[Evaluation of blood absorption, hemostatic ability and purity of a polyepoxy compound cross-linked cotton type collagen hemostat].
A polyepoxy compound cross-linked cotton type collagen hemostat (CCH) made of highly purified atelocollagen in a fine filament shape was developed. To evaluate blood absorption, hemostatic ability and purity of the CCH, Avitene and Oxycel were used for comparison. Blood absorption speed of the CCH was faster than Avitene and Oxycel. The handling characteristics of the CCH were much better than those of Avitene and Oxycel. Hemostatic ability was better in the CCH compared to Avitene in a canine study. The purity of the CCH was better than in Avitene which contained albumin and other proteins. Those results suggest that the developed hemostat with excellent blood absorption, handling characteristics, hemostatic ability and purity, could be useful in clinicals.
Tomizawa
Y
Y
Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College, Japan.
Noishiki
Y
Y
Endo
M
M
Hashimoto
A
A
Koyanagi
H
H
D000042:Absorption; D000818:Animals; D002483:Cellulose, Oxidized; D003094:Collagen / Q000592:standards*; D004285:Dogs; D004852:Epoxy Compounds; D005069:Evaluation Studies as Topic; D006490:Hemostatics; D011126:Polypropylenes
D002483:Cellulose, Oxidized; D004852:Epoxy Compounds; D006490:Hemostatics; D011126:Polypropylenes; D003094:Collagen