Pericardial angiosarcoma after mediastinal irradiation for seminoma. A case report and a review of the literature.
BACKGROUND
Second malignancies are a well recognized complication of radiation therapy.


METHODS
We performed a computer search of the literature using the Medline Database for Pericardial Tumors and Post-Irradiation Sarcomas.


RESULTS
The case history of a patient who developed a radiation-induced pericardial angiosarcoma is described. We present a detailed review of pericardial sarcomas.


CONCLUSIONS
We believe this to be the first report of a radiation-induced pericardial sarcoma. The importance of continued long-term observation for patients who receive mediastinal irradiation is stressed.
Killion
M J
MJ
Department of Medicine, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA.
Brodovsky
H S
HS
Schwarting
R
R
D006394:Hemangiosarcoma / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum / Q000528:radiation effects*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology*; D010496:Pericardium / Q000473:pathology* / Q000528:radiation effects*; D018239:Seminoma / Q000473:pathology / Q000532:radiotherapy*; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery