title: Diagnostic and genetic issues of depression and bipolar illness.
abstract: Depression and bipolar illness are the major affective disorders. Various genetic studies indicate the existence of inherited susceptibility factors. Recent linkage studies indicate that loci on chromosomes 18, 21, and X contribute to genetic susceptibility of bipolar illness.
authors.affiliation: Department of Psychiatry, Thomas Jefferson University, Philadelphia, PA 19107, USA.
authors.forename: W
authors.initials: W
authors.lastname: Berrettini
mesh_terms: D001714:Bipolar Disorder / Q000175:diagnosis / Q000235:genetics*; D002887:Chromosomes, Human, Pair 18 / Q000235:genetics; D002891:Chromosomes, Human, Pair 21 / Q000235:genetics; D003863:Depression / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D014960:X Chromosome / Q000235:genetics