Delayed hypersensitivity reaction to paracetamol (acetaminophen).
We are reporting three patients who experienced delayed cutaneous reactions after treatment with paracetamol (acetaminophen). These reactions were confirmed in controlled challenge tests. Patch tests with paracetamol were positive in all patients. A biopsy performed of the case 1 patch test confirmed that the lesion was compatible with delayed hypersensitivity reaction-type allergic contact dermatitis.
Ibáñez
M D
MD
Servicio de Alergia, Hospital Niño Jesus, Universidad Autonoma de Madrid, Spain.
Alonso
E
E
Muñoz
M C
MC
Martinez
E
E
Laso
M T
MT
D000082:Acetaminophen / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D017449:Dermatitis, Allergic Contact / Q000276:immunology*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004487:Edema; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D010328:Patch Tests
D000082:Acetaminophen