The anti-haemostatic strategies of the human hookworm Necator americanus.
The human hookworm Necator americanus appears to have evolved a number of complementary strategies to overcome the host's haemostatic processes. These include the inhibition of blood coagulation, platelet aggregation and mediator release, and the secretion of fibrinogenolytic enzymes. These strategies presumably allow the parasite to establish the chronic infections so often documented in human populations.
Furmidge
B A
BA
Department of Life Science, University of Nottingham.
Horn
L A
LA
Pritchard
D I
DI
D000818:Animals; D001777:Blood Coagulation; D005340:Fibrinogen; D006490:Hemostatics; D006790:Host-Parasite Interactions; D006801:Humans; D017221:Necator americanus / Q000502:physiology*; D010974:Platelet Aggregation
D006490:Hemostatics; D005340:Fibrinogen