Homocysteine--an atherogenic and a thrombogenic factor?
A recent study found that hyperhomocysteinemia is associated with an increased risk of extracranial carotid artery stenosis, while another study demonstrated that hyperhomocysteinemia is a common risk factor for recurrent venous thrombosis. It seems as if an elevated circulating homocysteine is atherogenic as well as thrombogenic, possibly indicating extensive involvement of homocysteine in the pathogenesis of coronary heart disease.
Ubbink
J B
JB
Department of Chemical Pathology, University of Pretoria, South Africa.
D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006710:Homocysteine / Q000097:blood* / Q000502:physiology*; D006801:Humans; D008297:Male; D012307:Risk Factors; D013924:Thrombophlebitis / Q000097:blood / Q000209:etiology* / Q000503:physiopathology
D006710:Homocysteine