A case of bronchopleural fistula detected by monitoring plasma endothelin-1.
Levels of endothelin (ET)-1 peptide are transiently increased after major physical stress. While studying sequential changes in plasma ET-1 levels during various types of stress, we noticed that the level of plasma ET-1 began to rise 10 days post-operatively in one patient with lung cancer who had undergone a left lower lobectomy. 35 days postoperatively a bronchopleural fistula became clinically manifest. The case is presented and the use of plasma ET-1 as an indicator is discussed.
Yamashita
J
J
Department of Surgery II, Fukuoka University School of Medicine, Japan.
Kawahara
K
K
Shirakusa
T
T
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001983:Bronchial Fistula / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D016232:Endothelins / Q000097:blood*; D005260:Female; D005402:Fistula / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery; D008991:Monitoring, Physiologic; D010995:Pleural Diseases / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D011013:Pneumonectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000175:diagnosis*; D012680:Sensitivity and Specificity
D015415:Biomarkers; D016232:Endothelins