On the statistical distribution of amino acid residue in randomly synthesized peptides.
The probability of randomly synthesized peptides having an excess of a given residue Ri (nRi > N/2; N = size of the peptide) decreases strongly with peptide size. For a strong specific interaction of a Ri, rich peptide with a given sequence of a ribotide chain, peptides should be reasonably large. We discuss how a compromise can be achieved that may have had an important role on the origin of the genetic code.
De O Cavalcanti
A R
AR
Departamento de Química Fundamental, UFPE, Recife, Brasil.
Ferreira
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D000596:Amino Acids / Q000235:genetics*; D000926:Anticodon / Q000235:genetics; D005815:Genetic Code; D008957:Models, Genetic; D009843:Oligoribonucleotides / Q000235:genetics; D010455:Peptides / Q000235:genetics*; D013223:Statistics as Topic
D000596:Amino Acids; D000926:Anticodon; D009843:Oligoribonucleotides; D010455:Peptides