Current pathological classification of pituitary adenomas.
A classification of pituitary adenomas basing on detailed structural and immunohistochemical studies is accepted world-wide and is mandatory for each pathologist. Monohormonal (densely or sparsely granulated GH cell adenomas, Prolactin cell adenomas, ACTH cell adenomas. FSH/LH cell adenomas, alpha-subunit-only adenomas), bihormonal (mixed GH/Prolactin cell adenomas, mammosomatotroph cell adenomas, acidophil stem cell adenomas), plurihormonal (GH/Prolactin/Glycoprotein-positive adenomas, other Glycoprotein-positive types) and hormone-negative adenomas (null cell adenomas, oncocytic adenomas) have to be differentiated.
Saeger
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Department of Pathology, Marienkrankenhaus, Hamburg, Federal Republic of Germany.
D000236:Adenoma / Q000145:classification / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D009384:Paraneoplastic Endocrine Syndromes / Q000145:classification / Q000473:pathology*; D010902:Pituitary Gland / Q000473:pathology; D010911:Pituitary Neoplasms / Q000145:classification / Q000473:pathology*