Myocardial necrosis and QRS complex changes in the ischemia-reperfusion setting in a baboon model.
BACKGROUND
This study was performed in attempt to draw a correlation between the percentage of myocardial infarction across the left ventricular wall and changes in the QRS complex in the epicardial ECG in a primate model of ischemia-reperfusion injury.


METHODS
Myocardial infarction was induced in six baboons by ligating the left anterior descending coronary artery for 2h. Using ECG leads, the presence of Q and R waves was recorded along with their associated left ventricular wall thickness.


CONCLUSIONS
The results indicate that Q-wave development and R-wave loss can be correlated with depth of infarct.
Premaratne
S
S
Department of Surgery, John A. Burns School of Medicine, Queen's Medical Center, Honolulu, Hawaii, USA.
LaPenna
W F
WF
Siu
B
B
McNamara
J J
JJ
D000818:Animals; D004195:Disease Models, Animal; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000473:pathology; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000175:diagnosis* / Q000473:pathology; D009206:Myocardium / Q000473:pathology*; D009336:Necrosis; D010215:Papio