Vulval cicatricial pemphigoid may mimic lichen sclerosus.
We report two patients with vulval signs suggestive of lichen sclerosus. This diagnosis was never substantiated histologically and microscopic appearances were non-specific. In both cases the development of lesions at other cutaneous and mucosal sites alerted us to the possibility that the autoimmune bullous disease, cicatricial pemphigoid, accounted for the entire clinical picture. Lichen sclerosus and cicatricial pemphigoid are distinctive conditions which clinically are usually readily differentiated on cutaneous surfaces. When the site of presentation is on the vulva the clinical picture may become obscure and this can lead to diagnostic confusion. It is important to establish the correct diagnosis as this predicts the clinical course and prognosis in each case.
Marren
P
P
Department of Dermatology, Oxford Radcliffe Hospitals, U.K.
Walkden
V
V
Mallon
E
E
Wojnarowska
F
F
D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000473:pathology*; D010390:Pemphigoid, Benign Mucous Membrane / Q000473:pathology*; D014845:Vulvar Diseases / Q000473:pathology*