Perioperative treatment with phosphatidic acid inhibitor (Lisofylline leads to prolonged survival of hearts in the guinea pig to rat xenotransplant model.
Valdivia
L A
LA
Pittsburgh Transplantation Institute, University of Pittsburgh Medical Center, Pennsylvania 15213, USA.
Murase
N
N
Rao
A S
AS
Rice
G
G
Singer
J W
JW
Sun
H
H
Todo
S
S
Pan
F
F
Subbotin
V
V
Fung
J J
JJ
Starzl
T E
TE
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D000910:Antibodies, Heterophile / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D006085:Graft Survival / Q000187:drug effects* / Q000276:immunology; D006168:Guinea Pigs; D016027:Heart Transplantation / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007432:Intraoperative Period; D008775:Methylprednisolone / Q000627:therapeutic use; D010431:Pentoxifylline / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010712:Phosphatidic Acids / Q000037:antagonists & inhibitors; D051381:Rats; D011917:Rats, Inbred Lew; D014183:Transplantation, Heterologous / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000910:Antibodies, Heterophile; D003176:Complement C3; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D010712:Phosphatidic Acids; C025189:lisofylline; D010431:Pentoxifylline; D008775:Methylprednisolone