Diagnostic value of electron microscopy in rare malignant musculoskeletal tumors. Experience from an orthopedic tumor center.
Rare musculoskeletal tumors can be difficult to diagnose by light microscopy or immunohistochemistry. Electron microscopy can be of diagnostic assistance especially if histotype specific ultrastructural features exist. In particular, electron microscopy for uncommon sarcomas such as alveolar soft part sarcoma, parachordoma, atypical Ewing's sarcoma and epithelioid sarcoma may be the diagnostic modality of choice.
Carlén
B
B
Department of Pathology, University Hospital, Lund University, Sweden.
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001707:Biopsy, Needle; D001859:Bone Neoplasms / Q000175:diagnosis*; D002648:Child; D002817:Chordoma / Q000175:diagnosis; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000175:diagnosis*; D012509:Sarcoma / Q000175:diagnosis* / Q000648:ultrastructure; D018234:Sarcoma, Alveolar Soft Part / Q000175:diagnosis / Q000648:ultrastructure; D012512:Sarcoma, Ewing / Q000175:diagnosis / Q000648:ultrastructure
D014408:Biomarkers, Tumor