title: Motor nerve sprouting induction by a nerve explant in normal and vitamin E-deficient rats.
abstract: Sprouting induction by a peripheral degenerating nerve has been evaluated in normal and vitamin E-deficient rats. A piece of sural nerve was grafted close to the peroneal nerve of the same animal: at one and two months after grafting thin unmyelinated axons were visible in the graft and they were sometimes functionally active; when nerve explant was frozen before grafting, sprouting induction did not take place either in controls or in vitamin E-deficient animals. No difference was noted in sprouting induction between the two groups, while degeneration showed a different time course. Some hypotheses of possible stimuli of sprouting induction are discussed.
authors: Istituto di Anatomia e Fisiologia, University of Urbino, Italy.
authors: C
authors: C
authors: Cuppini
authors: P
authors: P
authors: Ambrogini
authors: O
authors: O
authors: Buffi
authors: R
authors: R
authors: Cuppini
authors: S
authors: S
authors: Ciaroni
authors: T
authors: T
authors: Cecchini
mesh_terms: D000818:Animals; D005615:Freezing; D008297:Male; D008854:Microscopy, Electron; D018482:Muscle, Skeletal / Q000502:physiology; D009410:Nerve Degeneration / Q000502:physiology*; D009414:Nerve Growth Factors / Q000502:physiology*; D009416:Nerve Regeneration / Q000502:physiology*; D010525:Peripheral Nerves / Q000502:physiology*; D010543:Peroneal Nerve / Q000601:surgery; D051381:Rats; D017207:Rats, Sprague-Dawley; D012583:Schwann Cells / Q000648:ultrastructure; D013497:Sural Nerve / Q000473:pathology / Q000637:transplantation; D014811:Vitamin E Deficiency / Q000503:physiopathology*
chemical_list: D009414:Nerve Growth Factors