Innate defect? Bronchial epithelial cells of atopic patients with asthma lack the ability to activate allergens.
Kimber
I
I
Zeneca Central Toxicology Lab, Macclesfield, UK.
D000485:Allergens / Q000009:adverse effects / Q000378:metabolism*; D001249:Asthma / Q000209:etiology / Q000503:physiopathology*; D001980:Bronchi / Q000166:cytology / Q000503:physiopathology*; D002463:Cell Membrane Permeability; D003713:Dendritic Cells / Q000166:cytology / Q000378:metabolism; D004847:Epithelial Cells; D004848:Epithelium / Q000503:physiopathology; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000096:biosynthesis; D006801:Humans
D000485:Allergens; D016178:Granulocyte-Macrophage Colony-Stimulating Factor