title: [Human T-cell lymphotrophic virus type I and T-cell lymphoma].
abstract: Human T-cell lymphotropic virus type I is an oncogenic retrovirus, endemic in Southwestern Japan, the Caribbean, some parts of Africa and Central and South America. The virus is etiologically associated with adult T-cell leukemia/lymphoma and a myelopathy called tropical spastic paraparesis or HTLV-I associated myelopathy. Transmission of the virus is almost identical to that of HIV. The latency period before onset of clinical symptoms can last from a few years (tropical spastic paraparesis) up to several decades (adult T-cell leukemia/lymphoma). Four different clinicopathological subtypes of the T-cell neoplasia are known, and in this article we describe two patients with the subtype lymphoma.
authors.affiliation: Onkologisk avdeling Det Norske Radiumhospital, Oslo.
authors.forename: A
authors.initials: A
authors.lastname: Loraas
authors.forename: K
authors.initials: K
authors.lastname: Lote
authors.forename: H H
authors.initials: HH
authors.lastname: Samdal
authors.forename: K
authors.initials: K
authors.lastname: Beiske
authors.forename: R
authors.initials: R
authors.lastname: Langholm
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D015481:HTLV-I Antibodies / Q000032:analysis; D015482:HTLV-II Antibodies / Q000032:analysis; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis / Q000473:pathology / Q000635:transmission / Q000821:virology*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D012698:Serologic Tests
chemical_list: D015481:HTLV-I Antibodies; D015482:HTLV-II Antibodies