Analysis of CA repeat polymorphisms places three human gene loci on the 8p linkage map.
The gene loci for luteinizing hormone-releasing hormone (LHRH), the beta-3 adrenergic receptor (ADRB3), and heregulin (HGL) have been assigned to the short arm of human chromosome 8, but the positions of these loci on the human genetic linkage map have not been previously reported. We have isolated simple tandem repeat polymorphisms (STRPs) for these loci. These STRPs enabled us to determine the genetic map locations for these genes.
Bruskiewich
R
R
Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
Everson
T
T
Ma
L
L
Chan
L
L
Schertzer
M
M
Giacobino
J P
JP
Muzzin
P
P
Wood
S
S
D001483:Base Sequence; D002874:Chromosome Mapping; D002898:Chromosomes, Human, Pair 8 / Q000235:genetics*; D018900:Dinucleotide Repeats; D005796:Genes; D008040:Genetic Linkage; D006023:Glycoproteins / Q000235:genetics*; D007987:Gonadotropin-Releasing Hormone / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D020880:Neuregulins; D011943:Receptors, Adrenergic, beta / Q000235:genetics*; D022702:Receptors, Adrenergic, beta-3
D006023:Glycoproteins; D020880:Neuregulins; D011943:Receptors, Adrenergic, beta; D022702:Receptors, Adrenergic, beta-3; D007987:Gonadotropin-Releasing Hormone