title: Analysis of organic compounds in a case of suicide by ignition with lacquer thinner.
abstract: An autopsy case of suicide by ignition using lacquer thinner is presented. A wholly-charred body of a 54-year-old man and a can of lacquer thinner were found at the burnt driver's seat of a truck. Organic solvents in blood, urine, lung tissue, trachea and gastric contents and of the remaining clothes have been analyzed by gas chromatography/mass spectrometry (GC/MS). High levels of toluene, ethyl acetate and butyl acetate were detected in his clothes. The concentrations of toluene in the left and right heart blood, urine, gastric contents, squeeze sample and a block of lung tissue were 0.309, 0.226, 0.018, 0.051, and 0.268 mg/ml, and 0.340 mg/g, respectively. The ethanol levels in these samples were 1.89, 1.71, 1.58, 13.88 and 1.39 mg/ml, and 1.49 mg/g, respectively, and the profile suggested that the source of the ethanol was mainly drinking. The carboxyhemoglobin concentration in the left and right heart blood was 43.3 and 36.1%, respectively. The GC/MS data on organic solvents are consistent with the idea that he used the lacquer thinner contained in the can found in his truck for ignition. The high levels of toluene in his blood suggest that not only burns but also toluene poisoning contributed to his death.
authors.affiliation: Department of Legal Medicine, Kansai Medical University, Moriguchi, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yoshida
authors.forename: A
authors.initials: A
authors.lastname: Akane
authors.forename: Y
authors.initials: Y
authors.lastname: Okii
authors.forename: S
authors.initials: S
authors.lastname: Yoshimura
authors.forename: T
authors.initials: T
authors.lastname: Tokiyasu
authors.forename: T
authors.initials: T
authors.lastname: Watabiki
mesh_terms: D002263:Carboxyhemoglobin / Q000032:analysis; D000431:Ethanol / Q000032:analysis; D005554:Forensic Medicine; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D012997:Solvents / Q000032:analysis* / Q000506:poisoning*; D013405:Suicide; D014018:Tissue Distribution
chemical_list: D012997:Solvents; D000431:Ethanol; D002263:Carboxyhemoglobin