Down syndrome and moyamoya disease: presentation with subarachnoid hemorrhage.
Moyamoya disease in childhood is frequently accompanied by manifestations of ischemia; cerebral hemorrhage is unusual in patients younger than 15 years of age. Previous studies suggest an association of childhood moyamoya disease, which is often bilateral, with Down syndrome. Possible etiologic factors of moyamoya disease in Down syndrome are discussed.
Aylett
S E
SE
Department of Child Health, St. Georges Hospital Medical School, London, United Kingdom.
Britton
J A
JA
De Sousa
C M
CM
D000293:Adolescent; D002533:Cerebral Angiography; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D009072:Moyamoya Disease / Q000150:complications* / Q000000981:diagnostic imaging; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*