title: ["Cyclosporin dependence" in the treatment of severe aplastic anemia in children].
abstract: Cyclosporin A (CA) was used in the treatment of 2 patients with acquired aplastic anemia. Upon reaching hematological remission these children had recurrence consequent to dose lowering or discontinuation of CA. The remission occurred again when full-dose CA treatment was resumed. Slow 2-year decrease in CA dose led to uneventful end of CA treatment without deterioration of blood picture.
authors: N Iu
authors: NIu
authors: Bogacheva
authors: M M
authors: MM
authors: Shneĭder
authors: A A
authors: AA
authors: Maschan
mesh_terms: D000293:Adolescent; D000741:Anemia, Aplastic / Q000188:drug therapy*; D002648:Child; D016572:Cyclosporine; D006801:Humans; D007166:Immunosuppressive Agents; D008297:Male; D012074:Remission Induction / Q000379:methods; D019966:Substance-Related Disorders
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine
vernacular_title: "Tsikloporinovaia zavisimost'" pri lechenii tiazhelykh aplasticheskikh anemiĭ u deteĭ.