Ophthalmological and neuro-ophthalmological involvement in Churg-Strauss syndrome: a case report.
BACKGROUND
It is well known that different types of eye involvement may develop during the course of systemic vasculitides.


METHODS
We report here a case of Churg-Strauss syndrome (allergic granulomatous angiitis) characterized by the presence of multiple ophthalmological and neuro-ophthalmological lesions, i.e., mononeuritis of the fourth cranial nerve, multifocal choroidal ischaemia, and bilateral ischaemic optic neuropathy.


RESULTS
Ischaemic lesions in the posterior ciliary plexus and chorio-retinal circulation, which appeared simultaneously after a phase of disease activity, were documented.


CONCLUSIONS
The simultaneous occurrence of multiple ocular features in a patient with Churg-Strauss syndrome suggests that regional vasculitis may be the pathological mechanism underlying the multiple ophthalmological lesions in this disorder.
Vitali
C
C
Rheumatology Unit, University of Pisa, Italy.
Genovesi-Ebert
F
F
Romani
A
A
Jeracitano
G
G
Nardi
M
M
D002829:Choroid / Q000098:blood supply; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000473:pathology; D003389:Cranial Nerve Diseases / Q000150:complications / Q000473:pathology; D005128:Eye Diseases / Q000150:complications* / Q000473:pathology; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000473:pathology; D008875:Middle Aged; D009422:Nervous System Diseases / Q000150:complications* / Q000473:pathology; D009443:Neuritis / Q000150:complications / Q000473:pathology; D018917:Optic Neuropathy, Ischemic / Q000150:complications / Q000473:pathology; D014321:Trochlear Nerve / Q000473:pathology