No evidence of contact sensitization to acyclovir in acute dermatitis of the lips following local application of Zovirax cream.
We report 4 patients with acute contact dermatitis of the lips following application of Zovirax cream. Patch tests with pure acyclovir, and combinations of the ingredients of the cream base, with and without acyclovir, provided no evidence of sensitization to any constituents of the cream.
Koch
P
P
Hautklinik Universität des Saarlandes, Homburg/Saar, Germany.
D000208:Acute Disease; D000212:Acyclovir / Q000009:adverse effects*; D000293:Adolescent; D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects*; D002613:Cheilitis / Q000139:chemically induced* / Q000175:diagnosis; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D010328:Patch Tests
D000998:Antiviral Agents; D000212:Acyclovir