Weekly versus daily oral iron administration: are we asking the right questions?
The separation of oral iron doses to conform to cycle of intestinal mucosa turnover has been suggested by some as a method to improve the efficiency of uptake for therapeutic doses of iron. A short-term study in healthy American women failed to confirm a superior absorption of radioiron with a 7-day interval versus everyday administration of a 50-mg iron dose, but the iron status of the experimental subjects may have produced an inappropriate population on which to test a question relevant to Third World populations.
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Center for Studies of Sensory Impairment, Aging and Metabolism, Guatemala City, Guatemala.
D000284:Administration, Oral; D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000188:drug therapy / Q000453:epidemiology / Q000378:metabolism; D002986:Clinical Trials as Topic; D003906:Developing Countries; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D007501:Iron / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D007615:Kansas / Q000453:epidemiology; D008297:Male
D007501:Iron