[Study of radiation-induced change in the membrane structure using a fluorescent probe].
The effect of radiation on erythrocyte membrane structure has been investigated using fluorescent probe 4-(n-dimethyl aminostyryl)-1-methylpyridinium n-toluolsulfonate. The form of fluorescence spectra was analyzed and inhomogeneous broadening parameters of spectral components were estimated. It was shown that in erythrocyte membrane there were three types of DSM binding sites. The physico-chemical properties of DSM surrounding and probes distribution were found to change after irradiation.
Gorbenko
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GP
Diubko
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D000818:Animals; D001665:Binding Sites; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004910:Erythrocyte Membrane / Q000528:radiation effects*; D005456:Fluorescent Dyes; D011726:Pyridinium Compounds; D051381:Rats; D013050:Spectrometry, Fluorescence
C032315:4-(4-dimethylaminostyryl)-1-methylpyridinium; D005456:Fluorescent Dyes; D011726:Pyridinium Compounds