title: Nucleotide sequence of a cDNA coding for cyclophilin of the sea urchin Hemicentrotus pulcherrimus.
abstract: We present the nucleotide sequence of a cDNA coding for cyclophilin homologue of the sea urchin Hemicentrotus pulcherrimus. The 1,755-nucleotide sequence contains a 492-bp open reading frame corresponding to a translation product of 164 amino acids. Comparison of the deduced amino acid sequence with the previous data shows a high degree of conservation (approximately 80% homology). Southern blot analysis of genomic DNA suggests the presence of a multigene for sea urchin cyclophilin. Northern blot analysis indicates a mRNA size of approximately 3 kb and that message is accumulated at blastula stage.
authors.affiliation: Department of Biology, Faculty of Science, Toho University, Funabashi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ohta
authors.forename: T
authors.initials: T
authors.lastname: Nakazawa
mesh_terms: D000591:Amino Acid Isomerases / Q000096:biosynthesis / Q000235:genetics*; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002352:Carrier Proteins / Q000096:biosynthesis / Q000235:genetics*; D018076:DNA, Complementary / Q000235:genetics*; D008969:Molecular Sequence Data; D019696:Peptidylprolyl Isomerase; D012617:Sea Urchins / Q000196:embryology / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D018076:DNA, Complementary; D000591:Amino Acid Isomerases; D019696:Peptidylprolyl Isomerase