The critical importance of stimulus intensity in intraoperative monitoring for partial dorsal rhizotomy.
During partial lumbosacral dorsal rhizotomy (PDR), intraoperative dorsal rootlet stimulation (drs) evokes motor responses, presumed to be reflexes, which are used to select rootlets for section. However, dr stimuli may also costimulate ventral root (vr) and evoke an M rather than a reflex response, the two being distinguishable only by comparison of response latencies after drs at two separate sites. In 15 consecutive spastic cerebral palsy patients undergoing PDR, we asked whether reflex and M responses were distinguishable on the basis of stimulus intensity (SI). For soleus H reflexes evoked by percutaneous tibial nerve stimulation, the SI for reflex afferents was usually subthreshold for exciting motor fibers. Similarly, for nerve roots, reflexes were evoked by drs at SIs generally less than that for M responses evoked by vr stimulation (vrs). In contrast, M responses evoked by drs required SIs that were on average 20 times greater. Finally, costimulation of contralateral vr after ipsilateral vrs occurred at SIs shown to evoke M responses after drs. We conclude that: (1) reflex and M responses evoked by drs are distinguishable on the basis of the required SI; and (2) drs employing SIs greater than required for vrs evokes M rather than reflex responses due to costimulation of ipsilateral and contralateral vr.
Logigian
E L
EL
Department of Medicine (Neurology), Brigham and Women's Hospital, Boston, Massachusetts, USA.
Shefner
J M
JM
Goumnerova
L
L
Scott
R M
RM
Soriano
S G
SG
Madsen
J
J
D002547:Cerebral Palsy / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D004558:Electric Stimulation; D006181:H-Reflex; D006801:Humans; D016343:Monitoring, Intraoperative; D009128:Muscle Spasticity / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery*; D012018:Reflex; D019051:Rhizotomy; D013126:Spinal Nerve Roots / Q000503:physiopathology; D013979:Tibial Nerve / Q000503:physiopathology