title: [Botulinum A toxins in the treatment of spasticity in cerebral palsy during childhood].
abstract: We evaluated the safety and efficacy of Botulinum- A toxin (BTX) in patients with equinus deformity associated with cerebral palsy (CP). We prescribed BTX to six patients (all of whom had previously participated in a multicenter, randomized, double blind study of the same drug); treatment continued for at least 15 months. Four children showed striking improvement, being converted from toe-toe to consistent or occasional heel-toe gait. No side effects were observed. BTX appears to be safe and effective in patients with CP.
authors.affiliation: Servicios de Neurología, Fundación Jiménez Díaz, Madrid.
authors.forename: P J
authors.initials: PJ
authors.lastname: García Ruiz
authors.forename: V
authors.initials: V
authors.lastname: Sánchez Bernardos
authors.forename: V
authors.initials: V
authors.lastname: Urcelay
authors.forename: V
authors.initials: V
authors.lastname: San Martín
authors.forename: F
authors.initials: F
authors.lastname: Castillo
authors.forename: A
authors.initials: A
authors.lastname: Ferrer
authors.forename: J
authors.initials: J
authors.lastname: Campos
authors.forename: J
authors.initials: J
authors.lastname: García de Yébeñes
mesh_terms: D000293:Adolescent; D001905:Botulinum Toxins / Q000627:therapeutic use*; D002547:Cerebral Palsy / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D018678:Cholinergic Agents / Q000627:therapeutic use*; D004863:Equinus Deformity / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D018678:Cholinergic Agents; D001905:Botulinum Toxins
vernacular_title: Tratamiento de la espasticidad asociada a parálisis infantil con toxina botulínica.