title: Isolation of a cDNA clone, TRX encoding a human T-cell lymphotrophic virus type-I Tax1 binding protein.
abstract: Tax1 is essential for human T-cell lymphotropic virus type I (HTLV-I) virus replication and transformation. We have identified and characterized a Tax1 binding protein, TRX, by cDNA screening of a Jurkat T-cell cDNA library. TRX mRNA is ubiquitously expressed in human tissues tested and cell lines analyzed.
authors.affiliation: Laboratory of Molecular Virology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: A
authors.initials: A
authors.lastname: Mireskandari
authors.forename: R L
authors.initials: RL
authors.lastname: Reid
authors.forename: F
authors.initials: F
authors.lastname: Kashanchi
authors.forename: J
authors.initials: J
authors.lastname: Dittmer
authors.forename: W B
authors.initials: WB
authors.lastname: Li
authors.forename: J N
authors.initials: JN
authors.lastname: Brady
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002352:Carrier Proteins / Q000235:genetics* / Q000378:metabolism; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics*; D016356:Gene Products, tax / Q000378:metabolism*; D005796:Genes; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000235:genetics / Q000473:pathology; D008214:Lymphocytes / Q000378:metabolism; D008565:Membrane Proteins; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D014407:Tumor Cells, Cultured
chemical_list: D002352:Carrier Proteins; D018076:DNA, Complementary; D016356:Gene Products, tax; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; D012333:RNA, Messenger; C494631:VAC14 protein, human