[Progressive supranuclear palsy].
Progressive supranuclear palsy (PSP) was a distinct clinicopathological syndrome described by Steele, Richardson and Olszewski in 1964. In 1974, Narabayashi and the present author described a syndrome of levodopa unresponsive pure akinesia or freezing without rigidity or tremor affecting gait, hand writing and speech. In a series of subsequent reports in Japan, evidence has indicated that pure akinesia often represents a pre-oculomotor form of PSP. In this sense, the syndrome of pure akinesia/PSP is proposed. The pathogenesis and etiology of PSP and related conditions remain to be cleared.
Imai
H
H
Department of Neurology, Juntendo University School of Medicine.
D003937:Diagnosis, Differential; D005133:Eye Movements; D005260:Female; D005684:Gait; D006801:Humans; D008875:Middle Aged; D013060:Speech; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis / Q000503:physiopathology; D014956:Writing