[Hypercalcemia a sign of medullar transformation of low grade malignant lymphoma. Apropos of a case].
The authors report a case of transformation of a low grade non-Hodgkin's lymphoma (LGL) to an agressive lymphoma in a 55 year-old woman who was treated by fludarabine phosphate. The only sign of transformation was the supervention of an hypercalcemia. This complication is rare in the evolution of the LGL and the mechanism is original.
Joly
F
F
Service d'hématologie clinique, CHU, Caen, France.
Reman
O
O
Penther
D
D
Levaltier
X
X
Troussard
X
X
Leporrier
M
M
D001859:Bone Neoplasms / Q000175:diagnosis; D002117:Calcitriol / Q000097:blood; D002118:Calcium / Q000652:urine; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology* / Q000503:physiopathology; D008228:Lymphoma, Non-Hodgkin / Q000097:blood / Q000150:complications* / Q000652:urine; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood*
D010281:Parathyroid Hormone; D002117:Calcitriol; D002118:Calcium
Hypercalcémie: signe de transformation médullaire d'un lymphome de faible grade de malignité. A propos d'une observation.