[Toxicity of vanadium to Leydig cells in vitro].
The levels of testosterone secreted by rat's Leydig cells in varied concentrations of V2O5 (0.125, 0.,25, 0.5, 2 and 3 mmol/L) were assayed. The result showed there was no obvious relation between the level of testosterone and the concentration of V2O5. This in vitro study in accord with the result of whole animal research indicates that Leydig cell is not the target of V2O5.
Li
H
H
Department of Environment Hygiene, Second Military Medical University.
Yang
Z
Z
Zhang
T
T
D000818:Animals; D002478:Cells, Cultured; D007985:Leydig Cells / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013739:Testosterone / Q000378:metabolism; D017968:Vanadium Compounds / Q000633:toxicity*
D017968:Vanadium Compounds; D013739:Testosterone; C066075:vanadium pentoxide