Necrobiotic xanthogranuloma with paraproteinemia.
Necrobiotic xanthogranuloma (NXG) is a rare skin disease mimicking necrobiosis lipoidica diabeticorum clinically and histologically. However, its association with paraproteinemia, and the evolution of hematologic malignancies in some cases, established NXG as a separate clinicopathologic entity. A typical case with indolent course is described.
Barzilai
A
A
Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel.
Trau
H
H
Shpiro
D
D
Yorav
S
S
D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003094:Collagen / Q000648:ultrastructure; D005260:Female; D005487:Foam Cells / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D009335:Necrobiosis Lipoidica / Q000175:diagnosis* / Q000473:pathology; D010265:Paraproteinemias / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology; D014973:Xanthomatosis / Q000175:diagnosis* / Q000473:pathology
D003094:Collagen