title: Bile leakage following laparoscopic cholecystectomy.
abstract: Laparoscopic cholecystectomy (LC) is now the treatment of choice for gallstones, but there has been concern that bile leakage with LC is more frequent than after open cholecystectomy (OC). We have analyzed our experience of this complication with regard to both its incidence and management. From a consecutive series of 500 LC, in which both operative cholangiography and drainage of the gallbladder bed were routine, bile leakage was identified in ten patients (2%). There was no bile duct injury. Nine of the ten patients presented with bile in the drain within 24 h of operation and one patient presented 1 week after operation with a subphrenic collection. Of the ten patients, five settled spontaneously. Of the five remaining patients, two needed laparotomy--one for a subphrenic collection not responding to percutaneous drainage and one for biliary peritonitis. One patient was treated by relaparoscopy and suture of a duct of Luschka and one patient had successful percutaneous drainage of an infected collection; the fifth patient who presented with a late subphrenic collection of bile was shown at endoscopic retrograde cholangiopancreatography (ERCP) to have a cystic duct stump leak and was treated with an endoscopic stent. Bile leakage is seen more frequently after LC than OC for reasons that are currently unclear. We believe that the use of routine gallbladder bed drainage is justified for this reason alone. The majority of bile leaks settle either spontaneously or with minimally invasive intervention.
authors.affiliation: Leeds Institute for Minimally Invasive Therapy (LIMIT), United Kingdom.
authors.forename: J L
authors.initials: JL
authors.lastname: Albasini
authors.forename: V S
authors.initials: VS
authors.lastname: Aledo
authors.forename: S P
authors.initials: SP
authors.lastname: Dexter
authors.forename: J
authors.initials: J
authors.lastname: Marton
authors.forename: I G
authors.initials: IG
authors.lastname: Martin
authors.forename: M J
authors.initials: MJ
authors.lastname: McMahon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001646:Bile; D001652:Bile Ducts / Q000601:surgery; D002758:Cholangiography; D002760:Cholangiopancreatography, Endoscopic Retrograde; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D002769:Cholelithiasis / Q000601:surgery; D003549:Cystic Duct / Q000601:surgery; D004322:Drainage; D005260:Female; D005704:Gallbladder / Q000601:surgery; D006801:Humans; D015994:Incidence; D007813:Laparotomy; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D010538:Peritonitis / Q000209:etiology; D015641:Radiography, Interventional; D012086:Reoperation; D015607:Stents