[The lipid peroxidation level and antioxidant status of the plasma in patients operated on under propofol (Diprivan) anesthesia].
It has been investigated the level of lipid peroxidation and antioxidant status of blood plasma from patients operated under general anaesthesia with propofol (Diprivan). The following parameters have been registered: TBA-reactive substances (TBARS) and fluorescent lipofuscine-like lipid peroxidation products, before, directly after and 24 hours after anaesthesia. It was not shown statistically significant changes of TBARS before and after anaesthesia. The levels of TBARS were initially higher in comparison of referent levels. The fluorescent lipofuscine-like products were increased weakly after anaesthesia directly but the changes were not statistically significant, too. The antioxidant capacity of blood plasma was decreased weakly 24 hours after anaesthesia, in comparison of the levels, registered before anaesthesia. The good correlation between fluorescent products and antioxidant status of plasma was observed.
Khinev
S
S
Dafinova
K
K
Tenchova
V
V
Bakalova
R
R
D000704:Analysis of Variance; D018686:Anesthetics, Intravenous; D000975:Antioxidants / Q000378:metabolism*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008054:Lipid Peroxides / Q000097:blood; D008297:Male; D011229:Preanesthetic Medication; D015742:Propofol; D013514:Surgical Procedures, Operative / Q000706:statistics & numerical data
D018686:Anesthetics, Intravenous; D000975:Antioxidants; D008054:Lipid Peroxides; D015742:Propofol
Nivo na lipidnata peroksidatsiia i antioksidanten status na plazmata na patsienti, operirani pod anesteziia s propofol (diprivan).