title: Trauma-induced severe acute pancreatitis in adults: conceptual review of pathophysiological events.
abstract: Trauma-induced severe acute pancreatitis in adults is used to demonstrate the complexity of a comprehensive conceptual pathophysiological review. The exemplar depicts a progression of pathological events evolving from pancreatic cell damage, as influenced by the stress response. Discussion of sequelae of the cardiovascular, respiratory, and renal systems is included, highlighting core concepts of inflammation, immunosuppression, fever, and impaired wound healing. Aspects of Neuman's Systems Model are introduced to guide the discussion. It is proposed that facilitating an in-depth conceptual understanding of pathology will enable nurses to improve "pattern" recognition, thereby enabling them to make quicker and more accurate assessments and diagnoses leading to treatment.
authors.forename: J F
authors.initials: JF
authors.lastname: Levy
authors.forename: J E
authors.initials: JE
authors.lastname: DeMartinis
mesh_terms: D000208:Acute Disease; D000328:Adult; D006801:Humans; D008297:Male; D016294:Models, Nursing; D009104:Multiple Trauma / Q000150:complications*; D010195:Pancreatitis / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology*; D013598:Systems Theory