Pilomatricoma-like endometrioid adenosquamous carcinoma of the ovary with neuroendocrine differentiation.
A case of high-grade endometrioid adenosquamous carcinoma of the ovary showing pilomatricoma-like areas and neuroendocrine differentiation is presented. The pilomatricoma-like areas were strongly positive for cytokeratin and vimentin, whereas the poorly differentiated areas of the tumor were positive for cytokeratin, synaptophysin, and neuron-specific enolase. Review of the literature did not show any published report of adenosquamous carcinoma with pilomatricoma-like areas either in the ovary or in the uterus.
Fang
J
J
Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA.
Keh
P
P
Katz
L
L
Rao
M S
MS
D018196:Carcinoma, Adenosquamous / Q000473:pathology*; D018269:Carcinoma, Endometrioid / Q000473:pathology*; D002454:Cell Differentiation; D005260:Female; D006801:Humans; D008875:Middle Aged; D009490:Neurosecretory Systems / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D018296:Pilomatrixoma / Q000473:pathology*