The effects of albuterol and isokinetic exercise on the quadriceps muscle group.
Subjects performed 9 wk of isokinetic knee extensions twice weekly. Albuterol (N = 13) or placebo (N = 9) was administered for 6 wk; groups received 16 mg.d-1 of either treatment. Training consisted of three sets of 10 repetitions at 45 degrees.s-1. Data were collected at weeks 0, 6, and 9. Concentric and eccentric variables examined included: peak torque (CPT, EPT), total work (CTW, ETW), average power (CAP, EAP), time to peak torque (CTTPT, ETTPT), peak torque to body weight ratio (CPT/BW), and work to body weight ratio (CW/BW, EW/BW). Other variables included: thigh circumference (CIRC), thigh cross-sectional area (CSA), forced vital capacity (FVC), and forced expiratory volume (FEV1), MANOVA and the Dunn-Bonferroni post-hoc found differences within groups for CPT, CTW, CAP, CPR/BW, EPT, ETTPT, and CSA. Interactions were noted for CW/BW, ETW, EAP, EPT/BW, and ETW/BW; with persons administered albuterol yielding superior values. CW/BW, ETW, and EAP showed interactions at post-testing, while EPT/BW and EW/BW interacted at both midtesting and post-testing. Results indicate therapeutic doses of albuterol administered with resistance exercise may augment strength gains.
Caruso
J F
JF
Human Performance Laboratory, University of Miami, Coral Gables, FL 33124, USA.
Signorile
J F
JF
Perry
A C
AC
Leblanc
B
B
Williams
R
R
Clark
M
M
Bamman
M M
MM
D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D000328:Adult; D000420:Albuterol / Q000494:pharmacology*; D015444:Exercise; D006801:Humans; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000502:physiology*
D000318:Adrenergic beta-Agonists; D000420:Albuterol