Inhibitors of trypanothione reductase as potential antitrypanosomal drugs.
Chan
C
C
Department of Pharmacy, University of Manchester, U.K.
Yin
H
H
Garforth
J
J
McKie
J H
JH
Jaouhari
R A
RA
Douglas
K T
KT
Fairlamb
A H
AH
Croft
S L
SL
D000818:Animals; D001665:Binding Sites; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D005978:Glutathione / Q000031:analogs & derivatives / Q000378:metabolism; D019803:Glutathione Disulfide; D006801:Humans; D009247:NADH, NADPH Oxidoreductases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D010640:Phenothiazines / Q000737:chemistry / Q000494:pharmacology; D013095:Spermidine / Q000031:analogs & derivatives / Q000378:metabolism; D014344:Trypanocidal Agents / Q000737:chemistry / Q000494:pharmacology*
D004791:Enzyme Inhibitors; D010640:Phenothiazines; D014344:Trypanocidal Agents; C044809:trypanothione; D009247:NADH, NADPH Oxidoreductases; C049608:trypanothione reductase; D005978:Glutathione; D013095:Spermidine; D019803:Glutathione Disulfide