Ion channels: too complex for rational drug design?
Goldstein
S A
SA
Department of Pediatrics, Yale University School of Medicine, New Haven, Conneticut 06536-0812, USA.
Colatsky
T J
TJ
D018528:ATP-Binding Cassette Transporters; D000818:Animals; D002118:Calcium / Q000502:physiology; D015220:Calcium Channels / Q000187:drug effects; D015195:Drug Design; D006321:Heart / Q000502:physiology; D006339:Heart Rate; D006801:Humans; D015640:Ion Channel Gating / Q000187:drug effects; D007473:Ion Channels / Q000187:drug effects* / Q000502:physiology; D008564:Membrane Potentials; D010179:Pancreas / Q000502:physiology; D015221:Potassium Channels / Q000187:drug effects; D024661:Potassium Channels, Inwardly Rectifying; D011955:Receptors, Drug / Q000187:drug effects; D015222:Sodium Channels / Q000187:drug effects; D064233:Sulfonylurea Receptors
D018528:ATP-Binding Cassette Transporters; D015220:Calcium Channels; D007473:Ion Channels; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D011955:Receptors, Drug; D015222:Sodium Channels; D064233:Sulfonylurea Receptors; D002118:Calcium