Alport syndrome: clinical experience with 21 paediatric patients.
The clinical, histological and genetic features of Alport syndrome are presented and illustrated by our experience with 21 paediatric patients seen over the last 22 years. From the 15 boys, 7 went into end-stage renal failure before the age of 20 years. In the 6 girls, the symptomatology was limited to permanent haematuria and mild proteinuria.


CONCLUSIONS
Alport syndrome should be included in the differential diagnosis of permanent haematuria even in the absence of any suggestive familial antecedent.
Barten
S
S
Renal Unit, University Hospital Gasthuisberg, Leuven, Belgium.
Proesmans
W
W
D017668:Age of Onset; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood; D003638:Deafness / Q000209:etiology; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D006417:Hematuria / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology; D008297:Male; D009394:Nephritis, Hereditary / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000235:genetics; D010375:Pedigree; D051437:Renal Insufficiency / Q000209:etiology
D003404:Creatinine