title: Immunocytochemical localization of androgen receptor in the comb, uropygial gland, testis, and epididymis in the domestic chicken.
abstract: Nuclear, but not cytoplasmic androgen receptors (AR), were localized immunocytochemically in the comb, uropygial (preen) gland, testis, and epididymis of juvenile and adult cockerels. Androgen receptor immunoreactivity (AR-ir) was seen in the comb, in the stratum germinativum of the epidermis and in fibromucoid cells in the dermis in juvenile and adult cockerels. AR-ir was observed in the glandular epithelial (sebum-producing) cells lining the peripheral and middle sections of the tubules in the uropygial gland. AR-ir was not detected in innermost part of the tubules which conduct the sebum to the surface of the skin. AR-ir labeling was not observed in the uropygial gland of juveniles. In the testis, AR-ir was seen in the Leydig cells, in adults but not juveniles. The epithelial cells lining the tubules in the epididymis contained AR-ir in both juveniles and adults.
authors.affiliation: Division of Development and Reproduction, Roslin Institute (Edinburgh), Midlothian.
authors.forename: B A
authors.initials: BA
authors.lastname: Shanbhag
authors.forename: P J
authors.initials: PJ
authors.lastname: Sharp
mesh_terms: D000375:Aging / Q000378:metabolism; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D002645:Chickens / Q000378:metabolism*; D003129:Comb and Wattles / Q000166:cytology / Q000378:metabolism; D004822:Epididymis / Q000166:cytology / Q000378:metabolism; D007150:Immunohistochemistry; D008297:Male; D011944:Receptors, Androgen / Q000378:metabolism*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D012627:Sebaceous Glands / Q000166:cytology / Q000378:metabolism; D013737:Testis / Q000166:cytology / Q000378:metabolism
chemical_list: D011944:Receptors, Androgen; D018160:Receptors, Cytoplasmic and Nuclear