title: Protamine reaction in a patient undergoing coronary artery bypass grafting.
abstract: The neutralization of heparin anticoagulation is accomplished by the administration of protamine. While the administration of protamine is generally uneventful, allergic reactions can occur. This article describes such a reaction in a patient having cardiac surgery. Classification of protamine reactions and signs and symptoms are discussed. Treatment and management of high risk patients is highlighted.
authors.forename: C
authors.initials: C
authors.lastname: Hughes
authors.forename: M
authors.initials: M
authors.lastname: Haddock
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass; D004342:Drug Hypersensitivity / Q000145:classification / Q000209:etiology* / Q000628:therapy; D005260:Female; D006494:Heparin Antagonists / Q000009:adverse effects*; D006801:Humans; D011479:Protamines / Q000009:adverse effects*
chemical_list: D006494:Heparin Antagonists; D011479:Protamines