[A new sorbent for hemosorption].
SIAL, a new granulated white adsorbent, has been obtained. It is characterized by highly porous surface with hydrophilic-hydrophobic properties due to combined effects of the mineral matrix (aluminum oxide) and the coating (organosiloxane fluid) permitted for medical use. The detoxication properties of the adsorbent have been demonstrated in experimental hemosorption. It was shown to exert a moderate effect on the contact phase of blood clotting and on platelet aggregation characteristics.
Kizner
T A
TA
Rachkovskaia
L N
LN
Momot
A P
AP
Mazyrko
A V
AV
Smagin
A A
AA
Burylin
S Iu
SIu
D000537:Aluminum Oxide / Q000494:pharmacology / Q000627:therapeutic use*; D001782:Blood Donors; D001792:Blood Platelets / Q000187:drug effects; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D006464:Hemoperfusion / Q000379:methods*; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D016062:Porosity; D012833:Siloxanes / Q000494:pharmacology / Q000627:therapeutic use*
D004338:Drug Combinations; C100341:SIAL sorbent; D012833:Siloxanes; D000537:Aluminum Oxide
Novyĭ sorbent dlia gemosorbtsii.