title: Computer-assisted interactive three-dimensional planning for neurosurgical procedures.
abstract: We have used three-dimensional reconstruction magnetic resonance imaging techniques to understand the anatomic complexity of operative brain lesions and to improve preoperative surgical planning. We report our experience with 14 cases, including intra- and extra-axial tumors and a vascular malformation. In each case, preoperative planning was performed using magnetic resonance imaging-based three-dimensional renderings of surgically critical structures, such as eloquent cortices, gray matter nuclei, white matter tracts, and blood vessels. Simulations, using the interactive manipulation of three-dimensional data, provided an efficient and comprehensive way to appreciate the anatomic relationships. Interactive three-dimensional computer-assisted preoperative simulations provided otherwise inaccessible information that was useful for the surgical removal of brain lesions.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: R
authors.initials: R
authors.lastname: Kikinis
authors.forename: P L
authors.initials: PL
authors.lastname: Gleason
authors.forename: T M
authors.initials: TM
authors.lastname: Moriarty
authors.forename: M R
authors.initials: MR
authors.lastname: Moore
authors.forename: E
authors.initials: E
authors.lastname: Alexander
authors.forename: P E
authors.initials: PE
authors.lastname: Stieg
authors.forename: M
authors.initials: M
authors.lastname: Matsumae
authors.forename: W E
authors.initials: WE
authors.lastname: Lorensen
authors.forename: H E
authors.initials: HE
authors.lastname: Cline
authors.forename: P M
authors.initials: PM
authors.lastname: Black
authors.forename: F A
authors.initials: FA
authors.lastname: Jolesz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009493:Neurosurgery / Q000295:instrumentation*; D013238:Stereotaxic Techniques / Q000295:instrumentation