Inhaled steroids: effect on intraocular pressure in patients without glaucoma.
OBJECTIVE
To evaluate the risk of intraocular pressure (IOP) elevation in patients receiving inhaled steroid therapy.


METHODS
Prospective study.


METHODS
Four private practices in New Jersey.


METHODS
A total of 187 patients (99 men and 88 women) with no documented history of glaucoma about to begin inhaled steroid therapy for various pulmonary conditions were enrolled. Of the 187, 183 were followed at 12 weeks.


METHODS
Measurement of the IOP with the Tono-Pen before therapy was started and 12 weeks after therapy was started.


METHODS
IOP.


RESULTS
No significant rise in IOP was observed. No patient had a rise in IOP greater than 4 mm Hg.


CONCLUSIONS
Although isolated case reports indicate a definite risk of glaucoma in the presence of inhaled steroid therapy, the risk appears to be small.
Samiy
N
N
Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
Walton
D S
DS
Dreyer
E B
EB
D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D005260:Female; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013256:Steroids / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use
D013256:Steroids