title: [The morphological changes in the liver in experimentally induced hypercholesterolemia].
abstract: The authors examined the liver of 20 rabbits "Newzeland white" and "Chinchila", undergone atherogenic diet with cholesterol (0.3-0.5 g/kg body weight) for 30 and 60 days. They determined cholesterol, lipids, triglicerides and beta-lipoproteins in the serum. The morphologic study revealed accumulation of cholesterol in the hepatocytes, fibrosis, proliferation of the bile ducts and signs of hepatic cirrhosis.
authors.affiliation: Department of Pathological Anatomy, Higher Medical School, Sofia.
authors.forename: Ts
authors.initials: Ts
authors.lastname: Boshnakova
authors.forename: A
authors.initials: A
authors.lastname: Georgiev
authors.forename: D
authors.initials: D
authors.lastname: Strashimirov
mesh_terms: D000818:Animals; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D006937:Hypercholesterolemia / Q000097:blood / Q000139:chemically induced / Q000473:pathology*; D008055:Lipids / Q000097:blood; D008099:Liver / Q000648:ultrastructure*; D008854:Microscopy, Electron; D011817:Rabbits; D013997:Time Factors
chemical_list: D002791:Cholesterol, Dietary; D008055:Lipids
vernacular_title: Morfologichni promeni v cherniia drob pri eksperimentalno predizvikana khiperkholesterolemiia.