[The status of malaria chemoresistance in Africa].
Chloroquine resistance of Plasmodium falciparum in Africa emerged two decades ago. Today, this resistance is wide-spread to the whole african continent and other resistances have appeared since. Mechanisms of resistance to lysosomotropes and to antimetabolites are described here, as also the epidemiology of these resistances in 1994.
Le Bras
J
J
Centre National de Référence du Paludisme, Hôpital Bichat-Claude Bernard, Paris, France.
D000349:Africa / Q000453:epidemiology; D000962:Antimalarials / Q000145:classification / Q000494:pharmacology / Q000627:therapeutic use*; D004351:Drug Resistance; D005602:France / Q000208:ethnology; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy* / Q000453:epidemiology
D000962:Antimalarials
La situation des chimiorésistances du paludisme en Afrique.