title: [Cardiovascular effects of aqueous extracts of the leaves of Clusia coclensis (Guttiferae)].
abstract: Aqueous extracts of the leaves of Clusia coclensis, (Guttiferae) injected intravenously to 42 normal Sprague-Dawley rats and to 42 Spontaneous Hypertensive rats, in 7 different doses, induced a rapid and transitory decrease in blood pressure and heart frequency. The magnitude of blood pressure decrease was dose-dependent. The effect was statistically significant (p < or = 0.01), probably due to sympathetic stimuli.
authors.affiliation: Departamento de Fisiología, Universidad de Costa Rica.
authors.forename: M
authors.initials: M
authors.lastname: García González
authors.forename: O
authors.initials: O
authors.lastname: Morales Matamoros
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002317:Cardiovascular Agents / Q000494:pharmacology*; D005260:Female; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D011918:Rats, Inbred SHR; D017207:Rats, Sprague-Dawley
chemical_list: D002317:Cardiovascular Agents; D010936:Plant Extracts
vernacular_title: Efectos cardiovasculares del extracto acuoso de las hojas de Clusia coclensis (Guttiferae).