title: [32 years of Senning's correction for transposition of the great vessels].
abstract: Between 1962 and 1994 342 patients with transposition of the great arteries (TGA) were treated by atrial correction. Since 1992 the atrial switch operation is the treatment of choice for TGA. We reviewed our 32 year experience. Average age of the patients at operation was 69 months (7 days--8.5 years). 177/342 (52%) patients had a complex TGA: 74 patients with ventricular septal defect (VSD), 49 patients with pulmonary stenosis (PS) and 54 with both (VSD and PS). The 30 day mortality was for the whole series 15.7%. In the last 4 years 7.5%. The actuarial survival rate for all patients was 88% after 10 years and 82% after 20 years. For simple TGA 91% after 10 years and 83% after 20 years, for complex TGA 84% and 81%. The most important cause of death during our longterm observation were heart failure (19 patients) and sudden death (7 patients). Average follow-up for the whole group was 13.4 years. Most of the survivors are functionally symptom free (66% NYHA I) or they have slight symptoms (29% NYHA II). Only 5% were NYHA III or IV. Arterial switch operation has replaced the atrial correction for TGA. Nevertheless the longterm results after atrial correction remains encouraging. The main threat to the patients is the failure of the systemic ventricle.
authors.affiliation: Klinik für Herzchirurgie, Universitätsspital Zürich.
authors.forename: M
authors.initials: M
authors.lastname: Genoni
authors.forename: L
authors.initials: L
authors.lastname: von Segesser
authors.forename: M
authors.initials: M
authors.lastname: Wilhelm
authors.forename: U
authors.initials: U
authors.lastname: Arbenz
authors.forename: M
authors.initials: M
authors.lastname: Turina
mesh_terms: D006348:Cardiac Surgical Procedures / Q000379:methods; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D016757:Death, Sudden, Cardiac; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012189:Retrospective Studies; D015996:Survival Rate; D014188:Transposition of Great Vessels / Q000150:complications / Q000401:mortality / Q000601:surgery*
vernacular_title: 32 Jahre Vorhofsumkehr nach Senning.