title: Sterilization of chitosan: implications.
abstract: Chitosan, a biopolysaccharide having structural characteristics similar to glycosaminoglycans, seems to be an ideal non-toxic and bioabsorbable biopolymer. This study highlights the effects of some physical and chemical methods of sterilization on chitosan films, in retaining the original tensile strength besides the efficacy of sterility and degree of hemolysis of the finished films.
authors.affiliation: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Poojappura, Trivandrum, India.
authors.forename: S B
authors.initials: SB
authors.lastname: Rao
authors.forename: C P
authors.initials: CP
authors.lastname: Sharma
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology / Q000528:radiation effects; D001704:Biopolymers / Q000737:chemistry / Q000494:pharmacology / Q000528:radiation effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002686:Chitin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology / Q000528:radiation effects; D048271:Chitosan; D004202:Disinfectants; D005027:Ethylene Oxide; D005720:Gamma Rays; D005976:Glutaral; D006461:Hemolysis / Q000187:drug effects; D013227:Steam; D013242:Sterilization / Q000379:methods*; D013696:Temperature; D013718:Tensile Strength; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D001704:Biopolymers; D004202:Disinfectants; D013227:Steam; D002686:Chitin; D048271:Chitosan; D005027:Ethylene Oxide; D005976:Glutaral