title: Expression of c-fos protein in substance P receptor-like immunoreactive neurons in response to noxious stimuli on the urinary bladder: an observation in the lumbosacral cord segments of the rat.
abstract: Chemical irritation of the urinary bladder with formalin in the rat induced c-fos protein-like immunoreactivity in more than 80% of substance P receptor-like immunoreactive (SPR-LI) neurons of the dorsal commissural nucleus, sacral parasympathetic nucleus and lamina I in the 6th lumbar and 1st sacral cord segments. These neurons with SPR-LI may receive noxious information from the urinary bladder through the primary afferent fibers with substance P.
authors.affiliation: Department of Anatomy, Fourth Military Medical University, Xi'an, People's Republic of China.
authors.forename: Y
authors.initials: Y
authors.lastname: Lü
authors.forename: S X
authors.initials: SX
authors.lastname: Jin
authors.forename: T L
authors.initials: TL
authors.lastname: Xu
authors.forename: B Z
authors.initials: BZ
authors.lastname: Qin
authors.forename: J S
authors.initials: JS
authors.lastname: Li
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Ding
authors.forename: R
authors.initials: R
authors.lastname: Shigemoto
authors.forename: N
authors.initials: N
authors.lastname: Mizuno
mesh_terms: D000818:Animals; D005260:Female; D005557:Formaldehyde / Q000494:pharmacology; D007150:Immunohistochemistry; D066298:In Vitro Techniques; D007509:Irritants / Q000494:pharmacology; D009474:Neurons / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D018040:Receptors, Neurokinin-1 / Q000378:metabolism*; D013116:Spinal Cord / Q000166:cytology / Q000502:physiology*; D013268:Stimulation, Chemical; D001743:Urinary Bladder / Q000294:innervation* / Q000378:metabolism
chemical_list: D007509:Irritants; D016760:Proto-Oncogene Proteins c-fos; D018040:Receptors, Neurokinin-1; D005557:Formaldehyde