title: Diabetes complications: why is glucose potentially toxic?
authors.affiliation: Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
authors.forename: D
authors.initials: D
authors.lastname: Porte
authors.forename: M W
authors.initials: MW
authors.lastname: Schwartz
mesh_terms: D000818:Animals; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000201:enzymology; D003921:Diabetes Mellitus, Experimental / Q000150:complications / Q000201:enzymology; D004730:Endothelium, Vascular / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000494:pharmacology* / Q000633:toxicity; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000201:enzymology; D007527:Isoenzymes / Q000037:antagonists & inhibitors* / Q000378:metabolism; D007668:Kidney / Q000201:enzymology; D009131:Muscle, Smooth, Vascular / Q000201:enzymology; D011493:Protein Kinase C / Q000037:antagonists & inhibitors* / Q000378:metabolism; D064546:Protein Kinase C beta; D051381:Rats; D012039:Regional Blood Flow / Q000187:drug effects; D012160:Retina / Q000201:enzymology; D012171:Retinal Vessels / Q000502:physiology
chemical_list: D004791:Enzyme Inhibitors; D007527:Isoenzymes; D011493:Protein Kinase C; D064546:Protein Kinase C beta