Influence of fluvoxamine on tacrine metabolism in vitro: potential implication for the hepatotoxicity in vivo.
Becquemont
L
L
Laboratoire de Biochimie Pharmacologique, INSERM U 75, Faculté de Médecine Necker, Paris, France.
Le Bot
M A
MA
Riche
C
C
Beaune
P
P
D056486:Chemical and Drug Induced Liver Injury / Q000517:prevention & control; D019363:Cytochrome P-450 CYP1A1 / Q000037:antagonists & inhibitors; D065609:Cytochrome P-450 CYP1A2 Inhibitors; D004347:Drug Interactions; D016666:Fluvoxamine / Q000494:pharmacology*; D006801:Humans; D008862:Microsomes, Liver / Q000201:enzymology*; D013619:Tacrine / Q000009:adverse effects / Q000378:metabolism*
D065609:Cytochrome P-450 CYP1A2 Inhibitors; D013619:Tacrine; D019363:Cytochrome P-450 CYP1A1; D016666:Fluvoxamine