title: Cushing's disease due to a giant pituitary adenoma in early infancy: CT and MRI features.
abstract: We report the case of a 12-month-old girl presenting with diabetes insipidus and Cushing s disease. Brain magnetic resonance imaging (MRI) demonstrated a large tumour arising from the sella turcica, extending up to the foramen of Monro and invading the cavernous sinuses. Surgery was performed to remove the suprasellar part of the tumour, and histology revealed an adrenocorticotrophin (ACTH) secreting pituitary adenoma. This entity is very rare in this age group and the MRI features have not previously been described.
authors.affiliation: Department of Radiology, Centre Hospitalier Universitaire Vaudois, CH-1011 Lausanne, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Maeder
authors.forename: F
authors.initials: F
authors.lastname: Gudinchet
authors.forename: B
authors.initials: B
authors.lastname: Rillet
authors.forename: G
authors.initials: G
authors.lastname: Theintz
authors.forename: R
authors.initials: R
authors.lastname: Meuli
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D003480:Cushing Syndrome / Q000209:etiology*; D003919:Diabetes Insipidus / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed