title: [Functional MRI of the pharynx in obstructive sleep apnea using rapid 2D FLASH sequences].
abstract: Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager ("Vision", Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and polysomnography. A temporal resolution of 6 images/s and an in-plane resolution of 2.67 x 1.8 mm were achieved. The mobility of the tongue, soft palate and pharyngeal surface could be clearly delineated. The MRI findings correlated well with the clinical examinations. We propose ultrafast MRI as a reliable and non-invasive method of evaluating pharyngeal obstruction and their levels.
authors.affiliation: Institut für Radiologische Diagnostik, Klinikum Grosshadern der Ludwig-Maximilians-Universität München.
authors.forename: L
authors.initials: L
authors.lastname: Jäger
authors.forename: E
authors.initials: E
authors.lastname: Günther
authors.forename: J
authors.initials: J
authors.lastname: Gauger
authors.forename: W
authors.initials: W
authors.lastname: Nitz
authors.forename: E
authors.initials: E
authors.lastname: Kastenbauer
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D019028:Magnetic Resonance Imaging, Cine / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D010160:Palate, Soft / Q000473:pathology / Q000503:physiopathology; D010614:Pharynx / Q000473:pathology / Q000503:physiopathology*; D012891:Sleep Apnea Syndromes / Q000175:diagnosis* / Q000503:physiopathology; D012913:Snoring / Q000503:physiopathology; D014059:Tongue / Q000473:pathology / Q000503:physiopathology
vernacular_title: Funktionelle MRT des Pharynx bei obstruktiver Schlafapnoe (OSA) mit schnellen 2D-FLASH-Sequenzen.