title: Impact of reduction of lead in gasoline on the blood and hair lead levels in the population of Tarragona Province, Spain, 1990-1995.
abstract: The limitation in the use of lead in Spanish gasoline has induced a resulting decrease in atmospheric lead concentrations, a remarkable reduction in the lead levels of edible vegetables, as well as a marked decrease in the dietary lead intake of the population of Tarragona Province (Catalonia, N.E. Spain). The present study evaluates the impact of such decreases on blood lead values and hair lead concentrations in an adult and children population of that region. A total of 250 adult participants between 16-65 years of age and 252 children were included in the study. Blood and hair samples were subjected to lead analyses by graphite furnace atomic absorption spectrophotometry and inductively coupled plasma spectrometry, respectively. A substantial decline in both, blood lead levels in adults (47.5%) and lead concentrations in children's hair (53%) was observed. During the period 1990-1995, blood levels were reduced from 12.0 micrograms dl-1 to 6.3 micrograms dl-1, while the hair lead concentrations decreased from 8.8 micrograms g-1 to 4.1 micrograms g-1. These decreases were noted for all the subgroups (sex, age and place of residence) examined, and were mainly attributable to the reduced leaded gasoline consumption.
authors.affiliation: Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, Reus, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Schuhmacher
authors.forename: M
authors.initials: M
authors.lastname: Bellés
authors.forename: A
authors.initials: A
authors.lastname: Rico
authors.forename: J L
authors.initials: JL
authors.lastname: Domingo
authors.forename: J
authors.initials: J
authors.lastname: Corbella
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D004781:Environmental Exposure / Q000032:analysis*; D005260:Female; D005742:Gasoline; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007854:Lead / Q000032:analysis* / Q000097:blood; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013030:Spain; D013997:Time Factors
chemical_list: D005742:Gasoline; D007854:Lead