Origin of N18 and P14 far-fields of median nerve somatosensory evoked potentials studied in patients with a brain-stem lesion.
Somatosensory evoked potentials (SEPs) to median nerve stimulation were recorded in 3 patients with a brain-stem or medullary lesion documented by clinical and CT or MRI evidence. The positive P14 and negative N18 scalp far-fields were preserved. The results suggest that P14 reflects the spike volley in caudal medial lemniscus, and that the N18 neural generators are located in the medulla, probably in the dorsal column nuclei and/or the accessory inferior olives.
Noël
P
P
Department of Neurology, University of Brussels, Belgium.
Ozaki
I
I
Desmedt
J E
JE
D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000503:physiopathology; D001933:Brain Stem / Q000503:physiopathology*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008475:Median Nerve / Q000502:physiology*