title: Long-term effects of otitis media with effusion: otomicroscopic findings.
abstract: A cohort of 946 children who were screened for otitis media with effusion (OME) by serial tympanometry from the age of 2 to 4 years was followed up by otomicroscopy at 7.5 to 8 years of age. At school age, signs of active middle ear disease were present in 2.2% of ears that had been free from OME at preschool age, whereas 12.7% of ears that had suffered from persistent OME and 17.8% of ears that had been treated by a ventilation tube showed signs of active middle ear disease. Otopathologic sequelae (atrophy, tympanosclerosis, atelectasis, and attic retraction) were present in 13.7%, 39.8%, and 87.3% of these ears, respectively. A duration-response effect was found in the association between preschool OME and these sequelae at school age. The high prevalence of otoscopic abnormalities found in this population calls for further follow-up and evaluation of their functional implications.
authors.affiliation: Department of Otorhinolaryngology, University of Nijmegen, The Netherlands.
authors.forename: A G
authors.initials: AG
authors.lastname: Schilder
authors.forename: G A
authors.initials: GA
authors.lastname: Zielhuis
authors.forename: M P
authors.initials: MP
authors.lastname: Haggard
authors.forename: P
authors.initials: P
authors.lastname: van den Broek
mesh_terms: D000158:Acoustic Impedance Tests / Q000379:methods; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009426:Netherlands; D010034:Otitis Media with Effusion / Q000503:physiopathology* / Q000628:therapy; D011379:Prognosis