Synthesis and antimetastatic activity of 6-trichloroacetamido and 6-guanidino analogues of siastatin B.
Satoh
T
T
Institute of Microbial Chemistry, Tokyo, Japan.
Nishimura
Y
Y
Kondo
S
S
Takeuchi
T
T
Azetaka
M
M
Fukuyasu
H
H
Iizuka
Y
Y
Ohuchi
S
S
Shibahara
S
S
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D005966:Glucuronidase / Q000037:antagonists & inhibitors*; D006801:Humans; D050111:Imino Sugars; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008546:Melanoma, Experimental / Q000188:drug therapy / Q000556:secondary; D051379:Mice; D015394:Molecular Structure; D009557:Nipecotic Acids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D010880:Piperidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
C099339:6-(trichloroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid; C099338:6-(trifluoroacetamido)-3,4,5-trihydroxypiperidine-3-carboxylic acid; C099340:6-guanidino-4,5-dihydroxypiperidine-3-carboxylic acid; D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D050111:Imino Sugars; D009557:Nipecotic Acids; D010880:Piperidines; C099337:6-(trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid; C011353:siastatin; D005966:Glucuronidase