title: Ascosteroside, a new antifungal agent from Ascotricha amphitricha. II. Isolation and structure elucidation.
abstract: The novel antifungal agent ascosteroside (1) was isolated from cultured broth of Ascotricha amphitricha (ATCC 74237). The structure based on spectroscopic data was determined to be an alpha-linked glycoside of a lanostane-type triterpenoid.
authors.affiliation: Bristol-Myers Squibb Company, Pharmaceutical Research Institute, Wallingford, Connecticut 06492, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Leet
authors.forename: S
authors.initials: S
authors.lastname: Huang
authors.forename: S E
authors.initials: SE
authors.lastname: Klohr
authors.forename: K D
authors.initials: KD
authors.lastname: McBrien
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D013098:Xylariales
chemical_list: D000935:Antifungal Agents; D006027:Glycosides; D014315:Triterpenes; C100703:ascosteroside