Anaphylactic reaction to cefazolin in pregnancy.
Anaphylaxis is a rare event in pregnancy, but is one that can have serious implications for both the mother and fetus. We report a case of severe anaphylactic reaction to intravenous (i.v.) cefazolin (CEZ) given during labor with premature rupture of membranes. Maternal shock and prolonged fetal bradycardia occurred. Both the maternal and fetal outcomes were good following treatment with ephedrine, glucocorticoids, and emergency caesarean section.
Konno
R
R
Department of Obstetrics and Gynecology, Iwate Prefectural Iwai Hospital, Ichinoseki, Japan.
Nagase
S
S
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced* / Q000150:complications; D002437:Cefazolin / Q000009:adverse effects* / Q000627:therapeutic use; D002511:Cephalosporins / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000188:drug therapy*; D006801:Humans; D011247:Pregnancy
D002511:Cephalosporins; D002437:Cefazolin