title: Age-standardized incidence and prevalence of Parkinson's disease in a Swedish community.
abstract: Parkinson's disease (PD) shows a geographical variation. All prescriptions for anti-parkinsonian drugs were recorded for a half-year in a region with low L-dopa consumption. Hospital and outpatient records were studied and physicians were asked to supply details of PD patients in the region, with 147,777 inhabitants. The crude prevalence was 115 PD per 100,000 inhabitants, based on 170 cases. In contrast to other studies we report an age-standardized prevalence, which was 76 per 100,000, using the European Standard Population as reference. The corresponding approximate incidences were 11.0 (crude) and 7.9 (age-standardized) per 100,000 person-years. Male preponderance appeared in all age groups. Mean age at onset was 65.6 years, the highest figure reported. Variation between studies for age at onset, differences in prevalence, and male preponderance suggest environmental risk factors to be of importance for PD.
authors.affiliation: Department of Geriatrics, University Hospital, Linköping, Sweden.
authors.forename: P A
authors.initials: PA
authors.lastname: Fall
authors.forename: O
authors.initials: O
authors.lastname: Axelson
authors.forename: M
authors.initials: M
authors.lastname: Fredriksson
authors.forename: G
authors.initials: G
authors.lastname: Hansson
authors.forename: B
authors.initials: B
authors.lastname: Lindvall
authors.forename: J E
authors.initials: JE
authors.lastname: Olsson
authors.forename: A K
authors.initials: AK
authors.lastname: Granérus
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000978:Antiparkinson Agents / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D004363:Drug Utilization; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D012737:Sex Factors; D013548:Sweden / Q000453:epidemiology
chemical_list: D000978:Antiparkinson Agents