title: A family of halobacterial transducer proteins.
abstract: A DNA probe to the signaling domain of a halobacterial transducer for phototaxis (HtrI) was used to clone and sequence four members of a new family of transducer proteins (Htps) in Halobacterium salinarium potentially involved in chemo- or phototactic signal transduction. The signaling domains in these proteins have 31-43% identity when compared with each other or with their bacterial analogs, the methyl-accepting chemotaxis proteins. An additional region of homology found in three of the Htps has 31-43% identity with HtrI. The Htps contain from 0 to 3 transmembrane helices and Western blotting showed that HtpIII is soluble. The arrangement of the domains in these Htps suggests a modular architecture in their construction.
authors.affiliation: Max-Planck-Institut for Biochemistry, Martinsried, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Rudolph
authors.forename: B
authors.initials: B
authors.lastname: Nordmann
authors.forename: K F
authors.initials: KF
authors.lastname: Storch
authors.forename: H
authors.initials: H
authors.lastname: Gruenberg
authors.forename: K
authors.initials: K
authors.lastname: Rodewald
authors.forename: D
authors.initials: D
authors.lastname: Oesterhelt
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D001483:Base Sequence; D015153:Blotting, Western; D015342:DNA Probes; D006216:Halobacteriaceae / Q000737:chemistry / Q000235:genetics*; D008745:Methylation; D008969:Molecular Sequence Data; D011485:Protein Binding / Q000235:genetics; D011487:Protein Conformation; D015398:Signal Transduction / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D015342:DNA Probes