Serous surface papillary carcinoma of the ovary metastatic to a cervical polyp. A case report.
BACKGROUND
Malignancies in cervical polyps are rare. In the literature, malignant transformation to adenocarcinoma and squamous cell carcinoma has been described, but metastasis from ovarian tumors has not been reported before.


METHODS
An asymptomatic female had a serous surface papillary carcinoma of the ovary, metastatic to a cervical polyp and first noticed on a routine vaginal/cervical/endocervical smear.


CONCLUSIONS
The most common sources of adenocarcinoma cells in a cervical/vaginal smear are the endocervix and endometrium, but, as in our case, the tumor may well be metastatic disease, originating in the ovary or even in extragenital sites, such as gastrointestinal tract, breast and lung. The possibility of dual primaries, involving, for instance, both ovary and endocervix, should be considered.
Jiménez-Ayala
M
M
Department of Pathology, Gregorio Marañón University General Hospital, Madrid, Spain.
Martínez-Cabruja
R
R
Esteban Casado
M L
ML
Chinchilla Redondo
C
C
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D002291:Carcinoma, Papillary / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D002471:Cell Transformation, Neoplastic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D011127:Polyps / Q000473:pathology* / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery