title: Chromonyl-aminosalicylic acid derivatives as possible antimycobacterial agents.
abstract: N-(2H,3H,4H-4-oxo-6-R1-2-R2O-benzopyran-3-ylidenmethyl) derivatives and imino derivatives of 3-, 4-, 5-aminosalicylic acids were prepared. It was found that some of the synthesized derivatives of 4-aminosalicylic acid are as effective against typical and atypical strains of mycobacteria as isoniazid (INH). Interesting activity of some derivatives against yeast was also found.
authors.affiliation: Department of Organic Chemistry, Comenius University, Bratislava, Slovakia.
authors.forename: M
authors.initials: M
authors.lastname: Lácová
authors.forename: H
authors.initials: H
authors.lastname: Stankovicová
authors.forename: Z
authors.initials: Z
authors.lastname: Odlerová
mesh_terms: D000636:Aminosalicylic Acids / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D009161:Mycobacterium / Q000187:drug effects*
chemical_list: D000636:Aminosalicylic Acids; D000900:Anti-Bacterial Agents