title: [A case of the successful treatment of a patient with severe craniocerebral trauma combined with hemophilia].
abstract: The described case with a severe craniocerebral injury in a patient with hemophilia A demonstrated that the initial hypocoagulation does not preclude the development of intravascular blood coagulation. Therefore, in patients with severe brain injury, a more rapid reduction of antihemophilic globulin A is possible, in comparison with that occurring during planned surgery, and, hence, higher doses of cryoprecipitate and longer duration of its infusion are needed. Moreover, this case demonstrated that even in patients with a slight form of hemophilia A the treatment with cryoprecipitate should be continued till the levels of thrombinemia markers are reduced and the concentration of antihemophilic globulin A in the blood stabilized at a level of at least 10%; the dose of infused cryoprecipitate should be reduced gradually.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Churliaev
authors.forename: N N
authors.initials: NN
authors.lastname: Epifantseva
authors.forename: V S
authors.initials: VS
authors.lastname: Karpenko
authors.forename: D N
authors.initials: DN
authors.lastname: Chesnokov
authors.forename: A A
authors.initials: AA
authors.lastname: Pavlenko
authors.forename: N M
authors.initials: NM
authors.lastname: Rog
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000097:blood / Q000150:complications / Q000601:surgery*; D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology / Q000628:therapy; D004630:Emergencies; D006467:Hemophilia A / Q000097:blood / Q000150:complications* / Q000628:therapy; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D011182:Postoperative Care; D011183:Postoperative Complications / Q000097:blood / Q000209:etiology / Q000628:therapy
vernacular_title: Sluchaĭ uspeshnogo lecheniia bol'nogo s tiazheloĭ cherepno-mozgovoĭ travmoĭ v sochetanii s gemofilieĭ.