Canadian patient played key role in uncovering secrets about early-onset Alzheimer's disease.
Last June, the University of Toronto announced that Canadian scientists and a team of international researchers had discovered the gene responsible for most cases of early-onset Alzheimer's disease. One of the key players in that discovery had died just 3 months earlier. Frances Hodge, who participated in a battery of tests for the 20 years she lived with the disease, helped lead researchers to gene S182--and an ember of hope for future generations.
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D000368:Aged; D000544:Alzheimer Disease / Q000235:genetics* / Q000503:physiopathology / Q000523:psychology; D002883:Chromosomes, Human, Pair 14 / Q000235:genetics*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009154:Mutation / Q000235:genetics; D009864:Ontario