Choroidal hemorrhage associated with systemic tissue plasminogen activator.
OBJECTIVE
To determine the cause of spontaneous choroidal hemorrhage in a 67-year-old man after a myocardial infarction and administration of tissue plasminogen activator.


METHODS
The patient underwent ocular examination.


RESULTS
The patient retained excellent visual acuity and the choroidal hemorrhage resolved completely within two months.


CONCLUSIONS
The administration of tissue plasminogen activator was responsible for the large extent of hemorrhage and should be considered in the differential diagnosis of hemorrhagic choroidal detachment.
Khawly
J A
JA
Department of Ophthalmology, Duke University Eye Center, NC 27710, USA.
Ferrone
P J
PJ
Holck
D E
DE
D000368:Aged; D002829:Choroid / Q000000981:diagnostic imaging; D015862:Choroid Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging; D002832:Choroid Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy; D010960:Plasminogen Activators / Q000009:adverse effects* / Q000627:therapeutic use; D010959:Tissue Plasminogen Activator / Q000009:adverse effects* / Q000627:therapeutic use; D014463:Ultrasonography; D014792:Visual Acuity
D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator