title: Comparison of exercise stress testing with simultaneous dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computerized tomography for diagnosis of coronary artery disease.
abstract: The object of our study was to compare the value of exercise stress testing with simultaneous dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computed tomography for the diagnosis of coronary artery disease. Sixty-nine patients with either suspected or proven coronary artery disease underwent simultaneous dobutamine technetium-99m isonitrile single-photon emission computed tomography and stress echocardiography, and treadmill exercise electrocardiography. Dobutamine echocardiography and technetium-99m isonitrile single-photon emission computed tomography revealed a higher overall sensitivity than exercise testing (94 vs 60%, P < 0.001), but dobutamine stress echocardiography showed a higher specificity than both technetium-99m isonitrile single-photon emission computed tomography and exercise testing (86 vs 64%, P < 0.05, for both tests). In addition, the diagnostic accuracy of dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computed tomography was higher than that of exercise testing (91 vs 61%, P < 0.001; 86 vs 61%, P < 0.001, respectively). Dobutamine stress echocardiography and technetium-99m isonitrile single-photon emission computed tomography are superior to exercise testing in the diagnosis of coronary artery disease, and dobutamine stress echocardiography can act as an alternative to technetium-99m isonitrile single-photon emission computed tomography.
authors.affiliation: Department of Cardiology, Ankara Yüksek Ihtisas Hospital, Turkey.
authors.forename: H L
authors.initials: HL
authors.lastname: Kisacik
authors.forename: K
authors.initials: K
authors.lastname: Ozdemir
authors.forename: E
authors.initials: E
authors.lastname: Altinyay
authors.forename: A
authors.initials: A
authors.lastname: Oğuzhan
authors.forename: T
authors.initials: T
authors.lastname: Kural
authors.forename: M
authors.initials: M
authors.lastname: Kir
authors.forename: E
authors.initials: E
authors.lastname: Kütük
authors.forename: S
authors.initials: S
authors.lastname: Göksel
mesh_terms: D000328:Adult; D000368:Aged; D002316:Cardiotonic Agents; D003287:Contrast Media; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis* / Q000503:physiopathology; D004280:Dobutamine; D004452:Echocardiography / Q000187:drug effects; D004562:Electrocardiography / Q000187:drug effects; D005080:Exercise Test / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D002316:Cardiotonic Agents; D003287:Contrast Media; D004280:Dobutamine; D017256:Technetium Tc 99m Sestamibi