Primary carcinoid tumor of the liver: report of four resected cases including one with gastrin production.
Four cases of primary hepatic carcinoid were identified during a retrospective study of liver resections for primary tumor. The cases included two adult males, one adult female, and a 9-year-old boy in whom gastrin levels were documented. The estimation of gastrin levels was prompted by symptoms suggestive of acid-peptic disease. One patient died postoperatively. The other three are alive and well at 3 years, 2 years, and at 1 year, respectively, after surgery, outcomes distinctly different from hepatocellular carcinomas. Diagnostic difficulties may be experienced in histologic assessment, and this may require recourse to immunohistochemistry and electron microscopy. Long-term follow-up and careful exclusion of a possible primary elsewhere are necessary for establishing the primary nature of liver carcinoids.
Krishnamurthy
S C
SC
Department of Pathology, Tata Memorial Hospital, Bombay, India.
Dutta
V
V
Pai
S A
SA
Kane
S V
SV
Jagannath
P
P
Desouza
L J
LJ
Deshpande
R
R
Desai
P B
PB
D000328:Adult; D002276:Carcinoid Tumor / Q000378:metabolism* / Q000473:pathology / Q000601:surgery*; D002648:Child; D017809:Fatal Outcome; D005260:Female; D005755:Gastrins / Q000097:blood / Q000378:metabolism*; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged
D005755:Gastrins