[The morphological changes in the liver in experimentally induced hypercholesterolemia].
The authors examined the liver of 20 rabbits "Newzeland white" and "Chinchila", undergone atherogenic diet with cholesterol (0.3-0.5 g/kg body weight) for 30 and 60 days. They determined cholesterol, lipids, triglicerides and beta-lipoproteins in the serum. The morphologic study revealed accumulation of cholesterol in the hepatocytes, fibrosis, proliferation of the bile ducts and signs of hepatic cirrhosis.
Boshnakova
Ts
Ts
Department of Pathological Anatomy, Higher Medical School, Sofia.
Georgiev
A
A
Strashimirov
D
D
D000818:Animals; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D006937:Hypercholesterolemia / Q000097:blood / Q000139:chemically induced / Q000473:pathology*; D008055:Lipids / Q000097:blood; D008099:Liver / Q000648:ultrastructure*; D008854:Microscopy, Electron; D011817:Rabbits; D013997:Time Factors
D002791:Cholesterol, Dietary; D008055:Lipids
Morfologichni promeni v cherniia drob pri eksperimentalno predizvikana khiperkholesterolemiia.