Promoter region of the rat phosphoribosylpyrophosphate synthetase-associated protein 39.
The 5' region of the 39-kDa rat phosphoribosylpyrophosphate synthetase-associated protein (PAP39) gene was isolated and sequenced. The promoter region of the rat PAP39 is GC-rich and contains potential binding sites for regulatory factors. Its promoter activity was demonstrated by transfection of the promoter region in fusion with the chloramphenicol acetyltransferase gene into rat pheochromocytoma PC12 cell.
Ishizuka
T
T
Department of Biochemistry, Chiba University, School of Medicine, Japan.
Sawa
K
K
Kita
K
K
Ino
H
H
Sonoda
T
T
Suzuki
N
N
Tatibana
M
M
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D018076:DNA, Complementary / Q000235:genetics; D005796:Genes; D017930:Genes, Reporter; D008099:Liver / Q000378:metabolism; D008969:Molecular Sequence Data; D016716:PC12 Cells; D011401:Promoter Regions, Genetic; D011506:Proteins / Q000235:genetics*; D051381:Rats; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D014162:Transfection
D018076:DNA, Complementary; C086305:PAP39; D011506:Proteins; D011993:Recombinant Fusion Proteins