Cost-effectiveness of hypertension treatment.
The benefits of antihypertensive treatment are influenced by both the absolute initial cardiovascular risk, and the relative reduction. Because age is a major determinant of the absolute cardiovascular risk, and because the strategies for hypertension diagnosis and treatment are not very much influenced by age, hypertension management appears to be more cost-effective after the age of 45, in both men and women. Below this age, the absolute gain in life-years seems to be smaller, and sensitivity analysis demonstrate an important influence on the results of assumptions about the effects of treatment on quality of life and the discounting rate.
Ménard
J
J
Centre de Médecine Préventive Cardiovasculaire, Hôpital Broussais, Paris, France.
D000328:Adult; D000367:Age Factors; D000959:Antihypertensive Agents / Q000191:economics* / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000517:prevention & control; D003362:Cost-Benefit Analysis; D005260:Female; D017048:Health Care Costs; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy* / Q000191:economics*; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D011788:Quality of Life; D012307:Risk Factors; D016896:Treatment Outcome
D000959:Antihypertensive Agents