title: [Pathological crying and unilateral pontine infarction].
abstract: A 64-year-old man presented with pathologic crying and right hemiplegia due to a unilateral pontine infarct from probable branch disease of the basilar artery. The circumscribed nature of the lesion was supported by MRI and short-latency evoked potentials. The weeping spells ceased after a few days of imipramine in low doses. Pathologic laughing and crying can be viewed as a limbic-motor disconnection syndrome, in which the faciovocal motor system is released from forebrain afferents carrying information of emotional content. The inclusion of pathologic laughing and crying in the syndrome pseudobulbar palsy is inaccurate and misleading, since each is related to distinct functional and anatomic systems intrinsic to the human brainstem.
authors.affiliation: Serviço de Clínica Médica C, Hospital Universitário Gaffrée, e Guinle, UNI-RIO (HUGG-UNI-RIO), Rio de Janeiro, Brasil.
authors.forename: R
authors.initials: R
authors.lastname: de Oliveira-Souza
authors.forename: W M
authors.initials: WM
authors.lastname: de Figueiredo
authors.forename: P A
authors.initials: PA
authors.lastname: Andreiuolo
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002544:Cerebral Infarction / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003448:Crying; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D000929:Antidepressive Agents, Tricyclic; D007099:Imipramine