title: Eosinophilic panniculitis: diagnostic considerations and evaluation.
abstract: BACKGROUND
  Eosinophilic panniculitis is characterized by a prominent infiltration of subcutaneous fat with eosinophils. It has been identified in patients who have a variety of associated clinical conditions.
  
  
  OBJECTIVE
  Our purpose was to describe clinical conditions associated with eosinophilic panniculitis.
  
  
  METHODS
  We describe five patients with eosinophilic panniculitis. These patients had a variety of clinical conditions including arthropod bites, gnathostomiasis, and polyarteritis nodosa. We review the literature on patients with eosinophilic panniculitis.
  
  
  RESULTS
  Eosinophilic panniculitis most often presents as a nodule. Gnathostomiasis, leukocytoclastic vasculitis, and erythema nodosum appear to be the most common conditions associated with eosinophilic panniculitis. Other disorders include atopic and contact dermatitis, eosinophilic cellulitis, injection granuloma, arthropod bites, streptococcal and other bacterial infections, toxocariasis, B- and T-cell lymphoma, and refractory anemia with excess blasts.
  
  
  CONCLUSIONS
  Once a diagnosis of eosinophilic panniculitis has been established, appropriate evaluation for an associated clinical condition should be performed.
authors.affiliation: Department of Pathology, University of Texas-Houston Medical School 77030, USA.
authors.forename: J
authors.initials: J
authors.lastname: Adame
authors.forename: P R
authors.initials: PR
authors.lastname: Cohen
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000754:Anemia, Refractory, with Excess of Blasts / Q000150:complications; D000818:Animals; D001181:Arthropods; D001733:Bites and Stings / Q000150:complications; D002481:Cellulitis / Q000150:complications; D003876:Dermatitis, Atopic / Q000150:complications; D003877:Dermatitis, Contact / Q000150:complications; D004802:Eosinophilia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D004804:Eosinophils / Q000473:pathology; D004893:Erythema Nodosum / Q000150:complications; D005260:Female; D006039:Gnathostoma; D006801:Humans; D008223:Lymphoma / Q000150:complications; D008297:Male; D008875:Middle Aged; D015434:Panniculitis / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000150:complications; D012867:Skin / Q000473:pathology; D017205:Spirurida Infections / Q000150:complications; D013290:Streptococcal Infections; D014120:Toxocariasis / Q000150:complications; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications