title: Identification of the telomeres on Schistosoma mansoni chromosomes by FISH.
abstract: The telomeres (molecular termini) of chromosomes play an important role in maintaining the structural integrity of the chromosome. Using a deoxyoligomer that contains the core sequence TTAGGG, we identified by fluorescence in situ hybridization (FISH) the telomeres on all 8 pairs of Schistosoma mansoni mitotic metaphase chromosomes. Our results indicate that S. mansoni exhibits a telomere sequence typical of other species.
authors.affiliation: Department of Microbiology, School of Medicine, State University of New York at Buffalo 14214, USA.
authors.forename: H
authors.initials: H
authors.lastname: Hirai
authors.forename: P T
authors.initials: PT
authors.lastname: LoVerde
mesh_terms: D000818:Animals; D001483:Base Sequence; D015342:DNA Probes / Q000737:chemistry; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D012550:Schistosoma mansoni / Q000235:genetics* / Q000648:ultrastructure; D016615:Telomere / Q000235:genetics*
chemical_list: D015342:DNA Probes