Constrictive bronchiolitis obliterans following gold therapy for psoriatic arthritis.
A 41 year old male with psoriatic arthritis developed progressive dyspnoea and airflow obstruction following 4 months of intramuscular gold therapy. Open lung biopsy revealed bronchiolitis obliterans of the constrictive type. This case suggests a possible aetiological role for gold in the pathogenesis of constrictive bronchiolitis obliterans, or alternatively an association between psoriatic arthritis and this inflammatory airway condition.
Schwartzman
K J
KJ
Dept of Medicine, Royal Victoria Hospital, Montreal, Quebec, Canada.
Bowie
D M
DM
Yeadon
C
C
Fraser
R
R
Sutton
E D
ED
Levy
R D
RD
D000328:Adult; D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D015535:Arthritis, Psoriatic / Q000188:drug therapy*; D001706:Biopsy; D001989:Bronchiolitis Obliterans / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D050607:Organogold Compounds
D018501:Antirheumatic Agents; D050607:Organogold Compounds