title: [Thrombolytic therapy in arterial disorders other than myocardial infarction].
abstract: Thrombolytic therapy is used in many cardiovascular diseases other than myocardial infarction and pulmonary embolism. In unstable angina, the results of trials have rather been disappointing. In prosthetic valve thrombosis, the role of thrombolytic therapy is increasing. In peripheral arterial thrombosis, intravenous thrombolysis was practically abandonned and local administration has been tried but no systematic attitude can be deduced. In cerebral arterial thrombosis intravenous alteplase thrombolytic treatment is effective and relatively safe in a well defined subgroup of stroke patients with moderate to severe neurologic deficit and without extended infarct signs on the initial CT scan.
authors.affiliation: Centre de biologie moléculaire et vasculaire, Université de Louvain, Leuven, Belgique.
authors.forename: M
authors.initials: M
authors.lastname: Verstraete
mesh_terms: D000789:Angina, Unstable / Q000188:drug therapy; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D002561:Cerebrovascular Disorders / Q000188:drug therapy; D004333:Drug Administration Routes; D004334:Drug Administration Schedule; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D010960:Plasminogen Activators / Q000008:administration & dosage; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology
chemical_list: D005343:Fibrinolytic Agents; D010960:Plasminogen Activators
vernacular_title: Traitement thrombolytique des troubles artériels autres que l'infarctus du myocarde.