Rev-erb beta 2, a novel isoform of the Rev-erb family of orphan nuclear receptors.
We have isolated a rat complementary DNA clone corresponding to a novel isoform of the hormone nuclear receptor superfamily. This clone encodes a 383 amino acid residue protein designated as Rev-erb beta 2. This protein is identical until residue 382 to the Rev-erb beta 1 protein, which is 195 amino acids longer. Several arguments pointed out that the Rev-erb beta 2 cDNA may originate from the same gene as Rev-erb beta 1 by alternative splicing and using a different polyadenylation site. Our results indicate that Rev-erb beta 2 is a new isoform of the Rev-erb family of orphan nuclear receptors.
Giambiagi
N
N
Unité d'Expression des Gènes Eucaryotes, Institut Pasteur, Paris, France.
Cassia
R
R
Petropoulos
I
I
Part
D
D
Cereghini
S
S
Zakin
M M
MM
Ochoa
A
A
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000302:isolation & purification*; D008969:Molecular Sequence Data; D051381:Rats; D011956:Receptors, Cell Surface / Q000032:analysis*; D018160:Receptors, Cytoplasmic and Nuclear / Q000302:isolation & purification*; D011988:Receptors, Thyroid Hormone
D004268:DNA-Binding Proteins; D011956:Receptors, Cell Surface; D018160:Receptors, Cytoplasmic and Nuclear; D011988:Receptors, Thyroid Hormone