title: [Treatment of herpes simplex keratouveitis with systemic and local administration of acyclovir].
abstract: Sixteen patients with relapsing or chronic HSV keratouveitis were treated during a new attack by acyclovir 15 mg/kg/day by the i.v. route for 5 days with local combination of acyclovir 3% ung. and steroids. In all 16 patients improvement of signs of keratouveitis occurred on the fourth day of therapy, in 10 patients with improvement of visual acuity. In 5 patients perforating keratoplasty was performed on account of turbidity of the cornea. The authors observed four relapses of the disease in the course of 12 months after termination of treatment.
authors.affiliation: I. ocní klinika 1. LF UK, Praha.
authors.forename: E
authors.initials: E
authors.lastname: Ríhová
authors.forename: J
authors.initials: J
authors.lastname: Boguszaková
authors.forename: M
authors.initials: M
authors.lastname: Havlíková
authors.forename: K
authors.initials: K
authors.lastname: Michalová
authors.forename: T
authors.initials: T
authors.lastname: Poch
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage*; D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000008:administration & dosage*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D016849:Keratitis, Herpetic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D014605:Uveitis / Q000188:drug therapy / Q000821:virology
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir
vernacular_title: Lécba herpes simplex keratouveitidy celkovĕ a lokálnĕ podaným acyclovirem.