title: Bioactive isocoumarins and related metabolites from conifer endophytes.
abstract: Six new [1-4, 7, 9] and two known [6 and 8] metabolites have been isolated from culture filtrates of conifer endophyte strains of Canoplea elegantula. Their structures have been determined by spectroscopic means. Compound 1 was toxic to spruce budworm cells, and both 1 and 3 were toxic to spruce budworm larvae.
authors.affiliation: Department of Chemistry, University of New Brunswick, Fredericton, Canada.
authors.forename: J A
authors.initials: JA
authors.lastname: Findlay
authors.forename: S
authors.initials: S
authors.lastname: Buthelezi
authors.forename: R
authors.initials: R
authors.lastname: Lavoie
authors.forename: L
authors.initials: L
authors.lastname: Peña-Rodriguez
authors.forename: J D
authors.initials: JD
authors.lastname: Miller
mesh_terms: D000818:Animals; D002170:Canada; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D007814:Larva; D010947:Plants, Toxic / Q000737:chemistry*
chemical_list: D003374:Coumarins; D007306:Insecticides