title: Pressure-cross-sectional area relations and elasticity in the rabbit oesophagus in vivo.
abstract: The aim was to assess the luminal cross-sectional area (CSA) and the passive elastic properties of the oesophageal body under luminal pressure loading in anaesthetized rabbits. Stepwise inflation of a luminal balloon, in which the CSA and pressure were measured by means of impedance planimetry and perfused low-compliance manometry, provided the distension stimulus. The parameters of elasticity were computed from steady state values of these measurements. The steady state pressure-CSA and pressure-radius relations were nonlinear. At the lowest and highest luminal pressure load of 1 and 10 kPa, the steady state CSAs were 39 +/- 3 and 91 +/- 4 mm2, respectively. The circumferential tension-strain distribution was nonlinear and showed an exponential behaviour that fitted well to the function tension = a.e(b.strain). Differentiation of the function yielded the wall stiffness which also showed an exponential behaviour.
authors: Institute of Experimental Clinical Research, University of Aarhus, Denmark.
authors: H
authors: H
authors: Gregersen
authors: L L
authors: LL
authors: Christensen
mesh_terms: D000818:Animals; D002404:Catheterization; D003187:Compliance; D004547:Elastic Tissue; D004947:Esophagus / Q000502:physiology*; D009130:Muscle, Smooth / Q000502:physiology; D011817:Rabbits