title: Primary diaphragmatic schwannoma with a typical target appearance: correlation of CT and MR imagings and histologic findings.
abstract: A rare case of benign diaphragmatic schwannoma in a 38-year-old female is reported. Precontrast computed tomography (CT) showed an encapsulated well-defined round homogeneous tumor with central calcification, measuring approximately 5 cm in diameter, arising from the left diaphragm. Contrast-enhanced CT and gadolinium-enhanced T1-weighted magnetic resonance (MR) imaging showed focal enhancement in the central portion of the tumor. The tumor showed a typical target appearance of increased peripheral signal intensity and decreased central signal intensity on unenhanced T2-weighted images. Pathological examination of resected specimens of the tumor showed two zonal histological components: a hypercellular portion of spindle cells with nuclear palisading (Antoni A tissue) and a hypocellular portion of cells with cystic degeneration, together with focal calcification and hemangeomatous vascular changes (Antoni B tissue). We consider the radiological characteristics of diaphragmatic schwannoma on CT and MR imagings to represent the geographic difference between the histologic zones of the tumor.
authors.affiliation: Department of Internal Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Koyama
authors.forename: M
authors.initials: M
authors.lastname: Araki
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Fukutomi
authors.forename: T
authors.initials: T
authors.lastname: Maruyama
authors.forename: Y
authors.initials: Y
authors.lastname: Mun
authors.forename: M
authors.initials: M
authors.lastname: Otsuka
authors.forename: K
authors.initials: K
authors.lastname: Fukao
mesh_terms: D000328:Adult; D003964:Diaphragm / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009442:Neurilemmoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D012142:Respiratory Tract Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed