title: The genetics of pain and pain inhibition.
abstract: The present review summarizes the current state of knowledge about the genetics of pain-related phenomena and illustrates the scope and power of genetic approaches to the study of pain. We focus on work performed in our laboratories in Jastrzebiec, Poland; Portland, OR; and Los Angeles, which we feel demonstrates the continuing usefulness of classical genetic approaches, especially when used in combination with newly available molecular genetic techniques.
authors.affiliation: Department of Psychology, University of California, Los Angeles, 90095-1563, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Mogil
authors.forename: W F
authors.initials: WF
authors.lastname: Sternberg
authors.forename: P
authors.initials: P
authors.lastname: Marek
authors.forename: B
authors.initials: B
authors.lastname: Sadowski
authors.forename: J K
authors.initials: JK
authors.lastname: Belknap
authors.forename: J C
authors.initials: JC
authors.lastname: Liebeskind
mesh_terms: D000698:Analgesia; D000818:Animals; D003433:Crosses, Genetic; D019389:Cytochrome P-450 CYP2D6; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics; D006801:Humans; D015141:Los Angeles; D051379:Mice; D008815:Mice, Inbred Strains; D006899:Mixed Function Oxygenases / Q000235:genetics; D008957:Models, Genetic; D010146:Pain / Q000235:genetics* / Q000503:physiopathology* / Q000517:prevention & control; D010465:Perception; D017354:Point Mutation; D011044:Poland; D011995:Recombination, Genetic
chemical_list: D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D019389:Cytochrome P-450 CYP2D6