title: [Otologic manifestations presenting and predominating in necrotizing angiitis].
abstract: The authors report on 5 observations of necrotising angiitis with a specifically otological onset, namely 4 Wegener's syndromes and one periarteritis nodosa. In all 5 cases, the initial symptomatology consisted of otological signs in a feverish context, producing pictures of serous or sero-purulent otitis. Its resistance to usual forms of therapy led in 3 cases to the installation of transtympanic aerators, and in 2 cases to the performance of an antro-attico-mastoidectomy. One of the observations led to the discovery in the middle ear of a histological aspect specific to the disease, from which it can be considered that the otologic impairment could be a specific seat of the disease. The 5th observation is particular in that it was the otological signs which revealed each time a new progression of the disease, enabling the immediate implementation of an adapted treatment prior to the occurrence of the systemic signs. 3 observations proved the difficulty of diagnosis at the initial stage, when at times only the otological signs are present, together with the importance of its discovery prior to the occurrence of systemic lesions that are occasionally irreversible. Any isolated otological symptomatology in a feverish context, resisting usual therapies, should evoke the diagnosis, and lead to the performance of further duly adapted examinations (sedimentation rate, pulmonary X-ray, proteinuria, hematuria).
authors.affiliation: Groupe hospitalier Bichat Claude Bernard, Service O.R.L. et Chirurgie Cervico-Faciale, Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Depondt
authors.forename: I
authors.initials: I
authors.lastname: Fligny
authors.forename: P
authors.initials: P
authors.lastname: Leplus
authors.forename: P
authors.initials: P
authors.lastname: Gehanno
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D018450:Disease Progression; D004432:Ear, Middle / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008416:Mastoid / Q000601:surgery; D008875:Middle Aged; D008876:Middle Ear Ventilation; D010034:Otitis Media with Effusion / Q000209:etiology* / Q000601:surgery; D010035:Otitis Media, Suppurative / Q000209:etiology; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000175:diagnosis