title: Precocious puberty with pituitary gland hyperplasia: two cases in one family.
abstract: Children with central precocious puberty have pituitary gland size comparable to that of pubertal children (pituitary gland height 6.1 +/- 1.1 mm). We present of two sisters with precocious puberty and a pituitary gland height of more than 1 cm. On contrast enhanced MRI, there was homogeneous enhancement of the pituitary gland. There was no increase in pituitary gland size during the follow-up period (6 years and 2 years). These cases are reported for their rarity.
authors.affiliation: Department of Radiology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Gupta
authors.forename: A C
authors.initials: AC
authors.lastname: Ammini
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008279:Magnetic Resonance Imaging; D010902:Pituitary Gland / Q000473:pathology*; D011629:Puberty, Precocious / Q000150:complications / Q000235:genetics* / Q000473:pathology