[Results of postoperative cervical node irradiation in carcinoma of the pharyngo-larynx. A study of the cooperative group of radiotherapists].
From 1981 to 1985, 428 patients presenting with an epidermoid carcinoma of the hypopharynx and/or larynx were treated with a curative intent by surgical resection and postoperative irradiation. Two-thirds of the tumours were T3 and 60% of patients presented with a clinical node involvement. The rates of local failure were 8%, 18% and 13%, respectively, for cancers of the larynx, of the piriform sinus and of the posterior wall; the rates of regional failure were 8%, 23% and 13%, respectively. There is no head and neck site with either a high or low risk of recurrence after resection, but the capsular rupture remains a factor of poor prognosis. The survival rate at 5 years of the whole series is 38%, for laryngeal localisation it reaches 62%. The risk of metastases is related to the node involvement and the interval between surgery and irradiation.
Hoffstetter
S
S
Centre Alexis-Vautrin, Vandoeuvre-lès-Nancy, France.
Malissard
L
L
N'Guyen
T D
TD
Panis
X
X
Jung
G M
GM
Bachaud
J M
JM
Prevost
B
B
Quint
R
R
Chaplain
G
G
Eschwège
F
F
Rambert
P
P
Fleury-Touzeau
F
F
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D015182:Lymphatic Irradiation; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009333:Neck; D010610:Pharyngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011184:Postoperative Period; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D016019:Survival Analysis
Résultats de l'irradiation ganglionnaire cervicale postopératoire dans les carcinomes du pharyngolarynx. Etude du groupe coopérateur des radiothérapeutes de centre.