title: Inherited disorders of coagulation in pregnancy.
abstract: Normal physiology has been reviewed to serve as a basis for understanding the abnormalities leading to the inherited coagulation disorders. These abnormalities involve each of the three arms of the coagulation process: platelets, the coagulation cascade, and the clot prevention/lysis pathways. Pregnancy presents a unique challenge to women with these disorders. However, with close attention to the natural course of the disorder and appropriate therapy instituted in a timely fashion, many of these women can achieve successful pregnancies.
authors.affiliation: Louisiana State University Medical Center, New Orleans, USA.
authors.forename: F B
authors.initials: FB
authors.lastname: Rigby
authors.forename: T E
authors.initials: TE
authors.lastname: Nolan
mesh_terms: D001777:Blood Coagulation / Q000502:physiology; D001778:Blood Coagulation Disorders / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D001779:Blood Coagulation Factors / Q000502:physiology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D011256:Pregnancy Outcome
chemical_list: D001779:Blood Coagulation Factors