[Studies on transcranial magnetic stimulation--Part 2. Pathological findings of rabbit brain after long-term stimulation based on characteristics of intracerebral induced voltage].
I investigated the safety of transcranial magnetic stimulation (TMS) with a double coil. Induced voltages of a double coil compared in rabbit brain with those in the atmosphere were almost equal. When the distance from the coil's surface was disregarded, the maximum induced voltage spot did not move. Based on these characteristics of a double coil, the safety of TMS was examined in rabbit brain and brainstem tissues using high magnetic pulses (2.4 tesla) and high frequencies (100 approximately 200 stimuli per day, total of 5,000 stimuli), over a long-term period (30 approximately 42 days). Under these conditions, the brain and brainstem tissues showed no abnormal lesions. In conclusion, I suggest that TMS with a double coil does not influence the brain tissues such as the visual conduction system and the ocular motor system, under the above conditions.
Nishikiori
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Department of Ophthalmology, Kawasaki Medical School, Okayama, Japan.
D000818:Animals; D001921:Brain / Q000473:pathology* / Q000502:physiology; D005071:Evoked Potentials; D011817:Rabbits; D050781:Transcranial Magnetic Stimulation