title: [A densitometric analysis of the chromatin structural characteristics of the nuclei in the peripheral blood lymphocytes of breast cancer patients].
abstract: Alterations in optical structural characteristics of nuclear chromatin, in comparison with healthy individuals (10) and patients with fibroadenoma (29), were detected in 57 patients with a breast cancer by densitometric investigation of peripheral blood lymphocytes. The degree of these alterations are closely associated with the level of malignancy in the initial neoplasia and the aggregation of oncopathology in pedigrees.
authors.forename: L A
authors.initials: LA
authors.lastname: Nalieskina
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000097:blood* / Q000235:genetics; D018270:Carcinoma, Ductal, Breast / Q000097:blood* / Q000235:genetics; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000097:blood* / Q000235:genetics; D002467:Cell Nucleus / Q000648:ultrastructure*; D002843:Chromatin / Q000648:ultrastructure*; D003720:Densitometry; D005260:Female; D018226:Fibroadenoma / Q000097:blood* / Q000235:genetics; D006801:Humans; D007399:Interphase; D008214:Lymphocytes / Q000648:ultrastructure*; D008875:Middle Aged; D010375:Pedigree
chemical_list: D002843:Chromatin