title: Wegener's granulomatosis presenting as major salivary gland enlargement.
abstract: Salivary gland involvement is rare in Wegener's granulomatosis. We report the first case of widespread major salivary gland enlargement as part of the presentation of this disease. A review of the few reported cases in the literature suggests that salivary gland involvement may be associated with a limited form of the disease and an improved prognosis. The anti-neutrophil cytoplasmic antibody (c-ANCA) assay remains the gold standard of diagnosis but care should be exercised in the interpretation of results. This patient responded well to current immunosuppressive therapy.
authors: Department of Otolaryngology, City Hospital, Edinburgh, UK.
authors: K W
authors: KW
authors: Ah-See
authors: K
authors: K
authors: McLaren
authors: A G
authors: AG
authors: Maran
mesh_terms: D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D010309:Parotitis / Q000209:etiology* / Q000473:pathology; D013364:Submandibular Gland Diseases / Q000209:etiology*