[The prevalence of sleep-related breathing disorders in patients with implanted cardioverter-defibrillators. The effect on the incidence and circadian distribution of malignant ventricular tachyarrhythmias].
OBJECTIVE
To determine the prevalence of sleep-related breathing disorders (SRBD) on patients who, because of malignant ventricular tachyarrhythmias associated with cardiac disease, have an implanted cardioverter-defibrillator (ICD). It was also investigated whether the frequency and circadian distribution of spontaneous ventricular tachycardia and (or) fibrillation (VTF) can be influenced by SRBD.


METHODS
29 consecutive ICD patients (28 men, one woman; mean age 64 +/- 8 years) were investigated by multifunction recordings. 22 patients had coronary heart disease, and seven dilated cardiomyopathy. For each patient the number of VIF episodes per month were recorded, as well as the percentage distribution of the episodes during the day per hour and after grouping into four time periods.


RESULTS
SRBDs were recorded in 13 of the 29 patients (45%) (apnoea-hypopnea index [AHI] > 10). The other 16 patients had normal findings (AHI < or = 10). Mean frequency of the registered VTF attacks was similar in both groups (0.41/month with AHI < or = 10 vs 0.44/month with AHI > 10; difference not statistically significant). Averaged percentage distribution pattern showed a maximum frequency in both groups between 6 o'clock and 12 o'clock a.m. There was no significant increase of VTF during the night (10 o'clock p.m.-6 o'clock a.m.) in the group with SRBD (19% with AHI > 10 vs 18.2% with ATF < or = 10; difference not significant).


CONCLUSIONS
There was a high prevalence of SRBD in the patients with ICD and underlying cardiac disease. No influence of SRBD on frequency and circadian distribution of VTF was demonstrated in patients with ICD during long-term observation.
Fries
R
R
Abteilung Innere Medizin III, Universitätskliniken des Saarlandes, Homburg/Saar.
Heisel
A
A
Bauer
D
D
Fichter
J
J
Jung
J
J
Sybrecht
G W
GW
Schieffer
H
H
D000368:Aged; D016009:Chi-Square Distribution; D002940:Circadian Rhythm; D017147:Defibrillators, Implantable; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D017286:Polysomnography / Q000706:statistics & numerical data; D015995:Prevalence; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000453:epidemiology*; D018709:Statistics, Nonparametric; D017180:Tachycardia, Ventricular / Q000150:complications / Q000209:etiology* / Q000628:therapy; D013997:Time Factors
Prävalenz von schlafbezogenen Atmungsstörungen bei Patienten mit implantiertem Kardioverter-Defibrillator. Einfluss auf Häufigkeit und tageszeitliche Verteilung von malignen ventrikulären Tachyarrhythmien.