title: [Systen--transdermal estradiol for substitution following surgical menopause].
abstract: The authors investigate the clinical effect of transdermal system delivering 17 beta-estradiol for treatment of 23 patients after bilateral ovariectomy for benign genital tumors. During four to six months treatment Kuppermann index falls and karyopyknotic and maturation indices rise significantly. The side effects are extremely rare. The authors recommend the widely use of Systen for replacement therapy in surgically induced menopause.
authors: E
authors: E
authors: Rachev
authors: I
authors: I
authors: Karag'ozov
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D004341:Drug Evaluation; D004958:Estradiol / Q000008:administration & dosage*; D015914:Estrogen Replacement Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010052:Ovariectomy; D011182:Postoperative Care / Q000379:methods*
chemical_list: D004958:Estradiol
vernacular_title: Systen--transdermalen estradiol za substitutsiia sled khirurgichna menopauza.