Expression of V-SRC and chromosome analysis of a newly established cell line from rat sarcoma induced by an avian retroviral strain.
In the newly established rat sarcoma cell line LSR-SF (SR) expression of pp60v-src was detected. Karyotype analyses revealed various chromosome aberrations during prolonged passaging of the tumor cells in vitro. Polyploidy was found to be a characteristic feature of the line studied. A large metacentric chromosome persistently present in the cells was accepted as a line marker.
Polianova
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MT
National Center of Infectious and Parasitic Diseases, Central AIDS Laboratory, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Jordanova
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PK
D000818:Animals; D001358:Avian Sarcoma Viruses; D002869:Chromosome Aberrations; D007621:Karyotyping; D015688:Oncogene Protein pp60(v-src) / Q000032:analysis*; D051381:Rats; D012513:Sarcoma, Experimental / Q000235:genetics*; D014407:Tumor Cells, Cultured
D015688:Oncogene Protein pp60(v-src)