title: Characterization of the formation of interfacially photopolymerized thin hydrogels in contact with arterial tissue.
abstract: The aim of this study was to examine the conditions under which an interfacial photopolymerization process results in hydrogel barriers. Visible light initiated interfacial photopolymerization of a polyoxyethylene glycol (PEG)-co-poly(alpha-hydroxy acid) copolymer based on PEG 8000 macromonomer was performed on porcine aortic tissue, resulting in conformal hydrogel barriers. The process conditions were optimized in vitro for the formation of a 5-100 microns thick barrier.
authors: Focal Inc., Lexington, MA 02173, USA.
authors: M D
authors: MD
authors: Lyman
authors: D
authors: D
authors: Melanson
authors: A S
authors: AS
authors: Sawhney
mesh_terms: D000818:Animals; D001011:Aorta; D001672:Biocompatible Materials; D007700:Kinetics; D009131:Muscle, Smooth, Vascular; D010777:Photochemistry; D011092:Polyethylene Glycols; D013552:Swine; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D011092:Polyethylene Glycols