Localisation of the gene encoding diacylglycerol kinase 3 (DAGK3) to human chromosome 3q27-28 and mouse chromosome 16.
The gene encoding a 90 kDa diacylglycerol kinase protein, DAGK3, that is predominately expressed in the retina, was localised by fluorescence in situ hybridisation to human chromosome 3q27-28. This was subsequently confirmed by mapping of its mouse homologue to chromosome 16, a region syntenic to this part of human chromosome 3. No retinopathies have so far been assigned to this region.
Fitzgibbon
J
J
Department of Molecular Genetics, University of London, UK.
Wells
D
D
Pilz
A
A
Delhanty
J
J
Kai
M
M
Kanoh
H
H
Hunt
D
D
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D004247:DNA / Q000032:analysis; D019852:Diacylglycerol Kinase; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL / Q000235:genetics*; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000032:analysis / Q000235:genetics*; D012160:Retina / Q000201:enzymology; D012689:Sequence Homology, Nucleic Acid
D004247:DNA; D017853:Phosphotransferases (Alcohol Group Acceptor); D019852:Diacylglycerol Kinase