title: Structures of new acidic O-specific polysaccharides of the bacterium Proteus mirabilis serogroups O26 and O30.
abstract: The polysaccharide chains of the lipopolysaccharides of the Proteus mirabilis serogroups O26 and O30 were studied using sugar and methylation analysis and 1H and 13C NMR spectroscopy, including two-dimensional correlation spectroscopy and rotating-frame NOE spectroscopy. The polysaccharides were found to be acidic due to the presence of D-galacturonic acid and its amide with L-lysine in serogroup O26 or D-glucuronic acid in serogroup O30, and the structures of their tetrasaccharide repeating units were established. The O26-specific polysaccharide is structurally and serologically related to the O-specific polysaccharide of P. mirabilis O28, which includes amides of D-GalA with L-lysine and L-serine [Radziejewska-Lebrecht, J. et al. (1995) Eur. J. Biochem. 230, 705-712].
authors.affiliation: N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia.
authors.forename: A S
authors.initials: AS
authors.lastname: Shashkov
authors.forename: F V
authors.initials: FV
authors.lastname: Toukach
authors.forename: N A
authors.initials: NA
authors.lastname: Paramonov
authors.forename: A
authors.initials: A
authors.lastname: Ziolkowski
authors.forename: S N
authors.initials: SN
authors.lastname: Senchenkova
authors.forename: W
authors.initials: W
authors.lastname: Kaca
authors.forename: Y A
authors.initials: YA
authors.lastname: Knirel
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D019081:O Antigens / Q000737:chemistry*; D011513:Proteus mirabilis / Q000737:chemistry* / Q000145:classification; D012703:Serotyping
chemical_list: D019081:O Antigens