title: The impact of pre-donated autologous blood and intra-operative isovolaemic haemodilution on the outcome of transfusion in patients undergoing radical retropubic prostatectomy.
abstract: OBJECTIVE
  To assess the impact of pre-donated autologous blood and intra-operative isovolaemic haemodilution on the outcome of transfusions in patients undergoing radical retropubic prostatectomy.
  
  
  METHODS
  The charts and transfusion records of 192 consecutive patients undergoing radical retropubic prostatectomy were reviewed retrospectively.
  
  
  RESULTS
  Of 192 patients, 14% required homologous transfusions, the rate of which varied significantly depending upon blood availability (autologous, haemodilution or homologous) (P < 0.001): 66% of patients with only autologous blood available were transfused a mean of 1.96 units (range 1-6) of blood, of which 87% received autologous alone. 12% both autologous and homologous and 1% homologous blood only. Of the pre-donated autologous units, 44% were wasted.
  
  
  CONCLUSIONS
  Both the pre-donation of autologous blood and intra-operative isovolaemic haemodilution lower the risk of homologous blood transfusion. It is recommended that patients pre-donate 2 units of autologous blood and undergo intra-operative isovolaemic haemodilution before radical prostatectomy.
authors.affiliation: Department of Urology, Indiana University Medical Center, Indianapolis, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Nash
authors.forename: C G
authors.initials: CG
authors.lastname: Schrepferman
authors.forename: R G
authors.initials: RG
authors.lastname: Rowland
authors.forename: J
authors.initials: J
authors.lastname: Young
authors.forename: R S
authors.initials: RS
authors.lastname: Foster
authors.forename: R
authors.initials: R
authors.lastname: Birhle
authors.forename: J P
authors.initials: JP
authors.lastname: Donohue
mesh_terms: D001804:Blood Transfusion, Autologous / Q000379:methods*; D006438:Hemodilution / Q000379:methods*; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy / Q000379:methods*; D011469:Prostatic Diseases / Q000601:surgery; D012189:Retrospective Studies