title: The intergenerational predisposition to operative delivery.
abstract: OBJECTIVE
  To determine the risk of cesarean delivery for women who themselves were born via operative delivery.
  
  
  METHODS
  A linked data base was constructed between the birth certificates of individuals born in Utah during 1947-1957 (parental cohort) and who subsequently became a parent of offspring born in Utah between 1970-1991 (offspring cohort). Parental cohort women (cases) who had been delivered operatively (cesarean delivery, mid- or high forceps) as well as women who had a sibling delivered by an operative procedure were matched (1:2) with parental-cohort women born by spontaneous vaginal delivery (controls). Both cases and controls were selected based on having a record of at least one delivery in Utah during 1970-1991.
  
  
  RESULTS
  Women who were delivered by cesarean were at increased risk of subsequently delivering their children by cesarean (odds ratio [OR] 1.41, 95% confidence interval [CI] 1.18-1.70; P < .001). Progressive risk was associated with parental delivery by mid- or high forceps (OR 1.72, 95% CI 1.20-2.47; P = .004), parental cesarean because of cephalopelvic disproportion alone (OR 1.83, 95% CI 1.16-2.88; P = .01), or parental cesarean for dysfunctional labor (OR 5.97, 95% CI 1.5-23.6; P < .001). The attributable risk for cesarean delivery to the contemporary population is 3.5%.
  
  
  CONCLUSIONS
  An intergenerational predisposition to cesarean delivery exists.
authors.affiliation: Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, USA.
authors.forename: M W
authors.initials: MW
authors.lastname: Varner
authors.forename: A M
authors.initials: AM
authors.lastname: Fraser
authors.forename: C Y
authors.initials: CY
authors.lastname: Hunter
authors.forename: P S
authors.initials: PS
authors.lastname: Corneli
authors.forename: R H
authors.initials: RH
authors.lastname: Ward
mesh_terms: D002585:Cesarean Section / Q000706:statistics & numerical data; D015331:Cohort Studies; D016001:Confidence Intervals; D036861:Delivery, Obstetric; D004420:Dystocia / Q000235:genetics; D005113:Extraction, Obstetrical; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D007744:Obstetric Labor Complications; D016017:Odds Ratio; D011247:Pregnancy; D012307:Risk Factors