[The relationship between cell membrane adrenoreceptor response and insulinemia in hypertension patients undergoing calcium antagonist treatment].
Dynamics of correlations between the absolute values and individual changes in adrenoception of erythrocytes and insulinemia was studied in 17 patients with hypertension (II stage) prior to and after 2-month treatment by calcium antagonists. Clear correlation is observed between the sensitivity of alpha- and beta- adrenoceptors and reduction of insulinemia after treatment with calcium antagonists (r = -0.77, p < 0.05). The effect of heterologous sensitization of cell membranes on metabolism in patients suffered with hypertonia after their treatment with calcium antagonists are discussed.
Dlusskaia
I G
IG
Striuk
R I
RI
Bobrovnitskiĭ
I P
IP
Petrova
T V
TV
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D002908:Chronic Disease; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000188:drug therapy*; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D015737:Nisoldipine / Q000627:therapeutic use*; D009568:Nitrendipine / Q000627:therapeutic use*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects* / Q000378:metabolism; D011943:Receptors, Adrenergic, beta / Q000187:drug effects* / Q000378:metabolism
D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D007328:Insulin; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D015737:Nisoldipine; D009568:Nitrendipine
Sviaz' mezhdu adrenoretseptsieĭ kletochnykh membran i insulinemieĭ u bol'nykh gipertonicheskoĭ bolezn'iu pri lechenii antagonistami kal'tsiia.