title: Mitral valve replacement for severe mitral regurgitation in infants with anomalous left coronary artery from the pulmonary artery.
abstract: Infants with anomalous left coronary artery from the pulmonary artery (ALCAPA) may present with heart failure, mitral regurgitation, and dilated cardiomyopathy. Reestablishment of a two coronary artery system markedly improves the morbidity and mortality. However, the mitral regurgitation may continue to deteriorate despite surgical correction of the ALCAPA because of previous ischemic damage to the papillary muscles and chordae. Surgical intervention, including mitral valve replacement, may be required even during infancy. We present two infants with ALCAPA who required early mitral valve replacement for severe mitral regurgitation and have done well subsequently.
authors.affiliation: Department of Cardiology, Royal Children's Hospital, Parkville, Victoria, Australia.
authors.forename: M C
authors.initials: MC
authors.lastname: Yam
authors.forename: S
authors.initials: S
authors.lastname: Menahem
mesh_terms: D003330:Coronary Vessel Anomalies / Q000150:complications* / Q000000981:diagnostic imaging; D004452:Echocardiography; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D007223:Infant; D008297:Male; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D011651:Pulmonary Artery / Q000002:abnormalities* / Q000000981:diagnostic imaging