title: Intrauterine insemination: evaluation of the results according to the woman's age, sperm quality, total sperm count per insemination and life table analysis.
abstract: We report on 332 infertile couples who underwent 1115 cycles of intrauterine insemination (IUI) with washed husband's semen. The indication for IUI was an abnormal post-coital test due to either a male or cervical infertility factor. The mean number of IUI cycles per patients was 3.4, the overall pregnancy rate 18.7%, and the pregnancy rate per cycle 5.6%. The cumulative pregnancy rate calculated by life table analysis showed that 16.0% of pregnancies occurred in the first three treatment cycles, while the cumulative pregnancy rate was 26.9% by the sixth cycle. The outcome of the therapy was adversely affected if the woman's age was > 39 years and/or total motile sperm count per insemination was < 1 x 10(6). No pregnancy occurred in women older than 44 years or in cases with a total motile sperm count before semen preparation of < 1 x 10(6).
authors.affiliation: Department of Obstetrics and Gynaecology, Hospital Cantonal University of Geneva, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Campana
authors.forename: D
authors.initials: D
authors.lastname: Sakkas
authors.forename: A
authors.initials: A
authors.lastname: Stalberg
authors.forename: P G
authors.initials: PG
authors.lastname: Bianchi
authors.forename: I
authors.initials: I
authors.lastname: Comte
authors.forename: T
authors.initials: T
authors.lastname: Pache
authors.forename: D
authors.initials: D
authors.lastname: Walker
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D007246:Infertility / Q000628:therapy*; D007317:Insemination, Artificial, Homologous / Q000592:standards*; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D013076:Sperm Count; D013081:Sperm Motility
chemical_list: D006728:Hormones