Keloidal basal cell carcinoma. A new clinicopathological variant of basal cell carcinoma.
Basal cell carcinoma is the commonest malignant neoplasm of the skin. Clinical and histopathological variants are well known. We describe two patients with nodular lesions on the face, clinically suggestive of keloids, but with no previous history of injury at that site. Histopathological study, in both cases, demonstrated characteristic basaloid neoplastic aggregations of basal cell carcinoma, intermingled with thick, sclerotic, keloidal collagen bundles in the stroma. This peculiar stroma is responsible for the clinical and histopathological characteristics. We propose the name of keloidal basal cell carcinoma for this striking and distinctive variant of basal cell carcinoma.
Requena
L
L
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
Martín
L
L
Fariña
M C
MC
Piqué
E
E
Escalonilla
P
P
D000368:Aged; D002280:Basal Cell Carcinoma / Q000145:classification / Q000473:pathology*; D005153:Facial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007627:Keloid / Q000473:pathology*; D012878:Skin Neoplasms / Q000145:classification / Q000473:pathology*