[Current indications for medical treatment of ectopic pregnancy].
Today, the early diagnosis of ectopic pregnancy (EP) is made possible by the assay of plasmatic hCG and the improvement of trans-vaginal sonography. These different tests lead to diagnose the EP before the ruptured stage. Therefore, the medical treatment is today a logical alternative to the surgical one. The medical treatment is mainly based upon the use of methotrexate (MTX). The logical indications for EP medical treatment are: early EP without peritoneum effusion, with hCG < or = 5000 mUI/ml, without embryonic cardiac activity at sonography. The medical therapy by intramuscular injection of MTX at 1 mg/kg gives a success rate of 91.8% similar to the success rate of intra tubal injection of MTX under sonographic control.
Darai
E
E
Service de Gynécologie Obstétrique, CHU Bichat- Claude-Bernard, PARIS.
Sitbon
D
D
Benifla
J L
JL
Sebban
E
E
Renolleau
C
C
Madelenat
P
P
D000465:Algorithms; D006063:Chorionic Gonadotropin / Q000097:blood; D003663:Decision Trees; D005260:Female; D005493:Folic Acid Antagonists / Q000627:therapeutic use*; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D018579:Patient Selection; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal
D006063:Chorionic Gonadotropin; D005493:Folic Acid Antagonists; D008727:Methotrexate
Indications actuelles du traitement médical de la grossesse extra-utérine.