Radiation-induced graft copolymer SBS-g-VP for biomaterial usage.
The grafting of 4-vinyl pyridine (VP) to styrene-butadienestyrene triblock copolymer (SBS) by radiation-induced graft copolymerization was studied. The cohesive properties such as cohesive energy (Ecoh), molar volume (V), solubility parameter (delta), molar molecular weight (WM), specific volume (Vg), and density (1/Vg) of SBS-g-VP graft copolymer were calculated according to the group contribution of Fedors. The morphology of SBS-g-VP was studied by optical polarizing microscopy. We also measured the glass transition temperature and the mechanical properties of SBS-g-VP graft copolymer. Contact angle and blood-clotting time experiments were also performed to evaluate the biocompatibility of SBS-g-VP. A second domain was found in the SBS-g-VP graft copolymer, which resulted in different properties between SBS-g-VP and SBS. The blood compatibility of SBS-g-VP as measured by the Lee-White clotting test was better than that of SBS and polystyrene.
Yang
J M
JM
Department of Chemical Engineering, Chang Gung College of Medicine and Technology, Taiwan, ROC.
Hsiue
G H
GH
D001672:Biocompatible Materials; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D002070:Butadienes; D002152:Calorimetry, Differential Scanning; D015921:Dental Implants; D004548:Elasticity; D005720:Gamma Rays; D006801:Humans; D008970:Molecular Weight; D011137:Polystyrenes / Q000528:radiation effects; D019736:Prostheses and Implants; D011725:Pyridines / Q000528:radiation effects; D013718:Tensile Strength
D001672:Biocompatible Materials; D002070:Butadienes; D015921:Dental Implants; D011137:Polystyrenes; D011725:Pyridines; C101916:SBS-g-VP copolymer; C101915:styrene-butadiene-styrene triblock copolymer; C029351:4-vinylpyridine