[Structural and biochemical parameters of blood components of mice after gamma irradiation with small doses of different intensity].
The complex study on the low gamma-irradiation on the structural feature of lymphocyte DNA and lipid peroxidation (LPO) regulatory system parameters in mice blood was carried out depending on irradiation intensity. It was found that DNA alkaline elution rate constants, viscosity of the different regions of erythrocyte membranes and LPO products content in mice blood plasma varied nonlinearly depending on dose or dose rate. The proportion of the damage types and the range of the DNA structural changes substantially differ depending on the gamma-irradiation dose and its intensity. It is considered that the proportion of the DNA and membrane damage and repair can change depending on radiation dose and dose rate.
Smotriaeva
M A
MA
Krugliakova
K E
KE
Shishkina
L N
LN
Bliukhterova
N V
NV
Goloshchapov
A N
AN
Burlakova
E B
EB
D000818:Animals; D001773:Blood Cells / Q000378:metabolism / Q000528:radiation effects*; D004247:DNA / Q000528:radiation effects*; D004249:DNA Damage; D004910:Erythrocyte Membrane / Q000378:metabolism / Q000528:radiation effects; D004912:Erythrocytes / Q000378:metabolism / Q000528:radiation effects; D005720:Gamma Rays; D015227:Lipid Peroxidation / Q000528:radiation effects*; D008214:Lymphocytes / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011829:Radiation Dosage
D004247:DNA
Strukturnye i biokhimicheskie pokazateli élementov krovi mysheĭ posle gamma-oblucheniia v malykh dozakh raznoĭ intensivnosti.