Chronic anaerobic bacterial endophthalmitis in pseudophakic rabbit eyes.
Experimental anaerobic bacterial endophthalmitis was produced in pseudophakic and aphakic rabbits by using anterior chamber inoculation of 2.5 x 10(6) Propionibacterium acnes organisms. Clinical inflammation was more intense and prolonged in operated eyes with an intraocular lens in place. The presence of an intraocular lens favors the development of chronic low-grade P. acnes-related inflammation.
Nobe
J R
JR
Department of Ophthalmology, USC School of Medicine, Los Angeles, USA.
Finegold
S M
SM
Rife
L L
LL
Edelstein
M A
MA
Smith
R E
RE
D000818:Animals; D001036:Aphakia, Postcataract / Q000150:complications; D001421:Bacteria, Anaerobic; D002908:Chronic Disease; D009877:Endophthalmitis / Q000382:microbiology* / Q000473:pathology; D015818:Eye Infections, Bacterial / Q000209:etiology* / Q000473:pathology; D016908:Gram-Positive Bacterial Infections / Q000209:etiology* / Q000473:pathology; D007910:Lenses, Intraocular / Q000009:adverse effects; D008297:Male; D011425:Propionibacterium acnes / Q000302:isolation & purification*; D011817:Rabbits