title: [Severe contact dermatitis caused by mephenesin].
abstract: BACKGROUND
  Mephenesin is a muscle relaxant, mostly applied locally in trauma. It is a component of Traumalgyl cream in association with phenylbutazone. Contact dermatitis due to mephenesin is exceptional.
  
  
  METHODS
  We report here a case of a woman who developed after application of Traumalgyl cream purpuric dermatitis, erythema multiforme-like and urticarial lesions. Patch-tests were strongly positive (+ + +) for both Traumalgyl cream and mephenesin and (+) for phenylbutazone. Improvement of the lesions was observed within 3 weeks.
  
  
  CONCLUSIONS
  Physicians must be aware of the risk of severe contact dermatitis after application of products including mephenesin because of their widely prescription.
authors: Service de Médecine Interne, Hôpital Hôtel-Dieu, Paris.
authors: C
authors: C
authors: Bachmeyer
authors: L
authors: L
authors: Blum
authors: M L
authors: ML
authors: Fléchet
authors: P
authors: P
authors: Duriez
authors: J
authors: J
authors: Cabane
authors: J C
authors: JC
authors: Imbert
mesh_terms: D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology* / Q000473:pathology; D004892:Erythema Multiforme / Q000139:chemically induced; D005260:Female; D006801:Humans; D008615:Mephenesin / Q000009:adverse effects*; D009125:Muscle Relaxants, Central / Q000009:adverse effects*
chemical_list: D009125:Muscle Relaxants, Central; D008615:Mephenesin
vernacular_title: Dermite de contact grave à la méphénésine.