title: [Evaluation of the efficacy of levamisole in corticosteroid-dependent nephrotic syndrome in children].
abstract: The efficacy of levamisole was evaluated in 22 steroid-dependent nephrotic children. All of them were treated before with glucocorticoids. In 45.5% of children, prednisone was with-drawn after levamisole treatment and the remissions obtained lasted more than six months, 18.2% of the children relapsed after prednisone withdrawal and 36.4% children did not respond to levamisole treatment. Levamisole could be recommended for steroid-dependent patients with recurrent infections, in which alkylating agents are contraindicated.
authors.affiliation: Oddział Nefrologii, Dializoterapii i Transplantacji Nerek CZD w Warszawie.
authors.forename: J
authors.initials: J
authors.lastname: Ksiazek
authors.forename: J
authors.initials: J
authors.lastname: Kryński
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005938:Glucocorticoids / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D011241:Prednisone / Q000494:pharmacology / Q000627:therapeutic use*; D012008:Recurrence; D012074:Remission Induction; D019966:Substance-Related Disorders
chemical_list: D000276:Adjuvants, Immunologic; D005938:Glucocorticoids; D007978:Levamisole; D011241:Prednisone
vernacular_title: Ocena skuteczności lewamizolu u dzieci ze sterydozaleznym zespołem nerczycowym.