title: Management of asymptomatic mild aortic stenosis during coronary artery operations.
abstract: BACKGROUND
  Management of asymptomatic mild aortic stenosis at the time of coronary artery bypass grafting (CABG) remains controversial. We have retrospectively analyzed a cohort of patients requiring aortic valve replacement (AVR) subsequent to CABG and compared their operative morbidity and mortality with that of a group receiving CABG and AVR simultaneously at the first operation.
  
  
  METHODS
  Analysis is drawn from 28 patients who required AVR 8 +/- 4 years subsequent to CABG (group A) and 175 patients receiving AVR along with CABG at the primary operation (group B). Groups were similar with respect to age, sex, risk factors for cardiac disease, extent of coronary artery disease, left ventricular function, New York Heart Association class, aortic valve area, number of grafts, and size of prosthesis inserted.
  
  
  RESULTS
  Patients having AVR subsequent to CABG had a significantly prolonged aortic cross-clamp time and global myocardial ischemic time and incurred a twofold increase in operative mortality. The actuarial survival at 10 years was not significantly different between cohorts. In the 28 patients in group A, the aortic valve area during the period between operations decreased 0.05 mm2/y.
  
  
  CONCLUSIONS
  The operative mortality and morbidity of a second operation for AVR is high, but there is no significant difference in survival at 10 years. In at least a portion of patients having mild aortic stenosis at the time of CABG there will be progression of the stenosis necessitating reoperation at a later date.
authors.affiliation: Division of Cardiothoracic Surgery, St. Louis University Health Sciences Center, Missouri, USA.
authors.forename: A C
authors.initials: AC
authors.lastname: Fiore
authors.forename: M T
authors.initials: MT
authors.lastname: Swartz
authors.forename: K S
authors.initials: KS
authors.lastname: Naunheim
authors.forename: D A
authors.initials: DA
authors.lastname: Moroney
authors.forename: D A
authors.initials: DA
authors.lastname: Canvasser
authors.forename: L R
authors.initials: LR
authors.lastname: McBride
authors.forename: P S
authors.initials: PS
authors.lastname: Peigh
authors.forename: G C
authors.initials: GC
authors.lastname: Kaiser
authors.forename: V L
authors.initials: VL
authors.lastname: Willman
mesh_terms: D000206:Actuarial Analysis; D000368:Aged; D001021:Aortic Valve / Q000473:pathology / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000473:pathology / Q000601:surgery*; D002315:Cardiopulmonary Bypass; D015331:Cohort Studies; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods; D003327:Coronary Disease / Q000473:pathology / Q000601:surgery; D018450:Disease Progression; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000503:physiopathology; D011183:Postoperative Complications; D011474:Prosthesis Design; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D013997:Time Factors; D016277:Ventricular Function, Left