title: Comparative study of DNA adducts levels in white sucker fish (Catostomus commersoni) from the basin of the St. Lawrence River (Canada).
abstract: The levels of DNA adducts in the hepatic tissue of the white sucker fish species Catostomus commersoni were determined by 32P-postlabelling. The fish were caught at four sites: two sites near the city of Windsor (Québec, Canada) on the St. François River, a downstream tributary of the St. Lawrence River, and two sites in the St. Lawrence River itself, near the city of Montréal (Québec, Canada). The latter sites are known to be contaminated by many pollutants including polycyclic aromatic hydrocarbons. Total adduct levels in all fish ranged from 25.1-178.0 adducts per 10(9) nucleotides. White sucker from the selected sites of the St. Lawrence River had a significantly higher mean level of DNA adducts than those of the St. François River (129.4 vs 56.8, respectively). These results suggest that the effluents of many heavy industries (e.g. from a Soderberg aluminium plant) flowing in the St. Lawrence River are more likely to produce genotoxic damage to fish than those released in one of its tributary, and mainly associated to the activities of a small town and a nearby pulp and paper mill.
authors.affiliation: Unité Santé et environnement, Centre de recherche du Centre Hospitalier de l'Université Laval.
authors.forename: C
authors.initials: C
authors.lastname: el Adlouni
authors.forename: J
authors.initials: J
authors.lastname: Tremblay
authors.forename: P
authors.initials: P
authors.lastname: Walsh
authors.forename: J
authors.initials: J
authors.lastname: Lagueux
authors.forename: J
authors.initials: J
authors.lastname: Bureau
authors.forename: D
authors.initials: D
authors.lastname: Laliberte
authors.forename: G
authors.initials: G
authors.lastname: Keith
authors.forename: D
authors.initials: D
authors.lastname: Nadeau
authors.forename: G G
authors.initials: GG
authors.lastname: Poirier
mesh_terms: D000818:Animals; D003531:Cypriniformes / Q000235:genetics / Q000378:metabolism*; D018736:DNA Adducts / Q000032:analysis*; D004249:DNA Damage; D005618:Fresh Water; D007220:Industrial Waste; D008099:Liver / Q000737:chemistry; D011083:Polycyclic Compounds / Q000009:adverse effects; D011792:Quebec; D014874:Water Pollutants, Chemical / Q000009:adverse effects*
chemical_list: D018736:DNA Adducts; D007220:Industrial Waste; D011083:Polycyclic Compounds; D014874:Water Pollutants, Chemical