Complex cytogenetic rearrangement in a case of unicameral bone cyst.
Cytogenetic analysis of a unicameral bone cyst surgically resected in an 11-year-old boy revealed a highly complex clonal structural rearrangement involving chromosomes 4, 6, 8, 16, 21, and both 12. These findings reinforce the need for further studies on unicameral bone cysts to verify the frequency and to understand the significance of chromosome anomalies in this type of lesion.
Vayego
S A
SA
Department of Biology, São José do Rio Preto, Brazil.
De Conti
O J
OJ
Varella-Garcia
M
M
D001845:Bone Cysts / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D002648:Child; D002869:Chromosome Aberrations; D002873:Chromosome Fragility; D002881:Chromosomes, Human, Pair 12; D002885:Chromosomes, Human, Pair 16; D002891:Chromosomes, Human, Pair 21; D002894:Chromosomes, Human, Pair 4; D002896:Chromosomes, Human, Pair 6; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D007621:Karyotyping; D008297:Male; D014178:Translocation, Genetic