Protamine reaction in a patient undergoing coronary artery bypass grafting.
The neutralization of heparin anticoagulation is accomplished by the administration of protamine. While the administration of protamine is generally uneventful, allergic reactions can occur. This article describes such a reaction in a patient having cardiac surgery. Classification of protamine reactions and signs and symptoms are discussed. Treatment and management of high risk patients is highlighted.
Hughes
C
C
Haddock
M
M
D000368:Aged; D001026:Coronary Artery Bypass; D004342:Drug Hypersensitivity / Q000145:classification / Q000209:etiology* / Q000628:therapy; D005260:Female; D006494:Heparin Antagonists / Q000009:adverse effects*; D006801:Humans; D011479:Protamines / Q000009:adverse effects*
D006494:Heparin Antagonists; D011479:Protamines