Lung transplantation in chronic airflow limitation.
Lung transplantation is an option for appropriately selected patients with end-stage chronic airflow limitation. The functional results have been excellent after single or bilateral lung transplantation, and the medium-term survival results have been good. Obliterative bronchiolitis, however, thought to be a manifestation of chronic rejection, occurs in approximately 40% of recipients, and it is the major cause of late morbidity and mortality in lung transplant recipients.
Lynch
J P
JP
Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Trulock
E P
EP
D000075202:Contraindications; D005541:Forced Expiratory Volume; D006801:Humans; D008171:Lung Diseases / Q000601:surgery; D008173:Lung Diseases, Obstructive / Q000503:physiopathology / Q000601:surgery*; D016040:Lung Transplantation / Q000379:methods; D018579:Patient Selection; D019896:alpha 1-Antitrypsin Deficiency