In vitro inhibition of Helicobacter pylori by extracts of thyme.
Extracts of several plants were tested for inhibitory activity against Helicobacter pylori. Among these plants thyme (aqueous extract) and cinnamon (alcoholic extract) were the most effective. Since aqueous extract of thyme is easier to produce and consume, it was further investigated. Compared with several antibacterials, the thyme extract had a significant inhibitory effect on H. pylori, reducing both its growth and potent urease activity. From the results of this study, the aqueous extract of thyme possesses a therapeutic potential which merits validation by clinical studies.
Tabak
M
M
Food Engineering & Biotechnology Faculty, Technion, Israel.
Armon
R
R
Potasman
I
I
Neeman
I
I
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016480:Helicobacter pylori / Q000187:drug effects* / Q000201:enzymology; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D014510:Urease / Q000187:drug effects / Q000378:metabolism
D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D014510:Urease