title: Bone marrow transplantation retinopathy in the absence of radiation therapy.
abstract: OBJECTIVE
  To describe a case of bone marrow transplantation retinopathy in a patient in the absence of prior radiation therapy.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  Bilateral scotomata developed in a 26-year-old woman because of a retinal microvasculopathy two years after receiving an autologous bone marrow transplantation for acute promyelocytic leukemia. No prior radiation therapy had been given.
  
  
  CONCLUSIONS
  Certain combinations of antimetabolites used during induction and transplantation may themselves be toxic to the retinal microvasculature. Patients who undergo bone marrow transplantation would benefit from regular and complete eye examinations, even in the absence of prior radiation therapy.
authors.affiliation: Francis I. Proctor Foundation, University of California Medical Center, San Francisco 94122, USA. emmett@itsa.ucsf.edu
authors.forename: E T
authors.initials: ET
authors.lastname: Cunningham
authors.forename: A R
authors.initials: AR
authors.lastname: Irvine
authors.forename: H S
authors.initials: HS
authors.lastname: Rugo
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000628:therapy; D011878:Radiotherapy; D015356:Retinal Artery Occlusion / Q000209:etiology*; D012166:Retinal Hemorrhage / Q000209:etiology*; D012607:Scotoma / Q000209:etiology*; D014182:Transplantation, Autologous