title: [Primary cutaneous nocardia asteroides nocardiosis in an immunocompromised patient].
abstract: BACKGROUND
  Nocardiasis is caused by a germ belonging to the Actinomycetales order. Skin disease usually occurs as a secondary localization of a pulmonary infection in an immunocompromised patient. Purely cutaneous lesions usually occur in immunocompetent subjects.
  
  
  METHODS
  We observed primary cutaneous nocardiasis due to N. asteroides with a cold abscess in a patient with a pemphigoid given immunodepression treatment.
  
  
  CONCLUSIONS
  Primary cutaneous nocardiasis can occur by direct contamination of a skin wound. In our patient with a pemphigoid given immunodepression treatment, the erosion of a pemphigoid bulla and general corticosteroid treatment favoured the localized infection. Cure could not be obtained until after 7 months treatment. This long course can be explained by the need to continue high-dose general corticosteroids to control the pemphigoid.
authors.affiliation: Service de Dermatologie, Hôpital Saint-Charles, Montpellier.
authors.forename: Y
authors.initials: Y
authors.lastname: Marck
authors.forename: L
authors.initials: L
authors.lastname: Meunier
authors.forename: C
authors.initials: C
authors.lastname: Perez
authors.forename: J
authors.initials: J
authors.lastname: Meynadier
mesh_terms: D000368:Aged; D006801:Humans; D016867:Immunocompromised Host; D007868:Leg Dermatoses / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D009617:Nocardia Infections / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D009616:Nocardia asteroides; D010391:Pemphigoid, Bullous / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D017192:Skin Diseases, Bacterial / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D011241:Prednisone
vernacular_title: Nocardiose cutanée primitive a nocardia asteroides chez un malade immunodéprimé.