title: Measures of adiposity and coronary heart disease mortality in the Chicago Western Electric Company Study.
abstract: Associations of body mass index (BMI), two measures of percent body fat derived from skinfolds, body weight adjusted for height, triceps and subscapular skinfolds, and their sum, with 22-year coronary heart disease (CHD) mortality were compared in 1707 white men ages 40-55 years at baseline (1958) and free of CHD and cancer in 1961 in the Western Electric Study. Because associations of adiposity measures with CHD mortality differed by length of follow-up, analyses were conducted separately for the first 14 years of follow-up and years 15 through 22. In Cox regression analyses, none of the adiposity measures was significantly related to CHD mortality for the first 14 years of follow-up. For years 15-22, all adiposity measures, except triceps skinfold, were significantly related with adjustment for age, as well as eight other covariates. These results indicate that a positive relation of adiposity to CHD risk may not become apparent until several years after the assessment of adiposity.
authors.affiliation: Department of Preventive Medicine, Northwestern University Medical School, Chicago, Illinois 60611, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Spataro
authors.forename: A R
authors.initials: AR
authors.lastname: Dyer
authors.forename: J
authors.initials: J
authors.lastname: Stamler
authors.forename: R B
authors.initials: RB
authors.lastname: Shekelle
authors.forename: K
authors.initials: K
authors.lastname: Greenlund
authors.forename: D
authors.initials: D
authors.lastname: Garside
mesh_terms: D000273:Adipose Tissue; D000328:Adult; D015992:Body Mass Index; D002641:Chicago / Q000453:epidemiology; D003327:Coronary Disease / Q000150:complications / Q000401:mortality*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D009765:Obesity / Q000150:complications; D016016:Proportional Hazards Models; D012307:Risk Factors; D012885:Skinfold Thickness; D013997:Time Factors