Immune functions of immunoglobulin Y isolated from egg yolk of hens immunized with various infectious bacteria.
We studied the immune functions of IgY obtained from hens immunized with a mixture of formalin-treated pathogenic bacteria. The IgY inhibited the growth of Pseudomonas aeruginosa, the production of Staphylococcus aureus enterotoxin-A, and adhesion of Salmonella enteritidis to cultured human intestinal cells (Caco 2). The results indicated that IgY specific for plural bacteria has effects useful toward prevention of bacterial diseases.
Sugita-Konishi
Y
Y
Department of Biomedical Food Research, National Institute of Health, Tokyo, Japan.
Shibata
K
K
Yun
S S
SS
Hara-Kudo
Y
Y
Yamaguchi
K
K
Kumagai
S
S
D000818:Animals; D001422:Bacterial Adhesion / Q000276:immunology; D001424:Bacterial Infections / Q000517:prevention & control; D002478:Cells, Cultured; D002645:Chickens; D004530:Egg Yolk / Q000276:immunology*; D004768:Enterotoxins / Q000096:biosynthesis; D005260:Female; D006801:Humans; D007114:Immunization; D007136:Immunoglobulins / Q000276:immunology* / Q000302:isolation & purification / Q000378:metabolism; D007422:Intestines / Q000166:cytology / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000254:growth & development / Q000276:immunology*; D012477:Salmonella enteritidis / Q000254:growth & development / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology* / Q000378:metabolism
D004768:Enterotoxins; C016512:IgY; D007136:Immunoglobulins; C026066:enterotoxin A, Staphylococcal