Transurethral collagen injections in the therapy of post-radical prostatectomy stress incontinence.
OBJECTIVE
We report on our initial results with glutaraldehyde cross-linked collagen used as an injectable bulking agent for the therapy of post-radical prostatectomy stress incontinence.


METHODS
A total of 19 men underwent collagen injection for treatment of post-radical prostatectomy stress incontinence.


RESULTS
Of the 19 patients treated 11 had either a good (4) or improved (7) result, for an overall satisfaction rate of 58% with a followup of 3 to 15 months (mean 10.4). Failure correlated with presence of bladder neck contracture or scarring and severity of incontinence.


CONCLUSIONS
Injection of collagen for stress incontinence after radical prostatectomy has an acceptable short-term success rate, particularly in men with milder incontinence and lack of bladder neck scarring.
Cummings
J M
JM
Division off Urology, St. Louis University School of Medicine, Missouri, USA.
Boullier
J A
JA
Parra
R O
RO
D003094:Collagen / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections / Q000379:methods; D008297:Male; D011468:Prostatectomy / Q000009:adverse effects; D019736:Prostheses and Implants; D012720:Severity of Illness Index; D014521:Urethra; D014550:Urinary Incontinence, Stress / Q000209:etiology / Q000628:therapy*
C048470:glutaraldehyde-cross-linked collagen; D003094:Collagen