Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation.
Markees
T G
TG
Diabetes Division, University of Massachusetts Medical School, Worchester 01605, USA.
Appel
M C
MC
Noelle
R J
RJ
Mordes
J P
JP
Greiner
D L
DL
Rossini
A A
AA
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D019013:CD40 Antigens; D023201:CD40 Ligand; D003921:Diabetes Mellitus, Experimental / Q000601:surgery*; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D007165:Immunosuppression Therapy / Q000379:methods*; D016381:Islets of Langerhans Transplantation / Q000276:immunology*; D017710:Lymphocyte Transfusion; D008562:Membrane Glycoproteins / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D051381:Rats; D011917:Rats, Inbred Lew; D016038:Skin Transplantation / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000276:immunology*
D000911:Antibodies, Monoclonal; D019013:CD40 Antigens; D008562:Membrane Glycoproteins; D023201:CD40 Ligand