Effects of calmodulin antisense oligonucleotides on chemoresponse in Paramecium.
The calcium/calmodulin-regulated Ca-ATPase of the plasma membrane is implicated in Paramecium chemosensory transduction. Calmodulin antisense oligonucleotides electroporated into Paramecium disrupt chemosensory responses to sodium acetate but not to ammonium chloride.
Yano
J
J
University of Vermont, Department of Biology, Burlington 04505, USA.
Fraga
D
D
Hinrichsen
R
R
Van Houten
J L
JL
D000085:Acetates / Q000494:pharmacology; D019342:Acetic Acid; D000643:Ammonium Chloride / Q000494:pharmacology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D000252:Calcium-Transporting ATPases / Q000037:antagonists & inhibitors / Q000502:physiology; D002147:Calmodulin / Q000235:genetics*; D016376:Oligonucleotides, Antisense / Q000494:pharmacology*; D010247:Paramecium / Q000187:drug effects* / Q000502:physiology
D000085:Acetates; D002147:Calmodulin; D016376:Oligonucleotides, Antisense; D000643:Ammonium Chloride; D000252:Calcium-Transporting ATPases; D019342:Acetic Acid