Rotavirus pathogenicity.
The pathogenicity of rotaviruses depends on multiple viral and host factors. In this review the evidence for the involvement of a number of viral genes in the ability to cause disease is presented. Different genes are of importance in different rotavirus-host systems: there is no single pathogenicity factor.
Burke
B
B
Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, United Kingdom.
Desselberger
U
U
D000818:Animals; D005814:Genes, Viral / Q000502:physiology; D006801:Humans; D012401:Rotavirus / Q000472:pathogenicity*; D012400:Rotavirus Infections / Q000821:virology