title: Distinctive serial magnetic resonance changes in a young woman with rapidly evolved neurocysticercosis, with positron emission tomography results.
abstract: A woman aged 21 years noticed numbness of the left hand, dysarthria, and right hemiparesis. Magnetic resonance imaging (MRI) showed homogeneously enhanced lesions in the bilateral cerebral white matter; these enlarged within 2 weeks, showing ring-like enhancement, and then spontaneously decreased in size and enhancement. Neurocysticercosis was confirmed by repeated, significantly positive serology results and the dramatic response to praziquantel. Subsequently, positron emission tomography (PET) revealed persisting regions of possibly decreased cerebral uptake of [18F]2-fluoro-2-deoxyglucose. This is the first documentation of such distinctive serial MRI changes and the results of PET in neurocysticercosis.
authors.affiliation: Department of Neurology, Tokai University School of Medicine, Kanagawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Nagayama
authors.forename: Y
authors.initials: Y
authors.lastname: Shinohara
authors.forename: K
authors.initials: K
authors.lastname: Nagakura
authors.forename: Y
authors.initials: Y
authors.lastname: Izumi
authors.forename: S
authors.initials: S
authors.lastname: Takagi
mesh_terms: D000328:Adult; D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use; D001921:Brain / Q000378:metabolism; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000469:parasitology*; D003551:Cysticercosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003847:Deoxyglucose / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D005260:Female; D005462:Fluorine Radioisotopes / Q000493:pharmacokinetics; D019788:Fluorodeoxyglucose F18; D006225:Hand; D006429:Hemiplegia / Q000469:parasitology; D006801:Humans; D008279:Magnetic Resonance Imaging; D011223:Praziquantel / Q000627:therapeutic use; D012678:Sensation Disorders / Q000469:parasitology; D014055:Tomography, Emission-Computed
chemical_list: D000980:Antiplatyhelmintic Agents; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D011223:Praziquantel; D003847:Deoxyglucose