title: Molecular thanatopsis: a discourse on the BCL2 family and cell death.
authors.affiliation: Howard Hughes Medical Institute, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.
authors.forename: E
authors.initials: E
authors.lastname: Yang
authors.forename: S J
authors.initials: SJ
authors.lastname: Korsmeyer
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D030801:Animals, Genetically Modified; D017209:Apoptosis / Q000235:genetics; D051017:Apoptosis Regulatory Proteins; D017173:Caenorhabditis elegans / Q000235:genetics; D029742:Caenorhabditis elegans Proteins; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology; D020170:Caspase 1; D016923:Cell Death / Q000235:genetics*; D002455:Cell Division; D002883:Chromosomes, Human, Pair 14 / Q000235:genetics; D002887:Chromosomes, Human, Pair 18 / Q000235:genetics; D003546:Cysteine Endopeptidases / Q000737:chemistry; D015972:Gene Expression Regulation, Neoplastic; D015967:Gene Expression Regulation, Viral / Q000187:drug effects; D005803:Genes, Immunoglobulin; D015801:Helminth Proteins / Q000235:genetics / Q000502:physiology; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D008224:Lymphoma, Follicular / Q000188:drug therapy / Q000235:genetics / Q000401:mortality; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000235:genetics / Q000401:mortality; D051379:Mice; D018345:Mice, Knockout; D008969:Molecular Sequence Data; D005810:Multigene Family; D009857:Oncogenes; D011379:Prognosis; D011401:Promoter Regions, Genetic; D055503:Protein Multimerization; D011518:Proto-Oncogene Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D019253:Proto-Oncogene Proteins c-bcl-2; D016271:Proto-Oncogene Proteins c-myc / Q000502:physiology; D051381:Rats; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D014178:Translocation, Genetic / Q000235:genetics; D051028:bcl-2-Associated X Protein; D051025:bcl-Associated Death Protein; D051020:bcl-X Protein
chemical_list: D051017:Apoptosis Regulatory Proteins; C494819:BAD protein, human; C494811:BCL2L1 protein, human; C494820:Bad protein, mouse; C494821:Bad protein, rat; C494828:Bax protein, rat; C494812:Bcl2l1 protein, mouse; C494813:Bcl2l1 protein, rat; D029742:Caenorhabditis elegans Proteins; D002352:Carrier Proteins; C087233:Ced-9 protein, C elegans; D015801:Helminth Proteins; D007143:Immunoglobulin Heavy Chains; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D016271:Proto-Oncogene Proteins c-myc; D051028:bcl-2-Associated X Protein; D051025:bcl-Associated Death Protein; D051020:bcl-X Protein; D003546:Cysteine Endopeptidases; D020170:Caspase 1