title: Geographic homogeneity and non-equilibrium patterns of mtDNA sequences in Tuscany, Italy.
abstract: The geographical distribution of 49 mtDNA sequences from 22 localities in Southern Tuscany, Italy, was studied by molecular analysis of variance, by a new spatial autocorrelation statistic specifically designed for sequence data and by reconstructing genealogies of haplotypes. All these methods indicated a high homogeneity of populations. Nevertheless, genetic variability showed significant departure from equilibrium expectations, in agreement with the predicted effects of a population expansion. We suggest that a past population expansion that was probably associated with a migrational wave and with local gene flow between localities prevented spatial structuring in Southern Tuscany.
authors.affiliation: Dipartimento di Biologia, Università di Padova, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Bertorelle
authors.forename: F
authors.initials: F
authors.lastname: Calafell
authors.forename: P
authors.initials: P
authors.lastname: Francalacci
authors.forename: J
authors.initials: J
authors.lastname: Bertranpetit
authors.forename: G
authors.initials: G
authors.lastname: Barbujani
mesh_terms: D000704:Analysis of Variance; D004272:DNA, Mitochondrial / Q000235:genetics*; D004641:Emigration and Immigration; D019143:Evolution, Molecular; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D007558:Italy
chemical_list: D004272:DNA, Mitochondrial