Determining depth of invasion of advanced colorectal cancer using MRI short inversion time inversion recovery sequences.
To examine the usefulness of magnetic resonance imaging (MRI) in the preoperative determination of cancerous invasion, we examined 39 patients with advanced colorectal cancer with 0.5T MRI. We employed short inversion time inversion recovery (STIR) sequences, in addition to ordinary spin echo sequences for T1- and T2-weighted images. Preoperatively, the estimated depth of tumor invasion was classified into three grades according to MRI findings, and confirmed on the basis of surgical and histopathologic results. The depth of tumor invasion estimated preoperatively using STIR sequences corresponded well with the surgical and histopathologic results in 85% of the cases. In contrast, assessments based on T1-weighted images corresponded well in only 62% of the cases and T2-weighted images corresponded well in only 64%.
Masuko
E
E
Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan.
Homma
H
H
Mezawa
S
S
Matsuyama
T
T
Watanabe
N
N
Niitsu
Y
Y
D012809:Colon, Sigmoid / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011300:Preoperative Care; D012004:Rectal Neoplasms / Q000473:pathology*; D012007:Rectum / Q000473:pathology*; D012680:Sensitivity and Specificity; D012811:Sigmoid Neoplasms / Q000473:pathology*