title: Pk92B: a Drosophila melanogaster protein kinase that belongs to the MEKK family.
abstract: A Drosophila melanogaster cDNA, encoding a protein with sequence similarity to the MEKK family of Ser/Thr kinases, was isolated from an eye-antennal imaginal disc cDNA library using a PCR-based approach. The deduced protein, Pk92B, has a kinase domain that is 40-48% identical to MEKK family members. The Pk92B gene was mapped to 92B8-10 on the third chromosome by in situ hybridization to polytene chromosomes.
authors.affiliation: Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California at Berkeley, 94720-3200, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Wassarman
authors.forename: N M
authors.initials: NM
authors.lastname: Solomon
authors.forename: G M
authors.initials: GM
authors.lastname: Rubin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002874:Chromosome Mapping; D018076:DNA, Complementary; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000201:enzymology*; D020930:MAP Kinase Kinase Kinases; D008969:Molecular Sequence Data; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry* / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; D029721:Drosophila Proteins; D017346:Protein Serine-Threonine Kinases; C099707:ASK1 protein, Drosophila; D020930:MAP Kinase Kinase Kinases