title: [Clinico-histological scale for identifying preinvasive lesions of the larynx].
abstract: Preinvasive laryngeal lesions progress to infiltrating carcinoma in 7-15% of cases. Clinical manifestations and histological findings are not reliably predictive of progression. Quantitative cytometry improves predictive effectiveness, but is not a routine procedure. A clinico-histological scale consisting of 13 variables which were combined and used prospectively had a predictive value of 0.8 sensitivity and 0.9 specificity for progression of preinvasive laryngeal lesions.
authors.affiliation: Servicio de ORL, Hospital Valle del Nalón. Riaño-Langreo, Asturias.
authors.forename: C A
authors.initials: CA
authors.lastname: Alvarez Marcos
authors.forename: J A
authors.initials: JA
authors.lastname: Martínez Sánchez
authors.forename: J
authors.initials: J
authors.lastname: Noval Menéndez
authors.forename: R M
authors.initials: RM
authors.lastname: Hevia Llama
authors.forename: C
authors.initials: C
authors.lastname: Suárez Nieto
authors.forename: A
authors.initials: A
authors.lastname: Sampedro Nuño
authors.forename: J R
authors.initials: JR
authors.lastname: Riera Velasco
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology*; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011446:Prospective Studies; D012189:Retrospective Studies; D012737:Sex Factors
vernacular_title: Escala clínico-histológica en el pronóstico de las lesiones preinvasivas de laringe.