title: [Therapeutic strategy in breast cancer].
abstract: The authors present the actual concepts of the therapeutic strategy for the breast cancer. The choice of the optimal protocol treatment is based on a complete and correct pretherapeutic evaluation. This implies the staging using TNM/ UICC/ 1987 system (explained in the text) and the definition of the prognostic factors: axillary lymph node involvement, other pathological patterns, the situation of the hormonal receptors and the cell proliferation index. For the stages I-II the strategy of the treatment include: modified radical mastectomy, postoperative irradiation in well defined cases and the adjuvant systemic treatment using chemotherapy and hormonal therapy. The laparoscopic ovariectomy is a safe and simple technique. For the local advanced cancer (IIIA and IIIB) the treatment begins with a systemic aggressive approach, the surgery being applied following the tumoral regression. In the stage IV the complex palliative treatment is indicated.
authors.affiliation: Clinica de Oncologie--Radioterapie, Spital Clinic Coltea.
authors.forename: I
authors.initials: I
authors.lastname: Florea
authors.forename: C
authors.initials: C
authors.lastname: Dragomirescu
authors.forename: C
authors.initials: C
authors.lastname: Aldea
authors.forename: C
authors.initials: C
authors.lastname: Mihai
authors.forename: B
authors.initials: B
authors.lastname: Lişcu
authors.forename: M
authors.initials: M
authors.lastname: Liţescu
authors.forename: V
authors.initials: V
authors.lastname: Pento
authors.forename: R
authors.initials: R
authors.lastname: Vizeteu
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D009367:Neoplasm Staging; D011379:Prognosis
vernacular_title: Strategia terapeutică în cancerul mamar.