Novel sites of action for deprenyl in MPTP-parkinsonism: metabolite-mediated protection against striatal neurotoxicity and suppression of MPTP-induced increase of dopamine turnover in C57BL mice.
Sziráki
I
I
Institute for Drug Research, Budapest, Hungary.
Kardos
V
V
Patthy
M
M
Gaál
J
J
Arányi
P
P
Kollár
E
E
Tömösközi
Z
Z
Király
I
I
D000818:Animals; D003342:Corpus Striatum / Q000187:drug effects* / Q000378:metabolism; D004195:Disease Models, Animal; D004298:Dopamine / Q000378:metabolism*; D020267:MPTP Poisoning; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D010300:Parkinson Disease / Q000378:metabolism*; D010302:Parkinson Disease, Secondary / Q000209:etiology; D012642:Selegiline / Q000494:pharmacology*; D013997:Time Factors
D012642:Selegiline; D004298:Dopamine