title: Pulmonary function tests in normal Indian children and changes in respiratory disorders.
abstract: To document the normal values of pulmonary function tests in children and changes occurring in their values with various respiratory disorders, a study was carried over a period of one year in 95 healthy controls (39 females and 56 males) of 8-13 years of age and 51 cases with respiratory disorders (bronchial asthma-31, pneumonia-10, empyema-10) of matched age, sex and height distribution. The lung functions studied were FVC, FEV1, FEV1/FVC, PEFR and FEF25-75%. In children with bronchial asthma, the FEV1/FVC%, PEFR and FEF25-75% were reduced in accordance with the severity of the disease. A typical restrictive pattern of equivalent decrease in FVC and FEV1 along with insignificant lowering of flow rates, i.e., PEFR and FEF25-75% was observed in pneumonia whereas in patients of empyema a combined pattern of significantly decreased FVC and FEV1 along with mildly reduced FEV1/FVC%, PEFR and FEF 25 75% was observed.
authors.affiliation: Department of Pediatrics, King George's Medical College, Lucknow.
authors.forename: A
authors.initials: A
authors.lastname: Srivastava
authors.forename: R K
authors.initials: RK
authors.lastname: Kapoor
authors.forename: P K
authors.initials: PK
authors.lastname: Misra
authors.forename: K L
authors.initials: KL
authors.lastname: Srivastava
authors.forename: S
authors.initials: S
authors.lastname: Thakur
authors.forename: N
authors.initials: N
authors.lastname: Shukla
mesh_terms: D000704:Analysis of Variance; D001249:Asthma / Q000503:physiopathology*; D016022:Case-Control Studies; D002648:Child; D004653:Empyema / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D011014:Pneumonia / Q000503:physiopathology*; D012016:Reference Values; D012129:Respiratory Function Tests; D012720:Severity of Illness Index; D013147:Spirometry