Lung cancer with visual loss.
A 58-year-old man with primary large cell carcinoma of the lung presented with rapidly progressive, bilateral visual loss. The patient was alert and oriented, had no complaints of headache, and was found to have full ocular motility. The optic disks and fundi appeared normal. No visual pathway lesions or other CNS abnormalities were detected on neuro-imaging. The authors discuss their differential diagnosis, clinical diagnostic approach, and subsequent management of this unusual patient.
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Neuro-Ophthalmology Service, Wills Eye Hospital, Philadelphia, Pennsylvania, USA.
Augsburger
J J
JJ
Eagle
R C
RC
D018287:Carcinoma, Large Cell / Q000150:complications* / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D004596:Electroretinography; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000209:etiology; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D012164:Retinal Diseases / Q000209:etiology*; D014786:Vision Disorders / Q000209:etiology*