The evaluation of clastogenic potential of trichloroacetic acid (TCA) in chick in vivo test system.
The objective of the present study was to evaluate the genotoxic potential of trichloroacetic acid (TCA) in chick bone marrow chromosomes, and the experiment was designed to study the dose, route, time and acute vs. sub-acute (fractionated) yield effects of the chemical. TCA induced chromosomal aberrations in a dose, route and time response manner. The results revealed the genotoxic property of TCA in the tested system.
Bhunya
S P
SP
Laboratory of Genetic Toxicology and Wildlife Genetics P.G. Department of Zoology, Utkal University, Orissa, India.
Jena
G B
GB
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D002645:Chickens / Q000235:genetics; D002869:Chromosome Aberrations; D005260:Female; D008297:Male; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D014238:Trichloroacetic Acid / Q000633:toxicity*
D009153:Mutagens; D014238:Trichloroacetic Acid