title: [3 different malignancies of the aerodigestive tract after chronic abuse of cannabis products].
abstract: The occurrence of multilocular malignant tumors in the upper aerodigestive tract in young patients with known marijuana abuse has been described by other authors. A case of a 28-year-old man who was known to abuse alcohol, nicotine and cannabis for some years is presented. He suffered simultaneously from a squamous cell carcinoma of the hypopharynx with bilateral cervical metastases, an adenocarcinoma of the transverse colon and a primary hepatocellular carcinoma. This case is the first reported that shows the occurrence of three separate malignant tumors with different histologies in the aerodigestive tract which could be related to a chronic abuse of cannabis.
authors.affiliation: HNO-Klinik, Universitätsklinik Freiburg.
authors.forename: B
authors.initials: B
authors.lastname: Richter
authors.forename: N
authors.initials: N
authors.lastname: Marangos
authors.forename: A
authors.initials: A
authors.lastname: Jeron
authors.forename: S
authors.initials: S
authors.lastname: Irscheid
mesh_terms: D000230:Adenocarcinoma / Q000139:chemically induced* / Q000473:pathology; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects; D002186:Cannabinoids / Q000009:adverse effects*; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced* / Q000473:pathology; D003043:Cocarcinogenesis; D003110:Colonic Neoplasms / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008297:Male; D002189:Marijuana Abuse / Q000150:complications* / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced* / Q000473:pathology; D012907:Smoking / Q000009:adverse effects
chemical_list: D002186:Cannabinoids