title: Inner ear malformations in patients with sensorineural hearing loss: detection with gradient-echo (3DFT-CISS) MRI.
abstract: The sensitivity of different MRI sequences in the detection of inner ear malformations in patients presenting with sensorineural hearing loss (SNHL) and/or vertigo was evaluated. We studied 650 patients presenting with SNHL and/or vertigo, clinically not suspected of having inner ear malformations. The sensitivity of T1-weighted, Gd-enhanced T1-weighted and (when available) T2-weighted spin-echo images, and three-dimensional Fourier transformation-constructive interference in steady state (3DFT-CISS) gradient-echo images, to unexpected malformations was assessed. Inner ear malformations were found in 15 (2.3%) of these patients. Enlargement of the endolymphatic duct and sac was the most frequent malformation, found in 11 patients. The 3DFT-CISS images showed all lesions; the other sequences were less sensitive and the pathology was missed, partially or only retrospectively seen in 11 of the 15 patients. Therefore, in addition to the routine unenhanced and Gd-enhanced T1-weighted and T2-weighted images, thin gradient-echo (3DFT-CISS) images are necessary to detect all clinically unexpected inner ear malformations in patients presenting with vertigo and/or SNHL.
authors: Department of Radiology, A. Z. St.-Jan Brugge, Belgium.
authors: J W
authors: JW
authors: Casselman
authors: R
authors: R
authors: Kuhweide
authors: W
authors: W
authors: Ampe
authors: G
authors: G
authors: D'Hont
authors: E F
authors: EF
authors: Offeciers
authors: W K
authors: WK
authors: Faes
authors: G
authors: G
authors: Pattyn
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D000013:Congenital Abnormalities / Q000175:diagnosis; D007758:Ear, Inner / Q000002:abnormalities*; D004711:Endolymphatic Duct / Q000002:abnormalities; D004712:Endolymphatic Sac / Q000002:abnormalities; D005260:Female; D005583:Fourier Analysis; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D014717:Vertigo / Q000175:diagnosis / Q000209:etiology