[Clinical, biological and developmental aspects of alcoholic ketoacidosis].
OBJECTIVE
To review cases of alcoholic ketoacidosis in order to better ascertain therapeutic management.


METHODS
The medical files of 32 alcoholic patients with ketoacidosis hospitalized in the Saint-Pierre general hospital of the Reunion island from January 1, 1991 through 31 August 1994 were analyzed.


RESULTS
There were 18 women and 14 men, mean age 47 years. The first clinical signs were predominated by digestive (n = 22) or neurological disorders (n = 10). Acidosis was severe (mean pH = 7.12) and always associated with a wide anion gap (mean anion gap = 35). There were 3 types of glycemic status: hypoglycemia 10 cases, normal or subnormal glycemia in 19 cases (mean glycemia = 9.3 mmol/l) and hyperglycemia above 20 mmol/l in 3 cases. Hypophosphatemia, elevated serum lactate levels and cytolytic hepatitis were the main abnormalities associated.


CONCLUSIONS
Short-term outcome was favorable in all cases after rehydration. The use of insulin may be dangerous and needs to be avoided.
Gaches
F
F
Service de Médecine B, Centre Hospitalier Général de Saint-Pierre de La Réunion.
Freneau
E
E
Le Gall
S
S
Le Moullec
N
N
Evrin
M
M
Schwager
J C
JC
D000138:Acidosis / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006760:Hospitalization; D006801:Humans; D007662:Ketosis / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D013997:Time Factors
Aspects cliniques, biologiques et évolutifs de l'acidocétose alcoolique.