Fos expression in rat visual cortex induced by ocular input of ultraviolet light.
We used immunostaining for the cellular transcription factor Fos to assess patterns of neuronal activation in rat visual cortex during exposure to ultraviolet light. Exposure to monochromatic ultraviolet light (lambda max 360 nm: half-bandwidth 8.8 nm, 10 microW/cm2 at eye level) induced strong expression of Fos immunoreactivity in the primary visual cortex and associated cortical visual areas of dark-adapted rats. The stimulatory effect of ultraviolet light on Fos expression was related to exposure duration, was independent of stimulus novelty or phase of the circadian cycle in which exposure occurred, and it was mediated by a mechanism located in the eye. These results demonstrate that ocular input of ultraviolet light is capable of altering neuronal activity in cortical structures involved in visual processing and are consistent with the hypothesis that rodents may use ultraviolet light for vision.
Amir
S
S
Department of Psychology, Concordia University, Montreal, Que, Canada.
Robinson
B
B
D000818:Animals; D003623:Dark Adaptation / Q000502:physiology; D006651:Histocytochemistry; D008297:Male; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis*; D051381:Rats; D017208:Rats, Wistar; D014466:Ultraviolet Rays; D014793:Visual Cortex / Q000033:anatomy & histology / Q000378:metabolism* / Q000528:radiation effects*
D016760:Proto-Oncogene Proteins c-fos