title: [Circulatory support by an electrically stimulated muscle flap. Experimental experiences].
abstract: Functional electrical stimulation of the latissimus dorsi muscle flap for circulatory assistance extends the traditional concept of using this flap for reconstructive procedures into the field of cardiac surgery. It requires a transformed muscle which is able to contract for long periods of time without fatigue. Two main groups of experiments have been carried out in sheep. In six sheep the latissimus dorsi muscle (MLD) was transformed into a fatigue-resistant muscle by the means of multichannel stimulation of the supplying motor nerve. After that, stimulation of MLD at a frequency of 70 contractions per minute could be performed continuously without significant muscle fatigue. The loss of maximal force caused by the conditioning procedure was about one third of the initial force. In a second series of acute experiments the MLD was used for cardiomyoplasty. The muscle was divided into two parts which were wrapped around the heart in two different forms. The resting tension of the muscle was preserved. EKG-synchronous stimulation resulted in an increase in left ventricular pressure between 12 and 53%. The increase in arterial pressure was between 10,6 and 58%.
authors.affiliation: Universitätsklinik für Chirurgie, Abteilung Wiederherstellende und Plastische Chirurgie, Universität Wien, Osterreich.
authors.forename: W
authors.initials: W
authors.lastname: Girsch
authors.forename: R
authors.initials: R
authors.lastname: Koller
authors.forename: H
authors.initials: H
authors.lastname: Lanmüller
authors.forename: R
authors.initials: R
authors.lastname: Seitelberger
authors.forename: M
authors.initials: M
authors.lastname: Rab
authors.forename: L
authors.initials: L
authors.lastname: Huber
authors.forename: H
authors.initials: H
authors.lastname: Schima
authors.forename: H G
authors.initials: HG
authors.lastname: Stöhr
authors.forename: U M
authors.initials: UM
authors.lastname: Losert
authors.forename: E
authors.initials: E
authors.lastname: Wolner
mesh_terms: D000818:Animals; D002302:Cardiac Output / Q000502:physiology*; D018421:Cardiomyoplasty / Q000295:instrumentation* / Q000379:methods; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004562:Electrocardiography / Q000295:instrumentation; D004567:Electrodes, Implanted; D004867:Equipment Design; D009046:Motor Neurons / Q000502:physiology; D018763:Muscle Fatigue / Q000502:physiology; D009200:Myocardial Contraction / Q000502:physiology*; D012756:Sheep
vernacular_title: Kreislaufunterstützung durch elektrisch stimulierte Muskellappen. Experimentelle Erfahrungen.