[Genetic and environmental factors in essential arterial hypertension in an urban population of Cuba].
The present trial has been conducted in order to determine familia aggregation and the relationship between high blood pressure, inheritance and environmental factors. We studied 108 subjects (36 high blood pressure patients, 36 controls and 36 first degree relatives) ranging in age from 21 to 55 years. This case-control study was undertaken to determine risk factors. Multivariance analysis with logistic regression was carried out. Our results showed hereditary factors in 73.8% of the cases. Being the main gene autosomal recessive. Thus the main factor for high pressure is hereditary predisposition. Others factor are, body mass index and the coefficient waist-hip. We found no correlation with serum lipids.
Noa Ortega
F H
FH
Departamento en Salud Ambiental, Instituto Nacional de Enfermedades Respiratorias, México, D.F.
Castillo Herrera
J
J
Heredero Baute
L
L
Castro García
A
A
Bacallao Gallestey
J
J
Rojas Ramos
M
M
D000328:Adult; D000886:Anthropometry; D016022:Case-Control Studies; D016001:Confidence Intervals; D003462:Cuba; D004782:Environmental Health / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000209:etiology / Q000235:genetics*; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010375:Pedigree; D012307:Risk Factors; D014505:Urban Population / Q000706:statistics & numerical data
D008055:Lipids; D008074:Lipoproteins
Factores genéticos y ambientales en pacientes con hipertensión arterial esencial en una población urbana de Cuba.