Mycotoxins transmitted into beer from contaminated grains during brewing.
Studies with aflatoxin B1, ochratoxin A, zearalenone, deoxynivalenol, and fumonisins B1 and B2 added at various stages of the brewing process show that these mycotoxins (or metabolites) may be transmitted from contaminated grains into beer. Citrinin does not survive the mashing step. Mycotoxins in beer could originate from the malted grain or from adjuncts. Although high incidences and concentrations of aflatoxins and zearalenone have been found in local beers brewed in Africa, aflatoxins have not been detected in European beers. Zearalenone and alpha- or beta-zearalenol (the metabolite likely to occur) have not been found in Canadian and European beers, except for one sample analyzed by thin-layer chromatography only. Ochratoxin A rarely has been detected at > 1 ng/mL in beer; liquid chromatographic methods with a 0.05-0.1 ng/mL detection limit, however, have shown moderately high incidences of trace levels. Deoxynivalenol, which survives the brewing process, has been found with high incidence in Canadian and European beers, with concentration of > 200 ng/mL reported in several German beers. Fumonisins B1 and B2 occur to a limited extent in beer.
Scott
P M
PM
Health Canada, Health Protection Branch, Sir Frederick G. Banting Research Centre, Ottawa, ON, Canada.
D016604:Aflatoxin B1 / Q000032:analysis / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000378:metabolism; D001515:Beer / Q000032:analysis* / Q000382:microbiology; D002264:Carboxylic Acids / Q000032:analysis / Q000378:metabolism; D002273:Carcinogens / Q000032:analysis* / Q000378:metabolism; D002853:Chromatography, Liquid; D002953:Citrinin / Q000378:metabolism; D002523:Edible Grain / Q000737:chemistry; D005506:Food Contamination; D005511:Food Handling; D037341:Fumonisins; D009183:Mycotoxins / Q000032:analysis* / Q000378:metabolism; D009793:Ochratoxins / Q000032:analysis / Q000378:metabolism; D014255:Trichothecenes / Q000032:analysis / Q000378:metabolism; D015025:Zearalenone / Q000032:analysis / Q000378:metabolism
D000900:Anti-Bacterial Agents; D002264:Carboxylic Acids; D002273:Carcinogens; D037341:Fumonisins; D009183:Mycotoxins; D009793:Ochratoxins; D014255:Trichothecenes; C056934:fumonisin B2; C025589:ochratoxin A; D002953:Citrinin; C056933:fumonisin B1; D015025:Zearalenone; D016604:Aflatoxin B1; C007262:deoxynivalenol