Development of complete heart block in an adult patient with Sjögren's syndrome and anti-Ro/SS-A autoantibodies.
We describe the occurrence of complete heart block in a patient with Sjögren's syndrome. The patient's serum contained antibodies to both the 60-kd and 52-kd Ro proteins. This case indicates that although the adult atrioventricular node may be relatively resistant to the development of anti-Ro-associated heart block, it can nevertheless be affected.
Lee
L A
LA
Oklahoma Medical Research Foundation, Oklahoma City 73104, USA.
Pickrell
M B
MB
Reichlin
M
M
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood*; D005260:Female; D006327:Heart Block / Q000209:etiology*; D006801:Humans; D012307:Risk Factors; D012859:Sjogren's Syndrome / Q000150:complications* / Q000276:immunology
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies