title: [Giant fibroadenoma of the breast. Its clinical picture and differential diagnosis. A report of a clinical case].
abstract: An 18-year-old girl came to our Institute with a large tumefaction at the right breast, that during the last year had risen slowly but continuously. She underwent some clinical and instrumental exams that allow us to diagnose a giant adenofibroma or cystosarcoma phyllodes without excluding either of them. Then she undergoes a subcutaneous mastectomy with an application of a prosthesis. From the histologic point of view it is a giant adenofibroma. Giant adenofibroma is a rare breast pathology, always benign. Nowadays we have some difficulties distinguishing it from cystosarcoma phyllodes, which has both a benign and malignant form. It is important to distinguish the two pathologies before operation as they have a different therapeutic approach and a different follow-up. Cystosarcoma phyllodes can in fact relapse and when malignant can cause metastasis.
authors.affiliation: Istituto di Chirurgia Generale e Toracopolmonare, Università degli Studi, Milano.
authors.forename: P
authors.initials: P
authors.lastname: Magnoni
authors.forename: F
authors.initials: F
authors.lastname: Nardi
mesh_terms: D000293:Adolescent; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D015414:Mastectomy, Subcutaneous
vernacular_title: Fibroadenoma gigante della mammella. Inquadramento clinico e diagnosi differenziale. Descrizione di un caso clinico.