title: IgA deficiency and psoriasis: relevance of IgA in the pathogenesis of psoriasis.
abstract: A psoriatic patient with absolute deficiency of IgA is reported. The manifestations of psoriasis appeared at the age of 6 months and proved to be resistant to various treatments. The present case report and the data available in the literature on IgA and psoriasis all converge on the hypothesis that IgA is a systemic factor which belongs to the 'off switches' of the psoriatic process.
authors.affiliation: Department of Dermatology, University Hospital Nijmegen, The Netherlands.
authors.forename: P C
authors.initials: PC
authors.lastname: van de Kerkhof
authors.forename: P M
authors.initials: PM
authors.lastname: Steijlen
mesh_terms: D000328:Adult; D004351:Drug Resistance; D006801:Humans; D017098:IgA Deficiency / Q000150:complications*; D007070:Immunoglobulin A / Q000032:analysis / Q000276:immunology*; D007223:Infant; D008297:Male; D011565:Psoriasis / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology
chemical_list: D007070:Immunoglobulin A