title: Biomechanics of fusion and stabilization.
abstract: METHODS
  Literature review.
  
  
  OBJECTIVE
  To assess the state of the art in the biomechanics of fusions, fusion materials, and the use of instrumentation by critically reviewing the literature as modified by group discussion.
  
  
  BACKGROUND
  A considerable body of knowledge addresses these issues based on in vitro biomechanical testing and mathematical models. Much biomechanical information is available regarding the biomechanical behavior of the graft material, the fusion, and the instrumentation. Biomechanical testing and finite element analyses remain to be done on semirigid devices, interbody spacers, and artificial discs.
  
  
  METHODS
  The literature was reviewed to analyze papers written on the following topics: graft material, in vitro tests of instrumentation, device evaluation using artificial spine models, in vivo human studies, animal models, finite element studies, effects of rigidity, and bone adaptive remodeling.
  
  
  RESULTS
  One hundred forty-one modern articles were reviewed and their data analyzed. Much important insight has come from biomechanical studies.
  
  
  CONCLUSIONS
  Fusions are largely successful. Biomechanical data is complete except for some of the latest devices.
authors: Department of Biomedical Engineering, University of Iowa, Iowa City, USA.
authors: V K
authors: VK
authors: Goel
authors: M H
authors: MH
authors: Pope
mesh_terms: D001696:Biomechanical Phenomena; D006801:Humans; D013123:Spinal Fusion / Q000379:methods*; D013131:Spine / Q000502:physiology*