[The effect of calcitrin and corticotropin on pulmonary surfactant and engorgement in rats during activation of the lateral hypothalamic area].
The level of phospholipids, cholesterol, lipase activity in bronchoalveolar washes and lungs' blood capacity were studied in rats. An action exerted upon the hypothalamus led to a decrease in the surfactant lipids and the blood capacity of lungs. Possible peptidergic mechanisms of this are discussed.
Lukina
S A
SA
Medical Institute, Izhevsk.
Kriuchkova
V I
VI
Timofeeva
M R
MR
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D002116:Calcitonin / Q000494:pharmacology*; D003035:Cobalt / Q000494:pharmacology; D006454:Hemoglobins / Q000032:analysis; D007026:Hypothalamic Area, Lateral / Q000187:drug effects* / Q000502:physiology; D008168:Lung / Q000737:chemistry; D008297:Male; D011652:Pulmonary Circulation / Q000187:drug effects* / Q000502:physiology; D011663:Pulmonary Surfactants / Q000187:drug effects* / Q000502:physiology; D051381:Rats
D006454:Hemoglobins; D011663:Pulmonary Surfactants; D003035:Cobalt; D000324:Adrenocorticotropic Hormone; D002116:Calcitonin
Vliianie kal'tsitrina i kortikotropina na surfaktant i krovenapolnenie legkikh krys pri aktivatsii lateral'nogo gipotalamicheskogo polia.