[Incidence and risk factors of second primary cancers in patients treated for primary pharyngeal cancer].
About 13% of patients treated for a pharyngeal cancer suffer from a second primary cancer. Excessive consumptions of tobacco and/or alcohol are recognized as risk factors of second primary cancers in these patients. Epidemiologic studies suggest that antioxidant vitamins could have a protective effect on the occurrence of second primary cancers; however, this hypothesis should be confirmed by randomized clinical trials. A better knowledge of the risk factors of second primary cancers in patients with a pharyngeal cancer could help reducing the occurrence of second primary cancers and improving the follow-up of these patients.
Brochet
F
F
Hôpital de Chicoutimi, Saint-Vallier, Canada.
Bairati
I
I
Roy
J
J
Gélinas
M
M
Nabid
A
A
Têtu
B
B
Mâsse
B
B
Meyer
F
F
D002170:Canada / Q000453:epidemiology; D006258:Head and Neck Neoplasms / Q000453:epidemiology / Q000556:secondary*; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology / Q000556:secondary*; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D010610:Pharyngeal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D012042:Registries; D012307:Risk Factors; D014801:Vitamin A / Q000097:blood; D014810:Vitamin E / Q000097:blood
D014801:Vitamin A; D014810:Vitamin E
Incidence et facteurs de risque de seconds cancers primaires chez les patients traités pour un premier cancer du pharynx.