The investigation of different cameras for in-beam PET imaging.
In situ and in vivo treatment plan verification and beam monitoring as well as dose control during heavy-ion tumour therapy can be performed in principle by measurements of range distributions of beta(+)-emitting nuclei by means of PET techniques. For this purpose the performance of different types of positron camera as well as the results of in-beam PET experiments using beams of beta(+)-active heavy ions (15O, 17F and 19Ne with energies of 300-500 A MeV) are presented. Following the deduced performance requirements a PET scanner that is designed for clinical use in experimental heavy-ion therapy at GSI Darmstadt has been built. This limited angle tomograph consists of two large-area detector heads based on position sensitive BGO detectors and is predicted to perform the measurement of the end point of a beta(+)-emitting ion beam for the verification of a treatment plan with a precision better than 1 mm. The maximum dose applied in the patient thereby is of the magnitude of 10 mGy.
Pawelke
J
J
Forschungszentrum Rossendorf, Institut für Kern- und Hadronenphysik, Dresden, Germany.
Byars
L
L
Enghardt
W
W
Fromm
W D
WD
Geissel
H
H
Hasch
B G
BG
Lauckner
K
K
Manfrass
P
P
Schardt
D
D
Sobiella
M
M
D001610:Beta Particles; D005462:Fluorine Radioisotopes; D006801:Humans; D009356:Neon; D010104:Oxygen Radioisotopes; D010781:Photography / Q000295:instrumentation; D011868:Radioisotopes; D011878:Radiotherapy; D012680:Sensitivity and Specificity; D014055:Tomography, Emission-Computed / Q000295:instrumentation* / Q000379:methods
D005462:Fluorine Radioisotopes; D010104:Oxygen Radioisotopes; D011868:Radioisotopes; D009356:Neon