Bed rest decreases whole-body protein turnover in post-absorptive man.
1. Whole-body protein turnover was measured using the [15N]glycine tracer technique in 10 post-absorptive healthy volunteers during normal daily activities and a period of bed rest. 2. Bed rest reduced whole-body protein turnover (25%), synthesis (26%) and breakdown (25%), but short-term urinary nitrogen excretion remained unchanged.
Bettany
G E
GE
Department of Human Nutrition, London Hospital Medical College, U.K.
Ang
B C
BC
Georgiannos
S N
SN
Halliday
D
D
Powell-Tuck
J
J
D000042:Absorption; D000328:Adult; D000641:Ammonia / Q000032:analysis; D001510:Bed Rest; D005260:Female; D006801:Humans; D008297:Male; D009590:Nitrogen Radioisotopes / Q000493:pharmacokinetics; D011506:Proteins / Q000378:metabolism*; D011849:Radioactive Tracers; D014508:Urea / Q000032:analysis
D009590:Nitrogen Radioisotopes; D011506:Proteins; D011849:Radioactive Tracers; D000641:Ammonia; D014508:Urea