title: [Functional adrenal hyperandrogenism: changing perspectives during its historical evolution].
abstract: The approach to adrenal hyperandrogenism, due to genetical or non-genetical enzymatic alterations, has changed dramatically during the last 50 years. To allow a better understanding of the subject, we focused it from a historical perspective, defining four stages analyzed in detail. Now there is consent on the existence of a functional adrenal hyperandrogenism, which has an important role in acne, hirsutism and menstrual disturbances.
authors.affiliation: Departamento de Endocrinología, Hospital San Borja-Arriarán, Santiago de Chile.
authors.forename: E
authors.initials: E
authors.lastname: Devoto
authors.forename: L
authors.initials: L
authors.lastname: Aravena
mesh_terms: D000152:Acne Vulgaris / Q000209:etiology; D000311:Adrenal Glands / Q000378:metabolism; D000728:Androgens / Q000097:blood / Q000378:metabolism*; D005260:Female; D006628:Hirsutism / Q000209:etiology; D049673:History, 20th Century; D006801:Humans; D017588:Hyperandrogenism / Q000266:history*; D008599:Menstruation Disturbances / Q000209:etiology; D010053:Ovary / Q000378:metabolism
chemical_list: D000728:Androgens
vernacular_title: Hiperandrogenismo suprarrenal funcional: perspectivas cambiantes en su evolución histórica.