Effect of herba artemisiae scopariae on cytogenetic damage induced by aflatoxin B1.
It was found that the per mill rate of micronucleus of marrow cells in mice induced by AFB1 decreased with the increasing dosage of Herba Artemisiae Scopariae, and that there were dosage-effect relations in the lowering of percentage of chromosomal aberration induced by AFB1 and in the inhibition effect on some sister chromatid exchanges per cell.
Hong
Z
Z
Fujian College of Traditional Chinese Medicine, Fuzhou.
Ye
T
T
Chen
S
S
Liu
L
L
Lin
L
L
D016604:Aflatoxin B1 / Q000633:toxicity*; D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D002869:Chromosome Aberrations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D015162:Micronucleus Tests; D012854:Sister Chromatid Exchange / Q000187:drug effects*
D016588:Anticarcinogenic Agents; D004365:Drugs, Chinese Herbal; D016604:Aflatoxin B1