title: [Impact of anesthetic technic (general anesthesia versus intradural anesthesia) on the immune status].
abstract: OBJECTIVE
  To study changes in the immune system appearing after general and regional (intradural anesthesia).
  
  
  METHODS
  Fifty patients scheduled for elective surgery to repair inguinal hernias were studied. The patients were randomly assigned to 2 groups: group A patients received general anesthesia and group B patients received intradural anesthesia. Blood was extracted 5 times to determine levels of lymphocytes, activated T cells and B lymphocytes, and T-suppressant activity: t0 (before surgery), t1 (1 h), t2 (4 h), t3 (24 h) y t4 (7 days).
  
  
  RESULTS
  The patients in group A showed slight increases in T lymphocytes, activated T lymphocytes and B lymphocytes, whereas T-suppressant activity decreased significantly. All lymphoid population decreased in group B. Baseline levels had recovered in both groups by 7 days after surgery.
  
  
  CONCLUSIONS
  Anesthetic procedures have an effect on immune responses but the impact is only temporary.
authors: Servicio de Anestesiología y Reanimación, Hospital Universitario de Salamanca.
authors: C
authors: C
authors: Muriel
authors: A
authors: A
authors: García-Sánchez
authors: F
authors: F
authors: Sánchez
authors: A
authors: A
authors: Zaballos
authors: J
authors: J
authors: Nicolás
authors: G
authors: G
authors: Mella
authors: E
authors: E
authors: Sánchez
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D000775:Anesthesia, Spinal; D006801:Humans; D007107:Immune System; D008875:Middle Aged
vernacular_title: Influencia de la técnica anestésica (anestesia general frente a raquianestesia) en el estado inmunológico.