Clinical and serological courses of a newborn with post-transfusion hepatitis C.
The clinical and serological course of a haemophilic baby who was transfused with 160 ml of blood containing the hepatitis C virus (HCV) (0.70 Meq. ml-1) on the sixth-post-natal day is described. He is the infant of an HCV-negative mother. One month after the transfusion, there was a marked increase in HCV RNA and a small amount of HCV antibody was detected. This case provides evidence that a newborn is capable of producing HCV antibodies.
Maniwa
H
H
Department of Pediatrics, Nagoya City University Medical School, Japan.
Miyake
Y
Y
Hamada
M
M
Oda
T
T
Li
R
R
Yokoyama
T
T
Sugiyama
K
K
Wada
Y
Y
D004279:DNA, Viral / Q000032:analysis; D016174:Hepacivirus / Q000737:chemistry; D006526:Hepatitis C / Q000150:complications*; D018937:Hepatitis C Antibodies / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D065227:Transfusion Reaction
D004279:DNA, Viral; D018937:Hepatitis C Antibodies