Loss of olfactory function leads to a decrease of trigeminal sensitivity.
Healthy controls were compared to patients with decreased olfactory sensitivity (n = 32) to investigate interactions between the olfactory and trigeminal systems. Amplitudes of chemo-somatosensory event-related potentials in response to suprathreshold trigeminal stimuli (CO2) were found to be smaller in patients (P < 0.05) indicating a decrease of trigeminally mediated sensations.
Hummel
T
T
Department of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nürnberg, Germany.
Barz
S
S
Lötsch
J
J
Roscher
S
S
Kettenmann
B
B
Kobal
G
G
D000200:Action Potentials; D000328:Adult; D000368:Aged; D006801:Humans; D008875:Middle Aged; D009832:Olfactory Nerve / Q000503:physiopathology*; D012903:Smell / Q000502:physiology*; D014276:Trigeminal Nerve / Q000503:physiopathology*