[The effect of benzine and formaldehyde on the prenatal development of rats with induced iron trace-element disorder].
Iron-deficiency anemia induced in the maternal organism markedly enhances embryotoxic and teratogenic effects of the studied pollutants: gasoline and formaldehyde. The prenatal effects of these drugs against the background of iron-deficiency state in pregnant females leads to development of the main feature of the tissue hypoxia, decompensated metabolic acidosis, in both the maternal organism and 20-day embryos.
Senichenkova
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Chebotar'
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D015082:2,2'-Dipyridyl; D000014:Abnormalities, Drug-Induced / Q000196:embryology / Q000209:etiology; D000473:Alkanes / Q000633:toxicity*; D018798:Anemia, Iron-Deficiency / Q000139:chemically induced / Q000196:embryology*; D000818:Animals; D004622:Embryo, Mammalian / Q000187:drug effects*; D005314:Embryonic and Fetal Development; D004785:Environmental Pollutants / Q000633:toxicity*; D005260:Female; D005557:Formaldehyde / Q000633:toxicity*; D007502:Iron Chelating Agents; D010578:Petroleum / Q000633:toxicity*; D011247:Pregnancy; D051381:Rats; D013997:Time Factors
D000473:Alkanes; D004785:Environmental Pollutants; D007502:Iron Chelating Agents; D010578:Petroleum; D005557:Formaldehyde; D015082:2,2'-Dipyridyl; C004544:naphtha
O vliianii benzina i formal'degida na prenatal'noe razvitie krys s indutsirovannym mikroélementozom zheleza.