title: Ethical, social and counselling issues in hereditary cancer susceptibility.
abstract: Genetic testing for hereditary susceptibility to disease is new. Much has been learned from experience with Huntington's disease and other non-malignant conditions. There are some differences in the case of predisposition testing for cancer: there is often the perception that cancer is preventable and sometimes curable, in contrast to other hereditary conditions. Testing raises many issues new to the medical community and to the public as well. There is great concern that the explosive technology be used responsibly, so that the potential benefits of genetic knowledge are not eclipsed by the risks to autonomy, privacy and justice. Practical concerns about insurability and discrimination may inhibit some at risk individuals from taking advantage of this powerful technology. There has been considerable effort already in the UK, Europe and the USA at the research and social levels to create protection for individuals found to carry genetic susceptibility to disease.
authors.affiliation: Dana-Farber Cancer Institute, Boston, MA 02115-6084, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Garber
authors.forename: A F
authors.initials: AF
authors.lastname: Patenaude
mesh_terms: D001675:Bioethics; D002648:Child; D003219:Confidentiality; D004198:Disease Susceptibility; D004651:Employment; D004995:Ethics, Professional; D005190:Family; D005817:Genetic Counseling; D006801:Humans; D007348:Insurance, Health; D007352:Insurance, Life; D007398:Interpersonal Relations; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000517:prevention & control