Effect of adding selegeline to levodopa in early, mild Parkinson's disease. Selegeline may be toxic in presence of increased dopamine concentrations.
Yu
P H
PH
Lai
C T
CT
Boulton
A A
AA
D000978:Antiparkinson Agents / Q000009:adverse effects*; D004298:Dopamine / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006801:Humans; D007980:Levodopa / Q000009:adverse effects*; D010300:Parkinson Disease / Q000188:drug therapy / Q000378:metabolism / Q000401:mortality*; D012642:Selegiline / Q000009:adverse effects*
D000978:Antiparkinson Agents; D012642:Selegiline; D007980:Levodopa; D004298:Dopamine