Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract.
The in vitro inhibitory effect of Beta vulgaris (beet) root extract on Epstein-Barr virus early antigen (EBV-EA) induction using Raji cells revealed a high order of activity compared to capsanthin, cranberry, red onion skin and short and long red bell peppers. An in vivo anti-tumor promoting activity evaluation against the mice skin and lung bioassays also revealed a significant tumor inhibitory effect. The combined findings suggest that beetroot ingestion can be one of the useful means to prevent cancer.
Kapadia
G J
GJ
Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Howard University, Washington, DC 20059, USA.
Tokuda
H
H
Konoshima
T
T
Nishino
H
H
D000818:Animals; D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D050859:Betacyanins; D005260:Female; D007211:Indoles / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000139:chemically induced / Q000517:prevention & control*; D051379:Mice; D008813:Mice, Inbred ICR; D010860:Pigments, Biological / Q000627:therapeutic use; D010936:Plant Extracts / Q000627:therapeutic use*; D018517:Plant Roots / Q000737:chemistry; D010945:Plants, Edible / Q000737:chemistry*; D012878:Skin Neoplasms / Q000139:chemically induced / Q000517:prevention & control*; D013755:Tetradecanoylphorbol Acetate
D016588:Anticarcinogenic Agents; D050859:Betacyanins; D007211:Indoles; D010860:Pigments, Biological; D010936:Plant Extracts; C020228:betanin; D013755:Tetradecanoylphorbol Acetate