Bioactive isocoumarins and related metabolites from conifer endophytes.
Six new [1-4, 7, 9] and two known [6 and 8] metabolites have been isolated from culture filtrates of conifer endophyte strains of Canoplea elegantula. Their structures have been determined by spectroscopic means. Compound 1 was toxic to spruce budworm cells, and both 1 and 3 were toxic to spruce budworm larvae.
Findlay
J A
JA
Department of Chemistry, University of New Brunswick, Fredericton, Canada.
Buthelezi
S
S
Lavoie
R
R
Peña-Rodriguez
L
L
Miller
J D
JD
D000818:Animals; D002170:Canada; D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D007814:Larva; D010947:Plants, Toxic / Q000737:chemistry*
D003374:Coumarins; D007306:Insecticides