Complete regression of villous adenomas of the colon using piroxicam, a nonsteroidal anti-inflammatory drug.
A 73-year old patient with a past history of rectal carcinoma was found to have two sessile villous adenomas of the cecum. Because he refused surgical resection, a course of nonsteroidal anti-inflammatory drug therapy using piroxicam was given, and the villous adenomas regressed within three months. The cecum has remained clear at one year.
Gowen
G F
GF
Department of Surgery, Pennsylvania Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
D018253:Adenoma, Villous / Q000188:drug therapy* / Q000473:pathology; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002430:Cecal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D003113:Colonoscopy; D006801:Humans; D008297:Male; D010894:Piroxicam / Q000627:therapeutic use*; D012074:Remission Induction
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010894:Piroxicam