title: Vegetable oil as an MR contrast agent for rectal applications.
abstract: The purpose of this study was to evaluate the feasibility of pure vegetable oil as an MR contrast agent for rectal applications. The hypothesis was that vegetable oil highlights the lumen of the rectum after rectal application as a positive contrast medium and offers additional contrast qualities using fat suppression techniques. Eleven MRI examinations were performed on 11 subjects (five healthy volunteers, all males, mean age 35 yr; and six patients, three males, three females, mean age 49 yr). Peanut oil, 200 ml, was applied rectally. In addition, 0.1 mmol/kg GD-DTPA was administered intravenously to the six patients only. Conventional T1-weighted SE sequences and T1-weighted SE images with fat suppression were obtained. Criteria for image evaluation were: overall image quality; uniformity of contrast distribution; chemical shift artifact; and delineation of the rectal wall. Side effects were assessed. There were no complaints reported by the 11 subjects. The image quality was sufficient in all studies. In all five of the volunteers and five of the six patients, the distribution of oil was uniform. Chemical shift artifacts did not deteriorate image quality. After rectal application of vegetable oil, the delineation of the rectal wall was sufficient with and without fat suppression techniques. Vegetable oil highlights the lumen of the rectum in MRI studies and offers additional contrast qualities with fat suppression techniques, acting as a positive as well as a negative contrast agent, depending on the chosen sequence.
authors.affiliation: Department of Radiology, University of Vienna, Austria.
authors.forename: P
authors.initials: P
authors.lastname: Pokieser
authors.forename: E
authors.initials: E
authors.lastname: Schober
authors.forename: K
authors.initials: K
authors.lastname: Hittmair
authors.forename: J
authors.initials: J
authors.lastname: Kettenbach
authors.forename: J
authors.initials: J
authors.lastname: Naudé
authors.forename: F
authors.initials: F
authors.lastname: Herbst
authors.forename: J
authors.initials: J
authors.lastname: Karner-Hanusch
authors.forename: R
authors.initials: R
authors.lastname: Segel
authors.forename: H
authors.initials: H
authors.lastname: Imhof
authors.forename: J
authors.initials: J
authors.lastname: Kramer
mesh_terms: D000285:Administration, Rectal; D000328:Adult; D010367:Arachis; D016022:Case-Control Studies; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D000074241:Peanut Oil; D004369:Pentetic Acid / Q000031:analogs & derivatives; D010938:Plant Oils; D012004:Rectal Neoplasms / Q000175:diagnosis*; D012007:Rectum / Q000033:anatomy & histology* / Q000473:pathology
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D000074241:Peanut Oil; D010938:Plant Oils; D004369:Pentetic Acid; D019786:Gadolinium DTPA