A field trial of the ParaSight-F test for the diagnosis of Plasmodium falciparum infection.
The rapid manual ParaSight-F test for Plasmodium falciparum is an antigen capture test detecting trophozoite-derived histidine rich protein II, is simple and provides a definitive diagnosis within 10 min. Compared with 913 thick blood film examinations, the ParaSight-F test had 93.4% sensitivity and 98.2% specificity. Compared with 520 blood samples within the same study examined with the aid of the polymerase chain reaction, the ParaSight-F test had 91.6% sensitivity and 99.4% specificity. The ParaSight-F test could be a valuable diagnostic tool for falciparum malaria in any situation requiring rapid diagnosis in the absence of microscopical examination.
Banchongaksorn
T
T
Malaria Centre Region 2, Amphur Muang, Chiang Mai, Thailand.
Yomokgul
P
P
Panyim
S
S
Rooney
W
W
Vickers
P
P
D000818:Animals; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis*; D010274:Parasitology / Q000379:methods; D010963:Plasmodium falciparum / Q000302:isolation & purification*; D010965:Plasmodium malariae / Q000302:isolation & purification; D010966:Plasmodium vivax / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D012680:Sensitivity and Specificity; D013785:Thailand
D011933:Reagent Kits, Diagnostic