title: Preimplantation genetic testing for Huntington disease and certain other dominantly inherited disorders.
abstract: Preimplantation genetic testing (PGT) on embryos from couples at risk for Huntington disease can achieve disease prevention in offspring without disclosure of parental genotype. This strategy may also be applicable to other extremely deleterious dominant traits.
authors: Genetics & IVF Institute, Fairfax, Virginia 22031, USA.
authors: J D
authors: JD
authors: Schulman
authors: S H
authors: SH
authors: Black
authors: A
authors: A
authors: Handyside
authors: W E
authors: WE
authors: Nance
mesh_terms: D047108:Embryonic Development / Q000235:genetics*; D005260:Female; D005307:Fertilization in Vitro; D005820:Genetic Testing; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis* / Q000235:genetics; D011247:Pregnancy