title: [Tuberculosis in children in Madagascar. 122 cases observed at the Soavinandriana-Antananarivo Hospital Center].
abstract: A group of 122 observations of pediatric tuberculosis has been studied. Nurslings represented 34% of the group, children under 8 years old 75% and only 10% were above 12. The sex ratio was 1,1. In a statistically significant way, tuberculous children were less often immunized by BCG than reference children not infected by tuberculosis. Contact has been traced back to close family in 42% of cases. Weight loss was significant at diagnosis time and after treatment the difference with the reference group disappeared. Extrapulmonary localizations were less frequent with children under 2, pulmonary and extrapulmonary localizations associations could be observed with 14% of children under 2 and with 31% of the whole children developing a proved tuberculosis. The importance of bronchial fibroscopy has been pointed out, for it allowed to detect 30% of abnormalities and to prove the diagnosis of tuberculous in 25% of cases. It is regrettable that the National Tuberculosis Control Programme did not prescribe chemoprophylaxis of contact children in its routine instructions, yet it is well known that child tuberculosis is rarely contagious and is not considered a priority by a programme. Finally, the authors reported that the number of pediatric tuberculosis managed in the country showed an obvious underestimation of the problem and they hope this work would lead to think more frequently of that diagnosis in the future.
authors.affiliation: Centre Hospitalier de Soavinandriana, Antananarivo, Madagascar.
authors.forename: P
authors.initials: P
authors.lastname: Boileau
authors.forename: J
authors.initials: J
authors.lastname: Grill
authors.forename: L
authors.initials: L
authors.lastname: Rabarijaona
authors.forename: M
authors.initials: M
authors.lastname: Andriamparany
authors.forename: P
authors.initials: P
authors.lastname: Guyon
authors.forename: G
authors.initials: G
authors.lastname: Auregan
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D001500:BCG Vaccine; D002648:Child; D002675:Child, Preschool; D016358:Contact Tracing; D005260:Female; D006292:Health Priorities; D006786:Hospitals, Urban; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008270:Madagascar; D008297:Male; D012189:Retrospective Studies; D017678:Sex Distribution; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission
chemical_list: D001500:BCG Vaccine