title: A ROC study of AMBER and conventional chest imaging in the detection of simulated interstitial lung disease.
abstract: OBJECTIVE
  The aim of this study was to compare the detection of simulated interstitial lung disease with Advanced Multiple Beam Equalization Radiography (AMBER) and conventional wide latitude screen-film radiography.
  
  
  METHODS
  Interstitial disease of varying severity was simulated with overlays on an anthropomorphic chest phantom. A total of 60 images per modality was used in a Receiver Operating Characteristic (ROC) study.
  
  
  RESULTS
  AMBER performed significantly better than conventional radiography for all readers (P < 0.02). The difference was even more significant for the radiologist readers (P = 0.001). In each case the difference in ROC areas was between 5% and 9%.
  
  
  CONCLUSIONS
  AMBER is superior to conventional wide latitude screen-film imaging in detecting the subtle patterns used to simulate interstitial lung disease.
authors.affiliation: Department of Radiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
authors.forename: I H
authors.initials: IH
authors.lastname: van Schelven
authors.forename: L H
authors.initials: LH
authors.lastname: Winter
authors.forename: D P
authors.initials: DP
authors.lastname: Chakraborty
authors.forename: L J
authors.initials: LJ
authors.lastname: Schultze Kool
mesh_terms: D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008953:Models, Anatomic; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging*; D012372:ROC Curve; D011856:Radiographic Image Enhancement / Q000295:instrumentation*; D014963:X-Ray Intensifying Screens