[Occurrence of thyroid gland carcinoma in Graves-Basedow disease].
Among 319 patients with Graves-Basedow disease who were operated upon in surgical department of The Institute of Endocrinology in Belgrade between 1978 and 1990, thyroid carcinoma was found in 15 cases (4.7%). In 10 patients carcinoma was suspected before operation because of the node in diffuse goiter, while in 5 patients carcinoma was found unexpectedly. Tumor was smaller than 1 sm in only one patient. Nine patients had papillary carcinoma, 4 had follicular and 2 had medullary carcinoma. One patient with medullary carcinoma had been treated previously with radioactive iodine. In 2 patients carcinoma was found in recurrent goiter after primary operation, patients with thyroid carcinoma in Graves-Basedow disease were averaging about 10 years older than other patients with Graves-Basedow disease treated surgically.
Diklić
A
A
Institute of Endocrinology, University Clinical Center, Belgrade.
Paunović
I
I
Batev
N
N
Malenković
V
V
Havelka
M
M
Janković
R
R
D000328:Adult; D002277:Carcinoma / Q000150:complications*; D005260:Female; D006111:Graves Disease / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000150:complications*
Ucestalost karcinoma stitaste zlezde u Graves-Basedowljevoj bolesti.