[An analysis of the mutations in the mucoviscidosis gene: the origin and distribution of the delF508 major mutation in Ukraine].
Seven mutations in CFTR gene have been screened in patients with cystic fibrosis from Ukraine. The frequency of major mutation delF508 among patients and healthy donors from different regions was studied. Data of age, origin and possible ways of spreading of this mutation in Ukraine have been discussing.
Livshits
L A
LA
Kravchenko
S A
SA
Musienko
S I
SI
Maliarchuk
S G
SG
D002648:Child; D003550:Cystic Fibrosis / Q000453:epidemiology / Q000235:genetics*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics*; D005091:Exons / Q000235:genetics; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D006239:Haplotypes / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D009154:Mutation / Q000235:genetics*; D012016:Reference Values; D014455:Ukraine / Q000453:epidemiology
C505032:CFTR protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator
Analiz mutatsiĭ v gene mukovistsidoza: proiskhozhdenie i rasprostranenie mazhornoĭ mutatsiii delF508 v Ukraine.