[Clinical analysis of anaerobic septicemia in 26 patients with extensive burn].
To understand the incidence and importance of anaerobic infection, the aerobic and anaerobic blood culture were carried out simultaneously in 127 patients with extensive burns (TBSA > 50%). Among 39 patients with positive culture, 26 had anaerob growth in blood culture. The total incidence rate of anaerobic septicemia was 20.4%. 61 strains (9 species) of anaerobes were isolated from blood specimens. The predominant anaerobes were Peptococcus (37.7%) and B. fragilis (36.1%). 20 (76.9%) were mixed infection of aerobes and anaerobes. The others thers suffered from combined infection of B. Fragilis and peptococcus combined infection. Finally, 19 patients survived and 7 died (26.9%). The sensitive tests showed that the effective drugs were metronidazot, chloramycin, and lincomycin. These data suggested that the septicemia of extensive burn patients is often caused by anaerobes. Therefore, anaerobe plays an important role in burn infection.
Huang
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X
Department of Burns and Plastic Surgery, Affiliated Xiangya Hospital of Hunan Medical University, Changsha.
Ma
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E
Gong
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L
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology*; D001442:Bacteroides Infections / Q000188:drug therapy*; D001441:Bacteroides fragilis / Q000302:isolation & purification*; D002056:Burns / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D008875:Middle Aged; D010460:Peptococcus / Q000302:isolation & purification*; D011446:Prospective Studies
D000900:Anti-Bacterial Agents; D008795:Metronidazole