title: Autografting in chronic myeloid leukemia: an overview.
abstract: Autografting could become a promising treatment for patients with chronic myeloid leukemia (CML) who cannot undergo allogeneic bone marrow transplantation or failed to respond to recombinant alpha-interferon (IFN). In this review, we analyze the results which have been published for patients transplanted in chronic phase and which suggest that autografting could prolong survival, at least in some patients. We also discuss the different methods of purging whose clinical efficacy remains to be assessed.
authors.affiliation: Hôpital de Haut-Levêque, CHU Bordeaux, France.
authors.forename: J
authors.initials: J
authors.lastname: Reiffers
authors.forename: F X
authors.initials: FX
authors.lastname: Mahon
authors.forename: J M
authors.initials: JM
authors.lastname: Boiron
authors.forename: C
authors.initials: C
authors.lastname: Fabères
authors.forename: G
authors.initials: G
authors.lastname: Marit
authors.forename: P
authors.initials: P
authors.lastname: Cony-Makhoul
authors.forename: A
authors.initials: A
authors.lastname: Broustet
mesh_terms: D016465:Bone Marrow Purging / Q000379:methods; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use; D015466:Leukemia, Myeloid, Chronic-Phase / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate; D014182:Transplantation, Autologous
chemical_list: D007371:Interferon-gamma