[The corrective properties of glycine in alcoholic intoxication in the fetal period of pregnancy].
Natural metabolite glycine administered per os to rats in the fetus period of pregnancy in a dose of 1 mg/kg was found to exert a corrective action with respect to the toxic effect of ethanol in the mother-fetus system. Glycine prevents loss in the body weight, normalizes functional state of the nervous system and metabolic disorders in the maternal organism, improve the redox processes in the lymphocytes changed under alcoholization, and protect the fetus both on the metabolic and microstructural levels.
Sheveleva
G A
GA
Filimonov
V G
VG
Uroshleva
L A
LA
Komissarova
I A
IA
Chirkova
E M
EM
Koppel'
M A
MA
Korneev
A A
AA
D000435:Alcoholic Intoxication / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D000818:Animals; D004353:Drug Evaluation, Preclinical; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000517:prevention & control; D005333:Fetus / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology; D005865:Gestational Age; D005998:Glycine / Q000627:therapeutic use*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D051381:Rats
D005998:Glycine
Korrigiruiushchie svoĭstva glitsina pri alkogol'noĭ intoksikatsii v plodnyĭ period beremennosti.