[Relationship between lead content in umbilical blood and neurobehavioral development in infants].
One hundred and thirty-two babies were selected and their umbilical blood lead level were determined as a marker to reflect their exposure, to study the diagnostic criteria for lead poisoning in young children. And, mental development index (MDI) and psychomotor development index (PDI) of three-month babies in Bayley scales of infant development were used as effective indicators to study levels of lead on their development. Results indicated that both MDI and PDI in infants with blood lead levels of greater than or equal to 0.48 mumol/L were obviously lower than those with less than 0.48 mumol/L. All children were divided into two groups (high-blood-lead and low-blood-lead) according to the cut-off values for blood lead of 0.72, 0.48, and 0.24 mumol/L, respectively, and the difference in MDI and PDI between the two groups decreased gradually with the cut-off value shifted down, and there was no difference in them between the two groups when the cut-off point lowering down to 0.24 mumol/L. Therefore, the authors recommended that a level of 0.48 mumol/L of blood lead be used as diagnostic criteria for lead poisoning in young children.
Shen
X
X
Division of Prevention and Treatment of Lead Poisoning in Children, Shanghai Institute for Pediatrics, Shanghai Second Medical University.
Yan
C
C
Zhou
J
J
D002657:Child Development; D004781:Environmental Exposure; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007223:Infant; D018730:Infant Behavior; D007231:Infant, Newborn; D007854:Lead / Q000097:blood*; D007855:Lead Poisoning / Q000175:diagnosis*; D008297:Male; D009483:Neuropsychological Tests; D011446:Prospective Studies; D012015:Reference Standards
D007854:Lead