[PUVA therapy for cutaneous acute graft-versus-host disease--a case report].
We performed 8-methoxypsolaren and ultraviolet A (PUVA) therapy as a second line treatment for stage +3 cutaneous acute graft-versus-host disease (GVHD) in a 10-year-old girl who had undergone unrelated bone marrow transplantation. Although prednisolone as first line therapy was not effective, the cutaneous lesion began to improve after several times of PUVA treatment and completely disappeared following 11 times of irradiation without additive systemic immunosuppressive therapy. PUVA therapy was considered as a useful treatment for cutaneous acute GVHD.
Inamitsu
T
T
Division of Pediatrics, Kyushu University, Fukuoka, Japan.
Inoue
M
M
Akiyoshi
H
H
Honda
K
K
Shibuya
T
T
Nakayama
H
H
Ueda
K
K
D000208:Acute Disease; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D002648:Child; D005260:Female; D006086:Graft vs Host Disease / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D011701:PUVA Therapy; D012871:Skin Diseases / Q000188:drug therapy*