Determination of the relationship between the pH and conductivity of gastric juice.
Studies of gastric secretion were carried out on 14 subjects, some of whom had taken acid secretion inhibitors. In vitro studies were performed in an attempt to ascertain the effect of H+ and Na+ ions on conductivity. There is a strong correlation between intragastric pH and conductivity for pH < 2, but none of the gastric samples were isotonic. The measured conductivity of the samples was therefore considerably lower than predicted for isotonic gastric juice.
Watson
S J
SJ
Department of Medical Physics and Clinical Engineering, Royal Hallamshire Hospital, Sheffield, UK.
Smallwood
R H
RH
Brown
B H
BH
Cherian
P
P
Bardhan
K D
KD
D000328:Adult; D000897:Anti-Ulcer Agents / Q000494:pharmacology; D002927:Cimetidine / Q000494:pharmacology*; D004553:Electric Conductivity; D004563:Electrochemistry / Q000379:methods; D004573:Electrolytes / Q000032:analysis*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005750:Gastric Juice / Q000737:chemistry* / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D012964:Sodium / Q000032:analysis
D000897:Anti-Ulcer Agents; D004573:Electrolytes; D002927:Cimetidine; D012964:Sodium