[The hemostatic system in patients with viral hepatitis C].
Plasmic, platelet and fibrinolytic components of hemostasis were studied in 115 patients with severe viral hepatitis C transmitted fecally and orally. Most informative for determination of the disease severity and prognosis of onset of acute hepatic encephalopathy within 1-2 days were plasmic factor II, V, VII, X. In genesis of hemorrhagic syndrome of importance is procoagulant deficiency as a result of detective synthesis and consumption due to DIC syndrome rather than platelet disorder. In addition to procoagulant disorders there were low levels of plasminogen and its inhibitors changing with the disease severity.
Novozhenina
E V
EV
Kuznetsova
E N
EN
Poliakova
A M
AM
Danil'iants
I L
IL
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001777:Blood Coagulation; D005260:Female; D006470:Hemorrhage / Q000097:blood / Q000209:etiology*; D006501:Hepatic Encephalopathy / Q000209:etiology; D006526:Hepatitis C / Q000097:blood* / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013577:Syndrome
Sistema gemostaza u bol'nykh virusnym gepatitom C.