title: [Biochemical changes in extracellular matrix components of the amniotic sac during its premature rupture].
abstract: In the fetal membranes that have ruptured 12 hours before onset of the labour the tissue collagen content was lower than in control accompanying by similar local collagenase and elastase activity. These results excluded the inflammatory process as the main cause of prelabour preterm rupture of membranes (PPROM). The analysis of the collagen fractions taken from the site of rupture and the location close to umbilical cord indicates that in PPROM there are changes in posttranslational collagen molecule modification.
authors.affiliation: II Kliniki Ginekologii Operacyjnej AM w Lublinie.
authors.forename: T
authors.initials: T
authors.lastname: Rechberger
authors.forename: K
authors.initials: K
authors.lastname: Postawski
authors.forename: H
authors.initials: H
authors.lastname: Donica
authors.forename: L
authors.initials: L
authors.lastname: Surmacz
authors.forename: J
authors.initials: J
authors.lastname: Jakowicki
mesh_terms: D000328:Adult; D000650:Amnion / Q000378:metabolism*; D003094:Collagen / Q000032:analysis*; D017364:Collagenases / Q000378:metabolism; D005109:Extracellular Matrix / Q000378:metabolism*; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000378:metabolism*; D006801:Humans; D006909:Hydroxyproline / Q000378:metabolism; D010196:Pancreatic Elastase / Q000378:metabolism; D011247:Pregnancy
chemical_list: D003094:Collagen; D010196:Pancreatic Elastase; D017364:Collagenases; D006909:Hydroxyproline
vernacular_title: Zmiany biochemiczne macierzy zewnatrzkomórkowej błon płodowych przy ich przedwczesnym pekaniu.