title: Activity of sucralfate (sucrose octa-sulphate), an anti-ulcer agent, against opportunistic gram-negative bacilli.
abstract: The in-vitro activity of sucralfate (sucrose octa-sulphate) in suspension was examined against 128 strains of Gram-negative bacilli. Inhibitory activity was demonstrated against all isolates and bactericidal activity was demonstrated for 68. Sucralfate has inhibitory and bactericidal antibacterial activity which may contribute to its in-vivo clinical efficacy.
authors.affiliation: Dulwich Public Health Laboratory, King's College School of Medicine and Dentistry, London, UK.
authors.forename: S G
authors.initials: SG
authors.lastname: Bragman
authors.forename: C L
authors.initials: CL
authors.lastname: Pankhurst
authors.forename: M W
authors.initials: MW
authors.lastname: Casewell
mesh_terms: D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009894:Opportunistic Infections / Q000382:microbiology*; D013392:Sucralfate / Q000494:pharmacology*
chemical_list: D000897:Anti-Ulcer Agents; D013392:Sucralfate