[Caffeine antagonizes the neuromuscular blockade of vecuronium].
It is known that theophylline antagonizes the neuromuscular blockade in animals and case reports, where the same phenomenon has been observed in man, are described. One patient is described where another methylxantine-caffeine-caused resistance to neuromuscular blockade by vecuronium, but successful blockade was achieved by pancuronium.
Weitling
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EE
Anaestesi- og intensivafdelingen, Sønderborg Sygehus.
D000328:Adult; D002110:Caffeine / Q000494:pharmacology*; D000697:Central Nervous System Stimulants / Q000494:pharmacology*; D003069:Coffee; D005260:Female; D006801:Humans; D003473:Neuromuscular Nondepolarizing Agents / Q000037:antagonists & inhibitors*; D014673:Vecuronium Bromide / Q000037:antagonists & inhibitors*
D000697:Central Nervous System Stimulants; D003069:Coffee; D003473:Neuromuscular Nondepolarizing Agents; D002110:Caffeine; D014673:Vecuronium Bromide
Koffein virker antagonistisk på den neuromuskulaere blokade af vecuronium.