Colonic ulceration associated with the systemic use of nonsteroidal antiinflammatory medication.
We report the first case of colonic ulceration precipitated by the intramuscular administration of ketorolac. This report suggests a role for the systemic effects of nonsteroidal antiinflammatory agents in the development of gastrointestinal ulceration.
Buchman
A L
AL
Division of Gastroenterology, Baylor College of Medicine, Houston, Texas 77030, USA.
Schwartz
M R
MR
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D003108:Colonic Diseases / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D020910:Ketorolac; D008171:Lung Diseases / Q000601:surgery; D010149:Postoperative Pain / Q000517:prevention & control; D014046:Tolmetin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D014456:Ulcer / Q000139:chemically induced / Q000473:pathology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D014046:Tolmetin; D020910:Ketorolac