A novel reciprocal translocation (14;15)(q11;q24) in a congenital mesoblastic nephroma.
We describe a novel reciprocal translocation, t(14;15)(q11;q24), as the sole cytogenetic aberration in a congenital mesoblastic nephroma. The tumor was predominantly of "classic" morphology, but with small cellular islands of larger cells indicating early transformation to the cellular type. This is the first report of a reciprocal translocation as the sole anomaly in a congenital mesoblastic nephroma.
Sawyer
J R
JR
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, USA.
Miller
J P
JP
Roloson
G J
GJ
D002871:Chromosome Banding; D002883:Chromosomes, Human, Pair 14; D002884:Chromosomes, Human, Pair 15; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000151:congenital / Q000235:genetics* / Q000473:pathology; D018201:Nephroma, Mesoblastic / Q000151:congenital / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic