title: Secondary arterial hypertension linked to Freon exposure.
abstract: Freons are generally considered to be minimally toxic. There are no reports in the literature of Freons causing secondary arterial hypertension. We report two cases of acute, massive Freon exposure that preceded secondary arterial hypertension. We hypothesize that the arterial hypertension was precipitated by renal proximal tubular damage, although several other mechanisms are possible.
authors.affiliation: Naval School of Health Sciences Bethesda Detachment, Fort Sam Houston, Tex., USA.
authors.forename: V M
authors.initials: VM
authors.lastname: Voge
mesh_terms: D000328:Adult; D001288:Attention / Q000187:drug effects; D064227:Chlorofluorocarbons, Ethane; D005617:Chlorofluorocarbons, Methane / Q000009:adverse effects*; D004844:Epistaxis / Q000139:chemically induced; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D007687:Kidney Tubules, Proximal / Q000187:drug effects; D008297:Male; D008569:Memory Disorders / Q000139:chemically induced; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D014786:Vision Disorders / Q000139:chemically induced
chemical_list: D064227:Chlorofluorocarbons, Ethane; D005617:Chlorofluorocarbons, Methane; C007786:1,1,2-trichloro-1,2,2-trifluoroethane; C009755:fluorocarbon 22; C007782:dichlorodifluoromethane