[The classes, structures, functions and signaling transduction of cytokine receptors].
There are many kinds of cytokine receptors that belong to different receptor families. Most cytokine receptors function as: (1) receptor tyrosine kinase and tyrosine-kinase-associated receptor; (2) receptor serine/threonine kinase; (3) G-protein linked receptor. Following binding with cytokines and activation, the receptors trigger different cascade of intracellular protein phosphorylation to transduction signals, thereby altering the cell's pattern of gene expression and leading to biological effects.
Lu
J
J
Department of Pathophysiology, Second Military Medical University, Shanghai.
D000818:Animals; D018121:Receptors, Cytokine / Q000737:chemistry* / Q000145:classification / Q000502:physiology*; D015398:Signal Transduction
D018121:Receptors, Cytokine