title: Cutaneous manifestation of leishmaniasis 40 years after exposure in a patient with chronic lymphocytic leukaemia.
abstract: Most individuals infected with the protozoan parasite Leishmania do not demonstrate overt disease, because of effective immune protection produced by T-cell mediated immunity. Acquired defects in T-cell responses may lead to emergence of leishmaniasis many years after exposure in endemic areas. We describe a case of a 75 year old man, who presented with a cutaneous manifestation of leishmaniasis 40 years after exposure, co-incident with the diagnosis of chronic lymphocytic leukaemia.
authors.affiliation: School of Life Sciences, Kingston University, Surrey, UK.
authors.forename: A P
authors.initials: AP
authors.lastname: Jewell
authors.forename: F J
authors.initials: FJ
authors.lastname: Giles
mesh_terms: D000368:Aged; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D007897:Leishmaniasis, Mucocutaneous / Q000276:immunology*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000276:immunology* / Q000469:parasitology; D008297:Male; D009894:Opportunistic Infections / Q000276:immunology* / Q000469:parasitology*