title: Isolation and characterization of the first simian immunodeficiency virus from a feral sooty mangabey (Cercocebus atys) in West Africa.
abstract: The lineage of HIV-2-like viruses was studied in feral sooty mangabeys (SMs) by serological and genetic methods. Four feral sooty mangabeys were positive for simian immunodeficiency virus (SIV) antibodies and a new isolate, SIVsmSL92a, was obtained. Genetic analysis of gag genes showed that SIVsmSL92a was highly diverse and a distinct sequence subtype within the SIV sm/HIV-2 family. The results showed that SIVsm is the most diverse group of SIVs found thus far in a single monkey species.
authors: Department of Microbiology, New York University Medical Center, NY, 10016, US
authors: Z
authors: Z
authors: Chen
authors: P
authors: P
authors: Telfer
authors: P
authors: P
authors: Reed
authors: L
authors: L
authors: Zhang
authors: A
authors: A
authors: Getti
authors: D D
authors: DD
authors: Ho
authors: P A
authors: PA
authors: Marx
mesh_terms: D000354:Africa, Western; D000818:Animals; D001483:Base Sequence; D015153:Blotting, Western; D016665:Cercocebus atys / Q000821:virology*; D003001:Cloning, Molecular; D003429:Cross Reactions; D015683:Gene Products, gag / Q000737:chemistry / Q000235:genetics*; D007963:Leukocytes, Mononuclear / Q000821:virology; D008253:Macaca mulatta / Q000821:virology; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D012698:Serologic Tests; D015302:Simian Immunodeficiency Virus / Q000235:genetics* / Q000302:isolation & purification*
chemical_list: D015683:Gene Products, gag