Hapten resistant dextran induced ARDS reaction following intracoronary stent deployment.
A case of dextran induced adult respiratory distress syndrome is used to illustrate the most serious complication of dextran usage during intracoronary stent placement. This reaction occurred despite premedication with the hapten dextran 1. Mechanisms of dextran induced complications are discussed. A mechanism for hapten resistant dextran reactions is postulated. Suggestions to prevent such reactions are made.
Gossman
D E
DE
Section of Cardiology, Lahey Hitchcock Clinic, Burlington, MA 01805, USA.
Schneider
F
F
D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D003331:Coronary Vessels; D003911:Dextrans / Q000009:adverse effects* / Q000627:therapeutic use; D004351:Drug Resistance; D005260:Female; D006241:Haptens / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000139:chemically induced* / Q000517:prevention & control; D015607:Stents
D000925:Anticoagulants; D003911:Dextrans; D006241:Haptens