[Several indicators of lipids, blood hormones and T-cell unit of the immune system in mice with increased body mass at distant periods after local irradiation of the thymus, hypothalamus-hypophysis and gonads].
In hybrid mice it was shown that the local irradiation of zones of thymus, hypothalamus-hypophysis (0.5, 1 and 10 Gy in both cases) and gonads (10 Gy) resulted in significant increase in weight at long terms after irradiation. In animals with increased weight the amount of lipids raised, balance of hormones and state of thymus-dependent unit of immune system changed, and exterior symptoms of early aging were observed. After irradiation of spleen and thigh muscles (10 Gy in both cases) all indices at the same period corresponded to age control.
Savina
N P
NP
D'iakova
A M
AM
Liasko
L I
LI
D000375:Aging; D000818:Animals; D013006:Growth Hormone / Q000097:blood; D006728:Hormones / Q000097:blood*; D006854:Hydrocortisone / Q000097:blood; D007031:Hypothalamus / Q000528:radiation effects*; D008055:Lipids / Q000097:blood*; D008297:Male; D051379:Mice; D010902:Pituitary Gland / Q000528:radiation effects*; D011829:Radiation Dosage; D013154:Spleen / Q000528:radiation effects; D013601:T-Lymphocytes / Q000528:radiation effects*; D013737:Testis / Q000528:radiation effects*; D013950:Thymus Gland / Q000528:radiation effects*; D015430:Weight Gain
D006728:Hormones; D008055:Lipids; D013006:Growth Hormone; D006854:Hydrocortisone
Nekotorye pokazateli lipidov, gormonov krovi, T-kletochnogo zvena immunnoĭ sistemy u mysheĭ s povyshennoĭ massoĭ tela v otdalennyĭ period posle lokal'nogo oblucheniia timusa, gipotalamusa-gipofiza i gonad.