Chromosome reorganization in Candida albicans 1001 strain.
The karotype of Candida albicans 1001, a pathogenic isolate, presents two additional chromosome bands when compared with C. albicans 1006 strain. These two bands were a 2600 kb chromosome located between chromosome group 1-R and chromosome 2 (named chromosome 2*) and a 710 kb small chromosome, called snc due to its similarity in size to the supernumerary chromosome in strain WO-1. A comparison of karyotypes of strains 1001, 1006 and WO-1 has enabled us to conclude that chromosomes 2 and 7 are involved in such a reorganization giving rise to the new chromosome bands of strain 1001. We describe a tentative physical map of C. albicans 1001 based on the previously outlined map of C. albicans strain 1006.
Navarro-García
F
F
Departamento de Microbiologia II, Facultad de Farmacia, Universidad Complutense, Madrid, Spain.
Pérez-Diaz
R M
RM
Magee
B B
BB
Pla
J
J
Nombela
C
C
Magee
P t
Pt
D002176:Candida albicans / Q000235:genetics*; D002875:Chromosomes / Q000235:genetics*; D015321:Gene Rearrangement; D007621:Karyotyping; D013045:Species Specificity