The use of hydrostatic pressure as a tool to study viruses and other macromolecular assemblages.
Recent studies on the effect of pressure on macromolecular assemblages have provided new information on protein-protein and protein-nucleic acid interactions. New findings have recently emerged on the use of hydrostatic pressure to assess intermediate states in the assembly pathways of viruses, multimeric proteins and protein-nucleic acid complexes, addressing many questions of macromolecular recognition.
Silva
J L
JL
Departamento de Bioquimica Médica, Universidade Federal do Rio de Janeiro, Brazil. jerson@server.bioqmed.ufrj.br
Foguel
D
D
Da Poian
A T
AT
Prevelige
P E
PE
D006874:Hydrostatic Pressure; D046911:Macromolecular Substances; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry*; D019065:Virus Assembly
D046911:Macromolecular Substances; D011506:Proteins