title: [Purgative activity of Cassia italica].
abstract: Twenty guinea pigs were used to study the effects of Cassia italica leaves and pods extracts on intestinal motricity in vitro. The results obtained showed that the plant stimulate intestinal contractions with dose-dependent relation. Moreover, Cassia italica contractile activity was comparable to the acetylcholine one and was inhibited by atropine. According to these results, Cassia italica purgative activity is supported at least, by it's stimulating effect on intestinal motricity.
authors.affiliation: Département de Physiologie, Pharmacodynamie et Thérapeutique, Ecole Inter-Etats des Sciences et Médecine Vétérinaires (E.I.S.M.V.), Dakar, Sénégal.
authors.forename: M
authors.initials: M
authors.lastname: Assane
authors.forename: R
authors.initials: R
authors.lastname: Nydyema
authors.forename: E
authors.initials: E
authors.lastname: Bassene
authors.forename: A
authors.initials: A
authors.lastname: Sere
authors.forename: O
authors.initials: O
authors.lastname: Gaye
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002366:Cassia; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006168:Guinea Pigs; D009119:Muscle Contraction / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal
chemical_list: D010936:Plant Extracts; D001285:Atropine; D000109:Acetylcholine
vernacular_title: Contribution à l'étude de l'activité purgative de Cassia italica.