title: [Anomalous origin of the left coronary artery from the pulmonary trunk with myocardial infarction and severe left ventricular dysfunction in infancy--assessment of myocardial damage using SPECT studies with 201TlCl and 123I-BMIPP].
abstract: A 4-month-old male infant with Bland-White-Garland (BWG) syndrome complicated myocardial infarction was reported. Signs included tachypnea, coughing, and failure to thrive. However, there was no sign of myocardial infarction. A chest radiograph revealed cardiomegaly (CTR = 65%) and electrocardiogram showed abnormal Q waves in I, aVL, V6 leads. Cardiac catheterization and angiography revealed marked dilatation of left ventricle (end-diastolic volume = 384 ml/m2) and extremely depressed ejection fraction (16%), confirming the diagnosis of BWG syndrome. A 201TlCl-myocardial SPECT demonstrated apical defect and hypoperfusion in the anterolateral, inferoposterior walls, whereas 123I-beta-methyl-p-iodophenylpentadecanoic-acid (123I-BMIPP) SPECT showed a wider defect area. SPECT studies with 201TlCl and 123I-BMIPP, are useful to assess myocardial viability more accurately in BWG syndrome.
authors.affiliation: Department of Pediatrics, University of Tsukuba, Ibaragi, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyamoto
authors.forename: H
authors.initials: H
authors.lastname: Horigome
authors.forename: H
authors.initials: H
authors.lastname: Sato
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Inai
authors.forename: T
authors.initials: T
authors.lastname: Takeda
authors.forename: N
authors.initials: N
authors.lastname: Ishikawa
authors.forename: H
authors.initials: H
authors.lastname: Hoshino
authors.forename: Y
authors.initials: Y
authors.lastname: Itai
mesh_terms: D003330:Coronary Vessel Anomalies / Q000150:complications / Q000000981:diagnostic imaging*; D005227:Fatty Acids; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000000981:diagnostic imaging*; D011651:Pulmonary Artery / Q000002:abnormalities*; D013577:Syndrome; D013793:Thallium; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000000981:diagnostic imaging*
chemical_list: D005227:Fatty Acids; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D013794:Thallium Radioisotopes; C049338:iodofiltic acid; C027549:thallium chloride; D013793:Thallium