Single electrical shock of a somatic afferent nerve elicits A- and C-reflex discharges in gastric vagal efferent nerves in anesthetized rats.
The possibility that single electrical shock stimulation of somatic afferent nerves could evoke a reflex response in vagal efferent nerves innervating the stomach was examined using anesthetized, artificially-ventilated rats. A single shock to a hindlimb afferent nerve (tibial nerve) produced two distinct reflex components in gastric vagal efferent nerves; namely (1) A-reflex discharges with a latency of about 120 ms and a duration of about 200 ms elicited by stimulation of myelinated A afferent fibers, and (2) C-reflex discharges with a latency of about 360 ms and a duration of about 200 ms elicited by stimulation of unmyelinated C afferent fibers. A single shock to a first lumbar spinal afferent nerve produced only a week reflex component with a latency of about 120 ms and a duration of about 190 ms in gastric vagal efferent nerves. Limb afferents appear to have stronger central pathways functionally connecting to gastric vagal efferent preganglionic neurons in the brainstem, than do abdominal afferents.
Kimura
A
A
Department of the Autonomic Nervous System, Tokyo Metropolitan Institute of Gerontology, Japan.
Sato
A
A
Sato
Y
Y
Suzuki
A
A
D000758:Anesthesia; D000818:Animals; D003714:Denervation; D004558:Electric Stimulation; D008297:Male; D009475:Neurons, Afferent / Q000502:physiology*; D009476:Neurons, Efferent / Q000502:physiology*; D009619:Nociceptors / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D012018:Reflex / Q000502:physiology*; D013270:Stomach / Q000294:innervation; D013979:Tibial Nerve / Q000601:surgery; D014630:Vagus Nerve / Q000166:cytology* / Q000502:physiology