Pregnancy complications and birth outcomes in obese and normal-weight women: effects of gestational weight change.
OBJECTIVE
To compare the pregnancy course and outcomes in obese and normal-weight women and their associations with gestational weight change.


METHODS
Multivariate logistic regression described the relation of weight change to pregnancy course and outcomes in a retrospective study of 683 obese and 660 normal-weight women who delivered singleton living neonates.


RESULTS
Compared with normal-weight women, obese women gained an average of 5 kg (11 lb) less during pregnancy and were more likely to lose or gain no weight (11% versus less than 1%). Obese women were significantly more likely to have pregnancy complications, but the incidence of complications was not associated with weight change. Compared with obese women who gained 7-11.5 kg (15-25 lb), obese women who lost or gained no weight were at higher risk for delivery of infants under 3000 g or small for gestational age infants, and those who gained more than 16 kg (35 lb) were at twice the risk for delivery of infants who were 4000 g or heavier.


CONCLUSIONS
Gestational weight change was not associated with pregnancy complications in obese or normal-weight women. To optimize fetal growth, weight gains of 7-11.5 kg (15-25 lb) for obese women and 11.5-16 kg (25-35 lb) for normal-weight women appear to be appropriate.
Edwards
L E
LE
Department of Obstetrics and Gynecology, St. Paul-Ramsey Medical Center, St. Paul, MN, USA.
Hellerstedt
W L
WL
Alton
I R
IR
Story
M
M
Himes
J H
JH
D001724:Birth Weight; D005260:Female; D005865:Gestational Age; D006801:Humans; D009765:Obesity / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011256:Pregnancy Outcome; D012044:Regression Analysis; D012189:Retrospective Studies; D015430:Weight Gain