Canine cognitive dysfunction as a model for human age-related cognitive decline, dementia and Alzheimer's disease: clinical presentation, cognitive testing, pathology and response to 1-deprenyl therapy.
Ruehl
W W
WW
Deprenyl Animal Health, Inc., Overland Park, KS 66210, USA.
Bruyette
D S
DS
DePaoli
A
A
Cotman
C W
CW
Head
E
E
Milgram
N W
NW
Cummings
B J
BJ
D000375:Aging / Q000502:physiology; D000544:Alzheimer Disease / Q000188:drug therapy / Q000503:physiopathology*; D000818:Animals; D003072:Cognition Disorders / Q000188:drug therapy / Q000503:physiopathology*; D003704:Dementia / Q000188:drug therapy / Q000503:physiopathology; D004195:Disease Models, Animal; D004285:Dogs; D006801:Humans; D012642:Selegiline / Q000627:therapeutic use*
D012642:Selegiline