Alpha 2-adrenoceptors and I2 sites in the mammalian central nervous system.
The presence of alpha 2-adrenoceptors and I2 sites in the central nervous system is well established. This review provides a complete summary of this literature, commencing with the first description of alpha 2-adrenoceptors and I2 sites in the brain and covering in detail their subclassification, distribution, and function. Furthermore, it highlights some important differences between central alpha 2-adrenoceptors and I2 sites.
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Department of Physiology and Pharmacology, University of Strathclyde, Royal College, Glasgow, Scotland, UK.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D006801:Humans; D054755:Imidazoline Receptors; D018341:Receptors, Adrenergic, alpha-2 / Q000737:chemistry / Q000502:physiology*; D011955:Receptors, Drug / Q000737:chemistry* / Q000502:physiology*
D054755:Imidazoline Receptors; D018341:Receptors, Adrenergic, alpha-2; D011955:Receptors, Drug