title: [Preparation and characterization of liposomal adriamycin].
abstract: We established a more suitable methodology for preparing liposomal adriamycin (Lipo-ADM) by a remote loading technique. This procedure is convenient, simple with an entrapment efficiency of 95%. The mean diameter of liposome is about 100nm showing unilamellar spherical shape. The leakage ratio is about 10% within 24hr. Those characteristics fit for clinical demand.
authors.affiliation: Peking Union Medical College Hospital, Beijing.
authors.forename: B
authors.initials: B
authors.lastname: Feng
authors.forename: J
authors.initials: J
authors.lastname: Lang
authors.forename: D
authors.initials: D
authors.lastname: Li
mesh_terms: D004317:Doxorubicin / Q000008:administration & dosage*; D004337:Drug Carriers; D006863:Hydrogen-Ion Concentration; D008081:Liposomes; D008956:Models, Chemical; D013678:Technology, Pharmaceutical
chemical_list: D004337:Drug Carriers; D008081:Liposomes; D004317:Doxorubicin