[The diagnosis and prevention of hemostatic system disorders in the surgical treatment of patients with cancer of the large intestine].
The hemostasis system was studied before, during, and after surgery in 40 patients with colonic cancer administered no pretreatment and in 30 ones administered depogen before the operation and its combination with heparin after surgery. Preoperative depogen had a positive impact on both the coagulation and platelet components of the hemostasis. Depogen in complex with heparin reduced the intensity of subacute chronic intravascular blood coagulation during and after the operation and was conducive to a decrease of the incidence of postoperative complications in patients with colonic cancer.
Elizarova
A L
AL
Madzhuga
A V
AV
Somonova
O V
OV
Astakhova
V M
VM
D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000097:blood / Q000175:diagnosis* / Q000517:prevention & control; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D005260:Female; D006487:Hemostasis / Q000187:drug effects; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007414:Intestinal Neoplasms / Q000097:blood* / Q000601:surgery; D007420:Intestine, Large / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000031:analogs & derivatives / Q000627:therapeutic use; D011183:Postoperative Complications / Q000097:blood / Q000175:diagnosis* / Q000517:prevention & control; D011300:Preoperative Care; D013806:Theophylline / Q000031:analogs & derivatives / Q000627:therapeutic use
D000925:Anticoagulants; D004338:Drug Combinations; C034813:drotaverine, acephyllinate drug combination; D006493:Heparin; D013806:Theophylline; D010208:Papaverine