[Lipid metabolism parameters in patients with multi-infarct dementia and Alzheimer's type dementia].
The concentrations were determined of triglycerides (TG), total cholesterol (Ch), high density fraction of (HDL-Ch), low density fraction of cholesterol (LDL-Ch), apolipoprotein B (apo-B) in patients with dementia of Alzheimer type (DAT, 14 patients) and multi-infarct dementia (MID, 63 patients). No significant differences in the estimated lipid parameters in both groups were found, except the calculated value of atherogenic index (Ch/HDL-Ch), which was significantly higher in patients with MID. Our results suggest that this parameter is a much more sensitive atherogenic indicator in blood-vessels than other tested lipid parameters. This finding may influence the therapeutic approach to patients with dementia.
Sygitowicz
G
G
Katedry i Zakładu Biochemii i Chemii Klinicznej AM w Warszawie.
Minor
A
A
Pachecka
J
J
Jura
E
E
Ryglewicz
D
D
Członkowska
A
A
D000328:Adult; D000368:Aged; D000544:Alzheimer Disease / Q000097:blood* / Q000378:metabolism*; D001055:Apolipoproteins B / Q000097:blood* / Q000378:metabolism*; D008076:Cholesterol, HDL / Q000097:blood* / Q000378:metabolism*; D008078:Cholesterol, LDL / Q000097:blood* / Q000378:metabolism*; D015161:Dementia, Multi-Infarct / Q000097:blood* / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood* / Q000378:metabolism*
D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides
Parametry gospodarki lipidowej u pacjentów z otepieniem naczyniopochodnym i otepieniem typu alzheimerowskiego.