title: Changes in NADPH diaphorase activity in forebrain structures of the laminae terminalis after chronic dehydration.
abstract: The effect of 3-day chronic dehydration on nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-diaphorase) histochemical staining in forebrain circumventricular structures was investigated in the rat. Increased number and/or intensity of staining of NADPH-diaphorase positive neurons was observed in subfornical organ, organum vasculosum of the laminae terminalis, and median preoptic nucleus. In addition, dense punctate NADPH-diaphorase reaction product was found throughout the internal portion of median eminence. These data suggest the involvement of nitric oxide synthase producing neurons in homeostatic mechanisms controlling body fluid balance and the circulation.
authors.affiliation: Department of Physiology, University of Western Ontario, London, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Ciriello
authors.forename: S L
authors.initials: SL
authors.lastname: Hochstenbach
authors.forename: L
authors.initials: L
authors.lastname: Pastor Solano-Flores
mesh_terms: D000818:Animals; D003681:Dehydration / Q000201:enzymology*; D008058:Dihydrolipoamide Dehydrogenase / Q000378:metabolism*; D006651:Histocytochemistry; D008297:Male; D009474:Neurons / Q000201:enzymology* / Q000473:pathology; D016548:Prosencephalon / Q000201:enzymology* / Q000473:pathology / Q000503:physiopathology; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D008058:Dihydrolipoamide Dehydrogenase