title: Intravenous immunoglobulin treatment of pregnant patients with unexplained recurrent abortions.
abstract: Intravenous immunoglobulins, first given to recurrent aborters with anti-phospholipid syndrome, have been administered to unexplained aborters since 1986. They probably have immunomodulatory properties beyond supplying blocking antibodies. When pregnancy was confirmed, women were started with a loading dose which was repeated every 3-4 weeks until the second trimester. Dosages were empirical. Pregnancy rates ranged between 50 and 82%. The main maternal complications, i.e. allergic reactions and infections, were rare.
authors.affiliation: Department of Obstetrics and Gynecology, Assaf Harofe Medical Center, Zerifin, Sackler School of Medicine, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Raziel
authors.forename: A
authors.initials: A
authors.lastname: Herman
authors.forename: I
authors.initials: I
authors.lastname: Bukovsky
authors.forename: E
authors.initials: E
authors.lastname: Caspi
authors.forename: R
authors.initials: R
authors.lastname: Ron-el
mesh_terms: D000026:Abortion, Habitual / Q000276:immunology / Q000628:therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage* / Q000009:adverse effects; D011247:Pregnancy
chemical_list: D016756:Immunoglobulins, Intravenous