title: Treatment of nevus Ota: combined skin abrasion and carbon dioxide snow method.
abstract: Thirty-seven patients with nevus Ota were treated by skin abrasion-carbon dioxide snow therapy. Data obtained from 24 patients (including 5 infants) who completed treatment were analyzed to determine the number of treatment courses and to assess the outcome by color and histologic type. The 5 infants completing treatment received a mean of 10 courses of carbon dioxide snow therapy. Excluding these infants, the mean number of treatment courses was 3 for skin abrasion and 16 for carbon dioxide snow therapy. The therapeutic outcome was satisfactory, being graded as "excellent" in 6 patients, "excellent to good" in 6 patients, "good" in 10 Patients, and "fair" in 2 patients. None of the patients had a "poor" outcome. Darker lesions were generally less responsive to treatment. Lesions with melanocytes in the superficial dermis showed a better response with fewer courses of treatment. Those with melanocytes throughout the whole dermis generally had a poorer outcome. The results confirm that the benefits of this procedure are limited by the associated pain and the need for great skill and a long treatment duration.
authors.affiliation: Department of Plastic Surgery, Kagawa Medical School, Kagawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hata
authors.forename: K
authors.initials: K
authors.lastname: Matsuka
authors.forename: O
authors.initials: O
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Matsuda
authors.forename: H
authors.initials: H
authors.lastname: Furuichi
authors.forename: N
authors.initials: N
authors.lastname: Ishizu
authors.forename: A
authors.initials: A
authors.lastname: Konstantinos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003116:Color; D003131:Combined Modality Therapy; D017679:Cryotherapy / Q000379:methods*; D003869:Dermabrasion / Q000379:methods*; D004367:Dry Ice / Q000627:therapeutic use*; D005143:Eyelids / Q000601:surgery; D005145:Face / Q000473:pathology / Q000601:surgery; D005153:Facial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009507:Nevus of Ota / Q000473:pathology / Q000601:surgery*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016038:Skin Transplantation; D013997:Time Factors
chemical_list: D004367:Dry Ice