High-potency topical corticosteroid rapidly decreases histamine-induced itch but not thermal sensation and pain in human beings.
Yosipovitch
G
G
Department of Dermatology, University of California, San Francisco Medical Center 94143, USA.
Szolar
C
C
Hui
X Y
XY
Maibach
H
H
D000279:Administration, Cutaneous; D000328:Adult; D000704:Analysis of Variance; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002990:Clobetasol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D005938:Glucocorticoids; D006632:Histamine / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009824:Ointments; D010146:Pain / Q000503:physiopathology*; D017288:Pain Threshold / Q000187:drug effects; D010919:Placebos; D011537:Pruritus / Q000139:chemically induced / Q000517:prevention & control*; D012684:Sensory Thresholds / Q000187:drug effects; D013697:Thermosensing / Q000187:drug effects*
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D009824:Ointments; D010919:Placebos; D006632:Histamine; D002990:Clobetasol