[S and R forms of Mycobacterium tuberculosis as a problem of producing cloned and phenotypically competent strains].
The authors suggest that animals and humans carry M. tuberculosis in S form. These mycobacteria are virulent, do not form conglomerates and represent biologically most potent form. The state of R-form M. tuberculosis results from their culturing on artificial culture media which fail to secure compatible conditions for cells. M. tuberculosis S-form is convenient for microbiological and molecular-genetic research. The authors offer a method of biological production of single M. tuberculosis in S form.
Korneev
A A
AA
Puzanov
V A
VA
Grishina
T D
TD
Chernousova
L N
LN
Kalinina
O A
OA
Musabekova
N V
NV
D003470:Culture Media; D009163:Mycobacterium bovis / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000254:growth & development* / Q000472:pathogenicity; D010641:Phenotype; D012106:Research
D003470:Culture Media
S- i R-formy Mycobacterium tuberculosis kak problema polucheniia klonirovannykh i fenotipicheski polnotsennykh shtammov.