title: Risperidone appears safe in patients with antipsychotic-induced blood dyscrasias.
abstract: Two cases are reported who developed blood dyscrasias, involving neutropenia and thrombocytopenia respectively, after treatment with phenothiazine and butyrophenone antipsychotics. A subsequent good therapeutic response was obtained with risperidone. It is suggested that risperidone may be considered as an alternative when blood dyscrasias occur with classic antipsychotics.
authors.affiliation: Wakari Hospital, Dunedin School of Medicine, University of Otago Medical School, New Zealand.
authors.forename: T
authors.initials: T
authors.lastname: Mahmood
authors.forename: T
authors.initials: T
authors.lastname: Silverstone
authors.forename: B
authors.initials: B
authors.lastname: Spittle
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002090:Butyrophenones; D005260:Female; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000139:chemically induced* / Q000517:prevention & control; D010640:Phenothiazines; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000139:chemically induced* / Q000517:prevention & control; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy
chemical_list: D014150:Antipsychotic Agents; D002090:Butyrophenones; D010640:Phenothiazines; D018967:Risperidone