title: The lunula.
abstract: The lunula is the visible portion of the distal nail matrix that extends beyond the proximal nailfold. It is white, half-moon-shaped, appears by week 14 of gestation, has unique histologic features. The lunula has a primary structural role in defining the free edge of the distal nail plate. Lunular anomalies include changes in form and structure and in color. Lunular dysmorphologic features can be characterized by macrolunula, microlunula or anolunula, and nonconvex lunula. Lunular dyschromias can be confluent or spotted or can be characterized by longitudinal colored bands that traverse the lunula. Alterations in the morphologic features or color (or both) of the lunula can be an indication of either a cutaneous or a systemic disorder.
authors.affiliation: Department of Dermatology, University of Texas-Houston Medical School 77030, USA.
authors.forename: P R
authors.initials: PR
authors.lastname: Cohen
mesh_terms: D003116:Color; D004194:Disease; D006801:Humans; D009260:Nail Diseases / Q000209:etiology / Q000473:pathology; D009262:Nails / Q000033:anatomy & histology* / Q000187:drug effects / Q000502:physiology; D009264:Nails, Malformed; D012871:Skin Diseases / Q000175:diagnosis