Recanalization of totally occluded saphenous vein grafts using local urokinase delivery with the Dispatch catheter.
Current techniques for the percutaneous revascularization of totally occluded vein grafts are limited by a low initial success rate, a significant incidence of distal embolization, and a high rate of early graft reclosure. This case report describes two patients in whom graft recanalization was attempted with the combined use of balloon angioplasty/intra-graft stent placement and local urokinase delivery using a new angiotherapy catheter. Successful recanalization was achieved in both patients without major complications, in spite of a large thrombus burden as demonstrated by angiography.
Glazier
J J
JJ
Department of Internal Medicine, Hartford Hospital, University of Connecticut 06102, USA.
Bauer
H H
HH
Kiernan
F J
FJ
Primiano
C A
CA
Mitchel
J F
JF
Dougherty
J E
JE
Waters
D D
DD
McKay
R G
RG
D015906:Angioplasty, Balloon, Coronary; D003327:Coronary Disease / Q000209:etiology / Q000628:therapy*; D006083:Graft Occlusion, Vascular / Q000150:complications / Q000628:therapy*; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D010960:Plasminogen Activators / Q000008:administration & dosage*; D012501:Saphenous Vein; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator