title: [Chemotherapy of primary malignant brain tumors in adults].
abstract: Chemotherapy of primary malignant brain tumors (PMBT) is palliative, except for germinomas. It is used as adjuvant therapy or alone at recurrence. The chemosensitivity of PMBT differs among tumors of different histological types. The role of chemotherapy in the treatment strategy will be reviewed by tumor type (malignant astrocytic gliomas, anaplastic oligodendrogliomas and mixed gliomas, anaplastic ependymomas, medulloblastomas, germinomas, primary malignant cerebral lymphoma).
authors.affiliation: Clinique neurologique, Hôpital de la Salpêtrière, Paris.
authors.forename: K
authors.initials: K
authors.lastname: Hoang-Xuan
authors.forename: J Y
authors.initials: JY
authors.lastname: Delattre
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D004806:Ependymoma / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D018237:Germinoma / Q000188:drug therapy; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy; D008527:Medulloblastoma / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D009837:Oligodendroglioma / Q000188:drug therapy
vernacular_title: Chimiothérapie des tumeurs cérébrales malignes primitives de l'adulte.