[Experimental study of sodium hyaluronate products on prevention of tendon adhesion].
In an experiment sodium hyaluronate product (SHP) was used to observe its effects on healing and preventing adhesion of rabbit muscle tendon. Several methods were used such as gross and histopathological observation, imaging analysis, anti-tension strength measurement. The results confirmed that SHP could reduce collagen contents in peri-tendon tissues and fibroblasts after surgery and decrease the formation of scars in peri-tendon tissues. Therefore, it is effective in preventing muscle tendon adhesion and improving slide function of muscle tendon. Besides, it does not hinder muscle tendon healing.
Xu
J
J
Department of Hand Surgery, Hua Shan Hospital, Shanghai Medical University.
Gu
Y
Y
Wang
H
H
D000818:Animals; D005260:Female; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D008297:Male; D009135:Muscular Diseases / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D011817:Rabbits; D013708:Tendon Injuries / Q000601:surgery*; D013710:Tendons / Q000601:surgery*; D000267:Tissue Adhesions / Q000517:prevention & control; D014945:Wound Healing / Q000187:drug effects
D006820:Hyaluronic Acid