title: Distribution of glucocorticoid receptor mRNA in the rat spinal cord.
abstract: Using in situ hybridization (ISH), we studied the distribution of rat glucocorticoid receptors (GR) mRNA in rat spinal cord. mRNA encoding for GR was abundant throughout the white matter and a clear pattern of distribution was detected within the grey matter. In the grey matter mRNA was primarily localized in the ventral horn, where motoneurones were strongly labelled. In the dorsal horn, the distribution appears more diffuse but the superficial layers (I and II) clearly exhibited a shigher signal. We conclude that, in rat spinal cord, GR are present in both glial and neuronal cells. In particular, both somatosensory and motor pathways contain GR.
authors.affiliation: Department of Internal Medicine, University of Rome, Tor Vergata, Italy.
authors.forename: L N
authors.initials: LN
authors.lastname: Marlier
authors.forename: T
authors.initials: T
authors.lastname: Csikós
authors.forename: N
authors.initials: N
authors.lastname: Rebaudengo
authors.forename: P
authors.initials: P
authors.lastname: Borboni
authors.forename: F R
authors.initials: FR
authors.lastname: Patacchioli
authors.forename: L
authors.initials: L
authors.lastname: Angelucci
authors.forename: A
authors.initials: A
authors.lastname: Privat
authors.forename: R
authors.initials: R
authors.lastname: Lauro
mesh_terms: D000818:Animals; D001483:Base Sequence; D008297:Male; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D011965:Receptors, Glucocorticoid / Q000235:genetics*; D013116:Spinal Cord / Q000737:chemistry*
chemical_list: D012333:RNA, Messenger; D011965:Receptors, Glucocorticoid