Renal oncocytoma: preoperative diagnosis using technetium 99m sestamibi imaging.
OBJECTIVE
To determine if 99mTc-sestamibi (technetium 99m-methoxyisobutylisonitrile) can be used preoperatively to differentiate renal oncocytomas from other renal masses.


METHODS
We performed 99mTc-sestamibi scans on 6 patients with various renal masses, using a standard technique. The diagnosis in each patient was determined either by radiologic methods.


RESULTS
There was significantly increased uptake in the patient with the renal oncocytoma, whereas the other lesions had decreased uptake in comparison to normal kidney. This was determined visually and by mean pixel analysis.


CONCLUSIONS
Technetium 99m sestamibi scanning appears to have a potential role in the nonoperative diagnosis of renal oncocytomas, in combination with pathologic fine-needle biopsy confirmation. More definitive pathologic experience is required before recommending standard use.
Gormley
T S
TS
Urology Service, William Beaumont Army Medical Center, El Paso, Texas 79920-5001, USA.
Van Every
M J
MJ
Moreno
A J
AJ
D018249:Adenoma, Oxyphilic / Q000000981:diagnostic imaging*; D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi
D017256:Technetium Tc 99m Sestamibi