title: MR magnetization transfer measurements in temporal lobe epilepsy: a preliminary study.
abstract: MR magnetization transfer ratio was measured in both hippocampi of three patients with temporal lobe epilepsy, and in two control subjects. The magnetization transfer ratio in each section was significantly lower on the affected side than on the contralateral side and in control subjects. Magnetization transfer ratio measurements are relatively fast and precise, this preliminary study shows that they may provide useful presurgical information.
authors.affiliation: NMR Research Unit, Institute of Neurology, Queen Square, London, United Kingdom.
authors.forename: P S
authors.initials: PS
authors.lastname: Tofts
authors.forename: S
authors.initials: S
authors.lastname: Sisodiya
authors.forename: G J
authors.initials: GJ
authors.lastname: Barker
authors.forename: S
authors.initials: S
authors.lastname: Webb
authors.forename: D
authors.initials: D
authors.lastname: MacManus
authors.forename: F
authors.initials: F
authors.lastname: Fish
authors.forename: S
authors.initials: S
authors.lastname: Shorvon
mesh_terms: D000328:Adult; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000473:pathology; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged