Efficacy of leflunomide to reduce xenoantibody titers in vivo: an evaluation of the prolongation of discordant xenograft survival.
Lucien
J
J
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.
Marath
A
A
Rayat
G
G
Thliveris
J
J
Koshal
A
A
Yatscoff
R
R
D000818:Animals; D000910:Antibodies, Heterophile / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D004797:Enzyme-Linked Immunosorbent Assay; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D016027:Heart Transplantation / Q000276:immunology*; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007166:Immunosuppressive Agents / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D007555:Isoxazoles / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000077339:Leflunomide; D008297:Male; D011817:Rabbits; D013552:Swine; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000276:immunology*
D000910:Antibodies, Heterophile; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D000077339:Leflunomide