-Glucose, insulin and C-peptide kinetics during tocolysis with oral fenoterol-.
OBJECTIVE
The effect of oral fenoterol therapy (40 mg/day) on the kinetics of glucose, insulin and C-peptide during an oral glucose tolerance test (oGTT; 100 g glucose) was investigated in the third trimester.


METHODS
54 patients without tocolytic therapy (25 with a pathologic oGTT) were compared with 36 patients who received tocolytic therapy (18 patients with a pathologic oGTT).


RESULTS
The patients with a normal or pathologic oGTT and with or without tocolytic therapy showed no significant differences in respect of the concentrations of glucose, insulin and C-peptide. During tocolytic therapy, an early increase in insulin was observed as well as slightly elevated C-peptide concentrations and a decreased C-peptide/insulin quotient.
Günter
H H
HH
Zentrum Frauenheilkunde, Medizinischen Hochschule Hannover, Deutschland.
Nitschmann
A
A
Balks
H J
HJ
Wedeking-Schöhl
H
H
Niesert
S
S
D000284:Administration, Oral; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D002096:C-Peptide / Q000097:blood*; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage* / Q000009:adverse effects; D005951:Glucose Tolerance Test; D006801:Humans; D007231:Infant, Newborn; D007328:Insulin / Q000097:blood*; D007752:Obstetric Labor, Premature / Q000097:blood / Q000517:prevention & control*; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood / Q000139:chemically induced; D015145:Tocolysis; D015149:Tocolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects
D001786:Blood Glucose; D002096:C-Peptide; D007328:Insulin; D015149:Tocolytic Agents; D005280:Fenoterol
Glukose-, Insulin- und C-Peptid-Kinetik unter Tokolyse mit oralem Fenoterol.