[Mucormycosis--a rare complication in patients with diabetes mellitus].
Mucormycosis usually occurs in immunocompromised patients or in patients with diabetes mellitus. Pathogens are moulds of the mucorales species. The diagnosis is made by histological examination of biopsies. A 39 year-old patient with insulin-dependent diabetes mellitus was admitted with a tentative diagnosis of a tumour of the maxilla. After diagnosis of hyphae of the mucorales species, the patient's diabetes was stabilised and he was treated over 17 weeks with amphotericin B (40 mg per day) and made a good recovery. A 58 year-old insulin-dependent patient with ethmoidali and sphenoidali sinusitis did not respond to antibiotic therapy. Mucormycosis was diagnosed by means of biopsy. Although treatment with amphotericin B was started, the patient died after 3 weeks due to multiple organ failure.
Robibaro
B
B
Abteilung für Infektionen und Chemotherapie, Universitätsklinik für Innere Medizin I, Wien.
Pammer
J
J
Leber
J
J
Knapp
S
S
Vorbach
H
H
Presterl
E
E
D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D001706:Biopsy; D003131:Combined Modality Therapy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D010256:Paranasal Sinuses / Q000473:pathology; D012852:Sinusitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D000935:Antifungal Agents; D000666:Amphotericin B
Mucormykose--Eine seltene Komplikation bei Patienten mit Diabetes mellitus.