Protein B: an important human IgA-binding reagent.
Protein B had a much higher affinity for human IgA than Jacalin, increasing the sensitivity and specificity of the measurement of total human IgA. Protein B, used as a capturing agent, greatly enhanced the measurement of antigen-specific IgA as compared to alpha chain-specific antibodies.
Grundy
M A
MA
Blake Laboratories Corporation, Great Neck, New York 11021, USA.
Blake
M S
MS
Murray
K
K
D000918:Antibody Specificity; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D018928:Immunity, Mucosal; D007070:Immunoglobulin A / Q000032:analysis / Q000378:metabolism*; D007369:Interferon Inducers / Q000276:immunology* / Q000378:metabolism; D007700:Kinetics; D037102:Lectins / Q000276:immunology* / Q000378:metabolism; D037121:Plant Lectins; D011485:Protein Binding; D011961:Receptors, Fc / Q000378:metabolism*; D012680:Sensitivity and Specificity
C045281:IgA receptor; D007070:Immunoglobulin A; D007369:Interferon Inducers; D037102:Lectins; D037121:Plant Lectins; D011961:Receptors, Fc; C043696:jacalin