title: Familial idiopathic atrial fibrillation with bradyarrhythmia.
abstract: A 10-year-old boy is reported who presented with idiopathic atrial fibrillation and bradyarrhythmia. After history of intrauterine and postnatal bradycardia, atrial fibrillation was first documented electrocardiographically at 16 months of age. An underlying structural heart disease was not evident. At the age of 10 years, implantation of a permanent ventricular demand pacemaker was indicated after syncope due to severe bradyarrhythmia. The family history revealed five persons of four generations with bradyarrhythmias. Idiopathic atrial fibrillation known since childhood was documented in three close relatives. A high grade AV block resulting in bradyarrhythmias and the occurrence of ST-T-changes in precordial leads could be demonstrated in all affected family members suggesting a diffuse general conduction abnormality in these patients. In this family, idiopathic atrial fibrillation seems to be transmitted as an autosomal dominant trait.
  
  
  CONCLUSIONS
  Atrial fibrillation without underlying heart disease is extremely rare in children. Careful electrocardiographic follow-up of these patients and the evaluation of ECG recordings of all family members is recommended.
authors: Pediatric Cardiology, Hannover Medical School, Germany.
authors: H
authors: H
authors: Bertram
authors: T
authors: T
authors: Paul
authors: F
authors: F
authors: Beyer
authors: H C
authors: HC
authors: Kallfelz
mesh_terms: D001281:Atrial Fibrillation / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D001919:Bradycardia / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D002648:Child; D004562:Electrocardiography; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial; D010375:Pedigree; D013575:Syncope / Q000209:etiology