[Comparative study of 4 combined hormonal contraceptive preparations with reduced hormonal levels].
The authors do clinic-laboratory investigation of the affect of four hormonal contraceptive preparations: Minisston, Gravistat 125, Rigevidon, Anteovin, on 179 patients in reproductive age for the period of 895 menstrual cycles. The investigation is specified with respect of investigation of 10 clinic indexes, which are considered as side effects in the reception of hormonal contraception, as well as with respect to reconstruction of ovary function after reception breaking in first, second and third month. The received results demonstrate high effectiveness of the experimented preparations with respect to pregnancy prevention, good acceptance - the appearance of side effects is under the accidentally error limit, as well as good reproductive ability of ovaries after tablet reception breaking. Especially to Anteovin preparation the authors accept that it is with minimum side effects. They considered that this is due to increasing dose of gestagen during the second phase of the menstrual cycle, which appears stabilizing factor with respect to the good acceptance of the preparation without difference in age and fertile realization of the investigated patients.
Nalbanski
B
B
D000293:Adolescent; D000328:Adult; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000187:drug effects; D013997:Time Factors
D003277:Contraceptives, Oral, Combined
Sravnitelno prouchvane na chetiri kombinirani khormonalni kontratseptivni preparati s namaleno khormonalno nivo.