[Importance of the expression of the C6 molecule on cells in chronic lymphatic leukemia].
The authors made immunophenotyping analyses of blood cells of 50 patients with the diagnosis of B-CLL. Malignant cells contained in all instances HLA DR and CD24 molecules. The superficial molecule CD5 was expressed on cells in 85.7% molecule CD6 on 66.7% cases. By statistical analysis the relationship between selected clinical parameters and expression of surface molecules CD5, CD6 and CD10 was sought. A statistically significantly higher number of leucocytes was found in patients with expression of molecule CD6.
Krejsek
J
J
II. Interní klinika LF UK, Hradec Králové.
Kopecký
O
O
Derner
V
V
Voglová
J
J
D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000032:analysis*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis*; D051927:CD24 Antigen; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D016130:Immunophenotyping; D015448:Leukemia, B-Cell / Q000276:immunology*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology*; D008297:Male; D008562:Membrane Glycoproteins; D008875:Middle Aged
D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D051927:CD24 Antigen; C497889:CD24 protein, human; C062279:CD6 antigen; D006684:HLA-DR Antigens; D008562:Membrane Glycoproteins
Význam exprese molekuly CD6 na bunkách chronické lymfatické leukémie.