title: Allogeneic cartilage used for skull base plasty in children with primary intranasal encephalomeningocele associated with cerebrospinal fluid rhinorrhea.
abstract: Three children with primary intranasal encephalomeningocele associated with cerebrospinal fluid rhinorrhea were operated on at the Department of Neurosurgery, Hradec Králové. In two children, aged 4 and 9.5 years, freeze-dried allogeneic costal cartilage was glued into the skull base defect. This plugging was covered up with deep frozen allogeneic fascia lata. In the third child, an only 1-year-old boy, after transection of the neck of the encephalomeningocele freeze-dried allogeneic dura mater was glued on extradurally and deep-frozen allogeneic fascia lata applied intradurally. The cerebrospinal fluid rhinorrhea ceased immediately after surgery. Spontaneous atrophy of the intranasal portion of the encephalomeningocele was demonstrated respectively 11, 1, and 7 years postoperatively on computed tomography. To evaluate cartilage healing histologically, the extracted allogeneic cartilage used for orbital roof plasty after 4 months was examined. The extent of spotty regressions represented about 7% of the tissue volume. It is stressed that, once diagnosed, intranasal encephalomeningocele associated with cerebrospinal fluid rhinorrhea should be operated on for prevention of meningitis as soon as possible.
authors.affiliation: Department of Neurosurgery, Medical Faculty, Charles University, Hradec Králové, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Parízek
authors.forename: P
authors.initials: P
authors.lastname: Mĕrićka
authors.forename: S
authors.initials: S
authors.lastname: Nĕmecek
authors.forename: J
authors.initials: J
authors.lastname: Nĕmecková
authors.forename: M
authors.initials: M
authors.lastname: Zemánková
authors.forename: M
authors.initials: M
authors.lastname: Sercl
authors.forename: M
authors.initials: M
authors.lastname: Häringová
mesh_terms: D001921:Brain / Q000503:physiopathology* / Q000601:surgery; D001927:Brain Diseases / Q000150:complications* / Q000503:physiopathology* / Q000601:surgery; D002356:Cartilage / Q000601:surgery*; D002559:Cerebrospinal Fluid Rhinorrhea / Q000150:complications* / Q000175:diagnosis; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000503:physiopathology; D009300:Nasal Septum / Q000002:abnormalities / Q000601:surgery; D011183:Postoperative Complications; D012886:Skull / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D014184:Transplantation, Homologous