title: Cytochalasin W, a new 24-oxa[14]cytochalasan from Phoma exigua var. heteromorpha.
abstract: A further cytochalasin was isolated from liquid culture filtrates of Phoma exigua var. heteromorpha together with cytochalasins U and V and other well-known cytochalasins. The metabolite, named cytochalasin W, was characterized by spectroscopic and chemical methods as a new 24-oxa[14]cytochalasan, bearing a formyl group on the macrocyclic ring. Cytochalasin W showed toxic activity in the brine shrimp assay.
authors.affiliation: Dipartimento di Scienze Chimico-Agrarie, Università di Napoli Federico II, Portici, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Evidente
authors.forename: R
authors.initials: R
authors.lastname: Capasso
authors.forename: M
authors.initials: M
authors.lastname: Vurro
authors.forename: A
authors.initials: A
authors.lastname: Bottalico
mesh_terms: D000818:Animals; D001156:Artemia / Q000187:drug effects; D002855:Chromatography, Thin Layer; D003470:Culture Media; D003572:Cytochalasins / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D003904:Mitosporic Fungi / Q000378:metabolism*; D018515:Plant Leaves / Q000378:metabolism; D012015:Reference Standards; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013329:Structure-Activity Relationship
chemical_list: D003470:Culture Media; D003572:Cytochalasins; C101561:cytochalasin W