On the structure of replication and transcription factories.
Recent experiments suggest that active polymerases are concentrated in large structures, 'factories', within eukaryotic nuclei. Data concerning the structure of these factories is reviewed.
Hughes
T A
TA
CRC Nuclear Structure and Function Research Group, Sir William Dunn School of Pathology, University of Oxford, UK.
Pombo
A
A
McManus
J
J
Hozák
P
P
Jackson
D A
DA
Cook
P R
PR
D000818:Animals; D002467:Cell Nucleus / Q000201:enzymology / Q000648:ultrastructure*; D004261:DNA Replication; D004259:DNA-Directed DNA Polymerase / Q000032:analysis; D012321:DNA-Directed RNA Polymerases / Q000032:analysis; D006801:Humans; D008957:Models, Genetic; D014158:Transcription, Genetic
D012321:DNA-Directed RNA Polymerases; D004259:DNA-Directed DNA Polymerase