[Influence of recirculation type blood cardioplegia on perfusion pressure in open heart surgery].
Infusion blood cardioplegia often decreases the perfusion pressure during open heart surgery. The blood level of bradykinin (BK) was measured in both the cardiopulmonary bypass (CPB) and blood cardioplegia circuit. Infusion cardioplegia with recirculation type circuit increased the BK level of cardioplegia and the perfusion pressure decreased abruptly with the increase BK level in the CPB circuit. In the case of single pass type circuit the BK level was not increased either in cardioplegia or CPB and perfusion pressure was not decreased. We concluded that the single pass type of cardioplegia circuit is superior to the recirculation type because of less production of BK.
Watanabe
T
T
Department of Thoracic Surgery, Nagoya University School of Medicine, Japan.
Murase
M
M
Yasuura
K
K
Matsuura
A
A
Maseki
T
T
Oohara
Y
Y
Ito
T
T
Sakai
Y
Y
Miyahara
K
K
Yuasa
T
T
Kawaratani
Y
Y
Yamada
T
T
D000368:Aged; D001794:Blood Pressure; D001920:Bradykinin / Q000097:blood; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D006324:Heart Arrest, Induced / Q000379:methods*; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010477:Perfusion
D001920:Bradykinin