Cloning and expression of Xenopus laevis xSox12 cDNA.
A family of SRY-related genes has been termed SOX. We have isolated and sequenced a cDNA encoding xSox12 from Xenopus laevis ovary. The cDNA contained an open reading frame (ORF) coding for 470 amino acids encompassing an HMG box characteristic of the SOX family, a leucine zipper motif and glutamine-rich segments. The size of the xSox12 mRNA was determined to be 3.0 knt by Northern analysis. The ovary was the most prominent in the expression of the Sox mRNA among the various tissues of adult frog as far as examined.
Komatsu
N
N
Department of Anatomy, Keio University School of Medicine, Tokyo, Japan.
Hiraoka
Y
Y
Shiozawa
M
M
Ogawa
M
M
Aiso
S
S
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary; D004268:DNA-Binding Proteins / Q000096:biosynthesis* / Q000235:genetics*; D005260:Female; D015870:Gene Expression; D015723:Gene Library; D006609:High Mobility Group Proteins / Q000096:biosynthesis* / Q000235:genetics*; D016350:Leucine Zippers; D008297:Male; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D009928:Organ Specificity; D010053:Ovary / Q000378:metabolism; D029867:Xenopus Proteins; D014982:Xenopus laevis
D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D006609:High Mobility Group Proteins; C098537:Sox12 protein, Xenopus; D029867:Xenopus Proteins