A unique clonal chromosome 2 deletion in endomyometriosis.
The cytogenetic analysis of a short-term culture from a so-called endomyometriosis revealed a unique clonal del(2)(p21). The embryologic origin of this uterine-like mass is controversial. The finding of a clonal chromosome aberration favors the proliferation hypothesis and suggests that endomyometriosis is a true neoplasm and that a somatic mutation might be involved in the etiology of this lesion.
Verhest
A
A
Department of Cytogenetics, Institute Jules Bordet, Brussels, Belgium.
Simonart
T
T
Noël
J C
JC
D002871:Chromosome Banding; D002872:Chromosome Deletion; D002889:Chromosomes, Human, Pair 2; D016889:Endometrial Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007621:Karyotyping; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000473:pathology