title: [The effect of angioplasty on cerebral vasomotor reactivity in patients with important stenosis of the internal carotid artery].
abstract: BACKGROUND
  We present the preliminary results of the effects on percutaneous translumenal angioplasty (PTA) cerebral haemodynamics in thirty patients with important stenosis of the internal carotidal artery.
  
  
  METHODS
  Using transcranial doppler (TCD) with acetazolamide (ACZ) as a vasodilatory stimulus, we assessed vasomotor reactivity (VR and pulsatility index (Pl) both before and three months after angioplasty. We also carried out single photon emission computerized tomography (SPECT) and cartography and frequency measurement by electroencephalogram (EEG) again both before and after PTA.
  
  
  RESULTS
  Of the first twelve patients who completed the study, VR was maintained in nine and PI increased after PTA in seven. In three patients VR was exhausted and in two recovered after PTA.
  
  
  CONCLUSIONS
  PTA improved cerebral haemodynamics. Similar more exhaustive studies are needed if revascularization techniques are to be useful in treating patients with this level of stenosis but who are asymptomatic as to the risk of haemodynamic cerebral vasomotor angioplasty.
authors.affiliation: Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla.
authors.forename: C
authors.initials: C
authors.lastname: Arenas
authors.forename: A
authors.initials: A
authors.lastname: Gil-Peralta
authors.forename: A
authors.initials: A
authors.lastname: Otero
authors.forename: P
authors.initials: P
authors.lastname: Crespo
mesh_terms: D000086:Acetazolamide; D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D000927:Anticonvulsants; D001921:Brain / Q000098:blood supply / Q000503:physiopathology / Q000601:surgery; D002343:Carotid Artery, Internal / Q000503:physiopathology / Q000601:surgery*; D016893:Carotid Stenosis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015899:Tomography, Emission-Computed, Single-Photon; D017585:Ultrasonography, Doppler, Transcranial
chemical_list: D000927:Anticonvulsants; D000086:Acetazolamide
vernacular_title: Efecto de la angioplastia en la reactividad vasomotora cerebral de pacientes con estenosis significativa de la arteria carótida interna.