title: [Genetics of sexual development and its disorders].
abstract: Different hypotheses for genetic control of sexual differentiation in humans are discussed. Information on structure and manifestation of genes determining development of internal and external male genitals is considered. The process of discovering the gene responsible for differentiation of the indifferent fetal gonad into testes is described. The etiological problems of sexual development disorders are considered on the basis of knowledge obtained by modern molecular and genetic methods.
authors.forename: G R
authors.initials: GR
authors.lastname: Osipova
mesh_terms: D012734:Disorders of Sex Development / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D005837:Genitalia, Male / Q000196:embryology; D006059:Gonadal Dysgenesis / Q000235:genetics; D006801:Humans; D008297:Male; D009154:Mutation; D013737:Testis / Q000196:embryology*; D014998:Y Chromosome
vernacular_title: Genetika razvitiia pola i ego narusheniia.