[Diarrhea due to microsporidia in a patient with AIDS].
A 26-year-old male AIDS patient with diarrhea of two-months evolution is reported here. The most relevant intestinal pathogens, including Cryptosporidium parvum, were ruled out by routine microbiological tests. Stool samples stained with an "oblong" Ziehl-Neelsen method (fucsin, 7 min instead of 3 min) allowed visualization of organisms resembling microsporidia. Both modified trichrome and calcofluor stains showed organisms compatible with Enterocytozoon bieneusi. Significant titer of antibodies (> or = 1/800) against 4 different microsporidial species were obtained from the serum of the patient by an ELISA test. Clinical improvement was observed after treatment with albendazole, 400 mg twice daily for 4 weeks, even though microsporidial spores were still detected in stool specimens. To our knowledge, this is the first microsporidial infection reported in Argentina.
Bantar
C
C
Laboratorio de Microbiología, Clínicas Dr. Norberto Quirno (CEMIC), Buenos Aires, Argentina.
Herrera
F
F
Didier
E
E
Falco
A
A
Bianchini
H
H
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000473:pathology; D000328:Adult; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D003967:Diarrhea / Q000209:etiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000382:microbiology; D006801:Humans; D008297:Male; D016816:Microsporida / Q000276:immunology; D016881:Microsporidiosis / Q000150:complications*
D000907:Antibodies, Bacterial
Diarrea por microsporidia en un enfermo con SIDA.