title: Propofol permits tracheal intubation but does not affect postoperative myalgias.
abstract: OBJECTIVE
  To determine the effect of propofol without succinylcholine on intubating conditions and postoperative myalgias in ambulatory surgical patients undergoing general anesthesia.
  
  
  METHODS
  Prospective, double-blind, randomized study.
  
  
  METHODS
  Ambulatory surgery adult patients.
  
  
  METHODS
  56 ASA physical status I and II adult patients undergoing general endotracheal anesthesia.
  
  
  METHODS
  Group 1 patients received thiamylal plus succinylcholine, Group 2 patients received propofol plus succinylcholine; and Group 3 patients received propofol plus saline. All patients received fentanyl, lidocaine, and nitrous oxide plus isoflurane in oxygen.
  
  
  RESULTS
  Incidence and severity of fasciculations, tracheal intubating conditions, and myalgias on the first and third postoperative days were measured. Propofol did not affect the incidence or severity of fasciculations following succinylcholine, or the incidence of myalgias. Of patients who received propofol without succinylcholine, intubation was successful in 85%.
  
  
  CONCLUSIONS
  Propofol did not affect the incidence or severity of postoperative myalgias following succinylcholine.
authors.affiliation: Department of Anesthesiology, Mount Sinai School of Medicine, New York, New York, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Mingus
authors.forename: A K
authors.initials: AK
authors.lastname: Shamsi
authors.forename: J F
authors.initials: JF
authors.lastname: Recant
authors.forename: J B
authors.initials: JB
authors.lastname: Eisenkraft
mesh_terms: D000328:Adult; D000556:Ambulatory Surgical Procedures; D018686:Anesthetics, Intravenous; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D009135:Muscular Diseases / Q000517:prevention & control*; D009467:Neuromuscular Depolarizing Agents / Q000627:therapeutic use; D010149:Postoperative Pain / Q000517:prevention & control*; D015742:Propofol; D011446:Prospective Studies; D013390:Succinylcholine / Q000627:therapeutic use
chemical_list: D018686:Anesthetics, Intravenous; D009467:Neuromuscular Depolarizing Agents; D013390:Succinylcholine; D015742:Propofol