title: Repair of postinfarction ventricular septal defect on a beating heart.
abstract: Two elderly patients with postinfarction ventricular septal defect underwent repair by endocardial patch with infarct exclusion on a beating heart under normothermic cardiopulmonary bypass with ultra-short-acting beta-blocker infusion. Their hemodynamic states soon recovered, and postoperative angiographic studies showed improvement of cardiac function and no residual shunt. Ultra-short-acting beta-blocker has the potential to facilitate safe repair of postinfarction ventricular septal defect on a beating heart, and this operative approach can be beneficial for myocardial protection.
authors.affiliation: First Department of Surgery, Osaka University, Medical School, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: K
authors.initials: K
authors.lastname: Kadoba
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Sawa
authors.forename: H
authors.initials: H
authors.lastname: Imagawa
authors.forename: T
authors.initials: T
authors.lastname: Masai
authors.forename: H
authors.initials: H
authors.lastname: Matsuda
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D001831:Body Temperature; D002315:Cardiopulmonary Bypass; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000150:complications*; D011412:Propanolamines / Q000627:therapeutic use; D012770:Shock, Cardiogenic / Q000601:surgery; D018658:Ventricular Septal Rupture / Q000601:surgery*
chemical_list: D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; C036604:esmolol