title: Efficacy of three cavity liners in eliminating bacteria from infected dentinal tubules.
abstract: Three lining materials, Life, Ketac-Bond, and IRM, were investigated for their antibacterial effects within dentinal tubules. Sterile saline served as control. Sixty standardized bovine root specimens were infected with Enterococcus faecalis following smear layer removal. The materials were mixed according to manufacturer's directions and inserted in the canal lumina; additional IRM specimens received a softer than normal mix. Specimens were incubated for 24 hours or 7 days, after which dentinal samples were taken from within the lumina and the numbers of bacteria present were assessed. All the materials had a significant antibacterial effect after 7 days. Life demonstrated a more marked effect at 7 days than at 24 hours. The strongest antibacterial effect at 24 hours was shown by a "soft" mix of IRM. Ketac-Bond demonstrated an increase in antibacterial activity during the experimental period.
authors.affiliation: Department of Restorative Dentistry, University of Otago, School of Dentistry, Dunedin, New Zealand.
authors.forename: N P
authors.initials: NP
authors.lastname: Chandler
authors.forename: I
authors.initials: I
authors.lastname: Heling
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002126:Calcium Hydroxide / Q000494:pharmacology; D002417:Cattle; D003736:Dental Cavity Lining; D003764:Dental Materials / Q000494:pharmacology; D003804:Dentin / Q000382:microbiology*; D004203:Disinfection / Q000379:methods; D013293:Enterococcus faecalis / Q000187:drug effects; D005899:Glass Ionomer Cements / Q000494:pharmacology; D008768:Methylmethacrylates / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013997:Time Factors; D015035:Zinc Oxide-Eugenol Cement / Q000494:pharmacology
chemical_list: D000891:Anti-Infective Agents, Local; D003764:Dental Materials; D005899:Glass Ionomer Cements; D008768:Methylmethacrylates; D015035:Zinc Oxide-Eugenol Cement; C061499:Ketac-Bond; C031667:IRM cement; C040408:Life (dental material); D002126:Calcium Hydroxide