title: A novel sequence polymorphism in the promoter region of the human B2-bradykinin receptor gene.
abstract: The distribution of a nucleotide polymorphism in the core promoter of the human B2-bradykinin receptor gene was examined in the population of southern Germany. The allelic frequencies were 0.595 for C allele and 0.405 for the T allele. The allele frequencies were in Hardy-Weinberg equilibrium. This new marker provides a valuable tool to assess the risk for putative bradykinin-associated disorders with genetic determinism.
authors.affiliation: Children's Hospital, Department of Clinical Chemistry and Biochemistry, University of Munich, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Braun
authors.forename: E
authors.initials: E
authors.lastname: Maier
authors.forename: S
authors.initials: S
authors.lastname: Kammerer
authors.forename: B
authors.initials: B
authors.lastname: Müller
authors.forename: A A
authors.initials: AA
authors.lastname: Roscher
mesh_terms: D000483:Alleles; D001483:Base Sequence; D004247:DNA / Q000737:chemistry / Q000302:isolation & purification; D017931:DNA Primers; D004591:Electrophoresis, Polyacrylamide Gel; D005787:Gene Frequency; D005819:Genetic Markers; D005858:Germany; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic; D043782:Receptor, Bradykinin B2; D018002:Receptors, Bradykinin / Q000235:genetics*
chemical_list: D017931:DNA Primers; D005819:Genetic Markers; D043782:Receptor, Bradykinin B2; D018002:Receptors, Bradykinin; D004247:DNA