The collectins in innate immunity.
The collectins are proteins with collagen tails and globular lectin domains that appear to play an important role in mammalian first line host defense. Recent insights have clarified the structural basis of ligand recognition, the interactions of collectins with complement cascades, and the association with disease susceptibility.
Epstein
J
J
Department of Pediatrics, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Eichbaum
Q
Q
Sheriff
S
S
Ezekowitz
R A
RA
D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics / Q000276:immunology*; D002417:Cattle; D037222:Collectins; D003171:Complement Pathway, Classical; D004198:Disease Susceptibility / Q000208:ethnology / Q000276:immunology / Q000378:metabolism; D004285:Dogs; D006801:Humans; D007113:Immunity, Innate; D008024:Ligands; D037241:Mannose-Binding Lectins; D051379:Mice; D008958:Models, Molecular; D015394:Molecular Structure; D011817:Rabbits; D051381:Rats
D002352:Carrier Proteins; D037222:Collectins; D008024:Ligands; D037241:Mannose-Binding Lectins