Endometrioid carcinoma of the endometrium with sertoliform differentiation.
Ovarian endometrioid tumors with areas mimicking sex cord-stromal tumors are well documented in the literature, but it is unclear whether a similar tumor occurs in the endometrium. We report here a patient with an endometrial endometrioid adenocarcinoma resembling a Sertoli cell tumor. Immunohistochemical and ultrastructural investigations proved it was an adenocarcinoma rather than a true sex cord-stromal tumor. The features of the endometrial tumor were similar to those described in ovarian endometrioid tumors mimicking sex cord-stromal tumors and we compare them to true sex cord-stromal cell tumors. This case confirms that endometrioid adenocarcinoma with sertoliform differentiation can arise in the endometrium as well as in the ovary.
Usadi
R S
RS
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.
Bentley
R C
RC
D000230:Adenocarcinoma / Q000473:pathology / Q000648:ultrastructure; D018269:Carcinoma, Endometrioid / Q000473:pathology* / Q000648:ultrastructure; D002454:Cell Differentiation; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012708:Sertoli Cells / Q000473:pathology*