title: [Study of neonatal immunological function in breast feeding and formula feeding].
abstract: OBJECTIVE
  To determine 4 immunoglobulins and soluble interleukin-2 receptor (sIL-2R) in maternal and neonatal serum, in order to study the immunological functions in the neonates.
  
  
  METHODS
  80 cases were divided into three groups: (1) breast feeding group (30 cases), (2) formula feeding group (20 cases), and (3) mixed feeding group (30 cases). Maternal serum was collected prior to delivery and on the sixth day after delivery. Neonatal serum was collected on the third and sixth day after delivery. Umbilical blood at birth was obtained also. Secretory immunoglobulin A (SIgA), IgA, IgG, IgM and sIL-2R levels in the sera were determined by radioimmunoassay and enzyme-linked immunosorbent assay.
  
  
  RESULTS
  The SIgA, IgA, IgG, IgM and sIL-2R levels in maternal serum were not significantly different among 3 groups, while neonatal serum SIgA, IgA, IgG, IgM and sIL-2R levels on the sixth day after delivery in the breast feeding group were significantly higher than those in the formula breeding group (P < 0.001, P < 0.001, P < 0.05, P < 0.05).
  
  
  CONCLUSIONS
  Breast feeding may improve neonatal humoral and cellular immunity.
authors: Changchun Hospital of Obstetrics and Gynecology.
authors: Y
authors: Y
authors: Zheng
authors: W
authors: W
authors: Shang
authors: Y
authors: Y
authors: Wang
mesh_terms: D001903:Bottle Feeding; D001942:Breast Feeding; D005260:Female; D006801:Humans; D007121:Immunocompetence; D007071:Immunoglobulin A, Secretory / Q000097:blood; D007136:Immunoglobulins / Q000097:blood; D007225:Infant Food; D007231:Infant, Newborn; D015375:Receptors, Interleukin-2 / Q000378:metabolism
chemical_list: D007071:Immunoglobulin A, Secretory; D007136:Immunoglobulins; D015375:Receptors, Interleukin-2