title: [Incidence and risk factors of second primary cancers in patients treated for primary pharyngeal cancer].
abstract: About 13% of patients treated for a pharyngeal cancer suffer from a second primary cancer. Excessive consumptions of tobacco and/or alcohol are recognized as risk factors of second primary cancers in these patients. Epidemiologic studies suggest that antioxidant vitamins could have a protective effect on the occurrence of second primary cancers; however, this hypothesis should be confirmed by randomized clinical trials. A better knowledge of the risk factors of second primary cancers in patients with a pharyngeal cancer could help reducing the occurrence of second primary cancers and improving the follow-up of these patients.
authors.affiliation: Hôpital de Chicoutimi, Saint-Vallier, Canada.
authors.forename: F
authors.initials: F
authors.lastname: Brochet
authors.forename: I
authors.initials: I
authors.lastname: Bairati
authors.forename: J
authors.initials: J
authors.lastname: Roy
authors.forename: M
authors.initials: M
authors.lastname: Gélinas
authors.forename: A
authors.initials: A
authors.lastname: Nabid
authors.forename: B
authors.initials: B
authors.lastname: Têtu
authors.forename: B
authors.initials: B
authors.lastname: Mâsse
authors.forename: F
authors.initials: F
authors.lastname: Meyer
mesh_terms: D002170:Canada / Q000453:epidemiology; D006258:Head and Neck Neoplasms / Q000453:epidemiology / Q000556:secondary*; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology / Q000556:secondary*; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D010610:Pharyngeal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D012042:Registries; D012307:Risk Factors; D014801:Vitamin A / Q000097:blood; D014810:Vitamin E / Q000097:blood
chemical_list: D014801:Vitamin A; D014810:Vitamin E
vernacular_title: Incidence et facteurs de risque de seconds cancers primaires chez les patients traités pour un premier cancer du pharynx.