Blood lead dynamics of lead-exposed pregnant women and its effects on fetus development.
The dynamics of blood lead (Pb-B) and blood zinc protoporphyrin (ZPP-B) of women in early pregnancy and parturient women with lead exposure and the effects on fetus development were investigated. Pb-B of lead-exposed women was high: 0.984 mumol/L (20.38 micrograms/dl) and ZPP was 84.52 micrograms/dl. Cord blood Pb-B was 0.896 mumol/L (18.56 micrograms/dl) and cord blood ZPP was 69.24 micrograms/dl. In the control group, Pb-B was 0.261 mumol/L (5.41 micrograms/dl), ZPP-B, 37.59 micrograms/dl, cord blood, Pb-B 0.34 mumol/L (7.03 micrograms/dl), and cord ZPP-B 49.0 micrograms/dl. There was a significant correlation between blood lead and blood ZPP, maternal Pb-B and cord Pb-B, maternal Pb-B and cord ZPP-B. The significance of the consistency of high level Pb-B and the effects on fetus development is discussed.
Wan
B J
BJ
Department of Public Health, China Medical University, Shenyang, China.
Zhang
Y
Y
Tian
C Y
CY
Cai
Y
Y
Jiang
H B
HB
D000328:Adult; D002681:China; D005314:Embryonic and Fetal Development; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005313:Fetal Death / Q000209:etiology; D006801:Humans; D007854:Lead / Q000009:adverse effects / Q000097:blood*; D016014:Linear Models; D007752:Obstetric Labor, Premature / Q000209:etiology; D016273:Occupational Exposure; D011247:Pregnancy / Q000097:blood*; D011524:Protoporphyrins / Q000097:blood*
D011524:Protoporphyrins; C017803:zinc protoporphyrin; D007854:Lead