title: Biomechanical studies of transthoracic vertebral body replacement with autologous bone grafts (fibula and rib).
abstract: Thoracic processes which destroy vertebral bodies leave gaps which usually have to be bridged. The aim of our experiments was to find out whether rib and fibula grafts are suitable vertebral body substitutes from the biomechanical point of view. Therefore, we examined characteristics of vertebral body/bone graft/vertebral body arrangements under the influence of pulsating compression forces in a testing machine. The deformation of the rib graft alone was 0.78 mm under a preselected peak load of 1010 Newton. When the rib graft was placed between two vertebral bodies, the deformation (creeping) was 6 mm under a peak load of 1010 Newton. The deformation of the fibula graft alone was 0.41 mm, and when placed between vertebral bodies maximally 3 mm. The results of our experiments lead to the conclusion that ribs modified according to our design are prinzipally suitable for vertebral body replacement in the thoracic region as far as primary stress resistance is concerned. Characteristics of these bone grafts in the human body are being followed-up.
authors: Institute for Forensic Medicine, University of Bonn, Germany.
authors: B
authors: B
authors: Kaden
authors: W
authors: W
authors: Koch
authors: K
authors: K
authors: Varchmin-Schultheiss
authors: M
authors: M
authors: Wunsch
authors: G
authors: G
authors: Fuhrmann
mesh_terms: D001696:Biomechanical Phenomena; D016025:Bone Transplantation / Q000502:physiology*; D006801:Humans; D013718:Tensile Strength; D013904:Thoracic Vertebrae / Q000503:physiopathology / Q000601:surgery*; D014182:Transplantation, Autologous; D016474:Weight-Bearing / Q000502:physiology*