Poly(D,L-lactide) nanocapsules containing non-steroidal anti-inflammatory drugs: gastrointestinal tolerance following intravenous and oral administration.
Guterres
S S
SS
Laboratoire de Pharmacie Galénique et Biopharmacie, URA 1218, Faculté de Pharmacie, Université Paris XI, Châtenay-Malabry, France.
Fessi
H
H
Barratt
G
G
Puisieux
F
F
Devissaguet
J P
JP
D000284:Administration, Oral; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D002214:Capsules; D004008:Diclofenac / Q000008:administration & dosage / Q000009:adverse effects*; D004337:Drug Carriers; D007213:Indomethacin / Q000008:administration & dosage / Q000009:adverse effects*; D007262:Infusions, Intravenous; D007421:Intestine, Small / Q000187:drug effects*; D008297:Male; D011091:Polyesters; D051381:Rats; D017208:Rats, Wistar; D013270:Stomach / Q000187:drug effects*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002214:Capsules; D004337:Drug Carriers; D011091:Polyesters; D004008:Diclofenac; C033616:poly(lactide); D007213:Indomethacin