[The effect of changes in the level of interoceptive afferentation on the spontaneous periodic motor activity of rat pups].
The effect of intraperitoneally injected (25 mg/kg) novocaine (procaine) on the spontaneous periodic motor activity was investigated in rat puppies ageing from 1 to 14 days. It was shown that reactions were phasic: initial continuous and then elevated activity was followed by depression and recovery. The duration and intensity of stimulation and depression decrease with age. It was concluded that in newborn animals an excitability of motor centers depends on the level of interoceptive afferentation. The last may be one of the motor activity regulation mechanisms. The role of this mechanism decreases with age in favour of extero- and proprioception mechanisms of motor control.
Kulaev
B S
BS
Bursian
A V
AV
Semenova
Iu O
IuO
D000344:Afferent Pathways / Q000187:drug effects / Q000502:physiology; D000375:Aging / Q000187:drug effects / Q000502:physiology; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D000831:Animals, Newborn; D004562:Electrocardiography / Q000187:drug effects; D004576:Electromyography / Q000187:drug effects; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology*; D010507:Periodicity; D011343:Procaine / Q000494:pharmacology; D011434:Proprioception / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar
D000779:Anesthetics, Local; D011343:Procaine
Vliianie izmeneniia urovnia interotseptivnoĭ afferentatsii na spontannuiu periodicheskuiu motornuiu aktivnost' krysiat.