A new translocation, t(5;21)(q13;q22) in acute myelogenous leukemia.
We report a case of acute myelogenous leukemia with a variant translocation involving chromosomes 5 and 21 with breakpoints on 5q13 and 21q22 as revealed by various techniques including fluorescence in situ hybridization. The unusual presentation of t(5;21)(q13;q22), as the sole abnormality in acute myelogenous leukemia, is atypical.
Gogineni
S K
SK
Division of Genetics, Long Island College Hospital, Brooklyn, NY 11201, USA.
da Costa
M
M
Verma
R S
RS
D000208:Acute Disease; D000328:Adult; D002891:Chromosomes, Human, Pair 21 / Q000235:genetics*; D002895:Chromosomes, Human, Pair 5 / Q000235:genetics*; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic / Q000235:genetics*