The role of computerized morphometric and cytometric feature analysis in endometrial hyperplasia and cancer prognosis.
In our hospital, quantitative cell and tissue analysis is routinely applied in endometrial (pre)malignancies. Reasons for this are higher accuracy, reproducibility and objectivity when compared to subjective assessment of type and grade, the possibility of detecting changes and differences, and better compatibility with clinical requests (two-class instead of three- or four-class system). Furthermore, prognostication is at least a good or better than with the usual subjective methods. Clinical prospective intervention trials are currently being set up.
Baak
J P
JP
Institute for Pathology, Free University Hospital, Amsterdam, The Netherlands.
D002986:Clinical Trials as Topic; D003581:Cytodiagnosis; D004714:Endometrial Hyperplasia / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D011237:Predictive Value of Tests; D011379:Prognosis; D012680:Sensitivity and Specificity