title: Benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine: biological activities and dental care applications.
abstract: This article reviews chemical, pharmacological, and toxicological research relating to two principal benzo[c]phenanthridine alkaloids, namely sanguinarine and chelerythrine, in the period 1980-1994. The medical applications of these alkaloids in relation to their biological activities are discussed.
authors.affiliation: Institute of Medical Chemistry, Faculty of Medicine, Palacký University Olomouc, Czech Republic.
authors.forename: D
authors.initials: D
authors.lastname: Walterová
authors.forename: J
authors.initials: J
authors.lastname: Ulrichová
authors.forename: I
authors.initials: I
authors.lastname: Válka
authors.forename: J
authors.initials: J
authors.lastname: Vicar
authors.forename: C
authors.initials: C
authors.lastname: Vavrecková
authors.forename: E
authors.initials: E
authors.lastname: Táborská
authors.forename: R J
authors.initials: RJ
authors.lastname: Harjrader
authors.forename: D L
authors.initials: DL
authors.lastname: Meyer
authors.forename: H
authors.initials: H
authors.lastname: Cerná
authors.forename: V
authors.initials: V
authors.lastname: Simánek
mesh_terms: D000470:Alkaloids / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D053119:Benzophenanthridines; D006801:Humans; D007546:Isoquinolines; D009067:Mouthwashes / Q000494:pharmacology / Q000627:therapeutic use; D009910:Oral Hygiene; D010617:Phenanthridines / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000470:Alkaloids; D053119:Benzophenanthridines; D007546:Isoquinolines; D009067:Mouthwashes; D010617:Phenanthridines; C005705:sanguinarine; C016299:chelerythrine