[Preparation and characterization of liposomal adriamycin].
We established a more suitable methodology for preparing liposomal adriamycin (Lipo-ADM) by a remote loading technique. This procedure is convenient, simple with an entrapment efficiency of 95%. The mean diameter of liposome is about 100nm showing unilamellar spherical shape. The leakage ratio is about 10% within 24hr. Those characteristics fit for clinical demand.
Feng
B
B
Peking Union Medical College Hospital, Beijing.
Lang
J
J
Li
D
D
D004317:Doxorubicin / Q000008:administration & dosage*; D004337:Drug Carriers; D006863:Hydrogen-Ion Concentration; D008081:Liposomes; D008956:Models, Chemical; D013678:Technology, Pharmaceutical
D004337:Drug Carriers; D008081:Liposomes; D004317:Doxorubicin