Comparison of four human studies of perinatal exposure to methylmercury for use in risk assessment.
Newer data from human epidemiologic studies of methylmercury (MeHg) poisoning in which perinatal exposure occurred are available from four distinct populations. The results of an Iraqi grain-consuming population are compared to results from studies performed in fish-consuming groups in the Faroe Islands, the Seychelles Islands and in Peruvian fishing villages. A comparison of the results indicate that the Iraqi population does not represent a sensitive subpopulation within a perinatal group, but rather the relative lower threshold identified from this study was the results of confounders. Use of this benchmark dose for regulatory purposes may place a severe limitation upon fish consumption in the United States that is not fully supported by the scientific data.
Cicmanec
J L
JL
National Risk Management Research Laboratory, U.S. Environmental Protection Agency, Cincinnati, OH 45268, USA.
D003718:Denmark / Q000453:epidemiology; D004785:Environmental Pollutants / Q000506:poisoning*; D005506:Food Contamination; D006801:Humans; D007195:Indian Ocean Islands / Q000453:epidemiology; D007231:Infant, Newborn; D007493:Iraq / Q000453:epidemiology; D008767:Methylmercury Compounds / Q000506:poisoning*; D010568:Peru / Q000453:epidemiology; D018570:Risk Assessment
D004785:Environmental Pollutants; D008767:Methylmercury Compounds