title: Bronchogenic carcinoma and coexistent bronchioloalveolar cell adenomas. Assessment of radiologic detection and follow-up in 28 patients.
abstract: OBJECTIVE
  Bronchioloalveolar cell adenomas (BAAs) have been described in up to 10% of patients with bronchogenic carcinoma. Their prognostic significance is unknown. The purpose of this study was to determine the prognostic implications of finding BAAs coexisting in specimens resected for primary bronchogenic carcinoma and to determine how frequently BAAs can be detected radiologically.
  
  
  METHODS
  Follow-up information for a mean of 30 months was obtained on 28 patients with a single primary bronchogenic carcinoma and one or more coexistent BAAs. Preoperative chest radiographs (n=27) and CT scans (n=24) were retrospectively reviewed to assess the number of patients in whom BAAs could be detected radiologically.
  
  
  RESULTS
  There was no significant difference between percentage survival of patients with a primary bronchogenic carcinoma and coexistent BAAs when compared with the percentage predicted survival of these patients based on their primary bronchogenic carcinoma alone. BAAs could be detected retrospectively in 1 of 27 (4%) preoperative radiographs and 11 of 24 (46%) CT scans.
  
  
  CONCLUSIONS
  On standard preoperative imaging for bronchogenic carcinoma, BAAs were retrospectively detected in more than one third of patients in whom they were detected pathologically. However, the presence of coexistent BAAs with bronchogenic carcinoma does not affect short- and medium-term prognosis.
authors.affiliation: Department of Radiology, University of British Columbia, Vancouver, Canada.
authors.forename: P M
authors.initials: PM
authors.lastname: Logan
authors.forename: R R
authors.initials: RR
authors.lastname: Miller
authors.forename: K
authors.initials: K
authors.lastname: Evans
authors.forename: N L
authors.initials: NL
authors.lastname: Muller
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology; D002283:Carcinoma, Bronchogenic / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology; D011379:Prognosis; D011859:Radiography; D012189:Retrospective Studies; D015996:Survival Rate