Anti-adhesion molecule and nitric oxide protection strategies in ischemic stroke.
In this review we focus on recent efforts designed to elucidate the role of inflammatory cells and nitric oxide in promoting cerebral ischemic cell damage, the mechanisms by which these events exacerbate ischemic cell damage, and the associated therapeutic interventions to protect tissue from ischemic injury.
Chopp
M
M
Neurology Department, Henry Ford Health Science Center, Detroit, MI 48202, USA.
Zhang
Z G
ZG
D002545:Brain Ischemia / Q000503:physiopathology*; D002561:Cerebrovascular Disorders / Q000503:physiopathology*; D006801:Humans; D007249:Inflammation / Q000503:physiopathology* / Q000628:therapy; D009569:Nitric Oxide / Q000378:metabolism*
D009569:Nitric Oxide