Modification of tumor suppressor gene expression and induction of apoptosis in non-small cell lung cancer (NSCLC) with an adenovirus vector expressing wildtype p53 and cisplatin.
Roth
J A
JA
University of Texas M.D. Anderson Cancer Center, Department of Thoracic and Cardiovascular Surgery, Houston, USA.
D000256:Adenoviridae / Q000235:genetics*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D017209:Apoptosis / Q000235:genetics*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D002945:Cisplatin / Q000627:therapeutic use*; D002985:Clinical Protocols; D003131:Combined Modality Therapy; D016158:Genes, p53; D005822:Genetic Vectors; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D018579:Patient Selection
D000970:Antineoplastic Agents; D002945:Cisplatin