title: [The phenotypic characteristics of healthy carriers of the antigenic structures of the influenza A virus].
abstract: Highly sensitive methods for the detection of viral antigens with the use of monoclonal or polyclonal enzyme immunoassay test systems, as well as virus-specific nucleic sequences (NS-gene) in polymerase chain reaction, made it possible to establish the fact of long-term asymptomatic virus carriership (AVC) in some of adolescent schoolchildren in a closed group. The occurrence of AVC varied at different phases of the epidemic process. The tendency to AVC was observed in individuals having blood group B (III) and HLA-A9 antigen of the major histocompatibility complex. The development of AVC occurred in the presence of a decreased level of humoral immunity. AVC was mainly registered among individuals, relatively resistant to relapsing clinically pronounced forms of respiratory virus infections.
authors.forename: L M
authors.initials: LM
authors.lastname: Tsybalova
authors.forename: A A
authors.initials: AA
authors.lastname: Sominina
authors.forename: T L
authors.initials: TL
authors.lastname: Popova
authors.forename: I E
authors.initials: IE
authors.lastname: Filippova
authors.forename: E A
authors.initials: EA
authors.lastname: Zibina
authors.forename: T A
authors.initials: TA
authors.lastname: Bekhtereva
authors.forename: I I
authors.initials: II
authors.lastname: Konovalova
authors.forename: E M
authors.initials: EM
authors.lastname: Voĭtsekhovskaia
authors.forename: I B
authors.initials: IB
authors.lastname: Semilutskaia
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D000956:Antigens, Viral / Q000032:analysis*; D002353:Carrier State / Q000276:immunology* / Q000821:virology; D005455:Fluorescent Antibody Technique; D006801:Humans; D007113:Immunity, Innate; D007124:Immunoenzyme Techniques; D009980:Influenza A virus / Q000276:immunology* / Q000302:isolation & purification; D007251:Influenza, Human / Q000235:genetics / Q000276:immunology* / Q000821:virology; D009305:Nasopharynx / Q000821:virology; D010641:Phenotype; D016133:Polymerase Chain Reaction
chemical_list: D000956:Antigens, Viral
vernacular_title: Fenotipicheskie osobennosti zdorovykh nositeleĭ antigennykh struktur virusa grippa A.