title: Rationale for mutagenesis of DNA polymerase active sites: DNA polymerase alpha.
authors.affiliation: Department of Pathology, Stanford University School of Medicine, California 94305-5324, USA.
authors.forename: W C
authors.initials: WC
authors.lastname: Copeland
authors.forename: Q
authors.initials: Q
authors.lastname: Dong
authors.forename: T S
authors.initials: TS
authors.lastname: Wang
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D017124:Conserved Sequence; D004256:DNA Polymerase I / Q000737:chemistry; D004257:DNA Polymerase II / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism*; D017931:DNA Primers; D004261:DNA Replication; D004259:DNA-Directed DNA Polymerase / Q000096:biosynthesis / Q000737:chemistry*; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry; D054303:HIV Reverse Transcriptase; D015497:HIV-1 / Q000201:enzymology; D006801:Humans; D007700:Kinetics; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D012194:RNA-Directed DNA Polymerase / Q000737:chemistry; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000378:metabolism; D014764:Viral Proteins
chemical_list: D017931:DNA Primers; D011994:Recombinant Proteins; D014764:Viral Proteins; C062210:bacteriophage T7 RNA polymerase; D054303:HIV Reverse Transcriptase; D012194:RNA-Directed DNA Polymerase; D012321:DNA-Directed RNA Polymerases; D004256:DNA Polymerase I; D004257:DNA Polymerase II; D004259:DNA-Directed DNA Polymerase