FISH studies on the Y chromosome in male urinary cells.
To ascertain the meaning of the loss of the Y (-Y) in bladder cancer, we addressed the incidence of -Y in urinary cells in relation to age in 35 men without bladder cancer. Aside from the bone marrow and blood, -Y has not been examined critically in other tissues and organs in a large series of men. The present study clearly demonstrated that -Y in the group studied was an infrequent finding and not related to age.
Betz
J
J
Southwest Biomedical Research Institute, Scottsdale, Arizona 85251, USA.
Meloni
A M
AM
Sandberg
A A
AA
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002872:Chromosome Deletion; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000652:urine; D014998:Y Chromosome