Mechanisms of action of immunosuppressive agents: cyclosporin A, FK506, and rapamycin.
Bierer
B E
BE
Division of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
D000818:Animals; D001665:Binding Sites; D016572:Cyclosporine / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000378:metabolism / Q000494:pharmacology*; D011090:Polyenes / Q000378:metabolism / Q000494:pharmacology*; D015398:Signal Transduction / Q000187:drug effects*; D020123:Sirolimus; D016559:Tacrolimus / Q000378:metabolism / Q000494:pharmacology*
D007166:Immunosuppressive Agents; D011090:Polyenes; D016572:Cyclosporine; D020123:Sirolimus; D016559:Tacrolimus