[Joint and systemic manifestations related to type 2 anti-mitochondrial antibodies].
The aim of the study was to assess the significance of type 2 anti-mitochondrial antibodies in patients with systemic and inflammatory rheumatic disease. Articular and systemic manifestations of 8 patients associated with type 2 anti-mitochondrial antibodies are described. All the patients had hepatic abnormalities, and 5 of them disclosed a primary biliary cirrhosis. Articular and systemic manifestations were similar to those observed in primary biliary cirrhosis. Therefore, the finding of anti-mitochondrial antibodies in patients with systemic or inflammatory rheumatic disease implies research for other systemic manifestations such as primary biliary cirrhosis.
Dhôte
R
R
Service de Médecine Interne, Hôpital Cochin, Paris.
Christoforov
B
B
Weill
B
B
Menkes
C J
CJ
D000368:Aged; D000369:Aged, 80 and over; D000906:Antibodies / Q000032:analysis* / Q000502:physiology; D001168:Arthritis / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000276:immunology; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000276:immunology; D008105:Liver Cirrhosis, Biliary / Q000276:immunology; D008875:Middle Aged; D008928:Mitochondria / Q000276:immunology* / Q000648:ultrastructure; D012189:Retrospective Studies
D000906:Antibodies
Manifestations articulaires et systémiques associées aux anticorps anti-mitochondries de type 2.