[Study on treatment of infectious shock with recipe of liqi huoxue and kaibi gutuo].
Based on the pathogenesis of infectious shock which were stagnation of Qi, blood stasis, impairment of body resistance and trends to collapse, a series of new preparations of traditional Chinese Medicine was developed, Injection Kangjue Tongmai, Injection Yiqi Jiuyin and Injection Yiqi Huiyang, which could Liqi Huoxue and Kaibi Gutuo (regulate the flow of Qi, promote blood circulation, strengthen the body resistance and remit collapse), the result of 183 cases of infectious shock treated with them showed that the mortality was 4.37%, significantly lower than that of control group (23.0%). All three injections could rapidly elevate blood pressure and stabilize it for prolonged time, increase renal blood flow and lower blood viscosity. In animal experiment, the injections reduced lipid peroxide of vital organs, stabilized bio-membrane, protected the cell structure and maintained their normal functions.
Jin
M W
MW
Nanjing University of TCM.
Zhou
Z Y
ZY
Zhang
S W
SW
D000328:Adult; D000368:Aged; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001809:Blood Viscosity / Q000187:drug effects; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D011817:Rabbits; D012079:Renal Circulation / Q000187:drug effects; D012772:Shock, Septic / Q000175:diagnosis / Q000188:drug therapy*
D002317:Cardiovascular Agents; D004365:Drugs, Chinese Herbal; D008054:Lipid Peroxides