title: Anaerobic tissue-dissolving abilities of calcium hydroxide and sodium hypochlorite.
abstract: Closed root canals likely have an oxygen-free environment; most bacteria in canals are anaerobic. These bacteria and other debris are difficult to remove. Unknown is tissue dissolution with chemicals under these anaerobic conditions. This study evaluated and compared dissolving properties of calcium hydroxide (Ca(OH)2) and sodium hypochlorite (NaOCl) on bovine pulp tissue in aerobic and anaerobic environments. Sixty bovine pulp specimens were dried, then randomly divided into six groups. Groups A and B were immersed in Ca(OH)2 + water solution, whereas group C and D were in 2.5% NaOCl. Groups E and F (controls) specimens were placed in distilled water. Groups A, C, and E were incubated anaerobically, and groups B, D, and F were incubated under regular atmospheric conditions, all for 7 days. Percentages of weight loss were compared between groups. Results showed the following: (a) both chemicals partially dissolved pulp tissue, (b) anaerobic environment did not alter tissue-dissolving properties of Ca(OH)2 or NaOCl, and (c) Ca(OH)2 and NaOCl were equal and more effective than water.
authors.affiliation: Department of Restorative Dentistry, Veterans General Hospital, Taipei, Taiwan, ROC.
authors.forename: S F
authors.initials: SF
authors.lastname: Yang
authors.forename: E M
authors.initials: EM
authors.lastname: Rivera
authors.forename: K R
authors.initials: KR
authors.lastname: Baumgardner
authors.forename: R E
authors.initials: RE
authors.lastname: Walton
authors.forename: C
authors.initials: C
authors.lastname: Stanford
mesh_terms: D000693:Anaerobiosis; D000818:Animals; D002126:Calcium Hydroxide / Q000494:pharmacology*; D002417:Cattle; D003782:Dental Pulp / Q000187:drug effects*; D010100:Oxygen; D011897:Random Allocation; D012388:Root Canal Irrigants / Q000494:pharmacology*; D012973:Sodium Hypochlorite / Q000494:pharmacology*; D012997:Solvents / Q000494:pharmacology*; D018709:Statistics, Nonparametric
chemical_list: D012388:Root Canal Irrigants; D012997:Solvents; D012973:Sodium Hypochlorite; D002126:Calcium Hydroxide; D010100:Oxygen