State of the science. HIV vaccine development.
Developing a vaccine able to prevent HIV infection would be a great benefit to the world. Vaccines have contributed to substantially reduced morbidity and mortality from several important infectious diseases. However, HIV has some characteristics that distinguish it from many other viruses and make vaccine development challenging. This article discusses scientific strategies, obstacles, and progress to date towards the development of a preventive HIV vaccine.
Grady
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National Institute of Nursing Research, National Institutes of Health, Bethesda, Maryland, USA.
Kelly
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D016915:AIDS Vaccines / Q000276:immunology / Q000627:therapeutic use*; D004341:Drug Evaluation; D015658:HIV Infections / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D014613:Vaccines, Attenuated / Q000627:therapeutic use; D015164:Vaccines, Inactivated / Q000627:therapeutic use
D016915:AIDS Vaccines; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated