title: FliH and fliI of Borrelia burgdorferi are similar to flagellar and virulence factor export proteins of other bacteria.
abstract: Two motility genes (fliH and fliI) of the Lyme disease spirochete Borrelia burgdorferi were cloned, physically mapped and sequenced, FliH and FliI showed extensive homology to the proteins involved in the export of flagellar components and to virulence factors found in both animal and plant bacterial pathogens. The results suggest that the flagellar apparatus and associated protein export pathway are well conserved in evolution.
authors.affiliation: Department of Microbiology, West Virginia University, Health Sciences Center, Morgantown 26506-9177, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Ge
authors.forename: I
authors.initials: I
authors.lastname: Old
authors.forename: I
authors.initials: I
authors.lastname: Saint Girons
authors.forename: D B
authors.initials: DB
authors.lastname: Yelton
authors.forename: N W
authors.initials: NW
authors.lastname: Charon
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry* / Q000235:genetics; D001483:Base Sequence; D015748:Borrelia burgdorferi Group / Q000737:chemistry* / Q000235:genetics; D003001:Cloning, Molecular; D017124:Conserved Sequence; D019143:Evolution, Molecular; D005407:Flagella / Q000737:chemistry; D008193:Lyme Disease / Q000382:microbiology; D008969:Molecular Sequence Data; D011506:Proteins / Q000737:chemistry* / Q000235:genetics; D006180:Proton-Translocating ATPases; D017421:Sequence Analysis; D017386:Sequence Homology, Amino Acid; D014774:Virulence / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D011506:Proteins; C069250:fliH protein, Bacteria; C069251:fliI protein, bacteria; D006180:Proton-Translocating ATPases