[Effects of selenium and germanium on lipid peroxidation in rats fed with low-selenium grain].
Rats were fed with grain produced in the area prevalent of Keshan disease for 12 weeks, by adding certain amount of sodium selenite (Na2SeO3) and carboxylethylgermanium (Ge-132) to study the combined effects of selenium and germanium on lipid peroxidation and metabolism of free radicals in their bodies. Results showed selenium and germanium added to the grain could reduce the content of free radicals in rats' liver and kidney tissues, and that of lipid peroxide in their heart, liver and kidney, and increase the activities of glutathione peroxidase (GSH-Px) in their blood, in a synergic way.
Xie
W
W
Department of Environmental Health Tongji Medical University, Wuhan.
Chen
X
X
Yang
K
K
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D005260:Female; D005857:Germanium / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D009942:Organometallic Compounds / Q000494:pharmacology*; D011422:Propionates; D051381:Rats; D017208:Rats, Wistar; D018038:Sodium Selenite / Q000494:pharmacology*
D000975:Antioxidants; D009942:Organometallic Compounds; D011422:Propionates; D005857:Germanium; C066750:propagermanium; D018038:Sodium Selenite