Effect of "core" 2'5'-oligoadenylates on the phosphorylation-dependent calcium channels in GH3 cells.
The effect of intracellular application of isolated and purified forms of "core" oligoadenylates (2',5',ApApA, 2',5'ApApepoxyA and 3',5'ApApA) on the phosphorylation-dependent calcium channels in GH3 cells was investigated. The role of Mg2+ ions in realizing of the processes of enhancement of phosphorylation-dependent calcium currents and prolongation of their wash-out during whole-cell patch-clamp experiments was examined.
Kostyuk
P G
PG
Kozlov
A V
AV
Tkachuk ZYu
Viatchenko-Karpinksi
S V
SV
Sedova
M V
MV
Mikhaikopulo
I A
IA
Kvasyuk
V I
VI
Tselenko
V I
VI
D000227:Adenine Nucleotides / Q000494:pharmacology*; D000818:Animals; D015220:Calcium Channels / Q000187:drug effects*; D015640:Ion Channel Gating / Q000187:drug effects*; D008274:Magnesium / Q000502:physiology*; D009843:Oligoribonucleotides / Q000494:pharmacology*; D018408:Patch-Clamp Techniques; D010766:Phosphorylation; D014407:Tumor Cells, Cultured
D000227:Adenine Nucleotides; D015220:Calcium Channels; D009843:Oligoribonucleotides; C023505:2',5'-oligoadenylate; D008274:Magnesium