title: [Genotype of hepatitis C virus in hemophiliacs].
abstract: Testing of blood sera of 63 hemophiliacs revealed markers of hepatitides B and C in 97 and 98% cases, respectively. Polymerase chain reaction confirmed the presence of hepatitis C virus (HCV) RNA in 31 (94%) out of 33 sera tested which contained antibodies to HCV. Gene typing of the isolated strains revealed the presence of three types of HCV: 1b (94%), 2a (3%), and 3a (3%). Similar distribution of HCV genotypes was revealed in the blood sera of 39 patients with chronic hepatitis C.
authors.forename: S N
authors.initials: SN
authors.lastname: Kuzin
authors.forename: L A
authors.initials: LA
authors.lastname: Mazhul'
authors.forename: I B
authors.initials: IB
authors.lastname: Snegireva
authors.forename: O P
authors.initials: OP
authors.lastname: Pliushts
authors.forename: I P
authors.initials: IP
authors.lastname: Gorbarets
authors.forename: I V
authors.initials: IV
authors.lastname: Shakhgil'dian
authors.forename: S O
authors.initials: SO
authors.lastname: Viazov
mesh_terms: D002908:Chronic Disease; D005838:Genotype; D006467:Hemophilia A / Q000150:complications*; D016174:Hepacivirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006526:Hepatitis C / Q000150:complications*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000097:blood
chemical_list: D018937:Hepatitis C Antibodies; D012367:RNA, Viral
vernacular_title: Genotipy virusa gepatita C u bol'nykh gemofilieĭ.