title: Nucleotide sequence of exons 5 to 9 of the p53 tumour-suppressor gene of the donkey (Equus asinus).
abstract: The evolutionary conserved region of the equine homologue of the p53 gene from the donkey genome was PCR amplified and cloned. The 1380 bp fragment consisted of exons 5 to 9 and the intervening introns. The exonic and intronic DNA sequences showed a variable but high level of homology with previously published human sequences. The aminoacid sequences corresponding to the evolutionary conserved domains II, III, and V were identical to the human regions, whilst domain IV was 96% homologous.
authors: Department of Veterinary Medicine, University of Glasgow Veterinary School, Scotland, United Kingdom.
authors: L
authors: L
authors: Nasir
authors: S W
authors: SW
authors: Reid
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018397:Equidae / Q000235:genetics*; D005091:Exons; D016158:Genes, p53; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction