Symbrachydactyly in Turner's syndrome.
In the report we describe the occurrence of symbrachydactyly of the right hand in an adult female with Turner syndrome and classical 45,X karyotype. Symbrachydactyly is a unilateral and sporadic hand malformation. The pathogenesis may be part of an arterial vascular disruption sequence, possibly secondary to fetal oedema which is an important and frequent symptom in the prenatal development of Turner syndrome foetusses.
De Smet
L
L
Orthopaedic Department, University Hospital Pellenberg, University of Leuven, Belgium.
Fryns
J P
JP
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005385:Fingers / Q000002:abnormalities; D006228:Hand Deformities, Congenital / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D014424:Turner Syndrome / Q000175:diagnosis / Q000235:genetics*