title: [Felty syndrome: a therapy-resistant variant of chronic rheumatoid arthritis? 2 case reports and literature review].
abstract: Felty's syndrome is a rare but serious extra-articular manifestation of rheumatoid arthritis. Morbidity as well as mortality are increased on account of greater susceptibility to infectious agents. We report on two patients suffering from Felty's syndrome who were successfully treated by cyclophosphamide. A review of the literature with special regard to treatment of Felty's syndrome is given.
authors.affiliation: Medizinische Klinik, Kantonsspital Luzern.
authors.forename: R
authors.initials: R
authors.lastname: Brücker
authors.forename: U
authors.initials: U
authors.lastname: Schlumpf
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D005258:Felty Syndrome / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents; D003520:Cyclophosphamide
vernacular_title: Das Felty-Syndrom: eine therapierefraktäre Variante der chronischen Polyarthritis? Zwei Fallberichte und Literaturübersicht.