An indolent type of Epstein-Barr virus-associated T-cell-rich B-cell lymphoma of the skin: report of a case.
A 74-year-old Japanese man presented with systemic lymphadenopathy, hepatosplenomegaly, and erythroderma in December 1991. A characteristic pattern of anti-EBV antibodies was suggestive of latent EBV infection. A skin tumor biopsied in April 1993 contained biclonal EBV genomes diffusely in the infiltrate of polyclonal T cells and monoclonal B cells. The clinical course was rather mild in contrast to that of classical EBV-associated disorders. Our case was considered a rare indolent type of EBV-associated T-cell-rich B-cell lymphoma of the skin.
Take
H
H
Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Japan.
Kubota
K
K
Fukuda
T
T
Shinonome
S
S
Ishikawa
O
O
Shirakura
T
T
D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D016679:Genome, Viral; D006566:Herpesviridae Infections / Q000150:complications; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000276:immunology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology* / Q000821:virology*; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology* / Q000821:virology*; D013601:T-Lymphocytes / Q000473:pathology*; D014412:Tumor Virus Infections / Q000150:complications
D000914:Antibodies, Viral