Can we improve diuretic response in heart failure?
Although there have been major advances in the treatment of heart failure, loop diuretics remain essential for the treatment of fluid retention. Patients with refractory heart failure become resistant to progressively larger doses of diuretics. Some of the strategies which may be helpful in restoring diuretic efficacy are reviewed.
Trelawny
J M
JM
Trafford General Hospital, Manchester.
D001581:Benzothiadiazines; D002302:Cardiac Output / Q000187:drug effects; D004039:Diet, Sodium-Restricted; D004231:Diuresis / Q000187:drug effects; D004232:Diuretics / Q000494:pharmacology / Q000627:therapeutic use*; D004234:Diuretics, Osmotic / Q000627:therapeutic use; D004573:Electrolytes / Q000378:metabolism; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D008138:Loop of Henle / Q000187:drug effects; D009318:Natriuresis / Q000187:drug effects; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use
D001581:Benzothiadiazines; D004232:Diuretics; D004234:Diuretics, Osmotic; D004573:Electrolytes; D049993:Sodium Chloride Symporter Inhibitors