Diagnostic and genetic issues of depression and bipolar illness.
Depression and bipolar illness are the major affective disorders. Various genetic studies indicate the existence of inherited susceptibility factors. Recent linkage studies indicate that loci on chromosomes 18, 21, and X contribute to genetic susceptibility of bipolar illness.
Berrettini
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Department of Psychiatry, Thomas Jefferson University, Philadelphia, PA 19107, USA.
D001714:Bipolar Disorder / Q000175:diagnosis / Q000235:genetics*; D002887:Chromosomes, Human, Pair 18 / Q000235:genetics; D002891:Chromosomes, Human, Pair 21 / Q000235:genetics; D003863:Depression / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D014960:X Chromosome / Q000235:genetics