Gastrospirillum hominis-associated chronic active gastritis.
A 16-year-old Caucasian male presented with nausea, vomiting, and abdominal pain. Endoscopy revealed erythematous antral mucosa with four discrete gastric ulcers. Biopsies showed multiple spiral organisms, 4-6 microns in length, lying in the mucous layer on the surface. The organisms were strongly Giemsa positive and weakly CLOtest positive. They did not stain with Warthin-Starry silver or Gram-Weigert stains. Electron microscopy revealed fragments of Gastrospirillum hominis, with its characteristic spiral shape and length of 4 microns in the plane of section. We believe that this is one of the first reported pediatric cases in North America.
Akin
O Y
OY
Department of Pathology, Children's Hospital of the King's Daughters, Eastern Virginia Medical School, Norfolk 23507, USA.
Tsou
V M
VM
Werner
A L
AL
D000293:Adolescent; D001424:Bacterial Infections / Q000473:pathology*; D002908:Chronic Disease; D005756:Gastritis / Q000382:microbiology / Q000473:pathology*; D018247:Helicobacter heilmannii / Q000648:ultrastructure; D006801:Humans; D008297:Male; D011706:Pyloric Antrum / Q000382:microbiology / Q000473:pathology