[The hygienic standardization of 3-phenoxybenzyl alcohol in the atmospheric air of populated places].
The threshold level of 3-phenoxybenzyl alcohol (3-PBA) in ambient air was set up at 0.48 mg/m3. Inhalation of 3-PBA in concentrations of 4.86 and 0.518 mg/m3 caused changes in the central nervous system, metabolic processes, liver function, reduced the nonspecific resistance of the organism, and had a gonadotoxic effect. The concentration of 0.518 m3 was the threshold one, causing changes in only few of the general toxic parameters, and the 0.059 mg/m3 concentration was noneffective. The maximum permissible concentration (MPC) for 3-PBA upon a single exposure is recommended to be set up at the level of 0.2 mg/m3, the mean daily MPC at 0.06 mg/m3. By its reflex and resorptive effects the agent was referred to hazard class IV.
Iskandarova
Sh T
ShT
D000042:Absorption; D000293:Adolescent; D000328:Adult; D000393:Air Pollutants / Q000493:pharmacokinetics / Q000633:toxicity*; D000438:Alcohols / Q000493:pharmacokinetics / Q000633:toxicity*; D000818:Animals; D001592:Benzyl Alcohols / Q000493:pharmacokinetics / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D008452:Maximum Allowable Concentration; D008875:Middle Aged; D051381:Rats; D012903:Smell / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects; D013997:Time Factors
D000393:Air Pollutants; D000438:Alcohols; D001592:Benzyl Alcohols; C064809:3-phenoxybenzylalcohol
Gigienicheskoe normirovanie 3-fenoksibenzilovogo spirta v atmosfernom vozdukhe nasellennykh mest.