Review: the effects of antihypertensive agents on serum lipids.
Because various antihypertensive drugs adversely affect lipid metabolism, these drugs may increase associated risks for coronary artery disease and thus offset some of the beneficial effects of blood pressure reduction. In this paper the current literature regarding the effects of antihypertensive agents on serum lipids is reviewed. Differing effects of various classes of antihypertensives are assessed to further our understanding of this very important subject.
Madu
E C
EC
Department of Medicine, University of Tennessee, Memphis 38163, USA.
Reddy
R C
RC
Madu
A N
AN
Anyaogu
C
C
Harris
T
T
Fraker
T D
TD
D058668:Adrenergic alpha-1 Receptor Antagonists; D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000494:pharmacology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000145:classification / Q000494:pharmacology*; D002121:Calcium Channel Blockers / Q000009:adverse effects / Q000494:pharmacology; D003327:Coronary Disease / Q000097:blood / Q000209:etiology; D004232:Diuretics / Q000009:adverse effects / Q000494:pharmacology; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D012307:Risk Factors
D058668:Adrenergic alpha-1 Receptor Antagonists; D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics; D008055:Lipids; D008074:Lipoproteins