Indocyanine green angiography in the juvenile haemorrhagic choroidopathy.
Juvenile haemorrhagic choroidopathy (JHC) is an idiopathic syndrome marked by macular choroidal neovascularization (CNV) in patients under the age of 50. We used fluorescein angiography (FA) and indocyanine green angiography (ICGA) to examine 17 patients with macular CNV and JHC. CNV was always unilateral. On ICGA examination the CNV were weakly fluorescent in 59% of cases, hyperfluorescent in the remaining 41%. ICGA showed up the following alterations: a) areas with diffuse choroidal hyperfluorescence at the posterior pole or in the peripapillary region in 11 affected eyes (65%), in the fellow eye too in 5 patients; b) areas of choroidal hypofluorescence at the posterior pole but also outside the vascular arcades in 2 affected eyes (12%). In conclusion, ICGA does not appear indispensable for detecting CNV in JHC but this method does show up diffuse choroidal alterations not detectable with FA. The pathogenetic implications of the ICGA findings are discussed.
Pece
A
A
Department of Ophthalmology and Visual Sciences, Scientific Institute HS. Raffaele, University of Milano, Italy.
Avanza
P
P
Introini
U
U
Bolognesi
G
G
Brancato
R
R
D000293:Adolescent; D000328:Adult; D002829:Choroid / Q000098:blood supply; D002832:Choroid Hemorrhage / Q000473:pathology*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000473:pathology
D004396:Coloring Agents; D007208:Indocyanine Green