[The efficacy of the immunomodulating action of Essentiale and the modified animal erythrocytes].
A relative order in reaction of immune system on antigenic irritant and its stability with respect to non-antigenic irritants is lowered to a greater extent in animals not able to swim, and in swimming animals it decreases to a smaller extent than in the case of administration of erythrocytes modified with essential (EME). After EME injections a phase of decreasing immunological reactivity with respect to T-dependent antigen; when essential is administered in animals the phase of immunosuppression is not observed. Essential normalized immune response to T-dependent antigen, if it is administered before physical load, combined with it, or after it. Injection of EME before the physical load increases its immunosuppressive effect.
Uteshev
B S
BS
Laskova
I L
IL
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects* / Q000276:immunology; D007111:Immunity, Cellular / Q000187:drug effects; D007114:Immunization; D010713:Phosphatidylcholines / Q000494:pharmacology*; D005082:Physical Exertion / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D013550:Swimming
D000276:Adjuvants, Immunologic; D010713:Phosphatidylcholines; C011246:essential 303 forte
Effektivnost' immunomoduliruiushchego deĭstviia essentsiale i modifitsirovannykh im éritrotsitov zhivotnykh.