Case report: reversible gastroparesis in patients with hypopituitary disease.
A 72-year-old woman with chronic fatigue, malaise, weight loss, nausea, and vomiting was treated unsuccessfully for gastroparesis for more than 2 years. Clinical and biochemical features of hypopituitary disease and symptoms of a nonsecreting pituitary tumor had been overlooked and became apparent only after the differential diagnosis of hyponatremia was considered. Transsphenoidal resection of the pituitary tumor and appropriate 1-thyroxine and hydrocortisone replacement returned her gastric emptying time to normal and relieved her symptoms. Primary and secondary deficits of l-thyroxine and cortisol should be considered when making a possible diagnosis of gastroparesis.
Krishna
A Y
AY
Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Blevins
L S
LS
D000236:Adenoma / Q000150:complications / Q000601:surgery; D000368:Aged; D005260:Female; D005746:Gastric Emptying; D018589:Gastroparesis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007018:Hypopituitarism / Q000150:complications*; D010911:Pituitary Neoplasms / Q000150:complications / Q000601:surgery; D013974:Thyroxine / Q000627:therapeutic use
D013974:Thyroxine; D006854:Hydrocortisone