title: Focal nodular hyperplasia of the liver in children: review of follow-up and outcome.
abstract: The authors used a conservative approach to treat focal nodular hyperplasia of the liver (FNH) and were interested in the long-term results of different therapeutic approaches in order to establish the most appropriate treatment. A review of the literature was conducted, and 31 pediatric case reports were identified in which follow-up and outcome data were noted. Tumor resection was performed in 18 cases (58%), operative biopsy alone in nine (29%), vascular ligation in two, and embolization of hepatic arteries in two. The outcome appears to be good for both groups of patients, ie, those with observation alone and those with resection. More information is to be collected regarding the new procedures (embolization and ligation). This is a retrospective analysis, and data from future international prospective studies are needed.
authors.affiliation: Department of Pediatrics, University Hospitals, Bern, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Reymond
authors.forename: J
authors.initials: J
authors.lastname: Plaschkes
authors.forename: A R
authors.initials: AR
authors.lastname: Lüthy
authors.forename: K
authors.initials: K
authors.lastname: Leibundgut
authors.forename: A
authors.initials: A
authors.lastname: Hirt
authors.forename: H P
authors.initials: HP
authors.lastname: Wagner
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D007223:Infant; D008099:Liver / Q000473:pathology*; D008297:Male; D017678:Sex Distribution; D016896:Treatment Outcome