Perceptual studies in patients with vestibular neurectomy.
Twelve patients undergoing unilateral vestibular neurectomy for the treatment of refractory vertigo were investigated. Vestibular motion perception was assessed using a self-rotational task and "vestibular remembered saccades". Cervical perception was also measured with remembered saccades. The tests were performed pre- and post-operatively to examine changes in vestibular and cervical perception following an acute vestibular lesion, and to monitor the progress of vestibular compensation. These perception tests were carried out in conjunction with a conventional evaluation of the vestibular ocular reflex (VOR), using electro-oculography. The patients' subjective symptoms at each stage of testing were also quantified with questionnaires. Generally, in the vestibular tests, for stimulation to the operated side, responses became strongly hypometric directly after the neurectomy, with a partial recovery during convalescence. In the cervical test, responses were bilaterally reduced immediately after operation. Results from both of the vestibular perception tests were significantly correlated with the VOR assessment of vestibular function. Scores for the patients' subjective symptoms of "vertigo" were only significantly correlated with the vestibular perception tests, and not with the conventional measures of vestibular function. Perceptual measurements afford useful complementary information in the assessment of vestibular patients.
Kanayama
R
R
MRC, Human Movement and Balance Unit, National Hospital for Neurology and Neurosurgery, London, England.
Bronstein
A M
AM
Gresty
M A
MA
Brookes
G B
GB
Faldon
M E
ME
Nakamura
T
T
D000328:Adult; D004585:Electrooculography; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007699:Kinesthesis / Q000502:physiology; D008297:Male; D008575:Meniere Disease / Q000601:surgery*; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D009334:Neck Muscles / Q000294:innervation*; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology*; D011434:Proprioception / Q000502:physiology*; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology; D012399:Rotation; D012438:Saccades / Q000502:physiology*; D016896:Treatment Outcome; D014724:Vestibular Function Tests; D014725:Vestibular Nerve / Q000503:physiopathology / Q000601:surgery*