title: Alpha adrenoceptor gene expression in the rat iris during development and maturity.
abstract: We have examined the developmental profile of the alpha-1 and alpha-2 adrenergic receptor mRNA expression in the rat iris. The expression of the six mRNAs was studied using reverse transcription-polymerase chain reaction. At 4 weeks, the dominant mRNA transcripts in the rat iris were alpha-1B, alpha-1C and alpha-2A. This pattern of alpha adrenoceptor expression was seen from birth, throughout development, and maintained into old age.
authors.affiliation: Division of Neuroscience, John Curtin School of Medical Research, Australian National University, Canberra, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Vidovic
authors.forename: C E
authors.initials: CE
authors.lastname: Hill
mesh_terms: D000818:Animals; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D007498:Iris / Q000254:growth & development / Q000378:metabolism*; D012333:RNA, Messenger / Q000096:biosynthesis; D051381:Rats; D018340:Receptors, Adrenergic, alpha-1 / Q000235:genetics*; D018341:Receptors, Adrenergic, alpha-2 / Q000235:genetics*
chemical_list: D012333:RNA, Messenger; D018340:Receptors, Adrenergic, alpha-1; D018341:Receptors, Adrenergic, alpha-2