title: Association of immune cells with neuroepithelial bodies in the lungs of neonatal dogs, cats and hamsters.
abstract: A close topographical association between neuroepithelial bodies and immune cells is occasionally observed in the lungs of various neonatal mammalian species. The immune cells concerned are mast cells and neutrophil or eosinophil granulocytes. In the lungs of newborn puppies having undergone left lung autotransplantation, mast cells are particularly numerous in the airway mucosa of both right and left lungs and their association with neuroepithelial bodies is highly significant. Several of the substances known to be synthesized by the neuroepithelial bodies have a chemoattractive effect on immune cells. Thus, our observations indicate that intrapulmonary neuroepithelial bodies contribute to the local immune response.
authors.affiliation: Katholieke Universiteit te Leuven, School of Medicine, Laboratory of Histopathology, 12 Minderbroedersstraat, B-3000 Leuven, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: van Lommel
authors.forename: P
authors.initials: P
authors.lastname: van den Steen
authors.forename: J M
authors.initials: JM
authors.lastname: Lauweryns
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002415:Cats; D006224:Cricetinae; D004285:Dogs; D004804:Eosinophils / Q000166:cytology; D007962:Leukocytes / Q000166:cytology*; D008168:Lung / Q000166:cytology* / Q000276:immunology; D009504:Neutrophils / Q000166:cytology