Intravenous infusion of prostacyclin to prevent platelet thrombus during microvascular anastomoses.
Two cases are presented where the use of epoprostenol sodium (prostacyclin) was used intraoperatively to prevent platelet thrombus during arterial microvascular anastomoses. Both patients required a free muscle transfer at an unfavourable time following injury when platelet thrombus formation was a significant risk.
Gateley
D R
DR
Department of Plastic Surgery, Queen Mary's University Hospital, Roehampton, London, UK.
McAnulty
G R
GR
Martin
D L
DL
D000328:Adult; D000714:Anastomosis, Surgical; D001792:Blood Platelets / Q000502:physiology; D011464:Epoprostenol / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000601:surgery; D008866:Microsurgery; D009132:Muscles / Q000098:blood supply; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D013524:Surgical Flaps; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000517:prevention & control*
D010975:Platelet Aggregation Inhibitors; D011464:Epoprostenol