title: [Synthesis and activities of fragments of inhibin alpha subunit].
abstract: For further investigation of inhibin which is available only by laborious isolation, four fragments of inhibin alpha subunit (7-28, 37-65, 1-32, Y-1-32) were prepared by solid phase peptide synthesis using the Fmoc strategy. The effects of these fragments on progesterone production of rat corpus luteal (CL) cells in vitro were examined. The results indicate that these four fragments induced significant decrease of basic progesterone production.
authors: Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing.
authors: Y
authors: Y
authors: Sun
authors: G S
authors: GS
authors: Lu
authors: D X
authors: DX
authors: Wang
authors: J H
authors: JH
authors: Zhang
authors: Z P
authors: ZP
authors: Cheng
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005260:Female; D007265:Inhibins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008184:Luteal Cells / Q000378:metabolism; D008969:Molecular Sequence Data; D010446:Peptide Fragments; D011374:Progesterone / Q000096:biosynthesis; D051381:Rats
chemical_list: D010446:Peptide Fragments; D011374:Progesterone; D007265:Inhibins