title: [Cholelithiasis in the patient with cirrhosis of the liver: surgical aspects].
abstract: Open cholecystectomy in cyrrotic patients with good liver functions has operative mortality similar to normal subject (0.5-1%), while in patients with severe hepatic cyrrosis mortality varies between 7 and 83%. In this study we have evaluated the post operative results in cyrrotic patients undergone to open cholecistectomy in order to evaluate indications, controindications and risk factors related to surgery. In the last 7 years 34 patients with liver cyrrosis have been operated for biliary calculi, one of them had laparoscopic cholecystectomy. Morbidity was 29.4% (10 cases) mortality 8.8% (3 cases). Jaundice was the main indication for emergency (66.6%) in the two cases it was related to uncompensated liver functions. Endoscopic Retrograde Cholangio-Pancreatography (ERCP) can demonstrate today the causes of jaundice avoiding unecessary operations. Post operative evaluations of our series confirm that operative risk is strictly related to epatic disease and to an appropriate surgical option. Moreover patients with compensated liver cyrrosis, (Child A), do not represent anymore a controindication to laparoscopic cholecystectomy that has less septic post operative complications when compared to open surgery.
authors.affiliation: Clinica Chirurgica, Università degli Studi di L'Aquila.
authors.forename: M
authors.initials: M
authors.lastname: Schietroma
authors.forename: T
authors.initials: T
authors.lastname: Di Cosimo
authors.forename: C
authors.initials: C
authors.lastname: De Santis
authors.forename: E
authors.initials: E
authors.lastname: Chichiarelli
authors.forename: R
authors.initials: R
authors.lastname: Flamini
authors.forename: A
authors.initials: A
authors.lastname: Risetti
authors.forename: B
authors.initials: B
authors.lastname: Ciuca
authors.forename: G
authors.initials: G
authors.lastname: Cofini
authors.forename: F
authors.initials: F
authors.lastname: Carlei
authors.forename: M
authors.initials: M
authors.lastname: Simi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical; D002763:Cholecystectomy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D017114:Liver Failure, Acute / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018805:Sepsis / Q000209:etiology; D016896:Treatment Outcome
vernacular_title: La calcolosi della colecisti nel paziente con cirrosi epatica: aspetti di interesse chirurgico.