title: Organism reaction to cryodestruction of the prostatic gland in dogs.
abstract: The aim of the investigation was to determine the effect of cryodestruction of the healthy prostate on general condition of dogs. The research was performed on 18 dogs divided into two groups: control and experimental. In the dogs from the experimental group after the laparotomy procedure the prostate was frozen in the repeated cycle using the flat cryoapplicator. The observations were carried out for 6 months. General condition of dogs was controlled, blood was examined and urine analysed. The performed determinations included the activity of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, acid phosphatase and prostatic isoenzyme of acid phosphatase. It has been observed that the cryodestruction procedures of the prostatic gland are well tolerated by dogs. During 3 weeks after the surgery the number of leucocytes in blood increased. An increased drop of the blood cells was observed for 2 weeks after the procedure. Characteristic behaviour was observed in case of the prostatic isoenzyme of acid phosphatase. Immediately after the procedure the increased activity of that enzyme was observed and 24h later its decrease which remained for about 2 weeks. Then the isoenzyme activity increased again and that increase lasted for the period of 2 months.
authors.affiliation: Department of Animal Surgery, Faculty of Veterinary Medicine, Warsaw Agricultural University, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Galanty
mesh_terms: D000135:Acid Phosphatase / Q000032:analysis; D000410:Alanine Transaminase / Q000032:analysis; D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D001219:Aspartate Aminotransferases / Q000032:analysis; D001799:Blood Sedimentation; D003452:Cryosurgery / Q000009:adverse effects / Q000592:standards / Q000662:veterinary*; D004285:Dogs / Q000097:blood / Q000601:surgery*; D007527:Isoenzymes / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D008297:Male; D011467:Prostate / Q000201:enzymology / Q000601:surgery*; D013997:Time Factors
chemical_list: D007527:Isoenzymes; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase