Silent ischemic cardiomyopathy and left coronary ostial stenosis secondary to radiation therapy.
A 55-year-old woman presented with profound congestive heart failure 23 years following mediastinal radiation. Ejection fraction (EF) was 35%. Symptoms markedly improved and EF increased to > 55% following saphenous vein bypass for > or = 80% ostial left main stenosis. Radiation therapy, a known risk factor for coronary atherosclerosis, may present with reversible severe silent ischemia.
Aronow
H
H
Department of Internal Medicine, University of Michigan, Ann Arbor, USA.
Kim
M
M
Rubenfire
M
M
D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000209:etiology*; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008479:Mediastinal Neoplasms / Q000532:radiotherapy; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation; D013318:Stroke Volume / Q000528:radiation effects