[The validation of the use of prostatilen and testilin for treating male infertility].
The paper substantiates the use in clinical setting of medicinal preparations obtaining from prostate and tests, in male infertility. Using male rats for an experimental model of infertility it was shown that prostatilene and testilin exert a stimulating effect on spermatogenesis and androgenic functions of the testis. Those agents appear to correct androgenic-estrogenic balance in the animal organism as a model of infertility. The experiment permitted a conclusion to be drawn to the effect that prostatilene and testilin are liable to be of clinical benefit when used to stimulate spermatogenesis in infertility and hypoandrogenization; besides, the rise in androgens may stimulate copulative function in patients with sexual problems.
Boĭko
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D000818:Animals; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D005303:Fertility Agents, Male / Q000627:therapeutic use*; D007248:Infertility, Male / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D010455:Peptides / Q000627:therapeutic use*; D051381:Rats; D013091:Spermatogenesis / Q000187:drug effects; D013268:Stimulation, Chemical; D013737:Testis / Q000187:drug effects / Q000473:pathology; D013997:Time Factors
D005303:Fertility Agents, Male; D010455:Peptides; C069549:prostatilen; C099451:testilin