title: Craniofacial resection. An alternative incision and skull base repair.
abstract: Neoplasia of the superior group of paranasal sinuses (frontal, ethmoidal and sphenoidal) has an extremely poor prognosis. Resection, preceded or followed by radiotherapy offers a 5 year survival of less than 30% (1). Satisfactory surgical excision has been undermined by difficulties of access to the cribriform plate area, a common site for residual disease. Furthermore the practice of piecemeal removal invariably resulted in inadequate clearance. The craniofacial approach allows not only excellent access to the anterior skull base but also in bloc excision. The results of treating 7 patients with craniofacial resection for tumours in this area are presented. Particular reference is made to a horizontal forehead skin crease incision for intracranial access. A new technique using a combination of surgical, pericranium, partial thickness skin and fibrin glue to repair the skull base defect is described.
authors.affiliation: Ferens Institute of Otolaryngology, Middlesex Hospital, London, Great Britain.
authors.forename: R S
authors.initials: RS
authors.lastname: Dhillon
authors.forename: H R
authors.initials: HR
authors.lastname: Grant
authors.forename: H A
authors.initials: HA
authors.lastname: Crockard
mesh_terms: D000328:Adult; D000368:Aged; D002483:Cellulose, Oxidized / Q000627:therapeutic use; D003399:Craniotomy / Q000379:methods; D062109:Dermatologic Surgical Procedures; D005005:Ethmoid Sinus / Q000601:surgery; D005147:Facial Bones / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D005546:Forehead / Q000601:surgery; D005626:Frontal Sinus / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D018365:Neoplasm, Residual / Q000532:radiotherapy / Q000601:surgery; D010255:Paranasal Sinus Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D016038:Skin Transplantation / Q000379:methods; D012886:Skull / Q000601:surgery*; D013101:Sphenoid Sinus / Q000601:surgery; D015996:Survival Rate; D014014:Tissue Adhesives / Q000627:therapeutic use
chemical_list: D002483:Cellulose, Oxidized; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; C013695:Surgicel