title: Nucleotide sequence of exons 5 to 9 of the p53 tumour-suppressor gene of the horse (Equus caballus).
abstract: An evolutionary conserved 1.3 kb fragment corresponding to the horse p53 tumour suppressor gene was PCR amplified, cloned and the nucleotide sequence determined. The p53 fragment encoded exons 5 to 9 and the intervening introns. The nucleotide sequence and the predicted aminoacid sequence showed a high level of homology with human and donkey p53 sequences.
authors.affiliation: Department of Veterinary Clinical Studies, Glasgow University Veterinary School, Scotland, United Kingdom.
authors.forename: L
authors.initials: L
authors.lastname: Nasir
authors.forename: S W
authors.initials: SW
authors.lastname: Reid
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D017124:Conserved Sequence / Q000235:genetics; D016158:Genes, p53 / Q000235:genetics*; D006736:Horses / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012689:Sequence Homology, Nucleic Acid; D016159:Tumor Suppressor Protein p53 / Q000737:chemistry
chemical_list: D016159:Tumor Suppressor Protein p53