Cloning and partial structure of the gene encoding human tissue inhibitor of metalloproteinases-3.
Using a cDNA probe, two genomic clones were obtained encoding the human tissue inhibitor of metalloproteinases-3 (TIMP-3). Analysis of these clones showed that they contained four distal exons and three introns of the gene. Although the intron-exon structure is similar to that of the timp1 gene, the first intron of the timp3 gene is much longer, being at least 17.5 kb in size.
Hammani
K
K
Department of Pediatrics, Childrens Hospital Los Angeles, CA 90054-0700, USA.
Henriet
P
P
Silbiger
S M
SM
DeClerck
Y A
YA
D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics*; D019717:Tissue Inhibitor of Metalloproteinase-3
D011506:Proteins; D019717:Tissue Inhibitor of Metalloproteinase-3; D004247:DNA