[The effect of sodium nucleinate on the precursors of antigen-dependent suppressors following irradiation].
Sodium nucleinate was administered perorally to mice in the dose of 30 mg/kg. After the treatment the suppression activity of spleen cells decreased. The decrease was more pronounced in mice exposed to the doses of 0.5 and 1 Gy than in intact mice. The dose of 240 mg/kg did not affect suppression activity.
Surinov
B P
BP
Isaeva
V G
VG
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity / Q000187:drug effects* / Q000276:immunology / Q000528:radiation effects; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D005720:Gamma Rays; D007114:Immunization / Q000379:methods; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009696:Nucleic Acids / Q000494:pharmacology*; D011836:Radiation Tolerance / Q000187:drug effects; D013154:Spleen / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D013234:Stem Cells / Q000187:drug effects* / Q000276:immunology / Q000528:radiation effects; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects* / Q000276:immunology / Q000528:radiation effects; D013997:Time Factors
D000276:Adjuvants, Immunologic; D009696:Nucleic Acids; C013683:sodium nucleinate
Vliianie nukleinata natriia na predshestvenniki antigenzavisimykh supressorov posle oblucheniia.