title: Stereotactic radiosurgery in children.
abstract: The role of stereotactic radiosurgery in the treatment of pediatric patients is still being explored. We report the Gamma Knife treatment of 33 patients under the age of 21, at the University of California, San Francisco, between the years 1991 and 1993. Treatment-related toxicity has been low. 10/14 patients treated for arteriovenous malformation (AVM) with follow-up > 1 month have shown partial or complete AVM obliteration. No patient has had a new hemorrhage after AVM treatment. In children with malignant tumors, treatment was well tolerated, although most patients, ultimately, had progressive disease. Stereotactic radiosurgery is logistically possible in the pediatric population. Its use in selected patients with AVMs seems appropriate, although its role in the treatment of malignant brain tumors remains to be defined.
authors.affiliation: University of California, San Francisco, USA.
authors.forename: W
authors.initials: W
authors.lastname: Wara
authors.forename: G
authors.initials: G
authors.lastname: Bauman
authors.forename: P
authors.initials: P
authors.lastname: Gutin
authors.forename: S
authors.initials: S
authors.lastname: Circillo
authors.forename: D
authors.initials: D
authors.lastname: Larson
authors.forename: M
authors.initials: M
authors.lastname: McDermott
authors.forename: P
authors.initials: P
authors.lastname: Sneed
authors.forename: L
authors.initials: L
authors.lastname: Verhey
authors.forename: V
authors.initials: V
authors.lastname: Smith
authors.forename: P
authors.initials: P
authors.lastname: Petti
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D002538:Intracranial Arteriovenous Malformations / Q000601:surgery*; D016634:Radiosurgery; D012189:Retrospective Studies; D016896:Treatment Outcome