Gcs1, a gene encoding gamma-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe.
By complementation of a mutant resistant to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) we have identified the gcs1 gene, encoding a putative gamma-glutamylcysteine synthetase. The gene is possibly interrupted by two introns and has 49% identical and 80% similar amino acids compared with the homologous protein from rat. In comparison with the Saccharomyces cerevisiae homologue it possesses 41% identical and 74% similar amino acids.
Coblenz
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Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälische Technische Hochschule Aachen, Germany.
Wolf
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D000595:Amino Acid Sequence; D001483:Base Sequence; D005800:Genes, Fungal; D005721:Glutamate-Cysteine Ligase / Q000737:chemistry / Q000235:genetics*; D007438:Introns; D008969:Molecular Sequence Data; D012568:Schizosaccharomyces / Q000201:enzymology / Q000235:genetics*
D005721:Glutamate-Cysteine Ligase