Neonatal Malassezia furfur pustulosis.
BACKGROUND
Papulopustular eruptions of the face in neonates are frequently referred to as neonatal acne or sebaceous miliaria. Our findings suggest that there is an association between this type of eruption and Malassezia furfur infection.


METHODS
Direct examination of pustule smears showed M furfur yeasts in eight of 13 cases involving neonates with erythema and papulopustules of the face, neck, and scalp (mean age at onset, 22 days [range, 7 to 30 days]). The pustules were predominantly neutrophilic. Treatment with 2% ketoconazole cream applied topically twice daily was effective in 1 week.


CONCLUSIONS
Malassezia furfur is frequently associated with a common nonfollicular pustulosis of the newborn, probably improperly termed neonatal acne.
Rapelanoro
R
R
Pediatric Dermatology Unit, Pellegrin Children's Hospital, Bordeaux, France.
Mortureux
P
P
Couprie
B
B
Maleville
J
J
Taïeb
A
A
D000935:Antifungal Agents / Q000627:therapeutic use; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007654:Ketoconazole / Q000627:therapeutic use; D008290:Malassezia / Q000302:isolation & purification*; D008297:Male; D012872:Skin Diseases, Vesiculobullous / Q000382:microbiology*
D000935:Antifungal Agents; D007654:Ketoconazole