title: Different heat-shock proteins are constitutively overexpressed in cadmium and pentachlorophenol adapted Euglena gracilis cells.
abstract: To determine whether cellular resistance to a given stressor is related to induction of specific stress-proteins, responses of two adapted Euglena gracilis cell lines, one adapted to cadmium, the other adapted to pentachlorophenol, were analyzed. Our experiments showed that two sets of heat-shock proteins (hsps) were constitutively overexpressed in each cell line: while hsp90, hsp70, hsp55, and hsp40 were induced in cadmium-resistant cells, only hsp40 was induced in pentachlorophenol-adapted cells.
authors.affiliation: Laboratoire Métabolisme Cellulaire et Xénobiotiques, Faculté de Pharmacie, Châtenay-Malabry, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Barque
authors.forename: A
authors.initials: A
authors.lastname: Abahamid
authors.forename: H
authors.initials: H
authors.lastname: Chacun
authors.forename: J
authors.initials: J
authors.lastname: Bonaly
mesh_terms: D000818:Animals; D002104:Cadmium / Q000494:pharmacology*; D004351:Drug Resistance; D015180:Electrophoresis, Gel, Two-Dimensional; D004591:Electrophoresis, Polyacrylamide Gel; D005056:Euglena gracilis / Q000187:drug effects / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant / Q000187:drug effects; D018840:HSP70 Heat-Shock Proteins / Q000096:biosynthesis; D018841:HSP90 Heat-Shock Proteins / Q000096:biosynthesis; D006360:Heat-Shock Proteins / Q000096:biosynthesis* / Q000302:isolation & purification; D008970:Molecular Weight; D010416:Pentachlorophenol / Q000494:pharmacology*
chemical_list: D018840:HSP70 Heat-Shock Proteins; D018841:HSP90 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D002104:Cadmium; D010416:Pentachlorophenol