title: Blepharospasm in association with a lower pontine lesion.
abstract: A patient with neurofibromatosis type I and breast carcinoma developed a bilateral but asymmetric blepharospasm and paresis of the left abducens muscle over a 2-week course. MRI disclosed a small lesion in the left dorsomedial lower pontine region. Electrodiagnostic investigations revealed bilateral R1 responses after stimulation of the left supraorbital nerve and enhancement of R1 and R2 recovery curves. We concluded that lesions in the lower pontine tegmentum may cause blepharospasm.
authors.affiliation: Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Aramideh
authors.forename: B W
authors.initials: BW
authors.lastname: Ongerboer de Visser
authors.forename: G
authors.initials: G
authors.lastname: Holstege
authors.forename: C B
authors.initials: CB
authors.lastname: Majoie
authors.forename: J D
authors.initials: JD
authors.lastname: Speelman
mesh_terms: D001764:Blepharospasm / Q000473:pathology* / Q000503:physiopathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000503:physiopathology; D002552:Cerebral Ventricles / Q000473:pathology; D004576:Electromyography; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000473:pathology / Q000503:physiopathology; D009801:Oculomotor Muscles / Q000503:physiopathology*; D011149:Pons / Q000473:pathology* / Q000503:physiopathology*; D011859:Radiography