title: Comparative performance for immediate hypersensitivity skin testing using two skin prick test devices.
abstract: Fifty-five patients were skin-tested by Multi-Test (M) and needle prick test (NPT) to compare the reproducibility of the methods. We used 6 allergenic extracts: Dermatophagoides pteronyssinus, Dermatophagoides farinae, dog epithelium, cat pelt, American cockroach and mixed molds. A glycerosaline and a positive control (histamine 1 mg/ml) were performed in both methods. Statistically significant differences in histamine and Dermatophagoides farinae wheal reactions between the two methods (M > NPT) were found, with no differences with the other allergenic extracts. We concluded that the two methods are similar with respect to determining the immediate hypersensitivity, but the Multi-Test is better accepted by children.
authors.affiliation: Division of Allergy, Clinical Immunology and Rheumatology, Federal University of São Paulo, Brazil.
authors.forename: M C
authors.initials: MC
authors.lastname: Rizzo
authors.forename: C K
authors.initials: CK
authors.lastname: Naspitz
authors.forename: D
authors.initials: D
authors.lastname: Solé
mesh_terms: D000293:Adolescent; D000485:Allergens / Q000276:immunology; D001249:Asthma / Q000175:diagnosis; D002648:Child; D005260:Female; D006632:Histamine / Q000276:immunology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis*; D008297:Male; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis; D012882:Skin Tests / Q000379:methods*
chemical_list: D000485:Allergens; D006632:Histamine