title: Cardiac output measurement in critically ill patients: comparison of continuous and conventional thermodilution techniques.
abstract: The purpose of the study was to compare cardiac output (CO) measurement by continuous (CTD) with that by conventional thermodilution (TD) in critically ill patients. In 19 of 20 critically ill patients requiring a pulmonary artery catheterism, 105 paired CO measurements were performed by both CTD and TD. Regression analysis showed that: CTD CO = 1.18 TD CO - 0.47. Correlation coefficient was 0.96. Bias and limit of agreement were -0.8 and 2.4 L.min-1, respectively. When a Bland and Altman diagram was constructed according to cardiac index ranges, biases were -0.2 and -0.3 and -0.8 L.min-1.m-2 and limits of agreement were 0.3, 0.7 and 1.6 L.min-1.m-2 for low (< 2.5 L.min-1.m-2), normal (between 2.5 and 4.5 L.min-1.m-2) and high (> 4.5 L.min-1.m-2) cardiac indexes, respectively. It is concluded that CTD, compared with TD, is a reliable method of measuring CO, especially when cardiac index is < or = 4.5 L.min-1.m-2.
authors.affiliation: Département d'Anesthésie-Réanimation et de l'Urgence, CHU Nîmes, France.
authors.forename: J Y
authors.initials: JY
authors.lastname: Lefrant
authors.forename: P
authors.initials: P
authors.lastname: Bruelle
authors.forename: J
authors.initials: J
authors.lastname: Ripart
authors.forename: F
authors.initials: F
authors.lastname: Ibanez
authors.forename: G
authors.initials: G
authors.lastname: Aya
authors.forename: P
authors.initials: P
authors.lastname: Peray
authors.forename: G
authors.initials: G
authors.lastname: Saïssi
authors.forename: J E
authors.initials: JE
authors.lastname: de La Coussaye
authors.forename: J J
authors.initials: JJ
authors.lastname: Eledjam
mesh_terms: D015982:Bias; D002302:Cardiac Output; D002407:Catheterization, Swan-Ganz; D003080:Cold Temperature; D003422:Critical Care; D016638:Critical Illness; D005260:Female; D006801:Humans; D007267:Injections; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D012044:Regression Analysis; D015203:Reproducibility of Results; D012128:Respiratory Distress Syndrome / Q000503:physiopathology; D012769:Shock / Q000503:physiopathology; D012772:Shock, Septic / Q000503:physiopathology; D012965:Sodium Chloride / Q000008:administration & dosage; D013815:Thermodilution / Q000379:methods*
chemical_list: D012965:Sodium Chloride