[The functional status of the immunocompetent cells in animals at different times after the chronic action of irradiation and heat].
The proliferative response of thymic and splenic cells and the production of interleukin-1 and interleukin-2 by splenocytes were studied a day, three and six months after 25-fold separate and combination radiation (total dose 0.5 Gy) and heat (37 degrees C, 4h). The proliferative activity of lymphocytes of both organs was found to enhance a day after heating. No changes were found three months later. The proliferative activity of thymocytes in rats exposed to radiation and combination of the two factors was inhibited after six months. The production of interleukin-1 was lowered after irradiation.
Zhitkevich
T I
TI
Murzënok
P P
PP
D000818:Animals; D002455:Cell Division / Q000187:drug effects / Q000528:radiation effects; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D006358:Hot Temperature / Q000009:adverse effects*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000166:cytology / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology* / Q000528:radiation effects*; D013997:Time Factors
D004247:DNA
Funktsional'noe sostoianie immunokompetentnykh kletok u zhivotnykh v raznye sroki posle khronicheskogo deĭstviia oblucheniia i tepla.