title: Gastro-oesophageal reflux before and after vertical banded gastroplasty in the treatment of obesity.
abstract: OBJECTIVE
  To study the long term effect of vertical banded gastroplasty on lower oesophageal sphincter pressure.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  University hospital, Sweden.
  
  
  METHODS
  21 morbidly obese patients (mean body mass index 42.5).
  
  
  METHODS
  Vertical banded gastroplasty, together with measurements of endoscopic grade, oesophageal manometry, and 24 hour pH before, and a mean of 38 months after, operation.
  
  
  METHODS
  Weight, grade of oesophagitis according to the Savary-Miller classification, number of episodes of reflux, percentage of time that the pH was < 4, and lower oesophageal sphincter pressure.
  
  
  RESULTS
  Before operation 5/14 patients (36%) had evidence of oesophagitis, and 12/21 (57%) had evidence of reflux disease. Two patients had abnormally low lower oesophageal sphincter pressure ( < 10 mm Hg). A mean (SEM) of 32 months after operation (range 6-49) the mean body mass index was 32.7 (1.2), and after a mean of 38 months paired data showed that there had been no significant changes in manometric (n = 11) or 24 hour pH (n = 10) measurements, or in endoscopic grading (n = 7).
  
  
  CONCLUSIONS
  Vertical banded gastroplasty used in the treatment of morbid obesity does not affect the antireflux function of the lower oesophageal sphincter.
authors: Department of Surgery, Karolinska Institute at Danderyd Hospital, Stockholm, Sweden.
authors: E
authors: E
authors: Näslund
authors: L
authors: L
authors: Granström
authors: A
authors: A
authors: Melcher
authors: D
authors: D
authors: Stockeld
authors: L
authors: L
authors: Backman
mesh_terms: D004942:Esophagitis, Peptic / Q000150:complications / Q000503:physiopathology* / Q000517:prevention & control; D004943:Esophagogastric Junction / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000150:complications / Q000503:physiopathology* / Q000517:prevention & control; D015391:Gastroplasty / Q000379:methods*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000503:physiopathology; D011312:Pressure; D011446:Prospective Studies; D013997:Time Factors