[The effect of different topical agents on pseudomonas infection of burn wound].
48 Wistar rats were scalded resulting in 15% TBSA full-thickness burn. Pseudomonas aeruginosa (10(9)/ml was inoculated to the wounds. The rats were divided into 6 groups. 5 different topical agents were separately applied to the wounds constituting 5 groups, and no drug was used in control group. Through observing the appearance of wound, the quantity of bacteria in the subeschar tissue and histo-pathological changes, we confirmed that AgSD-ZnSD-A cream was a satisfactory topical agent.
Guo
Z
Z
304th Hospital, Beijing.
Gao
W
W
He
L
L
D000818:Animals; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001381:Azepines / Q000627:therapeutic use; D002056:Burns / Q000150:complications; D004338:Drug Combinations; D005260:Female; D008297:Male; D011552:Pseudomonas Infections / Q000188:drug therapy*; D051381:Rats; D017208:Rats, Wistar; D012837:Silver Sulfadiazine / Q000627:therapeutic use*; D013411:Sulfadiazine / Q000627:therapeutic use; D014946:Wound Infection / Q000188:drug therapy*; D017967:Zinc Compounds / Q000627:therapeutic use
D000891:Anti-Infective Agents, Local; D001381:Azepines; D004338:Drug Combinations; D017967:Zinc Compounds; D013411:Sulfadiazine; C035229:laurocapram; D012837:Silver Sulfadiazine