title: Paracetamol prescribing--an epidemic?
abstract: BACKGROUND
  Although we are uncertain of its therapeutic mechanism, paracetamol is seen as a safe drug, especially for children. However, adult fatalities from overdose and its association with hepatotoxicity have cast doubt on its safety.
  
  
  OBJECTIVE
  We aimed to establish the prescribing patterns of paracetamol in the United Arab Emirates (UAE).
  
  
  METHODS
  The prescribing patterns in the UAE for paracetamol were studied by obtaining information on national utilization and recording in detail the pattern of prescribing in one primary health care centre.
  
  
  RESULTS
  Paracetamol was included in 35.5% of all prescriptions from the study practice. Of these, 58.5% were for children under 12 years of age and overall 13.5% were for those infants under one year of age.
  
  
  CONCLUSIONS
  National prescribing utilization is in keeping with the prescribing patterns of the index practice. Paracetamol prescribing is reaching epidemic proportions and the potential dangers of hepatotoxicity and the inhibition of the immune response in children are discussed.
authors.affiliation: Faculty of Medicine & Health Sciences, UAE University, Al Ain, United Arab Emirates.
authors.forename: K P
authors.initials: KP
authors.lastname: Dawson
authors.forename: S
authors.initials: S
authors.lastname: McIlvenny
authors.forename: S
authors.initials: S
authors.lastname: Quinn
authors.forename: D W
authors.initials: DW
authors.lastname: Harron
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use*; D000328:Adult; D017677:Age Distribution; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D017723:Drug Utilization Review; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010818:Practice Patterns, Physicians' / Q000592:standards / Q000706:statistics & numerical data*; D013488:Suppositories; D013607:Tablets; D014479:United Arab Emirates
chemical_list: D018712:Analgesics, Non-Narcotic; D013488:Suppositories; D013607:Tablets; D000082:Acetaminophen