Cutaneous sarcoid granulomas with oat cell carcinoma of the lung.
A case of a 68-year-old male is presented, with a history of asymptomatic slight scaling, infiltrated patches with an atrophic central portion, of 3 months of evolution on the face and trunk. A chest X-ray showed an oat cell lung carcinoma, with the same evolution time as the cutaneous lesions. Several cutaneous biopsies showed typical sarcoid granulomas, with profuse giant cells. An immunohistochemical study showed B-cell-positive granulomas. The patient was treated with cytostatic drugs and prednisone, leading to cutaneous, radiological and clinical complete regression of the lesions. We think that this case corresponds to a tumor-related cutaneous sarcoid granuloma reaction.
Conejo-Mir
J S
JS
Dermatology Department, Virgen del Rocio University Hospital, Seville, Spain.
Casals
M
M
Garciandia
C
C
Artola
J L
JL
Quintana del Olmo
J
J
Rivera Hueto
F
F
Navarrete
M
M
D000368:Aged; D001402:B-Lymphocytes / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000150:complications / Q000473:pathology*; D017809:Fatal Outcome; D015726:Giant Cells / Q000473:pathology; D006099:Granuloma / Q000150:complications / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D010257:Paraneoplastic Syndromes / Q000473:pathology; D012074:Remission Induction; D012871:Skin Diseases / Q000150:complications / Q000473:pathology*