title: Aortic prosthetic infection: 50 patients treated by radical or local surgery.
abstract: Fifty patients with aortic prosthetic infection were managed in a period of 10 years from 1983 to 1993. Twenty-five patients had recurrent sepsis after local surgery (group 1) and 22 of these eventually required radical surgery. Twenty-five patients had radical graft excision as the first procedure (group 2). Group 1 contained an excess of patients with local groin symptoms (11 in group 1 versus five in group 2, P = 0.03) and in this group fewer radiological techniques were used to document the extent of graft infection. The perioperative mortality rate was similar in both groups (seven in group 1 versus five in group 2). The number of amputations was also similar (five in group 1 versus four in group 2). The triad of occlusive disease, aortobifemoral bypass and groin symptoms was associated with eight of nine amputations. While the authors would consider using local techniques if the anastomosis was intact, the graft remained patent and infection appeared to be confined to the groin, this combination is uncommon and radical graft excision remains the preferred treatment.
authors.affiliation: Vascular Surgical Unit, St Mary's Hospital, London, UK.
authors.forename: R J
authors.initials: RJ
authors.lastname: Hannon
authors.forename: J H
authors.initials: JH
authors.lastname: Wolfe
authors.forename: A O
authors.initials: AO
authors.lastname: Mansfield
mesh_terms: D000671:Amputation, Surgical; D001018:Aortic Diseases / Q000209:etiology / Q000601:surgery*; D001424:Bacterial Infections / Q000209:etiology / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D005500:Follow-Up Studies; D017721:Hospital Costs; D006801:Humans; D007412:Intestinal Fistula / Q000209:etiology; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000601:surgery*; D012008:Recurrence; D015996:Survival Rate; D016896:Treatment Outcome