title: Idiopathic ventricular fibrillation initiated by a short-coupled ventricular premature beat.
abstract: We report the case of a 38-year-old man who had idiopathic ventricular fibrillation (VF) which initiated by abnormally short-coupled ventricular premature beats. VF was successfully prevented by the combination of pilsicainide, propranolol, and verapamil. In particular, the effects of pilsicainide are assumed to exert an important effect in controlling this arrhythmia. Class Ic drugs may be effective for preventing VF initiated by short-coupled VPBs.
authors.affiliation: Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Nakazato
authors.forename: Y
authors.initials: Y
authors.lastname: Nakata
authors.forename: M
authors.initials: M
authors.lastname: Yasuda
authors.forename: S
authors.initials: S
authors.lastname: Yamagami
authors.forename: T
authors.initials: T
authors.lastname: Tokano
authors.forename: K
authors.initials: K
authors.lastname: Nakazato
authors.forename: M
authors.initials: M
authors.lastname: Sumiyoshi
authors.forename: S
authors.initials: S
authors.lastname: Ogura
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D005117:Cardiac Complexes, Premature / Q000150:complications* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D006801:Humans; D008012:Lidocaine / Q000031:analogs & derivatives / Q000627:therapeutic use; D008297:Male; D011433:Propranolol / Q000627:therapeutic use; D014693:Ventricular Fibrillation / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D014700:Verapamil / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; D008012:Lidocaine; D011433:Propranolol; C042288:pilsicainide; D014700:Verapamil