title: A cost analysis of autologous and allogeneic transfusions in hip-replacement surgery.
abstract: OBJECTIVE
  To analyze the cost consequences of autologous versus allogeneic transfusions.
  
  
  METHODS
  Costs were determined when allogeneic transfusions were given in addition to, or instead of, autologous transfusions. Hospital charges were used to estimate costs for hip-replacement surgery. The main outcome measure was estimated incremental hospital costs per unit transfused.
  
  
  RESULTS
  Among donors of autologous blood, mean total charges were $7,200 greater for recipients of both autologous and allogeneic transfusions than for recipients of autologous transfusion only (P=0.0001). Each allogeneic transfusion was associated with additional costs of $1,480. In a second cohort of patients receiving identical amounts of either allogeneic or autologous blood (mean=2.3 units), total hospital charges were a mean of $4,800 greater (P=0.0001) for allogeneic recipients. The per unit excess costs associated with each unit of allogeneic blood cohort were $1,043.
  
  
  CONCLUSIONS
  Allogeneic transfusions are associated with incremental hospital costs of about $1,000 to $1,500 per unit transfused when compared with costs for similar patients receiving no transfusions or 1 to 5 units of autologous blood.
authors.affiliation: Department of Pathology, University of Rochester Medical Center, New York, USA.
authors.forename: N
authors.initials: N
authors.lastname: Blumberg
authors.forename: S A
authors.initials: SA
authors.lastname: Kirkley
authors.forename: J M
authors.initials: JM
authors.lastname: Heal
mesh_terms: D000704:Analysis of Variance; D001803:Blood Transfusion / Q000191:economics*; D001804:Blood Transfusion, Autologous / Q000191:economics*; D015331:Cohort Studies; D003362:Cost-Benefit Analysis; D006622:Hip Prosthesis / Q000191:economics*; D017722:Hospital Charges; D006801:Humans; D016014:Linear Models