title: [A successful treatment with a continuous intravenous lidocaine for a cluster of minor seizures in a patient with Doose syndrome].
abstract: We reported a 7-year-old girl with myoclonic-astatic epilepsy of early childhood (Doose syndrome). She had minor seizures (i. e. absence, atonic and myoclonic seizures) refractory to treatment with many kinds of anti-epileptic drugs as well as thyrotropin releasing hormone. Though she had suffered from long-lasting clusters of minor seizures, the treatment with continuous intravenous lidocaine successfully brought a case of prolonged remission of both clinical seizures and EEG abnormalities. It has been reported that lidocaine is effective mainly for partial seizures. The efficacy of lidocaine for generalize seizures, however, has been reported only in a few papers. We considered that the treatment with continuous intravenous lidocaine is indicated in patients with Doose syndrome presenting with a cluster of refractory minor seizures.
authors: Department of Pediatrics, Yamanashi Medical University.
authors: H
authors: H
authors: Kanemura
authors: M
authors: M
authors: Aihara
authors: Y
authors: Y
authors: Sata
authors: K
authors: K
authors: Hatakeyama
authors: Y
authors: Y
authors: Hinohara
authors: Y
authors: Y
authors: Kamiya
authors: C
authors: C
authors: Shimoda
authors: S
authors: S
authors: Nakazawa
mesh_terms: D002648:Child; D004831:Epilepsies, Myoclonic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008012:Lidocaine / Q000008:administration & dosage*
chemical_list: D008012:Lidocaine