Effects of a specific neutrophil elastase inhibitor (ONO-5046 Na) and neutrophil depletion using a G-1 column on lung reperfusion injury in dogs.
Ohwada
S
S
Second Department of Surgery, Gunma University School of Medicine, Maebashi, Japan.
Tomizawa
N
N
Takahashi
T
T
Ichikawa
H
H
Kamoshita
N
N
Kobayashi
J
J
Ohya
T
T
Ogawa
T
T
Izumi
M
M
Nakamura
S
S
Iino
Y
Y
Morishita
Y
Y
D000818:Animals; D002845:Chromatography; D004285:Dogs; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006085:Graft Survival / Q000187:drug effects*; D007511:Ischemia; D007937:Leukapheresis; D007958:Leukocyte Count; D019272:Leukocyte Elastase; D008168:Lung / Q000098:blood supply*; D016040:Lung Transplantation / Q000473:pathology / Q000502:physiology*; D009504:Neutrophils / Q000502:physiology*; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors*; D015427:Reperfusion Injury / Q000517:prevention & control*; D015842:Serine Proteinase Inhibitors / Q000494:pharmacology*; D013449:Sulfonamides / Q000494:pharmacology*; D013997:Time Factors
D015842:Serine Proteinase Inhibitors; D013449:Sulfonamides; C069195:sivelestat; D010196:Pancreatic Elastase; D019272:Leukocyte Elastase; D005998:Glycine