[A case of hepatocellular carcinoma responding to oral administration of 5'-DFUR].
A 65-year-old female patient with liver cirrhosis complicated with hepatocellular carcinoma (HCC) was treated with oral administration of 5'-DFUR (600 mg/day). The titer of serum alpha-fetoprotein gradually decreased, and reduction of the hepatic tumor size was observed by abdominal computed tomography (CT) following 5'-DFUR treatment. HCC was obviously diminished since the start of 5'-DFUR administration and almost disappeared in fifteen months. This case suggests the treatment with 5'-DFUR for hepatocellular carcinoma is completely effective.
Tanaka
Y
Y
Dept. of Gastroenterology, Nagoya Daini Red Cross Hospital, Japan.
Ogino
M
M
Tokuda
H
H
Mizuno
M
M
Yamauchi
M
M
D000284:Administration, Oral; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D005260:Female; D005467:Floxuridine / Q000008:administration & dosage*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D012074:Remission Induction; D000509:alpha-Fetoproteins / Q000378:metabolism
D000970:Antineoplastic Agents; D000509:alpha-Fetoproteins; D005467:Floxuridine; C025034:doxifluridine