title: Choroidal hemorrhage associated with systemic tissue plasminogen activator.
abstract: OBJECTIVE
  To determine the cause of spontaneous choroidal hemorrhage in a 67-year-old man after a myocardial infarction and administration of tissue plasminogen activator.
  
  
  METHODS
  The patient underwent ocular examination.
  
  
  RESULTS
  The patient retained excellent visual acuity and the choroidal hemorrhage resolved completely within two months.
  
  
  CONCLUSIONS
  The administration of tissue plasminogen activator was responsible for the large extent of hemorrhage and should be considered in the differential diagnosis of hemorrhagic choroidal detachment.
authors.affiliation: Department of Ophthalmology, Duke University Eye Center, NC 27710, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Khawly
authors.forename: P J
authors.initials: PJ
authors.lastname: Ferrone
authors.forename: D E
authors.initials: DE
authors.lastname: Holck
mesh_terms: D000368:Aged; D002829:Choroid / Q000000981:diagnostic imaging; D015862:Choroid Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging; D002832:Choroid Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy; D010960:Plasminogen Activators / Q000009:adverse effects* / Q000627:therapeutic use; D010959:Tissue Plasminogen Activator / Q000009:adverse effects* / Q000627:therapeutic use; D014463:Ultrasonography; D014792:Visual Acuity
chemical_list: D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator