The addition of tenoxicam to prilocaine for intravenous regional anaesthesia.
The analgesic effects of tenoxicam 20 mg added to prilocaine in a standard Bier's block (group 2) was studied in 45 patients who had their Colles' fractures reduced under intravenous regional anaesthesia, and compared both to a control group (group 1), and to a group who received a standard Bier's block combined with the same dose of tenoxicam given intravenously into the contralateral arm (group 3). Patients in group 2 obtained significantly better analgesia than group 1, as judged by a longer time before first additional analgesia was required (p < 0.05), less total analgesic consumption (p < 0.01), and lower pain scores (p < 0.01). These benefits were not obtained by patients in group 3.
Jones
N C
NC
Department of Anaesthesia, Brook General Hospital, Woolwich, London.
Pugh
S C
SC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000765:Anesthesia, Conduction; D000771:Anesthesia, Intravenous; D000779:Anesthetics, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D003100:Colles' Fracture / Q000601:surgery; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011318:Prilocaine; D011446:Prospective Studies
D000779:Anesthetics, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011318:Prilocaine; D010894:Piroxicam; C032801:tenoxicam