title: [Oxalate: its role in lithogenesis and composition of calcium oxalate lithiasis].
abstract: A prospective study was conducted on 374 patients with urinary lithiasis, aiming to analyze the participation of oxalate in the lithogenesis and composition of the calcium oxalate calculi, alone or associated to other factors.
  
  
  METHODS
  Metabolic urinary study of the patient and analysis of calculi with infrared spectrography and optical microscopy.
  
  
  RESULTS
  26.3% patients had hyperoxaluria and 77.5% of the calculi contain calcium oxalate; these are 167 cases of calcium oxalate, 110 of oxalate and calcium phosphate and 13 cases of mixed calcium oxalate and uric acid lithiasis. 43.4% patients with pure monohydrate calcium oxalate calculi have hypercalciuria, 22.6% hyperoxaluria and 19% hyperuricosuria. Dihydrated calcium oxalate calculi are related to high hypercalciuria in 65% cases and to significant hyperoxaluria in 35% cases. 45% patients present a single lithogenic factor, either hypercalciuria (49.6%), hyperoxaluria (20.6%), hyperuricosuria (13.74%), hypocitraturia (9%), urinary infection (1.5%), A.T.R. (2.25%) or acid oliguria (3%).
authors.affiliation: Servicio de Urología, Hospital Universitario de Granada.
authors.forename: A
authors.initials: A
authors.lastname: Fernandez Rodríguez
authors.forename: M
authors.initials: M
authors.lastname: Arrabal Martín
authors.forename: J F
authors.initials: JF
authors.lastname: Domínguez Molinero
authors.forename: J L
authors.initials: JL
authors.lastname: Mijan Ortiz
authors.forename: J
authors.initials: J
authors.lastname: Sánchez Tamayo
authors.forename: A
authors.initials: A
authors.lastname: Zuluaga Gómez
mesh_terms: D002129:Calcium Oxalate / Q000032:analysis*; D006801:Humans; D016015:Logistic Models; D011446:Prospective Studies; D014545:Urinary Calculi / Q000737:chemistry* / Q000209:etiology
chemical_list: D002129:Calcium Oxalate
vernacular_title: Oxalato: participación en la litogenesis y composición de la litiasis oxalocálcica.