N-acetylcysteine inhibits germination of conidia and growth of Aspergillus spp. and Fusarium spp.
N-Acetylcysteine inhibited hyphal growth and germination of conidia of Aspergillus spp. and Fusarium spp. N-Acetylcysteine inhibited conidial germination as well as or better than L-cysteine. Cysteine-related compounds may provide a potential therapeutic strategy against agriculturally and medically important fungal pathogens.
De Lucca
A J
AJ
Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, Louisiana, USA.
Walsh
T J
TJ
Daigle
D J
DJ
D000111:Acetylcysteine / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects* / Q000502:physiology; D003545:Cysteine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005670:Fusarium / Q000187:drug effects* / Q000502:physiology; D008826:Microbial Sensitivity Tests; D013172:Spores, Fungal / Q000187:drug effects
D000935:Antifungal Agents; D003545:Cysteine; D000111:Acetylcysteine