Regression after photorefractive keratectomy for myopia.
OBJECTIVE
To evaluate the effect of topical steroid treatment in eyes that showed refractive regression after photorefractive keratectomy (PRK) to correct myopia.


METHODS
Mater Private Hospital, Dublin, Republic of Ireland.


METHODS
In this prospective study with a minimum of 6 months follow-up, 289 eyes were treated over 2 1/2 years. Of these eyes, 23 had myopic regression of 0.75 diopters (D) or more. Topical steroid treatment was given to reverse the regression. Refraction and uncorrected visual acuity before and after treatment were measured.


RESULTS
Twelve eyes in the regression group had at least 18 months of follow-up. At the final examination, eight of these eyes had an uncorrected visual acuity of 20/40 or better; six were within 1.00 D of intended refraction.


CONCLUSIONS
Refractive regression after PRK for myopia was permanently reversed in some eyes; final stable refraction was close to the intended value in about half.
Goggin
M
M
Mater Private Hospital, Dublin, Republic of Ireland.
Foley-Nolan
A
A
Algawi
K
K
O'Keefe
M
M
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001623:Betamethasone / Q000627:therapeutic use; D003315:Cornea / Q000601:surgery*; D005260:Female; D005469:Fluorometholone / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D054018:Lasers, Excimer; D008297:Male; D009216:Myopia / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D009883:Ophthalmic Solutions; D018903:Photorefractive Keratectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000188:drug therapy / Q000209:etiology*; D011446:Prospective Studies; D012008:Recurrence; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D009883:Ophthalmic Solutions; D001623:Betamethasone; D005469:Fluorometholone