title: Cervical cancer survival in a high risk urban population.
abstract: BACKGROUND
  Cervical cancer remains an important public health problem, particularly for the urban minority population. To the authors' knowledge, determinants of cervical cancer survival have not been studied in this high risk population.
  
  
  METHODS
  This study included all 158 women diagnosed and treated for invasive cervical cancer from January 1, 1986, through December 31, 1992, at the Grady Memorial Hospital and Clinics (Atlanta, GA). Medical records were abstracted to determine age at diagnosis, race, International Federation of Gynecology and Obstetrics (FIGO) clinical stage, treatment, and survival. Pathologic material was reviewed to confirm the diagnosis.
  
  
  RESULTS
  Most patients (80%) were African American, and the stage distribution was similar for African American and white patients. Sixty-six (42%) had FIGO Stage I disease; 50%, Stage II or III; and 8%, Stage IV. Four-year actuarial survival differed significantly according to clinical stage (Ia = 94%, Ib = 79%, II = 39%, III = 26%, IV = 0%). Overall survival was lower for patients with glandular carcinomas than for those with squamous cell carcinomas (26% vs. 55%, P = 0.09). This difference was almost entirely due to increased mortality in patients with Stage Ib adenocarcinomas (53% vs. 88% for squamous cell carcinoma, Stage Ib, P = 0.03).
  
  
  CONCLUSIONS
  The major prognostic markers for cervical cancer survival in this high risk patient population were clinical stage and histology, factors identical to those identified for other populations.
authors.affiliation: Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: W W
authors.initials: WW
authors.lastname: Thoms
authors.forename: E R
authors.initials: ER
authors.lastname: Unger
authors.forename: P R
authors.initials: PR
authors.lastname: Johnson
authors.forename: C O
authors.initials: CO
authors.lastname: Spann
authors.forename: S H
authors.initials: SH
authors.lastname: Hunter
authors.forename: R
authors.initials: R
authors.lastname: Smith
authors.forename: I R
authors.initials: IR
authors.lastname: Horowitz
authors.forename: J P
authors.initials: JP
authors.lastname: Icenogle
authors.forename: S D
authors.initials: SD
authors.lastname: Vernon
authors.forename: W C
authors.initials: WC
authors.lastname: Reeves
mesh_terms: D001741:Black or African American / Q000706:statistics & numerical data; D005260:Female; D005845:Georgia / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D018426:SEER Program; D015996:Survival Rate; D014504:Urban Health; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000208:ethnology / Q000473:pathology; D044465:White People / Q000706:statistics & numerical data