title: Total body water measurement in renal insufficiency.
abstract: Total body water was measured in 15 children with renal insufficiency (glomerular filtration rate < 25 ml/min per 1.73 m2) using deuterium oxide dilution. Total body water was also measured using bioelectrical impedance and skinfold anthropometry in the same 15 children. There was a linear correlation (r = 0.98, P < 0.01) between total body water measured by deuterium and height2/impedance. The 95% confidence limits for estimates of total body water were -1.5 to 0.9 for impedance and 0.65-3.16 l for skinfold anthropometry when compared with deuterium dilution. Bioelectrical impedance estimation of total body water is better than the current existing non-invasive method of skinfold anthropometry.
authors.affiliation: Academic Unit of Paediatrics and Child Health, St. James's University Hospital, Leeds, UK.
authors.forename: M G
authors.initials: MG
authors.lastname: Bradbury
authors.forename: J T
authors.initials: JT
authors.lastname: Brocklebank
authors.forename: S W
authors.initials: SW
authors.lastname: Smye
authors.forename: P S
authors.initials: PS
authors.lastname: Davies
mesh_terms: D000293:Adolescent; D001825:Body Fluid Compartments / Q000502:physiology; D001834:Body Water / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D003903:Deuterium; D017097:Electric Impedance; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007223:Infant; D008297:Male; D012044:Regression Analysis; D051437:Renal Insufficiency / Q000378:metabolism* / Q000503:physiopathology; D012885:Skinfold Thickness
chemical_list: D003903:Deuterium