title: An autosomal recessive nonsyndromic form of sensorineural hearing loss maps to 3p-DFNB6.
abstract: Autosomal recessive nonsyndromic hearing loss (ARNSHL) is the most common form of congenitally acquired inherited hearing impairment. Although numerous loci are believed to exist, only five have been identified. Using a pooled genomic DNA screening strategy, we have identified a sixth locus, DFNB6, on 3p in the interval bounded by D3S1619 and D3S1766.
authors.affiliation: Department of Otolaryngology, University of Iowa, Iowa City 52242, USA.
authors.forename: K
authors.initials: K
authors.lastname: Fukushima
authors.forename: A
authors.initials: A
authors.lastname: Ramesh
authors.forename: C R
authors.initials: CR
authors.lastname: Srisailapathy
authors.forename: L
authors.initials: L
authors.lastname: Ni
authors.forename: S
authors.initials: S
authors.lastname: Wayne
authors.forename: M E
authors.initials: ME
authors.lastname: O'Neill
authors.forename: G
authors.initials: G
authors.lastname: Van Camp
authors.forename: P
authors.initials: P
authors.lastname: Coucke
authors.forename: P
authors.initials: P
authors.lastname: Jain
authors.forename: E R
authors.initials: ER
authors.lastname: Wilcox
authors.forename: S D
authors.initials: SD
authors.lastname: Smith
authors.forename: J B
authors.initials: JB
authors.lastname: Kenyon
authors.forename: R I
authors.initials: RI
authors.lastname: Zbar
authors.forename: R J
authors.initials: RJ
authors.lastname: Smith
mesh_terms: D000483:Alleles; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3 / Q000235:genetics*; D003241:Consanguinity; D005260:Female; D005808:Genes, Recessive; D006319:Hearing Loss, Sensorineural / Q000235:genetics*; D006801:Humans; D008126:Lod Score; D008297:Male