title: Cryptococcosis: an unusual cause of endobronchial obstruction.
abstract: We report the case of a 43 year old male patient, with normal immune function, who presented with right middle and lower lobe collapse. At bronchoscopy, a white lobulated lesion was seen, completely obstructing the origin of bronchus intermedius. Bronchial washings and biopsy of the lesion demonstrated cryptococcal organisms. The patient responded clinically and radiologically to amphotericin B and flucytosine; however, repeat bronchoscopy revealed only partial resolution of the endobronchial lesion.
authors.affiliation: Dept of Medicine, Hillbrow Hospital, Johannesburg, South Africa.
authors.forename: P
authors.initials: P
authors.lastname: Mahida
authors.forename: R
authors.initials: R
authors.lastname: Morar
authors.forename: A
authors.initials: A
authors.lastname: Goolam Mahomed
authors.forename: E
authors.initials: E
authors.lastname: Song
authors.forename: J P
authors.initials: JP
authors.lastname: Tissandie
authors.forename: C
authors.initials: C
authors.lastname: Feldman
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001982:Bronchial Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000382:microbiology*; D001999:Bronchoscopy; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000382:microbiology*; D008297:Male; D011859:Radiography
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D005437:Flucytosine