title: A new type of cell death, the protruded type, observed in the adrenal gland of normal rats.
abstract: Apart from apoptosis, a type of parenchymal cell death by the cell protruding into the capillary lumen was observed in the adrenal gland of normal Sprague-Dawley rats. Ultrathin sections were prepared in the conventional manner and were examined by electron microscopy. The protruded cells (p-cells) had the electron lucent cytoplasm and the p-cells with ruptured cell membranes were observed in the capillaries. The egress of p-cells was either through the endothelial gaps, or following the rupture of capillary endothelia. The cytoplasmic matrices of the dying p-cells were seen to scatter in the capillary lumen where the nuclei, mitochondria and granules remained morphologically intact. The p-cells were seen in the capillaries of medulla, but restricted to those of zona reticularis in the cortex.
authors: Research Institute for Animal Science in Biochemistry and Toxicology, Kanagawa, Japan.
authors: C
authors: C
authors: Chen-Pan
authors: Y
authors: Y
authors: Yamamoto
authors: Y
authors: Y
authors: Ito
authors: I J
authors: IJ
authors: Pan
authors: Y
authors: Y
authors: Hayashi
mesh_terms: D000302:Adrenal Cortex / Q000502:physiology / Q000648:ultrastructure; D000311:Adrenal Glands / Q000502:physiology / Q000648:ultrastructure*; D000313:Adrenal Medulla / Q000098:blood supply / Q000502:physiology / Q000648:ultrastructure; D000818:Animals; D017209:Apoptosis; D001343:Autophagy; D002196:Capillaries; D016923:Cell Death; D002462:Cell Membrane / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000648:ultrastructure; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D014617:Vacuoles / Q000648:ultrastructure; D015385:Zona Reticularis / Q000502:physiology / Q000648:ultrastructure