Inactivation of C3 and C5 prolongs cardiac xenograft survival and decreases leukocyte infiltration in a model of delayed xenograft rejection.
Johnson
E M
EM
Department of Surgery, University of Minnesota, Minneapolis, USA.
Leventhal
J
J
Dalmasso
A P
AP
Goswitz
J
J
Simone
P
P
Chen
S
S
Matas
A J
AJ
D000818:Animals; D003176:Complement C3 / Q000037:antagonists & inhibitors / Q000276:immunology*; D003182:Complement C5 / Q000037:antagonists & inhibitors / Q000276:immunology*; D003183:Complement C6 / Q000276:immunology; D003169:Complement Inactivator Proteins / Q000276:immunology*; D006084:Graft Rejection / Q000276:immunology* / Q000517:prevention & control; D006085:Graft Survival; D006168:Guinea Pigs; D016027:Heart Transplantation / Q000276:immunology*; D006801:Humans; D007962:Leukocytes / Q000502:physiology; D051381:Rats; D011917:Rats, Inbred Lew; D014183:Transplantation, Heterologous / Q000276:immunology*
D003176:Complement C3; D003182:Complement C5; D003183:Complement C6; D003169:Complement Inactivator Proteins