Odor discrimination of "IP3-" and "cAMP-increasing" odorants in the turtle olfactory bulb.
The ability of the turtle olfactory system to discriminate between various odorants that increase levels of adenosine 3',5'-cyclic monophosphate (cAMP) and inositol trisphosphate (IP3) in the olfactory bulb was examined by the cross-adaptation technique and analyzed by multidimensional scaling. The mean values of the degree of discrimination among the IP3-increasing odorants were higher than those among the cAMP-increasing odorants, and were similar to those between cAMP- and IP3-increasing odorants, suggesting that the features of the receptors of cAMP-increasing odorants are different from those which respond to IP3-increasing odorants. Analysis by multidimensional scaling suggested that differences in second messenger pathways are not related to detecting odor quality in the turtle olfactory system.
Kashiwayanagi
M
M
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060, Japan.
Nagasawa
F
F
Inamura
K
K
Kurihara
K
K
D000080462:Acyclic Monoterpenes; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004192:Discrimination, Psychological; D045782:Hemiterpenes; D015544:Inositol 1,4,5-Trisphosphate / Q000378:metabolism*; D009570:Nitriles / Q000494:pharmacology; D009812:Odorants; D009830:Olfactory Bulb / Q000737:chemistry* / Q000502:physiology; D010421:Pentanoic Acids / Q000494:pharmacology; D011759:Pyrrolidines / Q000494:pharmacology; D018035:Receptors, Odorant / Q000032:analysis*; D013729:Terpenes / Q000494:pharmacology; D014426:Turtles / Q000033:anatomy & histology*
D000080462:Acyclic Monoterpenes; D045782:Hemiterpenes; D009570:Nitriles; D010421:Pentanoic Acids; D011759:Pyrrolidines; D018035:Receptors, Odorant; D013729:Terpenes; C008216:isovaleric acid; C054764:citralva; D015544:Inositol 1,4,5-Trisphosphate; D000242:Cyclic AMP; C007836:geraniol; C032519:pyrrolidine