[Significance of diagnosis and prognosis for breast carcinoma with examination of Ag-NORs].
The argyrophilic nucleolar organizer regions (Ag-NORs) was measured in the tissue sample aspirated with fine needle for 17 cases of breast benign lesion and 46 cases of breast cancer, by analysis of their micro-image with light microscope and computed. The results indicated that the amount of Ag-NORs in the nuclei of breast cancer was increased while the percentage of average areas occupied by Ag-NORs was decreased. It was significant statistically in comparing with benign lesion (P < 0.05). In addition, the amount of Ag-NORs in the nuclei of breast cancer with and that without metastasis was not different markedly (P > 0.05). However the percentage of average areas occupied by Ag-NORs was different statistically (P < 0.05). The conclusion of Ag-NORs is of benefit to distinguish from benign and malignant tumours of breast as well as significant for evaluating the prognosis for breast cancer.
Xiong
X
X
Department of Surgery, First Hospital of Beijing Medical University.
Huang
Y
Y
Wan
Y
Y
D000236:Adenoma / Q000175:diagnosis / Q000378:metabolism; D034961:Antigens, Nuclear; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009687:Nuclear Proteins / Q000378:metabolism*; D009697:Nucleolus Organizer Region / Q000378:metabolism; D011379:Prognosis
D034961:Antigens, Nuclear; D009687:Nuclear Proteins; C051963:nucleolar organizer region associated proteins