[Study of the relation between dose of ionizing radiation and level of chromosome abnormalities in an adult patient following total body irradiation].
The dose-effect relationship for dicentric chromosome aberrations and centric rings was studied in a female patient exposed to whole-body gamma irradiation for myeloid leukaemia. Samples were taken before and at different times during the exposure. The dose-effect relationship is on the linear-quadratic type and practically identical with those found earlier when the blood from adults and children was irradiated in vitro and only slightly above that of children irradiated in vivo.
Baltus
I
I
Unité de Tératogenèse et Mutagenèse, Université Catholique de Louvain, Bruxelles, Belgique.
Hung
T H
TH
Léonard
E D
ED
Gerber
G B
GB
Léonard
A
A
D000016:Abnormalities, Radiation-Induced / Q000453:epidemiology*; D000328:Adult; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000532:radiotherapy; D014916:Whole-Body Irradiation