title: Effects of amphetamine on cell mediated immune response in mice.
abstract: Mice injected with amphetamine showed a dose-related suppression of the natural killer cell activity. The capacity of T-cells to generate cytotoxic T-lymphocytes (CTL) in mixed lymphocyte cultures and in vivo was also assayed and amphetamine was found to inhibit CTL responses.
authors.affiliation: Department of Pharmacology, University of Santiago de Compostela, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: Núñez-Iglesias
authors.forename: C
authors.initials: C
authors.lastname: Castro-Bolaño
authors.forename: C
authors.initials: C
authors.lastname: Losada
authors.forename: M D
authors.initials: MD
authors.lastname: Pereiro-Raposo
authors.forename: P
authors.initials: P
authors.lastname: Riveiro
authors.forename: P
authors.initials: P
authors.lastname: Sánchez-Sebio
authors.forename: J M
authors.initials: JM
authors.lastname: Mayán-Santos
authors.forename: M
authors.initials: M
authors.lastname: Rey-Méndez
authors.forename: M
authors.initials: M
authors.lastname: Freire-Garabal
mesh_terms: D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D007111:Immunity, Cellular / Q000187:drug effects*; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013154:Spleen / Q000166:cytology / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000187:drug effects / Q000276:immunology
chemical_list: D000661:Amphetamine