title: [Radiation injuries of the small intestine. Surgical treatment].
abstract: From 1978 to 1992, 55 patients (48 women: 87%) with a mean age of 62 years (35-89) underwent 70 operations for radiation injury of the small bowel. Primary pathology treated with radiotherapy was gynecologic cancer (40: 72%), digestive malignancy (9: 16%), male genital cancer (4: 7%), carcinoma of the bladder (2: 3%). External radiation was performed alone (47: 85.5%) or associated with intracavitary radium or cesium (8: 14.5%), mean radiation dose was 50 Gy for 35 patients and not specified for 20 but greater than 45 Gy for all patients. Fifteen patients had associated chemotherapy. Latent period between radiation injury and first symptoms was 39 months (1-16 years) and 72 months (3-26 years) between radiation and surgical treatment. There were 28 solitary lesions (mean length: 148.5 cm) with 5 associated colonic injuries, 27 multiple lesions of the small bowel (mean length: 187.5 cm) with 21 associated colonic injuries. Twenty-one lesions of the abdominal wall and 13 lesions of the urinary tract were also associated. Nineteen patients had pre-operative total parenteral nutritional assistance. Surgical treatment was performed for chronic obstruction in 46 patients, for fistulae in 5 or for an acute complication in 4 (perforating peritonitis: 3, occlusion: 1). Operations performed were: small bowel resection (32), associated with bypass (2); internal by-pass (15); dissection of adhesions and/or stomy (7).
  
  
  RESULTS
  Operative mortality was 2 (6.2%). Morbidity occurred in 16 (29%) with 3 anastomotic fistulae. Functional results were good for 36 patients (24 resections, 7 by-pass), poor for 2 (1 resection). Failure leading to a second operation occurred in 15 (5 resections, 8 by-pass).
  
  
  CONCLUSIONS
  1) pre-operative nutritional assistance improves operative results; 2) intestinal resection is preferable to internal by-pass whenever it can be performed without extreme risk or unacceptable sequelae.
authors: Service de Chirurgie Générale et Digestive, Université de Paris VI, Hôpital Rothschild, Paris.
authors: P
authors: P
authors: Martel
authors: M
authors: M
authors: Deslandes
authors: L
authors: L
authors: Dugue
authors: A
authors: A
authors: Sezeur
authors: D
authors: D
authors: Gallot
authors: M
authors: M
authors: Malafosse
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D004067:Digestive System Neoplasms / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D005833:Genital Neoplasms, Female / Q000532:radiotherapy / Q000601:surgery; D005834:Genital Neoplasms, Male / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007410:Intestinal Diseases / Q000453:epidemiology / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D007421:Intestine, Small / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011183:Postoperative Complications; D011832:Radiation Injuries / Q000150:complications / Q000453:epidemiology / Q000401:mortality / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies
vernacular_title: Lésions radiques de l'intestin grêle. Traitement chirurgical.