title: Comparison of diagnostic performance with ventilation-perfusion lung imaging in different patient populations.
abstract: OBJECTIVE
  To determine if patient age, chest radiographic abnormalities, or history of cardiopulmonary disease or venous thromboembolism affected diagnostic performance with ventilation-perfusion (V-P) imaging.
  
  
  METHODS
  Receiver operating characteristic (ROC) analyses were performed on the final V-P imaging interpretation data obtained during the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study. Diagnostic performance with V-P imaging was not substantially different in patients with varying ages, an abnormal chest radiograph, or a history of venous thromboembolism or cardiopulmonary disease.
  
  
  CONCLUSIONS
  Because diagnostic performance with V-P imaging in detection of pulmonary embolism was similar among the patient populations examined, an abnormal chest radiograph or history of venous thromboembolism or cardiopulmonary disease does not appear to adversely affect overall diagnostic performance in evaluation of acute pulmonary embolism.
authors.affiliation: Department of Radiology, Hospital of the University og Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: D F
authors.initials: DF
authors.lastname: Worsley
authors.forename: A
authors.initials: A
authors.lastname: Alavi
authors.forename: H I
authors.initials: HI
authors.lastname: Palevsky
authors.forename: H L
authors.initials: HL
authors.lastname: Kundel
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D006331:Heart Diseases / Q000453:epidemiology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008171:Lung Diseases / Q000453:epidemiology; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging* / Q000453:epidemiology; D012372:ROC Curve; D011859:Radiography; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013924:Thrombophlebitis / Q000453:epidemiology; D014692:Ventilation-Perfusion Ratio