[Reaction of umbilical cord arteries to PGF2 alpha and glycerol trinitrate during the first days post partum].
OBJECTIVE
Are there changes in the reactivity of umbilical cord arteries within the first day after parturition?


METHODS
Groups of rings made from umbilical cord arteries were investigated by a force transducer for their reactions to PGF2 alpha and glycerol trinitrate after 1, 6, 12 and 24 hours after parturition.


RESULTS
PGF2 alpha induces vasoconstriction, glycerol trinitrate vasodilatation of the umbilical cord arteries. The quantity of these reactions remains the same at each of the investigation times. But the standard deviation decreases 12 and 24 hours after parturition.


CONCLUSIONS
There is an increase of the reproducibility of these investigations in the second half of the first day after parturition. The higher standard deviation in the first 6 hours after parturition may be caused by endogenous autacoids.
Bartels
U
U
Universitäts-Frauenklinik Göttingen.
Meyer
S
S
Pündmann
I
I
Rath
W
W
Fleckenstein
G
G
Osmers
R
R
Kuhn
W
W
D012898:Autacoids / Q000502:physiology; D015237:Dinoprost / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D005996:Nitroglycerin / Q000494:pharmacology*; D010120:Oxytocics / Q000494:pharmacology*; D049590:Postpartum Period / Q000502:physiology; D011247:Pregnancy; D014469:Umbilical Arteries / Q000187:drug effects*; D014655:Vascular Resistance / Q000187:drug effects*; D014665:Vasodilator Agents / Q000494:pharmacology*
D012898:Autacoids; D010120:Oxytocics; D014665:Vasodilator Agents; D015237:Dinoprost; D005996:Nitroglycerin
Reaktion der Nabelschnurarterien auf PGF2 alpha und Glyzerol-trinitrat innerhalb des ersten Tages post partum.