title: Liver. II: Iron oxide-based reticuloendothelial contrast agents for MR imaging. Clinical review.
abstract: Iron oxide-based compounds are a new class of MR contrast agents that have a wide range of clinical applications.  The biodistribution and subsequent influence on the MR image depends on the particle size.  Iron oxides can be used to increase contrast-to-noise ratio, facilitating the visibility of focal liver lesions.  Other applications include blood-pool imaging and targeting the reticuloendothelial system and cell surface receptors.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston, USA.
authors.forename: J
authors.initials: J
authors.lastname: Petersein
authors.forename: S
authors.initials: S
authors.lastname: Saini
authors.forename: R
authors.initials: R
authors.lastname: Weissleder
mesh_terms: D003287:Contrast Media; D003911:Dextrans; D052203:Ferrosoferric Oxide; D006801:Humans; D007501:Iron; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000175:diagnosis*; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles; D010087:Oxides; D013535:Suspensions
chemical_list: D003287:Contrast Media; D003911:Dextrans; D058185:Magnetite Nanoparticles; D010087:Oxides; D013535:Suspensions; C097921:ferumoxtran-10; D007501:Iron; C065507:ferumoxides; D052203:Ferrosoferric Oxide