Molecular basis of immunosuppressive drug action: regulation of steroid receptor-mediated transcription by FK 506.
Butt
T R
TR
SmithKline Beecham Pharmaceuticals, Research and Development, King of Prussia, Pennsylvania, USA. butt@al.mscf.upenn.edu.
Graumann
K
K
Aziz
S
S
D002352:Carrier Proteins / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D017353:Gene Deletion; D006360:Heat-Shock Proteins / Q000235:genetics; D006727:Hormone Antagonists / Q000494:pharmacology; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D015735:Mifepristone / Q000494:pharmacology; D011374:Progesterone / Q000494:pharmacology*; D011980:Receptors, Progesterone / Q000096:biosynthesis / Q000187:drug effects / Q000378:metabolism*; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000187:drug effects / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D016559:Tacrolimus / Q000494:pharmacology*; D022021:Tacrolimus Binding Proteins; D014158:Transcription, Genetic / Q000187:drug effects*; D001616:beta-Galactosidase / Q000096:biosynthesis*
D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D006360:Heat-Shock Proteins; D006727:Hormone Antagonists; D007166:Immunosuppressive Agents; D011980:Receptors, Progesterone; D011994:Recombinant Proteins; D015735:Mifepristone; D011374:Progesterone; D001616:beta-Galactosidase; D022021:Tacrolimus Binding Proteins; D016559:Tacrolimus