title: [The interferon system in acute tick-borne encephalitis and effect on the dynamics of clinical laboratory indicators using different methods of interferon therapy].
abstract: Study of the interferon system parameters, natural killer activity, and immunologic characteristics in patients with acute tick-borne encephalitis confirmed that addition of interferon preparations to combined therapy is pathogenetically justified. Reaferon was conducive to shortening of the manifest period of the disease and to alleviation of its symptoms, but it depressed its own interferonogenesis. Viferon had not only a positive impact on the time course of clinical parameters, but promoted a more active recovery of interferon production and immunologic parameters.
authors.forename: V V
authors.initials: VV
authors.lastname: Malinovskaia
authors.forename: G M
authors.initials: GM
authors.lastname: Volegova
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Ustinova
mesh_terms: D000208:Acute Disease; D004675:Encephalitis, Tick-Borne / Q000097:blood* / Q000628:therapy; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D007372:Interferons / Q000097:blood* / Q000276:immunology; D011994:Recombinant Proteins
chemical_list: D007370:Interferon Type I; D011994:Recombinant Proteins; D007372:Interferons
vernacular_title: Sistema interferona pri ostrom kleshchevom éntsefalite i vliianie na dinamiku kliniko-laboratornykh pokazateleĭ razlichnykh metodov interferonoterapii.