title: Anomalies in the permanent dentition and other oral findings in 29 individuals with Laurence-Moon-Bardet-Biedl syndrome.
abstract: This paper reports a clinical and roentgenological examination of the teeth, jaws and saliva of 29 Scandinavian individuals with Laurence-Moon-Bardet-Biedl (LMBB) syndrome, whose cardinal signs are retinal dystrophy, polydactyly, obesity, hypogenitalism and mental retardation. All subjects had at least three of these signs, including retinal dystrophy. Compared with normal subjects, the group had statistically significantly higher frequencies of hypodontia, small teeth and short roots. In addition, the saliva showed a buffering capacity higher than normal. In conclusion, there seem to exist disturbances of both dental and skeletal formation in the LMBB syndrome.
authors.affiliation: Department of Pedodontics, Lund University, School of Dentistry, Malmö, Sweden.
authors.forename: M K
authors.initials: MK
authors.lastname: Borgström
authors.forename: R
authors.initials: R
authors.lastname: Riise
authors.forename: K
authors.initials: K
authors.lastname: Tornqvist
authors.forename: L
authors.initials: L
authors.lastname: Granath
mesh_terms: D000293:Adolescent; D000328:Adult; D000848:Anodontia / Q000473:pathology; D002021:Buffers; D002648:Child; D006801:Humans; D007569:Jaw Abnormalities / Q000473:pathology; D007849:Laurence-Moon Syndrome / Q000473:pathology* / Q000503:physiopathology; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism / Q000502:physiology; D012636:Secretory Rate; D014071:Tooth Abnormalities / Q000473:pathology*; D014092:Tooth Root / Q000002:abnormalities / Q000473:pathology
chemical_list: D002021:Buffers