[The clinical efficacy of taufon in the combined treatment of patients with chronic circulatory failure].
Monotherapeutic treatment of patients with chronic cardiac insufficiency of I and II functional class and patients of III FC with Russian drug taufon against the background of traditional therapy leads to improvement of objective and subjective indications of the disease. Taufon does not significantly affect central hemodynamics, but normalizes contractile myocardial function and increases tolerance to physical load. Taufon potentiates therapeutic efficacy of some drugs that makes it possible to reduce their doses. Pharmacokinetics is given. The efficacy and the absence of any toxic effects allow the authors to recommend the drug for treatment of patients with chronic cardiovascular as an drug additional to basic background therapy.
Zavolovskaia
L I
LI
Elizarova
E P
EP
Orlov
V A
VA
D000328:Adult; D000368:Aged; D002317:Cardiovascular Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D017079:Exercise Tolerance / Q000187:drug effects; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D013654:Taurine / Q000493:pharmacokinetics / Q000627:therapeutic use*; D013997:Time Factors
D002317:Cardiovascular Agents; D013654:Taurine
Klinicheskaia éffektivnost' taufona v kombinirovannom lechenii bol'nykh s khronicheskoĭ nedostatochnost'iu krovoobrashcheniia.