Activity of sucralfate (sucrose octa-sulphate), an anti-ulcer agent, against opportunistic gram-negative bacilli.
The in-vitro activity of sucralfate (sucrose octa-sulphate) in suspension was examined against 128 strains of Gram-negative bacilli. Inhibitory activity was demonstrated against all isolates and bactericidal activity was demonstrated for 68. Sucralfate has inhibitory and bactericidal antibacterial activity which may contribute to its in-vivo clinical efficacy.
Bragman
S G
SG
Dulwich Public Health Laboratory, King's College School of Medicine and Dentistry, London, UK.
Pankhurst
C L
CL
Casewell
M W
MW
D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009894:Opportunistic Infections / Q000382:microbiology*; D013392:Sucralfate / Q000494:pharmacology*
D000897:Anti-Ulcer Agents; D013392:Sucralfate