Burkholderia (Pseudomonas) cepacia as a cause of brain abscesses secondary to chronic suppurative otitis media.
A patient with a cholesteatoma secondary to chronic suppurative otitis media developed infective complications including cerebellar and cerebello-pontine abscesses. Burkholderia cepacia was isolated from ear swabs, infected tissue and surgical pus on five occasions over a six-month period. Despite exhibiting three different antibiotic susceptibility profiles, all five isolates were confirmed as clonally indistinguishable by pulsed-field gel electrophoresis. To the best of the authors' knowledge there are no previous reports of Burkholderia cepacia causing infection of the adult central nervous system.
Hobson
R
R
Department of Medical Microbiology, Aberdeen Royal Infirmary, Aberdeen Royal Hospitals NHS Trust, Foresterhill, UK.
Gould
I
I
Govan
J
J
D000328:Adult; D001922:Brain Abscess / Q000209:etiology* / Q000628:therapy; D016956:Burkholderia cepacia / Q000187:drug effects / Q000302:isolation & purification*; D002908:Chronic Disease; D006801:Humans; D008297:Male; D010035:Otitis Media, Suppurative / Q000150:complications*