title: [Complications in multiple systems resulting from acute cerebrovascular diseases].
abstract: One hundred and eighty five patients died of acute cerebrovascular diseases with complications in multiple systems were studied. Statistical analyses showed that there were no organ and system failure (NOSF) in 47 cases, single organ and system failure (SOSF) in 47 and multiple organ and system failure (MOSF) in 91. Out of 90 (50%) cases who had cerebral herniation, 39 cases were complicated with SOSF and 53 cases with MOSF. Among the patients with acute brain diseases, 25% of them (46) died of SOSF (4%, 8 cases) and MOSF (21%, 38) without herniation. Incidence of failure of organ and system was higher with stomach, metabolism and lung than with heart, kidney and blood. It took on the average 24 and 12.5 hours for the first organ and system to fail and 4 days and 24 hours for the second organ in patients with intracranial hemorrhage and cerebral infarction. Occurrence of organ and system failure was closely related to sex, previous diseases and damage of brain stem, but not to the size and number of the lesion. It is suggested that cerebrogenic organ and system failure (COSF) or cerebrogenic multiple organ and system failure (CMOSF) be referred to functional failure of more than two organs or system not including brain itself as a result of acute brain diseases.
authors.affiliation: PLA General Hospital, Beijing.
authors.forename: C
authors.initials: C
authors.lastname: Pu
authors.forename: K
authors.initials: K
authors.lastname: Zhu
authors.forename: G
authors.initials: G
authors.lastname: Wang
mesh_terms: D001933:Brain Stem / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000150:complications*; D004677:Encephalocele / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology*; D012737:Sex Factors