title: Rapid and sensitive detection of enteroviruses in specimens from patients with aseptic meningitis.
abstract: A 5-h PCR assay (Amplicor enterovirus test) was compared with viral culture for the detection of enteroviruses in cerebrospinal fluid. Of the cerebrospinal fluid specimens collected during a summer outbreak of aseptic meningitis, 34% were positive by viral culture whereas 66% were positive by the Amplicor PCR, suggesting that this technique improves the diagnosis of enteroviral meningitis.
authors: Central Laboratory of Virology, Geneva University Hospital, Switzerland.
authors: S
authors: S
authors: Yerly
authors: A
authors: A
authors: Gervaix
authors: V
authors: V
authors: Simonet
authors: M
authors: M
authors: Caflisch
authors: L
authors: L
authors: Perrin
authors: W
authors: W
authors: Wunderli
mesh_terms: D001483:Base Sequence; D002555:Cerebrospinal Fluid / Q000821:virology; D002648:Child; D017931:DNA Primers / Q000235:genetics; D004196:Disease Outbreaks; D004770:Enterovirus / Q000235:genetics* / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology; D005069:Evaluation Studies as Topic; D006801:Humans; D008582:Meningitis, Aseptic / Q000453:epidemiology / Q000821:virology*; D008587:Meningitis, Viral / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods*; D011446:Prospective Studies; D012367:RNA, Viral / Q000134:cerebrospinal fluid / Q000235:genetics; D014773:Virology / Q000379:methods*; D014776:Virus Cultivation
chemical_list: D017931:DNA Primers; D012367:RNA, Viral