[Laboratory indicators in drug addicts and tertiary prevention of narcotic dependence].
BACKGROUND
The authors report on some laboratory indicators in opiate abusers dependent for prolonged periods on opiates. The objective of the study is a proposal for an examination pattern in adepts during oral substitution therapy and emphasis on the necessity of systematic follow up of the health status.


RESULTS
In 27 opiate abusers with a varying period of dependence on opiates the hematology laboratory tests was assessed, plasma levels of some minerals, renal and hepatic functions, some enzymes and metabolic indicators and vitamin D metabolites. For statistical evaluation Student's t-test was used and simultaneous testing.


CONCLUSIONS
Long-term opiate abuse damages in 30 and 35% resp. liver functions. Therefore vitamin D deficiency develops. The authors recommend to follow up the health status of opiate abusers during oral substitution treatment (tertiary prevention).
Wilczek
H
H
III. Interní klinika 1. LF UK a VFN, Praha.
Presl
J
J
Douda
I
I
D000328:Adult; D005036:Ethylmorphine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009294:Narcotics / Q000627:therapeutic use*; D009293:Opioid-Related Disorders / Q000378:metabolism* / Q000534:rehabilitation*
D009294:Narcotics; D005036:Ethylmorphine