Recurrent Goodpasture's disease.
Goodpasture's disease is usually a monophasic illness that can be successfully treated in a large proportion of patients. Recurrent disease is rare. We report a case of Goodpasture's disease in which recurrent pulmonary hemorrhage and glomerulonephritis were observed over 12 years. Antiglomerular basement membrane autoantibody was monitored throughout this period, and we demonstrate the close association of antibody levels with disease recurrence.
Levy
J B
JB
Renal Unit, Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom.
Lachmann
R H
RH
Pusey
C D
CD
D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis* / Q000473:pathology; D000906:Antibodies / Q000097:blood; D001323:Autoantibodies; D001485:Basement Membrane / Q000276:immunology; D001706:Biopsy; D002908:Chronic Disease; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000473:pathology; D007678:Kidney Glomerulus / Q000276:immunology; D008297:Male; D012008:Recurrence
D000906:Antibodies; D001323:Autoantibodies; C051951:antiglomerular basement membrane antibody