[Effectiveness and innocuousness of the association of calcium dobesilate, dexamethasone acetate and lidocaine versus prednisolone capronate with dibucaine clorohydrate in the treatment of hemorrhoids-].
The objective of the present study was to compare properties of two associations in the topical treatment of hemorrhoids. They were included 40 patient with diagnosis of internal hemorrhoids grade 1 or 2, which was indicated topic treatment after the realization of an interrogatory and anoscopy. The treatment received according to a randomized and double blind design: A = dobesilate of calcium with acetato of dexamethasone and lidocaine or B = Capronato of Prednisolone with Clorhidrato of dibucaina, applied twice a day. They were carried out controls every 7 days. In each control was carried out interrogatory and respective anoscopy. There was a prevalence of the females, and the age corresponded to the 5t decade of the life. Patients of the treatment. A presented greater number of predisponents factors, but minor percentage of previous treatments. As for the evaluation of the punctuation of symptoms and of the grade of Hemorrhoids, comparing beginning and final, they didn't show significant difference interproduct confirming the effectiveness and similar inocuity. In both products was observed a important improvement concerning to the symptoms and grade of hemorrhoids but the patients of the treatment A precipitated the greater speed. As for the evaluation made by the phisicians, the treatment A (88%) and B (85.7%) the got successful outputs. The opinion of the patients was a 100% of marked goods or moderated beneficial. Both treatments were successful so much in effectiveness like in inocuity although the treatment A were always got the best efectiveness outputs.
Marsicano
L J
LJ
Servicio de Gastroenterologia, Hospital Vargas De Caracas.
Pérez
M
M
Urquiola
G
G
D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002123:Calcium Dobesilate / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D003992:Dibucaine / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D006484:Hemorrhoids / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008012:Lidocaine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011239:Prednisolone; D011446:Prospective Studies; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D002123:Calcium Dobesilate; D003907:Dexamethasone; D008012:Lidocaine; D011239:Prednisolone; D003992:Dibucaine
Effectividad e inocuidad de la asociacion de dobesilato de calcio con acetato de dexametasona y lidocaina con capronato de prednisolona con clorhidrato de dibucaina, en el tratamiento de las hemorroides.