Iobitridol 250 vs iohexol 240 in phlebography of th lower limbs. A double-blind clinical trial.
Iobitridol 250 (Xenetix 250) was compared with iohexol 240 (Omnipaque 240) in phlebography of the lower limbs by means of a multicenter, randomized double-blind trial in 70 patients. No significant difference was demonstrated between the 2 groups in terms of diagnostic efficacy, image quality or clinical safety. Only minor reactions were recorded in the 2 groups, essentially consisting of mild or moderate heat sensations. The only insufficiently informative examinations were not due to the contrast agent. Iobitridol 250 therefore appears to be a well-tolerated contrast medium, suitable for use in phlebography of the lower limbs.
Chagnaud
C
C
Radiology Department at Timone Hospital, Marseille, France.
Moulin
G
G
Bartoli
J M
JM
Rousseau
H
H
Railhac
J J
JJ
Lyonnet
D
D
D003287:Contrast Media / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007472:Iohexol / Q000009:adverse effects / Q000031:analogs & derivatives*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D010690:Phlebography
D003287:Contrast Media; C093233:iobitridol; D007472:Iohexol