Marine and botanical lipids as immunomodulatory and therapeutic agents in the treatment of rheumatoid arthritis.
Fish and plant seed fatty acids have antiinflammatory and immunomodulating properties that make them of potential use in the treatment of rheumatoid arthritis. A better understanding of their effects on the immune system ultimately may lead to the development of more benign therapy for rheumatoid arthritis patients.
DeLuca
P
P
University of Massachusetts Medical Center, Division of Rheumatology, Worcester 10655, USA.
Rothman
D
D
Zurier
R B
RB
D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000378:metabolism / Q000628:therapy*; D002986:Clinical Trials as Topic; D016207:Cytokines / Q000187:drug effects / Q000378:metabolism; D015777:Eicosanoids / Q000378:metabolism; D005395:Fish Oils / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D010938:Plant Oils / Q000494:pharmacology / Q000627:therapeutic use*; D015398:Signal Transduction / Q000187:drug effects
D000276:Adjuvants, Immunologic; D016207:Cytokines; D015777:Eicosanoids; D005395:Fish Oils; D010938:Plant Oils