title: Laparoscopic and conventional closure of perforated peptic ulcer. A comparison.
abstract: BACKGROUND
  After the first successful laparoscopic closure of a perforated peptic ulcer in 1990, 18 patients with laparoscopic closure were compared to 16 patients with conventional surgery.
  
  
  METHODS
  The endpoint adverse events (complications), pain intensity, operation time, fever, leucocytosis, and duration of hospital stay showed no clinically relevant differences.
  
  
  RESULTS
  Consumption of analgesics was lower in the laparoscopic group.
  
  
  CONCLUSIONS
  Laparoscopic closure of perforated peptic ulcer is technically feasible. The safety of the method and the benefit for the patient need proof by means of a randomized controlled trial.
authors.affiliation: Department of Surgery II, University of Cologne, Krankenhaus Merheim, Ostmerheimer Strasse 200, D-51109 Köln, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Miserez
authors.forename: E
authors.initials: E
authors.lastname: Eypasch
authors.forename: W
authors.initials: W
authors.lastname: Spangenberger
authors.forename: R
authors.initials: R
authors.lastname: Lefering
authors.forename: H
authors.initials: H
authors.lastname: Troidl
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004381:Duodenal Ulcer / Q000150:complications*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000209:etiology / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies; D013276:Stomach Ulcer / Q000150:complications*; D016896:Treatment Outcome