Scavenger receptors in innate immunity.
Scavenger receptors are cell-surface proteins expressed by mammalian monocytes and macrophages and by invertebrate hemocytes, among other cell types. They exhibit distinctive ligand-binding properties, recognizing a wide range of ligands that include microbial surface constituents and intact microbes. The ligand-binding properties and expression patterns of these receptors suggest that they may function in one or more host-defense-related processes. Significant advances in scavenger receptor biology have recently been reported, including the identification of several new scavenger receptor genes.
Pearson
A M
AM
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA.
D000818:Animals; D017209:Apoptosis; D006434:Hemocytes / Q000737:chemistry* / Q000276:immunology; D007113:Immunity, Innate; D008264:Macrophages / Q000737:chemistry* / Q000276:immunology; D008958:Models, Molecular; D009000:Monocytes / Q000737:chemistry* / Q000276:immunology; D011956:Receptors, Cell Surface / Q000145:classification / Q000276:immunology / Q000502:physiology; D014945:Wound Healing
D011956:Receptors, Cell Surface