Benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine: biological activities and dental care applications.
This article reviews chemical, pharmacological, and toxicological research relating to two principal benzo[c]phenanthridine alkaloids, namely sanguinarine and chelerythrine, in the period 1980-1994. The medical applications of these alkaloids in relation to their biological activities are discussed.
Walterová
D
D
Institute of Medical Chemistry, Faculty of Medicine, Palacký University Olomouc, Czech Republic.
Ulrichová
J
J
Válka
I
I
Vicar
J
J
Vavrecková
C
C
Táborská
E
E
Harjrader
R J
RJ
Meyer
D L
DL
Cerná
H
H
Simánek
V
V
D000470:Alkaloids / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D053119:Benzophenanthridines; D006801:Humans; D007546:Isoquinolines; D009067:Mouthwashes / Q000494:pharmacology / Q000627:therapeutic use; D009910:Oral Hygiene; D010617:Phenanthridines / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use
D000470:Alkaloids; D053119:Benzophenanthridines; D007546:Isoquinolines; D009067:Mouthwashes; D010617:Phenanthridines; C005705:sanguinarine; C016299:chelerythrine