Prolonged remission of SLE-associated polyradiculoneuropathy after a single course of intravenous immunoglobulin.
Polyradiculoneuropathy is a rare and potentially severe complication of systemic lupus erythematosus (SLE). Treatment is not codified and response to corticosteroid is inconstant. We report the case of a patient with severe SLE-associated polyradiculoneuropathy and autoimmune thrombocytopenia. Dramatic neurologic improvement and correction of thrombocytopenia were observed after a single course of high-dose intravenous immunoglobulin infusions (IVIg, 2g/kg body weight). Our case suggests that IVIg may be effective in the treatment of this unusual condition.
Lesprit
P
P
Service de Médecine Interne, Hôpital Henri Mondor, Créteil, France.
Mouloud
F
F
Bierling
P
P
Schaeffer
A
A
Cesaro
P
P
Brun-Buisson
C
C
Godeau
B
B
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D011129:Polyradiculoneuropathy / Q000150:complications / Q000628:therapy*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000628:therapy; D012074:Remission Induction; D013997:Time Factors
D016756:Immunoglobulins, Intravenous