Immune response, glucose metabolism, and performance of stressed feeder calves fed inorganic or organic chromium.
One hundred twenty-five Angus crossbred steers (215 +/- 2 kg initial BW) were blocked by weight and assigned to pens. Pens were randomly assigned to treatment (six pens/treatment). Treatments consisted of 1) control (no supplemental Cr), 2) CrCl3, 3) high-Cr yeast, or 4) Cr nicotinic acid complex. Chromium was added to provide .4 mg of supplemental Cr/kg of DM. Steers were fed diets containing 90% corn silage (DM basis) and 10% soybean meal-mineral-vitamin supplement. Steers were allowed to consume the diets on an ad libitum basis during the 56-d study. Performance was not affected by treatment. On d 52, steers supplemented with high-Cr yeast had a greater response to an intradermal injection of phytohemagglutin (PHA) for 8 h after injection than control steers (P < .10) or those supplemented with CrCl3 (P < .05) or Cr nicotinic acid (P < .05). Peripheral lymphocytes from steers supplemented with Cr nicotinic acid had a greater (P < .05) blastogenic response to 12.5 micrograms PHA/mL than lymphocytes from steers supplemented with CrCl3. After an i.v. infusion of glucose (.25 g of glucose/kg BW), plasma glucose tended (P < .11) to decrease at a faster rate from 15 to 45 min after infusion in steers fed Cr nicotinic acid. Steers supplemented with Cr nicotinic acid had greater (P < .05) serum insulin 15 and 30 min after infusion than those supplemented with CrCl3 and high-Cr yeast. Controls had lower serum insulin than those supplemented with Cr nicotinic acid 30 min after infusion.(ABSTRACT TRUNCATED AT 250 WORDS)
Kegley
E B
EB
Department of Animal Science, North Carolina State University, Raleigh 27695-7621, USA.
Spears
J W
JW
D000375:Aging / Q000276:immunology / Q000378:metabolism / Q000502:physiology; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects / Q000502:physiology; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology*; D002857:Chromium / Q000008:administration & dosage / Q000494:pharmacology*; D005527:Food, Fortified; D005947:Glucose / Q000378:metabolism*; D007111:Immunity, Cellular / Q000187:drug effects / Q000502:physiology; D007074:Immunoglobulin G / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D007328:Insulin / Q000097:blood; D008297:Male; D011897:Random Allocation; D012820:Silage; D013312:Stress, Physiological / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary*; D013997:Time Factors
D001786:Blood Glucose; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007328:Insulin; D002857:Chromium; D005947:Glucose