Surface properties and biocompatibility of A-B-A type block copolymer membranes consisting of poly(gamma-benzyl-L-glutamate) as the A component and polyisoprene as the B component.
The surface characteristics of A-B-A type triblock copolymer (GIG) membranes consisting of alpha-helical poly (gamma-benzyl-L-glutamate) (PBLG) as the A component and polyisoprene (PI) as the B component were investigated by X-ray photoelectron spectroscopy (XPS) and contact angle measurements. The XPS measurements showed the copolymer composition of the outermost surface to be quite different from the bulk composition. Results of contact angle measurements indicated the existence of an interfacial region between the alpha-helical A component and the B component at the surfaces of the block copolymer membranes. Finally, the results of in vivo tests on tissue compatibility indicate that the GIG block copolymer membranes have good biocompatibility.
Yoda
R
R
Research and Development Center, Nippon Zeon Co. Ltd., Kanagawa, Japan.
Komatsuzaki
S
S
Hayashi
T
T
D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry*; D001769:Blood; D002070:Butadienes / Q000138:chemical synthesis / Q000737:chemistry*; D020724:Elastomers; D045782:Hemiterpenes; D066298:In Vitro Techniques; D008422:Materials Testing; D010420:Pentanes; D011099:Polyglutamic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D011817:Rabbits; D013052:Spectrometry, X-Ray Emission; D013499:Surface Properties; D014867:Water / Q000737:chemistry
D001672:Biocompatible Materials; D002070:Butadienes; D020724:Elastomers; D045782:Hemiterpenes; D010420:Pentanes; D011108:Polymers; D014867:Water; C005059:isoprene; C003172:poly-gamma-benzyl-L-glutamate; D011099:Polyglutamic Acid; C028834:polybutadiene