Sequence of the nucleocapsid protein gene of subgroup A and B avian pneumoviruses.
The nucleocapsid protein (N) gene of two subgroup A and one subgroup B strains of avian pneumovirus has been cloned and sequenced. The gene of all three isolates comprised 1197 nucleotides (nt), which formed a single major open reading frame, potentially encoding a protein of 391 amino acid residues. The N gene of the two subgroup A isolates differed by only 1 nt but differed by 282 (24%) nt and 35 (11%) amino acids from the B isolate. The predicted protein was identical in length to that of human, bovine and ovine respiratory syncytial viruses, the amino acid identity being approximately 41% overall but with some regions of identity > 90%.
Li
J
J
Institute for Animal Health, Compton Laboratory, Newbury, UK.
Ling
R
R
Randhawa
J S
JS
Shaw
K
K
Davis
P J
PJ
Juhasz
K
K
Pringle
C R
CR
Easton
A J
AJ
Cavanagh
D
D
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002522:Chlorocebus aethiops; D003001:Cloning, Molecular; D004279:DNA, Viral; D008969:Molecular Sequence Data; D019251:Nucleocapsid / Q000235:genetics*; D018111:Pneumovirus / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D017422:Sequence Analysis, DNA; D014422:Turkeys / Q000821:virology; D014709:Vero Cells
D004279:DNA, Viral