High-grade astrocytomas.
Despite intense research, progress in the treatment of patients with HGA has remained slow. New therapeutic strategies are emerging, however, based on technologic advances in surgery and radiotherapy, improved understanding of the molecular, cellular, and immunobiology of astrocytomas, and advances in gene therapy, It is likely that these new strategies will result in significant progress in the treatment of HGA in the next decade.
Wen
P Y
PY
Brain Tumor Center of Brigham and Women's Hospital, Boston, Massachusetts, USA.
Fine
H A
HA
Black
P M
PM
Shrieve
D C
DC
Alexander
E
E
Loeffler
J S
JS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001254:Astrocytoma / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D005500:Follow-Up Studies; D005909:Glioblastoma / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D015996:Survival Rate