Three cases of eosinophilic lymphfolliculoid granuloma of the soft tissue originating from the parotid gland.
Two women aged 33 and 57 years respectively, and a man aged 40 years visited our hospital complaining of swelling of the parotid gland region. The diagnosis of eosinophilic lymphfolliculoid granuloma of the soft tissue (Kimura's disease) based on laboratory findings was made in all 3 cases. Patient 1 received radiation therapy followed by surgery, and Patients 2 and 3 were treated with antiallergics and antiinflammatory agents after surgery. Satisfactory results were obtained in all cases. Although Kimura's disease is a benign tumor, no established therapy is available so far, and a high recurrence rate is the major concern. Based on our experience and treatments reported in the literature, we conclude that a combination therapy consisting mainly of surgery is the most effective treatment of Kimura's disease.
Mitsui
M
M
Department of Otolaryngology, St. Marianna University School of Medicine, Kawasaki, Japan.
Ogino
S
S
Ochi
K
K
Ohashi
T
T
D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000175:diagnosis* / Q000601:surgery*; D004804:Eosinophils / Q000648:ultrastructure*; D005260:Female; D006099:Granuloma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000473:pathology* / Q000601:surgery*