title: Colorectal polyp detection with CT colography: two- versus three-dimensional techniques. Work in progress.
abstract: OBJECTIVE
  To compare detection of colorectal polyps with two-dimensional (2D) computed tomographic (CT) colography only, three-dimensional (3D) CT colography only, and a combination of 2D and 3D CT colography.
  
  
  METHODS
  A total of 11 computer-simulated polyps (1-10 mm) were placed randomly in five identical CT data sets for images of a 72-year-old man's polyp-free, rectosigmoid colon. Fifteen CT colographic data sets were produced: five with 2D CT images only, five with 3D CT images only, and five with 2D and 3D CT images. Two radiologists randomly, blindly, and independently evaluated all 15 data sets to detect the simulated polyps.
  
  
  RESULTS
  No polyps 2 mm or smaller were detected. No statistically significant differences in the detection of colorectal polyps were found between the three techniques. However, the combination of 2D and 3D CT colography resulted in polyp detection rates that were greater than or equal to those of 2D or 3D CT colography alone. Flat polyps were more difficult to detect than sessile polyps. Five false-positive findings occurred with 2D CT colography.
  
  
  CONCLUSIONS
  A combined display of 2D and 3D CT images likely provides the greatest rate of detection of colorectal polyps.
authors.affiliation: Department of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: A K
authors.initials: AK
authors.lastname: Hara
authors.forename: C D
authors.initials: CD
authors.lastname: Johnson
authors.forename: J E
authors.initials: JE
authors.lastname: Reed
authors.forename: R L
authors.initials: RL
authors.lastname: Ehman
authors.forename: D M
authors.initials: DM
authors.lastname: Ilstrup
mesh_terms: D000368:Aged; D003106:Colon / Q000000981:diagnostic imaging; D003111:Colonic Polyps / Q000000981:diagnostic imaging; D003113:Colonoscopy; D003198:Computer Simulation; D016001:Confidence Intervals; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007417:Intestinal Polyps / Q000000981:diagnostic imaging*; D008297:Male; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*