A comparison of the recovery characteristics of sevoflurane and halothane in children.
The recovery characteristics of sevoflurane and halothane anaesthesia were compared in 40 children aged 6 months to 6 years undergoing day case surgery. The mean time taken to open eyes after surgery had ended was appreciably and significantly shorter after sevoflurane than after halothane (sevoflurane, mean time (SD) 7 min 52 s (5 min 46 s), halothane, mean time (SD) 15 min 50 s (9 min 2 s), t = 3.32, p = 0.002). The time taken to be ready for discharge from the recovery unit to the ward was also significantly shorter after sevoflurane than after halothane (sevoflurane, mean time (SD) 12 min 46 s (4 min 11 s), halothane, mean time (SD) 19 min 13 s (9 min 48 s), t = 2.7, p < 0.01). However, more children were in pain and given analgesia after sevoflurane (p < 0.01) and the mean time to reach the criteria for discharge home was similar in both groups (sevoflurane, mean time (SD) 2 h 9 min (17 min), halothane, mean time (SD) 2 h 4 min (8 min)). There were no major complications in either group.
Sury
M R
MR
Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust, London.
Black
A
A
Hemington
L
L
Howard
R
R
Hatch
D J
DJ
Mackersie
A
A
D000556:Ambulatory Surgical Procedures; D000698:Analgesia; D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation / Q000379:methods; D018685:Anesthetics, Inhalation; D002648:Child; D002675:Child, Preschool; D004987:Ethers; D005260:Female; D006221:Halothane; D006801:Humans; D007223:Infant; D008297:Male; D008738:Methyl Ethers; D010149:Postoperative Pain; D000077149:Sevoflurane; D013997:Time Factors
D018685:Anesthetics, Inhalation; D004987:Ethers; D008738:Methyl Ethers; D000077149:Sevoflurane; D006221:Halothane