[Amplified fragment length polymorphism of the VNTR locus COL2A1 in Chinese population].
The amplifiable VNTR polymorphic system COL2A1 has been investigated in a Chinese Han population (n = 120) by the polymerase chain reaction (PCR) and PAGE horizontal electrophoresis followed by silver stain. In order to accurately identify COL2A1 alleles, a number of human allele ladders prepared by mixing DNAs extracted from different individuals of known COL2A1 genotypes were used. A total of 14 different alleles in 23 genotypes were observed in this Chinese Han population. Among them, four were new alleles disclosed in the present study. The results imply that COL2A1 locus may be served as a genetic marker in forensic haemogenetics as well as in anthropogenetics.
Hou
Y
Y
Department of Forensic Serology, West China University of Medical Sciences, Chengdu.
Gou
Q
Q
Wu
M
M
D001483:Base Sequence; D002681:China / Q000208:ethnology; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid