title: Expression of V-SRC and chromosome analysis of a newly established cell line from rat sarcoma induced by an avian retroviral strain.
abstract: In the newly established rat sarcoma cell line LSR-SF (SR) expression of pp60v-src was detected. Karyotype analyses revealed various chromosome aberrations during prolonged passaging of the tumor cells in vitro. Polyploidy was found to be a characteristic feature of the line studied. A large metacentric chromosome persistently present in the cells was accepted as a line marker.
authors.affiliation: National Center of Infectious and Parasitic Diseases, Central AIDS Laboratory, Bulgarian Academy of Sciences, Sofia, Bulgaria.
authors.forename: M T
authors.initials: MT
authors.lastname: Polianova
authors.forename: P K
authors.initials: PK
authors.lastname: Jordanova
mesh_terms: D000818:Animals; D001358:Avian Sarcoma Viruses; D002869:Chromosome Aberrations; D007621:Karyotyping; D015688:Oncogene Protein pp60(v-src) / Q000032:analysis*; D051381:Rats; D012513:Sarcoma, Experimental / Q000235:genetics*; D014407:Tumor Cells, Cultured
chemical_list: D015688:Oncogene Protein pp60(v-src)