[Prognostic value of K-ras gene mutation in colorectal cancer].
Numerous acquired genetical mutations are now well described by molecular biology and seem to be related to tumour progression. K-RAS mutation is of interest in colorectal cancer where it could be correlated to an aggressive tumoral behaviour leading to a high risk of recurrence or metastasis.
Cerottini
J P
JP
Centre Hospitalier Universitaire Vaudois, Service de Chirurgie, Lausanne.
Givel
J C
JC
Benhattar
J
J
D002471:Cell Transformation, Neoplastic / Q000235:genetics* / Q000473:pathology; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology; D004252:DNA Mutational Analysis; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000235:genetics* / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics*
C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras)