title: [The ecdysteroid fraction of the above-ground portion of Serratula coronata L. in the spontaneous E-rosette formation reaction and the agar migration test in vitro].
abstract: Reaction of E-rosette formation and agar migration test in vitro showed that small concentrations (7.5.10(-13) -7.5.10(-8) M) of phytosteroid ecdysterone (20-hydroxyecdysone) induce the activation of human lymphocytes. The effect of higher concentrations (7.5.10(-7) -7.5.10(-5) M) is less pronounced (two-phase effect).
authors.forename: D S
authors.initials: DS
authors.lastname: Trenin
authors.forename: V V
authors.initials: VV
authors.lastname: Volodin
authors.forename: Ia B
authors.initials: IaB
authors.lastname: Beĭkin
authors.forename: A B
authors.initials: AB
authors.lastname: Shlykova
mesh_terms: D000362:Agar; D001782:Blood Donors; D002465:Cell Movement / Q000187:drug effects / Q000276:immunology; D004305:Dose-Response Relationship, Drug; D026461:Ecdysteroids; D004441:Ecdysterone / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects* / Q000276:immunology; D006801:Humans; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D010936:Plant Extracts / Q000494:pharmacology*; D012397:Rosette Formation; D013256:Steroids / Q000494:pharmacology*
chemical_list: D026461:Ecdysteroids; D010936:Plant Extracts; D013256:Steroids; D004441:Ecdysterone; D000362:Agar
vernacular_title: Ekdisteroidnaia fraktsiia nadzemnoĭ chasti Serratula coronata L. v reaktsii spontannogo E-rozetkoobrazovaniia i agarmigratsionnom teste in vitro.