[Functional adrenal hyperandrogenism: changing perspectives during its historical evolution].
The approach to adrenal hyperandrogenism, due to genetical or non-genetical enzymatic alterations, has changed dramatically during the last 50 years. To allow a better understanding of the subject, we focused it from a historical perspective, defining four stages analyzed in detail. Now there is consent on the existence of a functional adrenal hyperandrogenism, which has an important role in acne, hirsutism and menstrual disturbances.
Devoto
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Departamento de Endocrinología, Hospital San Borja-Arriarán, Santiago de Chile.
Aravena
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L
D000152:Acne Vulgaris / Q000209:etiology; D000311:Adrenal Glands / Q000378:metabolism; D000728:Androgens / Q000097:blood / Q000378:metabolism*; D005260:Female; D006628:Hirsutism / Q000209:etiology; D049673:History, 20th Century; D006801:Humans; D017588:Hyperandrogenism / Q000266:history*; D008599:Menstruation Disturbances / Q000209:etiology; D010053:Ovary / Q000378:metabolism
D000728:Androgens
Hiperandrogenismo suprarrenal funcional: perspectivas cambiantes en su evolución histórica.