title: Inhibitors of trypanothione reductase as potential antitrypanosomal drugs.
authors.affiliation: Department of Pharmacy, University of Manchester, U.K.
authors.forename: C
authors.initials: C
authors.lastname: Chan
authors.forename: H
authors.initials: H
authors.lastname: Yin
authors.forename: J
authors.initials: J
authors.lastname: Garforth
authors.forename: J H
authors.initials: JH
authors.lastname: McKie
authors.forename: R A
authors.initials: RA
authors.lastname: Jaouhari
authors.forename: K T
authors.initials: KT
authors.lastname: Douglas
authors.forename: A H
authors.initials: AH
authors.lastname: Fairlamb
authors.forename: S L
authors.initials: SL
authors.lastname: Croft
mesh_terms: D000818:Animals; D001665:Binding Sites; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D005978:Glutathione / Q000031:analogs & derivatives / Q000378:metabolism; D019803:Glutathione Disulfide; D006801:Humans; D009247:NADH, NADPH Oxidoreductases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D010640:Phenothiazines / Q000737:chemistry / Q000494:pharmacology; D013095:Spermidine / Q000031:analogs & derivatives / Q000378:metabolism; D014344:Trypanocidal Agents / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D010640:Phenothiazines; D014344:Trypanocidal Agents; C044809:trypanothione; D009247:NADH, NADPH Oxidoreductases; C049608:trypanothione reductase; D005978:Glutathione; D013095:Spermidine; D019803:Glutathione Disulfide