Vitamin E in intestinal fat malabsorption.
This study was done on 5 patients suffering from tropical sprue (8-10 years' duration). Serum vitamin E level was significantly low in these patients. Cell-mediated immune mechanism assessed by using 2,4-dinitrochlorobenzene, a skin-sensitizing hapten, was also depressed. Polyneuropathy was also observed. Repletion of vitamin deficiency was associated with marked improvement in T-cell functions and neuropathy.
Ghalaut
V S
VS
Department of Biochemistry and Medicine, Pt. Bhagwat Dayal Sharma Post-Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
Ghalaut
P S
PS
Kharb
S
S
Singh
G P
GP
D000328:Adult; D004137:Dinitrochlorobenzene; D006801:Humans; D007111:Immunity, Cellular; D008875:Middle Aged; D009422:Nervous System Diseases / Q000188:drug therapy; D012882:Skin Tests; D013182:Sprue, Tropical / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D014810:Vitamin E / Q000008:administration & dosage / Q000627:therapeutic use*; D014811:Vitamin E Deficiency / Q000150:complications* / Q000276:immunology
D004137:Dinitrochlorobenzene; D014810:Vitamin E