Diabetic complications and the mechanism of the hyperglycaemia-induced damage to the mt DNA of cultured vascular endothelial cells: (I) Characterisation of the 4977 base pair deletion and 13 bp flanking repeats.
Egawhary
D N
DN
Dept. of Biological Sciences, University of Warwick, Coventry, UK.
Swoboda
B E
BE
Chen
J
J
Easton
A J
AJ
Vince
F P
FP
D000595:Amino Acid Sequence; D001483:Base Sequence; D002478:Cells, Cultured; D004249:DNA Damage; D004272:DNA, Mitochondrial / Q000235:genetics*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics*; D004730:Endothelium, Vascular / Q000378:metabolism; D006801:Humans; D006943:Hyperglycemia / Q000378:metabolism; D008969:Molecular Sequence Data; D017382:Reactive Oxygen Species / Q000378:metabolism; D012091:Repetitive Sequences, Nucleic Acid; D017384:Sequence Deletion
D004272:DNA, Mitochondrial; D017382:Reactive Oxygen Species