title: Cytologic appearance of sinus histiocytosis with massive lymphadenopathy: a case report.
abstract: BACKGROUND
  Sinus histiocytosis with massive lymphadenopathy is a benign, massive lymphadenopathy, usually cervical, of unknown etiology.
  
  
  METHODS
  Cytologic smears revealed a polymorphic population of cells consisting of mature lymphocytes, plasma cells, occasional neutrophils and many histiocytes, characteristically showing emperipolesis. A reactive lymphadenopathy was diagnosed. The histopathologic diagnosis on open biopsy specimen was sinus histiocytosis with massive lymphadenopathy.
  
  
  CONCLUSIONS
  Cytologic diagnosis of sinus histiocytosis with massive lymphadenopathy is possible with high accuracy provided that the cytologic findings are interpreted in the appropriate clinical context. The cytologic examination also can help with follow-up.
authors.affiliation: Department of Pathology, Cancer Hospital and Research Institute, Gwailor, Madhya Pradesh, India.
authors.forename: S
authors.initials: S
authors.lastname: Gupta
authors.forename: D C
authors.initials: DC
authors.lastname: Gupta
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D015618:Histiocytosis, Sinus / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000150:complications / Q000175:diagnosis; D008223:Lymphoma / Q000175:diagnosis; D008297:Male