[The pathogenesis of surgical trauma and the characteristics of its course in planned surgical interventions in the maxillofacial area].
Examinations carried out on 76 patients have shown that systematic surgical interventions into the maxillofacial area produce deep changes in the tissue and serum systems of proteolysis and their inhibitors. Activation of proteolytic enzymes already on the stage of surgical trauma leads to the formation in the operative wound of the focus of endotoxicosis which depresses antitryptic activity of injured tissues and thus promotes the development of purulent complications. The study of the above indexes at the early stages of acute period may serve as a diagnostic test while estimating a severity of operative wound and allows to make prognosis of the development of purulent complications.
Kudinov
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VA
D004487:Edema / Q000201:enzymology / Q000209:etiology; D005145:Face / Q000601:surgery*; D006801:Humans; D007571:Jaw Diseases / Q000201:enzymology / Q000209:etiology; D056948:Orthognathic Surgical Procedures; D010347:Patient Care Planning; D010447:Peptide Hydrolases / Q000378:metabolism; D011183:Postoperative Complications / Q000201:enzymology / Q000209:etiology*; D011480:Protease Inhibitors / Q000378:metabolism; D013997:Time Factors
D011480:Protease Inhibitors; D010447:Peptide Hydrolases
Patogenez operatsionnoĭ travmy i osobennosti ee techeniia pri planovykh khirurgicheskikh vmeshatel'stvakh v cheliustno-litsevoĭ oblasti.