[Reversible esophageal dysfunction as a side effect of levodopa].
We are reporting the case of a 94-year-old male patient with a 10-year history of Parkinson's disease, who was admitted to our hospital with acute obstruction of esophageal passage. Esophageal obstruction was refractory to endoscopic intervention. However, discontinuation of the pre-existing levodopa medication led to its resolution within hours. While dysphagia is commonly encountered in patients with Parkinson's disease, the observed succession of drug discontinuation and resolution of obstruction in this case suggests an as yet rarely described side effect of levodopa. This potential side effect should be included in the differential diagnosis of dysphagia in Parkinson's disease, especially in the case of older patients, who may exhibit an increased rate of intestinal absorption of levodopa.
Kellner
H
H
Medizinische Poliklinik Klinikum Innenstadt, Ludwigs-Maximilians-Universität, München, Deutschland.
Liegl
U
U
Frank
M
M
Zoller
W G
WG
D000368:Aged; D000369:Aged, 80 and over; D000978:Antiparkinson Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003680:Deglutition Disorders / Q000139:chemically induced* / Q000000981:diagnostic imaging; D004940:Esophageal Stenosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D004945:Esophagoscopy; D006801:Humans; D007980:Levodopa / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy*; D011859:Radiography
D000978:Antiparkinson Agents; D007980:Levodopa
Reversible Osophagusfunktionsstörung als Nebenwirkung von Levodopa.