title: Imaging of biliary complications following paediatric liver transplantation.
abstract: Biliary complications (BC) are well recognised following paediatric liver transplantation. We reviewed retrospectively 169 consecutive liver transplants performed in 139 children. BC occurred in 36/169 grafts (21 %) in 35/139 patients (25 %). Biliary obstruction was present in 18/169 grafts (11 %), biliary leakage in 14/169 grafts (8 %) and a combination of obstruction and leakage was present in 4/169 (2 %) grafts. BC were as likely to present radiologically as they were with either clinical and/or biochemical abnormalities. Most BC (26/36, i. e. 72 %) occurred in the first 2 weeks following transplantation. Ultrasound and cholangiography were the principle imaging modalities used for detection of these complications. False negative ultrasound examinations occurred in three patients with biliary obstruction and in three patients with biliary leakage. False negative cholangiograms occurred in two patients with biliary leakage. Ultrasound is important in the post-operative surveillance of paediatric liver transplants, with cholangiography having a complementary role in those with BC.
authors.affiliation: Department of Radiology, Birmingham Children's Hospital NHS Trust, Ladywood Middleway, Birmingham B16 8ET, UK.
authors.forename: J F
authors.initials: JF
authors.lastname: Griffith
authors.forename: P R
authors.initials: PR
authors.lastname: John
mesh_terms: D001659:Biliary Tract / Q000000981:diagnostic imaging; D001660:Biliary Tract Diseases / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D002648:Child; D002758:Cholangiography; D002779:Cholestasis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D012189:Retrospective Studies; D014463:Ultrasonography