title: Production of corticotropin-releasing hormone-deficient mice by targeted mutation in embryonic stem cells.
authors.affiliation: Division of Endocrinology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors.forename: L
authors.initials: L
authors.lastname: Muglia
authors.forename: L
authors.initials: L
authors.lastname: Jacobson
authors.forename: J A
authors.initials: JA
authors.lastname: Majzoub
mesh_terms: D000818:Animals; D003346:Corticotropin-Releasing Hormone / Q000096:biosynthesis / Q000172:deficiency* / Q000235:genetics*; D003433:Crosses, Genetic; D004622:Embryo, Mammalian; D005260:Female; D015870:Gene Expression; D006720:Homozygote; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D016296:Mutagenesis; D010913:Pituitary-Adrenal System / Q000502:physiology*; D012727:Sex Characteristics; D013234:Stem Cells; D013315:Stress, Psychological / Q000235:genetics / Q000503:physiopathology
chemical_list: D003346:Corticotropin-Releasing Hormone