title: Genetic variants of serum alpha 1 antitrypsin.
abstract: Complete absence of data on alpha 1 antitrypsin in this country prompted us to determine serum levels using radial immunodiffusion (RID) and phenotypes by isoelectric focusing (IEF) in 100 healthy adults (52 males and 48 females). Mean serum alpha 1 antitrypsin concentration in healthy subjects was 2.47 +/- 0.08 g/l and the main phenotypes MM (70%), M1 M2 (28%) and FM 3 (2%) are infrequent in our population.
authors.affiliation: PMRC Research Centre, Aga Khan University, Karachi.
authors.forename: A
authors.initials: A
authors.lastname: Shahid
authors.forename: A A
authors.initials: AA
authors.lastname: Siddiqui
authors.forename: S J
authors.initials: SJ
authors.lastname: Zuberi
authors.forename: M A
authors.initials: MA
authors.lastname: Waqar
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D014644:Genetic Variation; D006801:Humans; D005779:Immunodiffusion; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D015842:Serine Proteinase Inhibitors / Q000097:blood / Q000235:genetics*; D000515:alpha 1-Antitrypsin / Q000032:analysis / Q000235:genetics*
chemical_list: D015842:Serine Proteinase Inhibitors; D000515:alpha 1-Antitrypsin