[Cancer metastasis].
Despite increasing insight into the biology of tumour development, the number of cancer deaths has not been subsequently reduced. This may be because approximately half of the cancers have metastasized already at the time of initial diagnosis. It seems important therefore, to learn more about the complex metastatic process. This process includes several linked sequential steps, and depends on an intimate interaction between the metastatic cells and the environment. In this review, we discuss these steps with emphasis on recent studies of the various cellular interactions that take place. Understanding these factors should result in diagnostic improvements and more effective treatment of cancer metastasis.
Berner
A
A
Seksjon for cytologi, Avdeling for patologi, Det Norske Radiumhospital, Oslo.
Bryne
M
M
Thrane
P S
PS
D015815:Cell Adhesion Molecules; D002471:Cell Transformation, Neoplastic; D016147:Genes, Tumor Suppressor; D006801:Humans; D007111:Immunity, Cellular; D009362:Neoplasm Metastasis; D009389:Neovascularization, Pathologic; D009857:Oncogenes
D015815:Cell Adhesion Molecules
Spredning av kreftsvulster.