[Frontal type dementia and amyotrophic lateral sclerosis. 3 cases with (HmPAO Tc99m) single-photon emission tomography study].
Three cases of rapid onset neuropsychological frontal dementia preceded the development of sporadic amyotrophic lateral sclerosis by 12 to 24 months. HmPAO Tc99m scintigraphy demonstrated hypoactivity in the cortex, predominantly in the frontal region. Three hypotheses are discussed: 1) coincidence between two degenerative diseases, Alzheimer's disease or Pick's disease and ALS; 2) an amyotrophic form of Creutzfeld Jakob disease; 3) pre-senile dementia associated with a motoneuron disease, a clinical pathology entity recently described by Mitzuyama.
Vercelletto
M
M
Clinique Neurologique, CHU Nord, Nantes.
Bertout
C
C
Geffriaud
J
J
Labat
J J
JJ
Magne
C
C
Fève
J R
JR
D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003704:Dementia / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005625:Frontal Lobe; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime
Démence de type frontal et sclérose latérale amyotrophique. Trois cas avec étude en tomographie d'émission monophotonique (HmPAO Tc99m).