Felbamate overdose: a case report and discussion of a new antiepileptic drug.
Felbamate was approved in July 1993 for use alone or in combination with other antiepileptic drugs for partial seizures and Lennox-Gastaut syndrome. We report an overdose of felbamate in a teenage female patient who, in a suicide gesture, ingested eight times her maximum dose and suffered only mild side effects. This first report of a felbamate overdose is presented and followed by a discussion of felbamate's effectiveness, pharmacology, adverse effects, and drug interactions.
Nagel
T R
TR
Department of Pediatrics, University of Utah, Salt Lake City, USA.
Schunk
J E
JE
D000293:Adolescent; D000927:Anticonvulsants / Q000494:pharmacology / Q000506:poisoning* / Q000627:therapeutic use; D062787:Drug Overdose; D000078328:Felbamate; D005260:Female; D006801:Humans; D048448:Phenylcarbamates; D011409:Propylene Glycols / Q000494:pharmacology / Q000506:poisoning* / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy; D013406:Suicide, Attempted
D000927:Anticonvulsants; D048448:Phenylcarbamates; D011409:Propylene Glycols; D000078328:Felbamate