Olfactory receptor-encoding genes and pseudogenes are expressed in humans.
A putative olfactory receptor-encoding gene was cloned from human genomic DNA and shown to be expressed by isolation of a full-length cDNA from olfactory tissue. A second cDNA clone was found to encode an olfactory receptor pseudogene. The expression of a pseudogene from the olfactory gene repertoire, in neurons which express only a single receptor type, implies that many neurons will be non-functional.
Crowe
M L
ML
Protein Engineering Department, Institute of Food Research, Reading, UK.
Perry
B N
BN
Connerton
I F
IF
D000595:Amino Acid Sequence; D001483:Base Sequence; D018076:DNA, Complementary; D006801:Humans; D008969:Molecular Sequence Data; D011544:Pseudogenes / Q000235:genetics; D011956:Receptors, Cell Surface / Q000737:chemistry / Q000235:genetics*; D043562:Receptors, G-Protein-Coupled; D018035:Receptors, Odorant / Q000235:genetics*
D018076:DNA, Complementary; C099706:OR3A1 protein, human; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D018035:Receptors, Odorant