title: Structural allograft in two-stage revisions for failed septic hip arthroplasty.
abstract: We report 11 patients having revision of total hip arthroplasty using massive structural allografts for failure due to sepsis and associated bone loss. All patients had a two-stage reconstruction and the mean follow-up was 47.8 months (24 to 72). Positive cultures were obtained at the first stage in nine of the 11 patients, with Staphylococcus epidermidis being the most common organism. The other two patients had draining sinuses with negative cultures. There was no recurrence of infection in any patient. The mean increase in the modified Harris hip score was 45 and all the grafts appeared to have united to host bone. Two patients required additional procedures, but only one was related to the allograft. Complications included an incomplete sciatic nerve palsy and one case of graft resorption. Our results support the use of massive allografts in failed septic hip arthroplasty in which there is associated bone loss.
authors.affiliation: Mount Sinai Hospital, University of Toronto, Ontario, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Alexeeff
authors.forename: N
authors.initials: N
authors.lastname: Mahomed
authors.forename: E
authors.initials: E
authors.lastname: Morsi
authors.forename: D
authors.initials: D
authors.lastname: Garbuz
authors.forename: A
authors.initials: A
authors.lastname: Gross
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001862:Bone Resorption / Q000601:surgery; D016025:Bone Transplantation; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000601:surgery; D012086:Reoperation; D014184:Transplantation, Homologous; D016896:Treatment Outcome