Glial repair at the lesion site in regenerating goldfish spinal cord: an immunohistochemical study using species-specific antibodies.
We have used fish-specific antibodies to show that repair in regenerating goldfish spinal cord is accompanied by the recovery of the astrocytic environment and restoration of the central canal. Astrocyte processes trailed the regenerated axons bridging the new cord, suggesting that they are not needed for axonal regrowth.
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Department of Optometry and Vision Sciences, University of Manchester Institute of Science and Technology, UK.
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D000818:Animals; D000918:Antibody Specificity; D001253:Astrocytes / Q000502:physiology; D001369:Axons / Q000502:physiology; D002417:Cattle / Q000276:immunology; D006054:Goldfish / Q000502:physiology*; D007150:Immunohistochemistry; D009186:Myelin Sheath / Q000378:metabolism; D009409:Nerve Crush; D009416:Nerve Regeneration / Q000502:physiology*; D009457:Neuroglia / Q000502:physiology*; D013045:Species Specificity; D013116:Spinal Cord / Q000166:cytology / Q000502:physiology*; D013119:Spinal Cord Injuries / Q000503:physiopathology; D014337:Trout / Q000276:immunology