[Therapeutic implication of the decreased intrathyroidal iodine pool after partial thyroidectomy for simple goiter].
The residual intrathyroidal iodine pool has not been theoretically estimated in 65 subjects from Brussels submitted to partial thyroidectomy for simple goitre. The initial pool was found to be 6.28 mg +/- 3.15. The least invasive form of thyroidectomy (lobectomy) would have reduced this pool to approximately 4 mg and subtotal thyroidectomy to less than 0.5 mg. Various observations lead to the conclusion that the critical level of the thyroidal pool that would maintain euthyroidism lies near 2 to 3 mg. It is therefore concluded that a substitution therapy should be recommended after partial thyroidectomy for simple goitre in areas with relative alimentary iodine deficiency.
Jonckheer
M H
MH
Service de Médecine Nucléaire, Hôpital Académique de la Vrije Universiteit Brussel, Belgique.
Lamote
J
J
D006042:Goiter / Q000601:surgery*; D006044:Goiter, Nodular / Q000601:surgery; D006801:Humans; D007455:Iodine / Q000172:deficiency*; D011184:Postoperative Period; D013961:Thyroid Gland / Q000737:chemistry*; D013965:Thyroidectomy / Q000379:methods*
D007455:Iodine