The role of HMT (histamine N-methyltransferase) in airways: a review.
Histamine N-methyltransferase (HMT) expressed in the epithelial and endothelial cells of the airways is a principal enzyme degrading histamine in the body. This brief review summarizes the recent advances in molecular biology related to the pathophysiological role of HMT in regulating airway functions.
Okinaga
S
S
Department of Geriatric Medicine, Tohoku University School of Medicine,Sendai City, Japan.
Ohrui
T
T
Nakazawa
H
H
Yamauchi
K
K
Sakurai
E
E
Watanabe
T
T
Sekizawa
K
K
Sasaki
H
H
D000818:Animals; D001980:Bronchi / Q000201:enzymology*; D003001:Cloning, Molecular; D006632:Histamine / Q000378:metabolism; D006637:Histamine N-Methyltransferase / Q000235:genetics / Q000502:physiology*; D006801:Humans; D012141:Respiratory Tract Infections / Q000201:enzymology; D014132:Trachea / Q000201:enzymology*; D014777:Virus Diseases / Q000201:enzymology
D006632:Histamine; D006637:Histamine N-Methyltransferase