ACEA-1011, a novel NMDA receptor/glycine site antagonist, produces antinociception but not tolerance in the formalin test in mice.
Lutfy
K
K
Department of Pharmacology, University of California, Irvine 92717, USA.
Keana
J F
JF
Weber
E
E
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004361:Drug Tolerance; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology*; D005557:Formaldehyde; D008297:Male; D051379:Mice; D010147:Pain Measurement / Q000187:drug effects*; D011810:Quinoxalines / Q000494:pharmacology*; D018009:Receptors, Glycine / Q000037:antagonists & inhibitors*; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors*
D000700:Analgesics; D018690:Excitatory Amino Acid Agonists; D011810:Quinoxalines; D018009:Receptors, Glycine; D016194:Receptors, N-Methyl-D-Aspartate; C082999:ACEA 1011; D005557:Formaldehyde