title: Second messenger signalling during hormone-induced Xenopus oocyte maturation.
abstract: Although much information about such processes as cell cycle control, second messenger systems, protein kinases and steroid hormone action has been collected from studies of Xenopus oocyte maturation, we still have very little idea about how the steroid hormone, progesterone, signals the resumption of meiosis from the oocyte plasma membrane. In this review we re-examine the data on second messenger systems in Xenopus oocytes and discuss some of the unresolved questions about hormone signal transduction during maturation. We outline some reasons for the contradictions in the literature and offer some suggestions for avenues of future research.
authors.affiliation: Department of Biological Sciences, Purdue University, Indiana, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Cork
authors.forename: K R
authors.initials: KR
authors.lastname: Robinson
mesh_terms: D000818:Animals; D002453:Cell Cycle; D002462:Cell Membrane / Q000502:physiology; D005260:Female; D007328:Insulin / Q000494:pharmacology / Q000502:physiology; D008954:Models, Biological; D009865:Oocytes / Q000166:cytology* / Q000187:drug effects / Q000502:physiology*; D011374:Progesterone / Q000502:physiology*; D011980:Receptors, Progesterone / Q000502:physiology; D015290:Second Messenger Systems; D014981:Xenopus; D014982:Xenopus laevis
chemical_list: D007328:Insulin; D011980:Receptors, Progesterone; D011374:Progesterone