title: MITOMAP: a human mitochondrial genome database.
abstract: We have developed a comprehensive database (MITOMAP) for the human mitochondrial DNA (mtDNA), the first component of the human genome to be completely sequenced [Anderson et al. (1981) Nature 290, 457-465]. MITOMAP uses the mtDNA sequence as the unifying element for bringing together information on mitochondrial genome structure and function, pathogenic mutations and their clinical characteristics, population associated variation, and gene- gene interactions. As increasingly larger regions of the human genome are sequenced and characterized, the need for integrating such information will grow. Consequently, MITOMAP not only provides a valuable reference for the mitochondrial biologist, it may also provide a model for the development of information storage and retrieval systems for other components of the human genome.
authors.affiliation: Department of Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Kogelnik
authors.forename: M T
authors.initials: MT
authors.lastname: Lott
authors.forename: M D
authors.initials: MD
authors.lastname: Brown
authors.forename: S B
authors.initials: SB
authors.lastname: Navathe
authors.forename: D C
authors.initials: DC
authors.lastname: Wallace
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003195:Computer Communication Networks; D004272:DNA, Mitochondrial; D016208:Databases, Factual; D015894:Genome, Human; D006801:Humans; D009154:Mutation
chemical_list: D004272:DNA, Mitochondrial