[The effect of new synthetic prostanoids on the indices of the blood coagulation system].
In the experiments on rabbits it was shown, that the administration of prostanoids IOS 3933 caused a reduction of ADP- and collagen induced platelet aggregation, platelet adhesion to collagen and elevation of t-PA level. This prostanoid prevented both a decrease in platelet count and reduction of AT III activity, but did not affect the protein C level during thromboplastin infusion.
Petrukhina
G N
GN
Makarov
V A
VA
Freĭmanis
Ia F
IaF
Lozha
E V
EV
Sirotenko
A V
AV
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001780:Blood Coagulation Tests / Q000706:statistics & numerical data; D011453:Prostaglandins / Q000494:pharmacology; D011465:Prostaglandins, Synthetic / Q000494:pharmacology*; D011817:Rabbits; D013997:Time Factors
D011453:Prostaglandins; D011465:Prostaglandins, Synthetic
Vliianie novykh sinteticheskikh prostanoidov na nekotorye pokazateli svertyvaiushcheĭ sistemy krovi.