[Increase in oxygen-transporting efficiency of hemoglobin when chemically modified].
Polycondensation of human hemoglobin with glutaraldehyde premodified with reagents bearing acid groups (glutamic acid or sodium bisulfite), has been carried out. The resulting modified hemoglobin displays better oxygen transport characteristics in comparison with native hemoglobin.
Kuznetsova
N P
NP
Gudkin
L R
LR
Mishaeva
R N
RN
D000494:Allosteric Regulation; D001692:Biological Transport; D005976:Glutaral / Q000737:chemistry; D006454:Hemoglobins / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D010100:Oxygen / Q000378:metabolism*; D011485:Protein Binding; D011732:Pyridoxal Phosphate / Q000378:metabolism
D006454:Hemoglobins; D011732:Pyridoxal Phosphate; D010100:Oxygen; D005976:Glutaral
Povyshenie kislorodtransportnoĭ éffektivnosti gemoglobina pri ego khimicheskoĭ modifikatsii.