title: Assignment of the human ST2 gene to chromosome 2 at q11.2.
abstract: The human St2 locus has been assigned to chromosome 2, using a human ST2 cDNA clone, by a human/rodent somatic cel hybrid mapping panel. The St2 locus has also been mapped to chromosome 2q11.2, using a human ST2 genomic DNA clone, by in situ hybridization. The locus is very tightly linked to the Il-1r1 locus. Together with the structural similarity of ST2 to IL-1RI, these data suggest functional relationships between these two genes.
authors.affiliation: Department of Biochemistry II, Jichi Medical School, Tochigi, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Tominaga
authors.forename: J
authors.initials: J
authors.lastname: Inazawa
authors.forename: S
authors.initials: S
authors.lastname: Tsuji
mesh_terms: D000818:Animals; D016466:CHO Cells; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D006224:Cricetinae; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D000072179:Interleukin-1 Receptor-Like 1 Protein; D008565:Membrane Proteins; D014176:Protein Biosynthesis; D011506:Proteins / Q000235:genetics*; D011956:Receptors, Cell Surface; D011994:Recombinant Proteins / Q000096:biosynthesis; D012377:Rodentia
chemical_list: C079241:IL1RL1 protein, human; D000072179:Interleukin-1 Receptor-Like 1 Protein; D008565:Membrane Proteins; D011506:Proteins; D011956:Receptors, Cell Surface; D011994:Recombinant Proteins