title: Subgingival irrigation effects of chlorhexidine or sanguinarine on gingivitis in orthodontic patients.
abstract: This clinical investigation examined the effect of a single subgingival irrigation of chlorhexidine 0.2% or sanguinarine on gingivitis affecting orthodontically banded first molars in adolescent patients. Eighteen patients with gingivitis participated in the study. Probing depth, papilla bleeding index and plaque index were recorded at four sites for three molars at baseline, 2 weeks and 4 weeks by one investigator. A second investigator irrigated a single application of 3 ml of either chlorhexidine, sanguinarine or saline. The gingival bleeding as determined by papilla bleeding index was almost eliminated in the 4 week period. A reduction of the plaque index and probing depth was observed in all three groups. A significant difference related to probing depth between the effect of saline and chlorhexidine (p<0.01) was noted.
authors.affiliation: Division of Periodontics, King Saud University, College of Dentistry, Riyadh, Saudia Arabia.
authors.forename: N
authors.initials: N
authors.lastname: Babay
authors.forename: N
authors.initials: N
authors.lastname: Al Jasser
mesh_terms: D000293:Adolescent; D000470:Alkaloids / Q000008:administration & dosage / Q000627:therapeutic use*; D000704:Analysis of Variance; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D053119:Benzophenanthridines; D002648:Child; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003773:Dental Plaque / Q000150:complications / Q000188:drug therapy / Q000209:etiology; D003774:Dental Plaque Index; D005884:Gingival Hemorrhage / Q000188:drug therapy; D005891:Gingivitis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007546:Isoquinolines; D008963:Molar; D009067:Mouthwashes / Q000627:therapeutic use*; D015999:Multivariate Analysis; D009967:Orthodontic Appliances / Q000009:adverse effects*; D010512:Periodontal Index; D016037:Single-Blind Method; D012965:Sodium Chloride / Q000627:therapeutic use; D007507:Therapeutic Irrigation / Q000379:methods
chemical_list: D000470:Alkaloids; D000891:Anti-Infective Agents, Local; D053119:Benzophenanthridines; D007546:Isoquinolines; D009067:Mouthwashes; D012965:Sodium Chloride; C005705:sanguinarine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine