Interferon-alpha treatment for severe atopic dermatitis.
Patients with both severe atopic dermatitis (AD) and chronic myeloid leukemia, chronic hepatitis B, or chronic hepatitis C were treated with interferon-alpha (IFN-alpha). IFN-alpha treatment improved AD. Moreover, there were also significant decreases in serum IgE and IgG4 levels and in in vitro spontaneous IgE and IgG4 production by patients' mononuclear cells.
Kimata
H
H
Department of Pediatrics, Kyoto University Hospital, Japan.
Akiyama
Y
Y
Kubota
M
M
Furusho
K
K
D000293:Adolescent; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D002648:Child; D003876:Dermatitis, Atopic / Q000097:blood / Q000628:therapy*; D005260:Female; D006509:Hepatitis B / Q000628:therapy; D006526:Hepatitis C / Q000628:therapy; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male
D007074:Immunoglobulin G; D016898:Interferon-alpha; D007073:Immunoglobulin E; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase