[The immune reactivity of patients with chronic bronchitis on vaccinal therapy].
The treatment of 17 patients having chronic obstructive bronchitis with a combined vaccine resulted in a rise in the number of T lymphocytes and T suppressors, as well as a simultaneous increase in their functional activity, in these patients. Moreover, an increase in the ingestive activity of neutrophils and in the concentration of immune complexes was registered. Treatment with the vaccine containing Staphylococcus aureus, Klebsiella pneumoniae, Proteus and Escherichia coli antigens facilitated an increase in the titers of antibodies to most antigens contained in the vaccine and in the resistance of the body to infection. Vaccinal therapy made it possible to achieve a significant prolongation of the period of remission.
Sukhovskaia
O A
OA
Aleksandrova
N I
NI
Egorova
N B
NB
Efremova
V N
VN
D000328:Adult; D000917:Antibody Formation; D000937:Antigen-Antibody Reactions; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D001991:Bronchitis / Q000276:immunology* / Q000628:therapy*; D002908:Chronic Disease; D004341:Drug Evaluation; D004926:Escherichia coli / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D016233:Immunotherapy, Active; D007711:Klebsiella pneumoniae / Q000276:immunology*; D008875:Middle Aged; D011511:Proteus / Q000276:immunology*; D012074:Remission Induction; D013211:Staphylococcus aureus / Q000276:immunology*; D013997:Time Factors; D017778:Vaccines, Combined / Q000627:therapeutic use
D001428:Bacterial Vaccines; D017778:Vaccines, Combined
Immunoreaktivnost' bol'nykh khronicheskim bronkhitom pri vaktsinoterapii.