[Study of comparative immunity of patients with M. tuberculosis and atypical Mycobacteria infection and infection by human immunodeficiency virus (HIV)].
The purpose of this retrospective study was to determine the basal immune status, in patients with human immunodeficiency virus (HIV) infection, who were affected from tuberculosis (TB) caused by Mycobacterium tuberculosis or atypical mycobacterium. In the current study, we report our experience with 280 patients diagnosed TB and HIV: fifty cases were eligible for enrollment at random with M. tuberculosis (group I) and we compare with 23 cases of atypical mycobacterias (group 2). When we analyze statistically both groups, we detected in group 2 the existence of a CD4 Lymphocytes count decrease and a mean IgA raised, opposite to group I (P < 0.0001). On other side, our investigation on survival showed that this was lower in atypical mycobacterias group (group 2) with a median time of survival of 10 months, opposite to 2,9 years in group I.
Navarro
V
V
Servicio de Medicina Interna, Hospital General Alicant.
Guix
J
J
Roig
P
P
Borras
R
R
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000276:immunology; D015704:CD4 Antigens / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D015658:HIV Infections / Q000150:complications* / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007136:Immunoglobulins / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000276:immunology*; D012189:Retrospective Studies; D012307:Risk Factors; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000276:immunology*
D015704:CD4 Antigens; D007136:Immunoglobulins
Estudio de inmunidad comparativo entre pacientes con infección por M. tuberculosis y micobacterias atípicas que están infectados por el virus de la inmunodeficiencia humana (VIH).