Arabidopsis AUX1 gene: a permease-like regulator of root gravitropism.
The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid-like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.
Bennett
M J
MJ
Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK.
Marchant
A
A
Green
H G
HG
May
S T
ST
Ward
S P
SP
Millner
P A
PA
Walker
A R
AR
Schulz
B
B
Feldmann
K A
KA
D015084:2,4-Dichlorophenoxyacetic Acid / Q000494:pharmacology; D000595:Amino Acid Sequence; D026905:Amino Acid Transport Systems; D000596:Amino Acids / Q000378:metabolism; D017360:Arabidopsis / Q000737:chemistry / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D029681:Arabidopsis Proteins; D001692:Biological Transport; D003001:Cloning, Molecular; D004269:DNA, Bacterial / Q000235:genetics; D017343:Genes, Plant; D005816:Genetic Complementation Test; D018522:Gravitropism; D007210:Indoleacetic Acids / Q000378:metabolism / Q000494:pharmacology; D026901:Membrane Transport Proteins / Q000737:chemistry; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009154:Mutation; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D018517:Plant Roots / Q000254:growth & development* / Q000378:metabolism; D016415:Sequence Alignment; D015398:Signal Transduction
C100794:AUX1 protein, Arabidopsis; D026905:Amino Acid Transport Systems; D000596:Amino Acids; D029681:Arabidopsis Proteins; D004269:DNA, Bacterial; D007210:Indoleacetic Acids; D026901:Membrane Transport Proteins; D010940:Plant Proteins; C036483:T-DNA; D015084:2,4-Dichlorophenoxyacetic Acid; C030737:indoleacetic acid