Synaptic relations of neurotensinergic neurons in the dorsal raphe nucleus.
The ultrastructure and synaptic relations of neurotensinergic neurons in the rat dorsal raphe nucleus (DRN) were examined. The neurotensin-like immunoreactive (NT-L1) neurons in the DRN were fusiform or spherical. The NT-LI perikarya could only be detected in colchicine-treated animals whereas the immunoreactive axon terminals could only be found in the animals not treated with colchicine. Although many NT-LI dendrites received synapses from nonimmunoreactive axon terminals, the NT-LI perikarya received few synapses. NT-LI axon terminals also made synapses on nonimmunoreactive dendrites. Occasionally, synapses were found between the NT-LI axon terminals and NT-LI dendrites in the cases in which the animals were not treated with colchicine.
Wang
Q P
QP
Department of Anatomy, Showa University School of Medicine, Tokyo, Japan.
Guan
J L
JL
Nakai
Y
Y
D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D016253:Microscopy, Immunoelectron; D009479:Neuropeptides / Q000502:physiology*; D009496:Neurotensin / Q000502:physiology*; D010146:Pain / Q000503:physiopathology; D011903:Raphe Nuclei / Q000502:physiology* / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar; D013569:Synapses / Q000648:ultrastructure*
D009479:Neuropeptides; C031644:neurotensin-like immunoreactivity; D009496:Neurotensin