title: The specificity and product of quenching singlet oxygen by 2,2,6,6-tetramethylpiperidine.
abstract: The specificity of 2,2,6,6-tetramethylpiperidine to singlet oxygen was shown using Rose Bengal as a singlet oxygen generator, and Xanthine-Xanthine Oxidase and KO2 as the sources for the superoxide radical. The highest concentration of produced-singlet oxygen occurred at 25% of O2 by Rose Bengal photosensitization. The linewidth of the EPR signal for photosensitized nitroxyl radical, increasing solvent polarity. Deuterated solvents enlarge the EPR signal intensity in a dose-dependent manner. No EPR signal increase was observed in xanthine-xanthine oxidase reaction or KO2 systems, indicating that TEMP does not react with the superoxide anion. Thus, reaction of TEMP with 1O2 is highly specific.
authors.affiliation: Department of Biomedical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg 24061-0442, USA.
authors.forename: L Y
authors.initials: LY
authors.lastname: Zang
authors.forename: F J
authors.initials: FJ
authors.lastname: van Kuijk
authors.forename: B R
authors.initials: BR
authors.lastname: Misra
authors.forename: H P
authors.initials: HP
authors.lastname: Misra
mesh_terms: D003497:Cyclic N-Oxides / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry*; D010880:Piperidines / Q000737:chemistry*; D012395:Rose Bengal / Q000737:chemistry*; D014969:Xanthine Oxidase / Q000737:chemistry
chemical_list: D003497:Cyclic N-Oxides; D005609:Free Radicals; D010880:Piperidines; D012395:Rose Bengal; D014969:Xanthine Oxidase; D010100:Oxygen; C003959:TEMPO