title: Spontaneous vascular mineralization in the brain of horses.
abstract: Cerebral vascular mineralization was found in 12 (60%) of 20 3- to 10-year-old healthy horses collected at an abattoir. It was variable in degree and occurred mostly in the pallidal arteries showing two types of lesions; small globoid bodies along capillaries, and amorphous deposits in the wall of arterioles, small- or medium-sized arteries and veins. Both types were strongly positive for periodic acid-Schiff reaction, and weakly positive for von Kossa's and Berlin blue stains. Elemental analysis of the deposit revealed the presence of large amounts of aluminum, moderate amounts of phosphorus, zinc, calcium and iron, and a small amount of sodium.
authors.affiliation: Department of Veterinary Pathology, Faculty of Agriculture, Gifu University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yanai
authors.forename: T
authors.initials: T
authors.lastname: Masegi
authors.forename: K
authors.initials: K
authors.lastname: Ishikawa
authors.forename: H
authors.initials: H
authors.lastname: Sakai
authors.forename: T
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Moritomo
authors.forename: N
authors.initials: N
authors.lastname: Goto
mesh_terms: D000375:Aging; D000818:Animals; D001921:Brain / Q000098:blood supply* / Q000254:growth & development / Q000473:pathology*; D002560:Cerebrovascular Circulation; D005260:Female; D005917:Globus Pallidus / Q000098:blood supply / Q000473:pathology; D006734:Horse Diseases; D006736:Horses / Q000033:anatomy & histology*; D008297:Male; D008659:Metabolic Diseases / Q000473:pathology / Q000662:veterinary*; D009919:Orchiectomy; D014131:Trace Elements / Q000032:analysis*
chemical_list: D014131:Trace Elements