title: Hair lead levels related to children's classroom attention-deficit behavior.
abstract: The goal of this study was to evaluate the relationship between hair lead levels of children and their attention-deficit behaviors in the classroom. Scalp hair specimens were obtained from 277 first-grade pupils, teachers completed the abbreviated Boston Teacher's Rating Scale for rating classroom attention-deficit behavior, and parents completed a short questionnaire. The children's hair lead concentrations ranged from less than 1 to 11.3 ppm (microg/g). The striking dose-response relationship between levels of lead and negative teacher ratings remained significant after controlling for age, ethnicity, gender, and socioeconomic status. An even stronger relationship existed between physician-diagnosed attention-deficit hyperactivity disorder and hair lead in the same children. There was no apparent 'safe' threshold for lead. Scalp hair should be considered a useful clinical and epidemiologic approach for the measurement of chronic low-level lead exposure in children.
authors.affiliation: School of Public Health, University of Massachusetts, Amherst, USA.
authors.forename: R W
authors.initials: RW
authors.lastname: Tuthill
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007854:Lead / Q000032:analysis*; D016015:Logistic Models; D008297:Male; D010290:Parents; D013223:Statistics as Topic; D011795:Surveys and Questionnaires; D013663:Teaching
chemical_list: D007854:Lead