title: Measurement of regional aortic compliance by MR imaging: a study of reproducibility.
abstract: The reproducibility of MR imaging for the measurement of aortic compliance was studied in 47 healthy volunteers. Long and short term reproducibility and intraobserver variability were tested. The method was modified to improve image quality and short term reproducibility and intraobserver variability retested. For comparison, spin echo imaging was compared with cine gradient echo imaging. Initial long term reproducibility showed a mean difference (+/-SE) of 3% (+/- 7%) with 95% confidence interval (CI) for limits of agreement of +/- 69%. Short term reproducibility (7% +/- 6%, 95% CI +/- 46%) and intraobserver variability (1% +/- 2%, 95% CI +/- 31%) were better. After modification of the technique and optimization of image quality, both short term reproducibility and intraobserver variability improved (0% +/- 3%, 95% CI +/- 17% and 5% +/- 2%, 95% CI +/- 16% respectively). Aortic compliance can be measured using spin echo MR imaging with good reproducibility provided care is taken to obtain good quality images with high spatial resolution.
authors: Royal Brompton Hospital, London, UK.
authors: S M
authors: SM
authors: Forbat
authors: R H
authors: RH
authors: Mohiaddin
authors: G Z
authors: GZ
authors: Yang
authors: D N
authors: DN
authors: Firmin
authors: S R
authors: SR
authors: Underwood
mesh_terms: D000328:Adult; D000368:Aged; D001011:Aorta / Q000502:physiology*; D003187:Compliance; D017352:Echo-Planar Imaging / Q000295:instrumentation; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D018810:Magnetic Resonance Angiography / Q000295:instrumentation*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D019028:Magnetic Resonance Imaging, Cine / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D015203:Reproducibility of Results; D014655:Vascular Resistance / Q000502:physiology*