[Primary lymphomas of bone: a clinicopathologic study of 22 cases].
22 cases of primary lymphoma of bone (PLB) were reported. Multiple bone involvement in two patients, singular bone in twenty patients. One case had regional lymph node involvement. Radiological examination revealed 91% had diffuse lytic lesions. Histological typing was performed according to working formulation. 15 formalin fixed paraffin embedded PLB specimens were studied immunohistochemically by use of the avidin-biotin-peroxide complex (ABC) method to label monoclonal antibodies.


RESULTS
Ten neoplasms were B-cell type, there were T-cell type, the two remaining cases did not express. The ratio of primary lymphomas in this study in extranodal lymphomas is three times that reported in Japan and also higher than that reported in north America in recent years. The proportion of T-cell type is also higher than that reported in Japan. Differential diagnosis and several factors which influence immunostaining were also discussed.
Yang
H
H
Department of Pathology, Third Teaching Hospital, Norman Bethune University of Medical Sciences, Changchun.
Zhao
L
L
Zheng
Z
Z
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged