[The importance of interleukin 6 (IL-6) in pathogenesis and diagnosis of renal glomerular diseases].
IL-6 synthesized by various types of cells and has multiple biological functions. In the kidney, IL-6 is synthesized by mesangial cells and acts as an autocrine growth factor. IL-6 was demonstrated in the glomerular mesangium and in the urine of patients with proliferative glomerulonephritis, suggesting that it has an important role in the pathogenesis of renal glomerular diseases.
Kacprzyk
F
F
Klinika Nefrologiczna Instytutu Medycyny Wewnetrznej Akademii Medycznej w Lodzi.
D015432:Glomerulonephritis, Membranoproliferative / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D015850:Interleukin-6 / Q000502:physiology* / Q000652:urine
D015850:Interleukin-6
Znaczenie interleukiny 6 (IL-6) w patogenezie i diagnostyce kłebuszkowych chorób nerek.