[An analysis of human marker chromosomes originating from chromosome 21 by using in situ hybridization].
Four cases of patients with additional marker chromosomes are described. The clinical, cytogenetic and molecular cytogenetic methods have been used for investigation. The identification of marker chromosomes was made by using in situ hybridization and the collection of chromosome-specific DNA probes. All marker chromosomes were determined as originated from chromosome 21 with break-points in the region between 21q11 and 21q22.
Zerova
T E
TE
Baronova
E V
EV
Gorovenko
N G
NG
Koblianskaia
G N
GN
Buzhievskaia
T I
TI
Vorsanova
S G
SG
Iurov
Iu B
IuB
D002869:Chromosome Aberrations / Q000235:genetics; D002871:Chromosome Banding; D002891:Chromosomes, Human, Pair 21 / Q000235:genetics*; D015342:DNA Probes; D004314:Down Syndrome / Q000235:genetics; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D010641:Phenotype
D015342:DNA Probes; D005819:Genetic Markers
Analiz markernykh khromosom cheloveka, proiskhodiashchikh ot khromosomy 21, s pomoshch'iu metoda gibridizatsii in situ.