title: Cardiac output response to dynamic exercise after atrial switch repair for transposition of the great arteries.
abstract: Results from this study showed that patients who underwent successful operation for transposition of the great arteries had no appropriate increase in stroke volume in response to exercise of a nature similar to common recreational activities. The impairment, most likely due to disturbances in both venous return and ventricular systolic function, is compensated for by an increase in peripheral oxygen extraction; however, this increase may not be adequate with maturation or during prolonged exercise when cardiovascular constraints are more important.
authors.affiliation: Laboratorie de Physiopathologie de l'Exercise, Grenoble, France.
authors.forename: E
authors.initials: E
authors.lastname: Page
authors.forename: H
authors.initials: H
authors.lastname: Perrault
authors.forename: P
authors.initials: P
authors.lastname: Flore
authors.forename: A M
authors.initials: AM
authors.lastname: Rossignol
authors.forename: S
authors.initials: S
authors.lastname: Pironneau
authors.forename: C
authors.initials: C
authors.lastname: Rocca
authors.forename: B
authors.initials: B
authors.lastname: Aguilaniu
mesh_terms: D002302:Cardiac Output; D002648:Child; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D010101:Oxygen Consumption; D011184:Postoperative Period; D013318:Stroke Volume; D014188:Transposition of Great Vessels / Q000503:physiopathology / Q000601:surgery*