A ROC study of AMBER and conventional chest imaging in the detection of simulated interstitial lung disease.
OBJECTIVE
The aim of this study was to compare the detection of simulated interstitial lung disease with Advanced Multiple Beam Equalization Radiography (AMBER) and conventional wide latitude screen-film radiography.


METHODS
Interstitial disease of varying severity was simulated with overlays on an anthropomorphic chest phantom. A total of 60 images per modality was used in a Receiver Operating Characteristic (ROC) study.


RESULTS
AMBER performed significantly better than conventional radiography for all readers (P < 0.02). The difference was even more significant for the radiologist readers (P = 0.001). In each case the difference in ROC areas was between 5% and 9%.


CONCLUSIONS
AMBER is superior to conventional wide latitude screen-film imaging in detecting the subtle patterns used to simulate interstitial lung disease.
van Schelven
I H
IH
Department of Radiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
Winter
L H
LH
Chakraborty
D P
DP
Schultze Kool
L J
LJ
D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008953:Models, Anatomic; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging*; D012372:ROC Curve; D011856:Radiographic Image Enhancement / Q000295:instrumentation*; D014963:X-Ray Intensifying Screens