[Clinical study on effect of jinshisan on dissolution of extra-/ intrahepatic biliary stones].
In order to evaluate the role and mechanism of Jinshisan (JSS) in bile stone dissolution, 164 cases of extra-/ intrahepatic biliary stone patients were treated by a collaborated group, the therapeutic effect was observed by B-ultrasonography before and after treatment. Results showed: (1) Among the 164 cases, 26 cases (15.85%) were cured clinically; 73 (44.51%) were effective and 65 (39.63%) ineffective. (2) After treatment, in 84 patients of right hepatolith, the stone were diappeared in 10 cases, the size or number of stone decreased in 44 casess. In 34 patients with left hepatolith, the figure were 5 and 13 respectively. In 10 cases of choledocholith they were 10 and 10 respectively. While in 21 cases of multiple gallstone, only one case with stones of both sides disappeared, except 3 ineffective cases, others with stone decreased in size or number or disappeared unilaterally. (3) Gallston diappeared in 7 of 10 patients with size of stone <or= 5 mm, only 2 of them were ineffective. (4) The effect were better in those with treatment course > 6 months. (5) Analysis of bile showed that JSS could increase the amount of bile acid, decrease the bilirubin, mucous and bicarbonate radical in bile.
Pei
D K
DK
Institute of Integrated TCM-WM of Acute Abdomen, Dalian Medical University, Liaoning.
Feng
B A
BA
Guan
F L
FL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001646:Bile / Q000378:metabolism; D001647:Bile Acids and Salts / Q000378:metabolism; D017734:Bile Ducts, Extrahepatic; D001653:Bile Ducts, Intrahepatic; D001663:Bilirubin / Q000378:metabolism; D002756:Cholagogues and Choleretics / Q000627:therapeutic use*; D002769:Cholelithiasis / Q000097:blood / Q000188:drug therapy*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D042882:Gallstones / Q000097:blood / Q000188:drug therapy; D006801:Humans; D008297:Male; D008419:Materia Medica / Q000627:therapeutic use*; D008875:Middle Aged
D001647:Bile Acids and Salts; D002756:Cholagogues and Choleretics; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D008419:Materia Medica; D001663:Bilirubin