title: Disseminated cytomegalovirus infection in an immunocompetent adult successfully treated with ganciclovir.
abstract: We report the case of a previously healthy man who suffered a disseminated cytomegalovirus infection. He presented with prolonged fever, weight loss of 8 kg, anicteric hepatitis, upper digestive tract bleeding from gastric ulcers, acute polyneuritis and bilateral retinitis. Immunodeficiency was not detected either during admission or during a 3-year follow-up period. The patient was treated with ganciclovir (5 mg/kg BID) during 4 weeks with a favourable clinical outcome. To our knowledge, this is the first reported case with such characteristics.
authors.affiliation: Department of Internal Medicine, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: López-Contreras
authors.forename: J
authors.initials: J
authors.lastname: Ris
authors.forename: P
authors.initials: P
authors.lastname: Domingo
authors.forename: M
authors.initials: M
authors.lastname: Puig
authors.forename: N
authors.initials: N
authors.lastname: Rabella
authors.forename: J
authors.initials: J
authors.lastname: Nolla
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D017726:Cytomegalovirus Retinitis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D015774:Ganciclovir / Q000627:therapeutic use*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir