title: Fulminant Guillain-Barré syndrome with quadriplegia and total paresis of motor cranial nerves as a result of segmental demyelination.
abstract: Guillain-Barré syndrome (GBS) is a subacute demyelinating polyneuropathy with a monophasic course. Rarely, demyelination may be so severe as to produce electrically unexcitable nerves. We present a patient with fulminant onset of symptoms who was quadriplegic and had bilateral involvement of all motor cranial nerves. Serial EMGs indicated that segmental demyelination was responsible for these clinical findings.
authors: Department of Neurology, Tan Tock Seng Hospital, Singapore.
authors: A K
authors: AK
authors: Tan
authors: M W
authors: MW
authors: Chee
mesh_terms: D003389:Cranial Nerve Diseases / Q000209:etiology*; D003711:Demyelinating Diseases / Q000150:complications*; D004553:Electric Conductivity; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D006801:Humans; D008875:Middle Aged; D010291:Paresis / Q000209:etiology*; D011129:Polyradiculoneuropathy / Q000209:etiology*; D011782:Quadriplegia / Q000209:etiology*