title: Home treatment of patients with cystic fibrosis using the 'Intermate': the first year's experience.
abstract: Home treatment of patients with cystic fibrosis has many attractions and is becoming increasingly popular. The investigators have studied the use, results and costs of the first year of operation of a home-care intravenous antibiotic service using the 'Intermate' infusion device in a prospective study using questionnaires, spirometric and weight measurements. Ninety-three patients received 166 courses of intravenous antibiotics in full or in part at home during 1991. The average length of treatment was 12.5 days and on average 70% of the treatment was given at home. The mean percentage predicted FEV1 and FVC improved after treatment and the mean improvement was not significantly different to that produced by hospital treatment. Breathlessness, sputum volume, appetite, ability to sleep, mood, energy and overall well-being, as assessed by questionnaire, showed significant improvements after home treatment. The median time spent mixing and administering drugs was 10-19 hours and visiting the hospital was 7-12 hours. The median number of days of lost income to patients or their carers was 0 days. The majority of the patients were extremely satisfied with the treatment and supervision that they received. Using the home care service, 1442 inpatient days were saved. The investigators conclude that home care using 'Intermates' improves a patient's lung function and quality of life.
authors.affiliation: Department of Cystic Fibrosis, Royal Brompton Hospital, London.
authors.forename: E C
authors.initials: EC
authors.lastname: Bramwell
authors.forename: D M
authors.initials: DM
authors.lastname: Halpin
authors.forename: F
authors.initials: F
authors.lastname: Duncan-Skingle
authors.forename: M E
authors.initials: ME
authors.lastname: Hodson
authors.forename: D M
authors.initials: DM
authors.lastname: Geddes
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002648:Child; D003550:Cystic Fibrosis / Q000188:drug therapy*; D005260:Female; D005541:Forced Expiratory Volume; D017048:Health Care Costs; D006699:Home Care Services / Q000458:organization & administration*; D018718:Home Infusion Therapy / Q000191:economics / Q000295:instrumentation*; D006801:Humans; D008131:London; D008297:Male; D017063:Outcome Assessment, Health Care; D017060:Patient Satisfaction; D011446:Prospective Studies; D011788:Quality of Life
chemical_list: D000900:Anti-Bacterial Agents