title: Sequence of the bchG gene from Chloroflexus aurantiacus: relationship between chlorophyll synthase and other polyprenyltransferases.
abstract: The sequence of the Chloroflexus aurantiacus open reading frame thought to be the C. aurantiacus homolog of the Rhodobacter capsulatus bchG gene is reported. The BchG gene product catalyzes esterification of bacteriochlorophyllide a by geranylgeraniol-PPi during bacteriochlorophyll a biosynthesis. Homologs from Arabidopsis thaliana, Synechocystis sp. strain PCC6803, and C. aurantiacus were identified in database searches. Profile analysis identified three related polyprenyltransferase enzymes which attach an aliphatic alcohol PPi to an aromatic substrate. This suggests a broader relationship between chlorophyll synthases and other polyprenyltransferases.
authors.affiliation: Department of Chemistry and Biochemistry, Center for the Study of Early Events in Photosynthesis, Arizona State University, Tempe, 85287-1604, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Lopez
authors.forename: S
authors.initials: S
authors.lastname: Ryan
authors.forename: R E
authors.initials: RE
authors.lastname: Blankenship
mesh_terms: D000595:Amino Acid Sequence; D001419:Bacteria / Q000235:genetics / Q000378:metabolism*; D001426:Bacterial Proteins / Q000096:biosynthesis*; D001483:Base Sequence; D002734:Chlorophyll / Q000096:biosynthesis*; D004122:Dimethylallyltranstransferase / Q000737:chemistry*; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D005810:Multigene Family; D010788:Photosynthesis
chemical_list: D001426:Bacterial Proteins; C026083:bacteriochlorophyll A proteins, Bacteria; D002734:Chlorophyll; D004122:Dimethylallyltranstransferase