title: Intussuscepted colonic lipomas: loss of fat attenuation on CT with pathologic correlation in 10 cases.
abstract: BACKGROUND
  To determine if infarction and necrosis is the cause of the confusing soft tissue density on CT within intussuscepting lipomas of the colon.
  
  
  METHODS
  The clinical records, radiologic examinations, and pathologic specimens of all 13 cases of colonic lipomas collected from 1988 to 1994 studied by CT and surgically resected were retrospectively reviewed. Ten of these cases were associated with intussusception; the CT attenuation of the lead point was graded according to its relative fat/soft tissue density. Pathologic specimens were graded independently by a GI pathologist and graded according to the degree of infarction/fat necrosis.
  
  
  RESULTS
  The lipomas ranged from 4 to 7 cm in diameter (mean = 5 cm). Only one case with intussusception, and all three cases without, demonstrated pure fat attenuation on CT and demonstrated pure fat histologically. One case demonstrated soft tissue attenuation and corresponded with the most severely infarcted specimen histologically; two cases with similar but less severe infarction/fat necrosis corresponded with less than 25% fat attenuation. These latter three cases were originally misinterpreted as malignancies rather than lipomas. Six cases maintained greater than 50% fat density and intermediate amounts of infarction/fat necrosis.
  
  
  CONCLUSIONS
  Lipomas may have an atypical appearance when intussuscepted due to varying degrees of infarction/fat necrosis.
authors.affiliation: Department of Radiologic Pathology, Armed Forces Institute of Pathology, Bldg. 54, Room M-121, Alaska and Fern Streets, Washington, DC 20306-6000, USA.
authors.forename: P C
authors.initials: PC
authors.lastname: Buetow
authors.forename: J L
authors.initials: JL
authors.lastname: Buck
authors.forename: N J
authors.initials: NJ
authors.lastname: Carr
authors.forename: L
authors.initials: L
authors.lastname: Pantongrag-Brown
authors.forename: P R
authors.initials: PR
authors.lastname: Ros
authors.forename: D F
authors.initials: DF
authors.lastname: Cruess
mesh_terms: D000328:Adult; D000368:Aged; D003106:Colon / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003108:Colonic Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007443:Intussusception / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008067:Lipoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed