Living related liver transplantation. Progress or regress?
The impetus for the development of living related liver programmes lies with donor shortage, which relates inversely to the success of generating cadaveric donors. A shrinking or non-existent cadaveric donor pool leads to an increased death rate among potential recipients awaiting transplantation. The living related liver programmes have by and large been successful, though it is accepted that there is potentially a significant risk to the donors. The technique of live donor liver transplantation is clearly here to stay, but the selection of suitable donors is between the family and the unit. Consequently, because of the lack of international guidelines, the programmes are open to abuse. Steps should be taken to establish either mechanisms of control or a worldwide register to combat this potential.
Talbot
D
D
Liver and Hepatobiliary Unit, Queen Elizabeth Hospital, Queen Elizabeth Medical Centre, Edgbaston, Birmingham, UK.
Buckels
J A
JA
Mayer
A D
AD
D000328:Adult; D002102:Cadaver; D002648:Child; D004992:Ethics, Medical; D005190:Family; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects / Q000191:economics / Q000379:methods; D018579:Patient Selection; D012307:Risk Factors; D014019:Tissue Donors; D009927:Tissue and Organ Procurement; D014850:Waiting Lists