Lyme neuroborreliosis disguised as normal pressure hydrocephalus.
A 74-year-old woman presented with gait impairment, urinary incontinence, and dementia. She showed lymphocytic CSF pleocytosis and pronounced intrathecal Borrelia burgdorferi antibody production, indicating active Lyme neuroborreliosis. The syndrome of normal-pressure hydrocephalus (NPH) fully remitted after ceftriaxone treatment. Lyme neuroborreliosis may cause NPH by interfering with subarachnoid CSF flow.
Danek
A
A
Department of Neurology, Ludwig-Maximilians-Universität, Klinikum Grosshadern, Munich, Germany.
Uttner
I
I
Yoursry
T
T
Pfister
H W
HW
D000368:Aged; D001259:Ataxia / Q000209:etiology; D002443:Ceftriaxone / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000166:cytology; D003704:Dementia / Q000209:etiology; D005260:Female; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D007958:Leukocyte Count; D008193:Lyme Disease / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D012212:Rheology; D014549:Urinary Incontinence / Q000209:etiology
D002443:Ceftriaxone