Segregation of optic input in a three-eyed mammal.
Using a marsupial mouse, we have transplanted additional eye primordia to the midbrain at stages before host visual centers are normally innervated; transplant or host projections were later traced. In contrast to the normally continuous crossed retinocollicular input, both transplant and host projections were arranged as rostrocaudally aligned stripes or as discrete patches. We propose that competitive interactions between transplant and host axons have induced the discontinuous input.
Dunlop
S A
SA
Department of Zoology, The University of Western Australia, Nedlands 6009, Australia.
Lund
R D
RD
Beazley
L D
LD
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D001369:Axons / Q000502:physiology; D001921:Brain / Q000502:physiology*; D005123:Eye / Q000637:transplantation*; D005260:Female; D051379:Mice; D008815:Mice, Inbred Strains; D014795:Visual Pathways / Q000502:physiology*