title: Efficacy of traditional rice-lentil-yogurt diet, lactose free milk protein-based formula and soy protein formula in management of secondary lactose intolerance with acute childhood diarrhoea.
abstract: Secondary lactose intolerance is often a cause of prolongation of diarrhoeal episodes. As appropriate management of lactose intolerance is elimination of lactose from diet, expansive lactose free formulae are often prescribed in acute childhood diarrhoea without establishing diagnosis of lactose intolerance. Since cheap weaning diets made from locally available cereals have been found effective in management of persistent diarrhoea, we postulated that same weaning diet made of rice lentil and yogurt (K-Y diet) could be effectively used in management of acute childhood diarrhoea associated with secondary lactose intolerance. We compared this K-Y diet with milk protein-based lactose free and soy-protein formula. Thirty children between 3-18 months of age completed dietary trial for 72 h. Of these nine children received K-Y diet (Group A), four children received milk protein-based formula (Group B) and 11 children received soy protein formula (Group C). Stool frequency was significantly reduced in children in Group A (13 +/- 6 on day 1 to 6 +/- 5 on day 3) and in Group B (13 +/- 5 on day 1 to 7 +/- 4 on day 3), but not in Group C (13 +/- 4 on day 1 to 10 +/- 8 on day 3). No significant difference was observed in intake of diet, total calories intake, and fluid intake among the three groups. It is concluded that cheap weaning diet made of locally available cereals and yogurt can be used effectively in management of secondary lactose intolerance associated with acute childhood diarrhoea.
authors.affiliation: Department of Paediatrics, Aga Khan University, Karachi, Pakistan.
authors.forename: S Q
authors.initials: SQ
authors.lastname: Nizami
authors.forename: Z A
authors.initials: ZA
authors.lastname: Bhutta
authors.forename: A M
authors.initials: AM
authors.lastname: Molla
mesh_terms: D002648:Child; D002675:Child, Preschool; D003968:Diarrhea, Infantile / Q000178:diet therapy* / Q000209:etiology; D004044:Dietary Proteins / Q000008:administration & dosage; D007887:Fabaceae; D005260:Female; D005526:Food, Formulated; D006801:Humans; D007223:Infant; D007225:Infant Food; D007787:Lactose Intolerance / Q000150:complications / Q000178:diet therapy*; D008297:Male; D012275:Oryza; D010946:Plants, Medicinal; D011379:Prognosis; D011446:Prospective Studies; D013025:Glycine max; D015014:Yogurt
chemical_list: D004044:Dietary Proteins