title: Which blood gas caused the brain damage?
abstract: In order to analyse the effects of various physiological parameters including blood gas data on the cerebral oxygenation, we developed a model to enable us to estimate PtO2 (tissue PO2) from these physiological parameters. This model was applied successfully to a set of blood gas data of a patient who had brain damage after cardiac surgery. Contrary to the original impression, we concluded that a very low PaCO2 of 13 mmHg towards the end of CPB was the most likely cause of his damage.
authors.affiliation: Department of Anaesthesia, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Suwa
mesh_terms: D001831:Body Temperature; D001921:Brain / Q000378:metabolism*; D001925:Brain Damage, Chronic / Q000209:etiology*; D002245:Carbon Dioxide / Q000097:blood*; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D002560:Cerebrovascular Circulation; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D016857:Hypocapnia / Q000097:blood / Q000150:complications; D000860:Hypoxia / Q000097:blood / Q000150:complications; D002534:Hypoxia, Brain / Q000097:blood / Q000150:complications; D007223:Infant; D008297:Male; D008954:Models, Biological; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption; D012984:Software
chemical_list: D006454:Hemoglobins; D002245:Carbon Dioxide; D010100:Oxygen