title: A randomized study comparing suture with non-suture cold-knife conization.
abstract: OBJECTIVE
  To compare the short-term outcome of cold-knife conization between suture and non-suture (with Monsel's solution pack) methods.
  
  
  METHODS
  Between February, 1990 and March, 1992, 142 patients underwent cold-knife conization were randomly allocated into 2 groups. The hemostasis was done by suture in one group and by Monsel's solution pack without suture in the other group. The patients' and cone specimens' characteristics as well as short-term outcome were recorded and compared using Chi-square test, Fisher exact test and t-test where appropriate.
  
  
  RESULTS
  The patients' characteristics, cone size, and histologic diagnosis of both groups were comparable. The non-suture group had shorter operative time (10.69 +/- 7.86 vs. 20.04 +/- 6.99 minutes) and lesser late hemorrhage (2.9 vs. 15.9%) than the suture group (p < 0.05). There was no statistical difference in the operative blood loss.
  
  
  CONCLUSIONS
  The non-suture method of conization should replace the traditional suture method.
authors.affiliation: Department of Obstetrics and Gynecoloty, Faculty of Medecine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Tangtrakul
authors.forename: S
authors.initials: S
authors.lastname: Srisupundit
authors.forename: V
authors.initials: V
authors.lastname: Linasmita
authors.forename: S
authors.initials: S
authors.lastname: Bullangpoti
authors.forename: N
authors.initials: N
authors.lastname: Israngura
authors.forename: S
authors.initials: S
authors.lastname: Wilailak
authors.forename: O
authors.initials: O
authors.lastname: Panijayanusondthi
mesh_terms: D000328:Adult; D000368:Aged; D019092:Conization / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013537:Sutures; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000601:surgery*