title: Sequence analysis of the human DNA flanking sites of human immunodeficiency virus type 1 integration.
abstract: Human immunodeficiency virus type 1 (HIV-1) tagged with the Escherichia coli supF gene has been used to clone integrated HIV-1 proviruses. Sequence analysis of the 600 to 800 bp of human DNA adjacent to 29 clones revealed a propensity for HIV-1 to integrate near the Alu class of human repetitive elements.
authors.affiliation: Department of Microbiology and Immunology, University of North Carolina at Chapel Hill 27599-7295, USA.
authors.forename: S W
authors.initials: SW
authors.lastname: Stevens
authors.forename: J D
authors.initials: JD
authors.lastname: Griffith
mesh_terms: D010582:Bacteriophage lambda / Q000235:genetics; D001483:Base Sequence; D003001:Cloning, Molecular; D016384:Consensus Sequence; D004247:DNA / Q000737:chemistry / Q000235:genetics*; D004279:DNA, Viral / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D017353:Gene Deletion; D005798:Genes, Bacterial; D016153:Genes, Suppressor; D015754:Genes, nef; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D011533:Proviruses / Q000235:genetics; D012343:RNA, Transfer / Q000096:biosynthesis; D012091:Repetitive Sequences, Nucleic Acid; D016662:Virus Integration
chemical_list: D004279:DNA, Viral; C096275:supF tRNA; D004247:DNA; D012343:RNA, Transfer