Multifocal motor neuropathy with conduction block and Campylobacter jejuni.
We describe a patient with acute multifocal motor neuropathy with conduction block (MMNCB) and high titers of immunoglobulin G anti-GM1 antibodies after Campylobacter jejuni enteritis. Treatment with intravenous immune globulin led to rapid improvement with return of normal function by 6 weeks. This is the first report of C. jejuni enteritis preceding MMNCB.
White
J R
JR
Department of Clinical Neurosciences, Brown University School of Medicine, Providence, RI 02903, USA.
Sachs
G M
GM
Gilchrist
J M
JM
D001323:Autoantibodies / Q000097:blood; D002169:Campylobacter Infections / Q000276:immunology / Q000503:physiopathology*; D016123:Campylobacter jejuni / Q000302:isolation & purification; D005243:Feces / Q000382:microbiology; D005500:Follow-Up Studies; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000150:complications* / Q000503:physiopathology* / Q000628:therapy; D009046:Motor Neurons / Q000502:physiology; D009431:Neural Conduction; D014459:Ulnar Nerve / Q000503:physiopathology
D001323:Autoantibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D016756:Immunoglobulins, Intravenous