Trisomy 11 with loss of the Y chromosome and trisomy 13 in a case of de novo acute myeloid leukemia.
We report a man with de novo acute myeloid leukemia (M4 of the FAB classification) bearing two abnormal clones in the bone marrow cells. The clones showed trisomy 11 with loss of the Y chromosome and trisomy 13, respectively.
Meletis
J
J
First Department of Internal Medicine, University of Athens School of Medicine, Greece.
Samarkos
M
M
Abazis
D
D
Michali
E
E
Vavourakis
S
S
Plata
E
E
Rombos
J
J
Konstantopoulos
K
K
Pangalos
K
K
Yataganas
X
X
Loukopoulos
D
D
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000000981:diagnostic imaging; D002880:Chromosomes, Human, Pair 11; D002882:Chromosomes, Human, Pair 13; D017353:Gene Deletion; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D012074:Remission Induction; D014314:Trisomy; D014463:Ultrasonography; D014998:Y Chromosome