Transcription: building an initiation machine.
Recent crystal and solution structures of components of the core transcription initiation complex that assembles at RNA polymerase II promoters reveal similarities to core histones and cyclin A.
Travers
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MRC Laboratory of Molecular Biology, Cambridge, UK.
D000818:Animals; D016213:Cyclins; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism; D006657:Histones / Q000737:chemistry; D006801:Humans; D008958:Models, Molecular; D011401:Promoter Regions, Genetic; D012319:RNA Polymerase II / Q000235:genetics*; D016385:TATA Box; D035181:TATA-Box Binding Protein; D035581:Transcription Factor TFIIB; D014157:Transcription Factors / Q000737:chemistry / Q000378:metabolism; D014158:Transcription, Genetic
D016213:Cyclins; D004268:DNA-Binding Proteins; D006657:Histones; D035181:TATA-Box Binding Protein; D035581:Transcription Factor TFIIB; D014157:Transcription Factors; D012319:RNA Polymerase II