title: Novel 28-kDa secretory protein from rat olfactory epithelium.
abstract: We have isolated a novel secretory 28-kDa protein which is an abundant component of the rat olfactory mucosa. The partial sequence of the 28-kDa protein has been determined. The amino acid sequence of the 28-kDa protein is similar to that of non-selenium glutathione peroxidase from bovine ciliary body. The 28-kDa protein catalyzed decomposition of the hydrogen peroxide as well as organic hydroperoxides by reduced glutathione and seems to be a member of the glutathion peroxidase family.
authors.affiliation: Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia.
authors.forename: I V
authors.initials: IV
authors.lastname: Peshenko
authors.forename: V I
authors.initials: VI
authors.lastname: Novoselov
authors.forename: V A
authors.initials: VA
authors.lastname: Evdokimov
authors.lastname: Nikolaev YuV
authors.forename: T M
authors.initials: TM
authors.lastname: Shuvaeva
authors.forename: V M
authors.initials: VM
authors.lastname: Lipkin
authors.forename: E E
authors.initials: EE
authors.lastname: Fesenko
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000906:Antibodies; D002417:Cattle; D002850:Chromatography, Gel; D004591:Electrophoresis, Polyacrylamide Gel; D004848:Epithelium / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000096:biosynthesis* / Q000737:chemistry / Q000302:isolation & purification; D007527:Isoenzymes / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D008715:Methionine / Q000378:metabolism; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009831:Olfactory Mucosa / Q000378:metabolism*; D009928:Organ Specificity; D011817:Rabbits / Q000276:immunology; D051381:Rats; D017386:Sequence Homology, Amino Acid; D013462:Sulfur Radioisotopes
chemical_list: D000906:Antibodies; D007527:Isoenzymes; D013462:Sulfur Radioisotopes; D008715:Methionine; D005979:Glutathione Peroxidase