title: Neuromuscular manifestations of diarrhea related hypokalemia.
abstract: Twenty-three children from 8-60 months (mean age 21.13 months) admitted with neuromuscular manifestations of diarrhea related hypokalemia were studied. Forty four per cent cases were suffering from diarrhea at the time of admission but in majority of cases (56%), the diarrheal episode had already terminated. Mild hypokalemia was seen in 17.4%, moderate in 43.5% and severe in 39.1%. Neck flop was the commonest (100%) neuromuscular manifestations followed by diminished bowel sounds (82.6%), truncal weakness (52.2%), weakness of limbs (52.2%), lethargy (43. 5%), abdominal distension (43.5%), respiratory involvement (4.3%) and phantom hernia (4.3%). Two cases (8.7%) had flaccid paralysis of both the lower limbs. Severe hypokalemia was more frequently observed in children below 24 months of age and those who had received i.v. fluids or salt sugar solution before reporting in the hospital. A significant correlation was noticed between severity of hypokalemia and frequency of stools (p < 0.05), degree of dehydration (p < 0.01), severity of nutrition (p < 0.01) and extent of neuromuscular involvement (p < 0.01). Our results highlights the importance of diarrhea related hypokalemia particularly in young malnourished children who are rehydrated with solutions inadequate in potassium. Early diagnosis and appropriate treatment can promptly reverse these manifestations within 48-72 hours.
authors.affiliation: Department of Pediatrics, Lady Hardinge Medical College, New Delhi.
authors.forename: A
authors.initials: A
authors.lastname: Chhabra
authors.forename: A K
authors.initials: AK
authors.lastname: Patwari
authors.forename: S
authors.initials: S
authors.lastname: Aneja
authors.forename: J
authors.initials: J
authors.lastname: Chandra
authors.forename: V K
authors.initials: VK
authors.lastname: Anand
authors.forename: T P
authors.initials: TP
authors.lastname: Ahluwalia
mesh_terms: D002675:Child, Preschool; D003967:Diarrhea / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007008:Hypokalemia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D007223:Infant; D008297:Male; D018908:Muscle Weakness / Q000209:etiology / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D011188:Potassium / Q000097:blood / Q000627:therapeutic use; D011379:Prognosis
chemical_list: D011188:Potassium