[Change in lipid composition and lipid peroxidation rate in brain tissue under conditions of thymic hormone deficiency].
Experiments on mature male rats have shown that 3 and 6 months after removal of the brain thymus, the level of total lipids in all cell centrifugate fractions (homogenate, supramitochondrial and mitochondrial fractions), which was followed by the higher rate of lipid peroxidation and the lower activity of cellular compartments, the spectrum imbalance of lipid fractions with predominant increases in the levels of phospholipids and free cholesterol. It is suggested that these changes make a contribution to the dysfunction of brain structures and participate in regulatory processes in thymectomy.
Serebrov
V Iu
VIu
Timin
O A
OA
D000818:Animals; D001921:Brain / Q000378:metabolism*; D005260:Female; D050356:Lipid Metabolism; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D051381:Rats; D013951:Thymus Hormones / Q000172:deficiency*
D013951:Thymus Hormones
Izmenenie sostava i skorosti perekisnogo okisleniia lipidov tkani golovnogo mozga v usloviiakh defitsita timusnykh gormonov.