Signalling in lymphocyte development.
A number of important signal-transduction molecules that regulate lymphocyte maturation and proliferation have been identified. These advances provide a platform for studies on how different signalling events are integrated to generate the required number of lymphocytes with an appropriate antigen receptor repertoire.
Owen
M J
MJ
Imperial Cancer Research Fund, London, UK. owenm@icrf.icnet.uk
Venkitaraman
A R
AR
D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology* / Q000502:physiology*; D002454:Cell Differentiation / Q000276:immunology; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000276:immunology* / Q000502:physiology*; D006801:Humans; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000166:cytology* / Q000502:physiology*