title: Antibacterial and antifungal polyine compounds from Glehnia littoralis ssp. leiocarpa.
abstract: Glehnia littoralis F. Schmidt ssp. leiocarpa (Mathias) Hult. (Apiaceae), a species of ethnopharmacological interest in British Columbia, has antibacterial and antifungal properties. Antibacterial and antifungal compounds include two hitherto unreported polyine compounds, (9Z)1,9-heptadecadiene-4,6-diyne-3,8,11-triol and (10E)1,10-heptadecadiene-4,6-diyne-3,8,9-triol.
authors.affiliation: Department of Botany, University of British Columbia, Vancouver, Canada.
authors.forename: H
authors.initials: H
authors.lastname: Matsuura
authors.forename: G
authors.initials: G
authors.lastname: Saxena
authors.forename: S W
authors.initials: SW
authors.lastname: Farmer
authors.forename: R E
authors.initials: RE
authors.lastname: Hancock
authors.forename: G H
authors.initials: GH
authors.lastname: Towers
mesh_terms: D000480:Alkynes; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D053280:Diynes; D005233:Fatty Alcohols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts; D018517:Plant Roots; D010946:Plants, Medicinal
chemical_list: C100576:1,10-heptadecadiene-4,6-diyne-3,8,9-triol; C100575:1,9-heptadecadiene-4,6-diyne-3,8,11-triol; D000480:Alkynes; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D053280:Diynes; D005233:Fatty Alcohols; D010936:Plant Extracts