[Formation of so-called byproducts (propanols, butanols et al.) from ethanol by microorganisms].
Microbiological literature implies and furnishes evidence that aliphatic alcohols and the corresponding carboxylates as well as acetone can be produced from ethanol during microbial metabolic processes. Propionate/propanol-1 followed by butyrate can be obtained by means of step-by-step reductive carboxylation of acetyl-CoA. Both butyrate/butanol-1 and caproate/hexanol-1 are typical fermentation products of Clostridium kluyvery. In cases where butyrate decomposition is disrupted up to 50% of butyrate is isomerised to isobutyrate. In addition to ethanol, butyrate and butanol-1, isopropanol and acetone are characteristic products of commercially used Clostridia. One would expect that saccharolytic organisms producing ethanol in addition to other "solvents" (butanol-1, acetone, isopropanol) can also synthesise the solvents if the substrate is changed (ethanol instead of carbohydrate). Under carbon monoxide, formiate and hydrogen, some CODH-active Clostridia can, very efficiently, convert various carboxylates into the corresponding alcohols. There are several groups of organisms present in human intestinal tract that can utilise ethanol and other alcohols.
Stöhlmacher
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Institut für Rechtsmedizin Medizinischen Fakultät Universität Rostock
D000433:1-Propanol / Q000493:pharmacokinetics*; D000437:Alcoholism / Q000097:blood*; D000438:Alcohols / Q000493:pharmacokinetics*; D000818:Animals; D001419:Bacteria / Q000378:metabolism*; D001711:Biotransformation; D000440:Butanols / Q000493:pharmacokinetics*; D003013:Clostridium / Q000378:metabolism; D000431:Ethanol / Q000493:pharmacokinetics*; D005285:Fermentation; D006801:Humans; D007422:Intestines / Q000382:microbiology*
D000438:Alcohols; D000440:Butanols; D000431:Ethanol; D000433:1-Propanol
Zur Bildung sogenannter Begleitstoffe (Propanole, Butanole u. a.) aus Ethanol durch Mikroorganismen.