[Multiple digestive involvement in visceral leishmaniasis in a patient with HIV infection: favourable course with itraconazole].
We report a case of visceral leishmaniasis due to Leishmania infantum in a 35 year-old patient with acquired immunodeficiency syndrome who complained of chronic diarrhea. Biopsy specimens of gastric and duodenal mucosa and bone marrow aspirate led to the diagnosis. Enterocytozoon bieneusi, fortuitously found in the duodenal mucosa, did not seem to be the causative agent of diarrhea in this case, but its association with visceral leishmaniasis is rare. A treatment with itraconazole brought about a sustained clinical remission.
Béchade
D
D
Service de médecine interne et d'hématologie, HIA Robert Picqué, Bordeaux-Armées, France.
Seurat
L
L
Discamps
G
G
Tanière
P H
PH
Du Bourguet
F
F
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000328:Adult; D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use*; D004066:Digestive System Diseases / Q000188:drug therapy / Q000469:parasitology*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D018314:Leishmania infantum; D007898:Leishmaniasis, Visceral / Q000188:drug therapy / Q000209:etiology*; D008297:Male
D000935:Antifungal Agents; D017964:Itraconazole
Atteinte digestive multiple au cours d'une leishmaniose viscérale chez un patient infecté par le VIH: évolution favorable sous itraconazole.