title: Distribution of enteric neural peptide YY in the dog gastrointestinal tract.
abstract: Various regions of the dog gastrointestinal tract were investigated for the distribution of peptide YY (PYY) neurons using immunocytochemistry and radioimmunoassay. PYY neurons that encircled non-PYY-immunoreactive neurons were mainly observed in the myenteric plexus from the stomach to the colon. There was more PYY-like immunoreactivity in the muscle layer of the stomach and ileum than in the other intestines. The results of high performance liquid chromatography revealed that neural PYY-immunoreactive substance is identical to authentic PYY. PYY was not localized in the cholinergic neurons. These results indicate that PYY, as a neuropeptide, is involved in the regulation of gastrointestinal function.
authors: Gastrointestinal Research Laboratory, Gunma University, Japan.
authors: K
authors: K
authors: Iesaki
authors: T
authors: T
authors: Sakai
authors: M
authors: M
authors: Satoh
authors: N
authors: N
authors: Haga
authors: H
authors: H
authors: Koyama
authors: Z
authors: Z
authors: Itoh
mesh_terms: D000818:Animals; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D004064:Digestive System / Q000294:innervation / Q000378:metabolism*; D004068:Digestive System Physiological Phenomena; D004285:Dogs; D017615:Enteric Nervous System / Q000378:metabolism*; D005260:Female; D005768:Gastrointestinal Hormones / Q000378:metabolism* / Q000502:physiology; D007150:Immunohistochemistry; D008297:Male; D009197:Myenteric Plexus / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D019894:Peptide YY; D010455:Peptides / Q000378:metabolism* / Q000502:physiology; D014018:Tissue Distribution
chemical_list: D005768:Gastrointestinal Hormones; D010455:Peptides; D019894:Peptide YY; D002795:Choline O-Acetyltransferase