Anti-GOR antibodies, HCV, liver disease and cryoglobulinemia.
OBJECTIVE
We investigated the presence of anti-GOR antibodies in patients with essential mixed cryoglobulinemia, since both autoimmune pathogenetic processes and a high prevalence of HCV infection are present in this syndrome.


METHODS
We compared these cases to patients with HCV-related chronic active hepatitis or alcoholism, and to ex-blood donors. A total of 60 patients with biopsy-proven chronic liver disease were studied.


RESULTS
HCV related markers, cryoglobulins, anti-GOR antibodies and ANA were detected in all of the groups.


CONCLUSIONS
Our data would appear to indicate that anti-GOR are related to the presence of HCV chronic hepatitis and not to cryoglobulinemia or chronic liver damage.
Saccardo
F
F
Ia Division of Medicine, Saronno Hospital, Italy.
Monti
G
G
Rinaldi
G
G
Pioltelli
P
P
Mosconi
L
L
Garelli
G
G
D003449:Cryoglobulinemia / Q000150:complications / Q000276:immunology* / Q000821:virology; D005260:Female; D016174:Hepacivirus / Q000276:immunology / Q000502:physiology; D018937:Hepatitis C Antibodies / Q000032:analysis*; D006521:Hepatitis, Chronic / Q000150:complications / Q000276:immunology* / Q000821:virology; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000150:complications / Q000276:immunology / Q000821:virology; D008297:Male; D014779:Virus Replication
D018937:Hepatitis C Antibodies