title: Rotavirus pathogenicity.
abstract: The pathogenicity of rotaviruses depends on multiple viral and host factors. In this review the evidence for the involvement of a number of viral genes in the ability to cause disease is presented. Different genes are of importance in different rotavirus-host systems: there is no single pathogenicity factor.
authors.affiliation: Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, United Kingdom.
authors.forename: B
authors.initials: B
authors.lastname: Burke
authors.forename: U
authors.initials: U
authors.lastname: Desselberger
mesh_terms: D000818:Animals; D005814:Genes, Viral / Q000502:physiology; D006801:Humans; D012401:Rotavirus / Q000472:pathogenicity*; D012400:Rotavirus Infections / Q000821:virology