title: Cellular fibroma of the ovary with Meigs' syndrome and elevated CA-125. A case report.
abstract: BACKGROUND
  Cellular fibroma of the ovary is an uncommon benign tumor. When associated with Meigs' syndrome, it can produce a clinical picture similar to that of ovarian carcinoma.
  
  
  METHODS
  A 73-year-old nulligravida was admitted to the hospital with progressive cachexia, ascites, a right pleural effusion and a 15-cm pelvic mass. The serum CA-125 level was 1,780. Due to a high suspicion of ovarian carcinoma, the patient underwent exploratory laparotomy, total abdominal hysterectomy/bilateral salpingooophorectomy and surgical staging for a frozen section diagnosis of sarcoma. Permanent histology revealed the tumor to be a cellular fibroma, and the CA-125 levels fell to normal postoperatively.
  
  
  CONCLUSIONS
  Since benign ovarian tumors may mimic carcinoma, laparotomy and appropriate surgical staging are essential for the final diagnosis.
authors.affiliation: Department of Medicine and Gynecology, Graduate Hospital, Philadelphia, Pennsylvania 19125, USA.
authors.forename: M
authors.initials: M
authors.lastname: Siddiqui
authors.forename: D B
authors.initials: DB
authors.lastname: Toub
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000097:blood*; D005260:Female; D005350:Fibroma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008539:Meigs Syndrome / Q000175:diagnosis* / Q000473:pathology
chemical_list: D002272:Carcinoembryonic Antigen