title: Molecular recognition in vitamin D-binding protein.
abstract: Vitamin D-binding protein (DBP) or group-specific component (Gc) is a relatively abundant serum protein with multiple functions, the majority of which are initiated by the highly specific recognition and binding of a ligand by this protein. During the past decade and a half, several structure-functional studies have been carried out to shed light on the physiological significance of the multiple functions of DBP. Results of these studies are discussed.
authors: Vitamin D Laboratory, Boston University School of Medicine, Massachusetts 02118, USA.
authors: R
authors: R
authors: Ray
mesh_terms: D000199:Actins / Q000378:metabolism; D000345:Affinity Labels; D000818:Animals; D001665:Binding Sites; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D008024:Ligands; D016215:Macrophage-Activating Factors / Q000378:metabolism; D015394:Molecular Structure; D009154:Mutation; D011485:Protein Binding; D018167:Receptors, Calcitriol / Q000378:metabolism; D014807:Vitamin D / Q000031:analogs & derivatives / Q000378:metabolism; D014809:Vitamin D-Binding Protein / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
chemical_list: D000199:Actins; D000345:Affinity Labels; D005227:Fatty Acids; D008024:Ligands; D016215:Macrophage-Activating Factors; D018167:Receptors, Calcitriol; D014809:Vitamin D-Binding Protein; D014807:Vitamin D