title: [Antibiotic sensitivity of anaerobic bacteria isolated during one year (1993)].
abstract: BACKGROUND
  The aim of this study was to determine the antimicrobian susceptibility of the anaerobe bacteria isolated from clinical samples in the authors' department in 1993.
  
  
  METHODS
  The minimum inhibitory concentrations of 10 antimicrobians were determined in microgram/ml for 129 anaerobe bacterias by the microdilution in broth method recommended by the NCCLS.
  
  
  RESULTS
  All The strains were sensitive to chloramphenicol. Metronidazole inhibited all the isolates except A. meyeri and 50% of other non spored gram-positive bacilli. Imipenen and piperacillin-tazobactam were the most active beta lactamics, with only 1 B. fragilis being resistant to both. Clavulanic amoxycillin presented good activity with only 5% from the B. fragilis group, 1 F. mortiferum and 2 P. anaerobius being resistant. In the B. fragilis group 10% were resistant to cefoxitin and 15% to piperacillin. The remaining isolates were sensitive to both antimicrobians. Resistance to clindamycin in the B. fragilis group was 16.7%. There were also strains resistant to Peptostreptococcus, Prevotella and aerotolerant non spored gram-positive bacilli. Penicillin and amoxycillin were the least active antimicrobians.
  
  
  CONCLUSIONS
  Chloramphenicol, metronidazole, imipenem, piperacillin-tazobactam and clavulanic amoxycillin were very effective and showed a wide spectrum of activity versus the strains studied. Cefoxitin, piperacillin and clindamycin maintain good antianaerobe activity.
authors: Servicio de Microbiología, Hospital Juan Canalejo, La Coruña.
authors: M T
authors: MT
authors: Durán
authors: F
authors: F
authors: Molina
mesh_terms: D000900:Anti-Bacterial Agents / Q000145:classification / Q000494:pharmacology; D001421:Bacteria, Anaerobic / Q000187:drug effects* / Q000302:isolation & purification; D001424:Bacterial Infections / Q000453:epidemiology / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Susceptibilidad antimicrobiana de bacterias anaerobias aisladas en un año (1993).