[Immunophenotyping of childhood leukemias--results of the first 100 bone marrow tests].
The authors used a cell-surface-marker analysis by flow cytometry for immunophenotyping of pediatric leukemia from 1993. Results of their first one-hundred cases were summarized. They examined 68 bone-marrow samples from 58 patients affected by leukemia, and diagnosed 19 acute myeloid leukemia (32%), 5 T-cell acute lymphoid leukemia (8%), 32 B-cell acute lymphoid leukemia (54%) and 2 biphenotypic leukemia (5%). A higher CD34 antigen positivity was found compared to adults. They analysed the incidence and prognostic significance of myeloid + lymphoid leukemia and lymphoid + myeloid leukemia cases. Nondiagnostic and unsuccessful cases were got according to the literature.
Klujber
V
V
Semmelweis Orvostudományi Egyetem Budapest, II. Gyermekklinika.
Koós
R
R
Schuler
D
D
Bocsi
J
J
D000293:Adolescent; D001853:Bone Marrow / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D016130:Immunophenotyping; D007223:Infant; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology
Gyermekkori leukémiák immunfenotipizálása során kapott eredményeink (az elsó 100 csontvelvizsgálat tapasztalatai).