title: [Aortic valve replacement with pericardial bioprosthesis in patients under 60 years of age. Experience over 10 years].
abstract: Between July 1984 and December 1993. 110 patients, younger than 60 years, underwent aortic valve replacement with a Carpentier-Edwards pericardial valve. 75.5% were male, with a mean age of 49.6 years (range: 16 to 59 years). Mean clinical status was 2.25. Operative mortality was 0%. All patients but 3 were followed up with a total follow-up of 454 patient-years and an average of 4.8 years. The 10-year actuarial survival is 91 +/- 6%. We observed 8 valve-related complications (1.7% patient-years): 3 cases of endocarditis, 3 structural failures, 1 thromboembolic event, and 1 perivalvular leak. 1 patient died from a valve-related cause, and 2 reoperations were necessary. The 8-year actuarial probability of absence of valve-related death is 99 +/- 1%, thromboembolism 98 +/- 2%, endocarditis 96 +/- 4%; reoperations 96 +/- 4%, and valve failure 97 +/- 3%. The 10-year valve-related complication rate is satisfactory, but the durability of the prosthesis in this group of young patients remains unknown. A longer follow-up is mandatory to draw definitive conclusions.
authors: Unité de Chirurgie Cardiaque, Hôpital Trousseau, TøURS.
authors: M
authors: M
authors: Aupart
authors: S
authors: S
authors: Hammami
authors: A
authors: A
authors: Sirinelli
authors: X
authors: X
authors: Dreyfus
authors: Y
authors: Y
authors: Meurisse
authors: M
authors: M
authors: Marchand
mesh_terms: D000206:Actuarial Analysis; D000293:Adolescent; D000328:Adult; D001021:Aortic Valve; D001705:Bioprosthesis; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000637:transplantation*; D012086:Reoperation; D012189:Retrospective Studies; D014182:Transplantation, Autologous
vernacular_title: Le remplacement valvulaire aortique par bioprothèses péricardiques à moins de 60 ans. Expérience de 10 ans.