title: Stomal malignant transformation of respiratory papilloma, with neck metastasis: case report.
abstract: A case of spontaneous malignant transformation at the mucocutaneous junction of the tracheostomy site in a child with recurrent respiratory papilloma is presented. A paratracheal neck metastasis also developed in the same patient in early adulthood. The respiratory papillomata were first noted at the age of 1.5 years, stomal malignancy at age of seven while the neck mass at age 14 years. During the prolong course of 13.5 years, the papillomas were growing aggressively, mainly in the trachea and main bronchi. Repeated excisions, radiotherapy and a variety of drugs were tried and discussed. The importance of close observation and follow-up is stressed. Currently at the age of 16 years, the patient is alive and well and leading normal activities.
authors: Children's National Medical Centre, Washington DC, USA.
authors: K
authors: K
authors: Shamboul
mesh_terms: D000293:Adolescent; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008297:Male; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D010212:Papilloma / Q000473:pathology*; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D014139:Tracheostomy / Q000009:adverse effects*