[The combined action of ionizing radiation and stress on antibody formation in mice].
Disturbances in humoral immune response to sheep erythrocytes after separate and combined effect of ionizing radiation (2 and 4 Gy) and stress (swimming for 10 of 60 min) was studied in mice. The increase in sensitivity to stress was found in irradiated mice. Superposition of undulating dynamics of post-stress immunosuppression on dynamics of post-radiation disorder was revealed. This is due to the different mechanisms of disturbances: redistribution of precursors of immunocompetent cells between immune organs in the first case and destruction of cells in the second case.
Surinov
B P
BP
Karpova
N A
NA
D000818:Animals; D000917:Antibody Formation / Q000528:radiation effects*; D000921:Antibody-Producing Cells / Q000276:immunology / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D007114:Immunization; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D005082:Physical Exertion / Q000528:radiation effects; D013154:Spleen / Q000276:immunology / Q000528:radiation effects; D013312:Stress, Physiological / Q000276:immunology*; D013550:Swimming; D013997:Time Factors; D014916:Whole-Body Irradiation / Q000009:adverse effects*
Sochetannoe vozdeĭstvie ioniziruiushcheĭ radiatsii i stressa na antitelogenez u mysheĭ.