title: Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.
abstract: The complete 1.66-megabase pair genome sequence of an autotrophic archaeon, Methanococcus jannaschii, and its 58- and 16-kilobase pair extrachromosomal elements have been determined by whole-genome random sequencing. A total of 1738 predicted protein-coding genes were identified; however, only a minority of these (38 percent) could be assigned a putative cellular role with high confidence. Although the majority of genes related to energy production, cell division, and metabolism in M. jannaschii are most similar to those found in Bacteria, most of the genes involved in transcription, translation, and replication in M. jannaschii are more similar to those found in Eukaryotes.
authors.affiliation: Microbiology Department, University of Illinois, Champaign-Urbana, IL 61801, USA.
authors.forename: C J
authors.initials: CJ
authors.lastname: Bult
authors.forename: O
authors.initials: O
authors.lastname: White
authors.forename: G J
authors.initials: GJ
authors.lastname: Olsen
authors.forename: L
authors.initials: L
authors.lastname: Zhou
authors.forename: R D
authors.initials: RD
authors.lastname: Fleischmann
authors.forename: G G
authors.initials: GG
authors.lastname: Sutton
authors.forename: J A
authors.initials: JA
authors.lastname: Blake
authors.forename: L M
authors.initials: LM
authors.lastname: FitzGerald
authors.forename: R A
authors.initials: RA
authors.lastname: Clayton
authors.forename: J D
authors.initials: JD
authors.lastname: Gocayne
authors.forename: A R
authors.initials: AR
authors.lastname: Kerlavage
authors.forename: B A
authors.initials: BA
authors.lastname: Dougherty
authors.forename: J F
authors.initials: JF
authors.lastname: Tomb
authors.forename: M D
authors.initials: MD
authors.lastname: Adams
authors.forename: C I
authors.initials: CI
authors.lastname: Reich
authors.forename: R
authors.initials: R
authors.lastname: Overbeek
authors.forename: E F
authors.initials: EF
authors.lastname: Kirkness
authors.forename: K G
authors.initials: KG
authors.lastname: Weinstock
authors.forename: J M
authors.initials: JM
authors.lastname: Merrick
authors.forename: A
authors.initials: A
authors.lastname: Glodek
authors.forename: J L
authors.initials: JL
authors.lastname: Scott
authors.forename: N S
authors.initials: NS
authors.lastname: Geoghagen
authors.forename: J C
authors.initials: JC
authors.lastname: Venter
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics*; D001482:Base Composition; D001483:Base Sequence; D001692:Biological Transport / Q000235:genetics; D002245:Carbon Dioxide / Q000378:metabolism; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial / Q000235:genetics; D004261:DNA Replication; D004269:DNA, Bacterial / Q000235:genetics*; D016208:Databases, Factual; D004734:Energy Metabolism / Q000235:genetics; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006859:Hydrogen / Q000378:metabolism; D008697:Methane / Q000378:metabolism; D017017:Methanococcus / Q000235:genetics* / Q000502:physiology; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D017422:Sequence Analysis, DNA; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D002245:Carbon Dioxide; D006859:Hydrogen; D008697:Methane