Magnetic resonance imaging of the normal mouse brain: comparison with histologic sections.
Details in the living animal can be compared with respective histologic section taken after death. In less than 35 min, 12 to 16 coronal and transverse images through the brain can be obtained, each with an in-plane resolution of 100 x 200 microns and a slice thickness of 900 microns. The experimental parameters can be manipulated not only to achieve different tissue contrast but also to access any desired plane.
Munasinghe
J P
JP
Herchel Smith Laboratory for Medicinal Chemistry, Cambridge University School of Clinical Medicine, England.
Gresham
G A
GA
Carpenter
T A
TA
Hall
L D
LD
D000818:Animals; D001921:Brain / Q000166:cytology*; D002531:Cerebellum / Q000166:cytology; D006652:Histological Techniques; D008279:Magnetic Resonance Imaging; D051379:Mice; D009833:Olfactory Pathways / Q000166:cytology; D016548:Prosencephalon / Q000166:cytology; D012016:Reference Values