Age-related endocrine deficiencies and fractures of the proximal femur. II implications of vitamin D deficiency in the elderly.
In the United Kingdom, as many as 60% of institutionalized people who are not taking vitamin D supplements may be deficient. Both impaired mineralization and a hyperparathyroidism-related increase in bone turnover have been identified in the presence of vitamin D deficiency. Recent interventional data have confirmed the role of vitamin D deficiency in the pathogenesis of senile osteoporosis and indicated the need to maintain serum cholecalciferol levels within the normal range in elderly people.
Boonen
S
S
Department of Internal Medicine, Katholieke Universiteit Leuven, Belgium.
Aerssens
J
J
Dequeker
J
J
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism*; D001862:Bone Resorption / Q000209:etiology; D006620:Hip Fractures / Q000378:metabolism*; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications / Q000209:etiology / Q000378:metabolism; D014801:Vitamin A / Q000008:administration & dosage; D014808:Vitamin D Deficiency / Q000378:metabolism*
D014801:Vitamin A