title: [Two cases of Aspergillus endocarditis after cardiac surgery in childhood].
abstract: Aspergillus endocarditis has been considered as a fatal disease because of the difficulty of diagnosis and treatment. Two cases of Aspergillus endocarditis after congenital cardiac surgery are reported. One case was 5-year-old boy after patch closure of atrial septal defect and enlargement of porcine-pericardial patch to pulmonary arterial stenosis. Pulmonary arterial patch infection with vegetation occurred 13 months after operation, and he underwent pulmonary arterial reconstruction with E-PTFE patch after complete removal of porcine-pericardial patch. The other case was 5 year-old girl after repair of tetralogy of Fallot with autologus pericardial monocusp patch. Right ventricular outflow patch infection and mediastinitis occurred 14 months after operation. Although three times of the patch exchange, patch infection relapsed. Therefore, she underwent thorough curettage of infected tissue, and extra-anatomical bypass to bilateral pulmonary artery from right ventricle with E-PTFE Y-graft. The relapse of endocarditis has not been recognized after these surgical treatments in both patients.
authors: Department of Cardiovascular Surgery, Kita-Ishikai Hospital, Ohzu, Japan.
authors: S
authors: S
authors: Kawasaki
authors: Y
authors: Y
authors: Naitoh
authors: Y
authors: Y
authors: Takagaki
authors: Y
authors: Y
authors: Komai
authors: Y
authors: Y
authors: Noguchi
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis; D002675:Child, Preschool; D004696:Endocarditis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008297:Male; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012086:Reoperation
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole