title: The nuclear-encoded 18 kDa (IP) AQDQ subunit of bovine heart complex I is phosphorylated by the mitochondrial cAMP-dependent protein kinase.
abstract: In bovine heart mitochondria a protein of M(r) 18 kDa, phosphorylated by mtPKA, is associated to the NADH-ubiquinone oxidoreductase in the inner membrane and is present in purified preparation of this complex. The 18 kDa phosphoprotein has now been isolated and sequenced. It is identified as the 18 kDa (IP) AQDQ subunit of complex I, a protein of 133 amino acids with a phosphorylation consensus site RVS at position 129-131.
authors.affiliation: Institute of Medical Biochemistry and Chemistry, CNR, University of Bari, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Papa
authors.forename: A M
authors.initials: AM
authors.lastname: Sardanelli
authors.forename: T
authors.initials: T
authors.lastname: Cocco
authors.forename: F
authors.initials: F
authors.lastname: Speranza
authors.forename: S C
authors.initials: SC
authors.lastname: Scacco
authors.forename: Z
authors.initials: Z
authors.lastname: Technikova-Dobrova
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D017868:Cyclic AMP-Dependent Protein Kinases / Q000378:metabolism*; D042967:Electron Transport Complex I; D008929:Mitochondria, Heart / Q000201:enzymology*; D008969:Molecular Sequence Data; D009247:NADH, NADPH Oxidoreductases / Q000235:genetics* / Q000378:metabolism; D010766:Phosphorylation; D016415:Sequence Alignment
chemical_list: D009247:NADH, NADPH Oxidoreductases; D017868:Cyclic AMP-Dependent Protein Kinases; D042967:Electron Transport Complex I