title: Keratoacanthoma in Japanese Hawaiians in Kauai, Hawaii.
abstract: BACKGROUND
  This is the first incidence report of keratoacanthoma (KA) in a Japanese ethnic population.
  
  
  METHODS
  The study was designed as a 5-year prospective incidence study using an island-wide survey of Japanese residents in Kauai, Hawaii, during the years 1983 through 1987.
  
  
  RESULTS
  Eleven Japanese residents of Kauai, three men and eight women, had KA. The crude incidence is 22.1 per 100,000 Japanese Kauaiian population. Two thirds of the lesions were on the extremities. No recurrence was noted, but a nonmelanoma skin cancer developed in some patients.
  
  
  CONCLUSIONS
  The incidence of KA in a Japanese ethnic population is not low. Ultraviolet light exposure must, in part, contribute to the development of KA. This is supported by fact that the incidence of KA in Japanese residents in Kauai is much higher than in Japan and that most of the KAS appear on exposed skin.
authors.affiliation: Department of Medicine, University of Wisconsin School of Medicine, Madison, USA.
authors.forename: G T
authors.initials: GT
authors.lastname: Reizner
authors.forename: T Y
authors.initials: TY
authors.lastname: Chuang
authors.forename: D J
authors.initials: DJ
authors.lastname: Elpern
authors.forename: J L
authors.initials: JL
authors.lastname: Stone
authors.forename: E R
authors.initials: ER
authors.lastname: Farmer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006254:Hawaii / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007564:Japan / Q000208:ethnology; D007636:Keratoacanthoma / Q000453:epidemiology / Q000208:ethnology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies