Prevalence of fluorescent monoclonal antibody-nonreactive Neisseria gonorrhoeae in five North American sexually transmitted disease clinics.
We compared a direct fluorescent monoclonal antibody (DFA) test with alternative enzymatic and fermentation tests for identifying presumptive gonococcal isolates in a systematic sample from patients attending five sexually transmitted disease clinics in five cities. Fourteen (2.5%) of 556 isolates from three clinics were nonreactive with DFA confirmatory reagent and reactive by both the Quad-Ferm (BioMerieux Vitek Inc.) and the Rapid NH (Innovative Diagnostic Systems, Inc.) tests. The prevalence of DFA-nonreactive Neisseria gonorrhoeae isolates varies geographically and is independent of local methods for the identification of possible gonococci.
Smith
K R
KR
Department of Medicine, University of Alabama at Birmingham, USA.
Fisher
H C
HC
Hook
E W
EW
D000554:Ambulatory Care Facilities; D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D001431:Bacteriological Techniques; D005069:Evaluation Studies as Topic; D005285:Fermentation; D019085:Fluorescent Antibody Technique, Direct; D006069:Gonorrhea / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D007202:Indicators and Reagents; D008297:Male; D009344:Neisseria gonorrhoeae / Q000276:immunology* / Q000302:isolation & purification* / Q000378:metabolism; D014481:United States / Q000453:epidemiology
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D007202:Indicators and Reagents