Rapid cycling bipolar affective disorder and familial learning disability associated with temporal lobe (occipitotemporal gyrus) cortical dysplasia.
This case report describes a hitherto unreported association between temporal cortical dysplasia and rapid cycling bipolar affective disorder in a learning disabled young man with a family history of rapid cycling bipolar affective disorder in two dysmorphic and learning disabled maternal uncles, and probably learning disability in the mother and grandmother. An identical family with similar findings could not be located in the English literature.
Raghavan
R
R
Department of Neuropathology, Newcastle General Hospital, Newcastle upon Tyne, England.
Day
K A
KA
Perry
R H
RH
D000328:Adult; D001714:Bipolar Disorder / Q000235:genetics* / Q000473:pathology / Q000523:psychology; D006801:Humans; D007124:Immunoenzyme Techniques; D007326:Institutionalization; D008607:Intellectual Disability / Q000235:genetics* / Q000473:pathology / Q000523:psychology; D007360:Intelligence / Q000235:genetics; D007859:Learning Disabilities / Q000235:genetics* / Q000473:pathology / Q000523:psychology; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000235:genetics* / Q000473:pathology / Q000523:psychology; D009474:Neurons / Q000473:pathology; D010375:Pedigree; D013702:Temporal Lobe / Q000002:abnormalities* / Q000473:pathology