title: Key enzymes in the biosynthesis of purines and pyrimidines: their regulation by allosteric effectors and by phosphorylation.
authors.affiliation: Department of Biochemistry, University of Dundee, Scotland, U.K.
authors.forename: E A
authors.initials: EA
authors.lastname: Carrey
mesh_terms: D000494:Allosteric Regulation; D000582:Amidophosphoribosyltransferase / Q000378:metabolism; D000595:Amino Acid Sequence; D000818:Animals; D001221:Aspartate Carbamoyltransferase / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D002223:Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D004080:Dihydroorotase / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D009097:Multienzyme Complexes / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D010766:Phosphorylation; D011687:Purines / Q000096:biosynthesis*; D011743:Pyrimidines / Q000096:biosynthesis*; D017386:Sequence Homology, Amino Acid
chemical_list: C033626:CAD trifunctional enzyme; D004798:Enzymes; D009097:Multienzyme Complexes; D011687:Purines; D011743:Pyrimidines; D001221:Aspartate Carbamoyltransferase; D000582:Amidophosphoribosyltransferase; D004080:Dihydroorotase; D002223:Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); C030985:purine