FTY720, a novel immunosuppressant possessing unique mechanisms. II. Long-term graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporine A.
Hoshino
Y
Y
Research Laboratories, Yoshitomi Pharmaceutical Industries, Ltd, Saitama, Japan.
Suzuki
C
C
Ohtsuki
M
M
Masubuchi
Y
Y
Amano
Y
Y
Chiba
K
K
D000818:Animals; D016572:Cyclosporine / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D000068876:Fingolimod Hydrochloride; D005434:Flow Cytometry; D006085:Graft Survival / Q000187:drug effects*; D016027:Heart Transplantation / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D008297:Male; D011409:Propylene Glycols / Q000627:therapeutic use*; D051381:Rats; D011912:Rats, Inbred ACI; D011919:Rats, Inbred Strains; D013110:Sphingosine / Q000031:analogs & derivatives; D013997:Time Factors; D016042:Transplantation, Heterotopic; D014184:Transplantation, Homologous
D007166:Immunosuppressive Agents; D011409:Propylene Glycols; D016572:Cyclosporine; D000068876:Fingolimod Hydrochloride; D013110:Sphingosine