title: Single point mutation at Arg506 of factor V associated with APC resistance and venous thromboembolism: improved detection by PCR-mediated site-directed mutagenesis.
authors.forename: J P
authors.initials: JP
authors.lastname: Rabès
authors.forename: M
authors.initials: M
authors.lastname: Trossaert
authors.forename: J
authors.initials: J
authors.lastname: Conard
authors.forename: M
authors.initials: M
authors.lastname: Samama
authors.forename: P
authors.initials: P
authors.lastname: Giraudet
authors.forename: C
authors.initials: C
authors.lastname: Boileau
mesh_terms: D001483:Base Sequence; D004351:Drug Resistance; D005165:Factor V / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D017354:Point Mutation; D016133:Polymerase Chain Reaction / Q000379:methods; D011486:Protein C / Q000627:therapeutic use*; D013923:Thromboembolism / Q000097:blood / Q000188:drug therapy / Q000235:genetics*; D014680:Veins / Q000378:metabolism / Q000473:pathology
chemical_list: D011486:Protein C; D005165:Factor V