[Pharmacology of Catharanthus alkaloids].
Catharanthus alkaloids are antitumoral drugs widely used in the treatment of malignant diseases. This review summarizes different aspects of their pharmacology (mechanism of action, resistance, clinical pharmacokinetics) as well as information on their uses in the clinical setting.
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Laboratoire de pharmacocinétique, Institut de Bactériologie, Strasbourg, France.
Wihlm
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Jehl
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D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology*; D004347:Drug Interactions; D004361:Drug Tolerance; D006801:Humans; D014747:Vinblastine / Q000031:analogs & derivatives / Q000494:pharmacology; D014748:Vinca Alkaloids / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology*; D014750:Vincristine / Q000494:pharmacology; D014751:Vindesine / Q000494:pharmacology; D000077235:Vinorelbine
D000972:Antineoplastic Agents, Phytogenic; D014748:Vinca Alkaloids; D014750:Vincristine; D014747:Vinblastine; D000077235:Vinorelbine; D014751:Vindesine; C017836:catharanthine
Pharmacologie des Catharanthus alcaloïdes.