title: Synthesis and antimicrobial activity of 7 beta-[N-(arylmethyloxyimino) acetamido]cephalosporanic acid derivatives.
abstract: Some cephalosporanic acid derivatives substituted on the C(7) amino nitrogen with (arylmethyloxyimino)acetyl moieties were synthesized and tested in vitro for their antimicrobial activity against Gram positive and Gram negative bacteria. The new compounds showed a modest activity directed only against Gram positive microorganisms.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università di Pisa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Macchia
authors.forename: E
authors.initials: E
authors.lastname: Menchini
authors.forename: E
authors.initials: E
authors.lastname: Orlandini
authors.forename: A
authors.initials: A
authors.lastname: Rossello
authors.forename: G
authors.initials: G
authors.lastname: Broccali
authors.forename: M
authors.initials: M
authors.lastname: Visconti
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D002511:Cephalosporins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests
chemical_list: D002511:Cephalosporins