title: Adaptation of the temporomandibular joint to altered mandibular function.
abstract: This pilot study describes responses of Sprague Dawley rats to mandibular retrusion. Lingually overcontoured crowns were cemented onto maxillary incisors to produce 3.5 mm of autoretrusion. Monitoring data indicate that activity was suppressed and nutritional intake was reduced. Histological evaluation of the 2-, 4-, 7-, and 59-day test specimens detected only a monocytic infiltrate response in the 4-day group.
authors.affiliation: College of Dentistry, University of Oklahoma, Oklahoma City, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Johnson
authors.forename: J W
authors.initials: JW
authors.lastname: Brand
authors.forename: S K
authors.initials: SK
authors.lastname: Young
authors.forename: M G
authors.initials: MG
authors.lastname: Duncanson
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001522:Behavior, Animal; D003769:Dental Occlusion, Traumatic / Q000150:complications* / Q000503:physiopathology; D016014:Linear Models; D008313:Malocclusion, Angle Class III / Q000150:complications / Q000503:physiopathology; D008335:Mandibular Condyle / Q000473:pathology; D009043:Motor Activity; D018485:Muscle Fibers, Skeletal / Q000473:pathology; D010865:Pilot Projects; D011626:Pterygoid Muscles / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D063173:Retrognathia / Q000150:complications / Q000503:physiopathology; D013704:Temporomandibular Joint / Q000473:pathology* / Q000503:physiopathology; D013705:Temporomandibular Joint Disorders / Q000209:etiology*; D015430:Weight Gain; D015431:Weight Loss