title: Laryngeal lymphoma derived from mucosa-associated lymphoid tissue.
abstract: Extranodal lymphomas account for as many as 40% of non-Hodgkin's lymphomas, and most arise in the gastrointestinal tract, but other mucosal organs may be involved, especially the upper aerodigestive tract. Low-grade B-cell lymphomas arising in the gastrointestinal tract and other mucosae have been found to recapitulate the structure and cytologic features of mucosa-associated lymphoid tissue (MALT). Histologically low-grade MALT lymphomas are characterized by centrocyte-like B-cells with a phenotype similar to that of so-called marginal zone B-cells. Tumors evolving from MALT are generally rare among lymphomas of the upper aerodigestive tract, but a few cases of laryngeal lymphomas derived from MALT have been reported. Primary MALT lymphoma of the larynx should always be considered in tumors with histopathologic features of low-grade B-cell lymphoma, or so-called pseudolymphoma.
authors.affiliation: Institut für Pathologie, Universität Tubingen, Germany.
authors.forename: H P
authors.initials: HP
authors.lastname: Horny
authors.forename: A
authors.initials: A
authors.lastname: Ferlito
authors.forename: A
authors.initials: A
authors.lastname: Carbone
mesh_terms: D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D007830:Larynx / Q000473:pathology* / Q000648:ultrastructure; D018442:Lymphoma, B-Cell, Marginal Zone / Q000473:pathology* / Q000648:ultrastructure; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000648:ultrastructure; D012189:Retrospective Studies