title: Hyaluronan-binding properties of human serum hemopexin.
abstract: Hemopexin, the heme-binding serum glycoprotein, exhibits a complex electrophoretic pattern on two-dimensional immunoelectrophoresis on agarose gels into which hyaluronic acid is incorporated in the first and monospecific anti-hemopexin in the second dimension. This heterogeneity reflects a range of interactions of hemopexin isoforms with hyaluronic acid. Electrophoretic patterns of individual human sera greatly differ in their contents of hyaluronan-interacting hemopexin species. Hemopexin itself has no hyaluronidase activity.
authors.affiliation: Department of Cellular Biochemistry, Institute of Hematology and Blood Tranfusion, Prague, Czech Republic.
authors.forename: Z
authors.initials: Z
authors.lastname: Hrkal
authors.forename: K
authors.initials: K
authors.lastname: Kuzelová
authors.forename: U
authors.initials: U
authors.lastname: Muller-Eberhard
authors.forename: R
authors.initials: R
authors.lastname: Stern
mesh_terms: D015180:Electrophoresis, Gel, Two-Dimensional; D004591:Electrophoresis, Polyacrylamide Gel; D006466:Hemopexin / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D006820:Hyaluronic Acid / Q000378:metabolism*; D006821:Hyaluronoglucosaminidase / Q000378:metabolism; D007122:Immunoelectrophoresis
chemical_list: D006820:Hyaluronic Acid; D006466:Hemopexin; D006821:Hyaluronoglucosaminidase