title: Atypical cutaneous histological features of visceral leishmaniasis in acquired immunodeficiency syndrome.
abstract: Cutaneous lesions in Mediterranean visceral leishmaniasis (VL) are very unusual, except for the presence of Leishmania organisms in cutaneous Kaposi's sarcoma in patients with acquired immunodeficiency syndrome (AIDS). We have identified two unusual cutaneous histological features of VL in three patients with AIDS not described previously; two had "silent leishmaniasis," and in the third, Leishmania organisms were present in sweat ducts, suggesting transepithelial elimination through eccrine sweat glands and/or eccrine epithelial tropism.
authors.affiliation: Department of Pathology, University of Nice, France.
authors.forename: C
authors.initials: C
authors.lastname: Perrin
authors.forename: B
authors.initials: B
authors.lastname: Taillan
authors.forename: P
authors.initials: P
authors.lastname: Hofman
authors.forename: V
authors.initials: V
authors.lastname: Mondain
authors.forename: Y
authors.initials: Y
authors.lastname: Lefichoux
authors.forename: J F
authors.initials: JF
authors.lastname: Michiels
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000469:parasitology*; D000328:Adult; D000818:Animals; D004439:Eccrine Glands / Q000469:parasitology; D005260:Female; D006679:HIV Seropositivity / Q000469:parasitology; D006644:Histiocytes / Q000469:parasitology; D006801:Humans; D018314:Leishmania infantum / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000473:pathology*; D008297:Male; D012514:Sarcoma, Kaposi / Q000469:parasitology*; D012867:Skin / Q000469:parasitology* / Q000473:pathology; D012878:Skin Neoplasms / Q000469:parasitology*; D013545:Sweat Glands / Q000469:parasitology