title: Therapeutic cup insemination with cryopreserved donor sperm: prognostic value of cervical mucus score at insemination and the number of motile sperm in mucus at 24 hours.
abstract: OBJECTIVE
  To examine the prognostic value of cervical mucus score at insemination and the number of motile sperm in mucus 24 hours after therapeutic cup insemination with cryopreserved donor sperm.
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  Academic tertiary medical center.
  
  
  METHODS
  One hundred thirty-eight women with confirmed bilateral tubal patency who received therapeutic cup inseminations with cryopreserved donor sperm between 1986 and 1993.
  
  
  METHODS
  All insemination cycles were monitored with serial daily urinary LH determinations with a single (n = 312) insemination or two inseminations (n = 212) performed on and/or 1 day after the day of LH surge detection. A single examiner assigned cervical mucus scores in all insemination cycles and recorded the number of motile sperm in mucus 24 hours after the first insemination in dual insemination cycles.
  
  
  METHODS
  Pregnancy rate during various cervical mucus and motile sperm scores.
  
  
  RESULTS
  Ninety-one women conceived (66%) and seven of these achieved two pregnancies. The overall pregnancy rate per insemination cycle was 18.7%. Age and day of insemination were the only variables identified as having significant influence on cycle outcome. Pregnancy occurred with decreasing frequency as patient age increased and was nearly twice as likely after insemination on the day after the urinary LH surge as on the day of surge detection.
  
  
  CONCLUSIONS
  Insemination the day after the urinary LH surge is superior to the day of surge detection. Cervical mucus score and the number of motile sperm in mucus 24 hours after therapeutic cup insemination with cryopreserved donor sperm do not correlate with cycle outcome.
authors: Department of Obstetrics and Gynecology, University of North Carolina School of Medicine 27599-7570, USA.
authors: W R
authors: WR
authors: Meyer
authors: P M
authors: PM
authors: Smith
authors: M R
authors: MR
authors: Clark
authors: L L
authors: LL
authors: Cusmano
authors: M A
authors: MA
authors: Fritz
mesh_terms: D000328:Adult; D000375:Aging / Q000502:physiology; D002582:Cervix Mucus / Q000502:physiology*; D015925:Cryopreservation; D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D007986:Luteinizing Hormone / Q000652:urine; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D011379:Prognosis; D012189:Retrospective Studies; D012662:Semen Preservation / Q000379:methods*; D013081:Sperm Motility / Q000502:physiology*; D013094:Spermatozoa / Q000166:cytology / Q000502:physiology; D013997:Time Factors
chemical_list: D007986:Luteinizing Hormone