HIV treatment choice based on resistance patterns.
Patterns of resistance and cross-resistance to the available antiretroviral agents are increasingly well documented. Interactions between different mutations, both synergistic and antagonistic, may be used to design optimum combination regimens and therapy sequences, as well as to construct decision-making algorithms.
Moyle
G
G
Chelsea and Westminster Hospital, London, UK.
D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial / Q000235:genetics; D015751:Genes, pol / Q000235:genetics; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology; D015497:HIV-1 / Q000187:drug effects* / Q000235:genetics; D006801:Humans; D009154:Mutation
D000998:Antiviral Agents