title: [Influence of thoracic spinal subarachnoid microinjection of noradrenaline on the effect of electroacupuncture].
abstract: Influence of thoracic spinal subarachnoid microinjection of noradrenaline (NA, 40 mg/20 microliters) on the effect of electroacupuncture (EA) at Neiguan (PC6) was observed in 40 rabbits anesthetized with urethan-chloralose. Results showed that: 1) EA of Neiguan (PC6) could significantly accelerate the recovery of ST-segment and T-wave of electrocardiogram induced by acute myocardial ischemia (AMI); 2). Subarachnoid microinjection of NA also could promote the recovery of ST, T and blood pressure of post-AMI; and 3) Subarachnoid microinjection of NA could strengthen the effect of EA of Neiguan (PC6) to promote the recovery of ST and T of Post-AMI. It suggests that alpha-receptors of intra-thoracic spinal cord participate in the action of EA of Neiguan (PC6) ameliorating AMI, and the upper thoracic segement is one of the links for connecting Neiguan and the heart.
authors.affiliation: Institute of Acupuncture & Moxibustion, China Academy of Traditional Chinese Medicine, Beijing.
authors.forename: J
authors.initials: J
authors.lastname: Liu
authors.forename: Z
authors.initials: Z
authors.lastname: Han
authors.forename: Q
authors.initials: Q
authors.lastname: Cao
authors.forename: S
authors.initials: S
authors.lastname: Chen
mesh_terms: D015670:Acupuncture Therapy; D000818:Animals; D015671:Electroacupuncture; D004562:Electrocardiography; D005260:Female; D007278:Injections, Spinal; D008297:Male; D008845:Microinjections; D017202:Myocardial Ischemia / Q000503:physiopathology*; D009638:Norepinephrine / Q000494:pharmacology*; D011817:Rabbits
chemical_list: D009638:Norepinephrine