title: A halotolerant mutant of Saccharomyces cerevisiae.
abstract: FRD, a nuclear and dominant spontaneous mutant of Saccharomyces cerevisiae capable of growing in up to 2 M NaCl, was isolated. Compared with parental cells, the mutant cells have a lower intracellular Na+/K+ ratio, shorter generation times in the presence of 1 M NaCl, and alterations in gene expression.
authors.affiliation: Departamento de Genetica y Biologia Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico, D. F., Mexico.
authors.forename: R
authors.initials: R
authors.lastname: Gaxiola
authors.forename: M
authors.initials: M
authors.lastname: Corona
authors.forename: S
authors.initials: S
authors.lastname: Zinker
mesh_terms: D001692:Biological Transport; D002412:Cations / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005656:Fungal Proteins / Q000032:analysis; D009154:Mutation; D009997:Osmotic Pressure; D011188:Potassium / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D012965:Sodium Chloride / Q000378:metabolism*
chemical_list: D002412:Cations; D005656:Fungal Proteins; D012965:Sodium Chloride; D012964:Sodium; D011188:Potassium