title: Prilocaine 3% is superior to a mixture of bupivacaine and lignocaine for peribulbar anaesthesia.
abstract: We have compared motor block of the extraocular muscles produced by injections of 3% prilocaine and a mixture of equal parts of 2% lignocaine and 0.75% bupivacaine into the medial compartment of the orbit. A volume of 8 ml was used initially, and a vasoconstrictor and hyaluronidase were added to both solutions. Ninety patients undergoing cataract surgery were allocated randomly to one of two groups in double-blind study. Eight minutes after block insertion, the median ocular movement score in the prilocaine group was 1 and in the lignocaine-bupivacaine group 3. This difference was statistically significant (P = 0.016). Twenty of the patients who received prilocaine and 29 of the patients who received the lignocaine-bupivacaine mixture required an additional inferotemporal injection. This difference was not statistically significant (P = 0.094).
authors.affiliation: Department of Anaesthesia, East Surrey Hospital, Surrey.
authors.forename: U R
authors.initials: UR
authors.lastname: Döpfmer
authors.forename: D G
authors.initials: DG
authors.lastname: Maloney
authors.forename: P A
authors.initials: PA
authors.lastname: Gaynor
authors.forename: R M
authors.initials: RM
authors.lastname: Ratcliffe
authors.forename: S
authors.initials: S
authors.lastname: Döpfmer
mesh_terms: D000328:Adult; D000368:Aged; D000765:Anesthesia, Conduction; D000779:Anesthetics, Local; D002045:Bupivacaine; D002387:Cataract Extraction; D004311:Double-Blind Method; D004338:Drug Combinations; D005133:Eye Movements; D005260:Female; D006801:Humans; D008012:Lidocaine; D008297:Male; D008875:Middle Aged; D011318:Prilocaine
chemical_list: D000779:Anesthetics, Local; D004338:Drug Combinations; D011318:Prilocaine; D008012:Lidocaine; D002045:Bupivacaine