title: Intracardiac injection of T-61, a veterinary euthanasia drug.
abstract: We report a suicidal attempt by intracardiac injection of T-61, a veterinary euthanasia drug containing embutramide, mebezonium and tetracaine in dimethylformamide. The main complications were reversible acute renal failure and pericardial effusion. There was a delayed abnormality of the liver function tests possibly related to the dimethylformamide solvent. A liver biopsy on day 16 showed a normal hepatic architecture with lipid-containing lysosomes and prominent vesicular endoplasmic reticulum noted on electron microscopy.
authors.affiliation: Cliniques Universitaires St-Luc, Brussels, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Hantson
authors.forename: C
authors.initials: C
authors.lastname: Semaan
authors.forename: J C
authors.initials: JC
authors.lastname: Jouret
authors.forename: J
authors.initials: J
authors.lastname: Rahier
authors.forename: R
authors.initials: R
authors.lastname: Lauwerys
authors.forename: J P
authors.initials: JP
authors.lastname: Brunain
authors.forename: P
authors.initials: P
authors.lastname: Mahieu
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced; D000328:Adult; D000577:Amides / Q000008:administration & dosage / Q000506:poisoning*; D004338:Drug Combinations; D018870:Endoplasmic Reticulum, Rough / Q000187:drug effects / Q000648:ultrastructure; D006801:Humans; D007267:Injections; D008099:Liver / Q000187:drug effects / Q000473:pathology / Q000648:ultrastructure; D008111:Liver Function Tests; D008247:Lysosomes / Q000187:drug effects / Q000648:ultrastructure; D010490:Pericardial Effusion / Q000139:chemically induced; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage / Q000506:poisoning*; D013406:Suicide, Attempted; D013748:Tetracaine / Q000008:administration & dosage / Q000506:poisoning*; D013997:Time Factors
chemical_list: D000577:Amides; D004338:Drug Combinations; D000644:Quaternary Ammonium Compounds; D013748:Tetracaine; C015591:T 61