title: Effect of stenting on graft vascularization after laryngotracheoplasty.
abstract: The management of pediatric airway stenosis has been an important topic of debate over the last few decades as prolonged intubation has become more common in the neonate. Although many surgical options are available, most would agree that use of expansion techniques (laryngotracheoplasty) with cartilaginous grafting is the procedure of choice for the severely stenotic airway. Controversy persists, however, regarding the role of stents. Advocates feel that stents serve to counteract scar contracture and support the newly constructed airway. In contrast, recent studies suggest that stenting results in impaired wound healing and an increased complication rate. The present study addresses the effect of stenting on the vascularization of cartilaginous grafts in an animal model. Thirty-six New Zealand white rabbits were evaluated after laryngotracheoplasty with autogenous cartilage grafting. Half of the animals were stented with a 2-cm section of an endotracheal tube that was secured just below the glottis. Three rabbits from each group were then painlessly sacrificed on days 4, 6, 8, 10, 14, and 21. Gross and histologic comparisons of the stented and nonstented specimens revealed similar wound healing. Measurements of graft vascularization were obtained with a computerized image measurement program, and a comparison was made regarding the rate of vascularization. There was a statistically significant increase in the rate of vascularization in the stented group (mean 73% versus 55% at day 10; p < .05). This analysis suggests that stenting does not inhibit early wound healing and specifically graft vascularization after laryngotracheoplasty.
authors.affiliation: Division of Otolaryngology-Head and Neck Surgery, University of North Carolina, Chapel Hill.
authors.forename: T C
authors.initials: TC
authors.lastname: Logan
authors.forename: D E
authors.initials: DE
authors.lastname: Henrich
authors.forename: W W
authors.initials: WW
authors.lastname: Shockley
mesh_terms: D000818:Animals; D007830:Larynx / Q000601:surgery*; D011817:Rabbits; D015607:Stents; D014132:Trachea / Q000601:surgery*; D014182:Transplantation, Autologous; D014945:Wound Healing