title: Systemic and cerebral vasculitis coexisting with disseminated coagulopathy in systemic lupus erythematosus associated with antiphospholipid syndrome.
abstract: Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are closely related, but each has it own characteristic vasculopathy: vasculitis in SLE and thrombosis in APS, and either may be a serious or life threatening complication. When a patient has SLE associated with APS, systemic and cerebral vasculitis may coexist with disseminated coagulopathy. We report this complication in a 60-year-old woman who died from stroke and myocardial infarction, an occurrence seldom documented in the literature.
authors.affiliation: Department of Pathology, University of California Davis Medical Center, Sacramento 95817, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Lie
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Tokano
authors.forename: H
authors.initials: H
authors.lastname: Hashimoto
mesh_terms: D016736:Antiphospholipid Syndrome / Q000150:complications*; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000473:pathology; D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D014657:Vasculitis / Q000150:complications* / Q000473:pathology