Lithium-induced akathisia responds to low-dose mianserin: case report.
A case of acute akathisia induced by lithium treatment is described. Since lithium administration leads to activation of serotonergic neurotransmission, the 5-HT2A/2C and 5-HT3 antagonist mianserin was added as a possible anti-akathitic agent. Mianserin treatment (15 mg/day at 21.00 h) resulted in amelioration of the lithium-induced akathisia.
Poyurovsky
M
M
Tirat Carmel Mental Health Center, Haifa, Tel Aviv University, Israel.
Kreinin
A
A
Modai
I
I
Weizman
A
A
D000328:Adult; D017109:Akathisia, Drug-Induced / Q000188:drug therapy*; D005500:Follow-Up Studies; D006801:Humans; D008094:Lithium / Q000009:adverse effects*; D008297:Male; D008803:Mianserin / Q000627:therapeutic use*; D016896:Treatment Outcome
D008803:Mianserin; D008094:Lithium