Successful localization of an occult ACTH-secreting bronchial carcinoid tumour with 111indium-DTPA labelled octreotide.
Ectopic ACTH secretion due to occult carcinoid tumours is an occasional cause of ACTH dependent Cushing's syndrome. In many cases the ectopic source may be obvious, but sometimes no obvious source is evident, the so-called occult ectopic syndrome. Due to their small size, localization of such occult tumours, particularly bronchial carcinoids, may be extremely difficult. Whole body CT and venous sampling studies have been used but are not always successful in determining the site of such lesions. We report a 40-year-old patient with the ectopic ACTH syndrome due to a 0.6-cm bronchial carcinoid tumour which was successfully localized by 111indium-DTPA labelled octreotide scintigraphy.
Tsagarakis
S
S
Department of Endocrinology, Evangelismos Hospital, Athens, Greece.
Giannakenas
C
C
Vassilakos
P J
PJ
Platis
O
O
Belenis
I
I
Kaskarelis
J
J
Rontoyianni
D
D
Thalassinos
N
N
D000182:ACTH Syndrome, Ectopic / Q000000981:diagnostic imaging*; D000328:Adult; D001984:Bronchial Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging* / Q000378:metabolism; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging* / Q000378:metabolism; D015282:Octreotide; D004369:Pentetic Acid; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed
D007205:Indium Radioisotopes; D004369:Pentetic Acid; D015282:Octreotide