[An analysis of the DNA sequence in the region of the breakpoint of the T(1;2)dor(var7) translocation inducing the mosaic-type position effect in Drosophila melanogaster].
The sites of location of (AC/GT) minisatellite sequence were detected in 2B region of X-chromosome of Drosophila melanogaster. The distribution of (AC/GT) repeats coincided with the location of one-half of the mapped breakpoints of known rearrangements within this region. Analysis of sequences neighbouring the breakpoints of the rearrangement T(1;2)dor(var7) demonstrated that the breaks between two sequences of (AC/GT) repeats occurred at a distance 80 and 156 bp, respectively, but there were no (AC/GT) repeats in r combination directly. T-rich sequences 25 bp long as well as short tandem repeats were found near the breakpoints. The pentanucleotide repeat (CTGTT)10 is located at a distance of 660 bp from the breakpoint. It differs by one nucleotide from the sequence of the GTGTT satellite attached to the 1A-2B fragment of X-chromosome as a result of rearrangement.
Makunin
I V
IV
Zakharkin
S O
SO
Kokoza
E V
EV
Pokholkova
G V
GV
Kholodilov
N G
NG
Zhimulev
I F
IF
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics*; D004331:Drosophila melanogaster; D008969:Molecular Sequence Data; D009030:Mosaicism / Q000235:genetics*; D010641:Phenotype; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics; D017422:Sequence Analysis, DNA; D014178:Translocation, Genetic / Q000235:genetics*; D014960:X Chromosome / Q000235:genetics
D004247:DNA
Analiz posledovatel'nosti DNK v raĭone tochki razryva translokatsii T(1;2)dor(var7), vyzyvaiushcheĭ éffekt polozheniia mozaichnogo tipa u Drosophila melanogaster.