title: Adult-onset foveomacular vitelliform dystrophy and indocyanine green videoangiography.
abstract: BACKGROUND
  Adult-onset foveomacular vitelliform dystrophy (AOFVD) represents a heterogeneous group of disorders with different clinical, angiographic, and histopathological features. The most common form is characterized by a yellow, round to oval subretinal macular lesion with or without central pigmented spot.
  
  
  METHODS
  Eight patients affected by typical AOFVD underwent fluorescein angiography and indocyanine green videoangiography (ICGV).
  
  
  RESULTS
  Fluorescein angiography showed a central hypofluorescent spot surrounded by an irregular hyperfluorescent ring. ICGV demonstrated a foveal nonfluorescent spot, visible during the entire examination, and a hyperfluorescent area surrounding the central spot, which became evident soon after the beginning of the examination.
  
  
  CONCLUSIONS
  In light of previous histopathological studies, the central nonfluorescent spot may be interpreted as a masking effect of a pigment clump, whereas the hyper-fluorescent area may represent dye pooling or staining of the subretinal pigment epithelial material.
authors.affiliation: Eye Clinic, University of Trieste, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Battaglia Parodi
authors.forename: D
authors.initials: D
authors.lastname: Iustulin
authors.forename: D
authors.initials: D
authors.lastname: Russo
authors.forename: G
authors.initials: G
authors.lastname: Ravalico
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005584:Fovea Centralis / Q000473:pathology*; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008266:Macula Lutea / Q000473:pathology*; D008268:Macular Degeneration / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green