[Evaluation of ambroxol given prenatally and postnatally on gas exchange in the newborn with respiratory distress syndrome].
160 newborns were observed to compare the influence of combine treatment with ambroxol (Lasolvan-Boehringer Ingelheim) (antenatal and postnatal) versus postnatal administration of this drug on gas exchange and reduction of ventilatory settings in newborns with RDS. In 53% of cases the preparation was given both: pre- and postnatal and 47% of newborns were treated only postnatal. The results of stimulation of lung maturity "before and after" versus "after" delivery were better in the first group, however in some parameters we did not found statistical differences.
Sackey
S
S
Kliniki Neonatologii Instytutu Ginekologii i Połoznictwa AM w Poznaniu.
Gadzinowski
J
J
Szymankiewicz
M
M
Breborowicz
G H
GH
Rudnicki
J
J
Patalan
J
J
Rózewicki
K
K
D000551:Ambroxol / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005100:Expectorants / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000187:drug effects / Q000254:growth & development; D011181:Postnatal Care; D011295:Prenatal Care; D011659:Pulmonary Gas Exchange / Q000187:drug effects*; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy*
D005100:Expectorants; D000551:Ambroxol
Ocena wpływu ambroksolu podawanego prenatalnie i pourodzeniowo na wymiane gazowa u noworodka z zespołem zaburzeń oddychania.