title: A comparison of referral patterns and characteristics of patients with first episode symptomatic genital HSV-1 and HSV-2 infections in Sheffield.
abstract: OBJECTIVE
  To ascertain factors associated with HSV-1 and HSV-2 isolates in patients attending a genitourinary medicine clinic with symptomatic first episode genital herpes (FEGH).
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  A total of 606 females and 333 males presenting with culture positive FEGH between 1990-94.
  
  
  METHODS
  Department of Genitourinary Medicine, Royal Hallamshire Hospital, Sheffield, UK.
  
  
  METHODS
  Group comparison of referral patterns, demographic data, prior and concurrent episodes of STD, recent partner change.
  
  
  RESULTS
  HSV-1 infected patients of either sex were more likely to be general practitioner (GP) referred, to be white, and less likely to have had preceding STD episodes. Recent sexual partner change had occurred significantly more often in HSV-2 infected females but there was no similar difference between HSV-1 and HSV-2 infected males.
  
  
  CONCLUSIONS
  The relative HSV-1:HSV-2 isolate ratio in FEGH is influenced by the referral patterns. HSV-1 isolates predominate in patients presenting to GPs who refer the patients to GUM clinics for accurate diagnosis, counselling, follow up and screening for other STDs.
authors.affiliation: Department of Gentioruinary Medicine, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: A
authors.initials: A
authors.lastname: Nageswaran
authors.forename: R N
authors.initials: RN
authors.lastname: Shen
authors.forename: J
authors.initials: J
authors.lastname: Craig
authors.forename: T T
authors.initials: TT
authors.lastname: Kyi
authors.forename: C J
authors.initials: CJ
authors.lastname: Priestley
authors.forename: G R
authors.initials: GR
authors.lastname: Kinghorn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004739:England / Q000453:epidemiology; D005194:Family Practice; D005260:Female; D006558:Herpes Genitalis / Q000453:epidemiology* / Q000208:ethnology / Q000821:virology; D018259:Herpesvirus 1, Human / Q000302:isolation & purification; D018258:Herpesvirus 2, Human / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D012017:Referral and Consultation / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012737:Sex Factors; D012747:Sexual Partners