Cotranscription of two RNA coding for the cell adhesion regulator and its variant in Reh leukemia cells.
Human genomic DNA analysis reveals the existence of polymorphisms at the cell molecular adhesion regulator (CMAR) locus. In order to choose between the two possible open frames deduced from the variant sequence, we have sequence both the human 5' non-coding region and the mouse CMAR variant DNA. We found that both mRNA species coexist in human cells.
Molla
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LEDAC / CNRS URA 1815, Institut Albert Bonniot, Faculté de Medicine, La Tronche, France.
Rouard-Talbot
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MR
D000074183:ATPases Associated with Diverse Cellular Activities; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015815:Cell Adhesion Molecules / Q000737:chemistry / Q000235:genetics*; D003001:Cloning, Molecular; D017931:DNA Primers; D006801:Humans; D007938:Leukemia / Q000235:genetics*; D008666:Metalloendopeptidases; D051379:Mice; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics; D012333:RNA, Messenger / Q000737:chemistry / Q000235:genetics*; D017422:Sequence Analysis, DNA; D014158:Transcription, Genetic; D014407:Tumor Cells, Cultured
D015815:Cell Adhesion Molecules; C490192:Cmar protein, mouse; D017931:DNA Primers; D012333:RNA, Messenger; D008666:Metalloendopeptidases; C112889:SPG7 protein, human; D000074183:ATPases Associated with Diverse Cellular Activities