Mitochondrial disorders in neuro-ophthalmology.
The pathogenesis of mitochondrial disorders relevant to neuro-ophthalmology has been further clarified by identifying and correlating to disease manifestations the three primary pathogenic mutations of Leber's hereditary optic neuropathy, and by correlating genetic, biochemical, and histochemical abnormalities in the mitochondrial myopathies and encephalomyopathies.
Riordan-Eva
P
P
Department of Neuro-Ophthalmology, National Hospital for Neurology and Neurosurgery, London, UK.
Wood
N W
NW
D006801:Humans; D008928:Mitochondria / Q000473:pathology*; D017237:Mitochondrial Encephalomyopathies / Q000378:metabolism*; D017240:Mitochondrial Myopathies / Q000378:metabolism*; D015418:Optic Atrophies, Hereditary / Q000378:metabolism*