Risperidone appears safe in patients with antipsychotic-induced blood dyscrasias.
Two cases are reported who developed blood dyscrasias, involving neutropenia and thrombocytopenia respectively, after treatment with phenothiazine and butyrophenone antipsychotics. A subsequent good therapeutic response was obtained with risperidone. It is suggested that risperidone may be considered as an alternative when blood dyscrasias occur with classic antipsychotics.
Mahmood
T
T
Wakari Hospital, Dunedin School of Medicine, University of Otago Medical School, New Zealand.
Silverstone
T
T
Spittle
B
B
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002090:Butyrophenones; D005260:Female; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000139:chemically induced* / Q000517:prevention & control; D010640:Phenothiazines; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000139:chemically induced* / Q000517:prevention & control; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy
D014150:Antipsychotic Agents; D002090:Butyrophenones; D010640:Phenothiazines; D018967:Risperidone