[Genetic analysis of Vibrio cholerae chromosomal regions containing the tox-2 mutation, affecting production of cholera toxin].
Conjugational-mating experiments showed mrh genes coding for the synthesis of mannose and fucose resistant hemagglutinin/adhesin and vibrio motility gene mot to be localized in the chromosome of V. cholerae Dacca strain 35 close to tox-2 mutation providing a high level of toxin production and rfb locus which controls 01 antigen synthesis. The results indicate the presence of a block of virulence genes within ura-pur chromosomal region of V. cholerae.
Smirnova
N I
NI
Davydova
N I
NI
Eroshenko
G A
GA
D001426:Bacterial Proteins / Q000235:genetics*; D002772:Cholera Toxin / Q000096:biosynthesis*; D002876:Chromosomes, Bacterial; D003227:Conjugation, Genetic; D005643:Fucose / Q000096:biosynthesis; D008358:Mannose / Q000096:biosynthesis; D009154:Mutation; D014734:Vibrio cholerae / Q000235:genetics* / Q000378:metabolism / Q000472:pathogenicity; D014774:Virulence / Q000235:genetics
D001426:Bacterial Proteins; D005643:Fucose; D002772:Cholera Toxin; D008358:Mannose