title: Treatment of hepatocellular carcinoma smaller than 5 cm by transcatheter arterial chemoembolization.
abstract: To assess the effectiveness of transcatheter arterial chemoembolization (TACE) in the treatment of small hepatocellular carcinoma (HCC) and to analyze the prognostic factors, a total of 77 patients with histologically proven HCC, < or = 5 cm in diameter, were enrolled for the study and followed for more than 2 years, The overall cumulative 1-, 2-, and 3-year survival rates were 79.2%, 50.6% and 36.7%, respectively. The median survival time of Child-Pugh's A patients was 990 +/- 146 days, which was significantly better than the median survival time of Child-Pugh's B patients (450 +/- 82 days) Furthermore, positive HBeAg and alpha-Fetoprotein (AFP) were factors close to statistically significant. In contrast, sex, age, HBsAg, Anti-HCV, tumor type, tumor size and tumor number were not related to the prognosis in small HCC who received TACE.
authors.affiliation: Department of Internal Medicine, Kaohsiung Medical College Hospital, Taiwan, Republic of China.
authors.forename: M Y
authors.initials: MY
authors.lastname: Hsieh
authors.forename: S C
authors.initials: SC
authors.lastname: Chen
authors.forename: S N
authors.initials: SN
authors.lastname: Lu
authors.forename: L Y
authors.initials: LY
authors.lastname: Wang
authors.forename: J F
authors.initials: JF
authors.lastname: Tsai
authors.forename: W L
authors.initials: WL
authors.lastname: Chuang
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Lin
authors.forename: W Y
authors.initials: WY
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D012044:Regression Analysis