[Prevention of polymorphous ventricular tachycardia in patients with congenital long QT interval syndrome].
Patients with the Romano-Ward long QT interval syndrome run a high risk of sudden cardiac death. Beta-blockers of the sympathetic nerve are effective treatment. Some patients die suddenly despite this treatment. The treatment of choice is a combination of beta-blockers of the sympathetic nerve and cardiostimulation. The authors describe a group of their own five patients from three families with the Romano-Ward syndrome. The course was favourable. The stimulation rate needed for normalization of the QT interval and a favourable clinical development was 78 +/- 6 imp./min. Based on data in the literature and their own experience the authors recommended combined treatment with beta-blockers and cardiostimulation in patients with the Romano-Ward syndrome, if monotherapy with beta-blockers is not effective.
Kaliská
G
G
Interná klinika A Nemocnice F.D. Roosevelta, Banská Bystrica.
Kmec
P
P
Nedĕlová
I
I
Szentivanyi
M
M
Skamla
J
J
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000517:prevention & control*
D000319:Adrenergic beta-Antagonists
Moznosti prevencie polymorfnej komorovej tachykardie u pacientov s kongenitálnym syndrómom dlhého QT intervalu.