The human intron-containing gene for glycogenin maps to chromosome 3, band q24.
Glycogenin is the autocatalytic, self-glucosylating primer for glycogen synthesis, providing the anchor on which the macromolecule is constructed. We have sequenced the cDNA coding for human muscle glycogenin and have deduced the corresponding amino acid sequence. By means of the polymerase chain reaction and fluorescence in situ hybridization, we have found the chromosomal location of the gene coding for glycogenin. This is localized to human chromosome 3, band q24.
Lomako
J
J
Department of Biochemistry and Molecular Biology, University of Miami School of Medicine, Miami, Florida, 33101, USA.
Mazuruk
K
K
Lomako
W M
WM
Alonso
M D
MD
Whelan
W J
WJ
Rodriguez
I R
IR
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D006224:Cricetinae; D017931:DNA Primers; D018076:DNA, Complementary; D005964:Glucosyltransferases; D006023:Glycoproteins / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007438:Introns; D051379:Mice; D008969:Molecular Sequence Data; D018482:Muscle, Skeletal / Q000378:metabolism; D016133:Polymerase Chain Reaction
D017931:DNA Primers; D018076:DNA, Complementary; D006023:Glycoproteins; C051887:glycogenin; D005964:Glucosyltransferases