Clinical assessment of oxygen delivery and consumption during hypotensive anaesthesia--a clinical application of The Deep Picture.
Usual evaluation of the relationship between oxygen delivery (DO2) and oxygen uptake (VO2) is based on the arterial oxygen tension (pO2), oxygen saturation (sO2), haemoglobin concentration (ctHb), the same indicators in mixed venous blood and cardiac output, sometimes supplemented by the expiratory carbon dioxide concentration. And, so far, the relationship among DO2, VO2 and the new parameters for an evaluation of oxygen status (oxygen extraction tension: px, concentration of extractable oxygen: cx, oxygen compensation factor: Qx) (1) has not been discussed enough. Therefore, this study was designed to evaluate whether the new parameters give the clinically significant information to analyse the relationship between DO2 and VO2 during the acute haemodynamic change with intentionally induced hypotension in anaesthetized adult patients.
Ueda
N
N
Department of Anaesthesiology, Kurume University School of Medicine, Fukuoka, Japan.
Muteki
T
T
Yamada
S
S
Masuda
Y
Y
D000328:Adult; D000527:Alprostadil / Q000494:pharmacology; D000768:Anesthesia, General; D001794:Blood Pressure / Q000187:drug effects; D002245:Carbon Dioxide / Q000032:analysis / Q000378:metabolism; D002302:Cardiac Output; D005260:Female; D006439:Hemodynamics; D006454:Hemoglobins / Q000032:analysis / Q000378:metabolism; D006801:Humans; D007023:Hypotension, Controlled; D008297:Male; D008875:Middle Aged; D009529:Nicardipine / Q000494:pharmacology; D005996:Nitroglycerin / Q000494:pharmacology; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption / Q000187:drug effects; D012119:Respiration; D014665:Vasodilator Agents / Q000494:pharmacology; D014680:Veins
D006454:Hemoglobins; D014665:Vasodilator Agents; D002245:Carbon Dioxide; D009529:Nicardipine; D000527:Alprostadil; D005996:Nitroglycerin; D010100:Oxygen