title: A contemporary analysis of acute mastoiditis.
abstract: BACKGROUND
  Acute mastoiditis persists as a serious infection despite a dramatic decline in incidence coincident with the introduction of antibiotic therapy.
  
  
  OBJECTIVE
  To assist the contemporary practitioner in the recognition and management of acute mastoiditis through the assessment of a large series of patients.
  
  
  METHODS
  Retrospective case series comprising 124 patients with acute mastoiditis.
  
  
  METHODS
  Pediatric and adult otology referral center.
  
  
  METHODS
  Selected clinical parameters. Risk factors for necessity of surgical intervention and for increased length of hospitalization were analyzed by a stepwise logistic regression model.
  
  
  RESULTS
  A history of antecedent acute otitis media was absent in 45% of patients. Pain (98%) was the most common presenting symptom. Physical signs included an abnormal-appearing tympanic membrane (88%), fever (83%), a narrowed external auditory canal (80%), and postauricular edema (76%). Streptococcus pneumoniae was the most commonly isolated organism. Mastoid surgery was required in 62% of the patients. An elevated white blood cell count (relative risk [RR], 7.4; P < .01), proptosis of the auricle (RR, 4.5; P = .03), and fever on admission (RR, 7.3; P = .05) were risk factors for surgical intervention. All 33 patients with complications (27%) proceeded to surgical intervention. The average length of hospital stay was 7.9 days. The strongest predictor for an increased length of hospital stay was whether the patient required surgery (RR, 3.7; P = .002).
  
  
  CONCLUSIONS
  Acute mastoiditis remains a potentially serious otologic infection. Not all patients present with a classic history or physical examination. Therapeutic mastoidectomy is often required.
authors.affiliation: Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, USA.
authors.forename: R E
authors.initials: RE
authors.lastname: Gliklich
authors.forename: R D
authors.initials: RD
authors.lastname: Eavey
authors.forename: R A
authors.initials: RA
authors.lastname: Iannuzzi
authors.forename: A E
authors.initials: AE
authors.lastname: Camacho
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D007964:Leukocytosis / Q000209:etiology; D016015:Logistic Models; D008297:Male; D008417:Mastoiditis / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery*; D010146:Pain / Q000209:etiology; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012306:Risk; D012307:Risk Factors