Primary amino-terminal heterobifunctional poly(ethylene oxide). Facile synthesis of poly(ethylene oxide) with a primary amino group at one end and a hydroxyl group at the other end.
Well-defined poly(ethylene oxide) (PEO) with a cyano group at one end and a hydroxyl group at the other terminus was synthesized by the anionic ring opening polymerization of ethylene oxide (EO) initiated with (cyanomethyl)potassium (CMP) which was prepared by the metalation reaction of acetonitrile with potassium naphthalene in THF. Primary amino-terminal heterotelechelic PEO was obtained by the reduction of the cyano group at the end of the polymer chain by lithium aluminum hydride.
Nagasaki
Y
Y
Department of Materials Science and Technology, Science University of Tokyo, Japan.
Iijima
M
M
Kato
M
M
Kataoka
K
K
D000097:Acetonitriles / Q000737:chemistry; D017607:Aluminum Compounds / Q000737:chemistry; D003432:Cross-Linking Reagents; D018020:Lithium Compounds / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry; D010084:Oxidation-Reduction; D011092:Polyethylene Glycols / Q000138:chemical synthesis* / Q000737:chemistry
D000097:Acetonitriles; D017607:Aluminum Compounds; D003432:Cross-Linking Reagents; D018020:Lithium Compounds; D009281:Naphthalenes; C099033:acetonitrile anion; C031721:naphthalene; D011092:Polyethylene Glycols; C042073:lithium aluminum hydride; C032159:acetonitrile