title: Efficacy of P6 acupressure in the treatment of nausea and vomiting during pregnancy.
abstract: OBJECTIVE
  Our purpose was to investigate the efficacy of P6 acupressure in reducing or relieving symptoms of nausea with or without vomiting and retching during pregnancy.
  
  
  METHODS
  Symptomatic pregnant volunteers (n=161) participated in a 7-day community-based clinical trial. All participants were assigned to one of three groups (i.e., P6 acupressure, placebo [acupressure bands inappropriately placed], or control) on the basis of a process of blocked randomization. Data were analyzed by error bar charts and analysis of variance of difference scores.
  
  
  RESULTS
  Of 161 women, 149 (92.5%) completed the protocol. Irrespective of group assignment, participants reported significant decreases in nausea (p<0.0009) and vomiting or retching (p<0.0009). However, there was no differential treatment effect as a result of acupressure.
  
  
  CONCLUSIONS
  There was no apparent medical benefit from the use of P6 acupressure. Our findings differ from other recently published studies that did not include a control group.
authors.affiliation: Faculty of Nursing, University of Alberta, Edmonton, Canada.
authors.forename: B
authors.initials: B
authors.lastname: O'Brien
authors.forename: M J
authors.initials: MJ
authors.lastname: Relyea
authors.forename: T
authors.initials: T
authors.lastname: Taerum
mesh_terms: D019050:Acupressure; D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D009325:Nausea / Q000628:therapy*; D010298:Parity; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D014839:Vomiting / Q000628:therapy*