title: Prediction of 3-year outcome of treated alcoholics by an empirically derived multivariate typology.
abstract: OBJECTIVE
  This study examined whether an empirically derived multivariate typology can predict outcome in treated alcoholics.
  
  
  METHODS
  Two hundred fifty-nine hospitalized male alcoholics were divided into two subtypes by means of cluster analysis of clinical factors. Type A showed the features of sporadic late-onset alcoholism, whereas type B manifested the characteristics of familial early-onset alcoholism. The prospective 3-year outcomes in the two subtypes were compared.
  
  
  RESULTS
  The follow-up rate was 83%. The mortality and abstinence rates for type A patients (N = 98) were 15.3% and 32.7%, respectively, and for type B patients (N = 116), 23.3% and 18.1%, respectively. The age-corrected relative mortality risk and relative abstinence rate for type A patients compared with type B patients were 0.59 and 1.60, respectively.
  
  
  CONCLUSIONS
  Familial early-onset alcoholism has a poor outcome in Japan, and this multivariate typology has high predictive validity.
authors.affiliation: Komagino Hospital, Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Yoshino
authors.forename: M
authors.initials: M
authors.lastname: Kato
mesh_terms: D000328:Adult; D017668:Age of Onset; D000437:Alcoholism / Q000145:classification* / Q000235:genetics / Q000534:rehabilitation*; D016000:Cluster Analysis; D005190:Family; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011336:Probability; D015203:Reproducibility of Results; D013695:Temperance; D016896:Treatment Outcome