Synthesis and antimicrobial properties of N-substituted halides of (E)-azastilbenols.
The synthesis of 15 new N-benzyl substituted derivatives of (E)-gamma-azastilbenols-2'(3' and 4') and their antimicrobial activity are reported. In particular, compounds 1a-c, 1h and 2a-b showed good antibacterial activity against Staphlococcus aureus.
Prukala
W
W
Wydzial Chemii Uniwersytet im. Adama Mickiewicza, Poznań, Polska.
Wyrzykiewicz
E
E
Kedzia
B
B
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents