Acute tubulointerstitial nephritis and uveitis with antineutrophil cytoplasmic antibody.
We report a case of acute tubulointerstitial nephritis and uveitis (TINU syndrome) in a 47-year-old woman who also was found to have antineutrophil cytoplasmic antibody. The patient developed severe acute renal failure that improved after a high dose (1 mg/kg/d) of corticosteroid therapy. The diagnosis of the disorder is discussed, as well as the finding of antineutrophil cytoplasmic antibody.
Simon
A H
AH
Division of Nephrology, Department of Internal Medicine, School of Medicine, University of Campinas (UNICAMP), Campinas, Brazil.
Alves-Filho
G
G
Ribeiro-Alves
M A
MA
D058186:Acute Kidney Injury / Q000188:drug therapy / Q000209:etiology; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000276:immunology*; D015415:Biomarkers / Q000032:analysis; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007684:Kidney Tubules / Q000473:pathology; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000150:complications / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D013577:Syndrome; D014606:Uveitis, Anterior / Q000150:complications / Q000188:drug therapy / Q000276:immunology*
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D015415:Biomarkers; D005938:Glucocorticoids; D011241:Prednisone