An extended nomenclature of the canine karyotype.
In contrast to many other animals, knowledge about the canine karyotype is quite sparse. This is due in part to the rather difficult canine karyotypic pattern. Except for the X and the Y chromosome, there are only acrocentric chromosomes, which appear to be quite small and difficult to identify unambiguously. In previous reports, schematic representations of the canine karyotype have been described. However, a nomenclature comparable to that of the human karyotype or the karyotypes of sheep, cattle, or goats does not yet exist for the dog. Based on high-resolution banding of metaphase chromosomes from canine fibroblasts, we propose an ideogram of the canine karyotype with 460 numbered bands and characteristic landmarks. In addition, the centromere positions of the canine chromosomes are determined by a combined GTG-banding/FISH approach, and the R- and G-banding patterns are compared.
Reimann
N
N
Center for Human Genetics and Genetic Counselling, University of Bremen, Germany.
Bartnitzke
S
S
Bullerdiek
J
J
Schmitz
U
U
Rogalla
P
P
Nolte
I
I
Rønne
M
M
D000818:Animals; D001483:Base Sequence; D002478:Cells, Cultured; D002503:Centromere / Q000648:ultrastructure; D002871:Chromosome Banding / Q000662:veterinary; D002875:Chromosomes / Q000145:classification / Q000235:genetics / Q000648:ultrastructure; D004276:DNA, Satellite / Q000235:genetics; D004285:Dogs / Q000235:genetics*; D005347:Fibroblasts / Q000648:ultrastructure; D005819:Genetic Markers; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping / Q000662:veterinary*; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D013045:Species Specificity; D009626:Terminology as Topic
D004276:DNA, Satellite; D005819:Genetic Markers