[Synchronous manifestation of bladder inverted papilloma and transitional carcinoma of the renal pelvis].
OBJECTIVE
To review briefly the histological and biological aspects of inverted papilloma and to determine whether it is a benign tumor or low-grade malignant lesion.


RESULTS
We report a patient with synchronous presentation of bladder inverted papilloma and renal pelvis transitional cell carcinoma. After endoscopic resection of the bladder tumor and left ureteral meatus, a radical nephroureterectomy was carried out with success. The clinical features, diagnostic and therapeutic aspects are briefly reviewed.


CONCLUSIONS
Inverted papilloma accounts for 2.2% of all urothelial tumors; the bladder is most commonly involved. It is frequently a single lesion with endophytic growth pattern. The clinical significance remains a controversy. Most investigators consider them as benign neoplastic tumors, although in one third of the patients it may be associated with synchronous urothelial carcinomas, implying a malignant condition. Therapeutic management and follow-up are emphasized.
Pereira Arias
J G
JG
Servicio de Urología y Departamento de Anatomía Patológica, Hospital de Galdakao, Vizcaya, España.
Zabalza Estévez
I
I
Maraña Fernández
M
M
Escobal Tamayo
V
V
Catalina
A J
AJ
Paz Romeral
J L
JL
Ibarluzea González
J G
JG
Bernuy Malfaz
C
C
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis; D007682:Kidney Pelvis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D018308:Papilloma, Inverted / Q000175:diagnosis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis