title: Spinal cord stimulation versus spinal infusion for low back and leg pain.
abstract: The relative roles of spinal cord stimulation and the spinal infusion of opioids in the treatment of chronic, non-cancer lower body pain remains unclear. This report contains a retrospective analysis of patients with chronic lower body, neuropathic pain and treated over a 5 year period. Unilateral leg and/or buttock pain was treated initially with spinal stimulation and bilateral leg or mainly low back pain was treated initially with spinal infusions. 26 patients received spinal stimulation. Pain relief was > or = 50% in 16 (62%) with increased activity levels. Stimulator coverage was most difficult or failed in patients with buttock pain. 16 patients received long-term spinal infusions. Pain relief was > or = 50% in 2 (13%) but 25-49% in another 8 (50%) with stable infusion doses and was best in patients requiring low-dose (< 1 mg/h morphine intrathecal) infusions in the trial period. The review indicates that spinal infusions may be best for bilateral or axial pain that has not responded to spinal stimulation. Clonidine appears to be an alternative in high-dose morphine patients. New diamond-shaped electrode and dual quadripolar arrays appear to be very helpful for back, buttock, and/or bilateral leg pain patterns.
authors: Department of Neurosurgery, M.D. Anderson Cancer Center Houston, Texas, USA.
authors: S J
authors: SJ
authors: Hassenbusch
authors: M
authors: M
authors: Stanton-Hicks
authors: E C
authors: EC
authors: Covington
mesh_terms: D000328:Adult; D000368:Aged; D015360:Analgesia, Epidural / Q000295:instrumentation; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004567:Electrodes, Implanted; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D015918:Infusion Pumps, Implantable; D017116:Low Back Pain / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D010147:Pain Measurement; D010166:Palliative Care; D012585:Sciatica / Q000503:physiopathology / Q000628:therapy*; D013116:Spinal Cord / Q000503:physiopathology*; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine