title: [Blood preservation in thoracic surgery: feasibility and limitations].
abstract: The transfusion of homologous blood carries risks associated with reactions to transfusion and the transmission of diseases. Minimizing surgery-related blood use is therefore of utmost importance. However, the application of blood-saving methods in surgery is restricted by a number of factors. Thoracic surgery poses particular problems in this regard due to the type of diseases treated, patients' general status and the use of neoadjuvant chemotherapy protocols. The aim of this study was to analyse the feasibility of a blood conservation program for thoracic surgery. A detailed analysis of blood-sparing techniques was carried out and the factors influencing blood consumption were evaluated in the preoperative, intraoperative and postoperative periods. Although pre-operative autologus blood donation is an extremely important factor, its effect is limited in thoracic surgery since only a few patients are suitable candidates for such a procedure. Our personal experience confirms the difficulty of applying a blood sparing program to thoracic surgery. Nevertheless the risks associated to transfusions, especially those related to the use of homologous blood, can be reduced by optimizing existing blood sparing techniques or developing new hemostatic agents.
authors.affiliation: Istituto Malattie dell'Apparato Cardiovascolare e Respiratorio, Università degli Studi, Milano.
authors.forename: P
authors.initials: P
authors.lastname: Zannini
authors.forename: A
authors.initials: A
authors.lastname: Carretta
authors.forename: G
authors.initials: G
authors.lastname: Melloni
authors.forename: G
authors.initials: G
authors.lastname: Chiesa
authors.forename: A
authors.initials: A
authors.lastname: Puglisi
authors.forename: A
authors.initials: A
authors.lastname: Grossi
mesh_terms: D001787:Blood Group Incompatibility; D016063:Blood Loss, Surgical; D001793:Blood Preservation; D001804:Blood Transfusion, Autologous; D006801:Humans; D013903:Thoracic Surgery
vernacular_title: Il risparmio di sangue in chirurgia toracica: attuabilità e limiti.