title: 3-D TOP-A software package for the topological analysis of image sequences.
abstract: The software package 3-D TOP is a measurement software which has been developed to meet the needs of those who analyze mechanical serial sections in histology and optical sections in laser scanning microscopy. The semiautomatic definition of topological centerlines is the backbone of this software. The three basic advantages in using the concept of topology are (a) resolving ambiguities for surface rendering, (b) flexible definition of objects for automatic identification, labeling, and measurement, and (c) topological quantification of complex forms. A specific application of this software to lung research is demonstrated.
authors: Image Processing Laboratory, Institute of Anatomy and Cell Biology, University Clinic Giessen, Germany.
authors: A
authors: A
authors: Kriete
authors: T
authors: T
authors: Schwebel
mesh_terms: D000818:Animals; D003196:Computer Graphics; D003198:Computer Simulation; D008168:Lung / Q000166:cytology / Q000648:ultrastructure*; D018613:Microscopy, Confocal; D008961:Models, Structural; D051381:Rats; D012984:Software