title: The use of recombinant DNA technology in the design of a highly specific heroin sensor.
authors.affiliation: Institute of Biotechnology, University of Cambridge, United Kingdom.
authors.forename: D A
authors.initials: DA
authors.lastname: Rathbone
authors.forename: P J
authors.initials: PJ
authors.lastname: Holt
authors.forename: N C
authors.initials: NC
authors.lastname: Bruce
authors.forename: C R
authors.initials: CR
authors.lastname: Lowe
mesh_terms: D000115:Acetylesterase / Q000096:biosynthesis / Q000737:chemistry; D000595:Amino Acid Sequence; D000818:Animals; D015374:Biosensing Techniques; D002417:Cattle; D003001:Cloning, Molecular / Q000379:methods; D003124:Colorimetry / Q000379:methods; D016384:Consensus Sequence; D004274:DNA, Recombinant; D004950:Esterases / Q000737:chemistry; D003932:Heroin / Q000032:analysis* / Q000378:metabolism; D006556:Heroin Dependence / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D009016:Moraxella / Q000201:enzymology; D009020:Morphine / Q000032:analysis; D009022:Morphine Derivatives / Q000032:analysis; D011817:Rabbits; D051381:Rats; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry; D012240:Rhodococcus / Q000378:metabolism; D012680:Sensitivity and Specificity; D017386:Sequence Homology, Amino Acid; D013552:Swine; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D004274:DNA, Recombinant; D009022:Morphine Derivatives; D011994:Recombinant Proteins; D003932:Heroin; D009020:Morphine; D004950:Esterases; C022635:serine esterase; C090778:heroin esterase; D000115:Acetylesterase; C026979:6-O-monoacetylmorphine