Iron acquisition in the pathogenic Neisseria.
Pathogenic Neisseria species need to obtain iron from the host to grow in vivo. Several iron-transport systems are known, and regulation of Neisseria iron-transport genes occurs via the transcriptional regulator Fur. There is evidence that the ability to transport iron is crucial to the survival of these organisms in vivo.
Genco
C A
CA
Dept of Microbiology and Immunology, Morehouse School of Medicine, Atlanta, GA 30310-1495, USA. genco@link.msm.edu
Desai
P J
PJ
D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000502:physiology; D001483:Base Sequence; D001692:Biological Transport; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008969:Molecular Sequence Data; D009343:Neisseria / Q000378:metabolism* / Q000472:pathogenicity
D001425:Bacterial Outer Membrane Proteins; D007501:Iron