title: The physiology of boredom, depression and senile dementia.
abstract: Mental stimulation ensures the flow of blood, oxygen and nutrients to the brain. The stimulation can be either generated internally from thought and rumination or externally from our environment via the senses. Without this stimulation, neuron shrinkage and atrophy eventually may lead to depression and senile dementia. This paper explains why mental stimulation may be prevented from realizing its beneficial effects of increasing the blood flow to the brain. The hypothesis is based on feedback biological mechanisms that prevent overload of the neural circuitry due to excessive mental stimulation. However, if overstimulation is maintained over a long period and, with it, the overload protection process, it may eventually lead to permanent depletion of neuron connections and also neural communications.
authors: Green Gables, South Humberside, UK.
authors: M N
authors: MN
authors: Saunders
mesh_terms: D001887:Boredom; D001921:Brain / Q000502:physiology* / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D003704:Dementia / Q000503:physiopathology*; D003863:Depression / Q000503:physiopathology*; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008959:Models, Neurological; D008960:Models, Psychological; D009474:Neurons / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology; D012677:Sensation / Q000502:physiology*; D013850:Thinking
chemical_list: D018377:Neurotransmitter Agents; D005947:Glucose