title: Hepatic failure associated with imipramine therapy.
abstract: Imipramine is an antidepressant drug that is rarely associated with mild liver function abnormalities. These are usually minor and transient liver enzyme elevations which return to normal levels upon discontinuation of the drug. We describe a 48-year-old male who developed subfulminant hepatic failure after imipramine usage, with complete recovery within three months after discontinuation of the drug.
authors: Liver unit, Hadassah University Hospital, Jerusalem, Israel.
authors: Y
authors: Y
authors: Ilan
authors: D
authors: D
authors: Samuel
authors: M
authors: M
authors: Reynes
authors: R
authors: R
authors: Tur-Kaspa
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007099:Imipramine / Q000009:adverse effects* / Q000627:therapeutic use; D017093:Liver Failure / Q000139:chemically induced* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
chemical_list: D000929:Antidepressive Agents, Tricyclic; D007099:Imipramine