[Development of an optimal scheme for calculating results of the use of an immunoenzyme test-system for determining the antigenic activity of a cultured antirabies vaccine].
Ninety-eight lots of commercial antirabies vaccine manufactured by Immunopreparat Research and Production Amalgamation have been tested using enzyme immunoassay system for the detection of rabies virus antigens. Comparison of different variants of interpreting and expressing the results helped define the optimal method for assessment of vaccine titer and reference values: optical density value equal to 0.2 is taken as the cut-off. Antigenic activity of the vaccine may be expressed in international units, similarly as immunogenic activity.
Tsetlin
E M
EM
Volkova
R A
RA
D000956:Antigens, Viral / Q000032:analysis* / Q000276:immunology; D007124:Immunoenzyme Techniques; D011819:Rabies Vaccines / Q000276:immunology*
D000956:Antigens, Viral; D011819:Rabies Vaccines
Otrabotka optimal'noĭ skhemy ucheta rezul'tatov pri primenenii immunofermentnoĭ test-sistemy dlia opredeleniia antigennoĭ aktivnosti kul'tural'noĭ antirabicheskoĭ vaktsiny.