title: Triplet code-independent programming of living systems organisation by DNA: the link with intelligence and memory.
abstract: Previous suggestions from this laboratory (3), (a) that within its molecular electronic structure, DNA houses a computer-analog program of immense complexity, operating independently of, but complementary to, triplet coding and (b) that, inter alia, this program is the driving force for organising and executing the construction of species individuals in three dimensions, are extended in the present communication. It is now concluded that the DNA program also embodies an 'intelligence' component, which extends its organising ability both qualitatively and quantitatively beyond any of the heavily circumscribed 'self-organising' attributes claimed to be associated with naturally occurring inanimate systems. Further, that as part of the developmental process, a program component organises the fabrication of mammalian central nervous systems, including that of human beings with the associated attributes of intelligence, creativity and constructional skills. It is further suggested that the sophisticated random access memory system associated with human beings in particular may be explicable in terms of an extension of the DNA programming system: basically this involves the latter operating as computer-type 'hardware' for the storage of long-term memory and interacting with, primarily, glial cell RNA, acting as 'software' and storing short term traces. Finally, it is suggested that such an interrelationship between DNA/RNA molecular electronic structures can provide the necessary memory storage capacity and flexibility and also facilitates random access to the long-term DNA memory store.
authors.affiliation: Division of Life Sciences, King's College, London, UK.
authors.forename: D H
authors.initials: DH
authors.lastname: Adams
mesh_terms: D000818:Animals; D001483:Base Sequence; D001921:Brain / Q000502:physiology*; D002490:Central Nervous System / Q000502:physiology; D003062:Codon; D004247:DNA / Q000235:genetics*; D006801:Humans; D007360:Intelligence; D007858:Learning; D008322:Mammals; D008568:Memory; D008959:Models, Neurological; D008960:Models, Psychological; D009474:Neurons / Q000502:physiology; D012984:Software
chemical_list: D003062:Codon; D004247:DNA