[Detection of dystrophin gene mutation carrier state].
RFLP polymorphism and the sequence of repeated CA were analysed by means of polymerase chain reaction in 62 families in which cases of DMD/BMD had occurred. The established carriers were suggested to undergo prenatal examinations for avoiding giving birth to a child with Duchenne or Becker type of muscular dystrophy.
Bisko
M
M
Zakładu Genetyki, Instytutu Psychiatrii i Neurologii w Warszawie.
Zimowski
J G
JG
Fidziańska
E
E
Badurska
B
B
Fidziańska
A
A
Hausmanowa-Petrusewicz
I
I
Zaremba
J
J
D016189:Dystrophin / Q000235:genetics*; D005260:Female; D006580:Genetic Carrier Screening; D006801:Humans; D008297:Male; D009136:Muscular Dystrophies / Q000235:genetics*; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D012737:Sex Factors; D014960:X Chromosome
D016189:Dystrophin
Wykrywanie nosicielstwa mutacji genu dystrofiny.