Merkel cell carcinoma of the eyelid.
OBJECTIVE
To demonstrate the clinical variability and histologic characteristics of Merkel cell carcinoma of the eyelid.


METHODS
We investigated two cases of Merkel cell carcinoma of the eyelid in a 67-year-old man and an 83-year-old woman, respectively. Both lesions were initially misdiagnosed as benign tumors on clinical examination.


RESULTS
After the correct diagnosis was made, both lesions were treated with wide resection aided by frozen sections, and reconstructive surgery.


CONCLUSIONS
Merkel cell carcinoma is an aggressive tumor with variable clinical manifestation. Radical surgical therapy and close follow-up are indicated.
Soltau
J B
JB
Departments of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.
Smith
M E
ME
Custer
P L
PL
D000368:Aged; D000369:Aged, 80 and over; D015266:Carcinoma, Merkel Cell / Q000201:enzymology / Q000473:pathology* / Q000601:surgery; D005142:Eyelid Neoplasms / Q000201:enzymology / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D012878:Skin Neoplasms / Q000201:enzymology / Q000473:pathology* / Q000601:surgery
D010751:Phosphopyruvate Hydratase