Acute cerebellar edema following intra-arterial tissue plasminogen activator thrombolysis for basilar artery occlusion--case report.
A 61-year-old male developed acute cerebellar swelling after thrombolytic therapy for basilar artery occlusion. He was treated with intra-arterial tissue plasminogen activator 12 hours following symptomatic onset, and did well in the immediate post-treatment period but deteriorated the next day. Computed tomography demonstrated acute cerebellar edema and hydrocephalus. Suboccipital external decompression and ventricular drainage were performed. He survived and 1 year later he could perform daily activities at home. Computed tomography and angiography are essential to monitor the post-treatment course following thrombolysis of vertebrobasilar occlusive disease.
Matsumoto
K
K
Department of Neurosurgery, Hanwa Memorial Hospital, Osaka.
Kato
A
A
Kohmura
E
E
Fujinaka
T
T
Fukuhara
R
R
D000208:Acute Disease; D001157:Arterial Occlusive Diseases / Q000503:physiopathology / Q000601:surgery*; D001488:Basilar Artery / Q000503:physiopathology / Q000601:surgery*; D001933:Brain Stem / Q000503:physiopathology; D002531:Cerebellum / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000503:physiopathology; D004487:Edema / Q000209:etiology* / Q000503:physiopathology*; D006801:Humans; D006849:Hydrocephalus / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
D010959:Tissue Plasminogen Activator