title: Mechanisms involved in the generation of free radicals.
abstract: Free radicals are constantly formed in the human body, both by "accidents of chemistry" and for useful metabolic purposes. Their action is opposed by a balanced and co-ordinated system of antioxidant defences. Upsetting this balance causes oxidative stress, which can lead to cell injury and death.
authors: Pharmacology Group, University of London King's College.
authors: B
authors: B
authors: Halliwell
mesh_terms: D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism* / Q000633:toxicity; D017665:Hydroxyl Radical / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism* / Q000633:toxicity; D016877:Oxidants / Q000378:metabolism*; D018384:Oxidative Stress / Q000502:physiology*; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism* / Q000633:toxicity
chemical_list: D016877:Oxidants; D013481:Superoxides; D009569:Nitric Oxide; D017665:Hydroxyl Radical; D006861:Hydrogen Peroxide; D013482:Superoxide Dismutase