Cryptococcosis: an unusual cause of endobronchial obstruction.
We report the case of a 43 year old male patient, with normal immune function, who presented with right middle and lower lobe collapse. At bronchoscopy, a white lobulated lesion was seen, completely obstructing the origin of bronchus intermedius. Bronchial washings and biopsy of the lesion demonstrated cryptococcal organisms. The patient responded clinically and radiologically to amphotericin B and flucytosine; however, repeat bronchoscopy revealed only partial resolution of the endobronchial lesion.
Mahida
P
P
Dept of Medicine, Hillbrow Hospital, Johannesburg, South Africa.
Morar
R
R
Goolam Mahomed
A
A
Song
E
E
Tissandie
J P
JP
Feldman
C
C
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001982:Bronchial Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000382:microbiology*; D001999:Bronchoscopy; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000382:microbiology*; D008297:Male; D011859:Radiography
D000935:Antifungal Agents; D000666:Amphotericin B; D005437:Flucytosine