Antibody responses to two encephalomyocarditis virus vaccines in rhesus macaques (Macaca mulatta).
Two groups of rhesus macaques (Macaca mulatta) housed in rodent-controlled outdoor corrals were inoculated with two different encephalomyocarditis virus (EMCV) vaccines. One group (n = 45) received a vaccine made from an inactivated field isolate of virus cultured during an outbreak at a zoo in Florida. This vaccine produced fourfold increases in the titers of 28 animals (62%); the increases persisted for at least 18 months (last test) after a single injection of the vaccine. The other group (n = 51) received a vaccine made from an inactivated porcine field strain of the virus. This vaccine did not produce titers in any of the vaccinees.
Emerson
C L
CL
Division of Veterinary Resources, University of Miami School of Medicine, FL, USA.
Wagner
J L
JL
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis / Q000097:blood*; D000917:Antibody Formation; D018188:Cardiovirus Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D002460:Cell Line; D006224:Cricetinae; D004606:Elephants; D004686:Encephalomyocarditis virus / Q000276:immunology; D005260:Female; D007668:Kidney; D008253:Macaca mulatta; D008297:Male; D013552:Swine; D013997:Time Factors; D014765:Viral Vaccines
D000914:Antibodies, Viral; D014765:Viral Vaccines