title: Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
abstract: The complete nucleotide sequence of Saccharomyces cerevisiae chromosome X (745 442 bp) reveals a total of 379 open reading frames (ORFs), the coding region covering approximately 75% of the entire sequence. One hundred and eighteen ORFs (31%) correspond to genes previously identified in S. cerevisiae. All other ORFs represent novel putative yeast genes, whose function will have to be determined experimentally. However, 57 of the latter subset (another 15% of the total) encode proteins that show significant analogy to proteins of known function from yeast or other organisms. The remaining ORFs, exhibiting no significant similarity to any known sequence, amount to 54% of the total. General features of chromosome X are also reported, with emphasis on the nucleotide frequency distribution in the environment of the ATG and stop codons, the possible coding capacity of at least some of the small ORFs (<100 codons) and the significance of 46 non-canonical or unpaired nucleotides in the stems of some of the 24 tRNA genes recognized on this chromosome.
authors.affiliation: CNRS Recombinaisons Génétiques, Faculté de Médecine, Rennes, France.
authors.forename: F
authors.initials: F
authors.lastname: Galibert
authors.forename: D
authors.initials: D
authors.lastname: Alexandraki
authors.forename: A
authors.initials: A
authors.lastname: Baur
authors.forename: E
authors.initials: E
authors.lastname: Boles
authors.forename: N
authors.initials: N
authors.lastname: Chalwatzis
authors.forename: J C
authors.initials: JC
authors.lastname: Chuat
authors.forename: F
authors.initials: F
authors.lastname: Coster
authors.forename: C
authors.initials: C
authors.lastname: Cziepluch
authors.forename: M
authors.initials: M
authors.lastname: De Haan
authors.forename: H
authors.initials: H
authors.lastname: Domdey
authors.forename: P
authors.initials: P
authors.lastname: Durand
authors.forename: K D
authors.initials: KD
authors.lastname: Entian
authors.forename: M
authors.initials: M
authors.lastname: Gatius
authors.forename: A
authors.initials: A
authors.lastname: Goffeau
authors.forename: L A
authors.initials: LA
authors.lastname: Grivell
authors.forename: A
authors.initials: A
authors.lastname: Hennemann
authors.forename: C J
authors.initials: CJ
authors.lastname: Herbert
authors.forename: K
authors.initials: K
authors.lastname: Heumann
authors.forename: F
authors.initials: F
authors.lastname: Hilger
authors.forename: C P
authors.initials: CP
authors.lastname: Hollenberg
authors.forename: M E
authors.initials: ME
authors.lastname: Huang
authors.forename: C
authors.initials: C
authors.lastname: Jacq
authors.forename: J C
authors.initials: JC
authors.lastname: Jauniaux
authors.forename: C
authors.initials: C
authors.lastname: Katsoulou
authors.forename: L
authors.initials: L
authors.lastname: Karpfinger-Hartl
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002503:Centromere; D002874:Chromosome Mapping; D015825:Chromosomes, Fungal; D018388:Codon, Terminator; D008969:Molecular Sequence Data; D005810:Multigene Family; D016366:Open Reading Frames; D012343:RNA, Transfer / Q000737:chemistry; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D016615:Telomere
chemical_list: D018388:Codon, Terminator; D012343:RNA, Transfer