title: Intravenous infusion of prostacyclin to prevent platelet thrombus during microvascular anastomoses.
abstract: Two cases are presented where the use of epoprostenol sodium (prostacyclin) was used intraoperatively to prevent platelet thrombus during arterial microvascular anastomoses. Both patients required a free muscle transfer at an unfavourable time following injury when platelet thrombus formation was a significant risk.
authors: Department of Plastic Surgery, Queen Mary's University Hospital, Roehampton, London, UK.
authors: D R
authors: DR
authors: Gateley
authors: G R
authors: GR
authors: McAnulty
authors: D L
authors: DL
authors: Martin
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical; D001792:Blood Platelets / Q000502:physiology; D011464:Epoprostenol / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000601:surgery; D008866:Microsurgery; D009132:Muscles / Q000098:blood supply; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D013524:Surgical Flaps; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000517:prevention & control*
chemical_list: D010975:Platelet Aggregation Inhibitors; D011464:Epoprostenol