title: [A clinical study of radial prostatectomy].
abstract: BACKGROUND
  The objective of this study is to evaluate the efficacy of radical prostatectomy for patients with organ-confined prostate cancer.
  
  
  METHODS
  From 1990 to 1994, a total of 50 patients with prostate cancer underwent radical retropubic prostatectomy.
  
  
  RESULTS
  Eleven patients were in state A2, 34 in stage B and 5 in stage C according to clinical stage. Extended disease was observed pathologically in 45%, and 59% of patients in clinical stages A2 and B, respectively. Preoperative serum PSA levels were closely correlated with pathological extension of the disease. The disease-free rates for organ-confined disease, extended disease without lymph node metastasis and stage D1 disease were 75% (3 years), 82% (2 years) and 80% (3 years), respectively. Four patients had rectal injuries, and three of these underwent temporary colostomy diversion. Two patients had bladder neck contracture and received internal urethrotomy. Urinary incontinence improved in 60% of patients during the first 6 post-operative and in 90% of patients within 12 post-operative months. Urinary incontinence tended to improve earlier in patients with nerve-sparing than those without it. The erectile capacity in nerve sparing patients recovered good.
  
  
  CONCLUSIONS
  Our results indicate that radical prostatectomy is a safe and temporarily satisfactory treatment for the patient with organ-confined prostate cancer.
authors.affiliation: Department of Urology, Sapporo Medical University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Hotta
authors.forename: N
authors.initials: N
authors.lastname: Miyao
authors.forename: N
authors.initials: N
authors.lastname: Masumori
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
authors.forename: K
authors.initials: K
authors.lastname: Sasamura
authors.forename: H
authors.initials: H
authors.lastname: Kitamura
authors.forename: T
authors.initials: T
authors.lastname: Tsukamoto
authors.forename: K
authors.initials: K
authors.lastname: Takatsuka
authors.forename: H
authors.initials: H
authors.lastname: Adachi
authors.forename: Y
authors.initials: Y
authors.lastname: Takagi
authors.forename: S
authors.initials: S
authors.lastname: Takagi
authors.forename: T
authors.initials: T
authors.lastname: Umehara
authors.forename: M
authors.initials: M
authors.lastname: Kimura
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology / Q000601:surgery*