[Overview of clinical studies with ipriflavone].
Since the discovery and preclinical testing numerous clinical trials have been performed with ipriflavone. It seems that four basic periods of time could be considered as steps of clinical development. Between the late seventies and early eighties the first steps have been taken in Hungary. Based on the promising results clinical studies were performed in Japan by Takeda. Since ipriflavone has proved to be efficacious in preventing bone loss the drug had been registered in Japan. In the late eighties the clinical development started in Italy by Chiesi. As the results were similarly positive ipriflavone has been registered in 1991. Realizing the important changes both in the scientific and regulatory fields Chinoin itself and also in cooperation with Chiesi has been continuing the clinical development process in order to fulfill the presently generally accepted criteria.
Attila
B K
BK
Chinoin Gyógyszer-és Vegyészeti Termékek Gyára Rt, Budapest.
D002986:Clinical Trials as Topic; D006801:Humans; D006814:Hungary; D007529:Isoflavones / Q000627:therapeutic use*; D007564:Japan; D010024:Osteoporosis / Q000517:prevention & control*
D007529:Isoflavones; C018986:ipriflavone
Az ipriflavon klinikai vizsgálatai.