[Evaluation of the usefulness of bronchoalveolar lavage for prognosing and monitoring the treatment of patients with chronic allergic alveolitis].
In 29 patients with chronic allergic alveolitis broncho-alveolar lavage BAL and lung function tests were performed before and after one year of Prednisone treatment. We observed significantly (p < 0.001) decrease of BAL lymphocytes from 52% to 32% and significantly (p < 0.001) increase of BAL macrophages from 33% to 54%. We found negative correlation between percentage of BAL neutrophils before treatment and annual changes of DLCO (r = 0.37 p < 0.05). Annual changes of lymphocytes negatively correlated with annual changes of DLCO (r = 0.45 p < 0.02) and D/VA (r = 0.46 p < 0.02).
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Katedry i Kliniki Ftizjopneumonologii Slaskiej Akademii Medycznej w Zabrzu.
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D000293:Adolescent; D000328:Adult; D000542:Alveolitis, Extrinsic Allergic / Q000188:drug therapy* / Q000503:physiopathology; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D005260:Female; D006801:Humans; D018655:Lymphocyte Count / Q000187:drug effects; D016676:Macrophages, Alveolar / Q000166:cytology; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000166:cytology; D011241:Prednisone / Q000494:pharmacology / Q000627:therapeutic use*; D011379:Prognosis; D012129:Respiratory Function Tests
D011241:Prednisone
Ocena przydatności płukania oskrzelowo-pecherzykowego (BAL) w prognozowaniu i monitorowaniu leczenia chorych na przewlekłe alergiczne zapalenie pecherzyków płucnych.