Relationship between optic nerve head parameters of Heidelberg Retina Tomograph and visual field defects in primary open-angle glaucoma.
To investigate the correlation between optic nerve head configuration and visual field defects, optic nerve head analysis using confocal scanning laser tomography (Heidelberg Retina Tomograph, HRT) and automated static threshold perimetry using a Humphrey Field Analyzer (program C30-2) were performed on 81 eyes of 44 primary open-angle glaucoma (POAG) patients. The optic nerve head parameters-rim area, rim volume, mean retinal nerve fiber layer thickness, height variation contour, and third moment in contour were measured by HRT and were analyzed for correlation with visual field indices-mean deviation, and corrected pattern standard deviation. All optic nerve head parameters except HVC correlated significantly with the visual field indices; the highest correlation was between rim area and mean deviation (r = 0.6172, p < 0.00001). The rim area of the superior and inferior quadrants correlated significantly with the visual field defects in corresponding sectors. Structural optic disc measurements by HRT correlated significantly with functional optic nerve head damage in POAG.
Lee
K H
KH
Department of Ophthalmology, College of Medicine, Seoul National University, Korea.
Park
K H
KH
Kim
D M
DM
Youn
D H
DH
D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology; D009898:Optic Disk / Q000473:pathology* / Q000503:physiopathology; D012160:Retina / Q000473:pathology; D014054:Tomography / Q000379:methods*; D014786:Vision Disorders / Q000473:pathology* / Q000503:physiopathology; D058609:Visual Field Tests; D014794:Visual Fields