Some pharmacological properties of Synclisia scabrida II.
The effect of the aqueous extract of S. scabrida on behaviour, and as an analgesic and antiulcer agent were studied. The extracts did not produce significant central nervous system action, or analgesia but had significant antiulcer activity against aspirin induced ulcer. The extract showed anticholinergic and antihistaminergic properties.
Orisakwe
O E
OE
Faculty of Medicine, College of Health Sciences, Nnamdi Azikiwe University, Nnewi Campus, Anambra, Nigeria.
Afonne
O J
OJ
Dioka
C E
CE
Ufearo
C S
CS
Okpogba
A N
AN
Ofoefule
S I
SI
D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001241:Aspirin; D018680:Cholinergic Antagonists / Q000494:pharmacology; D005260:Female; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D007082:Ileum / Q000187:drug effects; D008519:Medicine, Traditional; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy*
D000897:Anti-Ulcer Agents; D018680:Cholinergic Antagonists; D006634:Histamine H1 Antagonists; D010936:Plant Extracts; D001241:Aspirin