title: Hemostatic factors as triggers of cardiovascular events.
abstract: A growing body of evidence supports a role for hemostatic factors in triggering cardiovascular events. Fibrinogen has been identified as an independent cardiovascular risk factor that is as powerful a predictor as cholesterol. Factor VII, fibrinolytic potential, von Willebrand's factor, and platelet reactivity also have been linked to increased incidence of cardiovascular disease. Further characterization of these factors may lead to improved risk assessment and the development of new therapies for prevention.
authors.affiliation: Institute for Prevention of Cardiovascular Disease, Cardiovascular Division, Deaconess Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: G B
authors.initials: GB
authors.lastname: Rosito
authors.forename: G H
authors.initials: GH
authors.lastname: Tofler
mesh_terms: D001792:Blood Platelets / Q000502:physiology; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D002940:Circadian Rhythm; D003327:Coronary Disease / Q000097:blood; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis; D006487:Hemostasis; D006801:Humans; D012307:Risk Factors
chemical_list: D005340:Fibrinogen