title: Evaluation of the safety of sodium pectate as a food ingredient.
abstract: New potential uses of pectates in food products have recently stimulated interest in re-evaluating the information available concerning the safety of pectins and pectates as food ingredients. Data relevant to this re-evaluation have been obtained in rats in recent 14-day and 13 wk subchronic feeding studies with sodium pectate. Ames tests and other mutagenicity tests have been conducted with sodium pectate, bleached sodium pectate and mixed sodium/calcium pectate salts. These toxicological studies with pectates have provided further evidence of their safety, and support of the continued GRAS status of pectins and pectate salts.
authors.affiliation: Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond, USA.
authors.forename: J F
authors.initials: JF
authors.lastname: Borzelleca
authors.forename: L J
authors.initials: LJ
authors.lastname: Filer
authors.forename: F K
authors.initials: FK
authors.lastname: Kinoshita
authors.forename: T C
authors.initials: TC
authors.lastname: Gerrish
authors.forename: P K
authors.initials: PK
authors.lastname: Kuo
authors.forename: B N
authors.initials: BN
authors.lastname: La Du
mesh_terms: D000818:Animals; D003257:Consumer Product Safety; D005503:Food Additives / Q000008:administration & dosage / Q000633:toxicity; D006801:Humans; D009152:Mutagenicity Tests; D010368:Pectins / Q000008:administration & dosage / Q000633:toxicity
chemical_list: D005503:Food Additives; D010368:Pectins; C003181:polygalacturonic acid