[Interferon-associated retinopathy].
BACKGROUND
Recently interferons have been utilized for hepatitis C or some other tumorous conditions. However, a new interferon-associated retinopathy has been reported. There are to our knowledge, no publications in German-speaking countries.


METHODS
Four patients developed after interferon therapy cotton-wool spots combined with splinter hemorrhage.


RESULTS
The retinopathy occurred 5-30 days after the beginning of the therapy. In one case the retinopathy aggravated following dose elevation, whereas in two other cases the cotton-wool spots and hemorrhages disappeared irrespective of continued interferon therapy.


CONCLUSIONS
Interferons cannot be primarily responsible for the development of retinopathy.
Hararda
T
T
Augenklinik Fujita Health University Toyoake.
Fukami
H
H
Takeuchi
T
T
Niwa
T
T
Majima
Y
Y
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000628:therapy; D005260:Female; D005451:Fluorescein Angiography; D006526:Hepatitis C / Q000628:therapy; D006801:Humans; D007372:Interferons / Q000009:adverse effects* / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012166:Retinal Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis; D012307:Risk Factors
D007372:Interferons