title: Nipple-areolar preservation during breast-conserving therapy for subareolar breast carcinomas.
abstract: OBJECTIVE
  To determine if women with subareolar breast carcinoma can be successfully treated by breast-conserving therapy consisting of segmental mastectomy that preserves the nipple-areolar complex, axillary lymph node dissection, and postoperative irradiation.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Tertiary care cancer center.
  
  
  METHODS
  Twenty-five patients; median age, 56 years; median tumor diameter, 1.4 cm; and median follow-up, 48 months.
  
  
  METHODS
  Breast-conserving therapy for subareolar primary breast carcinoma.
  
  
  RESULTS
  Two patients had positive surgical margins of resection, and another patient underwent simple mastectomy after developing a local recurrence. Nipple-areolar distortion was the most common cosmetic deformity after breast-conserving therapy, but overall cosmesis was good. At the most recent follow-up, all patients were free of disease.
  
  
  CONCLUSIONS
  Patients who have small subareolar primary breast carcinomas without evidence of nipple involvement are candidates for breast-conserving therapy with nipple-areolar preservation.
authors.affiliation: John Wayne Cancer Institute at Saint John's Hospital and Health Center, Santa Monica, Calif. USA.
authors.forename: P S
authors.initials: PS
authors.lastname: Dale
authors.forename: A E
authors.initials: AE
authors.lastname: Giuliano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D002277:Carcinoma / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D004954:Esthetics; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009558:Nipples; D011446:Prospective Studies