title: Splenectomy in a general hospital.
abstract: Splenectomy is often performed in patients with malignant disease or trauma who are at a high risk of complications. In the long term, it increases the risk of infection by encapsulated bacteria. An audit was performed to determine the reasons for splenectomy in a district general hospital, to review the results and complications of surgery, and to see how often the patients were prescribed antibacterial prophylaxis. Twenty-eight patients underwent splenectomy in 3 years. The indication was haematological disease in 13 and trauma in four. In the remaining nine the spleen was removed either as part of a radical gastrectomy or during some other abdominal procedure. Six of the 28 patients had died, one within 30 days from disseminated intravascular coagulopathy following an emergency gastrectomy and splenectomy for haematemesis, two from progressive haematological malignant disease, two from non-haematological malignancy, and one from bronchopneumonia. Of the nine patients (32%) with complications, three required a further laparotomy. Most patients had been prescribed pneumococcal vaccine (85%) and prophylactic antibiotics (93%).
authors.affiliation: Department of General Surgery, Wexham Park Hospital, Berkshire, England.
authors.forename: J M
authors.initials: JM
authors.lastname: Glass
authors.forename: J M
authors.initials: JM
authors.lastname: Gilbert
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D004739:England; D005260:Female; D006402:Hematologic Diseases / Q000601:surgery; D006767:Hospitals, District; D006769:Hospitals, General; D006801:Humans; D007114:Immunization / Q000706:statistics & numerical data; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D022242:Pneumococcal Vaccines; D013154:Spleen / Q000293:injuries; D013156:Splenectomy / Q000009:adverse effects / Q000401:mortality; D013296:Streptococcus pneumoniae / Q000276:immunology*
chemical_list: D000900:Anti-Bacterial Agents; D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines