title: Endoscopic hemostasis of upper gastrointestinal bleeding with histoacryl: last resort before surgery.
abstract: Five patients presented with acute upper gastrointestinal bleeding, underwent diagnostic and therapeutic endoscopy. The source of bleeding was identified in each case. Two patients had a large chronic gastric ulcer, one had a stress ulcer, one had a gastric ulcer with hypertrophic gastropathy, and one had a malignant infiltration of the second part of the duodenum. Conventional first-line therapeutic modalities failed to induce hemostasis in these bleeding lesions. Hemostasis was successfully achieved in each case using an endoscopic intralesional injection of Histoacryl. This agent may represent a last resort for endoscopic hemostasis before surgery.
authors: Department of surgery, National University Hospital, Singapore.
authors: K Y
authors: KY
authors: Yok
authors: C K
authors: CK
authors: Kum
authors: P M
authors: PM
authors: Goh
mesh_terms: D000368:Aged; D004659:Enbucrilate / Q000627:therapeutic use*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D016558:Hemostasis, Endoscopic / Q000379:methods*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D015911:Sclerotherapy / Q000379:methods*; D013276:Stomach Ulcer / Q000150:complications
chemical_list: D004659:Enbucrilate