Imaging of olfactory neuroblastoma by In-111 bleomycin complex.
No other successful nuclear method, besides bone scanning, has been reported in the literature for in vivo imaging of olfactory neuroblastoma. In this article, excellent uptake is reported by an In-111 labeled bleomycin complex (BLMC) in the ethmoid region of a histologically confirmed olfactory neuroblastoma. The uptake of BLMC was 0.7 x 10(-3)% ID/g at 48 hours after injection, and tumor-to-muscle and tumor-to-fat ratios were 6:1 and 11:1, respectively. The authors conclude that BLMC should be considered as a useful imaging agent, and the BLMC has potential as a radiochemotherapeutic agent against an olfactory neuroblastoma.
Jekunen
A P
AP
Department of Oncology, Helsinki University Central Hospital, Finland.
Kairemo
K J
KJ
Ramsay
H A
HA
Kajanti
M J
MJ
D000368:Aged; D001761:Bleomycin / Q000031:analogs & derivatives*; D018304:Esthesioneuroblastoma, Olfactory / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D009296:Nasal Cavity / Q000000981:diagnostic imaging*; D009669:Nose Neoplasms / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D011877:Radionuclide Imaging; D013997:Time Factors
D007205:Indium Radioisotopes; D009942:Organometallic Compounds; C047120:indium-bleomycin; D001761:Bleomycin