title: [Systemic manifestations of adult polycystic kidney disease: an analysis of 205 cases].
abstract: Adult polycystic kidney disease (APKD) is a common genetic disease and one of the important reasons of end stage renal failure. Although renal multiple cysts are clearly an important manifestation of APKD; other systemic manifestations are both common and clinically important. The authors reviewed 205 cases from 180 APKD families (107 male 98 female). Their age ranged from 10 to 71 years. Renal cyst is one of the many renal manifestations. Hypertension, hematuria and flank pain are its major complications. Hepatic cysts, pancreatic cysts, cardiac valvular lesions, intracranial aneurysms and splenic cysts are included in the array of systemic manifestations.
authors.affiliation: Institute of Nephrology, First Hospital, Beijing Medical University.
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Zhong
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003560:Cysts / Q000150:complications; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications; D006801:Humans; D008107:Liver Diseases / Q000150:complications; D008297:Male; D008875:Middle Aged; D010181:Pancreatic Cyst / Q000150:complications; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications* / Q000235:genetics; D011379:Prognosis; D013158:Splenic Diseases / Q000150:complications