The haemodynamic correlations of the cardiopulmonary flow index, a relatively non-invasive technique for diagnosis of myocardial pump insufficiency.
The cardiopulmonary flow index (CPFI) is the ratio of cardiopulmonary blood volume to stroke volume. OBJECTIVE. To compare the CPFI derived from a first-pass radiocardiogram and electrocardiogram with the usual haemodynamic measurements obtained by bedside catheterisation. DESIGN. Sixty-one patients in a coronary care unit who had flow-directed pulmonary artery catheterisation for clinical indications had a CPFI recorded together with the usual haemodynamic measurements and calculations. RESULTS. In patients with myocardial pump failure without significant pulmonary disease, linear regression analysis indicated that the best fit for the CPFI could be obtained with a model that used the inverse of stroke index and pulmonary capillary wedge pressure as independent variables. Ninety-six per cent of the variation in CPFI can be explained by variations in pulmonary capillary wedge pressure and stroke index. The CPFI correlated less well with these variables in patients with concomitant lung disease. CONCLUSION. The CPFI is a potentially useful and relatively non-invasive index of haemodynamic function in acutely ill patients without significant pulmonary disease.
van der Walt
J J
JJ
Department of Physiology, Potchefstroom University, North-West Province.
van Aarde
M N
MN
van Rooyen
J M
JM
Millar
R N
RN
Obel
I W
IW
Levin
J
J
D001810:Blood Volume / Q000502:physiology*; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000503:physiopathology; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D011652:Pulmonary Circulation / Q000502:physiology*; D013318:Stroke Volume / Q000502:physiology*