A circadian perspective on myocardial ischaemia.
The non-uniform occurrence of myocardial ischaemia, with a trough at night and a peak in the morning, is at the base of the concept of a circadian distribution of coronary events. Cardiovascular variables known to influence the occurrence of ischaemia have similar rhythms, and a likely culprit could be hidden among them. Nevertheless, in many cases an identifiable trigger is lacking and the prediction of ischaemia is still elusive.
Gnecchi-Ruscone
T
T
Servizio di Cardiologia, Ospedale S.L.Mandic, Merate, Italy.
Montano
N
N
Guzzetti
S
S
Pagani
M
M
D001341:Autonomic Nervous System / Q000503:physiopathology; D017704:Baroreflex / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology*; D006801:Humans; D017202:Myocardial Ischemia / Q000503:physiopathology*; D014666:Vasomotor System / Q000503:physiopathology