title: Draining cutaneous fistula associated with infection of hydroxyapatite orbital implant.
abstract: The implantation of an orbital hydroxyapatite implant was complicated by conjunctival dehiscence, cutaneous fistula formation, and infection with Staphylococcus aureus. Pathologic examination of the sphere 2 years after its implantation revealed reduction in the size of the implant, peripheral lamellar bone formation and central necrosis. This is the first report of this constellation of complications with hydroxyapatite spheres positioned in the orbit. The 2-year interval between implantation and removal of the sphere is the longest reported in a case with histopathologic analysis.
authors.affiliation: Department of Ophthalmology, Jules Stein Eye Institute UCLA School of Medicine, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Glasgow
authors.forename: D A
authors.initials: DA
authors.lastname: Weinberg
authors.forename: N
authors.initials: N
authors.lastname: Shorr
authors.forename: R A
authors.initials: RA
authors.lastname: Goldberg
mesh_terms: D000328:Adult; D000853:Anophthalmos / Q000601:surgery; D001672:Biocompatible Materials / Q000009:adverse effects*; D017577:Cutaneous Fistula / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D004322:Drainage; D017886:Durapatite / Q000009:adverse effects*; D015818:Eye Infections, Bacterial / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005141:Eyelid Diseases / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D009336:Necrosis / Q000209:etiology; D009915:Orbit / Q000473:pathology / Q000601:surgery*; D019736:Prostheses and Implants / Q000009:adverse effects* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013211:Staphylococcus aureus / Q000302:isolation & purification*
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite