"Early" cancer of the larynx: the concept as defined by clinicians, pathologists, and biologists.
Since a great deal of confusion surrounds the different uses made by clinicians, pathologists, and biologists of the term, this paper clarifies the concept of "early" cancer of the larynx. Clinically, this is usually a glottic neoplasm in which full cordal mobility is still present; early supraglottic cancer is infrequent, and usually a chance finding. Whatever the site, early laryngeal cancer is a minimally invasive neoplastic lesion that does not invade the muscle or cartilage, but is still capable of metastasis. Being confined to the lamina propria, it is more than a carcinoma in situ but less than a deeply infiltrating carcinoma. Superficial extending carcinoma is therefore an early cancer. Biologically, early cancer belongs to stage II.
Ferlito
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A
Department of Otolaryngology, University of Padua, Italy.
Carbone
A
A
Rinaldo
A
A
Ferlito
A
A
DeSanto
L W
LW
D'Angelo
L
L
Barnes
L
L
Devaney
K O
KO
D002278:Carcinoma in Situ / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D005931:Glottis / Q000473:pathology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D009626:Terminology as Topic; D014827:Vocal Cords / Q000473:pathology