title: MR measurement of time-dependent blood pressure variations.
abstract: An MR imaging method for measuring intravascular pressure variations is introduced. The technique is based on estimates of vascular compliance and vessel distension, which are obtained from a correlation of spatial and temporal velocity derivatives and measurements of the velocity gradient in the direction of flow, respectively. The accuracy of the technique was determined in vitro through a comparison of MR and transducer pressure measurements obtained in distensible vessel phantoms undergoing pulsatile flow. Results indicated that a root-mean-square error of 4-12% can be expected in phantoms covering a physiological range of compliance. In vivo feasibility was demonstrated by thoracic aorta pressure measurements, which produced pressure waveforms with an expected shape and magnitude.
authors: Department of Medical Biophysics, University of Toronto, Ontario, Canada.
authors: S N
authors: SN
authors: Urchuk
authors: D B
authors: DB
authors: Plewes
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D003187:Compliance; D005240:Feasibility Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D018810:Magnetic Resonance Angiography / Q000295:instrumentation*; D008297:Male; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D009131:Muscle, Smooth, Vascular / Q000502:physiology; D012016:Reference Values; D014160:Transducers, Pressure