title: [Preoperative evaluation of hepatic functional reserve for patients with primary liver carcinoma].
abstract: The retention rate of indocyanine green at 15 minutes (ICGR15) and routine hepatic function tests were performed preoperatively in 122 cases of patients with primary liver carcinomas in order to evaluate the hepatic functional reserve. These patients were divided into 3 groups according to the post-operative changes of hepatic function. 87, 24 and 11 cases showed good recovery (group good), mild liver dysfunction (group mild) and severe liver dysfunction (group severe) respectively, after operation. The differences of Pugh's points, ALT, ALP and gamma-GT between each two groups were not significant. But, the differences of ICGR15 were very significant. We also divided all cases into 3 groups according to the value of ICGR15. The incidence of liver dysfunction was 6.0% in group A (ICGR15 < 10.0%), 27.8% in group B (ICGBR15 = 10.0%-20.0%) and 76.5% in group C (ICGR15 > 20.0%), respectively. The difference of the incidences of liver dysfunction in these 3 groups was very significant. The higher the ICGR15, the more the incidence of liver dysfunction. These results demonstrated that ICGR15 is a good indicator to judge hepatic functional reserve for patients with primary liver carcinoma.
authors.affiliation: Tumor Hospital, Sun yat-sen University of Medical Sciences, Guangzhou.
authors.forename: Y
authors.initials: Y
authors.lastname: Yuan
authors.forename: G
authors.initials: G
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000503:physiopathology* / Q000601:surgery; D004396:Coloring Agents; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007208:Indocyanine Green; D008099:Liver / Q000503:physiopathology*; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011446:Prospective Studies
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green