Preservation of renal function and the risk of hyperfiltration nephropathy.
The long-term impact of unilateral nephrectomy on renal function has been reviewed in patients who have undergone donor nephrectomy or nephrectomy in childhood as a result of unilateral renal disease. there has been no adverse impact on renal function. In the setting of a normal contralateral kidney, and in the absence of any urologic or systemic disorder that may affect future renal function, it is not necessary to perform nephron-sparing surgery for the purpose of preservation of renal function.
Goldfarb
D A
DA
Department of Urology, Cleveland Clinic-Foundation, OH 44195, USA.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000502:physiology; D007680:Kidney Neoplasms / Q000503:physiopathology / Q000601:surgery*; D016030:Kidney Transplantation; D008875:Middle Aged; D009392:Nephrectomy / Q000009:adverse effects* / Q000379:methods; D014019:Tissue Donors