title: [A case of bronchiolo-alveolar carcinoma with high production of carbohydrate antigen (CA19-9)].
abstract: A 75-year-old female had loss of appetite, left hypochondrial and back pain. An X-ray and a computed tomogram of both lungs showed multiple small granular shadows. By Tc-labelled bone scintigram, multiple uptakes were found. Since high serum CA19-9 was obtained, pancreatic or bile duct cancer with multiple lung and bone metastasis was suspected. The autopsy revealed, small nodules in both lungs were well-differentiated adenocarcinoma, bronchiolo-alveolar type, and immunohistologically, tumor cells were stained positively for CA19-9. Since CA19-9 exists in normal bronchial glands and bronchiole, high level of serum CA19-9 in our patient may be derived from the neoplastic bronchiolar epithelium.
authors.affiliation: Department of Surgery, Okayama Saiseikai General Hospital, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shioji
authors.forename: Y
authors.initials: Y
authors.lastname: Akazai
authors.forename: T
authors.initials: T
authors.lastname: Takahata
authors.forename: Y
authors.initials: Y
authors.lastname: Okamoto
authors.forename: T
authors.initials: T
authors.lastname: Ohara
authors.forename: N
authors.initials: N
authors.lastname: Tsutsui
authors.forename: S
authors.initials: S
authors.lastname: Hirose
authors.forename: K
authors.initials: K
authors.lastname: Kataoka
mesh_terms: D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000276:immunology* / Q000473:pathology; D000368:Aged; D018395:CA-19-9 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology* / Q000473:pathology
chemical_list: D018395:CA-19-9 Antigen