title: [CAA 19-9 and carcinoembryonic antigen in gallbladder cancer].
abstract: The aim of this work was to assess the diagnostic yield of serum tumoral markers, Ca 19-9 and carcinoembryonic antigen, in patients with gallbladder cancer. We studied 54 patients of whom 33 had gallbladder cancer and in 21 the tumor was removed previously and were presently free of disease. Twenty one patients with cholelithiasis were used as controls. Ca 19-9 was over 37 U/ml in 22 (65%) patients with cancer, in two patients free of disease and in two controls. The sensitivity and specificity of Ca 19-9 was 0.66 and 0.90 respectively. Carcinoembryonic antigen was over 2.5 ng/ml in 25 patients with cancer (56%) and its sensitivity and specificity was 0.75 and 0.71 respectively. Using a cutoff point of 4 ng/ml, these figures were 0.51 and 0.9 respectively. The better predictive capacity was given by a Ca 19-9 over 37 U/ml or a carcinoembryonic antigen over 4 ng/ml. It is concluded that, although the sensitivity and specificity of these markers was adequate in this work, one must bear in mind that studied patients had advanced tumors.
authors: Departamento de Cirugía, Universidad de la Frontera, Temuco, Chile.
authors: X
authors: X
authors: de Aretxabala
authors: J P
authors: JP
authors: Riedeman
authors: I
authors: I
authors: Roa
authors: C
authors: C
authors: Wenzel
authors: J
authors: J
authors: Inostroza
authors: L
authors: L
authors: Burgos
authors: J
authors: J
authors: Carlos Araya
authors: S
authors: S
authors: Siegel
authors: L
authors: L
authors: Millaqueo
authors: R
authors: R
authors: Espinoza
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D005260:Female; D005500:Follow-Up Studies; D005706:Gallbladder Neoplasms / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen
vernacular_title: CA 19-9 y antígeno carcino-embrionario en cáncer de la vesícula biliar.