title: Pregnancy in patients with cystic fibrosis.
abstract: With increasing life span of patients with CF, more women with CF are becoming pregnant and others are seeking information about the risks involved during pregnancy and delivery. A striking limitation of the available information is the lack of large prospective studies of pregnant patients with CF matched for age and disease severity compared with their non-pregnant cohorts. A study investigating the effect of pregnancy on morbidity and mortality is being completed by the Cystic Fibrosis Foundation. We recommend that all women with CF be offered contraceptive measures and counseling on the maternal and fetal risks of pregnancy, including the genetic risks for the child. The issue of who will raise the child in the event of subsequent morbidity or maternal mortality should ideally be prospectively discussed.
authors.affiliation: LSUMC, Department of Pediatrics, Shreveport, 71130-3932, USA.
authors.forename: B C
authors.initials: BC
authors.lastname: Hilman
authors.forename: M L
authors.initials: ML
authors.lastname: Aitken
authors.forename: M
authors.initials: M
authors.lastname: Constantinescu
mesh_terms: D003550:Cystic Fibrosis / Q000150:complications / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005298:Fertility; D006801:Humans; D007769:Lactams / Q000493:pharmacokinetics; D009752:Nutritional Status; D010353:Patient Education as Topic; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology / Q000628:therapy; D011256:Pregnancy Outcome; D012042:Registries; D012720:Severity of Illness Index
chemical_list: D007769:Lactams