title: Peripheral joint laxity increases in pregnancy but does not correlate with serum relaxin levels.
abstract: OBJECTIVE
  Our purpose was to evaluate peripheral joint laxity during pregnancy and to determine whether serum relaxin levels are associated with increased joint laxity.
  
  
  METHODS
  A prospective observational study was performed.
  
  
  RESULTS
  A significant increase in joint laxity was found in five of seven peripheral joints over the course of the pregnancy and post partum. There was no correlation with serum relaxin levels. There were no significant differences in joint laxity on the basis of parity, age, or prepregnancy exercise levels.
  
  
  CONCLUSIONS
  Peripheral joint laxity is noted to increase as pregnancy progresses. The cause of this change is undetermined.
authors.affiliation: Department of Obstetrics and Gynecology, Gundersen Medical Foundation, LaCrosse, WI, USA.
authors.forename: C W
authors.initials: CW
authors.lastname: Schauberger
authors.forename: B L
authors.initials: BL
authors.lastname: Rooney
authors.forename: L
authors.initials: L
authors.lastname: Goldsmith
authors.forename: D
authors.initials: D
authors.lastname: Shenton
authors.forename: P D
authors.initials: PD
authors.lastname: Silva
authors.forename: A
authors.initials: A
authors.lastname: Schaper
mesh_terms: D000328:Adult; D000375:Aging / Q000097:blood; D015444:Exercise; D005260:Female; D006801:Humans; D007593:Joint Instability / Q000097:blood*; D010298:Parity; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D011446:Prospective Studies; D012065:Relaxin / Q000097:blood*
chemical_list: D012065:Relaxin