[The time of severe acute ischemia as a risk factor in the restoration of the circulation in the ischemic extremity in embolisms of the major arteries].
It was found that clinical symptoms of the III degree ischemia were not reliable criteria of reversibility of ischemic disorders which requires additional information. The express-histochemical method of examination of bioptates of the ischemic extremity muscles is thought to be highly informative under such conditions as well as studying indices of the prekallikrein-kallikrein system of blood. The leading importance may be attached to the factor of time of severe ischemia when no additional information can be obtained. In patients with the III degree ischemia and its duration over 12 hours primary amputation of the extremity is indicated without an attempt being made to reestablish the blood flow.
Ivashchenko
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D000208:Acute Disease; D001157:Arterial Occlusive Diseases / Q000453:epidemiology / Q000473:pathology*; D001706:Biopsy; D002196:Capillaries / Q000648:ultrastructure; D004617:Embolism / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D007511:Ischemia / Q000453:epidemiology / Q000473:pathology*; D007866:Leg / Q000098:blood supply*; D008854:Microscopy, Electron; D009132:Muscles / Q000098:blood supply / Q000648:ultrastructure; D012307:Risk Factors; D013997:Time Factors