[The vasopressin- and oxytocinergic systems of rat strains selected for their capacity to acquire active avoidance].
Vasopressin- and oxytocinergic structures of the hypothalamus were stained immunochemically. Volume of the nucleoli of the neurosecretory cells in the paraventricular, supraoptic and anterior commissural nuclei was calculated as a measure of neurohormone synthesis. The amount of the neurosecretory material in the neurohaemal organs (external median eminence and posterior pituitary) was estimated cytophotometrically. It was shown that both synthesis and secretion of the neurohormones were higher in intact KLA rats as compared to KHA rats. In three days after inescapable electroshock opposite changes in synthesis and secretion of both oxytocin and vasopressin were revealed: a rise in KHA rats and a fall down in KLA ones. It is suggested that differences between KHA and KLA rats in the reaction of vasopressin- and oxytocinergic systems to stress is due to different strategy of rats behavior at electroshock.
Chernigovskaia
E V
EV
Zhukov
D A
DA
Danilova
O A
OA
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D002466:Cell Nucleolus / Q000502:physiology / Q000648:ultrastructure; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D007031:Hypothalamus / Q000502:physiology / Q000648:ultrastructure; D007150:Immunohistochemistry; D008297:Male; D009490:Neurosecretory Systems / Q000502:physiology / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains / Q000502:physiology*; D018045:Receptors, Oxytocin / Q000502:physiology*; D017483:Receptors, Vasopressin / Q000502:physiology*; D012641:Selection, Genetic; D012769:Shock / Q000503:physiopathology
D018045:Receptors, Oxytocin; D017483:Receptors, Vasopressin
Vazopressin- i oksitotsinergicheskie sistemy u liniĭ krys, selektirovannykh po sposobnosti k vyrabotke aktivnogo izbeganiia.