title: Posterior segment neovascularization associated with optic nerve aplasia.
abstract: OBJECTIVE
  To report the presence of posterior segment neovascularization in eyes with optic nerve aplasia.
  
  
  METHODS
  Three eyes in two patients with clinical optic nerve aplasia were studied.
  
  
  RESULTS
  Examination disclosed posterior segment neovascularization in one eye and progressive posterior segment neovascularization in two eyes.
  
  
  CONCLUSIONS
  Posterior segment neovascularization may occur in association with optic nerve aplasia. Retinal ischemia or retinochoroidal anatomic disorganization, or both, may provide the stimulus for neovascularization in such eyes.
authors.affiliation: Department of Ophthalmology, Jules Stein Eye Institute, University of California Los Angeles School of Medicine 90095-7000, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Lee
authors.forename: J B
authors.initials: JB
authors.lastname: Bateman
authors.forename: S D
authors.initials: SD
authors.lastname: Schwartz
mesh_terms: D003103:Coloboma / Q000209:etiology; D004596:Electroretinography; D005260:Female; D006801:Humans; D007223:Infant; D007498:Iris / Q000002:abnormalities; D008297:Male; D008850:Microphthalmos / Q000209:etiology; D009898:Optic Disk / Q000002:abnormalities; D009900:Optic Nerve / Q000002:abnormalities*; D012166:Retinal Hemorrhage / Q000209:etiology / Q000473:pathology; D015861:Retinal Neovascularization / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D014823:Vitreous Hemorrhage / Q000209:etiology / Q000473:pathology