Epidemiology and psychopharmacology of anxiety in medical patients.
A wide variety of comorbid anxiety disorders have been described in patients with medical disorders, with the most common being adjustment disorder with anxiety, panic disorder, and generalized anxiety disorder. This article briefly reviews representative studies of the prevalence of anxiety disorders in several medical conditions, placing emphasis on cardiovascular, pulmonary, cerebrovascular, and dermatologic disease. Psychotropic medications appropriate for the treatment of anxiety disorders in these medical-psychiatric populations (benzodiazepines, cyclic antidepressants, and buspirone) as well as beta-adrenergic blocking agents and antihistamines are discussed with an emphasis on pharmacokinetic and drug interactions of major clinical importance for the medically ill patient.
Stoudemire
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Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Ga, USA.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000139:chemically induced / Q000188:drug therapy* / Q000453:epidemiology*; D001569:Benzodiazepines; D002065:Buspirone / Q000627:therapeutic use; D015897:Comorbidity; D004813:Epidemiology; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use; D015995:Prevalence
D000319:Adrenergic beta-Antagonists; D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D006634:Histamine H1 Antagonists; D008996:Monoamine Oxidase Inhibitors; D001569:Benzodiazepines; D002065:Buspirone