Genetic pre-disposition to colorectal cancer: Initiation of a prospective study in Eastern Ontario.
A pilot study which is part of both a larger provincial initiative and a network is in progress to address the question of genetic pre-disposition to non-polyposis colorectal cancer in eastern Ontario (population 1,200,000). It is modeled along a dual process of recruitment of at-risk individuals based on either prior documentation of family histories or a close relationship to patients who are hospitalized for colorectal cancer treatment. The molecular diagnostic and genetic counseling components of the project are in their initial phase of operation while follow-up strategies are being planned.
Lagarde
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Loeb Medical Research Institute, Ottawa Civic Hospital, Canada.
Stern
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HS
D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D004198:Disease Susceptibility; D005192:Family Health; D006801:Humans; D009864:Ontario / Q000453:epidemiology; D010865:Pilot Projects; D011446:Prospective Studies; D012307:Risk Factors