[Chemosensitivity of cultured meningiomas].
Meningioma is one of the popular benign brain tumors. However, the recurrence of this tumor is not infrequently encountered. In an attempt to establish the useful adjuvant therapy for the recurrent meningioma, in vitro chemosensitivity study for meningioma was conducted. Among various chemotherapeutic agents tested here, cisplatin showed highest cytotoxicity on cultured meningioma cells. In conclusion, cisplatin may be useful in adjuvant chemotherapy for the recurrent meningioma.
Tsuchida
T
T
Department of Neurosurgery, Kansai Medical University, Osaka, Japan.
Matsudaira
T
T
Yoshimura
K
K
Matsumoto
M
M
Shirayama
Y
Y
Numa
Y
Y
Kawamoto
K
K
D000970:Antineoplastic Agents / Q000494:pharmacology*; D002945:Cisplatin / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005047:Etoposide / Q000494:pharmacology; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology*; D008579:Meningioma / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D015376:Nimustine / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D015376:Nimustine; D005047:Etoposide; D002945:Cisplatin