willebrand Factor; D005169:Factor VIII