[Assisted reproduction vigilance].
Reports on assisted reproduction outcome show that some complications are more frequent than in the general population. These complications include preterm birth, low birthweight and perinatal mortality. Concern has been expressed that exposure to fertility drugs might be associated with the risk of ovarian cancer. Therefore it is important that new assisted reproduction technics (A.R.T.) be evaluated as rigorously and completely as every new drug before it is on the market. Evaluation of short term efficacy and safety of new A.R.Ts should be done using the methodology proposed for the evaluation of new drugs. To evaluate long term safety it is recommended that every A.R.T. center keeps on a standardized form informations on every attempt and its outcome. This information could be the basis for case control surveys looking at the long term consequences of A.R.T.
Bréart
G
G
INSERM-U.149, Paris.
de Mouzon
J
J
D016022:Case-Control Studies; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects; D006801:Humans; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D012099:Reproductive Techniques / Q000009:adverse effects*
D005300:Fertility Agents, Female
AMP vigilance.