title: [Progress in the study of cyclic nucleotide phosphodiesterases].
abstract: There are five families of cyclic nucleotide phosphodiesterase isozymes, which have a common structure, but have different biochemical characteristics, physiologic functions and regulatory mechanisms. Various selective phosphodiesterase inhibitors may have potential uses for antiasthmatic, inotropic, vasodilative, antithrombotic and antidepressant drugs.
authors.affiliation: Division of Antiasthmatic Drug Research, Zhejiang Medical University, Hangzhou.
authors.forename: H L
authors.initials: HL
authors.lastname: Zhou
authors.forename: R L
authors.initials: RL
authors.lastname: Bian
mesh_terms: D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases / Q000737:chemistry / Q000502:physiology*; D000818:Animals; D000242:Cyclic AMP / Q000502:physiology; D006152:Cyclic GMP / Q000502:physiology; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000502:physiology*
chemical_list: D007527:Isoenzymes; D000242:Cyclic AMP; D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases; D006152:Cyclic GMP