title: [Preoperative differential diagnosis of cystic adnexal tumors: double-contrast MRT].
abstract: OBJECTIVE
  Preoperative assessment of adnexal lesions as benign or malignant by MRI with gastrointestinal and intravenous contrast.
  
  
  METHODS
  46 patients with benign (n = 42) and malignant (n = 4) cystic adnexal tumours underwent MRI of the pelvis. Transaxial and coronal images were acquired using conventional T1- and T2-weighted SE-sequences after oral administration of superparamagnetic iron oxide particles (Ferristene). Additional T1-weighted SE-images were obtained immediately following gadodiamide (Gd DTPA-BMA) injection.
  
  
  RESULTS
  MRI correctly classified the four malignant lesions, whereas nine histologically benign lesions were misdiagnosed as malignant. Intravenous contrast yielded a superior delineation of intratumor architecture.
  
  
  CONCLUSIONS
  Due to exclusion of solid structures. MRI with oral and i.v. contrast enables to dismiss suspected malignity in cystic adnexal lesions. Because of the non-specificity of the macroscopic criteria of dignity, the MR diagnosis "malignity" is of limited value.
authors.affiliation: Klinik für Radiologische Diagnostik, Christian-Albrachts-Universität zu Kiel.
authors.forename: M
authors.initials: M
authors.lastname: Reuter
authors.forename: J C
authors.initials: JC
authors.lastname: Steffens
authors.forename: U
authors.initials: U
authors.lastname: Schüppler
authors.forename: C
authors.initials: C
authors.lastname: Muhle
authors.forename: G
authors.initials: G
authors.lastname: Brinkmann
authors.forename: A
authors.initials: A
authors.lastname: Kohl
authors.forename: D
authors.initials: D
authors.lastname: Weisner
authors.forename: J
authors.initials: J
authors.lastname: Lüttges
authors.forename: R P
authors.initials: RP
authors.lastname: Spielmann
authors.forename: M
authors.initials: M
authors.lastname: Heller
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D003536:Cystadenocarcinoma / Q000175:diagnosis / Q000473:pathology; D003537:Cystadenoma / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009942:Organometallic Compounds; D010048:Ovarian Cysts / Q000175:diagnosis / Q000473:pathology; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010053:Ovary / Q000473:pathology; D004369:Pentetic Acid / Q000031:analogs & derivatives; D011300:Preoperative Care
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; C064925:gadodiamide; D005682:Gadolinium; D019786:Gadolinium DTPA