title: [Morphological, microstereological and immunohistoenzymological studies of the jejuni of infants with recurrent constructive bronchitis and chronic diarrhea due to cow's milk protein allergy].
abstract: Morphological, microstereological and immunohistoenzymatic technique were used to assess jejunal biopsy samples obtained from 17 infants suffering from chronic diarrhoea and bronchitis spastica (the study group), and 5 infants with chronic diarrhoea and weight deficiency (group G). In the first group, histopathological studies revealed a small degree of villous atrophy (II degree) in 12/17 of cases, and in 5/17, a moderate atrophy (III degree). The microstereological technique disclosed infiltration of the submucosa which was significantly more marked in the study group as compared with group G (p < 0.05). Positive immunohistoenzymatic reactions in mononuclear cells of the submucosa infiltration were observed in all cases, but was more distinct in the first group. The results of the study show jejunal biopsy to be helpful in confirming the allergic etiology of the disease in the study group.
authors.affiliation: I Klinika Chorób Dzieci Akademii Medycznej w Lodzi.
authors.forename: K
authors.initials: K
authors.lastname: Wasowska-Królikowska
authors.forename: A
authors.initials: A
authors.lastname: Charubczyk
authors.forename: W
authors.initials: W
authors.lastname: Kozłowski
authors.forename: J
authors.initials: J
authors.lastname: Bodalski
mesh_terms: D000818:Animals; D001991:Bronchitis / Q000209:etiology*; D002908:Chronic Disease; D003238:Connective Tissue / Q000737:chemistry; D003967:Diarrhea / Q000209:etiology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000097:blood; D007231:Infant, Newborn; D007583:Jejunum / Q000737:chemistry*; D008214:Lymphocytes; D008892:Milk / Q000009:adverse effects*; D016269:Milk Hypersensitivity / Q000209:etiology*; D008894:Milk Proteins / Q000009:adverse effects*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008894:Milk Proteins; D007073:Immunoglobulin E
vernacular_title: Badania morfologiczne, mikrostereologiczne i immunohistoenzymatyczne w błonie śluzowej jelita czczego u niemowlat z nawracajacymi obturacyjnymi zapaleniami oskrzeli i towarzyszaca biegunka przewlekła na tle uczulenia na białka mleka krowiego.