Cutaneous lymphangiectases associated with severe photoaging and topical corticosteroid application.
We report an elderly patient with lymphangiectases arising within skin affected by photoaging, steroid atrophy, and inflammation. Bullous lesions appeared in several sites following a year of topical corticosteroid applications for neurodermatitis. Light and electron microscopy showed that the bullae consisted of dilated lymphatic vessels within the dermis. There was also marked nodular elastosis and attenuation of dermal collagen. We suggest that this patient's lymphangiectases resulted from abnormal structure and function of the dermis due to photoaging and steroid atrophy.
Pena
J M
JM
Department of Pathology, University of Florida College of Medicine, Gainesville, USA.
Ford
M J
MJ
D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects*; D000368:Aged; D005260:Female; D006801:Humans; D008200:Lymphangiectasis / Q000139:chemically induced* / Q000473:pathology*; D015595:Skin Aging / Q000187:drug effects* / Q000473:pathology*; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology*
D000305:Adrenal Cortex Hormones