Heparin suppresses lipopolysaccharide-induced monocyte production of several cytokines, but simultaneously stimulates C3 production.
Høgåsen
A K
AK
Department of Pediatric Research, National Hospital, Oslo, Norway.
Abrahamsen
T G
TG
D000925:Anticoagulants / Q000494:pharmacology*; D002478:Cells, Cultured; D003176:Complement C3 / Q000096:biosynthesis* / Q000187:drug effects; D016207:Cytokines / Q000096:biosynthesis* / Q000187:drug effects; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008070:Lipopolysaccharides / Q000494:pharmacology*; D009000:Monocytes / Q000187:drug effects / Q000378:metabolism*
D000925:Anticoagulants; D003176:Complement C3; D016207:Cytokines; D008070:Lipopolysaccharides; D006493:Heparin