Right and left atrial phasic volumetric function in mildly symptomatic dilated and hypertrophic cardiomyopathy: cine MR imaging assessment.
OBJECTIVE
To characterize biatrial phasic volumetric function in dilated and hypertrophic cardiomyopathy with cine magnetic resonance (MR) imaging.


METHODS
Eight patients with dilated cardiomyopathy (mean age, 47 years), eight with hypertrophic cardiomyopathy (mean age, 39 years), and eight healthy subjects (mean age, 41 years) underwent cardiac-gated long-axis cine MR imaging of both atria.


RESULTS
Left atrial minimum volume averaged 94 mL +/- 37 (standard deviation) in dilated cardiomyopathy, 86 mL +/- 40 in hypertrophic cardiomyopathy, and 51 mL +/- 14 in control subjects (P = .04). Left atrial ejection fraction averaged 16% +/- 6 in dilated cardiomyopathy, 19% +/- 12 in hypertrophic cardiomyopathy, and 28% +/- 7 in control subjects (P = .03). Right atrial minimum volume and ejection fraction were not altered in either form of cardiomyopathy. The normalized filling and emptying rates of either atrium were decreased in both forms of cardiomyopathy.


CONCLUSIONS
In mildly symptomatic dilated and hypertrophic cardiomyopathy, and left atrium is enlarged and its relative cyclic volume changes are reduced. The right atrium is of normal size, but its reservoir function is compromised particularly in dilated cardiomyopathy. Three-dimensional volume measurements with cine MR imaging enable the exposure of altered atrial volumetric function.
Järvinen
V M
VM
Department of Diagnostic Radiology, Helsinki University Central Hospital, Finland.
Kupari
M M
MM
Poutanen
V P
VP
Hekali
P E
PE
D000328:Adult; D016275:Atrial Function / Q000502:physiology*; D002306:Cardiac Volume / Q000502:physiology; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000503:physiopathology*; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D006325:Heart Atria / Q000473:pathology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008875:Middle Aged; D013997:Time Factors