title: Aspergillus fumigatus scleritis.
abstract: We report a case of scleritis caused by Aspergillus fumigatus. The infection was successfully treated with antifungal drugs, cryotherapy and dura mater grafting. A 67-year-old man developed a scleral ulcer 2 months after suffering a trauma in his right eye caused by the branch of a tree. Diagnosis was made after biopsy of a scleral nodule. Scrapings showed hyphal fragments and cultures were positive for Aspergillus fumigatus. Although therapy with oral fluconazol and topical amphotericin B was begun, the scleritis continued to worsen, so cryotherapy and dura mater grafting were performed. The patient showed no signs of infection for 8 months after discontinuation of antifungal drugs.
authors: Department of Ophthalmology and Dermatology, University of Santiago de Compostela, Spain.
authors: M T
authors: MT
authors: Rodriguez-Ares
authors: M V
authors: MV
authors: De Rojas Silva
authors: M
authors: M
authors: Pereiro
authors: B
authors: B
authors: Fente Sampayo
authors: G
authors: G
authors: Gallegos Chamas
authors: M
authors: M
authors: S-Salorio
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D017679:Cryotherapy; D004388:Dura Mater / Q000637:transplantation; D015821:Eye Infections, Fungal / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005131:Eye Injuries / Q000382:microbiology / Q000628:therapy; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008297:Male; D015423:Scleritis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole