Prostaglandin F2 alpha and E2 production into uterine lymph of pregnant and non-pregnant ewes.
Uterine lymphatic cannulation was performed in pregnant and non-pregnant ewes so that serial lymph samples could be analysed for prostaglandins (PGs) on day 12 to 18 after oestrus. The production of PGF2 alpha into uterine lymph showed peaks of > 1000 pg/h between days 14 and 18 of the oestrous cycle. Such peaks were either absent or much reduced (< 900 pg/h) over the same period in four pregnant animals. PGE2 production into uterine lymph remained low (< 510 pg/h) both in the four non-pregnant animals in the later part of the oestrous cycle and in three of four pregnant animals between days 14 to 18 post mating.
Bland
K P
KP
Department of Preclinical Veterinary Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Summerhall, UK.
Poyser
N L
NL
D000818:Animals; D015237:Dinoprost / Q000096:biosynthesis* / Q000378:metabolism; D015232:Dinoprostone / Q000096:biosynthesis* / Q000378:metabolism; D004971:Estrus / Q000378:metabolism; D005260:Female; D008196:Lymph / Q000378:metabolism*; D011247:Pregnancy; D012756:Sheep / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism*
D015237:Dinoprost; D015232:Dinoprostone