title: Dicentric Y chromosome without evidence of mosaicism in an azoospermic male.
abstract: A phenotypically male of dicentric Y chromosome with no evidence of sex chromosomal mosaicism is reported. Staining of fluorescence in situ hybridization using Y chromosome centromere-specific DNA probe showed the presence of two bright fluorescent spots in Y chromosome. Testicular histology revealed maturation arrest at the stage of primary spermatocyte. It is suggested that structural anomaly of the Y chromosome is related to the disturbance of spermatogenesis.
authors.affiliation: Department of Urology, Yamagata University, School of Medicine, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Sasagawa
authors.forename: M
authors.initials: M
authors.lastname: Ishigooka
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: S
authors.initials: S
authors.lastname: Hayami
authors.forename: T
authors.initials: T
authors.lastname: Hashimoto
authors.forename: T
authors.initials: T
authors.lastname: Nakada
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000235:genetics*; D012729:Sex Chromosome Aberrations; D014998:Y Chromosome