[Detection and significance of HCV RNA in saliva, seminal fluid and vaginal discharge in patients with hepatitis C].
To investigate the transmission of HCV infection through family contact, we detected HCV RNS in body fluids (saliva, seminal and vaginal discharge) of 16 serum HCV RNA positive patients (including 7 men and 9 women) and in sera of their family members. The positive rates of HCV RNA in the body fluids were 31.25% (5/16) in saliva, 57.14% (4/17) in seminal fluid and 22.22% (2/9) in vaginal discharge, respectively. Among the family members in our series, all were negative for both anti-HCV and HCV RNA, despite two spouses positive for HCV RNA. This result strongly suggested the potential possibility of the transmission of HCV infection through the family contact.
Tang
Z
Z
Abteilung für klinische Immunologie.
Yang
D
D
Hao
L
L
Tang
Z
Z
Huang
Y
Y
Wang
S
S
D000328:Adult; D005260:Female; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000635:transmission*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000032:analysis*; D012463:Saliva / Q000821:virology; D012661:Semen / Q000821:virology; D014626:Vaginal Smears
D012367:RNA, Viral
Nachweis und Bedeutung von HCV RNS im Speichel, Sperma und Vaginalsekret von Patienten mit Hepatitis C.