Pancytopenia associated with thymoma resolving after thymectomy and immunosuppressive therapy. Case report.
In a 43-year-old woman, pancytopenia accompanying thymoma persisted after thymectomy, requiring weekly blood transfusions, and did not respond to prednisone 50 mg/day. Cyclosporine 10 mg/kg/day plus prednisone 20 mg/day for a month gradually corrected the blood parameters. Thirty months later the patient is well and haematologically stable.
De Giacomo
T
T
Department of Thoracic Surgery, Policlinico Umberto I University of Rome La Sapienza, Italy.
Rendina
E A
EA
Venuta
F
F
Flaishman
I
I
Ricci
C
C
D000328:Adult; D001803:Blood Transfusion; D016572:Cyclosporine / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy*; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D013934:Thymectomy; D013945:Thymoma / Q000150:complications* / Q000601:surgery; D013953:Thymus Neoplasms / Q000150:complications* / Q000601:surgery
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011241:Prednisone