title: The use of risperidone in treatment-resistant schizophrenia: two case reports.
abstract: The role of risperidone in the management of treatment-resistant schizophrenia remains unclear. We describe two patients with treatment-resistant schizophrenia characterized by unremitting delusions, thought disorder and self-neglect who had a sustained improvement in their symptoms soon after starting risperidone. Risperidone may be a suitable alternative to clozapine in some patients unresponsive to conventional antipsychotics.
authors.affiliation: University Department of Psychiatry, Royal Free Hospital, London, UK.
authors.forename: J P
authors.initials: JP
authors.lastname: Warner
authors.forename: J A
authors.initials: JA
authors.lastname: Gledhill
authors.forename: A
authors.initials: A
authors.lastname: Wakeling
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone