title: Experimental infection with Yersinia enterocolitica serovar 0:8 in beagle dogs.
abstract: Dogs were challenged orally with Yersinia enterocolitica serovar 0:8 biovar 1 for assessment of the infectivity of 0:8 bacteria. The bacteria were shed in the feces for 7-21 days following oral challenge. They were also recovered from intestinal contents and small intestinal Peyer's patches, but not from deeper organs of dogs euthanized 3 and 7 days after oral challenge. Dogs challenged subsequently with 10(10) bacteria showed protection from establishment of the bacteria in the intestinal tract. High titers of serum O-agglutinins developed in the dogs challenged with the bacteria. No clinical or hematological abnormalities were observed. The possibility that dogs may be a source of infection of 0:8 bacteria to human is discussed.
authors.affiliation: Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan. eisei@cc.tuat.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Hayashidani
authors.forename: K
authors.initials: K
authors.lastname: Kaneko
authors.forename: K
authors.initials: K
authors.lastname: Sakurai
authors.forename: M
authors.initials: M
authors.lastname: Ogawa
mesh_terms: D000373:Agglutinins / Q000097:blood; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D004197:Disease Reservoirs; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005243:Feces / Q000382:microbiology; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D007422:Intestines / Q000382:microbiology; D015009:Yersinia Infections / Q000382:microbiology / Q000662:veterinary*; D015008:Yersinia enterocolitica / Q000472:pathogenicity*
chemical_list: D000373:Agglutinins; D000907:Antibodies, Bacterial; D007136:Immunoglobulins