title: [Interferon-associated retinopathy].
abstract: BACKGROUND
  Recently interferons have been utilized for hepatitis C or some other tumorous conditions. However, a new interferon-associated retinopathy has been reported. There are to our knowledge, no publications in German-speaking countries.
  
  
  METHODS
  Four patients developed after interferon therapy cotton-wool spots combined with splinter hemorrhage.
  
  
  RESULTS
  The retinopathy occurred 5-30 days after the beginning of the therapy. In one case the retinopathy aggravated following dose elevation, whereas in two other cases the cotton-wool spots and hemorrhages disappeared irrespective of continued interferon therapy.
  
  
  CONCLUSIONS
  Interferons cannot be primarily responsible for the development of retinopathy.
authors.affiliation: Augenklinik Fujita Health University Toyoake.
authors.forename: T
authors.initials: T
authors.lastname: Hararda
authors.forename: H
authors.initials: H
authors.lastname: Fukami
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
authors.forename: T
authors.initials: T
authors.lastname: Niwa
authors.forename: Y
authors.initials: Y
authors.lastname: Majima
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000628:therapy; D005260:Female; D005451:Fluorescein Angiography; D006526:Hepatitis C / Q000628:therapy; D006801:Humans; D007372:Interferons / Q000009:adverse effects* / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012164:Retinal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012166:Retinal Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis; D012307:Risk Factors
chemical_list: D007372:Interferons