Cytogenetic abnormalities in 13 patients with multiple myeloma.
Cytogenetic analysis was successfully performed in 45 consecutive multiple myeloma (MM) patients. Cytogenetic abnormalities were observed in 13 of 45 patients (29%). Eleven patients showed numerical changes and 9 showed structural abnormalities in chromosomes 5, 9, 11, 14, 15, and 19 were most frequently gained. Structural abnormalities preferentially involved chromosomes 6, 13, and 14.
Solé
F
F
Laboratori de Citologia Hematològica, Unitat d'Hematologia i Oncologia1973, Hospital Central L'Aliança, Barcelona, Spain.
Woessner
S
S
Acín
P
P
Pérez-Losada
A
A
Florensa
L
L
Besses
C
C
Sans-Sabrafen
J
J
D000368:Aged; D000369:Aged, 80 and over; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000235:genetics*