title: Dementia and Down syndrome.
abstract: Through deinstitutionalization, more adults with mental retardation are living in the community under the care of family physicians. Patients with Down syndrome are at high risk for early Alzheimer's disease. This case report describes a 43-year-old woman with Down syndrome whose progressive functional decline over 3 years was attributed to dementia of the Alzheimer type.
authors.affiliation: Family Practice Residency, Fairview Health Systems, Cleveland, Ohio, USA.
authors.forename: C V
authors.initials: CV
authors.lastname: Tyler
authors.forename: J C
authors.initials: JC
authors.lastname: Shank
mesh_terms: D000328:Adult; D000544:Alzheimer Disease / Q000150:complications*; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002746:Chlorpromazine / Q000627:therapeutic use; D018450:Disease Progression; D004314:Down Syndrome / Q000150:complications*; D004830:Epilepsy, Tonic-Clonic / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans
chemical_list: D014150:Antipsychotic Agents; D002746:Chlorpromazine