[Scavenging effects of daphnetin and its Cu, Zn complexes on superoxide radical].
The scavenging effects of daphnetin (D) and its Cu, Zn complexes on superoxide radical (O2-.) generated through the photooxidation of riboflavin were studied with human red blood cells (RBC) and RBC membrane as experimental material. The Cu ( II ) complex showed the highest activity. SOD, D and its Cu ( II ), Zn ( II ) complexes were found to have inhibitory effect on the production of lipid peroxide in the membrane, SOD being the best among them.
Hu
D
D
Chemistry Department of Shaanxi Normal University, Xi'an.
Fang
Y
Y
Cui
Y
Y
Sun
Z
Z
D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism; D016166:Free Radical Scavengers / Q000494:pharmacology*; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D010100:Oxygen / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism; D014468:Umbelliferones / Q000494:pharmacology*
D016166:Free Radical Scavengers; D005609:Free Radicals; D014468:Umbelliferones; D013481:Superoxides; D010100:Oxygen; C039952:daphnetin