title: Management of the prescription-drug-dependent adult: case of meprobamate abuse and its treatment.
abstract: Misuse of prescription drugs in the elderly can be a serious problem that is difficult to manage. Prescriptions for non-narcotic central nervous system (CNS) depressants (e.g., anxiolytics and sedative-hypnotics) are commonly written, and their use is associated with severe intoxication and withdrawal effects. The presence of comorbid psychiatric conditions (e.g., depression or panic disorder), for which these agents are prescribed frequently, complicates the clinical picture. This paper, using case examples of meprobamate abuse, describes how physicians can recognize, manage, and treat a patient who is abusing a non-narcotic CNS depressant.
authors: Department of Psychiatry, Georgetown University Medical Center, Boston, Massachusetts, USA.
authors: J J
authors: JJ
authors: Gonzales
authors: A D
authors: AD
authors: Emmerich
authors: S L
authors: SL
authors: Rauch
authors: T A
authors: TA
authors: Stern
mesh_terms: D000328:Adult; D000368:Aged; D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects / Q000627:therapeutic use; D008620:Meprobamate / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D010343:Patient Admission; D019966:Substance-Related Disorders / Q000534:rehabilitation*
chemical_list: D014151:Anti-Anxiety Agents; D006993:Hypnotics and Sedatives; D008620:Meprobamate