Treatment of diabetic gustatory sweating with topical glycopyrrolate cream.
A 42-year-old insulin-dependent diabetic man presented with severe bilateral gustatory sweating associated with a deterioration in his glycaemic control. Conventional oral antimuscarinic medication was contraindicated because of his cardiac insufficiency. Topical 0.5% glycopyrrolate cream was tried and applied on alternate days to his face, which resulted in the complete cessation of his gustatory sweating without side-effects. Topical glycopyrrolate cream is an effective treatment of diabetic gustatory sweating without the adverse effects commonly found with oral anti-muscarinic medication.
Atkin
S L
SL
Scarborough General Hospital, UK.
Brown
P M
PM
D000287:Administration, Topical; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D006442:Glycated Hemoglobin / Q000032:analysis; D006024:Glycopyrrolate / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007003:Hypoglycemia; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D061389:Insulin, Regular, Pork; D008297:Male; D018727:Muscarinic Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D013547:Sweating, Gustatory / Q000188:drug therapy* / Q000209:etiology
D006442:Glycated Hemoglobin; D006024:Glycopyrrolate; D007004:Hypoglycemic Agents; D007328:Insulin; D061389:Insulin, Regular, Pork; D018727:Muscarinic Antagonists; C000006:insulin, neutral