title: A toluene-tolerant mutant of Pseudomonas aeruginosa lacking the outer membrane protein F.
abstract: The outer membrane protein profiles of a toluene-tolerant mutant, Pseudomonas aeruginosa, strain PAK103, were compared with those of its parent strain PAO1161. Protein F (OprF), the most abundant outer membrane protein in the parental strain PAO1161, was missing in the toluene-tolerant strain PAK103. The absence of OprF may lead to the loss of toluene diffusion across in the outer membrane of the mutant cells.
authors.affiliation: DEEP STAR Group, Japan Marine Science and Technology Center, Yokosuka, Japan.
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.forename: T
authors.initials: T
authors.lastname: Komatsu
authors.forename: A
authors.initials: A
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Horikoshi
mesh_terms: D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics* / Q000378:metabolism*; D004361:Drug Tolerance; D008969:Molecular Sequence Data; D009154:Mutation; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism*; D014050:Toluene / Q000493:pharmacokinetics / Q000633:toxicity*
chemical_list: D001425:Bacterial Outer Membrane Proteins; D014050:Toluene