Vasculitis post-autologous transplant causing pulmonary shadows in a patient with Hodgkin's disease.
A 29-year-old male was treated for recurrent Hodgkin's disease with autologous bone marrow and peripheral blood stem cell transplantation. CT scanning shortly after transplantation showed widespread infiltrates, which appeared to be malignant at thorocoscopy but which biopsy showed to be vasculitis. A prolonged reducing dose of steroids has successfully controlled the vasculitis and his current CT scan of lung has no shadows. The cause of his vasculitis is unclear and the case illustrates the importance of tissue diagnosis in possible relapses of Hodgkin's disease following high-dose chemotherapy.
McCloy
M
M
Haematology Department, Belfast City Hospital, Northern Ireland.
Morris
T C
TC
McGuigan
J A
JA
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D008297:Male; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous; D014657:Vasculitis / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000209:etiology*