Agglutinins for brucellae antigens in blood sera of an urban and rural population in Kenya.
The antibody titres for Brucella arbotus and Br. melitensis in 364 sera from healthy individuals in Nairobi and Naivasha are presented. A majority (96%) had no detectable agglutinins. Reactivity was markedly higher in the Naivasha serum samples, than in those from Nairobi. In Naivasha, seven per cent showed reactivity, whereas in Nairobi a larger majority (98%), showed no reactivity, with antibody titres ranging from 1:20-1:160. Age and sex were found to have no effect on antibody titre distribution in the two populations. The presence of brucellae antibodies in the healthy population screened (with titres upto 1:80) may be due to exposure to brucellae antigens, rather than denoting brucellosis, this titre could therefore be taken as the baseline in the healthy Kenyan population.
Jumba
M M
MM
National Public Health Laboratories, Nairobi.
Mirza
N B
NB
Mwaura
F B
FB
D000293:Adolescent; D000328:Adult; D000372:Agglutination Tests / Q000592:standards*; D000942:Antigens, Bacterial / Q000097:blood*; D002003:Brucella abortus / Q000276:immunology*; D017347:Brucella melitensis / Q000276:immunology*; D002648:Child; D005260:Female; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D008297:Male; D008403:Mass Screening; D011159:Population Surveillance; D012016:Reference Values; D012423:Rural Health; D016036:Seroepidemiologic Studies; D014504:Urban Health
D000942:Antigens, Bacterial