title: Color Doppler twinkling artifact in hyperechoic regions.
abstract: OBJECTIVE
  To investigate a new color Doppler ultrasound (US) artifact that manifested as a rapidly changing mixture of red and blue behind a strongly reflecting structure.
  
  
  METHODS
  In 140 consecutive patients with parenchymal calcifications seen at US, the presence of color signal was assessed in calcified areas relative to adjacent noncalcified tissue. The artifact, called the twinkling color artifact, was stimulated with various strongly reflecting structures immersed in still water.
  
  
  RESULTS
  The artifact was found in 42 parenchymal calcifications. In vitro experiments showed that the twinkling artifact was present in granular structures, whereas no color signal was noted in smooth surfaces. The "twinkling sign" appeared to be generated by a strongly reflecting medium composed of individual reflectors.
  
  
  CONCLUSIONS
  The presence of a color signal close to calcifications should be interpreted with caution, and a flow spectrum should always be recorded to eliminate the twinkling artifact.
authors.affiliation: Service de Radiologie et d'Imagerie Médicale, Center Hospitalo-Universitaire Henri Mondor 51, Créteil, France.
authors.forename: A
authors.initials: A
authors.lastname: Rahmouni
authors.forename: R
authors.initials: R
authors.lastname: Bargoin
authors.forename: A
authors.initials: A
authors.lastname: Herment
authors.forename: N
authors.initials: N
authors.lastname: Bargoin
authors.forename: N
authors.initials: N
authors.lastname: Vasile
mesh_terms: D016477:Artifacts; D002114:Calcinosis / Q000000981:diagnostic imaging; D002769:Cholelithiasis / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D019047:Phantoms, Imaging; D011446:Prospective Studies; D011467:Prostate / Q000000981:diagnostic imaging; D018615:Ultrasonography, Doppler, Color; D016217:Ultrasonography, Mammary