[Ultrastructural observation of tendonization of artificial tendon 109HH in rabbit].
Ten New Zealand rabbits were divided into 5 groups at random. Calcaneal tendons were cut bilaterally, then atificial tendon 109HH was used to connect the two ends of the cut tendon. Ultrastructural changes of control group and experimental groups at 2, 6, 12, 28 weeks after section were observed. The results showed that fibroblast proliferated and a lot of ribosome and RER appeared in plasm during 2 approximately 6 weeks, indicating artificial tendon caused fibroblast proliferation. During this period, fibroblast over synthesized collagenous protein and the synthesis of collagenous fibers peaked. During 12-28 weeks, the number of fibroblasts and the synthesis of collagenous protein decreased. Finally, fibroblasts became inactive tendon cells. With the formation of new tendons, the artificial tendens were degradated and absorbed, and disappeared after 12 weeks. The new tendon fibers became thicker and had the correct direction through reconstruction. The structure and function of new tendons could be restored to be consistent with normal values.
Liu
L
L
Division of Electronic Microscope, First Military Medical College, Guangzhou.
Cao
Q
Q
Xiao
H
H
D000818:Animals; D008854:Microscopy, Electron; D019736:Prostheses and Implants; D011817:Rabbits; D011897:Random Allocation; D012038:Regeneration; D013710:Tendons / Q000502:physiology / Q000648:ultrastructure*