Adrenal gland leiomyoma in a child with acquired immunodeficiency syndrome.
An adrenal gland leiomyoma was incidentally found at autopsy in a 2-year-old boy with acquired immunodeficiency syndrome (AIDS). Smooth muscle neoplasms have been described in pediatric AIDS and affect mainly the tracheobronchopulmonary, gastrointestinal, and hepatobiliary systems. An association between Epstein-Barr virus (EBV) and smooth muscle tumors in patients with AIDS has been described. This case is the first leiomyoma to be reported in the adrenal gland of a child with AIDS. EBV genome was demonstrated in the tumor by polymerase chain reaction.
Jimenez-Heffernan
J A
JA
Department of Pathology, Hospital La Paz, Madrid, Spain.
Hardisson
D
D
Palacios
J
J
Garcia-Viera
M
M
Gamallo
C
C
Nistal
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000199:Actins / Q000032:analysis; D000310:Adrenal Gland Neoplasms / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology; D002675:Child, Preschool; D004279:DNA, Viral / Q000737:chemistry; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D007889:Leiomyoma / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D016133:Polymerase Chain Reaction
D000199:Actins; D004279:DNA, Viral