Carotid body O2 chemoreception: respiratory and nonrespiratory aspects.
The respiratory and nonrespiratory hypotheses of O2 chemoreception in arterial chemoreceptors have been compared to provide a perspective that both mechanisms can potentially coexist. The nonrespiratory membrane mechanism operates at a relatively higher level of PO2 and that respiratory metabolic mechanisms at a lower level. The two mechanisms may overlap in the intermediate range of PO2.
Lahiri
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Department of Physiology, University of Pennsylvania, School of Medicine, Philadelphia 19104-6085, USA.
D000818:Animals; D002248:Carbon Monoxide / Q000097:blood; D002344:Carotid Body / Q000502:physiology* / Q000528:radiation effects; D003576:Electron Transport Complex IV / Q000502:physiology; D005930:Glossopharyngeal Nerve / Q000502:physiology; D006168:Guinea Pigs; D000860:Hypoxia / Q000503:physiopathology; D008027:Light; D008954:Models, Biological; D009130:Muscle, Smooth / Q000502:physiology / Q000528:radiation effects; D009419:Nerve Tissue Proteins / Q000502:physiology; D009475:Neurons, Afferent / Q000502:physiology; D009569:Nitric Oxide / Q000502:physiology; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D012119:Respiration
D009419:Nerve Tissue Proteins; D009569:Nitric Oxide; D002248:Carbon Monoxide; D003576:Electron Transport Complex IV; D010100:Oxygen