Congenital nephropathies and uropathies.
Although congenital nephropathies and uropathies only represent a fraction of possible genitourinary diseases detected during childhood, they have serious and sometimes avoidable morbidity and mortality. Advances in genetic, molecular, and cellular biology research continue to better define embryologic insults to normal organogenesis and offer the promise that many of these conditions might be avoided in the future. For now, awareness of these entities and their varied presentations and manifestations is crucial so that prompt evaluation and aggressive multidisciplinary management assures the affected child optimal growth and development.
Becker
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Division of Pediatric Nephrology, University of Washington, Seattle, USA.
Avner
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ED
D006801:Humans; D007674:Kidney Diseases / Q000151:congenital* / Q000175:diagnosis; D014570:Urologic Diseases / Q000151:congenital* / Q000175:diagnosis