title: Osteoporosis and its relationship to oral bone loss.
abstract: Osteoporosis, an age-related condition, is classified into primary and secondary types. Primary osteoporosis encompasses the postmenopausal and senile types; secondary osteoporosis occurs "secondary" to endocrine and renal diseases. Subjects affected by osteoporosis have an overall reduced bone mass and become highly susceptible to bone fractures. Dual energy x-ray absorptiometry is the method most often used to determine the risk for osteoporotic fractures. In the past decade, a number of studies have suggested a possible correlation between systemic osteoporosis and alveolar bone loss in periodontal disease pathogenesis. It appears that a clear correlation between periodontal health and the general mineral status of the skeleton is still lacking. This review addresses the pathogenesis of osteoporosis and emphasizes the multifactorial nature of bone loss. The current concepts in alveolar bone loss resulting from osteoporosis and its implications as a risk factor in periodontal disease development are also presented.
authors.affiliation: State University of New York, Buffalo, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Loza
authors.forename: L C
authors.initials: LC
authors.lastname: Carpio
authors.forename: R
authors.initials: R
authors.lastname: Dziak
mesh_terms: D000368:Aged; D016301:Alveolar Bone Loss / Q000209:etiology* / Q000503:physiopathology; D002117:Calcitriol / Q000502:physiology; D016207:Cytokines / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications* / Q000209:etiology / Q000235:genetics; D015663:Osteoporosis, Postmenopausal / Q000150:complications; D016388:Tooth Loss / Q000209:etiology
chemical_list: D016207:Cytokines; D002117:Calcitriol