title: [Epidemiological characterization of a pestivirus isolate from a viremic pig out of a mixed pig-cattle herd].
abstract: A pestivirus isolated from a healthy pig out of a mixed pig-cattle holding was identified by use of monoclonal antibodies as a porcine virus related or identical to bovine viral diarrhoea (BVD) virus. About 7% of the pigs of this herd showed neutralizing antibodies (nab) against BVD and Border Disease (BD) virus and against the homologous porcine nonclassical swine fever (CSF) pestivirus isolate 10421/Han94. The nab titres against this virus were clearly higher than against CSF virus strain Alfort/187. Amongst the cattle kept in the farm no BVD viraemic animal was detected. About 13% of them showed nab to BVD virus with higher titres against the BVD virus strain NADL than against the porcine pestivirus virus isolate 10421/Han94. There was no of a BVD virus transmission from the cattle to the pigs within this herd. The problem of misinterpretation of non-CSF virus isolation from pigs is discussed. The necessity of identifying pestiviruses of porcine origin by use of species-specific monoclonal antibodies is stressed in order to prevent erroneous declarations of CSF outbreaks.
authors.affiliation: Institut für Virologie, Tierärztlichen Hochschule Hannover.
authors.forename: H R
authors.initials: HR
authors.lastname: Frey
authors.forename: B
authors.initials: B
authors.lastname: Röder
authors.forename: K
authors.initials: K
authors.lastname: Depner
authors.forename: B
authors.initials: B
authors.lastname: Liess
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral / Q000097:blood; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000635:transmission; D002417:Cattle; D003967:Diarrhea / Q000662:veterinary / Q000821:virology; D010576:Pestivirus / Q000302:isolation & purification*; D018182:Pestivirus Infections / Q000175:diagnosis / Q000662:veterinary*; D013552:Swine / Q000821:virology*; D013553:Swine Diseases; D014766:Viremia / Q000662:veterinary* / Q000821:virology
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral