The pathologies of bovine viral diarrhea virus infection. A window on the pathogenesis.
Pathologic lesions caused by bovine viral diarrhea virus (BVDV) infections comprise a wide spectrum of type, degree, and, by implication, pathogenesis, including congenital defects, necroticerosive lesions in mucosal epithelia and skin, and reactive as well as degenerative changes in lymphoid tissues. At least some of the pathology may not be solely due to BVDV replication per se, but rather caused by a host response to the virus, particularly the production of pro-inflammatory cytokines.
Bielefeldt-Ohmann
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Centre for Molecular Biotechnology (Arbovirology Group) School of Life Science, Queensland University of Technology, Brisbane, Australia.
D000208:Acute Disease; D000818:Animals; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000151:congenital / Q000209:etiology* / Q000473:pathology*; D002417:Cattle; D002418:Cattle Diseases / Q000151:congenital / Q000473:pathology / Q000821:virology; D016207:Cytokines / Q000502:physiology; D001908:Diarrhea Viruses, Bovine Viral / Q000502:physiology; D008171:Lung Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary; D013921:Thrombocytopenia / Q000209:etiology / Q000473:pathology / Q000662:veterinary
D016207:Cytokines