[Adverse effects on the respiratory system in textile printing sprayers].
OBJECTIVE
To study the initial respiratory effects and those observed 18 months later after the inhalation of toxic and irritant substances in textile aerography workers.


METHODS
Seventeen patients (14 women and 3 men), with a mean age of 21 years (range: 18-38).


METHODS
Initially, pulmonary effects were assessed by pathological (transbronchial biopsy and/or video-thoracoscopy) and functional findings [spirometry with lung volumes and study of diffusion capacity of CO (DLCO)]. Eighteen months later a challenge bronchial test with histamine was performed.


RESULTS
Forty-one per cent of patients had pathologic lesions with intraalveolar fibrin, 35% had minimal non-specific lesions, 18% bronchiolitis obliterans with organized pneumonia (BOOP) and 6% pulmonary fibrosis and BOOP. Functional respiratory test showed two patients with a slight restrictive pattern, one patient with very severe restriction and six patients with low DLCO. The challenge tests was positive for 59% of patients.


CONCLUSIONS
After the massive inhalation of irritant and/or toxic substances, patients presented different types of pathological response at pulmonary level. In our workers histological repairing lesions--of high or low degree--were found, BOOP being the lesions observed most frequently, and different patterns of functional involvement. Fifty-nine per cent of cases developed non-specific bronchial hyperreactivity consistent with a reactive airways dysfunction syndrome.
Solé Jover
A
A
Servicio de Neumología, Hospital Universitario La Fe, Valencia.
b1rtínez Francés
M E
ME
Cordero Rodríguez
P J
PJ
Vallterra Musoles
J
J
Macián Gisbert
V
V
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D016535:Bronchial Hyperreactivity / Q000175:diagnosis; D018549:Cryptogenic Organizing Pneumonia / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D010150:Paint / Q000009:adverse effects*; D011658:Pulmonary Fibrosis / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D012129:Respiratory Function Tests; D012997:Solvents / Q000009:adverse effects*; D013577:Syndrome; D013783:Textile Industry
D012997:Solvents
Efectos adversos sobre el tracto respiratorio en trabajadores de aerografía textil.