title: Gadolinium-DTPA enhanced echoplanar MR imaging of the liver: preliminary observations.
abstract: This study describes our preliminary experience with dynamic gadopentetate dimeglumine enhanced echoplaner MR imaging (EPI) in fifteen patients with focal liver lesions. Lesion diagnosis was established by histology (n = 3) or typical imaging characteristics (exclusive of the EPI study) combined with clinical follow up (n = 12). Dynamic gadopentetate dimeglumine (0.1 mmol/kg) enhanced MR imaging was performed on a commercially available 1.5 T EPI equipped MR system using a single-excitation fat-suppressed inversion recovery pulse sequence. The choice of an IR sequence allowed nulling of the lesion signal by varying T1 prior to enhancement creating the optimal conditions for qualitative inspection of the enhancement profile. Intershot delay (defined as TR) ranged from 1-5s. Image analysis was performed qualitatively by two radiologists. Benign and malignant lesions displayed temporal enhancement profiles compatible with characteristic findings expected with conventional imaging modalities. Further refinements in our technique and expanded system capabilities will allow dynamic imaging of the entire liver with improved temporal resolution over conventional sequences.
authors: Department of Radiology, Massachusetts General Hospital, Boston 02114, USA.
authors: D A
authors: DA
authors: Gervais
authors: S
authors: S
authors: Saini
authors: P F
authors: PF
authors: Hahn
authors: P
authors: P
authors: Reimer
authors: M A
authors: MA
authors: Goldberg
authors: R
authors: R
authors: Weiskoff
mesh_terms: D003287:Contrast Media; D017352:Echo-Planar Imaging / Q000379:methods*; D019786:Gadolinium DTPA; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA