[Monoclonal free light-chain immunoglobulins: their clinical interpretation].
23 cases of free light chains (FLC) occurrence in the blood and/or urine in the absence of monoclonal gammopathy are reported. Of them 15 cases were attributed to renal diseases associated with deranged catabolism of low-molecular proteins including FLC. In the rest cases FLC hyperproduction in autoimmune diseases was suspected to cause FLC appearance. No correlation was found between the amounts of FLC, creatinine, beta 2-microglobulin, light chains, kappa/lambda proportions.
Reznikov
Iu P
IuP
Kamaeva
O I
OI
Pimenova
N S
NS
D000328:Adult; D000368:Aged; D001327:Autoimmune Diseases / Q000175:diagnosis; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis; D005779:Immunodiffusion; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007147:Immunoglobulin Light Chains / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D007674:Kidney Diseases / Q000175:diagnosis; D008875:Middle Aged; D012189:Retrospective Studies
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D007075:Immunoglobulin M
Monoklonal'nye svobodnye legkie tsepi immunoglobulinov: klinicheskaia interpretatsiia.