Indications and results of arterial stents for occlusive disease.
The application of stents for treatment of peripheral arterial occlusive disease has gained widespread clinical use, but their safety and efficacy remain unclear. Stent technology is still evolving, and long-term follow-up data are sorely needed. Stents have had good success in providing a scaffold to maintain the intraluminal structure and patency of an artery. As such, stents appear to play a role in improving early results after failed or inadequate balloon angioplasty. However, stents do not prevent restenosis due to intimal hyperplasia. Furthermore, stents may be thrombogenic and prone to extrinsic compression in the peripheral position. Thus patency results are clearly worse in the femoral artery (47% at 3 years) than in the iliac artery (82-84% at 6-24 months). Furthermore, there is no evidence so far that stents improve long-term patency over standard balloon angioplasty without stents; and complication rates of stent procedures are generally 10%. Currently in the United States stents are approved for use in the iliac artery position. However, routine use of stents cannot be recommended until studies demonstrate that the results with stents are better than those with balloon angioplasty alone.
Ahn
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Department of Surgery, Section of Vascular Surgery, UCLA Center for the Health Sciences, 100 UCLA Medical Plaza, Suite 510, Los Angeles, California 90024, U.S.A.
Concepcion
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B
D000800:Angioplasty, Balloon; D001157:Arterial Occlusive Diseases / Q000628:therapy*; D004867:Equipment Design; D004868:Equipment Failure; D005500:Follow-Up Studies; D006801:Humans; D015607:Stents