[Diagnosis of meconium aspiration syndrome by fluorometry technique].
OBJECTIVE
To establish a new diagnostic method of neonatal meconium aspiration syndrome (MAS).


METHODS
The fluorometry technique was used for examination of urine samples from three groups of neonates. The neonates were divided into 3 groups: Group I, MAS (n = 17); Group II, no MAS, but amniotic fluid with meconium stain (n = 24); Group III, normal control (n = 27). Urine fluorescence meconium index (UFMI) and urine meconium index (UMI) were calculated.


RESULTS
UFMI values of group I were higher than that of group II and III. The sensitivity and specificity of UFMI were 100% and 97% respectivety. However, it were 51% and 48% respectivety in UMI.


CONCLUSIONS
UFMI is an index for identification of Zn-coproporphycin, and it is a more sensitive index for diagnosis of MAS.
Zang
C
C
Second Clinical Hospital, Bethune University of Medical Science, Changchun.
Yu
S
S
Li
S
S
D003306:Coproporphyrins / Q000032:analysis; D005260:Female; D005470:Fluorometry; D006801:Humans; D007231:Infant, Newborn; D008471:Meconium Aspiration Syndrome / Q000175:diagnosis* / Q000652:urine; D015032:Zinc / Q000032:analysis
D003306:Coproporphyrins; C031467:coproporphyrin I; D015032:Zinc