[Japanese encephalitis in citizens of Russia who travel abroad].
Typical and atypical forms of Japanese encephalitis (JE) in the Russians visiting Asian countries endemic for JE are described. A patient who contracted the disease in China developed 5 months after returning to Russia acute meningoencephalitis with mental disorders and a lethal outcome on day 5 with bulbar symptoms. JE virus (strain SP-69) was isolated from his brain. By antigenic and genetic properties this strain occupies an intermediate position between Jagar-01 and Nakayama serotypes. A pregnant woman (6 months gestation) who lived in Birma for 3 years suffered from encephalitis running a protracted (more than 6 months) course; mildly manifest pyramidal signs were detected in her one-year-old infant with a normal mental status. Serologic studies showed that the disease was caused by infection with Jagar-01 serotype of JE virus. A patient contracting the disease 1 month after arrival in Japan developed a recurrent pattern of the illness: the diagnosis of JE was confirmed by repeated detection of virus-neutralizing anti-bodies in the blood and liquor. None of the patients was vaccinated against JE. Indications to prophylactic vaccination of subjects leaving for countries endemic for JE are discussed.
Pogodina
V V
VV
Bochkova
N G
NG
Leshchinskaia
E V
EV
Levina
L S
LS
D002681:China / Q000453:epidemiology; D004664:Encephalitis Virus, Japanese / Q000145:classification / Q000302:isolation & purification; D004672:Encephalitis, Japanese / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012426:Russia / Q000453:epidemiology; D014195:Travel
Iaponskiĭ éntsefalit u grazhdan Rossii, vyezzhaiushchikh za rubezh.