title: Coexistence of choriocarcinoma and adenocarcinoma in the rectum: molecular aspects.
abstract: Choriocarcinoma, a malignant tumor of usually placental origin, in divided into two groups; the gestational and non-gestational types, the latter being rare. Non-gestational choriocarcinoma occurs in the lung, mediastinum, kidney, stomach, and small intestine, but rarely appears in the large intestine. We treated a 29-year-old woman with choriocarcinoma of the rectum with adenocarcinoma. Despite the rarity of the condition and the obscurity of the histogenesis, reports of similar cases and the occurrence of the tumors in the digestive tract suggest that the condition constitutes a clinical entity of a digestive tumor.
authors.affiliation: Department of Gastroenterology, Hyogo Medical Center for Adults, Akashi, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tokisue
authors.forename: K
authors.initials: K
authors.lastname: Yasutake
authors.forename: M
authors.initials: M
authors.lastname: Oya
authors.forename: H
authors.initials: H
authors.lastname: Nishisaki
authors.forename: T
authors.initials: T
authors.lastname: Nakashima
authors.forename: H
authors.initials: H
authors.lastname: Hasegawa
authors.forename: Y
authors.initials: Y
authors.lastname: Sakoda
authors.forename: T
authors.initials: T
authors.lastname: Kizaki
authors.forename: T
authors.initials: T
authors.lastname: Sashikata
authors.forename: R
authors.initials: R
authors.lastname: Morita
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D000328:Adult; D002822:Choriocarcinoma / Q000235:genetics* / Q000473:pathology; D003062:Codon / Q000235:genetics; D005260:Female; D016158:Genes, p53 / Q000235:genetics*; D011905:Genes, ras / Q000235:genetics*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D009154:Mutation; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D012004:Rectal Neoplasms / Q000235:genetics* / Q000473:pathology; D012007:Rectum / Q000473:pathology
chemical_list: D003062:Codon