Growth rate of lung metastases and S-phase fraction as determined by flow cytometry from the primary tumour in 25 patients with bone or soft-tissue sarcomas.
A significant correlation (r = -0.48) was found between the logarithm of the S-phase fraction of the primary tumour (SPF) and the logarithm of the doubling time of lung metastases (T2). The estimated median cell loss factor was 88% (range 35-99%).
Blomqvist
C
C
Department of Radiotherapy and Oncology, University of Helsinki, Finland.
Huuhtanen
R
R
Pan
Y
Y
Wiklund
T
T
Tarkkanen
M
M
Virolainen
M
M
Tribukait
B
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology*; D002455:Cell Division / Q000502:physiology; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D016196:S Phase / Q000502:physiology*; D012509:Sarcoma / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology*