Infection and male infertility: effect of different antibiotic regimens on semen quality.
Objective criteria of semen quality were evaluated in 60 men with positive culture of semen after treatment with two different antibiotics and compared with placebo. Group I received 160 mg trimethoprim and 800 mg sulfamethoxazole twice a day, group II received 250 mg ciprofloxacin twice a day, and group III received a placebo. No difference was recorded between antibiotic treatment and placebo in sperm quality but accessory gland function was modified.
Merino
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G
Servicio de Ginecología Endocrina/Andrología, Hospital de Gineco-Obstetricia, Mexico DF, Mexico.
Carranza-Lira
S
S
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use; D000892:Anti-Infective Agents, Urinary / Q000494:pharmacology / Q000627:therapeutic use; D001424:Bacterial Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology; D002939:Ciprofloxacin / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007248:Infertility, Male / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D012661:Semen / Q000187:drug effects* / Q000382:microbiology / Q000502:physiology*; D013420:Sulfamethoxazole / Q000494:pharmacology / Q000627:therapeutic use; D000077145:Sulfanilamide; D013424:Sulfanilamides / Q000494:pharmacology / Q000627:therapeutic use; D014295:Trimethoprim / Q000494:pharmacology / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000892:Anti-Infective Agents, Urinary; D013424:Sulfanilamides; D000077145:Sulfanilamide; D002939:Ciprofloxacin; D014295:Trimethoprim; D013420:Sulfamethoxazole