title: [Efficacy and safety of dexfenfluramine treatment in obese adolescents].
abstract: To assess the effect of dexfenfluramine on weight loss in obese adolescents, a group of 19 obese girls and boys was treated with a low calorie diet, supplemented with dexfenfluramine. The control group comprising the same number of patients was treated with diet only. Three weeks of hospitalization were followed by three weeks of treatment on an outpatient basis. An insignificantly larger weight loss in the dexfenfluramine-treated group was noted during the outpatient treatment. Dexfenfluramine therapy also resulted in a significant reduction of the serum triglycerides level. No serious side effects of dexfenfluramine therapy were noted.
authors.affiliation: Katedra i Klinika Endokrynologii Dzieciecej Slaskiej Akademii Medycznej w Katowicach.
authors.forename: E
authors.initials: E
authors.lastname: Małecka-Tendera
authors.forename: B
authors.initials: B
authors.lastname: Koehler
authors.forename: M
authors.initials: M
authors.lastname: Muchacka
authors.forename: R
authors.initials: R
authors.lastname: Wazowski
authors.forename: A
authors.initials: A
authors.lastname: Trzciakowska
mesh_terms: D000293:Adolescent; D002837:Chromaffin Granules; D002149:Energy Intake; D005260:Female; D005277:Fenfluramine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009765:Obesity / Q000188:drug therapy* / Q000534:rehabilitation; D014280:Triglycerides / Q000097:blood; D015431:Weight Loss
chemical_list: D014280:Triglycerides; D005277:Fenfluramine
vernacular_title: Skuteczność i bezpieczeństwo stosowania dexfenfluraminy u młodziezy z otyłościa prosta.