Hormonal supplementation as treatment for cyclical rashes in patients with systemic lupus erythematosus.
Skin involvement is common in patients with SLE, and in some cases is related to the menstrual period. We describe the clinical course of 3 patients with menstrual related rashes who experienced a significant improvement from their skin disease after the initiation of oral contraceptives. The potential role of hormones in the manifestations of SLE is discussed.
Pando
J A
JA
National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
Gourley
M F
MF
Wilder
R L
RL
Crofford
L J
LJ
D000293:Adolescent; D002648:Child; D003276:Contraceptives, Oral / Q000627:therapeutic use*; D003872:Dermatitis / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D004338:Drug Combinations; D045166:Estradiol Congeners / Q000627:therapeutic use*; D004997:Ethinyl Estradiol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000503:physiopathology; D008597:Menstrual Cycle; D009644:Norgestrel / Q000627:therapeutic use
D003276:Contraceptives, Oral; D004338:Drug Combinations; D045166:Estradiol Congeners; D009644:Norgestrel; D004997:Ethinyl Estradiol