Analysis of variables affecting wound healing after musculoskeletal sarcoma resections.
Adjuvant treatment modalities, nutritional parameters, and allogenic blood transfusions are investigated as possible contributing variables which may adversely affect wound healing after tumor resections for musculoskeletal sarcomas. Statistical analysis determined that preoperative chemotherapy, depressed preoperative hematocrit, and allogenic blood transfusions (probably immunosuppression mediated) were the only significant factors affecting wound healing outcome. Suggestions to improve postoperative infection rates are discussed.
Chmell
M J
MJ
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2550, USA.
Schwartz
H S
HS
D000704:Analysis of Variance; D001803:Blood Transfusion; D001859:Bone Neoplasms / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006400:Hematocrit; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000601:surgery*; D009747:Nutritional Physiological Phenomena; D011300:Preoperative Care; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012509:Sarcoma / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000601:surgery*; D013529:Surgical Wound Dehiscence / Q000517:prevention & control; D013530:Surgical Wound Infection / Q000517:prevention & control; D016896:Treatment Outcome; D014945:Wound Healing