title: Optical breast lesion localization fiber: preclinical testing of a new device.
abstract: Preclinical testing was performed of an optical breast lesion localization fiber to guide surgical excision. The prototype device comprised dual 0.010- inch (0.254-mm)-diameter hooks attached to the tip of a 1,000-microns (0.03937-inch)-diameter optical fiber, which allowed retention in soft tissue after passage through a 17-gauge extra-thin-wall needle. The proximal end of the optical fiber was attached to a 15-mW, 635-nm diode laser, with a thumbscrew connector. The tip of the optical fiber was visible through several centimeters of breast tissue in two human mastectomy specimens, which facilitated determination of the location of the hooks. The optical localization fiber may allow lesions to be approached at surgery by many different paths. Clinical tests are indicated to further evaluate this device.
authors: Department of Diagnostic Radiology, Yale New Haven Hospital, CT 06510, USA.
authors: K L
authors: KL
authors: Hussman
authors: B A
authors: BA
authors: Ward
authors: C F
authors: CF
authors: McKhann
authors: S M
authors: SM
authors: Pustilnick
authors: I
authors: I
authors: Tocino
authors: L J
authors: LJ
authors: Horvath
authors: L E
authors: LE
authors: Philpotts
authors: C H
authors: CH
authors: Lee
mesh_terms: D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D005260:Female; D005336:Fiber Optic Technology / Q000295:instrumentation*; D006801:Humans; D007834:Lasers; D008408:Mastectomy / Q000295:instrumentation*; D055100:Optical Fibers