title: Sweet syndrome associated with G-CSF treatment in a child with glycogen storage disease type Ib.
abstract: Acute febrile neutrophilic dermatosis (Sweet syndrome) is rare in children and is regularly associated with underlying malignancies or inflammtory diseases. A 5-year-old girl with glycogen storage disease type Ib, neutropenia, and recurrent infections developed characteristic skin eruption of Sweet syndrome after 2 years of granulocyte colony-stimulating factor (G-CSF) therapy. This association points to a possible role of G-CSF-induced granulopoiesis and granulodyte activation in the pathogenesis of Sweet syndrome.
authors.forename: B Z
authors.initials: BZ
authors.lastname: Garty
authors.forename: I
authors.initials: I
authors.lastname: Levy
authors.forename: M
authors.initials: M
authors.lastname: Nitzan
authors.forename: Y
authors.initials: Y
authors.lastname: Barak
mesh_terms: D001706:Biopsy; D002675:Child, Preschool; D005260:Female; D005953:Glycogen Storage Disease Type I / Q000628:therapy*; D016179:Granulocyte Colony-Stimulating Factor / Q000009:adverse effects*; D006801:Humans; D016463:Sweet Syndrome / Q000139:chemically induced* / Q000473:pathology
chemical_list: D016179:Granulocyte Colony-Stimulating Factor