Angioimmunoblastic lymphadenopathy: an etiology for gastrointestinal lymphomatous polyposis.
We describe a case of angioimmunoblastic lymphadenopathy with multiple polyps of the gastrointestinal tract. The patient presented with fever, abdominal mass, ascites, diarrhea, generalized lymphadenopathy, anemia, and marked peripheral eosinophilia. She had multiple polyps in the colon, as well as in the stomach and duodenum. Histology of a colonic polyp showed involvement by angioimmunoblastic lymphadenopathy. The patient responded initially to combination chemotherapy, with total disappearance of polyps. However, she succumbed later to infections. Angioimmunoblastic lymphadenopathy, although rare, should be included as a cause of lymphomatous polyposis of the gastrointestinal tract.
Goenka
M K
MK
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vaiphei
K
K
Nagi
B
B
Sriram
P V
PV
Joshi
K
K
Kochhar
R
R
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D007417:Intestinal Polyps / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D011239:Prednisolone / Q000008:administration & dosage; D012074:Remission Induction; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone