Positron emission tomography of in-vivo binding characteristics of atypical antipsychotic drugs. Review of D2 and 5-HT2 receptor occupancy studies and clinical response.
Nyberg
S
S
Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden.
Nakashima
Y
Y
Nordström
A L
AL
Halldin
C
C
Farde
L
L
D014150:Antipsychotic Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging* / Q000187:drug effects; D003024:Clozapine / Q000493:pharmacokinetics / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D006801:Humans; D017448:Receptors, Dopamine D2 / Q000378:metabolism*; D011985:Receptors, Serotonin / Q000145:classification / Q000378:metabolism*; D018967:Risperidone / Q000493:pharmacokinetics / Q000627:therapeutic use; D012559:Schizophrenia / Q000000981:diagnostic imaging / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D014055:Tomography, Emission-Computed
D014150:Antipsychotic Agents; D017448:Receptors, Dopamine D2; D011985:Receptors, Serotonin; D003024:Clozapine; D018967:Risperidone