title: Coincidental cases of primary sclerosing cholangitis and biliary atresia in siblings?
abstract: Familial cases of primary sclerosing cholangitis or biliary atresia have been reported, although genetic influences and immunopathological abnormalities in these diseases are considered to be obscure. We report a case of primary sclerosing cholangitis and biliary atresia in siblings with the observation of HLA-DR antigen expression in the abnormal bile duct epithelial cells.
authors.affiliation: Department of Paediatrics, Showa University Fujigaoka Hospital, Yokohama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Isoyama
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Ishikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Sanada
mesh_terms: D001653:Bile Ducts, Intrahepatic / Q000473:pathology; D001656:Biliary Atresia / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology; D001706:Biopsy; D002648:Child; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015209:Cholangitis, Sclerosing / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology; D003093:Colitis, Ulcerative / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D006684:HLA-DR Antigens / Q000235:genetics; D006801:Humans; D007223:Infant; D008099:Liver / Q000473:pathology; D008297:Male
chemical_list: D006684:HLA-DR Antigens