Laboratory detection of antiphospholipid antibodies.
'Antiphospholipid' (aPL) antibodies are a heterogenous group of autoantibodies that are now considered to be directed mainly to plasma proteins or protein-phospholipid complexes. Standardisation of assays for anticardiolipin (aCL) antibodies and lupus anticoagulants (LA) have been fraught with difficulty despite numerous attempts to perform this by International Standardisation Workshops and Committees.
Kandiah
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DA
Department of Immunology, Allergy and Infectious Disease, University of New South Wales, St George Hospital, Kogarah, Australia.
Krilis
S A
SA
D000818:Animals; D017153:Antibodies, Anticardiolipin / Q000032:analysis / Q000097:blood; D017152:Antibodies, Antiphospholipid / Q000032:analysis / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001780:Blood Coagulation Tests; D001798:Blood Proteins / Q000276:immunology; D002417:Cattle; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods / Q000592:standards; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000032:analysis / Q000097:blood; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D010314:Partial Thromboplastin Time; D010743:Phospholipids / Q000276:immunology; D011485:Protein Binding
D017153:Antibodies, Anticardiolipin; D017152:Antibodies, Antiphospholipid; D015415:Biomarkers; D001798:Blood Proteins; D016682:Lupus Coagulation Inhibitor; D010743:Phospholipids