Peripheral blood gamma delta T cells in human listeriosis.
A phenotypical analysis carried out by direct immunofluorescence and two-colour cytofluorometry showed that the number of lymphocytes bearing the gamma delta T-cell receptor heterodimer was increased in the blood of eight children with Listeria monocytogenes infection, mainly due to an expansion of cells identified by monoclonal antibodies which recognize V delta 2 gene products. These findings are further evidence that gamma delta T cells are in some way involved in the immune response directed against human intracellular pathogens.
Bertotto
A
A
Department of Paediatrics, Perugia University Medical School, Italy.
Spinozzi
F
F
Gerli
R
R
Bassotti
G
G
Forenza
N
N
Vagliasindi
C
C
Vaccaro
R
R
D005260:Female; D006801:Humans; D016130:Immunophenotyping; D007223:Infant; D007231:Infant, Newborn; D008089:Listeria monocytogenes / Q000276:immunology*; D018655:Lymphocyte Count; D008297:Male; D008584:Meningitis, Listeria / Q000175:diagnosis / Q000276:immunology*; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000032:analysis*
D016692:Receptors, Antigen, T-Cell, gamma-delta