title: WW domains.
abstract: WW domains are recently described protein-protein interaction modules; they bind to proline-rich sequences that usually also contain a tyrosine. These domains have been detected in several unrelated proteins, often alongside other domains. Recent studies suggest that WW domains in specific proteins may play a role in diseases such as hypertension or muscular dystrophy.
authors: Hospital For Sick Children, Division of Respiratory Research, Toronto, Ontario, Canada.
authors: O
authors: O
authors: Staub
authors: D
authors: D
authors: Rotin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D016384:Consensus Sequence; D016189:Dystrophin / Q000235:genetics / Q000502:physiology; D006801:Humans; D008956:Models, Chemical; D008969:Molecular Sequence Data; D011392:Proline / Q000737:chemistry; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D014443:Tyrosine / Q000737:chemistry
chemical_list: D016189:Dystrophin; D011506:Proteins; D014443:Tyrosine; D011392:Proline