title: Crossed quadrant homonymous hemianopsia in a case of multiple sclerosis.
abstract: We describe the first report of crossed quadrant hemianopsia (CQHH) occurring in a patient with a well documented clinical history of Multiple Sclerosis (MS). The visual field studied by a Humphrey Field Analyzer (Mod.630, 30-2 program) showed a CQHH, involving right superior quadrants and left inferior ones. Magnetic resonance imaging (MRI) showed two lesions located in both left and right trigone area, corresponding to the geniculocalcarine pathways. CQHH is a very rare visual field defect commonly caused by vertebro-basilar ischemia and attributed to bilateral injury of the calcarine fissure. In the absence of lesions in the primary visual cortex, a direct relationship between the quadrantonopic defect and two small demyelinating lesions in posterior periventricular white matter, corresponding to the geniculocalcarine pathways, is implied.
authors.affiliation: Institute of Ophthalmology, University of Rome, La Sapienza, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Cesareo
authors.forename: C
authors.initials: C
authors.lastname: Pozzilli
authors.forename: G
authors.initials: G
authors.lastname: Ristori
authors.forename: A M
authors.initials: AM
authors.lastname: Roscioni
authors.forename: A
authors.initials: A
authors.lastname: Missiroli
mesh_terms: D000328:Adult; D001921:Brain / Q000503:physiopathology; D001330:Electronic Data Processing; D006423:Hemianopsia / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology