Assessment of protein intake in children with chronic renal insufficiency.
Daily nitrogen intake was estimated in 19 children, aged (mean +/- SD) 9.9 +/- 5.0 (range: 1-19) years with chronic renal insufficiency (creatinine clearance 47.1 +/- 19.3 ml/min/1.73 m2, range: 11-75) by 31 three-day prospective dietary records (NIDR) and simultaneous 24-hour urine urea excretion (NIUE). Daily nitrogen intake was 11.05 +/- 3.9 g by NIDR and 8.52 +/- 3.3 g by NIUE, and a significant correlation (r = 0.61; p = 0.0003) existed between both methods of measurement. However, the difference in nitrogen intake estimated from dietary records and from 24-hour urine collection (NIDR-NIUE) was 2.5 +/- 3.3 g, greater than the mean estimated nitrogen intake calculated from both methods, (NIDR + NIUE)/2, 95% limits of agreement being +9.1 to -4.1. Thus, NIDR and NIUE values show a good correlation in children with chronic renal insufficiency, although both methods may provide quite a different estimation in a given child.
Orejas
G
G
Division of Pediatric Nephrology, Hospital Central de Asturias, University of Oviedo, Spain.
Santos
F
F
Málaga
S
S
Cobo
A
A
Rey
C
C
Martínez
V
V
D000293:Adolescent; D000328:Adult; D001806:Blood Urea Nitrogen; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000378:metabolism; D015930:Diet Records; D004044:Dietary Proteins; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000503:physiopathology*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D014508:Urea / Q000652:urine
D004044:Dietary Proteins; D014508:Urea; D003404:Creatinine; D009584:Nitrogen