title: Fetal hydrops secondary to human parvovirus infection in early pregnancy.
abstract: Parvovirus B19 infection has been associated with fetal anaemia, hydrops, and in some cases demise. Most of the reported cases of fetal hydrops were detected in second-trimester fetuses. We report a series of three cases in which human parvovirus infection was associated with hydropic changes at an earlier gestational age. Spontaneous resolution of hydrops occurred in all fetuses. A greater understanding of the natural history of human parvovirus infection is needed prior to deciding on the mode of therapy (conservative management versus in utero fetal therapy).
authors: Department of Obstetrics and Gynecology, North Shore University Hospital, Manhasset, NY 11030, USA.
authors: B M
authors: BM
authors: Petrikovsky
authors: D
authors: D
authors: Baker
authors: E
authors: E
authors: Schneider
mesh_terms: D000328:Adult; D000649:Amniocentesis; D004279:DNA, Viral / Q000032:analysis; D016731:Erythema Infectiosum / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000209:etiology*; D007075:Immunoglobulin M / Q000276:immunology; D010322:Parvoviridae Infections / Q000150:complications / Q000175:diagnosis*; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis / Q000379:methods*; D011863:Radioimmunoassay; D016216:Ultrasonography, Prenatal
chemical_list: D004279:DNA, Viral; D007075:Immunoglobulin M