[One center's experience with fibrinolytic treatment in children].
Fifteen children treated with fibrinolytic agents are presented. The most frequent indication was thromboembolic disease (TED). Eleven patients received streptokinase, 5-urokinase and 3-tissue plasminogen activator. Concomitant heparin was administered to 9 patients with TED. Total resolution was achieved in 9 children, partial improvement in 5; 1 child died during treatment without any improvement. Bleeding complications were observed in 6 patients, 1 of them died due to haemorrhagic stroke. According to the literature and our own experience, we recommend fibrinolytic agents as the treatment of choice for severe TED also in children.
Jarmoliński
T
T
II Klinika Chorób Dzieci Instytutu Pediatrii Akademii Medycznej w Poznaniu.
Zachwieja
J
J
Kaczmarek-Kanold
M
M
Raysner
T
T
Stachowski
J
J
Bortkiewicz
E
E
Stefaniak
E
E
Warzywoda
M
M
Siwińska
A
A
Maciejewski
J
J
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013300:Streptokinase / Q000627:therapeutic use*; D013923:Thromboembolism / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014463:Ultrasonography; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging / Q000503:physiopathology
D005343:Fibrinolytic Agents; D013300:Streptokinase; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator
Leczenie fibrynolityczne u dzieci: doświadczenia własne.