Managing HIV. Part 3. Mechanisms of disease. 3.2 How HIV produces immune deficiency.
Initially, the immune system controls HIV infection, but over time the virus depletes the population of CD4+ T cells and disturbs the homoeostasis and function of other cells in the immune system. Extensive destruction of the immune system eventually leaves the body defenceless.
Ffrench
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Department of Clinical Immunology and Allergy, Westmead Hospital, Sydney, NSW, Australia.
Stewart
G J
GJ
Penny
R
R
Levy
J A
JA
D015704:CD4 Antigens; D006678:HIV / Q000472:pathogenicity* / Q000502:physiology; D015658:HIV Infections / Q000276:immunology* / Q000401:mortality / Q000503:physiopathology; D006801:Humans; D007109:Immunity / Q000502:physiology; D008198:Lymph Nodes / Q000821:virology; D017741:Survivors; D014774:Virulence; D014779:Virus Replication
D015704:CD4 Antigens