[Melkersson-Rosenthal syndrome treated by thalidomide. 2 cases].
BACKGROUND
Treatment of Melkersson-Rosenthal syndrome (MRS) remains uncertain. Two cases of MRS treated with thalidomide are described.


METHODS
Two patients with cheilitis granulomatosa and recurrent facial edema have been treated with thalidomide (100 mg daily) for 3 and 6 months respectively. The efficacy of thalidomide was complete clinically and histologically in one case. In the second one, thalidomide suppressed attacks of facial edema and reduced lip swelling.


CONCLUSIONS
These cases suggest a therapeutic effect of thalidomide in MRS.
Safa
G
G
Clinique Dermatologique, Hôpital Charles-Nicolle, Rouen.
Joly
P
P
Boullie
M C
MC
Thomine
E
E
Lauret
P
P
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008556:Melkersson-Rosenthal Syndrome / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D013792:Thalidomide / Q000627:therapeutic use*; D016896:Treatment Outcome
D013792:Thalidomide
Syndrome de Melkersson-Rosenthal traité par le thalidomide. Deux observations.