From physiology to clinics--20 years of experience with pulsatile GnRH.
The physiological and the pathophysiological basis of unvariant pulsatile administration of gonadotrophin-releasing hormone (GnRH) as well as the clinical results are reviewed. Pulsatile administration of GnRH not only proved to be a very effective treatment mode but also became an important tool for research in the central control of pituitary and ovarian function under normal and disease conditions.
Leyendecker
G
G
Frauenklinik des Klinikum Darmstadt, Academic Teaching Hospital, University of Frankfurt, Germany.
Wildt
L
L
D000568:Amenorrhea / Q000628:therapy*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage* / Q000502:physiology; D006801:Humans; D017588:Hyperandrogenism / Q000628:therapy*; D012106:Research
D007987:Gonadotropin-Releasing Hormone