N-substituted-2-oxo-(2H)1-benzopyran-3-carboxamide derivatives with analgesic and/or diuretic activities.
The synthesis of N-substituted-2-oxo-(2H)1-Benzopyran-3-Carboxamide derivatives starting from semicarbazones or thiosemicarbazones and Carbon Suboxide (ratio 1:2) is described. Some compounds showed an interesting analgesic and/or diuretic activity in mice.
Artizzu
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Dipartimento Farmaco Chimico Tecnologico, Università di Cagliari, Italy.
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Loy
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Calignano
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D018712:Analgesics, Non-Narcotic / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D004232:Diuretics / Q000138:chemical synthesis* / Q000494:pharmacology; D008297:Male; D051379:Mice; D051381:Rats; D013329:Structure-Activity Relationship
D018712:Analgesics, Non-Narcotic; D004232:Diuretics