[Digitalis in atrial fibrillation. Still relevant treatment or an old-fashioned therapy?].
The scientific validation of digitalis as the routine treatment for atrial fibrillation is far from satisfactory. Whereas digitalis reduces the ventricular rate at rest, patients may still experience a too rapid heart rate during exercise unless additional drugs are given to reduce atrio-ventricular conduction. Digitalis is often prescribed in paroxysmal atrial fibrillation despite lack of documentation of benefit from this treatment. Finally, digitalis may cause proarrhytmias, and a prothrombotic drug effect cannot be excluded.
Gjesdal
K
K
Medisinsk klinikk, Ullevål sykehus, Oslo.
D001281:Atrial Fibrillation / Q000188:drug therapy* / Q000503:physiopathology; D002316:Cardiotonic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004071:Digitalis Glycosides / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans
D002316:Cardiotonic Agents; D004071:Digitalis Glycosides
Digitalis ved atrieflimmer. Fortsatt en god behandling eller foreldet terapi?