[Diagnostic value of C-reactive protein levels in children with bone marrow transplantation].
Serum quantitative C-reactive protein concentrations were measured in 16 bone marrow transplanted children at 202 occasions during and after the transplant period. Serum C-reactive protein concentrations were moderately increased in patients with viral and protozoon infections (5-67 mg/l). High values were measured in patients with bacterial and fungal infections. The C-reactive protein level was between 15-102 mg/l in Coag. neg. Staphylococcus sepsis, and 160-178 mg/l in Pseudomonas aeruginosa infection, when blood cultures were positive. Values of 154-358 mg/l was found with Candida sepsis. C-reactive protein levels were 10-17 mg/l in 7 acute GvHD episodes, only one of the patients had high level (325 mg/l) in GvHD. In these cases the condition was very severe and affected the total surface of the skin and the gastrointestinal tract also. C-reactive protein becomes a valuable aid as laboratory parameter in the diagnosis of bone marrow transplant recipients with suspected bacterial infection and in monitoring of therapeutic efficiency.
Pintér
E
E
Központi Klinikai Laboratórium, Fóvárosi Szent László Kórház, Budapest.
Kriván
G
G
D000293:Adolescent; D016026:Bone Marrow Transplantation; D002097:C-Reactive Protein / Q000378:metabolism*; D002648:Child; D005260:Female; D005334:Fever / Q000097:blood; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity; D018805:Sepsis / Q000097:blood* / Q000382:microbiology
D002097:C-Reactive Protein
A C-reaktív protein meghatározások diagnosztikus értéke csontvelótranszplantált gyermekekben.