title: [A case of carcinomatous peritonitis for which combination therapy of 5-FU, leucovorin and cisplatin was effective].
abstract: This case report describes a case of carcinomatous peritonitis which showed a good response to the combination therapy of 5-FU, leucovorin and cisplatin. A 55-year-old man was admitted with complaints of meteorism due to ascites fluid. Ascitic examination showed a high concentration of CEA and CA19-9, and adenocarcinoma cells. Laboratory and radiological examination did not reveal the origin of the carcinoma, and laparotomy suggested an appendiceal origin. The combination chemotherapy with 5-FU, leucovorin and cisplatin was conducted for a total of 11 courses for 2 years with good QOL until his death. This therapy was suggested to be useful for inoperable carcinomatous peritonitis.
authors.affiliation: Department of Internal Medicine, Kitasato Institute Hospital, Keio University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Okabe
authors.forename: N
authors.initials: N
authors.lastname: Kumagai
authors.forename: H
authors.initials: H
authors.lastname: Serizawa
authors.forename: N
authors.initials: N
authors.lastname: Iwabuchi
authors.forename: N
authors.initials: N
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Hamada
authors.forename: K
authors.initials: K
authors.lastname: Tsuchimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: S
authors.initials: S
authors.lastname: Morinaga
authors.forename: H
authors.initials: H
authors.lastname: Ishii
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001063:Appendiceal Neoplasms / Q000150:complications* / Q000188:drug therapy; D002945:Cisplatin / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology; D012074:Remission Induction
chemical_list: D002945:Cisplatin; D002955:Leucovorin; D005472:Fluorouracil