In vitro and in vivo investigation of anticomplement agents FUT-175 and K76COOH, in the prevention of hyperacute rejection following discordant xenotransplantation in a nonhuman primate model.
Kobayashi
T
T
Oklahoma Transplantation Institute, Oklahoma City 73112, USA.
Neethling
F A
FA
Koren
E
E
Taniguchi
S
S
Ye
Y
Y
Niekrasz
M
M
Takagi
H
H
Hancock
W W
WW
Cooper
D K
DK
D000818:Animals; D001550:Benzamidines; D002478:Cells, Cultured; D003169:Complement Inactivator Proteins / Q000494:pharmacology*; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control*; D006085:Graft Survival; D006146:Guanidines / Q000494:pharmacology*; D006877:Hydroxamic Acids / Q000494:pharmacology*; D007668:Kidney / Q000276:immunology; D016030:Kidney Transplantation / Q000276:immunology; D010215:Papio; D012717:Sesquiterpenes / Q000494:pharmacology*; D013552:Swine
D001550:Benzamidines; D003169:Complement Inactivator Proteins; D006146:Guanidines; D006877:Hydroxamic Acids; D012717:Sesquiterpenes; C003486:2-methyl-3-(4-phenylpiperidino)propionohydroxamic acid hydrochloride; C038797:K 76 carboxylic acid; C032855:nafamostat