title: [Synthesis and antibacterial properties of quinoxaline 1,4-dioxide derivatives].
abstract: Novel quinoxaline 1,4-dioxide derivatives were synthesized from benzofuroxans and the enolic form of 1,3-diketones or 3-oxoalkanoic esters or 3-oxoalkanamides or butanedioic esters catalyzed by silica gel or molecular sieves and their antibacterial activities were evaluated. As the results of antibacterial screening tests in vitro, quinoxaline 1,4-dioxides revealed strong activities against Bacteroides fragilis.
authors: College of Pharmacy, Nihon University, Chiba, Japan.
authors: T
authors: T
authors: Takabatake
authors: Y
authors: Y
authors: Takabatake
authors: T
authors: T
authors: Miyazawa
authors: M
authors: M
authors: Hasegawa
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D011810:Quinoxalines