title: Balloon aortic valvuloplasty in elderly patients at high risk for surgery, or inoperable. Immediate and mid-term results.
abstract: Although aortic valve replacement is undoubtedly the treatment of choice for aortic valve stenosis, balloon aortic valvuloplasty may represent the only possible treatment for some frail elderly patients who may have additional medical problems. We evaluated immediate and 1-year results of balloon aortic valvuloplasty in 86 patients > or = 80 years with severe aortic stenosis. Mean age was 84 +/- 3 years. Forty-four % were 85 years or older. Mean gradient decreased from 68 to 26 mm Hg and valve area increased from 0.53 to 0.96 cm2 (P<0.05). There were two per-procedural deaths. No local vascular complication was observed. During the follow-up (13 +/- 9 months), 27 patients died, four had repeat balloon aortic valvuloplasty and eight underwent aortic valve replacement. Persistent clinical improvement was observed in 78% of the surviving patients. One-year actuarial survival rate was 73%. Balloon aortic valvuloplasty appears to be a safe and valuable technique in cases where surgery cannot be performed or carries a very high risk.
authors.affiliation: Hôpital Charles Nicolle, Vacomed Research Group, Rouen, France.
authors.forename: H
authors.initials: H
authors.lastname: Eltchaninoff
authors.forename: A
authors.initials: A
authors.lastname: Cribier
authors.forename: C
authors.initials: C
authors.lastname: Tron
authors.forename: F
authors.initials: F
authors.lastname: Anselme
authors.forename: R
authors.initials: R
authors.lastname: Koning
authors.forename: R
authors.initials: R
authors.lastname: Soyer
authors.forename: B
authors.initials: B
authors.lastname: Letac
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D002404:Catheterization; D017023:Coronary Angiography; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome