title: alpha-Tocopherol concentrations in milk and plasma during clinical Escherichia coli mastitis.
abstract: Eighteen cows were challenged by intramammary infusion with Escherichia coli 727 to determine the effects of acute clinical mastitis on alpha-tocopherol concentrations in plasma and milk. Cows were fed diets supplemented with 1000 IU of vitamin E/d from calving through the experimental period. At challenge, geometric mean DIM was 33 d. Each mammary quarter was diagnosed with an IMI and clinical mastitis at 24 and 48 h after challenge. The alpha-tocopherol concentrations in milk from challenged quarters were approximately 60% greater by 24 and 48 h after challenge than concentrations at prechallenge and 168 h postchallenge. Plasma alpha-tocopherol concentrations did not change after intramammary challenge. The alpha-tocopherol in plasma and milk was correlated at 48 and 168 h postchallenge but not at prechallenge or 24 h postchallenge. Milk alpha-tocopherol and SCC were correlated positively across all sample periods. Milk fat and milk alpha-tocopherol concentrations were correlated at each sample period except 24 h postchallenge. Increases in milk alpha-tocopherol during clinical mastitis were not correlated to milk production, DMI, or BSA concentration in milk. Changes in milk alpha-tocopherol concentration during clinical mastitis were similar to the dynamics of milk SCC.
authors.affiliation: Department of Dairy Science, Ohio State University, Wooster 44691, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Hogan
authors.forename: W P
authors.initials: WP
authors.lastname: Weiss
authors.forename: K L
authors.initials: KL
authors.lastname: Smith
authors.forename: L M
authors.initials: LM
authors.lastname: Sordillo
authors.forename: S N
authors.initials: SN
authors.lastname: Williams
mesh_terms: D000818:Animals; D002417:Cattle; D002452:Cell Count; D004927:Escherichia coli Infections / Q000097:blood / Q000378:metabolism / Q000662:veterinary*; D005260:Female; D008414:Mastitis, Bovine / Q000097:blood / Q000378:metabolism* / Q000382:microbiology; D008892:Milk / Q000166:cytology / Q000378:metabolism*; D012710:Serum Albumin, Bovine / Q000378:metabolism; D014810:Vitamin E / Q000097:blood / Q000378:metabolism*
chemical_list: D014810:Vitamin E; D012710:Serum Albumin, Bovine