title: Tumor necrosis factor as marker for monocyte function in chronic myeloid leukemia.
abstract: The intactness of monocyte function in chronic myeloid leukemia (CML) patients as assessed by their ability to secret tumor necrosis factor was evaluated. Monocytes from CML patients continued to respond to lipopolysaccharide (LPS) stimulation even during the refractory period, suggesting different pathways for stimulation by LPS and malignant processes.
authors.affiliation: Division of Laboratory Medicine, Tata Memorial Hospital, Bombay, India.
authors.forename: V S
authors.initials: VS
authors.lastname: Chitnis
authors.forename: P M
authors.initials: PM
authors.lastname: Parikh
authors.forename: J S
authors.initials: JS
authors.lastname: Nadkarni
authors.forename: V C
authors.initials: VC
authors.lastname: Kulkarni
authors.forename: S H
authors.initials: SH
authors.lastname: Advani
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism; D006801:Humans; D007109:Immunity; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000378:metabolism*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000378:metabolism*; D008070:Lipopolysaccharides / Q000494:pharmacology; D008875:Middle Aged; D009000:Monocytes / Q000502:physiology*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D008070:Lipopolysaccharides; D014409:Tumor Necrosis Factor-alpha