[Features of vitamin D3 metabolism in liver cells in experimental diabetes mellitus].
The uptake of vitamin D3 by the liver cells and its hydroxylation in the hepatocytes of rats at experimental diabetes has been studied. It is proved that in this pathology the disturbances of vitamin D3 exchange in the rat liver take place. It is concluded that the lowering of the level of absorption of vitamin D3 by hepatocytes and its transportation to these cells from reticulocytes as well as the inhibition of vitamin D3-25-hydroxylase liver systems can be the most probable cause of these disturbances.
Stefanov
M V
MV
Apukhovskaia
L I
LI
D000042:Absorption; D000818:Animals; D001692:Biological Transport; D002762:Cholecalciferol / Q000378:metabolism*; D053493:Cholestanetriol 26-Monooxygenase; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006900:Hydroxylation; D008099:Liver / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D012156:Reticulocytes / Q000378:metabolism; D013250:Steroid Hydroxylases / Q000037:antagonists & inhibitors
D002762:Cholecalciferol; D013250:Steroid Hydroxylases; D053493:Cholestanetriol 26-Monooxygenase
Osobennosti obmena vitamina D3 v kletkakh pecheni pri éksperimental'nom sakharnom diabete.