Inhibition of NF kappa B activity by oxidative processes in intact cells mechanism of action of pyrolidine dithiocarbamate and diamide.
Brennan
P
P
Biochemistry Department, Trinity College, Dublin, Ireland.
O'Neill
L A
LA
D000595:Amino Acid Sequence; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001665:Binding Sites; D002460:Cell Line; D017124:Conserved Sequence; D003958:Diamide / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D016328:NF-kappa B / Q000037:antagonists & inhibitors*; D010084:Oxidation-Reduction; D011392:Proline / Q000031:analogs & derivatives* / Q000494:pharmacology; D011518:Proto-Oncogene Proteins / Q000737:chemistry / Q000378:metabolism*; D020569:Proto-Oncogene Proteins c-rel; D017386:Sequence Homology, Amino Acid; D013859:Thiocarbamates / Q000494:pharmacology*; D014407:Tumor Cells, Cultured; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
D000975:Antioxidants; D016328:NF-kappa B; D011518:Proto-Oncogene Proteins; D020569:Proto-Oncogene Proteins c-rel; D013859:Thiocarbamates; D014409:Tumor Necrosis Factor-alpha; D003958:Diamide; C066229:prolinedithiocarbamate; D011392:Proline; D005978:Glutathione