Comparison of agonist potencies at human dopamine D2 and D3 receptors, expressed in the same cell line, using the Cytosensor Microphysiometer.
Boyfield
I
I
Psychiatry Research Department, SmithKline Beacham Pharmaceuticals, Harlow, Essex, U.K.
Winn
F
F
Coldwell
M
M
D000818:Animals; D016466:CHO Cells; D005576:Colforsin / Q000494:pharmacology; D006224:Cricetinae; D000242:Cyclic AMP / Q000378:metabolism; D018491:Dopamine Agonists / Q000378:metabolism* / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D011869:Radioligand Assay; D017448:Receptors, Dopamine D2 / Q000378:metabolism / Q000502:physiology*; D050637:Receptors, Dopamine D3; D011994:Recombinant Proteins / Q000378:metabolism; D013329:Structure-Activity Relationship; D014162:Transfection
C493593:DRD3 protein, human; D018491:Dopamine Agonists; D017448:Receptors, Dopamine D2; D050637:Receptors, Dopamine D3; D011994:Recombinant Proteins; D005576:Colforsin; D000242:Cyclic AMP