Invasive malignant fibrous histiocytoma in a cow.
An invasive malignant fibrous histiocytoma associated with the left cornual process, and causing lysis of the frontal bone, was diagnosed in a cow. The mass compressed the left cerebral hemisphere focally and extended into the frontal sinus and ethmoid and nasal turbinates. It was composed of pleomorphic to spindle-shaped cells with ultra-structural evidence of fibroblastic, myofibroblastic, and fibrohistiocytic differentiation. Trauma and chronic inflammation may be predisposing factors for development of neoplasia in cattle.
Sartin
E A
EA
Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849-5519, USA.
Hudson
J A
JA
Herrera
G A
GA
Dickson
A M
AM
Wolfe
D F
DF
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D006733:Horns / Q000293:injuries / Q000601:surgery; D009361:Neoplasm Invasiveness; D009369:Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*