Doxorubicin in sterically stabilized liposomes.
Improved liposome stability and drug retention significantly increase the anticancer activity of encapsulated doxorubicin (Doxil), enhancing the effectiveness of chemotherapy and potentially reducing its toxicity.
Lasic
D D
DD
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage* / Q000494:pharmacology; D003110:Colonic Neoplasms / Q000188:drug therapy; D004317:Doxorubicin / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000494:pharmacology; D016503:Drug Delivery Systems; D005260:Female; D006801:Humans; D008081:Liposomes; D015674:Mammary Neoplasms, Animal / Q000188:drug therapy; D051379:Mice; D008854:Microscopy, Electron; D012514:Sarcoma, Kaposi / Q000188:drug therapy
D000903:Antibiotics, Antineoplastic; D008081:Liposomes; D004317:Doxorubicin