Molecular cloning of a third chitinase gene (CHT1) from Candida albicans.
Here we report the complete nucleotide sequence of a third chitinase gene (CHT1) from the dimorphic human pathogen Candida albicans. The deduced amino acid (aa) sequence of Cht1 consists of 416 aa and displays 36% protein sequence similarity to chitinases Cht2 and Cht3, from C. albicans. Interestingly the domain structure of Cht1 is truncated when compared to the other chitinases of C. albicans and lacks a Ser/Thr-rich region.
McCreath
K J
KJ
Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139, USA.
Specht
C A
CA
Liu
Y
Y
Robbins
P W
PW
D000595:Amino Acid Sequence; D001483:Base Sequence; D002176:Candida albicans / Q000201:enzymology / Q000235:genetics*; D002688:Chitinases / Q000737:chemistry / Q000235:genetics*; D003001:Cloning, Molecular; D005656:Fungal Proteins; D005800:Genes, Fungal / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
D005656:Fungal Proteins; D002688:Chitinases; C101191:Cht1 protein, Candida albicans