title: [Synchronous manifestation of bladder inverted papilloma and transitional carcinoma of the renal pelvis].
abstract: OBJECTIVE
  To review briefly the histological and biological aspects of inverted papilloma and to determine whether it is a benign tumor or low-grade malignant lesion.
  
  
  RESULTS
  We report a patient with synchronous presentation of bladder inverted papilloma and renal pelvis transitional cell carcinoma. After endoscopic resection of the bladder tumor and left ureteral meatus, a radical nephroureterectomy was carried out with success. The clinical features, diagnostic and therapeutic aspects are briefly reviewed.
  
  
  CONCLUSIONS
  Inverted papilloma accounts for 2.2% of all urothelial tumors; the bladder is most commonly involved. It is frequently a single lesion with endophytic growth pattern. The clinical significance remains a controversy. Most investigators consider them as benign neoplastic tumors, although in one third of the patients it may be associated with synchronous urothelial carcinomas, implying a malignant condition. Therapeutic management and follow-up are emphasized.
authors.affiliation: Servicio de Urología y Departamento de Anatomía Patológica, Hospital de Galdakao, Vizcaya, España.
authors.forename: J G
authors.initials: JG
authors.lastname: Pereira Arias
authors.forename: I
authors.initials: I
authors.lastname: Zabalza Estévez
authors.forename: M
authors.initials: M
authors.lastname: Maraña Fernández
authors.forename: V
authors.initials: V
authors.lastname: Escobal Tamayo
authors.forename: A J
authors.initials: AJ
authors.lastname: Catalina
authors.forename: J L
authors.initials: JL
authors.lastname: Paz Romeral
authors.forename: J G
authors.initials: JG
authors.lastname: Ibarluzea González
authors.forename: C
authors.initials: C
authors.lastname: Bernuy Malfaz
mesh_terms: D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis; D007682:Kidney Pelvis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D018308:Papilloma, Inverted / Q000175:diagnosis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis