[Clinical application of oncogene and antioncogene as a tumor marker].
Since it is generally accepted that neoplasm is developed by accumulation of abnormalities in oncogenes and antioncogenes, these genetic analysis would be useful as new tumor markers. The present clinical applications of genetic analysis of oncogenes are as follows, 1) diagnosis of neoplasm (early detection, differential diagnosis for borderline lesion), 2) speculation of the prognosis of a cancer patient and prediction of chemosensitivity and, 3) establishment of high risk group of cancer. In regard to clinical practice, a medical doctor take care of scientific interpretation of genetic examinations as well as ethical problems.
Kondo
H
H
Division of G1 oncology, National Cancer Center Hospital.
Nobuoka
A
A
D014408:Biomarkers, Tumor / Q000032:analysis*; D016147:Genes, Tumor Suppressor; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis; D009857:Oncogenes
D014408:Biomarkers, Tumor