title: Analgesic activity of Psychotria colorata (Willd. ex R. & S.) Muell. Arg. alkaloids.
abstract: An ethnopharmacological survey showed that home remedies prepared with flowers, fruits and roots of Psychotria colorata (Wild. ex R. & S.) Muell. Arg. (RUBIACEAE) are used by Amazonian caboclos as pain killers. These data led to the evaluation of analgesic activity of extracts of P. colorata, using the formalin, writhing and tail-flick methods. This paper reports the Naloxone reversible opioid-like analgesic activity of alkaloids present in leafs and flowers of P. colorata.
authors.affiliation: Departamento de Fisiologia, Universidade Federal do Pará, Belém, Brazil.
authors.forename: E
authors.initials: E
authors.lastname: Elisabetsky
authors.forename: T A
authors.initials: TA
authors.lastname: Amador
authors.forename: R R
authors.initials: RR
authors.lastname: Albuquerque
authors.forename: D S
authors.initials: DS
authors.lastname: Nunes
authors.forename: A do C
authors.initials: Ado C
authors.lastname: Carvalho
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D000700:Analgesics / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D000818:Animals; D001938:Brazil; D002845:Chromatography; D002855:Chromatography, Thin Layer; D005557:Formaldehyde; D006863:Hydrogen-Ion Concentration; D008297:Male; D051379:Mice; D010147:Pain Measurement; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011930:Reaction Time; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000470:Alkaloids; D000700:Analgesics; D005557:Formaldehyde