Allgrove syndrome: documenting cholinergic dysfunction by autonomic tests.
We describe two Hispanic adolescents with Allgrove syndrome (alacrima, achalasia, and sensorimotor polyneuropathy) in whom we documented cholinergic dysfunction by cardiovascular autonomic tests. Both patients had orthostatic hypotension and decreased heart rate variability.
Chu
M L
ML
Center for Neuromuscular and Developmental Disorders, Hospital for Joint Diseases, New York, New York, USA.
Berlin
D
D
Axelrod
F B
FB
D000293:Adolescent; D015352:Dry Eye Syndromes; D004931:Esophageal Achalasia; D005260:Female; D006801:Humans; D008297:Male; D009468:Neuromuscular Diseases; D010641:Phenotype; D012678:Sensation Disorders; D013577:Syndrome