High pressure effects on protein structure and function.
Many biochemists would regard pressure as a physical parameter mainly of theoretical interest and of rather limited value in experimental biochemistry. The goal of this overview is to show that pressure is a powerful tool for the study of proteins and modulation of enzymatic activity.
Mozhaev
V V
VV
Institut National de la Santé et de la Recherche Médicale, INSERM U 128, Montpellier, France.
Heremans
K
K
Frank
J
J
Masson
P
P
Balny
C
C
D001703:Biophysics / Q000379:methods; D004247:DNA / Q000378:metabolism; D006860:Hydrogen Bonding; D006874:Hydrostatic Pressure; D008958:Models, Molecular; D015394:Molecular Structure; D011487:Protein Conformation; D011489:Protein Denaturation; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D013329:Structure-Activity Relationship; D013696:Temperature
D011506:Proteins; D004247:DNA