title: Pulmonary manifestations in the initial phase of schistosomiasis mansoni.
abstract: The clinical and radiological pulmonary manifestations in the initial phase of schistosomiasis mansoni were studied in thirty previously healthy individuals who were simultaneously infected. The findings were compared with those concerning a control group and related to possible pathogenetic factors. The respiratory manifestations were of light or of moderate intensity, the dry cough being the most common symptom. The significant radiological alterations were: thickening of bronchial walls and beaded micronodulation, predominantly localized in the lower pulmonary fields. It was observed significant association between wheezing and IgE levels, estimated by the area of immediate intradermal reaction, as well as between the number of blood eosinophils and the occurrence of radiological changes. Moreover, there was correlation between the worm burden and the presence of wheezing, thoracic pain and beaded micronodulation. Thus, the clinical and radiological pulmonary manifestations described are significant part of the initial phase of schistosomiasis mansoni and present the worm burden, eosinophilia and levels of IgE as probable pathogenetic factors.
authors.affiliation: Medical School, Federal University of Minas Gerais, Belo Horizonte, Brasil.
authors.forename: M O
authors.initials: MO
authors.lastname: Rocha
authors.forename: R L
authors.initials: RL
authors.lastname: Rocha
authors.forename: E R
authors.initials: ER
authors.lastname: Pedroso
authors.forename: D B
authors.initials: DB
authors.lastname: Greco
authors.forename: C S
authors.initials: CS
authors.lastname: Ferreira
authors.forename: J R
authors.initials: JR
authors.lastname: Lambertucci
authors.forename: N
authors.initials: N
authors.lastname: Katz
authors.forename: R S
authors.initials: RS
authors.lastname: Rocha
authors.forename: D F
authors.initials: DF
authors.lastname: Rezende
authors.forename: J
authors.initials: J
authors.lastname: Neves
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D008174:Lung Diseases, Parasitic / Q000000981:diagnostic imaging / Q000469:parasitology*; D008297:Male; D010270:Parasite Egg Count; D011859:Radiography; D012555:Schistosomiasis mansoni / Q000000981:diagnostic imaging / Q000469:parasitology*