title: [Serologic screening on nasopharyngeal cancer in 338,868 persons in 21 cities and counties of Guangxi Region, China].
abstract: Serological screening on nasopharyngeal cancer in 338,868 persons living in 21 cities and counties of Guangxi Zhuang Autonomous Region was carried out from January 1991 to September 1993. Results showed 9367 persons were positive for IgA antibodies to Epstein-Barr virus (EBV) capsid antigen, and 306 of them positive for IgA to EBV early antigen. One hundred and thirteen cases of nasopharyngeal cancer were detected in the former with 100 cases (88.5%) in the early stage, and 63 cases in the latter with 58 (92.1%) cases in the early stage. It suggested certain relationship existed between EBV and nasopharyngeal cancer, and serologic screening could be beneficial for secondary prevention of it.
authors.affiliation: Wuzhou Cancer Institute, Guangxi.
authors.forename: H
authors.initials: H
authors.lastname: Deng
authors.forename: Z
authors.initials: Z
authors.lastname: Zhao
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000276:immunology; D002213:Capsid / Q000276:immunology; D036022:Capsid Proteins; D002681:China / Q000453:epidemiology; D005260:Female; D006566:Herpesviridae Infections; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000517:prevention & control* / Q000821:virology; D016036:Seroepidemiologic Studies; D014412:Tumor Virus Infections
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D036022:Capsid Proteins; C041788:Epstein-Barr viral capsid antigen; C033305:Epstein-Barr virus early antigen; D007070:Immunoglobulin A