title: Imaging of olfactory neuroblastoma by In-111 bleomycin complex.
abstract: No other successful nuclear method, besides bone scanning, has been reported in the literature for in vivo imaging of olfactory neuroblastoma. In this article, excellent uptake is reported by an In-111 labeled bleomycin complex (BLMC) in the ethmoid region of a histologically confirmed olfactory neuroblastoma. The uptake of BLMC was 0.7 x 10(-3)% ID/g at 48 hours after injection, and tumor-to-muscle and tumor-to-fat ratios were 6:1 and 11:1, respectively. The authors conclude that BLMC should be considered as a useful imaging agent, and the BLMC has potential as a radiochemotherapeutic agent against an olfactory neuroblastoma.
authors.affiliation: Department of Oncology, Helsinki University Central Hospital, Finland.
authors.forename: A P
authors.initials: AP
authors.lastname: Jekunen
authors.forename: K J
authors.initials: KJ
authors.lastname: Kairemo
authors.forename: H A
authors.initials: HA
authors.lastname: Ramsay
authors.forename: M J
authors.initials: MJ
authors.lastname: Kajanti
mesh_terms: D000368:Aged; D001761:Bleomycin / Q000031:analogs & derivatives*; D018304:Esthesioneuroblastoma, Olfactory / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D009296:Nasal Cavity / Q000000981:diagnostic imaging*; D009669:Nose Neoplasms / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D011877:Radionuclide Imaging; D013997:Time Factors
chemical_list: D007205:Indium Radioisotopes; D009942:Organometallic Compounds; C047120:indium-bleomycin; D001761:Bleomycin