Partial deletion of the long arm of chromosome 5: a fluorescence in situ hybridization study using band-specific painting probes generated by chromosome microdissection.
A series of 17 patients with myeloid disorders and partial deletions of the long arm of chromosome 5 were investigated using fluorescence in situ hybridization with 5q34-q35 region-specific painting probes generated by chromosome microdissection. This approach confirmed that partial 5q deletions are interstitial in all the cases studied. In addition no translocation involving chromosome 5 was detected.
Tigaud
I
I
Unité Inserm 301 et SDI No. 15954 I CNRS, Institut de Génétique Moléculaire, Paris, France.
Charrin
C
C
Berger
R
R
Jonveaux
P
P
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001483:Base Sequence; D002871:Chromosome Banding; D002895:Chromosomes, Human, Pair 5; D015342:DNA Probes; D005260:Female; D017353:Gene Deletion; D005821:Genetic Techniques; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
D015342:DNA Probes