Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.
Woo
L W
LW
Department of Medicinal Chemistry, School of Pharmacy and Pharmacology, University of Bath, Bath, UK.
Purohit
A
A
Reed
M J
MJ
Potter
B V
BV
D001665:Binding Sites; D001943:Breast Neoplasms / Q000201:enzymology; D003374:Coumarins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008861:Microsomes / Q000201:enzymology; D010920:Placenta / Q000201:enzymology; D013429:Sulfatases / Q000037:antagonists & inhibitors*; D013449:Sulfonamides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
C100463:4-methylcoumarin 7-O-sulfamate; D003374:Coumarins; D004791:Enzyme Inhibitors; D013449:Sulfonamides; C100462:coumarin 7-O-sulfamate; D013429:Sulfatases; C020121:estrone sulfatase