title: Melanogenic factors: regulation of gene expression.
abstract: Melanogenesis is a multistep biochemical process resulting in the formation of melanin in pigment cells in the skin and the eye. Three melanogenic factors, tyrosinase, TRP1, and TRP2 participate in the pathway. Here, the regulation of gene expression of these melanocyte-specific markers is shortly reviewed.
authors.affiliation: Laboratory of Molecular Biology, Institute of Chest Diseases, Prague, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Vachtenheim
authors.forename: J
authors.initials: J
authors.lastname: Duchon
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D019746:Intramolecular Oxidoreductases; D007535:Isomerases / Q000235:genetics; D008543:Melanins / Q000096:biosynthesis* / Q000235:genetics*; D008562:Membrane Glycoproteins; D014442:Monophenol Monooxygenase / Q000235:genetics; D010088:Oxidoreductases; D011506:Proteins / Q000235:genetics; D014158:Transcription, Genetic
chemical_list: D008543:Melanins; D008562:Membrane Glycoproteins; D011506:Proteins; D010088:Oxidoreductases; C489799:TYRP1 protein, human; C064056:tyrosinase-related protein-1; D014442:Monophenol Monooxygenase; D007535:Isomerases; D019746:Intramolecular Oxidoreductases; C042501:dopachrome isomerase