title: [The immediate and midterm results of percutaneous mitral valvuloplasty in subjects over 60].
abstract: We have analyzed the immediate and mid-term (1 and 2 years) results of percutaneous mitral valvuloplasty (PMV) by Inoue's catheter in 97 patients < 60 years (Group A) compared with 34 patients > 60 years (Group B). In 61% Group A the patients were in NYHA functional class II, 36% in III, and 3% in I; in Group B, 56% of the patients were in NYHA functional class III, 38% in II, and 6% in IV. Mean mitral valve area was 1.1 cm2 before dilatation in both groups, and a significant (p < 0.0001) increase was obtained in both Group A (0.9 +/- 0.3 cm2) and Group B (0.8 +/- 0.3 cm2). No significant differences were observed between the two groups. Mean transvalvular gradient decreased significantly (p < 0.0001) from 13.6 +/- 5.7 to 7.2 +/- 3.1 mmHg in Group A, and from 9.9 +/- 4 to 6.5 +/- 2.3 mmHg in Group B (A vs B: p < 0.02). Optimal result was obtained in 94% and 88% of Group A and Group B patients, respectively. Suboptimal result was obtained in 2% and 6% of Group A and Group B patients, respectively. These differences were not significant. Failure of PMV occurred in 4% and 6%, respectively. At 1-year follow-up Group A 7 patients and 5 Group B patients showed restenosis; at 2-year follow-up one more restenosis was present in Group A (A vs B at 1 and 2 years: NS). We conclude that PMV is a safe and effective technique in young patients and in patients > 60 years.
authors.affiliation: Instituto di Cardiologia, Università degli Studi, Catania.
authors.forename: C
authors.initials: C
authors.lastname: Tamburino
authors.forename: G
authors.initials: G
authors.lastname: Russo
authors.forename: R
authors.initials: R
authors.lastname: Foti
authors.forename: E
authors.initials: E
authors.lastname: Bonanno
authors.forename: W
authors.initials: W
authors.lastname: Deste
authors.forename: S
authors.initials: S
authors.lastname: Felis
authors.forename: A
authors.initials: A
authors.lastname: Passaniti
authors.forename: V
authors.initials: V
authors.lastname: Calvi
authors.forename: C E
authors.initials: CE
authors.lastname: Fiore
authors.forename: G
authors.initials: G
authors.lastname: Giuffrida
mesh_terms: D000328:Adult; D000368:Aged; D002404:Catheterization / Q000295:instrumentation / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000503:physiopathology; D008946:Mitral Valve Stenosis / Q000503:physiopathology / Q000628:therapy; D012008:Recurrence; D012214:Rheumatic Heart Disease / Q000503:physiopathology / Q000628:therapy; D018709:Statistics, Nonparametric; D013997:Time Factors
vernacular_title: Risultati immediati e a medio termine della valvuloplastica mitralica percutanea in soggetti di età > 60 anni.