Successful treatment of intraoperative malignant hyperthermia during renal transplantation.
Malignant hyperthermia is a complication of general anesthesia that is especially problematic if it occurs during renal transplantation because myoglobinemia, shock, and ischemia play a role in injuring the transplanted kidney. In this report, we describe a case of malignant hyperthermia, its clinical course, and the measures taken to successfully treat it and preserve the function of a kidney allograft.
Goss
J A
JA
Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Brennan
D C
DC
Miller
B T
BT
Shenoy
S
S
McClure
S
S
Howard
T K
TK
Flye
M W
MW
D000328:Adult; D000768:Anesthesia, General / Q000009:adverse effects; D003620:Dantrolene / Q000627:therapeutic use; D006801:Humans; D007431:Intraoperative Complications / Q000628:therapy*; D007511:Ischemia / Q000503:physiopathology; D007668:Kidney / Q000503:physiopathology; D016030:Kidney Transplantation / Q000009:adverse effects / Q000502:physiology; D008297:Male; D008305:Malignant Hyperthermia / Q000503:physiopathology / Q000628:therapy*; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D009211:Myoglobin / Q000097:blood; D006435:Renal Dialysis; D012769:Shock / Q000503:physiopathology; D014184:Transplantation, Homologous; D016896:Treatment Outcome
D009125:Muscle Relaxants, Central; D009211:Myoglobin; D003620:Dantrolene