title: [Management of premature rupture of fetal membranes in obstetrical departments in Germany].
abstract: Since the treatment of premature ruptures of membranes is not only controversial in the German but also in the international literature, we performed a survey of all obstetrics departments in Germany. From a total of 843 hospitals, 444 questionnaires were returned for evaluation (52.7%). The purpose was to determine which diagnostic and therapeutic regimes are used and how these agree with the literature. In addition to questions on the type of hospital, birth rates with a percentage of premature births and applied diagnostic parameters, our special interest focused on therapy, particularly with regard to prophylactic antibiotic application, tocolytic treatment and lung maturity induction. Prophylactic antibiotics are used in 36.7% and prophylactic tocolytic therapy in 41.7% of the departments. Interestingly, lung maturity induction was performed in 93.5%, in part even before the 28th week of pregnancy, although the effect of this therapy has not yet been proven at a very early stage of gestation. Due to the different views in the literature and, in part, a lack of basic scientific data, it seems there is a preference for the procedure, in which the best personal experience has been made. Because premature ruptures of the membranes is responsible for 30-40% of premature births, it is urgently necessary to clarify this controversial problem by large multicenter studies so that the treatment of early premature ruptures of the amnion can be founded on a rational basis.
authors.affiliation: Universitätsfrauenklinik im Klinikum Benjamin Franklin, Berlin.
authors.forename: V
authors.initials: V
authors.lastname: Ragosch
authors.forename: S
authors.initials: S
authors.lastname: Hundertmark
authors.forename: N
authors.initials: N
authors.lastname: Fuhr
authors.forename: H
authors.initials: H
authors.lastname: Hopp
authors.forename: H
authors.initials: H
authors.lastname: Weitzel
mesh_terms: D019072:Antibiotic Prophylaxis; D003430:Cross-Sectional Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000453:epidemiology / Q000517:prevention & control / Q000628:therapy; D011247:Pregnancy; D011295:Prenatal Care; D012127:Respiratory Distress Syndrome, Newborn / Q000453:epidemiology / Q000517:prevention & control; D012307:Risk Factors; D015145:Tocolysis