title: Multiple inflammatory fibrosarcoma of the abdominal cavity in a child.
abstract: Inflammatory fibrosarcoma is a rare condition in childhood. In the abdominal location, its behaviour is often aggressive and potentially metastasizing. We report a case of a 3-year-old female with abdominal inflammatory fibrosarcoma who relapsed after 1 month from radical surgery. Chemotherapy was ineffective, and we registered a brief stabilisation of disease only with alpha-IFN. Our case confirms the potential malignancy of this tumour and its resistance to treatment. It is noteworthy that the therapy with alpha-IFN improved the quality of life in this child for 4 months.
authors.affiliation: Department of Haematology-Oncology, Giannina Gaslini Children's Hospital, Genoa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Conte
authors.forename: C
authors.initials: C
authors.lastname: Milanaccio
authors.forename: M
authors.initials: M
authors.lastname: Nantron
authors.forename: E
authors.initials: E
authors.lastname: Castagnola
authors.forename: G
authors.initials: G
authors.lastname: Fratino
authors.forename: G P
authors.initials: GP
authors.lastname: Cuneo
authors.forename: M
authors.initials: M
authors.lastname: Brisigotti
authors.forename: A
authors.initials: A
authors.lastname: Garaventa
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D009378:Neoplasms, Multiple Primary / Q000473:pathology
chemical_list: D016898:Interferon-alpha