Mycobacterium tuberculosis infection in an orangutan (Pongo pygmaeus).
A respiratory disorder was noted in a 5-year-old female orangutan kept in the Yongin Farmland. Radiographically, multiple radiodense foci ranging from 2 to 6 mm diameter were seen throughout the lung lobes. Grossly, the thoracic cavity revealed a firm texture and grayish-pink discoloration of the left apical lung lobe. Histopathologically, multifocal areas of granulomatous pneumonia present the right and left apical lung lobes. Both primers from IS1081 and IS6110 targeting 196 bp and 245 bp respectively were used in polymerase chain reaction, Mycobacterium tuberculosis was isolated from liver and confirmed by polymerase chain reaction.
Shin
N S
NS
Yongin Farmland, Samsung Joong-Ang Development, Republic of Korea.
Kwon
S W
SW
Han
D H
DH
Bai
G H
GH
Yoon
J
J
Cheon
D S
DS
Son
Y S
YS
Ahn
K
K
Chae
C
C
Lee
Y S
YS
D000818:Animals; D018420:Ape Diseases / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D001483:Base Sequence; D017931:DNA Primers / Q000032:analysis / Q000737:chemistry / Q000235:genetics; D004269:DNA, Bacterial / Q000032:analysis / Q000737:chemistry / Q000235:genetics; D005260:Female; D007723:Korea / Q000453:epidemiology; D008099:Liver / Q000737:chemistry / Q000382:microbiology; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D008969:Molecular Sequence Data; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D011148:Pongo pygmaeus / Q000382:microbiology*; D011859:Radiography; D014376:Tuberculosis / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*
D017931:DNA Primers; D004269:DNA, Bacterial