title: Plasmacytoma-associated neuronal glycoprotein, Pang, maps to mouse chromosome 6 and human chromosome 3.
abstract: A new member of the immunoglobulin/fibronectin superfamily of adhesion molecules, Pang (plasmacytoma-associated neuronal glycoprotein), was recently isolated from a plasmacytoma. In previous studies, Pang was found to be normally expressed in the brain and ectopically activated by intracisternal A-type particle long terminal repeats in plasmacytomas. In this study, Pang was initially mapped to mouse Chr 6 by somatic cell hybrid analysis and further positioned on the chromosome between Wnt7a and Pcp1. Southern blot analysis of human-rodent somatic cell hybrids together with predictions from the mouse map location indicate that human PANG is located at 3p26.
authors.affiliation: Laboratory of Genetics, NIH, Bethesda, Maryland, 20892-4255, USA.
authors.forename: B A
authors.initials: BA
authors.lastname: Mock
authors.forename: M A
authors.initials: MA
authors.lastname: Connelly
authors.forename: O W
authors.initials: OW
authors.lastname: McBride
authors.forename: C A
authors.initials: CA
authors.lastname: Kozak
authors.forename: K B
authors.initials: KB
authors.lastname: Marcu
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D015816:Cell Adhesion Molecules, Neuronal / Q000096:biosynthesis / Q000235:genetics*; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D058966:Contactins; D006224:Cricetinae; D003412:Cricetulus; D003433:Crosses, Genetic; D007426:Genes, Intracisternal A-Particle; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D009115:Muridae; D009363:Neoplasm Proteins / Q000235:genetics; D010954:Plasmacytoma / Q000235:genetics / Q000378:metabolism; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping
chemical_list: C484185:CNTN3 protein, human; D015816:Cell Adhesion Molecules, Neuronal; C085907:Cntn3 protein, mouse; D058966:Contactins; D005819:Genetic Markers; D009363:Neoplasm Proteins