title: [Historical evolution of the treatment of esophageal cancer at the Hospital A. C. Camargo, São Paulo, Brazil].
abstract: OBJECTIVE
  From 1947-1986 we reviewed a historical series of 1,900 cases of esophageal cancers registered at the A.C. Camargo Hospital, São Paulo, Brazil. Two hundred and thirty four cases were submitted to surgical resection. During these 4 decades the treatment philosophy of these tumors has changed.
  
  
  METHODS
  Five different historical groups were identified and the results are presented.
  
  
  RESULTS
  The first group (1947-60) consisted of 47 cases only submitted to surgical resection. The second group (1961-70) of 56 cases had pre and pos surgery radiotherapy in low doses and the reconstruction was made using subcutaneous colon. From 1971-75 the same approach was used except with high dose preoperative radiotherapy (31 cases). In the 4th group (1976-82) of 68 cases preoperative radiotherapy (high dose) and chemotherapy were used. In the last group (1983-86) composed of 32 cases the treatment was preoperative chemotherapy, surgical resection with gastric reconstruction followed with high doses radiotherapy in the surgical bed and chemotherapy. The only significant prognostic factors in the statistical analysis were tumor size and involvement peri-esophageal lymph nodes.
  
  
  CONCLUSIONS
  A five year survival from 3.7% to 9.0% was obtained through the use of the fifth group treatment planning.
authors.affiliation: Departamento de Cirurgia Torácica, Hospital do Serviço Social da Indústria, Barretos, SP.
authors.forename: A P
authors.initials: AP
authors.lastname: Mirra
authors.forename: F A
authors.initials: FA
authors.lastname: Justo
authors.forename: J E
authors.initials: JE
authors.lastname: Miziara
authors.forename: C A
authors.initials: CA
authors.lastname: Schneider
authors.forename: N
authors.initials: N
authors.lastname: Trippe
mesh_terms: D000328:Adult; D000368:Aged; D001938:Brazil; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000401:mortality / Q000628:therapy*; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000150:complications / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D016896:Treatment Outcome
vernacular_title: Evolução histórica do tratamento do câncer de esôfago no Hospital A.C. Camargo.