title: Prenylated isoflavanone from Erythrina eriotricha.
abstract: Bioassay-directed fractionation of a methylene chloride extract of the root bark of Erythrina eriotricha resulted in the isolation of a novel isoflavanone, named eriotrichin B, and the five known pterocarpans, isonorautenol, erybraedin A, erybraedin C, erybraedin D and erybraedin E. The structure of the new compound has been investigated by extensive spectroscopic studies, including 2D NMR and chemical evidence. The in vitro antimicrobial spectrum and potencies of the isolated compounds are also reported.
authors.affiliation: Department of Organic Chemistry, University of Yaounde, Cameroon.
authors.forename: A E
authors.initials: AE
authors.lastname: Nkengfack
authors.forename: J C
authors.initials: JC
authors.lastname: Vardamides
authors.forename: Z T
authors.initials: ZT
authors.lastname: Fomum
authors.forename: M
authors.initials: M
authors.lastname: Meyer
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004895:Erythrina; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D007529:Isoflavones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008752:Methylene Chloride; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts; D018517:Plant Roots; D010946:Plants, Medicinal; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development
chemical_list: D000900:Anti-Bacterial Agents; D001572:Benzofurans; D007529:Isoflavones; D010936:Plant Extracts; D008752:Methylene Chloride