End stage liver disease in a 13-year old secondary to hepatitis C and hemochromatosis.
Hepatic parenchymal iron deposition is a well-known complication of chronic hepatic inflammatory states. This can make the differential between chronic hepatitis and hereditary hemochromatosis difficult, however. The case of a 13-yr-old male with chronic hepatitis C and hereditary hemochromatosis resulting in end stage liver disease and the need for orthotopic liver transplantation is described. There has been no previously described case of the coexistence of these two diseases in a pediatric patient, resulting in end stage liver disease. The progression to cirrhosis in a patient of this age suggests a more rapid progression of the combined diseases than with either disease alone.
Miller
M
M
Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas, USA.
Crippin
J S
JS
Klintmalm
G
G
D000293:Adolescent; D002908:Chronic Disease; D018450:Disease Progression; D006432:Hemochromatosis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006526:Hepatitis C / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D008099:Liver / Q000473:pathology; D017093:Liver Failure / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D016031:Liver Transplantation; D008297:Male