Serum zinc and copper levels in sickle cell anaemia and beta-thalassaemia in North Jordan.
Serum zinc and copper levels were determined in 28 beta-thalassaemia and 15 sickle cell anaemia (SCA) patients of 3-10 years of age using atomic absorption spectrophotometry. The results were compared with 25 age-matched controls. Copper levels were significantly increased in beta-thalassaemia and sickle cell anaemia. Zinc levels were significantly increased in beta-thalassaemia but significantly decreased in SCA. The data suggest the occurrence of impaired kidney function and disturbance in the metabolism of zinc and copper in these patients.
Bashir
N A
NA
Department of Physiology and Biochemistry, Jordan University of Science and Technology, Irbid.
D000755:Anemia, Sickle Cell / Q000097:blood*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003300:Copper / Q000097:blood*; D006801:Humans; D007597:Jordan; D013054:Spectrophotometry, Atomic; D015032:Zinc / Q000097:blood*; D017086:beta-Thalassemia / Q000097:blood*
D003300:Copper; D015032:Zinc