title: Cytogenetic abnormalities in 13 patients with multiple myeloma.
abstract: Cytogenetic analysis was successfully performed in 45 consecutive multiple myeloma (MM) patients. Cytogenetic abnormalities were observed in 13 of 45 patients (29%). Eleven patients showed numerical changes and 9 showed structural abnormalities in chromosomes 5, 9, 11, 14, 15, and 19 were most frequently gained. Structural abnormalities preferentially involved chromosomes 6, 13, and 14.
authors.affiliation: Laboratori de Citologia Hematològica, Unitat d'Hematologia i Oncologia1973, Hospital Central L'Aliança, Barcelona, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Solé
authors.forename: S
authors.initials: S
authors.lastname: Woessner
authors.forename: P
authors.initials: P
authors.lastname: Acín
authors.forename: A
authors.initials: A
authors.lastname: Pérez-Losada
authors.forename: L
authors.initials: L
authors.lastname: Florensa
authors.forename: C
authors.initials: C
authors.lastname: Besses
authors.forename: J
authors.initials: J
authors.lastname: Sans-Sabrafen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000235:genetics*