A novel serpin-like protein, B-43, exists in both neurons and astrocytes: an immunohistochemical study in the parietal region of the bovine brain.
The presence of a novel member of serine proteinase inhibitor, B-43, was immunohistochemically indicated in both neurons and astrocytes in the parietal region of the bovine brain. B-43-like immunoreactivity was detected in pyramidal cells in the cortex and GFAP-positive astroglial cells in the white matter. The processes of B-43 may play a cooperative role with glia-derived nexin/protease nexin-1 and alpha 1-antichymotrypsin in the brain.
Nishibori
M
M
Department of Pharmacology, Okayama University Medical School, Japan.
Ohtsuka
A
A
Kawabata
M
M
Nakaya
N
N
Murakami
T
T
Saeki
K
K
D000818:Animals; D000918:Antibody Specificity; D001253:Astrocytes / Q000737:chemistry*; D015153:Blotting, Western; D002417:Cattle; D003712:Dendrites / Q000737:chemistry; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D007150:Immunohistochemistry; D009474:Neurons / Q000737:chemistry* / Q000648:ultrastructure; D010296:Parietal Lobe / Q000166:cytology*; D011817:Rabbits; D015842:Serine Proteinase Inhibitors / Q000032:analysis* / Q000276:immunology; D015843:Serpins / Q000032:analysis* / Q000276:immunology
D005904:Glial Fibrillary Acidic Protein; D015842:Serine Proteinase Inhibitors; D015843:Serpins