The prognostic significance of DNA ploidy in adenocarcinomas of the esophagogastric junction.
DNA aneuploidy, as determined by flow cytometry, was detected in 36 out of 59 adenocarcinomas of the esophagogastric junction (61.0%). DNA aneuploidy was more frequent in tumors with infiltrative growth pattern and in high pT categories. No correlation was found with pN category, grading and Laurén's classification. In contrast to clinicopathological parameters, DNA ploidy has no impact on patients survival in univariate survival analysis.
Sarbia
M
M
Department of Pathology, Heinrich-Heine University, Düsseldorf, Germany.
Molsberger
G
G
Willers
R
R
Horstmann
O
O
Schroders
C
C
Porschen
R
R
Gabbert H
E
E
D000230:Adenocarcinoma / Q000235:genetics*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004938:Esophageal Neoplasms / Q000235:genetics*; D004943:Esophagogastric Junction; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D011379:Prognosis; D013274:Stomach Neoplasms / Q000235:genetics*; D016019:Survival Analysis