title: Migraine: definitions, mechanisms, and treatment.
abstract: Although ubiquitous, migraine remains incompletely understood and thus often ineffectively managed. Fortunately, new advances in our understanding of migraine's origins have led to identification and application of therapeutic intervention that is unparalleled in its specificity and clinical efficacy. We present a unified model of migraine genesis and explain how application of the model to clinical practice may improve therapeutic management of this common disorder.
authors.affiliation: Department of Neurology, University of California, San Diego, USA.
authors.forename: H
authors.initials: H
authors.lastname: Noack
authors.forename: J F
authors.initials: JF
authors.lastname: Rothrock
mesh_terms: D002560:Cerebrovascular Circulation; D005260:Female; D017048:Health Care Costs; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000191:economics / Q000209:etiology / Q000503:physiopathology; D008959:Models, Neurological; D015995:Prevalence