title: Treatment of esophageal obstruction from mediastinal compressive tumor with covered, self-expanding metallic Z-stents.
abstract: BACKGROUND
  Mediastinal malignancies may involve the esophagus, leading to esophageal stenosis and dysphagia. Rigid and self-expanding esophageal stents have been used for effective palliation, but their use in extrinsic, compressive lesions is controversial.
  
  
  METHODS
  A retrospective review of self-expanding Gianturco-Rösch Z-stents that were successfully placed in 13 patients with malignant esophageal obstruction due to extrinsic lesions.
  
  
  RESULTS
  All patients had an improvement in dysphagia of at least two dysphagia grades. The mean dysphagia grade fell from 3.15 to 0.62. Mean survival was 2.2 months. Early (within 48 hours) procedure-related complications occurred in 4 of 13 patients and consisted of minor, transient chest pain that resolved within 6 hours (3 patients) and endoscopic stent dislodgment into the stomach (1 patient). Late complications (> 48 hours) occurred in 2 patients and consisted of a partial proximal stent migration and the development of a benign stricture proximal to the stent. There was no procedural or stent related mortality.
  
  
  CONCLUSIONS
  Esophageal obstruction and malignant dysphagia from extrinsic, compressive mediastinal malignancies can be effectively and safely palliated with self-expanding Gianturco- Rösch Z-stents.
authors.affiliation: Divisions of Gastroenterology, Oregon Health Sciences University, Portland 97201-3098, USA.
authors.forename: B T
authors.initials: BT
authors.lastname: De Gregorio
authors.forename: K
authors.initials: K
authors.lastname: Kinsman
authors.forename: R M
authors.initials: RM
authors.lastname: Katon
authors.forename: K
authors.initials: K
authors.lastname: Morrison
authors.forename: R R
authors.initials: RR
authors.lastname: Saxon
authors.forename: R E
authors.initials: RE
authors.lastname: Barton
authors.forename: F S
authors.initials: FS
authors.lastname: Keller
authors.forename: J
authors.initials: J
authors.lastname: Rösch
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003680:Deglutition Disorders / Q000209:etiology / Q000628:therapy; D004724:Endoscopy; D004940:Esophageal Stenosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications*; D008670:Metals; D008875:Middle Aged; D010166:Palliative Care; D011183:Postoperative Complications; D012189:Retrospective Studies; D015607:Stents; D015996:Survival Rate
chemical_list: D008670:Metals