[Monoclonal gammopathy and primary hyperparathyroidism. Apropos of 2 cases and review of the literature].
Frequency of primary hyperparathyroidism (HP) is increased in neoplasia. Though uncommon, both HP and monoclonal gammopathy are not exceptionally associated as seen in a literature review reporting 24 observations. The mechanism of this association remains unclear but does not seems coincidental. Association of hypercalcemia with gammopathy does not suggest systematically malignant hypercalcemia and implies the search for hyperparathyroidism. The authors report two patients presenting respectively a multiple IgD myeloma and an monoclonal gammopathy of undetermined signification associated with a parathyroid adenoma.
Bellou
A
A
Service de médecine D, CHU Nancy-Brabois, Vandoeuvre, France.
Blain
H
H
Guerci
A
A
Jeandel
C
C
D000368:Aged; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000150:complications* / Q000503:physiopathology; D007072:Immunoglobulin D; D008875:Middle Aged; D010265:Paraproteinemias / Q000209:etiology* / Q000503:physiopathology; D010758:Phosphorus / Q000097:blood
D007072:Immunoglobulin D; D010758:Phosphorus
Gammapathie monoclonale et hyperparathyroïdie primitive. A propos de deux observations et revue de la littérature.