title: [The immune system characteristics during normal aging and in Alzheimer's disease].
abstract: The paper presents a review of data available in the literature and the authors' own findings on age-related physiology and pathology of the immune system. Almost all parameters characterizing the functional activity of the immune system in Alzheimer's disease (AD) were demonstrated to significantly differ from those in the healthy elderly, The magnitude of immunological changes clearly correlated with the severity of dementia in AD patients. A hypothesis of the gradual development of immunological changes in an AD patient in relation to his dementia formation is given.
authors: G I
authors: GI
authors: Koliaskina
authors: T P
authors: TP
authors: Sekirina
authors: L V
authors: LV
authors: Androsova
authors: S G
authors: SG
authors: Kushner
authors: E F
authors: EF
authors: Vasil'eva
authors: O A
authors: OA
authors: Burbaeva
authors: S I
authors: SI
authors: Gavrilova
authors: N D
authors: ND
authors: Selezneva
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000276:immunology*; D000544:Alzheimer Disease / Q000276:immunology*; D006801:Humans; D007107:Immune System / Q000276:immunology*; D007111:Immunity, Cellular; D008875:Middle Aged; D012016:Reference Values
vernacular_title: Osobennosti immunnoĭ sistemy pri normal'nom starenii i pri bolezni Al'tsgeĭmera.