The human gene encoding the heavy chain of the major histocompatibility complex class I-like Fc receptor (FCGRT) maps to 19q13.3.
FcRn is an Fc receptor that structurally resembles the major histocompatibility complex class I molecule. In this study, we isolated the human gene encoding the heavy chain of FcRn (FCGRT) and mapped it by fluorescence in situ hybridization to chromosome band 19q13.3. Thus, like its mouse counterpart, the human FCGRT gene is located outside the major histocompatibility complex.
Kandil
E
E
Department of Biochemistry, Hokkaido University School of Medicine, Sapporo, Japan.
Egashira
M
M
Miyoshi
O
O
Niikawa
N
N
Ishibashi
T
T
Kasahara
M
M
Miyosi
O
O
D000818:Animals; D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics*; D018076:DNA, Complementary / Q000235:genetics; D015723:Gene Library; D005796:Genes; D015395:Histocompatibility Antigens Class I / Q000737:chemistry; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008285:Major Histocompatibility Complex; D051379:Mice; D011961:Receptors, Fc / Q000737:chemistry / Q000235:genetics*; D013045:Species Specificity
D018076:DNA, Complementary; D015395:Histocompatibility Antigens Class I; D011961:Receptors, Fc