title: Primary spinal leptomeningeal gliomatosis presenting visual disturbance as the initial symptom: case report.
abstract: We report a case of diffuse leptomeningeal gliomatosis which spread from the cervical to the sacral spine. A 60-year-old man was admitted with visual disturbance due to papilledema. Magnetic resonance imaging revealed holocord leptomeningeal gliomatosis without a definite intraparenchymal lesion, and the patient's neurological examination was unremarkable except for papilledema. Intracranial hypertension secondary to spinal tumor is well known but unusual, and the mechanism is still unclear. In our case, an elevated protein concentration of cerebrospinal fluid is suggested as the cause of intracranial hypertension.
authors: Department of Neurosurgery, Keio University, Tokyo, Japan.
authors: M
authors: M
authors: Kobayashi
authors: K
authors: K
authors: Hara
authors: M
authors: M
authors: Nakatsukasa
authors: I
authors: I
authors: Murase
authors: S
authors: S
authors: Toya
mesh_terms: D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D005910:Glioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008578:Meninges / Q000473:pathology; D008875:Middle Aged; D013116:Spinal Cord / Q000473:pathology; D014786:Vision Disorders / Q000209:etiology*