[MR-mammography assessment of tumor response after neoadjuvant radiochemotherapy of locally advanced breast carcinoma].
OBJECTIVE
We investigated the role of magnetic resonance mammography in monitoring tumour response of locally advanced breast cancer (LABC) after neoadjuvant radiochemotherapy.


METHODS
17 patients with LABS had a magnetic resonance mammography and ultrasonography before and after neoadjuvant radiochemotherapy.


RESULTS
After neoadjuvant radiochemotherapy 14 patients showed in MR-mammography less pronounced and prolonged enhancement without washout. After treatment three patients had signal intensity-time curves still characteristic for tumour. Ultrasonography was true negative in two patients, true positive in 12 and false positive in three patients.


CONCLUSIONS
Magnetic resonance mammography is suitable for monitoring tumour response after radiochemotherapy of LABC. However, a negative MRI does not exclude a residual tumour. Ultrasonography is of limited value in monitoring therapy of LABC.
Kurtz
B
B
Radiologische Klinik, Evangelischen Krankenhauses Düsseldorf.
Achten
C
C
Audretsch
W
W
Rezai
M
M
Urban
P
P
Zocholl
G
G
D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D018275:Carcinoma, Lobular / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D014463:Ultrasonography
MR-mammographische Beurteilung des Tumoransprechverhaltens nach neoadjuvanter Radiochemotherapie lokal fortgeschrittener Mammakarzinome.