[Dolichol-coupled biosynthesis of an oligosaccharide precursor for N-glycosylated proteins in the rough endoplasmic reticulum].
Data from literature concerning the structure and function of enzymes, taking part in dolichol-coupled biosynthesis of oligosaccharide precursor, which is used for N-glycosylation of protein in endoplasmic reticulum of eukaryotic cells, are summarized and analyzed in the review. The mechanisms of translocation of dolichol and its derivatives through membrane are discussed. The data about topography of reactions of "dolichol cycle", taking place on cytoplasmic and luminal surfaces of endoplasmic reticulum membrane, are considered.
Shpakov
A O
AO
D000595:Amino Acid Sequence; D000818:Animals; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D004288:Dolichol Phosphates / Q000502:physiology*; D018870:Endoplasmic Reticulum, Rough / Q000378:metabolism*; D006031:Glycosylation; D006801:Humans; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000096:biosynthesis* / Q000737:chemistry; D011506:Proteins / Q000737:chemistry*
D004288:Dolichol Phosphates; D009844:Oligosaccharides; D011506:Proteins