title: [Complications of immunotherapy with BCG. Report of a case with retractile bladder].
abstract: OBJECTIVE
  We report a case of contracted bladder following BCG immunotherapy to prevent recurrence of a superficial bladder carcinoma. Other possible complications and their prevention are also discussed.
  
  
  METHODS
  The patient had extreme contracted bladder and marked bilateral ureterohydronephrosis that required cystectomy and bladder substitution. The histopathological examination revealed detrusor muscle fibrosis without inflammation.
  
  
  RESULTS
  Surgery achieved good results and the patient is disease-free 5 months postoperatively.
  
  
  CONCLUSIONS
  The major complication that must be avoided is absorption following traumatic catheterization. Recognizing the early symptoms, particularly cystitis, together with adequate and early treatment of the localized effects can significantly reduce the incidence of severe toxicity.
authors.affiliation: Servicio de urología, Hospital Universitario Virgen del Rocío, Sevilla, España.
authors.forename: F J
authors.initials: FJ
authors.lastname: Torrubia Romero
authors.forename: J
authors.initials: J
authors.lastname: Martínez Rodríguez
authors.forename: N
authors.initials: N
authors.lastname: Cruz Navarro
authors.forename: A
authors.initials: A
authors.lastname: Ramírez Mendoza
authors.forename: A
authors.initials: A
authors.lastname: Soltero González
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects*; D001500:BCG Vaccine / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D001745:Urinary Bladder Diseases / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000628:therapy
chemical_list: D000276:Adjuvants, Immunologic; D001500:BCG Vaccine
vernacular_title: Complicaciones de la immunoterapia con BCG. A propósito de un caso de vejiga retráctil.