Epilepsy in the nevoid basal-cell carcinoma syndrome (Gorlin syndrome): report of a case due to a focal neuronal heterotopia.
We present a case of uncontrolled temporal lobe epilepsy due to a focal left temporal neuronal heterotopia associated with the nevoid-basal-cell carcinoma syndrome. This is the first pathologically described lesion associated with temporal lobe epilepsy in this syndrome. Because the patient's seizures resolved after a modified left anterior temporal lobectomy, this case illustrates that epilepsy in patients with the nevoid basal-cell carcinoma syndrome is potentially curable and should be investigated appropriately.
Hogan
R E
RE
Department of Neurology, The Royal Melbourne Hospital, Melbourne, Australia.
Tress
B
B
Gonzales
M F
MF
King
J O
JO
Cook
M J
MJ
D000293:Adolescent; D001478:Basal Cell Nevus Syndrome / Q000150:complications*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D004833:Epilepsy, Temporal Lobe / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009474:Neurons / Q000473:pathology; D013702:Temporal Lobe / Q000601:surgery; D014057:Tomography, X-Ray Computed