The H1-histamine antagonist Dithiaden inhibits human platelets in vitro.
Nosál
R
R
Department of Pharmacology, Medical Faculty, Masaryk University, Brno, Czech Republic.
Jancinová
V
V
Danihelová
E
E
D000244:Adenosine Diphosphate / Q000633:toxicity; D001582:Benzothiepins / Q000494:pharmacology*; D001792:Blood Platelets / Q000166:cytology / Q000187:drug effects*; D000001:Calcimycin / Q000633:toxicity; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D006801:Humans; D007476:Ionophores / Q000633:toxicity; D008315:Malondialdehyde / Q000097:blood; D009391:Nephelometry and Turbidimetry; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D013917:Thrombin / Q000633:toxicity; D013929:Thromboxane B2 / Q000097:blood
D001582:Benzothiepins; D006634:Histamine H1 Antagonists; D007476:Ionophores; D010975:Platelet Aggregation Inhibitors; D000001:Calcimycin; D008315:Malondialdehyde; D013929:Thromboxane B2; C100170:dithiadene; D000244:Adenosine Diphosphate; D013917:Thrombin