Cyclosporine and tacrolimus both suppress activation of Kupffer cells in vitro.
Tojimbara
T
T
Department of Surgery, Stanford University Medical Center, California, USA.
Bermudez
L E
LE
Egawa
H
H
Hayashi
M
M
So
S K
SK
Esquivel
C O
CO
D000818:Animals; D002478:Cells, Cultured; D016572:Cyclosporine / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007728:Kupffer Cells / Q000187:drug effects / Q000276:immunology*; D008262:Macrophage Activation / Q000187:drug effects*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013481:Superoxides / Q000378:metabolism*; D016559:Tacrolimus / Q000494:pharmacology*; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis; D015054:Zymosan / Q000494:pharmacology
D007166:Immunosuppressive Agents; D014409:Tumor Necrosis Factor-alpha; D013481:Superoxides; D016572:Cyclosporine; D015054:Zymosan; D016559:Tacrolimus