Humoral graft-versus-host disease after pancreas transplantation with an ABO-compatible and Rh-nonidentical donor. Case report and a rationale for preoperative screening.
Severe hemolysis and graft ischemia complicating solitary pancreas transplantation with an ABO-compatible, Rh-negative, anti-D-positive donor to Rh-positive recipient is described in this article. A brief review of the literature is presented. A rationale for preoperative screening for red cell antibodies during solid organ transplantation in this special setting is discussed.
Sindhi
R
R
Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska, 68198.
Landmark
J
J
Stratta
R J
RJ
Cushing
K
K
Taylor
R J
RJ
D000017:ABO Blood-Group System; D000328:Adult; D003920:Diabetes Mellitus / Q000601:surgery; D005260:Female; D006086:Graft vs Host Disease; D006461:Hemolysis; D006648:Histocompatibility; D006801:Humans; D007518:Isoantibodies / Q000276:immunology; D010190:Pancreatic Neoplasms / Q000276:immunology*; D012204:Rh-Hr Blood-Group System
D000017:ABO Blood-Group System; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System