title: Reconstruction of the mitral annulus with porcine pericardium--report of a case with mitral annular disruption due to staphylococcal endocarditis.
abstract: A 60-year-old man was admitted to our hospital for investigation of dyspnea and disorientation with right hemiplegia. Echocardiography showed thickened mitral valve leaflets with vegetations and severe mitral regurgitation. Blood cultures grew Staphylococcus aureus. During the operation, perforation and destruction of the mitral valve leaflets and vegetations were confirmed. Debridement of the infected tissues resulted in segmental disruption of the posterior mitral fibrous annulus. Reconstruction of the mitral annulus with porcine pericardium treated with glutaraldehyde and mitral valve replacement were successful. The patient's postoperative course was complicated with metastatic cerebral and splenic abscesses. After splenectomy on the 8th postoperative day, he gradually recovered without major neurologic sequelae. We believe that reconstruction of the mitral valve annulus with pericardium, especially autologous pericardium, is reliable and useful for the treatment of patients with disruption of the mitral valve annulus.
authors.affiliation: Second Department of Surgery, Kurume University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Aoyagi
authors.forename: S
authors.initials: S
authors.lastname: Fukunaga
authors.forename: A
authors.initials: A
authors.lastname: Oryoji
authors.forename: K
authors.initials: K
authors.lastname: Kosuga
authors.forename: S
authors.initials: S
authors.lastname: Kanaya
authors.forename: M
authors.initials: M
authors.lastname: Ouchida
authors.forename: K
authors.initials: K
authors.lastname: Kuwano
authors.forename: T
authors.initials: T
authors.lastname: Sakamoto
mesh_terms: D000818:Animals; D001705:Bioprosthesis; D004697:Endocarditis, Bacterial / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D010496:Pericardium / Q000637:transplantation; D013203:Staphylococcal Infections / Q000150:complications*; D013552:Swine; D014183:Transplantation, Heterologous