Transcutaneous metal absorption following chemical burn injury.
A 33-year-old metal refinery worker sustained a 40 per cent TBSA burn injury from a mixture containing acids and salts of nickel and cobalt. High levels of both nickel and cobalt were detected in both serum and urine, necessitating treatment with EDTA, a chelating agent. No detrimental effects of either nickel or cobalt have so far been detected, though the patient is being followed in the long term.
Neligan
P C
PC
Department of Surgery, University of Toronto, Canada.
D000062:Accidents, Occupational; D000328:Adult; D001830:Body Surface Area; D002057:Burns, Chemical / Q000209:etiology / Q000378:metabolism*; D002614:Chelating Agents / Q000627:therapeutic use; D003035:Cobalt / Q000009:adverse effects / Q000097:blood / Q000378:metabolism* / Q000506:poisoning / Q000652:urine; D004492:Edetic Acid / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009532:Nickel / Q000009:adverse effects / Q000097:blood / Q000378:metabolism* / Q000506:poisoning / Q000652:urine; D012869:Skin Absorption
D002614:Chelating Agents; D003035:Cobalt; C029938:nickel sulfate; D009532:Nickel; D004492:Edetic Acid; C026305:cobalt sulfate; C030989:nickel carbonate