title: Colitis cystica profunda: imaging diagnosis and conservative treatment: report of two cases.
abstract: Rectally localized colitis cystica profunda can simulate mucosecretory carcinoma.
  
  
  OBJECTIVE
  Because endoscopic examination and barium enema do not clarify the diagnosis, other diagnostic imaging methods such as transrectal ultrasonography, computerized tomography, or magnetic resonance imaging are needed.
  
  
  RESULTS
  Transrectal ultrasonography identifies multiple cysts in the rectal submucosa, with areas of echorefringent fibrosis between cysts, and confirms the absence of lymph node involvement or invasion of the muscular layer. Findings with computerized tomography and magnetic resonance imaging have not previously been described for colitis cystica profunda. With computerized tomography, the lesion appears as a noninfiltrating entity in the submucosa, with loss of perirectal layers of fatty tissue and thickening of the levator ani muscle. With nuclear magnetic imaging, nodulations produce intense signals that increase in T2, illustrating the mucoprotein content of the cysts. The presence in surgical biopsy material of large, whole cysts confirms the diagnosis.
  
  
  CONCLUSIONS
  Reeducation of bowel habits aimed at avoiding straining and a high-fiber diet together with bulk laxatives can lead to complete remission of lesions in 6 to 18 months.
authors.affiliation: Department of Medicine, School of Medicine, University of Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Valenzuela
authors.forename: J L
authors.initials: JL
authors.lastname: Martín-Ruiz
authors.forename: E
authors.initials: E
authors.lastname: Alvarez-Cienfuegos
authors.forename: A M
authors.initials: AM
authors.lastname: Caballero
authors.forename: F
authors.initials: F
authors.lastname: Gallego
authors.forename: I
authors.initials: I
authors.lastname: Carmona
authors.forename: M
authors.initials: M
authors.lastname: Rodríguez-Téllez
mesh_terms: D000328:Adult; D003092:Colitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography