IgA deficiency and psoriasis: relevance of IgA in the pathogenesis of psoriasis.
A psoriatic patient with absolute deficiency of IgA is reported. The manifestations of psoriasis appeared at the age of 6 months and proved to be resistant to various treatments. The present case report and the data available in the literature on IgA and psoriasis all converge on the hypothesis that IgA is a systemic factor which belongs to the 'off switches' of the psoriatic process.
van de Kerkhof
P C
PC
Department of Dermatology, University Hospital Nijmegen, The Netherlands.
Steijlen
P M
PM
D000328:Adult; D004351:Drug Resistance; D006801:Humans; D017098:IgA Deficiency / Q000150:complications*; D007070:Immunoglobulin A / Q000032:analysis / Q000276:immunology*; D007223:Infant; D008297:Male; D011565:Psoriasis / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology
D007070:Immunoglobulin A