Severe hypercalcemia following neonatal liver transplantation.
A 3-week-old infant with liver failure underwent an orthotopic liver transplant. Following a prolonged second surgical procedure in which he received massive amounts of blood products, his serum calcium was 31.3. mg/dl (7.8 mmol/l). This patient represents a case of severe hypercalcemia secondary to intraoperative calcium infusions given in an effort to overcome infusion-related citrate toxicity in a neonate with hepatic dysfunction.
Bartosh
S M
SM
Department of Pediatrics, University of Chicago Pritzker School of Medicine, Chicago, Ill, USA.
Sprague
S M
SM
Nakagawa
Y
Y
Baron
B W
BW
Aronson
A J
AJ
D000925:Anticoagulants / Q000506:poisoning; D002118:Calcium / Q000627:therapeutic use; D002951:Citrates / Q000506:poisoning; D019343:Citric Acid; D017707:Erythrocyte Transfusion / Q000009:adverse effects; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D007231:Infant, Newborn; D007430:Intraoperative Care; D016031:Liver Transplantation; D008297:Male; D017713:Platelet Transfusion / Q000009:adverse effects; D011183:Postoperative Complications; D065227:Transfusion Reaction
D000925:Anticoagulants; D002951:Citrates; D019343:Citric Acid; D002118:Calcium