[Molecular cloning of mutant loci obtained by microinjection of oncogenic viral DNA into polar plasma of early embryos of Drosophila melanogaster].
Mutations WRSV-1 and WRSV-4 obtained by microinjection of RSV cDNA into early embryos of Drosophila melanogaster were shown to be caused by the insertion of mobile elements jockey and B104(roo), respectively partial reversion of WRSV-lr arose due to the deletion of a 5'-region of mobile element jockey and of the adjacent region of the genomic DNA. It is concluded that genetic instability induced by oncoviral DNAs is based on the ability of these DNAs to induce transpositions of various mobile elements in the recipient genome.
Soldatov
A V
AV
Nabirochkin
S D
SD
D000818:Animals; D016764:Cell Polarity / Q000502:physiology; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004251:DNA Transposable Elements; D004279:DNA, Viral / Q000235:genetics*; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000502:physiology; D016678:Genome; D008845:Microinjections; D016254:Mutagenesis, Insertional; D009858:Oncogenic Viruses / Q000235:genetics*
D004251:DNA Transposable Elements; D004279:DNA, Viral
Molekuliarnoe klonirovanie mutantnykh lokusov, polychennykh mikroin"ektsieĭ DNK onkogennykh virusov v poliarnuiu plazmu rannikh émbrionov Drosophila melanogaster.