Plasmacytoma-associated neuronal glycoprotein, Pang, maps to mouse chromosome 6 and human chromosome 3.
A new member of the immunoglobulin/fibronectin superfamily of adhesion molecules, Pang (plasmacytoma-associated neuronal glycoprotein), was recently isolated from a plasmacytoma. In previous studies, Pang was found to be normally expressed in the brain and ectopically activated by intracisternal A-type particle long terminal repeats in plasmacytomas. In this study, Pang was initially mapped to mouse Chr 6 by somatic cell hybrid analysis and further positioned on the chromosome between Wnt7a and Pcp1. Southern blot analysis of human-rodent somatic cell hybrids together with predictions from the mouse map location indicate that human PANG is located at 3p26.
Mock
B A
BA
Laboratory of Genetics, NIH, Bethesda, Maryland, 20892-4255, USA.
Connelly
M A
MA
McBride
O W
OW
Kozak
C A
CA
Marcu
K B
KB
D000818:Animals; D001921:Brain / Q000378:metabolism; D015816:Cell Adhesion Molecules, Neuronal / Q000096:biosynthesis / Q000235:genetics*; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D058966:Contactins; D006224:Cricetinae; D003412:Cricetulus; D003433:Crosses, Genetic; D007426:Genes, Intracisternal A-Particle; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D009115:Muridae; D009363:Neoplasm Proteins / Q000235:genetics; D010954:Plasmacytoma / Q000235:genetics / Q000378:metabolism; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping
C484185:CNTN3 protein, human; D015816:Cell Adhesion Molecules, Neuronal; C085907:Cntn3 protein, mouse; D058966:Contactins; D005819:Genetic Markers; D009363:Neoplasm Proteins