Plasmid-mediated degradation of o-phthalate and salicylate by a Moraxella sp.
A Moraxella sp. strain VG45 capable of utilizing o-phthalate and salicylate as a sole source of carbon and energy was isolated. The degradation of o-phthalate occurs via phthalate 4,5-dioxygenase, 4,5-dihydro-4,5-dihydroxyphthalate dehydrogenase, 4,5-dihydroxyphthalate decarboxylase and protocatechuate 4,5-dioxygenase. Salicylate is degraded via salicylate 5-hydroxylase, gentisate 1,2-dioxygenase and then by a glutathione-independent maleylpyruvate hydrolase. Further, a plasmid of app. 60 kilobase pairs (kb) is involved in the degradation of the o-phthalate and salicylate and the enzymes of these two pathways are independently regulated in strain VG45.
Rani
M
M
Institute of Microbial Technology, Chandigarh, India.
Prakash
D
D
Sobti
R C
RC
Jain
R K
RK
D001673:Biodegradation, Environmental; D049308:Dioxygenases; D062385:Hydroxybenzoates / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009016:Moraxella / Q000201:enzymology*; D010088:Oxidoreductases / Q000378:metabolism; D010105:Oxygenases / Q000378:metabolism; D010795:Phthalic Acids / Q000378:metabolism*; D010957:Plasmids; D012459:Salicylates / Q000378:metabolism*; D020156:Salicylic Acid
D062385:Hydroxybenzoates; D010795:Phthalic Acids; D012459:Salicylates; C009091:protocatechuic acid; C032279:phthalic acid; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D010105:Oxygenases; D049308:Dioxygenases; C026247:gentisate 1,2-dioxygenase; C022476:protocatechuate 4,5-dioxygenase; C099614:salicylic acid 5-hydroxylase; C044732:phthalate dioxygenase; C099615:4,5-dihydro-4,5-dihydroxyphthalate dehydrogenase; D020156:Salicylic Acid