title: [Wobenzyme and diuretic therapy in lymphedema after breast operation].
abstract: The authors of this clinical study report the results of a controlled clinical trial in randomized parallel groups (Wobenzym vs. diuretics) of 55 female patients suffering from brachial arm lymph edema subsequent to ablatio mammae. All patients received manual and machine lymph drainage as well as gymnastics as concomitant therapy. After 7 weeks of therapy the results of the volometric assessments of the arm, the circumference of the arm and the skinfold thickness showed significant improvements compared to diuretics. In addition, the patients receiving Wobenzym reported a significantly higher proportion of patients free of pain compared to the diuretics patients. Overall safety assessment results are satisfactory thus resulting in a superior benefit/risk relation of the Wobenzym group.
authors.affiliation: Universitätsklinik für Physikalische Medizin und Rehabilitation, Wien.
authors.forename: M I
authors.initials: MI
authors.lastname: Korpan
authors.forename: V
authors.initials: V
authors.lastname: Fialka
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage* / Q000009:adverse effects; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004232:Diuretics / Q000008:administration & dosage* / Q000009:adverse effects; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006867:Hydrolases / Q000008:administration & dosage* / Q000009:adverse effects; D008197:Lymph Node Excision; D008209:Lymphedema / Q000188:drug therapy* / Q000209:etiology; D008408:Mastectomy; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology; D012431:Rutin / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D000276:Adjuvants, Immunologic; D004232:Diuretics; D004338:Drug Combinations; D012431:Rutin; C023295:Wobenzym; D006867:Hydrolases
vernacular_title: Wobenzym- und Diuretikatherapie beim Lymphödem nach Mammaoperation.