title: [Cysteine cathepsins secreted into the blood as markers of tumor growth].
abstract: Cathepsin H was secreted into the blood plasma of cancer patients before and after surgery. In the mandibular osteoradionecrosis group, there was a tendency for cathepsin H level to decrease, although only in cases free from recurrent tumor growth. Constant levels of cathepsin H were maintained after specific treatment, even in tumor recurrence-free cases. Secretion of such enzymes may be considered a characteristic of tumor-bearing organism. Biochemical assay of cathepsin H level may be used as another procedure for diagnosing different patterns of malignant growth.
authors.forename: A A
authors.initials: AA
authors.lastname: Zhloba
authors.forename: V A
authors.initials: VA
authors.lastname: Dunaevskiĭ
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000097:blood*; D056655:Cathepsin H; D002403:Cathepsins / Q000097:blood*; D003546:Cysteine Endopeptidases; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D009369:Neoplasms / Q000097:blood*; D009374:Neoplasms, Experimental / Q000097:blood; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000097:blood; D051381:Rats
chemical_list: D014408:Biomarkers, Tumor; D002403:Cathepsins; D003546:Cysteine Endopeptidases; C534126:CTSH protein, human; D056655:Cathepsin H; C534127:Ctsh protein, mouse; C534128:Ctsh protein, rat
vernacular_title: Aktivnost' sekretiruemykh form tsisteinovykh katepsinov v krovi v kachestve markera protsessov tkanevogo rosta.