[The delta sleep-inducing peptide as a modulator of synaptic ultrastructure].
Results of morphometric study of ultrastructure of axosomatic and axospinous synapses of rat sensomotor neocortex after DSIP administration and in hypoxia showed that the peptide administration resulted in multidirectional changes in these type contacts in intact animals. This, apparently, is connected with their different functional specialization. Preliminary DSIP administration prevented changes, appearing in hypoxia in most of the parameters studied both in axosomatic and axospinous synapses.
Mendzheritskiĭ
A M
AM
Mikhaleva
I I
II
Matsionis
A E
AE
Pavilaĭtite
P E
PE
D000818:Animals; D001369:Axons / Q000187:drug effects / Q000648:ultrastructure; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D000860:Hypoxia / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000187:drug effects / Q000648:ultrastructure; D018377:Neurotransmitter Agents / Q000494:pharmacology*; D051381:Rats; D013569:Synapses / Q000187:drug effects* / Q000648:ultrastructure
D018377:Neurotransmitter Agents; D003701:Delta Sleep-Inducing Peptide
Del'ta-son indutsiruiushchiĭ peptid kak moduliator ul'trastruktury sinapsov.