title: The transverse location of the fluorescent probe trans-parinaric acid in lipid bilayers.
abstract: The transverse location of trans-parinaric acid in spherical vesicles made up from dipalmitoylphosphatidylcholine has been investigated by the differential quenching of the probe fluorescence by 5- and 16-doxylstearic acid derivatives. The quenching data are interpreted in terms of a local fluorophore concentration factor. In this way it was found that the polyene of t-PnA is located within the inner part of the bilayer (presumably aligned with the bilayer lipids), both in the gel and in the liquid crystalline phases.
authors.affiliation: Centro de Química-Física Molecular, Instituto Superior Técnico, Lisboa, Portugal.
authors.forename: M
authors.initials: M
authors.lastname: Castanho
authors.forename: M
authors.initials: M
authors.lastname: Prieto
authors.forename: A U
authors.initials: AU
authors.lastname: Acuña
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine / Q000737:chemistry*; D003497:Cyclic N-Oxides; D005231:Fatty Acids, Unsaturated / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D013113:Spin Labels
chemical_list: D003497:Cyclic N-Oxides; D005231:Fatty Acids, Unsaturated; D005456:Fluorescent Dyes; D008051:Lipid Bilayers; D013113:Spin Labels; D015060:1,2-Dipalmitoylphosphatidylcholine; C005072:5-doxylstearic acid; C032363:16-nitroxystearic acid; C013641:parinaric acid