title: The function of free jejunal autografts in the pharyngo-oesophageal segment.
abstract: Eight patients were studied 6 weeks to 16 months following pharyngo-oesophageal reconstruction using a free jejunal interposition graft. Ambulatory manometry was carried out using an intraluminal strain gauge assembly linked to a portable microprocessor. In one patient, the assembly could not be passed because of a redundant jejunal loop. In four subjects, the jejunal interposition appeared to function as a passive conduit with very little manometric activity. In the remaining three patients, however, there was evidence of both propagated peristaltic waves within the graft and regular contractile activity, characteristic of Phase III of the intestinal Migrating Motor Complex (MMC). The presence of MMC activity at only 7 weeks following surgery confirms its independence of extrinsic intestinal innervation. Spontaneous contractile activity, however, was not interrupted by propagated water swallows and may contribute to post-operative dysphagia in some individuals.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Royal Infirmary, Glasgow.
authors.forename: J A
authors.initials: JA
authors.lastname: Wilson
authors.forename: A G
authors.initials: AG
authors.lastname: Maran
authors.forename: A
authors.initials: A
authors.lastname: Pryde
authors.forename: W S
authors.initials: WS
authors.lastname: Walker
authors.forename: R C
authors.initials: RC
authors.lastname: Heading
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D004944:Esophagoplasty / Q000379:methods*; D004947:Esophagus / Q000502:physiology; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000601:surgery; D007583:Jejunum / Q000637:transplantation*; D008297:Male; D008365:Manometry; D008875:Middle Aged; D010614:Pharynx / Q000601:surgery*; D014182:Transplantation, Autologous