[Use of propofol (diprivan) for induction of anesthesia in neurosurgical patients. I. Pressor reaction to laryngoscopy and intubation of the trachea].
Pressor reaction to laryngoscopy and intubation of the trachea was studied in 32 patients with neurosurgical diseases of the brain (supratentorial tumors and arterial aneurysms) under conditions of induction anesthesia with propofol (diprivan) in the mean dose of 2.85 mg/kg. Diprivan alone did not block the development of pronounced pressor reaction to intubation. Combination of diprivan in the same dose with dipidolor (0.4 mg/kg) ensured complete blocking of the pressor reaction in neurosurgical patients. Combination of diprivan and fentanyl (2.85 mg/kg) blocked the development of a pressor reaction not so effectively and not in all the examinees.
Tseĭtlin
A M
AM
Lubnin
A Iu
AIu
Baranov
O A
OA
Luk'ianov
V I
VI
D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000494:pharmacology; D000758:Anesthesia; D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D001932:Brain Neoplasms / Q000601:surgery*; D002941:Circle of Willis; D004338:Drug Combinations; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery*; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D007828:Laryngoscopy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010892:Pirinitramide / Q000008:administration & dosage / Q000494:pharmacology; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology*
D000701:Analgesics, Opioid; D018686:Anesthetics, Intravenous; D004338:Drug Combinations; D010892:Pirinitramide; D015742:Propofol
Primenenie propofola (diprivana) dlia induktsii anestezii u neĭrokhirurgicheskikh bol'nykh. I. Pressornaia reaktsiia na laringoskopiiu i intubatsiiu trakhei.