title: [Differential characteristics of the temperature-sensitive period of the lawcp1 mutation on the basis of macrochaetae overexpression in Drosophila].
abstract: Temperature-sensitive periods (TSPs) of lawcpl mutations were studied via the frequencies of arising of extras macrochaetae for each macrochaetae type separately. TSPs for the formation of extras macrochaetae of original classes were unevenly distributed within larval instars II and III. It was found that macrochaetae of different types differed from one another in their temperature sensitivity. The TSP of development of macrochaetae belonging to new ectopic classes was multiphase, with the first phase at larval instar II, and the second phase, at the prepupal to early pupal stage. It is assumed that in Drosophila, the products of the lawc gene participate, along with other genes, in the development of the nervous system through regulation of ac-sc expression, both in proneural clusters and outside them.
authors.forename: O B
authors.initials: OB
authors.lastname: Simonova
authors.forename: S F
authors.initials: SF
authors.lastname: Petruk
authors.forename: L I
authors.initials: LI
authors.lastname: Korochkin
mesh_terms: D000483:Alleles; D000818:Animals; D004330:Drosophila / Q000033:anatomy & histology / Q000235:genetics* / Q000254:growth & development; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D017344:Genes, Insect; D005809:Genes, Regulator; D008465:Mechanoreceptors / Q000502:physiology; D009154:Mutation; D010507:Periodicity; D013696:Temperature
vernacular_title: Differentsial'naia kharkateristika temperaturochuvstvitel'nogo perioda mutatsii lawcpa po priznaku superékspressii makrokhet u drozofily.