title: [Anti-hemophilia drugs: from cryoprecipitate to factor VIII concentrates of high purity].
abstract: The methods have been surveyed concerning the isolation of concentrates of the factor VIII which are the drugs used in treatment of a hereditary disease--hemophilia. Prospects of improvement of these drugs have been considered, their characteristics (activity, purity, method of virus inactivation) are presented that permits one to orientate himself in a wide assortment of drugs, as well as to choose the concrete drug to be used in clinic.
authors.forename: A E
authors.initials: AE
authors.lastname: Gutsalo
authors.forename: T V
authors.initials: TV
authors.lastname: Varetskaia
authors.forename: E P
authors.initials: EP
authors.lastname: Kozulina
authors.forename: L P
authors.initials: LP
authors.lastname: Papaian
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D015925:Cryopreservation; D005169:Factor VIII / Q000302:isolation & purification / Q000627:therapeutic use*; D006467:Hemophilia A / Q000188:drug therapy*; D006358:Hot Temperature; D006801:Humans; D014841:von Willebrand Factor / Q000302:isolation & purification
chemical_list: D000998:Antiviral Agents; D014841:von Willebrand Factor; D005169:Factor VIII