Cancer incidence for children born in a smelting community.
The Rönnskär smelter in Skellefteå, Sweden, produces significant environmental pollutants, such as lead, arsenic, copper, cadmium and sulphur dioxide. The purpose of the present study was to determine whether children born to women living near the smelter during pregnancy had an increased risk of childhood cancer. The study group consisted of children born between 1961 and 1990 in the municipality of Skellefteå and parish of Holmsund. Through linkage to the Swedish Cancer Registry cancer diagnoses in the study group were obtained and compared with the expected ones based on the national incidence rates. Thirteen cases of childhood cancer were identified among children born in the vicinity of the smelter against 6.7 expected (SIR 195, 95%CI 88-300). Among distant born the observed number of cases (n = 42) was similar to that expected (n = 41.8).
Wulff
M
M
Department of Obstetrics and Gynaecology, University of Umeå, Sweden.
Högberg
U
U
Sandström
A
A
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D018811:Maternal Exposure / Q000009:adverse effects*; D008498:Medical Record Linkage; D008669:Metallurgy; D009369:Neoplasms / Q000139:chemically induced* / Q000453:epidemiology*; D016017:Odds Ratio; D011247:Pregnancy; D012042:Registries; D012306:Risk; D013548:Sweden / Q000453:epidemiology