title: The sign of Leser-Trelat associated with esophageal carcinoma.
abstract: A 79-year-old woman was admitted to our hospital with complaints of dysphagia and multiple verrucous papules that had developed over the previous year. The diagnosis of esophageal carcinoma was based on upper gastrointestinal radiography and endoscopic examination with biopsy. The clinical syndrome was consistent with the sign of Leser-Trelat associated with esophageal carcinoma. Although radiation therapy and chemotherapy were undertaken, the patient died 8 months later because of the sign of Leser-Trelat in association with squamous cell esophageal carcinoma.
authors.affiliation: First Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Chiba
authors.forename: T
authors.initials: T
authors.lastname: Shitomi
authors.forename: O
authors.initials: O
authors.lastname: Nakano
authors.forename: H
authors.initials: H
authors.lastname: Shimotono
authors.forename: H
authors.initials: H
authors.lastname: Yamada
authors.forename: E
authors.initials: E
authors.lastname: Fujimaki
authors.forename: S
authors.initials: S
authors.lastname: Orii
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: S
authors.initials: S
authors.lastname: Sato
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D017492:Keratosis, Seborrheic / Q000209:etiology*