title: Metastatic Crohn's disease.
abstract: The case of a 25-yr-old female with Crohn's disease who developed recurrent erythematous nodules on her lower extremities is described. These modules enlarged and ulcerated. Repeated bacterial, fungal, and acid-fast cultures remained negative. A skin biopsy revealed non-caseating granulomata, confirming the diagnosis of cutaneous "metastatic" Crohn's disease. The lesions completely resolved with systemic corticosteroid therapy. Although cutaneous metastatic Crohn's disease is uncommon, patients with Crohn's disease who develop unusual skin lesions that persist should have them biopsied.
authors.affiliation: Department of Medicine, University of Western Ontario, London, Canada.
authors.forename: P J
authors.initials: PJ
authors.lastname: Marotta
authors.forename: R P
authors.initials: RP
authors.lastname: Reynolds
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001706:Biopsy; D003424:Crohn Disease / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D011241:Prednisone / Q000008:administration & dosage; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011241:Prednisone