Molecular characterisation of the genomic locus of the mouse MRP8 gene.
MRP8 is an inflammatory marker protein specifically expressed throughout the myeloid cell lineage in mouse and humans. Here the nucleotide sequence and the genomic structure of the mouse MRP8 gene (MM-MRP8) is presented. A strong homology between the mouse and human MRP8 promoters reflects the highly specific expression pattern of both genes and suggests that a conserved transcriptional machinery regulates these genes.
Nacken
W
W
Institute for Experimental Dermatology, Münster Medical School, Germany.
Manitz
M P
MP
Sorg
C
C
D000595:Amino Acid Sequence; D000818:Animals; D000943:Antigens, Differentiation / Q000737:chemistry / Q000235:genetics*; D001483:Base Sequence; D015139:Blotting, Southern; D002135:Calcium-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D040501:Calgranulin A; D003001:Cloning, Molecular; D017931:DNA Primers / Q000737:chemistry; D005091:Exons / Q000235:genetics; D006801:Humans; D051379:Mice; D008815:Mice, Inbred Strains; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D016385:TATA Box / Q000235:genetics
D000943:Antigens, Differentiation; D002135:Calcium-Binding Proteins; D040501:Calgranulin A; D017931:DNA Primers