Ascosteroside, a new antifungal agent from Ascotricha amphitricha. II. Isolation and structure elucidation.
The novel antifungal agent ascosteroside (1) was isolated from cultured broth of Ascotricha amphitricha (ATCC 74237). The structure based on spectroscopic data was determined to be an alpha-linked glycoside of a lanostane-type triterpenoid.
Leet
J E
JE
Bristol-Myers Squibb Company, Pharmaceutical Research Institute, Wallingford, Connecticut 06492, USA.
Huang
S
S
Klohr
S E
SE
McBrien
K D
KD
D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D013098:Xylariales
D000935:Antifungal Agents; D006027:Glycosides; D014315:Triterpenes; C100703:ascosteroside