title: [EDMUS--a new European databank for multiple sclerosis. A brief introduction of ongoing and planned multicenter studies within the scope of the "European Concentrated Action for Multiple Sclerosis"].
abstract: EDMUS, the European Database for Multiple Sclerosis (MS), was established on the occasion of the first European Concerted Action for MS under the auspices of the European Community. The system is user-friendly and makes it possible to record and retrieve data relevant to MS. Within the framework of another European Concerted Action, several international multicenter trials are currently in progress. EVALUED, a validation of the EDMUS system, assesses the interrater variability; PRIMS examines the influence of pregnancy and the post-partum period on the course of MS; and PRESTIMUS investigates predictive factors in suspected MS. Further, planned studies include ERAZMUS (early azathioprine and interferon-beta treatment in MS) and AZASTOP, which is designed to evaluate the effect of stopping azathioprine treatment.
authors.affiliation: Klinische Forschungsgruppe für Multiple Sklerose, Neurologische Klinik und Poliklinik, Julius-Maximilians-Universität, Würzburg.
authors.forename: P
authors.initials: P
authors.lastname: Flachenecker
authors.forename: H P
authors.initials: HP
authors.lastname: Hartung
mesh_terms: D001379:Azathioprine / Q000009:adverse effects / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D016208:Databases, Factual; D004185:Disability Evaluation; D005060:Europe; D005062:European Union; D005260:Female; D006801:Humans; D016899:Interferon-beta / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D015337:Multicenter Studies as Topic; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000503:physiopathology / Q000534:rehabilitation*; D009460:Neurologic Examination / Q000187:drug effects; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology; D011379:Prognosis; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000503:physiopathology
chemical_list: D016899:Interferon-beta; D001379:Azathioprine
vernacular_title: EDMUS--eine europäische Datenbank für multiple Sklerose. Eine kurze Vorstellung bereits laufender und noch geplanter multizentrischer Studien im Rahmen der "Europäischen konzertierten Aktion für multiple Sklerose".