Plasma fibronectin kinetics during uncomplicated acute myocardial infarction.
Plasma fibronectin (Fbn) was assessed daily in 9 men admitted to the cardiology care unit for uncomplicated acute myocardial infarction (AMI). In a control group of twenty healthy men, plasma Fbn was 0.290 +/- 0.0417 g/l-1 (mean +/- SD). In 6 hypertensive AMI patients, Fbn levels were increased to a maximum of 0.461 +/- 0.0294 g/l-1 at day five (5.5 +/- 0.84 days) and returned to the range of the control group values 56 +/- 32.8 hours afterwards. Three normotensive patients had higher Fbn results without returning to the control group range at the end of the hospitalization (0.734 +/- 0.0209 gl-1). Plasma Fbn could in part be implicated in the repair process and/or in the limitation of the cardiac necrosis extension. Moreover, it seems that a link exists between plasma Fbn kinetics and hypertension and/or normotension during uncomplicated AMI.
Laudat
A
A
Laboratoire de Biochimie et Service de Cardiologie, Centre Hospitalier Régional Universitaire, Guadeloupe.
Ano-Monfils
N
N
Haddad
A
A
Pileire
B
B
D000368:Aged; D016022:Case-Control Studies; D005353:Fibronectins / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000150:complications / Q000473:pathology; D009336:Necrosis; D013997:Time Factors
D005353:Fibronectins