Coexistence of multiple perifollicular fibromas and colonic polyp and cancer.
Perifollicular fibroma (PFF) is a rare cutaneous hamartoma that shows differentiation to the connective tissue sheath of the hair follicle. It may be solitary or multiple; the latter has been suggested to exhibit autosomal dominant inheritance and association with colonic polyposis. We report a 72-year-old Japanese female with multiple PFF on the face, possibly familial, who developed colon cancer in addition to colonic polyps.
Sasai
S
S
Department of Dermatology, Tohoku University School of Medicine, Sendal, Japan.
Takahashi
K
K
Tagami
H
H
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology; D000368:Aged; D003110:Colonic Neoplasms / Q000150:complications* / Q000473:pathology; D003111:Colonic Polyps / Q000150:complications / Q000473:pathology; D005260:Female; D006222:Hamartoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D009666:Nose; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology