Cloning and characterization of two transcripts generated from the mel-13 gene positioned adjacent to the mammalian Polycomb group-related gene mel-18.
We previously isolated the mel-18 gene, a mammalian Polycomb group (PcG)-related gene with homology to bmi-1 oncogene. We show in this paper the existence of a new gene, mel-13, which overlapped with the mel-18 anti-oncogene. We discuss the relationships between mel-13 and the mel-18, bup, and Su(z)2 genes.
Tetsu
O
O
Division of Molecular Immunology, Center for Biomedical Science, Chiba University, Japan. Chiba University, Japan.
Kanno
R
R
Isono
K
K
Taniguchi
M
M
Kanno
M
M
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004330:Drosophila / Q000235:genetics; D029721:Drosophila Proteins; D007301:Insect Hormones / Q000235:genetics; D007506:Iron-Sulfur Proteins; D008322:Mammals; D024101:Mitochondrial Proteins; D008969:Molecular Sequence Data; D005810:Multigene Family; D063150:Polycomb Repressive Complex 1; D014176:Protein Biosynthesis; D011506:Proteins / Q000737:chemistry / Q000235:genetics*; D015183:Restriction Mapping; D017386:Sequence Homology, Amino Acid; D014158:Transcription, Genetic
C098536:Cisd3 protein, mouse; D029721:Drosophila Proteins; D007301:Insect Hormones; D007506:Iron-Sulfur Proteins; D024101:Mitochondrial Proteins; C066770:Pc protein, Drosophila; D011506:Proteins; D063150:Polycomb Repressive Complex 1