(all trans)-2,4,6,8,10,12-tetradecahexene-1,14-dial, a new pigment from Conidiobolus paulus.
A study of the coloring matter produced by Conidiobolus paulus Drechsler NRRL 2648 on potato-dextrose medium led to the isolation of a new dialdehyde unsaturated metabolite, (all trans)-2,4,6,8,10,12-tetradeca-1,14-hexenedial. The structure was characterized by MS and by 1H- and 13C-NMR. The compound inhibited the growth of the Gram-positive bacterium, Bacillus cereus, and the Gram-negative bacterium, Escherichia coli (MIC values of 10 micrograms and 50 micrograms, respectively).
Vesonder
R F
RF
Mycotoxin Research Unit, National Center for Agricultural Utilization Research USDA, Peoria, Illinois 61604 USA. vesondrf@ncaur1.ncaur.gov
D000447:Aldehydes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001409:Bacillus cereus / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D005658:Fungi / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010860:Pigments, Biological / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
C100549:2,4,6,8,10,12-tetradecahexene-1,14-dial; D000447:Aldehydes; D000900:Anti-Bacterial Agents; D010860:Pigments, Biological