Six trigalactosylceramides from the leech (Hirudo nipponica).
Six neutral glycosphingolipids were isolated in the pure state from the leech, Hirudo nipponica (Annelida). In contrast to the zwitterionic monogalactosylceramides carrying a choline phosphate group so far obtained, all compounds are non-zwitterionic glycosphingolipids, trigalactosylceramides. Five compounds possess a Ga1 alpha 1-6Ga1 alpha 1-6Ga1 beta 1-Cer core, and one is unique in having a Ga1 alpha 1-6Ga1 beta 1-Cer structure. Their full structures have been determined on the bases of chemical and spectral evidence.
Noda
N
N
Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.
Tanaka
R
R
Miyahara
K
K
Sukamoto
T
T
D000818:Animals; D002240:Carbohydrate Sequence; D005699:Galactosylceramides / Q000737:chemistry / Q000302:isolation & purification*; D007865:Leeches / Q000737:chemistry*; D008969:Molecular Sequence Data; D016339:Spectrometry, Mass, Fast Atom Bombardment
D005699:Galactosylceramides