title: [Sporadic unilateral adrenal medullary hyperplasia--a rare cause of hypertension].
abstract: Sporadic adrenomedullary hyperplasia (AMH) is characterized by a clinical history of hypertension, increased plasma and/or urinary catecholamine levels and histomorphometric evidence of increased adrenal medullary mass in the absence of MEN 2 syndrome. The case of a 42-year-old female patient is reported who presented with typical clinical and laboratory findings of episodic hypertension and elevated plasma and urinary catecholamines. Sonography and computed tomography revealed no abnormality, but 131I-metaiodobenzylguanidine (131I-MIBG) scintigraphy showed increased uptake in the right adrenal. Transabdominal unilateral adrenalectomy was performed. The right adrenal gland was macroscopically inconspicuous. Upon histomorphometry, however, an increased adrenal medullary cell mass was shown, thus confirming AMH. Two years following surgery the patient is asymptomatic and normotensive.
authors.affiliation: Abteilung für Allgemeinchirurgie, Universität Hamburg.
authors.forename: A M
authors.initials: AM
authors.lastname: Stenger
authors.forename: A
authors.initials: A
authors.lastname: Frilling
authors.forename: S
authors.initials: S
authors.lastname: Schröder
authors.forename: C
authors.initials: C
authors.lastname: Odensaas
authors.forename: C E
authors.initials: CE
authors.lastname: Broelsch
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000473:pathology / Q000601:surgery*; D000313:Adrenal Medulla / Q000473:pathology*; D000315:Adrenalectomy; D000328:Adult; D002395:Catecholamines / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006965:Hyperplasia; D006973:Hypertension / Q000209:etiology* / Q000473:pathology / Q000601:surgery
chemical_list: D002395:Catecholamines
vernacular_title: Die sporadische unilaterale adrenomedulläre Hyperplasie--eine seltene Ursache des Bluthochdrucks.