Long-term results after colectomy and ileoanal pull-through procedure in children.
OBJECTIVE
To review the clinical experience with colectomy and ileoanal pull-through procedure in children from 1 hospital.


METHODS
Since 1977, 116 children 18 years of age or younger underwent colectomy and ileoanal pull-through procedure at University of California-Los Angeles Medical Center. Ninety-four children had ulcerative colitis, 17 had familial polyposis coli, and 5 had Hirschsprung disease. Sixty-two children had a lateral pouch, 47 a J-pouch, and 7 a straight pull-through. A diverting ileostomy was used for 4 months for all patients except 9 with polyposis coli and 2 with Hirschsprung disease. During the same period, an additional 414 patients older than 18 years underwent the ileoanal pull-through procedure.


RESULTS
Forty-eight children (41%) developed complications; the most common was pouchitis, which occurred in 18 patients with ulcerative colitis. Forty-two children underwent reoperation; 38 had ulcerative colitis. There were no deaths. Six children (5.2%) (3 with Crohn disease) required a permanent ileostomy. Six straight pull-throughs were converted to J-pouches because of stool frequency; 19 patients with lateral pouches underwent pouch reconstruction or spout resection because of stasis. With a mean follow-up of 7.1 years, 107 children (92.2%) were progressing well.


CONCLUSIONS
Ulcerative colitis is a more severe disease in children. The ileoanal pull-through procedure is the preferred operation for children with ulcerative colitis, polyposis coli, and selected patients with Hirschsprung disease. The J-pouch is preferred because of simplicity of construction and scarcity of complications.
Fonkalsrud
E W
EW
Division of Pediatric Surgery, University of California, Los Angeles School of Medicine, USA.
D011125:Adenomatous Polyposis Coli / Q000601:surgery*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003082:Colectomy / Q000009:adverse effects / Q000379:methods; D003093:Colitis, Ulcerative / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006627:Hirschsprung Disease / Q000601:surgery*; D006801:Humans; D007081:Ileostomy; D008297:Male; D016737:Proctocolectomy, Restorative / Q000009:adverse effects / Q000379:methods; D012086:Reoperation; D016896:Treatment Outcome