title: [Cherubism: regression of the lesions and spontaneous bone regeneration].
abstract: Three cases of cherubism belonging to the same genealogical tree which had been followed up since the age of 7 years to adulthood are presented. These cases prove that, without treatment, the regression of the lesions and bone regeneration are real and not anecdotal. Nevertheless, following spontaneous bone regeneration, radiographically some radiolucent areas of low intensity and devoid of trabeculations, and/or areas of sclerotic bone do persist. In one case, cherubism was associated with peripheral giant cell granulomas localized in areas not affected by cherubism.
authors.affiliation: Clinique de Chirurgie Orale et Maxillo-Faciale, Université de Médecine et de Pharmacie, Iasi, Roumanie.
authors.forename: G C
authors.initials: GC
authors.lastname: Timosca
mesh_terms: D000328:Adult; D001861:Bone Regeneration; D002636:Cherubism / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000235:genetics / Q000473:pathology; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000235:genetics / Q000473:pathology / Q000503:physiopathology; D010026:Osteosclerosis / Q000235:genetics / Q000473:pathology; D012075:Remission, Spontaneous
vernacular_title: Le chérubisme : régression des lésions et régénération osseuse spontanée.