[Acute lymphoblastic leukemia with L1 morphology arising during treatment for ALL-L3 in a child with AIDS].
A child with AIDS is presented who developed L1-ALL while being treated for L3-AL. After achievement of complete remission of the former, he suffered a relapse with L3 morphology. Although the possibilities of a shift in both the morphology and the immunophenotype of ALL in relapse are well known, the rarity of L1-ALL in association with AIDS is stressed by the authors, along with the factors related with the morphologic and phenotypic changes shown by these patients.
Fernández-Teijeiro
A
A
Unidad de Oncología Pediátrica, Hospital de Cruces-Baracado, Vizcaya.
Piñán
M A
MA
Cardenal
I
I
Astigarraga
I
I
Navajas
A
A
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D002051:Burkitt Lymphoma / Q000097:blood / Q000150:complications* / Q000473:pathology; D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D016130:Immunophenotyping; D008297:Male; D016609:Neoplasms, Second Primary / Q000097:blood / Q000473:pathology; D014411:Neoplastic Stem Cells / Q000276:immunology / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000150:complications* / Q000473:pathology; D015215:Zidovudine / Q000627:therapeutic use
D015215:Zidovudine
Leucemia linfoblástica aguda (LLA) con morfología L1 de aparición durante el tratamiento de LLA-L3 en niño con SIDA.