title: Anal pathology in patients with Crohn's disease.
abstract: BACKGROUND
  A distinctive feature of patients suffering from Crohn's disease is a predisposition to develop a variety of anal complications. The aetiology of such conditions is unclear, and the reported incidence of anal involvement in Crohn's disease varies party due to the various criteria used for classification. This study aims to review the management of patients with symptomatic anal pathology associated with Crohn's disease at St Vincent's Hospital, Melbourne.
  
  
  METHODS
  A database of 306 patients with Crohn's disease referred to the department between January 1978 and October 1994 was reviewed to identify those patients with symptomatic anal disease. The anal pathology was recorded and classified. Demographic data and the clinical and surgery history of the patient were recorded.
  
  
  RESULTS
  Of the 306 patients with Crohn's disease, 129 (42.4%) were identified as having symptomatic anal pathology. Patients were likely to present with anal symptoms after they had been diagnosed as having intestinal Crohn's disease (46.1%). The commonest presentations were perianal abscess (29.5%), anal fissure (27.6%), and low anal fistula (26.7%). A minority of patients presented with high/complex anal fistulae (3.8%), or recto-vaginal fistulae (5.2%). Five per cent of patients had Crohn's disease localized to the anal area. The pattern of intestinal disease in the remaining patients was small bowel 21.1%. small bowel and colon 31.9%, and colon 43.0%. A total of 244 local anal and surgical procedures were performed on these patients; the commonest of these were drainage of an abscess (38.5%), examination under anaesthetic (29.1%), and laying open of a low anal fistula (22.5%). Following surgical treatment, the recurrence rate for perianal abscesses was 13%, and for low anal fistulae 6%.
  
  
  CONCLUSIONS
  The majority of patients with Crohn's disease who develop anal pathology have an excellent prognosis. A minority of patients develop complex anal complex anal fistulae and these remain a therapeutic challenge.
authors.affiliation: Department of Colon and Rectal Surgery, St. Vincent's Hospital, Victoria Parade, Melbourne, Australia.
authors.forename: C
authors.initials: C
authors.lastname: Platell
authors.forename: J
authors.initials: J
authors.lastname: Mackay
authors.forename: B
authors.initials: B
authors.lastname: Collopy
authors.forename: R
authors.initials: R
authors.lastname: Fink
authors.forename: P
authors.initials: P
authors.lastname: Ryan
authors.forename: R
authors.initials: R
authors.lastname: Woods
mesh_terms: D000328:Adult; D001003:Anal Canal / Q000473:pathology* / Q000601:surgery; D001004:Anus Diseases / Q000473:pathology* / Q000601:surgery; D003424:Crohn Disease / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005260:Female; D005402:Fistula / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012006:Rectovaginal Fistula / Q000473:pathology; D012189:Retrospective Studies; D016896:Treatment Outcome