title: The management of renal candidiasis in the newborn.
abstract: Renal candidiasis in the neonate is encountered infrequently. We report a newborn with ichthyosis, who during the hospital course had five episodes of culture-proven sepsis, probably due to skin lesions. For these infections various antibiotic combinations were used. During the therapy of the last sepsis attack, unilateral hydronephrosis developed secondary to renal candidiasis. Percutaneous nephrostomy with amphotericin B irrigation, coupled with five weeks of intravenous amphotericin B therapy was successful. We believe that with this approach the mortality and morbidity of renal candidiasis could be reduced.
authors.affiliation: Department of Pediatrics, Istanbul University Faculty of Medicine, Capa-Istanbul.
authors.forename: R
authors.initials: R
authors.lastname: Uçsel
authors.forename: A
authors.initials: A
authors.lastname: Coban
authors.forename: F
authors.initials: F
authors.lastname: Metin
authors.forename: G
authors.initials: G
authors.lastname: Yücer
authors.forename: O
authors.initials: O
authors.lastname: Ziylan
authors.forename: E
authors.initials: E
authors.lastname: Tonguç
authors.forename: I
authors.initials: I
authors.lastname: Bilge
authors.forename: K
authors.initials: K
authors.lastname: Rouzbeksalah
authors.forename: G
authors.initials: G
authors.lastname: Can
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D002177:Candidiasis / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D008297:Male; D009403:Nephrostomy, Percutaneous; D014463:Ultrasonography
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B