title: Sex differences and frequency content of the Frank lead signal-averaged ECG in a normal population.
abstract: To quantify the content of the signal-averaged electrocardiogram (ECG) in normal subjects, 100-beat signal-averaged Frank lead ECGs at a sampling rate of 1,000 Hz and with 16-bit resolution were recorded from 88 women and 102 men with a combined average age of 22 years. The QRS portion of each lead was digitally filtered in four bandwidths: 0-10, 10-60, 60-150, and 150-250 Hz. The root-mean-square voltage of each filtered signal was calculated as an absolute value and normalized as a percentage of the sum of the four filters. Women had significantly lower root-mean-square values in all filtered bands in Frank leads X and Z (P < .01). Normalized data, however, showed no sex difference (P > .05). Sex differences may affect quantitative measurement of the frequency content of the signal-averaged ECG.
authors.affiliation: Queens University, Kingston, Ontario, Canada.
authors.forename: R D
authors.initials: RD
authors.lastname: Seegobin
authors.forename: S A
authors.initials: SA
authors.lastname: Mohamed
mesh_terms: D000328:Adult; D003327:Coronary Disease / Q000175:diagnosis / Q000453:epidemiology; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D012307:Risk Factors; D012727:Sex Characteristics; D012737:Sex Factors; D012815:Signal Processing, Computer-Assisted