title: FTY720, a novel immunosuppressant possessing unique mechanisms. II. Long-term graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporine A.
authors.affiliation: Research Laboratories, Yoshitomi Pharmaceutical Industries, Ltd, Saitama, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hoshino
authors.forename: C
authors.initials: C
authors.lastname: Suzuki
authors.forename: M
authors.initials: M
authors.lastname: Ohtsuki
authors.forename: Y
authors.initials: Y
authors.lastname: Masubuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Amano
authors.forename: K
authors.initials: K
authors.lastname: Chiba
mesh_terms: D000818:Animals; D016572:Cyclosporine / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D000068876:Fingolimod Hydrochloride; D005434:Flow Cytometry; D006085:Graft Survival / Q000187:drug effects*; D016027:Heart Transplantation / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D008297:Male; D011409:Propylene Glycols / Q000627:therapeutic use*; D051381:Rats; D011912:Rats, Inbred ACI; D011919:Rats, Inbred Strains; D013110:Sphingosine / Q000031:analogs & derivatives; D013997:Time Factors; D016042:Transplantation, Heterotopic; D014184:Transplantation, Homologous
chemical_list: D007166:Immunosuppressive Agents; D011409:Propylene Glycols; D016572:Cyclosporine; D000068876:Fingolimod Hydrochloride; D013110:Sphingosine