Leucocyte and thrombocyte responses in dogs experimentally infected with Trypanosoma brucei.
Three dogs were subcutaneously infected with Trypanosoma brucei strain ILRAD 1797. Artificial haemolytic anaemia was induced in 2 other dogs by phlebotomy, heat treatment and re-infusion of the blood, while 2 dogs were kept as control animals. The infected animals developed pan-leucopenia and thrombocytopenia, while the dogs with artificial haemolytic anaemia developed leucocytosis and thrombocytosis. These findings suggest that there was a bone marrow depressing factor in the plasma of T. brucei-infected dogs especially as it affected leucocyte production.
Omotainse
S O
SO
Department of Veterinary Pathology, University of Ibadan, Nigeria.
Anosa
V O
VO
D000818:Animals; D004283:Dog Diseases / Q000097:blood / Q000469:parasitology*; D004285:Dogs; D007958:Leukocyte Count; D009549:Nigeria; D010976:Platelet Count; D014346:Trypanosoma brucei brucei; D014353:Trypanosomiasis, African / Q000097:blood / Q000662:veterinary*