Learning and recall of form discriminations during reversible cooling deactivation of ventral-posterior suprasylvian cortex in the cat.
Extrastriate visual cortex of the ventral-posterior suprasylvian gyrus (vPS cortex) of freely behaving cats was reversibly deactivated with cooling to determine its role in performance on a battery of simple or masked two-dimensional pattern discriminations, and three-dimensional object discriminations. Deactivation of vPS cortex by cooling profoundly impaired the ability of the cats to recall the difference between all previously learned pattern and object discriminations. However, the cats' ability to learn or relearn pattern and object discriminations while vPS was deactivated depended upon the nature of the pattern or object and the cats' prior level of exposure to them. During cooling of vPS cortex, the cats could neither learn the novel object discriminations nor relearn a highly familiar masked or partially occluded pattern discrimination, although they could relearn both the highly familiar object and simple pattern discriminations. These cooling-induced deficits resemble those induced by cooling of the topologically equivalent inferotemporal cortex of monkeys and provides evidence that the equivalent regions contribute to visual processing in similar ways.
Lomber
S G
SG
Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA.
Payne
B R
BR
Cornwell
P
P
D000818:Animals; D001931:Brain Mapping; D002415:Cats / Q000033:anatomy & histology / Q000502:physiology*; D003337:Corpus Callosum / Q000601:surgery; D004192:Discrimination, Psychological / Q000502:physiology*; D000882:Haplorhini / Q000033:anatomy & histology; D007036:Hypothermia, Induced; D007858:Learning / Q000502:physiology*; D011939:Mental Recall / Q000502:physiology*; D009897:Optic Chiasm / Q000601:surgery; D010364:Pattern Recognition, Visual / Q000502:physiology*; D013045:Species Specificity; D014793:Visual Cortex / Q000502:physiology*