title: Case report: radiation prevention of heterotopic ossification after bone and joint surgery in sites other than hips.
abstract: Five patients were given single dose irradiation in an attempt to prevent heterotopic ossification after bone and joint surgery in sites other than hips. All patients were at risk for the development of post-operative heterotopic ossification. Two patients were treated with 6 Gy and three patients were treated with 7 Gy the day after operation. No complications were encountered. Post-operative heterotopic ossification did not develop in patients who received 7 Gy, whereas treatment failed in the two patients who received 6 Gy. Because this is a case report study, no conclusion could be made. Further investigation is needed to assess the efficacy of post-operative single dose irradiation in heterotopic ossification prophylaxis in sites other than hips in high risk patients.
authors.affiliation: Department of Radiation Oncology, Lahey Hitchcock Medical Center, Burlington, MA 01805, USA.
authors.forename: T C
authors.initials: TC
authors.lastname: Lo
authors.forename: B A
authors.initials: BA
authors.lastname: Pfeifer
authors.forename: P M
authors.initials: PM
authors.lastname: Smiley
authors.forename: G J
authors.initials: GJ
authors.lastname: Gumley
mesh_terms: D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000601:surgery*; D005260:Female; D005542:Forearm / Q000000981:diagnostic imaging; D006801:Humans; D007596:Joints / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000000981:diagnostic imaging / Q000517:prevention & control*; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000517:prevention & control*; D011859:Radiography; D011882:Radiotherapy, High-Energy; D011884:Radius / Q000000981:diagnostic imaging