title: Breast cancer risk and residence near industry or traffic in Nassau and Suffolk Counties, Long Island, New York.
abstract: A case-control interview study was used to evaluate the relationship between breast cancer risk and residential proximity to industrial facilities and traffic for pre- and postmenopausal women in Nassau and Suffolk Counties on Long Island, New York. A geographic information system was used to assign industry and traffic counts to 1-km2 grid cells (5-kM2 grid cells for traffic) and to assign potential exposure values to study subjects, based on 20-y residential histories. A significantly elevated risk of breast cancer was observed among postmenopausal subjects who were ever potentially exposed to chemical facilities (Nassau County adjusted odds ratio [OR] = 1.61, 95% confidence interval [95% CI] = 1.06-2.43; Suffolk County adjusted OR = 1.58, 95% CI = 0.71-3.51. This elevated risk, however, was not observed among premenopausal subjects. Risk increased for post-menopausal subjects as number of chemical facilities increased from one (adjusted OR = 1.45, 95% CI = 0.93-2.25) to two or more (adjusted OR = 3.47, 95% CI = 1.06-11.38). Crude and adjusted ORs for high traffic density were elevated among Nassau--but not Suffolk--county subjects and were not significant statistically.
authors: Division of Occupational Health and Environmental Epidemiology, New York State Department of Health, Albany 12203, USA.
authors: E L
authors: EL
authors: Lewis-Michl
authors: J M
authors: JM
authors: Melius
authors: L R
authors: LR
authors: Kallenbach
authors: C L
authors: CL
authors: Ju
authors: T O
authors: TO
authors: Talbot
authors: M F
authors: MF
authors: Orr
authors: P E
authors: PE
authors: Lauridsen
mesh_terms: D000328:Adult; D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000209:etiology; D016022:Case-Control Studies; D004781:Environmental Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D015994:Incidence; D007220:Industrial Waste / Q000009:adverse effects* / Q000706:statistics & numerical data; D008593:Menopause; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D012111:Residence Characteristics / Q000706:statistics & numerical data; D012307:Risk Factors; D001335:Vehicle Emissions / Q000009:adverse effects*
chemical_list: D000393:Air Pollutants; D007220:Industrial Waste; D001335:Vehicle Emissions