title: Synthesis and antifungal activity of cinnamic acid esters.
abstract: Cinnamic, p-coumaric and ferulic acids were isolated from pineapple stems (Ananas comosus var. Cayenne). Twenty-four kinds of esters were prepared from these acids, alcohols and the components of Alpinia. Isopropyl 4-hydroxycinnamate (11) and butyl 4-hydroxycinnamate (12) were found to have almost the same effectiveness in antifungal activity against Pythium sp. at 10 ppm as that of the commercial fungicide iprobenfos (kitazin P).
authors.affiliation: Department of Bioscience and Biotechnology, College of Agriculture, University of the Ryukyus, Okinawa, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Tawata
authors.forename: S
authors.initials: S
authors.lastname: Taira
authors.forename: N
authors.initials: N
authors.lastname: Kobamoto
authors.forename: J
authors.initials: J
authors.lastname: Zhu
authors.forename: M
authors.initials: M
authors.lastname: Ishihara
authors.forename: S
authors.initials: S
authors.lastname: Toyama
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D002934:Cinnamates / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D003373:Coumaric Acids / Q000737:chemistry / Q000302:isolation & purification; D004952:Esters; D005638:Fruit / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018547:Plant Stems / Q000737:chemistry; D011422:Propionates; D011775:Pythium / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D002934:Cinnamates; D003373:Coumaric Acids; D004952:Esters; D010936:Plant Extracts; D011422:Propionates; C029010:cinnamic acid; C004999:ferulic acid; C495469:p-coumaric acid