title: Clinical study to assess the stain removal efficacy of two tartar control dentifrices and a low abrasive dentifrice.
abstract: Significant differences in stain removal have been demonstrated in a laboratory study comparing two tartar control dentifrices: Platinum, containing 1.3% soluble pyrophosphate and 1.5% of a copolymer, and Crest Tartar Control, containing 5% soluble pyrophosphate. The purpose of this clinical study was to evaluate the same tartar control dentifrices, and a low abrasive dentifrice for their ability to reduce Peridex-induced stain. Eighty-five subjects were given Peridex (0.12% chlorhexidine digluconate) and a low abrasive dentifrice for 4 weeks. The 76 subjects with sufficient stain were stratified using the Lobene index on buccal and lingual surfaces of anterior teeth, and randomly assigned one of the three dentifrices for 8 weeks. At the end of the study, total stain evaluations were significantly lower in the Platinum dentifrice group (mean 0.84) compared to both Crest Tartar Control dentifrice (1.08) and the low abrasive dentifrice (1.09) at p<0.05 by ANOVA. In this 8-week clinical study, Platinum dentifrice was significantly more effective than Crest Tartar Control dentifrice or a low abrasive dentifrice in reducing Peridex-induced stain, and this finding correlates well with laboratory data on removal of tea and coffee stain.
authors.affiliation: University of Pennsylvania School of Dental Medicine, Philadelphia, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Yankell
authors.forename: R C
authors.initials: RC
authors.lastname: Emling
authors.forename: M
authors.initials: M
authors.lastname: Prencipe
authors.forename: K
authors.initials: K
authors.lastname: Rustogi
authors.forename: A R
authors.initials: AR
authors.lastname: Volpe
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002710:Chlorhexidine / Q000009:adverse effects / Q000031:analogs & derivatives; D003802:Dentifrices / Q000627:therapeutic use*; D011756:Diphosphates / Q000627:therapeutic use; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011095:Polyethylenes / Q000627:therapeutic use; D012969:Sodium Fluoride / Q000627:therapeutic use; D014075:Tooth Discoloration / Q000139:chemically induced / Q000628:therapy*
chemical_list: C098422:Crest Tartar Control; D003802:Dentifrices; D011756:Diphosphates; D004338:Drug Combinations; C098979:Platinum Dentifrice; D011095:Polyethylenes; D012969:Sodium Fluoride; C010882:chlorhexidine gluconate; D002710:Chlorhexidine