title: Non-union of mandibulotomy sites following irradiation for squamous cell carcinoma of the oral cavity.
abstract: Mandibulotomy improves surgical access to the oral cavity for the resection of tumours. Non-union of the mandibulotomy due to osteoradionecrosis has been observed in five patients with oral squamous cell carcinoma, all of whom had radiotherapy either as the primary modality of treatment or for tumour recurrence. This paper reports this series of patients, discusses their management and highlights the risk factors for the development of osteoradionecrosis.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Ashford Hospital, Middlesex.
authors.forename: K
authors.initials: K
authors.lastname: Altman
authors.forename: B M
authors.initials: BM
authors.lastname: Bailey
mesh_terms: D001860:Bone Plates; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000601:surgery; D017577:Cutaneous Fistula / Q000209:etiology; D006801:Humans; D008334:Mandible / Q000601:surgery*; D008336:Mandibular Diseases / Q000150:complications* / Q000209:etiology; D009059:Mouth Diseases / Q000209:etiology; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000601:surgery; D010025:Osteoradionecrosis / Q000150:complications* / Q000209:etiology; D010027:Osteotomy; D011183:Postoperative Complications; D011878:Radiotherapy / Q000009:adverse effects*; D012307:Risk Factors; D017211:Treatment Failure; D014945:Wound Healing / Q000528:radiation effects