[Mixed carcinoid-carcinoma of the stomach].
Bioptical observation of a mixed carcinoid-carcinoma in a 75-year-old man's stomach was described. The subcardial tumour was 10-7 cm in diameter with secondaries in perigastric lymph nodes. A well differentiated adenocarcinoma with mucus production formed a minor marginal part of the carcinoid which expressed immunohistochemical markers common in gut cancers: carcinoembryonic antigen, epithelial membrane antigen and some cytokeratins. The well differentiated adenocarcinoma expressed different cytokeratins detected by AE1-AE3 antibody. The carcinoid was positive with Grimelius impregnation and strongly positive with chromogranin A and synaptophysin bound antibodies. Transition of both the tumour types was continuous.
Macák
J
J
Oddĕlení patologie Fakultní nemocnice, Olomouc.
Jezdinská
V
V
D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology*; D000368:Aged; D002276:Carcinoid Tumor / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D013274:Stomach Neoplasms / Q000737:chemistry / Q000473:pathology*