title: Small cell variant of Ki-1 lymphoma associated with myelofibrosis and a novel constitutional chromosomal translocation t(3;4) (q13;q12).
abstract: An unusual case of small cell variant of Ki-1 non-Hodgkin's lymphoma diagnosed one year after an original diagnosis of idiopathic myelofibrosis is reported. On the second occasion, the patient presented with fever, lymphadenopathy and hepatosplenomegaly. A lymph node biopsy specimen confirmed a diagnosis of small cell variant of Ki-1 lymphoma. A repeat bone marrow biopsy specimen showed myelofibrosis with no evidence of lymphomatous infiltration, but cytogenetic studies on blood, bone marrow and skin fibroblasts revealed a novel chromosomal translocation t(3,4)(q13;q12).
authors.affiliation: Department of Clinical Oncology, Chinese University of Hong Kong.
authors.forename: W
authors.initials: W
authors.lastname: Yeo
authors.forename: N
authors.initials: N
authors.lastname: Wong
authors.forename: J
authors.initials: J
authors.lastname: Chow
authors.forename: W C
authors.initials: WC
authors.lastname: Tsoi
authors.forename: P J
authors.initials: PJ
authors.lastname: Johnson
authors.forename: N
authors.initials: N
authors.lastname: Wickham
mesh_terms: D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D002882:Chromosomes, Human, Pair 13; D002893:Chromosomes, Human, Pair 3 / Q000235:genetics*; D002894:Chromosomes, Human, Pair 4 / Q000235:genetics*; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000150:complications / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000150:complications*; D014178:Translocation, Genetic