[The effect of antidepressants on the catecholamine content of the rat hypothalamus and adrenals].
Chronic administration of depressants of various classes in rats and a single administration of reserpine result in changes in catecholamine exchange in both hypothalamus and adrenal glands. Antidepressants prevent from a sharp decrease in level of hypothalamic dofamine, induced with reserpine. The importance of central dofaminergic mechanisms for specific effect of compounds is emphasized.
Arushanian
E B
EB
El'bek'ian
K S
KS
D000311:Adrenal Glands / Q000737:chemistry / Q000187:drug effects*; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001923:Brain Chemistry / Q000187:drug effects; D004298:Dopamine / Q000032:analysis*; D005470:Fluorometry; D006571:Heterocyclic Compounds / Q000494:pharmacology; D007031:Hypothalamus / Q000737:chemistry / Q000187:drug effects*; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D009638:Norepinephrine / Q000032:analysis*; D051381:Rats
D000928:Antidepressive Agents; D006571:Heterocyclic Compounds; D008996:Monoamine Oxidase Inhibitors; D004298:Dopamine; D009638:Norepinephrine
Vliianie antidepressantov na soderzhanie katekholaminov v gipotalamuse i nadpochechnikakh krys.