title: Plasma lipids, lipoproteins and apolipoproteins in hirsute women.
abstract: OBJECTIVE
  To determine whether lipid alterations in hirsute women are due to excessive androgen, low estrogen or to a combination of these abnormalities.
  
  
  METHODS
  Cross sectional study.
  
  
  METHODS
  Forty-five hirsute women between 15 and 39 years of age.
  
  
  METHODS
  FSH, LH, 17beta-estradiol, PRL, testosterone, androstenedione, triglycerides and apolipoproteins A-I and B.
  
  
  RESULTS
  Testosterone was correlated with triglycerides (r: 0.76, p<0.01), HDL (r: -0.61, P<0.01) and LDL (r: 0.50, p<0.05). Both HDL (r: 0.66, p<0.01) and LDL (r: -0.57, p<0.01) were correlated with estradiol. Total cholesterol was also correlated with estradiol (r: -0.52, p<0.05). Cross adjusted correlations revealed that, after adjusting for estradiol, lipids were associated with testosterone and that estradiol was also correlated with lipids when adjusted for testosterone.
  
  
  CONCLUSIONS
  The results suggest that altered lipids in women with hyperandrogenism could result from independent effects of androgens and estrogens.
authors.affiliation: Department of Gynaecology and Obstetrics, Hospital Clinic i Provincial, Barcelona, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Castelo-Branco
authors.forename: E
authors.initials: E
authors.lastname: Casals
authors.forename: M J
authors.initials: MJ
authors.lastname: Martinez de Osaba
authors.forename: C
authors.initials: C
authors.lastname: Sanllehy
authors.forename: A
authors.initials: A
authors.lastname: Fortuny
mesh_terms: D000293:Adolescent; D000328:Adult; D000728:Androgens / Q000097:blood*; D000735:Androstenedione / Q000097:blood; D001053:Apolipoproteins / Q000097:blood*; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology; D002784:Cholesterol / Q000097:blood; D003430:Cross-Sectional Studies; D004967:Estrogens / Q000097:blood*; D005260:Female; D006628:Hirsutism / Q000097:blood*; D006801:Humans; D017588:Hyperandrogenism / Q000097:blood*; D008055:Lipids / Q000097:blood*; D011247:Pregnancy; D012307:Risk Factors; D013739:Testosterone / Q000097:blood; D014280:Triglycerides / Q000097:blood*
chemical_list: D000728:Androgens; D001053:Apolipoproteins; D004967:Estrogens; D008055:Lipids; D014280:Triglycerides; D013739:Testosterone; D000735:Androstenedione; D002784:Cholesterol