title: Patients with schizophrenia remember that an event has occurred, but not when.
abstract: BACKGROUND
  The context memory deficit hypothesis of schizophrenia postulates that the long-term deficit associated with this disorder is related to a memory impairment for contextual information.
  
  
  METHODS
  To test this hypothesis, memory for temporal context was assessed in 33 patients with schizophrenia and 33 normal subjects, using a recency discrimination task.
  
  
  RESULTS
  Whereas patients were able to recall and recognise target items, they were unable to recognise from among the target items those which had been most recently learned.
  
  
  CONCLUSIONS
  Schizophrenia is associated with a temporal context memory deficit.
authors.affiliation: INSERM Unité 405, Hôpitaux Universitaires de Strasbourg, France.
authors.forename: L
authors.initials: L
authors.lastname: Rizzo
authors.forename: J M
authors.initials: JM
authors.lastname: Danion
authors.forename: M
authors.initials: M
authors.lastname: van der Linden
authors.forename: D
authors.initials: D
authors.lastname: Grangé
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001245:Association Learning / Q000187:drug effects; D001288:Attention / Q000187:drug effects; D018680:Cholinergic Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D004193:Discrimination Learning / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000187:drug effects; D008875:Middle Aged; D010364:Pattern Recognition, Visual / Q000187:drug effects; D012153:Retention, Psychology / Q000187:drug effects; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy; D012565:Schizophrenic Psychology; D013998:Time Perception / Q000187:drug effects; D014888:Wechsler Scales
chemical_list: D014150:Antipsychotic Agents; D018680:Cholinergic Antagonists