title: The Landau-Kleffner Syndrome: a review.
abstract: The Landau-Kleffner syndrome or the syndrome of acquired epileptic aphasia was first described in 1957. The disorder is characterised by gradual or rapid loss of language in a previously normal child. All children have abnormal EEG compatible with the diagnosis of epilepsy, however, only 70% have clinical seizures. The present article presents a review of the current knowledge concerning this disorder. Information is provided related to the clinical picture, etiology, pathogenesis, treatment and outcome.
authors.affiliation: Department of Child Psychiatry, Bispebjerg Hospital, Copenhagen, Denmark.
authors.forename: S E
authors.initials: SE
authors.lastname: Mouridsen
mesh_terms: D017668:Age of Onset; D001921:Brain / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D018887:Landau-Kleffner Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D007806:Language Disorders / Q000628:therapy; D013070:Speech Therapy