title: Echocardiographic evaluation of the effects of medetomidine and xylazine in dogs.
abstract: The echocardiographic effects of medetomidine and xylazine were evaluated in 6 healthy dogs. Values for echocardiographic variables were significantly different from pre-treatment values after administration of both drugs. The effects of medetomidine were similar to that of xylazine. Because of their cardiac depressant effects, both drugs should be used with care in sick dogs.
authors.affiliation: Department of Companion Animal Medicine and Surgery, University of Queensland.
authors.forename: J S
authors.initials: JS
authors.lastname: Rand
authors.forename: W T
authors.initials: WT
authors.lastname: Reynolds
authors.forename: J
authors.initials: J
authors.lastname: Priest
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D004285:Dogs; D004452:Echocardiography / Q000662:veterinary; D005260:Female; D006321:Heart / Q000033:anatomy & histology / Q000187:drug effects* / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000494:pharmacology*; D007093:Imidazoles / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D020926:Medetomidine; D012149:Restraint, Physical / Q000662:veterinary*; D013997:Time Factors; D014991:Xylazine / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D006993:Hypnotics and Sedatives; D007093:Imidazoles; D014991:Xylazine; D020926:Medetomidine