title: Glycans of bovine lactoferrin function as receptors for the type 1 fimbrial lectin of Escherichia coli.
abstract: Bovine lactoferrin strongly inhibited the hemagglutination activity of type 1 fimbriated Escherichia coli. In addition, it agglutinated these bacteria. The agglutination reaction was specifically inhibited by glycopeptides derived from bovine lactoferrin or alpha-methyl-D-mannoside. These observations indicate that the glycans of bovine lactoferrin can serve as receptors for type 1 fimbrial lectin.
authors.affiliation: Nutritional Science Laboratory, Morinaga Milk Industry Co., Ltd., Zama City, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Teraguchi
authors.forename: K
authors.initials: K
authors.lastname: Shin
authors.forename: Y
authors.initials: Y
authors.lastname: Fukuwatari
authors.forename: S
authors.initials: S
authors.lastname: Shimamura
mesh_terms: D000371:Agglutination; D000818:Animals; D002417:Cattle; D004926:Escherichia coli / Q000378:metabolism*; D006168:Guinea Pigs; D006384:Hemagglutination; D007781:Lactoferrin / Q000378:metabolism*; D037102:Lectins / Q000378:metabolism*; D011134:Polysaccharides / Q000378:metabolism*; D011971:Receptors, Immunologic / Q000378:metabolism*
chemical_list: D037102:Lectins; D011134:Polysaccharides; D011971:Receptors, Immunologic; C037872:pili, bacterial receptor; D007781:Lactoferrin