A mucoepidermoid carcinoma of minor salivary gland with t(11;19)(q21;p13.1) as the only karyotypic abnormality.
We present the cytogenetic analysis of a mucoepidermoid carcinoma of the minor salivary gland with t(11,19)(q21;p13.1) as the sole karyotypic abnormality. Our findings, along with those of previous reports, indicate that this translocation is an early and most likely a primary event in the development of a least a subset of these neoplasms.
El-Naggar
A K
AK
Department of Pathology, University of Texas, M.D. Anderson Cancer Center, Houston 77030, USA.
Lovell
M
M
Killary
A M
AM
Clayman
G L
GL
Batsakis
J G
JG
D000293:Adolescent; D018277:Carcinoma, Mucoepidermoid / Q000235:genetics*; D002880:Chromosomes, Human, Pair 11; D002888:Chromosomes, Human, Pair 19; D005260:Female; D006801:Humans; D012468:Salivary Gland Neoplasms / Q000235:genetics* / Q000473:pathology; D012470:Salivary Glands, Minor; D014178:Translocation, Genetic