title: Uterine leiomyosarcoma with clear cell areas.
abstract: An unusual case of a uterine leiomyosarcoma with a clear cell component in an 82-year-old woman who presented with vaginal bleeding and a mass protruding through the cervix is reported. Histologic examination of the biopsy sample showed only pleomorphic clear tumor cells and necrosis. Because the patient had a history of a breast carcinoma, and a computed tomography scan of the abdomen showed a renal cyst, these lesions created some problems in the differential diagnosis of the patient's clear cell neoplasm. The patient was treated with a hysterectomy, and examination of the uterus showed an epithelioid leiomyosarcoma with areas of clear cells. Four months after surgery, the patient presented with a vaginal recurrence, which was resected. Twelve months later, the patient had no evidence of recurrence.
authors.affiliation: Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
authors.forename: E G
authors.initials: EG
authors.lastname: Silva
authors.forename: C
authors.initials: C
authors.lastname: Tornos
authors.forename: N G
authors.initials: NG
authors.lastname: Ordóñez
authors.forename: M
authors.initials: M
authors.lastname: Morris
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology*; D012189:Retrospective Studies; D018227:Sarcoma, Clear Cell / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology*