Comparative performance for immediate hypersensitivity skin testing using two skin prick test devices.
Fifty-five patients were skin-tested by Multi-Test (M) and needle prick test (NPT) to compare the reproducibility of the methods. We used 6 allergenic extracts: Dermatophagoides pteronyssinus, Dermatophagoides farinae, dog epithelium, cat pelt, American cockroach and mixed molds. A glycerosaline and a positive control (histamine 1 mg/ml) were performed in both methods. Statistically significant differences in histamine and Dermatophagoides farinae wheal reactions between the two methods (M > NPT) were found, with no differences with the other allergenic extracts. We concluded that the two methods are similar with respect to determining the immediate hypersensitivity, but the Multi-Test is better accepted by children.
Rizzo
M C
MC
Division of Allergy, Clinical Immunology and Rheumatology, Federal University of São Paulo, Brazil.
Naspitz
C K
CK
Solé
D
D
D000293:Adolescent; D000485:Allergens / Q000276:immunology; D001249:Asthma / Q000175:diagnosis; D002648:Child; D005260:Female; D006632:Histamine / Q000276:immunology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis*; D008297:Male; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis; D012882:Skin Tests / Q000379:methods*
D000485:Allergens; D006632:Histamine