title: [Telomerase].
abstract: Telomerase is expected to be a powerful tool for cancer diagnosis and cancer chemotherapeutics because of its selective expression exclusively in various cancer tissues at a high frequency (90%) in human somatic tissues. Some precancerous tissues also express telomerase at a high frequency. Normal somatic tissues are mostly telomerase negative. Cancer cells die after a loss of telomerase activity.
authors.affiliation: Department of Cellular and Molecular Biology, Hiroshima University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ide
authors.forename: H
authors.initials: H
authors.lastname: Tahara
mesh_terms: D017209:Apoptosis; D001483:Base Sequence; D006801:Humans; D008099:Liver / Q000201:enzymology; D008113:Liver Neoplasms / Q000201:enzymology; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000175:diagnosis / Q000201:enzymology / Q000473:pathology; D011230:Precancerous Conditions / Q000201:enzymology; D019098:Telomerase / Q000235:genetics / Q000378:metabolism*
chemical_list: D019098:Telomerase