title: [Treatment of severe neutropenias in dogs and cats with filgrastim].
abstract: The recombinant hG-CSF Filgrastim was used in severe cases of neutropenia in the dog caused by parvovirosis, hyperestrogenism, treatment with antineoplastic agents, an aplastic syndrome and in the cat in cases of infectious panleukopenia. Increases of the numbers of leukocytes were observed in all groups of diseases in the dog, but not in feline infectious panleukopenia. Filgrastim is indicated in neutropenias associated with disturbance of the general condition accompanied by fever, but not in cases of transitory leukopenias.
authors.affiliation: I. Medizinischen Tierklinik, Lehrstuhl für Innere Krankheiten des Pferdes.
authors.forename: W
authors.initials: W
authors.lastname: Kraft
authors.forename: M
authors.initials: M
authors.lastname: Kuffer
mesh_terms: D000741:Anemia, Aplastic / Q000188:drug therapy / Q000662:veterinary; D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects; D002371:Cat Diseases; D002415:Cats; D004283:Dog Diseases; D004285:Dogs; D004967:Estrogens / Q000502:physiology; D000069585:Filgrastim; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D007970:Leukopenia / Q000097:blood / Q000188:drug therapy / Q000662:veterinary; D009503:Neutropenia / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D010322:Parvoviridae Infections / Q000097:blood / Q000662:veterinary; D011994:Recombinant Proteins / Q000627:therapeutic use; D013045:Species Specificity; D013577:Syndrome
chemical_list: D000970:Antineoplastic Agents; D004967:Estrogens; D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor; D000069585:Filgrastim