title: [Pulmonary typical carcinoid with metastases to pulmonary hilar, and mediastinal lymph nodes].
abstract: A 50-year-old woman was admitted to our hospital complaining of recurrent bloody sputum and hemoptysis. Chest X-ray films showed an infiltrative shadow in the left lower lung field. Chest computed tomograms showed a nodular tumor shadow near the left B8 and this tumor shadow was found between A8 and A9 by pulmonary arteriography. Bronchoscopic examination revealed a red coagulum in the left B8 and cytologic examination of broncho alveolar lavage fluid revealed atypical squamous cells. With a clinical diagnosis of squamous cell carcinoma of the lung, a left lower lobectomy with hilar and mediastinal lymph node dissection was done. A milk-white tumor was found in the lower lobe of the resected lung. The pathological diagnosis of the resected tissue specimen was carcinoid, accompanied by pulmonary, hilar, and mediastinal lymph node metastases. Reduced immunofluorescence by Chromogranin A and serotonin staining were further evidence that the tumor was atypical. This case is very interesting in that the tumor metastasized to the lung and lymph nodes, even-though it was pathologically typical.
authors.affiliation: First Department of Internal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Momoki
authors.forename: I
authors.initials: I
authors.lastname: Fukushima
authors.forename: T
authors.initials: T
authors.lastname: Hoshi
authors.forename: S
authors.initials: S
authors.lastname: Kato
authors.forename: I
authors.initials: I
authors.lastname: Kishiro
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Hase
authors.forename: H
authors.initials: H
authors.lastname: Kuga
authors.forename: T
authors.initials: T
authors.lastname: Nakamoto
authors.forename: M
authors.initials: M
authors.lastname: Iizuka
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Nagai
authors.forename: K
authors.initials: K
authors.lastname: Shimada
mesh_terms: D002276:Carcinoid Tumor / Q000473:pathology*; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008482:Mediastinum; D008875:Middle Aged; D009362:Neoplasm Metastasis