title: Antibodies to four gram-negative bacteria in rheumatoid arthritis which share sequences with the rheumatoid arthritis susceptibility motif.
abstract: The bacteria Proteus, Serratia, Escherichia and Pseudomonas possess sequences resembling the rheumatoid arthritis susceptibility sequence EQRRAA, but antibodies were elevated only to Proteus in 66 RA patients (P<0.001) when compared to 61 active ankylosing spondylitis patients and 60 controls.
authors.affiliation: Division of Life Sciences, King's College, London.
authors.forename: H
authors.initials: H
authors.lastname: Tiwana
authors.forename: C
authors.initials: C
authors.lastname: Wilson
authors.forename: P
authors.initials: P
authors.lastname: Cunningham
authors.forename: A
authors.initials: A
authors.lastname: Binder
authors.forename: A
authors.initials: A
authors.lastname: Ebringer
mesh_terms: D000328:Adult; D000368:Aged; D000595:Amino Acid Sequence; D000907:Antibodies, Bacterial / Q000097:blood*; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D004198:Disease Susceptibility; D004797:Enzyme-Linked Immunosorbent Assay; D004926:Escherichia coli / Q000276:immunology; D005260:Female; D006092:Gram-Negative Facultatively Anaerobic Rods / Q000235:genetics / Q000276:immunology*; D006684:HLA-DR Antigens; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D011511:Proteus / Q000276:immunology; D011513:Proteus mirabilis / Q000276:immunology; D017386:Sequence Homology, Amino Acid; D012706:Serratia marcescens / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D006684:HLA-DR Antigens; D007136:Immunoglobulins