Prospective studies on the relationship between the 50 g glucose challenge test and pregnant outcome.
The 50 g oral glucose challenge test (50gGCT) was performed on 622 pregnant women, and 75 g oral glucose tolerance test (75gGTT) was further done on subjects with screening tests value of > or = 7.78 mmol/L. The results showed that there were 16.56% (103/622) women with screening value of > or = 7.78 mmol/L, among whom, 32 were identified as having gestational impaired glucose tolerance (GIGT) and 12, gestational diabetes mellitus (GDM) by confirmatory test of 75gGTT. The sensitivity of 50gGCT was 42.72%(44/103). The incidences of edema-proteinuria-hypertension syndrome (EPH-syndrome), premature rupture of membranes, fetal macrosomia, operative deliveries and perinatal morbidity were higher in women with GIGT/GDM than in women without GIGT/GDM. It suggests that 50gGCT is an ideal method of screening for GDM and should be performed on all pregnant women.
Sun
B
B
Department of Obstetrics and Gynecology, Qingdao Municipal Hospital.
Wang
X
X
Song
Q
Q
Wang
Y
Y
Xue
L
L
Wang
C
C
Quan
Z
Z
Zhang
Y
Y
Niu
P
P
D000328:Adult; D016640:Diabetes, Gestational / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005320:Fetal Macrosomia / Q000150:complications; D005322:Premature Rupture of Fetal Membranes / Q000150:complications; D018149:Glucose Intolerance / Q000150:complications / Q000175:diagnosis*; D005951:Glucose Tolerance Test / Q000379:methods; D006801:Humans; D011225:Pre-Eclampsia / Q000150:complications; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies