Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome: spontaneous remission in a 15-year-old girl.
Acanthosis nigricans is associated with many diseases, including internal malignancies, genetic disorders, and endocrine abnormalities. Insulin resistance frequently accompanies endocrine-associated acanthosis nigricans. We describe a patient with acanthosis nigricans associated with hyperandrogenism and extreme insulin resistance that spontaneously resolved after a marked decrease in insulin receptor antibodies.
Esperanza
L E
LE
University of South Florida College of Medicine, Tampa 33612, USA.
Fenske
N A
NA
D000052:Acanthosis Nigricans / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D000293:Adolescent; D005260:Female; D006801:Humans; D017588:Hyperandrogenism / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D007333:Insulin Resistance; D012075:Remission, Spontaneous; D012867:Skin / Q000473:pathology; D013577:Syndrome