title: Case report: cystic fibrosis and embryonal carcinoma of the testis.
abstract: The authors describe a patient with cystic fibrosis and a stage III testicular embryonal cell cancer. Because cystic fibrosis occurs in approximately 1 of 2,500 births and embryonal carcinoma in 3 of 100,000, the likelihood of concurrence for both disorders in the same patient is approximately 1 in 80 million. Involvement of the vas deferens in cystic fibrosis raises the possibility of a fundamental embryologic basis that explains the pathogenesis of this association.
authors.affiliation: Center for Human Genetics, Boston University School of Medicine, Massachusetts, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Milunsky
authors.forename: A
authors.initials: A
authors.lastname: Milunsky
mesh_terms: D000328:Adult; D018236:Carcinoma, Embryonal / Q000150:complications* / Q000196:embryology / Q000473:pathology; D003550:Cystic Fibrosis / Q000150:complications* / Q000196:embryology; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D013736:Testicular Neoplasms / Q000150:complications* / Q000196:embryology / Q000473:pathology