title: Hypopituitarism associated with transient diabetes insipidus followed by an episode of painless thyroiditis in a young man.
abstract: A 16-year-old male complained of a headache and a high fever followed by polyuria. The endocrinological studies showed he had hypopituitarism and central diabetes insipidus, and magnetic resonance imaging (MRI) revealed a pituitary mass. Diabetes insipidus gradually improved and hydrocortisone treatment was begun at three months after onset, but a month later painless thyroiditis developed. An MRI demonstrated a spontaneous shrinkage of the pituitary mass nine months after onset. Lymphocytic hypophysitis followed by painless thyroiditis was the most probable diagnosis, although it is very uncommon especially among men.
authors.affiliation: Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka.
authors.forename: T
authors.initials: T
authors.lastname: Mizokami
authors.forename: K
authors.initials: K
authors.lastname: Inokuchi
authors.forename: K
authors.initials: K
authors.lastname: Okamura
authors.forename: R
authors.initials: R
authors.lastname: Yoshimura
authors.forename: K
authors.initials: K
authors.lastname: Hasuo
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Kuroda
authors.forename: M
authors.initials: M
authors.lastname: Fujishima
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003287:Contrast Media; D003919:Diabetes Insipidus / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003937:Diagnosis, Differential; D019786:Gadolinium DTPA; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007018:Hypopituitarism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D007249:Inflammation / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D008218:Lymphocytosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D010900:Pituitary Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013966:Thyroiditis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA; D006854:Hydrocortisone