Modern management of dyspepsia.
Dyspepsia affects one in four Australians; of those who present in general practice, the majority will have functional or non-ulcer dyspepsia, with no structural explanation for their symptoms. Older patients who present for the first time with dyspepsia, and those with 'alarm features' deserve immediate investigation (preferably by upper endoscopy), to exclude cancer, peptic ulcer or oesophagitis. Other patients may be given empiric therapy (for example, a prokinetic or H2 blocker) initially, but require investigation if this fails. The role of Helicobacter pylori infection in functional dyspepsia is uncertain.
Talley
N J
NJ
Nepean Hospital, University of Sydney.
D000328:Adult; D000368:Aged; D000863:Antacids / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001729:Bismuth / Q000627:therapeutic use; D002648:Child; D002769:Cholelithiasis / Q000150:complications / Q000175:diagnosis; D002908:Chronic Disease; D020117:Cisapride; D003937:Diagnosis, Differential; D004294:Domperidone / Q000627:therapeutic use; D018492:Dopamine Antagonists / Q000627:therapeutic use; D004415:Dyspepsia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D016480:Helicobacter pylori; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use; D010437:Peptic Ulcer / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D010880:Piperidines / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000150:complications / Q000175:diagnosis
D000863:Antacids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000897:Anti-Ulcer Agents; D018492:Dopamine Antagonists; D006635:Histamine H2 Antagonists; D010880:Piperidines; D004294:Domperidone; D008787:Metoclopramide; D001729:Bismuth; D020117:Cisapride