title: Pericardial effusion and left ventricular function in acute pancreatitis.
abstract: OBJECTIVE
  To establish the prevalence of pericardial effusion and to evaluate left ventricular function in patients with acute pancreatitis.
  
  
  METHODS
  Twenty-one consecutive acute pancreatitis patients were studied. In 15 patients, the pancreatitis was of biliary origin and was attributable to other causes in the remaining six; eight patients had severe pancreatitis and 13 a mild disease. Using M-mode and B-mode echocardiography, pericardial effusion and left ventricular function were evaluated in all of the patients within 48 h of pain onset. All patients underwent an electrocardiogram and a standard chest x-ray. In 12 patients, the same parameters were evaluated 1 month after clinical recovery. Twenty healthy subjects, comparable for sex and age, have been studied as controls.
  
  
  RESULTS
  Left ventricular function was similar in patients with acute pancreatitis and in healthy subjects; it was also similar both in patients with biliary and nonbiliary pancreatitis as well as in patients with severe pancreatitis and in those with mild disease. In the 12 patients in whom echocardiography was performed on hospital admission and one month after clinical recovery, no changes of left ventricular function were observed. Two patients with a mild form and one with a severe disease had pericardial effusion. One patient had negative T waves at electrocardiogram and an apical asynergy at echocardiography; these alterations disappeared after recovery. Chest x-ray revealed pleural effusion in seven patients with severe pancreatitis, whereas no alterations of cardiac silhouette were found. Acute abdominal fluid collections were also detected in seven of eight patients with severe pancreatitis, by contrast-enhanced computed tomography.
  
  
  CONCLUSIONS
  The presence of pericardial effusion or left ventricular asynergy may be observed occasionally at echocardiography in acute pancreatitis patients; these findings, in contrast to the presence of pleural and abdominal effusions, seem to be unrelated to the severity of the disease.
authors.affiliation: Medicina d'Urgenza e Pronto Soccorso, Ospedale S. Orsola, Bologna, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Pezzilli
authors.forename: P
authors.initials: P
authors.lastname: Billi
authors.forename: B
authors.initials: B
authors.lastname: Bertaccini
authors.forename: L
authors.initials: L
authors.lastname: Gullo
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications* / Q000503:physiopathology*; D010490:Pericardial Effusion / Q000209:etiology*; D010996:Pleural Effusion / Q000000981:diagnostic imaging / Q000209:etiology; D013902:Radiography, Thoracic; D016277:Ventricular Function, Left