title: ATSDR evaluation of health effects of chemicals. II. Mirex and chlordecone: health effects, toxicokinetics, human exposure, and environmental fate.
abstract: This document provides public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective of the toxicology of mirex and chlordecone. It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health. Additional substances will be profiled in a series of manuscripts to follow.
authors.affiliation: Agency for Toxic Substances and Disease Registry, U.S. Department of Health and Human Services, Atlanta, Georgia 30333, USA.
authors.forename: O
authors.initials: O
authors.lastname: Faroon
authors.forename: S
authors.initials: S
authors.lastname: Kueberuwa
authors.forename: L
authors.initials: L
authors.lastname: Smith
authors.forename: C
authors.initials: C
authors.lastname: DeRosa
mesh_terms: D000279:Administration, Cutaneous; D000280:Administration, Inhalation; D000284:Administration, Oral; D002273:Carcinogens / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D002319:Cardiovascular System / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects; D007631:Chlordecone / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D004064:Digestive System / Q000187:drug effects; D005314:Embryonic and Fetal Development / Q000187:drug effects; D004781:Environmental Exposure; D006801:Humans; D007107:Immune System / Q000187:drug effects; D007306:Insecticides / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D008917:Mirex / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D009154:Mutation / Q000187:drug effects / Q000235:genetics; D011634:Public Health; D012098:Reproduction / Q000187:drug effects
chemical_list: D002273:Carcinogens; D007306:Insecticides; D007631:Chlordecone; D008917:Mirex