title: Oral submucous fibrosis: a new concept in surgical management. Report of 100 cases.
abstract: Oral submucous fibrosis (OSF) is a collagen disorder commonly seen in the Indian subcontinent. A series of 100 patients is presented. All lesions were biopsied. The condition was staged into four categories. Very early and early cases were treated by local injection of triamicinolone acetonide, while advanced cases were treated by surgical intervention. A new surgical technique of a palatal island flap based on the greater palatine artery in combination with temporalis myotomoy and bilateral coronoidectomy was used in 35 cases. A follow-up ranging from 6 months to 31/2 year showed good results.
authors.affiliation: Department of Oral and Maxillofacial and Plastic Surgery, Nair Hospital Dental College, Bombay, India.
authors.forename: J N
authors.initials: JN
authors.lastname: Khanna
authors.forename: N N
authors.initials: NN
authors.lastname: Andrade
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001158:Arteries; D001706:Biopsy; D002648:Child; D003095:Collagen Diseases / Q000145:classification / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007194:India; D015552:Injections, Intralesional; D008297:Male; D008334:Mandible / Q000601:surgery; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000145:classification / Q000473:pathology / Q000601:surgery; D009914:Oral Submucous Fibrosis / Q000145:classification / Q000473:pathology / Q000601:surgery*; D010159:Palate / Q000098:blood supply / Q000601:surgery; D011230:Precancerous Conditions / Q000145:classification / Q000473:pathology / Q000601:surgery; D013524:Surgical Flaps / Q000379:methods; D013703:Temporal Muscle / Q000637:transplantation; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide