title: [Carcinoid tumors in Denmark 1978-1989 and the risk of development of new cancers].
abstract: Previous studies have suggested an excess cancer risk in patients with carcinoid tumours. We re-examined this association by the use of truly population-based data from the Danish Cancer Register. One thousand and twenty-nine patients with carcinoid tumours diagnosed in Denmark 1978-89 were identified and followed for the occurrence of subsequent cancers. The ratio of observed to expected cancers calculated from population rates served as a measure of the relative cancer risk (RR). The annual age-adjusted incidence rate for carcinoid tumours was 1.1 per 100,000 person-years (world standardized). The overall relative risk of subsequent cancers was 1.1 (95% CI 0.8-1.6). Thyroid cancer, tumours of the brain and nervous system and non-Hodgkin's lymphomas were in excess. Overall, this study does not support previous findings of a general excess cancer risk in patients with carcinoid tumors. Significantly increased risks of cancer were observed at some sites, but these findings were based on small numbers, and consequently need further confirmation.
authors.affiliation: Center for epidemiologisk grundforskning, Statens Seruminstitut, København.
authors.forename: T
authors.initials: T
authors.lastname: Westergaard
authors.forename: M
authors.initials: M
authors.lastname: Frisch
authors.forename: M
authors.initials: M
authors.lastname: Melbye
mesh_terms: D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000453:epidemiology*; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000209:etiology*; D012042:Registries; D012307:Risk Factors
vernacular_title: Karcinoide tumorer i Danmark 1978-1989 og risikoen for udvikling af nye cancere.