title: [Leriche syndrome: treatment with local lysis and subsequent percutaneous transluminal angioplasty].
abstract: Two cases of Leriche's syndrome treated by local thrombolysis and subsequent percutaneous transluminal angioplasty with or without additional stent implantation are described. The fibrinolytic drugs were applied locally into the occlusions through a Mewissen Infusion Catheter and a Katzen Infusion Wire (initial 2.5 mg rt-PA as bolus followed by Urokinase (50000 IU/h) during 24 and 48 hours respectively. Residual stenotic lesions and occlusions were successfully treated with PTA alone in case 1 and with PTA in combination with a stent implantation in case 2. In accordance with Bean et al. (1985) and Goffette et al. (1989) we recommend local lysis in combination with PTA with or without additional stent implantation as an alternative treatment to surgery or systemic lysis for the treatment of Leriche's syndrome.
authors.affiliation: Klinische Abteilung für Angiologie, Universität Wien Osterreich.
authors.forename: R
authors.initials: R
authors.lastname: Katzenschlager
authors.forename: A
authors.initials: A
authors.lastname: Ahmadi
authors.forename: R
authors.initials: R
authors.lastname: Koppensteiner
authors.forename: E
authors.initials: E
authors.lastname: Minar
authors.forename: A
authors.initials: A
authors.lastname: Stümpflen
authors.forename: A
authors.initials: A
authors.lastname: Ugurluoglu
authors.forename: H
authors.initials: H
authors.lastname: Ehringer
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D000800:Angioplasty, Balloon; D001027:Aortography; D003131:Combined Modality Therapy; D006801:Humans; D007925:Leriche Syndrome / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D011994:Recombinant Proteins / Q000008:administration & dosage; D015607:Stents; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Leriche-Syndrom: Behandlung mit lokaler Lyse und anschliessender perkutaner transluminaler Angioplastie.