[The effect of the intratracheal administration of americium-241 on rat alveolar macrophages].
In experiments in rats it was found that 241Am transitory decreases the total cell number and alveolar macrophage's percentage in bronchoalveolar lavage fluid (BALF): increases the macrophages size and nuclear size; and increases acid phosphatase and lactate dehydrogenase activities in BALF. It was suggested that 241Am causes and activation in the alveolar macrophages which probably appears as one of factors provoking lung injuries.
Shopova
V
V
Sŭlovski
P
P
Dancheva
V
V
D000576:Americium / Q000008:administration & dosage*; D000818:Animals; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D002452:Cell Count / Q000528:radiation effects; D016676:Macrophages, Alveolar / Q000166:cytology / Q000528:radiation effects*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014132:Trachea
D000576:Americium
Vliianie intratrakheal'nogo vvedeniia ameritsiia-241 na al'veoliarnye makrofagi krys.