title: [Evolution of viral hepatitis B markers in children infected with HBV in the first two years of life].
abstract: Circumstances of acquiring an infection, spontaneous evolution of markers during 6 years of follow-up, laboratory findings and results of liver biopsies were analysed in 51 children infected with HBV during the first two years of life; 76.5% of them developed chronic carrier state. ALAT values were periodically increased in 34 children (66.6%) and elimination of HBeAg i HBsAg occurred in 17 (33.3%) and 12 children (23.5%), respectively, during the first year of follow-up. Seroconversion was observed only in a few cases in the subsequent years. Anti-HBc IgM antibodies were detectable for a mean period of less than 7 months (p < 0.02) after diagnosis of infection.
authors.affiliation: Katedra i Klinika Chorób Dzieci Akademii Medycznej w Bydgoszcy.
authors.forename: J
authors.initials: J
authors.lastname: Styczyński
authors.forename: E
authors.initials: E
authors.lastname: Smukalska
authors.forename: M
authors.initials: M
authors.lastname: Dorau
mesh_terms: D002908:Chronic Disease; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology / Q000821:virology*; D006515:Hepatitis B virus / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011044:Poland / Q000453:epidemiology
vernacular_title: Ewolucja markerów wirusowego zapalenia watroby typu B u dzieci zakazonych w dwóch pierwszych latach zycia.