Canine mandibular osteosarcoma: 51 cases (1980-1992).
Fifty-one dogs treated for mandibular osteosarcomas (OSs) were studied retrospectively. Treatments were partial mandibulectomy (n = 32); partial mandibulectomy and chemotherapy (n = 10); partial mandibulectomy and radiation therapy (n = 3); partial mandibulectomy, radiation therapy, and chemotherapy (n = 4); and radiation therapy alone (n = 2). The overall one-year survival rate was 59.3%. Dogs treated with surgery alone had a one-year survival rate of 71%, which is higher than the one-year survival rate for dogs with appendicular OSs treated with surgery alone (p of 0.001 or less; hazard ratio of 0.29). There was no apparent effect of various treatment modalities, nor institution where treatment was given, nor histological type. Histological score and, to a lesser extent, histological grade were predictive of survival outcome.
Straw
R C
RC
Department of Clinical Science, College of Veterinary Medicine, Colorado State University, Fort Collins 80523, USA.
Powers
B E
BE
Klausner
J
J
Henderson
R A
RA
Morrison
W B
WB
McCaw
D L
DL
Harvey
H J
HJ
Jacobs
R M
RM
Berg
R J
RJ
D000818:Animals; D003131:Combined Modality Therapy / Q000662:veterinary; D004283:Dog Diseases / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D004285:Dogs; D005260:Female; D008297:Male; D008339:Mandibular Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D012516:Osteosarcoma / Q000401:mortality / Q000556:secondary / Q000628:therapy / Q000662:veterinary*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome