Acute renal failure in a patient with chronic glomerulonephritis after the administration of luteinizing hormone-releasing hormone analogue given for rectal obstruction due to prostate cancer.
We report a case in which rectal obstruction due to prostate cancer was exacerbated due to an ileus after the administration of luteinizing hormone-releasing hormone analogue. The obstruction to led to copious vomiting, dehydration and renal failure which necessitated hemodialysis. Improvement of the patient was noted four weeks after the start of hormonal treatment with a decrease in rectal obstruction concomitant with decreases in testosterone and prostate specific antigen levels.
Takezawa
Y
Y
Department of Urology, Gunma University School of Medicine, Maebashi, Japan.
Nakano
K
K
Ohtake
N
N
Yamanaka
H
H
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D003681:Dehydration / Q000209:etiology; D005921:Glomerulonephritis / Q000150:complications*; D007987:Gonadotropin-Releasing Hormone / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D006801:Humans; D007415:Intestinal Obstruction / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D011471:Prostatic Neoplasms / Q000150:complications* / Q000188:drug therapy; D012002:Rectal Diseases / Q000188:drug therapy / Q000209:etiology*; D006435:Renal Dialysis; D014839:Vomiting / Q000209:etiology
D007987:Gonadotropin-Releasing Hormone