[Effect of resection of the proximal part of the small intestine on inhibition of gastric secretion as affected by pituitrin, gastrozepin and histodil].
Semichronic experiments on rats with gastric fistula have revealed that the resection of the proximal third of the small intestine results in impairments of the gastric secretion inhibition induced by gastrozepin or histodil blockade of M-choline- and H2-receptors. At the same time the operation has no noticeable impact on the gastric secretion inhibition caused by pituitrin (vasopressin) on V1-receptors. The difference found is accounted for by a relative specialization of the enterogastric influences that regulate the sensitivity of gastric secretory mechanisms to inhibitory signals.
Trefilov
A B
AB
D000818:Animals; D018680:Cholinergic Antagonists; D002927:Cimetidine / Q000494:pharmacology*; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D006635:Histamine H2 Antagonists / Q000494:pharmacology*; D007421:Intestine, Small / Q000601:surgery; D010890:Pirenzepine / Q000494:pharmacology*; D010909:Pituitary Hormones, Posterior / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D018680:Cholinergic Antagonists; D006635:Histamine H2 Antagonists; D010909:Pituitary Hormones, Posterior; D010890:Pirenzepine; D002927:Cimetidine
Vliianie rezektsii proksimal'noĭ chasti tonkoĭ kishki na tormozhenie zheludochnoĭ sekretsii, vyzyvaemoe pituitrinom, gastrotsepinom i gistodilom.