title: Biomembrane templates for nanoscale conduits and networks.
abstract: Long nanotubes of fluid-lipid bilayers can be used to create templates for photochemical polymerization into solid-phase conduits and networks. Each nanotube is pulled from a micropipette-held feeder vesicle by mechanical retraction of the vesicle after molecular bonding to a rigid substrate. The caliber of the tube is controlled precisely in a range from 20 to 200 nanometers merely by setting the suction pressure in the micropipette. Branched conduits can be formed by coalescing separate nanotubes drawn serially from the feeder vesicle surface. Single nanotubes and nanotube junctions can be linked together between bonding sites on a surface to create a functionalized network. After assembly, the templates can be stabilized by photoinitiated radical cross-linking of macromonomers contained in the aqueous solution confined by the lipid bilayer boundary.
authors.affiliation: Department of Physics, University of British Columbia, Vancouver, British Columbia, Canada V6T 1W5.
authors.forename: E
authors.initials: E
authors.lastname: Evans
authors.forename: H
authors.initials: H
authors.lastname: Bowman
authors.forename: A
authors.initials: A
authors.lastname: Leung
authors.forename: D
authors.initials: D
authors.lastname: Needham
authors.forename: D
authors.initials: D
authors.lastname: Tirrell
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D008051:Lipid Bilayers; D011092:Polyethylene Glycols
chemical_list: D008051:Lipid Bilayers; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols