title: [The diagnostic significance of blast immunophenotype assay in patients with acute leukemia].
abstract: A detailed analysis of immunophenotypes of 120 adult newly diagnosed patients with acute leukaemias was performed. Using the immunopheno-typing, it was possible to defined 96,7% of leukemia cases. The proportion of leukemia subtypes was: AML in 62,5%, ALL in 32,5%, acute biphenotypic leukaemia 1,7% and acute undifferentiated leukaemia (AUL) in 3,3%. The diagnosis initially made according FAB criterias in 12,5% cases after the immunophenotyping was verified. Above analyses showed the existence of the atypical blasts phenotypes in 31%: co-expression of CD 19, CD2 and CD7 markers in AML, co-expression of CD 33 marker in ALL, co-expression of CD 19 marker in T cell ALL and biphenotypic (mixed-lineage) leukaemia.
authors.affiliation: Kliniki Hematologii Collegium Medicum Uniwersytetu Jagiellońskiego.
authors.forename: B
authors.initials: B
authors.lastname: Piatoska-Jakubas
authors.forename: A
authors.initials: A
authors.lastname: Pituch-Noworolska
authors.forename: A B
authors.initials: AB
authors.lastname: Skotnicki
authors.forename: A
authors.initials: A
authors.lastname: Balana-Nowak
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000145:classification*
chemical_list: D015703:Antigens, CD; D014408:Biomarkers, Tumor