[Observation on the animal model of hypoxic-ischemic encephalopathy and the change of pathology in newborn pigs].
Thirty newborn pigs within 3 days of life were randomly divided into different groups according to the time of hypoxic-ischemic encephalopathy. The results showed that the brain damage and pathologic changes were most obvious in the 60 min hypoxia-ischemic group. Brain edema was observed in every group, especially in the group where hypoxia-ischemic lasted for more than 30 min. Cerebromalacia and hemorrhage in ventricles of brain and in arachnoid were observed, and these were particularly noticed in the group where hypoxia-ischemia lasted for 60 min.
Li
W
W
Yao
Y
Y
Tan
J
J
D000818:Animals; D000831:Animals, Newborn; D001929:Brain Edema / Q000209:etiology / Q000473:pathology*; D002545:Brain Ischemia / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000473:pathology; D004195:Disease Models, Animal; D002534:Hypoxia, Brain / Q000473:pathology*; D011897:Random Allocation; D013552:Swine