title: [Functional magnetic resonance imaging of the frontal eye fields during saccadic eye movements].
abstract: We evaluated activity-induced signal intensity changes in the human cerebral cortex during horizontal saccadic eye movements using functional magnetic resonance imaging (fMRI) based on the blood-oxygenation-level-dependent (BOLD) contrast method. Compared with central fixation, significant signal increases were observed bilaterally in the middle frontal gyrus (Brodmann area 8) during saccadic conditions. The location of the activated area was consistent with that of previously reported frontal eye fields (FEF). These results suggest that fMRI has potential merit for the study of cortical control of eye movements in humans.
authors: Department of Ophthalmology, Niigata University School of Medicine, Japan.
authors: A
authors: A
authors: Miki
authors: T
authors: T
authors: Nakajima
authors: S
authors: S
authors: Miyauchi
authors: M
authors: M
authors: Takagi
authors: H
authors: H
authors: Abe
mesh_terms: D000328:Adult; D005260:Female; D005625:Frontal Lobe / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009799:Ocular Physiological Phenomena; D012438:Saccades; D014794:Visual Fields / Q000502:physiology*