title: Incidence of anti-Toxoplasma antibodies in women with high-risk pregnancy and habitual abortions.
abstract: Toxoplasmosis is a zoonosis caused by Toxoplasma gondii, an obligate intracellular parasite. In pregnant women on the worldwide scale, there are seroprevalences from 7% to 51.3% and in women with abnormal pregnancies and abortions the seroprevalences vary from 17.5% to 52.3%. In Mexico, seropositivity has been found to vary from 18.2% to 44.8% in women with abnormal deliveries or abortions. This study's aim was to determine the incidence of IgG and IgM anti-Toxoplasma antibodies in women at the Gineco-Obstetrics Hospital of the Western Medical Center of the Mexican Social Security Institute. Three hundred and fifty women with high-risk pregnancies were studied, and 122 (34.9%) were found to be IgG seropositive and 76 (20.7%) were IgM positive. In one group of women with habitual abortions there were 48 (44.9%) with the presence of IgG antibodies and 33 (33.3%) were IgM seropositive. Seropositivity was analyzed according to age, occupation, socio-economic level, eating raw or poorly cooked meat, and living with cats.
authors.affiliation: Centro de Docencia, Investigación y Diagnóstico de Enfermedades Tropicales, Universidad de Guadalajara, Mexico.
authors.forename: M L
authors.initials: ML
authors.lastname: Galván Ramírez
authors.forename: J L
authors.initials: JL
authors.lastname: Soto Mancilla
authors.forename: O
authors.initials: O
authors.lastname: Velasco Castrejón
authors.forename: R
authors.initials: R
authors.lastname: Pérez Medina
mesh_terms: D000026:Abortion, Habitual / Q000453:epidemiology* / Q000276:immunology; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D002415:Cats; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D015994:Incidence; D008800:Mexico / Q000453:epidemiology; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000453:epidemiology* / Q000276:immunology; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology* / Q000276:immunology; D015047:Zoonoses
chemical_list: D000913:Antibodies, Protozoan