Reactive and degenerative changes of tissues surrounding a brain tumor.
We report here immunohistochemical and ultrastructural studies of the pattern of brain degeneration being a consequence of the presence of brain tumors. Robust microglial reaction with upregulation of MHC II type antigens within and around the brain tumor were seen along with the purely degenerative phenomena like neuroaxonal dystrophy (NAD) and myelin dilatation ("ballooning"). The reaction was monotonous and independent of the histological type of the brain tumor.
Majchrowska
A
A
Electron Microscopy Laboratory, Department of Oncology, School of Medicine, Lódź.
Barcikowska
M
M
Alwasiak
J
J
Liberski
P P
PP
D001284:Atrophy / Q000503:physiopathology*; D001932:Brain Neoplasms / Q000503:physiopathology* / Q000648:ultrastructure*; D046508:Culture Techniques; D006801:Humans; D007150:Immunohistochemistry; D009186:Myelin Sheath / Q000648:ultrastructure; D009410:Nerve Degeneration