[Effect of essentiale on the cardioprotective action of anapriline, nitroglycerin and their combinations in acute total myocardial ischemia].
The pattern of changes in myocardial energy metabolism and antioxidative enzyme activities was examined in acute total myocardial ischemia treated with anapriline, nitroglycerin, and essentiale. There was an increase and prolongation of the metabolic effects and activity of antianginal agents along with the animal saturation with polyunsaturated phospholipids. In early and late acute total myocardial ischemia, the most pronounced effect was observed during administration of a combination of anapriline, nitroglycerin, and essentiale.
Bender
K I
KI
Zakharova
N B
NB
Verizhnikova
E V
EV
D000818:Animals; D004359:Drug Therapy, Combination; D005260:Female; D017202:Myocardial Ischemia / Q000188:drug therapy*; D005996:Nitroglycerin / Q000627:therapeutic use*; D010713:Phosphatidylcholines / Q000627:therapeutic use*; D011433:Propranolol / Q000627:therapeutic use*; D051381:Rats
D010713:Phosphatidylcholines; C011246:essential 303 forte; D011433:Propranolol; D005996:Nitroglycerin
Vliianie éssentiale na kardioprotektornoe deĭstvie anaprilina, nitroglitserina i ikh sochetaniia pri ostroĭ total'noĭ ishemii miokarda.