title: Magnetic resonance imaging in potential postsurgical recurrence of breast cancer: pitfalls and limitations.
abstract: OBJECTIVE
  To determine the sensitivity and specificity of magnetic resonance imaging (MRI) of the breast for detecting recurrent carcinoma.
  
  
  METHODS
  Thirteen patients ranging in age from 47 to 77 years who had undergone lumpectomy 5 months to 8 years earlier and who had mammographic findings suggestive of recurrence underwent contrast-enhanced dynamic MRI. Histologic confirmation was obtained in all cases.
  
  
  RESULTS
  Of the eight lesions (in seven patients) for which biopsy proved recurrence, MRI correctly identified six; there were two false negative results. Of the six benign lesions, four were correctly identified by MRI. The two false positive results involved fat necrosis and a foreign-body reaction respectively.
  
  
  CONCLUSIONS
  These results confirm previous reports of the poor specificity of MRI of focal breast lesions. The authors therefore recommend caution in the use of breast MRI in the assessment and management of suspected recurrent carcinoma.
authors.affiliation: Department of Radiology, Mount Sinai Hospital, Toronto, Ontario.
authors.forename: E K
authors.initials: EK
authors.lastname: Cohen
authors.forename: C M
authors.initials: CM
authors.lastname: Leonhardt
authors.forename: R S
authors.initials: RS
authors.lastname: Shumak
authors.forename: I C
authors.initials: IC
authors.lastname: Soutar
authors.forename: K
authors.initials: K
authors.lastname: Bukhanov
authors.forename: E K
authors.initials: EK
authors.lastname: Fishell
authors.forename: D B
authors.initials: DB
authors.lastname: Plewes
mesh_terms: D000368:Aged; D001706:Biopsy; D001941:Breast Diseases / Q000175:diagnosis; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002277:Carcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003287:Contrast Media; D005188:False Negative Reactions; D005189:False Positive Reactions; D005218:Fat Necrosis / Q000175:diagnosis; D005260:Female; D005549:Foreign-Body Reaction / Q000175:diagnosis; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008327:Mammography; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA