title: Stapled ileal pouch anal anastomoses are safer than handsewn anastomoses in patients with ulcerative colitis.
abstract: BACKGROUND
  One of the theoretic advantages of using a stapled versus handsewn ileal pouch anal anastomosis (IPAA) in restorative proctocolectomy is a reduction in septic complications. We performed this study to compare the incidence of early septic complications in patients undergoing restorative proctocolectomy with stapled or handsewn IPAA.
  
  
  METHODS
  A chart review of 692 patients undergoing restorative proctocolectomy for treatment of ulcerative colitis was performed. The incidence of early septic complications in patients having stapled IPAA was compared to that in patients having handsewn IPAA. Follow-up studies included an annual questionnaire and physical examination.
  
  
  RESULTS
  Of the 692 patients, 238 had handsewn IPAA and 454 had stapled IPAA; these two groups were similar in sex, duration of disease, age at surgery, and type of surgical procedure performed. In the handsewn IPAA group, 25 patients (10.5%) had 32 septic complications, and 24 required 89 reparations. In 7 patients, the pouch was excised. In the stapled IPAA group, 21 patients (4.6%) had 23 septic complications, and 14 required 40 reparations. One patient needed pouch excision. There were more patients (P=0.0001) with early septic complications, and more (P<0.0001) pouch excisions because of these complications, in patients with handsewn IPAA than in patients with stapled IPAA. The sepsis-related reoperation rates did not differ significantly.
  
  
  CONCLUSIONS
  The stapled technique for IPAA has fewer septic complications and results in fewer sepsis-related pouch excisions, in our hands, than the handsewn technique technique, for treating patients with ulcerative colitis.
authors.affiliation: Department of Colorectal Surgery, The Cleveland Clinic Foundation, Ohio, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Ziv
authors.forename: V W
authors.initials: VW
authors.lastname: Fazio
authors.forename: J M
authors.initials: JM
authors.lastname: Church
authors.forename: I C
authors.initials: IC
authors.lastname: Lavery
authors.forename: T M
authors.initials: TM
authors.lastname: King
authors.forename: P
authors.initials: P
authors.lastname: Ambrosetti
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical / Q000379:methods; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D016737:Proctocolectomy, Restorative / Q000379:methods*; D012189:Retrospective Studies; D018805:Sepsis / Q000517:prevention & control; D017792:Surgical Stapling; D013536:Suture Techniques