MITOMAP: a human mitochondrial genome database.
We have developed a comprehensive database (MITOMAP) for the human mitochondrial DNA (mtDNA), the first component of the human genome to be completely sequenced [Anderson et al. (1981) Nature 290, 457-465]. MITOMAP uses the mtDNA sequence as the unifying element for bringing together information on mitochondrial genome structure and function, pathogenic mutations and their clinical characteristics, population associated variation, and gene- gene interactions. As increasingly larger regions of the human genome are sequenced and characterized, the need for integrating such information will grow. Consequently, MITOMAP not only provides a valuable reference for the mitochondrial biologist, it may also provide a model for the development of information storage and retrieval systems for other components of the human genome.
Kogelnik
A M
AM
Department of Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Lott
M T
MT
Brown
M D
MD
Navathe
S B
SB
Wallace
D C
DC
D000595:Amino Acid Sequence; D001483:Base Sequence; D003195:Computer Communication Networks; D004272:DNA, Mitochondrial; D016208:Databases, Factual; D015894:Genome, Human; D006801:Humans; D009154:Mutation
D004272:DNA, Mitochondrial