Anaphylactic reactions to high molecular weight dextran during hysteroscopic surgery.
Dextran solutions are used for plasma expanders, thromboembolic prevention, and as a distention and irrigating fluid for various endoscopic procedures. High-molecular-weight dextrans are accompanied by significant side effects including pulmonary edema, allergic reactions, renal failure, and altered coagulation profiles. The following is a case report of an allergic reaction to 32% Dextran-70 during a hysteroscopic examination and biopsy of a 67-year-old woman. A discussion follows outlining the adverse effects of high viscosity dextrans alerting the anesthetist to the possibilities of intraoperative complications.
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D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced* / Q000628:therapy; D003911:Dextrans / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D010535:Laparoscopy; D008970:Molecular Weight; D010952:Plasma Substitutes / Q000009:adverse effects*
D003911:Dextrans; D010952:Plasma Substitutes