title: (S)-(+)-2-(3'-carboxybicyclo[1.1.1]pentyl)-glycine, a structurally new group I metabotropic glutamate receptor antagonist.
authors.affiliation: Istituto di Chimica e Tecnologia del Farmaco, Università di Perugia, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Pellicciari
authors.forename: M
authors.initials: M
authors.lastname: Raimondo
authors.forename: M
authors.initials: M
authors.lastname: Marinozzi
authors.forename: B
authors.initials: B
authors.lastname: Natalini
authors.forename: G
authors.initials: G
authors.lastname: Costantino
authors.forename: C
authors.initials: C
authors.lastname: Thomsen
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism; D006224:Cricetinae; D004305:Dose-Response Relationship, Drug; D018698:Glutamic Acid / Q000008:administration & dosage / Q000494:pharmacology; D005998:Glycine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D007668:Kidney; D015394:Molecular Structure; D010716:Phosphatidylinositols / Q000378:metabolism; D051381:Rats; D018094:Receptors, Metabotropic Glutamate / Q000037:antagonists & inhibitors*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D001643:Bridged Bicyclo Compounds; D010716:Phosphatidylinositols; D018094:Receptors, Metabotropic Glutamate; C100726:UPF 596; D018698:Glutamic Acid; D005998:Glycine