title: Locoregional immuno-chemotherapy transplenic and transtumoral in vivo immunostimulation.
abstract: The need for adjuvant therapies for treating the cancer patient has stimulated a great deal of research as well as controversy. Much of the current research is investigating chemotherapy and immunotherapy. One aspect of this research is directed at overcoming drug resistance by the target cells. This paper highlights some of the most recent advances in the fields of chemotherapy and immunotherapy, and discusses the effects of multi-drug resistance protein gene expression.
authors.affiliation: Department of Surgery, Athineon Hospital.
authors.forename: N J
authors.initials: NJ
authors.lastname: Lygidakis
authors.forename: K
authors.initials: K
authors.lastname: Stringaris
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000235:genetics*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000235:genetics / Q000276:immunology / Q000628:therapy; D003131:Combined Modality Therapy; D018432:Drug Resistance, Multiple / Q000235:genetics; D006801:Humans; D016219:Immunotherapy, Adoptive; D015979:Killer Cells, Lymphokine-Activated / Q000502:physiology; D008113:Liver Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy; D027425:ATP-Binding Cassette, Sub-Family C Proteins; D009363:Neoplasm Proteins; D010190:Pancreatic Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D019253:Proto-Oncogene Proteins c-bcl-2
chemical_list: D018528:ATP-Binding Cassette Transporters; D000970:Antineoplastic Agents; D027425:ATP-Binding Cassette, Sub-Family C Proteins; D009363:Neoplasm Proteins; D011505:Protein-Tyrosine Kinases; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2