title: [Synthesis of retinoids with a modified polar group and their antitumor activity. Report I].
abstract: Several retinoids with modified polar group were synthesized. Biological screening using HL-60 promyelocyte leukemia cells showed that the free carboxyl in the retinoid molecules is not the only group responsible for exhibiting the differentiating activity.
authors.forename: E L
authors.initials: EL
authors.lastname: Deriabina
authors.forename: A A
authors.initials: AA
authors.lastname: Khodonov
authors.forename: G V
authors.initials: GV
authors.lastname: Cherevataia
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Kirillova
authors.forename: V I
authors.initials: VI
authors.lastname: Shvets
authors.forename: I A
authors.initials: IA
authors.lastname: Kostanian
authors.forename: M V
authors.initials: MV
authors.lastname: Astapova
authors.forename: S M
authors.initials: SM
authors.lastname: Dranitsyna
authors.forename: E V
authors.initials: EV
authors.lastname: Starovoĭtova
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D002454:Cell Differentiation / Q000187:drug effects; D018922:HL-60 Cells; D006801:Humans; D011487:Protein Conformation; D018168:Receptors, Retinoic Acid / Q000737:chemistry; D012176:Retinoids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared
chemical_list: D000970:Antineoplastic Agents; D018168:Receptors, Retinoic Acid; D012176:Retinoids