Core body temperature during menopausal hot flushes.
OBJECTIVE
To measure core body temperature by ingested radiotelemetry pill and rectal temperature during menopausal hot flushes under controlled laboratory conditions.


METHODS
Patients were recorded during sleep using both methods in a sound-proofed, temperature and humidity-controlled laboratory room.


METHODS
University medical center.


METHODS
Eight postmenopausal women who were amenorrheic for > or = 1 year and reported frequent hot flushes.


RESULTS
Thirty-seven hot flushes were detected by criterion increases in sternal skin conductance level. Significant increases in telemetered but not rectal temperature occurred before 24 of the hot flushes.


CONCLUSIONS
Core body temperature elevations precede a majority of menopausal hot flushes and serve as one trigger of this heat-loss phenomenon.
Freedman
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Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Woodward
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S
D001831:Body Temperature; D001833:Body Temperature Regulation; D002979:Climacteric; D005260:Female; D006801:Humans; D008593:Menopause / Q000502:physiology*