[Protective effects of liu tea on CCl4 injured liver and its working mechanism].
Liu Tea can effectively prevent the elevation of SGPT and SGOT induced by CCl4 in mice, reduce MDA and elevate GSH and GSH-px levels. It also induces the anabolism of microsomal protein and hepatocyte microsomal cytochrome P-450. These results suggest that Liu Tea has protective effects on the liver, which may be related to the clearing of free radicals and inhibition of lipid peroxidation.
Wang
X
X
Faculty of Pharmacy, Lanzhou Medical College.
Yang
B
B
D000818:Animals; D002251:Carbon Tetrachloride; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D016166:Free Radical Scavengers / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D051379:Mice; D008862:Microsomes, Liver / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D008315:Malondialdehyde; D003577:Cytochrome P-450 Enzyme System; D002251:Carbon Tetrachloride; D005979:Glutathione Peroxidase; D005978:Glutathione