title: Single fiber electromyography in studies of neuromuscular function.
abstract: Single-fiber electromyography (SFEMG) allows precise study of the microphysiology of the human motor unit under normal conditions. The physiological parameters that can be quantified include impulse transmission along the intramuscular axon collaterals, pre- and post synaptic events at the neuromuscular junction, and muscle fiber membrane properties. This chapter illustrates some of the advantages of SFEMG in studies of neuromuscular fatigue in normal muscle, as well as in disorders of neuromuscular transmission, and conditions associated with disturbed muscle fiber depolarization-repolarization.
authors.affiliation: University Institute of Clinical Neurophysiology, University Medical Center of Ljubljana, Slovenia.
authors.forename: J V
authors.initials: JV
authors.lastname: Trontelj
authors.forename: E
authors.initials: E
authors.lastname: Stålberg
mesh_terms: D000818:Animals; D004576:Electromyography; D006801:Humans; D018485:Muscle Fibers, Skeletal / Q000502:physiology*; D009157:Myasthenia Gravis / Q000503:physiopathology; D009222:Myotonia / Q000503:physiopathology; D009469:Neuromuscular Junction / Q000503:physiopathology*