title: Inhibitory effects of some steroidal saponins on human spermatozoa in vitro.
abstract: Twenty-nine C-27 steroidal saponins were tested for the inhibitory effects on human spermatozoa in vitro by means of a modified Sander-Cramer method. Twelve of them are responsible for this activity. The structure-activity relationship is discussed.
authors.affiliation: Laboratory of Phytochemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Yunnan, China.
authors.forename: Y F
authors.initials: YF
authors.lastname: Wang
authors.forename: X C
authors.initials: XC
authors.lastname: Li
authors.forename: H Y
authors.initials: HY
authors.lastname: Yang
authors.forename: J J
authors.initials: JJ
authors.lastname: Wang
authors.forename: C R
authors.initials: CR
authors.lastname: Yang
mesh_terms: D006801:Humans; D008297:Male; D010944:Plants; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects* / Q000502:physiology; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D012503:Saponins; D013256:Steroids