title: Callus formation in femur and tibia during leg lengthening: 7 patients examined with DXA.
abstract: We examined the callus formation during leg lengthening in 7 achondroplastic patients who underwent 3 bilateral femoral and 4 bilateral tibial lengthenings. Bone mineral content and bone mineral density (BMD) in the lengthened callus space were evaluated every 1 or 2 weeks for 10 weeks after the start of distraction using dual energy X-ray absorptiometry. The mean rate of callus mineralization in femurs (0.64 g/wk) was higher than in tibias (0.22 g/wk). The mean BMD at 10 weeks after the start was 0.35 g/cm2 in the femur and 0.14 g/cm2 in the tibia. Different rates of callus formation in different kinds of long tubular bones have not been reported previously.
authors.affiliation: Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Kurokawa
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Matsushita
authors.forename: S
authors.initials: S
authors.lastname: Horinaka
authors.forename: I
authors.initials: I
authors.lastname: Kusaba
authors.forename: H
authors.initials: H
authors.lastname: Okazaki
authors.forename: K
authors.initials: K
authors.lastname: Mamada
authors.forename: R
authors.initials: R
authors.lastname: Shiro
authors.forename: W
authors.initials: W
authors.lastname: Ou
authors.forename: S C
authors.initials: SC
authors.lastname: Hung
mesh_terms: D000130:Achondroplasia / Q000503:physiopathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D001852:Bone Lengthening; D002146:Bony Callus / Q000503:physiopathology*; D002648:Child; D005260:Female; D005269:Femur / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D013977:Tibia / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors