title: Oral soft tissue manifestations and CD4 lymphocyte counts in HIV-infected children.
abstract: This study investigated the prevalence of oral soft tissue lesions in children infected with HIV and the relationship of CD4 lymphocyte levels with the prevalence of those lesions. Sixty HIV-positive children enrolled in the Children's Hospital AIDS Program (age 5.8 +/- 3 years) were selected for study. Only five subjects (8%) had healthy gingiva and a low mean plaque index (22%). The remainder had gingivitis or periodontitis with relatively high plaque indices (47, 55, and 94%, respectively). A declining CD4 lymphocyte count (1357 to 35) was associated with an increasing severity of gingival disease.
authors.affiliation: Department of Oral Pathology, Biology and Diagnostic Sciences, New Jersey Dental School, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Howell
authors.forename: J J
authors.initials: JJ
authors.lastname: Jandinski
authors.forename: P
authors.initials: P
authors.lastname: Palumbo
authors.forename: Z
authors.initials: Z
authors.lastname: Shey
authors.forename: M I
authors.initials: MI
authors.lastname: Houpt
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology* / Q000473:pathology; D000293:Adolescent; D018791:CD4 Lymphocyte Count; D002648:Child; D002675:Child, Preschool; D003774:Dental Plaque Index; D005260:Female; D005884:Gingival Hemorrhage / Q000473:pathology; D005891:Gingivitis / Q000276:immunology / Q000473:pathology; D015658:HIV Infections / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009059:Mouth Diseases / Q000276:immunology* / Q000473:pathology; D017622:Periodontal Attachment Loss / Q000473:pathology; D010518:Periodontitis / Q000473:pathology; D015995:Prevalence