title: Actinomyces odontolyticus thoracopulmonary infections. Two cases in lung and heart-lung transplant recipients and a review of the literature.
abstract: We present the first case of mediastinitis and the third case of pneumonia attributed to Actinomyces odontolyticus. The first patient presented 10 months after single-lung transplant with a subacute apical infiltrate in the native lung and responded to therapy with oral penicillin. The second patient developed pyogenic mediastinitis 25 days after a heart-lung transplant and required sternal debridement and intravenous penicillin. We also review the literature on thoracopulmonary infections due to A odontolyticus.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Calif., USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Bassiri
authors.forename: R E
authors.initials: RE
authors.lastname: Girgis
authors.forename: J
authors.initials: J
authors.lastname: Theodore
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis* / Q000188:drug therapy; D000284:Administration, Oral; D000328:Adult; D003646:Debridement; D016041:Heart-Lung Transplantation / Q000009:adverse effects; D006801:Humans; D007275:Injections, Intravenous; D016040:Lung Transplantation / Q000009:adverse effects; D008297:Male; D008480:Mediastinitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D010400:Penicillin G / Q000008:administration & dosage / Q000627:therapeutic use; D010404:Penicillin V / Q000008:administration & dosage / Q000627:therapeutic use; D010406:Penicillins / Q000008:administration & dosage / Q000627:therapeutic use; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000188:drug therapy; D013249:Sternum / Q000601:surgery
chemical_list: D010406:Penicillins; D010400:Penicillin G; D010404:Penicillin V