title: Corneal scarring after photorefractive keratectomy in a penetrating keratoplasty.
abstract: OBJECTIVE
  To report severe scarring in a corneal graft after excimer laser photorefractive keratectomy.
  
  
  METHODS
  A 35-year-old man underwent photorefractive keratectomy twice for severe compound myopic astigmatism and anisometropia after penetrating keratoplasty.
  
  
  RESULTS
  Corneal opacity corresponded to areas of irregular epithelial thickness, focal absence of the basement membrane, loss of Bowman's layer, and stromal scarring in the ablation zone.
  
  
  CONCLUSIONS
  There may be an increased risk of severe corneal stromal scarring from photorefractive keratectomy in eyes that have had previous penetrating keratoplasty.
authors.affiliation: Department of Ophthalmology, Jules Stein Eye Institute, UCLA School of Medicine, CA 90095-7003, USA.
authors.forename: W K
authors.initials: WK
authors.lastname: Chan
authors.forename: K E
authors.initials: KE
authors.lastname: Hunt
authors.forename: B J
authors.initials: BJ
authors.lastname: Glasgow
authors.forename: B J
authors.initials: BJ
authors.lastname: Mondino
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000209:etiology / Q000601:surgery; D002921:Cicatrix / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003318:Corneal Opacity / Q000209:etiology / Q000473:pathology; D006801:Humans; D007640:Keratoconus / Q000601:surgery; D015948:Keratoplasty, Penetrating / Q000009:adverse effects; D054018:Lasers, Excimer; D008297:Male; D009216:Myopia / Q000209:etiology / Q000601:surgery; D018903:Photorefractive Keratectomy / Q000009:adverse effects*; D011183:Postoperative Complications; D012086:Reoperation