title: [Adverse effects on the respiratory system in textile printing sprayers].
abstract: OBJECTIVE
  To study the initial respiratory effects and those observed 18 months later after the inhalation of toxic and irritant substances in textile aerography workers.
  
  
  METHODS
  Seventeen patients (14 women and 3 men), with a mean age of 21 years (range: 18-38).
  
  
  METHODS
  Initially, pulmonary effects were assessed by pathological (transbronchial biopsy and/or video-thoracoscopy) and functional findings [spirometry with lung volumes and study of diffusion capacity of CO (DLCO)]. Eighteen months later a challenge bronchial test with histamine was performed.
  
  
  RESULTS
  Forty-one per cent of patients had pathologic lesions with intraalveolar fibrin, 35% had minimal non-specific lesions, 18% bronchiolitis obliterans with organized pneumonia (BOOP) and 6% pulmonary fibrosis and BOOP. Functional respiratory test showed two patients with a slight restrictive pattern, one patient with very severe restriction and six patients with low DLCO. The challenge tests was positive for 59% of patients.
  
  
  CONCLUSIONS
  After the massive inhalation of irritant and/or toxic substances, patients presented different types of pathological response at pulmonary level. In our workers histological repairing lesions--of high or low degree--were found, BOOP being the lesions observed most frequently, and different patterns of functional involvement. Fifty-nine per cent of cases developed non-specific bronchial hyperreactivity consistent with a reactive airways dysfunction syndrome.
authors.affiliation: Servicio de Neumología, Hospital Universitario La Fe, Valencia.
authors.forename: A
authors.initials: A
authors.lastname: Solé Jover
authors.forename: M E
authors.initials: ME
authors.lastname: b1rtínez Francés
authors.forename: P J
authors.initials: PJ
authors.lastname: Cordero Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Vallterra Musoles
authors.forename: V
authors.initials: V
authors.lastname: Macián Gisbert
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D016535:Bronchial Hyperreactivity / Q000175:diagnosis; D018549:Cryptogenic Organizing Pneumonia / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D010150:Paint / Q000009:adverse effects*; D011658:Pulmonary Fibrosis / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D012129:Respiratory Function Tests; D012997:Solvents / Q000009:adverse effects*; D013577:Syndrome; D013783:Textile Industry
chemical_list: D012997:Solvents
vernacular_title: Efectos adversos sobre el tracto respiratorio en trabajadores de aerografía textil.