title: Linear scleroderma in children.
abstract: BACKGROUND
  Linear scleroderma is a cutaneous disease of unknown etiology. It most often affects children, who develop band-like lesions in an asymmetric distribution. The literature is reviewed as to the diagnosis, pathogenesis, and treatment of linear scleroderma.
  
  
  METHODS
  Six new cases of linear scleroderma in children are reported. Their ages ranged from 6 to 17 years, and five were girls. A 17-year-old girl had en coup de sabre. Multiple treatment modalities were used. All laboratory testing was negative.
  
  
  CONCLUSIONS
  Linear scleroderma is a clinical diagnosis. The pathogenesis remains unknown. A consistently effective therapy has not been found, although diphenylhydantoin and ticlopidine hydrochloride should be evaluated in clinical trials.
authors: Department of Dermatology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
authors: L E
authors: LE
authors: Eubanks
authors: E I
authors: EI
authors: McBurney
authors: W
authors: W
authors: Galen
authors: R
authors: R
authors: Reed
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D001623:Betamethasone / Q000031:analogs & derivatives / Q000627:therapeutic use; D002648:Child; D003879:Dermatologic Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D010672:Phenytoin / Q000627:therapeutic use; D012594:Scleroderma, Localized / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D013988:Ticlopidine / Q000627:therapeutic use; D014810:Vitamin E / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D003879:Dermatologic Agents; D005938:Glucocorticoids; D010406:Penicillins; D014810:Vitamin E; D010672:Phenytoin; C011175:betamethasone-17,21-dipropionate; D001623:Betamethasone; D013988:Ticlopidine; D001241:Aspirin; C021137:alclometasone dipropionate; D008775:Methylprednisolone