title: Truncus arteriosus repair: influence of techniques of right ventricular outflow tract reconstruction.
abstract: Fifty-six consecutive patients underwent total correction of truncus arteriosus. Median age at repair was 41 days, with a range of 2 days to 8 months. In 71% the operation was done in the first 2 months of life. Nine patients had complex forms of truncus and 11 patients had aortic insufficiency. The truncal aortic root was transected, which provides a clear exposure of the coronary ostia. The aorta was reconstructed by direct end-to-end anastomosis, and the truncal valve was preserved in every case. Several different techniques were used for pulmonary reconstruction, including three types of anatomic reconstruction of the pulmonary valve with a trisigmoid leaflet system and two types of nonanatomic reconstruction. The anatomic techniques included use of 33 Dacron valved conduits, eight homograft valved conduits, and one porcine aortic root bioprosthesis. The nonanatomic reconstructions included direct anastomosis to the right ventricle in nine patients and insertion of autologous pericardial valved conduits in five. The hospital mortality was 16% (9/56; 95% confidence limits, 2% to 30%). Multivariate analysis outlines two independent incremental risk factors for hospital death: nonanatomic pulmonary valve reconstruction techniques and age younger than 1 month. The hospital mortality was 7.1% in the group with anatomic pulmonary valve reconstruction versus 43% in the group with nonanatomic pulmonary valve reconstruction (p = 0.015). The hospital mortality was 5.7% in those older than 1 month versus 33% in those younger than 1 month of age (p = 0.04). There were two late deaths. The actuarial freedom from reoperation and angioplasty at 7 years was 100% for patients receiving pericardial conduits, 80% for those undergoing direct anastomosis, 77% for those receiving Dacron conduits, and only 43% for those receiving homografts (p = 0.02). In conclusion, anatomic reconstruction of the pulmonary valve seems important at the time of the operation, age younger than 1 month remains an incremental risk factor, and the truncal valve can be preserved.
authors.affiliation: Department of Pediatric Cardiac Surgery, Marie Lannelongue Hospital, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Lacour-Gayet
authors.forename: A
authors.initials: A
authors.lastname: Serraf
authors.forename: T
authors.initials: T
authors.lastname: Komiya
authors.forename: M
authors.initials: M
authors.lastname: Sousa-Uva
authors.forename: J
authors.initials: J
authors.lastname: Bruniaux
authors.forename: A
authors.initials: A
authors.lastname: Touchot
authors.forename: D
authors.initials: D
authors.lastname: Roux
authors.forename: P
authors.initials: P
authors.lastname: Neuville
authors.forename: C
authors.initials: C
authors.lastname: Planché
mesh_terms: D000367:Age Factors; D001022:Aortic Valve Insufficiency / Q000601:surgery; D001705:Bioprosthesis; D006348:Cardiac Surgical Procedures / Q000379:methods / Q000401:mortality; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019736:Prostheses and Implants; D011664:Pulmonary Valve / Q000601:surgery; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D014339:Truncus Arteriosus, Persistent / Q000401:mortality / Q000601:surgery*; D016278:Ventricular Function, Right; D014694:Ventricular Outflow Obstruction / Q000601:surgery