title: Identification of a glutathione peroxidase homolog in Neisseria meningitidis.
abstract: Glutathione peroxidase is an antioxidant enzyme found in a diverse array of eukaryotic species. We have determined the DNA sequence of a glutathione peroxidase homolog in the pathogenic bacterium Neisseria meningitidis. The sequence displays features of a functional gene, but lacks a selenocysteine-encoding in-frame TGA codon characteristic of most mammalian glutathione peroxidase genes. The derived amino acid sequence encoded by the N. meningitidis homolog predicts a 19.9 kDa protein that displays a high level of amino acid identity with other gluathione peroxidase sequences, particularly within four conserved regions of the enzyme.
authors: Department of Biology, Concordia College, Moorhead, Minnesota, USA, 56562.
authors: E L
authors: EL
authors: Aho
authors: L P
authors: LP
authors: Kelly
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D005979:Glutathione Peroxidase / Q000235:genetics*; D008969:Molecular Sequence Data; D009345:Neisseria meningitidis / Q000235:genetics*; D017385:Sequence Homology
chemical_list: D005979:Glutathione Peroxidase