title: Increased NOE enhancement in 1H decoupled 31P MRS.
abstract: 1H decoupling using the WALTZ-4 decoupling scheme is a popular means of improving spectral resolution in 31P NMR spectroscopy. At the same time, sensitivity in the proton decoupled 31P spectra is enhanced by the nuclear Overhauser effect. The authors show that when using WALTZ-4 decoupling in a uniform decoupler RF field, the degree of sensitivity enhancement is critically dependent on whether the decoupling interval contains an odd or an even number of WALTZ decoupling elements. This effect is demonstrated both in phantoms and in vivo.
authors.affiliation: Joint Department of Physics, Institute of Cancer Research, Sutton, Surrey, United Kingdom.
authors.forename: R
authors.initials: R
authors.lastname: van Sluis
authors.forename: G S
authors.initials: GS
authors.lastname: Payne
authors.forename: M O
authors.initials: MO
authors.lastname: Leach
mesh_terms: D006801:Humans; D007089:Image Enhancement / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D018482:Muscle, Skeletal / Q000378:metabolism; D019047:Phantoms, Imaging; D010759:Phosphorus Isotopes; D012680:Sensitivity and Specificity; D013997:Time Factors
chemical_list: D010759:Phosphorus Isotopes