Thromboxane mediates pulmonary vasoconstriction and contributes to cytotoxicity in pig lungs perfused with fresh human blood.
Pierson
R N
RN
Department of Cardiothoracic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37232-5734, USA.
Parker
R E
RE
D001769:Blood; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D008168:Lung / Q000473:pathology*; D008689:Methacrylates / Q000494:pharmacology; D010477:Perfusion; D011651:Pulmonary Artery / Q000502:physiology*; D011652:Pulmonary Circulation / Q000187:drug effects / Q000502:physiology*; D017482:Receptors, Thromboxane / Q000037:antagonists & inhibitors; D013928:Thromboxane A2 / Q000031:analogs & derivatives / Q000494:pharmacology; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors; D013931:Thromboxanes / Q000502:physiology*; D014655:Vascular Resistance / Q000187:drug effects; D014661:Vasoconstriction
D004791:Enzyme Inhibitors; D008689:Methacrylates; D017482:Receptors, Thromboxane; D013931:Thromboxanes; C054215:SQ 30741; D013928:Thromboxane A2; D013930:Thromboxane-A Synthase; C034364:ozagrel