[An atypical presentation of a case of Horton's giant-cell arteritis].
Horton giant cell arteritis can present with an atypical clinical picture that often resembles other diseases. In the case described below, the patient initially demonstrated clinical and laboratory evidence of a Candida albicans sepsis, and therefore we started antimycotic treatment with amphotericin B. Because of an adverse reaction to that drug, we added parenteral steroids before every administration of the antimycotic which led to an unexpected improvement of symptoms. This result caused us to reconsider some clinical aspects that could have been interpreted also as vasculitis, in particular for a giant cell arteritis: throbbing temporal headache, diffuse weakness, important rise in ESR, myoarthralgias. We performed a biopsy of the temporal artery that confirmed our diagnosis.
Grignetti
M
M
Istituto di Medicina Clinica, Università degli Studi, Trieste.
Carraro
M
M
Faccini
L
L
D000666:Amphotericin B / Q000008:administration & dosage / Q000009:adverse effects; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects; D001706:Biopsy; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000517:prevention & control; D004359:Drug Therapy, Combination; D013700:Giant Cell Arteritis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D012008:Recurrence; D013699:Temporal Arteries / Q000473:pathology
D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D000666:Amphotericin B; D011241:Prednisone; D006854:Hydrocortisone
L'atipica presentazione di un caso di arterite gigantocellulare di Horton.