Myasthenia gravis and primary biliary cirrhosis. Common immunological features and rare coincidence.
A 43-year-old woman with recently diagnosed primary biliary cirrhosis developed antibody-negative myasthenia gravis. She did not receive D-penicillamine therapy. Clinical and immunological features of this patient are discussed. In previous reports on an association between primary biliary cirrhosis and myasthenia D-penicillamine treatment was an obligate causal linkage between both disorders.
Kiechl
S
S
Department of Neurology, University Clinic Innsbruck, Austria.
Kohlendorfer
U
U
Willeit
J
J
Pohl
P
P
Vogel
W
W
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis / Q000276:immunology*; D008111:Liver Function Tests; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000276:immunology*; D011950:Receptors, Cholinergic / Q000276:immunology
D001323:Autoantibodies; D007074:Immunoglobulin G; D011950:Receptors, Cholinergic