title: CLECOS_P: clinical evolution control system on Parkinsonian patients undergoing neural transplantation.
abstract: The CLECOS_P system was conceived for registering and automating the processing of clinical evaluations performed on patients with Parkinson's disease who undergo functional neurosurgery and/or neural transplant. CLECOS_P represents the first time a computerized system is able to offer--with high precision and considerable time-savings--an integral analysis of the evolutive behavior of the universe in integrated variables at the core assessment program for intracerebral transplantations (CAPIT). CAPIT is used internationally for the evaluation and follow-up of patients with this pathology who have undergone neural transplant. We used the so-called MEDSAC methodology for the preparation of this system. The methodology that was used for the design of an intelligent system aimed at medical decision-making was based on the quantitative analysis of the clinical evolution. At the present moment, there are 20 patients controlled by this system: 11 bilaterally transplanted, 9 unilaterally (registered in ranks of 3 months before operation up to 1, 2, 3, 6, 9, 12, 18, and 24 months after operation). The application of CLECOS_P to these patients permitted the evaluation of 400 clinical variables, where a better evolutive characterization of the patients was obtained, thus getting most favorable results with personalized therapeutic methods aimed at raising their quality of life. CLECOS_P is used in a multi-user environment on a local area network running Novell Netware version 3.11.
authors.affiliation: International Center for Neurological Restoration, Ave. 25 #15805, Cubanacan, Playa, C. de La Habana, CP 12100, Cuba.
authors.forename: F
authors.initials: F
authors.lastname: Morales
authors.forename: H
authors.initials: H
authors.lastname: Molina
authors.forename: N
authors.initials: N
authors.lastname: Cruz
authors.forename: P
authors.initials: P
authors.lastname: Valladares
authors.forename: J
authors.initials: J
authors.lastname: Muñoz
authors.forename: I
authors.initials: I
authors.lastname: Ortega
authors.forename: O
authors.initials: O
authors.lastname: Torres
authors.forename: M
authors.initials: M
authors.lastname: Leon
mesh_terms: D016380:Brain Tissue Transplantation; D003199:Computer Systems; D003627:Data Interpretation, Statistical; D003658:Decision Making, Computer-Assisted; D005103:Expert Systems; D005500:Follow-Up Studies; D006801:Humans; D010300:Parkinson Disease / Q000175:diagnosis / Q000601:surgery*; D014584:User-Computer Interface