3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.
Kulagowski
J J
JJ
Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow, Essex, U.K.
Broughton
H B
HB
Curtis
N R
NR
Mawer
I M
IM
Ridgill
M P
MP
Baker
R
R
Emms
F
F
Freedman
S B
SB
Marwood
R
R
Patel
S
S
Patel
S
S
Ragan
C I
CI
Leeson
P D
PD
D000818:Animals; D002460:Cell Line; D018492:Dopamine Antagonists / Q000737:chemistry / Q000494:pharmacology*; D065127:Dopamine D2 Receptor Antagonists; D006801:Humans; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D011758:Pyrroles / Q000737:chemistry / Q000494:pharmacology*; D050638:Receptors, Dopamine D4
C099630:3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine; C493599:DRD4 protein, human; D018492:Dopamine Antagonists; D065127:Dopamine D2 Receptor Antagonists; D011725:Pyridines; D011758:Pyrroles; D050638:Receptors, Dopamine D4