[A case of the successful treatment of a patient with severe craniocerebral trauma combined with hemophilia].
The described case with a severe craniocerebral injury in a patient with hemophilia A demonstrated that the initial hypocoagulation does not preclude the development of intravascular blood coagulation. Therefore, in patients with severe brain injury, a more rapid reduction of antihemophilic globulin A is possible, in comparison with that occurring during planned surgery, and, hence, higher doses of cryoprecipitate and longer duration of its infusion are needed. Moreover, this case demonstrated that even in patients with a slight form of hemophilia A the treatment with cryoprecipitate should be continued till the levels of thrombinemia markers are reduced and the concentration of antihemophilic globulin A in the blood stabilized at a level of at least 10%; the dose of infused cryoprecipitate should be reduced gradually.
Churliaev
Iu A
IuA
Epifantseva
N N
NN
Karpenko
V S
VS
Chesnokov
D N
DN
Pavlenko
A A
AA
Rog
N M
NM
D000328:Adult; D001930:Brain Injuries / Q000097:blood / Q000150:complications / Q000601:surgery*; D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology / Q000628:therapy; D004630:Emergencies; D006467:Hemophilia A / Q000097:blood / Q000150:complications* / Q000628:therapy; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D011182:Postoperative Care; D011183:Postoperative Complications / Q000097:blood / Q000209:etiology / Q000628:therapy
Sluchaĭ uspeshnogo lecheniia bol'nogo s tiazheloĭ cherepno-mozgovoĭ travmoĭ v sochetanii s gemofilieĭ.