title: Registration and alignment of three-dimensional images: an interactive visual approach.
abstract: A three-dimensional registration and alignment algorithm was developed to align single photon emission computed tomography examinations and magnetic resonance images. Operators manipulated images interactively with real-time visual feedback, with use of both internal and surface features to achieve accurate alignment. Operators aligned five brain phantom examinations (accuracy, 1.6 pixels; consistency, 0.7 pixels) and eight patient brain examinations (consistency, 0.5 pixels).
authors.affiliation: Department of Radiology, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: I H
authors.initials: IH
authors.lastname: Habboush
authors.forename: K D
authors.initials: KD
authors.lastname: Mitchell
authors.forename: R V
authors.initials: RV
authors.lastname: Mulkern
authors.forename: P D
authors.initials: PD
authors.lastname: Barnes
authors.forename: S T
authors.initials: ST
authors.lastname: Treves
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D003545:Cysteine / Q000031:analogs & derivatives*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015609:Organotechnetium Compounds; D010091:Oximes; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D019690:Technetium Tc 99m Exametazime; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D013794:Thallium Radioisotopes; D019690:Technetium Tc 99m Exametazime; C059659:technetium Tc 99m bicisate; D003545:Cysteine