MR imaging in solvent-induced chronic toxic encephalopathy.
OBJECTIVE
To use MR to examine patients with CNS symptoms indicating +chronic intoxication.


METHODS
Thirty-two subjects exposed to industrial solvents for 5 to 28 years and 40 age-matched, healthy controls were examined.


RESULTS
All patients showed decreased signal in the basal ganglia on T2-weighted images. In 11 of the patients the white matter showed diffuse hyperintensity with loss of the grey-white matter discrimination and with distinct periventricular hyperintensities in 5 of the patients. The controls had no pathological changes in the brain.


CONCLUSIONS
Although the relatively small number of patients may obscure the significance, findings observed on T2-weighted images were patchy periventricular hyperintensities and hypointensities in the basal ganglia. Fast spin-echo is a good technique with fast acquisition of images with true spin-echo contrast features.
Thuomas
K A
KA
Department of Diagnostic Radiology, University Hospital, Linköping, Sweden.
Möller
C
C
Odkvist
L M
LM
Flodin
U
U
Dige
N
N
D000328:Adult; D001479:Basal Ganglia / Q000473:pathology; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis*; D016273:Occupational Exposure; D011041:Poisoning / Q000175:diagnosis; D012997:Solvents / Q000633:toxicity*
D012997:Solvents