Lysis of erythrocytes by Trichomonas gallinae.
The hemolytic activity of five live isolates of Trichomonas gallinae was investigated. The isolates were subsequently tested against the erythrocytes of seven adult animal species. Each of the five isolates tested lysed all human blood groups, as well as rabbit, rat, chicken, horse, bovine, and sheep erythrocytes. No hemolysin released by the parasite could be detected. Our preliminary results suggest that the hemolytic activity is not due to the hemolysin release by T. gallinae or to a product of its metabolism. Pretreatment of live trichomonads with concanavalin A reduced levels of hemolysis by 40%.
De Carli
G A
GA
Departamento de Análises, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil.
da Silva
A C
AC
Wendorff
A
A
Rott
M
M
D000328:Adult; D000818:Animals; D010856:Columbidae / Q000469:parasitology*; D003208:Concanavalin A / Q000494:pharmacology; D004912:Erythrocytes; D006461:Hemolysis / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D014244:Trichomonas / Q000302:isolation & purification / Q000502:physiology*
D003208:Concanavalin A