[The reaction of mammary tissue basophils to oxytocin].
By means of staining with base brown and toluidin blue mast cells were revealed in paraffine sections of the lactating albino mouse mammalian gland. The character of mast cells distribution in the gland tissue was studied, the distribution density was assessed and the complex morphometric analysis of the mast cells population in normal and 20 min, after administration of oxytocin, stimulating the milk elimination from the alveoli and the following secrete forming in the gland cells was performed. Under initial conditions of the experiment at the inhibition of the secretory process the mast cells degranulation index made 30% while after the administration of oxytocin in increased up to 52%. Correlation between the mast cells groups with the diverse extent of granule content in cytoplasm was changing. Thus, oxytocine effect appears to be the factor, influencing the mast cells population functional activity.
Balakina
G B
GB
Popov
S M
SM
D000818:Animals; D001491:Basophils / Q000187:drug effects* / Q000648:ultrastructure; D005260:Female; D007774:Lactation / Q000187:drug effects; D007958:Leukocyte Count / Q000187:drug effects; D008321:Mammary Glands, Animal / Q000187:drug effects* / Q000648:ultrastructure; D051379:Mice; D008854:Microscopy, Electron; D010120:Oxytocics / Q000494:pharmacology*; D010121:Oxytocin / Q000494:pharmacology*
D010120:Oxytocics; D010121:Oxytocin
Reaktsiia tkanevykh bazofilov molochnoĭ zhelezy na oksitotsin.