title: [Chronobiology of depression].
abstract: Depressive signs and symptoms can change on a daily, monthly and annual scale (diurnal variation of mood, premenstrual dysphoric disorder, seasonal affective disorders). This can be understood as a coupling of psychopathology to pre-existing rhythmic processes (association hypothesis). Also early morning awakening, short REM-sleep-latencies and the antidepressive effects of sleep deprivation and of phase advance therapy bear no evidence of a particular chronopathology in depression. Correspondingly, most studies in depressives have not shown an abnormal phasing of circadian rhythms.
authors.affiliation: Psychiatrischen Klinik, Universität Tübingen, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Giedke
mesh_terms: D000339:Affect / Q000502:physiology; D001683:Biological Clocks / Q000502:physiology*; D003866:Depressive Disorder / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy; D005260:Female; D006801:Humans; D017286:Polysomnography; D011293:Premenstrual Syndrome / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D011603:Psychophysiology; D011930:Reaction Time / Q000502:physiology; D016574:Seasonal Affective Disorder / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D012892:Sleep Deprivation / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology