title: Incidence of Vibrio cholerae O1 diarrhea in children at the onset of cholera epidemic in periurban Lima, Peru.
abstract: OBJECTIVE
  To determine the incidence of Vibrio cholerae O1-associated diarrhea in children during the onset of the 1991 cholera epidemic in Peru.
  
  
  METHODS
  Stool cultures were obtained from children (mean age, 26 months) participating in a prospective community-based study of diarrhea in a periurban community in Lima between February and May, 1991.
  
  
  RESULTS
  Of the 409 diarrheal episodes cultured V. cholerae O1 was isolated in 14 (3.4%) episodes. This represented an incidence of 0.11 episode per child year, higher than previously reported rates in children from endemic cholera areas. Most cases were mild; only 1 case required hospitalization.
  
  
  CONCLUSIONS
  Our study indicates that from the beginning of this epidemic, V. cholerae O1 caused diarrhea in children as well as adults and should therefore be considered as one of the possible pathogens when children from a cholera-affected area develop diarrhea.
authors.affiliation: Instituto de Investigación Nutricional, Lima, Peru.
authors.forename: A I
authors.initials: AI
authors.lastname: Gil
authors.forename: C F
authors.initials: CF
authors.lastname: Lanata
authors.forename: B
authors.initials: B
authors.lastname: Butron
authors.forename: A
authors.initials: A
authors.lastname: Gabilondo
authors.forename: M
authors.initials: M
authors.lastname: Molina
authors.forename: N
authors.initials: N
authors.lastname: Bravo
mesh_terms: D001424:Bacterial Infections / Q000175:diagnosis; D001431:Bacteriological Techniques; D002675:Child, Preschool; D002771:Cholera / Q000453:epidemiology* / Q000382:microbiology*; D003967:Diarrhea / Q000382:microbiology / Q000821:virology; D004196:Disease Outbreaks; D005243:Feces / Q000382:microbiology; D006801:Humans; D015994:Incidence; D007223:Infant; D019081:O Antigens / Q000276:immunology*; D010568:Peru; D012400:Rotavirus Infections / Q000175:diagnosis; D014505:Urban Population; D014734:Vibrio cholerae / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D019081:O Antigens