title: Palliative treatment for tetralogy of Fallot with percutaneous balloon dilatation of right ventricular outflow tract.
abstract: Percutaneous balloon pulmonary dilatation of the right ventricular tract was performed on 16 children with tetralogy of Fallot for palliative purposes after routine cardiac catheterization. Immediate improvement in aortic saturation from 73.4 +/- 6.8 to 84.0 +/- 4.8% (mean +/- SD = 10.6 +/- 2.7%, p < 0.001) and clinical symptoms were achieved in all 16 cases. The pressures in the right ventricle, pulmonary artery, left ventricle and aorta showed no remarkable changes after percutaneous balloon dilatation. The diameters of the proximal end and at the first branching of the right and left pulmonary arteries, pulmonary arterial index and the diameter of the descending aorta at the diaphragm increased significantly after balloon dilatation (p value 0.0004-0.006). One child suffered from repeated cyanotic spells in spite of the immediate improvement of aortic saturation. She received a left side Blalock-Taussig shunt 2 months after the balloon dilatation. None of the children had a significant complication. Eight had follow-up cardiac catheterization one year later and demonstrated much improvement in the diameters of the proximal end and at the first branching of the right and left pulmonary arteries, pulmonary arterial index and the diameter of the descending aorta at the diaphragm (p value 0.005-0.04). All 8 patients had their cardiac lesions successfully corrected. Percutaneous balloon dilatation is an alternative palliative therapy for children with tetralogy of Fallot.
authors.affiliation: Department of Pediatrics, Veterans General Hospital-Taipei, Taiwan, ROC.
authors.forename: B
authors.initials: B
authors.lastname: Hwang
authors.forename: J H
authors.initials: JH
authors.lastname: Lu
authors.forename: B C
authors.initials: BC
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Hsieng
authors.forename: C C
authors.initials: CC
authors.lastname: Meng
mesh_terms: D006328:Cardiac Catheterization; D002404:Catheterization; D002675:Child, Preschool; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D010166:Palliative Care; D011651:Pulmonary Artery / Q000473:pathology / Q000503:physiopathology; D013771:Tetralogy of Fallot / Q000503:physiopathology / Q000628:therapy*; D014694:Ventricular Outflow Obstruction / Q000503:physiopathology / Q000628:therapy*