title: The arteriovenous fistula for hemodialysis access: gold standard or archaic relic?
abstract: A five year retrospective review was undertaken to evaluate the patency rates of arteriovenous fistulae (AVF) in patients with end stage renal disease. From July 1989 through June 1994, 150 fistulae were created in the wrists of 144 patients. Thirty-four percent of the patients had diabetes mellitus. Patient death or irreparable fistulae were considered end points in the study. Patency rates were calculated by the Kaplan-Meier Actuarial Analysis. An analysis to assess the impact of the demographic characteristics, underlying renal disease, and effect of revisions on patency rates was calculated. The results demonstrate a high initial failure rate (less than 1 month) of 13 per cent in the entire cohort undergoing fistulae replacement. The 1 and 5-year patency rates were 56 per cent and 30 per cent, respectively. Diabetics had a significantly lower patency rate at 1 and 5 years (42% and 18%) respectively. Others, who had poor patency rates, include patients 70 years old or greater (40% patency at one year). The results suggest that the AVF should not be the first choice of access in elderly diabetics and that these patients would be better served with other modes of access, such as synthetic conduits or permanent indwelling venous catheters.
authors.affiliation: Department of Surgery, Indiana University Medical Center, Indianapolis, USA.
authors.forename: S B
authors.initials: SB
authors.lastname: Leapman
authors.forename: M
authors.initials: M
authors.lastname: Boyle
authors.forename: M D
authors.initials: MD
authors.lastname: Pescovitz
authors.forename: M L
authors.initials: ML
authors.lastname: Milgrom
authors.forename: R M
authors.initials: RM
authors.lastname: Jindal
authors.forename: R S
authors.initials: RS
authors.lastname: Filo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001166:Arteriovenous Shunt, Surgical; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods*; D012189:Retrospective Studies; D014654:Vascular Patency; D014953:Wrist