[The effect of low doses of a synthetic analog of a quinoid radiotoxin on the viability of normal and gamma-irradiated animals].
The method for a production of synthetic quinoid radiotoxins in vitro has been developed and described. Synthetic quinoid radiotoxins like quinoid radiotoxins (qRT) which are being produced from irradiated tissues of the organisms have demonstrated high toxicity at relatively high qRT concentrations. However, when synthetic qRT is introduced into the organisms in ultra-small concentrations, one can observe the opposite action: the resistance of the organism increases and a number of essential functions are activated. Quinoid radiotoxins are assumed to take part in regulatory processes responsible for radiation hormesis.
Kopylov
V A
VA
Kuzin
A M
AM
Revin
A F
AF
Baranova
I A
IA
D000336:Aerosols; D000375:Aging / Q000187:drug effects; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005720:Gamma Rays; D051379:Mice; D014442:Monophenol Monooxygenase / Q000528:radiation effects; D011809:Quinones / Q000008:administration & dosage* / Q000138:chemical synthesis / Q000528:radiation effects; D011836:Radiation Tolerance / Q000187:drug effects; D012639:Seeds / Q000187:drug effects / Q000254:growth & development / Q000528:radiation effects; D011198:Solanum tuberosum / Q000201:enzymology; D013268:Stimulation, Chemical; D013997:Time Factors; D014908:Triticum / Q000187:drug effects / Q000254:growth & development / Q000528:radiation effects
D000336:Aerosols; D011809:Quinones; D014442:Monophenol Monooxygenase
Vliianie malykh doz sinteticheskogo analoga khinoidnogo radiotoksina na zhiznesposobnost' normal'nykh i gamma-obluchennykh zhivotnykh.