title: Intracytoplasmic sperm injection: a treatment for extreme oligospermia.
abstract: OBJECTIVE
  We evaluated the efficacy of intracytoplasmic sperm injection in patients with extreme oligospermia.
  
  
  METHODS
  A total of 67 intracytoplasmic sperm injection cycles was attempted in 58 infertile couples in which the husbands had extreme oligospermia (less than 100,000 spermatozoa per ml. ejaculate).
  
  
  RESULTS
  Fertilization was achieved in 65 of 67 cycles. Mean fertilization rate per cycle was 66.4%. A total of 18 clinical pregnancies was obtained, for a pregnancy rate of 26.8% per started cycle. There were 4 miscarriages and 8 live births from 5 deliveries. Nine pregnancies are ongoing.
  
  
  CONCLUSIONS
  Intracytoplasmic sperm injection in patients with extreme oligospermia is associated with high fertilization rates and offers the chance of pregnancy to these otherwise intractably infertile couples.
authors.affiliation: Instituto Valenciano de Infertilidad, University of Valencia Medical School, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Gil-Salom
authors.forename: Y
authors.initials: Y
authors.lastname: Minguez
authors.forename: C
authors.initials: C
authors.lastname: Rubio
authors.forename: A
authors.initials: A
authors.lastname: Ruiz
authors.forename: J
authors.initials: J
authors.lastname: Remohi
authors.forename: A
authors.initials: A
authors.lastname: Pellicer
mesh_terms: D000328:Adult; D003593:Cytoplasm; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009845:Oligospermia; D009865:Oocytes; D011247:Pregnancy / Q000706:statistics & numerical data*; D013094:Spermatozoa