Juvenile dermatomyositis.
Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other agents such as intravenous immunoglobulin (IVIG) reduces mortality and morbidity.
Halbert
A R
AR
Department of Dermatology, Princess Margaret Hospital for Children, Subiaco, Western Australia.
D002114:Calcinosis / Q000209:etiology; D002648:Child; D003240:Connective Tissue Diseases / Q000209:etiology; D003286:Contracture / Q000209:etiology; D003882:Dermatomyositis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D018908:Muscle Weakness / Q000503:physiopathology; D009135:Muscular Diseases / Q000209:etiology; D014581:Urticaria / Q000503:physiopathology
D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents