title: Pulp reaction to a dentin bonding agent.
abstract: OBJECTIVE
  To determine the pulpal biocompatibility of Prisma Universal Bond 2 (PUB-2).
  
  
  METHODS
  Class V preparations were made in eight subhuman monkeys to approximately 1 mm from the pulp. In Group 1, the enamel was etched, the primer was placed and dried, PUB 2 was painted, and Prisma-Fil inserted. In Goup 2, the cavity floor was covered with visible light-cured Dycal followed by the steps as in group 1. In Group 3, IRM was used as a negative control. In Group 4, MQ55 silicate cement was used as a positive control. The animals were sacrificed at 5, 25, and 60 days and the teeth processed for histological evaluation.
  
  
  RESULTS
  After 5 days, a mild reaction of little concern, which had dissipated in the 25- and 6-day groups, was observed. The material compared favorably to the negative control.
authors.affiliation: University of Connecticut, School of Dental Medicine, Department of Prosthodontics, Farmington, CT 06030, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Pameijer
authors.forename: H R
authors.initials: HR
authors.lastname: Stanley
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002126:Calcium Hydroxide / Q000633:toxicity; D003188:Composite Resins / Q000633:toxicity; D003736:Dental Cavity Lining; D003763:Dental Leakage; D003782:Dental Pulp / Q000187:drug effects*; D003786:Dental Pulp Cavity / Q000382:microbiology; D003809:Dentin, Secondary / Q000187:drug effects / Q000254:growth & development; D017220:Dentin-Bonding Agents / Q000633:toxicity*; D008252:Macaca fascicularis; D008689:Methacrylates / Q000633:toxicity; D008903:Minerals / Q000633:toxicity; D011140:Polyurethanes / Q000633:toxicity; D013997:Time Factors
chemical_list: D003188:Composite Resins; D017220:Dentin-Bonding Agents; D008689:Methacrylates; D008903:Minerals; D011140:Polyurethanes; C062652:Prisma Universal Bond; C029824:urethane dimethacrylate luting resin; C036885:prisma-fil; C025702:Dycal; D002126:Calcium Hydroxide