[Classification and pathogenesis of vasculitides].
Vasculitis is a heterogeneous group of diseases which is characteristic by inflammatory cellular infiltration of the vascular wall often being concomitted by fibrinoid necrosis. The pre-condition for stating the diagnosis is the primary localization of inflammation in the vascular wall. Affliction of vessels can be focal or segmental. Focal vasculitis afflicts merely a part of the vessel's wall perimeter, and aneurysms may develop. Segmental vasculitis refers to a lesion of the entire perimeter of the vascular wall which often leads to stenosis or occlusion of the vessel. Non-specific histologic findings of perivascular infiltrates cannot be considered as evidence of vasculitis. The authors present the classification of vasculitis, its development and relation to etiopathogenesis of the disease, including histopathology and clinical symptoms. (Fig. 1, Tab. 9, Ref. 43.).
Lukác
J
J
Výskumný ústav reumatických chorôb v Piestanoch.
Rovenský
J
J
D006801:Humans; D014657:Vasculitis / Q000145:classification* / Q000209:etiology