title: Synthesis and post-coital contraceptive activity of ether and ester analogues of 2,3-diaryl-2H-1-benzopyrans.
abstract: Ether and ester analogues of 2,3-diaryl-2H-1-benzopyrans have been synthesised and tested for their pregnancy inhibiting activity in immature rats. Some of the compounds exhibit potent activity. Structure-activity relationship relative to the hydroxy analogue has been discussed. In general, esters were found to be better inhibitory agents.
authors.affiliation: Regional Research Laboratory, Jammu Tawi, India.
authors.forename: K
authors.initials: K
authors.lastname: Hajela
authors.forename: K K
authors.initials: KK
authors.lastname: Kapoor
authors.forename: R S
authors.initials: RS
authors.lastname: Kapil
mesh_terms: D000818:Animals; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D003283:Contraceptives, Postcoital, Synthetic / Q000138:chemical synthesis* / Q000494:pharmacology; D005260:Female; D008297:Male; D011247:Pregnancy; D051381:Rats; D013329:Structure-Activity Relationship
chemical_list: D001578:Benzopyrans; D003283:Contraceptives, Postcoital, Synthetic