title: Three-dimensional reconstruction of icosahedral particles--the uncommon line.
abstract: The past few years have seen an explosion in the number of viral structures determined by icosahedral reconstruction from cryoelectron micrographs. The success of this work has depended upon a combination of the high-fidelity but low-contrast information contained in these images with efficient algorithms for determining particle orientation and three-dimensional structure. This review describes the principles behind the most commonly used method of reconstruction of the icosahedral particles and the method's implementation in an icosahedral reconstruction program suite.
authors: Structural Biology Programme, European Molecular Biology Laboratory, Heidelberg, Federal Republic of Germany.
authors: S D
authors: SD
authors: Fuller
authors: S J
authors: SJ
authors: Butcher
authors: R H
authors: RH
authors: Cheng
authors: T S
authors: TS
authors: Baker
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D003198:Computer Simulation; D005615:Freezing; D008433:Mathematics; D008854:Microscopy, Electron; D012984:Software