Use of urokinase in pregnancy. Two success stories.
Use of urokinase in treatment of deep venous thrombosis in pregnancy has been limited because of concerns about teratogenic effects and potential hemorrhage before and after delivery. However, reports to date have been encouraging and our experience is supportive. In the cases described here, urokinase thrombolytic therapy was effectively used to treat deep venous thrombosis in two pregnant patients without any apparent complications.
La Valleur
J
J
UMHC, Minneapolis 55455, USA. laval001@maroon.tc.umn.edu
Molina
E
E
Williams
P P
PP
Rolnick
S J
SJ
D000328:Adult; D005260:Female; D006801:Humans; D010960:Plasminogen Activators / Q000627:therapeutic use*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D015912:Thrombolytic Therapy; D013924:Thrombophlebitis / Q000188:drug therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*
D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator