Assessment of latex indirect agglutination test (Toxolatex Fumouze) for the detection of Toxoplasma specific antibodies in human sera in Turkey.
Sera from 50 patients were examined with conventional ELISA, IFA and Toxolatex Fumouze. Out of 50 specimens only 3 false positive cases were detected with Toxolatex Fumouze as compared with the results of ELISA & IFA tests. Toxolatex Fumouze represents a rapid, highly sensitive and specific technique for screening of specific antibodies against toxoplasmosis, but due to false negative results, sera from patients at risk of severe toxoplasmosis (fetus, HIV+, transplant, immunosupressed) should be tested with other serological methods such as the dye test, DS-ELISA and ISAGA.
Gürüz
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Department of Parasitology, Faculties of Medicine, Ege University Bornova-Izmir, Turkey.
Ok
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UZ
Korkmaz
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D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005189:False Positive Reactions; D005260:Female; D006679:HIV Seropositivity; D006801:Humans; D007231:Infant, Newborn; D007841:Latex Fixation Tests; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis; D011296:Prenatal Diagnosis; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D014421:Turkey
D000913:Antibodies, Protozoan