Mouse chromosomal location of three epithelial sodium channel subunit genes and an apical sodium chloride cotransporter gene.
The amiloride-sensitive epithelial sodium channel alpha, beta, and gamma subunit genes, Scnn1a, Scnn1b, and Scnn1g, and the thiazide-sensitive sodium chloride cotransporter gene, Slc12a1, have been mapped in the mouse using an interspecific backcross panel. These loci map to previously defined homologous regions between human and mouse chromosomes and provide additional information regarding human/mouse comparative mapping.
Pathak
B G
BG
Mammalian Genetics Laboratory, ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Frederick, Maryland, 21702, USA.
Shaughnessy
J D
JD
Meneton
P
P
Greeb
J
J
Shull
G E
GE
Jenkins
N A
NA
Copeland
N G
NG
D000818:Animals; D002352:Carrier Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D005796:Genes; D008040:Genetic Linkage; D051379:Mice; D008810:Mice, Inbred C57BL; D009115:Muridae; D015222:Sodium Channels / Q000235:genetics*; D049992:Sodium Chloride Symporters; D027981:Symporters
D002352:Carrier Proteins; D015222:Sodium Channels; D049992:Sodium Chloride Symporters; D027981:Symporters