[The mechanism of the action of low doses of thyroid hormones on the stressor-induced changes in rat vascular tonus].
Small doses of thyroidine were found to diminish a 6-hr immobilisation-induced decrease of the mean AP and duration of a hypertension response to blockade of NO-synthasa. The thyroidine seems to act on the system of endothelial nitric oxide synthasa.
Solodkov
A P
AP
Bozhko
A P
AP
D000818:Animals; D013956:Antithyroid Agents / Q000008:administration & dosage*; D001120:Arginine / Q000031:analogs & derivatives / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D003331:Coronary Vessels / Q000187:drug effects / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D066298:In Vitro Techniques; D009129:Muscle Tonus / Q000187:drug effects* / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000503:physiopathology; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D051381:Rats; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000008:administration & dosage*; D013997:Time Factors; D019323:omega-N-Methylarginine
D013956:Antithyroid Agents; D013963:Thyroid Hormones; D019323:omega-N-Methylarginine; C004227:thyroidin; D001120:Arginine; D019001:Nitric Oxide Synthase
K mekhanizmu vliianiia malykh doz tireoidnykh gormonov na stressornye izmeneniia tonusa sosudov krys.