title: Plant polyphenols: free radical scavengers or chain-breaking antioxidants?
abstract: There is increasing interest in the biological effects of tea- and wine-derived polyphenols and many studies in vitro and in vivo are demonstrating their antioxidant properties. Tea is a major source of dietary polyphenols and an even richer source of the flavanols, the catechins and catechin/gallate esters. Although there are limited studies on the bioavailability of the polyphenols, the absorption of flavanols in humans has been shown. The studies described in this chapter discuss the relative antioxidant potentials of the polyphenolic flavonoids in vitro against radicals generated in the aqueous phase in comparison with their relative effectiveness as antioxidants against propagating lipid peroxyl radicals, and how their activity influences that of alpha-tocopherol in low-density lipoproteins exposed to oxidative stress.
authors.affiliation: Division of Biochemistry and Molecular Biology, UMDS-Guy's Hospital, London, U.K.
authors.forename: C
authors.initials: C
authors.lastname: Rice-Evans
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D005419:Flavonoids; D016166:Free Radical Scavengers / Q000737:chemistry*; D006801:Humans; D010636:Phenols / Q000737:chemistry*; D010944:Plants / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D059808:Polyphenols
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D016166:Free Radical Scavengers; D010636:Phenols; D011108:Polymers; D059808:Polyphenols