[Is early diagnosis of amyloidosis AL possible? Consideration on a representative case].
A male patient, 53 year-old, affected by with amyloidosis AL (AAL) with MGUS IgG lambda shows the renal function and the spiro-index yet normal. There is a cardiomyopathy by amyloidosis, but the kinaemia is yet normal. We think to treat the patient with high dose therapy and PBSCs. The appearance of a heart failure and an asystole after the anaesthesia of marrow-harvest precludes this treatment: once more the diagnosis of amyloidosis AL was late. Is the early diagnosis of AAL possible?
Vivaldi
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D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D009202:Cardiomyopathies / Q000209:etiology* / Q000276:immunology; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D007146:Immunoglobulin lambda-Chains / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D009927:Tissue and Organ Procurement / Q000379:methods; D014182:Transplantation, Autologous
D007074:Immunoglobulin G; D007146:Immunoglobulin lambda-Chains
Esiste la diagnosi precoce della amiloidosi AL? Considerazioni su un caso emblematico.