[Conventional nuclear medical diagnosis in the after care of heart transplantation].
Actually more than 80% of heart recipients survive the first postoperative year. Early death is mainly caused by rejection and acute infection. After the first year progressive graft atherosclerosis has the greatest impact on prognosis. The review presents scintigraphic methods that have reached clinical impact in the diagnosis of rejection and vascular complications. Immunoscintigraphy with 111In-labelled monoclonal antibodies against myosin proved to be of importance in the diagnosis of rejection especially in long-term follow-up. Perfusion scintigraphy reveals vital and ischemic myocardium. In heart transplant recipients radionuclide ventriculography has been widely replaced by echocardiography. Up to now, the evaluation of increasing nerval integration with 123I-MIBG has not reached clinical impact.
Puskás
C
C
Klink und Poliklinik für Nuklearmedizin, Westfälische Wilhelms-Universi
Kerber
S
S
Weyand
M
M
Schober
O
O
D000206:Actuarial Analysis; D000911:Antibodies, Monoclonal; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000000981:diagnostic imaging*; D006321:Heart / Q000000981:diagnostic imaging*; D016027:Heart Transplantation / Q000401:mortality; D006801:Humans; D007205:Indium Radioisotopes; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D016719:Radioimmunodetection; D015996:Survival Rate
D000911:Antibodies, Monoclonal; D007205:Indium Radioisotopes
Konventionelle nuklearmedizinische Diagnostik in der Nachsorge nach Herztransplantation.