title: Lack of inhibition of phosphoinositide 3-kinase enzyme activity by FKBP12/rapamycin.
authors.affiliation: Astra Charnwood, Loughborough, Leics, U.K.
authors.forename: C M
authors.initials: CM
authors.lastname: Hollis
authors.forename: R
authors.initials: R
authors.lastname: Hutchinson
mesh_terms: D000730:Androstadienes / Q000494:pharmacology; D000818:Animals; D002352:Carrier Proteins / Q000494:pharmacology*; D002852:Chromatography, Ion Exchange; D003600:Cytosol / Q000201:enzymology; D004268:DNA-Binding Proteins / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006360:Heat-Shock Proteins / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism*; D011090:Polyenes / Q000494:pharmacology*; D051381:Rats; D020123:Sirolimus; D022021:Tacrolimus Binding Proteins; D000077191:Wortmannin
chemical_list: D000730:Androstadienes; D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D004791:Enzyme Inhibitors; D006360:Heat-Shock Proteins; D007166:Immunosuppressive Agents; D011090:Polyenes; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor); D022021:Tacrolimus Binding Proteins; D020123:Sirolimus; D000077191:Wortmannin