title: [Experimental studies evaluating oncogenic effects of copper-nickel sulfide ore dust].
abstract: The experiments on animals studied mutagenic activity of copper-nickel sulfide ore dust. Micronucleus test proved mild mutagenic activity of the ore under study. Chronic inhalation of the dust induced malignancies (mostly lung tumors and leukoses) in 52% of the experimental Wistar rats, that could be caused by dissolution of the dust components in the body fluids.
authors.forename: R V
authors.initials: RV
authors.lastname: Borisenkova
authors.forename: L N
authors.initials: LN
authors.lastname: Pylev
authors.forename: L A
authors.initials: LA
authors.lastname: Lutsenko
authors.forename: G Ia
authors.initials: GIa
authors.lastname: Lipatov
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Beresneva
authors.forename: L L
authors.initials: LL
authors.lastname: Gvozdeva
mesh_terms: D000818:Animals; D003300:Copper / Q000633:toxicity*; D003627:Data Interpretation, Statistical; D004391:Dust / Q000009:adverse effects; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D009532:Nickel / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004391:Dust; D003300:Copper; D009532:Nickel; C017558:nickel sulfide
vernacular_title: Eksperimental'nye issledovaniia po otsenke onkogennogo deĭstviia pyli medno-nikelevoĭ sul'fidnoĭ rudy.