title: Prolonged remission of SLE-associated polyradiculoneuropathy after a single course of intravenous immunoglobulin.
abstract: Polyradiculoneuropathy is a rare and potentially severe complication of systemic lupus erythematosus (SLE). Treatment is not codified and response to corticosteroid is inconstant. We report the case of a patient with severe SLE-associated polyradiculoneuropathy and autoimmune thrombocytopenia. Dramatic neurologic improvement and correction of thrombocytopenia were observed after a single course of high-dose intravenous immunoglobulin infusions (IVIg, 2g/kg body weight). Our case suggests that IVIg may be effective in the treatment of this unusual condition.
authors.affiliation: Service de Médecine Interne, Hôpital Henri Mondor, Créteil, France.
authors.forename: P
authors.initials: P
authors.lastname: Lesprit
authors.forename: F
authors.initials: F
authors.lastname: Mouloud
authors.forename: P
authors.initials: P
authors.lastname: Bierling
authors.forename: A
authors.initials: A
authors.lastname: Schaeffer
authors.forename: P
authors.initials: P
authors.lastname: Cesaro
authors.forename: C
authors.initials: C
authors.lastname: Brun-Buisson
authors.forename: B
authors.initials: B
authors.lastname: Godeau
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D011129:Polyradiculoneuropathy / Q000150:complications / Q000628:therapy*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000628:therapy; D012074:Remission Induction; D013997:Time Factors
chemical_list: D016756:Immunoglobulins, Intravenous