[Mycobacterium avium-intracellulare subcutaneous abscess after injections of interferon alpha in a patient treated for lymphoma].
BACKGROUND
Cutaneous involvement with Mycobacterium avium-intracellulare is usually observed in disseminated disease but cutaneous infection alone without bacteraemia is uncommon.


METHODS
We report a case of Mycobacterium avium-intracellulare subcutaneous abscess of the thigh in a 32-year-old woman with lymphoma. The lesion was treated with drainage, excision and chemotherapeutic agents. Inoculation was probably secondary to alpha interferon injections performed during one year.


CONCLUSIONS
The review of the literature shows that isolated Mycobacterium avium-intracellulare skin infections are rare, probably induced by traumatic percutaneous inoculation, frequently in immunocompromised patients. The pro-infectious effect of interferon alpha is considered. Treatment is unsatisfactory and surgical excision is often necessary.
Philippot
V
V
Service de Dermatologie, Hôpital de l'Hôtel-Dieu, Lyon.
Yassir
F
F
Balme
B
B
Perrot
H
H
D000038:Abscess / Q000209:etiology* / Q000601:surgery; D000328:Adult; D003646:Debridement; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy*; D015270:Mycobacterium avium-intracellulare Infection / Q000188:drug therapy / Q000209:etiology*; D012008:Recurrence; D012878:Skin Neoplasms / Q000188:drug therapy*; D013848:Thigh
D016898:Interferon-alpha
Abcès sous-cutané à Mycobacterium avium-intracellulare après injections d'interféron alpha chez une malade traitée pour lymphome.