Visual function after laser hyperthermia and chemotherapy for macular retinoblastoma.
OBJECTIVE
To determine whether treatment of macular retinoblastoma with chemotherapy and laser hyperthermia can lead to satisfactory visual acuity.


METHODS
A child with unilateral macular retinoblastoma was treated with chemotherapy and laser hyperthermia. Visual function was assessed one year after treatment.


RESULTS
At age 25 months, the patient had normal visual behavior and a normal spatial-sweep visual-evoked potential.


CONCLUSIONS
Treatment of macular retinoblastoma with chemotherapy and laser hyperthermia may enable recovery of satisfactory visual acuity.
Lueder
G T
GT
Departments of Ophthalmology and Visual Sciences, Washington University Medical Center and St. Louis Children's Hospital, MO 63110, USA.
Goyal
R
R
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005047:Etoposide / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D007223:Infant; D007834:Lasers; D008266:Macula Lutea / Q000473:pathology / Q000503:physiopathology*; D012175:Retinoblastoma / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D014750:Vincristine / Q000627:therapeutic use; D014792:Visual Acuity / Q000502:physiology*
D014750:Vincristine; D005047:Etoposide; D016190:Carboplatin