title: Orthopedic aspects of myelodysplasia in children.
abstract: A review of new developments in spina bifida shows that many cases are preventable by administration of periconceptual folic acid, reducing the relative risk by up to 86%. Currently, however, 50% of women of reproductive age have no folic acid in their usual diet. The Centers for Disease Control as recommended folic acid at 0.4 mg/d for all women anticipating pregnancy. The long-term outcomes of sacral level patients show a surprising decline in adult ambulatory status. Adult ambulatory status in spina bifida is significantly predictive (89% accurate) by two variables: motor level and sitting balance. Studies regarding hip dislocation, foot deformities in thoracic level children, the prevalence of spondylolisthesis, and surgical treatment of kyphosis are also reviewed.
authors.affiliation: Northwestern University Medical School, Chicago, IL, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: Locke
authors.forename: J F
authors.initials: JF
authors.lastname: Sarwark
mesh_terms: D002648:Child; D005492:Folic Acid / Q000627:therapeutic use; D006397:Hematinics / Q000627:therapeutic use; D006801:Humans; D007738:Kyphosis / Q000503:physiopathology / Q000517:prevention & control; D008591:Meningomyelocele / Q000503:physiopathology / Q000517:prevention & control; D009436:Neural Tube Defects / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy; D011379:Prognosis; D016135:Spinal Dysraphism / Q000503:physiopathology / Q000517:prevention & control
chemical_list: D006397:Hematinics; D005492:Folic Acid