title: Budd-Chiari syndrome attributed to protein C deficiency.
abstract: The protein C anticoagulant pathway is an important downregulating mechanism of the blood coagulation cascade. We report a 47-yr-old male with Budd-Chiari syndrome and occlusion of the inferior vena cava. His plasma protein C antigen level was decreased to 42%, and its activity was 34%. Other coagulable factors were normal. Protein C deficiency should be considered a possible etiological factor of the Budd-Chiari syndrome.
authors.affiliation: Department of Internal Medicine, Gastroenterology/Hepatology Division, Saiseikai Wakakusa Hospital, Yokohama, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Sugano
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Makino
authors.forename: S
authors.initials: S
authors.lastname: Yanagimoto
authors.forename: M
authors.initials: M
authors.lastname: Nishio
authors.forename: H
authors.initials: H
authors.lastname: Onmura
authors.forename: M
authors.initials: M
authors.lastname: Iinuma
authors.forename: T
authors.initials: T
authors.lastname: Matuda
authors.forename: Y
authors.initials: Y
authors.lastname: Shinozawa
mesh_terms: D000437:Alcoholism / Q000150:complications; D006502:Budd-Chiari Syndrome / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020151:Protein C Deficiency; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology; D014682:Vena Cava, Inferior