Effects of sino-aortic denervation on spectral characteristics of blood pressure and pulse interval variability: a wide-band approach.
Sino-aortic denervation (SAD) is employed in cats to evaluate the baroreflex influence on blood pressure (BP) and pulse interval (PI) spectral components from 0.00008 to 0.9 Hz as assessed by FFT wide-band spectra and their 1/f modelling; and the linear coupling between BP and PI and between systolic and diastolic BP as assessed by coherence analysis. Specific procedures have been developed to obtain an effective smoothing of spectra and coherence functions. SAD induced an increase in BP powers from 0.03 to 0.0006 Hz and a power reduction of most of the remaining BP components; a reduction of PI powers at all frequencies; marked deviations of BP spectra from the 1/f trend; a reduction of the coherence between BP and PI from 0.12 to 0.5 Hz and a coherence enhancement at lower frequencies. These findings indicate that the arterial baroreflex modulates both fast and slow spectral components of BP and PI; homogeneously enhances PI fluctuations at all frequencies; produces differentiated effects on BP fluctuations along the frequency axis; and at low frequencies exerts the buffering action on BP through strategies which reduce the BP-PI linear link.
Di Rienzo
M
M
LaRC--Centro di Bioingegneria, Fondazione Pro Juventute, Milano, Italy.
Castiglioni
P
P
Parati
G
G
Mancia
G
G
Pedotti
A
A
D000818:Animals; D001011:Aorta / Q000294:innervation; D017704:Baroreflex / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D002415:Cats; D003714:Denervation; D008955:Models, Cardiovascular; D011674:Pulse / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted