title: Concurrent papillary and squamous carcinoma in a thyroglossal duct cyst: a case report.
abstract: Carcinomas of thyroglossal duct cysts are rare. Most are papillary carcinomas; only about 5% are squamous cell carcinomas. Only one case of mixed papillary and squamous cell carcinoma of a thyroglossal duct cyst has been reported so far. The authors present a second case, that of a 38-year-old man who was first seen with a midline neck lump. It was diagnosed clinically as a thyroglossal duct cyst and was locally excised. Pathological examination showed both a concurrent papillary carcinoma and a squamous cell carcinoma. Treatment consisted of a near-total thyroidectomy, ablative radioactive iodine and adjuvant external radiation therapy. The authors review the literature and explain the rationale behind their choice of treatment.
authors.affiliation: Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Ont.
authors.forename: W B
authors.initials: WB
authors.lastname: Kwan
authors.forename: F F
authors.initials: FF
authors.lastname: Liu
authors.forename: D
authors.initials: D
authors.lastname: Banerjee
authors.forename: L E
authors.initials: LE
authors.lastname: Rotstein
authors.forename: R W
authors.initials: RW
authors.lastname: Tsang
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D013955:Thyroglossal Cyst / Q000150:complications*; D013964:Thyroid Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy
chemical_list: D007457:Iodine Radioisotopes