title: [Multicentricity in renal adenocarcinoma: its incidence and the therapeutic implications].
abstract: Unsuspected multicentricity in single Renal Adenocarcinoma (RAC) together with the prospects of incomplete neoplasia removal are the 2 major disadvantages for the acceptance of traditional renal surgery in birenal carriers of medium size, low grade single RAC. This paper is a retrospective review of our series of RAC patients who underwent radical nephrectomy between January 1986 and October 1994 with the following purpose: 1) To evaluate our incidence of unsuspected multicentricity. 2) To evaluate the characteristics of such multicentricity. 3) To evaluate, in the assumption that traditional surgery had been indicated for patients with small size RAC, in how many patients tumoral resection would have been incomplete due to existence of satellite tumoral nodes in the preserved renal parenchyma. Of 110 patients undergoing radical nephrectomy, 11.8% (13/110) had unsuspected multicentricity. In 10 patients there was multiple satellite nodes with size ranging from 0.3 to 3 cm. We conclude that there is not relationship between multicentricity and size or stage of primary tumour and that, by applying strict criteria (size, location, well defined tumoral wall and form of presentation) to select the patients who can be candidates to traditional renal surgery, the probability to perform it in patients with multicentric RAC would be considerably reduced.
authors.affiliation: Servicio de Urología, H.G.U. Gregorio Marañón, Universidad Complutense, Madrid.
authors.forename: F
authors.initials: F
authors.lastname: Herranz Amo
authors.forename: J M
authors.initials: JM
authors.lastname: Diez Cordero
authors.forename: F
authors.initials: F
authors.lastname: Verdú Tartajo
authors.forename: D
authors.initials: D
authors.lastname: Diez Nau
authors.forename: J J
authors.initials: JJ
authors.lastname: Rascón
authors.forename: I
authors.initials: I
authors.lastname: Moncada Iribarren
authors.forename: E
authors.initials: E
authors.lastname: Lledó García
authors.forename: F
authors.initials: F
authors.lastname: González Chamorro
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez Fernández
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D015994:Incidence; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009392:Nephrectomy; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology
vernacular_title: Multicentricidad en el adenocarcinoma renal: incidencia e implicaciones terapéuticas.