[Evaluation of the effectiveness of immunomodulators in the treatment of patients with postoperative suppurative-septic complications].
The influence of immunoactive medicines on the cell immunity have been studied. There were differences in reaction to T-activin and Thymalin between various patients with septic postoperative complications. Thymalin stimulated T-cells while acting with immunoglobulins or immune plasmas only. T-activin led to the increase in the number of T-lymphocytes and B-lymphocytes independently of it's cooperation with the vaccines. The stimulating effect of myelopid demonstrated itself by increase in the number of B-lymphocytes and immunoglobulins M and G after 14 days of treatment. The positive clinical effect was more impressive when immunomodulators were used in combinations with the vaccines; still it did not correlate completely with the dynamics of the cell immunity parameters.
Bulava
G V
GV
Nikulina
V P
VP
D028341:Activins; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D001853:Bone Marrow; D016724:Empyema, Pleural / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D016131:Lymphocyte Subsets; D009842:Oligopeptides; D010019:Osteomyelitis / Q000188:drug therapy* / Q000276:immunology; D010455:Peptides / Q000627:therapeutic use; D010538:Peritonitis / Q000188:drug therapy* / Q000276:immunology; D010587:Phagocytosis; D011183:Postoperative Complications / Q000188:drug therapy*; D013492:Suppuration; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000276:immunology; D013949:Thymus Extracts / Q000627:therapeutic use; D013951:Thymus Hormones / Q000627:therapeutic use; D013997:Time Factors
D000276:Adjuvants, Immunologic; D007136:Immunoglobulins; D009842:Oligopeptides; D010455:Peptides; D013949:Thymus Extracts; D013951:Thymus Hormones; C044147:activin B; D028341:Activins; C048617:myelopeptides; C032805:thymalin; C036191:T-activin
Otsenka éffektivnosti immunomoduliatorov pri lechenii bol'nykh s gnoĭno-septicheskimi posleoperatsionnymi oslozhneniiami.