title: The effect of ethanol upon early development in mice and rats. XXII. The effect of chronic consumption of nonalcoholic beer upon preimplantation development in rats.
abstract: The effect upon preimplantation development of chronic consumption of nonalcoholic beer was investigated in rats (controlled on day 5 of pregnancy) by using the following criteria: mean number of embryos/animal, oviductal-uterine migration of embryos, developmental rate and number of pathologically modified embryos. It resulted that this beverage had a noxious effect (less marked than normal beer) upon preimplantation development, manifested by the decrease of the mean number of embryos/animal and the presence of abnormal embryos. These results suggest a possible action of various congeners present in this beverage, which potentiate the noxious effect of ethanol in the case of normal beer.
authors.affiliation: Laboratory of Embryology and Teratology, Center of Medicine and Sanitary Services and Management, Timisoara, Romania.
authors.forename: I
authors.initials: I
authors.lastname: Fazakas-Todea
mesh_terms: D000818:Animals; D001515:Beer / Q000009:adverse effects*; D047108:Embryonic Development; D005314:Embryonic and Fetal Development; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000431:Ethanol