title: Prevalence of gastroesophageal reflux in patients who develop pneumonia following percutaneous endoscopic gastrostomy: a 24-hour pH monitoring study.
abstract: Percutaneous endoscopic placement of feeding gastrostomies (PEG) was pioneered by Gauderer et. al. in 1980 [1]. Since then, it has become the preferred method of providing enteral nutritional support in children and adults because of advantages in morbidity and cost [2,3]. Pneumonia is a known sequel of this procedure, occurring at different rates, depending on the length of follow-up. Some series have shown an incidence of 10% at 30 days and others 56% at 11 months [4,5]. It does not appear that PEG feeding offers an advantage over the more traditional naso-enteric tube feeding methods in this respect. To study the prevalence of gastroesophageal reflux (GER) in PEG-fed patients, we quantitated GER by 24-hour intraesophageal pH monitoring in a group of patients who developed post-PEG pneumonia and compared it with a control group. Our study demonstrates an increased prevalence of GER in the pneumonia group compared with the control group. However, the exact contribution of this observed increased GER to the development of pneumonia needs to be determined.
authors.affiliation: Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, USA.
authors.forename: T P
authors.initials: TP
authors.lastname: Short
authors.forename: N R
authors.initials: NR
authors.lastname: Patel
authors.forename: E
authors.initials: E
authors.lastname: Thomas
mesh_terms: D000328:Adult; D000368:Aged; D003680:Deglutition Disorders / Q000628:therapy; D004724:Endoscopy; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000453:epidemiology*; D005774:Gastrostomy / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications* / Q000209:etiology*; D015995:Prevalence; D012307:Risk Factors