[Effects of antioxidant state on individual susceptibility to silicosis (an experimental study)].
The authors proved that animals having higher natural antioxidant activity and lower intensity of lipid peroxidation are more resistant to fibrogenic effects of quartz. The peritoneal macrophages obtained from those animals show higher resistance to quartz exposure "in vitro". Parameters characterizing antioxidant system should be included into a group of indexes describing propensity to silicosis.
Kislitsina
N S
NS
Katsnel'son
B A
BA
Privalova
L I
LI
Driakhlova
O V
OV
D000818:Animals; D000975:Antioxidants; D002478:Cells, Cultured; D004198:Disease Susceptibility; D015227:Lipid Peroxidation; D008264:Macrophages / Q000187:drug effects; D008297:Male; D011791:Quartz / Q000009:adverse effects; D051381:Rats; D012829:Silicosis / Q000209:etiology* / Q000276:immunology
D000975:Antioxidants; D011791:Quartz
Vliianie antioksidantnogo statusa organizma na individual'nuiu predraspolozhennost' k silikozu (éksperimental'noe issledovanie).