Reaction of metallothionein with ethylenediamine-N,N,N',N'-tetraacetic acid.
The reactions of various rabbit MTs (Cd7Th, Zn7Th, Hg7Th, Bi7Th, Pb7Th) with EDTA were studied at different pH and EDTA concentrations, and were determined to be pseudo-first-order reactions. The reactions were all divided into two steps: one faster and EDTA-dependent, and the other EDTA-independent. The mechanism is also described in detail. Based on obtained results, the varied induction behaviors of MT formation for those metals are discussed.
Yue
S
S
State Key Laboratory of Coordination Chemistry, Nanjing University, People's Republic of China.
Zhong
W
W
Zhang
B
B
Zhu
L
L
Tang
W
W
D000818:Animals; D004492:Edetic Acid / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008668:Metallothionein / Q000737:chemistry* / Q000378:metabolism; D008670:Metals / Q000737:chemistry / Q000378:metabolism; D011817:Rabbits
D008670:Metals; D008668:Metallothionein; D004492:Edetic Acid