title: Congenital bilateral perisylvian syndrome in a monozygotic twin with intra-uterine death of the co-twin.
abstract: Congenital bilateral perisylvian syndrome was diagnosed in a two-year- old boy with signs of pseudobulbar and diplegic cerebral palsy presenting on MRI a polymicrogyric appearance of the perisylvian regions. He was born from a monochorionic bi-amniotic twin pregnancy complicated by twin-twin transfusion syndrome and death of the co-twin between the 16th and 18th weeks of gestation. Ventricular enlargement and hepatic hyperechogenic lesions were seen during his sonographic intra-uterine follow-up. The authors suggest that ischaemic injury occurred in this patient as a consequence of acute haemodynamic changes induced by the death of his co-twin.
authors.affiliation: Department of Neurology (Pediatric Neurology), Hopital Erasme, Universite Libre de Bruxelles, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Van Bogaert
authors.forename: C
authors.initials: C
authors.lastname: Donner
authors.forename: P
authors.initials: P
authors.lastname: David
authors.forename: F
authors.initials: F
authors.lastname: Rodesch
authors.forename: E F
authors.initials: EF
authors.lastname: Avni
authors.forename: H B
authors.initials: HB
authors.lastname: Szliwowski
mesh_terms: D002535:Cerebral Aqueduct / Q000002:abnormalities*; D002547:Cerebral Palsy / Q000151:congenital / Q000175:diagnosis*; D002675:Child, Preschool; D005260:Female; D005313:Fetal Death / Q000150:complications*; D005330:Fetofetal Transfusion / Q000150:complications*; D006801:Humans; D008297:Male; D010243:Paralysis / Q000151:congenital / Q000175:diagnosis*; D011247:Pregnancy; D013577:Syndrome; D014430:Twins, Monozygotic