[Primary cerebral non-Hodgkin's lymphoma. Intensive chemotherapy supported by crania radiotherapy].
Four cases of primary central nervous system lymphomas treated with high dose cytosine arabinoside and high dose methotrexate prior to cranial irradiation are described. All patients achieved a complete clinical and radiological remission following treatment with chemotherapy alone. Three patients are alive with a follow-up period of 60, 45 og 24 months, respectively. One patient died 12 months after diagnosis at another hospital. Autopsy was not performed.
Jensen
M K
MK
Aalborg Sygehus Syd, medicinsk-haematologisk afdeling B og radiologisk afdeling.
Skejø
H P
HP
Jensen
M K
MK
D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy; D003131:Combined Modality Therapy; D003561:Cytarabine / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage*; D008875:Middle Aged; D011379:Prognosis; D014057:Tomography, X-Ray Computed
D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D003561:Cytarabine; D008727:Methotrexate
Primaert cerebralt non-Hodgkins lymfom. Intensiv kombinationskemoterapi suppleret med kranial stråleterapi.