Stressors, including social conflict, decrease plasma prolactin in male golden hamsters.
Following exposure to a stressor, plasma prolactin (PRL) rises in most species. The purpose of the present study was to examine the effect of social conflict or of footshock stress on PRL responsiveness in male Syrian hamsters. Contrary to expectations, PRL was significantly lower in subordinate hamsters than in their dominant opponents or in controls following one, five, or nine exposures to social conflict. Similarly, PRL was reduced in hamsters subjected to a mild footshock stressor. By contrast, adrenocorticotropin, another stress-responsive hormone, was elevated following exposure to each of these stressors. We also demonstrate that PRL release is inhibited by dopamine as it is in other species by showing that there is a dose-dependent increase in PRL release following treatment with the dopamine receptor blocker, domperidone.
Huhman
K L
KL
Department of Biology and Psychology, Georgia State University, Atlanta 30303, USA.
Mougey
E H
EH
Moore
T O
TO
Meyerhoff
J L
JL
D000324:Adrenocorticotropic Hormone / Q000097:blood; D000378:Agonistic Behavior / Q000502:physiology; D000818:Animals; D001143:Arousal / Q000502:physiology*; D006224:Cricetinae; D004291:Dominance-Subordination; D005239:Fear / Q000502:physiology*; D008297:Male; D008647:Mesocricetus / Q000502:physiology*; D011388:Prolactin / Q000097:blood*; D011954:Receptors, Dopamine / Q000502:physiology; D012931:Social Environment; D013045:Species Specificity
D011954:Receptors, Dopamine; D000324:Adrenocorticotropic Hormone; D011388:Prolactin