title: Translocation (1;5)(q32;q35) in CD30+ anaplastic large cell non-Hodgkin lymphona of childhood. A case report.
abstract: The authors studied cytogenetically a case of CD30+ anaplastic large cell non-Hodgkin lymphoma previously diagnosed as malignant histiocytosis and detected a translocation involving chromosomes 1 and 5, t(1;5)(q32:q35). After comparing their findings with those from reports in the literature, they comment about the importance of breakpoint q35 on chromosome 5 and point out the importance of associating morphologic, immunoperoxidase, and cytogenetic findings to confirm the diagnosis of this tumor.
authors.affiliation: Department of Pediatrics, School of Medicine of Riberão Preto, University of São Paulo, Brazil.
authors.forename: L G
authors.initials: LG
authors.lastname: Tone
authors.forename: R
authors.initials: R
authors.lastname: Defavery
authors.forename: C A
authors.initials: CA
authors.lastname: Scrideli
authors.forename: J E
authors.initials: JE
authors.lastname: Bernardes
authors.forename: F M
authors.initials: FM
authors.lastname: Torres
authors.forename: F A
authors.initials: FA
authors.lastname: Soares
authors.forename: L C
authors.initials: LC
authors.lastname: Peres
authors.forename: M H
authors.initials: MH
authors.lastname: Duarte
mesh_terms: D002873:Chromosome Fragility; D002878:Chromosomes, Human, Pair 1; D002895:Chromosomes, Human, Pair 5; D006801:Humans; D007223:Infant; D007621:Karyotyping; D017728:Lymphoma, Large-Cell, Anaplastic / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic