title: Sensitization to para-tertiary-butylphenolformaldehyde resin.
abstract: BACKGROUND
  Phenolformaldehyde resins, especially the para-tertiary-butylphenolformaldehyde resin (PTBP-FR), are widely used in industry and in numerous materials of everyday use, such as glues, adhesives, or inks. They can cause many occupational and nonoccupational cases of dermatitis.
  
  
  METHODS
  Forty-one patients with positive patch test results to PTBP-FR were selected for this study. They were patch-tested with a series of chemically related compounds and cross-reactions were noted.
  
  
  RESULTS
  Phenolformaldehyde resin (PF-R) was frequently positive (65.8%), whereas other compounds gave a much smaller number of positive results. Cases of occupational exposure (24.4%), location of the dermatitis (hands were involved in 46.3% of cases), and possible sources of exposure (shoes were the responsible agent in 12.2% of cases) were evaluated.
  
  
  CONCLUSIONS
  Phenolformaldehyde resins are an important cause of contact dermatitis and must be studied chemically and clinically to improve the prognosis of sensitized patients.
authors.affiliation: Department of Dermatology, Galliera Hospital, Genoa, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Massone
authors.forename: A
authors.initials: A
authors.lastname: Anonide
authors.forename: S
authors.initials: S
authors.lastname: Borghi
authors.forename: D
authors.initials: D
authors.lastname: Usiglio
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000485:Allergens / Q000276:immunology*; D002648:Child; D003429:Cross Reactions / Q000276:immunology; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000276:immunology; D009783:Dermatitis, Occupational / Q000175:diagnosis / Q000276:immunology; D005260:Female; D005500:Follow-Up Studies; D005557:Formaldehyde / Q000009:adverse effects; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D012117:Resins, Synthetic / Q000009:adverse effects*
chemical_list: D000485:Allergens; D012117:Resins, Synthetic; D005557:Formaldehyde; C014273:p-tert-butylphenolformaldehyde resin