title: Carbon dioxide pneumothorax in laparoscopic surgery.
abstract: BACKGROUND
  We conducted this animal study to investigate the cardiopulmonary effects of carbon dioxide pneumothorax during laparoscopic surgery and determine what intervention, if any, is necessary for this phenomenon.
  
  
  METHODS
  A swine animal model was used (n = 8). Animals were anesthetized and underwent peritoneal insufflation with carbon dioxide. A laceration was created in the left diaphragm. pO2, pCO2, oxygen saturation, peak inspiratory pressure (PIP), systolic blood pressure, and heart rate were measured and subjected to statistical analysis.
  
  
  RESULTS
  Significant changes were noted in the pO2, O2 saturation, pCO2, and PIP upon creation of the pneumothorax. Trends were also noted in the heart rate and the systolic blood pressure. The physiologic changes could be corrected by noninvasive means and without terminating the procedure.
  
  
  CONCLUSIONS
  Carbon dioxide pneumothorax produces reproducible cardiopulmonary changes in laparoscopic surgery. These changes are easily monitored and the resulting cardiopulmonary changes can be treated without invasive means.
authors.affiliation: Department of Minimally Invasive-Surgery, Legacy Portland Hospitals, Oregon, USA.
authors.forename: D R
authors.initials: DR
authors.lastname: Marcus
authors.forename: W M
authors.initials: WM
authors.lastname: Lau
authors.forename: L L
authors.initials: LL
authors.lastname: Swanstrom
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D004195:Disease Models, Animal; D010535:Laparoscopy / Q000009:adverse effects*; D011030:Pneumothorax / Q000209:etiology* / Q000503:physiopathology*; D012123:Pulmonary Ventilation; D012119:Respiration; D013552:Swine
chemical_list: D002245:Carbon Dioxide