MHC expression of African green monkeys of Barbados is limited in heterogeneity.
Major histocompatibility complex expression of activated peripheral blood lymphocytes of captive African green monkeys from Barbados and from Africa were analyzed biochemically; class I molecules by one-dimensional isoelectric focusing and class II DR molecules by one-dimensional nonequilibrium pH gradient electrophoresis. Much less diversity was observed in the major histocompatability molecule expression of the African green monkeys of Barbados than in the African cohort.
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Harvard Medical School, New England Regional Primate Research Center, Southborough, MA, USA.
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D000349:Africa; D000818:Animals; D001460:Barbados; D002522:Chlorocebus aethiops / Q000276:immunology*; D015870:Gene Expression; D014644:Genetic Variation; D005843:Geography; D006684:HLA-DR Antigens / Q000032:analysis / Q000096:biosynthesis / Q000302:isolation & purification; D015395:Histocompatibility Antigens Class I / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification; D000949:Histocompatibility Antigens Class II / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification; D007525:Isoelectric Focusing; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008285:Major Histocompatibility Complex
D006684:HLA-DR Antigens; D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II