[Continuing neurologic assessment in myelodysplasia].
OBJECTIVE
Myelodysplasia produces a neurological lesion with unpredictable urodynamic sequelae. The present study describes our experience in 18 patients with myelodysplasia and vesicourethral dysfunction.


METHODS
The study comprised 18 patients (11 males and 7 females) with myelodysplasia and vesicourethral dysfunction. Patient median age was 15.7 years (range 7 months-57 years) and the mean follow-up was 20 months (range 7-47 months). After physical and neurological examination, all patients underwent a complete urodynamic evaluation, including selective electromyography of the periurethral sphincter and videocystography. The urodynamic studies were repeated regularly during follow-up.


RESULTS
14 patients (67.7%) showed a lower motor neuron vesicourethral dysfunction; 2 (11.1%) had upper motor neuron lesion and 2 (11.1%) mixed motor neuron lesion. During the study period, no alterations were observed in the urodynamic pattern of patients with upper or mixed motor neuron lesions, but 9 patients (64.2%) with lower motor neuron lesions showed changes in the urodynamic pattern compared with the first evaluation, with alterations in bladder compliance being the most frequent.


CONCLUSIONS
Alterations in bladder compliance may arise from neurogenic and nonneurogenic factors. Our findings indicate the need for close urodynamic surveillance of patients with myelodysplasia and vesicourethral dysfunction.
Rapariz González
M A
MA
Servicio de Urología, Hospital Universitario Nuestra Señora del Pino, Universidad de Las Palmas de Gran Canaria, España.
Salinas Casado
J
J
Belón-López Tomasetti
J A
JA
Begara Morillas
F
F
Isorna Martínez
S
S
Resel Estévez
L
L
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009436:Neural Tube Defects / Q000150:complications* / Q000503:physiopathology; D014522:Urethral Diseases / Q000209:etiology* / Q000503:physiopathology; D001745:Urinary Bladder Diseases / Q000209:etiology* / Q000503:physiopathology; D014563:Urodynamics
Evaluación neurourológica continuada en la mielodisplasia.