A plasma cell variant of Castleman's disease treated successfully with cimetidine. Case report and review of the literature.
Castleman's disease is a rare benign condition of uncertain etiology, with several forms. It is postulated that a dysregulated inflammatory response may play a role in the pathogenesis of this disease. We report on a case of Castleman's disease treated with the histamine receptor-2 antagonist cimetidine with favourable response, suggesting that cimetidine may be helpful in the treatment of this disease.
Barbounis
V
V
2nd Department of Medical Oncology, St. Savvas Regional Anticancer Hospital, Athens, Greece.
Efremidis
A
A
D000328:Adult; D005871:Castleman Disease / Q000188:drug therapy* / Q000473:pathology*; D002927:Cimetidine / Q000627:therapeutic use*; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010950:Plasma Cells / Q000473:pathology*
D006635:Histamine H2 Antagonists; D002927:Cimetidine