Three-year open protocol continuation study of oral tolerization with myelin antigens in multiple sclerosis and design of a phase III pivotal trial.
Hohol
M J
MJ
Center for Neurologic Diseases, Harvard Medical School, Boston, Massachusetts 02115, USA.
Khoury
S J
SJ
Cook
S L
SL
Orav
E J
EJ
Hafler
D A
DA
Weiner
H L
HL
D000284:Administration, Oral; D000818:Animals; D002417:Cattle; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007108:Immune Tolerance; D007167:Immunotherapy; D008297:Male; D009103:Multiple Sclerosis / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D009186:Myelin Sheath / Q000276:immunology*; D012107:Research Design; D012727:Sex Characteristics; D017211:Treatment Failure