Pulmonary sarcoidosis coexisting with systemic lupus erythematosus.
A 23 year old female presented with fatigue, Raynaud's syndrome, symmetric polyarthritis, lymphocytopenia, hypocomplementemia, IgG elevation, and antinuclear antibodies with anti-U1RNP specificity. A diagnosis of systemic lupus erythematosus (SLE) was made. Disseminated micronodular infiltration in the chest X-ray, a pattern of lymphocytic alveolitis by bronchoalveolar lavage, histologic demonstration of non-caseating epitheloid microgranulomas, and rapid reversal of lung disease upon low-dose methylprednisolone treatment led to a diagnosis of concomitant sarcoidosis. Clues to the diagnosis of sarcoidosis coexisting with SLE are discussed.
Schnabel
A
A
Rheumatologische Poliklinik, Medizinische Universität Lübeck, Germany.
Barth
J
J
Schubert
F
F
Gross
W L
WL
D000328:Adult; D016516:CD4-CD8 Ratio; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D011859:Radiography; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging