title: [Tuberculosis in the prison milieu at Antananarivo from 1990 to 1993].
abstract: Within 42 months, from June 1990 to December 1993, 454 cases of tuberculosis have been recorded in the central remand home of Antananarivo. The tubercular prevalence observed was there eight times superior to that of the global population of Madagascar. Among the 360 pulmonary tuberculosis, only one did not have any bacteriological proof; among the 94 extrapulmonary tuberculosis, 37 have been proved by histology or bacteriology. Among the extrapulmonary tuberculosis, pleurisies were obviously preeminent (79/94). Association of tubercular localizations could be observed with 21% of the patients. New cases of smear-positive pulmonary tuberculosis (PMT+) represented 81% of all the PMT+, recurrences were 9% and revivals 10%. Since February 1991, the 8 months short course regimen was the standard applied; before, the lack of stock did not allowed any standardization. The PMT+ new cases recovery rate increased from 42.5% in 1990 to 74% in 1993, whereas lethality decreased from 23% in 1990 to 8% in 1993. Patient dropouts were noted only with released or escaped individuals. Treatment failure rate was 4%. The diminution of cases despite the constancy of prisoners number and the carrying out of activities by the same health team make questionable the explanatory factors of the burst of tuberculosis-diseases in a prison milieu. Because of the importance of prison tubercular foci in terms of public health and the satisfactory results obtained, the Programme proposes to apply the model of partnership developed between the Tonga soa NGO and the prison administration to other prisons in Madagascar.
authors.affiliation: Institut d'Hygiène Sociale, Service Tuberculose-Lèpre, Antananarivo, Madagascar.
authors.forename: G
authors.initials: G
authors.lastname: Auregan
authors.forename: F
authors.initials: F
authors.lastname: Rakotomanana
authors.forename: M
authors.initials: M
authors.lastname: Ratsitorahina
authors.forename: N
authors.initials: N
authors.lastname: Rakotoniaina
authors.forename: O
authors.initials: O
authors.lastname: Rabemananjara
authors.forename: R
authors.initials: R
authors.lastname: Raharimanana
authors.forename: P
authors.initials: P
authors.lastname: Boisier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008270:Madagascar; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D010352:Patient Dropouts; D011159:Population Surveillance; D015995:Prevalence; D011330:Prisons; D017211:Treatment Failure; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy; D014504:Urban Health