Recurrent priapism as a side effect of zuclopenthixol decanoate.
Priapism has been described as a rare side effect of certain phenothiazine antipsychotics with high alpha1-adrenergic blocking potential. We describe a patient who in the course of clinical treatment with the thioxanthene antipsychotic zuclopenthixol (Clopixol) decanoate had several episodes of priapism. Although the alpha-blocking potential of zuclopenthixol is only moderate, it seems that in sufficient dose, or in combination with other antipsychotics, this drug is capable of inducing priapism.
van Hemert
A M
AM
Psychiatric Hospital Bloemendaal, The Hague, The Netherlands.
Meinhardt
W
W
Moehadjir
D
D
Kropman
R F
RF
D000328:Adult; D003006:Clopenthixol / Q000009:adverse effects*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011317:Priapism / Q000139:chemically induced*; D012559:Schizophrenia / Q000188:drug therapy; D016896:Treatment Outcome
D003006:Clopenthixol