title: In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system.
authors.affiliation: Dept. of Metabolism and Pharmacokinetics, Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543-4000, USA.
authors.forename: S
authors.initials: S
authors.lastname: Chong
authors.forename: S A
authors.initials: SA
authors.lastname: Dando
authors.forename: K M
authors.initials: KM
authors.lastname: Soucek
authors.forename: R A
authors.initials: RA
authors.lastname: Morrison
mesh_terms: D000284:Administration, Oral; D018938:Caco-2 Cells; D002352:Carrier Proteins / Q000378:metabolism*; D002463:Cell Membrane Permeability; D004058:Diffusion; D004151:Dipeptides / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology*; D010455:Peptides / Q000493:pharmacokinetics*; D011237:Predictive Value of Tests
chemical_list: D002352:Carrier Proteins; D004151:Dipeptides; D010455:Peptides