First examples of peptidomimetic inhibitors of interleukin-1 beta converting enzyme.
Dolle
R E
RE
Sanofi Winthrop Inc., Collegeville, Pennsylvania 19426, USA.
Prouty
C P
CP
Prasad
C V
CV
Cook
E
E
Saha
A
A
Ross
T M
TM
Salvino
J M
JM
Helaszek
C T
CT
Ator
M A
MA
D000595:Amino Acid Sequence; D020170:Caspase 1; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D015853:Cysteine Proteinase Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015195:Drug Design; D006860:Hydrogen Bonding; D007375:Interleukin-1 / Q000378:metabolism; D007700:Kinetics; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000494:pharmacology; D011743:Pyrimidines / Q000138:chemical synthesis / Q000494:pharmacology
D015853:Cysteine Proteinase Inhibitors; D007375:Interleukin-1; D009842:Oligopeptides; D011743:Pyrimidines; D003546:Cysteine Endopeptidases; D020170:Caspase 1