title: Regional assignment of 30 expressed sequence tags on human chromosome 7 using a somatic cell hybrid panel.
abstract: The regional assignments of 30 expressed sequence tags (ESTs) on human chromosome 7 were determined by studying the segregation of their PCR-amplified products in a panel of mouse somatic cell hybrids. ESTs are important molecular landmarks for physical mapping and can be considered as tags to candidate genes for genetically linked human inherited diseases. These results contribute further potential gene sequences to the transcriptional map of chromosome 7.
authors.affiliation: Department of Molecular Genetics, Institute of Ophthalmology, London, United Kingdom.
authors.forename: R J
authors.initials: RJ
authors.lastname: Patel
authors.forename: T J
authors.initials: TJ
authors.lastname: Keen
authors.forename: K H
authors.initials: KH
authors.lastname: Grzeschik
authors.forename: W C
authors.initials: WC
authors.lastname: Nierman
authors.forename: P
authors.initials: P
authors.lastname: Hayes
authors.forename: S S
authors.initials: SS
authors.lastname: Bhattacharya
authors.forename: C F
authors.initials: CF
authors.lastname: Inglehearn
mesh_terms: D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping / Q000379:methods*; D002897:Chromosomes, Human, Pair 7; D003398:Craniosynostoses / Q000235:genetics; D017868:Cyclic AMP-Dependent Protein Kinases / Q000235:genetics; D016208:Databases, Factual; D030342:Genetic Diseases, Inborn / Q000235:genetics; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000235:genetics; D016133:Polymerase Chain Reaction; D012174:Retinitis Pigmentosa / Q000235:genetics; D016324:Sequence Tagged Sites
chemical_list: D009419:Nerve Tissue Proteins; C075637:amphiphysin; D017868:Cyclic AMP-Dependent Protein Kinases