Serial in vitro transfer of hypersensitivity to cancer antigens by sensitised lymphocytes.
An account is given of the experimental serial in vitro transfer of antigen-specific delayed hypersensitivity to peripheral leukocytes, using antigen-specific Transfer factor solely as the initial source. Transfer was assessed with the leukocyte migration, lymphocyte locomotion and leukocyte adherence inhibition tests. The positive test results observed in all the experiments suggest that Transfer factor does not act as such, but triggers a reaction that expands the effect of hypersensitivity.
Fazio
M
M
Chair of Medical Oncology, University of Turin, Italy.
Carnevale-Schianca
F
F
Sabidussi
A
A
D000951:Antigens, Neoplasm / Q000276:immunology*; D006801:Humans; D006968:Hypersensitivity, Delayed; D007114:Immunization; D008214:Lymphocytes / Q000276:immunology*
D000951:Antigens, Neoplasm