title: Effects of mandibular nerve block on heat- or cold-induced changes in pulpal blood flow in man.
abstract: Laser Doppler flowmetry (LDF) was used to study the effect of mandibular nerve block, using 3% mepivacain, on heat- or cold-induced changes in pulpal blood flow (PBF) evoked by application of cold or heat to the lingual surfaces of teeth 33 and 43 in nine young subjects. PBF on average showed a 7% increase in response to heat (48 degrees C) and a 20% decrease when exposed to cold (3 degrees C). Neither response was affected by mandibular block. From this we concluded that the effects on PBF of the presently applied heating and cooling of the tooth were solely due to direct thermal influences on the blood vessels, without involvement of vasomotor or sensory nerves.
authors.affiliation: Department of Periodontics, University of Oslo, Norway.
authors.forename: A
authors.initials: A
authors.lastname: Mavropoulos
authors.forename: U
authors.initials: U
authors.lastname: Endal
authors.forename: H
authors.initials: H
authors.lastname: Aars
authors.forename: P
authors.initials: P
authors.lastname: Brodin
mesh_terms: D000328:Adult; D000766:Anesthesia, Dental / Q000379:methods*; D003080:Cold Temperature; D003782:Dental Pulp / Q000098:blood supply* / Q000294:innervation; D003791:Dental Pulp Test; D005260:Female; D006358:Hot Temperature; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008340:Mandibular Nerve / Q000502:physiology*; D008619:Mepivacaine; D008833:Microcirculation; D009407:Nerve Block; D012039:Regional Blood Flow; D014666:Vasomotor System / Q000502:physiology
chemical_list: D008619:Mepivacaine