title: Hemispherectomy for intractable seizures: a further modification and early experience.
abstract: Hemispherectomy is well recognized as an effective treatment for some types of intractable epilepsy, but the procedure is also known to be associated with significant late complications. A number of modifications to the original operation have been developed to try and minimize such late complications. These are reviewed and a further modification is described using a Zenoderm graft to isolate the hemispherectomy cavity from the remaining CSF pathways. We present our early experience with this new modification in seven patients with intractable epilepsy.
authors.affiliation: Walton Centre for Neurology and Neurosurgery, Liverpool, UK.
authors.forename: L T
authors.initials: LT
authors.lastname: Dunn
authors.forename: J B
authors.initials: JB
authors.lastname: Miles
authors.forename: P L
authors.initials: PL
authors.lastname: May
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology / Q000601:surgery*; D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology; D002675:Child, Preschool; D004827:Epilepsy / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D007839:Functional Laterality; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D019736:Prostheses and Implants
chemical_list: D000927:Anticonvulsants