[The neuronal reaction of the rat neocortex to damage to the central serotoninergic system].
Pyramidal neurons of the motor cortex II-III layers developed degenerative alterations in response to a selective damage of the rat brain serotoninergic system, whereas those of the V-VI layers manifested adaptive changes. The finding could be due to a selective sensitivity of the target cells in respect to serotonin deficiency.
Otellin
V A
VA
Korzhevskiĭ
D E
DE
Val'kovich
E I
EI
Malakhova
O E
OE
D015116:5,7-Dihydroxytryptamine / Q000494:pharmacology; D018759:Adrenergic Uptake Inhibitors / Q000494:pharmacology; D000818:Animals; D003891:Desipramine / Q000494:pharmacology; D008297:Male; D009044:Motor Cortex / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D017966:Pyramidal Cells / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D011985:Receptors, Serotonin / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D017366:Serotonin Receptor Agonists / Q000494:pharmacology; D018709:Statistics, Nonparametric; D013997:Time Factors
D018759:Adrenergic Uptake Inhibitors; D011985:Receptors, Serotonin; D017366:Serotonin Receptor Agonists; D015116:5,7-Dihydroxytryptamine; D003891:Desipramine
Reaktsiia neĭronov neokorteksa krys na povrezhdenie tsentral'noĭ serotoninergicheskoĭ sistemy.