title: Phenytoin-induced toxic epidermal necrolysis: a case report.
abstract: We present a case of phenytoin-induced toxic epidermal necrolysis resulting in 60-70% skin involvement. Systemic corticosteroids and prophylactic antibiotics used initially were discontinued, and subsequent management concentrated on intensive supportive treatment. The patient survived, but is left with disabling ocular complications.
authors: St. John's Dermatology Centre, London, UK.
authors: J D
authors: JD
authors: Creamer
authors: S J
authors: SJ
authors: Whittaker
authors: M
authors: M
authors: Kerr-Muir
authors: N P
authors: NP
authors: Smith
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D005128:Eye Diseases / Q000139:chemically induced / Q000628:therapy; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000473:pathology / Q000628:therapy
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin