Structural studies of mitomycins. VII. Mitomycin G.
The title compound, [1aS-(1a alpha, 8a alpha, 8b alpha)]-6-amino-1, 1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-8-methyleneazirino [2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, C15H17N3O3, is a derivative of the mitomycins, which are antitumor antibiotics. The quinone O atoms deviate significantly from the least-squares plane of the quinone ring.
Hirayama
N
N
Department of Biological Science and Technology, Tokai University, Shizouka, Japan.
Arai
H
H
Kasai
M
M
D000903:Antibiotics, Antineoplastic / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D007211:Indoles / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D011809:Quinones / Q000737:chemistry
D000903:Antibiotics, Antineoplastic; D007211:Indoles; D011809:Quinones; C101072:mitomycin G