Synthesis and pharmacologic evaluation of 2-endo-amino-3-exo-isopropylbicyclo[2.2.1]heptane: a potent imidazoline1 receptor specific agent.
Munk
S A
SA
Allergan Pharmaceuticals, Irvine, California, 92715, USA.
Lai
R K
RK
Burke
J E
JE
Arasasingham
P N
PN
Kharlamb
A B
AB
Manlapaz
C A
CA
Padillo
E U
EU
Wijono
M K
MK
Hasson
D W
DW
Wheeler
L A
LA
Garst
M E
ME
D000316:Adrenergic alpha-Agonists / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D001794:Blood Pressure / Q000187:drug effects; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D016466:CHO Cells; D006224:Cricetinae; D006536:Heptanes / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D054755:Imidazoline Receptors; D008252:Macaca fascicularis; D051381:Rats; D011955:Receptors, Drug / Q000378:metabolism*
C098523:AGN 192403; D000316:Adrenergic alpha-Agonists; D001643:Bridged Bicyclo Compounds; D006536:Heptanes; D054755:Imidazoline Receptors; D011955:Receptors, Drug