title: The Xenopus laevis homologue of the 64-kDa subunit of cleavage stimulation factor.
abstract: Cleavage stimulation factor (CstF) is composed of three subunits of 50, 64 and 77 kDa, respectively. We report here the identification of a cDNA clone from Xenopus laevis encoding a homologue of the 64-kDa subunit of human CstF. Comparative sequence analysis reveals that these two proteins are highly conserved with the exception of a unique repeat structure found in the human, but not in the X. laevis, protein. Analysis of expression of this mRNA during X. laevis tadpole development indicates a requirement for this protein throughout all stages of development.
authors: Department of Genetics, Trinity College, Dublin 2, Ireland.
authors: S
authors: S
authors: Barbaux
authors: L T
authors: LT
authors: Seery
authors: D R
authors: DR
authors: Schoenberg
authors: G C
authors: GC
authors: Sellar
authors: A S
authors: AS
authors: Whitehead
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D015152:Blotting, Northern; D003001:Cloning, Molecular; D017124:Conserved Sequence; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D008969:Molecular Sequence Data; D010766:Phosphorylation; D014176:Protein Biosynthesis; D016601:RNA-Binding Proteins / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D014982:Xenopus laevis / Q000196:embryology / Q000502:physiology*; D039221:mRNA Cleavage and Polyadenylation Factors
chemical_list: D016601:RNA-Binding Proteins; D039221:mRNA Cleavage and Polyadenylation Factors