title: Ribozymes: structure and mechanism in RNA catalysis.
abstract: The hammerhead RNA is a small catalytic RNA found in a number of RNA virus genomes and virus-like RNAs. The recently determined crystal structures of hammerhead ribozymes reveal how a small RNA motif can fold up into a conformation suitable for mediating RNA cleavage.
authors: MRC Laboratory of Molecular Biology, Cambridge, UK.
authors: W G
authors: WG
authors: Scott
authors: A
authors: A
authors: Klug
mesh_terms: D001483:Base Sequence; D018360:Crystallography, X-Ray; D008274:Magnesium / Q000737:chemistry / Q000378:metabolism; D008670:Metals / Q000494:pharmacology; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry* / Q000378:metabolism; D016337:RNA, Catalytic / Q000737:chemistry* / Q000378:metabolism*; D012367:RNA, Viral / Q000737:chemistry / Q000378:metabolism
chemical_list: D008670:Metals; D016337:RNA, Catalytic; D012367:RNA, Viral; D012313:RNA; D008274:Magnesium