title: Prenatal aspects of giant fetal cranial haemangio-endothelioma.
abstract: A case of a large vascular lesion of the skull is reported. The lesion was discovered at 22 weeks' gestation and it rapidly increased in size, reaching 8 cm a month later. Tumor echogenicity was the same as that for soft tissues and colour Doppler examination revealed intense vascularization. Cordocentesis showed features of the Kasabach-Merritt syndrome and very high plasma levels of alpha-fetoprotein. A Caesarean section was performed to avoid dystocia and led to the birth of a baby with cardiac failure in the immediate neonatal period. Biopsies of the mass led to the diagnosis of a non-malignant haemangio-endothelioma. The mass was removed and plastic surgery performed. The baby is alive and well 9 months after the operation.
authors: Fetal Medicine Unit, Hopital Arnaud de Villeneuve, Montpellier, France.
authors: P
authors: P
authors: Boulot
authors: F
authors: F
authors: Deschamps
authors: F
authors: F
authors: Montoya
authors: P
authors: P
authors: Montoya
authors: A
authors: A
authors: Couture
authors: J L
authors: JL
authors: Ferran
authors: G
authors: G
authors: Lefort
mesh_terms: D000328:Adult; D000792:Angiography; D017218:Cordocentesis; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006390:Hemangioendothelioma / Q000098:blood supply / Q000151:congenital / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008026:Ligation; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000379:methods*; D012888:Skull Neoplasms / Q000098:blood supply / Q000151:congenital / Q000175:diagnosis*; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins