Multiple roles for DNA methylation in gametic imprinting.
Allele-specific DNA methylation has been observed for all tested imprinted genes and has a clear role in the imprinting mechanism. It remains to be resolved whether this role is to act as the gametic imprinting signal or to cause or maintain allele-specific expression.
Neumann
B
B
Institute of Molecular Pathology, Vienna, Austria.
Barlow
D P
DP
D000818:Animals; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D018392:Genomic Imprinting / Q000502:physiology*; D006801:Humans; D008322:Mammals / Q000235:genetics*; D008745:Methylation
D004247:DNA