Discrepancies between results by E-test and standard microbroth dilution testing of Streptococcus pneumoniae for susceptibility to vancomycin.
Vancomycin susceptibility testing of Streptococcus pneumoniae by the E-test consistently resulted in MICs that were at the upper limit of the 1-microgram/ml susceptible category defined by current National Committee for Clinical Laboratory Standards guidelines and were always higher than MICs obtained by microbroth dilution. Three of five E-test results for S. pneumoniae ATCC 49619 were higher than the acceptable limits.
Hashemi
F B
FB
Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, USA.
Schutze
G E
GE
Mason
E O
EO
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D004352:Drug Resistance, Microbial; D005069:Evaluation Studies as Topic; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods* / Q000592:standards; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000382:microbiology; D012015:Reference Standards; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D014640:Vancomycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D014640:Vancomycin