Malignant fibrous histiocytoma of the spermatic cord.
OBJECTIVE
We analyzed 26 cases of malignant fibrous histiocytoma and report our conclusions regarding the diagnosis, pathology and treatment of this unusual tumor.


METHODS
We reviewed 25 previously reported cases of malignant fibrous histiocytoma of the spermatic cord and report 1 additional case. Further data on patient survival and tumor recurrence rates were obtained from some of the previous authors.


RESULTS
Of 26 patients 5 are long-term survivors (more than 5 years). Longest reported followup is 14 years. However, malignant fibrous histiocytoma has recurred as late as 6 years after surgery. To date 4 deaths have been reported, including 1 unrelated to the tumor and 3 from metastatic tumor. Disease recurred in 5 patients. In no case was there local lymph node involvement at surgery.


CONCLUSIONS
Malignant fibrous histiocytoma presents earlier in the spermatic cord than at other sites and seems to have a more favorable prognosis. Ultrasound may aid in the diagnosis. Definitive treatment is radical orchiectomy but localized radiotherapy may decrease local recurrence rates. Satellite lesions at surgery indicate a poorer prognosis. Metastases may develop late in the lungs or mesentery, and so long-term followup is necessary.
Glazier
D B
DB
Department of Surgery, Robert Wood Johnson University Hospital, New Brunswick, New Jersey 08903-0019, USA.
Vates
T S
TS
Cummings
K B
KB
Pickens
R L
RL
D005500:Follow-Up Studies; D005834:Genital Neoplasms, Male / Q000473:pathology / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D013085:Spermatic Cord