Comparison of occurrence of genetic syndromes in ventricular septal defect with pulmonic stenosis (classic tetralogy of Fallot) versus ventricular septal defect with pulmonic atresia.
Our results confirm that classic TF can be associated with many genetic conditions, but most patients are nonsyndromic. In contrast, children with TF-PA have a high incidence of genetic syndromes, particularly those related to CATCH22 syndrome.
Digilio
M C
MC
Department of Pediatric Cardiology, Bambino Gesu Hospital, Rome, Italy.
Marino
B
B
Grazioli
S
S
Agostino
D
D
Giannotti
A
A
Dallapiccola
B
B
D000015:Abnormalities, Multiple / Q000453:epidemiology / Q000235:genetics*; D016022:Case-Control Studies; D002675:Child, Preschool; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000235:genetics*; D006801:Humans; D015994:Incidence; D008297:Male; D015995:Prevalence; D018633:Pulmonary Atresia / Q000235:genetics*; D013577:Syndrome; D013771:Tetralogy of Fallot / Q000235:genetics*