title: Forceful epidural injections for the treatment of lumbosciatic pain with post-operative lumbar spinal fibrosis.
abstract: OBJECTIVE
  To evaluate the efficacy of forceful epidural corticosteroid injections in lumbosciatic pain ascribed to post-operative lumbar spinal fibrosis.
  
  
  METHODS
  Randomized controlled study comparing forceful injections via the sacral hiatus of 125 mg prednisolone acetate + 40 ml saline (treatment group) and injections via the same route of 125 mg prednisolone acetate alone (control group). Results were compared after six and 18 months. The main evaluation criterion was a subjective assessment of overall efficacy done by the patient using a seven-level scale.
  
  
  RESULTS
  After six months, the proportion of patients who were relieved of their sciatica was significantly higher in the forceful injection group (n = 29; 45%) than in the control group (n = 31; 19%) (p = 0.03). Success rates for low back pain were 29% and 6% in the forceful injection and control groups, respectively. Among secondary efficacy criteria, nerve root pain evaluated on a visual analog scale and by Schöber's index showed significantly greater improvement in the forceful injection group than in the control group. After 18 months, results were still in favor of the forceful injection group, with success rates of 39% for the sciatica and 31% for the low back pain. The proportion of patients who returned to work was similar in the two groups.
  
  
  CONCLUSIONS
  Although mediocre overall, the results of forceful epidural corticosteroid injections are better than those of simple epidural injections of a corticosteroid alone. Given the paucity of effective treatments for lumbosciatic pain apparently due to postoperative fibrosis, forceful injections should be given a place in the treatment of this condition.
authors: Department of Rehabilitation and Readaptation of Patients with Locomotor and Spinal Disorders, Cochin Teaching Hospital, Paris, France.
authors: M
authors: M
authors: Revel
authors: G R
authors: GR
authors: Auleley
authors: S
authors: S
authors: Alaoui
authors: M
authors: M
authors: Nguyen
authors: T
authors: T
authors: Duruoz
authors: S
authors: S
authors: Eck-Michaud
authors: C
authors: C
authors: Roux
authors: B
authors: B
authors: Amor
mesh_terms: D000328:Adult; D017586:Diskectomy; D004311:Double-Blind Method; D005260:Female; D005355:Fibrosis; D006801:Humans; D007268:Injections, Epidural; D007796:Laminectomy; D008159:Lumbar Vertebrae / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D010149:Postoperative Pain / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D012008:Recurrence; D012585:Sciatica / Q000188:drug therapy*; D012965:Sodium Chloride / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D012965:Sodium Chloride; C009935:prednisolone acetate; D011239:Prednisolone