[Clinical significance of gel electrophoresis of blood lipoproteins in primary biliary cirrhosis].
Gel electrophoresis was used for separation of lipoproteins of the blood sera in patients with primary biliary cirrhosis (PBC) of the liver and cholelithiasis. Increased level of beta-lipoproteins in parallel with a reduction of total alpha- and pre-beta-lipoproteins were revealed in patients with PBC, these shifts being more expressed at later stages of the disease. An appreciable increase of beta- to alpha-lipoprotein ratio in PBC was observed. In patients with cholelithiasis no shifts in the lipoprotein profile of the blood serum were observed. The authors claim that the beta- to alpha-lipoprotein ratio is diagnostically significant in chronic hepatobiliary diseases.
Loginov
A S
AS
Reshetniak
V I
VI
Chebanov
S M
SM
Matiushin
B N
BN
D000328:Adult; D002769:Cholelithiasis / Q000097:blood / Q000175:diagnosis; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004587:Electrophoresis, Agar Gel; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008105:Liver Cirrhosis, Biliary / Q000097:blood* / Q000175:diagnosis; D008875:Middle Aged
D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL
Klinicheskoe znachenie gel'-élektroforeza lipoproteidov syvorotki krovi pri pervichnom biliarnom tsirroze.