Sensitivity of Australian isolates of Salmonella enteritidis to nitrofurantoin and furazolidone.
Susceptibility of 66 and 62 Australian isolates of Salmonella enteritidis to nitrofurantoin and furazolidone, respectively, was determined. Most isolates were susceptible to both antibiotics. Cross-resistance was low among all isolates, but higher among the subset of phage type 4 isolates. These results contrast directly with those of a previous study (Rampling, A., Upson, R. and Brown, D.F.J. (1990) J. Antimicrob. Chemother., 25: 285-290). Sensitivity among Australian isolates of S. enteritidis does to some extent, support the contention that furans may have played a role in the selection and enhanced colonisation of poultry by Salmonella enteritidis in Britain. Furthermore, nitrofurantoin should not be used as a selective agent in the isolation of Salmonella enteritidis.
Cox
J M
JM
Department of Microbiology, University of Queensland, Brishane, Australia. julian.cox@unsw.edu.au
Brook
M D
MD
Woolcock
J B
JB
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001315:Australia; D005664:Furazolidone / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009582:Nitrofurantoin / Q000494:pharmacology*; D012477:Salmonella enteritidis / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D005664:Furazolidone; D009582:Nitrofurantoin