[Can permanent sinus arrhythmia in conscious dogs be suppressed with anesthesia?].
OBJECTIVE
Large prospective studies in dogs with healed myocardial infarction (MI) recently show a positive relation between heart rate variability (HRV) and sudden cardiac death.


METHODS
We have done similar experiments in dogs and we studied HRV, ECG and body surface potential maps (BSPM) in 26 normal mongrel dogs (10-15 kg) and 12 dogs with an experimental MI (ligation of LAD). A two-channel 8 hours lasting ECG recording was performed in all conscious dogs. The 2nd recording was done in Penthobarbital anaesthesia (30 mg/kg).


RESULTS
We have found sinus arrhythmia (SA) in all 26 conscious dogs. The anaesthesia suppressed the sinus arrhythmia and HRV via compensatory tachycardia and alterations in baroreflexes. The suppression of arrhythmia was also present in dogs with myocardial infarction.


CONCLUSIONS
It is suggested, that HRV and SA in dogs depend on conscious state and anaesthesia. On the basis of our results we can anticipate that the most important for HRV is the present status of the sympathetic nerve. We suggest, that our results are an important finding for experimental arrhythmology. (Fig. 4, Ref. 24.)
Bernadic
M
M
Ustav patologickej fyziológie, Lekárskej fakulty, Univerzity Komenského, Bratislave, Slovakia. bernadic@fmed.uniba.sk
Maasová
D
D
Sasváry
F
F
Holzerová
K
K
Hulín
I
I
D000758:Anesthesia; D000818:Animals; D001146:Arrhythmia, Sinus / Q000150:complications / Q000503:physiopathology*; D018780:Body Surface Potential Mapping; D004285:Dogs; D004562:Electrocardiography; D006339:Heart Rate; D009203:Myocardial Infarction / Q000150:complications
Môze byt permanentná sínusová arytmia u bdelých psov potlacená anestéziou?