title: [The evaluation of therapeutic effect on partial splenic embolization (PSE) for liver cirrhosis patients].
abstract: Partial splenic embolization (PSE) was performed on fifty cases with liver cirrhosis underwent no therapy. We evaluated changes of platelet count, ICGR15, GPT and Child-Pugh score which were significantly recovered by PSE. About liver cirrhosis before PSE, K.ICG, GPT, Alb, platelet count and splenic volume were selected as total characteristic factors by principal component analysis. We showed predicting formulas after PSE by multiple regression analysis between five factors selected by principal component analysis and platelet count, HPT, PT, Alb, ICGR15, K.ICG, GOT, GPT and Child-Pugh score after PSE. In conclusion, it is suggested that PSE is useful for recovering of platelet count and liver function. We made it possible to estimate therapeutic effect by predicting formulas before PSE.
authors.affiliation: First Department of Surgery, Nippon Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nishikubo
authors.forename: M
authors.initials: M
authors.lastname: Onda
authors.forename: T
authors.initials: T
authors.lastname: Tajiri
authors.forename: D Y
authors.initials: DY
authors.lastname: Kim
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004621:Embolization, Therapeutic / Q000379:methods; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood / Q000628:therapy*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010976:Platelet Count; D011379:Prognosis; D012044:Regression Analysis; D013157:Splenic Artery