[Indication of hepatitis C virus antibodies with separation into IgM and IgG classes and its clinical significance].
A method for indication of anti-HCV antibodies with separation into IgM and IgG has been developed. Trials of the method in 182 patients with hepatitis C confirmed its value for the differentiation between acute and chronic forms of the disease. Antibodies of both classes were found in patients with acute hepatitis C, and the titer of IgG anti-HCV increased as the disease progressed. In chronic infection the level of anti-HCV IgG was stable, and there were no early antibodies. Appearance of anti-HCV IgM in chronic forms corresponded to exacerbation of the infectious process.
Afanas'ev
A Iu
AIu
D003937:Diagnosis, Differential; D016174:Hepacivirus / Q000276:immunology*; D006526:Hepatitis C / Q000175:diagnosis* / Q000276:immunology; D018937:Hepatitis C Antibodies / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*
D018937:Hepatitis C Antibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Indikatsiia antitel k virusu gepatita C s razdeleniem na klassy IgM i IgG i ee klinicheskoe znachenie.