[The study of the evolution of laryngeal premalignant lesions].
Hyperkeratosis of the laryngeal epithelium is considered a clinically premalignant lesion that develops into invasive carcinoma in about 7-20% of cases. We reviewed 125 cases of patients with laryngeal keratosis in biopsy obtained by direct laryngocopy over a 10-year period. The evolution of these lesions to malignancy was conditioned by age, the presence of atypias in the initial lesions, and smoking; smoking is a modifiable factor. Surgery is the treatment of choice, with periodic follow-up for three to five years. The literature was reviewed.
Rodríguez García
L
L
Servicio de ORL, Hospital Nuestra Señora de Aránzazu, San Sebastián (Guipúzcoa).
Landa Aranzábal
M A
MA
Rivas Salas
A
A
Abrego Olano
M
M
Algaba Guimera
J
J
D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D007642:Keratosis / Q000503:physiopathology* / Q000601:surgery; D007828:Laryngoscopy; D007830:Larynx / Q000473:pathology* / Q000503:physiopathology* / Q000601:surgery; D007971:Leukoplakia / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects
Estudio evolutivo de lesiones premalignas laríngeas.