A polymerase chain reaction-based test for spinal and bulbar muscular atrophy.
A novel type of genetic alteration, trinucleotide repeat amplification, is responsible for spinal and bulbar muscular atrophy.
Wang
Z
Z
Division of Laboratory Genetics, Mayo Clinic Rochester, MN 55905 USA.
Thibodeau
S N
SN
D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D008526:Medulla Oblongata; D016472:Motor Neuron Disease / Q000175:diagnosis; D009134:Muscular Atrophy, Spinal / Q000175:diagnosis* / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D012091:Repetitive Sequences, Nucleic Acid