[Rôle of growth hormone therapy in the genesis of slipped capital femoral epiphysis].
The authors report two cases of children treated with growth hormone who had a secondary slipped capital femoral epiphysis. Endocrine disease, radiotherapy are some well-known etiological factors reported in literature, but growth hormone influence is still discussed. This hormone could have an indirect incidence on this pathology because of its effects on growth cartilage. The increased number of treatment with growth hormone is certainly a risk factor for slipped capital femoral epiphysis. Regular checking from "France Hypophyse" allows an early diagnosis of epiphysis and surgical fixation can be made immediately. Systematic controlateral side fixation it still discussed but allowed to continue the treatment with the same posology.
Reynaud
P
P
Service de Chirurgie et Orthopédie pédiatrique, Hôpital Edouard Herriot, Lyon.
Kohler
R
R
D000293:Adolescent; D001863:Bone Screws; D002675:Child, Preschool; D004392:Dwarfism / Q000188:drug therapy; D004839:Epiphyses, Slipped / Q000139:chemically induced* / Q000503:physiopathology / Q000601:surgery; D005270:Femur Head; D013006:Growth Hormone / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male
D013006:Growth Hormone
Rôle du traitement par hormone de croissance dans la genèse de l'épiphysiolyse fémorale supérieure.