Development of angiosarcoma at the site of a bone infarct.
A 34-year-old man presented with angiosarcoma which developed at the site of a preexisting bone infarct in the metaphysis of the right tibia. A malignant bone tumor may develop at the site of bone infarct, and its histologic type is most frequently malignant fibrous histiocytoma or fibrosarcoma. Few patients with osteosarcoma have been reported: only 2 patients who had angiosarcoma that developed in a preexisting bone infarct have been reported in the English literature. Malignant transformation of bone infarct into angiosarcoma is extremely rare.
Matsuno
T
T
Department of Orthopaedics, Hokkaido University School of Medicine, Sapporo, Japan.
Kaneda
K
K
Takeda
N
N
D000328:Adult; D001859:Bone Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006394:Hemangiosarcoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007238:Infarction / Q000150:complications*; D008297:Male; D013977:Tibia / Q000098:blood supply*