Determination of ipriflavone and its synthetic impurities by high-performance liquid chromatography using diode-array detection.
A simple, accurate and rapid method for the determination of ipriflavone and its synthetic impurities has been developed. It consists in RP-HPLC separation and identification of the impurities from their UV spectra using photodiode-array detection. The method has been validated and shows good specificity, accuracy, precision and sensitivity.
Sustacha
K
K
Departamento de Investigatión, FAES SA, Bilbao, Spain.
Chacón
M
M
Lucero
M L
ML
Orjales
A
A
D002851:Chromatography, High Pressure Liquid / Q000379:methods* / Q000706:statistics & numerical data; D004340:Drug Contamination; D007529:Isoflavones / Q000032:analysis*; D012680:Sensitivity and Specificity; D013053:Spectrophotometry
D007529:Isoflavones; C018986:ipriflavone