Carcinomatous meningitis complicating cervical cancer: a clinicopathologic study and literature review.
Patients with gynecologic malignancies may develop metastases throughout the neuraxis. Cervix-related carcinomatous meningitis is a distinctly unusual clinical event with only two previous cases reported in the English medical literature. We review clinical, radiographic, and pathologic findings of a woman with advanced adenocarcinoma of the uterine cervix, whose course was complicated by leptomeningeal metastases. Carcinomatous meningitis occurs in the setting of rapidly advancing systemic disease and represents a terminal complication of cervical cancer.
Aboulafia
D M
DM
Division of Hematology/Oncology, Virginia Mason Medical Center, Seattle, Washington 98111, USA.
Taylor
L P
LP
Crane
R D
RD
Yon
J L
JL
Rudolph
R H
RH
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000556:secondary*; D000328:Adult; D003391:Cranial Nerves / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary*; D008581:Meningitis / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000473:pathology*