title: Efficacy of maduramicin against turkey coccidiosis in battery: a clinical and pathological study.
abstract: Two groups of 24 three-day-old turkeys each were inoculated with Eimeria meleagrimitis sporulated oocytes and fed a diet containing respectively 5 and 6 ppm of maduramicin ammonium. Clinical signs, mortality rates, weight gain, intestinal lesions and replication of the parasite were compared to the data obtained from a group of infected, untreated birds kept in the same experimental conditions over a period of 17 days. The treated birds showed better performances and less severe intestinal damages; the replication and the development of the parasite in the intestinal mucosa were impaired and delayed by the drug. All the data were dose dependent.
authors.affiliation: Dipartimento di Patologia Animale, Università degli Studi di Torino.
authors.forename: S
authors.initials: S
authors.lastname: Cerruti Sola
authors.forename: A
authors.initials: A
authors.lastname: Leoni
authors.forename: A
authors.initials: A
authors.lastname: Agostini
authors.forename: M
authors.initials: M
authors.lastname: Castagnaro
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003048:Coccidiosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D004539:Eimeria; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D007476:Ionophores / Q000627:therapeutic use; D007783:Lactones / Q000627:therapeutic use; D008297:Male; D011201:Poultry Diseases / Q000188:drug therapy* / Q000473:pathology; D014422:Turkeys / Q000469:parasitology*
chemical_list: D000900:Anti-Bacterial Agents; D007476:Ionophores; D007783:Lactones; C018091:maduramicin