Adverse reaction to pseudoephedrine.
A patient developed a scarlatina-like rash on two separate occasions after receiving a dose of pseudoephedrine. Patch tests with this substance and other structurally related substances (i.e. ephedrine, phenylephrine, and epinephrine) were negative. The oral test with pseudoephedrine provoked a new episode. It is difficult to clarify the exact mechanism of the described reaction; the nature of this eruption probably resembles many other drug-induced adverse reactions in which there is no certainty if mechanisms of type I or III are involved.
Rochina
A
A
Allergy Department, Hospital Clinic Universitari, Valencia, Spain.
Burchés
E
E
Morales
C
C
Brasó
J V
JV
Pelaéz
A
A
D000328:Adult; D003875:Drug Eruptions / Q000209:etiology*; D004809:Ephedrine / Q000009:adverse effects*; D005260:Female; D006801:Humans
D004809:Ephedrine