title: Selection of transplantation procedures and perioperative management in primary hyperoxaluria type 1.
abstract: This paper outlines the different options of transplant procedures in patients with primary hyperoxaluria type 1. Isolated kidney, isolated liver and combined liver-kidney grafting are discussed. Combined liver-kidney grafting appears to be the preferred treatment for patients already in end-stage renal failure. The potential value of the two other procedures is outlined. Guidelines for perioperative care are given. These involve fluid regime, pyridoxine supplementation, immunosuppression and administration of crystallization inhibitors such as phosphate and citrate. Special emphasis is put on selection of appropriate dialysis procedures and reasons why haemodialysis and continuous haemodiafiltration are the methods of choice.
authors.affiliation: Kinderklinik der Medizinischen Hochschule Hannover, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Latta
authors.forename: N V
authors.initials: NV
authors.lastname: Jamieson
authors.forename: J I
authors.initials: JI
authors.lastname: Scheinman
authors.forename: K
authors.initials: K
authors.lastname: Schärer
authors.forename: A
authors.initials: A
authors.lastname: Bensman
authors.forename: P
authors.initials: P
authors.lastname: Cochat
authors.forename: C
authors.initials: C
authors.lastname: Legendre
authors.forename: H
authors.initials: H
authors.lastname: Ruder
authors.forename: L
authors.initials: L
authors.lastname: de Pauw
authors.forename: C
authors.initials: C
authors.lastname: Toussaint
mesh_terms: D005440:Fluid Therapy; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000178:diet therapy / Q000188:drug therapy / Q000601:surgery*; D016030:Kidney Transplantation; D016031:Liver Transplantation; D011182:Postoperative Care; D011300:Preoperative Care; D006435:Renal Dialysis