[The effects of retinoic acid on the ultrastructure of cultured fibroblasts].
The paper reports the effects of retinoic acid on the ultrastructure of cultured fibroblasts. Electron microscopic observation (SEM and TEM) showed that fibrous substances on the cell surface and outside the cell had decreased. The results indicated that retinoic acid inhibits collagen synthesis of fibroblasts. The possible mechanism of the effect of retinoic acid in the treatment of scar is discussed.
Song
W
W
Plastic Surgery Hospital, Beijing.
Guan
Z
Z
Sun
G
G
D003094:Collagen / Q000096:biosynthesis; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D014212:Tretinoin / Q000494:pharmacology*
D014212:Tretinoin; D003094:Collagen