title: Triggering of ovulation by a gonadotropin-releasing hormone (GnRH) agonist in patients pretreated with a GnRH antagonist.
abstract: OBJECTIVE
  To determine if GnRH-agonist (GnRH-a) could induce a LH surge in patients where a GnRH antagonist was used to prevent premature spontaneous LH surge.
  
  
  METHODS
  Pilot study.
  
  
  METHODS
  Five patients treated with ovarian stimulation and IUI for idiopathic infertility.
  
  
  METHODS
  Luteinizing hormone, FSH, and P plasma levels.
  
  
  RESULTS
  A LH and FSH surge as well as a P rise were obtained in the five patients studied.
  
  
  CONCLUSIONS
  A GnRH-a successfully can induce an LH surge after GnRH antagonist administration. The effect of the antagonist on the quality of the GnRH-a-induced LH surge as well as the oocyte quality remain to be evaluated.
authors: Department of Obstetrics and Gynecology, Antoine Béclère Hospital, Clamart, France.
authors: F
authors: F
authors: Olivennes
authors: R
authors: R
authors: Fanchin
authors: P
authors: P
authors: Bouchard
authors: J
authors: J
authors: Taieb
authors: R
authors: R
authors: Frydman
mesh_terms: D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists* / Q000037:antagonists & inhibitors*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D010062:Ovulation Induction; D010865:Pilot Projects; D011374:Progesterone / Q000097:blood
chemical_list: D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone