Persistent lack of detectable HIV-1 antibody in a person with HIV infection--Utah, 1995.
Infection with human immunodeficiency virus (HIV) is diagnosed routinely by the enzyme immunoassay (EIA) for HIV-1 antibody; a nonreactive blood sample is designated as negative without further testing. However, one limitation of this screening algorithm is that a blood sample may be obtained from a patient with recent HIV infection before detectable HIV antibody is present ("window period"). This report describes a patient with confirmed HIV infection in whom EIAs for HIV antibody (HIV-EIAs) were persistently negative beyond the expected "window period."
D015492:AIDS Serodiagnosis; D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000276:immunology; D000328:Adult; D004279:DNA, Viral / Q000032:analysis; D015483:HIV Antibodies / Q000032:analysis* / Q000096:biosynthesis; D016655:HIV Core Protein p24 / Q000032:analysis; D015658:HIV Infections / Q000175:diagnosis / Q000276:immunology* / Q000635:transmission; D018023:HIV Seronegativity; D015497:HIV-1 / Q000235:genetics / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D017720:Molecular Epidemiology; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis / Q000276:immunology; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D014589:Utah
D004279:DNA, Viral; D015483:HIV Antibodies; D016655:HIV Core Protein p24