[Perioperative fractionated high dose rate brachytherapy in bone and soft-tissue tumors].
The 13 lesions of 11 patients with bone and soft-tissue tumors (four primary and nine recurrent lesions) were treated with surgery and postoperative fractionated high dose rate (HDR) brachytherapy started on the 6-7th day after surgery. The total dose was 40-50 Gy/7-10 fr/6-7d(bid) at 5 mm from the source. Local control was achieved in eight of 13 lesions (62%). Four of the five uncontrolled lesions had macroscopic residual tumor after the surgery. There was one peripheral nerve damage as a side effect. This study indicates that the use of perioperative fractionated HDR brachytherapy is feasible and well tolerated.
Koizumi
M
M
Department of Radiation Oncology, Osaka University Medical School, Japan.
Inoue
T
T
Inoue
T
T
Teshima
T
T
Ohtani
M
M
Tanaka
E
E
Murayama
S
S
Yamazaki
H
H
Nose
T
T
Fukushima
S
S
Uchida
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000532:radiotherapy*; D001918:Brachytherapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D012983:Soft Tissue Neoplasms / Q000532:radiotherapy*