Cutaneous T-cell lymphoma associated with granulomatous slack skin.
Granulomatous slack skin disease (GSS) is a rare disorder characterized by bulky cutaneous lesions and epithelioid and giant cell granulomas with destruction of the dermal elastic tissue. We detail the observation of a 29-year-old man with clinical and histological features of GSS. Pendulous skin tumors were associated with typical clinical and immunohistochemical aspects of mycosis fungoides and with clonal rearrangement of the V gamma T-cell receptor gene in lesional skin. This case report supports cutaneous T-cell lymphoma as a cause of GSS.
Mouly
F
F
Department of Dermatology, Saint Louis Hospital, Paris, France.
Baccard
M
M
Cayuela
J M
JM
Janssen
F
F
Verola
O
O
Flageul
B
B
Morel
P
P
D000328:Adult; D006099:Granuloma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications* / Q000175:diagnosis; D008297:Male; D009182:Mycosis Fungoides / Q000150:complications / Q000175:diagnosis; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology*; D012878:Skin Neoplasms / Q000150:complications* / Q000175:diagnosis