[Comparative testing of live measles vaccines manufactured in France, Japan, and Russia].
Live measles vaccines prepared from different strains in France, Japan, and Russia were compared at the L. A. Tarasevich State Institute for Standardization and Control of Viral Preparations. Clinical reactions to the tested vaccines were studied in 181 children seronegative before vaccination. Vaccinal reactions to French, Japanese, and Russian were observed in 24.2, 26.5, and 5.9% vaccinees, respectively. The French and Russian vaccines virtually did not differ by the level of seroconversion (96 and 98.1%, respectively). For the Japanese vaccine the level of sero-conversion was lower: 91.6%. The mean titers of antibodies in vaccinees immunized with the French, Japanese, and Russian vaccines were, respectively, 7.36 +/- 0.91, 2.07 +/- 0.42, and 4.40 +/- 0.42 IU.
Popov
V F
VF
Iunasova
T N
TN
Povalikhina
L V
LV
Shitikova
O Iu
OIu
D000914:Antibodies, Viral / Q000096:biosynthesis / Q000097:blood; D002675:Child, Preschool; D005602:France; D006801:Humans; D007564:Japan; D008458:Measles Vaccine / Q000009:adverse effects / Q000276:immunology / Q000592:standards*; D012426:Russia
D000914:Antibodies, Viral; D008458:Measles Vaccine
Sravnitel'nye ispytaniia zhivykh korevykh vaktsin proizvodstva Frantsii, Iaponii i Rossii.