title: Langerhans cell histiocytosis in monocygote twins: case reports.
abstract: Langerhans cell histiocytosis includes three clinical forms of histiocytosis X. We describe a disseminated form of Langerhans cell histiocytosis (Letterer-Siwe disease) in monozygotic twins. The twins showed simultaneous onset of disease, almost identical clinical follow-up and findings on cranial CT. The cause of this phenomenon remains unknown.
authors.affiliation: Department of Diagnostic Radiology, University Hospital, Kantonsspital, Basel, Switzerland.
authors.forename: I
authors.initials: I
authors.lastname: Mader
authors.forename: K W
authors.initials: KW
authors.lastname: Stock
authors.forename: E W
authors.initials: EW
authors.lastname: Radue
authors.forename: W
authors.initials: W
authors.lastname: Steinbrich
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D004200:Diseases in Twins / Q000235:genetics*; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male; D013100:Sphenoid Bone / Q000000981:diagnostic imaging; D013701:Temporal Bone / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014430:Twins, Monozygotic / Q000235:genetics