Malignant Brenner tumor of the ovary: two cases of unusual histologic features of relapsed tumors.
This study focused on unusual histologic features observed in 2 relapsed Brenner tumors. Case 1: A 67-year-old woman had a malignant Brenner tumor. The tumor relapsed was squamous-cell carcinoma. Case 2: A 51-year-old woman had a proliferating and malignant Brenner tumor with mucinous metaplasia. The relapsed tumor was a well-differentiated mucinous adenocarcinoma. These cases suggest that: (1) the relapsed tumor cells survived chemotherapy; and (2) the relapsed tumor cells transformed.
Kataoka
A
A
Department of Obstetrics and Gynecology, Kurume University, School of Medicine, Fukuoka, Japan.
Nishida
T
T
Imaishi
K
K
Sugiyama
T
T
Yakushiji
M
M
D000230:Adenocarcinoma / Q000473:pathology; D000236:Adenoma / Q000473:pathology; D001948:Brenner Tumor / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*