title: Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome: spontaneous remission in a 15-year-old girl.
abstract: Acanthosis nigricans is associated with many diseases, including internal malignancies, genetic disorders, and endocrine abnormalities. Insulin resistance frequently accompanies endocrine-associated acanthosis nigricans. We describe a patient with acanthosis nigricans associated with hyperandrogenism and extreme insulin resistance that spontaneously resolved after a marked decrease in insulin receptor antibodies.
authors.affiliation: University of South Florida College of Medicine, Tampa 33612, USA.
authors.forename: L E
authors.initials: LE
authors.lastname: Esperanza
authors.forename: N A
authors.initials: NA
authors.lastname: Fenske
mesh_terms: D000052:Acanthosis Nigricans / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D000293:Adolescent; D005260:Female; D006801:Humans; D017588:Hyperandrogenism / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D007333:Insulin Resistance; D012075:Remission, Spontaneous; D012867:Skin / Q000473:pathology; D013577:Syndrome