title: Direct measurement of reactivity in the protein crystal by steady-state kinetic studies.
authors.affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Stoddard
authors.forename: G K
authors.initials: GK
authors.lastname: Farber
mesh_terms: D002918:Chymotrypsin / Q000737:chemistry; D018360:Crystallography, X-Ray / Q000295:instrumentation / Q000379:methods*; D005615:Freezing; D007521:Isocitrate Dehydrogenase / Q000737:chemistry; D007700:Kinetics; D008958:Models, Molecular; D055585:Physical Phenomena; D010825:Physics; D011485:Protein Binding; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D011506:Proteins; D007521:Isocitrate Dehydrogenase; D002918:Chymotrypsin