Midazolam for intractable hiccup.
We describe two terminally ill cancer patients severely distressed by intractable hiccup. Commonly recommended treatments were ineffective. Intravenous midazolam 5-10 mg rapidly relieved the hiccup. Maintenance treatment comprised midazolam 40-120 mg/24 hr by continuous subcutaneous infusion.
Wilcock
A
A
Oxford Radcliffe Hospital NHS Trust, United Kingdom.
Twycross
R
R
D000368:Aged; D006606:Hiccup / Q000188:drug therapy*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D007680:Kidney Neoplasms / Q000150:complications / Q000473:pathology; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008874:Midazolam / Q000627:therapeutic use*; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000150:complications; D013727:Terminal Care
D006993:Hypnotics and Sedatives; D008874:Midazolam