title: A human case of invasive fascioliasis associated with liver abscess.
abstract: A 56 year-old Korean housewife/farmer/goat keeper suffered from right upper quadrant pain and fever with chills. In the abdominal sonogram and computerized tomography, multiple, 2-3 cm, irregular shaped cavities were observed in the right lobe of liver. A liver biopsy revealed extensive central necrosis with Characot-Leyden crystals surrounded by palisading histiocytes, eosinophil-rich inflammatory infiltration. Worm was not observed. However, the serologic test for Fasciola-specific IgG antibody by micro-ELISA was positive. Prior antibody levels did not differ and eosinophilia persisted 6 and 16 months after praziquantel treatment although the cavitary lesions in the liver disappeared 6 months after the treatment. Reported herein is a human case of invasive fascioliasis diagnosed clinically by a combination of radiological, histopathological and serological studies.
authors.affiliation: Department of Internal of Medicine, College of Medicine, Hallym University, Chunchon, Korea.
authors.forename: J B
authors.initials: JB
authors.lastname: Kim
authors.forename: D J
authors.initials: DJ
authors.lastname: Kim
authors.forename: S
authors.initials: S
authors.lastname: Huh
authors.forename: S Y
authors.initials: SY
authors.lastname: Cho
mesh_terms: D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis; D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use; D004797:Enzyme-Linked Immunosorbent Assay; D005211:Fascioliasis / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008100:Liver Abscess / Q000150:complications*; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use; D012698:Serologic Tests
chemical_list: D000909:Antibodies, Helminth; D000980:Antiplatyhelmintic Agents; D007074:Immunoglobulin G; D011223:Praziquantel