ARF-regulated phospholipase D: a potential role in membrane traffic.
Phospholipase D activity is stimulated rapidly upon occupation of cell-surface receptors. One of the intracellular regulators of phospholipase D activity has been identified as ADP ribosylation factor (ARF). ARF is a small GTP binding protein whose function has been elucidated in vesicular traffic. This review puts into context the connection between the two fields of signal transduction and vesicular transport.
Cockcroft
S
S
Department of Physiology, University College London, UK. ucgbsxc@ucl.ac.uk
D020727:ADP-Ribosylation Factors; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000502:physiology*; D006801:Humans; D010739:Phospholipase D / Q000378:metabolism*
D010739:Phospholipase D; D019204:GTP-Binding Proteins; D020727:ADP-Ribosylation Factors