title: Differential expression of AF4/FEL mRNA in human tissues.
abstract: This manuscript reports the differential expression of the AF4 gene among human tissues. AF4 mRNA is highly expressed in normal placental tissue which correlates with the newborn age of patients presenting with leukemia characterized by the MLL/AF4 gene rearrangement.
authors.affiliation: Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis 55455, USA. frest001@maroon.tc.umn.edu
authors.forename: J L
authors.initials: JL
authors.lastname: Frestedt
authors.forename: J M
authors.initials: JM
authors.lastname: Hilden
authors.forename: R O
authors.initials: RO
authors.lastname: Moore
authors.forename: J H
authors.initials: JH
authors.lastname: Kersey
mesh_terms: D001483:Base Sequence; D015152:Blotting, Northern; D018076:DNA, Complementary; D004268:DNA-Binding Proteins / Q000235:genetics*; D015870:Gene Expression; D006801:Humans; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000235:genetics*; D010920:Placenta / Q000378:metabolism; D012333:RNA, Messenger; D014018:Tissue Distribution; D035602:Transcriptional Elongation Factors
chemical_list: D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D012333:RNA, Messenger; D035602:Transcriptional Elongation Factors; C081449:AFF1 protein, human