An open study of mupirocin in Libyan patients with skin infections.
In an open study in Libya 48 patients suffering from skin infections, usually caused by staphylococci and streptococci, were treated with a new topical antibiotic, mupirocin, applied three times daily for 7 days. By day 7 of treatment 93.5% of patients were asymptomatic and were considered cured, and 100% were considered cured 1 week later. In total, 50 bacterial strains were isolated, of which, 86% were staphylococci and 14% were streptococci. Neither adverse events nor cutaneous reactions were reported. Mupirocin 2% ointment proved to be effective and safe in the treatment of primary and secondary skin infections.
El Ferghani
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Department of Dermatology, Central Hospital, Tripoli, Libya.
D000287:Administration, Topical; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D004926:Escherichia coli; D005260:Female; D006801:Humans; D008002:Libya; D008297:Male; D008826:Microbial Sensitivity Tests; D016712:Mupirocin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D009824:Ointments; D017192:Skin Diseases, Bacterial / Q000188:drug therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus; D013290:Streptococcal Infections / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D009824:Ointments; D016712:Mupirocin