title: Breast cancer chemoprevention: clinical trials and research.
abstract: We have reviewed the literature regarding the chemoprevention of breast cancer. Several clinical trials using retinoid, tamoxifen, or low-fat dietary intervention for the prevention of breast cancer are ongoing. In the next few years, the implementation of these clinical chemoprevention trials will take place. Moreover, combinations of such chemopreventive agents, as well as the development of new chemopreventive compounds, will require testing in clinical settings. Even though there is probably a substantial delay before such chemopreventive approaches have a significant effect, it is clear that chemoprevention will complement other approaches in controlling breast cancer.
authors.affiliation: Operation Center, Kanazawa University Hospital, School of Medicine, Kanazawa University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Noguchi
authors.forename: D P
authors.initials: DP
authors.lastname: Rose
authors.forename: I
authors.initials: I
authors.lastname: Miyazaki
mesh_terms: D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000178:diet therapy / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D018752:Diet, Fat-Restricted; D006801:Humans
chemical_list: D016588:Anticarcinogenic Agents