[An immunological study of the cell wall proteins of Pseudomonas aeruginosa].
A preparation containing P. aeruginosa cell-wall proteins with a mol. wt. of 9-55 kD has been obtained from P. aeruginosa by the method of extraction with the use of tris-EDTA buffer. In experiments on mice this protein preparation has shown pronounced protective properties, but, according to the data of Shwartzman's local reaction, proved to be toxic, perhaps due to the admixture of LPS. The purification of the protein preparation from the admixture of LPS will make it possible to obtain an effective vaccine against P. aeruginosa infection.
Makarenko
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Stanislavskiĭ
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D000818:Animals; D001426:Bacterial Proteins / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification / Q000633:toxicity; D002473:Cell Wall / Q000276:immunology; D007928:Lethal Dose 50; D008070:Lipopolysaccharides / Q000032:analysis; D051379:Mice; D008970:Molecular Weight; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000276:immunology* / Q000472:pathogenicity; D011817:Rabbits; D012703:Serotyping; D012790:Shwartzman Phenomenon / Q000276:immunology; D012882:Skin Tests
D001426:Bacterial Proteins; D008070:Lipopolysaccharides
Immunologicheskoe izuchenie belkov kletochnoĭ stenki Pseudomonas aeruginosa.