title: A case of vulvar schwannoma.
abstract: Schwannoma is generally a solitary, nodular, benign tumor of a peripheral nerve sheath, and it rarely affects the external female genitalia. Its most-common locations are the head, neck, upper and lower extremities, posterior mediastinum, and retroperitoneum. We treated a 29-year-old woman with a vulvar schwannoma. A tumor of 2.5 cm in diameter was resected for treatment and biopsy. It was a capsulate tumor with a smooth surface, and was elastic in consistency. A histological examination revealed a swirling pattern with some palisading of spindle-shaped cells in H.E. stains. Immunohistochemical studies showed the tumor to be positive for S-100 protein and negative for desmin. As a result, the mass proved to be schwannoma originating from the vulva.
authors.affiliation: Department of Obstetrics and Gynecology, Osaka Medical College, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: T
authors.initials: T
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Ueki
authors.forename: M
authors.initials: M
authors.lastname: Ueki
authors.forename: O
authors.initials: O
authors.lastname: Sugimoto
mesh_terms: D000328:Adult; D003893:Desmin / Q000032:analysis; D005260:Female; D006801:Humans; D009442:Neurilemmoma / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis; D014846:Vulvar Neoplasms / Q000473:pathology*
chemical_list: D003893:Desmin; D009418:S100 Proteins