Correlation of hydrogen and methane production to rice carbohydrate malabsorption in Burmese (Myanmar) children.
Rice carbohydrate malabsorption is common in Burmese village children and adults and may contribute to diminished growth. Its diagnosis depends on a rice breath hydrogen test, which has limitations. Almost 20% of Burmese children under age 5 produce methane, compared with less than 7% of children in Africa and Hong Kong. If an increased carbohydrate load in the colon due to rice malabsorption provides increased substrate for methanogenic bacteria in the left colon, higher fasting breath methane concentrations might be a simpler method of diagnosing rice malabsorption. We tested breath hydrogen and methane over a 4-h period and did anthropometric measurements in 142 subjects, 79 children, and 63 adults. Seventy percent of children were rice-malabsorbers. Methane production occurred in 20% of children under 5 years of age and increased to 60% of adults. There is an association of rice malabsorption with reduced length. There was not correlation between rice malabsorption and breath methane, and the concentration of breath methane does not, therefore, indicate rice absorption status and cannot replace rice breath hydrogen tests.
Bolin
T D
TD
Gastrointestinal Unit, Prince of Wales Hospital, Randwick NSW, Australia.
Myo-Khin
Soe-Aung
Genge
J R
JR
Duncombe
V M
VM
D000328:Adult; D000375:Aging / Q000378:metabolism / Q000502:physiology; D000886:Anthropometry; D001827:Body Height; D001944:Breath Tests; D002648:Child; D002675:Child, Preschool; D003106:Colon / Q000378:metabolism / Q000382:microbiology; D004040:Dietary Carbohydrates / Q000032:analysis / Q000378:metabolism / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D006859:Hydrogen / Q000378:metabolism*; D007223:Infant; D008286:Malabsorption Syndromes / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism*; D008297:Male; D008697:Methane / Q000378:metabolism*; D008875:Middle Aged; D002052:Myanmar / Q000453:epidemiology; D009752:Nutritional Status; D012275:Oryza / Q000737:chemistry / Q000378:metabolism*; D015995:Prevalence
D004040:Dietary Carbohydrates; D006859:Hydrogen; D008697:Methane