title: [The meningeal sign: a new appraisal].
abstract: OBJECTIVE
  To evaluate the occurrence of the meningeal sign in meningiomas and metastases.
  
  
  METHODS
  We studied 20 patients with meningiomas and 17 patients with cerebral metastases adjacent to the dura. MRI studies (Siemens, Magnetom 1,5) included axial T1-weighted and T2-weighted unenhanced as well as gadolinium-DTPA enhanced T1-weighted (axial, coronal, sagittal) SE imaging. In all patients the tumours were resected with the attached dura mater. Histopathological examinations were done, which corresponded to the area of marked enhancement by gadolinium-DTPA. There was no correlation between the occurrence of the meningeal sign and the histopathological examinations.
  
  
  RESULTS
  In 20 patients with meningiomas adjacent to the dura we found the meningeal sign in 11 cases. Histologically we observed an increase of collagen fibres and fibrocytes. In 5 of 17 cases with superficial cerebral metastases the meningeal sign was seen, histologically as dura infiltrations and microbleedings.
  
  
  CONCLUSIONS
  The meningeal sign is not specific for meningiomas and can be observed in a wide variety of pathological entities.
authors.affiliation: Klinik für Radiologische Diagnostik, Christian-Albrechts-Universität zu Kiel.
authors.forename: A
authors.initials: A
authors.lastname: Hutzelmann
authors.forename: S
authors.initials: S
authors.lastname: Palmié
authors.forename: C
authors.initials: C
authors.lastname: Zimmer
authors.forename: T
authors.initials: T
authors.lastname: Benz
authors.forename: F
authors.initials: F
authors.lastname: Leweke
authors.forename: M
authors.initials: M
authors.lastname: Freund
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary*; D002543:Cerebral Hemorrhage / Q000175:diagnosis; D003287:Contrast Media; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000473:pathology*; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008577:Meningeal Neoplasms / Q000175:diagnosis*; D008579:Meningioma / Q000175:diagnosis*; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
vernacular_title: Das Meningeale Zeichen: eine Neubewertung.