title: Regional activation of human cerebral cortex upon an adaptation in mirror drawing.
abstract: To elucidate cerebral regions involved in adaptation to mirror drawing, changes in regional cerebral blood flow were measured using positron emission tomography at different levels of adaptation. A significant signal in subtraction images was localized in left Brodmann's area 45 (ventral sub-region of Broca's area) in the initial phase of the mirror drawing. This activity decreased as adaptation proceeded, and a small cluster in area 19 of the medial extrastriate cortex became significantly active. An after-effect of ca. 30 min of mirror-drawing was also detected in the right area 21 of the temporal association cortex. The results first demonstrated visuo-cortical regions where neurons might change their activity to evoke plastic response to the inverted vision.
authors: Subfemtomole Biorecognition Project, Research Development Corporation of Japan, Osaka, Japan. imamura@obi.or.jp
authors: K
authors: K
authors: Imamura
authors: H
authors: H
authors: Onoe
authors: Y
authors: Y
authors: Watanabe
authors: J
authors: J
authors: Andersson
authors: J
authors: J
authors: Hetta
authors: H
authors: H
authors: Schneider
authors: R
authors: R
authors: Reineck
authors: K
authors: K
authors: Lidström
authors: M
authors: M
authors: Okura
authors: B
authors: B
authors: Långström
mesh_terms: D000223:Adaptation, Psychological / Q000502:physiology*; D000328:Adult; D002560:Cerebrovascular Circulation / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D009473:Neuronal Plasticity / Q000502:physiology; D011597:Psychomotor Performance / Q000502:physiology*; D014055:Tomography, Emission-Computed; D014793:Visual Cortex / Q000033:anatomy & histology / Q000098:blood supply / Q000502:physiology*