title: MHC expression of African green monkeys of Barbados is limited in heterogeneity.
abstract: Major histocompatibility complex expression of activated peripheral blood lymphocytes of captive African green monkeys from Barbados and from Africa were analyzed biochemically; class I molecules by one-dimensional isoelectric focusing and class II DR molecules by one-dimensional nonequilibrium pH gradient electrophoresis. Much less diversity was observed in the major histocompatability molecule expression of the African green monkeys of Barbados than in the African cohort.
authors.affiliation: Harvard Medical School, New England Regional Primate Research Center, Southborough, MA, USA.
authors.forename: C
authors.initials: C
authors.lastname: Lekutis
authors.forename: N L
authors.initials: NL
authors.lastname: Letvin
mesh_terms: D000349:Africa; D000818:Animals; D001460:Barbados; D002522:Chlorocebus aethiops / Q000276:immunology*; D015870:Gene Expression; D014644:Genetic Variation; D005843:Geography; D006684:HLA-DR Antigens / Q000032:analysis / Q000096:biosynthesis / Q000302:isolation & purification; D015395:Histocompatibility Antigens Class I / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification; D000949:Histocompatibility Antigens Class II / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification; D007525:Isoelectric Focusing; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008285:Major Histocompatibility Complex
chemical_list: D006684:HLA-DR Antigens; D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II