title: [Alcohol dehydrogenase polymorphism and the genotypic adaptation of D. melanogaster to the action of selective factors].
abstract: Analysis of experimental populations of Drosophila has shown different selective value of S- and F-alleles of Adh locus under selection for delayed aging, resistance to elevated temperature and ethanol. Selection for delayed aging and resistance to hyperthermia was accompanied by an increase of Adhs frequency in populations and genotypic adaptation to ethanol- by an increase of AdhF frequency.
authors.forename: V N
authors.initials: VN
authors.lastname: Totskiĭ
authors.forename: N D
authors.initials: ND
authors.lastname: Khaustova
authors.forename: N A
authors.initials: NA
authors.lastname: Strel'tsova
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects / Q000235:genetics*; D000426:Alcohol Dehydrogenase / Q000032:analysis / Q000187:drug effects / Q000235:genetics*; D000483:Alleles; D000818:Animals; D002492:Central Nervous System Depressants / Q000494:pharmacology; D004331:Drosophila melanogaster; D004795:Enzyme Stability; D000431:Ethanol / Q000494:pharmacology; D005260:Female; D005838:Genotype; D006358:Hot Temperature; D008297:Male; D011110:Polymorphism, Genetic / Q000187:drug effects / Q000235:genetics*; D012098:Reproduction / Q000187:drug effects / Q000235:genetics; D012641:Selection, Genetic
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol; D000426:Alcohol Dehydrogenase
vernacular_title: Polimorfizm alkogol'degidrogenazy i genotipicheskaia adaptatsiia D. melanogaster k deĭstviiu selektivnykh faktorov.