title: The haemolytic uraemic syndrome in patients with AIDS.
abstract: OBJECTIVE
  Thrombotic microangiopathies have been increasingly recognised in HIV infection. The contribution of haemolytic uraemic syndrome (HUS) has not received as much emphasis as other members of the thrombotic microangiopathies. We describe the clinical features and prognosis of HUS in a group of patients with AIDS.
  
  
  METHODS
  St Bartholomew's and The Middlesex Hospitals, London.
  
  
  METHODS
  Five HIV seropositive individuals with clinical and histological features consistent with HUS.
  
  
  METHODS
  Blood transfusion, fresh frozen plasma, haemodialysis, renal biopsy, autopsy.
  
  
  CONCLUSIONS
  HUS occurs in advanced HIV infection. Hypertension was a prominent clinical feature in HUS in this patient group. Measures to limit renovascular damage were unsuccessful and haemodialysis was usually needed to support renal function. The prognosis is poor, no patient achieved clinical remission and all died.
authors.affiliation: Department of Immunology, St Bartholomew's Hospital Medical College, London.
authors.forename: P
authors.initials: P
authors.lastname: Kelleher
authors.forename: A
authors.initials: A
authors.lastname: Severn
authors.forename: C
authors.initials: C
authors.lastname: Tomson
authors.forename: S
authors.initials: S
authors.lastname: Lucas
authors.forename: J
authors.initials: J
authors.lastname: Parkin
authors.forename: A
authors.initials: A
authors.lastname: Pinching
authors.forename: R
authors.initials: R
authors.lastname: Miller
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D017809:Fatal Outcome; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000209:etiology; D006801:Humans; D008297:Male; D011379:Prognosis