[Perioperative antibiotic prophylaxis in breast surgery: cefotiam versus clindamycin].
97 patients undergoing breast surgery received either 2 g cefotiam or 1200 mg clindamycin as i.v. singleshot application in the course of an open randomised comparison of parallel groups to evaluate the efficacy and tolerability of both antibiotic regimens. Both regimens proved to be well to-lerated and equally suitable for the prophylaxis of postoperative infections in breast surgery.
Bier
U W
UW
Abteilung für Gynăkologie insbesondere gynäkologische Onkologie, Zentrum für Frauenheilkunde am Universitätsklinikum Essen.
Hoyme
U B
UB
Conrad
S
S
Walz
K A
KA
Winkler
U H
UH
Kleutgens
K
K
Schindler
A E
AE
D000293:Adolescent; D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis; D015310:Cefotiam / Q000009:adverse effects / Q000627:therapeutic use*; D002981:Clindamycin / Q000009:adverse effects / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D016462:Mammaplasty; D008408:Mastectomy; D008875:Middle Aged; D012086:Reoperation; D012307:Risk Factors; D013530:Surgical Wound Infection
D002981:Clindamycin; D015310:Cefotiam
Perioperative Antibiotikaprophylaxe in der Mammachirurgie: Cefotiam versus Clindamycin.