title: Adult-onset complex partial seizures as the presenting sign in colpocephaly: MRI and PET correlates.
abstract: In a 30-year-old man, adult-onset complex partial seizures were associated with colpocephaly as evident from magnetic resonance images. The structurally normal lateral neocortex of the right temporal lobe showed a severe reduction in regional glucose consumption corresponding to the epileptic focus as judged from the surface electroencephalogram. In contrast to previously reported patients, this patient had no focal neurological signs, and neuropsychological testing revealed normal general intelligence. Thus, this patient adds a benign variant to the clinical spectrum of this cerebral developmental disorder.
authors.affiliation: Department of Neurology, Heinrich-Heine-University Düsseldorf, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Wunderlich
authors.forename: G
authors.initials: G
authors.lastname: Schlaug
authors.forename: L
authors.initials: L
authors.lastname: Jäncke
authors.forename: R
authors.initials: R
authors.lastname: Benecke
authors.forename: R J
authors.initials: RJ
authors.lastname: Seitz
mesh_terms: D000328:Adult; D001921:Brain / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007360:Intelligence; D008279:Magnetic Resonance Imaging; D008297:Male; D013702:Temporal Lobe / Q000378:metabolism; D014055:Tomography, Emission-Computed
chemical_list: D005947:Glucose