title: Significance of clonal chromosome aberrations in breast fibroadenomas.
abstract: Despite the high frequency of fibroadenomas of the breast, cytogenetic results are relatively limited. We describe our cytogenetic findings in 30 fibroadenomas. Of these, three showed clonal chromosome abnormalities, i.e., 46,XX,der(6)t(1;6)(q25;p21.3); 48,XX,del(6)(q21),r(11)(?),der(14)t(6;14)(q21;q32),+2mar; and 47,XX,+5.
authors.affiliation: Center for Human Genetics and Genetic Counseling, University of Bremen, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Rohen
authors.forename: B
authors.initials: B
authors.lastname: Staats
authors.forename: U
authors.initials: U
authors.lastname: Bonk
authors.forename: S
authors.initials: S
authors.lastname: Bartnitzke
authors.forename: J
authors.initials: J
authors.lastname: Bullerdiek
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations; D018226:Fibroadenoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged