[Expression of recombinant human hemoglobin in plants].
Human utilization of recombinant proteins of therapeutical interest, as hemoglobin, implies that the transgenic host allows a low cost production of the active proteins with minimal risks of pathogen contamination. In this regard, the use of transgenic plants could be of great interest. In particular, the systems based on plants could be one of the most economical transgenic system, compared with the others, because biomass obtention in fields is not expensive.
Dieryck
W
W
INSERM U299, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
Gruber
V
V
Baudino
S
S
Lenee
P
P
Pagnier
J
J
Merot
B
B
Poyart
C
C
D002240:Carbohydrate Sequence; D006454:Hemoglobins / Q000096:biosynthesis / Q000191:economics / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D030821:Plants, Genetically Modified; D011401:Promoter Regions, Genetic; D011499:Protein Processing, Post-Translational; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000191:economics; D013347:Subcellular Fractions / Q000378:metabolism; D014170:Transformation, Genetic
D006454:Hemoglobins; D011994:Recombinant Proteins
Expression d'hémoglobine humaine recombinante dans les plantes.