Coronary vasomotor function in a normotensive, nondiabetic referral population with normal coronary arteriograms.
In a referral normal cardiac population, endothelium-independent coronary relaxation is nearly always normal, but endothelium-dependent relaxation may be depressed in a significant proportion of patients. Further study of the natural history of referral subjects with endothelial dysfunction is necessary to assess the potential cardiovascular risk of this finding in a presumed low-risk population.
Houghton
J L
JL
Division of Cardiology, Albany Medical College, Albany, New York, USA.
Smith
V E
VE
Breisblatt
W M
WM
Henches
N L
NL
Strogatz
D S
DS
Carr
A A
AA
D000109:Acetylcholine / Q000494:pharmacology; D000241:Adenosine / Q000494:pharmacology; D000328:Adult; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000187:drug effects / Q000502:physiology*; D005260:Female; D006334:Heart Function Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000494:pharmacology; D012016:Reference Values; D012039:Regional Blood Flow; D014664:Vasodilation / Q000187:drug effects; D014665:Vasodilator Agents / Q000494:pharmacology
D014665:Vasodilator Agents; D005996:Nitroglycerin; D000241:Adenosine; D000109:Acetylcholine