Long-term results of vein grafts interposed in arterial defects using the telescoping anastomotic technique and fibrin glue.
Fibrin glue has been applied in the anastomosis of vein grafts placed in rat femoral arteries using the telescoping technique at both ends of the graft. 34 out of 35 grafts which were patent 1 to 3 weeks post-operatively were kept for 3 months to assess the long-term patency, and the effect of the glue on the diameters of the graft and femoral artery. All 34 grafts were patent 3 months post-operatively. Excessive enlargement of the graft diameter was alleviated by the fibrin glue without affecting the diameter of the femoral artery. The diameter at the proximal anastomosis was 66% and that at the distal anastomosis was 87% of the diameter of the femoral artery.
Saitoh
S
S
Department of Orthopaedics, Shinshu University School of Medicine, Matsumoto City, Japan.
Nakatsuchi
Y
Y
D000714:Anastomosis, Surgical / Q000379:methods*; D000818:Animals; D005263:Femoral Artery / Q000601:surgery*; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005500:Follow-Up Studies; D051381:Rats; D013997:Time Factors; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014654:Vascular Patency; D014680:Veins / Q000637:transplantation*
D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives