SarCNU (2-chloroethyl-3-sarcosinamide-1-nitrosourea): a novel analogue of chloroethylnitrosourea that is transported by the catecholamine uptake2 carrier, which mediates increased cytotoxicity.
Panasci
L C
LC
Lady Davis Institute of Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada.
Marcantonio
D
D
Noë
A J
AJ
D001692:Biological Transport; D002330:Carmustine / Q000031:analogs & derivatives* / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism*; D050482:Catecholamine Plasma Membrane Transport Proteins; D002395:Catecholamines / Q000378:metabolism; D006801:Humans; D026901:Membrane Transport Proteins; D012521:Sarcosine / Q000031:analogs & derivatives / Q000378:metabolism; D014407:Tumor Cells, Cultured
D002352:Carrier Proteins; D050482:Catecholamine Plasma Membrane Transport Proteins; D002395:Catecholamines; D026901:Membrane Transport Proteins; C039977:N-methylglycinamide; C044565:2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide; D002330:Carmustine; D012521:Sarcosine