title: MR diagnosis of retropatellar chondral lesions under compression. A comparison with histological findings.
abstract: OBJECTIVE
  The aim of the study was to improve the chondromalacia patellae (CMP) diagnosis by MR imaging under defined compression of the retropatellar cartilage, using a specially designed knee compressor. The results were compared with histological findings to obtain an MR classification of CMP.
  
  
  METHODS
  MR imaging was performed in in vitro studies of 25 knees from cadavers to investigate the effects of compression on the retropatellar articular cartilage. The results were verified by subsequent histological evaluation.
  
  
  RESULTS
  There was a significant difference in cartilage thickness reduction and signal intensity behaviour under compression according to the stage of CMP.
  
  
  CONCLUSIONS
  Based on the decrease in cartilage thickness, signal intensity behaviour under compression, and cartilage morphology, the studies permitted an MR classification of CMP into stages I-IV in line with the histological findings. Healthy cartilage was clearly distinguished, a finding which may optimize CMP diagnosis.
authors.affiliation: Department of Radiology, Steglitz Medical Centre, Free University of Berlin, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Andresen
authors.forename: S
authors.initials: S
authors.lastname: Radmer
authors.forename: H
authors.initials: H
authors.lastname: König
authors.forename: D
authors.initials: D
authors.lastname: Banzer
authors.forename: K J
authors.initials: KJ
authors.lastname: Wolf
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002102:Cadaver; D002357:Cartilage Diseases / Q000175:diagnosis / Q000473:pathology; D002358:Cartilage, Articular / Q000473:pathology*; D006801:Humans; D066298:In Vitro Techniques; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D010329:Patella / Q000473:pathology*