Analysis of thermal injury process based on enzyme deactivation mechanisms.
Based upon the analysis of enzyme-catalyzed reactions occurring in living tissue, a model of thermal injury process is presented in which the fraction of denatured enzyme protein was taken as the indicator of thermal damage degrees. The results from this model describe the dependence of thermal damage on exposure time and temperature elevation.
Xu
Y
Y
Department of Engineering Mechanics, Tsinghua University, Beijing, China.
Qian
R
R
D002056:Burns / Q000503:physiopathology*; D002470:Cell Survival / Q000502:physiology; D004798:Enzymes / Q000502:physiology*; D006801:Humans; D008962:Models, Theoretical; D011489:Protein Denaturation / Q000502:physiology*; D013696:Temperature; D013997:Time Factors
D004798:Enzymes