Dichloroacetate increases cell and product yields in hybridoma batch cultures.
Murray
K
K
Biochemistry Research Division, School of Biological Sciences, University of Manchester, Oxford, U.K.
Gull
K
K
Dickson
A J
AJ
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis; D002455:Cell Division / Q000187:drug effects; D003999:Dichloroacetic Acid / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D005973:Glutamine / Q000378:metabolism; D006825:Hybridomas / Q000187:drug effects* / Q000276:immunology / Q000378:metabolism; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism
D000911:Antibodies, Monoclonal; D011768:Pyruvate Dehydrogenase Complex; D005973:Glutamine; D003999:Dichloroacetic Acid