A pilot study of outpatient management of febrile neutropenic children with cancer at low risk of bacteremia.
Febrile neutropenic children with cancer were eligible for outpatient management with intravenous ceftriaxone therapy if they displayed selected low-risk criteria. Nineteen children were enrolled. All patients had sterile blood cultures, and only one of them was hospitalized because of persistent fever. This pilot study suggests that selected children with febrile neutropenia might be successfully managed without hospitalization.
Mustafa
M M
MM
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9063, USA.
Aquino
V M
VM
Pappo
A
A
Tkaczewski
I
I
Buchanan
G R
GR
D000293:Adolescent; D000553:Ambulatory Care; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy* / Q000209:etiology; D002443:Ceftriaxone / Q000009:adverse effects / Q000627:therapeutic use*; D002511:Cephalosporins / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005335:Fever of Unknown Origin / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D009369:Neoplasms / Q000188:drug therapy*; D009503:Neutropenia / Q000139:chemically induced* / Q000188:drug therapy; D009504:Neutrophils / Q000187:drug effects; D010976:Platelet Count / Q000187:drug effects; D016896:Treatment Outcome
D002511:Cephalosporins; D002443:Ceftriaxone