title: [Blood interface in environmental and occupational exposure to industrial chemical pollutants].
abstract: The concentration of 12 environmental chemical pollutants was measured in the blood of the general population. With reference to the 12 different pollutants, the blood samples tested varied from 88 for acetone to 431 for benzene. Nine of these agents (benzene, toluene, styrene, cumene, xilene, n-hexane, nitrous oxide (N20), acetone and carbon disulphide) were present in all or almost all (100-94%) blood samples. The three chlorides (chloroform, trichloroethylene and tetrachloroethylene) were present only in 60-85% of samples. After acetone and carbon disulphide, with blood concentrations in microgram/l (mean 840 micrograms/l and 2.4 micrograms/l respectively), the highest mean blood levels were those of toluene (1097 ng/l), chloroform (955 ng/l), N2O (915 ng/l), and n-hexane (642 ng/l). Trichloroethylene and free carbon disulphide had similar values (458 and 438 ng/l, respectively). Finally, benzene, styrene and tetrachloroethylene had the lowest values (262, 217 and 149 ng/l, respectively). There was generally a significant difference between rural and urban workers in terms of blood benzene (200 ng/l vs. 264 ng/l), trichloroethylene (180 ng/l vs 763 ng/l) and tetrachloroethylene (62 ng/l vs. 263 ng/l). In a group of subjects potentially exposed to industrial solvents, classed as chemical workers, blood benzene, toluene, chloroform and n-hexane were significantly higher than in rural and urban workers. Smokers showed a significantly higher blood concentration than non-smokers for benzene (381 ng/l vs. 205 ng/l), toluene (1431 ng/l vs. 976 ng/l) and n-hexane (803 ng/l vs. 505 ng/l).
authors.affiliation: Cattedra di Medicina del Lavoro, Università degli Studi di Verona.
authors.forename: F
authors.initials: F
authors.lastname: Brugnone
authors.forename: L
authors.initials: L
authors.lastname: Perbellini
mesh_terms: D000096:Acetone / Q000097:blood; D000395:Air Pollutants, Occupational / Q000097:blood*; D001554:Benzene / Q000032:analysis; D001555:Benzene Derivatives / Q000097:blood; D002244:Carbon / Q000097:blood; D017554:Carbon Compounds, Inorganic; D002617:Chemical Industry; D002725:Chloroform / Q000097:blood; D004785:Environmental Pollutants / Q000097:blood*; D006586:Hexanes / Q000097:blood; D006801:Humans; D009609:Nitrous Oxide / Q000097:blood; D012424:Rural Population; D012907:Smoking; D020058:Styrene; D013343:Styrenes / Q000097:blood; D013440:Sulfides / Q000097:blood; D013750:Tetrachloroethylene / Q000097:blood; D014050:Toluene / Q000097:blood; D014241:Trichloroethylene / Q000097:blood; D014505:Urban Population; D014992:Xylenes / Q000097:blood
chemical_list: D000395:Air Pollutants, Occupational; D001555:Benzene Derivatives; D017554:Carbon Compounds, Inorganic; D004785:Environmental Pollutants; D006586:Hexanes; D013343:Styrenes; D013440:Sulfides; D014992:Xylenes; D000096:Acetone; D014241:Trichloroethylene; C092035:carbon sulfide; D014050:Toluene; D020058:Styrene; D002244:Carbon; D002725:Chloroform; C015763:cumene; D001554:Benzene; D009609:Nitrous Oxide; D013750:Tetrachloroethylene
vernacular_title: L'interfaccia ematica nell'esposizione ambientale e professionale a inquinanti chimici industriali.