Impaired brainstem auditory evoked potentials in patients with cystic fibrosis.
Brainstem auditory evoked potentials (BAEPs) were measured in 11 young patients with cystic fibrosis (CF). Though none had clinical evidence of neurological impairment, all had various abnormal components of brainstem auditory evoked potentials (BAEPs). Abnormal BAEPs may be attributed to nutritional deficiencies including deficiencies of vitamins E and B6. As patients with CF are often deficient in vitamin E despite daily supplementation and normal serum levels, the authors suggest that the abnormal BAEPs demonstrated in the present study may reflect prolonged intracellular vitamin E deficiency. This finding suggests that BAEP studies may be useful in the neurological evaluation of patients with CF.
Vaisman
N
N
Paediatrics Department, Kaplan Hospital Rehovot, Israel.
Tabachnik
E
E
Shahar
E
E
Gilai
A
A
D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications* / Q000503:physiopathology*; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D026681:Vitamin B 6 Deficiency / Q000209:etiology; D014811:Vitamin E Deficiency / Q000097:blood / Q000209:etiology*