title: Description of new composite tissue transfer for salvage of a complex hand defect.
abstract: Leiomyosarcoma of the soft tissue involving bones is an extremely rare tumor. In the past, a hand tumor of this type required amputation. Presently, with improved chemotherapy and reconstruction, the hand and its dexterity sometimes can be saved. In this case, after chemotherapy, the authors opted for wide excision including the skin, tendons, muscles, and bones. The large defect was reconstructed with an iliac crest autograft and a dorsalis pedis free flap including tendons. Functional result was excellent in this patient. The pathologic results also were reviewed by histology, immunohistochemistry for muscle marker, and electron microscopy.
authors.affiliation: Department of Orthopedic Surgery, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Osaka
authors.forename: M
authors.initials: M
authors.lastname: Hoshi
authors.forename: S
authors.initials: S
authors.lastname: Sano
authors.forename: M
authors.initials: M
authors.lastname: Nozaki
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation; D006801:Humans; D007890:Leiomyosarcoma / Q000601:surgery*; D008297:Male; D008663:Metacarpus; D012983:Soft Tissue Neoplasms / Q000601:surgery*; D013524:Surgical Flaps; D016896:Treatment Outcome