title: Prevalence of anti-Taenia solium antibodies in sera from outpatients in an Andean region of Ecuador.
abstract: Sera from 9,254 individuals that presented at one of three outpatient clinics in Quito, Ecuador were assayed by indirect hemagglutination for the presence of antibodies reactive with antigens from Taenia solium cysts. Immunoblot analysis of 81 selected sera with IHA titers ranging from 0 to 1,028 showed that a titer of > or = 32 was suggestive of exposure to the parasite. Nine percent (9%) of the 9,254 patients had titers of 32 or greater. Of 3,503 sera from one clinic, which included sera from food handlers undergoing yearly physicals, 390 (11%) were positive. In addition, a correlation with age was seen in some, but not all, populations. In situations where age-related effects were noted, the highest incidence was seen in the youngest (0-20 years) and in the oldest (51-60 years) group. Thus, a resurgence of infection after a period of lower prevalence may be developing. Overall, this study shows that cysticercosis is relatively common and potentially a serious health problem in this region.
authors.affiliation: Instituto Nacional de Higiene y Medicina Tropical, Quito, Ecuador.
authors.forename: L
authors.initials: L
authors.lastname: Escalante
authors.forename: E C
authors.initials: EC
authors.lastname: Rowland
authors.forename: M R
authors.initials: MR
authors.lastname: Powell
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003551:Cysticercosis / Q000175:diagnosis*; D004484:Ecuador; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D013621:Taenia / Q000276:immunology*
chemical_list: D000909:Antibodies, Helminth