[Test for the effects of mutagenic toxic fungal metabolites originating from municipal landfill sites].
The purpose of the study is to assess the mutagenic effect of mycotoxins produced by moulds growing on municipal landfill sites. Mutagenicity of toxic fungal metabolites was determined by the Salmonella plate incorporation assay with two strains of bacteria: TA98 and TA100, with and without metabolic activation. The results obtained indicate that there is a severe hazard caused by these mycotoxins detected main by TA98 with metabolic activation. The most mutagenic mixture of mycotoxins acting directly on both strains was produced by Aspergillus nidulans. The highest mutagenic effect detected by TA98 with metabolic activation was found in the mixture of mycotoxins produced by one of three isolated Aspergillus fumigatus varieties.
Bubak
A
A
Pracowni Mutagenezy Srodowiskowej, Instytutu Medycyny Pracy i Zdrowia Srodowiskowego w Sosnowcu.
Mielzyńska
D
D
Siwińska
E
E
Ulfig
K
K
D001230:Aspergillus / Q000378:metabolism*; D004784:Environmental Monitoring; D015386:Hazardous Substances / Q000032:analysis; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis*; D009183:Mycotoxins / Q000096:biosynthesis*; D012037:Refuse Disposal; D013045:Species Specificity
D015386:Hazardous Substances; D009153:Mutagens; D009183:Mycotoxins
Badanie efektu mutagennego metabolitów grzybów toksynotwórczych pochodzacych z wysypiska odpadów komunalnych.