Preoperative strategies in the management of Wilms tumor.
Prenephrectomy therapy is well tolerated and results in easier operations, with significantly fewer tumor ruptures during surgery, and a favorable stage distribution as determined by the surgical specimen. As in other solid tumors of childhood, acceptable disease-free and actual survival figures with a minimum of early, intermediate, and late complications remain the aim of this strategy.
de Kraker
J
J
Department of Pediatric Oncology, Emma Kinderziekenhuis, University of Amsterdam, The Netherlands.
Weitzman
S
S
Voûte
P A
PA
D002170:Canada; D017024:Chemotherapy, Adjuvant; D006801:Humans; D007391:International Cooperation; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D009392:Nephrectomy; D011300:Preoperative Care / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D012955:Societies, Medical; D009396:Wilms Tumor / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*