Quantitative analysis of the tomographic technetium-99m MIBI (99mTc-MIBI) myocardial bullseye display: application to diagnosis of coronary artery disease.
In this study, the 99mTc-MIBI myocardial bullseye display of 31 healthy persons and 34 patients with myocardial ischemia and 17 patients with myocardial infarction were analyzed quantitatively; and compared with the results of myocardial tomography analysis and qualitative bullseye analysis. The sensitivities of the three methods were 88.2%, 91.2% and 94.1% respectively (P > 0.05), and the specificities were 93.5%, 83.9% and 83.9% respectively (P < 0.05). On the other hand, the quantitative analysis obviously outperformed the other two methods in the detection of ischemic segments of myocardium near infarction zone (P < 0.01). The quantitative analysis of 99mTc-MIBI myocardial bullseye (quantitative bullseye) was an objective, specific and sensitive method for diagnosis of coronary artery disease.
Gao
Z R
ZR
Department of Nuclear Medicine, Xiehe Hospital, Tongji Medical University, Wuhan.
Zhang
Y X
YX
Hu
J
J
Xu
W D
WD
D000328:Adult; D000368:Aged; D003287:Contrast Media; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
D003287:Contrast Media; D017256:Technetium Tc 99m Sestamibi