title: Neuroimaging criteria for vascular dementia.
abstract: OBJECTIVE
  To examine published imaging criteria that separate cranial computed tomographic (CT) scans into grades of increasing support for a diagnosis of vascular dementia (VaD).
  
  
  METHODS
  Patients were divided into 4 grades of increasing extent of vascular lesions on CT. The frequency of VaD was compared between these grades.
  
  
  METHODS
  A university department of neurology.
  
  
  METHODS
  Forty-two consecutive patients who underwent neuropsychological assessment for possible dementia and who had a CT scan performed within 6 months following any stroke causing dementia. Patients with delirium, severe aphasia, and motor and/or sensory deficits that impaired neuropsychological testing and patients with mass lesions or nonvascular white matter disease shown on CT were excluded.
  
  
  METHODS
  The National Institute of Neurological Disorders and Stroke and the Association Internationale pour la Recherche et l'Enseignement en Neurosciences criteria for probable VaD.
  
  
  RESULTS
  The frequency of VaD was greater in patients with grade 1 (7 [50%] of 14, P = .01), grade 2 (2[50%] of 4, P = .2), and grade 3(7[78%] of 9, P = .002) scans than the frequency of VaD with grade O scans (1[7%] of 15). There was a linear association of the frequencies of VaD between imaging grades (P = .0008). In a subgroup of patients with neuropsychological deficits caused by cerebrovascular disease, there was a linear association of the severity of the deficits between imaging grades (P = .007).
  
  
  CONCLUSIONS
  We conclude that our criteria can separate CTs into increasing levels of support for a diagnosis of VaD. The extent of vascular lesions on CT reflects the severity of associated neuropsychological deficts.
authors: Department of Neurology, State University of New York at Buffalo, Buffalo General Hospital, USA.
authors: P
authors: P
authors: Pullicino
authors: R H
authors: RH
authors: Benedict
authors: D X
authors: DX
authors: Capruso
authors: N
authors: N
authors: Vella
authors: S
authors: S
authors: Withiam-Leitch
authors: P L
authors: PL
authors: Kwen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015140:Dementia, Vascular / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed