title: Gastric carcinoma in siblings with Friedreich's ataxia.
abstract: Friedreich's ataxia is a hereditary neurological condition characterized by severe ataxia. We report the cases of two siblings with this condition, both of whom developed signet ring cell adenocarcinoma of the stomach at a young age. This association has not been previously described and it suggests the presence of an unidentified aberrant gene.
authors.affiliation: Department of Surgery, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: R
authors.initials: R
authors.lastname: Ackroyd
authors.forename: A J
authors.initials: AJ
authors.lastname: Shorthouse
authors.forename: T J
authors.initials: TJ
authors.lastname: Stephenson
mesh_terms: D000328:Adult; D018279:Carcinoma, Signet Ring Cell / Q000150:complications* / Q000473:pathology; D005260:Female; D005621:Friedreich Ataxia / Q000150:complications* / Q000235:genetics; D006801:Humans; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology