title: Electron transfer and proton pumping in cytochrome oxidase.
abstract: This article presents an outlook on the structure and function of terminal oxidases, the respiratory enzymes which catalyze the reduction of dioxygen to water in aerobic organisms. The structure of the redox active metals, their interactions with the protein matrix, and their role in electron transfer ligand binding and proton pumping are briefly reviewed.
authors.affiliation: Department of Biochemical Sciences, University of Rome La Sapienza, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Brunori
authors.forename: M T
authors.initials: MT
authors.lastname: Wilson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D004579:Electron Transport; D003576:Electron Transport Complex IV / Q000737:chemistry* / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology*; D008969:Molecular Sequence Data; D010084:Oxidation-Reduction; D017494:Proton Pumps; D017382:Reactive Oxygen Species / Q000737:chemistry
chemical_list: D017494:Proton Pumps; D017382:Reactive Oxygen Species; D003576:Electron Transport Complex IV