title: Isolation of endothelin A receptor from bovine lungs.
abstract: We isolated endothelin receptor A (ETA) from bovine lungs in a single-step purification procedure using antibodies raised against synthetic peptides that correspond to extra- and intracellular domains of the rat bradykinin receptor. Two receptor species of 55 and 35 kDa were isolated and subjected to N-terminal microsequencing. The difference between the observed and expected molecular weight species suggests that bovine ETA receptor is glycosylated.
authors.affiliation: Institut für Physiologische Chemie und Pathobiochemie, Johannes Gutenberg Universität, Mainz, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Hick
authors.forename: J
authors.initials: J
authors.lastname: Godovac-Zimmermann
mesh_terms: D000818:Animals; D002417:Cattle; D008168:Lung / Q000737:chemistry*; D008970:Molecular Weight; D011817:Rabbits; D051381:Rats; D017466:Receptors, Endothelin / Q000302:isolation & purification*
chemical_list: D017466:Receptors, Endothelin