title: A combined endoscopic Co2 laser and external approach for treatment of glottic cancer involving the anterior commissure: an animal study.
abstract: Endoscopic laser resection usually has been discouraged for anterior commissure (AC) carcinoma because of inadequate exposure and close proximity to underlying cartilage. A new technique combining endoscopic CO2 laser incision and an external approach, creating a window in the thyroid cartilage, was tested in this in vivo study of six dogs. An en bloc specimen including adjacent cartilage was excised while preserving the thyroid framework. The glottic reconstruction was accomplished with external placement of a sternohyoid muscle flap, by either using a bipedicled muscle flap with overlying skin or a unipedicled muscle flap with a graft of free mucosa. The results showed a satisfactory anatomic reconstruction and acceptable functions. The bipedicled muscle flap was superior to the unipedicled muscle flap due to a better AC reconstruction. It is believed that this new combined technique may overcome limited access with endoscopic technique and excessive cartilage resection with the external partial laryngectomy.
authors.affiliation: Department of Otlaryngology-Head and Neck Surgery, New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA.
authors.forename: S M
authors.initials: SM
authors.lastname: Shapshay
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: E E
authors.initials: EE
authors.lastname: Rebeiz
authors.forename: D F
authors.initials: DF
authors.lastname: Perrault
authors.forename: M M
authors.initials: MM
authors.lastname: Pankratov
mesh_terms: D000818:Animals; D002245:Carbon Dioxide; D004285:Dogs; D005931:Glottis / Q000473:pathology / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007828:Laryngoscopy; D053685:Laser Therapy / Q000379:methods*
chemical_list: D002245:Carbon Dioxide