title: Cranial nerve preservation after stereotactic radiosurgery of intracanalicular acoustic tumors.
abstract: We reviewed our initial stereotactic radiosurgery experience in 10 patients with intracanalicular acoustic tumors managed by radiosurgery during a 5-year period. These patients constitute 4.7% of acoustic tumor patients who underwent Gamma Knife radiosurgery during this period. Tumor volume stabilization was achieved in 8. Two patients had initial growth followed by delayed growth arrest. Preservation of preoperative hearing was achieved in all patients in the immediate postoperative period and in 8 of 10 at 1 year. No patient had developed facial or trigeminal nerve dysfunction at the last follow-up, which varied from 3 to 64 months (mean 25 months). Tumor growth was delayed in 2 patients, but neither has required delayed microsurgical resection. All patients returned to their preoperative functional status within 3-5 days after radiosurgery. Stereotactic radiosurgery using the Gamma Knife is a safe and effective management strategy for intracanalicular acoustic tumor patients. Our initial results indicate that high cranial nerve preservation rates and a rapid return to previous activity and employment are benefits of radiosurgery.
authors.affiliation: Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pa., USA.
authors.forename: O K
authors.initials: OK
authors.lastname: Ogunrinde
authors.forename: D L
authors.initials: DL
authors.lastname: Lunsford
authors.forename: D S
authors.initials: DS
authors.lastname: Kondziolka
authors.forename: D J
authors.initials: DJ
authors.lastname: Bissonette
authors.forename: J C
authors.initials: JC
authors.lastname: Flickinger
mesh_terms: D000328:Adult; D000368:Aged; D001299:Audiometry; D005154:Facial Nerve / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007759:Labyrinth Diseases / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000601:surgery*; D011183:Postoperative Complications; D016634:Radiosurgery; D012665:Semicircular Canals / Q000601:surgery*; D016896:Treatment Outcome; D014725:Vestibular Nerve / Q000502:physiology