title: Study of pancreatic secretion after subtotal gastrectomy followed by different methods of reconstruction.
abstract: To study the effect subtotal gastrectomies have on exocrine pancreatic function, 12 dogs were prepared with gastric and duodenal cannulas using a modified technique of Thomas. In our study protocol, we collected pancreatic juice by selective ductal cannulation after having applied two types of stimulation [tryptophan intraduodenally together with secretin intravenously (i.v.) and cholecystokinin i.v. together with secretin i.v.]. Our results did not show a significant increase in pancreatic juice after performing the gastrectomies. In both cases the concentration of bicarbonate decreased significantly in contrast to that in the control group. After Billroth I anastomosis, however, a significant decrease in the first periods of stimulation in relation to the gastrojejunostomy was appreciated. In the case of proteins, a loss of the dose/effect relation in these parameters was seen only after Billroth II anastomosis.
authors.affiliation: Department of Surgery, Faculty of Medicine, University of Alicante, Spain.
authors.forename: M T
authors.initials: MT
authors.lastname: Perez Vazquez
authors.forename: R C
authors.initials: RC
authors.lastname: Rico
authors.forename: J M
authors.initials: JM
authors.lastname: Heredia
authors.forename: F C
authors.initials: FC
authors.lastname: Polo
authors.forename: A C
authors.initials: AC
authors.lastname: Rosique
authors.forename: P S
authors.initials: PS
authors.lastname: Paz
authors.forename: R
authors.initials: R
authors.lastname: Martinez-Abarca
mesh_terms: D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D002766:Cholecystokinin / Q000494:pharmacology; D004285:Dogs; D005743:Gastrectomy; D010179:Pancreas / Q000378:metabolism*; D012633:Secretin / Q000494:pharmacology
chemical_list: D001639:Bicarbonates; D012633:Secretin; D002766:Cholecystokinin