A 500-kb physical map and contig from the Harvey ras-1 gene to the 11p telomere.
A contiguous physical map was constructed from the Harvey ras-1 (HRAS1) gene to the 11p telomere. The contig spans approximately 500 kb and is minimally composed of a telomere-containing YAC and P1 and cosmid clones. Included in the contig are 11 sequence-tagged sites derived from P1 and cosmid ends. Three genes were placed on the contig in the following order: telomere-ribonuclease/angiogenin inhibitor (RNH)-Harvey ras-1 (HRAS1)-HRAS1-related complex (HRC). Two novel tetranucleotide repeats (heterozygosity of 66 and 68%) and a complex CA repeat (heterozygosity of 78%) were isolated and characterized.
Russell
M W
MW
Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, 48109, USA.
Munroe
D J
DJ
Bric
E
E
Housman
D E
DE
Dietz-Band
J
J
Riethman
H C
HC
Collins
F S
FS
Brody
L C
LC
D001483:Base Sequence; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D002880:Chromosomes, Human, Pair 11; D018900:Dinucleotide Repeats; D011905:Genes, ras; D006580:Genetic Carrier Screening; D005819:Genetic Markers; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D019105:Random Amplified Polymorphic DNA Technique; D016615:Telomere
D005819:Genetic Markers