title: Evaluation of certain veterinary drug residues in food. Forty-third report of the Joint FAO/WHO Expert Committee on Food Additives.
abstract: This report presents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in foods. The first part of the report considers the evaluation of veterinary drugs with a long history of use and the implications of veterinary drug use in aquaculture, and discusses the need for adequate data. A summary follows of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: a beta-adrenoceptor-blocking agent (carazolol), seven antimicrobial agents (dihydrostreptomycin and streptomycin, enrofloxacin, gentamicin, neomycin, oxolinic acid and spiramycin) a glucocorticosteroid (dexamethasone), and a tranquilizing agent (azaperone). Annexed to the report are a summary of the Committee's recommendations on these drugs, including Acceptable Daily intakes and Maximum Residue Limits, and a list of further toxicological studies and other information required or desired.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000032:analysis; D000617:Aminoglycosides; D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000032:analysis; D000890:Anti-Infective Agents / Q000378:metabolism; D000892:Anti-Infective Agents, Urinary / Q000009:adverse effects / Q000032:analysis; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000032:analysis; D002417:Cattle; D002645:Chickens; D004350:Drug Residues / Q000009:adverse effects / Q000032:analysis* / Q000592:standards; D005069:Evaluation Studies as Topic; D024841:Fluoroquinolones; D005506:Food Contamination / Q000032:analysis*; D005938:Glucocorticoids / Q000009:adverse effects / Q000032:analysis; D006736:Horses; D006801:Humans; D018942:Macrolides; D012756:Sheep; D013552:Swine; D013557:Switzerland; D014480:United Nations; D014944:World Health Organization
chemical_list: D000319:Adrenergic beta-Antagonists; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000892:Anti-Infective Agents, Urinary; D014150:Antipsychotic Agents; D024841:Fluoroquinolones; D005938:Glucocorticoids; D018942:Macrolides