[The clinical value of BMIPP on the evaluation of myocardial ischemia and metabolism before and after CABG].
To evaluate the clinical usefulness of BMIPP (15-(p-[125I]-iodophenyl)-3-R, S-methylpentadecanoic acid), BMIPP and T1 imaging were underwent before and after surgery in 25 CABG patients. Preoperatively the demonstrated lesion on BMIPP scintigram is almost the same as that on rest-T1 scintigram. A month after CABG, the recovery on T1 scintigram was remarkable, however improvement on BMIPP was limited. These results suggest that on the evaluation of myocardial ischemia, the clinical value of BMIPP is almost the same as that of rest-T1 before CABG. The postoperative discrepancy between T1 and BMIPP scintigram suggests that the restoration of myocardial circulation does not directly improve myocardial metabolism.
Hayashi
I
I
Division of Thoracic and Cardivascular Surgery, Juntendo University, Tokyo, Japan.
Makuuchi
H
H
Naruse
Y
Y
Kobayashi
T
T
Yamamoto
T
T
Hariya
A
A
Maruno
H
H
Murata
H
H
D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D005227:Fatty Acids / Q000493:pharmacokinetics*; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007462:Iodobenzenes / Q000493:pharmacokinetics*; D017202:Myocardial Ischemia / Q000378:metabolism* / Q000601:surgery; D009206:Myocardium / Q000378:metabolism*; D011877:Radionuclide Imaging; D013793:Thallium
D005227:Fatty Acids; D007462:Iodobenzenes; C049338:iodofiltic acid; D013793:Thallium