Severe 5-fluorouracil toxicity possibly secondary to dihydropyrimidine dehydrogenase deficiency in a breast cancer patient with osteogenesis imperfecta.
Beuzeboc
P
P
Pierga
J Y
JY
Stoppa-Lyonnet
D
D
Etienne
M C
MC
Milano
G
G
Pouillart
P
P
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy*; D042943:Dihydrouracil Dehydrogenase (NADP); D005260:Female; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D010013:Osteogenesis Imperfecta / Q000150:complications*; D010088:Oxidoreductases / Q000172:deficiency*
D000964:Antimetabolites, Antineoplastic; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil