title: Persistence of partial molar placenta and severe preeclampsia after selective termination in a twin pregnancy.
abstract: BACKGROUND
  Triploid molar pregnancies are usually managed by evacuation of the uterine contents.
  
  
  METHODS
  A 25-year-old woman had a clomiphene citrate-induced twin pregnancy. Ultrasound scan at 13 weeks revealed one anomalous twin. Cytogenetic analysis revealed a karyotype of 69, XXY and a normal other twin. In an attempt to salvage the normal fetus, selective termination was successfully performed at 15 weeks by intracardiac potassium chloride injection. However, the placenta continued to grow and severe preeclampsia developed at 19 weeks, requiring pregnancy termination.
  
  
  CONCLUSIONS
  Selective termination of a triploid twin does not guarantee resolution of molar growth and sequelae of the mole; severe preeclampsia can still develop.
authors.affiliation: Department of Obstetrics and Gynecology, University of Michigan, Detroit, USA.
authors.forename: C E
authors.initials: CE
authors.lastname: Nugent
authors.forename: M R
authors.initials: MR
authors.lastname: Punch
authors.forename: M
authors.initials: M
authors.lastname: Barr
authors.forename: L
authors.initials: L
authors.lastname: LeBlanc
authors.forename: M P
authors.initials: MP
authors.lastname: Johnson
authors.forename: M I
authors.initials: MI
authors.lastname: Evans
mesh_terms: D000328:Adult; D000013:Congenital Abnormalities / Q000235:genetics / Q000601:surgery; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications* / Q000473:pathology; D010920:Placenta / Q000473:pathology; D011123:Polyploidy; D011225:Pre-Eclampsia / Q000209:etiology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*; D018607:Pregnancy Reduction, Multifetal; D011272:Pregnancy, Multiple; D014427:Twins; D014594:Uterine Neoplasms / Q000150:complications* / Q000473:pathology