title: Thrombosis of the terminal aorta, deep vein thrombosis, recurrent fetal loss, and antiphospholipid antibodies. Case report.
abstract: The antiphospholipid syndrome (APS) consists clinically of both arterial and venous thrombosis, recurrent fetal loss and thrombocytopenia associated with antiphospholipid antibodies (aPL). Most of these patients were initially found to suffer from systemic lupus erythematosus (SLE). There is an increasing group of patients who exhibit antiphospholipid antibodies and thrombotic complications without clinical features of SLE or related autoimmune disease termed primary antiphospholipid syndrome (PAPS). The case of a 29-year-old woman with thrombosis of the terminal aorta and deep vein thrombosis, recurrent fetal loss, antiphospholipid antibodies and serological support for an underlying connective tissue disease, probably preclinical SLE is reported.
authors.affiliation: Department of Medicine and Dermatology, Hannover Medical School, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Hohlfeld
authors.forename: M
authors.initials: M
authors.lastname: Schneider
authors.forename: R
authors.initials: R
authors.lastname: Hein
authors.forename: M
authors.initials: M
authors.lastname: Barthels
authors.forename: H
authors.initials: H
authors.lastname: von der Lieth
authors.forename: H
authors.initials: H
authors.lastname: Rosenthal
authors.forename: W
authors.initials: W
authors.lastname: Lang
authors.forename: K
authors.initials: K
authors.lastname: Alexander
mesh_terms: D000026:Abortion, Habitual / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D000328:Adult; D000792:Angiography; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D001012:Aorta, Abdominal / Q000473:pathology / Q000601:surgery; D001807:Blood Vessel Prosthesis; D005260:Female; D006801:Humans; D007925:Leriche Syndrome / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D013924:Thrombophlebitis / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D013927:Thrombosis / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D014463:Ultrasonography