[Digoxin poisoning treated with Digibind].
A case of digoxin intoxication and hyperkalaemia causing cardiac arrest in a 63-year-old female who had undergone cardiac surgery is presented. Symptomatic treatment was given. However, as the patient continued to be unstable we introduced digoxin Fab-antibody in the treatment. The patient changed her heart rhythm from atrioventricular conduction block to atrial fibrillation within a few minutes and recovered later on. The pharmacology and the indications for treatment with digoxin Fab-antibody fragments are discussed.
Andersen
J B
JB
Thoraxkirurgisk afdeling T, Odense Universitetshospital.
Sørensen
B U
BU
Andersen
L I
LI
D000059:Accidents; D000931:Antidotes / Q000008:administration & dosage*; D004077:Digoxin / Q000506:poisoning*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000008:administration & dosage*; D008875:Middle Aged
D000931:Antidotes; D007140:Immunoglobulin Fab Fragments; C050199:digoxin antibodies Fab fragments; D004077:Digoxin
Digoxinintoksikation behandlet med Digibind.