Dilantin hypersensitivity reaction.
Dilantin hypersensitivity syndrome is characterized by fever, rash, lymphadenopathy, facial edema, and hepatitis. Anemia, pharyngitis, diarrhea, and nephritis may also be present. The eruption may present as the classic erythematous follicular papules and pustules; or it may be pleomorphic, presenting as a morbilliform eruption, erythroderma, or toxic epidermal necrolysis. Early recognition and discontinuation of the medication are necessary to prevent a potentially fatal outcome. A case is presented and the literature reviewed.
Conger
L A
LA
Grabski
W J
WJ
D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D000927:Anticonvulsants / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D010672:Phenytoin / Q000009:adverse effects*
D000889:Anti-Arrhythmia Agents; D000927:Anticonvulsants; D010672:Phenytoin