Sequence and neuronal expression of mouse endothelin-1 cDNA.
We have isolated and sequenced a cDNA that encodes mouse endothelin-1 (ET-1). The putative protein contains 202 amino acids corresponds to the prepro-form of ET-1. Twenty-one amino acids sequence of the putative mature ET-1 was identical with that of rat, porcine, bovine, and human. In situ hybridization histochemistry indicate that ET-1 mRNA was expressed in several hypothalamic nuclei including the suprachiasmatic nucleus (SCN) in rodent brain.
Kurama
M
M
National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ibaraki, Japan.
Ishida
N
N
Matsui
M
M
Saida
K
K
Mitsui
Y
Y
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D018076:DNA, Complementary / Q000737:chemistry*; D016232:Endothelins / Q000235:genetics*; D006801:Humans; D017403:In Situ Hybridization; D051379:Mice; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000032:analysis; D051381:Rats; D013493:Suprachiasmatic Nucleus / Q000378:metabolism*; D013552:Swine
D018076:DNA, Complementary; D016232:Endothelins; D012333:RNA, Messenger