Strategies for the prevention of senile (type II) osteoporosis: an update.
Hip fractures in the elderly represent a global issue, associated with significant morbidity and mortality. Considering the magnitude of the problem, any substantial reduction in the hip fracture burden depends on prevention. In view of the complex pathogenesis of senile (type II) osteoporosis, preventive strategies should focus on the frequency of falling in the elderly as well as on the prevalence of compromised femoral integrity as a consequence of bone loss. Although many risk factors for senile osteoporosis are potentially preventible or reversible with targeted interventions, the beneficial effects of most strategies have not yet been adequately documented, indicating the need for additional long-term controlled studies.
Boonen
S
S
Department of Internal Medicine, Katholieke Universiteit, Leuven, Belgium.
Dequeker
J
J
D000058:Accidental Falls / Q000517:prevention & control; D015519:Bone Density; D002118:Calcium / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy; D005260:Female; D006620:Hip Fractures / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000503:physiopathology / Q000517:prevention & control*; D015663:Osteoporosis, Postmenopausal / Q000150:complications / Q000503:physiopathology / Q000517:prevention & control
D002118:Calcium