An iterative approach to the solution of the inverse problem.
The bioelectric inverse problem is framed as a search through a feasible set of solutions for one that is physiologically plausible. The definition of the feasible set of solutions takes into account the important effects of measurement noise. This leads to an iterative approach. At each step, a regularized inverse is used to limit the amount of brain that need be searched in the next step. The approach is tested in a model system that incorporates a digitized cadaver cortex into a 3-shell spherical replica of the head.
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Department of Ophthalmology, University of Texas, Southwestern Medical School, Dallas 75235, USA. dick@striate.swmed.edu
D016477:Artifacts; D001931:Brain Mapping; D004569:Electroencephalography; D006801:Humans; D008433:Mathematics; D008959:Models, Neurological; D011340:Problem Solving / Q000502:physiology*