Errors involving pediatric patients receiving chemotherapy: a literature review.
A review of mishaps involving pediatric patients receiving anticancer chemotherapy was undertaken in order to assist intervention. Although the case literature is too sparse to provide definite recommendations, suggestions for management are made in the event of an error with a high risk (based on the case literature) of life-threatening toxicities. It is recommended that all incidents be reported in the literature in order to provide a basis for devising standard treatment protocols. It is also suggested that studies using animal models continue to be done in order to provide more experimental data about toxicities and potentially beneficial rescue therapies.
Trinkle
R
R
Department of Pharmacy, B.C.'s Children's Hospital, Vancouver, British Columbia, Canada.
Wu
J K
JK
D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000633:toxicity; D002648:Child; D003561:Cytarabine / Q000008:administration & dosage* / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D062787:Drug Overdose; D006801:Humans; D007278:Injections, Spinal; D008508:Medication Errors; D008727:Methotrexate / Q000008:administration & dosage* / Q000633:toxicity; D014748:Vinca Alkaloids / Q000008:administration & dosage* / Q000633:toxicity
D000970:Antineoplastic Agents; D014748:Vinca Alkaloids; D003561:Cytarabine; D008727:Methotrexate