title: Human endothelin converting enzyme gene (ECE1) mapped to chromosomal region 1p36.1.
abstract: The chromosomal localization of the human endothelin converting enzyme gene (ECE1) has been identified. Southern blot analysis of human genomic DNA from human x mouse somatic cell hybrids demonstrated that ECE1 maps to chromosome 1. Fluorescence in situ hybridization of a digoxigenin-labeled human ECE1 probe to normal human metaphase chromosomes showed that the gene is located within chromosome band 1p36.1.
authors.affiliation: Department of Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women's Medical College, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Matsuoka
authors.forename: T
authors.initials: T
authors.lastname: Sawamura
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: M
authors.initials: M
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Furutani
authors.forename: T
authors.initials: T
authors.lastname: Ikura
authors.forename: T
authors.initials: T
authors.lastname: Shiraki
authors.forename: H
authors.initials: H
authors.lastname: Hoshikawa
authors.forename: K
authors.initials: K
authors.lastname: Shimada
authors.forename: K
authors.initials: K
authors.lastname: Tanzawa
authors.forename: T
authors.initials: T
authors.lastname: Masaki
mesh_terms: D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000235:genetics*; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics* / Q000648:ultrastructure; D015342:DNA Probes; D000072396:Endothelin-Converting Enzymes; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D008666:Metalloendopeptidases; D051379:Mice
chemical_list: D015342:DNA Probes; D016282:Aspartic Acid Endopeptidases; D008666:Metalloendopeptidases; C000606923:ECE1 protein, human; C000606925:Ece1 protein, mouse; D000072396:Endothelin-Converting Enzymes