Selection of rainbow trout resistant to viral haemorrhagic septicaemia virus and transmission of resistance by gynogenesis.
In 1984 a programme of selection for resistance to viral haemorrhagic septicaemia virus (VHSV) in rainbow trout was initiated. The progenies of 14 males were submitted to a VHSV waterborne challenge. The mortality ranged from 30 to 95% and the heritability of resistance was estimated to be 0.63 +/- 0.26. One male consistently provided the most resistant offspring, and the second generation was produced from sires and dams selected among these families. The mean resistance improved and several females giving birth to resistant offspring were identified (0-10% mortality while the mortality in the controls was from 70 to 90%). The meiotic gynogenetic progeny of these females also demonstrated high resistance (mortality less than 10%). The role of superficial tissues in the resistance was confirmed and there was a striking difference in the growth of VHSV in fins excised and infected in vitro. The fins from resistant fish replicated the virus poorly as compared with the fins of susceptible fish.
Dorson
M
M
INRA, unité de virologie et d'immunologie moléculaires, pathologie infectieuse et immunité des poissons, Jouy-en-Josas, France.
Quillet
E
E
Hollebecq
M G
MG
Torhy
C
C
Chevassus
B
B
D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D005393:Fish Diseases; D007113:Immunity, Innate / Q000235:genetics; D008297:Male; D017686:Oncorhynchus mykiss / Q000235:genetics* / Q000821:virology*; D012209:Rhabdoviridae / Q000502:physiology*; D018353:Rhabdoviridae Infections / Q000276:immunology / Q000401:mortality / Q000662:veterinary*; D014766:Viremia / Q000276:immunology / Q000401:mortality / Q000662:veterinary*