Disseminated nontuberculous mycobacteriosis caused by mycobacterium kansasii in a patient with myelodysplastic syndrome.
A 38-year-old man with pancytopenia due to myelodysplastic syndrome exhibited persistent pyrexia and mediastinal lymphadenopathy. A biopsy specimen of the lymph nodes showed diffuse infiltration of epitheloid cells, including acid-fast bacilli identified as Mycobacterium kansasii. Cultures from gastric lavage and stool yielded M. kansasii, and granulomas were found in the bone marrow. A diagnosis of disseminated nontuberculous mycobacteriosis (DNTM) was established. The patient's condition improved after treatment with isoniazid, rifampicin, ethambutol and granulocyte colony-stimulating factor. Although DNTM due to M. kansasii is rare in Japan, it should be recognized as a possible cause of opportunistic infections.
Komeno
T
T
Division of Hematology, University of Tsukuba.
Itoh
T
T
Ohtani
K
K
Kamoshita
M
M
Hasegawa
Y
Y
Hori
M
M
Kobayashi
T
T
Nagasawa
T
T
Abe
T
T
D000328:Adult; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000175:diagnosis; D009190:Myelodysplastic Syndromes / Q000150:complications*; D009894:Opportunistic Infections / Q000150:complications* / Q000175:diagnosis