[Epithelial-smooth muscle interaction in the regulation of the tonus of the airways in rats].
The rat trachea epithelium was found to affect a catecholamine-induced relaxation of the trachea smooth muscles, to release a relaxing factor, the producing of which depends on calcium and is regulated by calmoduline and proteinkinase C. The epithelium-induced relaxation seems to depend on the animal age.
Kapilevich
L V
LV
Siberian Medical University, Tomsk.
Baskakov
M B
MB
Medvedev
M A
MA
Kovalev
I V
IV
Kuskov
M V
MV
Petrov
E Iu
EIu
Timofeev
V Iu
VIu
D000375:Aging / Q000187:drug effects / Q000502:physiology; D000818:Animals; D001685:Biological Factors / Q000502:physiology; D000001:Calcimycin / Q000494:pharmacology; D004848:Epithelium / Q000187:drug effects / Q000502:physiology; D007476:Ionophores / Q000494:pharmacology; D008297:Male; D009126:Muscle Relaxation / Q000187:drug effects / Q000502:physiology; D009129:Muscle Tonus / Q000187:drug effects / Q000502:physiology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D014132:Trachea / Q000187:drug effects / Q000502:physiology
D001685:Biological Factors; D007476:Ionophores; C056250:epithelium-derived relaxant factor; D000001:Calcimycin
Epitelial'no-gladkomyshechnoe vzaimodeĭstvie v reguliatsii tonusa vozdukhonosnykh puteĭ krys.