title: Thrombolytic therapy in infants for femoral artery thrombosis following cardiac catheterisation.
abstract: Little information is available on the use of thromobolytic therapy in infants for femoral artery thrombosis after cardiac catheterisation. We report 12 cases (mean age: 4 months; range: 1-9 months) who received intravenous streptokinase (3000 U/kg bolus, 1000 U/kg/h) infusion. Five of them had undergone transarterial balloon dilatation procedures. Streptokinase was administered 48 h after catheterisation and continued for 4-20 h (mean 11.5 h). No detailed haematologic monitoring was done during therapy. Distal pulses were restored in all the patients. No complications were seen except a minor local ooze in two patients. We found that intravenous streptokinase is a safe and effective therapy for femoral artery thrombosis following cardiac catheterisation in infants.
authors: Department of Cardiology, All India Institute of Medical Sciences, New Delhi.
authors: S S
authors: SS
authors: Kothari
authors: R K
authors: RK
authors: Kumar
authors: S
authors: S
authors: Varma
authors: A
authors: A
authors: Saxena
mesh_terms: D006328:Cardiac Catheterization / Q000009:adverse effects*; D005263:Femoral Artery; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D013300:Streptokinase / Q000627:therapeutic use*; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase