Hypertrophic cardiomyopathy in old agers. Definitions and general considerations.
Hypertrophic cardiomyopathy (HCM), a primary heart disease, in most of the cases genetically transmitted, characterized by hypertrophy, often asymmetric, of the left ventricle (LV), presents certain peculiarities in old agers. The shape of the LV in old agers, is characterized by aorto-septal angulation, by the frequent presence of a septal bulge and the calcification of the posterior mitral ring which contributes to the narrowing of the LV ejection tract by the anterior displacement of the mitral valve. Thus, HCM in old agers can also have an acquired component associated with the mild changes of aging, which in certain conditions can lead to the appearance of some peculiar forms of disease.
Stănescu
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N. Gh. Lupu Institute of Internal Medicine, Bucharest, Romania.
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000503:physiopathology; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged