Post-operative pain relief in children following caudal bupivacaine and buprenorphine--a comparative study.
Eighty-five paediatric patients (age range: 6 mths-12yrs) undergoing lower abdominal surgery were studied for post-operative pain relief following either caudal bupivacaine (GpI: n = 43) or buprenorphine (GpII: n = 42). Bupivacaine was administered as 0.5ml/kg body weight of 0.25% solution and buprenorphine as 4 micrograms/ml and volume of 0.5 ml/Kg body weight in normal saline. Post-operatively pain was graded on a 4-point scale and behaviour on a 5-point scale. Any post-operative complications and need for additional analgesia were also noted. Bupivacaine provided good pain relief in the early post-operative hours but buprenorphine provided pain relief lasting for 24 hrs or more post-operatively. Post-operative behaviour of 10 patients receiving buprenorphine was graded as cheerful as compared to 2 from bupivacaine group. Till the end of observation period (i.e. 8 hr post-operatively), majority of patients receiving buprenorphine remained cheerful.
Anilkumar
T K
TK
Dept of Anaesthesiology, KEM Hospital, Parel, Bombay.
Karpurkar
S A
SA
Shinde
V S
VS
D000701:Analgesics, Opioid / Q000494:pharmacology / Q000627:therapeutic use*; D000763:Anesthesia, Caudal; D000779:Anesthetics, Local / Q000494:pharmacology / Q000627:therapeutic use*; D002045:Bupivacaine / Q000494:pharmacology / Q000627:therapeutic use*; D002047:Buprenorphine / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007194:India; D007223:Infant; D010149:Postoperative Pain / Q000188:drug therapy*
D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D002047:Buprenorphine; D002045:Bupivacaine