title: Trisomy 11 with loss of the Y chromosome and trisomy 13 in a case of de novo acute myeloid leukemia.
abstract: We report a man with de novo acute myeloid leukemia (M4 of the FAB classification) bearing two abnormal clones in the bone marrow cells. The clones showed trisomy 11 with loss of the Y chromosome and trisomy 13, respectively.
authors.affiliation: First Department of Internal Medicine, University of Athens School of Medicine, Greece.
authors.forename: J
authors.initials: J
authors.lastname: Meletis
authors.forename: M
authors.initials: M
authors.lastname: Samarkos
authors.forename: D
authors.initials: D
authors.lastname: Abazis
authors.forename: E
authors.initials: E
authors.lastname: Michali
authors.forename: S
authors.initials: S
authors.lastname: Vavourakis
authors.forename: E
authors.initials: E
authors.lastname: Plata
authors.forename: J
authors.initials: J
authors.lastname: Rombos
authors.forename: K
authors.initials: K
authors.lastname: Konstantopoulos
authors.forename: K
authors.initials: K
authors.lastname: Pangalos
authors.forename: X
authors.initials: X
authors.lastname: Yataganas
authors.forename: D
authors.initials: D
authors.lastname: Loukopoulos
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000000981:diagnostic imaging; D002880:Chromosomes, Human, Pair 11; D002882:Chromosomes, Human, Pair 13; D017353:Gene Deletion; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D012074:Remission Induction; D014314:Trisomy; D014463:Ultrasonography; D014998:Y Chromosome