title: Axial and lateral resolution of rotational intravascular ultrasound: in vitro observations and diagnostic implications.
abstract: OBJECTIVE
  To determine the axial and lateral resolution of a rotating intravascular ultrasound system and the diagnostic implications for the diagnosis of early artherosclerosis.
  
  
  METHODS
  The resolution of a 20 MHz rotating transducer was tested in a specially designed high-resolution phantom and in five aortic autopsy specimens with varying degrees of early atherosclerosis.
  
  
  RESULTS
  The best lateral resolution is at the minimal distance between transducer and object. Measurements in the wire phantom showed this to be better than 0.43 mm. This is less than the axial resolution which is better than 0.13 mm. Decreasing lateral resolution with increasing distance between transducer and object is manifested by arcing and overestimation of the extent of focal atherosclerotic lesions.
  
  
  CONCLUSIONS
  Axial resolution is significantly better than lateral resolution. Rapid deterioration of lateral resolution affects the diagnostic ability to characterize the extent of early atherosclerosis. Eccentric positioning of the transducer tip, particularly in larger vessels, will therefore influence diagnostic accuracy in vivo.
authors.affiliation: Department of Radiology, University of Minnesota Hospital and Clinic, Minneapolis 55455, USA.
authors.forename: C E
authors.initials: CE
authors.lastname: Engeler
authors.forename: E R
authors.initials: ER
authors.lastname: Ritenour
authors.forename: K
authors.initials: K
authors.lastname: Amplatz
mesh_terms: D000293:Adolescent; D000328:Adult; D001018:Aortic Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D001161:Arteriosclerosis / Q000000981:diagnostic imaging* / Q000473:pathology; D016477:Artifacts; D004867:Equipment Design; D006801:Humans; D007083:Iliac Artery / Q000000981:diagnostic imaging / Q000473:pathology; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D008961:Models, Structural; D014159:Transducers; D018084:Ultrasonography, Interventional / Q000295:instrumentation / Q000379:methods