title: Merkel cell carcinoma of the eyelid.
abstract: OBJECTIVE
  To demonstrate the clinical variability and histologic characteristics of Merkel cell carcinoma of the eyelid.
  
  
  METHODS
  We investigated two cases of Merkel cell carcinoma of the eyelid in a 67-year-old man and an 83-year-old woman, respectively. Both lesions were initially misdiagnosed as benign tumors on clinical examination.
  
  
  RESULTS
  After the correct diagnosis was made, both lesions were treated with wide resection aided by frozen sections, and reconstructive surgery.
  
  
  CONCLUSIONS
  Merkel cell carcinoma is an aggressive tumor with variable clinical manifestation. Radical surgical therapy and close follow-up are indicated.
authors.affiliation: Departments of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.
authors.forename: J B
authors.initials: JB
authors.lastname: Soltau
authors.forename: M E
authors.initials: ME
authors.lastname: Smith
authors.forename: P L
authors.initials: PL
authors.lastname: Custer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015266:Carcinoma, Merkel Cell / Q000201:enzymology / Q000473:pathology* / Q000601:surgery; D005142:Eyelid Neoplasms / Q000201:enzymology / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D012878:Skin Neoplasms / Q000201:enzymology / Q000473:pathology* / Q000601:surgery
chemical_list: D010751:Phosphopyruvate Hydratase