[Local destruction of Deiters' lateral vestibular nucleus (an experimental model of a focal brain stem lesion)].
The experimental rat model of the local brainstem destruction by isolated electrical coagulation of the lateral vestibular nucleus Deiters was offered for studying the adaptive-compensatory CNS reactions after acute brainstem lesions. Morphological changes and functional derangements were correlated in 22 animals. Neurological disorders and behavioural reactions were reproducible and stable in rats with exact localization of coagulated foci. The results demonstrate the adequacy of the proposed model.
Sharova
E V
EV
Novikova
M R
MR
Mikheeva
T S
TS
Shishkina
L V
LV
Lushchekina
E A
EA
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology; D001933:Brain Stem / Q000473:pathology; D004195:Disease Models, Animal; D004598:Electrosurgery; D008297:Male; D051381:Rats; D003689:Vestibular Nucleus, Lateral / Q000502:physiology* / Q000601:surgery
Lokal'noe razrushenie lateral'nogo vestibuliarnogo iadra Deĭstersa (éksperimental'naia model' ochagovogo porazheniia stvola mozga).