title: Biomarker assessment of the effects of petroleum refinery contamination on channel catfish.
abstract: A suite of biomarkers was used to evaluate acute (1- and 7-day) heavy metal-induced toxicity in channel catfish, Ictalurus punctatus, caged at an abandoned petroleum refinery and a non-contaminated reference site. Assays performed include indicators of metabolic, hematological, osmoregulatory, and genotoxic stress. Two cage designs were utilized to evaluate the importance of exposure routes: one allowing exclusive contact with the water column and the other allowing contact with water and sediments. Data collected at 1 and 7 days postexposure indicated that the experimental fish were stressed, having significant increases in blood glucose. After 7 days of exposure, two hemodynamic parameters, hemoglobin and delta-aminolevulinic acid dehydratase, were significantly increased. There were no significant differences observed in other parameters measured.
authors: Zoology Department, Oklahoma State University, Stillwater 74078, USA.
authors: L K
authors: LK
authors: Martin
authors: M C
authors: MC
authors: Black
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D002712:Chlorides / Q000097:blood; D003300:Copper / Q000378:metabolism / Q000633:toxicity; D004249:DNA Damage; D005618:Fresh Water / Q000737:chemistry; D006454:Hemoglobins / Q000187:drug effects / Q000378:metabolism; D007059:Ictaluridae / Q000097:blood* / Q000378:metabolism; D007220:Industrial Waste; D007854:Lead / Q000378:metabolism / Q000633:toxicity; D008099:Liver / Q000378:metabolism; D008670:Metals / Q000378:metabolism / Q000633:toxicity*; D009994:Osmolar Concentration; D010578:Petroleum / Q000633:toxicity*; D000623:Porphobilinogen Synthase / Q000097:blood / Q000187:drug effects; D011786:Quality Control; D012016:Reference Values; D014874:Water Pollutants, Chemical / Q000378:metabolism / Q000633:toxicity*; D015032:Zinc / Q000378:metabolism / Q000633:toxicity
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D002712:Chlorides; D006454:Hemoglobins; D007220:Industrial Waste; D008670:Metals; D010578:Petroleum; D014874:Water Pollutants, Chemical; D007854:Lead; D003300:Copper; D000623:Porphobilinogen Synthase; D015032:Zinc