title: Selenium in serum and whole blood in patients with surgical interventions.
abstract: Selenium values of serum and whole blood were determined for two groups of patients undergoing large surgical interventions (e.g., gastrectomy) and receiving a total parenteral nutrition (TPN). All patients showed low selenium values at the beginning of TPN. The first group received a supplementation of selenium, and it was established that selenium levels normalized after 6-7 d. The balances of selenium turned out to be positive in all cases. The second group, which was not administered selenium supplementation, showed significantly lower values of selenium. It can, therefore, be concluded that a substitution of selenium prior to large surgical interventions following TPN clearly helps patients combat the increase in the oxidant stress reactions.
authors.affiliation: Surgical Clinic, Friedrich Schiller University, Jena, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Winnefeld
authors.forename: H
authors.initials: H
authors.lastname: Dawczynski
authors.forename: W
authors.initials: W
authors.lastname: Schirrmeister
authors.forename: G
authors.initials: G
authors.lastname: Adam
authors.forename: U
authors.initials: U
authors.lastname: Friedrich
authors.forename: S
authors.initials: S
authors.lastname: Hein
mesh_terms: D000368:Aged; D005743:Gastrectomy; D006801:Humans; D008875:Middle Aged; D010289:Parenteral Nutrition, Total; D017382:Reactive Oxygen Species; D012643:Selenium / Q000097:blood*
chemical_list: D017382:Reactive Oxygen Species; D012643:Selenium