title: Goodpasture's disease and Alport's syndromes.
abstract: Goodpasture's, or anti-glomerular basement membrane, disease is an uncommon, usually severe disease caused by autoimmunity to a component of certain basement membranes. Alport's syndrome is an inherited, degenerative disorder that affects specific basement membranes. The two are linked by the involvement of type-IV collagen (basement membrane collagen) in their pathogenesis.
authors.affiliation: Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill, Scotland, United Kingdom.
authors.forename: A N
authors.initials: AN
authors.lastname: Turner
authors.forename: A J
authors.initials: AJ
authors.lastname: Rees
mesh_terms: D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001485:Basement Membrane / Q000473:pathology; D003094:Collagen / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D016030:Kidney Transplantation / Q000473:pathology; D008854:Microscopy, Electron; D009394:Nephritis, Hereditary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011379:Prognosis
chemical_list: D003094:Collagen