Phenytoin-induced toxic epidermal necrolysis: a case report.
We present a case of phenytoin-induced toxic epidermal necrolysis resulting in 60-70% skin involvement. Systemic corticosteroids and prophylactic antibiotics used initially were discontinued, and subsequent management concentrated on intensive supportive treatment. The patient survived, but is left with disabling ocular complications.
Creamer
J D
JD
St. John's Dermatology Centre, London, UK.
Whittaker
S J
SJ
Kerr-Muir
M
M
Smith
N P
NP
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D005128:Eye Diseases / Q000139:chemically induced / Q000628:therapy; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000473:pathology / Q000628:therapy
D000927:Anticonvulsants; D010672:Phenytoin