Severe Raynaud's syndrome associated with interferon therapy. A case history.
Side effects of long-term interferon (IFN) therapy for myeloproliferative disorders may be vasospastic Raynaud's attacks and lupus-like illness. The authors report on a woman with chronic myelogenous leukemia who experienced severe trophic lesions of the fingers after forty-nine months of IFN therapy. Digital artery occlusions could be proven arteriographically.
Creutzig
A
A
Department of Angiology, Medizinische Hochschule, Hannover, Germany.
Freund
M
M
D000792:Angiography; D005260:Female; D005385:Fingers / Q000098:blood supply; D006801:Humans; D007372:Interferons / Q000009:adverse effects*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy; D008875:Middle Aged; D011928:Raynaud Disease / Q000209:etiology*
D007372:Interferons