title: Factors associated with healing leg ulceration with high compression.
abstract: To investigate factors relevant to the healing of leg ulceration by high compression, patients were interviewed using a standard questionnaire prior to treatment with a four-layer bandage high-compression system in six community ulcer clinics. We explored the relation of size, ulcer duration and medical history to healing. Cumulative healing rates were high using this method, being 69% after 12 weeks and 83% after 24 weeks. Twelve-week healing rates varied slightly between clinics, ranging from 62% to 83%. Univariate analysis of the total group showed that male sex (RR = 0.77, p = 0.023), poor limb joint mobility (RR = 0.39, p < 0.001), poor general mobility (RR = 0.49, p = 0.015), treatment at home (RR = 0.52, p < 0.001), ulcer size > 10 cm2 (RR = 0.37, p < 0.001), history of deep vein thrombosis (RR = 0.67, p = 0.016) and ulcer duration >6 months (RR = 0.35, p < 0.001) were significantly inversely associated with healing, Ulcer size, duration, limb joint mobility and general mobility were significant independent factors in multivariate analysis.
authors.affiliation: Department of Surgery, Charing Cross Hospital, London.
authors.forename: P J
authors.initials: PJ
authors.lastname: Franks
authors.forename: C J
authors.initials: CJ
authors.lastname: Moffatt
authors.forename: M
authors.initials: M
authors.lastname: Connolly
authors.forename: N
authors.initials: N
authors.lastname: Bosanquet
authors.forename: M I
authors.initials: MI
authors.lastname: Oldroyd
authors.forename: R M
authors.initials: RM
authors.lastname: Greenhalgh
authors.forename: C N
authors.initials: CN
authors.lastname: McCollum
mesh_terms: D000328:Adult; D000368:Aged; D001458:Bandages; D003151:Community Health Centers; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007871:Leg Ulcer / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D012307:Risk Factors; D011795:Surveys and Questionnaires; D016896:Treatment Outcome