Structures of nine oxygenated 4-methylene sterols from Hachijo marine sponge Theonella swinhoei.
Nine new sterols have been isolated from a marine sponge, Theonella swinhoei. Of these, seven sterols were found to be conicasterol derivatives [(24R)-4-methylene-24-methyl-8(14)-cholesten-3 beta-ol] oxygenated at carbon-7 and/or carbon-15. The other two were (24R)-7 beta,8 beta-epoxy-14 alpha-methoxy-4-methylene-24-methylcholestan- 3 beta-ol and (24R)-8,14-seco-8,14-dioxo-4-methylene-24-methylcholestan-3 beta-ol.
Sugo
Y
Y
Department of Chemistry, University of Tsukuba, Ibaraki, Japan.
Inouye
Y
Y
Nakayama
N
N
D000818:Animals; D002784:Cholesterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011161:Porifera / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013261:Sterols / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism
D013261:Sterols; C098158:conicasterol; D002784:Cholesterol