title: Trisomy among fetuses with noncoiled umbilical blood vessels.
abstract: OBJECTIVE
  To examine the relationship between trisomy and neonates with noncoiled umbilical blood vessels.
  
  
  METHODS
  The incidence of and risk factors for trisomy were evaluated among 48 consecutive, live-born neonates with noncoiled umbilical vessels.
  
  
  RESULTS
  Four cases (8.3%) of trisomy were identified. One case of mosaicism was also noted (2.1%). In no case was noncoiling of the umbilical vessels the only identifiable risk factor. The remaining 43 infants (89.6%) were phenotypically normal, although not all underwent karyotype analysis.
  
  
  CONCLUSIONS
  Noncoiled umbilical blood vessels alone do not appear to represent an independent risk factor for trisomy. Rather, identification of noncoiled blood vessels should prompt a thorough search for other abnormalities.
authors.affiliation: Division of Maternal Fetal Medicine, Good Samaritan Regional Medical Center, Phoenix, Arizona, USA.
authors.forename: T H
authors.initials: TH
authors.lastname: Strong
mesh_terms: D002901:Chromosomes, Human, 13-15; D004314:Down Syndrome; D006801:Humans; D007231:Infant, Newborn; D012189:Retrospective Studies; D012307:Risk Factors; D014314:Trisomy; D014471:Umbilical Veins