title: Survival of adult patients with head and neck soft tissue sarcomas.
abstract: A retrospective review and survival analysis is presented of 58 adult patients referred between 1963 and 1993 for treatment of a head and neck soft tissue sarcoma. The 5 year overall and disease-free survival was 60% and 52% respectively. Univariate analysis indicated that age, positive margins, bone invasion, distant metastases, single modality treatment, histological grading, sites below the deep fascia and size might be predictors of survival. On multivariate analysis, age, histological grade, distant metastases, site and referral for recurrent disease emerged as prognostic factors known before treatment. By including variables known after treatment, age remained the most important independent prognostic factor followed by the presence of free margins, histological grading and distant metastases at presentation.
authors.affiliation: Department of Otolaryngology/Head and Neck Surgery, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Hospital), Amsterdam, The Netherlands.
authors.forename: M D
authors.initials: MD
authors.lastname: Dijkstra
authors.forename: A J
authors.initials: AJ
authors.lastname: Balm
authors.forename: F V
authors.initials: FV
authors.lastname: Coevorden
authors.forename: R T
authors.initials: RT
authors.lastname: Gregor
authors.forename: A A
authors.initials: AA
authors.lastname: Hart
authors.forename: F J
authors.initials: FJ
authors.lastname: Hilgers
authors.forename: R B
authors.initials: RB
authors.lastname: Keus
authors.forename: B M
authors.initials: BM
authors.lastname: Loftus
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D018223:Dermatofibrosarcoma / Q000401:mortality* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012535:Scalp / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000401:mortality* / Q000473:pathology; D015996:Survival Rate