title: Traumatic brain injury.
abstract: Traumatic brain injury (TBI) contributes significantly to the mortality and morbidity rates of traumatized patients. This article presents current concepts in the pathophysiology of TBI, including mechanisms of injury, biomolecular mediators of injury, and the occurrence of secondary injury. Emergency management, monitoring, and imaging of TBI also are reviewed.
authors.affiliation: Department of Surgery, Section of Emergency Medicine, University of Michigan Medical School, Ann Arbor, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Zink
mesh_terms: D000465:Algorithms; D001930:Brain Injuries / Q000145:classification / Q000503:physiopathology* / Q000628:therapy; D003131:Combined Modality Therapy; D003399:Craniotomy; D003422:Critical Care / Q000379:methods*; D003952:Diagnostic Imaging; D004359:Drug Therapy, Combination; D005440:Fluid Therapy; D006801:Humans; D007442:Intubation, Intratracheal; D008991:Monitoring, Physiologic / Q000379:methods