[Role of intercellular interactions in tumor progression and metastasis].
Cell-cell and cell-substratum interactions are mediated by specific cell adhesion molecules. These cell adhesion molecules play a central role in normal tissue organization and cell migration, as well as in tumor growth and metastasis. There is growing evidence that carbohydrates profiles of tumor cells change during malignant progression. These cell-surface carbohydrates may play an important role in intercellular interactions, as a ligands for endogenous cellular lectins.
Duś
D
D
Zakład Immunologii Nowotworów.
D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology; D002471:Cell Transformation, Neoplastic / Q000378:metabolism*; D006801:Humans; D037102:Lectins / Q000502:physiology; D008024:Ligands; D009362:Neoplasm Metastasis / Q000503:physiopathology*; D013499:Surface Properties
D015815:Cell Adhesion Molecules; D037102:Lectins; D008024:Ligands
Rola oddziaływań miedzykomórkowych w procesie inwazji i powstawania przerzutów.