title: Effects of endotoxin on lipid metabolism.
abstract: Endotoxin, via cytokines, induces marked changes in lipid metabolism which are now considered part of the acute phase response. The endotoxin induced hyperlipidemia may represent a nonspecific immune response that can decrease the toxicity of a variety of harmful biological and chemical agents and serve to redistribute nutrients to cells important in host defense. The endotoxin induced changes in lipid metabolism may therefore be beneficial.
authors.affiliation: Department of Medicine, University of California San Francisco, USA.
authors.forename: I
authors.initials: I
authors.lastname: Hardardóttir
authors.forename: C
authors.initials: C
authors.lastname: Grunfeld
authors.forename: K R
authors.initials: KR
authors.lastname: Feingold
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D004731:Endotoxins / Q000378:metabolism / Q000633:toxicity*; D006801:Humans; D007239:Infections / Q000378:metabolism; D050356:Lipid Metabolism; D008074:Lipoproteins / Q000378:metabolism; D008075:Lipoproteins, HDL / Q000378:metabolism; D010272:Parasitic Diseases / Q000378:metabolism; D014280:Triglycerides / Q000378:metabolism; D014777:Virus Diseases / Q000378:metabolism
chemical_list: D004731:Endotoxins; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D014280:Triglycerides; D002784:Cholesterol