title: [Prevention of polymorphous ventricular tachycardia in patients with congenital long QT interval syndrome].
abstract: Patients with the Romano-Ward long QT interval syndrome run a high risk of sudden cardiac death. Beta-blockers of the sympathetic nerve are effective treatment. Some patients die suddenly despite this treatment. The treatment of choice is a combination of beta-blockers of the sympathetic nerve and cardiostimulation. The authors describe a group of their own five patients from three families with the Romano-Ward syndrome. The course was favourable. The stimulation rate needed for normalization of the QT interval and a favourable clinical development was 78 +/- 6 imp./min. Based on data in the literature and their own experience the authors recommended combined treatment with beta-blockers and cardiostimulation in patients with the Romano-Ward syndrome, if monotherapy with beta-blockers is not effective.
authors.affiliation: Interná klinika A Nemocnice F.D. Roosevelta, Banská Bystrica.
authors.forename: G
authors.initials: G
authors.lastname: Kaliská
authors.forename: P
authors.initials: P
authors.lastname: Kmec
authors.forename: I
authors.initials: I
authors.lastname: Nedĕlová
authors.forename: M
authors.initials: M
authors.lastname: Szentivanyi
authors.forename: J
authors.initials: J
authors.lastname: Skamla
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000319:Adrenergic beta-Antagonists
vernacular_title: Moznosti prevencie polymorfnej komorovej tachykardie u pacientov s kongenitálnym syndrómom dlhého QT intervalu.