Response of Egyptian infants with protein calorie malnutrition to hepatitis B vaccination.
The response to recombinant hepatitis B vaccine was assessed in 31 seronegative infants (2-26 months old) with protein calorie malnutrition (PCM), compared with 13 seronegative age- and sex-matched healthy infants. Both groups received three 10 micrograms vaccine doses at 0, 1, and 6 months. At month 8, all healthy infants and 87 per cent (27 out of 31) of PCM infants were seroprotected. Thus, hepatitis B vaccination (Engerix-B, SmithKline Beecham Biologicals) can be used effectively in PCM for mass vaccination in developing communities.
el-Gamal
Y
Y
Pediatric Department of Ain Shams University, Cairo, Egypt.
Aly
R H
RH
Hossny
E
E
Afify
E
E
el-Taliawy
D
D
D002675:Child, Preschool; D003906:Developing Countries; D004534:Egypt; D005260:Female; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000096:biosynthesis*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage / Q000276:immunology; D006801:Humans; D007115:Immunization Schedule; D007223:Infant; D008297:Male; D011502:Protein-Energy Malnutrition / Q000276:immunology*; D014611:Vaccination
D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines