Humoral immune response limits gene therapy in canine MPS I.
Shull
R
R
Lu
X
X
Dubé
I
I
Lutzko
C
C
Kruth
S
S
Abrams-Ogg
A
A
Kiem
H P
HP
Goehle
S
S
Schuening
F
F
Millan
C
C
Carter
R
R
D000818:Animals; D018076:DNA, Complementary / Q000235:genetics; D004285:Dogs / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D015316:Genetic Therapy; D005822:Genetic Vectors / Q000235:genetics; D007068:Iduronidase / Q000172:deficiency / Q000235:genetics / Q000276:immunology / Q000627:therapeutic use*; D007074:Immunoglobulin G / Q000096:biosynthesis*; D007518:Isoantibodies / Q000096:biosynthesis*; D008059:Mucopolysaccharidosis I / Q000276:immunology / Q000628:therapy*; D011993:Recombinant Fusion Proteins / Q000276:immunology / Q000627:therapeutic use; D012190:Retroviridae / Q000235:genetics
D018076:DNA, Complementary; D007074:Immunoglobulin G; D007518:Isoantibodies; D011993:Recombinant Fusion Proteins; D007068:Iduronidase