title: The fronto-temporal component in mild and moderately severe head injury.
abstract: The history of the identification of the so-called (fronto-)temporal lobe contusion is reviewed. Treatment of minor head injuries actually starts with the right diagnosis. Injuries of the temporal lobe, characterized by a comparatively long period of post-traumatic amnesia should be distinguished from minor head injuries (cerebral concussion). Treatment of minor head injuries should include good information and explanation of the medical aspects of minor head injuries to prevent the so called post-concussional syndrome, with long lasting sequelae. Changes of neurotransmitter metabolism in various kinds of head injuries have been known for many years. Treatment with precursors of neurotransmitters (particularly physostigmine and L-DOPA) can be useful in unconsciousness and amnestic syndromes.
authors.affiliation: Department of Neurology, University Hospital, Groningen.
authors.forename: J M
authors.initials: JM
authors.lastname: Minderhoud
authors.forename: A H
authors.initials: AH
authors.lastname: van Zomeren
authors.forename: J
authors.initials: J
authors.lastname: van der Naalt
mesh_terms: D001924:Brain Concussion / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D003288:Contusions / Q000188:drug therapy / Q000503:physiopathology; D006259:Craniocerebral Trauma / Q000378:metabolism / Q000503:physiopathology*; D004569:Electroencephalography; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000378:metabolism; D013702:Temporal Lobe / Q000503:physiopathology*
chemical_list: D018377:Neurotransmitter Agents