title: [Fine needle aspiration biopsy of thyroid nodules. Analysis of results obtained using a new method with histological examination of the sample].
abstract: Fine needle aspiration biopsy (FNAB) is the most useful preoperative work up method for patients with nodular goiter. We analyze 173 patients that underwent FNAB and were subsequently operated. The sample with FNAB was processed both for cytological and histological study, using methods developed at the hospital. The preoperative diagnosis reached was compared with that obtained with the surgical piece. Results showed that the histological analysis of the FNAB sample improved the sensitivity of the method, when compared with the cytological study, from 68.5% to 87.8% (p < 0.035) without modifying specificity (100% for both methods). It is concluded that FNAB with histological study of the sample has a high diagnostic yield and is exempt of complications.
authors.affiliation: Departamento de Endocrinología, Facultad de Medicina, Universidad de Chile, (Campus Occidente), Hospital San Juan de Dios, Santiago de Chile.
authors.forename: M
authors.initials: M
authors.lastname: Domínguez
authors.forename: C
authors.initials: C
authors.lastname: Franco
authors.forename: L
authors.initials: L
authors.lastname: Contreras
authors.forename: J
authors.initials: J
authors.lastname: Torres
authors.forename: R
authors.initials: R
authors.lastname: Volpato
authors.forename: F
authors.initials: F
authors.lastname: Cerpa
authors.forename: G
authors.initials: G
authors.lastname: Pérez
authors.forename: V
authors.initials: V
authors.lastname: Martínez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods*; D018276:Carcinoma, Medullary / Q000473:pathology; D002291:Carcinoma, Papillary / Q000473:pathology; D005260:Female; D006044:Goiter, Nodular / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011300:Preoperative Care; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000473:pathology; D016606:Thyroid Nodule / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014463:Ultrasonography
vernacular_title: Punción de nódulos tiroídeos con aguja fina. Análisis de los resultados obtenidos utilizando una nueva metódica con examen histológico de la muestra.