title: [Intravenous anesthesia in the horse: comparison of xylazine-ketamine and xylazine-tiletamine-zolazepam combinations].
abstract: Intravenous anesthesia in the horse: Comparison of xylazine-ketamine and xylaxine-tiletamine-zolazepam combinations. Six healthy adult horses were anesthetized twice at random with following intravenous combinations: 1.1 mg/kg of body weight (BW) of xylazine followed by 2.2 mg/kg BW of ketamine (X-K) and 1.1 mg/kg BW of xylazine followed by 1.65 mg/kg BW of tiletamine-zolazepam (X-TZ). The modifications of some cardiorespiratory parameters and the duration of anesthesia were evaluated and compared for the 2 protocols used. Few significant differences were observed between the 2 protocols in regard to the cardiorespiratory parameters measured. The respiratory rate was lower (7 breaths per minute) and the heart rate was higher (34 beats per minute) with the X-TZ combination. The duration of anesthesia with this technique was 33 +/- 3 minutes (X +/- Sx) and longer than with X-K (18 +/- minutes (X +/- Sx)). Superficial analgesia lasted 14,5 +/- 3 minutes with the X-K combination and 31,7 +/- 3,2 minutes for the X-TZ combination. The 2 protocols are associated with a reduction of PaO2.
authors.affiliation: Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Cuvelliez
authors.forename: G
authors.initials: G
authors.lastname: Rosseel
authors.forename: D
authors.initials: D
authors.lastname: Blais
authors.forename: Y
authors.initials: Y
authors.lastname: Salmon
authors.forename: E
authors.initials: E
authors.lastname: Troncy
authors.forename: N
authors.initials: N
authors.lastname: Larivière
mesh_terms: D000771:Anesthesia, Intravenous / Q000662:veterinary*; D000778:Anesthetics, Dissociative; D018686:Anesthetics, Intravenous; D000818:Animals; D004338:Drug Combinations; D006339:Heart Rate / Q000187:drug effects; D006736:Horses / Q000502:physiology*; D006993:Hypnotics and Sedatives; D007649:Ketamine; D008297:Male; D010100:Oxygen / Q000097:blood; D012119:Respiration / Q000187:drug effects; D013992:Tiletamine; D014991:Xylazine; D015041:Zolazepam
chemical_list: D000778:Anesthetics, Dissociative; D018686:Anesthetics, Intravenous; D004338:Drug Combinations; D006993:Hypnotics and Sedatives; D014991:Xylazine; D013992:Tiletamine; D007649:Ketamine; D015041:Zolazepam; D010100:Oxygen