Severe combined immunodeficiency due to a defect in the tyrosine kinase ZAP-70.
Elder
M E
ME
Department of Pediatrics, University of California, San Francisco 94143, USA.
D000595:Amino Acid Sequence; D001483:Base Sequence; D018076:DNA, Complementary / Q000235:genetics; D005260:Female; D016368:Frameshift Mutation; D006801:Humans; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D010375:Pedigree; D011505:Protein-Tyrosine Kinases / Q000235:genetics* / Q000276:immunology; D017384:Sequence Deletion; D016511:Severe Combined Immunodeficiency / Q000201:enzymology* / Q000235:genetics* / Q000276:immunology; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology
D018076:DNA, Complementary; D011505:Protein-Tyrosine Kinases