title: An Epstein-Barr virus-associated lymphoproliferative lesion of the skin presenting as recurrent necrotic papulovesicles of the face.
abstract: We describe four patients with lymphoproliferative lesions confined to the skin for several years. They presented with recurrent necrotic papulovesicles of the face. Latent Epstein-Barr virus (EBV) infection was detected in the lymphoid cells from the skin lesions by in situ hybridization. The disease in three patients progressed to T-cell lymphoma. We believe that these patients represent a subset of peripheral T-cell lymphoma with a tendency to localize in the skin.
authors: Department of Dermatology, Seoul National University College of Medicine, Korea.
authors: K H
authors: KH
authors: Cho
authors: C W
authors: CW
authors: Kim
authors: D Y
authors: DY
authors: Lee
authors: S J
authors: SJ
authors: Sohn
authors: D W
authors: DW
authors: Kim
authors: J H
authors: JH
authors: Chung
mesh_terms: D000293:Adolescent; D000328:Adult; D002471:Cell Transformation, Neoplastic; D002648:Child; D002675:Child, Preschool; D005148:Facial Dermatoses / Q000209:etiology* / Q000473:pathology / Q000821:virology; D006566:Herpesviridae Infections / Q000150:complications*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000209:etiology / Q000821:virology; D008232:Lymphoproliferative Disorders / Q000209:etiology* / Q000473:pathology / Q000821:virology; D008297:Male; D012008:Recurrence; D017193:Skin Diseases, Viral / Q000209:etiology* / Q000473:pathology / Q000821:virology; D012878:Skin Neoplasms / Q000209:etiology / Q000821:virology; D014412:Tumor Virus Infections / Q000150:complications*