[Anti-MI-2 antibody as a specific marker of dermatomyositis].
Anti-Mi-2 antibody directed against the protein complex of unknown function is considered an immunological marker of dermatomyositis. We detected this antibody in 7 among 72 patients, whose sera were investigated for the presence of myositis specific autoantibodies with the use of indirect immunofluorescence and double immunodiffusion. Six patients had dermatomyositis, and 1 had unclassified collagenosis. Detection of anti-Mi-2 antibody is very important for diagnosis because of its high specificity, and also for prognosis and therapy.
Kowalska-Oledzka
E
E
Zespołu Badawczo-Leczniczego Chorób Nerwowo-Mieśniowych, Instytutu Centrum Medycyny Doświadczalnej i Klinicznej PAN.
Jarzabek-Chorzelska
M
M
Kołacińska-Strasz
Z
Z
D000328:Adult; D017668:Age of Onset; D001323:Autoantibodies / Q000276:immunology*; D002648:Child; D003882:Dermatomyositis / Q000276:immunology*; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D005779:Immunodiffusion; D008297:Male; D008875:Middle Aged
D001323:Autoantibodies