title: The potential for Laplacian maps to solve the inverse problem of electrocardiography.
abstract: This paper presents a method to solve the inverse problem of electrocardiography using the Laplacian of the body surface potentials. The method presented is studied first using trade-off curves from a concentric spheres model representing a heart-torso system. Then a more conventional study is undertaken where a limited number of current dipoles are placed within the inner sphere and noise is added to the resulting potentials and Laplacians on the surface of the outer sphere. The result indicate that measurements of the outer surface Laplacian can more accurately reconstruct epicardial potentials than measurements of the outer surface potentials. The reconstructions are more accurate in that extrema are placed very close to their correct positions and multiple extrema and high potential gradients are recovered. Identical conclusions are observed in the presence of noise and even when the Laplacians are subject to greater noise than the potentials.
authors.affiliation: Department of Medicine, University of Tasmania, Hobart, Australia. peter@vena.med.utas.edu.au
authors.forename: P R
authors.initials: PR
authors.lastname: Johnston
mesh_terms: D016477:Artifacts; D018780:Body Surface Potential Mapping / Q000379:methods / Q000706:statistics & numerical data; D004562:Electrocardiography / Q000379:methods / Q000706:statistics & numerical data*; D006801:Humans; D008955:Models, Cardiovascular