Neurotoxicity of Cyclosporine A in therapy of steroid resistant nephrotic syndrome in a 10-year old boy.
A 10-year old boy with steroid resistant nephrotic syndrome developed neurological symptoms during the combined therapy with Cyclosporine A, prednisone and ketonazole. These symptoms might be caused by Cyclosporine because the clinical course and laboratory data revealed neither inflammatory nor other causative factors.
Kwinta-Rybicka
J
J
Department of Pediatric Nephrology, Polish-American Childrens Hospital CMUJ, Kraków.
Ogarek
I
I
Sancewicz-Pach
K
K
D001927:Brain Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D002648:Child; D002699:Chlorambucil / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D011241:Prednisone / Q000008:administration & dosage; D012074:Remission Induction; D013256:Steroids / Q000494:pharmacology; D014057:Tomography, X-Ray Computed
D013256:Steroids; D002699:Chlorambucil; D016572:Cyclosporine; D003520:Cyclophosphamide; D011241:Prednisone; D008775:Methylprednisolone