title: Chronic cholestasis of infancy.
abstract: This article focuses on the few disorders that produce chronic cholestasis in infants and children. Cholestasis is defined, and a framework for thinking about pathophysiology is provided. Medical management is discussed in the context of the consequences and complications of chronic cholestasis. The limited differential for chronic cholestasis is discussed, and approaches to diagnosis and management of specific disorders are provided.
authors.affiliation: Department of Pediatrics, University of Chicago, Pritzker School of Medicine, Illinois 60637-1470, USA.
authors.forename: P F
authors.initials: PF
authors.lastname: Whitington
mesh_terms: D002779:Cholestasis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011379:Prognosis