Leiomyomatosis peritonealis disseminata: clinicopathologic analysis of five cases.
Leiomyomatosis peritonealis disseminata (LPD) is an exceedingly rare, usually benign condition that clinically simulates a disseminated malignancy. It occurs predominantly in women of childbearing age. Approximately 50 cases of LPD have been described in the literature with 2 cases reported to have progressed into aggressive leiomyosarcomas. Excessive hormonal stimulation appears to correlate with LPD development since it is commonly associated with pregnancy. Conservative treatment with long-term follow-up is recommended because of LPD's generally indolent clinical course. We report 5 cases of LPD with a review of the literature.
Hardman
W J
WJ
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30341, USA.
Majmudar
B
B
D000328:Adult; D003276:Contraceptives, Oral; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D018231:Leiomyomatosis / Q000473:pathology*; D007890:Leiomyosarcoma / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*
D003276:Contraceptives, Oral