title: Systemic treatment of cancer.
abstract: For the past 50 years, the search has continued for systematically administered agents that can produce profound and lasting effects on human cancers. This has led to the use of many cytoxically and hormonally active agents and, more recently, to the use of biologic agents. The author presents the 10th in a series of periodic updates in this journal on the current status of systematic treatment of cancer.
authors.affiliation: University of Texas, MD Anderson Cancer Center, Houston, USA.
authors.forename: I H
authors.initials: IH
authors.lastname: Krakoff
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001688:Biological Products / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D009369:Neoplasms / Q000401:mortality / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents; D001688:Biological Products