title: Effects of multibuffer supplementation on acid-base balance and 2,3-diphosphoglycerate following repetitive anaerobic exercise.
abstract: The purpose of this investigation was to determine the effects of a 3.5-day dietary multibuffer supplement (containing predominantly inorganic phosphate, or Pi, along with bicarbonate and carnosine, i.e., PhosFuel) on repetitive (four trials separated by 2 min rest) Wingate test (WT) performances and whole blood 2,3-diphosphoglycerate (2,3-DPG) concentrations in 10 recreationally trained road cyclists (T) and 10 normally active but untrained (UT) men. A 2-week washout period was utilized between experimental sessions. Venous blood samples were obtained via cannula once before exercise (baseline), immediately post each WT, and 3 min after the final WT (recovery). The data indicate that this supplement does not affect acid-base status with following intense anaerobic exercise and does not improve repetitive WT performance. However, the supplement does enhance post-exercise levels of 2,3-DPG and the 2,3-DPG/Hb ratio in recreationally trained cyclists while improving acute recovery of peak power in these men.
authors.affiliation: Center for Sports Medicine, Pennsylvania State University, University Park 16802, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Kraemer
authors.forename: S E
authors.initials: SE
authors.lastname: Gordon
authors.forename: J M
authors.initials: JM
authors.lastname: Lynch
authors.forename: M E
authors.initials: ME
authors.lastname: Pop
authors.forename: K L
authors.initials: KL
authors.lastname: Clark
mesh_terms: D019794:2,3-Diphosphoglycerate; D000136:Acid-Base Equilibrium; D000328:Adult; D000693:Anaerobiosis; D001639:Bicarbonates / Q000008:administration & dosage*; D001642:Bicycling; D002021:Buffers; D002336:Carnosine / Q000008:administration & dosage*; D004163:Diphosphoglyceric Acids / Q000097:blood*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D010710:Phosphates / Q000008:administration & dosage*
chemical_list: D001639:Bicarbonates; D002021:Buffers; D004163:Diphosphoglyceric Acids; D010710:Phosphates; D019794:2,3-Diphosphoglycerate; D002336:Carnosine