title: Detection by Western blot of four antigens characterizing acute clinical leishmaniasis due to Leishmania infantum.
abstract: Western blot analysis of sera from 32 patients with acute clinical leishmaniasis due to Leishmania infantum showed the simultaneous presence of antibodies against 4 antigens with molecular masses of 18, 21, 23, 31 kDa. The simultaneous presence of these 4 antigens was specific to the clinical disease and it was not detected in 47 sera from asymptomatic individuals living in the leishmaniasis endemic area of Alpes-Maritimes (southern France) or in 37 sera from patients with other protozoan infections.
authors.affiliation: Groupe de Recherche en Immunopathologie de la Leishmaniose, Faculté de Médecine, Université de Nice-Sophia Antipolis, France.
authors.forename: P
authors.initials: P
authors.lastname: Marty
authors.forename: A
authors.initials: A
authors.lastname: Lelièvre
authors.forename: J F
authors.initials: JF
authors.lastname: Quaranta
authors.forename: I
authors.initials: I
authors.lastname: Suffia
authors.forename: M
authors.initials: M
authors.lastname: Eulalio
authors.forename: M
authors.initials: M
authors.lastname: Gari-Toussaint
authors.forename: Y
authors.initials: Y
authors.lastname: Le Fichoux
authors.forename: J
authors.initials: J
authors.lastname: Kubar
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000953:Antigens, Protozoan / Q000097:blood* / Q000737:chemistry; D015153:Blotting, Western; D005260:Female; D006801:Humans; D018314:Leishmania infantum / Q000276:immunology*; D016773:Leishmaniasis, Cutaneous / Q000276:immunology*; D007898:Leishmaniasis, Visceral / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight
chemical_list: D000953:Antigens, Protozoan