title: Selection of patients for cardiac evaluation before peripheral vascular operations.
abstract: OBJECTIVE
  This study evaluated the value of preoperative cardiac screening with dipyridamole thallium scintigraphy and radionuclide ventriculography in vascular surgery patients.
  
  
  METHODS
  From July 1, 1989, to Dec. 31, 1991, we routinely (irrespective of the patient's cardiac history or symptomatology) performed dipyridamole thallium scintigraphy (DTS) and radionuclide ventriculography (RVG) in 394 patients being considered for an elective vascular operation. Patients with reversible defects on DTS underwent coronary arteriography.
  
  
  RESULTS
  DTS results were normal in 146 patients (37%), showed a fixed defect in 75 (19%), and showed a reversible defect in 173 (44%). Patients with and without a history of angina or myocardial infarction had identical rates of reversible defects. Normal left ventricular function (> 50%) was noted in 76% of the patients; 17% had moderate dysfunction (35% to 50%) and 7% had a low ejection fraction (< 35%). The finding of severe coronary artery disease led to cardiac revascularization in 17 patients who had no prior history of cardiac disease and in 13 patients with a history of angina or myocardial infarction. Two deaths and nine major complications were associated with coronary arteriography and cardiac revascularization. Vascular procedures (144 aortic, 53 carotid, 146 infrainguinal) were ultimately performed in 343 patients, with a mortality rate of 1.7% (3.5% aortic, 0% carotid, and 0.7% infrainguinal bypass). The nonfatal perioperative myocardial infarction rate was 2.0%. We monitored all 394 patients for cardiovascular events, with a mean follow-up of 40 months. Patients who underwent cardiac revascularization had a 4-year survival rate of 75%, which was similar to those with a normal DTS. Late cardiac events were significantly more frequent in patients who had either a reversible DTS or RVG < 35%.
  
  
  CONCLUSIONS
  Routine cardiac screening of vascular surgery patients had similar impact on patients irrespective of their prior history or current symptoms suggesting coronary artery disease. Routine screening did not result in substantial benefit. Screening studies such as DTS or RVG may be most useful as part of an overall risk versus benefit assessment in patients without active symptoms of coronary artery disease who have less compelling indications for vascular intervention (claudication, moderate-sized aortic aneurysms, or asymptomatic carotid disease).
authors.affiliation: Department of Surgery, University of Iowa Hospitals and Clinics, Iowa City 52242, USA.
authors.forename: M T
authors.initials: MT
authors.lastname: Schueppert
authors.forename: T F
authors.initials: TF
authors.lastname: Kresowik
authors.forename: D C
authors.initials: DC
authors.lastname: Corry
authors.forename: C
authors.initials: C
authors.lastname: Jacobovicz
authors.forename: C R
authors.initials: CR
authors.lastname: Mohan
authors.forename: E
authors.initials: E
authors.lastname: Slaymaker
authors.forename: J J
authors.initials: JJ
authors.lastname: Hoballah
authors.forename: W J
authors.initials: WJ
authors.lastname: Sharp
authors.forename: M
authors.initials: M
authors.lastname: Grover-McKay
authors.forename: J D
authors.initials: JD
authors.lastname: Corson
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology; D004176:Dipyridamole; D017558:Elective Surgical Procedures; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D018579:Patient Selection; D016491:Peripheral Vascular Diseases / Q000453:epidemiology / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D011300:Preoperative Care; D015635:Radionuclide Ventriculography; D012307:Risk Factors; D015996:Survival Rate; D013794:Thallium Radioisotopes; D013997:Time Factors; D014665:Vasodilator Agents
chemical_list: D013794:Thallium Radioisotopes; D014665:Vasodilator Agents; D004176:Dipyridamole