title: Sequestrectomy and local muscle flap implantation for chronic osteomyelitis in children and adolescents.
abstract: Forty one children and adolescents (mean age 11.9 years) with chronic osteomyelitis that were not previously managed surgically were prospectively studied during a 5-year period in the University of Calabar Teaching Hospital, Calabar, Nigeria. All cases were managed by sequestrectcomy of curretage and local muscle flap implantation into the space so created. Preoperative care in this series included blood transfusion for anaemic patients and augmentin (amoxycillin and clavulanic acid) while definitive antibiotic therapy depended on the antimicrobial sensitivity pattern of Staphylococcus aureus and Pseudomonas species which were the predominant bacterial isolates. Overall, the incidence of wound dehiscence and recurrence of chronic osteomyelitis were low (19.5%), and complete healing of all cases occurred by two years of follow-up. The major complications were joint stiffness, limb shortening and pathological fractures.
authors.affiliation: Department of Surgery/Othorpaedics, University of Calabar, Teaching Hospital, Nigeria.
authors.forename: L O
authors.initials: LO
authors.lastname: Bassey
authors.forename: O E
authors.initials: OE
authors.lastname: Antia-Obong
authors.forename: U E
authors.initials: UE
authors.lastname: Antia
mesh_terms: D000293:Adolescent; D000658:Amoxicillin / Q000627:therapeutic use; D019980:Amoxicillin-Potassium Clavulanate Combination; D019072:Antibiotic Prophylaxis; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D002969:Clavulanic Acids / Q000627:therapeutic use; D003646:Debridement / Q000379:methods; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000601:surgery*; D011446:Prospective Studies; D011859:Radiography; D013524:Surgical Flaps / Q000379:methods; D016896:Treatment Outcome
chemical_list: D002969:Clavulanic Acids; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin