title: [Application of catalytic model in sero-epidemiology of schistosomiasis].
abstract: The seroepidemiological data from two schistosomiasis japonica areas with different transmission levels was analysed using a Catalytic Model. The age-specific distribution of IgG antibody in the population of the two investigated settings was analysed with simple catalytic model, the curve equations are Y(A) = 0.876 (1--e-0.048t) and Y(B) = 5.71 (1--e-0.003t) respectively in the heavy- and mild-endemic areas. The age-specific distribution of IgM antibody was analysed with two-stage catalytic model, using a curve equations Y(A) = 2.13 (e-0.032t--e-0.047t) and Y(B) = 0.19 (e-0.012t--e-0.075t) respectively in both heavy-and mild-endemic areas. Based on the result of stool examination concurrently carried out with sera detection and the endemic situation in recent years, the results mentioned above were eligible for the analysis of seroepidemiological data on schistosomiasis to reveal the endemic situation, tendency and the characteristic of age-specific distribution, and in particular using a two-stage catalytic model to analyse IgM antibody. It could also be used for studies on endemic factors, evaluation on the efficiency of control programmes and for surveillance of endemicy.
authors.affiliation: Immunoparasitology Research Center, Zhejiang Medical University, Hangzhou.
authors.forename: Z L
authors.initials: ZL
authors.lastname: Wu
authors.forename: W C
authors.initials: WC
authors.lastname: Zhang
authors.forename: G T
authors.initials: GT
authors.lastname: Tan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002681:China / Q000453:epidemiology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008875:Middle Aged; D015233:Models, Statistical; D012554:Schistosomiasis japonica / Q000453:epidemiology*; D016036:Seroepidemiologic Studies
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M