title: The presence of Epstein-Barr virus in multiple organs in a fatal case of virus-associated haemophagocytic syndrome.
abstract: We describe a case report of a 21-year-old male with fatal Epstein-Barr virus-associated haemophagocytic syndrome. Virus is detected in multiple organs by polymerase chain reaction and in the tissue-specific cells of those organs by in situ hybridisation. It is suggested that organ failure may be a direct response to infection.
authors.affiliation: Department of Pathology, University of Leicester Medical School, U.K.
authors.forename: J H
authors.initials: JH
authors.lastname: Pringle
authors.forename: L
authors.initials: L
authors.lastname: Primrose
authors.forename: S H
authors.initials: SH
authors.lastname: Myint
mesh_terms: D000328:Adult; D001483:Base Sequence; D017809:Fatal Outcome; D006566:Herpesviridae Infections / Q000821:virology*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000821:virology*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data