[Primary cutaneous nocardia asteroides nocardiosis in an immunocompromised patient].
BACKGROUND
Nocardiasis is caused by a germ belonging to the Actinomycetales order. Skin disease usually occurs as a secondary localization of a pulmonary infection in an immunocompromised patient. Purely cutaneous lesions usually occur in immunocompetent subjects.


METHODS
We observed primary cutaneous nocardiasis due to N. asteroides with a cold abscess in a patient with a pemphigoid given immunodepression treatment.


CONCLUSIONS
Primary cutaneous nocardiasis can occur by direct contamination of a skin wound. In our patient with a pemphigoid given immunodepression treatment, the erosion of a pemphigoid bulla and general corticosteroid treatment favoured the localized infection. Cure could not be obtained until after 7 months treatment. This long course can be explained by the need to continue high-dose general corticosteroids to control the pemphigoid.
Marck
Y
Y
Service de Dermatologie, Hôpital Saint-Charles, Montpellier.
Meunier
L
L
Perez
C
C
Meynadier
J
J
D000368:Aged; D006801:Humans; D016867:Immunocompromised Host; D007868:Leg Dermatoses / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D009617:Nocardia Infections / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D009616:Nocardia asteroides; D010391:Pemphigoid, Bullous / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D017192:Skin Diseases, Bacterial / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D011241:Prednisone
Nocardiose cutanée primitive a nocardia asteroides chez un malade immunodéprimé.