Chronic bullous disease of childhood following Epstein-Barr virus seroconversion: a case report.
We report the case of a 3-year-old boy with classical chronic bullous disease of childhood (CBDC) arising after recent Epstein-Barr virus seroconversion following infectious mononucleosis. The patient also had small red cells and decreased levels of circulating IgA. He received combined treatment with dapsone and prednisone with good results. Our report is the first of CBDC preceded by Epstein-Barr virus seroconversion. The virus may have had an initial immunopathogenic role in the genesis of the bullous eruption.
Baldari
U
U
Department of Dermatology, Giovan Battista Morgagni Hospital, Forli', Italy.
Raccagni
A A
AA
Celli
B
B
Righini
M G
MG
D000890:Anti-Infective Agents / Q000627:therapeutic use; D000914:Antibodies, Viral / Q000097:blood; D002675:Child, Preschool; D002908:Chronic Disease; D003622:Dapsone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D012872:Skin Diseases, Vesiculobullous / Q000150:complications* / Q000188:drug therapy
D000890:Anti-Infective Agents; D000914:Antibodies, Viral; D003622:Dapsone; D011241:Prednisone