Pharmacological modulation of voltage-gated Na+ channels: a rational and effective strategy against ischemic brain damage.
Urenjak
J
J
Department of Neurological Surgery, Institute of Neurology, London, UK.
Obrenovitch
T P
TP
D000818:Animals; D001921:Brain / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D002545:Brain Ischemia / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control; D015220:Calcium Channels / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects / Q000378:metabolism; D015536:Down-Regulation; D004734:Energy Metabolism; D006706:Homeostasis; D006801:Humans; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D010766:Phosphorylation; D012530:Saxitoxin / Q000494:pharmacology / Q000627:therapeutic use; D012964:Sodium / Q000378:metabolism; D015222:Sodium Channels / Q000187:drug effects* / Q000378:metabolism; D013779:Tetrodotoxin / Q000494:pharmacology / Q000627:therapeutic use
D015220:Calcium Channels; D018696:Neuroprotective Agents; D015222:Sodium Channels; D012530:Saxitoxin; D013779:Tetrodotoxin; D012964:Sodium