Proteins that bind to and mediate the biological activity of platinum anticancer drug-DNA adducts.
Whitehead
J P
JP
Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139, USA.
Lippard
S J
SJ
D000595:Amino Acid Sequence; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D001426:Bacterial Proteins / Q000378:metabolism; D001483:Base Sequence; D002945:Cisplatin / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D018736:DNA Adducts; D004260:DNA Repair; D006609:High Mobility Group Proteins / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008322:Mammals; D008961:Models, Structural; D008969:Molecular Sequence Data; D010984:Platinum; D017433:Protein Structure, Secondary; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D013237:Stereoisomerism
D000970:Antineoplastic Agents; D001426:Bacterial Proteins; D018736:DNA Adducts; D006609:High Mobility Group Proteins; C034697:transplatin; D010984:Platinum; D004247:DNA; D002945:Cisplatin