title: [S and R forms of Mycobacterium tuberculosis as a problem of producing cloned and phenotypically competent strains].
abstract: The authors suggest that animals and humans carry M. tuberculosis in S form. These mycobacteria are virulent, do not form conglomerates and represent biologically most potent form. The state of R-form M. tuberculosis results from their culturing on artificial culture media which fail to secure compatible conditions for cells. M. tuberculosis S-form is convenient for microbiological and molecular-genetic research. The authors offer a method of biological production of single M. tuberculosis in S form.
authors.forename: A A
authors.initials: AA
authors.lastname: Korneev
authors.forename: V A
authors.initials: VA
authors.lastname: Puzanov
authors.forename: T D
authors.initials: TD
authors.lastname: Grishina
authors.forename: L N
authors.initials: LN
authors.lastname: Chernousova
authors.forename: O A
authors.initials: OA
authors.lastname: Kalinina
authors.forename: N V
authors.initials: NV
authors.lastname: Musabekova
mesh_terms: D003470:Culture Media; D009163:Mycobacterium bovis / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000254:growth & development* / Q000472:pathogenicity; D010641:Phenotype; D012106:Research
chemical_list: D003470:Culture Media
vernacular_title: S- i R-formy Mycobacterium tuberculosis kak problema polucheniia klonirovannykh i fenotipicheski polnotsennykh shtammov.