title: Perioperative treatment with phosphatidic acid inhibitor (Lisofylline leads to prolonged survival of hearts in the guinea pig to rat xenotransplant model.
authors.affiliation: Pittsburgh Transplantation Institute, University of Pittsburgh Medical Center, Pennsylvania 15213, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Valdivia
authors.forename: N
authors.initials: N
authors.lastname: Murase
authors.forename: A S
authors.initials: AS
authors.lastname: Rao
authors.forename: G
authors.initials: G
authors.lastname: Rice
authors.forename: J W
authors.initials: JW
authors.lastname: Singer
authors.forename: H
authors.initials: H
authors.lastname: Sun
authors.forename: S
authors.initials: S
authors.lastname: Todo
authors.forename: F
authors.initials: F
authors.lastname: Pan
authors.forename: V
authors.initials: V
authors.lastname: Subbotin
authors.forename: J J
authors.initials: JJ
authors.lastname: Fung
authors.forename: T E
authors.initials: TE
authors.lastname: Starzl
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D000910:Antibodies, Heterophile / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D006085:Graft Survival / Q000187:drug effects* / Q000276:immunology; D006168:Guinea Pigs; D016027:Heart Transplantation / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007432:Intraoperative Period; D008775:Methylprednisolone / Q000627:therapeutic use; D010431:Pentoxifylline / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010712:Phosphatidic Acids / Q000037:antagonists & inhibitors; D051381:Rats; D011917:Rats, Inbred Lew; D014183:Transplantation, Heterologous / Q000276:immunology*
chemical_list: D000276:Adjuvants, Immunologic; D000910:Antibodies, Heterophile; D003176:Complement C3; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D010712:Phosphatidic Acids; C025189:lisofylline; D010431:Pentoxifylline; D008775:Methylprednisolone