title: Antimicrobial susceptibilities of Lactococcus lactis and Lactococcus garvieae and a proposed method to discriminate between them.
abstract: The MICs of antimicrobial agents contained in the SCEPTOR Streptococcus MIC panels (Becton Dickinson Microbiology Systems) were determined for Lactococcus lactis, L. garvieae, and unknown Lactococcus species. Several isolates had reduced susceptibilities to many of the antimicrobial agents contained in the panel. For L. garvieae, the MICs of penicillin and, possibly, cephalothin were higher than for L. lactis, and unlike L. lactis, L. garvieae was resistant to clindamycin, indicating that knowledge of the Lactococcus species causing an infection might influence the choice of antimicrobial therapy. Susceptibility to clindamycin can also be used to differentiate between L. lactis and L. garvieae.
authors.affiliation: Streptococcus Reference Laboratory, Center for Infections Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Elliott
authors.forename: R R
authors.initials: RR
authors.lastname: Facklam
mesh_terms: D001431:Bacteriological Techniques; D002511:Cephalosporins / Q000494:pharmacology; D002512:Cephalothin / Q000494:pharmacology; D002981:Clindamycin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology; D006801:Humans; D017045:Lactococcus / Q000145:classification* / Q000187:drug effects* / Q000472:pathogenicity; D013294:Lactococcus lactis / Q000145:classification* / Q000187:drug effects* / Q000472:pathogenicity; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D013045:Species Specificity
chemical_list: D002511:Cephalosporins; D002981:Clindamycin; D002512:Cephalothin