title: Sensitivity and specificity analysis for somatic cell count (SCC) used to predict bacteriologically positive subclinical mastitis at calving in a dairy herd with low SCC.
abstract: OBJECTIVE
  Validate, by sensitivity and specificity analyses, use of somatic cell count (SCC) to predict bacteriologically positive subclinical mastitis in a California dairy herd with low SCC.
  
  
  METHODS
  Study of monthly dairy herd improvement SCC obtained from the immediate preceding lactation and individual cow composite milk sample microbiologic isolates collected at calving.
  
  
  METHODS
  515 California dairy cows with SCC and culture data.
  
  
  METHODS
  Somatic cell count sensitivity and specificity analyses with combinations of SCC parameter and at various thresholds were done, using the bacterial isolates as the standard.
  
  
  RESULTS
  Combination of SCC threshold and SCC parameters could not be developed that had sufficient sensitivity and specificity to be a useful predictor of cows that would calve with subclinical mastitis.
  
  
  CONCLUSIONS
  Under the conditions at this particular dairy, SCC could not be used as a basis of prediction of cows that would calve with bacteriologically positive subclinical mastitis or require selective nonlactating-cow antibiotic treatment.
authors.affiliation: Department of Large Animal Surgery and Medicine, College of Veterinary Medicine, Auburn University, AL 36849, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Kirk
authors.forename: S L
authors.initials: SL
authors.lastname: Berry
authors.forename: J P
authors.initials: JP
authors.lastname: Reynolds
authors.forename: J P
authors.initials: JP
authors.lastname: Maas
authors.forename: A
authors.initials: A
authors.lastname: Ahmadi
mesh_terms: D000818:Animals; D002417:Cattle; D002452:Cell Count / Q000662:veterinary; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000517:prevention & control / Q000662:veterinary*; D008414:Mastitis, Bovine / Q000175:diagnosis* / Q000517:prevention & control; D008892:Milk / Q000166:cytology*; D012680:Sensitivity and Specificity