title: [One center's experience with fibrinolytic treatment in children].
abstract: Fifteen children treated with fibrinolytic agents are presented. The most frequent indication was thromboembolic disease (TED). Eleven patients received streptokinase, 5-urokinase and 3-tissue plasminogen activator. Concomitant heparin was administered to 9 patients with TED. Total resolution was achieved in 9 children, partial improvement in 5; 1 child died during treatment without any improvement. Bleeding complications were observed in 6 patients, 1 of them died due to haemorrhagic stroke. According to the literature and our own experience, we recommend fibrinolytic agents as the treatment of choice for severe TED also in children.
authors.affiliation: II Klinika Chorób Dzieci Instytutu Pediatrii Akademii Medycznej w Poznaniu.
authors.forename: T
authors.initials: T
authors.lastname: Jarmoliński
authors.forename: J
authors.initials: J
authors.lastname: Zachwieja
authors.forename: M
authors.initials: M
authors.lastname: Kaczmarek-Kanold
authors.forename: T
authors.initials: T
authors.lastname: Raysner
authors.forename: J
authors.initials: J
authors.lastname: Stachowski
authors.forename: E
authors.initials: E
authors.lastname: Bortkiewicz
authors.forename: E
authors.initials: E
authors.lastname: Stefaniak
authors.forename: M
authors.initials: M
authors.lastname: Warzywoda
authors.forename: A
authors.initials: A
authors.lastname: Siwińska
authors.forename: J
authors.initials: J
authors.lastname: Maciejewski
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013300:Streptokinase / Q000627:therapeutic use*; D013923:Thromboembolism / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014463:Ultrasonography; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging / Q000503:physiopathology
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Leczenie fibrynolityczne u dzieci: doświadczenia własne.