title: Invasive malignant fibrous histiocytoma in a cow.
abstract: An invasive malignant fibrous histiocytoma associated with the left cornual process, and causing lysis of the frontal bone, was diagnosed in a cow. The mass compressed the left cerebral hemisphere focally and extended into the frontal sinus and ethmoid and nasal turbinates. It was composed of pleomorphic to spindle-shaped cells with ultra-structural evidence of fibroblastic, myofibroblastic, and fibrohistiocytic differentiation. Trauma and chronic inflammation may be predisposing factors for development of neoplasia in cattle.
authors.affiliation: Department of Pathobiology, College of Veterinary Medicine, Auburn University, AL 36849-5519, USA.
authors.forename: E A
authors.initials: EA
authors.lastname: Sartin
authors.forename: J A
authors.initials: JA
authors.lastname: Hudson
authors.forename: G A
authors.initials: GA
authors.lastname: Herrera
authors.forename: A M
authors.initials: AM
authors.lastname: Dickson
authors.forename: D F
authors.initials: DF
authors.lastname: Wolfe
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D006733:Horns / Q000293:injuries / Q000601:surgery; D009361:Neoplasm Invasiveness; D009369:Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*