title: A new magnetically suspended centrifugal pump: in vitro and preliminary in vivo assessment.
abstract: To overcome problems derived from the shaft within the conventional centrifugal pump, we have been developing a new centrifugal pump, namely a magnetically suspended centrifugal pump (MSCP), which has no shaft and operates as a noncontacting and bearingless pump. The impeller is suspended magnetically between the magnetic bearing and the driving motor. Hemolysis tests were performed in comparison with the Biopump (BP80, BioMedicus). The index of hemolysis (IH) was significantly lower in the MSCP than in the Biopump. In addition, a smaller gap in the MSCP induced lower hemolysis. In preliminary studies using mongrel dogs, the layer of thrombus adherent to the impeller was observed in a few hours, which impaired the pumping efficiency. However, by using an impeller coated with silicone, no aggregations of platelets or fibrin on the impeller were observed in 24 h of continuous pumping. In conclusion, the MSCP had a gentler influence on blood cells than the Biopump, and the impeller coated with silicone may contribute to the long-term pumping of the MSCP.
authors.affiliation: Department of Cardiovascular Surgery, Kyoto University, Japan.
authors.forename: C H
authors.initials: CH
authors.lastname: Park
authors.forename: K
authors.initials: K
authors.lastname: Nishimura
authors.forename: T
authors.initials: T
authors.lastname: Akamatsu
authors.forename: T
authors.initials: T
authors.lastname: Tsukiya
authors.forename: K
authors.initials: K
authors.lastname: Matsuda
authors.forename: T
authors.initials: T
authors.lastname: Ban
mesh_terms: D000818:Animals; D001243:Assisted Circulation; D001672:Biocompatible Materials; D002404:Catheterization; D002498:Centrifugation; D001026:Coronary Artery Bypass; D004285:Dogs; D004574:Electromagnetic Fields; D006354:Heart, Artificial; D006461:Hemolysis; D066298:In Vitro Techniques; D010974:Platelet Aggregation / Q000502:physiology; D011076:Polycarboxylate Cement / Q000378:metabolism; D013927:Thrombosis / Q000209:etiology
chemical_list: D001672:Biocompatible Materials; D011076:Polycarboxylate Cement; C005506:polycarbonate