Some new 3-methoxy-5-methyl-1,4-substituted pyrazoles.
A series of 3-methoxypyrazole derivatives was synthesized and tested as antifungal agents. The substituents were chosen on the base of their lipophylicity and for their presence in well-known antifungal drugs. The compounds displayed no significant activity in vitro.
Garuti
L
L
Dipartimento di Scienze Farmaceutiche, Università di Bologna, Italy.
Roberti
M
M
Rossi
M
M
Giovanninetti
G
G
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002855:Chromatography, Thin Layer; D005658:Fungi / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents