Severe barbiturate withdrawal syndrome in migrainous patients.
Three patients who presented with grand mal seizures and an associated behavioral disorder were recognized as suffering from a severe butalbital withdrawal syndrome. All were migraineurs who had become dependent on barbiturates. We propose that the occurrence of seizures, psychotic behavior, or a recent personality change should be considered clues to possible barbiturate abuse in patients with migraine.
Raja
M
M
Dipartimento di Salute Mentale, Ospedale Santo Spirito, Roma, Italy.
Altavista
M C
MC
Azzoni
A
A
Albanese
A
A
D000328:Adult; D001463:Barbiturates / Q000008:administration & dosage / Q000009:adverse effects*; D004827:Epilepsy / Q000139:chemically induced*; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000139:chemically induced; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D013375:Substance Withdrawal Syndrome; D019966:Substance-Related Disorders
D001463:Barbiturates; C004470:butalbital