Bacteriologic profile and drug resistance in pediatric patients with symptomatic bacteriuria.
The bacteriologic profile in 1081 pediatric patients with culture-positive symptomatic bacteriuria was studied over a 30-month period in a 500-bed acute care hospital in Riyadh, Saudi Arabia. Microbial isolates were considered significant if their numbers equaled or exceeded 10,000 colony-forming units/mL in symptomatic patients. Escherichia coli was the most common causative agent of urinary tract infections (55.1%), followed by Pseudomonas aeruginosa (11.9%), Klebsiella pneumoniae (10.0%), and Enterococcus species (6.1%). Results of antimicrobial susceptibility testing indicated that nitrofurantoin and cephradine may be used as empiric therapy pending laboratory investigation; gentamicin can be added in the treatment in severely ill inpatients, and treatment can be modified when microbiologic results become available.
al-Mugeiren
M M
MM
King Khalid University Hospital, Riyadh, Saudi Arabia.
Qadri
S M
SM
D000667:Ampicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001437:Bacteriuria / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D007223:Infant; D007711:Klebsiella pneumoniae / Q000187:drug effects; D010406:Penicillins / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012529:Saudi Arabia; D013420:Sulfamethoxazole / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D010406:Penicillins; D000667:Ampicillin; D014295:Trimethoprim; D013420:Sulfamethoxazole