[Abnormal neurological findings at first admission in patients with schizophrenia or schizophreniform disorders. Results of computer tomography and measurement of regional cerebral blood flow].
Forty-five patients with schizophrenia or schizophreniform disorder admitted to hospital for the first time had a neurological examination, including integrative sensory and complex motor acts, by a trained neurologist. The patients were studied by CT and regional cerebral blood flow as well. A control group of 24 healthy volunteers was included. The patients had significantly more neurological abnormalities (NA) than the healthy volunteers. Medication did not explain the discrepancy. The NA were associated with sulcal enlargement and smaller brains as visualized by CT but not with ventricular enlargement. There was no association between the regional flow values and NA.
Rubin
P J
PJ
Psykiatrisk afdeling E, Bispebjerg Hospital, København.
Vorstrup
E S
ES
Hemmingsen
R P
RP
Andersen
H S
HS
Bendsen
B B
BB
Strømsø
N J
NJ
Larsen
J K
JK
Bolwig
T G
TG
D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D003718:Denmark; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D010343:Patient Admission; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D012559:Schizophrenia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D014057:Tomography, X-Ray Computed