title: A Dutch population study of the STR Loci HUMTHO1, HUMFES/FPS, HUMVWA31/1 and HUMF13A1, conducted for forensic purposes.
abstract: We report on a Dutch population study of the STR loci HUMTHO1, HUMFES/FPS, HUMVWA31/1, and HUMF13A1, in which we used multiplex amplification and automated fragment detection. Genotype and allele frequencies showed no deviation from Hardy-Weinberg and linkage equilibrium. The improved Bonferroni procedure was used to combine the results of several tests. The power of discrimination of a complete profile exceeded 0.9998. We compared the allele frequencies in the Dutch sample to the frequencies in other populations using a bipilot to visualize alleles and populations simultaneously. The Dutch sample was similar to most other Caucasian samples. The data demonstrate that the genetic systems in this report are a valuable tool for forensic identity testing in The Netherlands.
authors.affiliation: Netherlands Forensic Science Institute, Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Sjerps
authors.forename: N
authors.initials: N
authors.lastname: van der Geest
authors.forename: C
authors.initials: C
authors.lastname: Pieron
authors.forename: M
authors.initials: M
authors.lastname: Gajadhar
authors.forename: A
authors.initials: A
authors.lastname: Kloosterman
mesh_terms: D005006:Ethnicity; D005554:Forensic Medicine; D005787:Gene Frequency / Q000235:genetics*; D005819:Genetic Markers / Q000235:genetics; D005828:Genetics, Population; D006579:Heterozygote; D006801:Humans; D016013:Likelihood Functions; D015810:Linkage Disequilibrium; D009426:Netherlands; D016133:Polymerase Chain Reaction / Q000379:methods; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D044465:White People
chemical_list: D005819:Genetic Markers