title: Concomitant cardiac and pulmonary operations for lung cancer.
abstract: From 1973 through 1990, 21 patients (17 men and 4 women) underwent concomitant cardiac operation and pulmonary resection for lung cancer. The mean age was 65.3 years (range, 50 to 80 years). Eighteen patients underwent coronary artery bypass; 1 underwent coronary bypass and mitral valve replacement; 1, aortic valve replacement; and 1, left ventricular aneurysmectomy. Pulmonary procedures included 16 lobectomies, 3 segmentectomies, and 2 wedge resections. Nine resections were performed during cardiopulmonary bypass, and 12 were performed either before or after bypass. On final pathologic diagnosis, 11 patients had adenocarcinoma, 7 had squamous cell carcinoma, and 3 had undifferentiated lesions. Twelve patients were in cancer stage 1 and 9 were in stage II. Placement of an intraaortic balloon pump was required in 3 patients. No patient sustained excessive blood loss requiring reoperation. Only 2 incidents (9.5%) of disseminated infection were reported. The overall 1-year survival rate was 90.5% and the 5-year survival rate was 52.4%. We found concomitant cardiac operation and pulmonary resection for lung cancer to be a safe and effective alternative to staged treatment in patients not requiring a pneumonectomy. Combined cardiac and pulmonary surgery spares the patient the risk and cost of a 2nd major surgical procedure without compromising long-term survival.
authors.affiliation: Department of Cardiovascular Research, Texas Heart Institute, Houston 77030, USA.
authors.forename: S
authors.initials: S
authors.lastname: La Francesca
authors.forename: O H
authors.initials: OH
authors.lastname: Frazier
authors.forename: B
authors.initials: B
authors.lastname: Radovancĕvić
authors.forename: L F
authors.initials: LF
authors.lastname: De Caro
authors.forename: G J
authors.initials: GJ
authors.lastname: Reul
authors.forename: D A
authors.initials: DA
authors.lastname: Cooley
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000601:surgery; D002315:Cardiopulmonary Bypass; D002318:Cardiovascular Diseases / Q000150:complications* / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D016019:Survival Analysis; D016896:Treatment Outcome