title: Engineered RNA-mediated resistance to tomato spotted wilt virus is sequence specific.
abstract: Transgenic plants were produced that expressed a wide range of randomly chosen sequences of the tripartite tomato spotted wilt virus (TSWV) RNA genome or its complement. Testing the progenies of these plants revealed that only transgenic expression of N or NS(M) gene sequences resulted in resistance to TSWV.
authors.affiliation: Department of Virology, Wageningen Agricultural University, Wageningen; The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Prins
authors.forename: R de O
authors.initials: Rde O
authors.lastname: Resende
authors.forename: C
authors.initials: C
authors.lastname: Anker
authors.forename: A
authors.initials: A
authors.lastname: van Schepen
authors.forename: P
authors.initials: P
authors.lastname: de Haan
authors.forename: R
authors.initials: R
authors.lastname: Goldbach
mesh_terms: D002213:Capsid / Q000096:biosynthesis; D016679:Genome, Viral; D007113:Immunity, Innate; D018551:Solanum lycopersicum / Q000235:genetics / Q000821:virology*; D010935:Plant Diseases; D010942:Plant Viruses / Q000235:genetics* / Q000472:pathogenicity*; D030821:Plants, Genetically Modified; D010947:Plants, Toxic; D012328:RNA Viruses / Q000235:genetics / Q000472:pathogenicity; D012367:RNA, Viral / Q000096:biosynthesis*; D014026:Nicotiana; D014158:Transcription, Genetic; D014758:Viral Core Proteins / Q000096:biosynthesis; D017361:Viral Nonstructural Proteins / Q000096:biosynthesis
chemical_list: D012367:RNA, Viral; D014758:Viral Core Proteins; D017361:Viral Nonstructural Proteins