title: [Daily defined doses of parkinsonian drugs in Alcoi].
abstract: BACKGROUND
  Some authors have suggested that the use of DDD (defined daily doses) of L-dopa may be useful as an indicator of the frequency of Parkinson's disease.
  
  
  OBJECTIVE
  To determine the measurement for L-dopa and selegiline in Alcoi.
  
  
  METHODS
  We have obtained the intakes for L-dopa and selegiline between January and December, 1990 and we have calculated the DDD/1,000 inhab/day.
  
  
  RESULTS
  During the study period, we have found that the mean intakes were 18,000.969 mg and 53,800 mg for L-dopa and selegiline, respectively. And so, the L-dopa intake in Alcoi was 0.60 DDD/ 1,000 inh, and the selegiline intake was 0.21 DDD/1,000 inh.
  
  
  CONCLUSIONS
  Comparing the other data of the literature, specially in scandinavian countries, the obtained intake for L-dopa was low, and that could indicate that the frequency of the disease in Alcoi was lower.
authors.affiliation: Departmento de Medicina y Psiquiatria, Universidad de Alicante.
authors.forename: R
authors.initials: R
authors.lastname: Manzanares
authors.forename: J
authors.initials: J
authors.lastname: Matías-Guiu
authors.forename: R
authors.initials: R
authors.lastname: Provencio
authors.forename: R
authors.initials: R
authors.lastname: Falip
authors.forename: J
authors.initials: J
authors.lastname: López-Arlandis
authors.forename: R
authors.initials: R
authors.lastname: Martín
authors.forename: C
authors.initials: C
authors.lastname: Ruiz
mesh_terms: D000978:Antiparkinson Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004363:Drug Utilization; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage* / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000188:drug therapy*; D012642:Selegiline / Q000008:administration & dosage* / Q000627:therapeutic use*; D013030:Spain
chemical_list: D000978:Antiparkinson Agents; D012642:Selegiline; D007980:Levodopa
vernacular_title: Dosis diarias definidas de fármacos antiparkinsonianos en Alcoi.