[Iatrogenic drug-induced diseases, requiring hospitalization, in patients over 65 years of age. 1-year retrospective study in an internal medicine department].
Iatrogenic pathology is mainly seen in the elderly. In a one year retrospective study, we showed that drug toxicity was responsible for 87 cases requiring hospitalisation in patients aged 65 years and above (7.7% of hospital admission for patients over 65 years). The major manifestations were: 21 cases of sera electrolyte disturbance, 19 concerning gastro-intestinal tract and liver, 16 cardiological disorders, 13 neurological complications, ten involving the endocrine system, six hematological complications. The most common drugs involved were: antihypertensive agents (36%), of which 20.5% were diuretics, psychotherapeutic drugs (24.8%), anti-inflammatory drugs (17.8%). The average cost per patient was calculated to 20,602 FF per patient. Impossibility for direct return to the original dwelling place was another complication in 29% of hospitalisations related to iatrogenic disorders. The high number of drugs taken daily increases the risk of drug interactions which was responsible for iatrogenic accidents in 12.6% of the patients of this study.
Fradet
G
G
Service de médecine interne et gastroentérologie, centre hospitalier, Luçon, France.
Legac
X
X
Charlois
T
T
Ponge
T
T
Cottin
S
S
D000368:Aged; D000369:Aged, 80 and over; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006748:Hospital Departments; D006760:Hospitalization; D006801:Humans; D007049:Iatrogenic Disease; D007388:Internal Medicine; D008297:Male; D012189:Retrospective Studies
Pathologie iatrogène médicamenteuse après 65 ans, responsable d'une hospitalisation. Etude rétrospective sur 1 an dans un service de médecine interne.