title: Blood lead dynamics of lead-exposed pregnant women and its effects on fetus development.
abstract: The dynamics of blood lead (Pb-B) and blood zinc protoporphyrin (ZPP-B) of women in early pregnancy and parturient women with lead exposure and the effects on fetus development were investigated. Pb-B of lead-exposed women was high: 0.984 mumol/L (20.38 micrograms/dl) and ZPP was 84.52 micrograms/dl. Cord blood Pb-B was 0.896 mumol/L (18.56 micrograms/dl) and cord blood ZPP was 69.24 micrograms/dl. In the control group, Pb-B was 0.261 mumol/L (5.41 micrograms/dl), ZPP-B, 37.59 micrograms/dl, cord blood, Pb-B 0.34 mumol/L (7.03 micrograms/dl), and cord ZPP-B 49.0 micrograms/dl. There was a significant correlation between blood lead and blood ZPP, maternal Pb-B and cord Pb-B, maternal Pb-B and cord ZPP-B. The significance of the consistency of high level Pb-B and the effects on fetus development is discussed.
authors.affiliation: Department of Public Health, China Medical University, Shenyang, China.
authors.forename: B J
authors.initials: BJ
authors.lastname: Wan
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: C Y
authors.initials: CY
authors.lastname: Tian
authors.forename: Y
authors.initials: Y
authors.lastname: Cai
authors.forename: H B
authors.initials: HB
authors.lastname: Jiang
mesh_terms: D000328:Adult; D002681:China; D005314:Embryonic and Fetal Development; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005313:Fetal Death / Q000209:etiology; D006801:Humans; D007854:Lead / Q000009:adverse effects / Q000097:blood*; D016014:Linear Models; D007752:Obstetric Labor, Premature / Q000209:etiology; D016273:Occupational Exposure; D011247:Pregnancy / Q000097:blood*; D011524:Protoporphyrins / Q000097:blood*
chemical_list: D011524:Protoporphyrins; C017803:zinc protoporphyrin; D007854:Lead