title: Radiofrequency catheter ablation of multiple morphologies of ventricular tachycardia by targeting a single region of the left ventricle.
abstract: BACKGROUND
  As treatment options for ventricular tachycardia (VT) continue to evolve, the use of radiofrequency catheter ablation is rapidly expanding. However, in the presence of multiple morphologies of VT, achieving successful results may seem less likely. We report two patients with multiple morphologies of VT who underwent successful radiofrequency ablation by application of radiofrequency energy to a single region in the left ventricle.
  
  
  RESULTS
  Two patients, each without any apparent cardiac dysfunction and a history of documented VT, were referred to our institution for further management. They underwent an electrophysiologic study and were found to have easily inducible VT, of three morphologies in one patient and two in the other. Using a transaortic approach, left ventricular mapping was performed for detecting a site with presystolic potentials, earliest ventricular activation, or both. Application of radiofrequency energy to a single area in the left ventricle resulted in the elimination of all previously inducible VT in each patient.
  
  
  CONCLUSIONS
  VTs with distinctly different morphologies can occur in patients with no detectable structural heart disease. These VT circuits may share a common pathway and, therefore, may readily be amenable to therapy with radiofrequency catheter ablation.
authors.affiliation: Electrophysiology Laboratory, Milwaukee Heart Institute, Sinai Samaritan Medical Center, Wisconsin 53233, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Underwood
authors.forename: S S
authors.initials: SS
authors.lastname: Deshpande
authors.forename: M
authors.initials: M
authors.lastname: Biehl
authors.forename: M
authors.initials: M
authors.lastname: Cowan
authors.forename: M
authors.initials: M
authors.lastname: Akhtar
authors.forename: M R
authors.initials: MR
authors.lastname: Jazayeri
mesh_terms: D000328:Adult; D017115:Catheter Ablation; D004562:Electrocardiography; D006352:Heart Ventricles / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017180:Tachycardia, Ventricular / Q000503:physiopathology / Q000601:surgery*