Necrotizing myopathy with pipestem capillaries and minimal cellular infiltration: a case associated with cutaneous signs of dermatomyositis.
In 1991, Emslie-Smith and Engel described a distinct form of idiopathic inflammatory myopathy they called "necrotizing myopathy with pipestem capillaries, microvascular deposition of the complement membrane attack complex (MAC) and minimal cellular infiltration." We describe a patient with exercise-dependent painful myopathy related to a necrotizing myopathy with pipestem capillaries in whom mild cutaneous signs of dermatomyositis were detected 7 years after onset and who subsequently developed multiple cerebral infarcts.
Authier
F J
FJ
Groupe Nerf-Muscle, Hôpital Henri-Mondor, Faculté de Médecine, Créteil, Paris.
Kondo
H
H
Ghnassia
R T
RT
Revuz
J
J
Gherardi
R K
RK
D002196:Capillaries / Q000473:pathology* / Q000648:ultrastructure; D002544:Cerebral Infarction; D003882:Dermatomyositis / Q000473:pathology* / Q000503:physiopathology; D004576:Electromyography; D004730:Endothelium, Vascular / Q000473:pathology / Q000648:ultrastructure; D005500:Follow-Up Studies; D006801:Humans; D007249:Inflammation; D008264:Macrophages / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D018485:Muscle Fibers, Skeletal / Q000473:pathology / Q000648:ultrastructure; D018482:Muscle, Skeletal / Q000473:pathology* / Q000648:ultrastructure; D009336:Necrosis; D010146:Pain; D014652:Vascular Diseases / Q000473:pathology*