Severe hemolytic disease of the newborn due to anti-Js(b).
Anti-Js(b) has not been reported to cause severe hemolytic disease of the newborn requiring intrauterine evaluation and treatment. We now report on such a patient with high-titered anti-Js(b) causing fetal hydrops with demise in one pregnancy, followed by a pregnancy treated with multiple intrauterine fetal transfusions.
Gordon
M C
MC
Department of Obstetrics & Gynecology, Ohio State University Medical Center, Columbus 43210, USA.
Kennedy
M S
MS
O'Shaughnessy
R W
RW
Waheed
A
A
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D001803:Blood Transfusion; D001805:Blood Transfusion, Intrauterine; D004899:Erythroblastosis, Fetal / Q000276:immunology* / Q000628:therapy; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D005313:Fetal Death / Q000276:immunology; D005315:Fetal Diseases / Q000276:immunology* / Q000628:therapy; D006801:Humans; D015160:Hydrops Fetalis / Q000276:immunology; D007231:Infant, Newborn; D007518:Isoantibodies / Q000276:immunology*; D007626:Kell Blood-Group System / Q000276:immunology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*
D007518:Isoantibodies; D007626:Kell Blood-Group System