title: Effect of pneumoperitoneum and Trendelenburg position on gastro-oesophageal reflux and lower oesophageal sphincter pressure.
abstract: We have measured the effect of pneumoperitoneum and the Trendelenburg position on lower oesophageal sphincter (LOSP) and barrier pressures (BrP) in 11 anaesthetized pigs while measuring the incidence of gastro-oesophageal reflux with a pH electrode. Propofol in combination with sufentanil had no effect on LOSP or BrP. Adoption of the Trendelenburg position with a pneumoperitoneum of 15 mm Hg resulted in a significant increase in LOSP (P < 0.002) and BrP (P < 0.001). However, in two of 11 pigs who had the lowest LOSP before induction, there was regurgitation.
authors.affiliation: Service d'Anesthésie-Réanimation, Hôpital de l'Hôtel-Dieu, Lyon, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Tournadre
authors.forename: D
authors.initials: D
authors.lastname: Chassard
authors.forename: K R
authors.initials: KR
authors.lastname: Berrada
authors.forename: P
authors.initials: P
authors.lastname: Bouletreau
mesh_terms: D000768:Anesthesia, General; D000818:Animals; D004943:Esophagogastric Junction / Q000503:physiopathology*; D005764:Gastroesophageal Reflux / Q000503:physiopathology*; D008365:Manometry; D011028:Pneumoperitoneum, Artificial; D011187:Posture; D011312:Pressure; D013552:Swine