A case of severe thrombocytopenia due to parvovirus B19 virus.
A 9-year-old girl admitted with generalized skin, mucosa, and genitourinary system bleeding had anemia and thrombocytopenia. Her bone marrow was normocellular. Parvovirus B19 IgM and IgG were positive. An absence of reticulocytopenia suggested that the virus affected only the megakaryocytic cell line and the anemia was due to generalized bleeding resulting from thrombocytopenia. Intravenous immunoglobulin treatment was instituted. On the tenth day of hospitalization the patient recovered from anemia and thrombocytopenia. IgM antibodies disappeared.
Yildirmak
Y
Y
Department of Pediatrics and Pediatric Hematology, Ankara University, Turkey.
Kemahli
S
S
Akar
N
N
Uysal
Z
Z
Cin
S
S
Arcasoy
A
A
D002648:Child; D016731:Erythema Infectiosum / Q000150:complications*; D005260:Female; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D016732:Parvovirus B19, Human; D013921:Thrombocytopenia / Q000821:virology*