title: [Morbidity of Chagas disease in areas of Sertão da Paraiba and Caatinga do Piauí].
abstract: A clinical and electrocardiographic case control study was carried out with 186 pairs of persons with positive and negative serology for T. cruzi infection from the Sertão Paraíba and in 200 seropositive cases from the region of Caatinga in the State of Piauí, North-eastern Brazil. The predominant clinical manifestations in seropositive cases in both areas were: palpitations, dyspnea on effort, precordial pain, dysphagia, odynophagia, pyrosis and intestinal constipation. The EKG abnormalities rates suggestive of chronic chagasic cardiopathy were respectively in Paraíba and Piauí: AV block 3.8% and 2%, RBBB III 6.4% and 7%, RBBB III+ LAB 10.7% and 10.5%, and multifocal extrasystoles 2.7% and 3%. Xenodiagnosis in a sample of 54 seropositive individuals in the Sert-ao of Para-iba and in 120 in the Caatinga of Piauí was revealed 13% and 34% positive; PCR tests in a sample of 47 seropositives in Paraíba and 101 in Piauí revealed positives in 44.6% and 59.5% respectively. Blood culture in LIT media of 101 seropositive cases from the Caatinga of Piauí was positive for T. cruzi in 25.7%. A triatomine survey carried out in a sample of 132 domiciles and peridomiciles in the Sertão of Paraíba and in a sample of 159 in the Caatinga of Piauí showed the following results: In Paraíba, 16 specimens of T. brasiliensis, not infected with T. cruzi, were captured. In Piauí, 750 triatomines were captured, of these 625 were examined: 49 were T. pseudomaculata, not infected with T. cruzi (19 in peridomiciles and 30 in the domiciles), and 576 were T. brasiliensis (371 in the domiciles and 205 in the peridomiciles) and of this latter specie 32 (5.5%) were infected with T. cruzi (31 in the domiciles and one in the peridomicile).
authors.affiliation: Departamento de Medicina Tropical do Instituto Oswaldo Cruz (FIOCRUZ), Rio de Janeiro.
authors.forename: J R
authors.initials: JR
authors.lastname: Coura
authors.forename: J
authors.initials: J
authors.lastname: Borges-Pereira
authors.forename: F I
authors.initials: FI
authors.lastname: Alves Filho
authors.forename: J A
authors.initials: JA
authors.lastname: de Castro
authors.forename: R V
authors.initials: RV
authors.lastname: da Cunha
authors.forename: W
authors.initials: W
authors.lastname: Costa
authors.forename: A C
authors.initials: AC
authors.lastname: Junqueira
mesh_terms: D001938:Brazil / Q000453:epidemiology; D014355:Chagas Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D009017:Morbidity; D015995:Prevalence
vernacular_title: Morbidade da doença de Chagas em áreas do Sertão da Paraíba e da Caatinga do Piauí.