title: A new analogue of nifurtimox.
abstract: 1-¿[(5-Nitro-2-furyl)methylene]amino¿-1,2,4-triazole, C7H5N5O3, is a new analogue of nifurtimox with activity against Tripanosoma cruzi. In the crystal structure, the molecule lies on a mirror plane and has an E-sZ conformation along the N = C-C moiety. The molecules are linked through C-H...O and C-H...N interactions.
authors.affiliation: Instituto de Física e Química de São Carlos, Universidade de São Paulo, Brazil.
authors.forename: I
authors.initials: I
authors.lastname: Caracelli
authors.forename: F M
authors.initials: FM
authors.lastname: Stamato
authors.forename: B
authors.initials: B
authors.lastname: Mester
authors.forename: M
authors.initials: M
authors.lastname: Paulino
authors.forename: H
authors.initials: H
authors.lastname: Cerecetto
mesh_terms: D000981:Antiprotozoal Agents / Q000737:chemistry*; D018360:Crystallography, X-Ray; D007097:Imines / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D009547:Nifurtimox / Q000031:analogs & derivatives*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D000981:Antiprotozoal Agents; D007097:Imines; D014230:Triazoles; C099741:1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole; D009547:Nifurtimox