title: Ocular tumoral calcinosis. A clinicopathologic study.
abstract: Tumoral calcinosis is a rare systemic disorder characterized by para-articular ectopic soft-tissue calcification. This case report describes the ophthalmic features (palpebral conjunctival calcific nodules, the white limbal girdle of Vogt, disc drusen, and angioid streaks) in a 38-year-old Asian woman who had tumoral calcinosis associated with hyperphosphatemia. A morphologic study of the calcified nodules on the palpebral conjunctiva disclosed deposition of hydroxyapatite crystals in an extracellular matrix (deposit) containing alcianophilic mucopolysaccharides. Excision of the eyelid nodules was not followed by recurrence.
authors.affiliation: Tennent Institute of Ophthalmology, Western Infirmary, Glasgow, Scotland.
authors.forename: F
authors.initials: F
authors.lastname: Ghanchi
authors.forename: A
authors.initials: A
authors.lastname: Ramsay
authors.forename: S
authors.initials: S
authors.lastname: Coupland
authors.forename: D
authors.initials: D
authors.lastname: Barr
authors.forename: W R
authors.initials: WR
authors.lastname: Lee
mesh_terms: D000328:Adult; D000793:Angioid Streaks / Q000473:pathology; D002114:Calcinosis / Q000097:blood / Q000473:pathology* / Q000601:surgery; D003229:Conjunctival Diseases / Q000097:blood / Q000473:pathology* / Q000601:surgery; D017886:Durapatite; D005141:Eyelid Diseases / Q000097:blood / Q000473:pathology* / Q000601:surgery; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D015594:Optic Disk Drusen / Q000473:pathology; D010710:Phosphates / Q000097:blood
chemical_list: D010710:Phosphates; D017886:Durapatite