[Mechanism of action of sennosides].
A review of the recent progress in the study of the mode of action of the sennosides, the active constituents of the senna drug, is presented. An interaction between rhein anthrone, the active metabolite of the sennosides, and the immune cells of the colon is suggested as a base for laxative activity.
Lemli
J
J
Termeredellelaan, Winksele Belgique.
D000880:Anthraquinones / Q000494:pharmacology*; D002400:Cathartics / Q000494:pharmacology*; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects; D012676:Senna Extract
D000880:Anthraquinones; D002400:Cathartics; D012676:Senna Extract
Mécanisme d'action des sennosides.