Skin side-effects of amiodarone therapy.
Amiodarone is a antiarrhythmic drug with many side-effects which include also the induction of photosensitivity and the development of greyish-blue pigmentations on the skin exposed to light. The authors examined 64 patients treated with amiodarone and 32 controls by means of a phototest using a xenon lamp. In 9.4% photosensitivity was recorded, in 9.4% there were greyish-blue hyperpigmentations in the face and on the back of the hands. Histological identification of these hyperpigmentations including electron microscopy was also performed.
Ettler
K
K
Gregor
J
J
Pidrman
V
V
Subrtová
D
D
Nozi cková
M
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000139:chemically induced*
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone