title: Quinolone resistance in Oligella urethralis-associated chronic ambulatory peritoneal dialysis peritonitis.
abstract: Oligella urethralis is an organism which is normally isolated as a commensal from the genitourinary tract. We describe the first two reported cases of CAPD-associated peritonitis caused by this organism. Both isolates were found to be resistant to ciprofloxacin, while relatively sensitive to a wide range of antimicrobial drugs. These findings indicate that this organism may be an opportunistic pathogen for CAPD patients, and that extensive ciprofloxacin usage provides a selection pressure for emergence of resistance.
authors.affiliation: Diagnostic Bacteriology Department, St Mary's Hospital, London, UK.
authors.forename: U B
authors.initials: UB
authors.lastname: Riley
authors.forename: G
authors.initials: G
authors.lastname: Bignardi
authors.forename: L
authors.initials: L
authors.lastname: Goldberg
authors.forename: A P
authors.initials: AP
authors.lastname: Johnson
authors.forename: B
authors.initials: B
authors.lastname: Holmes
mesh_terms: D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D002939:Ciprofloxacin / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D006801:Humans; D008297:Male; D009016:Moraxella / Q000187:drug effects*; D016870:Neisseriaceae Infections / Q000188:drug therapy*; D015242:Ofloxacin / Q000627:therapeutic use; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000209:etiology*
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D015242:Ofloxacin