title: [The effect of 2',5'-oligoadenylates on the expression of the cellular proto-oncogene c-myc during the development of Svec's leukemia in rats].
abstract: The effects of 2',5'-oligoadenilates (2,5A) on the survival of Wistar rats inoculated with Svec leukemia cells and the proliferation of tumoral cells were investigated. An agreement between the expression of c-myc protooncogene and inhibition of leukemic cell proliferation by 2,5A was found.
authors.forename: V I
authors.initials: VI
authors.lastname: Prima
authors.forename: A B
authors.initials: AB
authors.lastname: Kvitnitskaia
authors.forename: L G
authors.initials: LG
authors.lastname: Glushakova
authors.forename: P D
authors.initials: PD
authors.lastname: Tarasenko
authors.forename: A B
authors.initials: AB
authors.lastname: Stogniĭ
authors.forename: O F
authors.initials: OF
authors.lastname: Seniuk
authors.forename: O M
authors.initials: OM
authors.lastname: Platonov
mesh_terms: D000227:Adenine Nucleotides / Q000494:pharmacology*; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D005260:Female; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects* / Q000235:genetics; D007942:Leukemia, Experimental / Q000235:genetics* / Q000401:mortality / Q000473:pathology; D009368:Neoplasm Transplantation; D009843:Oligoribonucleotides / Q000494:pharmacology*; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology*; D016271:Proto-Oncogene Proteins c-myc / Q000187:drug effects* / Q000235:genetics; D012334:RNA, Neoplasm / Q000187:drug effects / Q000235:genetics; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D000227:Adenine Nucleotides; D009843:Oligoribonucleotides; D011500:Protein Synthesis Inhibitors; D016271:Proto-Oncogene Proteins c-myc; D012334:RNA, Neoplasm; C023505:2',5'-oligoadenylate
vernacular_title: Vliianie 2',5'-oligoadenilatov na ékspressiiu kletochnogo protoonkogena c-myc pri razvitii leĭkoza Shvetsa u krys.