The prospects for developing a vaccine against Staphylococcus aureus.
Staphylococcus aureus is an important bacterial pathogen with multiple virulence factors. The prevalence of antibiotic resistance among clinical isolates means that new vaccine strategies to prevent staphylococcal infections are needed. An ideal vaccine would induce antibodies to prevent bacterial adherence, promote opsonophagocytic killing by leukocytes and neutralize toxic secreted proteins.
Lee
J C
JC
Dept of Medicine, Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. jclee@warren.med.harvard.edu
D000818:Animals; D002240:Carbohydrate Sequence; D005544:Forecasting; D006801:Humans; D008969:Molecular Sequence Data; D013203:Staphylococcal Infections / Q000517:prevention & control*; D013209:Staphylococcal Vaccines / Q000276:immunology; D013211:Staphylococcus aureus / Q000276:immunology*
D013209:Staphylococcal Vaccines