[Effect of 1,25-dihydroxyvitamin D3 on 15-lipoxygenase activity].
The influence of 1.25-dihydroxyvitamin D3 on soybean 15-lipoxygenase activity was studied in vitro. 1.25-Dihydroxyvitamin D3 inhibited enzymatic activity in relation to its dose, pH and substrate (linoleic acid) concentration; the findings are indicative of a mixed type of inhibition.
Bondarenko
L B
LB
Kharchenko
O V
OV
Butovich
I A
IA
D002117:Calcitriol / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006863:Hydrogen-Ion Concentration; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000378:metabolism; D016859:Lipoxygenase Inhibitors; D013025:Glycine max / Q000201:enzymology; D013379:Substrate Specificity
D008041:Linoleic Acids; D016859:Lipoxygenase Inhibitors; D019787:Linoleic Acid; D002117:Calcitriol