title: The use of non-uniform deuterium labelling ['NMR-window'] to study the NMR structure of a 21mer RNA hairpin.
abstract: The first synthesis of a non-uniformly deuterium labelled 21mer RNA is reported using our 'NMR-window' concept, showing its unique application in the unambiguous NMR assignment of the non-exchangeable aromatic and sugar protons.
authors.affiliation: Department of Bioorganic Chemistry, Biomedical Center, Uppsala University, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Földesi
authors.forename: S I
authors.initials: SI
authors.lastname: Yamakage
authors.forename: F P
authors.initials: FP
authors.lastname: Nilsson
authors.forename: T V
authors.initials: TV
authors.lastname: Maltseva
authors.forename: J
authors.initials: J
authors.lastname: Chattopadhyaya
mesh_terms: D003903:Deuterium; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009690:Nucleic Acid Conformation; D009843:Oligoribonucleotides / Q000737:chemistry*
chemical_list: D009843:Oligoribonucleotides; D003903:Deuterium