Creatinine and surveys: an assessment.
We analysed the results of surveys on creatinine held in The Netherlands during the years 1992, 1993 and 1994. Assay results of 113 samples were reviewed: 88 human sera and 25 samples of animal origin. The results of 5 creatinine assays, 4 based on the Jaffé reaction and 1 enzymatic procedure, are discussed. The enzymatic assay showed by far the best performance, while some of the Jaffé methods differed considerably. All results were evaluated by reference to a HPLC-based selected method for creatinine. Our study shows the need for caution when applying survey performance criteria for creatinine.
Blijenberg
B G
BG
Department of Clinical Chemistry, University Hospital Rotterdam-Dijkzigt, The Netherlands.
Brouwer
R J
RJ
Baadenhuijsen
H
H
Boerma
G J
GJ
D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003404:Creatinine / Q000097:blood*; D006801:Humans; D009426:Netherlands; D011786:Quality Control; D012016:Reference Values; D012044:Regression Analysis; D015203:Reproducibility of Results
D003404:Creatinine