Adult-onset foveomacular vitelliform dystrophy and indocyanine green videoangiography.
BACKGROUND
Adult-onset foveomacular vitelliform dystrophy (AOFVD) represents a heterogeneous group of disorders with different clinical, angiographic, and histopathological features. The most common form is characterized by a yellow, round to oval subretinal macular lesion with or without central pigmented spot.


METHODS
Eight patients affected by typical AOFVD underwent fluorescein angiography and indocyanine green videoangiography (ICGV).


RESULTS
Fluorescein angiography showed a central hypofluorescent spot surrounded by an irregular hyperfluorescent ring. ICGV demonstrated a foveal nonfluorescent spot, visible during the entire examination, and a hyperfluorescent area surrounding the central spot, which became evident soon after the beginning of the examination.


CONCLUSIONS
In light of previous histopathological studies, the central nonfluorescent spot may be interpreted as a masking effect of a pigment clump, whereas the hyper-fluorescent area may represent dye pooling or staining of the subretinal pigment epithelial material.
Battaglia Parodi
M
M
Eye Clinic, University of Trieste, Italy.
Iustulin
D
D
Russo
D
D
Ravalico
G
G
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005584:Fovea Centralis / Q000473:pathology*; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008266:Macula Lutea / Q000473:pathology*; D008268:Macular Degeneration / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged
D004396:Coloring Agents; D007208:Indocyanine Green