title: [Levels of interleukin-2 )IL-2 and tumor necrosis factor alpha (TNF-alpha) mRNA in aged rat spleen under physiological conditions and in septic shock: possible role of pidotimod in gene expression modulation].
authors.affiliation: Istituto di Medicina Interna, Università degli Studi di Milano, Italia.
authors.forename: B
authors.initials: B
authors.lastname: Arosio
authors.forename: D
authors.initials: D
authors.lastname: Santambrogio
authors.forename: N
authors.initials: N
authors.lastname: Gagliano
authors.forename: G
authors.initials: G
authors.lastname: Annoni
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000375:Aging / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D000818:Animals; D004927:Escherichia coli Infections / Q000276:immunology* / Q000378:metabolism; D005786:Gene Expression Regulation / Q000187:drug effects*; D007376:Interleukin-2 / Q000096:biosynthesis* / Q000235:genetics; D008297:Male; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D012333:RNA, Messenger / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012772:Shock, Septic / Q000276:immunology* / Q000378:metabolism; D013154:Spleen / Q000737:chemistry* / Q000187:drug effects / Q000473:pathology; D013268:Stimulation, Chemical; D013844:Thiazoles / Q000494:pharmacology*; D053778:Thiazolidines; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D000276:Adjuvants, Immunologic; D007376:Interleukin-2; D012333:RNA, Messenger; D013844:Thiazoles; D053778:Thiazolidines; D014409:Tumor Necrosis Factor-alpha; C064893:pidotimod; D011761:Pyrrolidonecarboxylic Acid