Effect of ethanol on human erythrocyte superoxide dismutase activity and malonyl dialdehyde concentration.
The effect of a single administration of ethanol on the erythrocyte superoxide dismutase activity and malonyl dialdehyde concentration was examined in 14 healthy volunteers. We observed that 30 min after ethanol consumption in a dose 0.6 g/kg of body weight, superoxide dismutase activity was significantly higher as compared to that before ethanol treatment. No changes in susceptibility of erythrocytes to lipid peroxidation was observed after ethanol consumption. There was no significant changes in the malonyl dialdehyde concentration before and after ethanol treatment.
Dudek
I M
IM
Department of Medical Physiology, Military Medical Academy, Lodz, Poland.
Kedziora
J
J
Zagórski
T
T
D000328:Adult; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism*; D010084:Oxidation-Reduction; D013482:Superoxide Dismutase / Q000378:metabolism*
D000431:Ethanol; D008315:Malondialdehyde; D013482:Superoxide Dismutase