[Effects of total saponins of semen ziziphi Spinosae on brain damages and brain biochemical parameters under cerebral ischemia of rats].
Total saponins of Semen Ziziphi Spinosae (ZS) can reduce the contents of water and MDA in ischemic rat's brain tissues, elevate the activity of SOD, CK and LDH, cut down the content of lactate and alleviate the damages of nerve cells in brain. The study shows that ZS possesses protective effects on cerebral ischemic injuries.
Bai
X
X
First Military Medical University, Guangzhou.
Huang
Z
Z
Mo
Z
Z
Pan
H
H
Ding
H
H
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000648:ultrastructure; D002545:Brain Ischemia / Q000378:metabolism* / Q000473:pathology; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D005260:Female; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007773:Lactates / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*
D004365:Drugs, Chinese Herbal; D007773:Lactates; D012503:Saponins; D008315:Malondialdehyde; D007770:L-Lactate Dehydrogenase