Pyoderma gangrenosum in a patient with cryoglobulinemia and hepatitis C successfully treated with interferon alfa.
We describe a patient with long-standing pyoderma gangrenosum unresponsive to therapy. The patient had concomitant cryoglobulinemia and hepatitis C. When the hepatitis C was treated with interferon alfa-2a his pyoderma gangrenosum resolved. Whether this was from the interferon alfa or spontaneous resolution is not known.
Smith
J B
JB
Division of Dermatology, University of South Florida College of Medicine, Tampa 33612-4799, USA.
Shenefelt
P D
PD
Soto
O
O
Valeriano
J
J
D000328:Adult; D003449:Cryoglobulinemia / Q000150:complications*; D006526:Hepatitis C / Q000150:complications* / Q000628:therapy; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D017511:Pyoderma Gangrenosum / Q000150:complications / Q000473:pathology / Q000628:therapy*; D011994:Recombinant Proteins
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins