title: Orbital lesions in the blue rubber bleb nevus syndrome.
abstract: OBJECTIVE
  To identify ophthalmologic manifestations of the blue rubber bleb nevus syndrome, a rare cutaneovisceral hemangiomatosis.
  
  
  METHODS
  The authors report two patients with a diagnosis of blue rubber bleb nevus syndrome with orbital hemangiomas.
  
  
  RESULTS
  In one patient, the orbital lesion presented with signs and symptoms similar to an orbital varix and in the other with lid ecchymosis from an eyelid lesion.
  
  
  CONCLUSIONS
  Patients with the blue rubber bleb nevus syndrome may have vascular orbital lesions associated with intermittent proptosis. Ophthalmologists should be familiar with the syndrome and its life-threatening complication of gastrointestinal hemorrhage.
authors.affiliation: Department of Ophthalmology, University of Colorado Health Science Center, Denver CO 80262, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: McCannel
authors.forename: J
authors.initials: J
authors.lastname: Hoenig
authors.forename: J
authors.initials: J
authors.lastname: Umlas
authors.forename: J J
authors.initials: JJ
authors.lastname: Woog
authors.forename: A N
authors.initials: AN
authors.lastname: Newman
authors.forename: J B
authors.initials: JB
authors.lastname: Bateman
mesh_terms: D000328:Adult; D002648:Child; D005094:Exophthalmos / Q000209:etiology; D005142:Eyelid Neoplasms / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000150:complications; D006392:Hemangioma, Cavernous / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D018329:Nevus, Blue / Q000150:complications / Q000175:diagnosis*; D009915:Orbit / Q000473:pathology; D009918:Orbital Neoplasms / Q000150:complications / Q000175:diagnosis*; D012878:Skin Neoplasms / Q000150:complications / Q000175:diagnosis*; D013577:Syndrome; D014057:Tomography, X-Ray Computed