Bilateral acoustic neurofibromatosis with bilateral multicentric facial schwannomas.
A case report of a 20-year-old female with bilateral acoustic neurofibromatosis (NF-2) and bilateral facial schwannomas is presented. Multiple segmental schwannomas were found with clinically intact tissue between each tumoral enlargement in the right parotid region. Translocation (2;8) (p2.4:q2.1) was detected in this patient, and has not been reported in a schwannoma until now. The patient's family would not allow any major surgery to be performed.
Kiroğlu
M M
MM
Department of Otolaryngology, Faculty of Medicine, University of Cukurova, Balcali/Adana, Turkey.
Zorludemir
S
S
Süleymanova
D
D
D000328:Adult; D001706:Biopsy; D002889:Chromosomes, Human, Pair 2; D002898:Chromosomes, Human, Pair 8; D003390:Cranial Nerve Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D005154:Facial Nerve / Q000473:pathology; D005155:Facial Nerve Diseases / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007621:Karyotyping; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D016518:Neurofibromatosis 2 / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic / Q000235:genetics