title: [Perforating verruciform collagenoma, an exogenous inclusion skin disease? Apropos of a case induced by calcium chloride].
abstract: BACKGROUND
  Perforating verruciform collagenoma, first described in 1963, designates papular and keratotic post-trauma lesions which show an aspect of epidermal perforation microscopically with large fragments of collagen issuing through fistulous chimneys, more or less pycnotic polynuclears and squamating or necrotic epidermal cells. Three publications have presented this diagnosis.
  
  
  METHODS
  We observed a patient with multiple lesions with macroscopic and microscopic presentations suggestive of perforating verruciform collagenoma. The lesions appeared after scratches and inoculation with calcium chloride.
  
  
  CONCLUSIONS
  This case is similar to those observed after intradermal inoculation of calcium salts. In the 4 previous cases, perforating verruciform collagenoma was associated with trauma allowing the intradermal penetration of a particular foreign material (glass wool, vegetable debris, drugs or intravenous injections, wound caused by a metallic garbage bin). The exceptional nature of perforating verruciform collagenoma in highly frequent skin wounds would suggest that a very particular post-trauma process is occurring caused by the introduction of an exogenous substance within the derma: calcium chloride in our case, a non-specific material in the four previous cases.
authors: Service de Dermatologie, Hôpital de l'Antiquaille, Lyon.
authors: G
authors: G
authors: Moulin
authors: B
authors: B
authors: Balme
authors: M
authors: M
authors: Musso
authors: L
authors: L
authors: Thomas
mesh_terms: D000328:Adult; D002122:Calcium Chloride / Q000009:adverse effects*; D003095:Collagen Diseases / Q000139:chemically induced* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007642:Keratosis / Q000139:chemically induced / Q000473:pathology; D007868:Leg Dermatoses / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology
chemical_list: D002122:Calcium Chloride
vernacular_title: Le collagénome perforant verruciforme, une dermatose par inclusion exogène? A propos d'un cas induit par le chlorure de calcium.