title: Improved accuracy of computed tomography in local staging of rectal cancer using water enema.
abstract: A new technique in the preoperative staging computed tomography of rectal cancer using a water enema to promote full distension of the rectum was compared with standard CT in a non-randomised blind study. One hundred and twenty-one patients were enrolled. There were 57 in the water enema CT group and 64 in the standard group. The stage of the disease was assessed following strict criteria and tested against the pathological examination of the resected specimen. Water enema CT was significantly more accurate than standard CT with an accuracy of 84.2% vs. 62.5% (Kappa: 0.56 vs. 0.33: Kappa Weighted: 0.93 vs. 0.84). The diagnostic gain was mainly evident in the identification of rectal wall invasion within or beyond the muscle layer (94.7 vs. 61). The increased accuracy was 33.7% (CL95: 17-49; P < 0.001). The results indicate that water enema CT should replace CT for staging rectal cancer and may offer an alternative to endorectal ultrasound.
authors: Istituto di Clinica Chirurgica, Università di Bari, Italy.
authors: L
authors: L
authors: Lupo
authors: G
authors: G
authors: Angelelli
authors: O
authors: O
authors: Pannarale
authors: D
authors: D
authors: Altomare
authors: L
authors: L
authors: Macarini
authors: V
authors: V
authors: Memeo
mesh_terms: D000328:Adult; D000368:Aged; D004733:Enema; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*