title: [The pathophysiological mechanisms of disorders of cerebral circulation and the new directions in their prevention and treatment].
abstract: The contribution of Laboratory of Nervous System's Experimental Pathology (Institute of Neurology of Russian Academy of Medical Sciences) to cerebrovascular circulation investigations is described. The following questions were considered: cerebral circulation in cerebrovascular disturbances, collateral circulation in the "turned off" state of different brain arteries, and immunological brain alterations as the result of brain organic diseases. Results of the investigation of the damaging effect of acute increase in arterial pressure as well as individual sensitivity to brain ischemia and to drug administration were presented. The particular importance of researches of blood circulation biomechanics as well as of factors of its normalization were also emphasized.
authors.forename: I V
authors.initials: IV
authors.lastname: Gannushkina
mesh_terms: D000047:Academies and Institutes; D000818:Animals; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control / Q000628:therapy; D006801:Humans; D012106:Research / Q000639:trends; D012426:Russia; D014586:USSR
vernacular_title: Patofiziologicheskie mekhanizmy narusheniĭ mozgovogo krovoobrashcheniia i novye napravleniia v ikh profilaktike i lechenii.