title: Detection of fibrin in canine neoplasia.
abstract: A murine monoclonal antibody, designated 1H10, produced using a human fibrin-related immunogen, was shown to bind avidly to dog fibrin, but not to dog fibrinogen. Using immunofluorescence, fibrin was detected in canine gastric adenocarcinoma and in mixed tissue from a mammary tumour. No fibrin could be detected in bronchogenic carcinoma tissue.
authors.affiliation: Royal Veterinary College, University of London, North Mymms, Hatfield, UK.
authors.forename: F J
authors.initials: FJ
authors.lastname: McEvoy
authors.forename: T A
authors.initials: TA
authors.lastname: Edgell
authors.forename: P M
authors.initials: PM
authors.lastname: Webbon
authors.forename: P J
authors.initials: PJ
authors.lastname: Gaffney
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000662:veterinary*; D000818:Animals; D000911:Antibodies, Monoclonal; D004285:Dogs; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005337:Fibrin / Q000032:analysis*; D006801:Humans; D013274:Stomach Neoplasms / Q000097:blood / Q000662:veterinary*
chemical_list: D000911:Antibodies, Monoclonal; D005337:Fibrin