Vaccines in the prevention of viral pneumonia.
Vaccines to control respiratory virus infections have been limited to inactivated whole virus or split virus product of influenza. Over the last few years, advances in the understanding of immunity to and importance of these infections has led to the development of newer, more immunogenic inactivated influenza vaccines and to the exploration of live attenuated influenza vaccines. In parallel, both inactivated and live attenuated vaccines against respiratory syncytial virus and parainfluenza virus have been undergoing evaluation. More effective or new vaccines could reduce morbidity, reduce the frequency of hospitalization, and decrease the death rate. Since viral respiratory disease would be decreased in frequency, vaccines could reduce the use of antibiotics, and by so doing, preserve the usefulness of our currently available antibiotics.
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Department of Internal Medicine, University of Rochester School of Medicine and Dentistry, NY 14642, USA.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007252:Influenza Vaccines / Q000627:therapeutic use; D007251:Influenza, Human / Q000235:genetics / Q000276:immunology / Q000517:prevention & control; D008875:Middle Aged; D018184:Paramyxoviridae Infections / Q000276:immunology / Q000517:prevention & control; D010850:Picornaviridae Infections / Q000276:immunology / Q000517:prevention & control; D011024:Pneumonia, Viral / Q000276:immunology / Q000517:prevention & control*; D018357:Respiratory Syncytial Virus Infections / Q000276:immunology / Q000517:prevention & control; D014611:Vaccination / Q000379:methods; D014613:Vaccines, Attenuated / Q000235:genetics / Q000276:immunology / Q000592:standards; D015164:Vaccines, Inactivated / Q000235:genetics / Q000276:immunology / Q000592:standards; D014614:Vaccines, Synthetic / Q000737:chemistry / Q000235:genetics / Q000276:immunology / Q000592:standards
D007252:Influenza Vaccines; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated; D014614:Vaccines, Synthetic