Cystic fibrosis. Gastrointestinal complications and gene therapy.
The gastrointestinal and nutritional complications of cystic fibrosis are diverse. As longevity improves in patients with cystic fibrosis, management of these complications is becoming increasingly important . This article provides overviews of the molecular aspects of the pathogenesis of cystic fibrosis, the current status of gene therapy, and a review of the gastrointestinal manifestations and nutritional care.
Shalon
L B
LB
Department of Pediatrics, Hasbro Children's Hospital, Brown University School of Medicine, Providence, Rhode Island, 02903, USA.
Adelson
J W
JW
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D005767:Gastrointestinal Diseases / Q000235:genetics*; D015316:Genetic Therapy / Q000379:methods; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010641:Phenotype