title: Pulmonary toxicity following exposure to an aerosolized leather protector.
abstract: BACKGROUND
  An aerosol spray for leather protection was reformulated to remove trichloroethane. The new formulation contained isobutane, n-heptane, ethyl acetate and fluoroaliphatics.
  Thirty-nine patients reported symptoms to the regional poison center. Respiratory symptoms developed within hours of exposure. Most symptoms resolved within two days. Abnormal pulmonary function tests, including obstructive disease or diminished diffusing capacity, were demonstrated in three of the four tested patients.
  
  
  CONCLUSIONS
  The mechanism for the pulmonary toxicity has not been determined.
authors.affiliation: Center for Emergency Medical Services, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, USA.
authors.forename: K K
authors.initials: KK
authors.lastname: Burkhart
authors.forename: A
authors.initials: A
authors.lastname: Britt
authors.forename: G
authors.initials: G
authors.lastname: Petrini
authors.forename: S
authors.initials: S
authors.lastname: O'Donnell
authors.forename: J W
authors.initials: JW
authors.lastname: Donovan
mesh_terms: D000085:Acetates / Q000009:adverse effects*; D000293:Adolescent; D000328:Adult; D000336:Aerosols; D002073:Butanes / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D005466:Fluorocarbons / Q000009:adverse effects*; D006536:Heptanes / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000139:chemically induced* / Q000150:complications; D008297:Male; D008875:Middle Aged
chemical_list: D000085:Acetates; D000336:Aerosols; D002073:Butanes; D005466:Fluorocarbons; D006536:Heptanes; C007650:ethyl acetate