title: The hazards of synthetic (anthropogenic) chemicals.
abstract: Currently, there is a highly politicized debate on the comparative risks of naturally occurring and synthetic chemicals. Since humans are often exposed to complex mixtures of both classes of chemicals, the real-world value of this debate is unclear. However, in any such comparison, it is important to realize that some naturally occurring substances--such as lead or tobacco--have been so altered or disturbed by human activity that they are best considered as products of human activity, or anthropogenic. Reasons for concern over synthetic and anthropogenic chemicals include: persistence and propensity for long-term storage in biota and the environment; structural similarity to endogenous biomolecules; and additivity to natural hazards.
authors.affiliation: University of Maryland Medical School, Department of Epidemiology and Preventive Medicine, Baltimore 21201, USA.
authors.forename: E K
authors.initials: EK
authors.lastname: Silbergeld
mesh_terms: D006801:Humans; D018570:Risk Assessment; D014116:Toxicology