Molecular chaperones and disease.
Molecular chaperones are intracellular protein-folding proteins which form part of an ancient cellular response to stress called the heat shock response. They have been the focus for attention during the last decade because of the discovery of their vital role in cell functioning. In very recent years additional roles for these 'topologically-active' proteins in the process of tissue pathology and its treatment have been indicated and are reviewed.
Henderson
B
B
Maxillofacial Surgery Research Unit, Eastman Dental Institute for Oral Health Care Sciences, University College London, UK.
Nair
S P
SP
Coates
A R
AR
D002477:Cells / Q000166:cytology / Q000378:metabolism; D006706:Homeostasis; D006358:Hot Temperature; D018832:Molecular Chaperones / Q000276:immunology / Q000502:physiology* / Q000627:therapeutic use; D008970:Molecular Weight
D018832:Molecular Chaperones