Procalcitonin as a marker for the early diagnosis of neonatal infection.
Serum procalcitonin was determined in newborn infants at the time of admission to the pediatrics or obstetrics unit. Increased levels were found in all neonates with bacterial sepsis. Neonates with viral infection, bacterial colonization, or neonatal distress had normal or slightly increased levels. These data suggest that procalcitonin might be of value in diagnosing neonatal sepsis.
Gendrel
D
D
Département de Pédiatrie, Hôpital Saint-Vincent-de-Paul, Paris, France.
Assicot
M
M
Raymond
J
J
Moulin
F
F
Francoual
C
C
Badoual
J
J
Bohuon
C
C
D001424:Bacterial Infections / Q000097:blood; D015415:Biomarkers / Q000097:blood; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D011446:Prospective Studies; D011498:Protein Precursors / Q000097:blood*; D018805:Sepsis / Q000097:blood*; D014777:Virus Diseases / Q000097:blood
D015415:Biomarkers; C000606589:CALCA protein, human; D006023:Glycoproteins; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide