Histoplasmosis in the Muñiz Hospital of Buenos Aires.
Some epidemiological and immunological characteristics and the methodology of diagnosis of 44 cases of histoplasmosis (HP); 36 (27 males and 9 women) associated with AIDS (HP+AIDS) and 8 (7 males and 1 female) with other predisposing factors (HP+non AIDS), diagnosed in the Muñiz Hospital (MH) during 1994, were retrospectively studied. The median age (MA) of HP+AIDS patients was 28 years; 25.5 (22-40) in the women and 28.5 (20-42) in the men and 50 (22-58) years in the HP+non AIDS patients. The more frequent risk factors for HIV infection were intravenous drug addiction (55%) and homo/bisexuality (19%). The MA of these groups were 28 (20-39) and 41 (26-42) years, respectively. Tobaccoism was a predisposing factor in 83% of HP+non AIDS patients. The muco-cutaneous lesions scraping and blood-cultures established the initial diagnosis in 53% and 36% of HP+AIDS patients, respectively and the muco-cutaneous lesions biopsies in 75% of HP+non AIDS cases. At time of diagnosis, all HP+AIDS patients had < 200 while HP+non AIDS patients had > 200 CD4 + lymphocytes/microliters. Seventy two per cent of HP+AIDS patients were born in Buenos Aires (Bs As) city and 62% of HP+non AIDS patients were born in provinces of Argentina other than Bs As. At moment of diagnosis, 87.5% of HP+AIDS and 62.5% of HP+non AIDS patients lived in Bs As city and Bs As outskirts.
Bava
A J
AJ
Unidad Micología, Hospital de Infecciosas Francisco J. Muñiz, Buenos Aires, Argentina.
D015492:AIDS Serodiagnosis / Q000379:methods; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001118:Argentina / Q000453:epidemiology; D015153:Blotting, Western; D016516:CD4-CD8 Ratio; D002908:Chronic Disease; D005260:Female; D006660:Histoplasmosis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged