Late effects of treatment for Wilms tumor.
Successfully treated patients may be at risk for a variety of organ-specific complications, depending upon the treatment administered. Former patients should be carefully screened for such complications to facilitate early intervention. Additional research is necessary to define more accurately the frequency of these complications, to identify techniques for screening of childhood cancer survivors, and to develop therapeutic regimens of equal efficacy but lower potential for long-term morbidity.
Green
D M
DM
Roswell Park Cancer Institute, Buffalo, New York, USA.
Donckerwolcke
R
R
Evans
A E
AE
D'Angio
G J
GJ
D000970:Antineoplastic Agents / Q000009:adverse effects*; D004249:DNA Damage; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics / Q000401:mortality / Q000628:therapy*; D016609:Neoplasms, Second Primary / Q000209:etiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D011878:Radiotherapy / Q000009:adverse effects; D015996:Survival Rate; D009396:Wilms Tumor / Q000235:genetics / Q000401:mortality / Q000628:therapy*
D000970:Antineoplastic Agents