title: Stage and developmental specific gene expression during mammalian spermatogenesis.
abstract: Spermatogenesis is a complex developmental process which involves amplification of germinal stem cells, their differentiation into spermatocytes, meiotic division and finally transformation into mature spermatozoa. Therefore, spermatogenesis provides an interesting system for examining the regulation of gene expression during development and differentiation. The genes expressed during spermatogenesis can be divided into two main groups: diploid and haploid expressed genes. In this review, we report about the regulation of expression of a diploid expressed gene, namely the proacrosin gene, and that of a haploid expressed gene, the transition protein 2 gene.
authors: Institute of Human Genetics, University of Göttingen, Germany.
authors: K
authors: K
authors: Nayernia
authors: I
authors: I
authors: Adham
authors: H
authors: H
authors: Kremling
authors: K
authors: K
authors: Reim
authors: M
authors: M
authors: Schlicker
authors: G
authors: G
authors: Schlüter
authors: W
authors: W
authors: Engel
mesh_terms: D000176:Acrosin / Q000235:genetics; D000818:Animals; D001483:Base Sequence; D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics; D018076:DNA, Complementary / Q000235:genetics; D004171:Diploidy; D004792:Enzyme Precursors / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D006238:Haploidy; D006801:Humans; D008297:Male; D011479:Protamines / Q000235:genetics; D014176:Protein Biosynthesis; D013091:Spermatogenesis / Q000235:genetics*
chemical_list: D002868:Chromosomal Proteins, Non-Histone; D018076:DNA, Complementary; D004792:Enzyme Precursors; C082073:PRM1 protein, human; D011479:Protamines; C068621:protamine 2; C053886:spermatid transition proteins; C022438:proacrosin; D000176:Acrosin