Case of acute monocytic leukemia with 47,XY,+X,t(2;10)(q21.1;q26.1) and basophilia.
The clinical cytogenetic findings of a patient with acute monocytic leukemia with peripheral and bone marrow basophilia are presented. The cytogenetic analysis of bone marrow cells established a pathologic clone with the following unusual karyotype: 47,XY,+X,t(2;10)(q21.1;q26.1). This chromosome abnormality has not been reported previously in leukemic diseases.
Mitev
L
L
Department of Cytogenetics, Military Medical Academy, Sofia, Bulgaria.
Apostolov
P
P
Manolova
Y
Y
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001491:Basophils / Q000473:pathology*; D002879:Chromosomes, Human, Pair 10; D002889:Chromosomes, Human, Pair 2; D006801:Humans; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012729:Sex Chromosome Aberrations; D014178:Translocation, Genetic; D014960:X Chromosome