[Erythroid differentiation and specific protein synthesis by the leukemic cell line K-562 (under in-vivo cultivation conditions)].
Prolonged cultivation of K-562 human leukemic cells in plastagar diffusion chambers inserted into the peritoneal cavities of CBA mice indicated erythroid commitment and differentiation of cells. It was shown by the method of dot-hybridization with the use of oligonucleotide probe the presence of mRNA of globin in these cells.
Bil'ko
N M
NM
Korobov
V N
VN
Bebeshko
V G
VG
Starodub
N F
NF
D000005:Abdomen; D000818:Animals; D002454:Cell Differentiation; D003584:Cytological Techniques; D015194:Diffusion Chambers, Culture; D015672:Erythroid Precursor Cells / Q000166:cytology* / Q000378:metabolism*; D005914:Globins / Q000032:analysis / Q000096:biosynthesis*; D006801:Humans; D007938:Leukemia / Q000097:blood* / Q000473:pathology*; D051379:Mice; D008808:Mice, Inbred CBA; D012333:RNA, Messenger / Q000096:biosynthesis / Q000097:blood; D013997:Time Factors; D014407:Tumor Cells, Cultured
D012333:RNA, Messenger; D005914:Globins
Eritroidnaia differentsirovka i sintez spetsificheskogo proteina leĭkoznoĭ linieĭ kletok K-562 (v usloviiakh kul'tivirovaniia in vivo).