title: Treatment of recurrent hypersomnia with methylcobalamin (vitamin B12): a case report.
abstract: A 32 year old male patient suffered from recurrent hypersomnia for 12 years was successfully treated with vitamin B12. Episodes of hypersomnia lasting a few days occurred repeatedly a few times each year. Furthermore, the frequency of episodes had increased during the last 2 years. During the administration of vitamin B12, the patient had no episodes of hypersomnia for 6 months. In addition, he did not have any episodes during a follow-up observation period of 17 months after cessation of the treatment. Thus, this case suggests that vitamin B12 may be effective for preventing recurrent hypersomnia.
authors.affiliation: Department of Psychiatry, Shiga University of Medical Science, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Yamada
mesh_terms: D000328:Adult; D002940:Circadian Rhythm / Q000187:drug effects; D006970:Disorders of Excessive Somnolence / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D012008:Recurrence; D012894:Sleep Stages / Q000187:drug effects; D014805:Vitamin B 12 / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: C019476:mecobalamin; D014805:Vitamin B 12