title: 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.
authors.affiliation: Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow, Essex, U.K.
authors.forename: J J
authors.initials: JJ
authors.lastname: Kulagowski
authors.forename: H B
authors.initials: HB
authors.lastname: Broughton
authors.forename: N R
authors.initials: NR
authors.lastname: Curtis
authors.forename: I M
authors.initials: IM
authors.lastname: Mawer
authors.forename: M P
authors.initials: MP
authors.lastname: Ridgill
authors.forename: R
authors.initials: R
authors.lastname: Baker
authors.forename: F
authors.initials: F
authors.lastname: Emms
authors.forename: S B
authors.initials: SB
authors.lastname: Freedman
authors.forename: R
authors.initials: R
authors.lastname: Marwood
authors.forename: S
authors.initials: S
authors.lastname: Patel
authors.forename: S
authors.initials: S
authors.lastname: Patel
authors.forename: C I
authors.initials: CI
authors.lastname: Ragan
authors.forename: P D
authors.initials: PD
authors.lastname: Leeson
mesh_terms: D000818:Animals; D002460:Cell Line; D018492:Dopamine Antagonists / Q000737:chemistry / Q000494:pharmacology*; D065127:Dopamine D2 Receptor Antagonists; D006801:Humans; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D011758:Pyrroles / Q000737:chemistry / Q000494:pharmacology*; D050638:Receptors, Dopamine D4
chemical_list: C099630:3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo(2,3-b)pyridine; C493599:DRD4 protein, human; D018492:Dopamine Antagonists; D065127:Dopamine D2 Receptor Antagonists; D011725:Pyridines; D011758:Pyrroles; D050638:Receptors, Dopamine D4