title: [Noninvasive intermittent ventilation. A prospective data collection in patients with hypoventilation syndrome].
abstract: BACKGROUND
  Noninvasive intermittent ventilation is usually performed in patients with severe ventilatory pump disorder. From 1988 to 3/1995 we treated 163 patients with the aim of home mechanical ventilation (HMV).
  
  
  RESULTS
  In March 1993 115 of these 163 patients practiced HMV, 22 had already died and 26 had rejected or broken off ventilation therapy. The 115 patients were classified in three main diagnostic groups: Scoliosis or chest wall disease (n = 76), COPD (n = 11) and neuromuscular disease (n = 28). The mean pCO2 at rest of all patients before ventilation therapy was 56 (+/- 12) Torr and fell to 46 (+/- 5) Torr in the course of therapy. The maximum statical inspiration pressure PImax rose from average 3, 8 (+/- 2, 3) to 4, 9 (+/- 2, 0) kPa. There was a probability of surviving two years after onset of ventilation therapy of 85% in the scoliosis group, of 60% in the neuromuscular group and of 30% in the COPD group.
  
  
  CONCLUSIONS
  According to results of others home ventilation therapy was very successful in patients with chest wall disease. In some patients with neuromuscular disorder quality of life could be improved and life prolonged. Only half of the COPD patients could be treated successfully, whereas the other half had no benefit from noninvasive ventilation therapy.
authors.affiliation: Pneumologische Klinik im Zentralkrankenhaus Gauting.
authors.forename: F
authors.initials: F
authors.lastname: Bullemer
authors.forename: S
authors.initials: S
authors.lastname: Heindl
authors.forename: J
authors.initials: J
authors.lastname: Pahnke
authors.forename: O
authors.initials: O
authors.lastname: Karg
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006699:Home Care Services; D006801:Humans; D007384:Intermittent Positive-Pressure Breathing; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012131:Respiratory Insufficiency / Q000209:etiology / Q000401:mortality / Q000534:rehabilitation*; D012648:Self Care; D015996:Survival Rate
vernacular_title: Nichtinvasive intermittierende Beatmung. Eine prospektive Datenerhebung bei Patienten mit Hypoventilationssyndrom.