Presynaptic localization of mu-opioid receptor-like immunoreactivity in retinal axon terminals within the terminal nuclei of the accessory optic tract: a light and electron microscope study in the rat.
Neuropil within the terminal nuclei of the accessory optic tract of the rat showed intense to moderate mu-opioid receptor-like immunoreactivity (MOR-LI). After unilateral enucleation, MOR-LI within the terminal nuclei almost disappeared or was markedly reduced on the side contralateral to the operation. Electron microscopy revealed that MOR-LI axon terminals within the terminal nuclei were filled with round synaptic vesicles and in asymmetric synaptic contact mainly with dendritic profiles, and occasionally with somatic profiles.
Ding
Y Q
YQ
Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan.
Nomura
S
S
Kaneko
T
T
Mizuno
N
N
D000818:Animals; D015353:Eye Enucleation; D007150:Immunohistochemistry; D008636:Mesencephalon / Q000502:physiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000378:metabolism / Q000648:ultrastructure; D017729:Presynaptic Terminals / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D017450:Receptors, Opioid, mu / Q000378:metabolism* / Q000648:ultrastructure; D012160:Retina / Q000378:metabolism / Q000648:ultrastructure; D014795:Visual Pathways / Q000378:metabolism* / Q000648:ultrastructure
D017450:Receptors, Opioid, mu