Kalimantacins A, B and C, novel antibiotics from Alcaligenes sp. YL-02632S. I. Taxonomy, fermentation, isolation and biological properties.
Novel antibacterial antibiotics, kalimantacins A, B and C, have been isolated from the fermentation broth of Alcaligenes sp. YL-02632S. In this paper, the taxonomy of the producing strain, fermentation, isolation and biological activities of kalimantacins are reported. Kalimantacins inhibit the growth of Staphylococcus aureus and S. epidermidis including multiple-drug resistant strains.
Kamigiri
K
K
Yamanouchi Pharmaceutical Co., Ltd., Tokyo, Japan.
Suzuki
Y
Y
Shibazaki
M
M
Morioka
M
M
Suzuki
K
K
Tokunaga
T
T
Setiawan
B
B
Rantiatmodjo
R M
RM
D000421:Alcaligenes / Q000145:classification / Q000378:metabolism*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002219:Carbamates / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D007941:Leukemia P388 / Q000473:pathology; D051379:Mice; D015394:Molecular Structure; D013211:Staphylococcus aureus / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000187:drug effects
D000900:Anti-Bacterial Agents; D002219:Carbamates; D005231:Fatty Acids, Unsaturated; C099202:kalimantacin C; C099201:kalimantacin A