title: Mixed gonadal dysgenesis with gonadoblastoma in a female with Y chromosome: case report.
abstract: A young female with primary amenorrhea and male karyotype (46/XY) is reported. Physical examination and clinical investigation of the patient suggested mixed gonadal dysgenesis (MGD). After gonadectomy, a tumor was found on the left side and histologically diagnosed gonadoblastoma. Postoperative decreased level of testosterone and estradiol reflected the activities of the tumor.
authors.affiliation: Department of Clinical Laboratory Medicine, School of Medicine, University of The Ryukyus, Okinawa, Japan.
authors.forename: A M
authors.initials: AM
authors.lastname: Sadi
authors.forename: T
authors.initials: T
authors.lastname: Toda
authors.forename: M
authors.initials: M
authors.lastname: Kiyuna
authors.forename: H
authors.initials: H
authors.lastname: Miyagi
mesh_terms: D000568:Amenorrhea / Q000235:genetics; D005260:Female; D006060:Gonadal Dysgenesis, Mixed / Q000150:complications* / Q000473:pathology; D018238:Gonadoblastoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008297:Male; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology