[Genotype of hepatitis C virus in hemophiliacs].
Testing of blood sera of 63 hemophiliacs revealed markers of hepatitides B and C in 97 and 98% cases, respectively. Polymerase chain reaction confirmed the presence of hepatitis C virus (HCV) RNA in 31 (94%) out of 33 sera tested which contained antibodies to HCV. Gene typing of the isolated strains revealed the presence of three types of HCV: 1b (94%), 2a (3%), and 3a (3%). Similar distribution of HCV genotypes was revealed in the blood sera of 39 patients with chronic hepatitis C.
Kuzin
S N
SN
Mazhul'
L A
LA
Snegireva
I B
IB
Pliushts
O P
OP
Gorbarets
I P
IP
Shakhgil'dian
I V
IV
Viazov
S O
SO
D002908:Chronic Disease; D005838:Genotype; D006467:Hemophilia A / Q000150:complications*; D016174:Hepacivirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006526:Hepatitis C / Q000150:complications*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000097:blood
D018937:Hepatitis C Antibodies; D012367:RNA, Viral
Genotipy virusa gepatita C u bol'nykh gemofilieĭ.