title: Biochemical modulation of fluoropyrimidines: is there an optimal (6R,S) leucovorin dose and schedule?
authors.forename: J H
authors.initials: JH
authors.lastname: Doroshow
mesh_terms: D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use* / Q000633:toxicity; D003110:Colonic Neoplasms / Q000188:drug therapy*; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D005467:Floxuridine / Q000009:adverse effects / Q000627:therapeutic use* / Q000633:toxicity; D005472:Fluorouracil / Q000009:adverse effects / Q000627:therapeutic use* / Q000633:toxicity; D006801:Humans; D002955:Leucovorin / Q000494:pharmacology* / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005467:Floxuridine; D002955:Leucovorin; D005472:Fluorouracil