title: Annosenegalin and annogalene: two cytotoxic mono-tetrahydrofuran acetogenins from Annona senegalensis and Annona cherimolia.
abstract: Two new cytotoxic mono-tetrahydrofuran acetongenins, annosenegalin and annogalene, have been isolated from the cytotoxic methanolic extract of Annona senegalensis and A. cherimolia seeds. Their structures were established on the basis of 1D and 2D NMR spectroscopic techniques. Annosenegalin belongs to the rare type of C37 mono-tetrahydrofuran acetogenins, and annogalene is an olefinic acetogenin.
authors.affiliation: Departamento de Farmacología, Universidad de Valencia, Burjasot, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Sahpaz
authors.forename: M C
authors.initials: MC
authors.lastname: González
authors.forename: R
authors.initials: R
authors.lastname: Hocquemiller
authors.forename: M C
authors.initials: MC
authors.lastname: Zafra-Polo
authors.forename: D
authors.initials: D
authors.lastname: Cortes
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents; D009682:Magnetic Resonance Spectroscopy; D016488:Medicine, African Traditional; D010946:Plants, Medicinal; D012639:Seeds; D012675:Senegal; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D000970:Antineoplastic Agents