title: Systemic, metastatic, eu- and heterotope tumours of the heart in necropsied dogs.
abstract: 10,090 dissections of dogs exhibited 2631 neoplastic processes of which 309 involved the heart in the form of eu- and heteropic tumours. The most common primary and/or secondary heart tumour type was hemangiosarcoma (n = 187), followed by paraganglioma (n = 46), carcinoma (n = 33), malignant lymphoma (n = 12), thyroid heart base tumour (n = 9), melanoma (n = 7), mast cell tumour (n = 3) and blastoma (n = 2). The tumour diagnoses were immunohistochemically proved by various antibodies to cytokeratins, vimentin, GFAP, NSE, von Willebrand factor, CD3, CD45RA, S100, thyroglobulin as well as histochemically with argyrophilic, Fontana-Masson and heterochromatic reactions. The odds ratio (OR) for breed and tumour prevalences were determined: German shepherds showed the highest OR for hemangiosarcomas and boxers for paragangliomas.
authors.affiliation: Institut für Veterinär-Pathologie, Freien Universität Berlin, Germany.
authors.forename: J H
authors.initials: JH
authors.lastname: Walter
authors.forename: R
authors.initials: R
authors.lastname: Rudolph
mesh_terms: D000818:Animals; D001947:Breeding; D002277:Carcinoma / Q000453:epidemiology / Q000662:veterinary; D004283:Dog Diseases / Q000145:classification / Q000453:epidemiology*; D004285:Dogs; D005260:Female; D006338:Heart Neoplasms / Q000145:classification / Q000453:epidemiology / Q000662:veterinary*; D006394:Hemangiosarcoma / Q000453:epidemiology / Q000662:veterinary; D008223:Lymphoma / Q000453:epidemiology / Q000662:veterinary; D008297:Male; D012515:Mast-Cell Sarcoma / Q000453:epidemiology / Q000662:veterinary; D008545:Melanoma / Q000453:epidemiology / Q000662:veterinary; D010235:Paraganglioma / Q000453:epidemiology / Q000662:veterinary; D015995:Prevalence