title: [Pharmacology of Catharanthus alkaloids].
abstract: Catharanthus alkaloids are antitumoral drugs widely used in the treatment of malignant diseases. This review summarizes different aspects of their pharmacology (mechanism of action, resistance, clinical pharmacokinetics) as well as information on their uses in the clinical setting.
authors.affiliation: Laboratoire de pharmacocinétique, Institut de Bactériologie, Strasbourg, France.
authors.forename: D
authors.initials: D
authors.lastname: Levêque
authors.forename: J
authors.initials: J
authors.lastname: Wihlm
authors.forename: F
authors.initials: F
authors.lastname: Jehl
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology*; D004347:Drug Interactions; D004361:Drug Tolerance; D006801:Humans; D014747:Vinblastine / Q000031:analogs & derivatives / Q000494:pharmacology; D014748:Vinca Alkaloids / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology*; D014750:Vincristine / Q000494:pharmacology; D014751:Vindesine / Q000494:pharmacology; D000077235:Vinorelbine
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014748:Vinca Alkaloids; D014750:Vincristine; D014747:Vinblastine; D000077235:Vinorelbine; D014751:Vindesine; C017836:catharanthine
vernacular_title: Pharmacologie des Catharanthus alcaloïdes.