title: [Stage I and II endometrial cancer: should lymphadenectomy still be done?].
abstract: Surgical treatment for endometrial carcinomas stage I and II is radical hysterectomy. The role of lymphadenectomy (pelvic and paraaortic) is under discussion. From a retrospective study (multivariate analysis of 320 patients treated by radiosurgical association) and a review of the literature, the authors limit the indications of lymphadenectomy to stage I grade 1 or 2 tumours and without deep tumours invasion into the myometrium (in that case only 10% of pelvic nodes will be involved). Stage II patients or stage I with grade 3 and/or deep tumour invasion into the myometrium do not require lymphadenectomy as post-operative pelvic external beam irradiation will be performed in all cases. Para-aortic lymphadenectomy is not useful as it increases morbidity and the adjuvant treatment in case of lymph node involvement does not improve the survival rate.
authors.affiliation: Service de Gynécologie-Obstétrique, CHU Bretonneau, Tours.
authors.forename: P
authors.initials: P
authors.lastname: Descamps
authors.forename: G
authors.initials: G
authors.lastname: Body
authors.forename: G
authors.initials: G
authors.lastname: Calais
authors.forename: C
authors.initials: C
authors.lastname: Moire
authors.forename: A
authors.initials: A
authors.lastname: Fignon
authors.forename: O
authors.initials: O
authors.lastname: Jourdain
authors.forename: O
authors.initials: O
authors.lastname: Le Floch
authors.forename: J
authors.initials: J
authors.lastname: Lansac
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D018579:Patient Selection; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome