title: Glutathione inhibition of silver-enhanced sodium transport across toad skin.
abstract: Silver stimulated short-circuit current and transepithelial potential difference. Glutathione inhibited the silver-induced short-circuit current. There was a dose-response inhibition of silver-induced short-circuit current by glutathione. The silver-induced short-circuit current is carried by a net active sodium transfer from the outside to the inside bathing solution.
authors.affiliation: Department of Physiology, College of Medicine, University of Florida, Gainesville 32610, USA.
authors.forename: G A
authors.initials: GA
authors.lastname: Gerencser
authors.forename: S Y
authors.initials: SY
authors.lastname: Loo
mesh_terms: D000818:Animals; D002024:Bufo marinus; D003545:Cysteine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004566:Electrodes; D005260:Female; D005978:Glutathione / Q000494:pharmacology*; D066298:In Vitro Techniques; D017136:Ion Transport / Q000187:drug effects; D008297:Male; D012834:Silver / Q000037:antagonists & inhibitors*; D012867:Skin / Q000187:drug effects* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism*; D014667:Vasopressins / Q000494:pharmacology
chemical_list: D014667:Vasopressins; D012834:Silver; D012964:Sodium; D005978:Glutathione; D003545:Cysteine