[The correction of post-poisoning damages to the myocardium caused by carbophos].
Lipid peroxidation processes and levels of oxidative metabolism enzymes succinate and lactate dehydrogenases, as well as morphometric parameters of cardiomyocytes were studied in rats after exposure to malathion. The efficacy of oxymethacil and atropin correction of postintoxication injuries to the myocardium was assessed. The new drug oxymethacil is recommended to be included in the treatment protocols during the first 48 h after grave poisoning with malathion.
Myshkin
V A
VA
Bakhtizina
G Z
GZ
Bashkatov
S A
SA
Varlamova
T I
TI
Volkova
E S
ES
Enikeev
D A
DA
D000818:Animals; D000931:Antidotes / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D001285:Atropine / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D006321:Heart / Q000187:drug effects*; D007306:Insecticides / Q000506:poisoning*; D015227:Lipid Peroxidation / Q000187:drug effects; D008294:Malathion / Q000506:poisoning*; D009206:Myocardium / Q000378:metabolism; D011041:Poisoning / Q000188:drug therapy / Q000378:metabolism; D051381:Rats; D013997:Time Factors; D014498:Uracil / Q000031:analogs & derivatives / Q000627:therapeutic use
D000931:Antidotes; D000975:Antioxidants; D007306:Insecticides; D014498:Uracil; C003029:oxymethacil; D001285:Atropine; D008294:Malathion
Korrektsiia postintoksikatsionnykh povrezhdenii miokarda, vyzvannykh karbofosom.