Use of cysteine replacements and chemical modification to alter XIP, the autoinhibitory region of the Na-Ca exchanger. Inhibition of the activated plasma membrane Ca pump.
Xu
W Y
WY
Department of Physiology, University of Missouri, Columbia 65212, USA.
Gatto
C
C
Allen
C J
CJ
Milanick
M A
MA
D000595:Amino Acid Sequence; D002118:Calcium / Q000378:metabolism; D000252:Calcium-Transporting ATPases / Q000037:antagonists & inhibitors*; D002352:Carrier Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D002462:Cell Membrane / Q000378:metabolism; D003545:Cysteine; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry* / Q000494:pharmacology; D012964:Sodium / Q000378:metabolism; D019831:Sodium-Calcium Exchanger; D013329:Structure-Activity Relationship
D002352:Carrier Proteins; D010446:Peptide Fragments; D010455:Peptides; D019831:Sodium-Calcium Exchanger; C066745:exchanger inhibitory peptide; D012964:Sodium; D000252:Calcium-Transporting ATPases; D003545:Cysteine; D002118:Calcium