Immune response to Shigella sonnei in U.S. Marines.
Pre- and postdeployment serum samples obtained from U.S. marines in Operations Desert Shield and Desert Storm were tested for antibodies to Shigella sonnei. High predeployment levels of immunoglobulin A (IgA) and/or IgG antibodies to S. sonnei lipopolysaccharide antigen in serum and seroconversions were accompanied by higher IgA and/or IgG antibody response to Shigella invasion plasmids (Ipa). The results suggest exposure to S. sonnei in predeployment troops and frequent exposure to this bacterial agent during deployment.
Mikhail
M M
MM
U.S. Naval Medical Research Unit No. 3, Cairo, Egypt.
Mansour
M M
MM
Oyofo
B A
BA
Malone
J D
JD
D000907:Antibodies, Bacterial / Q000276:immunology*; D000942:Antigens, Bacterial / Q000737:chemistry / Q000276:immunology*; D015153:Blotting, Western; D004405:Dysentery, Bacillary / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D008887:Military Medicine; D008889:Military Personnel; D012764:Shigella sonnei / Q000276:immunology*; D012995:Solubility
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G