title: Screening of average-risk individuals for colorectal cancer and postoperative evaluation of patients with colorectal cancer.
abstract: Screening of the average-risk individual for disease creates a different relationship between practitioner and subject than the normal doctor-patient relationship. Screened individuals are asymptomatic, have a whole range of motivations from denial to neurosis, and, for the most part, derive no benefit from the screen, as they are destined never to contract the disease. Rewards to the few must clearly outweigh the risks to the many. The screening strategy must be economical when applied to a large population, safe, and effective in achieving the ultimate goal, which, in the case of colorectal cancer, is reduction in the mortality rate. Prediagnostic screening of asymptomatic adults over the age of 45 years for primary disease has been shown to fulfill all of these criteria. Postoperative screening of asymptomatic individuals after curative resection of colorectal cancer for recurrence has been shown to fulfill none of them.
authors.affiliation: Department of Surgery, University of Illinois College of Medicine at Chicago, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Nelson
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015179:Colorectal Neoplasms / Q000401:mortality / Q000517:prevention & control* / Q000601:surgery; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000191:economics*; D008875:Middle Aged; D011182:Postoperative Care / Q000191:economics; D012307:Risk Factors; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology