[Primary non-Hodgkin's lymphomas of the liver in human immunodeficiency virus infected patients. Three cases].
The occurrence of primary non Hodgkin's lymphoma of the liver has rarely been reported in patients with the human immunodeficiency virus infection. We report 3 cases in these patients, presenting with a single liver tumor in 2 cases and multiple tumors in one case. Diagnosis was made by guided-biopsy. Histologically, there was B diffuse large cell lymphoma in 2 cases, and immunoblastic lymphoma in one case. In one case, RNA of Epstein-Barr virus was found in the nucleus of tumor cells by in situ hybridization. No extrahepatic localization was found in any of the 3 cases. One patient died one week after diagnosis, but the 2 other patients were treated by chemotherapy and were still alive 6 and 30 months later. In patients infected by human immunodeficiency virus, primary non Hodgkin's lymphoma should be investigated in case of liver tumor in order to provide early treatment.
Brugière
O
O
Service des Maladies Infectieuses et Tropicales, Hôpital de l'Institut Pasteur, Paris.
Pialoux
G
G
Carnot
F
F
Pol
S
S
Fournier
S
S
Deslandes
P
P
Trotot
P
P
Dupont
B
B
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000473:pathology / Q000821:virology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D017809:Fatal Outcome; D006566:Herpesviridae Infections / Q000150:complications* / Q000473:pathology / Q000821:virology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000821:virology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000000981:diagnostic imaging; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000150:complications* / Q000473:pathology / Q000821:virology; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D014412:Tumor Virus Infections / Q000150:complications* / Q000473:pathology / Q000821:virology
Lymphomes non hodgkiniens primitifs du foie chez les malades infectés par le virus de l'immunodéficience humaine. Trois cas.