title: The effect of aspirin on the visual outcome of nonarteritic anterior ischemic optic neuropathy.
abstract: OBJECTIVE
  To examine the effect of aspirin use on the visual outcome of nonarteritic anterior ischemic optic neuropathy.
  
  
  METHODS
  This retrospective case-controlled study included 23 patients who used aspirin regularly before and during the course of nonarteritic anterior ischemic optic neuropathy and 55 control patients with nonarteritic anterior ischemic optic neuropathy. Snellen visual acuity in logMAR and mean deviation on automated perimetry were compiled from the initial and final follow-up examinations.
  
  
  RESULTS
  The comparisons of patients who took aspirin with control patients disclosed that neither initial logMAR (P = .36) nor the follow-up logMAR (P = .95) data differed significantly. There was no significant difference between the groups for the initial (P = .60) and the follow-up mean deviation (P = .41).
  
  
  CONCLUSIONS
  Aspirin use does not improve the visual outcome of patients with nonarteritic anterior ischemic optic neuropathy. Additional studies are needed to further elucidate this issue.
authors.affiliation: Mason Institute of Ophthalmology, University of Missouri-Columbia, Missouri 65212, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Botelho
authors.forename: L N
authors.initials: LN
authors.lastname: Johnson
authors.forename: A C
authors.initials: AC
authors.lastname: Arnold
mesh_terms: D000368:Aged; D001241:Aspirin / Q000494:pharmacology / Q000627:therapeutic use*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000188:drug therapy* / Q000503:physiopathology; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects* / Q000502:physiology
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin