title: Acute exposure to carbon monoxide does not affect plasma lipids, lipoproteins, and apolipoproteins.
abstract: OBJECTIVE
  To examine the effects of acute exposure to carbon monoxide and hypoxia on plasma lipids, lipoproteins, and apolipoproteins.
  
  
  METHODS
  Random-order assignment to blinded, inhaled exposures of carbon monoxide and hypoxia.
  
  
  METHODS
  Research laboratory of ambulatory subjects.
  
  
  METHODS
  10 elderly, male nonsmokers with chronic stable angina.
  
  
  METHODS
  Random-order two-hour inhaled exposure to clean air at sea level, carbon monoxide at sea level, carbon monoxide at high altitude, and clean air at high altitude.
  
  
  METHODS
  Fasting plasma lipids, lipoproteins, and apolipoproteins before and after exposures.
  
  
  RESULTS
  No differences were noted between fasting plasma lipid, lipoprotein, or apolipoprotein levels before and after exposures.
  
  
  CONCLUSIONS
  Acute exposure to carbon monoxide and high altitude does not affect fasting plasma lipid, lipoprotein, or apolipoprotein levels.
authors.affiliation: Department of Medicine, School of Medicine, University of California, Los Angeles, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Leaf
authors.forename: M T
authors.initials: MT
authors.lastname: Kleinman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000531:Altitude; D000787:Angina Pectoris / Q000097:blood / Q000150:complications; D001053:Apolipoproteins / Q000097:blood*; D002248:Carbon Monoxide / Q000494:pharmacology; D002249:Carbon Monoxide Poisoning / Q000097:blood* / Q000150:complications; D003327:Coronary Disease / Q000139:chemically induced; D006801:Humans; D000860:Hypoxia / Q000097:blood* / Q000139:chemically induced / Q000150:complications; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D001053:Apolipoproteins; D008055:Lipids; D008074:Lipoproteins; D002248:Carbon Monoxide