Extrapyramidal disorder secondary to cytomegalovirus infection and toxoplasmosis after liver transplantation.
A boy underwent liver transplantation for postnecrotic cirrhosis secondary to Wilson's disease. The patient had no neurological clinical manifestations prior to the transplantation. The patient developed dysarthria, dysphagia, spasticity, rigidity, and intention and resting tremor of all extremities. Cranial computerized tomography revealed hypodensity of the thalamus, basal ganglia and external capsule. Anti-cytomegalovirus IgM became positive. At autopsy, there were severe pathological changes at the thalamus and basal ganglia.
Coelho
J C
JC
Department of Surgery, Federal University of Paraná, Brazil.
Wiederkehr
J C
JC
Cat
R
R
Carrero
J E
JE
de Oliveira
E D
ED
Campos
A C
AC
Cat
I
I
D000293:Adolescent; D001480:Basal Ganglia Diseases / Q000209:etiology*; D003586:Cytomegalovirus Infections / Q000150:complications*; D006527:Hepatolenticular Degeneration / Q000601:surgery; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D011183:Postoperative Complications; D016781:Toxoplasmosis, Cerebral / Q000150:complications*