title: Short term respiratory health effects of ambient air pollution: results of the APHEA project in Paris.
abstract: OBJECTIVE
  To quantify the short term respiratory health effects of ambient air pollution in the Paris area.
  
  
  METHODS
  Time series analysis of daily pollution levels using Poisson regression.
  
  
  METHODS
  Paris, 1987-92.
  
  
  RESULTS
  Air pollution was monitored by measurement of black smoke (BS) (15 monitoring stations), sulphur dioxide (SO2), nitrogen dioxide (NO2), particulate matter less than 13 microns in diameter (PM13), and ozone (O3) (4 stations). Daily mortality and general admissions to public hospitals due to respiratory causes were considered. The statistical analysis was based on a time series procedure using linear regression modelling followed by a Poisson regression. Meterological variables, epidemics of influenza A and B, and strikes of medical staff were included in the models. The mean daily concentration of PM13 and daily 1 hour maximum of SO2 significantly affected daily mortality from respiratory causes. An increase in the concentration of PM13 of 100 micrograms/m3 above its 5th centile value increased the risk of respiratory death by 17%. PM13 and BS were also associated with hospital admissions due to all respiratory diseases (4.1% increased risk when the BS level exceeded its 5th centile value by 100 micrograms/m3). SO2 levels consistently influenced hospital admissions for all respiratory diseases, chronic obstructive pulmonary disease, and asthma. Asthma was also correlated with NO2 levels.
  
  
  CONCLUSIONS
  These results indicate that even though the relative risk is weak in areas with low levels of pollution, ambient air pollution, and especially particulate matter and SO2, nonetheless require attention because of the number of people exposed and the existence of high risk groups.
authors: Ecole Nationale de Santé Publique and Service des Etudes Médicales EDF-GDF, Saint-Maurice, France.
authors: W
authors: W
authors: Dab
authors: S
authors: S
authors: Medina
authors: P
authors: P
authors: Quénel
authors: Y
authors: Y
authors: Le Moullec
authors: A
authors: A
authors: Le Tertre
authors: B
authors: B
authors: Thelot
authors: C
authors: C
authors: Monteil
authors: P
authors: P
authors: Lameloise
authors: P
authors: P
authors: Pirard
authors: I
authors: I
authors: Momas
authors: R
authors: R
authors: Ferry
authors: B
authors: B
authors: Festy
mesh_terms: D000293:Adolescent; D000328:Adult; D000393:Air Pollutants / Q000009:adverse effects / Q000032:analysis; D000397:Air Pollution / Q000009:adverse effects* / Q000032:analysis; D004391:Dust / Q000009:adverse effects / Q000032:analysis; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008875:Middle Aged; D009585:Nitrogen Dioxide / Q000009:adverse effects / Q000032:analysis; D016017:Odds Ratio; D010297:Paris / Q000453:epidemiology; D012044:Regression Analysis; D012120:Respiration Disorders / Q000453:epidemiology* / Q000401:mortality; D012621:Seasons; D012906:Smoke / Q000009:adverse effects / Q000032:analysis; D013458:Sulfur Dioxide / Q000009:adverse effects / Q000032:analysis
chemical_list: D000393:Air Pollutants; D004391:Dust; D012906:Smoke; D013458:Sulfur Dioxide; D009585:Nitrogen Dioxide