title: Increase in vasopressin binding sites in the human choroid plexus in Alzheimer's disease.
abstract: Vasopressin binding sites were determined in the choroid plexus of five Alzheimer's disease patients and five non-demented controls using the 125I-labelled linear V1a-antagonist. The Alzheimer's disease patients showed a twofold increase in the density of vasopressin binding sites, whereas the increase in the affinity constant Kd did not reach significance.
authors.affiliation: Graduate School Neurosciences Amsterdam, Netherlands Institute for Brain Research.
authors.forename: C
authors.initials: C
authors.lastname: Korting
authors.forename: E J
authors.initials: EJ
authors.lastname: van Zwieten
authors.forename: G J
authors.initials: GJ
authors.lastname: Boer
authors.forename: R
authors.initials: R
authors.lastname: Ravid
authors.forename: D F
authors.initials: DF
authors.lastname: Swaab
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000378:metabolism*; D000595:Amino Acid Sequence; D002831:Choroid Plexus / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D017483:Receptors, Vasopressin / Q000378:metabolism*
chemical_list: D017483:Receptors, Vasopressin