Erythropoietin treatment of erythropoietin-deficient anemia without renal disease during pregnancy.
BACKGROUND
The use of recombinant human erythropoietin in pregnancy has been described in patients with renal impairment. We present a patient with a hypoproliferative anemia with low serum erythropoietin levels and no renal disease or other known cause for this type of anemia, who was treated with recombinant human erythropoietin.


METHODS
A 29-year-old white woman who became pregnant after leuprolide acetate and menopausal gonadotropin therapy developed a moderate anemia (hemoglobin 8.5 g/dL) in early pregnancy. The only important laboratory findings were a hypoproliferative marrow and a low serum erythropoietin level. She was treated successfully with injections of recombinant human erythropoietin. Her pregnancy was otherwise uncomplicated and her pre-delivery hemoglobin level was 12 g/dL.


CONCLUSIONS
Hypoproliferative anemia in pregnancy with low erythropoietin levels and no renal disease can be treated successfully with recombinant human erythropoietin.
Harris
S A
SA
Division of Maternal-Fetal Medicine, Baylor University Medical Center, Dallas, Texas, USA.
Payne
G
G
Putman
J M
JM
D000328:Adult; D000740:Anemia / Q000188:drug therapy*; D004921:Erythropoietin / Q000172:deficiency* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007674:Kidney Diseases; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011256:Pregnancy Outcome; D011994:Recombinant Proteins / Q000627:therapeutic use
D011994:Recombinant Proteins; D004921:Erythropoietin