title: The effect of iron on metabolism of vitamin C in chickens.
abstract: The objective of the paper was to show the effect of supplementation of iron on vitamin C synthesis in chickens. Iron administered per as caused than increase of vitamin C synthesis in chickens. The increase of vitamin C synthesis following iron supplementation is due to the alteration of L-gulono-gamma-oxidase activity in tissues; the enzyme taking part in last phase of vitamin C formation, and due to increase of D-glucuronic acid level, an intermediate product during vitamin C synthesis. High doses of iron cause the increase of vitamin C metabolism in chickens.
authors.affiliation: Department of Animal Physiology, Faculty of Veterinary Medicine, Agricultural University, Lublin, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Nagórna-Stasiak
authors.forename: J
authors.initials: J
authors.lastname: Lechowski
authors.forename: A
authors.initials: A
authors.lastname: Lazuga-Adamczyk
mesh_terms: D000311:Adrenal Glands / Q000201:enzymology; D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D002645:Chickens / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005527:Food, Fortified; D005965:Glucuronates / Q000378:metabolism; D020723:Glucuronic Acid; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000378:metabolism; D007422:Intestines / Q000201:enzymology; D007501:Iron / Q000008:administration & dosage / Q000494:pharmacology*; D007668:Kidney / Q000201:enzymology; D050544:L-Gulonolactone Oxidase; D008099:Liver / Q000201:enzymology; D018482:Muscle, Skeletal / Q000201:enzymology; D013270:Stomach / Q000201:enzymology; D013401:Sugar Alcohol Dehydrogenases / Q000378:metabolism / Q000502:physiology
chemical_list: D005965:Glucuronates; D006454:Hemoglobins; D020723:Glucuronic Acid; D007501:Iron; D013401:Sugar Alcohol Dehydrogenases; D050544:L-Gulonolactone Oxidase; D001205:Ascorbic Acid