Apoptosis in the rostral migratory stream of the developing rat.
The rostral migratory stream consists of a large number of cells migrating from the lateral ventricles to the rostral telencephalon, primarily the olfactory bulb. The pathway continually provides neuro- and glioblasts throughout life. The present paper indicates that a considerable number of cells undergo apoptotic cell death en route, even in young (day 3) rats when presumably many vacant sites are still available in the developing brain.
Brunjes
P C
PC
Department of Psychology, University of Virginia, Charlottesville 22903, USA. brunjes@virginia.edu
Armstrong
A M
AM
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002552:Cerebral Ventricles / Q000166:cytology* / Q000254:growth & development / Q000502:physiology; D009830:Olfactory Bulb / Q000166:cytology / Q000254:growth & development / Q000502:physiology; D051381:Rats; D013687:Telencephalon / Q000166:cytology* / Q000254:growth & development / Q000502:physiology