title: Perioperative morbidity and mortality in combined vs. staged approaches to carotid and coronary revascularization.
abstract: Between 1986 and 1994 we identified 57 patients who underwent carotid endarterectomy (CEA) and coronary artery bypass grafting (CABG) during the same hospitalization. Simultaneous CABG and CEA was performed in 28 patients (mean age 70.5 years, 58% male). Indications for CABG in these patients were myocardial infarction in two crescendo angina in 19, congestive heart failure in two and left main or triple-vessel coronary artery disease noted during carotid preoperative evaluation in five. Indications for CEA were transient ischemic attack (TIA) in 12, crescendo TIA in six, cerebrovascular accident (CVA) in five, and asymptomatic stenosis in five. There were no postoperative myocardial infarctions or perioperative deaths. Two patients developed atrial fibrillation, and four patients had CVAs (two were ipsilateral to the side of CEA). Twenty-nine patients underwent staged procedures (i.e., not performed concomitantly but during the same hospitalization). Indications for CABG and CEA were comparable to those in the group undergoing simultaneous procedures. In 17 patients CEA was performed before CABG. There was a single CVA, the result of an intracerebral hemorrhage. Five of the 17 patients had a myocardial infarction and two died; one patient had first-degree heart block requiring a pacemaker. Four additional patients developed atrial fibrillation, one of whom required cardioversion. The remaining 12 patients had CABG followed by CEA. There were no CVAs, myocardial infarctions, arrhythmias, or deaths in this subgroup. These data demonstrate that the performance of simultaneous CABG and CEA procedures is associated with increased neurologic morbidity (14.3%), both ipsilateral and contralateral to the side of carotid surgery in contrast to staged CABG and CEA (3.4%). In addition, when staged carotid surgery preceded coronary revascularization in those with severe coronary artery disease, the combined cardiac complication and mortality rate was significantly higher than when coronary revascularization preceded CEA. This evidence suggests that when CABG and CEA must be performed during the same hospitalization, the procedures should be staged with CABG preceding CEA.
authors: Department of Surgery, New York University Medical Center, NY, USA.
authors: G
authors: G
authors: Giangola
authors: J
authors: J
authors: Migaly
authors: T S
authors: TS
authors: Riles
authors: P J
authors: PJ
authors: Lamparello
authors: M A
authors: MA
authors: Adelman
authors: E
authors: E
authors: Grossi
authors: S B
authors: SB
authors: Colvin
authors: P F
authors: PF
authors: Pasternak
authors: A
authors: A
authors: Galloway
authors: A T
authors: AT
authors: Culliford
authors: R
authors: R
authors: Esposito
authors: G
authors: G
authors: Ribacove
authors: B K
authors: BK
authors: Crawford
authors: L
authors: L
authors: Glassman
authors: F G
authors: FG
authors: Baumann
authors: F C
authors: FC
authors: Spencer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000601:surgery; D001281:Atrial Fibrillation / Q000209:etiology; D016893:Carotid Stenosis / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000601:surgery; D001026:Coronary Artery Bypass / Q000009:adverse effects; D003327:Coronary Disease / Q000601:surgery; D004554:Electric Countershock; D016894:Endarterectomy, Carotid / Q000009:adverse effects; D005260:Female; D006327:Heart Block / Q000209:etiology; D006333:Heart Failure / Q000601:surgery; D006760:Hospitalization; D006801:Humans; D007431:Intraoperative Complications; D002546:Ischemic Attack, Transient / Q000601:surgery; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology / Q000601:surgery; D010138:Pacemaker, Artificial; D011183:Postoperative Complications; D012189:Retrospective Studies; D015996:Survival Rate