title: Cloning and partial structure of the gene encoding human tissue inhibitor of metalloproteinases-3.
abstract: Using a cDNA probe, two genomic clones were obtained encoding the human tissue inhibitor of metalloproteinases-3 (TIMP-3). Analysis of these clones showed that they contained four distal exons and three introns of the gene. Although the intron-exon structure is similar to that of the timp1 gene, the first intron of the timp3 gene is much longer, being at least 17.5 kb in size.
authors.affiliation: Department of Pediatrics, Childrens Hospital Los Angeles, CA 90054-0700, USA.
authors.forename: K
authors.initials: K
authors.lastname: Hammani
authors.forename: P
authors.initials: P
authors.lastname: Henriet
authors.forename: S M
authors.initials: SM
authors.lastname: Silbiger
authors.forename: Y A
authors.initials: YA
authors.lastname: DeClerck
mesh_terms: D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics*; D019717:Tissue Inhibitor of Metalloproteinase-3
chemical_list: D011506:Proteins; D019717:Tissue Inhibitor of Metalloproteinase-3; D004247:DNA