title: Sarcoidosis of the spinal cord with extensive vertebral involvement: a case report.
abstract: We report on a patient with systemic sarcoidosis who was presented with myelopathy and backache. Plain spinal films were normal, CT scan showed sclerotic lesions within the vertebrae. MRI showed more extensive involvement of the spine with multiple vertebral lesions which were hypointense on both T1W1 and T2W1 and did not enhance with gadolinium. MRI also showed high signal lesions within the cervical and lumbar spinal cord on T2-weighted images (T2W1) which were isointense on T1-weighted images (T1W1) and did not enhance. Vertebral biopsy results were consistent with the diagnosis of sarcoidosis. MRI is very sensitive in detecting sarcoidosis of bone but non-specific and other types of sclerotic or lytic bone lesions (notably metastases) need to be excluded.
authors: Department of Neurology, University of Wisconsin Medical School, Madison 53792, USA.
authors: K O
authors: KO
authors: Bushara
authors: G
authors: G
authors: Petermann
authors: A J
authors: AJ
authors: Waclawik
authors: W D
authors: WD
authors: Brown
authors: H S
authors: HS
authors: Schutta
mesh_terms: D000328:Adult; D003287:Contrast Media; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008297:Male; D010026:Osteosclerosis / Q000175:diagnosis / Q000000981:diagnostic imaging; D012507:Sarcoidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013122:Spinal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D005682:Gadolinium