title: Erythropoietin treatment of erythropoietin-deficient anemia without renal disease during pregnancy.
abstract: BACKGROUND
  The use of recombinant human erythropoietin in pregnancy has been described in patients with renal impairment. We present a patient with a hypoproliferative anemia with low serum erythropoietin levels and no renal disease or other known cause for this type of anemia, who was treated with recombinant human erythropoietin.
  
  
  METHODS
  A 29-year-old white woman who became pregnant after leuprolide acetate and menopausal gonadotropin therapy developed a moderate anemia (hemoglobin 8.5 g/dL) in early pregnancy. The only important laboratory findings were a hypoproliferative marrow and a low serum erythropoietin level. She was treated successfully with injections of recombinant human erythropoietin. Her pregnancy was otherwise uncomplicated and her pre-delivery hemoglobin level was 12 g/dL.
  
  
  CONCLUSIONS
  Hypoproliferative anemia in pregnancy with low erythropoietin levels and no renal disease can be treated successfully with recombinant human erythropoietin.
authors.affiliation: Division of Maternal-Fetal Medicine, Baylor University Medical Center, Dallas, Texas, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Harris
authors.forename: G
authors.initials: G
authors.lastname: Payne
authors.forename: J M
authors.initials: JM
authors.lastname: Putman
mesh_terms: D000328:Adult; D000740:Anemia / Q000188:drug therapy*; D004921:Erythropoietin / Q000172:deficiency* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007674:Kidney Diseases; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011256:Pregnancy Outcome; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin