title: Reaction of metallothionein with ethylenediamine-N,N,N',N'-tetraacetic acid.
abstract: The reactions of various rabbit MTs (Cd7Th, Zn7Th, Hg7Th, Bi7Th, Pb7Th) with EDTA were studied at different pH and EDTA concentrations, and were determined to be pseudo-first-order reactions. The reactions were all divided into two steps: one faster and EDTA-dependent, and the other EDTA-independent. The mechanism is also described in detail. Based on obtained results, the varied induction behaviors of MT formation for those metals are discussed.
authors.affiliation: State Key Laboratory of Coordination Chemistry, Nanjing University, People's Republic of China.
authors.forename: S
authors.initials: S
authors.lastname: Yue
authors.forename: W
authors.initials: W
authors.lastname: Zhong
authors.forename: B
authors.initials: B
authors.lastname: Zhang
authors.forename: L
authors.initials: L
authors.lastname: Zhu
authors.forename: W
authors.initials: W
authors.lastname: Tang
mesh_terms: D000818:Animals; D004492:Edetic Acid / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008668:Metallothionein / Q000737:chemistry* / Q000378:metabolism; D008670:Metals / Q000737:chemistry / Q000378:metabolism; D011817:Rabbits
chemical_list: D008670:Metals; D008668:Metallothionein; D004492:Edetic Acid