[The effect of alpha-glucosidase inhibitor on burning epigastralgia in dumping syndrome: a case report].
Dumping syndrome results from a rapid passage of carbohydrate in the small intestine after gastric surgery. A 50-year-old man developed the syndrome after surgery for peptic ulcer. He often complained of burning epigastralgia after meals. Various methods of treatment had only a limited effect. Acarbose, alpha-glucosidase inhibitor, suppresses the breakdown of carbohydrates in the small intestine and consequently reduced osmolarity. The patient had a dramatic improvement in the dumping syndrome including epigastralgia, diarrhea and perspiration with an administration of acarbose 50 mg. There was no intractable side effect. Preprandial administration of acarbose is a reasonable treatment in the case of dumping syndrome.
Mimura
M
M
Department of Anesthesiology, Takikawa Municipal Hospital, Japan.
Tsukakubo
T
T
Tsujiguchi
N
N
Hoshikawa
T
T
D020909:Acarbose; D004377:Dumping Syndrome / Q000188:drug therapy* / Q000209:etiology; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D005959:Glucosidases / Q000037:antagonists & inhibitors*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D010437:Peptic Ulcer / Q000601:surgery; D014312:Trisaccharides / Q000627:therapeutic use*
D004791:Enzyme Inhibitors; D014312:Trisaccharides; D005959:Glucosidases; D020909:Acarbose