title: Within-centre evaluation of hypercalcaemia discriminant functions 5 years after their development.
abstract: Diagnostic hypercalcaemia discriminant functions, discriminating between clinically significant and non-significant hypercalcaemia, were tested 5 years after their development in order to evaluate the impact of time on their diagnostic capacity. Two populations, consisting of 257 and 129 patients with hypercalcaemia, were consecutively recorded, during six and three months respectively, 5 years apart under similar circumstances. The prevalence of hypercalcaemia was comparable in both populations, being 2.57 and 2.38% respectively (non-significant) (NS). The female/male ratio was 1.9 and 1.7 (NS). The discriminant functions correctly classified 81 and 80% of the women, respectively (NS) and respectively 75% and 64% of the men (NS) in the first and second recorded populations.
authors.affiliation: Department of Clinical Chemistry, Hvidovre Hospital, Copenhagen, Denmark.
authors.forename: A
authors.initials: A
authors.lastname: Frølich
authors.forename: B F
authors.initials: BF
authors.lastname: Nielsen
authors.forename: K
authors.initials: K
authors.lastname: Conradsen
authors.forename: P
authors.initials: P
authors.lastname: McNair
authors.forename: I B
authors.initials: IB
authors.lastname: Transbøl
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D003404:Creatinine / Q000097:blood; D003661:Decision Support Techniques; D016002:Discriminant Analysis; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology*; D006961:Hyperparathyroidism / Q000097:blood / Q000175:diagnosis*; D008297:Male; D009369:Neoplasms / Q000097:blood / Q000175:diagnosis*; D012680:Sensitivity and Specificity
chemical_list: D003404:Creatinine; D000469:Alkaline Phosphatase