title: [Periodical EEG pattern modifications in herpetic encephalitis treated with acyclovir].
abstract: The presence of PLED or localized or lateralized periodic activity in encephalitis strongly suggests that the encephalitis is due to the herpes simplex virus. Nevertheless, there has been controversy over its clinical significance. In addition, since the introduction of antiviral drugs in the treatment of herpes encephalitis in its initial stages, the prognosis of the disease has improved. We studied nine patients all diagnosed as having herpes encephalitis and treated with acyclovir. The presence or absence of periodic activity and its characteristics were analyzed. It was seen that either there was no such activity, or if there was, it was not exactly as classically described.
authors.affiliation: Servicio de Neurofisiología Clínica, Hospital Universitario La Fe, Valencia.
authors.forename: A
authors.initials: A
authors.lastname: Benetó
authors.forename: E
authors.initials: E
authors.lastname: Gómez
authors.forename: P
authors.initials: P
authors.lastname: Rubio
authors.forename: R
authors.initials: R
authors.lastname: Sobrino
authors.forename: A
authors.initials: A
authors.lastname: Esparza
authors.forename: M
authors.initials: M
authors.lastname: Gil
authors.forename: M
authors.initials: M
authors.lastname: Entrambasaguas
authors.forename: R
authors.initials: R
authors.lastname: Valdivieso
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001921:Brain / Q000503:physiopathology / Q000821:virology; D004569:Electroencephalography; D018792:Encephalitis, Viral / Q000188:drug therapy* / Q000503:physiopathology / Q000821:virology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018139:Simplexvirus / Q000302:isolation & purification*
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir
vernacular_title: Modificaciones del patrón EEG periódico en las encefalitis herpéticas tratadas con aciclovir.