[The morphofunctional changes in the kidneys of patients with staghorn nephrolithiasis operated on using a block of the renal blood flow].
A study was made of morphofunctional changes in the kidneys depending on duration of ischemia and use of the drug combination proposed by the contributors to the article, for pharmacological protection of the kidney. The examination of intraoperative renal biopsy specimens revealed the hystological structure of the kidney to be more intact, with its functional capacity tending to restore more readily than in control, in those patients in whom pharmacological protection had been embarked on. Constricting the renal artery and carrying on pharmacological protection of kidney we succeeded in effecting a complete elimination of the coral-like calculus fragments in favourable conditions on a "dry" organ, being able to manage with almost non-traumatic nephrotomy associated with minimum loss of blood, which fact resulted in the reduction of the lithogenesis recurrence rate by 17 %.
Guzenko
V N
VN
Danil'chenko
S A
SA
Shevchenko
N I
NI
D000818:Animals; D001706:Biopsy; D006801:Humans; D007431:Intraoperative Complications / Q000503:physiopathology / Q000517:prevention & control; D007511:Ischemia / Q000503:physiopathology / Q000517:prevention & control; D007668:Kidney / Q000098:blood supply* / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D007669:Kidney Calculi / Q000503:physiopathology* / Q000601:surgery; D008026:Ligation; D051381:Rats; D017208:Rats, Wistar; D012077:Renal Artery / Q000601:surgery; D013997:Time Factors