Obstructive lung disease and sleep.
There is a significant interaction between obstructive lung disease and sleep--sleep is associated with clinical deterioration in obstructive lung disease, and vice versa. Knowledge of the pathophysiology of deterioration in obstructive lung disease during sleep is essential to the understanding of the management of this problem. Recent information has helped to clarify this pathophysiology and has led to more aggressive treatment for deterioration of obstructive lung disease during sleep. Whether this newer and more aggressive treatment strategy improves survival or morbidity in these conditions is a challenge for future research.
Jokic
R
R
Department of Medicine, University of Saskatchewan, Sasakatoon, Canada.
Fitzpatrick
M F
MF
D001249:Asthma / Q000503:physiopathology / Q000628:therapy; D003550:Cystic Fibrosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology* / Q000628:therapy; D012119:Respiration; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000503:physiopathology / Q000628:therapy