title: Maintenance strategies in Crohn's disease.
abstract: Sooner or later, most patients require surgery, yet almost all experience a postoperative recurrence. Today, there is a new emphasis on medical prophylaxis. Available evidence indicates that 5-aminosalicylic acid is beneficial in this role, although high dosage is needed. The best strategy is to tailor treatment to the clinical pattern; for example, surgery is advised for repeated bouts of fibrostenosis and medication for inflammatory disease.
authors.affiliation: Mount Sinai School of Medicine, New York, N.Y., USA.
authors.forename: D B
authors.initials: DB
authors.lastname: Sachar
mesh_terms: D000636:Aminosalicylic Acids / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000188:drug therapy; D003131:Combined Modality Therapy; D003424:Crohn Disease / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D019804:Mesalamine; D011182:Postoperative Care; D012074:Remission Induction; D012460:Sulfasalazine / Q000627:therapeutic use
chemical_list: D000636:Aminosalicylic Acids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D012460:Sulfasalazine; D019804:Mesalamine