Abnormal glomerular basement membrane in idiopathic multicentric osteolysis.
The primary cause of nephropathy in idiopathic multicentric osteolysis is as yet unknown. We report a young girl with idiopathic multicentric osteolysis and nephropathy. An abnormal glomerular basement membrane was the only abnormality found in a renal biopsy taken 2 years before the development of end-stage renal failure. We believe that this biopsy finding represents or is related to the unknown primary lesion causing nephropathy in idiopathic multicentric osteolysis.
Bakker
S J
SJ
Department of Nephrology, University Hospital Maastricht, The Netherlands.
Vos
G D
GD
Verschure
P D
PD
Mulder
A H
AH
Tiebosch
A T
AT
D001485:Basement Membrane / Q000648:ultrastructure; D001706:Biopsy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000473:pathology*; D007678:Kidney Glomerulus / Q000648:ultrastructure*; D008854:Microscopy, Electron; D010015:Osteolysis, Essential / Q000150:complications*