title: Antibody-directed enzyme prodrug therapy (ADEPT) for treatment of major solid tumour disease.
authors.affiliation: Cancer Research Department, Zeneca Pharmaceuticals, Macclesfield, Cheshire, U.K.
authors.forename: D C
authors.initials: DC
authors.lastname: Blakey
authors.forename: P J
authors.initials: PJ
authors.lastname: Burke
authors.forename: D H
authors.initials: DH
authors.lastname: Davies
authors.forename: R I
authors.initials: RI
authors.lastname: Dowell
authors.forename: R G
authors.initials: RG
authors.lastname: Melton
authors.forename: C J
authors.initials: CJ
authors.lastname: Springer
authors.forename: A F
authors.initials: AF
authors.lastname: Wright
mesh_terms: D000818:Animals; D057487:Enzyme Therapy; D004798:Enzymes / Q000008:administration & dosage; D006801:Humans; D018796:Immunoconjugates / Q000008:administration & dosage / Q000627:therapeutic use*; D009150:Mustard Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000628:therapy*; D011355:Prodrugs / Q000008:administration & dosage / Q000627:therapeutic use*; D014183:Transplantation, Heterologous
chemical_list: D004798:Enzymes; D018796:Immunoconjugates; D009150:Mustard Compounds; D011355:Prodrugs