Antibody-directed enzyme prodrug therapy (ADEPT) for treatment of major solid tumour disease.
Blakey
D C
DC
Cancer Research Department, Zeneca Pharmaceuticals, Macclesfield, Cheshire, U.K.
Burke
P J
PJ
Davies
D H
DH
Dowell
R I
RI
Melton
R G
RG
Springer
C J
CJ
Wright
A F
AF
D000818:Animals; D057487:Enzyme Therapy; D004798:Enzymes / Q000008:administration & dosage; D006801:Humans; D018796:Immunoconjugates / Q000008:administration & dosage / Q000627:therapeutic use*; D009150:Mustard Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000628:therapy*; D011355:Prodrugs / Q000008:administration & dosage / Q000627:therapeutic use*; D014183:Transplantation, Heterologous
D004798:Enzymes; D018796:Immunoconjugates; D009150:Mustard Compounds; D011355:Prodrugs