title: Microscopic polyangiitis with ocular involvement.
abstract: Microscopic polyangiitis is an exclusively small-vessel (arterioles, capillaries, or venules) vasculitis that primarily involves the kidney and often involves the lungs, skin, or nervous system. Characteristic features include focal segmental glomerulonephritis, nongranulomatous necrotizing vasculitis, and serum positive for perinuclear-staining antineutrophil cytoplasmic antibodies (P-ANCA). We report a case of microscopic polyangiitis with previously unreported eyelid and conjunctival manifestations that responded well to immunosuppressive therapy.
authors.affiliation: Department of Ophthalmology, University of Texas Houston Health Science Center, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Caster
authors.forename: D J
authors.initials: DJ
authors.lastname: Shetlar
authors.forename: M A
authors.initials: MA
authors.lastname: Pappolla
authors.forename: R W
authors.initials: RW
authors.lastname: Yee
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003228:Conjunctiva / Q000098:blood supply / Q000473:pathology; D003229:Conjunctival Diseases / Q000188:drug therapy / Q000473:pathology*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005141:Eyelid Diseases / Q000188:drug therapy / Q000473:pathology*; D005143:Eyelids / Q000098:blood supply / Q000473:pathology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology*; D014657:Vasculitis / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone