title: Percutaneous endoscopic gastrostomy in children: influence on gastroesophageal reflux.
abstract: OBJECTIVE
  Few data exist in the literature about the relationship between percutaneous endoscopic gastrostomy (PEG) and gastroesophageal reflux (GER) in children, and the data that do exist are contradictory. The aim of the present study was to evaluate the effect of PEG on GER.
  
  
  METHODS
  Twenty children underwent PEG for enteral nutrition. They were 55 +/- 55 months old and weighed 13 +/- 10 kg. A pH study was performed before and after PEG without treatment when GER status was unknown (n = 10) or under treatment (n = 10) if previous GER was demonstrated. In these cases, the pH study was performed under the same treatment before and after PEG.
  
  
  RESULTS
  Six pH studies had abnormal results before PEG. After PEG, the GER of these 6 children significantly improved after the treatment was intensified (n = 50 or spontaneously normalized (n = 1). Results of 13 pH studies that were previously normal remained normal. Only one child with a normal reflux index before PEG had GER after it. For the 20 children, the mean reflux index did not change significantly after PEG (5.5% vs 5.6%).
  
  
  CONCLUSIONS
  Contrary to surgical gastrostomy, PEG does not worsen GER. Therefore, GER is not a contraindication to PEG.
authors.affiliation: Department of Pediatric Gastroenterology, University Hospital, Lille, France.
authors.forename: V
authors.initials: V
authors.lastname: Launay
authors.forename: F
authors.initials: F
authors.lastname: Gottrand
authors.forename: D
authors.initials: D
authors.lastname: Turck
authors.forename: L
authors.initials: L
authors.lastname: Michaud
authors.forename: S
authors.initials: S
authors.lastname: Ategbo
authors.forename: J P
authors.initials: JP
authors.lastname: Farriaux
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D000075202:Contraindications; D004750:Enteral Nutrition; D005260:Female; D005336:Fiber Optic Technology / Q000295:instrumentation; D005744:Gastric Acid / Q000502:physiology; D005746:Gastric Emptying / Q000187:drug effects; D005764:Gastroesophageal Reflux / Q000188:drug therapy / Q000503:physiopathology*; D005773:Gastroscopy; D005774:Gastrostomy / Q000295:instrumentation / Q000379:methods; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008297:Male; D054328:Proton Pump Inhibitors
chemical_list: D054328:Proton Pump Inhibitors