title: The effect of non-activated prothrombin complex concentrate (Proplex ST) on intraperitoneal hematoma in a hemophilia A patient with a factor VIII inhibitor.
abstract: A 28-year-old severe hemophiliac with a factor VIII inhibitor was admitted to our hospital with a massive and serious intraperitoneal hematoma. He was a high-responder patient showing maximal serum inhibitor levels as high as 255 Bethesda Units/ml (BU/ml). He was successfully treated with "bypass therapy" using a prothrombin complex concentrate (PCC).
authors: First Department of Internal Medicine, Kansai Medical University, Osaka.
authors: H
authors: H
authors: Kagawa
authors: M
authors: M
authors: Yasuzawa
authors: Y
authors: Y
authors: Ozaki
authors: Y
authors: Y
authors: Yamamoto
authors: T
authors: T
authors: Katsurada
authors: S
authors: S
authors: Nomura
authors: S
authors: S
authors: Okubo
authors: S
authors: S
authors: Fukuhara
mesh_terms: D000328:Adult; D001779:Blood Coagulation Factors / Q000627:therapeutic use*; D005169:Factor VIII / Q000037:antagonists & inhibitors; D006406:Hematoma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006467:Hemophilia A / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D010532:Peritoneal Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates; D005169:Factor VIII