title: Angioscopically-assisted in situ saphenous vein bypass for infrainguinal revascularisation.
abstract: OBJECTIVE
  The diagnostic capability of angioscopy for endoluminal evaluation is established and its superiority over arteriography for completion studies has been confirmed. The therapeutic use of angioscopy in vein graft preparation is more controversial. The aim of this prospective study was to establish whether angioscopic vein preparation confers real benefits over existing techniques.
  
  
  METHODS
  Forty-seven patients were randomised to either full angioscopic (ANG) vein preparation (23 patients) or conventional (CON) in situ grafting (19 patients). All patients underwent completion studies with arteriography and angioscopy and postoperatively, entered a Duplex graft surveillance programme.
  
  
  RESULTS
  There was a significant difference in the incidence of wound morbidity: 26% in the ANG group as against 63% in the CON group (Fisher's exact test: p = 0.043), but no significant differences with respect to duration of operation, duration of vein graft preparation, length of hospital stay and both 30 day and 12 month secondary cumulative patencies (log rank test: p > 0.5). Completion angioscopy detected eight persistent valve cusps in six patients, all missed at arteriography, but failed to detect arteriovenous fistulae.
  
  
  CONCLUSIONS
  Angioscopic preparation reduces wound morbidity and complements arteriography for detecting intraoperative defects. A large, prospective, randomised trial is now warranted to fully evaluate the potential therapeutic role of angioscopy with respect to current vascular practice.
authors: Vascular Studies Unit, Bristol Royal Infirmary, U.K.
authors: Y G
authors: YG
authors: Wilson
authors: A H
authors: AH
authors: Davies
authors: I C
authors: IC
authors: Currie
authors: C
authors: C
authors: McGrath
authors: M
authors: M
authors: Morgan
authors: R N
authors: RN
authors: Baird
authors: P M
authors: PM
authors: Lamont
mesh_terms: D000368:Aged; D017546:Angioscopy; D001166:Arteriovenous Shunt, Surgical / Q000379:methods; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery*; D007430:Intraoperative Care / Q000379:methods; D007511:Ischemia / Q000601:surgery*; D007866:Leg / Q000098:blood supply; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000517:prevention & control; D011446:Prospective Studies; D012501:Saphenous Vein / Q000033:anatomy & histology / Q000637:transplantation*; D018616:Ultrasonography, Doppler, Duplex