title: Propranolol reduces the anxiety associated with day case surgery.
abstract: OBJECTIVE
  To find out if propranolol, a non-cardioselective beta-blocker, can reduce the anxiety associated with day case surgery.
  
  
  METHODS
  Prospective randomized double blind trial.
  
  
  METHODS
  University hospital, Ireland.
  
  
  METHODS
  An unselected group of 53 patients undergoing day case surgery.
  
  
  METHODS
  Subjects randomised to receive either propranolol (10 mg) or placebo on the morning of operation.
  
  
  METHODS
  Blood pressure; pulse, anxiety, pain score and patient satisfaction.
  
  
  RESULTS
  Mean (SD) Hospital Anxiety and Depression score was significantly lower in the propranolol group than in the control group (2.5 (0.7) compared with 4.6 (0.7), p < 0.0001) before discharge.
  
  
  CONCLUSIONS
  A low dose of propranolol given on the morning of day case surgery significantly reduced patients' anxiety.
authors.affiliation: Dept. of Surgery, Adelaide Hospital, Dublin, Ireland.
authors.forename: K
authors.initials: K
authors.lastname: Mealy
authors.forename: N
authors.initials: N
authors.lastname: Ngeh
authors.forename: P
authors.initials: P
authors.lastname: Gillen
authors.forename: G
authors.initials: G
authors.lastname: Fitzpatrick
authors.forename: F B
authors.initials: FB
authors.lastname: Keane
authors.forename: A
authors.initials: A
authors.lastname: Tanner
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D000328:Adult; D000556:Ambulatory Surgical Procedures; D014151:Anti-Anxiety Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D011433:Propranolol / Q000494:pharmacology / Q000627:therapeutic use*; D011446:Prospective Studies
chemical_list: D000319:Adrenergic beta-Antagonists; D014151:Anti-Anxiety Agents; D011433:Propranolol