title: Mutations in tumour suppressor gene p53 in two feline fibrosarcomas.
abstract: Exons 5-7 of the tumour suppressor gene p53 were investigated in genomic DNA of tumours of domestic cats. In one fibrosarcoma investigated we observed a mutation GAG-->AAG (glutamic acid-->lysine) in codon 180; in another there was a mutation CGG-->TGG (arginine-->tryptophane) in codon 248.
authors.affiliation: Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria.
authors.forename: B
authors.initials: B
authors.lastname: Mayr
authors.forename: G
authors.initials: G
authors.lastname: Schaffner
authors.forename: R
authors.initials: R
authors.lastname: Kurzbauer
authors.forename: A
authors.initials: A
authors.lastname: Schneider
authors.forename: M
authors.initials: M
authors.lastname: Reifinger
authors.forename: G
authors.initials: G
authors.lastname: Loupal
mesh_terms: D000818:Animals; D001483:Base Sequence; D002371:Cat Diseases / Q000235:genetics*; D002415:Cats; D005354:Fibrosarcoma / Q000235:genetics / Q000662:veterinary*; D016158:Genes, p53 / Q000235:genetics*; D008297:Male; D008969:Molecular Sequence Data; D017354:Point Mutation / Q000235:genetics*