Genetic regulation of border zone formation in female mastomys (Praomys coucha) adrenal cortex.
The unique border zone between the zona fasciculata and z. reticularis of the female adrenal cortex is formed in the wild-colored inbred mastomys (Praomys coucha) strain, MWC, but never in the chamois-colored inbred strain, MCC. This clear strain-specific trait was genetically analyzed using F1, F2, and backcross progenies produced between MWC and MCC. Reciprocal crosses gave no significant differences in the phenotypic ratio of F1 or F2 progeny. Border zone formation was detected in 0% of F1 females, 25.8% of F2 females, 0% of backcross females between F1 and MCC, and 47.7% of backcross females between F1 and MWC. From these results, it was concluded that border zone formation in the female MWC adrenal is regulated by a single autosomal recessive gene and this gene was named bzf (border zone formation).
Tanaka
S
S
Institute of Medical Science, University of Tokyo, Japan.
Nozaki-Ukai
M
M
Kitoh
J
J
Matsuzawa
A
A
D000302:Adrenal Cortex / Q000033:anatomy & histology*; D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D008297:Male; D009115:Muridae / Q000235:genetics*; D015383:Zona Fasciculata / Q000033:anatomy & histology; D015385:Zona Reticularis / Q000033:anatomy & histology