Protracted post-traumatic confusional state treated with physostigmine.
A case study is presented of confusion in a head-injured man, lasting for more than 2 years, when intermittent treatment with physostigmine resulted in progressive improvement in both confusion and usable cognitive functions. Aetiological mechanisms and implications for treatment plans are discussed.
Eames
P
P
Grafton Manor Brain Injury Rehabilitation Unit, Northants, UK.
Sutton
A
A
D001364:Awareness / Q000187:drug effects; D002800:Cholinesterase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D003221:Confusion / Q000188:drug therapy* / Q000523:psychology; D004569:Electroencephalography / Q000187:drug effects; D005500:Follow-Up Studies; D015600:Glasgow Coma Scale; D016489:Head Injuries, Closed / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010830:Physostigmine / Q000009:adverse effects / Q000627:therapeutic use*
D002800:Cholinesterase Inhibitors; D010830:Physostigmine