Current status and controversies in the inhalation protocols for the Xenon CT CBF method.
The historical background and current status of the inhalation protocols for the xenon CT CBF method are reviewed. A wash-in method has been established and widely accepted as a standard protocol. A wash-in/washout method is a useful alternative for a practical CBF study. The effect of flow activation with xenon gas can be minimized by shortening the inhalation time. Xe CT CBF method remains to be an indispensable technology for the clinical decision-making in various brain disorders.
Kashiwagi
S
S
Department of Neurosurgery, Yamaguchi University School of Medicine, Japan.
Nagamitsu
T
T
Yamashita
T
T
D001783:Blood Flow Velocity / Q000187:drug effects / Q000502:physiology; D001921:Brain / Q000098:blood supply*; D003287:Contrast Media; D006801:Humans; D015588:Observer Variation; D012016:Reference Values; D012039:Regional Blood Flow / Q000502:physiology; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*; D014978:Xenon; D014980:Xenon Radioisotopes
D003287:Contrast Media; D014980:Xenon Radioisotopes; D014978:Xenon