title: Surgical commissurotomy of the aortic valve: outcome of open valvotomy in neonates with critical aortic stenosis.
abstract: Early intervention is necessary in neonates with critical aortic stenosis. The advent of alternate therapy, particularly balloon aortic valvuloplasty, requires a reappraisal of the traditional surgical approach, including the efficacy of initial transvalvar gradient reduction and freedom from recurrence of obstruction in the longer term. This report describes a series of 33 consecutive infants who underwent surgical aortic valvotomy in the first month of life. The hospital mortality was 18 percent with a 5-year probability of survival of 66 percent (90 percent CI, 50 percent to 79 percent). Fourteen reinterventions, nine reoperations and five balloon dilatations, were required at a median age of 0.8 years (range 9 days to 6 years). Three patients died after reintervention (one early and two late). The median follow-up time was 5.8 years (range 0.2 to 14 years). At last follow-up Doppler investigation the average Doppler mean and peak gradients were 34 mm Hg and 18 mm Hg, respectively. Open valvotomy in neonatal aortic valve stenosis allows the use of an appropriate surgical approach with low initial mortality and satisfactory 5-year freedom from reintervention.
authors.affiliation: Department of Cardiology, Royal Children's Hospital, Melbourne, Australia.
authors.forename: H P
authors.initials: HP
authors.lastname: Gildein
authors.forename: S
authors.initials: S
authors.lastname: Kleinert
authors.forename: R G
authors.initials: RG
authors.lastname: Weintraub
authors.forename: J L
authors.initials: JL
authors.lastname: Wilkinson
authors.forename: T R
authors.initials: TR
authors.lastname: Karl
authors.forename: R B
authors.initials: RB
authors.lastname: Mee
mesh_terms: D001024:Aortic Valve Stenosis / Q000150:complications / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D002404:Catheterization; D017052:Hospital Mortality; D006801:Humans; D007231:Infant, Newborn; D012086:Reoperation; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome