[An immunologic evaluation of Polish pollen extract Catalet "C" and Catalet "D" in patients with pollinosis].
In a group of 41 hay fever and/or seasonal asthma patients, sensitive to weed or tree pollens the influence of specific immunotherapy (sIT) on the level of IgE, specific IgE and IgG4, and HR induced by anti-IgE and specific allergens was evaluated. It was shown that both allergenic extracts, Catalet C and Catalet D, are really immunogenic, which is manifested in a decrease in specific IgE and in a marked increase in specific IgG4, after 2 years of sIT. In comparison with the placebo, the sensitivity of blood basophils to both specific allergens and non-specific factors significantly decreased.
Chyrek-Borowska
S
S
Kliniki Alergologii Akademii Medycznej w Białymstoku.
Szymański
W
W
Rogalewska
A
A
Michalska
I
I
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000276:immunology / Q000628:therapy*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007167:Immunotherapy; D008297:Male; D008875:Middle Aged; D006109:Poaceae; D011058:Pollen / Q000276:immunology; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000628:therapy*; D014197:Trees; D014612:Vaccines; D014614:Vaccines, Synthetic / Q000276:immunology / Q000627:therapeutic use*
D007074:Immunoglobulin G; D014612:Vaccines; D014614:Vaccines, Synthetic; C082987:catalet; D007073:Immunoglobulin E