title: A potential anti-oxidant protein in a ferrous iron-oxidizing Sulfolobus species.
abstract: The production of a 25 kDa protein was greatly increased when a sulfur- and ferrous iron-oxidizing species of Sulfolobus was switched from growth on tetrathionate to growth on ferrous iron. The gene encoding the protein was cloned and sequenced. The predicted amino sequence showed significant similarity to those of the alkyl hydroperoxide reductase/thiol specific anti-oxidant family of proteins that appear to be involved in responses to certain types of oxidative stress.
authors.affiliation: Department of Biological Sciences, University of Warwick, Coventry, UK.
authors.forename: N P
authors.initials: NP
authors.lastname: Burton
authors.forename: T D
authors.initials: TD
authors.lastname: Williams
authors.forename: P R
authors.initials: PR
authors.lastname: Norris
mesh_terms: D000595:Amino Acid Sequence; D000975:Antioxidants; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D005296:Ferrous Compounds / Q000378:metabolism; D005798:Genes, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000235:genetics; D010544:Peroxidases; D054464:Peroxiredoxins; D017421:Sequence Analysis; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D016944:Sulfolobus / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism
chemical_list: D000975:Antioxidants; D001426:Bacterial Proteins; D005296:Ferrous Compounds; C020748:ferrous sulfate; D010088:Oxidoreductases; D010544:Peroxidases; D054464:Peroxiredoxins