Callus formation in femur and tibia during leg lengthening: 7 patients examined with DXA.
We examined the callus formation during leg lengthening in 7 achondroplastic patients who underwent 3 bilateral femoral and 4 bilateral tibial lengthenings. Bone mineral content and bone mineral density (BMD) in the lengthened callus space were evaluated every 1 or 2 weeks for 10 weeks after the start of distraction using dual energy X-ray absorptiometry. The mean rate of callus mineralization in femurs (0.64 g/wk) was higher than in tibias (0.22 g/wk). The mean BMD at 10 weeks after the start was 0.35 g/cm2 in the femur and 0.14 g/cm2 in the tibia. Different rates of callus formation in different kinds of long tubular bones have not been reported previously.
Tanaka
K
K
Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Japan.
Kurokawa
T
T
Nakamura
K
K
Matsushita
T
T
Horinaka
S
S
Kusaba
I
I
Okazaki
H
H
Mamada
K
K
Shiro
R
R
Ou
W
W
Hung
S C
SC
D000130:Achondroplasia / Q000503:physiopathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D001852:Bone Lengthening; D002146:Bony Callus / Q000503:physiopathology*; D002648:Child; D005260:Female; D005269:Femur / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D013977:Tibia / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors