A neutrophilic drug reaction to Clomid.
A 33-year-old woman treated for infertility with multiple courses of clomiphene citrate (Clomid) presented with the complaint of a rash with every course of the medication. Examination revealed petechiae and palpable purpura on her lower extremities which, histologically, were found to be consistent with a neutrophilic drug reaction. The clinical course of this unusual presentation, as well as a brief review of the neutrophilic dermatoses, are provided.
Coots
N V
NV
Department of Obstetrics and Gynecology, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA.
McCoy
C E
CE
Gehlbach
D L
DL
Becker
L E
LE
D000328:Adult; D002996:Clomiphene / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects*; D006801:Humans; D009504:Neutrophils / Q000473:pathology*
D005300:Fertility Agents, Female; D002996:Clomiphene