title: A zinc-finger-type transcription factor WZF-1 that binds to a novel cis-acting element of histone gene promoters represses its own promoter.
abstract: WZF-1 is a zinc-finger protein which binds to the wheat histone gene promoter. Southwestern-binding analyses revealed that it bound a CACTC sequence, a novel positive cis-acting element. The activity of WZF-1 gene promoter, containing six CACTC sequences, was markedly reduced when WZF-1 was co-expressed, suggesting that WZF-1 is a transcriptional repressor.
authors: Department of Botany, Faculty of Science, Kyoto University, Japan.
authors: A
authors: A
authors: Sakamoto
authors: S
authors: S
authors: Omirulleh
authors: T
authors: T
authors: Nakayama
authors: M
authors: M
authors: Iwabuchi
mesh_terms: D001483:Base Sequence; D001665:Binding Sites / Q000235:genetics; D018744:DNA, Plant / Q000235:genetics / Q000378:metabolism; D017343:Genes, Plant; D006657:Histones / Q000235:genetics*; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014908:Triticum / Q000235:genetics / Q000378:metabolism; D016335:Zinc Fingers / Q000235:genetics
chemical_list: D018744:DNA, Plant; D006657:Histones; D011993:Recombinant Fusion Proteins; D014157:Transcription Factors