Bone marrow transplantation in a thalassemia patient with congenital heart disease.
We report a thalassemia patient suffering from congenital transposition of the great arteries, surgically corrected according to Mustard technique at the age of 4 months, who underwent bone marrow transplantation. Despite a syncopal episode occurring during the first day after marrow infusion the transplant was successful. Thirty-two months later, normalization of hematologic parameters was observed together with a substantial improvement in cardiac function.
Baronciani
D
D
Divisione Ematologica e Centro Trapianto Midollo Osseo di Muraglia, Italy.
Angelucci
E
E
Agostinelli
F
F
Mariotti
E
E
Baldassarri
M
M
Martinelli
F
F
Lacerra
G
G
Lucarelli
G
G
D016026:Bone Marrow Transplantation; D005260:Female; D006801:Humans; D013789:Thalassemia / Q000503:physiopathology / Q000628:therapy*; D014188:Transposition of Great Vessels / Q000503:physiopathology*