title: [Molecular biology of thyroid diseases].
abstract: Recent developments in molecular biology and the accessibility of techniques for clinical research have led to a better understanding of the background of common thyroid diseases. The cloning and sequencing of the thyroid stimulating hormone receptor, thyroid peroxidase and thyroglobulin, and the characterization of the protein-DNA interaction during thyroid hormone action, as well as the discovery of intracellular signal transduction pathways were the most important steps which resulted in new diagnostic and therapeutic approaches. New explanations of thyroid autoimmune processes are being investigated.
authors.affiliation: Debreceni Orvostudományi Egyetem, I. Belklinika.
authors.forename: E
authors.initials: E
authors.lastname: Nagy
authors.forename: E
authors.initials: E
authors.lastname: Mezösi
authors.forename: A
authors.initials: A
authors.lastname: Leövey
mesh_terms: D016147:Genes, Tumor Suppressor / Q000235:genetics; D006801:Humans; D008967:Molecular Biology; D011519:Proto-Oncogenes / Q000235:genetics; D011988:Receptors, Thyroid Hormone / Q000378:metabolism*; D011989:Receptors, Thyrotropin / Q000378:metabolism*; D013959:Thyroid Diseases / Q000276:immunology / Q000378:metabolism*; D013964:Thyroid Neoplasms / Q000276:immunology / Q000378:metabolism*; D013967:Thyroiditis, Autoimmune / Q000276:immunology
chemical_list: D011988:Receptors, Thyroid Hormone; D011989:Receptors, Thyrotropin
vernacular_title: A pajzsmirigy betegségeinek molekuláris biológiája.