Biological effects of hesperidin, a Citrus flavonoid. (Note III): antihypertensive and diuretic activity in rat.
Hesperidin, the most important flavanone of Citrus sp., obtained from the solid residue of orange peel, showed antihypertensive and diuretic effects on normotensive rats and on spontaneously hypertensive rats (SHR).
Galati
E M
EM
Dipartimento Farmaco-Biologico, Facoltà di Farmacia, Messina, Italia.
Trovato
A
A
Kirjavainen
S
S
Forestieri
A M
AM
Rossitto
A
A
Monforte
M T
MT
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D004231:Diuresis / Q000187:drug effects; D004232:Diuretics / Q000494:pharmacology*; D006569:Hesperidin / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011918:Rats, Inbred SHR; D017208:Rats, Wistar
D000959:Antihypertensive Agents; D004232:Diuretics; D006569:Hesperidin