title: The management of retroperitoneal soft tissue sarcomas.
abstract: Over a 5-year period, all retroperitoneal soft tissue sarcomas (119) referred to the Royal Marsden Hospital, London, U.K., were recorded prospectively on a database and managed with a consistent treatment policy. On multivariate analysis, the significant factors responsible for determining prognosis were grade and completeness of excision. Despite improvements in surgical clearance rates (nearly 50% completely excised in this series), the prognosis was poor with 2- and 5-year survival rates of 53 and 20%, respectively. Further improvements in survival rates will depend on better adjuvant treatment.
authors.affiliation: Soft Tissue Sarcoma Unit, Royal Marsden Hospital, London, U.K.
authors.forename: M P
authors.initials: MP
authors.lastname: Jenkins
authors.forename: J C
authors.initials: JC
authors.lastname: Alvaranga
authors.forename: J M
authors.initials: JM
authors.lastname: Thomas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications; D011446:Prospective Studies; D012186:Retroperitoneal Neoplasms / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D012509:Sarcoma / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D016019:Survival Analysis