title: Electron microscopic study on interodontoblastic collagen fibrils in amputated canine dental pulp.
abstract: The purpose of this research was to study the presence and the ultrastructural features of interodontoblastic collagen fibrils and their contribution to the formation of reparative dentin in dog incisors and premolars for a period of 30 days following experimental pulpotomy. On the seventy day after pulp exposure and capping with calcium hydroxide, short cylindrical-shaped cells collected at the coronal end of the vital pulp tissue. Many collagen fibrils were synthesized in the intercellular spaces and in the direction of the long axis of these cells. On the fourteenth day, large bundles of collagen fibrils were observed in the intercellular spaces of young odontoblasts. These bundles spread out in a fan-shaped arrangement. On the thirtieth day, the odontoblasts formed a tubular dentin matrix. Small numbers of twisted collagen bundles crossed the distal junctional complex of the odontoblast cell bodies and entered the dentin matrix.
authors.affiliation: Department of Endodontology and Periodontology, Hiroshima University School of Dentistry, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Higashi
authors.forename: H
authors.initials: H
authors.lastname: Okamoto
mesh_terms: D000818:Animals; D003094:Collagen / Q000648:ultrastructure*; D003782:Dental Pulp / Q000502:physiology* / Q000648:ultrastructure; D003809:Dentin, Secondary / Q000254:growth & development* / Q000648:ultrastructure; D003810:Dentinogenesis; D004285:Dogs; D005109:Extracellular Matrix / Q000648:ultrastructure; D005110:Extracellular Space; D008854:Microscopy, Electron; D009804:Odontoblasts / Q000648:ultrastructure; D011672:Pulpotomy; D014945:Wound Healing / Q000502:physiology
chemical_list: D003094:Collagen