[The small Alu-like RNA from the A-431 cell line specifically regulates the activity of the RNA polymerase III from human placental nuclei].
The influence of small Alu-like RNA, isolated from specific RNP complexes (alpha-RNP), on the activity of RNA polymerase III in cell-free system has been studied. The RNAs transcribed in vitro from Alu-DNA template (BLUR, 8) were isolated and subjected to polyacrylamide gel electrophoresis. A specific stimulation of RNA polymerase III activity by alpha-RNA was demonstrated.
Sedova
V M
VM
Turoverova
L V
LV
Konstantinova
I M
IM
D000547:Amantadine / Q000494:pharmacology; D002294:Carcinoma, Squamous Cell; D002467:Cell Nucleus / Q000187:drug effects / Q000201:enzymology*; D005260:Female; D006801:Humans; D010920:Placenta / Q000187:drug effects / Q000201:enzymology* / Q000648:ultrastructure; D011247:Pregnancy; D012320:RNA Polymerase III / Q000037:antagonists & inhibitors / Q000187:drug effects / Q000378:metabolism*; D012334:RNA, Neoplasm / Q000235:genetics / Q000494:pharmacology; D012343:RNA, Transfer / Q000494:pharmacology; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D017411:Ribonucleoproteins, Small Nuclear / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D012334:RNA, Neoplasm; D017411:Ribonucleoproteins, Small Nuclear; D012343:RNA, Transfer; D000547:Amantadine; D012320:RNA Polymerase III
Malaia Alu-podobnaia RNK iz kletok linii A-431 spetsificheski reguliruet aktivnost' RNK-polimerazy III iz iader platsenty cheloveka.