title: Suspected idiopathic CD4+ T-lymphocytopenia in a young patient with vulvar carcinoma stage IV.
abstract: A case of a woman having a large invasive vulvar carcinoma is reported. Because of the early age of onset and recurrent pneumonia, immunodeficiency was suspected. There appeared to be a repetitive low CD4+ T-lymphocyte count, without evidence of HIV infection or other diseases or therapies known to be clearly associated with T-cell depletion. This is suspected for the rare disorder known as idiopathic CD4+ T-lymphocytopenia which is often associated with opportunistic infections. A case of suspected idiopathic CD4+ T-lymphocytopenia in a patient having an invasive vulvar carcinoma is described.
authors.affiliation: Department of Gynecology, University Hospital Rotterdam Dijkzigt, The Netherlands.
authors.forename: R J
authors.initials: RJ
authors.lastname: Rijnders
authors.forename: I E
authors.initials: IE
authors.lastname: van den Ende
authors.forename: F J
authors.initials: FJ
authors.lastname: Huikeshoven
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000150:complications* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000150:complications* / Q000175:diagnosis*; D014846:Vulvar Neoplasms / Q000150:complications* / Q000473:pathology