title: A double-blind, randomized, placebo-controlled, multi-center study of brofaromine in the treatment of post-traumatic stress disorder.
abstract: A large multi-center, double-blind, parallel trial to assess the efficacy of brofaromine in the treatment of post traumatic stress disorder (PTSD) failed to show a significant difference between the brofaromine and placebo treatment groups. The placebo response rate in this study was higher than that in previously published double-blind, placebo-controlled studies of PTSD.
authors.affiliation: VA Medical Center, Cincinnati, Ohio, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Baker
authors.forename: B I
authors.initials: BI
authors.lastname: Diamond
authors.forename: G
authors.initials: G
authors.lastname: Gillette
authors.forename: M
authors.initials: M
authors.lastname: Hamner
authors.forename: D
authors.initials: D
authors.lastname: Katzelnick
authors.forename: T
authors.initials: T
authors.lastname: Keller
authors.forename: T A
authors.initials: TA
authors.lastname: Mellman
authors.forename: E
authors.initials: E
authors.lastname: Pontius
authors.forename: M
authors.initials: M
authors.lastname: Rosenthal
authors.forename: P
authors.initials: P
authors.lastname: Tucker
mesh_terms: D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D010880:Piperidines / Q000009:adverse effects / Q000627:therapeutic use*; D013313:Stress Disorders, Post-Traumatic / Q000188:drug therapy*
chemical_list: D008996:Monoamine Oxidase Inhibitors; D010880:Piperidines; C038213:brofaromine