title: Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.
authors.affiliation: Department of Medicinal Chemistry, School of Pharmacy and Pharmacology, University of Bath, Bath, UK.
authors.forename: L W
authors.initials: LW
authors.lastname: Woo
authors.forename: A
authors.initials: A
authors.lastname: Purohit
authors.forename: M J
authors.initials: MJ
authors.lastname: Reed
authors.forename: B V
authors.initials: BV
authors.lastname: Potter
mesh_terms: D001665:Binding Sites; D001943:Breast Neoplasms / Q000201:enzymology; D003374:Coumarins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008861:Microsomes / Q000201:enzymology; D010920:Placenta / Q000201:enzymology; D013429:Sulfatases / Q000037:antagonists & inhibitors*; D013449:Sulfonamides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: C100463:4-methylcoumarin 7-O-sulfamate; D003374:Coumarins; D004791:Enzyme Inhibitors; D013449:Sulfonamides; C100462:coumarin 7-O-sulfamate; D013429:Sulfatases; C020121:estrone sulfatase