Meiosis: how could it work?
A physical connection between homologs is required for reductional segregation at the first division of meiosis. This connection is usually provided by one or a few well-spaced crossovers. A speculative overview of processes leading to formation of these crossovers is presented.
Kleckner
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Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
D000818:Animals; D005075:Biological Evolution; D002453:Cell Cycle; D002875:Chromosomes / Q000502:physiology* / Q000648:ultrastructure; D003434:Crossing Over, Genetic; D006801:Humans; D008540:Meiosis; D008938:Mitosis; D010944:Plants; D011418:Prophase; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae; D013573:Synaptonemal Complex / Q000502:physiology