[Usefulness and limitation of serum tumor markers in diagnosis of lung cancer].
In the clinical practice of lung cancer, serum tumor markers are important laboratory tests and their use is wide spread. Among the various markers for lung cancer, the usefulness of CEA, SLX, SCC and NSE has been firmly established. These markers cannot be used routinely to screen for lung cancer but may be used as complementary tools for diagnosing the tumor. Elevated levels of these markers also appear to be useful for monitoring the response to therapy and tumor progression. CYFRA21-1 and ProGRP, new tumor markers with relatively high sensitivity and specificity to lung cancer, were recently developed. These tumor markers may be useful tools for early detection of lung cancer.
Fukuda
M
M
Department of Respiratory Medicine, Japanese Red Cross Nagasaki Atomic Bomb Hospital.
Oka
M
M
D000951:Antigens, Neoplasm / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003937:Diagnosis, Differential; D005768:Gastrointestinal Hormones / Q000032:analysis; D006801:Humans; D007381:Intermediate Filament Proteins / Q000032:analysis; D053539:Keratin-19; D007633:Keratins; D016256:Lewis X Antigen / Q000032:analysis; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009367:Neoplasm Staging; D010446:Peptide Fragments / Q000032:analysis; D010455:Peptides / Q000032:analysis; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D011994:Recombinant Proteins / Q000032:analysis
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D005768:Gastrointestinal Hormones; D007381:Intermediate Filament Proteins; D053539:Keratin-19; D016256:Lewis X Antigen; D010446:Peptide Fragments; D010455:Peptides; D011994:Recombinant Proteins; C102012:antigen CYFRA21.1; C087079:pro-gastrin-releasing peptide (31-98); D007633:Keratins; D010751:Phosphopyruvate Hydratase