title: Photothermal sclerosis of leg veins. ESC Medical Systems, LTD Photoderm VL Cooperative Study Group.
abstract: BACKGROUND
  The flashlamp-pumped pulse dye laser at 585 nm has previously been reported to be somewhat effective in treating leg telangiectasia with diameters less than 0.2 mm. A pulsed photothermal devise (intense pulsed light source [IPLS]) has been developed to treat leg veins ranging in size from 0.1 to 3 mm in diameter. Vessel necrosis occurs from an intense pulsed light that penetrates through the skin and is absorbed by the blood vessels based on the principle of selective photothermolysis.
  
  
  OBJECTIVE
  To determine the effectiveness of this novel device on treating leg veins.
  
  
  METHODS
  One hundred fifty-nine patients with 369 lesions were treated with the IPLS in a multicenter trial.
  
  
  RESULTS
  Clearance of 75-100% was achieved in 79% of treated lesions. Better than 50% clearance was achieved in 94% of completed cases. A very low rate of adverse effects occurred.
  
  
  CONCLUSIONS
  The IPLS is a safe and effective modality to treat leg veins ranging in size from 0.1 to 3 mm in diameter.
authors.affiliation: Dermatology Associates of San Diego County, Inc., California, La Jolla 92037, USA.
authors.forename: M P
authors.initials: MP
authors.lastname: Goldman
authors.forename: S
authors.initials: S
authors.lastname: Eckhouse
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008028:Light Coagulation / Q000009:adverse effects / Q000379:methods; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000209:etiology; D011446:Prospective Studies; D011693:Purpura / Q000209:etiology; D013684:Telangiectasis / Q000601:surgery; D014648:Varicose Veins / Q000601:surgery*