Sensitivity to augmentin and cephalosporines of some bacterial strains isolated from hospitalized patients.
The study allowed the determination of the degree of antibacterial efficiency of three antimicrobial agents belonging to the betalactamine family namely cefuroxime (IInd generation), ceftazidime (IIIrd generation) and augmentin. Likewise the relationship bacterial species-antibiotic could be established. It was found that the pathogenic staphylococcus strains were very sensitive to cefuroxime (92.1%) and equally sensitive to ceftazidime and augmentin (61.0%). The enterococci were 100% sensitive to augmentin and 100% resistant to both cephalosporines. The enterobacteriaceae presented a higher percentage of sensitive strains to cephalosporines than to augmentin 89.6% of the E. coli strains were sensitive to ceftazidime, 77.9% to cefuroxime and 27.3% to augmentin. Klebsiella was sensitive in 68.2%, 45.14% and 13.6% of the cases to ceftazidime, cefuroxime and respectively augmentin. Proteus presented 64.7% strains sensitive to ceftazidime, 35.3% sensitive to cefuroxime and 29.3% sensitive to augmentin. All the enterobacter strains proved resistant to the three antibiotics studied.
Debeleac
L
L
Carol Davila University of Medicine and Pharmacy, Bucharest University Hospital, Romania.
Iancu
A
A
Tudorache
D
D
Iancu
G
G
D000658:Amoxicillin / Q000494:pharmacology; D019980:Amoxicillin-Potassium Clavulanate Combination; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D002511:Cephalosporins / Q000494:pharmacology*; D002969:Clavulanic Acids / Q000494:pharmacology; D004359:Drug Therapy, Combination / Q000494:pharmacology*; D006760:Hospitalization; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data; D012383:Romania
D002511:Cephalosporins; D002969:Clavulanic Acids; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin