title: Changes of morphological, biological and antigenic properties of avian influenza A virus haemagglutinin H2 in the course of adaptation to new host.
abstract: The alterations of avian influenza A virus haemagglutinin (HA) H2 as a result of adaptation to mice were first investigated in this study. HA of mouse-adapted (MA) variant was somewhat different from that of the original strain in electrophoretical mobility, antigenic structure and in haemagglutination activity with mouse red blood cells.
authors.affiliation: D.I. Ivanovsky Institute of Virology, Russian Academy of Medical Sciences, Moscow, Russia.
authors.forename: A S
authors.initials: AS
authors.lastname: Lipatov
authors.forename: A K
authors.initials: AK
authors.lastname: Gitelman
authors.forename: E A
authors.initials: EA
authors.lastname: Govorkova
authors.lastname: Smirnov YuA
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001717:Birds; D002460:Cell Line; D002642:Chick Embryo; D004285:Dogs; D004591:Electrophoresis, Polyacrylamide Gel; D004912:Erythrocytes / Q000276:immunology; D006386:Hemagglutination Tests; D019267:Hemagglutinin Glycoproteins, Influenza Virus; D006389:Hemagglutinins, Viral / Q000737:chemistry / Q000276:immunology*; D009980:Influenza A virus / Q000276:immunology*; D005585:Influenza in Birds / Q000276:immunology / Q000821:virology; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000276:immunology / Q000821:virology*
chemical_list: D019267:Hemagglutinin Glycoproteins, Influenza Virus; D006389:Hemagglutinins, Viral