The G1691A mutation of the coagulation factor V gene (factor V Leiden) is rare in Chinese: an analysis of 618 individuals.
To understand the allele frequency of the G1691A mutation of the coagulation factor V gene (factor V Leiden) in Chinese, 618 Chinese individuals, including 54 cases with venous thrombosis, were analyzed. Only one case in the control group was heterozygous for the 1691G allele and the 1691A allele. Our data suggest that the factor V Leiden is rare in Chinese.
Ko
Y L
YL
Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
Hsu
T S
TS
Wu
S M
SM
Ko
Y S
YS
Chang
C J
CJ
Wang
S M
SM
Chen
W J
WJ
Cheng
N J
NJ
Kuo
C T
CT
Chiang
C W
CW
Lee
Y S
YS
D000483:Alleles; D016022:Case-Control Studies; D002681:China; D005165:Factor V / Q000235:genetics*; D005787:Gene Frequency; D006579:Heterozygote; D006801:Humans; D017354:Point Mutation; D011486:Protein C / Q000378:metabolism; D013924:Thrombophlebitis / Q000097:blood / Q000235:genetics
D011486:Protein C; C095381:factor V Leiden; D005165:Factor V