title: Autosomal dominant holocalvarial craniosynostosis.
abstract: Isolated holocalvarial synostosis with normal intelligence is described in two pairs of sibs from one kindred. Diagnosis was delayed until the age of 5 years in the pro-band. The gene carriers were asymptomatic and had no head deformity. The genetic pattern is consistent with autosomal dominant inheritance.
authors.affiliation: Department of Human Genetics, Rambam Medical Center, Haifa, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Pillar
authors.forename: M
authors.initials: M
authors.lastname: Zaaroor
authors.forename: R
authors.initials: R
authors.lastname: Gershoni-Baruch
mesh_terms: D017668:Age of Onset; D002648:Child; D003398:Craniosynostoses / Q000235:genetics* / Q000601:surgery; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007360:Intelligence / Q000235:genetics; D008297:Male; D010375:Pedigree