title: Erythroderma. A clinical and follow-up study of 102 patients, with special emphasis on survival.
abstract: BACKGROUND
  Erythroderma may result from different causes. There have been no publications on this subject with special emphasis on survival.
  
  
  OBJECTIVE
  The aim of the study was to determine the cause of the erythroderma and the prognosis of these patients.
  
  
  METHODS
  Clinical and follow-up data from 102 patients with erythroderma were analyzed. We estimated survival of patients with erythroderma, from causes other than Sézary syndrome, mycosis fungoides, or leukemia cutis. The survival was compared with that of an age-matched control group of the general population.
  
  
  RESULTS
  The main cause of erythroderma was exacerbation of a preexisting dermatosis (53%). Drug reactions were rarely the cause (5%). A high proportion of the patients had chronic actinic dermatitis/actinic reticuloid (12%). Survival of men with erythroderma was significantly lower than that of the general population.
  
  
  CONCLUSIONS
  Men with erythroderma, from causes other than Sézary syndrome, mycosis fungoides, or leukemia cutis, have a lower survival than men in the general population.
authors.affiliation: Department of Dermatology, University Hospital, Utrecht, The Netherlands.
authors.forename: V
authors.initials: V
authors.lastname: Sigurdsson
authors.forename: J
authors.initials: J
authors.lastname: Toonstra
authors.forename: M
authors.initials: M
authors.lastname: Hezemans-Boer
authors.forename: W A
authors.initials: WA
authors.lastname: van Vloten
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003873:Dermatitis, Exfoliative / Q000209:etiology* / Q000473:pathology; D003875:Drug Eruptions / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007938:Leukemia; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides; D009426:Netherlands; D010787:Photosensitivity Disorders / Q000150:complications; D011379:Prognosis; D012737:Sex Factors; D012751:Sezary Syndrome; D012871:Skin Diseases / Q000150:complications; D012878:Skin Neoplasms; D015996:Survival Rate