Safety and efficacy of Xenetix, a new iodinated contrast agent, in pediatric angiocardiography.
OBJECTIVE
The aim of this work was to study the safety and efficacy of iobitridol 350 in pediatric angiocardiography compared to iopamidol 370.


METHODS
40 children participated in each test group. Each examination was rated as diagnostic or nondiagnostic and the image quality was noted. Nature,onset,intensity as well as outcome of each adverse reaction was reported.


RESULTS
There was no significant difference in either image quality or clinical safety between the 2 groups.


CONCLUSIONS
Iobitridol is a safe and effective contrast agent for pediatric angiocardiography.
Rossignol
A M
AM
Department of Pediatrics, Central Hospital, Grenoble, France.
Lusson
J R
JR
Chantepie
A
A
Losay
J
J
D000790:Angiocardiography; D002648:Child; D003287:Contrast Media / Q000009:adverse effects; D004311:Double-Blind Method; D004562:Electrocardiography / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007472:Iohexol / Q000009:adverse effects / Q000031:analogs & derivatives*; D007479:Iopamidol / Q000009:adverse effects
D003287:Contrast Media; C093233:iobitridol; D007472:Iohexol; D007479:Iopamidol