title: Lymphadenectomy in stage-III serous cystadenocarcinoma of the ovary.
abstract: OBJECTIVE
  To elucidate the effects of lymphadenectomy on the prognosis for ovarian cancer.
  
  
  METHODS
  A retrospective study of 69 patients with stage-III serous cystadenocarcinoma was performed.
  
  
  RESULTS
  Among the 69 patients, 36 were not treated by lymphadenectomy. Both pelvic and para-aortic lymphadenectomies were performed on 13 patients at the initial operation and on 11 at the second operation. The group (n = 13) treated by both pelvic and para-aortic lymphadenectomies at the initial operation had a disease-free survival rate that was significantly higher than the non-lymphadenectomy group (n = 36) or the group (n = 5) treated by pelvic or para-aortic lymphadenectomy alone (P < 0.04). These 54 patients were subjected to multivariate analysis for lymphadenectomy at the initial operation, and a significant correlation was found between disease-free survival rate and both pelvic and para-aortic lymphadenectomies (P < 0.05).
  
  
  CONCLUSIONS
  These results suggest that systematic lymphadenectomy can reduce the rate of recurrence.
authors: Department of Obstetrics and Gynecology, Shizuoka Saiseikai Hospital, Japan.
authors: H
authors: H
authors: Fukasawa
authors: F
authors: F
authors: Kikkawa
authors: K
authors: K
authors: Tamakoshi
authors: M
authors: M
authors: Kawai
authors: Y
authors: Y
authors: Arii
authors: Y
authors: Y
authors: Tomoda
mesh_terms: D000328:Adult; D000368:Aged; D018284:Cystadenocarcinoma, Serous / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome