Neuronal localization of serotonin in the nematode Ascaris suum.
We have used immunocytochemical techniques to investigate the distribution of serotonin-like immunoreactivity in the nematode Ascaris suum. Antisera raised against serotonin (5-hydroxytryptamine, 5-HT) conjugated to bovine serum albumin (BSA) labelled a pair of neurons in the pharynx of both sexes and five cells in the ventral cord of the male tail. The labelling was blocked by 5-HT or by 5-HT conjugated to BSA. The 5-HT-immunoreactive cells in the pharynx resemble neurosecretory cells and are probably homologous to the neurosecretory motor neurons (NSM) in Caenorhabditis elegans; the cells in the male tail appear to be motor neurons that are homologous to CP neurons in C. elegans. Other cells that stain with 5-HT antisera have been observed in C. elegans but are not seen in Ascaris.
Johnson
C D
CD
Department of Zoology, University of Wisconsin-Madison 53706, USA.
Reinitz
C A
CA
Sithigorngul
P
P
Stretton
A O
AO
D000818:Animals; D017165:Ascaris suum / Q000737:chemistry* / Q000166:cytology; D017173:Caenorhabditis elegans / Q000737:chemistry* / Q000166:cytology; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000737:chemistry*; D010614:Pharynx / Q000737:chemistry* / Q000166:cytology; D012701:Serotonin / Q000032:analysis*
D012701:Serotonin