Multimodal management of diffuse neonatal hemangiomatosis.
Diffuse neonatal hemangiomatosis is a rare, frequently fatal disorder. We describe the case of a neonate with numerous cutaneous and ocular hemangiomas. Hepatic hemangiomas were noted at 4 weeks of age, associated with congestive heart failure resulting from hepatic arteriovenous shunting. This condition was controlled by treatment with prednisone, interferon alfa-2b and hepatic embolization. Treatment of cutaneous hemangiomas with the tunable dye laser prevented hemorrhage, facilitated routine skin care, and allowed uninhibited intravenous access during hospitalization.
Stratte
E G
EG
Department of Dermatology, Oregon Health Sciences University, Portland, USA.
Tope
W D
WD
Johnson
C L
CL
Swanson
N A
NA
D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006333:Heart Failure / Q000209:etiology; D006391:Hemangioma / Q000150:complications / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D015811:Iris Neoplasms / Q000628:therapy*; D017075:Laser Coagulation; D008113:Liver Neoplasms / Q000150:complications / Q000628:therapy*; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000628:therapy*; D011241:Prednisone / Q000627:therapeutic use; D011994:Recombinant Proteins; D012164:Retinal Diseases / Q000628:therapy*; D012878:Skin Neoplasms / Q000628:therapy*
D000970:Antineoplastic Agents; D005938:Glucocorticoids; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011241:Prednisone