Neural systems for tactual memories.
1. The aim of this study was to investigate the neural systems involved in the memory processing of experiences through touch. 2. Regional cerebral blood flow was measured with positron emission tomography by means of the water bolus H2(15)O methodology in human subjects as they performed tasks involving different levels of tactual memory. In one of the experimental tasks, the subjects had to palpate nonsense shapes to match each one to a previously learned set, thus requiring constant reference to long-term memory. The other experimental task involved judgements of the recent recurrence of shapes during the scanning period. A set of three control tasks was used to control for the type of exploratory movements and sensory processing inherent in the two experimental tasks. 3. Comparisons of the distribution of activity between the experimental and the control tasks were carried out by means of the subtraction method. In relation to the control conditions, the two experimental tasks requiring memory resulted in significant changes within the posteroventral insula and the central opercular region. In addition, the task requiring recall from long-term memory yielded changes in the perirhinal cortex. 4. The above findings demonstrated that a ventrally directed parietoinsular pathway, leading to the posteroventral insula and the perirhinal cortex, constitutes a system by which long-lasting representations of tactual experiences are formed. It is proposed that the posteroventral insula is involved in tactual feature analysis, by analogy with the similar role of the inferotemporal cortex in vision, whereas the perirhinal cortex is further involved in the integration of these features into long-lasting representations of somatosensory experiences.
Bonda
E
E
Montreal Neurological Institute, McGill University, Quebec, Canada.
Petrides
M
M
Evans
A
A
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000502:physiology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005106:Exploratory Behavior / Q000502:physiology*; D005260:Female; D006801:Humans; D008568:Memory / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D014055:Tomography, Emission-Computed; D014110:Touch / Q000502:physiology*