title: Two-neuro networks. II. Leaky integrator pacemaker models.
abstract: The behavior of two pacemaker neurons simulated by leaky integrators and connected reciprocally by synapses was studied. In every case the firing of both neurons phase-locks. The resulting limit cycle may or may not show simultaneous firing of both neurons. When both synapses are excitatory, phase-locking with simultaneous neuronal firing is always present. When one synapse is excitatory and the other inhibitory, phase-locking is also present always, while the neurons may or may not fire simultaneously. For a restricted set of parameters, bistability appears; the initial conditions determine whether or not the limit cycle presents simultaneous firing. When both synapses are inhibitory, the system phase-locks without simultaneous firing for almost every set of parameters.
authors.affiliation: Instituto de Biologia, Facultad de Ciencias, Montevideo, Uruguay.
authors.forename: L
authors.initials: L
authors.lastname: Gómez
authors.forename: R
authors.initials: R
authors.lastname: Budelli
mesh_terms: D001683:Biological Clocks / Q000502:physiology*; D003198:Computer Simulation; D008433:Mathematics; D008564:Membrane Potentials; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*