Impact on USAF tuberculosis detection and control program given a low facility tuberculosis prevalence rate.
Isoniazid prophylaxis is a major part of the U.S. Air Force tuberculosis (TB) screening program and is closely tied to the efforts to eliminate TB. If a facility has a low prevalence rate of TB and there is no sound epidemiological evidence to rule out a false-positive TB skin test, a higher threshold for what constitutes a positive reaction in a given population may be appropriate. Criteria for preventive treatment in Air Force Instruction 48-115, para 3.4.2 and 3.4.5, should be expanded to incorporate the positive-predictive rate of the tuberculin skin test as recommended by the Centers for Disease Control and Prevention.
Popper
S E
SE
74 AMDS/SGPF, Wright-Patterson Air Force Base, OH 45433, USA.
Hebrink
S T
ST
Smith
D A
DA
Stewart
T B
TB
D000995:Antitubercular Agents / Q000627:therapeutic use*; D001499:Bayes Theorem; D003140:Communicable Disease Control / Q000191:economics; D003365:Costs and Cost Analysis; D005189:False Positive Reactions; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008403:Mass Screening; D008889:Military Personnel; D009326:Naval Medicine; D015995:Prevalence; D012307:Risk Factors; D014374:Tuberculin Test; D014376:Tuberculosis / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D014481:United States
D000995:Antitubercular Agents; D007538:Isoniazid