Community-acquired toxigenic Clostridium difficile diarrhoea in the normoxaemic elderly who have received no antimicrobials: soft evidence for ischaemic colitis?
We report three examples of community-acquired toxigenic Clostridium difficile diarrhoea in elderly patients who had neither received antimicrobial therapy nor been institutionalised. These cases stimulated interest in the non-antimicrobial changes which might predispose the host to C. difficile-related disease and raised the spectre of bowel ischaemia as a possible aetiological factor.
Laing
R B
RB
Infection Unit, Aberdeen Royal Infirmary, Foresterhill.
Dykhuizen
R S
RS
Smith
C C
CC
Gould
I W
IW
Reid
T M
TM
D000368:Aged; D000369:Aged, 80 and over; D016360:Clostridioides difficile; D017091:Colitis, Ischemic / Q000150:complications*; D003967:Diarrhea / Q000209:etiology; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology*; D005260:Female; D006801:Humans; D010100:Oxygen / Q000097:blood
D010100:Oxygen