A scintigraphic study on gastric emptying in patients with non-ulcer dyspepsia.
Solid gastric emptying rates (GER) were determined with scintigraphic techniques in 20 patients with non-ulcer dyspepsia (NUD) and 9 healthy volunteers. GER were significantly decreased in NUD patients compared with controls, especially 45 min (P < 0.05), 60 and 90 min (P < 0.01) and 120 min (P < 0.05) after ingestion. In 13 out of 20 NUD patients who demonstrated lower GER, only 4 cases gave a lower GER at all stages throughout the determination, the other 9 showed their abnormal GER only after 60 min. In 3 cases who received repeated GER studies after cisapride therapy, 2 patients showed symptomatic relief accompanied by GER improvement. It is concluded that gastric emptying delay may be present with a high percentage in patients with non-ulcer dyspepsia. Scintigraphic gastric emptying test is a safe and reliable technique with good reproducibility. It may be helpful in quantitative study about gastric motion disorders.
Wang
S
S
Department of Gastroenterology, Tongji Hospital, Tongji Medical University, Wuhan.
Cheng
B
B
Wu
H
H
Zheng
Y
Y
Hu
J
J
Zhou
J
J
Xianyu
Z
Z
D000293:Adolescent; D000328:Adult; D004415:Dyspepsia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; C026177:technetium phytate; D010833:Phytic Acid