title: Malignant degeneration in leiomyomatosis peritonealis disseminata.
abstract: Leiomyomatosis peritonealis disseminata (LPD) is a rare clinico-pathologic entity typically observed in women of reproductive age. Its malignant degeneration has been reported in literature in only three cases. In this report we describe the clinical course of two more cases with proved malignant transformation of LPD; both cases were treated with combined chemotherapy.
authors.affiliation: Department of Surgical Gynecologic Oncology, Instituto Nazionale Tumori, Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Raspagliesi
authors.forename: P
authors.initials: P
authors.lastname: Quattrone
authors.forename: G
authors.initials: G
authors.lastname: Grosso
authors.forename: L
authors.initials: L
authors.lastname: Cobellis
authors.forename: E
authors.initials: E
authors.lastname: Di Re
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002471:Cell Transformation, Neoplastic; D003606:Dacarbazine / Q000627:therapeutic use; D015251:Epirubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000627:therapeutic use; D018231:Leiomyomatosis / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D015251:Epirubicin; D003606:Dacarbazine; D007069:Ifosfamide