title: [Human gonadal hilar cells--histogenesis, differentiation, role].
abstract: Identification hilar cells in fetus and adult gonads two sex and dysgenetic gonads were based on histochemical and immunohistochemical methods. The hilar cells were detected in 40% of fetus gonads (ovarian testis), two time more in adult and dysgenetic gonads. The attention was put to their connection with nervous system. On the bases of specific markers there was established their mesenchymal origin, ability to response to gonadotropin induction and synthetization steroid hormones, mainly androgens. Hilar cells in dysgenetic gonads and postmenopausal women may be responsible for clinical manifestation of virilisation.
authors.affiliation: Instytutu Pediatrii, III Kliniki Chorób Dzieci AM w Poznaniu.
authors.forename: A
authors.initials: A
authors.lastname: Kedzia
authors.forename: A
authors.initials: A
authors.lastname: Warenik-Szymankiewicz
authors.forename: H
authors.initials: H
authors.lastname: Kedzia
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005333:Fetus / Q000166:cytology; D006059:Gonadal Dysgenesis / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010063:Ovum / Q000166:cytology* / Q000254:growth & development / Q000502:physiology; D017698:Postmenopause / Q000502:physiology; D013094:Spermatozoa / Q000166:cytology* / Q000254:growth & development / Q000502:physiology; D014770:Virilism / Q000503:physiopathology
vernacular_title: Komórki wnekowe gonad ludzkich--pochodzenie, róznicowanie, rola.