title: Rosai-Dorfman disease presenting with multiple orbital and intracranial masses.
abstract: Rosai-Dorfman disease is an idiopathic histocytic proliferative disorder typically characterized by painless cervical adenopathy, fever, and weight loss. Extranodal manifestations are responsible for presentation in approximately 25% of patients. Orbital involvement has been described in about 10% of patients. There have been only 16 reported cases of Rosai-Dorfman disease presenting with an intracranial mass. We report an unusual case of a patient presenting with bilateral orbital tumors as well as multiple intracranial masses. Clinical, magnetic resonance imaging, and histopathological features are discussed.
authors: Department of Neurological Surgery, Presbyterian University Hospital, Pittsburgh, PA 15213-2582, USA.
authors: D K
authors: DK
authors: Resnick
authors: B L
authors: BL
authors: Johnson
authors: T J
authors: TJ
authors: Lovely
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000473:pathology; D002530:Cerebellopontine Angle; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D008297:Male; D009916:Orbital Diseases / Q000473:pathology*