title: Protein sorting by transport vesicles.
abstract: Eukaryotic life depends on the spatial and temporal organization of cellular membrane systems. Recent advances in understanding the machinery of vesicle transport have established general principles that underlie a broad variety of physiological processes, including cell surface growth, the biogenesis of distinct intracellular organelles, endocytosis, and the controlled release of hormones and neurotransmitters.
authors.affiliation: Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, 10021, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Rothman
authors.forename: F T
authors.initials: FT
authors.lastname: Wieland
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001692:Biological Transport; D002451:Cell Compartmentation; D002462:Cell Membrane / Q000378:metabolism*; D018699:Coated Vesicles / Q000378:metabolism; D004705:Endocytosis; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006056:Golgi Apparatus / Q000378:metabolism; D006728:Hormones / Q000378:metabolism; D007425:Intracellular Membranes / Q000378:metabolism*; D008561:Membrane Fusion; D008565:Membrane Proteins / Q000378:metabolism; D008969:Molecular Sequence Data; D018377:Neurotransmitter Agents / Q000378:metabolism; D015388:Organelles / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*
chemical_list: D006728:Hormones; D008565:Membrane Proteins; D018377:Neurotransmitter Agents; D011506:Proteins