title: Inhibition of herpes simplex virus type 1 by aqueous extracts from shoots of Helichrysum aureonitens (Asteraceae).
abstract: Helichrysum aureonitens, a southern African medicinal plant reported to have antibacterial properties, was evaluated for antiviral activity against herpes simplex virus type 1 (HSV-1) in vitro. The crude aqueous extract from shoots of H. aureonitens at a concentration of 1.35 mg/ml (w/v) showed significant antiviral activity on HSV-1 in human lung fibroblasts as demonstrated by the absence of a cytopathic effect.
authors: Department of Botany, University of Pretoria, South Africa. Marion@scientia.up.ac.za
authors: J J
authors: JJ
authors: Meyer
authors: A J
authors: AJ
authors: Afolayan
authors: M B
authors: MB
authors: Taylor
authors: L
authors: L
authors: Engelbrecht
mesh_terms: D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002478:Cells, Cultured; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects* / Q000821:virology; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D006801:Humans; D008168:Lung / Q000166:cytology / Q000187:drug effects* / Q000821:virology; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D018520:Plant Shoots / Q000378:metabolism; D010946:Plants, Medicinal; D013019:South Africa
chemical_list: D000998:Antiviral Agents; D010936:Plant Extracts