title: The fate of bypass grafts to angiographically occult runoff vessels detected by magnetic resonance angiography.
abstract: OBJECTIVE
  Magnetic resonance angiography (MRA) is a noninvasive vascular imaging technique that is more sensitive than contrast arteriography (CA) for the detection of patent distal runoff vessels. This technique has facilitated performance of MRA-directed bypass procedures for patients who were believed not to be bypass candidates because of the absence of a suitable target vessel on the preoperative CA. The fate of bypasses to these angiographically occult runoff vessels is unknown, however, and it has been proposed that patients with angiographically occult runoff may have aggressive occlusive disease, rendering bypass procedures ultimately futile.
  
  
  METHODS
  Between April 1992 and February 1995, 212 autogenous vein infrageniculate bypasses were performed for limb-salvage indications, 22 (12%) to angiographically occult runoff vessels. Results of bypasses performed to angiographically occult vessels were compared with those of bypasses to CA-detected runoff vessels. Life-table analysis of graft-patency and limb-salvage rates was performed.
  
  
  RESULTS
  The accuracy of the MRA-predicted patency of angiographically occult vessels was confirmed in every case by the operative findings. Life-table analysis revealed no significant difference in primary graft patency (p > 0.05) or limb-salvage (p > 0.05) rates between patients with bypasses to runoff vessels seen by MRA alone. At 35 months after surgery, the primary graft patency rate was 68% for bypasses to CA-detected vessel bypass and 67% for MRA-detected vessels. The limb salvage rate was 83% for CA-detected vessel bypass patients and 78% for patients with angiographically occult runoff.
  
  
  CONCLUSIONS
  MRA can accurately identify patent runoff vessels not visualized by CA. Results of bypasses performed to angiographically occult runoff vessels are similar to those of bypasses performed to vessels detected by CA. MRA should be performed in patients in whom CA fails to reveal runoff vessels suitable for use in a limb-salvage procedure. The greater sensitivity of MRA may facilitate successful bypass surgery and improve the overall limb-salvage rate.
authors.affiliation: Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Carpenter
authors.forename: M A
authors.initials: MA
authors.lastname: Golden
authors.forename: C F
authors.initials: CF
authors.lastname: Barker
authors.forename: G A
authors.initials: GA
authors.lastname: Holland
authors.forename: R A
authors.initials: RA
authors.lastname: Baum
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000175:diagnosis*; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000601:surgery; D007866:Leg / Q000098:blood supply; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000175:diagnosis* / Q000601:surgery; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media