Cellular fibroma of the ovary with Meigs' syndrome and elevated CA-125. A case report.
BACKGROUND
Cellular fibroma of the ovary is an uncommon benign tumor. When associated with Meigs' syndrome, it can produce a clinical picture similar to that of ovarian carcinoma.


METHODS
A 73-year-old nulligravida was admitted to the hospital with progressive cachexia, ascites, a right pleural effusion and a 15-cm pelvic mass. The serum CA-125 level was 1,780. Due to a high suspicion of ovarian carcinoma, the patient underwent exploratory laparotomy, total abdominal hysterectomy/bilateral salpingooophorectomy and surgical staging for a frozen section diagnosis of sarcoma. Permanent histology revealed the tumor to be a cellular fibroma, and the CA-125 levels fell to normal postoperatively.


CONCLUSIONS
Since benign ovarian tumors may mimic carcinoma, laparotomy and appropriate surgical staging are essential for the final diagnosis.
Siddiqui
M
M
Department of Medicine and Gynecology, Graduate Hospital, Philadelphia, Pennsylvania 19125, USA.
Toub
D B
DB
D000368:Aged; D002272:Carcinoembryonic Antigen / Q000097:blood*; D005260:Female; D005350:Fibroma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008539:Meigs Syndrome / Q000175:diagnosis* / Q000473:pathology
D002272:Carcinoembryonic Antigen