title: [Current indications for medical treatment of ectopic pregnancy].
abstract: Today, the early diagnosis of ectopic pregnancy (EP) is made possible by the assay of plasmatic hCG and the improvement of trans-vaginal sonography. These different tests lead to diagnose the EP before the ruptured stage. Therefore, the medical treatment is today a logical alternative to the surgical one. The medical treatment is mainly based upon the use of methotrexate (MTX). The logical indications for EP medical treatment are: early EP without peritoneum effusion, with hCG < or = 5000 mUI/ml, without embryonic cardiac activity at sonography. The medical therapy by intramuscular injection of MTX at 1 mg/kg gives a success rate of 91.8% similar to the success rate of intra tubal injection of MTX under sonographic control.
authors.affiliation: Service de Gynécologie Obstétrique, CHU Bichat- Claude-Bernard, PARIS.
authors.forename: E
authors.initials: E
authors.lastname: Darai
authors.forename: D
authors.initials: D
authors.lastname: Sitbon
authors.forename: J L
authors.initials: JL
authors.lastname: Benifla
authors.forename: E
authors.initials: E
authors.lastname: Sebban
authors.forename: C
authors.initials: C
authors.lastname: Renolleau
authors.forename: P
authors.initials: P
authors.lastname: Madelenat
mesh_terms: D000465:Algorithms; D006063:Chorionic Gonadotropin / Q000097:blood; D003663:Decision Trees; D005260:Female; D005493:Folic Acid Antagonists / Q000627:therapeutic use*; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D018579:Patient Selection; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal
chemical_list: D006063:Chorionic Gonadotropin; D005493:Folic Acid Antagonists; D008727:Methotrexate
vernacular_title: Indications actuelles du traitement médical de la grossesse extra-utérine.