title: Absorbable devices in the fixation of fractures.
abstract: Totally absorbable internal fracture fixation devices were introduced clinically in the treatment of fractures and osteotomies of the extremities at our department in 1984. A total of 2,500 patients were managed using bone or ligament fixation devices made of self-reinforced (matrix and fibers of same polymer) absorbable alpha-hydroxy polyesters between November 5, 1984, and January 12, 1994. The devices used included cylindrical rods or pins, screws, tacks, plugs, and wires. The most common indication for the use of absorbable implants was displaced malleolar fracture of the ankle. Transphyseal fixation with small-diameter polyglycolide pins was used in children. The postoperative clinical course was uneventful in over 90% of the patients. The complications included bacterial wound infection in 3.6% and failure of fixation in 3.7%. In one-fifth of these cases, however, reoperation was not necessary. The occurrence of noninfectious foreign-body reactions 2 to 3 months postoperatively has been observed in 2.3% of the patients operated in the last years with polyglcolide implants but in none of the patients with polylactide implants. This inflammatory tissue response often required aspiration with a needle or small incision but did not influence the ultimate functional or radiologic result of treatment. Owing to the biodegradability of these internal fixation devices, over 1,000 implant removal procedures were avoided during the 9-year period under review, allowing medical personnel at these facilities to focus on other procedures. Avoidance of removal procedures results in financial benefits and psychological advantages. The benefits of absorbable implants for war surgery are the same as for civilian life. Absorbable implants can also be used in open fractures and infection operations.
authors.affiliation: Department of Orthopaedics and Traumatology, Helsinki University, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Rokkanen
authors.forename: O
authors.initials: O
authors.lastname: Böstman
authors.forename: S
authors.initials: S
authors.lastname: Vainionpää
authors.forename: E A
authors.initials: EA
authors.lastname: Makela
authors.forename: E
authors.initials: E
authors.lastname: Hirvensalo
authors.forename: E K
authors.initials: EK
authors.lastname: Partio
authors.forename: K
authors.initials: K
authors.lastname: Vihtonen
authors.forename: H
authors.initials: H
authors.lastname: Pätiälä
authors.forename: P
authors.initials: P
authors.lastname: Törmälä
mesh_terms: D000042:Absorption; D000328:Adult; D000818:Animals; D001673:Biodegradation, Environmental; D002648:Child; D005593:Fracture Fixation, Internal / Q000295:instrumentation*; D006801:Humans; D009984:Orthopedic Fixation Devices; D011091:Polyesters; D011100:Polyglycolic Acid; D011183:Postoperative Complications; D011817:Rabbits; D012086:Reoperation
chemical_list: D011091:Polyesters; D011100:Polyglycolic Acid; C033616:poly(lactide)