Tracking antigen-specific helper T cell responses.
T-cell receptor transgenic animals provide an excellent source of T cells for the analysis of antigen-specific helper T-cell development. Alternatively, studies in normal animals continue to focus on specific immune responses dominated by T cells using restricted sets of antigen receptors. These complementary strategies provide direct access to the dynamics of helper T-cell differentiation in vivo.
McHeyzer-Williams
M G
MG
Duke University Medical Center, Department of Immunology, Durham, NC 27710, USA. mchey002@acpub.duke.edu
Altman
J D
JD
Davis
M M
MM
D000818:Animals; D000939:Epitopes / Q000032:analysis* / Q000276:immunology*; D006801:Humans; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*
D000939:Epitopes