A modified imaging sequence for accurate T2 measurements using NMR microscopy.
A modified spin-echo pulse sequence is described that enables accurate T2 measurements to be made in NMR microimaging experiments. The modified sequence eliminates cumulative diffusion losses that lead to an underestimation of the T2 relaxation time using conventional spin-echo pulse sequences. The approach is theoretically justified and confirmed in comparative experiments on phantoms.
Hsu
E W
EW
Biomedical Engineering Department, Johns Hopkins University Hospital, Baltimore, Maryland 21205, USA.
Schoeniger
J S
JS
Bowtell
R
R
Aiken
N R
NR
Horsman
A
A
Blackband
S J
SJ
D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D019047:Phantoms, Imaging