title: Mechanisms of neuronal degeneration in Alzheimer's disease.
authors.affiliation: Department of Neurology, Harvard Medical School, The Children's Hospital, Boston, Massachusetts 02115, USA.
authors.forename: B A
authors.initials: BA
authors.lastname: Yankner
mesh_terms: D000483:Alleles; D000544:Alzheimer Disease / Q000473:pathology* / Q000503:physiopathology*; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism*; D000818:Animals; D001057:Apolipoproteins E / Q000378:metabolism; D003704:Dementia / Q000209:etiology; D004195:Disease Models, Animal; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D009410:Nerve Degeneration; D010084:Oxidation-Reduction; D053764:Presenilin-1; D053766:Presenilin-2
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D001057:Apolipoproteins E; D008565:Membrane Proteins; C508853:PSEN1 protein, human; C508861:PSEN2 protein, human; D053764:Presenilin-1; D053766:Presenilin-2; C095101:Psen2 protein, mouse