A case of vulvar schwannoma.
Schwannoma is generally a solitary, nodular, benign tumor of a peripheral nerve sheath, and it rarely affects the external female genitalia. Its most-common locations are the head, neck, upper and lower extremities, posterior mediastinum, and retroperitoneum. We treated a 29-year-old woman with a vulvar schwannoma. A tumor of 2.5 cm in diameter was resected for treatment and biopsy. It was a capsulate tumor with a smooth surface, and was elastic in consistency. A histological examination revealed a swirling pattern with some palisading of spindle-shaped cells in H.E. stains. Immunohistochemical studies showed the tumor to be positive for S-100 protein and negative for desmin. As a result, the mass proved to be schwannoma originating from the vulva.
Yamashita
Y
Y
Department of Obstetrics and Gynecology, Osaka Medical College, Japan.
Yamada
T
T
Ueki
K
K
Ueki
M
M
Sugimoto
O
O
D000328:Adult; D003893:Desmin / Q000032:analysis; D005260:Female; D006801:Humans; D009442:Neurilemmoma / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis; D014846:Vulvar Neoplasms / Q000473:pathology*
D003893:Desmin; D009418:S100 Proteins