Ethylene glycol acute poisoning treatment results in Kraków in the years 1990-1994.
An analysis of ethylene glycol acute intoxication treatment results was performed in a group of 36 patients hospitalized within a five year period. Mean serum and urine glycol concentrations in the analyzed population ranged from 0-851 mg/dl (mean = 130 mg/dl) and from 12.4 to 930.0 mg/dl (mean 333 mg/dl), respectively. At the time of admission to the clinic 15 of 36 patients were deeply unconscious and mean acid-base balance values were as follows: pH 6.99, pCO2 16.7 mmHg, pO2 140.1 mmHg, HCO3 6.36 mmol/l, BE -29.6 mmol/l. Because of respiratory failure 21/36 patients (58.3%) required controlled ventilation and 24/36 (66.7%) underwent dialysis. Sixteen patients (44.4%) developed acute renal failure. Mean hospitalization period was 16 days (1-53). Eighteen patients (50%) died. The direct death mechanism in 15 patients (83.3%) was asystolia and in the remaining individuals other circulatory disturbances. The main reasons of high mortality rate were multiple organ damages secondary to severe metabolic acidosis.
Stompór
T
T
Department of Nephrology Collegium Medicum, Jagiellonian University, Kraków, Poland.
Szymczakiewicz-Multanowska
A
A
Sułowicz
W
W
Pach
J
J
Groszek
B
B
Winnik
L
L
Kuźniewski
M
M
D000137:Acid-Base Imbalance / Q000209:etiology / Q000628:therapy*; D000138:Acidosis / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy*; D000293:Adolescent; D000328:Adult; D002423:Cause of Death; D062787:Drug Overdose; D019855:Ethylene Glycol; D005026:Ethylene Glycols / Q000097:blood / Q000506:poisoning* / Q000652:urine; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011044:Poland; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*; D015996:Survival Rate; D016896:Treatment Outcome
D005026:Ethylene Glycols; D019855:Ethylene Glycol