title: [Bladder dysfunctions in encephalomyelitis disseminata--drug and interventional therapeutic options].
abstract: Patients with disseminated encephalomyelitis have various urological presentations, ranging from pollakisuria to urge incontinence. After detailed evaluation (neuro-urological examination, urodynamic investigation) drug therapy and various interventional methods must be adapted to the individual manifestations. Patients with detrusor hyperreflexia are treated with oral anticholinergic agents (oxybutynin, trospium chloride, propiverine). Patients with urinary retention are recommended to be managed with clean intermittent (self)-catheterisation. The various interventional therapeutic options (bladder denervation, electrostimulation, local treatment with botulinum toxin) and the surgical therapy (sacral deafferentation and anterior root stimulation, bladder neck closure and cystostomy, sphincterotomy or augmentation cystoplasty) must be reserved for special cases.
authors.affiliation: Klinik für Urologie und Kinderurologie, Universität des Saarlandes, Homburg/Saar.
authors.forename: U
authors.initials: U
authors.lastname: Zwergel
authors.forename: W H
authors.initials: WH
authors.lastname: Jost
authors.forename: T
authors.initials: T
authors.lastname: Lindenmeir
authors.forename: T
authors.initials: T
authors.lastname: Zwergel
mesh_terms: D018680:Cholinergic Antagonists / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D006801:Humans; D009103:Multiple Sclerosis / Q000503:physiopathology / Q000628:therapy*; D009420:Nervous System / Q000503:physiopathology; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000294:innervation; D014546:Urinary Catheterization; D014555:Urination Disorders / Q000503:physiopathology / Q000628:therapy*
chemical_list: D018680:Cholinergic Antagonists