title: Are homosexual males a risk group for hepatitis A infection in intermediate endemicity areas?
abstract: The purpose of this study was to examine the prevalence of antibody against hepatitis A (anti-HAV) in a population of homosexual men compared with that of heterosexual men in an area of intermediate HAV endemicity (Madrid, Spain). A total of 148 patients were recruited in a Sexually Transmitted Diseases Clinic: 74 homosexuals (mean age of 28 +/- 5 years) and 74 heterosexuals (29 +/- 5 years). The prevalence of anti-HAV antibody was 47% and 43% for homo- and heterosexuals, respectively. Among the factors evaluated (age, sexual orientation and practices, travel to high HAV endemicity areas) oral-anal contact was significantly associated with a higher prevalence of anti-HAV antibody (odds ratio, 2.8; 95% confidence interval, 1.1-7.4; P = 0.03). These results indicated that in an area of intermediate endemicity young homosexual men are not at increased risk of having acquired hepatitis A infection than heterosexuals. Oral-anal contact is an independent risk factor that influences the presence of anti-HAV antibody, regardless of sexual orientation.
authors: Sandoval Sexually Transmitted Diseases Centre, Autonomous Community, Madrid, Spain.
authors: J
authors: J
authors: Ballesteros
authors: R
authors: R
authors: Dal-Ré
authors: A
authors: A
authors: González
authors: J
authors: J
authors: del Romero
mesh_terms: D000328:Adult; D006506:Hepatitis A / Q000453:epidemiology* / Q000276:immunology; D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies / Q000097:blood; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D012307:Risk Factors; D012725:Sexual Behavior; D013030:Spain / Q000453:epidemiology
chemical_list: D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies