A digital feedback controller application for studying photoreceptor adaptation by 'voltage clamp by light'.
We present a new digital feedback application for the study of the sensitivity characteristics of photoreceptors. The amplitude of the recorded membrane voltage of a cell is steered by changing the incoming light intensity with a motor-driven circular, linear neutral-density wedge (CFW). The voltage response is sampled and fed to a software position controller of the CFW. The controller determines the position of the wedge according to the desired (command) value of the response. The light intensity changes during steady-state represent the sensitivity change, the time-course of adaptation.
Djupsund
K
K
Department of Physiology, University of Oulu, Finland.
Kouvalainen
E
E
Järvilehto
M
M
Weckström
M
M
D000818:Animals; D004553:Electric Conductivity; D005074:Evoked Potentials, Visual; D006135:Gryllidae; D008027:Light; D008433:Mathematics; D010786:Photoreceptor Cells / Q000502:physiology*; D011896:Rana temporaria; D014978:Xenon
D014978:Xenon