[Nuclear ploidy in atrial cardiomyocytes in patients with heart disease].
The content of DNA and proteins has been studied morphometrically in intraoperative biopsies of patients of different ages with congenital heart diseases and rheumatic mitral stenosis. Hemodynamic hyperfunction provoked premature polyploidy of cardiomyocytes nuclei in children with congenital vitium cordis. In cardiomyocytes of 20-50-year-old patients with acquired vitium cordis polyploidy with an increasing age does not occur, but a decline in protein synthesis and intracellular edema are observed.
Ibragimova
I F
IF
Medical Institute, Ufa.
Danilov
R K
RK
Zagidullin
Sh Z
ShZ
D017677:Age Distribution; D006332:Cardiomegaly / Q000473:pathology; D002467:Cell Nucleus / Q000235:genetics*; D003593:Cytoplasm / Q000737:chemistry; D004247:DNA / Q000032:analysis; D006325:Heart Atria / Q000473:pathology*; D006330:Heart Defects, Congenital / Q000473:pathology*; D008946:Mitral Valve Stenosis / Q000473:pathology; D011003:Ploidies; D011506:Proteins / Q000032:analysis
D011506:Proteins; D004247:DNA
Ploidnost' iader predserdnykh kardiomiotsitov u bol'nykh s porokami serdtsa.