Antidepressant treatment of binge-eating disorder: research findings and clinical guidelines.
Binge-eating disorder, characterized by recurrent eating binges without purging, affects a large number of individuals, especially among participants in weight loss programs. Recent studies have suggested that antidepressants, particularly serotonin selective reuptake inhibitors, may be effective in the treatment of binge-eating disorder. This paper reviews the findings of these studies and offers clinical guidelines for the use of antidepressants in binge-eating disorder.
Hudson
J I
JI
Biological Psychiatry Laboratory, McLean Hospital, Belmont, Mass 02178, USA.
Carter
W P
WP
Pope
H G
HG
D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D001835:Body Weight / Q000187:drug effects; D002032:Bulimia / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology; D002986:Clinical Trials as Topic; D015897:Comorbidity; D003866:Depressive Disorder / Q000188:drug therapy / Q000453:epidemiology; D004334:Drug Administration Schedule; D001068:Feeding and Eating Disorders / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D009626:Terminology as Topic; D016896:Treatment Outcome
D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors