title: Ketorolac and propofol anesthesia in a patient taking chronic monoamine oxidase inhibitors.
abstract: There is continued controversy regarding the concurrent use of monoamine oxidase inhibitors (MAOIs) and opioids in anesthesia. MAOIs are being used in both psychiatry and also in the treatment of Parkinson's disease. The adverse interaction of meperidine with MAOIs is well described in the literature. Several other opioids used in anesthesia have been reported as potentially safe and also implicated in interaction with MAOIs. We present a case report using ketorolac as a nonopioid analgesic during a general anesthesia combined with midazolam and propofol in a successful approach in a patient continuing MAOI therapy.
authors.affiliation: Anesthesia Department, Stanford University Medical Center, CA 94305-5115, USA.
authors.forename: S P
authors.initials: SP
authors.lastname: Fischer
authors.forename: R
authors.initials: R
authors.lastname: Mantin
authors.forename: J G
authors.initials: JG
authors.lastname: Brock-Utne
mesh_terms: D018712:Analgesics, Non-Narcotic; D018686:Anesthetics, Intravenous; D004334:Drug Administration Schedule; D004347:Drug Interactions; D005260:Female; D006801:Humans; D020910:Ketorolac; D008875:Middle Aged; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology*; D015742:Propofol; D014046:Tolmetin / Q000031:analogs & derivatives*
chemical_list: D018712:Analgesics, Non-Narcotic; D018686:Anesthetics, Intravenous; D008996:Monoamine Oxidase Inhibitors; D014046:Tolmetin; D015742:Propofol; D020910:Ketorolac