title: [Selective vulnerability of neuronal injury after experimental heart arrest].
abstract: The study was aimed at the analysis of vulnerability of the olfactory bulb neurons in dogs after experimental heart arrest lasting for 15 minutes and recirculation lasting for 1 hour. By means of the Nauta degenerative neurohistologic method the reactions of individual types of nerve cells in the olfactory bulb were investigated. Nauta-positive granules were observed in the cytoplasm of the mitral and tufted cells of the olfactory bulb, which are of dopaminergic character. The granulations were present in the cellular areas which are rich in Nissl substance. The granular and short-axon cells of GABA-ergic character which contain a small amount of Nissl granules lack the Nauta-positive granules. Similarly, the Nauta-positive granules were absent in the axon hillock of mitral cells which under normal conditions do not contain the Nissl substance. These results justify the conclusion that ischemia lasting for 15 minutes and one-hour recirculation primarily affect the excitatory neurons rich in the Nissl substance. (Fig. 4, Ref. 16.).
authors.affiliation: Ustav histológie a embryológie Lekárskej fakulty Univerzity P.J. Safárika v Kosiciach.
authors.forename: L
authors.initials: L
authors.lastname: Zachariás
authors.forename: I
authors.initials: I
authors.lastname: Vanický
authors.forename: E
authors.initials: E
authors.lastname: Mechírová
authors.forename: M
authors.initials: M
authors.lastname: Marsala
authors.forename: J
authors.initials: J
authors.lastname: Marsala
mesh_terms: D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004285:Dogs; D006323:Heart Arrest / Q000473:pathology*; D009830:Olfactory Bulb / Q000648:ultrastructure*