title: [Vitrectomy with autoserum for idiopathic macular hole].
abstract: Using autoserum, we operated on eyes with full thickness macular hole and achieved greater anatomic and visual success than with eyes that underwent vitrectomy alone. A total of 34 eyes were treated with vitrectomy and fluid-gas exchange: 14 eyes with autoserum instillation and 15 eyes without autoserum. Five eyes with macular holes persisting after initial vitrectomy underwent reoperation with autoserum. After vitrectomy and fluid-air exchange, 0.1 to 0.3 ml of autoserum was placed for about 7 minutes over the hole, and then 30% SF6 was instilled. After treatment, successful anatomic closure occurred in 53% of the eyes without autoserum, in 86% of those with autoserum, and in 80% of those which underwent reoperation with autoserum. Visual acuity improved 2 lines or more in 53% of the eyes without autoserum, in 79% of those with autoserum, and in 60% of those that underwent reoperation with autoserum. The results of the current preliminary study shows that treatment of full-thickness macular holes with autoserum seems to be more beneficial than vitrectomy alone.
authors.affiliation: Department of Ophthalmology, Saitama Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Mori
authors.forename: S
authors.initials: S
authors.lastname: Yoneya
authors.forename: T
authors.initials: T
authors.lastname: Abe
mesh_terms: D001769:Blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000601:surgery*; D014821:Vitrectomy / Q000379:methods