[Relevance of heparin-induced type II thrombocytopenia in surgery: report of 3 cases].
Heparin-induced thrombocytopenia (HIT) is a frequent type of drug induced thrombocytopenia. The clinically benign type I has to be distinguished from the life threatening type II due to the risk of thromboembolic complications. Three cases of type II HIT with acute thrombosis of the pelvic and lower extremity arteries and successful surgical treatment are reported. The majority of cases of an imminent type II HIT can be recognized in time by monitoring platelet count. The laboratory tests relevant to diagnosis are discussed. An immediate stop of the heparin therapy represents the causal treatment of type II HIT. As an alternative, anticoagulants may be used.
Manouguian
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Sektion Gefässchirurgie, Krankenhaus Bethanien, Moers.
D000368:Aged; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007511:Ischemia / Q000097:blood / Q000139:chemically induced / Q000601:surgery; D007866:Leg / Q000098:blood supply; D008875:Middle Aged; D010976:Platelet Count / Q000187:drug effects; D011183:Postoperative Complications / Q000097:blood / Q000139:chemically induced* / Q000601:surgery; D012086:Reoperation; D013921:Thrombocytopenia / Q000097:blood / Q000139:chemically induced* / Q000601:surgery; D013923:Thromboembolism / Q000097:blood / Q000139:chemically induced* / Q000601:surgery
D006493:Heparin
Die Relevanz der heparininduzierten Thrombozytopenie (HIT) Typ II in der Chirurgie: Bericht über 3 Fälle.