beta-Endorphin and blood pressure in multiple trauma victims.
In addition to pain and stress, endogenous opiates and in particular beta-endorphin could be involved in the modulation of cardiovascular parameters. Several studies have thus shown increases in plasma beta-endorphin levels in the course of septic or hypovolemic shock. Our study involving 44 multiple trauma patients indicates that even in the absence of any hemodynamic disorders, there is a correlation between systolic blood pressure and plasma beta-endorphins. These results argue in favor of the existence of feedback between systolic blood pressure and plasma beta-endorphins.
Guieu
R
R
Laboratoire de Biochimie, Faculté de Médecine Secteur Nord, URA CNRS 1455, Marseille France.
Paganelli
F
F
Martin
C
C
Albanese
J
J
Juin
M A
MA
Rochat
H
H
Bechis
G
G
Devaux
C
C
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000097:blood / Q000503:physiopathology*; D011863:Radioimmunoassay; D001615:beta-Endorphin / Q000097:blood*
D001615:beta-Endorphin