title: Malignant occipital astrocytoma in a patient with Lhermitte-Duclos disease (cerebellar dysplastic gangliocytoma).
abstract: A case of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) is described. Seventeen years after the diagnosis was made, the patient developed a malignant astrocytoma of the cerebrum, an association only once previously reported. The clinical presentation and radiological features are presented.
authors.affiliation: Department of Neurosurgery, Groote Schuur Hospital, University of Cape Town, South Africa.
authors.forename: Z
authors.initials: Z
authors.lastname: Domingo
authors.forename: N D
authors.initials: ND
authors.lastname: Fisher-Jeffes
authors.forename: J C
authors.initials: JC
authors.lastname: de Villiers
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology*; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000150:complications* / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D005260:Female; D005729:Ganglioneuroma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009778:Occipital Lobe / Q000473:pathology*; D014057:Tomography, X-Ray Computed