title: Seroepidemiological and leishmanin skin test surveys of visceral leishmaniasis in south and southwest Ethiopia.
abstract: Sero-epidemiological and leishmanin skin test surveys of visceral leishmaniasis were carried out in eight localities of South and Southwest Ethiopia between the July 1989 and June 1992. A total number of 4870 subjects comprising semi-pastoral nomads, peasants and farm labourers were included in the study. Areas of high and low leishmanin skin test positivity were identified, with rates varying from 1.0-80.5%. An enzyme-linked immunosorbent assay was used to determine prevalence of antileishmanial antibodies. The rates varied from 1.8% to 27.8%. Age and sex related serological and leishmanin skin test profiles are described. Correlation analysis of serological and leishmanin skin test was made for data in each locality. The relationships between seroprevalence, leishmanin skin test rates and prevalence of active visceral leishmaniasis and the implications on degrees of endemicity and patterns of transmission are discussed.
authors.affiliation: Institute of Pathobiology, Addis Abeba University, Addis Abeba, Ethiopia.
authors.forename: A
authors.initials: A
authors.lastname: Hailu
authors.forename: N
authors.initials: N
authors.lastname: Berhe
authors.forename: Z
authors.initials: Z
authors.lastname: Sisay
authors.forename: I
authors.initials: I
authors.lastname: Abraham
authors.forename: G
authors.initials: G
authors.lastname: Medhin
mesh_terms: D000293:Adolescent; D000328:Adult; D000953:Antigens, Protozoan; D002648:Child; D002675:Child, Preschool; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D007898:Leishmaniasis, Visceral / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012423:Rural Health; D016036:Seroepidemiologic Studies; D012882:Skin Tests
chemical_list: D000953:Antigens, Protozoan; C032127:leishmanin