title: Equithesin without chloral hydrate as an anaesthetic for rats.
abstract: In 1977 it was reported that chloral hydrate could cause adynamic ileus in rats, leading to morbidity and death. The symptoms were a swollen abdomen, lethargy and anorexia. However, chloral hydrate is still used as an anaesthetic, particularly in Equithesin mixture. We report that Equithesin without chloral hydrate is an effective anaesthetic, with a slightly reduced potency compared to Equithesin itself, and anaesthesia may be maintained for several hours by supplemental doses.
authors: R M
authors: RM
authors: Deacon
authors: J N
authors: JN
authors: Rawlins
mesh_terms: D000758:Anesthesia / Q000662:veterinary*; D000777:Anesthetics / Q000627:therapeutic use*; D000818:Animals; D002697:Chloral Hydrate / Q000627:therapeutic use*; D004338:Drug Combinations; D008278:Magnesium Sulfate / Q000627:therapeutic use*; D008297:Male; D010424:Pentobarbital / Q000627:therapeutic use*; D051381:Rats
chemical_list: D000777:Anesthetics; D004338:Drug Combinations; C034864:chloropent; D002697:Chloral Hydrate; D008278:Magnesium Sulfate; D010424:Pentobarbital