title: Three-year open protocol continuation study of oral tolerization with myelin antigens in multiple sclerosis and design of a phase III pivotal trial.
authors.affiliation: Center for Neurologic Diseases, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Hohol
authors.forename: S J
authors.initials: SJ
authors.lastname: Khoury
authors.forename: S L
authors.initials: SL
authors.lastname: Cook
authors.forename: E J
authors.initials: EJ
authors.lastname: Orav
authors.forename: D A
authors.initials: DA
authors.lastname: Hafler
authors.forename: H L
authors.initials: HL
authors.lastname: Weiner
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002417:Cattle; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007108:Immune Tolerance; D007167:Immunotherapy; D008297:Male; D009103:Multiple Sclerosis / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D009186:Myelin Sheath / Q000276:immunology*; D012107:Research Design; D012727:Sex Characteristics; D017211:Treatment Failure