[Diabetic mastopathy with epithelioid fibroblasts :differential diagnosis from an infiltrating lobular carcinoma of the breast. Report of two cases].
Two cases of diabetic mastopathy are reported. The patients presented with a rapidly increasing mammary mass. The pathologic findings of diabetic mastopathy usually consist of a lymphocytic lobulitis, a dense stromal fibrosis and prominent epithelioid fibroblasts. In our two cases, the latter findings were initially misinterpreted as malignant cells of an invasive lobular carcinoma. These lesions were first described in longstanding insulin dependent diabetics but recent reports showed that they could also occur in patients with other auto-immune disorders (systemic lupus erythematous, hypothyroidism). Diabetic mastopathy may reoccur locally and the treatment remains to be determined.
Tanière
P
P
Laboratoire central d'Anatomie Pathologique, Hôpital Edouard Herriot, Lyon.
Poulard
G
G
Frappart
L
L
Berger
G
G
Goncalves
M
M
Vauzelle
J L
JL
Delecluse
D J
DJ
Bailly
C
C
Boucheron
S
S
Berger
F
F
D000328:Adult; D001943:Breast Neoplasms / Q000150:complications / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000473:pathology*; D018275:Carcinoma, Lobular / Q000150:complications / Q000473:pathology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D006801:Humans
Mastopathie diabétique avec fibroblastes épithélioïdes: piège diagnostique avec un carcinome lobulaire infiltrant du sein. A propos de deux cas.