title: Different action of xenoreactive natural and immune antibodies on functioning cardiomyocytes.
abstract: PNAB and IAB have totally different action on BCM. PNAB inhibit the contractile function of BCM by producing a reversible standstill and by disturbing the synchronization of the BCM-monolayer. IAB are cytotoxic and depend on the presence of complement.
authors.affiliation: Institute for Surgical Research, Grosshadern, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Autenrieth
authors.forename: U
authors.initials: U
authors.lastname: Müller-Werdan
authors.forename: B
authors.initials: B
authors.lastname: Koidl
authors.forename: K
authors.initials: K
authors.lastname: Werdan
authors.forename: C
authors.initials: C
authors.lastname: Hammer
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000906:Antibodies / Q000276:immunology*; D000910:Antibodies, Heterophile / Q000276:immunology*; D002478:Cells, Cultured; D003165:Complement System Proteins / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D006321:Heart / Q000502:physiology; D006801:Humans; D007700:Kinetics; D009200:Myocardial Contraction; D009206:Myocardium / Q000276:immunology*; D051381:Rats; D013997:Time Factors
chemical_list: D000906:Antibodies; D000910:Antibodies, Heterophile; D003165:Complement System Proteins