[Progress in the study of cyclic nucleotide phosphodiesterases].
There are five families of cyclic nucleotide phosphodiesterase isozymes, which have a common structure, but have different biochemical characteristics, physiologic functions and regulatory mechanisms. Various selective phosphodiesterase inhibitors may have potential uses for antiasthmatic, inotropic, vasodilative, antithrombotic and antidepressant drugs.
Zhou
H L
HL
Division of Antiasthmatic Drug Research, Zhejiang Medical University, Hangzhou.
Bian
R L
RL
D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases / Q000737:chemistry / Q000502:physiology*; D000818:Animals; D000242:Cyclic AMP / Q000502:physiology; D006152:Cyclic GMP / Q000502:physiology; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000502:physiology*
D007527:Isoenzymes; D000242:Cyclic AMP; D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases; D006152:Cyclic GMP