title: Hepatocellular carcinoma: iodized-oil CT TNM classification.
abstract: OBJECTIVE
  We conducted a prospective study to determine the efficacy of iodized-oil enhancement in CT for preoperative assessment of the T factor of the TNM classification in patients with hepatocellular carcinoma (HCC).
  
  
  METHODS
  Iodized-oil CT was performed as a part of preoperative staging in 28 patients with HCC. We determined the radiologic T factor. Pathologic correlation was obtained after orthotopic liver transplantation (n = 25) or autopsy (n = 3), and the histologic T factor was determined.
  
  
  RESULTS
  The sensitivity of iodized-oil CT accurately distinguishing between stage-T4 tumors and tumors in stages T1-T3 was 88% (7/8) with a positive predictive value of 100% (7/7).
  
  
  CONCLUSIONS
  Iodized-oil CT is useful for preoperatively assessing the T factor of the TNM classification in HCC, and it improves the accuracy of radiologic staging. Iodized-oil CT can help to better patients with HCC for orthotopic liver transplantation.
authors.affiliation: Department of Radiology, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Valls
authors.forename: J
authors.initials: J
authors.lastname: Figueras
authors.forename: E
authors.initials: E
authors.lastname: Jaurrieta
authors.forename: C
authors.initials: C
authors.lastname: Sancho
authors.forename: J
authors.initials: J
authors.lastname: Dominguez
authors.forename: C
authors.initials: C
authors.lastname: Benasco
authors.forename: P
authors.initials: P
authors.lastname: Moreno
authors.forename: A
authors.initials: A
authors.lastname: Rafecas
authors.forename: J
authors.initials: J
authors.lastname: Virgili
authors.forename: X
authors.initials: X
authors.lastname: Castellsagué
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D003287:Contrast Media; D005260:Female; D006801:Humans; D007459:Iodized Oil; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D007459:Iodized Oil