title: Selective lung ventilation during thoracoscopy: effects of insufflation on hemodynamics.
abstract: BACKGROUND
  Positive-pressure insufflation during thoracoscopy has been advocated by some authors to facilitate exposure of the intrathoracic structures by expediting collapse of the lung. We hypothesized that insufflation during thoracoscopy may result in hemodynamic compromise despite selective lung ventilation.
  
  
  METHODS
  After placement of invasive monitoring lines, six adult swine underwent selective lung ventilation and thoracoscopy. Baseline measurements of hemodynamic indices were taken before selective lung ventilation. The right lung then was collapsed; data were obtained at insufflation pressures up to 10 mm Hg and were compared with baseline values using Student's t test.
  
  
  RESULTS
  Cardiac index, mean arterial pressure, and left ventricular stroke work index decreased, whereas pulmonary artery and central venous pressures increased (p < 0.05) at insufflation pressures of 5 mm Hg and greater.
  
  
  CONCLUSIONS
  Positive-pressure insufflation during thoracoscopy resulted in significant hemodynamic compromise despite the use of selective lung ventilation. Conversion to thoracotomy may be an alternative if positive-pressure insufflation is necessary to perform the thoracoscopic procedure.
authors.affiliation: Department of Surgery, West Virginia University School of Medicine, Morgantown 26506, USA.
authors.forename: R C
authors.initials: RC
authors.lastname: Hill
authors.forename: D R
authors.initials: DR
authors.lastname: Jones
authors.forename: R A
authors.initials: RA
authors.lastname: Vance
authors.forename: B
authors.initials: B
authors.lastname: Kalantarian
mesh_terms: D000818:Animals; D006439:Hemodynamics; D007327:Insufflation; D012121:Respiration, Artificial; D013552:Swine; D013906:Thoracoscopy