Human minisatellite mutation rate after the Chernobyl accident.
Germline mutation at human minisatellite loci has been studied among children born in heavily polluted areas of the Mogilev district of Belarus after the Chernobyl accident and in a control population. The frequency of mutation was found to be twice as high in the exposed families as in the control group. Mutation rate in the Mogilev families was correlated with the level of caesium-137 surface contamination, consistent with radiation induction of germline mutation.
Dubrova
Y E
YE
N. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Nesterov
V N
VN
Krouchinsky
N G
NG
Ostapenko
V A
VA
Neumann
R
R
Neil
D L
DL
Jeffreys
A J
AJ
D000328:Adult; D002588:Cesium Radioisotopes; D015331:Cohort Studies; D016172:DNA Fingerprinting; D015342:DNA Probes; D004276:DNA, Satellite / Q000235:genetics / Q000528:radiation effects*; D005260:Female; D018095:Germ-Line Mutation; D006801:Humans; D007223:Infant; D008297:Male; D009154:Mutation; D011210:Power Plants; D011847:Radioactive Fallout; D018788:Radioactive Hazard Release; D014455:Ukraine
D002588:Cesium Radioisotopes; D015342:DNA Probes; D004276:DNA, Satellite; D011847:Radioactive Fallout