title: Translocation t(8;22) and monosomy 7 in a case of acute lymphoblastic leukemia expressing myeloid markers.
abstract: The simultaneous coexpression of lymphoid and myeloid markers has been observed in some cases of childhood acute lymphoblastic leukemias (ALL). In this paper, we describe a 6-year-old male patient with an ALL expressing myeloid antigens in whom a novel karyotypic association, t(8;22) and monosomy 7, and high Ag-NOR activity were found concomitantly with a very short survival.
authors.affiliation: Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Buenos Aires, Argentina.
authors.forename: E
authors.initials: E
authors.lastname: Pedrazzini
authors.forename: S C
authors.initials: SC
authors.lastname: Goldztein
authors.forename: G
authors.initials: G
authors.lastname: Shilton
authors.forename: I
authors.initials: I
authors.lastname: Slavutsky
mesh_terms: D014408:Biomarkers, Tumor; D002648:Child; D002892:Chromosomes, Human, Pair 22; D002897:Chromosomes, Human, Pair 7; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D008297:Male; D009006:Monosomy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D014178:Translocation, Genetic
chemical_list: D014408:Biomarkers, Tumor