[New aspects in the etiopathogenesis of colorectal cancer].
Proceeding from a comprehensive literature review, the new aspects of the etiopathogenesis of colorectal carcinoma are presented for the first time in this country. The updated etiopathogenetic postulates in cancerogenesis are discussed, namely: the low calcium diet is associated with carcinoma of the colon, fecapentaens are mutagens found in the feces, produced by intestinal flora against the background of dysbacteriosis, triketosteroids at high concentrations are found in populations at risk of carcinoma of the colon, free bile acids in the faces play a major role in the genesis of carcinoma of the colon, serum cholesterol and beta-lipoproteins are directly linked to carcinoma of the colon-a decrease in serum, cholesterol level is noted in patients with colorectal carcinoma. The finding of a definite gen in 17 and 18 chromosomes, having a tumor-suppressive and mutagenic effect, is the most important examination in the field of molecular biology.
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D002886:Chromosomes, Human, Pair 17; D002887:Chromosomes, Human, Pair 18; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D012307:Risk Factors
Novi aspekti v etio-patogenezata na kolo-rektalniia rak.