Pineal ganglioglioma with premature thelarche. Report of a case and review of the literature.
We report a case of a 6-year-old girl with a ganglioglioma in the pineal region presenting with a rare clinical picture of premature thelarche. Intracranial gangliogliomas are rare, especially in the pineal region. Their character, origin, treatment, and prognosis remain controversial. The pathophysiology of precocious puberty associated with pineal ganglioglioma is discussed.
Chang
Y L
YL
Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, R.O.C.
Lin
S Z
SZ
Chiang
Y H
YH
Liu
M Y
MY
Lee
W H
WH
D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology / Q000648:ultrastructure; D002648:Child; D005260:Female; D018303:Ganglioglioma / Q000150:complications* / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D010784:Photomicrography; D010870:Pineal Gland / Q000473:pathology* / Q000648:ultrastructure; D011629:Puberty, Precocious / Q000209:etiology*