[Radionuclide purity of 99mTC eluate for use in nuclear medicine].
The radionuclide purity of 99mTc eluates obtained by the elution on the commercially available 99Mo/99mTc generators based of fission-produced 99Mo was determined by gamma spectrometry. The following parameters were determined: the content of radionuclide impurities and their distribution in the eluates during the 10 days elution of the generator. The main radiocontaminant is 99Mo. In all eluates three long-living gamma emitters 103Ru, 106Ru and 131I were found. 125Sb appears only in the first three eluates. After that its activity falls under the detection limit. These four radioisotopes are fission products. They are formed in the fission of 235U and follow 99Mo during the separation and purification steps. It was found that the highest activity in eluates is due to the presence of 103Ru. By comparison of the obtained results and the prescribed criteria of the radio-nuclide purity of 99mTc eluates it could be concluded that all the found radionuclide impurities are under the permitted levels. Therefore 99mTc eluates fulfill the criteria for the nuclear-medical applications.
Vucina
J L
JL
Institut za nuklearne nauke Vinca, Beograd.
D006801:Humans; D011876:Radionuclide Generators; D013667:Technetium / Q000592:standards*
D013667:Technetium
Radionuklidna cistoća eluata 99mTc za primenu u nuklearnoj medicini.