Penicillium species causing onychomycosis.
Onychomycosis caused by mould infection is rare. A 40 year old male patient presented with dystrophic finger nails and multiple, erythematous lesions with slightly raised borders and scaling all over the body. The patient was a known diabetic. He did not respond to griseofulvin. Samples from nails and skin scales were cultured. From the nails, Penicillium species and from the skin scales. Trichophyton rubrum were isolated. Ketoconazole therapy (200 mg twice daily x 4 mths) led to complete cure with negative cultures and normalization of nails.
Ramani
R
R
Dept of Microbiology, Kasturba Medical College, Manipal, Karnataka.
Ramani
A
A
Shivananda
P G
PG
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D048909:Diabetes Complications; D006118:Griseofulvin / Q000627:therapeutic use; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D014009:Onychomycosis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D010407:Penicillium; D014249:Trichophyton
D000935:Antifungal Agents; D006118:Griseofulvin; D007654:Ketoconazole