title: [Study of the expression of proliferating cell nuclear antigen and p185 in non-small cell lung carcinoma].
abstract: We assessed immunohistochemical expression of p185 and the proliferating cell nuclear antigen (PCNA) in 68 patients undergoing surgery for non-small cell lung cancer. Adenocarcinoma of the lung was the histological type whose expression of p185 at levels exceeding 10% was greater to a statistically significant degree. Epidermoid carcinoma, on the other hand, was associated with the highest PCNA indices. Although these 2 markers had no prognostic value in the survival study, it must be pointed out that the longest survivors were patients with p185 expression less than 10% in neoplastic cells.
authors.affiliation: Servicio de Anatomía Patológica, Hospital General Universitario de Valencia.
authors.forename: P
authors.initials: P
authors.lastname: Alemany Monraval
authors.forename: M
authors.initials: M
authors.lastname: Martorell Cebollada
authors.forename: I
authors.initials: I
authors.lastname: Salvador Villalba
authors.forename: E
authors.initials: E
authors.lastname: Martínez Leandro
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000401:mortality; D002289:Carcinoma, Non-Small-Cell Lung / Q000737:chemistry* / Q000401:mortality; D002294:Carcinoma, Squamous Cell / Q000737:chemistry / Q000401:mortality; D003627:Data Interpretation, Statistical; D006801:Humans; D007124:Immunoenzyme Techniques; D008175:Lung Neoplasms / Q000737:chemistry* / Q000401:mortality; D011379:Prognosis; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000032:analysis*; D013997:Time Factors
chemical_list: D018809:Proliferating Cell Nuclear Antigen; D018719:Erb-b2 Receptor Tyrosine Kinases
vernacular_title: Estudio de la expresión del antígeno nuclear de proliferación celular y p185 en el carcinoma no microcítico de pulmón.