Antigens from Taenia crassiceps cysticerci used in complement fixation, enzyme-linked immunosorbent assay, and western blot (immunoblot) for diagnosis of neurocysticercosis.
Antigens from Taenia solium cysticerci for the immunodiagnosis of cysticercosis are scarce and difficult to obtain. We studied the reliability of antigens from Taenia crassiceps cysticerci as a substitute for those from T. solium in three diagnostic tests: complement fixation, enzyme-linked immunosorbent assay, and Western blot (immunoblot). Precision rates of the three tests of 93, 99, and 96%, respectively, were found. Cysticerci from T. crassiceps can be easily obtained in large quantities and can be effectively used for the diagnosis of human neurocysticercosis.
Garcia
E
E
Research Division, National Institute of Neurology and Neurosurgery of Mexico, Mexico City, Mexico.
Ordoñez
G
G
Sotelo
J
J
D000818:Animals; D000909:Antibodies, Helminth / Q000134:cerebrospinal fluid; D000947:Antigens, Helminth; D015153:Blotting, Western / Q000379:methods; D001927:Brain Diseases / Q000175:diagnosis* / Q000276:immunology; D003168:Complement Fixation Tests / Q000379:methods; D003551:Cysticercosis / Q000175:diagnosis* / Q000276:immunology; D003552:Cysticercus / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005069:Evaluation Studies as Topic; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*
D000909:Antibodies, Helminth; D000947:Antigens, Helminth