title: Upper airway obstruction caused by acquired inhibitor to factor VIII.
abstract: Bleeding caused by inhibitors to factor VIII is a rare medical emergency requiring immediate specialist investigation and management. Urgent initiation of therapy with high dose factor VIII concentrates may be life saving. Successful management of acute upper airway obstruction from uncontrolled haemorrhage into the oropharyngeal tissues should be achieved with fibreoptic guided nasotracheal intubation.
authors: Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong.
authors: G M
authors: GM
authors: Joynt
authors: N W
authors: NW
authors: Wickham
authors: R J
authors: RJ
authors: Young
authors: C D
authors: CD
authors: Gomersall
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000209:etiology* / Q000628:therapy; D005169:Factor VIII / Q000037:antagonists & inhibitors* / Q000627:therapeutic use; D005260:Female; D005336:Fiber Optic Technology; D006470:Hemorrhage / Q000097:blood / Q000150:complications*; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods; D010608:Pharyngeal Diseases / Q000097:blood / Q000150:complications*
chemical_list: D005169:Factor VIII