title: Pulverulent nuclear cataract in the Norwegian buhund.
abstract: Pulverulent cataracts were diagnosed in 52 of 102 Norwegian buhunds, with both sexes being equally affected. All the dogs were otherwise considered clinically healthy. Initial lens changes were visible from six and a half weeks of age as small dots parallel to the suture lines behind the nucleus. Gradually, the opacities along the suture lines became more opaque until, by the age of four to five and a half years, they had progressed to involve the fetal nucleus which then resembled a ball of candy floss. The outer part, the adult nucleus, usually remained clear, and the cortex was not involved. The ages of the dogs in the present study ranged from three and a half weeks to 12 years at first examination. An outcross of an affected bitch to a mixed-breed dog resulted in three puppies, of which two were affected. The retinas could be evaluated in all the examined dogs, and revealed no abnormalities except for one case of focal retinopathy. In addition to the pulverulent cataracts, 10 cases of cortical cataracts were diagnosed, three of which also had pulverulent cataracts. Based on the pedigrees, an autosomal dominant mode of inheritance with a high degree of penetrance is suggested for pulverulent cataract.
authors.affiliation: Department of Small Animal Clinical Sciences, Norwegian College of Veterinary Medicine, Oslo, Norway.
authors.forename: E
authors.initials: E
authors.lastname: Bjerkås
authors.forename: M B
authors.initials: MB
authors.lastname: Haaland
mesh_terms: D000375:Aging / Q000473:pathology; D000818:Animals; D001947:Breeding; D002386:Cataract / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000235:genetics* / Q000473:pathology*; D004285:Dogs; D005260:Female; D005799:Genes, Dominant; D007907:Lens Nucleus, Crystalline / Q000473:pathology*; D008297:Male; D010375:Pedigree