title: Canine infectious cyclic thrombocytopenia found in Taiwan.
abstract: Here were report the first canine infectious cyclic thrombocytopenia (CICT) found in Taiwan. Platelet-specific inclusions were detected in the blood smear of a military working dog. To identify the etiologic agent, the patient's blood was transmitted to three six-month-old German Shepherd dogs. The Ehrlichia platys-like inclusions were observed six to eight days after inoculation. Indirect fluorescent antibody test showed that the serum from the patient reacted specifically with the microorganisms within the platelets. Typical hematologic manifestations of E. platys infection, cyclic parasitemia and concomitant thrombocytopenia, were observed in these dogs. The prevalence of CICT in north Taiwan was also studied, and the incidence was 8.9% (4 out of 45) in civilian dogs and 97.1% (34 out of 35) in dogs from a heavily tick infested kennel.
authors: Institute of Biological Chemistry, Academia Sinica, National Taiwan University, Taipei, Taiwan.
authors: A C
authors: AC
authors: Chang
authors: W L
authors: WL
authors: Chang
authors: C T
authors: CT
authors: Lin
authors: M J
authors: MJ
authors: Pan
authors: S C
authors: SC
authors: Lee
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000382:microbiology; D004283:Dog Diseases; D004285:Dogs; D004536:Ehrlichia / Q000302:isolation & purification; D016873:Ehrlichiosis / Q000097:blood / Q000662:veterinary*; D019084:Fluorescent Antibody Technique, Indirect; D008297:Male; D010976:Platelet Count; D013156:Splenectomy; D013624:Taiwan; D013921:Thrombocytopenia / Q000097:blood / Q000382:microbiology / Q000662:veterinary*