Effects of high-dose oral vitamin A on diarrheal episodes among children with persistent diarrhea in a northeast Brazilian community.
The mean +/- SEM duration of diarrheal episodes decreased from 7.1 +/- 2.2 days to 4.3 +/- 0.9 days (P < 0.05) while the incidence of diarrheal episodes remained steady (2.2 +/- 0.3 versus 2.4 +/- 0.5 episodes; P = not significant) between two three-month periods before and after the oral administration of a single large age-adjusted dose of vitamin A among children at historical risk for persistent diarrhea in an impoverished Brazilian community.
Walser
B L
BL
Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.
Lima
A A
AA
Guerrant
R L
RL
D000284:Administration, Oral; D001938:Brazil / Q000453:epidemiology; D003968:Diarrhea, Infantile / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D015994:Incidence; D007223:Infant; D008137:Longitudinal Studies; D012307:Risk Factors; D012621:Seasons; D013997:Time Factors; D014801:Vitamin A / Q000008:administration & dosage*
D014801:Vitamin A