title: [Neuromediator systems in the mechanisms of remission and recurrence in alcoholism].
abstract: Experiments on chronically alcoholic rats have revealed profound changes in the properties of the brain dopamine, serotonin, GABA and opiate systems 48 hours and 2 months of alcohol deprivation. With this, a single administration of ethanol showed its increased sensitivity of striatal and hippocampal receptors both during short- and long-term alcohol deprivation, the properties of these receptors tended towards recovery. It may be suggested that the above changes in the receptor apparatus of the neurotransmitter systems underlie the mechanism of remission and recurrence in alcoholism.
authors.forename: N L
authors.initials: NL
authors.lastname: Vekshina
authors.forename: A G
authors.initials: AG
authors.lastname: Veretinskaia
authors.forename: T T
authors.initials: TT
authors.lastname: Bondarenko
authors.forename: I P
authors.initials: IP
authors.lastname: Anokhina
mesh_terms: D000437:Alcoholism / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism; D000431:Ethanol / Q000009:adverse effects; D008297:Male; D018377:Neurotransmitter Agents / Q000378:metabolism*; D051381:Rats; D017981:Receptors, Neurotransmitter / Q000378:metabolism; D012008:Recurrence; D012075:Remission, Spontaneous; D013375:Substance Withdrawal Syndrome / Q000378:metabolism; D013997:Time Factors
chemical_list: D018377:Neurotransmitter Agents; D017981:Receptors, Neurotransmitter; D000431:Ethanol
vernacular_title: Neĭromediatornye sistemy v mekhanizmakh remissii i retsidiva pri alkogolizme.