title: Timeliness and use of antibiotic prophylaxis in selected inpatient surgical procedures. The Antibiotic Prophylaxis Study Group.
abstract: BACKGROUND
  Twenty-five percent of all nosocomial infections are wound infections. Professional guidelines support the timely use of preoperative prophylaxis for prevention of postoperative wound infections. Barriers exist in implementing this practice. IPRO, the New York State peer review organization, as part of the Health Care Financing Administration's Health Care Quality Improvement Program, sought to determine the proportion of patients receiving timely antibiotic prophylaxis for aortic grafts, hip replacements and colon resections in 44 hospitals in New York State.
  
  
  METHODS
  IPRO conducted a retrospective medical record review of 44 hospitals through out New York State stratified for teaching, nonteaching status. A sample was drawn of 2651 patients, 2256 from Medicare and 395 from Medicaid, undergoing either abdominal aortic aneurysm repair, partial or total hip replacement or large bowel resection. The study determined the proportion of patients who had documentation of receiving antibiotics and those who received antibiotics timely, that is less than or equal to 2 hours preoperatively.
  
  
  RESULTS
  Eighty-six percent of patients had documentation of receiving an antibiotic. Forty-six percent of aneurysm repairs and 60% of hip replacements had evidence of receiving timely antibiotic prophylaxis, that is within 2 hours prior to surgery. For colon resections, 73% of cases had either oral prophylaxis or timely parenteral therapy. An increased proportion of patients had received parenteral antibiotics prematurely as the surgical start time occurred later in the day. A total of 44 different antibiotics were recorded for prophylaxis.
  
  
  CONCLUSIONS
  Antibiotic prophylaxis was performed in 81% to 94% of cases, however, anywhere from 27% to 54% of all cases did not receive antibiotics in a timely fashion. By delegating implementation of ordered antibiotic prophylaxis to the anesthesia team, timing may be improved and the incidence of postoperative wound infections may decrease.
authors.affiliation: Department of Medical Affairs, IPRO, Lake Success, New York 11042, USA.
authors.forename: A
authors.initials: A
authors.lastname: Silver
authors.forename: A
authors.initials: A
authors.lastname: Eichorn
authors.forename: J
authors.initials: J
authors.lastname: Kral
authors.forename: G
authors.initials: G
authors.lastname: Pickett
authors.forename: P
authors.initials: P
authors.lastname: Barie
authors.forename: V
authors.initials: V
authors.lastname: Pryor
authors.forename: M B
authors.initials: MB
authors.lastname: Dearie
mesh_terms: D019072:Antibiotic Prophylaxis / Q000706:statistics & numerical data*; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery; D017558:Elective Surgical Procedures; D006622:Hip Prosthesis; D006801:Humans; D007420:Intestine, Large / Q000601:surgery; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome