title: [Treatment with human recombinant erythropoietin and nutritional status of patients on lon term dialysis].
abstract: In order to assess the effect of long term erythropoietin (EPO) therapy on the nutritional status of hemodialysed (HD) patients 2 groups of HD patients were studied: I-EPO treated for 72 +/- 8 mo, 12 patients, HD for 138 +/- 66 mo, II-control group, 14 patients with Ht 30%, HD for 121 +/- 35 mo. At the onset and after 6 years of follow up patients underwent the following examination: length, body weight, body mass index, body fat stores, arm muscle circumference and total serum protein, serum albumin, lymphocyte count, creatinine, urea, cholesterol and PTH. In EPO group mean BMI, body fat, arm muscle circumference, visceral protein and total lymphocyte count were not change. In control group the decrease in height, body weight, BMI, body fat stores, arm muscle circumference and albumin were observed. Elevation of PTH estimated in half of patients in EPO group and 75% of patients in control group could influence the nutritional status of hemodialysed patients.
  
  
  CONCLUSIONS
  1. Nutritional status of majority of hemodialysed patients was not change during six years EPO therapy. 2. Non EPO treated patients showed the decrease of anthropometric measurements and serum albumin.
authors: Z Katedry i Kliniki Nefrologii, Akademii Medycznej we Wrocławiu.
authors: M
authors: M
authors: Boratyńska
authors: M
authors: M
authors: Magott
authors: Z
authors: Z
authors: Szewczyk
mesh_terms: D000328:Adult; D000886:Anthropometry; D004334:Drug Administration Schedule; D004921:Erythropoietin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D006435:Renal Dialysis; D012709:Serum Albumin / Q000378:metabolism
chemical_list: D012709:Serum Albumin; D004921:Erythropoietin
vernacular_title: Leczenie ludzka rekombinowana erytropoetyna a stan odzywienia chorych długotrwale dializowanych.