5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors.
Rowley
M
M
Merck Sharp and Dohme, Neuroscience Research Centre, Harlow, Essex, U.K.
Broughton
H B
HB
Collins
I
I
Baker
R
R
Emms
F
F
Marwood
R
R
Patel
S
S
Patel
S
S
Ragan
C I
CI
Freedman
S B
SB
Leeson
P D
PD
D003001:Cloning, Molecular; D018492:Dopamine Antagonists / Q000737:chemistry / Q000494:pharmacology*; D065127:Dopamine D2 Receptor Antagonists; D006801:Humans; D007555:Isoxazoles / Q000737:chemistry / Q000494:pharmacology*; D010880:Piperidines / Q000737:chemistry / Q000494:pharmacology*; D017448:Receptors, Dopamine D2 / Q000235:genetics; D050638:Receptors, Dopamine D4
C493599:DRD4 protein, human; D018492:Dopamine Antagonists; D065127:Dopamine D2 Receptor Antagonists; D007555:Isoxazoles; D010880:Piperidines; D017448:Receptors, Dopamine D2; D050638:Receptors, Dopamine D4; C099631:L 741742