title: [Study of the usefulness of a kit containing imipenem/cilastatin powder with diluent for injection: convenience of use and preparation].
abstract: The usefulness of a newly developed imipenem/cilastatin powder-and-diluent kit packed in non-glass container was compared to that packed in commercially available glass vials. The imipenem/cilastatin powder-and-diluent kit container is made of a polyolefin bag with two chambers that contain imipenem/cilastatin powder and diluent (0.9% saline, 100 ml), respectively. The convenience of use of the kit and the time required for the preparation of the dosing solution were evaluated by nurses and pharmacists at the Kitasato University East Hospital. The newly developed kit received higher scores with regard to convenience of use and led to a 46 approximately 59% reduction in the time required for preparation as compared to the commercially available glass vials.
authors.affiliation: Department of Pharmacy, Kitasato University East Hospital, Kanagawa, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hirayama
authors.forename: M
authors.initials: M
authors.lastname: Kuroyama
authors.forename: S
authors.initials: S
authors.lastname: Shimda
mesh_terms: D015377:Cilastatin; D004349:Drug Packaging; D004359:Drug Therapy, Combination; D004526:Efficiency; D005898:Glass; D015378:Imipenem; D007267:Injections; D011090:Polyenes; D011208:Powders; D011480:Protease Inhibitors; D012965:Sodium Chloride; D013594:Syringes; D013845:Thienamycins
chemical_list: D011090:Polyenes; D011208:Powders; D011480:Protease Inhibitors; D013845:Thienamycins; D015377:Cilastatin; D012965:Sodium Chloride; D015378:Imipenem; C035051:PL 732