Erythrokeratodermia variabilis present at birth: case report and review of the literature.
A healthy boy had the distinctive lesions of erythrokeratodermia variabilis (EKV) at birth. Twenty-eight patients described in the literature had EKV that presented in childhood. Nine of the 28 were said to have had a rash since birth, but none were distinctive of EKV. To our knowledge this is the first well-documented case describing a child born with the skin manifestations of EKV. We conclude that patients with EKV are infrequently born with a rash, and that only very rarely when the rash is present is it suggestive of the disorder.
Hendrix
J D
JD
Department of Dermatology, University of Virginia School of Medicine, Charlottesville 22908, USA.
Greer
K E
KE
D003873:Dermatitis, Exfoliative / Q000151:congenital* / Q000235:genetics / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D012867:Skin / Q000473:pathology