[False high levels glycosylated hemoglobin in 2 diabetic patients with persistence of fetal hemoglobin].
Two diabetic patients with unusual high levels of glycosylated hemoglobin measured by ion exchange chromatography are described. Further studies revealed a persistence of fetal hemoglobin in both cases. This condition produces falsely high levels of glycosylated hemoglobin, when ion exchange chromatography is used. These cases may be overtreated with risk of hypoglycemia. Patients with inappropriate levels of glycosylated hemoglobin should be investigated for hemoglobinopathies.
Villanueva
C L
CL
Servicio de Medicina, Hospital del Salvador, Santiago de Chile.
Zavala
C
C
Alcayaga
M P
MP
D000328:Adult; D002852:Chromatography, Ion Exchange; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000235:genetics; D016883:Diabetic Ketoacidosis / Q000097:blood* / Q000235:genetics; D004588:Electrophoresis, Cellulose Acetate; D005260:Female; D005319:Fetal Hemoglobin / Q000032:analysis*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008875:Middle Aged
D005319:Fetal Hemoglobin; D006442:Glycated Hemoglobin
Concentraciones falsamente elevadas de hemoglobina glicosilada en 2 pacientes diabéticos con hemoglobina fetal persistente.