Long-term survival after resection for advanced gastric carcinoma.
Although several prognostic indicators for gastric carcinoma have been reported, characteristics of long-term survivors with advanced gastric carcinoma have not yet been clarified. We compared clinicopathologic features of 54 patients who survived for >10 years after resection for advanced gastric carcinoma with those of 72 patients who died of recurrence. Long-term survivors were characterized by small tumor size (6.2 cm vs. 8.1 cm, p < 0.01), negative serosal invasion (50% vs. 32%, p < 0.05), few lymph node metastases (fewer than seven) (89% vs. 56%, p < 0.01), limited lymph node metastases (nO, nl) (89% vs. 40%, p < 0.01), and earlier stage (I or II) (50% vs. 16%, p < 0.01). These results indicate that small tumor size, negative serosal invasion, and fewer than seven positive nodes were the predictors of long-term survival after resection for advanced gastric carcinoma.
Adachi
Y
Y
Second Department of Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Mori
M
M
Maehara
Y
Y
Sugimachi
K
K
D000230:Adenocarcinoma / Q000401:mortality* / Q000473:pathology / Q000556:secondary / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D015996:Survival Rate