title: Use of plasma exchange in hereditary deficiency of factor V and factor VIII.
abstract: Combined hereditary deficiency of coagulation factors V and VIII is a very rare bleeding disorder. The severity of bleeding is determined by the level of these factors, although in general, this is less striking than the severe deficiency of either factor alone. We describe in this article a patient with this congenital defect, and the preoperative management for major surgery.
authors: Center of Thrombosis and Hemostasis, University of North Carolina at Chapel Hill 27599-7305, USA.
authors: A S
authors: AS
authors: Sallah
authors: P
authors: P
authors: Angchaisuksiri
authors: H R
authors: HR
authors: Roberts
mesh_terms: D001803:Blood Transfusion; D003327:Coronary Disease / Q000601:surgery; D005166:Factor V Deficiency / Q000628:therapy*; D005169:Factor VIII / Q000627:therapeutic use; D006467:Hemophilia A / Q000628:therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D011300:Preoperative Care; D011994:Recombinant Proteins
chemical_list: D011994:Recombinant Proteins; D005169:Factor VIII