[Cushing's syndrome associated with a metastatic medullary carcinoma of the thyroid. A report of 2 cases and a review of the literature].
An ectopic Cushing syndrome (CS) caused by a medullary thyroid carcinoma (MTC) is an exceptional observation. Two patients are here reported with metastatic MTC, who developed CS two years after the thyroid cancer was diagnosed. A review is also made of clinical and biochemical characteristics of cases with MTC associated with ectopic CS reported in the literature and it is concluded that the cortico-adrenal function in follow-up should be monitored in patients with this type of cancer.
Martínez Díaz-Guerra
G
G
Servicio de Endocrinología y Nutrición, Hospital Universitario 12 de Octubre, Madrid.
Rigopoulou
D
D
Gómez
I
I
Fernández-Salas
M C
MC
León
M
M
Hawkins
F
F
D000368:Aged; D018276:Carcinoma, Medullary / Q000150:complications / Q000175:diagnosis* / Q000556:secondary*; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008479:Mediastinal Neoplasms / Q000556:secondary; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000150:complications / Q000175:diagnosis*