title: Genetic pre-disposition to colorectal cancer: Initiation of a prospective study in Eastern Ontario.
abstract: A pilot study which is part of both a larger provincial initiative and a network is in progress to address the question of genetic pre-disposition to non-polyposis colorectal cancer in eastern Ontario (population 1,200,000). It is modeled along a dual process of recruitment of at-risk individuals based on either prior documentation of family histories or a close relationship to patients who are hospitalized for colorectal cancer treatment. The molecular diagnostic and genetic counseling components of the project are in their initial phase of operation while follow-up strategies are being planned.
authors.affiliation: Loeb Medical Research Institute, Ottawa Civic Hospital, Canada.
authors.forename: A E
authors.initials: AE
authors.lastname: Lagarde
authors.forename: H S
authors.initials: HS
authors.lastname: Stern
mesh_terms: D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D004198:Disease Susceptibility; D005192:Family Health; D006801:Humans; D009864:Ontario / Q000453:epidemiology; D010865:Pilot Projects; D011446:Prospective Studies; D012307:Risk Factors