title: Evaluation of the efficacy of oral cromolyn sodium or an oligoantigenic diet in children with atopic dermatitis: a multicenter study of 1085 patients.
abstract: One thousand eighty-five children with atopic dermatitis were enrolled in a multicenter study to evaluate the efficacy of 4 weeks of oral sodium cromoglycate or 4 weeks of a restricted diet. One thousand-eleven children (93%) concluded the study. At the end of the trial there was a significant improvement in skin lesions in the two groups: 61% of the patients in the sodium cromoglycate group and 69% in the restricted diet showed a significant improvement in atopic dermatitis. We concluded that, at least in our experimental design, both sodium cromoglycate and a restricted diet are equally effective in atopic dermatitis.
authors.affiliation: Ped. Dpt., La Sapienza University of Rome, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Businco
authors.forename: P
authors.initials: P
authors.lastname: Meglio
authors.forename: G
authors.initials: G
authors.lastname: Amato
authors.forename: V
authors.initials: V
authors.lastname: Balsamo
authors.forename: T
authors.initials: T
authors.lastname: Cainelli
authors.forename: P
authors.initials: P
authors.lastname: Cantone
authors.forename: M
authors.initials: M
authors.lastname: Castro
authors.forename: A
authors.initials: A
authors.lastname: Coletta
authors.forename: A
authors.initials: A
authors.lastname: Corrias
authors.forename: P L
authors.initials: PL
authors.lastname: Giorgi
authors.forename: I
authors.initials: I
authors.lastname: Grazioli
authors.forename: L
authors.initials: L
authors.lastname: Longo-Papadia
authors.forename: F
authors.initials: F
authors.lastname: Marcucci
authors.forename: M
authors.initials: M
authors.lastname: Masi
authors.forename: D
authors.initials: D
authors.lastname: Pavesio
authors.forename: S
authors.initials: S
authors.lastname: Scotta
authors.forename: S
authors.initials: S
authors.lastname: Seidenari
authors.forename: A
authors.initials: A
authors.lastname: Vierucci
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000941:Antigens / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004205:Cromolyn Sodium / Q000008:administration & dosage* / Q000627:therapeutic use*; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000276:immunology*; D004032:Diet; D005512:Food Hypersensitivity / Q000276:immunology* / Q000517:prevention & control; D006801:Humans; D007223:Infant
chemical_list: D000941:Antigens; D004205:Cromolyn Sodium