Stability of bupivacaine hydrochloride and hydromorphone hydrochloride during simulated epidural coadministration.
Bupivacaine hydrochloride 625 and 1250 micrograms/mL and hydromorphone hydrochloride 20 and 100 micrograms/mL in 0.9% sodium chloride injection were stable and compatible for up to 72 hours under fluorescent light when stored in polyvinyl chloride containers at 24 degrees C.
Christen
C
C
Gynecology/Oncology and Adult Acute Pain Service, University of Michigan, Ann Arbor, USA.
Johnson
C E
CE
Walters
J R
JR
D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000737:chemistry*; D000767:Anesthesia, Epidural; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000737:chemistry*; D002045:Bupivacaine / Q000008:administration & dosage / Q000737:chemistry*; D004338:Drug Combinations; D004355:Drug Stability; D004091:Hydromorphone / Q000008:administration & dosage / Q000737:chemistry*; D010147:Pain Measurement
D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D004338:Drug Combinations; D004091:Hydromorphone; D002045:Bupivacaine