Responses of primate taste cortex neurons to the astringent tastant tannic acid.
In order to advance knowledge of the neural control of feeding, we investigated the cortical representation of the taste of tannic acid, which produces the taste of astringency. It is a dietary component of biological importance particularly to arboreal primates. Recordings were made from 74 taste responsive neurons in the orbitofrontal cortex. Single neurons were found that were tuned to respond to 0.001 M tannic acid, and represented a subpopulation of neurons that was distinct from neurons responsive to the tastes of glucose (sweet), NaCl (salty), HCl (sour), quinine (bitter) and monosodium glutamate (umami). In addition, across the population of 74 neurons, tannic acid was as well represented as the tastes of NaCl, HCl quinine or monosodium glutamate. Multidimensional scaling analysis of the neuronal responses to the tastants indicates that tannic acid lies outside the boundaries of the four conventional taste qualities (sweet, sour, bitter and salty). Taken together these data indicate that the astringent taste of tannic acid should be considered as a taste quality, which receives a separate representation from sweet, salt, bitter and sour in the primate cortical taste areas.
Critchley
H D
HD
Department of Experimental Psychology, University of Oxford, UK.
Rolls
E T
ET
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D004594:Electrophysiology; D005947:Glucose / Q000494:pharmacology; D047348:Hydrolyzable Tannins / Q000494:pharmacology*; D008253:Macaca mulatta; D008297:Male; D009474:Neurons / Q000502:physiology*; D011803:Quinine / Q000494:pharmacology; D012965:Sodium Chloride / Q000494:pharmacology; D013649:Taste / Q000502:physiology*; D013650:Taste Buds / Q000502:physiology
D047348:Hydrolyzable Tannins; D012965:Sodium Chloride; D011803:Quinine; D005947:Glucose