title: [The effect of moxibustion on gastric mucosa in rats and its relation to copper, zinc contents in serum].
abstract: 18 rats were randomly deivided into 3 groups: control grup, the group merely with experimental gastric ulcer and the group with experimental gastric ulcer after 3-week moxibustion. The results showed: (1) moxibustion could significantly reduce the ulcer area of the rats (P < 0.05); (2) compared with control group, the experimental gastric ulcer model rats had an increase in copper content and Cu/Zu ratio, the differences were statistically significant (P < 0.05, P < 0.01); (3) in contrast to the rats merely with experimental gastric ulcer, moxibustion-pretreated rats had a significant increase in Zinc content in serum (P < 0.01), but its copper content and Cu/Zn ratio in serum were significantly decreased (P < 0.05, P < 0.01). The results confirmed that moxibustion pretreatment at "Shen-Jue" could protect the gastric mucosa from strass-induced ulcer, having protective effect on gastric mucosa. The results also suggested that there was a disbalance in trace elements metabolism, but moxibustion could improve it. This was most likely to be one of the mechanisms of moxibustion protection on gastric mucosa.
authors.affiliation: Dept. of Physiology, Zhenjiang Medical College.
authors.forename: M
authors.initials: M
authors.lastname: Chen
authors.forename: N
authors.initials: N
authors.lastname: Cheng
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
authors.forename: R
authors.initials: R
authors.lastname: Zhong
authors.forename: C
authors.initials: C
authors.lastname: Ren
mesh_terms: D000818:Animals; D003300:Copper / Q000097:blood*; D005753:Gastric Mucosa / Q000473:pathology*; D008297:Male; D009071:Moxibustion; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013276:Stomach Ulcer / Q000097:blood / Q000473:pathology / Q000628:therapy*; D015032:Zinc / Q000097:blood*
chemical_list: D003300:Copper; D015032:Zinc