title: [Prednisolone acetate reference standard (Control 941) of the National Institute of Health Sciences].
abstract: The raw material for prednisolone acetate was tested for preparation of the "Prednisolone Acetate Reference Standard (Control 941)". Analytical data obtained were as follows: melting point, 237.5 degrees C (decomposition); UV and infrared spectra, the same as those for JP Prednisolone Acetate Reference Standard (Control 903), respectively; specific absorbance at lambda max E1%1cm = 379; optical rotation, [alpha]20D = +115.2 degrees; thin-layer chromatography and high-performance liquid chromatography (HPLC), no impurities were detected, respectively; assay, 100.8% by HPLC. Based on the above results, the candidate material was authorized as the Japanese Pharmacopoeia Reference Standard (Control 941).
authors.forename: A
authors.initials: A
authors.lastname: Kitajima
authors.forename: K
authors.initials: K
authors.lastname: Maekawa
authors.forename: K
authors.initials: K
authors.lastname: Yoshii
authors.forename: H
authors.initials: H
authors.lastname: Komatsu
authors.forename: T
authors.initials: T
authors.lastname: Tanimoto
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards; D011239:Prednisolone / Q000031:analogs & derivatives* / Q000032:analysis / Q000592:standards
chemical_list: C009935:prednisolone acetate; D011239:Prednisolone