Kinesin and myosin: molecular motors with similar engines.
Structure determination of the catalytic domains of two members of the kinesin superfamily reveals that this class of molecular motor exhibits the same architecture as myosin and suggests that these microtubule- and actin-based motors arose from a common ancestor.
Rayment
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Institute for Enzyme Research, University of Wisconsin, Madison 53705, USA.
D000199:Actins / Q000737:chemistry; D000818:Animals; D029721:Drosophila Proteins; D016547:Kinesins / Q000737:chemistry* / Q000502:physiology; D008868:Microtubule Proteins / Q000737:chemistry; D008870:Microtubules / Q000502:physiology; D008958:Models, Molecular; D009218:Myosins / Q000737:chemistry* / Q000502:physiology; D017434:Protein Structure, Tertiary; D014404:Tubulin / Q000737:chemistry
D000199:Actins; D029721:Drosophila Proteins; D008868:Microtubule Proteins; D014404:Tubulin; C066696:ncd protein, Drosophila; D009218:Myosins; D016547:Kinesins